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Sample records for activation monitor cream

  1. OCT monitoring of cosmetic creams in human skin in vivo

    NASA Astrophysics Data System (ADS)

    Han, Seung Hee; Yoon, Chang Han; Conroy, Leigh; Vitkin, I. Alex

    2012-02-01

    Optical coherence tomography (OCT) is a tool currently used for noninvasive diagnosis of human disease as well as for monitoring treatment during or after therapy. In this study, OCT was used to examine penetration and accumulation of cosmetic creams on human hand skin. The samples varied in collagen content with one formulation containing soluble collagen as its primary active ingredient. Collagen is a major connective tissue protein that is essential in maintaining health vitality and strength of many organs. The penetration and localization of collagen in cosmetic creams is thought to be the main determinant of the efficacy of new collagen synthesis. Detection and quantification of collagen in cosmetic creams applied to skin may thus help predict the eventual efficacy of the product in skin collagen regeneration. We hypothesize that the topically applied collagen may be detectable by OCT through its modulation of skin scattering properties. To test this hypothesis, we used a FDML swept-source optical coherence tomography (SS-OCT) system. A particular location on the skin of two male adult volunteers was used to investigate 4 different cosmetic creams. The duration of OCT monitoring of cosmetic penetration into skin ranged from 5 minutes to 2 hours following topical application. The results showed that OCT can discriminate between a cream with collagen and other collagen-free formulations. Thus it seems feasible that OCT intensity can monitor the in vivo effects of topical application of collagen contained in cosmetic formulations.

  2. Cytotoxic and antibacterial activity of the mixture of olive oil and lime cream in vitro conditions.

    PubMed

    Sumer, Zeynep; Yildirim, Gulay; Sumer, Haldun; Yildirim, Sahin

    2013-01-01

    The mixture of olive oil and lime cream has been traditionally used to treat external burns in the region of Hatay/Antakya and middle Anatolia. Olive oil and lime cream have been employed by many physicians to treat many ailments in the past. A limited number of studies have shown the antibacterial effect of olive oil and that it does not have any toxic effect on the skin. But we did not find any reported studies on the mixture of olive oil and lime cream. The aim of this paper is to investigate the cytotoxic and antibacterial activity of olive oil and lime cream individually or/and in combination in vitro conditions, by using disk-diffusion method and in cell culture. The main purpose in using this mixture is usually to clear burns without a trace. Agar overlay, MTT (Cytotoxicity assay) and antibacterial susceptibility tests were used to investigate the cytotoxic and antibacterial activity of olive oil and lime cream. We found that lime cream has an antibacterial activity but also cytotoxic on the fibroblasts. On the other hand olive oil has limited or no antibacterial effect and it has little or no cytotoxic on the fibroblasts. When we combined lime cream and olive oil, olive oil reduced its cytotoxic impact. These results suggest that mixture of olive oil and lime cream is not cytotoxic and has antimicrobial activity.

  3. Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera

    PubMed Central

    Marslin, Gregory; Selvakesavan, Rajendran K; Franklin, Gregory; Sarmento, Bruno; Dias, Alberto CP

    2015-01-01

    We report on the antimicrobial activity of a cream formulation of silver nanoparticles (AgNPs), biosynthesized using Withania somnifera extract. Aqueous extracts of leaves promoted efficient green synthesis of AgNPs compared to fruits and root extracts of W. somnifera. Biosynthesized AgNPs were characterized for their size and shape by physical-chemical techniques such as UV-visible spectroscopy, laser Doppler anemometry, transmission electron microscopy, scanning electron microscopy, atomic force microscopy, X-ray diffraction, and X-ray energy dispersive spectroscopy. After confirming the antimicrobial potential of AgNPs, they were incorporated into a cream. Cream formulations of AgNPs and AgNO3 were prepared and compared for their antimicrobial activity against human pathogens (Staphylococcus aureus, Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli, and Candida albicans) and a plant pathogen (Agrobacterium tumefaciens). Our results show that AgNP creams possess significantly higher antimicrobial activity against the tested organisms. PMID:26445537

  4. Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera.

    PubMed

    Marslin, Gregory; Selvakesavan, Rajendran K; Franklin, Gregory; Sarmento, Bruno; Dias, Alberto C P

    2015-01-01

    We report on the antimicrobial activity of a cream formulation of silver nanoparticles (AgNPs), biosynthesized using Withania somnifera extract. Aqueous extracts of leaves promoted efficient green synthesis of AgNPs compared to fruits and root extracts of W. somnifera. Biosynthesized AgNPs were characterized for their size and shape by physical-chemical techniques such as UV-visible spectroscopy, laser Doppler anemometry, transmission electron microscopy, scanning electron microscopy, atomic force microscopy, X-ray diffraction, and X-ray energy dispersive spectroscopy. After confirming the antimicrobial potential of AgNPs, they were incorporated into a cream. Cream formulations of AgNPs and AgNO3 were prepared and compared for their antimicrobial activity against human pathogens (Staphylococcus aureus, Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli, and Candida albicans) and a plant pathogen (Agrobacterium tumefaciens). Our results show that AgNP creams possess significantly higher antimicrobial activity against the tested organisms.

  5. Investigation of cream and ointment on antimicrobial activity of Mangifera indica extract.

    PubMed

    Awad El-Gied, Amgad A; Abdelkareem, Abdelkareem M; Hamedelniel, Elnazeer I

    2015-01-01

    Medicinal plants have curative properties due to the presence of various complex chemical substance of different composition, which are found as secondary plant metabolites in one or more parts of these plants. Mangifera indica Linn (MI L.) is a species of mango in the Anacardiaceae family. Phytoconstituents in the seed extracts may be responsible for the antimicrobial activity of the plant. The purpose of the study was to formulate and evaluate the antimicrobial herbal ointment and cream from extracts of the seeds of mango (MI L.) The formulated ointments containing oleaginous-based showed the best formulation compared to the emulsion water in oil type, the ointment and cream bases in different concentration 1%, 5% and 10%. The formulated ointment and cream of MI L. were subjected to evaluation of Uniformity of Weight, measurement of pH, viscosity, Spreadability, Acute skin irritation study, stability study and antimicrobial activity. Our study shows that MI has high potential as an antimicrobial agent when formulated as ointment and creams for topical use. Thus, the present study concludes that the formulated formulations of the MI are safe and efficient carriers, with potent antimicrobial activity.

  6. Investigation of cream and ointment on antimicrobial activity of Mangifera indica extract

    PubMed Central

    Awad El-Gied, Amgad A.; Abdelkareem, Abdelkareem M.; Hamedelniel, Elnazeer I.

    2015-01-01

    Medicinal plants have curative properties due to the presence of various complex chemical substance of different composition, which are found as secondary plant metabolites in one or more parts of these plants. Mangifera indica Linn (MI L.) is a species of mango in the Anacardiaceae family. Phytoconstituents in the seed extracts may be responsible for the antimicrobial activity of the plant. The purpose of the study was to formulate and evaluate the antimicrobial herbal ointment and cream from extracts of the seeds of mango (MI L.) The formulated ointments containing oleaginous-based showed the best formulation compared to the emulsion water in oil type, the ointment and cream bases in different concentration 1%, 5% and 10%. The formulated ointment and cream of MI L. were subjected to evaluation of Uniformity of Weight, measurement of pH, viscosity, Spreadability, Acute skin irritation study, stability study and antimicrobial activity. Our study shows that MI has high potential as an antimicrobial agent when formulated as ointment and creams for topical use. Thus, the present study concludes that the formulated formulations of the MI are safe and efficient carriers, with potent antimicrobial activity. PMID:25878974

  7. Promotion and computation of inhibitory effect on tyrosinase activity of herbal cream by incorporating indigenous medicinal plants.

    PubMed

    Sahu, Ram Kumar; Roy, Amit; Dwivedi, Jaya; Jha, Arvind Kumar

    2014-01-01

    Herbal cream imparts a chief role in regulating melanin production of skin. The phytoconstituents present in herbal cream impact biological functions of skin and contribute nutrients required for the healthy skin. In the present study, it was envisaged to prepare three batches of herbal cream (HC1, HC2 and HC3) containing ethanol extracts of Emblica officinalis (fruits), Daucus carota (root), Mangifera indica (leaves), Mentha arvensis (leaves), Terminalia arjuna (bark) and Cucumis sativus (fruits) and investigated the prepared cream for inhibitory effect on tyrosinase activity. The herbal cream was formulated by incorporating different ratio of extracts, by using cream base. Each formulation HC1, HC2 and HC3 were segregated into three different formulations (HC1.1, HC1.2, HC1.3, HC2.1, HC2.2, HC2.3, HC3.1, HC3.2 and HC3.3) by incorporating increasing ratio of extract in formulation. The HC3.2 cream produces highest tyrosinase inhibitory effect 65.23 +/- 0.07%, while the HC2.1 exhibited minimum tyrosinase inhibitory effect 26.19 +/- 0.08% compared to other prepared cream. Comparison of the inhibitory activity of the formulations demonstrated that the rank order was HC3.2 > HC3.3 > HC1.2 > HC1.3 > HC3.1 > HC1.1 > HC2.3 > HC2.2 > HC2.1. It has been observed from the result that the formulations of antityrosinase activity were not concentrate dependent. This finding suggests that decrease in antityrosinase activity of HC1 and HC3 might be considering that the incompatibility of the higher extract content with the base of cream. The HC3 produce the maximum inhibitory effects on tyrosinase activity might be due to higher level of polyphenol and flavonoids present in extracts.

  8. Development and evaluation of sunscreen creams containing morin-encapsulated nanoparticles for enhanced UV radiation protection and antioxidant activity.

    PubMed

    Shetty, Pallavi Krishna; Venuvanka, Venkatesh; Jagani, Hitesh Vitthal; Chethan, Gejjalagere Honnappa; Ligade, Virendra S; Musmade, Prashant B; Nayak, Usha Y; Reddy, Meka Sreenivasa; Kalthur, Guruprasad; Udupa, Nayanabhirama; Rao, Chamallamudi Mallikarjuna; Mutalik, Srinivas

    2015-01-01

    The objective of present work was to develop novel sunscreen creams containing polymeric nanoparticles (NPs) of morin. Polymeric NPs containing morin were prepared and optimized. The creams containing morin NPs were also prepared and evaluated. Optimized NPs exhibited particle size of 90.6 nm and zeta potential of -31 mV. The entrapment efficiency of morin, within the polymeric NPs, was found to be low (12.27%). Fourier transformed infrared spectroscopy and differential scanning calorimetry studies revealed no interaction between morin and excipients. Transmission electron microscopy and atomic force microscopy revealed that the NPs were spherical in shape with approximately 100 nm diameter. Optimized NPs showed excellent in vitro free radical scavenging activity. Skin permeation and deposition of morin from its NPs was higher than its plain form. Different sunscreen creams (SC1-SC8) were formulated by incorporating morin NPs along with nano zinc oxide and nano titanium dioxide. SC5 and SC8 creams showed excellent sun protection factor values (≈40). In vitro and in vivo skin permeation studies of sunscreen creams containing morin NPs indicated excellent deposition of morin within the skin. Morin NPs and optimized cream formulations (SC5 and SC8) did not exhibit cytotoxicity in Vero and HaCaT cells. Optimized sunscreen creams showed excellent dermal safety. SC5 and SC8 creams demonstrated exceptional in vivo antioxidant effect (estimation of catalase, superoxide dismutase, and glutathione) in UV radiation-exposed rats. The optimized sunscreen creams confirmed outstanding UV radiation protection as well as antioxidant properties.

  9. Development and evaluation of sunscreen creams containing morin-encapsulated nanoparticles for enhanced UV radiation protection and antioxidant activity

    PubMed Central

    Shetty, Pallavi Krishna; Venuvanka, Venkatesh; Jagani, Hitesh Vitthal; Chethan, Gejjalagere Honnappa; Ligade, Virendra S; Musmade, Prashant B; Nayak, Usha Y; Reddy, Meka Sreenivasa; Kalthur, Guruprasad; Udupa, Nayanabhirama; Rao, Chamallamudi Mallikarjuna; Mutalik, Srinivas

    2015-01-01

    The objective of present work was to develop novel sunscreen creams containing polymeric nanoparticles (NPs) of morin. Polymeric NPs containing morin were prepared and optimized. The creams containing morin NPs were also prepared and evaluated. Optimized NPs exhibited particle size of 90.6 nm and zeta potential of −31 mV. The entrapment efficiency of morin, within the polymeric NPs, was found to be low (12.27%). Fourier transformed infrared spectroscopy and differential scanning calorimetry studies revealed no interaction between morin and excipients. Transmission electron microscopy and atomic force microscopy revealed that the NPs were spherical in shape with approximately 100 nm diameter. Optimized NPs showed excellent in vitro free radical scavenging activity. Skin permeation and deposition of morin from its NPs was higher than its plain form. Different sunscreen creams (SC1–SC8) were formulated by incorporating morin NPs along with nano zinc oxide and nano titanium dioxide. SC5 and SC8 creams showed excellent sun protection factor values (≈40). In vitro and in vivo skin permeation studies of sunscreen creams containing morin NPs indicated excellent deposition of morin within the skin. Morin NPs and optimized cream formulations (SC5 and SC8) did not exhibit cytotoxicity in Vero and HaCaT cells. Optimized sunscreen creams showed excellent dermal safety. SC5 and SC8 creams demonstrated exceptional in vivo antioxidant effect (estimation of catalase, superoxide dismutase, and glutathione) in UV radiation-exposed rats. The optimized sunscreen creams confirmed outstanding UV radiation protection as well as antioxidant properties. PMID:26508854

  10. Penciclovir Cream

    MedlinePlus

    Penciclovir comes as a cream. It is usually used externally every 2 hours while you are awake for 4 days. Follow the directions on your ... Clean and dry the area before applying the cream to avoid spreading the infection. Rub the cream ...

  11. Aldehyde dehydrogenase activity in Lactococcus chungangensis: Application in cream cheese to reduce aldehyde in alcohol metabolism.

    PubMed

    Konkit, Maytiya; Choi, Woo Jin; Kim, Wonyong

    2016-03-01

    Previous studies have shown that the metabolic capability of colonic microflora may be at least as high as that of the liver or higher than that of the whole human body. Aldehyde dehydrogenase (ALDH) is an enzyme produced by these bacteria that can metabolize acetaldehyde, produce from ethanol to acetate. Lactococcus species, which is commonly used as a starter in dairy products, was recently found to possess the ALDH gene, and the activity of this enzyme was determined. In this study, the ALDH activity of Lactococcus chungangensis CAU 28(T) and 11 other type strains in the genus Lactococcus was studied. Only 5 species, 3 of dairy origin (Lactococcus lactis ssp. lactis KCTC 3769(T), Lactococcus lactis ssp. cremoris KCCM 40699(T), and Lactococcus raffinolactis DSM 20443(T)) and 2 of nondairy origin (Lactococcus fujiensis NJ317(T) and L. chungangensis CAU 28(T)), showed ALDH activity and possessed a gene encoding ALDH. All of these strains were capable of making cream cheese. Among the strains, L. chungangensis produced cream cheese that contained the highest level of ALDH and was found to reduce the level of acetaldehyde in the serum of mice. These results predict a promising role for L. chungangensis CAU28(T) to be used in cheese that can be developed as functional food.

  12. Alcohol dehydrogenase activity in Lactococcus chungangensis: application in cream cheese to moderate alcohol uptake.

    PubMed

    Konkit, Maytiya; Choi, Woo Jin; Kim, Wonyong

    2015-09-01

    Many human gastrointestinal facultative anaerobic and aerobic bacteria possess alcohol dehydrogenase (ADH) activity and are therefore capable of oxidizing ethanol to acetaldehyde. However, the ADH activity of Lactococcus spp., except Lactococcus lactis ssp. lactis, has not been widely determined, though they play an important role as the starter for most cheesemaking technologies. Cheese is a functional food recognized as an aid to digestion. In the current study, the ADH activity of Lactococcus chungangensis CAU 28(T) and 11 reference strains from the genus Lactococcus was determined. Only 5 strains, 3 of dairy origin, L. lactis ssp. lactis KCTC 3769(T), L. lactis ssp. cremoris KCCM 40699(T), and Lactococcus raffinolactis DSM 20443(T), and 2 of nondairy origin, Lactococcus fujiensis NJ317(T) and Lactococcus chungangensis CAU 28(T) KCTC 13185(T), showed ADH activity and possessed the ADH gene. All these strains were capable of making cheese, but the highest level of ADH activity was found in L. chungangensis, with 45.9nmol/min per gram in tryptic soy broth and 65.8nmol/min per gram in cream cheese. The extent that consumption of cheese, following imbibing alcohol, reduced alcohol uptake was observed by following the level of alcohol in the serum of mice. The results show a potential novel benefit of cheese as a dairy functional food.

  13. Sports cream overdose

    MedlinePlus

    Sports creams are creams or ointments used to treat aches and pains. Sports cream overdose can occur if someone uses this ... Two ingredients in sports creams that can be poisonous are: Menthol Methyl salicylate

  14. MCO Monitoring activity description

    SciTech Connect

    SEXTON, R.A.

    1998-11-09

    Spent Nuclear Fuel remaining from Hanford's N-Reactor operations in the 1970s has been stored under water in the K-Reactor Basins. This fuel will be repackaged, dried and stored in a new facility in the 200E Area. The safety basis for this process of retrieval, drying, and interim storage of the spent fuel has been established. The monitoring of MCOS in dry storage is a currently identified issue in the SNF Project. This plan outlines the key elements of the proposed monitoring activity. Other fuel stored in the K-Reactor Basins, including SPR fuel, will have other monitoring considerations and is not addressed by this activity description.

  15. We Scream for Nano Ice Cream

    ERIC Educational Resources Information Center

    Jones, M. Gail; Krebs, Denise L.; Banks, Alton J.

    2011-01-01

    There is a wide range of new products emerging from nanotechnology, and "nano ice cream" is an easy one that you can use to teach topics from surface area to volume applications. In this activity, students learn how ice cream can be made smoother and creamier tasting through nanoscience. By using liquid nitrogen to cool the cream mixture, students…

  16. Nutritional value, chemical composition, antioxidant activity and enrichment of cream cheese with chestnut mushroom Agrocybe aegerita (Brig.) Sing.

    PubMed

    Petrović, Jovana; Glamočlija, Jasmina; Stojković, Dejan; Ćirić, Ana; Barros, Lillian; Ferreira, Isabel C F R; Soković, Marina

    2015-10-01

    A very well-known and appreciated mushroom, Agrocybe aegerita (Brig.) Sing, was the subject of chemical profiling, antioxidant assays and sensory evaluation test in cream cheese. Methanolic extract obtained from a wild sample of A. aegerita fruiting body was fully chemically identified. Sample was found to be rich in carbohydrates (84.51 g/100 g dw), ash and proteins (6.69 g/100 g dw and 6.68 g/100 g dw, respectively). Trehalose was the main free sugar while malic acid was the most abundant organic acid. Four isoforms of tocopherols were identified; γ- tocopherol was the dominant isoform with 86.08 μg/100 g dw, followed by β- tocopherol, δ-tocopherol and α-tocopherol (8.80 μg/100 g dw, 3.40 μg/100 g dw and 2.10 μg/100 g dw, respectively). Polyunsaturated fatty acids were predominant, with linoleic acid as the most prominent one (78.40 %). Methanolic extract of chestnut mushroom exhibited high antioxidant activity. Sensory evaluation test included grading by panelists and comparing the overall acceptability of cream cheese alone and enriched cream cheese with dry powder of A. aegerita. General conclusion of the participants was that the newly developed product was more likeable in comparison to cream cheese alone. Due to the health-beneficial effects of antioxidants and wealth of chemically identified nutrients, A. aegerita is a promising starting material for incorporation on larger scale products.

  17. Let's Make Metric Ice Cream

    ERIC Educational Resources Information Center

    Zimmerman, Marianna

    1975-01-01

    Describes a classroom activity which involved sixth grade students in a learning situation including making ice cream, safety procedures in a science laboratory, calibrating a thermometer, using metric units of volume and mass. (EB)

  18. Small Active Radiation Monitor

    NASA Technical Reports Server (NTRS)

    Badhwar, Gautam D.

    2004-01-01

    A device, named small active radiation monitor, allows on-orbit evaluations during periods of increased radiation, after extravehicular activities, or at predesignated times for crews on such long-duration space missions as on the International Space Station. It also permits direct evaluation of biological doses, a task now performed using a combination of measurements and potentially inaccurate simulations. Indeed the new monitor can measure a full array of radiation levels, from soft x-rays to hard galactic cosmic-ray particles. With refinement, it will benefit commercial (nuclear power-plant workers, airline pilots, medical technicians, physicians/dentists, and others) and military personnel as well as the astronauts for whom thermoluminescent dosimeters are inadequate. Civilian and military personnel have long since graduated from film badges to thermoluminescent dosimeters. Once used, most dosimeters must be returned to a central facility for processing, a step that can take days or even weeks. While this suffices for radiation workers for whom exposure levels are typically very low and of brief duration, it does not work for astronauts. Even in emergencies and using express mail, the results can often be delayed by as much as 24 hours. Electronic dosimeters, which are the size of electronic oral thermometers, and tattlers, small electronic dosimeters that sound an alarm when the dose/dose rate exceeds preset values, are also used but suffer disadvantages similar to those of thermoluminescent dosimeters. None of these devices fully answers the need of rapid monitoring during the space missions. Instead, radiation is monitored by passive detectors, which are read out after the missions. Unfortunately, these detectors measure only the absorbed dose and not the biologically relevant dose equivalent. The new monitor provides a real-time readout, a time history of radiation exposures (both absorbed dose and biologically relevant dose equivalent), and a count of the

  19. The stability and blanching efficiency of some Betnelan-V cream dilutions.

    PubMed

    Boonsaner, P; Remon, J P; De Rudder, D

    1986-04-01

    In this study Betnelan-V cream was diluted with Beeler's basis and Cold cream. Cold Cream reduced the skin-blanching activity of the original cream more than Beeler's base. The stability of betamethasone-17-valerate was better in a Beeler's basis dilution than in a Cold cream dilution.

  20. Monitoring international nuclear activity

    SciTech Connect

    Firestone, R.B.

    2006-05-19

    The LBNL Table of Isotopes website provides primary nuclearinformation to>150,000 different users annually. We have developedthe covert technology to identify users by IP address and country todetermine the kinds of nuclear information they are retrieving. Wepropose to develop pattern recognition software to provide an earlywarning system to identify Unusual nuclear activity by country or regionSpecific nuclear/radioactive material interests We have monitored nuclearinformation for over two years and provide this information to the FBIand LLNL. Intelligence is gleaned from the website log files. Thisproposal would expand our reporting capabilities.

  1. Ice Cream Headaches

    MedlinePlus

    Diseases and Conditions Ice cream headaches By Mayo Clinic Staff Ice cream headaches are brief, stabbing headaches that can happen when you eat, drink or inhale something cold. Digging into an ice cream cone is a common trigger, but eating or ...

  2. Enhancement of skin radical scavenging activity and stratum corneum lipids after the application of a hyperforin-rich cream.

    PubMed

    Haag, S F; Tscherch, K; Arndt, S; Kleemann, A; Gersonde, I; Lademann, J; Rohn, S; Meinke, M C

    2014-02-01

    Hyperforin is well-known for its anti-inflammatory, anti-tumor, anti-bacterial, and antioxidant properties. The application of a hyperforin-rich verum cream could strengthen the skin barrier function by reducing radical formation and stabilizing stratum corneum lipids. Here, it was investigated whether topical treatment with a hyperforin-rich cream increases the radical protection of the skin during VIS/NIR irradiation. Skin lipid profile was investigated applying HPTLC on skin lipid extracts. Furthermore, the absorption- and scattering coefficients, which influence radical formation, were determined. 11 volunteers were included in this study. After a single cream application, VIS/NIR-induced radical formation could be completely inhibited by both verum and placebo showing an immediate protection. After an application period of 4weeks, radical formation could be significantly reduced by 45% following placebo application and 78% after verum application showing a long-term protection. Furthermore, the skin lipids in both verum and placebo groups increased directly after a single cream application but only significantly for ceramide [AP], [NP1], and squalene. After long-term cream application, concentration of cholesterol and the ceramides increased, but no significance was observed. These results indicate that regular application of the hyperforin-rich cream can reduce radical formation and can stabilize skin lipids, which are responsible for the barrier function.

  3. Monitoring active volcanoes

    USGS Publications Warehouse

    Tilling, Robert I.

    1987-01-01

    One of the most spectacular, awesomely beautiful, and at times destructive displays of natural energy is an erupting volcano, belching fume and ash thousands of meters into the atmosphere and pouring out red-hot molten lava in fountains and streams. Countless eruptions in the geologic past have produced volcanic rocks that form much of the Earth's present surface. The gradual disintegration and weathering of these rocks have yielded some of the richest farmlands in the world, and these fertile soils play a significant role in sustaining our large and growing population. Were it not for volcanic activity, the Hawaiian Islands with their sugar cane and pineapple fields and magnificent landscapes and seascapes would not exist to support their residents and to charm their visitors. Yet, the actual eruptive processes are catastrophic and can claim life and property.

  4. Processing effects on physicochemical properties of creams formulated with modified milk fat.

    PubMed

    Bolling, J C; Duncan, S E; Eigel, W N; Waterman, K M

    2005-04-01

    Type of thermal process [high temperature, short time pasteurization (HTST) or ultra-high temperature pasteurization (UHT)] and homogenization sequence (before or after pasteurization) were examined for influence on the physicochemical properties of natural cream (20% milk fat) and creams formulated with 20% low-melt, fractionated butteroil emulsified with skim milk, or buttermilk and butter-derived aqueous phase. Homogenization sequence influenced physicochemical makeup of the creams. Creams homogenized before pasteurization contained more milk fat surface material, higher phospholipid levels, and less protein at the milk fat interface than creams homogenized after pasteurization. Phosphodiesterase I activity was higher (relative to protein on lipid globule surface) when cream was homogenized before pasteurization. Creams formulated with skim milk and modified milk fat had relatively more phospholipid adsorbed at the milk fat interface. Ultra-high-temperature-pasteurized natural and reformulated creams were higher in viscosity at all shear rates investigated compared with HTST-pasteurized creams. High-temperature, short time-pasteurized natural cream was more viscous than HTST-pasteurized reformulated creams at most shear rates investigated. High-temperature, short time-pasteurized creams had better emulsion stability than UHT-pasteurized creams. Cream formulated with buttermilk had creaming stability most comparable to natural cream, and cream formulated with skim milk and modified butteroil was least stable to creaming. Most creams feathered in a pH range of 5.00 to 5.20, indicating that they were moderately stable to slightly unstable emulsions. All processing sequences yielded creams within sensory specifications with the exception of treatments homogenized before UHT pasteurization and skim milk formulations homogenized after UHT pasteurization.

  5. Active Job Monitoring in Pilots

    NASA Astrophysics Data System (ADS)

    Kuehn, Eileen; Fischer, Max; Giffels, Manuel; Jung, Christopher; Petzold, Andreas

    2015-12-01

    Recent developments in high energy physics (HEP) including multi-core jobs and multi-core pilots require data centres to gain a deep understanding of the system to monitor, design, and upgrade computing clusters. Networking is a critical component. Especially the increased usage of data federations, for example in diskless computing centres or as a fallback solution, relies on WAN connectivity and availability. The specific demands of different experiments and communities, but also the need for identification of misbehaving batch jobs, requires an active monitoring. Existing monitoring tools are not capable of measuring fine-grained information at batch job level. This complicates network-aware scheduling and optimisations. In addition, pilots add another layer of abstraction. They behave like batch systems themselves by managing and executing payloads of jobs internally. The number of real jobs being executed is unknown, as the original batch system has no access to internal information about the scheduling process inside the pilots. Therefore, the comparability of jobs and pilots for predicting run-time behaviour or network performance cannot be ensured. Hence, identifying the actual payload is important. At the GridKa Tier 1 centre a specific tool is in use that allows the monitoring of network traffic information at batch job level. This contribution presents the current monitoring approach and discusses recent efforts and importance to identify pilots and their substructures inside the batch system. It will also show how to determine monitoring data of specific jobs from identified pilots. Finally, the approach is evaluated.

  6. Anti-Pruritic Efficacy of Itch Relief Lotion and Cream in Patients With Atopic History: Comparison With Hydrocortisone Cream.

    PubMed

    Zirwas, Matthew J; Barkovic, Sylvia

    2017-03-01

    Objective: To evaluate the speed of onset and duration of relief of two ceramide-containing formulations with 1% pramoxine hydroxide (CeraVe® Itch Relief Lotion and Cream,Valeant Pharmaceuticals North America LLC, Irvine, CA) in patients with atopic history, including those with active flare and the comparative efficacy of CeraVe Itch Relief Cream to hydrocortisone 1% cream and night-time itch relief with continued use.

  7. Ice Cream Stick Math.

    ERIC Educational Resources Information Center

    Paddock, Cynthia

    1992-01-01

    Described is a teaching technique which uses the collection of ice cream sticks as a means of increasing awareness of quantity in a self-contained elementary special class for students with learning disabilities and mild mental retardation. (DB)

  8. Ex vivo studies for the passive transdermal delivery of low-dose naltrexone from a cream; detection of naltrexone and its active metabolite, 6β-naltrexol, using a novel LC Q-ToF MS assay.

    PubMed

    Dodou, Kalliopi; Armstrong, Andrew; Kelly, Ivan; Wilkinson, Simon; Carr, Kevin; Shattock, Paul; Whiteley, Paul

    2015-01-01

    Naltrexone (NTX) is a long-acting opiate antagonist. Low-dose naltrexone (LDN) therapy has shown promising results in the treatment of several autoimmune disorders. Our aim was to formulate NTX into a cream for the delivery of LDN and develop an analytical technique for the quantification of NTX and its active metabolite 6-β-naltrexol (NTXol) during transdermal diffusion cell permeation studies. A 1% w/w NTX cream was formulated and drug permeation was examined over 24 h using static Franz diffusion cells mounted with pig skin. A Liquid Chromatography Quadrupole-Time of Flight Mass Spectrometry (LC-MS Q-ToF) method was developed for the detection of NTX and NTXol in the receptor solution, skin membrane and residual cream on the donor chamber after completion of the diffusion studies. The cream formulation exhibited steady state release of NTX over 24 h after an initial lag time of 2.74 h. The bioconversion of NTX to NTXol in the skin membrane was 1.1%. It was concluded that the cream may be an effective formulation for the sustained transdermal delivery of LDN. The novel LC Q-ToF MS method allowed the accurate measurement of NTX and NTXol levels across the diffusion cell assemblies and the quantification of NTX metabolism in the skin.

  9. Anatahan Activity and Monitoring, 2005

    NASA Astrophysics Data System (ADS)

    Lockhart, A.; White, R.; Koyanagi, S.; Trusdell, F.; Kauahikaua, J.; Marso, J.; Ewert, J.

    2005-12-01

    Anatahan volcano began erupting in 2003 and continued with a second eruptive phase in 2004. In January 2005 the volcano began a sequence of eruptions and unrest that continues as of September 2005. The activity has been characterized by punctuated episodes of very steamy strombolian activity and vigorous ash emission. Some of the ash emissions have reached 50,000-foot elevations, with VOG and ash occasionally reaching the Philippines and southernmost Japan, over 1000 miles away. Vigorous ash emission has been almost continuous since June 2005. A M4.8 long-period earthquake (LP) occurred in mid-August, one of the largest LPs recorded on the planet in the last quarter-century. Real-time monitoring consisting of a few telemetered short-period seismometers and acoustic sensors has been severely hampered by ashfall on the small island. Monitoring efforts have been focused on the aircraft/ash hazard, with the goal of providing the FAA and airline industry with rapid notice of seismic signatures that may indicate ash columns rising to the altitude of airline traffic, or nominally above 20,000-30,000 ft.

  10. Retrospective Study on the Analgesic Activity of a Topical (TT-CTAC) Cream in Patients With Diabetic Neuropathy and Other Chronic Pain Conditions.

    PubMed

    Somberg, John C; Molnar, Janos

    2015-01-01

    Treatment of chronic pain in diabetic neuropathy or neuropathic pain of other origins is challenging. Compounded topical formulations have evolved as potential treatment options. The objective of this retrospective study was to evaluate the efficacy of a compounded topical cream (Transdermal Therapeutics). Two versions of TT-CTAC cream were evaluated: cream 6B and cream 7B. Both creams contain ketamine (10%), baclofen (2%), gabapentin (6%), amitriptyline (4%), bupivacaine (2%), and clonidine (0.2%). Additionally, one cream (7B) contains nifedipine (2%). The primary efficacy outcome was the change in numeric pain intensity score from pretreatment to posttreatment. Secondary outcomes were qualitative grading (excellent, good, poor, or no effect), reduction in oral medication, and avoiding referral to a pain specialist. Information on 283 patients was evaluated, 205 received the 7B and 78 received 6B creams. The pain score decreased by 2.4 ± 2.4 (35%) with the 6B cream (from 7.8 ± 1.6 to 5.4 ± 2.0, P < 0.001) and by 3.0 ± 2.4 (40%) with the 7B cream (from 7.5 ± 1.7 to 4.5 ± 2.2, P < 0.001). Excellent or good effects were reported in 82% of the patients in the 6B and in 70% in the 7B groups. Reduction in oral pain medication was seen in 35% of the patients in the 7B and in 20% in the 6B groups. In the opinion of the treating physicians, the cream therapy caused the avoidance of a pain specialist referral in 53% of the patients in the 6B and in 39% in the 7B groups. The creams were equally effective in diabetic neuropathy, neuropathic pain, or other chronic pain states. We conclude that both creams provided excellent pain relief in the majority of the patients studied and may be a useful modality for pain therapy.

  11. 21 CFR 131.155 - Light cream.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Light cream. 131.155 Section 131.155 Food and... CONSUMPTION MILK AND CREAM Requirements for Specific Standardized Milk and Cream § 131.155 Light cream. (a) Description. Light cream is cream which contains not less than 18 percent but less than 30 percent milkfat....

  12. 21 CFR 131.155 - Light cream.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Light cream. 131.155 Section 131.155 Food and... CONSUMPTION MILK AND CREAM Requirements for Specific Standardized Milk and Cream § 131.155 Light cream. (a) Description. Light cream is cream which contains not less than 18 percent but less than 30 percent milkfat....

  13. 21 CFR 131.155 - Light cream.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Light cream. 131.155 Section 131.155 Food and... CONSUMPTION MILK AND CREAM Requirements for Specific Standardized Milk and Cream § 131.155 Light cream. (a) Description. Light cream is cream which contains not less than 18 percent but less than 30 percent milkfat....

  14. 21 CFR 131.155 - Light cream.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Light cream. 131.155 Section 131.155 Food and... CONSUMPTION MILK AND CREAM Requirements for Specific Standardized Milk and Cream § 131.155 Light cream. (a) Description. Light cream is cream which contains not less than 18 percent but less than 30 percent milkfat....

  15. 21 CFR 131.149 - Dry cream.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Dry cream. 131.149 Section 131.149 Food and Drugs... CONSUMPTION MILK AND CREAM Requirements for Specific Standardized Milk and Cream § 131.149 Dry cream. (a) Description. Dry cream is the product obtained by removal of water only from pasteurized milk or cream or...

  16. 21 CFR 131.155 - Light cream.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Light cream. 131.155 Section 131.155 Food and... CONSUMPTION MILK AND CREAM Requirements for Specific Standardized Milk and Cream § 131.155 Light cream. (a) Description. Light cream is cream which contains not less than 18 percent but less than 30 percent milkfat....

  17. 21 CFR 131.150 - Heavy cream.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Heavy cream. 131.150 Section 131.150 Food and... CONSUMPTION MILK AND CREAM Requirements for Specific Standardized Milk and Cream § 131.150 Heavy cream. (a) Description. Heavy cream is cream which contains not less than 36 percent milkfat. It is pasteurized or...

  18. The Use of Noninvasive Optical Coherence Tomography to Monitor the Treatment Progress of Vismodegib and Imiquimod 5% Cream in a Transplant Patient with Advanced Basal Cell Carcinoma of the Nose

    PubMed Central

    Markowitz, Orit; Schwartz, Michelle

    2016-01-01

    Immunosuppressed transplant recipients have increased risk for the development of basal cell carcinoma skin cancers. While oral vismodegib therapy has been successful in treating locally advanced basal cell tumors, few studies document its use and efficacy in organ transplant patients. In this immunocompromised population, topical imiquimod 5% cream has been shown to be an effective and well-tolerated option for superficial and nodular basal cell carcinomas. To the authors’ knowledge, no data documents the use of optical coherence tomography, a noninvasive imaging technique, to monitor progress of such combined therapies on in vivo skin. The authors report the successful treatment of an extensive basal cell carcinoma on the nose of an immunosuppressed 54-year-old Caucasian man with a history of kidney and pancreas transplantations. By combining continuous noninvasive lesion monitoring with vismodegib 150mg/d therapy and adjuvant imiquimod 5% topical cream, the patient showed complete disease clearance on clinical, optical coherence tomography, and histological evaluation. This report supports the feasibility and efficacy of nonsurgical treatment of basal cell lesions in complicated transplant patients and the need for individualized treatment plans. A noninvasive follow-up tool, especially during nonsurgical therapy, is of critical value to ensure the best possible treatment outcome for the patient. PMID:27672417

  19. Antioxidant activities of tocopherols/tocotrienols and lipophilic antioxidant capacity of wheat, vegetable oils, milk and milk cream by using photochemiluminescence.

    PubMed

    Karmowski, Jasmin; Hintze, Victoria; Kschonsek, Josephine; Killenberg, Margrit; Böhm, Volker

    2015-05-15

    The purpose of this study was to measure the antioxidant activity (AOA) of tocopherols and tocotrienols by using photochemiluminescence (PCL). This method enables to detect total lipophilic antioxidants. The AOA of all vitamin E isomers depended on number and position of methyl groups in the chroman ring. Correlation between the AOA and the redox potential and the biological activity of the tocochromanols was observed. The second aim was to analyse different kinds of wheat, vegetable oils, milk and milk cream on their antioxidant capacity (AOC) by using PCL and α-TEAC. The contents of vitamin E and carotenoids were analysed by HPLC. Correlations between the sum of carotenoids and vitamin E and the AOC were detected. Based on high vitamin E contents, the oils had the highest and in contrast, the product macaroni showed the lowest AOC. A concentration-dependent effect was observed in both assays, PCL and α-TEAC.

  20. Herbal haemorrhoidal cream for haemorrhoids.

    PubMed

    Gurel, Ebru; Ustunova, Savas; Ergin, Bulent; Tan, Nur; Caner, Metin; Tortum, Osman; Demirci-Tansel, Cihan

    2013-10-31

    Although hemorrhoids are one of the most common diseases in the world, the exact etiology underlying the development of hemorrhoids is not clear. Many different ointments are currently used to treat hemorrhoids; however, there is little evidence of the efficacy of these treatments to support their use. The aim of this study was to compare different herbal creams used for the treatment of hemorrhoids. Twenty-eight male Wistar albino rats, 6-8 weeks old and weighing 160-180 g, were used in this study as 1-control, 2-croton oil, 3-croton oil+fig leaves+artichoke leaves+walnut husks and 4-croton oil+fig leaves+artichoke leaves+walnut husks+horse chestnut fruit. After 3 days of croton oil application, rats were treated with 0.1 ml of cream or saline twice a day for 15 days by syringe. Tissue and blood samples were collected for histological, immunohistochemical and biochemical studies. Statistical significance was determined using one-way ANOVA followed by Tukey's multiple comparison tests. Croton oil administration resulted in severe inflammation. The third group showed partial improvement in inflammation; however, the greatest degree of improvement was seen in the fourth group, and some recovered areas were observed. Myeloperoxidase immunoreactivity was found to be decreased in the third and fourth groups compared to the second group. Additionally, biochemical analyses (Myeloperoxidase, Malondyaldehyde, nitrate/nitrite and nitrotyrosine levels and Superoxide Dismutase activity) were in agreement with the histological and immunohistochemical results. In conclusion, croton oil causes inflammation in the anal area and results in hemorrhoids. Treatment with our herbal hemorrhoid creams demonstrated anti-inflammatory and anti-oxidant effects in this model.

  1. Treatment of scabies, permethrin 5% cream vs. crotamiton 10% cream.

    PubMed

    Pourhasan, Abolfazl; Goldust, Mohamad; Rezaee, Elham

    2013-01-01

    Scabies is one of the three most common skin disorders in children, along with tinea and pyoderma. The treatment of choice is still controversial. The aim of this study is to compare the efficacy of permethrin 5% cream vs. crotamiton 10% cream in the treatment of scabies. In total, 350 patients with scabies were enrolled, and randomized into two groups. The first group received permethrin 5% cream on two occasions with a one-week interval, while the second group received topical crotamiton 10% cream and were told to apply this twice daily for five consecutive days. The treatment was evaluated at intervals of 2 and 4 weeks, and the treatment was repeated if treatment failure was found at the 2-week follow-up. Two applications of permethrin 5 % cream provided a cure rate of 70% at the 2-week follow-up, which increased to 85% at the 4-week follow-up after repeating the treatment. Treatment with single applications of crotamiton 10% cream was effective in 45% of patients at the 2-week follow-up, which increased to 65% at the 4-week follow-up after this treatment was repeated. Two applications of permethrin 5% cream was as effective as single applications of crotamiton 10% cream at the 2-week follow-up. After repeating the treatment, permethrin 5 % cream was superior to crotamiton 10% cream at the 4-week follow up.

  2. Biofilm formation in an ice cream plant.

    PubMed

    Gunduz, Gulten Tiryaki; Tuncel, Gunnur

    2006-01-01

    The sites of biofilm formation in an ice cream plant were investigated by sampling both the production line and the environment. Experiments were carried out twice within a 20-day period. First, stainless steel coupons were fixed to surfaces adjacent to food contact surfaces, the floor drains and the doormat. They were taken for the analysis of biofilm at three different production stages. Then, biofilm forming bacteria were enumerated and also presence of Listeria monocytogenes was monitored. Biofilm forming isolates were selected on the basis of colony morphology and Gram's reaction; Gram negative cocci and rod, Gram positive cocci and spore forming isolates were identified. Most of the biofilm formations were seen on the conveyor belt of a packaging machine 8 h after the beginning of the production, 6.5 x 10(3) cfu cm(-2). Most of the Gram negative bacteria identified belong to Enterobacteriaceae family such as Proteus, Enterobacter, Citrobacter, Shigella, Escherichia, Edwardsiella. The other Gram negative microflora included Aeromonas, Plesiomonas, Moraxella, Pseudomonas or Alcaligenes spp. were also isolated. Gram positive microflora of the ice cream plant included Staphyloccus, Bacillus, Listeria and lactic acid bacteria such as Streptococcus, Leuconostoc or Pediococcus spp. The results from this study highlighted the problems of spread of pathogens like Listeria and Shigella and spoilage bacteria. In the development of cleaning and disinfection procedures in ice cream plants, an awareness of these biofilm-forming bacteria is essential for the ice cream plants.

  3. 7 CFR 58.326 - Plastic cream.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Plastic cream. 58.326 Section 58.326 Agriculture... Material § 58.326 Plastic cream. To produce plastic cream eligible for official certification, the quality of the cream used shall meet the requirements of cream acceptable for the manufacture of U.S....

  4. 7 CFR 58.327 - Frozen cream.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Frozen cream. 58.327 Section 58.327 Agriculture... Material § 58.327 Frozen cream. To produce frozen cream eligible for official certification, the quality of the cream used shall meet the requirements of cream acceptable for the manufacture of U.S. Grade AA...

  5. 21 CFR 131.160 - Sour cream.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Sour cream. 131.160 Section 131.160 Food and Drugs... CONSUMPTION MILK AND CREAM Requirements for Specific Standardized Milk and Cream § 131.160 Sour cream. (a) Description. Sour cream results from the souring, by lactic acid producing bacteria, of pasteurized...

  6. Ivermectin cream for rosacea.

    PubMed

    2015-11-01

    Rosacea is a chronic facial skin disease that mainly occurs in people aged over 30 years. It is common, with an estimated incidence of 1·7 per 1,000 person-years in general practice in the UK.(1,2) Rosacea can cause embarrassment, anxiety, low self-esteem and lack of confidence.(3) A new topical treatment has become available for the treatment of one of the clinical subtypes of rosacea. Ivermectin 10mg/g (1%) cream (Soolantra-Galderma) has received marketing authorisation for the treatment of inflammatory lesions of papulopustular rosacea in adults.(4) Here we review the safety and effectiveness of ivermectin cream in the treatment of rosacea and assess how it compares with standard therapies.

  7. 7 CFR 1000.16 - Fluid cream product.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Fluid cream product. 1000.16 Section 1000.16... Definitions § 1000.16 Fluid cream product. Fluid cream product means cream (other than plastic cream or frozen cream), including sterilized cream, or a mixture of cream and milk or skim milk containing 9 percent...

  8. Monitoring by Control Technique - Activated Carbon Adsorber

    EPA Pesticide Factsheets

    Stationary source emissions monitoring is required to demonstrate that a source is meeting the requirements in Federal or state rules. This page is about Activated Carbon Adsorber control techniques used to reduce pollutant emissions.

  9. Contact dermatitis to Hirudoid cream.

    PubMed

    Pecegueiro, M; Brandão, M; Pinto, J; Conçalo, S

    1987-11-01

    31 patients allergic to Hirudoid cream were patch tested with the ingredients. 29 were allergic to the cream base and 16 to one or more components. The most common allergens were myristyl alcohol, cetostearyl alcohol and parabens. 14 patients reacted only to the base. The results are discussed.

  10. The physics of ice cream

    NASA Astrophysics Data System (ADS)

    Clarke, Chris

    2003-05-01

    Almost everybody likes ice cream, so it can provide an excellent vehicle for discussing and demonstrating a variety of physical phenomena, such as Newton's law of cooling, Boyle's law and the relationship between microstructure and macroscopic properties (e.g. Young's modulus). Furthermore, a demonstration of freezing point depression can be used to make ice cream in the classroom!

  11. The Coffee and Cream Problem.

    ERIC Educational Resources Information Center

    Greenslade, Thomas B.

    1994-01-01

    Describes how Newton's Law of Cooling and the Method of Mixtures are used to solve the basic dilemma of whether to add the cool cream to the hot coffee or to let the black coffee cool down first and then add the cream. (ZWH)

  12. Terconazole Vaginal Cream, Vaginal Suppositories

    MedlinePlus

    Terconazole comes as a cream and suppository to insert into the vagina. It is usually used daily at bedtime for either 3 or 7 days. ... prescribed by your doctor.To use the vaginal cream or vaginal suppositories, read the instructions provided with ...

  13. From CREAM to ISS-CREAM: A Next Step in the Direct Measurement of Cosmic Rays

    NASA Astrophysics Data System (ADS)

    Angelaszek, David; Iss-Cream Collaboration

    2015-04-01

    The balloon-borne Cosmic Ray Energetics and Mass (CREAM) Experiment has carried out six successful ?ights around the continent of Antarctica for a total exposure of over 160 days. The CREAM Data Acquisition (CDAQ) software system, utilized on all six balloon missions, is a crucial component of the CREAM instrument that facilitates data-taking, monitoring, commanding and calibration of the entire apparatus. Currently, a CREAM payload is being developed for integration on the International Space Station (ISS) in the spring of 2015. The shift from a balloon-borne experiment to a space mission required numerous hardware modifications and introduces a new command and data handling environment. New operational considerations are also needed to accommodate a multi-year mission. These hardware, environmental and operational modifications must be accommodated in CDAQ. The nature of these modifications and how they are reflected in the CDAQ software are discussed here. This work was supported by NASA Headquarters under the NASA Earth and Space Science Fellowship Program-Grant NNX12AL57H, NASA Grant NNX11AC52G and their predecessors.

  14. 21 CFR 133.133 - Cream cheese.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Cream cheese. 133.133 Section 133.133 Food and... Products § 133.133 Cream cheese. (a) Description. (1) Cream cheese is the soft, uncured cheese prepared by..., nonfat milk, or cream, as defined in § 133.3, used alone or in combination. (2) Clotting enzymes....

  15. 21 CFR 524.450 - Clotrimazole cream.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Clotrimazole cream. 524.450 Section 524.450 Food... Clotrimazole cream. (a) Specifications. Each gram of cream contains 10 milligrams of clotrimazole. (b) Sponsor. See 000859 in § 510.600(c). (c) Conditions of use—(1) Amount. Apply 1/4-inch ribbon of cream...

  16. Monitoring Biological Activity at Geothermal Power Plants

    SciTech Connect

    Peter Pryfogle

    2005-09-01

    The economic impact of microbial growth in geothermal power plants has been estimated to be as high as $500,000 annually for a 100 MWe plant. Many methods are available to monitor biological activity at these facilities; however, very few plants have any on-line monitoring program in place. Metal coupon, selective culturing (MPN), total organic carbon (TOC), adenosine triphosphate (ATP), respirometry, phospholipid fatty acid (PLFA), and denaturing gradient gel electrophoresis (DGGE) characterizations have been conducted using water samples collected from geothermal plants located in California and Utah. In addition, the on-line performance of a commercial electrochemical monitor, the BIoGEORGE?, has been evaluated during extended deployments at geothermal facilities. This report provides a review of these techniques, presents data on their application from laboratory and field studies, and discusses their value in characterizing and monitoring biological activities at geothermal power plants.

  17. Inhibition of ice crystal growth in ice cream mix by gelatin hydrolysate.

    PubMed

    Damodaran, Srinivasan

    2007-12-26

    The inhibition of ice crystal growth in ice cream mix by gelatin hydrolysate produced by papain action was studied. The ice crystal growth was monitored by thermal cycling between -14 and -12 degrees C at a rate of one cycle per 3 min. It is shown that the hydrolysate fraction containing peptides in the molecular weight range of about 2000-5000 Da exhibited the highest inhibitory activity on ice crystal growth in ice cream mix, whereas fractions containing peptides greater than 7000 Da did not inhibit ice crystal growth. The size distribution of gelatin peptides formed in the hydrolysate was influenced by the pH of hydrolysis. The optimum hydrolysis conditions for producing peptides with maximum ice crystal growth inhibitory activity was pH 7 at 37 degrees C for 10 min at a papain to gelatin ratio of 1:100. However, this may depend on the type and source of gelatin. The possible mechanism of ice crystal growth inhibition by peptides from gelatin is discussed. Molecular modeling of model gelatin peptides revealed that they form an oxygen triad plane at the C-terminus with oxygen-oxygen distances similar to those found in ice nuclei. Binding of this oxygen triad plane to the prism face of ice nuclei via hydrogen bonding appears to be the mechanism by which gelatin hydrolysate might be inhibiting ice crystal growth in ice cream mix.

  18. Active personal radiation monitor for lunar EVA

    NASA Astrophysics Data System (ADS)

    Straume, Tore; Borak, Tom; Braby, L. A.; Lusby, Terry; Semones, Edward J.; Vazquez, Marcelo E.

    As astronauts return to the Moon-and this time, work for extended periods-there will be a critical need for crew personnel radiation monitoring as they operate lunar rovers or otherwise perform a myriad of extravehicular activities (EVAs). Our focus is on development of a small personal radiation monitor for lunar EVA that responds to the complex radiation quality and changing dose rates on the Moon. Of particular concern are active monitoring capabilities that provide both early warning and radiation dosimetry information during solar particle events (SPEs). To accomplish this, we are developing small detectors integrated with modern high speed, low power microelectronics to measure dose-rate and dose-mean lineal energy in real time. The monitor is designed to perform over the range of dose rates and LETs expected from both GCR and SPE radiations during lunar EVA missions. The monitor design provides simultaneous measurement of dose-equivalent rates at two tissue-equivalent depths simulating skin and marrow. The compact personal monitor is estimated to be the size of a cell phone and would fit on an EVA spacesuit (e.g., in backpack) or in a toolbox. The four-year development effort (which began December 2007) will result in a prototype radiation monitor field tested and characterized for the major radiations expected on the surface of the Moon. We acknowledge support from NSBRI through grants to NASA Ames Research Center (T. Straume, PI) and Colorado State University (T. Borak, PI).

  19. Proof of efficacy of Kamillosan(R) cream in atopic eczema.

    PubMed

    Patzelt-Wenczler, R; Ponce-Pöschl, E

    2000-04-19

    Kamillosan(R) cream contains chamomile extract as active principle manufactured from the chamomile sort Manzana which is rich in active principles and has been proved not to exhibit a chamomile-related allergen potential. For this reason Kamillosan(R) cream is suited for local therapy of atopic eczema. In a partially double-blind, randomized study carried out as a half-side comparison, Kamillosan(R) cream was tested vs. 0.5% hydrocortisone cream and the vehicle cream as placebo in patients suffering from medium-degree atopic eczema. After a 2-week treatment Kamillosan(R) cream showed a mild superiority towards 0.5% hydrocortisone and a marginal difference as compared to placebo.

  20. Job submission and management through web services: the experience with the CREAM service

    NASA Astrophysics Data System (ADS)

    Aiftimiei, C.; Andreetto, P.; Bertocco, S.; Fina, S. D.; Ronco, S. D.; Dorigo, A.; Gianelle, A.; Marzolla, M.; Mazzucato, M.; Sgaravatto, M.; Verlato, M.; Zangrando, L.; Corvo, M.; Miccio, V.; Sciaba, A.; Cesini, D.; Dongiovanni, D.; Grandi, C.

    2008-07-01

    Modern Grid middleware is built around components providing basic functionality, such as data storage, authentication, security, job management, resource monitoring and reservation. In this paper we describe the Computing Resource Execution and Management (CREAM) service. CREAM provides a Web service-based job execution and management capability for Grid systems; in particular, it is being used within the gLite middleware. CREAM exposes a Web service interface allowing conforming clients to submit and manage computational jobs to a Local Resource Management System. We developed a special component, called ICE (Interface to CREAM Environment) to integrate CREAM in gLite. ICE transfers job submissions and cancellations from the Workload Management System, allowing users to manage CREAM jobs from the gLite User Interface. This paper describes some recent studies aimed at assessing the performance and reliability of CREAM and ICE; those tests have been performed as part of the acceptance tests for integration of CREAM and ICE in gLite. We also discuss recent work towards enhancing CREAM with a BES and JSDL compliant interface.

  1. Chlorhexidine-calcium phosphate nanoparticles - Polymer mixer based wound healing cream and their applications.

    PubMed

    Viswanathan, Kaliyaperumal; Monisha, P; Srinivasan, M; Swathi, D; Raman, M; Dhinakar Raj, G

    2016-10-01

    In this work, we developed a wound healing cream composed of two different polymers, namely chitosan and gelatin with chlorhexidine along with calcium phosphate nanoparticles. The physicochemical properties of the prepared cream were investigated based on SEM, EDX, Raman, FTIR and the results indicated that the cream contained gelatin, chitosan, calcium phosphate nanoparticles and chlorhexidine. The maximum swelling ratio studies indicated that the ratio was around of 52±2.2 at pH7.4 and the value was increased in acidic and alkaline pH. The antimicrobial activity was tested against bacteria and the results indicated that, both chlorhexidine and the hybrid cream devoid of chlorhexidine exhibited antimicrobial activity but the chlorhexidine impregnated cream showed three fold higher antimicrobial activity than without chlorhexidine. In vivo wound healing promoting activities of hybrid cream containing 0.4mg/L chlorhexidine were evaluated on surgically induced dermal wounds in mice. The results indicated that the cream with incorporated chlorhexidine significantly enhanced healing compared with the control samples. For the field validations, the veterinary clinical animals were treated with the cream and showed enhanced healing capacity. In conclusion, a simple and efficient method for design of a novel wound healing cream has been developed for veterinary applications.

  2. Tactile perception of skin and skin cream by friction induced vibrations.

    PubMed

    Ding, Shuyang; Bhushan, Bharat

    2016-11-01

    Skin cream smooths, softens, and moistens skin by altering surface roughness and tribological properties of skin. Sliding generates vibrations that activate mechanoreceptors located in skin. The brain interprets tactile information to identify skin feel. Understanding the tactile sensing mechanisms of skin with and without cream treatment is important to numerous applications including cosmetics, textiles, and robotics sensors. In this study, frequency spectra of friction force and friction induced vibration signals were carried out to investigate tactile perception by an artificial finger sliding on skin. The influence of normal load, velocity, and cream treatment time were studied. Coherence between friction force and vibration signals were found. The amplitude of vibration decreased after cream treatment, leading to smoother perception. Increasing normal load or velocity between contacting surfaces generated a smoother perception with cream treatment, but rougher perception without treatment. As cream treatment time increases, skin becomes smoother. The related mechanisms are discussed.

  3. 34 CFR 300.120 - Monitoring activities.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false Monitoring activities. 300.120 Section 300.120 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE EDUCATION...

  4. 34 CFR 300.120 - Monitoring activities.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true Monitoring activities. 300.120 Section 300.120 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE EDUCATION OF CHILDREN...

  5. 34 CFR 300.120 - Monitoring activities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Monitoring activities. 300.120 Section 300.120 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE EDUCATION...

  6. 34 CFR 300.120 - Monitoring activities.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false Monitoring activities. 300.120 Section 300.120 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE EDUCATION...

  7. 34 CFR 300.120 - Monitoring activities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true Monitoring activities. 300.120 Section 300.120 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE EDUCATION OF CHILDREN...

  8. Reporters to monitor cellular MMP12 activity

    NASA Astrophysics Data System (ADS)

    Cobos-Correa, Amanda; Mall, Marcus A.; Schultz, Carsten

    2010-02-01

    Macrophage elastase, also called MMP12, belongs to a family of proteolytic enzymes whose best known physiological function is the remodeling of the extracellular matrix. Under certain pathological conditions, including inflammation, chronic overexpression of MMP12 has been observed and its elevated proteolytic activity has been suggested to be the cause of pulmonary emphysema. However, it was until recently impossible to monitor the activity of MMP12 under disease conditions, mainly due to a lack of detection methods. Recent development of new reporters for monitoring MMP12 activity in living cells, such as LaRee1, provided novel insights into the pathobiology of MMP12 in pulmonary inflammation.1 In the future, these reporters might contribute to improved diagnosis and in finding better treatments for chronic inflammatory lung diseases and emphysema. Our approach for visualizing MMP12 activity is based on peptidic, membrane-targeted FRET (Foerster Resonance Energy Transfer) reporters. Here we describe a set of new reporters containing different fluorophore pairs as well as modifications in the membrane-targeting lipid moiety. We studied the influence of these modifications on reporter performance and the reporter mobility on live cell membranes by FRAP (fluorescence recovery after photobleaching). Finally, we generated several new fluorescently labeled MMP inhibitors based on the peptidic reporter structures as prototypes for future tools to inhibit and monitor MMP activity at the same time.

  9. Using CREAM and CEMonitor for job submission and management in the gLite middleware

    NASA Astrophysics Data System (ADS)

    Aiftimiei, C.; Andreetto, P.; Bertocco, S.; Dalla Fina, S.; Dorigo, A.; Frizziero, E.; Gianelle, A.; Marzolla, M.; Mazzucato, M.; Mendez Lorenzo, P.; Miccio, V.; Sgaravatto, M.; Traldi, S.; Zangrando, L.

    2010-04-01

    In this paper we describe the use of CREAM and CEMonitor services for job submission and management within the gLite Grid middleware. Both CREAM and CEMonitor address one of the most fundamental operations of a Grid middleware, that is job submission and management. Specifically, CREAM is a job management service used for submitting, managing and monitoring computational jobs. CEMonitor is an event notification framework, which can be coupled with CREAM to provide the users with asynchronous job status change notifications. Both components have been integrated in the gLite Workload Management System by means of ICE (Interface to CREAM Environment). These software components have been released for production in the EGEE Grid infrastructure and, for what concerns the CEMonitor service, also in the OSG Grid. In this paper we report the current status of these services, the achieved results, and the issues that still have to be addressed.

  10. Anti-Leishmanial Activity (In Vitro and In Vivo) of Allicin and Allicin Cream Using Leishmania major (Sub-strain Zymowme LON4) and Balb/c Mice

    PubMed Central

    Metwally, Dina M.; Al-Olayan, Ebtesam M.; El-Khadragy, Manal F.; Alkathiri, Badriah

    2016-01-01

    Background Leishmania is a unicellular protozoan parasite that produces several human diseases, ranging from localized self-healing cutaneous lesions to deadly visceral infections. Objective The effect of allicin on the growth of Leishmania major (L. major) promastigotes was evaluated under in vitro conditions. Moreover, the efficacy of a topical allicin cream was examined in BALB/c (Bagg albino, laboratory-bred strain of the House Mouse) mice with cutaneous leishmanial lesions compared to the currently used drug, sodiumstibogluconate (pentostam). Methods Cytotoxiciy and promastigote proliferation were measured. Different concentrations (50, 100, 150, and 200 μM) of liquid allicin were tested on L. major promastigotes twice: after 24 and 48 hours using an MTT colorimetric assay. In the in vivo condition, the efficacies of allicin cream and liquid allicin at two concentrations (0.15 μM/mouse and 0.30 μM/mouse) were evaluated. Serum factors of the control and treated groups were tested to evaluate the toxic effects of allicin on the liver and kidney. Results Allicin at a concentration of 50 μM inhibited the growth of Leishmania promastigotes. Topical application of allicin cream reduced lesion sizes in mice. No significant differences in biochemical analysis were observed between the control and treated groups. Conclusions Allicin has antileishmanial effects under in vitro and in vivo conditions and may be used in clinical applications. PMID:27537199

  11. Active Sites Environmental Monitoring Program: Program plan

    SciTech Connect

    Ashwood, T.L.; Wickliff, D.S.; Morrissey, C.M.

    1992-02-01

    The Active Sites Environmental Monitoring Program (ASEMP), initiated in 1989, provides early detection and performance monitoring of transuranic (TRU) waste and active low-level waste (LLW) facilities at Oak Ridge National Laboratory (ORNL) in accordance with US Department of Energy (DOE) Order 5820.2A. Active LLW facilities in Solid Waste Storage Area (SWSA) 6 include Tumulus I and Tumulus II, the Interim Waste Management Facility (IWMF), LLW silos, high-range wells, asbestos silos, and fissile wells. The tumulus pads and IWMF are aboveground, high-strength concrete pads on which concrete vaults containing metal boxes of LLW are placed; the void space between the boxes and vaults is filled with grout. Eventually, these pads and vaults will be covered by an engineered multilayered cap. All other LLW facilities in SWSA 6 are below ground. In addition, this plan includes monitoring of the Hillcut Disposal Test Facility (HDTF) in SWSA 6, even though this facility was completed prior to the data of the DOE order. In SWSA 5 North, the TRU facilities include below-grade engineered caves, high-range wells, and unlined trenches. All samples from SWSA 6 are screened for alpha and beta activity, counted for gamma-emitting isotopes, and analyzed for tritium. In addition to these analytes, samples from SWSA 5 North are analyzed for specific transuranic elements.

  12. 21 CFR 131.157 - Light whipping cream.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Light whipping cream. 131.157 Section 131.157 Food... HUMAN CONSUMPTION MILK AND CREAM Requirements for Specific Standardized Milk and Cream § 131.157 Light whipping cream. (a) Description. Light whipping cream is cream which contains not less than 30 percent...

  13. 21 CFR 131.157 - Light whipping cream.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Light whipping cream. 131.157 Section 131.157 Food... HUMAN CONSUMPTION MILK AND CREAM Requirements for Specific Standardized Milk and Cream § 131.157 Light whipping cream. (a) Description. Light whipping cream is cream which contains not less than 30 percent...

  14. 21 CFR 131.157 - Light whipping cream.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Light whipping cream. 131.157 Section 131.157 Food... HUMAN CONSUMPTION MILK AND CREAM Requirements for Specific Standardized Milk and Cream § 131.157 Light whipping cream. (a) Description. Light whipping cream is cream which contains not less than 30 percent...

  15. 21 CFR 131.157 - Light whipping cream.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Light whipping cream. 131.157 Section 131.157 Food... HUMAN CONSUMPTION MILK AND CREAM Requirements for Specific Standardized Milk and Cream § 131.157 Light whipping cream. (a) Description. Light whipping cream is cream which contains not less than 30 percent...

  16. Heavy Metal Presence in Two Different Types of Ice Cream: Artisanal Ice Cream (Italian Gelato) and Industrial Ice Cream.

    PubMed

    Conficoni, D; Alberghini, L; Bissacco, E; Ferioli, M; Giaccone, V

    2017-03-01

    Ice cream, a popular product worldwide, is usually a milk-based product with other types of ingredients (fruit, eggs, cocoa, dried fruit, additives, and others). Different materials are used to obtain the desired taste, texture, consistency, and appearance of the final product. This study surveyed ice cream products available in Italy for heavy metals (lead, cadmium, chromium, tin, and arsenic). The differences between artisanal and industrial ice cream were also investigated because of the importance in the Italian diet and the diffusion of this ready-to-eat food. Ice cream sampling was performed between October 2010 and February 2011 in the northeast of Italy. A total of 100 samples were randomly collected from different sources: 50 industrial samples produced by 19 different brands were collected in coffee bars and supermarkets; 50 artisanal ice cream samples were gathered at nine different artisanal ice cream shops. Ten wooden sticks of industrial ice cream were analyzed in parallel to the ice cream. All samples were negative for arsenic and mercury. None of the artisanal ice cream samples were positive for lead and tin; 18% of the industrial ice cream samples were positive. All positive lead samples were higher than the legal limit stated for milk (0.02 mg/kg). All industrial ice cream samples were negative for cadmium, but cadmium was present in 10% of the artisanal ice cream samples. Chromium was found in 26% of the artisanal and in 58% of the industrial ice cream samples. The heavy metals found in the wooden sticks were different from the corresponding ice cream, pointing out the lack of cross-contamination between the products. Considering the results and the amount of ice cream consumed during the year, contamination through ice cream is a low risk for the Italian population, even though there is need for further analysis.

  17. Regenerable activated bauxite adsorbent alkali monitor probe

    DOEpatents

    Lee, Sheldon H. D.

    1992-01-01

    A regenerable activated bauxite adsorber alkali monitor probe for field applications to provide reliable measurement of alkali-vapor concentration in combustion gas with special emphasis on pressurized fluidized-bed combustion (PFBC) off-gas. More particularly, the invention relates to the development of a easily regenerable bauxite adsorbent for use in a method to accurately determine the alkali-vapor content of PFBC exhaust gases.

  18. [A monitor of the biomechanical cardiac activity].

    PubMed

    Masloboev, Iu P; Okhritskiĭ, A A; Prilutskiĭ, D A; Selishchev, S V

    2004-01-01

    A monitor of the biomechanical cardiac activity is described, which was elaborated on the basis of the accelerometer sensor and sigma-delta ADC for the purpose of registering the ballistocardiograms and seismocardiograms. The device ensures a non-stop signal recording for as long as 8 hours with the data being preserved in an inbuilt memory. Data are fed to the computer through the USB port. An algorithm is suggested for recordings processing by using the neuron-net technologies.

  19. Regenerable activated bauxite adsorbent alkali monitor probe

    SciTech Connect

    Lee, S.H.D.

    1991-01-22

    This invention relates to a regenerable activated bauxite adsorber alkali monitor probe for field applications to provide reliable measurement of alkali-vapor 5 concentration in combustion gas with special emphasis on pressurized fluidized-bed combustion (PFBC) off-gas. More particularly, the invention relates to the development of a easily regenerable bauxite adsorbent for use in a method to accurately determine the alkali-vapor content of PFBC 10 exhaust gases.

  20. Regenerable activated bauxite adsorbent alkali monitor probe

    DOEpatents

    Lee, S.H.D.

    1992-12-22

    A regenerable activated bauxite adsorber alkali monitor probe for field applications to provide reliable measurement of alkali-vapor concentration in combustion gas with special emphasis on pressurized fluidized-bed combustion (PFBC) off-gas. More particularly, the invention relates to the development of a easily regenerable bauxite adsorbent for use in a method to accurately determine the alkali-vapor content of PFBC exhaust gases. 6 figs.

  1. 7 CFR 58.715 - Cream, plastic cream and anhydrous milkfat.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Cream, plastic cream and anhydrous milkfat. 58.715 Section 58.715 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... Service 1 Quality Specifications for Raw Material § 58.715 Cream, plastic cream and anhydrous...

  2. 7 CFR 58.715 - Cream, plastic cream and anhydrous milkfat.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Cream, plastic cream and anhydrous milkfat. 58.715 Section 58.715 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... Service 1 Quality Specifications for Raw Material § 58.715 Cream, plastic cream and anhydrous...

  3. 7 CFR 58.715 - Cream, plastic cream and anhydrous milkfat.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Cream, plastic cream and anhydrous milkfat. 58.715 Section 58.715 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... Service 1 Quality Specifications for Raw Material § 58.715 Cream, plastic cream and anhydrous...

  4. 7 CFR 58.715 - Cream, plastic cream and anhydrous milkfat.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Cream, plastic cream and anhydrous milkfat. 58.715 Section 58.715 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... Service 1 Quality Specifications for Raw Material § 58.715 Cream, plastic cream and anhydrous...

  5. 7 CFR 58.715 - Cream, plastic cream and anhydrous milkfat.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Cream, plastic cream and anhydrous milkfat. 58.715 Section 58.715 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... Service 1 Quality Specifications for Raw Material § 58.715 Cream, plastic cream and anhydrous...

  6. Activity monitor accuracy in persons using canes.

    PubMed

    Wendland, Deborah Michael; Sprigle, Stephen H

    2012-01-01

    The StepWatch activity monitor has not been validated on multiple indoor and outdoor surfaces in a population using ambulation aids. The aims of this technical report are to report on strategies to configure the StepWatch activity monitor on subjects using a cane and to report the accuracy of both leg-mounted and cane-mounted StepWatch devices on people ambulating over different surfaces while using a cane. Sixteen subjects aged 67 to 85 yr (mean 75.6) who regularly use a cane for ambulation participated. StepWatch calibration was performed by adjusting sensitivity and cadence. Following calibration optimization, accuracy was tested on both the leg-mounted and cane-mounted devices on different surfaces, including linoleum, sidewalk, grass, ramp, and stairs. The leg-mounted device had an accuracy of 93.4% across all surfaces, while the cane-mounted device had an aggregate accuracy of 84.7% across all surfaces. Accuracy of the StepWatch on the stairs was significantly less accurate (p < 0.001) when comparing surfaces using repeated measures analysis of variance. When monitoring community mobility, placement of a StepWatch on a person and his/her ambulation aid can accurately document both activity and device use.

  7. 7 CFR 58.327 - Frozen cream.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Specifications for Dairy Plants Approved for USDA Inspection and Grading Service 1 Quality Specifications for Raw Material § 58.327 Frozen cream. To produce frozen cream eligible for official certification, the quality...

  8. 7 CFR 58.327 - Frozen cream.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Specifications for Dairy Plants Approved for USDA Inspection and Grading Service 1 Quality Specifications for Raw Material § 58.327 Frozen cream. To produce frozen cream eligible for official certification, the quality...

  9. 7 CFR 58.327 - Frozen cream.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Specifications for Dairy Plants Approved for USDA Inspection and Grading Service 1 Quality Specifications for Raw Material § 58.327 Frozen cream. To produce frozen cream eligible for official certification, the quality...

  10. 7 CFR 58.327 - Frozen cream.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Specifications for Dairy Plants Approved for USDA Inspection and Grading Service 1 Quality Specifications for Raw Material § 58.327 Frozen cream. To produce frozen cream eligible for official certification, the quality...

  11. In-vivo diagnosis and non-inasive monitoring of Imiquimod 5% cream for non-melanoma skin cancer using confocal laser scanning microscopy

    NASA Astrophysics Data System (ADS)

    Dietterle, S.; Lademann, J.; Röwert-Huber, H.-J.; Stockfleth, E.; Antoniou, C.; Sterry, W.; Astner, S.

    2008-10-01

    Basal cell carcinoma (BCC) is the most common cutaneous malignancy with increasing incidence rates worldwide. A number of established treatments are available, including surgical excision. The emergence of new non-invasive treatment modalities has prompted the development of non-invasive optical devices for therapeutic monitoring and evaluating treatment efficacy. This study was aimed to evaluate the clinical applicability of a fluorescence confocal laser scanning microscope (CFLSM) for non-invasive therapeutic monitoring of basal cell carcinoma treated with Imiquimod (Aldara®) as topical immune-response modifier. Eight participants with a diagnosis of basal cell carcinoma (BCC) were enrolled in this investigation. Sequential evaluation during treatment with Imiquimod showed progressive normalization of the confocal histomorphologic parameters in correlation with normal skin. Confocal laser scanning microscopy was able to identify characteristic features of BCC and allowed the visualization of therapeutic effects over time. Thus our results indicate the clinical applicability of CFLSM imaging to evaluate treatment efficacy in vivo and non-invasively.

  12. 7 CFR 58.326 - Plastic cream.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Plastic cream. 58.326 Section 58.326 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Material § 58.326 Plastic cream. To produce plastic cream eligible for official certification, the...

  13. 7 CFR 58.326 - Plastic cream.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Plastic cream. 58.326 Section 58.326 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Material § 58.326 Plastic cream. To produce plastic cream eligible for official certification, the...

  14. 7 CFR 58.326 - Plastic cream.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Plastic cream. 58.326 Section 58.326 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Material § 58.326 Plastic cream. To produce plastic cream eligible for official certification, the...

  15. 7 CFR 58.326 - Plastic cream.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Plastic cream. 58.326 Section 58.326 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Material § 58.326 Plastic cream. To produce plastic cream eligible for official certification, the...

  16. 21 CFR 524.520 - Cuprimyxin cream.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Cuprimyxin cream. 524.520 Section 524.520 Food and... cream. (a) Specifications. The drug contains 0.5 percent cuprimyxin (6-methoxy-1-phenazinol 5, 10-dioxide, cupric complex) in an aqueous cream base. (b) Sponsor. See No. 063238 in § 510.600(c) of...

  17. 7 CFR 58.322 - Cream.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Cream. 58.322 Section 58.322 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections....322 Cream. Cream separated at an approved plant and used for the manufacture of butter shall have...

  18. 21 CFR 524.2483 - Triamcinolone cream.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Triamcinolone cream. 524.2483 Section 524.2483 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Triamcinolone cream. (a) Specifications. The vanishing cream contains 0.1 percent triamcinolone acetonide....

  19. 21 CFR 524.2350 - Tolnaftate cream.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Tolnaftate cream. 524.2350 Section 524.2350 Food... Tolnaftate cream. (a) Specifications. The drug contains 1 percent tolnaftate (2-naphthyl-N-methyl-N-(3-tolyl) thionocarbamate) in an anhydrous cream base. (b) Sponsor. See No. 000061 in § 510.600(c) of this chapter....

  20. Stability conditions and mechanism of cream soaps: role of glycerol.

    PubMed

    Sagitani, Hiromichi

    2014-01-01

    Fatty acids, fatty acid potassium soaps, glycerol and water are essential ingredients in the production of stable cream soaps. In this study, the behavior of these components in solution was investigated to elucidate the stability conditions and mechanism of cream soaps. It was determined that the cream soaps were a dispersion of 1:1 acid soap (1:1 molar ratio of potassium soap/fatty acid) crystals in the lamellar gel phase, which has confirmed from the phase behavior diagrams and small angle X-ray scattering data. Glycerol was crucial ingredient in the formation of the lamellar gel phase. The cleansing process of the cream soaps was also evaluated using the same diagrams. The structure of the continuous phase in cream soaps changed from lamellar gel to a micellar aqueous solution upon the addition of water. This structural change during the washing process is important in producing the foaming activity of acid soaps to wash away dirt or excess fats from the skin surface.

  1. Tea creaming in nonfermented teas from Camellia sinensis and Ilex vomitoria.

    PubMed

    Kim, Youngmok; Talcott, Stephen T

    2012-11-28

    Tea creaming is the development of a cloudy or hazy appearance in tea and ready-to-drink tea products on cooling and is highly undesirable in the tea beverage industry. Commonly associated with fermented black or oolong teas, the objective of this study was to investigate the physicochemical mechanism of the formation of tea cream in nonfermented green tea (Camellia sinensis) and a caffeine-containing botanical tea from yaupon holly (Ilex vomitoria) that is free of catechin-based polyphenolics. Four tea-creaming activators (phenolics, soluble protein, caffeine, and metal ions) were added to tea infusions as well as decaffeinated teas created by chloroform extraction. Tea-creaming activators increased the weight and turbidity of both teas with the exception of soluble protein addition (as bovine serum albumin) to green tea, whereas the greatest increase in turbidity occurred with the addition of metal ions in green tea. Tea creaming was equally developed at three incubation temperatures (4, 25, and 40 °C) in both teas, but tea-creaming compositions in each tea were different at the incubating temperatures. The antioxidant capacity of each tea was lowered after creaming due to the loss of antioxidants that participated in tea cream formation.

  2. System and method for monitoring cellular activity

    NASA Technical Reports Server (NTRS)

    Bearman, Gregory H. (Inventor); Fraser, Scott E. (Inventor); Lansford, Russell D. (Inventor)

    2004-01-01

    A system and method for monitoring cellular activity in a cellular specimen. According to one embodiment, a plurality of excitable markers are applied to the specimen. A multi-photon laser microscope is provided to excite a region of the specimen and cause fluorescence to be radiated from the region. The radiating fluorescence is processed by a spectral analyzer to separate the fluorescence into respective wavelength bands. The respective bands of fluorescence are then collected by an array of detectors, with each detector receiving a corresponding one of the wavelength bands.

  3. System and method for monitoring cellular activity

    NASA Technical Reports Server (NTRS)

    Bearman, Gregory H. (Inventor); Fraser, Scott E. (Inventor); Lansford, Russell D. (Inventor)

    2002-01-01

    A system and method for monitoring cellular activity in a cellular specimen. According to one embodiment, a plurality of excitable markers are applied to the specimen. A multi-photon laser microscope is provided to excite a region of the specimen and cause fluorescence to be radiated from the region. The radiating fluorescence is processed by a spectral analyzer to separate the fluorescence into respective wavelength bands. The respective bands of fluorescence are then collected by an array of detectors, with each detector receiving a corresponding one of the wavelength bands.

  4. The Coffee and Cream Dilemma

    NASA Astrophysics Data System (ADS)

    Minor, Brandon; Feldman, Gerald

    2011-10-01

    Many coffee drinkers take cream with their coffee and often wonder whether to add the cream earlier or later. With the objective of keeping their coffee as hot as possible over a moderate time period (10-15 minutes), this is a question that most of them can never answer definitively. We investigated this problem empirically using hot and cold water, with special emphasis on the calorimetry of the mixture. Assuming a coffee:cream (hot:cold) ratio of 3:1, we began with two identical styrofoam coffee cups containing hot water and then added cold water at t = 200 s in one cup and t = 700 s in the other cup. Using two Vernier temperature probes to simultaneously track the temperature change during the cool-down period of the water in both cups over δt = 1000 s, we obtained a real-time graphical account of which process achieved the higher temperature over this time period. In addition, the effect of evaporation was explored by comparing trials with and without a lid on the coffee cup. The application of Newton's Law of Cooling, as compared to the graphical temperature data acquired, will leave no doubt as to the best strategy for adding cool cream to hot coffee.

  5. The effect of ice-cream-scoop water on the hygiene of ice cream.

    PubMed

    Wilson, I G; Heaney, J C; Weatherup, S T

    1997-08-01

    A survey of unopened ice cream, ice cream in use, and ice-cream-scoop water (n = 91) was conducted to determine the effect of scoop water hygiene on the microbiological quality of ice cream. An aerobic plate count around 10(6) c.f.u. ml-1 was the modal value for scoop waters. Unopened ice creams generally had counts around 10(3)-10(4) c.f.u. ml-1 and this increased by one order of magnitude when in use. Many scoop waters had low coliform counts, but almost half contained > 100 c.f.u. ml-1. E. coli was isolated in 18% of ice creams in use, and in 10% of unopened ice creams. S. aureus was not detected in any sample. Statistical analysis showed strong associations between indicator organisms and increased counts in ice cream in use. EC guidelines for indicator organisms in ice cream were exceeded by up to 56% of samples.

  6. Enhancing the functional properties and nutritional quality of ice cream with processed amla (Indian gooseberry).

    PubMed

    Goraya, Rajpreet Kaur; Bajwa, Usha

    2015-12-01

    Amla (Indian gooseberry) and its processed products are rich source of vitamin C, phenols, dietary fibre and antioxidants. In contrast, ice cream is a poor source of these phytochemicals and antioxidants; therefore, the present investigation was undertaken to enhance the functional properties and nutritional quality of ice cream with the incorporation of processed amla. Ice cream was prepared using amla shreds, pulp, preserve and candy at 5 to 20 % and powder at 0.5 to 2.0 % levels in ice cream mix prior to freezing. Inclusion of amla products at augmented levels resulted in significant changes in physico-chemical properties and phytochemical content of ice cream. The total solids decreased on addition of shreds and pulp and increased with preserve, candy and powder in ice cream at increasing levels. The functional constituents i.e. fibre, total phenols, tannins, ascorbic acid and antioxidant activity increased with greater level of inclusion. Incorporation of processed amla raised the melting resistance of ice cream and decreased the overrun. The samples with 5 % shreds and pulp, 10 % preserve and candy and 0.5 % powder were found to have highest overall acceptability scores. Inclusion of amla in all the forms i.e. shreds, pulp, preserve, candy and powder enhanced the functional properties and nutritional value of ice cream.

  7. In vivo irritation study of Melastoma malabathricum cream formulation on ICR mice

    NASA Astrophysics Data System (ADS)

    Yasin, Rabiahtul Adarwiyah Mohd; Jemon, Khairunadwa; Nor, Norefrina Shafinaz Md

    2016-11-01

    Melastoma malabathricum is a traditional herb that is used to treat wound on skin. It has also been proven to have antiviral activity against Herpes Simplex virus type 1 (HSV-1). In this study, M. malabathricum cream formulation was developed by incorporating M. malabathricum aqueous extract into cream base. The safety and biocompatibility of the formulated cream was investigated by topically applying the cream onto the back of ICR mice skin. Treatment with M. malabathricum was found to accelerate wound contraction with less scar formation. The effect of M. malabathricum has prompted a possibility that M. malabathricum might contribute in enhancing the healing process of cutaneous lesion caused by HSV-1. The formulated cream did not cause any skin irritation or adverse effect to ICR mice when topically applied within seven days of exposure.

  8. Sexual abuse and anti-wrinkle cream: evidence from octocrylene.

    PubMed

    Jamey, Carole; Tracqui, Antoine; Ludes, Bertrand

    2012-02-10

    We report an alleged case of sexual assault in which an anti-wrinkle cream could have been used as a lubricant. Three anorectal samples taken from the victim were given to us in an attempt to document the presence of remains of the cream involved. After examining the composition of the cream, octocrylene (OCT) was selected as the most relevant marker for this analysis. An ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was developed for identification of OCT. Anorectal samples were diluted with methanol and injected onto an Acquity BEH C18 column using a gradient mode with 0.1% formic acid/acetonitrile as the mobile phase. Data were acquired using positive electrospray ionization and multiple reaction monitoring. Three transitions were selected for OCT (m/z 362.2>250.0, m/z 362.2>232.0 and m/z 362.2>204.0). The analysis of the cream seized at the offender's home confirmed the presence of OCT as an ingredient, and the analysis of extracts from the anorectal samples also allowed the formal identification of OCT. These results strongly suggest that a cosmetic containing octocrylene as an ingredient has in fact been applied to the anus of the alleged victim.

  9. Moisturizing effect of stable cream containing Crocus sativus extracts.

    PubMed

    Akhtar, Naveed; Khan, Haji Muhammad-Shoaib; Ashraf, Shoaib; Mohammad, Imran Shair; Saqib, Najam-us; Bashir, Kamran

    2014-11-01

    The present study is about to prepare stable cream of water-in-oil emulsion containing extracts of Crocus sativus against its base (without extracts) taken as control, to determine its stability on different storage conditions and effects on skin moisture contents and transepidermal water loss. The formulation contains 3% Crocus sativus (Saffron) concentrated extracts, and the base containing no extract, were formulated. Different stability tests were done on samples, which placed at 8°C, 25°C, 40°C and 40°C with 75% relative humidity, for 4 week period. These formulations (Creams) were applied on the cheeks of human volunteers for 8week period. To evaluate any effect produced by these formulations different skin parameters were monitored every week. The significant results of this study explored the fact that water-in-oil emulsion topical cream of saffron formulated from Crocus sativus extract has absolute physical stability at different storage conditions. The increase in skin moisture contents and changes in transepidermal water loss were significant (p<0.05) with respect to base and formulation respectively. Topical cream of Crocus sativus showed significant moisturizing effects on human skin.

  10. Status and Plan of the ISS-CREAM Experiment

    NASA Astrophysics Data System (ADS)

    Picot-Clemente, Nicolas; Iss-Cream Collaboration

    2016-03-01

    The Cosmic Ray Energetics and Mass (CREAM) project began as a balloon-borne experiment, which was flown successfully for 161 days in six flights over Antarctica. It was subsequently reconfigured for implementation on the International Space Station (ISS) to provide an order of magnitude increase in the exposure time with no atmospheric overburden. The ISS-CREAM instrument is configured of four subsystems: four layers of silicon charge detector (SCD) for charge measurements, top and bottom counting detectors (TCD/BCD) for electron/proton separation, a calorimeter (CAL) for energy measurements, and a boronated scintillator detector (BSD) for additional electron/proton distinction. CREAM is designed to investigate cosmic-ray origin, acceleration, and propagation by directly measuring individual particles with energy between 1012-1015eV and determining cosmic ray composition from protons to iron. The hardware was successfully tested, and remote monitoring and control capabilities were verified. It is scheduled for launch in 2016. The status and plan of the ISS-CREAM experiment will be presented.

  11. Quality Assurance Project Plan for Facility Effluent Monitoring Plan activities

    SciTech Connect

    Frazier, T.P.

    1994-10-20

    This Quality Assurance Project Plan addresses the quality assurance requirements for the activities associated with the Facility Effluent Monitoring Plans, which are part of the overall Hanford Site Environmental Protection Plan. This plan specifically applies to the sampling and analysis activities and continuous monitoring performed for all Facility Effluent Monitoring Plan activities conducted by Westinghouse Hanford Company. It is generic in approach and will be implemented in conjunction with the specific requirements of the individual Facility Effluent Monitoring Plans.

  12. Multiwavelength monitoring of active galactic nuclei

    NASA Technical Reports Server (NTRS)

    Urry, C. M.

    1993-01-01

    Recent multiwavelength monitoring of active galactic nuclei (AGN), particularly with the IUE satellite, has produced extraordinay advances in our understanding of the energy-generation mechanism(s) in the central engine and of the structure of the surrounding material. Examples discussed here include both ordinary AGN and blazars (the collective name for highly variable, radio-loud AGN like BL Lac objects and Optically Violently Variable quasars). In the last decade, efforts to obtain single-epoch multiwavelength spectra led to fundamentally new models for the structure of AGN, involving accretion disks for AGN and relativistic jets for blazars. Recent extensions of multiwavelength spectroscopy into the temporal domain have shown that while these general pictures may be correct, the details were probably wrong. Campaigns to monitor Seyfert 1 galaxies like NGC 4151, NGC 5548 and Fairall 9 at infrared, optical, ultraviolet and X-ray wavelengths indicate that broad-emission line regions are stratified by ionization, density, and velocity; argue against a standard thin accretion disk model; and suggest that X-rays represent primary rather than reprocessed radiation. For blazars, years of radio monitoring indicated emission from an inhomogeneous synchrotron-emitting plasma, which could also produce at least some of the shorter-wavelength emission. The recent month-long campaign to observe the BL Lac object PKS 2155-304 has revealed remarkably rapid variability that extends from the infrared through the X-ray with similar amplitude and little or no discernible lag. This lends strong support to relativistic jet models and rules out the proposed accretion disk model for the ultraviolet-X-ray continuum.

  13. Monitoring of Crew Activity with FAMOS

    NASA Astrophysics Data System (ADS)

    Wolf, L.; Cajochen, C.; Bromundt, V.

    2007-10-01

    The success of long duration space missions, such as manned missions to Mars, depends on high and sustained levels of vigilance and performance of astronauts and operators working in the technology rich environment of a spacecraft. Experiment 'Monitoring of Crew Activity with FAMOS' was set up to obtain operational experience with complimentary methods / technologies to assess the alertness / sleepiness status of selected AustroMars crewmembers on a daily basis. We applied a neurobehavioral test battery consisting of 1) Karolinska Sleepiness Scale KSS, 2) Karolinska Drowsiness Test KDT, 3) Psychomotor Vigilance Task PVT, combined with 4) left eye video recordings with an early prototype of the FAMOS Fatigue Monitoring System headset currently being developed by Sowoon Technologies (CH), and 5) Actiwatches that were worn continuously. A test battery required approximately 15 minutes and was repeated up to 4 times daily by 2 to 4 subjects. Here we present the data analysis of methods 1, 2, 3, and 5, while data analysis of method 4 is still in progress.

  14. 21 CFR 131.162 - Acidified sour cream.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Acidified sour cream. 131.162 Section 131.162 Food... HUMAN CONSUMPTION MILK AND CREAM Requirements for Specific Standardized Milk and Cream § 131.162 Acidified sour cream. (a) Description. Acidified sour cream results from the souring of pasteurized...

  15. Active chaotic excitation for bolted joint monitoring

    NASA Astrophysics Data System (ADS)

    Fasel, Timothy R.; Todd, Michael D.; Park, Gyuhae

    2006-03-01

    Recent research has shown that high frequency chaotic excitation and state space reconstruction may be used to identify incipient damage (loss of preload) in a bolted joint. In this study, a new experiment is undertaken with updated test equipment, including a piezostack actuator that allows for precise control of bolt preload. The excitation waveform is applied to a macro-fiber composite (MFC) patch that is bonded to the test structure and is sensed in an active manner using a second MFC patch. A novel prediction error algorithm, based on comparing filtered properties of the guided chaotic waves, is used to determine the damage state of a frame structure and is shown to be highly sensitive to small levels of bolt preload loss. The performance of the prediction error method is compared with standard structural health monitoring damage features that are based on time series analysis using auto-regressive (AR) models.

  16. Ice recrystallization inhibition in ice cream as affected by ice structuring proteins from winter wheat grass.

    PubMed

    Regand, A; Goff, H D

    2006-01-01

    Ice recrystallization in quiescently frozen sucrose solutions that contained some of the ingredients commonly found in ice cream and in ice cream manufactured under commercial conditions, with or without ice structuring proteins (ISP) from cold-acclimated winter wheat grass extract (AWWE), was assessed by bright field microscopy. In sucrose solutions, critical differences in moisture content, viscosity, ionic strength, and other properties derived from the presence of other ingredients (skim milk powder, corn syrup solids, locust bean gum) caused a reduction in ice crystal growth. Significant ISP activity in retarding ice crystal growth was observed in all solutions (44% for the most complex mix) containing 0.13% total protein from AWWE. In heat-shocked ice cream, ice recrystallization rates were significantly reduced 40 and 46% with the addition of 0.0025 and 0.0037% total protein from AWWE. The ISP activity in ice cream was not hindered by its inclusion in mix prior to pasteurization. A synergistic effect between ISP and stabilizer was observed, as ISP activity was reduced in the absence of stabilizer in ice cream formulations. A remarkably smoother texture for ice creams containing ISP after heat-shock storage was evident by sensory evaluation. The efficiency of ISP from AWWE in controlling ice crystal growth in ice cream has been demonstrated.

  17. 7 CFR 1000.16 - Fluid cream product.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... cream), including sterilized cream, or a mixture of cream and milk or skim milk containing 9 percent or... Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING...

  18. Wrinkle Creams: Your Guide to Younger Looking Skin

    MedlinePlus

    Wrinkle creams: Your guide to younger looking skin Do over-the-counter wrinkle creams really reduce the appearance of fine lines and ... many factors. By Mayo Clinic Staff Many wrinkle creams and lotions sold in department stores, in drugstores ...

  19. An Automatic Tremor Activity Monitoring System (TAMS)

    NASA Astrophysics Data System (ADS)

    Kao, H.; Thompson, P. J.; Rogers, G.; Dragert, H.; Spence, G.

    2006-12-01

    We have developed an algorithm that quantitatively characterizes the level of seismic tremors from recorded seismic waveforms. For each hour of waveform at a given station, the process begins with the calculation of scintillation index and moving average with various time lengths. The scintillation index (essentially the `normalized variance of intensity of the signal') is adapted from the studies of pulses in radio waves and is an efficient tool to identify the energy bursts of tremor signals. Both scintillation index and moving average values are fed into a series of logic gates to determine if tremor activity exists. This algorithm is implemented in the Tremor Activity Monitoring System (TAMS) to provide automatic early alerts for episodic tremor and slip (ETS) events in the northern Cascadia margin. Currently, TAMS retrieves the digital waveforms recorded during the previous day from the Canadian National Seismographic Network (CNSN) archive server at 1 AM every morning. The detecting process is repeated for all stations and hours to determine the level of tremor activity of the previous day. If a sufficient number of stations within a radius of 100 km are determined to have tremor patterns and coherent tremor arrivals can be found at more than 3 stations, TAMS automatically sends out alert emails to a list of subscribers with a figure summarizing the hours and locations of coherent tremors. TAMS outputs are very consistent with the work done by visual inspection, especially for major ETS events. It is straightforward to configure TAMS into a near-real-time system that can send out hourly (or shorter) reports if necessary.

  20. How consumer physical activity monitors could transform human physiology research.

    PubMed

    Wright, Stephen P; Hall Brown, Tyish S; Collier, Scott R; Sandberg, Kathryn

    2017-03-01

    A sedentary lifestyle and lack of physical activity are well-established risk factors for chronic disease and adverse health outcomes. Thus, there is enormous interest in measuring physical activity in biomedical research. Many consumer physical activity monitors, including Basis Health Tracker, BodyMedia Fit, DirectLife, Fitbit Flex, Fitbit One, Fitbit Zip, Garmin Vivofit, Jawbone UP, MisFit Shine, Nike FuelBand, Polar Loop, Withings Pulse O2, and others have accuracies similar to that of research-grade physical activity monitors for measuring steps. This review focuses on the unprecedented opportunities that consumer physical activity monitors offer for human physiology and pathophysiology research because of their ability to measure activity continuously under real-life conditions and because they are already widely used by consumers. We examine current and potential uses of consumer physical activity monitors as a measuring or monitoring device, or as an intervention in strategies to change behavior and predict health outcomes. The accuracy, reliability, reproducibility, and validity of consumer physical activity monitors are reviewed, as are limitations and challenges associated with using these devices in research. Other topics covered include how smartphone apps and platforms, such as the Apple ResearchKit, can be used in conjunction with consumer physical activity monitors for research. Lastly, the future of consumer physical activity monitors and related technology is considered: pattern recognition, integration of sleep monitors, and other biosensors in combination with new forms of information processing.

  1. A System for Monitoring Posture and Physical Activity Using Accelerometers

    DTIC Science & Technology

    2007-11-02

    Abstract- Accelerometers can be used to monitor physical activity in the home over prolonged periods. We describe a novel system for...processing schema in which these parameters are extracted is described. Keywords - physical activity , accelerometers, congestive heart failure, chronic...When monitoring the condition of patients with neurodegenerative or chronic diseases, a knowledge of their body movement and physical activity

  2. Studies on the contraceptive efficacy of Praneem polyherbal cream.

    PubMed

    Garg, S; Taluja, V; Upadhyay, S N; Talwar, G P

    1993-12-01

    Praneem polyherbal cream, a spermicidal formulation, has been developed at the National Institute of Immunology, which makes use of Praneem, a purified extract from the dried seeds of an ancient Indian plant Azadirachta indica (Neem), extract from the pericarp of fruits of Sapindus species and quinine hydrochloride. These ingredients have a synergistic spermicidal activity and an optimised formula was derived. The components were made into a water-soluble cream base prepared by using pharmaceutically acceptable base and stabilised by addition of IP grade antioxidant and preservatives. The cream is devoid of irritation and sensitization potential, as seen with standard Draize test on normal and abraded skin of rabbits and by 21-day cumulative skin sensitivity in human volunteers. The formulation was found to be safe under subacute toxicity studies in monkeys. The formulation has shown high contraceptive efficacy in rabbits and in monkeys after intravaginal application. The shelf-life of the cream at room temperature is estimated to be 18 months by accelerated stability studies.

  3. Deformation Monitoring of AN Active Fault

    NASA Astrophysics Data System (ADS)

    Ostapchuk, A.

    2015-12-01

    The discovery of low frequency earthquakes, slow slip events and other deformation phenomena, new for geophysics, change our understanding of how the energy accumulated in the Earth's crust do release. The new geophysical data make one revise the underlying mechanism of geomechanical processes taking place in fault zones. Conditions for generating different slip modes are still unclear. The most vital question is whether a certain slip mode is intrinsic for a fault or may be controlled by external factors. This work presents the results of two and a half year deformation monitoring of a discontinuity in the zone of the Main Sayanskiy Fault. Main Sayanskiy Fault is right-lateral strike-slip fault. Observations were performed in the tunnel of Talaya seismic station (TLY), Irkutsk region, Russia. Measurements were carried out 70 m away from the entrance of the tunnel, the thickness of overlying rock was about 30 m. Inductive sensors of displacement were mounted at the both sides of a discontinuity, which recorded three components of relative fault side displacement with the accuracy of 0.2 mcm. Temperature variation inside the tunnel didn't exceed 0.5oC during the all period of observations. Important information about deformation properties of an active fault was obtained. A pronounced seasonality of deformation characteristics of discontinuity is observed in the investigated segment of rock. A great number of slow slip events with durations from several hours to several weeks were registered. Besides that alterations of fault deformation characteristics before the megathrust earthquake M9.0 Tohoku Oki 11 March 2011 and reaction to the event itself were detected. The work was supported by the Russian Science Foundation (grant no. 14-17-00719).

  4. 7 CFR 58.348 - Plastic cream.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Plastic cream. 58.348 Section 58.348 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Products Bearing Usda Official Identification § 58.348 Plastic cream. The flavor shall be sweet,...

  5. 7 CFR 58.348 - Plastic cream.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Plastic cream. 58.348 Section 58.348 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Products Bearing Usda Official Identification § 58.348 Plastic cream. The flavor shall be sweet,...

  6. 7 CFR 58.348 - Plastic cream.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Plastic cream. 58.348 Section 58.348 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Products Bearing Usda Official Identification § 58.348 Plastic cream. The flavor shall be sweet,...

  7. 7 CFR 58.348 - Plastic cream.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Plastic cream. 58.348 Section 58.348 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Products Bearing Usda Official Identification § 58.348 Plastic cream. The flavor shall be sweet,...

  8. 7 CFR 58.349 - Frozen cream.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Frozen cream. 58.349 Section 58.349 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Products Bearing Usda Official Identification § 58.349 Frozen cream. The flavor shall be sweet,...

  9. 7 CFR 58.348 - Plastic cream.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Plastic cream. 58.348 Section 58.348 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Products Bearing Usda Official Identification § 58.348 Plastic cream. The flavor shall be sweet,...

  10. Geophysical Mapping and Monitoring of Active Planets (GMAP)

    NASA Astrophysics Data System (ADS)

    McGovern, P. J.; Goossens, S. J.; Lemoine, F. G.

    2017-02-01

    Recent findings require a strongly upward revision of volcano-tectonic activity rate estimates for Venus and Mars. We propose a program of Geophysical Mapping and Monitoring of Active Planets (GMAP) including seismology, gravimetry, InSAR, and GPS.

  11. Instructional physical activity monitor video in english and spanish

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The ActiGraph activity monitor is a widely used method for assessing physical activity. Compliance with study procedures in critical. A common procedure is for the research team to meet with participants and demonstrate how and when to attach and remove the monitor and convey how many wear-days are ...

  12. Quality Assurance Project Plan for Facility Effluent Monitoring Plan activities

    SciTech Connect

    Nickels, J.M.

    1991-06-01

    This Quality Assurance Project Plan addresses the quality assurance requirements for the Facility Monitoring Plans of the overall site-wide environmental monitoring plan. This plan specifically applies to the sampling and analysis activities and continuous monitoring performed for all Facility Effluent Monitoring Plan activities conducted by Westinghouse Hanford Company. It is generic in approach and will be implemented in conjunction with the specific requirements of individual Facility Effluent Monitoring Plans. This document is intended to be a basic road map to the Facility Effluent Monitoring Plan documents (i.e., the guidance document for preparing Facility Effluent Monitoring Plans, Facility Effluent Monitoring Plan determinations, management plan, and Facility Effluent Monitoring Plans). The implementing procedures, plans, and instructions are appropriate for the control of effluent monitoring plans requiring compliance with US Department of Energy, US Environmental Protection Agency, state, and local requirements. This Quality Assurance Project Plan contains a matrix of organizational responsibilities, procedural resources from facility or site manuals used in the Facility Effluent Monitoring Plans, and a list of the analytes of interest and analytical methods for each facility preparing a Facility Effluent Monitoring Plan. 44 refs., 1 figs., 2 tabs.

  13. Remote Physical Activity Monitoring in Neurological Disease: A Systematic Review

    PubMed Central

    Block, Valerie A. J.; Pitsch, Erica; Tahir, Peggy; Cree, Bruce A. C.; Allen, Diane D.; Gelfand, Jeffrey M.

    2016-01-01

    Objective To perform a systematic review of studies using remote physical activity monitoring in neurological diseases, highlighting advances and determining gaps. Methods Studies were systematically identified in PubMed/MEDLINE, CINAHL and SCOPUS from January 2004 to December 2014 that monitored physical activity for ≥24 hours in adults with neurological diseases. Studies that measured only involuntary motor activity (tremor, seizures), energy expenditure or sleep were excluded. Feasibility, findings, and protocols were examined. Results 137 studies met inclusion criteria in multiple sclerosis (MS) (61 studies); stroke (41); Parkinson's Disease (PD) (20); dementia (11); traumatic brain injury (2) and ataxia (1). Physical activity levels measured by remote monitoring are consistently low in people with MS, stroke and dementia, and patterns of physical activity are altered in PD. In MS, decreased ambulatory activity assessed via remote monitoring is associated with greater disability and lower quality of life. In stroke, remote measures of upper limb function and ambulation are associated with functional recovery following rehabilitation and goal-directed interventions. In PD, remote monitoring may help to predict falls. In dementia, remote physical activity measures correlate with disease severity and can detect wandering. Conclusions These studies show that remote physical activity monitoring is feasible in neurological diseases, including in people with moderate to severe neurological disability. Remote monitoring can be a psychometrically sound and responsive way to assess physical activity in neurological disease. Further research is needed to ensure these tools provide meaningful information in the context of specific neurological disorders and patterns of neurological disability. PMID:27124611

  14. 7 CFR 58.321 - Cream storage tanks.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Cream storage tanks. 58.321 Section 58.321 Agriculture....321 Cream storage tanks. Cream storage tanks shall meet the requirements of § 58.128(d). Cream storage tanks for continuous churns should be equipped with effective temperature controls and recording...

  15. 7 CFR 58.649 - Physical requirements for ice cream.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Physical requirements for ice cream. 58.649 Section 58... requirements for ice cream. (a) Flavor. The flavor of the finished ice cream shall be pleasing and desirable, and characteristic of the fresh milk and cream and the particular flavoring used. (b) Body and...

  16. 21 CFR 135.110 - Ice cream and frozen custard.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Ice cream and frozen custard. 135.110 Section 135....110 Ice cream and frozen custard. (a) Description. (1) Ice cream is a food produced by freezing, while... accomplish specific functions. Ice cream is sweetened with safe and suitable sweeteners and may...

  17. 7 CFR 58.321 - Cream storage tanks.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Cream storage tanks. 58.321 Section 58.321 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....321 Cream storage tanks. Cream storage tanks shall meet the requirements of § 58.128(d). Cream...

  18. 21 CFR 133.134 - Cream cheese with other foods.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Cream cheese with other foods. 133.134 Section 133... Cheese and Related Products § 133.134 Cream cheese with other foods. (a) Description. Cream cheese with other foods is the class of foods prepared by mixing, with or without the aid of heat, cream cheese...

  19. Cosmic Ray Energetics and Mass (CREAM)

    NASA Technical Reports Server (NTRS)

    Coutu, Stephane

    2005-01-01

    The CREAM instrument was flown on a Long Duration Balloon in Antarctica in December 2004 and January 2005, achieving a flight duration record of nearly 42 days. It detected and recorded cosmic ray primary particles ranging in type from hydrogen to iron nuclei and in energy from 1 TeV to several hundred TeV. With the data collected we will have the world's best measurement of the energy spectra and mass composition of nuclei in the primary cosmic ray flux at these energies, close to the astrophysical knee . The instrument utilized a thin calorimeter, a transition radiation detector and a timing charge detector, which also provided time-of-flight information. The responsibilities of our group have been with the timing charge detector (TCD), and with the data acquisition electronics and ground station support equipment. The TCD utilized fast scintillators to measure the charge of the primary cosmic ray before any interactions could take place within the calorimeter. The data acquisition electronics handled the output of the various detectors, in a fashion fully integrated with the payload bus. A space-qualified flight computer controlled the acquisition, and was used for preliminary trigger information processing and decision making. Ground support equipment was used to monitor the health of the payload, acquire and archive the data transmitted to the ground, and to provide real-time control of the instrument in flight.

  20. Enrichment of functional properties of ice cream with pomegranate by-products.

    PubMed

    Çam, Mustafa; Erdoğan, Fatma; Aslan, Duygu; Dinç, Merve

    2013-10-01

    Pomegranate peel rich in phenolics, and pomegranate seed which contain a conjugated fatty acid namely punicic acid in lipid fraction remain as by-products after processing the fruit into juice. Ice cream is poor in polyunsaturated fatty acids and phenolics, therefore, this study was conducted to improve the functional properties of ice cream by incorporating pomegranate peel phenolics and pomegranate seed oil. Incorporation of the peel phenolics into ice cream at the levels of 0.1% and 0.4% (w/w) resulted in significant changes in the pH, total acidity, and color of the samples. The most prominent outcomes of phenolic incorporation were sharp improvements in antioxidant and antidiabetic activities as well as the phenolic content of ice creams. Replacement of pomegranate seed oil by milk fat at the levels of 2.0% and 4.0% (w/w) increased the conjugated fatty acid content. However, perception of oxidized flavor increased with the additional seed oil. When one considers the functional and nutritional improvements in the enrichment of the ice cream together with overall acceptability results of the sensory analysis, then it follows from this study that ice creams enriched with pomegranate peel phenolics up to 0.4% (w/w) and pomegranate seed oil up to 2.0% (w/w) could be introduced to markets as functional ice cream. Enrichment of ice creams with pomegranate by-products might provide consumers health benefits with striking functional properties of punicalagins in pomegranate peel, and punicic acid in pomegranate seed oil.

  1. Effect of cream fermentation on microbiological, physicochemical and rheological properties of L. helveticus-butter.

    PubMed

    Ewe, Joo-Ann; Loo, Su-Yi

    2016-06-15

    The primary objective of this study was to evaluate the physicochemical and rheological properties of butter produced by Lactobacillus helveticus fermented cream. The incorporation of putative probiotic - the L. helveticus, to ferment cream prior to butter production was anticipated to alter the nutritional composition of butter. Changes in crude macronutrients and the resultant modification relating to textural properties of butter induced upon metabolic activities of L. helveticus in cream were focused in this research. Fermented butter (LH-butter) was produced by churning the cream that was fermented by lactobacilli at 37 °C for 24 h. Physicochemical analysis, proximate analysis and rheology properties of LH-butter were compared with butter produced using unfermented cream (control). LH-butter showed a significantly (P<0.05) higher fat content and acid value; lower moisture and ash; and was softer than the control. Cream fermentation modified nutritional and textural properties of butter in which LH-butter contained higher health beneficial unsaturated fatty acids than the control and thus rendered the product softer. Its enrichment with probiotics could thus further enhance its functional property.

  2. Active Low Intrusion Hybrid Monitor for Wireless Sensor Networks

    PubMed Central

    Navia, Marlon; Campelo, Jose C.; Bonastre, Alberto; Ors, Rafael; Capella, Juan V.; Serrano, Juan J.

    2015-01-01

    Several systems have been proposed to monitor wireless sensor networks (WSN). These systems may be active (causing a high degree of intrusion) or passive (low observability inside the nodes). This paper presents the implementation of an active hybrid (hardware and software) monitor with low intrusion. It is based on the addition to the sensor node of a monitor node (hardware part) which, through a standard interface, is able to receive the monitoring information sent by a piece of software executed in the sensor node. The intrusion on time, code, and energy caused in the sensor nodes by the monitor is evaluated as a function of data size and the interface used. Then different interfaces, commonly available in sensor nodes, are evaluated: serial transmission (USART), serial peripheral interface (SPI), and parallel. The proposed hybrid monitor provides highly detailed information, barely disturbed by the measurement tool (interference), about the behavior of the WSN that may be used to evaluate many properties such as performance, dependability, security, etc. Monitor nodes are self-powered and may be removed after the monitoring campaign to be reused in other campaigns and/or WSNs. No other hardware-independent monitoring platforms with such low interference have been found in the literature. PMID:26393604

  3. Active Low Intrusion Hybrid Monitor for Wireless Sensor Networks.

    PubMed

    Navia, Marlon; Campelo, Jose C; Bonastre, Alberto; Ors, Rafael; Capella, Juan V; Serrano, Juan J

    2015-09-18

    Several systems have been proposed to monitor wireless sensor networks (WSN). These systems may be active (causing a high degree of intrusion) or passive (low observability inside the nodes). This paper presents the implementation of an active hybrid (hardware and software) monitor with low intrusion. It is based on the addition to the sensor node of a monitor node (hardware part) which, through a standard interface, is able to receive the monitoring information sent by a piece of software executed in the sensor node. The intrusion on time, code, and energy caused in the sensor nodes by the monitor is evaluated as a function of data size and the interface used. Then different interfaces, commonly available in sensor nodes, are evaluated: serial transmission (USART), serial peripheral interface (SPI), and parallel. The proposed hybrid monitor provides highly detailed information, barely disturbed by the measurement tool (interference), about the behavior of the WSN that may be used to evaluate many properties such as performance, dependability, security, etc. Monitor nodes are self-powered and may be removed after the monitoring campaign to be reused in other campaigns and/or WSNs. No other hardware-independent monitoring platforms with such low interference have been found in the literature.

  4. Photocardiography: a novel method for monitoring cardiac activity in fish.

    PubMed

    Yoshida, Masayuki; Hirano, Ruriko; Shima, Takao

    2009-05-01

    A non-invasive technique to monitor cardiac activity in small fish, such as goldfish, zebrafish, and medaka, is needed. In the present study, we developed photocardiography (PCG), a non-invasive optical method, to record cardiac activity in small fish. The method monitors changes in near-infrared light transmission through the heart using a phototransistor located outside the body. With this technique, heartbeats in fish of various sizes (14-218 mm) were stably recorded. PCG was applied to monitor the heartbeat during fear-related classical heart rate conditioning in goldfish wherein an electrical shock was used as an unconditioned stimulus. The heartbeats were continuously monitored, even when the beat coincided with the electrical shock, showing that PCG is robust even in an electrically noisy environment. This technique is particularly useful when monitoring the heartbeats of fish of small size or in the presence of ambient electrical noise, conditions in which the use of conventional electrocardiography (ECG) is difficult.

  5. Does alprostadil cream hit the spot?

    PubMed

    2015-02-01

    Alprostadil, a prostaglandin, has been marketed for many years as a urethral stick and an intracavernous injection for the treatment of erectile dysfunction.(1) It is now available in the form of a cream (Vitaros-Takeda). Adverts for the product declare: "Sex with no pills, pellets or needles. Spot on." In this article, we consider the evidence for alprostadil cream, and its place in the management of erectile dysfunction.

  6. Construction monitoring activities in the ESF starter tunnel

    SciTech Connect

    Pott, J.; Carlisle, S.

    1994-05-01

    In situ design verification activities am being conducted in the North Ramp Starter Tunnel of the Yucca Mountain Project Exploratory Studies Facility. These activities include: monitoring the peak particle velocities and evaluating the damage to the rock mass associated with construction blasting, assessing the rock mass quality surrounding the tunnel, monitoring the performance of the installed ground support, and monitoring the stability of the tunnel. In this paper, examples of the data that have been collected and preliminary conclusions from the data are presented.

  7. Bigelow Expandable Activity Module (BEAM) Monitoring System

    NASA Technical Reports Server (NTRS)

    Wells, Nathan

    2017-01-01

    What is Bigelow Expandable Activity Module (BEAM)? The Bigelow Expandable Activity Module (BEAM) is an expandable habitat technology demonstration on ISS; increase human-rated inflatable structure Technology Readiness Level (TRL) to level 9. NASA managed ISS payload project in partnership with Bigelow Aerospace. Launched to ISS on Space X 8 (April 8th, 2016). Fully expanded on May 28th, 2016. Jeff Williams/Exp. 48 Commander first entered BEAM on June 5th, 2016.

  8. Changes in psychrotrophic microbial populations during milk creaming to produce Grana Trentino cheese.

    PubMed

    Franciosi, Elena; De Sabbata, Giorgia; Gardini, Fausto; Cavazza, Agostino; Poznanski, Elisa

    2011-02-01

    The aim of this study was to study the psychrotrophic microbiota developing during milk creaming of Grana Trentino cheese-making. 138 isolates from raw whole milk, cream and skim milk samples were screened by Randomly amplified polymorphic DNA PCR biotyping and representative strains of each biotype were characterised by partial 16S rRNA gene sequencing and enzymatic activity. Pseudomonadaceae were commonly isolated in cream samples while Streptococcaceae and Enterobacteriaceae in milk samples. Moraxellaceae and Flavobacteriaceae were found in both cream and milk samples. More than 80% of psychrotrophic isolates could grow at 37°C. All Flavobacteriaceae and half of Pseudomonadaceae biotypes displayed proteolytic activity on milk agar even at low temperatures such as 10°C. All Streptococcaceae and some of Enterobacteriaceae displayed acidifying activity and almost all Acinetobacter spp. (Moraxellaceae) displayed lipolytic activity towards tributyrin. Even if psychrotrophic bacteria is not the dominant microbial group in raw milk, their total number increases during creaming and becomes one of the most present group together with Lactic Acid Bacteria. Their enzymatic activities may be key players in determining milk quality for cheese making.

  9. Efficacy and Safety of Cream Containing Climbazole/Piroctone Olamine for Facial Seborrheic Dermatitis: A Single-Center, Open-Label Split-Face Clinical Study

    PubMed Central

    Youn, Hae Jeong; Kim, Soo Young; Park, Minji; Jung, Won Hee; Choe, Yong Beom; Ahn, Kyu Joong

    2016-01-01

    Background Seborrheic dermatitis (SD) is a multifactorial disease; Malassezia species play an important role in its pathogenesis. Objective We aimed to determine whether a cream containing climbazole/piroctone olamine (C/P cream), antifungal agents with expected efficacy against Malassezia species, could improve SD symptoms. Methods We instructed 24 patients with mild-to-moderate SD to apply the C/P cream and emollient cream on the right and left sides of the face, respectively, every morning and evening for 4 weeks. The casual sebum level (measured with Sebumeter®; Courage & Khazaka Electronic GmbH, Germany) and the extent of erythema (measured with Mexameter®; Courage & Khazaka Electronic GmbH) on the face were measured at baseline and after 4 weeks. The minimal inhibitory concentration (MIC) was determined to demonstrate the antifungal activity of the C/P cream. Results The casual sebum level and erythema were measured at week 4, and the median values demonstrated a quantitative improvement on the C/P cream-treated right side of the face compared to the emollient cream-treated left side. For the C/P cream, the MICs were 0.625, 5, 0.625, and 2.5 mg/ml for Malassezia restricta, M. globosa, M. sympodialis, and M. slooffiae, respectively. Conclusion Based on the reduced casual sebum level and extent of erythema, the antifungal activity of C/P cream against Malassezia species seems useful for the treatment of mild to moderate SD. PMID:27904273

  10. ESR/spin probe study of ice cream.

    PubMed

    Gillies, Duncan G; Greenley, Katherine R; Sutcliffe, Leslie H

    2006-07-12

    Spin probes based on the 1,1,3,3-tetramethylisoindolin-2-yl structure have been used, in conjunction with electron spin resonance spectroscopy (ESR), to study the physical changes occurring in ice cream during freezing and melting. The ESR measurements allowed the rotational correlation times, tau(B), of the spin probes to be determined. Two probes were used together in a given sample of ice cream, namely, 1,1,3,3-tetramethylisoindolin-2-yl (TMIO), which samples the fat phase, and the sodium salt of 1,1,3,3-tetramethylisoindolin-2-yloxyl-5-sulfonate (NaTMIOS), which samples the aqueous phase. Data from the TMIO probe showed that when ice cream is cooled, the fat phase is a mixture of solid and liquid fat until a temperature of approximately -60 degrees C is reached. The water-soluble probe NaTMIOS showed that the aqueous phase changes completely from liquid to solid within 1 degrees C of -18 degrees C. On cooling further to -24.7 degrees C and then allowing it to warm to +25.0 degrees C, the rotational correlation times of the NaTMIOS were slow to recover to their previous values. For the lipid phase, tau(B)(298) was found to be 65.7 +/- 2.0 ps and the corresponding activation enthalpy, DeltaH, was 32.5 +/- 0.9 kJ mol(-)(1): These values are typical of those expected to be found in the type of fat used to make ice cream. The water phase gave corresponding values of 32.2 +/- 0.5 ps and 24.5 +/- 0.4 kJ mol(-)(1) values, which are those expected for a sucrose concentration of 24%.

  11. Connecting the dots between bacterial biofilms and ice cream

    NASA Astrophysics Data System (ADS)

    Stanley-Wall, Nicola R.; MacPhee, Cait E.

    2015-12-01

    Emerging research is revealing a diverse array of interfacially-active proteins that are involved in varied biological process from foaming horse sweat to bacterial raincoat formation. We describe an interdisciplinary approach to study the molecular and biophysical mechanisms controlling the activity of an unusual bacterial protein called BslA. This protein is needed for biofilm formation and forms a protective layer or raincoat over the bacterial community, but also has a multitude of potential applications in multiphase formulations. Here we document our journey from fundamental research to an examination of the applications for this surface-active protein in ice cream.

  12. Connecting the dots between bacterial biofilms and ice cream.

    PubMed

    Stanley-Wall, Nicola R; MacPhee, Cait E

    2015-12-18

    Emerging research is revealing a diverse array of interfacially-active proteins that are involved in varied biological process from foaming horse sweat to bacterial raincoat formation. We describe an interdisciplinary approach to study the molecular and biophysical mechanisms controlling the activity of an unusual bacterial protein called BslA. This protein is needed for biofilm formation and forms a protective layer or raincoat over the bacterial community, but also has a multitude of potential applications in multiphase formulations. Here we document our journey from fundamental research to an examination of the applications for this surface-active protein in ice cream.

  13. Double blind study of sertaconazole 2% cream vs. clotrimazole 1% cream in treatment of seborrheic dermatitis.

    PubMed

    Goldust, Mohamad; Rezaee, Elham; Rouhani, Shahin

    2013-01-01

    Treatment of seborrheic dermatitis (SD) is an important issue in dermatology. This study was undertaken to compare efficiency of sertaconazole 2% cream vs. clotrimazole 1% cream for the treatment of seborrheic dermatitis. One hundred twenty eight patients suffering from SD were studied. Patients were randomly divided into two groups. Sixty four patients received local sertoconazole 2% cream and in control group 64 patients received clotrimazole 1% cream. They were recommended to use the cream twice a day for 4 weeks. At the beginning of referring and 2 and 4 weeks after first visit, the patients were examined by a dermatologist to assess improvement of clinical symptoms. The mean age of sertaconazole and clotrimazole group patients was 34.78+/-13.54 and 38.68+/-11.88, respectively. The highest level of satisfaction (87.6%) was observed 28 days after sertaconazole administration and in clotrimazole group it was 50%. Relapse of the disease one month after stopping treatment was not observed in groups treated with sertaconazole 2% cream and clotrimazole 1% cream. This study suggests that sertaconazole 2% cream is an effective and well-tolerated treatment for moderate to severe facial seborrheic dermatitis.

  14. Predicting Activity Energy Expenditure Using the Actical[R] Activity Monitor

    ERIC Educational Resources Information Center

    Heil, Daniel P.

    2006-01-01

    This study developed algorithms for predicting activity energy expenditure (AEE) in children (n = 24) and adults (n = 24) from the Actical[R] activity monitor. Each participant performed 10 activities (supine resting, three sitting, three house cleaning, and three locomotion) while wearing monitors on the ankle, hip, and wrist; AEE was computed…

  15. Fabric-based integrated energy devices for wearable activity monitors.

    PubMed

    Jung, Sungmook; Lee, Jongsu; Hyeon, Taeghwan; Lee, Minbaek; Kim, Dae-Hyeong

    2014-09-01

    A wearable fabric-based integrated power-supply system that generates energy triboelectrically using human activity and stores the generated energy in an integrated supercapacitor is developed. This system can be utilized as either a self-powered activity monitor or as a power supply for external wearable sensors. These demonstrations give new insights for the research of wearable electronics.

  16. Characterization of particles in cream cheese.

    PubMed

    Sainani, M R; Vyas, H K; Tong, P S

    2004-09-01

    Cream cheese is used as a spread and as an ingredient in many food applications. A gritty or grainy mouthfeel is an undesirable textural defect that occurs in cream cheese. However, the factors that cause the textural defect are not well understood. The objectives of this study were to isolate and characterize particles from cream cheese and to study the effect of particles on cheese texture. Particles were isolated by washing cream cheese with water first at 25 degrees C and then at 50 degrees C repeatedly 4 to 5 times. The size of these particles was determined using a particle size analyzer. The particles as well as the original cheeses were analyzed for moisture, fat, protein, ash, and lactose. The particle size ranged of 0.04 to 850 microm. It was found that isolated particles were significantly higher in protein content as compared with the whole cheese. To study the effect on the cheese texture, particles were added at 5, 15, and 25% (wt/wt) levels to smooth cream cheese, and a sensory ranking test was done on the samples. Isolated particles were further separated into 2 size classes of 2.5 to 150 microm and > or =150 microm. These particles were then mixed with smooth cream cheese at 16 and 29% (wt/wt), and a sensory test was conducted on these samples. Smooth cream cheese with only 5% (wt/wt) added particles was perceived as significantly grittier than the control sample. This experiment also revealed that the perceived grittiness increased with increase in amount and size of particles.

  17. Local anesthetic cream prepared from lidocaine-tetracaine eutectic mixture.

    PubMed

    Ohzeki, Keiichi; Kitahara, Masaki; Suzuki, Noriko; Taguchi, Kyoji; Yamazaki, Yuki; Akiyama, Shinji; Takahashi, Kentaro; Kanzaki, Yasushi

    2008-04-01

    Local anesthetic creams for the clinical treatment of conditions such as postherpetic neuralgia were prepared as an in-house formulation from the eutectic mixture of lidocaine-tetracaine (LT cream) using two eutectic mixtures of local anesthetic (EMLA) type bases. The LT formulation was compared with a lidocaine-prilocaine (LP cream) eutectic mixture formulated using the same base as EMLA. The chemical stability of lidocaine was examined in advance and was found to be stable for more than 3 months either in LT cream or in LP cream. The release rate of lidocaine from the formulated creams was examined using a cellulose ester membrane. The release rate of lidocaine from LT cream was similar to that from LP cream. The release rate of tetracaine was slightly slower than that of lidocaine in LT cream reflecting the larger molecular size of tetracaine. The penetration rate was examined in vitro using a Yucatan micropig skin. The penetration rate of lidocaine was similar between LT and LP creams. Infiltration anesthesia action examined in guinea pigs indicated that the difference between the two creams was statistically insignificant. The present study suggests the equivalence of the LT and LP creams as a local anesthetic and the potential of LT cream for clinical use either in the easy formulation or in the low-cost formulation.

  18. [Preparation of water in oil type cream with high content of water containing Kochia scoparia fruit and Cnidium monnieri fruit].

    PubMed

    Kohri, Naonori; Yamashita, Miki; Kanazawa, Tsutomu; Kodera, Hajime

    2011-01-01

    Kikisui is a herbal lotion containing Kochia scoparia Fruit and Cnidium monnieri Fruit that is clinically used as an antipruritic for itchy dry skin. However, this formulation is unsuitable for inducing a prolonged effect. Here, we attempted to change the formulation from a lotion to a cream. The cream we chose was a water-in-oil (W/O) type emulsion for enhancing skin compatibility. In addition, the high water content imparts a sensation of coolness. However, it is difficult to prepare a stable W/O type cream with high water content using a mechanical mixing method. Instead, we prepared the W/O type emulsion using liquid crystals. Water containing cocamidopropyl betaine was added to a dispersed phase comprising an oil phase of oleic acid and liquid paraffin that was constantly stirred. Addition of an aqueous solution containing Kochia scoparia Fruit and Cnidium monnieri Fruit decreased the stability of the cream. However, addition of glycerin as a humectant, and ethyl p-hydroxybenzoate/n-butyl p-hydroxybenzoate as preservatives enhanced the stability of the cream. The stability of the emulsion was correlated with the apparent viscosity of the cream. The final W/O type cream had a water content of 83% and was stable for more than 6 months at 4°C. Furthermore, ostol, which is one of the main biologically active herbal compounds, was also stable for more than 6 months.

  19. Chloroxylenol and zinc oxide containing cream (Nels cream) vs. 5% benzoyl peroxide cream in the treatment of acne vulgaris. A double-blind, randomized, controlled trial.

    PubMed

    Papageorgiou, P P; Chu, A C

    2000-01-01

    Forty-one subjects completed a double-blind controlled randomized study comparing the following: (i) Nels cream (containing chloroxylenol and zinc oxide); (ii) 5% benzoyl peroxide cream; and (iii) the vehicle of the Nels cream. Patients applied the medications twice daily for 8 weeks. At the end of the test period there was no significant difference in the reduction of inflammatory and noninflammatory lesion counts achieved by Nels cream and benzoyl peroxide. Both creams proved superior to the vehicle. Efficacy grading by subjects and investigators showed no significant difference between Nels cream and benzoyl peroxide. However, side-effects such as peeling and dryness caused by the treatment were significantly less in the Nels cream group.

  20. An overview of existing raptor contaminant monitoring activities in Europe.

    PubMed

    Gómez-Ramírez, P; Shore, R F; van den Brink, N W; van Hattum, B; Bustnes, J O; Duke, G; Fritsch, C; García-Fernández, A J; Helander, B O; Jaspers, V; Krone, O; Martínez-López, E; Mateo, R; Movalli, P; Sonne, C

    2014-06-01

    Biomonitoring using raptors as sentinels can provide early warning of the potential impacts of contaminants on humans and the environment and also a means of tracking the success of associated mitigation measures. Examples include detection of heavy metal-induced immune system impairment, PCB-induced altered reproductive impacts, and toxicity associated with lead in shot game. Authorisation of such releases and implementation of mitigation is now increasingly delivered through EU-wide directives but there is little established pan-European monitoring to quantify outcomes. We investigated the potential for EU-wide coordinated contaminant monitoring using raptors as sentinels. We did this using a questionnaire to ascertain the current scale of national activity across 44 European countries. According to this survey, there have been 52 different contaminant monitoring schemes with raptors over the last 50years. There were active schemes in 15 (predominantly western European) countries and 23 schemes have been running for >20years; most monitoring was conducted for >5years. Legacy persistent organic compounds (specifically organochlorine insecticides and PCBs), and metals/metalloids were monitored in most of the 15 countries. Fungicides, flame retardants and anticoagulant rodenticides were also relatively frequently monitored (each in at least 6 countries). Common buzzard (Buteo buteo), common kestrel (Falco tinnunculus), golden eagle (Aquila chrysaetos), white-tailed sea eagle (Haliaeetus albicilla), peregrine falcon (Falco peregrinus), tawny owl (Strix aluco) and barn owl (Tyto alba) were most commonly monitored (each in 6-10 countries). Feathers and eggs were most widely analysed although many schemes also analysed body tissues. Our study reveals an existing capability across multiple European countries for contaminant monitoring using raptors. However, coordination between existing schemes and expansion of monitoring into Eastern Europe is needed. This would enable

  1. Active Sites Environmental Monitoring Program: Mid-FY 1991 report

    SciTech Connect

    Ashwood, T.L.; Wickliff, D.S.; Morrissey, C.M.

    1991-10-01

    This report summarizes the activities of the Active Sites Environmental Monitoring Program (ASEMP) from October 1990 through March 1991. The ASEMP was established in 1989 by Solid Waste Operations and the Environmental Sciences Division to provide early detection and performance monitoring at active low-level radioactive waste (LLW) disposal sites in Solid Waste Storage Area (SWSA) 6 and transuranic (TRU) waste storage sites in SWSA 5 as required by chapters II and III of US Department of Energy Order 5820.2A. Monitoring results continue to demonstrate the no LLW is being leached from the storage vaults on the tumulus pads. Loading of vaults on Tumulus II began during this reporting period and 115 vaults had been loaded by the end of March 1991.

  2. Ice cream structural elements that affect melting rate and hardness.

    PubMed

    Muse, M R; Hartel, R W

    2004-01-01

    Statistical models were developed to reveal which structural elements of ice cream affect melting rate and hardness. Ice creams were frozen in a batch freezer with three types of sweetener, three levels of the emulsifier polysorbate 80, and two different draw temperatures to produce ice creams with a range of microstructures. Ice cream mixes were analyzed for viscosity, and finished ice creams were analyzed for air cell and ice crystal size, overrun, and fat destabilization. The ice phase volume of each ice cream were calculated based on the freezing point of the mix. Melting rate and hardness of each hardened ice cream was measured and correlated with the structural attributes by using analysis of variance and multiple linear regression. Fat destabilization, ice crystal size, and the consistency coefficient of the mix were found to affect the melting rate of ice cream, whereas hardness was influenced by ice phase volume, ice crystal size, overrun, fat destabilization, and the rheological properties of the mix.

  3. Enjoying Homemade Ice Cream without the Risk of Salmonella Infection

    MedlinePlus

    ... Contaminants Buy, Store & Serve Safe Food Enjoying Homemade Ice Cream without the Risk of Salmonella Infection Share Tweet ... it Email Print August 2004 Every year homemade ice cream causes several outbreaks of Salmonella infection with up ...

  4. Skin Cancer Cream Linked to 5 Dog Deaths:

    MedlinePlus

    ... medlineplus.gov/news/fullstory_163145.html Skin Cancer Cream Linked to 5 Dog Deaths: FDA Even ingesting ... have died from exposure to a skin cancer cream prescribed for people, according to the U.S. Food ...

  5. Treatment of seborrheic dermatitis, comparison of sertaconazole 2% cream versus ketoconazole 2% cream.

    PubMed

    Lotti, Torello; Goldust, Mohamad; Rezaee, Elham

    2013-05-06

    Objective: There are controversies in the treatment of seborrheic dermatitis. The aim of this study was to compare the efficacy of sertaconazole 2% cream as against ketoconazole 2% cream in the treatment of seborrheic dermatitis. Methods: A total of 132 patients, who had been diagnosed of seborrheic dermatitis were studied. The first group received sertaconazole 2% cream (group A), and the other received ketoconazole 2% cream (group B). At the beginning of referring and also 2 and 4 weeks after first visit, the patients were examined by a dermatologist to control improvement of clinical symptoms and drug side effects. Results: The mean age of sertaconazole and ketoconazole group was 30.18 ± 12.36 and 34.68 ± 10.16, respectively. Patients with moderate Scoring Index (SI) had the most frequency (76.6%) at pretreatment stage with ketoconazole 2% cream. This is when patients with mild SI had the highest frequency (53.3%) at posttreatment stage. In patients who received the sertaconazole 2% cream, the highest frequency was observed in 80% of cases with moderate SI at pretreatment stage, while patients with slight SI had the highest frequency (83.3%) at posttreatment stage. Conclusion: Sertaconazole 2% cream may be an excellent alternative therapeutic modality for treating seborrheic dermatitis.

  6. Treatment of seborrheic dermatitis: the efficiency of sertaconazole 2% cream vs. tacrolimus 0.03% cream.

    PubMed

    Goldust, Mohamad; Rezaee, Elham; Raghifar, Ramin; Hemayat, Sevil

    2013-01-01

    The treatment of seborrheic dermatitis (SD) includes topical antifungal agents to eradicate Malassezia spp. corticosteroids to treat the inflammatory component of the disease, and keratolytics to remove scale and crust. The aim of this study was to compare the efficiency of sertaconazole 2% cream and tacrolimus 0.03% cream in the treatment of seborrheic dermatitis. In this clinical trial study, sixty patients suffering from SD were studied. Thirty patients received local sertaconazole 2% cream with a recommendation to use the cream twice a day for 4 weeks. In the control group, thirty patients received tacrolimus 0.03% cream twice a day for four weeks. At the time of referral, and 2 and 4 weeks after first visit, the patients were examined by a dermatologist to check the improvement of clinical symptoms. The mean ages of the sertaconazole and tacrolimus groups were 30.98 +/- 12.24 and 34.67 +/- 10.82, respectively. The highest level of satisfaction (90%) was observed 28 days after sertaconazole use. Only 83.3% satisfaction was noted in the tacrolimus group. The relationship between patient satisfaction and sertaconazole 2% cream receive in 28th day was significant (P = 0.006). Sertaconazole 2% cream may be an excellent alternative therapeutic modality for treating seborrheic dermatitis.

  7. 21 CFR 135.115 - Goat's milk ice cream.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Goat's milk ice cream. 135.115 Section 135.115... Goat's milk ice cream. (a) Description. Goat's milk ice cream is the food prepared in the same manner prescribed in § 135.110 for ice cream, and complies with all the provisions of § 135.110, except that...

  8. Potential of native Thai aromatic plant extracts in antiwrinkle body creams.

    PubMed

    Leelapornpisid, Pimporn; Wickett, R Randall; Chansakaow, Sunee; Wongwattananukul, Nitima

    2015-01-01

    Antioxidant activities of 10 essential oils and 10 absolutes extracted from Thai aromatic plants were evaluated and compared to thyme oil, trolox, quercetin, and kaempferol by two independent assays: the 2, 2-diphenyl-1-1-picrylhydrazyl (DPPH*) radical scavenging assay and the thiobarbituric acid reactive species (TBARS) assay for lipid peroxidation. We found that four essential oils including ginger oil (Zingiber officinale Roscoe), Wan-sao-long leaf oil (Amomum uliginosum Koen), lemongrass oil (Cymbopogon citratus), holy basil oil (Ocimum sanctum L.), and the absolute of dwarf ylang-ylang [Cananga odorata Hook. f. & Thomson var. fruticosa (Craib) J. Sinclair] exhibited high antioxidant activity in both DPPH and TBARS assays and possessed satisfactory fragrance properties. These were then combined into an essential oil blend (EOB) and retested for antioxidant activity. The EOB also exhibited high antioxidant activity in the above assays. It was then incorporated into a stable cream base as EOB body cream. The EOB body cream was found to be best able under storage in stress conditions and presented significantly higher antioxidant activity than its' cream base both before and after stability testing. The effect of EOB body cream on skin surface topography was evaluated in 29 healthy volunteers using the Skin Visiometer (SV 600 FW, CK Electronic GmbH, Germany). Three parameters, Ra, Rz (roughness), and surface, were analyzed. After 4 weeks of application, the EOB body cream showed significant reductions in surface and Rz compared with before treatment (p < 0.05, paired t-test), and with untreated and placebo treatment (p < 0.05, Duncan test). These results indicate that the essential oils and absolutes from Thai plants may serve as potential sources of natural antioxidants for spa and cosmetic products designed to prevent or treat signs of skin aging.

  9. EarthScope Content Module for IRIS Active Earth Monitor

    NASA Astrophysics Data System (ADS)

    McQuillan, P. J.; Welti, R.; Johnson, J. A.; Shiffman, C. R.; Olds, S. E.

    2012-12-01

    The Active Earth Monitor (AEM) is an interactive computer-based display for university lobbies, museums, visitor centers, schools and libraries. AEM runs in a standard Internet web browser in full screen mode. The display consists of a customizable set of content pages about plate tectonics, earthquakes, volcanoes and tsunamis. Low-cost and simple-to-implement, the Active Earth Monitor provides a way to engage audiences with earth science information without spending resources on a large exhibit. The EarthScope Active Earth Monitor content set highlights the connections between the landscape and the research and monitoring being conducted by EarthScope in partnership with regional monitoring networks. Modules consist of chapters that focus on What is EarthScope?, EarthScope Observatories, and EarthScope Research Results. Content topics are easily explored using a web page button type navigation interface via a touch screen or mouse. A formative evaluation of general public users informed the interface design. Chapters in the modules start with a general overview and proceed to detailed specifics. Each chapter utilizes at least one set of live or near real-time research data (often more than one). This exposes the general public to active ongoing research that is engaging, relevant to the individual user, and explained in easy to understand terms. All live content is updated each time a user accesses the individual page displaying the live data. Leading questions are presented allowing the user to examine the content before accessing the answer via pop-up box. Diagrams and charts of research data have explanatory keys that allow users to self explore all content. Content pages can be created and inserted in the Active Earth Monitor by utilizing the simple HTML/CSS coding.;

  10. Influence of Activity Monitor Location and Bout Duration on Free-Living Physical Activity

    ERIC Educational Resources Information Center

    Heil, Daniel P.; Bennett, Gary G.; Bond, Kathleen S.; Webster, Michael D.; Wolin, Kathleen Y.

    2009-01-01

    The purpose of this study was to evaluate the influence of the location (ankle, hip, wrist) where an activity monitor (AM) is worn and of the minimum bout duration (BD) on physical activity (PA) variables during free-living monitoring. Study 1 participants wore AMs at three locations for 1 day while wearing the Intelligent Device for Energy…

  11. 21 CFR 878.4470 - Surgeon's gloving cream.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Surgeon's gloving cream. 878.4470 Section 878.4470...) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4470 Surgeon's gloving cream. (a) Identification. Surgeon's gloving cream is an ointment intended to be used to lubricate the...

  12. 7 CFR 58.649 - Physical requirements for ice cream.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .... The body shall be firm, have substance and readily melt to a creamy consistency when exposed to room... 7 Agriculture 3 2011-01-01 2011-01-01 false Physical requirements for ice cream. 58.649 Section 58... requirements for ice cream. (a) Flavor. The flavor of the finished ice cream shall be pleasing and...

  13. 7 CFR 58.649 - Physical requirements for ice cream.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... The body shall be firm, have substance and readily melt to a creamy consistency when exposed to room... 7 Agriculture 3 2013-01-01 2013-01-01 false Physical requirements for ice cream. 58.649 Section 58... requirements for ice cream. (a) Flavor. The flavor of the finished ice cream shall be pleasing and...

  14. 7 CFR 58.649 - Physical requirements for ice cream.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    .... The body shall be firm, have substance and readily melt to a creamy consistency when exposed to room... 7 Agriculture 3 2014-01-01 2014-01-01 false Physical requirements for ice cream. 58.649 Section 58... requirements for ice cream. (a) Flavor. The flavor of the finished ice cream shall be pleasing and...

  15. 7 CFR 58.649 - Physical requirements for ice cream.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... The body shall be firm, have substance and readily melt to a creamy consistency when exposed to room... 7 Agriculture 3 2012-01-01 2012-01-01 false Physical requirements for ice cream. 58.649 Section 58... requirements for ice cream. (a) Flavor. The flavor of the finished ice cream shall be pleasing and...

  16. 21 CFR 135.115 - Goat's milk ice cream.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... and hydrolyzed milk proteins may not be used; and paragraphs (f)(1) and (g) of § 135.110 shall not... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Goat's milk ice cream. 135.115 Section 135.115... Goat's milk ice cream. (a) Description. Goat's milk ice cream is the food prepared in the same...

  17. 21 CFR 135.115 - Goat's milk ice cream.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... and hydrolyzed milk proteins may not be used; and paragraphs (f)(1) and (g) of § 135.110 shall not... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Goat's milk ice cream. 135.115 Section 135.115... Goat's milk ice cream. (a) Description. Goat's milk ice cream is the food prepared in the same...

  18. 21 CFR 135.115 - Goat's milk ice cream.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... and hydrolyzed milk proteins may not be used; and paragraphs (f)(1) and (g) of § 135.110 shall not... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Goat's milk ice cream. 135.115 Section 135.115... Goat's milk ice cream. (a) Description. Goat's milk ice cream is the food prepared in the same...

  19. 21 CFR 135.115 - Goat's milk ice cream.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... and hydrolyzed milk proteins may not be used; and paragraphs (f)(1) and (g) of § 135.110 shall not... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Goat's milk ice cream. 135.115 Section 135.115... Goat's milk ice cream. (a) Description. Goat's milk ice cream is the food prepared in the same...

  20. Melasma Associated with Topical Estrogen Cream

    PubMed Central

    Schiechert, Rachel A.; Zaiac, Martin N.

    2017-01-01

    A 47-year-old woman presented with hyperpigmented patches on her upper extremities. The patient had begun using a topical estrogen cream in the affected areas prior to noticing the hyperpigmentation. A diagnosis of melasma secondary to topical estrogen cream was made. While systemic hormones are a well-documented trigger for the development of melasma, this case represents the first report of melasma associated with topical estrogens. Topical estrogens are frequently prescribed to postmenopausal women for skin rejuvenation. Melasma should be discussed as a potential side effect of systemic as well as topical estrogen preparations. PMID:28367263

  1. Vaniqa--eflornithine 13.9% cream.

    PubMed

    Shapiro, J; Lui, H

    2001-04-01

    Eflornithine HCl 13.9% cream is the first topical prescription treatment to be approved by the US FDA for the reduction of unwanted facial hair in women. It irreversibly inhibits ornithine decarboxylase (ODC), an enzyme that catalyzes the rate-limiting step for follicular polyamine synthesis, which is necessary for hair growth. In clinical trials eflornithine cream slowed the growth of unwanted facial hair in up to 60% of women. Improvement occurs gradually over a period of 4-8 weeks or longer. Most reported adverse reactions consisted of minor skin irritation.

  2. Reward sensitivity predicts ice cream-related attentional bias assessed by inattentional blindness.

    PubMed

    Li, Xiaoming; Tao, Qian; Fang, Ya; Cheng, Chen; Hao, Yangyang; Qi, Jianjun; Li, Yu; Zhang, Wei; Wang, Ying; Zhang, Xiaochu

    2015-06-01

    The cognitive mechanism underlying the association between individual differences in reward sensitivity and food craving is unknown. The present study explored the mechanism by examining the role of reward sensitivity in attentional bias toward ice cream cues. Forty-nine college students who displayed high level of ice cream craving (HICs) and 46 who displayed low level of ice cream craving (LICs) performed an inattentional blindness (IB) task which was used to assess attentional bias for ice cream. In addition, reward sensitivity and coping style were assessed by the Behavior Inhibition System/Behavior Activation System Scales and Simplified Coping Style Questionnaire. Results showed significant higher identification rate of the critical stimulus in the HICs than LICs, suggesting greater attentional bias for ice cream in the HICs. It was indicated that attentional bias for food cues persisted even under inattentional condition. Furthermore, a significant correlation was found between the attentional bias and reward sensitivity after controlling for coping style, and reward sensitivity predicted attentional bias for food cues. The mediation analyses showed that attentional bias mediated the relationship between reward sensitivity and food craving. Those findings suggest that the association between individual differences in reward sensitivity and food craving may be attributed to attentional bias for food-related cues.

  3. Accretion disc time lag distributions: applying CREAM to simulated AGN light curves

    NASA Astrophysics Data System (ADS)

    Starkey, D. A.; Horne, Keith; Villforth, C.

    2016-02-01

    Active galactic nuclei (AGN) vary in their brightness across all wavelengths. Moreover, longer wavelength ultraviolet-optical continuum light curves appear to be delayed with respect to shorter wavelength light curves. A simple way to model these delays is by assuming thermal reprocessing of a variable point source (a lamp post) by a blackbody accretion disc. We introduce a new method, CREAM (Continuum REprocessed AGN Markov Chain Monte Carlo), that models continuum variations using this lamp post model. The disc light curves lag the lamp post emission with a time delay distribution sensitive to the disc temperature-radius profile and inclination. We test CREAM's ability to recover both inclination and product of black hole mass and accretion rate {Mdot{M}}, and show that the code is also able to infer the shape of the driving light curve. CREAM is applied to synthetic light curves expected from 1000 s exposures of a 17th magnitude AGN with a 2-m telescope in Sloan g and i bands with Signal-to-Noise Ratio (SNR) of 500-900 depending on the filter and lunar phase. We also test CREAM on poorer quality g and i light curves with SNR = 100. We find in the high-SNR case that CREAM can recover the accretion disc inclination to within an uncertainty of 5° and an {Mdot{M}} to within 0.04 dex.

  4. 21 CFR 884.2730 - Home uterine activity monitor.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Home uterine activity monitor. 884.2730 Section 884.2730 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... the clinic. The HUAM system comprises a tocotransducer, an at-home recorder, a modem, and a...

  5. 21 CFR 884.2730 - Home uterine activity monitor.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Home uterine activity monitor. 884.2730 Section 884.2730 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... the clinic. The HUAM system comprises a tocotransducer, an at-home recorder, a modem, and a...

  6. [The usefulness of protective creams on fragile and aged skin].

    PubMed

    Rueda López, Justo; Guerrero Palmero, Alberto; Muñoz Bueno, Ana Maria; Esquius i Carbonell, Jacint; Rosell Moreno, Carmen

    2005-06-01

    The ADDERMIS protective cream has these properties: it prevents skin maceration, exercises a regenerative effect, has bacteriostatic and bactericide activity, possesses a noted anti-inflammatory effect and reduces the risk of mycotic infections. Its application is indicated for use in cases of: skin lesions, such as bed sores or leg ulcers, which require the use of a barrier product; dermatitis lesions in zones of skin folds or due to diaper use; to prevent friction zones; fragile skin; peeling, zones where cracks in the skin appear...and to use for cases of incontinence when diapers are required.

  7. 78 FR 50420 - Determination That LIDEX (fluocinonide) Cream and LIDEX-E (fluocinonide) Cream and Nine Other...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-19

    ... HUMAN SERVICES Food and Drug Administration Determination That LIDEX (fluocinonide) Cream and LIDEX-E (fluocinonide) Cream and Nine Other Drug Products Were Not Withdrawn From Sale for Reasons of Safety or... NDA 016908 LIDEX (fluocinonide) Cream; Topical, Medicis Pharmaceutical Corp., 7720 0.05%,....

  8. ZipperCream-CG and WhiteAcre-DG: Two Newly-released, Cream-type Southernpea Cultivars

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Efforts to incorporate genes conditioning a persistent green seed phenotype into Zipper Cream and White Acre type backgrounds were completed with the official release of the new southernpea cultivars ZipperCream-CG and WhiteAcre-DG on 29 January 2008. ZipperCream-CG is a high yielding, large-seeded...

  9. ‘ZipperCream-GC’, a Large-seeded, Cream-type Southernpea with a Green Cotyledon Phenotype

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The USDA has released a high yielding, large-seeded, cream-type southernpea cultivar with a green cotyledon phenotype. The new cultivar, named ‘ZipperCream-GC’, can be harvested at the dry-pod stage of maturity without loss of the pea’s fresh green color. ‘ZipperCream-GC’ was developed as a replac...

  10. Topical treatment of actinic keratoses with potassium dobesilate 5% cream. A preliminary open-label study

    PubMed Central

    2011-01-01

    Background Fibroblast growth factor (FGF) is involved in skin tumorigenesis: it promotes cell viability, induces angiogenesis and stimulates invasiveness. Dobesilate is a drug that blocks the activity of FGF. The primary objective was to evaluate the efficacy and tolerability of potassium dobesilate 5% cream in the treatment of actinic keratoses. Methods Potassium dobesilate 5% cream was applied twice daily for 16 weeks to actinic keratosis lesions in 30 patients. The lesions were evaluated clinically at an initial baseline visit, at intermediate visits, and at 16 weeks of treatment. Results The use of potassium dobesilate 5% cream for 16 weeks induced complete regression in 70% of evaluated actinic keratoses, corresponding to grade I, II and III clinical variants, and a partial response (at least 75% reduction of lesions) in 20% of the cases. Conclusion Our preliminary trial shows that potassium dobesilate exerts anti-tumorigenic effects and may play a useful role in the chemoprevention of skin cancers. PMID:21463984

  11. Monitoring cell concentration and activity by multiple excitation fluorometry.

    PubMed

    Li, J K; Asali, E C; Humphrey, A E; Horvath, J J

    1991-01-01

    Four key cellular metabolic fluorophores--tryptophan, pyridoxine, NAD(P)H, and riboflavin--were monitored on-line by a multiple excitation fluorometric system (MEFS) and a modified SLM 8000C scanning spectrofluorometer in three model yeast fermentation systems--bakers' yeast growing on glucose, Candida utilis growing on ethanol, and Saccharomyces cerevisiae RTY110/pRB58 growing on glucose. The measured fluorescence signals were compared with cell concentration, protein concentration, and cellular activity. The results indicate that the behavior and fluorescence intensity of various fluorophores differ in the various fermentation systems. Tryptophan fluorescence is the best signal for the monitoring of cell concentration in bakers' yeast and C. utilis fermentations. Pyridoxine fluoresce is the best signal for the monitoring of cell concentration in the S. cerevisiae RTY110/pRB58 fermentation. In bakers' yeast fermentations the pyridoxine fluorescence signal can be used to monitor cellular activity. The NAD(P)H fluorescence signal is a good indicator of cellular activity in the C. utilis fermentation. For this fermentation NAD(P)H fluorescence can be used to control ethanol feeding in a fed-batch process.

  12. [Evaluation of Cepan Cream after 15 years of treatment of burn scars].

    PubMed

    Stozkowska, Wiesława

    2002-01-01

    Cepan Cream is used for the topical treatment of scars and keloids resulting from burns, post-operative scars, and contractures. Cepan Cream makes scars more elastic, softer and paler. Plant extracts, heparin and allantoin in Cepan act on the biochemical processes in the developing connective tissue, preventing the formation of hyperplastic scars. These active ingredients enhance swelling, softening and loosening of connective tissue. It exerts softening and smoothing action on indurated and hyperplastic scar tissue, improving collagen structure. It promotes tissue regeneration and reduces exuberant granulation. Cepan is well tolerated.

  13. Limited activity monitoring in toddlers with autism spectrum disorder.

    PubMed

    Shic, Frederick; Bradshaw, Jessica; Klin, Ami; Scassellati, Brian; Chawarska, Katarzyna

    2011-03-22

    This study used eye-tracking to examine how 20-month-old toddlers with autism spectrum disorder (ASD) (n=28), typical development (TD) (n=34), and non-autistic developmental delays (DD) (n=16) monitored the activities occurring in a context of an adult-child play interaction. Toddlers with ASD, in comparison to control groups, showed less attention to the activities of others and focused more on background objects (e.g., toys). In addition, while all groups spent the same time overall looking at people, toddlers with ASD looked less at people's heads and more at their bodies. In ASD, these patterns were associated with cognitive deficits and greater autism severity. These results suggest that the monitoring of the social activities of others is disrupted early in the developmental progression of autism, limiting future avenues for observational learning.

  14. Monitoring and evaluating school nutrition and physical activity policies.

    PubMed

    Taylor, Jennifer P; McKenna, Mary L; Butler, Gregory P

    2010-01-01

    Given the increase in the number of Canadian jurisdictions with school nutrition and/or physical activity policies, there is a need to assess the effectiveness of such policies. The objectives of this paper are to 1) provide an overview of key issues in monitoring and evaluating school nutrition and physical activity policies in Canada and 2) identify areas for further research needed to strengthen the evidence base and inform the development of effective approaches to monitoring and evaluation. Evaluation indicators, data sources and existing tools for evaluating nutrition and physical activity are reviewed. This paper has underscored the importance of identifying common indicators and approaches, using a comprehensive approach based on the WHO framework and ensuring that research capacity and funding is in place to facilitate high-quality evaluation efforts in the future.

  15. 21 CFR 524.2350 - Tolnaftate cream.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Tolnaftate cream. 524.2350 Section 524.2350 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL...) Conditions of use. (1) The drug is indicated for treatment of ringworm lesions due to Microsporum canis...

  16. 21 CFR 524.2350 - Tolnaftate cream.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 6 2012-04-01 2012-04-01 false Tolnaftate cream. 524.2350 Section 524.2350 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL...) Conditions of use. (1) The drug is indicated for treatment of ringworm lesions due to Microsporum canis...

  17. 21 CFR 524.2350 - Tolnaftate cream.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 6 2014-04-01 2014-04-01 false Tolnaftate cream. 524.2350 Section 524.2350 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL.... For the treatment of ringworm lesions due to Microsporum canis and Microsporum gypseum....

  18. 21 CFR 524.2350 - Tolnaftate cream.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Tolnaftate cream. 524.2350 Section 524.2350 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL...) Conditions of use. (1) The drug is indicated for treatment of ringworm lesions due to Microsporum canis...

  19. 21 CFR 133.133 - Cream cheese.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... enzymes specified in paragraph (b)(2) of this section is added to coagulate the dairy ingredients. The..., nonfat milk, or cream, as defined in § 133.3, used alone or in combination. (2) Clotting enzymes. Rennet and/or other clotting enzymes of animal, plant, or microbial origin. (3) Other optional...

  20. 21 CFR 133.133 - Cream cheese.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... enzymes specified in paragraph (b)(2) of this section is added to coagulate the dairy ingredients. The..., nonfat milk, or cream, as defined in § 133.3, used alone or in combination. (2) Clotting enzymes. Rennet and/or other clotting enzymes of animal, plant, or microbial origin. (3) Other optional...

  1. 21 CFR 133.133 - Cream cheese.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... enzymes specified in paragraph (b)(2) of this section is added to coagulate the dairy ingredients. The..., nonfat milk, or cream, as defined in § 133.3, used alone or in combination. (2) Clotting enzymes. Rennet and/or other clotting enzymes of animal, plant, or microbial origin. (3) Other optional...

  2. 21 CFR 524.520 - Cuprimyxin cream.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Cuprimyxin cream. 524.520 Section 524.520 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS..., dermatophytes (Trichophyton spp., Microsporum spp.) and yeast (Candida albicans) affecting skin, hair,...

  3. Filtrates and Residues: Ice Cream: Delicious Chemistry.

    ERIC Educational Resources Information Center

    Martino, James

    1983-01-01

    An experiment involving preparation of ice cream is conducted after students complete units on solutions, atomic structure, molecular architecture, and bonding. The laboratory gives practical illustration of relation of physical properties to bond type and solution theory developed. Materials needed, procedures used, and questions asked are…

  4. 7 CFR 58.349 - Frozen cream.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Products Bearing Usda Official Identification § 58.349 Frozen cream. The flavor shall be sweet, pleasing and desirable, but may possess the following flavors to a slight degree: Aged, bitter, flat, smothered, storage; and cooked and feed flavors to a definite degree. It shall be free from rancid, oxidized or...

  5. Clinical study of sertaconazole 2% cream vs. hydrocortisone 1% cream in the treatment of seborrheic dermatitis.

    PubMed

    Goldust, Mohamad; Rezaee, Elham; Masoudnia, Sima; Raghifar, Ramin

    2013-01-01

    Seborrheic dermatitis (SD) is an inflammatory skin disorder affecting the scalp, face, and trunk, however, there are controversies surrounding its treatment. The aim of the study is to compare the efficacy of sertaconazole 2% cream with hydrocortisone 1% cream in the treatment of seborrheic dermatitis. In total, 138 patients suffering from seborrheic dermatitis were studied. Sixty-nine patients received local sertoconazole 2% cream and they were recommended to use the cream twice a day and for 4 weeks. To create a control group, 69 patients received hydrocortisone 1% cream twice a day for four weeks. At the time of referral, and at 2 and 4 weeks after their first visit, the patients were examined by a dermatologist to check the improvement of clinical symptoms. The mean age of patients was 36.45 +/- 13.23. The highest level of satisfaction (85.1%) was observed 28 days after sertaconazole consumption: 76.9% was recorded for the hydrocortisone group. No relapse of the disease one month after stopping treatment was observed in either the sertaconazole 2% group or the hydrocortisone 1% group. Sertaconazole 2% cream may be an excellent alternative therapeutic modality for treating seborrheic dermatitis.

  6. Production of functional probiotic, prebiotic, and synbiotic ice creams.

    PubMed

    Di Criscio, T; Fratianni, A; Mignogna, R; Cinquanta, L; Coppola, R; Sorrentino, E; Panfili, G

    2010-10-01

    In this work, 3 types of ice cream were produced: a probiotic ice cream produced by adding potentially probiotic microorganisms such as Lactobacillus casei and Lactobacillus rhamnosus; a prebiotic ice cream produced by adding inulin, a prebiotic substrate; and a synbiotic ice cream produced by adding probiotic microorganisms and inulin in combination. In addition to microbial counts, pH, acidity, and physical and functional properties of the ice creams were evaluated. The experimental ice creams preserved the probiotic bacteria and had counts of viable lactic acid bacteria after frozen storage that met the minimum required to achieve probiotic effects. Moreover, most of the ice creams showed good nutritional and sensory properties, with the best results obtained with Lb. casei and 2.5% inulin.

  7. The value to the anaesthetist of monitoring cerebral activity.

    PubMed

    Langford, R M; Thomsen, C E

    1994-03-01

    The administration rate of general anaesthetic drugs is at present guided by clinical experience, and indirect indicators such as haemodynamic parameters. In the presence of muscle relaxants most of the clinical signs of inadequate anaesthesia are lost and accidental awareness may occur. A number of monitoring modalities, primarily based on analysis of the electroencephalogram (EEG), have been proposed for measurement of the anaesthetic depth. Moreover intraoperative cerebral monitoring may also provide the anaesthetist with early warning of cerebral ischaemia, or information on specific neurological pathways. To facilitate this, it is essential to combine analysis of the spontaneous EEG with recording of evoked potentials, to assess both cortical and subcortical activity/events. None of the reviewed methods, however promising, can alone meet all of the requirements for intraoperative monitoring of cerebral function. We suggest that the future direction should be to integrate several modalities in a single device, to provide valuable new information, upon which to base clinical management decisions.

  8. On-line Monitoring and Active Control for Transformer Noise

    NASA Astrophysics Data System (ADS)

    Liang, Jiabi; Zhao, Tong; Tian, Chun; Wang, Xia; He, Zhenhua; Duan, Lunfeng

    This paper introduces the system for on-line monitoring and active noise control towards the transformer noise based on LabVIEW and the hardware equipment including the hardware and software. For the hardware part, it is mainly focused on the composition and the role of hardware devices, as well as the mounting location in the active noise control experiment. And the software part introduces the software flow chats, the measurement and analysis module for the sound pressure level including A, B, C weighting methods, the 1/n octave spectrum and the power spectrum, active noise control module and noise data access module.

  9. Formulation and Evaluation of Antibacterial Creams and Gels Containing Metal Ions for Topical Application

    PubMed Central

    Chen, Mei X.; Alexander, Kenneth S.

    2016-01-01

    Background. Skin infections occur commonly and often present therapeutic challenges to practitioners due to the growing concerns regarding multidrug-resistant bacterial, viral, and fungal strains. The antimicrobial properties of zinc sulfate and copper sulfate are well known and have been investigated for many years. However, the synergistic activity between these two metal ions as antimicrobial ingredients has not been evaluated in topical formulations. Objective. The aims of the present study were to (1) formulate topical creams and gels containing zinc and copper alone or in combination and (2) evaluate the in vitro antibacterial activity of these metal ions in the formulations. Method. Formulation of the gels and creams was followed by evaluating their organoleptic characteristics, physicochemical properties, and in vitro antibacterial activity against Escherichia coli and Staphylococcus aureus. Results. Zinc sulfate and copper sulfate had a strong synergistic antibacterial activity in the creams and gels. The minimum effective concentration was found to be 3 w/w% for both active ingredients against the two tested microorganisms. Conclusions. This study evaluated and confirmed the synergistic in vitro antibacterial effect of copper sulfate and zinc sulfate in a cream and two gels. PMID:27885352

  10. Active Sites Environmental Monitoring Program: Program plan. Revision 1

    SciTech Connect

    Ashwood, T.L.; Wickliff, D.S.; Morrissey, C.M.

    1992-02-01

    The Active Sites Environmental Monitoring Program (ASEMP), initiated in 1989, provides early detection and performance monitoring of transuranic (TRU) waste and active low-level waste (LLW) facilities at Oak Ridge National Laboratory (ORNL) in accordance with US Department of Energy (DOE) Order 5820.2A. Active LLW facilities in Solid Waste Storage Area (SWSA) 6 include Tumulus I and Tumulus II, the Interim Waste Management Facility (IWMF), LLW silos, high-range wells, asbestos silos, and fissile wells. The tumulus pads and IWMF are aboveground, high-strength concrete pads on which concrete vaults containing metal boxes of LLW are placed; the void space between the boxes and vaults is filled with grout. Eventually, these pads and vaults will be covered by an engineered multilayered cap. All other LLW facilities in SWSA 6 are below ground. In addition, this plan includes monitoring of the Hillcut Disposal Test Facility (HDTF) in SWSA 6, even though this facility was completed prior to the data of the DOE order. In SWSA 5 North, the TRU facilities include below-grade engineered caves, high-range wells, and unlined trenches. All samples from SWSA 6 are screened for alpha and beta activity, counted for gamma-emitting isotopes, and analyzed for tritium. In addition to these analytes, samples from SWSA 5 North are analyzed for specific transuranic elements.

  11. Sentinel-1 Contribution to Monitoring Maritime Activity in the Arctic

    NASA Astrophysics Data System (ADS)

    Santamaria, Carlos; Greidanus, Harm; Fournier, Melanie; Eriksen, Torkild; Vespe, Michele; Alvarez, Marlene; Arguedas, Virginia Fernandez; Delaney, Conor; Argentieri, Pietro

    2016-08-01

    This paper presents results on the use of Sentinel-1 combined with satellite AIS to monitor maritime activity in the Arctic. Such activities are expected to increase, even if not uniformly across the Arctic, as the ice cover in the region retreats due to changes in climate. The objectives of monitoring efforts in the region can vary from country to country, but are generally related to increasing awareness on non- cooperative, small and cruise ships, fisheries, safety at sea, and Search and Rescue. A ship monitoring study has been conducted, involving more than 2,000 Sentinel-1 images acquired during one year in the central Arctic, where the ship densities are high. The main challenges to SAR-based monitoring in this area are described, solutions for some of them are proposed, and analyses of the results are shown. With the high detection thresholds needed to prevent false alarms from sea ice, 16% of the ships detected overall in the Sentinel-1 images have not been correlated to AIS- transmitting ships, and 48% of the AIS-transmitting ships are not correlated to ships detected in the images.

  12. Toward Active Monitoring of Piping Using Ultrasonic Guided Waves

    SciTech Connect

    Park, Joon-Soo; Kim, Young H.; Song, Sung-Jin; Kim, Jae-Hee; Eom, Heung-Seop; Im, Kwang-Hee

    2004-02-26

    Piping in nuclear power plants is exposed to severe environmental conditions so that it is very susceptible to failure caused by the growth of defects. Thus, it is necessary to have thorough inspection of piping in order to detect defects before failure. Unfortunately, however, inspection of piping in nuclear power plants is not easy in practice because of its long length as well as the radioactive environment. To take care of this difficulty, a research endeavor to develop techniques to monitor piping in nuclear power plants continuously and actively using ultrasonic guided wave is currently undertaken. This paper reports initial results of our endeavor including design of an ultrasonic array system for active monitoring of piping.

  13. Energy monitoring system based on human activity in the workplace

    NASA Astrophysics Data System (ADS)

    Mustafa, Nur Hanim; Husain, Mohd Nor; Aziz, Mohamad Zoinol Abidin Abdul; Othman, Mohd Azlishah; Malek, Fareq

    2015-05-01

    Human behaviors always related to day routine activities in a smart house directly give the significant factor to manage energy usage in human life. An Addition that, the factor will contribute to the best efficiency of the system. This paper will focus on the monitoring efficiency based on duration time in office hours around 8am until 5pm which depend on human behavior at working place. Besides that, the correlation coefficient method is used to show the relation between energy consumption and energy saving based on the total hours of time energy spent. In future, the percentages of energy monitoring system usage will be increase to manage energy saving based on human behaviors. This scenario will help to see the human activity in the workplace in order to get the energy saving and support world green environment.

  14. Method for monitoring stack gases for uranium activity

    DOEpatents

    Beverly, Claude R.; Ernstberger, Harold G.

    1988-01-01

    A method for monitoring the stack gases of a purge cascade of a gaseous diffusion plant for uranium activity. A sample stream is taken from the stack gases and contacted with a volume of moisture-laden air for converting trace levels of uranium hexafluoride, if any, in the stack gases into particulate uranyl fluoride. A continuous strip of filter paper from a supply roll is passed through this sampling stream to intercept and gather any uranyl fluoride in the sampling stream. This filter paper is then passed by an alpha scintillation counting device where any radioactivity on the filter paper is sensed so as to provide a continuous monitoring of the gas stream for activity indicative of the uranium content in the stack gases.

  15. Method for monitoring stack gases for uranium activity

    DOEpatents

    Beverly, C.R.; Ernstberger, E.G.

    1985-07-03

    A method for monitoring the stack gases of a purge cascade of gaseous diffusion plant for uranium activity. A sample stream is taken from the stack gases and contacted with a volume of moisture-laden air for converting trace levels of uranium hexafluoride, if any, in the stack gases into particulate uranyl fluoride. A continuous strip of filter paper from a supply roll is passed through this sampling stream to intercept and gather any uranyl fluoride in the sampling stream. This filter paper is then passed by an alpha scintillation counting device where any radioactivity on the filter paper is sensed so as to provide a continuous monitoring of the gas stream for activity indicative of the uranium content in the stack gases. 1 fig.

  16. [Proof of the effectiveness of a clotrimazole cream paste in acne vulgaris].

    PubMed

    Huber, H P; Nook, T

    1986-03-01

    The efficacy of Clotrimazol cream paste containing a penetration enhancer in the treatment of acne vulgaris was objectified by investigating the sebum composition. Following treatment over three and six weeks, the ratio of triglyceride to free fatty acid significantly increased, which indicated an effective reduction of the lipase activity of Propionibacterium acnes within the sebaceous follicle.

  17. Improving the outcome of fractional CO2 laser resurfacing using a probiotic skin cream: Preliminary clinical evaluation.

    PubMed

    Zoccali, Giovanni; Cinque, Benedetta; La Torre, Cristina; Lombardi, Francesca; Palumbo, Paola; Romano, Lucia; Mattei, Antonella; Orsini, Gino; Cifone, Maria Grazia; Giuliani, Maurizio

    2016-11-01

    As known, fractional CO2 resurfacing treatments are more effective than non-ablative ones against aging signs, but post-operative redness and swelling prolong the overall downtime requiring up to steroid administration in order to reduce these local systems. In the last years, an increasing interest has been focused on the possible use of probiotics for treating inflammatory and allergic conditions suggesting that they can exert profound beneficial effects on skin homeostasis. In this work, the Authors report their experience on fractional CO2 laser resurfacing and provide the results of a new post-operative topical treatment with an experimental cream containing probiotic-derived active principles potentially able to modulate the inflammatory reaction associated to laser-treatment. The cream containing DermaACB (CERABEST™) was administered post-operatively to 42 consecutive patients who were treated with fractional CO2 laser. All patients adopted the cream twice a day for 2 weeks. Grades were given according to outcome scale. The efficacy of the cream containing DermaACB was evaluated comparing the rate of post-operative signs vanishing with a control group of 20 patients topically treated with an antibiotic cream and a hyaluronic acid based cream. Results registered with the experimental treatment were good in 22 patients, moderate in 17, and poor in 3 cases. Patients using the study cream took an average time of 14.3 days for erythema resolution and 9.3 days for swelling vanishing. The post-operative administration of the cream containing DermaACB induces a quicker reduction of post-operative erythema and swelling when compared to a standard treatment.

  18. Active Geophysical Monitoring in Oil and Gas Industry

    NASA Astrophysics Data System (ADS)

    Bakulin, A.; Calvert, R.

    2005-12-01

    Effective reservoir management is a Holy Grail of the oil and gas industry. Quest for new technologies is never ending but most often they increase effectiveness and decrease the costs. None of the newcomers proved to be a silver bullet in such a key metric of the industry as average oil recovery factor. This factor is still around 30 %, meaning that 70 % of hydrocarbon reserves are left in the ground in places where we already have expensive infrastructure (platforms, wells) to extract them. Main reason for this inefficiency is our inability to address realistic reservoir complexity. Most of the time we fail to properly characterize our reservoirs before production. As a matter of fact, one of the most important parameters -- permeability -- can not be mapped from remote geophysical methods. Therefore we always start production blind even though reservoir state before production is the simplest one. Once first oil is produced, we greatly complicate the things and quickly become unable to estimate the state and condition of the reservoir (fluid, pressures, faults etc) or oilfield hardware (wells, platforms, pumps) to make a sound next decision in the chain of reservoir management. Our modeling capabilities are such that if we know true state of the things - we can make incredibly accurate predictions and make extremely efficient decisions. Thus the bottleneck is our inability to properly describe the state of the reservoirs in real time. Industry is starting to recognize active monitoring as an answer to this critical issue. We will highlight industry strides in active geophysical monitoring from well to reservoir scale. It is worth noting that when one says ``monitoring" production technologists think of measuring pressures at the wellhead or at the pump, reservoir engineers think of measuring extracted volumes and pressures, while geophysicist may think of change in elastic properties. We prefer to think of monitoring as to measuring those parameters of the

  19. Integrated active sensor system for real time vibration monitoring.

    PubMed

    Liang, Qijie; Yan, Xiaoqin; Liao, Xinqin; Cao, Shiyao; Lu, Shengnan; Zheng, Xin; Zhang, Yue

    2015-11-05

    We report a self-powered, lightweight and cost-effective active sensor system for vibration monitoring with multiplexed operation based on contact electrification between sensor and detected objects. The as-fabricated sensor matrix is capable of monitoring and mapping the vibration state of large amounts of units. The monitoring contents include: on-off state, vibration frequency and vibration amplitude of each unit. The active sensor system delivers a detection range of 0-60 Hz, high accuracy (relative error below 0.42%), long-term stability (10000 cycles). On the time dimension, the sensor can provide the vibration process memory by recording the outputs of the sensor system in an extend period of time. Besides, the developed sensor system can realize detection under contact mode and non-contact mode. Its high performance is not sensitive to the shape or the conductivity of the detected object. With these features, the active sensor system has great potential in automatic control, remote operation, surveillance and security systems.

  20. Integrated active sensor system for real time vibration monitoring

    PubMed Central

    Liang, Qijie; Yan, Xiaoqin; Liao, Xinqin; Cao, Shiyao; Lu, Shengnan; Zheng, Xin; Zhang, Yue

    2015-01-01

    We report a self-powered, lightweight and cost-effective active sensor system for vibration monitoring with multiplexed operation based on contact electrification between sensor and detected objects. The as-fabricated sensor matrix is capable of monitoring and mapping the vibration state of large amounts of units. The monitoring contents include: on-off state, vibration frequency and vibration amplitude of each unit. The active sensor system delivers a detection range of 0–60 Hz, high accuracy (relative error below 0.42%), long-term stability (10000 cycles). On the time dimension, the sensor can provide the vibration process memory by recording the outputs of the sensor system in an extend period of time. Besides, the developed sensor system can realize detection under contact mode and non-contact mode. Its high performance is not sensitive to the shape or the conductivity of the detected object. With these features, the active sensor system has great potential in automatic control, remote operation, surveillance and security systems. PMID:26538293

  1. Human psychophysiological activity monitoring methods using fiber optic sensors

    NASA Astrophysics Data System (ADS)

    Zyczkowski, M.; Uzieblo-Zyczkowska, B.

    2010-10-01

    The paper presents the concept of fiber optic sensor system for human psycho-physical activity detection. A fiber optic sensor that utilizes optical phase interferometry or intensity in modalmetric to monitor a patient's vital signs such as respiration cardiac activity, blood pressure and body's physical movements. The sensor, which is non-invasive, comprises an optical fiber interferometer that includes an optical fiber proximately situated to the patient so that time varying acusto-mechanical signals from the patient are coupled into the optical fiber. The system can be implemented in embodiments ranging form a low cost in-home to a high end product for in hospital use.

  2. Development of technology for manufacture of ragi ice cream.

    PubMed

    Patel, I J; Dharaiya, C N; Pinto, S V

    2015-07-01

    Ragi (Finger millet) improves the nutritional value of ice cream by enhancing the iron and fibre content. Caramel flavoured medium fat ice cream (6 % fat) was prepared by addition of gelatinized malted ragi flour roasted in butter (MRB) @ 8 %, 9 % and 10 % by weight of mix and compared with control (C) i.e. vanilla ice cream containing 10 % fat. The overall acceptability score of product prepared using 9 % MRB was statistically (P > 0.05) at par with the C, hence, it was selected. In the next part of the study, ragi ice cream was prepared using 4 different flavours viz. vanilla, mango, chocolate and caramel. Chocolate flavoured ragi ice cream was adjudged as best, followed by mango, caramel and vanilla ice cream. The iron and fibre content of chocolate flavoured ragi ice cream was found to be 12.8 ppm and 1.36 % respectively. vs. 1.5 ppm and 0.18 % respectively in control (C). Heat shock treatment as well as storage up to 30 days had no adverse effect on the sensory quality of the chocolate flavored ragi ice cream. Incorporation of finger millet in ice cream resulted in reduction in the amount of stabilizer used and effectively functioned as fat replacer in ice cream.

  3. In-vessel activation monitors in JET: Progress in modeling

    SciTech Connect

    Bonheure, Georges; Lengar, I.; Syme, B.; Popovichev, S.; Arnold, Dirk; Laubenstein, Matthias

    2008-10-15

    Activation studies were performed in JET with new in-vessel activation monitors. Though primarily dedicated to R and D in the challenging issue of lost {alpha} diagnostics for ITER, which is being addressed at JET with several techniques, these monitors provide for both neutron and charged particle fluences. A set of samples with different orientation with respect to the magnetic field is transported inside the torus by means of a manipulator arm (in contrast with the conventional JET activation system with pneumatic transport system). In this case, radionuclides with longer half-life were selected and ultralow background gamma-ray measurements were needed. The irradiation was closer to the plasma and this potentially reduces the neutron scattering problem. This approach could also be of interest for ITER, where the calibration methods have yet to be developed. The MCNP neutron transport model for JET was modified to include the activation probe and so provide calculations to help assess the new data. The neutron induced activity on the samples are well reproduced by the calculations.

  4. Advanced Performance Modeling with Combined Passive and Active Monitoring

    SciTech Connect

    Dovrolis, Constantine; Sim, Alex

    2015-04-15

    To improve the efficiency of resource utilization and scheduling of scientific data transfers on high-speed networks, the "Advanced Performance Modeling with combined passive and active monitoring" (APM) project investigates and models a general-purpose, reusable and expandable network performance estimation framework. The predictive estimation model and the framework will be helpful in optimizing the performance and utilization of networks as well as sharing resources with predictable performance for scientific collaborations, especially in data intensive applications. Our prediction model utilizes historical network performance information from various network activity logs as well as live streaming measurements from network peering devices. Historical network performance information is used without putting extra load on the resources by active measurement collection. Performance measurements collected by active probing is used judiciously for improving the accuracy of predictions.

  5. Changes in electrical energy requirements to operate an ice cream freezer as a function of sweeteners and gums

    SciTech Connect

    Smith, D.E.; Bakshi, A.S.; Gay, S.A.

    1985-01-01

    Changes in electrical energy required to operate a continuous freezer were monitored for various ice cream formulae. Ice cream formulae consisted of nine different combinations of sucrose, 36 DE corn syrup, and 42 high fructose corn syrup as well as two ratios of guar gum to locust bean gum. Within the same sweetening system, a mix high in locust bean gum tended to have a lower energy demand than mix with large amounts of guar gum. This was especially pronounced in mixes with 50% 42 high fructose corn syrup and/or 50% 36 DE corn syrup solids.

  6. Design considerations in an active medical product safety monitoring system.

    PubMed

    Gagne, Joshua J; Fireman, Bruce; Ryan, Patrick B; Maclure, Malcolm; Gerhard, Tobias; Toh, Sengwee; Rassen, Jeremy A; Nelson, Jennifer C; Schneeweiss, Sebastian

    2012-01-01

    Active medical product monitoring systems, such as the Sentinel System, will utilize electronic healthcare data captured during routine health care. Safety signals that arise from these data may be spurious because of chance or bias, particularly confounding bias, given the observational nature of the data. Applying appropriate monitoring designs can filter out many false-positive and false-negative associations from the outset. Designs can be classified by whether they produce estimates based on between-person or within-person comparisons. In deciding which approach is more suitable for a given monitoring scenario, stakeholders must consider the characteristics of the monitored product, characteristics of the health outcome of interest (HOI), and characteristics of the potential link between these. Specifically, three factors drive design decisions: (i) strength of within-person and between-person confounding; (ii) whether circumstances exist that may predispose to misclassification of exposure or misclassification of the timing of the HOI; and (iii) whether the exposure of interest is predominantly transient or sustained. Additional design considerations include whether to focus on new users, the availability of appropriate active comparators, the presence of an exposure time trend, and the measure of association of interest. When the key assumptions of self-controlled designs are fulfilled (i.e., lack of within-person, time-varying confounding; abrupt HOI onset; and transient exposure), within-person comparisons are preferred because they inherently avoid confounding by fixed factors. The cohort approach generally is preferred in other situations and particularly when timing of exposure or outcome is uncertain because cohort approaches are less vulnerable to biases resulting from misclassification.

  7. Growth of Creamed TNT on Thermal Cycling

    DTIC Science & Technology

    1978-07-01

    of Electrical Engineers- Eng land Overseas Reports Section, Defence Research lntormation Centre, England Engineering Societies Library, U.S.A. Library, Chemical Abstracts Service, U.S.A. ...MRL-R-720 AR-000-899 Jj AUSl vALIA!- DEPARTMENT OF DEFENCE DEFENCE SCIENCE AND TECHNOLOGY ORGANISATION MATERIALS RESEARCH LABORATORIES MELBOURNE...IPLPRODUCL AND SELL THIS REPORT DEPARTMENT OF DEFENCE MATERIALS RESEARCH LABORATORIES REPORT -M R L --R- 729" GROWTH OF CREAMED TNT ON

  8. Comparative Assessment of the Efficacy and Safety of Sertaconazole (2%) Cream Versus Terbinafine Cream (1%) Versus Luliconazole (1%) Cream In Patients with Dermatophytoses: A Pilot Study

    PubMed Central

    Jerajani, HR; Janaki, C; Kumar, Sharath; Phiske, Meghana

    2013-01-01

    Background: Sertaconazole is a new, broad spectrum, fungicidal and fungistatic imidazole with added antipruritic and anti-inflammatory activity that would provide greater symptomatic relief and hence would be beneficial in improving the quality of life for the patient with dermatophytoses. Aims and Objectives: To compare efficacy and safety of sertaconazole, terbinafine and luliconazole in patients with dermatophytoses. Materials and Methods: 83 patients with tinea corporis and tinea cruris infections were enrolled in this multicentre, randomized, open label parallel study. The initial ‘Treatment Phase’ involved three groups receiving either sertaconazole 2% cream applied topically twice daily for four weeks, terbinafine 1% cream once daily for two weeks, luliconazole 1% cream once daily for two weeks. At the end of treatment phase, there was a ‘Follow-up Phase’ at end of 2 weeks, where the patients were assessed clinically and mycologically for relapse. Results: Of the 83 patients, 62 completed the study, sertaconazole (n = 20), terbinafine (n = 22) and luliconazole (n = 20). The primary efficacy variables including change in pruritus, erythema, vesicle, desquamation and mycological cure were significantly improved in all the three groups, as compared to baseline, in the Treatment and Follow-up phase. Greater proportion of patients in sertaconazole group (85%) showed resolution of pruritus as compared to terbinafine (54.6%); and luliconazole (70%), (P < 0.05 sertaconazole vs terbinafine). There was a greater reduction in mean total composite score (pruritus, erythema, vesicle and desquamation) in sertaconazole group (97.1%) as compared to terbinafine (91.2%) and luliconazole (92.9%). All groups showed equal negative mycological assessment without any relapses. All three study drugs were well tolerated. Only one patient in sertaconazole group withdrew from the study due to suspected allergic contact dermatitis. Conclusion: Sertaconazole was better than

  9. FRET-based optical assay for monitoring riboswitch activation.

    PubMed

    Harbaugh, Svetlana; Kelley-Loughnane, Nancy; Davidson, Molly; Narayanan, Latha; Trott, Sandra; Chushak, Yaroslav G; Stone, Morley O

    2009-05-11

    Riboswitches are regulatory RNAs located in the 5'-untranslated region of mRNA sequences that recognize and bind to small molecules and regulate the expression of downstream genes. Creation of synthetic riboswitches to novel ligands depends on the ability to monitor riboswitch activation in the presence of analyte. In our work, we have coupled a synthetic riboswitch to an optical reporter assay based on fluorescence resonance energy transfer (FRET) between two genetically encoded fluorescent proteins. The theophylline-sensitive riboswitch was placed upstream of the Tobacco Etch Virus (TEV) protease coding sequence. Our FRET construct was composed of eGFP and a nonfluorescent yellow fluorescent protein mutant called REACh (for resonance energy-accepting chromoprotein) connected with a peptide linker containing a TEV protease cleavage site. Addition of theophylline to the E. coli cells activates the riboswitch and initiates the translation of mRNA. Synthesized protease cleaves the linker in the FRET-based fusion protein causing a change in the fluorescence signal. By this method, we observed an 11-fold increase in cellular extract fluorescence in the presence of theophylline. The advantage of using an eGFP-REACh pair is the elimination of acceptor fluorescence. This leads to an improved detection of FRET via better signal-to-noise ratio, allowing us to monitor riboswitch activation in a wide range of analyte concentrations from 0.01 to 2.5 mM.

  10. Monitoring Heparin Therapy with the Activated Partial Thromboplastin Time

    PubMed Central

    Stuart, R. K.; Michel, A.

    1971-01-01

    Difficulties associated with the whole blood clotting time (W.B.C.T.) as a method of monitoring heparin therapy have led to the investigation of the activated partial thromboplastin time (A.P.T.T.) as an alternative. The conclusion is reached that the latter procedure possesses several advantages. Using the method described and a citrate-preserved blood sample collected just prior to the administration of the next serial dose of heparin, the suggested therapeutic duration of the A.P.T.T. is 70 seconds or twice the mean control value. A practical range for this method is 60 to 70 seconds. PMID:5557913

  11. Monitoring rice farming activities in the Mekong Delta region

    NASA Astrophysics Data System (ADS)

    Nguyen, S. T.; Chen, C. F.; Chen, C. R.; Chiang, S. H.; Chang, L. Y.; Khin, L. V.

    2015-12-01

    Half of the world's population depends on rice for survival. Rice agriculture thus plays an important role in the developing world's economy. Vietnam is one of the largest rice producers and suppliers on earth and more than 80% of the exported rice was produced from the Mekong Delta region, which is situated in the southwestern Vietnam and encompasses approximately 40,000 km2. Changes in climate conditions could likely trigger the increase of insect populations and rice diseases, causing the potential loss of rice yields. Monitoring rice-farming activities through crop phenology detection can provide policymakers with timely strategies to mitigate possible impacts on the potential yield as well as rice grain exports to ensure food security for the region. The main objective of this study is to develop a logistic-based algorithm to investigate rice sowing and harvesting activities from the multi-temporal Moderate Resolution Imaging Spectroradiometer (MODIS)-Landsat fusion data. We processed the data for two main cropping seasons (i.e., winter-spring and summer-autumn seasons) through a three-step procedure: (1) MODIS-Landsat data fusion, (2) construction of the time-series enhanced vegetation index 2 (EVI2) data, (3) rice crop phenology detection. The EVI2 data derived from the fusion results between MODIS and Landsat data were compared with that of Landsat data indicated close correlation between the two datasets (R2 = 0.93). The time-series EVI2 data were processed using the double logistic method to detect the progress of sowing and harvesting activities in the region. The comparisons between the estimated sowing and harvesting dates and the field survey data revealed the root mean squared error (RMSE) values of 8.4 and 5.5 days for the winter-spring crop and 9.4 and 12.8 days for the summer-autumn crop, respectively. This study demonstrates the effectiveness of the double logistic-based algorithm for rice crop monitoring from temporal MODIS-Landsat fusion data

  12. Environmental Monitoring Networks Optimization Using Advanced Active Learning Algorithms

    NASA Astrophysics Data System (ADS)

    Kanevski, Mikhail; Volpi, Michele; Copa, Loris

    2010-05-01

    The problem of environmental monitoring networks optimization (MNO) belongs to one of the basic and fundamental tasks in spatio-temporal data collection, analysis, and modeling. There are several approaches to this problem, which can be considered as a design or redesign of monitoring network by applying some optimization criteria. The most developed and widespread methods are based on geostatistics (family of kriging models, conditional stochastic simulations). In geostatistics the variance is mainly used as an optimization criterion which has some advantages and drawbacks. In the present research we study an application of advanced techniques following from the statistical learning theory (SLT) - support vector machines (SVM) and the optimization of monitoring networks when dealing with a classification problem (data are discrete values/classes: hydrogeological units, soil types, pollution decision levels, etc.) is considered. SVM is a universal nonlinear modeling tool for classification problems in high dimensional spaces. The SVM solution is maximizing the decision boundary between classes and has a good generalization property for noisy data. The sparse solution of SVM is based on support vectors - data which contribute to the solution with nonzero weights. Fundamentally the MNO for classification problems can be considered as a task of selecting new measurement points which increase the quality of spatial classification and reduce the testing error (error on new independent measurements). In SLT this is a typical problem of active learning - a selection of the new unlabelled points which efficiently reduce the testing error. A classical approach (margin sampling) to active learning is to sample the points closest to the classification boundary. This solution is suboptimal when points (or generally the dataset) are redundant for the same class. In the present research we propose and study two new advanced methods of active learning adapted to the solution of

  13. Stress monitoring versus microseismic ruptures in an active deep mine

    NASA Astrophysics Data System (ADS)

    Tonnellier, Alice; Bouffier, Christian; Bigarré, Pascal; Nyström, Anders; Österberg, Anders; Fjellström, Peter

    2015-04-01

    monitoring data coming from the mine in quasi-real time and facilitates information exchanges and decision making for experts and stakeholders. On the basis of these data acquisition and sharing, preliminary analysis has been started to highlight whether stress variations and seismic sources behaviour might be directly bound with mine working evolution and could improve the knowledge on the equilibrium states inside the mine. Knowing such parameters indeed will be a potential solution to understand better the response of deep mining activities to the exploitation solicitations and to develop, if possible, methods to prevent from major hazards such as rock bursts and other ground failure phenomena.

  14. A process activity monitor for AOS/VS

    NASA Technical Reports Server (NTRS)

    Mckosky, R. A.; Lindley, S. W.; Chapman, J. S.

    1986-01-01

    With the ever increasing concern for computer security, users of computer systems are becoming more sensitive to unauthorized access. One of the initial security concerns for the Shuttle Management Information System was the problem of users leaving their workstations unattended while still connected to the system. This common habit was a concern for two reasons: it ties up resources unnecessarily and it opens the way for unauthorized access to the system. The Data General MV/10000 does not come equipped with an automatic time-out option on interactive peripherals. The purpose of this memorandum is to describe a system which monitors process activity on the system and disconnects those users who show no activity for some time quantum.

  15. Active sensors for health monitoring of aging aerospace structures

    SciTech Connect

    GIURGIUTIU,VICTOR; REDMOND,JAMES M.; ROACH,DENNIS P.; RACKOW,KIRK A.

    2000-03-08

    A project to develop non-intrusive active sensors that can be applied on existing aging aerospace structures for monitoring the onset and progress of structural damage (fatigue cracks and corrosion) is presented. The state of the art in active sensors structural health monitoring and damage detection is reviewed. Methods based on (a) elastic wave propagation and (b) electro-mechanical (NM) impedance technique are sighted and briefly discussed. The instrumentation of these specimens with piezoelectric active sensors is illustrated. The main detection strategies (E/M impedance for local area detection and wave propagation for wide area interrogation) are discussed. The signal processing and damage interpretation algorithms are tuned to the specific structural interrogation method used. In the high-frequency EIM impedance approach, pattern recognition methods are used to compare impedance signatures taken at various time intervals and to identify damage presence and progression from the change in these signatures. In the wave propagation approach, the acoustic-ultrasonic methods identifying additional reflection generated from the damage site and changes in transmission velocity and phase are used. Both approaches benefit from the use of artificial intelligence neural networks algorithms that can extract damage features based on a learning process. Design and fabrication of a set of structural specimens representative of aging aerospace structures is presented. Three built-up specimens, (pristine, with cracks, and with corrosion damage) are used. The specimen instrumentation with active sensors fabricated at the University of South Carolina is illustrated. Preliminary results obtained with the E/M impedance method on pristine and cracked specimens are presented.

  16. Active sensors for health monitoring of aging aerospace structures

    SciTech Connect

    GIURGIUTIU,VICTOR; REDMOND,JAMES M.; ROACH,DENNIS P.; RACKOW,KIRK A.

    2000-02-29

    A project to develop non-intrusive active sensors that can be applied on existing aging aerospace structures for monitoring the onset and progress of structural damage (fatigue cracks and corrosion) is presented. The state of the art in active sensors structural health monitoring and damage detection is reviewed. Methods based on (a) elastic wave propagation and (b) electro-mechanical (E/M) impedance technique are cited and briefly discussed. The instrumentation of these specimens with piezoelectric active sensors is illustrated. The main detection strategies (E/M impedance for local area detection and wave propagation for wide area interrogation) are discussed. The signal processing and damage interpretation algorithms are tuned to the specific structural interrogation method used. In the high-frequency E/M impedance approach, pattern recognition methods are used to compare impedance signatures taken at various time intervals and to identify damage presence and progression from the change in these signatures. In the wave propagation approach, the acousto-ultrasonic methods identifying additional reflection generated from the damage site and changes in transmission velocity and phase are used. Both approaches benefit from the use of artificial intelligence neural networks algorithms that can extract damage features based on a learning process. Design and fabrication of a set of structural specimens representative of aging aerospace structures is presented. Three built-up specimens (pristine, with cracks, and with corrosion damage) are used. The specimen instrumentation with active sensors fabricated at the University of South Carolina is illustrated. Preliminary results obtained with the E/M impedance method on pristine and cracked specimens are presented.

  17. Differential actigraphy for monitoring asymmetry in upper limb motor activities.

    PubMed

    Rabuffetti, M; Meriggi, P; Pagliari, C; Bartolomeo, P; Ferrarin, M

    2016-09-21

    Most applications of accelerometry-based actigraphy require a single sensor, properly located onto the body, to estimate, for example, the level of activity or the energy expenditure. Some approaches adopt a multi-sensor setup to improve those analyses or to classify different types of activity. The specific case of two symmetrically placed actigraphs allowing, by some kind of differential analysis, for the assessment of asymmetric motor behaviors, has been considered in relatively few studies. This article presents a novel method for differential actigraphy, which requires the synchronized measurements of two triaxial accelerometers (programmable eZ430-Chronos, Texas Instruments, USA) placed symmetrically on both wrists. The method involved the definition of a robust epoch-related activity index and its implementation on-board the adopted programmable platform. Finally, the activity recordings from both sensors allowed us to define a novel asymmetry index AR24 h ranging from  -100% (only the left arm moves) to  +100% (only the right arm moves) with null value marking a perfect symmetrical behavior. The accuracy of the AR24 h index was 1.3%. Round-the-clock monitoring on 31 healthy participants (20-79 years old, 10 left handed) provided for the AR24 h reference data (range  -5% to 21%) and a fairly good correlation to the clinical handedness index (r  =  0.66, p  <  0.001). A subset of 20 participants repeated the monitoring one week apart evidencing an excellent test-retest reliability (r  =  0.70, p  <  0.001). Such figures support future applications of the methodology for the study of pathologies involving motor asymmetries, such as in patients with motor hemisyndromes and, in general, for those subjects for whom a quantification of the asymmetry in daily motor performances is required to complement laboratory tests.

  18. Active Volcano Monitoring using a Space-based Hyperspectral Imager

    NASA Astrophysics Data System (ADS)

    Cipar, J. J.; Dunn, R.; Cooley, T.

    2010-12-01

    Active volcanoes occur on every continent, often in close proximity to heavily populated areas. While ground-based studies are essential for scientific research and disaster mitigation, remote sensing from space can provide rapid and continuous monitoring of active and potentially active volcanoes [Ramsey and Flynn, 2004]. In this paper, we report on hyperspectral measurements of Kilauea volcano, Hawaii. Hyperspectral images obtained by the US Air Force TacSat-3/ARTEMIS sensor [Lockwood et al, 2006] are used to obtain estimates of the surface temperatures for the volcano. ARTEMIS measures surface-reflected light in the visible, near-infrared, and short-wave infrared bands (VNIR-SWIR). The SWIR bands are known to be sensitive to thermal radiation [Green, 1996]. For example, images from the NASA Hyperion hyperspectral sensor have shown the extent of wildfires and active volcanoes [Young, 2009]. We employ the methodology described by Dennison et al, (2006) to obtain an estimate of the temperature of the active region of Kilauea. Both day and night-time images were used in the analysis. To improve the estimate, we aggregated neighboring pixels. The active rim of the lava lake is clearly discernable in the temperature image, with a measured temperature exceeding 1100o C. The temperature decreases markedly on the exterior of the summit crater. While a long-wave infrared (LWIR) sensor would be ideal for volcano monitoring, we have shown that the thermal state of an active volcano can be monitored using the SWIR channels of a reflective hyperspectral imager. References: Dennison, Philip E., Kraivut Charoensiri, Dar A. Roberts, Seth H. Peterson, and Robert O. Green (2006). Wildfire temperature and land cover modeling using hyperspectral data, Remote Sens. Environ., vol. 100, pp. 212-222. Green, R. O. (1996). Estimation of biomass fire temperature and areal extent from calibrated AVIRIS spectra, in Summaries of the 6th Annual JPL Airborne Earth Science Workshop, Pasadena, CA

  19. Evaluation of activity monitors in manual wheelchair users with paraplegia

    PubMed Central

    Hiremath, Shivayogi V.; Ding, Dan

    2011-01-01

    Objective The aim of this study was to evaluate the performance of SenseWear® (SW) and RT3 activity monitors (AMs) in estimating energy expenditure (EE) in manual wheelchair users (MWUs) with paraplegia for a variety of physical activities. Methods Twenty-four subjects completed four activities including resting, wheelchair propulsion, arm-ergometry exercise, and deskwork. The criterion EE was measured by a K4b2 portable metabolic cart. The EE estimated by the SW and RT3 were compared with the criterion EE by the absolute differences and absolute percentage errors. Intraclass correlations and the Bland and Altman plots were also used to assess the agreements between the two AMs and the metabolic cart. Correlations between the criterion EE and the estimated EE and sensors data from the AMs were evaluated. Results The EE estimation errors for the AMs varied from 24.4 to 125.8% for the SW and from 22.0 to 52.8% for the RT3. The intraclass correlation coefficients (ICCs) between the criterion EE and the EE estimated by the two AMs for each activity and all activities as a whole were considered poor with all the ICCs smaller than 0.75. Except for deskwork, the EE from the SW was more correlated to the criterion EE than the EE from the RT3. Conclusion The results indicate that neither of the AMs is an appropriate tool for quantifying physical activity in MWUs with paraplegia. However, the accuracy of EE estimation could be potentially improved by building new regression models based on wheelchair-related activities. PMID:21528634

  20. Clinical value of monitoring eosinophil activity in asthma.

    PubMed Central

    Koller, D Y; Herouy, Y; Götz, M; Hagel, E; Urbanek, R; Eichler, I

    1995-01-01

    To evaluate the use of eosinophil cationic protein (ECP) in monitoring disease activity in childhood asthma, serum ECP in 175 asthmatic children was assessed. Forty five patients with cystic fibrosis, 23 with lower respiratory tract infections (LRTI), and 87 healthy children were used as controls. Serum ECP concentrations (34.3 micrograms/l v 9.8 micrograms/l) were significantly higher in children with bronchial asthma than in healthy control subjects. In symptomatic patients with asthma serum ECP concentrations were increased compared with those from asymptomatic patients (40.2 micrograms/l v 14.4 micrograms/l), irrespective of treatment modalities (that is steroids, beta 2 agonists, or sodium cromoglycate). Moreover, atopy and infection appeared to be factors enhancing eosinophil activity in bronchial asthma as measured by serum ECP (58.4 micrograms/l v 36.8 micrograms/l and 68.8 micrograms/l v 42.2 micrograms/l, respectively). In a longitudinal trial, antiasthmatic treatment modalities (that is steroids) reduced serum ECP within four weeks (42.2 micrograms/l v 19.0 micrograms/l). In conclusion, the data indicate that (1) eosinophils also play a central part in childhood asthma; (2) serum concentrations of ECP in children with bronchial asthma are related to the disease severity and may thus be used for monitoring inflammation in childhood asthma; (3) eosinophil activity appears to be enhanced by atopy and infection; and (4) longitudinal measurements of serum ECP concentrations may be useful for optimising anti-inflammatory treatment in children with bronchial asthma. PMID:8554357

  1. 7 CFR 58.648 - Microbiological requirements for ice cream.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Microbiological requirements for ice cream. 58.648 Section 58.648 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... requirements for ice cream. The finished product shall contain not more than 50,000 bacteria per gram...

  2. 7 CFR 58.647 - Composition requirements for ice cream.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Composition requirements for ice cream. 58.647 Section 58.647 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... requirements for ice cream. See § 58.605(a)....

  3. 7 CFR 1005.16 - Fluid cream product.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Fluid cream product. 1005.16 Section 1005.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Regulating Handling Definitions § 1005.16 Fluid cream product. See § 1000.16....

  4. 7 CFR 1131.16 - Fluid cream product.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Fluid cream product. 1131.16 Section 1131.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Handling Definitions § 1131.16 Fluid cream product. See § 1000.16....

  5. 7 CFR 1030.16 - Fluid cream product.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Fluid cream product. 1030.16 Section 1030.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Regulating Handling Definitions § 1030.16 Fluid cream product. See § 1000.16....

  6. 7 CFR 1032.16 - Fluid cream product.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Fluid cream product. 1032.16 Section 1032.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Handling Definitions § 1032.16 Fluid cream product. See § 1000.16....

  7. 7 CFR 1007.16 - Fluid cream product.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Fluid cream product. 1007.16 Section 1007.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Handling Definitions § 1007.16 Fluid cream product. See § 1000.16....

  8. 7 CFR 1006.16 - Fluid cream product.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Fluid cream product. 1006.16 Section 1006.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Handling Definitions § 1006.16 Fluid cream product. See § 1000.16....

  9. 7 CFR 58.714 - Cream cheese, Neufchatel cheese.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Cream cheese, Neufchatel cheese. 58.714 Section 58.714 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Material § 58.714 Cream cheese, Neufchatel cheese. These cheeses when mixed with other foods, or used...

  10. 7 CFR 1001.16 - Fluid cream product.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Fluid cream product. 1001.16 Section 1001.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Handling Definitions § 1001.16 Fluid cream product. See § 1000.16....

  11. 7 CFR 1126.16 - Fluid cream product.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Fluid cream product. 1126.16 Section 1126.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Handling Definitions § 1126.16 Fluid cream product. See § 1000.16....

  12. 7 CFR 1124.16 - Fluid cream product.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Fluid cream product. 1124.16 Section 1124.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Regulating Handling Definitions § 1124.16 Fluid cream product. See § 1000.16....

  13. 21 CFR 524.981a - Fluocinolone acetonide cream.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Fluocinolone acetonide cream. 524.981a Section 524.981a Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... Fluocinolone acetonide cream. (a) Specifications. The drug contains 0.025 percent fluocinolone acetonide....

  14. 7 CFR 1033.16 - Fluid cream product.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Fluid cream product. 1033.16 Section 1033.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Handling Definitions § 1033.16 Fluid cream product. See § 1000.16....

  15. 7 CFR 1032.16 - Fluid cream product.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Fluid cream product. 1032.16 Section 1032.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... Handling Definitions § 1032.16 Fluid cream product. See § 1000.16....

  16. 7 CFR 1032.16 - Fluid cream product.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Fluid cream product. 1032.16 Section 1032.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Handling Definitions § 1032.16 Fluid cream product. See § 1000.16....

  17. 7 CFR 1032.16 - Fluid cream product.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Fluid cream product. 1032.16 Section 1032.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... Handling Definitions § 1032.16 Fluid cream product. See § 1000.16....

  18. 7 CFR 1032.16 - Fluid cream product.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Fluid cream product. 1032.16 Section 1032.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Handling Definitions § 1032.16 Fluid cream product. See § 1000.16....

  19. IDEEA activity monitor: validity of activity recognition for lying, reclining, sitting and standing.

    PubMed

    Jiang, Yuyu; Larson, Janet L

    2013-03-01

    Recent evidence demonstrates the independent negative effects of sedentary behavior on health, but there are few objective measures of sedentary behavior. Most instruments measure physical activity and are not validated as measures of sedentary behavior. The purpose of this study was to evaluate the validity of the IDEEA system's measures of sedentary and low-intensity physical activities: lying, reclining, sitting and standing. Thirty subjects, 14 men and 16 women, aged 23 to 77 years, body mass index (BMI) between 18 to 34 kg/m(2), participated in the study. IDEEA measures were compared to direct observation for 27 activities: 10 lying in bed, 3 lying on a sofa, 1 reclining in a lawn chair, 10 sitting and 3 standing. Two measures are reported, the percentage of activities accurately identified and the percentage of monitored time that was accurately labeled by the IDEEA system for all subjects. A total of 91.6% of all observed activities were accurately identified and 92.4% of the total monitored time was accurately labeled. The IDEEA system did not accurately differentiate between lying and reclining so the two activities were combined for calculating accuracy. Using this approach the IDEEA system accurately identified 96% of sitting activities for a total of 97% of the monitored sitting time, 99% and 99% for standing, 87% and 88% for lying in bed, 87% and 88% for lying on the sofa, and 83% and 83% for reclining on a lawn chair. We conclude that the IDEEA system accurately recognizes sitting and standing positions, but it is less accurate in identifying lying and reclining positions. We recommend combining the lying and reclining activities to improve accuracy. The IDEEA system enables researchers to monitor lying, reclining, sitting and standing with a reasonable level of accuracy and has the potential to advance the science of sedentary behaviors and low-intensity physical activities.

  20. Single-Molecule Electronic Monitoring of DNA Polymerase Activity

    NASA Astrophysics Data System (ADS)

    Marushchak, Denys O.; Pugliese, Kaitlin M.; Turvey, Mackenzie W.; Choi, Yongki; Gul, O. Tolga; Olsen, Tivoli J.; Rajapakse, Arith J.; Weiss, Gregory A.; Collins, Philip G.

    Single-molecule techniques can reveal new spatial and kinetic details of the conformational changes occurring during enzymatic catalysis. Here, we investigate the activity of DNA polymerases using an electronic single-molecule technique based on carbon nanotube transistors. Single molecules of the Klenow fragment (KF) of polymerase I were conjugated to the transistors and then monitored via fluctuations in electrical conductance. Continuous, long-term monitoring recorded single KF molecules incorporating up to 10,000 new bases into single-stranded DNA templates. The duration of individual incorporation events was invariant across all analog and native nucleotides, indicating that the precise structure of different base pairs has no impact on the timing of incorporation. Despite similar timings, however, the signal magnitudes generated by certain analogs reveal alternate conformational states that do not occur with native nucleotides. The differences induced by these analogs suggest that the electronic technique is sensing KF's O-helix as it tests the stability of nascent base pairs.

  1. Design, Synthesis, and Monitoring of Light-Activated Motorized Nanomachines

    NASA Astrophysics Data System (ADS)

    Chiang, Pinn-Tsong

    Our group has developed a family of single molecules termed nanocars, which are aimed at performing controllable motion on surfaces. In this work, a series of light-activated motorized nanomachines incorporated with a MHz frequency light-activated unidirectional rotary motor were designed and synthesized. We hope the light-activated motor can serve as the powering unit for the nanomachines, and perform controllable translational motion on surfaces or in solution. A series of motorized nanovehicles intended for scanning tunneling microscopy (STM) imaging were designed and synthesized. A p-carborane-wheeled motorized nanocar was synthesized and monitored by STM. Single-molecule imaging was accomplished on a Cu(111) surface. However, further manipulations did lead to motor induced lateral motion. We attributed this result to the strong molecule-surface interactions between the p-carborane-wheeled nanocar and the Cu(111) surface and possible energy transfer between the rotary motor and the Cu(111) surface. To fine-tune the molecule-surface interactions, an adamantane-wheeled motorized nanocar and a three-wheel nanoroadster were designed and synthesized. In addition, the STM substrates will be varied and different combinations of molecule-surface interactions will be studied. As a complimentary imaging method to STM, single-molecule fluorescence microscopy (SMFM) also provides single-molecule level resolution. Unlike STM experiment requires ultra-high vacuum and conductive substrate, SMFM experiment is conducted at ambient conditions and uses non-conductive substrate. This imaging method allows us to study another category of molecule-surface interactions. We plan to design a fluorescent motorized nanocar that is suitable for SMFM studies. However, both the motor and fluorophore are photochemically active molecules. In proximity, some undesired energy transfer or interference could occur. A cyanine 5- (cy5-) tagged motorized nanocar incorporated with the MHz motor was

  2. Multi-level continuous active source seismic monitoring (ML-CASSM): Application to shallow hydrofracture monitoring

    NASA Astrophysics Data System (ADS)

    Ajo Franklin, J. B.; Daley, T. M.; Butler-Veytia, B.; Peterson, J.; Gasperikova, E.; Hubbard, S. S.

    2010-12-01

    Induced subsurface processes occur over a wide variety of time scales ranging from seconds (e.g. fracture initiation) to days (e.g. unsteady multiphase flow) and weeks (e.g. induced mineral precipitation). Active source seismic monitoring has the potential to dynamically characterize such alterations and allow estimation of spatially localized rates. However, even optimal timelapse seismic surveys have limited temporal resolution due to both the time required to acquire a survey and the cost of continuous field deployment of instruments and personnel. Traditional timelapse surveys are also limited by experimental repeatability due to a variety of factors including geometry replication and near-surface conditions. Recent research has demonstrated the value of semi-permanently deployed seismic systems with fixed sources and receivers for use in monitoring a variety of processes including near-surface stress changes (Silver et.al. 2007), subsurface movement of supercritical CO2 (Daley et.al. 2007), and preseismic velocity changes in fault regions (Niu et. al. 2008). This strategy, referred to as continuous active source seismic monitoring (CASSM), allows both precise quantification of traveltime changes on the order of 1.1 x 10-7 s and temporal sampling on the order of minutes. However, as previously deployed, CASSM often sacrifices spatial resolution for temporal resolution with previous experiments including only a single source level. We present results from the first deployment of CASSM with a large number of source levels under automated control. Our system is capable of autonomously acquiring full tomographic datasets (10 sources, 72 receivers) in 3 minutes without human intervention, thus allowing active source seismic imaging (rather than monitoring) of processes with short durations. Because no sources or receivers are moved in the acquisition process, signal repeatability is excellent and subtle waveform changes can be interpreted with increased confidence

  3. Use of Small Fluorescent Molecules to Monitor Channel Activity

    NASA Astrophysics Data System (ADS)

    Jones, Sharon; Stringer, Sarah; Naik, Rajesh; Stone, Morley

    2001-03-01

    The Mechanosensitive channel of Large conductance (MscL) allows bacteria to rapidly adapt to changing environmental conditions such as osmolarity. The MscL channel opens in response to increases in membrane tension, which allows for the efflux of cytoplasmic constituents. Here we describe the cloning and expression of Salmonella typhimurium MscL (St-MscL). Using a fluorescence efflux assay, we demonstrate that efflux through the MscL channel during hypoosmotic shock can be monitored using endogenously produced fluorophores. In addition, we observe that thermal stimulation, i.e., heat shock, can also induce efflux through MscL. We present the first evidence of thermal activation of MscL efflux by heat shocking cells expressing the S. typhimurium protein variant. This finding has significant biosensor implications, especially for investigators exploring the use of channel proteins in biosensor applications. Thermal biosensors are relatively unexplored, but would have considerable commercial and military utility.

  4. Automatic Video System for Continues Monitoring of the Meteor Activity

    NASA Astrophysics Data System (ADS)

    Koten, Pavel; Fliegel, Karel; Vítek, Stanislav; Páta, Petr

    2011-05-01

    In this paper we present current progress in development of new observational instruments for the double station video experiment. The Meteor Automatic Imager and Analyser (MAIA) system is based on digital monochrome camera JAI CM-040 and well proved image intensifier XX1332. Both the observations as well as the data processing will be fully automatic. We are expecting the recorded data of better quality and both spatial and time resolution in comparison with currently used analogue system. The main goal of the MAIA project is to monitor activity of the meteor showers and sporadic meteor each night for the period of at least 3 years. First version of the system was already assembled and has been intensively tested in the optical laboratory. Optical properties were measured and the result confirmed our expectations according to image quality and resolution. First night sky observation was already carried out.

  5. Ice recrystallization inhibition in ice cream by propylene glycol monostearate.

    PubMed

    Aleong, J M; Frochot, S; Goff, H D

    2008-11-01

    The effectiveness of propylene glycol monostearate (PGMS) to inhibit ice recrystallization was evaluated in ice cream and frozen sucrose solutions. PGMS (0.3%) dramatically reduced ice crystal sizes in ice cream and in sucrose solutions frozen in a scraped-surface freezer before and after heat shock, but had no effect in quiescently frozen solutions. PGMS showed limited emulsifier properties by promoting smaller fat globule size distributions and enhanced partial coalescence in the mix and ice cream, respectively, but at a much lower level compared to conventional ice cream emulsifier. Low temperature scanning electron microscopy revealed highly irregular crystal morphology in both ice cream and sucrose solutions frozen in a scraped-surface freezer. There was strong evidence to suggest that PGMS directly interacts with ice crystals and interferes with normal surface propagation. Shear during freezing may be required for its distribution around the ice and sufficient surface coverage.

  6. Aerial monitoring in active mud volcano by UAV technique

    NASA Astrophysics Data System (ADS)

    Pisciotta, Antonino; Capasso, Giorgio; Madonia, Paolo

    2016-04-01

    UAV photogrammetry opens various new applications in the close range domain, combining aerial and terrestrial photogrammetry, but also introduces low-cost alternatives to the classical manned aerial photogrammetry. Between 2014 and 2015 tree aerial surveys have been carried out. Using a quadrotor drone, equipped with a compact camera, it was possible to generate high resolution elevation models and orthoimages of The "Salinelle", an active mud volcanoes area, located in territory of Paternò (South Italy). The main risks are related to the damages produced by paroxysmal events. Mud volcanoes show different cyclic phases of activity, including catastrophic events and periods of relative quiescence characterized by moderate activity. Ejected materials often are a mud slurry of fine solids suspended in liquids which may include water and hydrocarbon fluids, the bulk of released gases are carbon dioxide, with some methane and nitrogen, usually pond-shaped of variable dimension (from centimeters to meters in diameter). The scope of the presented work is the performance evaluation of a UAV system that was built to rapidly and autonomously acquire mobile three-dimensional (3D) mapping data in a volcanic monitoring scenario.

  7. Detection of physical activities using a physical activity monitor system for wheelchair users.

    PubMed

    Hiremath, Shivayogi V; Intille, Stephen S; Kelleher, Annmarie; Cooper, Rory A; Ding, Dan

    2015-01-01

    Availability of physical activity monitors for wheelchair users can potentially assist these individuals to track regular physical activity (PA), which in turn could lead to a healthier and more active lifestyle. Therefore, the aim of this study was to develop and validate algorithms for a physical activity monitoring system (PAMS) to detect wheelchair based activities. The PAMS consists of a gyroscope based wheel rotation monitor (G-WRM) and an accelerometer device (wocket) worn on the upper arm or on the wrist. A total of 45 persons with spinal cord injury took part in the study, which was performed in a structured university-based laboratory environment, a semi-structured environment at the National Veterans Wheelchair Games, and in the participants' home environments. Participants performed at least ten PAs, other than resting, taken from a list of PAs. The classification performance for the best classifiers on the testing dataset for PAMS-Arm (G-WRM and wocket on upper arm) and PAMS-Wrist (G-WRM and wocket on wrist) was 89.26% and 88.47%, respectively. The outcomes of this study indicate that multi-modal information from the PAMS can help detect various types of wheelchair-based activities in structured laboratory, semi-structured organizational, and unstructured home environments.

  8. Crystallization mechanisms in cream during ripening and initial butter churning.

    PubMed

    Buldo, Patrizia; Kirkensgaard, Jacob J K; Wiking, Lars

    2013-01-01

    The temperature treatment of cream is the time-consuming step in butter production. A better understanding of the mechanisms leading to partial coalescence, such as fat crystallization during ripening and churning of the cream, will contribute to optimization of the production process. In this study, ripening and churning of cream were performed in a rheometer cell and the mechanisms of cream crystallization during churning of the cream, including the effect of ripening time, were investigated to understand how churning time and partial coalescence are affected. Crystallization mechanisms were studied as function of time by differential scanning calorimetry, nuclear magnetic resonance and by X-ray scattering. Microstructure formation was investigated by small deformation rheology and static light scattering. The study demonstrated that viscosity measurements can be used to detect phase inversion of the emulsion during churning of the cream in a rheometer cell. Longer ripening time (e.g., 5h vs. 0 h) resulted in larger butter grains (91 vs. 52 µm), higher viscosity (5.3 vs. 1.3 Pa · s), and solid fat content (41 vs. 13%). Both ripening and churning time had an effect on the thermal behavior of the cream. Despite the increase in solid fat content, no further changes in crystal polymorphism and in melting behavior were observed after 1h of ripening and after churning. The churning time significantly decreased after 0.5h of ripening, from 22.9 min for the cream where no ripening was applied to 16.23 min. Therefore, the crystallization state that promotes partial coalescence (i.e., aggregation of butter grains) is obtained within the first hour of cream ripening at 10 °C. The present study adds knowledge on the fundamental processes of crystallization and polymorphism of milk fat occurring during ripening and churning of cream. In addition, the dairy industry will benefit from these insights on the optimization of butter manufacturing.

  9. INDIRECT MEASUREMENT OF BIOLOGICAL ACTIVITY TO MONITOR NATURAL ATTENUATION

    EPA Science Inventory

    The remediation of ground water contamination by natural attenuation, specifically biodegradation, requires continual monitoring. This research is aimed at improving methods for evaluating the long-term performance of Monitored Natural Attenuation (MNA), specifically changes in ...

  10. The treatment of melasma by silymarin cream

    PubMed Central

    2012-01-01

    Background Melasma is an acquired increased pigmentation of the skin characterized by symmetrical and confluent grey-brown patches usually on the areas of the face exposed to the sun. Silymarin strongly prevents photocarcinogenesis, and significantly prevented melanin production. The objectives of this study were the assessment of safety and efficacy of topical Silymain (SM) cream in a double-blind placebo controlled study for treatment of melasma patients. Methods Experimentally on 24 Albino rabbits were randomly divided into 4 equal groups. [A] No treatment, [B] received placebo, [C] treated with SM cream (0.1), & [D] treated by SM (0.2), were applied topically before UV sun light exposure for 30 days, assessed clinically & tissue pathology. Clinically on 96 adults diagnosed with melasma randomized to three equal groups to receive one of the tested drugs applied twice daily for 4 weeks, evaluated by the response; lesion size, melasma area and severity index score, Physician global assessment, and subjective assessment. Results The Clinical and histopathology observations were reduced significantly in SM groups. Clinically; all patients showed significant excellent pigment improvement & lesion size reduction with SM treatments from the 1st week. All patients were fully satisfied 100%. No side effects were observed. Conclusions Silymarin showed tremendous improvement of melasma in a dose-dependent manner, and was effective in prevention of skin damage caused by U.V. sunlight. It is a safe new candidate effective treatment for melasma. Trial registration Australian New Zealand Clinical Trials Registry - ACTRN12612000602820 PMID:23031632

  11. [Development of a wearable electrocardiogram monitor with recognition of physical activity scene].

    PubMed

    Wang, Zihong; Wu, Baoming; Yin, Jian; Gong, Yushun

    2012-10-01

    To overcome the problems of current electrocardiogram (ECG) tele-monitoring devices used for daily life, according to information fusion thought and by means of wearable technology, we developed a new type of wearable ECG monitor with the capability of physical activity recognition in this paper. The ECG monitor synchronously detected electrocardiogram signal and body acceleration signal, and recognized the scene information of physical activity, and finally determined the health status of the heart. With the advantages of accuracy for measurement, easy to use, comfort to wear, private feelings and long-term continuous in monitoring, this ECG monitor is quite fit for the heart-health monitoring in daily life.

  12. Determination of polybromodiphenyl ethers (PBDEs) in milk cream by gas chromatography-mass spectrometry.

    PubMed

    Kinani, Said; Bouchonnet, Stéphane; Abjean, Janine; Campargue, Christian

    2008-08-01

    An analytical method for polybromodiphenyl ethers (PBDEs) in milk cream has been optimized. The six PBDEs targeted were chosen on criteria of toxicity and occurrence in environmental matrices. Three methods of extraction were tested and compared in terms of lipid recovery yields and repeatability. The sample preparation process includes two steps: extraction by accelerated solvent extraction (ASE) and purification by solid phase extraction (SPE). The preferred method of extraction used a hexane/methylene chloride/methanol (5 : 2 : 1, v/v) solvent mixture. Three extraction cycles were carried out per sample at a temperature of 80 degrees C and a pressure of 1500 psi. The method was validated on milk cream samples spiked with the specified PBDEs. Recoveries for the whole sample preparation process (extraction and cleanup) for cream samples spiked at 10 and 100 ng g(-1) were greater than 80% (ranging from 81 to 106%) at both concentrations for BDE-99, -100, -153 and 154. Recoveries were lower (ranging from 65 to 75%) for BDE-28 and BDE-47. PBDEs were quantified by GC/MS detection with selected ion monitoring (SIM) using three ions formed by electron capture. The method was successfully tested on real samples.

  13. Using VHF Lightning Observations to Monitor Explosive Volcanic Activity

    NASA Astrophysics Data System (ADS)

    Behnke, S. A.; Thomas, R. J.; McNutt, S. R.; Krehbiel, P. R.; Rison, W.; Edens, H. E.

    2011-12-01

    Lightning is an integral part of explosive volcanic eruptions and volcanic lightning measurements are a useful tool for volcano monitoring. VHF measurements of volcanic lightning can be made remotely, at distances of up to 100 km. A strategically placed network of 6 or more VHF ground stations could locate lightning in eruption columns from several regional volcanoes, and a minimum of two stations could be used to monitor a single volcano. Such a network would be particularly useful for detection or confirmation of explosive activity in situations where volcanoes are remotely located, and thus lack visual observations, or are not well instrumented with seismic networks. Furthermore, clouds are fully transparent to VHF signals, making lightning detection possible even when weather obscures visual observations. Recent VHF observations of volcanic lightning at Augustine Volcano (Alaska, USA, 2006), Redoubt Volcano (Alaska, USA, 2009) and Eyjafjallajökull (Iceland, 2010) have shown that two basic types of VHF signals are observed during volcanic eruptions, one of which is unique to volcanic activity. The unique signal, referred to as a 'continual RF' signal, was caused by very high rates of small 'vent discharges' occurring directly above the vent in the eruption column and was unlike any observations of lightning in meteorological thunderstorms. Vent discharges were observed to begin immediately following an explosive eruption. The second type of signal is from conventional lightning discharges, such as upward directed 'near-vent lightning' and isolated 'plume lightning.' Near-vent lightning was observed to begin 1-2 minutes following the onset of an explosive eruption while plume lightning began 4 or more minutes after the onset. At Redoubt the plume lightning occurred at such high rates that it rivaled lightning rates of supercell thunderstorms on the Great Plains of the United States. While both types of lightning signals can be used as indicators that explosive

  14. Performance of a coincidence based blood activity monitor

    SciTech Connect

    Moses, W.W.

    1989-12-01

    A new device has been constructed that measures the positron emitting radio-tracer concentration in arterial blood by extracting blood with a peristaltic pump, then measuring the activity concentration by detecting coincident pairs of 511 keV photons with a pair of heavy inorganic scintillators attached to photomultiplier tubes. The sensitivity of this device is experimentally determined to be 610 counts/second per {mu}Ci/ml, and has a paralyzing dead time of 1.2 {mu}s, so is capable of measuring blood activity concentration as high as 1 mCi/ml. Its performance is compared to two other blood monitoring methods: discrete blood samples counted with a well counter and device that uses a plastic scintillator to directly detect positrons. The positron detection efficiency of this device for {sup 18}F is greater than the plastic scintillation counter, and also eliminates the radioisotope dependent correction factors necessary to convert count rate to absolute concentration. Coincident photon detection also has the potential of reducing the background compared to direct positron detection, thereby increasing the minimum detectable isotope concentration. 10 refs., 6 figs.

  15. Smart helmet: Monitoring brain, cardiac and respiratory activity.

    PubMed

    von Rosenberg, Wilhelm; Chanwimalueang, Theerasak; Goverdovsky, Valentin; Mandic, Danilo P

    2015-01-01

    The timing of the assessment of the injuries following a road-traffic accident involving motorcyclists is absolutely crucial, particularly in the events with head trauma. Standard apparatus for monitoring cardiac activity is usually attached to the limbs or the torso, while the brain function is routinely measured with a separate unit connected to the head-mounted sensors. In stark contrast to these, we propose an integrated system which incorporates the two functionalities inside an ordinary motorcycle helmet. Multiple fabric electrodes were mounted inside the helmet at positions featuring good contact with the skin at different sections of the head. The experimental results demonstrate that the R-peaks (and therefore the heart rate) can be reliably extracted from potentials measured with electrodes on the mastoids and the lower jaw, while the electrodes on the forehead enable the observation of neural signals. We conclude that various vital sings and brain activity can be readily recorded from the inside of a helmet in a comfortable and inconspicuous way, requiring only a negligible setup effort.

  16. Active Learning Framework for Non-Intrusive Load Monitoring: Preprint

    SciTech Connect

    Jin, Xin

    2016-05-16

    Non-Intrusive Load Monitoring (NILM) is a set of techniques that estimate the electricity usage of individual appliances from power measurements taken at a limited number of locations in a building. One of the key challenges in NILM is having too much data without class labels yet being unable to label the data manually for cost or time constraints. This paper presents an active learning framework that helps existing NILM techniques to overcome this challenge. Active learning is an advanced machine learning method that interactively queries a user for the class label information. Unlike most existing NILM systems that heuristically request user inputs, the proposed method only needs minimally sufficient information from a user to build a compact and yet highly representative load signature library. Initial results indicate the proposed method can reduce the user inputs by up to 90% while still achieving similar disaggregation performance compared to a heuristic method. Thus, the proposed method can substantially reduce the burden on the user, improve the performance of a NILM system with limited user inputs, and overcome the key market barriers to the wide adoption of NILM technologies.

  17. Treatment of toenail onychomycosis with 2% butenafine and 5% Melaleuca alternifolia (tea tree) oil in cream.

    PubMed

    Syed, T A; Qureshi, Z A; Ali, S M; Ahmad, S; Ahmad, S A

    1999-04-01

    The prevalence of onychomycosis, a superficial fungal infection that destroys the entire nail unit, is rising, with no satisfactory cure. The objective of this randomized, double-blind, placebo-controlled study was to examine the clinical efficacy and tolerability of 2% butenafine hydrochloride and 5% Melaleuca alternifolia oil incorporated in a cream to manage toenail onychomycosis in a cohort. Sixty outpatients (39 M, 21 F) aged 18-80 years (mean 29.6) with 6-36 months duration of disease were randomized to two groups (40 and 20), active and placebo. After 16 weeks, 80% of patients using medicated cream were cured, as opposed to none in the placebo group. Four patients in the active treatment group experienced subjective mild inflammation without discontinuing treatment. During follow-up, no relapse occurred in cured patients and no improvement was seen in medication-resistant and placebo participants.

  18. Targeted Proteomics Approaches To Monitor Microbial Activity In Basalt Aquifer

    NASA Astrophysics Data System (ADS)

    Paszczynski, A. J.; Paidisetti, R.

    2007-12-01

    Microorganisms play a major role in biogeochemical cycles of the Earth. Information regarding microbial community composition can be very useful for environmental monitoring since the short generation times of microorganisms allows them to respond rapidly to changing environmental conditions. Microbial mediated attenuation of toxic chemicals offers great potential for the restoration of contaminated environments in an ecologically acceptable manner. Current knowledge regarding the structure and functional activities of microbial communities is limited, but more information is being acquired every day through many genomic- and proteomic- based methods. As of today, only a small fraction of the Earth's microorganisms has been cultured, and so most of the information regarding the biodegradation and therapeutic potentials of these uncultured microorganisms remains unknown. Sequence analysis of DNA and/or RNA has been used for identifying specific microorganisms, to study the community composition, and to monitor gene expression providing limited information about metabolic state of given microbial system. Proteomic studies can reveal information regarding the real-time metabolic state of the microbial communities thereby aiding in understanding their interaction with the environment. In research described here the involvement of microbial communities in the degradation of anthropogenic contaminants such as trichloroethylene (TCE) was studied using mass spectrometry-based proteomics. The co- metabolic degradation of TCE in the groundwater of the Snake River Plain Aquifer at the Test Area North (TAN) site of Idaho National Laboratory (INL) was monitored by the characterization of peptide sequences of enzymes such as methane monooxygenases (MMOs). MMOs, expressed by methanotrophic bacteria are involved in the oxidation of methane and non-specific co-metabolic oxidation of TCE. We developed a time- course cell lysis method to release proteins from complex microbial

  19. 7 CFR 58.2825 - United States Standard for ice cream.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false United States Standard for ice cream. 58.2825 Section... DAIRY PRODUCTS 1 United States Department of Agriculture Standard for Ice Cream § 58.2825 United States Standard for ice cream. (a) Ice cream shall contain at least 1.6 pounds of total solids to the...

  20. A bioluminescent caspase-1 activity assay rapidly monitors inflammasome activation in cells.

    PubMed

    O'Brien, Martha; Moehring, Danielle; Muñoz-Planillo, Raúl; Núñez, Gabriel; Callaway, Justin; Ting, Jenny; Scurria, Mike; Ugo, Tim; Bernad, Laurent; Cali, James; Lazar, Dan

    2017-03-04

    Inflammasomes are protein complexes induced by diverse inflammatory stimuli that activate caspase-1, resulting in the processing and release of cytokines, IL-1β and IL-18, and pyroptosis, an immunogenic form of cell death. To provide a homogeneous method for detecting caspase-1 activity, we developed a bioluminescent, plate-based assay that combines a substrate, Z-WEHD-aminoluciferin, with a thermostable luciferase in an optimized lytic reagent added directly to cultured cells. Assay specificity for caspase-1 is conferred by inclusion of a proteasome inhibitor in the lytic reagent and by use of a caspase-1 inhibitor to confirm activity. This approach enables a specific and rapid determination of caspase-1 activation. Caspase-1 activity is stable in the reagent thereby providing assay convenience and flexibility. Using this assay system, caspase-1 activation has been determined in THP-1 cells following treatment with α-hemolysin, LPS, nigericin, gramicidin, MSU, R848, Pam3CSK4, and flagellin. Caspase-1 activation has also been demonstrated in treated J774A.1 mouse macrophages, bone marrow-derived macrophages (BMDMs) from mice, as well as in human primary monocytes. Caspase-1 activity was not detected in treated BMDMs derived from Casp1(-/-) mice, further confirming the specificity of the assay. Caspase-1 activity can be measured directly in cultured cells using the lytic reagent, or caspase-1 activity released into medium can be monitored by assay of transferred supernatant. The caspase-1 assay can be multiplexed with other assays to monitor additional parameters from the same cells, such as IL-1β release or cell death. The caspase-1 assay in combination with a sensitive real-time monitor of cell death allows one to accurately establish pyroptosis. This assay system provides a rapid, convenient, and flexible method to specifically and quantitatively monitor caspase-1 activation in cells in a plate-based format. This will allow a more efficient and effective

  1. Levels of nickel and other potentially allergenic metals in Ni-tested commercial body creams.

    PubMed

    Bocca, B; Forte, G; Petrucci, F; Cristaudo, A

    2007-09-03

    It is extensively well-known that Ni and other metals occurring as impurities in cosmetic products might give rise to contact dermatitis in subjects with pre-existing allergy. The present study on the content of 13 metals (Cd, Co, Cr, Cu, Hg, Ir, Mn, Ni, Pb, Pd, Pt, Rh, and V) in moisturizing creams, labelled as "Ni-tested" (i.e., Ni content <100 ng g(-1)) and available on the Italian market, provides a basis for assessing their safety for consumers. Quantification of metals was performed by sector field inductively coupled plasma mass spectrometry after microwave-assisted acid digestion of products. The developed method had limits of quantification less than 0.8 ng g(-1) for all the elements; recovery was in the interval 88% (Cd, Co) to 110% (Hg), and precision was always under 7%. Nickel was present in all the products with levels between 17.5 and 153 ng g(-1); three skin creams were slightly above the concentration reported on the label. The other elements were at levels below 1 microg g(-1). The highest concentrations, in ng g(-1), of Co, Cr, Cu, and Mn were 222, 303, 51.2, and 59.9, respectively. Mean Cd, Pb, and V were below 5 ng g(-1), while Hg was absent in all the samples. Among the new emergent allergens, Ir and Rh were in traces or even undetectable, while Pt had levels of 2.65 and 6.28 ng g(-1) in two creams and Pd was equal to 1.07 ng g(-1) in one product. The overall results are below the sensitizing limit proposed for consumer products and, thus, probably have no significant toxicological effects. Nevertheless, some creams presented amounts of Co and Cr comparable to those of Ni and therefore they have to be monitored in consideration of their cross-reactivity as well.

  2. Skin protection creams in medical settings: successful or evil?

    PubMed Central

    Xhauflaire-Uhoda, Emmanuelle; Macarenko, Elena; Denooz, Raphaël; Charlier, Corinne; Piérard, Gérald E

    2008-01-01

    Background Chronic exposure to mild irritants including cleansing and antiseptic products used for hand hygiene generates insults to the skin. To avoid unpleasant reactions, skin protection creams are commonly employed, but some fail to afford protection against a variety of xenobiotics. In this study, two skin protection creams were assayed comparatively looking for a protective effect if any against a liquid soap and an alcohol-based gel designed for hand hygiene in medical settings. Methods Corneosurfametry and corneoxenometry are two in vitro bioessays which were selected for their good reproducibility, sensitivity and ease of use. A Kruskal-Wallis ANOVA test followed by the Dunn test was realized to compare series of data obtained. Results Significant differences in efficacy were obtained between the two assayed skin protection creams. One of the two tested creams showed a real protective effect against mild irritants, but the other tested cream presented an irritant potential in its application with mild irritants. Conclusion The differences observed for the two tested skin protection creams were probably due to their galenic composition and their possible interactions with the offending products. As a result, the present in vitro bioassays showed contrasted effects of the creams corresponding to either a protective or an irritant effect on human stratum corneum. PMID:18655702

  3. Geophysical Monitoring of Microbial Activity within a Wetland Soil

    NASA Astrophysics Data System (ADS)

    O'Brien, M.; Zhang, C.; Ntarlagiannis, D.; Slater, L.; Yee, N.

    2007-05-01

    We performed Induced Polarization (IP) and Self Potential (SP) measurements to record the geoelectrical signatures of microbial activity within a wetland soil. The experiment was conducted in laboratory, utilizing an open flow column set up. Soil samples from Kearny Marsh (KM), a shallow water wetland, were collected and stored at 4o Celsius prior to the start of the experiment. Two columns were dry packed with a mix of KM soil and sterile Ottawa sand (50% by weight). One column was sterilized and used as a control while the other column retained the biologically active soil sample. Both columns were saturated with a minimal salts medium capable of supporting microbial life; after saturation, a steady flow rate of one pore volume per day was maintained throughout the experiment. Ambient temperature and pressure changes (at the inflow and outflow of each column) were continuously monitored throughout the experiment. Common geochemical parameters, such as Eh, pH, and fluid conductivity were measured at the inflow and outflow of each column at regular intervals. IP and SP responses were continuously recorded on both columns utilizing a series of electrodes along the column length; additionally for the SP measurements we used a reference electrode at the inflow tube. Strong SP anomalies were observed for all the locations along the active column. Black visible mineral precipitant also formed in the active column. The observed precipitation coincided with the times that SP anomalies developed at each electrode position. These responses are associated with microbial induced sulfide mineralization. We interpret the SP signal as the result of redox processes associated with this mineralization driven by gradients in ionic concentration and mobility within the column, similar to a galvanic cell mechanism. IP measurements show no correlation with these visual and SP responses. Destructive analysis of the samples followed the termination of the experiment. Scanning electron

  4. Physical Activity Measured by Physical Activity Monitoring System Correlates with Glucose Trends Reconstructed from Continuous Glucose Monitoring

    PubMed Central

    Zecchin, Chiara; Facchinetti, Andrea; Sparacino, Giovanni; Dalla Man, Chiara; Manohar, Chinmay; Levine, James A.; Basu, Ananda; Kudva, Yogish C.

    2013-01-01

    Abstract Background In type 1 diabetes mellitus (T1DM), physical activity (PA) lowers the risk of cardiovascular complications but hinders the achievement of optimal glycemic control, transiently boosting insulin action and increasing hypoglycemia risk. Quantitative investigation of relationships between PA-related signals and glucose dynamics, tracked using, for example, continuous glucose monitoring (CGM) sensors, have been barely explored. Subjects and Methods In the clinic, 20 control and 19 T1DM subjects were studied for 4 consecutive days. They underwent low-intensity PA sessions daily. PA was tracked by the PA monitoring system (PAMS), a system comprising accelerometers and inclinometers. Variations on glucose dynamics were tracked estimating first- and second-order time derivatives of glucose concentration from CGM via Bayesian smoothing. Short-time effects of PA on glucose dynamics were quantified through the partial correlation function in the interval (0, 60 min) after starting PA. Results Correlation of PA with glucose time derivatives is evident. In T1DM, the negative correlation with the first-order glucose time derivative is maximal (absolute value) after 15 min of PA, whereas the positive correlation is maximal after 40–45 min. The negative correlation between the second-order time derivative and PA is maximal after 5 min, whereas the positive correlation is maximal after 35–40 min. Control subjects provided similar results but with positive and negative correlation peaks anticipated of 5 min. Conclusions Quantitative information on correlation between mild PA and short-term glucose dynamics was obtained. This represents a preliminary important step toward incorporation of PA information in more realistic physiological models of the glucose–insulin system usable in T1DM simulators, in development of closed-loop artificial pancreas control algorithms, and in CGM-based prediction algorithms for generation of hypoglycemic alerts. PMID

  5. 40 CFR 62.15275 - How do I monitor the injection rate of activated carbon?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... activated carbon? 62.15275 Section 62.15275 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... August 30, 1999 Other Monitoring Requirements § 62.15275 How do I monitor the injection rate of activated carbon? If your municipal waste combustion unit uses activated carbon to control dioxins/furans...

  6. 40 CFR 62.15275 - How do I monitor the injection rate of activated carbon?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... activated carbon? 62.15275 Section 62.15275 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... August 30, 1999 Other Monitoring Requirements § 62.15275 How do I monitor the injection rate of activated carbon? If your municipal waste combustion unit uses activated carbon to control dioxins/furans...

  7. 40 CFR 62.15275 - How do I monitor the injection rate of activated carbon?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... activated carbon? 62.15275 Section 62.15275 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... August 30, 1999 Other Monitoring Requirements § 62.15275 How do I monitor the injection rate of activated carbon? If your municipal waste combustion unit uses activated carbon to control dioxins/furans...

  8. 40 CFR 62.15275 - How do I monitor the injection rate of activated carbon?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... activated carbon? 62.15275 Section 62.15275 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... August 30, 1999 Other Monitoring Requirements § 62.15275 How do I monitor the injection rate of activated carbon? If your municipal waste combustion unit uses activated carbon to control dioxins/furans...

  9. 40 CFR 62.15275 - How do I monitor the injection rate of activated carbon?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... activated carbon? 62.15275 Section 62.15275 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... August 30, 1999 Other Monitoring Requirements § 62.15275 How do I monitor the injection rate of activated carbon? If your municipal waste combustion unit uses activated carbon to control dioxins/furans...

  10. Lunar Dust and Lunar Simulant Activation and Monitoring

    NASA Technical Reports Server (NTRS)

    Wallace, W. T.; Hammond, D. K.; Jeevarajan, A. S.

    2008-01-01

    . Respir. Dis. 138 (1988) 1213-1219). The size and cost of these instruments makes them unattractive for the monitoring of lunar dust activity. A more suitable technique is based on the change in fluorescence of a molecule upon reaction with a hydroxyl radical (or other radical species). Fluorescence instruments are much less costly and bulky than ESR spectrometers, and small fluorescence sensors for space missions have already been developed (F. Gao, et al., J. Biomed. Opt. 10 (2005) 054005). For the current fluorescence studies, the terephthalate molecule has been chosen for monitoring the production of hydroxyl radicals in solution. As shown in Scheme 1, the reaction between the non-fluorescent terephthalate molecule and a hydroxyl radical produces the highly-fluorescent 2-hydroxyterephthalate molecule.

  11. Jovian dust streams: A monitor of Io's volcanic plume activity

    USGS Publications Warehouse

    Kruger, H.; Geissler, P.; Horanyi, M.; Graps, A.L.; Kempf, S.; Srama, R.; Moragas-Klostermeyer, G.; Moissl, R.; Johnson, T.V.; Grun, E.

    2003-01-01

    Streams of high speed dust particles originate from Jupiter's moon Io. After release from Io, the particles collect electric charges in the Io plasma torus, gain energy from the co-rotating electric field of Jupiter's magnetosphere, and leave the Jovian system into interplanetary space with escape speeds over 200 km s-1. The Galileo spacecraft has continuously monitored the dust streams during 34 revolutions about Jupiter between 1996 and 2002. The observed dust fluxes exhibit large orbit-to-orbit variability due to systematic and stochastic changes. After removal of the systematic variations, the total dust emission rate of Io has been calculated. It varies between 10-3 and 10 kg s-1, and is typically in the range of 0.1 to 1 kg s-1. We compare the dust emission rate with other markers of volcanic activity on Io like large-area surface changes caused by volcanic deposits and sightings of volcanic plumes. Copyright 2003 by the American Geophysical Union.

  12. Apollo Director Phillips Monitors Apollo 11 Pre-Launch Activities

    NASA Technical Reports Server (NTRS)

    1969-01-01

    From the Kennedy Space Flight Center (KSC) control room, Apollo Program Director Lieutenant General Samuel C. Phillips monitors pre-launch activities for Apollo 11. The Apollo 11 mission, the first lunar landing mission, launched from the KSC in Florida via the Marshall Space Flight Center (MSFC) developed Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Aboard the space craft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. (Buzz) Aldrin Jr., Lunar Module (LM) pilot. The CM, 'Columbia', piloted by Collins, remained in a parking orbit around the Moon while the LM, 'Eagle'', carrying astronauts Armstrong and Aldrin, landed on the Moon. On July 20, 1969, Armstrong was the first human to ever stand on the lunar surface, followed by Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

  13. Laser activated nanothermolysis of leukemia cells monitored by photothermal microscopy

    NASA Astrophysics Data System (ADS)

    Lapotko, Dmitri; Lukianova, Ekaterina; Shnip, Alexander; Zheltov, George; Potapnev, Michail; Savitsky, Valeriy; Klimovich, Olga; Oraevsky, Alexander

    2005-04-01

    We are developing new diagnostic and therapeutic technologies for leukemia based on selective targeting of leukemia cells with gold nanoparticles and thermomechanical destruction of the tumor cells with laser-induced microbubbles. Clusters of spherical gold nanoparticles that have strong optical absorption of laser pulses at 532 nm served as nucleation sites of vapor microbubbles. The nanoparticles were targeted selectively to leukemia cells using leukemia-specific surface receptors and a set of two monoclonal antibodies. Application of a primary myeloid-specific antibody to tumor cells followed by targeting the cells with 30-nm nanoparticles conjugated with a secondary antibody (IgG) resulted in formation of nanoparticulate clusters due to aggregation of IgGs. Formation of clusters resulted in substantial decrease of the damage threshold for target cells. The results encourage development of Laser Activated Nanothermolysis as a Cell Elimination Therapy (LANCET) for leukemia. The proposed technology can be applied separately or in combination with chemotherapy for killing leukemia cells without damage to other blood cells. Potential applications include initial reduction of concentration of leukemia cells in blood prior to chemotherapy and treatment of residual tumor cells after the chemotherapy. Laser-induced bubbles in individual cells and cell damage were monitored by analyzing profile of photothermal response signals over the entire cell after irradiation with a single 10-ns long laser pulse. Photothermal microscopy was utilized for imaging formation of microbubbles around nanoparticulate clusters.

  14. Cooperative wireless network control based health and activity monitoring system.

    PubMed

    Prakash, R; Ganesh, A Balaji; Girish, Siva V

    2016-10-01

    A real-time cooperative communication based wireless network is presented for monitoring health and activity of an end-user in their environment. The cooperative communication offers better energy consumption and also an opportunity to aware the current location of a user non-intrusively. The link between mobile sensor node and relay node is dynamically established by using Received Signal Strength Indicator (RSSI) and Link Quality Indicator (LQI) based on adaptive relay selection scheme. The study proposes a Linear Acceleration based Transmission Power Decision Control (LA-TPDC) algorithm to further enhance the energy efficiency of cooperative communication. Further, the occurrences of false alarms are carefully prevented by introducing three stages of sequential warning system. The real-time experiments are carried-out by using the nodes, namely mobile sensor node, relay nodes and a destination node which are indigenously developed by using a CC430 microcontroller integrated with an in-built transceiver at 868 MHz. The wireless node performance characteristics, such as energy consumption, Signal-Noise ratio (SNR), Bit Error Rate (BER), Packet Delivery Ratio (PDR) and transmission offset are evaluated for all the participated nodes. The experimental results observed that the proposed linear acceleration based transmission power decision control algorithm almost doubles the battery life time than energy efficient conventional cooperative communication.

  15. Step detection and activity recognition accuracy of seven physical activity monitors.

    PubMed

    Storm, Fabio A; Heller, Ben W; Mazzà, Claudia

    2015-01-01

    The aim of this study was to compare the seven following commercially available activity monitors in terms of step count detection accuracy: Movemonitor (Mc Roberts), Up (Jawbone), One (Fitbit), ActivPAL (PAL Technologies Ltd.), Nike+ Fuelband (Nike Inc.), Tractivity (Kineteks Corp.) and Sensewear Armband Mini (Bodymedia). Sixteen healthy adults consented to take part in the study. The experimental protocol included walking along an indoor straight walkway, descending and ascending 24 steps, free outdoor walking and free indoor walking. These tasks were repeated at three self-selected walking speeds. Angular velocity signals collected at both shanks using two wireless inertial measurement units (OPAL, ADPM Inc) were used as a reference for the step count, computed using previously validated algorithms. Step detection accuracy was assessed using the mean absolute percentage error computed for each sensor. The Movemonitor and the ActivPAL were also tested within a nine-minute activity recognition protocol, during which the participants performed a set of complex tasks. Posture classifications were obtained from the two monitors and expressed as a percentage of the total task duration. The Movemonitor, One, ActivPAL, Nike+ Fuelband and Sensewear Armband Mini underestimated the number of steps in all the observed walking speeds, whereas the Tractivity significantly overestimated step count. The Movemonitor was the best performing sensor, with an error lower than 2% at all speeds and the smallest error obtained in the outdoor walking. The activity recognition protocol showed that the Movemonitor performed best in the walking recognition, but had difficulty in discriminating between standing and sitting. Results of this study can be used to inform choice of a monitor for specific applications.

  16. Step Detection and Activity Recognition Accuracy of Seven Physical Activity Monitors

    PubMed Central

    Storm, Fabio A.; Heller, Ben W.; Mazzà, Claudia

    2015-01-01

    The aim of this study was to compare the seven following commercially available activity monitors in terms of step count detection accuracy: Movemonitor (Mc Roberts), Up (Jawbone), One (Fitbit), ActivPAL (PAL Technologies Ltd.), Nike+ Fuelband (Nike Inc.), Tractivity (Kineteks Corp.) and Sensewear Armband Mini (Bodymedia). Sixteen healthy adults consented to take part in the study. The experimental protocol included walking along an indoor straight walkway, descending and ascending 24 steps, free outdoor walking and free indoor walking. These tasks were repeated at three self-selected walking speeds. Angular velocity signals collected at both shanks using two wireless inertial measurement units (OPAL, ADPM Inc) were used as a reference for the step count, computed using previously validated algorithms. Step detection accuracy was assessed using the mean absolute percentage error computed for each sensor. The Movemonitor and the ActivPAL were also tested within a nine-minute activity recognition protocol, during which the participants performed a set of complex tasks. Posture classifications were obtained from the two monitors and expressed as a percentage of the total task duration. The Movemonitor, One, ActivPAL, Nike+ Fuelband and Sensewear Armband Mini underestimated the number of steps in all the observed walking speeds, whereas the Tractivity significantly overestimated step count. The Movemonitor was the best performing sensor, with an error lower than 2% at all speeds and the smallest error obtained in the outdoor walking. The activity recognition protocol showed that the Movemonitor performed best in the walking recognition, but had difficulty in discriminating between standing and sitting. Results of this study can be used to inform choice of a monitor for specific applications. PMID:25789630

  17. 7 CFR 58.336 - Frequency of sampling for quality control of cream, butter and related products.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., butter and related products. 58.336 Section 58.336 Agriculture Regulations of the Department of... of sampling for quality control of cream, butter and related products. (a) Microbiological. Samples... from the butter as often as is necessary to aid in the control of lipase activity. (d) Other...

  18. Ice cream and orbifold Riemann-Roch

    NASA Astrophysics Data System (ADS)

    Buckley, Anita; Reid, Miles; Zhou, Shengtian

    2013-06-01

    We give an orbifold Riemann-Roch formula in closed form for the Hilbert series of a quasismooth polarized n-fold (X,D), under the assumption that X is projectively Gorenstein with only isolated orbifold points. Our formula is a sum of parts each of which is integral and Gorenstein symmetric of the same canonical weight; the orbifold parts are called ice cream functions. This form of the Hilbert series is particularly useful for computer algebra, and we illustrate it on examples of {K3} surfaces and Calabi-Yau 3-folds. These results apply also with higher dimensional orbifold strata (see [1] and [2]), although the precise statements are considerably trickier. We expect to return to this in future publications.

  19. Cadence Feedback With ECE PEDO to Monitor Physical Activity Intensity

    PubMed Central

    Ardic, Fusun; Göcer, Esra

    2016-01-01

    Abstract The purpose of this study was to examine the monitoring capabilities of the equipment for clever exercise pedometer (ECE PEDO) that provides audible feedback when the person exceeds the upper and lower limits of the target step numbers per minute and to compare step counts with Yamax SW-200 (YX200) as the criterion pedometer. A total of 30 adult volunteers (15 males and 15 females) were classified as normal weight (n = 10), overweight (n = 10), and obese (n = 10). After the submaximal exercise test on a treadmill, the moderate intensity for walking was determined by using YX200 pedometer and then the number of steps taken in a minute was measured. Lower and upper limits of steps per minute (cadence) were recorded in ECE PEDO providing audible feedback when the person's walking speed gets out of the limits. Volunteers walked for 30 minutes in the individual step count range by attaching the ECE PEDO and YX200 pedometer on both sides of the waist belt in the same session. Step counts of the volunteers were recorded. Wilcoxon, Spearman correlation, and Bland–Altman analyses were performed to show the relationship and agreement between the results of 2 devices. Subjects took an average of 3511 ± 426 and 3493 ± 399 steps during 30 minutes with ECE PEDO and criterion pedometer, respectively. About 3500 steps taken by ECE PEDO reflected that this pedometer has capability of identifying steps per minute to meet moderate intensity of physical activity. There was a strong correlation between step counts of both devices (P < 0.001, r = 0.96). Correlations across all three BMI categories and both sex remained consistently high ranging from 0.92 to 0.95. There was a high level of agreement between the ECE PEDO and YX200 pedometer in the Bland–Altman analysis. Although both devices showed a strong similarity in counting steps, the ECE PEDO provides monitoring of intensity such that a person can walk in a specified time with a

  20. Proposal and pharmacotechnical study of a modern dermo-pharmaceutical formulation for cold cream.

    PubMed

    Jiménez Soriano, M M; Fresno Contreras, M J; Sellés Flores, E

    1996-06-01

    Cold-Creams have been used since the times of Galen (II cA.D.) as dermo-pharmaceutical and cosmetic emulsions. This paper proposes a modern Cold-Creams formulation with variations to improve both the formula as well as the properties and applications of the traditional cerates. Basically, a modern self-emulsionable excipient with isopropyl myristate is proposed. This substance is completely analysed from the galenic and pharmaco-technical viewpoints and the analysis is completed with a study of cosmetic or dermo-pharmaceutical effectiveness and topical application on skin. The results clearly show the advantages of the new formula which are: it is easy and comfortable to prepare, very adequate for cosmetology with satisfactory stability and rheological qualities and a high degree of moisture/emollient power make it appropriate as a vehicle for the active principle in Dermopharmacy and Cosmetology.

  1. Increasing the protein content of ice cream.

    PubMed

    Patel, M R; Baer, R J; Acharya, M R

    2006-05-01

    Vanilla ice cream was made with a mix composition of 10.5% milk fat, 10.5% milk SNF, 12% beet sugar, and 4% corn syrup solids. None of the batches made contained stabilizer or emulsifier. The control (treatment 1) contained 3.78% protein. Treatments 2 and 5 contained 30% more protein, treatments 3 and 6 contained 60% more protein, and treatments 4 and 7 contained 90% more protein compared with treatment 1 by addition of whey protein concentrate or milk protein concentrate powders, respectively. In all treatments, levels of milk fat, milk SNF, beet sugar, and corn syrup solids were kept constant at 37% total solids. Mix protein content for treatment 1 was 3.78%, treatment 2 was 4.90%, treatment 5 was 4.91%, treatments 3 and 6 were 6.05%, and treatments 4 and 7 were 7.18%. This represented a 29.89, 60.05, 89.95, 29.63, 60.05, and 89.95% increase in protein for treatment 2 through treatment 7 compared with treatment 1, respectively. Milk protein level influenced ice crystal size; with increased protein, the ice crystal size was favorably reduced in treatments 2, 4, and 5 and was similar in treatments 3, 6, and 7 compared with treatment 1. At 1 wk postmanufacture, overall texture acceptance for all treatments was more desirable compared with treatment 1. When evaluating all parameters, treatment 2 with added whey protein concentrate and treatments 5 and 6 with added milk protein concentrate were similar or improved compared with treatment 1. It is possible to produce acceptable ice cream with higher levels of protein.

  2. The anti-inflammatory effect of organo-heparinoid cream after bilateral mandibular osteotomies.

    PubMed

    Sindet-Pedersen, S; Lund, E; Simonsen, E K; Stenbjerg, S

    1989-02-01

    The aim of the present study was to compare the effect on swelling after bilateral osteotomies of the mandible of treatment with organo-heparinoid (Hirudoid) cream and that of a placebo cream. 12 patients (7 female, 5 male), median age of 29.5 years, were included in the study. 5 patients received bilateral sagittal-split procedures for symmetrical mandibular advancement, and 7 patients received bilateral mandibular osteotomies for symmetrical mandibular set-back. Each of the 2 operated sides were randomized for treatment with active medication or placebo; 1.5 g of the active- or placebo cream were carefully rubbed into the skin above the masseteric muscle 4 times a day for 4 days. Periodic identical CT-scans were performed to evaluate swelling; patients were CT-scanned preoperatively and once or twice postoperatively. 3 variables were used to assess the swelling: (1) thickness of the subcutis; (2) maximum thickness of the masseteric muscle; (3) cross-sectional area of the soft tissues facial to the ramus of the mandible. No significant differences in postoperative swelling could be demonstrated between the 2 treatments. There were no detectable systemic effects of the treatment with organo-heparinoid.

  3. Measurement of activity in older adults: reliability and validity of the Step Activity Monitor.

    PubMed

    Resnick, B; Nahm, E S; Orwig, D; Zimmerman, S S; Magaziner, J

    2001-01-01

    The purpose of this study was to test the reliability and validity of the Step Activity Monitor (SAM) when used with older adults. A total of 30 subjects with a mean age of 86 +/- 6.1 participated in the study. Sixty one-minute walks were measured with the SAM, and two observers visually counted steps. Four participants wore the SAM for 6 to 48 hours and maintained activity diaries. The intraclass correlation for the SAM recordings was R = .84. There was an overall step counting accuracy of 96%. The diaries supported the SAM data for those who wore the SAM for extended periods. The SAM is an easy to use, comfortable, valid, and reliable measure of activity in older adults and particularly may be useful to triangulate measurement of activity in these individuals.

  4. 7 CFR 58.714 - Cream cheese, Neufchatel cheese.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Specifications for Dairy Plants Approved for USDA Inspection and Grading Service 1 Quality Specifications for Raw Material § 58.714 Cream cheese, Neufchatel cheese. These cheeses when mixed with other foods, or used...

  5. 7 CFR 58.714 - Cream cheese, Neufchatel cheese.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Specifications for Dairy Plants Approved for USDA Inspection and Grading Service 1 Quality Specifications for Raw Material § 58.714 Cream cheese, Neufchatel cheese. These cheeses when mixed with other foods, or used...

  6. 7 CFR 58.714 - Cream cheese, Neufchatel cheese.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Specifications for Dairy Plants Approved for USDA Inspection and Grading Service 1 Quality Specifications for Raw Material § 58.714 Cream cheese, Neufchatel cheese. These cheeses when mixed with other foods, or used...

  7. 7 CFR 58.714 - Cream cheese, Neufchatel cheese.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Specifications for Dairy Plants Approved for USDA Inspection and Grading Service 1 Quality Specifications for Raw Material § 58.714 Cream cheese, Neufchatel cheese. These cheeses when mixed with other foods, or used...

  8. Mercury content in low cost skin lightening cream products.

    PubMed

    Naser, J; Kirm, I

    2012-04-01

    Skin lightening creams were randomly collected from local markets in Sultanate of Oman for analysis of mercury (II) content. All the products collected were of low cost imported materials from different countries. Cream samples were digested in nitric acid and hydrogen peroxide at elevated temperature using a microwave digester. The mercury content was measured using Flow Injection Atomic Spectroscopy (FIAS)-Mercury Hydride System. Out of forty cream samples analyzed, about one fourth of the samples contained higher levels of mercury which is more than the maximum mercury content of 1 microg/g permitted by the Food and Drug Administration regulation. The mercury level in the analyzed samples is found to be in the range from 0.02 to 25.7 microg/g. Among the analyzed skin lightening cream samples half of the materials did not have any detectable mercury content.

  9. 7 CFR 58.648 - Microbiological requirements for ice cream.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Service 1 Requirements for Finished Products Bearing Usda Official Identification § 58.648 Microbiological requirements for ice cream. The finished product shall contain not more than 50,000 bacteria per gram...

  10. 7 CFR 58.648 - Microbiological requirements for ice cream.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Service 1 Requirements for Finished Products Bearing Usda Official Identification § 58.648 Microbiological requirements for ice cream. The finished product shall contain not more than 50,000 bacteria per gram...

  11. 7 CFR 58.648 - Microbiological requirements for ice cream.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Service 1 Requirements for Finished Products Bearing Usda Official Identification § 58.648 Microbiological requirements for ice cream. The finished product shall contain not more than 50,000 bacteria per gram...

  12. 7 CFR 58.648 - Microbiological requirements for ice cream.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Service 1 Requirements for Finished Products Bearing Usda Official Identification § 58.648 Microbiological requirements for ice cream. The finished product shall contain not more than 50,000 bacteria per gram...

  13. FORMULATION DEVELOPMENT OF TOPICAL CREAM LOADED WITH ANANAS COMOSUS EXTRACT: IN VIVO EVALUATION FOR CHANGES IN SKIN BARRIER FUNCTION USING BIOPHYSICAL TECHNIQUES.

    PubMed

    Arshad, Atif I; Khan, Shoaib H M; Akhtar, Naveed

    2016-01-01

    The prime objective of current investigation was to develop a topical skin care cream (w/o) loaded with Ananas comosus extract versus placebo control, and evaluated non-invasively for changes in skin barrier function i.e., epidermal hydration levels and transepidermal water loss (TEWL), on healthy human volunteers. Active cream carrying 2% extract of Ananas comosus in the internal phase of w/o emulsion was prepared while placebo contained no extract. Stability assessment of both creams was performed at various storage conditions 8, 25, 40 degrees C, 40 degrees C + 75% RH (relative humidity) and 50 degrees C. Effects on epidermal hydration and TEWL were observed by applying active cream at one side and placebo on the other side of face by 11 healthy human volunteers during 12 weeks period using Corneometer MPA5 and Tewameter MPA5. Results indicated that both creams (active and placebo) remained stable at all storage conditions. All samples manifested non-Newtonian, shear thinning behavior with increasing shear rate, whereas statistical interpretation indicated that effects of active cream were superior than placebo, as it significantly (p = 0.05) improves the epidermal hydration levels up to 56.74% and reduces TEWL up to -73.19% at the end of study period compared to baseline value. The surface evaluation of living skin (SELS) parameters SEr, SEsc, SEsm, SEw were also assessed and indicated a significant (p = 0.05) reduction. Conclusively, creams loaded with Ananas comosus extract exhibit better physicochemical stability and represent a propitious improvement in skin barrier function, used as a functional moisturizing and anti-aging ingredient in topical skincare products.

  14. Notice of Release of ZipperCream-CG, a Large-seeded, Cream-type Southernpea with a Green Cotyledon Phenotype

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The USDA has developed a high yielding, large-seeded, cream-type southernpea cultivar with a green cotyledon phenotype. The new cultivar, named ZipperCream-GC, can be harvested at the dry-pod stage of maturity without loss of the pea’s fresh green color. ZipperCream-CG was developed as a replaceme...

  15. Behavior Change Techniques Implemented in Electronic Lifestyle Activity Monitors: A Systematic Content Analysis

    PubMed Central

    Lewis, Zakkoyya H; Mayrsohn, Brian G; Rowland, Jennifer L

    2014-01-01

    Background Electronic activity monitors (such as those manufactured by Fitbit, Jawbone, and Nike) improve on standard pedometers by providing automated feedback and interactive behavior change tools via mobile device or personal computer. These monitors are commercially popular and show promise for use in public health interventions. However, little is known about the content of their feedback applications and how individual monitors may differ from one another. Objective The purpose of this study was to describe the behavior change techniques implemented in commercially available electronic activity monitors. Methods Electronic activity monitors (N=13) were systematically identified and tested by 3 trained coders for at least 1 week each. All monitors measured lifestyle physical activity and provided feedback via an app (computer or mobile). Coding was based on a hierarchical list of 93 behavior change techniques. Further coding of potentially effective techniques and adherence to theory-based recommendations were based on findings from meta-analyses and meta-regressions in the research literature. Results All monitors provided tools for self-monitoring, feedback, and environmental change by definition. The next most prevalent techniques (13 out of 13 monitors) were goal-setting and emphasizing discrepancy between current and goal behavior. Review of behavioral goals, social support, social comparison, prompts/cues, rewards, and a focus on past success were found in more than half of the systems. The monitors included a range of 5-10 of 14 total techniques identified from the research literature as potentially effective. Most of the monitors included goal-setting, self-monitoring, and feedback content that closely matched recommendations from social cognitive theory. Conclusions Electronic activity monitors contain a wide range of behavior change techniques typically used in clinical behavioral interventions. Thus, the monitors may represent a medium by which

  16. State monitoring activities related to Pfiesteria-like organisms.

    PubMed

    Magnien, R E

    2001-10-01

    In response to potential threats to human health and fish populations, six states along the east coast of the United States initiated monitoring programs related to Pfiesteria-like organisms in 1998. These actions were taken in the wake of toxic outbreaks of Pfiesteria piscicida Steidinger & Burkholder in Maryland during 1997 and previous outbreaks in North Carolina. The monitoring programs have two major purposes. The first, rapid response, is to ensure public safety by responding immediately to conditions that may indicate the presence of Pfiesteria or related organisms in a toxic state. The second, comprehensive assessment, is to provide a more complete understanding of where Pfiesteria-like organisms may become a threat, to understand what factors may stimulate their growth and toxicity, and to evaluate the impacts of these organisms upon fish and other aquatic life. In states where human health studies are being conducted, the data from both types of monitoring are used to provide information on environmental exposure. The three elements included in each monitoring program are identification of Pfiesteria-like organisms, water quality measurements, and assessments of fish health. Identification of Pfiesteria-like organisms is a particularly difficult element of the monitoring programs, as these small species cannot be definitively identified using light microscopy; newly applied molecular techniques, however, are starting to provide alternatives to traditional methods. State monitoring programs also offer many opportunities for collaborations with research initiatives targeting both environmental and human health issues related to Pfiesteria-like organisms.

  17. State monitoring activities related to Pfiesteria-like organisms.

    PubMed Central

    Magnien, R E

    2001-01-01

    In response to potential threats to human health and fish populations, six states along the east coast of the United States initiated monitoring programs related to Pfiesteria-like organisms in 1998. These actions were taken in the wake of toxic outbreaks of Pfiesteria piscicida Steidinger & Burkholder in Maryland during 1997 and previous outbreaks in North Carolina. The monitoring programs have two major purposes. The first, rapid response, is to ensure public safety by responding immediately to conditions that may indicate the presence of Pfiesteria or related organisms in a toxic state. The second, comprehensive assessment, is to provide a more complete understanding of where Pfiesteria-like organisms may become a threat, to understand what factors may stimulate their growth and toxicity, and to evaluate the impacts of these organisms upon fish and other aquatic life. In states where human health studies are being conducted, the data from both types of monitoring are used to provide information on environmental exposure. The three elements included in each monitoring program are identification of Pfiesteria-like organisms, water quality measurements, and assessments of fish health. Identification of Pfiesteria-like organisms is a particularly difficult element of the monitoring programs, as these small species cannot be definitively identified using light microscopy; newly applied molecular techniques, however, are starting to provide alternatives to traditional methods. State monitoring programs also offer many opportunities for collaborations with research initiatives targeting both environmental and human health issues related to Pfiesteria-like organisms. PMID:11677180

  18. GRID based Thermal Images Processing for volcanic activity monitoring

    NASA Astrophysics Data System (ADS)

    Mangiagli, S.; Coco, S.; Drago, L.; Laudani, A.,; Lodato, L.; Pollicino, G.; Torrisi, O.

    2009-04-01

    Since 2001, the Catania Section of the National Institute of Geophysics and Volcanology (INGV) has been running the video stations recording the volcanic activity of Mount Etna, Stromboli and the Fossa Crater of Vulcano island. The video signals of 11 video cameras (seven operating in the visible band and four in infrared) are sent in real time to INGV Control Centre where they are visualized on monitors and archived on a dedicated NAS storage. The video surveillance of the Sicilian volcanoes, situated near to densely populated areas, helps the volcanologists providing the Civil Protection authorities with updates in real time on the on-going volcanic activity. In particular, five video cameras are operating on Mt. Etna and they record the volcano from the south and east sides 24 hours a day. During emergencies, mobile video stations may also be used to better film the most important phases of the activity. Single shots are published on the Catania Section intranet and internet websites. On June 2006 a A 40 thermal camera was installed in Vulcano La Fossa Crater. The location was in the internal and opposite crater flank (S1), 400 m distant from the fumarole field. The first two-year of data on temperature distribution frequency were recorded with this new methodology of acquisition, and automatically elaborated by software at INGV Catania Section. In fact a dedicated software developed in IDL, denominated Volcano Thermo Analysis (VTA), was appositely developed in order to extract a set of important features, able to characterize with a good approssimation the volcanic activity. In particular the program first load and opportunely convert the thermal images, then according to the Region Of Interest (ROI) and the temperature ranges defined by the user provide to automatic spatial and statistic analysis. In addition the VTA is able to analysis all the temporal series of images available in order to achieve the time-event analysis and the dynamic of the volcanic

  19. Comparative characterisation of green tea and black tea cream: physicochemical and phytochemical nature.

    PubMed

    Lin, Xiaorong; Chen, Zhongzheng; Zhang, Yuanyuan; Luo, Wei; Tang, Hao; Deng, Baibiao; Deng, Jian; Li, Bin

    2015-04-15

    Tea cream is prevalent in various types of tea, yet a comparison of the mechanism of creaming in different teas remains uncertain. Here, we compared physicochemical characteristics, phytochemical composition, and simulated digestive profiles of green tea and black tea cream, looking to exploit their concentration and structure based mechanisms and in vitro bioaccessibility. Green tea cream particles were roughly one order of magnitude larger than those of black tea in size. Moreover, creaming concentrations of catechins, proteins and methylxanthines of green tea were dramatically higher than black tea. As major creaming components, gallated catechins, theaflavins, thearubigins, theabrownines, proteins and methylxanthines also exhibited high creaming affinities. Green tea cream particles, which were completely destroyed by simulated digestion, had few impacts on digestive recoveries of catechins and methylxanthines. In comparison, black tea cream particles were more stable under mimicking digestion, and clarification remarkably decreased the in vitro bioaccessibility of catechins and methylxanthines.

  20. Evaluating sago as a functional ingredient in dietetic mango ice cream.

    PubMed

    Patel, Ashish S; Jana, Atanu H; Aparnathi, Kishore D; Pinto, Suneeta V

    2010-10-01

    A low fat mango ice cream (2.4% milk fat) was prepared in a mechanized 'ice and salt' type freezer using powdered sago at 2.5% as a natural bulking agent along with sodium alginate at 0.025% as adjunct. The low fat mango ice cream was compared with control mango ice cream having 10% milk fat and 0.15% sodium alginate as stabilizer. Both control as well as experimental ice creams contained 20% mango pulp solids. To impart richness to low fat mango ice cream, flavour enhancers like Cream Plus and Butter Buds were used at levels of 0.2% and 0.05%, respectively. The dietetic low fat ice creams compared well in sensory colour and appearance, flavour, body and texture, and melting quality to that of control ice cream. Incorporation of 2.5% powdered sago and 0.2% Cream Plus as flavour adjunct is recommended in the manufacture of 'low-fat' mango ice cream. The energy values for control and dietetic mango ice cream was 202.8 and 142.9 kcal/100 g, respectively, which represents about 30% reduction in calorie. The cost of ice cream per liter was Rs 39.9, Rs 37.6 and Rs 49.7 for experimental ice creams containing Cream Plus and Butter Bud, and control, respectively.

  1. Evaluation of a nonsteroidal topical cream in a guinea pig model of Malassezia furfur infection.

    PubMed

    Nalamothu, Vijendra; O'Leary, Ann L; Kandavilli, Sateesh; Fraser, Joanne; Pandya, Vishvabhavan

    2009-01-01

    Malassezia furfur is an important causal factor for seborrheic dermatitis, and topical antifungal therapy is an effective treatment approach. This study assessed the antifungal activity of Promiseb Topical Cream (Promius Pharma, LLC, Bridgewater, NJ), a novel nonsteroidal prescription medical device cream, in the M furfur-infected skin model for guinea pigs. Guinea pigs (N = 28) were divided into 4 groups and infected with M furfur for 7 days. On day 8, the first group of animals was sacrificed. The scrapings of inoculation site on each animal were tested for the presence of the organism, and the skin was excised for quantitation of M furfur. The second group was left untreated. The remaining 2 groups were treated with one of the test agents (Promiseb) and the positive control product (ciclopirox olamine cream, 0.77%; Loprox, Medicis, Scottsdale, AZ) each once daily for 3 days. At the end of treatment, animals were sacrificed and analyzed similarly to the first group. M furfur was recovered from all animals in the first group. Visual signs of infection, such as erythema and edema, were not observed in the infected animals at the end of the study. In the animals treated for 3 days with the test agents, the M furfur counts were reduced to below the limit of quantitation. Both test agents were equally effective in substantially reducing the density of M furfur compared with the untreated control.

  2. Monitoring seismic wave speed by an active seismic source

    NASA Astrophysics Data System (ADS)

    Yokoyama, K.; Kawakata, H.; Doi, I.; Okubo, M.; Saiga, A.

    2012-12-01

    Decreases in elastic wave speed around cracked zones prior to faulting in rock fracture experiments have been reported (e.g., Yukutake, 1989; Yoshimitsu et al., 2009). These decreases in wave speed have been considered to be associated with crack and fault growth based on non-destructive observation using X-ray CT scan (Kawakata et al., 1999). Meanwhile, there were some reports on the decreases in seismic wave speed along paths that cross the hypocentral area in periods including some large earthquakes. Uchida et al. (2002) analyzed seismic waveform with explosive sources before and after the 1998 northern Iwate prefecture earthquake, and they showed that the decrease in seismic wave speed approximately 0.1-0.9 % by the earthquake occurrence. Justin et al. (2007) reported the reduction in seismic wave speed accompanied with the 2003 Tokachi oki earthquake around the rupture area by using the four repeating earthquakes that occurred before and after the 2003 Tokachi oki earthquake. However, seismograms of explosive sources or repeating earthquakes are hard to be frequently recorded, which makes the time intervals of estimated seismic wave speed be too long to distinguish preseismic changes from coseismic and post seismic changes. In order to monitor crustal structures and detecting the variation of rock properties in the crust, a kind of active seismic source systems ACROSS (Accurately Controlled Routinely Operated Signal System) has been developed(e.g., Kunitomo and Kumazawa, 2004). We used the controlled seismic source ACROSS, which installed at the Tono mine, Gifu prefecture, central Japan and has been routinely operated by Tono Geoscience center of JAEA (Japan Atomic Energy Agency), automatically. Frequency modulated seismic waves are continuously radiated from approximately 10-20 Hz by eccentric rotation of the source. In order to investigate the stability of ACROSS signals, we used seismograms recorded at the 110m depth of Shobasama observing site, which is

  3. Embedded Ultrasonic Transducers for Active and Passive Concrete Monitoring

    PubMed Central

    Niederleithinger, Ernst; Wolf, Julia; Mielentz, Frank; Wiggenhauser, Herbert; Pirskawetz, Stephan

    2015-01-01

    Recently developed new transducers for ultrasonic transmission, which can be embedded right into concrete, are now used for non-destructive permanent monitoring of concrete. They can be installed during construction or thereafter. Large volumes of concrete can be monitored for changes of material properties by a limited number of transducers. The transducer design, the main properties as well as installation procedures are presented. It is shown that compressional waves with a central frequency of 62 kHz are mainly generated around the transducer’s axis. The transducer can be used as a transmitter or receiver. Application examples demonstrate that the transducers can be used to monitor concrete conditions parameters (stress, temperature, …) as well as damages in an early state or the detection of acoustic events (e.g., crack opening). Besides application in civil engineering our setups can also be used for model studies in geosciences. PMID:25923928

  4. Pentadecapeptide BPC 157 cream improves burn-wound healing and attenuates burn-gastric lesions in mice.

    PubMed

    Mikus, D; Sikiric, P; Seiwerth, S; Petricevic, A; Aralica, G; Druzijancic, N; Rucman, R; Petek, M; Pigac, B; Perovic, D; Kolombo, M; Kokic, N; Mikus, S; Duplancic, B; Fattorini, I; Turkovic, B; Rotkvic, I; Mise, S; Prkacin, I; Konjevoda, P; Stambuk, N; Anic, T

    2001-12-01

    -treated mice completely reversed the otherwise poor re-epithelization ratio noted in the untreated control or mice treated with vehicle only. Tensiometry investigation showed an increased breaking strength and relative elongation of burned skin, while water content in burned skin decreased. This was, however, not the case with the vehicle or silver sulfadiazine. Relative to the control values, in silver sulfadiazine cream-treated mice, only collagen fiber formation was increased, in addition to a decreased inflammatory cell number. Relative to control values, BPC 157 given i.p. decreased the number of inflammatory cells, lowered water content in burned skin, and raised breaking strength and relative elongation of burned skin during tensiometry. Through the experimental period, gastric lesions were continuously noted in all thermally injured mice left without local medication and they were consistently attenuated only by BPC 157 treatments: either given i.p. (at either dose), or given locally (at either concentration). Other treatments (i.e. local treatment with silver sulfadiazine cream or neutral cream in mice subjected for 5 s to direct flame), led to only poor, if any attenuation. This stable gastric pentadecapeptide appears to be active and gives a stimulation to burn healing at the defect site. The agent may act by causing an upregulation of the growth factors, as well as influencing other local factors.

  5. When a Step Is Not a Step! Specificity Analysis of Five Physical Activity Monitors

    PubMed Central

    O’Connell, Sandra; ÓLaighin, Gearóid

    2017-01-01

    Introduction Physical activity is an essential aspect of a healthy lifestyle for both physical and mental health states. As step count is one of the most utilized measures for quantifying physical activity it is important that activity-monitoring devices be both sensitive and specific in recording actual steps taken and disregard non-stepping body movements. The objective of this study was to assess the specificity of five activity monitors during a variety of prescribed non-stepping activities. Methods Participants wore five activity monitors simultaneously for a variety of prescribed activities including deskwork, taking an elevator, taking a bus journey, automobile driving, washing and drying dishes; functional reaching task; indoor cycling; outdoor cycling; and indoor rowing. Each task was carried out for either a specific duration of time or over a specific distance. Activity monitors tested were the ActivPAL micro™, NL-2000™ pedometer, Withings Smart Activity Monitor Tracker (Pulse O2)™, Fitbit One™ and Jawbone UP™. Participants were video-recorded while carrying out the prescribed activities and the false positive step count registered on each activity monitor was obtained and compared to the video. Results All activity monitors registered a significant number of false positive steps per minute during one or more of the prescribed activities. The Withings™ activity performed best, registering a significant number of false positive steps per minute during the outdoor cycling activity only (P = 0.025). The Jawbone™ registered a significant number of false positive steps during the functional reaching task and while washing and drying dishes, which involved arm and hand movement (P < 0.01 for both). The ActivPAL™ registered a significant number of false positive steps during the cycling exercises (P < 0.001 for both). Conclusion As a number of false positive steps were registered on the activity monitors during the non-stepping activities, the

  6. Relationship between balance and physical activity measured by an activity monitor in elderly COPD patients

    PubMed Central

    Iwakura, Masahiro; Okura, Kazuki; Shibata, Kazuyuki; Kawagoshi, Atsuyoshi; Sugawara, Keiyu; Takahashi, Hitomi; Shioya, Takanobu

    2016-01-01

    Background Little is known regarding the relationship between balance impairments and physical activity in COPD. There has been no study investigating the relationship between balance and objectively measured physical activity. Here we investigated the association between balance and physical activity measured by an activity monitor in elderly COPD patients. Materials and methods Twenty-two outpatients with COPD (mean age, 72±7 years; forced expiratory volume in 1 second, 53%±21% predicted) and 13 age-matched healthy control subjects (mean age, 72±6 years) participated in the study. We assessed all 35 subjects’ balance (one-leg standing test [OLST] times, Short Physical Performance Battery total scores, standing balance test scores, 4 m gait speed, and five-times sit-to-stand test [5STST]) and physical activity (daily steps and time spent in moderate-to-vigorous physical activity per day [MV-PA]). Possible confounders were assessed in the COPD group. The between-group differences in balance test scores and physical activity were analyzed. A correlation analysis and multivariate regression analysis were conducted in the COPD group. Results The COPD patients exhibited significant reductions in OLST times (P=0.033), Short Physical Performance Battery scores (P=0.013), 4 m gait speed (P<0.001), five-times sit-to-stand times (P=0.002), daily steps (P=0.003), and MV-PA (P=0.022) compared to the controls; the exception was the standing balance test scores. The correlation and multivariate regression analyses revealed significant independent associations between OLST times and daily steps (P<0.001) and between OLST times and MV-PA (P=0.014) in the COPD group after adjusting for possible confounding factors. Conclusion Impairments in balance and reductions in physical activity were observed in the COPD group. Deficits in balance are independently associated with physical inactivity. PMID:27445470

  7. Monitoring

    SciTech Connect

    Orr, Christopher Henry; Luff, Craig Janson; Dockray, Thomas; Macarthur, Duncan Whittemore

    2004-11-23

    The invention provides apparatus and methods which facilitate movement of an instrument relative to an item or location being monitored and/or the item or location relative to the instrument, whilst successfully excluding extraneous ions from the detection location. Thus, ions generated by emissions from the item or location can successfully be monitored during movement. The technique employs sealing to exclude such ions, for instance, through an electro-field which attracts and discharges the ions prior to their entering the detecting location and/or using a magnetic field configured to repel the ions away from the detecting location.

  8. Effect of Calendula officinalis cream on achilles tendon healing.

    PubMed

    Aro, A A; Perez, M O; Vieira, C P; Esquisatto, M A M; Rodrigues, R A F; Gomes, L; Pimentel, E R

    2015-02-01

    In recent years, the scientific community has undertaken research on plant extracts, searching for compounds with pharmacological activities that can be used in diverse fields of medicine. Calendula officinalis L. is known to have antioxidant, anti-inflammatory, antibacterial, and wound healing properties when used to treat skin burns. Therefore, the purpose of this study was to analyze the effects of C. officinalis on the initial phase of Achilles tendon healing. Wistar rats were separated in three groups: Calendula (Cal)-rats with a transected tendon were treated with topical applications of C. officinalis cream and then euthanized 7 days after injury; Control (C)-rats were treated with only vehicle after transection; and Normal (N)-rats without tenotomy. Higher concentrations of hydroxyproline (an indicator of total collagen) and non-collagenous proteins were observed in the Cal group in relation to the C group. Zymography showed no difference in the amount of the isoforms of metalloproteinase-2 and of metalloproteinase-9, between C and Cal groups. Polarization microscopy images analysis showed that the Cal group presented a slightly higher birefringence compared with the C group. In sections of tendons stained with toluidine blue, the transected groups presented higher metachromasy as compared with the N group. Immunocytochemistry analysis for chondroitin-6-sulfate showed no difference between the C and Cal groups. In conclusion, the topical application of C. officinalis after tendon transection increases the concentrations of collagen and non-collagenous proteins, as well as the collagen organization in the initial phase of healing.

  9. Monitoring of acoustic emission activity using thin wafer piezoelectric sensors

    NASA Astrophysics Data System (ADS)

    Trujillo, Blaine; Zagrai, Andrei; Meisner, Daniel; Momeni, Sepand

    2014-03-01

    Acoustic emission (AE) is a well-known technique for monitoring onset and propagation of material damage. The technique has demonstrated utility in assessment of metallic and composite materials in applications ranging from civil structures to aerospace vehicles. While over the course of few decades AE hardware has changed dramatically with the sensors experiencing little changes. A traditional acoustic emission sensor solution utilizes a thickness resonance of the internal piezoelectric element which, coupled with internal amplification circuit, results in relatively large sensor footprint. Thin wafer piezoelectric sensors are small and unobtrusive, but they have seen limited AE applications due to low signal-to-noise ratio and other operation difficulties. In this contribution, issues and possible solutions pertaining to the utility of thin wafer piezoelectrics as AE sensors are discussed. Results of AE monitoring of fatigue damage using thin wafer piezoelectric and conventional AE sensors are presented.

  10. Energy monitoring based on human activity in the workplace

    NASA Astrophysics Data System (ADS)

    Mustafa, N. H.; Husain, M. N.; Abd Aziz, M. Z. A.; Othman, M. A.; Malek, F.

    2014-04-01

    Human behavior is the most important factor in order to manage energy usage. Nowadays, smart house technology offers a better quality of life by introducing automated appliance control and assistive services. However, human behaviors will contribute to the efficiency of the system. This paper will focus on monitoring efficiency based on duration time in office hours around 8am until 5pm which depend on human behavior atb the workplace. Then, the correlation coefficient method is used to show the relation between energy consumption and energy saving based on the total hours of time energy spent. In future, the percentages of energy monitoring system usage will be increase to manage energy in efficient ways based on human behaviours. This scenario will lead to the positive impact in order to achieve the energy saving in the building and support the green environment.

  11. A mobile system for active otpical pollution monitoring

    NASA Technical Reports Server (NTRS)

    Sunesson, A.; Edner, H.; Svanberg, S.; Uneus, L.; Wendt, W.; Fredriksson, K.

    1986-01-01

    The remote monitoring of atmospheric pollutants can now be performed in several ways. Laser radar techniques have proven their ability to reveal the spatial distribution of different species or particles. Classical optical techniques can also be used, but yield the average concentration over a given path and hence no range resolution. One such technique is Differential Optical Absorption Spectroscopy, DOAS. Such schemes can be used to monitor paths that a preliminary lidar investigation has shown to be of interest. Having previously had access to a mobile lidar system, a new system has been completed. The construction builds on experience from using the other system and it is meant to be more of a mobile optical laboratory than just a lidar system. A complete system description is given along with some preliminary usage. Future uses are contemplated.

  12. Cable condition monitoring research activities at Sandia National Laboratories

    SciTech Connect

    Jacobus, M.J.; Zigler, G.L.; Bustard, L.D.

    1988-01-01

    Sandia National Laboratories is currently conducting long-term aging research on representative samples of nuclear power plant cables. The objectives of the program are to determine the suitability of these cables for extended life (beyond 40 year design basis) and to assess various cable condition monitoring techniques for predicting remaining cable life. The cables are being aged for long times at relatively mild exposure conditions with various condition monitoring techniques to be employed during the aging process. Following the aging process, the cables will be exposed to a sequential accident profile consisting of high dose rate irradiation followed by a simulated design basis loss-of-coolant accident (LOCA) steam exposure. 12 refs., 1 fig., 1 tab.

  13. Active subjects of passive monitoring: responses to a passive monitoring system in low-income independent living

    PubMed Central

    BERRIDGE, CLARA

    2016-01-01

    Passive monitoring technology is beginning to be reimbursed by third-party payers in the United States of America. Given the low voluntary uptake of these technologies on the market, it is important to understand the concerns and perspectives of users, former users and non-users. In this paper, the range of ways older adults relate to passive monitoring in low-income independent-living residences is presented. This includes experiences of adoption, non-adoption, discontinuation and creative ‘misuse’. The analysis of interviews reveals three key insights. First, assumptions built into the technology about how older adults live present a problem for many users who experience unwanted disruptions and threats to their behavioural autonomy. Second, resident response is varied and challenges the dominant image of residents as passive subjects of a passive monitoring system. Third, the priorities of older adults (e.g. safety, autonomy, privacy, control, contact) are more diverse and multi-faceted than those of the housing organisation staff and family members (e.g. safety, efficiency) who drive the passive monitoring intervention. The tension between needs, desires and the daily lives of older adults and the technological solutions offered to them is made visible by their active responses, including resistance to them. This exposes the active and meaningful qualities of older adults’ decisions and practices. PMID:28239211

  14. Active subjects of passive monitoring: responses to a passive monitoring system in low-income independent living.

    PubMed

    Berridge, Clara

    2017-03-01

    Passive monitoring technology is beginning to be reimbursed by third-party payers in the United States of America. Given the low voluntary uptake of these technologies on the market, it is important to understand the concerns and perspectives of users, former users and non-users. In this paper, the range of ways older adults relate to passive monitoring in low-income independent-living residences is presented. This includes experiences of adoption, non-adoption, discontinuation and creative 'misuse'. The analysis of interviews reveals three key insights. First, assumptions built into the technology about how older adults live present a problem for many users who experience unwanted disruptions and threats to their behavioural autonomy. Second, resident response is varied and challenges the dominant image of residents as passive subjects of a passive monitoring system. Third, the priorities of older adults (e.g. safety, autonomy, privacy, control, contact) are more diverse and multi-faceted than those of the housing organisation staff and family members (e.g. safety, efficiency) who drive the passive monitoring intervention. The tension between needs, desires and the daily lives of older adults and the technological solutions offered to them is made visible by their active responses, including resistance to them. This exposes the active and meaningful qualities of older adults' decisions and practices.

  15. FRET-Based Optical Assay for Monitoring Riboswitch Activation

    DTIC Science & Technology

    2009-04-09

    including small organic molecules, peptides, and aminoglycosides among others. 10 The advantage of such engineered riboswitches is that they offer a way...Laboratory, Dayton, OH. ‡ USAMRMC, Fort Detrick, MD. Biomacromolecules 2009, 10 , 1055–1060 1055 10.1021/bm801117f CCC: $40.75  2009 American Chemical...SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10 . SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION

  16. Activity Monitors Help Users Get Optimum Sun Exposure

    NASA Technical Reports Server (NTRS)

    2015-01-01

    Goddard scientist Shahid Aslam was investigating alternative methods for measuring extreme ultraviolet radiation on the Solar Dynamics Observatory when he hit upon semiconductors that measured wavelengths pertinent to human health. As a result, he and a partner established College Park, Maryland-based Sensor Sensor LLC and developed UVA+B SunFriend, a wrist monitor that lets people know when they've received their optimal amounts of sunlight for the day.

  17. Selection of fragrance for cosmetic cream containing olive oil.

    PubMed

    Parente, María Emma; Gámbaro, Adriana; Boinbaser, Lucía; Roascio, Antonella

    2014-01-01

    Perceptions of essences for potential use in the development of a line of cosmetic emulsions containing olive oil were studied. Six cream samples prepared with six essences selected in a preliminary study were evaluated for overall liking and intention to purchase by a 63-women sample. A check-all-that-apply (CATA) question consisting of 32 terms was used to gather information about consumer perceptions of fragrance, affective associations, effects on the skin, price, target market, zones of application, and occasions of use. Hierarchical cluster analysis led to the identification of two consumer clusters with different frequency of use of face creams. The two clusters assigned different overall liking scores to the samples and used the CATA terms differently to describe them. A fragrance with jasmine as its principal note was selected for further development of cosmetic creams, as it was awarded the highest overall liking scores by respondents of the two clusters, and was significantly associated with cosmetic features including nourishing, moisturizing, softening, with a delicious and mild smell, and with a natural image, as well as being considered suitable for face and body creams. The use of CATA questions enabled the rapid identification of attributes associated by respondents with a cosmetic cream's fragrance, in addition to contributing relevant information for the definition of marketing and communication strategies.

  18. 30 CFR 280.29 - Will MMS monitor the environmental effects of my activity?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Obligations Under This Part Environmental Issues § 280.29 Will MMS monitor the environmental effects of my... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Will MMS monitor the environmental effects of my activity? 280.29 Section 280.29 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF...

  19. Active monitoring as cognitive control of grinders design

    NASA Astrophysics Data System (ADS)

    Flizikowski, Jozef B.; Mrozinski, Adam; Tomporowski, Andrzej

    2017-03-01

    A general monitoring methodology applicable to plastics recyclates grinding processes development for energy engineering, has been presented in this work. The method includes two beings: mathematical aiding an invention and working of a novelty. The common set is composed of characteristics, structure, relationships of knowledge about states and transformations, effectiveness and progress of the devices and machinery engineering, e.g. breaking up in the energy-materials recycling process. This innovations theory is identified by the valuation, estimation, testing and creative archiving the elaborated character and structure of the invention and grinders construction development.

  20. Effect of an antioxydant cream versus placebo in patients with vitiligo in association with excimer laser. A pilot randomized, investigator-blinded, and half-side comparison trial.

    PubMed

    Leone, G; Paro Vidolin, A

    2015-08-01

    The aim of this study was to evaluate the combined effect of excimer laser and a topical antioxidant in the treatment for vitiligo. The study was conducted in a single blinded design on 10 vitiligo patients with symmetrical vitiligo lesions treated with the active antioxidant or a placebo that were irradiated with an excimer laser. Results have shown that the lesions treated with the active cream achieved earlier regimentation compared to the placebo. The use of a cream containing antioxidants may improve the results of excimer laser treatment in patients with vitiligo.

  1. Physical Activity Monitoring in Extremely Obese Adolescents from the Teen-LABS Study

    PubMed Central

    Jeffries, Renee M.; Inge, Thomas H.; Jenkins, Todd M; King, Wendy; Oruc, Vedran; Douglas, Andrew D.

    2016-01-01

    Background The accuracy of physical activity (PA) monitors to discriminate between PA, sedentary behavior, and non-wear in extremely obese (EO) adolescents is unknown. Methods Twenty-five subjects (9 male/16 female; age=16.5±2.0 y; BMI=51±8 kg/m2) wore three activity monitors (StepWatch [SAM], Actical [AC], Actiheart [AH]) during a 400 meter walk test (400MWT), two standardized PA bouts of varying duration, and one sedentary bout. Results For the 400MWT, percent error between observed and monitor recorded steps was 5.5±7.1% and 82.1±38.6% for the SAM and AC steps, respectively (observed vs. SAM steps: −17.2±22.2 steps; observed vs. AC steps: −264.5±124.8 steps). All activity monitors were able to differentiate between PA and sedentary bouts but only SAM steps and AH heart rate were significantly different between sedentary behavior and non-wear (p<0.001). For all monitors, sedentary behavior was characterized by bouts of zero steps/counts punctuated by intermittent activity steps/counts; non-wear was represented almost exclusively by zero steps/counts. Conclusion Of all monitors tested, the SAM was most accurate in terms of counting steps and differentiating levels of PA, and thus, most appropriate for EO adolescents. The ability to accurately characterize PA intensity in EO adolescents critically depends on activity monitor selection. PMID:25205688

  2. Effects of emulsifying components in the continuous phase of cream on the stability of fat globules and the physical properties of whipped cream.

    PubMed

    Ihara, K; Hirota, M; Akitsu, T; Urakawa, K; Abe, T; Sumi, M; Okawa, T; Fujii, T

    2015-05-01

    The emulsifying components in cream are very important in controlling the physical characteristics of whipped cream. The effects of those components on the stability of fat globules and the physical characteristics of whipped cream were investigated. A low-molecular-weight emulsifier, and protein ingredients such as sodium caseinate and a casein partial hydrolysate (casein peptides), were used as emulsifying components in this investigation. The viscosity of deaerated whipped cream (called the serum viscosity) was measured to evaluate the degree of fat-globule aggregation. Furthermore, the shape-retention ability, which is the degree of reduction in the firmness of whipped cream between immediately after whipping and after 1d of refrigeration, was explored. The addition of the low-molecular-weight emulsifier in the continuous phase of dairy cream, which does not contain added low-molecular-weight emulsifiers, increased the stability of the fat globules and reduced the shape-retention ability of the whipped cream. The addition of protein ingredients (sodium caseinate and casein peptides) to the continuous phase of dairy cream had little effect. However, the addition of casein peptide in the continuous phase of dairy cream together with the low-molecular-weight emulsifier reduced the effect of the low-molecular-weight emulsifier on the stabilization of fat globules and the shape-retention ability of the whipped cream. The addition of casein peptide did not recover the serum viscosity; thus, other mechanisms might underlie this phenomenon.

  3. Effect of γ-radiation on ointment cold cream

    NASA Astrophysics Data System (ADS)

    Qu, L. B.; Zhou, Z. M.; Liu, J. X.; Chen, X. L.

    1993-10-01

    In this paper, Co-60γ ray was used to irradiate the ointment cold cream at room temperature (25°C). We also used FTIR, GC and thin film chromatogram to analyse various irradiated samples. It was found that the ointment cold cream can be irradiated at dose of 5-35 kGy and at dose rate from 0.2 to 0.6 kGy/h at room temperature (25°C) without evident decomposition. At dose of 5-15 kGy, the number of bacteria can be reduced to hygienic standard value. The radiation sterilization is a safe method for killing the bacteria in the ointment cold cream.

  4. Mercury toxicity due to use of a cosmetic cream.

    PubMed

    McRill, C; Boyer, L V; Flood, T J; Ortega, L

    2000-01-01

    The Arizona Department of Health Services performed an investigation to determine the health effects associated with the use of a mercury-containing beauty cream. A urine test for mercury was offered to cream users who contacted the Arizona Department of Health Services. Those with urine mercury levels > 20 micrograms/L were offered clinical evaluation. Eighty-nine urine specimens were submitted for testing. Of these, 66 showed an elevated urine mercury level (> 20 micrograms/L), and 55 people were evaluated in clinic. There were no major abnormalities found through physical examination or laboratory testing. Urine mercury levels declined from an initial mean of 170 micrograms/L to 32 micrograms/L at the final test (mean, 139 days later). The high urine mercury levels indicate that the use of this cosmetic cream constitutes a significant exposure. Neuropsychiatric symptoms were frequently reported, but few objective signs were noted.

  5. Testing the reliability of ice-cream cone model

    NASA Astrophysics Data System (ADS)

    Pan, Zonghao; Shen, Chenglong; Wang, Chuanbing; Liu, Kai; Xue, Xianghui; Wang, Yuming; Wang, Shui

    2015-04-01

    Coronal Mass Ejections (CME)'s properties are important to not only the physical scene itself but space-weather prediction. Several models (such as cone model, GCS model, and so on) have been raised to get rid of the projection effects within the properties observed by spacecraft. According to SOHO/ LASCO observations, we obtain the 'real' 3D parameters of all the FFHCMEs (front-side full halo Coronal Mass Ejections) within the 24th solar cycle till July 2012, by the ice-cream cone model. Considering that the method to obtain 3D parameters from the CME observations by multi-satellite and multi-angle has higher accuracy, we use the GCS model to obtain the real propagation parameters of these CMEs in 3D space and compare the results with which by ice-cream cone model. Then we could discuss the reliability of the ice-cream cone model.

  6. An ice-cream cone model for coronal mass ejections

    NASA Astrophysics Data System (ADS)

    Xue, X. H.; Wang, C. B.; Dou, X. K.

    2005-08-01

    In this study, we use an ice-cream cone model to analyze the geometrical and kinematical properties of the coronal mass ejections (CMEs). Assuming that in the early phase CMEs propagate with near-constant speed and angular width, some useful properties of CMEs, namely the radial speed (v), the angular width (α), and the location at the heliosphere, can be obtained considering the geometrical shapes of a CME as an ice-cream cone. This model is improved by (1) using an ice-cream cone to show the near real configuration of a CME, (2) determining the radial speed via fitting the projected speeds calculated from the height-time relation in different azimuthal angles, (3) not only applying to halo CMEs but also applying to nonhalo CMEs.

  7. Monitoring Activity of Taking Medicine by Incorporating RFID and Video Analysis

    PubMed Central

    Hasanuzzaman, Faiz M.; Yang, Xiaodong; Tian, YingLi; Liu, Qingshan; Capezuti, Elizabeth

    2013-01-01

    In this paper, we present a new framework to monitor medication intake for elderly individuals by incorporating a video camera and Radio Frequency Identification (RFID) sensors. The proposed framework can provide a key function for monitoring activities of daily living (ADLs) of elderly people at their own home. In an assistive environment, RFID tags are applied on medicine bottles located in a medicine cabinet so that each medicine bottle will have a unique ID. The description of the medicine data for each tag is manually input to a database. RFID readers will detect if any of these bottles are taken away from the medicine cabinet and identify the tag attached on the medicine bottle. A video camera is installed to continue monitoring the activity of taking medicine by integrating face detection and tracking, mouth detection, background subtraction, and activity detection. The preliminary results demonstrate that 100% detection accuracy for identifying medicine bottles and promising results for monitoring activity of taking medicine. PMID:23914344

  8. Active Ground Optical Remote Sensing for Improved Monitoring of Seedling Stress in Nurseries

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Active ground optical remote sensing (AGORS) devices mounted on overhead irrigation booms could help to improve seedling quality by autonomously monitoring seedling stress. In contrast to traditionally used passive optical sensors, AGORS devices operate independently of ambient light conditions and ...

  9. Nanosensor system for monitoring brain activity and drowsiness

    NASA Astrophysics Data System (ADS)

    Ramasamy, Mouli; Varadan, Vijay K.; Harbaugh, Robert

    2015-04-01

    Detection of drowsiness in drivers to avoid on-road collisions and accidents is one of the most important applications that can be implemented to avert loss of life and property caused by accidents. A statistical report indicates that drowsy driving is equally harmful as driving under influence of alcohol. This report also indicates that drowsy driving is the third most influencing factor for accidents and 30% of the commercial vehicle accidents are caused because of drowsy driving. With a motivation to avoid accidents caused by drowsy driving, this paper proposes a technique of correlating EEG and EOG signals to detect drowsiness. Feature extracts of EEG and blink variability from EOG is correlated to detect the sleepiness/drowsiness of a driver. Moreover, to implement a more pragmatic approach towards continuous monitoring, a wireless real time monitoring approach has been incorporated using textile based nanosensors. Thereby, acquired bio potential signals are transmitted through GSM communication module to the receiver continuously. In addition to this, all the incorporated electronics are equipped in a flexible headband which can be worn by the driver. With this flexible headband approach, any intrusiveness that may be experienced by other cumbersome hardware is effectively mitigated. With the continuous transmission of data from the head band, the signals are processed on the receiver side to determine the condition of the driver. Early warning of driver's drowsiness will be displayed in the dashboard of the vehicle as well as alertness voice and sound alarm will be sent via the vehicle radio.

  10. 7 CFR 58.318 - Butter, frozen or plastic cream melting machines.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Butter, frozen or plastic cream melting machines. 58... Service 1 Equipment and Utensils § 58.318 Butter, frozen or plastic cream melting machines. Shavers, shredders or melting machines used for rapid melting of butter, frozen or plastic cream shall be...

  11. 7 CFR 58.318 - Butter, frozen or plastic cream melting machines.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Butter, frozen or plastic cream melting machines. 58... Service 1 Equipment and Utensils § 58.318 Butter, frozen or plastic cream melting machines. Shavers, shredders or melting machines used for rapid melting of butter, frozen or plastic cream shall be...

  12. 7 CFR 58.318 - Butter, frozen or plastic cream melting machines.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Butter, frozen or plastic cream melting machines. 58... Service 1 Equipment and Utensils § 58.318 Butter, frozen or plastic cream melting machines. Shavers, shredders or melting machines used for rapid melting of butter, frozen or plastic cream shall be...

  13. 7 CFR 58.318 - Butter, frozen or plastic cream melting machines.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Butter, frozen or plastic cream melting machines. 58... Service 1 Equipment and Utensils § 58.318 Butter, frozen or plastic cream melting machines. Shavers, shredders or melting machines used for rapid melting of butter, frozen or plastic cream shall be...

  14. 21 CFR 131.25 - Whipped cream products containing flavoring or sweetening.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Whipped cream products containing flavoring or... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION MILK AND CREAM General Provisions § 131.25 Whipped cream products containing flavoring or sweetening. The unqualified name “whipped cream” should not be applied...

  15. 7 CFR 58.318 - Butter, frozen or plastic cream melting machines.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Butter, frozen or plastic cream melting machines. 58... Service 1 Equipment and Utensils § 58.318 Butter, frozen or plastic cream melting machines. Shavers, shredders or melting machines used for rapid melting of butter, frozen or plastic cream shall be...

  16. 21 CFR 1210.26 - Permits for raw milk or cream.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Permits for raw milk or cream. 1210.26 Section... FEDERAL IMPORT MILK ACT Permit Control § 1210.26 Permits for raw milk or cream. Except as provided in § 1210.27, permits to ship or transport raw milk or cream into the United States will be granted...

  17. [Discussing of influence mechanism of Chinese herbal monomer on physical stability of cream].

    PubMed

    Yin, Hui-Fu; Nie, He-Yun; Wang, Sen; Zhu, Wei-Feng; Li, Rong-Miao

    2014-10-01

    This study left flavonoids and alkaloids Chinese herbal monomer with common parent nucleus as cream base carriages drug respectively, cream base were prepared with stable span 60-tween 80 emulsification system. The near-infrared stability analysis technology was performed to quantitatively characterize the physical stability of cream. Base on the theory of gel network structure, theory of emulsification, theory of solubility parameter and theory of double layer, the influence mechanism of Chinese herbal monomer on physical stability of cream was discussed. The results showed that tetrahydropalmatine, matrine and naringenin had similar solubility parameter value with cream base material, creams prepared with those Chinese herbal monomer have higher Zeta potential value and stronger physical stability, and that those creams had similar microstructure information with cream base. However, a larger solubility parameter difference exists between baicalin, baicalein, berberine, palmatine and cream base material. Creams prepared with those Chinese herbal monomers had lower Zeta potential value and poorer physical stability, and that those creams had great different microstructure information with cream base.

  18. 21 CFR 1210.25 - Permits for pasteurized milk or cream.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Permits for pasteurized milk or cream. 1210.25... UNDER THE FEDERAL IMPORT MILK ACT Permit Control § 1210.25 Permits for pasteurized milk or cream. Permits to ship or transport pasteurized milk or cream into the United States will be granted only...

  19. 21 CFR 131.25 - Whipped cream products containing flavoring or sweetening.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Whipped cream products containing flavoring or... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION MILK AND CREAM General Provisions § 131.25 Whipped cream products containing flavoring or sweetening. The unqualified name “whipped cream” should not be applied...

  20. 21 CFR 131.25 - Whipped cream products containing flavoring or sweetening.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Whipped cream products containing flavoring or... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION MILK AND CREAM General Provisions § 131.25 Whipped cream products containing flavoring or sweetening. The unqualified name “whipped cream” should not be applied...

  1. 21 CFR 131.25 - Whipped cream products containing flavoring or sweetening.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Whipped cream products containing flavoring or... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION MILK AND CREAM General Provisions § 131.25 Whipped cream products containing flavoring or sweetening. The unqualified name “whipped cream” should not be applied...

  2. 21 CFR 131.25 - Whipped cream products containing flavoring or sweetening.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Whipped cream products containing flavoring or... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION MILK AND CREAM General Provisions § 131.25 Whipped cream products containing flavoring or sweetening. The unqualified name “whipped cream” should not be applied...

  3. 40 CFR 60.1330 - How do I monitor the injection rate of activated carbon?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... activated carbon? 60.1330 Section 60.1330 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Requirements § 60.1330 How do I monitor the injection rate of activated carbon? If your municipal waste combustion unit uses activated carbon to control dioxins/furans or mercury emissions, you must meet...

  4. 40 CFR 60.1330 - How do I monitor the injection rate of activated carbon?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... activated carbon? 60.1330 Section 60.1330 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Requirements § 60.1330 How do I monitor the injection rate of activated carbon? If your municipal waste combustion unit uses activated carbon to control dioxins/furans or mercury emissions, you must meet...

  5. 40 CFR 60.1330 - How do I monitor the injection rate of activated carbon?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... activated carbon? 60.1330 Section 60.1330 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Requirements § 60.1330 How do I monitor the injection rate of activated carbon? If your municipal waste combustion unit uses activated carbon to control dioxins/furans or mercury emissions, you must meet...

  6. 40 CFR 60.1330 - How do I monitor the injection rate of activated carbon?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... activated carbon? 60.1330 Section 60.1330 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Requirements § 60.1330 How do I monitor the injection rate of activated carbon? If your municipal waste combustion unit uses activated carbon to control dioxins/furans or mercury emissions, you must meet...

  7. 40 CFR 60.1330 - How do I monitor the injection rate of activated carbon?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... activated carbon? 60.1330 Section 60.1330 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Requirements § 60.1330 How do I monitor the injection rate of activated carbon? If your municipal waste combustion unit uses activated carbon to control dioxins/furans or mercury emissions, you must meet...

  8. Probes to monitor activity of the paracaspase MALT1.

    PubMed

    Hachmann, Janna; Edgington-Mitchell, Laura E; Poreba, Marcin; Sanman, Laura E; Drag, Marcin; Bogyo, Matthew; Salvesen, Guy S

    2015-01-22

    The human paracaspase mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) plays a central role in nuclear factor-κB (NF-κB) signaling as both a protease and scaffolding protein. Knocking out MALT1 leads to impaired NF-κB signaling and failure to mount an effective immune response. However, it is unclear to which degree it is the scaffolding function versus the proteolytic activity of MALT1 that is essential. Previous work involving a MALT1 inhibitor with low selectivity suggests that the enzymatic function plays an important role in different cell lines. To help elucidate this proteolytic role of MALT1, we have designed activity-based probes that inhibit its proteolytic activity. The probes selectively label active enzyme and can be used to inhibit MALT1 and trace its activity profile, helping to create a better picture of the significance of the proteolytic function of MALT1.

  9. A portable multi-channel wireless NIRS device for muscle activity real-time monitoring.

    PubMed

    Yao, Pengfei; Guo, Weichao; Sheng, Xinjun; Zhang, Dingguo; Zhu, Xiangyang

    2014-01-01

    Near-infrared spectroscopy (NIRS) is a relative new technology in monitoring muscle oxygenation and hemo-dynamics. This paper presents a portable multi-channel wireless NIRS device for real-time monitoring of muscle activity. The NIRS sensor is designed miniaturized and modularized, to make multi-site monitoring convenient. Wireless communication is applied to data transmission avoiding of cumbersome wires and the whole system is highly integrated. Special care is taken to eliminate motion artifact when designing the NIRS sensor and attaching it to human skin. Besides, the system is designed with high sampling rate so as to monitor rapid oxygenation changes during muscle activities. Dark noise and long-term drift tests have been carried out, and the result indicates the device has a good performance of accuracy and stability. In vivo experiments including arterial occlusion and isometric voluntary forearm muscle contraction were performed, demonstrating the system has the ability to monitor muscle oxygenation parameters effectively even in exercise.

  10. Monitoring the Activation of the DNA Damage Response Pathway in a 3D Spheroid Model.

    PubMed

    Mondesert, Odile; Frongia, Céline; Clayton, Olivia; Boizeau, Marie-Laure; Lobjois, Valérie; Ducommun, Bernard

    2015-01-01

    Monitoring the DNA-Damage Response (DDR) activated pathway in multicellular tumor spheroid models is an important challenge as these 3D models have demonstrated their major relevance in pharmacological evaluation. Herein we present DDR-Act-FP, a fluorescent biosensor that allows detection of DDR activation through monitoring of the p21 promoter p53-dependent activation. We show that cells expressing the DDR-Act-FP biosensor efficiently report activation of the DDR pathway after DNA damage and its pharmacological manipulation using ATM kinase inhibitors. We also report the successful use of this assay to screen a small compound library in order to identify activators of the DDR response. Finally, using multicellular spheroids expressing the DDR-Act-FP we demonstrate that DDR activation and its pharmacological manipulation with inhibitory and activatory compounds can be efficiently monitored in live 3D spheroid model. This study paves the way for the development of innovative screening and preclinical evaluation assays.

  11. Toxigenic genes, spoilage potential, and antimicrobial resistance of Bacillus cereus group strains from ice cream.

    PubMed

    Arslan, Seza; Eyi, Ayla; Küçüksarı, Rümeysa

    2014-02-01

    Bacillus spp. can be recovered from almost every environment. It is also found readily in foods, where it may cause food spoilage and/or food poisoning due to its toxigenic and pathogenic nature, and extracellular enzymes. In this study, 29 Bacillus cereus group strains from ice cream were examined for the presence of following virulence genes hblC, nheA, cytK and ces genes, and tested for a range of the extracellular enzymes, and antimicrobial susceptibility. The strains were found to produce extracellular enzymes: proteolytic and lipolytic activity, gelatin hydrolysis and lecithinase production (100%), DNase production (93.1%) and amylase activity (93.1%). Of 29 strains examined, 24 (82.8%) showed hemolytic activity on blood agar. Beta-lactamase enzyme was only produced by 20.7% of B. cereus group. Among 29 B. cereus group from ice cream, nheA was the most common virulence gene detected in 44.8% of the strains, followed by hblC gene with 17.2%. Four (13.8%) of the 29 strains were positive for both hblC gene and nheA gene. Contrarily, cytK and ces genes were not detected in any of the strains. Antimicrobial susceptibility of ice cream isolates was tested to 14 different antimicrobial agents using the disc diffusion method. We detected resistance to penicillin and ampicillin with the same rate of 89.7%. Thirty-one percent of the strains were multiresistant to three or more antibiotics. This study emphasizes that the presence of natural isolates of Bacillus spp. harboring one or more enterotoxin genes, producing extracellular enzymes which may cause spoilage and acquiring antibiotic resistance might hold crucial importance in the food safety and quality.

  12. Seismic activity monitoring in the Izvorul Muntelui dam region

    NASA Astrophysics Data System (ADS)

    Borleanu, Felix; Otilia Placinta, Anca; Popa, Mihaela; Adelin Moldovan, Iren; Popescu, Emilia

    2016-04-01

    Earthquakes occurrences near the artificial water reservoirs are caused by stress variation due to the weight of water, weakness of fractures or faults and increasing of pore pressure in crustal rocks. In the present study we aim to investigate how Izvorul Muntelui dam, located in the Eastern Carpathians influences local seismicity. For this purpose we selected from the seismic bulletins computed within National Data Center of National Institute for Earth Physics, Romania, crustal events occurred between 984 and 2015 in a range of 0.3 deg around the artificial lake. Subsequently to improve the seismic monitoring of the region we applied a cross-correlation detector on the continuous recordings of Bicaz (BIZ) seismic stations. Besides the tectonic events we detected sources within this region that periodically generate artificial evens. We couldn't emphasize the existence of a direct correlation between the water level variations and natural seismicity of the investigated area.

  13. Production and evaluation of mineral and nutrient contents, chemical composition, and sensory properties of ice creams fortified with laboratory-prepared peach fibre

    PubMed Central

    Yangılar, Filiz

    2016-01-01

    Background In the coming years, a nutraceutical food may provide both physical and mental benefits that are commonly attributed to the active components of the food. Objective In this study, we determined the nutrient and mineral contents, sensory properties, and physical and chemical characteristics of ice creams manufactured using peach fibre at different concentrations (1 and 2%). Method A total of five experimental groups were formed: two types (from peach peel and pulp) of flour, two fibre concentrations (1 and 2%), and a control group without fibres. Results Flour obtained from peach pulp and peel was found to have a significant (p<0.05) effect on the chemical composition and elemental composition of ice cream samples, especially the rates of Ca, K, Mg, and P, which increased in the samples depending on the content of peach fibre. Sensory ratings and acceptability of ice creams decreased significantly with increasing peach peel fibre, whereas ice creams made with C (control) and B1 (ice creams made from 1% peach pulp fibre) was the highest scored by the panellists. Conclusions Peach fibre concentrates might be used as a good source of nutraceutical ingredients. PMID:27814781

  14. Physicochemical, bioactive, and sensory properties of persimmon-based ice cream: technique for order preference by similarity to ideal solution to determine optimum concentration.

    PubMed

    Karaman, Safa; Toker, Ömer Said; Yüksel, Ferhat; Çam, Mustafa; Kayacier, Ahmed; Dogan, Mahmut

    2014-01-01

    In the present study, persimmon puree was incorporated into the ice cream mix at different concentrations (8, 16, 24, 32, and 40%) and some physicochemical (dry matter, ash, protein, pH, sugar, fat, mineral, color, and viscosity), textural (hardness, stickiness, and work of penetration), bioactive (antiradical activity and total phenolic content), and sensory properties of samples were investigated. The technique for order preference by similarity to ideal solution approach was used for the determination of optimum persimmon puree concentration based on the sensory and bioactive characteristics of final products. Increase in persimmon puree resulted in a decrease in the dry matter, ash, fat, protein contents, and viscosity of ice cream mix. Glucose, fructose, sucrose, and lactose were determined to be major sugars in the ice cream samples including persimmon and increase in persimmon puree concentration increased the fructose and glucose content. Better melting properties and textural characteristics were observed for the samples with the addition of persimmon. Magnesium, K, and Ca were determined to be major minerals in the samples and only K concentration increased with the increase in persimmon content. Bioactive properties of ice cream samples improved and, in general, acetone-water extracts showed higher bioactivity compared with ones obtained using methanol-water extracts. The technique for order preference by similarity to ideal solution approach showed that the most preferred sample was the ice cream containing 24% persimmon puree.

  15. Fluorescence-Based Sensor for Monitoring Activation of Lunar Dust

    NASA Technical Reports Server (NTRS)

    Wallace, William T.; Jeevarajan, Antony S.

    2012-01-01

    This sensor unit is designed to determine the level of activation of lunar dust or simulant particles using a fluorescent technique. Activation of the surface of a lunar soil sample (for instance, through grinding) should produce a freshly fractured surface. When these reactive surfaces interact with oxygen and water, they produce hydroxyl radicals. These radicals will react with a terephthalate diluted in the aqueous medium to form 2-hydroxyterephthalate. The fluorescence produced by 2-hydroxyterephthalate provides qualitative proof of the activation of the sample. Using a calibration curve produced by synthesized 2-hydroxyterephthalate, the amount of hydroxyl radicals produced as a function of sample concentration can also be determined.

  16. Comparison of crotamiton 10% cream (Eurax) and permethrin 5% cream (Elimite) for the treatment of scabies in children.

    PubMed

    Taplin, D; Meinking, T L; Chen, J A; Sanchez, R

    1990-03-01

    Permethrin 5% cream (Elimite) was approved as a treatment for scabies by the U.S. Food and Drug Administration in September 1989. In a double-blinded, randomized study, it was compared with crotamiton 10% cream (Eurax) for the treatment of scabies in children 2 months to 5 years of age. Two weeks after a single overnight treatment, 14 (30%) of 47 children were cured with permethrin 5% cream, in contrast to only 6 of 47 (13%) of subjects treated with Eurax. Four weeks after treatment the figures were 89% and 60% cured for the two agents, respectively. In 10 of the 19 patients whose treatment failed, the condition became worse after therapy. The difference in efficacy in favor of permethrin was significant (P = 0.002). That agent also demonstrated greater effectiveness in reducing pruritus and secondary bacterial infections. Elimite offers a safe, efficacious, and cosmetically elegant alternative to Eurax in the treatment of scabies in children.

  17. Monitoring the activity of the Be star OT Geminorum

    NASA Astrophysics Data System (ADS)

    Arellano Ferro, A.; Sareyan, J. P.; Avila, J. J.; Gonzalez, F.; Dumont, M.; Geos

    1998-02-01

    Observations obtained in 1995-1996 of the Be star OT Geminorum are reported and show that in october 1995 the star reached a very active phase with large variations around a bright plateau, a phase of activity we have also distinguished in previous observations dating from 1960. The time scales involved are discussed and suggest that the violent variations of the activity propagate very quickly on the whole surface of the star or on a huge portion of it. No likely pulsation periods were found. The assumption that the detected activity is due to the effects of an hypothetical companion leads to conclude that such companion could not be detected by the present interferometric techniques. Partly based on observations obtained at the La Luz Observatory of the University of Guanajuato, Mexico.

  18. Monitoring Brain Activity with Protein Voltage and Calcium Sensors

    PubMed Central

    Storace, Douglas A.; Braubach, Oliver R.; Jin, Lei; Cohen, Lawrence B.; Sung, Uhna

    2015-01-01

    Understanding the roles of different cell types in the behaviors generated by neural circuits requires protein indicators that report neural activity with high spatio-temporal resolution. Genetically encoded fluorescent protein (FP) voltage sensors, which optically report the electrical activity in distinct cell populations, are, in principle, ideal candidates. Here we demonstrate that the FP voltage sensor ArcLight reports odor-evoked electrical activity in the in vivo mammalian olfactory bulb in single trials using both wide-field and 2-photon imaging. ArcLight resolved fast odorant-responses in individual glomeruli, and distributed odorant responses across a population of glomeruli. Comparisons between ArcLight and the protein calcium sensors GCaMP3 and GCaMP6f revealed that ArcLight had faster temporal kinetics that more clearly distinguished activity elicited by individual odorant inspirations. In contrast, the signals from both GCaMPs were a saturating integral of activity that returned relatively slowly to the baseline. ArcLight enables optical electrophysiology of mammalian neuronal population activity in vivo. PMID:25970202

  19. Cosmic Ray Energetic And Mass (CREAM) launch and operations, PSU Co-I

    NASA Astrophysics Data System (ADS)

    Coutu, Stephane

    This proposal covers the activities of the Penn State group on the BACCUS high-altitude balloon experiment in Antarctica and on the CREAM mission to the ISS. These projects together will achieve definitive measurements of the cosmic-ray elemental spectra into the PeV range (nuclei) and of cosmic-ray electrons into the TeV range, as well as detailed studies of secondary nuclei (such as B or the sub-Fe elements). These are the experimental measurements needed to sort out the details of cosmic-ray acceleration and propagation in the Galaxy, a long standing puzzle in particle astrophysics.

  20. Simultaneous programmed temperature GLC assay of phenol, chloroxylenol, and lidocaine hydrochloride in topical antiseptic cream.

    PubMed

    Palermo, P J; Lundberg, J B

    1978-11-01

    A simultaneous programmed temperature GLC assay for the active ingredients in a topical antiseptic cream is described. The sample is extracted directly using a dimethyl sulfoxide solution of p-cresol, 4-chlorophenol, and 2-amino-4-phenylthiazole as internal standards for phenol, chloroxylenol, and lidocaine hydrochloride, respectively. The resulting solution is chromatographed by temperature programming on an OV-225 column from 90 to 225 degrees. The internal standard calculation is accomplished using peak heights or peak areas. The relative standard deviation of all assays is less than 2%.

  1. Simultaneous HPLC Determination of Butenafine Hydrochloride and Betamethasone in a Cream Formulation

    PubMed Central

    Ankam, R.; Mukkanti, K.; Durgaprasad, S.; Khan, M.

    2009-01-01

    A fast, specific, accurate and precise reverse phase high performance liquid chromatographic method was developed for the simultaneous determination of butenafine hydrochloride and betamethasone in cream formulation. The determination was carried out on licrocart licrosphere RP-select B (250×4.6 mm, 5 μ) column in isocratic mode, the mobile phase consisting of 50 mM ammonium acetate buffer and acetonitrile in the ratio of 60:40, adjusted to pH 4.5 ± 0.1 with glacial acetic acid. The flow rate was 2.0 ml/min and eluent was monitored at 254 nm. The retention times of butenafine hydrochloride and betamethasone were 4.70 min and 7.76 min, respectively, and the resolution factor was greater than 4.0. Linearity of butenafine hydrochloride and betamethasone were in the range of 100-300 μg/ml and 5-15 μg/ml, respectively. The proposed method is also found to be precise and robust for the simultaneous determination of butenafine hydrochloride and betamethasone in cream formulation. PMID:20502575

  2. Comparison of in vitro release rates of acyclovir from cream formulations using vertical diffusion cells.

    PubMed

    Nallagundla, Sumalatha; Patnala, Srinivas; Kanfer, Isadore

    2014-08-01

    Acyclovir, indicated in the treatment of herpes labialis ("cold sores"), is formulated as semisolid topical dosage forms and marketed in numerous countries. Since the formulations of the various acyclovir products may differ from country to country, this study was undertaken to compare the in vitro release of acyclovir from various generic cream products available on the South African and Indian markets using the respective brand/innovator product as the reference product. The in vitro studies were carried out using vertical diffusion cells with a diffusional surface area of 1.767 cm(2) and various commercially available membranes. Normal saline was used as receptor fluid and the temperature maintained at 32 ± 0.5°C. The in vitro release comparisons were based on the recommendations described in the US Food and Drug Administration Draft Guidance for acyclovir ointment and the SUPAC-SS Guidance for non-sterile semisolid dosage forms. The release rates (slope) of the test (T) and the relevant reference product (R) were monitored and compared. The comparative release of acyclovir from the various generic formulations compared with the reference product was found to be within the limits of 75-133.33% with a 90% confidence interval. These experiments indicate that the generic acyclovir cream formulations exhibited release rates that were comparable to the innovator product and could be considered to be bioequivalent.

  3. Computerized cognitive training restores neural activity within the reality monitoring network in schizophrenia.

    PubMed

    Subramaniam, Karuna; Luks, Tracy L; Fisher, Melissa; Simpson, Gregory V; Nagarajan, Srikantan; Vinogradov, Sophia

    2012-02-23

    Schizophrenia patients suffer from severe cognitive deficits, such as impaired reality monitoring. Reality monitoring is the ability to distinguish the source of internal experiences from outside reality. During reality monitoring tasks, schizophrenia patients make errors identifying "I made it up" items, and even during accurate performance, they show abnormally low activation of the medial prefrontal cortex (mPFC), a region that supports self-referential cognition. We administered 80 hr of computerized training of cognitive processes to schizophrenia patients and found improvement in reality monitoring that correlated with increased mPFC activity. In contrast, patients in a computer games control condition did not show any behavioral or neural improvements. Notably, recovery in mPFC activity after training was associated with improved social functioning 6 months later. These findings demonstrate that a serious behavioral deficit in schizophrenia, and its underlying neural dysfunction, can be improved by well-designed computerized cognitive training, resulting in better quality of life.

  4. Monitoring leptin activity using the chicken leptin receptor.

    PubMed

    Hen, Gideon; Yosefi, Sera; Ronin, Ana; Einat, Paz; Rosenblum, Charles I; Denver, Robert J; Friedman-Einat, Miriam

    2008-05-01

    We report on the construction of a leptin bioassay based on the activation of chicken leptin receptor in cultured cells. A human embryonic kidney (HEK)-293 cell line, stably transfected with the full-length cDNA of chicken leptin receptor together with a STAT3-responsive reporter gene specifically responded to recombinant human and Xenopus leptins. The observed higher sensitivity of chicken leptin receptor to the former is in agreement with the degree of sequence similarity among these species (about 60 and 38% identical amino acids between humans and chickens, and between humans and Xenopus respectively). The specific activation of signal transduction through the chicken leptin receptor, shown here for the first time, suggests that the transition of Gln269 (implicated in the Gln-to-Pro Zucker fatty mutation in rats) to Glu in chickens does not impair its activity. Analysis of leptin-like activity in human serum samples of obese and lean subjects coincided well with leptin levels determined by RIA. Serum samples of pre- and post partum cows showed a tight correlation with the degree of adiposity. However, specific activation of the chicken leptin receptor in this assay was not observed with serum samples from broiler or layer chickens (representing fat and lean phenotypes respectively) or with those from turkey. Similar leptin receptor activation profiles were observed with cells transfected with human leptin receptor. Further work is needed to determine whether the lack of leptin-like activity in the chicken serum samples is due to a lack of leptin in this species or simply to a serum level of leptin that is below the detection threshold.

  5. Subsidence monitoring network: an Italian example aimed at a sustainable hydrocarbon E&P activity

    NASA Astrophysics Data System (ADS)

    Dacome, M. C.; Miandro, R.; Vettorel, M.; Roncari, G.

    2015-11-01

    According to the Italian law in order to start-up any new hydrocarbon exploitation activity, an Environmental Impact Assessment study has to be presented, including a monitoring plan, addressed to foresee, measure and analyze in real time any possible impact of the project on the coastal areas and on those ones in the close inland located. The occurrence of subsidence, that could partly be related to hydrocarbon production, both on-shore and off-shore, can generate great concern in those areas where its occurrence may have impacts on the local environment. ENI, following the international scientific community recommendations on the matter, since the beginning of 90's years, implemented a cutting-edge monitoring network, with the aim to prevent, mitigate and control geodynamics phenomena generated in the activity areas, with a particular attention to conservation and protection of environmental and territorial equilibrium, taking care of what is known as "sustainable development". The current ENI implemented monitoring surveys can be divided as: - Shallow monitoring: spirit levelling surveys, continuous GPS surveys in permanent stations, SAR surveys, assestimeter subsurface compaction monitoring, ground water level monitoring, LiDAR surveys, bathymetrical surveys. - Deep monitoring: reservoir deep compaction trough radioactive markers, reservoir static (bottom hole) pressure monitoring. All the information, gathered through the monitoring network, allow: 1. to verify if the produced subsidence is evolving accordingly with the simulated forecast. 2. to provide data to revise and adjust the prediction compaction models 3. to put in place the remedial actions if the impact exceeds the threshold magnitude originally agreed among the involved parties. ENI monitoring plan to measure and monitor the subsidence process, during field production and also after the field closure, is therefore intended to support a sustainable field development and an acceptable exploitation

  6. Topical symphytum herb concentrate cream against myalgia: a randomized controlled double-blind clinical study.

    PubMed

    Kucera, Miroslav; Barna, Milos; Horàcek, Ondrej; Kàlal, Jan; Kucera, Alexander; Hladìkova, Marie

    2005-01-01

    The effectiveness and tolerability of the topical Symphytum product Traumaplant (Harras Pharma Curarina, München, Germany) (10% active ingredient of a 2.5:1 aqueous-ethanolic pressed concentrate of freshly harvested, cultivated comfrey herb [Symphytum uplandicum Nyman], corresponding to 25 g of fresh herb per 100 g of cream) in the treatment of patients with myalgia (n=104) were tested against a 1% reference product (corresponding to 2.5 g of fresh comfrey herb in 100 g of cream; n=111). The primary efficacy parameter in this double-blind, reference- controlled, randomized, multicenter study of 215 patients with pain in the lower and upper back was pain in motion, assessed with the aid of a visual analogue scale. Secondary efficacy parameters included pain at rest, pain on palpation, and functional impairment. With high concentrations of the treatment product, amelioration of pain on active motion (P<5 x 10 -9 ), pain at rest (P<.001), and pain on palpation (P=5 x 10 -5 ) was significantly more pronounced than that attained with the reference product and was clinically highly relevant. A number needed to treat of 3.2 was calculated from the study results. Global efficacy was significantly better (P=1 x 10 -8 ) and onset of effects was faster (P=4 x 10 -7 ) with the high-concentration product. Tolerability of the highly concentrated study product was good to excellent in all patients. Study results confirm the known anti-inflammatory and analgesic effects of topical (Symphytum cream. As a new finding, applicability in certain forms of back pain can be concluded.

  7. Smolt Monitoring Activities at Little Goose Dam; 1996 Annual Report.

    SciTech Connect

    Setter, Ann

    1997-07-01

    The juvenile fish facility at Little Goose Dam is operated seasonally to collect and bypass downstream migrating smolts and keep them from passing through the turbine blades. Fish are diverted from turbines by traveling screens as they sound in the forebay to pass the dam. A small percentage of the passing fish are sampled on a daily basis to provide information on fish condition, species composition, migration timing, and size distribution. Oregon Department of Fish and Wildlife personnel perform daily fish sampling and data collection. Physical operation of the facility is the responsibility of the US Army Corps of Engineers. Data is reported to the Fish Passage Center daily by means of electronic data transfer. Funding for this project was provided through the Smolt Monitoring Program administered by the Fish Passage Center. Overall, the number of fish collected and sampled in 1996 was a reduction from the previous years of operation. The 1996 migration season was characterized by higher than average flows and greater spill frequency at the dam. It was the first year that coho salmon were obtained in the sample. The predominant species collected was steelhead with hatchery fish outnumbering wild fish by a ratio of 8:1. An increased emphasis was placed on gas bubble trauma examination and a routine, consistent effort was implemented using a protocol established by the Fish Passage Center. The objective of the gas bubble trauma (GBT) examinations was to document the relative incidence of symptoms throughout the migration season.

  8. A review of market monitoring activities at U.S. independent system operators

    SciTech Connect

    Lesieutre, Bernard C.; Goldman, Charles; Bartholomew, Emily

    2004-01-01

    Policymakers have increasingly recognized the structural impediments to effective competition in electricity markets, which has resulted in a renewed emphasis on the need for careful market design and market monitoring in wholesale and retail electricity markets. In this study, we review the market monitoring activities of four Independent System Operators in the United States, focusing on such topics as the organization of an independent market monitoring unit (MMU), the role and value of external market monitors, performance metrics and indices to aid in market analysis, issues associated with access to confidential market data, and market mitigation and investigation authority. There is consensus across the four ISOs that market monitoring must be organizationally independent from market participants and that ISOs should have authority to apply some degree of corrective actions on the market, though scope and implementation differ across the ISOs. Likewise, current practices regarding access to confidential market data by state energy regulators varies somewhat by ISO. Drawing on our interviews and research, we present five examples that illustrate the impact and potential contribution of ISO market monitoring activities to enhance functioning of wholesale electricity markets. We also discuss several key policy and implementation issues that Western state policymakers and regulators should consider as market monitoring activities evolve in the West.

  9. Hemispheric Asymmetries in the Activation and Monitoring of Memory Errors

    ERIC Educational Resources Information Center

    Giammattei, Jeannette; Arndt, Jason

    2012-01-01

    Previous research on the lateralization of memory errors suggests that the right hemisphere's tendency to produce more memory errors than the left hemisphere reflects hemispheric differences in semantic activation. However, all prior research that has examined the lateralization of memory errors has used self-paced recognition judgments. Because…

  10. Monitoring Affect States during Effortful Problem Solving Activities

    ERIC Educational Resources Information Center

    D'Mello, Sidney K.; Lehman, Blair; Person, Natalie

    2010-01-01

    We explored the affective states that students experienced during effortful problem solving activities. We conducted a study where 41 students solved difficult analytical reasoning problems from the Law School Admission Test. Students viewed videos of their faces and screen captures and judged their emotions from a set of 14 states (basic…

  11. Monitoring activity in neural circuits with genetically encoded indicators

    PubMed Central

    Broussard, Gerard J.; Liang, Ruqiang; Tian, Lin

    2014-01-01

    Recent developments in genetically encoded indicators of neural activity (GINAs) have greatly advanced the field of systems neuroscience. As they are encoded by DNA, GINAs can be targeted to genetically defined cellular populations. Combined with fluorescence microscopy, most notably multi-photon imaging, GINAs allow chronic simultaneous optical recordings from large populations of neurons or glial cells in awake, behaving mammals, particularly rodents. This large-scale recording of neural activity at multiple temporal and spatial scales has greatly advanced our understanding of the dynamics of neural circuitry underlying behavior—a critical first step toward understanding the complexities of brain function, such as sensorimotor integration and learning. Here, we summarize the recent development and applications of the major classes of GINAs. In particular, we take an in-depth look at the design of available GINA families with a particular focus on genetically encoded calcium indicators (GCaMPs), sensors probing synaptic activity, and genetically encoded voltage indicators. Using the family of the GCaMP as an example, we review established sensor optimization pipelines. We also discuss practical considerations for end users of GINAs about experimental methods including approaches for gene delivery, imaging system requirements, and data analysis techniques. With the growing toolbox of GINAs and with new microscopy techniques pushing beyond their current limits, the age of light can finally achieve the goal of broad and dense sampling of neuronal activity across time and brain structures to obtain a dynamic picture of brain function. PMID:25538558

  12. An investigation into the use of low-frequency dielectric spectroscopy as a means of characterizing the structure of creams based on Aqueous Cream BP.

    PubMed

    Goggin, P L; He, R; Craig, D Q; Gregory, D P

    1998-05-01

    A range of creams based on Aqueous Cream BP have been analyzed using low-frequency dielectric spectroscopy, with accompanying circuit modeling in combination with rheological and microscopic supportive techniques, to explore the use of the dielectric approach as a novel means of characterizing cream systems. Creams based on the formula for Aqueous Cream BP were produced by hand-mixing and mechanical mixing, with and without the inclusion of the preservative phenoxyethanol. Dielectric analysis was performed over a frequency range of 10(-2)-10(5) Hz. Cream samples were also examined using stress scan rheology and differential interference contrast microscopy. Dielectric analysis indicated that the presence of preservative decreased the capacitance and loss of the creams. The responses were modeled in terms of a dispersive capacitance in series with two RC circuits (series and parallel). Rheological studies indicated higher viscosities for the hand-mixed and unpreserved systems. Differential interference contrast microscopy showed marked differences in the distribution of the oil droplets, depending on the method of mixing. The study has demonstrated that dielectric spectroscopy, with accompanying circuit analysis, may be used as a means of modeling the structure of cream systems. The investigation has also shown that the formulation and preparation method of Aqueous Cream BP may have a profound effect on sample structure.

  13. Testing the applicability of rapid on-site enzymatic activity detection for surface water monitoring

    NASA Astrophysics Data System (ADS)

    Stadler, Philipp; Vogl, Wolfgang; Juri, Koschelnik; Markus, Epp; Maximilian, Lackner; Markus, Oismüller; Monika, Kumpan; Peter, Strauss; Regina, Sommer; Gabriela, Ryzinska-Paier; Farnleitner Andreas, H.; Matthias, Zessner

    2015-04-01

    On-site detection of enzymatic activities has been suggested as a rapid surrogate for microbiological pollution monitoring of water resources (e.g. using glucuronidases, galactosidases, esterases). Due to the possible short measuring intervals enzymatic methods have high potential as near-real time water quality monitoring tools. This presentation describes results from a long termed field test. For twelve months, two ColiMinder devices (Vienna Water Monitoring, Austria) for on-site determination of enzymatic activity were tested for stream water monitoring at the experimental catchment HOAL (Hydrological Open Air Laboratory, Center for Water Resource Systems, Vienna University of Technology). The devices were overall able to follow and reflect the diverse hydrological and microbiological conditions of the monitored stream during the test period. Continuous data in high temporal resolution captured the course of enzymatic activity in stream water during diverse rainfall events. The method also proofed sensitive enough to determine diurnal fluctuations of enzymatic activity in stream water during dry periods. The method was able to capture a seasonal trend of enzymatic activity in stream water that matches the results gained from Colilert18 analysis for E. coli and coliform bacteria of monthly grab samples. Furthermore the comparison of ColiMinder data with measurements gained at the same test site with devices using the same method but having different construction design (BACTcontrol, microLAN) showed consistent measuring results. Comparative analysis showed significant differences between measured enzymatic activity (modified fishman units and pmol/min/100ml) and cultivation based analyses (most probable number, colony forming unit). Methods of enzymatic activity measures are capable to detect ideally the enzymatic activity caused by all active target bacteria members, including VBNC (viable but nonculturable) while cultivation based methods cannot detect VBNC

  14. Ebola active monitoring system for travelers returning from West Africa—Georgia, 2014-2015.

    PubMed

    Parham, Mary; Edison, Laura; Soetebier, Karl; Feldpausch, Amanda; Kunkes, Audrey; Smith, Wendy; Guffey, Taylor; Fetherolf, Romana; Sanlis, Kathryn; Gabel, Julie; Cowell, Alex; Drenzek, Cherie

    2015-04-10

    The Ebola virus disease (Ebola) epidemic in West Africa has so far produced approximately 25,000 cases, more than 40 times the number in any previously documented Ebola outbreak. Because of the risk for imported disease from infected travelers, in October 2014 CDC recommended that all travelers to the United States from Ebola-affected countries receive enhanced entry screening and postarrival active monitoring for Ebola signs or symptoms until 21 days after their departure from an Ebola-affected country. The state of Georgia began its active monitoring program on October 25, 2014. The Georgia Department of Public Health (DPH) modified its existing, web-based electronic notifiable disease reporting system to create an Ebola Active Monitoring System (EAMS). DPH staff members developed EAMS from conceptualization to implementation in 6 days. In accordance with CDC recommendations, "low (but not zero) risk" travelers are required to report their daily health status to DPH, and the EAMS dashboard enables DPH epidemiologists to track symptoms and compliance with active monitoring. Through March 31, 2015, DPH monitored 1,070 travelers, and 699 (65%) used their EAMS traveler login instead of telephone or e-mail to report their health status. Medical evaluations were performed on 30 travelers, of whom three were tested for Ebola. EAMS has enabled two epidemiologists to monitor approximately 100 travelers daily, and to rapidly respond to travelers reporting signs and symptoms of potential Ebola virus infection. Similar electronic tracking systems might be useful for other jurisdictions.

  15. 21 CFR 133.134 - Cream cheese with other foods.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... content of the mixture is 60 percent by weight. The minimum milkfat is 33 percent by weight of the cream cheese and in no case less than 27 percent of the finished food. The moisture and fat contents will be determined by the methods described in § 133.5, except that the method for determination of fat content...

  16. 21 CFR 133.134 - Cream cheese with other foods.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... content of the mixture is 60 percent by weight. The minimum milkfat is 33 percent by weight of the cream cheese and in no case less than 27 percent of the finished food. The moisture and fat contents will be determined by the methods described in § 133.5, except that the method for determination of fat content...

  17. 21 CFR 133.134 - Cream cheese with other foods.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... content of the mixture is 60 percent by weight. The minimum milkfat is 33 percent by weight of the cream cheese and in no case less than 27 percent of the finished food. The moisture and fat contents will be determined by the methods described in § 133.5, except that the method for determination of fat content...

  18. 21 CFR 133.134 - Cream cheese with other foods.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... content of the mixture is 60 percent by weight. The minimum milkfat is 33 percent by weight of the cream cheese and in no case less than 27 percent of the finished food. The moisture and fat contents will be determined by the methods described in § 133.5, except that the method for determination of fat content...

  19. Selective assay of benzoyl peroxide in lotions and creams.

    PubMed

    Daly, R E; Lomner, J J; Chafetz, L

    1975-12-01

    A selective titrimetric method for the determination of benzoyl peroxide in lotions and creams was developed. It is based on the work of Horner and Jürgens, in which diacylperoxides, dialkylperoxides, peracids, and alkylhydroperoxides can be determined selectively by iodometry and acidimetry. The proposed assay is stability indicating with respect to peracids. Good recovery data were obtained.

  20. Delicious ice cream, why does salt thaw ice?

    NASA Astrophysics Data System (ADS)

    Bagnoli, Franco

    2016-04-01

    During winter, we use to spread salt to thaw ice on the streets. In a physics show, one can be almost sure that after showing this effect, the answer to what happens to temperature will be "it increases". But no! It goes down, in such amount that one can complement the show by producing hand-made ice creams [1].

  1. Ice Cream/I Scream for YA Books

    ERIC Educational Resources Information Center

    Gallo, Don

    2010-01-01

    From a 40-year perspective, Don Gallo examines the field of young adult literature, comparing it to ice cream--its various flavors and levels of richness. The article proclaims the profundity of the field and the quality of its writers, summarizes historical highlights, defends it against its detractors, and explains the importance of helping…

  2. Teaching Process Engineering Principles Using an Ice Cream Maker

    ERIC Educational Resources Information Center

    Kaletunc, Gonul; Duemmel, Kevin; Gecik, Christopher

    2007-01-01

    The ice cream laboratory experiment is designed to illustrate and promote discussion of several engineering and science topics including material and energy balances, heat transfer, freezing, mass transfer, mixing, viscosity, and freezing point depression in a sophomore level engineering class. A pre-lab assignment requires the students to develop…

  3. 21 CFR 878.4470 - Surgeon's gloving cream.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Surgeon's gloving cream. 878.4470 Section 878.4470 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4470 Surgeon's gloving...

  4. 21 CFR 878.4470 - Surgeon's gloving cream.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Surgeon's gloving cream. 878.4470 Section 878.4470 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4470 Surgeon's gloving...

  5. 21 CFR 878.4470 - Surgeon's gloving cream.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Surgeon's gloving cream. 878.4470 Section 878.4470 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4470 Surgeon's gloving...

  6. 21 CFR 878.4470 - Surgeon's gloving cream.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Surgeon's gloving cream. 878.4470 Section 878.4470 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4470 Surgeon's gloving...

  7. New sensitizers and rapid monitoring of their photodynamic activity

    NASA Astrophysics Data System (ADS)

    Torshina, Nadezgda L.; Posypanova, Anna M.; Volkova, Anna I.

    1996-04-01

    At present, there are lots and lots of chemical compounds that are, to a certain extent, photodynamically active. Therefore, the task of carrying out the expressive screening of such compounds has been raised sharply enough. The primary screening in vitro of compounds, with the help of biological liquids, is notable for quickness and cheapness at the same time, it is possible to determine the comparative characteristics of compounds by their photodynamical activity. Decomposition of albumins of a mixture of photosensitizer and biological liquid when irradiating with light is the basis of this method. Efficiency of decomposition of components of biological liquids is determined using biochemical reactions (e.g., those for determining the total albumins or blood hemoglobin). Subsequently, with a sufficient efficiency of a photosensitizer, it will be possible to carry out a study in vivo, with the purpose of establishing accumulation of preparations in tumor.

  8. Monitoring Monitoring Evolving Activity at Popocatepetl Volcano, Mexico, 2000-2001

    NASA Astrophysics Data System (ADS)

    Martin-DelPozzo, A.; Aceves, F.; Bonifaz, R.; Humberto, S.

    2001-12-01

    After 6 years of small eruptions, activity at Mexico's 5,452m high Popocatepetl Volcano in central Mexico, peaked in the December 2000-January 2001 eruptions. Precursors included an important increase in seismicity as well as in magmatic components of spring water and small scale deformation which resulted in growth of a new crater dome from January 16 on. Evacuation of the towns nearest the volcano over Christmas was decided because of the possibility of pyroclastic flows. During the previous years, crater dome growth, contraction and explosive clearing has dominated the activity. The January 22 eruption produced an eruption column approximately 17km high with associated pyroclastic flows. Ejecta was composed of both basic and evolved scoria and pumice and dome lithics. A large proportion of the juvenile material was intermediate between these 2 endmenbers (59-63percent SiO2 and 3.5 to 5.5 MgO) consistent with a small basic pulse entering a more evolved larger batch of magma. The January eruption left a large pit which has been partially infilled by another crater dome this August 2001.

  9. Phosphate-Modified Nucleotides for Monitoring Enzyme Activity.

    PubMed

    Ermert, Susanne; Marx, Andreas; Hacker, Stephan M

    2017-04-01

    Nucleotides modified at the terminal phosphate position have been proven to be interesting entities to study the activity of a variety of different protein classes. In this chapter, we present various types of modifications that were attached as reporter molecules to the phosphate chain of nucleotides and briefly describe the chemical reactions that are frequently used to synthesize them. Furthermore, we discuss a variety of applications of these molecules. Kinase activity, for instance, was studied by transfer of a phosphate modified with a reporter group to the target proteins. This allows not only studying the activity of kinases, but also identifying their target proteins. Moreover, kinases can also be directly labeled with a reporter at a conserved lysine using acyl-phosphate probes. Another important application for phosphate-modified nucleotides is the study of RNA and DNA polymerases. In this context, single-molecule sequencing is made possible using detection in zero-mode waveguides, nanopores or by a Förster resonance energy transfer (FRET)-based mechanism between the polymerase and a fluorophore-labeled nucleotide. Additionally, fluorogenic nucleotides that utilize an intramolecular interaction between a fluorophore and the nucleobase or an intramolecular FRET effect have been successfully developed to study a variety of different enzymes. Finally, also some novel techniques applying electron paramagnetic resonance (EPR)-based detection of nucleotide cleavage or the detection of the cleavage of fluorophosphates are discussed. Taken together, nucleotides modified at the terminal phosphate position have been applied to study the activity of a large diversity of proteins and are valuable tools to enhance the knowledge of biological systems.

  10. A transgenic zebrafish model for monitoring glucocorticoid receptor activity

    PubMed Central

    Krug, Randall G.; Poshusta, Tanya L.; Skuster, Kimberly J.; Berg, MaKayla R.; Gardner, Samantha L.; Clark, Karl J.

    2014-01-01

    Gene regulation resulting from glucocorticoid receptor and glucocorticoid response element interactions is a hallmark feature of stress response signaling. Imbalanced glucocorticoid production and glucocorticoid receptor activity have been linked to socio-economically crippling neuropsychiatric disorders, and accordingly there is a need to develop in vivo models to help understand disease progression and management. Therefore, we developed the transgenic SR4G zebrafish reporter line with six glucocorticoid response elements used to promote expression of a short half-life green fluorescent protein following glucocorticoid receptor activation. Herein, we document the ability of this reporter line to respond to both chronic and acute exogenous glucocorticoid treatment. The green fluorescent protein expression in response to transgene activation was high in a variety of tissues including the brain, and provided single cell resolution in the effected regions. The specificity of these responses is demonstrated using the partial agonist mifepristone and mutation of the glucocorticoid receptor. Importantly, the reporter line also modeled the temporal dynamics of endogenous stress response signaling, including the increased production of the glucocorticoid cortisol following hyperosmotic stress and the fluctuations of basal cortisol concentrations with the circadian rhythm. Taken together, these results characterize our newly developed reporter line for elucidating environmental or genetic modifiers of stress response signaling, which may provide insights to the neuronal mechanisms underlying neuropsychiatric disorders such as major depressive disorder. PMID:24679220

  11. Retention and migration of alprostadil cream applied topically to the glans meatus for erectile dysfunction.

    PubMed

    Yeager, J; Beihn, R M

    2005-01-01

    Retention and migration of a specially designed alprostadil transdermal cream was assessed after single-dose administration to the glans meatus of the penis. Seven men were enrolled in this two-way crossover study. Three subjects self-administered the radio-labeled alprostadil transdermal cream (approximately 100 mg of cream containing 300 microg alprostadil) by inserting the tip of the dispenser into the meatus. In three others, the dose was administered by dispensing the cream dropwise into the metal opening without touching the penis (the preferred and directed method). Retention and migration of the cream mass was measured in the penis with a gamma scintillation camera. The alprostadil transdermal cream was retained in the fossa navicularis at or near 99% in five of six subjects regardless of the method of dosing, thus indicating that the cream formulation performed as designed. A mild, transient burning sensation in the penis was the most common adverse event.

  12. Effect of galactooligosaccharide addition on the physical, optical, and sensory acceptance of vanilla ice cream.

    PubMed

    Balthazar, C F; Silva, H L A; Celeguini, R M S; Santos, R; Pastore, G M; Junior, C A Conte; Freitas, M Q; Nogueira, L C; Silva, M C; Cruz, A G

    2015-07-01

    The effect of the addition of galactooligosaccharide (GOS) on the physicochemical, optical, and sensory characteristics of ice cream was investigated. Vanilla ice cream was supplemented with 0, 1.5, and 3.0% (wt/wt) GOS and characterized for pH, firmness, color, melting, overrun, as well as subjected to a discriminative sensory test (triangle test). For comparison purposes, ice creams containing fructooligosaccharide were also manufactured. The GOS ice creams were characterized by increased firmness and lower melting rates. Different perceptions were reported in the sensory evaluation for the 3.0% GOS ice cream when compared with the control, which was not observed for the fructooligosaccharide ice cream. Overall, the findings suggest it is possible to produce GOS ice cream with improved stability in relation to the physicochemical parameters and sensory perception.

  13. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials

    PubMed Central

    Smith, Doug B.; Jacobson, Bert H.

    2011-01-01

    Objective The purpose of this study was to determine the effect of 2 concentrations of topical, comfrey-based botanical creams containing a blend of tannic acid and eucalyptus to a eucalyptus reference cream on pain, stiffness, and physical functioning in those with primary osteoarthritis of the knee. Methods Forty-three male and female subjects (45-83 years old) with diagnosed primary osteoarthritis of the knee who met the inclusion criteria were entered into the study. The subjects were randomly assigned to 1 of 3 treatment groups: 10% or 20% comfrey root extract (Symphytum officinale L.) or a placebo cream. Outcomes of pain, stiffness, and functioning were done on the Western Ontario and MacMaster Universities Osteoarthritis Index. Participants applied the cream 3× a day for 6 weeks and were evaluated every 2 weeks during the treatment. Results Repeated-measures analyses of variance yielded significant differences in all of the Western Ontario and MacMaster Universities Osteoarthritis Index categories (pain P < .01, stiffness P < .01, daily function P < .01), confirming that the 10% and 20% comfrey-based creams were superior to the reference cream. The active groups each had 2 participants who had temporary and minor adverse reactions of skin rash and itching, which were rapidly resolved by modifying applications. Conclusion Both active topical comfrey formulations were effective in relieving pain and stiffness and in improving physical functioning and were superior to placebo in those with primary osteoarthritis of the knee without serious adverse effects. PMID:22014903

  14. 30 CFR 580.29 - Will BOEM monitor the environmental effects of my activity?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Will BOEM monitor the environmental effects of my activity? 580.29 Section 580.29 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF... environmental effects of my activity? We will evaluate the potential of proposed prospecting or...

  15. 30 CFR 580.29 - Will BOEM monitor the environmental effects of my activity?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Will BOEM monitor the environmental effects of my activity? 580.29 Section 580.29 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF... environmental effects of my activity? We will evaluate the potential of proposed prospecting or...

  16. 30 CFR 580.29 - Will BOEM monitor the environmental effects of my activity?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Will BOEM monitor the environmental effects of my activity? 580.29 Section 580.29 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF... environmental effects of my activity? We will evaluate the potential of proposed prospecting or...

  17. Magneto-impedance sensor for quasi-noncontact monitoring of breathing, pulse rate and activity status

    NASA Astrophysics Data System (ADS)

    Corodeanu, S.; Chiriac, H.; Radulescu, L.; Lupu, N.

    2014-05-01

    Results on the development and testing of a novel magnetic sensor based on the detection of the magneto-impedance variation due to changes in the permeability of an amorphous wire are reported. The proposed application is the quasi-noncontact monitoring of the breathing frequency and heart rate for diagnosing sleep disorders. Patient discomfort is significantly decreased by transversally placing the sensitive element onto the surface of a flexible mattress in order to detect its deformation associated with cardiorespiratory activity and body movements. The developed sensor has a great application potential in monitoring the vital signs during sleep, with special advantages for children sleep monitoring.

  18. Monitoring gross alpha and beta activity in liquids by using ZnS(Ag) scintillation detectors

    SciTech Connect

    Stevanato, L.; Cester, D.; Filippi, D.; Lunardon, M.; Mistura, G.; Moretto, S.; Viesti, G.; Badocco, D.; Pastore, P.; Romanini, F.

    2015-07-01

    In this work the possibility of monitoring gross alpha and beta activity in liquids using EJ-444 was investigated. Specific tests were carried out to determine the change of the detector properties in water tests. Possible protecting coating is also proposed and tested. Alpha/beta real-time monitoring in liquids is a goal of the EU project TAWARA{sub R}TM. (authors)

  19. Synbiotic Amazonian palm berry (açai, Euterpe oleracea Mart.) ice cream improved Lactobacillus rhamnosus GG survival to simulated gastrointestinal stress.

    PubMed

    Costa, Mayra Garcia Maia; Ooki, Gabriela Namur; Vieira, Antônio Diogo Silva; Bedani, Raquel; Saad, Susana Marta Isay

    2017-02-22

    The effect of açai pulp ice cream and of its supplementation with inulin (I), whey protein concentrate (WC), and/or whey protein isolate (WI) on the viability and resistance to simulated gastrointestinal stress of the probiotic Lactobacillus (Lb.) rhamnosus GG strain throughout storage at -18 °C for up to 112 days was evaluated and morphological changes during stress were monitored. Lb. rhamnosus GG viability was stable in all formulations for up to 112 days of storage, preserving populations around 9 log CFU g(-1). Compared to the fresh culture, Lb. rhamnosus GG showed higher survival under simulated gastrointestinal conditions when incorporated into açai ice cream, indicating that the presence of the food matrix contributed to the microorganism survival. A reduction of at least 5 log cycles of Lb. rhamnosus GG was observed in all formulations after the gastrointestinal simulation in all storage periods assessed. The addition of I, WC, and/or WI did not show any significant effect on the probiotic survival under simulated gastrointestinal stress (p < 0.05). Compared to the fresh culture, fewer morphological changes were observed when the probiotic was added to ice cream. Thus, the açai pulp ice cream was shown to be a suitable matrix for Lb. rhamnosus GG, improving its survival under in vitro simulated gastrointestinal conditions.

  20. Monitoring Criminal Activity through Invisible Fluorescent "Peptide Coding" Taggants.

    PubMed

    Gooch, James; Goh, Hilary; Daniel, Barbara; Abbate, Vincenzo; Frascione, Nunzianda

    2016-04-19

    Complementing the demand for effective crime reduction measures are the increasing availability of commercial forensic "taggants", which may be used to physically mark an object in order to make it uniquely identifiable. This study explores the use of a novel "peptide coding" reagents to establish evidence of contact transfer during criminal activity. The reagent, containing a fluorophore dispersed within an oil-based medium, also includes a unique synthetic peptide sequence that acts as a traceable "code" to identify the origin of the taggant. The reagent is detectable through its fluorescent properties, which then allows the peptide to be recovered by swabbing and extracted for electrospray ionization-mass spectrometry (ESI-MS) analysis via a simple liquid-liquid extraction procedure. The performance of the reagent in variable conditions that mimic the limits of a real world use are investigated.

  1. Active System for Electromagnetic Perturbation Monitoring in Vehicles

    NASA Astrophysics Data System (ADS)

    Matoi, Adrian Marian; Helerea, Elena

    Nowadays electromagnetic environment is rapidly expanding in frequency domain and wireless services extend in terms of covered area. European electromagnetic compatibility regulations refer to limit values regarding emissions, as well as procedures for determining susceptibility of the vehicle. Approval procedure for a series of cars is based on determining emissions/immunity level for a few vehicles picked randomly from the entire series, supposing that entire vehicle series is compliant. During immunity assessment, the vehicle is not subjected to real perturbation sources, but exposed to electric/magnetic fields generated by laboratory equipment. Since current approach takes into account only partially real situation regarding perturbation sources, this paper proposes an active system for determining electromagnetic parameters of vehicle's environment, that implements a logical diagram for measurement, satisfying the imposed requirements. This new and original solution is useful for EMC assessment of hybrid and electrical vehicles.

  2. Individual differences in epistemic motivation and brain conflict monitoring activity.

    PubMed

    Kossowska, Małgorzata; Czarnek, Gabriela; Wronka, Eligiusz; Wyczesany, Miroslaw; Bukowski, Marcin

    2014-06-06

    It is well documented that motivation toward closure (NFC), defined as a desire for a quick and unambiguous answer to a question and an aversion to uncertainty, is linked to more structured, rigid, and persistent cognitive styles. However, the neurocognitive correlates of NFC have never been tested. Thus, using event-related potentials, we examined the hypothesis that NFC is associated with the neurocognitive process for detecting discrepancies between response tendencies and higher level intentions. We found that greater NFC is associated with lower conflict-related anterior cingulate activity, suggesting lower sensitivity to cues for altering a habitual response pattern and lower sensitivity to committing errors. This study provides evidence that high NFC acts as a bulwark against anxiety-producing uncertainty and minimizes the experience of error.

  3. A comparison of red blood cell transfusion utilization between anti-activated factor X and activated partial thromboplastin monitoring in patients receiving unfractionated heparin.

    PubMed

    Belk, K W; Laposata, M; Craver, C

    2016-11-01

    Essentials Anti-activated factor X (Anti-Xa) monitoring is more precise than activated partial thromboplastin (aPTT). 20 804 hospitalized cardiovascular patients monitored with Anti-Xa or aPTT were analyzed. Adjusted transfusion rates were significantly lower for patients monitored with Anti-Xa. Adoption of Anti-Xa protocols could reduce transfusions among cardiovascular patients in the US.

  4. Production of probiotic cheese (cheddar-like cheese) using enriched cream fermented by Bifidobacterium infantis.

    PubMed

    Daigle, A; Roy, D; Bélanger, G; Vuillemard, J C

    1999-06-01

    Probiotic cheeses (Cheddar-like cheese) were produced with microfiltered milk standardized with cream enriched with native phosphocaseinate retentate and fermented by Bifidobacterium infantis. During the manufacture and storage of cheeses, viability of the bifidobacteria was determined. Biochemical changes such as proteolysis, sugar metabolism, and organic acids production were estimated. No bifidobacteria growth was observed during cheese-making steps. Bifidobacteria survived very well in cheeses packed in vacuum sealed bags kept at 4 degrees C for 84 d and remained above 3 x 10(6) cfu/g of cheese. No significant difference was observed between cheeses produced with or without bifidobacteria for fat, protein, moisture, salt, ash, or pH. After 12 wk of storage, more than 56% of the as1-CN was hydrolyzed in cheeses that were produced with bifidobacteria and inoculated at 10(8) cfu/g in the cream, and > 45% of hydrolysis was observed in the control cheese. However, no significant differences in the electrophoretic sodium dodecyl sulfate-PAGE patterns were observed in cheeses at any period of storage. At the first day after manufacture, lactose was completely hydrolyzed in cheeses made with bifidobacteria, which suggested high beta-galactosidase activity by B. infantis. Small quantities of acetic acid were detected in bifidus cheeses. The results indicated that B. infantis introduced into hard pressed cheese exhibited excellent viability during storage for 12 wk and could be metabolically active.

  5. Use of a consumer market activity monitoring and feedback device improves exercise capacity and activity levels in COPD.

    PubMed

    Caulfield, Brian; Kaljo, Indira; Donnelly, Seamas

    2014-01-01

    COPD is associated with a gradual decline in physical activity, which itself contributes to a worsening of the underlying condition. Strategies that improve physical activity levels are critical to halt this cycle. Wearable sensor based activity monitoring and persuasive feedback might offer a potential solution. However it is not clear just how much intervention might be needed in this regard - i.e. whether programmes need to be tailored specifically for the target clinical population or whether more simple activity monitoring and feedback solutions, such as that offered in consumer market devices, might be sufficient. This research was carried out to investigate the impact of 4 weeks of using an off the shelf consumer market activity monitoring and feedback application on measures of physical activity, exercise capacity, and health related quality of life in a population of 10 Stage I and II COPD patients. Results demonstrate a significant and positive effect on exercise capacity (measured using a 6-minute walk test) and activity levels (measured in terms of average number of steps per hour) yet no impact on health related quality of life (St Georges Respiratory Disease Questionnaire).

  6. The comparative efficacy and safety of 5% povidone-iodine cream for topical antisepsis.

    PubMed

    Stahl-Bayliss, C M; Grandy, R P; Fitzmartin, R D; Chelle, C; Oshlack, B; Goldenheim, P D

    1990-01-01

    A 5% povidone-iodine cream (Betadine Cream, The Purdue Frederick Company, Norwalk, Conn.) was tested extensively to determine its safety and efficacy. Results of in vitro microbiologic comparison found that a representative panel of vegetative test organisms couldn't be recovered after 60 seconds or less exposure to povidone-iodine (PVP-I) cream, whereas the kill time of the combination-antibiotic cream (Neosporin Cream, Burroughs Wellcome, Research Triangle Park, NC) exceeded 15 minutes for at least half of vegetative organisms. PVP-I cream produced a log reduction of Bacillus pumilis spores after less than one hour's exposure; the antibiotic cream did not. Both PVP-I and antibiotic creams were essentially non-irritating in human and in vivo animal studies. In open wounds, 5% PVP-I cream caused little or no burning and pain upon application. In human comparisons, artificially induced, standardized lesions inoculated with Staphylococcus aureus, were treated twice daily with PVP-I cream or triple-antibiotic ointment (Neosporin Ointment, Burroughs Wellcome, Research Triangle Park, NC) over three weeks. Both caused significantly reduced bacterial counts (p less than 0.001), and significantly faster healing (p less than 0.05) than no treatment.

  7. Assessing Human Activity in Elderly People Using Non-Intrusive Load Monitoring

    PubMed Central

    Alcalá, José M.; Ureña, Jesús; Hernández, Álvaro; Gualda, David

    2017-01-01

    The ageing of the population, and their increasing wish of living independently, are motivating the development of welfare and healthcare models. Existing approaches based on the direct heath-monitoring using body sensor networks (BSN) are precise and accurate. Nonetheless, their intrusiveness causes non-acceptance. New approaches seek the indirect monitoring through monitoring activities of daily living (ADLs), which proves to be a suitable solution. ADL monitoring systems use many heterogeneous sensors, are less intrusive, and are less expensive than BSN, however, the deployment and maintenance of wireless sensor networks (WSN) prevent them from a widespread acceptance. In this work, a novel technique to monitor the human activity, based on non-intrusive load monitoring (NILM), is presented. The proposal uses only smart meter data, which leads to minimum intrusiveness and a potential massive deployment at minimal cost. This could be the key to develop sustainable healthcare models for smart homes, capable of complying with the elderly people’ demands. This study also uses the Dempster-Shafer theory to provide a daily score of normality with regard to the regular behavior. This approach has been evaluated using real datasets and, additionally, a benchmarking against a Gaussian mixture model approach is presented. PMID:28208672

  8. Cosmic Ray Energetics And Mass (CREAM) Launch and Operations

    NASA Astrophysics Data System (ADS)

    Seo, Eun-Suk

    We request continued NASA support for the on-going Cosmic Ray Energetics And Mass (CREAM) project. The balloon-borne CREAM instrument was flown for 161 days in six flights over Antarctica, the longest known exposure for a single balloon project. Building on the success of those balloon missions, one of the two balloon payloads was successfully transformed for exposure on the International Space Station (ISS) Japanese Experiment Module Exposed Facility (JEM EF). Following completion of its systemlevel qualification and verification, this ISS-CREAM payload was delivered to the NASA Kennedy Space Center in August 2015 to await its launch to the ISS. The ISS-CREAM mission would achieve the primary science objectives of the Advanced Cosmic-ray Composition Experiment for the Space Station (ACCESS), which was given high priority in the 2001 NRC Decadal Study Report. Its nuclei composition data between 10^12 and 10^15 eV would enable detailed study of the spectral hardening first reported by the CREAM balloon project and recently confirmed for protons and helium by the PAMELA and AMS-02 space missions using permanent magnet spectrometers. In addition, multiTeV energy electron data allow searches for local sources and the signature of darkmatter, etc. The ISS-CREAM instrument is configured with redundant and complementary particle detectors capable of precise measurements of elemental spectra for Z = 1 - 26 nuclei, as well as electrons. The four layers of its finely segmented Silicon Charge Detector provide charge measurements, and its ionization calorimeter provides energy measurements. Its segmented scintillator-based Top and Bottom Counting Detectors separate electrons from nuclei using shower profile differences. Its Boronated Scintillator Detector distinguishes electrons from nuclei by detecting thermal neutrons that are dominant in nuclei induced showers. An order of magnitude increase in data collecting power is possible by utilizing the ISS to reach the highest

  9. ‘ZipperCream-CG’ and ‘WhiteAcre-DG’: Two New Cream-type Southernpea Cultivars with Persistent Green Seed Phenotypes

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Efforts to incorporate genes conditioning a persistent green seed phenotype into ‘Zipper Cream’ and ‘White Acre’ type backgrounds were completed with the official release of the new southernpea (Vigna unguiculata (L.) Walp.) cultivars ZipperCream-CG and WhiteAcre-DG on 29 January 2008. ‘ZipperCream...

  10. Wireless structural health monitoring for critical members of civil infrastructures using piezoelectric active sensors

    NASA Astrophysics Data System (ADS)

    Park, Seunghee; Yun, Chung-Bang; Inman, Daniel J.; Park, Gyuhae

    2008-03-01

    This paper presents several challenging issues on wireless structural health monitoring techniques for critical members of civil infrastructures using piezoelectric active sensors. The basic concept of the techniques is to monitor remotely the structural integrity by observing the impedance variations at the piezoelectric active sensors distributed to critical members of a host structure. An active sensing node incorporating on-board microprocessor and radio frequency telemetry is introduced in a sense of tailoring wireless sensing technology to the impedance method. A data compression algorithm using principal component analysis is embedded into the on-board chip of the active sensing node. The data compression algorithm would promote efficiency in terms of both power management and noise elimination of the active sensor node. Finally, a piezoelectric sensor self-diagnosis issue is touched introducing a new impedance model equation that incorporates the effects of sensor and bonding defects.

  11. Crosswell CASSM(Continuous Active-Source Seismic Monitoring): Recent Developments (Invited)

    NASA Astrophysics Data System (ADS)

    Daley, T. M.; Niu, F.; Ajo Franklin, J. B.; Solbau, R.; Silver, P. G.

    2009-12-01

    Continuous active-source monitoring using borehole sources and sensors in a crosswell configuration has proven to be a useful tool for monitoring subsurface processes (Silver, et al, 2007; Daley, et al, 2007; Niu, et al, 2008). This recent work has focused on two applications: monitoring stress changes related to seismicity and monitoring changes in fluid distribution related to geologic storage of CO2. Field tests have demonstrated precision in travel time measurement of up to 1.1 x 10-7 s, and in velocity perturbation measurement of up to 1.1 x 10-5 (Niu, et al 2008). In this talk I will summarize our preceding work and discuss current developments. Current efforts address both hardware and design challenges to improving the methodology. Hardware issues include deployment of multiple piezoelectric sources in shallow and deep boreholes, source and sensor deployment on tubing inside casing, and deployment with other monitoring instrumentation. Design issues are focused on use of multiple sources and/or sensors to obtain optimal spatial resolution for monitoring processes in the interwell region. This design issue can be investigated with optimal experiment design theory. New field experiments for monitoring seismicity (at SAFOD) and CO2 injection (at a US Dept of Energy pilot) are in the design/deployment stage. Current status of these projects will be discussed. References: Silver, P.G., Daley, T.M., Niu, F., Majer, E.L., 2007, Active source monitoring of crosswell seismic travel time for stress induced changes, Bulletin of Seismological Society of America, v97, n1B, p281-293. Daley, T.M., R.D. Solbau, J.B. Ajo-Franklin, S.M. Benson, 2007, Continuous active-source monitoring of CO2 injection in a brine aquifer, Geophysics, v72, n5, pA57-A61, DOI:10.1190/1.2754716. Niu, F., Silver, P.G., Daley, T.M., Cheng, X., Majer, E.L., 2008, Preseismic velocity changes observed from active source monitoring at the Parkfield SAFOD drill site, Nature, 454, 204-208, DOI:10

  12. Chemical sensor platform for non-invasive monitoring of activity and dehydration.

    PubMed

    Solovei, Dmitry; Žák, Jaromír; Majzlíková, Petra; Sedláček, Jiří; Hubálek, Jaromír

    2015-01-14

    A non-invasive solution for monitoring of the activity and dehydration of organisms is proposed in the work. For this purpose, a wireless standalone chemical sensor platform using two separate measurement techniques has been developed. The first approach for activity monitoring is based on humidity measurement. Our solution uses new humidity sensor based on a nanostructured TiO2 surface for sweat rate monitoring. The second technique is based on monitoring of potassium concentration in urine. High level of potassium concentration denotes clear occurrence of dehydration. Furthermore, a Wireless Body Area Network (WBAN) was developed for this sensor platform to manage data transfer among devices and the internet. The WBAN coordinator controls the sensor devices and collects and stores the measured data. The collected data is particular to individuals and can be shared with physicians, emergency systems or athletes' coaches. Long-time monitoring of activity and potassium concentration in urine can help maintain the appropriate water intake of elderly people or athletes and to send warning signals in the case of near dehydration. The created sensor system was calibrated and tested in laboratory and real conditions as well. The measurement results are discussed.

  13. Pattern of active and inactive sequences of diabetes self-monitoring in mobile phone and paper diary users.

    PubMed

    Padhye, Nikhil S; Jing Wang

    2015-01-01

    In a pilot randomized controlled trial involving overweight or obese participants with type 2 diabetes, we find that smartphone users have sharply higher adherence to self-monitoring of diet, physical activity, blood glucose, and body weight, as compared to paper diary users. By characterizing the pattern of adherence with the probability of continuation of active and inactive sequences of self-monitoring, we find that smartphone users have longer active sequences of self-monitoring of all four behaviors that were being monitored. Smartphone users are also quicker to resume self-monitoring of diet and physical activity after a lapse in self-monitoring, whereas paper diary users have shorter inactive sequences for monitoring blood glucose and body weight. The findings are informative for data collection methodology in this burgeoning area of research.

  14. Geochemical monitoring of thermal waters in Slovenia: relationships to seismic activity.

    PubMed

    Zmazek, B; Italiano, F; Zivcić, M; Vaupotic, J; Kobal, I; Martinelli, G

    2002-12-01

    Thermally anomalous fluids released in seismic areas in Slovenia were the subjects of geochemical monitoring. Thermal waters were surveyed from the seismically active area of Posocje (Bled and Zatolmin; NW Slovenia) and from Rogaska Slatina in eastern Slovenia. Continuous monitoring of geochemical parameters (radon concentration, electrical conductivity, and water temperature) was performed with discrete gas sampling for their (3)He/(4)He ratio. The observed values were correlated with meteorological parameters (rainfall, barometric pressure and air temperature) and with seismic activity. Only a few earthquakes occurred in the vicinity of the measuring sites during the monitoring period. Nevertheless, changes in radon concentration, water temperature, electrical conductivity and helium isotopic ratio were detected at the three thermal springs in the periods preceding the earthquakes. A close correlation was also observed of both water temperature and electrical conductivity with the Earth tide, making the observations in the selected sites a promising tool for addressing the widely debated question of earthquake prediction.

  15. Inventory of non-federally funded marine pollution research, development, and monitoring activities: West Coast region

    SciTech Connect

    Canton, G.M.; Opresko, D.M.; Weaver, R.S.

    1987-12-01

    Knowledge of current marine pollution research and monitoring programs is an important factor in planning and guiding future national efforts to control such pollution. To supplement these reports on Federal activities, NMPPO published a series of reports in 1980 on non-federally funded marine pollution research and monitoring activities in various regions. The following document presents an update of one of these reports. It presents an inventory of the non-federally funded research and monitoring projects for the West Coast region of the United States. It is one in a series of four updates that will collectively provide an updated inventory of non-federally funded projects for all the coastal regions of the United States.

  16. Influence of social connectedness, communication and monitoring on adolescent sexual activity in Ghana.

    PubMed

    Kumi-Kyereme, Akwasi; Awusabo-Asare, Kofi; Biddlecom, Ann; Tanle, Augustine

    2007-12-01

    This paper examines connectedness to, communication with and monitoring of unmarried adolescents in Ghana by parents, other adults, friends and key social institutions and the roles these groups play with respect to adolescent sexual activity. The paper draws on 2004 nationally-representative survey data and qualitative evidence from focus group discussions and in-depth interviews with adolescents in 2003. Adolescents show high levels of connectedness to family, adults, friends, school and religious groups. High levels of adult monitoring are also observed, but communication with family about sex-related matters was not as high as with non-family members. The qualitative data highlight gender differences in communication. Multivariate analysis of survey data shows a strong negative relationship between parental monitoring and recent sexual activity for males and females, and limited effects of communication. Creating a supportive environment and showing interest in the welfare of adolescents appear to promote positive sexual and reproductive health outcomes.

  17. Validity of activity monitors in health and chronic disease: a systematic review

    PubMed Central

    2012-01-01

    The assessment of physical activity in healthy populations and in those with chronic diseases is challenging. The aim of this systematic review was to identify whether available activity monitors (AM) have been appropriately validated for use in assessing physical activity in these groups. Following a systematic literature search we found 134 papers meeting the inclusion criteria; 40 conducted in a field setting (validation against doubly labelled water), 86 in a laboratory setting (validation against a metabolic cart, metabolic chamber) and 8 in a field and laboratory setting. Correlation coefficients between AM outcomes and energy expenditure (EE) by the criterion method (doubly labelled water and metabolic cart/chamber) and percentage mean differences between EE estimation from the monitor and EE measurement by the criterion method were extracted. Random-effects meta-analyses were performed to pool the results across studies where possible. Types of devices were compared using meta-regression analyses. Most validation studies had been performed in healthy adults (n = 118), with few carried out in patients with chronic diseases (n = 16). For total EE, correlation coefficients were statistically significantly lower in uniaxial compared to multisensor devices. For active EE, correlations were slightly but not significantly lower in uniaxial compared to triaxial and multisensor devices. Uniaxial devices tended to underestimate TEE (−12.07 (95%CI; -18.28 to −5.85) %) compared to triaxial (−6.85 (95%CI; -18.20 to 4.49) %, p = 0.37) and were statistically significantly less accurate than multisensor devices (−3.64 (95%CI; -8.97 to 1.70) %, p<0.001). TEE was underestimated during slow walking speeds in 69% of the lab validation studies compared to 37%, 30% and 37% of the studies during intermediate, fast walking speed and running, respectively. The high level of heterogeneity in the validation studies is only partly explained by the type of activity

  18. Irradiated beetroot extract as a colorant for cream cheese

    NASA Astrophysics Data System (ADS)

    Junqueira-Goncalves, Maria Paula; Cardoso, Lediana Pereira; Pinto, Michele Silva; Pereira, Rodrigo Magela; Soares, Nilda Ferreira; Miltz, Joseph

    2011-01-01

    A Brazilian ham-flavored cream cheese was developed using gamma-irradiated beetroot extract as the colorant. An irradiation dose of 5.0 kGy was used based on previous studies that indicated no growth of moulds, yeasts and aerobic psychotropic microorganisms during 12 days at 5 °C, and with no changes in the structure of the pigment. One part of the cheese was colored with the irradiated beetroot extract and the other part with carmine cochineal, which is a natural stable colorant but expensive and difficult to extract. Both portions were submitted to sensory evaluation with 67 panelists. No significant differences were found in flavor and overall appearance. The cream cheese containing carmine cochineal was slightly preferred in regards to color. However, being a new product, these results were encouraging and point towards the potential use of irradiated beetroot extract as a natural food colorant.

  19. Dilutions of corticosteroid creams and ointments - a stability study.

    PubMed

    Cornarakis-Lentzos, M; Cowin, P R

    1987-01-01

    A study was carried out on the stability of dilutions of creams and ointments of two corticosteroids, betamethasone valerate and beclomethasone dipropionate. A reversed-phase high-performance liquid chromatographic method was developed that is simple, efficient and stability-indicating in respect of the main decomposition products and has the advantage of being carried out at ambient temperature. The effect of water content of the sample solutions and the influence of large injection volumes (200-250 mul) on the resolution of the substances on the chromatogram was investigated. Use of the diluents, cetomacrogol cream (formula A) BP and white soft paraffin BP, resulted in satisfactory products in terms of chemical stability and efficacy of antimicrobial preservation.

  20. Cream formulations protecting against cercarial dermatitis by Trichobilharzia.

    PubMed

    Wulff, C; Haeberlein, S; Haas, W

    2007-06-01

    Dermatitis caused by penetrating bird schistosome cercariae is an emerging global public health problem. Infections may be prevented by the use of topical formulations that inhibit cercarial skin penetration. We evaluated nine water resistant formulations by exposing treated arms of volunteers to Trichobilharzia szidati cercariae. Six formulations protected from cercarial invasion. However, after immersion of the treated skin in water (2 x 20 min), only two formulations offered full protection: (1) Safe Sea, a cream protecting against jelly fish, (2) niclosamide in water resistant sun protecting cream formulations at concentrations as low as 0.05%. In an in vitro system Safe Sea and a 0.1% niclosamide formulation caused a high damage rate in T. szidati (92% and 99% after 5 min; only niclosamide with lethal effect) but not in Schistosoma mansoni (1% and 72%; both formulations with lethal effect). However, a 1% niclosamide formulation damaged S. mansoni sufficiently (100% after 5 min) and might offer full penetration protection.

  1. Testing the reliability of ice-cream cone model

    NASA Astrophysics Data System (ADS)

    Pan, Z.; Shen, C.; Wang, Y.; Liu, K.

    2013-12-01

    Coronal Mass Ejections (CME)'s properties are important to not only the physical scene itself but spaceweather prediction. Several models(such as cone model, GCS model, and so on) have been raised to get rid of the projection effects within the properties observated by spacecraft. According to SOHO/ LASCO observations, we obtain the 'real' 3D parameters of 33 FFHCMEs (front-side full halo Coronal Mass Ejections) within the 24th solar cycle by the ice-cream cone model. Considering that the method to obtain 3D parameters from the CME observations by multi-satellite and multi-angle has higher accuracy, we use the GCS model to obtain the real propagation parameters of these CMEs in 3D space and compare the results with which by ice-cream cone model. It was demonstrated that the correlation coefficient for the speeds by using these both methods is 0.97.

  2. ISS-CREAM Thermal and Fluid System Design and Analysis

    NASA Technical Reports Server (NTRS)

    Thorpe, Rosemary S.

    2015-01-01

    Thermal and Fluids Analysis Workshop (TFAWS), Silver Spring MD NCTS 21070-15. The ISS-CREAM (Cosmic Ray Energetics And Mass for the International Space Station) payload is being developed by an international team and will provide significant cosmic ray characterization over a long time frame. Cold fluid provided by the ISS Exposed Facility (EF) is the primary means of cooling for 5 science instruments and over 7 electronics boxes. Thermal fluid integrated design and analysis was performed for CREAM using a Thermal Desktop model. This presentation will provide some specific design and modeling examples from the fluid cooling system, complex SCD (Silicon Charge Detector) and calorimeter hardware, and integrated payload and ISS level modeling. Features of Thermal Desktop such as CAD simplification, meshing of complex hardware, External References (Xrefs), and FloCAD modeling will be discussed.

  3. Terconazole and miconazole cream for treating vulvovaginal candidiasis. A comparison.

    PubMed

    Corson, S L; Kapikian, R R; Nehring, R

    1991-08-01

    In a double-blind, randomized, multicenter study, 900 patients diagnosed with vulvovaginal candidiasis received either 0.4% (307 patients) or 0.8% (299 patients) terconazole cream or 2.0% miconazole nitrate cream (294 patients). After seven days of treatment the combined microbiologic and clinical cure rates were 87.9% for the 0.4% terconazole group, 83.8% for patients treated with 0.8% terconazole and 81.3% for the 2.0% miconazole nitrate group. The microbiologic and clinical cure rates were similarly high. The 0.4% terconazole formulation consistently provided a greater degree of symptom relief and significantly fewer adverse genital-reproductive reactions as compared with 2.0% miconazole nitrate. All three preparations were well tolerated, with only minor adverse reactions; all three seem to be useful for the treatment of vulvovaginal candidiasis.

  4. Infrared imaging spectroscopy and chemometric tools for in situ analysis of an imiquimod pharmaceutical preparation presented as cream

    NASA Astrophysics Data System (ADS)

    Carneiro, Renato Lajarim; Poppi, Ronei Jesus

    2014-01-01

    In the present work the homogeneity of a pharmaceutical formulation presented as a cream was studied using infrared imaging spectroscopy and chemometric methodologies such as principal component analysis (PCA) and multivariate curve resolution with alternating least squares (MCR-ALS). A cream formulation, presented as an emulsion, was prepared using imiquimod as the active pharmaceutical ingredient (API) and the excipients: water, vaseline, an emulsifier and a carboxylic acid in order to dissolve the API. After exposure at 45 °C during 3 months to perform accelerated stability test, the presence of some crystals was observed, indicating homogeneity problems in the formulation. PCA exploratory analysis showed that the crystal composition was different from the composition of the emulsion, since the score maps presented crystal structures in the emulsion. MCR-ALS estimated the spectra of the crystals and the emulsion. The crystals presented amine and C-H bands, suggesting that the precipitate was a salt formed by carboxylic acid and imiquimod. These results indicate the potential of infrared imaging spectroscopy in conjunction with chemometric methodologies as an analytical tool to ensure the quality of cream formulations in the pharmaceutical industry.

  5. Prevention of airway inflammation with topical cream containing imiquimod and small interfering RNA for natriuretic peptide receptor

    PubMed Central

    Wang, Xiaoqin; Xu, Weidong; Mohapatra, Subhra; Kong, Xiaoyuan; Li, Xu; Lockey, Richard F; Mohapatra, Shyam S

    2008-01-01

    Background Asthma is a complex disease, characterized by reversible airway obstruction, hyperresponsiveness and chronic inflammation. Principle pharmacologic treatments for asthma include bronchodilating beta2-agonists and anti-inflammatory glucocorticosteroids; but these agents do not target the main cause of the disease, the generation of pathogenic Th2 cells. We previously reported reduction in allergic inflammation in mice deficient in the ANP receptor NPRA. Here we determined whether siRNA for natriuretic peptide receptor A (siNPRA) protected against asthma when administered transdermally. Methods Imiquimod cream mixed with chitosan nanoparticles containing either siRNA green indicator (siGLO) or siNPRA was applied to the skin of mice. Delivery of siGLO was confirmed by fluorescence microscopy. The anti-inflammatory activity of transdermal siNPRA was tested in OVA-sensitized mice by measuring airway hyperresponsiveness, eosinophilia, lung histopathology and pro-inflammatory cytokines. Results SiGLO appearing in the lung proved the feasibility of transdermal delivery. In a mouse asthma model, BALB/c mice treated with imiquimod cream containing siNPRA chitosan nanoparticles showed significantly reduced airway hyperresponsiveness, eosinophilia, lung histopathology and pro-inflammatory cytokines IL-4 and IL-5 in lung homogenates compared to controls. Conclusion These results demonstrate that topical cream containing imiquimod and siNPRA nanoparticles exerts an anti-inflammatory effect and may provide a new and simple therapy for asthma. PMID:18279512

  6. Optimisation of flavour ester biosynthesis in an aqueous system of coconut cream and fusel oil catalysed by lipase.

    PubMed

    Sun, Jingcan; Yu, Bin; Curran, Philip; Liu, Shao-Quan

    2012-12-15

    Coconut cream and fusel oil, two low-cost natural substances, were used as starting materials for the biosynthesis of flavour-active octanoic acid esters (ethyl-, butyl-, isobutyl- and (iso)amyl octanoate) using lipase Palatase as the biocatalyst. The Taguchi design method was used for the first time to optimize the biosynthesis of esters by a lipase in an aqueous system of coconut cream and fusel oil. Temperature, time and enzyme amount were found to be statistically significant factors and the optimal conditions were determined to be as follows: temperature 30°C, fusel oil concentration 9% (v/w), reaction time 24h, pH 6.2 and enzyme amount 0.26 g. Under the optimised conditions, a yield of 14.25mg/g (based on cream weight) and signal-to-noise (S/N) ratio of 23.07 dB were obtained. The results indicate that the Taguchi design method was an efficient and systematic approach to the optimisation of lipase-catalysed biological processes.

  7. Infrared imaging spectroscopy and chemometric tools for in situ analysis of an imiquimod pharmaceutical preparation presented as cream.

    PubMed

    Carneiro, Renato Lajarim; Poppi, Ronei Jesus

    2014-01-24

    In the present work the homogeneity of a pharmaceutical formulation presented as a cream was studied using infrared imaging spectroscopy and chemometric methodologies such as principal component analysis (PCA) and multivariate curve resolution with alternating least squares (MCR-ALS). A cream formulation, presented as an emulsion, was prepared using imiquimod as the active pharmaceutical ingredient (API) and the excipients: water, vaseline, an emulsifier and a carboxylic acid in order to dissolve the API. After exposure at 45°C during 3 months to perform accelerated stability test, the presence of some crystals was observed, indicating homogeneity problems in the formulation. PCA exploratory analysis showed that the crystal composition was different from the composition of the emulsion, since the score maps presented crystal structures in the emulsion. MCR-ALS estimated the spectra of the crystals and the emulsion. The crystals presented amine and C-H bands, suggesting that the precipitate was a salt formed by carboxylic acid and imiquimod. These results indicate the potential of infrared imaging spectroscopy in conjunction with chemometric methodologies as an analytical tool to ensure the quality of cream formulations in the pharmaceutical industry.

  8. Activity Learning as a Foundation for Security Monitoring in Smart Homes.

    PubMed

    Dahmen, Jessamyn; Thomas, Brian L; Cook, Diane J; Wang, Xiaobo

    2017-03-31

    Smart environment technology has matured to the point where it is regularly used in everyday homes as well as research labs. With this maturation of the technology, we can consider using smart homes as a practical mechanism for improving home security. In this paper, we introduce an activity-aware approach to security monitoring and threat detection in smart homes. We describe our approach using the CASAS smart home framework and activity learning algorithms. By monitoring for activity-based anomalies we can detect possible threats and take appropriate action. We evaluate our proposed method using data collected in CASAS smart homes and demonstrate the partnership between activity-aware smart homes and biometric devices in the context of the CASAS on-campus smart apartment testbed.

  9. [Successful symptomatic treatment of epidermodysplasia verruciformis with imiquimod 5% cream].

    PubMed

    Heratizadeh, A; Völker, B; Kupsch, E; Wichmann, K; Kapp, A; Werfel, T

    2010-12-01

    A 19-year-old patient presented with epidermodysplasia verruciformis (EV). In this genodermatosis, pathogenetic factors such as infection by human papilloma viruses as well as sun exposure are considered responsible for the malignant transformation of EV lesions to skin cancer within decades. So far, several therapeutic strategies have been unsatisfactory. In our case HPV 5b was detected and the associated skin lesions were successfully treated with imiquimod 5% cream.

  10. Cream formulation impact on topical administration of engineered colloidal nanoparticles.

    PubMed

    Santini, Benedetta; Zanoni, Ivan; Marzi, Roberta; Cigni, Clara; Bedoni, Marzia; Gramatica, Furio; Palugan, Luca; Corsi, Fabio; Granucci, Francesca; Colombo, Miriam

    2015-01-01

    In order to minimize the impact of systemic toxicity of drugs in the treatment of local acute and chronic inflammatory reactions, the achievement of reliable and efficient delivery of therapeutics in/through the skin is highly recommended. While the use of nanoparticles is now an established practice for drug intravenous targeted delivery, their transdermal penetration is still poorly understood and this important administration route remains almost unexplored. In the present study, we have synthesized magnetic (iron oxide) nanoparticles (MNP) coated with an amphiphilic polymer, developed a water-in-oil emulsion formulation for their topical administration and compared the skin penetration routes with the same nanoparticles deposited as a colloidal suspension. Transmission and scanning electron microscopies provided ultrastructural evidence that the amphiphilic nanoparticles (PMNP) cream formulation allowed the efficient penetration through all the skin layers with a controllable kinetics compared to suspension formulation. In addition to the preferential follicular pathway, also the intracellular and intercellular routes were involved. PMNP that crossed all skin layers were quantified by inductively coupled plasma mass spectrometry. The obtained data suggests that combining PMNP amphiphilic character with cream formulation improves the intradermal penetration of nanoparticles. While PMNP administration in living mice via aqueous suspension resulted in preferential nanoparticle capture by phagocytes and migration to draining lymph nodes, cream formulation favored uptake by all the analyzed dermis cell types, including hematopoietic and non-hematopoietic. Unlike aqueous suspension, cream formulation also favored the maintenance of nanoparticles in the dermal architecture avoiding their dispersion and migration to draining lymph nodes via afferent lymphatics.

  11. Cream Formulation Impact on Topical Administration of Engineered Colloidal Nanoparticles

    PubMed Central

    Marzi, Roberta; Cigni, Clara; Bedoni, Marzia; Gramatica, Furio; Palugan, Luca; Corsi, Fabio; Granucci, Francesca; Colombo, Miriam

    2015-01-01

    In order to minimize the impact of systemic toxicity of drugs in the treatment of local acute and chronic inflammatory reactions, the achievement of reliable and efficient delivery of therapeutics in/through the skin is highly recommended. While the use of nanoparticles is now an established practice for drug intravenous targeted delivery, their transdermal penetration is still poorly understood and this important administration route remains almost unexplored. In the present study, we have synthesized magnetic (iron oxide) nanoparticles (MNP) coated with an amphiphilic polymer, developed a water-in-oil emulsion formulation for their topical administration and compared the skin penetration routes with the same nanoparticles deposited as a colloidal suspension. Transmission and scanning electron microscopies provided ultrastructural evidence that the amphiphilic nanoparticles (PMNP) cream formulation allowed the efficient penetration through all the skin layers with a controllable kinetics compared to suspension formulation. In addition to the preferential follicular pathway, also the intracellular and intercellular routes were involved. PMNP that crossed all skin layers were quantified by inductively coupled plasma mass spectrometry. The obtained data suggests that combining PMNP amphiphilic character with cream formulation improves the intradermal penetration of nanoparticles. While PMNP administration in living mice via aqueous suspension resulted in preferential nanoparticle capture by phagocytes and migration to draining lymph nodes, cream formulation favored uptake by all the analyzed dermis cell types, including hematopoietic and non-hematopoietic. Unlike aqueous suspension, cream formulation also favored the maintenance of nanoparticles in the dermal architecture avoiding their dispersion and migration to draining lymph nodes via afferent lymphatics. PMID:25962161

  12. Formulation of creams with betamethasone dipropionate: evaluation of chemical stability.

    PubMed

    Băiţan, Mariana; Gafiţanu, Eliza; Lionte, Mihaela; Moisuc, Lăcrămioara

    2010-01-01

    The aim of this study was to investigate how the different excipients influenced the chemical stability of betamethasone dipropionate in creams. The chemical stability was evaluated by analyzing betamethasone related substance content. Transcutol is the excipient ensuring maximum stability to betamethasone. Incompatibilities between betamethasone dipropionate and hexylene glycol were observed. The pH values in the weak acid range confer chemical stability to betamethasone.

  13. The Activation and Monitoring of Memories Produced by Words and Pseudohomophones

    ERIC Educational Resources Information Center

    Cortese, Michael J.; Khanna, Maya M.; White, Katherine K.; Veljkovic, Ilija; Drumm, Geoffery

    2008-01-01

    Using the DRM paradigm, our experiments examined the activation and monitoring of memories in semantic and phonological networks. Participants viewed lists of words and/or pseudohomophones (e.g., "dreem"). In Experiment 1, participants verbally recalled lists of semantic associates or attempted to write them as they appeared during study. False…

  14. 14 CFR 405.1 - Monitoring of licensed, permitted, and other activities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Monitoring of licensed, permitted, and other activities. 405.1 Section 405.1 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL... manufacturing, production, testing, and training facilities, or assembly sites used by any contractor,...

  15. Monitoring Phospholipase A2 Activity with Gd-encapsulated Phospholipid Liposomes

    PubMed Central

    Cheng, Zhiliang; Tsourkas, Andrew

    2014-01-01

    To date, numerous analytical methods have been developed to monitor phospholipase A2 (PLA2) activity. However, many of these methods require the use of unnatural PLA2 substrates that may alter enzyme kinetics, and probes that cannot be extended to applications in more complex environments. It would be desirable to develop a versatile assay that monitors PLA2 activity based on interactions with natural phospholipids in complex biological samples. Here, we developed an activatable T1 magnetic resonance (MR) imaging contrast agent to monitor PLA2 activity. Specifically, the clinically approved gadolinium (Gd)-based MR contrast agent, gadoteridol, was encapsulated within nanometer-sized phospholipid liposomes. The encapsulated Gd exhibited a low T1-weighted signal, due to low membrane permeability. However, when the phospholipids within the liposomal membrane were hydrolyzed by PLA2, encapsulated Gd was released into bulk solution, resulting in a measureable change in the T1-relaxation time. These activatable MR contrast agents can potentially be used as nanosensors for monitoring of PLA2 activity in biological samples with minimal sample preparation. PMID:25376186

  16. IDEA Fiscal Monitoring and Support Activities 2011-2012 Quick Reference Document

    ERIC Educational Resources Information Center

    Regional Resource Center Program, 2011

    2011-01-01

    This Quick Reference Document is being distributed by the Regional Resource Center Program ARRA/Fiscal Priority Team to provide RRCP state liaisons and other (Technical Assistance) TA providers with a summary of critical fiscal monitoring and support activities they may be involved in during calendar years 2011 and 2012. Like other documents in…

  17. GREENHOUSE GAS (GHG) MITIGATION AND MONITORING TECHNOLOGY PERFORMANCE: ACTIVITIES OF THE GHG TECHNOLOGY VERIFICATION CENTER

    EPA Science Inventory

    The paper discusses greenhouse gas (GHG) mitigation and monitoring technology performance activities of the GHG Technology Verification Center. The Center is a public/private partnership between Southern Research Institute and the U.S. EPA's Office of Research and Development. It...

  18. Employing Magnetic Levitation to Monitor Reaction Kinetics and Measure Activation Energy

    ERIC Educational Resources Information Center

    Benz, Lauren; Cesafsky, Karen E.; Le, Tran; Park, Aileen; Malicky, David

    2012-01-01

    This article describes a simple and inexpensive undergraduate-level kinetics experiment that uses magnetic levitation to monitor the progress and determine the activation energy of a condensation reaction on a polymeric solid support. The method employs a cuvette filled with a paramagnetic solution positioned between two strong magnets. The…

  19. DEVELOPMENT OF AN ETD SURVEILLANCE CHECKLIST FOR MONITORING EPA RESEARCH ACTIVITIES

    EPA Science Inventory

    DEVELOPMENT OF AN ETD SURVEILLANCE CHECKLIST FOR MONITORING EPA RESEARCH ACTIVITIES, Thomas J. Hughes, National Health and Environmental Effects Research Laboratory (NHEERL), ORD, U.S. EPA, Experimental Toxicology Division (ETD), MD 66, RTP, NC 27711

    Research studies condu...

  20. Physical Activity Monitoring: Gadgets and Uses. Article #6 in a 6-Part Series

    ERIC Educational Resources Information Center

    Mears, Derrick

    2010-01-01

    An early 15th century drawing by Leonardo da Vinci depicted a device that used gears and a pendulum that moved in synchronization with the wearer as he or she walked. This is believed to be the early origins of today's physical activity monitoring devices. Today's devices have vastly expanded on da Vinci's ancient concept with a myriad of options…

  1. 14 CFR 405.1 - Monitoring of licensed, permitted, and other activities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Monitoring of licensed, permitted, and other activities. 405.1 Section 405.1 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURE INVESTIGATIONS AND ENFORCEMENT §...

  2. 14 CFR 405.1 - Monitoring of licensed, permitted, and other activities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Monitoring of licensed, permitted, and other activities. 405.1 Section 405.1 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURE INVESTIGATIONS AND ENFORCEMENT §...

  3. 14 CFR 405.1 - Monitoring of licensed, permitted, and other activities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Monitoring of licensed, permitted, and other activities. 405.1 Section 405.1 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURE INVESTIGATIONS AND ENFORCEMENT §...

  4. 14 CFR 405.1 - Monitoring of licensed, permitted, and other activities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Monitoring of licensed, permitted, and other activities. 405.1 Section 405.1 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURE INVESTIGATIONS AND ENFORCEMENT §...

  5. OLAM: A wearable, non-contact sensor for continuous heart-rate and activity monitoring.

    PubMed

    Albright, Ryan K; Goska, Benjamin J; Hagen, Tory M; Chi, Mike Y; Cauwenberghs, G; Chiang, Patrick Y

    2011-01-01

    A wearable, multi-modal sensor is presented that can non-invasively monitor a patient's activity level and heart function concurrently for more than a week. The 4 in(2) sensor incorporates both a non-contact heartrate sensor and a 5-axis inertial measurement unit (IMU), allowing simultaneous heart, respiration, and movement monitoring without requiring physical contact with the skin [1]. Hence, this Oregon State University Life and Activity Monitor (OLAM) provides the unique opportunity to combine motion data with heart-rate information, enabling assessment of actual physical activity beyond conventional movement sensors. OLAM also provides a unique platform for non-contact sensing, enabling the filtering of movement artifacts generated by the non-contact capacitive interface, using the IMU data as a movement noise channel. Intended to be used in clinical trials for weeks at a time with no physician intervention, the OLAM allows continuous non-invasive monitoring of patients, providing the opportunity for long-term observation into a patient's physical activity and subtle longitudinal changes.

  6. Exercise Therapy for Management of Type 2 Diabetes Mellitus: Superior Efficacy of Activity Monitors over Pedometers

    PubMed Central

    Umezono, Tomoya; Fukagawa, Masafumi

    2016-01-01

    We compared the efficacy of activity monitor (which displays exercise intensity and number of steps) versus that of pedometer in exercise therapy for patients with type 2 diabetes. The study subjects were divided into the activity monitor group (n = 92) and pedometer group (n = 95). The primary goal was improvement in hemoglobin A1c (HbA1c). The exercise target was set at 8,000 steps/day and 20 minutes of moderate-intensity exercise (≥3.5 metabolic equivalents). The activity monitor is equipped with a triple-axis accelerometer sensor capable of measuring medium-intensity walking duration, number of steps, walking distance, calorie consumption, and total calorie consumption. The pedometer counts the number of steps. Blood samples for laboratory tests were obtained during the visits. The first examination was conducted at the start of the study and repeated at 2 and 6 months. A significant difference in the decrease in HbA1c level was observed between the two groups at 2 months. The results suggest that the use of activity level monitor that displays information on exercise intensity, in addition to the number of steps, is useful in exercise therapy as it enhances the concept of exercise therapy and promotes lowering of HbA1c in diabetic patients. PMID:27761471

  7. Determining Daily Physical Activity Levels of Youth with Developmental Disabilities: Days of Monitoring Required?

    ERIC Educational Resources Information Center

    Kim, So-Yeun; Yun, Joonkoo

    2009-01-01

    This study examined sources of variability in physical activity (PA) of youth with developmental disabilities (DD), and determined the optimal number of days required for monitoring PA. Sixteen youth with DD wore two pedometers and two accelerometers for 9 days, including 5 weekdays (W) and 2 weekends (WK). A two-facet in fully crossed two-way…

  8. Small Schools Mathematics Curriculum, 9-12: Scope Objectives, Activities, Resources, Monitoring Procedures.

    ERIC Educational Resources Information Center

    Nelson, JoAnne, Ed.; And Others

    The grade 9-12 mathematics curriculum learning objectives, activities, monitoring procedures and resources for small schools were developed during 1978-79 through the cooperative efforts of 10 Snohomish and Island County school districts, Educational Service District 189 and the Washington State Office of Public Instruction. The objectives were…

  9. 30 CFR 280.29 - Will MMS monitor the environmental effects of my activity?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Will MMS monitor the environmental effects of my activity? 280.29 Section 280.29 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE PROSPECTING FOR MINERALS OTHER THAN OIL, GAS,...

  10. Reciprocal Teaching of Comprehension-Monitoring Activities. Technical Report No. 269.

    ERIC Educational Resources Information Center

    Palincsar, Annemarie Sullivan; Brown, Ann L.

    Three studies were conducted to test the effectiveness of reciprocal teaching as a means of instructing seventh grade poor readers about activities they could use to increase comprehension and to ascertain that their comprehension was proceeding smoothly (comprehension monitoring). Reciprocal teaching involves having teacher and students take…

  11. Quality assurance project plan for ground water monitoring activities managed by Westinghouse Hanford Company. Revision 3

    SciTech Connect

    Stauffer, M.

    1995-11-01

    This quality assurance project plan (QAPP) applies specifically to the field activities and laboratory analysis performed for all RCRA groundwater projects conducted by Hanford Technical Services. This QAPP is generic in approach and shall be implemented in conjunction with the specific requirements of individual groundwater monitoring plans.

  12. Functional properties of cholesterol-removed whipping cream treated by beta-cyclodextrin.

    PubMed

    Shim, S Y; Ahn, J; Kwak, H S

    2003-09-01

    The present study was carried out to examine the changes in functional properties of cholesterol-removed whipping cream by beta-cyclodextrin (beta-CD) treatment. The cholesterol removal rate reached over 90% in cream before whipping in all conditions (different stirring time and speed) applied. The apparent viscosity of beta-CD treated cream after whipping increased with increased stirring time and speed. Comparatively, the overrun percentage reached to 150%, and foam instability was measured as 2.5 ml deformed cream with lower stirring time (10 min) and speed (400 rpm). The thiobarbituric acid value of cholesterol-removed whipping cream increased from 0.08 to 0.14 stored at 4 degrees C during 4 wk; however, no difference was found compared with that of control. Above results indicated that beta-CD treatment process for cholesterol removal did not show a profound adverse effect on functional properties of cream after whipping.

  13. Physical and Sensory Properties of Ice Cream Containing Fermented Pepper Powder.

    PubMed

    Yeon, Su-Jung; Kim, Ji-Han; Hong, Go-Eun; Park, Woojoon; Kim, Soo-Ki; Seo, Han-Geuk; Lee, Chi-Ho

    2017-01-01

    This study was conducted to investigate the physical and sensory properties of ice cream containing fermented pepper powder. Three ice cream formulas were manufactured: 1, control; 2, supplemented with 0.1% fermented pepper powder; and 3, supplemented with 0.2% fermented pepper powder. Formulas 2 and 3 had significantly higher viscosity and lower overrun than formula 1 (p<0.05). Additionally, ice creams supplemented with fermented pepper powder were harder and maintained their forms longer than the controls. 0.2% fermented pepper powder added ice cream had no pungency as much as that of control and overall sensory attribute was not significantly different from control. Therefore, ice cream containing fermented pepper powder maintained physical and sensory properties similar to the controls, and maintenance was better. It means fermented pepper powder ice cream can be utilized as the material of functional food (dessert).

  14. The effect of gum tragacanth on the rheological properties of salep based ice cream mix.

    PubMed

    Kurt, Abdullah; Cengiz, Alime; Kahyaoglu, Talip

    2016-06-05

    The influence of concentration (0-0.5%, w/w) of gum tragacanth (GT) on thixotropy, dynamic, and creep-recovery rheological properties of ice cream mixes prepared with milk or water based were investigated. These properties were used to evaluate the viscoelastic behavior and internal structure of ice cream network. The textural properties of ice cream were also evaluated. Thixotropy values of samples were reduced by increasing GT concentration. The dynamic and creep-recovery analyses exhibited that GT addition increased both ice cream elastic and viscous behaviors. The increasing of Burger's model parameters with GT concentration indicated higher resistance network to the stress and more elastic behavior of samples. The applying of Cox-Merz rule is possible by using shift factor (α). GT also led to an increase in Young's modulus and the stickiness of ice creams. The obtained results highlighted the possible application of GT as a valuable member to promote structural properties of ice cream.

  15. Physical and Sensory Properties of Ice Cream Containing Fermented Pepper Powder

    PubMed Central

    Kim, Soo-Ki; Seo, Han-Geuk

    2017-01-01

    This study was conducted to investigate the physical and sensory properties of ice cream containing fermented pepper powder. Three ice cream formulas were manufactured: 1, control; 2, supplemented with 0.1% fermented pepper powder; and 3, supplemented with 0.2% fermented pepper powder. Formulas 2 and 3 had significantly higher viscosity and lower overrun than formula 1 (p<0.05). Additionally, ice creams supplemented with fermented pepper powder were harder and maintained their forms longer than the controls. 0.2% fermented pepper powder added ice cream had no pungency as much as that of control and overall sensory attribute was not significantly different from control. Therefore, ice cream containing fermented pepper powder maintained physical and sensory properties similar to the controls, and maintenance was better. It means fermented pepper powder ice cream can be utilized as the material of functional food (dessert). PMID:28316469

  16. High-throughput metabarcoding of eukaryotic diversity for environmental monitoring of offshore oil-drilling activities.

    PubMed

    Lanzén, Anders; Lekang, Katrine; Jonassen, Inge; Thompson, Eric M; Troedsson, Christofer

    2016-09-01

    As global exploitation of available resources increases, operations extend towards sensitive and previously protected ecosystems. It is important to monitor such areas in order to detect, understand and remediate environmental responses to stressors. The natural heterogeneity and complexity of communities means that accurate monitoring requires high resolution, both temporally and spatially, as well as more complete assessments of taxa. Increased resolution and taxonomic coverage is economically challenging using current microscopy-based monitoring practices. Alternatively, DNA sequencing-based methods have been suggested for cost-efficient monitoring, offering additional insights into ecosystem function and disturbance. Here, we applied DNA metabarcoding of eukaryotic communities in marine sediments, in areas of offshore drilling on the Norwegian continental shelf. Forty-five samples, collected from seven drilling sites in the Troll/Oseberg region, were assessed, using the small subunit ribosomal RNA gene as a taxonomic marker. In agreement with results based on classical morphology-based monitoring, we were able to identify changes in sediment communities surrounding oil platforms. In addition to overall changes in community structure, we identified several potential indicator taxa, responding to pollutants associated with drilling fluids. These included the metazoan orders Macrodasyida, Macrostomida and Ceriantharia, as well as several ciliates and other protist taxa, typically not targeted by environmental monitoring programmes. Analysis of a co-occurrence network to study the distribution of taxa across samples provided a framework for better understanding the impact of anthropogenic activities on the benthic food web, generating novel, testable hypotheses of trophic interactions structuring benthic communities.

  17. CREAM: High Energy Frontier of Cosmic Ray Elemental Spectra

    NASA Astrophysics Data System (ADS)

    Seo, Eun-Suk

    The balloon-borne Cosmic Ray Energetics And Mass (CREAM) experiment was flown for 161 days in six flights over Antarctica. High energy cosmic-ray data were collected over a wide energy range from 10 (10) to 10 (15) eV at an average altitude of 38.5 km with 3.9 g/cm (2) atmospheric overburden. Cosmic-ray elements from protons (Z = 1) to iron nuclei (Z = 26) are separated with excellent charge resolution. Building on success of the balloon flights, the payload is being reconfigured for exposure on the International Space Station (ISS). This ISS-CREAM instrument is configured with the CREAM calorimeter for energy measurements, and four finely segmented Silicon Charge Detector layers for precise charge measurements. In addition, the Top and Bottom Counting Detectors (TCD and BCD) and Boronated Scintillator Detector (BSD) have been newly developed. The TCD and BCD are scintillator based segmented detectors to separate electrons from nuclei using the shower profile differences, while BSD distinguishes electrons from nuclei by detecting thermal neutrons that are dominant in nuclei induced showers. An order of magnitude increase in data collecting power is possible by utilizing the ISS to reach the highest energies practical with direct measurements. The project status including results from on-going analysis of existing data and future plans will be discussed.

  18. Adolescent Substance Use with Friends: Moderating and Mediating Effects of Parental Monitoring and Peer Activity Contexts

    PubMed Central

    Kiesner, Jeff; Poulin, François; Dishion, Thomas J.

    2010-01-01

    The influence of using substances with friends on future individual use was examined in the context of parental monitoring rules and the ecology of peer activities. A one-year longitudinal study design included a combined sample of North Italian and French Canadian adolescents (N = 285, 53% girls, M = 14.25 years). Data analyses were conducted using structural equation modeling and multiple regression analyses. As expected, the covariation between parental monitoring and adolescent substance use was mediated by “co-use” with friends. Moreover, the relation between substance use with friends and individual substance use was moderated by parental monitoring rules and the peer activity context. Specifically, the relation between substance co-use with friends and individual substance use was stronger when the level of parental monitoring rules was low and when friends spent their time together primarily in unstructured contexts such as on the street or in park settings. These findings underline the importance of adults’ use of rules to monitor adolescents prone to substance use, and the role of context in facilitating or reducing peer influence. PMID:21165170

  19. Application of an optimized flow cytometry-based quantification of Platelet Activation (PACT): Monitoring platelet activation in platelet concentrates

    PubMed Central

    Roest, Mark; Henskens, Yvonne M. C.; de Laat, Bas; Huskens, Dana

    2017-01-01

    Background Previous studies have shown that flow cytometry is a reliable test to quantify platelet function in stored platelet concentrates (PC). It is thought that flow cytometry is laborious and hence expensive. We have optimized the flow cytometry-based quantification of agonist induced platelet activation (PACT) to a labor, time and more cost-efficient test. Currently the quality of PCs is only monitored by visual inspection, because available assays are unreliable or too laborious for use in a clinical transfusion laboratory. Therefore, the PACT was applied to monitor PC activation during storage. Study design and methods The optimized PACT was used to monitor 5 PCs during 10 days of storage. In brief, optimized PACT uses a ready-to-use reaction mix, which is stable at -20°C. When needed, a test strip is thawed and platelet activation is initiated by mixing PC with PACT. PACT was based on the following agonists: adenosine diphosphate (ADP), collagen-related peptide (CRP) and thrombin receptor-activating peptide (TRAP-6). Platelet activation was measured as P-selectin expression. Light transmission aggregometry (LTA) was performed as a reference. Results Both PACT and LTA showed platelet function decline during 10-day storage after stimulation with ADP and collagen/CRP; furthermore, PACT showed decreasing TRAP-induced activation. Major differences between the two tests are that PACT is able to measure the status of platelets in the absence of agonists, and it can differentiate between the number of activated platelets and the amount of activation, whereas LTA only measures aggregation in response to an agonist. Also, PACT is more time-efficient compared to LTA and allows high-throughput analysis. Conclusion PACT is an optimized platelet function test that can be used to monitor the activation of PCs. PACT has the same accuracy as LTA with regard to monitoring PCs, but it is superior to both LTA and conventional flow cytometry based tests with regard to labor

  20. Devices for Self-Monitoring Sedentary Time or Physical Activity: A Scoping Review

    PubMed Central

    Loveday, Adam; Pearson, Natalie; Edwardson, Charlotte; Yates, Thomas; Biddle, Stuart JH; Esliger, Dale W

    2016-01-01

    Background It is well documented that meeting the guideline levels (150 minutes per week) of moderate-to-vigorous physical activity (PA) is protective against chronic disease. Conversely, emerging evidence indicates the deleterious effects of prolonged sitting. Therefore, there is a need to change both behaviors. Self-monitoring of behavior is one of the most robust behavior-change techniques available. The growing number of technologies in the consumer electronics sector provides a unique opportunity for individuals to self-monitor their behavior. Objective The aim of this study is to review the characteristics and measurement properties of currently available self-monitoring devices for sedentary time and/or PA. Methods To identify technologies, four scientific databases were systematically searched using key terms related to behavior, measurement, and population. Articles published through October 2015 were identified. To identify technologies from the consumer electronic sector, systematic searches of three Internet search engines were also performed through to October 1, 2015. Results The initial database searches identified 46 devices and the Internet search engines identified 100 devices yielding a total of 146 technologies. Of these, 64 were further removed because they were currently unavailable for purchase or there was no evidence that they were designed for, had been used in, or could readily be modified for self-monitoring purposes. The remaining 82 technologies were included in this review (73 devices self-monitored PA, 9 devices self-monitored sedentary time). Of the 82 devices included, this review identified no published articles in which these devices were used for the purpose of self-monitoring PA and/or sedentary behavior; however, a number of technologies were found via Internet searches that matched the criteria for self-monitoring and provided immediate feedback on PA (ActiGraph Link, Microsoft Band, and Garmin Vivofit) and sedentary time

  1. An analysis of at-home demand for ice cream in the United States.

    PubMed

    Davis, C G; Blayney, D P; Yen, S T; Cooper, J

    2009-12-01

    Ice cream has been manufactured commercially in the United States since the middle of the 19th century. Ice cream and frozen dessert products comprise an important and relatively stable component of the United States dairy industry. As with many other dairy products, ice cream is differentiated in several dimensions. A censored translog demand system model was employed to analyze purchases of 3 ice cream product categories. The objective of this study was to determine the effect that changes in retail prices and consumer income have on at-home ice cream consumption. The analysis was based on Nielsen 2005 home scan retail data and used marital status, age, race, education, female employment status, and location in the estimations of aggregate demand elasticities. Results revealed that price and consumer income were the main determinants of demand for ice cream products. Calculated own-price elasticities indicated relatively elastic responses by consumers for all categories except for compensated bulk ice cream. All expenditure elasticities were inelastic except for bulk ice cream, and most of the ice cream categories were substitutes. Ongoing efforts to examine consumer demand for these products will assist milk producers, dairy processors and manufacturers, and dairy marketers as they face changing consumer responses to food and diet issues.

  2. Cost-effective and monitoring-active technique for TDM-passive optical networks

    NASA Astrophysics Data System (ADS)

    Chi, Chang-Chia; Lin, Hong-Mao; Tarn, Chen-Wen; Lin, Huang-Liang

    2014-08-01

    A reliable, detection-active and cost-effective method which employs the hello and heartbeat signals for branched node distinguishing to monitor fiber fault in any branch of distribution fibers of a time division multiplexing passive optical network (TDM-PON) is proposed. With this method, the material cost of building an optical network monitor system for a TDM-PON with 168 ONUs and the time of identifying a multiple branch faults is significantly reduced in a TDM-PON system of any scale. A fault location in a 1 × 32 TDM-PON system using this method to identify the fault branch is demonstrated.

  3. Scour monitoring system of subsea pipeline using distributed Brillouin optical sensors based on active thermometry

    NASA Astrophysics Data System (ADS)

    Zhao, Xue-Feng; Li, Le; Ba, Qin; Ou, Jin-Ping

    2012-10-01

    A scour monitoring system of subsea pipeline is proposed using distributed Brillouin optical sensors based on active thermometry. The system consists in a thermal cable running parallel to the pipeline, which acquires frequency shift of optical sensors during heating and cooling, directly indicating temperature change. The free spans can be detected through the different behaviors of heat transfer between in-water and in-sediment scenarios. Three features were extracted from temperature time histories including magnitude, spatial continuity and temporal stability. Several experimental tests were conducted using the proposed system. The results substantiate the monitoring technique.

  4. Monitoring activities of daily living based on wearable wireless body sensor network.

    PubMed

    Kańtoch, E; Augustyniak, P; Markiewicz, M; Prusak, D

    2014-01-01

    With recent advances in microprocessor chip technology, wireless communication, and biomedical engineering it is possible to develop miniaturized ubiquitous health monitoring devices that are capable of recording physiological and movement signals during daily life activities. The aim of the research is to implement and test the prototype of health monitoring system. The system consists of the body central unit with Bluetooth module and wearable sensors: the custom-designed ECG sensor, the temperature sensor, the skin humidity sensor and accelerometers placed on the human body or integrated with clothes and a network gateway to forward data to a remote medical server. The system includes custom-designed transmission protocol and remote web-based graphical user interface for remote real time data analysis. Experimental results for a group of humans who performed various activities (eg. working, running, etc.) showed maximum 5% absolute error compared to certified medical devices. The results are promising and indicate that developed wireless wearable monitoring system faces challenges of multi-sensor human health monitoring during performing daily activities and opens new opportunities in developing novel healthcare services.

  5. Efficiency of terbinafine 1% cream in comparison with ketoconazole 2% cream and placebo in patients with facial seborrheic dermatitis.

    PubMed

    Azimi, Hamideh; Golforoushan, Farideh; Jaberian, Mahnaz; Talghini, Shhla; Goldust, Mohamad

    2013-06-06

    Objective: Different medicines have been used to treat seborrheic dermatitis but efficiency of most of them has not been confirmed. This study compared the efficiency of terbinafine 1% cream in comparison with ketoconazole 2% cream and placebo in patients with facial seborrheic dermatitis. Methods: Ninety patients were randomly divided into three groups (there were 30 persons in each group). The patients consumed one of the medicines twice a day and for 4 weeks. The scores were recorded at the trial beginning, and in the 4th and 12th weeks. Demographic features and disease severity of all three groups were normal at the beginning of the study. Results: Mean of total score in terbinafine, ketoconazole and placebo groups was decreased from 5.04 ± 2.02, 5.04 ± 1.50 and 4.97 ± 1.71 at the beginning of the study to 1.78 ± 2.47, 1.81 ± 2.43 and 3.73 ± 1.74 at the 12th week. As compared with the placebo group, mean total score significantly decreased in ketoconazole and terbinafine groups (p = 0.003). However, there was not any meaningful difference between ketoconazole and terbinafine groups (p > 0.05). There was not any serious side effect and the recurrence rate and side effects was not meaningfully different in all three groups. Conclusion: Terbinafine 1% and ketoconazole 2% creams are safe and effective in treating seborrheic dermatitis.

  6. THORON-SCOUT - first diffusion based active Radon and Thoron monitor

    NASA Astrophysics Data System (ADS)

    Wagner, W.; Streil, T.; Oeser, V.; Horak, G.; Duzynski, M.

    2016-10-01

    THORON-SCOUT is a stand-alone diffusion based active Radon and Thoron monitor for long term indoor measurements to evaluate the human health risk due to activity concentration in the breathing air. Alpha-particle spectroscopy of Po isotopes, being the progeny of the decay of the radioactive noble gas Radon, is applied to separately monitor activity contributions of 222Rn and 220Rn (Thoron) as well. In this work we show that the portion of Thoron (Tn) may locally be remarkable and even dominating and cannot be neglected as often has been assumed up to now. Along with tobacco consumption, Rn radioactivity turned out to be a dangerous cause of lung cancer, especially in older badly vented buildings situated in regions of radioactive geological formations. THORON-SCOUT allows a precise examination of the indoor atmosphere with respect to Rn and Inactivity concentration and, therefore, a realistic evaluation of corresponding health risk.

  7. Monitoring the Stellar Activity of Transit-Hosting Stars II: supporting HST exoplanet atmosphere observations

    NASA Astrophysics Data System (ADS)

    Wilson, Paul Anthony; Evans, Tom; Sing, David K.; Aigrain, Suzanne

    2012-02-01

    We propose to use the CTIO 1.3m telescope with ANDICAM to monitor 5 bright stars that host transiting exoplanets in an effort to characterise their activity. These observations will provide critical ground-based support for our large HST program that has been granted 124 orbits to perform a survey of UV-optical atmospheric transmission spectra for 8 hot Jupiters using the STIS instrument (Cycle 19, Prog 12473, PI D Sing). They are required because active stellar regions inevitably contaminate measured planetary light curves by causing the apparent planet-to-star radius to vary in a wavelength dependent manner. Regular ground-based photometric monitoring performed using the CTIO 1.3m telescope will allow us to determine the spot activity at the time of the HST observations, so that the stellar baseline flux can be accurately normalised for every transit observed, enabling transmission spectra from multiple visits to be combined.

  8. Using modalmetric fiber optic sensors to monitor the activity of the heart

    NASA Astrophysics Data System (ADS)

    Życzkowski, M.; Uzięblo-Zyczkowska, B.; Dziuda, L.; Różanowski, K.

    2011-03-01

    The paper presents the concept of the modalmetric fiber optic sensor system for human psychophysical activity detection. A fiber optic sensor that utilizes intensity of propagated light to monitor a patient's vital signs such as respiration cardiac activity, blood pressure and body's physical movements. The sensor, which is non-invasive, comprises an multimode fiber proximately situated to the patient so that time varying acusto-mechanical signals from the patient are coupled by the singlemode optical fiber to detector. The system can be implemented in embodiments ranging form a low cost in-home to a high end product for in hospital use. We present the laboratory test of comparing their results with the known methods like EKG. addition, the article describes the work on integrated system to human psychophysiology activity monitoring. That system including a EMFIT, microwave, fiber optic and capacitive sensors.

  9. Acoustic (loudspeaker) facial EMG monitoring: II. Use of evoked EMG activity during acoustic neuroma resection.

    PubMed

    Prass, R L; Kinney, S E; Hardy, R W; Hahn, J F; Lüders, H

    1987-12-01

    Facial electromyographic (EMG) activity was continuously monitored via loudspeaker during eleven translabyrinthine and nine suboccipital consecutive unselected acoustic neuroma resections. Ipsilateral facial EMG activity was synchronously recorded on the audio channels of operative videotapes, which were retrospectively reviewed in order to allow detailed evaluation of the potential benefit of various acoustic EMG patterns in the performance of specific aspects of acoustic neuroma resection. The use of evoked facial EMG activity was classified and described. Direct local mechanical (surgical) stimulation and direct electrical stimulation were of benefit in the localization and/or delineation of the facial nerve contour. Burst and train acoustic patterns of EMG activity appeared to indicate surgical trauma to the facial nerve that would not have been appreciated otherwise. Early results of postoperative facial function of monitored patients are presented, and the possible value of burst and train acoustic EMG activity patterns in the intraoperative assessment of facial nerve function is discussed. Acoustic facial EMG monitoring appears to provide a potentially powerful surgical tool for delineation of the facial nerve contour, the ongoing use of which may lead to continued improvement in facial nerve function preservation through modification of dissection strategy.

  10. Passive acoustic monitoring of biological activity on coral reefs and in nearby waters

    NASA Astrophysics Data System (ADS)

    Lammers, Marc O.; Mooney, T. Aran; Brainard, Russell E.; Au, Whitlow W. L.

    2005-09-01

    Monitoring the changing state of coral reef habitats is a challenging task that is exacerbated when the reefs in question are in remote locations. Physical sensors provide a wide range of measurements of local environmental variables, but do not give an indication of biological activity. The preliminary findings of an effort to use the ambient sound field as a means of characterizing and monitoring biological activity on coral reefs and surrounding waters are reported. Moored recording systems were developed to sample the sound field of reefs on Oahu, Hawaii for 1-min periods, at 30-min intervals, for 10 days at a time. Snapping shrimp produce the dominant acoustic energy on the reefs examined and exhibit clear diel acoustic trends. Peaks in activity consistently occur during crepuscular periods. At frequencies below 2 kHz, many fish sounds occur, which also exhibit distinct temporal variability. Cetacean sounds are also common, indicating the occurrence of an apex predator in the area. Many sounds can be detected automatically, making the examination of the sound field an efficient means of tracking acoustically active species. The results indicate that acoustic monitoring may be an effective means of tracking biological activity at locations where traditional surveys are impractical.

  11. The application of inertial and magnetic sensors to the monitoring of calf muscle pump activity.

    PubMed

    O'Donovan, Karol J; Bourke, Alan K; O'Keeffe, Derek T; Olaighin, Gearóid

    2009-01-01

    On long distance journeys passengers at high risk from deep vein thrombosis (DVT) are recommended to exercise on a regular basis to contract the calf muscle pump and encourage venous return. If a passenger fails to complete an exercise program that induces active contraction of the calf muscle pump they will remain at increased risk of DVT. This paper presents a novel inertial and magnetic sensor-based technique for monitoring calf muscle pump activity. The technique could be implemented into a system for monitoring the level of calf muscle pump activity in persons with limited mobility. Such a system could be used to provide a reminder to the user that there is a need to exercise should they have forgotten to exercise, failed to exercise sufficiently or exercised incorrectly. The proposed technique was evaluated by comparison with calf muscle pump activity measured using an electromyography (EMG) sensor. Results show that the technique can be used to monitor calf muscle pump activity over a wide range of leg exercises.

  12. Physical activity monitoring in obese people in the real life environment

    PubMed Central

    2009-01-01

    Background Obesity is a major problem especially in western countries and several studies underline the importance of physical activity to enhance diet. Currently there is increasing interest in instruments for monitoring daily physical activity. The purpose of this pilot study was to appraise the qualitative and quantitative differences in physical activities and gait analysis parameters in control and obese subjects by means of an innovative tool for the monitoring of physical activity. Methods Twenty-six obese patients, 16 women and 10 men, aged 22 to 69 years with Body Mass Index (BMI) between 30 and 51.4 kg/m2, were compared with 15 control subjects, 4 men and 11 women, aged 24 to 69 with BMI between 18 and 25 kg/m2 during daily physical activities. The IDEEA device (Minisun, Fresno, CA), based on a wearable system of biaxial accelerometers and able to continuously record the physical activities and energy expenditure of a subject in time was used. Time spent in different physical activities such as standing, sitting, walking, lying, reclining, stepping, energy expenditure and gait parameters (velocity, stance duration, etc) were measured during a 24-hours period. Results A trend toward a reduced number of steps was present, associated to reduced speed, reduced cadence and reduced rate of single and double limb support (SLS/DLS). Moreover, obese people spent significant less time stepping, less time lying and more time in a sitting or reclined position during the night. The energy expenditure during a 24-hours period was higher in the obese compared to controls. Conclusions The study provided objective parameters to differentiate the daily motor activity of obese subjects with respect to controls, even a larger population is required to confirm these findings. The device used can be of support in programming educational activities for life style modification in obese people as well as for monitoring the results of various kinds of intervention in these

  13. Recent Advances in Free-Living Physical Activity Monitoring: A Review

    PubMed Central

    Andre, David; Wolf, Donna L.

    2007-01-01

    It has become clear recently that the epidemic of type 2 diabetes sweeping the globe is associated with decreased levels of physical activity and an increase in obesity. Incorporating appropriate and sufficient physical activity into one's life is an essential component of achieving and maintaining a healthy weight and overall health, especially for those with type II diabetes mellitus. Regular physical activity can have a positive impact by lowering blood glucose, helping the body to be more efficient at using insulin. There are other substantial benefits for patients with diabetes, including prevention of cardiovascular disease, hyperlipidemia, hypertension, and obesity. Several complications of utilizing a self-care treatment methodology involving exercise include (1) patients may not know how much activity that they engage in and (2) health-care providers do not have objective measurements of how much activity their patients perform. However, several technological advances have brought a variety of activity monitoring devices to the market that can address these concerns. Ranging from simple pedometers to multisensor devices, the different technologies offer varying levels of accuracy, comfort, and reliability. The key notion is that by providing feedback to the patient, motivation can be increased and targets can be set and aimed toward. Although these devices are not specific to the treatment of diabetes, the importance of physical activity in treating the disease makes an understanding of these devices important. This article reviews these physical activity monitors and describes the advantages and disadvantages of each. PMID:19885145

  14. In situ Raman and X-ray spectroscopies to monitor microbial activities under high hydrostatic pressure.

    PubMed

    Oger, Phil M; Daniel, Isabelle; Picard, Aude

    2010-02-01

    Until recently, monitoring of cells and cellular activities at high hydrostatic pressure (HHP) was mainly limited to ex situ observations. Samples were analyzed prior to and following the depressurization step to evaluate the effect of the pressure treatment. Such ex situ measurements have several drawbacks: (i) it does not allow for kinetic measurements and (ii) the depressurization step often leads to artifactual measurements. Here, we describe recent advances in diamond anvil cell (DAC) technology to adapt it to the monitoring of microbial processes in situ. The modified DAC is asymmetrical, with a single anvil and a diamond window to improve imaging quality and signal collection. Using this novel DAC combined to Raman and X-ray spectroscopy, we monitored the metabolism of glucose by baker's yeast and the reduction of selenite by Agrobacterium tumefaciens in situ under HHP. In situ spectroscopy is also a promising tool to study piezophilic microorganisms.

  15. An Evidence-Based Adoption of Technology Model for Remote Monitoring of Elders’ Daily Activities

    PubMed Central

    2011-01-01

    What benefit will new technologies offer if they are inadequately or not used? This work presents a meta-synthesis of adoption of technology related findings from four innovative monitoring intervention research studies with older adults and their informal and/or formal caregivers. Each study employed mixed methods analyses that lead to an understanding of the key variables that influenced adoption of telephone and Internet based wireless remote monitoring technologies by elders and their caregivers. The studies were all conducted in “real world” homes ranging from solo residences to multi-story independent living residential buildings. Insights gained came from issues not found in controlled laboratory environments but in the complex interplay of family-elder-staff dynamics around balancing safety and independence. Findings resulted in an adoption of technology model for remote monitoring of elders’ daily activities derived from evidence based research to advance both practical and theoretical development in the field of gerontechnology. PMID:21423843

  16. Multisensor fusion for atrial and ventricular activity detection in coronary care monitoring

    PubMed Central

    Hernández, Alfredo I.; Carrault, Guy; Mora, Fernando; Thoraval, Laurent; Passariello, Gianfranco; Schleich, Jean-Marc

    1999-01-01

    Information management for critical care monitoring is still a very difficult task. Medical staff is often overwhelmed by the amount of data provided by the increased number of specific monitoring devices and instrumentation, and the lack of an effective automated system. Specifically, a basic task such as arrhythmia detection still produce an important amount of undesirable alarms, due in part to the mechanistic approach of current monitoring systems. In this work, multi-sensor and multi-source data fusion schemes to improve atrial and ventricular activity detection in critical care environments are presented. Applications of these schemes are quantitatively evaluated and compared with current methods, showing the potential advantages of data fusion techniques for event detection in noise corrupted signals. PMID:10513122

  17. Assessment and Design of Water Quality Monitoring Networks with respect to Shale Gas Activities in Pennsylvania

    NASA Astrophysics Data System (ADS)

    Arjmand, S.; Abad, J. D.; Brantley, S. L.

    2013-12-01

    Over the past few years, hydraulic fracturing and horizontal drilling techniques have been extensively used to extract shale gas from the Marcellus Shale. Likewise, several environmental violations that have been repeatedly reported in drilling sites have created greater awareness on potentially adverse environmental impacts of shale gas. Long-term monitoring in the Marcellus Shale is the key to maintain and improve the quality of water supplies in future. Currently, the absence of an efficient water quality monitoring network prevents the detection and source identification of contaminants associated with shale gas activities. Evaluation and re-design of monitoring networks from time to time is a major step towards efficient water resources planning and management. In this study, we assessed the performance of the current water quality monitoring network with respect to the shale gas development in Pennsylvania. For better evaluation, the Oil and Gas Compliance Report by the Pennsylvania Department of Environmental Protection between January 2005 and May 2013 was compiled. Using statistical and GIS methods each violation item was examined against the number and location of sensors in the current monitoring network. The results helped identify the adequacy of the number of sensors to detect the potential contamination. Moreover, to improve the performance and to lower the long-term monitoring costs, we re-designed the network using optimization methods. This optimal system maximizes the understanding of the aquifer condition and investigates the shale gas industry impacts on shallow aquifers, and it is applicable to other watersheds with shale oil and gas drilling activities.

  18. AVHRR-based drought-observing system for monitoring the environment and socioeconomic activities

    NASA Astrophysics Data System (ADS)

    Kogan, F.

    From all natural disaster, drought is the least understandable and the most damaging environmental phenomenon. Although in pre-satellite era, climate data were used for drought monitoring, drought specifics created problems in early drought detection start/end, monitoring its expansion/contraction, intensity and area coverage and the most important, timely estimation of the impacts on the environment and socioeconomic activities. The latest prevented to take prompt measures in mitigating negative consequences of drought for the society. Advances in remote sensing of the past ten years, contributed to the development of comprehensive drought monitoring system and numerous applications, which helped to make decisions for monitoring the environment and predicting sustainable socioeconomic activities. This paper discusses satellite-based land-surface observing system, which provides wells of information used for monitoring such unusual natural disaster as drought. This system was developed from the observations of the Advanced Very High Resolution Radiometer (AVHRR) flown on NOAA operational polar-orbiting satellites. The AVHRR data were packed into the Global Vegetation Index (GVI) product, which have served the global community since 1981. The GVI provided reflectances and indices (4 km spacial resolution) every seven days for each 16 km map cell between 75EN and 55ES covering all land ecosystems. The data includes raw and calibrated radiances in the visible, near infrared and infrared spectral bands, processed (with eliminated high frequency noise) radiances, normalized difference vegetation index (NDVI), 20-year climatology, vegetation condition indices and also products, such as vegetation health, drought, vegetation fraction, fire risk etc. In the past ten years, users around the world used this information addressing different issues of drought impacts on socioeconomic activities and responded positively to real time drought information place regularly on the

  19. Automated swimming activity monitor for examining temporal patterns of toxicant effects on individual Daphnia magna.

    PubMed

    Bahrndorff, Simon; Michaelsen, Thomas Yssing; Jensen, Anne; Marcussen, Laurits Faarup; Nielsen, Majken Elley; Roslev, Peter

    2016-07-01

    Aquatic pollutants are often biologically active at low concentrations and impact on biota in combination with other abiotic stressors. Traditional toxicity tests may not detect these effects, and there is a need for sensitive high-throughput methods for detecting sublethal effects. We have evaluated an automated infra-red (IR) light-based monitor for recording the swimming activity of Daphnia magna to establish temporal patterns of toxicant effects on an individual level. Activity was recorded for 48 h and the sensitivity of the monitor was evaluated by exposing D. magna to the reference chemicals K2 Cr2 O7 at 15, 20 and 25 °C and 2,4-dichlorophenol at 20 °C. Significant effects (P < 0.001) of toxicant concentrations, exposure time and incubation temperatures were observed. At 15 °C, the swimming activity remained unchanged for 48 h at sublethal concentrations of K2 Cr2 O7 whereas activity at 20 and 25 °C was more biphasic with decreases in activity occurring after 12-18 h. A similar biphasic pattern was observed after 2,4-dichlorophenol exposure at 20 °C. EC50 values for 2,4-dichlorophenol and K2 Cr2 O7 determined from automated recording of swimming activity showed increasing toxicity with time corresponding to decreases in EC50 of 0.03-0.07 mg l(-1) h(-1) . EC50 values determined after 48 h were comparable or lower than EC50 values based on visual inspection according to ISO 6341. The results demonstrated that the swimming activity monitor is capable of detecting sublethal behavioural effects that are toxicant and temperature dependent. The method allows EC values to be established at different time points and can serve as a high-throughput screening tool in toxicity testing. Copyright © 2015 John Wiley & Sons, Ltd.

  20. Recent Developments in Active and Passive Distributed Temperature Sensing for Soil Moisture Monitoring

    NASA Astrophysics Data System (ADS)

    Steele-Dunne, S. C.; Dong, J.; Hoes, O.; Van De Giesen, N.; Sayde, C.; Ochsner, T. E.; Selker, J. S.

    2015-12-01

    In this presentation we will review recent developments in both active and passive Distributed Temperature Sensing (DTS) for soil moisture monitoring. DTS involves using fiber-optic cables to measure temperature at sub-meter resolution along cables up to several kilometers in length. Soil thermal properties depend on soil moisture. Hence, temperature variations either in response to externally-applied heating (active) or the response to net radiation (passive) can be monitored and used to infer soil moisture. DTS occupies a unique measurement niche, potentially providing soil moisture information at sub-meter resolution over extents on the order of km at sub-daily time steps. It complements observations from point sensors to other innovative measurement techniques like cosmic ray neutron detection methods and GPS reflectometry. DTS is being developed as a tool for the validation of soil moisture observations from remote sensing and for hydrological field investigations. Here, we will discuss both technological and theoretical advances in active and passive DTS for soil moisture monitoring. We will present data from new installations in the Netherlands and the USA to illustrate recent developments. In particular, we will focus on the value of combining temperature observations from DTS with physical models using data assimilation. In addition to yielding improved soil moisture and temperature profile estimates, recent research has shown the potential to also derive information on the soil thermal and hydraulic properties. We will conclude by outlining the current challenges, with particular emphasis on combining active and passive DTS.