Science.gov

Sample records for activation takes place

  1. 12 CFR 536.50 - Where insurance activities may take place.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Where insurance activities may take place. 536.50 Section 536.50 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY CONSUMER PROTECTION IN SALES OF INSURANCE § 536.50 Where insurance activities may take place. (a) General rule....

  2. 12 CFR 208.85 - Where insurance activities may take place.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 2 2011-01-01 2011-01-01 false Where insurance activities may take place. 208.85 Section 208.85 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE... Protection in Sales of Insurance § 208.85 Where insurance activities may take place. (a) General rule. A...

  3. 12 CFR 343.50 - Where insurance activities may take place.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Where insurance activities may take place. 343.50 Section 343.50 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY CONSUMER PROTECTION IN SALES OF INSURANCE § 343.50 Where insurance activities may take place. (a) General rule. A bank must, to...

  4. 12 CFR 14.50 - Where insurance activities may take place.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Where insurance activities may take place. 14.50 Section 14.50 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY CONSUMER PROTECTION IN SALES OF INSURANCE § 14.50 Where insurance activities may take place. (a) General rule. A...

  5. Studying Activities That Take Place in Speech Interactions: A Theoretical and Methodological Framework

    ERIC Educational Resources Information Center

    Saint-Dizier de Almeida, Valérie; Colletta, Jean-Marc; Auriac-Slusarczyk, Emmanuelle; Specogna, Antonietta; Simon, Jean-Pascal; Fiema, Gabriela; Luxembourger, Christophe

    2016-01-01

    The paper proposes a theoretical and methodological framework based on a pluralistic, concerted approach to the study of activities that take place in and through speech interactions. The framework has a general scope, applying to any collective activity taking form through language interactions. It contributes to a fuller understanding of the…

  6. 12 CFR 343.50 - Where insurance activities may take place.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... OF GENERAL POLICY CONSUMER PROTECTION IN SALES OF INSURANCE § 343.50 Where insurance activities may... consumer who seeks to purchase an insurance product or annuity to a qualified person who sells that product only if the person making the referral receives no more than a one-time, nominal fee of a fixed...

  7. Place-focused physical activity research, human agency, and social justice in public health: taking agency seriously in studies of the built environment.

    PubMed

    Blacksher, Erika; Lovasi, Gina S

    2012-03-01

    Built environment characteristics have been linked to health outcomes and health disparities. However, the effects of an environment on behavior may depend on human perception, interpretation, motivation, and other forms of human agency. We draw on epidemiological and ethical concepts to articulate a critique of research on the built environment and physical activity. We identify problematic assumptions and enumerate both scientific and ethical reasons to incorporate subjective perspectives and public engagement strategies into built environment research and interventions. We maintain that taking agency seriously is essential to the pursuit of health equity and the broader demands of social justice in public health, an important consideration as studies of the built environment and physical activity increasingly focus on socially disadvantaged communities. Attention to how people understand their environment and navigate competing demands can improve the scientific value of ongoing efforts to promote active living and health, while also better fulfilling our ethical obligations to the individuals and communities whose health we strive to protect. PMID:21940195

  8. Mechanism of action of electrochemically active carbons on the processes that take place at the negative plates of lead-acid batteries

    NASA Astrophysics Data System (ADS)

    Pavlov, D.; Rogachev, T.; Nikolov, P.; Petkova, G.

    It is known that negative plates of lead-acid batteries have low charge acceptance when cycled at high rates and progressively accumulate lead sulphate on high-rate partial-state-of-charge (HRPSoC) operation in hybrid-electric vehicle (HEV) applications. Addition of some carbon or graphite forms to the negative paste mix improves the charge efficiency and slows down sulfation of the negative plates. The present investigation aims to elucidate the contribution of electrochemically active carbon (EAC) additives to the mechanism of the electrochemical reactions of charge of the negative plates. Test cells are assembled with four types of EAC added to the negative paste mix in five different concentrations. Through analysis of the structure of NAM (including specific surface and pore radius measurements) and of the electrochemical parameters of the test cells on HRPSoC cycling, it is established that the electrochemical reaction of charge Pb 2+ + 2e - → Pb proceeds at 300-400 mV lower over-potentials on negative plates doped with EAC additives as compared to the charge potentials of cells with no carbon additives. Hence, electrochemically active carbons have a highly catalytic effect on the charge reaction and are directly involved in it. Consequently, the reversibility of the charge/discharge processes is improved, which eventually leads to longer battery cycle life. Thus, charging of the negative plates proceeds via a parallel mechanism on the surfaces of both Pb and EAC particles, at a higher rate on the EAC phase. Cells with EAC in NAM have the longest cycle life when their NAM specific surface is up to 4 m 2 g -1 against 0.5 m 2 g -1 for the lead surface. The proposed parallel mechanism of charge is verified experimentally on model Pb/EAC/PbSO 4 and Pb/EAC electrodes. During the charge and discharge cycles of the HRPSoC test, the EAC particles are involved in dynamic adsorption/desorption on the lead sulfate and lead surfaces. Another effect of electrochemically

  9. Short communication: Little change takes place in Camembert-type cheese water activities throughout ripening in terms of relative humidity and salt.

    PubMed

    Leclercq-Perlat, M-N; Hélias, A; Corrieu, G

    2013-01-01

    Water activity (a(w)) affects the growth and activity of ripening microorganisms. Moreover, it is generally accepted that a(w) depends on relative humidity (RH) and salt content; these 3 variables were usually measured on a given day in a cheese without the microorganism layer and without accounting for a distinction between the rind, the underrind, and the core. However, a(w) dynamics have never been thoroughly studied throughout cheese ripening. Experimental Camembert cheeses were ripened under controlled and aseptic conditions (temperature, gaseous atmosphere, and RH) for 14 d. In this study, only RH was varied. Samples were taken from the cheese (microorganism layer)-air interface, the rind, and the core. The aw of the cheese-air interface did not change over ripening when RH varied between 91 and 92% or between 97 and 98%. However, on d 5, we observed a small but significant increase in a(w), which coincided with the beginning of growth of Penicillium camemberti mycelia. After d 3, no significant differences were found between the a(w) of the cheese-air interface, the rind, and the core. From d 0 to 3, cheese rind a(w) increased from 0.94 to 0.97, which was probably due to the diffusion of salt from the rind to the core: NaCl content in the rind decreased from 3.7 to 1.6% and NaCl content in the core increased from 0.0 to 1.6%. Nevertheless, aw did not significantly vary in the core, raising questions about the real effect of salt on a(w). PMID:24404582

  10. Does olfactory specific satiety take place in a natural setting?

    PubMed

    Fernandez, P; Bensafi, M; Rouby, C; Giboreau, A

    2013-01-01

    Olfactory-specific satiety (OSS) is characterized by a specific decrease in the odor pleasantness of a food eaten to satiety or smelled without ingestion. The usual protocol for studying OSS takes place in laboratory, a setting rather removed from the real world. Here, we set out to examine OSS in a natural setting: during a meal in a restaurant. We hypothesized that an aroma contained in a food that is eaten at the beginning of a meal decreases the pleasantness of the flavor of a food with the same aroma eaten at the end of the meal. In the first experiment (Experiment 1), a test group received an appetizer flavored with a test aroma (anise) at the beginning of the meal. After the main dish, they received a dessert flavored with the same aroma. A control group received the same aromatized dessert, but after a non-aromatized appetizer. This experiment was replicated (Experiment 2) using verbena as the test aroma. For both experiments, results revealed that aroma pleasantness, but not intensity or familiarity, significantly decreased in the test groups vs. the control groups. These findings extend the concept of OSS to a realistic eating context. PMID:23079143

  11. 49 CFR 40.221 - Where does an alcohol test take place?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Where does an alcohol test take place? 40.221... WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Testing Sites, Forms, Equipment and Supplies Used in Alcohol Testing § 40.221 Where does an alcohol test take place? (a) A DOT alcohol test must take place at...

  12. 49 CFR 40.221 - Where does an alcohol test take place?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 1 2012-10-01 2012-10-01 false Where does an alcohol test take place? 40.221... WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Testing Sites, Forms, Equipment and Supplies Used in Alcohol Testing § 40.221 Where does an alcohol test take place? (a) A DOT alcohol test must take place at...

  13. 49 CFR 40.221 - Where does an alcohol test take place?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Where does an alcohol test take place? 40.221... WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Testing Sites, Forms, Equipment and Supplies Used in Alcohol Testing § 40.221 Where does an alcohol test take place? (a) A DOT alcohol test must take place at...

  14. 49 CFR 40.221 - Where does an alcohol test take place?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Where does an alcohol test take place? 40.221... WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Testing Sites, Forms, Equipment and Supplies Used in Alcohol Testing § 40.221 Where does an alcohol test take place? (a) A DOT alcohol test must take place at...

  15. Kiwifruit: taking its place in the global fruit bowl.

    PubMed

    Ward, Carol; Courtney, David

    2013-01-01

    While the world total production of kiwifruit has increased by over 50% during the last decade, the kiwifruit remains a niche fruit, taking up an estimated 0.22% of the global fruit bowl, which is dominated by apples, oranges, and bananas. Even though kiwifruit's share of the global fruit bowl has remained largely unchanged over the past 15 years, the scope for growth in the category is significant, with the nutritional and production characteristics of kiwifruit being on the right side of key global consumer trends around health and sustainability. Taking advantage of these consumer trends is one of two key challenges for the global kiwifruit industry. The second challenge is to harness the diverse natural and cultivated range of kiwifruit varieties (colors, flavors, sizes, and shapes) to stimulate the interest of consumers and grow the share of kiwifruit in the fruit basket through selecting cultivars that can develop meaningful market segments and meet consumer demand. PMID:23394979

  16. 14 CFR 11.53 - What takes place at a public meeting?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false What takes place at a public meeting? 11.53 Section 11.53 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURAL RULES GENERAL RULEMAKING PROCEDURES Rulemaking Procedures Public Meetings and Other Proceedings § 11.53 What takes place at a public...

  17. 2012 CCCC Chair's Address: Stories Take Place--A Performance in One Act

    ERIC Educational Resources Information Center

    Powell, Malea

    2012-01-01

    This is a written version of the address that Malea Powell gave at the Conference on College Composition and Communication (CCCC) Convention in St. Louis, Missouri, on Thursday, March 22, 2012. This address is a collection of stories. According to her, stories take place. Stories practice place into space. Stories produce habitable spaces. She…

  18. [Marketing approval and market surveillance of medical devices in Germany: Where does policy integration take place?].

    PubMed

    Lang, Achim

    2014-01-01

    Since 2011 new regulatory measures regarding medical devices have been set up with the aim to eliminate obstacles to innovations and to find more coordinated ways to marketing authorisation and market surveillance. This essay investigates whether these new and existing coordination mechanisms build up to a Joined-up Government approach. The analysis shows that the regulatory process should be adjusted along several dimensions. First, many organisations lack awareness regarding their stakeholders and focus solely on their immediate organisational activities. Second, the regulatory process (marketing authorisation and market surveillance) is too fragmented for an effective communication to take place. Finally, the underlying strategy process is an ad-hoc approach lacking continuity and continued involvement of, in particular, the responsible federal ministries. PMID:25066351

  19. Makro- and micromorphological evidence of processes taking place during Albeluvisol development in S Norway

    NASA Astrophysics Data System (ADS)

    Sauer, Daniela; Schülli-Maurer, Isabelle; Sperstad, Ragnhild; Sørensen, Rolf

    2014-05-01

    We studied two soil chronosequences in S Norway to identify processes involved in Albeluvisol formation. For this purpose, field observation of vertical and horizontal sections of soil profiles, soil chemical and mineralogical analyses were carried out, and in particular, micromorphological analysis was applied. The study area is located at the western and eastern side of the Oslofjord, S Norway, in the counties Vestfold and Østfold. This region is characterized by continuous glacio-isostatic uplift over the entire Holocene. Hence, the age of the land surface continuously increases from the coast towards higher elevations. Twelve soil profiles in loamy marine sediments were studied. Based on macro- and micromorphological observations and analytical data progressive soil formation is characterized as follows: As soon as the land surface is raised above sea level, five major processes are initiated: 1) development of deep desiccation cracks, forming a polygonal pattern; 2) compaction, taking place as soon as the coarse pores have been drained; 3) pyrite oxidation and release of sulfuric acid; 4) carbonate dissolution by acids from pyrite and iron oxidation resulting in rapid decarbonatization of the originally calcareous sediments; 5) precipitation of iron hypocoatings and coatings in the capillary fringe Soon after these very early processes have taken place, limited water permeability of the fine-textured sediments leads to horizon differentiation into Ah, Eg and Btg horizons within less than 2.1 ka. Eg horizons become lighter in colour with time. Also illuvial clay is already observed in the 2.1 ka-old soil. Soil pH in the upper part of the E horizon of this soil is already too low for significant clay mobilization. Clay illuviation is still active in all soils studied, but the upper boundary of the zone where pH favours clay mobilization is at 20-50 cm depth. Progressive clay illuviation over time is recorded in increasing thickness of clay coatings and

  20. Active place recognition using image signatures

    NASA Astrophysics Data System (ADS)

    Engelson, Sean P.

    1992-11-01

    For reliable navigation, a mobile robot needs to be able to recognize where it is in the world. We previously described an efficient and effective image-based representation of perceptual information for place recognition. Each place is associated with a set of stored image signatures, each a matrix of numbers derived by evaluating some measurement functions over large blocks of pixels. One difficulty, though, is the large number of inherently ambiguous signatures which bloats the database and makes recognition more difficult. Furthermore, since small differences in orientation can produce very different images, reliable recognition requires many images. These problems can be ameliorated by using active methods to select the best signatures to use for the recognition. Two criteria for good images are distinctiveness (is the scene distinguishable from others?) and stability (how much do small viewpoint motions change image recognizability?). We formulate several heuristic distinctiveness metrics which are good predictors of real image distinctiveness. These functions are then used to direct the motion of the camera to find locally distinctive views for use in recognition. This method also produces some modicum of stability, since it uses a form of local optimization. We present the results of applying this method with a camera mounted on a pan-tilt platform.

  1. Using PlacesOnline in Instructional Activities

    ERIC Educational Resources Information Center

    Longan, Michael W.; Owusu, Francis; Roseman, Curtis C.

    2008-01-01

    PlacesOnLine.org is a Web portal that provides easy access to high quality Web sites that focus on places from around the world. It is intended for use by a wide range of people, including professional geographers, teachers and students at all levels, and the general public. This article explores the potential uses of PlacesOnLine as an…

  2. Questions and Answers Regarding Actions to Take When Ending Shelter-in-Place

    SciTech Connect

    Shumpert, B.

    2003-12-30

    Shelter-in-place has found increasing acceptance as an effective protective action option for communities participating in the Chemical Stockpile Emergency Preparedness Program. Studies have confirmed that it can provide optimum protection under certain accident conditions. However, emergency managers and planners, as well as the public, continue to be troubled by the need to end sheltering when the plume has passed in order to avoid sustained exposure to the small amount of agent that has penetrated the shelter. One of the concerns posed by this necessity is uncertainty regarding what hazards will then be faced in the environment outside the shelter and what actions can be taken to avoid those hazards. This report attempts to address those uncertainties. It recognizes that there is an extremely low probability that the environment outside the shelter will be contaminated with chemical agent residue. However, as people comply with an official recommendation to leave their shelters, they probably can't be certain that the environment is free from contamination. Therefore, this report identifies and explains specific and simple actions they can take to avoid the possibility of exposure to chemical agent hazards outside their shelters. It addresses such issues as the actions people should take upon ending shelter-in-place, what clothing they should wear, how they should handle animals, and what they should do about food in their homes and produce in their gardens.

  3. Endolymphatic calcium supply for fish otolith growth takes place via the proximal portion of the otocyst.

    PubMed

    Ibsch, M; Anken, R; Beier, M; Rahmann, H

    2004-09-01

    The presence of calcium within the utricle of larval cichlid fish Oreochromis mossambicus was analysed by means of energy-filtering transmission electron microscopy. Electron-spectroscopic imaging and electron energy loss spectra revealed discrete calcium precipitations that were more numerous in the proximal endolymph than in the distal endolymph, clearly indicating a decreasing proximo-distal gradient. This decreasing proximo-distal gradient was also present within the proximal endolymph between the sensory epithelium and the otolith. Further calcium particles covered the peripheral proteinaceous layer of the otolith. They were especially pronounced at the proximal surface of the otolith indicating that otolithic calcium incorporation takes place here. Other calcium precipitates accumulated at the macular junctions clearly supporting an earlier assumption according to which the endolymph is supplied with calcium via a paracellular pathway. The present results clearly show that the apical region of the macular epithelium is involved in the release of calcium and that the calcium supply of the otoliths takes place via the proximal endolymph. PMID:15300493

  4. 49 CFR 40.41 - Where does a urine collection for a DOT drug test take place?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Where does a urine collection for a DOT drug test... in DOT Urine Collections § 40.41 Where does a urine collection for a DOT drug test take place? (a) A urine collection for a DOT drug test must take place in a collection site meeting the requirements...

  5. The 'taking place' of health and wellbeing: towards non-representational theory.

    PubMed

    Andrews, Gavin J; Chen, Sandra; Myers, Samantha

    2014-05-01

    For the last two decades health geography has focused on the dynamics between health and place. Although the social constructivist perspective of much research has provided many insights into the meanings of health and health care arguably, mirroring progress in the parent discipline of human geography, there could be a far more serious engagement with non-representational theory and the 'taking place' of health and health care. To showcase the importance and potential of this broadly, the idea of wellbeing is re-approached. The paper reflects on the ways wellbeing has been treated in research primarily as a meaningful and relatively prescribed state of life, to the neglect of process. Based on this critique, a qualitative study then illustrates the most immediate and everyday ways wellbeing might arise through 'affect'; the pre-personal mobile energies and intensities that result from physical encounters within assemblages of bodies and objects. Indeed, theoretically the findings support the proposition that, at one level, wellbeing might not be taken from environment but instead might emerge as the affective environment. They certainly raise awareness of how much in health might originate at the surface, prior to meaning, within life's infinite spatial doings, and thus they launch some final thoughts on the wider challenges and opportunities for non-representational health geographies. PMID:24675389

  6. Modeling place field activity with hierarchical slow feature analysis

    PubMed Central

    Schönfeld, Fabian; Wiskott, Laurenz

    2015-01-01

    What are the computational laws of hippocampal activity? In this paper we argue for the slowness principle as a fundamental processing paradigm behind hippocampal place cell firing. We present six different studies from the experimental literature, performed with real-life rats, that we replicated in computer simulations. Each of the chosen studies allows rodents to develop stable place fields and then examines a distinct property of the established spatial encoding: adaptation to cue relocation and removal; directional dependent firing in the linear track and open field; and morphing and scaling the environment itself. Simulations are based on a hierarchical Slow Feature Analysis (SFA) network topped by a principal component analysis (ICA) output layer. The slowness principle is shown to account for the main findings of the presented experimental studies. The SFA network generates its responses using raw visual input only, which adds to its biological plausibility but requires experiments performed in light conditions. Future iterations of the model will thus have to incorporate additional information, such as path integration and grid cell activity, in order to be able to also replicate studies that take place during darkness. PMID:26052279

  7. What it Takes to Successfully Implement Technology for Aging in Place: Focus Groups With Stakeholders

    PubMed Central

    Wouters, Eveline JM; Luijkx, Katrien G; Vrijhoef, Hubertus JM

    2016-01-01

    Background There is a growing interest in empowering older adults to age in place by deploying various types of technology (ie, eHealth, ambient assisted living technology, smart home technology, and gerontechnology). However, initiatives aimed at implementing these technologies are complicated by the fact that multiple stakeholder groups are involved. Goals and motives of stakeholders may not always be transparent or aligned, yet research on convergent and divergent positions of stakeholders is scarce. Objective To provide insight into the positions of stakeholder groups involved in the implementation of technology for aging in place by answering the following questions: What kind of technology do stakeholders see as relevant? What do stakeholders aim to achieve by implementing technology? What is needed to achieve successful implementations? Methods Mono-disciplinary focus groups were conducted with participants (n=29) representing five groups of stakeholders: older adults (6/29, 21%), care professionals (7/29, 24%), managers within home care or social work organizations (5/29, 17%), technology designers and suppliers (6/29, 21%), and policy makers (5/29, 17%). Transcripts were analyzed using thematic analysis. Results Stakeholders considered 26 different types of technologies to be relevant for enabling independent living. Only 6 out of 26 (23%) types of technology were mentioned by all stakeholder groups. Care professionals mentioned fewer different types of technology than other groups. All stakeholder groups felt that the implementation of technology for aging in place can be considered a success when (1) older adults’ needs and wishes are prioritized during development and deployment of the technology, (2) the technology is accepted by older adults, (3) the technology provides benefits to older adults, and (4) favorable prerequisites for the use of technology by older adults exist. While stakeholders seemed to have identical aims, several underlying

  8. OECD Global Science Forum's Astronomy Workshop to take place in Munich

    NASA Astrophysics Data System (ADS)

    2003-11-01

    members of the national astronomical community. The International Astronomical Union (IAU) and the European Southern Observatory (ESO) are explicitly represented. Experts from the world-wide astronomy community have been invited to set the stage and provide input for the discussions. The choice by Germany and the OECD to make Munich the venue of this Global Science Forum Workshop is no coincidence. It is a recognition of the important role played by many institutions in the Munich region in the field of Astronomy and Astrophysics. They include the Ludwig-Maximilians-Universität where the Workshop will take place, the Max-Planck-Institut für Astrophysik, the Max-Planck Institut für Extraterrestrische Physik and the European Southern Observatory. These institutions are all participating in large programmes and projects in astronomy. ESO, for its part, is at the leading edge of world astronomy with its flagship facility, the Very Large Telescope in Paranal (Chile) and the newly started ALMA project at Chajnantor (Chile), being carried out in partnership between Europe and North America. Public Talks (Munich) on December 1, 2003 As a prelude to the Workshop, two public keynote presentations will take place on December 1 at the Deutsches Museum in Munich at 18:00 CET. The speakers are Malcolm Longair, Jacksonian Professor of Natural Philosophy and Head of Laboratory, Cavendish Laboratory, Cambridge (UK) and Martin Harwit, Professor Emeritus of Astronomy, Cornell University, and former Director of the National Air and Space Museum, Washington, DC (USA). The talks will be given in English and the entry to this public event is free. Professor Longair will speak on "Astrophysics and Cosmology in the Twenty-First Century" and Professor Harwit will speak on "The Growth of Understanding of our Universe". You can find more informaton on the Public Talks web page.

  9. Activity-dependent plasticity of hippocampal place maps.

    PubMed

    Schoenenberger, Philipp; O'Neill, Joseph; Csicsvari, Jozsef

    2016-01-01

    Hippocampal neurons encode a cognitive map of space. These maps are thought to be updated during learning and in response to changes in the environment through activity-dependent synaptic plasticity. Here we examine how changes in activity influence spatial coding in rats using halorhodopsin-mediated, spatially selective optogenetic silencing. Halorhoposin stimulation leads to light-induced suppression in many place cells and interneurons; some place cells increase their firing through disinhibition, whereas some show no effect. We find that place fields of the unaffected subpopulation remain stable. On the other hand, place fields of suppressed place cells were unstable, showing remapping across sessions before and after optogenetic inhibition. Disinhibited place cells had stable maps but sustained an elevated firing rate. These findings suggest that place representation in the hippocampus is constantly governed by activity-dependent processes, and that disinhibition may provide a mechanism for rate remapping. PMID:27282121

  10. Activity-dependent plasticity of hippocampal place maps

    PubMed Central

    Schoenenberger, Philipp; O'Neill, Joseph; Csicsvari, Jozsef

    2016-01-01

    Hippocampal neurons encode a cognitive map of space. These maps are thought to be updated during learning and in response to changes in the environment through activity-dependent synaptic plasticity. Here we examine how changes in activity influence spatial coding in rats using halorhodopsin-mediated, spatially selective optogenetic silencing. Halorhoposin stimulation leads to light-induced suppression in many place cells and interneurons; some place cells increase their firing through disinhibition, whereas some show no effect. We find that place fields of the unaffected subpopulation remain stable. On the other hand, place fields of suppressed place cells were unstable, showing remapping across sessions before and after optogenetic inhibition. Disinhibited place cells had stable maps but sustained an elevated firing rate. These findings suggest that place representation in the hippocampus is constantly governed by activity-dependent processes, and that disinhibition may provide a mechanism for rate remapping. PMID:27282121

  11. 75 FR 27708 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-18

    ... take small numbers of marine mammals by harassment. Section 101(a)(5)(D) establishes a 45-day time... survey time is expected to take 30 days. The vessel that will be conducting this activity has not been.... The actual survey time is expected to take 45 days. Ice Gouge Survey As part of the feasibility...

  12. Coronavirus and Influenza Virus Proteolytic Priming Takes Place in Tetraspanin-Enriched Membrane Microdomains

    PubMed Central

    Earnest, James T.; Hantak, Michael P.; Park, Jung-Eun

    2015-01-01

    ABSTRACT Coronaviruses (CoVs) and low-pathogenicity influenza A viruses (LP IAVs) depend on target cell proteases to cleave their viral glycoproteins and prime them for virus-cell membrane fusion. Several proteases cluster into tetraspanin-enriched microdomains (TEMs), suggesting that TEMs are preferred virus entry portals. Here we found that several CoV receptors and virus-priming proteases were indeed present in TEMs. Isolated TEMs, when mixed with CoV and LP IAV pseudoparticles, cleaved viral fusion proteins to fusion-primed fragments and potentiated viral transductions. That entering viruses utilize TEMs as a protease source was further confirmed using tetraspanin antibodies and tetraspanin short hairpin RNAs (shRNAs). Tetraspanin antibodies inhibited CoV and LP IAV infections, but their virus-blocking activities were overcome by expressing excess TEM-associated proteases. Similarly, cells with reduced levels of the tetraspanin CD9 resisted CoV pseudoparticle transductions but were made susceptible by overproducing TEM-associated proteases. These findings indicated that antibodies and CD9 depletions interfere with viral proteolytic priming in ways that are overcome by surplus proteases. TEMs appear to be exploited by some CoVs and LP IAVs for appropriate coengagement with cell receptors and proteases. IMPORTANCE Enveloped viruses use their surface glycoproteins to catalyze membrane fusion, an essential cell entry step. Host cell components prime these viral surface glycoproteins to catalyze membrane fusion at specific times and places during virus cell entry. Among these priming components are proteases, which cleave viral surface glycoproteins, unleashing them to refold in ways that catalyze virus-cell membrane fusions. For some enveloped viruses, these proteases are known to reside on target cell surfaces. This research focuses on coronavirus and influenza A virus cell entry and identifies TEMs as sites of viral proteolysis, thereby defining subcellular

  13. 26 CFR 1.924(d)-1 - Requirement that economic processes take place outside the United States.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 10 2012-04-01 2012-04-01 false Requirement that economic processes take place outside the United States. 1.924(d)-1 Section 1.924(d)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Earned Income of Citizens of United States §...

  14. An Experimental Investigation of the Process of Isotope Exchange that Takes Place when Heavy Water Is Exposed to the Atmosphere

    ERIC Educational Resources Information Center

    Deeney, F. A.; O'Leary, J. P.

    2009-01-01

    We have used the recently developed method for rapid measurement of maximum density temperature to determine the rate at which hydrogen and deuterium isotope exchange takes place when a sample of heavy water is exposed to the atmosphere. We also provide a simple explanation for the observed linear rate of transition. (Contains 2 figures.)

  15. 76 FR 40697 - Water and Wastewater Trade Mission to Australia Taking Place September 12-15, 2011; Now Opened to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ... open and public manner, including publication in the Federal Register ( http://www.gpoaccess.gov/fr... International Trade Administration Water and Wastewater Trade Mission to Australia Taking Place September 12-15... federal and state levels, is working on strategies and projects aimed at securing future water...

  16. 78 FR 37209 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration RIN 0648-XC564 Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to Marine Seismic Survey in the Beaufort Sea,...

  17. 78 FR 64918 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-30

    ... to PISCO to take marine mammals incidental to these same proposed activities (77 FR 72327, December 5... National Oceanic and Atmospheric Administration RIN 0648-XC893 Takes of Marine Mammals Incidental to... Atmospheric Administration (NOAA), Commerce. ACTION: Notice; proposed incidental harassment...

  18. 78 FR 77433 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-23

    ... to PISCO to take marine mammals incidental to these same proposed activities (77 FR 72327, December 5... National Oceanic and Atmospheric Administration RIN 0648-XC893 Takes of Marine Mammals Incidental to... Atmospheric Administration (NOAA), Commerce. ACTION: Notice; proposed incidental harassment...

  19. NLR activation takes a direct route.

    PubMed

    Monie, Tom P

    2013-03-01

    For the first time there is now clear biochemical and biophysical evidence indicating that members of the nucleotide-binding domain and leucine-rich repeat containing (NLR) family can be activated as a result of direct interaction between the receptor and ligand. NLRX1 leucine-rich repeats bind to RNA; murine NAIP (NLR family, apoptosis inhibitory protein) 5 binds flagellin directly; and NOD (nucleotide-binding oligomerization domain containing) 1 and NOD2 may interact directly with fragments of peptidoglycan. It remains to be seen if NLRP3 has a specific ligand, but progress has been made in addressing its mechanism of activation, with cellular imbalances and mitochondrial dysfunction being important. This review updates our understanding of NLR activation in light of these recent advances and their impact on the NLR research. PMID:23394939

  20. Healthy youth places promoting nutrition and physical activity.

    PubMed

    Dzewaltowski, David A; Estabrooks, Paul A; Johnston, Judy A

    2002-10-01

    To reduce the risk for chronic disease, adolescents should eat at least five servings of fruit and vegetables and be physically active daily. The Healthy Youth Places Project will test if an intervention strategy that implements school environmental change--with adult leader and youth participation--will influence and maintain adolescent fruit and vegetable consumption and physical activity. Using an experimental design, middle schools will be randomized (eight intervention and eight control schools), and the health behavior of a cohort of adolescents will be assessed during Grades 6 (baseline), 7 and 8 (intervention), and 9 (follow-up). The project uses an ecologically informed social cognitive model to inform a place-based intervention that encourages participation in the process of planning and implemented environmental change in targeted adolescent physical and social environments (school lunch place and after school program place). Environmental change is defined as implemented practices, programs and policies that promote critical elements (connection, autonomy, skill-building and healthy norms) in places. These critical elements are hypothesized environmental antecedents of social cognitive mediators of behavior change. The Project develops a place-based dissemination model of multiple levels (project, school and place) that are hypothesized to build the skills and efficacy of leaders (school staff and youth) that implement environmental changes. PMID:12408199

  1. 78 FR 28411 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-14

    ... Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to Marine Seismic... Marine Seismic Survey in the Chukchi Sea, Alaska AGENCY: National Marine Fisheries Service (NMFS... occur in the seismic survey area include nine cetacean species, beluga whale (Delphinapterus...

  2. Systemic analysis of desertification processes taking place in the Limpopo river basin

    NASA Astrophysics Data System (ADS)

    Messina, Mario; Attorre, Fabio; Vitale, Marcello

    2016-04-01

    Desertification and land degradation are phenomena that ranks among the greatest environmental challenges of our time. Desertification is a global issue, with serious implications worldwide for biodiversity, socio-economic stability and sustainable development. Biophysical indicators of land degradation and desertification, like Net Primary Productivity (NPP) and Total Ecosystem Respiration (Reco) were provided by remote sensing technology (MODIS). The study aims to evaluate the dynamical changes of NPP and Reco in the Limpopo river basin, a Southern African region that includes, Botswana, Mozambique, South Africa and Zimbabwe, during the time period 2001-2010. In particular, the relations between NPP, Reco, environmental, physiological and land use parameters have been widely investigated through the application of a new and powerful statistical classifier, the Random Forest Analysis (RFA), and a general non-linear model, the Response Surface Regression Model (GRM). RFA highlighted that Temperature is one of the most important predictors affecting NPP and Reco in the Limpopo river basin. Conversely, other environmental parameters like, Precipitation, Evapotranspiration and Vegetation cover rarely influence NPP and Reco. Our results provide information on desertification and land degradation phenomena and a first step for identifying practices to mitigate their negative impacts. However, it must be taken into account that NPP and Reco depend by a multitude of factors (e.g. human activities, socio-economic policies) and can vary in relation to spatial and temporal scale. In order to achieve a better understanding of land degradation and desertification processes, land use and socio-economic variables should be considered.

  3. 77 FR 12246 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-29

    ... the specified activities was issued to VanBlaricom on September 23, 2003 (68 FR 57427; October 3, 2003); the most recent of these was issued on January 18, 2008 (73 FR 4841; January 28, 2008), expiring... Specified Activities; Taking Marine Mammals Incidental to Abalone Research on San Nicolas Island,...

  4. 76 FR 330 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-04

    ... ringed seal (75 FR 77476) and a notice of proposed threatened and not warranted status for subspecies and distinct population segments of the bearded seal (75 FR 77496) in the Federal Register. Neither species is... Specified Activities; Taking Marine Mammals Incidental to Polar Bear Captures AGENCY: National...

  5. 77 FR 25829 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-01

    ... Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to Marine Seismic... Marine Seismic Survey in the Beaufort Sea, Alaska AGENCY: National Marine Fisheries Service (NMFS... only, incidental to a proposed 3- dimensional (3D) ocean bottom cable (OBC) seismic survey in...

  6. 78 FR 35851 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-14

    ... encouraged to review NMFS' response to comments on this matter found in 69 FR 74906 (December 14, 2004), 71 FR 43112 (July 31, 2006), 71 FR 50027 (August 24, 2006), and 71 FR 49418 (August 23, 2006). It should... Specified Activities; Taking Marine Mammals Incidental to Marine Seismic Survey in the Beaufort Sea,...

  7. LIDAR for remote sensing of contaminations on water and earth surfaces taking place during oil-gas production

    NASA Astrophysics Data System (ADS)

    Pashayev, A.; Tagiyev, B.; Allahverdiyev, K.; Musayev, A.; Sadikhov, I.

    2015-12-01

    Remote sensing of contaminations on water and earth surfaces (oil spills, films) taking place during oil-gas extraction is an interesting and actual problem. This problem may be solved by using different methods of optical spectroscopy, including: •Raman scattering; •light induced breakdown spectroscopy (LIBS); •fluorescence spectroscopy. Fluorescence Light Detection and Ranging (LIDAR) LIDARs are successfully used for remote sensing of chemical and biological substances at atmosphere. A new laser induced fluorescence (LIF) KA-14 LIDAR system for detecting of oil spills on the sea surface was employed at the National Aviation Academy of Azerbaijan. LIDAR's parameters are as follows: •laser CFR 200- type QUANTEL, λ = 355 nm, beam Ø = 5.35 mm, f = 20 Hz, pulse duration τ = 7 ns, pulse power 60 mJ; •diameter of Newtonian- type telescope is 200 mm; •collimator expansion of the laser beam diameter- not less than 3; •angle range of telescope measurements relative to horizon: from -20 to +20 degree; •spectral range of measurements: from 380 to 750 nm, number of spectral channels- 32; •maximum range of measurements- not less than 250 m. This LIDAR is the first performing these kind of research not only on the Azerbaijan beach of Caspian sea, but also on the earth places of Absheron peninsula, where oil-gas production takes place. We hope that the performance of LIDAR will have an International recognition and will make noticeable input on the International Research of Caspian sea surfaces.

  8. 25 CFR 1000.465 - May a Tribe/Consortium negotiate AFA provisions on conflicts of interest to take the place of...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... conflicts of interest to take the place of this subpart? 1000.465 Section 1000.465 Indians OFFICE OF THE... § 1000.465 May a Tribe/Consortium negotiate AFA provisions on conflicts of interest to take the place of... example, the Tribe/Consortium and the Secretary may agree that using the Tribe's/Consortium's own...

  9. 25 CFR 1000.465 - May a Tribe/Consortium negotiate AFA provisions on conflicts of interest to take the place of...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... conflicts of interest to take the place of this subpart? 1000.465 Section 1000.465 Indians OFFICE OF THE... § 1000.465 May a Tribe/Consortium negotiate AFA provisions on conflicts of interest to take the place of... example, the Tribe/Consortium and the Secretary may agree that using the Tribe's/Consortium's own...

  10. 25 CFR 1000.465 - May a Tribe/Consortium negotiate AFA provisions on conflicts of interest to take the place of...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... conflicts of interest to take the place of this subpart? 1000.465 Section 1000.465 Indians OFFICE OF THE... § 1000.465 May a Tribe/Consortium negotiate AFA provisions on conflicts of interest to take the place of... example, the Tribe/Consortium and the Secretary may agree that using the Tribe's/Consortium's own...

  11. 25 CFR 1000.465 - May a Tribe/Consortium negotiate AFA provisions on conflicts of interest to take the place of...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... conflicts of interest to take the place of this subpart? 1000.465 Section 1000.465 Indians OFFICE OF THE... § 1000.465 May a Tribe/Consortium negotiate AFA provisions on conflicts of interest to take the place of... example, the Tribe/Consortium and the Secretary may agree that using the Tribe's/Consortium's own...

  12. The intersection of gender and place in online health activities.

    PubMed

    Goldner, Melinda; Hale, Timothy M; Cotten, Shelia R; Stern, Michael J; Drentea, Patricia

    2013-01-01

    This study examines how rurality and gender are related to online health activities. Rural women face greater health risks and yet have access to a weaker health system infrastructure, which has resulted in a health disadvantage. New health information technologies may ameliorate some of these disparities; thus, the authors examine the relevance of gender and place in going online to search for health information, buy medicines, participate in health-related support groups, communicate with physicians, or maintain a personal health record. Analyzing data from the National Cancer Institute's 2007 Health Information National Trends Survey, the authors found that the relations between rurality and gender vary, depending on the specific type of online health activity, and that gender may be a more salient factor than rurality in determining whether individuals engage in particular types of online health activities. This study contributes to the literature by examining how gender and place are related to online health activities, a combined area neglected in past research, and advancing research on gender and technology. This research highlights the importance of expanding high-speed access in rural locations, increasing technological and health literacy, and tailoring the Internet to specific populations. PMID:23886026

  13. Street Smarts: Activities That Help Teenagers Take Care of Themselves.

    ERIC Educational Resources Information Center

    Kirby, Michael

    Because growing up has become the art of survival for many young people, a professionally conducted course in street smarts can help them identify problems, understand consequences, and make good decisions. The information and activities contained in this text can teach students how to take care of themselves when confronted with challenges. It…

  14. Taking into account photofission effects in gamma-activation analysis

    SciTech Connect

    Dayvdov, M.G.; Kishel'gof, V.V.; Naumov, A.P.; Trukhov, A.V.

    1986-11-01

    The authors proposed a method for calculating the effect of photofission of U and Th, which is based on the well-known laws of physics of photofission and methods for calculating the activity of fission products. The authors compared the results of numerical calculations of the gamma spectra of photofission products with the measurements performed with a Ge (Li) detector with the spectra from activated model samples of U and Th. The method developed enables calculating the coefficients of interference and is also applicable to the solution of the problems of optimization of gamma activation analysis taking into account U and Th fission.

  15. 77 FR 49921 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-17

    ... from ION Geophysical (ION) for an Incidental Harassment Authorization (IHA) to take marine mammals, by... comments on its proposal to issue an IHA to ION to take, by harassment, nine species of marine mammals... March 1, 2012, from ION for the taking, by harassment, of marine mammals incidental to a marine...

  16. 49 CFR 40.41 - Where does a urine collection for a DOT drug test take place?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... used for adulteration and substitution (e.g., water faucets, soap dispensers) and providing moist... could be used for adulteration and substitution (e.g., water faucets, soap dispensers) and place...

  17. 76 FR 68973 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-07

    ...NMFS received an application from Shell Offshore Inc. (Shell) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to offshore exploration drilling on Outer Continental Shelf (OCS) leases in the Beaufort Sea, Alaska. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on its proposal to issue an IHA to Shell to take, by......

  18. 78 FR 12541 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-22

    ...NMFS received an application from ConocoPhillips Company (COP) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to offshore exploration drilling on Outer Continental Shelf (OCS) leases in the Chukchi Sea, Alaska. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on its proposal to issue an IHA to COP to take, by......

  19. 75 FR 25729 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ...NMFS received an application from Shell Offshore Inc. (Shell) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to offshore exploration drilling on Outer Continental Shelf (OCS) leases in the Chukchi Sea, Alaska. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on its proposal to issue an IHA to Shell to take, by......

  20. 75 FR 20481 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-19

    ...NMFS received an application from Shell Offshore Inc. (Shell) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to offshore exploration drilling on Outer Continental Shelf (OCS) leases in the Beaufort Sea, Alaska. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on its proposal to issue an IHA to Shell to take, by......

  1. 76 FR 69957 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-09

    ...NMFS received an application from Shell Offshore Inc. (Shell) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to offshore exploration drilling on Outer Continental Shelf (OCS) leases in the Chukchi Sea, Alaska. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on its proposal to issue an IHA to Shell to take, by......

  2. 76 FR 58473 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-21

    ...NMFS received an application from Apache Alaska Corporation (Apache) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to a proposed 3D seismic survey in Cook Inlet, Alaska, between November 2011 and November 2012. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS requests comments on its proposal to issue an IHA to Apache to take, by......

  3. 77 FR 51773 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-27

    ...NMFS has received an application from the U.S. Fish and Wildlife Service (USFWS) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to a bird mitigation research trial in the Farallon National Wildlife Refuge. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on its proposal to issue an IHA to the USFWS to take, by......

  4. 23 CFR 636.401 - What types of information exchange may take place prior to the release of the RFP document?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false What types of information exchange may take place prior to the release of the RFP document? 636.401 Section 636.401 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING Exchanges §...

  5. 25 CFR 1000.465 - May a Tribe/Consortium negotiate AFA provisions on conflicts of interest to take the place of...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false May a Tribe/Consortium negotiate AFA provisions on conflicts of interest to take the place of this subpart? 1000.465 Section 1000.465 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE...

  6. 78 FR 24731 - Taking Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to an...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-26

    ...Notice is hereby given that ConocoPhillips Company (COP) has withdrawn its application for an Incidental Harassment Authorization (IHA). The following action is related to a proposed IHA to COP for the take of small numbers of marine mammals, by Level B harassment, incidental to conducting offshore exploration drilling on Outer Continental Shelf (OCS) leases in the Chukchi Sea, Alaska, during......

  7. 77 FR 50990 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-23

    ...NMFS has received an application from the National Ocean Service's Office of National Marine Sanctuaries Gulf of the Farallones National Marine Sanctuary (GFNMS) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to rocky intertidal monitoring work and searching for black abalone, components of the Sanctuary Ecosystem Assessment Surveys. Pursuant......

  8. 75 FR 49709 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-13

    ...In accordance with the Marine Mammal Protection Act (MMPA) regulations, notification is hereby given that NMFS has issued an Incidental Harassment Authorization (IHA) to Shell Offshore Inc. (Shell) to take, by harassment, small numbers of 8 species of marine mammals incidental to a marine survey program, which includes site clearance and shallow hazards, ice gouge, and strudel scour surveys,......

  9. 77 FR 64320 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-19

    ... National Oceanic and Atmospheric Administration RIN 0648-XC283 Takes of Marine Mammals Incidental to... Atmospheric Administration (NOAA), Commerce. ACTION: Notice; proposed incidental harassment authorization... and to determine if any relationship exists between changing ocean chemistry and the states of two...

  10. 78 FR 52135 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-22

    ... AFB, published in the Federal Register on June 4, 2013 (78 FR 33357). During the 30-day public comment... mammal takes was fully explained in the IHA application, the Notice of Proposed IHA (78 FR 33357, June 4... which involved large explosives (65 FR 77546; December 12, 2000). Because no large explosives...

  11. 78 FR 35507 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-12

    ...NMFS received an application from TGS-NOPEC Geophysical Company ASA (TGS) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment only, incidental to a marine 2- dimensional (2D) seismic survey program in the Chukchi Sea, Alaska, during the open water season of 2013. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on its proposal......

  12. 77 FR 40007 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-06

    ...In accordance with the Marine Mammal Protection Act (MMPA) regulations, notification is hereby given that NMFS has issued an Incidental Harassment Authorization (IHA) to BP Exploration (Alaska), Inc. (BP) to take, by harassment, small numbers of 10 species of marine mammals incidental to ocean bottom cable (OBC) seismic surveys in the Simpson Lagoon area of the Beaufort Sea, Alaska, during the......

  13. 78 FR 51147 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-20

    ...In accordance with the Marine Mammal Protection Act (MMPA) regulations, notification is hereby given that NMFS has issued an Incidental Harassment Authorization (IHA) to TGS-NOPEC Geophysical Company ASA (TGS) to take, by harassment, small numbers of marine mammals incidental to a marine 2-dimensional (2D) seismic survey program in the Chukchi Sea, Alaska, during the 2013 Arctic open-water......

  14. 76 FR 4300 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-25

    ...NMFS has received an application from the U.S. Navy (Navy) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to pile driving activities as part of a test pile program. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on its proposal to issue an IHA to the Navy to take, by Level B Harassment only, five species of......

  15. 78 FR 30873 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ...NMFS has received an application from the U.S. Navy (Navy) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to construction activities as part of a pier replacement project. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on its proposal to issue an IHA to the Navy to take, by Level B Harassment only, four......

  16. Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 in lipopolysaccharide-stimulated RAW264.7 cells by carboxybutyrylated glucosamine takes place via down-regulation of mitogen-activated protein kinase-mediated nuclear factor-κB signaling

    PubMed Central

    Rajapakse, Niranjan; Kim, Moon-Moo; Mendis, Eresha; Kim, Se-Kwon

    2008-01-01

    Glucosamine (GlcN) has been reported to possess several biomedical properties, and currently a great deal of attention has been focused on improving the functional properties of GlcN for different applications. Therefore, this study was conducted to introduce a carboxybutyryl functional group to GlcN and to find out the inhibitory mechanism of a novel GlcN derivative, carboxybutyrylated GlcN (CGlcN), on the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in bacterial lipopolysaccharide (LPS)-induced mouse macrophages (RAW264.7 cells). In the initial experiments, the production of NO and prostaglandin E2 (PGE2) was inhibited by CGlcN pretreatment and suggested the possibility of down-regulating their respective genes, iNOS and COX-2. Reverse transcription-polymerase chain reaction and Western blot analysis revealed that CGlcN can affect both transcriptional and translational levels of iNOS and COX-2 expression. The data from the nuclear factor-κB (NF-κB) promoter gene transfection experiment supported the idea that inhibition of iNOS and COX-2 is caused by the down-regulation of their transcription factor, NF-κB. Following stimulation with LPS, p38 mitogen-activated protein kinase (p38 MAPK) and c-Jun N-terminal kinase (JNK) present upstream of NF-κB signaling were also inhibited by CGlcN treatment. However, the protein level of another MAPK, extracellular signal-regulated kinase (ERK), remained unaffected. Moreover, following treatment with CGlcN, the protein expression of I-κB kinase (IKK) clearly confirmed that its down-regulation directly inhibited the degradation of IκB and release of NF-κB. Therefore, it can be concluded that CGlcN is capable of inhibiting iNOS and COX-2 expression in LPS-induced RAW264.7 cells via attenuation of NF-κB signaling by p38 MAPK and JNK, but not by ERK. PMID:18205790

  17. 75 FR 5045 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-01

    ... issuance of an IHA for Eglin's Precision Strike Weapon testing activity (70 FR 48675, August 19, 2005) and... IHA and request for 30-day public comment published on January 23, 2006 (71 FR 3474). A 1-year IHA was subsequently issued to Eglin AFB for this activity on May 3, 2006 (71 FR 27695, May 12, 2006). On January...

  18. Placing the power of real options analysis into the hands of natural resource managers - taking the next step.

    PubMed

    Nelson, Rohan; Howden, Mark; Hayman, Peter

    2013-07-30

    This paper explores heuristic methods with potential to place the analytical power of real options analysis into the hands of natural resource managers. The complexity of real options analysis has led to patchy or ephemeral adoption even by corporate managers familiar with the financial-market origins of valuation methods. Intuitively accessible methods for estimating the value of real options have begun to evolve, but their evaluation has mostly been limited to researcher-driven applications. In this paper we work closely with Bush Heritage Australia to evaluate the potential of real options analysis to support the intuitive judgement of conservation estate managers in covenanting land with uncertain future conservation value due to climate change. The results show that modified decision trees have potential to estimate the option value of covenanting individual properties while time and ongoing research resolves their future conservation value. Complementing this, Luehrman's option space has potential to assist managers with limited budgets to increase the portfolio value of multiple properties with different conservation attributes. PMID:23702285

  19. 26 CFR 1.924(d)-1 - Requirement that economic processes take place outside the United States.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... United States. If the person who performed the activity on behalf of the FSC is an independent contractor... variable contract terms, such as price, credit terms, quantity, or time or manner of delivery, or specifies... new price. The written confirmation by the FSC of an oral agreement on a variable contract...

  20. 26 CFR 1.924(d)-1 - Requirement that economic processes take place outside the United States.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... United States. If the person who performed the activity on behalf of the FSC is an independent contractor... variable contract terms, such as price, credit terms, quantity, or time or manner of delivery, or specifies... new price. The written confirmation by the FSC of an oral agreement on a variable contract...

  1. The Learner, the Media and the Community: How Does Learning Take Place in the Other CALL Triangle?

    ERIC Educational Resources Information Center

    Sockett, Geoffrey

    2012-01-01

    In this research project, students in applied linguistics were asked to keep blogs over a three-month period in which they reported on their online informal learning of English through activities such as social networking, downloading films and TV series and listening to music on demand. The study is situated within the framework of complexity…

  2. 78 FR 70921 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... Steller sea lions (78 FR 66139). We have determined that this DPS has recovered and no longer meets the... Geographic Location and Activity Timeframe The Farallon Islands consists of a chain of seven islands...

  3. 12 CFR 14.50 - Where insurance activities may take place.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ....50 Section 14.50 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY CONSUMER... transactions are routinely conducted in the bank may refer a consumer who seeks to purchase an insurance product or annuity to a qualified person who sells that product only if the person making the...

  4. 12 CFR 208.85 - Where insurance activities may take place.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SYSTEM MEMBERSHIP OF STATE BANKING INSTITUTIONS IN THE FEDERAL RESERVE SYSTEM (REGULATION H) Consumer... receives no more than a one-time, nominal fee of a fixed dollar amount for each referral that does...

  5. 77 FR 65059 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-24

    ... FR 49922). That notice described, in detail, ION's proposed activity, the marine mammal species that... Register notice for the proposed IHA (77 FR 49922; August 17, 2012), ION would start its seismic survey... proposed IHA (77 FR 49922; August 17, 2012), ION's in-ice seismic survey would be performed in a...

  6. 76 FR 43639 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-21

    ... construction and operation of the NEG Port and the Algonquin Pipeline Lateral (72 FR 27077; May 14, 2007... NEG Port activity pursuant to section 101(a)(5)(D) of the MMPA (73 FR 29485; May 21, 2008; 74 FR 45613; September 3, 2009, and 75 FR 53672; September 1, 2010). The current IHA expires on August 30,...

  7. 78 FR 79403 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-30

    ... proposal and preliminary determinations (78 FR 64918). The notice initiated a 30-day public comment period... incidental to these same proposed activities (77 FR 72327, December 5, 2012). That IHA expired on December 2... ADDRESSES) and the Notice of Proposed IHA (78 FR 64918, October 30, 2013). Community Structure...

  8. 76 FR 46729 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ... in the Federal Register notice for the proposed IHA (76 FR 30110; May 24, 2011). That information has... (including operating frequencies and estimated source levels) of all active sources, as well as the sounds... IHA (76 FR 30110; May 24, 2011). That information has not changed and is therefore not repeated...

  9. 76 FR 43267 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-20

    ... Notice of Proposed IHA and request for 30-day public comment published on January 23, 2006 (71 FR 3474). A 1-year IHA was subsequently issued to Eglin AFB for ] this activity on May 3, 2006 (71 FR 27695.... A Notice of Proposed IHA and request for 30-day public comment published on May 30, 2007 (72...

  10. 77 FR 27720 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-11

    ... notice in the Federal Register (76 FR 58473) discussing the effects on marine mammals and making... the proposed IHA (76 FR 58473, September 21, 2011). The activities to be conducted have not changed... should refer to the proposed IHA notice (76 FR 58473, September 21, 2011), the IHA application...

  11. 76 FR 9250 - Taking of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-17

    ... for this activity, which was published in the Federal Register on Tuesday, July 14, 2009 (74 FR 33960... action contained in the proposed rule (74 FR 33960; July 14, 2009; pages 33961-33962) has not changed... Table 1 of the proposed rule (74 FR 33960; July 14, 2009; page 33962). This change was to correct...

  12. 77 FR 68107 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-15

    ... preliminary determinations and explained the basis for the proposal and preliminary determinations (77 FR... the Notice of Proposed IHA (77 FR 50990, August 23, 2012). Routine shore activity will continue to... additional information on the survey methodology (77 FR 50990, August 23, 2012). That information has...

  13. 78 FR 47495 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ... Register on May 14, 2012 (78 FR 28412). That notice described, in detail, Shell's proposed activity, the... serious injury (60 FR 28381, May 31, 1995). A private citizen further states that the marine survey is... limited to only those that may involve non-serious injury (60 FR 28379; May 31, 1995). While the...

  14. 76 FR 13453 - Marine Mammals; Incidental Take During Specified Activities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-11

    ...The Fish and Wildlife Service (Service) proposes regulations that would authorize the nonlethal, incidental, unintentional take of small numbers of polar bears and Pacific walruses during year-round oil and gas industry (Industry) exploration, development, and production operations in the Beaufort Sea and adjacent northern coast of Alaska. Industry operations for the covered period are similar......

  15. 78 FR 1941 - Marine Mammals; Incidental Take During Specified Activities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-09

    ...In accordance with the Marine Mammal Protection Act of 1972, as amended (MMPA), and its implementing regulations, we, the U.S. Fish and Wildlife Service (Service or we), propose regulations that authorize the nonlethal, incidental, unintentional take of small numbers of Pacific walruses (Odobenus rosmarus divergens) and polar bears (Ursus maritimus) during oil and gas industry (Industry)......

  16. 77 FR 60109 - Takes of Marine Mammals Incidental to Specified Activities; Harbor Activities Related to the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-02

    ...In accordance with the Marine Mammal Protection Act (MMPA) regulations, notification is hereby given that NMFS has issued an Incidental Harassment Authorization (IHA) to United Launch Alliance (ULA), to take marine mammals, by Level B harassment, incidental to conducting Delta Mariner activities related to the Delta IV/Evolved Expendable Launch Vehicle (Delta IV/EELV) at south Vandenberg Air......

  17. Understanding the structural changes that take place in a polypyrrole film during its oxi-reduction process: a molecular dynamics simulation study

    NASA Astrophysics Data System (ADS)

    Lopez Cascales, J. J.; Otero, T. F.

    2005-06-01

    Oxi-reduction processes of conducting polymer are the base of a great number of technological developments in the fields of polymeric actuators (artificial muscles) or smart windows. Hence, the understanding the structural changes that take place in the polymer as a function of its oxidation seems to be crucial for a proper understanding of these complicated systems. In this sense, a model with atomic detail has been simulated by Molecular Dynamics Simulation, which provides an insight of how the electrical response of the system depends of the structural changes that take place inside the polymer. In this regard, the conducting polymer, water and counterions were modeled with atomic detail with the goal of obtaining an insight of the ring orientation and reorientational relaxation time of the pyrrole rings at different oxidation states of the polymer. In addition, we studied how the above properties are greatly affected by the oxidation state of the polymer and the variation these properties changes from the polypyrrole/water interface to the polypyrrole bulk. Finally, we correlated the reorientational dynamics of pyrrole rings with the oxidation kinetic observed from a macroscopic point of view.

  18. 77 FR 2350 - Agency Information Collection (Request for Change of Program or Place of Training): Activity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-17

    ....Regulations.gov or to VA's OMB Desk Officer, OMB Human Resources and Housing Branch, New Executive Office... AFFAIRS Agency Information Collection (Request for Change of Program or Place of Training): Activity Under... INFORMATION: Title: Request for Change of Program or Place of Training, VA Form 22-1995. OMB Control...

  19. 78 FR 34669 - Incidental Take Permit and Environmental Assessment for Forest Management Activities, Southern...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-10

    ... Fish and Wildlife Service Incidental Take Permit and Environmental Assessment for Forest Management... of a proposed habitat conservation plan (HCP) and accompanying documents for proposed forest management activities by Potlatch Forest Holdings, Inc. (Applicant) that would take the endangered...

  20. It Takes a Virtual Community: Promoting Collaboration through Student Activities

    ERIC Educational Resources Information Center

    Battista, Ludmila; Forrey, Carol; Stevenson, Carolyn

    2008-01-01

    Distance education provides many nontraditional students with the opportunity to pursue a college education not possible through traditional brick and mortar education. Although not meeting face-to-face, student activities help promote a stronger connection between the classroom and university community. This paper will discuss strategies for…

  1. 75 FR 79342 - Taking and Importing Marine Mammals; Navy Training Activities Conducted Within the Northwest...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... preamble to the final rule (75 FR 69296, November 10, 2010), that the taking resulting from the activities... findings, described in the preamble to the final rule (75 FR 45527, August 3, 2010), that the taking... detonations at levels that NMFS associates with the take of marine mammals. The Navy's model, which did...

  2. STS-100 crew takes part in TCDT activities

    NASA Technical Reports Server (NTRS)

    2001-01-01

    KENNEDY SPACE CENTER, Fla. - STS-100 Mission Specialist Chris Hadfield pauses for the camera during Terminal Countdown Demonstration Test activities that include emergency escape training at the pad and a simulated launch countdown. The mission is carrying the Multi-Purpose Logistics Module Raffaello and the Canadian robotic arm, SSRMS, to the International Space Station. Raffaello carries six system racks and two storage racks for the U.S. Lab. The SSRMS is crucial to the continued assembly of the orbiting complex. Launch of mission STS-100 is scheduled for April 19 at 2:41 p.m. EDT from Launch Pad 39A.

  3. STS-113 crew members take part in CEIT activities

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. - As part of Crew Equipment Interface Test activities, STS-113 Mission Specialists Michael Lopez-Alegria (left) and John Herrington (center) look over equipment that will be carried on the mission. The primary payloads on mission STS-113 are the first port truss segment, P1 Truss, to be attached to the central truss segment, S0, on the International Space Station, and the Crew and Equipment Translation Aid (CETA) Cart B that can be used by spacewalkers to move along the truss with equipment. Once delivered, the P1 truss will remain stowed until flight 12A.1. The mission will also deliver the Expedition 6 crew to the Station and return Expedition 5 to Earth. Space Shuttle Endeavour is scheduled to launch Nov. 10 on the 11-day mission.

  4. STS-100 crew takes part in TCDT activities

    NASA Technical Reports Server (NTRS)

    2001-01-01

    KENNEDY SPACE CENTER, Fla. - KSC'''s PAO videographer, Glenn Benson (left) and STS-100 Pilot Jeffrey S. Ashby pose in front of the Canadian robotic arm, SSRMS, in the Space Station Processing Facility. The STS-100 crew is at KSC for Terminal Countdown Demonstration Test activities that include emergency escape training at the pad and a simulated launch countdown. The mission is carrying the Multi-Purpose Logistics Module Raffaello and the SSRMS, to the International Space Station. Raffaello carries six system racks and two storage racks for the U.S. Lab. The SSRMS is crucial to the continued assembly of the orbiting complex. Launch of mission STS-100 is scheduled for April 19 at 2:41 p.m. EDT from Launch Pad 39A.

  5. STS-100 crew takes part in TCDT activities

    NASA Technical Reports Server (NTRS)

    2001-01-01

    KENNEDY SPACE CENTER, Fla. - The STS-100 crew gathers at the bus when Terminal Countdown Demonstration Test activities are hampered by the rain. Standing with the bus driver, from left, are Mission Specialist John L. Phillips, Commander Kent V. Rominger, Mission Specialists Umberto Guidoni, Chris Hadfield, [driver], and Scott E. Parazynski, Pilot Jeffrey S. Ashby and Mission Specialist Yuri V. Lonchakov. TCDT includes emergency escape training at the pad and a simulated launch countdown. The mission is carrying the Multi-Purpose Logistics Module Raffaello and the Canadian robotic arm, SSRMS, to the International Space Station. Raffaello carries six system racks and two storage racks for the U.S. Lab. The SSRMS is crucial to the continued assembly of the orbiting complex. Launch of mission STS-100 is scheduled for April 19 at 2:41 p.m. EDT from Launch Pad 39A.

  6. STS-113 crew members take part in CEIT activities

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- As part of Crew Equipment Interface Test activities, STS-113 Mission Specialists John Herrington (left) and Michael Lopez-Alegria (center) practice working with equipment in Endeavour. The primary payloads on mission STS-113 are the first port truss segment, P1 Truss, to be attached to the central truss segment, S0, on the International Space Station, and the Crew and Equipment Translation Aid (CETA) Cart B that can be used by spacewalkers to move along the truss with equipment. Once delivered, the P1 truss will remain stowed until flight 12A.1. The mission will also deliver the Expedition 6 crew to the Station and return Expedition 5 to Earth. Space Shuttle Endeavour is scheduled to launch Nov. 10 on the 11-day mission.

  7. STS-113 crew members take part in CEIT activities

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- As part of Crew Equipment Interface Test activities, STS-113 Mission Specialists Michael Lopez-Alegria (left) and John Herrington (right) practice working with flight equipment in Endeavour. The primary payloads on mission STS-113 are the first port truss segment, P1 Truss, to be attached to the central truss segment, S0, on the International Space Station, and the Crew and Equipment Translation Aid (CETA) Cart B that can be used by spacewalkers to move along the truss with equipment. Once delivered, the P1 truss will remain stowed until flight 12A.1. The mission will also deliver the Expedition 6 crew to the Station and return Expedition 5 to Earth. Space Shuttle Endeavour is scheduled to launch Nov. 10 on the 11-day mission.

  8. STS-100 crew takes part in TCDT activities

    NASA Technical Reports Server (NTRS)

    2001-01-01

    KENNEDY SPACE CENTER, Fla. - KSC'''s PAO videographer, Glenn Benson (left) listens to STS-100 Pilot Jeffrey S. Ashby explain use of the Canadian robotic arm, SSRMS (left), in the Space Station Processing Facility. At right is Mission Specialist Umberto Guidoni. The STS-100 crew is at KSC for Terminal Countdown Demonstration Test activities that include emergency escape training at the pad and a simulated launch countdown. The mission is carrying the Multi-Purpose Logistics Module Raffaello and the SSRMS, to the International Space Station. Raffaello carries six system racks and two storage racks for the U.S. Lab. The SSRMS is crucial to the continued assembly of the orbiting complex. Launch of mission STS-100 is scheduled for April 19 at 2:41 p.m. EDT from Launch Pad 39A.

  9. STS-113 crew members take part in CEIT activities

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- As part of Crew Equipment Interface Test activities, STS-113 Mission Specialist John Herrington looks over paperwork for equipment in Endeavour that will be carried on the mission. The primary payloads on mission STS-113 are the first port truss segment, P1 Truss, to be attached to the central truss segment, S0, on the International Space Station, and the Crew and Equipment Translation Aid (CETA) Cart B that can be used by spacewalkers to move along the truss with equipment. Once delivered, the P1 truss will remain stowed until flight 12A.1. The mission will also deliver the Expedition 6 crew to the Station and return Expedition 5 to Earth. Space Shuttle Endeavour is scheduled to launch Nov. 10 on the 11-day mission.

  10. STS-100 crew takes part in TCDT activities

    NASA Technical Reports Server (NTRS)

    2001-01-01

    KENNEDY SPACE CENTER, Fla. - The STS-100 crew gathers with the Space Station Processing Facility people who worked on the Canadian robotic arm, SSRMS. Kneeling at left is Commander Kent V. Rominger; front and ceneter, from left, Mission Specialist Chris Hadfield, Pilot Jeffrey S. Ashby and Mission Specialists Yuri V. Lonchakov and John L. Phillips; behind Hadfield (a head above the others) is Mission Specialist Scott E. Parazynski. The crew is at KSC for Terminal Countdown Demonstration Test activities that include emergency escape training at the pad and a simulated launch countdown. The mission is carrying the Multi- Purpose Logistics Module Raffaello and the SSRMS, to the International Space Station. Raffaello carries six system racks and two storage racks for the U.S. Lab. The SSRMS is crucial to the continued assembly of the orbiting complex. Launch of mission STS-100 is scheduled for April 19 at 2:41 p.m. EDT from Launch Pad 39A.

  11. Place-Based Science Teaching and Learning: 40 Activities for K-8 Classrooms

    ERIC Educational Resources Information Center

    Buxton, Cory A.; Provenzo, Eugene F., Jr.

    2011-01-01

    Grounded in theory and best-practices research, this practical text provides elementary and middle school teachers with 40 place-based activities that will help them to make science learning relevant to their students. This text provides teachers with both a rationale and a set of strategies and activities for teaching science in a local context…

  12. Prenatal immune activation alters hippocampal place cell firing characteristics in adult animals.

    PubMed

    Wolff, Amy R; Bilkey, David K

    2015-08-01

    Prenatal maternal immune activation (MIA) is a risk factor for several developmental neuropsychiatric disorders, including autism, bipolar disorder and schizophrenia. Adults with these disorders display alterations in memory function that may result from changes in the structure and function of the hippocampus. In the present study we use an animal model to investigate the effect that a transient prenatal maternal immune activation episode has on the spatially-modulated firing activity of hippocampal neurons in adult animals. MIA was induced in pregnant rat dams with a single injection of the synthetic cytokine inducer polyinosinic:polycytidylic acid (poly I:C) on gestational day 15. Control dams were given a saline equivalent. Firing activity and local field potentials (LFPs) were recorded from the CA1 region of the adult male offspring of these dams as they moved freely in an open arena. Most neurons displayed characteristic spatially-modulated 'place cell' firing activity and while there was no between-group difference in mean firing rate between groups, place cells had smaller place fields in MIA-exposed animals when compared to control-group cells. Cells recorded in MIA-group animals also displayed an altered firing-phase synchrony relationship to simultaneously recorded LFPs. When the floor of the arena was rotated, the place fields of MIA-group cells were more likely to shift in the same direction as the floor rotation, suggesting that local cues may have been more salient for these animals. In contrast, place fields in control group cells were more likely to shift firing position to novel spatial locations suggesting an altered response to contextual cues. These findings show that a single MIA intervention is sufficient to change several important characteristics of hippocampal place cell activity in adult offspring. These changes could contribute to the memory dysfunction that is associated with MIA, by altering the encoding of spatial context and by

  13. More than Activities: Using a "Sense of Place" to Enrich Student Experience in Adventure Sport

    ERIC Educational Resources Information Center

    Leather, Mark; Nicholls, Fiona

    2016-01-01

    There has been increasing interest in recent years in the significance of a sense of place in the literature of outdoor adventure education. In the UK relationships between outdoor education and the environment still appear largely focused on the science of the natural environment and the activity in question. In this paper, we present empirical…

  14. Place as Text: Approaches to Active Learning. 2nd Edition. National Collegiate Honors Council Monograph Series

    ERIC Educational Resources Information Center

    Braid, Bernice, Ed.; Long, Ada, Ed.

    2010-01-01

    The decade since publication of "Place as Text: Approaches to Active Learning" has seen an explosion of interest and productivity in the field of experiential education. This monograph presents a story of an experiment and a blueprint of sorts for anyone interested in enriching an existing program or willing to experiment with pedagogy…

  15. Take-Home Challenges: Extending Discovery-Based Activities beyond the General Chemistry Classroom

    NASA Astrophysics Data System (ADS)

    Mason, P. K.; Sarquis, A. M.

    1996-04-01

    In an effort to more effectively integrate the experimental nature of chemistry into our students' experiences, we are developing and implementing discovery-based activities into both the laboratory and lecture components of general chemistry. Below we describe and provide an example of a "take-home challenge" intended to supplement the lecture component of the course. These take-home challenges involve the student in chemistry exploration outside of class and extend the context of content and experimentation into a nontraditional laboratory environment. Over 25 take-home challenges have been developed to date. Preliminary evaluation of the impact of the take-home challenges shows that students reporting themselves as receiving a B or C grade in the course find the challenges very useful in helping them gain a conceptual understanding of the phenomena addressed. Students earning an A grade report little or no impact on their learning. Prepared as one-page handouts, each take-home challenge begins with a scene-setting introduction followed by pertinent background information, a list of materials to be collected, and any appropriate safety precautions. The exploration component of the activity integrates leading questions with the procedural instructions to help guide the students through the discovery process and challenge them to stretch their understanding of the chemistry. After completing a take-home challenge activity, students submit written reports containing responses to the questions posed, observations of data collected, and their responses to the challenge. The accompanying sample take-home challenge activity is provided as a novel adaptation of the belch phenomenon that challenges students to experiment in order to explain the factors that account for the observed behavior. Persons interested in field testing the take-home challenges with their classes should contact the authors. Belch Bottle Challenge: What factors are responsible for the behavior of a

  16. 50 CFR 21.15 - Authorization of take incidental to military readiness activities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Authorization of take incidental to military readiness activities. 21.15 Section 21.15 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF...

  17. 75 FR 78228 - Takes of Marine Mammals Incidental to Specified Activities; Columbia River Crossing Project...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-15

    ... authorization to take marine mammals incidental to bridge construction and demolition activities at the Columbia... existing North Portland Harbor Bridge, and construction of three new structures across the harbor; and... authorization for take of three species of marine mammals incidental to construction and demolition...

  18. Peers Increase Adolescent Risk Taking by Enhancing Activity in the Brain's Reward Circuitry

    ERIC Educational Resources Information Center

    Chein, Jason; Albert, Dustin; O'Brien, Lia; Uckert, Kaitlyn; Steinberg, Laurence

    2011-01-01

    The presence of peers increases risk taking among adolescents but not adults. We posited that the presence of peers may promote adolescent risk taking by sensitizing brain regions associated with the anticipation of potential rewards. Using fMRI, we measured brain activity in adolescents, young adults, and adults as they made decisions in a…

  19. Longitudinal Changes in Prefrontal Cortex Activation Underlie Declines in Adolescent Risk Taking

    PubMed Central

    Galvan, Adriana; Fuligni, Andrew J.; Lieberman, Matthew D.

    2015-01-01

    Adolescence is a critical developmental phase during which risk-taking behaviors increase across a variety of species, raising the importance of understanding how brain changes contribute to such behaviors. While the prefrontal cortex is thought to influence adolescent risk taking, the specific ways in which it functions are unclear. Using longitudinal functional magnetic resonance imaging in human adolescents, we found that ventrolateral prefrontal cortex (VLPFC) activation decreased during an experimental risk-taking task over time, with greater declines in VLPFC associated with greater declines in self-reported risky behavior. Furthermore, greater decreases in functional coupling between the medial prefrontal cortex (MPFC) and ventral striatum over time were associated with decreases in self-reported risky behavior. Thus, disparate roles of the VLPFC and MPFC modulate longitudinal declines in adolescent risk taking. SIGNIFICANCE STATEMENT Adolescence is a developmental period marked by steep increases in risk-taking behavior coupled with dramatic brain changes. Although theories propose that the prefrontal cortex (PFC) may influence adolescent risk taking, the specific ways in which it functions remain unclear. We report the first longitudinal functional magnetic resonance imaging study to examine how neural activation during risk taking changes over time and contributes to adolescents' real-life risk-taking behavior. We find that longitudinal declines in activation of the ventrolateral PFC are linked to declines in adolescent risk taking, whereas the medial PFC influences adolescent risk taking via its functional neural coupling with reward-related regions. This is the first study to identify the mechanism by which different regions of the PFC disparately contribute to declines in risk taking. PMID:26269638

  20. Local Field Potentials Encode Place Cell Ensemble Activation during Hippocampal Sharp Wave Ripples.

    PubMed

    Taxidis, Jiannis; Anastassiou, Costas A; Diba, Kamran; Koch, Christof

    2015-08-01

    Whether the activation of spiking cell ensembles can be encoded in the local field potential (LFP) remains unclear. We address this question by combining in vivo electrophysiological recordings in the rat hippocampus with realistic biophysical modeling, and explore the LFP of place cell sequence spiking ("replays") during sharp wave ripples. We show that multi-site perisomatic LFP amplitudes, in the ∼150-200 Hz frequency band, reliably reflect spatial constellations of spiking cells, embedded within non-spiking populations, and encode activation of local place cell ensembles during in vivo replays. We find spatiotemporal patterns in the LFP, which remain consistent between sequence replays, in conjunction with the ordered activation of place cell ensembles. Clustering such patterns provides an efficient segregation of replay events from non-replay-associated ripples. This work demonstrates how spatiotemporal ensemble spiking is encoded extracellularly, providing a window for efficient, LFP-based detection and monitoring of structured population activity in vivo. PMID:26247865

  1. 76 FR 79409 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-21

    .... Hydroacoustic monitoring results from the Navy's Test Pile Project (see 76 FR 38361; July 30, 2011) will be used... December 21, 2011 Part V Department of Commerce National Oceanic and Atmospheric Administration Takes of... Oceanic and Atmospheric Administration RIN 0648-XA830 Takes of Marine Mammals Incidental to...

  2. 78 FR 43165 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-19

    ... the Secretary of Commerce to allow, upon request, the incidental, but not intentional, taking of small... an authorization to incidentally take small numbers of marine mammals by harassment. Section 101(a)(5... Register notice of proposed authorization (78 FR 30273; May 22, 2013; hereafter, the FR notice); please...

  3. 76 FR 38361 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-30

    ... intentional, taking by harassment of small numbers of marine mammals of a species or population stock, by... provided to the public for review. Authorization for incidental taking of small numbers of marine mammals... incidental harassment of small numbers of marine mammals. Within 45 days of the close of the public...

  4. 78 FR 43148 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-19

    ... following parameters were considered: (1) Pile size and materials: Steel pipe piles (30-72 in diameter); (2... the Secretary of Commerce to allow, upon request, the incidental, but not intentional, taking of small... an authorization to incidentally take small numbers of marine mammals by harassment. Section...

  5. 77 FR 43049 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-23

    ... pipe pile removal (12- to 24-in diameter) and concrete pile removal with chipping hammer or similar... the Secretary of Commerce to allow, upon request, the incidental, but not intentional, taking of small... an authorization to incidentally take small numbers of marine mammals by harassment. Section...

  6. 78 FR 30273 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-22

    ... National Oceanic and Atmospheric Administration RIN 0648-XC647 Takes of Marine Mammals Incidental to... Fisheries Service (NMFS), National Oceanic and Atmospheric Administration (NOAA), Commerce. ACTION: Notice... comprised of multiple sources, including physical (e.g., waves, earthquakes, ice, atmospheric...

  7. 76 FR 6406 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-04

    ... National Oceanic and Atmospheric Administration RIN 0648-XA116 Takes of Marine Mammals Incidental to... Fisheries Service (NMFS), National Oceanic and Atmospheric Administration (NOAA), Commerce. ACTION: Notice..., earthquakes, ice, and atmospheric noise. Biological noise includes sounds produced by marine mammals,...

  8. 78 FR 29705 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ... National Oceanic and Atmospheric Administration RIN 0648-XC646 Takes of Marine Mammals Incidental to... Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration (NOAA), Commerce. ACTION... comprised of multiple sources, including physical (e.g., waves, earthquakes, ice, atmospheric...

  9. Places for Children - Children's Places

    ERIC Educational Resources Information Center

    Rasmussen, Kim

    2004-01-01

    In their everyday lives, children largely stay within and relate to three settings - their homes, schools and recreational institutions. These environments have been created by adults and designated by them as "places for children". A more differentiated picture of children's spatial culture emerges when children discuss and take photographs of…

  10. 78 FR 19652 - Takes of Marine Mammals Incidental to Specified Activities; Office of Naval Research Acoustic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-02

    ...NMFS has received an application from the U.S. Navy's Office of Naval Research (ONR) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to conducting Acoustic Technology Experiments (ATE) in the western North Pacific Ocean. The Navy's activities are considered military readiness activities pursuant to the Marine Mammal Protection Act (MMPA), as......

  11. 75 FR 45527 - Taking and Importing Marine Mammals; Military Training Activities and Research, Development...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-03

    ... activity, which was published in the Federal Register on October 20, 2009 (74 FR 53796). This information... incidental take authorization. The description contained in the proposed rule has not changed (74 FR 53795... descriptions have not changed (74 FR 53795, pages 53797-53798). Description of Specified Activities...

  12. 75 FR 44770 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-29

    ... these activities and L-DEO has requested an authorization to take several marine mammals by Level B... the program in a previous notice for the proposed IHA (75 FR 28568, May 21, ] 2010). The activities to... source level of the array will increase in steps not exceeding six dB per five-minute period over a...

  13. Affordances for Risk-Taking and Physical Activity in Australian Early Childhood Education Settings

    ERIC Educational Resources Information Center

    Little, Helen; Sweller, Naomi

    2015-01-01

    Motor competence and physical activity (PA) patterns are established during the early childhood years. Early childhood education (ECE) settings are an important context for children's engagement in physically active play. This paper reports the findings from an online survey examining resources, spaces and affordances for PA and risk-taking in…

  14. 78 FR 7402 - Small Takes of Marine Mammals Incidental to Specified Activities; Cape Wind's High Resolution...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-01

    ...NMFS has received an application from Cape Wind Associates (CWA) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to pre-construction high resolution survey activities. CWA began pre-construction activities last year, but was unable to complete the entire survey. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments......

  15. Passive and active place avoidance as a tool of spatial memory research in rats.

    PubMed

    Cimadevilla, J M; Kaminsky, Y; Fenton, A; Bures, J

    2000-10-30

    A modified model of the arena described by Bures et al. (Bures J, Fenton AA, Kaminsky Y, Zinyuk L. Place cells and place navigation, Proc. Natl. Acad. Sci. USA. 1997a;94:343-350) was applied to the place learning of adult male rats in two different avoidance paradigms. In the passive avoidance task rats exploring a stationary circular arena had to avoid a 60 degrees sector entering of which was punished by mild footshocks. Intramaze as well as extramaze cues could be used for adequate solution of this task. In the active avoidance paradigm rats were trained to avoid a room frame defined sector (e.g. North-East) of a slowly rotating arena the movement of which forced the animals to rely on extramaze cues and to ignore intramaze information. Rats had to find an active solution of the task since otherwise they were passively transported into the room frame defined punished zone. The suitability of these tasks for testing spatial abilities of rats is discussed. PMID:11040412

  16. Putting Activism in Its Place: The Neighborhood Context of Participation in Neighborhood-Focused Activism

    PubMed Central

    Gilster, Megan E.

    2012-01-01

    Neighborhood-focused activism is one way residents enact their vision for their community. This study examines the neighborhood socioeconomic antecedents of participation in neighborhood-focused activism in a diverse sample of residents of Chicago neighborhoods to test three theories of neighborhood socioeconomic context and participation: 1) affluence affords participation, 2) activism addresses neighborhood needs associated with disadvantage, and 3) socioeconomic inequality creates contention that necessitates participation. Measuring neighborhood socioeconomic status as two unique dimensions, neighborhood affluence and neighborhood disadvantage, and accounting for both individual and neighborhood characteristics, I find support for each theory. Neighborhood socioeconomic context matters for participation, regardless of individual socioeconomic characteristics. Only when these three perspectives are considered jointly can they fully capture the socioeconomic context of participation in neighborhood-focused activism. PMID:24554811

  17. Putting Activism in Its Place: The Neighborhood Context of Participation in Neighborhood-Focused Activism.

    PubMed

    Gilster, Megan E

    2014-02-01

    Neighborhood-focused activism is one way residents enact their vision for their community. This study examines the neighborhood socioeconomic antecedents of participation in neighborhood-focused activism in a diverse sample of residents of Chicago neighborhoods to test three theories of neighborhood socioeconomic context and participation: 1) affluence affords participation, 2) activism addresses neighborhood needs associated with disadvantage, and 3) socioeconomic inequality creates contention that necessitates participation. Measuring neighborhood socioeconomic status as two unique dimensions, neighborhood affluence and neighborhood disadvantage, and accounting for both individual and neighborhood characteristics, I find support for each theory. Neighborhood socioeconomic context matters for participation, regardless of individual socioeconomic characteristics. Only when these three perspectives are considered jointly can they fully capture the socioeconomic context of participation in neighborhood-focused activism. PMID:24554811

  18. Understanding hippocampal activity by using purposeful behavior: Place navigation induces place cell discharge in both task-relevant and task-irrelevant spatial reference frames

    PubMed Central

    Zinyuk, L.; Kubik, S.; Kaminsky, Yu.; Fenton, A. A.; Bures, J.

    2000-01-01

    Continuous rotation of an arena in a cue-rich room dissociates the stationary room-bound information from the rotating arena-bound information. This disrupted spatial discharge in the majority of place cells from rats trained to collect randomly scattered food. In contrast, most place cell firing patterns recorded from rats trained to solve a navigation task on the rotating arena were preserved during the rotation. Spatial discharge was preserved in both the task-relevant stationary and the task-irrelevant rotating reference frames, but firing was more organized in the task-relevant frame. It is concluded that, (i) the effects of environmental manipulations can be understood with confidence only when the rat's purposeful behavior is used to formulate interpretations of the data, and (ii) hippocampal place cell activity is organized in multiple overlapping spatial reference frames. PMID:10716713

  19. 77 FR 32573 - Takes of Marine Mammals Incidental to Specified Activities; Construction and Race Event...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ...NMFS has received an application from the America's Cup Event Authority (ACEA) and the Port of San Francisco (Port) for an Incidental Harassment Authorization (IHA) to take marine mammals incidental to activities associated with the 34th America's Cup. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on its proposal to issue an IHA to ACEA and the Port to take,......

  20. Differential associations between impulsivity and risk-taking and brain activations underlying working memory in adolescents.

    PubMed

    Panwar, Karni; Rutherford, Helena J V; Mencl, W Einar; Lacadie, Cheryl M; Potenza, Marc N; Mayes, Linda C

    2014-11-01

    Increased impulsivity and risk-taking are common during adolescence and relate importantly to addictive behaviors. However, the extent to which impulsivity and risk-taking relate to brain activations that mediate cognitive processing is not well understood. Here we examined the relationships between impulsivity and risk-taking and the neural correlates of working memory. Neural activity was measured in 18 adolescents (13-18 years) while they engaged in a working memory task that included verbal and visuospatial components that each involved encoding, rehearsal and recognition stages. Risk-taking and impulsivity were assessed using the Balloon Analogue Risk Task (BART) and the adolescent version of the Barratt Impulsiveness Scale-11 (BIS-11A), respectively. We found overlapping as well as distinct regions subserving the different stages of verbal and visuospatial working memory. In terms of risk-taking, we found a positive correlation between BART scores and activity in subcortical regions (e.g., thalamus, dorsal striatum) recruited during verbal rehearsal, and an inverse correlation between BART scores and cortical regions (e.g., parietal and temporal regions) recruited during visuospatial rehearsal. The BIS-11A evidenced that motor impulsivity was associated with activity in regions recruited during all stages of working memory, while attention and non-planning impulsivity was only associated with activity in regions recruited during recognition. In considering working memory, impulsivity and risk-taking together, both impulsivity and risk-taking were associated with activity in regions recruited during rehearsal; however, during verbal rehearsal, differential correlations were found. Specifically, positive correlations were found between: (1) risk-taking and activity in subcortical regions, including the thalamus and dorsal striatum; and, (2) motor impulsivity and activity in the left inferior frontal gyrus, insula, and dorsolateral prefrontal cortex. Therefore

  1. 76 FR 54433 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ...In accordance with the Marine Mammal Protection Act (MMPA) regulations, notification is hereby given that NMFS has issued an Incidental Harassment Authorization (IHA) to the University of Alaska Geophysics Institute (UAGI) to take marine mammals, by harassment, incidental to conducting a marine geophysical seismic survey in the Arctic Ocean during September-October...

  2. 78 FR 56659 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-13

    ... National Oceanic and Atmospheric Administration RIN 0648-XC824 Takes of Marine Mammals Incidental to... Fisheries Service (NMFS), National Oceanic and Atmospheric Administration (NOAA), Commerce. ACTION: Notice..., earthquakes, ice, atmospheric sound), biological (e.g., sounds produced by marine mammals, fish,...

  3. 78 FR 52148 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-22

    ... National Oceanic and Atmospheric Administration RIN 0648-XC762 Takes of Marine Mammals Incidental to... Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration (NOAA), Commerce. ACTION... include physical (e.g., waves, earthquakes, ice, atmospheric sound), biological (e.g., sounds produced...

  4. The Influence of Prior Knowledge on the Retrieval-Directed Function of Note Taking in Prior Knowledge Activation

    ERIC Educational Resources Information Center

    Wetzels, Sandra A. J.; Kester, Liesbeth; van Merrienboer, Jeroen J. G.; Broers, Nick J.

    2011-01-01

    Background: Prior knowledge activation facilitates learning. Note taking during prior knowledge activation (i.e., note taking directed at retrieving information from memory) might facilitate the activation process by enabling learners to build an external representation of their prior knowledge. However, taking notes might be less effective in…

  5. 41 CFR 102-75.130 - If hazardous substance activity took place on the property, what specific information must an...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Utilization of Excess Real Property Title Report § 102-75.130 If hazardous substance activity took place on the property, what specific information must an agency include in the title report? If hazardous... activity took place on the property, what specific information must an agency include in the title...

  6. 41 CFR 102-75.130 - If hazardous substance activity took place on the property, what specific information must an...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Utilization of Excess Real Property Title Report § 102-75.130 If hazardous substance activity took place on the property, what specific information must an agency include in the title report? If hazardous... activity took place on the property, what specific information must an agency include in the title...

  7. 41 CFR 102-75.130 - If hazardous substance activity took place on the property, what specific information must an...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Utilization of Excess Real Property Title Report § 102-75.130 If hazardous substance activity took place on the property, what specific information must an agency include in the title report? If hazardous... activity took place on the property, what specific information must an agency include in the title...

  8. 41 CFR 102-75.130 - If hazardous substance activity took place on the property, what specific information must an...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Utilization of Excess Real Property Title Report § 102-75.130 If hazardous substance activity took place on the property, what specific information must an agency include in the title report? If hazardous... activity took place on the property, what specific information must an agency include in the title...

  9. 41 CFR 102-75.130 - If hazardous substance activity took place on the property, what specific information must an...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Utilization of Excess Real Property Title Report § 102-75.130 If hazardous substance activity took place on the property, what specific information must an agency include in the title report? If hazardous... activity took place on the property, what specific information must an agency include in the title...

  10. Monitoring Activity of Taking Medicine by Incorporating RFID and Video Analysis

    PubMed Central

    Hasanuzzaman, Faiz M.; Yang, Xiaodong; Tian, YingLi; Liu, Qingshan; Capezuti, Elizabeth

    2013-01-01

    In this paper, we present a new framework to monitor medication intake for elderly individuals by incorporating a video camera and Radio Frequency Identification (RFID) sensors. The proposed framework can provide a key function for monitoring activities of daily living (ADLs) of elderly people at their own home. In an assistive environment, RFID tags are applied on medicine bottles located in a medicine cabinet so that each medicine bottle will have a unique ID. The description of the medicine data for each tag is manually input to a database. RFID readers will detect if any of these bottles are taken away from the medicine cabinet and identify the tag attached on the medicine bottle. A video camera is installed to continue monitoring the activity of taking medicine by integrating face detection and tracking, mouth detection, background subtraction, and activity detection. The preliminary results demonstrate that 100% detection accuracy for identifying medicine bottles and promising results for monitoring activity of taking medicine. PMID:23914344

  11. 50 CFR 21.15 - Authorization of take incidental to military readiness activities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 8 2011-10-01 2011-10-01 false Authorization of take incidental to military readiness activities. 21.15 Section 21.15 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE..., EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS (CONTINUED) MIGRATORY BIRD PERMITS General...

  12. 76 FR 56735 - Small Takes of Marine Mammals Incidental to Specified Activities; Cape Wind's High Resolution...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-14

    ...NMFS has received a complete and adequate application from Cape Wind Associates for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to pre-construction high resolution survey activities. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is proposing to issue an IHA to Cape Wind Associates to incidentally harass, by Level B harassment, five......

  13. Performing Stenographic Activities. Take and Prepare Minutes of Meetings. Student's Manual and Instructor's Manual.

    ERIC Educational Resources Information Center

    Harrison, Pam

    Supporting performance objective 72 of the V-TECS (Vocational-Technical Education Consortium of States) Secretarial Catalog, both a set of student materials and an instructor's manual on taking and preparing minutes of meetings are included in this packet. (The packet is the third in a set of four on performing stenographic activities--CE 016…

  14. Performing Stenographic Activities. Take and Transcribe Shorthand Dictation. Student's Manual and Instructor's Manual.

    ERIC Educational Resources Information Center

    Harrison, Pam

    Supporting performance objective 73 of the V-TECS (Vocational-Technical Education Consortium of States) Secretarial Catalog, both a set of student materials and an instructor's manual on taking and transcribing shorthand dictation are included in this packet. (The packet is the second in a set of four on performing stenographic activities--CE 016…

  15. 78 FR 11844 - Taking of Marine Mammals Incidental to Specified Activities; Bremerton Ferry Terminal Wingwall...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-20

    ...NMFS has received a request from the Washington State Department of Transportation (WSDOT) Ferries Division (WSF) for an authorization to take small numbers of six species of marine mammals, by Level B harassment, incidental to proposed construction activities for the replacement of wingwalls at the Bremerton ferry terminal in Washington State. Pursuant to the Marine Mammal Protection Act......

  16. 78 FR 72643 - Taking of Marine Mammals Incidental to Specified Activities: Mukilteo Ferry Terminal Construction...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-03

    ...NMFS has received a request from the Washington State Department of Transportation (WSDOT) Ferries Division (WSF) for an authorization to take small numbers of eight species of marine mammals, by Level B harassment, incidental to proposed construction activities at the Mukilteo Multimodal Ferry Terminal in Mukilteo, Snohomish County, Washington. Pursuant to the Marine Mammal Protection Act......

  17. 77 FR 15722 - Takes of Marine Mammals Incidental to Specified Activities; Russian River Estuary Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-16

    ... involves pounding an impact hammer on the surface of the beach, creating a sound wave that resonates... issued an IHA, valid for a period of one year, on April 1, 2010 (75 FR 17382) and was subsequently issued a second IHA for incidental take associated with the same activities on April 21, 2011 (76 FR...

  18. 78 FR 14985 - Takes of Marine Mammals Incidental to Specified Activities; Russian River Estuary Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-08

    ... on the surface of the beach, creating a sound wave that resonates through the sand bar. It is not... first issued an IHA, valid for a period of one year, on April 1, 2010 (75 FR 17382), and was subsequently issued IHAs for incidental take associated with the same activities on April 21, 2011 (76 FR...

  19. 77 FR 24471 - Takes of Marine Mammals Incidental to Specified Activities; Russian River Estuary Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-24

    ... IHA, valid for a period of one year, on April 1, 2010 (75 FR 17382), and was subsequently issued a second IHA for incidental take associated with the same activities on April 21, 2011 (76 FR 23306... (Phoca vitulina), California sea lion (Zalophus californianus), and northern elephant seal...

  20. 76 FR 79157 - Takes of Marine Mammals Incidental to Specified Activities; St. George Reef Light Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-21

    ...NMFS has received an application from the St. George Reef Lighthouse Preservation Society (SGRLPS), for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment incidental to conducting aircraft operations, lighthouse renovation, and light maintenance activities on the St. George Reef Light Station on Northwest Seal Rock (NWSR) in the northeast Pacific Ocean from the......

  1. 50 CFR 18.27 - Regulations governing small takes of marine mammals incidental to specified activities.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... contained in the Act and in 50 CFR 18.3 and unless the context otherwise requires, in this section: Citizens.... (Complete definition of take is contained in 50 CFR 18.3.) Negligible impact is an impact resulting from the... marine mammals incidental to specified activities. 18.27 Section 18.27 Wildlife and Fisheries...

  2. 50 CFR 18.27 - Regulations governing small takes of marine mammals incidental to specified activities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... contained in the Act and in 50 CFR 18.3 and unless the context otherwise requires, in this section: Citizens.... (Complete definition of take is contained in 50 CFR 18.3.) Negligible impact is an impact resulting from the... marine mammals incidental to specified activities. 18.27 Section 18.27 Wildlife and Fisheries...

  3. 77 FR 73989 - Takes of Marine Mammals Incidental to Specified Activities; Seabird and Pinniped Research...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-12

    ...In accordance with the Marine Mammal Protection Act (MMPA) regulations, we hereby give notification that the National Marine Fisheries Service has issued an Incidental Harassment Authorization (IHA) to PRBO Conservation Science (PRBO), to take marine mammals, by Level B harassment, incidental to conducting seabird and pinniped research activities on Southeast Farallon Island, A[ntilde]o Nuevo......

  4. 78 FR 1838 - Takes of Marine Mammals Incidental to Specified Activities; St. George Reef Light Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-09

    ...We have received an application from the St. George Reef Lighthouse Preservation Society (Society), for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment incidental to conducting aircraft operations, lighthouse renovation, and light maintenance activities on the St. George Reef Light Station on Northwest Seal Rock (NWSR) in the northeast Pacific Ocean from the......

  5. 78 FR 66686 - Takes of Marine Mammals Incidental to Specified Activities; Seabird and Pinniped Research...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ...We, NMFS, have received an application from Point Blue Conservation Science (Point Blue, formerly PRBO Conservation Science), requesting an Incidental Harassment Authorization (Authorization) to take marine mammals, by harassment, incidental to conducting proposed seabird and pinniped research activities on Southeast Farallon Island, A[ntilde]o Nuevo Island, and Point Reyes National Seashore......

  6. Is It Possible for Teachers to Take Students beyond a Rudimentary Introduction to an Activity?

    ERIC Educational Resources Information Center

    Journal of Physical Education, Recreation & Dance, 2013

    2013-01-01

    This brief article presents student and professor responses to the question: Is it possible for teachers to take students beyond a rudimentary introduction to an activity? [Responses to this question were provided by Kevin Reilly, Terra Marjonen, Scott A. G. M. Crawford, Jason S. Whitworth, Brianne Mahoney, Erin Sereduk, Sam Thielen, Matt Lassen,…

  7. Mephedrone ('bath salt') elicits conditioned place preference and dopamine-sensitive motor activation.

    PubMed

    Lisek, Renata; Xu, Wei; Yuvasheva, Ekaterina; Chiu, Yi-Ting; Reitz, Allen B; Liu-Chen, Lee-Yuan; Rawls, Scott M

    2012-11-01

    Abuse of a dangerous street drug called mephedrone (4-methylmethcathinone) has become commonplace in the United States. Mephedrone is hypothesized to possess abuse liability, share pharmacological properties with psychostimulants, and display toxicity that has been linked to fatalities and non-fatal overdoses. Knowledge about the pharmacology of mephedrone has been obtained primarily from surveys of drug abusers and emergency room visits rather than experimental studies. The present study used motor activity and conditioned place preference (CPP) assays to investigate behavioral effects of mephedrone. Acute mephedrone (3, 5, 10, 30 mg/kg, ip) administration increased ambulatory activity in rats. Mephedrone (5 mg/kg, ip)-induced ambulation was inhibited by pretreatment with a dopamine D1 receptor antagonist (SCH 23390) (0.5, 1, 2 mg/kg, ip) and enhanced by pretreatment with a dopamine D2 receptor antagonist (sulpiride) (2 mg/kg, ip). Rats injected for 5 days with low dose mephedrone (0.5 mg/kg, ip) and then challenged with mephedrone (0.5 mg/kg, ip) following 10 days of abstinence displayed sensitization of ambulatory activity. In CPP experiments, mephedrone (30 mg/kg, ip) conditioning elicited a preference shift in both rats and mice. The CPP and dopamine-sensitive motor activation produced by mephedrone is suggestive of abuse liability and indicates commonalities between the neuropharmacological profiles of mephedrone and established drugs of abuse. PMID:22652295

  8. Active vibration reduction by optimally placed sensors and actuators with application to stiffened plates by beams

    NASA Astrophysics Data System (ADS)

    Daraji, A. H.; Hale, J. M.

    2014-10-01

    This study concerns new investigation of active vibration reduction of a stiffened plate bonded with discrete sensor/actuator pairs located optimally using genetic algorithms based on a developed finite element modeling. An isotropic plate element stiffened by a number of beam elements on its edges and having a piezoelectric sensor and actuator pair bonded to its surfaces is modeled using the finite element method and Hamilton’s principle, taking into account the effects of piezoelectric mass, stiffness and electromechanical coupling. The modeling is based on the first order shear deformation theory taking into account the effects of bending, membrane and shear deformation for the plate, the stiffening beam and the piezoelectric patches. A Matlab finite element program has been built for the stiffened plate model and verified with ANSYS and also experimentally. Optimal placement of ten piezoelectric sensor/actuator pairs and optimal feedback gain for active vibration reduction are investigated for a plate stiffened by two beams arranged in the form of a cross. The genetic algorithm was set up for optimization of sensor/actuator placement and feedback gain based on the minimization of the optimal linear quadratic index as an objective function to suppress the first six modes of vibration. Comparison study is presented for active vibration reduction of a square cantilever plate stiffened by crossed beams with two sensor/actuator configurations: firstly, ten piezoelectric sensor/actuator pairs are located in optimal positions; secondly, a piezoelectric layer of single sensor/actuator pair covering the whole of the stiffened plate as a SISO system.

  9. Altered Cingulate and Insular Cortex Activation During Risk-Taking in Methamphetamine Dependence: Losses Lose Impact

    PubMed Central

    Gowin, Joshua L.; Stewart, Jennifer L.; May, April C.; Ball, Tali M.; Wittmann, Marc; Tapert, Susan F.; Paulus, Martin P.

    2013-01-01

    Aims To determine if methamphetamine-dependent (MD) individuals exhibit behavioral or neural processing differences in risk-taking relative to healthy comparison participants (CTL). Design This was a cross-sectional study comparing two groups’ behavior on a risk-taking task and neural processing as assessed using functional magnetic resonance imaging (fMRI). Settings The study was conducted in an inpatient treatment center and a research fMRI facility in the United States. Participants Sixty-eight recently abstinent MD individuals recruited from a treatment program and forty CTL recruited from the community completed the study. Measurements The study assessed risk-taking behavior (overall and post-loss) using the Risky Gains Task (RGT), sensation-seeking, impulsivity and blood-oxygenation level dependent activation in the brain during the decision phase of the RGT. Findings Relative to CTL, MD displayed decreased activation in the bilateral rostral anterior cingulate cortex (ACC) and greater activation in the left insula across risky and safe decisions (p<.05). Right mid insula activation among CTL did not vary between risky and safe decisions, but among MD it was higher during risky relative to safe decisions (p<.05). Among MD, lower activation in the right rostral ACC (r=−.39, p<.01) and higher activation in the right mid insula (r=.35, p<.01) during risky decisions were linked to a higher likelihood of choosing a risky option following a loss. Conclusions Methamphetamine-dependent individuals show disrupted risk-related processing in both anterior cingulate and insula, brain areas that have been implicated in cognitive control and interoceptive processing. Attenuated neural processing of risky options may lead to risk-taking despite experiencing negative consequences. PMID:24033715

  10. 77 FR 42279 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-18

    ...In accordance with the regulations implementing the Marine Mammal Protection Act (MMPA) as amended, notification is hereby given that we have issued an incidental harassment authorization (IHA) to the U.S. Navy (Navy) to incidentally harass, by Level B harassment only, six species of marine mammals during construction activities associated with a wharf construction project in Hood Canal,......

  11. Dominance of the proximal coordinate frame in determining the locations of hippocampal place cell activity during navigation

    PubMed Central

    Siegel, Jennifer J.; Neunuebel, Joshua P.; Knierim, James J.

    2007-01-01

    The place-specific activity of hippocampal cells provides downstream structures with information regarding an animal's position within an environment, and perhaps the location of goals within that environment. In rodents, recent research has suggested that distal cues primarily set the orientation of the spatial representation, whereas the boundaries of the behavioral apparatus determine the locations of place activity. The current study was designed to address possible biases in some previous research that may have minimized the likelihood of observing place activity bound to distal cues. Hippocampal single-unit activity was recorded from 6 freely moving rats as they were trained to perform a tone-initiated place preference task on an open field platform. To investigate whether place activity was bound to the room- or platform-based coordinate frame (or both), the platform was translated within the room at an “early” and at a “late” phase of task acquisition (Shift 1 and Shift 2). At both time points, CA1 and CA3 place cells demonstrated room-associated and/or platform-associated activity, or remapped in response to the platform-shift. Shift 1 revealed place activity that reflected an interaction between a dominant platform-based (proximal) coordinate frame and a weaker room-based (distal) frame, as many CA1 and CA3 place fields shifted to a location intermediate to the two reference frames. Shift 2 resulted in place activity that became more strongly bound to either the platform- or room-based coordinate frame, suggesting the emergence of two independent spatial frames of reference (with many more cells participating in platform-based than room-based representations). PMID:17959742

  12. Solitary Waves in the Model of Active Media, Taking into Account Effects of Relaxation

    NASA Astrophysics Data System (ADS)

    Likus, W.; Vladimirov, V. A.

    2015-04-01

    We study a system of differential equations simulating transport phenomena in active structured media. The model is a generalization of McKean's modification of the celebrated FitzHugh-Nagumo system, describing the nerve impulse propagation in axon. It takes into account the effects of memory, connected with the presence of internal structure. We construct explicitly the localized traveling wave solutions and analyze their stability.

  13. Techniques: Paying Attention to the Place. Part 1--Activities for Instructors and Adult Learners [and] Part 2--Activities for Planning Places for Adult Learning.

    ERIC Educational Resources Information Center

    Fulton, Rodney D.

    1992-01-01

    This two-part article discusses the role of the physical environment in adult learning. In the first part, two activities--environment introduction and visualization--are discussed as ways to develop an awareness for improving the learning environment. In the second part, two planning activities--mapping and geometric coding--are discussed as ways…

  14. 76 FR 33721 - Takes of Marine Mammals Incidental to Specified Activities; Harbor Activities Related to the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-09

    ... 3, 2010 (74 FR 46742, September 11, 2009). The Delta IV/EELV launch vehicle is comprised of a common... activities). NMFS outlined the purpose of the program in the Notice of Proposed IHA (76 FR 21862, April 19, 2011). The activities to be conducted have not changed between the Notice of Proposed IHA (76 FR...

  15. Place and Being

    ERIC Educational Resources Information Center

    Cannatella, Howard

    2007-01-01

    Do places matter educationally? When Edward Casey remarks: "The world is, minimally and forever, a place-world", we might take this statement as presupposing without argument that places exist as a given, that we know what a place is, a point that Aristotle would have never taken for granted and in fact neither does Casey. I find Casey's remark…

  16. Validation of an Active Gear, Flexible Aircraft Take-off and Landing analysis (AGFATL)

    NASA Technical Reports Server (NTRS)

    Mcgehee, J. R.

    1984-01-01

    The results of an analytical investigation using a computer program for active gear, flexible aircraft take off and landing analysis (AGFATL) are compared with experimental data from shaker tests, drop tests, and simulated landing tests to validate the AGFATL computer program. Comparison of experimental and analytical responses for both passive and active gears indicates good agreement for shaker tests and drop tests. For the simulated landing tests, the passive and active gears were influenced by large strut binding friction forces. The inclusion of these undefined forces in the analytical simulations was difficult, and consequently only fair to good agreement was obtained. An assessment of the results from the investigation indicates that the AGFATL computer program is a valid tool for the study and initial design of series hydraulic active control landing gear systems.

  17. Effects of proton irradiation on a gas phase in which condensation takes place. I Negative Mg-26 anomalies and Al-26. [applied to solar and meteoritic composition

    NASA Technical Reports Server (NTRS)

    Heymann, D.; Dziczkaniec, M.; Walker, A.; Huss, G.; Morgan, J. A.

    1978-01-01

    In the present paper, isotopic effects in magnesium generated in a proton-irradiated gas phase are examined, taking only (p,n), (p,d), and (p, alpha) reactions in magnesium, aluminum, and silicon into consideration. In the presence of proton radiation, the three elements are 'removed' from the gas phase by condensation. It is required that a value of Al-26/Al-27 greater than 6 times 10 to the -5th must be reached, consistent with the value deduced by Lee Papanastassiou, and Wasserburg (1976) from their studies of the Allende meteorite. The calculations show that fast aluminum condensation reduces the required proton fluence substantially, that a significant fraction of aluminum remains uncondensed when the above value of the Al-26/Al-27 ratio is reached, that a detectable MG-24 excess is very likely to occur, that detectable negative MG-28 anomalies can be generated, and that proton fluxes and irradiation times can be varied simultaneously, and over a wide range of values, without significant changes in the required proton fluence.

  18. Leaf processing behaviour in Atta leafcutter ants: 90% of leaf cutting takes place inside the nest, and ants select pieces that require less cutting.

    PubMed

    Garrett, Ryan W; Carlson, Katherine A; Goggans, Matthew Scott; Nesson, Michael H; Shepard, Christopher A; Schofield, Robert M S

    2016-01-01

    Leafcutter ants cut trimmings from plants, carry them to their underground nests and cut them into smaller pieces before inoculating them with a fungus that serves as a primary food source for the colony. Cutting is energetically costly, so the amount of cutting is important in understanding foraging energetics. Estimates of the cutting density, metres of cutting per square metre of leaf, were made from samples of transported leaf cuttings and of fungal substrate from field colonies of Atta cephalotes and Atta colombica. To investigate cutting inside the nest, we made leaf-processing observations of our laboratory colony, A. cephalotes. We did not observe the commonly reported reduction of the leaf fragments into a pulp, which would greatly increase the energy cost of processing. Video clips of processing behaviours, including behaviours that have not previously been described, are linked. An estimated 2.9 (±0.3) km of cutting with mandibles was required to reduce a square metre of leaf to fungal substrate. Only about 12% (±1%) of this cutting took place outside of the nest. The cutting density and energy cost is lower for leaf material with higher ratios of perimeter to area, so we tested for, and found that the laboratory ants had a preference for leaves that were pre-cut into smaller pieces. Estimates suggest that the energy required to transport and cut up the leaf material is comparable to the metabolic energy available from the fungus grown on the leaves, and so conservation of energy is likely to be a particularly strong selective pressure for leafcutter ants. PMID:26909161

  19. Leaf processing behaviour in Atta leafcutter ants: 90% of leaf cutting takes place inside the nest, and ants select pieces that require less cutting

    PubMed Central

    Garrett, Ryan W.; Carlson, Katherine A.; Goggans, Matthew Scott; Nesson, Michael H.; Shepard, Christopher A.; Schofield, Robert M. S.

    2016-01-01

    Leafcutter ants cut trimmings from plants, carry them to their underground nests and cut them into smaller pieces before inoculating them with a fungus that serves as a primary food source for the colony. Cutting is energetically costly, so the amount of cutting is important in understanding foraging energetics. Estimates of the cutting density, metres of cutting per square metre of leaf, were made from samples of transported leaf cuttings and of fungal substrate from field colonies of Atta cephalotes and Atta colombica. To investigate cutting inside the nest, we made leaf-processing observations of our laboratory colony, A. cephalotes. We did not observe the commonly reported reduction of the leaf fragments into a pulp, which would greatly increase the energy cost of processing. Video clips of processing behaviours, including behaviours that have not previously been described, are linked. An estimated 2.9 (±0.3) km of cutting with mandibles was required to reduce a square metre of leaf to fungal substrate. Only about 12% (±1%) of this cutting took place outside of the nest. The cutting density and energy cost is lower for leaf material with higher ratios of perimeter to area, so we tested for, and found that the laboratory ants had a preference for leaves that were pre-cut into smaller pieces. Estimates suggest that the energy required to transport and cut up the leaf material is comparable to the metabolic energy available from the fungus grown on the leaves, and so conservation of energy is likely to be a particularly strong selective pressure for leafcutter ants. PMID:26909161

  20. Giving and taking: Representational building blocks of active resource-transfer events in human infants

    PubMed Central

    Tatone, Denis; Geraci, Alessandra; Csibra, Gergely

    2015-01-01

    Active resource transfer is a pervasive and distinctive feature of human sociality. We hypothesized that humans possess an action schema of giving specific for representing social interactions based on material exchange, and specified the set of necessary assumptions about giving events that this action schema should be equipped with. We tested this proposal by investigating how 12-month-old infants interpret abstract resource-transfer events. Across eight looking-time studies using a violation-of-expectation paradigm we found that infants were able to distinguish between kinematically identical giving and taking actions. Despite the surface similarity between these two actions, only giving was represented as an object-mediated social interaction. While we found no evidence that infants expected the target of a giving or taking action to reciprocate, the present results suggest that infants interpret giving as an inherently social action, which they can possibly use to map social relations via observing resource-transfer episodes. PMID:25614012

  1. Spatial Polygamy and Contextual Exposures (SPACEs): Promoting Activity Space Approaches in Research on Place and Health

    PubMed Central

    Matthews, Stephen A.; Yang, Tse-Chuan

    2014-01-01

    Exposure science has developed rapidly and there is an increasing call for greater precision in the measurement of individual exposures across space and time. Social science interest in an individual’s environmental exposure, broadly conceived, has arguably been quite limited conceptually and methodologically. Indeed, we appear to lag behind our exposure science colleagues in our theories, data, and methods. In this paper we discuss a framework based on the concept of spatial polygamy to demonstrate the need to collect new forms of data on human spatial behavior and contextual exposures across time and space. Adopting new data and methods will be essential if we want to better understand social inequality in terms of exposure to health risks and access to health resources. We discuss the opportunities and challenges focusing on the potential seemingly offered by focusing on human mobility, and specifically the utilization of activity space concepts and data. A goal of the paper is to spatialize social and health science concepts and research practice vis-a-vis the complexity of exposure. The paper concludes with some recommendations for future research focusing on theoretical and conceptual development, promoting research on new types of places and human movement, the dynamic nature of contexts, and on training. “When we elect wittingly or unwittingly, to work within a level … we tend to discern or construct – whichever emphasis you prefer – only those kinds of systems whose elements are confined to that level.”Otis Dudley Duncan (1961, p. 141). “…despite the new ranges created by improved transportation, local government units have tended to remain medieval in size.”Torsten Hägerstrand (1970, p.18) “A detective investigating a crime needs both tools and understanding. If he has no fingerprint powder, he will fail to find fingerprints on most surfaces. If he does not understand where the criminal is likely to have put his fingers, he will not

  2. Spatial Polygamy and Contextual Exposures (SPACEs): Promoting Activity Space Approaches in Research on Place and Health.

    PubMed

    Matthews, Stephen A; Yang, Tse-Chuan

    2013-08-01

    Exposure science has developed rapidly and there is an increasing call for greater precision in the measurement of individual exposures across space and time. Social science interest in an individual's environmental exposure, broadly conceived, has arguably been quite limited conceptually and methodologically. Indeed, we appear to lag behind our exposure science colleagues in our theories, data, and methods. In this paper we discuss a framework based on the concept of spatial polygamy to demonstrate the need to collect new forms of data on human spatial behavior and contextual exposures across time and space. Adopting new data and methods will be essential if we want to better understand social inequality in terms of exposure to health risks and access to health resources. We discuss the opportunities and challenges focusing on the potential seemingly offered by focusing on human mobility, and specifically the utilization of activity space concepts and data. A goal of the paper is to spatialize social and health science concepts and research practice vis-a-vis the complexity of exposure. The paper concludes with some recommendations for future research focusing on theoretical and conceptual development, promoting research on new types of places and human movement, the dynamic nature of contexts, and on training. "When we elect wittingly or unwittingly, to work within a level … we tend to discern or construct - whichever emphasis you prefer - only those kinds of systems whose elements are confined to that level."Otis Dudley Duncan (1961, p. 141)."…despite the new ranges created by improved transportation, local government units have tended to remain medieval in size."Torsten Hägerstrand (1970, p.18)"A detective investigating a crime needs both tools and understanding. If he has no fingerprint powder, he will fail to find fingerprints on most surfaces. If he does not understand where the criminal is likely to have put his fingers, he will not look in the right

  3. Taking up physical activity in later life and healthy ageing: the English longitudinal study of ageing

    PubMed Central

    Hamer, Mark; Lavoie, Kim L; Bacon, Simon L

    2014-01-01

    Background Physical activity is associated with improved overall health in those people who survive to older ages, otherwise conceptualised as healthy ageing. Previous studies have examined the effects of mid-life physical activity on healthy ageing, but not the effects of taking up activity later in life. We examined the association between physical activity and healthy ageing over 8 years of follow-up. Methods Participants were 3454 initially disease-free men and women (aged 63.7±8.9 years at baseline) from the English Longitudinal Study of Ageing, a prospective study of community dwelling older adults. Self-reported physical activity was assessed at baseline (2002–2003) and through follow-up. Healthy ageing, assessed at 8 years of follow-up (2010-2011), was defined as those participants who survived without developing major chronic disease, depressive symptoms, physical or cognitive impairment. Results At follow-up, 19.3% of the sample was defined as healthy ageing. In comparison with inactive participants, moderate (OR, 2.67, 95% CI 1.95 to 3.64), or vigorous activity (3.53, 2.54 to 4.89) at least once a week was associated with healthy ageing, after adjustment for age, sex, smoking, alcohol, marital status and wealth. Becoming active (multivariate adjusted, 3.37, 1.67 to 6.78) or remaining active (7.68, 4.18 to 14.09) was associated with healthy ageing in comparison with remaining inactive over follow-up. Conclusions Sustained physical activity in older age is associated with improved overall health. Significant health benefits were even seen among participants who became physically active relatively late in life. PMID:24276781

  4. Activated CD4+ T cells preferentially take up lipid microspheres, but resting cells do not.

    PubMed Central

    Suzuki, K

    1995-01-01

    Lipid microspheres (LM) used as drug carriers increase the effectiveness and reduce the toxicity of incorporated drugs. The present study is designed to determine whether or not activated T lymphocytes, which were the cells chosen first from the 'inflammatory cells', can take up LM in vitro. LM were labelled with a fluorescent probe, DiI (DiI-LM), to examine the kinetics. Flow cytometric analysis demonstrated that in freshly isolated peripheral blood mononuclear cells (PBMC), monocytes principally took up DiI-LM, while lymphocytes and granulocytes did not. When PBMC were stimulated with immobilized anti-CD3 MoAb and IL-2, cells expressing CD3, CD4, CD8 and CD16 incorporated DiI-LM. Purified CD4+ T cells, obtained by positive panning selection, were stimulated with this system. They were CD25, CD71, LFA-1-positive, and also showed an ability to take up DiI-LM, which resting cells did not. The findings were confirmed by flow cytometry and quantitative analysis of DiI. Confocal micrographs showed fluorescent granules from the probe in the cytoplasm of stimulated CD4+ T cells after incubation with DiI-LM. These results suggest that immunomodulatory agents incorporated into LM might selectively regulate the function of CD4+ or CD8+ T cells when these are activated. Images Fig. 4 PMID:7882572

  5. Hippocampal place cell and inhibitory neuron activity in disrupted-in-schizophrenia-1 mutant mice: implications for working memory deficits

    PubMed Central

    Mesbah-Oskui, Lia; Georgiou, John; Roder, John C

    2015-01-01

    Background: Despite the prevalence of working memory deficits in schizophrenia, the neuronal mechanisms mediating these deficits are not fully understood. Importantly, deficits in spatial working memory are identified in numerous mouse models that exhibit schizophrenia-like endophenotypes. The hippocampus is one of the major brain regions that actively encodes spatial location, possessing pyramidal neurons, commonly referred to as ‘place cells’, that fire in a location-specific manner. This study tests the hypothesis that mice with a schizophrenia-like endophenotype exhibit impaired encoding of spatial location in the hippocampus. Aims: To characterize hippocampal place cell activity in mice that exhibit a schizophrenia-like endophenotype. Methods: We recorded CA1 place cell activity in six control mice and six mice that carry a point mutation in the disrupted-in-schizophrenia-1 gene (Disc1-L100P) and have previously been shown to exhibit deficits in spatial working memory. Results: The spatial specificity and stability of Disc1-L100P place cells were similar to wild-type place cells. Importantly, however, Disc1-L100P place cells exhibited a higher propensity to increase their firing rate in a single, large location of the environment, rather than multiple smaller locations, indicating a generalization in their spatial selectivity. Alterations in the signaling and numbers of CA1 putative inhibitory interneurons and decreased hippocampal theta (5–12 Hz) power were also identified in the Disc1-L100P mice. Conclusions: The generalized spatial selectivity of Disc1-L100P place cells suggests a simplification of the ensemble place codes that encode individual locations and subserve spatial working memory. Moreover, these results suggest that deficient working memory in schizophrenia results from an impaired ability to uniquely code the individual components of a memory sequence. PMID:27336029

  6. Intracellular determinants of hippocampal CA1 place and silent cell activity in a novel environment.

    PubMed

    Epsztein, Jérôme; Brecht, Michael; Lee, Albert K

    2011-04-14

    For each environment a rodent has explored, its hippocampus contains a map consisting of a unique subset of neurons, called place cells, that have spatially tuned spiking there, with the remaining neurons being essentially silent. Using whole-cell recording in freely moving rats exploring a novel maze, we observed differences in intrinsic cellular properties and input-based subthreshold membrane potential levels underlying this division into place and silent cells. Compared to silent cells, place cells had lower spike thresholds and peaked versus flat subthreshold membrane potentials as a function of animal location. Both differences were evident from the beginning of exploration. Additionally, future place cells exhibited higher burst propensity before exploration. Thus, internal settings appear to predetermine which cells will represent the next novel environment encountered. Furthermore, place cells fired spatially tuned bursts with large, putatively calcium-mediated depolarizations that could trigger plasticity and stabilize the new map for long-term storage. Our results provide new insight into hippocampal memory formation. PMID:21482360

  7. An office‐place stepping device to promote workplace physical activity

    PubMed Central

    McAlpine, David A; Manohar, Chinmay U; McCrady, Shelly K; Hensrud, Donald; Levine, James A

    2007-01-01

    Objective It was proposed that an office‐place stepping device is associated with significant and substantial increases in energy expenditure compared to sitting energy expenditure. The objective was to assess the effect of using an office‐place stepping device on the energy expenditure of lean and obese office workers. Methods The office‐place stepping device is an inexpensive, near‐silent, low‐impact device that can be housed under a standard desk and plugged into an office PC for self‐monitoring. Energy expenditure was measured in lean and obese subjects using the stepping device and during rest, sitting and walking. 19 subjects (27±9 years, 85±23 kg): 9 lean (BMI<25 kg/m2) and 10 obese (BMI>29 kg/m2) attended the experimental office facility. Energy expenditure was measured at rest, while seated in an office chair, standing, walking on a treadmill and while using the office‐place stepping device. Results The office‐place stepping device was associated with an increase in energy expenditure above sitting in an office chair by 289±102 kcal/hour (p<0.001). The increase in energy expenditure was greater for obese (335±99 kcal/hour) than for lean subjects (235±80 kcal/hour; p = 0.03). The increments in energy expenditure were similar to exercise‐style walking. Conclusion The office‐place stepping device could be an approach for office workers to increase their energy expenditure. If the stepping device was used to replace sitting by 2 hours per day and if other components of energy balance were constant, weight loss of 20 kg/year could occur. PMID:17513333

  8. Impaired hippocampal activity at the goal zone on the place preference task in a DISC1 mouse model.

    PubMed

    Hayashi, Yuichiro; Sawa, Akira; Hikida, Takatoshi

    2016-05-01

    Learning deficit is a clinical feature of many mental disorders and is hypothesized to result from an inability to integrate information in neural systems. We showed that transgenic mice expressing a dominant-negative form of DISC1, a risk gene for neuropsychiatric disorders, exhibited impaired performance in a reward-place association task when combined with a mild isolation stress. CA1 cells in the mutant mice showed normal place cell properties, but their activity at the goal zone was diminished. This abnormality in hippocampal activity at the goal zone during the task may underlie the learning deficit observed in the DISC1 mutant mice. PMID:26497623

  9. When George Washington Takes Second Place.

    ERIC Educational Resources Information Center

    Ryan, Florence Holmes

    This document discusses biographies of women, chosen to appeal to young girls, including "So Young a Queen,""Indian Captive,""Wilderness Wife,""Louisa,""Molly Garfield in the White House,""I Mary,""I Varina,""Pattern for a Heroine: The Life Story of Rebecca Gratz,""Theodosia,""Child of the Silent Night,""The Silent Storm," and "Invincible Louisa."…

  10. The Body and the Place of Physical Activity in Education: Some Classical Perspectives

    ERIC Educational Resources Information Center

    Ozolinš, Janis

    2013-01-01

    The place of physical education has been contested in recent times and it has been argued that its justification as part of school curricula seems to be marginal at best. Such justifications as have been offered, propose that physical education is justified because of its contribution to moral development or because it is capable of being studied…

  11. The Greenhouse: A Place for Year-Round Plant Investigations.

    ERIC Educational Resources Information Center

    Hanif, Muhammad

    1989-01-01

    Activities that may take place in a greenhouse are discussed. Included are learning how to grow plants, plant growth, soil, vegetative reproduction, and plant habitat adaptations. Materials, procedures, and results are presented for the activities. (CW)

  12. Episodic-like memory trace in awake replay of hippocampal place cell activity sequences.

    PubMed

    Takahashi, Susumu

    2015-01-01

    Episodic memory retrieval of events at a specific place and time is effective for future planning. Sequential reactivation of the hippocampal place cells along familiar paths while the animal pauses is well suited to such a memory retrieval process. It is, however, unknown whether this awake replay represents events occurring along the path. Using a subtask switching protocol in which the animal experienced three subtasks as 'what' information in a maze, I here show that the replay represents a trial type, consisting of path and subtask, in terms of neuronal firing timings and rates. The actual trial type to be rewarded could only be reliably predicted from replays that occurred at the decision point. This trial-type representation implies that not only 'where and when' but also 'what' information is contained in the replay. This result supports the view that awake replay is an episodic-like memory retrieval process. PMID:26481131

  13. 77 FR 49277 - Takes of Marine Mammals During Specified Activities; Confined Blasting Operations by the U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... blasting activities and associated potential impacts. Drill holes are small in diameter (typically 2 to 4...) take small numbers of marine mammals, by Level B harassment, incidental to confined blasting operations... allow, upon request, the incidental, but not intentional, taking of small numbers of marine mammals of...

  14. 78 FR 60852 - Taking of Marine Mammals Incidental to Specified Activities; Construction of the East Span of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ...NMFS has received a request from the California Department of Transportation (CALTRANS) for an incidental take authorization to take small numbers of California sea lions, Pacific harbor seals, harbor porpoises, and gray whales, by harassment, incidental to construction activities associated with the East Span of the San Francisco-Oakland Bay Bridge (SF-OBB) in California. Pursuant to the......

  15. Encoding and Retrieving Faces and Places: Distinguishing Process- and Stimulus-Specific Differences in Brain Activity

    PubMed Central

    Prince, Steven E.; Dennis, Nancy A.; Cabeza, Roberto

    2009-01-01

    Among the most fundamental issues in cognitive neuroscience is how the brain may be organized into process-specific and stimulus-specific regions. In the episodic memory domain, most functional neuroimaging studies have focused on the former dimension, typically investigating the neural correlates of various memory processes. Thus, there is little information about what role stimulus-specific brain regions play in successful memory processes. To address this issue, the present event-related fMRI study used a factorial design to focus on the role of stimulus-specific brain regions, such as the fusiform face area (FFA) and parahippocampal place area (PPA) in successful encoding and retrieval processes. Searching within regions sensitive to faces or places, we identified areas similarly involved in encoding and retrieval, as well as areas differentially involved in encoding or retrieval. Finally, we isolated regions associated with successful memory, regardless of stimulus and process type. There were three main findings. Within face sensitive regions, anterior medial PFC and right FFA displayed equivalent encoding and retrieval success processes whereas left FFA was associated with successful encoding rather than retrieval. Within place sensitive regions, left PPA displayed equivalent encoding and retrieval success processes whereas right PPA was associated with successful encoding rather than retrieval. Finally, medial temporal and prefrontal regions were associated with general memory success, regardless of stimulus or process type. Taken together, our results clarify the contribution of different brain regions to stimulus- and process-specific episodic memory mechanisms. PMID:19524092

  16. 76 FR 28733 - Takes of Marine Mammals Incidental to Specified Activities; Pile-Driving and Renovation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... Harassment Authorization (IHA) to take small numbers of marine mammals, by Level B harassment, incidental to... is provided to the public for review. An authorization to take small numbers of marine mammals by... an authorization to incidentally take small numbers of marine mammals by harassment. Except...

  17. Hippocampal place cell and inhibitory neuron activity in Disrupted-in-schizophrenia-1 mutant mice: implications for working memory deficits

    PubMed Central

    Mesbah-Oskui, Lia; Georgiou, John; Roder, John C.

    2016-01-01

    Background Despite the prevalence of working memory deficits in schizophrenia, the neuronal mechanisms mediating these deficits are not fully understood1–3. Importantly, deficits in spatial working memory are identified in numerous mouse models that exhibit schizophrenia-like endophenotypes4–7. The hippocampus is one of the major brain regions that actively encodes spatial location, possessing pyramidal neurons, commonly referred to as ‘place cells’, that fire in a location-specific manner8. This study tests the hypothesis that mice with a schizophrenia-like endophenotype exhibit impaired encoding of spatial location in the hippocampus. Methods We recorded CA1 place cell activity in 6 control mice and 6 mice that carry a point mutation in the Disrupted-in-schizophrenia-1 gene (Disc1-L100P) and have previously been shown to exhibit deficits in spatial working memory4. Results The spatial specificity and stability of Disc1-L100P place cells were similar to wild-type place cells. Importantly, however, Disc1-L100P place cells exhibited a higher propensity to increase their firing rate in a single, large location of the environment, rather than multiple smaller locations, indicating a generalization in their spatial selectivity. Alterations in the signaling and numbers of CA1 putative inhibitory interneurons and decreased hippocampal theta (5–12Hz) power were also identified in the Disc1-L100P mice. Conclusions The generalized spatial selectivity of Disc1-L100P place cells suggests a simplification of the ensemble place codes that encode individual locations and subserve spatial working memory. Moreover, these results suggest that deficient working memory in schizophrenia results from an impaired ability to uniquely code the individual components of a memory sequence.

  18. Sensory feedback, error correction, and remapping in a multiple oscillator model of place-cell activity.

    PubMed

    Monaco, Joseph D; Knierim, James J; Zhang, Kechen

    2011-01-01

    Mammals navigate by integrating self-motion signals ("path integration") and occasionally fixing on familiar environmental landmarks. The rat hippocampus is a model system of spatial representation in which place cells are thought to integrate both sensory and spatial information from entorhinal cortex. The localized firing fields of hippocampal place cells and entorhinal grid-cells demonstrate a phase relationship with the local theta (6-10 Hz) rhythm that may be a temporal signature of path integration. However, encoding self-motion in the phase of theta oscillations requires high temporal precision and is susceptible to idiothetic noise, neuronal variability, and a changing environment. We present a model based on oscillatory interference theory, previously studied in the context of grid cells, in which transient temporal synchronization among a pool of path-integrating theta oscillators produces hippocampal-like place fields. We hypothesize that a spatiotemporally extended sensory interaction with external cues modulates feedback to the theta oscillators. We implement a form of this cue-driven feedback and show that it can retrieve fixed points in the phase code of position. A single cue can smoothly reset oscillator phases to correct for both systematic errors and continuous noise in path integration. Further, simulations in which local and global cues are rotated against each other reveal a phase-code mechanism in which conflicting cue arrangements can reproduce experimentally observed distributions of "partial remapping" responses. This abstract model demonstrates that phase-code feedback can provide stability to the temporal coding of position during navigation and may contribute to the context-dependence of hippocampal spatial representations. While the anatomical substrates of these processes have not been fully characterized, our findings suggest several signatures that can be evaluated in future experiments. PMID:21994494

  19. Episodic-like memory trace in awake replay of hippocampal place cell activity sequences

    PubMed Central

    Takahashi, Susumu

    2015-01-01

    Episodic memory retrieval of events at a specific place and time is effective for future planning. Sequential reactivation of the hippocampal place cells along familiar paths while the animal pauses is well suited to such a memory retrieval process. It is, however, unknown whether this awake replay represents events occurring along the path. Using a subtask switching protocol in which the animal experienced three subtasks as ‘what’ information in a maze, I here show that the replay represents a trial type, consisting of path and subtask, in terms of neuronal firing timings and rates. The actual trial type to be rewarded could only be reliably predicted from replays that occurred at the decision point. This trial-type representation implies that not only ‘where and when’ but also ‘what’ information is contained in the replay. This result supports the view that awake replay is an episodic-like memory retrieval process. DOI: http://dx.doi.org/10.7554/eLife.08105.001 PMID:26481131

  20. Connecting Activities: Making the Workplace a Learning Place. Education Research Brief

    ERIC Educational Resources Information Center

    Westrich, Keith; Leonard, Jennifer

    2008-01-01

    Connecting Activities was launched more than ten years ago to expose students to the world of work and help them see the relationship between what they are learning in school and their career aspirations. By linking education to worksite learning experiences, Connecting Activities provides a real-world context for teaching a more relevant…

  1. Older People and Social Connectedness: How Place and Activities Keep People Engaged

    PubMed Central

    Yen, Irene H.; Shim, Janet K.; Martinez, Airin D.; Barker, Judith C.

    2012-01-01

    To understand how older adults perceive and navigate their neighborhoods, we examined the implications of activity in their neighborhoods for their health. We interviewed 38 adults (ages 62–85) who lived in San Francisco or Oakland, California. Seven key themes emerged: (1) people express a wide range of expectations for neighborliness, from “we do not bother each other” to “we have keys to each other's houses”, (2) social distance between “other” people impede a sense of connection, (3) ethnic differences in living arrangements affect activities and activity locations, (4) people try to stay busy, (5) people able to leave their homes do many activities outside their immediate residential neighborhoods, (6) access to a car is a necessity for most, and (7) it is unusual to plan for the future when mobility might become limited. Multiple locations influence older adults' health, including residential neighborhoods. Older adults value mobility, active lives, and social connections. PMID:22272374

  2. “Fair Play”: A Videogame Designed to Address Implicit Race Bias Through Active Perspective Taking

    PubMed Central

    Kaatz, Anna; Chu, Sarah; Ramirez, Dennis; Samson-Samuel, Clem; Carnes, Molly

    2014-01-01

    Abstract Objective: Having diverse faculty in academic health centers will help diversify the healthcare workforce and reduce health disparities. Implicit race bias is one factor that contributes to the underrepresentation of Black faculty. We designed the videogame “Fair Play” in which players assume the role of a Black graduate student named Jamal Davis. As Jamal, players experience subtle race bias while completing “quests” to obtain a science degree. We hypothesized that participants randomly assigned to play the game would have greater empathy for Jamal and lower implicit race bias than participants randomized to read narrative text describing Jamal's experience. Materials and Methods: University of Wisconsin–Madison graduate students were recruited via e-mail and randomly assigned to play “Fair Play” or read narrative text through an online link. Upon completion, participants took an Implicit Association Test to measure implicit bias and answered survey questions assessing empathy toward Jamal and awareness of bias. Results: As hypothesized, gameplayers showed the least implicit bias but only when they also showed high empathy for Jamal (P=0.013). Gameplayers did not show greater empathy than text readers, and women in the text condition reported the greatest empathy for Jamal (P=0.008). However, high empathy only predicted lower levels of implicit bias among those who actively took Jamal's perspective through gameplay (P=0.014). Conclusions: A videogame in which players experience subtle race bias as a Black graduate student has the potential to reduce implicit bias, possibly because of a game's ability to foster empathy through active perspective taking. PMID:26192644

  3. Using MapMyFitness to Place Physical Activity into Neighborhood Context

    PubMed Central

    Hirsch, Jana A.; James, Peter; Robinson, Jamaica R. M.; Eastman, Kyler M.; Conley, Kevin D.; Evenson, Kelly R.; Laden, Francine

    2014-01-01

    It is difficult to obtain detailed information on the context of physical activity at large geographic scales, such as the entire United States, as well as over long periods of time, such as over years. MapMyFitness is a suite of interactive tools for individuals to track their workouts online or using global positioning system in their phones or other wireless trackers. This method article discusses the use of physical activity data tracked using MapMyFitness to examine patterns over space and time. An overview of MapMyFitness, including data tracked, user information, and geographic scope, is explored. We illustrate the utility of MapMyFitness data using tracked physical activity by users in Winston-Salem, NC, USA between 2006 and 2013. Types of physical activities tracked are described, as well as the percent of activities occurring in parks. Strengths of MapMyFitness data include objective data collection, low participant burden, extensive geographic scale, and longitudinal series. Limitations include generalizability, behavioral change as the result of technology use, and potential ethical considerations. MapMyFitness is a powerful tool to investigate patterns of physical activity across large geographic and temporal scales. PMID:24653982

  4. 77 FR 15045 - Takes of Marine Mammals Incidental to Specified Activities; Pile Placement for ORPC Maine's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-14

    ... FR 2701, January 19, 2012). Negligible Impact and Small Numbers Analysis and Determination NMFS has...), allowing the take of small numbers of marine mammals, by Level B harassment only, incidental to pile... request, the incidental, but not intentional, taking of small numbers of marine mammals by U.S....

  5. 75 FR 61426 - Takes of Marine Mammals Incidental to Specified Activities; Installation of Meteorological Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ... underwater noise levels. Since pile driving has the potential to take marine mammals, a marine mammal take... this action (75 FR 42698; July 22, 2010). Comments and Responses A notice of receipt and request for... (75 FR 42698). NMFS also made BOEM's EA available for comment during this time. During the...

  6. 50 CFR 18.27 - Regulations governing small takes of marine mammals incidental to specified activities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... contained in the Act and in 50 CFR 18.3 and unless the context otherwise requires, in this section: Citizens.... (Complete definition of take is contained in 50 CFR 18.3.) Negligible impact is an impact resulting from the... STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) TAKING,...

  7. 50 CFR 18.27 - Regulations governing small takes of marine mammals incidental to specified activities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... contained in the Act and in 50 CFR 18.3 and unless the context otherwise requires, in this section: Citizens.... (Complete definition of take is contained in 50 CFR 18.3.) Negligible impact is an impact resulting from the... STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) TAKING,...

  8. Social Science Theories on Adolescent Risk-Taking: The Relevance of Behavioral Inhibition and Activation

    ERIC Educational Resources Information Center

    Vermeersch, Hans; T'Sjoen, Guy; Kaufman, Jean-Marc; Van Houtte, Mieke

    2013-01-01

    The major social science theories on adolescent risk-taking--strain, social control, and differential association theories--have received substantial empirical support. The relationships between variables central to these theories and individual differences in temperament related to risk-taking, however, have not been adequately studied. In a…

  9. Activity recognition using a single accelerometer placed at the wrist or ankle

    PubMed Central

    Mannini, Andrea; Intille, Stephen S.; Rosenberger, Mary; Sabatini, Angelo M.; Haskell, William

    2013-01-01

    PURPOSE Large physical activity surveillance projects such as the UK Biobank and NHANES are using wrist-worn accelerometer-based activity monitors that collect raw data. The goal is to increase wear time by asking subjects to wear the monitors on the wrist instead of the hip, and then to use information in the raw signal to improve activity type and intensity estimation. The purpose of this work is obtaining an algorithm to process wrist and ankle raw data and classify behavior into four broad activity classes: ambulation, cycling, sedentary and other. METHODS Participants (N = 33) wearing accelerometers on the wrist and ankle performed 26 daily activities. The accelerometer data were collected, cleaned, and preprocessed to extract features that characterize 2 s, 4 s, and 12.8 s data windows. Feature vectors encoding information about frequency and intensity of motion extracted from analysis of the raw signal were used with a support vector machine classifier to identify a subject’s activity. Results were compared with categories classified by a human observer. Algorithms were validated using a leave-one-subject-out strategy. The computational complexity of each processing step was also evaluated. RESULTS With 12.8 s windows, the proposed strategy showed high classification accuracies for ankle data (95.0%) that decreased to 84.7% for wrist data. Shorter (4 s) windows only minimally decreased performances of the algorithm on the wrist to 84.2%. CONCLUSIONS A classification algorithm using 13 features shows good classification into the four classes given the complexity of the activities in the original dataset. The algorithm is computationally-efficient and could be implemented in real-time on mobile devices with only 4 s latency. PMID:23604069

  10. Place Disparities in Supportive Environments for Extracurricular Physical Activity in North Carolina Middle Schools

    ERIC Educational Resources Information Center

    Edwards, Michael B.; Bocarro, Jason N.; Kanters, Michael A.

    2013-01-01

    Disadvantaged rural youth may be especially at risk for obesity and poorer health due to physical inactivity. Research suggests that extracurricular school programs can increase physical activity for this population. This study sought to determine whether local differences existed in the availability of supportive environments for extracurricular…

  11. Using an Informal Cardiovascular System Activity to Study the Effectiveness of Science Education in Unexpected Places

    ERIC Educational Resources Information Center

    Monzack, Elyssa Lynne; Zenner Petersen, Greta M.

    2011-01-01

    Venues for informal science education are usually those sought out by people who are specifically looking for an educational experience. Whether planning a trip to a museum or choosing a television program, these individuals are actively seeking an informal educational experience; they are a self-selected group. This paper investigates whether…

  12. Does Father Absence Place Daughters at Special Risk for Early Sexual Activity and Teenage Pregnancy?

    ERIC Educational Resources Information Center

    Ellis, Bruce J.; Bates, John E.; Dodge, Kenneth A.; Fergusson, David M.; Horwood, L. John; Pettit, Gregory S.; Woodward, Lianne

    2003-01-01

    Longitudinal studies in two countries investigated impact of father absence on girls' early sexual activity (ESA) and teenage pregnancy. Findings indicated that greater exposure to father absence strongly related to elevated ESA and adolescent pregnancy risk. Elevated risk was not explained (U.S. sample) or only partly explained (New Zealand…

  13. Public Libraries as Places for Empowering Women through Autonomous Learning Activities

    ERIC Educational Resources Information Center

    Yoshida, Yuko

    2013-01-01

    Introduction. The purpose of this research is to investigate the significance of public libraries as educational institutions. The meaning of lifelong learning in public libraries from the perspective of women's autonomous activities is re-examined. Method. The literature of the grassroots library movement and that of the empowerment of women…

  14. 77 FR 6080 - Taking and Importing Marine Mammals; U.S. Navy's Atlantic Fleet Active Sonar Training

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ...In accordance with the Marine Mammal Protection Act (MMPA), as amended, and implementing regulations, notice is hereby given that NMFS has issued a letter of authorization (LOA) to the U.S. Navy (Navy) to take marine mammals incidental to Navy training, maintenance, and research, development, testing, and evaluation (RDT&E) activities to be conducted within the Atlantic Fleet Active Sonar......

  15. Double Take

    ERIC Educational Resources Information Center

    Educational Leadership, 2011

    2011-01-01

    This paper begins by discussing the results of two studies recently conducted in Australia. According to the two studies, taking a gap year between high school and college may help students complete a degree once they return to school. The gap year can involve such activities as travel, service learning, or work. Then, the paper presents links to…

  16. Elbow and wrist joint contact forces during occupational pick and place activities.

    PubMed

    Chadwick, E K; Nicol, A C

    2000-05-01

    A three-dimensional, mathematical model of the elbow and wrist joints, including 15 muscle units, 3 ligaments and 4 joint forces, has been developed. A new strain gauge transducer has been developed to measure functional grip forces. The device measures radial forces divided into six components and forces of up to 250N per segment can be measured with an accuracy of +/-1%. Ten normal volunteers were asked to complete four tasks representing occupational activities, during which time their grip force was monitored. Together with kinematic information from the six-camera Vicon data, the moment effect of these loads at the joints was calculated. These external moments are assumed to be balanced by the internal moments, generated by the muscles, passive soft tissue and bone contact. The effectiveness of the body's internal structures in generating joint moments was assessed by studying the geometry of a simplified model of the structures, where information about the lines of action and moment arms of muscles, tendons and ligaments is contained. The assumption of equilibrium between these external and internal joint moments allows formulation of a set of equations from which muscle and joint forces can be calculated. A two stage, linear optimisation routine minimising the overall muscle stress and the sum of the joint forces has been used to overcome the force-sharing problem. Humero-ulnar forces of up to 1600N, humero-radial forces of up to 800N and wrist joint forces of up to 2800N were found for moderate level activity. The model was validated by comparison with other studies. PMID:10708780

  17. 75 FR 80471 - Takes of Marine Mammals Incidental to Specified Activities; St. George Reef Light Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-22

    ... National Oceanic and Atmospheric Administration RIN 0648-XZ87 Takes of Marine Mammals Incidental to... Norte County, CA AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric... frequently used in the discussions of acoustic effects in this document. Sound pressure is the sound...

  18. 75 FR 17382 - Small Takes of Marine Mammals Incidental to Specified Activities; Russian River Estuary Water...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-06

    ... Federal Register (74 FR 58248) for the take of marine mammals incidental to Estuary water level management... notice (74 FR 58248). In summary, harbor seals are the most abundant marine mammal found at the mouth of... published on November 12, 2009 (74 FR 58248). During the 30-day public comment period, six members of...

  19. 75 FR 39335 - Incidental Takes of Marine Mammals During Specified Activities; Marine Seismic Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-08

    ...NMFS has received an application from the U.S. Geological Survey (USGS) for an Incidental Harassment Authorization (IHA) to take small numbers of marine mammals, by harassment, incidental to conducting a marine seismic survey in the Arctic Ocean during August to September, 2010. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS requests comments on its proposal to authorize USGS to......

  20. 77 FR 47603 - Takes of Marine Mammals Incidental to Specified Activities; Construction and Race Event...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-09

    ... Federal Register notice of proposed authorization (hereafter, the FR notice; 77 FR 32573; June 1, 2012... greater detail in the FR notice. Temporary floating docks will be installed utilizing 18-in steel pipe... provided in the FR notice. Because we do not plan to authorize take of marine mammals incidental to...

  1. 76 FR 47155 - Takes of Marine Mammals Incidental to Specified Activities; Pile-Driving and Renovation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-04

    ...In accordance with the Marine Mammal Protection Act (MMPA) regulation, notification is hereby given that NMFS has issued an Incidental Harassment Authorization (IHA) to the Cher-Ae Heights Indian Community of the Trinidad Rancheria (Trinidad Rancheria) to take small numbers of marine mammals, by Level B harassment, incidental to pile- driving and renovation operations for the Trinidad Pier......

  2. 77 FR 58255 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey off the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-19

    ...NMFS has received an application from the Lamont-Doherty Earth Observatory of Columbia University (L-DEO), in cooperation with the Pacific Gas and Electric Company (PG&E), for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to conducting a marine geophysical (seismic) survey off the central coast of California, November to December, 2012. Pursuant......

  3. 76 FR 71940 - Takes of Marine Mammals Incidental to Specified Activities; Physical Oceanographic Studies in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-21

    ...NMFS has received an application from the United States Navy (Navy) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to conducting physical oceanographic studies in the southwest Indian Ocean, January through February, 2012. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on its proposal to issue an IHA to the......

  4. 77 FR 4765 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-31

    ...NMFS has received an application from Lamont-Doherty Earth Observatory (L-DEO), a part of Columbia University, for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to conducting a marine geophysical survey in the northwest Pacific Ocean, March through April,...

  5. 78 FR 17359 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-21

    ...NMFS has received an application from the Lamont-Doherty Earth Observatory of Columbia University (L-DEO) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to conducting a marine geophysical (seismic) survey in the northeast Atlantic Ocean, June to July, 2013. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on......

  6. 75 FR 66065 - Small Takes of Marine Mammals Incidental to Specified Activities; Exploratorium Relocation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-27

    ... (75 FR 42691), requesting comments from the public on the proposed IHA. Description of the Specified... Federal Register (75 FR 42691, July 22, 2010) and a summary is provided here. To make room for the new... Authorization (IHA) to the Exploratorium, allowing the take of small numbers of marine mammals, by Level...

  7. 75 FR 11121 - Incidental Takes of Marine Mammals During Specified Activities; Replacement and Repair of Fur...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... FR 17888) because it declined to less than 50 percent of levels observed in the late 1950s and no... been divided by the percentage estimated on land for each week in Tables 3a to 3e (below). NMFS summed the daily take estimates into weekly bins (Table 3a to 3e) because few animals were predicted on...

  8. 75 FR 64996 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-21

    ...In accordance with the Marine Mammal Protection Act (MMPA) regulations, notification is hereby given that NMFS has issued an Incidental Harassment Authorization (IHA) to Scripps Institution of Oceanography (SIO), a part of the University of California, to take small numbers of marine mammals, by harassment, incidental to conducting a marine geophysical survey in the eastern tropical Pacific......

  9. 50 CFR 18.27 - Regulations governing small takes of marine mammals incidental to specified activities.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Collection Clearance Officer at the address provided at 50 CFR 2.1(b). (c) Definitions. In addition to definitions contained in the Act and in 50 CFR 18.3 and unless the context otherwise requires, in this section.... (Complete definition of take is contained in 50 CFR 18.3.) Negligible impact is an impact resulting from...

  10. 76 FR 26255 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-06

    ... species for which no takes are being requested (i.e., North Pacific right, sei, blue, and beluga whales) are sighted at any distance from the vessel. Ramp-up will only begin if the whale has not been seen...., unidentified dolphin, sperm whale), types and nature of sounds heard (e.g., clicks, continuous,...

  11. 77 FR 43259 - Takes of Marine Mammals Incidental to Specified Activities; Pile Driving for Honolulu Seawater...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-24

    ...NMFS has received a complete and adequate application from Honolulu Seawater Air Conditioning, LLC (HSWAC) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to pile driving offshore Honolulu, Hawaii. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is proposing to issue an IHA to incidentally harass, by Level B harassment, 17 species of......

  12. 76 FR 49737 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-11

    ...In accordance with the Marine Mammal Protection Act (MMPA) regulation, notification is hereby given that NMFS has issued an Incidental Harassment Authorization (IHA) to the U.S. Geological Survey (USGS) to take marine mammals, by Level B harassment, incidental to conducting a marine geophysical survey in the central-western Bering Sea, August...

  13. 76 FR 20325 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-12

    ...In accordance with the Marine Mammal Protection Act (MMPA) regulations, notification is hereby given that NMFS has issued an Incidental Harassment Authorization (IHA) to Lamont-Doherty Earth Observatory (L-DEO), a part of Columbia University, to take small numbers of marine mammals, by Level B harassment, incidental to conducting a marine geophysical survey in the eastern tropical Pacific......

  14. Students Taking Charge: Inside the Learner-Active, Technology-Infused Classroom

    ERIC Educational Resources Information Center

    Sulla, Nancy

    2011-01-01

    Teachers and administrators who recognize the needs of today's society and students, and their impact on teaching and learning, can use this book to create student-centered classrooms that make technology a vital part of their lessons. Filled with practical examples and step-by-step guidelines, "Students Taking Charge" will help educators design…

  15. 77 FR 8811 - Takes of Marine Mammals Incidental to Specified Activities; St. George Reef Light Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-15

    ...In accordance with the regulations implementing the Marine Mammal Protection Act (MMPA) as amended, notification is hereby given that NMFS has issued an Incidental Harassment Authorization (IHA) to the St. George Reef Lighthouse Preservation Society (SGRLPS) to take marine mammals, by Level B harassment only, incidental to conducting aircraft operations, and lighthouse renovation and light......

  16. 78 FR 71576 - Takes of Marine Mammals Incidental to Specified Activities; St. George Reef Light Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ...In accordance with the regulations implementing the Marine Mammal Protection Act (MMPA) as amended, notification is hereby given that we, NMFS, have issued an Incidental Harassment Authorization (Authorization) to the St. George Reef Lighthouse Preservation Society (Society) to take four species of marine mammals, by Level B harassment only, incidental to conducting helicopter operations, and......

  17. 77 FR 52755 - Programmatic Incidental Take Permit and Environmental Assessment for Development Activities...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-30

    ... conducted or permitted by the Applicant: The endangered Perdido Key beach mouse (Peromyscus polionotus... barrier island 16.9 miles long, constitutes the entire historic range of the Perdido Key beach mouse. The... requirements are met, we will issue the ITP for the incidental take of Perdido Key beach mouse,...

  18. 76 FR 18167 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ...NMFS has received an application from the U.S. Geological Survey (USGS) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to conducting a marine geophysical survey in the central Gulf of Alaska (GOA), June, 2011. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on its proposal to issue an IHA to USGS to......

  19. 77 FR 25966 - Takes of Marine Mammals Incidental to Specified Activities; Three Marine Geophysical Surveys in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-02

    ...We have received an application from the Lamont-Doherty Earth Observatory, a part of Columbia University, for an Incidental Harassment Authorization to take marine mammals, by harassment, incidental to conducting three consecutive marine geophysical surveys in the northeast Pacific Ocean, June through July...

  20. 78 FR 40705 - Takes of Marine Mammals Incidental to Specified Activities; Demolition and Construction...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-08

    .... Observe them from a safe distance and keep pets on a leash. Marine mammals are wild animals and can be... National Oceanic and Atmospheric Administration RIN 0648-XC498 Takes of Marine Mammals Incidental to... Jolla, California AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and...

  1. The Use of Parent Involved Take-Home Science Activities during Student Teaching: Understanding the Challenges of Implementation

    ERIC Educational Resources Information Center

    Zarazinski, Jill

    2010-01-01

    The purpose of this study was to identify student teachers use and implementation of "Science in a Bag" when it was no longer a required course-based assessment. This take-home science activity acted as the elaboration component of the 5Es lesson teacher candidates designed and taught in the classroom, utilized household items, and directly…

  2. "Take Care of Yourself" [Program for Older Adults. Dance Movement Activities' Implications for Use as Therapeutic Interventions].

    ERIC Educational Resources Information Center

    Snodgrass, Jeanne

    A description is given of the "Take Care of Yourself" program which is an interdiscplinary program designed to provide health education and dance/exercise for older adults as well as gerontology field experience for medical and dance/exercise science students. The program offers older adults an opportunity to maintain and regain an active, more…

  3. 78 FR 42042 - Taking of Marine Mammals Incidental to Specified Activities; U.S. Marine Corps Training Exercises...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-15

    ... FR 19224, Friday, March 29, 2013) and taking into account that only 36 percent of the ordnance... Corps for the conduct of the same activities from 2010 to 2012 (75 FR 72807, November 26, 2010; 77 FR... the purpose of the program in a previous notice for the proposed Authorization (78 FR 19224,...

  4. 77 FR 87 - Taking of Marine Mammals Incidental to Specified Activities; U.S. Marine Corps Training Exercises...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-03

    ...In accordance with the Marine Mammal Protection Act (MMPA) regulations, notification is hereby given that NMFS has issued an Incidental Harassment Authorization (IHA) to the U.S. Marine Corps (USMC) to take marine mammals, by Level B harassment only, incidental to military training exercises at Marine Corps Air Station (MCAS) Cherry Point Range Complex, North Carolina. The USMC's activities......

  5. Exercise Level and Energy Expenditure in the Take 10![R] In-Class Physical Activity Program.

    ERIC Educational Resources Information Center

    Stewart, James A.; Dennison, David A.; Kohl, Harold W., III; Doyle, J. Andrew

    2004-01-01

    This study evaluated the effectiveness of an innovative, classroom-based physical activity prevention program designed to integrate academic curriculum elements along with a physical activity program in providing moderate-to-vigorous intensity physical activity. A convenience sample of three public school classrooms (one first, third, and fifth…

  6. Acute ischemic stroke treated with intravenous tissue plasminogen activator in a patient taking dabigatran with radiographic evidence of recanalization.

    PubMed

    Sangha, Navdeep; El Khoury, Ramy; Misra, Vivek; Lopez, George

    2012-11-01

    Dabigatran etexelate is a new oral direct thrombin inhibitor that has been approved by the US Food and Drug Administration to prevent stroke in patients with nonvalvular atrial fibrillation. A 51-year-old man with a history of atrial fibrillation who was taking dabigatran presented with an acute ischemic stroke. The patient had a normal international normalized ratio, activated partial thromboplastin time, and an elevated thrombin time of 26.4 seconds. Recanalization of the middle cerebral artery with intravenous tissue plasminogen activator was apparent on digital subtraction angiography, and there was no evidence of intracerebral hemorrhage on the repeat computed tomographic scan. This is the first report of a patient who was taking dabigatran etexilate and who had an ischemic stroke caused by a middle cerebral artery occlusion, with an elevated thrombin time and radiographic recanalization with intravenous tissue plasminogen activator without evidence of hemorrhagic transformation. PMID:22683118

  7. Supramammillary serotonin reduction alters place learning and concomitant hippocampal, septal, and supramammillar theta activity in a Morris water maze.

    PubMed

    Hernández-Pérez, J Jesús; Gutiérrez-Guzmán, Blanca E; López-Vázquez, Miguel Á; Olvera-Cortés, María E

    2015-01-01

    Hippocampal theta activity is related to spatial information processing, and high-frequency theta activity, in particular, has been linked to efficient spatial memory performance. Theta activity is regulated by the synchronizing ascending system (SAS), which includes mesencephalic and diencephalic relays. The supramamillary nucleus (SUMn) is located between the reticularis pontis oralis and the medial septum (MS), in close relation with the posterior hypothalamic nucleus (PHn), all of which are part of this ascending system. It has been proposed that the SUMn plays a role in the modulation of hippocampal theta-frequency; this could occur through direct connections between the SUMn and the hippocampus or through the influence of the SUMn on the MS. Serotonergic raphe neurons prominently innervate the hippocampus and several components of the SAS, including the SUMn. Serotonin desynchronizes hippocampal theta activity, and it has been proposed that serotonin may regulate learning through the modulation of hippocampal synchrony. In agreement with this hypothesis, serotonin depletion in the SUMn/PHn results in deficient spatial learning and alterations in CA1 theta activity-related learning in a Morris water maze. Because it has been reported that SUMn inactivation with lidocaine impairs the consolidation of reference memory, we asked whether changes in hippocampal theta activity related to learning would occur through serotonin depletion in the SUMn, together with deficiencies in memory. We infused 5,7-DHT bilaterally into the SUMn in rats and evaluated place learning in the standard Morris water maze task. Hippocampal (CA1 and dentate gyrus), septal and SUMn EEG were recorded during training of the test. The EEG power in each region and the coherence between the different regions were evaluated. Serotonin depletion in the SUMn induced deficient spatial learning and altered the expression of hippocampal high-frequency theta activity. These results provide evidence in

  8. Supramammillary serotonin reduction alters place learning and concomitant hippocampal, septal, and supramammillar theta activity in a Morris water maze

    PubMed Central

    Hernández-Pérez, J. Jesús; Gutiérrez-Guzmán, Blanca E.; López-Vázquez, Miguel Á.; Olvera-Cortés, María E.

    2015-01-01

    Hippocampal theta activity is related to spatial information processing, and high-frequency theta activity, in particular, has been linked to efficient spatial memory performance. Theta activity is regulated by the synchronizing ascending system (SAS), which includes mesencephalic and diencephalic relays. The supramamillary nucleus (SUMn) is located between the reticularis pontis oralis and the medial septum (MS), in close relation with the posterior hypothalamic nucleus (PHn), all of which are part of this ascending system. It has been proposed that the SUMn plays a role in the modulation of hippocampal theta-frequency; this could occur through direct connections between the SUMn and the hippocampus or through the influence of the SUMn on the MS. Serotonergic raphe neurons prominently innervate the hippocampus and several components of the SAS, including the SUMn. Serotonin desynchronizes hippocampal theta activity, and it has been proposed that serotonin may regulate learning through the modulation of hippocampal synchrony. In agreement with this hypothesis, serotonin depletion in the SUMn/PHn results in deficient spatial learning and alterations in CA1 theta activity-related learning in a Morris water maze. Because it has been reported that SUMn inactivation with lidocaine impairs the consolidation of reference memory, we asked whether changes in hippocampal theta activity related to learning would occur through serotonin depletion in the SUMn, together with deficiencies in memory. We infused 5,7-DHT bilaterally into the SUMn in rats and evaluated place learning in the standard Morris water maze task. Hippocampal (CA1 and dentate gyrus), septal and SUMn EEG were recorded during training of the test. The EEG power in each region and the coherence between the different regions were evaluated. Serotonin depletion in the SUMn induced deficient spatial learning and altered the expression of hippocampal high-frequency theta activity. These results provide evidence in

  9. Taking a New Look at the Physical Activity Program on the College and University Level.

    ERIC Educational Resources Information Center

    LaPoint, James D., Ed.; And Others

    1982-01-01

    Physical activity programs at the college level should aim toward: (1) maintenance of physical fitness; (2) refinement of skills; (3) introduction to new skills; and (4) development of healthy lifestyles. Innovative activity courses such as aerobic dance, weight lifting, and adventure programs are also being offered to reach these goals. (JN)

  10. 76 FR 30311 - Takes of Marine Mammals Incidental to Specified Activities; Seabird and Pinniped Research...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... research activities on Southeast Farallon Island, A o Nuevo Island, and Point Reyes National Seashore in... activities on Southeast Farallon Island, A o Nuevo Island, and Point Reyes National Seashore in central California (CA). PRBO, along with partners Oikonos Ecosystem Knowledge ] and Point Reyes National...

  11. Taking It to the Classroom: Number Board Games as a Small Group Learning Activity

    ERIC Educational Resources Information Center

    Ramani, Geetha B.; Siegler, Robert S.; Hitti, Aline

    2012-01-01

    We examined whether a theoretically based number board game could be translated into a practical classroom activity that improves Head Start children's numerical knowledge. Playing the number board game as a small group learning activity promoted low-income children's number line estimation, magnitude comparison, numeral identification, and…

  12. Changes in visual perspective influence brain activity patterns during cognitive perspective-taking of other people's pain.

    PubMed

    Vistoli, Damien; Achim, Amélie M; Lavoie, Marie-Audrey; Jackson, Philip L

    2016-05-01

    Empathy refers to our capacity to share and understand the emotional states of others. It relies on two main processes according to existing models: an effortless affective sharing process based on neural resonance and a more effortful cognitive perspective-taking process enabling the ability to imagine and understand how others feel in specific situations. Until now, studies have focused on factors influencing the affective sharing process but little is known about those influencing the cognitive perspective-taking process and the related brain activations during vicarious pain. In the present fMRI study, we used the well-known physical pain observation task to examine whether the visual perspective can influence, in a bottom-up way, the brain regions involved in taking others' cognitive perspective to attribute their level of pain. We used a pseudo-dynamic version of this classic task which features hands in painful or neutral daily life situations while orthogonally manipulating: (1) the visual perspective with which hands were presented (first-person versus third-person conditions) and (2) the explicit instructions to imagine oneself or an unknown person in those situations (Self versus Other conditions). The cognitive perspective-taking process was investigated by comparing Other and Self conditions. When examined across both visual perspectives, this comparison showed no supra-threshold activation. Instead, the Other versus Self comparison led to a specific recruitment of the bilateral temporo-parietal junction when hands were presented according to a first-person (but not third-person) visual perspective. The present findings identify the visual perspective as a factor that modulates the neural activations related to cognitive perspective-taking during vicarious pain and show that this complex cognitive process can be influenced by perceptual stages of information processing. PMID:27012986

  13. 77 FR 14736 - Takes of Marine Mammals Incidental to Specified Activities; Pile Placement for Fishermen's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ..., Beaufort sea state, cloud cover, and visibility). In the unanticipated event that the specified activity...; Water depth; Environmental conditions (e.g., wind speed and direction, Beaufort sea state, cloud...

  14. Manipulation of D2 receptors with quinpirole and sulpiride affects locomotor activity before spatial behavior of rats in an active place avoidance task.

    PubMed

    Stuchlik, Ales; Rehakova, Lenka; Rambousek, Lukas; Svoboda, Jan; Vales, Karel

    2007-06-01

    Dopamine-mediated neurotransmission is widely studied with respect to motivation, motor activity and cognitive processes. The aim of the present study was to evaluate the role of D2 receptors in the behavior of rats in the active allothetic place avoidance (AAPA) task. D2 receptor agonist quinpirole and antagonist sulpiride were administered intraperitoneally 20min prior to behavioral testing. Administration of quinpirole led to dose-dependent increase of locomotion; the spatial efficiency was spared across the dose range studied (0.05-1.0mg/kg). In contrast, sulpiride decreased locomotor activity at a dose not influencing spatial efficiency (60mg/kg); the highest dose of sulpiride (100mg/kg) caused a deficit in both locomotor and spatial behaviors. The results suggest a relatively lesser importance of D2 receptors for spatial efficiency in the AAPA task, with a predominant influence of D2 receptor ligands on motor activity. PMID:17360063

  15. Sanctified Places

    ERIC Educational Resources Information Center

    Harnisch, Cynthia S.

    2010-01-01

    Cynthia Harnisch shares her unique perspective on the revered place that museums and community arts organizations occupy in the lives of the people they serve. She relates how, as vice president of the Autry National Center in 1994, she came to be introduced to Inner-City Arts and through that introduction discovered a new respect and recognition…

  16. Secret Places.

    ERIC Educational Resources Information Center

    Ridolfi, Kerry

    1997-01-01

    Argues that children are as deep as the ocean, with secret places inside of them waiting to be opened. Notes that it is powerful for students to learn they can make sense of the world through words, and describes inviting them into poetry as they read poetry, create poetry packets, and write and revise poems. (SR)

  17. 75 FR 74687 - Takes of Marine Mammals Incidental to Specified Activities; Construction of the Parsons Slough...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-01

    ... regulations, NMFS issued a notice in the Federal Register on October 5, 2010 (75 FR 61432), requesting... of the specified activity may be found in NMFS' proposed IHA notice in the Federal Register (75 FR... October 5, 2010 (75 FR 61432). During the 30-day public comment period, NMFS received comments from...

  18. Student's Reflections on Their Learning and Note-Taking Activities in a Blended Learning Course

    ERIC Educational Resources Information Center

    Nakayama, Minoru; Mutsuura, Kouichi; Yamamoto, Hiroh

    2016-01-01

    Student's emotional aspects are often discussed in order to promote better learning activity in blended learning courses. To observe these factors, course participant's self-efficacy and reflections upon their studies were surveyed, in addition to the surveying of the metrics of student's characteristics during a Bachelor level credit course.…

  19. 76 FR 46724 - Takes of Marine Mammals Incidental to Specified Activities; Seabird and Pinniped Research...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ... the census. NMFS outlined the purpose of the program in the Notice of Proposed IHA (76 FR 30311, May 25, 2011). The activities to be conducted have not changed between the Notice of Proposed IHA (76 FR... the pinniped and seabird research, NMFS refers the reader to the Notice of Proposed IHA (76 FR...

  20. 78 FR 40698 - Takes of Marine Mammals Incidental to Specified Activities; Office of Naval Research Acoustic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-08

    ... complete on March 7, 2013. On April 2, 2013, NMFS published a Federal Register notice (78 FR 19652... activity was provided in the proposed IHA (78 FR 19652, April 2, 2013). Comments and Responses A notice of... April 2, 2013 (78 FR 19652). During the 30-day public comment period, we received comments from...

  1. 77 FR 49412 - Takes of Marine Mammals Incidental to Specified Activities; Navy Research, Development, Test and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-16

    ... characteristics that determine the sound's speed through the water will change with depth, season, geographic...-20 test activities is provided in the Federal Register for the proposed IHA (77 FR 12010; February 28... and proposed authorization was published on February 28, 2012 (77 FR 12010). During the 30-day...

  2. 78 FR 72655 - Taking of Marine Mammals Incidental to Specified Activities; Bremerton Ferry Terminal Wingwall...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-03

    ... activities (78 FR 36527; June 18, 2013). The IHA covers the duration between September 1, 2013, and August 31... designating critical habitat for the Southern Resident killer whale DPS (71 FR 69054). Both Puget Sound and... than 20 feet deep relative to extreme high water are not designated as critical habitat (71 FR...

  3. 77 FR 39999 - Takes of Marine Mammals Incidental to Specified Activities; Pile Placement for Fishermen's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-06

    ..., NMFS issued a notice in the Federal Register on March 13, 2012 (77 FR 14736), requesting comments from... specified activity may be found in NMFS' proposed IHA notice in the Federal Register (77 FR 14736, March 13... FR 14736). During the 30-day public comment period, the Marine Mammal Commission...

  4. 76 FR 67419 - Takes of Marine Mammals Incidental to Specified Activities; Piling and Structure Removal in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-01

    ..., 2010, through February 28, 2011 (75 FR 67951). The specified activity includes all or part of the... (76 FR 56172). A complete description of the action was included in that notice and will not be... September 12, 2011, NMFS published a notice of proposed IHA (76 FR 56172) in response to DNR's request...

  5. Exciting New Take on a Classic: Crash Test Activity Puts the Egg in the Driver's Seat

    ERIC Educational Resources Information Center

    Board, Keith

    2011-01-01

    An excellent common activity in technology and engineering classes involves dropping an egg from a significant height in a protective device designed and built by students. This article describes how the author uses the classic "egg drop" as an inspiration to have students modify a small crash test vehicle that speeds down a track and crashes into…

  6. Exciting New Take on a Classic: Crash Testing Activity Puts the Egg in the Driver's Seat

    ERIC Educational Resources Information Center

    Board, Keith

    2011-01-01

    An excellent common activity in technology and engineering classes involves dropping an egg from a significant height in a protective device designed and built by students. This article describes how the author uses the classic "egg drop" as an inspiration to have students modify a small crash test vehicle that speeds down a track and crashes into…

  7. 76 FR 14924 - Takes of Marine Mammals Incidental to Specified Activities; Russian River Estuary Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-18

    ..., valid for a period of one year, on April 1, 2010 (75 FR 17382). Management activities include management... (61 FR 56138), SCWA and the Corps engaged NMFS in pre-consultation technical assistance to evaluate... disturbance impact over time. Management practices will be incrementally modified over the course of...

  8. 75 FR 38783 - Takes of Marine Mammals Incidental to Specified Activities; Manette Bridge Replacement in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ... the proposed IHA (75 FR 13502, March 22, 2010) and in the WSDOT's IHA application. No changes have... Register on March 22, 2010 (75 FR 13502). During the 30-day comment period, NMFS received a letter from the... activities, and ramp-up for pile driving) as described in NMFS' March 22, 2010 (75 FR 13502), notice of...

  9. 77 FR 2701 - Takes of Marine Mammals Incidental to Specified Activities; Pile Placement for ORPC Maine's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ... playbacks, ship and ice-breaking noise, vessel noise, acoustic harassment devices (AHDs), acoustic deterrent... install foundational piles to support an underwater tidal turbine unit. The turbine unit is approximately... driving activities after April 9 if they can demonstrate that noise levels caused by the impact hammer...

  10. Educating the Student Body: Taking Physical Activity and Physical Education to School

    ERIC Educational Resources Information Center

    Cook, Heather D., Ed.; Kohl , Harold W., III, Ed.

    2013-01-01

    Physical inactivity is a key determinant of health across the lifespan. A lack of activity increases the risk of heart disease, colon and breast cancer, diabetes mellitus, hypertension, osteoporosis, anxiety and depression and others diseases. Emerging literature has suggested that in terms of mortality, the global population health burden of…

  11. 76 FR 56172 - Takes of Marine Mammals Incidental to Specified Activities; Piling and Structure Removal in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-12

    ... February 28, 2011 (75 FR 67951). The specified activity includes all or part of the following actions... remnant log boom structures have been utilized as haul-out habitat for resting, pupping and molting for... Pier in the main operational area of the log dump, is composed of 6 log boom rows and 1...

  12. 76 FR 10564 - Takes of Marine Mammals Incidental to Specified Activities; St. George Reef Light Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-25

    ... notice for the proposed IHA (75 FR 80471 December 22, 2010). The planned activities have not changed... reader should refer to the proposed IHA notice (75 FR 8047, December 22, 2010). Comments and Responses... on December 22, 2010 (75 FR 80471). During the 30-day comment period, NMFS received a letter from...

  13. 76 FR 80891 - Small Takes of Marine Mammals Incidental to Specified Activities; Cape Wind's High Resolution...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-27

    ... and their occurrence in Nantucket Sound in the notice of the proposed IHA (76 FR 56735, September 14... IHA (76 FR 56735, September 14, 2011). The activities to be conducted have not changed between the IHA... proposed IHA notice (76 FR 56735, September 14, 2011), the application, and associated documents...

  14. Taking Active Learning into the Primary School: A Matter of New Practices?

    ERIC Educational Resources Information Center

    Stephen, Christine; Ellis, Jennifer; Martlew, Joan

    2010-01-01

    This paper examines the extension of active learning pedagogical practices familiar in preschool settings to the first class of primary school. Policy and practice guidance in the UK is advocating the benefits of experiential learning as a way of engaging young children as they move into primary school but for teachers this means a move to new…

  15. 78 FR 23746 - Takes of Marine Mammals Incidental to Specified Activities; Russian River Estuary Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-22

    ...In accordance with the regulations implementing the Marine Mammal Protection Act (MMPA) as amended, notification is hereby given that NMFS has issued an Incidental Harassment Authorization (IHA) to the Sonoma County Water Agency (SCWA) to incidentally harass, by Level B harassment only, three species of marine mammals during estuary management activities conducted at the mouth of the Russian......

  16. 76 FR 23306 - Takes of Marine Mammals Incidental to Specified Activities; Russian River Estuary Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-26

    ...In accordance with the regulations implementing the Marine Mammal Protection Act (MMPA) as amended, notification is hereby given that NMFS has issued an Incidental Harassment Authorization (IHA) to the Sonoma County Water Agency (SCWA) to incidentally harass, by Level B harassment only, three species of marine mammals during estuary management activities conducted at the mouth of the Russian......

  17. 75 FR 8677 - Takes of Marine Mammals Incidental to Specified Activities; Seabird and Pinniped Research...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... of the activity in the notice of the proposed IHA (74 FR 61109, November 23, 2009). No changes have... ft (457.2 m) above pinniped colonies to census northern elephant seal areas. The researchers will transit adjacent to a Steller sea lion haulout area to reach the northern elephant seal colony and...

  18. 77 FR 56613 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... Authorization (77 FR 19242, March 30, 2012). The Observatory's proposed activities have not changed between the... notice of the proposed IHA (77 FR 19242, March 30, 2012), the application, and Environmental Assessment... Register on March 30, 2012 (77 FR 19242). During the 30-day public comment period, we received...

  19. 76 FR 75525 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-02

    ... (76 FR 57959, September 19, 2011). The activities to be conducted have not changed between the... refer to the proposed IHA notice (76 FR 57959, September 19, 2011), the application and associated... Federal Register on September 19, 2011 (76 FR 57959). During the 30-day public comment period,...

  20. 77 FR 25693 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-01

    ... proposed IHA (77 FR 4765, January 31, 2012). The activities to be conducted have not changed between the... refer to the notice of the proposed IHA (77 FR 4765, January 31, 2012), the application, and associated... Federal Register on January 31, 2012 (77 FR 4765). During the 30-day public comment period, NMFS...

  1. The Dynamic Density Bottle: A Make-and-Take, Guided Inquiry Activity on Density

    ERIC Educational Resources Information Center

    Kuntzleman, Thomas S.

    2015-01-01

    An activity is described wherein students observe dynamic floating and sinking behavior of plastic pieces in various liquids. The liquids and solids are all contained within a plastic bottle; the entire assembly is called a "density bottle". After completing a series of experiments that guides students to think about the relative…

  2. 78 FR 36527 - Taking of Marine Mammals Incidental to Specified Activities; Construction at Bremerton Ferry...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-18

    ... Ferry Terminal is provided in the Federal Register notice for the proposed IHA (78 FR 11844; February 20... Federal Register notice for the proposed IHA (78 FR 11844; February 20, 2013). Please refer to that... FR 11844). That notice described, in detail, WSDOT's activity, the marine mammal species that may...

  3. Peroxisome Proliferator-Activated Receptor γ (PPARγ) and Ligand Choreography: Newcomers Take the Stage.

    PubMed

    Garcia-Vallvé, Santiago; Guasch, Laura; Tomas-Hernández, Sarah; del Bas, Josep Maria; Ollendorff, Vincent; Arola, Lluís; Pujadas, Gerard; Mulero, Miquel

    2015-07-23

    Thiazolidinediones (TZDs), such as rosiglitazone and pioglitazone, are peroxisome proliferator-activated receptor γ (PPARγ) full agonists that have been widely used in the treatment of type 2 diabetes mellitus. Despite the demonstrated beneficial effect of reducing glucose levels in the plasma, TZDs also induce several adverse effects. Consequently, the search for new compounds with potent antidiabetic effects but fewer undesired effects is an active field of research. Interestingly, the novel proposed mechanisms for the antidiabetic activity of PPARγ agonists, consisting of PPARγ Ser273 phosphorylation inhibition, ligand and receptor mutual dynamics, and the presence of an alternate binding site, have recently changed the view regarding the optimal characteristics for the screening of novel PPARγ ligands. Furthermore, transcriptional genomics could bring essential information about the genome-wide effects of PPARγ ligands. Consequently, facing the new mechanistic scenario proposed for these compounds is essential for resolving the paradoxes among their agonistic function, antidiabetic activities, and side effects and should allow the rational development of better and safer PPARγ-mediated antidiabetic drugs. PMID:25734377

  4. 77 FR 59904 - Takes of Marine Mammals Incidental to Specified Activities; Pile Driving for Honolulu Seawater...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ... implementing regulations, NMFS issued a notice in the Federal Register on July 24, 2012 (77 FR 43259... description of the specified activity may be found in NMFS' proposed IHA notice in the Federal Register (77 FR... and Responses A proposed IHA and request for public comment was published on July 24, 2012 (77...

  5. 76 FR 33705 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-09

    ... Register (76 FR 18167) disclosing the effects on marine mammals, making preliminary determinations and... for the proposed IHA (76 FR 18167, April 1, 2011). The activities to be conducted have not changed... reader should refer to the proposed IHA notice (76 FR 18167, April 1, 2011), the IHA application...

  6. 78 FR 34069 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-06

    ... notice of the proposed IHA (78 FR 17359, March 21, 2013). The seismic survey will not result in any... published a notice in the Federal Register (78 FR 17359) making preliminary determinations and proposing to... program in a previous notice for the proposed IHA (78 FR 17359, March 21, 2013). The activities to...

  7. 78 FR 47282 - Takes of Marine Mammals Incidental to Specified Activities; Navy Research, Development, Test and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ... June 6, 2013, NMFS published a notice in the Federal Register (78 FR 34047) making preliminary... testing activities was published in the Federal Register on June 6, 2013 (78 FR 34047). During the 30-day... detail in the Federal Register notice for the proposed IHA (78 FR 34047, June 6, 2013), as well as...

  8. 77 FR 6065 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ... notice in the Federal Register (75 FR 8652) with preliminary determinations and a proposed IHA. Ship... the Federal Register (76 FR 77782) disclosing the effects on marine mammals, making preliminary... in a previous notice for the proposed IHA (76 FR 77782, December 14, 2011). The activities to...

  9. 76 FR 38621 - Takes of Marine Mammals Incidental to Specified Activities; Marine Geophysical Survey in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    .... On May 6, 2011, NMFS published a notice in the Federal Register (76 FR 26255) disclosing the effects... notice for the proposed IHA (76 FR 26255, May 6, 2011). The activities to be conducted have not changed... reader should refer to the proposed IHA notice (76 FR 26255, May 6, 2011), the IHA application, EA,...

  10. 75 FR 4774 - Takes of Marine Mammals Incidental to Specified Activities; St. George Reef Light Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-29

    ... Specified Activities; St. George Reef Light Station Restoration and Maintenance on Northwest Seal Rock, in... the St. George Reef Lighthouse Preservation Society (SGRLPS), to incidentally harass, by Level B... INFORMATION: Background Section 101(a)(5)(D) of the MMPA (16 U.S.C. 1371 (a)(5)(D)) directs the Secretary...

  11. Neuroimaging supports behavioral personality assessment: Overlapping activations during reflective and impulsive risk taking.

    PubMed

    Pletzer, Belinda; M Ortner, Tuulia

    2016-09-01

    Personality assessment has been challenged by the fact that different assessment methods (implicit measures, behavioral measures and explicit rating scales) show little or no convergence in behavioral studies. In this neuroimaging study we address for the first time, whether different assessment methods rely on separate or overlapping neuronal systems. Fifty nine healthy adult participants completed two objective personality tests of risk propensity: the more implicit Balloon Analogue Risk Task (BART) and the more explicit Game of Dice Task (GDT). Significant differences in activation, as well as connectivity patterns between both tasks were observed. In both tasks, risky decisions yielded significantly stronger activations than safe decisions in the bilateral caudate, as well as the bilateral Insula. The finding of overlapping brain areas validates different assessment methods, despite their behavioral non-convergence. This suggests that neuroimaging can be an important tool of validation in the field of personality assessment. PMID:27373370

  12. Drug target identification using network analysis: Taking active components in Sini decoction as an example

    PubMed Central

    Chen, Si; Jiang, Hailong; Cao, Yan; Wang, Yun; Hu, Ziheng; Zhu, Zhenyu; Chai, Yifeng

    2016-01-01

    Identifying the molecular targets for the beneficial effects of active small-molecule compounds simultaneously is an important and currently unmet challenge. In this study, we firstly proposed network analysis by integrating data from network pharmacology and metabolomics to identify targets of active components in sini decoction (SND) simultaneously against heart failure. To begin with, 48 potential active components in SND against heart failure were predicted by serum pharmacochemistry, text mining and similarity match. Then, we employed network pharmacology including text mining and molecular docking to identify the potential targets of these components. The key enriched processes, pathways and related diseases of these target proteins were analyzed by STRING database. At last, network analysis was conducted to identify most possible targets of components in SND. Among the 25 targets predicted by network analysis, tumor necrosis factor α (TNF-α) was firstly experimentally validated in molecular and cellular level. Results indicated that hypaconitine, mesaconitine, higenamine and quercetin in SND can directly bind to TNF-α, reduce the TNF-α-mediated cytotoxicity on L929 cells and exert anti-myocardial cell apoptosis effects. We envisage that network analysis will also be useful in target identification of a bioactive compound. PMID:27095146

  13. Drug target identification using network analysis: Taking active components in Sini decoction as an example.

    PubMed

    Chen, Si; Jiang, Hailong; Cao, Yan; Wang, Yun; Hu, Ziheng; Zhu, Zhenyu; Chai, Yifeng

    2016-01-01

    Identifying the molecular targets for the beneficial effects of active small-molecule compounds simultaneously is an important and currently unmet challenge. In this study, we firstly proposed network analysis by integrating data from network pharmacology and metabolomics to identify targets of active components in sini decoction (SND) simultaneously against heart failure. To begin with, 48 potential active components in SND against heart failure were predicted by serum pharmacochemistry, text mining and similarity match. Then, we employed network pharmacology including text mining and molecular docking to identify the potential targets of these components. The key enriched processes, pathways and related diseases of these target proteins were analyzed by STRING database. At last, network analysis was conducted to identify most possible targets of components in SND. Among the 25 targets predicted by network analysis, tumor necrosis factor α (TNF-α) was firstly experimentally validated in molecular and cellular level. Results indicated that hypaconitine, mesaconitine, higenamine and quercetin in SND can directly bind to TNF-α, reduce the TNF-α-mediated cytotoxicity on L929 cells and exert anti-myocardial cell apoptosis effects. We envisage that network analysis will also be useful in target identification of a bioactive compound. PMID:27095146

  14. Mixing it up: Corals take an active role in mass transport

    NASA Astrophysics Data System (ADS)

    Fernandez, Vicente; Shapiro, Orr; Brumley, Douglas; Garren, Melissa; Guasto, Jeffrey; Kramarski-Winter, Esti; Vardi, Assaf; Stocker, Roman

    2014-11-01

    The growth and health of reef-building corals are limited by corals' ability to exchange nutrients and oxygen with the surrounding, sometimes quiescent, seawater. Mass transport in coral systems has long been considered to occur passively as a result of molecular diffusion and the ambient fluid flow over the coral. Through a combination of microscale visualization experiments and numerical modeling, we demonstrate instead that motile cilia densely covering the coral surface - previously thought to serve cleaning and feeding purposes- actively stir the coral boundary layer by generating persistent vortices above the coral surface. This active mixing was observed over a variety of corals with differing surface geometries. We have quantified the contribution of ciliary surface vortices to mass transport, finding oxygen flux enhancements of 2 to 3 orders of magnitude under environmentally relevant ambient flow conditions. These results reveal a new, active role of the coral animal in regulating its mass transport by engineering its local hydrodynamic environment, an ability that may have an important role in the evolutionary success of reef corals.

  15. Willingness to Take PrEP and Potential for Risk Compensation Among Highly Sexually Active Gay and Bisexual Men.

    PubMed

    Grov, Christian; Whitfield, Thomas H F; Rendina, H Jonathon; Ventuneac, Ana; Parsons, Jeffrey T

    2015-12-01

    Once-daily Truvada (Emtricitabine/Tenofovir) as a method of pre-exposure prophylaxis (PrEP) is one of the most promising biomedical interventions to eliminate new HIV infections; however, uptake among gay, bisexual, and other men who have sex with men has been slow amidst growing concern in popular/social media that PrEP use will result in reduced condom use (i.e., risk compensation). We investigated demographic, behavioral, and psychosocial differences in willingness to use PrEP as well as the perceived impact of PrEP on participants' condom use in a sample of 206 highly sexually active HIV-negative gay and bisexual men. Nearly half (46.1 %) said they would be willing to take PrEP if it were provided at no cost. Although men willing to take PrEP (vs. others) reported similar numbers of recent casual male partners (<6 weeks), they had higher odds of recent receptive condomless anal sex (CAS)-i.e., those already at high risk of contracting HIV were more willing to take PrEP. Neither age, race/ethnicity, nor income were associated with willingness to take PrEP, suggesting equal acceptability among subpopulations that are experiencing disparities in HIV incidence. There was limited evidence to suggest men would risk compensate. Only 10 % of men who had not engaged in recent CAS felt that PrEP would result in them starting to have CAS. Men who had not tested for HIV recently were also significantly more likely than others to indicate willingness to take PrEP. Offering PrEP to men who test infrequently may serve to engage them more in routine HIV/STI testing and create a continued dialogue around sexual health between patient and provider in order to prevent HIV infection. PMID:25735243

  16. Dyadic social interaction inhibits cocaine-conditioned place preference and the associated activation of the accumbens corridor

    PubMed Central

    Pinheiro, Barbara S.

    2015-01-01

    Impaired social interaction is a hallmark symptom of many psychiatric disorders. In substance use disorders, impaired social interaction is triply harmful (a) because addicts increasingly prefer the drug of abuse to the natural reward of drug-free social interaction, thus worsening the progression of the disease by increasing their drug consumption, (b) because treatment adherence and, consequently, treatment success itself depends on the ability of the recovering addict to maintain social interaction and adhere to treatment, and (c) because socially interacting with an individual suffering from a substance use disorder may be harmful for others. Helping the addict reorient his/her behavior away from the drug of abuse toward social interaction would therefore be of considerable therapeutic benefit. This article reviews our work on the neural basis of such a reorientation from cocaine, as a prototypical drug of abuse, toward dyadic (i.e. one-to-one) social interaction and compares our findings with the effects of other potentially beneficial interventions, that is, environmental enrichment or paired housing, on the activation of the accumbens and other brain regions involved in behavior motivated by drugs of abuse or nondrug stimuli. Our experimental models are based on the conditioned place preference paradigm. As the therapeutically most promising finding, only four 15 min episodes of dyadic social interaction were able to inhibit both the subsequent reacquisition/re-expression of preference for cocaine and the neural activation associated with this behavior, that is, an increase in the expression of the immediate early gene Early Growth Response protein 1 (EGR1, Zif268) in the nucleus accumbens, basolateral and central amygdala, and the ventral tegmental area. The time spent in the cocaine-associated conditioning compartment was correlated with the density of EGR1-activated neurons not only in the medial core (AcbCm) and medial shell (AcbShm) of the nucleus

  17. Conditioned place preference and locomotor activity in response to methylphenidate, amphetamine and cocaine in mice lacking dopamine D4 receptors

    SciTech Connect

    Thanos, P.K.; Thanos, P.K.; Bermeo, C.; Rubinstein, M.; Suchland, K.L.; Wang, G.-J.; Grandy, D.K.; Volkow, N.D.

    2010-05-01

    Methylphenidate (MP) and amphetamine (AMPH) are the most frequently prescribed medications for the treatment of attention-deficit/hyperactivity disorder (ADHD). Both drugs are believed to derive their therapeutic benefit by virtue of their dopamine (DA)-enhancing effects, yet an explanation for the observation that some patients with ADHD respond well to one medication but not to the other remains elusive. The dopaminergic effects of MP and AMPH are also thought to underlie their reinforcing properties and ultimately their abuse. Polymorphisms in the human gene that codes for the DA D4 receptor (D4R) have been repeatedly associated with ADHD and may correlate with the therapeutic as well as the reinforcing effects of responses to these psychostimulant medications. Conditioned place preference (CPP) for MP, AMPH and cocaine were evaluated in wild-type (WT) mice and their genetically engineered littermates, congenic on the C57Bl/6J background, that completely lack D4Rs (knockout or KO). In addition, the locomotor activity in these mice during the conditioning phase of CPP was tested in the CPP chambers. D4 receptor KO and WT mice showed CPP and increased locomotor activity in response to each of the three psychostimulants tested. D4R differentially modulates the CPP responses to MP, AMPH and cocaine. While the D4R genotype affected CPP responses to MP (high dose only) and AMPH (low dose only) it had no effects on cocaine. Inasmuch as CPP is considered an indicator of sensitivity to reinforcing responses to drugs these data suggest a significant but limited role of D4Rs in modulating conditioning responses to MP and AMPH. In the locomotor test, D4 receptor KO mice displayed attenuated increases in AMPH-induced locomotor activity whereas responses to cocaine and MP did not differ. These results suggest distinct mechanisms for D4 receptor modulation of the reinforcing (perhaps via attenuating dopaminergic signalling) and locomotor properties of these stimulant drugs

  18. What is taking place in science classrooms?: A case study analysis of teaching and learning in seventh-grade science of one Alabama school and its impact on African American student learning

    NASA Astrophysics Data System (ADS)

    Norman, Lashaunda Renea

    This qualitative case study investigated the teaching strategies that improve science learning of African American students. This research study further sought the extent the identified teaching strategies that are used to improve African American science learning reflect culturally responsive teaching. Best teaching strategies and culturally responsive teaching have been researched, but there has been minimal research on the impact that both have on science learning, with an emphasis on the African American population. Consequently, the Black-White achievement gap in science persists. The findings revealed the following teaching strategies have a positive impact on African American science learning: (a) lecture-discussion, (b) notetaking, (c) reading strategies, (d) graphic organizers, (e) hands-on activities, (f) laboratory experiences, and (g) cooperative learning. Culturally responsive teaching strategies were evident in the seventh-grade science classrooms observed. Seven themes emerged from this research data: (1) The participating teachers based their research-based teaching strategies used in the classroom on all of the students' learning styles, abilities, attitudes towards science, and motivational levels about learning science, with no emphasis on the African American student population; (2) The participating teachers taught the state content standards simultaneously using the same instructional model daily, incorporating other content areas when possible; (3) The participating African American students believed their seventh-grade science teachers used a variety of teaching strategies to ensure science learning took place, that science learning was fun, and that science learning was engaging; (4) The participating African American students genuinely liked their teacher; (5) The participating African American students revealed high self-efficacy; (6) The African American student participants' parents value education and moved to Success Middle School

  19. An Assay of Measuring Platelet Reactivity Using Monoclonal Antibody against Activated Platelet Glycoprotein IIb/IIIa in Patients Taking Clopidogrel

    PubMed Central

    Choi, Joon-Hyouk; Kim, Song-Yi; Kim, Ki-Seok; Kim, Young Ree; Kang, Sung Ha

    2015-01-01

    Background and Objectives Residual platelet reactivity in patients who are taking clopidogrel is commonly measured with VerifyNow assay, which is based on the principle of light transmission aggregometry. However, to evaluate the residual platelet reactivity, it would be more accurate if the reactivity of platelet glycoprotein (GP) IIb/IIIa is directly monitored. In this study, PAC1, a monoclonal antibody against activated platelet GP IIb/IIIa, was used to measure the residual platelet reactivity. Subjects and Methods Twenty seven patients with coronary artery disease taking clopidogrel were enrolled. Platelets in whole blood were stained with fluorescein isothiocyanate (FITC)-conjugated PAC1. Mean fluorescence intensity (MFI) and % positive platelets (PP) were measured with flow cytometry, and the binding index (BI; MFI × %PP/100) was calculated. P2Y12 reaction unit (PRU) and % inhibition of VerifyNow assay were also measured in the usual manner. Results PRU of VerifyNow assay correlated significantly with MFI, %PP, and BI at 10 µM (r=0.59, 0.73, and 0.60, respectively, all p<0.005) and 20 µM of adenosine diphosphate (ADP; r=0.61, 0.75, and 0.63, respectively, all p<0.005). The % inhibition also correlated significantly with MFI, %PP, and BI at 10 µM (r=-0.60, -0.69, and -0.59, respectively, all p<0.005) and 20 µM of ADP (r=-0.63, -0.71, and -0.62, respectively, all p<0.005). Conclusion Direct measurements of the reactivity of platelet GP IIb/IIIa were feasible using PAC1 and flow cytometry in patients taking clopidogrel. Further clinical studies are required to determine the cut-off values which would define high residual platelet reactivity in patients on this treatment protocol. PMID:26413105

  20. The use of parent involved take-home science activities during student teaching: Understanding the challenges of implementation

    NASA Astrophysics Data System (ADS)

    Zarazinski, Jill

    The purpose of this study was to identify student teachers use and implementation of Science in a Bag when it was no longer a required course-based assessment. This take-home science activity acted as the elaboration component of the 5Es lesson teacher candidates designed and taught in the classroom, utilized household items, and directly involved parents in their child's education. The purposeful sample was comprised of six teacher candidates during their student teaching practicum, the last semester of the childhood education teacher certification program. This collective case study centered on student teachers' use of the focused activity, Science in a Bag, in order to gain knowledge of challenges faced in applying take-home science kits and working with parents. Data collection was comprised of student teacher and parent interviews, candidate reflections, as well as in-class observations and discussions carried out during weekly seminars. Data collection occurred throughout the seven-week student teaching practicum. The four research questions were: 1) What factors do teacher candidates identify as interfering with their ability to implement Science in a Bag during student teaching placements? 2) What factors do teacher candidates identify as enhancing their ability to carry out Science in a Bag? 3) What forms of support do teacher candidates believe are important to their success in implementing Science in a Bag during student teaching? 4) How do teacher candidates deal with obstacles when implementing Science in a Bag? Despite the fact that no student teacher was prohibited from implementing Science in a Bag, the level to which candidates valued and utilized this instructional strategy varied compared to how they were taught and practiced it during the science methods course. Some student teachers attempted to hide their feelings toward Science in a Bag, however their actions revealed that they were simply carrying out the instructional strategy because they

  1. A woman's rightful place?

    PubMed

    1993-04-01

    Rural development projects in sub-Saharan Africa tend not to succeed because they do not consider women's role and their significance, even though women constitute 70% of agricultural workers, 80% of food producers, 100% of people who prepare meals, and 60-90% do food marketing. Development specialists ignore women because they are not involved in political activities and in decision making. As long as women and women's contributions are not considered, rural development projects will remain inefficient and development will not take place. Thus, projects must include women as agents and beneficiaries of development in key sectors of the economy. Rural development specialists must also consider the effect male labor emigration has on rural women. For example, drought has forced many men to leave their villages, leaving a work force consisting of 95% women to fight desertification. All too often, women have no or limited land ownership rights, thereby keeping them from improving the land, e.g., planting perennial fruit crops. They also tend to be hired hands rather than food producers. They cannot obtain bank loans because they do not own land, and because they are often illiterate (over 90% female illiteracy in 28 African countries), they can neither understand nor complete bank loan forms. Rural development projects further alienate women by aiming training programs to men or by using male agricultural extension agents. Women react to this alienation by rejecting projects that do not benefit them and follow more profitable activities which sometimes interfere with projects. Thus, rural development programs need to invest in women to ensure viable and efficient sustainable development. PMID:12344988

  2. Privileged Girls: The Place of Femininity and Femininity in Place

    ERIC Educational Resources Information Center

    Fahey, Johannah

    2014-01-01

    Constructions of femininity and attendant notions of feminism are being produced in different ways in different places around the world. This is a complicated global process that cannot be reduced to analyses that take place in nation states. This paper seeks to respond to and enhance Angela McRobbie's compelling argument about understandings…

  3. Taking antacids

    MedlinePlus

    ... magnesium may cause diarrhea. Brands with calcium or aluminum may cause constipation. Rarely, brands with calcium may ... you take large amounts of antacids that contain aluminum, you may be at risk for calcium loss, ...

  4. Taking Time

    ERIC Educational Resources Information Center

    Perry, Tonya

    2004-01-01

    The opportunity for students to successfully complete the material increases when teachers take time and care about what they are reading. Students can read the contents of a text successfully if they keep their thoughts moving and ideas developing.

  5. Risk-Taking Behavior in a Computerized Driving Task: Brain Activation Correlates of Decision-Making, Outcome, and Peer Influence in Male Adolescents

    PubMed Central

    Vorobyev, Victor; Kwon, Myoung Soo; Moe, Dagfinn; Parkkola, Riitta; Hämäläinen, Heikki

    2015-01-01

    Increased propensity for risky behavior in adolescents, particularly in peer groups, is thought to reflect maturational imbalance between reward processing and cognitive control systems that affect decision-making. We used functional magnetic resonance imaging (fMRI) to investigate brain functional correlates of risk-taking behavior and effects of peer influence in 18–19-year-old male adolescents. The subjects were divided into low and high risk-taking groups using either personality tests or risk-taking rates in a simulated driving task. The fMRI data were analyzed for decision-making (whether to take a risk at intersections) and outcome (pass or crash) phases, and for the influence of peer competition. Personality test-based groups showed no difference in the amount of risk-taking (similarly increased during peer competition) and brain activation. When groups were defined by actual task performance, risk-taking activated two areas in the left medial prefrontal cortex (PFC) significantly more in low than in high risk-takers. In the entire sample, risky decision-specific activation was found in the anterior and dorsal cingulate, superior parietal cortex, basal ganglia (including the nucleus accumbens), midbrain, thalamus, and hypothalamus. Peer competition increased outcome-related activation in the right caudate head and cerebellar vermis in the entire sample. Our results suggest that the activation of the medial (rather than lateral) PFC and striatum is most specific to risk-taking behavior of male adolescents in a simulated driving situation, and reflect a stronger conflict and thus increased cognitive effort to take risks in low risk-takers, and reward anticipation for risky decisions, respectively. The activation of the caudate nucleus, particularly for the positive outcome (pass) during peer competition, further suggests enhanced reward processing of risk-taking under peer influence. PMID:26052943

  6. Risk-Taking Behavior in a Computerized Driving Task: Brain Activation Correlates of Decision-Making, Outcome, and Peer Influence in Male Adolescents.

    PubMed

    Vorobyev, Victor; Kwon, Myoung Soo; Moe, Dagfinn; Parkkola, Riitta; Hämäläinen, Heikki

    2015-01-01

    Increased propensity for risky behavior in adolescents, particularly in peer groups, is thought to reflect maturational imbalance between reward processing and cognitive control systems that affect decision-making. We used functional magnetic resonance imaging (fMRI) to investigate brain functional correlates of risk-taking behavior and effects of peer influence in 18-19-year-old male adolescents. The subjects were divided into low and high risk-taking groups using either personality tests or risk-taking rates in a simulated driving task. The fMRI data were analyzed for decision-making (whether to take a risk at intersections) and outcome (pass or crash) phases, and for the influence of peer competition. Personality test-based groups showed no difference in the amount of risk-taking (similarly increased during peer competition) and brain activation. When groups were defined by actual task performance, risk-taking activated two areas in the left medial prefrontal cortex (PFC) significantly more in low than in high risk-takers. In the entire sample, risky decision-specific activation was found in the anterior and dorsal cingulate, superior parietal cortex, basal ganglia (including the nucleus accumbens), midbrain, thalamus, and hypothalamus. Peer competition increased outcome-related activation in the right caudate head and cerebellar vermis in the entire sample. Our results suggest that the activation of the medial (rather than lateral) PFC and striatum is most specific to risk-taking behavior of male adolescents in a simulated driving situation, and reflect a stronger conflict and thus increased cognitive effort to take risks in low risk-takers, and reward anticipation for risky decisions, respectively. The activation of the caudate nucleus, particularly for the positive outcome (pass) during peer competition, further suggests enhanced reward processing of risk-taking under peer influence. PMID:26052943

  7. Normalization of EEG activity among previously institutionalized children placed into foster care: A 12-year follow-up of the Bucharest Early Intervention Project.

    PubMed

    Vanderwert, Ross E; Zeanah, Charles H; Fox, Nathan A; Nelson, Charles A

    2016-02-01

    Extreme social and cognitive deprivation as a result of institutional care has profound effects on developmental outcomes across multiple domains for many abandoned or orphaned children. The Bucharest Early Intervention Project (BEIP) examines the outcomes for children originally placed in institutions who were assessed comprehensively and then randomized to foster care (FCG) or care as usual (CAUG) and followed longitudinally. Here we report on the brain electrical activity (electroencephalogram: EEG) of 12-year-old children enrolled in the BEIP. Previous reports suggested improvement in resting EEG activity for the group of children placed in the foster care intervention, particularly those placed before 24 months of age compared to children who were randomized to CAUG or those placed into families after this age. At 12 years, differences between those in the FCG and those in the CAUG persist in the alpha band (8-13 Hz), but not in higher frequency bands (i.e. in the beta band; 15-30 Hz), except in those children placed into the FCG who remained in high quality care environments over the course of the study. These findings highlight the importance of maintaining a stable high quality caregiving environment, particularly for children exposed to early psychosocial deprivation, for promoting healthy brain development. PMID:26724564

  8. A Sense of Place

    NASA Technical Reports Server (NTRS)

    2005-01-01

    [figure removed for brevity, see original site] Labeled image for A Sense of Place

    NASA's Mars Exploration rover Spirit continues to descend along the east side of the 'Columbia Hills,' taking panoramic views of surrounding terrain at the end of each day of driving. This helps members of the science team get a sense of place before proceeding, kind of the way a hiker pauses now and then to view the scenery. Scientists and engineers use panoramas like this to select interesting rocks and soils for further study and to plan a safe path for the rover.

    In this image mosaic, Spirit is pausing to take a good look around while descending due east toward a ridge nicknamed 'Haskin Ridge.' Before driving the rest of the way down, Spirit will take a panoramic image of the large, deep basin to the left of the ridge, labeled 'East Basin,' which was not visible from the summit. A longer-term destination is the prominent, round, platform-like feature labeled 'Home Plate.'

    This 360-degree panorama was assembled from images Spirit took with its navigation camera on the 651st martian day, or sol (Nov. 2, 2005), of its exploration of Gusev Crater on Mars. The view is presented in a cylindrical projection with geometric seam correction.

  9. The use of parent involved take-home science activities during student teaching: Understanding the challenges of implementation

    NASA Astrophysics Data System (ADS)

    Zarazinski, Jill

    The purpose of this study was to identify student teachers use and implementation of Science in a Bag when it was no longer a required course-based assessment. This take-home science activity acted as the elaboration component of the 5Es lesson teacher candidates designed and taught in the classroom, utilized household items, and directly involved parents in their child's education. The purposeful sample was comprised of six teacher candidates during their student teaching practicum, the last semester of the childhood education teacher certification program. This collective case study centered on student teachers' use of the focused activity, Science in a Bag, in order to gain knowledge of challenges faced in applying take-home science kits and working with parents. Data collection was comprised of student teacher and parent interviews, candidate reflections, as well as in-class observations and discussions carried out during weekly seminars. Data collection occurred throughout the seven-week student teaching practicum. The four research questions were: 1) What factors do teacher candidates identify as interfering with their ability to implement Science in a Bag during student teaching placements? 2) What factors do teacher candidates identify as enhancing their ability to carry out Science in a Bag? 3) What forms of support do teacher candidates believe are important to their success in implementing Science in a Bag during student teaching? 4) How do teacher candidates deal with obstacles when implementing Science in a Bag? Despite the fact that no student teacher was prohibited from implementing Science in a Bag, the level to which candidates valued and utilized this instructional strategy varied compared to how they were taught and practiced it during the science methods course. Some student teachers attempted to hide their feelings toward Science in a Bag, however their actions revealed that they were simply carrying out the instructional strategy because they

  10. A neural mass model of place cell activity: theta phase precession, replay and imagination of never experienced paths.

    PubMed

    Cona, Filippo; Ursino, Mauro

    2015-02-01

    Recent results on hippocampal place cells show that the replay of behavioral sequences does not simply reflect previously experienced trajectories, but may also occur in the reverse direction, or may even include never experienced paths. In order to elucidate the possible mechanisms at the basis of this phenomenon, we have developed a model of sequence learning. The present model consists of two layers of place cell units. Long-range connections among units implement heteroassociation between the two layers, trained with a temporal Hebb rule. The network was trained assuming that a virtual rat moves within a virtual maze. This training leads to the formation of bidirectional synapses between the two layers, i.e. synapses connecting a neuron both with its previous and subsequent element in the path. Subsequently, two distinct conditions were simulated with the trained network. During an exploratory phase, characterized by a similar consideration to the external environment and to the internal representation, the model simulates the occurrence of theta precession in the forward path and the temporal compression. During an imagination phase, when there is no consideration to the external location, the model produces trains of gamma oscillations, without the presence of a theta rhythm, and simulates the occurrence of both direct and reverse replay, and the imagination of never experienced paths. The new paths are built by combining bunches of previous trajectories. The main mechanisms at the basis of this behavior are explained in detail, and lines for future improvements (e.g., to simulate preplay) are discussed. PMID:25284339

  11. Mountain Hike North of Big Cottonwood Canyon Road, Begining at the S-Turn at Mill B., Near Hidden Falls, and Taking Trail Leading to Mt. Raymond and Other Intersting Places.

    NASA Astrophysics Data System (ADS)

    McDonald, Keith L.

    2004-11-01

    Our first objective is to leave the highway via Mill B North Fork by taking the Big Cottonwood Canyon trail that leads to Maxfield Basin, where 3 trails intersect, just s. of Mount Raymond (Elev. 10,241 ft.) the n. trail takes us down to the Mill Creek Canyon Road, at about 1 mi. (+) east of intersection with Church Park Picnic Ground road. At Maxfield Basin, again, the east trail skirts around Mt. Raymond and has another intersection with a trail running n. thru the area of Gobblers Knob (elev. 10,246 ft.), to White Fir Pass and turns w. at Bowman Fk. until it connects with Porter Fork and then the Mill Creek Road. The remaining trail at Mill A Basin, just e. of Mount Raymond, long before Gobblers Knob is seen, runs east past a spring, and connects to Butler Fork (which begins at 3.775 mi., measured along highway from Mill B, North Fork), which leads directly to Dog Lake. Evidently both Dog Lake and Lake Desolation (changing U.S. Geological Survey maps from Mount Aire, Utah to Park City West, Utah) have connected outlets, at least during certain times of the year. Following the trail s. e. (down) that follows near Summit Co. and Salt Lake County, we pass by the radio transmitters shown on Park City, West, Utah, map and finally enter the Brighton, Utah map with Scott Hill, Scott Pass, the important highway leading to Midway Reservoir, and beyond, Bloods Lake ( 9500 ft.), Clayton Peak (10,721 ft.) and Lake Lackawaxen ( 9980 ft.), our final destination showing through. One may easily walk the distance to lake Lackawaxen from Bloods Lake by staying south of the ridgecrest and by following the hollow down for a while. This completes our destination. Recall that the main roadway here was already passed over about 1/2 mile n. of Bloods Lake; this thoroughfare has its beginning at about 0.4 miles below (or North) of the Brighton Loop, where the road to city of Midway leaves the main Big Cottonwood Highway going n. and runs e., on the average, going past Midway Reservoir

  12. Places where preschoolers are (in)active: An observational study on Latino preschoolers and their parents using objective measures

    Technology Transfer Automated Retrieval System (TEKTRAN)

    To combat the disproportionately higher risk of childhood obesity in Latino preschool-aged children, multilevel interventions targeting physical (in)activity are needed. These require the identification of environmental and psychosocial determinants of physical (in)activity for this ethnic group. Th...

  13. Winner-take-all networks - Time-based versus activation-based mechanisms for various selection goals

    NASA Technical Reports Server (NTRS)

    Barnden, John; Srinivas, Kankanahalli; Daharmavaratha, Dronpadi

    1990-01-01

    As an alternative to conventional winner-take-all mechanisms, the paper presents a temporal winner-take-all mecahnism with O(n) space complexity and roughly O(log n) time complexity. It exploits systematic and stochastic differences between time delays within different units and connections.

  14. 75 FR 5575 - Taking and Importing Marine Mammals; Navy Training Activities Conducted in the Gulf of Alaska

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-03

    ... National Oceanic and Atmospheric Administration RIN 0648-XU14 Taking and Importing Marine Mammals; Navy...), National Oceanic and Atmospheric Administration (NOAA), Commerce. ACTION: Notice; receipt of application... pressure from underwater detonations. The Navy requests authorization to take individuals of 20 species...

  15. Factors impacting the activity of 2,4-diacetylphloroglucinol-producing Pseudomonas fluorescens against take-all of wheat

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Take-all, caused by Gaeumannomyces graminis var. tritici, is an important soilborne disease of wheat worldwide. Pseudomonas fluorescens producing the antibiotic 2,4-diacetylphloroglucinol (2,4-DAPG) are biocontrol agents of take-all and provide natural suppression of the disease during wheat monocul...

  16. 75 FR 54095 - Takes of Marine Mammals Incidental to Specified Activities; Low-Energy Marine Seismic Survey in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-03

    ...NMFS has received an application from the Scripps Institution of Oceanography (SIO) of the University of California for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to conducting a low-energy marine seismic survey. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on its proposal to issue an IHA to SIO to take, by......

  17. A place for play? The influence of the home physical environment on children’s physical activity and sedentary behaviour

    PubMed Central

    2013-01-01

    The home environment is an important influence on the sedentary behaviour and physical activity of children, who have limited independent mobility and spend much of their time at home. This article reviews the current evidence regarding the influence of the home physical environment on the sedentary behaviour and physical activity of children aged 8–14 years. A literature search of peer reviewed articles published between 2005 and 2011 resulted in 38 observational studies (21 with activity outcomes, 23 with sedentary outcomes) and 11 experimental studies included in the review. The most commonly investigated behavioural outcomes were television watching and moderate to vigorous physical activity. Media equipment in the home and to a lesser extent the bedroom were positively associated with children’s sedentary behaviour. Physical activity equipment and the house and yard were not associated with physical activity, although environmental measures were exclusively self-reported. On the other hand, physical activity equipment was inversely associated with sedentary behaviours in half of studies. Observational studies that investigated the influence of the physical and social environment within the home space, found that the social environment, particularly the role of parents, was important. Experimental studies that changed the home physical environment by introducing a television limiting device successfully decreased television viewing, whereas the influence of introducing an active video game on activity outcomes was inconsistent. Results highlight that the home environment is an important influence on children’s sedentary behaviour and physical activity, about which much is still unknown. While changing or controlling the home physical environment shows promise for reducing screen based sedentary behaviour, further interventions are needed to understand the broader impact of these changes. Future studies should prioritise investigating the influence of the

  18. A place for play? The influence of the home physical environment on children's physical activity and sedentary behaviour.

    PubMed

    Maitland, Clover; Stratton, Gareth; Foster, Sarah; Braham, Rebecca; Rosenberg, Michael

    2013-01-01

    The home environment is an important influence on the sedentary behaviour and physical activity of children, who have limited independent mobility and spend much of their time at home. This article reviews the current evidence regarding the influence of the home physical environment on the sedentary behaviour and physical activity of children aged 8-14 years. A literature search of peer reviewed articles published between 2005 and 2011 resulted in 38 observational studies (21 with activity outcomes, 23 with sedentary outcomes) and 11 experimental studies included in the review. The most commonly investigated behavioural outcomes were television watching and moderate to vigorous physical activity. Media equipment in the home and to a lesser extent the bedroom were positively associated with children's sedentary behaviour. Physical activity equipment and the house and yard were not associated with physical activity, although environmental measures were exclusively self-reported. On the other hand, physical activity equipment was inversely associated with sedentary behaviours in half of studies. Observational studies that investigated the influence of the physical and social environment within the home space, found that the social environment, particularly the role of parents, was important. Experimental studies that changed the home physical environment by introducing a television limiting device successfully decreased television viewing, whereas the influence of introducing an active video game on activity outcomes was inconsistent. Results highlight that the home environment is an important influence on children's sedentary behaviour and physical activity, about which much is still unknown. While changing or controlling the home physical environment shows promise for reducing screen based sedentary behaviour, further interventions are needed to understand the broader impact of these changes. Future studies should prioritise investigating the influence of the home

  19. Taking Turns

    ERIC Educational Resources Information Center

    Hopkins, Brian

    2010-01-01

    Two people take turns selecting from an even number of items. Their relative preferences over the items can be described as a permutation, then tools from algebraic combinatorics can be used to answer various questions. We describe each person's optimal selection strategies including how each could make use of knowing the other's preferences. We…

  20. Decreasing Ventromedial Prefrontal Cortex Activity During Sequential Risk-Taking: An fMRI Investigation of the Balloon Analog Risk Task

    PubMed Central

    Schonberg, Tom; Fox, Craig R.; Mumford, Jeanette A.; Congdon, Eliza; Trepel, Christopher; Poldrack, Russell A.

    2012-01-01

    Functional imaging studies examining the neural correlates of risk have mainly relied on paradigms involving exposure to simple chance gambles and an economic definition of risk as variance in the probability distribution over possible outcomes. However, there is little evidence that choices made during gambling tasks predict naturalistic risk-taking behaviors such as drug use, extreme sports, or even equity investing. To better understand the neural basis of naturalistic risk-taking, we scanned participants using fMRI while they completed the Balloon Analog Risk Task, an experimental measure that includes an active decision/choice component and that has been found to correlate with a number of naturalistic risk-taking behaviors. In the task, as in many naturalistic settings, escalating risk-taking occurs under uncertainty and might be experienced either as the accumulation of greater potential rewards, or as exposure to increasing possible losses (and decreasing expected value). We found that areas previously linked to risk and risk-taking (bilateral anterior insula, anterior cingulate cortex, and right dorsolateral prefrontal cortex) were activated as participants continued to inflate balloons. Interestingly, we found that ventromedial prefrontal cortex (vmPFC) activity decreased as participants further expanded balloons. In light of previous findings implicating the vmPFC in value calculation, this result suggests that escalating risk-taking in the task might be perceived as exposure to increasing possible losses (and decreasing expected value) rather than the increasing potential total reward relative to the starting point of the trial. A better understanding of how neural activity changes with risk-taking behavior in the task offers insight into the potential neural mechanisms driving naturalistic risk-taking. PMID:22675289

  1. Evaluation of Work Place Group and Internet Based Physical Activity Interventions on Psychological Variables Associated with Exercise Behavior Change

    PubMed Central

    Dawson, Kimberley A.; Tracey, Jill; Berry, Tanya

    2008-01-01

    The purpose of this research was to compare group-based and internet-based physical activity interventions in terms of desirability, participant characteristics, exercise self-efficacy, and barrier self-efficacy. Pretest questionnaires were completed prior to voluntary enrollment into either of the ten-week physical activity interventions. Both interventions were based on Social Cognitive Theory and the Transtheoretical Model. Interventions were followed with posttest questionnaires. Results demonstrated that the internet intervention attracted more participants, but only the group-based participants showed significant increases in exercise and barrier self-efficacy. At pretest, participants who selected the internet intervention were significantly lower in life and job satisfaction than those who selected the group intervention. Results suggest that traditional group-based exercise interventions are helpful for improving cognitions associated with exercise behavior change (e.g., exercise self-efficacy) and that the internet intervention may help employees who fall into an “unhappy employee ”typology. Key pointsGroup-based physical activity interventions are capable of improving exercise self-efficacy and barrier self-efficacy.At pretest, participants who selected the internet physical activity intervention were significantly lower in job and life satisfaction than those who selected the group-intervention.While the internet intervention attracted more participants, the group-based physical activity intervention was more successful at changing cognitions associated with successful exercise behavior change. PMID:24149963

  2. Dizocilpine (MK-801) impairs learning in the active place avoidance task but has no effect on the performance during task/context alternation.

    PubMed

    Vojtechova, Iveta; Petrasek, Tomas; Hatalova, Hana; Pistikova, Adela; Vales, Karel; Stuchlik, Ales

    2016-05-15

    The prevention of engram interference, pattern separation, flexibility, cognitive coordination and spatial navigation are usually studied separately at the behavioral level. Impairment in executive functions is often observed in patients suffering from schizophrenia. We have designed a protocol for assessing these functions all together as behavioral separation. This protocol is based on alternated or sequential training in two tasks testing different hippocampal functions (the Morris water maze and active place avoidance), and alternated or sequential training in two similar environments of the active place avoidance task. In Experiment 1, we tested, in adult rats, whether the performance in two different spatial tasks was affected by their order in sequential learning, or by their day-to-day alternation. In Experiment 2, rats learned to solve the active place avoidance task in two environments either alternately or sequentially. We found that rats are able to acquire both tasks and to discriminate both similar contexts without obvious problems regardless of the order or the alternation. We used two groups of rats, controls and a rat model of psychosis induced by a subchronic intraperitoneal application of 0.08mg/kg of dizocilpine (MK-801), a non-competitive antagonist of NMDA receptors. Dizocilpine had no selective effect on parallel/sequential learning of tasks/contexts. However, it caused hyperlocomotion and a significant deficit in learning in the active place avoidance task regardless of the task alternation. Cognitive coordination tested by this task is probably more sensitive to dizocilpine than spatial orientation because no hyperactivity or learning impairment was observed in the Morris water maze. PMID:26970577

  3. The Place of Sport and Physical Activity in Young People's Lives and Its Implications for Health: Some Sociological Comments

    ERIC Educational Resources Information Center

    Smith, Andrew; Green, Ken

    2005-01-01

    This exploratory paper seeks, first, to offer some critical sociological comments on the common-sense, or rather ideological, claims surrounding two supposedly emerging "crises": namely, the alleged poor health and declining sport and physical activity participation levels of young people. In this regard, it is suggested that while young people…

  4. A Perfect Substorm: ICME-driven Magnetic Activity Catches Galaxy 15 in the Wrong Place at the Wrong Time

    NASA Astrophysics Data System (ADS)

    Connors, M. G.; Russell, C. T.; Angelopoulos, V.; Singer, H. J.; Glassmeier, K.

    2010-12-01

    At approximately 0825 UT on April 5, 2010, an ICME-driven shock encountered Earth's magnetosphere. The IMF, slightly southward since 0805 UT, turned more so, to an average value close to -15 nT, which was maintained for nearly an hour under high dynamic pressure conditions. Following a substorm growth phase, dipolarizations were observed at 0847 and 0903 UT by GOES West (11) in the midnight sector, at 0903 UT by three THEMIS spacecraft near X=-11, Y=-2 RE, and at about 0900 by GOES 14 near 2 MLT. Electron injections began at 0903 UT at the THEMIS spacecraft, while GOES 11 detected an increase in flux of energetic protons. A major dipolarization event at 0909 UT was observed at all of these spacecraft, and transferred magnetic flux from the vicinity of THEMIS to the inner magnetosphere, resulting in "overdipolarization" in the midnight sector. Extreme currents, more than 3 MA crossing the midnight sector, are inferred from ground magnetic perturbations of over 2000 nT, indicating this was an unusually strong substorm. Flux transfer associated with large electric fields observed at THEMIS (EY of 80 mV/m) is consistent with this increase in inner magnetospheric magnetic field. A second increase in ca. 1 MeV proton flux at this time led to a factor of over 10000 overall increase of this flux in the event. When the effects of this substorm reached synchronous orbit, the Galaxy 15 satellite was in eclipse when photoemission is not available to counter charging by the potentially high fluxes of energetic magnetospheric electrons that can occur during substorms. Galaxy 15 experienced a severe operational anomaly shortly after leaving eclipse and appears to have simply been at the wrong place at the wrong time when the “perfect” substorm occurred.

  5. Brazilian physicists take centre stage

    NASA Astrophysics Data System (ADS)

    Curtis, Susan

    2014-06-01

    With the FIFA World Cup taking place in Brazil this month, Susan Curtis travels to South America's richest nation to find out how its physicists are exploiting recent big increases in science funding.

  6. Peep show establishments, police activity, public place, and time: a study of secondary effects in San Diego, California.

    PubMed

    Linz, Daniel; Paul, Bryant; Yao, Mike

    2006-05-01

    An empirical study was undertaken in San Diego, California, to test assumptions made by the government and by conservative religious policy advocates that there is a greater incidence of crime in the vicinity of peep show establishments. We asked two questions: (a) Is criminal activity in San Diego particularly acute at peep show establishments compared to surrounding control locations? and (b) Is criminal activity in San Diego disproportionately greater at or near peep show establishments between the hours of 2 a.m. and 6 a.m. compared to other times of the day? The levels of crime activity and the expenditure of police resources were examined by measuring the number of calls-for-service (CFSs) to the police within a 1,000-ft. area on either side of the peep show establishments and comparably-sized control areas beyond the immediate 1,000-foot area. A more focused late-night (2 a.m. to 6 a.m.) analysis was also undertaken. The results showed no reliable evidence of differences in crime levels between the control and test areas, nor was there any evidence of disproportionately greater amounts of crime within the 2 a.m. to 6 a.m. time period in the areas surrounding the peep show establishments. We concluded that San Diego does not have a problem with crime at the peep show establishments generally, nor is there a heightened problem with crime during the 2 a.m. to 6 a.m. period. We discuss the implications of assuming that peep show establishments are associated with negative effects in the community and the possibility of viewpoint discrimination against sex communication. PMID:16817065

  7. 75 FR 64276 - Takes of Marine Mammals Incidental to Specified Activities; Navy Training Conducted at the Silver...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-19

    ... produces impact sound (i.e., pile driving) results in potential take of marine mammals by harassment (70 FR 1871). Current NMFS criteria (70 FR 1871) regarding exposure of marine mammals to underwater sounds is... Washington (Puget Sound) and British Columbia (Lowry et al. 1992). They remain there until spring...

  8. 78 FR 33811 - Takes of Marine Mammals Incidental to Specified Activities; Low-Energy Marine Geophysical Survey...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-05

    ...NMFS has received an application from the Scripps Institution of Oceanography (SIO), a part of the University of California at San Diego, for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to conducting a low-energy marine geophysical (seismic) survey in the tropical western Pacific Ocean, September to October 2013. Pursuant to the Marine Mammal......

  9. 77 FR 43238 - Takes of Marine Mammals Incidental to Specified Activities; Navy Training Conducted at the Silver...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-24

    ...In accordance with provisions of the Marine Mammal Protection Act (MMPA) as amended, notification is hereby given that an Incidental Harassment Authorization (IHA) has been issued to the U.S. Navy (Navy) to take marine mammals, by harassment, incidental to conducting training exercises at the Silver Strand Training Complex (SSTC) in the vicinity of San Diego Bay,...

  10. 78 FR 2371 - Taking of Marine Mammals Incidental to Specified Activities; Construction of the East Span of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ...In accordance with provisions of the Marine Mammal Protection Act (MMPA) as amended, notification is hereby given that an Incidental Harassment Authorization (IHA) has been issued to the California Department of Transportation (CALTRANS) to take small numbers of California sea lions, Pacific harbor seals, harbor porpoises, and gray whales, by harassment, incidental to construction of a......

  11. 78 FR 49729 - Takes of Marine Mammals Incidental to Specified Activities; U.S. Air Force Launches, Aircraft and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-15

    ... has received a request from the U.S. Air Force (USAF) for authorization to take marine mammals... (MMPA), NMFS is announcing our receipt of the USAF's request for the development and implementation of... comments on the USAF's application and request. DATES: Comments and information must be received no...

  12. 77 FR 20361 - Takes of Marine Mammals Incidental to Specified Activities; Pier 36/Brannan Street Wharf Project...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-04

    ...In accordance with the Marine Mammal Protection Act (MMPA) implementing regulations, notification is hereby given that NMFS has issued an Incidental Harassment Authorization (IHA) to the Port of San Francisco (Port), allowing the take of small numbers of marine mammals, by Level B harassment only, incidental to pile driving during construction of the Brannan Street...

  13. 77 FR 39471 - Small Takes of Marine Mammals Incidental to Specified Activities; Pile Driving in Port Townsend...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ...NMFS has received a complete and adequate application from the Washington State Department of Transportation/Ferries Division (WSF) for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to pile driving during replacement of the Port Townsend Ferry Terminal Transfer Span. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS proposes to issue an......

  14. The Effect of Recreational Activities on the Elimination of State-Trait Anxiety of the Students Who Will Take the SBS Placement Test

    ERIC Educational Resources Information Center

    Birtürk, Atilay; Karagün, Elif

    2015-01-01

    The purpose of this study is to examine whether recreational activities have an effect on the elimination of state-trait anxiety of the students who will take the "SBS Placement Test" which is an exam for transition from secondary school to high school. For this purpose, as well as an information survey which determined the…

  15. Do nuclear reactions take place under chemical stimulation?

    SciTech Connect

    Bockris, J.O.; Lin, G.H.; Bush, R.T.

    1996-09-01

    Several examples of nuclear reactions occurring under the stimulation of chemical type energies are given. The production of tritium from deuterium in Pd has more than 100 published confirmations. Three models suggest circumstances such that barriers between nucleii may become transparent. 24 refs.

  16. Using Personalized Education to Take the Place of Standardized Education

    ERIC Educational Resources Information Center

    Gao, Pengyu

    2014-01-01

    Economic model has been greatly shifted from labor demanding to innovation demanding, which requires education system has to produce creative people. This paper illustrates how traditional education model accrued and developed based on satisfying the old economic model for labor demanding but did not meet the new social requirement for innovation…

  17. America's Aging Farmers: Who Will Take Their Place?

    ERIC Educational Resources Information Center

    Gale, Fred

    1993-01-01

    Trends over the last decade show an increase in the average age of farmers and a steady decline in the number of young people entering farming. These trends will have adverse effects on rural economies and communities. It is unlikely that current government programs can reverse trends toward large corporate farms. (KS)

  18. 78 FR 11821 - Takes of Marine Mammals Incidental to Specified Activities; Low-Energy Marine Geophysical Survey...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-20

    ...NMFS has received an application from the U.S. Geological Survey (USGS), for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment, incidental to conducting a low-energy marine geophysical (seismic) survey in the Gulf of Mexico, April to May, 2013. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on its proposal to issue an IHA to......

  19. Practical Considerations when Using Pedometers to Assess Physical Activity in Population Studies: Lessons from the Burnie Take Heart Study

    ERIC Educational Resources Information Center

    Schmidt, Michael D.; Blizzard, C. Leigh; Venn, Alison J.; Cochrane, Jennifer A.; Dwyer, Terence

    2007-01-01

    The aim of this study was to summarize both practical and methodological issues in using pedometers to assess physical activity in a large epidemiologic study. As part of a population-based survey of cardiovascular disease risk factors, physical activity was assessed using pedometers and activity diaries in 775 men and women ages 25-64 years who…

  20. "Numbers, Numerals, Numeration": Activities Using Numeration Cards with Emphasis on Place Value, 100 Board Activities, and Number Words. (Grades 1-4.) Title I Elementary Mathematics Program.

    ERIC Educational Resources Information Center

    Oxberger, Nancy; Sollenbarger, Sherry

    Mathematics activities and materials for teaching and reinforcing number concepts are presented. The activities, which rely primarily on number cards, are divided into the following sections: (1) sets less than ten; (2) the teen numbers; (3) sets and numerals to 100; (4) numeration; and (5) words that represent numbers (e.g., "one=1"). An…

  1. Physical Activity on Medical Prescription: A Qualitative Study of Factors Influencing Take-Up and Adherence in Chronically Ill Patients

    ERIC Educational Resources Information Center

    Gasparini, William; Knobé, Sandrine; Didierjean, Romaine

    2015-01-01

    Objective: This study sought to determine the effects of an innovative public health programme offering physical and sports activities on medical prescription to chronically ill patients. Method: Semi-structured interviews were conducted with programme participants at two time points: at the start of their activity (n?=?33) and 3?months after the…

  2. Taking Part Counts: Adolescents' Experiences of the Transition from Inactivity to Active Participation in School-Based Physical Education

    ERIC Educational Resources Information Center

    Brooks, Fiona; Magnusson, Josefine

    2006-01-01

    Identifying ways to increase and sustain active living among young people represents a priority for health promotion interventions. This qualitative study explored the experiences of adolescent boys and girls in the United Kingdom (aged 14-15 years) who had made the transition from inactivity to active participation in physical education (PE). The…

  3. 77 FR 60679 - Takes of Marine Mammals Incidental to Specified Activities; U.S. Navy Training and Testing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-04

    ... Environmental Impact Statement (DEIS) for AFTT was made available to the public on May 11, 2012 (77 FR 27742... Specified Activities; U.S. Navy Training and Testing Activities in the Atlantic Fleet Training and Testing... Fleet Training and Testing (AFTT) study area from January 2014 through January 2019. Pursuant to...

  4. 77 FR 60678 - Takes of Marine Mammals Incidental to Specified Activities; U.S. Navy Training and Testing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-04

    ... Environmental Impact Statement (DEIS) for HSTT was made available to the public on May 11, 2012 (77 FR 27743...) analyzing the effects on the human environment of implementing their preferred alternative (among others... Specified Activities; U.S. Navy Training and Testing Activities in the Hawaii-Southern California...

  5. [Risk-taking behaviors among young people].

    PubMed

    Le Breton, David

    2004-01-01

    Risk-taking behaviors are often an ambivalent way of calling for help from close friends or family - those who count. It is an ultimate means of finding meaning and a system of values; it is a sign of an adolescent's active resistance and attempts to re-establish his or her place in the world. It contrasts with the far more incisive risk of depression and the radical collapse of meaning. In spite of the suffering it engenders, risk-taking nevertheless has a positive side, fostering independence in adolescents and a search for reference points. It leads to a better self-image and is a means of developing one's identity. It is nonetheless painful in terms of its repercussions in terms of injuries, death or addiction. The turbulence caused by risk-taking behaviors illustrates a determination to be rid of one's suffering and to fight on so that life can, at last, be lived. PMID:15918660

  6. Finding a Place.

    ERIC Educational Resources Information Center

    Giorgis, Cyndi; Johnson, Nancy J.

    2001-01-01

    Presents annotations of 31 works of children's literature addressing feeling a sense of place, discovering a place, creating a place, noting how places present obstacles, and setting out for new places. Lists 7 books about Jazz with related Web sites and lists 7 other books that address familial relationships. (SG)

  7. Two regulatory elements of similar structure and placed in tandem account for the repressive activity of the first intron of the human apolipoprotein A-II gene.

    PubMed Central

    Bossu, J P; Chartier, F L; Fruchart, J C; Auwerx, J; Staels, B; Laine, B

    1996-01-01

    Recent reports indicate that apolipoprotein (apo) A-II, the second most abundant protein of high-density lipoproteins, plays a crucial role in counteracting the beneficial effect of apo A-I against atherogenesis. Transcription of the human apo A-II gene is controlled by an enhancer comprising 14 regulatory elements located upstream of its promoter whereas the first intron of this gene behaves as a silencer. Here we show that two sequence elements account for the repressive activity of this intron and correspond to negative regulatory elements termed NRE I and NRE II. The activity of intron I and the nuclear proteins binding to NRE I and II are encountered in hepatic cells but not in non-hepatic cells studied here. Both NREs form nucleoprotein complexes of very similar physicochemical characteristics and bind the same or closely related proteins. Site-directed mutagenesis, transient transfection and gel-shift analysis experiments indicate that both NREs exhibit similar structures, being composed of two sites required for maximal activity and optimal binding of transcription factors. Therefore two negative regulatory elements of similar structure and function, placed in tandem, account for the repressive activity of the first intron of the human apo A-II gene. These NREs do not exhibit structural similarity with known NREs of other genes. PMID:8809045

  8. Physical activity among Norwegian adolescents- a multilevel analysis of how place of residence is associated with health behaviour: the Young-HUNT study

    PubMed Central

    2013-01-01

    Introduction The purpose of this article is to investigate whether and to what degree participation in physical activity among adolescents is associated with area economic deprivation in the municipality where they live. In the study we took account of aggregated informal social capital at the municipality level and compositional effects due to spatial concentration of individual variables known to be associated with physical activity. These include informal social participation, participation in other cultural activities, and family affluence. Methods The study was based on a secondary analysis of data from the Norwegian HUNT study and municipality characteristics from the Norwegian Social Science Data Service ‘Commune Database’ from 2006. The sample consisted of 8114 adolescents whose ages ranged from 13 to 19. The explanatory power of the independent variables on the dependent variable was assessed using a multilevel analysis in which individuals comprised the first level and were nested within the municipality level. Results The average level of physical activity was not negatively associated with the level of area economic deprivation when we adjusted for informal social participation at the community level. Adjusting for area economic deprivation, we found that informal social participation at the community level was associated with a higher level of participation in physical activity at p< .01. Conclusion For adolescents in a given municipality, informal social participation is more strongly associated with a higher level of physical activity than the degree of area economic deprivation. This finding supports our social capital hypothesis, which states that the amount of social capital is strengthening the individual’s ability to take part in physical activity. PMID:23883144

  9. Approach to theoretical estimation of the activation energy of particle aggregation taking ionic nonclassic polarization into account

    NASA Astrophysics Data System (ADS)

    Li, Qinyi; Tang, Ying; He, Xinhua; Li, Hang

    2015-10-01

    The activation energy of particle aggregation in suspensions is a very important kinetic parameter in a wide range of science and engineering applications. At present, however, there is no theory that can theoretically predict the activation energy. Because the activation energy is often less than 10 kT (where k is the Boltzmann constant and T is the temperature), it is difficult to experimentally measure. In this study, a theory for calculating the activation energy is established. Experimental measurements of the activation energy of montmorillonite aggregation were performed with different electrolyte and particle concentrations using the dynamic light scattering (DLS) technique. The validity of the theory was verified by the experiments. This study confirmed that both the method for activation energy measurements by DLS and the theory for its calculation can be applied to suspensions of polydisperse nonspherical particles. The average kinetic energy at the moment of particle collision in the aggregation process was found to be 0.2 kT, which is less than the instantaneous kinetic energy of a Brownian particle (0.5 kT) because of the viscous resistance of the water medium. This study also shows that adsorbed Na+ is strongly polarized in the electric field near the particle surface, and the polarization increases the effective charge of Na+ from +1 to +1.18.

  10. Places for Pedagogies, Pedagogies for Places

    ERIC Educational Resources Information Center

    Duhn, Iris

    2012-01-01

    Working with an understanding of assemblage as the ad hoc groupings of vibrant materials and elements, this article argues that conceptualizing place as an assemblage opens possibilities for bridging the gap between subjects and objects that continue to structure pedagogy. Considering "place" as an assemblage of humans and their multiple "others"…

  11. Discussion of impact of relics activation on protection and utilization approaches-take the old summer palace as an example

    NASA Astrophysics Data System (ADS)

    Xiaoqi, J.

    2015-08-01

    As the popularization of cultural relics and the rapid development of cultural tourism industry, a large number of cultural relic tourism resources goes into public eyes. Activation of relics has became an important way for tourist to contact and understand culture relics. The way of how to properly interpret the historical sense and cultural uniqueness to the masses of tourists in order to achieve social service functions of relic resources has always been research focal point of site protection and utilization, so nowadays it has important significance to protection and utilization of heritage resources in our country. From the point of activation of relics and based on the analysis of resource characteristic, the paper in depth discuss ways of activation of relics of the Old Summer Palace, in order to provide reference for sustainable development of sites tourism in China.

  12. Frequency and rates of outdoor activities, and perceptions of places to perform these activities by Native Americans and Caucasians interviewed in Tennessee.

    PubMed

    Burger, Joanna; Gochfeld, Michael; Jeitner, Christian; Pittfield, Taryn; Marchioni, Meredith

    2012-12-01

    Activity patterns and perceptions play a key role in human health risk, management, and planning. A sample of 233 people attending a Native American festival in Cookeville, Tennessee was interviewed to determine the types, percent participation, and outdoor activities rates, and their perceptions of the importance of characteristics of nuclear sites. Results indicate that: (1) a high percentage of respondents used outdoor environments, (2) they used them for consumptive (hunting, fishing), non-consumptive (hiking, walking, bird-watching), and religious/sacred activities, (3) a higher percentage of respondents engaged in non-consumptive than consumptive activities, (4) praying or meditating, communing with nature, and bird-watching had the highest uses rates (5) the environmental characteristics rated the highest were lack of radionuclides that presented a health risk, no visible smog, clean air, and unpolluted water, (6) the presence of people, buildings and roads were rated the lowest, and (7) Native Americans had higher outdoor participation rates, participated more frequently, and evaluated environmental characteristics higher than did Caucasians. This information can be used by managers to create and maintain outdoor habitats that fit the needs of local people. Planning and management require information on public policy, human needs and requirements, and human perceptions and evaluations of environmental characteristics. PMID:23229153

  13. Frequency and rates of outdoor activities, and perceptions of places to perform these activities by Native Americans and Caucasians interviewed in Tennessee

    PubMed Central

    Gochfeld, Michael; Jeitner, Christian; Pittfield, Taryn

    2015-01-01

    Activity patterns and perceptions play a key role in human health risk, management, and planning. A survey of 233 people attending a Native American festival in Cookeville Tennessee were interviewed to determine the types, percent participation, and outdoor activities rates, and their perceptions of the importance of characteristics of sites. The indicate that: 1) a high percentage of respondents used outdoor environments, 2) they used them for consumptive (hunting, fishing), non-consumptive (hiking, walking, bird-watching), and religious/sacred activities, 3) a higher percentage of respondents engaged in non-consumptive than consumptive activities, 4) praying or meditating, communing with nature, and bird-watching had the highest uses rates 5) the environmental characteristics rated the highest were lack of radionuclides that presented a health risk, no visible smog, clean air, and unpolluted water, 6) presence of people, buildings and roads were rated the lowest and 7) Native Americans had higher participation rates, participated more frequently, and evaluated environmental characteristics higher than did Caucasians. This information can be used by managers to create and maintain outdoor habitats that fit the needs of local people. Planning and management require information on public policy, human needs and requirements, and human perceptions and evaluations of environmental characteristics. PMID:23229153

  14. 77 FR 27189 - Takes of Marine Mammals Incidental to Specified Activities; Low-Energy Marine Geophysical Survey...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-09

    ... March 13, 2012, NMFS published a notice in the Federal Register (77 FR 14744) making preliminary... FR 14744, March 13, 2012). The activities to be conducted have not changed between the proposed IHA... proposed IHA notice (77 FR 14744, March 13, 2012), the IHA application, EA, and associated ]...

  15. 78 FR 6977 - Takes of Marine Mammals Incidental to Specified Activities; U.S. Navy Training and Testing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-31

    ... HSTT was made available to the public on May 11, 2012 (77 FR 27743) and may also be viewed at http.... During sea trials, each new ship propulsion engine is operated at full power and subjected to high-speed..., lengths, and speeds used in both training and testing activities are shown in Table 8. While these...

  16. 78 FR 7049 - Takes of Marine Mammals Incidental to Specified Activities; U.S. Navy Training and Testing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-31

    ... May 11, 2012 (77 FR 27742). Documents cited in this notice may also be viewed, by appointment, during... ship propulsion engine is operated at full power and subjected to high-speed runs and steering tests... military readiness activities. Marine mammals present in the Study Area may be exposed to sound from...

  17. 78 FR 19224 - Taking of Marine Mammals Incidental to Specified Activities; U.S. Marine Corps Training Exercises...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-29

    ... FR 28370). In summary, sound exposure may result in physiological impacts, stress responses, and... of the same activities from 2010 to 2012 (75 FR 72807, November 26, 2010; 77 FR January 3, 2012... support craft is to remotely control High Speed Maneuvering Surface Targets (HSMSTs) or to...

  18. 78 FR 57354 - Takes of Marine Mammals Incidental to Specified Activities; Low-Energy Marine Geophysical Survey...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-18

    ... June 5, 2013, NMFS published a notice in the Federal Register (78 FR 33811) making preliminary... program in a previous notice for the proposed IHA (78 FR 33811, June 5, 2013). The activities to be... source specifications, the reader should refer to the notice of the proposed IHA (78 FR 33811, June...

  19. 78 FR 73009 - Takes of Marine Mammals Incidental to Specified Activities; U.S. Navy Training and Testing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-04

    ... opportunity for review and comment via the proposed rule for this action published on January 31, 2013 (78 FR... appropriate. Description of Specified Activities The proposed rule (78 FR 7050, January 31, 2013) and AFTT... rule (78 FR 7050, January 31, 2013; page 7066) and AFTT FEIS/OEIS ( http://www.aftteis.com ). For...

  20. 77 FR 19231 - Takes of Marine Mammals Incidental to Specified Activities; Navy Training Conducted at the Silver...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-30

    ..., NMFS published a Federal Register notice (75 FR 64276) requesting comments from the public concerning... training activities at the SSTC is provided in the Federal Register notice for the proposed IHA (75 FR... training from the original proposed IHA (75 FR 64276; October 19, 2010), therefore, it is not repeated...

  1. 75 FR 5055 - Taking and Importing Marine Mammals; U.S. Navy's Atlantic Fleet Active Sonar Training (AFAST)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-01

    ... to AFAST training, maintenance, and RDT&E became effective on January 22, 2009 (74 FR 4843, January... conducted within the AFAST Study Area under regulations issued on January 22, 2009 (74 FR 4843, January 27.... Navy's Atlantic Fleet Active Sonar Training (AFAST) AGENCY: National Marine Fisheries Service...

  2. 77 FR 32943 - Takes of Marine Mammals Incidental to Specified Activities; Pile Driving in the Columbia River, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-04

    .... A pneumatic underwater chainsaw may be used if a pile breaks in the process, but associated noise is... notice in the Federal Register on August 19, 2011 (76 FR 51947), requesting comments from the public on... activity may be found in NMFS' proposed IHA document in the Federal Register (76 FR 51947, August 19,...

  3. 78 FR 58524 - Takes of Marine Mammals Incidental to Specified Activities; U.S. Navy Training and Testing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-24

    ... Islands Training and Testing (MITT) Study Area from July 2015 through July 2020. Pursuant to the Marine... Navy is requesting a 5-year LOA for training and testing activities to be conducted from 2015 through...; Naval Sea Systems Command (NAVSEA) testing; and Office of Naval Research (ONR) and Naval...

  4. Legends for Sale, Poems for Free: Whole Language Activities Can Be Inspired by Risk-Taking and Scene Changes.

    ERIC Educational Resources Information Center

    Kaminski, Robert

    1991-01-01

    Describes two classroom activities that were developed to promote a whole language approach to listening, speaking, reading, and writing. One involved fifth grade students who wrote legends that other students paid to read and evaluate, and the other involved an eighth grade English class who gave free poetry readings in a coffee house setting.…

  5. Keep Taking the Tablets? Assessing the Use of Tablet Devices in Learning and Teaching Activities in the Further Education Sector

    ERIC Educational Resources Information Center

    Fabian, Khristin; MacLean, Donald

    2014-01-01

    This article summarises the methodology and outcomes of an interventionist/action research project to assess the benefits, and potential pitfalls, of the use of mobile devices in learning and teaching activities in a Further Education environment. A bank of 15 tablet devices were purchased and prepared for classroom use. Staff members were…

  6. 75 FR 54599 - Takes of Marine Mammals Incidental to Specified Activities; Construction of the Knik Arm Crossing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-08

    ... Specified Activities; Construction of the Knik Arm Crossing, Alaska AGENCY: National Marine Fisheries... received a request from the Knik Arm Bridge Toll Authority (KABATA), in coordination with the Department of... construction of a bridge across Knik Arm, named the Knik Arm Crossing, Alaska, over the course of...

  7. 76 FR 68720 - Takes of Marine Mammals Incidental to Specified Activities; Low-Energy Marine Geophysical Survey...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-07

    ... proposed IHA for the SIO seismic survey was published in the Federal Register on July 29, 2011 (76 FR 45518... published a notice in the Federal Register (76 FR 45518) making preliminary determinations and proposing to... previous notice for the proposed IHA (76 FR 45518, July 29, 2011). The activities to be conducted have...

  8. 78 FR 78105 - Takes of Marine Mammals Incidental to Specified Activities; U.S. Navy Training and Testing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... (78 FR 6978). Further, more generally, NMFS is committed to the use of the best available science... Activities The proposed rule (78 FR 6978, January 31, 2013) and HSTT FEIS/OEIS include a complete description... proposed rule and HSTT FEIS/OEIS (78 FR 6978, January 31, 2013; pages 6987-6988;...

  9. Take Pride in America.

    ERIC Educational Resources Information Center

    Indiana State Dept. of Education, Indianapolis. Center for School Improvement and Performance.

    During the 1987-88 school year the Indiana Department of Education assisted the United States Department of the Interior and the Indiana Department of Natural Resources with a program which asked students to become involved in activities to maintain and manage public lands. The 1987 Take Pride in America (TPIA) school program encouraged volunteer…

  10. Activation of p38 signaling in the microglia in the nucleus accumbens contributes to the acquisition and maintenance of morphine-induced conditioned place preference.

    PubMed

    Zhang, Xue-Qin; Cui, Yu; Cui, Yue; Chen, Yu; Na, Xiao-Dong; Chen, Feng-Ying; Wei, Xu-Hong; Li, Yong-Yong; Liu, Xian-Guo; Xin, Wen-Jun

    2012-02-01

    Several lines of evidence have suggested that activated glia contributes to morphine-induced reward (conditioned place preference, CPP). Compared to well-defined roles of astrocyte in morphine CPP, the role of microglia in the nucleus accumbens (NAc) remains poorly characterized. The aim of the present study was to investigate the distinct role of microglia in morphine-induced CPP. Systemic administration of morphine (7.5 mg/kg for 5 days) induced significant preference for the morphine-paired compartment in rats, which lasted for at least 6 days after cessation of morphine treatment. Immunohistochemistry results showed that activation of p38 in the NAc microglia induced by chronic morphine treatment maintained on day 11. Bilateral intra-NAc injection of minocycline, a putative microglia inhibitor, or SB203580, an inhibitor of p38, prior to morphine administration not only inhibited p38 activation in the microglia but impaired the acquisition of CPP. On the day following the acquisition of morphine CPP, a single injection of minocycline or SB203580 failed to block the expression of CPP. Notably, pretreatment with minocycline or SB203580 for 5 days following the acquisition of morphine CPP significantly suppressed the activation of p38 and attenuated the maintenance of morphine CPP. Collectively, our present study indicates that the p38 signaling in the NAc microglia may play an important role in the acquisition and maintenance but not the expression of morphine CPP, and provides new evidence that microglia might be a potential target for the therapy of morphine addiction. PMID:22004988

  11. Taking inquiry to the next level: Tablet PC's to stimulate active learning and unify introductory physics curriculum

    NASA Astrophysics Data System (ADS)

    Bykov, Tikhon; Kosheleva, Yelena

    2009-03-01

    A project has been started in 2005 to design innovative curriculum for the intro physics courses at McMurry University. The project is rooted in science education research and ideas from the NFW. The goal is to achieve better integration of traditional course components by means of instructional design and technology. First, a system of flexible curriculum modules with emphasis on inquiry-based teaching has been introduced. Second, technology is used to improve continuity among module components (lecture/lab/discussion) and stimulate active learning. Enabling technology suite incorporates Tablet PC's and software applications including java-based Physlets, tablet-adapted personal response systems, and PASCO data acquisition systems. Lab curriculum has been modified to accommodate for different learning styles, and levels of baseline knowledge. Activity options and pre-lab Physlet-based assignments were added. To enhance knowledge generalization, multiple experiments are used to illustrate different aspects of the same physics phenomenon. Physlet-based problems were adapted for student peer group discussions. Student feedback showed that modifications were beneficial. Student knowledge assessment, performed with the FCI test, indicated improvement in student learning.

  12. Temporal and spatial strategies in an active place avoidance task on Carousel: a study of effects of stability of arena rotation speed in rats

    PubMed Central

    Stuchlík, Aleš

    2015-01-01

    The active place avoidance task is a dry-arena task used to assess spatial navigation and memory in rodents. In this task, a subject is put on a rotating circular arena and avoids an invisible sector that is stable in relation to the room. Rotation of the arena means that the subject’s avoidance must be active, otherwise the subject will be moved in the to-be-avoided sector by the rotation of the arena and a slight electric shock will be administered. The present experiment explored the effect of variable arena rotation speed on the ability to avoid the to-be-avoided sector. Subjects in a group with variable arena rotation speed learned to avoid the sector with the same speed and attained the same avoidance ability as rats in a group with a stable arena rotation speed. Only a slight difference in preferred position within the room was found between the two groups. No difference was found between the two groups in the dark phase, where subjects could not use orientation cues in the room. Only one rat was able to learn the avoidance of the to-be-avoided sector in this phase. The results of the experiment suggest that idiothetic orientation and interval timing are not crucial for learning avoidance of the to-be-avoided sector. However, idiothetic orientation might be sufficient for avoiding the sector in the dark. PMID:26417540

  13. Temporal and spatial strategies in an active place avoidance task on Carousel: a study of effects of stability of arena rotation speed in rats.

    PubMed

    Bahník, Štěpán; Stuchlík, Aleš

    2015-01-01

    The active place avoidance task is a dry-arena task used to assess spatial navigation and memory in rodents. In this task, a subject is put on a rotating circular arena and avoids an invisible sector that is stable in relation to the room. Rotation of the arena means that the subject's avoidance must be active, otherwise the subject will be moved in the to-be-avoided sector by the rotation of the arena and a slight electric shock will be administered. The present experiment explored the effect of variable arena rotation speed on the ability to avoid the to-be-avoided sector. Subjects in a group with variable arena rotation speed learned to avoid the sector with the same speed and attained the same avoidance ability as rats in a group with a stable arena rotation speed. Only a slight difference in preferred position within the room was found between the two groups. No difference was found between the two groups in the dark phase, where subjects could not use orientation cues in the room. Only one rat was able to learn the avoidance of the to-be-avoided sector in this phase. The results of the experiment suggest that idiothetic orientation and interval timing are not crucial for learning avoidance of the to-be-avoided sector. However, idiothetic orientation might be sufficient for avoiding the sector in the dark. PMID:26417540

  14. Taking centre stage...

    NASA Astrophysics Data System (ADS)

    1998-11-01

    HAMLET (Highly Automated Multimedia Light Enhanced Theatre) was the star performance at the recent finals of the `Young Engineer for Britain' competition, held at the Commonwealth Institute in London. This state-of-the-art computer-controlled theatre lighting system won the title `Young Engineers for Britain 1998' for David Kelnar, Jonathan Scott, Ramsay Waller and John Wyllie (all aged 16) from Merchiston Castle School, Edinburgh. HAMLET replaces conventional manually-operated controls with a special computer program, and should find use in the thousands of small theatres, schools and amateur drama productions that operate with limited resources and without specialist expertise. The four students received a £2500 prize between them, along with £2500 for their school, and in addition they were invited to spend a special day with the Royal Engineers. A project designed to improve car locking systems enabled Ian Robinson of Durham University to take the `Working in industry award' worth £1000. He was also given the opportunity of a day at sea with the Royal Navy. Other prizewinners with their projects included: Jun Baba of Bloxham School, Banbury (a cardboard armchair which converts into a desk and chair); Kobika Sritharan and Gemma Hancock, Bancroft's School, Essex (a rain warning system for a washing line); and Alistair Clarke, Sam James and Ruth Jenkins, Bishop of Llandaff High School, Cardiff (a mechanism to open and close the retractable roof of the Millennium Stadium in Cardiff). The two principal national sponsors of the competition, which is organized by the Engineering Council, are Lloyd's Register and GEC. Industrial companies, professional engineering institutions and educational bodies also provided national and regional prizes and support. During this year's finals, various additional activities took place, allowing the students to surf the Internet and navigate individual engineering websites on a network of computers. They also visited the

  15. Immune polarization by hookworms: taking cues from T helper type 2, type 2 innate lymphoid cells and alternatively activated macrophages.

    PubMed

    Nair, Meera G; Herbert, De'Broski R

    2016-06-01

    Cellular and molecular investigation of parasitic helminth infections has greatly accelerated the understanding of type 2 immune responses. However, there remains considerable debate regarding the specific leucocytes that kill parasites and whether these mechanisms are distinct from those responsible for tissue repair. Herein, we chronicle discoveries over the past decade highlighting current paradigms in type 2 immunity with a particular emphasis upon how CD4(+) T helper type 2 cells, type 2 innate lymphoid cells and alternatively activated macrophages coordinately control helminth-induced parasitism. Primarily, this review will draw from studies of the murine nematode parasite Nippostrongylus brasiliensis, which bears important similarities to the human hookworms Ancylostoma duodenale and Necator americanus. Given that one or more hookworm species currently infect millions of individuals across the globe, we propose that vaccine and/or pharmaceutical-based cure strategies targeting these affected human populations should incorporate the conceptual advances outlined herein. PMID:26928141

  16. Re(Place) Your Typical Writing Assignment: An Argument for Place-Based Writing

    ERIC Educational Resources Information Center

    Jacobs, Elliot

    2011-01-01

    Place-based writing affords students an opportunity to write meaningfully about themselves, grounded in a place that they know. Place-based writing is versatile and can be additive--taking just a week or two within a semester of different projects--or transformative, if positioned as the theme for an entire course. If students can learn to write…

  17. Embodied Experiences of Place: A Study of History Learning with Mobile Technologies

    ERIC Educational Resources Information Center

    Price, S.; Jewitt, C.; Sakr, M.

    2016-01-01

    This paper reports an empirical study that takes a multimodal analytical approach to examine how mobile technologies shape students' exploration and experience of place during a history learning activity in situ. In history education, mobile technologies provide opportunities for authentic experiential learning activities that have the potential…

  18. How to Cope with Sheltering in Place

    MedlinePlus

    ... your own or a relative’s home, school, or work. Sheltering in place may be required because of an emergency such ... things to keep yourself calm while sheltering in place. Relax your body often by doing things that work for you—take deep breaths, stretch, meditate or ...

  19. Place and Pedagogy

    ERIC Educational Resources Information Center

    Orr, David

    2013-01-01

    David Orr's classic article links education to living in the outdoors and studying all disciplines through the unifying lens of place. Pedagogy of place counters abstraction, it is the natural world embodying principles of learning that involve direct observation, investigation, experimentation, and manual skills. Place is the laboratory providing…

  20. Teenagers and Risk-Taking at Camp.

    ERIC Educational Resources Information Center

    Woods, Ann

    2002-01-01

    Teen risk-taking is normal, healthy developmental behavior. Teens act out their fantasies--good and bad--at camp because it is a safe place away from parents. Signs of unhealthy risk-taking, camp staff responses, and how the September 11 tragedy might affect risk-taking are discussed. Sidebars describe tips for understanding adolescent behavior…

  1. Analytic Hierarchy Process to Define the Most Important Factors and Related Technologies for Empowering Elderly People in Taking an Active Role in their Health.

    PubMed

    Fico, G; Gaeta, E; Arredondo, M T; Pecchia, L

    2015-09-01

    Successful management of health conditions in older population is determined by strategic involvement of a professional team of careers and by empowering patients and their caregivers to take over a central role and responsibility in the daily management of condition. Identifying, structuring and ranking the most important needs related to these aspects could pave the way for improved strategies in designing systems and technological solutions supporting user empowerment. This paper presents the preliminary results of a study aiming to elicit these needs. Healthcare professionals, working together in the European and Innovation Partnership on Active and Healthy Ageing (EIP-AHA) initiative, have defined a set of needs and factors that have been organized in two hierarchies around the concepts of patient activation and proactive and prepared care team, defined in the Chronic Care Model. The two hierarchies have been mapped, by a team of experts in computer science, with technologies and solutions that could facilitate the achievement of the identified needs. PMID:26254254

  2. Participant report of therapist-delivered active ingredients in a telephone-delivered brief motivational intervention predicts taking steps towards change

    PubMed Central

    Lee, Christina S.; Longabaugh, Richard; Baird, Janette; Streszak, Val; Nirenberg, Ted; Mello, Michael

    2015-01-01

    Objective Given the widespread potential for disseminating Motivational Interviewing (MI) through technology, the question of whether MI active ingredients are present when not delivered in person is critical to assure high treatment quality. The Participant Rating Form (PRF) was developed and used to evaluate therapist-delivered active ingredients in phone-delivered MI with hazardous drinking Emergency Department patients. Method A factor analysis of all PRFs completed after receiving one call (n=256) was conducted. Multiple regression analysis was used to examine whether PRF factors predicted a measure of motivation to change -- taking steps—at the second call (n=214). Results The majority of participants were male (65%), with a mean age of 32 years and with an average alcohol ASSIST (Alcohol, Smoking, and Substance Involvement Screening Test) score of 20.5 (SD = 7.1). Results of the factor analysis for the PRF revealed Relational (working collaboration) and Technical (MI behaviors) factors. After controlling for demographics, alcohol severity, and baseline readiness, the technical factor predicted self-report of increased taking steps towards change while the relational factor did not explain any additional variance. Conclusions Our study adds to the growing literature investigating patient perspectives of therapist skill as a source of information to better understand MI active ingredients. The PRF is a feasible instrument for measuring the patient’s experience of phone-based MI. Results indicate that MI active ingredients of change (relational and technical components) were present in the telephone intervention as hypothesized. Clinical Trial Registration # 01326169. PMID:26441490

  3. Hurt but still alive: Residual activity in the parahippocampal cortex conditions the recognition of familiar places in a patient with topographic agnosia.

    PubMed

    van Assche, Mitsouko; Kebets, Valeria; Lopez, Ursula; Saj, Arnaud; Goldstein, Rachel; Bernasconi, Françoise; Vuilleumier, Patrik; Assal, Frédéric

    2016-01-01

    The parahippocampal cortex (PHC) participates in both perception and memory. However, the way perceptual and memory processes cooperate when we navigate in our everyday life environment remains poorly understood. We studied a stroke patient presenting a brain lesion in the right PHC, which resulted in a mild and quantifiable topographic agnosia, and allowed us to investigate the role of this structure in overt place recognition. Photographs of personally familiar and unfamiliar places were displayed during functional magnetic resonance imaging (fMRI). Familiar places were either recognized or unrecognized by the patient and 6 age- and education-matched controls in a visual post-scan recognition test. In fMRI, recognized places were associated with a network comprising the fusiform gyrus in the intact side, but also the right anterior PHC, which included the lesion site. Moreover, this right PHC showed increased connectivity with the left homologous PHC in the intact hemisphere. By contrasting recognized with unrecognized familiar places, we replicate the finding of the joint involvement of the retrosplenial cortex, occipito-temporal areas, and posterior parietal cortex in place recognition. This study shows that the ability for left and right anterior PHC to communicate despite the neurological damage conditioned place recognition success in this patient. It further highlights a hemispheric asymmetry in this process, by showing the fundamental role of the right PHC in topographic agnosia. PMID:26909331

  4. Hurt but still alive: Residual activity in the parahippocampal cortex conditions the recognition of familiar places in a patient with topographic agnosia☆

    PubMed Central

    van Assche, Mitsouko; Kebets, Valeria; Lopez, Ursula; Saj, Arnaud; Goldstein, Rachel; Bernasconi, Françoise; Vuilleumier, Patrik; Assal, Frédéric

    2016-01-01

    The parahippocampal cortex (PHC) participates in both perception and memory. However, the way perceptual and memory processes cooperate when we navigate in our everyday life environment remains poorly understood. We studied a stroke patient presenting a brain lesion in the right PHC, which resulted in a mild and quantifiable topographic agnosia, and allowed us to investigate the role of this structure in overt place recognition. Photographs of personally familiar and unfamiliar places were displayed during functional magnetic resonance imaging (fMRI). Familiar places were either recognized or unrecognized by the patient and 6 age- and education-matched controls in a visual post-scan recognition test. In fMRI, recognized places were associated with a network comprising the fusiform gyrus in the intact side, but also the right anterior PHC, which included the lesion site. Moreover, this right PHC showed increased connectivity with the left homologous PHC in the intact hemisphere. By contrasting recognized with unrecognized familiar places, we replicate the finding of the joint involvement of the retrosplenial cortex, occipito-temporal areas, and posterior parietal cortex in place recognition. This study shows that the ability for left and right anterior PHC to communicate despite the neurological damage conditioned place recognition success in this patient. It further highlights a hemispheric asymmetry in this process, by showing the fundamental role of the right PHC in topographic agnosia. PMID:26909331

  5. Administration of activated glial condition medium in the nucleus accumbens extended extinction and intensified reinstatement of methamphetamine-induced conditioned place preference.

    PubMed

    Arezoomandan, Reza; Moradi, Marzieh; Attarzadeh-Yazdi, Ghassem; Tomaz, Carlos; Haghparast, Abbas

    2016-07-01

    Methamphetamine (METH) is a psychostimulant drug with significant abuse potential and neurotoxic effects. A high percentage of users relapse to use after detoxification and no effective medication has been developed for treatment of METH addiction. Developing evidences indicated the role of glial cells in drugs abused related phenomena. However, little is known about the role of these cells in the maintenance and reinstatement of METH-seeking behaviors. Therefore, the current study was conducted to clarify the role of glial cells in the maintenance and reinstatement of METH-induced conditioned place preference (CPP) in rats. Astrocyte condition medium (ACM) and neuroglia conditioned medium (NCM) are liquid mediums prepared from primary astrocyte and neuroglia cells. These mediums seem to contain many factors that release by glia cells. CPP was induced by systemic administration of METH (1mg/kg for 5days, s.c.). Following the establishment of CPP, the rats were given daily bilateral injections (0.5μl/side) of either vehicle, ACM or NCM into the nucleus accumbens (NAc) and then were tested for the maintenance and reinstatement. Intra-NAc administration of ACM treated with METH, could extend the extinction period and also, intensified the magnitude of METH reinstatement. Furthermore, intra-accumbal administration of NCM treated with METH notably delayed the extinction period by four days and significantly increased the magnitude of CPP score in the reinstatement phase compared to the post-test phase. Collectively, these findings suggested that activation of glial cells may be involved in the maintenance and reinstatement of METH-seeking behaviors. It provides new evidence that glia cells might be considered as a potential target for the treatment of METH addiction. PMID:27346277

  6. The Importance of Outdoor Activity and Place Attachment to Adolescent Development in Coös County, New Hampshire. Paper 208. New Hampshire and New England Issue Brief No. 37

    ERIC Educational Resources Information Center

    Seaman, Jayson; McLaughlin, Sean

    2013-01-01

    This brief discusses the rates of participation in structured and unstructured outdoor activities as Coös County youth age, along with the relationship between outdoor activity involvement and indicators of place attachment throughout this period. The analysis is based on data collected between 2008 and 2013 as part of the Carsey Institute's Panel…

  7. The Space Place: Adventures in Informal Education - and Lessons Learned

    NASA Astrophysics Data System (ADS)

    Fisher, D.; Leon, N.

    2001-12-01

    Informal education settings provide unique opportunities to convey Earth and space science learning to a variety of audiences. The NASA Space Place suite of outreach products and activities include deliverables to both the formal and the informal education arenas. The question is, how can Earth and space science efforts best create high-quality products and activities for the informal education sector- and how can these products and activities be effectively disseminated to these audiences? This session will describe the approach by a small outreach team for NASA's New Millennium Program (NMP) Space Place effort. The Space Place team's approach has been three-fold: 1) develop a suite of products designed to appeal to (and educate) the informal education audience, 2) disseminate these products through leveraged distribution channels which serve the informal education community, and 3) invite participation by missions beyond those within NMP, but rather NASA-wide - for a richer and broader message, and a greater variety of content The informal education audience served by the Space Place can be found in science centers, museums, planetariums, libraries, community centers, and community organizations. This informal education audience seeks to be entertained as well as to be educated, and this audience often includes multiple generations. Personnel at informal education venues may or may not have a science background, may or may not have significant training in conducting activities, and may, as often as not, be volunteers. As a result of valuable lessons learned, Space Place materials developed for informal education settings attempt to be adaptable for multiple age groups, and easy to administer. Dissemination to the informal education community could be a daunting effort. But another lesson learned by the Space Place team is the value of alliances with national organizations within that community. These alliances make distribution of the Space Place activities and

  8. The value of place

    NASA Astrophysics Data System (ADS)

    Dentzau, Michael W.

    2014-03-01

    This commentary seeks to expand the dialogue on place-based science education presented in Katie Lynn Brkich's article, where the connections fifth grade students make between their formal earth science curriculum and their lived experiences are highlighted. The disconnect between the curriculum the students are offered and their immediate environment is clear, and we are presented with examples of how they strive to make connections between the content and what they are familiar with—namely their surroundings. "Place" is identified as a term with complex meanings and interpretations, even in the scope of place-based science education, and understanding how the term is used in any given scenario is essential to understanding the implications of place-based education. Is place used as a location, locale or a sense of place? To understand "place" is to acknowledge that for the individual, it is highly situational, cultural and personal. It is just such attributes that make place-based education appealing, and potentially powerful, pedagogically on one hand, yet complex for implementation on the other. The argument is posed that place is particularly important in the context of education about the environment, which in its simplest manifestation, connects formal science curriculum to resources that are local and tangible to students. The incorporation of place in such a framework seeks to bridge the gap between formal school science subjects and students' lived experiences, yet acknowledges the tensions that can arise between accommodating place meanings and the desire to acculturate students into the language of the scientific community. The disconnect between guiding policy frameworks and the reality of the Next Generation Science Standards is addressed opening an avenue for further discussion of the importance of socio-cultural frameworks of science learning in an ever increasing era of accountability.

  9. Changes in Familiarity with and Willingness to Take Preexposure Prophylaxis in a Longitudinal Study of Highly Sexually Active Gay and Bisexual Men

    PubMed Central

    Grov, Christian; Rendina, H. Jonathon; Whitfield, Thomas H.F.; Ventuneac, Ana

    2016-01-01

    Abstract Purpose: For gay and bisexual men (GBM), research suggests that familiarity with preexposure prophylaxis (PrEP) has been increasing since being approved by the United States Food and Drug Administration in 2012. However, it is less clear how willingness to start using PrEP has changed over time. Likewise, some have expressed concerns regarding the potential for risk compensation (i.e., reduced condom use) were one to start PrEP; however, again, it is unclear how risk compensation may have changed over time. Methods: We conducted baseline and 12-month assessments with 158 highly sexually active HIV-negative GBM in New York City who were assessed between 2011 and 2014. We examined change over time both between participants (based on when they entered the study), as well as within each participant (over the 12 months of his involvement). Results: Familiarity with PrEP increased over time (both between and within participants); however, willingness to take PrEP did not change (neither between nor within participants). Few men believed taking PrEP would cause their condomless anal sex (CAS) to increase and this did not change over time. However, a majority believed PrEP would increase temptation for CAS, and this did not change over time within participants. Sexual compulsivity symptomology was associated with higher willingness to take PrEP and perceiving that PrEP would increase one's temptations for CAS. Furthermore, recent CAS was associated with greater willingness to take PrEP, a perception that PrEP would increase one's likelihood to engage in CAS, and a perception that being on PrEP would increase one's temptation for CAS. Conclusions: Participants became more familiar with PrEP over time; however, willingness to start PrEP did not change, and this may serve as an opportunity for providers to discuss PrEP with their patients. Men who engaged in CAS were interested in PrEP and preexisting patterns of sexual behavior may be the primary determinant of CAS

  10. The Mushroom Place. Part III.

    ERIC Educational Resources Information Center

    Schlichter, Carol

    1978-01-01

    The final installment of a series of articles on the "Mushroom Place" learning center program, which involves creative thinking activities for young, gifted students, describes "Doing It the Hard Way," a performance task which involves the actual construction of objects from a selected set of materials in the absence of the usual project tools.…

  11. Schooling Out of Place

    ERIC Educational Resources Information Center

    McConaghy, Cathryn

    2006-01-01

    Education in rural communities is an interesting site for an analysis of the relationship between place and the cultural politics of schooling. In particular the movements of people, ideas and practices to and from, and also within, rural places suggest the need for theorizing on rural education to consider the relevance of new mobility…

  12. Teaching Bodies in Place

    ERIC Educational Resources Information Center

    Jones, Stephanie; Woglom, James F.

    2013-01-01

    Background/Context: This piece draws on literature in justice-oriented teacher education, feminist pedagogy, and postmodern notions of bodies and place to make sense of data generated from a three-year study of an undergraduate teacher education course. A feminist lens was used to engage a body- and place-focused pedagogy that aimed to engage…

  13. The Case for Place

    ERIC Educational Resources Information Center

    Thomas, Lisa Carlucci

    2012-01-01

    Bookstores, record stores, libraries, Facebook: these places--both physical and virtual--demonstrate an established and essential purpose as centers of community, expertise, convenience, immediacy, and respect. Yet as digital, mobile, and social shifts continue to transform culture and interactions, these spaces and places transform, too.…

  14. Long-Term Post-Stroke Changes Include Myelin Loss, Specific Deficits in Sensory and Motor Behaviors and Complex Cognitive Impairment Detected Using Active Place Avoidance

    PubMed Central

    Li, Jie; Ooi, Evelyn; Bloom, Jonathan; Poon, Carrie; Lax, Daniel; Rosenbaum, Daniel M.; Barone, Frank C.

    2013-01-01

    Persistent neurobehavioral deficits and brain changes need validation for brain restoration. Two hours middle cerebral artery occlusion (tMCAO) or sham surgery was performed in male Sprague-Dawley rats. Neurobehavioral and cognitive deficits were measured over 10 weeks included: (1) sensory, motor, beam balance, reflex/abnormal responses, hindlimb placement, forepaw foot fault and cylinder placement tests, and (2) complex active place avoidance learning (APA) and simple passive avoidance retention (PA). Electroretinogram (ERG), hemispheric loss (infarction), hippocampus CA1 neuronal loss and myelin (Luxol Fast Blue) staining in several fiber tracts were also measured. In comparison to Sham surgery, tMCAO surgery produced significant deficits in all behavioral tests except reflex/abnormal responses. Acute, short lived deficits following tMCAO were observed for forelimb foot fault and forelimb cylinder placement. Persistent, sustained deficits for the whole 10 weeks were exhibited for motor (p<0.001), sensory (p<0.001), beam balance performance (p<0.01) and hindlimb placement behavior (p<0.01). tMCAO produced much greater and prolonged cognitive deficits in APA learning (maximum on last trial of 604±83% change, p<0.05) but only a small, comparative effect on PA retention. Hemispheric loss/atrophy was measured 10 weeks after tMCAO and cross-validated by two methods (e.g., almost identical % ischemic hemispheric loss of 33.4±3.5% for H&E and of 34.2±3.5% for TTC staining). No visual dysfunction by ERG and no hippocampus neuronal loss were detected after tMCAO. Fiber tract damage measured by Luxol Fast Blue myelin staining intensity was significant (p<0.01) in the external capsule and striatum but not in corpus callosum and anterior commissure. In summary, persistent neurobehavioral deficits were validated as important endpoints for stroke restorative research in the future. Fiber myelin loss appears to contribute to these long term behavioral dysfunctions and can be

  15. Long-term post-stroke changes include myelin loss, specific deficits in sensory and motor behaviors and complex cognitive impairment detected using active place avoidance.

    PubMed

    Zhou, Jin; Zhuang, Jian; Li, Jie; Ooi, Evelyn; Bloom, Jonathan; Poon, Carrie; Lax, Daniel; Rosenbaum, Daniel M; Barone, Frank C

    2013-01-01

    Persistent neurobehavioral deficits and brain changes need validation for brain restoration. Two hours middle cerebral artery occlusion (tMCAO) or sham surgery was performed in male Sprague-Dawley rats. Neurobehavioral and cognitive deficits were measured over 10 weeks included: (1) sensory, motor, beam balance, reflex/abnormal responses, hindlimb placement, forepaw foot fault and cylinder placement tests, and (2) complex active place avoidance learning (APA) and simple passive avoidance retention (PA). Electroretinogram (ERG), hemispheric loss (infarction), hippocampus CA1 neuronal loss and myelin (Luxol Fast Blue) staining in several fiber tracts were also measured. In comparison to Sham surgery, tMCAO surgery produced significant deficits in all behavioral tests except reflex/abnormal responses. Acute, short lived deficits following tMCAO were observed for forelimb foot fault and forelimb cylinder placement. Persistent, sustained deficits for the whole 10 weeks were exhibited for motor (p<0.001), sensory (p<0.001), beam balance performance (p<0.01) and hindlimb placement behavior (p<0.01). tMCAO produced much greater and prolonged cognitive deficits in APA learning (maximum on last trial of 604±83% change, p<0.05) but only a small, comparative effect on PA retention. Hemispheric loss/atrophy was measured 10 weeks after tMCAO and cross-validated by two methods (e.g., almost identical % ischemic hemispheric loss of 33.4±3.5% for H&E and of 34.2±3.5% for TTC staining). No visual dysfunction by ERG and no hippocampus neuronal loss were detected after tMCAO. Fiber tract damage measured by Luxol Fast Blue myelin staining intensity was significant (p<0.01) in the external capsule and striatum but not in corpus callosum and anterior commissure. In summary, persistent neurobehavioral deficits were validated as important endpoints for stroke restorative research in the future. Fiber myelin loss appears to contribute to these long term behavioral dysfunctions and can be

  16. Gateway to New Atlantis Attraction Takes Shape

    NASA Video Gallery

    The home of space shuttle Atlantis continues taking shape at the Kennedy Space Center Visitor Complex. Crews placed the nose cone atop the second of a replica pair of solid rocket boosters. A life-...

  17. About Maggie's Place.

    ERIC Educational Resources Information Center

    Emmens, Carol E.

    1982-01-01

    Describes "Maggie's Place," the library computer system of the Pikes Peak Library District, Colorado Springs, Colorado, noting its use as an electronic card catalog and community information file, accessibility by home users and library users, and terminal considerations. (EJS)

  18. Artist Place Settings

    ERIC Educational Resources Information Center

    Pellegrino, Linda

    2009-01-01

    Art history can be a little dry at times, but the author is always trying to incorporate new ways of teaching it. In this article, she describes a project in which students were to create a place setting out of clay that had to be unified through a famous artist's style. This place setting had to consist of at least five pieces (dinner plate, cup…

  19. The Take Action Project

    ERIC Educational Resources Information Center

    Boudreau, Sue

    2010-01-01

    The Take Action Project (TAP) was created to help middle school students take informed and effective action on science-related issues. The seven steps of TAP ask students to (1) choose a science-related problem of interest to them, (2) research their problem, (3) select an action to take on the problem, (4) plan that action, (5) take action, (6)…

  20. Take Steps Toward a Healthier Life | Poster

    Cancer.gov

    The National Institutes of Health (NIH) is promoting wellness by encouraging individuals to take the stairs. In an effort to increase participation in this program, NIH has teamed up with Occupational Health Services (OHS). OHS is placing NIH-sponsored “Take the Stairs” stickers on stair entrances, stair exits, and elevators.

  1. Designing Places for Learning.

    ERIC Educational Resources Information Center

    Meek, Anne, Ed.

    This book presents information about the condition of schools around the United States. It also describes the link between architecture and academic success and offers suggestions for improving the design of existing and future school buildings. Eleven articles look at schools as places of deep meaning and show how that view can alter approaches…

  2. Teaching With Historic Places.

    ERIC Educational Resources Information Center

    Greenberg, Ronald M., Ed.

    1993-01-01

    Designed for social studies educators, this theme issue presents 11 articles about historic places that feature a variety of ideas for elementary and secondary lesson plans, curricula, and program development. The articles are: (1) "Where did History Happen?" (Beth M. Boland); (2) "Creating a Partnership" (Carol D. Shull); (3) "Heritage Education:…

  3. Creativity: Does Place Matter?

    ERIC Educational Resources Information Center

    Bradley, Finbarr

    2012-01-01

    This article argues that creativity has the greatest potential to flourish if a learning environment is embedded within a community that emphasises a deep sense of place. Yet in a globalised world, rootedness is often regarded as antithetical to creativity. But far from representing dead artefacts that are anti-modern and non-economic, culture and…

  4. The Value of Place

    ERIC Educational Resources Information Center

    Dentzau, Michael W.

    2014-01-01

    This commentary seeks to expand the dialogue on place-based science education presented in Katie Lynn Brkich's article, where the connections fifth grade students make between their formal earth science curriculum and their lived experiences are highlighted. The disconnect between the curriculum the students are offered and their immediate…

  5. Finding Place in Education

    ERIC Educational Resources Information Center

    Peters, Chris

    2011-01-01

    As a society, we are less and less comfortable in our localities. We have embraced the idea of a globalized placelessness, where everything, everywhere, resonates with a sameness. What do we lose, educationally and in society at large, when we reduce our inhabited places to those components that provide material wealth alone? If students and…

  6. SR-71 Taking Off

    NASA Technical Reports Server (NTRS)

    1990-01-01

    One of three U.S. Air Force SR-71 reconnaissance aircraft originally retired from operational service and loaned to NASA for a high-speed research program retracts its landing gear after taking off from NASA's Ames-Dryden Flight Research Facility (later Dryden Flight Research Center), Edwards, California, on a 1990 research flight. One of the SR-71As was later returned to the Air Force for active duty in 1995. Data from the SR-71 high-speed research program will be used to aid designers of future supersonic/hypersonic aircraft and propulsion systems. Two SR-71 aircraft have been used by NASA as testbeds for high-speed and high-altitude aeronautical research. The aircraft, an SR-71A and an SR-71B pilot trainer aircraft, have been based here at NASA's Dryden Flight Research Center, Edwards, California. They were transferred to NASA after the U.S. Air Force program was cancelled. As research platforms, the aircraft can cruise at Mach 3 for more than one hour. For thermal experiments, this can produce heat soak temperatures of over 600 degrees Fahrenheit (F). This operating environment makes these aircraft excellent platforms to carry out research and experiments in a variety of areas -- aerodynamics, propulsion, structures, thermal protection materials, high-speed and high-temperature instrumentation, atmospheric studies, and sonic boom characterization. The SR-71 was used in a program to study ways of reducing sonic booms or over pressures that are heard on the ground, much like sharp thunderclaps, when an aircraft exceeds the speed of sound. Data from this Sonic Boom Mitigation Study could eventually lead to aircraft designs that would reduce the 'peak' overpressures of sonic booms and minimize the startling affect they produce on the ground. One of the first major experiments to be flown in the NASA SR-71 program was a laser air data collection system. It used laser light instead of air pressure to produce airspeed and attitude reference data, such as angle of

  7. The Right Place, The Right Time

    ERIC Educational Resources Information Center

    O'Callaghan, William G.; Irish, Charles M.

    2006-01-01

    Superintendents are in the right place at the right time to take advantage of a golden opportunity to reverse a trend that threatens the nation's schools and communities. They are now uniquely positioned to stop the retreat of good-hearted, well-intentioned citizens from public life. In this article, the authors present perpetual traps that…

  8. Taking multiple medicines safely

    MedlinePlus

    ... medlineplus.gov/ency/patientinstructions/000883.htm Taking multiple medicines safely To use the sharing features on this ... directed. Why you may Need More Than one Medicine You may take more than one medicine to ...

  9. Space Place Prime

    NASA Technical Reports Server (NTRS)

    Fitzpatrick, Austin J.; Novati, Alexander; Fisher, Diane K.; Leon, Nancy J.; Netting, Ruth

    2013-01-01

    Space Place Prime is public engagement and education software for use on iPad. It targets a multi-generational audience with news, images, videos, and educational articles from the Space Place Web site and other NASA sources. New content is downloaded daily (or whenever the user accesses the app) via the wireless connection. In addition to the Space Place Web site, several NASA RSS feeds are tapped to provide new content. Content is retained for the previous several days, or some number of editions of each feed. All content is controlled on the server side, so features about the latest news, or changes to any content, can be made without updating the app in the Apple Store. It gathers many popular NASA features into one app. The interface is a boundless, slidable- in-any-direction grid of images, unique for each feature, and iconized as image, video, or article. A tap opens the feature. An alternate list mode presents menus of images, videos, and articles separately. Favorites can be tagged for permanent archive. Face - book, Twitter, and e-mail connections make any feature shareable.

  10. Implementation of a nurse-led behaviour change intervention to support medication taking in type 2 diabetes: beyond hypothesised active ingredients (SAMS Consultation Study)

    PubMed Central

    2014-01-01

    Background Implementation of trial interventions is rarely assessed, despite its effects on findings. We assessed the implementation of a nurse-led intervention to facilitate medication adherence in type 2 diabetes (SAMS) in a trial against standard care in general practice. The intervention increased adherence, but not through the hypothesised psychological mechanism. This study aimed to develop a reliable coding frame for tape-recorded consultations, assessing both a priori hypothesised and potential active ingredients observed during implementation, and to describe the delivery and receipt of intervention and standard care components to understand how the intervention might have worked. Methods 211 patients were randomised to intervention or comparison groups and 194/211 consultations were tape-recorded. Practice nurses delivered standard care to all patients and motivational and action planning (implementation intention) techniques to intervention patients only. The coding frame was developed and piloted iteratively on selected tape recordings until a priori reliability thresholds were achieved. All tape-recorded consultations were coded and a random subsample double-coded. Results Nurse communication, nurse-patient relationship and patient responses were identified as potential active ingredients over and above the a priori hypothesised techniques. The coding frame proved reliable. Intervention and standard care were clearly differentiated. Nurse protocol adherence was good (M (SD) = 3.95 (0.91)) and competence of intervention delivery moderate (M (SD) = 3.15 (1.01)). Nurses frequently reinforced positive beliefs about taking medication (e.g., 65% for advantages) but rarely prompted problem solving of negative beliefs (e.g., 21% for barriers). Patients’ action plans were virtually identical to current routines. Nurses showed significantly less patient-centred communication with the intervention than comparison group. Conclusions It is feasible to

  11. Synthesis and Insecticidal Activity of Spinosyns with C9-O-Benzyl Bioisosteres in Place of the 2',3',4'-Tri-O-methyl Rhamnose.

    PubMed

    Oliver, M Paige; Crouse, Gary D; Demeter, David A; Sparks, Thomas C

    2015-06-17

    The spinosyns are fermentation-derived natural products active against a wide range of insect pests. They are structurally complex, consisting of two sugars (forosamine and rhamnose) coupled to a macrocyclic tetracycle. Removal of the rhamnose sugar results in a >100-fold reduction in insecticidal activity. C9-O-benzyl analogues of spinosyn D were synthesized to determine if the 2',3',4'-tri-O-methyl rhamnose moiety could be replaced with a simpler, synthetic bioisostere. Insecticidal activity was evaluated against larvae of Spodoptera exigua (beet armyworm) and Helicoverpa zea (corn earworm). Whereas most analogues were far less active than spinosyn D, a few of the C9-O-benzyl analogues, such as 4-CN, 4-Cl, 2-isopropyl, and 3,5-diOMe, were within 3-15 times the activity of spinosyn D for larvae of S. exigua and H. zea. Thus, although not yet quite as effective, synthetic bioisosteres can substitute for the naturally occurring 2',3',4'-tri-O-methyl rhamnose moiety. PMID:25993441

  12. Urban Environmental Education and Sense of Place

    ERIC Educational Resources Information Center

    Kudryavtsev, Alexey

    2013-01-01

    Urban environmental educators are trying to connect students to the urban environment and nature, and thus develop a certain sense of place. To do so, educators involve students in environmental stewardship, monitoring, activism, and outdoor recreation in cities. At the same time, sense of place has been linked to pro-environmental behaviors and…

  13. 41 CFR 102-75.135 - If no hazardous substance activity took place on the property, what specific information must an...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... DISPOSAL Utilization of Excess Real Property Title Report § 102-75.135 If no hazardous substance activity... (reporting agency) has determined, in accordance with regulations issued by EPA at 40 CFR part 373, that... report? 102-75.135 Section 102-75.135 Public Contracts and Property Management Federal...

  14. 41 CFR 102-75.135 - If no hazardous substance activity took place on the property, what specific information must an...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... DISPOSAL Utilization of Excess Real Property Title Report § 102-75.135 If no hazardous substance activity... (reporting agency) has determined, in accordance with regulations issued by EPA at 40 CFR part 373, that... report? 102-75.135 Section 102-75.135 Public Contracts and Property Management Federal...

  15. Just Being Kids: Supports and Services for Infants and Toddlers and Their Families in Everyday Routines, Activities, and Places. [Videotape with Facilitator's Guide].

    ERIC Educational Resources Information Center

    Edelman, Larry

    Each of the six stories on this 50-minute videotape demonstrates recommended practices as therapists and early childhood specialists work collaboratively with families to achieve meaningful goals for their children in everyday routines and activities. "Just Being Kids" was developed for use in both pre-service and in-service training programs with…

  16. System-Events Toolbox--Activating Urban Places for Social Cohesion through Designing a System of Events That Relies on Local Resources

    ERIC Educational Resources Information Center

    Fassi, Davide; Motter, Roberta

    2014-01-01

    This paper is a reflection on the use of public spaces in towns and the development of a system-events toolbox to activate them towards social cohesion. It is the result of a 1 year action research developed together with POLIMI DESIS Lab of the Department of Design to develop design solutions to open up the public spaces of the campus to the…

  17. Shatter the Glassy Stare: Implementing Experiential Learning in Higher Education--"A Companion Piece to Place as Text: Approaches to Active Learning." National Collegiate Honors Council Monograph Series

    ERIC Educational Resources Information Center

    Machonis, Peter A., Ed.

    2008-01-01

    This monograph presents in some detail the ways in which Faculty Institutes--professional development opportunities where instructors immerse themselves in site-specific learning activities exactly as students would, though only for several days--allow participants to acquire the skill to design such adventures elsewhere for their own students.…

  18. Rover Takes a Sunday Drive

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This animation, made with images from the Mars Exploration Rover Spirit hazard-identification camera, shows the rover's perspective of its first post-egress drive on Mars Sunday. Engineers drove Spirit approximately 3 meters (10 feet) toward its first rock target, a football-sized, mountain-shaped rock called Adirondack. The drive took approximately 30 minutes to complete, including time stopped to take images. Spirit first made a series of arcing turns totaling approximately 1 meter (3 feet). It then turned in place and made a series of short, straightforward movements totaling approximately 2 meters (6.5 feet).

  19. In-place HEPA filter penetration test

    SciTech Connect

    Bergman, W.; Wilson, K.; Elliott, J.

    1997-08-01

    We have demonstrated the feasibility of conducting penetration tests on high efficiency particulate air (HEPA) filters as installed in nuclear ventilation systems. The in-place penetration test, which is designed to yield equivalent penetration measurements as the standard DOP efficiency test, is based on measuring the aerosol penetration of the filter installation as a function of particle size using a portable laser particle counter. This in-place penetration test is compared to the current in-place leak test using light scattering photometers for single HEPA filter installations and for HEPA filter plenums using the shroud method. Test results show the in-place penetration test is more sensitive than the in-place leak test, has a similar operating procedure, but takes longer to conduct. Additional tests are required to confirm that the in-place penetration test yields identical results as the standard dioctyl phthalate (DOP) penetration test for HEPA filters with controlled leaks in the filter and gasket and duct by-pass leaks. Further development of the procedure is also required to reduce the test time before the in-place penetration test is practical. 14 refs., 14 figs., 3 tabs.

  20. Deprivation amplification revisited; or, is it always true that poorer places have poorer access to resources for healthy diets and physical activity?

    PubMed Central

    Macintyre, Sally

    2007-01-01

    Background It has commonly been suggested (including by this author) that individual or household deprivation (for example, low income) is amplified by area level deprivation (for example, lack of affordable nutritious food or facilities for physical activity in the neighbourhood). Discussion The idea of deprivation amplification has some intuitive attractiveness and helps divert attention away from purely individual determinants of diet and physical activity, and towards health promoting or health damaging features of the physical and social environment. Such environmental features may be modifiable, and environmental changes may help promote healthier behaviors. However, recent empirical examination of the distribution of facilities and resources shows that location does not always disadvantage poorer neighbourhoods. This suggests that we need: a) to ensure that theories and policies are based on up-to-date empirical evidence on the socio-economic distribution of neighbourhood resources, and b) to engage in further research on the relative importance of, and interactions between, individual and environmental factors in shaping behavior. Summary In this debate paper I suggest that it may not always be true that poorer neighbourhoods are more likely to lack health promoting resources, and to be exposed to more health damaging resources. The spatial distribution of environmental resources by area socioeconomic status may vary between types of resource, countries, and time periods. It may also be that the presence or absence of resources is less important than their quality, their social meaning, or local perceptions of their accessibility and relevance. PMID:17683624

  1. Taking the Long View

    ERIC Educational Resources Information Center

    Bennett, Robert B., Jr.

    2010-01-01

    Legal studies faculty need to take the long view in their academic and professional lives. Taking the long view would seem to be a cliched piece of advice, but too frequently legal studies faculty, like their students, get focused on meeting the next short-term hurdle--getting through the next class, grading the next stack of papers, making it…

  2. [Effect of iontophoretically administered L-DOPA and ketamin on the impulse activity of the somatomotor cortex neurons during the conditioned placing movements].

    PubMed

    Khorievin, V I

    2010-01-01

    Interactions between the neuronal dopamine and NMDA glutamate receptors were investigated by iontophoresis of L-DOPA and ketamin to 19 single cortical neurons of the somatomotor cortex neurons in cats performing the operant reflex. L-DOPA producing bursts of 8-12 impulses that led to the significant increase of the total number of spikes related to the movements and insignificant decreased the power or the average number of spikes in a conditional response. Effects of ketamin on impulse activity were multidirectional resulting in most cases (16 cells) in the significant increase of the response power and in other three cells producing the suppression of discharges related to movements. It is supposed that following the ketamin iontophoresis the facilitation of conditional responses was caused by the blocking of the NMDA-glutamatergic transmission to intracortical inhibitory neurons, whereas inhibition of conditioned responses of other cortical cells was produced by blocking NMDA-glutamatergic transmission to pyramidal neurons. The total number of spikes associated with the performance of movements following the joint application of L-DOPA and ketamin was significantly higher compared with the effect of the isolated L-DOPA iontophoresis. These data indicate the NMDA-glutamatergic transmission, which plays an important role in shaping the cortical neuron responses in the performance of behavioral reactions may be modulated by L-DOPA. PMID:21469313

  3. Taking a Stand as a Student-Centered Research University: Active and Collaborative Learning Meets Scholarship of Teaching at the University of Alabama

    ERIC Educational Resources Information Center

    Bonner, Judy

    2010-01-01

    This article introduces the University of Alabama, outlines efforts in the scholarship of teaching and active and collaborative learning, and describes plans for continuing the instructional focus as a student-centered research university, where teaching is viewed as a scholarly activity and students are actively engaged in their learning.

  4. Give/Take

    2007-09-12

    Give and Take are set of companion utilities that allow a secure transfer of files from one user to another without exposing the files to third parties. The named files are copied to a spool area. The reciever can retrieve the files by running the "take" program. Ownership of the files remains with the giver until they are taken. Certain users may be limited to take files only from specific givers. For these users, filesmore » may only be taken from givers who are members of the gt-uid-group where uid is the UNIX id of the limited user.« less

  5. Orion Spacecraft Takes Shape

    NASA Video Gallery

    Technicians move the two halves of the Orion crew exploration vehicle's crew module into place to fuse them together at NASA's Michoud Assembly Facility in New Orleans, La. The Lockheed Martin Orio...

  6. Development and Validation of the Place-Based Learning and Constructivist Environment Survey (PLACES)

    ERIC Educational Resources Information Center

    Zandvliet, David B.

    2012-01-01

    Learning environment studies acknowledge that learning takes place within the social realm and that social conditions contribute to the quality of both learning and experience. This can be said to be especially true for environmental learning programs. To access information about students' perceptions of their learning environment, a robust…

  7. General practice 'going places'.

    PubMed

    Hughes, C

    1992-05-01

    This paper, which was presented at the Annual General Meeting of the Royal Australian College of General Practitioners in September 1991, outlines possible roles for the general practitioner in the public health system. Four fundamental steps need to be taken: affirmative action by health boards to include GPs in all activities; representation of the RACGP on health boards; adequate remuneration; and part time employment of GPs in all health care delivery service units. PMID:1520131

  8. Take Your Medicines Safely

    MedlinePlus Videos and Cool Tools

    ... better, the antibiotic is working in killing the bacteria, but it might not completely give what they call a "bactericidal effect." That means taking the bacteria completely out of the system. It might be ...

  9. Refashioning One’s Place in Time: Stories of Household Downsizing in Later Life

    PubMed Central

    Luborsky, Mark R.; Lysack, Catherine L.; Van Nuil, Jennifer

    2011-01-01

    Older adults face a daunting task: while continuing engagements in multiple relationships, investment in their own and others’ futures, and developing life interests and capacities, they also reexamine and sometimes reconfigure the place where their social lives and objects are housed. Some relocate, downsize, to a new smaller place and reducing possessions to ensure an environment supportive of their capacities and desired daily activities. This article examines how key contours of the experiences of place during residential downsizing are infused with unexpectedly heightened awareness and cultivation of one’s sense of place in multiple timeframes. In a discovery mode, the downsizing stories of 40 older adults in southeast Michigan are examined. Findings indicate conflicting temporalities and the natures of cognitions related to decision-making and thinking about being leave-taking and being in place. Findings also highlight in particular how making sense of one’s place is predicated on notions of its time, of being on time and downsizing on time. Further, these characterizations of the lived worlds of older adults’ modes of conceptualizing the nature of downsizing show how an understanding of the meaningfulness of place in later life relocations requires a layered sense of home as places-in multiple timelines. PMID:21765597

  10. [Cooking as a therapy for dangerous mental health patients: controlled risk-taking].

    PubMed

    Geay, Janique; Schmitt, Stéphane; Bouchard, Jean-Pierre

    2015-01-01

    Among the range of therapeutic mediators used with dangerous mental health patients in the unit for dangerous patients in Cadillac, cooking holds an important place. Led by caregivers, this activity has undeniable positive effects for the psychotic and non-psychotic patients taking part. These effects concern notably their capacities for conception, creation, organisation, execution, sensation, collaboration and socialisation. For some patients, it is also the opportunity to take the drama out of handling utensils which they previously used as weapons. As the risk factors are controlled before and during the activity, no dangerous acting out has ever occurred. PMID:26143218

  11. Use of an infrared sensor system to take long-term bedside measurements of rest-activity patterns in the elderly with dementia.

    PubMed

    Nakano, Toshio; Koyama, Emi; Nakamura, Toshiyuki; Ito, Takeo; Tamura, Koji; Yaginuma, Masaaki

    2002-06-01

    In order to study long-term rest-activity patterns of elderly residents in care facilities, an infrared sensor system was developed. This sensor system detects a resident's presence or absence from their bed and their activity with little inconvenience. Using this system, the rest-activity patterns of two elderly people with dementia was assessed over a period of 3 months. For both subjects, frequent activity peaks and absences from their beds were often observed during the night. Such a sensor system will be useful for evaluating the sleep-wake rhythms of people with sleep disorders. PMID:12047598

  12. Remembering Places: Student Reliance on Place in Timed Essays

    ERIC Educational Resources Information Center

    Evans, Donna

    2009-01-01

    This is the story of a research journey that follows the trail of a novel evaluand--"place." I examine place as mentioned by rising juniors in timed exams. Using a hybridized methodology--the qualitative approach of a hermeneutic dialectic process as described by Guba and Lincoln (1989), and the quantitative evidence of place mention--I query…

  13. Teachable Moment: Google Earth Takes Us There

    ERIC Educational Resources Information Center

    Williams, Ann; Davinroy, Thomas C.

    2015-01-01

    In the current educational climate, where clearly articulated learning objectives are required, it is clear that the spontaneous teachable moment still has its place. Authors Ann Williams and Thomas Davinroy think that instructors from almost any discipline can employ Google Earth as a tool to take advantage of teachable moments through the…

  14. 37 CFR 41.157 - Taking testimony.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... expected to be used. A party requesting cross-examination testimony of more than one witness may choose the... testimony and must list: (i) The time and place of the deposition, (ii) The name and address of the witness... taking testimony. (1) Each witness before giving a deposition shall be duly sworn according to law by...

  15. Geographic Landscape of Place Names.

    ERIC Educational Resources Information Center

    Gritzner, Charles F.

    1988-01-01

    Explores the origins of many geographic place names. Suggests that using toponyms (place names) to study geographic conditions of an area offers rich diversity for the teaching of map skills and regional geography. (DH)

  16. Got Unwanted Pills? Drug Take-Back Day Is April 30

    MedlinePlus

    ... 158560.html Got Unwanted Pills? Drug Take-Back Day Is April 30 National effort coordinates drop-off ... drop-off centers nationwide during Drug Take-Back Day, which takes place this year on Saturday, April ...

  17. Singapore Math: Place Value, Computation & Number Sense. [CD-ROM

    ERIC Educational Resources Information Center

    Chen, Sandra

    2008-01-01

    "Singapore Math: Place Value, Computation & Number Sense" is a six-part presentation on CD-ROM that can be used by individual teachers or an entire school. The author takes primary to upper elementary grade teachers through place value skills with each of the computational operations: addition, subtraction, multiplication, and division. She gives…

  18. Creating Sacred Places for Children in Grades 4-6.

    ERIC Educational Resources Information Center

    Fox, Sandra J.

    This guide attempts to help teachers of American Indian children in grades 4-6 provide a culturally relevant education that takes place in the regular classroom, includes content related to Indian students' lives, makes students proud, expands to other experiences, and enhances learning. Creating sacred places means responding appropriately to…

  19. Creating Sacred Places for Students in Grades 9-12.

    ERIC Educational Resources Information Center

    Fox, Sandra J.

    This guide attempts to help teachers of American Indian students in grades 9-12 provide a culturally relevant education that takes place in the regular classroom, includes content related to Indian students' lives, makes students proud, expands to other experiences, and enhances learning. Creating sacred places means responding appropriately to…

  20. Creating Sacred Places for Students in Grades 7&8.

    ERIC Educational Resources Information Center

    Fox, Sandra J.

    This guide attempts to help teachers of American Indian students in grades 7-8 provide a culturally relevant education that takes place in the regular classroom, includes content related to Indian students' lives, makes students proud, expands to other experiences, and enhances learning. Creating sacred places means responding appropriately to…

  1. Places to Live: Important Dimensions in Child Care Settings

    ERIC Educational Resources Information Center

    Greenman, Jim

    2007-01-01

    Child care centers can be great institutions of learning and caring, if everyone pays attention to some important dimensions that also make them reasonable places to live. Children need a place where they have full use of their bodies and senses and enough freedom to take advantage of the variety of life, where they can find or invent the spaces…

  2. Apply an Augmented Reality in a Mobile Guidance to Increase Sense of Place for Heritage Places

    ERIC Educational Resources Information Center

    Chang, Yu-Lien; Hou, Huei-Tse; Pan, Chao-Yang; Sung, Yao-Ting; Chang, Kuo-En

    2015-01-01

    Based on the sense of place theory and the design principles of guidance and interpretation, this study developed an augmented reality mobile guidance system that used a historical geo-context-embedded visiting strategy. This tool for heritage guidance and educational activities enhanced visitor sense of place. This study consisted of 3 visitor…

  3. An analytical method about anomalies on the synthetical variables of the multiple seismic activity parameters-taking 2 M =7 earthquakes occurring in Qinghai as examples

    NASA Astrophysics Data System (ADS)

    Ma, Heqing; Yang, Mingzhi

    2014-05-01

    Based on the random field theory, a new method of the synthetical variables of the multiple seismic activity parameters has been proposed. This method is that the natural perpendicular function development has been used on the random field function of seismic activity first. And then the synthetical variables constituted of the linear combination of four seismic activity parameters, i.e. the seismic strain release E-, the average distance between each two earthquakes D, the average time interval between each two earthquakes T , and the earthquake occurrence rate N have been studied. Though the analysis on the synthetical variables about the field, the seismic activity anomalies before large earthquakes have been drew. As the examples, the Gonghe M=7.0 earthquake occurred in Qinghai, 1990 and the Yushu M=7.1 earthquake occurred in Qinghai, 2010 have been discussed. The results have showed that before the two M=7 earthquakes, the main synthetical variables have all showed obvious abnormal variations, displaying better corresponding relationship with these two earthquakes. The synthetical variables of seismic activity field can focus on the slight differences which are included in each original variable. And the abnormal variations showed from the synthetical variables are as obvious as possible. The authors think that the synthetical variable method is possibly an effective analytic technique. Key words: seismic activity field; natural perpendicular function development; synthetical variables; anomaly; Earthquake example

  4. Taking a Broader View

    ERIC Educational Resources Information Center

    Flannery, Maura C.

    2005-01-01

    A study on stem cells is presented by understanding the environment in which they are found, the support cells and blood vessels as well as the protein scaffolds and other molecules. Researchers found that stem cells in reproductive tissue are surrounded by a pocket of support cells that hold them in place and align them to divide properly, so…

  5. When perspective taking increases taking: reactive egoism in social interaction.

    PubMed

    Epley, Nicholas; Caruso, Eugene; Bazerman, Max H

    2006-11-01

    Group members often reason egocentrically, believing that they deserve more than their fair share of group resources. Leading people to consider other members' thoughts and perspectives can reduce these egocentric (self-centered) judgments such that people claim that it is fair for them to take less; however, the consideration of others' thoughts and perspectives actually increases egoistic (selfish) behavior such that people actually take more of available resources. A series of experiments demonstrates this pattern in competitive contexts in which considering others' perspectives activates egoistic theories of their likely behavior, leading people to counter by behaving more egoistically themselves. This reactive egoism is attenuated in cooperative contexts. Discussion focuses on the implications of reactive egoism in social interaction and on strategies for alleviating its potentially deleterious effects. PMID:17059307

  6. Calculation of activation energies for transport and recombination in mesoporous TiO2/dye/electrolyte films--taking into account surface charge shifts with temperature.

    PubMed

    O'Regan, Brian C; Durrant, James R

    2006-05-01

    Transient photovoltage and photocurrent measurements have been employed to determine the recombination and transport kinetics in operating dye-sensitized photovoltaic cells as a function of potential and temperature. Photocurrent transients have been taken at the open circuit potential, as opposed to the standard measurement at short circuit. Kinetic results have been used to calculate the activation energy as function of the Fermi level position in the TiO(2). In the calculation of activation energies, we have explicitly taken into account the temperature dependence of the offset between the electrolyte redox potential and the conduction band edge. This new method gives activation energies that decrease linearly as the Fermi level position moves toward the conduction band edge, as expected, but not found in previous studies. The results are consistent with the presence of a distribution of traps below the TiO(2) conduction band, the detrapping from which limits both the transport and the recombination of electrons. PMID:16640403

  7. Teachers Taking Professional Abuse

    ERIC Educational Resources Information Center

    Normore, Anthony H.; Floyd, Andrea

    2005-01-01

    Preservice teachers get their first teaching position hoping to take the first step toward becoming professional educators and expecting support from experienced colleagues and administrators, who often serve as their mentors. In this article, the authors present the story of Kristine (a pseudonym), who works at a middle school in a large U.S.…

  8. Take a Bow

    ERIC Educational Resources Information Center

    Spitzer, Greg; Ogurek, Douglas J.

    2009-01-01

    Performing-arts centers can provide benefits at the high school and collegiate levels, and administrators can take steps now to get the show started. When a new performing-arts center comes to town, local businesses profit. Events and performances draw visitors to the community. Ideally, a performing-arts center will play many roles: entertainment…

  9. Take time for laughter.

    PubMed

    Huntley, Mary I

    2009-01-01

    Taking time for positive laughter in the workplace every day is energizing, health-promoting, and rewarding. Humor happenings and mirthful moments are all around us; we need to be receptive to them. Research provides evidence that laughter is a powerful tool when used appropriately in our personal and professional life journey. PMID:19343850

  10. Simulating Price-Taking

    ERIC Educational Resources Information Center

    Engelhardt, Lucas M.

    2015-01-01

    In this article, the author presents a price-takers' market simulation geared toward principles-level students. This simulation demonstrates that price-taking behavior is a natural result of the conditions that create perfect competition. In trials, there is a significant degree of price convergence in just three or four rounds. Students find this…

  11. Take action: influence diversity.

    PubMed

    Gomez, Norma J

    2013-01-01

    Increased diversity brings strength to nursing and ANNA. Being a more diverse association will require all of us working together. There is an old proverb that says: "one hand cannot cover the sky; it takes many hands." ANNA needs every one of its members to be a part of the diversity initiative. PMID:24579394

  12. Taking the thrombin "fork".

    PubMed

    Mann, Kenneth G

    2010-07-01

    The proverb that probably best exemplifies my career in research is attributable to Yogi Berra (http://www.yogiberra.com/), ie, "when you come to a fork in the road ... take it." My career is a consequence of chance interactions with great mentors and talented students and the opportunities provided by a succession of ground-breaking improvements in technology. PMID:20554951

  13. Taking Library Leadership Personally

    ERIC Educational Resources Information Center

    Davis, Heather; Macauley, Peter

    2011-01-01

    This paper outlines the emerging trends for leadership in the knowledge era. It discusses these within the context of leading, creating and sustaining the performance development cultures that libraries require. The first step is to recognise that we all need to take leadership personally no matter whether we see ourselves as leaders or followers.…

  14. A Critical Pedagogy of Place and the Critical Place(s) of Pedagogy

    ERIC Educational Resources Information Center

    Stevenson, Robert B.

    2008-01-01

    The notion of place-based education as grounding student learning in the local raises important questions about what constitutes the "local" in a now closely interconnected world and what constitutes an educational "place" when places of learning are shifting, as both new virtual sites emerge and old physical ones, including schools, lose some of…

  15. The Process and Pitfalls of Developing a Culturally Relevant Curriculum To Reduce AIDS among Sexually Active Teenagers: The Take 5 Project.

    ERIC Educational Resources Information Center

    Gillmore, Mary R.; And Others

    Several studies have shown that adolescents have reasonably high levels of knowledge about Acquired Immune Deficiency Syndrome (AIDS) transmission and prevention, yet they still engage in risky sexual activities. In response to this dilemma, a theoretically and empirically grounded intervention which went beyond presenting facts and figures was…

  16. Crowdsourcing a Collective Sense of Place

    PubMed Central

    Jenkins, Andrew; Croitoru, Arie; Crooks, Andrew T.; Stefanidis, Anthony

    2016-01-01

    Place can be generally defined as a location that has been assigned meaning through human experience, and as such it is of multidisciplinary scientific interest. Up to this point place has been studied primarily within the context of social sciences as a theoretical construct. The availability of large amounts of user-generated content, e.g. in the form of social media feeds or Wikipedia contributions, allows us for the first time to computationally analyze and quantify the shared meaning of place. By aggregating references to human activities within urban spaces we can observe the emergence of unique themes that characterize different locations, thus identifying places through their discernible sociocultural signatures. In this paper we present results from a novel quantitative approach to derive such sociocultural signatures from Twitter contributions and also from corresponding Wikipedia entries. By contrasting the two we show how particular thematic characteristics of places (referred to herein as platial themes) are emerging from such crowd-contributed content, allowing us to observe the meaning that the general public, either individually or collectively, is assigning to specific locations. Our approach leverages probabilistic topic modelling, semantic association, and spatial clustering to find locations are conveying a collective sense of place. Deriving and quantifying such meaning allows us to observe how people transform a location to a place and shape its characteristics. PMID:27050432

  17. Crowdsourcing a Collective Sense of Place.

    PubMed

    Jenkins, Andrew; Croitoru, Arie; Crooks, Andrew T; Stefanidis, Anthony

    2016-01-01

    Place can be generally defined as a location that has been assigned meaning through human experience, and as such it is of multidisciplinary scientific interest. Up to this point place has been studied primarily within the context of social sciences as a theoretical construct. The availability of large amounts of user-generated content, e.g. in the form of social media feeds or Wikipedia contributions, allows us for the first time to computationally analyze and quantify the shared meaning of place. By aggregating references to human activities within urban spaces we can observe the emergence of unique themes that characterize different locations, thus identifying places through their discernible sociocultural signatures. In this paper we present results from a novel quantitative approach to derive such sociocultural signatures from Twitter contributions and also from corresponding Wikipedia entries. By contrasting the two we show how particular thematic characteristics of places (referred to herein as platial themes) are emerging from such crowd-contributed content, allowing us to observe the meaning that the general public, either individually or collectively, is assigning to specific locations. Our approach leverages probabilistic topic modelling, semantic association, and spatial clustering to find locations are conveying a collective sense of place. Deriving and quantifying such meaning allows us to observe how people transform a location to a place and shape its characteristics. PMID:27050432

  18. Place Cells, Grid Cells, Attractors, and Remapping

    PubMed Central

    Jeffery, Kathryn J.

    2011-01-01

    Place and grid cells are thought to use a mixture of external sensory information and internal attractor dynamics to organize their activity. Attractor dynamics may explain both why neurons react coherently following sufficiently large changes to the environment (discrete attractors) and how firing patterns move smoothly from one representation to the next as an animal moves through space (continuous attractors). However, some features of place cell behavior, such as the sometimes independent responsiveness of place cells to environmental change (called “remapping”), seem hard to reconcile with attractor dynamics. This paper suggests that the explanation may be found in an anatomical separation of the two attractor systems coupled with a dynamic contextual modulation of the connection matrix between the two systems, with new learning being back-propagated into the matrix. Such a scheme could explain how place cells sometimes behave coherently and sometimes independently. PMID:22135756

  19. Case study of McCormick place cogeneration project

    SciTech Connect

    Overstreet, E.L.

    1994-12-31

    In the authors business of providing district energy services, competition is the key to his being able to have a positive impact on the environment, business stability, and economic activity. In the district energy industry, the competitive options are for property owners to continue to self generate energy to meet their needs, purchase energy from a company that utilizes electricity during off-peak hours to produce chilled water or take advantage of a total solution of purchasing tri-generation energy from Trigen-Peoples District Energy Company. Tri-generation is an innovative technology which involves the simultaneous production of steam, chilled water, and electricity. The McCormick Place cogeneration project calls for producing steam and chilled water (co-) for use by the Metropolitan Pier and Exposition Authority (MPEA). The plant will produce electricity (tri-) to run the production equipment.

  20. Auditory perspective taking.

    PubMed

    Martinson, Eric; Brock, Derek

    2013-06-01

    Effective communication with a mobile robot using speech is a difficult problem even when you can control the auditory scene. Robot self-noise or ego noise, echoes and reverberation, and human interference are all common sources of decreased intelligibility. Moreover, in real-world settings, these problems are routinely aggravated by a variety of sources of background noise. Military scenarios can be punctuated by high decibel noise from materiel and weaponry that would easily overwhelm a robot's normal speaking volume. Moreover, in nonmilitary settings, fans, computers, alarms, and transportation noise can cause enough interference to make a traditional speech interface unusable. This work presents and evaluates a prototype robotic interface that uses perspective taking to estimate the effectiveness of its own speech presentation and takes steps to improve intelligibility for human listeners. PMID:23096077

  1. Teach Kids Test-Taking Tactics

    ERIC Educational Resources Information Center

    Glenn, Robert E.

    2004-01-01

    Teachers can do something to help ensure students will do better on tests. They can actively teach test-taking skills so pupils will be better armed in the battle to acquire knowledge. The author challenges teachers to use the suggestions provided in this article in the classroom, and to share them with their students. Test-taking strategies will…

  2. Take the "C" Train

    ERIC Educational Resources Information Center

    Lawton, Rebecca

    2008-01-01

    In this essay, the author recalls several of her experiences in which she successfully pulled her boats out of river holes by throwing herself to the water as a sea-anchor. She learned this trick from her senior guides at a spring training. Her guides told her, "When you're stuck in a hole, take the "C" train."" "Meaning?" The author asked her…

  3. Cooperative Ecology & Place: Development of a Pedagogy of Place Curriculum.

    ERIC Educational Resources Information Center

    Lewicki, James

    The major tenets of a pedagogy of place are that nature teaches; understanding place is indispensable to community; where and how a student learns is as vital as what a student learns; and respect is integral to learning. Environmental literacy is the capacity to perceive and interpret the relative health of environmental systems and to take…

  4. When a Child Has Difficulty Moving from Place to Place

    ERIC Educational Resources Information Center

    Greenspan, Stanley I.

    2007-01-01

    In this article, the author responds to a teacher's request for an advice on how to help a 5-year-old child in her class who has difficulty moving from place to place. The author states that the child has a problem on processing information and sensations that have to do with what he sees. This is called "visual-spatial processing" or…

  5. Take Your Class Outdoors.

    ERIC Educational Resources Information Center

    Shellenberger, Barbara R.

    1981-01-01

    Offers suggestions for designing outdoor activities to provide students with opportunities for exploring, observing, and discovering. Outlines several science activities for each of the following topics: trees, rocks, soil, insects, wild flowers, grasses, lichens, and clouds. (DS)

  6. Taking Care of Yourself

    MedlinePlus

    ... of moderate-intensity physical activity (brisk walking, jogging, cycling, etc.) at least 3 to 4 days per ... of moderate-intensity physical activity (brisk walking, jogging, cycling, etc.) at least 3 to 4 days per ...

  7. China takes an active role in combating an Ebola outbreak: On-site observations and reflections from a Chinese healthcare provider

    PubMed Central

    Lu, Hongzhou

    2015-01-01

    Summary As one of the active participants in the global fight against the 2014 outbreak of Ebola virus disease (EVD) in West Africa, China supplied many resources, including medical experts and scientists as well as medical supplies, to the affected countries. A member of the first contingent of Chinese public health experts who worked in Sierra Leone for 65 days, I am pleased to have this opportunity to review the major work done by our team to help deal with the Ebola epidemic in Sierra Leone. This is the first time that a Chinese public health training team has worked in West Africa. The team provides trainings for people from local communities in an effort to encourage local residents to get involved in the war against Ebola. However, the implementation of active measures against Ebola in West Africa was hampered somewhat by certain drawbacks in the area in terms of the health system, the shortage of medical resources, the high illiteracy rate, unhealthy lifestyles, and traditional funeral rites. All of these aspects need to be gradually improved in the aftermath of Ebola, and I believe that this is an area in which the Chinese public health system can play an important role. PMID:26668785

  8. Factors Associated with Participation, Active Refusals and Reasons for Not Taking Part in a Mortality Followback Survey Evaluating End-of-Life Care

    PubMed Central

    Calanzani, Natalia; Higginson, Irene J; Koffman, Jonathan; Gomes, Barbara

    2016-01-01

    Background Examination of factors independently associated with participation in mortality followback surveys is rare, even though these surveys are frequently used to evaluate end-of-life care. We aimed to identify factors associated with 1) participation versus non-participation and 2) provision of an active refusal versus a silent refusal; and systematically examine reasons for refusal in a population-based mortality followback survey. Methods Postal survey about the end-of-life care received by 1516 people who died from cancer (aged ≥18), identified through death registrations in London, England (response rate 39.3%). The informant of death (a relative in 95.3% of cases) was contacted 4–10 months after the patient died. We used multivariate logistic regression to identify factors associated with participation/active refusals and content analysis to examine refusal reasons provided by 205 nonparticipants. Findings The odds of partaking were higher for patients aged 90+ (AOR 3.48, 95%CI: 1.52–8.00, ref: 20–49yrs) and female informants (AOR 1.70, 95%CI: 1.33–2.16). Odds were lower for hospital deaths (AOR 0.62, 95%CI: 0.46–0.84, ref: home) and proxies other than spouses/partners (AORs 0.28 to 0.57). Proxies of patients born overseas were less likely to provide an active refusal (AOR 0.49; 95% CI: 0.32–0.77). Refusal reasons were often multidimensional, most commonly study-related (36.0%), proxy-related and grief-related (25.1% each). One limitation of this analysis is the large number of nonparticipants who did not provide reasons for refusal (715/920). Conclusions Our survey better reached proxies of older patients while those dying in hospitals were underrepresented. Proxy characteristics played a role, with higher participation from women and spouses/partners. More information is needed about the care received by underrepresented groups. Study design improvements may guide future questionnaire development and help develop strategies to increase

  9. Venturing into Scary Places: The Minority Experience

    ERIC Educational Resources Information Center

    Bennett, Craig

    2007-01-01

    Students who have lived as part of a majority for their entire life may find it frightening to be asked to visit a place where they will be in the minority. In this article, the author uses this assignment to demonstrate to his students how some people feel everyday. The Minority Experience assignment challenges students to actively participate in…

  10. Parentally Placed Private School Students with Disabilities

    ERIC Educational Resources Information Center

    Sopko, Kimberly M.

    2013-01-01

    This document focuses on state education agency (SEA) support for child find, consultation and provision of equitable service provisions for parentally placed private school students with disabilities. Project Forum at the National Association of State Directors of Special Education (NASDSE) completed this activity as part of its cooperative…

  11. What Kind of Place Is Secondary School?

    ERIC Educational Resources Information Center

    Hayes, Monie; Vivian, Craig

    2008-01-01

    Secondary school introduces students to a public space that differs from the private spaces commonly found in elementary schools. One of the markers signaling a transition from private to public space is the use of discourse. Secondary schools are places where social practices reject the democratic and caring activities found in the elementary…

  12. Identity as "knowing your place": the narrative construction of space in a healthcare profession.

    PubMed

    van Vuuren, Mark; Westerhof, Gerben J

    2015-03-01

    The construction of space in which a story takes place can have important consequences for the evaluation of health interventions. In this article, we explore the ways professionals narratively position themselves in a situation, treating identity literally as "knowing one's place." More specifically, we explore the spatial language health professionals use to describe their work. Using descriptions of professionals in a drug habilitation organization, we illustrate how they use route (i.e., an active tour through the space), survey (i.e., a stationary viewpoint from above), and gaze perspectives (i.e. a stable viewpoint onto a place) to explain the work situations they encounter. Each of these perspectives facilitates a different mode of evaluation in terms of distance, emotion, and identity. We propose opportunities for research and implications of the ways in which spaces and spatial perspectives set the scene in the narratives of healthcare professionals. PMID:25762387

  13. Physics Take-Outs

    NASA Astrophysics Data System (ADS)

    Riendeau, Diane; Hawkins, Stephanie; Beutlich, Scott

    2016-03-01

    Most teachers want students to think about their course content not only during class but also throughout their day. So, how do you get your students to see how what they learn in class applies to their lives outside of class? As physics teachers, we are fortunate that our students are continually surrounded by our content. How can we get them to notice the physics around them? How can we get them to make connections between the classroom content and their everyday lives? We would like to offer a few suggestions, Physics Take-Outs, to solve this problem.

  14. Place cells and place navigation

    PubMed Central

    Bures, J.; Fenton, A. A.; Kaminsky, Yu.; Zinyuk, L.

    1997-01-01

    The assumption that hippocampal place cells (PCs) form the neural substrate of cognitive maps can be experimentally tested by comparing the effect of experimental interventions on PC activity and place navigation. Conditions that interfere with place navigation (darkness, cholinergic blockade) but leave PC activity unaffected obviously disrupt spatial memory at a post-PC level. Situations creating a conflict between egocentric and allocentric orientation (place navigation in the Morris water maze filled with slowly rotating water) slow down spatial learning. PC recording in rats searching food pellets in a rotating arena makes it possible to determine which firing fields are stable relative to the room (allocentrically dependent on sighted extramaze landmarks), to the surface of the arena (dependent on egocentric path integration mechanisms and intra-arena cues), or disappear during rotation. Such comparison is made possible by the computerized tracking system simultaneously displaying a rat’s locomotion and the respective firing rate maps both in the room reference and arena reference frames. More severe conflict between allocentric and egocentric inputs is produced in the field clamp situation when the rat searching food in a ring-shaped arena is always returned by rotation of the arena to the same allocentric position. Ten-minute exposure to this condition caused subsequent disintegration or remapping of 70% PCs (n = 100). Simultaneous examination of PC activity and navigation is possible in the place avoidance task. A rat searching food in a stationary or rotating arena learns to avoid an allocentrically or egocentrically defined location where it receives mild electric footshock. In the place preference task the rat releases pellet delivery by entering an unmarked goal area and staying in it for a criterion time. Both tasks allow direct comparison of the spatial reference frames used by the PCs and by the behaving animal. PMID:8990211

  15. Taking a Pulse on Your Practice.

    PubMed

    Hoagland-Smith, Leanne

    2015-01-01

    Each medical practice, like a living organism, occasionally requires reading of its vital signs. As with human beings, one of those vital signs is the pulse. For your medical practice, just like your patients, there are numerous places from which to take that reading. This article reviews seven key pulses that provide insight into what is happening within the workplace culture of your practice. PMID:26856032

  16. [Which place for physicians in blood supply?].

    PubMed

    Danic, B; Pelletier, B

    2013-05-01

    Historically, blood transfusion has been divised, enhanced and organized by physicians. The special status of blood led to ensure that collection of blood and its components were placed under the supervision of a physician. Throughout its history, blood transfusion organization in France has established an exclusive exercise of the collection of blood and its components entrusted to doctors, thus creating the concept of "medicine of donation". This view is changing, and programmed exercise of this activity by nurses led to question about this profession perimeter, its necessary evolution, and finally about the place of physicians in blood supply. PMID:23537956

  17. Cluster II quartet take the stage together

    NASA Astrophysics Data System (ADS)

    1999-11-01

    prime contractor Dornier Satellitensysteme. On completion, they were sent to IABG in Ottobrunn, near Munich, for intensive vibration, thermal, vacuum and magnetic testing. The European ground segment for the mission is just as important. A vast amount of data - equivalent to 290 million printed pages - will be returned to Earth over the mission's two-year lifetime. Signals to and from the spacecraft will be sent via a 15 metre antenna at Villafranca in Spain and processed at the European Space Operations Centre (ESOC) at Darmstadt, Germany. The main control room at ESOC will be used during the launch and early phases of the mission, with teams of operators working round the clock. About two weeks after the second Cluster II pair are placed in their operational orbits, mission operations will switch to a smaller, dedicated control room at ESOC. The Joint Science Operations Centre at Rutherford Appleton Laboratory in the UK will co-ordinate the scientific investigations. Its main task will be to combine all requirements from the 11 science instrument teams into an overall plan. The flow of information returned by the 44 instruments will be distributed to eight national data centres, six in Europe, one in the USA and the other in China. Solar Maximum Cluster II is part of an international programme to find out more about how the Sun influences the Earth. The four Cluster II satellites will join an armada of spacecraft from many countries, which are already studying the Sun and high speed wind of charged particles (mainly electrons and protons) which it continually blasts into space. Ulysses and SOHO, both joint ESA-NASA missions, and ESA's Cluster II , when it will be there, are the flagships of this armada. The timing of the mission is ideal, since it will take place during a period of peak activity in the Sun's 11-year cycle, when sunspots and solar radiation reach a maximum. Cluster II will measure the effects of this activity on near-Earth space as incoming energetic

  18. Taking the Plunge.

    ERIC Educational Resources Information Center

    Hatch, Stanley

    1987-01-01

    Describes why lake hikes practiced at Girl Scout Camp Bonnie Brae (Massachusetts) are an ideal camp activity to teach aquatic ecology and engage the senses. Discusses program benefits: camper/counselor interaction, personal and group challenge, and conflict resolution. (NEC)

  19. Taking Center Stage.

    ERIC Educational Resources Information Center

    Cohen, Andrew

    1995-01-01

    Describes Ohio's 390,000 square-foot Perry High School and Community Fitness Center and its ability to accommodate all segments of both school and community group activities. A list of companies that supply the center is included. (GR)

  20. D/93 place robotic simulation

    SciTech Connect

    Reeves, T.

    1990-11-01

    This paper describes the PLACE (Positioner Layout and Cell Evaluator) system from McDonnell Douglas being used to lay out, evaluate, and off-line program the Hiperco 50 machining work cell. The PLACE system allows the user to evaluate manufacturing cells with various combinations of robots and cell design to arrive at the best workable solution to a cell design problem. The PLACE system simulation of the Hiperco 50 machining work cell includes two machine tools, various Q stations, quick-change robot tooling and an ASEA IRB6L 5-axis robot. By using the PLACE system, it has been possible to determine the optimal location for positioning each component within the work cell.

  1. Place recognition using batlike sonar.

    PubMed

    Vanderelst, Dieter; Steckel, Jan; Boen, Andre; Peremans, Herbert; Holderied, Marc W

    2016-01-01

    Echolocating bats have excellent spatial memory and are able to navigate to salient locations using bio-sonar. Navigating and route-following require animals to recognize places. Currently, it is mostly unknown how bats recognize places using echolocation. In this paper, we propose template based place recognition might underlie sonar-based navigation in bats. Under this hypothesis, bats recognize places by remembering their echo signature - rather than their 3D layout. Using a large body of ensonification data collected in three different habitats, we test the viability of this hypothesis assessing two critical properties of the proposed echo signatures: (1) they can be uniquely classified and (2) they vary continuously across space. Based on the results presented, we conclude that the proposed echo signatures satisfy both criteria. We discuss how these two properties of the echo signatures can support navigation and building a cognitive map. PMID:27481189

  2. There's No Place Like Home

    MedlinePlus

    ... Navigation Bar Home Current Issue Past Issues Feature: Senior Living There's No Place Like Home Past Issues / ... state offices on aging; social services organizations; nearby senior centers; and civic, tribal, and religious organizations. They ...

  3. Letting Thoughts Take Wing

    NASA Technical Reports Server (NTRS)

    Jorgensen, Chuck; Wheeler, Kevin

    2002-01-01

    Scientists are conducting research into electroencephalograms (EEGs) of brainwave activity, and electromyography (EMG) of muscle activity, in order to develop systems which can control an aircraft with only a pilot's thoughts. This article describes some EEG and EMG signals, and how they might be analyzed and interpreted to operate an aircraft. The development of a system to detect and interpret fine muscle movements is also profiled in the article.

  4. Microgravity Smoldering Combustion Takes Flight

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The Microgravity Smoldering Combustion (MSC) experiment lifted off aboard the Space Shuttle Endeavour in September 1995 on the STS-69 mission. This experiment is part of series of studies focused on the smolder characteristics of porous, combustible materials in a microgravity environment. Smoldering is a nonflaming form of combustion that takes place in the interior of combustible materials. Common examples of smoldering are nonflaming embers, charcoal briquettes, and cigarettes. The objective of the study is to provide a better understanding of the controlling mechanisms of smoldering, both in microgravity and Earth gravity. As with other forms of combustion, gravity affects the availability of air and the transport of heat, and therefore, the rate of combustion. Results of the microgravity experiments will be compared with identical experiments carried out in Earth's gravity. They also will be used to verify present theories of smoldering combustion and will provide new insights into the process of smoldering combustion, enhancing our fundamental understanding of this frequently encountered combustion process and guiding improvement in fire safety practices.

  5. Why It Takes Prevention, Not Detection, to Fight Bioterrorism

    ERIC Educational Resources Information Center

    Janata, Jiri (Art)

    2005-01-01

    Following the events which took place on September 11, 2001, and the anthrax attacks which occurred after that date, US authorities became concerned with the idea that an assault with chemical or biological weapons could take place on American territory or in American ships or planes. A worrisome model for such an assault was the 1995 terrorist…

  6. Correlates of Intellectual Risk Taking in Elementary School Science

    ERIC Educational Resources Information Center

    Beghetto, Ronald A.

    2009-01-01

    This study had the goal of exploring factors associated with elementary students' (N = 585) reports of intellectual risk taking in science. Intellectual risk taking (IRT) was defined as engaging in adaptive learning behaviors (sharing tentative ideas, asking questions, attempting to do and learn new things) that placed the learner at risk of…

  7. Nursing Research--Taking an Active Interest.

    ERIC Educational Resources Information Center

    Cleverly, Dankay

    1998-01-01

    In Britain, nurses' attitudes toward research are changing. Schools of nursing must consider the following research issues: funding, contracts, support, publication, and staff recruitment and retention. (SK)

  8. Take My Kids, Pleeze!

    ERIC Educational Resources Information Center

    Bushweller, Kevin

    1996-01-01

    Increasing numbers of parents are "dumping" parental responsibilities at the school-house door. However, a highly vocal and politically active minority of parents are demanding that schools relinquish those responsibilities. One helpful role the schools can play is to offer parent-education classes that provide specific tips on disciplining…

  9. Does Taking Photographs Help?

    ERIC Educational Resources Information Center

    Hand, Sarah

    2010-01-01

    Since many people tend to use photographs as memory anchors, this author decided she wanted to know whether the process of capturing and manipulating an image taken during a learning activity would act as a memory anchor for children's visual, auditory and kinaesthetic memories linked to their cognitive learning at the time. In plain English,…

  10. Taking Student Government Seriously.

    ERIC Educational Resources Information Center

    Bolen, J. R.

    1999-01-01

    Discusses the student government at La Mesa Middle School (California) that was modeled after the three-branch U.S. government as a means for increasing students' civic understanding. Describes the structure of the legislative, judicial, and executive branches, the different activities of the student government, and the reasons for the hiatus.…

  11. Take Math Outdoors.

    ERIC Educational Resources Information Center

    Schall, William E.

    1984-01-01

    Scavenger hunts, collecting bottle caps, observing shadows, and other outdoor activities can be developed into a mathematics unit that motivates students to acquire basic mathematical skills. A variety of natural ways to collect data are offered to help foster learning. (DF)

  12. Take a Planet Walk

    ERIC Educational Resources Information Center

    Schuster, Dwight

    2008-01-01

    Physical models in the classroom "cannot be expected to represent the full-scale phenomenon with complete accuracy, not even in the limited set of characteristics being studied" (AAAS 1990). Therefore, by modifying a popular classroom activity called a "planet walk," teachers can explore upper elementary students' current understandings; create an…

  13. 50 CFR 216.152 - Permissible methods of taking.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND IMPORTING OF MARINE MAMMALS Taking Of Marine Mammals Incidental To Missile Launch Activities from San Nicolas Island, CA § 216..., take marine mammals by harassment, within the area described in § 216.150, provided the activity is...

  14. The Path Is Place: Skateboarding, Graffiti and Performances of Place

    ERIC Educational Resources Information Center

    Ong, Adelina

    2016-01-01

    This article reflects on two performances of place involving graffiti and skateboarding: the first looks at a graffiti intervention by SKL0, an urban artist in Singapore, and the second examines the "Long Live Southbank" ("LLSB") campaign to resist the relocation of Southbank's Undercroft, an appropriated skate space in London.…

  15. Modeling of the Process of Welding Aerosol Formation Taking Place During Mining Equipment Fabrication

    NASA Astrophysics Data System (ADS)

    Grishagin, V. M.; Filonov, A. V.; Kiselev, S. V.

    2016-04-01

    In the paper the authors formulate the thermodynamic model of welding aerosol formation. The thermodynamic parameters of chemical compounds and aerosol phases are calculated. The authors develop a program for numerical calculation of various elements emission under varied parameters changing the welding conditions.

  16. The Eclipsing Binary Di Herculis: One Mystery Solved, But Another Takes Its Place

    NASA Astrophysics Data System (ADS)

    Zimmerman, Nicole; Guinan, E.; Maloney, F.

    2010-01-01

    The 8th-mag eclipsing binary DI Herculis has perplexed scientists for the past few decades due to its anomalously slow apsidal motion rate. DI Her consists of two main-sequence stars (B5V, B6V), with P(orb) = 10.55 days, and eccentricity(e= 0.489). Since the apsidal motion is dominated by General Relativity, the system is one of the few tests available for verifying the theory. Combining the expected classical (1.93°/100 yr) and relativistic (2.34°/100 yr) effects, the predicted apsidal motion rate is 4.27°/100 yr. Our recent determination of the apsidal motion yields 1.33°+/-0.25 /100 yr, based on eclipse timings from 1936-2008. Recently, Albrecht et al (2009, Nature 461) have apparently solved the apsidal motion anomaly of DI Her, finding that the axes of both stars are significantly inclined from the normal to the orbital plane. This was determined from the radial velocity curves and observing the Rossiter-McLaughlin effect during primary and secondary eclipses. Having significantly misaligned axes of rotation produces a perturbation that greatly reduces the classical apsidal motion effect, thus explaining the observed small apsidal motion rate. Even though this discovery apparently solves the problem, it raises new questions as to how the axes are so tilted. Additionally, tilted axes are expected to contribute to other orbital effects, such as changes in orbital inclination, which have not yet observed from the apparent constancy in eclipse depths over time. We have also searched for evidence of small periodic oscillations in the eclipse timings and found no evidence of a light travel time effect arising from a possible tertiary component. Further, we find evidence that the projected rotation axes of the stars may be precessing, since it appears that the value of V(rot)sini has increased over the past 30 years. This research was supported by NSF/RUI Grants AST05-07536/42.

  17. Where Does the Transformation of Precipitated Ceria Nanoparticles in Hydroponic Plants Take Place?

    PubMed

    Ma, Yuhui; Zhang, Peng; Zhang, Zhiyong; He, Xiao; Zhang, Junzhe; Ding, Yayun; Zhang, Jing; Zheng, Lirong; Guo, Zhi; Zhang, Lijuan; Chai, Zhifang; Zhao, Yuliang

    2015-09-01

    Cerium oxide nanoparticles (CeO2 NPs) have been found to be partly biotransformed from Ce(IV) to Ce(III) in plants, yet the transformation process and mechanism are not fully understood. Here, we try to clarify the specific site and necessary conditions for the transformation of precipitated CeO2 NPs in hydroponic cucumber plants. Three different treatment modes were adopted according to whether the NPs were incubated with roots all the time or not. Results showed that exposure modes significantly affect the translocation and transformation of CeO2 NPs. In the normal exposure mode, Ce was present as a Ce(IV) and Ce(III) mixture in the roots and shoots, and the proportion of Ce(III) in the shoots was enhanced obviously with the increase of exposure time. The results of short-time incubation and petiole exposure modes suggested that CeO2 NPs could not be reduced within a short incubation time (3 h) or be further reduced inside the plant tissues. It was deduced that root surfaces are the sites, and the physicochemical interaction between the NPs and root exudates at the nanobio interface is the necessary condition for the transformation of CeO2 NPs in plant systems. These results will contribute to understanding the transformation mechanism of CeO2 and other metal-based NPs and properly evaluate their ecological effects. PMID:26237071

  18. In what time scale proton transfer takes place in a live CHO cell?

    NASA Astrophysics Data System (ADS)

    Mojumdar, Supratik Sen; Chowdhury, Rajdeep; Mandal, Amit Kumar; Bhattacharyya, Kankan

    2013-06-01

    Excited state proton transfer (ESPT) of pyranine (8-hydroxypyrene-1,3,6-trisulfonate, HPTS) in a live Chinese hamster ovary (CHO) cell is studied by time resolved confocal microscopy. The cytoplasm region of the cell is stained by a photoacid, HPTS (HA). The time constant of initial proton transfer (τPT) in the cell is found to be ˜10 times longer than that in bulk water, while the time constants of recombination (τrec) and dissociation (τdiss) in the cell are ˜3 times and ˜2 times longer, respectively. The slower rate of proton transfer (˜10 times) inside the CHO cell compared to that in bulk water is ascribed to slower solvation dynamics, lower availability of free water molecules, and disruption of hydrogen-bond network inside the cell. Translational and rotational diffusion of HPTS inside a single CHO cell have been investigated by fluorescence correlation spectroscopy (FCS) and picosecond anisotropy measurement, respectively. Both the translational and rotational diffusion slow down inside the live cell. FCS studies indicate that HPTS remains tightly bound to a macromolecule inside the cell.

  19. A Reaction that Takes Place in Beakers but not in Conical Flasks

    ERIC Educational Resources Information Center

    White, Colin; Ophardt, Charles

    2004-01-01

    Inductors are substances that undergo a reaction and in so doing markedly accelerate or induce a simultaneous reaction. An experiment showing a reaction involving the oxidation of iodide to iodine by chromium (VI) found to be slow in the absence of acid, but which proceeded rapidly when iron (II) was induced is demonstrated.

  20. When Private Schools Take Public Dollars: What's the Place of Accountability in School Voucher Programs?

    ERIC Educational Resources Information Center

    Finn, Chester E., Jr.; Hentges, Christina M.; Petrilli, Michael J.; Winkler, Amber M.

    2009-01-01

    Critics of school voucher programs argue that private schools that receive taxpayer dollars should be held accountable to the same standards as public schools. School choice supporters counter that private schools should be left alone to answer to the parents of their students. The authors advocate for a re-visit to the discussion of…