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Sample records for active pixel image

  1. CMOS Active-Pixel Image Sensor With Simple Floating Gates

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R.; Nakamura, Junichi; Kemeny, Sabrina E.

    1996-01-01

    Experimental complementary metal-oxide/semiconductor (CMOS) active-pixel image sensor integrated circuit features simple floating-gate structure, with metal-oxide/semiconductor field-effect transistor (MOSFET) as active circuit element in each pixel. Provides flexibility of readout modes, no kTC noise, and relatively simple structure suitable for high-density arrays. Features desirable for "smart sensor" applications.

  2. A CMOS Energy Harvesting and Imaging (EHI) Active Pixel Sensor (APS) Imager for Retinal Prosthesis.

    PubMed

    Ay, S U

    2011-12-01

    A CMOS image sensor capable of imaging and energy harvesting on same focal plane is presented for retinal prosthesis. The energy harvesting and imaging (EHI) active pixel sensor (APS) imager was designed, fabricated, and tested in a standard 0.5 μm CMOS process. It has 54 × 50 array of 21 × 21 μm(2) EHI pixels, 10-bit supply boosted (SB) SAR ADC, and charge pump circuits consuming only 14.25 μW from 1.2 V and running at 7.4 frames per second. The supply boosting technique (SBT) is used in an analog signal chain of the EHI imager. Harvested solar energy on focal plane is stored on an off-chip capacitor with the help of a charge pump circuit with better than 70% efficiency. Energy harvesting efficiency of the EHI pixel was measured at different light levels. It was 9.4% while producing 0.41 V open circuit voltage. The EHI imager delivers 3.35 μW of power was delivered to a resistive load at maximum power point operation. The measured pixel array figure of merit (FoM) was 1.32 pW/frame/pixel while imager figure of merit (iFoM) including whole chip power consumption was 696 fJ/pixel/code for the EHI imager.

  3. Evaluation of a single-pixel one-transistor active pixel sensor for fingerprint imaging

    NASA Astrophysics Data System (ADS)

    Xu, Man; Ou, Hai; Chen, Jun; Wang, Kai

    2015-08-01

    Since it first appeared in iPhone 5S in 2013, fingerprint identification (ID) has rapidly gained popularity among consumers. Current fingerprint-enabled smartphones unanimously consists of a discrete sensor to perform fingerprint ID. This architecture not only incurs higher material and manufacturing cost, but also provides only static identification and limited authentication. Hence as the demand for a thinner, lighter, and more secure handset grows, we propose a novel pixel architecture that is a photosensitive device embedded in a display pixel and detects the reflected light from the finger touch for high resolution, high fidelity and dynamic biometrics. To this purpose, an amorphous silicon (a-Si:H) dual-gate photo TFT working in both fingerprint-imaging mode and display-driving mode will be developed.

  4. Characteristics of Monolithically Integrated InGaAs Active Pixel Image Array

    NASA Technical Reports Server (NTRS)

    Kim, Q.; Cunningham, T. J.; Pain, B.; Lange, M. J.; Olsen, G. H.

    1999-01-01

    Switching and amplifying characteristics of a newly developed monolithic InGaAs Active Pixel Imager Array are presented. The sensor array is fabricated from InGaAs material epitaxially deposited on an InP substrate.

  5. X-ray imaging characterization of active edge silicon pixel sensors

    NASA Astrophysics Data System (ADS)

    Ponchut, C.; Ruat, M.; Kalliopuska, J.

    2014-05-01

    The aim of this work was the experimental characterization of edge effects in active-edge silicon pixel sensors, in the frame of X-ray pixel detectors developments for synchrotron experiments. We produced a set of active edge pixel sensors with 300 to 500 μm thickness, edge widths ranging from 100 μm to 150 μm, and n or p pixel contact types. The sensors with 256 × 256 pixels and 55 × 55 μm2 pixel pitch were then bump-bonded to Timepix readout chips for X-ray imaging measurements. The reduced edge widths makes the edge pixels more sensitive to the electrical field distribution at the sensor boundaries. We characterized this effect by mapping the spatial response of the sensor edges with a finely focused X-ray synchrotron beam. One of the samples showed a distortion-free response on all four edges, whereas others showed variable degrees of distortions extending at maximum to 300 micron from the sensor edge. An application of active edge pixel sensors to coherent diffraction imaging with synchrotron beams is described.

  6. Active-Pixel Image Sensor With Analog-To-Digital Converters

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R.; Mendis, Sunetra K.; Pain, Bedabrata; Nixon, Robert H.

    1995-01-01

    Proposed single-chip integrated-circuit image sensor contains 128 x 128 array of active pixel sensors at 50-micrometer pitch. Output terminals of all pixels in each given column connected to analog-to-digital (A/D) converter located at bottom of column. Pixels scanned in semiparallel fashion, one row at time; during time allocated to scanning row, outputs of all active pixel sensors in row fed to respective A/D converters. Design of chip based on complementary metal oxide semiconductor (CMOS) technology, and individual circuit elements fabricated according to 2-micrometer CMOS design rules. Active pixel sensors designed to operate at video rate of 30 frames/second, even at low light levels. A/D scheme based on first-order Sigma-Delta modulation.

  7. Active pixel imagers incorporating pixel-level amplifiers based on polycrystalline-silicon thin-film transistors.

    PubMed

    El-Mohri, Youcef; Antonuk, Larry E; Koniczek, Martin; Zhao, Qihua; Li, Yixin; Street, Robert A; Lu, Jeng-Ping

    2009-07-01

    Active matrix, flat-panel imagers (AMFPIs) employing a 2D matrix of a-Si addressing TFTs have become ubiquitous in many x-ray imaging applications due to their numerous advantages. However, under conditions of low exposures and/or high spatial resolution, their signal-to-noise performance is constrained by the modest system gain relative to the electronic additive noise. In this article, a strategy for overcoming this limitation through the incorporation of in-pixel amplification circuits, referred to as active pixel (AP) architectures, using polycrystalline-silicon (poly-Si) TFTs is reported. Compared to a-Si, poly-Si offers substantially higher mobilities, enabling higher TFT currents and the possibility of sophisticated AP designs based on both n- and p-channel TFTs. Three prototype indirect detection arrays employing poly-Si TFTs and a continuous a-Si photodiode structure were characterized. The prototypes consist of an array (PSI-1) that employs a pixel architecture with a single TFT, as well as two arrays (PSI-2 and PSI-3) that employ AP architectures based on three and five TFTs, respectively. While PSI-1 serves as a reference with a design similar to that of conventional AMFPI arrays, PSI-2 and PSI-3 incorporate additional in-pixel amplification circuitry. Compared to PSI-1, results of x-ray sensitivity demonstrate signal gains of approximately 10.7 and 20.9 for PSI-2 and PSI-3, respectively. These values are in reasonable agreement with design expectations, demonstrating that poly-Si AP circuits can be tailored to provide a desired level of signal gain. PSI-2 exhibits the same high levels of charge trapping as those observed for PSI-1 and other conventional arrays employing a continuous photodiode structure. For PSI-3, charge trapping was found to be significantly lower and largely independent of the bias voltage applied across the photodiode. MTF results indicate that the use of a continuous photodiode structure in PSI-1, PSI-2, and PSI-3 results in

  8. Active pixel imagers incorporating pixel-level amplifiers based on polycrystalline-silicon thin-film transistors

    PubMed Central

    El-Mohri, Youcef; Antonuk, Larry E.; Koniczek, Martin; Zhao, Qihua; Li, Yixin; Street, Robert A.; Lu, Jeng-Ping

    2009-01-01

    Active matrix, flat-panel imagers (AMFPIs) employing a 2D matrix of a-Si addressing TFTs have become ubiquitous in many x-ray imaging applications due to their numerous advantages. However, under conditions of low exposures and∕or high spatial resolution, their signal-to-noise performance is constrained by the modest system gain relative to the electronic additive noise. In this article, a strategy for overcoming this limitation through the incorporation of in-pixel amplification circuits, referred to as active pixel (AP) architectures, using polycrystalline-silicon (poly-Si) TFTs is reported. Compared to a-Si, poly-Si offers substantially higher mobilities, enabling higher TFT currents and the possibility of sophisticated AP designs based on both n- and p-channel TFTs. Three prototype indirect detection arrays employing poly-Si TFTs and a continuous a-Si photodiode structure were characterized. The prototypes consist of an array (PSI-1) that employs a pixel architecture with a single TFT, as well as two arrays (PSI-2 and PSI-3) that employ AP architectures based on three and five TFTs, respectively. While PSI-1 serves as a reference with a design similar to that of conventional AMFPI arrays, PSI-2 and PSI-3 incorporate additional in-pixel amplification circuitry. Compared to PSI-1, results of x-ray sensitivity demonstrate signal gains of ∼10.7 and 20.9 for PSI-2 and PSI-3, respectively. These values are in reasonable agreement with design expectations, demonstrating that poly-Si AP circuits can be tailored to provide a desired level of signal gain. PSI-2 exhibits the same high levels of charge trapping as those observed for PSI-1 and other conventional arrays employing a continuous photodiode structure. For PSI-3, charge trapping was found to be significantly lower and largely independent of the bias voltage applied across the photodiode. MTF results indicate that the use of a continuous photodiode structure in PSI-1, PSI-2, and PSI-3 results in optical fill

  9. Memory based active contour algorithm using pixel-level classified images for colon crypt segmentation.

    PubMed

    Cohen, Assaf; Rivlin, Ehud; Shimshoni, Ilan; Sabo, Edmond

    2015-07-01

    In this paper, we introduce a novel method for detection and segmentation of crypts in colon biopsies. Most of the approaches proposed in the literature try to segment the crypts using only the biopsy image without understanding the meaning of each pixel. The proposed method differs in that we segment the crypts using an automatically generated pixel-level classification image of the original biopsy image and handle the artifacts due to the sectioning process and variance in color, shape and size of the crypts. The biopsy image pixels are classified to nuclei, immune system, lumen, cytoplasm, stroma and goblet cells. The crypts are then segmented using a novel active contour approach, where the external force is determined by the semantics of each pixel and the model of the crypt. The active contour is applied for every lumen candidate detected using the pixel-level classification. Finally, a false positive crypt elimination process is performed to remove segmentation errors. This is done by measuring their adherence to the crypt model using the pixel level classification results. The method was tested on 54 biopsy images containing 4944 healthy and 2236 cancerous crypts, resulting in 87% detection of the crypts with 9% of false positive segments (segments that do not represent a crypt). The segmentation accuracy of the true positive segments is 96%.

  10. Fiber pixelated image database

    NASA Astrophysics Data System (ADS)

    Shinde, Anant; Perinchery, Sandeep Menon; Matham, Murukeshan Vadakke

    2016-08-01

    Imaging of physically inaccessible parts of the body such as the colon at micron-level resolution is highly important in diagnostic medical imaging. Though flexible endoscopes based on the imaging fiber bundle are used for such diagnostic procedures, their inherent honeycomb-like structure creates fiber pixelation effects. This impedes the observer from perceiving the information from an image captured and hinders the direct use of image processing and machine intelligence techniques on the recorded signal. Significant efforts have been made by researchers in the recent past in the development and implementation of pixelation removal techniques. However, researchers have often used their own set of images without making source data available which subdued their usage and adaptability universally. A database of pixelated images is the current requirement to meet the growing diagnostic needs in the healthcare arena. An innovative fiber pixelated image database is presented, which consists of pixelated images that are synthetically generated and experimentally acquired. Sample space encompasses test patterns of different scales, sizes, and shapes. It is envisaged that this proposed database will alleviate the current limitations associated with relevant research and development and would be of great help for researchers working on comb structure removal algorithms.

  11. CMOS active pixel sensor type imaging system on a chip

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R. (Inventor); Nixon, Robert (Inventor)

    2011-01-01

    A single chip camera which includes an .[.intergrated.]. .Iadd.integrated .Iaddend.image acquisition portion and control portion and which has double sampling/noise reduction capabilities thereon. Part of the .[.intergrated.]. .Iadd.integrated .Iaddend.structure reduces the noise that is picked up during imaging.

  12. Integrated imaging sensor systems with CMOS active pixel sensor technology

    NASA Technical Reports Server (NTRS)

    Yang, G.; Cunningham, T.; Ortiz, M.; Heynssens, J.; Sun, C.; Hancock, B.; Seshadri, S.; Wrigley, C.; McCarty, K.; Pain, B.

    2002-01-01

    This paper discusses common approaches to CMOS APS technology, as well as specific results on the five-wire programmable digital camera-on-a-chip developed at JPL. The paper also reports recent research in the design, operation, and performance of APS imagers for several imager applications.

  13. Pixelated neutron image plates

    NASA Astrophysics Data System (ADS)

    Schlapp, M.; Conrad, H.; von Seggern, H.

    2004-09-01

    Neutron image plates (NIPs) have found widespread application as neutron detectors for single-crystal and powder diffraction, small-angle scattering and tomography. After neutron exposure, the image plate can be read out by scanning with a laser. Commercially available NIPs consist of a powder mixture of BaFBr : Eu2+ and Gd2O3 dispersed in a polymer matrix and supported by a flexible polymer sheet. Since BaFBr : Eu2+ is an excellent x-ray storage phosphor, these NIPs are particularly sensitive to ggr-radiation, which is always present as a background radiation in neutron experiments. In this work we present results on NIPs consisting of KCl : Eu2+ and LiF that were fabricated into ceramic image plates in which the alkali halides act as a self-supporting matrix without the necessity for using a polymeric binder. An advantage of this type of NIP is the significantly reduced ggr-sensitivity. However, the much lower neutron absorption cross section of LiF compared with Gd2O3 demands a thicker image plate for obtaining comparable neutron absorption. The greater thickness of the NIP inevitably leads to a loss in spatial resolution of the image plate. However, this reduction in resolution can be restricted by a novel image plate concept in which a ceramic structure with square cells (referred to as a 'honeycomb') is embedded in the NIP, resulting in a pixelated image plate. In such a NIP the read-out light is confined to the particular illuminated pixel, decoupling the spatial resolution from the optical properties of the image plate material and morphology. In this work, a comparison of experimentally determined and simulated spatial resolutions of pixelated and unstructured image plates for a fixed read-out laser intensity is presented, as well as simulations of the properties of these NIPs at higher laser powers.

  14. Imaging properties of pixellated scintillators with deep pixels

    PubMed Central

    Barber, H. Bradford; Fastje, David; Lemieux, Daniel; Grim, Gary P.; Furenlid, Lars R.; Miller, Brian W.; Parkhurst, Philip; Nagarkar, Vivek V.

    2015-01-01

    We have investigated the light-transport properties of scintillator arrays with long, thin pixels (deep pixels) for use in high-energy gamma-ray imaging. We compared 10×10 pixel arrays of YSO:Ce, LYSO:Ce and BGO (1mm × 1mm × 20 mm pixels) made by Proteus, Inc. with similar 10×10 arrays of LSO:Ce and BGO (1mm × 1mm × 15mm pixels) loaned to us by Saint-Gobain. The imaging and spectroscopic behaviors of these scintillator arrays are strongly affected by the choice of a reflector used as an inter-pixel spacer (3M ESR in the case of the Proteus arrays and white, diffuse-reflector for the Saint-Gobain arrays). We have constructed a 3700-pixel LYSO:Ce Prototype NIF Gamma-Ray Imager for use in diagnosing target compression in inertial confinement fusion. This system was tested at the OMEGA Laser and exhibited significant optical, inter-pixel cross-talk that was traced to the use of a single-layer of ESR film as an inter-pixel spacer. We show how the optical cross-talk can be mapped, and discuss correction procedures. We demonstrate a 10×10 YSO:Ce array as part of an iQID (formerly BazookaSPECT) imager and discuss issues related to the internal activity of 176Lu in LSO:Ce and LYSO:Ce detectors. PMID:26236070

  15. Imaging properties of pixellated scintillators with deep pixels

    NASA Astrophysics Data System (ADS)

    Barber, H. Bradford; Fastje, David; Lemieux, Daniel; Grim, Gary P.; Furenlid, Lars R.; Miller, Brian W.; Parkhurst, Philip; Nagarkar, Vivek V.

    2014-09-01

    We have investigated the light-transport properties of scintillator arrays with long, thin pixels (deep pixels) for use in high-energy gamma-ray imaging. We compared 10x10 pixel arrays of YSO:Ce, LYSO:Ce and BGO (1mm x 1mm x 20 mm pixels) made by Proteus, Inc. with similar 10x10 arrays of LSO:Ce and BGO (1mm x 1mm x 15mm pixels) loaned to us by Saint-Gobain. The imaging and spectroscopic behaviors of these scintillator arrays are strongly affected by the choice of a reflector used as an inter-pixel spacer (3M ESR in the case of the Proteus arrays and white, diffuse-reflector for the Saint-Gobain arrays). We have constructed a 3700-pixel LYSO:Ce Prototype NIF Gamma-Ray Imager for use in diagnosing target compression in inertial confinement fusion. This system was tested at the OMEGA Laser and exhibited significant optical, inter-pixel cross-talk that was traced to the use of a single-layer of ESR film as an inter-pixel spacer. We show how the optical cross-talk can be mapped, and discuss correction procedures. We demonstrate a 10x10 YSO:Ce array as part of an iQID (formerly BazookaSPECT) imager and discuss issues related to the internal activity of 176Lu in LSO:Ce and LYSO:Ce detectors.

  16. Imaging properties of pixellated scintillators with deep pixels.

    PubMed

    Barber, H Bradford; Fastje, David; Lemieux, Daniel; Grim, Gary P; Furenlid, Lars R; Miller, Brian W; Parkhurst, Philip; Nagarkar, Vivek V

    2014-08-17

    We have investigated the light-transport properties of scintillator arrays with long, thin pixels (deep pixels) for use in high-energy gamma-ray imaging. We compared 10×10 pixel arrays of YSO:Ce, LYSO:Ce and BGO (1mm × 1mm × 20 mm pixels) made by Proteus, Inc. with similar 10×10 arrays of LSO:Ce and BGO (1mm × 1mm × 15mm pixels) loaned to us by Saint-Gobain. The imaging and spectroscopic behaviors of these scintillator arrays are strongly affected by the choice of a reflector used as an inter-pixel spacer (3M ESR in the case of the Proteus arrays and white, diffuse-reflector for the Saint-Gobain arrays). We have constructed a 3700-pixel LYSO:Ce Prototype NIF Gamma-Ray Imager for use in diagnosing target compression in inertial confinement fusion. This system was tested at the OMEGA Laser and exhibited significant optical, inter-pixel cross-talk that was traced to the use of a single-layer of ESR film as an inter-pixel spacer. We show how the optical cross-talk can be mapped, and discuss correction procedures. We demonstrate a 10×10 YSO:Ce array as part of an iQID (formerly BazookaSPECT) imager and discuss issues related to the internal activity of (176)Lu in LSO:Ce and LYSO:Ce detectors.

  17. Active pixel image sensor with a winner-take-all mode of operation

    NASA Technical Reports Server (NTRS)

    Yadid-Pecht, Orly (Inventor); Fossum, Eric R. (Inventor); Mead, Carver (Inventor)

    2003-01-01

    An integrated CMOS semiconductor imaging device having two modes of operation that can be performed simultaneously to produce an output image and provide information of a brightest or darkest pixel in the image.

  18. Development of CMOS Active Pixel Image Sensors for Low Cost Commercial Applications

    NASA Technical Reports Server (NTRS)

    Gee, R.; Kemeny, S.; Kim, Q.; Mendis, S.; Nakamura, J.; Nixon, R.; Ortiz, M.; Pain, B.; Staller, C.; Zhou, Z; Fossum, E.

    1994-01-01

    JPL, under sponsorship from the NASA Office of Advanced Concepts and Technology, has been developing a second-generation solid-state image sensor technology. Charge-coupled devices (CCD) are a well-established first generation image sensor technology. For both commercial and NASA applications, CCDs have numerous shortcomings. In response, the active pixel sensor (APS) technology has been under research. The major advantages of APS technology are the ability to integrate on-chip timing, control, signal-processing and analog-to-digital converter functions, reduced sensitivity to radiation effects, low power operation, and random access readout.

  19. Characteristics of Monolithically Integrated InGaAs Active Pixel Imager Array

    NASA Technical Reports Server (NTRS)

    Kim, Q.; Cunningham, T. J.; Pain, B.; Lange, M. J.; Olsen, G. H.

    2000-01-01

    Switching and amplifying characteristics of a newly developed monolithic InGaAs Active Pixel Imager Array are presented. The sensor array is fabricated from InGaAs material epitaxially deposited on an InP substrate. It consists of an InGaAs photodiode connected to InP depletion-mode junction field effect transistors (JFETs) for low leakage, low power, and fast control of circuit signal amplifying, buffering, selection, and reset. This monolithically integrated active pixel sensor configuration eliminates the need for hybridization with silicon multiplexer. In addition, the configuration allows the sensor to be front illuminated, making it sensitive to visible as well as near infrared signal radiation. Adapting the existing 1.55 micrometer fiber optical communication technology, this integration will be an ideal system of optoelectronic integration for dual band (Visible/IR) applications near room temperature, for use in atmospheric gas sensing in space, and for target identification on earth. In this paper, two different types of small 4 x 1 test arrays will be described. The effectiveness of switching and amplifying circuits will be discussed in terms of circuit effectiveness (leakage, operating frequency, and temperature) in preparation for the second phase demonstration of integrated, two-dimensional monolithic InGaAs active pixel sensor arrays for applications in transportable shipboard surveillance, night vision, and emission spectroscopy.

  20. Performance of a novel wafer scale CMOS active pixel sensor for bio-medical imaging

    NASA Astrophysics Data System (ADS)

    Esposito, M.; Anaxagoras, T.; Konstantinidis, A. C.; Zheng, Y.; Speller, R. D.; Evans, P. M.; Allinson, N. M.; Wells, K.

    2014-07-01

    Recently CMOS active pixels sensors (APSs) have become a valuable alternative to amorphous silicon and selenium flat panel imagers (FPIs) in bio-medical imaging applications. CMOS APSs can now be scaled up to the standard 20 cm diameter wafer size by means of a reticle stitching block process. However, despite wafer scale CMOS APS being monolithic, sources of non-uniformity of response and regional variations can persist representing a significant challenge for wafer scale sensor response. Non-uniformity of stitched sensors can arise from a number of factors related to the manufacturing process, including variation of amplification, variation between readout components, wafer defects and process variations across the wafer due to manufacturing processes. This paper reports on an investigation into the spatial non-uniformity and regional variations of a wafer scale stitched CMOS APS. For the first time a per-pixel analysis of the electro-optical performance of a wafer CMOS APS is presented, to address inhomogeneity issues arising from the stitching techniques used to manufacture wafer scale sensors. A complete model of the signal generation in the pixel array has been provided and proved capable of accounting for noise and gain variations across the pixel array. This novel analysis leads to readout noise and conversion gain being evaluated at pixel level, stitching block level and in regions of interest, resulting in a coefficient of variation ⩽1.9%. The uniformity of the image quality performance has been further investigated in a typical x-ray application, i.e. mammography, showing a uniformity in terms of CNR among the highest when compared with mammography detectors commonly used in clinical practice. Finally, in order to compare the detection capability of this novel APS with the technology currently used (i.e. FPIs), theoretical evaluation of the detection quantum efficiency (DQE) at zero-frequency has been performed, resulting in a higher DQE for this

  1. Performance of a novel wafer scale CMOS active pixel sensor for bio-medical imaging.

    PubMed

    Esposito, M; Anaxagoras, T; Konstantinidis, A C; Zheng, Y; Speller, R D; Evans, P M; Allinson, N M; Wells, K

    2014-07-07

    Recently CMOS active pixels sensors (APSs) have become a valuable alternative to amorphous silicon and selenium flat panel imagers (FPIs) in bio-medical imaging applications. CMOS APSs can now be scaled up to the standard 20 cm diameter wafer size by means of a reticle stitching block process. However, despite wafer scale CMOS APS being monolithic, sources of non-uniformity of response and regional variations can persist representing a significant challenge for wafer scale sensor response. Non-uniformity of stitched sensors can arise from a number of factors related to the manufacturing process, including variation of amplification, variation between readout components, wafer defects and process variations across the wafer due to manufacturing processes. This paper reports on an investigation into the spatial non-uniformity and regional variations of a wafer scale stitched CMOS APS. For the first time a per-pixel analysis of the electro-optical performance of a wafer CMOS APS is presented, to address inhomogeneity issues arising from the stitching techniques used to manufacture wafer scale sensors. A complete model of the signal generation in the pixel array has been provided and proved capable of accounting for noise and gain variations across the pixel array. This novel analysis leads to readout noise and conversion gain being evaluated at pixel level, stitching block level and in regions of interest, resulting in a coefficient of variation ⩽1.9%. The uniformity of the image quality performance has been further investigated in a typical x-ray application, i.e. mammography, showing a uniformity in terms of CNR among the highest when compared with mammography detectors commonly used in clinical practice. Finally, in order to compare the detection capability of this novel APS with the technology currently used (i.e. FPIs), theoretical evaluation of the detection quantum efficiency (DQE) at zero-frequency has been performed, resulting in a higher DQE for this

  2. Development of CMOS Active Pixel Image Sensors for Low Cost Commercial Applications

    NASA Technical Reports Server (NTRS)

    Fossum, E.; Gee, R.; Kemeny, S.; Kim, Q.; Mendis, S.; Nakamura, J.; Nixon, R.; Ortiz, M.; Pain, B.; Zhou, Z.; Ackland, B.; Dickinson, A.; Eid, E.; Inglis, D.

    1994-01-01

    This paper describes ongoing research and development of CMOS active pixel image sensors for low cost commercial applications. A number of sensor designs have been fabricated and tested in both p-well and n-well technologies. Major elements in the development of the sensor include on-chip analog signal processing circuits for the reduction of fixed pattern noise, on-chip timing and control circuits and on-chip analog-to-digital conversion (ADC). Recent results and continuing efforts in these areas will be presented.

  3. Single-pixel hyperspectral imaging

    NASA Astrophysics Data System (ADS)

    Suo, Jinli; Wang, Yuwang; Bian, Liheng; Dai, Qionghai

    2016-10-01

    Conventional multispectral imaging methods detect photons of a 3D hyperspectral data cube separately either in the spatial or spectral dimension using array detectors, and are thus photon inefficient and spectrum range limited. Besides, they are usually bulky and highly expensive. To address these issues, this paper presents single-pixel multispectral imaging techniques, which are of high sensitivity, wide spectrum range, low cost and light weight. Two mechanisms are proposed, and experimental validation are also reported.

  4. Imaging of moving fiducial markers during radiotherapy using a fast, efficient active pixel sensor based EPID

    SciTech Connect

    Osmond, John P. F.; Zin, Hafiz M.; Harris, Emma J.; Lupica, Giovanni; Allinson, Nigel M.; Evans, Philip M.

    2011-11-15

    Purpose: The purpose of this work was to investigate the use of an experimental complementary metal-oxide-semiconductor (CMOS) active pixel sensor (APS) for tracking of moving fiducial markers during radiotherapy. Methods: The APS has an active area of 5.4 x 5.4 cm and maximum full frame read-out rate of 20 frame s{sup -1}, with the option to read out a region-of-interest (ROI) at an increased rate. It was coupled to a 4 mm thick ZnWO4 scintillator which provided a quantum efficiency (QE) of 8% for a 6 MV x-ray treatment beam. The APS was compared with a standard iViewGT flat panel amorphous Silicon (a-Si) electronic portal imaging device (EPID), with a QE of 0.34% and a frame-rate of 2.5 frame s{sup -1}. To investigate the ability of the two systems to image markers, four gold cylinders of length 8 mm and diameter 0.8, 1.2, 1.6, and 2 mm were placed on a motion-platform. Images of the stationary markers were acquired using the APS at a frame-rate of 20 frame s{sup -1}, and a dose-rate of 143 MU min{sup -1} to avoid saturation. EPID images were acquired at the maximum frame-rate of 2.5 frame s{sup -1}, and a reduced dose-rate of 19 MU min{sup -1} to provide a similar dose per frame to the APS. Signal-to-noise ratio (SNR) of the background signal and contrast-to-noise ratio (CNR) of the marker signal relative to the background were evaluated for both imagers at doses of 0.125 to 2 MU. Results: Image quality and marker visibility was found to be greater in the APS with SNR {approx}5 times greater than in the EPID and CNR up to an order of magnitude greater for all four markers. To investigate the ability to image and track moving markers the motion-platform was moved to simulate a breathing cycle with period 6 s, amplitude 20 mm and maximum speed 13.2 mm s{sup -1}. At the minimum integration time of 50 ms a tracking algorithm applied to the APS data found all four markers with a success rate of {>=}92% and positional error {<=}90 {mu}m. At an integration time of 400

  5. SAR Image Complex Pixel Representations

    SciTech Connect

    Doerry, Armin W.

    2015-03-01

    Complex pixel values for Synthetic Aperture Radar (SAR) images of uniform distributed clutter can be represented as either real/imaginary (also known as I/Q) values, or as Magnitude/Phase values. Generally, these component values are integers with limited number of bits. For clutter energy well below full-scale, Magnitude/Phase offers lower quantization noise than I/Q representation. Further improvement can be had with companding of the Magnitude value.

  6. Signal and noise transfer properties of CMOS based active pixel flat panel imager coupled to structured CsI:Tl.

    PubMed

    Arvanitis, C D; Bohndiek, S E; Blakesley, J; Olivo, A; Speller, R D

    2009-01-01

    Complementary metal-oxide-semiconductors (CMOS) active pixel sensors can be optically coupled to CsI:Tl phosphors forming a indirect active pixel flat panel imager (APFPI) for high performance medical imaging. The aim of this work is to determine the x-ray imaging capabilities of CMOS-based APFPI and study the signal and noise transfer properties of CsI:Tl phosphors. Three different CsI:Tl phosphors from two different vendors have been used to produce three system configurations. The performance of each system configuration has been studied in terms of the modulation transfer function (MTF), noise power spectra, and detective quantum efficiency (DQE) in the mammographic energy range. A simple method to determine quantum limited systems in this energy range is also presented. In addition, with aid of monochromatic synchrotron radiation, the effect of iodine characteristic x-rays of the CsI:Tl on the MTF has been determined. A Monte Carlo simulation of the signal transfer properties of the imager is also presented in order to study the stages that degrade the spatial resolution of our current system. The effect of using substrate patterning during the growth of CsI:Tl columnar structure was also studied, along with the effect of CsI:Tl fixed pattern noise due to local variations in the scintillation light. CsI:Tl fixed pattern noise appears to limit the performance of our current system configurations. All the system configurations are quantum limited at 0.23 microC/kg with two of them having DQE (0) equal to 0.57. Active pixel flat panel imagers are shown to be digital x-ray imagers with almost constant DQE throughout a significant part of their dynamic range and in particular at very low exposures.

  7. Synchrotron based planar imaging and digital tomosynthesis of breast and biopsy phantoms using a CMOS active pixel sensor.

    PubMed

    Szafraniec, Magdalena B; Konstantinidis, Anastasios C; Tromba, Giuliana; Dreossi, Diego; Vecchio, Sara; Rigon, Luigi; Sodini, Nicola; Naday, Steve; Gunn, Spencer; McArthur, Alan; Olivo, Alessandro

    2015-03-01

    The SYRMEP (SYnchrotron Radiation for MEdical Physics) beamline at Elettra is performing the first mammography study on human patients using free-space propagation phase contrast imaging. The stricter spatial resolution requirements of this method currently force the use of conventional films or specialized computed radiography (CR) systems. This also prevents the implementation of three-dimensional (3D) approaches. This paper explores the use of an X-ray detector based on complementary metal-oxide-semiconductor (CMOS) active pixel sensor (APS) technology as a possible alternative, for acquisitions both in planar and tomosynthesis geometry. Results indicate higher quality of the images acquired with the synchrotron set-up in both geometries. This improvement can be partly ascribed to the use of parallel, collimated and monochromatic synchrotron radiation (resulting in scatter rejection, no penumbra-induced blurring and optimized X-ray energy), and partly to phase contrast effects. Even though the pixel size of the used detector is still too large - and thus suboptimal - for free-space propagation phase contrast imaging, a degree of phase-induced edge enhancement can clearly be observed in the images.

  8. CMOS Active Pixel Sensor Technology and Reliability Characterization Methodology

    NASA Technical Reports Server (NTRS)

    Chen, Yuan; Guertin, Steven M.; Pain, Bedabrata; Kayaii, Sammy

    2006-01-01

    This paper describes the technology, design features and reliability characterization methodology of a CMOS Active Pixel Sensor. Both overall chip reliability and pixel reliability are projected for the imagers.

  9. Pixels, Imagers and Related Fabrication Methods

    NASA Technical Reports Server (NTRS)

    Pain, Bedabrata (Inventor); Cunningham, Thomas J. (Inventor)

    2014-01-01

    Pixels, imagers and related fabrication methods are described. The described methods result in cross-talk reduction in imagers and related devices by generating depletion regions. The devices can also be used with electronic circuits for imaging applications.

  10. Pixels, Imagers and Related Fabrication Methods

    NASA Technical Reports Server (NTRS)

    Pain, Bedabrata (Inventor); Cunningham, Thomas J. (Inventor)

    2016-01-01

    Pixels, imagers and related fabrication methods are described. The described methods result in cross-talk reduction in imagers and related devices by generating depletion regions. The devices can also be used with electronic circuits for imaging applications.

  11. Large area CMOS active pixel sensor x-ray imager for digital breast tomosynthesis: Analysis, modeling, and characterization

    SciTech Connect

    Zhao, Chumin; Kanicki, Jerzy; Konstantinidis, Anastasios C.; Patel, Tushita

    2015-11-15

    Purpose: Large area x-ray imagers based on complementary metal-oxide-semiconductor (CMOS) active pixel sensor (APS) technology have been proposed for various medical imaging applications including digital breast tomosynthesis (DBT). The low electronic noise (50–300 e{sup −}) of CMOS APS x-ray imagers provides a possible route to shrink the pixel pitch to smaller than 75 μm for microcalcification detection and possible reduction of the DBT mean glandular dose (MGD). Methods: In this study, imaging performance of a large area (29 × 23 cm{sup 2}) CMOS APS x-ray imager [Dexela 2923 MAM (PerkinElmer, London)] with a pixel pitch of 75 μm was characterized and modeled. The authors developed a cascaded system model for CMOS APS x-ray imagers using both a broadband x-ray radiation and monochromatic synchrotron radiation. The experimental data including modulation transfer function, noise power spectrum, and detective quantum efficiency (DQE) were theoretically described using the proposed cascaded system model with satisfactory consistency to experimental results. Both high full well and low full well (LFW) modes of the Dexela 2923 MAM CMOS APS x-ray imager were characterized and modeled. The cascaded system analysis results were further used to extract the contrast-to-noise ratio (CNR) for microcalcifications with sizes of 165–400 μm at various MGDs. The impact of electronic noise on CNR was also evaluated. Results: The LFW mode shows better DQE at low air kerma (K{sub a} < 10 μGy) and should be used for DBT. At current DBT applications, air kerma (K{sub a} ∼ 10 μGy, broadband radiation of 28 kVp), DQE of more than 0.7 and ∼0.3 was achieved using the LFW mode at spatial frequency of 0.5 line pairs per millimeter (lp/mm) and Nyquist frequency ∼6.7 lp/mm, respectively. It is shown that microcalcifications of 165–400 μm in size can be resolved using a MGD range of 0.3–1 mGy, respectively. In comparison to a General Electric GEN2 prototype DBT system (at

  12. Equivalence of a Bit Pixel Image to a Quantum Pixel Image

    NASA Astrophysics Data System (ADS)

    Ortega, Laurel Carlos; Dong, Shi-Hai; Cruz-Irisson, M.

    2015-11-01

    We propose a new method to transform a pixel image to the corresponding quantum-pixel using a qubit per pixel to represent each pixels classical weight in a quantum image matrix weight. All qubits are linear superposition, changing the coefficients level by level to the entire longitude of the gray scale with respect to the base states of the qubit. Classically, these states are just bytes represented in a binary matrix, having code combinations of 1 or 0 at all pixel locations. This method introduces a qubit-pixel image representation of images captured by classical optoelectronic methods. Supported partially by the project 20150964-SIP-IPN, Mexico

  13. Analysis of pixel circuits in CMOS image sensors

    NASA Astrophysics Data System (ADS)

    Mei, Zou; Chen, Nan; Yao, Li-bin

    2015-04-01

    CMOS image sensors (CIS) have lower power consumption, lower cost and smaller size than CCD image sensors. However, generally CCDs have higher performance than CIS mainly due to lower noise. The pixel circuit used in CIS is the first part of the signal processing circuit and connected to photodiode directly, so its performance will greatly affect the CIS or even the whole imaging system. To achieve high performance, CMOS image sensors need advanced pixel circuits. There are many pixel circuits used in CIS, such as passive pixel sensor (PPS), 3T and 4T active pixel sensor (APS), capacitive transimpedance amplifier (CTIA), and passive pixel sensor (PPS). At first, the main performance parameters of each pixel structure including the noise, injection efficiency, sensitivity, power consumption, and stability of bias voltage are analyzed. Through the theoretical analysis of those pixel circuits, it is concluded that CTIA pixel circuit has good noise performance, high injection efficiency, stable photodiode bias, and high sensitivity with small integrator capacitor. Furthermore, the APS and CTIA pixel circuits are simulated in a standard 0.18-μm CMOS process and using a n-well/p-sub photodiode by SPICE and the simulation result confirms the theoretical analysis result. It shows the possibility that CMOS image sensors can be extended to a wide range of applications requiring high performance.

  14. Active Pixel Sensors: Are CCD's Dinosaurs?

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R.

    1993-01-01

    Charge-coupled devices (CCD's) are presently the technology of choice for most imaging applications. In the 23 years since their invention in 1970, they have evolved to a sophisticated level of performance. However, as with all technologies, we can be certain that they will be supplanted someday. In this paper, the Active Pixel Sensor (APS) technology is explored as a possible successor to the CCD. An active pixel is defined as a detector array technology that has at least one active transistor within the pixel unit cell. The APS eliminates the need for nearly perfect charge transfer -- the Achilles' heel of CCDs. This perfect charge transfer makes CCD's radiation 'soft,' difficult to use under low light conditions, difficult to manufacture in large array sizes, difficult to integrate with on-chip electronics, difficult to use at low temperatures, difficult to use at high frame rates, and difficult to manufacture in non-silicon materials that extend wavelength response.

  15. High-End CMOS Active Pixel Sensors For Space-Borne Imaging Instruments

    DTIC Science & Technology

    2005-07-13

    sur la technologie CCD, alors que les capteurs CMOS à pixel actifs (APS) ont des nombreux avantages pour des applications embarquées. Cette...Les capteurs optiques intégrés sont utilisés dans le domaine spatial dans un large éventail d’applications. Beaucoup d’entres elles reposent toujours...publication présente des capteurs CMOS hautes performances d’aujourd’hui et met en lumière leurs avantages par rapport à leur équivalent CCD. Ces capteurs

  16. Noise Characterization of Polycrystalline Silicon Thin Film Transistors for X-ray Imagers Based on Active Pixel Architectures.

    PubMed

    Antonuk, L E; Koniczek, M; McDonald, J; El-Mohri, Y; Zhao, Q; Behravan, M

    2008-01-01

    An examination of the noise of polycrystalline silicon thin film transistors, in the context of flat panel x-ray imager development, is reported. The study was conducted in the spirit of exploring how the 1/f, shot and thermal noise components of poly-Si TFTs, determined from current noise power spectral density measurements, as well as through calculation, can be used to assist in the development of imagers incorporating pixel amplification circuits based on such transistors.

  17. Holographic imaging with single pixel sensor

    NASA Astrophysics Data System (ADS)

    Leportier, Thibault; Lee, Young Tack; Hwang, Do Kyung; Park, Min-Chul

    2016-09-01

    Imaging techniques based on CCD sensors presenting very high number of pixels enable to record images with high resolution. However, the huge storage load and high bandwidth required to store and transmit digital holographic information are technical bottlenecks that should be overcome for the future of holographic display. Techniques to capture images with single pixel sensors have been greatly improved recently with the development of compressive sensing algorithm (CS). Since interference patterns may be considered sparse, the number of measurements required to recover the information with CS is lower than the number of pixels of the reconstructed image. In addition, this method does not need any scanning system. One other advantage of single pixel imaging is that the cost of recording system can be dramatically reduced since high-resolution cameras are expensive while compressive sensing exploits only one pixel. In this paper, we present an imaging system based on phase-shifting holography. First, simulations were performed to confirm that hologram could be reconstructed by compressive sensing even if the number of measurements was smaller than the number of pixels. Then, experimental set-up was realized. Several holograms with different phase shifts introduced by quarter and half wave plates in the reference beam were acquired. We demonstrated that our system enables the reconstruction of the object.

  18. Hybrid Pixel Detectors for gamma/X-ray imaging

    NASA Astrophysics Data System (ADS)

    Hatzistratis, D.; Theodoratos, G.; Zografos, V.; Kazas, I.; Loukas, D.; Lambropoulos, C. P.

    2015-09-01

    Hybrid pixel detectors are made by direct converting high-Z semi-insulating single crystalline material coupled to complementary-metal-oxide semiconductor (CMOS) readout electronics. They are attractive because direct conversion exterminates all the problems of spatial localization related to light diffusion, energy resolution, is far superior from the combination of scintillation crystals and photomultipliers and lithography can be used to pattern electrodes with very fine pitch. We are developing 2-D pixel CMOS ASICs, connect them to pixilated CdTe crystals with the flip chip and bump bonding method and characterize the hybrids. We have designed a series of circuits, whose latest member consists of a 50×25 pixel array with 400um pitch and an embedded controller. In every pixel a full spectroscopic channel with time tagging information has been implemented. The detectors are targeting Compton scatter imaging and they can be used for coded aperture imaging too. Hybridization using CMOS can overcome the limit put on pixel circuit complexity by the use of thin film transistors (TFT) in large flat panels. Hybrid active pixel sensors are used in dental imaging and other applications (e.g. industrial CT etc.). Thus X-ray imaging can benefit from the work done on dynamic range enhancement methods developed initially for visible and infrared CMOS pixel sensors. A 2-D CMOS ASIC with 100um pixel pitch to demonstrate the feasibility of such methods in the context of X-ray imaging has been designed.

  19. LISe pixel detector for neutron imaging

    NASA Astrophysics Data System (ADS)

    Herrera, Elan; Hamm, Daniel; Wiggins, Brenden; Milburn, Rob; Burger, Arnold; Bilheux, Hassina; Santodonato, Louis; Chvala, Ondrej; Stowe, Ashley; Lukosi, Eric

    2016-10-01

    Semiconducting lithium indium diselenide, 6LiInSe2 or LISe, has promising characteristics for neutron detection applications. The 95% isotopic enrichment of 6Li results in a highly efficient thermal neutron-sensitive material. In this study, we report on a proof-of-principle investigation of a semiconducting LISe pixel detector to demonstrate its potential as an efficient neutron imager. The LISe pixel detector had a 4×4 of pixels with a 550 μm pitch on a 5×5×0.56 mm3 LISe substrate. An experimentally verified spatial resolution of 300 μm was observed utilizing a super-sampling technique.

  20. Toward Multispectral Imaging with Colloidal Metasurface Pixels.

    PubMed

    Stewart, Jon W; Akselrod, Gleb M; Smith, David R; Mikkelsen, Maiken H

    2017-02-01

    Multispectral colloidal metasurfaces are fabricated that exhibit greater than 85% absorption and ≈100 nm linewidths by patterning film-coupled nanocubes in pixels using a fusion of bottom-up and top-down fabrication techniques over wafer-scale areas. With this technique, the authors realize a multispectral pixel array consisting of six resonances between 580 and 1125 nm and reconstruct an RGB image with 9261 color combinations.

  1. High-dynamic-range pixel architectures for diagnostic medical imaging

    NASA Astrophysics Data System (ADS)

    Karim, Karim S.; Yin, Sherman; Nathan, Arokia; Rowlands, John A.

    2004-05-01

    One approach to increase pixel signal-to-noise ratio (SNR) in low noise digital fluoroscopy is to employ in-situ pixel amplification via current-mediated active pixel sensors (C-APS). Experiments reveal a reduction in readout noise and indicate that an a-Si C-APS, coupled together with an established X-ray detection technology such as amorphous selenium (a-Se), can meet the stringent requirements (of < 1000 noise electrons) for digital X-ray fluoroscopy. A challenge with the C-APS circuit is the presence of a small-signal input linearity constraint. While using such a pixel amplifier for real-time fluoroscopy (where the exposure level is small) is feasible, the voltage change at the amplifier input is much higher in chest radiography or mammography due to the larger X-ray exposure levels. The larger input voltage causes the C-APS output to be non-linear thus reducing the pixel dynamic range. In addition, the resulting larger pixel output current causes the external column amplifier to saturate further reducing the pixel dynamic range. In this research, we investigate two alternate amplified pixel architectures that exhibit higher dynamic range. The test pixels are designed and simulated using an a-Si TFT model implemented in Verilog-A and results indicate a linear performance, high dynamic range, and a programmable circuit gain via choice of supply voltage and sampling time. These high dynamic range pixel architectures have the potential to enable a large area, active matrix flat panel imager (AMFPI) to switch instantly between low exposure, fluoroscopic imaging and higher exposure radiographic imaging modes. Lastly, the high dynamic range pixel circuits are suitable for integration with on-panel multiplexers for both gate and data lines, which can further reduce circuit complexity.

  2. Method and apparatus of high dynamic range image sensor with individual pixel reset

    NASA Technical Reports Server (NTRS)

    Yadid-Pecht, Orly (Inventor); Pain, Bedabrata (Inventor); Fossum, Eric R. (Inventor)

    2001-01-01

    A wide dynamic range image sensor provides individual pixel reset to vary the integration time of individual pixels. The integration time of each pixel is controlled by column and row reset control signals which activate a logical reset transistor only when both signals coincide for a given pixel.

  3. Amorphous In–Ga–Zn–O thin-film transistor active pixel sensor x-ray imager for digital breast tomosynthesis

    SciTech Connect

    Zhao, Chumin; Kanicki, Jerzy

    2014-09-15

    Purpose: The breast cancer detection rate for digital breast tomosynthesis (DBT) is limited by the x-ray image quality. The limiting Nyquist frequency for current DBT systems is around 5 lp/mm, while the fine image details contained in the high spatial frequency region (>5 lp/mm) are lost. Also today the tomosynthesis patient dose is high (0.67–3.52 mGy). To address current issues, in this paper, for the first time, a high-resolution low-dose organic photodetector/amorphous In–Ga–Zn–O thin-film transistor (a-IGZO TFT) active pixel sensor (APS) x-ray imager is proposed for next generation DBT systems. Methods: The indirect x-ray detector is based on a combination of a novel low-cost organic photodiode (OPD) and a cesium iodide-based (CsI:Tl) scintillator. The proposed APS x-ray imager overcomes the difficulty of weak signal detection, when small pixel size and low exposure conditions are used, by an on-pixel signal amplification with a significant charge gain. The electrical performance of a-IGZO TFT APS pixel circuit is investigated by SPICE simulation using modified Rensselaer Polytechnic Institute amorphous silicon (a-Si:H) TFT model. Finally, the noise, detective quantum efficiency (DQE), and resolvability of the complete system are modeled using the cascaded system formalism. Results: The result demonstrates that a large charge gain of 31–122 is achieved for the proposed high-mobility (5–20 cm{sup 2}/V s) amorphous metal-oxide TFT APS. The charge gain is sufficient to eliminate the TFT thermal noise, flicker noise as well as the external readout circuit noise. Moreover, the low TFT (<10{sup −13} A) and OPD (<10{sup −8} A/cm{sup 2}) leakage currents can further reduce the APS noise. Cascaded system analysis shows that the proposed APS imager with a 75 μm pixel pitch can effectively resolve the Nyquist frequency of 6.67 lp/mm, which can be further improved to ∼10 lp/mm if the pixel pitch is reduced to 50 μm. Moreover, the

  4. Pixel-Level Simulation of Imaging Data

    NASA Astrophysics Data System (ADS)

    Stoughton, C.; Kuropatkin, N. P.; Neilsen, E., Jr.; Harms, D. C.

    2007-10-01

    We are preparing a set of Java packages to facilitate the design and operation of imaging surveys. The packages use shapelets to describe shapes of astronomical sources, optical distortions, and shear from weak gravitational lensing. We introduce noise, bad pixels, cosmic rays, the pupil image, saturation, and other observational effects. A set of utility classes handles I/O, plotting, and interfaces to existing packages: nom.tam.fits for FITS I/O; uk.ac.starlink.table for tables; and cern.colt for algorithms. The packages have been used to generate images for the Dark Energy Survey data challenges, and will be used by SNAP to continue evaluating its design.

  5. Analysis and Enhancement of Low-Light-Level Performance of Photodiode-Type CMOS Active Pixel Images Operated with Sub-Threshold Reset

    NASA Technical Reports Server (NTRS)

    Pain, Bedabrata; Yang, Guang; Ortiz, Monico; Wrigley, Christopher; Hancock, Bruce; Cunningham, Thomas

    2000-01-01

    Noise in photodiode-type CMOS active pixel sensors (APS) is primarily due to the reset (kTC) noise at the sense node, since it is difficult to implement in-pixel correlated double sampling for a 2-D array. Signal integrated on the photodiode sense node (SENSE) is calculated by measuring difference between the voltage on the column bus (COL) - before and after the reset (RST) is pulsed. Lower than kTC noise can be achieved with photodiode-type pixels by employing "softreset" technique. Soft-reset refers to resetting with both drain and gate of the n-channel reset transistor kept at the same potential, causing the sense node to be reset using sub-threshold MOSFET current. However, lowering of noise is achieved only at the expense higher image lag and low-light-level non-linearity. In this paper, we present an analysis to explain the noise behavior, show evidence of degraded performance under low-light levels, and describe new pixels that eliminate non-linearity and lag without compromising noise.

  6. Small pixel uncooled imaging FPAs and applications

    NASA Astrophysics Data System (ADS)

    Blackwell, Richard; Franks, Glen; Lacroix, Daniel; Hyland, Sandra; Murphy, Robert

    2010-04-01

    BAE Systems continues to make dramatic progress in uncooled microbolometer sensors and applications. This paper will review the latest advancements in microbolometer technology at BAE Systems, including the development status of 17 micrometer pixel pitch detectors and imaging modules which are entering production and will be finding their way into BAE Systems products and applications. Benefits include increased die per wafer and potential benefits to SWAP for many applications. Applications include thermal weapons sights, thermal imaging modules for remote weapon stations, vehicle situational awareness sensors and mast/pole mounted sensors.

  7. High responsivity CMOS imager pixel implemented in SOI technology

    NASA Technical Reports Server (NTRS)

    Zheng, X.; Wrigley, C.; Yang, G.; Pain, B.

    2000-01-01

    Availability of mature sub-micron CMOS technology and the advent of the new low noise active pixel sensor (APS) concept have enabled the development of low power, miniature, single-chip, CMOS digital imagers in the decade of the 1990's.

  8. Active pixel sensor with intra-pixel charge transfer

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R. (Inventor); Mendis, Sunetra (Inventor); Kemeny, Sabrina E. (Inventor)

    1995-01-01

    An imaging device formed as a monolithic complementary metal oxide semiconductor integrated circuit in an industry standard complementary metal oxide semiconductor process, the integrated circuit including a focal plane array of pixel cells, each one of the cells including a photogate overlying the substrate for accumulating photo-generated charge in an underlying portion of the substrate, a readout circuit including at least an output field effect transistor formed in the substrate, and a charge coupled device section formed on the substrate adjacent the photogate having a sensing node connected to the output transistor and at least one charge coupled device stage for transferring charge from the underlying portion of the substrate to the sensing node.

  9. Active pixel sensor with intra-pixel charge transfer

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R. (Inventor); Mendis, Sunetra (Inventor); Kemeny, Sabrina E. (Inventor)

    2003-01-01

    An imaging device formed as a monolithic complementary metal oxide semiconductor integrated circuit in an industry standard complementary metal oxide semiconductor process, the integrated circuit including a focal plane array of pixel cells, each one of the cells including a photogate overlying the substrate for accumulating photo-generated charge in an underlying portion of the substrate, a readout circuit including at least an output field effect transistor formed in the substrate, and a charge coupled device section formed on the substrate adjacent the photogate having a sensing node connected to the output transistor and at least one charge coupled device stage for transferring charge from the underlying portion of the substrate to the sensing node.

  10. Active pixel sensor with intra-pixel charge transfer

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R. (Inventor); Mendis, Sunetra (Inventor); Kemeny, Sabrina E. (Inventor)

    2004-01-01

    An imaging device formed as a monolithic complementary metal oxide semiconductor integrated circuit in an industry standard complementary metal oxide semiconductor process, the integrated circuit including a focal plane array of pixel cells, each one of the cells including a photogate overlying the substrate for accumulating photo-generated charge in an underlying portion of the substrate, a readout circuit including at least an output field effect transistor formed in the substrate, and a charge coupled device section formed on the substrate adjacent the photogate having a sensing node connected to the output transistor and at least one charge coupled device stage for transferring charge from the underlying portion of the substrate to the sensing node.

  11. Spatial clustering of pixels of a multispectral image

    DOEpatents

    Conger, James Lynn

    2014-08-19

    A method and system for clustering the pixels of a multispectral image is provided. A clustering system computes a maximum spectral similarity score for each pixel that indicates the similarity between that pixel and the most similar neighboring. To determine the maximum similarity score for a pixel, the clustering system generates a similarity score between that pixel and each of its neighboring pixels and then selects the similarity score that represents the highest similarity as the maximum similarity score. The clustering system may apply a filtering criterion based on the maximum similarity score so that pixels with similarity scores below a minimum threshold are not clustered. The clustering system changes the current pixel values of the pixels in a cluster based on an averaging of the original pixel values of the pixels in the cluster.

  12. Edge pixel response studies of edgeless silicon sensor technology for pixellated imaging detectors

    NASA Astrophysics Data System (ADS)

    Maneuski, D.; Bates, R.; Blue, A.; Buttar, C.; Doonan, K.; Eklund, L.; Gimenez, E. N.; Hynds, D.; Kachkanov, S.; Kalliopuska, J.; McMullen, T.; O'Shea, V.; Tartoni, N.; Plackett, R.; Vahanen, S.; Wraight, K.

    2015-03-01

    Silicon sensor technologies with reduced dead area at the sensor's perimeter are under development at a number of institutes. Several fabrication methods for sensors which are sensitive close to the physical edge of the device are under investigation utilising techniques such as active-edges, passivated edges and current-terminating rings. Such technologies offer the goal of a seamlessly tiled detection surface with minimum dead space between the individual modules. In order to quantify the performance of different geometries and different bulk and implant types, characterisation of several sensors fabricated using active-edge technology were performed at the B16 beam line of the Diamond Light Source. The sensors were fabricated by VTT and bump-bonded to Timepix ROICs. They were 100 and 200 μ m thick sensors, with the last pixel-to-edge distance of either 50 or 100 μ m. The sensors were fabricated as either n-on-n or n-on-p type devices. Using 15 keV monochromatic X-rays with a beam spot of 2.5 μ m, the performance at the outer edge and corners pixels of the sensors was evaluated at three bias voltages. The results indicate a significant change in the charge collection properties between the edge and 5th (up to 275 μ m) from edge pixel for the 200 μ m thick n-on-n sensor. The edge pixel performance of the 100 μ m thick n-on-p sensors is affected only for the last two pixels (up to 110 μ m) subject to biasing conditions. Imaging characteristics of all sensor types investigated are stable over time and the non-uniformities can be minimised by flat-field corrections. The results from the synchrotron tests combined with lab measurements are presented along with an explanation of the observed effects.

  13. Steganography on quantum pixel images using Shannon entropy

    NASA Astrophysics Data System (ADS)

    Laurel, Carlos Ortega; Dong, Shi-Hai; Cruz-Irisson, M.

    2016-07-01

    This paper presents a steganographical algorithm based on least significant bit (LSB) from the most significant bit information (MSBI) and the equivalence of a bit pixel image to a quantum pixel image, which permits to make the information communicate secretly onto quantum pixel images for its secure transmission through insecure channels. This algorithm offers higher security since it exploits the Shannon entropy for an image.

  14. Fault tolerant photodiode and photogate active pixel sensors

    NASA Astrophysics Data System (ADS)

    Jung, Cory; Chapman, Glenn H.; La Haye, Michelle L.; Djaja, Sunjaya; Cheung, Desmond Y. H.; Lin, Henry; Loo, Edward; Audet, Yves R.

    2005-03-01

    As the pixel counts of digital imagers increase, the challenge of maintaining high yields and ensuring reliability over an imager"s lifetime increases. A fault tolerant active pixel sensor (APS) has been designed to meet this need by splitting an APS in half and operating both halves in parallel. The fault tolerant APS will perform normally in the no defect case and will produce approximately half the output for single defects. Thus, the entire signal can be recovered by multiplying the output by two. Since pixels containing multiple defects are rare, this design can correct for most defects allowing for higher production yields. Fault tolerant photodiode and photogate APS" were fabricated in 0.18-micron technology. Testing showed that the photodiode APS could correct for optically induced and electrically induced faults, within experimental error. The photogate APS was only tested for optically induced defects and also corrects for defects within experimental error. Further testing showed that the sensitivity of fault tolerant pixels was approximately 2-3 times more sensitive than the normal pixels. HSpice simulations of the fault tolerant APS circuit did not show increased sensitivity, however an equivalent normal APS circuit with twice width readout and row transistors was 1.90 times more sensitive than a normal pixel.

  15. Pixel response function experimental techniques and analysis of active pixel sensor star cameras

    NASA Astrophysics Data System (ADS)

    Fumo, Patrick; Waldron, Erik; Laine, Juha-Pekka; Evans, Gary

    2015-04-01

    The pixel response function (PRF) of a pixel within a focal plane is defined as the pixel intensity with respect to the position of a point source within the pixel. One of its main applications is in the field of astrometry, which is a branch of astronomy that deals with positioning data of a celestial body for tracking movement or adjusting the attitude of a spacecraft. Complementary metal oxide semiconductor (CMOS) image sensors generally offer better radiation tolerance to protons and heavy ions than CCDs making them ideal candidates for space applications aboard satellites, but like all image sensors they are limited by their spatial frequency response, better known as the modulation transfer function. Having a well-calibrated PRF allows us to eliminate some of the uncertainty in the spatial response of the system providing better resolution and a more accurate centroid estimation. This paper describes the experimental setup for determining the PRF of a CMOS image sensor and analyzes the effect on the oversampled point spread function (PSF) of an image intensifier, as well as the effects due to the wavelength of light used as a point source. It was found that using electron bombarded active pixel sensor (EBAPS) intensification technology had a significant impact on the PRF of the camera being tested as a result of an increase in the amount of carrier diffusion between collection sites generated by the intensification process. Taking the full width at half maximum (FWHM) of the resulting data, it was found that the intensified version of a CMOS camera exhibited a PSF roughly 16.42% larger than its nonintensified counterpart.

  16. Analysis of Multipath Pixels in SAR Images

    NASA Astrophysics Data System (ADS)

    Zhao, J. W.; Wu, J. C.; Ding, X. L.; Zhang, L.; Hu, F. M.

    2016-06-01

    As the received radar signal is the sum of signal contributions overlaid in one single pixel regardless of the travel path, the multipath effect should be seriously tackled as the multiple bounce returns are added to direct scatter echoes which leads to ghost scatters. Most of the existing solution towards the multipath is to recover the signal propagation path. To facilitate the signal propagation simulation process, plenty of aspects such as sensor parameters, the geometry of the objects (shape, location, orientation, mutual position between adjacent buildings) and the physical parameters of the surface (roughness, correlation length, permittivity)which determine the strength of radar signal backscattered to the SAR sensor should be given in previous. However, it's not practical to obtain the highly detailed object model in unfamiliar area by field survey as it's a laborious work and time-consuming. In this paper, SAR imaging simulation based on RaySAR is conducted at first aiming at basic understanding of multipath effects and for further comparison. Besides of the pre-imaging simulation, the product of the after-imaging, which refers to radar images is also taken into consideration. Both Cosmo-SkyMed ascending and descending SAR images of Lupu Bridge in Shanghai are used for the experiment. As a result, the reflectivity map and signal distribution map of different bounce level are simulated and validated by 3D real model. The statistic indexes such as the phase stability, mean amplitude, amplitude dispersion, coherence and mean-sigma ratio in case of layover are analyzed with combination of the RaySAR output.

  17. Active pixel sensor array with multiresolution readout

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R. (Inventor); Kemeny, Sabrina E. (Inventor); Pain, Bedabrata (Inventor)

    1999-01-01

    An imaging device formed as a monolithic complementary metal oxide semiconductor integrated circuit in an industry standard complementary metal oxide semiconductor process, the integrated circuit including a focal plane array of pixel cells, each one of the cells including a photogate overlying the substrate for accumulating photo-generated charge in an underlying portion of the substrate and a charge coupled device section formed on the substrate adjacent the photogate having a sensing node and at least one charge coupled device stage for transferring charge from the underlying portion of the substrate to the sensing node. There is also a readout circuit, part of which can be disposed at the bottom of each column of cells and be common to all the cells in the column. The imaging device can also include an electronic shutter formed on the substrate adjacent the photogate, and/or a storage section to allow for simultaneous integration. In addition, the imaging device can include a multiresolution imaging circuit to provide images of varying resolution. The multiresolution circuit could also be employed in an array where the photosensitive portion of each pixel cell is a photodiode. This latter embodiment could further be modified to facilitate low light imaging.

  18. An integrating CMOS APS for X-ray imaging with an in-pixel preamplifier

    NASA Astrophysics Data System (ADS)

    Abdalla, M. A.; Fröjdh, C.; Petersson, C. S.

    2001-06-01

    We present in this paper an integrating CMOS Active Pixel Sensor (APS) circuit coated with scintillator type sensors for intra-oral dental X-ray imaging systems. The photosensing element in the pixel is formed by the p-diffusion on the n-well diode. The advantage of this photosensor is its very low direct absorption of X-rays compared to the other available photosensing elements in the CMOS pixel. The pixel features an integrating capacitor in the feedback loop of a preamplifier of a finite gain in order to increase the optical sensitivity. To verify the effectiveness of this in-pixel preamplification, a prototype 32×80 element CMOS active pixel array was implemented in a 0.8 μm CMOS double poly, n-well process with a pixel pitch of 50 μm. Measured results confirmed the improved optical sensitivity performance of the APS. Various measurements on device performance are presented.

  19. Image pixel device using integrated organic electronic components

    NASA Astrophysics Data System (ADS)

    Swathi, K.; Narayan, K. S.

    2016-11-01

    We report a solution processed, monolithically integrated device similar to an imaging pixel element used in complementary metal-oxide semiconductor (CMOS) based cameras. This integrated pixel essentially consists of a pair of organic photodiode (OPD) and organic field effect transistor (OFET). The signal generated by the light responsive OPD drives the OFET to different output states to quantify the light intensity. The prerequisite of a low operating voltage OFET (<2 V) was achieved using a bottom-gate, top-contact OFET consisting of a high mobility polymer semiconductor and a self-assembled hybrid dielectric layer. A bulk heterojunction blend was used as the photo-active layer in the OPD along with suitable buffer layers for charge extraction. The material parameters were optimized to realize a suitable structure which clearly demonstrated the interplay of the OPD and OFET operations, thereby forming a roadmap for all-organic CMOS arrays.

  20. CMOS VLSI Active-Pixel Sensor for Tracking

    NASA Technical Reports Server (NTRS)

    Pain, Bedabrata; Sun, Chao; Yang, Guang; Heynssens, Julie

    2004-01-01

    An architecture for a proposed active-pixel sensor (APS) and a design to implement the architecture in a complementary metal oxide semiconductor (CMOS) very-large-scale integrated (VLSI) circuit provide for some advanced features that are expected to be especially desirable for tracking pointlike features of stars. The architecture would also make this APS suitable for robotic- vision and general pointing and tracking applications. CMOS imagers in general are well suited for pointing and tracking because they can be configured for random access to selected pixels and to provide readout from windows of interest within their fields of view. However, until now, the architectures of CMOS imagers have not supported multiwindow operation or low-noise data collection. Moreover, smearing and motion artifacts in collected images have made prior CMOS imagers unsuitable for tracking applications. The proposed CMOS imager (see figure) would include an array of 1,024 by 1,024 pixels containing high-performance photodiode-based APS circuitry. The pixel pitch would be 9 m. The operations of the pixel circuits would be sequenced and otherwise controlled by an on-chip timing and control block, which would enable the collection of image data, during a single frame period, from either the full frame (that is, all 1,024 1,024 pixels) or from within as many as 8 different arbitrarily placed windows as large as 8 by 8 pixels each. A typical prior CMOS APS operates in a row-at-a-time ( grolling-shutter h) readout mode, which gives rise to exposure skew. In contrast, the proposed APS would operate in a sample-first/readlater mode, suppressing rolling-shutter effects. In this mode, the analog readout signals from the pixels corresponding to the windows of the interest (which windows, in the star-tracking application, would presumably contain guide stars) would be sampled rapidly by routing them through a programmable diagonal switch array to an on-chip parallel analog memory array. The

  1. Sub-pixel spatial resolution wavefront phase imaging

    NASA Technical Reports Server (NTRS)

    Stahl, H. Philip (Inventor); Mooney, James T. (Inventor)

    2012-01-01

    A phase imaging method for an optical wavefront acquires a plurality of phase images of the optical wavefront using a phase imager. Each phase image is unique and is shifted with respect to another of the phase images by a known/controlled amount that is less than the size of the phase imager's pixels. The phase images are then combined to generate a single high-spatial resolution phase image of the optical wavefront.

  2. Super pixel density based clustering automatic image classification method

    NASA Astrophysics Data System (ADS)

    Xu, Mingxing; Zhang, Chuan; Zhang, Tianxu

    2015-12-01

    The image classification is an important means of image segmentation and data mining, how to achieve rapid automated image classification has been the focus of research. In this paper, based on the super pixel density of cluster centers algorithm for automatic image classification and identify outlier. The use of the image pixel location coordinates and gray value computing density and distance, to achieve automatic image classification and outlier extraction. Due to the increased pixel dramatically increase the computational complexity, consider the method of ultra-pixel image preprocessing, divided into a small number of super-pixel sub-blocks after the density and distance calculations, while the design of a normalized density and distance discrimination law, to achieve automatic classification and clustering center selection, whereby the image automatically classify and identify outlier. After a lot of experiments, our method does not require human intervention, can automatically categorize images computing speed than the density clustering algorithm, the image can be effectively automated classification and outlier extraction.

  3. The Dexela 2923 CMOS X-ray detector: A flat panel detector based on CMOS active pixel sensors for medical imaging applications

    NASA Astrophysics Data System (ADS)

    Konstantinidis, Anastasios C.; Szafraniec, Magdalena B.; Speller, Robert D.; Olivo, Alessandro

    2012-10-01

    Complementary metal-oxide-semiconductors (CMOS) active pixel sensors (APS) have been introduced recently in many scientific applications. This work reports on the performance (in terms of signal and noise transfer) of an X-ray detector that uses a novel CMOS APS which was developed for medical X-ray imaging applications. For a full evaluation of the detector's performance, electro-optical and X-ray characterizations were carried out. The former included measuring read noise, full well capacity and dynamic range. The latter, which included measuring X-ray sensitivity, presampling modulation transfer function (pMTF), noise power spectrum (NPS) and the resulting detective quantum efficiency (DQE), was assessed under three beam qualities (28 kV, 50 kV (RQA3) and 70 kV (RQA5) using W/Al) all in accordance with the IEC standard. The detector features an in-pixel option for switching the full well capacity between two distinct modes, high full well (HFW) and low full well (LFW). Two structured CsI:Tl scintillators of different thickness (a “thin” one for high resolution and a thicker one for high light efficiency) were optically coupled to the sensor array to optimize the performance of the system for different medical applications. The electro-optical performance evaluation of the sensor results in relatively high read noise (∼360 e-), high full well capacity (∼1.5×106 e-) and wide dynamic range (∼73 dB) under HFW mode operation. When the LFW mode is used, the read noise is lower (∼165) at the expense of a reduced full well capacity (∼0.5×106 e-) and dynamic range (∼69 dB). The maximum DQE values at low frequencies (i.e. 0.5 lp/mm) are high for both HFW (0.69 for 28 kV, 0.71 for 50 kV and 0.75 for 70 kV) and LFW (0.69 for 28 kV and 0.7 for 50 kV) modes. The X-ray performance of the studied detector compares well to that of other mammography and general radiography systems, obtained under similar experimental conditions. This demonstrates the suitability

  4. Amplifier based broadband pixel for sub-millimeter wave imaging

    NASA Astrophysics Data System (ADS)

    Sarkozy, Stephen; Drewes, Jonathan; Leong, Kevin M. K. H.; Lai, Richard; Mei, X. B. (Gerry); Yoshida, Wayne; Lange, Michael D.; Lee, Jane; Deal, William R.

    2012-09-01

    Broadband sub-millimeter wave technology has received significant attention for potential applications in security, medical, and military imaging. Despite theoretical advantages of reduced size, weight, and power compared to current millimeter wave systems, sub-millimeter wave systems have been hampered by a fundamental lack of amplification with sufficient gain and noise figure properties. We report a broadband pixel operating from 300 to 340 GHz, biased off a single 2 V power supply. Over this frequency range, the amplifiers provide > 40 dB gain and <8 dB noise figure, representing the current state-of-art performance capabilities. This pixel is enabled by revolutionary enhancements to indium phosphide (InP) high electron mobility transistor technology, based on a sub-50 nm gate and indium arsenide composite channel with a projected maximum oscillation frequency fmax>1.0 THz. The first sub-millimeter wave-based images using active amplification are demonstrated as part of the Joint Improvised Explosive Device Defeat Organization Longe Range Personnel Imager Program. This development and demonstration may bring to life future sub-millimeter-wave and THz applications such as solutions to brownout problems, ultra-high bandwidth satellite communication cross-links, and future planetary exploration missions.

  5. A Chip and Pixel Qualification Methodology on Imaging Sensors

    NASA Technical Reports Server (NTRS)

    Chen, Yuan; Guertin, Steven M.; Petkov, Mihail; Nguyen, Duc N.; Novak, Frank

    2004-01-01

    This paper presents a qualification methodology on imaging sensors. In addition to overall chip reliability characterization based on sensor s overall figure of merit, such as Dark Rate, Linearity, Dark Current Non-Uniformity, Fixed Pattern Noise and Photon Response Non-Uniformity, a simulation technique is proposed and used to project pixel reliability. The projected pixel reliability is directly related to imaging quality and provides additional sensor reliability information and performance control.

  6. Active pixel sensor array with electronic shuttering

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R. (Inventor)

    2002-01-01

    An active pixel cell includes electronic shuttering capability. The cell can be shuttered to prevent additional charge accumulation. One mode transfers the current charge to a storage node that is blocked against accumulation of optical radiation. The charge is sampled from a floating node. Since the charge is stored, the node can be sampled at the beginning and the end of every cycle. Another aspect allows charge to spill out of the well whenever the charge amount gets higher than some amount, thereby providing anti blooming.

  7. Pixel-feature hybrid fusion for PET/CT images.

    PubMed

    Zhu, Yang-Ming; Nortmann, Charles A

    2011-02-01

    Color blending is a popular display method for functional and anatomic image fusion. The underlay image is typically displayed in grayscale, and the overlay image is displayed in pseudo colors. This pixel-level fusion provides too much information for reviewers to analyze quickly and effectively and clutters the display. To improve the fusion image reviewing speed and reduce the information clutter, a pixel-feature hybrid fusion method is proposed and tested for PET/CT images. Segments of the colormap are selectively masked to have a few discrete colors, and pixels displayed in the masked colors are made transparent. The colormap thus creates a false contouring effect on overlay images and allows the underlay to show through to give contours an anatomic context. The PET standardized uptake value (SUV) is used to control where colormap segments are masked. Examples show that SUV features can be extracted and blended with CT image instantaneously for viewing and diagnosis, and the non-feature part of the PET image is transparent. The proposed pixel-feature hybrid fusion highlights PET SUV features on CT images and reduces display clutters. It is easy to implement and can be used as complementarily to existing pixel-level fusion methods.

  8. Pixel classification based color image segmentation using quaternion exponent moments.

    PubMed

    Wang, Xiang-Yang; Wu, Zhi-Fang; Chen, Liang; Zheng, Hong-Liang; Yang, Hong-Ying

    2016-02-01

    Image segmentation remains an important, but hard-to-solve, problem since it appears to be application dependent with usually no a priori information available regarding the image structure. In recent years, many image segmentation algorithms have been developed, but they are often very complex and some undesired results occur frequently. In this paper, we propose a pixel classification based color image segmentation using quaternion exponent moments. Firstly, the pixel-level image feature is extracted based on quaternion exponent moments (QEMs), which can capture effectively the image pixel content by considering the correlation between different color channels. Then, the pixel-level image feature is used as input of twin support vector machines (TSVM) classifier, and the TSVM model is trained by selecting the training samples with Arimoto entropy thresholding. Finally, the color image is segmented with the trained TSVM model. The proposed scheme has the following advantages: (1) the effective QEMs is introduced to describe color image pixel content, which considers the correlation between different color channels, (2) the excellent TSVM classifier is utilized, which has lower computation time and higher classification accuracy. Experimental results show that our proposed method has very promising segmentation performance compared with the state-of-the-art segmentation approaches recently proposed in the literature.

  9. All-passive pixel super-resolution of time-stretch imaging

    PubMed Central

    Chan, Antony C. S.; Ng, Ho-Cheung; Bogaraju, Sharat C. V.; So, Hayden K. H.; Lam, Edmund Y.; Tsia, Kevin K.

    2017-01-01

    Based on image encoding in a serial-temporal format, optical time-stretch imaging entails a stringent requirement of state-of-the-art fast data acquisition unit in order to preserve high image resolution at an ultrahigh frame rate — hampering the widespread utilities of such technology. Here, we propose a pixel super-resolution (pixel-SR) technique tailored for time-stretch imaging that preserves pixel resolution at a relaxed sampling rate. It harnesses the subpixel shifts between image frames inherently introduced by asynchronous digital sampling of the continuous time-stretch imaging process. Precise pixel registration is thus accomplished without any active opto-mechanical subpixel-shift control or other additional hardware. Here, we present the experimental pixel-SR image reconstruction pipeline that restores high-resolution time-stretch images of microparticles and biological cells (phytoplankton) at a relaxed sampling rate (≈2–5 GSa/s)—more than four times lower than the originally required readout rate (20 GSa/s) — is thus effective for high-throughput label-free, morphology-based cellular classification down to single-cell precision. Upon integration with the high-throughput image processing technology, this pixel-SR time-stretch imaging technique represents a cost-effective and practical solution for large scale cell-based phenotypic screening in biomedical diagnosis and machine vision for quality control in manufacturing. PMID:28303936

  10. All-passive pixel super-resolution of time-stretch imaging

    NASA Astrophysics Data System (ADS)

    Chan, Antony C. S.; Ng, Ho-Cheung; Bogaraju, Sharat C. V.; So, Hayden K. H.; Lam, Edmund Y.; Tsia, Kevin K.

    2017-03-01

    Based on image encoding in a serial-temporal format, optical time-stretch imaging entails a stringent requirement of state-of-the-art fast data acquisition unit in order to preserve high image resolution at an ultrahigh frame rate — hampering the widespread utilities of such technology. Here, we propose a pixel super-resolution (pixel-SR) technique tailored for time-stretch imaging that preserves pixel resolution at a relaxed sampling rate. It harnesses the subpixel shifts between image frames inherently introduced by asynchronous digital sampling of the continuous time-stretch imaging process. Precise pixel registration is thus accomplished without any active opto-mechanical subpixel-shift control or other additional hardware. Here, we present the experimental pixel-SR image reconstruction pipeline that restores high-resolution time-stretch images of microparticles and biological cells (phytoplankton) at a relaxed sampling rate (≈2–5 GSa/s)—more than four times lower than the originally required readout rate (20 GSa/s) — is thus effective for high-throughput label-free, morphology-based cellular classification down to single-cell precision. Upon integration with the high-throughput image processing technology, this pixel-SR time-stretch imaging technique represents a cost-effective and practical solution for large scale cell-based phenotypic screening in biomedical diagnosis and machine vision for quality control in manufacturing.

  11. Metamaterial-based single pixel imaging system (Presentation Recording)

    NASA Astrophysics Data System (ADS)

    Padilla, Willie; Watts, Claire M.; Nadell, Christian; Montoya, John A.; Krishna, Sanjay

    2015-09-01

    Single pixel cameras are useful imaging devices where it is difficult or infeasible to fashion focal plan arrays. For example in the Far Infrared (FIR) it is difficult to perform imaging by conventional detector arrays, owing to the cost and size of such an array. The typical single pixel camera uses a spatial light modulator (SLM) - placed in the conjugate image plane - and is used to sample various portions of the image. The spatially modulated light emerging from the SLM is then sent to a single detector where the light is condensed with suitable optics for detection. Conventional SLMs are either based on liquid crystals or digital mirror devices. As such these devices are limited in modulation speeds of order 30 kHz. Further there is little control over the type of light that is modulated. We present metamaterial based spatial light modulators which provide the ability to digitally encode images - with various measurement matrix coefficients - thus permitting high speed and fidelity imaging capability. In particular we use the Hadamard matrix and related S-matrix to encode images for single pixel imaging. Metamaterials thus permit imaging in regimes of the electromagnetic spectrum where conventional SLMs are not available. Additionally, metamaterials offer several salient features that are not available with commercial SLMs. For example, metamaterials may be used to enable hyperspectral, polarimetric, and phase sensitive imaging. We present the theory and experimental results of single pixel imaging with digital metamaterials in the far infrared and highlight the future of this exciting field.

  12. Radiation tolerance of CMOS monolithic active pixel sensors with self-biased pixels

    NASA Astrophysics Data System (ADS)

    Deveaux, M.; Amar-Youcef, S.; Besson, A.; Claus, G.; Colledani, C.; Dorokhov, M.; Dritsa, C.; Dulinski, W.; Fröhlich, I.; Goffe, M.; Grandjean, D.; Heini, S.; Himmi, A.; Hu, C.; Jaaskelainen, K.; Müntz, C.; Shabetai, A.; Stroth, J.; Szelezniak, M.; Valin, I.; Winter, M.

    2010-12-01

    CMOS monolithic active pixel sensors (MAPS) are proposed as a technology for various vertex detectors in nuclear and particle physics. We discuss the mechanisms of ionizing radiation damage on MAPS hosting the dead time free, so-called self bias pixel. Moreover, we introduce radiation hardened sensor designs which allow operating detectors after exposing them to irradiation doses above 1 Mrad.

  13. A semiconductor radiation imaging pixel detector for space radiation dosimetry.

    PubMed

    Kroupa, Martin; Bahadori, Amir; Campbell-Ricketts, Thomas; Empl, Anton; Hoang, Son Minh; Idarraga-Munoz, John; Rios, Ryan; Semones, Edward; Stoffle, Nicholas; Tlustos, Lukas; Turecek, Daniel; Pinsky, Lawrence

    2015-07-01

    Progress in the development of high-performance semiconductor radiation imaging pixel detectors based on technologies developed for use in high-energy physics applications has enabled the development of a completely new generation of compact low-power active dosimeters and area monitors for use in space radiation environments. Such detectors can provide real-time information concerning radiation exposure, along with detailed analysis of the individual particles incident on the active medium. Recent results from the deployment of detectors based on the Timepix from the CERN-based Medipix2 Collaboration on the International Space Station (ISS) are reviewed, along with a glimpse of developments to come. Preliminary results from Orion MPCV Exploration Flight Test 1 are also presented.

  14. Pixel extraction based integral imaging with controllable viewing direction

    NASA Astrophysics Data System (ADS)

    Ji, Chao-Chao; Deng, Huan; Wang, Qiong-Hua

    2012-09-01

    We propose pixel extraction based integral imaging with a controllable viewing direction. The proposed integral imaging can provide viewers three-dimensional (3D) images in a very small viewing angle. The viewing angle and the viewing direction of the reconstructed 3D images are controlled by the pixels extracted from an elemental image array. Theoretical analysis and a 3D display experiment of the viewing direction controllable integral imaging are carried out. The experimental results verify the correctness of the theory. A 3D display based on the integral imaging can protect the viewer’s privacy and has huge potential for a television to show multiple 3D programs at the same time.

  15. Multiport solid-state imager characterization at variable pixel rates

    SciTech Connect

    Yates, G.J.; Albright, K.A.; Turko, B.T.

    1993-08-01

    The imaging performance of an 8-port Full Frame Transfer Charge Coupled Device (FFT CCD) as a function of several parameters including pixel clock rate is presented. The device, model CCD- 13, manufactured by English Electric Valve (EEV) is a 512 {times} 512 pixel array designed with four individual programmable bidirectional serial registers and eight output amplifiers permitting simultaneous readout of eight segments (128 horizontal {times} 256 vertical pixels) of the array. The imager was evaluated in Los Alamos National Laboratory`s High-Speed Solid-State Imager Test Station at true pixel rates as high as 50 MHz for effective imager pixel rates approaching 400 MHz from multiporting. Key response characteristics measured include absolute responsivity, Charge-Transfer-Efficiency (CTE), dynamic range, resolution, signal-to-noise ratio, and electronic and optical crosstalk among the eight video channels. Preliminary test results and data obtained from the CCD-13 will be presented and the versatility/capabilities of the test station will be reviewed.

  16. Acousto-optic imaging with a smart-pixels sensor

    NASA Astrophysics Data System (ADS)

    Barjean, K.; Contreras, K.; Laudereau, J.-B.; Tinet, E.; Ettori, D.; Ramaz, F.; Tualle, J.-M.

    2015-03-01

    Acousto-optic imaging (AOI) is an emerging technique in the field of biomedical optics which combines the optical contrast allowed by diffuse optical tomography with the resolution of ultrasound (US) imaging. In this work we report the implementation, for that purpose, of a CMOS smart-pixels sensor dedicated to the real-time analysis of speckle patterns. We implemented a highly sensitive lock-in detection in each pixel in order to extract the tagged photons after an appropriate in-pixel post-processing. With this system we can acquire images in scattering samples with a spatial resolution in the 2mm range, with an integration time compatible with the dynamic of living biological tissue.

  17. Using Trained Pixel Classifiers to Select Images of Interest

    NASA Technical Reports Server (NTRS)

    Mazzoni, D.; Wagstaff, K.; Castano, R.

    2004-01-01

    We present a machine-learning-based approach to ranking images based on learned priorities. Unlike previous methods for image evaluation, which typically assess the value of each image based on the presence of predetermined specific features, this method involves using two levels of machine-learning classifiers: one level is used to classify each pixel as belonging to one of a group of rather generic classes, and another level is used to rank the images based on these pixel classifications, given some example rankings from a scientist as a guide. Initial results indicate that the technique works well, producing new rankings that match the scientist's rankings significantly better than would be expected by chance. The method is demonstrated for a set of images collected by a Mars field-test rover.

  18. A CMOS In-Pixel CTIA High Sensitivity Fluorescence Imager

    PubMed Central

    Murari, Kartikeya; Etienne-Cummings, Ralph; Thakor, Nitish; Cauwenberghs, Gert

    2012-01-01

    Traditionally, charge coupled device (CCD) based image sensors have held sway over the field of biomedical imaging. Complementary metal oxide semiconductor (CMOS) based imagers so far lack sensitivity leading to poor low-light imaging. Certain applications including our work on animal-mountable systems for imaging in awake and unrestrained rodents require the high sensitivity and image quality of CCDs and the low power consumption, flexibility and compactness of CMOS imagers. We present a 132×124 high sensitivity imager array with a 20.1 μm pixel pitch fabricated in a standard 0.5 μ CMOS process. The chip incorporates n-well/p-sub photodiodes, capacitive transimpedance amplifier (CTIA) based in-pixel amplification, pixel scanners and delta differencing circuits. The 5-transistor all-nMOS pixel interfaces with peripheral pMOS transistors for column-parallel CTIA. At 70 fps, the array has a minimum detectable signal of 4 nW/cm2 at a wavelength of 450 nm while consuming 718 μA from a 3.3 V supply. Peak signal to noise ratio (SNR) was 44 dB at an incident intensity of 1 μW/cm2. Implementing 4×4 binning allowed the frame rate to be increased to 675 fps. Alternately, sensitivity could be increased to detect about 0.8 nW/cm2 while maintaining 70 fps. The chip was used to image single cell fluorescence at 28 fps with an average SNR of 32 dB. For comparison, a cooled CCD camera imaged the same cell at 20 fps with an average SNR of 33.2 dB under the same illumination while consuming over a watt. PMID:23136624

  19. Active pixel sensor pixel having a photodetector whose output is coupled to an output transistor gate

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R. (Inventor); Nakamura, Junichi (Inventor); Kemeny, Sabrina E. (Inventor)

    2005-01-01

    An imaging device formed as a monolithic complementary metal oxide semiconductor integrated circuit in an industry standard complementary metal oxide semiconductor process, the integrated circuit including a focal plane array of pixel cells, each one of the cells including a photogate overlying the substrate for accumulating photo-generated charge in an underlying portion of the substrate and a charge coupled device section formed on the substrate adjacent the photogate having a sensing node and at least one charge coupled device stage for transferring charge from the underlying portion of the substrate to the sensing node. There is also a readout circuit, part of which can be disposed at the bottom of each column of cells and be common to all the cells in the column. A Simple Floating Gate (SFG) pixel structure could also be employed in the imager to provide a non-destructive readout and smaller pixel sizes.

  20. Single-pixel optical imaging with compressed reference intensity patterns

    NASA Astrophysics Data System (ADS)

    Chen, Wen; Chen, Xudong

    2015-03-01

    Ghost imaging with single-pixel bucket detector has attracted more and more current attention due to its marked physical characteristics. However, in ghost imaging, a large number of reference intensity patterns are usually required for object reconstruction, hence many applications based on ghost imaging (such as tomography and optical security) may be tedious since heavy storage or transmission is requested. In this paper, we report that the compressed reference intensity patterns can be used for object recovery in computational ghost imaging (with single-pixel bucket detector), and object verification can be further conducted. Only a small portion (such as 2.0% pixels) of each reference intensity pattern is used for object reconstruction, and the recovered object is verified by using nonlinear correlation algorithm. Since statistical characteristic and speckle averaging property are inherent in ghost imaging, sidelobes or multiple peaks can be effectively suppressed or eliminated in the nonlinear correlation outputs when random pixel positions are selected from each reference intensity pattern. Since pixel positions can be randomly selected from each 2D reference intensity pattern (such as total measurements of 20000), a large key space and high flexibility can be generated when the proposed method is applied for authenticationbased cryptography. When compressive sensing is used to recover the object with a small number of measurements, the proposed strategy could still be feasible through further compressing the recorded data (i.e., reference intensity patterns) followed by object verification. It is expected that the proposed method not only compresses the recorded data and facilitates the storage or transmission, but also can build up novel capability (i.e., classical or quantum information verification) for ghost imaging.

  1. Detection and compensation of bad pixel for CMOS image sensor

    NASA Astrophysics Data System (ADS)

    Xu, Youqing; Yu, Shengsheng; Zhou, Jingli; Fang, Zuyuan

    2000-05-01

    This paper presents a detailed analysis of the occurring reason and features of bad pixels in CMOS image sensor. Detect and compensate algorithms have also bee introduced. Experimental result show that the algorithms are efficiently when they are applied on CH5001 produced by Chrontel Inc.

  2. Demosaiced pixel super-resolution for multiplexed holographic color imaging

    NASA Astrophysics Data System (ADS)

    Wu, Yichen; Zhang, Yibo; Luo, Wei; Ozcan, Aydogan

    2016-06-01

    To synthesize a holographic color image, one can sequentially take three holograms at different wavelengths, e.g., at red (R), green (G) and blue (B) parts of the spectrum, and digitally merge them. To speed up the imaging process by a factor of three, a Bayer color sensor-chip can also be used to demultiplex three wavelengths that simultaneously illuminate the sample and digitally retrieve individual set of holograms using the known transmission spectra of the Bayer color filters. However, because the pixels of different channels (R, G, B) on a Bayer color sensor are not at the same physical location, conventional demosaicing techniques generate color artifacts in holographic imaging using simultaneous multi-wavelength illumination. Here we demonstrate that pixel super-resolution can be merged into the color de-multiplexing process to significantly suppress the artifacts in wavelength-multiplexed holographic color imaging. This new approach, termed Demosaiced Pixel Super-Resolution (D-PSR), generates color images that are similar in performance to sequential illumination at three wavelengths, and therefore improves the speed of holographic color imaging by 3-fold. D-PSR method is broadly applicable to holographic microscopy applications, where high-resolution imaging and multi-wavelength illumination are desired.

  3. Demosaiced pixel super-resolution for multiplexed holographic color imaging

    PubMed Central

    Wu, Yichen; Zhang, Yibo; Luo, Wei; Ozcan, Aydogan

    2016-01-01

    To synthesize a holographic color image, one can sequentially take three holograms at different wavelengths, e.g., at red (R), green (G) and blue (B) parts of the spectrum, and digitally merge them. To speed up the imaging process by a factor of three, a Bayer color sensor-chip can also be used to demultiplex three wavelengths that simultaneously illuminate the sample and digitally retrieve individual set of holograms using the known transmission spectra of the Bayer color filters. However, because the pixels of different channels (R, G, B) on a Bayer color sensor are not at the same physical location, conventional demosaicing techniques generate color artifacts in holographic imaging using simultaneous multi-wavelength illumination. Here we demonstrate that pixel super-resolution can be merged into the color de-multiplexing process to significantly suppress the artifacts in wavelength-multiplexed holographic color imaging. This new approach, termed Demosaiced Pixel Super-Resolution (D-PSR), generates color images that are similar in performance to sequential illumination at three wavelengths, and therefore improves the speed of holographic color imaging by 3-fold. D-PSR method is broadly applicable to holographic microscopy applications, where high-resolution imaging and multi-wavelength illumination are desired. PMID:27353242

  4. Single pixel optical imaging using a scanning MEMS mirror

    NASA Astrophysics Data System (ADS)

    Li, Li; Stankovic, Vladimir; Stankovic, Lina; Li, Lijie; Cheng, Samuel; Uttamchandani, Deepak

    2011-02-01

    The paper describes a low-complexity optical imaging system using demagnifying optics, a single scanning MEMS mirror and a single photodetector. Light at visible wavelengths from the object passes through a lens assembly and is incident on a scanning MEMS micromirror. After reflection from the micromirror, a complete image of the object is projected at the image plane of the optical system where a single-element photodetector with a pinhole at its entrance is located. By tilting the micromirror in the x and y directions, the projected image is translated across the image plane in the x and y directions. The photodetector sequentially detects the intensity of different areas of the projected optical image, thereby enabling a digital image to be generated pixel-by-pixel. However, due to the noisy raw image obtained experimentally, an image enhancement algorithm based on iterative-combined wavelet and curvelet denoising has been developed. Using blind image quality indices (BIQI) as an objective performance measure, it is shown that the proposed image enhancement method enhances the raw image by up to 40% and outperforms state-of-the-art denoising methods for up to 10 units of BIQI.

  5. Distance measurement based on pixel variation of CCD images.

    PubMed

    Hsu, Chen-Chien; Lu, Ming-Chih; Wang, Wei-Yen; Lu, Yin-Yu

    2009-10-01

    This paper presents a distance measurement method based on pixel number variation of CCD images by referencing to two arbitrarily designated points in the image frames. By establishing a relationship between the displacement of the camera movement along the photographing direction and the difference in pixel count between reference points in the images, the distance from an object can be calculated via the proposed method. To integrate the measuring functions into digital cameras, a circuit design implementing the proposed measuring system in selecting reference points, measuring distance, and displaying measurement results on CCD panel of the digital camera is proposed in this paper. In comparison to pattern recognition or image analysis methods, the proposed measuring approach is simple and straightforward for practical implementation into digital cameras. To validate the performance of the proposed method, measurement results using the proposed method and ultrasonic rangefinders are also presented in this paper.

  6. Imaging by photon counting with 256x256 pixel matrix

    NASA Astrophysics Data System (ADS)

    Tlustos, Lukas; Campbell, Michael; Heijne, Erik H. M.; Llopart, Xavier

    2004-09-01

    Using 0.25µm standard CMOS we have developed 2-D semiconductor matrix detectors with sophisticated functionality integrated inside each pixel of a hybrid sensor module. One of these sensor modules is a matrix of 256x256 square 55µm pixels intended for X-ray imaging. This device is called 'Medipix2' and features a fast amplifier and two-level discrimination for signals between 1000 and 100000 equivalent electrons, with overall signal noise ~150 e- rms. Signal polarity and comparator thresholds are programmable. A maximum count rate of nearly 1 MHz per pixel can be achieved, which corresponds to an average flux of 3x10exp10 photons per cm2. The selected signals can be accumulated in each pixel in a 13-bit register. The serial readout takes 5-10 ms. A parallel readout of ~300 µs could also be used. Housekeeping functions such as local dark current compensation, test pulse generation, silencing of noisy pixels and threshold tuning in each pixel contribute to the homogeneous response over a large sensor area. The sensor material can be adapted to the energy of the X-rays. Best results have been obtained with high-resistivity silicon detectors, but also CdTe and GaAs detectors have been used. The lowest detectable X-ray energy was about 4 keV. Background measurements have been made, as well as measurements of the uniformity of imaging by photon counting. Very low photon count rates are feasible and noise-free at room temperature. The readout matrix can be used also with visible photons if an energy or charge intensifier structure is interposed such as a gaseous amplification layer or a microchannel plate or acceleration field in vacuum.

  7. Sub-pixel resolution with the Multispectral Thermal Imager (MTI).

    SciTech Connect

    Decker, Max Louis; Smith, Jody Lynn; Nandy, Prabal

    2003-06-01

    The Multispectral Thermal Imager Satellite (MTI) has been used to test a sub-pixel sampling technique in an effort to obtain higher spatial frequency imagery than that of its original design. The MTI instrument is of particular interest because of its infrared detectors. In this spectral region, the detector size is traditionally the limiting factor in determining the satellite's ground sampling distance (GSD). Additionally, many over-sampling techniques require flexible command and control of the sensor and spacecraft. The MTI sensor is well suited for this task, as it is the only imaging system on the MTI satellite bus. In this super-sampling technique, MTI is maneuvered such that the data are collected at sub-pixel intervals on the ground. The data are then processed using a deconvolution algorithm using in-scene measured point spread functions (PSF) to produce an image with synthetically-boosted GSD.

  8. Image steganography using layered pixel-value differencing

    NASA Astrophysics Data System (ADS)

    Kim, Jaeyoung; Park, Hanhoon

    2017-02-01

    This paper proposes a layered approach to improve the embedding capacity of the existing pixel-value differencing (PVD) methods for image steganography. Specifically, one of the PVD methods is applied to embed a secret information into a cover image and the resulting image, called stego-image, is used to embed additional secret information by the same or another PVD method. This results in a double-layered stego-image. Then, another PVD method can be applied to the double-layered stego-image, resulting in a triple-layered stego-image. Likewise, multi-layered stego-images can be obtained. To successfully recover the secret information hidden in each layer, the embedding process is carefully designed. In the experiment, the proposed layered PVD method proved to be effective.

  9. Decoding brain responses to pixelized images in the primary visual cortex: implications for visual cortical prostheses.

    PubMed

    Guo, Bing-Bing; Zheng, Xiao-Lin; Lu, Zhen-Gang; Wang, Xing; Yin, Zheng-Qin; Hou, Wen-Sheng; Meng, Ming

    2015-10-01

    Visual cortical prostheses have the potential to restore partial vision. Still limited by the low-resolution visual percepts provided by visual cortical prostheses, implant wearers can currently only "see" pixelized images, and how to obtain the specific brain responses to different pixelized images in the primary visual cortex (the implant area) is still unknown. We conducted a functional magnetic resonance imaging experiment on normal human participants to investigate the brain activation patterns in response to 18 different pixelized images. There were 100 voxels in the brain activation pattern that were selected from the primary visual cortex, and voxel size was 4 mm × 4 mm × 4 mm. Multi-voxel pattern analysis was used to test if these 18 different brain activation patterns were specific. We chose a Linear Support Vector Machine (LSVM) as the classifier in this study. The results showed that the classification accuracies of different brain activation patterns were significantly above chance level, which suggests that the classifier can successfully distinguish the brain activation patterns. Our results suggest that the specific brain activation patterns to different pixelized images can be obtained in the primary visual cortex using a 4 mm × 4 mm × 4 mm voxel size and a 100-voxel pattern.

  10. Sub-pixel localization of highways in AVIRIS images

    NASA Technical Reports Server (NTRS)

    Salu, Yehuda

    1995-01-01

    Roads and highways show up clearly in many bands of AVIRIS images. A typical lane in the U.S. is 12 feet wide, and the total width of a four lane highway, including 18 feet of paved shoulders, is 19.8 m. Such a highway will cover only a portion of any 20x20 m AVIRIS pixel that it traverses. The other portion of these pixels wil be usually covered by vegetation. An interesting problem is to precisely determine the location of a highway within the AVIRIS pixels that it traverses. This information may be used for alignment and spatial calibration of AVIRIS images. Also, since the reflection properties of highway surfaces do not change with time, and they can be determined once and for all, such information can be of help in calculating and filtering out the atmospheric noise that contaminates AVIRIS measurements. The purpose of this report is to describe a method for sub-pixel localization of highways.

  11. Hexagonal Pixels and Indexing Scheme for Binary Images

    NASA Technical Reports Server (NTRS)

    Johnson, Gordon G.

    2004-01-01

    A scheme for resampling binaryimage data from a rectangular grid to a regular hexagonal grid and an associated tree-structured pixel-indexing scheme keyed to the level of resolution have been devised. This scheme could be utilized in conjunction with appropriate image-data-processing algorithms to enable automated retrieval and/or recognition of images. For some purposes, this scheme is superior to a prior scheme that relies on rectangular pixels: one example of such a purpose is recognition of fingerprints, which can be approximated more closely by use of line segments along hexagonal axes than by line segments along rectangular axes. This scheme could also be combined with algorithms for query-image-based retrieval of images via the Internet. A binary image on a rectangular grid is generated by raster scanning or by sampling on a stationary grid of rectangular pixels. In either case, each pixel (each cell in the rectangular grid) is denoted as either bright or dark, depending on whether the light level in the pixel is above or below a prescribed threshold. The binary data on such an image are stored in a matrix form that lends itself readily to searches of line segments aligned with either or both of the perpendicular coordinate axes. The first step in resampling onto a regular hexagonal grid is to make the resolution of the hexagonal grid fine enough to capture all the binaryimage detail from the rectangular grid. In practice, this amounts to choosing a hexagonal-cell width equal to or less than a third of the rectangular- cell width. Once the data have been resampled onto the hexagonal grid, the image can readily be checked for line segments aligned with the hexagonal coordinate axes, which typically lie at angles of 30deg, 90deg, and 150deg with respect to say, the horizontal rectangular coordinate axis. Optionally, one can then rotate the rectangular image by 90deg, then again sample onto the hexagonal grid and check for line segments at angles of 0deg, 60deg

  12. A metamaterial-based single pixel imaging system (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Padilla, Willie J.

    2016-09-01

    Electromagnetic metamaterials have demonstrated unprecedented control over light matter interactions and have realized exotic responses difficult to achieve with natural materials. The ability to achieve real-time control of novel responses exhibited by electromagnetic metamaterials has led to the realization of metadevices and metasystems. Here we experimentally demonstrate two realizations of single pixel imaging systems that rely entirely on all-electronic metamaterial spatial light modulators. The metasystem enables images to be digitally encoded with various measurement matrix coefficients, thus permitting high speed and fidelity imaging.

  13. Hyperspectral imaging using the single-pixel Fourier transform technique

    NASA Astrophysics Data System (ADS)

    Jin, Senlin; Hui, Wangwei; Wang, Yunlong; Huang, Kaicheng; Shi, Qiushuai; Ying, Cuifeng; Liu, Dongqi; Ye, Qing; Zhou, Wenyuan; Tian, Jianguo

    2017-03-01

    Hyperspectral imaging technology is playing an increasingly important role in the fields of food analysis, medicine and biotechnology. To improve the speed of operation and increase the light throughput in a compact equipment structure, a Fourier transform hyperspectral imaging system based on a single-pixel technique is proposed in this study. Compared with current imaging spectrometry approaches, the proposed system has a wider spectral range (400–1100 nm), a better spectral resolution (1 nm) and requires fewer measurement data (a sample rate of 6.25%). The performance of this system was verified by its application to the non-destructive testing of potatoes.

  14. Hyperspectral imaging using the single-pixel Fourier transform technique

    PubMed Central

    Jin, Senlin; Hui, Wangwei; Wang, Yunlong; Huang, Kaicheng; Shi, Qiushuai; Ying, Cuifeng; Liu, Dongqi; Ye, Qing; Zhou, Wenyuan; Tian, Jianguo

    2017-01-01

    Hyperspectral imaging technology is playing an increasingly important role in the fields of food analysis, medicine and biotechnology. To improve the speed of operation and increase the light throughput in a compact equipment structure, a Fourier transform hyperspectral imaging system based on a single-pixel technique is proposed in this study. Compared with current imaging spectrometry approaches, the proposed system has a wider spectral range (400–1100 nm), a better spectral resolution (1 nm) and requires fewer measurement data (a sample rate of 6.25%). The performance of this system was verified by its application to the non-destructive testing of potatoes. PMID:28338100

  15. Nano-fabricated pixelated micropolarizer array for visible imaging polarimetry

    SciTech Connect

    Zhang, Zhigang; Cheng, Teng; Qiu, Kang; Zhang, Qingchuan E-mail: wgchu@nanoctr.cn; Wu, Xiaoping; Dong, Fengliang; Chu, Weiguo E-mail: wgchu@nanoctr.cn

    2014-10-15

    Pixelated micropolarizer array (PMA) is a novel concept for real-time visible imaging polarimetry. A 320 × 240 aluminum PMA fabricated by electron beam lithography is described in this paper. The period, duty ratio, and depth of the grating are 140 nm, 0.5, and 100 nm, respectively. The units are standard square structures and the metal nanowires of the grating are collimating and uniformly thick. The extinction ratio of 75 and the maximum polarization transmittance of 78.8% demonstrate that the PMA is suitable for polarization imaging. When the PMA is applied to real-time polarization imaging, the degree of linear polarization image and the angle of linear polarization image are calculated from a single frame image. The polarized target object is highlighted from the unpolarized background, and the surface contour of the target object can be reflected by the polarization angle.

  16. Spectroscopic and imaging capabilities of a pixellated photon counting system

    NASA Astrophysics Data System (ADS)

    Amendolia, S. R.; Bisogni, M. G.; Bottigli, U.; Delogu, P.; Dipasquale, G.; Fantacci, M. E.; Marchi, A.; Marzulli, V. M.; Oliva, P.; Palmiero, R.; Rosso, V.; Stefanini, A.; Stumbo, S.; Zucca, S.

    2001-06-01

    We are studying the performance of various thickness GaAs pixel detectors bump-bonded to a dedicated photon counting chip (PCC) for medical imaging applications in different energy ranges. In this work we present the experimental results obtained with a 600 μm thick pixel matrix (64×64 square pixels, 170 μm side) in the 60-140 keV energy range to evaluate the possible use of such a system in the nuclear medicine field. In particular, we have measured the spectroscopic properties of the detector (charge collection efficiency, energy resolution and detection efficiency) and evaluated the discrimination capability of the electronics. Then we have measured the imaging properties of the whole system in terms of Point Spread Function and using a home made thyroid phantom. We present also a comparison with a traditional gamma camera and an evaluation, made by both experimental measurements and software simulations, of the imaging characteristics related to the use of a collimation system.

  17. Analysis of filtering techniques and image quality in pixel duplicated images

    NASA Astrophysics Data System (ADS)

    Mehrubeoglu, Mehrube; McLauchlan, Lifford

    2009-08-01

    When images undergo filtering operations, valuable information can be lost besides the intended noise or frequencies due to averaging of neighboring pixels. When the image is enlarged by duplicating pixels, such filtering effects can be reduced and more information retained, which could be critical when analyzing image content automatically. Analysis of retinal images could reveal many diseases at early stage as long as minor changes that depart from a normal retinal scan can be identified and enhanced. In this paper, typical filtering techniques are applied to an early stage diabetic retinopathy image which has undergone digital pixel duplication. The same techniques are applied to the original images for comparison. The effects of filtering are then demonstrated for both pixel duplicated and original images to show the information retention capability of pixel duplication. Image quality is computed based on published metrics. Our analysis shows that pixel duplication is effective in retaining information on smoothing operations such as mean filtering in the spatial domain, as well as lowpass and highpass filtering in the frequency domain, based on the filter window size. Blocking effects due to image compression and pixel duplication become apparent in frequency analysis.

  18. Using an Active Pixel Sensor In A Vertex Detector

    SciTech Connect

    Matis, Howard S.; Bieser, Fred; Chen, Yandong; Gareus, Robin; Kleinfelder, Stuart; Oldenburg, Markus; Retiere, Fabrice; Ritter, HansGeorg; Wieman, Howard H.; Wurzel, Samuel E.; Yamamoto, Eugene

    2004-04-22

    Research has shown that Active Pixel CMOS sensors can detect charged particles. We have been studying whether this process can be used in a collider environment. In particular, we studied the effect of radiation with 55 MeV protons. These results show that a fluence of about 2 x 10{sup 12} protons/cm{sup 2} reduces the signal by a factor of two while the noise increases by 25%. A measurement 6 months after exposure shows that the silicon lattice naturally repairs itself. Heating the silicon to 100 C reduced the shot noise and increased the collected charge. CMOS sensors have a reduced signal to noise ratio per pixel because charge diffuses to neighboring pixels. We have constructed a photogate to see if this structure can collect more charge per pixel. Results show that a photogate does collect charge in fewer pixels, but it takes about 15 ms to collect all of the electrons produced by a pulse of light.

  19. Multilayer fluorescence imaging on a single-pixel detector

    PubMed Central

    Guo, Kaikai; Jiang, Shaowei; Zheng, Guoan

    2016-01-01

    A critical challenge for fluorescence imaging is the loss of high frequency components in the detection path. Such a loss can be related to the limited numerical aperture of the detection optics, aberrations of the lens, and tissue turbidity. In this paper, we report an imaging scheme that integrates multilayer sample modeling, ptychography-inspired recovery procedures, and lensless single-pixel detection to tackle this challenge. In the reported scheme, we directly placed a 3D sample on top of a single-pixel detector. We then used a known mask to generate speckle patterns in 3D and scanned this known mask to different positions for sample illumination. The sample was then modeled as multiple layers and the captured 1D fluorescence signals were used to recover multiple sample images along the z axis. The reported scheme may find applications in 3D fluorescence sectioning, time-resolved and spectrum-resolved imaging. It may also find applications in deep-tissue fluorescence imaging using the memory effect. PMID:27446679

  20. Multilayer fluorescence imaging on a single-pixel detector.

    PubMed

    Guo, Kaikai; Jiang, Shaowei; Zheng, Guoan

    2016-07-01

    A critical challenge for fluorescence imaging is the loss of high frequency components in the detection path. Such a loss can be related to the limited numerical aperture of the detection optics, aberrations of the lens, and tissue turbidity. In this paper, we report an imaging scheme that integrates multilayer sample modeling, ptychography-inspired recovery procedures, and lensless single-pixel detection to tackle this challenge. In the reported scheme, we directly placed a 3D sample on top of a single-pixel detector. We then used a known mask to generate speckle patterns in 3D and scanned this known mask to different positions for sample illumination. The sample was then modeled as multiple layers and the captured 1D fluorescence signals were used to recover multiple sample images along the z axis. The reported scheme may find applications in 3D fluorescence sectioning, time-resolved and spectrum-resolved imaging. It may also find applications in deep-tissue fluorescence imaging using the memory effect.

  1. MONOLITHIC ACTIVE PIXEL MATRIX WITH BINARY COUNTERS IN AN SOI PROCESS.

    SciTech Connect

    DUPTUCH,G.; YAREMA, R.

    2007-06-07

    The design of a Prototype monolithic active pixel matrix, designed in a 0.15 {micro}m CMOS SOI Process, is presented. The process allowed connection between the electronics and the silicon volume under the layer of buried oxide (BOX). The small size vias traversing through the BOX and implantation of small p-type islands in the n-type bulk result in a monolithic imager. During the acquisition time, all pixels register individual radiation events incrementing the counters. The counting rate is up to 1 MHz per pixel. The contents of counters are shifted out during the readout phase. The designed prototype is an array of 64 x 64 pixels and the pixel size is 26 x 26 {micro}m{sup 2}.

  2. Microlens performance limits in sub-2mum pixel CMOS image sensors.

    PubMed

    Huo, Yijie; Fesenmaier, Christian C; Catrysse, Peter B

    2010-03-15

    CMOS image sensors with smaller pixels are expected to enable digital imaging systems with better resolution. When pixel size scales below 2 mum, however, diffraction affects the optical performance of the pixel and its microlens, in particular. We present a first-principles electromagnetic analysis of microlens behavior during the lateral scaling of CMOS image sensor pixels. We establish for a three-metal-layer pixel that diffraction prevents the microlens from acting as a focusing element when pixels become smaller than 1.4 microm. This severely degrades performance for on and off-axis pixels in red, green and blue color channels. We predict that one-metal-layer or backside-illuminated pixels are required to extend the functionality of microlenses beyond the 1.4 microm pixel node.

  3. A New Pixels Flipping Method for Huge Watermarking Capacity of the Invoice Font Image

    PubMed Central

    Li, Li; Hou, Qingzheng; Lu, Jianfeng; Dai, Junping; Mao, Xiaoyang; Chang, Chin-Chen

    2014-01-01

    Invoice printing just has two-color printing, so invoice font image can be seen as binary image. To embed watermarks into invoice image, the pixels need to be flipped. The more huge the watermark is, the more the pixels need to be flipped. We proposed a new pixels flipping method in invoice image for huge watermarking capacity. The pixels flipping method includes one novel interpolation method for binary image, one flippable pixels evaluation mechanism, and one denoising method based on gravity center and chaos degree. The proposed interpolation method ensures that the invoice image keeps features well after scaling. The flippable pixels evaluation mechanism ensures that the pixels keep better connectivity and smoothness and the pattern has highest structural similarity after flipping. The proposed denoising method makes invoice font image smoother and fiter for human vision. Experiments show that the proposed flipping method not only keeps the invoice font structure well but also improves watermarking capacity. PMID:25489606

  4. Solution processed integrated pixel element for an imaging device

    NASA Astrophysics Data System (ADS)

    Swathi, K.; Narayan, K. S.

    2016-09-01

    We demonstrate the implementation of a solid state circuit/structure comprising of a high performing polymer field effect transistor (PFET) utilizing an oxide layer in conjunction with a self-assembled monolayer (SAM) as the dielectric and a bulk-heterostructure based organic photodiode as a CMOS-like pixel element for an imaging sensor. Practical usage of functional organic photon detectors requires on chip components for image capture and signal transfer as in the CMOS/CCD architecture rather than simple photodiode arrays in order to increase speed and sensitivity of the sensor. The availability of high performing PFETs with low operating voltage and photodiodes with high sensitivity provides the necessary prerequisite to implement a CMOS type image sensing device structure based on organic electronic devices. Solution processing routes in organic electronics offers relatively facile procedures to integrate these components, combined with unique features of large-area, form factor and multiple optical attributes. We utilize the inherent property of a binary mixture in a blend to phase-separate vertically and create a graded junction for effective photocurrent response. The implemented design enables photocharge generation along with on chip charge to voltage conversion with performance parameters comparable to traditional counterparts. Charge integration analysis for the passive pixel element using 2D TCAD simulations is also presented to evaluate the different processes that take place in the monolithic structure.

  5. Bilateral bad pixel and Stokes image reconstruction for microgrid polarimetric imagers

    NASA Astrophysics Data System (ADS)

    LeMaster, Daniel A.; Ratliff, Bradley M.

    2015-09-01

    Uncorrected or poorly corrected bad pixels reduce the effectiveness of polarimetric clutter suppression. In conventional microgrid processing, bad pixel correction is accomplished as a separate step from Stokes image reconstruction. Here, these two steps are combined to speed processing and provide better estimates of the entire image, including missing samples. A variation on the bilateral filter enables both edge preservation in the Stokes imagery and bad pixel suppression. Understanding the newly presented filter requires two key insights. First, the adaptive nature of the bilateral filter is extended to correct for bad pixels by simply incorporating a bad pixel mask. Second, the bilateral filter for Stokes estimation is the sum of the normalized bilateral filters for estimating each analyzer channel individually. This paper describes the new approach and compares it to our legacy method using simulated imagery.

  6. Efficient defect pixel cluster detection and correction for Bayer CFA image sequences

    NASA Astrophysics Data System (ADS)

    Tajbakhsh, Touraj

    2011-01-01

    Image sensor arrays may have defect pixels, either originating from manufacturing or being developed over the lifetime of the image sensor array. Continuous defect pixel detection and correction performing during camera runtime is desirable. On-the-fly detection and correction is challenging since edges and high-frequency image content might get identified as defect pixel regions and intact pixels become corrupted during defect pixel replacement. We propose a table-based detection and correction method which by and by fills the non-volatile table during normal camera operation. In this work we model defect pixels and pixel clusters to be stuck to fixed values or at least fixed to a narrow value range whereas the local neighborhood of these pixels indicate a normal behavior. The idea is to temporally observe the value ranges of small group of pixels (e.g. 4x4 pixel blocks) and to decide about their defective condition depending on their variability with respect to their neighbor pixels. Our method is computationally efficient, requires no frame buffer, requires modest memory, and therefore is appropriate to operate in line-buffer based image signal processing (ISP) systems. Our results indicate high reliability in terms of detection rates and robustness against high-frequency image content. As part of the defect pixel replacement system we also propose a simple and efficient defect pixel correction method based on the mean of medians operating on the Bayer CFA image domain.

  7. Probability Distribution Estimation for Autoregressive Pixel-Predictive Image Coding.

    PubMed

    Weinlich, Andreas; Amon, Peter; Hutter, Andreas; Kaup, André

    2016-03-01

    Pixelwise linear prediction using backward-adaptive least-squares or weighted least-squares estimation of prediction coefficients is currently among the state-of-the-art methods for lossless image compression. While current research is focused on mean intensity prediction of the pixel to be transmitted, best compression requires occurrence probability estimates for all possible intensity values. Apart from common heuristic approaches, we show how prediction error variance estimates can be derived from the (weighted) least-squares training region and how a complete probability distribution can be built based on an autoregressive image model. The analysis of image stationarity properties further allows deriving a novel formula for weight computation in weighted least-squares proofing and generalizing ad hoc equations from the literature. For sparse intensity distributions in non-natural images, a modified image model is presented. Evaluations were done in the newly developed C++ framework volumetric, artificial, and natural image lossless coder (Vanilc), which can compress a wide range of images, including 16-bit medical 3D volumes or multichannel data. A comparison with several of the best available lossless image codecs proofs that the method can achieve very competitive compression ratios. In terms of reproducible research, the source code of Vanilc has been made public.

  8. Noncolorimetric measurement of cell activity in three-dimensional histoculture using the tetrazolium dye 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide: the pixel image analysis of formazan crystals.

    PubMed

    Colangelo, D; Guo, H Y; Connors, K M; Silvestro, L; Hoffman, R M

    1992-08-15

    We describe a novel system for measuring the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction in three-dimensional histoculture which is no longer dependent on colorimetric determination of extracted formazan, but rather is based on a pixel image analysis of formazan crystals, and which allows intratumor heterogeneity to be taken into account. The MTT test is based on the enzymatic reduction of the tetrazolium salt 3-(4,5-dimethylthiazol-2-yl)-2,5-dipheniltetrazolium bromide to formazan crystals by living, metabolically active cells, but not in dead cells. The reaction was carried out in situ in six-well plates on gel-supported histocultured human tumors. After a 24-h incubation with different drugs the tumors were incubated with a solution of MTT. Frozen sections of the tumor pieces were made and the slides were then stained with a propidium iodide solution, whose fluorescence is proportional to the number of cells present. We demonstrate here that the formazan crystals, formed by MTT reduction, reflect polarized light and that this can be quantified by using an image analysis system based on bright-pixel quantitation directly on a frozen section of the original tissue. Combined with the use of the fluorescent dye propidium iodide, also measured by pixel analysis, we can express a ratio between the total amount of MTT reduction and the total number of cells present in the specimen that expresses the effect of drugs on the histocultured tumors. Since histology is well maintained in histoculture it is possible to take into account the heterogeneity present in the tumor with regard to drug response.(ABSTRACT TRUNCATED AT 250 WORDS)

  9. Error analysis of filtering operations in pixel-duplicated images of diabetic retinopathy

    NASA Astrophysics Data System (ADS)

    Mehrubeoglu, Mehrube; McLauchlan, Lifford

    2010-08-01

    In this paper, diabetic retinopathy is chosen for a sample target image to demonstrate the effectiveness of image enlargement through pixel duplication in identifying regions of interest. Pixel duplication is presented as a simpler alternative to data interpolation techniques for detecting small structures in the images. A comparative analysis is performed on different image processing schemes applied to both original and pixel-duplicated images. Structures of interest are detected and and classification parameters optimized for minimum false positive detection in the original and enlarged retinal pictures. The error analysis demonstrates the advantages as well as shortcomings of pixel duplication in image enhancement when spatial averaging operations (smoothing filters) are also applied.

  10. Pixel detectors for x-ray imaging spectroscopy in space

    NASA Astrophysics Data System (ADS)

    Treis, J.; Andritschke, R.; Hartmann, R.; Herrmann, S.; Holl, P.; Lauf, T.; Lechner, P.; Lutz, G.; Meidinger, N.; Porro, M.; Richter, R. H.; Schopper, F.; Soltau, H.; Strüder, L.

    2009-03-01

    Pixelated semiconductor detectors for X-ray imaging spectroscopy are foreseen as key components of the payload of various future space missions exploring the x-ray sky. Located on the platform of the new Spectrum-Roentgen-Gamma satellite, the eROSITA (extended Roentgen Survey with an Imaging Telescope Array) instrument will perform an imaging all-sky survey up to an X-ray energy of 10 keV with unprecedented spectral and angular resolution. The instrument will consist of seven parallel oriented mirror modules each having its own pnCCD camera in the focus. The satellite born X-ray observatory SIMBOL-X will be the first mission to use formation-flying techniques to implement an X-ray telescope with an unprecedented focal length of around 20 m. The detector instrumentation consists of separate high- and low energy detectors, a monolithic 128 × 128 DEPFET macropixel array and a pixellated CdZTe detector respectively, making energy band between 0.5 to 80 keV accessible. A similar concept is proposed for the next generation X-ray observatory IXO. Finally, the MIXS (Mercury Imaging X-ray Spectrometer) instrument on the European Mercury exploration mission BepiColombo will use DEPFET macropixel arrays together with a small X-ray telescope to perform a spatially resolved planetary XRF analysis of Mercury's crust. Here, the mission concepts and their scientific targets are briefly discussed, and the resulting requirements on the detector devices together with the implementation strategies are shown.

  11. Electron Pattern Recognition using trigger mode SOI pixel sensor for Advanced Compton Imaging

    NASA Astrophysics Data System (ADS)

    Shimazoe, K.; Yoshihara, Y.; Fairuz, A.; Koyama, A.; Takahashi, H.; Takeda, A.; Tsuru, T.; Arai, Y.

    2016-02-01

    Compton imaging is a useful method for localizing sub MeV to a few MeV gamma-rays and widely used for environmental and medical applications. The direction of recoiled electrons in Compton scattering process provides the additional information to limit the Compton cones and increases the sensitivity in the system. The capability of recoiled electron tracking using trigger-mode Silicon-On-Insulator (SOI) sensor is investigated with various radiation sources. The trigger-mode SOI sensor consists of 144 by 144 active pixels with 30 μm cells and the thickness of sensor is 500 μm. The sensor generates the digital output when it is hit by gamma-rays and 25 by 25 pixel pattern of surrounding the triggered pixel is readout to extract the recoiled electron track. The electron track is successfully observed for 60Co and 137Cs sources, which provides useful information for future electron tracking Compton camera.

  12. Non-mechanical sub-pixel image shifter for acquiring super-resolution digital images.

    PubMed

    Lan, Hsiao-Chin; Wu, Mount-Learn; Yeatman, Eric M

    2009-12-07

    A sub-pixel image shifter is presented, for use in enhancing the spatial resolution of digital image sensors by combining multiple displaced sub-images using a super-resolution (SR) algorithm. The device uses the walk-off phenomenon in birefringent crystals to separate images with opposite polarizations by a sub-pixel displacement. A liquid crystal (LC) waveplate plus a polarizer can then select the specific image to be exposed, with fast, non-mechanical control. This cascaded device, comprising two sapphire crystals, two LCs, and a single polarizer, is capable of 2-dimensional image shift with displacements of 0.5 pixels. The experimental results show that the image registration stability can be precisely controlled within 0.05 pixels and the contrast transfer function ratio of the SR image is enhanced by up to 1.36 times compared to the original captured image. Moreover, based on the fast transition time of LCs, the displaced sub-images can be recorded in video form with a frame rate of 40 fps.

  13. Edge effects in a small pixel CdTe for X-ray imaging

    NASA Astrophysics Data System (ADS)

    Duarte, D. D.; Bell, S. J.; Lipp, J.; Schneider, A.; Seller, P.; Veale, M. C.; Wilson, M. D.; Baker, M. A.; Sellin, P. J.; Kachkanov, V.; Sawhney, K. J. S.

    2013-10-01

    Large area detectors capable of operating with high detection efficiency at energies above 30 keV are required in many contemporary X-ray imaging applications. The properties of high Z compound semiconductors, such as CdTe, make them ideally suitable to these applications. The STFC Rutherford Appleton Laboratory has developed a small pixel CdTe detector with 80 × 80 pixels on a 250 μm pitch. Historically, these detectors have included a 200 μm wide guard band around the pixelated anode to reduce the effect of defects in the crystal edge. The latest version of the detector ASIC is capable of four-side butting that allows the tiling of N × N flat panel arrays. To limit the dead space between modules to the width of one pixel, edgeless detector geometries have been developed where the active volume of the detector extends to the physical edge of the crystal. The spectroscopic performance of an edgeless CdTe detector bump bonded to the HEXITEC ASIC was tested with sealed radiation sources and compared with a monochromatic X-ray micro-beam mapping measurements made at the Diamond Light Source, U.K. The average energy resolution at 59.54 keV of bulk and edge pixels was 1.23 keV and 1.58 keV, respectively. 87% of the edge pixels present fully spectroscopic performance demonstrating that edgeless CdTe detectors are a promising technology for the production of large panel radiation detectors for X-ray imaging.

  14. Development activities of a CdTe/CdZnTe pixel detector for gamma-ray spectrometry with imaging and polarimetry capability in astrophysics

    NASA Astrophysics Data System (ADS)

    Gálvez, J. L.; Hernanz, M.; Álvarez, J. M.; Álvarez, L.; La Torre, M.; Caroli, E.; Lozano, M.; Pellegrini, G.; Ullán, M.; Cabruja, E.; Martínez, R.; Chmeissani, M.; Puigdengoles, C.

    2013-05-01

    In the last few years we have been working on feasibility studies of future instruments in the gamma-ray range, from several keV up to a few MeV, in collaboration with other research institutes. High sensitivities are essential to perform detailed studies of cosmic explosions and cosmic accelerators, e.g., Supernovae, Classical Novae, Supernova Remnants (SNRs), Gamma-Ray Bursts (GRBs), Pulsars, Active Galactic Nuclei (AGN).Cadmium Telluride (CdTe) and Cadmium Zinc Telluride (CdZnTe) are very attractive materials for gamma-ray detection, since they have already demonstrated their great performance onboard current space missions, such as IBIS/INTEGRAL and BAT/SWIFT, and future projects like ASIM onboard the ISS. However, the energy coverage of these instruments is limited up to a few hundred keV, and there has not been yet a dedicated instrument for polarimetry.Our research and development activities aim to study a gamma-ray imaging spectrometer in the MeV range based on CdTe detectors, suited either for the focal plane of a focusing mission or as a calorimeter for a Compton camera. In addition, our undergoing detector design is proposed as the baseline for the payload of a balloon-borne experiment dedicated to hard X- and soft gamma-ray polarimetry, currently under study and called CμSP (CZT μ-Spectrometer Polarimeter). Other research institutes such as INAF-IASF, DTU Space, LIP, INEM/CNR, CEA, are involved in this proposal. We will report on the main features of the prototype we are developing at the Institute of Space Sciences, a gamma-ray detector with imaging and polarimetry capabilities in order to fulfil the combined requirement of high detection efficiency with good spatial and energy resolution driven by the science.

  15. Active pixel sensor having intra-pixel charge transfer with analog-to-digital converter

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R. (Inventor); Mendis, Sunetra K. (Inventor); Pain, Bedabrata (Inventor); Nixon, Robert H. (Inventor); Zhou, Zhimin (Inventor)

    2003-01-01

    An imaging device formed as a monolithic complementary metal oxide semiconductor integrated circuit in an industry standard complementary metal oxide semiconductor process, the integrated circuit including a focal plane array of pixel cells, each one of the cells including a photogate overlying the substrate for accumulating photo-generated charge in an underlying portion of the substrate, a readout circuit including at least an output field effect transistor formed in the substrate, and a charge coupled device section formed on the substrate adjacent the photogate having a sensing node connected to the output transistor and at least one charge coupled device stage for transferring charge from the underlying portion of the substrate to the sensing node and an analog-to-digital converter formed in the substrate connected to the output of the readout circuit.

  16. Active pixel sensor having intra-pixel charge transfer with analog-to-digital converter

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R. (Inventor); Mendis, Sunetra K. (Inventor); Pain, Bedabrata (Inventor); Nixon, Robert H. (Inventor); Zhou, Zhimin (Inventor)

    2000-01-01

    An imaging device formed as a monolithic complementary metal oxide semiconductor Integrated circuit in an industry standard complementary metal oxide semiconductor process, the integrated circuit including a focal plane array of pixel cells, each one of the cells including a photogate overlying the substrate for accumulating photo-generated charge in an underlying portion of the substrate, a readout circuit including at least an output field effect transistor formed in the substrate, and a charge coupled device section formed on the substrate adjacent the photogate having a sensing node connected to the output transistor and at least one charge coupled device stage for transferring charge from the underlying portion of the substrate to the sensing node and an analog-to-digital converter formed in the substrate connected to the output of the readout circuit.

  17. Pixel level image fusion for medical imaging: an energy minimizing approach

    NASA Astrophysics Data System (ADS)

    Miles, Brandon; Law, Max W. K.; Ben-Ayed, Ismail; Garvin, Greg; Fenster, Aaron; Li, Shuo

    2012-03-01

    In an attempt to improve the visualisation techniques for diagnosis and treatment of musculoskeletal injuries, we present a novel image fusion method for a pixel-wise fusion of CT and MR images. We focus on the spine and it's related diseases including osteophyte growth, degenerate disc disease and spinal stenosis. This will have benefit to the 50-75% of people who suffer from back pain, which is the reason for 1.8% of all hospital stays in the United States.1 Pre-registered CT and MR image pairs were used. Rigid registration was performed based on soft tissue correspondence. A pixel-wise image fusion algorithm has been designed to combine CT and MR images into a single image. This is accomplished by minimizing an energy functional using a Graph Cut approach. The functional is formulated to balance the similarity between the resultant image and the CT image as well as between the resultant image and the MR image. Furthermore the variational smoothness of the resultant image is considered in the energy functional (to enforce natural transitions between pixels). The results have been validated based on the amount of significant detail preserved in the final fused image. Based on bone cortex and disc / spinal cord areas, 95% of the relevant MR detail and 85% of the relevant CT detail was preserved. This work has the potential to aid in patient diagnosis, surgery planning and execution along with post operative follow up.

  18. Active pixel as dosimetric device for interventional radiology

    NASA Astrophysics Data System (ADS)

    Servoli, L.; Baldaccini, F.; Biasini, M.; Checcucci, B.; Chiocchini, S.; Cicioni, R.; Conti, E.; Di Lorenzo, R.; Dipilato, A. C.; Esposito, A.; Fanó, L.; Paolucci, M.; Passeri, D.; Pentiricci, A.; Placidi, P.

    2013-08-01

    Interventional Radiology (IR) is a subspecialty of radiology comprehensive of all minimally invasive diagnostic and therapeutic procedures performed using radiological devices to obtain image guidance. The interventional procedures are potentially harmful for interventional radiologists and medical staff due to the X-ray diffusion by the patient's body. The characteristic energy range of the diffused photons spans few tens of keV. In this work we will present a proposal for a new X-ray sensing element in the energy range of interest for IR procedures. The sensing element will then be assembled in a dosimeter prototype, capable of real-time measurement, packaged in a small form-factor, with wireless communication and no external power supply to be used for individual operators dosimetry for IR procedures. For the sensor, which is the heart of the system, we considered three different Active Pixel Sensors (APS). They have shown a good capability as single X-ray photon detectors, up to several tens keV photon energy. Two dosimetric quantities have been considered, the number of detected photons and the measured energy deposition. Both observables have a linear dependence with the dose, as measured by commercial dosimeters. The uncertainties in the measurement are dominated by statistic and can be pushed at ˜5% for all the sensors under test.

  19. Classification of multispectral image data by the Binary Diamond neural network and by nonparametric, pixel-by-pixel methods

    NASA Technical Reports Server (NTRS)

    Salu, Yehuda; Tilton, James

    1993-01-01

    The classification of multispectral image data obtained from satellites has become an important tool for generating ground cover maps. This study deals with the application of nonparametric pixel-by-pixel classification methods in the classification of pixels, based on their multispectral data. A new neural network, the Binary Diamond, is introduced, and its performance is compared with a nearest neighbor algorithm and a back-propagation network. The Binary Diamond is a multilayer, feed-forward neural network, which learns from examples in unsupervised, 'one-shot' mode. It recruits its neurons according to the actual training set, as it learns. The comparisons of the algorithms were done by using a realistic data base, consisting of approximately 90,000 Landsat 4 Thematic Mapper pixels. The Binary Diamond and the nearest neighbor performances were close, with some advantages to the Binary Diamond. The performance of the back-propagation network lagged behind. An efficient nearest neighbor algorithm, the binned nearest neighbor, is described. Ways for improving the performances, such as merging categories, and analyzing nonboundary pixels, are addressed and evaluated.

  20. Single-pixel imaging by Hadamard transform and its application for hyperspectral imaging

    NASA Astrophysics Data System (ADS)

    Mizutani, Yasuhiro; Shibuya, Kyuki; Taguchi, Hiroki; Iwata, Tetsuo; Takaya, Yasuhiro; Yasui, Takeshi

    2016-10-01

    In this paper, we report on comparisons of single-pixel imagings using Hadamard Transform (HT) and the ghost imaging (GI) in the view point of the visibility under weak light conditions. For comparing the two methods, we have discussed about qualities of images based on experimental results and numerical analysis. To detect images by the TH method, we have illuminated the Hadamard-pattern mask and calculated by orthogonal transform. On the other hand, the GH method can detect images by illuminating random patterns and a correlation measurement. For comparing two methods under weak light intensity, we have controlled illuminated intensities of a DMD projector about 0.1 in signal-to-noise ratio. Though a process speed of the HT image was faster then an image via the GI, the GI method has an advantage of detection under weak light condition. An essential difference between the HT and the GI method is discussed about reconstruction process. Finally, we also show a typical application of the single-pixel imaging such as hyperspectral images by using dual-optical frequency combs. An optical setup consists of two fiber lasers, spatial light modulated for generating patten illumination, and a single pixel detector. We are successful to detect hyperspectrul images in a range from 1545 to 1555 nm at 0.01nm resolution.

  1. Imaging performance of the hybrid pixel detectors XPAD3-S

    NASA Astrophysics Data System (ADS)

    Brunner, F. Cassol; Clemens, J. C.; Hemmer, C.; Morel, C.

    2009-03-01

    Hybrid pixel detectors, originally developed for tracking particles in high-energy physics experiments, have recently been used in material sciences and macromolecular crystallography. Their capability to count single photons and to apply a threshold on the photon energy suggests that they could be optimal digital x-ray detectors in low energy beams such as for small animal computed tomography (CT). To investigate this issue, we have studied the imaging performance of photon counting hybrid pixel detectors based on the XPAD3-S chip. Two detectors are considered, connected either to a Si or to a CdTe sensor, the latter being of interest for its higher efficiency. Both a standard 'International Electrotechnical Commission' (IEC) mammography beam and a beam used for mouse CT results published in the literature are employed. The detector stability, linearity and noise are investigated as a function of the dose for several imaging exposures (~0.1-400 µGy). The perfect linearity of both detectors is confirmed, but an increase in internal noise for counting statistics higher than ~5000 photons has been found, corresponding to exposures above ~110 µGy and ~50 µGy for the Si and CdTe sensors, respectively. The noise power spectrum (NPS), the modulation transfer function (MTF) and the detective quantum efficiency (DQE) are then measured for two energy threshold configurations (5 keV and 18 keV) and three doses (~3, 30 and 300 µGy), in order to obtain a complete estimation of the detector performances. In general, the CdTe sensor shows a clear superiority with a maximal DQE(0) of ~1, thanks to its high efficiency (~100%). The DQE of the Si sensor is more dependent on the radiation quality, due to the energy dependence of its efficiency its maximum is ~0.4 with respect to the softer radiation. Finally, we compare the XPAD3-S DQE with published curves of other digital devices in a similar radiation condition. The XPAD3-S/CdTe detector appears to be the best with the highest

  2. The effect of split pixel HDR image sensor technology on MTF measurements

    NASA Astrophysics Data System (ADS)

    Deegan, Brian M.

    2014-03-01

    Split-pixel HDR sensor technology is particularly advantageous in automotive applications, because the images are captured simultaneously rather than sequentially, thereby reducing motion blur. However, split pixel technology introduces artifacts in MTF measurement. To achieve a HDR image, raw images are captured from both large and small sub-pixels, and combined to make the HDR output. In some cases, a large sub-pixel is used for long exposure captures, and a small sub-pixel for short exposures, to extend the dynamic range. The relative size of the photosensitive area of the pixel (fill factor) plays a very significant role in the output MTF measurement. Given an identical scene, the MTF will be significantly different, depending on whether you use the large or small sub-pixels i.e. a smaller fill factor (e.g. in the short exposure sub-pixel) will result in higher MTF scores, but significantly greater aliasing. Simulations of split-pixel sensors revealed that, when raw images from both sub-pixels are combined, there is a significant difference in rising edge (i.e. black-to-white transition) and falling edge (white-to-black) reproduction. Experimental results showed a difference of ~50% in measured MTF50 between the falling and rising edges of a slanted edge test chart.

  3. Imaging detector development for nuclear astrophysics using pixelated CdTe

    NASA Astrophysics Data System (ADS)

    Álvarez, J. M.; Gálvez, J. L.; Hernanz, M.; Isern, J.; Llopis, M.; Lozano, M.; Pellegrini, G.; Chmeissani, M.

    2010-11-01

    The concept of focusing telescopes in the energy range of lines of astrophysical interest (i.e., of energies around 1 MeV) should allow to reach unprecedented sensitivities, essential to perform detailed studies of cosmic explosions and cosmic accelerators. Our research and development activities aim to study a detector suited for the focal plane of a γ-ray telescope mission. A CdTe/CdZnTe detector operating at room temperature, that combines high detection efficiency with good spatial and spectral resolution is being studied in recent years as a focal plane detector, with the interesting option of also operating as a Compton telescope monitor. We present the current status of the design and development of a γ-ray imaging spectrometer in the MeV range, for nuclear astrophysics, consisting of a stack of CdTe pixel detectors with increasing thicknesses. We have developed an initial prototype based on CdTe ohmic detector. The detector has 11×11 pixels, with a pixel pitch of 1 mm and a thickness of 2 mm. Each pixel is stud bonded to a fanout board and routed to an front end ASIC to measure pulse height and rise time information for each incident γ-ray photon. First measurements of a 133Ba and 241Am source are reported here.

  4. Missing pixels restoration for remote sensing images using adaptive search window and linear regression

    NASA Astrophysics Data System (ADS)

    Tai, Shen-Chuan; Chen, Peng-Yu; Chao, Chian-Yen

    2016-07-01

    The Consultative Committee for Space Data Systems proposed an efficient image compression standard that can do lossless compression (CCSDS-ICS). CCSDS-ICS is the most widely utilized standard for satellite communications. However, the original CCSDS-ICS is weak in terms of error resilience with even a single incorrect bit possibly causing numerous missing pixels. A restoration algorithm based on the neighborhood similar pixel interpolator is proposed to fill in missing pixels. The linear regression model is used to generate the reference image from other panchromatic or multispectral images. Furthermore, an adaptive search window is utilized to sieve out similar pixels from the pixels in the search region defined in the neighborhood similar pixel interpolator. The experimental results show that the proposed methods are capable of reconstructing missing regions with good visual quality.

  5. Shape determination of microcalcifications in simulated digital mammography images with varying pixel size

    NASA Astrophysics Data System (ADS)

    Ruschin, Mark; Bath, Magnus; Hemdal, Bengt; Tingberg, Anders

    2005-04-01

    The purpose of this work was to study how the pixel size of digital detectors can affect shape determination of microcalcifications in mammography. Screen-film mammograms containing microcalcifications clinically proven to be indicative of malignancy were digitised at 100 lines/mm using a high-resolution Tango drum scanner. Forty microcalcifications were selected to cover an appropriate range of sizes, shapes and contrasts typically found of malignant cases. Based on the measured MTF and NPS of the combined screen-film and scanner system, these digitised images were filtered to simulate images acquired with a square sampling pixel size of 10 μm x 10 μm and a fill factor of one. To simulate images acquired with larger pixel sizes, these finely sampled images were re-binned to yield a range of effective pixel sizes from 20 μm up to 140 μm. An alternative forced-choice (AFC) observer experiment was conducted with eleven observers for this set of digitised microcalcifications to determine how pixel size affects the ability to discriminate shape. It was found that observer score increased with decreasing pixel size down to 60 μm (p<0.01), at which point no significant advantage was obtained by using smaller pixel sizes due to the excessive relative noise-per-pixel. The relative gain in shape discrimination ability at smaller pixel sizes was larger for microcalcifications that were smaller than 500 μm and circular.

  6. Three-dimensional cascaded system analysis of a 50 µm pixel pitch wafer-scale CMOS active pixel sensor x-ray detector for digital breast tomosynthesis

    NASA Astrophysics Data System (ADS)

    Zhao, C.; Vassiljev, N.; Konstantinidis, A. C.; Speller, R. D.; Kanicki, J.

    2017-03-01

    High-resolution, low-noise x-ray detectors based on the complementary metal-oxide-semiconductor (CMOS) active pixel sensor (APS) technology have been developed and proposed for digital breast tomosynthesis (DBT). In this study, we evaluated the three-dimensional (3D) imaging performance of a 50 µm pixel pitch CMOS APS x-ray detector named DynAMITe (Dynamic Range Adjustable for Medical Imaging Technology). The two-dimensional (2D) angle-dependent modulation transfer function (MTF), normalized noise power spectrum (NNPS), and detective quantum efficiency (DQE) were experimentally characterized and modeled using the cascaded system analysis at oblique incident angles up to 30°. The cascaded system model was extended to the 3D spatial frequency space in combination with the filtered back-projection (FBP) reconstruction method to calculate the 3D and in-plane MTF, NNPS and DQE parameters. The results demonstrate that the beam obliquity blurs the 2D MTF and DQE in the high spatial frequency range. However, this effect can be eliminated after FBP image reconstruction. In addition, impacts of the image acquisition geometry and detector parameters were evaluated using the 3D cascaded system analysis for DBT. The result shows that a wider projection angle range (e.g.  ±30°) improves the low spatial frequency (below 5 mm‑1) performance of the CMOS APS detector. In addition, to maintain a high spatial resolution for DBT, a focal spot size of smaller than 0.3 mm should be used. Theoretical analysis suggests that a pixelated scintillator in combination with the 50 µm pixel pitch CMOS APS detector could further improve the 3D image resolution. Finally, the 3D imaging performance of the CMOS APS and an indirect amorphous silicon (a-Si:H) thin-film transistor (TFT) passive pixel sensor (PPS) detector was simulated and compared.

  7. Three-dimensional cascaded system analysis of a 50 µm pixel pitch wafer-scale CMOS active pixel sensor x-ray detector for digital breast tomosynthesis.

    PubMed

    Zhao, C; Vassiljev, N; Konstantinidis, A C; Speller, R D; Kanicki, J

    2017-03-07

    High-resolution, low-noise x-ray detectors based on the complementary metal-oxide-semiconductor (CMOS) active pixel sensor (APS) technology have been developed and proposed for digital breast tomosynthesis (DBT). In this study, we evaluated the three-dimensional (3D) imaging performance of a 50 µm pixel pitch CMOS APS x-ray detector named DynAMITe (Dynamic Range Adjustable for Medical Imaging Technology). The two-dimensional (2D) angle-dependent modulation transfer function (MTF), normalized noise power spectrum (NNPS), and detective quantum efficiency (DQE) were experimentally characterized and modeled using the cascaded system analysis at oblique incident angles up to 30°. The cascaded system model was extended to the 3D spatial frequency space in combination with the filtered back-projection (FBP) reconstruction method to calculate the 3D and in-plane MTF, NNPS and DQE parameters. The results demonstrate that the beam obliquity blurs the 2D MTF and DQE in the high spatial frequency range. However, this effect can be eliminated after FBP image reconstruction. In addition, impacts of the image acquisition geometry and detector parameters were evaluated using the 3D cascaded system analysis for DBT. The result shows that a wider projection angle range (e.g.  ±30°) improves the low spatial frequency (below 5 mm(-1)) performance of the CMOS APS detector. In addition, to maintain a high spatial resolution for DBT, a focal spot size of smaller than 0.3 mm should be used. Theoretical analysis suggests that a pixelated scintillator in combination with the 50 µm pixel pitch CMOS APS detector could further improve the 3D image resolution. Finally, the 3D imaging performance of the CMOS APS and an indirect amorphous silicon (a-Si:H) thin-film transistor (TFT) passive pixel sensor (PPS) detector was simulated and compared.

  8. ALPIDE, the Monolithic Active Pixel Sensor for the ALICE ITS upgrade

    NASA Astrophysics Data System (ADS)

    Mager, M.

    2016-07-01

    A new 10 m2 inner tracking system based on seven concentric layers of Monolithic Active Pixel Sensors will be installed in the ALICE experiment during the second long shutdown of LHC in 2019-2020. The monolithic pixel sensors will be fabricated in the 180 nm CMOS Imaging Sensor process of TowerJazz. The ALPIDE design takes full advantage of a particular process feature, the deep p-well, which allows for full CMOS circuitry within the pixel matrix, while at the same time retaining the full charge collection efficiency. Together with the small feature size and the availability of six metal layers, this allowed a continuously active low-power front-end to be placed into each pixel and an in-matrix sparsification circuit to be used that sends only the addresses of hit pixels to the periphery. This approach led to a power consumption of less than 40 mWcm-2, a spatial resolution of around 5 μm, a peaking time of around 2 μs, while being radiation hard to some 1013 1 MeVneq /cm2, fulfilling or exceeding the ALICE requirements. Over the last years of R & D, several prototype circuits have been used to verify radiation hardness, and to optimize pixel geometry and in-pixel front-end circuitry. The positive results led to a submission of full-scale (3 cm×1.5 cm) sensor prototypes in 2014. They are being characterized in a comprehensive campaign that also involves several irradiation and beam tests. A summary of the results obtained and prospects towards the final sensor to instrument the ALICE Inner Tracking System are given.

  9. 1T Pixel Using Floating-Body MOSFET for CMOS Image Sensors.

    PubMed

    Lu, Guo-Neng; Tournier, Arnaud; Roy, François; Deschamps, Benoît

    2009-01-01

    We present a single-transistor pixel for CMOS image sensors (CIS). It is a floating-body MOSFET structure, which is used as photo-sensing device and source-follower transistor, and can be controlled to store and evacuate charges. Our investigation into this 1T pixel structure includes modeling to obtain analytical description of conversion gain. Model validation has been done by comparing theoretical predictions and experimental results. On the other hand, the 1T pixel structure has been implemented in different configurations, including rectangular-gate and ring-gate designs, and variations of oxidation parameters for the fabrication process. The pixel characteristics are presented and discussed.

  10. 1T Pixel Using Floating-Body MOSFET for CMOS Image Sensors

    PubMed Central

    Lu, Guo-Neng; Tournier, Arnaud; Roy, François; Deschamps, Benoît

    2009-01-01

    We present a single-transistor pixel for CMOS image sensors (CIS). It is a floating-body MOSFET structure, which is used as photo-sensing device and source-follower transistor, and can be controlled to store and evacuate charges. Our investigation into this 1T pixel structure includes modeling to obtain analytical description of conversion gain. Model validation has been done by comparing theoretical predictions and experimental results. On the other hand, the 1T pixel structure has been implemented in different configurations, including rectangular-gate and ring-gate designs, and variations of oxidation parameters for the fabrication process. The pixel characteristics are presented and discussed. PMID:22389592

  11. Evaluation of a Wobbling Method Applied to Correcting Defective Pixels of CZT Detectors in SPECT Imaging

    PubMed Central

    Xie, Zhaoheng; Li, Suying; Yang, Kun; Xu, Baixuan; Ren, Qiushi

    2016-01-01

    In this paper, we propose a wobbling method to correct bad pixels in cadmium zinc telluride (CZT) detectors, using information of related images. We build up an automated device that realizes the wobbling correction for small animal Single Photon Emission Computed Tomography (SPECT) imaging. The wobbling correction method is applied to various constellations of defective pixels. The corrected images are compared with the results of conventional interpolation method, and the correction effectiveness is evaluated quantitatively using the factor of peak signal-to-noise ratio (PSNR) and structural similarity (SSIM). In summary, the proposed wobbling method, equipped with the automatic mechanical system, provides a better image quality for correcting defective pixels, which could be used for all pixelated detectors for molecular imaging. PMID:27240368

  12. Fast Contour-Tracing Algorithm Based on a Pixel-Following Method for Image Sensors.

    PubMed

    Seo, Jonghoon; Chae, Seungho; Shim, Jinwook; Kim, Dongchul; Cheong, Cheolho; Han, Tack-Don

    2016-03-09

    Contour pixels distinguish objects from the background. Tracing and extracting contour pixels are widely used for smart/wearable image sensor devices, because these are simple and useful for detecting objects. In this paper, we present a novel contour-tracing algorithm for fast and accurate contour following. The proposed algorithm classifies the type of contour pixel, based on its local pattern. Then, it traces the next contour using the previous pixel's type. Therefore, it can classify the type of contour pixels as a straight line, inner corner, outer corner and inner-outer corner, and it can extract pixels of a specific contour type. Moreover, it can trace contour pixels rapidly because it can determine the local minimal path using the contour case. In addition, the proposed algorithm is capable of the compressing data of contour pixels using the representative points and inner-outer corner points, and it can accurately restore the contour image from the data. To compare the performance of the proposed algorithm to that of conventional techniques, we measure their processing time and accuracy. In the experimental results, the proposed algorithm shows better performance compared to the others. Furthermore, it can provide the compressed data of contour pixels and restore them accurately, including the inner-outer corner, which cannot be restored using conventional algorithms.

  13. Exploring the Hidden Structure of Astronomical Images: A "Pixelated" View of Solar System and Deep Space Features!

    ERIC Educational Resources Information Center

    Ward, R. Bruce; Sienkiewicz, Frank; Sadler, Philip; Antonucci, Paul; Miller, Jaimie

    2013-01-01

    We describe activities created to help student participants in Project ITEAMS (Innovative Technology-Enabled Astronomy for Middle Schools) develop a deeper understanding of picture elements (pixels), image creation, and analysis of the recorded data. ITEAMS is an out-of-school time (OST) program funded by the National Science Foundation (NSF) with…

  14. Pixel timing correction in time-lapsed calcium imaging using point scanning microscopy.

    PubMed

    Boiroux, Dimitri; Oke, Yoshihiko; Miwakeichi, Fumikazu; Oku, Yoshitaka

    2014-11-30

    In point scanning imaging, data are acquired by sequentially scanning each pixel of a predetermined area. This way of scanning leads to time delays between pixels, especially for lower scanning speed or large scanned areas. Therefore, experiments are often performed at lower framerates in order to ensure a sufficient signal-to-noise ratio, even though framerates above 30 frames per second are technically feasible. For these framerates, we suggest that it becomes crucial to correct the time delay between image pixels prior to analyses. In this paper, we apply temporal interpolation (or pixel timing correction) for calcium imaging in two-photon microscopy as an example of fluorescence imaging. We present and compare three interpolation methods (linear, Lanczos and cubic B-spline). We test these methods on a simulated network of coupled bursting neurons at different framerates. In this network, we introduce a time delay to simulate a scanning by point scanning microscopy. We also assess these methods on actual microscopic calcium imaging movies recorded at usual framerates. Our numerical results suggest that point scanning microscopy imaging introduces statistically significant time delays between image pixels at low frequency. However, we demonstrate that pixel timing correction compensates for these time delays, regardless of the used interpolation method.

  15. A hyperspectral image optimizing method based on sub-pixel MTF analysis

    NASA Astrophysics Data System (ADS)

    Wang, Yun; Li, Kai; Wang, Jinqiang; Zhu, Yajie

    2015-04-01

    Hyperspectral imaging is used to collect tens or hundreds of images continuously divided across electromagnetic spectrum so that the details under different wavelengths could be represented. A popular hyperspectral imaging methods uses a tunable optical band-pass filter settled in front of the focal plane to acquire images of different wavelengths. In order to alleviate the influence of chromatic aberration in some segments in a hyperspectral series, in this paper, a hyperspectral optimizing method uses sub-pixel MTF to evaluate image blurring quality was provided. This method acquired the edge feature in the target window by means of the line spread function (LSF) to calculate the reliable position of the edge feature, then the evaluation grid in each line was interpolated by the real pixel value based on its relative position to the optimal edge and the sub-pixel MTF was used to analyze the image in frequency domain, by which MTF calculation dimension was increased. The sub-pixel MTF evaluation was reliable, since no image rotation and pixel value estimation was needed, and no artificial information was introduced. With theoretical analysis, the method proposed in this paper is reliable and efficient when evaluation the common images with edges of small tilt angle in real scene. It also provided a direction for the following hyperspectral image blurring evaluation and the real-time focal plane adjustment in real time in related imaging system.

  16. Redundant Discrete Wavelet Transform Based Super-Resolution Using Sub-Pixel Image Registration

    DTIC Science & Technology

    2003-03-01

    AFIT/GE/ENG/03-18 REDUNDANT DISCRETE WAVELET TRANSFORM BASED SUPER-RESOLUTION USING SUB-PIXEL IMAGE REGISTRATION THESIS Daniel L. Ward Second...position of the United States Air Force, Department of Defense, or the United States Government. AFIT/GE/ENG/03-18 REDUNDANT DISCRETE WAVELET TRANSFORM BASED...O3-18 REDUNDANT DISCRETE WAVELET TRANSFORM BASED SUPER-RESOLUTION USING SUB-PIXEL IMAGE REGISTRATION THESIS Daniel Lee Ward, B.S.E.E. Second

  17. The HEXITEC hard x-ray pixelated CdTe imager for fast solar observations

    NASA Astrophysics Data System (ADS)

    Baumgartner, Wayne H.; Christe, Steven D.; Ryan, Daniel F.; Inglis, Andrew R.; Shih, Albert Y.; Gregory, Kyle; Wilson, Matt; Seller, Paul; Gaskin, Jessica; Wilson-Hodge, Colleen

    2016-08-01

    There is an increasing demand in solar and astrophysics for high resolution X-ray spectroscopic imaging. Such observations would present ground breaking opportunities to study the poorly understood high energy processes in our solar system and beyond, such as solar flares, X-ray binaries, and active galactic nuclei. However, such observations require a new breed of solid state detectors sensitive to high energy X-rays with fine independent pixels to sub-sample the point spread function (PSF) of the X-ray optics. For solar observations in particular, they must also be capable of handling very high count rates as photon fluxes from solar flares often cause pile up and saturation in present generation detectors. The Rutherford Appleton Laboratory (RAL) has recently developed a new cadmium telluride (CdTe) detector system, called HEXITEC (High Energy X-ray Imaging Technology). It is an 8080 array of 250 μm independent pixels sensitive in the 2-200 keV band and capable of a high full frame read out rate of 10 kHz. HEXITEC provides the smallest independently read out CdTe pixels currently available, and are well matched to the few arcsecond PSF produced by current and next generation hard X-ray focusing optics. NASA's Goddard and Marshall Space Flight Centers are collaborating with RAL to develop these detectors for use on future space borne hard X-ray focusing telescopes. We show the latest results on HEXITEC's imaging capability, energy resolution, high read out rate, and reveal it to be ideal for such future instruments.

  18. Coloured computational imaging with single-pixel detectors based on a 2D discrete cosine transform

    NASA Astrophysics Data System (ADS)

    Liu, Bao-Lei; Yang, Zhao-Hua; Liu, Xia; Wu, Ling-An

    2017-02-01

    We propose and demonstrate a computational imaging technique that uses structured illumination based on a two-dimensional discrete cosine transform to perform imaging with a single-pixel detector. A scene is illuminated by a projector with two sets of orthogonal patterns, then by applying an inverse cosine transform to the spectra obtained from the single-pixel detector a full-color image is retrieved. This technique can retrieve an image from sub-Nyquist measurements, and the background noise is easily canceled to give excellent image quality. Moreover, the experimental setup is very simple.

  19. A CMOS Active Pixel Sensor for Charged Particle Detection

    SciTech Connect

    Matis, Howard S.; Bieser, Fred; Kleinfelder, Stuart; Rai, Gulshan; Retiere, Fabrice; Ritter, Hans George; Singh, Kunal; Wurzel, Samuel E.; Wieman, Howard; Yamamoto, Eugene

    2002-12-02

    Active Pixel Sensor (APS) technology has shown promise for next-generation vertex detectors. This paper discusses the design and testing of two generations of APS chips. Both are arrays of 128 by 128 pixels, each 20 by 20 {micro}m. Each array is divided into sub-arrays in which different sensor structures (4 in the first version and 16 in the second) and/or readout circuits are employed. Measurements of several of these structures under Fe{sup 55} exposure are reported. The sensors have also been irradiated by 55 MeV protons to test for radiation damage. The radiation increased the noise and reduced the signal. The noise can be explained by shot noise from the increased leakage current and the reduction in signal is due to charge being trapped in the epi layer. Nevertheless, the radiation effect is small for the expected exposures at RHIC and RHIC II. Finally, we describe our concept for mechanically supporting a thin silicon wafer in an actual detector.

  20. Monolithic Active Pixel Matrix with Binary Counters (MAMBO) ASIC

    SciTech Connect

    Khalid, Farah F.; Deptuch, Grzegorz; Shenai, Alpana; Yarema, Raymond J.; /Fermilab

    2010-11-01

    Monolithic Active Matrix with Binary Counters (MAMBO) is a counting ASIC designed for detecting and measuring low energy X-rays from 6-12 keV. Each pixel contains analogue functionality implemented with a charge preamplifier, CR-RC{sup 2} shaper and a baseline restorer. It also contains a window comparator which can be trimmed by 4 bit DACs to remove systematic offsets. The hits are registered by a 12 bit ripple counter which is reconfigured as a shift register to serially output the data from the entire ASIC. Each pixel can be tested individually. Two diverse approaches have been used to prevent coupling between the detector and electronics in MAMBO III and MAMBO IV. MAMBO III is a 3D ASIC, the bottom ASIC consists of diodes which are connected to the top ASIC using {mu}-bump bonds. The detector is decoupled from the electronics by physically separating them on two tiers and using several metal layers as a shield. MAMBO IV is a monolithic structure which uses a nested well approach to isolate the detector from the electronics. The ASICs are being fabricated using the SOI 0.2 {micro}m OKI process, MAMBO III is 3D bonded at T-Micro and MAMBO IV nested well structure was developed in collaboration between OKI and Fermilab.

  1. Monolithic active pixel matrix with binary counters (MAMBO III) ASIC

    SciTech Connect

    Khalid, Farah; Deptuch, Grzegorz; Shenai, Alpana; Yarema, Raymond; /Fermilab

    2010-01-01

    Monolithic Active Matrix with Binary Counters (MAMBO) is a counting ASIC designed for detecting and measuring low energy X-rays from 6-12keV. Each pixel contains analogue functionality implemented with a charge preamplifier, CR-RC{sup 2} shaper and a baseline restorer. It also contains a window comparator which can be trimmed by 4 bit DACs to remove systematic offsets. The hits are registered by a 12 bit ripple counter which is reconfigured as a shift register to serially output the data from the entire ASIC. Each pixel can be tested individually. Two diverse approaches have been used to prevent coupling between the detector and electronics in MAMBO III and MAMBO IV. MAMBO III is a 3D ASIC, the bottom ASIC consists of diodes which are connected to the top ASIC using {mu}-bump bonds. The detector is decoupled from the electronics by physically separating them on two tiers and using several metal layers as a shield. MAMBO IV is a monolithic structure which uses a nested well approach to isolate the detector from the electronics. The ASICs are being fabricated using the SOI 0.2 {micro}m OKI process, MAMBO III is 3D bonded at T-Micro and MAMBO IV nested well structure was developed in collaboration between OKI and Fermilab.

  2. A self-adaptive image encryption scheme with half-pixel interchange permutation operation

    NASA Astrophysics Data System (ADS)

    Ye, Ruisong; Liu, Li; Liao, Minyu; Li, Yafang; Liao, Zikang

    2017-01-01

    A plain-image dependent image encryption scheme with half-pixel-level swapping permutation strategy is proposed. In the new permutation operation, a pixel-swapping operation between four higher bit-planes and four lower bit-planes is employed to replace the traditional confusion operation, which not only improves the conventional permutation efficiency within the plain-image, but also changes all the pixel gray values. The control parameters of generalized Arnold map applied for the permutation operation are related to the plain-image content and consequently can resist chosen-plaintext and known-plaintext attacks effectively. To enhance the security of the proposed image encryption, one multimodal skew tent map is applied to generate pseudo-random gray value sequence for diffusion operation. Simulations have been carried out thoroughly to demonstrate that the proposed image encryption scheme is highly secure thanks to its large key space and efficient permutation-diffusion operations.

  3. 50 μm pixel pitch wafer-scale CMOS active pixel sensor x-ray detector for digital breast tomosynthesis.

    PubMed

    Zhao, C; Konstantinidis, A C; Zheng, Y; Anaxagoras, T; Speller, R D; Kanicki, J

    2015-12-07

    Wafer-scale CMOS active pixel sensors (APSs) have been developed recently for x-ray imaging applications. The small pixel pitch and low noise are very promising properties for medical imaging applications such as digital breast tomosynthesis (DBT). In this work, we evaluated experimentally and through modeling the imaging properties of a 50 μm pixel pitch CMOS APS x-ray detector named DynAMITe (Dynamic Range Adjustable for Medical Imaging Technology). A modified cascaded system model was developed for CMOS APS x-ray detectors by taking into account the device nonlinear signal and noise properties. The imaging properties such as modulation transfer function (MTF), noise power spectrum (NPS), and detective quantum efficiency (DQE) were extracted from both measurements and the nonlinear cascaded system analysis. The results show that the DynAMITe x-ray detector achieves a high spatial resolution of 10 mm(-1) and a DQE of around 0.5 at spatial frequencies  <1 mm(-1). In addition, the modeling results were used to calculate the image signal-to-noise ratio (SNRi) of microcalcifications at various mean glandular dose (MGD). For an average breast (5 cm thickness, 50% glandular fraction), 165 μm microcalcifications can be distinguished at a MGD of 27% lower than the clinical value (~1.3 mGy). To detect 100 μm microcalcifications, further optimizations of the CMOS APS x-ray detector, image aquisition geometry and image reconstruction techniques should be considered.

  4. Compressive spectral polarization imaging by a pixelized polarizer and colored patterned detector.

    PubMed

    Fu, Chen; Arguello, Henry; Sadler, Brian M; Arce, Gonzalo R

    2015-11-01

    A compressive spectral and polarization imager based on a pixelized polarizer and colored patterned detector is presented. The proposed imager captures several dispersed compressive projections with spectral and polarization coding. Stokes parameter images at several wavelengths are reconstructed directly from 2D projections. Employing a pixelized polarizer and colored patterned detector enables compressive sensing over spatial, spectral, and polarization domains, reducing the total number of measurements. Compressive sensing codes are specially designed to enhance the peak signal-to-noise ratio in the reconstructed images. Experiments validate the architecture and reconstruction algorithms.

  5. Photon Counting Imaging with an Electron-Bombarded Pixel Image Sensor

    PubMed Central

    Hirvonen, Liisa M.; Suhling, Klaus

    2016-01-01

    Electron-bombarded pixel image sensors, where a single photoelectron is accelerated directly into a CCD or CMOS sensor, allow wide-field imaging at extremely low light levels as they are sensitive enough to detect single photons. This technology allows the detection of up to hundreds or thousands of photon events per frame, depending on the sensor size, and photon event centroiding can be employed to recover resolution lost in the detection process. Unlike photon events from electron-multiplying sensors, the photon events from electron-bombarded sensors have a narrow, acceleration-voltage-dependent pulse height distribution. Thus a gain voltage sweep during exposure in an electron-bombarded sensor could allow photon arrival time determination from the pulse height with sub-frame exposure time resolution. We give a brief overview of our work with electron-bombarded pixel image sensor technology and recent developments in this field for single photon counting imaging, and examples of some applications. PMID:27136556

  6. Monolithic active pixel radiation detector with shielding techniques

    DOEpatents

    Deptuch, Grzegorz W.

    2016-09-06

    A monolithic active pixel radiation detector including a method of fabricating thereof. The disclosed radiation detector can include a substrate comprising a silicon layer upon which electronics are configured. A plurality of channels can be formed on the silicon layer, wherein the plurality of channels are connected to sources of signals located in a bulk part of the substrate, and wherein the signals flow through electrically conducting vias established in an isolation oxide on the substrate. One or more nested wells can be configured from the substrate, wherein the nested wells assist in collecting charge carriers released in interaction with radiation and wherein the nested wells further separate the electronics from the sensing portion of the detector substrate. The detector can also be configured according to a thick SOA method of fabrication.

  7. Constructing Virtual Forest Scenes for Assessment of Sub-pixel Vegetation Structure From Imaging Spectroscopy

    NASA Astrophysics Data System (ADS)

    Gerace, A. D.; Yao, W.; van Aardt, J. A.; Romanczyk, P.; Kelbe, D.; van Leeuwen, M.; Kampe, T. U.

    2015-12-01

    Assessment of vegetation structure via remote sensing modalities has a long history for a range of sensor platforms. Imaging spectroscopy, while often used for biochemical measurements, also applies to structural assessment in that the Hyperspectral Infrared Imager (HyspIRI), for instance, will provide an opportunity to monitor the global ecosystem. Establishing the linkage between HyspIRI data and sub-pixel vegetation structural variation therefore is of keen interest to the remote sensing and ecology communities. NASA's AVIRIS-C was used to collect airborne data during the 2013-2015 time frame, while ground truth data were limited to 2013 due to time-consuming and labor-intensive nature of field data collection. We augmented the available field data with a first-principles, physics-based simulation approach to refine our field efforts and to maintain larger control over within-pixel variation and associated assessments. Three virtual scenes were constructed for the study, corresponding to the actual vegetation structure of the NEON's Pacific Southwest site (Fresno, CA). They presented three typical forest types: oak savanna, dense coniferous forest, and conifer manzanita mixed forest. Airborne spectrometer and a field leaf area index sensor were simulated over these scenes using the Digital Imaging and Remote Sensing Image Generation (DIRSIG) Model, a synthetic image generation model. After verifying the geometrical parameters and physical model with those replicative senses, more scenes could be constructed by changing one or more vegetation structural parameters, such as forest density, tree species, size, location, and within-pixel distribution. We constructed regression models of leaf area index (LAI, R2=0.92) and forest density(R2=0.97) with narrow-band vegetation indices through simulation. Those models can be used to improve the HyspIRI's suitability for consistent global vegetation structural assessments. The virtual scene and model can also be used in

  8. Research on remote sensing image pixel attribute data acquisition method in AutoCAD

    NASA Astrophysics Data System (ADS)

    Liu, Xiaoyang; Sun, Guangtong; Liu, Jun; Liu, Hui

    2013-07-01

    The remote sensing image has been widely used in AutoCAD, but AutoCAD lack of the function of remote sensing image processing. In the paper, ObjectARX was used for the secondary development tool, combined with the Image Engine SDK to realize remote sensing image pixel attribute data acquisition in AutoCAD, which provides critical technical support for AutoCAD environment remote sensing image processing algorithms.

  9. 1024 pixels single photon imaging array for 3D ranging

    NASA Astrophysics Data System (ADS)

    Bellisai, S.; Guerrieri, F.; Tisa, S.; Zappa, F.; Tosi, A.; Giudice, A.

    2011-01-01

    Three dimensions (3D) acquisition systems are driving applications in many research field. Nowadays 3D acquiring systems are used in a lot of applications, such as cinema industry or in automotive (for active security systems). Depending on the application, systems present different features, for example color sensitivity, bi-dimensional image resolution, distance measurement accuracy and acquisition frame rate. The system we developed acquires 3D movie using indirect Time of Flight (iTOF), starting from phase delay measurement of a sinusoidally modulated light. The system acquires live movie with a frame rate up to 50frame/s in a range distance between 10 cm up to 7.5 m.

  10. Automatic Extraction of Closed Pixel Clusters for Target Cueing in Hyperspectral Images

    SciTech Connect

    Paglieroni, D W; Perkins, D E

    2001-06-05

    Traditional algorithms for automatic target cueing (ATC) in hyperspectral images, such as the RX algorithm, treat anomaly detection as a simple hypothesis testing problem. Each decision threshold gives rise to a different set of anomalous pixels. The clustered Rx algorithm generates target cues by grouping anomalous pixels into spatial clusters, and retaining only those clusters that satisfy target specific spatial constraints. It produces one set of target cues for each of several decision thresholds, and conservatively requires {Omicron}(K{sup 2}) operations per pixel, where K is the number of spectral bands (which varies from hundreds to thousands in hyperspectral images). A novel ATC algorithm, known as ''Pixel Cluster Cueing'' (PCC), is discussed. PCC groups pixels into clusters based on spectral similarity and spatial proximity, and then selects only those clusters that satisfy target-specific spatial constraints as target cues. PCC requires only {Omicron}(K) operations per pixel, and it produces only one set of target cues because it is not an anomaly detection algorithm, i.e., it does not use a decision threshold to classify individual pixels as anomalies. PCC is compared both computationally and statistically to the RX algorithm.

  11. Restoration of hot pixels in digital imagers using lossless approximation techniques

    NASA Astrophysics Data System (ADS)

    Hadar, O.; Shleifer, A.; Cohen, E.; Dotan, Y.

    2015-09-01

    During the last twenty years, digital imagers have spread into industrial and everyday devices, such as satellites, security cameras, cell phones, laptops and more. "Hot pixels" are the main defects in remote digital cameras. In this paper we prove an improvement of existing restoration methods that use (solely or as an auxiliary tool) some average of the surrounding single pixel, such as the method of the Chapman-Koren study 1,2. The proposed method uses the CALIC algorithm and adapts it to a full use of the surrounding pixels.

  12. Sub-pixel resolving optofluidic microscope for on-chip cell imaging.

    PubMed

    Zheng, Guoan; Lee, Seung Ah; Yang, Samuel; Yang, Changhuei

    2010-11-21

    We report the implementation of a fully on-chip, lensless, sub-pixel resolving optofluidic microscope (SROFM). The device utilizes microfluidic flow to deliver specimens directly across a complementary metal oxide semiconductor (CMOS) sensor to generate a sequence of low-resolution (LR) projection images, where resolution is limited by the sensor's pixel size. This image sequence is then processed with a pixel super-resolution algorithm to reconstruct a single high resolution (HR) image, where features beyond the Nyquist rate of the LR images are resolved. We demonstrate the device's capabilities by imaging microspheres, protist Euglena gracilis, and Entamoeba invadens cysts with sub-cellular resolution and establish that our prototype has a resolution limit of 0.75 microns. Furthermore, we also apply the same pixel super-resolution algorithm to reconstruct HR videos in which the dynamic interaction between the fluid and the sample, including the in-plane and out-of-plane rotation of the sample within the flow, can be monitored in high resolution. We believe that the powerful combination of both the pixel super-resolution and optofluidic microscopy techniques within our SROFM is a significant step forwards toward a simple, cost-effective, high throughput and highly compact imaging solution for biomedical and bioscience needs.

  13. Imaging and spectroscopic performance studies of pixellated CdTe Timepix detector

    NASA Astrophysics Data System (ADS)

    Maneuski, D.; Astromskas, V.; Fröjdh, E.; Fröjdh, C.; Gimenez, E. N.; Marchal, J.; O'Shea, V.; Stewart, G.; Tartoni, N.; Wilhelm, H.; Wraight, K.; Zain, R. M.

    2012-01-01

    In this work the results on imaging and spectroscopic performances of 14 × 14 × 1 mm CdTe detectors with 55 × 55 μm and 110 × 110 μm pixel pitch bump-bonded to a Timepix chip are presented. The performance of the 110 × 110 μm pixel detector was evaluated at the extreme conditions beam line I15 of the Diamond Light Source. The energy of X-rays was set between 25 and 77 keV. The beam was collimated through the edge slits to 20 μm FWHM incident in the middle of the pixel. The detector was operated in the time-over-threshold mode, allowing direct energy measurement. Energy in the neighbouring pixels was summed for spectra reconstruction. Energy resolution at 77 keV was found to be ΔE/E = 3.9%. Comparative imaging and energy resolution studies were carried out between two pixel size detectors with a fluorescence target X-ray tube and radioactive sources. The 110 × 110 μm pixel detector exhibited systematically better energy resolution in comparison to 55 × 55 μm. An imaging performance of 55 × 55 μm pixellated CdTe detector was assessed using the Modulation Transfer Function (MTF) technique and compared to the larger pixel. A considerable degradation in MTF was observed for bias voltages below -300 V. Significant room for improvement of the detector performance was identified both for imaging and spectroscopy and is discussed.

  14. Assessing the impact of sub-pixel vegetation structure on imaging spectroscopy via simulation

    NASA Astrophysics Data System (ADS)

    Yao, Wei; van Leeuwen, Martin; Romanczyk, Paul; Kelbe, David; van Aardt, Jan

    2015-05-01

    Consistent and scalable estimation of vegetation structural parameters from imaging spectroscopy is essential to remote sensing for ecosystem studies, with applications to a wide range of biophysical assessments. To support global vegetation assessment, NASA has proposed the Hyperspectral Infrared Imager (HyspIRI) imaging spectrometer, which measures the randiance 380-2500nm in 10nm contiguous bands with 60m ground sample distance (GSD). However, because of the large pixel size on the ground, there is uncertainty as to the effects of vegetation structure on observed radiance. This research evaluates linkages between vegetation structure and imaging spectroscopy. Specifically, we assess the impact of within-pixel vegetation density and position on large-footprint spectral radiances. To achieve this objective, three virtual forest scenes were constructed, which correspond to the actual veg- etation structure of the National Ecological Observatory Network (NEON) Pacific Southwest domain (PSW; D17; Fresno, CA). These were used to simulate anticipated HyspIRI data (60m GSD) using the Digital Imaging and Remote Sensing Image Generation (DIRSIG) model, a first-principles synthetic image generation model de- veloped by the Rochester Institute of Technology. Airborne Visible / Infrared Imaging Spectrometer (AVIRIS) and NEON's high-resolution imaging spectrometer (NIS) data were used to verify the geometric parameters and physical models. Multiple simulated HyspIRI data sets were generated by varying within-pixel structural variables, such as forest density, position, and distribution of trees, in order to assess the impact of sub-pixel structural variation on observed HyspIRI data. Results indicate that HyspIRI is sensitive to sub-pixel vegetation density variation in the visible to short- wavelength infrared spectrum due to vegetation structural changes, and associated pigment and water content variation. This has implications for improving the system's suitability for

  15. Improvement of sub-pixel global motion estimation in UAV image stabilization

    NASA Astrophysics Data System (ADS)

    Li, Yingjuan; Ji, Ming; He, Junfeng; Zhen, Kang; Yang, Yizhou; Chen, Ying

    2016-01-01

    Global motion estimation within frames is very important in the UAV(unmanned aerial vehicle) image stabilization system. A fast algorithm based on phase correlation and image down-sampling in sub-pixel was proposed. First, down-sampling of the two frames to quantitatively reduce calculate data. Then, take the method based of phase correlation to realize the global motion estimation in integer-pixel. When it calculated out, chooses the overlapped area of the two frames and interpolated them with zero, then adopts the method based on phase correlation to achieve the global motion estimation in sub-pixel. At last, weighted calculate the result in integer-pixel and the result in sub-pixel, the global motion displacement in sub-pixel of the two images will be calculated out. Experimental results show that, using the proposed algorithm can not only achieve good robustness to the influence of noise, illumination and partially sheltered but also improve the accuracy of motion estimation and efficiency of computing significantly.

  16. Effect of Pansharpened Image on Some of Pixel Based and Object Based Classification Accuracy

    NASA Astrophysics Data System (ADS)

    Karakus, P.; Karabork, H.

    2016-06-01

    Classification is the most important method to determine type of crop contained in a region for agricultural planning. There are two types of the classification. First is pixel based and the other is object based classification method. While pixel based classification methods are based on the information in each pixel, object based classification method is based on objects or image objects that formed by the combination of information from a set of similar pixels. Multispectral image contains a higher degree of spectral resolution than a panchromatic image. Panchromatic image have a higher spatial resolution than a multispectral image. Pan sharpening is a process of merging high spatial resolution panchromatic and high spectral resolution multispectral imagery to create a single high resolution color image. The aim of the study was to compare the potential classification accuracy provided by pan sharpened image. In this study, SPOT 5 image was used dated April 2013. 5m panchromatic image and 10m multispectral image are pan sharpened. Four different classification methods were investigated: maximum likelihood, decision tree, support vector machine at the pixel level and object based classification methods. SPOT 5 pan sharpened image was used to classification sun flowers and corn in a study site located at Kadirli region on Osmaniye in Turkey. The effects of pan sharpened image on classification results were also examined. Accuracy assessment showed that the object based classification resulted in the better overall accuracy values than the others. The results that indicate that these classification methods can be used for identifying sun flower and corn and estimating crop areas.

  17. A GaAs pixel detectors-based digital mammographic system: Performances and imaging tests results

    NASA Astrophysics Data System (ADS)

    Annovazzi, A.; Amendolia, S. R.; Bigongiari, A.; Bisogni, M. G.; Catarsi, F.; Cesqui, F.; Cetronio, A.; Colombo, F.; Delogu, P.; Fantacci, M. E.; Gilberti, A.; Lanzieri, C.; Lavagna, S.; Novelli, M.; Passuello, G.; Paternoster, G.; Pieracci, M.; Poletti, M.; Quattrocchi, M.; Rosso, V.; Stefanini, A.; Testa, A.; Venturelli, L.

    2007-06-01

    The prototype presented in this paper is based on GaAs pixel detectors read-out by the PCC/MEDIPIX I circuit. The active area of a sensor is about 1 cm 2 therefore to cover the typical irradiation field used in mammography (18×24 cm 2), 18 GaAs detection units have been organized in two staggered rows of nine chips each and moved by a stepper motor in the orthogonal direction. The system is integrated in a mammographic equipment which comprehends the X-ray tube, the bias and data acquisition systems and the PC-based control system. The prototype has been developed in the framework of the Integrated Mammographic Imaging (IMI) project, an industrial research activity aiming to develop innovative instrumentation for morphologic and functional imaging. The project has been supported by the Italian Ministry of Education, University and Research (MIUR) and by five Italian High Tech companies, Alenia Marconi Systems (AMS), CAEN, Gilardoni, LABEN and Poli.Hi.Tech., in collaboration with the universities of Ferrara, Roma "La Sapienza", Pisa and the Istituto Nazionale di Fisica Nucleare (INFN). In this paper, we report on the electrical characterization and the first imaging test results of the digital mammographic system. To assess the imaging capability of such a detector we have built a phantom, which simulates the breast tissue with malignancies. The radiographs of the phantom, obtained by delivering an entrance dose of 4.8 mGy, have shown particulars with a measured contrast below 1%.

  18. Autonomous Sub-Pixel Satellite Track Endpoint Determination for Space Based Images

    SciTech Connect

    Simms, L M

    2011-03-07

    An algorithm for determining satellite track endpoints with sub-pixel resolution in spaced-based images is presented. The algorithm allows for significant curvature in the imaged track due to rotation of the spacecraft capturing the image. The motivation behind the subpixel endpoint determination is first presented, followed by a description of the methodology used. Results from running the algorithm on real ground-based and simulated spaced-based images are shown to highlight its effectiveness.

  19. Simulation of electronic registration of multispectral remote sensing images to 0.1 pixel accuracy

    NASA Technical Reports Server (NTRS)

    Reitsema, H. J.; Mord, A. J.; Fraser, D.; Richard, H. L.; Speaker, E. E.

    1984-01-01

    Band-to-band coregistration of multispectral remote sensing images can be achieved by electronic signal processing techniques rather than by costly and difficult mechanical alignment. This paper describes the results of a study of the end-to-end performance of electronic registration. The software simulation includes steps which model the performance of the geometric calibration process, the instrument image quality, detector performance and the effects of achieving coregistration through image resampling. The image resampling step emulates the Pipelined Resampling Processor, a real-time image resampler. The study demonstrates that the electronic alignment technique produces multispectral images which are superior to those produced by an imager whose pixel geometry is accurate to 0.1 pixel rms. The implications of this approach for future earth observation programs are discussed.

  20. The Gas Pixel Detector as a solar X-ray polarimeter and imager

    NASA Astrophysics Data System (ADS)

    Fabiani, Sergio; Bellazzini, Ronaldo; Brez, Alessandro; di Cosimo, Sergio; Lazzarotto, Francesco; Muleri, Fabio; Rubini, Alda; Soffitta, Paolo; Spandre, Gloria

    The sun is the nearest astrophysical source with an interesting emission in the X-ray band. The study of energetic events, such as solar flares, can help us to understand the behaviour of the magnetic field of our star. There are in literature numerous studies published about polarization predictions, for a wide range of solar flare models. All these models involve emission from thermal and/or nonthermal processes. Furthermore, results of flare observations in the X-ray band have never been exhaustive. We want to present a new kind of instrument with polarimetric and imaging capabilities in the X-ray band. This instrument is the Gas Pixel Detector (GPD). It has been developed by the INFN and the IASF-Roma / INAF Italian research institutes. The GPD was born to achieve X-ray polarimetric measurements as well as X-ray images for astrophysical sources. It has a good spectroscopic sensitivity thanks to an energy resolution of some per cent and it allows also to perform timing measurements. Differently from all the other kinds of today's polarimeters, it doesn't need rotation! The GPD exploits the dependence of photoelectric cross section to photon polarization direction to the aim of measuring polarization. This instrument is essentially a ionization chamber: a cell filled by gas into which radiation enters through a window of 1.5 cm x 1.5 cm. The cell has a depth of some centimeters: typically from 1 to 2 cm. Every time that a photon is absorbed by the gas, a photoelectron is emitted with more probability in the direction of the electric vector of the photon absorbed. The photoelectron propagates and produces a track of ionization that is drifted, amplified and actually collected on a fine sub-divided pixeled detector, whose pixels have a dimension of 50 µm. At the present the chip integrates more than 16.5 millions of transistors. It has an active area of 105600 pixels organized in a honeycomb matrix 300x352. It is a self triggered system able to select itself the

  1. High-speed X-ray imaging pixel array detector for synchrotron bunch isolation

    PubMed Central

    Philipp, Hugh T.; Tate, Mark W.; Purohit, Prafull; Shanks, Katherine S.; Weiss, Joel T.; Gruner, Sol M.

    2016-01-01

    A wide-dynamic-range imaging X-ray detector designed for recording successive frames at rates up to 10 MHz is described. X-ray imaging with frame rates of up to 6.5 MHz have been experimentally verified. The pixel design allows for up to 8–12 frames to be stored internally at high speed before readout, which occurs at a 1 kHz frame rate. An additional mode of operation allows the integration capacitors to be re-addressed repeatedly before readout which can enhance the signal-to-noise ratio of cyclical processes. This detector, along with modern storage ring sources which provide short (10–100 ps) and intense X-ray pulses at megahertz rates, opens new avenues for the study of rapid structural changes in materials. The detector consists of hybridized modules, each of which is comprised of a 500 µm-thick silicon X-ray sensor solder bump-bonded, pixel by pixel, to an application-specific integrated circuit. The format of each module is 128 × 128 pixels with a pixel pitch of 150 µm. In the prototype detector described here, the three-side buttable modules are tiled in a 3 × 2 array with a full format of 256 × 384 pixels. The characteristics, operation, testing and application of the detector are detailed. PMID:26917125

  2. High-speed X-ray imaging pixel array detector for synchrotron bunch isolation

    DOE PAGES

    Philipp, Hugh T.; Tate, Mark W.; Purohit, Prafull; ...

    2016-01-28

    A wide-dynamic-range imaging X-ray detector designed for recording successive frames at rates up to 10 MHz is described. X-ray imaging with frame rates of up to 6.5 MHz have been experimentally verified. The pixel design allows for up to 8–12 frames to be stored internally at high speed before readout, which occurs at a 1 kHz frame rate. An additional mode of operation allows the integration capacitors to be re-addressed repeatedly before readout which can enhance the signal-to-noise ratio of cyclical processes. This detector, along with modern storage ring sources which provide short (10–100 ps) and intense X-ray pulses atmore » megahertz rates, opens new avenues for the study of rapid structural changes in materials. The detector consists of hybridized modules, each of which is comprised of a 500 µm-thick silicon X-ray sensor solder bump-bonded, pixel by pixel, to an application-specific integrated circuit. The format of each module is 128 × 128 pixels with a pixel pitch of 150 µm. In the prototype detector described here, the three-side buttable modules are tiled in a 3 × 2 array with a full format of 256 × 384 pixels. Lastly, we detail the characteristics, operation, testing and application of the detector.« less

  3. High-speed X-ray imaging pixel array detector for synchrotron bunch isolation

    SciTech Connect

    Philipp, Hugh T.; Tate, Mark W.; Purohit, Prafull; Shanks, Katherine S.; Weiss, Joel T.; Gruner, Sol M.

    2016-01-28

    A wide-dynamic-range imaging X-ray detector designed for recording successive frames at rates up to 10 MHz is described. X-ray imaging with frame rates of up to 6.5 MHz have been experimentally verified. The pixel design allows for up to 8–12 frames to be stored internally at high speed before readout, which occurs at a 1 kHz frame rate. An additional mode of operation allows the integration capacitors to be re-addressed repeatedly before readout which can enhance the signal-to-noise ratio of cyclical processes. This detector, along with modern storage ring sources which provide short (10–100 ps) and intense X-ray pulses at megahertz rates, opens new avenues for the study of rapid structural changes in materials. The detector consists of hybridized modules, each of which is comprised of a 500 µm-thick silicon X-ray sensor solder bump-bonded, pixel by pixel, to an application-specific integrated circuit. The format of each module is 128 × 128 pixels with a pixel pitch of 150 µm. In the prototype detector described here, the three-side buttable modules are tiled in a 3 × 2 array with a full format of 256 × 384 pixels. Lastly, we detail the characteristics, operation, testing and application of the detector.

  4. Terahertz single pixel imaging with an optically controlled dynamic spatial light modulator.

    PubMed

    Shrekenhamer, David; Watts, Claire M; Padilla, Willie J

    2013-05-20

    We present a single pixel terahertz (THz) imaging technique using optical photoexcitation of semiconductors to dynamically and spatially control the electromagnetic properties of a semiconductor mask to collectively form a THz spatial light modulator (SLM). By co-propagating a THz and collimated optical laser beam through a high-resistivity silicon wafer, we are able to modify the THz transmission in real-time. By further encoding a spatial pattern on the optical beam with a digital micro-mirror device (DMD), we may write masks for THz radiation. We use masks of varying complexities ranging from 63 to 1023 pixels and are able to acquire images at speeds up to 1/2 Hz. Our results demonstrate the viability of obtaining real-time and high-fidelity THz images using an optically controlled SLM with a single pixel detector.

  5. Segmentation of bone pixels from EROI Image using clustering method for bone age assessment

    NASA Astrophysics Data System (ADS)

    Bakthula, Rajitha; Agarwal, Suneeta

    2016-03-01

    The bone age of a human can be identified using carpal and epiphysis bones ossification, which is limited to teen age. The accurate age estimation depends on best separation of bone pixels and soft tissue pixels in the ROI image. The traditional approaches like canny, sobel, clustering, region growing and watershed can be applied, but these methods requires proper pre-processing and accurate initial seed point estimation to provide accurate results. Therefore this paper proposes new approach to segment the bone from soft tissue and background pixels. First pixels are enhanced using BPE and the edges are identified by HIPI. Later a K-Means clustering is applied for segmentation. The performance of the proposed approach has been evaluated and compared with the existing methods.

  6. Heterogeneity of Particle Deposition by Pixel Analysis of 2D Gamma Scintigraphy Images

    PubMed Central

    Xie, Miao; Zeman, Kirby; Hurd, Harry; Donaldson, Scott

    2015-01-01

    Abstract Background: Heterogeneity of inhaled particle deposition in airways disease may be a sensitive indicator of physiologic changes in the lungs. Using planar gamma scintigraphy, we developed new methods to locate and quantify regions of high (hot) and low (cold) particle deposition in the lungs. Methods: Initial deposition and 24 hour retention images were obtained from healthy (n=31) adult subjects and patients with mild cystic fibrosis lung disease (CF) (n=14) following inhalation of radiolabeled particles (Tc99m-sulfur colloid, 5.4 μm MMAD) under controlled breathing conditions. The initial deposition image of the right lung was normalized to (i.e., same median pixel value), and then divided by, a transmission (Tc99m) image in the same individual to obtain a pixel-by-pixel ratio image. Hot spots were defined where pixel values in the deposition image were greater than 2X those of the transmission, and cold spots as pixels where the deposition image was less than 0.5X of the transmission. The number ratio (NR) of the hot and cold pixels to total lung pixels, and the sum ratio (SR) of total counts in hot pixels to total lung counts were compared between healthy and CF subjects. Other traditional measures of regional particle deposition, nC/P and skew of the pixel count histogram distribution, were also compared. Results: The NR of cold spots was greater in mild CF, 0.221±0.047(CF) vs. 0.186±0.038 (healthy) (p<0.005) and was significantly correlated with FEV1 %pred in the patients (R=−0.70). nC/P (central to peripheral count ratio), skew of the count histogram, and hot NR or SR were not different between the healthy and mild CF patients. Conclusions: These methods may provide more sensitive measures of airway function and localization of deposition that might be useful for assessing treatment efficacy in these patients. PMID:25393109

  7. A history of hybrid pixel detectors, from high energy physics to medical imaging

    NASA Astrophysics Data System (ADS)

    Delpierre, P.

    2014-05-01

    The aim of this paper is to describe the development of hybrid pixel detectors from the origin to the application on medical imaging. We are going to recall the need for fast 2D detectors in the high energy physics experiments and to follow the different pixel electronic circuits created to satisfy this demand. The adaptation of these circuits for X-rays will be presented as well as their industrialization. Today, a number of applications are open for these cameras, particularly for biomedical imaging applications. Some developments for clinical CT will also be shown.

  8. Development of a super B-factory monolithic active pixel detector—the Continuous Acquisition Pixel (CAP) prototypes

    NASA Astrophysics Data System (ADS)

    Varner, G.; Barbero, M.; Bozek, A.; Browder, T.; Fang, F.; Hazumi, M.; Igarashi, A.; Iwaida, S.; Kennedy, J.; Kent, N.; Olsen, S.; Palka, H.; Rosen, M.; Ruckman, L.; Stanic, S.; Trabelsi, K.; Tsuboyama, T.; Uchida, K.

    2005-04-01

    Over the last few years great progress has been made in the technological development of Monolithic Active Pixel Sensors (MAPS) such that upgrades to existing vertex detectors using this technology are now actively being considered. Future vertex detection at an upgraded KEK-B factory, already the highest luminosity collider in the world, will require a detector technology capable of withstanding the increased track densities and larger radiation exposures. Near the beam pipe the current silicon strip detectors have projected occupancies in excess of 100%. Deep sub-micron MAPS look very promising to address this problem. In the context of an upgrade to the Belle vertex detector, the major obstacles to realizing such a device have been concerns about radiation hardness and readout speed. Two prototypes implemented in the TSMC 0.35 μm process have been developed to address these issues. Denoted the Continuous Acquisition Pixel, or CAP, the two variants of this architecture are distinguished in that CAP2 includes an 8-deep sampling pipeline within each 22.5 μm 2 pixel. Preliminary test results and remaining R&D issues are presented.

  9. Compact SPAD-Based Pixel Architectures for Time-Resolved Image Sensors

    PubMed Central

    Perenzoni, Matteo; Pancheri, Lucio; Stoppa, David

    2016-01-01

    This paper reviews the state of the art of single-photon avalanche diode (SPAD) image sensors for time-resolved imaging. The focus of the paper is on pixel architectures featuring small pixel size (<25 μm) and high fill factor (>20%) as a key enabling technology for the successful implementation of high spatial resolution SPAD-based image sensors. A summary of the main CMOS SPAD implementations, their characteristics and integration challenges, is provided from the perspective of targeting large pixel arrays, where one of the key drivers is the spatial uniformity. The main analog techniques aimed at time-gated photon counting and photon timestamping suitable for compact and low-power pixels are critically discussed. The main features of these solutions are the adoption of analog counting techniques and time-to-analog conversion, in NMOS-only pixels. Reliable quantum-limited single-photon counting, self-referenced analog-to-digital conversion, time gating down to 0.75 ns and timestamping with 368 ps jitter are achieved. PMID:27223284

  10. CMOS digital pixel sensors: technology and applications

    NASA Astrophysics Data System (ADS)

    Skorka, Orit; Joseph, Dileepan

    2014-04-01

    CMOS active pixel sensor technology, which is widely used these days for digital imaging, is based on analog pixels. Transition to digital pixel sensors can boost signal-to-noise ratios and enhance image quality, but can increase pixel area to dimensions that are impractical for the high-volume market of consumer electronic devices. There are two main approaches to digital pixel design. The first uses digitization methods that largely rely on photodetector properties and so are unique to imaging. The second is based on adaptation of a classical analog-to-digital converter (ADC) for in-pixel data conversion. Imaging systems for medical, industrial, and security applications are emerging lower-volume markets that can benefit from these in-pixel ADCs. With these applications, larger pixels are typically acceptable, and imaging may be done in invisible spectral bands.

  11. Providing integrity, authenticity, and confidentiality for header and pixel data of DICOM images.

    PubMed

    Al-Haj, Ali

    2015-04-01

    Exchange of medical images over public networks is subjected to different types of security threats. This has triggered persisting demands for secured telemedicine implementations that will provide confidentiality, authenticity, and integrity for the transmitted images. The medical image exchange standard (DICOM) offers mechanisms to provide confidentiality for the header data of the image but not for the pixel data. On the other hand, it offers mechanisms to achieve authenticity and integrity for the pixel data but not for the header data. In this paper, we propose a crypto-based algorithm that provides confidentially, authenticity, and integrity for the pixel data, as well as for the header data. This is achieved by applying strong cryptographic primitives utilizing internally generated security data, such as encryption keys, hashing codes, and digital signatures. The security data are generated internally from the header and the pixel data, thus a strong bond is established between the DICOM data and the corresponding security data. The proposed algorithm has been evaluated extensively using DICOM images of different modalities. Simulation experiments show that confidentiality, authenticity, and integrity have been achieved as reflected by the results we obtained for normalized correlation, entropy, PSNR, histogram analysis, and robustness.

  12. Proof of principle study of the use of a CMOS active pixel sensor for proton radiography

    SciTech Connect

    Seco, Joao; Depauw, Nicolas

    2011-02-15

    Purpose: Proof of principle study of the use of a CMOS active pixel sensor (APS) in producing proton radiographic images using the proton beam at the Massachusetts General Hospital (MGH). Methods: A CMOS APS, previously tested for use in s-ray radiation therapy applications, was used for proton beam radiographic imaging at the MGH. Two different setups were used as a proof of principle that CMOS can be used as proton imaging device: (i) a pen with two metal screws to assess spatial resolution of the CMOS and (ii) a phantom with lung tissue, bone tissue, and water to assess tissue contrast of the CMOS. The sensor was then traversed by a double scattered monoenergetic proton beam at 117 MeV, and the energy deposition inside the detector was recorded to assess its energy response. Conventional x-ray images with similar setup at voltages of 70 kVp and proton images using commercial Gafchromic EBT 2 and Kodak X-Omat V films were also taken for comparison purposes. Results: Images were successfully acquired and compared to x-ray kVp and proton EBT2/X-Omat film images. The spatial resolution of the CMOS detector image is subjectively comparable to the EBT2 and Kodak X-Omat V film images obtained at the same object-detector distance. X-rays have apparent higher spatial resolution than the CMOS. However, further studies with different commercial films using proton beam irradiation demonstrate that the distance of the detector to the object is important to the amount of proton scatter contributing to the proton image. Proton images obtained with films at different distances from the source indicate that proton scatter significantly affects the CMOS image quality. Conclusion: Proton radiographic images were successfully acquired at MGH using a CMOS active pixel sensor detector. The CMOS demonstrated spatial resolution subjectively comparable to films at the same object-detector distance. Further work will be done in order to establish the spatial and energy resolution of the

  13. Image Mining in Remote Sensing for Coastal Wetlands Mapping: from Pixel Based to Object Based Approach

    NASA Astrophysics Data System (ADS)

    Farda, N. M.; Danoedoro, P.; Hartono; Harjoko, A.

    2016-11-01

    The availably of remote sensing image data is numerous now, and with a large amount of data it makes “knowledge gap” in extraction of selected information, especially coastal wetlands. Coastal wetlands provide ecosystem services essential to people and the environment. The aim of this research is to extract coastal wetlands information from satellite data using pixel based and object based image mining approach. Landsat MSS, Landsat 5 TM, Landsat 7 ETM+, and Landsat 8 OLI images located in Segara Anakan lagoon are selected to represent data at various multi temporal images. The input for image mining are visible and near infrared bands, PCA band, invers PCA bands, mean shift segmentation bands, bare soil index, vegetation index, wetness index, elevation from SRTM and ASTER GDEM, and GLCM (Harralick) or variability texture. There is three methods were applied to extract coastal wetlands using image mining: pixel based - Decision Tree C4.5, pixel based - Back Propagation Neural Network, and object based - Mean Shift segmentation and Decision Tree C4.5. The results show that remote sensing image mining can be used to map coastal wetlands ecosystem. Decision Tree C4.5 can be mapped with highest accuracy (0.75 overall kappa). The availability of remote sensing image mining for mapping coastal wetlands is very important to provide better understanding about their spatiotemporal coastal wetlands dynamics distribution.

  14. A pixel-based color image segmentation using support vector machine and fuzzy C-means.

    PubMed

    Wang, Xiang-Yang; Zhang, Xian-Jin; Yang, Hong-Ying; Bu, Juan

    2012-09-01

    Image segmentation is an important tool in image processing and can serve as an efficient front end to sophisticated algorithms and thereby simplify subsequent processing. In this paper, we present a pixel-based color image segmentation using Support Vector Machine (SVM) and Fuzzy C-Means (FCM). Firstly, the pixel-level color feature and texture feature of the image, which is used as input of the SVM model (classifier), are extracted via the local spatial similarity measure model and Steerable filter. Then, the SVM model (classifier) is trained by using FCM with the extracted pixel-level features. Finally, the color image is segmented with the trained SVM model (classifier). This image segmentation can not only take full advantage of the local information of the color image but also the ability of the SVM classifier. Experimental evidence shows that the proposed method has a very effective computational behavior and effectiveness, and decreases the time and increases the quality of color image segmentation in comparison with the state-of-the-art segmentation methods recently proposed in the literature.

  15. Optical confinement methods for continued scaling of CMOS image sensor pixels.

    PubMed

    Fesenmaier, Christian C; Huo, Yijie; Catrysse, Peter B

    2008-12-08

    The pixels that make up CMOS image sensors have steadily decreased in size over the last decade. This scaling has two effects: first, the amount of light incident on each pixel decreases, making optical efficiency, i.e., the collection of each photon, more important. Second, diffraction comes into play when pixel size approaches the wavelength of visible light, resulting in increased spatial optical crosstalk. To address these two effects, we investigate and compare three methods for guiding incident light from the microlens down to the photodiode. Two of these techniques rely on total internal reflection (TIR) at the boundary between dielectric media of different refractive indices, while the third uses reflection at a metal-dielectric interface to confine the light. Simulations are performed using a finite-difference time-domain (FDTD) method on a realistic 1.75-mum pixel model for on-axis as well as angled incidence. We evaluate the optical efficiency and spatial crosstalk performance of these methods compared to a reference pixel and find significant (10%) improvement for the TIR designs with properly chosen parameters and nearly full spatial crosstalk elimination using metal to confine the light. We also show that these improvements are comparable to those achieved by thinning the image sensor stack.

  16. Fast Multispectral Imaging by Spatial Pixel-Binning and Spectral Unmixing.

    PubMed

    Pan, Zhi-Wei; Shen, Hui-Liang; Li, Chunguang; Chen, Shu-Jie; Xin, John H

    2016-08-01

    Multispectral imaging system is of wide application in relevant fields for its capability in acquiring spectral information of scenes. Its limitation is that, due to the large number of spectral channels, the imaging process can be quite time-consuming when capturing high-resolution (HR) multispectral images. To resolve this limitation, this paper proposes a fast multispectral imaging framework based on the image sensor pixel-binning and spectral unmixing techniques. The framework comprises a fast imaging stage and a computational reconstruction stage. In the imaging stage, only a few spectral images are acquired in HR, while most spectral images are acquired in low resolution (LR). The LR images are captured by applying pixel binning on the image sensor, such that the exposure time can be greatly reduced. In the reconstruction stage, an optimal number of basis spectra are computed and the signal-dependent noise statistics are estimated. Then the unknown HR images are efficiently reconstructed by solving a closed-form cost function that models the spatial and spectral degradations. The effectiveness of the proposed framework is evaluated using real-scene multispectral images. Experimental results validate that, in general, the method outperforms the state of the arts in terms of reconstruction accuracy, with additional 20× or more improvement in computational efficiency.

  17. A Fast Color Image Encryption Algorithm Using 4-Pixel Feistel Structure

    PubMed Central

    Yao, Wang; Wu, Faguo; Zhang, Xiao; Zheng, Zhiming; Wang, Zhao; Wang, Wenhua; Qiu, Wangjie

    2016-01-01

    Algorithms using 4-pixel Feistel structure and chaotic systems have been shown to resolve security problems caused by large data capacity and high correlation among pixels for color image encryption. In this paper, a fast color image encryption algorithm based on the modified 4-pixel Feistel structure and multiple chaotic maps is proposed to improve the efficiency of this type of algorithm. Two methods are used. First, a simple round function based on a piecewise linear function and tent map are used to reduce computational cost during each iteration. Second, the 4-pixel Feistel structure reduces round number by changing twist direction securely to help the algorithm proceed efficiently. While a large number of simulation experiments prove its security performance, additional special analysis and a corresponding speed simulation show that these two methods increase the speed of the proposed algorithm (0.15s for a 256*256 color image) to twice that of an algorithm with a similar structure (0.37s for the same size image). Additionally, the method is also faster than other recently proposed algorithms. PMID:27824894

  18. A Fast Color Image Encryption Algorithm Using 4-Pixel Feistel Structure.

    PubMed

    Yao, Wang; Wu, Faguo; Zhang, Xiao; Zheng, Zhiming; Wang, Zhao; Wang, Wenhua; Qiu, Wangjie

    2016-01-01

    Algorithms using 4-pixel Feistel structure and chaotic systems have been shown to resolve security problems caused by large data capacity and high correlation among pixels for color image encryption. In this paper, a fast color image encryption algorithm based on the modified 4-pixel Feistel structure and multiple chaotic maps is proposed to improve the efficiency of this type of algorithm. Two methods are used. First, a simple round function based on a piecewise linear function and tent map are used to reduce computational cost during each iteration. Second, the 4-pixel Feistel structure reduces round number by changing twist direction securely to help the algorithm proceed efficiently. While a large number of simulation experiments prove its security performance, additional special analysis and a corresponding speed simulation show that these two methods increase the speed of the proposed algorithm (0.15s for a 256*256 color image) to twice that of an algorithm with a similar structure (0.37s for the same size image). Additionally, the method is also faster than other recently proposed algorithms.

  19. Integrated X-ray and charged particle active pixel CMOS sensor arrays using an epitaxial silicon sensitive region

    SciTech Connect

    Kleinfelder, Stuart; Bichsel, Hans; Bieser, Fred; Matis, Howard S.; Rai, Gulshan; Retiere, Fabrice; Weiman, Howard; Yamamoto, Eugene

    2002-07-01

    Integrated CMOS Active Pixel Sensor (APS) arrays have been fabricated and tested using X-ray and electron sources. The 128 by 128 pixel arrays, designed in a standard 0.25 micron process, use a {approx}10 micron epitaxial silicon layer as a deep detection region. The epitaxial layer has a much greater thickness than the surface features used by standard CMOS APS, leading to stronger signals and potentially better signal-to-noise ratio (SNR). On the other hand, minority carriers confined within the epitaxial region may diffuse to neighboring pixels, blur images and reduce peak signal intensity. But for low-rate, sparse-event images, centroid analysis of this diffusion may be used to increase position resolution. Careful trade-offs involving pixel size and sense-node area verses capacitance must be made to optimize overall performance. The prototype sensor arrays, therefore, include a range of different pixel designs, including different APS circuits and a range of different epitaxial layer contact structures. The fabricated arrays were tested with 1.5 GeV electrons and Fe-55 X-ray sources, yielding a measured noise of 13 electrons RMS and an SNR for single Fe-55 X-rays of greater than 38.

  20. Multi-pixel high-resolution three-dimensional imaging radar

    NASA Technical Reports Server (NTRS)

    Cooper, Ken B. (Inventor); Dengler, Robert J. (Inventor); Siegel, Peter H. (Inventor); Chattopadhyay, Goutam (Inventor); Ward, John S. (Inventor); Juan, Nuria Llombart (Inventor); Bryllert, Tomas E. (Inventor); Mehdi, Imran (Inventor); Tarsala, Jan A. (Inventor)

    2012-01-01

    A three-dimensional imaging radar operating at high frequency e.g., 670 GHz radar using low phase-noise synthesizers and a fast chirper to generate a frequency-modulated continuous-wave (FMCW) waveform, is disclosed that operates with a multiplexed beam to obtain range information simultaneously on multiple pixels of a target. A source transmit beam may be divided by a hybrid coupler into multiple transmit beams multiplexed together and directed to be reflected off a target and return as a single receive beam which is demultiplexed and processed to reveal range information of separate pixels of the target associated with each transmit beam simultaneously. The multiple transmit beams may be developed with appropriate optics to be temporally and spatially differentiated before being directed to the target. Temporal differentiation corresponds to a different intermediate frequencies separating the range information of the multiple pixels. Collinear transmit beams having differentiated polarizations may also be implemented.

  1. Denoising MR images using non-local means filter with combined patch and pixel similarity.

    PubMed

    Zhang, Xinyuan; Hou, Guirong; Ma, Jianhua; Yang, Wei; Lin, Bingquan; Xu, Yikai; Chen, Wufan; Feng, Yanqiu

    2014-01-01

    Denoising is critical for improving visual quality and reliability of associative quantitative analysis when magnetic resonance (MR) images are acquired with low signal-to-noise ratios. The classical non-local means (NLM) filter, which averages pixels weighted by the similarity of their neighborhoods, is adapted and demonstrated to effectively reduce Rician noise without affecting edge details in MR magnitude images. However, the Rician NLM (RNLM) filter usually blurs small high-contrast particle details which might be clinically relevant information. In this paper, we investigated the reason of this particle blurring problem and proposed a novel particle-preserving RNLM filter with combined patch and pixel (RNLM-CPP) similarity. The results of experiments on both synthetic and real MR data demonstrate that the proposed RNLM-CPP filter can preserve small high-contrast particle details better than the original RNLM filter while denoising MR images.

  2. Pixel Perfect

    SciTech Connect

    Perrine, Kenneth A.; Hopkins, Derek F.; Lamarche, Brian L.; Sowa, Marianne B.

    2005-09-01

    Biologists and computer engineers at Pacific Northwest National Laboratory have specified, designed, and implemented a hardware/software system for performing real-time, multispectral image processing on a confocal microscope. This solution is intended to extend the capabilities of the microscope, enabling scientists to conduct advanced experiments on cell signaling and other kinds of protein interactions. FRET (fluorescence resonance energy transfer) techniques are used to locate and monitor protein activity. In FRET, it is critical that spectral images be precisely aligned with each other despite disturbances in the physical imaging path caused by imperfections in lenses and cameras, and expansion and contraction of materials due to temperature changes. The central importance of this work is therefore automatic image registration. This runs in a framework that guarantees real-time performance (processing pairs of 1024x1024, 8-bit images at 15 frames per second) and enables the addition of other types of advanced image processing algorithms such as image feature characterization. The supporting system architecture consists of a Visual Basic front-end containing a series of on-screen interfaces for controlling various aspects of the microscope and a script engine for automation. One of the controls is an ActiveX component written in C++ for handling the control and transfer of images. This component interfaces with a pair of LVDS image capture boards and a PCI board containing a 6-million gate Xilinx Virtex-II FPGA. Several types of image processing are performed on the FPGA in a pipelined fashion, including the image registration. The FPGA offloads work that would otherwise need to be performed by the main CPU and has a guaranteed real-time throughput. Image registration is performed in the FPGA by applying a cubic warp on one image to precisely align it with the other image. Before each experiment, an automated calibration procedure is run in order to set up the

  3. Automated segmentation of geographic atrophy in fundus autofluorescence images using supervised pixel classification.

    PubMed

    Hu, Zhihong; Medioni, Gerard G; Hernandez, Matthias; Sadda, Srinivas R

    2015-01-01

    Geographic atrophy (GA) is a manifestation of the advanced or late stage of age-related macular degeneration (AMD). AMD is the leading cause of blindness in people over the age of 65 in the western world. The purpose of this study is to develop a fully automated supervised pixel classification approach for segmenting GA, including uni- and multifocal patches in fundus autofluorescene (FAF) images. The image features include region-wise intensity measures, gray-level co-occurrence matrix measures, and Gaussian filter banks. A [Formula: see text]-nearest-neighbor pixel classifier is applied to obtain a GA probability map, representing the likelihood that the image pixel belongs to GA. Sixteen randomly chosen FAF images were obtained from 16 subjects with GA. The algorithm-defined GA regions are compared with manual delineation performed by a certified image reading center grader. Eight-fold cross-validation is applied to evaluate the algorithm performance. The mean overlap ratio (OR), area correlation (Pearson's [Formula: see text]), accuracy (ACC), true positive rate (TPR), specificity (SPC), positive predictive value (PPV), and false discovery rate (FDR) between the algorithm- and manually defined GA regions are [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text], and [Formula: see text], respectively.

  4. The Mixed Pixels Estimation for LANDSAT7 Images Using the Non-linear Model and the Filtering of the Neighborhood Pixels

    NASA Astrophysics Data System (ADS)

    Ito, Seiji; Oguro, Yoshinari

    The aim of this paper is estimation of the mixture ratios for the categories in the remotely sensed images. The number of the categories is two: "Vegetation" and "Non-vegetation". The conventional method had been estimated by using the linear model, but this model is not suitable for an optical sensor. It is necessary to append the non-linear terms to consider the reflective characteristics. The pixels are affected by reflection from the neighborhood pixels, since the method for considering the neighborhood pixels should be proposed to increase the estimation accuracies. In this paper, the method using the non-linear mixed pixel model and the filtering for considering the neighborhood pixels has proposed. In order to show the effec-tiveness of the model and the filtering in the proposed method, the several simulations have done. The results of the simulations have been evaluated quantitatively by calculating the correlation coefficients between the results and the model answers which are created by using aerial photographs (higher resolution images) previously. From the results the proposed method is better than the conventional method, since the correlation coefficients of the conventional method, the proposed methods (only the non-linear model, and the non-linear model + the neighborhood filtering) are 0.157, 0.344 and 0.718 respectively.

  5. An image encryption scheme using nonlinear inter-pixel computing and swapping based permutation approach

    NASA Astrophysics Data System (ADS)

    Chen, Jun-xin; Zhu, Zhi-liang; Fu, Chong; Zhang, Li-bo; Zhang, Yushu

    2015-06-01

    Recently, intrinsic image features in bit-level (e.g., higher bit-planes carry more information than lower bit-planes) have been widely accepted for building bit-level image cryptosystems. Higher bit-planes are generally handled with enhanced encryption, whereas light attention is paid to lower ones. However, the existing achievements on bit-level image features are solely based on the analyses of standard test images, and they do not hold for some special images, such as medical images. When ciphering these images, such cryptosystems may leak the important information of lower bit-planes, and other inadaptability also exists. In this paper, we firstly give out the inapplicability of the existing bit-level achievements, and then a novel chaos-based image encryption scheme using nonlinear inter-pixel computing and swapping based permutation approach is presented. Simulations and extensive security analyses demonstrate the high level of security for practical secret applications.

  6. Reconstruction of the absorption spectrum of an object spot from the colour values of the corresponding pixel(s) in its digital image: the challenge of algal colours.

    PubMed

    Coltelli, Primo; Barsanti, Laura; Evangelista, Valter; Frassanito, Anna Maria; Gualtieri, Paolo

    2016-12-01

    A novel procedure for deriving the absorption spectrum of an object spot from the colour values of the corresponding pixel(s) in its image is presented. Any digital image acquired by a microscope can be used; typical applications are the analysis of cellular/subcellular metabolic processes under physiological conditions and in response to environmental stressors (e.g. heavy metals), and the measurement of chromophore composition, distribution and concentration in cells. In this paper, we challenged the procedure with images of algae, acquired by means of a CCD camera mounted onto a microscope. The many colours algae display result from the combinations of chromophores whose spectroscopic information is limited to organic solvents extracts that suffers from displacements, amplifications, and contraction/dilatation respect to spectra recorded inside the cell. Hence, preliminary processing is necessary, which consists of in vivo measurement of the absorption spectra of photosynthetic compartments of algal cells and determination of spectra of the single chromophores inside the cell. The final step of the procedure consists in the reconstruction of the absorption spectrum of the cell spot from the colour values of the corresponding pixel(s) in its digital image by minimization of a system of transcendental equations based on the absorption spectra of the chromophores under physiological conditions.

  7. ALPIDE: the Monolithic Active Pixel Sensor for the ALICE ITS upgrade

    NASA Astrophysics Data System (ADS)

    Šuljić, M.

    2016-11-01

    The upgrade of the ALICE vertex detector, the Inner Tracking System (ITS), is scheduled to be installed during the next long shutdown period (2019-2020) of the CERN Large Hadron Collider (LHC) . The current ITS will be replaced by seven concentric layers of Monolithic Active Pixel Sensors (MAPS) with total active surface of ~10 m2, thus making ALICE the first LHC experiment implementing MAPS detector technology on a large scale. The ALPIDE chip, based on TowerJazz 180 nm CMOS Imaging Process, is being developed for this purpose. A particular process feature, the deep p-well, is exploited so the full CMOS logic can be implemented over the active sensor area without impinging on the deposited charge collection. ALPIDE is implemented on silicon wafers with a high resistivity epitaxial layer. A single chip measures 15 mm by 30 mm and contains half a million pixels distributed in 512 rows and 1024 columns. In-pixel circuitry features amplification, shaping, discrimination and multi-event buffering. The readout is hit driven i.e. only addresses of hit pixels are sent to the periphery. The upgrade of the ITS presents two different sets of requirements for sensors of the inner and of the outer layers due to the significantly different track density, radiation level and active detector surface. The ALPIDE chip fulfils the stringent requirements in both cases. The detection efficiency is higher than 99%, fake-hit probability is orders of magnitude lower than the required 10-6 and spatial resolution within the required 5 μm. This performance is to be maintained even after a total ionising does (TID) of 2.7 Mrad and a non-ionising energy loss (NIEL) fluence of 1.7 × 1013 1 MeV neq/cm2, which is above what is expected during the detector lifetime. Readout rate of 100 kHz is provided and the power density of ALPIDE is less than 40 mW/cm2. This contribution will provide a summary of the ALPIDE features and main test results.

  8. High-Resolution Ultrasound Imaging With Unified Pixel-Based Beamforming.

    PubMed

    Nguyen, Nghia Q; Prager, Richard W

    2016-01-01

    This paper describes the development and evaluation of a new beamforming strategy based on pixel-based focusing for ultrasound linear array systems. We first implement conventional pixel-based beamforming in which the transmitted wave is assumed as spherical and diverging from the centre of the transmit subaperture. This assumed wave-shape is only valid within a limited angle on each side of the beam and this restricts the number of different subaperture positions from which data can be combined to improve image quality. By analyzing the field patterns, we propose a new unified pixel-based beamforming algorithm that better adapts to the non-spherical wave-shape of the transmit beam. This approach enables us to select the best-possible signal from each transducer waveform for data superposition. In simulations and a phantom study, we show that the unified pixel-based beamformer offers significant improvements in image quality compared to other delay-and-sum methods but at a higher computational cost. The new algorithm also demonstrates robust performance in a limited in vivo study. Overall, the results show that it is potentially of value in clinical applications.

  9. Bad Pixels, Cosmic Rays, and PSF-libraries from deep HST/WFC images

    NASA Astrophysics Data System (ADS)

    Franklin, B. E.; Duchene, N. S.; Schroeder, L. L.; Gordon, J. M.; Neuschaefer, L. W.; Windhorst, R. A.

    1992-12-01

    We present the careful removal of bad pixels and cosmic-ray (``CR'') events from HST/WFC images. The WFC bad-pixel map is known to vary with time, because the intense on-orbit CR-flux (see below) increases the dark-current of pixels that have been hit by CR's many times. This is not always properly reflected in the standard WFC dark-frames. We have thus begun a program to monitor and update ``new'' WFC bad pixels over time. Similarly, we present the construction of a library of PSF-stars from available Cycle 1 images across the WFC field-of-view in various filters. This will allow us to monitor the PSF's time- and focus-dependence, and to properly deconvolve objects seen in sub-sections of WFC images with no available nearby PSF-star (see our other HST AAS-posters this Volume). To assess the on-orbit cosmic-ray flux quantitatively, we constructed CR-clipped images from our 8---12 orbit WFC data-cube through an iterative local 2sigma -clip that uses and preserves the local S/N per pixel, and subtracted these from the straight image average. The resulting ``CR-images'' were processed with FOCAS using various detection thresholds. Differential CR ``magnitude-counts'' follow from their summed DN/unit time (as if all CR's had been misclassified as objects). The CR-``counts'' have a power-law slope gamma =~ 0.60 [N(m)~ m(gamma ) ]. At Gunn g=25 mag, the CR-``counts'' are ~ 1.0 dex higher in amplitude than the galaxy counts. They continue with a nearly ``Euclidean'' slope down to g=27.5 mag (our 1-sigma point source sensitivity), below which they turnover due to ``incompleteness'' and FOCAS splitting problems. Their formal sky-integral thus ``diverges'' into the noise, and their integral surface density approaches ~ 10(8) \\ deg(-2) down to g=28 mag, which corresponds to 1 out of every 12 pixels in the WFC data-cube, or an integrated sky-signal of at least V =~ 25.0--25.75 mag/arcsec(-2) . This work was supported by NASA/HST grants GO-2405-01-87A from STScI, which is

  10. Single-pixel three-dimensional imaging with time-based depth resolution

    NASA Astrophysics Data System (ADS)

    Sun, Ming-Jie; Edgar, Matthew P.; Gibson, Graham M.; Sun, Baoqing; Radwell, Neal; Lamb, Robert; Padgett, Miles J.

    2016-07-01

    Time-of-flight three-dimensional imaging is an important tool for applications such as object recognition and remote sensing. Conventional time-of-flight three-dimensional imaging systems frequently use a raster scanned laser to measure the range of each pixel in the scene sequentially. Here we show a modified time-of-flight three-dimensional imaging system, which can use compressed sensing techniques to reduce acquisition times, whilst distributing the optical illumination over the full field of view. Our system is based on a single-pixel camera using short-pulsed structured illumination and a high-speed photodiode, and is capable of reconstructing 128 × 128-pixel resolution three-dimensional scenes to an accuracy of ~3 mm at a range of ~5 m. Furthermore, by using a compressive sampling strategy, we demonstrate continuous real-time three-dimensional video with a frame-rate up to 12 Hz. The simplicity of the system hardware could enable low-cost three-dimensional imaging devices for precision ranging at wavelengths beyond the visible spectrum.

  11. Holographic projection of images with step-less zoom and noise suppression by pixel separation

    NASA Astrophysics Data System (ADS)

    Ducin, Izabela; Shimobaba, Tomoyoshi; Makowski, Michal; Kakarenko, Karol; Kowalczyk, Adam; Suszek, Jaroslaw; Bieda, Marcin; Kolodziejczyk, Andrzej; Sypek, Maciej

    2015-04-01

    A new method of projection of color images without color-sequential technique is proposed. It is a combination of the spatial division of the phase-only light modulator with a pixel separation noise suppression technique and an efficient propagation method called a scaled Fresnel diffraction. The unique property of a step-less and lossless zooming of the projected image is shown. The experimental demonstration of the method is presented, showing high quality, low noise images of a variable size at reasonable frame rates.

  12. Material specific X-ray imaging using an energy-dispersive pixel detector

    NASA Astrophysics Data System (ADS)

    Egan, Christopher K.; Wilson, Matthew D.; Veale, Matthew C.; Seller, Paul; Jacques, Simon D. M.; Cernik, Robert J.

    2014-04-01

    By imaging the X-ray spectral properties or ‘colours’ we have shown how material specific imaging can be performed. Using a pixelated energy-dispersive X-ray detector we record the absorbed and emitted hard X-radiation and measure the energy (colour) and intensity of the photons. Using this technology, we are not only able to obtain attenuation contrast but also to image chemical (elemental) variations inside objects, potentially opening up a very wide range of applications from materials science to medical diagnostics.

  13. Real-time imaging of methane gas leaks using a single-pixel camera.

    PubMed

    Gibson, Graham M; Sun, Baoqing; Edgar, Matthew P; Phillips, David B; Hempler, Nils; Maker, Gareth T; Malcolm, Graeme P A; Padgett, Miles J

    2017-02-20

    We demonstrate a camera which can image methane gas at video rates, using only a single-pixel detector and structured illumination. The light source is an infrared laser diode operating at 1.651μm tuned to an absorption line of methane gas. The light is structured using an addressable micromirror array to pattern the laser output with a sequence of Hadamard masks. The resulting backscattered light is recorded using a single-pixel InGaAs detector which provides a measure of the correlation between the projected patterns and the gas distribution in the scene. Knowledge of this correlation and the patterns allows an image to be reconstructed of the gas in the scene. For the application of locating gas leaks the frame rate of the camera is of primary importance, which in this case is inversely proportional to the square of the linear resolution. Here we demonstrate gas imaging at ~25 fps while using 256 mask patterns (corresponding to an image resolution of 16×16). To aid the task of locating the source of the gas emission, we overlay an upsampled and smoothed image of the low-resolution gas image onto a high-resolution color image of the scene, recorded using a standard CMOS camera. We demonstrate for an illumination of only 5mW across the field-of-view imaging of a methane gas leak of ~0.2 litres/minute from a distance of ~1 metre.

  14. Position and time resolution measurements with a microchannel plate image intensifier: A comparison of monolithic and pixelated CeBr3 scintillators

    NASA Astrophysics Data System (ADS)

    Ackermann, Ulrich; Eschbaumer, Stephan; Bergmaier, Andreas; Egger, Werner; Sperr, Peter; Greubel, Christoph; Löwe, Benjamin; Schotanus, Paul; Dollinger, Günther

    2016-07-01

    To perform Four Dimensional Age Momentum Correlation measurements in the near future, where one obtains the positron lifetime in coincidence with the three dimensional momentum of the electron annihilating with the positron, we have investigated the time and position resolution of two CeBr3 scintillators (monolithic and an array of pixels) using a Photek IPD340/Q/BI/RS microchannel plate image intensifier. The microchannel plate image intensifier has an active diameter of 40 mm and a stack of two microchannel plates in chevron configuration. The monolithic CeBr3 scintillator was cylindrically shaped with a diameter of 40 mm and a height of 5 mm. The pixelated scintillator array covered the whole active area of the microchannel plate image intensifier and the shape of each pixel was 2.5·2.5·8 mm3 with a pixel pitch of 3.3 mm. For the monolithic setup the measured mean single time resolution was 330 ps (FWHM) at a gamma energy of 511 keV. No significant dependence on the position was detected. The position resolution at the center of the monolithic scintillator was about 2.5 mm (FWHM) at a gamma energy of 662 keV. The single time resolution of the pixelated crystal setup reached 320 ps (FWHM) in the region of the center of the active area of the microchannel plate image intensifier. The position resolution was limited by the cross-section of the pixels. The gamma energy for the pixel setup measurements was 511 keV.

  15. Dependence of the appearance-based perception of criminality, suggestibility, and trustworthiness on the level of pixelation of facial images.

    PubMed

    Nurmoja, Merle; Eamets, Triin; Härma, Hanne-Loore; Bachmann, Talis

    2012-10-01

    While the dependence of face identification on the level of pixelation-transform of the images of faces has been well studied, similar research on face-based trait perception is underdeveloped. Because depiction formats used for hiding individual identity in visual media and evidential material recorded by surveillance cameras often consist of pixelized images, knowing the effects of pixelation on person perception has practical relevance. Here, the results of two experiments are presented showing the effect of facial image pixelation on the perception of criminality, trustworthiness, and suggestibility. It appears that individuals (N = 46, M age = 21.5 yr., SD = 3.1 for criminality ratings; N = 94, M age = 27.4 yr., SD = 10.1 for other ratings) have the ability to discriminate between facial cues ndicative of these perceived traits from the coarse level of image pixelation (10-12 pixels per face horizontally) and that the discriminability increases with a decrease in the coarseness of pixelation. Perceived criminality and trustworthiness appear to be better carried by the pixelized images than perceived suggestibility.

  16. A CMOS image sensor using high-speed lock-in pixels for stimulated Raman scattering

    NASA Astrophysics Data System (ADS)

    Lioe, DeXing; Mars, Kamel; Takasawa, Taishi; Yasutomi, Keita; Kagawa, Keiichiro; Hashimoto, Mamoru; Kawahito, Shoji

    2016-03-01

    A CMOS image sensor using high-speed lock-in pixels for stimulated Raman scattering (SRS) spectroscopy is presented in this paper. The effective SRS signal from the stimulated emission of SRS mechanism is very small in contrast to the offset of a probing laser source, which is in the ratio of 10-4 to 10-5. In order to extract this signal, the common offset component is removed, and the small difference component is sampled using switched-capacitor integrator with a fully differential amplifier. The sampling is performed over many integration cycles to achieve appropriate amplification. The lock-in pixels utilizes high-speed lateral electric field charge modulator (LEFM) to demodulate the SRS signal which is modulated at high-frequency of 20MHz. A prototype chip is implemented using 0.11μm CMOS image sensor technology.

  17. Development of an X-ray imaging system with SOI pixel detectors

    NASA Astrophysics Data System (ADS)

    Nishimura, Ryutaro; Arai, Yasuo; Miyoshi, Toshinobu; Hirano, Keiichi; Kishimoto, Shunji; Hashimoto, Ryo

    2016-09-01

    An X-ray imaging system employing pixel sensors in silicon-on-insulator technology is currently under development. The system consists of an SOI pixel detector (INTPIX4) and a DAQ system based on a multi-purpose readout board (SEABAS2). To correct a bottleneck in the total throughput of the DAQ of the first prototype, parallel processing of the data taking and storing processes and a FIFO buffer were implemented for the new DAQ release. Due to these upgrades, the DAQ throughput was improved from 6 Hz (41 Mbps) to 90 Hz (613 Mbps). The first X-ray imaging system with the new DAQ software release was tested using 33.3 keV and 9.5 keV mono X-rays for three-dimensional computerized tomography. The results of these tests are presented.

  18. A 58 x 62 pixel Si:Ga array camera for 5 - 14 micron astronomical imaging

    NASA Technical Reports Server (NTRS)

    Gezari, D. Y.; Folz, W. C.; Woods, L. A.; Wooldridge, J. B.

    1989-01-01

    A new infrared array camera system has been successfully applied to high background 5 - 14 micron astronomical imaging photometry observations, using a hybrid 58 x 62 pixel Si:Ga array detector. The off-axis reflective optical design incorporating a parabolic camera mirror, circular variable filter wheel, and cold aperture stop produces diffraction-limited images with negligible spatial distortion and minimum thermal background loading. The camera electronic system architecture is divided into three subsystems: (1) high-speed analog front end, including 2-channel preamp module, array address timing generator, bias power suppies, (2) two 16 bit, 3 microsec per conversion A/D converters interfaced to an arithmetic array processor, and (3) an LSI 11/73 camera control and data analysis computer. The background-limited observational noise performance of the camera at the NASA/IRTF telescope is NEFD (1 sigma) = 0.05 Jy/pixel min exp 1/2.

  19. Review of hybrid pixel detector readout ASICs for spectroscopic X-ray imaging

    NASA Astrophysics Data System (ADS)

    Ballabriga, R.; Alozy, J.; Campbell, M.; Frojdh, E.; Heijne, E. H. M.; Koenig, T.; Llopart, X.; Marchal, J.; Pennicard, D.; Poikela, T.; Tlustos, L.; Valerio, P.; Wong, W.; Zuber, M.

    2016-01-01

    Semiconductor detector readout chips with pulse processing electronics have made possible spectroscopic X-ray imaging, bringing an improvement in the overall image quality and, in the case of medical imaging, a reduction in the X-ray dose delivered to the patient. In this contribution we review the state of the art in semiconductor-detector readout ASICs for spectroscopic X-ray imaging with emphasis on hybrid pixel detector technology. We discuss how some of the key challenges of the technology (such as dealing with high fluxes, maintaining spectral fidelity, power consumption density) are addressed by the various ASICs. In order to understand the fundamental limits of the technology, the physics of the interaction of radiation with the semiconductor detector and the process of signal induction in the input electrodes of the readout circuit are described. Simulations of the process of signal induction are presented that reveal the importance of making use of the small pixel effect to minimize the impact of the slow motion of holes and hole trapping in the induced signal in high-Z sensor materials. This can contribute to preserve fidelity in the measured spectrum with relatively short values of the shaper peaking time. Simulations also show, on the other hand, the distortion in the energy spectrum due to charge sharing and fluorescence photons when the pixel pitch is decreased. However, using recent measurements from the Medipix3 ASIC, we demonstrate that the spectroscopic information contained in the incoming photon beam can be recovered by the implementation in hardware of an algorithm whereby the signal from a single photon is reconstructed and allocated to the pixel with the largest deposition.

  20. Wide-field computational color imaging using pixel super-resolved on-chip microscopy

    PubMed Central

    Greenbaum, Alon; Feizi, Alborz; Akbari, Najva; Ozcan, Aydogan

    2013-01-01

    Lens-free holographic on-chip imaging is an emerging approach that offers both wide field-of-view (FOV) and high spatial resolution in a cost-effective and compact design using source shifting based pixel super-resolution. However, color imaging has remained relatively immature for lens-free on-chip imaging, since a ‘rainbow’ like color artifact appears in reconstructed holographic images. To provide a solution for pixel super-resolved color imaging on a chip, here we introduce and compare the performances of two computational methods based on (1) YUV color space averaging, and (2) Dijkstra’s shortest path, both of which eliminate color artifacts in reconstructed images, without compromising the spatial resolution or the wide FOV of lens-free on-chip microscopes. To demonstrate the potential of this lens-free color microscope we imaged stained Papanicolaou (Pap) smears over a wide FOV of ~14 mm2 with sub-micron spatial resolution. PMID:23736466

  1. Silicon-on-insulator (SOI) active pixel sensors with the photosite implemented in the substrate

    NASA Technical Reports Server (NTRS)

    Pain, Bedabrata (Inventor); Zheng, Xinyu (Inventor)

    2002-01-01

    Active pixel sensors for a high quality imager are fabricated using a silicon-on-insulator (SOI) process by integrating the photodetectors on the SOI substrate and forming pixel readout transistors on the SOI thin-film. The technique can include forming silicon islands on a buried insulator layer disposed on a silicon substrate and selectively etching away the buried insulator layer over a region of the substrate to define a photodetector area. Dopants of a first conductivity type are implanted to form a signal node in the photodetector area and to form simultaneously drain/source regions for a first transistor in at least a first one of the silicon islands. Dopants of a second conductivity type are implanted to form drain/source regions for a second transistor in at least a second one of the silicon islands. Isolation rings around the photodetector also can be formed when dopants of the second conductivity type are implanted. Interconnections among the transistors and the photodetector are provided to allow signals sensed by the photodetector to be read out via the transistors formed on the silicon islands.

  2. Silicon-on-insulator (SOI) active pixel sensors with the photosite implemented in the substrate

    NASA Technical Reports Server (NTRS)

    Zheng, Xinyu (Inventor); Pain, Bedabrata (Inventor)

    2005-01-01

    Active pixel sensors for a high quality imager are fabricated using a silicon-on-insulator (SOI) process by integrating the photodetectors on the SOI substrate and forming pixel readout transistors on the SOI thin-film. The technique can include forming silicon islands on a buried insulator layer disposed on a silicon substrate and selectively etching away the buried insulator layer over a region of the substrate to define a photodetector area. Dopants of a first conductivity type are implanted to form a signal node in the photodetector area and to form simultaneously drain/source regions for a first transistor in at least a first one of the silicon islands. Dopants of a second conductivity type are implanted to form drain/source regions for a second transistor in at least a second one of the silicon islands. Isolation rings around the photodetector also can be formed when dopants of the second conductivity type are implanted. Interconnections among the transistors and the photodetector are provided to allow signals sensed by the photodetector to be read out via the transistors formed on the silicon islands.

  3. X-ray imaging using a 320 x 240 hybrid GaAs pixel detector

    SciTech Connect

    Irsigler, R.; Andersson, J.; Alverbro, J.

    1999-06-01

    The authors present room temperature measurements on 200 {micro}m thick GaAs pixel detectors, which were hybridized to silicon readout circuits. The whole detector array contains 320 x 240 square shaped pixel with a pitch of 38 {micro}m and is based on semi-insulating liquid-encapsulated Czochralski (LEC) GaAs material. After fabricating and dicing, the detector chips were indium bump flip chip bonded to CMOS readout circuits based on charge integration and finally evaluated. This readout chip was originally designed for the readout of flip chip bonded infrared detectors, but appears to be suitable for X-ray applications as well. A bias voltage between 50 V and 100 V was sufficient to operate the detector at room temperature. The detector array did respond to x-ray radiation by an increase in current due to production of electron hole pairs by the ionization processes. Images of various objects and slit patterns were acquired by using a standard X-ray source for dental imaging. The new X-ray hybrid detector was analyzed with respect to its imaging properties. Due to the high absorption coefficient for X-rays in GaAs and the small pixel size, the sensor shows a high modulation transfer function up to the Nyquist frequency.

  4. Pixel size adjustment in coherent diffractive imaging within the Rayleigh-Sommerfeld regime.

    PubMed

    Claus, Daniel; Rodenburg, John Marius

    2015-03-10

    The reconstruction of the smallest resolvable object detail in digital holography and coherent diffractive imaging when the detector is mounted close to the object of interest is restricted by the sensor's pixel size. Very high resolution information is intrinsically encoded in the data because the effective numerical aperture (NA) of the detector (its solid angular size as subtended at the object plane) is very high. The correct physical propagation model to use in the reconstruction process for this setup should be based on the Rayleigh-Sommerfeld diffraction integral, which is commonly implemented via a convolution operation. However, the convolution operation has the drawback that the pixel size of the propagation calculation is preserved between the object and the detector, and so the maximum resolution of the reconstruction is limited by the detector pixel size, not its effective NA. Here we show that this problem can be overcome via the introduction of a numerical spherical lens with adjustable magnification. This approach enables the reconstruction of object details smaller than the detector pixel size or of objects that extend beyond the size of the detector. It will have applications in all forms of near-field lensless microscopy.

  5. The method of x-ray image intensifies pixel matching and noise suppression based on the CCD

    NASA Astrophysics Data System (ADS)

    Yu, Shengtao; Qin, Xulei; Li, Ye

    2016-11-01

    In the proximity of X-ray imaging systems based on X-ray image intensifier, pixel matching and noise suppression are important methods to improve image quality. This paper analyzes CCD parameters' impact on imaging quality and the relations with, proposes pixel matching degree is a critical factor to restrict the performance of imaging system, and verified by experiments, the CCD refrigeration can effectively suppress the image noise, which adopts the extension of integration time method and obtains favorable signal-to-noise ratio, it also provides a simple and low cost solution for high quality X-ray real-time imaging of static objects.

  6. Assessment of illumination conditions in a single-pixel imaging configuration

    NASA Astrophysics Data System (ADS)

    Garoi, Florin; Udrea, Cristian; Damian, Cristian; Logofǎtu, Petre C.; Colţuc, Daniela

    2016-12-01

    Single-pixel imaging based on multiplexing is a promising technique, especially in applications where 2D detectors or raster scanning imaging are not readily applicable. With this method, Hadamard masks are projected on a spatial light modulator to encode an incident scene and a signal is recorded at the photodiode detector for each of these masks. Ultimately, the image is reconstructed on the computer by applying the inverse transform matrix. Thus, various algorithms were optimized and several spatial light modulators already characterized for such a task. This work analyses the imaging quality of such a single-pixel arrangement, when various illumination conditions are used. More precisely, the main comparison is made between coherent and incoherent ("white light") illumination and between two multiplexing methods, namely Hadamard and Scanning. The quality of the images is assessed by calculating their SNR, using two relations. The results show better images are obtained with "white light" illumination for the first method and coherent one for the second.

  7. Multiple-image encryption scheme with a single-pixel detector

    NASA Astrophysics Data System (ADS)

    Yuan, Sheng; Liu, Xuemei; Zhou, Xin; Li, Zhongyang

    2016-08-01

    A multiple-image encryption (MIE) scheme with a single-pixel detector has been proposed according to the principle of ghost imaging. In this scheme, each of the spatially coherent laser beams is modified by a set of phase-mask keys and illuminates on a secret image. All of the transmitted lights are recorded together by a single-pixel (bucket) detector to obtain a ciphertext, but anyone of the secret images can be decrypted from the ciphertext independently without any mutually overlapped despite some noise in them. The MIE scheme will bring convenience for data storage and transmission, especially in the case that different secret images need to be distributed to different authorized users, because the ciphertext is a real-valued function and this scheme can effectively avoid the secret images being extracted mutually. The basic principle of the MIE scheme is described theoretically and verified by computer simulations. Finally, the feasibility, robustness and encryption capacity are also tested numerically.

  8. PIXEL PUSHER

    NASA Technical Reports Server (NTRS)

    Stanfill, D. F.

    1994-01-01

    Pixel Pusher is a Macintosh application used for viewing and performing minor enhancements on imagery. It will read image files in JPL's two primary image formats- VICAR and PDS - as well as the Macintosh PICT format. VICAR (NPO-18076) handles an array of image processing capabilities which may be used for a variety of applications including biomedical image processing, cartography, earth resources, and geological exploration. Pixel Pusher can also import VICAR format color lookup tables for viewing images in pseudocolor (256 colors). This program currently supports only eight bit images but will work on monitors with any number of colors. Arbitrarily large image files may be viewed in a normal Macintosh window. Color and contrast enhancement can be performed with a graphical "stretch" editor (as in contrast stretch). In addition, VICAR images may be saved as Macintosh PICT files for exporting into other Macintosh programs, and individual pixels can be queried to determine their locations and actual data values. Pixel Pusher is written in Symantec's Think C and was developed for use on a Macintosh SE30, LC, or II series computer running System Software 6.0.3 or later and 32 bit QuickDraw. Pixel Pusher will only run on a Macintosh which supports color (whether a color monitor is being used or not). The standard distribution medium for this program is a set of three 3.5 inch Macintosh format diskettes. The program price includes documentation. Pixel Pusher was developed in 1991 and is a copyrighted work with all copyright vested in NASA. Think C is a trademark of Symantec Corporation. Macintosh is a registered trademark of Apple Computer, Inc.

  9. Study of image matching algorithm and sub-pixel fitting algorithm in target tracking

    NASA Astrophysics Data System (ADS)

    Yang, Ming-dong; Jia, Jianjun; Qiang, Jia; Wang, Jian-yu

    2015-03-01

    Image correlation matching is a tracking method that searched a region most approximate to the target template based on the correlation measure between two images. Because there is no need to segment the image, and the computation of this method is little. Image correlation matching is a basic method of target tracking. This paper mainly studies the image matching algorithm of gray scale image, which precision is at sub-pixel level. The matching algorithm used in this paper is SAD (Sum of Absolute Difference) method. This method excels in real-time systems because of its low computation complexity. The SAD method is introduced firstly and the most frequently used sub-pixel fitting algorithms are introduced at the meantime. These fitting algorithms can't be used in real-time systems because they are too complex. However, target tracking often requires high real-time performance, we put forward a fitting algorithm named paraboloidal fitting algorithm based on the consideration above, this algorithm is simple and realized easily in real-time system. The result of this algorithm is compared with that of surface fitting algorithm through image matching simulation. By comparison, the precision difference between these two algorithms is little, it's less than 0.01pixel. In order to research the influence of target rotation on precision of image matching, the experiment of camera rotation was carried on. The detector used in the camera is a CMOS detector. It is fixed to an arc pendulum table, take pictures when the camera rotated different angles. Choose a subarea in the original picture as the template, and search the best matching spot using image matching algorithm mentioned above. The result shows that the matching error is bigger when the target rotation angle is larger. It's an approximate linear relation. Finally, the influence of noise on matching precision was researched. Gaussian noise and pepper and salt noise were added in the image respectively, and the image

  10. Retrieval of the pixel component temperatures from multi-band thermal infrared image using Bayesian inversion technique

    NASA Astrophysics Data System (ADS)

    Xie, Feng; Shao, Honglan; Liu, Zhihui; Liu, Chengyu; Zhang, Changxing; Yang, Gui; Wang, Jianyu; Cai, Nengbin

    2016-04-01

    Majority of pixels, in the nature, are non-isothermal in three dimensions, especially for the pixels in meter-scale, tens- meter-scale or hundreds-meter-scale which are paid extensive attention by the researchers in geoscience field. The three-dimensional non-isothermal phenomenon even exists in some pixels in centimeter-scale. For the geosciencific researches, it is significant to determine the component temperatures of a pixel precisely. The airborne WSIS (Wide Spectrum Imaging Spectrometer) data with VNIR (visible-near infrared), SWIR (short-wave infrared) and TIR (thermal infrared) bands were used in the study. First, the components of all the pixels in the image were determined by the linear mixing method. Second, each component emissivity of each pixel was calculated based on an emissivity priori knowledge base. Last, a temperature and emissivity separation algorithm was used to inverse the mean temperature of each pixel, regarded as initial value, the Planck function was linearized to construct a multi-band equation set, and the component temperatures of every pixel were inversed by the Bayesian retrieval technique. The results suggest that the inversion precision of the pixel component temperatures is improved effectively by the Bayesian retrieval technique with the assistance of the VNIR and SWIR hyperspectral remote sensing data.

  11. Fast Imaging Detector Readout Circuits with In-Pixel ADCs for Fourier Transform Imaging Spectrometers

    NASA Technical Reports Server (NTRS)

    Rider, D.; Blavier, J-F.; Cunningham, T.; Hancock, B.; Key, R.; Pannell, Z.; Sander, S.; Seshadri, S.; Sun, C.; Wrigley, C.

    2011-01-01

    Focal plane arrays (FPAs) with high frame rates and many pixels benefit several upcoming Earth science missions including GEO-CAPE, GACM, and ACE by enabling broader spatial coverage and higher spectral resolution. FPAs for the PanFTS, a high spatial resolution Fourier transform spectrometer and a candidate instrument for the GEO-CAPE mission are the focus of the developments reported here, but this FPA technology has the potential to enable a variety of future measurements and instruments. The ESTO ACT Program funded the developed of a fast readout integrated circuit (ROIC) based on an innovative in-pixel analog-to-digital converter (ADC). The 128 X 128 pixel ROIC features 60 ?m pixels, a 14-bit ADC in each pixel and operates at a continuous frame rate of 14 kHz consuming only 1.1 W of power. The ROIC outputs digitized data completely eliminating the bulky, power consuming signal chains needed by conventional FPAs. The 128 X 128 pixel ROIC has been fabricated in CMOS and tested at the Jet Propulsion Laboratory. The current version is designed to be hybridized with PIN photodiode arrays via indium bump bonding for light detection in the visible and ultraviolet spectral regions. However, the ROIC design incorporates a small photodiode in each cell to permit detailed characterization of the ROICperformance without the need for hybridization. We will describe the essential features of the ROIC design and present results of ROIC performance measurements.

  12. Dynamic quantitative phase imaging for biological objects using a pixelated phase mask

    PubMed Central

    Creath, Katherine; Goldstein, Goldie

    2012-01-01

    This paper describes research in developing a dynamic quantitative phase imaging microscope providing instantaneous measurements of dynamic motions within and among live cells without labels or contrast agents. It utilizes a pixelated phase mask enabling simultaneous measurement of multiple interference patterns derived using the polarization properties of light to track dynamic motions and morphological changes. Optical path difference (OPD) and optical thickness (OT) data are obtained from phase images. Two different processing routines are presented to remove background surface shape to enable quantification of changes in cell position and volume over time. Data from a number of different moving biological organisms and cell cultures are presented. PMID:23162725

  13. A Hardware Design For Topographical Classification Of Pixels In An Image

    NASA Astrophysics Data System (ADS)

    Salari, Ezzatollah; Bumrungthum, Paisit

    1988-10-01

    The gray level geographical structure (GLGS) is a simple method to represent the local intensity variation of an image in symbolic description. This representation can be used in higher level image processing in subsequent steps. The advent of VLSI microelectronic technology has led to the idea of implementing the GLGS directly in hardware. A two dimensional pipelined systolic pixel classification array is proposed in this paper. In the design, each pair of processing elements processes the data in a pipelined fashion and the data in each pair of processing elements is processed in a parallel fashion to further enhance the system performance.

  14. Parallel optimization of pixel purity index algorithm for massive hyperspectral images in cloud computing environment

    NASA Astrophysics Data System (ADS)

    Chen, Yufeng; Wu, Zebin; Sun, Le; Wei, Zhihui; Li, Yonglong

    2016-04-01

    With the gradual increase in the spatial and spectral resolution of hyperspectral images, the size of image data becomes larger and larger, and the complexity of processing algorithms is growing, which poses a big challenge to efficient massive hyperspectral image processing. Cloud computing technologies distribute computing tasks to a large number of computing resources for handling large data sets without the limitation of memory and computing resource of a single machine. This paper proposes a parallel pixel purity index (PPI) algorithm for unmixing massive hyperspectral images based on a MapReduce programming model for the first time in the literature. According to the characteristics of hyperspectral images, we describe the design principle of the algorithm, illustrate the main cloud unmixing processes of PPI, and analyze the time complexity of serial and parallel algorithms. Experimental results demonstrate that the parallel implementation of the PPI algorithm on the cloud can effectively process big hyperspectral data and accelerate the algorithm.

  15. Color image encryption based on fractional Fourier transforms and pixel scrambling technique

    NASA Astrophysics Data System (ADS)

    Zhao, Jianlin; Lu, Hongqiang; Fan, Qi

    2007-01-01

    Color image encryption based on fractional Fourier transform (FRT) and pixel scrambling technique is presented in this paper. In general, color (RGB) image cannot be directly encrypted using a traditional setup for optical information processing, because which is only adapted to process two-dimensional gray image. In the proposed method, a three-dimensional RGB image is decomposed to three two-dimensional gray images (R, G and B values of the color image), and the encryption operation will be done on each two-dimensional gray image, then the encoded color image is available by composing the three two-dimensional encrypted images. The decryption process is an inverse of the encryption. The optical encrypting systems based on the presented method is proposed and simulated. Some results of computer simulation are presented to verify the flexibility and the reliability of this method. The quality of decrypted images would be debased with the difference of the fractional order. The frustrated decryption of monochromic image will affect the color of decrypted image. At the end of this paper, an all-optical and photoelectric encryption/decryption systems solution are presented, and the principle of selecting optical devices are also given.

  16. 3D reconstructions with pixel-based images are made possible by digitally clearing plant and animal tissue

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Reconstruction of 3D images from a series of 2D images has been restricted by the limited capacity to decrease the opacity of surrounding tissue. Commercial software that allows color-keying and manipulation of 2D images in true 3D space allowed us to produce 3D reconstructions from pixel based imag...

  17. A New Adaptive Diffusive Function for Magnetic Resonance Imaging Denoising Based on Pixel Similarity

    PubMed Central

    Heydari, Mostafa; Karami, Mohammad Reza

    2015-01-01

    Although there are many methods for image denoising, but partial differential equation (PDE) based denoising attracted much attention in the field of medical image processing such as magnetic resonance imaging (MRI). The main advantage of PDE-based denoising approach is laid in its ability to smooth image in a nonlinear way, which effectively removes the noise, as well as preserving edge through anisotropic diffusion controlled by the diffusive function. This function was first introduced by Perona and Malik (P-M) in their model. They proposed two functions that are most frequently used in PDE-based methods. Since these functions consider only the gradient information of a diffused pixel, they cannot remove noise in noisy images with low signal-to-noise (SNR). In this paper we propose a modified diffusive function with fractional power that is based on pixel similarity to improve P-M model for low SNR. We also will show that our proposed function will stabilize the P-M method. As experimental results show, our proposed function that is modified version of P-M function effectively improves the SNR and preserves edges more than P-M functions in low SNR. PMID:26955563

  18. Development of electron-tracking Compton imaging system with 30-μm SOI pixel sensor

    NASA Astrophysics Data System (ADS)

    Yoshihara, Y.; Shimazoe, K.; Mizumachi, Y.; Takahashi, H.; Kamada, K.; Takeda, A.; Tsuru, T.; Arai, Y.

    2017-01-01

    Compton imaging is a useful method to localize gamma sources without using mechanical collimators. In conventional Compton imaging, the incident directions of gamma rays are estimated in a cone for each event by analyzing the sequence of interactions of each gamma ray followed by Compton kinematics. Since the information of the ejection directions of the recoil electrons is lost, many artifacts in the shape of cone traces are generated, which reduces signal-to-noise ratio (SNR) and angular resolution. We have developed an advanced Compton imaging system with the capability of tracking recoil electrons by using a combination of a trigger-mode silicon-on-insulator (SOI) pixel detector and a GAGG detector. This system covers the 660-1330 keV energy range for localization of contamination nuclides such as 137Cs and 134Cs inside the Fukushima Daiichi Nuclear Power Plant in Japan. The ejection directions of recoil electrons caused by Compton scattering are detected on the micro-pixelated SOI detector, which can theoretically be used to determine the incident directions of the gamma rays in a line for each event and can reduce the appearance of artifacts. We obtained 2-D reconstructed images from the first iteration of the proposed system for 137Cs, and the SNR and angular resolution were enhanced compared with those of conventional Compton imaging systems.

  19. DETECTORS AND EXPERIMENTAL METHODS: Study of the characteristics of a scintillation array and single pixels for nuclear medicine imaging applications

    NASA Astrophysics Data System (ADS)

    Zhu, Jie; Ma, Hong-Guang; Ma, Wen-Yan; Zeng, Hui; Wang, Zhao-Min; Xu, Zi-Zong

    2009-04-01

    By using a pixelized Nal(Tl) crystal array coupled to a R2486 PSPMT, the characteristics of the array and of a single pixel, such as the light output, energy resolution, peak-to-valley ratio (P/V) and imaging performance of the detector were studied. The pixel size of the NaI(TI) scintillation pixel array is 2 mm×2 mm×5 mm. There are in total 484 pixels in a 22 × 22 matrix. In the pixel spectrum an average peak-to-valley ratio (P/V) of 16 was obtained. In the image of all the pixels, good values for the Peak-to-Valley ratios could be achieved, namely a mean of 17, a maximum of 45 and the average peak FWHM (the average value of intrinsic spatial resolution) of 2.3 mm. However, the PSPMT non-uniform response and the scintillation pixels array inhomogeneities degrade the imaging performance of the detector.

  20. Pixelation effect removal from fiber bundle probe based optical coherence tomography imaging.

    PubMed

    Han, Jae-Ho; Lee, Junghoon; Kang, Jin U

    2010-03-29

    A method of eliminating pixelization effect from en face optical coherence tomography (OCT) image when a fiber bundle is used as an OCT imaging probe is presented. We have demonstrated that applying a histogram equalization process before performing a weighted-averaged Gaussian smoothing filter to the original lower gray level intensity based image not only removes the structural artifact of the bundle but also enhances the image quality with minimum blurring of object's image features. The measured contrast-to-noise ratio (CNR) for an image of the US Air Force test target was 14.7dB (4.9dB), after (before) image processing. In addition, by performing the spatial frequency analysis based on two-dimensional discrete Fourier transform (2-D DFT), we were able to observe that the periodic intensity peaks induced by the regularly arrayed structure of the fiber bundle can be efficiently suppressed by 41.0dB for the first nearby side lobe as well as to obtain the precise physical spacing information of the fiber grid. The proposed combined method can also be used as a straight forward image processing tool for any imaging system utilizing fiber bundle as a high-resolution imager.

  1. Center of mass detection via an active pixel sensor

    NASA Technical Reports Server (NTRS)

    Yadid-Pecht, Orly (Inventor); Minch, Brad (Inventor); Pain, Bedabrara (Inventor); Fossum, Eric (Inventor)

    2006-01-01

    An imaging system for identifying the location of the center of mass (COM) in an image. In one aspect, an imaging system includes a plurality of photosensitive elements arranged in a matrix. A center of mass circuit coupled to the photosensitive elements includes a resistive network and a normalization circuit including at least one bipolar transistor. The center of mass circuit identifies a center of mass location in the matrix and includes: a row circuit, where the row circuit identifies a center of mass row value in each row of the matrix and identifies a row intensity for each row; a horizontal circuit, where the horizontal circuit identifies a center of mass horizontal value; and a vertical circuit, where the vertical circuit identifies a center of mass vertical value. The horizontal and vertical center of mass values indicate the coordinates of the center of mass location for the image.

  2. Center of mass detection via an active pixel sensor

    NASA Technical Reports Server (NTRS)

    Yadid-Pecht, Orly (Inventor); Minch, Brad (Inventor); Pain, Bedabrata (Inventor); Fossum, Eric (Inventor)

    2005-01-01

    An imaging system for identifying the location of the center of mass (COM) in an image. In one aspect, an imaging system includes a plurality of photosensitive elements arranged in a matrix. A center of mass circuit coupled to the photosensitive elements includes a resistive network and a normalization circuit including at least one bipolar transistor. The center of mass circuit identifies a center of mass location in the matrix and includes: a row circuit, where the row circuit identifies a center of mass row value in each row of the matrix and identifies a row intensity for each row; a horizontal circuit, where the horizontal circuit identifies a center of mass horizontal value; and a vertical circuit, where the vertical circuit identifies a center of mass vertical value. The horizontal and vertical center of mass values indicate the coordinates of the center of mass location for the image.

  3. Center of mass detection via an active pixel sensor

    NASA Technical Reports Server (NTRS)

    Yadid-Pecht, Orly (Inventor); Minch, Brad (Inventor); Pain, Bedabrata (Inventor); Fossum, Eric (Inventor)

    2002-01-01

    An imaging system for identifying the location of the center of mass (COM) in an image. In one aspect, an imaging system includes a plurality of photosensitive elements arranged in a matrix. A center of mass circuit coupled to the photosensitive elements includes a resistive network and a normalization circuit including at least one bipolar transistor. The center of mass circuit identifies a center of mass location in the matrix and includes: a row circuit, where the row circuit identifies a center of mass row value in each row of the matrix and identifies a row intensity for each row; a horizontal circuit, where the horizontal circuit identifies a center of mass horizontal value; and a vertical circuit, where the vertical circuit identifies a center of mass vertical value. The horizontal and vertical center of mass values indicate the coordinates of the center of mass location for the image.

  4. High resolution phoswich gamma-ray imager utilizing monolithic MPPC arrays with submillimeter pixelized crystals

    NASA Astrophysics Data System (ADS)

    Kato, T.; Kataoka, J.; Nakamori, T.; Kishimoto, A.; Yamamoto, S.; Sato, K.; Ishikawa, Y.; Yamamura, K.; Kawabata, N.; Ikeda, H.; Kamada, K.

    2013-05-01

    We report the development of a high spatial resolution tweezers-type coincidence gamma-ray camera for medical imaging. This application consists of large-area monolithic Multi-Pixel Photon Counters (MPPCs) and submillimeter pixelized scintillator matrices. The MPPC array has 4 × 4 channels with a three-side buttable, very compact package. For typical operational gain of 7.5 × 105 at + 20 °C, gain fluctuation over the entire MPPC device is only ± 5.6%, and dark count rates (as measured at the 1 p.e. level) amount to <= 400 kcps per channel. We selected Ce-doped (Lu,Y)2(SiO4)O (Ce:LYSO) and a brand-new scintillator, Ce-doped Gd3Al2Ga3O12 (Ce:GAGG) due to their high light yield and density. To improve the spatial resolution, these scintillators were fabricated into 15 × 15 matrices of 0.5 × 0.5 mm2 pixels. The Ce:LYSO and Ce:GAGG scintillator matrices were assembled into phosphor sandwich (phoswich) detectors, and then coupled to the MPPC array along with an acrylic light guide measuring 1 mm thick, and with summing operational amplifiers that compile the signals into four position-encoded analog outputs being used for signal readout. Spatial resolution of 1.1 mm was achieved with the coincidence imaging system using a 22Na point source. These results suggest that the gamma-ray imagers offer excellent potential for applications in high spatial medical imaging.

  5. Supervised pixel classification for segmenting geographic atrophy in fundus autofluorescene images

    NASA Astrophysics Data System (ADS)

    Hu, Zhihong; Medioni, Gerard G.; Hernandez, Matthias; Sadda, SriniVas R.

    2014-03-01

    Age-related macular degeneration (AMD) is the leading cause of blindness in people over the age of 65. Geographic atrophy (GA) is a manifestation of the advanced or late-stage of the AMD, which may result in severe vision loss and blindness. Techniques to rapidly and precisely detect and quantify GA lesions would appear to be of important value in advancing the understanding of the pathogenesis of GA and the management of GA progression. The purpose of this study is to develop an automated supervised pixel classification approach for segmenting GA including uni-focal and multi-focal patches in fundus autofluorescene (FAF) images. The image features include region wise intensity (mean and variance) measures, gray level co-occurrence matrix measures (angular second moment, entropy, and inverse difference moment), and Gaussian filter banks. A k-nearest-neighbor (k-NN) pixel classifier is applied to obtain a GA probability map, representing the likelihood that the image pixel belongs to GA. A voting binary iterative hole filling filter is then applied to fill in the small holes. Sixteen randomly chosen FAF images were obtained from sixteen subjects with GA. The algorithm-defined GA regions are compared with manual delineation performed by certified graders. Two-fold cross-validation is applied for the evaluation of the classification performance. The mean Dice similarity coefficients (DSC) between the algorithm- and manually-defined GA regions are 0.84 +/- 0.06 for one test and 0.83 +/- 0.07 for the other test and the area correlations between them are 0.99 (p < 0.05) and 0.94 (p < 0.05) respectively.

  6. Performance assessment of a single-pixel compressive sensing imaging system

    NASA Astrophysics Data System (ADS)

    Du Bosq, Todd W.; Preece, Bradley L.

    2016-05-01

    Conventional electro-optical and infrared (EO/IR) systems capture an image by measuring the light incident at each of the millions of pixels in a focal plane array. Compressive sensing (CS) involves capturing a smaller number of unconventional measurements from the scene, and then using a companion process known as sparse reconstruction to recover the image as if a fully populated array that satisfies the Nyquist criteria was used. Therefore, CS operates under the assumption that signal acquisition and data compression can be accomplished simultaneously. CS has the potential to acquire an image with equivalent information content to a large format array while using smaller, cheaper, and lower bandwidth components. However, the benefits of CS do not come without compromise. The CS architecture chosen must effectively balance between physical considerations (SWaP-C), reconstruction accuracy, and reconstruction speed to meet operational requirements. To properly assess the value of such systems, it is necessary to fully characterize the image quality, including artifacts and sensitivity to noise. Imagery of the two-handheld object target set at range was collected using a passive SWIR single-pixel CS camera for various ranges, mirror resolution, and number of processed measurements. Human perception experiments were performed to determine the identification performance within the trade space. The performance of the nonlinear CS camera was modeled with the Night Vision Integrated Performance Model (NV-IPM) by mapping the nonlinear degradations to an equivalent linear shift invariant model. Finally, the limitations of CS modeling techniques will be discussed.

  7. Recent progress in the development of a B-factory monolithic active pixel detector

    NASA Astrophysics Data System (ADS)

    Stanič, S.; Aihara, H.; Barbero, M.; Bozek, A.; Browder, T.; Hazumi, M.; Kennedy, J.; Kent, N.; Olsen, S.; Palka, H.; Rosen, M.; Ruckman, L.; Trabelsi, K.; Tsuboyama, T.; Uchida, K.; Varner, G.; Yang, Q.

    2006-11-01

    Due to the need for precise vertexing at future higher luminosity B-factories with the expectedly increasing track densities and radiation exposures, upgrade of present silicon strip detectors with thin, radiation resistant pixel detectors is highly desired. Considerable progress in the technological development of thin CMOS based Monolithic Active Pixel Sensors (MAPS) in the last years makes them a realistic upgrade option and the feasibility studies of their application in Belle are actively pursued. The most serious concerns are their radiation hardness and their read-out speed. To address them, several prototypes denoted as Continuous Acquisition Pixel (CAP) sensors have been developed and tested. The latest of the CAP sensor prototypes is CAP3, designed in the TSMC 0.25 μm process with a 5-deep sample pair pipeline in each pixel. A setup with several CAP3 sensors will be used to assess the performance of a full scale pixel read-out system running at realistic read-out speed. The results and plans for the next stages of R&D towards a full Pixel Vertex Detector (PVD) are presented.

  8. Development of Gated Pinned Avalanche Photodiode Pixels for High-Speed Low-Light Imaging

    PubMed Central

    Resetar, Tomislav; De Munck, Koen; Haspeslagh, Luc; Rosmeulen, Maarten; Süss, Andreas; Puers, Robert; Van Hoof, Chris

    2016-01-01

    This work explores the benefits of linear-mode avalanche photodiodes (APDs) in high-speed CMOS imaging as compared to different approaches present in literature. Analysis of APDs biased below their breakdown voltage employed in single-photon counting mode is also discussed, showing a potentially interesting alternative to existing Geiger-mode APDs. An overview of the recently presented gated pinned avalanche photodiode pixel concept is provided, as well as the first experimental results on a 8 × 16 pixel test array. Full feasibility of the proposed pixel concept is not demonstrated; however, informative data is obtained from the sensor operating under −32 V substrate bias and clearly exhibiting wavelength-dependent gain in frontside illumination. The readout of the chip designed in standard 130 nm CMOS technology shows no dependence on the high-voltage bias. Readout noise level of 15 e- rms, full well capacity of 8000e-, and the conversion gain of 75 µV/e- are extracted from the photon-transfer measurements. The gain characteristics of the avalanche junction are characterized on separate test diodes showing a multiplication factor of 1.6 for red light in frontside illumination. PMID:27537882

  9. Prototype AEGIS: A Pixel-Array Readout Circuit for Gamma-Ray Imaging

    PubMed Central

    Barber, H. Bradford; Augustine, F. L.; Furenlid, L.; Ingram, C. M.; Grim, G. P.

    2015-01-01

    Semiconductor detector arrays made of CdTe/CdZnTe are expected to be the main components of future high-performance, clinical nuclear medicine imaging systems. Such systems will require small pixel-pitch and much larger numbers of pixels than are available in current semiconductor-detector cameras. We describe the motivation for developing a new readout integrated circuit, AEGIS, for use in hybrid semiconductor detector arrays, that may help spur the development of future cameras. A basic design for AEGIS is presented together with results of an HSPICE™ simulation of the performance of its unit cell. AEGIS will have a shaper-amplifier unit cell and neighbor pixel readout. Other features include the use of a single input power line with other biases generated on-board, a control register that allows digital control of all thresholds and chip configurations and an output approach that is compatible with list-mode data acquisition. An 8×8 prototype version of AEGIS is currently under development; the full AEGIS will be a 64×64 array with 300 μm pitch. PMID:26345126

  10. Generalized approach to inverse problems in tomography: Image reconstruction for spatially variant systems using natural pixels

    SciTech Connect

    Baker, J.R.; Budinger, T.F.; Huesman, R.H.

    1992-10-01

    A major limitation in tomographic inverse problems is inadequate computation speed, which frequently impedes the application of engineering ideas and principles in medical science more than in the physical and engineering sciences. Medical problems are computationally taxing because a minimum description of the system often involves 5 dimensions (3 space, 1 energy, 1 time), with the range of each space coordinate requiring up to 512 samples. The computational tasks for this problem can be simply expressed by posing the problem as one in which the tomograph system response function is spatially invariant, and the noise is additive and Gaussian. Under these assumptions, a number of reconstruction methods have been implemented with generally satisfactory results for general medical imaging purposes. However, if the system response function of the tomograph is assumed more realistically to be spatially variant and the noise to be Poisson, the computational problem becomes much more difficult. Some of the algorithms being studied to compensate for position dependent resolution and statistical fluctuations in the data acquisition process, when expressed in canonical form, are not practical for clinical applications because the number of computations necessary exceeds the capabilities of high performance computer systems currently available. Reconstruction methods based on natural pixels, specifically orthonormal natural pixels, preserve symmetries in the data acquisition process. Fast implementations of orthonormal natural pixel algorithms can achieve orders of magnitude speedup relative to general implementations. Thus, specialized thought in algorithm development can lead to more significant increases in performance than can be achieved through hardware improvements alone.

  11. How spectroscopic x-ray imaging benefits from inter-pixel communication

    NASA Astrophysics Data System (ADS)

    Koenig, Thomas; Zuber, Marcus; Hamann, Elias; Cecilia, Angelica; Ballabriga, Rafael; Campbell, Michael; Ruat, Marie; Tlustos, Lukas; Fauler, Alex; Fiederle, Michael; Baumbach, Tilo

    2014-10-01

    Spectroscopic x-ray imaging based on pixellated semiconductor detectors can be sensitive to charge sharing and K-fluorescence, depending on the sensor material used, its thickness and the pixel pitch employed. As a consequence, spectroscopic resolution is partially lost. In this paper, we study a new detector ASIC, the Medipix3RX, that offers a novel feature called charge summing, which is established by making adjacent pixels communicate with each other. Consequently, single photon interactions resulting in multiple hits are almost completely avoided. We investigate this charge summing mode with respect to those of its imaging properties that are of interest in medical physics and benchmark them against the case without charge summing. In particular, we review its influence on spectroscopic resolution and find that the low energy bias normally present when recording energy spectra is dramatically reduced. Furthermore, we show that charge summing provides a modulation transfer function which is almost independent of the energy threshold setting, which is in contrast to approaches common so far. We demonstrate that this property is directly linked to the detective quantum efficiency, which is found to increase by a factor of three or more when the energy threshold approaches the photon energy and when using charge summing. As a consequence, the contrast-to-noise ratio is found to double at elevated threshold levels and the dynamic range increases for a given counter depth. All these effects are shown to lead to an improved ability to perform material discrimination in spectroscopic CT, using iodine and gadolinium contrast agents. Hence, when compared to conventional photon counting detectors, these benefits carry the potential of substantially reducing the imaging dose a patient is exposed to during diagnostic CT examinations.

  12. 3-D Spatial Resolution of 350 μm Pitch Pixelated CdZnTe Detectors for Imaging Applications

    PubMed Central

    Yin, Yongzhi; Chen, Ximeng; Wu, Heyu; Komarov, Sergey; Garson, Alfred; Li, Qiang; Guo, Qingzhen; Krawczynski, Henric; Meng, Ling-Jian; Tai, Yuan-Chuan

    2016-01-01

    We are currently investigating the feasibility of using highly pixelated Cadmium Zinc Telluride (CdZnTe) detectors for sub-500 μm resolution PET imaging applications. A 20 mm × 20 mm × 5 mm CdZnTe substrate was fabricated with 350 μm pitch pixels (250 μm anode pixels with 100 μm gap) and coplanar cathode. Charge sharing among the pixels of a 350 μm pitch detector was studied using collimated 122 keV and 511 keV gamma ray sources. For a 350 μm pitch CdZnTe detector, scatter plots of the charge signal of two neighboring pixels clearly show more charge sharing when the collimated beam hits the gap between adjacent pixels. Using collimated Co-57 and Ge-68 sources, we measured the count profiles and estimated the intrinsic spatial resolution of 350 μm pitch detector biased at −1000 V. Depth of interaction was analyzed based on two methods, i.e., cathode/anode ratio and electron drift time, in both 122 keV and 511 keV measurements. For single-pixel photopeak events, a linear correlation between cathode/anode ratio and electron drift time was shown, which would be useful for estimating the DOI information and preserving image resolution in CdZnTe PET imaging applications. PMID:28250476

  13. Toward Real-time quantum imaging with a single pixel camera

    SciTech Connect

    Lawrie, Benjamin J; Pooser, Raphael C

    2013-01-01

    We present a workbench for the study of real-time quantum imaging by measuring the frame-by-frame quantum noise reduction of multi-spatial-mode twin beams generated by four wave mixing in Rb vapor. Exploiting the multiple spatial modes of this squeezed light source, we utilize spatial light modulators to selectively transmit macropixels of quantum correlated modes from each of the twin beams to a high quantum efficiency balanced detector. In low-light-level imaging applications, the ability to measure the quantum correlations between individual spatial modes and macropixels of spatial modes with a single pixel camera will facilitate compressive quantum imaging with sensitivity below the photon shot noise limit.

  14. Microconcentrators to recover fill-factor in image photodetectors with pixel on-board processing circuits.

    PubMed

    Donati, Silvano; Martini, Giuseppe; Norgia, Michele

    2007-12-24

    We propose an array of non-imaging micro-concentrators as a mean to recover the loss of sensitivity due to area fill-factor. This is particularly important for those image photo detectors in which complex circuit functions are required and a substantial fraction of the pixel area is consumed, like e.g., 3D camera, SPAD arrays, fluorescence analyzers, etc., but also in CMOS sensors. So far, the low fill-factor was an unacceptable loss of sensitivity precluding from the development of such devices, whereas by using a concentrator array a recovery is possible, up to the inverse square of numerical aperture of the objective lens. By ray tracing, we calculate the concentration factors of several geometries of non-imaging concentrator, i.e., truncated cone, parabolic and compound parabolic, both reflective and refractive. The feasibility of a sizeable recovery of fill-factor (up to 50) is demonstrated.

  15. Guided compressive sensing single-pixel imaging technique based on hierarchical model

    NASA Astrophysics Data System (ADS)

    Peng, Yang; Liu, Yu; Ren, Weiya; Tan, Shuren; Zhang, Maojun

    2016-04-01

    Single-pixel imaging has emerged a decade ago as an imaging technique that exploits the theory of compressive sensing. In this research, the problem of optimizing the measurement matrix in compressive sensing framework was addressed. Thus far, random measurement matrices are widely used because they provide small coherence. However, recent reports claim that measurement matrix can be optimized, thereby improving its performance. Based on such proposition, this study proposed an alternative approach of optimizing the measurement matrix in a hierarchical model. In particular, this study constructed the hierarchical model based on an increasing resolution grade by exploiting the guided information and the adaptive step size method. An image with a demanded resolution was then obtained using the l1-norm method. Subsequently, the performance of the introduced method was verified and compared with those of existing approaches via several experiments. Results of the tests indicated that the reconstruction quality of optimizing the measurement matrix was improved when the proposed method was used.

  16. Spectral-spatial hyperspectral image classification using super-pixel-based spatial pyramid representation

    NASA Astrophysics Data System (ADS)

    Fan, Jiayuan; Tan, Hui Li; Toomik, Maria; Lu, Shijian

    2016-10-01

    Spatial pyramid matching has demonstrated its power for image recognition task by pooling features from spatially increasingly fine sub-regions. Motivated by the concept of feature pooling at multiple pyramid levels, we propose a novel spectral-spatial hyperspectral image classification approach using superpixel-based spatial pyramid representation. This technique first generates multiple superpixel maps by decreasing the superpixel number gradually along with the increased spatial regions for labelled samples. By using every superpixel map, sparse representation of pixels within every spatial region is then computed through local max pooling. Finally, features learned from training samples are aggregated and trained by a support vector machine (SVM) classifier. The proposed spectral-spatial hyperspectral image classification technique has been evaluated on two public hyperspectral datasets, including the Indian Pines image containing 16 different agricultural scene categories with a 20m resolution acquired by AVIRIS and the University of Pavia image containing 9 land-use categories with a 1.3m spatial resolution acquired by the ROSIS-03 sensor. Experimental results show significantly improved performance compared with the state-of-the-art works. The major contributions of this proposed technique include (1) a new spectral-spatial classification approach to generate feature representation for hyperspectral image, (2) a complementary yet effective feature pooling approach, i.e. the superpixel-based spatial pyramid representation that is used for the spatial correlation study, (3) evaluation on two public hyperspectral image datasets with superior image classification performance.

  17. A robust sub-pixel edge detection method of infrared image based on tremor-based retinal receptive field model

    NASA Astrophysics Data System (ADS)

    Gao, Kun; Yang, Hu; Chen, Xiaomei; Ni, Guoqiang

    2008-03-01

    Because of complex thermal objects in an infrared image, the prevalent image edge detection operators are often suitable for a certain scene and extract too wide edges sometimes. From a biological point of view, the image edge detection operators work reliably when assuming a convolution-based receptive field architecture. A DoG (Difference-of- Gaussians) model filter based on ON-center retinal ganglion cell receptive field architecture with artificial eye tremors introduced is proposed for the image contour detection. Aiming at the blurred edges of an infrared image, the subsequent orthogonal polynomial interpolation and sub-pixel level edge detection in rough edge pixel neighborhood is adopted to locate the foregoing rough edges in sub-pixel level. Numerical simulations show that this method can locate the target edge accurately and robustly.

  18. Estimation of urban surface water at subpixel level from neighborhood pixels using multispectral remote sensing image (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Xie, Huan; Luo, Xin; Xu, Xiong; Wang, Chen; Pan, Haiyan; Tong, Xiaohua; Liu, Shijie

    2016-10-01

    Water body is a fundamental element in urban ecosystems and water mapping is critical for urban and landscape planning and management. As remote sensing has increasingly been used for water mapping in rural areas, this spatially explicit approach applied in urban area is also a challenging work due to the water bodies mainly distributed in a small size and the spectral confusion widely exists between water and complex features in the urban environment. Water index is the most common method for water extraction at pixel level, and spectral mixture analysis (SMA) has been widely employed in analyzing urban environment at subpixel level recently. In this paper, we introduce an automatic subpixel water mapping method in urban areas using multispectral remote sensing data. The objectives of this research consist of: (1) developing an automatic land-water mixed pixels extraction technique by water index; (2) deriving the most representative endmembers of water and land by utilizing neighboring water pixels and adaptive iterative optimal neighboring land pixel for respectively; (3) applying a linear unmixing model for subpixel water fraction estimation. Specifically, to automatically extract land-water pixels, the locally weighted scatter plot smoothing is firstly used to the original histogram curve of WI image . And then the Ostu threshold is derived as the start point to select land-water pixels based on histogram of the WI image with the land threshold and water threshold determination through the slopes of histogram curve . Based on the previous process at pixel level, the image is divided into three parts: water pixels, land pixels, and mixed land-water pixels. Then the spectral mixture analysis (SMA) is applied to land-water mixed pixels for water fraction estimation at subpixel level. With the assumption that the endmember signature of a target pixel should be more similar to adjacent pixels due to spatial dependence, the endmember of water and land are determined

  19. Efficient single-pixel multispectral imaging via non-mechanical spatio-spectral modulation

    PubMed Central

    Li, Ziwei; Suo, Jinli; Hu, Xuemei; Deng, Chao; Fan, Jingtao; Dai, Qionghai

    2017-01-01

    Combining spectral imaging with compressive sensing (CS) enables efficient data acquisition by fully utilizing the intrinsic redundancies in natural images. Current compressive multispectral imagers, which are mostly based on array sensors (e.g, CCD or CMOS), suffer from limited spectral range and relatively low photon efficiency. To address these issues, this paper reports a multispectral imaging scheme with a single-pixel detector. Inspired by the spatial resolution redundancy of current spatial light modulators (SLMs) relative to the target reconstruction, we design an all-optical spectral splitting device to spatially split the light emitted from the object into several counterparts with different spectrums. Separated spectral channels are spatially modulated simultaneously with individual codes by an SLM. This no-moving-part modulation ensures a stable and fast system, and the spatial multiplexing ensures an efficient acquisition. A proof-of-concept setup is built and validated for 8-channel multispectral imaging within 420~720 nm wavelength range on both macro and micro objects, showing a potential for efficient multispectral imager in macroscopic and biomedical applications. PMID:28128300

  20. Efficient single-pixel multispectral imaging via non-mechanical spatio-spectral modulation.

    PubMed

    Li, Ziwei; Suo, Jinli; Hu, Xuemei; Deng, Chao; Fan, Jingtao; Dai, Qionghai

    2017-01-27

    Combining spectral imaging with compressive sensing (CS) enables efficient data acquisition by fully utilizing the intrinsic redundancies in natural images. Current compressive multispectral imagers, which are mostly based on array sensors (e.g, CCD or CMOS), suffer from limited spectral range and relatively low photon efficiency. To address these issues, this paper reports a multispectral imaging scheme with a single-pixel detector. Inspired by the spatial resolution redundancy of current spatial light modulators (SLMs) relative to the target reconstruction, we design an all-optical spectral splitting device to spatially split the light emitted from the object into several counterparts with different spectrums. Separated spectral channels are spatially modulated simultaneously with individual codes by an SLM. This no-moving-part modulation ensures a stable and fast system, and the spatial multiplexing ensures an efficient acquisition. A proof-of-concept setup is built and validated for 8-channel multispectral imaging within 420~720 nm wavelength range on both macro and micro objects, showing a potential for efficient multispectral imager in macroscopic and biomedical applications.

  1. Efficient single-pixel multispectral imaging via non-mechanical spatio-spectral modulation

    NASA Astrophysics Data System (ADS)

    Li, Ziwei; Suo, Jinli; Hu, Xuemei; Deng, Chao; Fan, Jingtao; Dai, Qionghai

    2017-01-01

    Combining spectral imaging with compressive sensing (CS) enables efficient data acquisition by fully utilizing the intrinsic redundancies in natural images. Current compressive multispectral imagers, which are mostly based on array sensors (e.g, CCD or CMOS), suffer from limited spectral range and relatively low photon efficiency. To address these issues, this paper reports a multispectral imaging scheme with a single-pixel detector. Inspired by the spatial resolution redundancy of current spatial light modulators (SLMs) relative to the target reconstruction, we design an all-optical spectral splitting device to spatially split the light emitted from the object into several counterparts with different spectrums. Separated spectral channels are spatially modulated simultaneously with individual codes by an SLM. This no-moving-part modulation ensures a stable and fast system, and the spatial multiplexing ensures an efficient acquisition. A proof-of-concept setup is built and validated for 8-channel multispectral imaging within 420~720 nm wavelength range on both macro and micro objects, showing a potential for efficient multispectral imager in macroscopic and biomedical applications.

  2. Imaging of Ra-223 with a small-pixel CdTe detector

    NASA Astrophysics Data System (ADS)

    Scuffham, J. W.; Pani, S.; Seller, P.; Sellin, P. J.; Veale, M. C.; Wilson, M. D.; Cernik, R. J.

    2015-01-01

    Ra-223 Dichloride (Xofigo™) is a promising new radiopharmaceutical offering survival benefit and palliation of painful bone metastases in patients with hormone-refractory prostate cancer [1]. The response to radionuclide therapy and toxicity are directly linked to the absorbed radiation doses to the tumour and organs at risk respectively. Accurate dosimetry necessitates quantitative imaging of the biodistribution and kinetics of the radiopharmaceutical. Although primarily an alpha-emitter, Ra-223 also has some low-abundance X-ray and gamma emissions, which enable imaging of the biodistribution in the patient. However, the low spectral resolution of conventional gamma camera detectors makes in-vivo imaging of Ra-223 challenging. In this work, we present spectra and image data of anthropomorphic phantoms containing Ra-223 acquired with a small-pixel CdTe detector (HEXITEC) [2] with a pinhole collimator. Comparison is made with similar data acquired using a clinical gamma camera. The results demonstrate the advantages of the solid state detector in terms of scatter rejection and quantitative accuracy of the images. However, optimised collimation is needed in order for the sensitivity to rival current clinical systems. As different dosage levels and administration regimens for this drug are explored in current clinical trials, there is a clear need to develop improved imaging technologies that will enable personalised treatments to be designed for patients.

  3. Optical frequency comb profilometry based on a single-pixel phase imaging

    NASA Astrophysics Data System (ADS)

    Makhtar, Nabila; Pham, Quang Duc; Mizutani, Yasuhiro; Hayasaki, Yoshio

    2016-08-01

    In this research, we introduce a new system based on the ghost imaging, for measuring the surface profile of an object using optical frequency comb laser and a single-pixel camera. The optical frequency comb laser was used to record the relative phase of the object precisely whilst the ghost imaging technique was applied to reconstruct the object's profile. The effect of using a mask on the parameters such as number of object point, number of measurements and sparse number related to the complexity of the object for reconstruction was studied by a simulation. The performance of the system strongly depends on the design of the mask. The random mask and the Hadamard mask were used to estimate the performances in the optical frequency comb profilometry.

  4. Urban Image Classification: Per-Pixel Classifiers, Sub-Pixel Analysis, Object-Based Image Analysis, and Geospatial Methods. 10; Chapter

    NASA Technical Reports Server (NTRS)

    Myint, Soe W.; Mesev, Victor; Quattrochi, Dale; Wentz, Elizabeth A.

    2013-01-01

    Remote sensing methods used to generate base maps to analyze the urban environment rely predominantly on digital sensor data from space-borne platforms. This is due in part from new sources of high spatial resolution data covering the globe, a variety of multispectral and multitemporal sources, sophisticated statistical and geospatial methods, and compatibility with GIS data sources and methods. The goal of this chapter is to review the four groups of classification methods for digital sensor data from space-borne platforms; per-pixel, sub-pixel, object-based (spatial-based), and geospatial methods. Per-pixel methods are widely used methods that classify pixels into distinct categories based solely on the spectral and ancillary information within that pixel. They are used for simple calculations of environmental indices (e.g., NDVI) to sophisticated expert systems to assign urban land covers. Researchers recognize however, that even with the smallest pixel size the spectral information within a pixel is really a combination of multiple urban surfaces. Sub-pixel classification methods therefore aim to statistically quantify the mixture of surfaces to improve overall classification accuracy. While within pixel variations exist, there is also significant evidence that groups of nearby pixels have similar spectral information and therefore belong to the same classification category. Object-oriented methods have emerged that group pixels prior to classification based on spectral similarity and spatial proximity. Classification accuracy using object-based methods show significant success and promise for numerous urban 3 applications. Like the object-oriented methods that recognize the importance of spatial proximity, geospatial methods for urban mapping also utilize neighboring pixels in the classification process. The primary difference though is that geostatistical methods (e.g., spatial autocorrelation methods) are utilized during both the pre- and post

  5. An investigation of signal performance enhancements achieved through innovative pixel design across several generations of indirect detection, active matrix, flat-panel arrays

    PubMed Central

    Antonuk, Larry E.; Zhao, Qihua; El-Mohri, Youcef; Du, Hong; Wang, Yi; Street, Robert A.; Ho, Jackson; Weisfield, Richard; Yao, William

    2009-01-01

    Active matrix flat-panel imager (AMFPI) technology is being employed for an increasing variety of imaging applications. An important element in the adoption of this technology has been significant ongoing improvements in optical signal collection achieved through innovations in indirect detection array pixel design. Such improvements have a particularly beneficial effect on performance in applications involving low exposures and∕or high spatial frequencies, where detective quantum efficiency is strongly reduced due to the relatively high level of additive electronic noise compared to signal levels of AMFPI devices. In this article, an examination of various signal properties, as determined through measurements and calculations related to novel array designs, is reported in the context of the evolution of AMFPI pixel design. For these studies, dark, optical, and radiation signal measurements were performed on prototype imagers incorporating a variety of increasingly sophisticated array designs, with pixel pitches ranging from 75 to 127 μm. For each design, detailed measurements of fundamental pixel-level properties conducted under radiographic and fluoroscopic operating conditions are reported and the results are compared. A series of 127 μm pitch arrays employing discrete photodiodes culminated in a novel design providing an optical fill factor of ∼80% (thereby assuring improved x-ray sensitivity), and demonstrating low dark current, very low charge trapping and charge release, and a large range of linear signal response. In two of the designs having 75 and 90 μm pitches, a novel continuous photodiode structure was found to provide fill factors that approach the theoretical maximum of 100%. Both sets of novel designs achieved large fill factors by employing architectures in which some, or all of the photodiode structure was elevated above the plane of the pixel addressing transistor. Generally, enhancement of the fill factor in either discrete or continuous

  6. Sub-pixel flood inundation mapping from multispectral remotely sensed images based on discrete particle swarm optimization

    NASA Astrophysics Data System (ADS)

    Li, Linyi; Chen, Yun; Yu, Xin; Liu, Rui; Huang, Chang

    2015-03-01

    The study of flood inundation is significant to human life and social economy. Remote sensing technology has provided an effective way to study the spatial and temporal characteristics of inundation. Remotely sensed images with high temporal resolutions are widely used in mapping inundation. However, mixed pixels do exist due to their relatively low spatial resolutions. One of the most popular approaches to resolve this issue is sub-pixel mapping. In this paper, a novel discrete particle swarm optimization (DPSO) based sub-pixel flood inundation mapping (DPSO-SFIM) method is proposed to achieve an improved accuracy in mapping inundation at a sub-pixel scale. The evaluation criterion for sub-pixel inundation mapping is formulated. The DPSO-SFIM algorithm is developed, including particle discrete encoding, fitness function designing and swarm search strategy. The accuracy of DPSO-SFIM in mapping inundation at a sub-pixel scale was evaluated using Landsat ETM + images from study areas in Australia and China. The results show that DPSO-SFIM consistently outperformed the four traditional SFIM methods in these study areas. A sensitivity analysis of DPSO-SFIM was also carried out to evaluate its performances. It is hoped that the results of this study will enhance the application of medium-low spatial resolution images in inundation detection and mapping, and thereby support the ecological and environmental studies of river basins.

  7. Large Scale Image Retrieval in Urban Environments with Pixel Accurate Image Tagging

    DTIC Science & Technology

    2011-12-16

    image is used to compute a homography transformation which can then be used to transfer tag information associated with points in the database image onto...reality applications, which for the most part do not currently utilize visual scene information 1 . Image retrieval systems where user generated...Assuming a good image match is retrieved 6 , we must transfer the tag information from the matched database image to the query image. As our system is

  8. Multi-Scale Pixel-Based Image Fusion Using Multivariate Empirical Mode Decomposition

    PubMed Central

    Rehman, Naveed ur; Ehsan, Shoaib; Abdullah, Syed Muhammad Umer; Akhtar, Muhammad Jehanzaib; Mandic, Danilo P.; McDonald-Maier, Klaus D.

    2015-01-01

    A novel scheme to perform the fusion of multiple images using the multivariate empirical mode decomposition (MEMD) algorithm is proposed. Standard multi-scale fusion techniques make a priori assumptions regarding input data, whereas standard univariate empirical mode decomposition (EMD)-based fusion techniques suffer from inherent mode mixing and mode misalignment issues, characterized respectively by either a single intrinsic mode function (IMF) containing multiple scales or the same indexed IMFs corresponding to multiple input images carrying different frequency information. We show that MEMD overcomes these problems by being fully data adaptive and by aligning common frequency scales from multiple channels, thus enabling their comparison at a pixel level and subsequent fusion at multiple data scales. We then demonstrate the potential of the proposed scheme on a large dataset of real-world multi-exposure and multi-focus images and compare the results against those obtained from standard fusion algorithms, including the principal component analysis (PCA), discrete wavelet transform (DWT) and non-subsampled contourlet transform (NCT). A variety of image fusion quality measures are employed for the objective evaluation of the proposed method. We also report the results of a hypothesis testing approach on our large image dataset to identify statistically-significant performance differences. PMID:26007714

  9. The MuPix high voltage monolithic active pixel sensor for the Mu3e experiment

    NASA Astrophysics Data System (ADS)

    Augustin, H.; Berger, N.; Bravar, S.; Corrodi, S.; Damyanova, A.; Förster, F.; Gredig, R.; Herkert, A.; Huang, Q.; Huth, L.; Kiehn, M.; Kozlinskiy, A.; Maldaner, S.; Perić, I.; Philipp, R.; Robmann, P.; Schöning, A.; Shrestha, S.; vom Bruch, D.; Weber, T.; Wiedner, D.

    2015-03-01

    Mu3e is a novel experiment searching for charged lepton flavor violation in the rare decay μ → eee. In order to reduce background by up to 16 orders of magnitude, decay vertex position, decay time and particle momenta have to be measured precisely. A pixel tracker based on 50 μm thin high voltage monolithic active pixel sensors (HV-MAPS) in a magnetic field will deliver precise vertex and momentum information. Test beam results like an excellent efficiency of >99.5% and a time resolution of better than 16.6 ns obtained with the MuPix HV-MAPS chip developed for the Mu3e pixel tracker are presented.

  10. Low-power priority Address-Encoder and Reset-Decoder data-driven readout for Monolithic Active Pixel Sensors for tracker system

    NASA Astrophysics Data System (ADS)

    Yang, P.; Aglieri, G.; Cavicchioli, C.; Chalmet, P. L.; Chanlek, N.; Collu, A.; Gao, C.; Hillemanns, H.; Junique, A.; Kofarago, M.; Keil, M.; Kugathasan, T.; Kim, D.; Kim, J.; Lattuca, A.; Marin Tobon, C. A.; Marras, D.; Mager, M.; Martinengo, P.; Mazza, G.; Mugnier, H.; Musa, L.; Puggioni, C.; Rousset, J.; Reidt, F.; Riedler, P.; Snoeys, W.; Siddhanta, S.; Usai, G.; van Hoorne, J. W.; Yi, J.

    2015-06-01

    Active Pixel Sensors used in High Energy Particle Physics require low power consumption to reduce the detector material budget, low integration time to reduce the possibilities of pile-up and fast readout to improve the detector data capability. To satisfy these requirements, a novel Address-Encoder and Reset-Decoder (AERD) asynchronous circuit for a fast readout of a pixel matrix has been developed. The AERD data-driven readout architecture operates the address encoding and reset decoding based on an arbitration tree, and allows us to readout only the hit pixels. Compared to the traditional readout structure of the rolling shutter scheme in Monolithic Active Pixel Sensors (MAPS), AERD can achieve a low readout time and a low power consumption especially for low hit occupancies. The readout is controlled at the chip periphery with a signal synchronous with the clock, allows a good digital and analogue signal separation in the matrix and a reduction of the power consumption. The AERD circuit has been implemented in the TowerJazz 180 nm CMOS Imaging Sensor (CIS) process with full complementary CMOS logic in the pixel. It works at 10 MHz with a matrix height of 15 mm. The energy consumed to read out one pixel is around 72 pJ. A scheme to boost the readout speed to 40 MHz is also discussed. The sensor chip equipped with AERD has been produced and characterised. Test results including electrical beam measurement are presented.

  11. Imaging in laser spectroscopy by a single-pixel camera based on speckle patterns

    NASA Astrophysics Data System (ADS)

    Žídek, K.; Václavík, J.

    2016-11-01

    Compressed sensing (CS) is a branch of computational optics able to reconstruct an image (or any other information) from a reduced number of measurements - thus significantly saving measurement time. It relies on encoding the detected information by a random pattern and consequent mathematical reconstruction. CS can be the enabling step to carry out imaging in many time-consuming measurements. The critical step in CS experiments is the method to invoke encoding by a random mask. Complex devices and relay optics are commonly used for the purpose. We present a new approach of creating the random mask by using laser speckles from coherent laser light passing through a diffusor. This concept is especially powerful in laser spectroscopy, where it does not require any complicated modification of the current techniques. The main advantage consist in the unmatched simplicity of the random pattern generation and a versatility of the pattern resolution. Unlike in the case of commonly used random masks, here the pattern fineness can be adjusted by changing the laser spot size being diffused. We demonstrate the pattern tuning together with the connected changes in the pattern statistics. In particular, the issue of patterns orthogonality, which is important for the CS applications, is discussed. Finally, we demonstrate on a set of 200 acquired speckle patterns that the concept can be successfully employed for single-pixel camera imaging. We discuss requirements on detector noise for the image reconstruction.

  12. Linear fitting of multi-threshold counting data with a pixel-array detector for spectral X-ray imaging

    PubMed Central

    Muir, Ryan D.; Pogranichney, Nicholas R.; Muir, J. Lewis; Sullivan, Shane Z.; Battaile, Kevin P.; Mulichak, Anne M.; Toth, Scott J.; Keefe, Lisa J.; Simpson, Garth J.

    2014-01-01

    Experiments and modeling are described to perform spectral fitting of multi-threshold counting measurements on a pixel-array detector. An analytical model was developed for describing the probability density function of detected voltage in X-ray photon-counting arrays, utilizing fractional photon counting to account for edge/corner effects from voltage plumes that spread across multiple pixels. Each pixel was mathematically calibrated by fitting the detected voltage distributions to the model at both 13.5 keV and 15.0 keV X-ray energies. The model and established pixel responses were then exploited to statistically recover images of X-ray intensity as a function of X-ray energy in a simulated multi-wavelength and multi-counting threshold experiment. PMID:25178010

  13. A stimulated Raman scattering imager using high-speed lateral electric field modulator and lock-in pixels amplifiers

    NASA Astrophysics Data System (ADS)

    Mars, Kamel; Guseul, Beak; Han, Sang Man; Takasawa, Taishi; Yasutomi, Keita; Kagawa, Keiichiro; Hashimoto, Mamoru; Kawahito, Shoji

    2014-03-01

    A high speed Lateral Electric Field Modulator (LEFM) and lock-in pixels amplifiers for stimulated Raman scattering (SRS)imager is presented. Since the generated signal from the SRS process is very small compared to the offset signal, a technique suitable for extracting and amplifying the SRS signal is needed. The offset can be canceled by tuning the phase delay between the demodulated pixel output signal and the sampling clock. The small SRS signal in large offset is amplified by the differential integration. The proposed technique has been investigated with an implementation of 64x8 pixels array using a pinned photodiode LEFM an lock-in pixels amplifiers. Very small signal can be extracted from large offset signal. A ratio of the detected small SRS to offset signal of less 10-5 is achieved.

  14. Heavily irradiated N-in-p thin planar pixel sensors with and without active edges

    NASA Astrophysics Data System (ADS)

    Terzo, S.; Andricek, L.; Macchiolo, A.; Moser, H. G.; Nisius, R.; Richter, R. H.; Weigell, P.

    2014-05-01

    We present the results of the characterization of silicon pixel modules employing n-in-p planar sensors with an active thickness of 150 μm, produced at MPP/HLL, and 100-200 μm thin active edge sensor devices, produced at VTT in Finland. These thin sensors are designed as candidates for the ATLAS pixel detector upgrade to be operated at the HL-LHC, as they ensure radiation hardness at high fluences. They are interconnected to the ATLAS FE-I3 and FE-I4 read-out chips. Moreover, the n-in-p technology only requires a single side processing and thereby it is a cost-effective alternative to the n-in-n pixel technology presently employed in the LHC experiments. High precision beam test measurements of the hit efficiency have been performed on these devices both at the CERN SpS and at DESY, Hamburg. We studied the behavior of these sensors at different bias voltages and different beam incident angles up to the maximum one expected for the new Insertable B-Layer of ATLAS and for HL-LHC detectors. Results obtained with 150 μm thin sensors, assembled with the new ATLAS FE-I4 chip and irradiated up to a fluence of 4 × 1015 neq/cm2, show that they are excellent candidates for larger radii of the silicon pixel tracker in the upgrade of the ATLAS detector at HL-LHC. In addition, the active edge technology of the VTT devices maximizes the active area of the sensor and reduces the material budget to suit the requirements for the innermost layers. The edge pixel performance of VTT modules has been investigated at beam test experiments and the analysis after irradiation up to a fluence of 5 × 1015 neq/cm2 has been performed using radioactive sources in the laboratory.

  15. Improvement in pixel signal uniformity of polycrystalline mercuric iodide films for digital X-ray imaging

    NASA Astrophysics Data System (ADS)

    Oh, Kyungmin; Kim, Jinseon; Shin, Jungwook; Heo, Seunguk; Cho, Gyuseok; Kim, Daekuk; Park, Jigoon; Nam, Sanghee

    2014-03-01

    We investigated polycrystalline mercuric iodide (HgI2) that exhibits uniform pixel signals for its use in digital X-ray imaging. To fabricate thin polycrystalline HgI2 films, the particle-in-binder (PIB) method is used because it enables the fabrication of X-ray conversion films at a low temperature and a normal pressure. Moreover, it has a large-scale deposition capacity at a low cost. Although the thin layers fabricated by the PIB method have such advantages, they are chemically unstable and show poor reproducibility and nonuniform X-ray response. To solve these problems, in this study, additional physical and chemical treatments were performed along with the PIB method after taking the size confinement effect of photoconductive particles into consideration. Morphological and electrical properties were measured to investigate the effects of the physical and chemical treatments.

  16. Method of acquiring an image from an optical structure having pixels with dedicated readout circuits

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R. (Inventor); Mendis, Sunetra (Inventor); Kemeny, Sabrina E. (Inventor)

    2006-01-01

    An imaging device formed as a monolithic complementary metal oxide semiconductor integrated circuit in an industry standard complementary metal oxide semiconductor process, the integrated circuit including a focal plane array of pixel cells, each one of the cells including a photogate overlying the substrate for accumulating photo-generated charge in an underlying portion of the substrate, a readout circuit including at least an output field effect transistor formed in the substrate, and a charge coupled device section formed on the substrate adjacent the photogate having a sensing node connected to the output transistor and at least one charge coupled device stage for transferring charge from the underlying portion of the substrate to the sensing node.

  17. Design Studies of a CZT-based Detector Combined with a Pixel-Geometry-Matching Collimator for SPECT Imaging

    PubMed Central

    Weng, Fenghua; Bagchi, Srijeeta; Huang, Qiu; Seo, Youngho

    2014-01-01

    Single Photon Emission Computed Tomography (SPECT) suffers limited efficiency due to the need for collimators. Collimator properties largely decide the data statistics and image quality. Various materials and configurations of collimators have been investigated in many years. The main thrust of our study is to evaluate the design of pixel-geometry-matching collimators to investigate their potential performances using Geant4 Monte Carlo simulations. Here, a pixel-geometry-matching collimator is defined as a collimator which is divided into the same number of pixels as the detector’s and the center of each pixel in the collimator is a one-to-one correspondence to that in the detector. The detector is made of Cadmium Zinc Telluride (CZT), which is one of the most promising materials for applications to detect hard X-rays and γ-rays due to its ability to obtain good energy resolution and high light output at room temperature. For our current project, we have designed a large-area, CZT-based gamma camera (20.192 cm×20.192 cm) with a small pixel pitch (1.60 mm). The detector is pixelated and hence the intrinsic resolution can be as small as the size of the pixel. Materials of collimator, collimator hole geometry, detection efficiency, and spatial resolution of the CZT detector combined with the pixel-matching collimator were calculated and analyzed under different conditions. From the simulation studies, we found that such a camera using rectangular holes has promising imaging characteristics in terms of spatial resolution, detection efficiency, and energy resolution. PMID:25378898

  18. Image sensor pixel with on-chip high extinction ratio polarizer based on 65-nm standard CMOS technology.

    PubMed

    Sasagawa, Kiyotaka; Shishido, Sanshiro; Ando, Keisuke; Matsuoka, Hitoshi; Noda, Toshihiko; Tokuda, Takashi; Kakiuchi, Kiyomi; Ohta, Jun

    2013-05-06

    In this study, we demonstrate a polarization sensitive pixel for a complementary metal-oxide-semiconductor (CMOS) image sensor based on 65-nm standard CMOS technology. Using such a deep-submicron CMOS technology, it is possible to design fine metal patterns smaller than the wavelengths of visible light by using a metal wire layer. We designed and fabricated a metal wire grid polarizer on a 20 × 20 μm(2) pixel for image sensor. An extinction ratio of 19.7 dB was observed at a wavelength 750 nm.

  19. A single-pixel X-ray imager concept and its application to secure radiographic inspections

    DOE PAGES

    Gilbert, Andrew J.; Miller, Brian W.; Robinson, Sean M.; ...

    2017-03-18

    Imaging technology is generally considered too invasive for arms control inspections due to the concern that it cannot properly secure sensitive features of the inspected item. But, this same sensitive information, which could include direct information on the form and function of the items under inspection, could be used for robust arms control inspections. The single-pixel X-ray imager (SPXI) is introduced as a method to make such inspections, capturing the salient spatial information of an object in a secure manner while never forming an actual image. We built this method on the theory of compressive sensing and the single pixelmore » optical camera. The performance of the system is quantified using simulated inspections of simple objects. Measures of the robustness and security of the method are introduced and used to determine how robust and secure such an inspection would be. Particularly, it is found that an inspection with low noise (<1%) and high undersampling (>256×) exhibits high robustness and security.« less

  20. A novel source-drain follower for monolithic active pixel sensors

    NASA Astrophysics Data System (ADS)

    Gao, C.; Aglieri, G.; Hillemanns, H.; Huang, G.; Junique, A.; Keil, M.; Kim, D.; Kofarago, M.; Kugathasan, T.; Mager, M.; Marin Tobon, C. A.; Martinengo, P.; Mugnier, H.; Musa, L.; Lee, S.; Reidt, F.; Riedler, P.; Rousset, J.; Sielewicz, K. M.; Snoeys, W.; Sun, X.; Van Hoorne, J. W.; Yang, P.

    2016-09-01

    Monolithic active pixel sensors (MAPS) receive interest in tracking applications in high energy physics as they integrate sensor and readout electronics in one silicon die with potential for lower material budget and cost, and better performance. Source followers (SFs) are widely used for MAPS readout: they increase charge conversion gain 1/Ceff or decrease the effective sensing node capacitance Ceff because the follower action compensates part of the input capacitance. Charge conversion gain is critical for analog power consumption and therefore for material budget in tracking applications, and also has direct system impact. This paper presents a novel source-drain follower (SDF), where both source and drain follow the gate potential improving charge conversion gain. For the inner tracking system (ITS) upgrade of the ALICE experiment at CERN, low material budget is a primary requirement. The SDF circuit was studied as part of the effort to optimize the effective capacitance of the sensing node. The collection electrode, input transistor and routing metal all contribute to Ceff. Reverse sensor bias reduces the collection electrode capacitance. The novel SDF circuit eliminates the contribution of the input transistor to Ceff, reduces the routing contribution if additional shielding is introduced, provides a way to estimate the capacitance of the sensor itself, and has a voltage gain closer to unity than the standard SF. The SDF circuit has a somewhat larger area with a somewhat smaller bandwidth, but this is acceptable in most cases. A test chip, manufactured in a 180 nm CMOS image sensor process, implements small prototype pixel matrices in different flavors to compare the standard SF to the novel SF and to the novel SF with additional shielding. The effective sensing node capacitance was measured using a 55Fe source. Increasing reverse substrate bias from -1 V to -6 V reduces Ceff by 38% and the equivalent noise charge (ENC) by 22% for the standard SF. The SDF

  1. A new approach for surface water change detection: Integration of pixel level image fusion and image classification techniques

    NASA Astrophysics Data System (ADS)

    Rokni, Komeil; Ahmad, Anuar; Solaimani, Karim; Hazini, Sharifeh

    2015-02-01

    Normally, to detect surface water changes, water features are extracted individually using multi-temporal satellite data, and then analyzed and compared to detect their changes. This study introduced a new approach for surface water change detection, which is based on integration of pixel level image fusion and image classification techniques. The proposed approach has the advantages of producing a pansharpened multispectral image, simultaneously highlighting the changed areas, as well as providing a high accuracy result. In doing so, various fusion techniques including Modified IHS, High Pass Filter, Gram Schmidt, and Wavelet-PC were investigated to merge the multi-temporal Landsat ETM+ 2000 and TM 2010 images to highlight the changes. The suitability of the resulting fused images for change detection was evaluated using edge detection, visual interpretation, and quantitative analysis methods. Subsequently, artificial neural network (ANN), support vector machine (SVM), and maximum likelihood (ML) classification techniques were applied to extract and map the highlighted changes. Furthermore, the applicability of the proposed approach for surface water change detection was evaluated in comparison with some common change detection methods including image differencing, principal components analysis, and post classification comparison. The results indicate that Lake Urmia lost about one third of its surface area in the period 2000-2010. The results illustrate the effectiveness of the proposed approach, especially Gram Schmidt-ANN and Gram Schmidt-SVM for surface water change detection.

  2. THE IMAGING PROPERTIES OF THE GAS PIXEL DETECTOR AS A FOCAL PLANE POLARIMETER

    SciTech Connect

    Fabiani, S.; Costa, E.; Del Monte, E.; Muleri, F.; Soffitta, P.; Rubini, A.; Bellazzini, R.; Brez, A.; De Ruvo, L.; Minuti, M.; Pinchera, M.; Sgró, C.; Spandre, G.; Spiga, D.; Tagliaferri, G.; Pareschi, G.; Basso, S.; Citterio, O.; Burwitz, V.; Burkert, W.; and others

    2014-06-01

    X-rays are particularly suited to probing the physics of extreme objects. However, despite the enormous improvements of X-ray astronomy in imaging, spectroscopy, and timing, polarimetry remains largely unexplored. We propose the photoelectric polarimeter Gas Pixel Detector (GPD) as a candidate instrument to fill the gap created by more than 30 yr without measurements. The GPD, in the focus of a telescope, will increase the sensitivity of orders of magnitude. Moreover, since it can measure the energy, the position, the arrival time, and the polarization angle of every single photon, it allows us to perform polarimetry of subsets of data singled out from the spectrum, the light curve, or an image of the source. The GPD has an intrinsic, very fine imaging capability, and in this work we report on the calibration campaign carried out in 2012 at the PANTER X-ray testing facility of the Max-Planck-Institut für extraterrestrische Physik of Garching (Germany) in which, for the first time, we coupled it with a JET-X optics module with a focal length of 3.5 m and an angular resolution of 18 arcsec at 4.5 keV. This configuration was proposed in 2012 aboard the X-ray Imaging Polarimetry Explorer (XIPE) in response to the ESA call for a small mission. We derived the imaging and polarimetric performance for extended sources like pulsar wind nebulae and supernova remnants as case studies for the XIPE configuration and also discuss possible improvements by coupling the detector with advanced optics that have a finer angular resolution and larger effective areas to study extended objects with more detail.

  3. Three-dimensional imaging with simultaneous reproduction of two image elements in one display pixel by information-dependent polarization coding.

    PubMed

    Ezhov, Vasily

    2010-05-20

    Information-dependent (active) polarization encoding can be used to simultaneously present two image-resolvable elements [elements of left and right views of a three-dimensional (3D) scene] in a single display pixel. Polarization decoding, with the help of passive polarization filters, makes it possible to separate elements of left and right views and to observe them independently by left and right eyes. In this paper the basic theory of such 3D displays is developed. The relevant solutions of the general equation of light elliptical polarization are obtained in all important cases: cases of controlled birefringence and/or optical activity as three basic controlled polarization encoders. The obtained formulas are essentially the forms of signals that should control the values of birefringence and optical activity to realize the required polarization encoding. Optical schemes of flat-panel direct-view stereoscopic and autostereoscopic displays with the use of liquid crystal polarization encoding matrices are considered.

  4. Chlorophyll concentration estimates for coastal water using pixel-based atmospheric correction of Landsat images

    NASA Astrophysics Data System (ADS)

    Kouba, Eric

    Ocean color analysis is more challenging for coastal regions than the global ocean due the effects of optical brightness, shallow and turbid water, higher phytoplankton growth rates, and the complex geometry of coastal bays and estuaries. Also, one of the key atmospheric correction assumptions (zero water leaving radiance in the near infrared) is not valid for these complex conditions. This makes it difficult to estimate the spectral radiance noise caused by atmospheric aerosols, which can vary rapidly with time and space. This study conducts pixel-based atmospheric correction of Landsat-7 ETM+ images over the Texas coast. Precise satellite orbit data, operational weather data, and climate data are combined to create interpolated arrays of viewing angles and atmospheric profiles. These arrays vary with time and location, allowing calculation of the Rayleigh and aerosol radiances separately for all pixels. The resulting normalized water-leaving radiances are then compared with in situ chlorophyll fluorescence measurements from five locations inside a set of Texas coastal bays: the Mission-Aransas National Estuarine Research Reserve. Curve-fitting analysis shows it is possible to estimate chlorophyll-a surface area concentrations by using ETM+ water-leaving radiance values and a third-order polynomial equation. Two pairs of ETM+ bands are identified as inputs (Bands 1 and 3, and the Log10 values of Bands 3 and 4), both achieving good performance (R2 of 0.69). Further research efforts are recommended to obtain additional data, identify better curve fitting equations, and potentially extend the radiative transfer model into the water column.

  5. Investigating the effect of pixel size of high spatial resolution FTIR imaging for detection of colorectal cancer

    NASA Astrophysics Data System (ADS)

    Lloyd, G. R.; Nallala, J.; Stone, N.

    2016-03-01

    FTIR is a well-established technique and there is significant interest in applying this technique to medical diagnostics e.g. to detect cancer. The introduction of focal plane array (FPA) detectors means that FTIR is particularly suited to rapid imaging of biopsy sections as an adjunct to digital pathology. Until recently however each pixel in the image has been limited to a minimum of 5.5 µm which results in a comparatively low magnification image or histology applications and potentially the loss of important diagnostic information. The recent introduction of higher magnification optics gives image pixels that cover approx. 1.1 µm. This reduction in image pixel size gives images of higher magnification and improved spatial detail can be observed. However, the effect of increasing the magnification on spectral quality and the ability to discriminate between disease states is not well studied. In this work we test the discriminatory performance of FTIR imaging using both standard (5.5 µm) and high (1.1 µm) magnification for the detection of colorectal cancer and explore the effect of binning to degrade high resolution images to determine whether similar diagnostic information and performance can be obtained using both magnifications. Results indicate that diagnostic performance using high magnification may be reduced as compared to standard magnification when using existing multivariate approaches. Reduction of the high magnification data to standard magnification via binning can potentially recover some of the lost performance.

  6. Dual-mode optical microscope based on single-pixel imaging

    NASA Astrophysics Data System (ADS)

    Rodríguez, A. D.; Clemente, P.; Tajahuerce, E.; Lancis, J.

    2016-07-01

    We demonstrate an inverted microscope that can image specimens in both reflection and transmission modes simultaneously with a single light source. The microscope utilizes a digital micromirror device (DMD) for patterned illumination altogether with two single-pixel photosensors for efficient light detection. The system, a scan-less device with no moving parts, works by sequential projection of a set of binary intensity patterns onto the sample that are codified onto a modified commercial DMD. Data to be displayed are geometrically transformed before written into a memory cell to cancel optical artifacts coming from the diamond-like shaped structure of the micromirror array. The 24-bit color depth of the display is fully exploited to increase the frame rate by a factor of 24, which makes the technique practicable for real samples. Our commercial DMD-based LED-illumination is cost effective and can be easily coupled as an add-on module for already existing inverted microscopes. The reflection and transmission information provided by our dual microscope complement each other and can be useful for imaging non-uniform samples and to prevent self-shadowing effects.

  7. Development of Electron Tracking Compton Camera using micro pixel gas chamber for medical imaging

    NASA Astrophysics Data System (ADS)

    Kabuki, Shigeto; Hattori, Kaori; Kohara, Ryota; Kunieda, Etsuo; Kubo, Atsushi; Kubo, Hidetoshi; Miuchi, Kentaro; Nakahara, Tadaki; Nagayoshi, Tsutomu; Nishimura, Hironobu; Okada, Yoko; Orito, Reiko; Sekiya, Hiroyuki; Shirahata, Takashi; Takada, Atsushi; Tanimori, Toru; Ueno, Kazuki

    2007-10-01

    We have developed the Electron Tracking Compton Camera (ETCC) with reconstructing the 3-D tracks of the scattered electron in Compton process for both sub-MeV and MeV gamma rays. By measuring both the directions and energies of not only the recoil gamma ray but also the scattered electron, the direction of the incident gamma ray is determined for each individual photon. Furthermore, a residual measured angle between the recoil electron and scattered gamma ray is quite powerful for the kinematical background rejection. For the 3-D tracking of the electrons, the Micro Time Projection Chamber (μ-TPC) was developed using a new type of the micro pattern gas detector. The ETCC consists of this μ-TPC (10×10×8 cm 3) and the 6×6×13 mm 3 GSO crystal pixel arrays with a flat panel photo-multiplier surrounding the μ-TPC for detecting recoil gamma rays. The ETCC provided the angular resolution of 6.6° (FWHM) at 364 keV of 131I. A mobile ETCC for medical imaging, which is fabricated in a 1 m cubic box, has been operated since October 2005. Here, we present the imaging results for the line sources and the phantom of human thyroid gland using 364 keV gamma rays of 131I.

  8. Solid-state image sensor with focal-plane digital photon-counting pixel array

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R. (Inventor); Pain, Bedabrata (Inventor)

    1995-01-01

    A photosensitive layer such as a-Si for a UV/visible wavelength band is provided for low light level imaging with at least a separate CMOS amplifier directly connected to each PIN photodetector diode to provide a focal-plane array of NxN pixels, and preferably a separate photon-counting CMOS circuit directly connected to each CMOS amplifier, although one row of counters may be time shared for reading out the photon flux rate of each diode in the array, together with a buffer memory for storing all rows of the NxN image frame before transfer to suitable storage. All CMOS circuitry is preferably fabricated in the same silicon layer as the PIN photodetector diode for a monolithic structure, but when the wavelength band of interest requires photosensitive material different from silicon, the focal-plane array may be fabricated separately on a different semiconductor layer bump-bonded or otherwise bonded for a virtually monolithic structure with one free terminal of each diode directly connected to the input terminal of its CMOS amplifier and digital counter for integration of the photon flux rate at each photodetector of the array.

  9. Automated segmentation by pixel classification of retinal layers in ophthalmic OCT images

    PubMed Central

    Vermeer, K. A.; van der Schoot, J.; Lemij, H. G.; de Boer, J. F.

    2011-01-01

    Current OCT devices provide three-dimensional (3D) in-vivo images of the human retina. The resulting very large data sets are difficult to manually assess. Automated segmentation is required to automatically process the data and produce images that are clinically useful and easy to interpret. In this paper, we present a method to segment the retinal layers in these images. Instead of using complex heuristics to define each layer, simple features are defined and machine learning classifiers are trained based on manually labeled examples. When applied to new data, these classifiers produce labels for every pixel. After regularization of the 3D labeled volume to produce a surface, this results in consistent, three-dimensionally segmented layers that match known retinal morphology. Six labels were defined, corresponding to the following layers: Vitreous, retinal nerve fiber layer (RNFL), ganglion cell layer & inner plexiform layer, inner nuclear layer & outer plexiform layer, photoreceptors & retinal pigment epithelium and choroid. For both normal and glaucomatous eyes that were imaged with a Spectralis (Heidelberg Engineering) OCT system, the five resulting interfaces were compared between automatic and manual segmentation. RMS errors for the top and bottom of the retina were between 4 and 6 μm, while the errors for intra-retinal interfaces were between 6 and 15 μm. The resulting total retinal thickness maps corresponded with known retinal morphology. RNFL thickness maps were compared to GDx (Carl Zeiss Meditec) thickness maps. Both maps were mostly consistent but local defects were better visualized in OCT-derived thickness maps. PMID:21698034

  10. Dual-gate photo thin-film transistor: a “smart” pixel for high- resolution and low-dose X-ray imaging

    NASA Astrophysics Data System (ADS)

    Wang, Kai; Ou, Hai; Chen, Jun

    2015-06-01

    Since its emergence a decade ago, amorphous silicon flat panel X-ray detector has established itself as a ubiquitous platform for an array of digital radiography modalities. The fundamental building block of a flat panel detector is called a pixel. In all current pixel architectures, sensing, storage, and readout are unanimously kept separate, inevitably compromising resolution by increasing pixel size. To address this issue, we hereby propose a “smart” pixel architecture where the aforementioned three components are combined in a single dual-gate photo thin-film transistor (TFT). In other words, the dual-gate photo TFT itself functions as a sensor, a storage capacitor, and a switch concurrently. Additionally, by harnessing the amplification effect of such a thin-film transistor, we for the first time created a single-transistor active pixel sensor. The proof-of-concept device had a W/L ratio of 250μm/20μm and was fabricated using a simple five-mask photolithography process, where a 130nm transparent ITO was used as the top photo gate, and a 200nm amorphous silicon as the absorbing channel layer. The preliminary results demonstrated that the photocurrent had been increased by four orders of magnitude due to light-induced threshold voltage shift in the sub-threshold region. The device sensitivity could be simply tuned by photo gate bias to specifically target low-level light detection. The dependence of threshold voltage on light illumination indicated that a dynamic range of at least 80dB could be achieved. The "smart" pixel technology holds tremendous promise for developing high-resolution and low-dose X-ray imaging and may potentially lower the cancer risk imposed by radiation, especially among paediatric patients.

  11. Image quality improvement in megavoltage cone beam CT using an imaging beam line and a sintered pixelated array system

    SciTech Connect

    Breitbach, Elizabeth K.; Maltz, Jonathan S.; Gangadharan, Bijumon; Bani-Hashemi, Ali; Anderson, Carryn M.; Bhatia, Sudershan K.; Stiles, Jared; Edwards, Drake S.; Flynn, Ryan T.

    2011-11-15

    Purpose: To quantify the improvement in megavoltage cone beam computed tomography (MVCBCT) image quality enabled by the combination of a 4.2 MV imaging beam line (IBL) with a carbon electron target and a detector system equipped with a novel sintered pixelated array (SPA) of translucent Gd{sub 2}O{sub 2}S ceramic scintillator. Clinical MVCBCT images are traditionally acquired with the same 6 MV treatment beam line (TBL) that is used for cancer treatment, a standard amorphous Si (a-Si) flat panel imager, and the Kodak Lanex Fast-B (LFB) scintillator. The IBL produces a greater fluence of keV-range photons than the TBL, to which the detector response is more optimal, and the SPA is a more efficient scintillator than the LFB. Methods: A prototype IBL + SPA system was installed on a Siemens Oncor linear accelerator equipped with the MVision{sup TM} image guided radiation therapy (IGRT) system. A SPA strip consisting of four neighboring tiles and measuring 40 cm by 10.96 cm in the crossplane and inplane directions, respectively, was installed in the flat panel imager. Head- and pelvis-sized phantom images were acquired at doses ranging from 3 to 60 cGy with three MVCBCT configurations: TBL + LFB, IBL + LFB, and IBL + SPA. Phantom image quality at each dose was quantified using the contrast-to-noise ratio (CNR) and modulation transfer function (MTF) metrics. Head and neck, thoracic, and pelvic (prostate) cancer patients were imaged with the three imaging system configurations at multiple doses ranging from 3 to 15 cGy. The systems were assessed qualitatively from the patient image data. Results: For head and neck and pelvis-sized phantom images, imaging doses of 3 cGy or greater, and relative electron densities of 1.09 and 1.48, the CNR average improvement factors for imaging system change of TBL + LFB to IBL + LFB, IBL + LFB to IBL + SPA, and TBL + LFB to IBL + SPA were 1.63 (p < 10{sup -8}), 1.64 (p < 10{sup -13}), 2.66 (p < 10{sup -9}), respectively. For all imaging

  12. Development of active edge pixel sensors and four-side buttable modules using vertical integration technologies

    NASA Astrophysics Data System (ADS)

    Macchiolo, A.; Andricek, L.; Moser, H.-G.; Nisius, R.; Richter, R. H.; Terzo, S.; Weigell, P.

    2014-11-01

    We present an R&D activity focused on the development of novel modules for the upgrade of the ATLAS pixel system at the High Luminosity LHC (HL-LHC). The modules consist of n-in-p pixel sensors, 100 or 200 μm thick, produced at VTT (Finland) with an active edge technology, which considerably reduces the dead area at the periphery of the device. The sensors are interconnected with solder bump-bonding to the ATLAS FE-I3 and FE-I4 read-out chips, and characterised with radioactive sources and beam tests at the CERN-SPS and DESY. The results of these measurements will be discussed for devices before and after irradiation up to a fluence of 5 ×1015neq /cm2. We will also report on the R&D activity to obtain Inter Chip Vias (ICVs) on the ATLAS read-out chip in collaboration with the Fraunhofer Institute EMFT. This step is meant to prove the feasibility of the signal transport to the newly created readout pads on the backside of the chips allowing for four side buttable devices without the presently used cantilever for wire bonding. The read-out chips with ICVs will be interconnected to thin pixel sensors, 75 μm and 150 μm thick, with the Solid Liquid Interdiffusion (SLID) technology, which is an alternative to the standard solder bump-bonding.

  13. [Fractal analysis of trabecular architecture: with special reference to slice thickness and pixel size of the image].

    PubMed

    Tomomitsu, Tatsushi; Mimura, Hiroaki; Murase, Kenya; Tamada, Tsutomu; Sone, Teruki; Fukunaga, Masao

    2005-06-20

    Many analyses of bone microarchitecture using three-dimensional images of micro CT (microCT) have been reported recently. However, as extirpated bone is the subject of measurement on microCT, various kinds of information are not available clinically. Our aim is to evaluate usefulness of fractal dimension as an index of bone strength different from bone mineral density in in-vivo, to which microCT could not be applied. In this fundamental study, the relation between pixel size and the slice thickness of images was examined when fractal analysis was applied to clinical images. We examined 40 lumbar spine specimens extirpated from 16 male cadavers (30-88 years; mean age, 60.8 years). Three-dimensional images of the trabeculae of 150 slices were obtained by a microCT system under the following conditions: matrix size, 512 x 512; slice thickness, 23.2 em; and pixel size, 18.6 em. Based on images of 150 slices, images of four different matrix sizes and nine different slice thicknesses were made using public domain software (NIH Image). The threshold value for image binarization, and the relation between pixel size and the slice thickness of an image used for two-dimensional and three-dimensional fractal analyses were studied. In addition, the box counting method was used for fractal analysis. One hundred forty-five in box counting was most suitable as the threshold value for image binarization on the 256 gray levels. The correlation coefficients between two-dimensional fractal dimensions of processed images and three-dimensional fractal dimensions of original images were more than 0.9 for pixel sizes < or =148.8 microm at a slice thickness of 1 mm, and < or =74.4 microm at one of 2 mm. In terms of the relation between the three-dimensional fractal dimension of processed images and three-dimensional fractal dimension of original images, when pixel size was less than 74.4 microm, a correlation coefficient of more than 0.9 was obtained even for the maximal slice thickness

  14. Linear analysis of signal and noise characteristics of a nonlinear CMOS active-pixel detector for mammography

    NASA Astrophysics Data System (ADS)

    Yun, Seungman; Kim, Ho Kyung; Han, Jong Chul; Kam, Soohwa; Youn, Hanbean; Cunningham, Ian A.

    2017-03-01

    The imaging properties of a complementary metal-oxide-semiconductor (CMOS) active-pixel photodiode array coupled to a thin gadolinium-based granular phosphor screen with a fiber-optic faceplate are investigated. It is shown that this system has a nonlinear response at low detector exposure levels (<10 mR), resulting in an over-estimation of the detective quantum efficiency (DQE) by a factor of two in some cases. Errors in performance metrics on this scale make it difficult to compare new technologies with established systems and predict performance benchmarks that can be achieved in practice and help understand performance bottlenecks. It is shown the CMOS response is described by a power-law model that can be used to linearize image data. Linearization removed an unexpected dependence of the DQE on detector exposure level.

  15. PixelLearn

    NASA Technical Reports Server (NTRS)

    Mazzoni, Dominic; Wagstaff, Kiri; Bornstein, Benjamin; Tang, Nghia; Roden, Joseph

    2006-01-01

    PixelLearn is an integrated user-interface computer program for classifying pixels in scientific images. Heretofore, training a machine-learning algorithm to classify pixels in images has been tedious and difficult. PixelLearn provides a graphical user interface that makes it faster and more intuitive, leading to more interactive exploration of image data sets. PixelLearn also provides image-enhancement controls to make it easier to see subtle details in images. PixelLearn opens images or sets of images in a variety of common scientific file formats and enables the user to interact with several supervised or unsupervised machine-learning pixel-classifying algorithms while the user continues to browse through the images. The machinelearning algorithms in PixelLearn use advanced clustering and classification methods that enable accuracy much higher than is achievable by most other software previously available for this purpose. PixelLearn is written in portable C++ and runs natively on computers running Linux, Windows, or Mac OS X.

  16. A hyper-chaos-based image encryption algorithm using pixel-level permutation and bit-level permutation

    NASA Astrophysics Data System (ADS)

    Li, Yueping; Wang, Chunhua; Chen, Hua

    2017-03-01

    Recently, a number of chaos-based image encryption algorithms that use low-dimensional chaotic map and permutation-diffusion architecture have been proposed. However, low-dimensional chaotic map is less safe than high-dimensional chaotic system. And permutation process is independent of plaintext and diffusion process. Therefore, they cannot resist efficiently the chosen-plaintext attack and chosen-ciphertext attack. In this paper, we propose a hyper-chaos-based image encryption algorithm. The algorithm adopts a 5-D multi-wing hyper-chaotic system, and the key stream generated by hyper-chaotic system is related to the original image. Then, pixel-level permutation and bit-level permutation are employed to strengthen security of the cryptosystem. Finally, a diffusion operation is employed to change pixels. Theoretical analysis and numerical simulations demonstrate that the proposed algorithm is secure and reliable for image encryption.

  17. Development of a simplified simulation model for performance characterization of a pixellated CdZnTe multimodality imaging system.

    PubMed

    Guerra, P; Santos, A; Darambara, D G

    2008-02-21

    Current requirements of molecular imaging lead to the complete integration of complementary modalities in a single hybrid imaging system to correlate function and structure. Among the various existing detector technologies, which can be implemented to integrate nuclear modalities (PET and/or single-photon emission computed tomography with x-rays (CT) and most probably with MR, pixellated wide bandgap room temperature semiconductor detectors, such as CdZnTe and/or CdTe, are promising candidates. This paper deals with the development of a simplified simulation model for pixellated semiconductor radiation detectors, as a first step towards the performance characterization of a multimodality imaging system based on CdZnTe. In particular, this work presents a simple computational model, based on a 1D approximate solution of the Schockley-Ramo theorem, and its integration into the Geant4 application for tomographic emission (GATE) platform in order to perform accurately and, therefore, improve the simulations of pixellated detectors in different configurations with a simultaneous cathode and anode pixel readout. The model presented here is successfully validated against an existing detailed finite element simulator, the multi-geometry simulation code, with respect to the charge induced at the anode, taking into consideration interpixel charge sharing and crosstalk, and to the detector charge induction efficiency. As a final point, the model provides estimated energy spectra and time resolution for (57)Co and (18)F sources obtained with the GATE code after the incorporation of the proposed model.

  18. Demonstration of single pixel computational ghost imaging with pseudo-randomly patterned illumination from a liquid crystal display

    NASA Astrophysics Data System (ADS)

    Song, Lijun; Zhou, Cheng; Chen, Li; Wang, Xiaoguang; Cheng, Jing

    2016-11-01

    An experiment demonstrating computational ghost imaging with structured illumination and a single-pixel detector has been performed. Our experimental setup utilized a general computer for generating pseudo-random patterns on the liquid crystal display screen to illuminate a partially-transmissive object. With this similar true thermal light source, this object is imaged. The formula of the computational ghost imaging with this light source has been derived. The experimental results agree with the theoretical analysis. The liquid crystal display screen is more applicable for ghost imaging with ordinary incoherent light as the source of illumination.

  19. Time-resolved hyperspectral single-pixel camera implementation for compressive wide-field fluorescence lifetime imaging

    NASA Astrophysics Data System (ADS)

    Pian, Qi; Yao, Ruoyang; Intes, Xavier

    2016-03-01

    Single-pixel imaging based on compressive sensing theory has been a highlighted technique in the biomedical imaging field for many years. This interest has been driven by the possibility of performing microscopic or macroscopic imaging based on low-cost detector arrays, increased SNR (signal-to-noise ratio) in the acquired data sets and the ability to perform high quality image reconstruction with compressed data sets by exploiting signal sparsity. In this work, we present our recent work in implementing this technique to perform time domain fluorescence-labeled investigations in preclinical settings. More precisely, we report on our time-resolved hyperspectral single-pixel camera for fast, wide-field mapping of molecular labels and lifetime-based quantification. The hyperspectral single-pixel camera implements a DMD (Digital micro-mirror device) to generate optical masks for modulating the illumination field before it is delivered onto the sample and focuses the emission light signals into a multi-anode hyperspectral time-resolved PMT (Photomultiplier tube) to acquire spatial, temporal and spectral information enriched 4-D data sets. Fluorescence dyes with lifetime and spectral contrast are embedded in well plates and thin tissues. L-1 norm based regularization or the least square method, is applied to solve the underdetermined inverse problem during image reconstruction. These experimental results prove the possibility of fast, wide-field mapping of fluorescent labels with lifetime and spectral contrast in thin media.

  20. Sub-pixel mapping of water boundaries using pixel swapping algorithm (case study: Tagliamento River, Italy)

    NASA Astrophysics Data System (ADS)

    Niroumand-Jadidi, Milad; Vitti, Alfonso

    2015-10-01

    Taking the advantages of remotely sensed data for mapping and monitoring of water boundaries is of particular importance in many different management and conservation activities. Imagery data are classified using automatic techniques to produce maps entering the water bodies' analysis chain in several and different points. Very commonly, medium or coarse spatial resolution imagery is used in studies of large water bodies. Data of this kind is affected by the presence of mixed pixels leading to very outstanding problems, in particular when dealing with boundary pixels. A considerable amount of uncertainty inescapably occurs when conventional hard classifiers (e.g., maximum likelihood) are applied on mixed pixels. In this study, Linear Spectral Mixture Model (LSMM) is used to estimate the proportion of water in boundary pixels. Firstly by applying an unsupervised clustering, the water body is identified approximately and a buffer area considered ensuring the selection of entire boundary pixels. Then LSMM is applied on this buffer region to estimate the fractional maps. However, resultant output of LSMM does not provide a sub-pixel map corresponding to water abundances. To tackle with this problem, Pixel Swapping (PS) algorithm is used to allocate sub-pixels within mixed pixels in such a way to maximize the spatial proximity of sub-pixels and pixels in the neighborhood. The water area of two segments of Tagliamento River (Italy) are mapped in sub-pixel resolution (10m) using a 30m Landsat image. To evaluate the proficiency of the proposed approach for sub-pixel boundary mapping, the image is also classified using a conventional hard classifier. A high resolution image of the same area is also classified and used as a reference for accuracy assessment. According to the results, sub-pixel map shows in average about 8 percent higher overall accuracy than hard classification and fits very well in the boundaries with the reference map.

  1. Development of a pixelated GSO gamma camera system with tungsten parallel hole collimator for single photon imaging

    SciTech Connect

    Yamamoto, S.; Watabe, H.; Kanai, Y.; Shimosegawa, E.; Hatazawa, J.

    2012-02-15

    Purpose: In small animal imaging using a single photon emitting radionuclide, a high resolution gamma camera is required. Recently, position sensitive photomultiplier tubes (PSPMTs) with high quantum efficiency have been developed. By combining these with nonhygroscopic scintillators with a relatively low light output, a high resolution gamma camera can become useful for low energy gamma photons. Therefore, the authors developed a gamma camera by combining a pixelated Ce-doped Gd{sub 2}SiO{sub 5} (GSO) block with a high quantum efficiency PSPMT. Methods: GSO was selected for the scintillator, because it is not hygroscopic and does not contain any natural radioactivity. An array of 1.9 mm x 1.9 mm x 7 mm individual GSO crystal elements was constructed. These GSOs were combined with a 0.1-mm thick reflector to form a 22 x 22 matrix and optically coupled to a high quantum efficiency PSPMT (H8500C-100 MOD8). The GSO gamma camera was encased in a tungsten gamma-ray shield with tungsten pixelated parallel hole collimator, and the basic performance was measured for Co-57 gamma photons (122 keV). Results: In a two-dimensional position histogram, all pixels were clearly resolved. The energy resolution was {approx}15% FWHM. With the 20-mm thick tungsten pixelated collimator, the spatial resolution was 4.4-mm FWHM 40 mm from the collimator surface, and the sensitivity was {approx}0.05%. Phantom and small animal images were successfully obtained with our developed gamma camera. Conclusions: These results confirmed that the developed pixelated GSO gamma camera has potential as an effective instrument for low energy gamma photon imaging.

  2. Design of a 12-megapixel imager with a nanowatt A/D converter at each pixel

    NASA Astrophysics Data System (ADS)

    Mandl, William J.

    2003-09-01

    The design for a large format digital visible light area array was developed based on A/D conversion at each pixel. Production CMOS technology was used in the development of a monolithic front side illuminated photo diode pixel. Each pixel includes a one loop MOSAD, multiplexed oversample A/D, converter, the photo diode and a buffered output to support a very large array format operating at a high frame rate. MOSAD is a modification of the delta sigma approach to A/D conversion. The requirements are to develop a 4,000 x 3,000 pixel array capable of up to 1,000 frames per second sample rate. A design was developed using the AMIS 0.35 μm CMOS process with a single poly and three metal layers. To approximately fit a 35 millimeter optics format, a pixel size of 8.5 μm was selected. There are no operational amplifiers required at the pixel to perform the A/D function, thus allowing a high fill factor. With this pixel size, a 48% fill factor and 38% photo diode area was achieved. The design can produce a pixel size of 4.3 μm square with the use of 0.18 μm CMOS without sacrificing fill factor. Alternate approaches to satisfy the 1 kiloframe sample rate with up to 10 bits dynamic range were analyzed. The design is still in progress with layout and simulation of the critical elements complete. This development program is sponsored by the Army White Sands Missile Range.

  3. Reconstruction of color biomedical images by means of quaternion generic Jacobi-Fourier moments in the framework of polar pixels.

    PubMed

    Camacho-Bello, César; Padilla-Vivanco, Alfonso; Toxqui-Quitl, Carina; Báez-Rojas, José Javier

    2016-01-01

    A detailed analysis of the quaternion generic Jacobi-Fourier moments (QGJFMs) for color image description is presented. In order to reach numerical stability, a recursive approach is used during the computation of the generic Jacobi radial polynomials. Moreover, a search criterion is performed to establish the best values for the parameters [Formula: see text] and [Formula: see text] of the radial Jacobi polynomial families. Additionally, a polar pixel approach is taken into account to increase the numerical accuracy in the calculation of the QGJFMs. To prove the mathematical theory, some color images from optical microscopy and human retina are used. Experiments and results about color image reconstruction are presented.

  4. Reconstruction of color biomedical images by means of quaternion generic Jacobi-Fourier moments in the framework of polar pixels

    PubMed Central

    Camacho-Bello, César; Padilla-Vivanco, Alfonso; Toxqui-Quitl, Carina; Báez-Rojas, José Javier

    2016-01-01

    Abstract. A detailed analysis of the quaternion generic Jacobi-Fourier moments (QGJFMs) for color image description is presented. In order to reach numerical stability, a recursive approach is used during the computation of the generic Jacobi radial polynomials. Moreover, a search criterion is performed to establish the best values for the parameters α and β of the radial Jacobi polynomial families. Additionally, a polar pixel approach is taken into account to increase the numerical accuracy in the calculation of the QGJFMs. To prove the mathematical theory, some color images from optical microscopy and human retina are used. Experiments and results about color image reconstruction are presented. PMID:27014716

  5. Development of a new electronic personal neutron dosemeter using a CMOS active pixel sensor.

    PubMed

    Trocmé, M; Higueret, S; Husson, D; Nourreddine, A; Lê, T D

    2007-01-01

    A CMOS active pixel sensor, originally designed for the tracking of minimum ionising charged particles in high-energy physics, has been recently used for the detection of fast neutrons. Data were taken at the IRSN Cadarache facility with a (241)Am-Be ISO source and a polyethylene radiator. A high-intrinsic efficiency (1.2 x 10(-3)) has been obtained. It is in good agreement with both calculations and a MCNPX Monte Carlo simulation. This experiment paves the way for a fully electronic personal neutron dosemeter.

  6. A compact 64-pixel CsI(T1)/Si PIN photodiode imaging module with IC readout

    SciTech Connect

    Gruber, Gregory J.; Choong, Woon-Seng; Moses, William W.; Derenzo, Stephen E.; Holland, Stephen E.; Pedrali-Noy, Marzio; Krieger, Brad; Mandelli, Emanuele; Meddeler, Gerrit; Wang, Nadine W.

    2001-08-09

    We characterize the performance of a complete 64-pixel compact gamma camera imaging module consisting of optically isolated 3 mm 3 mm 5 mm CsI(Tl) crystals coupled to a custom array of low-noise Si PIN photodiodes read out by a custom IC. At 50 V bias the custom 64-pixel photodiode arrays demonstrate an average leakage current of 28 pA per 3 mm 3 mm pixel, a 98.5 percent yield of pixels with <100 pA leakage, and a quantum efficiency of about 80 percent for 540 nm CsI(Tl) scintillation photons. The custom 64-channel readout IC uses low-noise preamplifiers, shaper amplifiers, and a winner-take-all (WTA) multiplexer. The IC demonstrates maximum gain of 120 mV / 1000 e-, the ability to select the largest input signal in less than 150 ns, and low electronic noise at 8 ms peaking time ranging from 25 e- rms (unloaded) to an estimated 180 e- rms (photodiode load of 3 pF, 50 pA). At room temperature a complete 64-pixel detector module employing a custom photodiode array and readout IC demonstrates an average energy resolution of 23.4 percent fwhm and an intrinsic spatial resolution of 3.3 mm fwhm for the 140 keV emissions of 99mTc. Construction of an array of such imaging modules is straightforward, hence this technology shows strong potential for numerous compact gamma camera applications, including scintimammography.

  7. Polarimetric analysis of a CdZnTe spectro-imager under multi-pixel irradiation conditions

    NASA Astrophysics Data System (ADS)

    Pinto, M.; da Silva, R. M. Curado; Maia, J. M.; Simões, N.; Marques, J.; Pereira, L.; Trindade, A. M. F.; Caroli, E.; Auricchio, N.; Stephen, J. B.; Gonçalves, P.

    2016-12-01

    So far, polarimetry in high-energy astrophysics has been insufficiently explored due to the complexity of the required detection, electronic and signal processing systems. However, its importance is today largely recognized by the astrophysical community, therefore the next generation of high-energy space instruments will certainly provide polarimetric observations, contemporaneously with spectroscopy and imaging. We have been participating in high-energy observatory proposals submitted to ESA Cosmic Vision calls, such as GRI (Gamma-Ray Imager), DUAL and ASTROGAM, where the main instrument was a spectro-imager with polarimetric capabilities. More recently, the H2020 AHEAD project was launched with the objective to promote more coherent and mature future high-energy space mission proposals. In this context of high-energy proposal development, we have tested a CdZnTe detection plane prototype polarimeter under a partially polarized gamma-ray beam generated from an aluminum target irradiated by a 22Na (511 keV) radioactive source. The polarized beam cross section was 1 cm2, allowing the irradiation of a wide multi-pixelated area where all the pixels operate simultaneously as a scatterer and as an absorber. The methods implemented to analyze such multi-pixel irradiation are similar to those required to analyze a spectro-imager polarimeter operating in space, since celestial source photons should irradiate its full pixilated area. Correction methods to mitigate systematic errors inherent to CdZnTe and to the experimental conditions were also implemented. The polarization level ( 40%) and the polarization angle (precision of ±5° up to ±9°) obtained under multi-pixel irradiation conditions are presented and compared with simulated data.

  8. Efficient phase contrast imaging in STEM using a pixelated detector. Part 1: Experimental demonstration at atomic resolution

    DOE PAGES

    Pennycook, Timothy J.; Lupini, Andrew R.; Yang, Hao; ...

    2014-10-15

    In this paper, we demonstrate a method to achieve high efficiency phase contrast imaging in aberration corrected scanning transmission electron microscopy (STEM) with a pixelated detector. The pixelated detector is used to record the Ronchigram as a function of probe position which is then analyzed with ptychography. Ptychography has previously been used to provide super-resolution beyond the diffraction limit of the optics, alongside numerically correcting for spherical aberration. Here we rely on a hardware aberration corrector to eliminate aberrations, but use the pixelated detector data set to utilize the largest possible volume of Fourier space to create high efficiency phasemore » contrast images. The use of ptychography to diagnose the effects of chromatic aberration is also demonstrated. In conclusion, the four dimensional dataset is used to compare different bright field detector configurations from the same scan for a sample of bilayer graphene. Our method of high efficiency ptychography produces the clearest images, while annular bright field produces almost no contrast for an in-focus aberration-corrected probe.« less

  9. 32×32 pixel array complementary metal-oxide semiconductor imaging sensor for laser Doppler blood-flow measurement

    NASA Astrophysics Data System (ADS)

    He, Diwei; Kongsavatsak, Chayut; Hayes-Gill, Barrie R.; Crowe, John A.; Morgan, Stephen P.

    2011-05-01

    A 32×32 pixel array has been fabricated in a 0.35-μm complementary metal-oxide semiconductor process with the aim of producing two-dimensional laser Doppler blood-flow images. In the design, each pixel contains five basic elements: a photodiode, a front-end consisting of a current to voltage converter, voltage amplifier, antialiasing filter, and buffer. The analog design is optimized for the detection of laser Doppler blood-flow signals and thus offers advantages over conventional sensors. The analog outputs are passed through an on-chip multiplexer and digitized by an external analog-to-digital converter. The sensor has been fully characterized electrically and optically using modulated electrical and optical signals. A calibration process for fixed pattern noise reduces the standard deviation of the ac gain by a factor of 2. The imaging response is tested by imaging a vibrating test structure and a rotating diffuser. Blood-flow measurements on a finger before and after occlusion demonstrate that the sensor array is capable of detecting blood-flow signals from tissue. The knowledge gained from the characterization of the design can be used to develop a fully integrated laser Doppler blood-flow sensors with a higher number of pixels.

  10. Efficient phase contrast imaging in STEM using a pixelated detector. Part 1: Experimental demonstration at atomic resolution

    SciTech Connect

    Pennycook, Timothy J.; Lupini, Andrew R.; Yang, Hao; Murfitt, Matthew F.; Jones, Lewys; Nellist, Peter D.

    2014-10-15

    In this paper, we demonstrate a method to achieve high efficiency phase contrast imaging in aberration corrected scanning transmission electron microscopy (STEM) with a pixelated detector. The pixelated detector is used to record the Ronchigram as a function of probe position which is then analyzed with ptychography. Ptychography has previously been used to provide super-resolution beyond the diffraction limit of the optics, alongside numerically correcting for spherical aberration. Here we rely on a hardware aberration corrector to eliminate aberrations, but use the pixelated detector data set to utilize the largest possible volume of Fourier space to create high efficiency phase contrast images. The use of ptychography to diagnose the effects of chromatic aberration is also demonstrated. In conclusion, the four dimensional dataset is used to compare different bright field detector configurations from the same scan for a sample of bilayer graphene. Our method of high efficiency ptychography produces the clearest images, while annular bright field produces almost no contrast for an in-focus aberration-corrected probe.

  11. A 65k pixel, 150k frames-per-second camera with global gating and micro-lenses suitable for fluorescence lifetime imaging

    NASA Astrophysics Data System (ADS)

    Burri, Samuel; Powolny, François; Bruschini, Claudio E.; Michalet, Xavier; Regazzoni, Francesco; Charbon, Edoardo

    2014-05-01

    This paper presents our work on a 65k pixel single-photon avalanche diode (SPAD) based imaging sensor realized in a 0.35μm standard CMOS process. At a resolution of 512 by 128 pixels the sensor is read out in 6.4μs to deliver over 150k monochrome frames per second. The individual pixel has a size of 24μm2 and contains the SPAD with a 12T quenching and gating circuitry along with a memory element. The gating signals are distributed across the chip through a balanced tree to minimize the signal skew between the pixels. The array of pixels is row-addressable and data is sent out of the chip on 128 lines in parallel at a frequency of 80MHz. The system is controlled by an FPGA which generates the gating and readout signals and can be used for arbitrary real-time computation on the frames from the sensor. The communication protocol between the camera and a conventional PC is USB2. The active area of the chip is 5% and can be significantly improved with the application of a micro-lens array. A micro-lens array, for use with collimated light, has been designed and its performance is reviewed in the paper. Among other high-speed phenomena the gating circuitry capable of generating illumination periods shorter than 5ns can be used for Fluorescence Lifetime Imaging (FLIM). In order to measure the lifetime of fluorophores excited by a picosecond laser, the sensor's illumination period is synchronized with the excitation laser pulses. A histogram of the photon arrival times relative to the excitation is then constructed by counting the photons arriving during the sensitive time for several positions of the illumination window. The histogram for each pixel is transferred afterwards to a computer where software routines extract the lifetime at each location with an accuracy better than 100ps. We show results for fluorescence lifetime measurements using different fluorophores with lifetimes ranging from 150ps to 5ns.

  12. Improved Design of Active Pixel CMOS Sensors for Charged Particle Detection

    SciTech Connect

    Deptuch, Grzegorz

    2007-11-12

    The Department of Energy (DOE) nuclear physics program requires developments in detector instrumentation electronics with improved energy, position and timing resolution, sensitivity, rate capability, stability, dynamic range, and background suppression. The current Phase-I project was focused on analysis of standard-CMOS photogate Active Pixel Sensors (APS) as an efficient solution to this challenge. The advantages of the CMOS APS over traditional hybrid approaches (i.e., separate detection regions bump-bonded to readout circuits) include greatly reduced cost, low power and the potential for vastly larger pixel counts and densities. However, challenges remain in terms of the signal-to-noise ratio (SNR) and readout speed (currently on the order of milliseconds), which is the major problem for this technology. Recent work has shown that the long readout time for photogate APS is due to the presence of (interface) traps at the semiconductor-oxide interface. This Phase-I work yielded useful results in two areas: (a) Advanced three-dimensional (3D) physics-based simulation models and simulation-based analysis of the impact of interface trap density on the transient charge collection characteristics of existing APS structures; and (b) Preliminary analysis of the feasibility of an improved photogate pixel structure (i.e., new APS design) with an induced electric field under the charge collecting electrode to enhance charge collection. Significant effort was dedicated in Phase-I to the critical task of implementing accurate interface trap models in CFDRC's NanoTCAD 3D semiconductor device-physics simulator. This resulted in validation of the new NanoTCAD models and simulation results against experimental (published) data, within the margin of uncertainty associated with obtaining device geometry, material properties, and experimentation details. Analyses of the new, proposed photogate APS design demonstrated several promising trends.

  13. TFT-Based Active Pixel Sensors for Large Area Thermal Neutron Detection

    NASA Astrophysics Data System (ADS)

    Kunnen, George

    Due to diminishing availability of 3He, which is the critical component of neutron detecting proportional counters, large area flexible arrays are being considered as a potential replacement for neutron detection. A large area flexible array, utilizing semiconductors for both charged particle detection and pixel readout, ensures a large detection surface area in a light weight rugged form. Such a neutron detector could be suitable for deployment at ports of entry. The specific approach used in this research, uses a neutron converter layer which captures incident thermal neutrons, and then emits ionizing charged particles. These ionizing particles cause electron-hole pair generation within a single pixel's integrated sensing diode. The resulting charge is then amplified via a low-noise amplifier. This document begins by discussing the current state of the art in neutron detection and the associated challenges. Then, for the purpose of resolving some of these issues, recent design and modeling efforts towards developing an improved neutron detection system are described. Also presented is a low-noise active pixel sensor (APS) design capable of being implemented in low temperature indium gallium zinc oxide (InGaZnO) or amorphous silicon (a-Si:H) thin film transistor process compatible with plastic substrates. The low gain and limited scalability of this design are improved upon by implementing a new multi-stage self-resetting APS. For each APS design, successful radiation measurements are also presented using PiN diodes for charged particle detection. Next, detection array readout methodologies are modeled and analyzed, and use of a matched filter readout circuit is described as well. Finally, this document discusses detection diode integration with the designed TFT-based APSs.

  14. A novel position and time sensing active pixel sensor with field-assisted electron collection for charged particle tracking and electron microscopy

    NASA Astrophysics Data System (ADS)

    De Geronimo, G.; Deptuch, G.; Dragone, A.; Radeka, V.; Rehak, P.; Castoldi, A.; Fazzi, A.; Gatti, E.; Guazzoni, C.; Rijssenbeek, M.; Dulinski, W.; Besson, A.; Deveaux, M.; Winter, M.

    2006-11-01

    A new type of active pixel sensors (APSs) to track charged particles for particle physics experiments or to count number of electrons that cross any pixel at the focal plane of electron microscopes is described. The electric field of desirable shape is created inside the active volume of the pixel introducing the drift component in the movement of the signal electrons towards charge collecting electrodes. The electric field results from the flow of ˜100 mA/cm 2 hole currents within individual pixels of the sensor. The proposed sensor is produced using a standard industrially available complementary metal oxide silicon (CMOS) process. There are two main advantages of the proposed detectors when compared to the present (February 2005) state-of-the-art, i.e. field-free APS sensors. The first advantage of a field-assisted transport mechanism is the reduction of the charge collection time and of the sharing of the signal electrons between adjacent pixels by diffusion. The second advantage is the freedom to use both kinds of MOS transistors within each pixel of the sensor. Thus, the full functional power of CMOS circuits can be embedded in situ. As an example, 16-bit scalers will be implemented in each pixel of the sensor for electron microscopy. The reduced collection time combined with the state-of-the-art electronics within each pixel provides the most complete information about the position and the timing of incident charged particles for particle physics experiments. Position resolution of new sensors was computationally simulated to be a few microns, that is, the same as the resolution of standard APSs. Moreover, the active depth of the sensor and the associate electronics is less than about 20 μm and a thinned down sensor together with its beryllium backing can have a total thickness of less than 0.1% of one radiation length. The reduction of the thickness of the detector reduces the amount of multiple scattering within the detector. The determination of the

  15. Single-pixel hyperspectral imaging for real-time cancer detection: detecting damage in ex vivo porcine tissue samples

    NASA Astrophysics Data System (ADS)

    Peller, Joseph; Farahi, Faramarz; Trammell, Susan R.

    2016-03-01

    We are developing a single-pixel hyperspectral imaging system based on compressive sensing that acquires spatial and spectral information simultaneously. Our spectral imaging system uses autofluorescencent emission from collagen (400 nm) and NAD(P)H (475 nm), as well as, differences in the optical reflectance spectra as diagnostics for differentiating between healthy and diseased tissue. In this study, we demonstrate the ability of our imaging system to discriminate between healthy and damaged porcine epidermal tissue. Healthy porcine epidermal tissue samples (n=11) were imaged ex vivo using our hyperspectral system. The amount of NAD(P)H emission and the reflectance properties were approximately constant across the surface of healthy tissue samples. The tissue samples were then thermally damaged using an 1850 nm thulium fiber laser and re-imaged after laser irradiation. The damaged regions were clearly visible in the hyperspectral images as the thermal damage altered the fluorescent emission of NAD(P)H and changed the scattering properties of the tissue. The extent of the damaged regions was determined based on the hyperspectral images and these estimates were compared to damage extents measured in white light images acquired with a traditional camera. The extent of damage determined via hyperspectral imaging was in good agreement with estimates based on white light imaging indicating that our system is capable of differentiating between healthy and damaged tissue. Possible applications of our single pixel hyperspectral imaging system range from real-time determination of tumor margins during surgery to the use of this technique in the pathology lab to aid with cancer diagnosis and staging.

  16. Comparison of Several Fusion Paradigms Applied to Pixel-Based Image Classification

    DTIC Science & Technology

    2006-07-01

    Water Data set C Data set D Forest Parking lot 6 bands: TM3, 4 bands: Blue, TM4, TM5, contrast, variance, entropy Green, Red, NIR 1152 x...883 pixels 354 x 263 pixels Resolution: 30 m Resolution: 15 cm 4 classes: Conifers, 3 classes : Cars, Mixed, Deciduous, Military vehicles, Water ...811-823, 1994. [5] D. Dubois and H. Prade, La fusion d’informations imprécises, Traitement du Signal, 11(6):447-458, 1994. [6] A.P. Dempster, A

  17. A neighbor pixel communication filtering structure for Dynamic Vision Sensors

    NASA Astrophysics Data System (ADS)

    Xu, Yuan; Liu, Shiqi; Lu, Hehui; Zhang, Zilong

    2017-02-01

    For Dynamic Vision Sensors (DVS), thermal noise and junction leakage current induced Background Activity (BA) is the major cause of the deterioration of images quality. Inspired by the smoothing filtering principle of horizontal cells in vertebrate retina, A DVS pixel with Neighbor Pixel Communication (NPC) filtering structure is proposed to solve this issue. The NPC structure is designed to judge the validity of pixel's activity through the communication between its 4 adjacent pixels. The pixel's outputs will be suppressed if its activities are determined not real. The proposed pixel's area is 23.76×24.71μm2 and only 3ns output latency is introduced. In order to validate the effectiveness of the structure, a 5×5 pixel array has been implemented in SMIC 0.13μm CIS process. 3 test cases of array's behavioral model show that the NPC-DVS have an ability of filtering the BA.

  18. The effect of atmospheric and topographic correction on pixel-based image composites: Improved forest cover detection in mountain environments

    NASA Astrophysics Data System (ADS)

    Vanonckelen, Steven; Lhermitte, Stef; Van Rompaey, Anton

    2015-03-01

    Quantification of forest cover is essential as a tool to stimulate forest management and conservation. Image compositing techniques that sample the most suited pixel from multi-temporal image acquisitions, provide an important tool for forest cover detection as they provide alternatives for missing data due to cloud cover and data discontinuities. At present, however, it is not clear to which extent forest cover detection based on compositing can be improved if the source imagery is firstly corrected for topographic distortions on a pixel-basis. In this study, the results of a pixel compositing algorithm with and without preprocessing topographic correction are compared for a study area covering 9 Landsat footprints in the Romanian Carpathians based on two different classifiers: Maximum Likelihood (ML) and Support Vector Machine (SVM). Results show that classifier selection has a stronger impact on the classification accuracy than topographic correction. Finally, application of the optimal method (SVM classifier with topographic correction) on the Romanian Carpathian Ecoregion between 1985, 1995 and 2010 shows a steady greening due to more afforestation than deforestation.

  19. Design of ADC in 25 μm pixels pitch dedicated for IRFPA image processing at LETI

    NASA Astrophysics Data System (ADS)

    Tchagaspanian, M.; Villard, P.; Dupont, B.; Chammings, G.; Martin, J. L.; Pistre, C.; Lattard, D.; Chantre, C.; Arnaud, A.; Yon, J. J.; Simoens, F.; Tissot, J. L.

    2007-04-01

    LETI has been involved in IRFPA development since 1978, the design department (LETI/DCIS) has focused its work on new ROIC architecture since many years. The trend is to integrate advanced functions into the CMOS design in the aim of making cost efficient sensors. The purpose of this paper is to present the latest developments of an Analog to Digital Converter embedded in a 25μm pixel. The design is driven by several goals. It targets both long integration time and snapshot exposure, 100% of image frame time being available for integration. All pixels are integrating the IR signal at the same time. The IR signal is converted into digital by using a charge packet counter. High density 130nm CMOS allows to use many digital functions such as counting, memory and addressing. This new structure has been applied to 25μm pitch bolometer sensors with a dedicated 320 x 240 IRCMOS circuit. Due to smart image processing in the CMOS, the bolometer architecture requirements may become very simple and low cost. The room temperature sensitivity and the DC offset are solved directly in the pixel. This FPA targets low NETD (<50mK), a variation of 80 Kelvin for the FPA temperature, 14 bits output at 50/60Hz video rate.

  20. Hard-X and gamma-ray imaging detector for astrophysics based on pixelated CdTe semiconductors

    NASA Astrophysics Data System (ADS)

    Gálvez, J.-L.; Hernanz, M.; Álvarez, L.; Artigues, B.; Ullán, M.; Lozano, M.; Pellegrini, G.; Cabruja, E.; Martínez, R.; Chmeissani, M.; Puigdengoles, C.

    2016-01-01

    Stellar explosions are astrophysical phenomena of great importance and interest. Instruments with high sensitivities are essential to perform detailed studies of cosmic explosions and cosmic accelerators. In order to achieve the needed performance, a hard-X and gamma-ray imaging detector with mm spatial resolution and large enough efficiency is required. We present a detector module which consists of a single CdTe crystal of 12.5 × 12.5mm 2 and 2mm thick with a planar cathode and with the anode segmented in an 11x11 pixel array with a pixel pitch of 1 mm attached to the readout chip. Two possible detector module configurations are considered: the so-called Planar Transverse Field (PTF) and the Parallel Planar Field (PPF). The combination of several modules in PTF or PPF configuration will achieve the desired performance of the imaging detector. The sum energy resolution of all pixels of the CdTe module measured at 122 keV and 356 keV is 3.8% and 2% respectively, in the following operating conditions: PPF irradiation, bias voltage -500 V and temperature -10̂ C.

  1. Direct tests of a pixelated microchannel plate as the active element of a shower maximum detector

    DOE PAGES

    Apresyan, A.; Los, S.; Pena, C.; ...

    2016-05-07

    One possibility to make a fast and radiation resistant shower maximum detector is to use a secondary emitter as an active element. We report our studies of microchannel plate photomultipliers (MCPs) as the active element of a shower-maximum detector. We present test beam results obtained using Photonis XP85011 to detect secondary particles of an electromagnetic shower. We focus on the use of the multiple pixels on the Photonis MCP in order to find a transverse two-dimensional shower distribution. A spatial resolution of 0.8 mm was obtained with an 8 GeV electron beam. As a result, a method for measuring themore » arrival time resolution for electromagnetic showers is presented, and we show that time resolution better than 40 ps can be achieved.« less

  2. Direct tests of a pixelated microchannel plate as the active element of a shower maximum detector

    SciTech Connect

    Apresyan, A.; Los, S.; Pena, C.; Presutti, F.; Ronzhin, A.; Spiropulu, M.; Xie, S.

    2016-05-07

    One possibility to make a fast and radiation resistant shower maximum detector is to use a secondary emitter as an active element. We report our studies of microchannel plate photomultipliers (MCPs) as the active element of a shower-maximum detector. We present test beam results obtained using Photonis XP85011 to detect secondary particles of an electromagnetic shower. We focus on the use of the multiple pixels on the Photonis MCP in order to find a transverse two-dimensional shower distribution. A spatial resolution of 0.8 mm was obtained with an 8 GeV electron beam. As a result, a method for measuring the arrival time resolution for electromagnetic showers is presented, and we show that time resolution better than 40 ps can be achieved.

  3. K-edge imaging with the XPAD3 hybrid pixel detector, direct comparison of CdTe and Si sensors.

    PubMed

    Cassol, F; Portal, L; Graber-Bolis, J; Perez-Ponce, H; Dupont, M; Kronland, C; Boursier, Y; Blanc, N; Bompard, F; Boudet, N; Buton, C; Clémens, J C; Dawiec, A; Debarbieux, F; Delpierre, P; Hustache, S; Vigeolas, E; Morel, C

    2015-07-21

    We investigate the improvement from the use of high-Z CdTe sensors for pre-clinical K-edge imaging with the hybrid pixel detectors XPAD3. We compare XPAD3 chips bump bonded to Si or CdTe sensors in identical experimental conditions. Image performance for narrow energy bin acquisitions and contrast-to-noise ratios of K-edge images are presented and compared. CdTe sensors achieve signal-to-noise ratios at least three times higher than Si sensors within narrow energy bins, thanks to their much higher detection efficiency. Nevertheless Si sensors provide better contrast-to-noise ratios in K-edge imaging when working at equivalent counting statistics, due to their better estimation of the attenuation coefficient of the contrast agent. Results are compared to simulated data in the case of the XPAD3/Si detector. Good agreement is observed when including charge sharing between pixels, which have a strong impact on contrast-to-noise ratios in K-edge images.

  4. Early breast tumor and late SARS detections using space-variant multispectral infrared imaging at a single pixel

    NASA Astrophysics Data System (ADS)

    Szu, Harold H.; Buss, James R.; Kopriva, Ivica

    2004-04-01

    We proposed the physics approach to solve a physical inverse problem, namely to choose the unique equilibrium solution (at the minimum free energy: H= E - ToS, including the Wiener, l.m.s E, and ICA, Max S, as special cases). The "unsupervised classification" presumes that required information must be learned and derived directly and solely from the data alone, in consistence with the classical Duda-Hart ATR definition of the "unlabelled data". Such truly unsupervised methodology is presented for space-variant imaging processing for a single pixel in the real world case of remote sensing, early tumor detections and SARS. The indeterminacy of the multiple solutions of the inverse problem is regulated or selected by means of the absolute minimum of isothermal free energy as the ground truth of local equilibrium condition at the single-pixel foot print.

  5. Introduction to the GEOBIA 2010 special issue: From pixels to geographic objects in remote sensing image analysis

    NASA Astrophysics Data System (ADS)

    Addink, Elisabeth A.; Van Coillie, Frieke M. B.; De Jong, Steven M.

    2012-04-01

    Traditional image analysis methods are mostly pixel-based and use the spectral differences of landscape elements at the Earth surface to classify these elements or to extract element properties from the Earth Observation image. Geographic object-based image analysis (GEOBIA) has received considerable attention over the past 15 years for analyzing and interpreting remote sensing imagery. In contrast to traditional image analysis, GEOBIA works more like the human eye-brain combination does. The latter uses the object's color (spectral information), size, texture, shape and occurrence to other image objects to interpret and analyze what we see. GEOBIA starts by segmenting the image grouping together pixels into objects and next uses a wide range of object properties to classify the objects or to extract object's properties from the image. Significant advances and improvements in image analysis and interpretation are made thanks to GEOBIA. In June 2010 the third conference on GEOBIA took place at the Ghent University after successful previous meetings in Calgary (2008) and Salzburg (2006). This special issue presents a selection of the 2010 conference papers that are worked out as full research papers for JAG. The papers cover GEOBIA applications as well as innovative methods and techniques. The topics range from vegetation mapping, forest parameter estimation, tree crown identification, urban mapping, land cover change, feature selection methods and the effects of image compression on segmentation. From the original 94 conference papers, 26 full research manuscripts were submitted; nine papers were selected and are presented in this special issue. Selection was done on the basis of quality and topic of the studies. The next GEOBIA conference will take place in Rio de Janeiro from 7 to 9 May 2012 where we hope to welcome even more scientists working in the field of GEOBIA.

  6. Radarclinometry: Bootstrapping the radar reflectance function from the image pixel-signal frequency distribution and an altimetry profile

    USGS Publications Warehouse

    Wildey, R.L.

    1988-01-01

    A method is derived for determining the dependence of radar backscatter on incidence angle that is applicable to the region corresponding to a particular radar image. The method is based on enforcing mathematical consistency between the frequency distribution of the image's pixel signals (histogram of DN values with suitable normalizations) and a one-dimensional frequency distribution of slope component, as might be obtained from a radar or laser altimetry profile in or near the area imaged. In order to achieve a unique solution, the auxiliary assumption is made that the two-dimensional frequency distribution of slope is isotropic. The backscatter is not derived in absolute units. The method is developed in such a way as to separate the reflectance function from the pixel-signal transfer characteristic. However, these two sources of variation are distinguishable only on the basis of a weak dependence on the azimuthal component of slope; therefore such an approach can be expected to be ill-conditioned unless the revision of the transfer characteristic is limited to the determination of an additive instrumental background level. The altimetry profile does not have to be registered in the image, and the statistical nature of the approach minimizes pixel noise effects and the effects of a disparity between the resolutions of the image and the altimetry profile, except in the wings of the distribution where low-number statistics preclude accuracy anyway. The problem of dealing with unknown slope components perpendicular to the profiling traverse, which besets the one-to-one comparison between individual slope components and pixel-signal values, disappears in the present approach. In order to test the resulting algorithm, an artificial radar image was generated from the digitized topographic map of the Lake Champlain West quadrangle in the Adirondack Mountains, U.S.A., using an arbitrarily selected reflectance function. From the same map, a one-dimensional frequency

  7. Sub-pixel correlation length neutron imaging: Spatially resolved scattering information of microstructures on a macroscopic scale

    NASA Astrophysics Data System (ADS)

    Harti, Ralph P.; Strobl, Markus; Betz, Benedikt; Jefimovs, Konstantins; Kagias, Matias; Grünzweig, Christian

    2017-03-01

    Neutron imaging and scattering give data of significantly different nature and traditional methods leave a gap of accessible structure sizes at around 10 micrometers. Only in recent years overlap in the probed size ranges could be achieved by independent application of high resolution scattering and imaging methods, however without providing full structural information when microstructures vary on a macroscopic scale. In this study we show how quantitative neutron dark-field imaging with a novel experimental approach provides both sub-pixel resolution with respect to microscopic correlation lengths and imaging of macroscopic variations of the microstructure. Thus it provides combined information on multiple length scales. A dispersion of micrometer sized polystyrene colloids was chosen as a model system to study gravity induced crystallisation of microspheres on a macro scale, including the identification of ordered as well as unordered phases. Our results pave the way to study heterogeneous systems locally in a previously impossible manner.

  8. Sub-pixel correlation length neutron imaging: Spatially resolved scattering information of microstructures on a macroscopic scale

    PubMed Central

    Harti, Ralph P.; Strobl, Markus; Betz, Benedikt; Jefimovs, Konstantins; Kagias, Matias; Grünzweig, Christian

    2017-01-01

    Neutron imaging and scattering give data of significantly different nature and traditional methods leave a gap of accessible structure sizes at around 10 micrometers. Only in recent years overlap in the probed size ranges could be achieved by independent application of high resolution scattering and imaging methods, however without providing full structural information when microstructures vary on a macroscopic scale. In this study we show how quantitative neutron dark-field imaging with a novel experimental approach provides both sub-pixel resolution with respect to microscopic correlation lengths and imaging of macroscopic variations of the microstructure. Thus it provides combined information on multiple length scales. A dispersion of micrometer sized polystyrene colloids was chosen as a model system to study gravity induced crystallisation of microspheres on a macro scale, including the identification of ordered as well as unordered phases. Our results pave the way to study heterogeneous systems locally in a previously impossible manner. PMID:28303923

  9. Radarclinometry - Bootstrapping the radar reflectance function from the image pixel-signal frequency distribution and an altimetry profile

    NASA Technical Reports Server (NTRS)

    Wildey, Robert L.

    1988-01-01

    A method for determining the dependence of radar backscatter on incidence angle that is applicable to the region corresponding to a particular radar image is derived. The method is based on enforcing mathematical consistency between the frequency distribution of the images' pixel signals and a one-dimensional frequency distribution of slope component, which is obtained from a radar or laser altimetry profile in or near the imaged area. To test the resulting algorithm, an arbitrarily selected reflectance function is used to generate an artificial radar image from a digitized topographic map of the Lake Champlain West quadrangle in the Adirondack Mountains, U.S. It is found that, for 99 percent of the data, the maximum error is 1 degree.

  10. Smart-pixel for 3D ranging imagers based on single-photon avalanche diode and time-to-digital converter

    NASA Astrophysics Data System (ADS)

    Markovic, Bojan; Tisa, Simone; Tosi, Alberto; Zappa, Franco

    2011-05-01

    We present a "smart-pixel" suitable for implementation of monolithic single-photon imaging arrays aimed at 3D ranging applications by means of the direct time-of-flight detection (like LIDAR systems), but also for photon timing applications (like FLIM, FCS, FRET). The pixel includes a Single-Photon Avalanche Diode (SPAD) and a Time-to-Digital Converter (TDC) monolithically designed and manufactured in the same chip, and it is able to detect single photons and to measure in-pixel the time delay between a START signal (e.g. laser excitation, LIDAR flash) and a photon detection (e.g. back reflection from a target object). In order to provide both wide dynamic range, high time resolution and very high linearity, we devised a TDC architecture based on an interpolation technique. A "coarse" counter counts the number of reference-clock rising-edges between START and STOP, while high resolution is achieved by means of two interpolators, which measure the time elapsed between START (and STOP) signal and a successive clock edge. In an array with many pixels, multiple STOP channels are needed while just one START channel is necessary if the START event is common to all channels. We report on the design and characterization of prototype circuits, fabricated in a 0.35 μm standard CMOS technology containing complete conversion channels (i.e. 20-μm active-area diameter SPAD, quenching circuitry, and TDC). With a 100 MHz reference clock, the TDC provides a time resolution of 10 ps, a dynamic range of 160 ns and DNL < 1% LSB rms.

  11. A radiation-hardened two transistor memory cell for monolithic active pixel sensors in STAR experiment

    NASA Astrophysics Data System (ADS)

    Wei, X.; Gao, D.; Dorokhov, A.; Hu, Y.

    2011-01-01

    Radiation tolerance of Monolithic Active Pixel Sensors (MAPS) is dramatically decreased when intellectual property (IP) memories are integrated for fast readout application. This paper presents a new solution to improve radiation hardness and avoid latch-up for memory cell design. The tradeoffs among radiation tolerance, area and speed are significantly considered and analyzed. The cell designed in 0.35 μm process satisfies the radiation tolerance requirements of STAR experiment. The cell size is 4.55 × 5.45 μm2. This cell is smaller than the IP memory cell based on the same process and is only 26% of a radiation tolerant 6T SRAM cell used in previous contribution. The write access time of the cell is less than 2 ns, while the read access time is 80 ns.

  12. Impact of Substrate Bias on Fixed-Pattern-Noise in Active Pixel Sensor Cells

    NASA Astrophysics Data System (ADS)

    Terauchi, Mamoru

    2007-11-01

    The effect of substrate (body) bias on fixed-pattern-noise (FPN) in active pixel sensor (APS) cells is studied. Through measuring test devices consisting of two metal-oxide-semiconductor field-effect transistors (MOSFETs) connected in series with each of the transistors located in the same well region, it has been revealed that substrate bias, which is inevitably applied in a normal circuit configuration in conventional APS cells, worsens the characteristics fluctuation in source-follower amplifiers in APS cells, leading to FPN that cannot be mitigated by conventional correction methods such as correlated double sampling. In addition it has been confirmed that the current-voltage characteristics of logarithmic converters, each of which is realized using a MOSFET with gate and drain terminals connected together, are also affected by substrate bias, resulting in increased characteristics fluctuation as compared with the case with no substrate bias.

  13. First measurement of the in-pixel electron multiplying with a standard imaging CMOS technology: Study of the EMCMOS concept

    NASA Astrophysics Data System (ADS)

    Brugière, Timothée; Mayer, Fréderic; Fereyre, Pierre; Guérin, Cyrille; Dominjon, Agnés; Barbier, Rémi

    2015-07-01

    Scientific low light imaging devices benefit today from designs for pushing the mean noise to the single electron level. When readout noise reduction reaches its limit, signal-to-noise ratio improvement can be driven by an electron multiplication process, driven by impact ionization, before adding the readout noises. This concept already implemented in CCD structures using extra-pixel shift registers can today be integrated inside each pixel in CMOS technology. The EBCMOS group at IPNL is in charge of the characterization of new prototypes developed by E2V using this concept: the electron multiplying CMOS (EMCMOS). The CMOS technology enables electron multiplication inside the photodiode itself, and thus, an overlap of the charge integration and multiplication. A new modeling has been developed to describe the output signal mean and variance after the impact ionization process in such a case. In this paper the feasibility of impact ionization process inside a 8 μm-pitch pixel is demonstrated. The new modeling is also validated by data and a value of 0.32% is obtained for the impact ionization parameter α with an electric field intensity of 24 V / μm.

  14. A quantum efficiency analytical model for complementary metal—oxide—semiconductor image pixels with a pinned photodiode structure

    NASA Astrophysics Data System (ADS)

    Cao, Chen; Zhang, Bing; Wu, Long-Sheng; Li, Na; Wang, Jun-Feng

    2014-12-01

    A quantum efficiency analytical model for complementary metal—oxide—semiconductor (CMOS) image pixels with a pinned photodiode structure is developed. The proposed model takes account of the non-uniform doping distribution in the N-type region due to the impurity compensation formed by the actual fabricating process. The characteristics of two boundary PN junctions located in the N-type region for the particular spectral response of a pinned photodiode, are quantitatively analyzed. By solving the minority carrier steady-state diffusion equations and the barrier region photocurrent density equations successively, the analytical relationship between the quantum efficiency and the corresponding parameters such as incident wavelength, N-type width, peak doping concentration, and impurity density gradient of the N-type region is established. The validity of the model is verified by the measurement results with a test chip of 160 × 160 pixels array, which provides the accurate process with a theoretical guidance for quantum efficiency design in pinned photodiode pixels.

  15. Migrating from superconducting to semiconducting YBCO thin film bolometers as future far-infrared imaging pixels

    NASA Astrophysics Data System (ADS)

    Jagtap, Vishal S.; Longhin, Mattia; Kulsreshath, Mukesh K.; Kreisler, Alain J.; Dégardin, Annick F.

    2010-04-01

    YBa2Cu3O6+x compounds are well known to exhibit superconducting properties for x > 0.5 and semiconducting properties for lower oxygen content. Superconducting YBCO was obtained commercially; the semiconducting material was deposited by sputtering at room temperature. In order to migrate from superconducting to uncooled semiconducting far-infrared bolometer technologies, we have first realized and compared the performance of 2 × 2 pixel arrays made from both materials deposited on MgO substrates. Pixels were in the shape of meanders, embedded in an area of about 1 mm2. Pixel detectivity and thermal crosstalk were studied in the 1 Hz to 100 kHz modulation frequency range by using a 850 nm solid state laser. Secondly we have improved the geometry of semiconducting YBCO bolometers fabricated on silicon substrates, in order to match their impedance with the impedance of the antenna required for working in the THz range. First optical results are also presented, where both regular bolometric and pyroelectric responses are exhibited.

  16. An Efficient Approach for Pixel Decomposition to Increase the Spatial Resolution of Land Surface Temperature Images from MODIS Thermal Infrared Band Data

    PubMed Central

    Wang, Fei; Qin, Zhihao; Li, Wenjuan; Song, Caiying; Karnieli, Arnon; Zhao, Shuhe

    2015-01-01

    Land surface temperature (LST) images retrieved from the thermal infrared (TIR) band data of Moderate Resolution Imaging Spectroradiometer (MODIS) have much lower spatial resolution than the MODIS visible and near-infrared (VNIR) band data. The coarse pixel scale of MODIS LST images (1000 m under nadir) have limited their capability in applying to many studies required high spatial resolution in comparison of the MODIS VNIR band data with pixel scale of 250–500 m. In this paper we intend to develop an efficient approach for pixel decomposition to increase the spatial resolution of MODIS LST image using the VNIR band data as assistance. The unique feature of this approach is to maintain the thermal radiance of parent pixels in the MODIS LST image unchanged after they are decomposed into the sub-pixels in the resulted image. There are two important steps in the decomposition: initial temperature estimation and final temperature determination. Therefore the approach can be termed double-step pixel decomposition (DSPD). Both steps involve a series of procedures to achieve the final result of decomposed LST image, including classification of the surface patterns, establishment of LST change with normalized difference of vegetation index (NDVI) and building index (NDBI), reversion of LST into thermal radiance through Planck equation, and computation of weights for the sub-pixels of the resulted image. Since the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) with much higher spatial resolution than MODIS data was on-board the same platform (Terra) as MODIS for Earth observation, an experiment had been done in the study to validate the accuracy and efficiency of our approach for pixel decomposition. The ASTER LST image was used as the reference to compare with the decomposed LST image. The result showed that the spatial distribution of the decomposed LST image was very similar to that of the ASTER LST image with a root mean square error (RMSE) of

  17. Calibrating the pixel-level Kepler imaging data with a causal data-driven model

    NASA Astrophysics Data System (ADS)

    Wang, Dun; Foreman-Mackey, Daniel; Hogg, David W.; Schölkopf, Bernhard

    2015-01-01

    In general, astronomical observations are affected by several kinds of noise, each with it's own causal source; there is photon noise, stochastic source variability, and residuals coming from imperfect calibration of the detector or telescope. In particular, the precision of NASA Kepler photometry for exoplanet science—the most precise photometric measurements of stars ever made—appears to be limited by unknown or untracked variations in spacecraft pointing and temperature, and unmodeled stellar variability. Here we present the Causal Pixel Model (CPM) for Kepler data, a data-driven model intended to capture variability but preserve transit signals. The CPM works at the pixel level (not the photometric measurement level); it can capture more fine-grained information about the variation of the spacecraft than is available in the pixel-summed aperture photometry. The basic idea is that CPM predicts each target pixel value from a large number of pixels of other stars sharing the instrument variabilities while not containing any information on possible transits at the target star. In addition, we use the target star's future and past (auto-regression). By appropriately separating the data into training and test sets, we ensure that information about any transit will be perfectly isolated from the fitting of the model. The method has four hyper-parameters (the number of predictor stars, the auto-regressive window size, and two L2-regularization amplitudes for model components), which we set by cross-validation. We determine a generic set of hyper-parameters that works well on most of the stars with 11≤V≤12 mag and apply the method to a corresponding set of target stars with known planet transits. We find that we can consistently outperform (for the purposes of exoplanet detection) the Kepler Pre-search Data Conditioning (PDC) method for exoplanet discovery, often improving the SNR by a factor of two. While we have not yet exhaustively tested the method at other

  18. Non-rigid contour-to-pixel registration of photographic and quantitative light-induced fluorescence imaging of decalcified teeth

    NASA Astrophysics Data System (ADS)

    Berkels, Benjamin; Deserno, Thomas; Ehrlich, Eva E.; Fritz, Ulrike B.; Sirazitdinova, Ekaterina; Tatano, Rosalia

    2016-03-01

    Quantitative light-induced fluorescence (QLF) is widely used to assess the damage of a tooth due to decalcification. In digital photographs, decalcification appears as white spot lesions, i.e. white spots on the tooth surface. We propose a novel multimodal registration approach for the matching of digital photographs and QLF images of decalcified teeth. The registration is based on the idea of contour-to-pixel matching. Here, the curve, which represents the shape of the tooth, is extracted from the QLF image using a contour segmentation by binarization and morphological processing. This curve is aligned to the photo with a non-rigid variational registration approach. Thus, the registration problem is formulated as minimization problem with an objective function that consists of a data term and a regularizer for the deformation. To construct the data term, the photo is pointwise classified into tooth and non-tooth regions. Then, the signed distance function of the tooth region allows to measure the mismatch between curve and photo. As regularizer a higher order, linear elastic prior is used. The resulting minimization problem is solved numerically using bilinear Finite Elements for the spatial discretization and the Gauss-Newton algorithm. The evaluation is based on 150 image pairs, where an average of 5 teeth have been captured from 32 subjects. All registrations have been confirmed correctly by a dental expert. The contour-to-pixel methods can directly be used in 3D for surface-to-voxel tasks.

  19. Resampling Images to a Regular Grid From a Non-Regular Subset of Pixel Positions Using Frequency Selective Reconstruction.

    PubMed

    Seiler, Jurgen; Jonscher, Markus; Schöberl, Michael; Kaup, André

    2015-11-01

    Even though image signals are typically defined on a regular 2D grid, there also exist many scenarios where this is not the case and the amplitude of the image signal only is available for a non-regular subset of pixel positions. In such a case, a resampling of the image to a regular grid has to be carried out. This is necessary since almost all algorithms and technologies for processing, transmitting or displaying image signals rely on the samples being available on a regular grid. Thus, it is of great importance to reconstruct the image on this regular grid, so that the reconstruction comes closest to the case that the signal has been originally acquired on the regular grid. In this paper, Frequency Selective Reconstruction is introduced for solving this challenging task. This algorithm reconstructs image signals by exploiting the property that small areas of images can be represented sparsely in the Fourier domain. By further considering the basic properties of the optical transfer function of imaging systems, a sparse model of the signal is iteratively generated. In doing so, the proposed algorithm is able to achieve a very high reconstruction quality, in terms of peak signal-to-noise ratio (PSNR) and structural similarity measure as well as in terms of visual quality. The simulation results show that the proposed algorithm is able to outperform state-of-the-art reconstruction algorithms and gains of more than 1 dB PSNR are possible.

  20. A Low-Noise CMOS THz Imager Based on Source Modulation and an In-Pixel High-Q Passive Switched-Capacitor N-Path Filter.

    PubMed

    Boukhayma, Assim; Dupret, Antoine; Rostaing, Jean-Pierre; Enz, Christian

    2016-03-03

    This paper presents the first low noise complementary metal oxide semiconductor (CMOS) deletedCMOS terahertz (THz) imager based on source modulation and in-pixel high-Q filtering. The 31 × 31 focal plane array has been fully integrated in a 0 . 13 μ m standard CMOS process. The sensitivity has been improved significantly by modulating the active THz source that lights the scene and performing on-chip high-Q filtering. Each pixel encompass a broadband bow tie antenna coupled to an N-type metal-oxide-semiconductor (NMOS) detector that shifts the THz radiation, a low noise adjustable gain amplifier and a high-Q filter centered at the modulation frequency. The filter is based on a passive switched-capacitor (SC) N-path filter combined with a continuous-time broad-band Gm-C filter. A simplified analysis that helps in designing and tuning the passive SC N-path filter is provided. The characterization of the readout chain shows that a Q factor of 100 has been achieved for the filter with a good matching between the analytical calculation and the measurement results. An input-referred noise of 0 . 2 μ V RMS has been measured. Characterization of the chip with different THz wavelengths confirms the broadband feature of the antenna and shows that this THz imager reaches a total noise equivalent power of 0 . 6 nW at 270 GHz and 0 . 8 nW at 600 GHz.

  1. The development and performance of UV-enhanced APD-arrays for high resolution PET imaging coupled with pixelized Pr:LuAG crystal

    NASA Astrophysics Data System (ADS)

    Yoshino, M.; Kataoka, J.; Nakamori, T.; Matsuda, H.; Miura, T.; Katou, T.; Ishikawa, Y.; Kawabata, N.; Matsunaga, Y.; Kamada, K.; Usuki, Y.; Yoshikawa, A.; Yanagida, T.

    2011-07-01

    The development of high-resolution, UV-enhanced avalanche photodiode (APD) arrays usable in high-resolution PET imaging is underway. These APD arrays were specifically designed as photosensors capable of direct coupling with pixelized Pr-doped Lu 3Al 5O 12 (Pr:LuAG) scintillators. An excellent quantum efficiency (QE) of 55% was achieved at the peak emission of Pr:LuAG (310 nm), namely, a substantial improvement from the QE ≤5% as measured with the conventional Hamamatsu reverse-type APDs (S8664 series). Each APD device has 8×8 (TYP1) and 12×12 (TYP2) pixel structures with active areas of 3×3 mm 2 and 2×2 mm 2 in each pixel, respectively. A gain uniformity of ±8% and low dark noise of ≤2 nA/pixel have been achieved, measured at +25 °C. We also report on the large size single crystal growth of improved Pr:LuAG scintillators and the preliminary performance test of the same. An energy resolution of 4.2% (FWHM) was obtained for 662 keV gamma-rays for 10×10×10 mm 3 crystal, measured with a PMT employing a super-bialkali photocathode. We made a test module consisting of a UV-enhanced APD-array (either TYP1 or TYP2) optically coupled with an 8×8 (or 12×12) pixel Pr:LuAG matrix. The linearity between the output signals and incident gamma-ray energy of TYP1 and TYP2 gamma-ray detectors were only 0.27 and 0.33%, as measured at +25 °C for various gamma-ray sources, respectively. Energy resolutions of 7.0±0.2% (FWHM) and 9.0±0.6% (FWHM) were, respectively, obtained for TYP1 and TYP2 detector arrays for 662 keV gamma-rays. The uniformity of the pulse height distributions was also measured at less than 8% for both detectors. Finally, we measured the coincidence timing resolution of these gamma-ray detectors and obtained 4.0±0.1 ns (FWHM) for the 511 keV annihilation quanta from a 22Na source. These results suggest that UV-enhanced APD-arrays coupled with Pr:LuAG scintillators could be a promising device for future application in nuclear medicine.

  2. A Monolithic Active Pixel Sensor for ionizing radiation using a 180 nm HV-SOI process

    NASA Astrophysics Data System (ADS)

    Hemperek, Tomasz; Kishishita, Tetsuichi; Krüger, Hans; Wermes, Norbert

    2015-10-01

    An improved SOI-MAPS (Silicon On Insulator Monolithic Active Pixel Sensor) for ionizing radiation based on thick-film High Voltage SOI technology (HV-SOI) has been developed. Similar to existing Fully Depleted SOI-based (FD-SOI) MAPS, a buried silicon oxide inter-dielectric (BOX) layer is used to separate the CMOS electronics from the handle wafer which is used as a depleted charge collection layer. FD-SOI MAPS suffers from radiation damage such as transistor threshold voltage shifts due to charge traps in the oxide layers and charge states created at the silicon oxide boundaries (back gate effect). The X-FAB 180-nm HV-SOI technology offers an additional isolation by deep non-depleted implant between the BOX layer and the active circuitry which mitigates this problem. Therefore we see in this technology a high potential to implement radiation-tolerant MAPS with fast charge collection property. The design and measurement results from a first prototype are presented including charge collection in neutron irradiated samples.

  3. Breast ultrasound image segmentation: an optimization approach based on super-pixels and high-level descriptors

    NASA Astrophysics Data System (ADS)

    Massich, Joan; Lemaître, Guillaume; Martí, Joan; Mériaudeau, Fabrice

    2015-04-01

    Breast cancer is the second most common cancer and the leading cause of cancer death among women. Medical imaging has become an indispensable tool for its diagnosis and follow up. During the last decade, the medical community has promoted to incorporate Ultra-Sound (US) screening as part of the standard routine. The main reason for using US imaging is its capability to differentiate benign from malignant masses, when compared to other imaging techniques. The increasing usage of US imaging encourages the development of Computer Aided Diagnosis (CAD) systems applied to Breast Ultra-Sound (BUS) images. However accurate delineations of the lesions and structures of the breast are essential for CAD systems in order to extract information needed to perform diagnosis. This article proposes a highly modular and flexible framework for segmenting lesions and tissues present in BUS images. The proposal takes advantage of optimization strategies using super-pixels and high-level descriptors, which are analogous to the visual cues used by radiologists. Qualitative and quantitative results are provided stating a performance within the range of the state-of-the-art.

  4. Enhancing spatial resolution of (18)F positron imaging with the Timepix detector by classification of primary fired pixels using support vector machine.

    PubMed

    Wang, Qian; Liu, Zhen; Ziegler, Sibylle I; Shi, Kuangyu

    2015-07-07

    Position-sensitive positron cameras using silicon pixel detectors have been applied for some preclinical and intraoperative clinical applications. However, the spatial resolution of a positron camera is limited by positron multiple scattering in the detector. An incident positron may fire a number of successive pixels on the imaging plane. It is still impossible to capture the primary fired pixel along a particle trajectory by hardware or to perceive the pixel firing sequence by direct observation. Here, we propose a novel data-driven method to improve the spatial resolution by classifying the primary pixels within the detector using support vector machine. A classification model is constructed by learning the features of positron trajectories based on Monte-Carlo simulations using Geant4. Topological and energy features of pixels fired by (18)F positrons were considered for the training and classification. After applying the classification model on measurements, the primary fired pixels of the positron tracks in the silicon detector were estimated. The method was tested and assessed for [(18)F]FDG imaging of an absorbing edge protocol and a leaf sample. The proposed method improved the spatial resolution from 154.6   ±   4.2 µm (energy weighted centroid approximation) to 132.3   ±   3.5 µm in the absorbing edge measurements. For the positron imaging of a leaf sample, the proposed method achieved lower root mean square error relative to phosphor plate imaging, and higher similarity with the reference optical image. The improvements of the preliminary results support further investigation of the proposed algorithm for the enhancement of positron imaging in clinical and preclinical applications.

  5. An enhanced neighborhood similar pixel interpolator approach for removing thick clouds in landsat images

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Thick cloud contaminations in Landsat images limit their regular usage for land applications. A few methods have been developed to remove thick clouds using additional cloud-free images. Unfortunately, the cloud-free composition image produced by existing methods commonly lacks from the desired spat...

  6. Characterization of high resolution CMOS monolithic active pixel detector in SOI technology

    NASA Astrophysics Data System (ADS)

    Ahmed, M. I.; Arai, Y.; Glab, S.; Idzik, M.; Kapusta, P.; Miyoshi, T.; Takeda, A.; Turala, M.

    2015-05-01

    Novel CMOS monolithic pixel detectors designed at KEK and fabricated at Lapis Semiconductor in 0.2 μm Silicon-on-Insulator (SOI) technology are presented. A thin layer of silicon oxide separates high and low resistivity silicon layers, allowing for optimization of design of detector and readout parts. Shallow wells buried under the oxide in the detector part screen the entire pixel electronics from electrical field applied to the detector. Several integration type SOI pixel detectors have been developed with pixel sizes 8-20 μm. The general features of 14 × 14 μm2 detectors designed on different wafers (CZ-n, FZ-n and FZ-p) were measured and compared. The detector performance was studied under irradiation with visible and infra-red laser, and also X-ray ionizing source. Using X-rays from an Am-241 source the noise of readout electronics was measured at different working conditions, showing the ENC in the range of 88-120 e-. The pixel current was calculated from average DC pedestal shift while varying the pixel integration time. The operation of the detector was studied under partial and full depletion conditions. The effects of temperature and detector bias voltage on noise and leakage current were studied. Characteristics of an ADC integrated in the front-end chip are also presented.

  7. Outcomes-Based CV Imaging Research Endpoints and Trial Design: From Pixels to Patient Satisfaction.

    PubMed

    Fordyce, Christopher B; Douglas, Pamela S

    2017-03-01

    The categories and quality of evidence documenting the value of noninvasive cardiovascular imaging have evolved substantially over the last several decades. From an initial emphasis on the diagnostic accuracy of various imaging modalities, cardiovascular imaging has matured into an outcomes-based field that now provides evidence on adverse events, safety, cost, and patient quality-of-life endpoints, and does so in the setting of large randomized trials. This review aims to highlight types of outcomes endpoints, including updating the hierarchy of evidence for diagnostic imaging as first proposed by Fryback and Thornbury, and critically reviewing their application in the current cardiovascular imaging evidence base. We describe the range of data categories generated to date for the various imaging modalities, and indicate how this provides insights into contemporary study design and future directions in cardiovascular imaging outcomes research.

  8. A novel CMOS sensor with in-pixel auto-zeroed discrimination for charged particle tracking

    NASA Astrophysics Data System (ADS)

    Degerli, Y.; Guilloux, F.; Orsini, F.

    2014-05-01

    With the aim of developing fast and granular Monolithic Active Pixels Sensors (MAPS) as new charged particle tracking detectors for high energy physics experiments, a new rolling shutter binary pixel architecture concept (RSBPix) with in-pixel correlated double sampling, amplification and discrimination is presented. The discriminator features auto-zeroing in order to compensate process-related transistor mismatches. In order to validate the pixel, a first monolithic CMOS sensor prototype, including a pixel array of 96 × 64 pixels, has been designed and fabricated in the Tower-Jazz 0.18 μm CMOS Image Sensor (CIS) process. Results of laboratory tests are presented.

  9. Compact VLSI neural computer integrated with active pixel sensor for real-time ATR applications

    NASA Astrophysics Data System (ADS)

    Fang, Wai-Chi; Udomkesmalee, Gabriel; Alkalai, Leon

    1997-04-01

    A compact VLSI neural computer integrated with an active pixel sensor has been under development to mimic what is inherent in biological vision systems. This electronic eye- brain computer is targeted for real-time machine vision applications which require both high-bandwidth communication and high-performance computing for data sensing, synergy of multiple types of sensory information, feature extraction, target detection, target recognition, and control functions. The neural computer is based on a composite structure which combines Annealing Cellular Neural Network (ACNN) and Hierarchical Self-Organization Neural Network (HSONN). The ACNN architecture is a programmable and scalable multi- dimensional array of annealing neurons which are locally connected with their local neurons. Meanwhile, the HSONN adopts a hierarchical structure with nonlinear basis functions. The ACNN+HSONN neural computer is effectively designed to perform programmable functions for machine vision processing in all levels with its embedded host processor. It provides a two order-of-magnitude increase in computation power over the state-of-the-art microcomputer and DSP microelectronics. A compact current-mode VLSI design feasibility of the ACNN+HSONN neural computer is demonstrated by a 3D 16X8X9-cube neural processor chip design in a 2-micrometers CMOS technology. Integration of this neural computer as one slice of a 4'X4' multichip module into the 3D MCM based avionics architecture for NASA's New Millennium Program is also described.

  10. A 1,000 Frames/s Programmable Vision Chip with Variable Resolution and Row-Pixel-Mixed Parallel Image Processors

    PubMed Central

    Lin, Qingyu; Miao, Wei; Zhang, Wancheng; Fu, Qiuyu; Wu, Nanjian

    2009-01-01

    A programmable vision chip with variable resolution and row-pixel-mixed parallel image processors is presented. The chip consists of a CMOS sensor array, with row-parallel 6-bit Algorithmic ADCs, row-parallel gray-scale image processors, pixel-parallel SIMD Processing Element (PE) array, and instruction controller. The resolution of the image in the chip is variable: high resolution for a focused area and low resolution for general view. It implements gray-scale and binary mathematical morphology algorithms in series to carry out low-level and mid-level image processing and sends out features of the image for various applications. It can perform image processing at over 1,000 frames/s (fps). A prototype chip with 64 × 64 pixels resolution and 6-bit gray-scale image is fabricated in 0.18 μm Standard CMOS process. The area size of chip is 1.5 mm × 3.5 mm. Each pixel size is 9.5 μm × 9.5 μm and each processing element size is 23 μm × 29 μm. The experiment results demonstrate that the chip can perform low-level and mid-level image processing and it can be applied in the real-time vision applications, such as high speed target tracking. PMID:22454565

  11. The neuron net method for processing the clear pixels and method of the analytical formulas for processing the cloudy pixels of POLDER instrument images

    NASA Astrophysics Data System (ADS)

    Melnikova, I.; Mukai, S.; Vasilyev, A.

    Data of remote measurements of reflected radiance with the POLDER instrument on board of ADEOS satellite are used for retrieval of the optical thickness, single scattering albedo and phase function parameter of cloudy and clear atmosphere. The method of perceptron neural network that from input values of multiangle radiance and Solar incident angle allows to obtain surface albedo, the optical thickness, single scattering albedo and phase function parameter in case of clear sky. Two last parameters are determined as optical average for atmospheric column. The calculation of solar radiance with using the MODTRAN-3 code with taking into account multiple scattering is accomplished for neural network learning. All mentioned parameters were randomly varied on the base of statistical models of possible measured parameters variation. Results of processing one frame of remote observation that consists from 150,000 pixels are presented. The methodology elaborated allows operative determining optical characteristics as cloudy as clear atmosphere. Further interpretation of these results gives the possibility to extract the information about total contents of atmospheric aerosols and absorbing gases in the atmosphere and create models of the real cloudiness An analytical method of interpretation that based on asymptotic formulas of multiple scattering theory is applied to remote observations of reflected radiance in case of cloudy pixel. Details of the methodology and error analysis were published and discussed earlier. Here we present results of data processing of pixel size 6x6 km In many studies the optical thickness is evaluated earlier in the assumption of the conservative scattering. But in case of true absorption in clouds the large errors in parameter obtained are possible. The simultaneous retrieval of two parameters at every wavelength independently is the advantage comparing with earlier studies. The analytical methodology is based on the transfer theory asymptotic

  12. TOPICAL REVIEW: Physics of magnetic resonance imaging: from spin to pixel

    NASA Astrophysics Data System (ADS)

    Gossuin, Yves; Hocq, Aline; Gillis, Pierre; Vuong, Quoc Lam

    2010-06-01

    Magnetic resonance imaging has become a major diagnostic tool in modern medicine. MRI makes it possible to obtain highly contrasted body images without ionizing radiation. Using the magnetic properties of hydrogen protons, MRI is at the crossroads between physics, electronics, signal processing and informatics. In this introductory text, the basic physical principles of MRI image formation are explained. Some important clinical applications are also presented.

  13. X-ray tests of a Pixel Array Detector for coherent x-ray imaging at the Linac Coherent Light Source

    NASA Astrophysics Data System (ADS)

    Koerner, L. J.; Philipp, H. T.; Hromalik, M. S.; Tate, M. W.; Gruner, S. M.

    2009-03-01

    Test results are presented of a pixel array detector (PAD) developed for x-ray imaging at the Stanford Linear Coherent Light Source (LCLS). The basic module of the PAD consists of two bump-bonded chips: a reverse-biased silicon diode chip of 185 × 194 pixels, each of which is coupled by bump-bonds to a charge integrating CMOS ASIC with digitization in each pixel. The LCLS experiment requires a high signal-to-noise ratio for detection of single 8 keV x-rays, a pixel full-well exceeding 1,000 8 keV x-rays, a frame-rate of 120 Hz, and the ability to handle the arrival of thousands of x-rays per pixel in tens of femtoseconds. Measurements have verified a pixel full-well value of 2,700 8 keV x-rays. Single 8 keV photon detection has been shown with a signal-to-noise ratio of >6. Line-spread response measurements confirmed charge spreading to be limited to nearest neighbor pixels. Modules still functioned after dosages up to 75 Mrad(Si) at the detector face. Work is proceeding to incorporate an array of modules into a large-area detector.

  14. Investigation on automatic change detection using pixel-changes and DSM-changes with ALOS-PRISM triplet images

    NASA Astrophysics Data System (ADS)

    Sasagawa, A.; Baltsavias, E.; Kocaman Aksakal, S.; Wegner, J. D.

    2013-10-01

    A new algorithm for automatic change detection is presented. It detects a pixel-change and DSM-change from two orthoimages and two DSMs, then it extracts the polygons in elevation-changed areas. Pixel-change is detected by using least squares fitting technique. This method can extract the visible changed areas between two orthoimages, while DSM-change is detected by difference DSM. From these two changes, polygons in elevation-changed areas are extracted using the longest matched line selection techniques. This method can automatically detect not only visible changed areas such as vegetated areas, new road construction areas and so on, but also elevation-changed areas such as new building construction, land improvement areas and so on with footprint polygon extraction. We have tested our method using the two sets of ALOS-PRISM triplet images observed over a testfield in Tsukuba, Japan. We confirmed that this method has an effect finding changed areas. Also we compared the number of extracted polygons between manual operation and our automatic method.

  15. Comparison Effectiveness of Pixel Based Classification and Object Based Classification Using High Resolution Image In Floristic Composition Mapping (Study Case: Gunung Tidar Magelang City)

    NASA Astrophysics Data System (ADS)

    Ardha Aryaguna, Prama; Danoedoro, Projo

    2016-11-01

    Developments of analysis remote sensing have same way with development of technology especially in sensor and plane. Now, a lot of image have high spatial and radiometric resolution, that's why a lot information. Vegetation object analysis such floristic composition got a lot advantage of that development. Floristic composition can be interpreted using a lot of method such pixel based classification and object based classification. The problems for pixel based method on high spatial resolution image are salt and paper who appear in result of classification. The purpose of this research are compare effectiveness between pixel based classification and object based classification for composition vegetation mapping on high resolution image Worldview-2. The results show that pixel based classification using majority 5×5 kernel windows give the highest accuracy between another classifications. The highest accuracy is 73.32% from image Worldview-2 are being radiometric corrected level surface reflectance, but for overall accuracy in every class, object based are the best between another methods. Reviewed from effectiveness aspect, pixel based are more effective then object based for vegetation composition mapping in Tidar forest.

  16. Pixel pitch and particle energy influence on the dark current distribution of neutron irradiated CMOS image sensors.

    PubMed

    Belloir, Jean-Marc; Goiffon, Vincent; Virmontois, Cédric; Raine, Mélanie; Paillet, Philippe; Duhamel, Olivier; Gaillardin, Marc; Molina, Romain; Magnan, Pierre; Gilard, Olivier

    2016-02-22

    The dark current produced by neutron irradiation in CMOS Image Sensors (CIS) is investigated. Several CIS with different photodiode types and pixel pitches are irradiated with various neutron energies and fluences to study the influence of each of these optical detector and irradiation parameters on the dark current distribution. An empirical model is tested on the experimental data and validated on all the irradiated optical imagers. This model is able to describe all the presented dark current distributions with no parameter variation for neutron energies of 14 MeV or higher, regardless of the optical detector and irradiation characteristics. For energies below 1 MeV, it is shown that a single parameter has to be adjusted because of the lower mean damage energy per nuclear interaction. This model and these conclusions can be transposed to any silicon based solid-state optical imagers such as CIS or Charged Coupled Devices (CCD). This work can also be used when designing an optical imager instrument, to anticipate the dark current increase or to choose a mitigation technique.

  17. Adaptive pixel-selection using chaotic map lattices for image cryptography

    NASA Astrophysics Data System (ADS)

    Sittigorn, Jirasak; Paithoonwattanakij, Kitti; Surawatpunya, Charray

    2014-01-01

    Chaotic theory has been used in cryptography application for generating a sequence of data that is close to pseudorandom number based on an adjusted initial condition and a parameter. However, data recovery becomes a crucial problem due to the precision of the parameters. This difficulty leads to limited usage of Chaotic-based cryptography especially for error sensitive applications such as voice cryptography. In order to enhance the encryption security and overcome this limitation, an Adaptive Pixel-Selection using Chaotic Map Lattices (APCML) is proposed. In APCML, the encryption sequence has been adaptively selected based on chaos generator. Moreover, the chaotic transformation and normalization boundary have been revised to alleviate the rounding error and inappropriate normalization boundary problems. In the experiments, the measurement indices of originality preservation, visual inspection, and statistical analysis are used to evaluate the performance of the proposed APCML compared to that of the original CML. Consequently, the APCML algorithm offers greater performance with full recovery of the original message.

  18. From Single Pixels to Many Megapixels: Progress in Astronomical Infrared Imaging from Space-borne Telescopes

    NASA Astrophysics Data System (ADS)

    Pipher, Judith

    2017-01-01

    In the 1960s, rocket infrared astronomy was in its infancy. The Cornell group planned a succession of rocket launches of a small cryogenically cooled telescope above much of the atmosphere. Cornell graduate students were tasked with hand-making single pixel detectors for the focal plane at wavelengths ranging from ~5 microns to just short of 1 mm. “Images” could only be constructed from scans of objects such as HII regions/giant molecular clouds, the galactic center, and of diffuse radiation from the various IR backgrounds. IRAS and COBE, followed by the KAO utilized ever more sensitive single IR detectors, and revolutionized our understanding of the Universe. The first IR arrays came onto the scene in the early 1970s - and in 1983 several experiments for the space mission SIRTF (later named Spitzer Space Telescope following launch 20 years later) were selected, all boasting (relatively small) arrays. Europe’s ISO and Herschel also employed arrays to good advantage, as has SOFIA, and now, many-megapixel IR arrays are sufficiently well-developed for upcoming space missions.

  19. Avoiding twisted pixels: ethical guidelines for the appropriate use and manipulation of scientific digital images.

    PubMed

    Cromey, Douglas W

    2010-12-01

    Digital imaging has provided scientists with new opportunities to acquire and manipulate data using techniques that were difficult or impossible to employ in the past. Because digital images are easier to manipulate than film images, new problems have emerged. One growing concern in the scientific community is that digital images are not being handled with sufficient care. The problem is twofold: (1) the very small, yet troubling, number of intentional falsifications that have been identified, and (2) the more common unintentional, inappropriate manipulation of images for publication. Journals and professional societies have begun to address the issue with specific digital imaging guidelines. Unfortunately, the guidelines provided often do not come with instructions to explain their importance. Thus they deal with what should or should not be done, but not the associated 'why' that is required for understanding the rules. This article proposes 12 guidelines for scientific digital image manipulation and discusses the technical reasons behind these guidelines. These guidelines can be incorporated into lab meetings and graduate student training in order to provoke discussion and begin to bring an end to the culture of "data beautification".

  20. Avoiding Twisted Pixels: Ethical Guidelines for the Appropriate Use and Manipulation of Scientific Digital Images

    PubMed Central

    2014-01-01

    Digital imaging has provided scientists with new opportunities to acquire and manipulate data using techniques that were difficult or impossible to employ in the past. Because digital images are easier to manipulate than film images, new problems have emerged. One growing concern in the scientific community is that digital images are not being handled with sufficient care. The problem is twofold: (1) the very small, yet troubling, number of intentional falsifications that have been identified, and (2) the more common unintentional, inappropriate manipulation of images for publication. Journals and professional societies have begun to address the issue with specific digital imaging guidelines. Unfortunately, the guidelines provided often do not come with instructions to explain their importance. Thus they deal with what should or should not be done, but not the associated ‘why’ that is required for understanding the rules. This article proposes 12 guidelines for scientific digital image manipulation and discusses the technical reasons behind these guidelines. These guidelines can be incorporated into lab meetings and graduate student training in order to provoke discussion and begin to bring an end to the culture of “data beautification”. PMID:20567932

  1. Noninvasive, near-field terahertz imaging of hidden objects using a single-pixel detector

    PubMed Central

    Stantchev, Rayko Ivanov; Sun, Baoqing; Hornett, Sam M.; Hobson, Peter A.; Gibson, Graham M.; Padgett, Miles J.; Hendry, Euan

    2016-01-01

    Terahertz (THz) imaging can see through otherwise opaque materials. However, because of the long wavelengths of THz radiation (λ = 400 μm at 0.75 THz), far-field THz imaging techniques suffer from low resolution compared to visible wavelengths. We demonstrate noninvasive, near-field THz imaging with subwavelength resolution. We project a time-varying, intense (>100 μJ/cm2) optical pattern onto a silicon wafer, which spatially modulates the transmission of synchronous pulse of THz radiation. An unknown object is placed on the hidden side of the silicon, and the far-field THz transmission corresponding to each mask is recorded by a single-element detector. Knowledge of the patterns and of the corresponding detector signal are combined to give an image of the object. Using this technique, we image a printed circuit board on the underside of a 115-μm-thick silicon wafer with ~100-μm (λ/4) resolution. With subwavelength resolution and the inherent sensitivity to local conductivity, it is possible to detect fissures in the circuitry wiring of a few micrometers in size. THz imaging systems of this type will have other uses too, where noninvasive measurement or imaging of concealed structures is necessary, such as in semiconductor manufacturing or in ex vivo bioimaging. PMID:27386577

  2. 1024 x 1024 pixel mid-wavelength and long-wavelength infrared QWIP focal plane arrays for imaging applications

    NASA Technical Reports Server (NTRS)

    Gunapala, S. D.; Bandara, S. V.; Liu, J. K.; Hill, C. J.; Rafol, S. B.; Mumolo, J. M.; Trinh, J. T.; Tidrow, M. Z.; LeVan, P. D.

    2005-01-01

    Mid-wavelength infrared (MWIR) and long-wavelength infrared (LWIR) 10(24) x 10(24) pixel quantum well infrared photodetector (QWIP) focal planes have been demonstrated with excellent imaging performance. The MWIR QWIP detector array has demonstrated a noise equivalent differential temperature (NEAT) of 17 mK at a 95 K operating temperature with f/2.5 optics at 300 K background and the LWIR detector array has demonstrated a NEAT of 13 mK at a 70 K operating temperature with the same optical and background conditions as the MWIR detector array after the subtraction of system noise. Both MWIR and LWIR focal planes have shown background limited performance (BLIP) at 90 K and 70 K operating temperatures respectively, with similar optical and background conditions. In this paper, we will discuss the performance in terms of quantum efficiency, NE(delta)T, uniformity, operability and modulation transfer functions.

  3. 640 x 512 Pixels Long-Wavelength Infrared (LWIR) Quantum-Dot Infrared Photodetector (QDIP) Imaging Focal Plane Array

    NASA Technical Reports Server (NTRS)

    Gunapala, Sarath D.; Bandara, Sumith V.; Hill, Cory J.; Ting, David Z.; Liu, John K.; Rafol, Sir B.; Blazejewski, Edward R.; Mumolo, Jason M.; Keo, Sam A.; Krishna, Sanjay; Chang, Y. -C.; Shott, Craig A.

    2007-01-01

    Epitaxially grown self-assembled. InAs-InGaAs-GaAs quantum dots (QDs) are exploited for the development of large-format long-wavelength infrared focal plane arrays (FPAs). The dot-in-a-well (DWELL) structures were experimentally shown to absorb both 45 degrees and normal incident light, therefore, a reflection grating structure was used to enhance the quantum efficiency. The devices exhibit peak responsivity out to 8.1 micrometers, with peak detectivity reaching approximately 1 X 10(exp 10) Jones at 77 K. The devices were fabricated into the first long-wavelength 640 x 512 pixel QD infrared photodetector imaging FPA, which has produced excellent infrared imagery with noise equivalent temperature difference of 40 mK at 60-K operating temperature.

  4. SU-C-201-03: Coded Aperture Gamma-Ray Imaging Using Pixelated Semiconductor Detectors

    SciTech Connect

    Joshi, S; Kaye, W; Jaworski, J; He, Z

    2015-06-15

    Purpose: Improved localization of gamma-ray emissions from radiotracers is essential to the progress of nuclear medicine. Polaris is a portable, room-temperature operated gamma-ray imaging spectrometer composed of two 3×3 arrays of thick CdZnTe (CZT) detectors, which detect gammas between 30keV and 3MeV with energy resolution of <1% FWHM at 662keV. Compton imaging is used to map out source distributions in 4-pi space; however, is only effective above 300keV where Compton scatter is dominant. This work extends imaging to photoelectric energies (<300keV) using coded aperture imaging (CAI), which is essential for localization of Tc-99m (140keV). Methods: CAI, similar to the pinhole camera, relies on an attenuating mask, with open/closed elements, placed between the source and position-sensitive detectors. Partial attenuation of the source results in a “shadow” or count distribution that closely matches a portion of the mask pattern. Ideally, each source direction corresponds to a unique count distribution. Using backprojection reconstruction, the source direction is determined within the field of view. The knowledge of 3D position of interaction results in improved image quality. Results: Using a single array of detectors, a coded aperture mask, and multiple Co-57 (122keV) point sources, image reconstruction is performed in real-time, on an event-by-event basis, resulting in images with an angular resolution of ∼6 degrees. Although material nonuniformities contribute to image degradation, the superposition of images from individual detectors results in improved SNR. CAI was integrated with Compton imaging for a seamless transition between energy regimes. Conclusion: For the first time, CAI has been applied to thick, 3D position sensitive CZT detectors. Real-time, combined CAI and Compton imaging is performed using two 3×3 detector arrays, resulting in a source distribution in space. This system has been commercialized by H3D, Inc. and is being acquired for

  5. Simulation of active-edge pixelated CdTe radiation detectors

    NASA Astrophysics Data System (ADS)

    Duarte, D. D.; Lipp, J. D.; Schneider, A.; Seller, P.; Veale, M. C.; Wilson, M. D.; Baker, M. A.; Sellin, P. J.

    2016-01-01

    The edge surfaces of single crystal CdTe play an important role in the electronic properties and performance of this material as an X-ray and γ-ray radiation detector. Edge effects have previously been reported to reduce the spectroscopic performance of the edge pixels in pixelated CdTe radiation detectors without guard bands. A novel Technology Computer Aided Design (TCAD) model based on experimental data has been developed to investigate these effects. The results presented in this paper show how localized low resistivity surfaces modify the internal electric field of CdTe creating potential wells. These result in a reduction of charge collection efficiency of the edge pixels, which compares well with experimental data.

  6. Pixel-level multisensor image fusion based on matrix completion and robust principal component analysis

    NASA Astrophysics Data System (ADS)

    Wang, Zhuozheng; Deller, J. R.; Fleet, Blair D.

    2016-01-01

    Acquired digital images are often corrupted by a lack of camera focus, faulty illumination, or missing data. An algorithm is presented for fusion of multiple corrupted images of a scene using the lifting wavelet transform. The method employs adaptive fusion arithmetic based on matrix completion and self-adaptive regional variance estimation. Characteristics of the wavelet coefficients are used to adaptively select fusion rules. Robust principal component analysis is applied to low-frequency image components, and regional variance estimation is applied to high-frequency components. Experiments reveal that the method is effective for multifocus, visible-light, and infrared image fusion. Compared with traditional algorithms, the new algorithm not only increases the amount of preserved information and clarity but also improves robustness.

  7. Chlorophyll Concentration Estimates for Coastal Waters using Pixel-Based Atmospheric Correction of Landsat Images

    NASA Astrophysics Data System (ADS)

    Kouba, E.; Xie, H.

    2014-12-01

    Ocean color analysis is more challenging for coastal regions than the global ocean due the effects of optical brightness, shallow and turbid water, higher phytoplankton growth rates, and the complex geometry of coastal bays and estuaries. Also, one of the key atmospheric correction assumptions (zero water leaving radiance in the near infrared) is not valid for these complex conditions. This makes it difficult to estimate the spectral radiance noise caused by atmospheric aerosols, which can vary rapidly with time and space. This project evaluated using Landsat-7 ETM+ observations over a set of coastal bays, and allowing atmospheric correction calculations to vary with time and location as much as practical. Precise satellite orbit vector data was combined with operational weather and climate data to create interpolated arrays of atmospheric profiles which varied with time and location, allowing separate calculation of the Rayleigh and aerosol radiance corrections for all pixels. The resulting normalized water-leaving radiance values were compared with chlorophyll fluorescence measurements made at five in-situ stations inside a set of Texas coastal bays: the Mission-Aransas National Estuarine Research Reserve. Curve-fitting analysis showed it was possible to estimate chlorophyll surface area concentrations by using ETM+ water-leaving radiance values and a third-order polynomial equation. Two pairs of ETM+ bands were identified as inputs (Bands 1 and 3, and the Log10 values of Bands 3 and 4), both achieving R2 of 0.69. Additional research efforts were recommended to obtain additional data, identify better curve fitting equations, and potentially extend the radiative transfer model into the water column.

  8. Seismic zonation of Port-Au-Prince using pixel- and object-based imaging analysis methods on ASTER GDEM

    USGS Publications Warehouse

    Yong, Alan; Hough, Susan E.; Cox, Brady R.; Rathje, Ellen M.; Bachhuber, Jeff; Dulberg, Ranon; Hulslander, David; Christiansen, Lisa; and Abrams, Michael J.

    2011-01-01

    We report about a preliminary study to evaluate the use of semi-automated imaging analysis of remotely-sensed DEM and field geophysical measurements to develop a seismic-zonation map of Port-au-Prince, Haiti. For in situ data, VS30 values are derived from the MASW technique deployed in and around the city. For satellite imagery, we use an ASTER GDEM of Hispaniola. We apply both pixel- and object-based imaging methods on the ASTER GDEM to explore local topography (absolute elevation values) and classify terrain types such as mountains, alluvial fans and basins/near-shore regions. We assign NEHRP seismic site class ranges based on available VS30 values. A comparison of results from imagery-based methods to results from traditional geologic-based approaches reveals good overall correspondence. We conclude that image analysis of RS data provides reliable first-order site characterization results in the absence of local data and can be useful to refine detailed site maps with sparse local data.

  9. Seismic-zonation of Port-au-Prince using pixel- and object-based imaging analysis methods on ASTER GDEM

    USGS Publications Warehouse

    Yong, A.; Hough, S.E.; Cox, B.R.; Rathje, E.M.; Bachhuber, J.; Dulberg, R.; Hulslander, D.; Christiansen, L.; Abrams, M.J.

    2011-01-01

    We report about a preliminary study to evaluate the use of semi-automated imaging analysis of remotely-sensed DEM and field geophysical measurements to develop a seismic-zonation map of Port-au-Prince, Haiti. For in situ data, Vs30 values are derived from the MASW technique deployed in and around the city. For satellite imagery, we use an ASTER GDEM of Hispaniola. We apply both pixel- and object-based imaging methods on the ASTER GDEM to explore local topography (absolute elevation values) and classify terrain types such as mountains, alluvial fans and basins/near-shore regions. We assign NEHRP seismic site class ranges based on available Vs30 values. A comparison of results from imagery-based methods to results from traditional geologic-based approaches reveals good overall correspondence. We conclude that image analysis of RS data provides reliable first-order site characterization results in the absence of local data and can be useful to refine detailed site maps with sparse local data. ?? 2011 American Society for Photogrammetry and Remote Sensing.

  10. Evaluation of Origin Ensemble algorithm for image reconstruction for pixelated solid-state detectors with large number of channels

    NASA Astrophysics Data System (ADS)

    Kolstein, M.; De Lorenzo, G.; Mikhaylova, E.; Chmeissani, M.; Ariño, G.; Calderón, Y.; Ozsahin, I.; Uzun, D.

    2013-04-01

    The Voxel Imaging PET (VIP) Pathfinder project intends to show the advantages of using pixelated solid-state technology for nuclear medicine applications. It proposes designs for Positron Emission Tomography (PET), Positron Emission Mammography (PEM) and Compton gamma camera detectors with a large number of signal channels (of the order of 106). For PET scanners, conventional algorithms like Filtered Back-Projection (FBP) and Ordered Subset Expectation Maximization (OSEM) are straightforward to use and give good results. However, FBP presents difficulties for detectors with limited angular coverage like PEM and Compton gamma cameras, whereas OSEM has an impractically large time and memory consumption for a Compton gamma camera with a large number of channels. In this article, the Origin Ensemble (OE) algorithm is evaluated as an alternative algorithm for image reconstruction. Monte Carlo simulations of the PET design are used to compare the performance of OE, FBP and OSEM in terms of the bias, variance and average mean squared error (MSE) image quality metrics. For the PEM and Compton camera designs, results obtained with OE are presented.

  11. Evaluation of Origin Ensemble algorithm for image reconstruction for pixelated solid-state detectors with large number of channels

    PubMed Central

    Kolstein, M.; De Lorenzo, G.; Mikhaylova, E.; Chmeissani, M.; Ariño, G.; Calderón, Y.; Ozsahin, I.; Uzun, D.

    2013-01-01

    The Voxel Imaging PET (VIP) Pathfinder project intends to show the advantages of using pixelated solid-state technology for nuclear medicine applications. It proposes designs for Positron Emission Tomography (PET), Positron Emission Mammography (PEM) and Compton gamma camera detectors with a large number of signal channels (of the order of 106). For PET scanners, conventional algorithms like Filtered Back-Projection (FBP) and Ordered Subset Expectation Maximization (OSEM) are straightforward to use and give good results. However, FBP presents difficulties for detectors with limited angular coverage like PEM and Compton gamma cameras, whereas OSEM has an impractically large time and memory consumption for a Compton gamma camera with a large number of channels. In this article, the Origin Ensemble (OE) algorithm is evaluated as an alternative algorithm for image reconstruction. Monte Carlo simulations of the PET design are used to compare the performance of OE, FBP and OSEM in terms of the bias, variance and average mean squared error (MSE) image quality metrics. For the PEM and Compton camera designs, results obtained with OE are presented. PMID:23814604

  12. Evaluation of Origin Ensemble algorithm for image reconstruction for pixelated solid-state detectors with large number of channels.

    PubMed

    Kolstein, M; De Lorenzo, G; Mikhaylova, E; Chmeissani, M; Ariño, G; Calderón, Y; Ozsahin, I; Uzun, D

    2013-04-29

    The Voxel Imaging PET (VIP) Pathfinder project intends to show the advantages of using pixelated solid-state technology for nuclear medicine applications. It proposes designs for Positron Emission Tomography (PET), Positron Emission Mammography (PEM) and Compton gamma camera detectors with a large number of signal channels (of the order of 10(6)). For PET scanners, conventional algorithms like Filtered Back-Projection (FBP) and Ordered Subset Expectation Maximization (OSEM) are straightforward to use and give good results. However, FBP presents difficulties for detectors with limited angular coverage like PEM and Compton gamma cameras, whereas OSEM has an impractically large time and memory consumption for a Compton gamma camera with a large number of channels. In this article, the Origin Ensemble (OE) algorithm is evaluated as an alternative algorithm for image reconstruction. Monte Carlo simulations of the PET design are used to compare the performance of OE, FBP and OSEM in terms of the bias, variance and average mean squared error (MSE) image quality metrics. For the PEM and Compton camera designs, results obtained with OE are presented.

  13. A Low-Noise CMOS THz Imager Based on Source Modulation and an In-Pixel High-Q Passive Switched-Capacitor N-Path Filter

    PubMed Central

    Boukhayma, Assim; Dupret, Antoine; Rostaing, Jean-Pierre; Enz, Christian

    2016-01-01

    This paper presents the first low noise complementary metal oxide semiconductor (CMOS) terahertz (THz) imager based on source modulation and in-pixel high-Q filtering. The 31×31 focal plane array has been fully integrated in a 0.13μm standard CMOS process. The sensitivity has been improved significantly by modulating the active THz source that lights the scene and performing on-chip high-Q filtering. Each pixel encompass a broadband bow tie antenna coupled to an N-type metal-oxide-semiconductor (NMOS) detector that shifts the THz radiation, a low noise adjustable gain amplifier and a high-Q filter centered at the modulation frequency. The filter is based on a passive switched-capacitor (SC) N-path filter combined with a continuous-time broad-band Gm-C filter. A simplified analysis that helps in designing and tuning the passive SC N-path filter is provided. The characterization of the readout chain shows that a Q factor of 100 has been achieved for the filter with a good matching between the analytical calculation and the measurement results. An input-referred noise of 0.2μV RMS has been measured. Characterization of the chip with different THz wavelengths confirms the broadband feature of the antenna and shows that this THz imager reaches a total noise equivalent power of 0.6 nW at 270 GHz and 0.8 nW at 600 GHz. PMID:26950131

  14. X-RAY ACTIVE MATRIX PIXEL SENSORS BASEDON J-FET TECHNOLOGY DEVELOPED FOR THE LINAC COHERENT LIGHT SOURCE.

    SciTech Connect

    CARINI,G.A.; CHEN, W.; LI, Z.; REHAK, P.; SIDDONS, D.P.

    2007-10-29

    An X-ray Active Matrix Pixel Sensor (XAMPS) is being developed for recording data for the X-ray Pump Probe experiment at the Linac Coherent Light Source (LCLS). Special attention has to be paid to some technological challenges that this design presents. New processes were developed and refined to address problems encountered during previous productions of XAMPS. The development of these critical steps and corresponding tests results are reported here.

  15. Thin n-in-p planar pixel sensors and active edge sensors for the ATLAS upgrade at HL-LHC

    NASA Astrophysics Data System (ADS)

    Terzo, S.; Macchiolo, A.; Nisius, R.; Paschen, B.

    2014-12-01

    Silicon pixel modules employing n-in-p planar sensors with an active thickness of 200 μm, produced at CiS, and 100-200 μm thin active/slim edge sensor devices, produced at VTT in Finland have been interconnected to ATLAS FE-I3 and FE-I4 read-out chips. The thin sensors are designed for high energy physics collider experiments to ensure radiation hardness at high fluences. Moreover, the active edge technology of the VTT production maximizes the sensitive region of the assembly, allowing for a reduced overlap of the modules in the pixel layer close to the beam pipe. The CiS production includes also four chip sensors according to the module geometry planned for the outer layers of the upgraded ATLAS pixel detector to be operated at the HL-LHC. The modules have been characterized using radioactive sources in the laboratory and with high precision measurements at beam tests to investigate the hit efficiency and charge collection properties at different bias voltages and particle incidence angles. The performance of the different sensor thicknesses and edge designs are compared before and after irradiation up to a fluence of 1.4 × 1016 neq/cm2.

  16. Solid-state Image Sensor with Focal-plane Digital Photon-counting Pixel Array

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R.; Pain, Bedabrata

    1997-01-01

    A solid-state focal-plane imaging system comprises an NxN array of high gain. low-noise unit cells. each unit cell being connected to a different one of photovoltaic detector diodes, one for each unit cell, interspersed in the array for ultra low level image detection and a plurality of digital counters coupled to the outputs of the unit cell by a multiplexer(either a separate counter for each unit cell or a row of N of counters time shared with N rows of digital counters). Each unit cell includes two self-biasing cascode amplifiers in cascade for a high charge-to-voltage conversion gain (greater than 1mV/e(-)) and an electronic switch to reset input capacitance to a reference potential in order to be able to discriminate detection of an incident photon by the photoelectron (e(-))generated in the detector diode at the input of the first cascode amplifier in order to count incident photons individually in a digital counter connected to the output of the second cascade amplifier. Reseting the input capacitance and initiating self-biasing of the amplifiers occurs every clock cycle of an integratng period to enable ultralow light level image detection by the may of photovoltaic detector diodes under such ultralow light level conditions that the photon flux will statistically provide only a single photon at a time incident on anyone detector diode during any clock cycle.

  17. A SPAD-based 3D imager with in-pixel TDC for 145ps-accuracy ToF measurement

    NASA Astrophysics Data System (ADS)

    Vornicu, I.; Carmona-Galán, R.; Rodríguez-Vázquez, Á.

    2015-03-01

    The design and measurements of a CMOS 64 × 64 Single-Photon Avalanche-Diode (SPAD) array with in-pixel Time-to-Digital Converter (TDC) are presented. This paper thoroughly describes the imager at architectural and circuit level with particular emphasis on the characterization of the SPAD-detector ensemble. It is aimed to 2D imaging and 3D image reconstruction in low light environments. It has been fabricated in a standard 0.18μm CMOS process, i. e. without high voltage or low noise features. In these circumstances, we are facing a high number of dark counts and low photon detection efficiency. Several techniques have been applied to ensure proper functionality, namely: i) time-gated SPAD front-end with fast active-quenching/recharge circuit featuring tunable dead-time, ii) reverse start-stop scheme, iii) programmable time resolution of the TDC based on a novel pseudo-differential voltage controlled ring oscillator with fast start-up, iv) a global calibration scheme against temperature and process variation. Measurements results of individual SPAD-TDC ensemble jitter, array uniformity and time resolution programmability are also provided.

  18. Per-Pixel Coded Exposure for High-Speed and High-Resolution Imaging Using a Digital Micromirror Device Camera.

    PubMed

    Feng, Wei; Zhang, Fumin; Qu, Xinghua; Zheng, Shiwei

    2016-03-04

    High-speed photography is an important tool for studying rapid physical phenomena. However, low-frame-rate CCD (charge coupled device) or CMOS (complementary metal oxide semiconductor) camera cannot effectively capture the rapid phenomena with high-speed and high-resolution. In this paper, we incorporate the hardware restrictions of existing image sensors, design the sampling functions, and implement a hardware prototype with a digital micromirror device (DMD) camera in which spatial and temporal information can be flexibly modulated. Combined with the optical model of DMD camera, we theoretically analyze the per-pixel coded exposure and propose a three-element median quicksort method to increase the temporal resolution of the imaging system. Theoretically, this approach can rapidly increase the temporal resolution several, or even hundreds, of times without increasing bandwidth requirements of the camera. We demonstrate the effectiveness of our method via extensive examples and achieve 100 fps (frames per second) gain in temporal resolution by using a 25 fps camera.

  19. High-Sensitivity X-ray Polarimetry with Amorphous Silicon Active-Matrix Pixel Proportional Counters

    NASA Technical Reports Server (NTRS)

    Black, J. K.; Deines-Jones, P.; Jahoda, K.; Ready, S. E.; Street, R. A.

    2003-01-01

    Photoelectric X-ray polarimeters based on pixel micropattern gas detectors (MPGDs) offer order-of-magnitude improvement in sensitivity over more traditional techniques based on X-ray scattering. This new technique places some of the most interesting astronomical observations within reach of even a small, dedicated mission. The most sensitive instrument would be a photoelectric polarimeter at the focus of 2 a very large mirror, such as the planned XEUS. Our efforts are focused on a smaller pathfinder mission, which would achieve its greatest sensitivity with large-area, low-background, collimated polarimeters. We have recently demonstrated a MPGD polarimeter using amorphous silicon thin-film transistor (TFT) readout suitable for the focal plane of an X-ray telescope. All the technologies used in the demonstration polarimeter are scalable to the areas required for a high-sensitivity collimated polarimeter. Leywords: X-ray polarimetry, particle tracking, proportional counter, GEM, pixel readout

  20. Characterization of CMOS Active Pixel Sensors for particle detection: Beam test of the four-sensors RAPS03 stacked system

    NASA Astrophysics Data System (ADS)

    Passeri, Daniele; Servoli, Leonello; Biagetti, Daniele; Meroli, Stefano

    2010-05-01

    In this work, in order to check the suitability of CMOS Active Pixel Sensors (APS) detectors for vertexing/tracking applications, four stacked CMOS APS sensors featuring 256×256 pixels with 10×10 μm 2 size have been tested at the INFN Beam Test Facility (BFT), Frascati (Rome). For this purpose, a dedicated mechanical and electrical set-up has been devised and implemented, allowing for the simultaneous read-out of four sensors arranged in a stacked structure. A compact and fast system (up to 64 MHz read-out clock) based on external ADCs and FPGA allows for the PC communication through USB2.0. Preliminary results in terms of track reconstructions of electrons of different energies (up to 496 MeV) are presented. This work has been carried out within the framework of the SHARPS project, supported by INFN.

  1. Mapping Electrical Crosstalk in Pixelated Sensor Arrays

    NASA Technical Reports Server (NTRS)

    Seshadri, Suresh (Inventor); Cole, David (Inventor); Smith, Roger M (Inventor); Hancock, Bruce R. (Inventor)

    2013-01-01

    The effects of inter pixel capacitance in a pixilated array may be measured by first resetting all pixels in the array to a first voltage, where a first image is read out, followed by resetting only a subset of pixels in the array to a second voltage, where a second image is read out, where the difference in the first and second images provide information about the inter pixel capacitance. Other embodiments are described and claimed.

  2. Mapping Electrical Crosstalk in Pixelated Sensor Arrays

    NASA Technical Reports Server (NTRS)

    Seshadri, Suresh (Inventor); Cole, David (Inventor); Smith, Roger M. (Inventor); Hancock, Bruce R. (Inventor)

    2017-01-01

    The effects of inter pixel capacitance in a pixilated array may be measured by first resetting all pixels in the array to a first voltage, where a first image is read out, followed by resetting only a subset of pixels in the array to a second voltage, where a second image is read out, where the difference in the first and second images provide information about the inter pixel capacitance. Other embodiments are described and claimed.

  3. Spectrum-per-Pixel Cathodoluminescence Imaging of CdTe Thin-Film Bevels

    SciTech Connect

    Moseley, John; Al-Jassim, Mowafak M.; Burst, James; Guthrey, Harvey L.; Metzger, Wyatt K.

    2016-11-21

    We conduct T=6 K cathodoluminescence (CL) spectrum imaging with a nano-scale electron beam on beveled surfaces of CdTe thin-films at different critical stages of standard CdTe device fabrication. The through-thickness total CL intensity profiles are consistent with a reduction in grain boundary recombination due to the CdCl2 treatment. Color-coded maps of the low-temperature luminescence transition energies reveal that CdTe thin films have remarkably non-uniform opto-electronic properties, which depend strongly on sample processing history. The grain-to-grain S content in the interdiffused CdTe/CdS region is estimated from a sample size of thirty-five grains, and the S content in adjacent grains varies significantly in CdCl2-treated samples. A low-temperature luminescence model is developed to interpret spectral behavior at grain boundaries and grain interiors.

  4. From pixel to voxel: a deeper view of biological tissue by 3D mass spectral imaging

    PubMed Central

    Ye, Hui; Greer, Tyler; Li, Lingjun

    2011-01-01

    Three dimensional mass spectral imaging (3D MSI) is an exciting field that grants the ability to study a broad mass range of molecular species ranging from small molecules to large proteins by creating lateral and vertical distribution maps of select compounds. Although the general premise behind 3D MSI is simple, factors such as choice of ionization method, sample handling, software considerations and many others must be taken into account for the successful design of a 3D MSI experiment. This review provides a brief overview of ionization methods, sample preparation, software types and technological advancements driving 3D MSI research of a wide range of low- to high-mass analytes. Future perspectives in this field are also provided to conclude that the positive and promises ever-growing applications in the biomedical field with continuous developments of this powerful analytical tool. PMID:21320052

  5. Correction of defective pixels for medical and space imagers based on Ising Theory

    NASA Astrophysics Data System (ADS)

    Cohen, Eliahu; Shnitser, Moriel; Avraham, Tsvika; Hadar, Ofer

    2014-09-01

    We propose novel models for image restoration based on statistical physics. We investigate the affinity between these fields and describe a framework from which interesting denoising algorithms can be derived: Ising-like models and simulated annealing techniques. When combined with known predictors such as Median and LOCO-I, these models become even more effective. In order to further examine the proposed models we apply them to two important problems: (i) Digital Cameras in space damaged from cosmic radiation. (ii) Ultrasonic medical devices damaged from speckle noise. The results, as well as benchmark and comparisons, suggest in most of the cases a significant gain in PSNR and SSIM in comparison to other filters.

  6. iCATSI: multi-pixel imaging differential spectroradiometer for standoff detection and quantification of chemical threats

    NASA Astrophysics Data System (ADS)

    Prel, Florent; Moreau, Louis; Lavoie, Hugo; Bouffard, François; Thériault, Jean-Marc; Vallieres, Christian; Roy, Claude; Dubé, Denis

    2011-11-01

    Homeland security and first responders are often faced with safety situations involving the identification of unknown volatile chemicals. Examples include industrial fires, chemical warfare, industrial leak, etc. The Improved Compact ATmospheric Sounding Interferometer (iCATSI) sensor has been developed to investigate the standoff detection and identification of toxic industrial chemicals (TICs), chemical warfare agents (CWA) and other chemicals. iCATSI is a combination of the CATSI instrument, a standoff differential FTIR optimised for the characterization of chemicals and the MR-i, the hyperspectral imaging spectroradiometer of ABB Bomem based on the proven MR spectroradiometers. The instrument is equipped with a dual-input telescope to perform optical background subtraction. The resulting signal is the difference between the spectral radiance entering each input port. With that method, the signal from the background is automatically removed from the signal of the target of interest. The iCATSI sensor is able to detect, spectrally resolve and identify 5 meters plumes up to 5 km range. The instrument is capable of sensing in the VLWIR (cut-off near 14 μm) to support research related to standoff chemical detection. In one of its configurations, iCATSI produces three 24 × 16 spectral images per second from 5.5 to 14 μm at a spectral resolution of 16 cm-1. In another configuration, iCATSI produces from two to four spectral images per second of 256 × 256 pixels from 8 to 13 μm with the same spectral resolution. Overview of the capabilities of the instrument and results from tests and field trials will be presented.

  7. Spectroscopic performance of DEPFET active pixel sensor prototypes suitable for the high count rate Athena WFI detector

    NASA Astrophysics Data System (ADS)

    Müller-Seidlitz, Johannes; Andritschke, Robert; Bähr, Alexander; Meidinger, Norbert; Ott, Sabine; Richter, Rainer H.; Treberspurg, Wolfgang; Treis, Johannes

    2016-07-01

    The focal plane of the WFI of Athena consists of two sensors. One features a large field of view of 40' X 40' and one is forseen to be used for bright point like sources. Both parts base on DEPFET active pixel sensors. To fulfil the count rate requirement for the smaller sensor of less than 1% pile-up for a one Crab source it has to have a sufficient high frame rate. Since therefore the readout becomes a large fraction of the total photon integration time, the probability of measurements with incomplete signals increases. A shutter would solve the problem of these so called misfits but is not in agreement with the required high throughput of more than 80%. The Infinipix design has implemented a storage in addition to separate the collection and the readout of the charges without discarding them. Its working principle was successfully shown by Bähr et al.1 on single pixel level. For the further development three layout variants were tested on a 32 X 32 pixel array scale. The measurements of the spectroscopic performance show very promising results even for the intended readout speed for the Athena WFI of 2:5 μs per sensor row. Although, there are still layout and technology improvements necessary to ensure the reliability needed for space missions. In this paper we present the measurement results on the comparison of the three prototype layout variants.

  8. Active pixel sensors in AMS H18/H35 HV-CMOS technology for the ATLAS HL-LHC upgrade

    NASA Astrophysics Data System (ADS)

    Ristic, Branislav

    2016-09-01

    Deep sub micron HV-CMOS processes offer the opportunity for sensors built by industry standard techniques while being HV tolerant, making them good candidates for drift-based, fast collecting, thus radiation-hard pixel detectors. For the upgrade of the ATLAS Pixel Detector towards the HL-LHC requirements, active pixel sensors in HV-CMOS technology were investigated. These implement signal processing electronics in deep n-wells, which also act as collecting electrodes. The deep n-wells allow for bias voltages up to 150 V leading to a depletion depth of several 10 μm. Prototype sensors in the AMS H18 180 nm and H35 350 nm HV-CMOS processes were thoroughly tested in lab measurements as well as in testbeam experiments. Irradiations with X-rays and protons revealed a tolerance to ionizing doses of 1 Grad while Edge-TCT studies assessed the effects of radiation on the charge collection. The sensors showed high detection efficiencies after neutron irradiation to 1015neq cm-2 in testbeam experiments. A full reticle size demonstrator chip, implemented in the H35 process is being submitted to prove the large scale feasibility of the HV-CMOS concept.

  9. Non-Uniform Object-Space Pixelation (NUOP) for Penalized Maximum-Likelihood Image Reconstruction for a Single Photon Emission Microscope System

    PubMed Central

    Meng, L. J.; Li, Nan

    2016-01-01

    This paper presents a non-uniform object-space pixelation (NUOP) approach for image reconstruction using the penalized maximum likelihood methods. This method was developed for use with a single photon emission microscope (SPEM) system that offers an ultrahigh spatial resolution for a targeted local region inside mouse brain. In this approach, the object-space is divided with non-uniform pixel sizes, which are chosen adaptively based on object-dependent criteria. These include (a) some known characteristics of a target-region, (b) the associated Fisher Information that measures the weighted correlation between the responses of the system to gamma ray emissions occurred at different spatial locations, and (c) the linear distance from a given location to the target-region. In order to quantify the impact of this non-uniform pixelation approach on image quality, we used the Modified Uniform Cramer-Rao bound (MUCRB) to evaluate the local resolution-variance and bias-variance tradeoffs achievable with different pixelation strategies. As demonstrated in this paper, an efficient object-space pixelation could improve the speed of computation by 1–2 orders of magnitude, whilst maintaining an excellent reconstruction for the target-region. This improvement is crucial for making the SPEM system a practical imaging tool for mouse brain studies. The proposed method also allows rapid computation of the first and second order statistics of reconstructed images using analytical approximations, which is the key for the evaluation of several analytical system performance indices for system design and optimization.

  10. Super-resolution of multi-pixel and sub-pixel images for the SDI. Final report. [SDI (Strategic Defense Initiative)

    SciTech Connect

    Not Available

    1993-06-08

    The recent profound shift in the global balance of power in favor of the United States of America has had major repercussions on Strategic Defense Initiative (SDI) planning. In particular, the focus has shifted from the provision of protection for the United States against a massive raid, involving possibly thousands of reentry vehicles, to defense against a much more limited attack which could now, however, be launched from any part of the world. Additionally, the United States is seeking to protect its forces and allies overseas, and in the task of missile detection and tracking, allowance must now be made for trajectories which can begin and end in almost any inhabited area of the globe. Thus SDI demands on surveillance technology have been significantly expanded. Space-based imaging systems will play a vital role in the surveillance task. In this report a description is first given of a typical scenario. The potential imaging problems are then examined, the mathematical background is discussed, and the innovative algorithms which have been developed for correcting and enhancing the performance of the imaging sensor are described.

  11. Pixelation Effects in Weak Lensing

    NASA Technical Reports Server (NTRS)

    High, F. William; Rhodes, Jason; Massey, Richard; Ellis, Richard

    2007-01-01

    Weak gravitational lensing can be used to investigate both dark matter and dark energy but requires accurate measurements of the shapes of faint, distant galaxies. Such measurements are hindered by the finite resolution and pixel scale of digital cameras. We investigate the optimum choice of pixel scale for a space-based mission, using the engineering model and survey strategy of the proposed Supernova Acceleration Probe as a baseline. We do this by simulating realistic astronomical images containing a known input shear signal and then attempting to recover the signal using the Rhodes, Refregier, and Groth algorithm. We find that the quality of shear measurement is always improved by smaller pixels. However, in practice, telescopes are usually limited to a finite number of pixels and operational life span, so the total area of a survey increases with pixel size. We therefore fix the survey lifetime and the number of pixels in the focal plane while varying the pixel scale, thereby effectively varying the survey size. In a pure trade-off for image resolution versus survey area, we find that measurements of the matter power spectrum would have minimum statistical error with a pixel scale of 0.09' for a 0.14' FWHM point-spread function (PSF). The pixel scale could be increased to 0.16' if images dithered by exactly half-pixel offsets were always available. Some of our results do depend on our adopted shape measurement method and should be regarded as an upper limit: future pipelines may require smaller pixels to overcome systematic floors not yet accessible, and, in certain circumstances, measuring the shape of the PSF might be more difficult than those of galaxies. However, the relative trends in our analysis are robust, especially those of the surface density of resolved galaxies. Our approach thus provides a snapshot of potential in available technology, and a practical counterpart to analytic studies of pixelation, which necessarily assume an idealized shape

  12. Imaging nervous system activity.

    PubMed

    Fields, R D; O'Donovan, M J

    2001-05-01

    Optical imaging methods rely upon visualization of three types of signals: (1) intrinsic optical signals, including light scattering and reflectance, birefringence, and spectroscopic changes of intrinsic molecules, such as NADH or oxyhemoglobin; (2) changes in fluorescence or absorbance of voltage-sensitive membrane dyes; and (3) changes in fluorescence or absorbance of calcium-sensitive indicator dyes. Of these, the most widely used approach is fluorescent microscopy of calcium-sensitive dyes. This unit describes protocols for the use of calcium-sensitive dyes and voltage-dependent dyes for studies of neuronal activity in culture, tissue slices, and en-bloc preparations of the central nervous system.

  13. A 2D 4×4 Channel Readout ASIC for Pixelated CdTe Detectors for Medical Imaging Applications

    PubMed Central

    Macias-Montero, Jose-Gabriel; Sarraj, Maher; Chmeissani, Mokhtar; Martínez, Ricardo; Puigdengoles, Carles

    2015-01-01

    We present a 16-channel readout integrated circuit (ROIC) with nanosecond-resolution time to digital converter (TDC) for pixelated Cadmium Telluride (CdTe) gamma-ray detectors. The 4 × 4 pixel array ROIC is the proof of concept of the 10 × 10 pixel array readout ASIC for positron-emission tomography (PET) scanner, positron-emission mammography (PEM) scanner, and Compton gamma camera. The electronics of each individual pixel integrates an analog front-end with switchable gain, an analog to digital converter (ADC), configuration registers, and a 4-state digital controller. For every detected photon, the pixel electronics provides the energy deposited in the detector with 10-bit resolution, and a fast trigger signal for time stamp. The ASIC contains the 16-pixel matrix electronics, a digital controller, five global voltage references, a TDC, a temperature sensor, and a band-gap based current reference. The ASIC has been fabricated with TSMC 0.25 μm mixed-signal CMOS technology and occupies an area of 5.3 mm × 6.8 mm. The TDC shows a resolution of 95.5 ps, a precision of 600 ps at full width half maximum (FWHM), and a power consumption of 130 μW. In acquisition mode, the total power consumption of every pixel is 200 μW. An equivalent noise charge (ENC) of 160 e−RMS at maximum gain and negative polarity conditions has been measured at room temperature. PMID:26744545

  14. A 2D 4×4 Channel Readout ASIC for Pixelated CdTe Detectors for Medical Imaging Applications.

    PubMed

    Macias-Montero, Jose-Gabriel; Sarraj, Maher; Chmeissani, Mokhtar; Martínez, Ricardo; Puigdengoles, Carles

    2015-10-01

    We present a 16-channel readout integrated circuit (ROIC) with nanosecond-resolution time to digital converter (TDC) for pixelated Cadmium Telluride (CdTe) gamma-ray detectors. The 4 × 4 pixel array ROIC is the proof of concept of the 10 × 10 pixel array readout ASIC for positron-emission tomography (PET) scanner, positron-emission mammography (PEM) scanner, and Compton gamma camera. The electronics of each individual pixel integrates an analog front-end with switchable gain, an analog to digital converter (ADC), configuration registers, and a 4-state digital controller. For every detected photon, the pixel electronics provides the energy deposited in the detector with 10-bit resolution, and a fast trigger signal for time stamp. The ASIC contains the 16-pixel matrix electronics, a digital controller, five global voltage references, a TDC, a temperature sensor, and a band-gap based current reference. The ASIC has been fabricated with TSMC 0.25 μm mixed-signal CMOS technology and occupies an area of 5.3 mm × 6.8 mm. The TDC shows a resolution of 95.5 ps, a precision of 600 ps at full width half maximum (FWHM), and a power consumption of 130 μW. In acquisition mode, the total power consumption of every pixel is 200 μW. An equivalent noise charge (ENC) of 160 e(-)RMS at maximum gain and negative polarity conditions has been measured at room temperature.

  15. A High-Speed, Event-Driven, Active Pixel Sensor Readout for Photon-Counting Microchannel Plate Detectors

    NASA Technical Reports Server (NTRS)

    Kimble, Randy A.; Pain, Bedabrata; Norton, Timothy J.; Haas, J. Patrick; Oegerle, William R. (Technical Monitor)

    2002-01-01

    Silicon array readouts for microchannel plate intensifiers offer several attractive features. In this class of detector, the electron cloud output of the MCP intensifier is converted to visible light by a phosphor; that light is then fiber-optically coupled to the silicon array. In photon-counting mode, the resulting light splashes on the silicon array are recognized and centroided to fractional pixel accuracy by off-chip electronics. This process can result in very high (MCP-limited) spatial resolution while operating at a modest MCP gain (desirable for dynamic range and long term stability). The principal limitation of intensified CCD systems of this type is their severely limited local dynamic range, as accurate photon counting is achieved only if there are not overlapping event splashes within the frame time of the device. This problem can be ameliorated somewhat by processing events only in pre-selected windows of interest of by using an addressable charge injection device (CID) for the readout array. We are currently pursuing the development of an intriguing alternative readout concept based on using an event-driven CMOS Active Pixel Sensor. APS technology permits the incorporation of discriminator circuitry within each pixel. When coupled with suitable CMOS logic outside the array area, the discriminator circuitry can be used to trigger the readout of small sub-array windows only when and where an event splash has been detected, completely eliminating the local dynamic range problem, while achieving a high global count rate capability and maintaining high spatial resolution. We elaborate on this concept and present our progress toward implementing an event-driven APS readout.

  16. A High-Speed, Event-Driven, Active Pixel Sensor Readout for Photon-Counting Microchannel Plate Detectors

    NASA Technical Reports Server (NTRS)

    Kimble, Randy A.; Pain, B.; Norton, T. J.; Haas, P.; Fisher, Richard R. (Technical Monitor)

    2001-01-01

    Silicon array readouts for microchannel plate intensifiers offer several attractive features. In this class of detector, the electron cloud output of the MCP intensifier is converted to visible light by a phosphor; that light is then fiber-optically coupled to the silicon array. In photon-counting mode, the resulting light splashes on the silicon array are recognized and centroided to fractional pixel accuracy by off-chip electronics. This process can result in very high (MCP-limited) spatial resolution for the readout while operating at a modest MCP gain (desirable for dynamic range and long term stability). The principal limitation of intensified CCD systems of this type is their severely limited local dynamic range, as accurate photon counting is achieved only if there are not overlapping event splashes within the frame time of the device. This problem can be ameliorated somewhat by processing events only in pre-selected windows of interest or by using an addressable charge injection device (CID) for the readout array. We are currently pursuing the development of an intriguing alternative readout concept based on using an event-driven CMOS Active Pixel Sensor. APS technology permits the incorporation of discriminator circuitry within each pixel. When coupled with suitable CMOS logic outside the array area, the discriminator circuitry can be used to trigger the readout of small sub-array windows only when and where an event splash has been detected, completely eliminating the local dynamic range problem, while achieving a high global count rate capability and maintaining high spatial resolution. We elaborate on this concept and present our progress toward implementing an event-driven APS readout.

  17. Backside-illuminated, high-QE, 3e- RoN, fast 700fps, 1760x1680 pixels CMOS imager for AO with highly parallel readout

    NASA Astrophysics Data System (ADS)

    Downing, Mark; Kolb, Johann; Baade, Dietrich; Balard, Philippe; Dierickx, Bart; Defernez, Arnaud; Dupont, Benoit; Feautrier, Philippe; Finger, Gert; Fryer, Martin; Gach, Jean-Luc; Guillaume, Christian; Hubin, Norbert; Iwert, Olaf; Jerram, Paul; Jorden, Paul; Pike, Andrew; Pratlong, Jerome; Reyes, Javier; Stadler, Eric; Walker, Andrew

    2012-07-01

    The success of the next generation of instruments for 8 to 40-m class telescopes will depend upon improving the image quality (correcting the distortion caused by atmospheric turbulence) by exploiting sophisticated Adaptive Optics (AO) systems. One of the critical components of the AO systems for the E-ELT has been identified as the Laser/Natural Guide Star (LGS/NGS) WaveFront Sensing (WFS) detector. The combination of large format, 1760x1680 pixels to finely sample (84x84 sub-apertures) the wavefront and the spot elongation of laser guide stars, fast frame rate of 700 (up to 1000) frames per second, low read noise (< 3e-), and high QE (> 90%) makes the development of such a device extremely challenging. Design studies by industry concluded that a thinned and backside-illuminated CMOS Imager as the most promising technology. This paper describes the multi-phased development plan that will ensure devices are available on-time for E-ELT first-light AO systems; the different CMOS pixel architectures studied; measured results of technology demonstrators that have validated the CMOS Imager approach; the design explaining the approach of massive parallelism (70,000 ADCs) needed to achieve low noise at high pixel rates of ~3 Gpixel/s ; the 88 channel LVDS data interface; the restriction that stitching (required due to the 5x6cm size) posed on the design and the solutions found to overcome these limitations. Two generations of the CMOS Imager will be built: a pioneering quarter sized device of 880x840 pixels capable of meeting first light needs of the E-ELT called NGSD (Natural Guide Star Detector); followed by the full size device, the LGSD (Laser Guide Star Detector). Funding sources: OPTICON FP6 and FP7 from European Commission and ESO.

  18. Pixel CdTe semiconductor module to implement a sub-MeV imaging detector for astrophysics

    NASA Astrophysics Data System (ADS)

    Gálvez, J.-L.; Hernanz, M.; Álvarez, L.; Artigues, B.; Álvarez, J.-M.; Ullán, M.; Pellegrini, G.; Lozano, M.; Cabruja, E.; Martínez, R.; Chmeissani, M.; Puigdengoles, C.

    2017-03-01

    Stellar explosions are relevant and interesting astrophysical phenomena. Since long ago we have been working on the characterization of nova and supernova explosions in X and gamma rays, with the use of space missions such as INTEGRAL, XMM-Newton and Swift. We have been also involved in feasibility studies of future instruments in the energy range from several keV up to a few MeV, in collaboration with other research institutes, such as GRI, DUAL and e-ASTROGAM. High sensitivities are essential to perform detailed studies of cosmic explosions and cosmic accelerators, e.g., Supernovae, Classical Novae, Supernova Remnants (SNRs), Gamma-Ray Bursts (GRBs). In order to fulfil the combined requirement of high detection efficiency with good spatial and energy resolution, an initial module prototype based on CdTe pixel detectors is being developed. The detector dimensions are 12.5mm x 12.5mm x 2mm, with a pixel pitch of 1mm x 1mm. Each pixel is bump bonded to a fanout board made of Sapphire substrate and routed to the corresponding input channel of the readout ASIC, to measure pixel position and pulse height for each incident gamma-ray photon. An ohmic CdTe pixel detector has been characterised by means of 57Co, 133Ba and 22Na sources. Based on this, its spectroscopic performance and the influence of charge sharing is reported here. The pixel study is complemented by the simulation of the CdTe module performance using the GEANT 4 and MEGALIB tools, which will help us to optimise the pixel size selection.

  19. Shape and Albedo from Shading (SAfS) for Pixel-Level dem Generation from Monocular Images Constrained by Low-Resolution dem

    NASA Astrophysics Data System (ADS)

    Wu, Bo; Chung Liu, Wai; Grumpe, Arne; Wöhler, Christian

    2016-06-01

    Lunar topographic information, e.g., lunar DEM (Digital Elevation Model), is very important for lunar exploration missions and scientific research. Lunar DEMs are typically generated from photogrammetric image processing or laser altimetry, of which photogrammetric methods require multiple stereo images of an area. DEMs generated from these methods are usually achieved by various interpolation techniques, leading to interpolation artifacts in the resulting DEM. On the other hand, photometric shape reconstruction, e.g., SfS (Shape from Shading), extensively studied in the field of Computer Vision has been introduced to pixel-level resolution DEM refinement. SfS methods have the ability to reconstruct pixel-wise terrain details that explain a given image of the terrain. If the terrain and its corresponding pixel-wise albedo were to be estimated simultaneously, this is a SAfS (Shape and Albedo from Shading) problem and it will be under-determined without additional information. Previous works show strong statistical regularities in albedo of natural objects, and this is even more logically valid in the case of lunar surface due to its lower surface albedo complexity than the Earth. In this paper we suggest a method that refines a lower-resolution DEM to pixel-level resolution given a monocular image of the coverage with known light source, at the same time we also estimate the corresponding pixel-wise albedo map. We regulate the behaviour of albedo and shape such that the optimized terrain and albedo are the likely solutions that explain the corresponding image. The parameters in the approach are optimized through a kernel-based relaxation framework to gain computational advantages. In this research we experimentally employ the Lunar-Lambertian model for reflectance modelling; the framework of the algorithm is expected to be independent of a specific reflectance model. Experiments are carried out using the monocular images from Lunar Reconnaissance Orbiter (LRO

  20. A Design of a New Column-Parallel Analog-to-Digital Converter Flash for Monolithic Active Pixel Sensor.

    PubMed

    Chakir, Mostafa; Akhamal, Hicham; Qjidaa, Hassan

    2017-01-01

    The CMOS Monolithic Active Pixel Sensor (MAPS) for the International Linear Collider (ILC) vertex detector (VXD) expresses stringent requirements on their analog readout electronics, specifically on the analog-to-digital converter (ADC). This paper concerns designing and optimizing a new architecture of a low power, high speed, and small-area 4-bit column-parallel ADC Flash. Later in this study, we propose to interpose an S/H block in the converter. This integration of S/H block increases the sensitiveness of the converter to the very small amplitude of the input signal from the sensor and provides a sufficient time to the converter to be able to code the input signal. This ADC is developed in 0.18 μm CMOS process with a pixel pitch of 35 μm. The proposed ADC responds to the constraints of power dissipation, size, and speed for the MAPS composed of a matrix of 64 rows and 48 columns where each column ADC covers a small area of 35 × 336.76 μm(2). The proposed ADC consumes low power at a 1.8 V supply and 100 MS/s sampling rate with dynamic range of 125 mV. Its DNL and INL are 0.0812/-0.0787 LSB and 0.0811/-0.0787 LSB, respectively. Furthermore, this ADC achieves a high speed more than 5 GHz.

  1. a Portable Pixel Detector Operating as AN Active Nuclear Emulsion and its Application for X-Ray and Neutron Tomography

    NASA Astrophysics Data System (ADS)

    Vykydal, Z.; Jakubek, J.; Holy, T.; Pospisil, S.

    2006-04-01

    This work is devoted to the development of a USB1.1 (Universal Serial Bus) based read out system for the Medipix2 detector to achieve maximum portability of this position sensitive detecting device. All necessary detector support is integrated into one compact system (80 × 50 × 20 mm3) including the detector bias source (up to 100 V). The read out interface can control external I2C based devices, so in case of tomography it is easy to synchronize detector shutter with stepper motor control. An additional significant advantage of the USB interface is the support of back side pulse processing. This feature enables to determine the energy additionally to the position of a heavy charged particle hitting the sensor. Due to the small pixel dimensions it is also possible to distinguish the type of single quanta of radiation from the track created in the pixel detector as in case of an active nuclear emulsion.

  2. Pixel detector Timepix operated in pile-up mode for pulsed imaging with ultra-soft X-rays

    NASA Astrophysics Data System (ADS)

    Krejci, F.; Jakubek, J.; Kroupa, M.; Bruza, P.; Panek, D.

    2012-12-01

    The hybrid semiconductor pixel detector Timepix operated in the Time-over-Threshold mode (ToT) enables direct energy measurement in each pixel. The advantage of noiseless position sensitive detection combined with per pixel spectroscopic capability opens the way to numerous new applications, which were till now, however, restricted to detection of radiation which is basically above the detector energy threshold (typically 3-4 keV). This limitation excludes application of the hybrid pixel technology to highly interesting fields such as plasma diagnostics or X-ray microscopy. In this contribution we demonstrate how the Timepix detector working in ToT mode can be operated as a detector for particles which are in principle below the detector threshold, namely for soft X-ray photons with energy typically 0.5 keV. The approach is based on the detection of a larger number of photons incoming in the pixel signal processing chain in a time significantly shorter than the shaping time of the pixel electronics, i.e. forming signal pile-up. The proposed approach enables a CCD-like integrating operation with the many advantages of the hybrid counting technology (direct conversion, high sensitivity, dark-current free, room temperature operation, fully digital output and possibility to utilize various read-out architectures). Using the proposed approach we performed single-shot X-ray radiography with a laser-induced plasma source in the spectral region of water window. The same technique was used for the characterization of the source itself.

  3. The wide-field imager for IXO: status and future activities

    NASA Astrophysics Data System (ADS)

    Strüder, Lothar; Aschauer, Florian; Bautz, Mark; Bombelli, Luca; Burrows, David; Fiorini, Carlo; Fraser, George; Herrmann, Sven; Kendziorra, Eckhard; Kuster, Markus; Lauf, Thomas; Lechner, Peter; Lutz, Gerhard; Majewski, Petra; Meuris, Aline; Porro, Matteo; Reiffers, Jonas; Richter, Rainer; Santangelo, Andrea; Soltau, Heike; Stefanescu, Alexander; Tenzer, Chris; Treis, Johannes; Tsunemi, Hiroshi; de Vita, Giulio; Wilms, Jörn

    2010-07-01

    The Wide Field Imager (WFI) of the International X-ray Observatory (IXO) is an X-ray imaging spectrometer based on a large monolithic DePFET (Depleted P-channel Field Effect Transistor) Active Pixel Sensor. Filling an area of 10 x 10 cm2 with a format of 1024 x 1024 pixels it will cover a field of view of 18 arcmin. The pixel size of 100 x 100 μm2 corresponds to a fivefold oversampling of the telescope's expected 5 arcsec point spread function. The WFI's basic DePFET structure combines the functionalities of sensor and integrated amplifier with nearly Fano-limited energy resolution and high efficiency from 100 eV to 15 keV. The development of dedicated control and amplifier ASICs allows for high frame rates up to 1 kHz and flexible readout modes. Results obtained with representative prototypes with a format of 256 x 256 pixels are presented.

  4. Time-resolved Emission from Bright Hot Pixels of an Active Region Observed in the EUV Band with SDO/AIA and Multi-stranded Loop Modeling

    NASA Astrophysics Data System (ADS)

    Tajfirouze, E.; Reale, F.; Petralia, A.; Testa, P.

    2016-01-01

    Evidence of small amounts of very hot plasma has been found in active regions and might be an indication of impulsive heating released at spatial scales smaller than the cross-section of a single loop. We investigate the heating and substructure of coronal loops in the core of one such active region by analyzing the light curves in the smallest resolution elements of solar observations in two EUV channels (94 and 335 Å) from the Atmospheric Imaging Assembly on board the Solar Dynamics Observatory. We model the evolution of a bundle of strands heated by a storm of nanoflares by means of a hydrodynamic 0D loop model (EBTEL). The light curves obtained from a random combination of those of single strands are compared to the observed light curves either in a single pixel or in a row of pixels, simultaneously in the two channels, and using two independent methods: an artificial intelligent system (Probabilistic Neural Network) and a simple cross-correlation technique. We explore the space of the parameters to constrain the distribution of the heat pulses, their duration, their spatial size, and, as a feedback on the data, their signatures on the light curves. From both methods the best agreement is obtained for a relatively large population of events (1000) with a short duration (less than 1 minute) and a relatively shallow distribution (power law with index 1.5) in a limited energy range (1.5 decades). The feedback on the data indicates that bumps in the light curves, especially in the 94 Å channel, are signatures of a heating excess that occurred a few minutes before.

  5. TIME-RESOLVED EMISSION FROM BRIGHT HOT PIXELS OF AN ACTIVE REGION OBSERVED IN THE EUV BAND WITH SDO/AIA AND MULTI-STRANDED LOOP MODELING

    SciTech Connect

    Tajfirouze, E.; Reale, F.; Petralia, A.; Testa, P.

    2016-01-01

    Evidence of small amounts of very hot plasma has been found in active regions and might be an indication of impulsive heating released at spatial scales smaller than the cross-section of a single loop. We investigate the heating and substructure of coronal loops in the core of one such active region by analyzing the light curves in the smallest resolution elements of solar observations in two EUV channels (94 and 335 Å) from the Atmospheric Imaging Assembly on board the Solar Dynamics Observatory. We model the evolution of a bundle of strands heated by a storm of nanoflares by means of a hydrodynamic 0D loop model (EBTEL). The light curves obtained from a random combination of those of single strands are compared to the observed light curves either in a single pixel or in a row of pixels, simultaneously in the two channels, and using two independent methods: an artificial intelligent system (Probabilistic Neural Network) and a simple cross-correlation technique. We explore the space of the parameters to constrain the distribution of the heat pulses, their duration, their spatial size, and, as a feedback on the data, their signatures on the light curves. From both methods the best agreement is obtained for a relatively large population of events (1000) with a short duration (less than 1 minute) and a relatively shallow distribution (power law with index 1.5) in a limited energy range (1.5 decades). The feedback on the data indicates that bumps in the light curves, especially in the 94 Å channel, are signatures of a heating excess that occurred a few minutes before.

  6. A real-time flat-panel X-ray pixel imaging system for low-dose medical diagnostics and craniofacial applications.

    PubMed

    Chapuy, S; Dimcovski, D; Dimcovski, Z; Grigoriev, E; Grob, E; Ligier, Y; Pachoud, M; Riondel, F; Rüfenacht, D; Sayegh, C; Terrier, F; Valley, J F; Verdun, F R

    2000-01-01

    The aim of this study was to evaluate on-line performance of a real-time digital imaging system based on amorphous silicon technology and to compare it with conventional film-screen equipment. The digital detecting imager consists of (1) a converter, which transforms the energy of the incident X rays into light; (2) a real-time digital detecting system, capable of producing as many as 10 pictures per second using a large-area pixel matrix (20 x 20 cm2) based on solid-state amorphous silicon sensor technology with a pitch of 400 microns; and (3) appropriate computer tools for control, real-time image treatment, data representation, and off-line analysis. Different phantoms were used for qualitative comparison with the conventional film-screen technique, with images obtained with both systems at the normal dose (used as a reference), as well as with dose reduction by a factor of 10 to 100. Basic image quality parameters evaluated showed that the response of the detector is linear in a wide range of entrance air kerma; the dynamic range is higher compared with the conventional film-screen combination; the spatial resolution is 1.25 lp per millimeter, as expected from the pixel size; and good image quality is ensured at doses substantially lower than for the film-screen technique. The flat-panel X-ray imager based on amorphous silicon technology implemented in standard radiographic equipment permits acquisition of real-time images in radiology (as many as 10 images per second) of diagnostic quality with a marked reduction of dose (as much as 100 times) and better contrast compared with the standard film technique. Preliminary results obtained with a 100-micron pitch imager based on the same technology show better quality but a less substantial dose reduction. Applications in craniofacial surgery look promising.

  7. Automatic detection and segmentation of vascular structures in dermoscopy images using a novel vesselness measure based on pixel redness and tubularness

    NASA Astrophysics Data System (ADS)

    Kharazmi, Pegah; Lui, Harvey; Stoecker, William V.; Lee, Tim

    2015-03-01

    Vascular structures are one of the most important features in the diagnosis and assessment of skin disorders. The presence and clinical appearance of vascular structures in skin lesions is a discriminating factor among different skin diseases. In this paper, we address the problem of segmentation of vascular patterns in dermoscopy images. Our proposed method is composed of three parts. First, based on biological properties of human skin, we decompose the skin to melanin and hemoglobin component using independent component analysis of skin color images. The relative quantities and pure color densities of each component were then estimated. Subsequently, we obtain three reference vectors of the mean RGB values for normal skin, pigmented skin and blood vessels from the hemoglobin component by averaging over 100000 pixels of each group outlined by an expert. Based on the Euclidean distance thresholding, we generate a mask image that extracts the red regions of the skin. Finally, Frangi measure was applied to the extracted red areas to segment the tubular structures. Finally, Otsu's thresholding was applied to segment the vascular structures and get a binary vessel mask image. The algorithm was implemented on a set of 50 dermoscopy images. In order to evaluate the performance of our method, we have artificially extended some of the existing vessels in our dermoscopy data set and evaluated the performance of the algorithm to segment the newly added vessel pixels. A sensitivity of 95% and specificity of 87% were achieved.

  8. Design methodology: edgeless 3D ASICs with complex in-pixel processing for pixel detectors

    SciTech Connect

    Fahim Farah, Fahim Farah; Deptuch, Grzegorz W.; Hoff, James R.; Mohseni, Hooman

    2015-08-28

    The design methodology for the development of 3D integrated edgeless pixel detectors with in-pixel processing using Electronic Design Automation (EDA) tools is presented. A large area 3 tier 3D detector with one sensor layer and two ASIC layers containing one analog and one digital tier, is built for x-ray photon time of arrival measurement and imaging. A full custom analog pixel is 65μm x 65μm. It is connected to a sensor pixel of the same size on one side, and on the other side it has approximately 40 connections to the digital pixel. A 32 x 32 edgeless array without any peripheral functional blocks constitutes a sub-chip. The sub-chip is an indivisible unit, which is further arranged in a 6 x 6 array to create the entire 1.248cm x 1.248cm ASIC. Each chip has 720 bump-bond I/O connections, on the back of the digital tier to the ceramic PCB. All the analog tier power and biasing is conveyed through the digital tier from the PCB. The assembly has no peripheral functional blocks, and hence the active area extends to the edge of the detector. This was achieved by using a few flavors of almost identical analog pixels (minimal variation in layout) to allow for peripheral biasing blocks to be placed within pixels. The 1024 pixels within a digital sub-chip array have a variety of full custom, semi-custom and automated timing driven functional blocks placed together. The methodology uses a modified mixed-mode on-top digital implementation flow to not only harness the tool efficiency for timing and floor-planning but also to maintain designer control over compact parasitically aware layout. The methodology uses the Cadence design platform, however it is not limited to this tool.

  9. Measurements with MÖNCH, a 25 μm pixel pitch hybrid pixel detector

    NASA Astrophysics Data System (ADS)

    Ramilli, M.; Bergamaschi, A.; Andrae, M.; Brückner, M.; Cartier, S.; Dinapoli, R.; Fröjdh, E.; Greiffenberg, D.; Hutwelker, T.; Lopez-Cuenca, C.; Mezza, D.; Mozzanica, A.; Ruat, M.; Redford, S.; Schmitt, B.; Shi, X.; Tinti, G.; Zhang, J.

    2017-01-01

    MÖNCH is a hybrid silicon pixel detector based on charge integration and with analog readout, featuring a pixel size of 25×25 μm2. The latest working prototype consists of an array of 400×400 identical pixels for a total active area of 1×1 cm2. Its design is optimized for the single photon regime. An exhaustive characterization of this large area prototype has been carried out in the past months, and it confirms an ENC in the order of 35 electrons RMS and a dynamic range of ~4×12 keV photons in high gain mode, which increases to ~100×12 keV photons with the lowest gain setting. The low noise levels of MÖNCH make it a suitable candidate for X-ray detection at energies around 1 keV and below. Imaging applications in particular can benefit significantly from the use of MÖNCH: due to its extremely small pixel pitch, the detector intrinsically offers excellent position resolution. Moreover, in low flux conditions, charge sharing between neighboring pixels allows the use of position interpolation algorithms which grant a resolution at the micrometer-level. Its energy reconstruction and imaging capabilities have been tested for the first time at a low energy beamline at PSI, with photon energies between 1.75 keV and 3.5 keV, and results will be shown.

  10. A Design of a New Column-Parallel Analog-to-Digital Converter Flash for Monolithic Active Pixel Sensor

    PubMed Central

    Qjidaa, Hassan

    2017-01-01

    The CMOS Monolithic Active Pixel Sensor (MAPS) for the International Linear Collider (ILC) vertex detector (VXD) expresses stringent requirements on their analog readout electronics, specifically on the analog-to-digital converter (ADC). This paper concerns designing and optimizing a new architecture of a low power, high speed, and small-area 4-bit column-parallel ADC Flash. Later in this study, we propose to interpose an S/H block in the converter. This integration of S/H block increases the sensitiveness of the converter to the very small amplitude of the input signal from the sensor and provides a sufficient time to the converter to be able to code the input signal. This ADC is developed in 0.18 μm CMOS process with a pixel pitch of 35 μm. The proposed ADC responds to the constraints of power dissipation, size, and speed for the MAPS composed of a matrix of 64 rows and 48 columns where each column ADC covers a small area of 35 × 336.76 μm2. The proposed ADC consumes low power at a 1.8 V supply and 100 MS/s sampling rate with dynamic range of 125 mV. Its DNL and INL are 0.0812/−0.0787 LSB and 0.0811/−0.0787 LSB, respectively. Furthermore, this ADC achieves a high speed more than 5 GHz. PMID:28243628

  11. Pixel color clustering of multi-temporally acquired digital photographs of a rice canopy by luminosity-normalization and pseudo-red-green-blue color imaging.

    PubMed

    Doi, Ryoichi; Arif, Chusnul; Setiawan, Budi Indra; Mizoguchi, Masaru

    2014-01-01

    Red-green-blue (RGB) channels of RGB digital photographs were loaded with luminosity-adjusted R, G, and completely white grayscale images, respectively (RGwhtB method), or R, G, and R + G (RGB yellow) grayscale images, respectively (RGrgbyB method), to adjust the brightness of the entire area of multi-temporally acquired color digital photographs of a rice canopy. From the RGwhtB or RGrgbyB pseudocolor image, cyan, magenta, CMYK yellow, black, L*, a*, and b* grayscale images were prepared. Using these grayscale images and R, G, and RGB yellow grayscale images, the luminosity-adjusted pixels of the canopy photographs were statistically clustered. With the RGrgbyB and the RGwhtB methods, seven and five major color clusters were given, respectively. The RGrgbyB method showed clear differences among three rice growth stages, and the vegetative stage was further divided into two substages. The RGwhtB method could not clearly discriminate between the second vegetative and midseason stages. The relative advantages of the RGrgbyB method were attributed to the R, G, B, magenta, yellow, L*, and a* grayscale images that contained richer information to show the colorimetrical differences among objects than those of the RGwhtB method. The comparison of rice canopy colors at different time points was enabled by the pseudocolor imaging method.

  12. WFC3 Pixel Area Maps

    NASA Astrophysics Data System (ADS)

    Kalirai, J. S.; Cox, C.; Dressel, L.; Fruchter, A.; Hack, W.; Kozhurina-Platais, V.; Mack, J.

    2010-04-01

    We present the pixel area maps (PAMs) for the WFC3/UVIS and WFC3/IR detectors, and discuss the normalization of these images. HST processed flt images suffer from geometric distortion and therefore have pixel areas that vary on the sky. The counts (electrons) measured for a source on these images depends on the position of the source on the detector, an effect that is implicitly corrected when these images are multidrizzled into drz files. The flt images can be multiplied by the PAMs to yield correct and uniform counts for a given source irrespective of its location on the image. To ensure consistency between the count rate measured for sources in drz images and near the center of flt images, we set the normalization of the PAMs to unity at a reference pixel near the center of the UVIS mosaic and IR detector, and set the SCALE in the IDCTAB equal to the square root of the area of this reference pixel. The implications of this choice for photometric measurements are discussed.

  13. High voltage protection in active matrix flat-panel imagers

    NASA Astrophysics Data System (ADS)

    Lehnert, Joerg; Zhao, Wei

    2006-03-01

    Various direct and indirect active matrix flat-panel imagers (AMFPI) are being investigated for x-ray imaging. In both direct AMFPI and indirect AMFPI with avalanche gain, a bias potential up to several thousand volts is required to operate the photoconductor. Under the condition of a large amount of radiation exposure between subsequent readout, a potential >80 V could appear across the amorphous silicon (a-Si) thin film transistor (TFT) and cause permanent damage. The purpose of this paper is to investigate a simple pixel design for high voltage protection. The pixel electrode acts as an additional gate for the top channel of an a-Si TFT to drain excess image charge from the pixel electrode until an equilibrium is reached where the TFT channel current equals the detector signal current at a predetermined safe maximum value V Pmax for the pixel potential. This "dual-gate" TFT structure without additional protective device simplifies the TFT array design and improves yield. However special care is required to understand the characteristics of both the top and the bottom gates to ensure sufficient detector dynamic range as well as reliable high voltage protection. A physical model for dual-gate a-Si TFTs was developed and device parameters were determined by fitting the model to measured characteristics from a dual-gate TFT array. Our results showed that compared to the bottom (normal) gate, the protective gate has a shallower transfer characteristics (i.e. channel current as a function of gate voltage) due to a higher density of states in the top interface. Nevertheless it provides adequate protection of the TFT with V Pmax of ~40 V for typical radiographic exposures.

  14. Combinational pixel-by-pixel and object-level classifying, segmenting, and agglomerating in performing quantitative image analysis that distinguishes between healthy non-cancerous and cancerous cell nuclei and delineates nuclear, cytoplasm, and stromal material objects from stained biological tissue materials

    DOEpatents

    Boucheron, Laura E

    2013-07-16

    Quantitative object and spatial arrangement-level analysis of tissue are detailed using expert (pathologist) input to guide the classification process. A two-step method is disclosed for imaging tissue, by classifying one or more biological materials, e.g. nuclei, cytoplasm, and stroma, in the tissue into one or more identified classes on a pixel-by-pixel basis, and segmenting the identified classes to agglomerate one or more sets of identified pixels into segmented regions. Typically, the one or more biological materials comprises nuclear material, cytoplasm material, and stromal material. The method further allows a user to markup the image subsequent to the classification to re-classify said materials. The markup is performed via a graphic user interface to edit designated regions in the image.

  15. Active Imaging through Cirrus Clouds.

    PubMed

    Landesman, B; Kindilien, P; Pierson, R; Matson, C; Mosley, D

    1997-11-24

    The presence of clouds of ice particles in the uplink and downlink path of an illumination beam can severely impede the performance of an active imaging system. Depending on the optical depth of the cloud, i.e., its density and depth, the beam can be completely scattered and extinguished, or the beam can pass through the cloud with some fraction attenuated, scattered, and depolarized. In particular, subvisual cirrus clouds, i.e., high, thin cirrus clouds that cannot be observed from the ground, can affect the properties and alignment of both uplink and downlink beams. This paper discusses the potential for active imaging in the presence of cirrus clouds. We document field data results from an active imaging experiment conducted several years ago, which the authors believe to show the effects of cirrus clouds on an active imaging system. To verify these conclusions, we include the results of a simulation of the interaction of a coherent illumination scheme with a cirrus cloud.

  16. Pixel Analysis and Plasma Dynamics Characterized by Photospheric Spectral Data

    NASA Astrophysics Data System (ADS)

    Rasca, A.; Chen, J.; Pevtsov, A. A.

    2015-12-01

    Continued advances in solar observations have led to higher-resolution magnetograms and surface (photospheric) images, revealing bipolar magnetic features operating near the resolution limit during emerging flux events and other phenomena used to predict solar eruptions responsible for geomagnetic plasma disturbances. However, line of sight (LOS) magnetogram pixels only contain the net uncanceled magnetic flux, which is expected to increase for fixed regions as resolution limits improve. A pixel dynamics model utilizing Stokes I spectral profiles was previously-used to quantify changes in the Doppler shift, width, asymmetry, and tail flatness of Fe I lines at 6301.5 and 6302.5 Å and used pixel-by-pixel line profile fluctuations to characterize quiet and active regions on the Sun. We use this pixel dynamics model with circularly polarized photospheric data (e.g., SOLIS data) to estimate plasma dynamic properties at a sub-pixel level. The analysis can be extended to include the full Stokes parameters and study signatures of magnetic fields and coupled plasma properties on sub-pixel scales.

  17. A 128×96 Pixel Stack-Type Color Image Sensor: Stack of Individual Blue-, Green-, and Red-Sensitive Organic Photoconductive Films Integrated with a ZnO Thin Film Transistor Readout Circuit

    NASA Astrophysics Data System (ADS)

    Seo, Hokuto; Aihara, Satoshi; Watabe, Toshihisa; Ohtake, Hiroshi; Sakai, Toshikatsu; Kubota, Misao; Egami, Norifumi; Hiramatsu, Takahiro; Matsuda, Tokiyoshi; Furuta, Mamoru; Hirao, Takashi

    2011-02-01

    A color image was produced by a vertically stacked image sensor with blue (B)-, green (G)-, and red (R)-sensitive organic photoconductive films, each having a thin-film transistor (TFT) array that uses a zinc oxide (ZnO) channel to read out the signal generated in each organic film. The number of the pixels of the fabricated image sensor is 128×96 for each color, and the pixel size is 100×100 µm2. The current on/off ratio of the ZnO TFT is over 106, and the B-, G-, and R-sensitive organic photoconductive films show excellent wavelength selectivity. The stacked image sensor can produce a color image at 10 frames per second with a resolution corresponding to the pixel number. This result clearly shows that color separation is achieved without using any conventional color separation optical system such as a color filter array or a prism.

  18. Measurement of 3-D Vibrational Motion by Dynamic Photogrammetry Using Least-Square Image Matching for Sub-Pixel Targeting to Improve Accuracy.

    PubMed

    Lee, Hyoseong; Rhee, Huinam; Oh, Jae Hong; Park, Jin Ho

    2016-03-11

    This paper deals with an improved methodology to measure three-dimensional dynamic displacements of a structure by digital close-range photogrammetry. A series of stereo images of a vibrating structure installed with targets are taken at specified intervals by using two daily-use cameras. A new methodology is proposed to accurately trace the spatial displacement of each target in three-dimensional space. This method combines the correlation and the least-square image matching so that the sub-pixel targeting can be obtained to increase the measurement accuracy. Collinearity and space resection theory are used to determine the interior and exterior orientation parameters. To verify the proposed method, experiments have been performed to measure displacements of a cantilevered beam excited by an electrodynamic shaker, which is vibrating in a complex configuration with mixed bending and torsional motions simultaneously with multiple frequencies. The results by the present method showed good agreement with the measurement by two laser displacement sensors. The proposed methodology only requires inexpensive daily-use cameras, and can remotely detect the dynamic displacement of a structure vibrating in a complex three-dimensional defection shape up to sub-pixel accuracy. It has abundant potential applications to various fields, e.g., remote vibration monitoring of an inaccessible or dangerous facility.

  19. Measurement of 3-D Vibrational Motion by Dynamic Photogrammetry Using Least-Square Image Matching for Sub-Pixel Targeting to Improve Accuracy

    PubMed Central

    Lee, Hyoseong; Rhee, Huinam; Oh, Jae Hong; Park, Jin Ho

    2016-01-01

    This paper deals with an improved methodology to measure three-dimensional dynamic displacements of a structure by digital close-range photogrammetry. A series of stereo images of a vibrating structure installed with targets are taken at specified intervals by using two daily-use cameras. A new methodology is proposed to accurately trace the spatial displacement of each target in three-dimensional space. This method combines the correlation and the least-square image matching so that the sub-pixel targeting can be obtained to increase the measurement accuracy. Collinearity and space resection theory are used to determine the interior and exterior orientation parameters. To verify the proposed method, experiments have been performed to measure displacements of a cantilevered beam excited by an electrodynamic shaker, which is vibrating in a complex configuration with mixed bending and torsional motions simultaneously with multiple frequencies. The results by the present method showed good agreement with the measurement by two laser displacement sensors. The proposed methodology only requires inexpensive daily-use cameras, and can remotely detect the dynamic displacement of a structure vibrating in a complex three-dimensional defection shape up to sub-pixel accuracy. It has abundant potential applications to various fields, e.g., remote vibration monitoring of an inaccessible or dangerous facility. PMID:26978366

  20. Active spectral imaging and mapping

    NASA Astrophysics Data System (ADS)

    Steinvall, Ove

    2014-04-01

    Active imaging and mapping using lasers as illumination sources have been of increasing interest during the last decades. Applications range from defense and security, remote sensing, medicine, robotics, and others. So far, these laser systems have mostly been based on a fix wavelength laser. Recent advances in lasers enable emission of tunable, multiline, or broadband emission, which together with the development of array detectors will extend the capabilities of active imaging and mapping. This paper will review some of the recent work on active imaging mainly for defense and security and remote sensing applications. A short survey of basic lidar relations and present fix wavelength laser systems is followed by a review of the benefits of adding the spectral dimension to active and/or passive electro-optical systems.

  1. Imaging nervous system activity.

    PubMed

    Fields, Douglas R; Shneider, Neil; Mentis, George Z; O'Donovan, Michael J

    2009-10-01

    This unit describes methods for loading ion- and voltage-sensitive dyes into neurons, with a particular focus on the spinal cord as a model system. In addition, we describe the use of these dyes to visualize neural activity. Although the protocols described here concern spinal networks in culture or an intact in vitro preparation, they can be, and have been, widely used in other parts of the nervous system.

  2. The ALICE Pixel Detector

    NASA Astrophysics Data System (ADS)

    Mercado-Perez, Jorge

    2002-07-01

    The present document is a brief summary of the performed activities during the 2001 Summer Student Programme at CERN under the Scientific Summer at Foreign Laboratories Program organized by the Particles and Fields Division of the Mexican Physical Society (Sociedad Mexicana de Fisica). In this case, the activities were related with the ALICE Pixel Group of the EP-AIT Division, under the supervision of Jeroen van Hunen, research fellow in this group. First, I give an introduction and overview to the ALICE experiment; followed by a description of wafer probing. A brief summary of the test beam that we had from July 13th to July 25th is given as well.

  3. Localized Patch-Based Fuzzy Active Contours for Image Segmentation

    PubMed Central

    Liu, Huaxiang; Zhang, Liting; Liu, Jun

    2016-01-01

    This paper presents a novel fuzzy region-based active contour model for image segmentation. By incorporating local patch-energy functional along each pixel of the evolving curve into the fuzziness of the energy, we construct a patch-based energy function without the regurgitation term. Its purpose is not only to make the active contour evolve very stably without the periodical initialization during the evolution but also to reduce the effect of noise. In particular, in order to reject local minimal of the energy functional, we utilize a direct method to calculate the energy alterations instead of solving the Euler-Lagrange equation of the underlying problem. Compared with other fuzzy active contour models, experimental results on synthetic and real images show the advantages of the proposed method in terms of computational efficiency and accuracy. PMID:28070210

  4. CMOS foveal image sensor chip

    NASA Technical Reports Server (NTRS)

    Bandera, Cesar (Inventor); Scott, Peter (Inventor); Sridhar, Ramalingam (Inventor); Xia, Shu (Inventor)

    2002-01-01

    A foveal image sensor integrated circuit comprising a plurality of CMOS active pixel sensors arranged both within and about a central fovea region of the chip. The pixels in the central fovea region have a smaller size than the pixels arranged in peripheral rings about the central region. A new photocharge normalization scheme and associated circuitry normalizes the output signals from the different size pixels in the array. The pixels are assembled into a multi-resolution rectilinear foveal image sensor chip using a novel access scheme to reduce the number of analog RAM cells needed. Localized spatial resolution declines monotonically with offset from the imager's optical axis, analogous to biological foveal vision.

  5. Dead pixel replacement in LWIR microgrid polarimeters.

    PubMed

    Ratliff, Bradley M; Tyo, J Scott; Boger, James K; Black, Wiley T; Bowers, David L; Fetrow, Matthew P

    2007-06-11

    LWIR imaging arrays are often affected by nonresponsive pixels, or "dead pixels." These dead pixels can severely degrade the quality of imagery and often have to be replaced before subsequent image processing and display of the imagery data. For LWIR arrays that are integrated with arrays of micropolarizers, the problem of dead pixels is amplified. Conventional dead pixel replacement (DPR) strategies cannot be employed since neighboring pixels are of different polarizations. In this paper we present two DPR schemes. The first is a modified nearest-neighbor replacement method. The second is a method based on redundancy in the polarization measurements.We find that the redundancy-based DPR scheme provides an order-of-magnitude better performance for typical LWIR polarimetric data.

  6. MediSPECT: Single photon emission computed tomography system for small field of view small animal imaging based on a CdTe hybrid pixel detector

    NASA Astrophysics Data System (ADS)

    Accorsi, R.; Autiero, M.; Celentano, L.; Chmeissani, M.; Cozzolino, R.; Curion, A. S.; Frallicciardi, P.; Laccetti, P.; Lanza, R. C.; Lauria, A.; Maiorino, M.; Marotta, M.; Mettivier, G.; Montesi, M. C.; Riccio, P.; Roberti, G.; Russo, P.

    2007-02-01

    We describe MediSPECT, a new scanner developed at University and INFN Napoli, for SPECT studies on small animals with a small field of view (FOV) and high spatial resolution. The CdTe pixel detector (a 256×256 matrix of 55 μm square pixels) operating in single photon counting for detection of gamma-rays with low and medium energy (e.g. 125I, 27-35 keV, 99mTc, 140 keV), is bump bonded to the Medipix2 readout chip. The FOV of the MediSPECT scanner with a coded aperture mask collimator ranges from 6.3 mm (system spatial resolution 110 μm at 27-35 keV) to 24.3 mm. With a 0.30 mm pinhole the FOV ranges from 2.4 to 29 mm (where the system spatial resolution is 1.0 mm at 27-35 keV and 2.0 mm at 140 keV). MediSPECT will be used for in vivo imaging of small organs or tissue structures in mouse, e.g., brain, thyroid, heart or tumor.

  7. New CMOS digital pixel sensor architecture dedicated to a visual cortical implant

    NASA Astrophysics Data System (ADS)

    Trépanier, Annie; Trépanier, Jean-Luc; Sawan, Mohamad; Audet, Yves

    2004-10-01

    A CMOS image sensor with pixel level analog to digital conversion is presented. Each 16μm x 16μm pixel area contains a photodiode, with a fill factor of 22%, a comparator and an 8-bit DRAM, resulting in a total of 44 transistors per pixel. A digital to analog converter is used to deliver a voltage reference to compare with the pixel voltage for the analog to digital conversion. This sensor is required by a visual cortical stimulator, primarily to capture the image which is dedicated to stimulate the visual cortex of a blind patient. An active range finder system will be added to the implant, requiring the difference information between two images, in order to obtain the 3D information useful to the patient. For this purpose, three selectable operation modes are combined in the same pixel circuit. The linear integration, resulting from image capture at multiple exposure times, allows a high intrascene dynamic range. Random accessibility, in space and time, of the array of sensors is possible with the logarithmic mode. And the new differential mode makes the difference between two consecutive images. The circuit of a pixel has been fabricated in CMOS 0.18μm technology and it is under test to validate the full operation of the 3 modes. Also, a matrix of 45 x 90 pixels is currently being implemented for fabrication.

  8. Evaluation of list-mode ordered subset expectation maximization image reconstruction for pixelated solid-state compton gamma camera with large number of channels

    NASA Astrophysics Data System (ADS)

    Kolstein, M.; De Lorenzo, G.; Chmeissani, M.

    2014-04-01

    The Voxel Imaging PET (VIP) Pathfinder project intends to show the advantages of using pixelated solid-state technology for nuclear medicine applications. It proposes designs for Positron Emission Tomography (PET), Positron Emission Mammography (PEM) and Compton gamma camera detectors with a large number of signal channels (of the order of 106). For Compton camera, especially with a large number of readout channels, image reconstruction presents a big challenge. In this work, results are presented for the List-Mode Ordered Subset Expectation Maximization (LM-OSEM) image reconstruction algorithm on simulated data with the VIP Compton camera design. For the simulation, all realistic contributions to the spatial resolution are taken into account, including the Doppler broadening effect. The results show that even with a straightforward implementation of LM-OSEM, good images can be obtained for the proposed Compton camera design. Results are shown for various phantoms, including extended sources and with a distance between the field of view and the first detector plane equal to 100 mm which corresponds to a realistic nuclear medicine environment.

  9. Improving spatio-temporal resolution of infrared images to detect thermal activity of defect at the surface of inorganic glass

    NASA Astrophysics Data System (ADS)

    Corvec, Guillaume; Robin, Eric; Le Cam, Jean-Benoît; Sangleboeuf, Jean-Christophe; Lucas, Pierre

    2016-07-01

    This paper proposes a noise suppression methodology to improve the spatio-temporal resolution of infrared images. The methodology is divided in two steps. The first one consists in removing the noise from the temporal signal at each pixel. Three basic temporal filters are considered for this purpose: average filter, cost function minimization (FIT) and short time Fast Fourier Transform approach (STFFT). But while this step effectively reduces the temporal signal noise at each pixel, the infrared images may still appear noisy. This is due to a random distribution of a residual offset value of pixels signal. Hence in the second step, the residual offset is identified by considering thermal images for which no mechanical loading is applied. In this case, the temperature variation field is homogeneous and the value of temperature variation at each pixel is theoretically equal to zero. The method is first tested on synthetic images built from infrared computer-generated images combined with experimental noise. The results demonstrate that this approach permits to keep the spatial resolution of infrared images equal to 1 pixel. The methodology is then applied to characterize thermal activity of a defect at the surface of inorganic glass submitted to cyclic mechanical loading. The three basic temporal filters are quantitatively compared and contrasted. Results obtained demonstrate that, contrarily to a basic spatio-temporal approach, the denoising method proposed is suitable to characterize low thermal activity combined to strong spatial gradients induced by cyclic heterogeneous deformations.

  10. Modulation transfer function of a trapezoidal pixel array detector

    NASA Astrophysics Data System (ADS)

    Wang, Fan; Guo, Rongli; Ni, Jinping; Dong, Tao

    2016-01-01

    The modulation transfer function (MTF) is the tool most commonly used for quantifying the performance of an electro-optical imaging system. Recently, trapezoid-shaped pixels were designed and used in a retina-like sensor in place of rectangular-shaped pixels. The MTF of a detector with a trapezoidal pixel array is determined according to its definition. Additionally, the MTFs of detectors with differently shaped pixels, but the same pixel areas, are compared. The results show that the MTF values of the trapezoidal pixel array detector are obviously larger than those of rectangular and triangular pixel array detectors at the same frequencies.

  11. Local Pixel Bundles: Bringing the Pixels to the People

    NASA Astrophysics Data System (ADS)

    Anderson, Jay

    2014-12-01

    The automated galaxy-based alignment software package developed for the Frontier Fields program (hst2galign, see Anderson & Ogaz 2014 and http://www.stsci.edu/hst/campaigns/frontier-fields/) produces a direct mapping from the pixels of the flt frame of each science exposure into a common master frame. We can use these mappings to extract the flt-pixels in the vicinity of a source of interest and package them into a convenient "bundle". In addition to the pixels, this data bundle can also contain "meta" information that will allow users to transform positions from the flt pixels to the reference frame and vice-versa. Since the un-resampled pixels in the flt frames are the only true constraints we have on the astronomical scene, the ability to inter-relate these pixels will enable many high-precision studies, such as: point-source-fitting and deconvolution with accurate PSFs, easy exploration of different image-combining algorithms, and accurate faint-source finding and photometry. The data products introduced in this ISR are a very early attempt to provide the flt-level pixel constraints in a package that is accessible to more than the handful of experts in HST astrometry. The hope is that users in the community might begin using them and will provide feedback as to what information they might want to see in the bundles and what general analysis packages they might find useful. For that reason, this document is somewhat informally written, since I know that it will be modified and updated as the products and tools are optimized.

  12. A 190GHz active millimeter-wave imager

    NASA Astrophysics Data System (ADS)

    Brothers, Michael L.; Timms, Greg P.; Bunton, John D.; Archer, John W.; Tello, Juan Y.; Rosolen, Grahame C.; Li, Yue; Hellicar, Andrew D.

    2007-04-01

    The design and testing of a 190 GHz imaging system is presented. The system features two beam-scanning antennas; the first transmits a horizontal fan beam and the second receives a vertical fan beam. By correlating the signals from the antennas, an estimate of the millimeter-wave reflectivity at the intersection of the fan beams is obtained. Each fan beam is scanned by rotating a small subreflector within the antenna; this simple rotation motion allows rapid scanning. The system is portable, currently approximately 0.6m × 0.6m × 2m high; the key size constraint is imposed by the 450 mm aperture length of the antennas. The imager has an angular resolution of 0.25° and a field of view of 14°×14°, resulting in a raw image of approximately 50 × 50 pixels. The raw image is processed using super-resolution techniques. Images will be presented which show the capability of the system to image metallic and ceramic objects beneath clothing. These images were obtained by illuminating the scene with signals from a frequency-doubled Gunn oscillator. While this paper focuses on active imaging, the system can also operate in passive mode with reduced sensitivity.

  13. Adaptive bad pixel correction algorithm for IRFPA based on PCNN

    NASA Astrophysics Data System (ADS)

    Leng, Hanbing; Zhou, Zuofeng; Cao, Jianzhong; Yi, Bo; Yan, Aqi; Zhang, Jian

    2013-10-01

    Bad pixels and response non-uniformity are the primary obstacles when IRFPA is used in different thermal imaging systems. The bad pixels of IRFPA include fixed bad pixels and random bad pixels. The former is caused by material or manufacture defect and their positions are always fixed, the latter is caused by temperature drift and their positions are always changing. Traditional radiometric calibration-based bad pixel detection and compensation algorithm is only valid to the fixed bad pixels. Scene-based bad pixel correction algorithm is the effective way to eliminate these two kinds of bad pixels. Currently, the most used scene-based bad pixel correction algorithm is based on adaptive median filter (AMF). In this algorithm, bad pixels are regarded as image noise and then be replaced by filtered value. However, missed correction and false correction often happens when AMF is used to handle complex infrared scenes. To solve this problem, a new adaptive bad pixel correction algorithm based on pulse coupled neural networks (PCNN) is proposed. Potential bad pixels are detected by PCNN in the first step, then image sequences are used periodically to confirm the real bad pixels and exclude the false one, finally bad pixels are replaced by the filtered result. With the real infrared images obtained from a camera, the experiment results show the effectiveness of the proposed algorithm.

  14. Pixel multiplexing technique for real-time three-dimensional-imaging laser detection and ranging system using four linear-mode avalanche photodiodes

    NASA Astrophysics Data System (ADS)

    Xu, Fan; Wang, Yuanqing; Li, Fenfang

    2016-03-01

    The avalanche-photodiode-array (APD-array) laser detection and ranging (LADAR) system has been continually developed owing to its superiority of nonscanning, large field of view, high sensitivity, and high precision. However, how to achieve higher-efficient detection and better integration of the LADAR system for real-time three-dimensional (3D) imaging continues to be a problem. In this study, a novel LADAR system using four linear mode APDs (LmAPDs) is developed for high-efficient detection by adopting a modulation and multiplexing technique. Furthermore, an automatic control system for the array LADAR system is proposed and designed by applying the virtual instrumentation technique. The control system aims to achieve four functions: synchronization of laser emission and rotating platform, multi-channel synchronous data acquisition, real-time Ethernet upper monitoring, and real-time signal processing and 3D visualization. The structure and principle of the complete system are described in the paper. The experimental results demonstrate that the LADAR system is capable of achieving real-time 3D imaging on an omnidirectional rotating platform under the control of the virtual instrumentation system. The automatic imaging LADAR system utilized only 4 LmAPDs to achieve 256-pixel-per-frame detection with by employing 64-bit demodulator. Moreover, the lateral resolution is ˜15 cm and range accuracy is ˜4 cm root-mean-square error at a distance of ˜40 m.

  15. Low-Voltage 96 dB Snapshot CMOS Image Sensor with 4.5 nW Power Dissipation per Pixel

    PubMed Central

    Spivak, Arthur; Teman, Adam; Belenky, Alexander; Yadid-Pecht, Orly; Fish, Alexander

    2012-01-01

    Modern “smart” CMOS sensors have penetrated into various applications, such as surveillance systems, bio-medical applications, digital cameras, cellular phones and many others. Reducing the power of these sensors continuously challenges designers. In this paper, a low power global shutter CMOS image sensor with Wide Dynamic Range (WDR) ability is presented. This sensor features several power reduction techniques, including a dual voltage supply, a selective power down, transistors with different threshold voltages, a non-rationed logic, and a low voltage static memory. A combination of all these approaches has enabled the design of the low voltage “smart” image sensor, which is capable of reaching a remarkable dynamic range, while consuming very low power. The proposed power-saving solutions have allowed the maintenance of the standard architecture of the sensor, reducing both the time and the cost of the design. In order to maintain the image quality, a relation between the sensor performance and power has been analyzed and a mathematical model, describing the sensor Signal to Noise Ratio (SNR) and Dynamic Range (DR) as a function of the power supplies, is proposed. The described sensor was implemented in a 0.18 um CMOS process and successfully tested in the laboratory. An SNR of 48 dB and DR of 96 dB were achieved with a power dissipation of 4.5 nW per pixel. PMID:23112588

  16. High-flux ptychographic imaging using the new 55 µm-pixel detector ‘Lambda’ based on the Medipix3 readout chip

    SciTech Connect

    Wilke, R. N. Wallentin, J.; Osterhoff, M.; Pennicard, D.; Zozulya, A.; Sprung, M.; Salditt, T.

    2014-11-01

    The Large Area Medipix-Based Detector Array (Lambda) has been used in a ptychographic imaging experiment on solar-cell nanowires. By using a semi-transparent central stop, the high flux density provided by nano-focusing Kirkpatrick–Baez mirrors can be fully exploited for high-resolution phase reconstructions. Suitable detection systems that are capable of recording high photon count rates with single-photon detection are instrumental for coherent X-ray imaging. The new single-photon-counting pixel detector ‘Lambda’ has been tested in a ptychographic imaging experiment on solar-cell nanowires using Kirkpatrick–Baez-focused 13.8 keV X-rays. Taking advantage of the high count rate of the Lambda and dynamic range expansion by the semi-transparent central stop, a high-dynamic-range diffraction signal covering more than seven orders of magnitude has been recorded, which corresponds to a photon flux density of about 10{sup 5} photons nm{sup −2} s{sup −1} or a flux of ∼10{sup 10} photons s{sup −1} on the sample. By comparison with data taken without the semi-transparent central stop, an increase in resolution by a factor of 3–4 is determined: from about 125 nm to about 38 nm for the nanowire and from about 83 nm to about 21 nm for the illuminating wavefield.

  17. Phase unwrapping in spectral X-ray differential phase-contrast imaging with an energy-resolving photon-counting pixel detector.

    PubMed

    Epple, Franz M; Ehn, Sebastian; Thibault, Pierre; Koehler, Thomas; Potdevin, Guillaume; Herzen, Julia; Pennicard, David; Graafsma, Heinz; Noël, Peter B; Pfeiffer, Franz

    2015-03-01

    Grating-based differential phase-contrast imaging has proven to be feasible with conventional X-ray sources. The polychromatic spectrum generally limits the performance of the interferometer but benefit can be gained with an energy-sensitive detector. In the presented work, we employ the energy-discrimination capability to correct for phase-wrapping artefacts. We propose to use the phase shifts, which are measured in distinct energy bins, to estimate the optimal phase shift in the sense of maximum likelihood. We demonstrate that our method is able to correct for phase-wrapping artefacts, to improve the contrast-to-noise ratio and to reduce beam hardening due to the modelled energy dependency. The method is evaluated on experimental data which are measured with a laboratory Talbot-Lau interferometer equipped with a conventional polychromatic X-ray source and an energy-sensitive photon-counting pixel detector. Our work shows, that spectral imaging is an important step to move differential phase-contrast imaging closer to pre-clinical and clinical applications, where phase wrapping is particularly problematic.

  18. Dynamically re-configurable CMOS imagers for an active vision system

    NASA Technical Reports Server (NTRS)

    Yang, Guang (Inventor); Pain, Bedabrata (Inventor)

    2005-01-01

    A vision system is disclosed. The system includes a pixel array, at least one multi-resolution window operation circuit, and a pixel averaging circuit. The pixel array has an array of pixels configured to receive light signals from an image having at least one tracking target. The multi-resolution window operation circuits are configured to process the image. Each of the multi-resolution window operation circuits processes each tracking target within a particular multi-resolution window. The pixel averaging circuit is configured to sample and average pixels within the particular multi-resolution window.

  19. Determining object boundaries from MR images with sub-pixel resolution: Towards in-line inspection with a mobile tomograph

    NASA Astrophysics Data System (ADS)

    Danieli, Ernesto; Berdel, Klaus; Perlo, Juan; Michaeli, Walter; Masberg, Ullrich; Blümich, Bernhard; Casanova, Federico

    2010-11-01

    This work evaluates the performance of edge-detection algorithms to determine the sample geometry with high spatial accuracy from low-resolution MR images. In particular, we show that by applying such numerical methods it is possible to reconstruct the internal and external contours of the object with a spatial precision that surpasses the nominal spatial resolution of the image by more than one order of magnitude. Special attention is paid to find the spatial resolution and signal-to-noise ratio required by the described numerical methodology to achieve a desired spatial accuracy. Finally, we discuss the potential application of this image processing approach for in-line quality control of extruded rubber materials, where micrometer spatial precision has to be achieved from images measured in short experimental times. The results presented here prove that the sensitivity of mobile MRI sensors is enough to achieve the spatial accuracy required to proof check the production of extruded rubber fittings in acceptable experimental times.

  20. Pixel Analysis of Photospheric Spectral Data. I. Plasma Dynamics

    NASA Astrophysics Data System (ADS)

    Rasca, Anthony P.; Chen, James; Pevtsov, Alexei A.

    2016-11-01

    Recent observations of the photosphere using high spatial and temporal resolution show small dynamic features at or below the current resolving limits. A new pixel dynamics method has been developed to analyze spectral profiles and quantify changes in line displacement, width, asymmetry, and peakedness of photospheric absorption lines. The algorithm evaluates variations of line profile properties in each pixel and determines the statistics of such fluctuations averaged over all pixels in a given region. The method has been used to derive statistical characteristics of pixel fluctuations in observed quiet-Sun regions, an active region with no eruption, and an active region with an ongoing eruption. Using Stokes I images from the Vector Spectromagnetograph (VSM) of the Synoptic Optical Long-term Investigations of the Sun (SOLIS) telescope on 2012 March 13, variations in line width and peakedness of Fe i 6301.5 Å are shown to have a distinct spatial and temporal relationship with an M7.9 X-ray flare in NOAA 11429. This relationship is observed as stationary and contiguous patches of pixels adjacent to a sunspot exhibiting intense flattening in the line profile and line-center displacement as the X-ray flare approaches peak intensity, which is not present in area scans of the non-eruptive active region. The analysis of pixel dynamics allows one to extract quantitative information on differences in plasma dynamics on sub-pixel scales in these photospheric regions. The analysis can be extended to include the Stokes parameters and study signatures of vector components of magnetic fields and coupled plasma properties.

  1. Relative dosimetry using active matrix flat-panel imager (AMFPI) technology.

    PubMed

    El-Mohri, Y; Antonuk, L E; Yorkston, J; Jee, K W; Maolinbay, M; Lam, K L; Siewerdsen, J H

    1999-08-01

    The first examination of the use of active matrix flat-panel arrays for dosimetry in radiotherapy is reported. Such arrays are under widespread development for diagnostic and radiotherapy imaging. In the current study, an array consisting of 512 x 512 pixels with a pixel pitch of 508 microm giving an area of 26 x 26 cm2 has been used. Each pixel consists of a light sensitive amorphous silicon (a-Si:H) photodiode coupled to an a-Si:H thin-film transistor. Data was obtained from the array using a dedicated electronics system allowing real-time data acquisition. In order to examine the potential of such arrays as quality assurance devices for radiotherapy beams, field profile data at photon energies of 6 and 15 MV were obtained as a function of field size and thickness of overlying absorbing material (solid water). Two detection configurations using the array were considered: a configuration (similar to the imaging configuration) in which an overlying phosphor screen is used to convert incident radiation to visible light photons which are detected by the photodiodes; and a configuration without the screen where radiation is directly sensed by the photodiodes. Compared to relative dosimetry data obtained with an ion chamber, data taken using the former configuration exhibited significant differences whereas data obtained using the latter configuration was generally found to be in close agreement. Basic signal properties, which are pertinent to dosimetry, have been investigated through measurements of individual pixel response for fluoroscopic and radiographic array operation. For signal levels acquired within the first 25% of pixel charge capacity, the degree of linear response with dose was found to be better than 99%. The independence of signal on dose rate was demonstrated by means of stability of pixel response over the range of dose rates allowed by the radiation source (80-400 MU/min). Finally, excellent long-term stability in pixel response, extending over a 2

  2. Source Driver Channel Reduction Schemes Employing Corresponding Pixel Alignments for Current Programming Active-Matrix Organic Light-Emitting Diode Displays

    NASA Astrophysics Data System (ADS)

    Hong, Soon-Kwang; Oh, Du-Hwan; Jeong, Seok-Hee; Park, Young-Ju; Kim, Byeong-Koo; Ha, Yong-Min; Jang, Jin

    2008-03-01

    We propose two types of novel scheme for reducing the number of output channels of driver-integrated circuit (D-IC) for the current programming compensation pixel structures of active-matrix organic light-emitting diodes (AMOLEDs). One is a 2:1 data demultiplexing technique that can reduce the number of output channels of D-IC by half. The proposed second scheme is a vertically aligned red (R), green (G), and blue (B) subpixel scheme instead of a horizontally aligned R-G-B subpixel one, which is regarded as the conventional pixel alignment scheme. We have also successfully implemented these schemes in a 2.4-in.-sized QCIF + (176 × RGB × 220) AMOLED using p-type excimer laser annealing (ELA) low-temperature polycrystalline silicon (LTPS) technology and evaluated key performance characteristics.

  3. Pixel Analysis and Plasma Dynamics Characterized by Photospheric Spectral Data

    NASA Astrophysics Data System (ADS)

    Rasca, Anthony P.; Chen, James; Pevtsov, Alexei A.

    2016-05-01

    Recent observations of the photosphere using high spatial and temporal resolutions show small dynamic features at the resolving limit during emerging flux events. However, line-of-sight (LOS) magnetogram pixels only contain the net uncanceled magnetic flux, which is expected to increase for fixed regions as resolution limits improve. A new pixel dynamics method uses spectrographic images to characterize photospheric absorption line profiles by variations in line displacement, width, asymmetry, and peakedness and is applied to quiet-sun regions, active regions with no eruption, and an active region with an ongoing eruption. Using Stokes I images from SOLIS/VSM on 2012 March 13, variations in line width and peakedness of Fe I 6301.5 Å are shown to have a strong spatial and temporal relationship with an M7.9 X-ray flare originating from NOAA 11429. This relationship is observed as a flattening in the line profile as the X-ray flare approaches peak intensity and was not present in area scans of a non-eruptive active region on 2011 April 14. These results are used to estimate dynamic plasma properties on sub-pixel scales and provide both spatial and temporal information of sub-pixel activity at the photosphere. The analysis can be extended to include the full Stokes parameters and study signatures of magnetic fields and coupled plasma properties.

  4. Topography of Photosynthetic Activity of Leaves Obtained from Video Images of Chlorophyll Fluorescence 1

    PubMed Central

    Daley, Paul F.; Raschke, Klaus; Ball, J. Timothy; Berry, Joseph A.

    1989-01-01

    The distribution of photosynthetic activity over the area of a leaf and its change with time was determined (at low partial pressure of O2) by recording images of chlorophyll fluorescence during saturating light flashes. Simultaneously, the gas exchange was being measured. Reductions of local fluorescence intensity quantitatively displayed the extent of nonphotochemical quenching; quench coefficients, qN, were computed pixel by pixel. Because rates of photosynthetic electron transport are positively correlated with (1 − qN), computed images of (1 − qN) represented topographies of photosynthetic activity. Following application of abscisic acid to the heterobaric leaves of Xanthium strumarium L., clearly delineated regions varying in nonphotochemical quenching appeared that coincided with areoles formed by minor veins and indicated stomatal closure in groups. Images Figure 2 Figure 4 Figure 6 PMID:16666912

  5. ATLAS IBL Pixel Upgrade

    NASA Astrophysics Data System (ADS)

    La Rosa, A.; Atlas Ibl Collaboration

    2011-06-01

    The upgrade for ATLAS detector will undergo different phases towards super-LHC. The first upgrade for the Pixel detector will consist of the construction of a new pixel layer which will be installed during the first shutdown of the LHC machine (LHC phase-I upgrade). The new detector, called Insertable B-Layer (IBL), will be inserted between the existing pixel detector and a new (smaller radius) beam-pipe at a radius of 3.3 cm. The IBL will require the development of several new technologies to cope with increase of radiation or pixel occupancy and also to improve the physics performance which will be achieved by reducing the pixel size and of the material budget. Three different promising sensor technologies (planar-Si, 3D-Si and diamond) are currently under investigation for the pixel detector. An overview of the project with particular emphasis on the pixel module is presented in this paper.

  6. Design of pixel electronics based on asynchronous self-reset approach with floating-point output representation for high dynamic range imagers

    NASA Astrophysics Data System (ADS)

    Nascetti, A.; Valerio, P.

    2011-01-01

    A readout circuit suitable for multi-channel preamplifiers for pixellated detectors, hybrid detectors or thin film on asic imagers, for applications requiring large dynamic range such as computed tomography is discussed. The circuit implements an asynchronous self-reset with residue conversion scheme combined with a floating point representation of the input current. This solution allows to reach a very high dynamic range with good linearity while ensuring a compact output format. In particular, in the present implementation the input current range extends from 50 fA up to 820 nA corresponding to a 144 dB dynamic range which is equivalent to a 24-bit code. However the proposed scheme only uses 16 output bits for the floating point representation with 12-bit constant relative resolution: 12 bits serve for the output value itself and 4 for storing the position of the transition point between integer and fractional part. In addition, an analytical study of the achievable imaging performances shows that no significant degradation of the SNR is expected for the 12-bit constant relative resolution implementation with respect to the full 24-bit resolution scheme. Finally, the main building blocks of the circuit are analyzed in detail and their characteristics are put in relationship with the overall system performances.

  7. High-flux ptychographic imaging using the new 55 µm-pixel detector ‘Lambda’ based on the Medipix3 readout chip

    PubMed Central

    Wilke, R. N.; Wallentin, J.; Osterhoff, M.; Pennicard, D.; Zozulya, A.; Sprung, M.; Salditt, T.

    2014-01-01

    Suitable detection systems that are capable of recording high photon count rates with single-photon detection are instrumental for coherent X-ray imaging. The new single-photon-counting pixel detector ‘Lambda’ has been tested in a ptychographic imaging experiment on solar-cell nanowires using Kirkpatrick–Baez-focused 13.8 keV X-rays. Taking advantage of the high count rate of the Lambda and dynamic range expansion by the semi-transparent central stop, a high-dynamic-range diffraction signal covering more than seven orders of magnitude has been recorded, which corresponds to a photon flux density of about 105 photons nm−2 s−1 or a flux of ∼1010 photons s−1 on the sample. By comparison with data taken without the semi-transparent central stop, an increase in resolution by a factor of 3–4 is determined: from about 125 nm to about 38 nm for the nanowire and from about 83 nm to about 21 nm for the illuminating wavefield.

  8. A new approach for the pixel map sensitivity (PMS) evaluation of an electronic portal imaging device (EPID).

    PubMed

    Boriano, Alberto; Lucio, Francesco; Calamia, Elisa; Russi, Elvio; Marchetto, Flavio

    2013-11-04

    When using an electronic portal imaging device (EPID) for dosimetric verifications, the calibration of the sensitive area is of paramount importance. Two calibration methods are generally adopted: one, empirical, based on an external reference dosimeter or on multiple narrow beam irradiations, and one based on the EPID response simulation. In this paper we present an alternative approach based on an intercalibration procedure, independent from external dosimeters and from simulations, and is quick and easy to perform. Each element of a detector matrix is characterized by a different gain; the aim of the calibration procedure is to relate the gain of each element to a reference one. The method that we used to compute the relative gains is based on recursive acquisitions with the EPID placed in different positions, assuming a constant fluence of the beam for subsequent deliveries. By applying an established procedure and analysis algorithm, the EPID calibration was repeated in several working conditions. Data show that both the photons energy and the presence of a medium between the source and the detector affect the calibration coefficients less than 1%. The calibration coefficients were then applied to the acquired images, comparing the EPID dose images with films. Measurements were performed with open field, placing the film at the level of the EPID. The standard deviation of the distribution of the point-to-point difference is 0.6%. An approach of this type for the EPID calibration has many advantages with respect to the standard methods - it does not need an external dosimeter, it is not related to the irradiation techniques, and it is easy to implement in the clinical practice. Moreover, it can be applied in case of transit or nontransit dosimetry, solving the problem of the EPID calibration independently from the dose reconstruction method.

  9. Fast Pixel Buffer For Processing With Lookup Tables

    NASA Technical Reports Server (NTRS)

    Fisher, Timothy E.

    1992-01-01

    Proposed scheme for buffering data on intensities of picture elements (pixels) of image increases rate or processing beyond that attainable when data read, one pixel at time, from main image memory. Scheme applied in design of specialized image-processing circuitry. Intended to optimize performance of processor in which electronic equivalent of address-lookup table used to address those pixels in main image memory required for processing.

  10. Bad pixel mapping

    NASA Astrophysics Data System (ADS)

    Smith, Roger M.; Hale, David; Wizinowich, Peter

    2014-07-01

    Bad pixels are generally treated as a loss of useable area and then excluded from averaged performance metrics. The definition and detection of "bad pixels" or "cosmetic defects" are seldom discussed, perhaps because they are considered self-evident or of minor consequence for any scientific grade detector, however the ramifications can be more serious than generally appreciated. While the definition of pixel performance is generally understood, the classification of pixels as useable is highly application-specific, as are the consequences of ignoring or interpolating over such pixels. CMOS sensors (including NIR detectors) exhibit less compact distributions of pixel properties than CCDs. The extended tails in these distributions result in a steeper increase in bad pixel counts as performance thresholds are tightened which comes as a surprise to many users. To illustrate how some applications are much more sensitive to bad pixels than others, we present a bad pixel mapping exercise for the Teledyne H2RG used as the NIR tip-tilt sensor in the Keck-1 Adaptive Optics system. We use this example to illustrate the wide range of metrics by which a pixel might be judged inadequate. These include pixel bump bond connectivity, vignetting, addressing faults in the mux, severe sensitivity deficiency of some pixels, non linearity, poor signal linearity, low full well, poor mean-variance linearity, excessive noise and high dark current. Some pixels appear bad by multiple metrics. We also discuss the importance of distinguishing true performance outliers from measurement errors. We note how the complexity of these issues has ramifications for sensor procurement and acceptance testing strategies.

  11. A low-noise 15-μm pixel-pitch 640×512 hybrid InGaAs image sensor for night vision

    NASA Astrophysics Data System (ADS)

    Guellec, Fabrice; Dubois, Sébastien; de Borniol, Eric; Castelein, Pierre; Martin, Sébastien; Guiguet, Romain; Tchagaspanian, Micha"l.; Rouvié, Anne; Bois, Philippe

    2012-03-01

    Hybrid InGaAs focal plane arrays are very interesting for night vision because they can benefit from the nightglow emission in the Short Wave Infrared band. Through a collaboration between III-V Lab and CEA-Léti, a 640x512 InGaAs image sensor with 15μm pixel pitch has been developed. The good crystalline quality of the InGaAs detectors opens the door to low dark current (around 20nA/cm2 at room temperature and -0.1V bias) as required for low light level imaging. In addition, the InP substrate can be removed to extend the detection range towards the visible spectrum. A custom readout IC (ROIC) has been designed in a standard CMOS 0.18μm technology. The pixel circuit is based on a capacitive transimpedance amplifier (CTIA) with two selectable charge-to-voltage conversion gains. Relying on a thorough noise analysis, this input stage has been optimized to deliver low-noise performance in high-gain mode with a reasonable concession on dynamic range. The exposure time can be maximized up to the frame period thanks to a rolling shutter approach. The frame rate can be up to 120fps or 60fps if the Correlated Double Sampling (CDS) capability of the circuit is enabled. The first results show that the CDS is effective at removing the very low frequency noise present on the reference voltage in our test setup. In this way, the measured total dark noise is around 90 electrons in high-gain mode for 8.3ms exposure time. It is mainly dominated by the dark shot noise for a detector temperature settling around 30°C when not cooled. The readout noise measured with shorter exposure time is around 30 electrons for a dynamic range of 71dB in high-gain mode and 108 electrons for 79dB in low-gain mode.

  12. Photon counting readout pixel array in 0.18-μm CMOS technology for on-line gamma-ray imaging of 103palladium seeds for permanent breast seed implant (PBSI) brachytherapy

    NASA Astrophysics Data System (ADS)

    Goldan, A. H.; Karim, K. S.; Reznik, A.; Caldwell, C. B.; Rowlands, J. A.

    2008-03-01

    Permanent breast seed implant (PBSI) brachytherapy technique was recently introduced as an alternative to high dose rate (HDR) brachytherapy and involves the permanent implantation of radioactive 103Palladium seeds into the surgical cavity of the breast for cancer treatment. To enable accurate seed implantation, this research introduces a gamma camera based on a hybrid amorphous selenium detector and CMOS readout pixel architecture for real-time imaging of 103Palladium seeds during the PBSI procedure. A prototype chip was designed and fabricated in 0.18-μm n-well CMOS process. We present the experimental results obtained from this integrated photon counting readout pixel.

  13. Active learning for convenient annotation and classification of secondary ion mass spectrometry images.

    PubMed

    Hanselmann, Michael; Röder, Jens; Köthe, Ullrich; Renard, Bernhard Y; Heeren, Ron M A; Hamprecht, Fred A

    2013-01-02

    Digital staining for the automated annotation of mass spectrometry imaging (MSI) data has previously been achieved using state-of-the-art classifiers such as random forests or support vector machines (SVMs). However, the training of such classifiers requires an expert to label exemplary data in advance. This process is time-consuming and hence costly, especially if the tissue is heterogeneous. In theory, it may be sufficient to only label a few highly representative pixels of an MS image, but it is not known a priori which pixels to select. This motivates active learning strategies in which the algorithm itself queries the expert by automatically suggesting promising candidate pixels of an MS image for labeling. Given a suitable querying strategy, the number of required training labels can be significantly reduced while maintaining classification accuracy. In this work, we propose active learning for convenient annotation of MSI data. We generalize a recently proposed active learning method to the multiclass case and combine it with the random forest classifier. Its superior performance over random sampling is demonstrated on secondary ion mass spectrometry data, making it an interesting approach for the classification of MS images.

  14. Images of an Activated Asteroid

    NASA Astrophysics Data System (ADS)

    Kohler, Susanna

    2016-08-01

    In late April of this year, asteroid P/2016 G1 (PANSTARRS) was discovered streaking through space, a tail of dust extending behind it. What caused this asteroids dust activity?Asteroid or Comet?Images of asteroid P/2016 G1 at three different times: late April, late May, and mid June. The arrow in the center panel points out an asymmetric feature that can be explained if the asteroid initially ejected material in a single direction, perhaps due to an impact. [Moreno et al. 2016]Asteroid P/2016 G1 is an interesting case: though it has the orbital elements of a main-belt asteroid it orbits at just under three times the EarthSun distance, with an eccentricity of e ~ 0.21 its appearance is closer to that of a comet, with a dust tail extending 20 behind it.To better understand the nature and cause of this unusual asteroids activity, a team led by Fernando Moreno (Institute of Astrophysics of Andalusia, in Spain) performed deep observations of P/2016 G1 shortly after its discovery. The team used the 10.4-meter Great Canary Telescope to image the asteroid over the span of roughly a month and a half.A Closer Look at P/2016 G1P/2016 G1 lies in the inner region of the main asteroid belt, so it is unlikely to have any ices that suddenly sublimated, causing the outburst. Instead, Moreno and collaborators suggest that the asteroids tail may have been caused by an impact that disrupted the parent body.To test this idea, the team used computer simulations to model their observations of P/2016 G1s dust tail. Based on their models, they demonstrate that the asteroid was likely activated on February 10 2016 roughly 350 days before it reached perihelion in its orbit and its activity was a short-duration event, lasting only ~24 days. The teams models indicate that over these 24 days, the asteroid lost around 20 million kilograms of dust, and at its maximum activity level, it was ejecting around 8 kg/s!Comparison of the observation from late May (panel a) and two models: one in which

  15. Curiosity's Mars Hand Lens Imager (MAHLI): Inital Observations and Activities

    NASA Technical Reports Server (NTRS)

    Edgett, K. S.; Yingst, R. A.; Minitti, M. E.; Robinson, M. L.; Kennedy, M. R.; Lipkaman, L. J.; Jensen, E. H.; Anderson, R. C.; Bean, K. M.; Beegle, L. W.; Carsten, J. L.; Collins, C. L.; Cooper, B.; Deen, R. G.; Gupta, S.

    2013-01-01

    MAHLI (Mars Hand Lens Imager) is a 2-megapixel focusable macro lens color camera on the turret on Curiosity's robotic arm. The investigation centers on stratigraphy, grain-scale texture, structure, mineralogy, and morphology of geologic materials at Curiosity's Gale robotic field site. MAHLI acquires focused images at working distances of 2.1 cm to infinity; for reference, at 2.1 cm the scale is 14 microns/pixel; at 6.9 cm it is 31 microns/pixel, like the Spirit and Opportunity Microscopic Imager (MI) cameras.

  16. Pixel selection for near-infrared chemical imaging (NIR-CI) discrimination between fish and terrestrial animal species in animal protein by-product meals.

    PubMed

    Riccioli, Cecilia; Pérez-Marín, Dolores; Guerrero-Ginel, José Emilio; Saeys, Wouter; Garrido-Varo, Ana

    2011-07-01

    This paper proposes a method based on near-infrared hyperspectral imaging for discriminating between terrestrial and fish species in animal protein by-products used in livestock feed. Four algorithms (Mahalanobis distance, Kennard-Stone, spatial interpolation, and binning) were compared in order to select an appropriate subset of pixels for further partial least squares discriminant analysis (PLS-DA). The method was applied to a set of 50 terrestrial and 40 fish meals analyzed in the 1000-1700 nm range. Models were then tested using an external validation set comprising 45 samples (25 fish and 20 terrestrial). The PLS-DA models obtained using the four subset-selection algorithms yielded a classification accuracy of 99.80%, 99.79%, 99.85%, and 99.61%, respectively. The results represent a first step for the analysis of mixtures of species and suggest that NIR-CI, providing valuable information on the origin of animal components in processed animal proteins, is a promising method that could be used as part of the EU feed control program aimed at eradicating and preventing bovine spongiform encephalopathy (BSE) and related diseases.

  17. Low-noise reset technique of an asynchronous charge-pulse-detecting pixel for single-photon X-ray imaging

    NASA Astrophysics Data System (ADS)

    Kim, Hyun-Sik; Han, Kwan-Young

    2016-02-01

    This paper presents a low-noise reset technique of an asynchronous charge-pulse-detecting pixel for single-photon X-ray imaging. The proposed slow-slope ramp (S2R) reset scheme provides a reset-noise-discharging loop circuit and effectively eliminates the residual noise charge stored on the sampling capacitor by extending the falling transition time of the reset signal. In addition, the presented S2R reset signal generation circuit accurately and effectively controls the optimum switching voltage and the falling transition time of the reset signal. The prototype detector chip was implemented by using a 130-nm complementary metal-oxide semiconductor (CMOS) process. With the quantitative analysis and the measurement results, we were able to verify that the reset noise was reduced exponentially, corresponding to the falling transition time of the reset signal. Based on the chip measurement results, the reset-noise level could be decreased by more than seven-fold by virtue of the proposed reset technique.

  18. Fueling and imaging brain activation

    PubMed Central

    Dienel, Gerald A

    2012-01-01

    Metabolic signals are used for imaging and spectroscopic studies of brain function and disease and to elucidate the cellular basis of neuroenergetics. The major fuel for activated neurons and the models for neuron–astrocyte interactions have been controversial because discordant results are obtained in different experimental systems, some of which do not correspond to adult brain. In rats, the infrastructure to support the high energetic demands of adult brain is acquired during postnatal development and matures after weaning. The brain's capacity to supply and metabolize glucose and oxygen exceeds demand over a wide range of rates, and the hyperaemic response to functional activation is rapid. Oxidative metabolism provides most ATP, but glycolysis is frequently preferentially up-regulated during activation. Underestimation of glucose utilization rates with labelled glucose arises from increased lactate production, lactate diffusion via transporters and astrocytic gap junctions, and lactate release to blood and perivascular drainage. Increased pentose shunt pathway flux also causes label loss from C1 of glucose. Glucose analogues are used to assay cellular activities, but interpretation of results is uncertain due to insufficient characterization of transport and phosphorylation kinetics. Brain activation in subjects with low blood-lactate levels causes a brain-to-blood lactate gradient, with rapid lactate release. In contrast, lactate flooding of brain during physical activity or infusion provides an opportunistic, supplemental fuel. Available evidence indicates that lactate shuttling coupled to its local oxidation during activation is a small fraction of glucose oxidation. Developmental, experimental, and physiological context is critical for interpretation of metabolic studies in terms of theoretical models. PMID:22612861

  19. It's not the pixel count, you fool

    NASA Astrophysics Data System (ADS)

    Kriss, Michael A.

    2012-01-01

    The first thing a "marketing guy" asks the digital camera engineer is "how many pixels does it have, for we need as many mega pixels as possible since the other guys are killing us with their "umpteen" mega pixel pocket sized digital cameras. And so it goes until the pixels get smaller and smaller in order to inflate the pixel count in the never-ending pixel-wars. These small pixels just are not very good. The truth of the matter is that the most important feature of digital cameras in the last five years is the automatic motion control to stabilize the image on the sensor along with some very sophisticated image processing. All the rest has been hype and some "cool" design. What is the future for digital imaging and what will drive growth of camera sales (not counting the cell phone cameras which totally dominate the market in terms of camera sales) and more importantly after sales profits? Well sit in on the Dark Side of Color and find out what is being done to increase the after sales profits and don't be surprised if has been done long ago in some basement lab of a photographic company and of course, before its time.

  20. Active Metamaterials for Terahertz Communication and Imaging

    NASA Astrophysics Data System (ADS)

    Rout, Saroj

    In recent years there has been significant interest in terahertz (THz) systems mostly due to their unique applications in communication and imaging. One of the primary reason for this resurgence is the use of metamaterials to design THz devices due to lack of natural materials that can respond to this electromagnetic spectrum, the so-called ''THz gap''. Even after years of intense research, THz systems are complex and expensive, unsuitable for mainstream applications. This work focuses on bridging this gap by building all solid-state THz devices for imaging and communication applications in a commercial integrated circuit (IC) technology. One such canonical device is a THz wave modulator that can be used in THz wireless communication devices and as spatial light modulator (SLM) for THz imaging systems. The key contribution of this thesis is a metamaterial based THz wave modulator fabricated in a commercial gallium arsenide (GaAs) process resonant at 0.46 THz using a novel approach of embedding pseudomorphic high electron mobility transistors (pHEMTs) in metamaterial and demonstrate modulation values over 30%, and THz modulation at frequencies up to 10 MHz. Using the THz wave modulator, we fabricated and experimentally demonstrated an all solid-state metamaterial based THz spatial light modulator (SLM) as a 2x2 pixel array operating around 0.46 THz, by raster scanning an occluded metal object in polystyrene using a single-pixel imaging setup. This was an important step towards building an low-voltage (1V), low power, on-chip integrable THz imaging device. Using the characterization result from the THz SLM, we computationally demonstrated a multi-level amplitude shift keying (ASK) terahertz wireless communication system using spatial light modulation instead of traditional voltage mode modulation, achieving higher spectral efficiency for high speed communication. We show two orders of magnitude improvement in symbol error rate (SER) for a degradation of 20 dB in

  1. Range-gated intensified spectrographic imager: an instrument for active hyperspectral imaging

    NASA Astrophysics Data System (ADS)

    Simard, Jean-Robert; Mathieu, Pierre; Fournier, Georges R.; Larochelle, Vincent; Babey, Stephen K.

    2000-09-01

    Hyperspectral imaging has demonstrated impressive capabilities in airborne surveys, particularly for mineral and biomass characterizations. Based on this success, it is believed that other applications like search and rescue operations, and detection/identification of various ground military targets could greatly benefit from this technology. The strength of hyperspectral imaging comes from the access to another dimension of information: the spectral content of the detected return signal for each spatial pixel. In the case of conventional hyperspectral imaging, the return signal depicts the spectral reflectance of the day irradiance from the scene within the field of view of each pixel. However, by inserting a range-gated intensifier into a hyperspectral camera and by combining the camera with selected pulsed lasers, it becomes possible to relate the returned spectral information to specific light/matter interactions like induced fluorescence. This new technique may be referred to as 'active hyperspectral imaging.' Among its advantages, this approach is independent of the ambient lighting conditions and can be customized in excitation wavelengths. Moreover, by using a range-gated intensified camera, it is possible to survey limited area with a significant increase in signal-to-noise ratio. A camera of this type has been built by our group in collaboration with private industry and is described in this paper. The internal design of the camera is discussed, new issues concerning the calibration of the camera are depicted and a model based on signal-to-noise ratio analysis is presented. From the fluorescent characteristics of surrogate land mines measured in the laboratory, this model is used to predict the capabilities of detecting surface-laid mines from an aerial platform based scenario.

  2. A column level, low power, 1 M sample/s double ramp A/D converter for monolithic active pixel sensors in high energy physics

    NASA Astrophysics Data System (ADS)

    Pillet, N.; Heini, S.; Hu, Y.

    2010-08-01

    Monolithic active pixel sensors (MAPS) using standard low cost CMOS technologies available from industrial manufacturers have demonstrated excellent tracking performances for minimum ionizing particles. The need for highly granular, fast, thin sensors with a full digital output drives an R&D effort, aiming to design and optimize a low power high speed A/D converter integrated at the column level. Following this main issue, a double digital ramp A/D converter has been proposed for CMOS monolithic active pixel sensors in this paper. This A/D converter responds to the constraints of size, power dissipation and precision for CMOS sensors for particle detection. It also represents a first step in order to reach the high speed of conversion needed for this kind of application. The A/D converter has a resolution of 4 bits for conversion speed of 1 M sample/s with only 264 μW of static consumption in a very particular pitch of 25 μm×900 μm.

  3. A Pixel Readout Chip in 40 nm CMOS Process for High Count Rate Imaging Systems with Minimization of Charge Sharing Effects

    SciTech Connect

    Maj, Piotr; Grybos, P.; Szczgiel, R.; Kmon, P.; Drozd, A.; Deptuch, G.

    2013-11-07

    We present a prototype chip in 40 nm CMOS technology for readout of hybrid pixel detector. The prototype chip has a matrix of 18x24 pixels with a pixel pitch of 100 μm. It can operate both in single photon counting (SPC) mode and in C8P1 mode. In SPC the measured ENC is 84 erms (for the peaking time of 48 ns), while the effective offset spread is below 2 mV rms. In the C8P1 mode the chip reconstructs full charge deposited in the detector, even in the case of charge sharing, and it identifies a pixel with the largest charge deposition. The chip architecture and preliminary measurements are reported.

  4. Hinode Captures Images of Solar Active Region

    NASA Video Gallery

    In these images, Hinode's Solar Optical Telescope (SOT) zoomed in on AR 11263 on August 4, 2011, five days before the active region produced the largest flare of this cycle, an X6.9. We show images...

  5. Per-Pixel Lighting Data Analysis

    SciTech Connect

    Inanici, Mehlika

    2005-08-01

    This report presents a framework for per-pixel analysis of the qualitative and quantitative aspects of luminous environments. Recognizing the need for better lighting analysis capabilities and appreciating the new measurement abilities developed within the LBNL Lighting Measurement and Simulation Toolbox, ''Per-pixel Lighting Data Analysis'' project demonstrates several techniques for analyzing luminance distribution patterns, luminance ratios, adaptation luminance and glare assessment. The techniques are the syntheses of the current practices in lighting design and the unique practices that can be done with per-pixel data availability. Demonstrated analysis techniques are applicable to both computer-generated and digitally captured images (physically-based renderings and High Dynamic Range photographs).

  6. Submillimeter Confocal Imaging Active Module

    NASA Technical Reports Server (NTRS)

    Hong, John; Mehdi, Imran; Siegel, Peter; Chattopadhyay, Goutam; Cwik, Thomas; Rowell, Mark; Hacker, John

    2009-01-01

    The term submillimeter confocal imaging active module (SCIAM) denotes a proposed airborne coherent imaging radar system that would be suitable for use in reconnaissance, surveillance, and navigation. The development of the SCIAM would include utilization and extension of recent achievements in monolithic microwave integrated circuits capable of operating at frequencies up to and beyond a nominal radio frequency of 340 GHz. Because the SCIAM would be primarily down-looking (in contradistinction to primarily side-looking), it could be useful for imaging shorter objects located between taller ones (for example, objects on streets between buildings). The SCIAM would utilize a confocal geometry to obtain high cross-track resolution, and would be amenable to synthetic-aperture processing of its output to obtain high along-track resolution. The SCIAM (see figure) would include multiple (two in the initial version) antenna apertures, separated from each other by a cross-track baseline of suitable length (e.g., 1.6 m). These apertures would both transmit the illuminating radar pulses and receive the returns. A common reference oscillator would generate a signal at a controllable frequency of (340 GHz + (Delta)f)/N, where (Delta)f is an instantaneous swept frequency difference and N is an integer. The output of this oscillator would be fed to a frequency- multiplier-and-power-amplifier module to obtain a signal, at 340 GHz + (Delta)f, that would serve as both the carrier signal for generating the transmitted pulses and a local-oscillator (LO) signal for a receiver associated with each antenna aperture. Because duplexers in the form of circulators or transmit/receive (T/R) switches would be lossy and extremely difficult to implement, the antenna apertures would be designed according to a spatial-diplexing scheme, in which signals would be coupled in and out via separate, adjacent transmitting and receiving feed horns. This scheme would cause the transmitted and received beams

  7. High density pixel array

    NASA Technical Reports Server (NTRS)

    Wiener-Avnear, Eliezer (Inventor); McFall, James Earl (Inventor)

    2004-01-01

    A pixel array device is fabricated by a laser micro-milling method under strict process control conditions. The device has an array of pixels bonded together with an adhesive filling the grooves between adjacent pixels. The array is fabricated by moving a substrate relative to a laser beam of predetermined intensity at a controlled, constant velocity along a predetermined path defining a set of grooves between adjacent pixels so that a predetermined laser flux per unit area is applied to the material, and repeating the movement for a plurality of passes of the laser beam until the grooves are ablated to a desired depth. The substrate is of an ultrasonic transducer material in one example for fabrication of a 2D ultrasonic phase array transducer. A substrate of phosphor material is used to fabricate an X-ray focal plane array detector.

  8. Development of a pixelated CdTe detector module for a hard-x and gamma-ray imaging spectrometer application

    NASA Astrophysics Data System (ADS)

    Galvèz, J.-L.; Hernanz, M.; Álvarez, L.; Artigues, B.; Álvarez, J.-M.; Ullán, M.; Lozano, M.; Pellegrini, G.; Cabruja, E.; Martínez, R.; Chmeissani, M.; Puigdengoles, C.

    2016-07-01

    Stellar explosions are relevant and interesting astrophysical phenomena. Since long ago we have been working on the characterization of novae and supernovae in X and gamma-rays, with the use of space missions. We have also been involved in feasibility studies of future instruments in the energy range from several keV up to a few MeV, in collaboration with other research institutes. High sensitivities are essential to perform detailed studies of cosmic explosions and cosmic accelerators, e.g., Supernovae and Classical Novae. In order to fulfil the combined requirement of high detection efficiency with good spatial and energy resolution, an initial module prototype based on CdTe pixel detectors is being developed. The detector dimensions are 12.5mm x 12.5mm x 2mm with a pixel pitch of 1mm x 1mm. Two kinds of CdTe pixel detectors with different contacts have been tested: ohmic and Schottky. Each pixel is bump bonded to a fanout board made of Sapphire substrate and routed to the corresponding input channel of the readout VATAGP7.1 ASIC, to measure pixel position and pulse height for each incident gamma-ray photon. The study is complemented by the simulation of the CdTe module performance using the GEANT 4 and MEGALIB tools, which will help us to optimise the detector design. We will report on the spectroscopy characterisation of the CdTe detector module as well as the study of charge sharing.

  9. Active contour segmentation using level set function with enhanced image from prior intensity.

    PubMed

    Kim, Sunhee; Kim, Youngjun; Lee, Deukhee; Park, Sehyung

    2015-01-01

    This paper presents a new active contour segmentation model using a level set function that can correctly capture both the strong and the weak boundaries of a target enclosed by bright and dark regions at the same time. We introduce an enhanced image obtained from prior information about the intensity of the target. The enhanced image emphasizes the regions where pixels have intensities close to the prior intensity. This enables a desirable segmentation of an image having a partially low contrast with the target surrounded by regions that are brighter or darker than the target. We define an edge indicator function on an original image, and local and regularization forces on an enhanced image. An edge indicator function and two forces are incorporated in order to identify the strong and weak boundaries, respectively. We established an evolution equation of contours in the level set formulation and experimented with several medical images to show the performance of the proposed method.

  10. Characterization of bias induced metastability of amorphous silicon thin film transistor based passive pixel sensor switch and its impact on biomedical x-ray imaging application

    NASA Astrophysics Data System (ADS)

    Sultana, Afrin; Safavian, N.; Izadi, M. H.; Karim, K. S.; Rowlands, J. A.

    2009-02-01

    Active Matrix Flat Panel Imagers (AMFPIs) based on amorphous silicon (a-Si:H) thin film transistor (TFT) array is the most promising technology for large area biomedical x-ray imaging. a-Si:H TFT exhibits a metastable shift in its characteristics when subject to prolonged gate bias that results in a change in its threshold voltage (VΤ) and a corresponding change in ON resistance (RON). If not properly accounted for, the VΤ shift can be a major constraint in imaging applications as it contributes to the fixed pattern noise in the imager. In this work, we investigated the timedependent shift in VΤ (ΔVΤ) of a-Si:H TFTs stressed with the same bipolar pulsed bias used for static (chest radiography, mammography, and static protein crystallography) and real time imaging (low dose fluoroscopy at 15, 30 and 60 frames/second, and dynamic protein crystallography). We used the well known power law model of time dependent ΔVT to estimate the change in RON over time. Our calculation showed that RON can be decreased ~ 0.03 % per frame and ~ 5 % over 10,000 hours at 30 frames/second. We verified the theoretical results with measurement data. The implication of TFT metastability on the performance (NPS, and DQE) of biomedical imagers is discussed.

  11. How many pixels does it take to make a good 4"×6" print? Pixel count wars revisited

    NASA Astrophysics Data System (ADS)

    Kriss, Michael A.

    2011-01-01

    In the early 1980's the future of conventional silver-halide photographic systems was of great concern due to the potential introduction of electronic imaging systems then typified by the Sony Mavica analog electronic camera. The focus was on the quality of film-based systems as expressed in the number of equivalent number pixels and bits-per-pixel, and how many pixels would be required to create an equivalent quality image from a digital camera. It was found that 35-mm frames, for ISO 100 color negative film, contained equivalent pixels of 12 microns for a total of 18 million pixels per frame (6 million pixels per layer) with about 6 bits of information per pixel; the introduction of new emulsion technology, tabular AgX grains, increased the value to 8 bit per pixel. Higher ISO speed films had larger equivalent pixels, fewer pixels per frame, but retained the 8 bits per pixel. Further work found that a high quality 3.5" x 5.25" print could be obtained from a three layer system containing 1300 x 1950 pixels per layer or about 7.6 million pixels in all. In short, it became clear that when a digital camera contained about 6 million pixels (in a single layer using a color filter array and appropriate image processing) that digital systems would challenge and replace conventional film-based system for the consumer market. By 2005 this became the reality. Since 2005 there has been a "pixel war" raging amongst digital camera makers. The question arises about just how many pixels are required and are all pixels equal? This paper will provide a practical look at how many pixels are needed for a good print based on the form factor of the sensor (sensor size) and the effective optical modulation transfer function (optical spread function) of the camera lens. Is it better to have 16 million, 5.7-micron pixels or 6 million 7.8-micron pixels? How does intrinsic (no electronic boost) ISO speed and exposure latitude vary with pixel size? A systematic review of these issues will

  12. Mapping Capacitive Coupling Among Pixels in a Sensor Array

    NASA Technical Reports Server (NTRS)

    Seshadri, Suresh; Cole, David M.; Smith, Roger M.

    2010-01-01

    An improved method of mapping the capacitive contribution to cross-talk among pixels in an imaging array of sensors (typically, an imaging photodetector array) has been devised for use in calibrating and/or characterizing such an array. The method involves a sequence of resets of subarrays of pixels to specified voltages and measurement of the voltage responses of neighboring non-reset pixels.

  13. Comparative study of various pixel photodiodes for digital radiography: Junction structure, corner shape and noble window opening

    NASA Astrophysics Data System (ADS)

    Kang, Dong-Uk; Cho, Minsik; Lee, Dae Hee; Yoo, Hyunjun; Kim, Myung Soo; Bae, Jun Hyung; Kim, Hyoungtaek; Kim, Jongyul; Kim, Hyunduk; Cho, Gyuseong

    2012-05-01

    Recently, large-size 3-transistors (3-Tr) active pixel complementary metal-oxide silicon (CMOS) image sensors have been being used for medium-size digital X-ray radiography, such as dental computed tomography (CT), mammography and nondestructive testing (NDT) for consumer products. We designed and fabricated 50 µm × 50 µm 3-Tr test pixels having a pixel photodiode with various structures and shapes by using the TSMC 0.25-m standard CMOS process to compare their optical characteristics. The pixel photodiode output was continuously sampled while a test pixel was continuously illuminated by using 550-nm light at a constant intensity. The measurement was repeated 300 times for each test pixel to obtain reliable results on the mean and the variance of the pixel output at each sampling time. The sampling rate was 50 kHz, and the reset period was 200 msec. To estimate the conversion gain, we used the mean-variance method. From the measured results, the n-well/p-substrate photodiode, among 3 photodiode structures available in a standard CMOS process, showed the best performance at a low illumination equivalent to the typical X-ray signal range. The quantum efficiencies of the n+/p-well, n-well/p-substrate, and n+/p-substrate photodiodes were 18.5%, 62.1%, and 51.5%, respectively. From a comparison of pixels with rounded and rectangular corners, we found that a rounded corner structure could reduce the dark current in large-size pixels. A pixel with four rounded corners showed a reduced dark current of about 200fA compared to a pixel with four rectangular corners in our pixel sample size. Photodiodes with round p-implant openings showed about 5% higher dark current, but about 34% higher sensitivities, than the conventional photodiodes.

  14. RGB-NIR active gated imaging

    NASA Astrophysics Data System (ADS)

    Spooren, Nick; Geelen, Bert; Tack, Klaas; Lambrechts, Andy; Jayapala, Murali; Ginat, Ran; David, Yaara; Levi, Eyal; Grauer, Yoav

    2016-10-01

    This paper presents multispectral active gated imaging in relation to the transportation and security fields. Active gated imaging is based on a fast gated camera and pulsed illuminator, synchronized in the time domain to provide range based images. We have developed a multispectral pattern deposited on a gated CMOS Image Sensor (CIS) with a pulsed Near Infrared VCSEL module. This paper will cover the component-level description of the multispectral gated CIS including the camera and illuminator units. Furthermore, the design considerations and characterization results of the spectral filters are presented together with a newly developed image processing method.

  15. Design, optimization and evaluation of a "smart" pixel sensor array for low-dose digital radiography

    NASA Astrophysics Data System (ADS)

    Wang, Kai; Liu, Xinghui; Ou, Hai; Chen, Jun

    2016-04-01

    Amorphous silicon (a-Si:H) thin-film transistors (TFTs) have been widely used to build flat-panel X-ray detectors for digital radiography (DR). As the demand for low-dose X-ray imaging grows, a detector with high signal-to-noise-ratio (SNR) pixel architecture emerges. "Smart" pixel is intended to use a dual-gate photosensitive TFT for sensing, storage, and switch. It differs from a conventional passive pixel sensor (PPS) and active pixel sensor (APS) in that all these three functions are combined into one device instead of three separate units in a pixel. Thus, it is expected to have high fill factor and high spatial resolution. In addition, it utilizes the amplification effect of the dual-gate photosensitive TFT to form a one-transistor APS that leads to a potentially high SNR. This paper addresses the design, optimization and evaluation of the smart pixel sensor and array for low-dose DR. We will design and optimize the smart pixel from the scintillator to TFT levels and validate it through optical and electrical simulation and experiments of a 4x4 sensor array.

  16. Mapping Electrical Crosstalk in Pixelated Sensor Arrays

    NASA Technical Reports Server (NTRS)

    Seshadri, S.; Cole, D. M.; Hancock, B. R.; Smith, R. M.

    2008-01-01

    Electronic coupling effects such as Inter-Pixel Capacitance (IPC) affect the quantitative interpretation of image data from CMOS, hybrid visible and infrared imagers alike. Existing methods of characterizing IPC do not provide a map of the spatial variation of IPC over all pixels. We demonstrate a deterministic method that provides a direct quantitative map of the crosstalk across an imager. The approach requires only the ability to reset single pixels to an arbitrary voltage, different from the rest of the imager. No illumination source is required. Mapping IPC independently for each pixel is also made practical by the greater S/N ratio achievable for an electrical stimulus than for an optical stimulus, which is subject to both Poisson statistics and diffusion effects of photo-generated charge. The data we present illustrates a more complex picture of IPC in Teledyne HgCdTe and HyViSi focal plane arrays than is presently understood, including the presence of a newly discovered, long range IPC in the HyViSi FPA that extends tens of pixels in distance, likely stemming from extended field effects in the fully depleted substrate. The sensitivity of the measurement approach has been shown to be good enough to distinguish spatial structure in IPC of the order of 0.1%.

  17. ACS/WFC Pixel Stability - Bringing the Pixels Back to the Science

    NASA Astrophysics Data System (ADS)

    Borncamp, David; Grogin, Norman A.; Bourque, Matthew; Ogaz, Sara

    2016-06-01

    Electrical current that has been trapped within the lattice structure of a Charged Coupled Device (CCD) can be present through multiple exposures, which will have an adverse effect on its science performance. The traditional way to correct for this extra charge is to take an image with the camera shutter closed periodically throughout the lifetime of the instrument. These images, generally referred to as dark images, allow for the characterization of the extra charge that is trapped within the CCD at the time of observation. This extra current can then be subtracted out of science images to correct for the extra charge that was there at this time. Pixels that have a charge above a certain threshold of current are marked as “hot” and flagged in the data quality array. However, these pixels may not be "bad" in the traditional sense that they cannot be reliably dark-subtracted. If these pixels are shown to be stable over an anneal period, the charge can be properly subtracted and the extra noise from this dark current can be taken into account. We present the results of a pixel history study that analyzes every pixel of ACS/WFC individually and allows pixels that were marked as bad to be brought back into the science image.

  18. Infrared astronomy - Pixels to spare

    SciTech Connect

    Mccaughrean, M. )

    1991-07-01

    An infrared CCD camera containing an array with 311,040 pixels arranged in 486 rows of 640 each is tested. The array is a chip of platinum silicide (PtSi), sensitive to photons with wavelengths between 1 and 6 microns. Observations of the Hubble Space Telescope, Mars, Pluto and moon are reported. It is noted that the satellite's twin solar-cell arrays, at an apparent separation of about 1 1/4 arc second, are well resolved. Some two dozen video frames were stacked to make each presented image of Mars at 1.6 microns; at this wavelength Mars appears much as it does in visible light. A stack of 11 images at a wavelength of 1.6 microns is used for an image of Jupiter with its Great Red Spot and moons Io and Europa.

  19. Sub-pixel mapping of hyperspectral imagery using super-resolution

    NASA Astrophysics Data System (ADS)

    Sharma, Shreya; Sharma, Shakti; Buddhiraju, Krishna M.

    2016-04-01

    With the development of remote sensing technologies, it has become possible to obtain an overview of landscape elements which helps in studying the changes on earth's surface due to climate, geological, geomorphological and human activities. Remote sensing measures the electromagnetic radiations from the earth's surface and match the spectral similarity between the observed signature and the known standard signatures of the various targets. However, problem lies when image classification techniques assume pixels to be pure. In hyperspectral imagery, images have high spectral resolution but poor spatial resolution. Therefore, the spectra obtained is often contaminated due to the presence of mixed pixels and causes misclassification. To utilise this high spectral information, spatial resolution has to be enhanced. Many factors make the spatial resolution one of the most expensive and hardest to improve in imaging systems. To solve this problem, post-processing of hyperspectral images is done to retrieve more information from the already acquired images. The algorithm to enhance spatial resolution of the images by dividing them into sub-pixels is known as super-resolution and several researches have been done in this domain.In this paper, we propose a new method for super-resolution based on ant colony optimization and review the popular methods of sub-pixel mapping of hyperspectral images along with their comparative analysis.

  20. Making a trillion pixels dance

    NASA Astrophysics Data System (ADS)

    Singh, Vivek; Hu, Bin; Toh, Kenny; Bollepalli, Srinivas; Wagner, Stephan; Borodovsky, Yan

    2008-03-01

    In June 2007, Intel announced a new pixelated mask technology. This technology was created to address the problem caused by the growing gap between the lithography wavelength and the feature sizes patterned with it. As this gap has increased, the quality of the image has deteriorated. About a decade ago, Optical Proximity Correction (OPC) was introduced to bridge this gap, but as this gap continued to increase, one could not rely on the same basic set of techniques to maintain image quality. The computational lithography group at Intel sought to alleviate this problem by experimenting with additional degrees of freedom within the mask. This paper describes the resulting pixelated mask technology, and some of the computational methods used to create it. The first key element of this technology is a thick mask model. We realized very early in the development that, unlike traditional OPC methods, the pixelated mask would require a very accurate thick mask model. Whereas in the traditional methods, one can use the relatively coarse approximations such as the boundary layer method, use of such techniques resulted not just in incorrect sizing of parts of the pattern, but in whole features missing. We built on top of previously published domain decomposition methods, and incorporated limitations of the mask manufacturing process, to create an accurate thick mask model. Several additional computational techniques were invoked to substantially increase the speed of this method to a point that it was feasible for full chip tapeout. A second key element of the computational scheme was the comprehension of mask manufacturability, including the vital issue of the number of colors in the mask. While it is obvious that use of three or more colors will give the best image, one has to be practical about projecting mask manufacturing capabilities for such a complex mask. To circumvent this serious issue, we eventually settled on a two color mask - comprising plain glass and etched

  1. Selecting Pixels for Kepler Downlink

    NASA Technical Reports Server (NTRS)

    Bryson, Stephen T.; Jenkins, Jon M.; Klaus, Todd C.; Cote, Miles T.; Quintana, Elisa V.; Hall, Jennifer R.; Ibrahim, Khadeejah; Chandrasekaran, Hema; Caldwell, Douglas A.; Van Cleve, Jeffrey E.; Haas, Michael R.

    2010-01-01

    The Kepler mission monitors > 100,000 stellar targets using 42 2200 1024 pixel CCDs. Bandwidth constraints prevent the downlink of all 96 million pixels per 30-minute cadence, so the Kepler spacecraft downlinks a specified collection of pixels for each target. These pixels are selected by considering the object brightness, background and the signal-to-noise of each pixel, and are optimized to maximize the signal-to-noise ratio of the target. This paper describes pixel selection, creation of spacecraft apertures that efficiently capture selected pixels, and aperture assignment to a target. Diagnostic apertures, short-cadence targets and custom specified shapes are discussed.

  2. How Many Pixels Does It Take to Make a Good 4"×6" Print? Pixel Count Wars Revisited

    NASA Astrophysics Data System (ADS)

    Kriss, Michael A.

    Digital still cameras emerged following the introduction of the Sony Mavica analog prototype camera in 1981. These early cameras produced poor image quality and did not challenge film cameras for overall quality. By 1995 digital still cameras in expensive SLR formats had 6 mega-pixels and produced high quality images (with significant image processing). In 2005 significant improvement in image quality was apparent and lower prices for digital still cameras (DSCs) started a rapid decline in film usage and film camera sells. By 2010 film usage was mostly limited to professionals and the motion picture industry. The rise of DSCs was marked by a “pixel war” where the driving feature of the cameras was the pixel count where even moderate cost, ˜120, DSCs would have 14 mega-pixels. The improvement of CMOS technology pushed this trend of lower prices and higher pixel counts. Only the single lens reflex cameras had large sensors and large pixels. The drive for smaller pixels hurt the quality aspects of the final image (sharpness, noise, speed, and exposure latitude). Only today are camera manufactures starting to reverse their course and producing DSCs with larger sensors and pixels. This paper will explore why larger pixels and sensors are key to the future of DSCs.

  3. Local Histograms for Per-Pixel Classification

    DTIC Science & Technology

    2012-03-01

    Domain-Knowledge-Inspired Math - ematical Framework for the Description and Classification of H&E Stained Histopathology Images,” Proceedings of SPIE, 8138... computed over discrete images as the number of pixels in a particular bin. In order to obtain a “density” independent of the bin-width, one can divide the...Notes in Computer Science , 5112: 688–696 (2008). [12] van Ginneken, Bram and Bart M. ter Haar Romeny. “Applications of Locally Orderless Images

  4. 18F-FDG positron autoradiography with a particle counting silicon pixel detector.

    PubMed

    Russo, P; Lauria, A; Mettivier, G; Montesi, M C; Marotta, M; Aloj, L; Lastoria, S

    2008-11-07

    We report on tests of a room-temperature particle counting silicon pixel detector of the Medipix2 series as the detector unit of a positron autoradiography (AR) system, for samples labelled with (18)F-FDG radiopharmaceutical used in PET studies. The silicon detector (1.98 cm(2) sensitive area, 300 microm thick) has high intrinsic resolution (55 microm pitch) and works by counting all hits in a pixel above a certain energy threshold. The present work extends the detector characterization with (18)F-FDG of a previous paper. We analysed the system's linearity, dynamic range, sensitivity, background count rate, noise, and its imaging performance on biological samples. Tests have been performed in the laboratory with (18)F-FDG drops (37-37 000 Bq initial activity) and ex vivo in a rat injected with 88.8 MBq of (18)F-FDG. Particles interacting in the detector volume produced a hit in a cluster of pixels whose mean size was 4.3 pixels/event at 11 keV threshold and 2.2 pixels/event at 37 keV threshold. Results show a sensitivity for beta(+) of 0.377 cps Bq(-1), a dynamic range of at least five orders of magnitude and a lower detection limit of 0.0015 Bq mm(-2). Real-time (18)F-FDG positron AR images have been obtained in 500-1000 s exposure time of thin (10-20 microm) slices of a rat brain and compared with 20 h film autoradiography of adjacent slices. The analysis of the image contrast and signal-to-noise ratio in a rat brain slice indicated that Poisson noise-limited imaging can be approached in short (e.g. 100 s) exposures, with approximately 100 Bq slice activity, and that the silicon pixel detector produced a higher image quality than film-based AR.

  5. Characterisation of edgeless technologies for pixellated and strip silicon detectors with a micro-focused X-ray beam

    NASA Astrophysics Data System (ADS)

    Bates, R.; Blue, A.; Christophersen, M.; Eklund, L.; Ely, S.; Fadeyev, V.; Gimenez, E.; Kachkanov, V.; Kalliopuska, J.; Macchiolo, A.; Maneuski, D.; Phlips, B. F.; Sadrozinski, H. F.-W.; Stewart, G.; Tartoni, N.; Zain, R. M.

    2013-01-01

    Reduced edge or ``edgeless'' detector design offers seamless tileability of sensors for a wide range of applications from particle physics to synchrotron and free election laser (FEL) facilities and medical imaging. Combined with through-silicon-via (TSV) technology, this would allow reduced material trackers for particle physics and an increase in the active area for synchrotron and FEL pixel detector systems. In order to quantify the performance of different edgeless fabrication methods, 2 edgeless detectors were characterized at the Diamond Light Source using an 11 μm FWHM 15 keV micro-focused X-ray beam. The devices under test were: a 150 μm thick silicon active edge pixel sensor fabricated at VTT and bump-bonded to a Medipix2 ROIC; and a 300 μm thick silicon strip sensor fabricated at CIS with edge reduction performed by SCIPP and the NRL and wire bonded to an ALiBaVa readout system. Sub-pixel resolution of the 55 μm active edge pixels was achieved. Further scans showed no drop in charge collection recorded between the centre and edge pixels, with a maximum deviation of 5% in charge collection between scanned edge pixels. Scans across the cleaved and standard guard ring edges of the strip detector also show no reduction in charge collection. These results indicate techniques such as the scribe, cleave and passivate (SCP) and active edge processes offer real potential for reduced edge, tiled sensors for imaging detection applications.

  6. Direct charge sharing observation in single-photon-counting pixel detector

    NASA Astrophysics Data System (ADS)

    Pellegrini, G.; Maiorino, M.; Blanchot, G.; Chmeissani, M.; Garcia, J.; Lozano, M.; Martinez, R.; Puigdengoles, C.; Ullan, M.

    2007-04-01

    In photon-counting imaging devices, charge sharing can limit the detector spatial resolution and contrast, as multiple counts can be induced in adjacent pixels as a result of the spread of the charge cloud generated from a single X-ray photon of high energy in the detector bulk. Although debated for a long time, the full impact of charge sharing has not been completely assessed. In this work, the importance of charge sharing in pixellated CdTe and silicon detectors is studied by exposing imaging devices to different low activity sources. These devices are made of Si and CdTe pixel detector bump-bonded to Medipix2 single-photon-counting chips with a 55 μm pixel pitch. We will show how charge sharing affects the spatial detector resolution depending on incident particle type (alpha, beta and gamma), detector bias voltage and read-out chip threshold. This study will give an insight on the impact on the design and operation of pixel detectors coupled to photon-counting devices for imaging applications.

  7. HUBBLE SPACE TELESCOPE PIXEL ANALYSIS OF THE INTERACTING FACE-ON SPIRAL GALAXY NGC 5194 (M51A)

    SciTech Connect

    Lee, Joon Hyeop; Kim, Sang Chul; Park, Hong Soo; Ree, Chang Hee; Kyeong, Jaemann; Chung, Jiwon E-mail: sckim@kasi.re.kr E-mail: chr@kasi.re.kr E-mail: jiwon@kasi.re.kr

    2011-10-10

    A pixel analysis is carried out on the interacting face-on spiral galaxy NGC 5194 (M51A), using the Hubble Space Telescope (HST)/Advanced Camera for Surveys (ACS) images in the F435W, F555W, and F814W (BVI) bands. After 4 x 4 binning of the HST/ACS images to secure a sufficient signal-to-noise ratio for each pixel, we derive several quantities describing the pixel color-magnitude diagram (pCMD) of NGC 5194: blue/red color cut, red pixel sequence parameters, blue pixel sequence parameters, and blue-to-red pixel ratio. The red sequence pixels are mostly older than 1 Gyr, while the blue sequence pixels are mostly younger than 1 Gyr, in their luminosity-weighted mean stellar ages. The color variation in the red pixel sequence from V = 20 mag arcsec{sup -2} to V = 17 mag arcsec{sup -2} corresponds to a metallicity variation of {Delta}[Fe/H] {approx}2 or an optical depth variation of {Delta}{tau}{sub V} {approx} 4 by dust, but the actual sequence is thought to originate from the combination of those two effects. At V < 20 mag arcsec{sup -2}, the color variation in the blue pixel sequence corresponds to an age variation from 5 Myr to 300 Myr under the assumption of solar metallicity and {tau}{sub V} = 1. To investigate the spatial distributions of stellar populations, we divide pixel stellar populations using the pixel color-color diagram and population synthesis models. As a result, we find that the pixel population distributions across the spiral arms agree with a compressing process by spiral density waves: dense dust {yields} newly formed stars. The tidal interaction between NGC 5194 and NGC 5195 appears to enhance the star formation at the tidal bridge connecting the two galaxies. We find that the pixels corresponding to the central active galactic nucleus (AGN) area of NGC 5194 show a tight sequence at the bright-end of the pCMD, which are in the region of R {approx} 100 pc and may be a photometric indicator of AGN properties.

  8. Active millimeter-wave video rate imaging with a staring 120-element microbolometer array

    NASA Astrophysics Data System (ADS)

    Luukanen, Arttu; Miller, Aaron J.; Grossman, Erich N.

    2004-08-01

    Passive indoors imaging of weapons concealed under clothing poses a formidable challenge for millimeter-wave imagers due to the sub-picowatt signal levels present in the scene. Moreover, video-rate imaging requires a large number of pixels, which leads to a very complex and expensive front end for the imager. To meet the concealed weapons detection challenge, our approach uses a low cost pulsed-noise source as an illuminator and an array of room-temperature antenna-coupled microbolometers as the detectors. The reflected millimeter-wave power is detected by the bolometers, gated, integrated and amplified by audio-frequency amplifiers, and after digitization, displayed in real time on a PC display. We present recently acquired videos obtained with the 120-element array, and comprehensively describe the performance characteristics of the array in terms of sensitivity, optical efficiency, uniformity and spatial resolution. Our results show that active imaging with antenna-coupled microbolometers can yield imagery comparable to that obtained with systems using MMIC amplifiers but with a cost per pixel that is orders of magnitude lower.

  9. Physical activity - preventive medicine (image)

    MedlinePlus

    Physical activity contributes to health by reducing the heart rate, decreasing the risk for cardiovascular disease, and reducing the amount of bone loss that is associated with age and osteoporosis. Physical ...

  10. Active vs. inactive muscle (image)

    MedlinePlus

    ... may lose 20 to 40 percent of their muscle -- and, along with it, their strength -- as they ... have found that a major reason people lose muscle is because they stop doing everyday activities that ...

  11. High-sensitivity brain SPECT system using cadmium telluride (CdTe) semiconductor detector and 4-pixel matched collimator

    NASA Astrophysics Data System (ADS)

    Suzuki, Atsuro; Takeuchi, Wataru; Ishitsu, Takafumi; Tsuchiya, Katsutoshi; Morimoto, Yuichi; Ueno, Yuichiro; Kobashi, Keiji; Kubo, Naoki; Shiga, Tohru; Tamaki, Nagara

    2013-11-01

    For high-sensitivity brain imaging, we have developed a two-head single-photon emission computed tomography (SPECT) system using a CdTe semiconductor detector and 4-pixel matched collimator (4-PMC). The term, ‘4-PMC’ indicates that the collimator hole size is matched to a 2 × 2 array of detector pixels. By contrast, a 1-pixel matched collimator (1-PMC) is defined as a collimator whose hole size is matched to one detector pixel. The performance of the higher-sensitivity 4-PMC was experimentally compared with that of the 1-PMC. The sensitivities of the 1-PMC and 4-PMC were 70 cps/MBq/head and 220 cps/MBq/head, respectively. The SPECT system using the 4-PMC provides superior image resolution in cold and hot rods phantom with the same activity and scan time to that of the 1-PMC. In addition, with half the usual scan time the 4-PMC provides comparable image quality to that of the 1-PMC. Furthermore, 99mTc-ECD brain perfusion images of healthy volunteers obtained using the 4-PMC demonstrated acceptable image quality for clinical diagnosis. In conclusion, our CdTe SPECT system equipped with the higher-sensitivity 4-PMC can provide better spatial resolution than the 1-PMC either in half the imaging time with the same administered activity, or alternatively, in the same imaging time with half the activity.

  12. Active dictionary learning for image representation

    NASA Astrophysics Data System (ADS)

    Wu, Tong; Sarwate, Anand D.; Bajwa, Waheed U.

    2015-05-01

    Sparse representations of images in overcomplete bases (i.e., redundant dictionaries) have many applications in computer vision and image processing. Recent works have demonstrated improvements in image representations by learning a dictionary from training data instead of using a predefined one. But learning a sparsifying dictionary can be computationally expensive in the case of a massive training set. This paper proposes a new approach, termed active screening, to overcome this challenge. Active screening sequentially selects subsets of training samples using a simple heuristic and adds the selected samples to a "learning pool," which is then used to learn a newer dictionary for improved representation performance. The performance of the proposed active dictionary learning approach is evaluated through numerical experiments on real-world image data; the results of these experiments demonstrate the effectiveness of the proposed method.

  13. High accuracy injection circuit for the calibration of a large pixel sensor matrix

    NASA Astrophysics Data System (ADS)

    Quartieri, E.; Comotti, D.; Manghisoni, M.

    2013-08-01

    Semiconductor pixel detectors, for particle tracking and vertexing in high energy physics experiments as well as for X-ray imaging, in particular for synchrotron light sources and XFELs, require a large area sensor matrix. This work will discuss the design and the characterization of a high-linearity, low dispersion injection circuit to be used for pixel-level calibration of detector readout electronics in a large pixel sensor matrix. The circuit provides a useful tool for the characterization of the readout electronics of the pixel cell unit for both monolithic active pixel sensors and hybrid pixel detectors. In the latter case, the circuit allows for precise analogue test of the readout channel already at the chip level, when no sensor is connected. Moreover, it provides a simple means for calibration of readout electronics once the detector has been connected to the chip. Two injection techniques can be provided by the circuit: one for a charge sensitive amplification and the other for a transresistance readout channel. The aim of the paper is to describe the architecture and the design guidelines of the calibration circuit, which has been implemented in a 130 nm CMOS technology. Moreover, experimental results of the proposed injection circuit will be presented in terms of linearity and dispersion.

  14. A partition-based active contour model incorporating local information for image segmentation.

    PubMed

    Shi, Jiao; Wu, Jiaji; Paul, Anand; Jiao, Licheng; Gong, Maoguo

    2014-01-01

    Active contour models are always designed on the assumption that images are approximated by regions with piecewise-constant intensities. This assumption, however, cannot be satisfied when describing intensity inhomogeneous images which frequently occur in real world images and induced considerable difficulties in image segmentation. A milder assumption that the image is statistically homogeneous within different local regions may better suit real world images. By taking local image information into consideration, an enhanced active contour model is proposed to overcome difficulties caused by intensity inhomogeneity. In addition, according to curve evolution theory, only the region near contour boundaries is supposed to be evolved in each iteration. We try to detect the regions near contour boundaries adaptively for satisfying the requirement of curve evolution theory. In the proposed method, pixels within a selected region near contour boundaries have the opportunity to be updated in each iteration, which enables the contour to be evolved gradually. Experimental results on synthetic and real world images demonstrate the advantages of the proposed model when dealing with intensity inhomogeneity images.

  15. Characterization of CdTe sensors with Schottky contacts coupled to charge-integrating pixel array detectors for X-ray science

    NASA Astrophysics Data System (ADS)

    Becker, J.; Tate, M. W.; Shanks, K. S.; Philipp, H. T.; Weiss, J. T.; Purohit, P.; Chamberlain, D.; Ruff, J. P. C.; Gruner, S. M.

    2016-12-01

    Pixel Array Detectors (PADs) consist of an x-ray sensor layer bonded pixel-by-pixel to an underlying readout chip. This approach allows both the sensor and the custom pixel electronics to be tailored independently to best match the x-ray imaging requirements. Here we present characterizations of CdTe sensors hybridized with two different charge-integrating readout chips, the Keck PAD and the Mixed-Mode PAD (MM-PAD), both developed previously in our laboratory. The charge-integrating architecture of each of these PADs extends the instantaneous counting rate by many orders of magnitude beyond that obtainable with photon counting architectures. The Keck PAD chip consists of rapid, 8-frame, in-pixel storage elements with framing periods < 150 ns. The second detector, the MM-PAD, has an extended dynamic range by utilizing an in-pixel overflow counter coupled with charge removal circuitry activated at each overflow. This allows the recording of signals from the single-photon level to tens of millions of x-rays/pixel/frame while framing at 1 kHz. Both detector chips consist of a 128 × 128 pixel array with (150 μm)2 pixels.

  16. Towards spark-proof gaseous pixel detectors

    NASA Astrophysics Data System (ADS)

    Tsigaridas, S.; Beuzekom, M. v.; Chan, H. W.; Graaf, H. v. d.; Hartjes, F.; Heijhoff, K.; Hessey, N. P.; Prodanovic, V.

    2016-11-01

    The micro-pattern gaseous pixel detector, is a promising technology for imaging and particle tracking applications. It is a combination of a gas layer acting as detection medium and a CMOS pixelated readout-chip. As a prevention against discharges we deposit a protection layer on the chip and then integrate on top a micromegas-like amplification structure. With this technology we are able to reconstruct 3D track segments of particles passing through the gas thanks to the functionality of the chip. We have turned a Timepix3 chip into a gaseous pixel detector and tested it at the SPS at Cern. The preliminary results are promising and within the expectations. However, the spark protection layer needs further improvement to make reliable detectors. For this reason, we have created a setup for spark-testing. We present the first results obtained from the lab-measurements along with preliminary results from the testbeam.

  17. See around the corner using active imaging

    NASA Astrophysics Data System (ADS)

    Steinvall, Ove; Elmqvist, Magnus; Larsson, Håkan

    2011-11-01

    This paper investigates the prospects of "seeing around the corner" using active imaging. A monostatic active imaging system offers interesting capabilities in the presence of glossy reflecting objects. Examples of such surfaces are windows in buildings and cars, calm water, signs and vehicle surfaces. During daylight it might well be possible to use mirrorlike reflection by the naked eye or a CCD camera for non-line of sight imaging. However the advantage with active imaging is that one controls the illumination. This will not only allow for low light and night utilization but also for use in cases where the sun or other interfering lights limit the non-line of sight imaging possibility. The range resolution obtained by time gating will reduce disturbing direct reflections and allow simultaneous view in several directions using range discrimination. Measurements and theoretical considerations in this report support the idea of using laser to "see around the corner". Examples of images and reflectivity measurements will be presented together with examples of potential system applications.

  18. Activating Attachments Reduces Memories of Traumatic Images

    PubMed Central

    Foord, Rachael

    2016-01-01

    Emotional memories, and especially intrusive memories, are a common feature of many psychological disorders, and are overconsolidated by stress. Attachment theory posits that activation of mental representations of attachment figures can reduce stress and boost coping. This study tested the proposition that attachment activation would reduce consolidation of emotional and intrusive memories. Sixty-seven undergraduate students viewed subliminal presentations of traumatic and neutral images, which were preceded by subliminal presentations of either attachment-related images or non-attachment-related images; free recall and intrusive memories were assessed two days later. Participants with low avoidant attachment tendencies who received the attachment primes recalled fewer memories and reported fewer intrusions than those who received the non-attachment primes. Unexpectedly, those with high anxious attachment tendencies reported fewer memories. These findings generally accord with attachment theory, and suggest that consolidation of emotional memories can be moderated by activation of attachment representations. PMID:27631498

  19. MTF evaluation of white pixel sensors

    NASA Astrophysics Data System (ADS)

    Lindner, Albrecht; Atanassov, Kalin; Luo, Jiafu; Goma, Sergio

    2015-01-01

    We present a methodology to compare image sensors with traditional Bayer RGB layouts to sensors with alternative layouts containing white pixels. We focused on the sensors' resolving powers, which we measured in the form of a modulation transfer function for variations in both luma and chroma channels. We present the design of the test chart, the acquisition of images, the image analysis, and an interpretation of results. We demonstrate the approach at the example of two sensors that only differ in their color filter arrays. We confirmed that the sensor with white pixels and the corresponding demosaicing result in a higher resolving power in the luma channel, but a lower resolving power in the chroma channels when compared to the traditional Bayer sensor.

  20. Active confocal imaging for visual prostheses.

    PubMed

    Jung, Jae-Hyun; Aloni, Doron; Yitzhaky, Yitzhak; Peli, Eli

    2015-06-01

    There are encouraging advances in prosthetic vision for the blind, including retinal and cortical implants, and other "sensory substitution devices" that use tactile or electrical stimulation. However, they all have low resolution, limited visual field, and can display only few gray levels (limited dynamic range), severely restricting their utility. To overcome these limitations, image processing or the imaging system could emphasize objects of interest and suppress the background clutter. We propose an active confocal imaging system based on light-field technology that will enable a blind user of any visual prosthesis to efficiently scan, focus on, and "see" only an object of interest while suppressing interference from background clutter. The system captures three-dimensional scene information using a light-field sensor and displays only an in