Science.gov

Sample records for active region design

  1. Active-region designs in quantum cascade lasers

    SciTech Connect

    Zasavitskii, I I

    2012-10-31

    This paper analyses the development of active-region designs in quantum cascade lasers. Active-region designs have been demonstrated to date that employ various radiative transitions (vertical, diagonal, interminiband and interband). The lower laser level is depopulated through nonradiative transitions, such as one- or two-phonon (and even three-phonon) relaxation or bound state {yields} continuum transitions. Advances in active-region designs and energy diagram optimisation in the past few years have led to significant improvements in important characteristics of quantum cascade lasers, such as their output power, emission bandwidth, characteristic temperature and efficiency. (invited paper)

  2. On the modified active region design of interband cascade lasers

    SciTech Connect

    Motyka, M.; Ryczko, K.; Dyksik, M.; Sęk, G.; Misiewicz, J.; Weih, R.; Dallner, M.; Kamp, M.; Höfling, S.

    2015-02-28

    Type II InAs/GaInSb quantum wells (QWs) grown on GaSb or InAs substrates and designed to be integrated in the active region of interband cascade lasers (ICLs) emitting in the mid infrared have been investigated. Optical spectroscopy, combined with band structure calculations, has been used to probe their electronic properties. A design with multiple InAs QWs has been compared with the more common double W-shaped QW and it has been demonstrated that it allows red shifting the emission wavelength and enhancing the transition oscillator strength. This can be beneficial for the improvements of the ICLs performances, especially when considering their long-wavelength operation.

  3. Design of plasmonic photodetector with high absorptance and nano-scale active regions.

    PubMed

    Guo, Jingshu; Wu, Zhiwei; Li, Yuan; Zhao, Yanli

    2016-08-01

    We propose a novel plasmonic photodetector with high responsivity, utilizing nano-scale active regions. This design can be applied to diverse materials (group III-V or IV materials) and different operation wavelengths covering the O-U bands. The periodic structure utilizing Surface Plasmon Polariton Bloch Waves (SPP-BWs) has low optical power loss. FDTD simulation shows an absorptance of 74.4% which means a responsivity of about 0.74 A/W at 1550 nm. The low capacitance brings low noise, reduced power consumption, and a high electrical bandwidth which is estimated to be 140 GHz. Among the plasmonic PDs with inherent high speeds but low responsivities, our design makes the obvious progress on improving the absorptance. PMID:27505787

  4. Broadly continuously tunable slot waveguide quantum cascade lasers based on a continuum-to-continuum active region design

    SciTech Connect

    Meng, Bo; Zeng, Yong Quan; Liang, Guozhen; Hu, Xiao Nan; Rodriguez, Etienne; Wang, Qi Jie

    2015-09-14

    We report our progress in the development of broadly tunable single-mode slot waveguide quantum cascade lasers based on a continuum-to-continuum active region design. The electroluminescence spectrum of the continuum-to-continuum active region design has a full width at half maximum of 440 cm{sup −1} at center wavelength ∼10 μm at room temperature (300 K). Devices using the optimized slot waveguide structure and the continuum-to-continuum design can be tuned continuously with a lasing emission over 42 cm{sup −1}, from 9.74 to 10.16 μm, at room temperature by using only current tuning scheme, together with a side mode suppression ratio of above 15 dB within the whole tuning range.

  5. Active region seismology

    NASA Technical Reports Server (NTRS)

    Bogdan, Tom; Braun, D. C.

    1995-01-01

    Active region seismology is concerned with the determination and interpretation of the interaction of the solar acoustic oscillations with near-surface target structures, such as magnetic flux concentration, sunspots, and plage. Recent observations made with a high spatial resolution and a long temporal duration enabled measurements of the scattering matrix for sunspots and solar active regions to be carried out as a function of the mode properties. Based on this information, the amount of p-mode absorption, partial-wave phase shift, and mode mixing introduced by the sunspot, could be determined. In addition, the possibility of detecting the presence of completely submerged magnetic fields was raised, and new procedures for performing acoustic holography of the solar interior are being developed. The accumulating evidence points to the mode conversion of p-modes to various magneto-atmospheric waves within the magnetic flux concentration as being the unifying physical mechanism responsible for these diverse phenomena.

  6. Active region flows

    NASA Technical Reports Server (NTRS)

    Foukal, Peter

    1987-01-01

    A wide range of observations has shown that active region phenomena in the photospheric, chromospheric and coronal temperature regimes are dynamical in nature. At the photosphere, recent observations of full line profiles place an upper limit of about + or - 20/msec on any downflows at supergranule cell edges. Observations of the full Stokes 5 profiles in the network show no evidence for downflows in magnetic flux tubes. In the area of chromospheric dynamics, several models were put forward recently to reproduce the observed behavior of spicules. However, it is pointed out that these adiabatic models do not include the powerful radiative dissipation which tend to damp out the large amplitude disturbances that produce the spicular acceleration in the models. In the corona, loop flows along field lines clearly transport mass and energy at rates important for the dynamics of these structures. However, advances in understanding the heating and mass balance of the loop structures seem to require new kinds of observations. Some results are presented using a remote sensing diagnostic of the intensity and orientation of macroscopic plasma electric fields predicted by models of reconnective heating and also wave heating.

  7. Regional Activities Division. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    Papers on library network activities in Canada, the Third World, Japan, Malaysia, Brazil, and Sweden which were presented at the 1982 International Federation of Library Associations (IFLA) conference include: (1) "Canada: A Voluntary and Flexible Network," a review by Guy Sylvestre of the political, social, and economic structures affecting…

  8. Regional Changes in Word-Production Laterality after a Naming Treatment Designed to Produce a Rightward Shift in Frontal Activity

    ERIC Educational Resources Information Center

    Crosson, Bruce; Moore, Anna Bacon; McGregor, Keith M.; Chang, Yu-Ling; Benjamin, Michelle; Gopinath, Kaundinya; Sherod, Megan E.; Wierenga, Christina E.; Peck, Kyung K.; Briggs, Richard W.; Rothi, Leslie J. Gonzalez; White, Keith D.

    2009-01-01

    Five nonfluent aphasia patients participated in a picture-naming treatment that used an intention manipulation (opening a box and pressing a button on a device in the box with the left hand) to initiate naming trials and was designed to re-lateralize word production mechanisms from the left to the right frontal lobe. To test the underlying…

  9. Active Region Release Two CMEs

    NASA Video Gallery

    Solar material can be seen blowing off the sun in this video captured by NASA’s Solar Dynamics Observatory (SDO) on the night of Feb. 5, 2013. This active region on the sun sent out two coronal ...

  10. Effect of the design of the active region of monolithic multi-color LED heterostructures on their spectra and emission efficiency

    SciTech Connect

    Tsatsulnikov, A. F. Lundin, W. V.; Sakharov, A. V.; Zavarin, E. E.; Usov, S. O.; Nikolaev, A. E.; Sinitsyn, M. A.; Cherkashin, N. A.; Karpov, S. Y.

    2015-11-15

    The design features of light-emitting-diode heterostructures with a monolithic InGaN/GaN active region containing several InGaN quantum wells (QWs) emitting at different wavelengths, grown by metal-organic chemical vapor deposition, are studied. It is shown that the number of emission bands can be raised to three by increasing the number of deposited InGaN QWs with different indium contents. The emission efficiency decreases by approximately 30% with increasing number of QWs at high currents. The dependences of the optical properties of the heterostructures on the number of QWs and types of barriers between the QWs (GaN layer or InGaN/GaN short-period superlattice) are analyzed. It is demonstrated that the ratio between the intensities of the emission lines widely varies with current flowing through the structure and greatly depends on the type and width of the barriers between the QWs.

  11. SDO Sees Active Region Outbursts

    NASA Video Gallery

    This close up video by NASA’s Solar Dynamics Observatory shows an active region near the right-hand edge of the sun’s disk, which erupted with at least a dozen minor events over a 30-hour period fr...

  12. Ab Initio Active Region Formation

    NASA Astrophysics Data System (ADS)

    Stein, Robert F.; Nordlund, A.

    2013-01-01

    The tachocline is not necessary to produce active regions with their global properties. Dynamo action within the convection zone can produce large scale reversing polarity magnetic fields as shown by ASH code and Charboneau et al simulations. Magneto-convection acting on this large scale field produces Omega-loops which emerge through the surface to produce active regions. The field first emerges as small bipoles with horizontal field over granules anchored in vertical fields in the intergranular lanes. The fields are quickly swept into the intergranular lanes and produce a mixed polarity "pepper and salt" pattern. The opposite polarities then migrate toward separate unipolar regions due to the underlying large scale loop structure. When sufficient flux concentrates, pores and sunspots form. We will show movies of magneto-convection simulations of the emerging flux, its migration, and concentration to form pores and spots, as well as the underlying magnetic field evolution. In addition, the same atmospheric data has been used as input to the LILIA Stokes Inversion code to calculate Stokes spectra for the Fe I 630 nm lines and then invert them to determine the magnetic field. Comparisons of the inverted field with the simulation field shows that small-scale, weak fields, less than 100 G, can not be accurately determined because of vertical gradients that are difficult to match in fitting the line profiles. Horizontal smoothing by telescope diffraction further degrades the inversion accuracy.

  13. Biourbanism: Solar based urban and regional design

    SciTech Connect

    Williams, D.

    1999-07-01

    New neighborhoods for an additional one billion people will need to be constructed on the planet within the next 10 years. If the historic patterns of growth continue--the sprawl, the congestion, the draining of swamps, the loss of agricultural land--the requirement for all basic resources will outstrip the availability. While this is of great concern, it is the destruction of an acceptable quality of life--the sense of place--that will be the most difficult and expensive to change. An essential step to reverse the direction of this undesirable future is changing the design and planning of these communities to work with resident solar energies, regional biology, local renewable resources, and sustainable urban planning and design principles. Design can make a difference. This paper develops the view that the solar approach must include urban and regional design and presents solar-based renewable resources example of the design of regions.

  14. Design and comparison of GaAs, GaAsP and InGaAlAs quantum-well active regions for 808-nm VCSELs.

    PubMed

    Zhang, Yan; Ning, Yongqiang; Zhang, Lisen; Zhang, Jinsheng; Zhang, Jianwei; Wang, Zhenfu; Zhang, Jian; Zeng, Yugang; Wang, Lijun

    2011-06-20

    Vertical-cavity surface-emitting lasers emitting at 808 nm with unstrained GaAs/Al0.3Ga0.7As, tensilely strained GaAs(x)P(1-x)/Al0.3Ga0.7As and compressively strained In(1-x-y)Ga(x)Al(y)As/Al0.3Ga0.7As quantum-well active regions have been investigated. A comprehensive model is presented to determine the composition and width of these quantum wells. The numerical simulation shows that the gain peak wavelength is near 800 nm at room temperature for GaAs well with width of 4 nm, GaAs0.87P0.13 well with width of 13 nm and In0.14Ga0.74Al0.12As well with width of 6 nm. Furthermore, the output characteristics of the three designed quantum-well VCSELs are studied and compared. The results indicate that In0.14Ga0.74Al0.12As is the most appropriate candidate for the quantum well of 808-nm VCSELs.

  15. Solar active region display system

    NASA Astrophysics Data System (ADS)

    Golightly, M.; Raben, V.; Weyland, M.

    2003-04-01

    The Solar Active Region Display System (SARDS) is a client-server application that automatically collects a wide range of solar data and displays it in a format easy for users to assimilate and interpret. Users can rapidly identify active regions of interest or concern from color-coded indicators that visually summarize each region's size, magnetic configuration, recent growth history, and recent flare and CME production. The active region information can be overlaid onto solar maps, multiple solar images, and solar difference images in orthographic, Mercator or cylindrical equidistant projections. Near real-time graphs display the GOES soft and hard x-ray flux, flare events, and daily F10.7 value as a function of time; color-coded indicators show current trends in soft x-ray flux, flare temperature, daily F10.7 flux, and x-ray flare occurrence. Through a separate window up to 4 real-time or static graphs can simultaneously display values of KP, AP, daily F10.7 flux, GOES soft and hard x-ray flux, GOES >10 and >100 MeV proton flux, and Thule neutron monitor count rate. Climatologic displays use color-valued cells to show F10.7 and AP values as a function of Carrington/Bartel's rotation sequences - this format allows users to detect recurrent patterns in solar and geomagnetic activity as well as variations in activity levels over multiple solar cycles. Users can customize many of the display and graph features; all displays can be printed or copied to the system's clipboard for "pasting" into other applications. The system obtains and stores space weather data and images from sources such as the NOAA Space Environment Center, NOAA National Geophysical Data Center, the joint ESA/NASA SOHO spacecraft, and the Kitt Peak National Solar Observatory, and can be extended to include other data series and image sources. Data and images retrieved from the system's database are converted to XML and transported from a central server using HTTP and SOAP protocols, allowing

  16. Conceptual Design of a Regional Information System.

    ERIC Educational Resources Information Center

    Denver Regional Council of Governments, CO.

    This report describes the conceptual design of a regional information system, developed in support of the Denver Regional Council of Government's established comprehensive planning work program. It includes a discussion of system objectives, available data sources, recommended system content, software and system maintenance requirements,…

  17. Design Activity Framework for Visualization Design.

    PubMed

    McKenna, Sean; Mazur, Dominika; Agutter, James; Meyer, Miriah

    2014-12-01

    An important aspect in visualization design is the connection between what a designer does and the decisions the designer makes. Existing design process models, however, do not explicitly link back to models for visualization design decisions. We bridge this gap by introducing the design activity framework, a process model that explicitly connects to the nested model, a well-known visualization design decision model. The framework includes four overlapping activities that characterize the design process, with each activity explicating outcomes related to the nested model. Additionally, we describe and characterize a list of exemplar methods and how they overlap among these activities. The design activity framework is the result of reflective discussions from a collaboration on a visualization redesign project, the details of which we describe to ground the framework in a real-world design process. Lastly, from this redesign project we provide several research outcomes in the domain of cybersecurity, including an extended data abstraction and rich opportunities for future visualization research. PMID:26356933

  18. Design Activity Framework for Visualization Design.

    PubMed

    McKenna, Sean; Mazur, Dominika; Agutter, James; Meyer, Miriah

    2014-12-01

    An important aspect in visualization design is the connection between what a designer does and the decisions the designer makes. Existing design process models, however, do not explicitly link back to models for visualization design decisions. We bridge this gap by introducing the design activity framework, a process model that explicitly connects to the nested model, a well-known visualization design decision model. The framework includes four overlapping activities that characterize the design process, with each activity explicating outcomes related to the nested model. Additionally, we describe and characterize a list of exemplar methods and how they overlap among these activities. The design activity framework is the result of reflective discussions from a collaboration on a visualization redesign project, the details of which we describe to ground the framework in a real-world design process. Lastly, from this redesign project we provide several research outcomes in the domain of cybersecurity, including an extended data abstraction and rich opportunities for future visualization research.

  19. What makes active regions grow.

    NASA Technical Reports Server (NTRS)

    Weart, S.

    1972-01-01

    A study of magnetic flux growth or growth failure in over 100 active regions is shown to indicate that most growth is connected with the emergence of a large batch of flux in the shape of a new arch filament system (AFS). During the recent sunspot maximum, new AFSs appeared at a rate of nearly one per day over the entire sun. Evidence is presented for two proposed hypotheses, namely: (1) a twist in the flux tubes of new AFSs is a key factor in determining which new AFSs will grow; and (2) this twist is related to the well-known asymmetry of sunspot groups.

  20. Cometary nucleus and active regions

    NASA Technical Reports Server (NTRS)

    Whipple, F. L.

    1984-01-01

    On the basis of the icy conglomerate model of cometary nuclei, various observations demonstrate the spotted nature of many or most nuclei, i.e., regions of unusual activity, either high or low. Rotation periods, spin axes and even precession of the axes are determined. The observational evidence for variations in activity over the surfaces of cometary nuclei are listed and discussed. On June 11 the comet IRAS-ARAKI-ALCOCK approached the Earth to a distance of 0.031 AU, the nearest since C/Lexell, 1770 I, providing a unique opportunity for near-nucleus observations. Preliminary analysis of these images establishes the spin axis of the nucleus, with an oblioquity to the orbit plane of approximately 50 deg, and a lag angle of sublimation approximately 35 deg from the solar meridian on the nucleus. Asymmetries of the inner coma suggests a crazy-quilt distribution of ices with differing volatility over the surface of the nucleus. The observations of Comet P/Homes 1892 III, exhibiting two 8-10 magnitude bursts, are carefully analyzed. The grazing encounter produced, besides the first great burst, an active area on the nucleus, which was rotating retrograde with a period of 16.3hr and inclination nearly 180 deg. After the first burst the total magnitude fell less than two magnitudes from November 7 to November 30 (barely naked eye) while the nuclear region remained diffuse or complex, rarely if ever showing a stellar appearance. The fading was much more rapid after the second burst. The grazing encounter distributed a volume of large chunks in the neighborhood of the nucleus, maintaining activity for weeks.

  1. Evolution of active region outflows throughout an active region lifetime

    NASA Astrophysics Data System (ADS)

    Zangrilli, L.; Poletto, G.

    2016-10-01

    Context. We have shown previously that SOHO/UVCS data allow us to detect active region (AR) outflows at coronal altitudes higher than those reached by other instrumentation. These outflows are thought to be a component of the slow solar wind. Aims: Our purpose is to study the evolution of the outflows in the intermediate corona from AR 8100, from the time the AR first forms until it dissolves, after several transits at the solar limb. Methods: Data acquired by SOHO/UVCS at the time of the AR limb transits, at medium latitudes and at altitudes ranging from 1.5 to 2.3 R⊙, were used to infer the physical properties of the outflows through the AR evolution. To this end, we applied the Doppler dimming technique to UVCS spectra. These spectra include the H i Lyα line and the O vi doublet lines at 1031.9 and 1037.6 Å. Results: Plasma speeds and electron densities of the outflows were inferred over several rotations of the Sun. AR outflows are present in the newly born AR and persist throughout the entire AR life. Moreover, we found two types of outflows at different latitudes, both possibly originating in the same negative polarity area of the AR. We also analyzed the behavior of the Si xii 520 Å line along the UVCS slit in an attempt to reveal changes in the Si abundance when different regions are traversed. Although we found some evidence for a Si enrichment in the AR outflows, alternative interpretations are also plausible. Conclusions: Our results demonstrate that outflows from ARs are detectable in the intermediate corona throughout the whole AR lifetime. This confirms that outflows contribute to the slow wind.

  2. Effects of active region design on gain and carrier injection and transport of CW (20\\bar{2}\\bar{1}) semipolar InGaN laser diodes

    NASA Astrophysics Data System (ADS)

    Becerra, Daniel L.; Cohen, Daniel A.; Farrell, Robert M.; DenBaars, Steven P.; Nakamura, Shuji

    2016-09-01

    High-power CW semipolar (20\\bar{2}\\bar{1}) laser diodes (LDs) were studied. Improved efficiencies (threshold, differential, and wall plug) were observed when the number of quantum wells (QWs) in the active region was reduced from 4 to 2. Threshold current densities as low as 2.6 kA/cm2 were obtained. The differential efficiency of a 5 µm wide by 1200 µm long LD with a 2-QW active region was 54% and the wall plug efficiency was 11%. Experimental and analytical analyses of the devices suggested carrier leakage from an ineffective electron-blocking layer, providing an explanation for the high voltage observed in all the devices.

  3. Emission measure distribution for diffuse regions in solar active regions

    SciTech Connect

    Subramanian, Srividya; Tripathi, Durgesh; Klimchuk, James A.; Mason, Helen E.

    2014-11-01

    Our knowledge of the diffuse emission that encompasses active regions is very limited. In this paper we investigate two off-limb active regions, namely, AR 10939 and AR 10961, to probe the underlying heating mechanisms. For this purpose, we have used spectral observations from Hinode/EIS and employed the emission measure (EM) technique to obtain the thermal structure of these diffuse regions. Our results show that the characteristic EM distributions of the diffuse emission regions peak at log T = 6.25 and the coolward slopes are in the range 1.4-3.3. This suggests that both low- as well as high-frequency nanoflare heating events are at work. Our results provide additional constraints on the properties of these diffuse emission regions and their contribution to the background/foreground when active region cores are observed on-disk.

  4. CME Productivity of Active Regions.

    NASA Astrophysics Data System (ADS)

    Liu, L.; Wang, Y.; Wang, J.; Shen, C.; Ye, P.; Zhang, Q.; Liu, R.; Wang, S.

    2015-12-01

    Solar active regions (ARs) are the major sources of two kinds of the most violent solar eruptions, namely flares and coronal mass ejections (CMEs). Although they are believed to be two phenomena in the same eruptive process, the productivity of them could be quiet different for various ARs. Why is an AR productive? And why is a flare-rich AR CME-poor? To answer these questions, we compared the recent super flare-rich but CME-poor AR 12192, with other four ARs; two were productive in both flares and CMEs and the other two were inert to produce any M-class or intenser flares or CMEs. By investigating the photospheric parameters based on the SDO/HMI vector magnetogram, we find the three productive ARs have larger magnetic flux, current and free magnetic energy than the inert ARs. Furthermore, the two ARs productive in both flares and CMEs contain higher current helicity, concentrating along both sides of the flaring neutral lines, indicating the presence of a seed magnetic structure( that is highly sheared or twisted) of a CME; they also have higher decay index in the low corona, showing weak constraint. The results suggest that productive ARs are always large and have strong current system and sufficient free energy to power flares, and more importantly whether or not a flare is accompanied by a CME is seemingly related to (1) if there is significant sheared or twisted core field serving as the seed of the CME and (2) if the constraint of the overlying arcades is weak enough. Moreover, some productive ARs may frequently produce more than one CME. How does this happen? We do a statistical investigation of waiting times of quasi-homologous CMEs ( CME ssuccessive originating from the same ARs within short intervals) from super ARs in solar cycle 23 to answer this question. The waiting times of quasi-homologous CMEs have a two-component distribution with a separation at about 18 hours, the first component peaks at 7 hours. The correlation analysis among CME waiting times

  5. B-Factory Interaction Region Design

    NASA Astrophysics Data System (ADS)

    Sullivan, M.

    1997-05-01

    High luminosity B factories are generally high current (1-3 A) e^+e^- storage ring accelerators that operate at a center-of-mass energy equal to the mass of the Υ4S resonance (10.58 GeV). The high beam currents are achieved by storing a large number of bunches (several hundred to several thousand) into each beam. Two designs, the ones located at SLAC and KEK, also have asymmetric beam energies. This imparts a boost to the nearly stationary B mesons formed from the decay of the Υ4S and allows precision vertex tracking detectors to look for a difference between the decay profiles of the matter and anti-matter B mesons thereby observing a violation of CP. Bringing these stored beams into collision is one of the major challenges of any B factory design. In order to achieve high luminosity the beams must be tightly focused. This pushes the final focusing elements close enough to the interaction point to be inside the solenoidal field of the physics detector. In addition, beam related detector backgrounds from synchrotron radiation and scattered beam particles must be kept below an acceptable level. The major B factory designs at Cornell University, KEK, and SLAC have all addressed these problems in various ways that depend on specific accelerator design decisions. This presentation will describe the accelerator choices that affect the interaction region design of a B factory and discuss how the above designs address the challenges posed by a high luminosity B factory.

  6. The Main Sequence of Explosive Solar Active Regions: Comparison of Emerging and Mature Active Regions

    NASA Technical Reports Server (NTRS)

    Falconer, David; Moore, Ron

    2011-01-01

    For mature active regions, an active region s magnetic flux content determines the maximum free energy the active region can have. Most Large flares and CMEs occur in active regions that are near their free-energy limit. Active-region flare power radiated in the GOES 1-8 band increases steeply as the free-energy limit is approached. We infer that the free-energy limit is set by the rate of release of an active region s free magnetic energy by flares, CMEs and coronal heating balancing the maximum rate the Sun can put free energy into the active region s magnetic field. This balance of maximum power results in explosive active regions residing in a "mainsequence" in active-region (flux content, free energy content) phase space, which sequence is analogous to the main sequence of hydrogen-burning stars in (mass, luminosity) phase space.

  7. onHigh-peak-power strain-compensated GaInAs/AlInAs quantum cascade lasers (λ ˜4.6 μm) based on a slightly diagonal active region design

    NASA Astrophysics Data System (ADS)

    Yang, Q.; Lösch, R.; Bronner, W.; Hugger, S.; Fuchs, F.; Aidam, R.; Wagner, J.

    2008-12-01

    Employing a "slightly diagonal" active region design for the quantum cascade lasers compared to a reference sample based on the conventional vertical transition design [R. Köhler et al., Appl. Phys. Lett. 76, 1092 (2000)], we have improved the maximum operation temperature, room-temperature maximum peak power per facet, and room-temperature slope efficiency from 320 K, 200 mW, and 570 mW/A to higher than 360 K, 3.2 W, and 2200 mW/A, respectively, for the device size of 16 μm×3 mm with as-cleaved facets operated in pulsed mode.

  8. A Case of Filament - Active Region Interaction

    NASA Astrophysics Data System (ADS)

    Dumitrache, C.; Dumitru, L.

    2010-09-01

    We analyze a huge filament observed between 5 and 19 September 2001. In its evolution it is linked to the active region 9612, observed between 7 and 16 September 2001. The filament has a strange morphology and dynamics: starting as two parallel components (A and B), it becomes a double sigmoid filament when a third component (C ) appears linking the other two. An unusual magnetic topology characterizes this evolution: the active region is located between the parallel components. When the third component becomes observable, it links these ones first below the active region. After a spectacular plasma movement registered in filament (A), this one becomes linked to (B) above the active region. In spite of these dramatically changes of the magnetic topology and filament -- active region switch, no CME is observed. Only a few flares occurring in AR9612 are registered and these ones can be seen in the dynamics of the filament as an expression of large scale magnetic reconnections.

  9. Regional hyperthermia applicator design using FDTD modelling.

    PubMed

    Kroeze, H; Van de Kamer, J B; De Leeuw, A A; Lagendijk, J J

    2001-07-01

    Recently published results confirm the positive effect of regional hyperthermia combined with external radiotherapy on pelvic tumours. Several studies have been published on the improvement of RF annular array applicator systems with dipoles and a closed water bolus. This study investigates the performance of a next-generation applicator system for regional hyperthermia with a multi-ring annular array of antennas and an open water bolus. A cavity slot antenna is introduced to enhance the directivity and reduce mutual coupling between the antennas. Several design parameters, i.e. dimensions, number of antennas and operating frequency, have been evaluated using several patient models. Performance indices have been defined to evaluate the effect of parameter variation on the specific absorption rate (SAR) distribution. The performance of the new applicator type is compared with the Coaxial TEM. Operating frequency appears to be the main parameter with a positive influence on the performance. A SAR increase in tumour of 1.7 relative to the Coaxial TEM system can be obtained with a three-ring, six-antenna per ring cavity slot applicator operating at 150 MHz. PMID:11474934

  10. Regional hyperthermia applicator design using FDTD modelling.

    PubMed

    Kroeze, H; Van de Kamer, J B; De Leeuw, A A; Lagendijk, J J

    2001-07-01

    Recently published results confirm the positive effect of regional hyperthermia combined with external radiotherapy on pelvic tumours. Several studies have been published on the improvement of RF annular array applicator systems with dipoles and a closed water bolus. This study investigates the performance of a next-generation applicator system for regional hyperthermia with a multi-ring annular array of antennas and an open water bolus. A cavity slot antenna is introduced to enhance the directivity and reduce mutual coupling between the antennas. Several design parameters, i.e. dimensions, number of antennas and operating frequency, have been evaluated using several patient models. Performance indices have been defined to evaluate the effect of parameter variation on the specific absorption rate (SAR) distribution. The performance of the new applicator type is compared with the Coaxial TEM. Operating frequency appears to be the main parameter with a positive influence on the performance. A SAR increase in tumour of 1.7 relative to the Coaxial TEM system can be obtained with a three-ring, six-antenna per ring cavity slot applicator operating at 150 MHz.

  11. Southern Regional Center for Lightweight Innovative Design

    SciTech Connect

    Wang, Paul T.

    2012-12-01

    The Southern Regional Center for Lightweight Innovative Design (SRCLID) has developed an experimentally validated cradle-to-grave modeling and simulation effort to optimize automotive components in order to decrease weight and cost, yet increase performance and safety in crash scenarios. In summary, the three major objectives of this project are accomplished: To develop experimentally validated cradle-to-grave modeling and simulation tools to optimize automotive and truck components for lightweighting materials (aluminum, steel, and Mg alloys and polymer-based composites) with consideration of uncertainty to decrease weight and cost, yet increase the performance and safety in impact scenarios; To develop multiscale computational models that quantify microstructure-property relations by evaluating various length scales, from the atomic through component levels, for each step of the manufacturing process for vehicles; and To develop an integrated K-12 educational program to educate students on lightweighting designs and impact scenarios. In this final report, we divided the content into two parts: the first part contains the development of building blocks for the project, including materials and process models, process-structure-property (PSP) relationship, and experimental validation capabilities; the second part presents the demonstration task for Mg front-end work associated with USAMP projects.

  12. Design: a voice activated thermostat.

    PubMed

    Jacobson, S

    1992-01-01

    The voice activated thermostat was designed so the temperature in a house could be set without having to touch the thermostat. This is especially useful for a quadriplegic who would like to change the temperature of the room he is in. For simplicity, it was designed using VCP200 speaker-independent word recognizer chip. This chip comes pre-programmed with a limited number of words, so programming of words was not necessary. Every time the activation word is said the digital thermostat changes by one degree.

  13. Suppression of Active-Region CME Production by the Presence of Other Active Regions

    NASA Technical Reports Server (NTRS)

    Falconer, David; Moore, Ron; Barghouty, Abdulnasser; Khazanov, Igor

    2009-01-01

    From the SOHO mission s data base of MDI full-disk magnetograms spanning solar cycle 23, we have obtained a set of 40,000 magnetograms of 1,300 active regions, tracking each active region across the 30 degree central solar disk. Each active region magnetogram is cropped from the full-disk magnetogram by an automated code. The cadence is 96 minutes. From each active-region magnetogram, we have measured two whole-active-region magnetic quantities: (1) the magnetic size of the active region (the active region s total magnetic flux), and (2) a gauge of the active region s free magnetic energy (part of the free energy is released in the production of a flare and/or CME eruption). From NOAA Flare/CME catalogs, we have obtained the event (Flare/CME/SEP event) production history of each active region. Using all these data, we find that for each type of eruptive event, an active region s expected rate of event production increases as a power law of our gauge of active-region free magnetic energy. We have also found that, among active regions having nearly the same free energy, the rate of the CME production is less when there are many other active regions on the disk than when there are few or none, but there is no significant discernible suppression of the rate of flare production. This indicates that the presence of other active regions somehow tends to inhibit an active region s flare-producing magnetic explosions from becoming CMEs, contrary to the expectation from the breakout model for the production of CMEs.

  14. Active Region Emergence and Remote Flares

    NASA Astrophysics Data System (ADS)

    Fu, Yixing; Welsch, Brian T.

    2016-02-01

    We study the effect of new emerging solar active regions on the large-scale magnetic environment of existing regions. We first present a theoretical approach to quantify the "interaction energy" between new and pre-existing regions as the difference between i) the summed magnetic energies of their individual potential fields and ii) the energy of their superposed potential fields. We expect that this interaction energy can, depending upon the relative arrangements of newly emerged and pre-existing magnetic flux, indicate the existence of "topological" free magnetic energy in the global coronal field that is independent of any "internal" free magnetic energy due to coronal electric currents flowing within the newly emerged and pre-existing flux systems. We then examine the interaction energy in two well-studied cases of flux emergence, but find that the predicted energetic perturbation is relatively small compared to energies released in large solar flares. Next, we present an observational study of the influence of the emergence of new active regions on flare statistics in pre-existing active regions, using NOAA's Solar Region Summary and GOES flare databases. As part of an effort to precisely determine the emergence time of active regions in a large event sample, we find that emergence in about half of these regions exhibits a two-stage behavior, with an initial gradual phase followed by a more rapid phase. Regarding flaring, we find that the emergence of new regions is associated with a significant increase in the occurrence rate of X- and M-class flares in pre-existing regions. This effect tends to be more significant when pre-existing and new emerging active regions are closer. Given the relative weakness of the interaction energy, this effect suggests that perturbations in the large-scale magnetic field, such as topology changes invoked in the "breakout" model of coronal mass ejections, might play a significant role in the occurrence of some flares.

  15. Hinode Captures Images of Solar Active Region

    NASA Video Gallery

    In these images, Hinode's Solar Optical Telescope (SOT) zoomed in on AR 11263 on August 4, 2011, five days before the active region produced the largest flare of this cycle, an X6.9. We show images...

  16. Polar Field Reversals and Active Region Decay

    NASA Astrophysics Data System (ADS)

    Petrie, Gordon; Ettinger, Sophie

    2015-07-01

    We study the relationship between polar field reversals and decayed active region magnetic flux. Photospheric active region flux is dispersed by differential rotation and turbulent diffusion, and is transported poleward by meridional flows and diffusion. We summarize the published evidence from observation and modeling of the influence of meridional flow variations and decaying active region flux's spatial distribution, such as the Joy's law tilt angle. Using NSO Kitt Peak synoptic magnetograms covering cycles 21-24, we investigate in detail the relationship between the transport of decayed active region flux to high latitudes and changes in the polar field strength, including reversals in the magnetic polarity at the poles. By means of stack plots of low- and high-latitude slices of the synoptic magnetograms, the dispersal of flux from low to high latitudes is tracked, and the timing of this dispersal is compared to the polar field changes. In the most abrupt cases of polar field reversal, a few activity complexes (systems of active regions) are identified as the main cause. The poleward transport of large quantities of decayed trailing-polarity flux from these complexes is found to correlate well in time with the abrupt polar field changes. In each case, significant latitudinal displacements were found between the positive and negative flux centroids of the complexes, consistent with Joy's law bipole tilt with trailing-polarity flux located poleward of leading-polarity flux. The activity complexes of the cycle 21 and 22 maxima were larger and longer-lived than those of the cycle 23 and 24 maxima, and the poleward surges were stronger and more unipolar and the polar field changes larger and faster. The cycle 21 and 22 polar reversals were dominated by only a few long-lived complexes whereas the cycle 23 and 24 reversals were the cumulative effects of more numerous, shorter-lived regions. We conclude that sizes and lifetimes of activity complexes are key to

  17. The 17 GHz active region number

    SciTech Connect

    Selhorst, C. L.; Pacini, A. A.; Costa, J. E. R.; Giménez de Castro, C. G.; Valio, A.; Shibasaki, K.

    2014-08-01

    We report the statistics of the number of active regions (NAR) observed at 17 GHz with the Nobeyama Radioheliograph between 1992, near the maximum of cycle 22, and 2013, which also includes the maximum of cycle 24, and we compare with other activity indexes. We find that NAR minima are shorter than those of the sunspot number (SSN) and radio flux at 10.7 cm (F10.7). This shorter NAR minima could reflect the presence of active regions generated by faint magnetic fields or spotless regions, which were a considerable fraction of the counted active regions. The ratio between the solar radio indexes F10.7/NAR shows a similar reduction during the two minima analyzed, which contrasts with the increase of the ratio of both radio indexes in relation to the SSN during the minimum of cycle 23-24. These results indicate that the radio indexes are more sensitive to weaker magnetic fields than those necessary to form sunspots, of the order of 1500 G. The analysis of the monthly averages of the active region brightness temperatures shows that its long-term variation mimics the solar cycle; however, due to the gyro-resonance emission, a great number of intense spikes are observed in the maximum temperature study. The decrease in the number of these spikes is also evident during the current cycle 24, a consequence of the sunspot magnetic field weakening in the last few years.

  18. IS ACTIVE REGION CORE VARIABILITY AGE DEPENDENT?

    SciTech Connect

    Ugarte-Urra, Ignacio; Warren, Harry P.

    2012-12-10

    The presence of both steady and transient loops in active region cores has been reported from soft X-ray and extreme-ultraviolet observations of the solar corona. The relationship between the different loop populations, however, remains an open question. We present an investigation of the short-term variability of loops in the core of two active regions in the context of their long-term evolution. We take advantage of the nearly full Sun observations of STEREO and Solar Dynamics Observatory spacecraft to track these active regions as they rotate around the Sun multiple times. We then diagnose the variability of the active region cores at several instances of their lifetime using EIS/Hinode spectral capabilities. We inspect a broad range of temperatures, including for the first time spatially and temporally resolved images of Ca XIV and Ca XV lines. We find that the active region cores become fainter and steadier with time. The significant emission measure at high temperatures that is not correlated with a comparable increase at low temperatures suggests that high-frequency heating is viable. The presence, however, during the early stages, of an enhanced emission measure in the ''hot'' (3.0-4.5 MK) and ''cool'' (0.6-0.9 MK) components suggests that low-frequency heating also plays a significant role. Our results explain why there have been recent studies supporting both heating scenarios.

  19. Organized Subsurface Flows near Active Regions

    NASA Astrophysics Data System (ADS)

    Haber, D. A.; Hindman, B. W.; Toomre, J.; Thompson, M. J.

    2004-04-01

    Local helioseismic techniques, such as ring analysis and time-distance helioseismology, have already shown that large-scale flows near the surface converge towards major active regions. Ring analysis has further demonstrated that at greater depths some active regions exhibit strong outflows. A critique leveled at the ring-analysis results is that the Regularized Least Squares (RLS) inversion kernels on which they are based have negative sidelobes near the surface. Such sidelobes could result in a surface inflow being misidentified as a diverging outflow at depth. In this paper we show that the Optimally Located Averages (OLA) inversion technique, which produces kernels without significant sidelobes, generates flows markedly similar to the RLS results. Active regions are universally zones of convergence near the surface, while large complexes evince strong outflows deeper down.

  20. The Magnetic Free Energy in Active Regions

    NASA Technical Reports Server (NTRS)

    Metcalf, Thomas R.; Mickey, Donald L.; LaBonte, Barry J.

    2001-01-01

    The magnetic field permeating the solar atmosphere governs much of the structure, morphology, brightness, and dynamics observed on the Sun. The magnetic field, especially in active regions, is thought to provide the power for energetic events in the solar corona, such as solar flares and Coronal Mass Ejections (CME) and is believed to energize the hot coronal plasma seen in extreme ultraviolet or X-rays. The question remains what specific aspect of the magnetic flux governs the observed variability. To directly understand the role of the magnetic field in energizing the solar corona, it is necessary to measure the free magnetic energy available in active regions. The grant now expiring has demonstrated a new and valuable technique for observing the magnetic free energy in active regions as a function of time.

  1. ON THE FORMATION OF ACTIVE REGIONS

    SciTech Connect

    Stein, Robert F.; Nordlund, Ake E-mail: aake@nbi.dk

    2012-07-01

    Magnetoconvection can produce an active region without an initial coherent flux tube. A simulation was performed where a uniform, untwisted, horizontal magnetic field of 1 kG strength was advected into the bottom of a computational domain 48 Mm wide by 20 Mm deep. The up and down convective motions produce a hierarchy of magnetic loops with a wide range of scales, with smaller loops riding 'piggy-back' in a serpentine fashion on larger loops. When a large loop approaches the surface, it produces a small active region with a compact leading spot and more diffuse following spots.

  2. Polar Field Reversals and Active Region Decay

    NASA Astrophysics Data System (ADS)

    Petrie, Gordon; Ettinger, Sophie

    2015-04-01

    We study the relationship between polar field reversals and decayed active region magnetic flux. Photospheric active region flux is dispersed by differential rotation and turbulent diffusion, and is transported poleward by meridional flows and diffusion. Using NSO Kitt Peak synoptic magnetograms, we investigate in detail the relationship between the transport of decayed active region flux to high latitudes and changes in the polar field strength, including reversals in the magnetic polarity at the poles. By means of stack plots of low- and high-latitude slices of the synoptic magnetograms, the dispersal of flux from low to high latitudes is tracked, and the timing of this dispersal is compared to the polar field changes. In the most abrupt cases of polar field reversal, a few activity complexes (systems of active regions) are identified as the main cause. The poleward transport of large quantities of decayed lagging-polarity flux from these complexes is found to correlate well in time with the abrupt polar field changes. In each case, significant latitudinal displacements were found between the positive and negative flux centroids of the complexes, consistent with Joy's law bipole tilt with lagging-polarity flux located poleward of leading-polarity flux. This work is carried out through the National Solar Observatory Summer Research Assistantship (SRA) Program. The National Solar Observatory is operated by the Association of Universities for Research in Astronomy, Inc. (AURA) under cooperative agreement with the National Science Foundation.

  3. Solar Eruptions Initiated in Sigmoidal Active Regions

    NASA Astrophysics Data System (ADS)

    Savcheva, Antonia

    2016-07-01

    active regions that have been shown to possess high probability for eruption. They present a direct evidence of the existence of flux ropes in the corona prior to the impulsive phase of eruptions. In order to gain insight into their eruptive behavior and how they get destabilized we need to know their 3D magnetic field structure. First, we review some recent observations and modeling of sigmoidal active regions as the primary hosts of solar eruptions, which can also be used as useful laboratories for studying these phenomena. Then, we concentrate on the analysis of observations and highly data-constrained non-linear force-free field (NLFFF) models over the lifetime of several sigmoidal active regions, where we have captured their magnetic field structure around the times of major flares. We present the topology analysis of a couple of sigmoidal regions pointing us to the probable sites of reconnection. A scenario for eruption is put forward by this analysis. We demonstrate the use of this topology analysis to reconcile the observed eruption features with the standard flare model. Finally, we show a glimpse of how such a NLFFF model of an erupting region can be used to initiate a CME in a global MHD code in an unprecedented realistic manner. Such simulations can show the effects of solar transients on the near-Earth environment and solar system space weather.

  4. Interface Intermixing in Type II InAs/GaInAsSb Quantum Wells Designed for Active Regions of Mid-Infrared-Emitting Interband Cascade Lasers.

    PubMed

    Motyka, Marcin; Sęk, Grzegorz; Ryczko, Krzysztof; Dyksik, Mateusz; Weih, Robert; Patriarche, Gilles; Misiewicz, Jan; Kamp, Martin; Höfling, Sven

    2015-12-01

    The effect of interface intermixing in W-design GaSb/AlSb/InAs/Ga0.665In0.335AsxSb1 - x/InAs/AlSb/GaSb quantum wells (QWs) has been investigated by means of optical spectroscopy supported by structural data and by band structure calculations. The fundamental optical transition has been detected at room temperature through photoluminescence and photoreflectance measurements and appeared to be blueshifted with increasing As content of the GaInAsSb layer, in contrast to the energy-gap-driven shifts calculated for an ideally rectangular QW profile. The arsenic incorporation into the hole-confining layer affects the material and optical structure also altering the InAs/GaInAsSb interfaces and their degree of intermixing. Based on the analysis of cross-sectional transmission electron microscopy images and energy-dispersive X-ray spectroscopy, we could deduce the composition distribution across the QW layers and hence simulate more realistic confinement potential profiles. For such smoothed interfaces that indicate As-enhanced intermixing, the energy level calculations have been able to reproduce the experimentally obtained trend.

  5. Asia Section. Regional Activities Division. Paper.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    Two papers on library and information activities in developing nations, particularly in India and other Asian countries, were presented at the 1983 International Federation of Library Associations (IFLA) conference. In "IFLA in Asia: A Review of the Work of the Regional Section for Asia," Edward Lim Huck Tee (Malaysia) describes the low level of…

  6. TRACE Observations of Active Region Births

    NASA Astrophysics Data System (ADS)

    Wolfson, C. J.; Shine, R. A.

    2000-05-01

    TRACE has recorded the births of a few bona-fide active regions, as well as many ephemeral regions and so-called X-ray bright points. The observations have usually been made serendipitously while studying a nearby, well formed active region. However, a couple of events have been recorded when deliberately looking for emerging flux in quiet portions of an active region belt. This poster will discuss some of the best observations to date, where the quality ranking of the observation is closely coupled to the observing mode TRACE was in and the availability of high resolution (temporal and/or spatial) MDI magnetograms. Included will be the birth of NOAA AR#8699 on 11 September 1999 at about 14 UT (N22E34), AR#8637 on 17 July 1999 at about 4 UT (N11W1), and AR#8885 on 21 February 2000 at about 6 UT (N11W7); these specifics being provided to encourage coordination with other observations. The temporal relationships between the first appearances of magnetic bipoles, EUV loops, chromospheric plage, pores, and sunspots will be discussed as will the growth rate and spatial relationships of these different features and any associated photospheric flows.

  7. Silicon on insulator with active buried regions

    DOEpatents

    McCarthy, Anthony M.

    1998-06-02

    A method for forming patterned buried components, such as collectors, sources and drains, in silicon-on-insulator (SOI) devices. The method is carried out by epitaxially growing a suitable sequence of single or multiple etch stop layers ending with a thin silicon layer on a silicon substrate, masking the silicon such that the desired pattern is exposed, introducing dopant and activating in the thin silicon layer to form doped regions. Then, bonding the silicon layer to an insulator substrate, and removing the silicon substrate. The method additionally involves forming electrical contact regions in the thin silicon layer for the buried collectors.

  8. Silicon on insulator with active buried regions

    DOEpatents

    McCarthy, A.M.

    1996-01-30

    A method is disclosed for forming patterned buried components, such as collectors, sources and drains, in silicon-on-insulator (SOI) devices. The method is carried out by epitaxially growing a suitable sequence of single or multiple etch stop layers ending with a thin silicon layer on a silicon substrate, masking the silicon such that the desired pattern is exposed, introducing dopant and activating in the thin silicon layer to form doped regions. Then, bonding the silicon layer to an insulator substrate, and removing the silicon substrate. The method additionally involves forming electrical contact regions in the thin silicon layer for the buried collectors. 10 figs.

  9. Silicon on insulator with active buried regions

    DOEpatents

    McCarthy, A.M.

    1998-06-02

    A method is disclosed for forming patterned buried components, such as collectors, sources and drains, in silicon-on-insulator (SOI) devices. The method is carried out by epitaxially growing a suitable sequence of single or multiple etch stop layers ending with a thin silicon layer on a silicon substrate, masking the silicon such that the desired pattern is exposed, introducing dopant and activating in the thin silicon layer to form doped regions. Then, bonding the silicon layer to an insulator substrate, and removing the silicon substrate. The method additionally involves forming electrical contact regions in the thin silicon layer for the buried collectors. 10 figs.

  10. Silicon on insulator with active buried regions

    DOEpatents

    McCarthy, Anthony M.

    1996-01-01

    A method for forming patterned buried components, such as collectors, sources and drains, in silicon-on-insulator (SOI) devices. The method is carried out by epitaxially growing a suitable sequence of single or multiple etch stop layers ending with a thin silicon layer on a silicon substrate, masking the silicon such that the desired pattern is exposed, introducing dopant and activating in the thin silicon layer to form doped regions. Then, bonding the silicon layer to an insulator substrate, and removing the silicon substrate. The method additionally involves forming electrical contact regions in the thin silicon layer for the buried collectors.

  11. Magnetic helicity in emerging solar active regions

    SciTech Connect

    Liu, Y.; Hoeksema, J. T.; Bobra, M.; Hayashi, K.; Sun, X.; Schuck, P. W.

    2014-04-10

    Using vector magnetic field data from the Helioseismic and Magnetic Imager instrument aboard the Solar Dynamics Observatory, we study magnetic helicity injection into the corona in emerging active regions (ARs) and examine the hemispheric helicity rule. In every region studied, photospheric shearing motion contributes most of the helicity accumulated in the corona. In a sample of 28 emerging ARs, 17 follow the hemisphere rule (61% ± 18% at a 95% confidence interval). Magnetic helicity and twist in 25 ARs (89% ± 11%) have the same sign. The maximum magnetic twist, which depends on the size of an AR, is inferred in a sample of 23 emerging ARs with a bipolar magnetic field configuration.

  12. Supergranule Diffusion and Active Region Decay

    NASA Technical Reports Server (NTRS)

    Hathaway, David H.; Choudhary, Debi Prasad

    2004-01-01

    Models of the Sun's magnetic dynamo include turbulent diffusion to parameterize the effects of convective motions on the evolution of the Sun's magnetic field. Supergranules are known to dominate the evolution of the surface magnetic field structure as evidenced by the structure of both the active and quiet magnetic network. However, estimates for the dif hivity attributed to su perymules differ by an order of magnitude from about 100 km sup2/s to more than 1000 km sup2/s. We examine this question of the e i v i t y using three merent approaches. 1) We study the decay of more than 30,000 active regions by determining the rate of change in the sunspot area of each active region from day-to-day. 2) We study the decay of a single isolated active region near the time of solar minimum by examining the magnetic field evolution over five solar rotations fiom SOHOMDI magnetograms obtained at 96-minute intervals. 3) We study the characteristics of supergranules that influence the estimates of their diffusive properties - flow speeds and lifetimes as functions of size - fiom SOHO/MDI Dopplergrams.

  13. Active region evolution in the chromosphere and transtition region

    NASA Technical Reports Server (NTRS)

    Shine, R. A.; Schrijver, C. J.

    1988-01-01

    Images in the C IV 1548 A and the Si II 1526 S lines taken with the ultraviolet spectrometer polarimeter (UVSP) instrument on board the Solar Maximum Mission (SMM) satellite were combined into movies showing the evolution of active regions and the neighboring supergranulation over several days. The data sets generally consist of 240 by 240 arc second rasters with 3 arc second pixels taken one per orbit (about every 90 minutes). The images are projected on a latitude/longitude grid to remove the forshortening as the region rotates across the solar disk and further processed to remove jitter and gain variations. Movies were made with and without differential rotation. Although there are occasional missing orbits, these series do not suffer from the long nighttime gaps that occur in observations taken at a single groundbased observatory and are excellent for studying changes on time scales of several hours. The longest sequence processed to date runs from 20 Oct. 1980 to 25 Oct. 1980. This was taken during an SMM flare buildup study on AR 2744. Several shorter sequences taken in 1980 and 1984 will also be shown. The results will be presented on a video disk which can be interactively controlled to view the movies.

  14. Solar luminosity fluctuations and active region photometry

    SciTech Connect

    Chapman, G.A.; Herzog, A.D.; Lawrence, J.K.; Shelton, J.C.

    1984-07-15

    We present monochromatic observations, obtained with a 512 element diode array, of the irradiance fluctuations of the sunspots and faculae of an active region during its disk transit in 1982 August. Bolometric and stray light corrections are approximately equal in magnitude but opposite in sign, so they have not been applied. The maximum sunspot fluctuation, as a fraction of the quiet-Sun irradiance, is -800 parts per million (ppm). Faculae have a maximum irradiance fluctuation of about +200 ppm near the limbs. We find that the facular energy excess is more than 50% of the sunspot energy deficit, which is -5.8 x 10/sup 35/ ergs. These observations show that faculae are an important element in active region energy balance.

  15. Analysis of body calcium (regional changes in body calcium by in vivo neutron activation analysis)

    NASA Technical Reports Server (NTRS)

    Suki, W.; Johnson, P. C.; Leblanc, A.; Evans, H. J.

    1981-01-01

    The effect of space flight on urine and fecal calcium loss was documented during the three long-term Skylab flights. Neutron activation analysis was used to determine regional calcium loss. Various designs for regional analysis were investigated.

  16. Southern Regional Center for Lightweight Innovative Design

    SciTech Connect

    Horstemeyer, Mark F.; Wang, Paul

    2011-12-27

    The three major objectives of this Phase III project are: To develop experimentally validated cradle-to-grave modeling and simulation tools to optimize automotive and truck components for lightweighting materials (aluminum, steel, and Mg alloys and polymer-based composites) with consideration of uncertainty to decrease weight and cost, yet increase the performance and safety in impact scenarios; To develop multiscale computational models that quantify microstructure-property relations by evaluating various length scales, from the atomic through component levels, for each step of the manufacturing process for vehicles; and To develop an integrated K-12 educational program to educate students on lightweighting designs and impact scenarios.

  17. Integrated design focus of regional MRF

    SciTech Connect

    McAdams, C.L.

    1995-03-01

    In November 1993, construction began on a 1,020-tpd mixed waste materials recovery facility (MRF) that will serve the counties of Bladen, Cumberland, and Hoke in North Carolina. In addition to being a regional MRF, the facility has also drawn distinction because of the 900-tpd waste-to-energy (WTE) facility it will feed. The entire project is a unique combination of facilities creating an integrated system featuring recycling and energy recovery from waste. When fully operational, the MRF is expected to recover 25% of incoming waste for recycling. Because of the low capital costs of the project, the participating communities will have the lowest cost solution to recycling and waste disposal for many centuries to come.

  18. Design of the advanced regional aircraft, the DART-75

    NASA Technical Reports Server (NTRS)

    Elliott, Steve; Gislason, Jason; Huffstetler, Mark; Mann, Jon; Withers, Ashley; Zimmerman, Mark

    1992-01-01

    This design analysis is intended to show the capabilities of the DART-75, a 75 passenger medium-range regional transport. Included are the detailed descriptions of the structures, performance, stability and control, weight and balance, and engine design. The design should allow for the DART to become the premier regional aircraft of the future due to some advanced features like the canard, semi-composite construction, and advanced engines.

  19. Axial Tilt Angles of Active Regions

    NASA Astrophysics Data System (ADS)

    Howard, Robert F.

    1996-12-01

    Separate Mount Wilson plage and sunspot group data sets are analyzed in this review to illustrate several interesting aspects of active region axial tilt angles. (1) The distribution of tilt angles differs between plages and sunspot groups in the sense that plages have slightly higher tilt angles, on average, than do spot groups. (2) The distributions of average plage total magnetic flux, or sunspot group area, with tilt angle show a consistent effect: those groups with tilt angles nearest the average values are larger (or have a greater total flux) on average than those farther from the average values. Moreover, the average tilt angles on which these size or flux distributions are centered differ for the two types of objects, and represent closely the actual different average tilt angles for these two features. (3) The polarity separation distances of plages and sunspot groups show a clear relationship to average tilt angles. In the case of each feature, smaller polarity separations are correlated with smaller tilt angles. (4) The dynamics of regions also show a clear relationship with region tilt angles. The spot groups with tilt angles nearest the average value (or perhaps 0-deg tilt angle) have on average a faster rotation rate than those groups with extreme tilt angles. All of these tilt-angle characteristics may be assumed to be related to the physical forces that affect the magnetic flux loop that forms the region. These aspects are discussed in this brief review within the context of our current view of the formation of active region magnetic flux at the solar surface.

  20. Assessing design activity in complex CMOS circuit design

    NASA Astrophysics Data System (ADS)

    Biswas, Gautam; Goldman, Susan R.; Fisher, Doug; Bhuva, Bharat; Glewwe, Grant

    1994-03-01

    This chapter characterizes human problem solving in digital circuit design. We analyze protocols of designers with varying degrees of training, identifying problem solving strategies used by these designers, discuss activity patterns that differentiate designers, and propose these as a tentative basis for assessing expertise in digital design. Throughout, we argue that a comprehensive model of human design should integrate a variety of strategies, which heretofore have been proposed as individually sufficient models of human design problem solving. We close by describing an automated tool for design and its assessment.

  1. Solar irradiance variations due to active regions

    SciTech Connect

    Oster, L.; Schatten, K.H.; Sofia, S.

    1982-05-15

    We have been able to reproduce the variations of the solar irradiance observed by ACRIM to an accuracy of better than +- 0.4 W m/sup -2/, assuming that during the 6 month observation period in 1980 the solar luminosity was constant. The improvement over previous attempts is primarily due to the inclusion of faculae. The reproduction scheme uses simple geometrical data on spot and facula areas, and conventional parameters for the respective fluxes and angular dependencies. The quality of reproduction is not very sensitive to most of the details of these parameters; nevertheless, there conventional parameters cannot be very different from their actual values in the solar atmosphere. It is interesting that the time average of the integrated excess emission (over directions) of the faculae cancels out the integrated deficit produced by the spots, within an accuracy of about 10%. If this behavior were maintained over longer periods of time, say, on the order of an activity cycle, active regions could be viewed as a kind of lighthouse where the energy deficit near the normal direction, associated with the spots, is primarily reemitted close to the tangential directions by the faculae. The currently available data suggest that energy ''storage'' associated with the redirection of flux near active regions on the Sun is comparable to the lifetime of the faculae.

  2. Footpoint Separation and Evershed Flow of Active Regions

    NASA Astrophysics Data System (ADS)

    Norton, Aimee Ann; Jones, E. H.

    2012-05-01

    The bipolar nature of active regions and sunspot groups within the Sun’s photosphere is generally attributed to the emergence of magnetic flux tubes that originate from shear and turbulent pumping at the base of the Sun’s convection zone. There is debate, however, as to exactly how well-connected active regions are to solar interior. A connection to the solar interior during the ascent of a flux tube through the convection zone is a requirement within numerical models designed to describe the observed characteristics of active regions, e.g. Joy’s law tilt and latitude emergence, however, these models also predict post-emergence behavior of sunspots that is not supported observationally (Schussler and Rempel, 1995; Fan, 2009; Toth and Gerlei, 2003). It has been suggested (Rubio et al., 2008; Schussler and Rempel, 1995) that a bipolar magnetic region might lose its connection quickly upon emergence. Using data from SDO/HMI, we examine the footpoint separation and the Evershed flow of a number of active regions over time to detect the disconnection process of a sunspot from its magnetic roots.

  3. Observations of an active region filament

    NASA Astrophysics Data System (ADS)

    Zong, W. G.; Tang, Y. H.; Fang, C.; Xu, A. A.

    An active region filament was well observed on September 4, 2002 with THEMIS at the Teide observatory and SOHO/MDI. The full Stokes parameters of the filament were obtained in Hα and FeI 6302 Å lines. Using the data, we have studied the fine structure of the filament and obtained the parameters at the barb endpoints, including intensity, velocity and longitudinal magnetic field. Our results indicate: (a) the Doppler velocities are quiet different at barb endpoints; (b) the longitudinal magnetic fields at the barb endpoints are very weak; (c) there is a strong magnetic field structure under the filament spine.

  4. Pederson Current Dissipation In Emerging Active Regions

    NASA Astrophysics Data System (ADS)

    Leake, James E.; Linton, M. G.

    2011-05-01

    Pederson current dissipation in emerging active regions. Certain regions of the solar atmosphere, such as the photosphere and chromosphere, as well as prominences, contain a significant amount of neutral atoms, and a complete description of the plasma requires including the effects of partial ionization. In the chromosphere the dissipation of Pederson currents is important for the evolution of emerging magnetic fields. Due to the relatively high number density in the chromosphere, the ion-neutral collision time-scale is much smaller than timescales associated with flux emergence. Hence we use a single-fluid approach to model the partially ionized plasma. Looking at both the emergence of large-scale sub-surface structures, and the emergence and reconnection of undulatory fields, we investigate the effect of Pederson current dissipation on the state of the emerging field, on magnetic reconnection and on dissipative heating of the atmosphere. Specifically we examine the effect of motions across fieldlines in the partially ionized regions, and how this can increase the free energy supplied to the corona by flux emergence. We also look at reconnection associated with flux emergence in the partially ionized atmosphere, and how this can account for observed small-scale brightenings (Ellerman Bombs).

  5. Designing for the Active Classroom

    SciTech Connect

    Wilkerson, Andrea M.; Donohue, Amy; Davis, Robert G.

    2015-02-01

    The article discusses trends in classroom design and then transitions to a discussion of the future of the classroom and how the lighting industry needs to be preparing to meet the needs of the future classroom. The OSU Classroom building as an example throughout, first discussing how trends in classroom design were incorporated into the Classroom Building and then discussing how future lighting systems could enhance the Classroom Building, which is a clear departure from the actual lighting design and current technology.

  6. HEROES Observations of a Quiescent Active Region

    NASA Astrophysics Data System (ADS)

    Shih, A. Y.; Christe, S.; Gaskin, J.; Wilson-Hodge, C.

    2014-12-01

    Hard X-ray (HXR) observations of solar flares reveal the signatures of energetic electrons, and HXR images with high dynamic range and high sensitivity can distinguish between where electrons are accelerated and where they stop. Even in the non-flaring corona, high-sensitivity HXR measurements may be able to detect the presence of electron acceleration. The High Energy Replicated Optics to Explore the Sun (HEROES) balloon mission added the capability of solar observations to an existing astrophysics balloon payload, HERO, which used grazing-incidence optics for direct HXR imaging. HEROES measures HXR emission from ~20 to ~75 keV with an angular resolution of 33" HPD. HEROES launched on 2013 September 21 from Fort Sumner, New Mexico, and had a successful one-day flight. We present the detailed analysis of the 7-hour observation of AR 11850, which sets new upper limits on the HXR emission from a quiescent active region, with corresponding constraints on the numbers of tens of keV energetic electrons present. Using the imaging capability of HEROES, HXR upper limits are also obtained for the quiet Sun surrounding the active region. We also discuss what can be achieved with new and improved HXR instrumentation on balloons.

  7. Cereal Box Design: An Interdisciplinary Graphics Activity

    ERIC Educational Resources Information Center

    Fitzgerald, Mike; Tsosie, Teri

    2004-01-01

    This article describes cereal box design, an interdisciplinary graphics activity. The cereal box design activity is intriguing both for its simplicity and the resourcefulness that it can generate in young people. It lends itself to a variety of curriculums. It covers both consumerism and Design for the Environment (DfE) concepts broadly and in…

  8. TARPs: Tracked Active Region Patches from SoHO/MDI

    NASA Astrophysics Data System (ADS)

    Turmon, M.; Hoeksema, J. T.; Bobra, M.

    2013-12-01

    We describe progress toward creating a retrospective MDI data product consisting of tracked magnetic features on the scale of solar active regions, abbreviated TARPs (Tracked Active Region Patches). The TARPs are being developed as a backward-looking extension (covering approximately 3500 regions spanning 1996-2010) to the HARP (HMI Active Region Patch) data product that has already been released for HMI (2010-present). Like the HARPs, the MDI TARP data set is designed to be a catalog of active regions (ARs), indexed by a region ID number, analogous to a NOAA AR number, and time. TARPs from MDI are computed based on the 96-minute synoptic magnetograms and pseudo-continuum intensitygrams. As with the related HARP data product, the approximate threshold for significance is 100G. Use of both image types together allows faculae and sunspots to be separated out as sub-classes of activity, in addition to identifying the overall active region that the faculae/sunspots are part of. After being identified in single images, the magnetically-active patches are grouped and tracked from image to image. Merges among growing active regions, as well as faint active regions hovering at the threshold of detection, are handled automatically. Regions are tracked from their inception until they decay within view, or transit off the visible disk. The final data product is indexed by a nominal AR number and time. For each active region and for each time, a bitmap image is stored containing the precise outline of the active region. Additionaly, metadata such as areas and integrated fluxes are stored for each AR and for each time. Because there is a calibration between the HMI and MDI magnetograms (Liu, Hoeksema et al. 2012), it is straightforward to use the same classification and tracking rules for the HARPs (from HMI) and the MDI TARPs. We anticipate that this will allow a consistent catalog spanning both instruments. We envision several uses for the TARP data product, which will be

  9. FIP bias in a sigmoidal active region

    NASA Astrophysics Data System (ADS)

    Baker, D.; Brooks, D. H.; Démoulin, P.; van Driel-Gesztelyi, Lidia; Green, L. M.; Steed, K.; Carlyle, J.

    2014-01-01

    We investigate first ionization potential (FIP) bias levels in an anemone active region (AR) - coronal hole (CH) complex using an abundance map derived from Hinode/EIS spectra. The detailed, spatially resolved abundance map has a large field of view covering 359'' × 485''. Plasma with high FIP bias, or coronal abundances, is concentrated at the footpoints of the AR loops whereas the surrounding CH has a low FIP bias, ~1, i.e. photospheric abundances. A channel of low FIP bias is located along the AR's main polarity inversion line containing a filament where ongoing flux cancellation is observed, indicating a bald patch magnetic topology characteristic of a sigmoid/flux rope configuration.

  10. A theoretical approach to spot active regions in antimicrobial proteins

    PubMed Central

    2009-01-01

    Background Much effort goes into identifying new antimicrobial compounds able to evade the increasing resistance of microorganisms to antibiotics. One strategy relies on antimicrobial peptides, either derived from fragments released by proteolytic cleavage of proteins or designed from known antimicrobial protein regions. Results To identify these antimicrobial determinants, we developed a theoretical approach that predicts antimicrobial proteins from their amino acid sequence in addition to determining their antimicrobial regions. A bactericidal propensity index has been calculated for each amino acid, using the experimental data reported from a high-throughput screening assay as reference. Scanning profiles were performed for protein sequences and potentially active stretches were identified by the best selected threshold parameters. The method was corroborated against positive and negative datasets. This successful approach means that we can spot active sequences previously reported in the literature from experimental data for most of the antimicrobial proteins examined. Conclusion The method presented can correctly identify antimicrobial proteins with an accuracy of 85% and a sensitivity of 90%. The method can also predict their key active regions, making this a tool for the design of new antimicrobial drugs. PMID:19906288

  11. Three dimensional structures of solar active regions

    NASA Technical Reports Server (NTRS)

    Kundu, M. R.

    1986-01-01

    Three dimensional structure of an active region is determined from observations with the Very Large Array (VLA) at 2, 6, and 20 cm. This region exhibits a single magnetic loop of length approx. 10 to the 10th power cm. The 2 cm radiation is mostly thermal bremsstrahlung and originates from the footpoints of the loop. The 6 and 20 cm radiation is dominated by the low harmonic gyroresonance radiation and originates from the upper portion of the legs or the top of the loop. The loop broadens toward the apex. The top of the loop is not found to be the hottest point, but two temperature maxima on either side of the loop apex are observed, which is consistent with the model proposed for long loops. From 2 and 6 cm observations it can be concluded that the electron density and temperature cannot be uniform in a plane perpendicular to the axis of the loop; the density should decrease away from the axis of the loop.

  12. Multiple Wavelength Observations of Flaring Active Regions

    NASA Astrophysics Data System (ADS)

    Lang, Kenneth R.

    The radio emission of quiescent active regions at 6 cm wavelength marks the legs of magnetic dipoles, and the emission at 20 cm wavelength delineates the radio wavelength counterpart of the coronal loops previously detected at X-ray wavelengths. At both wavelengths the temperatures have coronal values of a few million degrees. The polarization of the radio emission specifies the structure and strength of the coronal magnetic field (H ≈ 600 Gauss at heights h ≈ 4 x 109 cm above sunspot umbrae). At 6 cm and 20 cm wavelength the solar bursts have angular sizes between 5" and 30", brightness temperatures between 2 x 107 K and 2 x 108 K, and degrees of circular polarization between 10% and 90%. The location of the burst energy release is specified with second-of-arc accuracy. At radio wavelengths the bursts occur within the central regions of magnetic loops, while the flaring Ha kernels are located at the loop footpoints. Coronal loops exhibit enhanced radio emission (preburst heating) a few minutes before the release of burst energy. The radio polarization data indicate magnetic changes before and during solar bursts.

  13. Designing Instructional Activities for Young Handicapped Children.

    ERIC Educational Resources Information Center

    Kaczmarek, Louise A.; Dell, Amy Glasser

    1981-01-01

    Proposed are several new directions that encourage the variety and flexibility of haphazard teaching and the precision of one objective-one activity teaching in the design of activities for handicapped preschoolers. Journal availability: see EC 133 846. (Author)

  14. Design of the advanced regional aircraft, the DART-75

    NASA Technical Reports Server (NTRS)

    Elliot, Steve; Gislason, Jason; Huffstetler, Mark; Mann, Jon; Withers, Ashley; Zimmerman, Mark

    1992-01-01

    The need for regional aircraft stems from the problem of hub airport congestion. Regional travel will allow a passenger to commute from one spoke city to another spoke city without entering the congested hub airport. In addition, those people traveling longer routes may begin the flight at home instead of traveling to the hub airport. At this time, there is no American aerospace company that produces a regional transport for under 100 passengers. The intention of the Developmental Advanced Regional Transport (DART-75) is to fill this void with a modern, efficient regional aircraft. This design achieves the efficiency through a number of advanced features including three lifting surfaces, partial composite construction, and an advanced engine design. Efficiency is not the only consideration. Structural integrity, fatigue life, ease of maintenance, passenger comfort and convenience, and environmental aspects must all be considered. These factors force the design team to face many tradeoffs that are studied to find the best solution. The final consideration that cannot be overlooked is that of cost. The DART-75 is a 75-passenger medium-range regional transport intended for spoke-to-spoke, spoke-to-hub, and some hub-to-hub operations. Included are the general descriptions of the structures, weight and balance, stability and control, performance, and engine design.

  15. Cereal Box Design: An Interdisciplinary Graphics Activity

    ERIC Educational Resources Information Center

    Fitzgerald, Mike; Tsosie, Teri

    2012-01-01

    The cereal box design activity is intriguing both for its simplicity and the resourcefulness that it can generate in young people. Also, it lends itself to a variety of curriculums. It covers both consumerism and Design for the Environment (DfE) concepts broadly and in depth. The activity introduces a wide range of topics. They include graphic…

  16. The Life Cycle of Active Region Magnetic Fields

    NASA Astrophysics Data System (ADS)

    Cheung, M. C. M.; van Driel-Gesztelyi, L.; Martínez Pillet, V.; Thompson, M. J.

    2016-08-01

    We present a contemporary view of how solar active region magnetic fields are understood to be generated, transported and dispersed. Empirical trends of active region properties that guide model development are discussed. Physical principles considered important for active region evolution are introduced and advances in modeling are reviewed.

  17. MAGNETIC ENERGY SPECTRA IN SOLAR ACTIVE REGIONS

    SciTech Connect

    Abramenko, Valentyna; Yurchyshyn, Vasyl

    2010-09-01

    Line-of-sight magnetograms for 217 active regions (ARs) with different flare rates observed at the solar disk center from 1997 January until 2006 December are utilized to study the turbulence regime and its relationship to flare productivity. Data from the SOHO/MDI instrument recorded in the high-resolution mode and data from the BBSO magnetograph were used. The turbulence regime was probed via magnetic energy spectra and magnetic dissipation spectra. We found steeper energy spectra for ARs with higher flare productivity. We also report that both the power index, {alpha}, of the energy spectrum, E(k) {approx} k{sup -}{alpha}, and the total spectral energy, W = {integral}E(k)dk, are comparably correlated with the flare index, A, of an AR. The correlations are found to be stronger than those found between the flare index and the total unsigned flux. The flare index for an AR can be estimated based on measurements of {alpha} and W as A = 10{sup b}({alpha}W){sup c}, with b = -7.92 {+-} 0.58 and c = 1.85 {+-} 0.13. We found that the regime of the fully developed turbulence occurs in decaying ARs and in emerging ARs (at the very early stage of emergence). Well-developed ARs display underdeveloped turbulence with strong magnetic dissipation at all scales.

  18. Quasi-active suspension design using magnetorheological dampers

    NASA Astrophysics Data System (ADS)

    Potter, Jack N.; Neild, Simon A.; Wagg, David J.

    2011-05-01

    Quasi-active damping is a method of coupled mechanical and control system design using multiple semi-active dampers. By designing the systems such that the desired control force may always be achieved using a combination of the dampers, quasi-active damping seeks to approach levels of vibration isolation achievable through active damping, whilst retaining the desirable attributes of semi-active systems. In this article a design is proposed for a quasi-active, base-isolating suspension system. Control laws are firstly defined in a generalised form, where semi-active dampers are considered as idealised variable viscous dampers. This system is used to demonstrate in detail the principles of quasi-active damping, in particular the necessary interaction between mechanical and control systems. It is shown how such a system can produce a tunable, quasi-active region in the frequency response of very low displacement transmissibility. Quasi-active control laws are then proposed which are specific for use with magnetorheological dampers. These are validated in simulation using a realistic model of the damper dynamics, again producing a quasi-active region in the frequency response. Finally, the robustness of the magnetorheological, quasi-active suspension system is demonstrated.

  19. Symmetric Achromatic Low-Beta Collider Interaction Region Design Concept

    SciTech Connect

    Morozov, Vasiliy S.; Derbenev, Yaroslav S.; Lin, Fanglei; Johnson, Rolland P.

    2013-01-01

    We present a new symmetry-based concept for an achromatic low-beta collider interaction region design. A specially-designed symmetric Chromaticity Compensation Block (CCB) induces an angle spread in the passing beam such that it cancels the chromatic kick of the final focusing quadrupoles. Two such CCB?s placed symmetrically around an interaction point allow simultaneous compensation of the 1st-order chromaticities and chromatic beam smear at the IP without inducing significant 2nd-order aberrations. We first develop an analytic description of this approach and explicitly formulate 2nd-order aberration compensation conditions at the interaction point. The concept is next applied to develop an interaction region design for the ion collider ring of an electron-ion collider. We numerically evaluate performance of the design in terms of momentum acceptance and dynamic aperture. The advantages of the new concept are illustrated by comparing it to the conventional distributed-sextupole chromaticity compensation scheme.

  20. Active magnetic bearings for optimum turbomachinery design

    NASA Technical Reports Server (NTRS)

    Hustak, J.; Kirk, R. G.; Schoeneck, K. A.

    1985-01-01

    The design and shop test results are given for a high speed eight stage centrifugal compressor supported by active magnetic bearings. A brief summary of the rotor dynamics analysis is presented with specific attention given to design considerations for optimum rotor stability. The concerns for retrofit of magnetic bearings in existing machinery are discussed with supporting analysis of a four stage centrifugal compressor. Recommendations are given on design and analysis requirements for successful machinery operation of either retrofit or new design turbomachinery.

  1. Substrate-emitting semiconductor laser with a trapezoidal active region

    SciTech Connect

    Dikareva, N V; Nekorkin, S M; Karzanova, M V; Zvonkov, B N; Aleshkin, V Ya; Dubinov, A A; Afonenko, A A

    2014-04-28

    Semiconductor lasers with a narrow (∼2°) directional pattern in the planes both parallel and perpendicular to the p–n junction are fabricated. To achieve a low radiation divergence in the p–n junction plane, the active region in this plane was designed in the form of a trapezium. The narrow directional pattern in the plane perpendicular to the p–n junction was ensured by the use of a leaky mode, through which more than 90% of laser power was coupled out. (lasers)

  2. The First Structure–Activity Relationship Studies for Designer Receptors Exclusively Activated by Designer Drugs

    PubMed Central

    2016-01-01

    Over the past decade, two independent technologies have emerged and been widely adopted by the neuroscience community for remotely controlling neuronal activity: optogenetics which utilize engineered channelrhodopsin and other opsins, and chemogenetics which utilize engineered G protein-coupled receptors (Designer Receptors Exclusively Activated by Designer Drugs (DREADDs)) and other orthologous ligand–receptor pairs. Using directed molecular evolution, two types of DREADDs derived from human muscarinic acetylcholine receptors have been developed: hM3Dq which activates neuronal firing, and hM4Di which inhibits neuronal firing. Importantly, these DREADDs were not activated by the native ligand acetylcholine (ACh), but selectively activated by clozapine N-oxide (CNO), a pharmacologically inert ligand. CNO has been used extensively in rodent models to activate DREADDs, and although CNO is not subject to significant metabolic transformation in mice, a small fraction of CNO is apparently metabolized to clozapine in humans and guinea pigs, lessening the translational potential of DREADDs. To effectively translate the DREADD technology, the next generation of DREADD agonists are needed and a thorough understanding of structure–activity relationships (SARs) of DREADDs is required for developing such ligands. We therefore conducted the first SAR studies of hM3Dq. We explored multiple regions of the scaffold represented by CNO, identified interesting SAR trends, and discovered several compounds that are very potent hM3Dq agonists but do not activate the native human M3 receptor (hM3). We also discovered that the approved drug perlapine is a novel hM3Dq agonist with >10 000-fold selectivity for hM3Dq over hM3. PMID:25587888

  3. Regional climate: Design and analysis of computer experiments?

    NASA Astrophysics Data System (ADS)

    Nychka, D. W.

    2011-12-01

    As attention shifts from broad global summaries of climate change to more specific regional impacts there is a need for data sciences to quantify the uncertainty in regional predictions. This talk will provide an overview on regional climate experiments with an emphasis on the statistical problems for interpreting these large and complex simulations. A regional climate model is a computer code based on physics that simulates the detailed flow of the atmosphere in a particular region from the large scale information of a global climate model. One intent is to compare simulations under current climate to future scenarios to infer the nature of climate change expected at a location. There exists a mature sub-discipline in engineering and statistics on the design and analysis of computer experiments. This talk will sketch how general methods from this area may apply to the interpretation of climate model experiments and to what extent the problems of interpreting climate projections are unique and require new ideas.

  4. Simulation of Active-Region-Scale Flux Emergence

    NASA Astrophysics Data System (ADS)

    Manchester, W.; van der Holst, B.

    2015-12-01

    Shear flows long observed in solar active regions are now understood to be a consequence of the Lorentz force that develops from a complex interaction between magnetic fields and the thermal pressure of the Sun's gravitationally stratified atmosphere. The shearing motions transport magnetic flux and energy from the submerged portion of the field to the corona providing the necessary energy for flares, filament eruptions and CMEs. To further examine this shearing process, we simulate flux emergence on the scale of active regions with a large-scale model of the near surface convection zone constructed on an adaptive spherical grid. This model is designed to simulate flux emerging on the scale of active regions from a depth of 30 Mm. Here, we show results of a twisted flux rope emerging through the hierarchy of granular convection, and examine the flow patterns that arise as the flux approaches the photosphere. We show how these organized flows driven by the Lorentz force cause the coronal field evolve to a highly non-potential configuration capable of driving solar eruptions such as CMEs and flares.

  5. Designing Physical Activities for Metaphorical Communication.

    ERIC Educational Resources Information Center

    Gillis, H. Lee; Edwards, Marianne

    1987-01-01

    Presents to student affairs professionals a process for designing physical activities that can actively and metaphorically communicate a message and that can be implemented as part of staff inservice, retreats, or orientations. Describes rationale for activities, historical overview, and example of burnout prevention metaphor for resident…

  6. Nuclear design of a very-low-activation fusion reactor

    SciTech Connect

    Cheng, E.T.; Hopkins, G.R.

    1983-06-01

    An investigation was conducted to study the nuclear design aspects of using very-low-activation materials, such as SiC, MgO, and aluminum for fusion-reactor first wall, blanket, and shield applications. In addition to the advantage of very-low radioactive inventory, it was found that the very-low-activation fusion reactor can also offer an adequate tritium-breeding ratio and substantial amount of blanket nuclear heating as a conventional-material-structured reactor does. The most-stringent design constraint found in a very-low-activation fusion reactor is the limited space available in the inboard region of a tokamak concept for shielding to protect the superconducting toroidal field coil. A reference design was developed which mitigates the constraint by adopting a removable tungsten shield design that retains the inboard dimensions and gives the same shield performance as the reference STARFIRE tokamak reactor design.

  7. Design of a turbofan powered regional transport aircraft

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The majority of the market for small commercial transport aircraft is dominated by high-efficiency, propeller-driven aircraft of non-U.S. manufacture. During the past year senior student design teams at Purdue developed and then responded to a Request For Proposal (RFP) for a regional transport aircraft. The RFP development identified promising world markets and their needs. The students responded by designing aircraft with ranges of up to 1500 n.m. and passenger loads of 50 to 90. During the design project, special emphasis was placed upon keeping acquisition cost and direct operating costs at a low level while providing passengers with quality comfort levels. Twelve student teams worked for one semester developing their designs. Several of the more successful designs and those that placed a high premium on innovation are described. The depth of detail and analysis in these student efforts are also illustrated.

  8. The Limit of Free Magnetic Energy in Active Regions

    NASA Technical Reports Server (NTRS)

    Moore, Ron; Falconer, David; Sterling, Alphonse

    2012-01-01

    By measuring from active-region magnetograms a proxy of the free energy in the active region fs magnetic field, it has been found previously that (1) there is an abrupt upper limit to the free energy the field can hold that increases with the amount of magnetic field in the active region, the active region fs magnetic flux content, and (2) the free energy is usually near its limit when the field explodes in a CME/flare eruption. That is, explosive active regions are concentrated in a main-sequence path bordering the free-energy ]limit line in (flux content, free-energy proxy) phase space. Here, from measurement of Marshall Space Flight Center vector magnetograms, we find the magnetic condition that underlies the free ]energy limit and the accompanying main sequence of explosive active regions. Using a suitable free ]energy proxy measured from vector magnetograms of 44 active regions, we find that (1) in active regions at and near their free ]energy limit, the ratio of magnetic-shear free energy to the non ]free magnetic energy the potential field would have is approximately 1 in the core field, the field rooted along the neutral line, and (2) this ratio is progressively less in active regions progressively farther below their free ]energy limit. This shows that most active regions in which this core-field energy ratio is much less than 1 cannot be triggered to explode; as this ratio approaches 1, most active regions become capable of exploding; and when this ratio is 1 or greater, most active regions are compelled to explode. From these results we surmise the magnetic condition that determines the free ]energy limit is the ratio of the free magnetic energy to the non-free energy the active region fs field would have were it completely relaxed to its potential ]field configuration, and that this ratio is approximately 1 at the free-energy limit and in the main sequence of explosive active regions.

  9. Physical Activity Design Guidelines for School Architecture

    PubMed Central

    Brittin, Jeri; Sorensen, Dina; Trowbridge, Matthew; Lee, Karen K.; Breithecker, Dieter; Frerichs, Leah; Huang, Terry

    2015-01-01

    Increasing children’s physical activity at school is a national focus in the U.S. to address childhood obesity. While research has demonstrated associations between aspects of school environments and students’ physical activity, the literature currently lacks a synthesis of evidence to serve as a practical, spatially-organized resource for school designers and decision-makers, as well as to point to pertinent research opportunities. This paper describes the development of a new practical tool: Physical Activity Design Guidelines for School Architecture. Its aims are to provide architects and designers, as well as school planners, educators, and public health professionals, with strategies for making K-12 school environments conducive to healthy physical activity, and to engage scientists in transdisciplinary perspectives toward improved knowledge of the school environment’s impact. We used a qualitative review process to develop evidence-based and theory-driven school design guidelines that promote increased physical activity among students. The design guidelines include specific strategies in 10 school design domains. Implementation of the guidelines is expected to enable students to adopt healthier physical activity behaviors. The tool bridges a translational gap between research and environmental design practice, and may contribute to setting new industry and education standards. PMID:26230850

  10. Physical Activity Design Guidelines for School Architecture.

    PubMed

    Brittin, Jeri; Sorensen, Dina; Trowbridge, Matthew; Lee, Karen K; Breithecker, Dieter; Frerichs, Leah; Huang, Terry

    2015-01-01

    Increasing children's physical activity at school is a national focus in the U.S. to address childhood obesity. While research has demonstrated associations between aspects of school environments and students' physical activity, the literature currently lacks a synthesis of evidence to serve as a practical, spatially-organized resource for school designers and decision-makers, as well as to point to pertinent research opportunities. This paper describes the development of a new practical tool: Physical Activity Design Guidelines for School Architecture. Its aims are to provide architects and designers, as well as school planners, educators, and public health professionals, with strategies for making K-12 school environments conducive to healthy physical activity, and to engage scientists in transdisciplinary perspectives toward improved knowledge of the school environment's impact. We used a qualitative review process to develop evidence-based and theory-driven school design guidelines that promote increased physical activity among students. The design guidelines include specific strategies in 10 school design domains. Implementation of the guidelines is expected to enable students to adopt healthier physical activity behaviors. The tool bridges a translational gap between research and environmental design practice, and may contribute to setting new industry and education standards. PMID:26230850

  11. Physical Activity Design Guidelines for School Architecture.

    PubMed

    Brittin, Jeri; Sorensen, Dina; Trowbridge, Matthew; Lee, Karen K; Breithecker, Dieter; Frerichs, Leah; Huang, Terry

    2015-01-01

    Increasing children's physical activity at school is a national focus in the U.S. to address childhood obesity. While research has demonstrated associations between aspects of school environments and students' physical activity, the literature currently lacks a synthesis of evidence to serve as a practical, spatially-organized resource for school designers and decision-makers, as well as to point to pertinent research opportunities. This paper describes the development of a new practical tool: Physical Activity Design Guidelines for School Architecture. Its aims are to provide architects and designers, as well as school planners, educators, and public health professionals, with strategies for making K-12 school environments conducive to healthy physical activity, and to engage scientists in transdisciplinary perspectives toward improved knowledge of the school environment's impact. We used a qualitative review process to develop evidence-based and theory-driven school design guidelines that promote increased physical activity among students. The design guidelines include specific strategies in 10 school design domains. Implementation of the guidelines is expected to enable students to adopt healthier physical activity behaviors. The tool bridges a translational gap between research and environmental design practice, and may contribute to setting new industry and education standards.

  12. Design of small gas cooled fast reactor with two region of natural Uranium fuel fraction

    NASA Astrophysics Data System (ADS)

    Ariani, Menik; Su'ud, Zaki; Waris, Abdul; Khairurrijal, Monado, Fiber; Sekimoto, Hiroshi; Nakayama, Sinsuke

    2012-06-01

    A design study of small Gas Cooled Fast Reactor with two region fuel has been performed. In this study, design GCFR with Helium coolant which can be continuously operated by supplying mixed Natural Uranium without fuel enrichment plant or fuel reprocessing plant. The active reactor cores are divided into two region fuel i.e. 60% fuel fraction of Natural Uranium as inner core and 65% fuel fraction of Natural Uranium as outer core. Each fuel core regions are subdivided into ten parts (region-1 until region-10) with the same volume in the axial direction. The fresh Natural Uranium initially put in region-1, after one cycle of 10 years of burn-up it is shifted to region-2 and the each region-1 filled by fresh Natural Uranium. This concept is basically applied to all regions in both cores area, i.e. shifted the core of ith region into i+1 region after the end of 10 years burn-up cycle. For the next cycles, we will add only Natural Uranium on each region-1. The burn-up calculation is performed using collision probability method PIJ (cell burn-up calculation) in SRAC code which then given eight energy group macroscopic cross section data to be used in two dimensional R-Z geometry multi groups diffusion calculation in CITATION code. This reactor can results power thermal 600 MWth with average power density i.e. 80 watt/cc. After reactor start-up the operation, furthermore reactor only needs Natural Uranium supply for continue operation along 100 years. This calculation result then compared with one region fuel design i.e. 60% and 65% fuel fraction. This core design with two region fuel fraction can be an option for fuel optimization.

  13. DESIGN CONSIDERATION INVOLVING ACTIVE SEDIMENT CAPS

    EPA Science Inventory

    When contaminated sediments pose unacceptable risks to human health and the environment, management activities such as removal, treatment, or isolation of contaminated sediments may be required. Various capping designs are being considered for isolating contaminated sediment are...

  14. DESIGN CONSIDERATION INVOLVING ACTIVE SEDIMENT CAPS (PRESENTATION)

    EPA Science Inventory

    When contaminated sediments pose unacceptable risks to human health and the environment, management activities such as removal, treatment, or isolation of contaminated sediments may be required. Various capping designs are being considered for isolating contaminated sediment are...

  15. Regional differences in muscle activation during hamstrings exercise.

    PubMed

    Schoenfeld, Brad J; Contreras, Bret; Tiryaki-Sonmez, Gul; Wilson, Jacob M; Kolber, Morey J; Peterson, Mark D

    2015-01-01

    It is believed that regional activation within a muscle may lead to greater site-specific muscular adaptations in the activated portion of the muscle. Because the hamstrings are a biarticular muscle, it can be theorized that single-joint exercises where movement originates at the hip vs. the knee will result in differential activation of the muscle complex. The purpose of the present study was to assess electromyographic activity in the proximal and distal aspects of the medial and lateral hamstrings during performance of the stiff-legged deadlift (SLDL), a hip-dominant exercise, and the lying leg curl (LLC), a knee-dominant exercise. Ten young, resistance-trained men were recruited from a university population to participate in the study. Employing a within-subject design, participants performed the SLDL and LLC to muscular failure using a load equating to their 8 repetition maximum for each exercise. The order of performance of exercises was counterbalanced between participants so that approximately half of the subjects performed SLDL first and the other half performed LLC first. Surface electromyography was used to record mean normalized muscle activity of the upper lateral hamstrings, lower lateral hamstrings, upper medial hamstrings, and lower medial hamstrings. Results showed that the LLC elicited significantly greater normalized mean activation of the lower lateral and lower medial hamstrings compared with the SLDL (p ≤ 0.05). These findings support the notion that the hamstrings can be regionally targeted through exercise selection. Further investigations are required to determine whether differences in activation lead to greater muscular adaptations in the muscle complex. PMID:24978835

  16. Statistical Analysis of Acoustic Wave Parameters Near Solar Active Regions

    NASA Astrophysics Data System (ADS)

    Rabello-Soares, M. Cristina; Bogart, Richard S.; Scherrer, Philip H.

    2016-08-01

    In order to quantify the influence of magnetic fields on acoustic mode parameters and flows in and around active regions, we analyze the differences in the parameters in magnetically quiet regions nearby an active region (which we call “nearby regions”), compared with those of quiet regions at the same disk locations for which there are no neighboring active regions. We also compare the mode parameters in active regions with those in comparably located quiet regions. Our analysis is based on ring-diagram analysis of all active regions observed by the Helioseismic and Magnetic Imager (HMI) during almost five years. We find that the frequency at which the mode amplitude changes from attenuation to amplification in the quiet nearby regions is around 4.2 mHz, in contrast to the active regions, for which it is about 5.1 mHz. This amplitude enhacement (the “acoustic halo effect”) is as large as that observed in the active regions, and has a very weak dependence on the wave propagation direction. The mode energy difference in nearby regions also changes from a deficit to an excess at around 4.2 mHz, but averages to zero over all modes. The frequency difference in nearby regions increases with increasing frequency until a point at which the frequency shifts turn over sharply, as in active regions. However, this turnover occurs around 4.9 mHz, which is significantly below the acoustic cutoff frequency. Inverting the horizontal flow parameters in the direction of the neigboring active regions, we find flows that are consistent with a model of the thermal energy flow being blocked directly below the active region.

  17. Active Learning through Toy Design and Development

    ERIC Educational Resources Information Center

    Sirinterlikci, Arif; Zane, Linda; Sirinterlikci, Aleea L.

    2009-01-01

    This article presents an initiative that is based on active learning pedagogy by engaging elementary and middle school students in the toy design and development field. The case study presented in this article is about student learning experiences during their participation in the TOYchallenge National Toy Design Competition. Students followed the…

  18. Prediction of the becalmed region for LP turbine profile design

    SciTech Connect

    Schulte, V.; Hodson, H.P.

    1998-10-01

    Recent attention has focused on the so-called ``becalmed region`` that is observed inside the boundary layers of turbomachinery blading and is associated with the process of wake-induced transition. Significant reductions of profile loss have been shown for high lift LP turbine blades at low Reynolds numbers due to the effects of the becalmed region on the diffusing flow at the rear of the suction surface. In this paper the nature and the significance of the becalmed region are examined using experimental observations and computational studies. It is shown that the becalmed region may be modeled using the unsteady laminar boundary layer equations. Therefore, it is predictable independent of the transition or turbulence models employed. The effect of the becalmed region on the transition process is modeled using a spot-based intermittency transition model. An unsteady differential boundary layer code was used to simulate a deterministic experiment involving an isolated turbulent spot numerically. The predictability of the becalmed region means that the rate of entropy production can be calculated in that region. It is found to be of the order of that in a laminar boundary layer. It is for this reason and because the becalmed region may be encroached upon by pursuing turbulent flows that for attached boundary layers, wake-induced transition cannot significantly reduce the profile loss. However, the becalmed region is less prone to separation than a conventional laminar boundary layer. Therefore, the becalmed region may be exploited in order to prevent boundary layer separation and the increase in loss that this entails. It is shown that it should now be possible to design efficient high lift LP turbine blades.

  19. Eagle RTS: A design of a regional transport

    NASA Technical Reports Server (NTRS)

    Bryer, Paul; Buckles, Jon; Lemke, Paul; Peake, Kirk

    1992-01-01

    The Eagle RTS (Regional Transport System) is a 66-passenger aircraft designed to satisfy the need for accessible and economical regional travel. The first design objective for the Eagle RTS is safety. Safety results primarily from avoidance of the hub airport air traffic, implementation of anti-stall characteristics by tailoring the canard, and proper positioning of the engines for blade shedding. To provide the most economical aircraft, the Eagle RTS will use existing technology to lower production and maintenance costs by decreasing the amount of new training required. In selecting the propulsion system, the effects on the environment were a main consideration. Two advantages of turbo-prop engines are the high fuel efficiency and low noise levels produced by this type of engine. This ensures the aircraft's usage during times of rising fuel costs and growing aircraft noise restrictions. The design of the Eagle RTS is for spoke-to-spoke transportation. It must be capable of landing on shorter runways and have speeds comparable to that of the larger aircraft to make its service beneficial to the airlines. With the use of turbo-prop engines and high lift devices, the Eagle RTS is highly adaptable to regional airports. The design topics discussed include: aerodynamics, stability, structures and materials, propulsion, and cost.

  20. Karyotype Analysis Activity: A Constructivist Learning Design

    ERIC Educational Resources Information Center

    Ahmed, Noveera T.

    2015-01-01

    This classroom activity is based on a constructivist learning design and engages students in physically constructing a karyotype of three mock patients. Students then diagnose the chromosomal aneuploidy based on the karyotype, list the symptoms associated with the disorder, and discuss the implications of the diagnosis. This activity is targeted…

  1. Interaction Region Design and Detector Integration at JLab's MEIC

    SciTech Connect

    Lin, Fanglei; Brindza, Paul D.; Derbenev, Yaroslav S.; Ent, Rolf; Morozov, Vasiliy; Nadel-Turonski, Pawel A.; Zhang, Yuhong; Hyde, Charles E.; Sullivan, Michael

    2013-12-01

    The Electron Ion Collider (EIC) will be a next-generation facility for the study of the strong interaction (QCD). JLab's MEIC is designed for high luminosities of up to 10^34 cm^-2 s^-1. This is achieved in part due to an aggressively small beta-star, which imposes stringent requirements on the collider rings' dynamical properties. Additionally, one of the unique features of MEIC is a full-acceptance detector with a dedicated, small-angle, high-resolution detection system, capable of covering a wide range of momenta (and charge-to-mass ratios) with respect to the original ion beam to enable access to new physics. The detector design relies on a number of features, such as a 50 mrad beam crossing angle, large-aperture ion and electron final focusing quads and spectrometer dipoles as well as a large machine-element-free detection space downstream of the final focusing quads. We present an interaction region design developed with close integration of the detector and beam dynamical aspects. The dynamical aspect of the design rests on a symmetry-based concept for compensation of non-linear effects. The optics and geometry have been optimized to accommodate the detection requirements and to ensure the interaction region's modularity for easiness of integration into the collider ring lattices. As a result, the design offers an excellent detector performance combined with the necessary non-linear dynamical properties.

  2. Tracked Active Region Patches for MDI and HMI

    NASA Astrophysics Data System (ADS)

    Turmon, Michael; Hoeksema, J. Todd; Bobra, Monica

    2014-06-01

    We describe tracked active-region patch data products that have been developed for HMI (HMI Active Region Patches, or HARPs) and for MDI (MDI Tracked Active Region Patches, or MDI TARPs). Both data products consist of tracked magnetic features on the scale of solar active regions. The now-released HARP data product covers 2010-present (>2000 regions to date). Like the HARPs, the MDI TARP data set is a catalog of active regions (ARs), indexed by a region ID number, analogous to a NOAA AR number, and time. The TARPs contain 6170 regions spanning 72000 images taken over 1996-2010, and will be availablein the MDI resident archive (RA).MDI TARPs are computed based on the 96-minute synoptic magnetograms and intensitygrams. As with the related HARP data product, the approximate threshold for significance is 100G. Use of both image types together allows faculae and sunspots to be separated out as sub-classes of activity, in addition to identifying the overall active region that they are in. After being identified in single images, the magnetically-active patches are grouped and tracked from image to image. Merges among growing active regions, as well as faint active regions hovering at the threshold of detection, are handled automatically. Regions are tracked from their inception until they decay within view, or transit off the visible disk. For each active region and for each time, a bitmap image is stored containing the precise outline of the active region. Also, metadata such as areas and integrated fluxes are stored for each AR and for each time. Because there is a cross-calibration between the HMI and MDI magnetograms (Liu et al. 2012), it is straightforward to use the same classification and tracking rules for the HMI HARPs and the MDI TARPs. We show results demonstrating region correspondence, region boundary agreement, and agreement of flux metadata using the approximately 140 regions in the May 2010-October 2010 time period. We envision several uses for these data

  3. CLC Regional Activity Report (1999-2000).

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific and Cultural Organization, Bangkok (Thailand). Principal Regional Office for Asia and the Pacific.

    Community learning centers (CLCs) are local educational institutions outside the formal education system that are usually established and managed by local people to provide various learning opportunities designed to empower individuals and promote community development for all community members regardless of age or socioeconomic group. CLCs…

  4. GLOBAL DYNAMICS OF SUBSURFACE SOLAR ACTIVE REGIONS

    SciTech Connect

    Jouve, L.; Brun, A. S.

    2013-01-01

    We present three-dimensional numerical simulations of a magnetic loop evolving in either a convectively stable or unstable rotating shell. The magnetic loop is introduced into the shell in such a way that it is buoyant only in a certain portion in longitude, thus creating an {Omega}-loop. Due to the action of magnetic buoyancy, the loop rises and develops asymmetries between its leading and following legs, creating emerging bipolar regions whose characteristics are similar to those of observed spots at the solar surface. In particular, we self-consistently reproduce the creation of tongues around the spot polarities, which can be strongly affected by convection. We further emphasize the presence of ring-shaped magnetic structures around our simulated emerging regions, which we call 'magnetic necklace' and which were seen in a number of observations without being reported as of today. We show that those necklaces are markers of vorticity generation at the periphery and below the rising magnetic loop. We also find that the asymmetry between the two legs of the loop is crucially dependent on the initial magnetic field strength. The tilt angle of the emerging regions is also studied in the stable and unstable cases and seems to be affected both by the convective motions and the presence of a differential rotation in the convective cases.

  5. OBSERVING CORONAL NANOFLARES IN ACTIVE REGION MOSS

    SciTech Connect

    Testa, Paola; DeLuca, Ed; Golub, Leon; Korreck, Kelly; Weber, Mark; De Pontieu, Bart; Martinez-Sykora, Juan; Title, Alan; Hansteen, Viggo; Cirtain, Jonathan; Winebarger, Amy; Kobayashi, Ken; Kuzin, Sergey; Walsh, Robert; DeForest, Craig

    2013-06-10

    The High-resolution Coronal Imager (Hi-C) has provided Fe XII 193A images of the upper transition region moss at an unprecedented spatial ({approx}0.''3-0.''4) and temporal (5.5 s) resolution. The Hi-C observations show in some moss regions variability on timescales down to {approx}15 s, significantly shorter than the minute-scale variability typically found in previous observations of moss, therefore challenging the conclusion of moss being heated in a mostly steady manner. These rapid variability moss regions are located at the footpoints of bright hot coronal loops observed by the Solar Dynamics Observatory/Atmospheric Imaging Assembly in the 94 A channel, and by the Hinode/X-Ray Telescope. The configuration of these loops is highly dynamic, and suggestive of slipping reconnection. We interpret these events as signatures of heating events associated with reconnection occurring in the overlying hot coronal loops, i.e., coronal nanoflares. We estimate the order of magnitude of the energy in these events to be of at least a few 10{sup 23} erg, also supporting the nanoflare scenario. These Hi-C observations suggest that future observations at comparable high spatial and temporal resolution, with more extensive temperature coverage, are required to determine the exact characteristics of the heating mechanism(s).

  6. Subsurface helicity of active regions 12192 and 10486

    NASA Astrophysics Data System (ADS)

    Komm, Rudolf; Tripathy, Sushant; Howe, Rachel; Hill, Frank

    2015-04-01

    The active region 10486 that produced the Halloween flares in 2003 initiated our interest in the kinetic helicity of subsurface flows associated with active regions. This lead to the realization that the helicity of subsurface flows is related to the flare activity of active regions. Eleven years later, a similarly enormous active region (12192) appeared on the solar surface. We plan to study the kinetic helicity of the subsurface flows associated with region 12192 and compare it to that of region 10486. For 10486, we have analyzed Dopplergrams obtained with the Michelson Doppler Imager (MDI) onboard the Solar and Heliospheric Observatory (SOHO) and the Global Oscillation Network Group (GONG) with a dense-pack ring-diagram analysis. For 12192, we have analyzed Dopplergrams from GONG and the Helioseismic and Magnetic Imager (HMI) onboard the Solar Dynamics Observatory (SDO). We will present the latest results.

  7. A Fractal Dimension Survey of Active Region Complexity

    NASA Technical Reports Server (NTRS)

    McAteer, R. T. James; Gallagher, Peter; Ireland, Jack

    2005-01-01

    A new approach to quantifying the magnetic complexity of active regions using a fractal dimension measure is presented. This fully-automated approach uses full disc MDI magnetograms of active regions from a large data set (2742 days of the SoHO mission; 9342 active regions) to compare the calculated fractal dimension to both Mount Wilson classification and flare rate. The main Mount Wilson classes exhibit no distinct fractal dimension distribution, suggesting a self-similar nature of all active regions. Solar flare productivity exhibits an increase in both the frequency and GOES X-ray magnitude of flares from regions with higher fractal dimensions. Specifically a lower threshold fractal dimension of 1.2 and 1.25 exists as a necessary, but not sufficient, requirement for an active region to produce M- and X-class flares respectively .

  8. Fostering Teachers' Design Expertise in Teacher Design Teams: Conducive Design and Support Activities

    ERIC Educational Resources Information Center

    Huizinga, Tjark; Handelzalts, Adam; Nieveen, Nienke; Voogt, Joke

    2015-01-01

    Supporting Teacher Design Teams (TDTs) during local curriculum development efforts is essential. To be able to provide high-quality support, insights are needed about how TDTs carry out design activities and how support is valued by the members of TDTs and how it affects their design expertise. In this study, the design and support processes of…

  9. Participatory Design Activities and Agile Software Development

    NASA Astrophysics Data System (ADS)

    Kautz, Karlheinz

    This paper contributes to the studies of design activities in information systems development. It provides a case study of a large agile development project and focusses on how customers and users participated in agile development and design activities in practice. The investigated project utilized the agile method eXtreme Programming. Planning games, user stories and story cards, working software, and acceptance tests structured the customer and user involvement. We found genuine customer and user involvement in the design activities in the form of both direct and indirect participation in the agile development project. The involved customer representatives played informative, consultative, and participative roles in the project. This led to their functional empowerment— the users were enabled to carry out their work to their own satisfaction and in an effective, efficient, and economical manner.

  10. CHP REGIONAL APPLICATION CENTERS: ACTIVITIES AND SELECTED RESULTS

    SciTech Connect

    Schweitzer, Martin

    2010-08-01

    Between 2001 and 2005, the U.S. Department of Energy (DOE) created a set of eight Regional Application Centers (RACs) to facilitate the development and deployment of Combined Heat and Power (CHP) technologies. By utilizing the thermal energy that is normally wasted when electricity is produced at central generating stations, Combined Heat and Power installations can save substantial amounts of energy compared to more traditional technologies. In addition, the location of CHP facilities at or near the point of consumption greatly reduces or eliminates electric transmission and distribution losses. The regional nature of the RACs allows each one to design and provide services that are most relevant to the specific economic and market conditions in its particular geographic area. Between them, the eight RACs provide services to all 50 states and the District of Columbia. Through the end of the federal 2009 fiscal year (FY 2009), the primary focus of the RACs was on providing CHP-related information to targeted markets, encouraging the creation and adoption of public policies and incentives favorable to CHP, and providing CHP users and prospective users with technical assistance and support on specific projects. Beginning with the 2010 fiscal year, the focus of the regional centers broadened to include district energy and waste heat recovery and these entities became formally known as Clean Energy Application Centers, as required by the Energy Independence and Security Act (EISA) of 2007. In 2007, ORNL led a cooperative effort to establish metrics to quantify the RACs accomplishments. That effort began with the development of a detailed logic model describing RAC operations and outcomes, which provided a basis for identifying important activities and accomplishments to track. A data collection spreadsheet soliciting information on those activities for FY 2008 and all previous years of RAC operations was developed and sent to the RACs in the summer of 2008. This

  11. The birth and evolution of solar active regions

    NASA Astrophysics Data System (ADS)

    Gaizauskas, V.

    1993-09-01

    The growth of solar active regions is a well-observed surface phenomenon with its origins concealed in the solar interior. We review the salient facts about the emergence of active regions and the consequences of their growth on the solar atmosphere. The most powerful flares, the ones which display a range of phenomena that still pose serious challenges for high-energy astrophysics, are associated with regions of high magnetic complexity. How does that degree of complexity arise when the vast majority of active regions are simple bipolar entities? In order to gain some insight into that problem, we compare the emergence of magnetic flux in ordinary regions with an instance when magnetic complexity is apparent from the very first appearance of a new region - clearly a subsurface prefabrication of complexity - and with others wherein a new region interacts with a pre-existing one to create the complexity in plain view.

  12. IFLA General Conference, 1985. Division on Regional Activities. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    Papers on regional library activities which were presented at the 1985 International Federation of Library Associations (IFLA) conference include: (1) "Importance of Information Resources in National Development with Particular Reference to the Asian Scene" (Yogendra P. Dubey, India); (2) "Report of the Activities of the Regional Section for Asia…

  13. X-33 Base Region Thermal Protection System Design Study

    NASA Technical Reports Server (NTRS)

    Lycans, Randal W.

    1998-01-01

    The X-33 is an advanced technology demonstrator for validating critical technologies and systems required for an operational Single-Stage-to-Orbit (SSTO) Reusuable Launch Vehicle (RLV). Currently under development by a unique contractor/government team led by Lockheed- Martin Skunk Works (LMSW), and managed by Marshall Space Flight Center (MSFC), the X-33 will be the prototype of the first new launch system developed by the United States since the advent of the space shuttle. This paper documents a design trade study of the X-33 base region thermal protection system (TPS). Two candidate designs were evaluated for thermal performance and weight. The first candidate was a fully reusable metallic TPS using Inconel honeycomb panels insulated with high temperature fibrous insulation, while the second was an ablator/insulator sprayed on the metallic skin of the vehicle. The TPS configurations and insulation thickness requirements were determined for the predicted main engine plume heating environments and base region entry aerothermal environments. In addition to thermal analysis of the design concepts, sensitivity studies were performed to investigate the effect of variations in key parameters of the base TPS analysis.

  14. Software Displays Data on Active Regions of the Sun

    NASA Technical Reports Server (NTRS)

    Golightly, Mike; Weyland, Mark; Raben, Vern

    2011-01-01

    The Solar Active Region Display System is a computer program that generates, in near real time, a graphical display of parameters indicative of the spatial and temporal variations of activity on the Sun. These parameters include histories and distributions of solar flares, active region growth, coronal mass ejections, size, and magnetic configuration. By presenting solar-activity data in graphical form, this program accelerates, facilitates, and partly automates what had previously been a time-consuming mental process of interpretation of solar-activity data presented in tabular and textual formats. Intended for original use in predicting space weather in order to minimize the exposure of astronauts to ionizing radiation, the program might also be useful on Earth for predicting solar-wind-induced ionospheric effects, electric currents, and potentials that could affect radio-communication systems, navigation systems, pipelines, and long electric-power lines. Raw data for the display are obtained automatically from the Space Environment Center (SEC) of the National Oceanic and Atmospheric Administration (NOAA). Other data must be obtained from the NOAA SEC by verbal communication and entered manually. The Solar Active Region Display System automatically accounts for the latitude dependence of the rate of rotation of the Sun, by use of a mathematical model that is corrected with NOAA SEC active-region position data once every 24 hours. The display includes the date, time, and an image of the Sun in H light overlaid with latitude and longitude coordinate lines, dots that mark locations of active regions identified by NOAA, identifying numbers assigned by NOAA to such regions, and solar-region visual summary (SRVS) indicators associated with some of the active regions. Each SRVS indicator is a small pie chart containing five equal sectors, each of which is color-coded to provide a semiquantitative indication of the degree of hazard posed by one aspect of the activity at

  15. INTERACTION REGION DESIGN FOR THE ELECTRON-ION COLLIDER ERHIC.

    SciTech Connect

    MONTAG, C.; PARKER, B.; TEPIKIAN, S.; ET AL.

    2005-05-16

    To facilitate the study of collisions between 10 GeV polarized electrons and 100 GeV/u heavy ions or 250 GeV polarized protons at luminosities in the 10{sup 33} cm{sup -2} sec{sup -1} range (e-p case), adding a 10 GeV electron storage ring to the existing RHIC complex has been proposed. The interaction region of this electron-ion collider eRHIC has to provide the required low-beta focusing, while simultaneously accommodating the synchrotron radiation fan generated by beam separation close to the interaction point, which is particularly challenging. The latest design status of the eRHIC interaction region will be presented.

  16. Magnet design of the ENC@FAIR interaction region

    SciTech Connect

    Schnizer, P.; Montag, C.; Aulenbacher, K.; Jankowiak, A.; Ludwig-Mertin, U.

    2010-05-23

    The Electron Nucleon Collider, proposed as an extension to the High Energy Storage Ring (HESR), is currently investigated and a first layout of the Interaction Region (IR) proposed. The limited size of the machine, the low beam energy and the Lorentz force vector pointing in the same direction for both beams make the IR design demanding. In this paper we present the parameters of the IR magnets, show the boundary conditions given by the beam dynamics and the experiments. We present first 2D designs for the electron and proton triplet magnets along with the separating dipole next to the collision point. Different methods to shield the beam in the spectrometer dipoles are investigated and presented.

  17. 3D MHD Models of Active Region Loops

    NASA Technical Reports Server (NTRS)

    Ofman, Leon

    2004-01-01

    Present imaging and spectroscopic observations of active region loops allow to determine many physical parameters of the coronal loops, such as the density, temperature, velocity of flows in loops, and the magnetic field. However, due to projection effects many of these parameters remain ambiguous. Three dimensional imaging in EUV by the STEREO spacecraft will help to resolve the projection ambiguities, and the observations could be used to setup 3D MHD models of active region loops to study the dynamics and stability of active regions. Here the results of 3D MHD models of active region loops are presented, and the progress towards more realistic 3D MHD models of active regions. In particular the effects of impulsive events on the excitation of active region loop oscillations, and the generation, propagations and reflection of EIT waves are shown. It is shown how 3D MHD models together with 3D EUV observations can be used as a diagnostic tool for active region loop physical parameters, and to advance the science of the sources of solar coronal activity.

  18. Active array design for FAME: Freeform Active Mirror Experiment

    NASA Astrophysics Data System (ADS)

    Jaskó, Attila; Aitink-Kroes, Gabby; Agócs, Tibor; Venema, Lars; Hugot, Emmanuel; Schnetler, Hermine; Bányai, Evelin

    2014-07-01

    In this paper a status report is given on the development of the FAME (Freeform Active Mirror Experiment) active array. Further information regarding this project can be found in the paper by Venema et al. (this conference). Freeform optics provide the opportunity to drastically reduce the complexity of the future optical instruments. In order to produce these non-axisymmetric freeform optics with up to 1 mm deviation from the best fit sphere, it is necessary to come up with new design and manufacturing methods. The way we would like to create novel freeform optics is by fine tuning a preformed high surface-quality thin mirror using an array which is actively controlled by actuators. In the following we introduce the tools deployed to create and assess the individual designs. The result is an active array having optimal number and lay-out of actuators.

  19. Design of nutrient removal activated sludge systems.

    PubMed

    Manga, J; Ferrer, J; Seco, A; Garcia-Usach, F

    2003-01-01

    A mechanistic mathematical model for nutrient and organic matter removal was used to describe the behavior of a nitrification denitrification enhanced biological phosphorus removal (NDEBPR) system. This model was implemented in a user-friendly software DESASS (design and simulation of activated sludge systems). A 484-L pilot plant was operated to verify the model results. The pilot plant was operated for three years over three different sludge ages. The validity of the model was confirmed with data from the pilot plant. Also, the utility of DESASS as a valuable tool for designing NDEBPR systems was confirmed.

  20. Design of nutrient removal activated sludge systems.

    PubMed

    Manga, J; Ferrer, J; Seco, A; Garcia-Usach, F

    2003-01-01

    A mechanistic mathematical model for nutrient and organic matter removal was used to describe the behavior of a nitrification denitrification enhanced biological phosphorus removal (NDEBPR) system. This model was implemented in a user-friendly software DESASS (design and simulation of activated sludge systems). A 484-L pilot plant was operated to verify the model results. The pilot plant was operated for three years over three different sludge ages. The validity of the model was confirmed with data from the pilot plant. Also, the utility of DESASS as a valuable tool for designing NDEBPR systems was confirmed. PMID:12906279

  1. Regional Observation of Seismic Activity in Baekdu Mountain

    NASA Astrophysics Data System (ADS)

    Kim, Geunyoung; Che, Il-Young; Shin, Jin-Soo; Chi, Heon-Cheol

    2015-04-01

    Seismic unrest in Baekdu Mountain area between North Korea and Northeast China region has called attention to geological research community in Northeast Asia due to her historical and cultural importance. Seismic bulletin shows level of seismic activity in the area is higher than that of Jilin Province of Northeast China. Local volcanic observation shows a symptom of magmatic unrest in period between 2002 and 2006. Regional seismic data have been used to analyze seismic activity of the area. The seismic activity could be differentiated from other seismic phenomena in the region by the analysis.

  2. Local encoding of computationally designed enzyme activity

    PubMed Central

    Allert, Malin; Dwyer, Mary A.; Hellinga, Homme W.

    2007-01-01

    One aim of computational protein design is to introduce novel enzyme activity into proteins of known structure by predicting mutations that stabilize transition states. Previously we have shown that it is possible to introduce triose phosphate isomerase activity into the ribose-binding protein of Escherichia coli by constructing 17 mutations in the first two layers of residues that surround the wild-type ligand-binding site. Here we report that these mutations can be “transplanted” into a homologous ribose-binding protein, isolated from the hyperthermophilic bacterium Thermoanaerobacter tengcongensis, with retention of catalytic activity, substrate affinity, and reaction pH dependence. The observed 105–106-fold rate enhancement corresponds to 70% of the maximally known transition-state binding energy. The wild-type sequences in these two homologues are almost perfectly conserved in the vicinity of their ribose-binding sites, but diverge significantly at increasing distance from these sites. The results demonstrate that the computationally designed mutations are sufficient to encode the observed enzyme activity, that all the observed activity is locally encoded within the layer of residues directly in contact with the substrate, and that in this case at least 70% of transition state stabilization energy can be achieved using straightforward considerations of stereochemical complementarity between enzyme and reactants. PMID:17196220

  3. Prediction of Active-Region CME Productivity from Magnetograms

    NASA Technical Reports Server (NTRS)

    Falconer, D. A.; Moore, R. L.; Gary, G. A.

    2004-01-01

    We report results of an expanded evaluation of whole-active-region magnetic measures as predictors of active-region coronal mass ejection (CME) productivity. Previously, in a sample of 17 vector magnetograms of 12 bipolar active regions observed by the Marshall Space Flight Center (MSFC) vector magnetograph, from each magnetogram we extracted a measure of the size of the active region (the active region s total magnetic flux a) and four measures of the nonpotentiality of the active region: the strong-shear length L(sub SS), the strong-gradient length L(sub SG), the net vertical electric current I(sub N), and the net-current magnetic twist parameter alpha (sub IN). This sample size allowed us to show that each of the four nonpotentiality measures was statistically significantly correlated with active-region CME productivity in time windows of a few days centered on the day of the magnetogram. We have now added a fifth measure of active-region nonpotentiality (the best-constant-alpha magnetic twist parameter (alpha sub BC)), and have expanded the sample to 36 MSFC vector magnetograms of 31 bipolar active regions. This larger sample allows us to demonstrate statistically significant correlations of each of the five nonpotentiality measures with future CME productivity, in time windows of a few days starting from the day of the magnetogram. The two magnetic twist parameters (alpha (sub 1N) and alpha (sub BC)) are normalized measures of an active region s nonpotentially in that they do not depend directly on the size of the active region, while the other three nonpotentiality measures (L(sub SS), L(sub SG), and I(sub N)) are non-normalized measures in that they do depend directly on active-region size. We find (1) Each of the five nonpotentiality measures is statistically significantly correlated (correlation confidence level greater than 95%) with future CME productivity and has a CME prediction success rate of approximately 80%. (2) None of the nonpotentiality

  4. Active Ageing Level of Older Persons: Regional Comparison in Thailand.

    PubMed

    Haque, Md Nuruzzaman

    2016-01-01

    Active ageing level and its discrepancy in different regions (Bangkok, Central, North, Northeast, and South) of Thailand have been examined for prioritizing the policy agenda to be implemented. Attempt has been made to test preliminary active ageing models for Thai older persons and hence active ageing index (AAI, ranges from 0 to 1) has been estimated. Using nationally representative data and confirmatory factor analysis approach, this study justified active ageing models for female and male older persons in Thailand. Results revealed that active ageing level of Thai older persons is not high (mean AAIs for female and male older persons are 0.64 and 0.61, resp., and those are significantly different (p < 0.001)). Mean AAI in Central region is lower than North, Northeast, and South regions but there is no significant difference in the latter three regions of Thailand. Special emphasis should be given to Central region and policy should be undertaken for increasing active ageing level. Implementation of an Integrated Active Ageing Package (IAAP), containing policies for older persons to improve their health and economic security, to promote participation in social groups and longer working lives, and to arrange learning programs, would be helpful for increasing older persons' active ageing level in Thailand. PMID:27375903

  5. Active Ageing Level of Older Persons: Regional Comparison in Thailand.

    PubMed

    Haque, Md Nuruzzaman

    2016-01-01

    Active ageing level and its discrepancy in different regions (Bangkok, Central, North, Northeast, and South) of Thailand have been examined for prioritizing the policy agenda to be implemented. Attempt has been made to test preliminary active ageing models for Thai older persons and hence active ageing index (AAI, ranges from 0 to 1) has been estimated. Using nationally representative data and confirmatory factor analysis approach, this study justified active ageing models for female and male older persons in Thailand. Results revealed that active ageing level of Thai older persons is not high (mean AAIs for female and male older persons are 0.64 and 0.61, resp., and those are significantly different (p < 0.001)). Mean AAI in Central region is lower than North, Northeast, and South regions but there is no significant difference in the latter three regions of Thailand. Special emphasis should be given to Central region and policy should be undertaken for increasing active ageing level. Implementation of an Integrated Active Ageing Package (IAAP), containing policies for older persons to improve their health and economic security, to promote participation in social groups and longer working lives, and to arrange learning programs, would be helpful for increasing older persons' active ageing level in Thailand.

  6. DISTRIBUTION OF ELECTRIC CURRENTS IN SOLAR ACTIVE REGIONS

    SciTech Connect

    Török, T.; Titov, V. S.; Mikić, Z.; Leake, J. E.; Archontis, V.; Linton, M. G.; Dalmasse, K.; Aulanier, G.; Kliem, B.

    2014-02-10

    There has been a long-standing debate on the question of whether or not electric currents in solar active regions are neutralized. That is, whether or not the main (or direct) coronal currents connecting the active region polarities are surrounded by shielding (or return) currents of equal total value and opposite direction. Both theory and observations are not yet fully conclusive regarding this question, and numerical simulations have, surprisingly, barely been used to address it. Here we quantify the evolution of electric currents during the formation of a bipolar active region by considering a three-dimensional magnetohydrodynamic simulation of the emergence of a sub-photospheric, current-neutralized magnetic flux rope into the solar atmosphere. We find that a strong deviation from current neutralization develops simultaneously with the onset of significant flux emergence into the corona, accompanied by the development of substantial magnetic shear along the active region's polarity inversion line. After the region has formed and flux emergence has ceased, the strong magnetic fields in the region's center are connected solely by direct currents, and the total direct current is several times larger than the total return current. These results suggest that active regions, the main sources of coronal mass ejections and flares, are born with substantial net currents, in agreement with recent observations. Furthermore, they support eruption models that employ pre-eruption magnetic fields containing such currents.

  7. Solar Irradiance Variations on Active Region Time Scales

    NASA Technical Reports Server (NTRS)

    Labonte, B. J. (Editor); Chapman, G. A. (Editor); Hudson, H. S. (Editor); Willson, R. C. (Editor)

    1984-01-01

    The variations of the total solar irradiance is an important tool for studying the Sun, thanks to the development of very precise sensors such as the ACRIM instrument on board the Solar Maximum Mission. The largest variations of the total irradiance occur on time scales of a few days are caused by solar active regions, especially sunspots. Efforts were made to describe the active region effects on total and spectral irradiance.

  8. Photospheric Magnetic Diffusion by Measuring Moments of Active Regions

    NASA Astrophysics Data System (ADS)

    Engell, Alexander; Longcope, D.

    2013-07-01

    Photospheric magnetic surface diffusion is an important constraint for the solar dynamo. The HMI Active Region Patches (HARPs) program automatically identify all magnetic regions above a certain flux. In our study we measure the moments of ARs that are no longer actively emerging and can thereby give us good statistical constraints on photospheric diffusion. We also present the diffusion properties as a function of latitude, flux density, and single polarity (leading or following) within each HARP.

  9. Radio Coronal Magnetography of a Large Active Region

    NASA Astrophysics Data System (ADS)

    Bastian, Timothy S.; Gary, Dale E.; White, Stephen; Fleishman, Gregory; Chen, Bin

    2015-04-01

    Quantitative knowledge of coronal magnetic fields is fundamental to understanding energetic phenomena such as solar flares. Flares occur in solar active regions where strong, non-potential magnetic fields provide free energy. While constraints on the coronal magnetic field topology are readily available through high resolution SXR and EUV imaging of solar active regions, useful quantitative measurements of coronal magnetic fields have thus far been elusive. Recent progress has been made at infrared (IR) wavelengths in exploiting both the Zeeman and Hanle effects to infer the line-of-sight magnetic field strength or the orientation of the magnetic field vector in the plane of the sky above the solar limb. However, no measurements of coronal magnetic fields against the solar disk are possible using IR observations. Radio observations of gyroresonance emission from active regions offer the means of measuring coronal magnetic fields above the limb and on the solar disk. In particular, for plasma plasma conditions in the solar corona, active regions typically become optically thick to emission over a range of radio frequencies through gyroresonance absorption at a low harmonic of the electron gyrofrequency. The specific range of resonant frequencies depends on the range of coronal magnetic field strengths present in the active region.The Karl G. Jansky Very Large Array was used in November 2014 to image NOAA/USAF active region AR12209 over a continuous frequency range of 1-8 GHz, corresponding to a wavelength range of 3.75-30 cm. This frequency range is sensitive to coronal magnetic field strengths ranging from ~120-1400G. The active region was observed on four different dates - November 18, 20, 22, and 24 - during which the active region longitude ranged from -15 to +70 degrees, providing a wide range of aspect angles. In this paper we provide a preliminary description of the coronal magnetic field measurements derived from the radio observations.

  10. Eagle RTS: A design for a regional transport aircraft

    NASA Technical Reports Server (NTRS)

    Bryer, Paul; Buckles, Jon; Lemke, Paul; Peake, Kirk

    1992-01-01

    This university design project concerns the Eagle RTS (Regional Transport System), a 66 passenger, twin turboprop aircraft with a range of 836 nautical miles. It will operate with a crew of two pilots and two flight attendents. This aircraft will employ the use of aluminum alloys and composite materials to reduce the aircraft weight and increase aerodynamic efficiency. The Eagle RTS will use narrow body aerodynamics with a canard configuration to improve performance. Leading edge technology will be used in the cockpit to improve flight handling and safety. The Eagle RTS propulsion system will consist of two turboprop engines with a total thrust of approximately 6300 pounds, 3150 pounds thrust per engine, for the cruise configuration. The engines will be mounted on the aft section of the aircraft to increase passenger safety in the event of a propeller failure. Aft mounted engines will also increase the overall efficiency of the aircraft by reducing the aircraft's drag. The Eagle RTS is projected to have a takeoff distance of approximately 4700 feet and a landing distance of 6100 feet. These distances will allow the Eagle RTS to land at the relatively short runways of regional airports.

  11. Interface Region Imaging Spectrograph (IRIS) entrance aperture design

    NASA Astrophysics Data System (ADS)

    Cheimets, P.; Park, S.; Bergner, H.; Chou, C.; Gates, R.; Honsa, M.; Podgorski, W.; Yanari, C.

    2014-07-01

    The Interface Region Imaging Spectrograph (IRIS) is a complementary follow-on to Solar Dynamics Observatory Atmospheric Imaging Assembly (SDO-AIA) and funded as a member of the NASA SMEX program. This paper presents the thermal design of the IRIS telescope front end, with a focus on the IRIS door and entrance aperture assembly. The challenge of the IRIS entrance aperture, including the door design, was to manage the solar flux, both before and after the door was opened. This is especially a problem with instruments that are permanently pointed directly at the sun. Though there is an array of effective flux-rejecting coatings, they are expensive, hard to apply, harder to measure, delicate, prone to unpredictable performance decay with exposure, and very often a source of contamination. This paper presents a thermal control and protection method based on robust, inexpensive coatings and materials, combined to produce high thermal and structural isolation. The end result is a first line of thermal protection whose performance is easy to predict and well isolated from the instrument it is protecting.

  12. Earth resources-regional transfer activity contracts review

    NASA Technical Reports Server (NTRS)

    Bensko, J., Jr.; Daniels, J. L.; Downs, S. W., Jr.; Jones, N. L.; Morton, R. R.; Paludan, C. T.

    1977-01-01

    A regional transfer activity contracts review held by the Earth Resources Office was summarized. Contracts in the earth resources field primarily directed toward applications of satellite data and technology in solution of state and regional problems were reviewed. A summary of the progress of each contract was given in order to share experiences of researchers across a seven state region. The region included Missouri, Kentucky, Tennessee, Mississippi, Alabama, Georgia, and North Carolina. Research in several earth science disciplines included forestry, limnology, water resources, land use, geology, and mathematical modeling. The use of computers for establishment of information retrieval systems was also emphasized.

  13. Tracking Active Region NOAA 12192 in Multiple Carrington Rotations

    NASA Astrophysics Data System (ADS)

    Jain, Kiran; Tripathy, Sushant C.; Hill, Frank

    2015-04-01

    Active region NOAA 12192 appeared on the visible solar disk on October 18, 2014 and grew rapidly into the largest such region since 1990. During its entire transit across the Earth facing side of the Sun, it produced a significant number of X- and M-class flares. The combination of front-side and helioseismic far-side images clearly indicated that it lived through several Carrington rotations. In this paper, using Dopplergrams from GONG and HMI, we present a study on mode parameters, viz. oscillation frequencies, amplitude, and sub-surface flows and investigate how these vary with the evolution of active region in multiple rotations. We also present a detailed comparison between NOAA 10486 (the biggest active region in cycle 23) and NOAA 12192, and discuss the similarities/differences between them.

  14. Active Tectonics And Modern Geodynamics Of Sub-Yerevan Region

    NASA Astrophysics Data System (ADS)

    Avanesyan, M.

    2004-05-01

    The given work is dedicated to active tectonics and modern geodynamics of Sub-Yerevan region. This region is interesting as a one of regions with maximal seismic activity in Armenia. The high level of seismic risk of this region is conditioned by high level of seismic hazard, high density of the population, as well as presence of objects of special importance and industrial capacities. The modern structure of Sub-Yerevan region and the adjacent area, as well as the Caucasus entirely, has mosaic-block appearance, typical for collision zone of Arabian and Eurasian plates. Distinctively oriented active faults of various ranges and morphological types are distinguished. These faults, in their turn, form various-scale active blocks of the Earth's crust and their movement defines seismic activity of the region. The researches show, that all strong earthquakes in the region were caused by movements by newest and activated ancient faults. In order to reveal the character of Earth's crust active blocks movement, separation of high gradients of horizontal and vertical movements and definition of stress fields highest concentration regions by GPS observations, high-accuracy leveling and study of earthquake focal mechanisms a new seismotectonic model is developed, which represents a combination of tectonic structure, seismic data, newest and modern movements. On the basis of comparison and analysis of these data zones with potential maximal seismic hazard are separated. The zone of joint of Azat-Sevan active and Yerevan abysmal faults is the most active on the territory of Sub-Yerevan region. The directions relatively the Earth's crust movement in the zones of horizontal and vertical movement gradients lead to conclusion, that Aragats-Tsakhkunian and Gegam active blocks undergo clockwise rotation. This means, that additional concentration of stress must be observed in block corners, that is confirmed by location of strong earthquakes sources. Thus, on the North 1988 Spitak (M

  15. Universities and Economic Development Activities: A UK Regional Comparison

    ERIC Educational Resources Information Center

    Decter, Moira; Cave, Frank; Rose, Mary; Peers, Gill; Fogg, Helen; Smith, Susan M.

    2011-01-01

    A number of UK universities prioritize economic development or regeneration activities and for some of these universities such activities are the main focus of their knowledge transfer work. This study compares two regions of the UK--the North West and the South East of England--which have very different levels of economic performance.…

  16. Designing an Active Target Test Projection Chamber

    NASA Astrophysics Data System (ADS)

    Koci, James; Tan Ahn Collaboration, Dr.; Nicolas Dixneuf Collaboration

    2015-10-01

    The development of instrumentation in nuclear physics is crucial for advancing our ability to measure the properties of exotic nuclei. One limitation of the use of exotic nuclei in experiment is their very low production intensities. Recently, detectors, called active-target dectectors, have been developed to address this issue. Active-target detectors use a gas medium to image charged-particle tracks that are emitted in nuclear reactions. Last semester, I designed a vacuum chamber to be used in developing Micro-Pattern Gas detectors that will upgrade the capabilities of an active-target detector called the Prototype AT-TPC. With the exterior of the chamber complete, I have now been using an electric field modeling program, Garfield, developed by CERN to design a field cage to be placed within the vacuum chamber. The field cage will be a box-like apparatus consisting of two parallel metal plates connected with a resistor chain and attached to wires wrapped between them. The cage will provide a uniform electric field within the chamber to drift electrons from nuclear reactions down to the detector in the bottom of the chamber. These signals are then amplified by a proportional counter, and the data is sent to a computer. For the long term, we would like to incorporate a Micro-Pattern Gas Detectors in the interior of the chamber and eventually use the AT-TPC to examine various nuclei. Dr. Ahn is my advising professor.

  17. MBE growth of active regions for electrically pumped, cw-operating GaSb-based VCSELs

    NASA Astrophysics Data System (ADS)

    Kashani-Shirazi, K.; Bachmann, A.; Boehm, G.; Ziegler, S.; Amann, M.-C.

    2009-03-01

    Electrically pumped, cw-operating, single-mode GaSb-based VCSELs are attractive light sources for trace-gas sensing systems using tunable diode laser absorption spectroscopy (TDLAS) [A. Vicet, D.A. Yarekha, A. Pérona, Y. Rouillard, S. Gaillard, Spectrochimica Acta Part A 58 (2002) 2405-2412]. Only recently, the first electrically pumped (EP) devices emitting at 2.325 μm in cw-mode at room temperature have been reported [A. Bachmann, T. Lim, K. Kashani-Shirazi, O. Dier, C. Lauer, M.-C. Amann, Electronics Letters 44(3) (2008) 202-203]. The fabrication of these devices employs the molecular beam epitaxy (MBE) growth of GaSb/AlAsSb-distributed Bragg mirrors, a multi-quantum-well active region made of AlGaAsSb/InGaAsSb and an InAsSb/GaSb-buried-tunnel junction. As VCSELs are usually driven under high injection rates, an optimum electrical design of active regions is essential for high-performance devices. In this paper we present an enhanced simulation of current flow in the active region under operation conditions. The calculation includes carrier transport by drift, diffusion and tunneling. We discuss different design criteria and material compositions for active regions. Active regions with various barrier materials were incorporated into edge emitter samples to evaluate their performance. Aluminum-containing barriers show better internal efficiency compared to active regions with GaSb as the barrier material.

  18. Optical Properties of Active Regions in Terahertz Quantum Cascade Lasers

    NASA Astrophysics Data System (ADS)

    Dyksik, M.; Motyka, M.; Rudno-Rudziński, W.; Sęk, G.; Misiewicz, J.; Pucicki, D.; Kosiel, K.; Sankowska, I.; Kubacka-Traczyk, J.; Bugajski, M.

    2016-07-01

    In this work, AlGaAs/GaAs superlattice, with layers' sequence and compositions imitating the active and injector regions of a quantum cascade laser designed for emission in the terahertz spectral range, was investigated. Three independent absorption-like optical spectroscopy techniques were employed in order to study the band structure of the minibands formed within the conduction band. Photoreflectance measurements provided information about interband transitions in the investigated system. Common transmission spectra revealed, in the target range of intraband transitions, mainly a number of lines associated with the phonon-related processes, including two-phonon absorption. In contrast, differential transmittance realized by means of Fourier-transform spectroscopy was utilized to probe the confined states of the conduction band. The obtained energy separation between the second and third confined electron levels, expected to be predominantly contributing to the lasing, was found to be ~9 meV. The optical spectroscopy measurements were supported by numerical calculations performed in the effective mass approximation and XRD measurements for layers' width verification. The calculated energy spacings are in a good agreement with the experimental values.

  19. Eruptions that Drive Coronal Jets in a Solar Active Region

    NASA Technical Reports Server (NTRS)

    Sterling, Alphonse C.; Moore, Ronald L.; Falconer, David A.; Panesar, Navdeep K.; Akiyama, Sachiko; Yashiro, Seiji; Gopalswamy, Nat

    2016-01-01

    Solar coronal jets are common in both coronal holes and in active regions (e.g., Shibata et al. 1992, Shimojo et al. 1996, Cirtain et al. 2007. Savcheva et al. 2007). Recently, Sterling et al. (2015), using data from Hinode/XRT and SDO/AIA, found that coronal jets originating in polar coronal holes result from the eruption of small-scale filaments (minifilaments). The jet bright point (JBP) seen in X-rays and hotter EUV channels off to one side of the base of the jet's spire develops at the location where the minifilament erupts, consistent with the JBPs being miniature versions of typical solar flares that occur in the wake of large-scale filament eruptions. Here we consider whether active region coronal jets also result from the same minifilament-eruption mechanism, or whether they instead result from a different mechanism (e.g. Yokoyama & Shibata 1995). We present observations of an on-disk active region (NOAA AR 11513) that produced numerous jets on 2012 June 30, using data from SDO/AIA and HMI, and from GOES/SXI. We find that several of these active region jets also originate with eruptions of miniature filaments (size scale 20'') emanating from small-scale magnetic neutral lines of the region. This demonstrates that active region coronal jets are indeed frequently driven by minifilament eruptions. Other jets from the active region were also consistent with their drivers being minifilament eruptions, but we could not confirm this because the onsets of those jets were hidden from our view. This work was supported by funding from NASA/LWS, NASA/HGI, and Hinode. A full report of this study appears in Sterling et al. (2016).

  20. Thermal design for areas of interference heating on actively cooled hypersonic aircraft

    NASA Technical Reports Server (NTRS)

    Herring, R. L.; Stone, J. E.

    1978-01-01

    Numerous actively cooled panel design alternatives for application in regions on high speed aircraft that are subject to interference heating effects were studied. Candidate design concepts were evaluated using mass, producibility, reliability and inspectability/maintainability as figures of merit. Three design approaches were identified as superior within certain regimes of the matrix of design heating conditions considered. Only minor modifications to basic actively cooled panel design are required to withstand minor interference heating effects. Designs incorporating internally finned coolant tubes to augment heat transfer are recommended for moderate design heating conditions. At severe heating conditions, an insulated panel concept is required.

  1. Regional Design Approach in Designing Climatic Responsive Administrative Building in the 21st Century

    NASA Astrophysics Data System (ADS)

    Haja Bava Mohidin, Hazrina Binti; Ismail, Alice Sabrina

    2015-01-01

    The objective of this paper is to explicate on the study of modern administrative building in Malaysia which portrays regional design approach that conforms to the local context and climate by reviewing two case studies; Perdana Putra (1999) and former Prime Minister's Office (1967). This paper is significant because the country's stature and political statement was symbolized by administrative building as a national icon. In other words, it is also viewed as a cultural object that is closely tied to a particular social context and nation historical moment. Administrative building, therefore, may exhibit various meanings. This paper uses structuralism paradigm and semiotic principles as a methodological approach. This paper is of importance for practicing architects and society in the future as it offers new knowledge and understanding in identifying the suitable climatic consideration that may reflect regionalist design approach in modern administrative building. These elements then may be adopted in designing public buildings in the future with regional values that are important for expressing national culture to symbolize the identity of place and society as well as responsive to climate change.

  2. THz quantum cascade lasers with wafer bonded active regions.

    PubMed

    Brandstetter, M; Deutsch, C; Benz, A; Cole, G D; Detz, H; Andrews, A M; Schrenk, W; Strasser, G; Unterrainer, K

    2012-10-01

    We demonstrate terahertz quantum-cascade lasers with a 30 μm thick double-metal waveguide, which are fabricated by stacking two 15 μm thick active regions using a wafer bonding process. By increasing the active region thickness more optical power is generated inside the cavity, the waveguide losses are decreased and the far-field is improved due to a larger facet aperture. In this way the output power is increased by significantly more than a factor of 2 without reducing the maximum operating temperature and without increasing the threshold current.

  3. Kink Waves in an Active Region Dynamic Fibril

    NASA Astrophysics Data System (ADS)

    Pietarila, A.; Aznar Cuadrado, R.; Hirzberger, J.; Solanki, S. K.

    2011-10-01

    We present high spatial and temporal resolution Ca II 8542 Å observations of a kink wave in an on-disk chromospheric active region fibril. The properties of the wave are similar to those observed in off-limb spicules. From the observed phase and period of the wave we determine a lower limit for the field strength in the chromospheric active region fibril located at the edge of a sunspot to be a few hundred gauss. We find indications that the event was triggered by a small-scale reconnection event higher up in the atmosphere.

  4. Local and Regional Authorities as Resources for Implementing Universal Design Policy in Norway.

    PubMed

    Lund, Einar

    2016-01-01

    The municipalities and regional authorities are in general resources for achieving national goals. Their management and works are crucial to the development and implementation of Universal Design. Through several programmes, national authorities have worked for activating the local and regional levels. The results are visible. We can see a long-term national strategy to help make society accessible to everyone and prevent discrimination. Participating municipalities and regional authorities are now able to create their own policy and strategies and implement solutions. The national programs have involved interested and motivated municipalities. All the 18 counties in Norway have been involved more or less in different periods and the same with up to a third of the about good 400 municipalities. PMID:27534287

  5. Local and Regional Authorities as Resources for Implementing Universal Design Policy in Norway.

    PubMed

    Lund, Einar

    2016-01-01

    The municipalities and regional authorities are in general resources for achieving national goals. Their management and works are crucial to the development and implementation of Universal Design. Through several programmes, national authorities have worked for activating the local and regional levels. The results are visible. We can see a long-term national strategy to help make society accessible to everyone and prevent discrimination. Participating municipalities and regional authorities are now able to create their own policy and strategies and implement solutions. The national programs have involved interested and motivated municipalities. All the 18 counties in Norway have been involved more or less in different periods and the same with up to a third of the about good 400 municipalities.

  6. Extravehicular activity training and hardware design consideration.

    PubMed

    Thuot, P J; Harbaugh, G J

    1995-07-01

    Preparing astronauts to perform the many complex extravehicular activity (EVA) tasks required to assemble and maintain Space Station will be accomplished through training simulations in a variety of facilities. The adequacy of this training is dependent on a thorough understanding of the task to be performed, the environment in which the task will be performed, high-fidelity training hardware and an awareness of the limitations of each particular training facility. Designing hardware that can be successfully operated, or assembled, by EVA astronauts in an efficient manner, requires an acute understanding of human factors and the capabilities and limitations of the space-suited astronaut. Additionally, the significant effect the microgravity environment has on the crew members' capabilities has to be carefully considered not only for each particular task, but also for all the overhead related to the task and the general overhead associated with EVA. This paper will describe various training methods and facilities that will be used to train EVA astronauts for Space Station assembly and maintenance. User-friendly EVA hardware design considerations and recent EVA flight experience will also be presented. PMID:11541312

  7. Extravehicular activity training and hardware design consideration.

    PubMed

    Thuot, P J; Harbaugh, G J

    1995-07-01

    Preparing astronauts to perform the many complex extravehicular activity (EVA) tasks required to assemble and maintain Space Station will be accomplished through training simulations in a variety of facilities. The adequacy of this training is dependent on a thorough understanding of the task to be performed, the environment in which the task will be performed, high-fidelity training hardware and an awareness of the limitations of each particular training facility. Designing hardware that can be successfully operated, or assembled, by EVA astronauts in an efficient manner, requires an acute understanding of human factors and the capabilities and limitations of the space-suited astronaut. Additionally, the significant effect the microgravity environment has on the crew members' capabilities has to be carefully considered not only for each particular task, but also for all the overhead related to the task and the general overhead associated with EVA. This paper will describe various training methods and facilities that will be used to train EVA astronauts for Space Station assembly and maintenance. User-friendly EVA hardware design considerations and recent EVA flight experience will also be presented.

  8. Socioeconomic and regional differences in active transportation in Brazil

    PubMed Central

    de Sá, Thiago Hérick; Pereira, Rafael Henrique Moraes; Duran, Ana Clara; Monteiro, Carlos Augusto

    2016-01-01

    ABSTRACT OBJECTIVE To present national estimates regarding walking or cycling for commuting in Brazil and in 10 metropolitan regions. METHODS By using data from the Health section of 2008’s Pesquisa Nacional por Amostra de Domicílio (Brazil’s National Household Sample Survey), we estimated how often employed people walk or cycle to work, disaggregating our results by sex, age range, education level, household monthly income per capita, urban or rural address, metropolitan regions, and macro-regions in Brazil. Furthermore, we estimated the distribution of this same frequency according to quintiles of household monthly income per capita in each metropolitan region of the country. RESULTS A third of the employed men and women walk or cycle from home to work in Brazil. For both sexes, this share decreases as income and education levels rise, and it is higher among younger individuals, especially among those living in rural areas and in the Northeast region of the country. Depending on the metropolitan region, the practice of active transportation is two to five times more frequent among low-income individuals than among high-income individuals. CONCLUSIONS Walking or cycling to work in Brazil is most frequent among low-income individuals and the ones living in less economically developed areas. Active transportation evaluation in Brazil provides important information for public health and urban mobility policy-making PMID:27355465

  9. IFLA General Conference, 1989. Division of Regional Activities. Section on Regional Activities--Africa; Section on Regional Activities--Asia and Oceania; Section on Regional Activities--Latin America and the Caribbean. Booklet 80.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    There are five papers in this collection from the Division of Regional Activities: (1) "Communication and Information in Contemporary African Society" (Bimpe Aboyade), which discusses how libraries can make themselves relevant to other institutions concerned with information transfer; (2) "Libraries and Rural Development: Village Reading Rooms in…

  10. Inferred flows of electric currents in solar active regions

    NASA Technical Reports Server (NTRS)

    Ding, Y. J.; Hong, Q. F.; Hagyard, M. J.; Deloach, A. C.

    1985-01-01

    Techniques to identify sources of major current systems in active regions and their channels of flow are explored. Measured photospheric vector magnetic fields together with high resolution white light and H-alpha photographs provide the data base to derive the current systems in the photosphere and chromosphere of a solar active region. Simple mathematical constructions of active region fields and currents are used to interpret these data under the assumptions that the fields in the lower atmosphere (below 200 km) may not be force free but those in the chromosphere and higher are. The results obtained for the complex active region AR 2372 are: (1) Spots exhibiting significant spiral structure in the penumbral filaments were the source of vertical currents at the photospheric surface; (2) Magnetic neutral lines where the transverse magnetic field was strongly sheared were channels along which a strong current system flowed; (3) The inferred current systems produced a neutral sheet and oppositely-flowing currents in the area of the magnetic delta configuration that was the site of flaring.

  11. IFLA General Conference, 1987. Division of Regional Activities. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    Six of the seven papers in this collection focus on regional library activities in Africa, Asia and Oceania, and Latin America and the Caribbean: (1) "Libraries and Information Services in a Changing World: The Challenges African Information Services Face at the End of the 1980s" (Dejen Abate, Ethiopia); (2) "The Computer and Knowledge Information…

  12. Urban, Rural, and Regional Variations in Physical Activity

    ERIC Educational Resources Information Center

    Martin, Sarah Levin; Kirkner, Gregory J.; Mayo, Kelly; Matthews, Charles E.; Durstine, J. Larry; Hebert, James R.

    2005-01-01

    Purpose: There is some speculation about geographic differences in physical activity (PA) levels. We examined the prevalence of physical inactivity (PIA) and whether US citizens met the recommended levels of PA across the United States. In addition, the association between PIA/PA and degree of urbanization in the 4 main US regions (Northeast,…

  13. Early life stress affects limited regional brain activity in depression.

    PubMed

    Du, Lian; Wang, Jingjie; Meng, Ben; Yong, Na; Yang, Xiangying; Huang, Qingling; Zhang, Yan; Yang, Lingling; Qu, Yuan; Chen, Zhu; Li, Yongmei; Lv, Fajin; Hu, Hua

    2016-05-03

    Early life stress (ELS) can alter brain function and increases the risk of major depressive disorder (MDD) in later life. This study investigated whether ELS contributes to differences in regional brain activity between MDD patients and healthy controls (HC), as measured by amplitude of low-frequency fluctuation (ALFF)/fractional (f)ALFF. Eighteen first-episode, treatment-naïve MDD patients and HC were assessed with the Childhood Trauma Questionnaire and resting-state functional magnetic resonance imaging. We compared ALFF/fALFF between MDD patients and HC, with or without controlling for ELS, and determined whether ELS level was correlated with regional brain activity in each group. After regressing out ELS, we found that ALFF increased in bilateral amygdala and left orbital/cerebellum, while fALFF decreased in left inferior temporal and right middle frontal gyri in MDD patients relative to controls. ELS positively correlated with regional activity in the left cerebellum in MDD and in the right post-central/inferior temporal/superior frontal cingulate, inferior frontal gyrus and bilateral cerebellum in HC. Our findings indicate that there is only very limited region showing correlation between ELS and brain activity in MDD, while diverse areas in HC, suggesting ELS has few impacts on MDD patients.

  14. A solar cycle timing predictor - The latitude of active regions

    NASA Technical Reports Server (NTRS)

    Schatten, Kenneth H.

    1990-01-01

    A 'Spoerer butterfly' method is used to examine solar cycle 22. It is shown from the latitude of active regions that the cycle can now be expected to peak near November 1989 + or - 8 months, basically near the latter half of 1989.

  15. Unwinding motion of a twisted active region filament

    SciTech Connect

    Yan, X. L.; Xue, Z. K.; Kong, D. F.; Liu, J. H.; Xu, C. L.

    2014-12-10

    To better understand the structures of active region filaments and the eruption process, we study an active region filament eruption in active region NOAA 11082 in detail on 2010 June 22. Before the filament eruption, the opposite unidirectional material flows appeared in succession along the spine of the filament. The rising of the filament triggered two B-class flares at the upper part of the filament. As the bright material was injected into the filament from the sites of the flares, the filament exhibited a rapid uplift accompanying the counterclockwise rotation of the filament body. From the expansion of the filament, we can see that the filament consisted of twisted magnetic field lines. The total twist of the filament is at least 5π obtained by using a time slice method. According to the morphology change during the filament eruption, it is found that the active region filament was a twisted flux rope and its unwinding motion was like a solar tornado. We also find that there was a continuous magnetic helicity injection before and during the filament eruption. It is confirmed that magnetic helicity can be transferred from the photosphere to the filament. Using the extrapolated potential fields, the average decay index of the background magnetic fields over the filament is 0.91. Consequently, these findings imply that the mechanism of solar filament eruption could be due to the kink instability and magnetic helicity accumulation.

  16. Early life stress affects limited regional brain activity in depression

    PubMed Central

    Du, Lian; Wang, Jingjie; Meng, Ben; Yong, Na; Yang, Xiangying; Huang, Qingling; Zhang, Yan; Yang, Lingling; Qu, Yuan; Chen, Zhu; Li, Yongmei; Lv, Fajin; Hu, Hua

    2016-01-01

    Early life stress (ELS) can alter brain function and increases the risk of major depressive disorder (MDD) in later life. This study investigated whether ELS contributes to differences in regional brain activity between MDD patients and healthy controls (HC), as measured by amplitude of low-frequency fluctuation (ALFF)/fractional (f)ALFF. Eighteen first-episode, treatment-naïve MDD patients and HC were assessed with the Childhood Trauma Questionnaire and resting-state functional magnetic resonance imaging. We compared ALFF/fALFF between MDD patients and HC, with or without controlling for ELS, and determined whether ELS level was correlated with regional brain activity in each group. After regressing out ELS, we found that ALFF increased in bilateral amygdala and left orbital/cerebellum, while fALFF decreased in left inferior temporal and right middle frontal gyri in MDD patients relative to controls. ELS positively correlated with regional activity in the left cerebellum in MDD and in the right post-central/inferior temporal/superior frontal cingulate, inferior frontal gyrus and bilateral cerebellum in HC. Our findings indicate that there is only very limited region showing correlation between ELS and brain activity in MDD, while diverse areas in HC, suggesting ELS has few impacts on MDD patients. PMID:27138376

  17. Evolution of two Flaring Active Regions With CME Association

    NASA Astrophysics Data System (ADS)

    Thalmann, J. K.; Wiegelmann, T.

    2008-12-01

    We study the coronal magnetic field structure of two active regions, one during solar activity minimum (June 2007) and another one during a more active time (January 2004). The temporal evolution was explored with the help of nonlinear force-free coronal magnetic field extrapolations of SOLIS/VSM and NAOJ/SFT photospheric vector magnetograms. We study the active region NOAA 10960 observed on 2007 June 7 with three SOLIS/VSM snapshots taken during a small C1.0 flare of time cadence 10 minutes and six snapshots during a quiet period. The total magnetic energy in the active region was approximately 3 × 1025 J. Before the flare the free magnetic energy was about 5~% of the potential field energy. A part of this excess energy was released during the flare, producing almost a potential configuration at the beginning of the quiet period. The return to an almost potential structure can be assigned to a CME as recorded by the SoHO/LASCO instrument on 2007 June 07 around 10 minutes after the flare peaked, so that whatever magnetic helicity was bodily removed from the structure. This was compared with active region 10540 observed on 2004 January 18 -- 21, which was analyzed with the help of vector magnetograph data from the Solar Flare Telescope in Japan of time cadence of about 1 day. The free energy was Efree≈ 66~% of the total energy which was sufficiently high to power a M6.1 flare on January 20, which was associated with a CME 20 minutes later. The activity of AR 10540 was significantly higher than for AR 10960, as was the total magnetic energy. Furthermore, we found the common feature that magnetic energy accumulates before the flare/CME and a significant part of the excess energy is released during the eruption.

  18. Regional differences in rat conjunctival ion transport activities

    PubMed Central

    Yu, Dongfang; Thelin, William R.; Rogers, Troy D.; Stutts, M. Jackson; Randell, Scott H.; Grubb, Barbara R.

    2012-01-01

    Active ion transport and coupled osmotic water flow are essential to maintain ocular surface health. We investigated regional differences in the ion transport activities of the rat conjunctivas and compared these activities with those of cornea and lacrimal gland. The epithelial sodium channel (ENaC), sodium/glucose cotransporter 1 (Slc5a1), transmembrane protein 16 (Tmem16a, b, f, and g), cystic fibrosis transmembrane conductance regulator (Cftr), and mucin (Muc4, 5ac, and 5b) mRNA expression was characterized by RT-PCR. ENaC proteins were measured by Western blot. Prespecified regions (palpebral, fornical, and bulbar) of freshly isolated conjunctival tissues and cell cultures were studied electrophysiologically with Ussing chambers. The transepithelial electrical potential difference (PD) of the ocular surface was also measured in vivo. The effect of amiloride and UTP on the tear volume was evaluated in lacrimal gland excised rats. All selected genes were detected but with different expression patterns. We detected αENaC protein in all tissues, βENaC in palpebral and fornical conjunctiva, and γENaC in all tissues except lacrimal glands. Electrophysiological studies of conjunctival tissues and cell cultures identified functional ENaC, SLC5A1, CFTR, and TMEM16. Fornical conjunctiva exhibited the most active ion transport under basal conditions amongst conjunctival regions. PD measurements confirmed functional ENaC-mediated Na+ transport on the ocular surface. Amiloride and UTP increased tear volume in lacrimal gland excised rats. This study demonstrated that the different regions of the conjunctiva exhibited a spectrum of ion transport activities. Understanding the specific functions of distinct regions of the conjunctiva may foster a better understanding of the physiology maintaining hydration of the ocular surface. PMID:22814399

  19. Active sonar, beaked whales and European regional policy.

    PubMed

    Dolman, Sarah J; Evans, Peter G H; Notarbartolo-di-Sciara, Giuseppe; Frisch, Heidrun

    2011-01-01

    Various reviews, resolutions and guidance from international and regional fora have been produced in recent years that acknowledge the significance of marine noise and its potential impacts on cetaceans. Within Europe, ACCOBAMS and ASCOBANS have shown increasing attention to the issue. The literature highlights concerns surrounding the negative impacts of active sonar on beaked whales in particular, where concerns primarily relate to the use of mid-frequency active sonar (1-10kHz), as used particularly in military exercises. The authors review the efforts that European regional policies have undertaken to acknowledge and manage possible negative impacts of active sonar and how these might assist the transition from scientific research to policy implementation, including effective management and mitigation measures at a national level.

  20. Patterns of Activity Revealed by a Time Lag Analysis of a Model Active Region

    NASA Astrophysics Data System (ADS)

    Bradshaw, Stephen; Viall, Nicholeen

    2016-05-01

    We investigate the global activity patterns predicted from a model active region heated by distributions of nanoflares that have a range of average frequencies. The activity patterns are manifested in time lag maps of narrow-band instrument channel pairs. We combine an extrapolated magnetic skeleton with hydrodynamic and forward modeling codes to create a model active region, and apply the time lag method to synthetic observations. Our aim is to recover some typical properties and patterns of activity observed in active regions. Our key findings are: 1. Cooling dominates the time lag signature and the time lags between the channel pairs are generally consistent with observed values. 2. Shorter coronal loops in the core cool more quickly than longer loops at the periphery. 3. All channel pairs show zero time lag when the line-of-sight passes through coronal loop foot-points. 4. There is strong evidence that plasma must be re-energized on a time scale comparable to the cooling timescale to reproduce the observed coronal activity, but it is likely that a relatively broad spectrum of heating frequencies operates across active regions. 5. Due to their highly dynamic nature, we find nanoflare trains produce zero time lags along entire flux tubes in our model active region that are seen between the same channel pairs in observed active regions.

  1. A Guide to Microsoft Active Directory (AD) Design

    SciTech Connect

    Dias, J

    2002-04-29

    The goal of this paper is to facilitate the design process for those DOE sites that are currently engaged in designing their Active Directory (AD) network. It is a roadmap to enable analysis of the complicated design tradeoffs associated with Active Directory Design. By providing discussion of Active Directory design elements which are permanent and costly to change once deployed, the hope is to minimize the risks of sponsoring failed designs, or joining existing infrastructures not suitable to programmatic needs. Specifically, most Active Directory structures will fall under one of three common designs: Single Domain, Single Forest with Multiple Domains, or Multiple Forests. Each has benefits and concerns, depending on programmatic and organizational structures. The comparison of these three approaches will facilitate almost any Active Directory design effort. Finally, this paper describes some best practices to consider when designing Active Directory based on three years of research and experience.

  2. Directory of International and Regional Organizations Conducting Standards-Related Activities, May 1989

    NASA Astrophysics Data System (ADS)

    Breitenberg, Maureen

    1989-05-01

    The directory contains information on 338 international and regional organizations which conduct standardization, certification, laboratory accreditation, or other standards-related activities. The volume describes their work in these areas, the scope of each organization, national affliations of members, U.S. participants, restrictions on membership, as well as the availability of any standards in English. The volume is designed to serve the needs of Federal agencies and standards writers for information on international and regional organizations involved in standardization and related activities. It may also be useful to manufacturers, engineers, purchasing agents, and others.

  3. 8 CFR 335.12 - Recommendations on petitions for naturalization of the designated examiner and regional...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... naturalization of the designated examiner and regional administrator; notice. 335.12 Section 335.12 Aliens and... NATURALIZATION § 335.12 Recommendations on petitions for naturalization of the designated examiner and regional... naturalization filed prior to October 1, 1991, the designated examiner shall prepare an...

  4. 8 CFR 335.12 - Recommendations on petitions for naturalization of the designated examiner and regional...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... naturalization of the designated examiner and regional administrator; notice. 335.12 Section 335.12 Aliens and... NATURALIZATION § 335.12 Recommendations on petitions for naturalization of the designated examiner and regional... naturalization filed prior to October 1, 1991, the designated examiner shall prepare an...

  5. DIVERGENT HORIZONTAL SUB-SURFACE FLOWS WITHIN ACTIVE REGION 11158

    SciTech Connect

    Jain, Kiran; Tripathy, S. C.; Hill, F. E-mail: stripathy@nso.edu

    2015-07-20

    We measure the horizontal subsurface flow in a fast emerging active region (AR; NOAA 11158) using the ring-diagram technique and the Helioseismic and Magnetic Imager high spatial resolution Dopplergrams. This AR had a complex magnetic structure and displayed significant changes in morphology during its disk passage. Over a period of six days from 2011 February 11 to 16, the temporal variation in the magnitude of the total velocity is found to follow the trend of magnetic field strength. We further analyze regions of individual magnetic polarity within AR 11158 and find that the horizontal velocity components in these sub-regions have significant variation with time and depth. The leading and trailing polarity regions move faster than the mixed-polarity region. Furthermore, both zonal and meridional components have opposite signs for trailing and leading polarity regions at all depths showing divergent flows within the AR. We also find a sharp decrease in the magnitude of total horizontal velocity in deeper layers around major flares. It is suggested that the re-organization of magnetic fields during flares, combined with the sunspot rotation, decreases the magnitude of horizontal flows or that the flow kinetic energy has been converted into the energy released by flares. After the decline in flare activity and sunspot rotation, the flows tend to follow the pattern of magnetic activity. We also observe less variation in the velocity components near the surface but these tend to increase with depth, further demonstrating that the deeper layers are more affected by the topology of ARs.

  6. THE EVOLUTION OF DARK CANOPIES AROUND ACTIVE REGIONS

    SciTech Connect

    Wang, Y.-M.; Robbrecht, E.; Muglach, K. E-mail: eva.robbrecht@oma.be

    2011-05-20

    As observed in spectral lines originating from the chromosphere, transition region, and low corona, active regions are surrounded by an extensive 'circumfacular' area which is darker than the quiet Sun. We examine the properties of these dark moat- or canopy-like areas using Fe IX 17.1 nm images and line-of-sight magnetograms from the Solar Dynamics Observatory. The 17.1 nm canopies consist of fibrils (horizontal fields containing extreme-ultraviolet-absorbing chromospheric material) clumped into featherlike structures. The dark fibrils initially form a quasiradial or vortical pattern as the low-lying field lines fanning out from the emerging active region connect to surrounding network and intranetwork elements of opposite polarity. The area occupied by the 17.1 nm fibrils expands as supergranular convection causes the active-region flux to spread into the background medium; the outer boundary of the dark canopy stabilizes where the diffusing flux encounters a unipolar region of opposite sign. The dark fibrils tend to accumulate in regions of weak longitudinal field and to become rooted in mixed-polarity flux. To explain the latter observation, we note that the low-lying fibrils are more likely to interact with small loops associated with weak, opposite-polarity flux elements in close proximity, than with high loops anchored inside strong unipolar network flux. As a result, the 17.1 nm fibrils gradually become concentrated around the large-scale polarity inversion lines (PILs), where most of the mixed-polarity flux is located. Systematic flux cancellation, assisted by rotational shearing, removes the field component transverse to the PIL and causes the fibrils to coalesce into long PIL-aligned filaments.

  7. Design of a turbofan powered regional transport aircraft

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The majority of the market for small commercial transport aircraft is dominated by high efficiency propeller driven aircraft of non-U.S. manufacture. During the past year, an aircraft was designed with ranges of up to 1500 nautical miles and passenger loads between 50 and 90. Special emphasis was placed upon keeping acquisition cost and direct operating costs at a low level while providing passengers with quality comfort levels. Several designs are presented which place a high premium on design innovation.

  8. Fine thermal structure of a coronal active region.

    PubMed

    Reale, Fabio; Parenti, Susanna; Reeves, Kathy K; Weber, Mark; Bobra, Monica G; Barbera, Marco; Kano, Ryouhei; Narukage, Noriyuki; Shimojo, Masumi; Sakao, Taro; Peres, Giovanni; Golub, Leon

    2007-12-01

    The determination of the fine thermal structure of the solar corona is fundamental to constraining the coronal heating mechanisms. The Hinode X-ray Telescope collected images of the solar corona in different passbands, thus providing temperature diagnostics through energy ratios. By combining different filters to optimize the signal-to-noise ratio, we observed a coronal active region in five filters, revealing a highly thermally structured corona: very fine structures in the core of the region and on a larger scale further away. We observed continuous thermal distribution along the coronal loops, as well as entangled structures, and variations of thermal structuring along the line of sight.

  9. Armenia as a Regional Centre for Astronomy for Development activities

    NASA Astrophysics Data System (ADS)

    Mickaelian, A.

    2015-03-01

    The Byurakan Astrophysical Observatory (BAO, Armenia, http://www.bao.am) are among the candidate IAU Regional Nodes for Astronomy for Development activities. It is one of the main astronomical centers of the former Soviet Union and the Middle East region. At present there are 48 qualified researchers at BAO, including six Doctors of Science and 30 PhDs. Five important observational instruments are installed at BAO, the larger ones being 2.6m Cassegrain (ZTA-2.6) and 1m Schmidt (the one that provided the famous Markarian survey). BAO is regarded as a national scientific-educational center, where a number of activities are being organized, such as: international conferences (4 IAU symposia and 1 IAU colloquium, JENAM-2007, etc.), small workshops and discussions, international summer schools (1987, 2006, 2008 and 2010), and Olympiads. BAO collaborates with scientists from many countries. The Armenian Astronomical Society (ArAS, http://www.aras.am/) is an NGO founded in 2001; it has 93 members and it is rather active in the organization of educational, amateur, popular, promotional and other matters. The Armenian Virtual Observatory (ArVO, http://www.aras.am/Arvo/arvo.htm) is one of the 17 national VO projects forming the International Virtual Observatories Alliance (IVOA) and is the only VO project in the region serving also for educational purposes. A number of activities are planned, such as management, coordination and evaluation of the IAU programs in the area of development and education, establishment of the new IAU endowed lectureship program and organization of seminars and public lectures, coordination and initiation of fundraising activities for astronomy development, organization of regional scientific symposia, conferences and workshops, support to Galileo Teacher Training Program (GTTP), production/publication of educational and promotional materials, etc.

  10. Structure and polarization of active region microwave emission

    NASA Technical Reports Server (NTRS)

    Kundu, M. R.; Alissandrakis, C. E.

    1984-01-01

    Active region radio emission observations made at 6.16 cm wavelength during May 20-27, 1980, are the bases of maps of total intensity and circular polarization presented for the three regions whose Hale numbers are 16850, 16863, and 16864. A detailed comparison is made between these maps and on- and off-band H-alpha pictures and magnetograms. The neutral lines with which the strongest sources were associated have their two opposite polarities close to each other, implying a high magnetic field gradient, and are also associated with arch filament systems. A detailed analysis is undertaken of observations of the circular polarization sense inversion in region 16863. The large scale structure of the magnetic field can be approximated by a dipole with its axis inclined by 11 deg with respect to the photosphere, and with a dipole moment of about 2 x 10 to the 31 power cgs units.

  11. IPS observations of heliospheric density structures associated with active regions

    NASA Technical Reports Server (NTRS)

    Hick, P.; Jackson, B. V.; Altrock, R.; Woan, G.; Slater, G.

    1996-01-01

    Interplanetary scintillation (IPS) measurements of the 'disturbance factor' g, obtained with the Cambridge (UK) array can be used to explore the heliospheric density structure. We have used these data to construct synoptic (Carrington) maps, representing the large-scale enhancements of the g-factor in the inner heliosphere. These maps emphasize the stable corotating, rather than the transient heliospheric density enhancements. We have compared these maps with Carrington maps of Fe XIV observations National Solar Observatory ((NSO), Sacramento Peak) and maps based on Yohkoh Soft X-Ray Telescope (SXT) X-ray observations. Our results indicate that the regions of enhanced g tend to map to active regions rather than the current sheet. The implication is that act ve regions are the dominant source of the small-scale (approximately equal 200 km) density variations present in the quiet solar wind.

  12. Active region upflows. I. Multi-instrument observations

    NASA Astrophysics Data System (ADS)

    Vanninathan, K.; Madjarska, M. S.; Galsgaard, K.; Huang, Z.; Doyle, J. G.

    2015-12-01

    Context. We study upflows at the edges of active regions, called AR outflows, using multi-instrument observations. Aims: This study intends to provide the first direct observational evidence of whether chromospheric jets play an important role in furnishing mass that could sustain coronal upflows. The evolution of the photospheric magnetic field, associated with the footpoints of the upflow region and the plasma properties of active region upflows is investigated with the aim of providing information for benchmarking data-driven modelling of this solar feature. Methods: We spatially and temporally combine multi-instrument observations obtained with the Extreme-ultraviolet Imaging Spectrometer on board the Hinode, the Atmospheric Imaging Assembly and the Helioseismic Magnetic Imager instruments on board the Solar Dynamics Observatory and the Interferometric BI-dimensional Spectro-polarimeter installed at the National Solar Observatory, Sac Peak, to study the plasma parameters of the upflows and the impact of the chromosphere on active region upflows. Results: Our analysis shows that the studied active region upflow presents similarly to those studied previously, i.e. it displays blueshifted emission of 5-20 kms-1 in Fe xii and Fe xiii and its average electron density is 1.8 × 109 cm-3 at 1 MK. The time variation of the density is obtained showing no significant change (in a 3σ error). The plasma density along a single loop is calculated revealing a drop of 50% over a distance of ~20 000 km along the loop. We find a second velocity component in the blue wing of the Fe xii and Fe xiii lines at 105 kms-1 reported only once before. For the first time we study the time evolution of this component at high cadence and find that it is persistent during the whole observing period of 3.5 h with variations of only ±15 kms-1. We also, for the first time, study the evolution of the photospheric magnetic field at high cadence and find that magnetic flux diffusion is

  13. Diagnostics of Coronal Heating in Solar Active Regions

    NASA Astrophysics Data System (ADS)

    Fludra, Andrzej; Hornsey, Christopher; Nakariakov, Valery

    2015-04-01

    We aim to develop a diagnostic method for the coronal heating mechanism in active region loops. Observational constraints on coronal heating models have been sought using measurements in the X-ray and EUV wavelengths. Statistical analysis, using EUV emission from many active regions, was done by Fludra and Ireland (2008) who studied power-law relationships between active region integrated magnetic flux and emission line intensities. A subsequent study by Fludra and Warren (2010) for the first time compared fully resolved images in an EUV spectral line of OV 63.0 nm with the photospheric magnetic field, leading to the identification of a dominant, ubiquitous variable component of the transition region EUV emission and a discovery of a steady basal heating, and deriving the dependence of the basal heating rate on the photospheric magnetic flux density. In this study, we compare models of single coronal loops with EUV observations. We assess to what degree observations of individual coronal loops made in the EUV range are capable of providing constraints on the heating mechanism. We model the coronal magnetic field in an active region using an NLFF extrapolation code applied to a photospheric vector magnetogram from SDO/HMI and select several loops that match an SDO/AIA 171 image of the same active region. We then model the plasma in these loops using a 1D hydrostatic code capable of applying an arbitrary heating rate as a function of magnetic field strength along the loop. From the plasma parameters derived from this model, we calculate the EUV emission along the loop in AIA 171 and 335 bands, and in pure spectral lines of Fe IX 17.1 nm and Fe XVI 33.5 nm. We use different spatial distributions of the heating function: concentrated near the loop top, uniform and concentrated near the footpoints, and investigate their effect on the modelled EUV intensities. We find a diagnostics based on the dependence of the total loop intensity on the shape of the heating function

  14. Electron acceleration and radiation in evolving complex active regions

    NASA Astrophysics Data System (ADS)

    Anastasiadis, A.; Gontikakis, C.; Vilmer, N.; Vlahos, L.

    2004-07-01

    We present a model for the acceleration and radiation of solar energetic particles (electrons) in evolving complex active regions. The spatio - temporal evolution of active regions is calculated using a cellular automaton model, based on self-organized criticality. The acceleration of electrons is due to the presence of randomly placed, localized electric fields produced by the energy release process, simulated by the cellular automaton model. We calculate the resulting kinetic energy distributions of the particles and their emitted X-ray radiation spectra using the thick target approximation, and we perform a parametric study with respect to number of electric fields present and thermal temperature of the injected distribution. Finally, comparing our results with the existing observations, we find that they are in a good agreement with the observed X-ray spectra in the energy range 100-1000 keV.

  15. Evidence of active region imprints on the solar wind structure

    NASA Technical Reports Server (NTRS)

    Hick, P.; Jackson, B. V.

    1995-01-01

    A common descriptive framework for discussing the solar wind structure in the inner heliosphere uses the global magnetic field as a reference: low density, high velocity solar wind emanates from open magnetic fields, with high density, low speed solar wind flowing outward near the current sheet. In this picture, active regions, underlying closed magnetic field structures in the streamer belt, leave little or no imprint on the solar wind. We present evidence from interplanetary scintillation measurements of the 'disturbance factor' g that active regions play a role in modulating the solar wind and possibly contribute to the solar wind mass output. Hence we find that the traditional view of the solar wind, though useful in understanding many features of solar wind structure, is oversimplified and possibly neglects important aspects of solar wind dynamics

  16. Electric currents and coronal heating in NOAA active region 6952

    NASA Technical Reports Server (NTRS)

    Metcalf, T. R.; Canfield, R. C.; Hudson, H. S.; Mickey, D. L.; Wulser, J. -P.; Martens, P. C. H.; Tsuneta, S.

    1994-01-01

    We examine the spatial and temporal relationship between coronal structures observed with the soft X-ray telescope (SXT) on board the Yohkoh spacecraft and the vertical electric current density derived from photospheric vector magnetograms obtained using the Stokes Polarimeter at the Mees Solar Observatory. We focus on a single active region: AR 6952 which we observed on 7 days during 1991 December. For 11 independent maps of the vertical electric current density co-aligned with non-flaring X-ray images, we search for a morphological relationship between sites of high vertical current density in the photosphere and enhanced X-ray emission in the overlying corona. We find no compelling spatial or temporal correlation between the sites of vertical current and the bright X-ray structures in this active region.

  17. Resolving Behavioral Output via Chemogenetic Designer Receptors Exclusively Activated by Designer Drugs.

    PubMed

    Burnett, C Joseph; Krashes, Michael J

    2016-09-01

    Designer receptors exclusively activated by designer drugs (DREADDs) have proven to be highly effective neuromodulatory tools for the investigation of neural circuits underlying behavioral outputs. They exhibit a number of advantages: they rely on cell-specific manipulations through canonical intracellular signaling pathways, they are easy and cost-effective to implement in a laboratory setting, and they are easily scalable for single-region or full-brain manipulations. On the other hand, DREADDs rely on ligand-G-protein-coupled receptor interactions, leading to coarse temporal dynamics. In this review we will provide a brief overview of DREADDs, their implementation, and the advantages and disadvantages of their use in animal systems. We also will provide numerous examples of their use across a broad variety of biomedical research fields. PMID:27605603

  18. Design of surface-water data networks for regional information

    USGS Publications Warehouse

    Moss, Marshall E.; Gilroy, E.J.; Tasker, Gary D.; Karlinger, M.R.

    1982-01-01

    This report describes a technique, Network Analysis of Regional Information (NARI), and the existing computer procedures that have been developed for the specification of the regional information-cost relation for several statistical parameters of streamflow. The measure of information used is the true standard error of estimate of a regional logarithmic regression. The cost is a function of the number of stations at which hydrologic data are collected and the number of years for which the data are collected. The technique can be used to obtain either (1) a minimum cost network that will attain a prespecified accuracy and reliability or (2) a network that maximizes information given a set of budgetary and time constraints.

  19. Evidence for coronal turbulence in a quiescent active region

    NASA Technical Reports Server (NTRS)

    Saba, Julia L. R.; Strong, Keith T.

    1986-01-01

    The first evidence for nonthermal broadening of X-ray lines in a quiescent active region was based on a single observation of a limb active region by the Flat Crystal Spectrometer (FCS) on the SMM satellite, reported by Acton et al. (1981). With the renewal of SMM operations, the FCS has been used to further investigate this phenomenon. On April 28, 1984 a map of Mg XI resonance line profiles was made for a bright area in NOAA Active Region 4474 during a nonflaring period. The narrowest line profiles are consistent with the nominal instrumental width plus a thermal width equivalent to about 3 million K, the temperature derived from line ratios of O VIII, Ne IX, and Mg XI. The broadest line profiles are consistent with the instrumental width plus a thermal width equivalent to about 7 million K, but a substantial amount of plasma at this temperature would result in much greater flux in the FCS higher-temperature channels than was seen. If the excess width is attributed solely to plasma turbulence, the corresponding velocity would be about 40 + or - 10 km/s.

  20. The Intermediate-line Region in Active Galactic Nuclei

    NASA Astrophysics Data System (ADS)

    Adhikari, T. P.; Różańska, A.; Czerny, B.; Hryniewicz, K.; Ferland, G. J.

    2016-11-01

    We show that the recently observed suppression of the gap between the broad-line region (BLR) and the narrow-line region (NLR) in some active galactic nuclei (AGNs) can be fully explained by an increase of the gas density in the emitting region. Our model predicts the formation of the intermediate-line region (ILR) that is observed in some Seyfert galaxies by the detection of emission lines with intermediate-velocity FWHM ∼ 700–1200 km s‑1. These lines are believed to be originating from an ILR located somewhere between the BLR and NLR. As was previously proved, the apparent gap is assumed to be caused by the presence of dust beyond the sublimation radius. Our computations with the use of the cloudy photoionization code show that the differences in the shape of the spectral energy distribution from the central region of AGNs do not diminish the apparent gap in the line emission in those objects. A strong discontinuity in the line emission versus radius exists for all lines at the dust sublimation radius. However, increasing the gas density to ∼{10}11.5 cm‑3 at the sublimation radius provides the continuous line emission versus radius and fully explains the recently observed lack of apparent gap in some AGNs. We show that such a high density is consistent with the density of upper layers of an accretion disk atmosphere. Therefore, the upper layers of the disk atmosphere can give rise to the formation of observed emission-line clouds.

  1. Resistive wall mode active control physics design for KSTAR

    NASA Astrophysics Data System (ADS)

    Park, Y. S.; Sabbagh, S. A.; Bak, J. G.; Bialek, J. M.; Berkery, J. W.; Lee, S. G.; Oh, Y. K.

    2014-01-01

    As KSTAR H-mode operation approaches the region where the resistive wall mode (RWM) can be unstable, an important issue for future long pulse, high beta plasma operation is to evaluate RWM active feedback control performance using a planned active/passive RWM stabilization system on the device. In particular, an optimal design of feedback sensors allows mode stabilization up to the highest achievable βN close to the ideal with-wall limit, βNwall, with reduced control power requirements. The computed ideal n = 1 mode structure from the DCON code has been input to the VALEN-3D code to calculate the projected performance of an active RWM control system in the KSTAR three-dimensional conducting structure device geometry. Control performance with the midplane locked mode detection sensors, off-midplane saddle loops, and magnetic pickup coils is examined. The midplane sensors measuring the radial component of the mode perturbation is found to be strongly affected by the wall eddy current. The off-axis saddle loops with proper compensation of the prompt applied field are computed to provide stabilization at βN up to 86% of βNwall but the low RWM amplitude computed in the off-axis regions near the sensors can produce a low signal-to-noise ratio. The required control power and bandwidth are also estimated with varied noise levels in the feedback sensors. Further improvements have been explored by examining a new RWM sensor design motivated by the off-midplane poloidal magnetic field sensors in NSTX. The new sensors mounted off of the copper passive stabilizer plates near the device midplane show a clear advantage in control performance corresponding to achieving 99% of βNwall without the need of compensation of the prompt field. The result shows a significant improvement of RWM feedback stabilization using the new sensor set which motivates a future feedback sensor upgrade.

  2. A Conceptual Design of a Short Takeoff and Landing Regional Jet Airliner

    NASA Technical Reports Server (NTRS)

    Hahn, Andrew S.

    2010-01-01

    Most jet airliner conceptual designs adhere to conventional takeoff and landing performance. Given this predominance, takeoff and landing performance has not been critical, since it has not been an active constraint in the design. Given that the demand for air travel is projected to increase dramatically, there is interest in operational concepts, such as Metroplex operations that seek to unload the major hub airports by using underutilized surrounding regional airports, as well as using underutilized runways at the major hub airports. Both of these operations require shorter takeoff and landing performance than is currently available for airliners of approximately 100-passenger capacity. This study examines the issues of modeling performance in this now critical flight regime as well as the impact of progressively reducing takeoff and landing field length requirements on the aircraft s characteristics.

  3. Active region upflows. II. Data driven magnetohydrodynamic modelling

    NASA Astrophysics Data System (ADS)

    Galsgaard, K.; Madjarska, M. S.; Vanninathan, K.; Huang, Z.; Presmann, M.

    2015-12-01

    Context. Observations of many active regions show a slow systematic outflow/upflow from their edges lasting from hours to days. At present no physical explanation has been proven, while several suggestions have been put forward. Aims: This paper investigates one possible method for maintaining these upflows assuming, that convective motions drive the magnetic field to initiate them through magnetic reconnection. Methods: We use Helioseismic and Magnetic Imager (HMI) data to provide an initial potential 3D magnetic field of the active region NOAA 11123 on 2010 November 13 where the characteristic upflow velocities are observed. A simple 1D hydrostatic atmospheric model covering the region from the photosphere to the corona is derived. Local correlation tracking of the magnetic features in the HMI data is used to derive a proxy for the time dependent velocity field. The time dependent evolution of the system is solved using a resistive 3D magnetohydrodynamic code. Results: The magnetic field contains several null points located well above the photosphere, with their fan planes dividing the magnetic field into independent open and closed flux domains. The stressing of the interfaces between the different flux domains is expected to provide locations where magnetic reconnection can take place and drive systematic flows. In this case, the region between the closed and open flux is identified as the region where observations find the systematic upflows. Conclusions: In the present experiment, the driving only initiates magneto-acoustic waves without driving any systematic upflows at any of the flux interfaces. Movie is available in electronic form at http://www.aanda.org

  4. Magnet designs for muon collider ring and interactions regions

    SciTech Connect

    Zlobin, A.V.; Alexahin, Y.I.; Kashikhin, V.V.; Mokhov, N.V.; /Fermilab

    2010-05-01

    Conceptual designs of superconducting magnets for the storage ring of a Muon Collider with a 1.5 TeV c.o.m. energy and an average luminosity of 10{sup 34} cm{sup -2}s{sup -1} are presented. All magnets are based on Nb{sub 3}Sn superconductor and designed to provide an adequate operating field/field gradient in the aperture with the critical current margin required for reliable magnet operation in the machine. Magnet cross-sections were optimized to achieve the accelerator field quality in the magnet aperture occupied with beams. The magnets and corresponding protective measures are designed to handle about 0.5 kW/m of dynamic heat load from the muon beam decays. Magnet parameters are reported and compared with the requirements.

  5. On the Periodicity of Energy Release in Solar Active Regions

    NASA Astrophysics Data System (ADS)

    Goldvarg, T. B.; Nagovitsyn, Yu. A.; Solov'Ev, A. A.

    2005-06-01

    We investigate the periodic regimes of energy release on the Sun, namely, the recurrence of solar flares in active regions using the Solar Geophysical Data Journal on Hα flares from 1979 until 1981, which corresponds to the maximum of solar cycle 21. We obtained the following series of periods in the manifestation of flare activity bymeans of a correlation periodogram analysis, a self-similarity function, and a wavelet analysis: ˜1, 2, 3 h as well as ˜0.4, 1, 2, 5 days. We suggest a diffusive model for the quasi-periodic transfer of toroidal magnetic fields from under the photosphere to interpret the retrieved sequence of periods in the enhancement of flare activity. We estimated the typical spatial scales of the magnetic field variations in the solar convection zone: ˜17 000 km.

  6. 14 CFR 25.1181 - Designated fire zones; regions included.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... combustion equipment installation described in § 25.859; (6) The compressor and accessory sections of turbine engines; and (7) Combustor, turbine, and tailpipe sections of turbine engine installations that contain lines or components carrying flammable fluids or gases. (b) Each designated fire zone must meet...

  7. 14 CFR 29.1181 - Designated fire zones: regions included.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) The compressor and accessory sections of turbine engines; and (7) The combustor, turbine, and tailpipe sections of turbine engine installations except sections that do not contain lines and components carrying flammable fluids or gases and are isolated from the designated fire zone prescribed in paragraph (a)(6)...

  8. Monitoring rice farming activities in the Mekong Delta region

    NASA Astrophysics Data System (ADS)

    Nguyen, S. T.; Chen, C. F.; Chen, C. R.; Chiang, S. H.; Chang, L. Y.; Khin, L. V.

    2015-12-01

    Half of the world's population depends on rice for survival. Rice agriculture thus plays an important role in the developing world's economy. Vietnam is one of the largest rice producers and suppliers on earth and more than 80% of the exported rice was produced from the Mekong Delta region, which is situated in the southwestern Vietnam and encompasses approximately 40,000 km2. Changes in climate conditions could likely trigger the increase of insect populations and rice diseases, causing the potential loss of rice yields. Monitoring rice-farming activities through crop phenology detection can provide policymakers with timely strategies to mitigate possible impacts on the potential yield as well as rice grain exports to ensure food security for the region. The main objective of this study is to develop a logistic-based algorithm to investigate rice sowing and harvesting activities from the multi-temporal Moderate Resolution Imaging Spectroradiometer (MODIS)-Landsat fusion data. We processed the data for two main cropping seasons (i.e., winter-spring and summer-autumn seasons) through a three-step procedure: (1) MODIS-Landsat data fusion, (2) construction of the time-series enhanced vegetation index 2 (EVI2) data, (3) rice crop phenology detection. The EVI2 data derived from the fusion results between MODIS and Landsat data were compared with that of Landsat data indicated close correlation between the two datasets (R2 = 0.93). The time-series EVI2 data were processed using the double logistic method to detect the progress of sowing and harvesting activities in the region. The comparisons between the estimated sowing and harvesting dates and the field survey data revealed the root mean squared error (RMSE) values of 8.4 and 5.5 days for the winter-spring crop and 9.4 and 12.8 days for the summer-autumn crop, respectively. This study demonstrates the effectiveness of the double logistic-based algorithm for rice crop monitoring from temporal MODIS-Landsat fusion data

  9. FORMATION OF CORONAL HOLES ON THE ASHES OF ACTIVE REGIONS

    SciTech Connect

    Karachik, Nina V.; Pevtsov, Alexei A.; Abramenko, Valentyna I. E-mail: apevtsov@nso.ed

    2010-05-10

    We investigate the formation of isolated non-polar coronal holes (CHs) on the remnants of decaying active regions (ARs) at the minimum/early ascending phase of sunspot activity. We follow the evolution of four bipolar ARs and measure several parameters of their magnetic fields including total flux, imbalance, and compactness. As regions decay, their leading and following polarities exhibit different dissipation rates: loose polarity tends to dissipate faster than compact polarity. As a consequence, we see a gradual increase in flux imbalance inside a dissipating bipolar region, and later a formation of a CH in place of more compact magnetic flux. Out of four cases studied in detail, two CHs had formed at the following polarity of the decaying bipolar AR, and two CHs had developed in place of the leading polarity field. All four CHs contain a significant fraction of magnetic field of their corresponding AR. Using potential field extrapolation, we show that the magnetic field lines of these CHs were closed on the polar CH at the North, which at the time of the events was in imbalance with the polar CH at the South. This topology suggests that the observed phenomenon may play an important role in transformation of toroidal magnetic field to poloidal field, which is a key step in transitioning from an old solar cycle to a new one. The timing of this observed transition may indicate the end of solar cycle 23 and the beginning of cycle 24.

  10. Helioseismology of pre-emerging active regions. III. Statistical analysis

    SciTech Connect

    Barnes, G.; Leka, K. D.; Braun, D. C.; Birch, A. C.

    2014-05-01

    The subsurface properties of active regions (ARs) prior to their appearance at the solar surface may shed light on the process of AR formation. Helioseismic holography has been applied to samples taken from two populations of regions on the Sun (pre-emergence and without emergence), each sample having over 100 members, that were selected to minimize systematic bias, as described in Paper I. Paper II showed that there are statistically significant signatures in the average helioseismic properties that precede the formation of an AR. This paper describes a more detailed analysis of the samples of pre-emergence regions and regions without emergence based on discriminant analysis. The property that is best able to distinguish the populations is found to be the surface magnetic field, even a day before the emergence time. However, after accounting for the correlations between the surface field and the quantities derived from helioseismology, there is still evidence of a helioseismic precursor to AR emergence that is present for at least a day prior to emergence, although the analysis presented cannot definitively determine the subsurface properties prior to emergence due to the small sample sizes.

  11. Preliminary design activities for solar heating and cooling systems

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Information on the development of solar heating and cooling systems is presented. The major emphasis is placed on program organization, system size definition, site identification, system approaches, heat pump and equipment design, collector procurement, and other preliminary design activities.

  12. Active tectonics and earthquake potential of the Myanmar region

    NASA Astrophysics Data System (ADS)

    Wang, Yu; Sieh, Kerry; Tun, Soe Thura; Lai, Kuang-Yin; Myint, Than

    2014-04-01

    This paper describes geomorphologic evidence for the principal neotectonic features of Myanmar and its immediate surroundings. We combine this evidence with published structural, geodetic, and seismic data to present an overview of the active tectonic architecture of the region and its seismic potential. Three tectonic systems accommodate oblique collision of the Indian plate with Southeast Asia and extrusion of Asian territory around the eastern syntaxis of the Himalayan mountain range. Subduction and collision associated with the Sunda megathrust beneath and within the Indoburman range and Naga Hills accommodate most of the shortening across the transpressional plate boundary. The Sagaing fault system is the predominant locus of dextral motion associated with the northward translation of India. Left-lateral faults of the northern Shan Plateau, northern Laos, Thailand, and southern China facilitate extrusion of rocks around the eastern syntaxis of the Himalaya. All of these systems have produced major earthquakes within recorded history and continue to present major seismic hazards in the region.

  13. Time Dependence of Joy's Law for Emerging Active Regions

    NASA Astrophysics Data System (ADS)

    Chintzoglou, Georgios; Zhang, J.; Liu, Y.

    2013-07-01

    Joy's law governs the tilt of Active Regions (ARs) with respect to their absolute heliographic latitude. Together with Hale's law of hemispheric polarity, it is essential in constraining solar dynamo models. However, previous studies on Joy's law show only a weak positive trend between AR tilt angles and latitudes. In this study, we are focusing on the time dependence of Joy's law, for the cases of emerging ARs of Solar Cycle 24. We selected 40 ARs that emerge on the East hemisphere, effectively maximizing the observing time for each AR. Then, by converting the helioprojective maps into heliographic, we determine the geometrical as well as the magnetic-flux-weighted centroids for each emergence case. That way we are able to track the temporal evolution of their physical properties, including locations, fluxes of positive and negative polarities, as well as the tilt angles of these regions in a continuous manner until emergence stops and the ARs assume their final state.

  14. Multi-wavelength Observations of Solar Active Region NOAA 7154

    NASA Technical Reports Server (NTRS)

    Bruner, M. E.; Nitta, N. V.; Frank. Z. A.; Dame, L.; Suematsu, Y.

    2000-01-01

    We report on observations of a solar active region in May 1992 by the Solar Plasma Diagnostic Experiment (SPDE) in coordination with the Yohkoh satellite (producing soft X-ray images) and ground-based observatories (producing photospheric magnetograms and various filtergrams including those at the CN 3883 A line). The main focus is a study of the physical conditions of hot (T is approximately greater than 3 MK) coronal loops at their foot-points. The coronal part of the loops is fuzzy but what appear to be their footpoints in the transition region down to the photosphere are compact. Despite the morphological similarities, the footpoint emission at 10(exp 5) K is not quantitatively correlated with that at approximately 300 km above the tau (sub 5000) = 1 level, suggesting that the heat transport and therefore magnetic field topology in the intermediate layer is complicated. High resolution imaging observations with continuous temperature coverage are crucially needed.

  15. Atomic hydrogen maser active oscillator cavity and bulb design optimization

    NASA Technical Reports Server (NTRS)

    Peters, H. E.; Washburn, P. J.

    1984-01-01

    The performance characteristics and reliability of the active oscillator atomic hydrogen maser depend upon oscillation parameters which characterize the interaction region of the maser, the resonant cavity and atom storage bulb assembly. With particular attention to use of the cavity frequency switching servo (1) to reduce cavity pulling, it is important to maintain high oscillation level, high atomic beam flux utilization efficiency, small spin exchange parameter and high cavity quality factor. It is also desirable to have a small and rigid cavity and bulb structure and to minimize the cavity temperature sensitivity. Curves for a novel hydrogen maser cavity configuration which is partially loaded with a quartz dielectric cylinder and show the relationships between cavity length, cavity diameter, bulb size, dielectric thickness, cavity quality factor, filling factor and cavity frequency temperature coefficient are presented. The results are discussed in terms of improvement in maser performance resulting from particular design choices.

  16. Influence of the Cardiac Myosin Hinge Region on Contractile Activity

    NASA Astrophysics Data System (ADS)

    Margossian, Sarkis S.; Krueger, John W.; Sellers, James R.; Cuda, Giovanni; Caulfield, James B.; Norton, Paul; Slayter, Henry S.

    1991-06-01

    The participation of cardiac myosin hinge in contractility was investigated by in vitro motility and ATPase assays and by measurements of sarcomere shortening. The effect on contractile activity was analyzed using an antibody directed against a 20-amino acid peptide within the hinge region of myosin. This antibody bound specifically at the hinge at a distance of 55 nm from the S1/S2 junction, was specific to human, dog, and rat cardiac myosins, did not crossreact with gizzard or skeletal myosin, and had no effect on ATPase activity of purified S1 and myofibrils. However, it completely suppressed the movement of actin filaments in in vitro motility assays and reduced active shortening of sarcomeres of skinned cardiac myocytes by half. Suppression of motion by the antihinge antibody may reflect a mechanical constraint imposed by the antibody upon the mobility of the S2 region of myosin. The results suggest that the steps in the mechanochemical energy transduction can be separately influenced through S2.

  17. Influence of the cardiac myosin hinge region on contractile activity.

    PubMed

    Margossian, S S; Krueger, J W; Sellers, J R; Cuda, G; Caulfield, J B; Norton, P; Slayter, H S

    1991-06-01

    The participation of cardiac myosin hinge in contractility was investigated by in vitro motility and ATPase assays and by measurements of sarcomere shortening. The effect on contractile activity was analyzed using an antibody directed against a 20-amino acid peptide within the hinge region of myosin. This antibody bound specifically at the hinge at a distance of 55 nm from the S1/S2 junction, was specific to human, dog, and rat cardiac myosins, did not crossreact with gizzard or skeletal myosin, and had no effect on ATPase activity of purified S1 and myofibrils. However, it completely suppressed the movement of actin filaments in in vitro motility assays and reduced active shortening of sarcomeres of skinned cardiac myocytes by half. Suppression of motion by the anti-hinge antibody may reflect a mechanical constraint imposed by the antibody upon the mobility of the S2 region of myosin. The results suggest that the steps in the mechanochemical energy transduction can be separately influenced through S2.

  18. An RC active filter design handbook

    NASA Technical Reports Server (NTRS)

    Deboo, G. J.

    1977-01-01

    The design of filters is described. Emphasis is placed on simplified procedures that can be used by the reader who has minimum knowledge about circuit design and little acquaintance with filter theory. The handbook has three main parts. The first part is a review of some information that is essential for work with filters. The second part includes design information for specific types of filter circuitry and describes simple procedures for obtaining the component values for a filter that will have a desired set of characteristics. Pertinent information relating to actual performance is given. The third part (appendix) is a review of certain topics in filter theory and is intended to provide some basic understanding of how filters are designed.

  19. High Spatial Resolution Fe XII Observations of Solar Active Regions

    NASA Astrophysics Data System (ADS)

    Testa, Paola; De Pontieu, Bart; Hansteen, Viggo

    2016-08-01

    We use UV spectral observations of active regions with the Interface Region Imaging Spectrograph (IRIS) to investigate the properties of the coronal Fe xii 1349.4 Å emission at unprecedented high spatial resolution (˜0.33″). We find that by using appropriate observational strategies (i.e., long exposures, lossless compression), Fe xii emission can be studied with IRIS at high spatial and spectral resolution, at least for high-density plasma (e.g., post-flare loops and active region moss). We find that upper transition region (TR; moss) Fe xii emission shows very small average Doppler redshifts ({v}{{D}} ˜ 3 km s‑1) as well as modest non-thermal velocities (with an average of ˜24 km s‑1 and the peak of the distribution at ˜15 km s‑1). The observed distribution of Doppler shifts appears to be compatible with advanced three-dimensional radiative MHD simulations in which impulsive heating is concentrated at the TR footpoints of a hot corona. While the non-thermal broadening of Fe xii 1349.4 Å peaks at similar values as lower resolution simultaneous Hinode Extreme Ultraviolet Imaging Spectrometer (EIS) measurements of Fe xii 195 Å, IRIS observations show a previously undetected tail of increased non-thermal broadening that might be suggestive of the presence of subarcsecond heating events. We find that IRIS and EIS non-thermal line broadening measurements are affected by instrumental effects that can only be removed through careful analysis. Our results also reveal an unexplained discrepancy between observed 195.1/1349.4 Å Fe xii intensity ratios and those predicted by the CHIANTI atomic database.

  20. Ancient Tectonic and Volcanic Activity in the Tharsis Region

    NASA Astrophysics Data System (ADS)

    Werner, S. C.; Kronberg, P.; Hauber, E.; Grott, M.; Steinberger, B.; Torsvik, T. H.; Neukum, G.

    The two topographically dominating volcanic provinces on Mars are the Tharsis and the Elysium regions, situated close to the equator on the dichotomy boundary between the heavily cratered (older) highlands and the northern lowlands (about 100 degrees apart). The regions are characterized by volcanoes whose morphologies are analogous to volcanic landforms on Earth, and the huge volcanoes in the Tharsis region (Olympus Mons and Tharsis Montes) are prime examples resembling many characteristics of Hawaiian shield volcanoes. The main difference between the Martian and terrestrial volcanoes are their size and the length of the flows, possibly due to higher eruption rates, the "stationary" character of the source (no plate tectonics) and the lower gravity. The Tharsis plateau is the topographically most prominent region on Mars, and associated with an areoid high. On Earth, large geoid highs are related to longlived heterogeneities near the core-mantle boundary that are sources for large igneous provinces. The Tharsis' volcanic vent structures were active at least episodically over the past 4 billion years (based on crater count statistics), which indicates long-lived volcanic and magmatic activity. Two major groups of tectonic features are related to the Tharsis bulge: a concentric set of wrinkle ridges indicating compression radial to Tharsis,and several sets of extensional structures that radiate outward from different centers within Tharsis, indicating tension circumferential to Tharsis. No landforms imply ancient plate tectonics. Here, we present surface ages associated with volcanic and tectonic landforms with a special focus on the ancient magma-tectonic environment (see Grott et al. 2006, this volume). We will examine the long-lived volcanism and tectonic surface expressions and discuss whether Mars volcanism could represent deep mantle plumes.

  1. High Spatial Resolution Fe XII Observations of Solar Active Regions

    NASA Astrophysics Data System (ADS)

    Testa, Paola; De Pontieu, Bart; Hansteen, Viggo

    2016-08-01

    We use UV spectral observations of active regions with the Interface Region Imaging Spectrograph (IRIS) to investigate the properties of the coronal Fe xii 1349.4 Å emission at unprecedented high spatial resolution (˜0.33″). We find that by using appropriate observational strategies (i.e., long exposures, lossless compression), Fe xii emission can be studied with IRIS at high spatial and spectral resolution, at least for high-density plasma (e.g., post-flare loops and active region moss). We find that upper transition region (TR; moss) Fe xii emission shows very small average Doppler redshifts ({v}{{D}} ˜ 3 km s-1) as well as modest non-thermal velocities (with an average of ˜24 km s-1 and the peak of the distribution at ˜15 km s-1). The observed distribution of Doppler shifts appears to be compatible with advanced three-dimensional radiative MHD simulations in which impulsive heating is concentrated at the TR footpoints of a hot corona. While the non-thermal broadening of Fe xii 1349.4 Å peaks at similar values as lower resolution simultaneous Hinode Extreme Ultraviolet Imaging Spectrometer (EIS) measurements of Fe xii 195 Å, IRIS observations show a previously undetected tail of increased non-thermal broadening that might be suggestive of the presence of subarcsecond heating events. We find that IRIS and EIS non-thermal line broadening measurements are affected by instrumental effects that can only be removed through careful analysis. Our results also reveal an unexplained discrepancy between observed 195.1/1349.4 Å Fe xii intensity ratios and those predicted by the CHIANTI atomic database.

  2. From snakes to region-based active contours defined by region-dependent parameters.

    PubMed

    Jehan-Besson, Stéphanie; Gastaud, Muriel; Precioso, Frédéric; Barlaud, Michel; Aubert, Gilles; Debreuve, Eric

    2004-01-10

    Image and sequence segmentation of a the segmentation task are discussed from the point of view of optimizing the segmentation criterion. Such a segmentation criterion involves so-called (boundary and region) descriptors, which, in general, may depend on their respective boundaries or regions. This dependency must be taken into account when one is computing the criterion derivative with respect to the unknown object domain (defined by its boundary). If this dependency not considered, some correctional terms may be omitted. Computing the derivative of the segmentation criterion with a dynamic scheme is described. The scheme is general enough to provide a framework for a wide variety of applications in segmentation. It also provides a theoretical meaning to the philosophy of active contours.

  3. The coronal and transition region temperature structure of a solar active region

    NASA Technical Reports Server (NTRS)

    Levine, R. H.; Pye, J. P.

    1980-01-01

    Using measurements of EUV and X-ray spectral lines, the differential emission measure vs electron temperature from the transition region to the corona of an active region (electron temperature between 100,000 and 5,000,000 K) is derived. The total emission measure and radiative losses are of the order 3 x 10 to the 48th/cu cm and 4 x 10 to the 26th ergs/sec, respectively. The emission measure at electron temperatures greater than approximately 1,000,000 K (i.e. that mainly responsible for the X-ray emission) is about 75% of the total. The use of the Mg x line at 625 A as an indicator of coronal electron density is also examined. A set of theoretical energy balance models of coronal loops in which the loop divergence is a variable parameter is presented and compared with the observations.

  4. Implications of Special Regions to Conducting Human Activities on Mars

    NASA Astrophysics Data System (ADS)

    Rummel, J. D.; Barlow, N. G.; Beaty, D. W.; Jones, M. A.; Hipkin, V.

    2014-12-01

    A MEPAG Science Analysis Group (SAG) has undertaken an analysis of Special Regions (SR) on Mars—regions where indigenous martian life could exist or where Earth microbes, if introduced, could survive and reproduce. The SR-SAG has considered the impact of SR on future human activities on the martian surface. Human exploration requires access to in-situ resources, some of which may be found in SR. Water and oxygen for ISRU are found in the atmosphere, surface/near-surface ice, hydrated minerals, and perchlorates. Water ice is most abundant at latitudes poleward of ~60 degrees, but polar darkness, cold temperatures, and CO2 degassing present hazards to human operations in these regions. Accessible water is more limited toward the equator, though temperature and solar energy conditions become more favorable. The possible presence of liquid water in Recurring Slope Lineae and active gullies leads to their treatment as SR. Fuel for surface operations and propellants for crew ascent could be manufactured from the martian atmosphere and surface materials, but dust in the atmosphere may clog ISRU equipment and perchlorate is toxic to humans. Power may be produced from solar or nuclear energy. Reliance on solar energy limits operations to the equatorial zone where easily accessible ice resources are limited. Nuclear power allows surface operations at a range of latitudes, but waste heat could convert some non-SR into SR. Radiation shielding is necessary for long-term human operations on Mars and could be obtained by deposition of regolith or by water storage in tanks or as ice around habitats, or the use of underground habitats. SR-SAG recognizes that it will be impossible for all human-associated processes and operations to be conducted within entirely closed systems. Protocols need to be established so (1) human missions to Mars will not contaminate SR nor be contaminated by materials from them, and (2) human activities on Mars will avoid converting areas into SR.

  5. Temporal evolution of continental lithospheric strength in actively deforming regions

    USGS Publications Warehouse

    Thatcher, W.; Pollitz, F.F.

    2008-01-01

    It has been agreed for nearly a century that a strong, load-bearing outer layer of earth is required to support mountain ranges, transmit stresses to deform active regions and store elastic strain to generate earthquakes. However the dept and extent of this strong layer remain controversial. Here we use a variety of observations to infer the distribution of lithospheric strength in the active western United States from seismic to steady-state time scales. We use evidence from post-seismic transient and earthquake cycle deformation reservoir loading glacio-isostatic adjustment, and lithosphere isostatic adjustment to large surface and subsurface loads. The nearly perfectly elastic behavior of Earth's crust and mantle at the time scale of seismic wave propagation evolves to that of a strong, elastic crust and weak, ductile upper mantle lithosphere at both earthquake cycle (EC, ???10?? to 103 yr) and glacio-isostatic adjustment (GIA, ???103 to 104 yr) time scales. Topography and gravity field correlations indicate that lithosphere isostatic adjustment (LIA) on ???106-107 yr time scales occurs with most lithospheric stress supported by an upper crust overlying a much weaker ductile subtrate. These comparisons suggest that the upper mantle lithosphere is weaker than the crust at all time scales longer than seismic. In contrast, the lower crust has a chameleon-like behavior, strong at EC and GIA time scales and weak for LIA and steady-state deformation processes. The lower crust might even take on a third identity in regions of rapid crustal extension or continental collision, where anomalously high temperatures may lead to large-scale ductile flow in a lower crustal layer that is locally weaker than the upper mantle. Modeling of lithospheric processes in active regions thus cannot use a one-size-fits-all prescription of rheological layering (relation between applied stress and deformation as a function of depth) but must be tailored to the time scale and tectonic

  6. THE EXPANSION OF ACTIVE REGIONS INTO THE EXTENDED SOLAR CORONA

    SciTech Connect

    Morgan, Huw; Jeska, Lauren; Leonard, Drew

    2013-06-01

    Advanced image processing of Large Angle and Spectrometric Coronagraph Experiment (LASCO) C2 observations reveals the expansion of the active region closed field into the extended corona. The nested closed-loop systems are large, with an apparent latitudinal extent of 50 Degree-Sign , and expanding to heights of at least 12 R{sub Sun }. The expansion speeds are {approx}10 km s{sup -1} in the AIA/SDO field of view, below {approx}20 km s{sup -1} at 2.3 R{sub Sun }, and accelerate linearly to {approx}60 km s{sup -1} at 5 R{sub Sun }. They appear with a frequency of one every {approx}3 hr over a time period of around three days. They are not coronal mass ejections (CMEs) since their gradual expansion is continuous and steady. They are also faint, with an upper limit of 3% of the brightness of background streamers. Extreme ultraviolet images reveal continuous birth and expansion of hot, bright loops from a new active region at the base of the system. The LASCO images show that the loops span a radial fan-like system of streamers, suggesting that they are not propagating within the main coronal streamer structure. The expanding loops brighten at low heights a few hours prior to a CME eruption, and the expansion process is temporarily halted as the closed field system is swept away. Closed magnetic structures from some active regions are not isolated from the extended corona and solar wind, but can expand to large heights in the form of quiescent expanding loops.

  7. Chromospheric Evolution and the Flare Activity of Super-Active Region NOAA 6555

    NASA Technical Reports Server (NTRS)

    PrasadC, Debi; Ambastha, Ashok; Srivastava, Nandita; Tripathy, Sushanta C.; Hagyard, Mona J.

    1997-01-01

    Super-active region NOAA 6555 was highly flare productive during the period March 21st - 27th, 1991 of its disk passage. We have studied its chromospheric activity using high spatial resolution H alpha filtergrams taken at Udaipur along with MSFC vector magnetograms. A possible relationship of flare productivity and the variation in shear has been explored. Flares were generally seen in those subareas of the active region which possessed closed magnetic field configuration, whereas only minor flares and/or surges occurred in subareas showing open magnetic field configuration. Physical mechanisms responsible for the observed surges are also discussed.

  8. Hinode Observations of an Eruption from a Sigmoidal Active Region

    NASA Astrophysics Data System (ADS)

    Green, L. M.; Wallace, A. J.; Kliem, B.

    2012-08-01

    We analyse the evolution of a bipolar active region which produces an eruption during its decay phase. The soft X-ray arcade develops high shear over a time span of two days and transitions to sigmoidal shortly before the eruption. We propose that the continuous sigmoidal soft X-ray threads indicate that a flux rope has formed which is lying low in the solar atmosphere with a bald patch separatrix surface topology. The formation of the flux rope is driven by the photospheric evolution which is dominated by fragmentation of the main polarities, motion due to supergranular flows and cancellation at the polarity inversion line.

  9. SOI/MDI studies of active region seismology and evolution

    NASA Technical Reports Server (NTRS)

    Tarbell, Ted D.; Title, Alan; Hoeksema, J. Todd; Scherrer, Phil; Zweibel, Ellen

    1995-01-01

    The solar oscillations investigation (SOI) will study solar active regions using both helioseismic and conventional observation techniques. The Michelson Doppler imager (MDI) can perform Doppler continuum and line depth imagery and can produce longitudinal magnetograms, showing either the full disk or a high resolution field of view. A dynamics program of continuous full disk Doppler observations for two months per year, campaign programs of eight hours of continuous observation per day, and a synoptic magnetic program of about 15 full disk magnetograms per day, are planned. The scientific plans, measurements and observation programs, are described.

  10. The distribution of maximum temperatures of coronal active region loops

    NASA Technical Reports Server (NTRS)

    Teske, R. G.; Mayfield, E. B.

    1981-01-01

    Starting with the integrated emission measure distributions of solar active regions, the distribution of the maximum temperature parameter which characterizes individual plasma loops is determined. The observed emission measure distributions were determined by combining EUV and X-ray data from two separate experiments on ATM/Skylab. The present work sets some limits on such an approach. It is found that the distribution of maximum temperature has approximately the same shape as the integrated emission measure distributions, a result which is expected since most of the loop emission measure is near their maximum temperatures.

  11. Emission Measure Distribution and Heating of Two Active Region Cores

    NASA Technical Reports Server (NTRS)

    Tripathi, Durgesh; Klimchuk, James A.; Mason, Helen E.

    2011-01-01

    Using data from the Extreme-ultraviolet Imaging Spectrometer aboard Hinode, we have studied the coronal plasma in the core of two active regions. Concentrating on the area between opposite polarity moss, we found emission measure distributions having an approximate power-law form EM/T(exp 2.4) from log T = 5.55 up to a peak at log T = 6.57. The observations are explained extremely well by a simple nanoflare model. However, in the absence of additional constraints, the observations could possibly also be explained by steady heating.

  12. Rational Design of Coumarin Derivatives as CK2 Inhibitors by Improving the Interaction with the Hinge Region.

    PubMed

    Zhang, Na; Chen, Wen-Juan; Zhou, Yue; Zhao, Hongtao; Zhong, Ru-Gang

    2016-01-01

    Design of novel coumarin derivatives as CK2 inhibitors were attempted by targeting the interaction with the hinge region. A set of substituents capable of forming a hydrogen bond or halogen bond with the hinge region were screened in silico, and trifluoromethyl emerges as a promising motif by forming favorable electrostatic interaction and a presumable halogen bond with the hinge region. As proof of concept, three trifluoromethyl derivatives of coumarin were synthesized and tested in vitro. The results indicated that replacement of methyl by trifluoromethyl leads to a modest 5-fold improvement in potency, with the most active compound being 0.4 µM. The newly designed compounds were further screened on one lung cancer cell line A549, showing low micromolar anti-proliferative activity.

  13. Implications of Regional Transmission Organization Design for Renewable Energy Technologies

    SciTech Connect

    Porter, K.

    2002-05-01

    This report summarizes the development of Regional Transmission Organizations (RTOs) and assesses the potential implications of market rules for renewable energy technologies. The report focuses on scheduling provisions, as these have proved problematic in some cases for intermittent renewable energy technologies. Market rules of four RTOs-the Pennsylvania-Maryland-New Jersey ISO, the ERCOT ISO, the Midwest ISO and the New York ISO (NYISO)-were examined to determine the impact on intermittent renewable energy projects such as wind energy generators. Also, a more general look was taken at how biomass power may fare in RTOs, specifically whether these technologies can participate in ancillary service markets. Lastly, an assessment was made regarding the implications for renewable energy technologies of a Northeast-wide RTO that would combine the three existing Northeast ISOs (the aforementioned PJM and NYISOs, as well as ISO New England).

  14. Peptides of the Constant Region of Antibodies Display Fungicidal Activity

    PubMed Central

    Polonelli, Luciano; Ciociola, Tecla; Magliani, Walter; Zanello, Pier Paolo; D'Adda, Tiziana; Galati, Serena; De Bernardis, Flavia; Arancia, Silvia; Gabrielli, Elena; Pericolini, Eva; Vecchiarelli, Anna; Arruda, Denise C.; Pinto, Marcia R.; Travassos, Luiz R.; Pertinhez, Thelma A.; Spisni, Alberto; Conti, Stefania

    2012-01-01

    Synthetic peptides with sequences identical to fragments of the constant region of different classes (IgG, IgM, IgA) of antibodies (Fc-peptides) exerted a fungicidal activity in vitro against pathogenic yeasts, such as Candida albicans, Candida glabrata, Cryptococcus neoformans, and Malassezia furfur, including caspofungin and triazole resistant strains. Alanine-substituted derivatives of fungicidal Fc-peptides, tested to evaluate the critical role of each residue, displayed unaltered, increased or decreased candidacidal activity in vitro. An Fc-peptide, included in all human IgGs, displayed a therapeutic effect against experimental mucosal and systemic candidiasis in mouse models. It is intriguing to hypothesize that some Fc-peptides may influence the antifungal immune response and constitute the basis for devising new antifungal agents. PMID:22470523

  15. The morphology of flare phenomena, magnetic fields, and electric currents in active regions. II - NOAA active region 5747 (1989 October)

    NASA Technical Reports Server (NTRS)

    Leka, K. D.; Canfield, Richard C.; Mcclymont, A. N.; De La Beaujardiere, J.-F.; Fan, Yuhong; Tang, F.

    1993-01-01

    The paper describes October 1989 observations in NOAA Active Region 5747 of the morphology of energetic electron precipitation and high-pressure coronal flare plasmas of three flares and their relation to the vector magnetic field and vertical electric currents. The H-alpha spectroheliograms were coaligned with the vector magnetograms using continuum images of sunspots, enabling positional accuracy of a few arcsec. It was found that, during the gradual phase, the regions of the H-alpha flare that show the effects of enhanced pressure in the overlying corona often encompass extrema of the vertical current density, consistent with earlier work showing a close relationship between H-alpha emission and line-of-sight currents. The data are also consistent with the overall morphology and evolution described by erupting-filament models such as those of Kopp and Pneuman (1976) and Sturrock (1989).

  16. Active Region Magnetic Structure Observed in the Photosphere and Chromosphere

    NASA Technical Reports Server (NTRS)

    Leka, K. D.; Metcalf, Thomas R.

    2001-01-01

    The magnetic flux above sunspots and plage in NOAA (National Oceanic and Atmospheric Administration) Active Region 8299 has been measured in the photosphere and the chromosphere. We investigate the vertical magnetic structure above the umbrae, penumbrae and plage regions using quantitative statistical comparisons of the photospheric and chromospheric vector magnetic flux data. The results include: (1) a decrease in flux with height, (2) the direct detection of the superpenumbral canopy in the chromosphere, (3) values for dB/dz which are consistent with earlier investigations when derived from a straight difference between the two datasets but quite low when derived from the delta x B = 0 condition, (4) a monolithic structure in the umbra which extends well into the upper chromosphere with a very complex and varied structure in the penumbra and plage, as evidenced by (5) a uniform magnetic scale height in the umbrae with an abrupt jump to widely varying scale heights in the penumbral and plage regions. Further, we find (6) evidence for a very large (delta z approximately equals 3Mm) height difference between the atmospheric layers sampled in the two magnetograms, almost a factor of three larger than that implied by atmospheric models. We additionally test the apropriateness of using photospheric magnetic flux as a boundary for field-line extrapolations, and find a better agreement with observed coronal structure when the chromospheric flux is used as a boundary.

  17. Plasma Beta Above a Solar Active Region: Rethinking the Paradigm

    NASA Technical Reports Server (NTRS)

    Gary, G. Allen; Whitaker, Ann F. (Technical Monitor)

    2001-01-01

    In this paper, we present a model of the plasma beta above an active region and discuss its consequences in terms of coronal magnetic field modeling. The beta-plasma model is representative and derived from a collection of sources. The resulting beta variation with height is used to emphasize the assumption that the magnetic pressure dominates over the plasma pressure must be carefully considered depending on what part of the solar atmosphere is being considered. This paper points out (1) that the paradigm that the coronal magnetic field can be constructed from a force-free magnetic field must be used in the correct context, since the forcefree region is sandwiched between two regions which have beta greater than 1, (2) that the chromospheric MgIICIV magnetic measurements occur near the beta-minimum, and (3) that, moving from the photosphere upwards, beta can return to 1 at relatively low coronal heights, e.g. R approximately 1.2R(sub)s.

  18. Magnetic helicity and free energy in solar active regions

    NASA Astrophysics Data System (ADS)

    Moraitis, K.; Georgoulis, M.; Tziotziou, K.; Archontis, V.

    2013-09-01

    We study the evolution of the non-potential free magnetic energy and relative magnetic helicity budgets in solar active regions (ARs). For this we use a time-series of a three-dimensional, synthetic AR produced by magnetohydrodynamical (MHD) simulations. As a first step, we calculate the potential magnetic field that has the same normal components with the MHD field along all boundaries of the AR, by solving Laplace's equation. The free magnetic energy of the AR is then easily derived. From the two fields, MHD and potential one, we calculate the corresponding vector potentials with a recently proposed integration method. The knowledge of both fields and their respective vector potentials throughout the AR, allows us to estimate the relative magnetic helicity budget of the AR. Following this procedure for each snapshot of the AR, we reconstruct the evolution of free energy and helicity in the AR. Our method reproduces, for a synthetic AR, the energy/helicity relations known to hold in real active regions.

  19. Multi-Wavelength Study of Active Region Loop Dynamics

    NASA Astrophysics Data System (ADS)

    Banerjee, D.

    2006-11-01

    Observations have revealed the existence of weak transient disturbances in extended coronal loop systems. These propagating disturbances (PDs) originate from small scale brightenings at the footpoints of the loops and propagate upward along the loops. In all cases observed, the projected propagation speed is close to, but below the expected sound speed in the loops. This suggests that the PDs could be interpreted as slow mode MHD waves. Interpreting the oscillation in terms of different wave modes and/or plasma motions always depend on the line of sight as we observe in the limb or on the center of the disk. The JOP 165 campaign will address some of these questions. MDI and TRACE photospheric and UV imaging of TRACE and SPIRIT have been acquired simultaneously with high temporal and spatial coverage along with the spectroscopic data from CDS. EIT was operated in the shutter-less mode to achieve high Cadence. Some of the off- limb active region dynamics and oscillations observed during this JOP campaign will be focused in this presentation. Plasma condensations and temporal variations in active region loops will be also addressed.

  20. Magnetic field measurements in and above a limb active region

    NASA Astrophysics Data System (ADS)

    Philip, Judge

    2013-07-01

    We analyze spectropolarimetric data of a limb active region (NOAA 11302) obtained on September 22nd 2011 using the Facility Infrared Spectrometer (FIRS) at the Dunn Solar Telescope (DST). Stokes profiles including lines of Si I 1028.7 nm and He I 1083 nm were obtained in three scans over a 45"x75" area. Simultaneous narrow band Ca II K and G-band intensity data were acquired with a cadence of 5s at the DST. The He I data show not only typical active region polarization signatures, but also signatures in plumes -- cool post flare loops -- which extend many Mm into the corona across the visible limb. The plumes have remarkably uniform brightness, and the plume plasma is significantly Doppler shifted as it drains from the corona. Using carefully constructed observing and calibration sequences and applying Principal Component Analysis to remove instrumental artifacts, we achieved a polarization sensitivity approaching 0.02%. With this sensitivity we attempt to diagnose the vector magnetic fields and plasma properties of chromospheric and cool coronal material in and above NOAA 11302. Inversions using various radiative transfer models in the HAZEL code are remarkably consistent with the idea that plume spectra are formed in a simple, slab-like geometry, but that the ``disk'' spectra are formed under more traditional models (Milne-Eddington). The inverted magnetic data of He I lines are compared with photospheric inversions of DST Si I and Fe I data from the Solar Dynamics Observatory.

  1. Active Region Filaments Might Harbor Weak Magnetic Fields

    NASA Astrophysics Data System (ADS)

    Díaz Baso, C. J.; Martínez González, M. J.; Asensio Ramos, A.

    2016-05-01

    Recent spectropolarimetric observations of active region filaments have revealed polarization profiles with signatures typical of the strong field Zeeman regime. The conspicuous absence in those observations of scattering polarization and Hanle effect signatures was then pointed out by some authors. This was interpreted as either a signature of mixed “turbulent” field components or as a result of optical thickness. In this article, we present a natural scenario to explain these Zeeman-only spectropolarimetric observations of active region (AR) filaments. We propose a two-component model, one on top of the other. Both components have horizontal fields, with the azimuth difference between them being close to 90°. The component that lies lower in the atmosphere is permeated by a strong field of the order of 600 G, while the upper component has much weaker fields, of the order of 10 G. The ensuing scattering polarization signatures of the individual components have opposite signs, so its combination along the line of sight reduces—and even can cancel out—the Hanle signatures, giving rise to an apparent Zeeman-only profile. This model is also applicable to other chromospheric structures seen in absorption above ARs.

  2. Designing Technology Activities that Teach Mathematics

    ERIC Educational Resources Information Center

    Silk, Eli M.; Higashi, Ross; Shoop, Robin; Schunn, Christian D.

    2010-01-01

    Over the past three years, the authors have conducted research in middle and high school classrooms in an effort to improve the effectiveness of robotics to teach science, technology, engineering, and mathematics (STEM) education--their focus has been on math. The authors have found that subtle changes in the design and setup of the lesson make a…

  3. Photospheric electric current and transition region brightness within an active region

    NASA Technical Reports Server (NTRS)

    Deloach, A. C.; Hagyard, M. J.; Rabin, D.; Moore, R. L.; Smith, B. J., Jr.; West, E. A.; Tandberg-Hanssen, E.

    1984-01-01

    Distributions of vertical electrical current density J(z) calculated from vector measurements of the photospheric magnetic field are compared with ultraviolet spectroheliograms to investigate whether resistive heating is an important source of enhanced emission in the transition region. The photospheric magnetic fields in Active Region 2372 were measured on April 6 and 7, 1980 with the Marshall Space Flight Center vector magnetograph; ultraviolet wavelength spectroheliograms (L-alpha and N V 1239 A) were obtained with the UV Spectrometer and Polarimeter experiment aboard the Solar Maximum Mission satellite. Spatial registration of the J(z) (5 arcsec resolution) and UV (3 arcsec resolution) maps indicates that the maximum current density is cospatial with a minor but persistent UV enhancement, but there is little detected current associated with other nearby bright areas. It is concluded that, although resistive heating may be important in the transition region, the currents responsible for the heating are largely unresolved in the present measurements and have no simple correlation with the residual current measured on 5-arcsec scales.

  4. Active Geodesics: Region-based Active Contour Segmentation with a Global Edge-based Constraint.

    PubMed

    Appia, Vikram; Yezzi, Anthony

    2011-11-01

    We present an active geodesic contour model in which we constrain the evolving active contour to be a geodesic with respect to a weighted edge-based energy through its entire evolution rather than just at its final state (as in the traditional geodesic active contour models). Since the contour is always a geodesic throughout the evolution, we automatically get local optimality with respect to an edge fitting criterion. This enables us to construct a purely region-based energy minimization model without having to devise arbitrary weights in the combination of our energy function to balance edge-based terms with the region-based terms. We show that this novel approach of combining edge information as the geodesic constraint in optimizing a purely region-based energy yields a new class of active contours which exhibit both local and global behaviors that are naturally responsive to intuitive types of user interaction. We also show the relationship of this new class of globally constrained active contours with traditional minimal path methods, which seek global minimizers of purely edge-based energies without incorporating region-based criteria. Finally, we present some numerical examples to illustrate the benefits of this approach over traditional active contour models.

  5. Characteristics, location and origin of flare activity in a complex active region

    NASA Technical Reports Server (NTRS)

    Machado, M. E.; Gary, G. A.; Hagyard, M. J.; Hernandez, A. M.; Rovira, M. G.

    1986-01-01

    The observational characteristics of series of multiple-loop flares from a complex active region are summarized. The location of the highest observed photospheric magnetic shear is found to be the commonly observed site of flare onset, but not, in many cases, the magnetic region where the largest time-integrated energy release is observed. The observations thus reveal a consistent pattern of energy-release processes related to the magnetic-field topology.

  6. Teacher Educators' Design and Implementation of Group Learning Activities

    ERIC Educational Resources Information Center

    De Hei, Miranda S. A.; Sjoer, Ellen; Admiraal, Wilfried; Strijbos, Jan-Willem

    2016-01-01

    The aim of this study was to describe how teacher educators design and implement group learning activities (GLAs). We used the Group Learning Activities Instructional Design (GLAID) framework to analyse their descriptions. The GLAID framework includes eight components: (1) interaction, (2) learning objectives and outcomes, (3) assessment, (4) task…

  7. Repetitive Transcranial Magnetic Stimulation Activates Specific Regions in Rat Brain

    NASA Astrophysics Data System (ADS)

    Ji, Ru-Rong; Schlaepfer, Thomas E.; Aizenman, Carlos D.; Epstein, Charles M.; Qiu, Dike; Huang, Justin C.; Rupp, Fabio

    1998-12-01

    Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive technique to induce electric currents in the brain. Although rTMS is being evaluated as a possible alternative to electroconvulsive therapy for the treatment of refractory depression, little is known about the pattern of activation induced in the brain by rTMS. We have compared immediate early gene expression in rat brain after rTMS and electroconvulsive stimulation, a well-established animal model for electroconvulsive therapy. Our result shows that rTMS applied in conditions effective in animal models of depression induces different patterns of immediate-early gene expression than does electroconvulsive stimulation. In particular, rTMS evokes strong neural responses in the paraventricular nucleus of the thalamus (PVT) and in other regions involved in the regulation of circadian rhythms. The response in PVT is independent of the orientation of the stimulation probe relative to the head. Part of this response is likely because of direct activation, as repetitive magnetic stimulation also activates PVT neurons in brain slices.

  8. Extravehicular activities guidelines and design criteria

    NASA Technical Reports Server (NTRS)

    Brown, N. E.; Dashner, T. R.; Hayes, B. C.

    1973-01-01

    A listing of astronaut EVA support systems and equipment, and the physical, operational, and performance characteristics of each major system are presented. An overview of the major ground based support operations necessary in the development and verification of orbital EVA systems is included. The performance and biomedical characteristics of man in the orbital EV environment are discussed. Major factors affecting astronaut EV work performance are identified and delineated as they relate to EV support systems design. Data concerning the medical and physiological aspects of spaceflight on man are included. The document concludes with an extensive bibliography, and a series of appendices which expand on some of the information presented in the main body.

  9. Resistive wall mode active control physics design for KSTAR

    SciTech Connect

    Park, Y. S. Sabbagh, S. A.; Bialek, J. M.; Berkery, J. W.; Bak, J. G.; Lee, S. G.; Oh, Y. K.

    2014-01-15

    As KSTAR H-mode operation approaches the region where the resistive wall mode (RWM) can be unstable, an important issue for future long pulse, high beta plasma operation is to evaluate RWM active feedback control performance using a planned active/passive RWM stabilization system on the device. In particular, an optimal design of feedback sensors allows mode stabilization up to the highest achievable β{sub N} close to the ideal with-wall limit, β{sub N}{sup wall}, with reduced control power requirements. The computed ideal n = 1 mode structure from the DCON code has been input to the VALEN-3D code to calculate the projected performance of an active RWM control system in the KSTAR three-dimensional conducting structure device geometry. Control performance with the midplane locked mode detection sensors, off-midplane saddle loops, and magnetic pickup coils is examined. The midplane sensors measuring the radial component of the mode perturbation is found to be strongly affected by the wall eddy current. The off-axis saddle loops with proper compensation of the prompt applied field are computed to provide stabilization at β{sub N} up to 86% of β{sub N}{sup wall} but the low RWM amplitude computed in the off-axis regions near the sensors can produce a low signal-to-noise ratio. The required control power and bandwidth are also estimated with varied noise levels in the feedback sensors. Further improvements have been explored by examining a new RWM sensor design motivated by the off-midplane poloidal magnetic field sensors in NSTX. The new sensors mounted off of the copper passive stabilizer plates near the device midplane show a clear advantage in control performance corresponding to achieving 99% of β{sub N}{sup wall} without the need of compensation of the prompt field. The result shows a significant improvement of RWM feedback stabilization using the new sensor set which motivates a future feedback sensor upgrade.

  10. Comprehensive Design Reliability Activities for Aerospace Propulsion Systems

    NASA Technical Reports Server (NTRS)

    Christenson, R. L.; Whitley, M. R.; Knight, K. C.

    2000-01-01

    This technical publication describes the methodology, model, software tool, input data, and analysis result that support aerospace design reliability studies. The focus of these activities is on propulsion systems mechanical design reliability. The goal of these activities is to support design from a reliability perspective. Paralleling performance analyses in schedule and method, this requires the proper use of metrics in a validated reliability model useful for design, sensitivity, and trade studies. Design reliability analysis in this view is one of several critical design functions. A design reliability method is detailed and two example analyses are provided-one qualitative and the other quantitative. The use of aerospace and commercial data sources for quantification is discussed and sources listed. A tool that was developed to support both types of analyses is presented. Finally, special topics discussed include the development of design criteria, issues of reliability quantification, quality control, and reliability verification.

  11. Terahertz generation in mid-infrared quantum cascade lasers with a dual-upper-state active region

    SciTech Connect

    Fujita, Kazuue Hitaka, Masahiro; Ito, Akio; Edamura, Tadataka; Yamanishi, Masamichi; Jung, Seungyong; Belkin, Mikhail A.

    2015-06-22

    We report the performance of room temperature terahertz sources based on intracavity difference-frequency generation in mid-infrared quantum cascade lasers with a dual-upper-state (DAU) active region. DAU active region design is theoretically expected to produce larger optical nonlinearity for terahertz difference-frequency generation, compared to the active region designs of the bound-to-continuum type used previously. Fabricated buried heterostructure devices with a two-section buried distributed feedback grating and the waveguide designed for Cherenkov difference-frequency phase-matching scheme operate in two single-mode mid-infrared wavelengths at 10.7 μm and 9.7 μm and produce terahertz output at 2.9 THz with mid-infrared to terahertz conversion efficiency of 0.8 mW/W{sup 2} at room temperature.

  12. Comparison of Solar Active Region Complexity Andgeomagnetic Activity from 1996 TO 2014

    NASA Astrophysics Data System (ADS)

    Tanskanen, E. I.; Nikbakhsh, S.; Perez-Suarez, D.; Hackman, T.

    2015-12-01

    We have studied the influence of magnetic complexity of solar Active Regions (ARs)on geomagnetic activity from 1996 to 2014. Sunspots are visual indicators of ARswhere the solar magnetic field is disturbed. We have used International, American,Space Environment Service Center (SESC) and Space Weather Prediction Center(SWPC) sunspot numbers to examine ARs. Major manifestations of solar magneticactivity, such as flares and Coronal Mass Ejections (CMEs), are associated withARs. For this study we chose the Mount Wilson scheme. It classifies ARs in terms oftheir magnetic topology from the least complex (?) to the most complex one ( ?).Several cases have been found where the more complex structures produce strongerflares and CMEs than the less complex ones. We have a list of identified substormsavailable with different phases and their durations. This will be compared to ourmagnetic complexity data to analyse the effects of active region magnetic complexityto the magnetic activity on the vicinity of the Earth.

  13. Chromospheric magnetic fields of an active region filament

    NASA Astrophysics Data System (ADS)

    Xu, Z.; Solanki, S.; Lagg, A.

    2012-06-01

    Vector magnetic fields of an active region filament are co-spatially and co-temporally mapped in photosphere and upper chromosphere, by using spectro-polarimetric observations made by Tenerife Infrared Polarimeter (TIP II) at the German Vacuum Tower Telescope (VTT). A Zeeman-based ME inversion is performed on the full Stokes vectors of both the photospheric Si I 1082.7 nm and the chromospheric He I 1083.0 nm lines. We found that the strong magnetic fields, with the field strength of 600 - 800 G in the He I line formation height, are not uncommon among AR filaments. But such strong magnetic field is not always found in AR filaments.

  14. Investigating Molecular Hydrogen in Active Regions with IRIS

    NASA Astrophysics Data System (ADS)

    Jaeggli, Sarah A.; Saar, Steven H.; Daw, Adrian N.; Innes, Davina

    2014-06-01

    Molecular hydrogen should be the most abundant molecular species in sunspots, but recent observations with IRIS show that its florescent signature is absent from above the sunspot umbra, but appears brightly during flares. In this poster we continue the analysis of FUV observations of H2 in active regions, examining the correlation between the intensity of the H2 lines and the lines of C II and Si IV which are responsible for their excitation. We particularly focus on differentiating places where H2 is abundant, holes in the chromospheric opacity where FUV photons can enter more deeply into the solar atmosphere, and places where the FUV radiation field is intense, as in flares.

  15. Observational analysis of active region on June, 2000

    NASA Astrophysics Data System (ADS)

    Rovira, M. G.; Luoni, M. L.

    In the recent inaugurated German-Argentinian Solar-Observatory at El Leoncito, a H-alpha Telescope (HASTA) and a mirror coronograph (MICA) are obtained daily images of the solar disk and the inner corona. Since its installation on August 1997, MICA has been imaging the inner corona with high temporal and spatial resolution. Its field-of-view ranges 1.05 to 2.0 solar radii above the sun center. HASTA started operations on May 1998. It has a tunable ( [+1,-1] Å) Lyot-filter with a bandwith of 0.3 Å. In high speed mode full frames can be taken every 2 sec. We study the evolution of an Active Region (AR 9026) and we compare different images as taken in defferent wavelengths. These studies tend to relate flares with coronal mass ejection (CME).

  16. Data-driven Simulations of Evolving Active Regions

    NASA Astrophysics Data System (ADS)

    Cheung, M.; DeRosa, M. L.

    2011-12-01

    We present results from numerical simulations of coronal field evolution in response to photospheric driving. In the simulations, the coronal field evolves according to magnetofriction, which ensures that the model field evolves toward a non-linear force-free state. Unlike static field extrapolation methods, this approach takes into account the history of the photospheric field evolution. This allows for the formation of flux ropes as well as current sheets between magnetic domains of connectivity. Using time sequences of HMI magnetograms as the bottom boundary condition, we apply this method to model the emergence and evolution of various active regions. Comparisons of the models with AIA observations and with HMI vector magnetogram inversions will be discussed.

  17. Slow Magnetosonic Waves and Fast Flows in Active Region Loops

    NASA Technical Reports Server (NTRS)

    Ofman, L.; Wang, T. J.; Davila, J. M.

    2012-01-01

    Recent extreme ultraviolet spectroscopic observations indicate that slow magnetosonic waves are present in active region (AR) loops. Some of the spectral data were also interpreted as evidence of fast (approx 100-300 km/s) quasiperiodic flows. We have performed three-dimensional magnetohydrodynamic (3D MHD) modeling of a bipolar AR that contains impulsively generated waves and flows in coronal loops. The model AR is initiated with a dipole magnetic field and gravitationally stratified density, with an upflow-driven steadily or periodically in localized regions at the footpoints of magnetic loops. The resulting flows along the magnetic field lines of the AR produce higher density loops compared to the surrounding plasma by injection of material into the flux tubes and the establishment of siphon flow.We find that the impulsive onset of flows with subsonic speeds result in the excitation of damped slow magnetosonic waves that propagate along the loops and coupled nonlinearly driven fast-mode waves. The phase speed of the slow magnetosonic waves is close to the coronal sound speed. When the amplitude of the driving pulses is increased we find that slow shock-like wave trains are produced. When the upflows are driven periodically, undamped oscillations are produced with periods determined by the periodicity of the upflows. Based on the results of the 3D MHD model we suggest that the observed slow magnetosonic waves and persistent upflows may be produced by the same impulsive events at the bases of ARs.

  18. SLOW MAGNETOSONIC WAVES AND FAST FLOWS IN ACTIVE REGION LOOPS

    SciTech Connect

    Ofman, L.; Wang, T. J.; Davila, J. M.

    2012-08-01

    Recent extreme ultraviolet spectroscopic observations indicate that slow magnetosonic waves are present in active region (AR) loops. Some of the spectral data were also interpreted as evidence of fast ({approx}100-300 km s{sup -1}) quasi-periodic flows. We have performed three-dimensional magnetohydrodynamic (3D MHD) modeling of a bipolar AR that contains impulsively generated waves and flows in coronal loops. The model AR is initiated with a dipole magnetic field and gravitationally stratified density, with an upflow-driven steadily or periodically in localized regions at the footpoints of magnetic loops. The resulting flows along the magnetic field lines of the AR produce higher density loops compared to the surrounding plasma by injection of material into the flux tubes and the establishment of siphon flow. We find that the impulsive onset of flows with subsonic speeds result in the excitation of damped slow magnetosonic waves that propagate along the loops and coupled nonlinearly driven fast-mode waves. The phase speed of the slow magnetosonic waves is close to the coronal sound speed. When the amplitude of the driving pulses is increased we find that slow shock-like wave trains are produced. When the upflows are driven periodically, undamped oscillations are produced with periods determined by the periodicity of the upflows. Based on the results of the 3D MHD model we suggest that the observed slow magnetosonic waves and persistent upflows may be produced by the same impulsive events at the bases of ARs.

  19. DOME-SHAPED EUV WAVES FROM ROTATING ACTIVE REGIONS

    SciTech Connect

    Selwa, M.; Poedts, S.; DeVore, C. R. E-mail: stefaan.poedts@wis.kuleuven.be

    2012-03-10

    Recent STEREO observations enabled the study of the properties of EUV waves in more detail. They were found to have a three-dimensional (3D) dome-shaped structure. We investigate, by means of 3D MHD simulations, the formation of EUV waves as the result of the interaction of twisted coronal magnetic loops. The numerical simulation is initialized with an idealized dipolar active region and is performed under coronal (low {beta}) conditions. A sheared rotational motion is applied to the central parts of both the positive and negative flux regions at the photosphere so that the flux tubes in between them become twisted. We find that the twisting motion results in a dome-shaped structure followed in space by a dimming and in time by an energy release (flare). The rotation of the sunspots is the trigger of the wave which initially consists of two fronts that later merge together. The resulting EUV wave propagates nearly isotropically on the disk and {approx}2 times faster in the upward direction. The initial stage of the evolution is determined by the driver, while later the wave propagates freely with a nearly Alfvenic speed.

  20. Sunspot waves and triggering of homologous active region jets

    NASA Astrophysics Data System (ADS)

    Chandra, R.; Gupta, G. R.; Mulay, Sargam; Tripathi, Durgesh

    2015-02-01

    We present and discuss multiwavelength observations of five homologous recurrent solar jets that occurred in active region NOAA 11133 on 2010 December 11. These jets were well observed by the Solar Dynamic observatory (SDO) with high spatial and temporal resolution. The speed of the jets ranged between 86 and 267 km s-1. A type III radio burst was observed in association with all the five jets. The investigation of the overall evolution of magnetic field in the source regions suggested that the flux was continuously emerging on longer term. However, all the jets but J5 were triggered during a local dip in the magnetic flux, suggesting the launch of the jets during localized submergence of magnetic flux. Additionally, using the PFSS modelling of the photospheric magnetic field, we found that all the jets were ejected in the direction of open field lines. We also traced sunspot oscillations from the sunspot interior to foot-point of jets and found presence of ˜3 min oscillations in all the SDO/AIA (Atmospheric Imaging Assembly) passbands. The wavelet analysis revealed an increase in amplitude of the oscillations just before the trigger of the jets, that decreased after the jets were triggered. The observations of increased amplitude of the oscillation and its subsequent decrease provides evidence of wave-induced reconnection triggering the jets.

  1. Design for learning: deconstructing virtual patient activities.

    PubMed

    Ellaway, Rachel H; Davies, David

    2011-01-01

    Digital technologies are used in almost every aspect of contemporary health professional education (HPE) but our understanding of their true potential as instructional tools rather than administrative tools has not significantly advanced in the last decade. One notable exception to this has been the rise of the 'virtual patient' as an educational intervention in HPE. This article attempts to deconstruct the virtual patient concept by developing a model of virtual patients as artifacts with intrinsic encoded properties and emergent constructed properties that build on the core concept of 'activity'.

  2. Optimal active vibration absorber: Design and experimental results

    NASA Technical Reports Server (NTRS)

    Lee-Glauser, Gina; Juang, Jer-Nan; Sulla, Jeffrey L.

    1992-01-01

    An optimal active vibration absorber can provide guaranteed closed-loop stability and control for large flexible space structures with collocated sensors/actuators. The active vibration absorber is a second-order dynamic system which is designed to suppress any unwanted structural vibration. This can be designed with minimum knowledge of the controlled system. Two methods for optimizing the active vibration absorber parameters are illustrated: minimum resonant amplitude and frequency matched active controllers. The Controls-Structures Interaction Phase-1 Evolutionary Model at NASA LaRC is used to demonstrate the effectiveness of the active vibration absorber for vibration suppression. Performance is compared numerically and experimentally using acceleration feedback.

  3. Free Magnetic Energy and Helicity in Active and Quiet Solar Regions and their role in Solar

    NASA Astrophysics Data System (ADS)

    Tziotziou, K.; Georgoulis, M. K.; Tsiropoula, G.; Moraitis, K.; Kontogiannis, I.

    2013-09-01

    We present a novel nonlinear force-free method designed to calculate the instantaneous free magnetic energy and relative magnetic helicity budgets of a solar region from a single photospheric/chromospheric vector magnetogram of the region. Our objective is to study the role of these quantities in solar eruptions and quiet-Sun dynamics. We apply the method to (1) derive the energy/helicity diagram of solar active regions from a sample of 162 vector magnetograms corresponding to 42 different active regions (ARs), suggesting that there exist 4 1031 erg and 2 1042 Mx2 thresholds in free energy and relative helicity, respectively, for ARs to enter eruptive territory, (2) study the dynamics of eruptive NOAA AR 11158 using a high-cadence 5-day time series of vector magnetograms, suggesting the formation of increasingly helical pre-eruption structures and a causal relation between flares and Coronal Mass Ejections (CMEs) and, (3) derive helicity and energy budgets in quiet Sun regions and construct the respective energy/helicity diagram. Our results highlight the importance of these two parameters in AR evolution and quiet-Sun dynamics and instigate further research including detailed analysis with synthetic, magnetohydrodynamical models. This work is supported by EU's Seventh Framework Programme via a Marie Curie Fellowship and by the Hellenic National Space Weather Research Network (HNSWRN) via the THALIS Programme.

  4. Long-Period ULF Wave Activity in the Cusp Region

    NASA Astrophysics Data System (ADS)

    Pilipenko, V.; Belakhovsky, V.; Engebretson, M. J.; Kozlovsky, A.

    2013-12-01

    We compare simultaneous observations of long-period ULF wave activity from the Svalbard/IMAGE and Greenland fluxgate magnetometer profiles covering the expected cusp geomagnetic latitudes. Irregular Pulsations at Cusp Latitudes (IPCL) and narrow-band Pc5 waves are found to be a ubiquitous element of ULF activity in the dayside high-latitude region. To identify the ionospheric projections of the cusp, we use the width of the return signal of the SuperDARN radar covering the Svalbard archipelago, predictions of empirical cusp models, and augmented whenever possible by DMSP identification of magnetospheric boundary domains. The meridional spatial structure of IPCL/Pc5 pulsation spectral power has been found to have a localized latitudinal peak, but not under the cusp proper as was previously thought, but several degrees southward from the equatorward cusp boundary. Possible mechanisms and their relevance to observational data are discussed. The occurrence of IPCL and Pc5 waves in the dayside boundary layers is a challenge to modelers, because so far their mechanism has not been firmly identified.

  5. Design of optical coatings for three or more separated spectral regions

    NASA Astrophysics Data System (ADS)

    Dobrowolski, J. A.; Li, L.

    1995-06-01

    A method was described previously that permits the systematic design of optical multilayer coatings with arbitrary spectral characteristics defined for two widely separated spectral regions. It is shown here that this method, based on the use of buffer layers, can be adapted to permit the specification of performance in more than two wavelength ranges. Examples are given of coatings designed for three and four spectral regions. The limitations of the method are discussed.

  6. Regional Triggering of Volcanic Activity Following Large Magnitude Earthquakes

    NASA Astrophysics Data System (ADS)

    Hill-Butler, Charley; Blackett, Matthew; Wright, Robert

    2015-04-01

    There are numerous reports of a spatial and temporal link between volcanic activity and high magnitude seismic events. In fact, since 1950, all large magnitude earthquakes have been followed by volcanic eruptions in the following year - 1952 Kamchatka M9.2, 1960 Chile M9.5, 1964 Alaska M9.2, 2004 & 2005 Sumatra-Andaman M9.3 & M8.7 and 2011 Japan M9.0. While at a global scale, 56% of all large earthquakes (M≥8.0) in the 21st century were followed by increases in thermal activity. The most significant change in volcanic activity occurred between December 2004 and April 2005 following the M9.1 December 2004 earthquake after which new eruptions were detected at 10 volcanoes and global volcanic flux doubled over 52 days (Hill-Butler et al. 2014). The ability to determine a volcano's activity or 'response', however, has resulted in a number of disparities with <50% of all volcanoes being monitored by ground-based instruments. The advent of satellite remote sensing for volcanology has, therefore, provided researchers with an opportunity to quantify the timing, magnitude and character of volcanic events. Using data acquired from the MODVOLC algorithm, this research examines a globally comparable database of satellite-derived radiant flux alongside USGS NEIC data to identify changes in volcanic activity following an earthquake, February 2000 - December 2012. Using an estimate of background temperature obtained from the MODIS Land Surface Temperature (LST) product (Wright et al. 2014), thermal radiance was converted to radiant flux following the method of Kaufman et al. (1998). The resulting heat flux inventory was then compared to all seismic events (M≥6.0) within 1000 km of each volcano to evaluate if changes in volcanic heat flux correlate with regional earthquakes. This presentation will first identify relationships at the temporal and spatial scale, more complex relationships obtained by machine learning algorithms will then be examined to establish favourable

  7. 77 FR 24952 - Agency Information Collection Activities; Proposed Collection; Comment Request; Regional Haze...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-26

    ... ICR (August 26, 2009; 74 FR 43118). The last collection request anticipated the program progressing... AGENCY Agency Information Collection Activities; Proposed Collection; Comment Request; Regional Haze... organizations and facilities potentially regulated under the regional haze rule. Title: Regional...

  8. The morphology of flare phenomena, magnetic fields, and electric currents in active regions. III - NOAA active region 6233 (1990 August)

    NASA Technical Reports Server (NTRS)

    De La Beaujardiere, J.-F.; Canfield, Richard C.; Leka, K. D.

    1993-01-01

    We investigate the spatial relationship between vertical electric currents and flare phenomena in NOAA Active Region 6233, which was observed 1990, August 28-31 at Mees Solar Observatory. The two flares studied are the 1N/M1.8 flare on August 28, 22:30 UT and the 1N/M1.6 flare on August 29, 20:35 UT. Using Stokes polarimetry we make magnetograms of the region and compute the vertical current density. Using H-alpha imaging spectroscopy we identify sites of intense nonthermal electron precipitation or of high coronal pressure. The precipitation in these flares is barely strong enough to be detectable. We find that both precipitation and high pressure tend to occur near vertical currents, but that neither phenomenon is cospatial with current maxima. In contrast with the conclusion of other authors, we argue that these observations do not support a current-interruption model for flares, unless the relevant currents are primarily horizontal. The magnetic morphology and temporal evolution of these flares suggest that an erupting filament model may be relevant, but this model does not explicitly predict the relationship between precipitation, high pressure, and vertical currents.

  9. ON MAGNETIC ACTIVITY BAND OVERLAP, INTERACTION, AND THE FORMATION OF COMPLEX SOLAR ACTIVE REGIONS

    SciTech Connect

    McIntosh, Scott W.; Leamon, Robert J.

    2014-11-20

    Recent work has revealed a phenomenological picture of the how the ∼11 yr sunspot cycle of the Sun arises. The production and destruction of sunspots is a consequence of the latitudinal-temporal overlap and interaction of the toroidal magnetic flux systems that belong to the 22 yr magnetic activity cycle and are rooted deep in the Sun's convective interior. We present a conceptually simple extension of this work, presenting a hypothesis on how complex active regions can form as a direct consequence of the intra- and extra-hemispheric interaction taking place in the solar interior. Furthermore, during specific portions of the sunspot cycle, we anticipate that those complex active regions may be particularly susceptible to profoundly catastrophic breakdown, producing flares and coronal mass ejections of the most severe magnitude.

  10. Contribution of regional brain melanocortin receptor subtypes to elevated activity energy expenditure in lean, active rats.

    PubMed

    Shukla, C; Koch, L G; Britton, S L; Cai, M; Hruby, V J; Bednarek, M; Novak, C M

    2015-12-01

    Physical activity and non-exercise activity thermogenesis (NEAT) are crucial factors accounting for individual differences in body weight, interacting with genetic predisposition. In the brain, a number of neuroendocrine intermediates regulate food intake and energy expenditure (EE); this includes the brain melanocortin (MC) system, consisting of MC peptides as well as their receptors (MCR). MC3R and MC4R have emerged as critical modulators of EE and food intake. To determine how variance in MC signaling may underlie individual differences in physical activity levels, we examined behavioral response to MC receptor agonists and antagonists in rats that show high and low levels of physical activity and NEAT, that is, high- and low-capacity runners (HCR, LCR), developed by artificial selection for differential intrinsic aerobic running capacity. Focusing on the hypothalamus, we identified brain region-specific elevations in expression of MCR 3, 4, and also MC5R, in the highly active, lean HCR relative to the less active and obesity-prone LCR. Further, the differences in activity and associated EE as a result of MCR activation or suppression using specific agonists and antagonists were similarly region-specific and directly corresponded to the differential MCR expression patterns. The agonists and antagonists investigated here did not significantly impact food intake at the doses used, suggesting that the differential pattern of receptor expression may by more meaningful to physical activity than to other aspects of energy balance regulation. Thus, MCR-mediated physical activity may be a key neural mechanism in distinguishing the lean phenotype and a target for enhancing physical activity and NEAT.

  11. Observations of the Growth of an Active Region Filament

    NASA Astrophysics Data System (ADS)

    Yang, Bo; Jiang, Yunchun; Yang, Jiayan; Bi, Yi; Li, Haidong

    2016-10-01

    We present observations of the growth of an active region filament caused by magnetic interactions among the filament and its adjacent superpenumbral filament (SF) and dark thread-like structures (T). Multistep reconnections are identified during the whole growing process. Magnetic flux convergence and cancellation occurring at the positive footpoint region of the filament is the first step reconnection, which resulted in the filament bifurcating into two sets of intertwined threads. One set anchored in situ, while the other set moved toward and interacted with the SF and part of T. This indicates the second step reconnection, which gave rise to the disappearance of the SF and the formation of a long thread-like structure that connects the far ends of the filament and T. The long thread-like structure further interacted with the T and then separated into two parts, representing the third step reconnection. Finally, another similar long thread-like structure, which intertwined with the fixed filament threads, appeared. H α observations show that this twisted structure is a longer sinistral filament. Based on the observed photospheric vector magnetograms, we performed a non-linear force-free field extrapolation to reconstruct the magnetic fields above the photosphere and found that the coronal magnetic field lines associated with the filament consists of two twisted flux ropes winding around each other. These results suggest that magnetic interactions among filaments and their adjacent SFs and T could lead to the growth of the filaments, and the filament is probably supported in a flux rope.

  12. 13 CFR 304.1 - Designation of Economic Development Districts: Regional eligibility.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Designation of Economic Development Districts: Regional eligibility. 304.1 Section 304.1 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF COMMERCE ECONOMIC DEVELOPMENT DISTRICTS § 304.1 Designation...

  13. A Space Weather mission concept: Observatories of the Solar Corona and Active Regions (OSCAR)

    NASA Astrophysics Data System (ADS)

    Strugarek, Antoine; Janitzek, Nils; Lee, Arrow; Löschl, Philipp; Seifert, Bernhard; Hoilijoki, Sanni; Kraaikamp, Emil; Isha Mrigakshi, Alankrita; Philippe, Thomas; Spina, Sheila; Bröse, Malte; Massahi, Sonny; O'Halloran, Liam; Pereira Blanco, Victor; Stausland, Christoffer; Escoubet, Philippe; Kargl, Günter

    2015-02-01

    Coronal Mass Ejections (CMEs) and Corotating Interaction Regions (CIRs) are major sources of magnetic storms on Earth and are therefore considered to be the most dangerous space weather events. The Observatories of Solar Corona and Active Regions (OSCAR) mission is designed to identify the 3D structure of coronal loops and to study the trigger mechanisms of CMEs in solar Active Regions (ARs) as well as their evolution and propagation processes in the inner heliosphere. It also aims to provide monitoring and forecasting of geo-effective CMEs and CIRs. OSCAR would contribute to significant advancements in the field of solar physics, improvements of the current CME prediction models, and provide data for reliable space weather forecasting. These objectives are achieved by utilising two spacecraft with identical instrumentation, located at a heliocentric orbital distance of 1 AU from the Sun. The spacecraft will be separated by an angle of 68° to provide optimum stereoscopic view of the solar corona. We study the feasibility of such a mission and propose a preliminary design for OSCAR.

  14. Salton Sea solar pond power plant design study and regional applicability

    NASA Astrophysics Data System (ADS)

    French, R. L.

    1984-08-01

    Ormat collected and organized the data base and conducted conceptual plant design, performance, and cost analysis. JPL conducted site-specific studies related to solar pond chemistry, soil biological activity, and dike design and construction. WESTEC conducted environmental investigation studies and performed an environmental assessment. SCE provided planning support for licensing and permitting and technical evaluations of the system design and cost estimate.

  15. Salton Sea Solar Pond Power Plant Design Study and Regional Applicability

    NASA Technical Reports Server (NTRS)

    French, R. L.

    1984-01-01

    Ormat collected and organized the data base and conducted conceptual plant design, performance, and cost analysis. JPL conducted site-specific studies related to solar pond chemistry, soil biological activity, and dike design and construction. WESTEC conducted environmental investigation studies and performed an environmental assessment. SCE provided planning support for licensing and permitting and technical evaluations of the system design and cost estimate.

  16. Seismic activity of the San Francisco Bay region

    USGS Publications Warehouse

    Bakun, W.H.

    1999-01-01

    Moment magnitude M with objective confidence-level uncertainties are estimated for felt San Francisco Bay region earthquakes using Bakun and Wentworth's (1997) analysis strategy for seismic intensity observations. The frequency-magnitude distribution is well described for M ???5.5 events since 1850 by a Gutenberg-Richter relation with a b-value of 0.90. The seismic moment rate ??M0/yr since 1836 is 2.68 X 1018 N-m/yr (95% confidence range = 1.29 X 1018 N-m/yr to 4.07 X 1018 N-m/yr); the seismic moment rate since 1850 is nearly the same. ??M0/yr in the 56 years before 1906 is about 10 times that in the 70 years after 1906. In contrast, ??M0/yr since 1977 is about equal that in the 56 years before 1906. 80% (1?? = 14%) of the plate-motion moment accumulation rate is available for release in earthquakes. The historical ??M0/yr and the portion of the plate-motion moment accumulation rate available for release in earthquakes are used in a seismic cycle model to estimate the rate of seismic activity in the twenty-first century. High and low rates of future seismic activity are both permissible given the range of possible seismic-cycle recurrence times T and the uncertainties in the historical ??M0 and in the percentage of plate motion available for release in earthquakes. If the historical seismic moment rate is not greater than the estimated 2.68 X 1018 N-m/yr and the percentage of the plate-motion moment accumulation available for release in earthquakes is not less than the estimated 80%, then for all T, the rate of seismic moment release from now until the next 1906-sized shock will be comparable to the rate from 1836 to 1905 when M 6 1/2 shocks occurred every 15 to 20 years.

  17. FIP BIAS EVOLUTION IN A DECAYING ACTIVE REGION

    SciTech Connect

    Baker, D.; Yardley, S. L.; Driel-Gesztelyi, L. van; Long, D. M.; Green, L. M.; Brooks, D. H.; Démoulin, P.

    2015-04-01

    Solar coronal plasma composition is typically characterized by first ionization potential (FIP) bias. Using spectra obtained by Hinode’s EUV Imaging Spectrometer instrument, we present a series of large-scale, spatially resolved composition maps of active region (AR)11389. The composition maps show how FIP bias evolves within the decaying AR during the period 2012 January 4–6. Globally, FIP bias decreases throughout the AR. We analyzed areas of significant plasma composition changes within the decaying AR and found that small-scale evolution in the photospheric magnetic field is closely linked to the FIP bias evolution observed in the corona. During the AR’s decay phase, small bipoles emerging within supergranular cells reconnect with the pre-existing AR field, creating a pathway along which photospheric and coronal plasmas can mix. The mixing timescales are shorter than those of plasma enrichment processes. Eruptive activity also results in shifting the FIP bias closer to photospheric in the affected areas. Finally, the FIP bias still remains dominantly coronal only in a part of the AR’s high-flux density core. We conclude that in the decay phase of an AR’s lifetime, the FIP bias is becoming increasingly modulated by episodes of small-scale flux emergence, i.e., decreasing the AR’s overall FIP bias. Our results show that magnetic field evolution plays an important role in compositional changes during AR development, revealing a more complex relationship than expected from previous well-known Skylab results showing that FIP bias increases almost linearly with age in young ARs.

  18. A Preliminary Interaction Region Design for a Super B-Factory

    SciTech Connect

    Sullivan, M.; Donald, M.; Ecklund, S.; Novokhatski, A.; Seeman, J.; Wienands, U.; Biagini, M.; /Frascati

    2005-06-10

    The success of the two B-Factories (PEP-II and KEKB) has encouraged us to look at design parameters for a B-Factory with a 30-50 times increase in the luminosity of the present machines to a luminosity of L {approx} 1 x 10{sup 36} cm{sup -2} sec{sup -1}. We present an initial design of an interaction region for a ''SuperB'' accelerator with a crossing angle of {+-}14 mrad and include a discussion of the constraints, requirements and concerns that go into designing an interaction region for these very high luminosity e{sup +}e{sup -} machines.

  19. Optimal design of multiple stress constant accelerated life test plan on non-rectangle test region

    NASA Astrophysics Data System (ADS)

    Chen, Wenhua; Gao, Liang; Liu, Juan; Qian, Ping; Pan, Jun

    2012-11-01

    For optimal design of constant stress accelerated life test(CSALT) with two-stress, if the stresses could not reach the highest levels simultaneously, the test region becomes non-rectangular. For optimal CSALT design on non-rectangle test region, the present method is only focused on non-rectangle test region with simple boundary, and the optimization algorithm is based on experience which can not ensure to obtain the optimal plan. In this paper, considering the linear-extreme value model and the optimization goal to minimize the variance of lifetime estimate under normal stress, the optimal design method of two-stress type-I censored CSALT plan on general non-rectangular test region is proposed. First, two properties of optimal test plans are proved and the relationship of all the optimal test plans is determined analytically. Then, on the basis of the two properties, the optimal problem is simplified and the optimal design method of two-stress CSALT plan on general non-rectangular test region is proposed. Finally, a numerical example is used to illustrate the feasibility and effectiveness of the method. The result shows that the proposed method could obtain the optimal test plan on non-rectangular test regions with arbitrary boundaries. This research provides the theory and method for two-stress optimal CSALT planning on non-rectangular test regions.

  20. Acetylcholine activity in selective striatal regions supports behavioral flexibility.

    PubMed

    Ragozzino, Michael E; Mohler, Eric G; Prior, Margaret; Palencia, Carlos A; Rozman, Suzanne

    2009-01-01

    Daily living often requires individuals to flexibly respond to new circumstances. There is considerable evidence that the striatum is part of a larger neural network that supports flexible adaptations. Cholinergic interneurons are situated to strongly influence striatal output patterns which may enable flexible adaptations. The present experiments investigated whether acetylcholine actions in different striatal regions support behavioral flexibility by measuring acetylcholine efflux during place reversal learning. Acetylcholine efflux selectively increased in the dorsomedial striatum, but not dorsolateral or ventromedial striatum during place reversal learning. In order to modulate the M2-class of autoreceptors, administration of oxotremorine sesquifumurate (100 nM) into the dorsomedial striatum, concomitantly impaired reversal learning and an increase in acetylcholine output. These effects were reversed by the m(2) muscarinic receptor antagonist, AF-DX-116 (20 nM). The effects of oxotremorine sesquifumurate and AF-DX-116 on acetylcholine efflux were selective to behaviorally-induced changes as neither treatment affected acetylcholine output in a resting condition. In contrast to reversal learning, acetylcholine efflux in the dorsomedial striatum did not change during place acquisition. The results reveal an essential role for cholinergic activity and define its locus of control to the dorsomedial striatum in cognitive flexibility.

  1. SIMULATION OF THE FORMATION OF A SOLAR ACTIVE REGION

    SciTech Connect

    Cheung, M. C. M.; Title, A. M.; Rempel, M.; Schuessler, M.

    2010-09-01

    We present a radiative magnetohydrodynamics simulation of the formation of an active region (AR) on the solar surface. The simulation models the rise of a buoyant magnetic flux bundle from a depth of 7.5 Mm in the convection zone up into the solar photosphere. The rise of the magnetic plasma in the convection zone is accompanied by predominantly horizontal expansion. Such an expansion leads to a scaling relation between the plasma density and the magnetic field strength such that B {proportional_to} rhov{sup 1/2}. The emergence of magnetic flux into the photosphere appears as a complex magnetic pattern, which results from the interaction of the rising magnetic field with the turbulent convective flows. Small-scale magnetic elements at the surface first appear, followed by their gradual coalescence into larger magnetic concentrations, which eventually results in the formation of a pair of opposite polarity spots. Although the mean flow pattern in the vicinity of the developing spots is directed radially outward, correlations between the magnetic field and velocity field fluctuations allow the spots to accumulate flux. Such correlations result from the Lorentz-force-driven, counterstreaming motion of opposite polarity fragments. The formation of the simulated AR is accompanied by transient light bridges between umbrae and umbral dots. Together with recent sunspot modeling, this work highlights the common magnetoconvective origin of umbral dots, light bridges, and penumbral filaments.

  2. Plasma composition in a sigmoidal anemone active region

    SciTech Connect

    Baker, D.; Van Driel-Gesztelyi, L.; Green, L. M.; Carlyle, J.; Brooks, D. H.; Démoulin, P.; Steed, K.

    2013-11-20

    Using spectra obtained by the EUV Imaging Spectrometer (EIS) instrument onboard Hinode, we present a detailed spatially resolved abundance map of an active region (AR)-coronal hole (CH) complex that covers an area of 359'' × 485''. The abundance map provides first ionization potential (FIP) bias levels in various coronal structures within the large EIS field of view. Overall, FIP bias in the small, relatively young AR is 2-3. This modest FIP bias is a consequence of the age of the AR, its weak heating, and its partial reconnection with the surrounding CH. Plasma with a coronal composition is concentrated at AR loop footpoints, close to where fractionation is believed to take place in the chromosphere. In the AR, we found a moderate positive correlation of FIP bias with nonthermal velocity and magnetic flux density, both of which are also strongest at the AR loop footpoints. Pathways of slightly enhanced FIP bias are traced along some of the loops connecting opposite polarities within the AR. We interpret the traces of enhanced FIP bias along these loops to be the beginning of fractionated plasma mixing in the loops. Low FIP bias in a sigmoidal channel above the AR's main polarity inversion line, where ongoing flux cancellation is taking place, provides new evidence of a bald patch magnetic topology of a sigmoid/flux rope configuration.

  3. Plasma Composition in a Sigmoidal Anemone Active Region

    NASA Astrophysics Data System (ADS)

    Baker, D.; Brooks, D. H.; Démoulin, P.; van Driel-Gesztelyi, L.; Green, L. M.; Steed, K.; Carlyle, J.

    2013-11-01

    Using spectra obtained by the EUV Imaging Spectrometer (EIS) instrument onboard Hinode, we present a detailed spatially resolved abundance map of an active region (AR)-coronal hole (CH) complex that covers an area of 359'' × 485''. The abundance map provides first ionization potential (FIP) bias levels in various coronal structures within the large EIS field of view. Overall, FIP bias in the small, relatively young AR is 2-3. This modest FIP bias is a consequence of the age of the AR, its weak heating, and its partial reconnection with the surrounding CH. Plasma with a coronal composition is concentrated at AR loop footpoints, close to where fractionation is believed to take place in the chromosphere. In the AR, we found a moderate positive correlation of FIP bias with nonthermal velocity and magnetic flux density, both of which are also strongest at the AR loop footpoints. Pathways of slightly enhanced FIP bias are traced along some of the loops connecting opposite polarities within the AR. We interpret the traces of enhanced FIP bias along these loops to be the beginning of fractionated plasma mixing in the loops. Low FIP bias in a sigmoidal channel above the AR's main polarity inversion line, where ongoing flux cancellation is taking place, provides new evidence of a bald patch magnetic topology of a sigmoid/flux rope configuration.

  4. Active region emission measure distributions and implications for nanoflare heating

    SciTech Connect

    Cargill, P. J.

    2014-03-20

    The temperature dependence of the emission measure (EM) in the core of active regions coronal loops is an important diagnostic of heating processes. Observations indicate that EM(T) ∼ T{sup a} below approximately 4 MK, with 2 < a < 5. Zero-dimensional hydrodynamic simulations of nanoflare trains are used to demonstrate the dependence of a on the time between individual nanoflares (T{sub N} ) and the distribution of nanoflare energies. If T{sub N} is greater than a few thousand seconds, a < 3. For smaller values, trains of equally spaced nanoflares cannot account for the observed range of a if the distribution of nanoflare energies is either constant, randomly distributed, or a power law. Power law distributions where there is a delay between consecutive nanoflares proportional to the energy of the second nanoflare do lead to the observed range of a. However, T{sub N} must then be of the order of hundreds to no more than a few thousand seconds. If a nanoflare leads to the relaxation of a stressed coronal field to a near-potential state, the time taken to build up the required magnetic energy is thus too long to account for the EM measurements. Instead, it is suggested that a nanoflare involves the relaxation from one stressed coronal state to another, dissipating only a small fraction of the available magnetic energy. A consequence is that nanoflare energies may be smaller than previously envisioned.

  5. The distribution of maximum temperatures of coronal active region loops

    NASA Technical Reports Server (NTRS)

    Mayfield, E. B.; Teske, R. G.

    1980-01-01

    The emission measure distribution across the range 4.5 log T 6.5 was derived for several coronal active regions by combining EUV line fluxes with broadband X-ray fluxes. The distributions of the maximum temperature was then derived using a numerical model. It is shown that the emission measure distribution can be represented over the full range 5.6 log Tm 6.5 by the superposition of simple loop models, if the models incorporate a substantial rise in their individual emission measure distributions near the maximum temperature. The unresolved loops may have substantial area ratios, since it is this ratio that fixes the extent of the rise in the emission measure distribution. Since the bulk of the emission measure is then contributed from the loop tops, the distribution of maximum temperatures has approximately the same shape as does the integrated emission measure distributions. The EUV and X-ray data used were obtained by from two separate experiments on ATM/Skylab.

  6. Geometry of Broad Line Regions of Active Galactic Nuclei

    NASA Astrophysics Data System (ADS)

    Lü, Xiao-Rong

    2008-02-01

    It has long remained an open question as to the geometry of the broad line region (BLR) in active galactic nuclei (AGNs). The reverberation mapping technique which measures the response of the broad emission lines to the ionizing continuum, when combined with multiwavelength continuum fitted by sophisticated accretion disks, provides a way of probing the BLR geometry. We analyze a sample of 35 AGNs, which have been monitored by the reverberation mapping campaign. In view of energy budget, the reverberation-based BH masses are found to be in agreement with those obtained by accretion disk models in two thirds of the present sample while the reverberation mapping methods underestimate the BH masses in about one third of objects, as also suggested by Collin et al. in a recent work. We point out that there are obviously two kinds of BLR geometry, which are strongly dependent on the Eddington ratio, and separated by the value LBol/LEdd~0.1. These results prefer a scenario of the disk and wind configuration of the BLR and identify the Eddington ratio as the physical driver regulating the wind in the BLR.

  7. Simulation of the Formation of a Solar Active Region

    NASA Astrophysics Data System (ADS)

    Cheung, M. C. M.; Rempel, M.; Title, A. M.; Schüssler, M.

    2010-09-01

    We present a radiative magnetohydrodynamics simulation of the formation of an active region (AR) on the solar surface. The simulation models the rise of a buoyant magnetic flux bundle from a depth of 7.5 Mm in the convection zone up into the solar photosphere. The rise of the magnetic plasma in the convection zone is accompanied by predominantly horizontal expansion. Such an expansion leads to a scaling relation between the plasma density and the magnetic field strength such that B vprop rhov1/2. The emergence of magnetic flux into the photosphere appears as a complex magnetic pattern, which results from the interaction of the rising magnetic field with the turbulent convective flows. Small-scale magnetic elements at the surface first appear, followed by their gradual coalescence into larger magnetic concentrations, which eventually results in the formation of a pair of opposite polarity spots. Although the mean flow pattern in the vicinity of the developing spots is directed radially outward, correlations between the magnetic field and velocity field fluctuations allow the spots to accumulate flux. Such correlations result from the Lorentz-force-driven, counterstreaming motion of opposite polarity fragments. The formation of the simulated AR is accompanied by transient light bridges between umbrae and umbral dots. Together with recent sunspot modeling, this work highlights the common magnetoconvective origin of umbral dots, light bridges, and penumbral filaments.

  8. THE ORIGIN OF NET ELECTRIC CURRENTS IN SOLAR ACTIVE REGIONS

    SciTech Connect

    Dalmasse, K.; Kliem, B.; Török, T.

    2015-09-01

    There is a recurring question in solar physics regarding whether or not electric currents are neutralized in active regions (ARs). This question was recently revisited using three-dimensional (3D) magnetohydrodynamic (MHD) numerical simulations of magnetic flux emergence into the solar atmosphere. Such simulations showed that flux emergence can generate a substantial net current in ARs. Other sources of AR currents are photospheric horizontal flows. Our aim is to determine the conditions for the occurrence of net versus neutralized currents with this second mechanism. Using 3D MHD simulations, we systematically impose line-tied, quasi-static, photospheric twisting and shearing motions to a bipolar potential magnetic field. We find that such flows: (1) produce both direct and return currents, (2) induce very weak compression currents—not observed in 2.5D—in the ambient field present in the close vicinity of the current-carrying field, and (3) can generate force-free magnetic fields with a net current. We demonstrate that neutralized currents are in general produced only in the absence of magnetic shear at the photospheric polarity inversion line—a special condition that is rarely observed. We conclude that  photospheric flows, as magnetic flux emergence, can build up net currents in the solar atmosphere, in agreement with recent observations. These results thus provide support for eruption models based on pre-eruption magnetic fields that possess a net coronal current.

  9. Practical Design Activities for Your Technology Education Classes

    ERIC Educational Resources Information Center

    Berkeihiser, Mike

    2006-01-01

    In this article, the author relates how he and his class get involved in doing project designs within their school district every year. The author relates how they have done design projects for local townships and boroughs, non-profit organizations, Eagle Scout projects, and much more. The author relates how these activities have been such…

  10. Bedroom design and decoration: gender differences in preference and activity.

    PubMed

    Jones, Randall M; Taylor, Denise E; Dick, Andrew J; Singh, Archana; Cook, Jerry L

    2007-01-01

    This investigation examined gender differences in niche-building preference and activity among 238 8th and 9th grade boys and girls. A questionnaire was developed to measure both the actual and preferred bedroom content, bedroom design activity, and the level of perceived influence by the immediate and extended family, friends, and social institutions. Gender differences were identified for preference, activity, and influence in bedroom design and decoration. Girls and boys differed in the type of items contained in their bedrooms. Girls' rooms contained stuffed animals and pictures of people, including themselves, more frequently than the boys' rooms. In contrast, boys' rooms contained sports-related items, and things for building or that they had built themselves. Although bedroom design activity for both boys and girls was influenced by older teens, friends, media, and popular culture, boys (but not girls) were also influenced by their mothers, fathers, girlfriends, and activities such as sports, Boy or Girl Scouts, and music lessons.

  11. Bedroom design and decoration: gender differences in preference and activity.

    PubMed

    Jones, Randall M; Taylor, Denise E; Dick, Andrew J; Singh, Archana; Cook, Jerry L

    2007-01-01

    This investigation examined gender differences in niche-building preference and activity among 238 8th and 9th grade boys and girls. A questionnaire was developed to measure both the actual and preferred bedroom content, bedroom design activity, and the level of perceived influence by the immediate and extended family, friends, and social institutions. Gender differences were identified for preference, activity, and influence in bedroom design and decoration. Girls and boys differed in the type of items contained in their bedrooms. Girls' rooms contained stuffed animals and pictures of people, including themselves, more frequently than the boys' rooms. In contrast, boys' rooms contained sports-related items, and things for building or that they had built themselves. Although bedroom design activity for both boys and girls was influenced by older teens, friends, media, and popular culture, boys (but not girls) were also influenced by their mothers, fathers, girlfriends, and activities such as sports, Boy or Girl Scouts, and music lessons. PMID:18047237

  12. A novel lead design enables selective deep brain stimulation of neural populations in the subthalamic region

    NASA Astrophysics Data System (ADS)

    van Dijk, Kees J.; Verhagen, Rens; Chaturvedi, Ashutosh; McIntyre, Cameron C.; Bour, Lo J.; Heida, Ciska; Veltink, Peter H.

    2015-08-01

    Objective. The clinical effects of deep brain stimulation (DBS) of the subthalamic nucleus (STN-DBS) as a treatment for Parkinson’s disease are sensitive to the location of the DBS lead within the STN. New high density (HD) lead designs have been created which are hypothesized to provide additional degrees of freedom in shaping the stimulating electric field. The objective of this study is to compare the performances of a new HD lead with a conventional cylindrical contact (CC) lead. Approach. A computational model, consisting of a finite element electric field model combined with multi-compartment neuron and axon models representing different neural populations in the subthalamic region, was used to evaluate the two leads. We compared ring-mode and steering-mode stimulation with the HD lead to single contact stimulation with the CC lead. These stimulation modes were tested for the lead: (1) positioned in the centroid of the STN, (2) shifted 1 mm towards the internal capsule (IC), and (3) shifted 2 mm towards the IC. Under these conditions, we quantified the number of STN neurons that were activated without activating IC fibers, which are known to cause side-effects. Main results. The modeling results show that the HD lead is able to mimic the stimulation effect of the CC lead. Additionally, in steering-mode stimulation there was a significant increase of activated STN neurons compared to the CC mode. Significance. From the model simulations we conclude that the HD lead in steering-mode with optimized stimulation parameter selection can stimulate more STN cells. Next, the clinical impact of the increased number of activated STN cells should be tested and balanced across the increased complexity of identifying the optimized stimulation parameter settings for the HD lead.

  13. 24-Hour Forecasting of CME/Flare Eruptions from Active-Region Magnetograms (Invited)

    NASA Astrophysics Data System (ADS)

    Falconer, D. A.; Barghouty, A.; Khazanov, I. G.; Moore, R. L.

    2010-12-01

    We have developed an automated tool for forecasting severe space weather from full-disk magnetograms. This tool is now being used on a trial basis by NASA’s Space Radiation Analysis Group (SRAG) at JSC. SRAG is responsible for the monitoring and forecasting of exposure the astronauts to particle radiation. The tool is described in Falconer, Barghouty, Khazanov, and Moore (2010), submitted to Space Weather. The new software tool is designed for the empirical forecasting of M- and X-class flares, coronal mass ejections, and solar energetic particle events. For each of these event types, the algorithm is based on the empirical relationship between the event rate and a proxy of the active region’s free magnetic energy. The relationship is determined from ~40,000 active-region magnetograms from ~1,300 active regions that were observed within 30 heliographic degrees from disk center by SOHO/MDI, and that have known histories of flare, coronal mass ejection, and solar energetic particle event production during disk passage. The tool automatically extracts each strong-field magnetic areas from an MDI full-disk magnetogram, identifies each as a NOAA active region, and measures the proxy of the active region’s free magnetic energy from the extracted magnetogram. For each active region, the empirical relationship is then used to convert the free magnetic energy proxy into the active region’s expected event rate (see figure). The expected event rate in turn can be readily converted into the probability that the active region will produce such an event in a given forward time window. We can make this tool applicable to the full-disk line-of-sight magnetograms from SDO/HMI or as a backup, from NSO/GONG. By empirically determining the conversion of the value of free-energy proxy measured from an HMI magnetogram to that which would be measured from an MDI magnetogram, we can use the HMI magnetograms with the empirical relationships determined from our MDI data base to make

  14. Bedroom Design and Decoration: Gender Differences in Preference and Activity

    ERIC Educational Resources Information Center

    Jones, Randall M.; Taylor, Denise E.; Dick, Andrew J.; Singh, Archana; Cook, Jerry L.

    2007-01-01

    This investigation examined gender differences in niche-building preference and activity among 238 8th and 9th grade boys and girls. A questionnaire was developed to measure both the actual and preferred bedroom content, bedroom design activity, and the level of perceived influence by the immediate and extended family, friends, and social…

  15. Design of Activities on Numerical Representations Based on Cognitive Research

    ERIC Educational Resources Information Center

    Kalifatidou, Eleftheria R.

    2008-01-01

    The results of the cognitive research on numbers' representations can provide a sound theoretical framework to develop educational activities on representing numbers. A program of such activities for a nursery school was designed in order to enable the children to externalize and strengthen their internal representations about numerosity and link…

  16. Supporting "Learning by Design" Activities Using Group Blogs

    ERIC Educational Resources Information Center

    Fessakis, Georgios; Tatsis, Konstantinos; Dimitracopoulou, Angelique

    2008-01-01

    The paper presents a case study of the educational exploitation of group blogging for the implementation of a "learning by design" activity. More specifically, a group of students used a blog as a communication and information management tool in the University course of ICT-enhanced Geometry learning activities. The analysis of the designed…

  17. The discourse of design-based science classroom activities

    NASA Astrophysics Data System (ADS)

    Azevedo, Flávio S.; Martalock, Peggy L.; Keser, Tugba

    2015-06-01

    This paper is an initial contribution to a general theory in which science classroom activity types and epistemological discourse practices are systematically linked. The idea is that activities and discourse are reflexively related, so that different types of science classroom activities (e.g., scientific argumentation, modeling, and design) recruit characteristically distinct forms of participants' (students and teacher) discourse. Such a general theory would eventually map out the full spectrum of discourse practices (and their patterns of manifestation) across various kinds of science classroom activities, and reveal new relationships between forms of both discourse and activities. Because this defines a complex and long-term project, here our aim is simply to delineate this larger theoretical program and to illustrate it with a detailed case study—namely, that of mapping out and characterizing the discourse practices of design- based science classroom activities. To do so, we draw on data from an activity that is prototypically design-based—i.e., one in which students iteratively design and refine an artifact (in this case, pictorial representations of moving objects)—and examine the structure and dynamics of the whole-class discourse practices that emerge around these representational forms. We then compare and contrast these discourse practices to those of an activity that is prototypical of scientific argumentation (taken from the literature)—i.e., one in which students argue between competing theories and explanations of a phenomenon—and begin to illustrate the kinds of insights our theoretical program might afford.

  18. Engineering Design Activities and Conceptual Change in Middle School Science

    ERIC Educational Resources Information Center

    Schnittka, Christine G.

    2009-01-01

    The purpose of this research was to investigate the impact of engineering design classroom activities on conceptual change in science, and on attitudes toward and knowledge about engineering. Students were given a situated learning context and a rationale for learning science in an active, inquiry-based method, and worked in small collaborative…

  19. Design and Implementation of an Object Oriented Learning Activity System

    ERIC Educational Resources Information Center

    Lin, Huan-Yu; Tseng, Shian-Shyong; Weng, Jui-Feng; Su, Jun-Ming

    2009-01-01

    With the development of e-learning technology, many specifications of instructional design have been proposed to make learning activity sharable and reusable. With the specifications and sufficient learning resources, the researches further focus on how to provide learners more appropriate learning activities to improve their learning performance.…

  20. MAGNETIC HELICITY AND ENERGY SPECTRA OF A SOLAR ACTIVE REGION

    SciTech Connect

    Zhang, Hongqi; Brandenburg, Axel; Sokoloff, D. D.

    2014-04-01

    We compute for the first time the magnetic helicity and energy spectra of the solar active region NOAA 11158 during 2011 February 11-15 at 20° southern heliographic latitude using observational photospheric vector magnetograms. We adopt the isotropic representation of the Fourier-transformed two-point correlation tensor of the magnetic field. The sign of the magnetic helicity turns out to be predominantly positive at all wavenumbers. This sign is consistent with what is theoretically expected for the southern hemisphere. The magnetic helicity normalized to its theoretical maximum value, here referred to as relative helicity, is around 4% and strongest at intermediate wavenumbers of k ≈ 0.4 Mm{sup –1}, corresponding to a scale of 2π/k ≈ 16 Mm. The same sign and a similar value are also found for the relative current helicity evaluated in real space based on the vertical components of magnetic field and current density. The modulus of the magnetic helicity spectrum shows a k {sup –11/3} power law at large wavenumbers, which implies a k {sup –5/3} spectrum for the modulus of the current helicity. A k {sup –5/3} spectrum is also obtained for the magnetic energy. The energy spectra evaluated separately from the horizontal and vertical fields agree for wavenumbers below 3 Mm{sup –1}, corresponding to scales above 2 Mm. This gives some justification to our assumption of isotropy and places limits resulting from possible instrumental artifacts at small scales.

  1. CONTRACTING AND ERUPTING COMPONENTS OF SIGMOIDAL ACTIVE REGIONS

    SciTech Connect

    Liu Rui; Wang Yuming; Liu Chang; Wang Haimin; Toeroek, Tibor

    2012-10-01

    It has recently been noted that solar eruptions can be associated with the contraction of coronal loops that are not involved in magnetic reconnection processes. In this paper, we investigate five coronal eruptions originating from four sigmoidal active regions, using high-cadence, high-resolution narrowband EUV images obtained by the Solar Dynamic Observatory (SDO). The magnitudes of the flares associated with the eruptions range from GOES class B to class X. Owing to the high-sensitivity and broad temperature coverage of the Atmospheric Imaging Assembly (AIA) on board SDO, we are able to identify both the contracting and erupting components of the eruptions: the former is observed in cold AIA channels as the contracting coronal loops overlying the elbows of the sigmoid, and the latter is preferentially observed in warm/hot AIA channels as an expanding bubble originating from the center of the sigmoid. The initiation of eruption always precedes the contraction, and in the energetically mild events (B- and C-flares), it also precedes the increase in GOES soft X-ray fluxes. In the more energetic events, the eruption is simultaneous with the impulsive phase of the nonthermal hard X-ray emission. These observations confirm that loop contraction is an integrated process in eruptions with partially opened arcades. The consequence of contraction is a new equilibrium with reduced magnetic energy, as the contracting loops never regain their original positions. The contracting process is a direct consequence of flare energy release, as evidenced by the strong correlation of the maximal contracting speed, and strong anti-correlation of the time delay of contraction relative to expansion, with the peak soft X-ray flux. This is also implied by the relationship between contraction and expansion, i.e., their timing and speed.

  2. Identifying the Main Driver of Active Region Outflows

    NASA Astrophysics Data System (ADS)

    Baker, D.; van Driel-Gesztelyi, L.; Mandrini, C. H.; Démoulin, P.; Murray, M. J.

    2012-08-01

    Hinode's EUV Imaging Spectrometer (EIS) has discovered ubiquitous outflows of a few to 50 km s-1 from active regions (ARs). The characteristics of these outflows are very curious in that they are most prominent at the AR boundary and appear over monopolar magnetic areas. They are linked to strong non-thermal line broadening and are stronger in hotter EUV lines. The outflows persist for at least several days. Whereas red-shifted down flows observed in AR closed loops are well understood, to date there is no general consensus for the mechanism(s) driving blue-shifted AR-related outflows. We use Hinode EIS and X-Ray Telescope observations of AR 10942 coupled with magnetic modeling to demonstrate for the first time that the outflows originate from specific locations of the magnetic topology where field lines display strong gradients of magnetic connectivity, namely quasi-separatrix layers (QSLs), or in the limit of infinitely thin QSLs, separatrices. The strongest AR outflows were found to be in the vicinity of QSL sections located over areas of strong magnetic field. We argue that magnetic reconnection at QSLs, separating closed field lines of the AR and either large-scale externally connected or ‘open’ field lines, is a viable mechanism for driving AR outflows which are potentially sources of the slow solar wind. In fact, magnetic reconnection along QSLs (including separatricies) is the first theory to explain the most puzzling characteristics of the outflows, namely their occurrence over monopolar areas at the periphery of ARs and their longevity.

  3. ABRUPT LONGITUDINAL MAGNETIC FIELD CHANGES IN FLARING ACTIVE REGIONS

    SciTech Connect

    Petrie, G. J. D.; Sudol, J. J.

    2010-12-01

    We characterize the changes in the longitudinal photospheric magnetic field during 38 X-class and 39 M-class flares within 65{sup 0} of disk center using 1 minute GONG magnetograms. In all 77 cases, we identify at least one site in the flaring active region where clear, permanent, stepwise field changes occurred. The median duration of the field changes was about 15 minutes and was approximately equal for X-class and for M-class flares. The absolute values of the field changes ranged from the detection limit of {approx}10 G to as high as {approx}450 G in two exceptional cases. The median value was 69 G. Field changes were significantly stronger for X-class than for M-class flares and for limb flares than for disk-center flares. Longitudinal field changes less than 100 G tended to decrease longitudinal field strengths, both close to disk center and close to the limb, while field changes greater than 100 G showed no such pattern. Likewise, longitudinal flux strengths tended to decrease during flares. Flux changes, particularly net flux changes near disk center, correlated better than local field changes with GOES peak X-ray flux. The strongest longitudinal field and flux changes occurred in flares observed close to the limb. We estimate the change of Lorentz force associated with each flare and find that this is large enough in some cases to power seismic waves. We find that longitudinal field decreases would likely outnumber increases at all parts of the solar disk within 65{sup 0} of disk center, as in our observations, if photospheric field tilts increase during flares as predicted by Hudson et al.

  4. ON THE ROLE OF ROTATING SUNSPOTS IN THE ACTIVITY OF SOLAR ACTIVE REGION NOAA 11158

    SciTech Connect

    Vemareddy, P.; Ambastha, A.; Maurya, R. A. E-mail: ambastha@prl.res.in

    2012-12-10

    We study the role of rotating sunspots in relation to the evolution of various physical parameters characterizing the non-potentiality of the active region (AR) NOAA 11158 and its eruptive events using the magnetic field data from the Helioseismic and Magnetic Imager (HMI) and multi-wavelength observations from the Atmospheric Imaging Assembly (AIA) on board the Solar Dynamics Observatory. From the evolutionary study of HMI intensity and AIA channels, it is observed that the AR consists of two major rotating sunspots, one connected to a flare-prone region and another with coronal mass ejection (CME). The constructed space-time intensity maps reveal that the sunspots exhibited peak rotation rates coinciding with the occurrence of major eruptive events. Further, temporal profiles of twist parameters, namely, average shear angle, {alpha}{sub av}, {alpha}{sub best}, derived from HMI vector magnetograms, and the rate of helicity injection, obtained from the horizontal flux motions of HMI line-of-sight magnetograms, correspond well with the rotational profile of the sunspot in the CME-prone region, giving predominant evidence of rotational motion causing magnetic non-potentiality. Moreover, the mean value of free energy from the virial theorem calculated at the photospheric level shows a clear step-down decrease at the onset time of the flares revealing unambiguous evidence of energy release intermittently that is stored by flux emergence and/or motions in pre-flare phases. Additionally, distribution of helicity injection is homogeneous in the CME-prone region while in the flare-prone region it is not and often changes sign. This study provides a clear picture that both proper and rotational motions of the observed fluxes played significant roles in enhancing the magnetic non-potentiality of the AR by injecting helicity, twisting the magnetic fields and thereby increasing the free energy, leading to favorable conditions for the observed transient activity.

  5. The Maximum Free Magnetic Energy Allowed in a Solar Active Region

    NASA Astrophysics Data System (ADS)

    Moore, Ronald L.; Falconer, D. A.

    2009-05-01

    Two whole-active-region magnetic quantities that can be measured from a line-of-sight magnetogram are LWLSG, a gauge of the total free energy in an active region's magnetic field, and LΦ, a measure of the active region's total magnetic flux. From these two quantities measured from 1865 SOHO/MDI magnetograms that tracked 44 sunspot active regions across the 0.5 RSun central disk, together with each active region's observed production of CMEs, X flares, and M flares, Falconer et al (2009, ApJ, submitted) found that (1) active regions have a maximum attainable free magnetic energy that increases with the magnetic size LΦ of the active region, (2) in (Log LWLSG, Log LΦ) space, CME/flare-productive active regions are concentrated in a straight-line main sequence along which the free magnetic energy is near its upper limit, and (3) X and M flares are restricted to large active regions. Here, from (a) these results, (b) the observation that even the greatest X flares produce at most only subtle changes in active-region magnetograms, and (c) measurements from MSFC vector magnetograms and from MDI line-of-sight magnetograms showing that practically all sunspot active regions have nearly the same area-averaged magnetic field strength: áBñ ≡ ΦA ≈ 300 G, where Φ is the active region's total photospheric flux of field stronger than 100 G and A is the area of that flux, we infer that (1) the maximum allowed ratio of an active region's free magnetic energy to its potential-field energy is 1, and (2) any one CME/flare eruption releases no more than a small fraction (< 10%) of the active region's free magnetic energy. This work was funded by NASA's Heliophysics Division, NSF's Division of Atmospheric Sciences, and AFOSR's MURI Program.

  6. The Maximum Free Magnetic Energy Allowed in a Solar Active Region

    NASA Technical Reports Server (NTRS)

    Moore, Ronald L.; Falconer, David A.

    2009-01-01

    Two whole-active-region magnetic quantities that can be measured from a line-of-sight magnetogram are (sup L) WL(sub SG), a gauge of the total free energy in an active region's magnetic field, and sup L(sub theta), a measure of the active region's total magnetic flux. From these two quantities measured from 1865 SOHO/MDI magnetograms that tracked 44 sunspot active regions across the 0.5 R(sub Sun) central disk, together with each active region's observed production of CMEs, X flares, and M flares, Falconer et al (2009, ApJ, submitted) found that (1) active regions have a maximum attainable free magnetic energy that increases with the magnetic size (sup L) (sub theta) of the active region, (2) in (Log (sup L)WL(sub SG), Log(sup L) theta) space, CME/flare-productive active regions are concentrated in a straight-line main sequence along which the free magnetic energy is near its upper limit, and (3) X and M flares are restricted to large active regions. Here, from (a) these results, (b) the observation that even the greatest X flares produce at most only subtle changes in active region magnetograms, and (c) measurements from MSFC vector magnetograms and from MDI line-of-sight magnetograms showing that practically all sunspot active regions have nearly the same area-averaged magnetic field strength: =- theta/A approximately equal to 300 G, where theta is the active region's total photospheric flux of field stronger than 100 G and A is the area of that flux, we infer that (1) the maximum allowed ratio of an active region's free magnetic energy to its potential-field energy is 1, and (2) any one CME/flare eruption releases no more than a small fraction (less than 10%) of the active region's free magnetic energy. This work was funded by NASA's Heliophysics Division and NSF's Division of Atmospheric Sciences.

  7. Design and Implementation of a Project-Based Active/Cooperative Engineering Design Course for Freshmen

    ERIC Educational Resources Information Center

    Abdulaal, R. M.; Al-Bahi, A. M.; Soliman, A. Y.; Iskanderani, F. I.

    2011-01-01

    A project-based active/cooperative design course is planned, implemented, assessed and evaluated to achieve several desired engineering outcomes. The course allows freshman-level students to gain professional hands-on engineering design experience through an opportunity to practise teamwork, quality principles, communication skills, life-long…

  8. Modeling Active Region Evolution - A New LWS TR and T Strategic Capability Model Suite

    NASA Technical Reports Server (NTRS)

    MacNeice, Peter

    2012-01-01

    In 2006 the LWS TR&T Program funded us to develop a strategic capability model of slowly evolving coronal active regions. In this poster we report on the overall design, and status of our new modeling suite. Our design features two coronal field models, a non-linear force free field model and a global 3D MHD code. The suite includes supporting tools and a user friendly GUI which will enable users to query the web for relevant magnetograms, download them, process them to synthesize a sequence of photospheric magnetograms and associated photospheric flow field which can then be applied to drive the coronal model innner boundary, run the coronal models and finally visualize the results.

  9. Aerodynamic Design Study of an Advanced Active Twist Rotor

    NASA Technical Reports Server (NTRS)

    Sekula, Martin K.; Wilbur, Matthew L.; Yeager, William T., Jr.

    2003-01-01

    An Advanced Active Twist Rotor (AATR) is currently being developed by the U.S. Army Vehicle Technology Directorate at NASA Langley Research Center. As a part of this effort, an analytical study was conducted to determine the impact of blade geometry on active-twist performance and, based on those findings, propose a candidate aerodynamic design for the AATR. The process began by creating a baseline design which combined the dynamic design of the original Active Twist Rotor and the aerodynamic design of a high lift rotor concept. The baseline model was used to conduct a series of parametric studies to examine the effect of linear blade twist and blade tip sweep, droop, and taper on active-twist performance. Rotor power requirements and hub vibration were also examined at flight conditions ranging from hover to advance ratio = 0.40. A total of 108 candidate designs were analyzed using the second-generation version of the Comprehensive Analytical Model of Rotorcraft Aerodynamics and Dynamics (CAMRAD II) code. The study concluded that the vibration reduction capabilities of a rotor utilizing controlled, strain-induced twisting are enhanced through the incorporation of blade tip sweep, droop, and taper into the blade design, while they are degraded by increasing the nose-down linear blade twist. Based on the analysis of rotor power, hub vibration, and active-twist response, a candidate aerodynamic design for the AATR consisting of a blade with approximately 10 degrees of linear blade twist and a blade tip design with 30 degree sweep, 10 degree droop, and 2.5:1 taper ratio over the outer five percent of the blade is proposed.

  10. Design and Analysis of Complex D-Regions in Reinforced Concrete Structures

    ERIC Educational Resources Information Center

    Yindeesuk, Sukit

    2009-01-01

    STM design provisions, such as those in Appendix A of ACI318-08, consist of rules for evaluating the capacity of the load-resisting truss that is idealized to carry the forces through the D-Region. These code rules were primarily derived from test data on simple D-Regions such as deep beams and corbels. However, these STM provisions are taken as…

  11. 76 FR 58533 - Powder River Regional Coal Team Activities; Notice of Public Meeting in Casper, WY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-21

    ... Bureau of Land Management Powder River Regional Coal Team Activities; Notice of Public Meeting in Casper... River Regional Coal Team (RCT) has scheduled a public meeting for October 26, 2011, to review coal management activities in the Powder River Coal Production Region. DATES: The RCT meeting will begin at 9...

  12. Multidisciplinary design optimization of mechatronic vehicles with active suspensions

    NASA Astrophysics Data System (ADS)

    He, Yuping; McPhee, John

    2005-05-01

    A multidisciplinary optimization method is applied to the design of mechatronic vehicles with active suspensions. The method is implemented in a GA-A'GEM-MATLAB simulation environment in such a way that the linear mechanical vehicle model is designed in a multibody dynamics software package, i.e. A'GEM, the controllers and estimators are constructed using linear quadratic Gaussian (LQG) method, and Kalman filter algorithm in Matlab, then the combined mechanical and control model is optimized simultaneously using a genetic algorithm (GA). The design variables include passive parameters and control parameters. In the numerical optimizations, both random and deterministic road inputs and both perfect measurement of full state variables and estimated limited state variables are considered. Optimization results show that the active suspension systems based on the multidisciplinary optimization method have better overall performance than those derived using conventional design methods with the LQG algorithm.

  13. The Limit of Magnetic-Shear Energy in Solar Active Regions

    NASA Technical Reports Server (NTRS)

    Moore, Ronald L.; Falconer, David A.; Sterling, Alphonse C.

    2013-01-01

    It has been found previously, by measuring from active ]region magnetograms a proxy of the free energy in the active region fs magnetic field, (1) that there is a sharp upper limit to the free energy the field can hold that increases with the amount of magnetic field in the active region, the active region fs magnetic flux content, and (2) that most active regions are near this limit when their field explodes in a CME/flare eruption. That is, explosive active regions are concentrated in a main ]sequence path bordering the free ]energy ]limit line in (flux content, free ]energy proxy) phase space. Here we present evidence that specifies the underlying magnetic condition that gives rise to the free ]energy limit and the accompanying main sequence of explosive active regions. Using a suitable free energy proxy measured from vector magnetograms of 44 active regions, we find evidence that (1) in active regions at and near their free ]energy limit, the ratio of magnetic ]shear free energy to the non ]free magnetic energy the potential field would have is of order 1 in the core field, the field rooted along the neutral line, and (2) this ratio is progressively less in active regions progressively farther below their free ]energy limit. Evidently, most active regions in which this core ]field energy ratio is much less than 1 cannot be triggered to explode; as this ratio approaches 1, most active regions become capable of exploding; and when this ratio is 1, most active regions are compelled to explode.

  14. The Limit of Magnetic-Shear Energy in Solar Active Regions

    NASA Technical Reports Server (NTRS)

    Moore, Ronald; Falconer, David; Sterling, Alphonse

    2012-01-01

    It has been found previously, by measuring from active-region magnetograms a proxy of the free energy in the active region's magnetic field, (1) that there is a sharp upper limit to the free energy the field can hold that increases with the amount of magnetic field in the active region, the active region's magnetic flux content, and (2) that most active regions are near this limit when their field explodes in a coronal mass ejection/flare eruption. That is, explosive active regions are concentrated in a main-sequence path bordering the free-energy-limit line in (flux content, free-energy proxy) phase space. Here, we present evidence that specifies the underlying magnetic condition that gives rise to the free-energy limit and the accompanying main sequence of explosive active regions. Using a suitable free-energy proxy measured from vector magnetograms of 44 active regions, we find evidence that (1) in active regions at and near their free-energy limit, the ratio of magnetic-shear free energy to the non-free magnetic energy the potential field would have is of the order of one in the core field, the field rooted along the neutral line, and (2) this ratio is progressively less in active regions progressively farther below their free-energy limit. Evidently, most active regions in which this core-field energy ratio is much less than one cannot be triggered to explode; as this ratio approaches one, most active regions become capable of exploding; and when this ratio is one, most active regions are compelled to explode.

  15. THE LIMIT OF MAGNETIC-SHEAR ENERGY IN SOLAR ACTIVE REGIONS

    SciTech Connect

    Moore, Ronald L.; Falconer, David A.; Sterling, Alphonse C.

    2012-05-01

    It has been found previously, by measuring from active-region magnetograms a proxy of the free energy in the active region's magnetic field, (1) that there is a sharp upper limit to the free energy the field can hold that increases with the amount of magnetic field in the active region, the active region's magnetic flux content, and (2) that most active regions are near this limit when their field explodes in a coronal mass ejection/flare eruption. That is, explosive active regions are concentrated in a main-sequence path bordering the free-energy-limit line in (flux content, free-energy proxy) phase space. Here, we present evidence that specifies the underlying magnetic condition that gives rise to the free-energy limit and the accompanying main sequence of explosive active regions. Using a suitable free-energy proxy measured from vector magnetograms of 44 active regions, we find evidence that (1) in active regions at and near their free-energy limit, the ratio of magnetic-shear free energy to the non-free magnetic energy the potential field would have is of the order of one in the core field, the field rooted along the neutral line, and (2) this ratio is progressively less in active regions progressively farther below their free-energy limit. Evidently, most active regions in which this core-field energy ratio is much less than one cannot be triggered to explode; as this ratio approaches one, most active regions become capable of exploding; and when this ratio is one, most active regions are compelled to explode.

  16. Layered shielding design for an active neutron interrogation system

    NASA Astrophysics Data System (ADS)

    Whetstone, Zachary D.; Kearfott, Kimberlee J.

    2016-08-01

    The use of source and detector shields in active neutron interrogation can improve detector signal. In simulations, a shielded detector with a source rotated π/3 rad relative to the opening decreased neutron flux roughly three orders of magnitude. Several realistic source and detector shield configurations were simulated. A layered design reduced neutron and secondary photon flux in the detector by approximately one order of magnitude for a deuterium-tritium source. The shield arrangement can be adapted for a portable, modular design.

  17. Gearbox design for uncertain load requirements using active robust optimization

    NASA Astrophysics Data System (ADS)

    Salomon, Shaul; Avigad, Gideon; Purshouse, Robin C.; Fleming, Peter J.

    2016-04-01

    Design and optimization of gear transmissions have been intensively studied, but surprisingly the robustness of the resulting optimal design to uncertain loads has never been considered. Active Robust (AR) optimization is a methodology to design products that attain robustness to uncertain or changing environmental conditions through adaptation. In this study the AR methodology is utilized to optimize the number of transmissions, as well as their gearing ratios, for an uncertain load demand. The problem is formulated as a bi-objective optimization problem where the objectives are to satisfy the load demand in the most energy efficient manner and to minimize production cost. The results show that this approach can find a set of robust designs, revealing a trade-off between energy efficiency and production cost. This can serve as a useful decision-making tool for the gearbox design process, as well as for other applications.

  18. Design of a High Gradient Quadrupole for the LHC Interaction Regions

    SciTech Connect

    Bossert, R.; Gourlay, S.A.; Heger, T.; Huang, Y.; Kerby, J.; Lamm, M.J.; Limon, P.J.; Mazur, P.O.; Nobrega, F.; Ozelis, J.P.; Sabbi, G.; Strait, J.; Zlobin, A.V.; Caspi, S.; Dell`orco, D.; McInturff, A.D.; Scanlan, R.M.; Van Oort, J.M.; Gupta, R.C.

    1997-03-01

    A collaboration of Fermilab, Lawrence Berkeley National Laboratory and Brookhaven National Laboratory is currently engaged in the design of a high gradient quadrupole suitable for use in the LHC interaction regions. The cold iron design incorporates a two-shell, cos2{theta} coil geometry with a 70 mm aperture. This paper summarizes the progress on a magnetic and mechanical design that meets the requirements of maximum gradient {>=}250 T/m, operation at 1.8K, high field quality and provision for adequate cooling in a high radiation environment.

  19. Application of the active camber morphing concept based on compliant structures to a regional aircraft

    NASA Astrophysics Data System (ADS)

    De Gaspari, Alessandro; Ricci, Sergio

    2014-04-01

    The present work addresses the optimal design of a morphing mechanism based on compliant structures used to implement the active camber morphing concept. The subject of the work is part of the FP7-NOVEMOR project (Novel Air Vehicle Configurations: From Fluttering Wings to Morphing Flight) which is one of the many projects from the seventh European Framework Programme. The implementation of active camber concept is based on the use of conformable morphing control surfaces. Aiming at the optimal design of such as morphing devices, two dedicated tools called PHORMA and SPHERA, respectively, are introduced. The definition of the optimal shape taking into account both aerodynamic and structural constraints is done by PHORMA. Then SPHERA, based on the load path approach codified by coupling a non linear beam solver to a genetic multi- objective optimizer, is adopted to generate the optimal internal structure able to produce, when loaded, the target optimal shape. The paper is mainly focused on the optimal design of the compliant structures starting from the optimal shape already available for a Reference Aircraft (RA) developed inside NOVEMOR project and representative of a typical regional jet capable to carry 113 PAX in a single economic class.

  20. Associations between Accelerometer-derived Physical Activity and Regional Adiposity in Young Men and Women

    PubMed Central

    Smith, H A; Storti, K L; Arena, VC; Kriska, A M; Gabriel, K K Pettee; Sutton-Tyrrell, K; Hames, K C; Conroy, M B

    2013-01-01

    Objective Empirical evidence supports an inverse relationship between physical activity (PA) and adiposity, but studies using detailed measures of both are scarce. We described the relationship between regional adiposity and accelerometer-derived PA in men and women. Design and Methods Cross-sectional analysis included 253 participants from a weight loss study limited to ages 20–45 years and BMI 25–39.9 kg/m2. PA data were collected with accelerometers and expressed as total accelerometer counts and average amount of time per day accumulated in different intensity levels (sedentary, light-, and moderate- to vigorous- intensity PA (MVPA)). Accumulation of time spent above 100 counts was expressed as total active time. Computed tomography (CT) was used to measure abdominal and adipose tissue (AT). Multivariate linear regression analyses were used to assess the relationship between regional adiposity (dependent variable) and the various PA levels (independent variable), and were executed separately for men and women, adjusting for wear time, age, race, education, and BMI. Results Among males light activity was inversely associated with total AT (β=−0.19; p=0.02) as well as visceral AT (VAT) (β=−0.30; p=0.03). Among females sedentary time was positively associated with VAT (β=0.11; p=0.04) and total active time was inversely associated with VAT (β=−0.12; p=0.04). Conclusions Findings from this study suggest that PA intensity level may influence regional adiposity differently in men and women. Additional research is needed in larger samples to clarify the difference in these associations by sex, create recommendations for the frequency, duration and intensity of PA needed to target fat deposits, and determine if these recommendations should differ by sex. PMID:23408709

  1. Designing and Building a Cardboard Chair: Children's Engineering at the TECA Eastern Regional Conference

    ERIC Educational Resources Information Center

    Linnell, Charles C.

    2007-01-01

    This article describes the 2006 Technology Education Collegiate Association (TECA) Eastern Regional elementary competition, wherein teams of technology education students from nine different universities designed and built cardboard chairs. The competition required the teams (four or five to a team) from universities up and down the East Coast to…

  2. Interaction-Region Design Options for a Linac-Ring LHeC

    SciTech Connect

    Zimmermann, Frank; Bettoni, Simona; Bruning, Oliver; Holzer, Bernhard; Russenschuck, Stephan; Schulte, Daniel; Tomas, Rogelio; Aksakal, Husnu; Appleby, Robert; Chattopadhyay, Swapan; Korostelev, Maxim; Ciftci, Abbas; Ciftci, Rena; Zengin, Kahraman; Dainton, John; Klein, Max; Eroglu, Emre; Tapan, Ilhan; Kostka, Peter; Litvinenko, Vladimir; Paoloni, Eugenio; /INFN, Pisa /INFN, Bologna /DESY /SLAC

    2012-06-21

    The interaction-region design for a linac-ring electron-proton collider based on the LHC ('LR-LHeC') poses numerous challenges related to collision scheme, synchrotron radiation, aperture, magnet technology, and optics. We report a first assessment and various options.

  3. Temperature performance of terahertz quantum-cascade lasers with resonant-phonon active-regions

    NASA Astrophysics Data System (ADS)

    Khanal, Sudeep; Zhao, Le; Reno, John L.; Kumar, Sushil

    2014-09-01

    Significant progress has recently been made toward improving the power output, beam quality and spectral characteristics of terahertz quantum cascade lasers (QCLs). However, the maximum operating temperature of the best-performing devices has become relatively stagnant and is in the range of 150-200 K for QCLs designed to emit in the frequency range of 2-4 THz. Such QCLs are primarily designed with resonant-phonon depopulation schemes. The requirement to cryogenically cool terahertz QCLs leads to stringent limitations on their use for various applications. Although significant advances have been made to model quantum transport in quantum cascade superlattices, the relative role of various electron transport mechanisms as a function of temperature is not clear. This article discusses temperature behavior of resonant-phonon terahertz QCLs with respect to a variety of active-region design schemes, and argues that precise understanding of high-temperature transport remains elusive for terahertz QCLs. The role of electron-phonon scattering, collisional-broadening, thermal leakage, and interface-roughness scattering towards the degradation of intersubband optical gain at higher temperatures is discussed for the popular terahertz QCL designs.

  4. An improved permanent magnet quadrupole design with larger good field region for high intensity proton linacs

    NASA Astrophysics Data System (ADS)

    Mathew, Jose V.; Rao, S. V. L. S.; Krishnagopal, S.; Singh, P.

    2013-11-01

    The Low Energy High Intensity Proton Accelerator (LEHIPA), being developed at the Bhabha Atomic Research Centre (BARC) will produce a 20 MeV, 30 mA, continuous wave (CW) proton beam. At these low velocities, space-charge forces dominate, and could lead to larger beam sizes and beam halos. Hence in the design of the focusing lattice of the LEHIPA drift tube linac (DTL) using permanent magnet quadrupoles (PMQs), a larger good field region is preferred. Here we study, using the two dimensional (2D) and three dimensional (3D) simulation codes PANDIRA and RADIA, four different types of cylindrical PMQ designs: 16-segment trapezoidal Halbach configuration, bullet-nosed geometry and 8- and 16-segment rectangular geometries. The trapezoidal Halbach geometry is used in a variety of accelerators since it provides very high field gradients in small bores, while the bullet-nosed geometry, which is a combination of the trapezoidal and rectangular designs, is used in some DTLs. This study shows that a larger good field region is possible in the 16-segment rectangular design as compared to the Halbach and bullet-nosed designs, making it more attractive for high-intensity proton linacs. An improvement in good-field region by ˜16% over the Halbach design is obtained in the optimized 16-segment rectangular design, although the field gradient is lower by ˜20%. Tolerance studies show that the rectangular segment PMQ design is substantially less sensitive to the easy axis orientation errors and hence will be a better choice for DTLs.

  5. Antibody Constant Region Peptides Can Display Immunomodulatory Activity through Activation of the Dectin-1 Signalling Pathway

    PubMed Central

    Cenci, Elio; Monari, Claudia; Magliani, Walter; Ciociola, Tecla; Conti, Stefania; Gatti, Rita; Bistoni, Francesco; Polonelli, Luciano; Vecchiarelli, Anna

    2012-01-01

    We previously reported that a synthetic peptide with sequence identical to a CDR of a mouse monoclonal antibody specific for difucosyl human blood group A exerted an immunomodulatory activity on murine macrophages. It was therapeutic against systemic candidiasis without possessing direct candidacidal properties. Here we demonstrate that a selected peptide, N10K, putatively deriving from the enzymatic cleavage of the constant region (Fc) of human IgG1, is able to induce IL-6 secretion and pIkB-α activation. More importantly, it causes an up-regulation of Dectin-1 expression. This leads to an increased activation of β-glucan-induced pSyk, CARD9 and pIkB-α, and an increase in the production of pro-inflammatory cytokines such as IL-6, IL-12, IL-1β and TNF-α. The increased activation of this pathway coincides with an augmented phagocytosis of non opsonized Candida albicans cells by monocytes. The findings suggest that some Fc-peptides, potentially deriving from the proteolysis of immunoglobulins, may cause an unexpected immunoregulation in a way reminiscent of innate immunity molecules. PMID:22952831

  6. LOW-LATITUDE CORONAL HOLES, DECAYING ACTIVE REGIONS, AND GLOBAL CORONAL MAGNETIC STRUCTURE

    SciTech Connect

    Petrie, G. J. D.; Haislmaier, K. J.

    2013-10-01

    We study the relationship between decaying active-region magnetic fields, coronal holes, and the global coronal magnetic structure using Global Oscillations Network Group synoptic magnetograms, Solar TErrestrial RElations Observatory extreme-ultraviolet synoptic maps, and coronal potential-field source-surface models. We analyze 14 decaying regions and associated coronal holes occurring between early 2007 and late 2010, 4 from cycle 23 and 10 from cycle 24. We investigate the relationship between asymmetries in active regions' positive and negative magnetic intensities, asymmetric magnetic decay rates, flux imbalances, global field structure, and coronal hole formation. Whereas new emerging active regions caused changes in the large-scale coronal field, the coronal fields of the 14 decaying active regions only opened under the condition that the global coronal structure remained almost unchanged. This was because the dominant slowly varying, low-order multipoles prevented opposing-polarity fields from opening and the remnant active-region flux preserved the regions' low-order multipole moments long after the regions had decayed. Thus, the polarity of each coronal hole necessarily matched the polar field on the side of the streamer belt where the corresponding active region decayed. For magnetically isolated active regions initially located within the streamer belt, the more intense polarity generally survived to form the hole. For non-isolated regions, flux imbalance and topological asymmetry prompted the opposite to occur in some cases.

  7. A New Interaction Region Design for the Super-B Factory

    SciTech Connect

    Sullivan, Michael; Bertsche, Kirk; Bettoni, Simona; Paoloni, Eugenio; Raimondi, Pantaleo; Vobly, Pavel; /Novosibirsk, IYF

    2012-07-06

    A final focus magnet design that uses super-ferric magnets is introduced for the SuperB interaction region. The baseline design has air-core super-conducting quadrupoles. This idea instead uses super-conducting wire in an iron yoke. The iron is in the shape of a Panofsky quadrupole and this allows two quadrupoles to be side-by-side with no intervening iron as long as the gradients of the two quads are equal. This feature allows us to move in as close as possible to the collision point and minimize the beta functions in the interaction region. The superferric design has advantages as well as drawbacks and we will discuss these in the paper.

  8. PROGRESS ON THE INTERACTION REGION DESIGN AND DETECTOR INTEGRATION AT JLAB'S MEIC

    SciTech Connect

    Morozov, Vasiliy; Brindza, Paul; Camsonne, Alexandre; Derbenev, Yaroslav; Ent, Rolf; Gaskell, David; Lin, Fanglei; Nadel-Turonski, Pawel; Ungaro, Maurizio; Zhang, Yuhong; Hyde, Charles; Park, Kijun; Sullivan, Michael; Zhao, Zhiwen

    2014-07-01

    One of the unique features of JLab's Medium-energy Electron-Ion Collider (MEIC) is a full-acceptance detector with a dedicated, small-angle, high-resolution detection system, capable of covering a wide range of momenta (and charge-to-mass ratios) with respect to the original ion beam to enable access to new physics. We present an interaction region design developed with close integration of the detection and beam dynamical aspects. The dynamical aspect of the design rests on a symmetry-based concept for compensation of non-linear effects. The optics and geometry have been optimized to accommodate the detection requirements and to ensure the interaction region's modularity for ease of integration into the collider ring lattices. As a result, the design offers an excellent detector performance combined with the necessary provisions for non-linear dynamical optimization.

  9. A Tale of Two Super-Active Active Regions: On the Magnetic Origin of Flares and CMEs

    NASA Astrophysics Data System (ADS)

    Zhang, Jie; Dhakal, Suman; Chintzoglou, Georgios

    2015-04-01

    From a comparative study of two super-active active regions, we find that the magnetic origin of CMEs is different from that of flares. NOAA AR 12192 is one of the largest active regions in the recorded history with a sunspot number of 66 and area of 2410 millonths. During its passage through the front disk from Oct. 14-30, 2014, the active region produced 93 C-class, 30 M-class and 6 X-class flares. However, all six X-class flares are confined; in other words, none of them are associated with CMEs; most other flares are also confined. This behavior of low-CME production rate for such as a super active region is rather peculiar, given the usual hand-on-hand occurrence of CMEs with flares. To further strengthen this point, we also investigated the super-active NOAA AR 11429, which had a sunspot number of 28 and area of 1270 millionths. During its passage from March 02-17, 2012, the active region produced 47 C-class, 15 M-class and 3 X-class flares. In this active region, all three X-class flares were accompanied by CMEs, and the same for most M-class flares. Given the relative sizes of the two active regions, the production rates of flares are comparable. But the CME production rates are not. Through a careful study of the magnetic configuration on the surface and the extrapolated magnetic field in the corona, we argue that the generation of flares largely depends on the amount of free energy in the active region. On the other hand, the generation of CMEs largely depends on the complexity, such as measured by magnetic helicity. In particular, we argue that the high CME generation rate in the smaller active region is caused by the emergence and continuous generation of magnetic flux ropes in the region.

  10. Design of multitarget activity landscapes that capture hierarchical activity cliff distributions.

    PubMed

    Dimova, Dilyana; Wawer, Mathias; Wassermann, Anne Mai; Bajorath, Jürgen

    2011-02-28

    An activity landscape model of a compound data set can be rationalized as a graphical representation that integrates molecular similarity and potency relationships. Activity landscape representations of different design are utilized to aid in the analysis of structure-activity relationships and the selection of informative compounds. Activity landscape models reported thus far focus on a single target (i.e., a single biological activity) or at most two targets, giving rise to selectivity landscapes. For compounds active against more than two targets, landscapes representing multitarget activities are difficult to conceptualize and have not yet been reported. Herein, we present a first activity landscape design that integrates compound potency relationships across multiple targets in a formally consistent manner. These multitarget activity landscapes are based on a general activity cliff classification scheme and are visualized in graph representations, where activity cliffs are represented as edges. Furthermore, the contributions of individual compounds to structure-activity relationship discontinuity across multiple targets are monitored. The methodology has been applied to derive multitarget activity landscapes for compound data sets active against different target families. The resulting landscapes identify single-, dual-, and triple-target activity cliffs and reveal the presence of hierarchical cliff distributions. From these multitarget activity landscapes, compounds forming complex activity cliffs can be readily selected.

  11. Using Fall to Design Activities: In the Classroom.

    ERIC Educational Resources Information Center

    Grambo, Gregory

    1994-01-01

    Examples of fall activities to bring the natural world into the classroom are offered including conducting a simple chromatography experiment on leaves, correlating number of seeds with the lines on pumpkins, planting colored corn kernels, and designing and making scarecrows. (DB)

  12. Designing the Perfect Plant: Activities to Investigate Plant Ecology

    ERIC Educational Resources Information Center

    Lehnhoff, Erik; Woolbaugh, Walt; Rew, Lisa

    2008-01-01

    Plant ecology is an important subject that often receives little attention in middle school, as more time during science classes is devoted to plant biology. Therefore, the authors have developed a series of activities, including a card game--Designing the Perfect Plant--to introduce student's to plant ecology and the ecological trade offs…

  13. Active flutter suppression - Control system design and experimental validation

    NASA Technical Reports Server (NTRS)

    Waszak, Martin R.; Srinathkumar, S.

    1991-01-01

    The synthesis and experimental validation of an active flutter suppression controller for the Active Flexible Wing wind-tunnel model is presented. The design is accomplished with traditional root locus and Nyquist methods using interactive computer graphics tools and with extensive use of simulation-based analysis. The design approach uses a fundamental understanding of the flutter mechanism to formulate a simple controller structure to meet stringent design specifications. Experimentally, the flutter suppression controller succeeded in simultaneous suppression of two flutter modes, significantly increasing the flutter dynamic pressure despite errors in flutter dynamic pressure and flutter frequency in the mathematical model. The flutter suppression controller was also successfully operated in combination with a roll maneuver controller to perform flutter suppression during rapid rolling maneuvers.

  14. Seismic activity monitoring in the Izvorul Muntelui dam region

    NASA Astrophysics Data System (ADS)

    Borleanu, Felix; Otilia Placinta, Anca; Popa, Mihaela; Adelin Moldovan, Iren; Popescu, Emilia

    2016-04-01

    Earthquakes occurrences near the artificial water reservoirs are caused by stress variation due to the weight of water, weakness of fractures or faults and increasing of pore pressure in crustal rocks. In the present study we aim to investigate how Izvorul Muntelui dam, located in the Eastern Carpathians influences local seismicity. For this purpose we selected from the seismic bulletins computed within National Data Center of National Institute for Earth Physics, Romania, crustal events occurred between 984 and 2015 in a range of 0.3 deg around the artificial lake. Subsequently to improve the seismic monitoring of the region we applied a cross-correlation detector on the continuous recordings of Bicaz (BIZ) seismic stations. Besides the tectonic events we detected sources within this region that periodically generate artificial evens. We couldn't emphasize the existence of a direct correlation between the water level variations and natural seismicity of the investigated area.

  15. Optical design and active optics methods in astronomy

    NASA Astrophysics Data System (ADS)

    Lemaitre, Gerard R.

    2013-03-01

    Optical designs for astronomy involve implementation of active optics and adaptive optics from X-ray to the infrared. Developments and results of active optics methods for telescopes, spectrographs and coronagraph planet finders are presented. The high accuracy and remarkable smoothness of surfaces generated by active optics methods also allow elaborating new optical design types with high aspheric and/or non-axisymmetric surfaces. Depending on the goal and performance requested for a deformable optical surface analytical investigations are carried out with one of the various facets of elasticity theory: small deformation thin plate theory, large deformation thin plate theory, shallow spherical shell theory, weakly conical shell theory. The resulting thickness distribution and associated bending force boundaries can be refined further with finite element analysis.

  16. Regional systems of care demonstration project: Mission: Lifeline STEMI Systems Accelerator: design and methodology.

    PubMed

    Bagai, Akshay; Al-Khalidi, Hussein R; Sherwood, Matthew W; Muñoz, Daniel; Roettig, Mayme L; Jollis, James G; Granger, Christopher B

    2014-01-01

    ST-segment elevation myocardial infarction (STEMI) systems of care have been associated with significant improvement in use and timeliness of reperfusion. Consequently, national guidelines recommend that each community should develop a regional STEMI care system. However, significant barriers continue to impede widespread establishment of regional STEMI care systems in the United States. We designed the Regional Systems of Care Demonstration Project: Mission: Lifeline STEMI Systems Accelerator, a national educational outcome research study in collaboration with the American Heart Association, to comprehensively accelerate the implementation of STEMI care systems in 17 major metropolitan regions encompassing >1,500 emergency medical service agencies and 450 hospitals across the United States. The goals of the program are to identify regional gaps, barriers, and inefficiencies in STEMI care and to devise strategies to implement proven recommendations to enhance the quality and consistency of care. The study interventions, facilitated by national faculty with expertise in regional STEMI system organization in partnership with American Heart Association representatives, draw upon specific resources with proven past effectiveness in augmenting regional organization. These include bringing together leading regional health care providers and institutions to establish common commitment to STEMI care improvement, developing consensus-based standardized protocols in accordance with national professional guidelines to address local needs, and collecting and regularly reviewing regional data to identify areas for improvement. Interventions focus on each component of the reperfusion process: the emergency medical service, the emergency department, the catheterization laboratory, and inter-hospital transfer. The impact of regionalization of STEMI care on clinical outcomes will be evaluated.

  17. Automatic Tracking of Active Regions and Detection of Solar Flares in Solar EUV Images

    NASA Astrophysics Data System (ADS)

    Caballero, C.; Aranda, M. C.

    2014-05-01

    Solar catalogs are frequently handmade by experts using a manual approach or semi-automated approach. The appearance of new tools is very useful because the work is automated. Nowadays it is impossible to produce solar catalogs using these methods, because of the emergence of new spacecraft that provide a huge amount of information. In this article an automated system for detecting and tracking active regions and solar flares throughout their evolution using the Extreme UV Imaging Telescope (EIT) on the Solar and Heliospheric Observatory (SOHO) spacecraft is presented. The system is quite complex and consists of different phases: i) acquisition and preprocessing; ii) segmentation of regions of interest; iii) clustering of these regions to form candidate active regions which can become active regions; iv) tracking of active regions; v) detection of solar flares. This article describes all phases, but focuses on the phases of tracking and detection of active regions and solar flares. The system relies on consecutive solar images using a rotation law to track the active regions. Also, graphs of the evolution of a region and solar evolution are presented to detect solar flares. The procedure developed has been tested on 3500 full-disk solar images (corresponding to 35 days) taken from the spacecraft. More than 75 % of the active regions are tracked and more than 85 % of the solar flares are detected.

  18. Rain rate intensity model for communication link design across the Indian region

    NASA Astrophysics Data System (ADS)

    Kilaru, Aravind; Kotamraju, Sarat K.; Avlonitis, Nicholas; Sri Kavya, K. Ch.

    2016-07-01

    A study on rain statistical parameters such as one minute rain intensity, possible number of minute occurrences with respective percentage of time in a year has been evaluated for the purpose of communication link design at Ka, Q, V bands as well as at Free-Space Optical communication links (FSO). To understand possible outage period of a communication links due to rainfall and to investigate rainfall pattern, Automatic Weather Station (AWS) rainfall data is analysed due its ample presence across India. The climates of the examined AWS regions vary from desert to cold climate, heavy rainfall to variable rainfall regions, cyclone effective regions, mountain and coastal regions. In this way a complete and unbiased picture of the rainfall statistics for Indian region is evaluated. The analysed AWS data gives insight into yearly accumulated rainfall, maximum hourly accumulated rainfall, mean hourly accumulated rainfall, number of rainy days and number of rainy hours from 668 AWS locations. Using probability density function the one minute rainfall measurements at KL University is integrated with AWS measurements for estimating number of rain occurrences in terms of one minute rain intensity for annual rainfall accumulated between 100 mm and 5000 mm to give an insight into possible one minute accumulation pattern in an hour for comprehensive analysis of rainfall influence on a communication link for design engineers. So that low availability communications links at higher frequencies can be transformed into a reliable and economically feasible communication links for implementing High Throughput Services (HTS).

  19. ACHROMATIC LOW-BETA INTERACTION REGION DESIGN FOR AN ELECTRON-ION COLLIDER

    SciTech Connect

    Vasiliy Morozov, Yaroslav Derbenev

    2011-09-01

    An achromatic Interaction Region (IR) design concept is presented with an emphasis on its application at an electron-ion collider. A specially-designed symmetric Chromaticity Compensation Block (CCB) induces an angle spread in the passing beam such that it cancels the chromatic kick of the final focusing quadrupoles. Two such CCB's placed symmetrically around an interaction point (IP) allow simultaneous compensation of the 1st-order chromaticities and chromatic beam smear at the IP without inducing significant 2nd-order aberrations. Special attention is paid to the difference in the electron and ion IR design requirements. We discuss geometric matching of the electron and ion IR footprints. We investigate limitations on the momentum acceptance in this IR design.

  20. Wireless design of a multisensor system for physical activity monitoring.

    PubMed

    Mo, Lingfei; Liu, Shaopeng; Gao, Robert X; John, Dinesh; Staudenmayer, John W; Freedson, Patty S

    2012-11-01

    Real-time monitoring of human physical activity (PA) is important for assessing the intensity of activity and exposure to environmental pollutions. A wireless wearable multisenor integrated measurement system (WIMS) has been designed for real-time measurement of the energy expenditure and breathing volume of human subjects under free-living conditions. To address challenges posted by the limited battery life and data synchronization requirement among multiple sensors in the system, the ZigBee communication platform has been explored for energy-efficient design. Two algorithms have been developed (multiData packaging and slot-data-synchronization) and coded into a microcontroller (MCU)-based sensor circuitry for real-time control of wireless data communication. Experiments have shown that the design enables continued operation of the wearable system for up to 68 h, with the maximum error for data synchronization among the various sensor nodes (SNs) being less than 24 ms. Experiment under free-living conditions have shown that the WIMS is able to correctly recognize the activity intensity level 86% of the time. The results demonstrate the effectiveness of the energy-efficient wireless design for human PA monitoring.

  1. Synthetic Physical Interactions Map Kinetochore-Checkpoint Activation Regions

    PubMed Central

    Ólafsson, Guðjón; Thorpe, Peter H.

    2016-01-01

    The spindle assembly checkpoint (SAC) is a key mechanism to regulate the timing of mitosis and ensure that chromosomes are correctly segregated to daughter cells. The recruitment of the Mad1 and Mad2 proteins to the kinetochore is normally necessary for SAC activation. This recruitment is coordinated by the SAC kinase Mps1, which phosphorylates residues at the kinetochore to facilitate binding of Bub1, Bub3, Mad1, and Mad2. There is evidence that the essential function of Mps1 is to direct recruitment of Mad1/2. To test this model, we have systematically recruited Mad1, Mad2, and Mps1 to most proteins in the yeast kinetochore, and find that, while Mps1 is sufficient for checkpoint activation, recruitment of either Mad1 or Mad2 is not. These data indicate an important role for Mps1 phosphorylation in SAC activation, beyond the direct recruitment of Mad1 and Mad2. PMID:27280788

  2. New design deforming controlling system of the active stressed lap

    NASA Astrophysics Data System (ADS)

    Ying, Li; Wang, Daxing

    2008-07-01

    A 450mm diameter active stressed lap has been developed in NIAOT by 2003. We design a new lap in 2007. This paper puts on emphases on introducing the new deforming control system of the lap. Aiming at the control characteristic of the lap, a new kind of digital deforming controller is designed. The controller consists of 3 parts: computer signal disposing, motor driving and force sensor signal disposing. Intelligent numeral PID method is applied in the controller instead of traditional PID. In the end, the result of new deformation are given.

  3. Magnetic field configuration in a flaring active region

    NASA Astrophysics Data System (ADS)

    Palacios, J.; Balmaceda, L. A.; Vieira, L. E.

    2015-10-01

    The Helioseismic and Magnetic Imager (HMI) on board the Solar Dynamics Observatory (SDO) provides continuous monitoring of the Sun's vector magnetic field through full-disk photospheric data with both high cadence and high spatial resolution. Here we investigate the evolution of AR 11249 from March 6 to March 7, 2012. We make use of HMI Stokes imaging, SDO/SHARPs, the HMI magnetic field line-of-sight (LOS) maps and the transverse components of the magnetic field as well as LOS velocity maps in order to detect regions with significant flux emergence and/or cancellation. In addition, we apply the Local Correlation Tracking (LCT) technique to the total and signed magnetic flux data and derive maps of horizontal velocity. From this analysis, we were able to pinpoint localized shear regions (and a shear channel) where penumbrae and pore formation areas, with strong linear polarization signals, are stretched and squeezed, showing also important downflows and upflows. We have also utilized Hinode/SP data and compared them to the HMI-SHARPs and the HMI-Stokes spectrograms. The aforementioned shear channel seems to correspond well with the X-class flare main channel of March 7 2012, as observed in AIA/SDO 171, 304 and 1600 Å.

  4. Time course of regional brain activity accompanying auditory verbal hallucinations in schizophrenia

    PubMed Central

    Hoffman, Ralph E.; Pittman, Brian; Constable, R. Todd; Bhagwagar, Zubin; Hampson, Michelle

    2011-01-01

    Background The pathophysiology of auditory verbal hallucinations remains poorly understood. Aims To characterise the time course of regional brain activity leading to auditory verbal hallucinations. Method During functional magnetic resonance imaging, 11 patients with schizophrenia or schizoaffective disorder signalled auditory verbal hallucination events by pressing a button. To control for effects of motor behaviour, regional activity associated with hallucination events was scaled against corresponding activity arising from random button-presses produced by 10 patients who did not experience hallucinations. Results Immediately prior to the hallucinations, motor-adjusted activity in the left inferior frontal gyrus was significantly greater than corresponding activity in the right inferior frontal gyrus. In contrast, motor-adjusted activity in a right posterior temporal region overshadowed corresponding activity in the left homologous temporal region. Robustly elevated motor-adjusted activity in the left temporal region associated with auditory verbal hallucinations was also detected, but only subsequent to hallucination events. At the earliest time shift studied, the correlation between left inferior frontal gyrus and right temporal activity was significantly higher for the hallucination group compared with non-hallucinating patients. Conclusions Findings suggest that heightened functional coupling between the left inferior frontal gyrus and right temporal regions leads to coactivation in these speech processing regions that is hallucinogenic. Delayed left temporal activation may reflect impaired corollary discharge contributing to source misattribution of resulting verbal images. PMID:21972276

  5. Evolution of a regional health-care information system--the design phase.

    PubMed

    Balkányi, L; Magyar, G; Lakner, G; Orosz, E

    1997-01-01

    In 1996 a program of the Soros Foundation was launched to study a regional health care inodel Main stake holders of health care financing and providing in three counties in South-Western Hungary found the idea appealing and the Soros Model Region Program was started. This paper outlines the activity of the second sub-project of the model region program: the development of a regional health care information system. The build-up of a data and knowledge base serving the differing needs of mentioned goals is based on international standards. Availability and user involvement is based on different media for presenting the information as printed publications, CD-ROM data bases and World Wide Web availability. A congruency and coherency principle is maintained by a unified data model used for different purposes and a planned unified communication protocol among all participants in the model region program. Studies regarding health care status, economics and financing on regional level show that a better fitting health care services profile and a more flexible resource management might be achieved based on the mentioned regionality principle.

  6. Gradual tolerance of metabolic activity is produced in mesolimbic regions by chronic cocaine treatment, while subsequent cocaine challenge activates extrapyramidal regions of rat brain.

    PubMed

    Hammer, R P; Cooke, E S

    1994-07-01

    Acute administration of cocaine is known to enhance extracellular dopamine levels in the striatum and to activate immediate-early gene expression in striatal neurons. Regional cerebral metabolic rate for glucose (rCMRglc) reportedly increases in extrapyramidal and mesolimbic brain regions in response to acute cocaine treatment. However, chronic administration attenuates the cocaine-induced enhancement of regional dopamine response and the induction of immediate-early gene expression in these regions. Chronic treatment also produces tolerance to cocaine's reinforcing effects. Thus, differential responses to cocaine occur with increasing length of treatment. Therefore, we examined the time course of effects of repeated daily cocaine treatment on rCMRglc in rat brain. Acute administration of 10 mg/kg cocaine slightly increased rCMRglc in mesolimbic and extrapyramidal regions. However, no significant effects were observed until more than 7 d of treatment, whereupon rCMRglc was reduced compared to saline treatment in the infralimbic portion of the medial prefrontal cortex, nucleus accumbens, olfactory tubercle, habenula, amygdala, and a few other brain regions. In contrast, after 13 d of 10 mg/kg cocaine treatment, challenge with 30 mg/kg cocaine increased rCMRglc in the striatum, globus pallidus, entopeduncular nucleus, subthalamus, substantia nigra pars reticulata, and a few other regions without affecting limbic or mesolimbic regions. Thus, repeated daily treatment with a low dose of cocaine gradually decreased metabolic activity particularly in mesolimbic regions. Subsequent treatment with a higher dose produced metabolic activation mostly in extrapyramidal regions. This effect of chronic treatment could represent tolerance to the initial metabolic response, which can be replicated thereafter but only by increasing the drug dose. These results suggest that tolerance to the metabolic effects of cocaine in selective mesolimbic circuits may contribute to the

  7. Knowledge Discovery in Multidisciplinary Design Space for Regional-Jet Wings Using Data Mining

    NASA Astrophysics Data System (ADS)

    Chiba, Kazuhisa; Jeong, Shinkyu; Obayashi, Shigeru

    Data mining is an important facet of solving multi-objective optimization problems. In the present study, two data mining techniques were applied to a large-scale, real-world multidisciplinary design optimization (MDO) problem to provide knowledge regarding the design space. The use of MDO in the aerodynamics, structure, and aeroelasticity of a regional-jet wing was carried out using high-fidelity evaluation models with an adaptive range multi-objective genetic algorithm. As a result, nine non-dominated solutions were generated and used for tradeoff analysis of three objectives. All solutions evaluated during the evolution were analyzed for the influence of design variables using a self-organizing map (SOM) and a functional analysis of variance (ANOVA) to extract key features of the design space. As SOM and ANOVA compensate for respective disadvantages, the design knowledge could be obtained more clearly by combinating them. Although the MDO results showed inverted gull-wings as non-dominated solutions, one of the key features found by data mining was a non-gull wing geometry. When this knowledge was applied to one optimum solution, the resulting design was found to have better performance compared with the original geometry designed in the conventional manner.

  8. Knowledge Discovery for Transonic Regional-Jet Wing through Multidisciplinary Design Exploration

    NASA Astrophysics Data System (ADS)

    Chiba, Kazuhisa; Obayashi, Shigeru; Morino, Hiroyuki

    Data mining is an important facet of solving multi-objective optimization problem. Because it is one of the effective manner to discover the design knowledge in the multi-objective optimization problem which obtains large data. In the present study, data mining has been performed for a large-scale and real-world multidisciplinary design optimization (MDO) to provide knowledge regarding the design space. The MDO among aerodynamics, structures, and aeroelasticity of the regional-jet wing was carried out using high-fidelity evaluation models on the adaptive range multi-objective genetic algorithm. As a result, nine non-dominated solutions were generated and used for tradeoff analysis among three objectives. All solutions evaluated during the evolution were analyzed for the tradeoffs and influence of design variables using a self-organizing map to extract key features of the design space. Although the MDO results showed the inverted gull-wings as non-dominated solutions, one of the key features found by data mining was the non-gull wing geometry. When this knowledge was applied to one optimum solution, the resulting design was found to have better performance compared with the original geometry designed in the conventional manner.

  9. Program design for San Francisco Bay Region environment and resources planning study

    USGS Publications Warehouse

    ,

    1971-01-01

    The "Program Design" for the San Francisco Bay Region Environment and Resources Planning Study represents a refinement, elaboration, and extension of the plans which formed the basis for the cooperative program between the Department of the Interior, Geological Survey, and the Department of Housing and Urban Development, Office of Research and Technology, formally recognized in the Letter of Agreement of October 24, 1969, and begun January 1, 1970. From the first, the study was recognized as an experimental pilot study, and new developments in the state-of-the-art in the earth sciences and in urban and regional planning were recognized as necessary. Indeed, the development of a suitable structure for such a program was considered one of the important parts of the experiment. Consequently, one of the stated goals of the Letter of Agreement was to produce a Program Design.

  10. Design and fabrication of an optimum peripheral region for low gain avalanche detectors

    NASA Astrophysics Data System (ADS)

    Fernández-Martínez, Pablo; Flores, D.; Hidalgo, S.; Greco, V.; Merlos, A.; Pellegrini, G.; Quirion, D.

    2016-06-01

    Low Gain Avalanche Detectors (LGAD) represent a remarkable advance in high energy particle detection, since they provide a moderate increase (gain ~10) of the collected charge, thus leading to a notable improvement of the signal-to-noise ratio, which largely extends the possible application of Silicon detectors beyond their present working field. The optimum detection performance requires a careful implementation of the multiplication junction, in order to obtain the desired gain on the read out signal, but also a proper design of the edge termination and the peripheral region, which prevents the LGAD detectors from premature breakdown and large leakage current. This work deals with the critical technological aspects required to optimize the LGAD structure. The impact of several design strategies for the device periphery is evaluated with the aid of TCAD simulations, and compared with the experimental results obtained from the first LGAD prototypes fabricated at the IMB-CNM clean room. Solutions for the peripheral region improvement are also provided.

  11. Alpha2A adrenergic receptor activation inhibits epileptiform activity in the rat hippocampal CA3 region.

    PubMed

    Jurgens, Chris W D; Hammad, Hana M; Lichter, Jessica A; Boese, Sarah J; Nelson, Brian W; Goldenstein, Brianna L; Davis, Kylie L; Xu, Ke; Hillman, Kristin L; Porter, James E; Doze, Van A

    2007-06-01

    Norepinephrine has potent antiepileptic properties, the pharmacology of which is unclear. Under conditions in which GABAergic inhibition is blocked, norepinephrine reduces hippocampal cornu ammonis 3 (CA3) epileptiform activity through alpha(2) adrenergic receptor (AR) activation on pyramidal cells. In this study, we investigated which alpha(2)AR subtype(s) mediates this effect. First, alpha(2)AR genomic expression patterns of 25 rat CA3 pyramidal cells were determined using real-time single-cell reverse transcription-polymerase chain reaction, demonstrating that 12 cells expressed alpha(2A)AR transcript; 3 of the 12 cells additionally expressed mRNA for alpha(2C)AR subtype and no cells possessing alpha(2B)AR mRNA. Hippocampal CA3 epileptiform activity was then examined using field potential recordings in brain slices. The selective alphaAR agonist 6-fluoronorepinephrine caused a reduction of CA3 epileptiform activity, as measured by decreased frequency of spontaneous epileptiform bursts. In the presence of betaAR blockade, concentration-response curves for AR agonists suggest that an alpha(2)AR mediates this response, as the rank order of potency was 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine (UK-14304) >or= epinephrine >6-fluoronorepinephrine > norepinephrine > phenylephrine. Finally, equilibrium dissociation constants (K(b)) of selective alphaAR antagonists were functionally determined to confirm the specific alpha(2)AR subtype inhibiting CA3 epileptiform activity. Apparent K(b) values calculated for atipamezole (1.7 nM), MK-912 (4.8 nM), BRL-44408 (15 nM), yohimbine (63 nM), ARC-239 (540 nM), prazosin (4900 nM), and terazosin (5000 nM) correlated best with affinities previously determined for the alpha(2A)AR subtype (r = 0.99, slope = 1.0). These results suggest that, under conditions of impaired GABAergic inhibition, activation of alpha(2A)ARs is primarily responsible for the antiepileptic actions of norepinephrine in the rat hippocampal CA3

  12. High resolution ALMA observations of dense molecular medium in the central regions of active galaxies

    NASA Astrophysics Data System (ADS)

    Kohno, Kotaro

    2015-08-01

    I will present recent ALMA results on the dense molecular gas in the central regions of local active galaxies, including NGC 1068, NGC 1097, and NGC 7469, hosting both AGN and circumnuclear starburst regions. Impact of X-ray radiation, outflows, and shocks from active nuclei on the physical and chemical properties of the surrouding dense molecular medium will be discussed.

  13. The Atlantic Canada-New England Region and Environment. A Learning Activity Packet.

    ERIC Educational Resources Information Center

    Maine Univ., Orono. New England - Atlantic Provinces - Quebec Center.

    In this Learning Activity Packet (LAP) students examine the geographic and ecological bases of the Eastern international region. The overall objective of activities is to help students comprehend the man-earth relationship concept. By studying this familiar relevant region students gain geographic knowledge and skills applicable to other areas.…

  14. 50 CFR 216.240 - Specified activity and specified geographical region.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Active Sonar Training (AFAST) § 216.240 Specified activity and specified geographical region. (a... Navy is only authorized if it occurs incidental to the use of the following mid-frequency active sonar (MFAS) sources, high frequency active sonar (HFAS) sources, explosive sonobuoys, or similar sources,...

  15. 50 CFR 216.240 - Specified activity and specified geographical region.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Active Sonar Training (AFAST) § 216.240 Specified activity and specified geographical region. (a... Navy is only authorized if it occurs incidental to the use of the following mid-frequency active sonar (MFAS) sources, high frequency active sonar (HFAS) sources, explosive sonobuoys, or similar sources,...

  16. 50 CFR 216.240 - Specified activity and specified geographical region.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Active Sonar Training (AFAST) § 216.240 Specified activity and specified geographical region. (a... Navy is only authorized if it occurs incidental to the use of the following mid-frequency active sonar (MFAS) sources, high frequency active sonar (HFAS) sources, explosive sonobuoys, or similar sources,...

  17. Designing an Energy Drink: High School Students Learn Design and Marketing Skills in This Activity

    ERIC Educational Resources Information Center

    Martin, Doug

    2008-01-01

    A decade ago, energy drinks were almost nonexistent in the United States, but in the past five years they've become wildly popular. In fact, the $3.4 billion energy-drink market is expected to double this year alone, and the younger generation is the market targeted by manufacturers. This article presents an energy-drink designing activity. This…

  18. Fashion Design: Designing a Learner-Active, Multi-Level High School Course

    ERIC Educational Resources Information Center

    Nelson, Diane

    2009-01-01

    A high school fashion design teacher has much in common with the ringmaster of a three-ring circus. The challenges of teaching a hands-on course are to facilitate the entire class and to meet the needs of individual students. When teaching family and consumer sciences, the goal is to have a learner-active classroom. Revamping the high school's…

  19. Earthquake Model of the Middle East (EMME) Project: Active Fault Database for the Middle East Region

    NASA Astrophysics Data System (ADS)

    Gülen, L.; Wp2 Team

    2010-12-01

    The Earthquake Model of the Middle East (EMME) Project is a regional project of the umbrella GEM (Global Earthquake Model) project (http://www.emme-gem.org/). EMME project region includes Turkey, Georgia, Armenia, Azerbaijan, Syria, Lebanon, Jordan, Iran, Pakistan, and Afghanistan. Both EMME and SHARE projects overlap and Turkey becomes a bridge connecting the two projects. The Middle East region is tectonically and seismically very active part of the Alpine-Himalayan orogenic belt. Many major earthquakes have occurred in this region over the years causing casualties in the millions. The EMME project will use PSHA approach and the existing source models will be revised or modified by the incorporation of newly acquired data. More importantly the most distinguishing aspect of the EMME project from the previous ones will be its dynamic character. This very important characteristic is accomplished by the design of a flexible and scalable database that will permit continuous update, refinement, and analysis. A digital active fault map of the Middle East region is under construction in ArcGIS format. We are developing a database of fault parameters for active faults that are capable of generating earthquakes above a threshold magnitude of Mw≥5.5. Similar to the WGCEP-2007 and UCERF-2 projects, the EMME project database includes information on the geometry and rates of movement of faults in a “Fault Section Database”. The “Fault Section” concept has a physical significance, in that if one or more fault parameters change, a new fault section is defined along a fault zone. So far over 3,000 Fault Sections have been defined and parameterized for the Middle East region. A separate “Paleo-Sites Database” includes information on the timing and amounts of fault displacement for major fault zones. A digital reference library that includes the pdf files of the relevant papers, reports is also being prepared. Another task of the WP-2 of the EMME project is to prepare

  20. Interaction region design for the electron-nucleon collider ENC at FAIR

    SciTech Connect

    Montag, C.; Jankowiak, A.; Lehrach, A.

    2010-05-23

    To facilitate studies of collisions between polarized electron and protons at {radical}s = 14 GeV; constructing an electron-nucleon collider at the FAIR facility has been proposed. This machine would collide the stored 15 GeV polarized proton beam in the HESR with a polarized 3.3 GeV electron beam circulating in an additional storage ring. We describe the interaction region design of this facility, which utilizes the PANDA detector.

  1. Promyelocytic leukemia nuclear bodies associate with transcriptionally active genomic regions

    PubMed Central

    Wang, Jayson; Shiels, Carol; Sasieni, Peter; Wu, Pei Jun; Islam, Suhail A.; Freemont, Paul S.; Sheer, Denise

    2004-01-01

    The promyelocytic leukemia (PML) protein is aggregated into nuclear bodies that are associated with diverse nuclear processes. Here, we report that the distance between a locus and its nearest PML body correlates with the transcriptional activity and gene density around the locus. Genes on the active X chromosome are more significantly associated with PML bodies than their silenced homologues on the inactive X chromosome. We also found that a histone-encoding gene cluster, which is transcribed only in S-phase, is more strongly associated with PML bodies in S-phase than in G0/G1 phase of the cell cycle. However, visualization of specific RNA transcripts for several genes showed that PML bodies were not themselves sites of transcription for these genes. Furthermore, knock-down of PML bodies by RNA interference did not preferentially change the expression of genes closely associated with PML bodies. We propose that PML bodies form in nuclear compartments of high transcriptional activity, but they do not directly regulate transcription of genes in these compartments. PMID:14970191

  2. Muscle activity in the classical singer's shoulder and neck region.

    PubMed

    Pettersen, V; Westgaard, R H

    2002-01-01

    The objective of this study is to characterize the level of use of the trapezius (TR) and the sternocleidomastoideus (STM) muscles by singing students. We further try to lower the activity in both muscles by use of biofeedback (BF) from electromyographic recordings (EMG). We finally examine whether the experiences from the BF session can be transferred into regular singing by maintaining a mental focus on the experiences made in the BF session. Two groups, each consisting of eight conservatory singing students, all in their first or second year of study, volunteered as subjects. Two singing procedures were used, a song and a sustained tone of maximum possible duration. EMG activity was recorded bilaterally from the TR and STM by use of an ambulatory monitoring system. EMG BF appeared to lower muscle activity in the two muscles, thus the experiences made in the BF session could be transferred into regular singing. We conclude that singers, although having an enhanced awareness of posture, still may have overuse of especially the TR muscle, but probably also the STM muscle.

  3. UML activity diagram swimlanes in logic controller design

    NASA Astrophysics Data System (ADS)

    Grobelny, Michał; Grobelna, Iwona

    2015-12-01

    Logic controller behavior can be specified using various techniques, including UML activity diagrams and control Petri nets. Each technique has its advantages and disadvantages. Application of both specification types in one project allows to take benefits from both of them. Additional elements of UML models make it possible to divide a specification into some parts, considered from other point of view (logic controller, user or system). The paper introduces an idea to use UML activity diagrams with swimlanes to increase the understandability of design models.

  4. Regional scale analysis for the design of storage tanks for domestic rainwater harvesting systems.

    PubMed

    Campisano, A; Modica, C

    2012-01-01

    A regional scale analysis for the design of storage tanks for domestic rain water harvesting systems is presented. The analysis is based on the daily water balance simulation of the storage tank by the yield-after-spillage algorithm as tank release rule. Water balances are applied to 17 rainfall gauging stations in Sicily (Italy). Compared with literature existing methods, a novel dimensionless parameter is proposed to better describe the intra-annual character of the rainfall patterns. As a result, easy-to-use regional regressive models to evaluate the water saving performance and the overflow discharges from the tank are provided along with a stepwise procedure for practical application. The regional models demonstrate good fits between model predictions and simulated values of both water savings and overflows from the tank.

  5. Engineering design activities and conceptual change in middle school science

    NASA Astrophysics Data System (ADS)

    Schnittka, Christine G.

    The purpose of this research was to investigate the impact of engineering design classroom activities on conceptual change in science, and on attitudes toward and knowledge about engineering. Students were given a situated learning context and a rationale for learning science in an active, inquiry-based method, and worked in small collaborative groups. One eighth-grade physical science teacher and her students participated in a unit on heat transfer and thermal energy. One class served as the control while two others received variations of an engineering design treatment. Data were gathered from teacher and student entrance and exit interviews, audio recordings of student dialog during group work, video recordings and observations of all classes, pre- and posttests on science content and engineering attitudes, and artifacts and all assignments completed by students. Qualitative and quantitative data were collected concurrently, but analysis took place in two phases. Qualitative data were analyzed in an ongoing manner so that the researcher could explore emerging theories and trends as the study progressed. These results were compared to and combined with the results of the quantitative data analysis. Analysis of the data was carried out in the interpretive framework of analytic induction. Findings indicated that students overwhelmingly possessed alternative conceptions about heat transfer, thermal energy, and engineering prior to the interventions. While all three classes made statistically significant gains in their knowledge about heat and energy, students in the engineering design class with the targeted demonstrations made the most significant gains over the other two other classes. Engineering attitudes changed significantly in the two classes that received the engineering design intervention. Implications from this study can inform teachers' use of engineering design activities in science classrooms. These implications are: (1) Alternative conceptions will

  6. Least cost process design for granular activated carbon adsorbers

    SciTech Connect

    Narbaitz, R.M.; Benedek, A.

    1983-10-01

    Although toxic organics may be removed from industrial effluents by activated carbon adsorbers, the cost of this process is relatively high. Also, adsorber design is complex because of the unsteady-state nature of the process and the numerous operational variables. A package of computer programs has been developed to help to minimise the ultimate cost of 4 types of column configurations. It determines the effect of treatment facility costs of different values for design and operational variables, such as empty bed contact time (EBCT), hydraulic loading, and column configurations. The results of a sample problem indicated that the optimum EBCT for all the column configurations was significantly higher than values typically used by designers.

  7. Spacecraft active thermal control subsystem design and operation considerations

    NASA Technical Reports Server (NTRS)

    Sadunas, J. A.; Lehtinen, A. M.; Nguyen, H. T.; Parish, R.

    1986-01-01

    Future spacecraft missions will be characterized by high electrical power requiring active thermal control subsystems for acquisition, transport, and rejection of waste heat. These systems will be designed to operate with minimum maintenance for up to 10 years, with widely varying externally-imposed environments, as well as the spacecraft waste heat rejection loads. This paper presents the design considerations and idealized performance analysis of a typical thermal control subsystem with emphasis on the temperature control aspects during off-design operation. The selected thermal management subsystem is a cooling loop for a 75-kWe fuel cell subsystem, consisting of a fuel cell heat exchanger, thermal storage, pumps, and radiator. Both pumped-liquid transport and two-phase (liquid/vapor) transport options are presented with examination of similarities and differences of the control requirements for these representative thermal control options.

  8. Design, synthesis and evaluation of antimicrobial activity of N-terminal modified Leucocin A analogues.

    PubMed

    Bodapati, Krishna Chaitanya; Soudy, Rania; Etayash, Hashem; Stiles, Michael; Kaur, Kamaljit

    2013-07-01

    Class IIa bacteriocins are potent antimicrobial peptides produced by lactic acid bacteria to destroy competing microorganisms. The N-terminal domain of these peptides consists of a conserved YGNGV sequence and a disulphide bond. The YGNGV motif is essential for activity, whereas, the two cysteines involved in the disulphide bond can be replaced with hydrophobic residues. The C-terminal region has variable sequences, and folds into a conserved amphipathic α-helical structure. To elucidate the structure-activity relationship in the N-terminal domain of these peptides, three analogues (1-3) of a class IIa bacteriocin, Leucocin A (LeuA), were designed and synthesized by replacing the N-terminal β-sheet residues of the native peptide with shorter β-turn motifs. Such replacement abolished the antibacterial activity in the analogues, however, analogue 1 was able to competitively inhibit the activity of native LeuA. Native LeuA (37-mer) was synthesized using native chemical ligation method in high yield. Solution conformation study using circular dichroism spectroscopy and molecular dynamics simulations suggested that the C-terminal region of analogue 1 adopts helical folding as found in LeuA, while the N-terminal region did not fold into β-sheet conformation. These structure-activity studies highlight the role of proper folding and complete sequence in the activity of class IIa bacteriocins.

  9. HELIOSEISMOLOGY OF PRE-EMERGING ACTIVE REGIONS. I. OVERVIEW, DATA, AND TARGET SELECTION CRITERIA

    SciTech Connect

    Leka, K. D.; Barnes, G.; Birch, A. C.; Dunn, T.; Javornik, B.; Braun, D. C.; Gonzalez-Hernandez, I.

    2013-01-10

    This first paper in a series describes the design of a study testing whether pre-appearance signatures of solar magnetic active regions were detectable using various tools of local helioseismology. The ultimate goal is to understand flux-emergence mechanisms by setting observational constraints on pre-appearance subsurface changes, for comparison with results from simulation efforts. This first paper provides details of the data selection and preparation of the samples, each containing over 100 members, of two populations: regions on the Sun that produced a numbered NOAA active region, and a 'control' sample of areas that did not. The seismology is performed on data from the GONG network; accompanying magnetic data from SOHO/MDI are used for co-temporal analysis of the surface magnetic field. Samples are drawn from 2001-2007, and each target is analyzed for 27.7 hr prior to an objectively determined time of emergence. The results of two analysis approaches are published separately: one based on averages of the seismology- and magnetic-derived signals over the samples, another based on Discriminant Analysis of these signals, for a statistical test of detectable differences between the two populations. We include here descriptions of a new potential-field calculation approach and the algorithm for matching sample distributions over multiple variables. We describe known sources of bias and the approaches used to mitigate them. We also describe unexpected bias sources uncovered during the course of the study and include a discussion of refinements that should be included in future work on this topic.

  10. MAG4 Versus Alternative Techniques for Forecasting Active-Region Flare Productivity

    NASA Technical Reports Server (NTRS)

    Falconer, David A.; Moore, Ronald L.; Barghouty, Abdulnasser F.; Khazanov, Igor

    2014-01-01

    MAG4 is a technique of forecasting an active region's rate of production of major flares in the coming few days from a free-magnetic-energy proxy. We present a statistical method of measuring the difference in performance between MAG4 and comparable alternative techniques that forecast an active region's major-flare productivity from alternative observed aspects of the active region. We demonstrate the method by measuring the difference in performance between the "Present MAG4" technique and each of three alternative techniques, called "McIntosh Active-Region Class," "Total Magnetic Flux," and "Next MAG4." We do this by using (1) the MAG4 database of magnetograms and major-flare histories of sunspot active regions, (2) the NOAA table of the major-flare productivity of each of 60 McIntosh active-region classes of sunspot active regions, and (3) five technique-performance metrics (Heidke Skill Score, True Skill Score, Percent Correct, Probability of Detection, and False Alarm Rate) evaluated from 2000 random two-by-two contingency tables obtained from the databases. We find that (1) Present MAG4 far outperforms both McIntosh Active-Region Class and Total Magnetic Flux, (2) Next MAG4 significantly outperforms Present MAG4, (3) the performance of Next MAG4 is insensitive to the forward and backward temporal windows used, in the range of one to a few days, and (4) forecasting from the free-energy proxy in combination with either any broad category of McIntosh active-region classes or any Mount Wilson active-region class gives no significant performance improvement over forecasting from the free-energy proxy alone (Present MAG4).

  11. Cross-Combined Composite Sampling Designs for Identification of Elevated Regions

    SciTech Connect

    Hathaway, John E.; Walsh, Stephen J.; Sego, Landon H.; Pulsipher, Brent A.

    2013-03-01

    Analyzing soils for contaminants can be costly. Generally, discrete samples are gathered from within a study area, analyzed by a laboratory and the results are used in a site-specific statistical analysis. Because of the heterogeneities that exist in soil samples within study areas, a large amount of variability and skewness may be present in the sample population. This necessitates collecting a large number of samples to obtain reliable inference on the mean contaminant concentration and to understand the spatial patterns for future remediation. Composite or Incremental sampling is a commonly applied method for gathering multiple discrete samples and physically combining them, such that each combination of discrete samples requires a single laboratory analysis, which reduces cost and can improve the estimates of the mean concentration. While incremental sampling can reduce cost and improve mean estimates, current implementations do not readily facilitate the characterization of spatial patterns or the detection of elevated regions within study areas. The methods we present in this work provide efficient estimation and inference for the mean contaminant concentration over the entire spatial area and enable the identification of high contaminant regions within the area of interest. We develop sample design methodologies that explicitly define the characteristics of these designs (such as sample grid layout) and quantify the number of incremental samples that must be obtained under a design criteria to control false positive and false negative (Type I and II) decision errors. We present the sample design theory and specifications as well as results on simulated and real data.

  12. Atmospheric energetics in regions of intense convective activity

    NASA Technical Reports Server (NTRS)

    Fuelberg, H. E.

    1977-01-01

    Synoptic-scale budgets of kinetic and total potential energy are computed using 3- and 6-h data at nine times from NASA's fourth Atmospheric Variability Experiment (AVE IV). Two intense squall lines occurred during the period. Energy budgets for areas that enclose regions of intense convection are shown to have systematic changes that relate to the life cycles of the convection. Some of the synoptic-scale energy processes associated with the convection are found to be larger than those observed in the vicinity of mature cyclones. Volumes enclosing intense convection are found to have large values of cross-contour conversion of potential to kinetic energy and large horizontal export of kinetic energy. Although small net vertical transport of kinetic energy is observed, values at individual layers indicate large upward transport. Transfer of kinetic energy from grid to subgrid scales of motion occurs in the volumes. Latent heat release is large in the middle and upper troposphere and is thought to be the cause of the observed cyclic changes in the budget terms. Total potential energy is found to be imported horizontally in the lower half of the atmosphere, transported aloft, and then exported horizontally. Although local changes of kinetic energy and total potential energy are small, interaction between volumes enclosing convection with surrounding larger volumes is quite large.

  13. Field Trip Guide to Serpentinite, Silica-Carbonate Alteration, and Related Hydrothermal Activity in the Clear Lake Region, California

    SciTech Connect

    Fraser Goff; George Guthrie

    1999-06-01

    This guide is designed to familiarize scientists with the geology, structure, alteration, and fluids typical of California serpentinites for purposes of carbon dioxide sequestration (Lackner et al., 1995). Goff et al. (1997) and Goff and Lackner (1998) describe the geology and geochemistry of some of the serpentinites from this area. Mechanisms of silica-carbonate alteration were outlined by Barnes et al. (1973). Donnelly-Nolan et al. (1993) most recently reviewed relations between regional hydrothermal alteration and Quarternary volcanic activity. Stanley et al. (1998) summarized geophysical characteristics of the region.

  14. FEL Design Studies at LBNL: Activities and Plans

    SciTech Connect

    Corlett, John N.; Fawley, W.; Lidia, S.; Padmore, H.; Penn, G.; Pogorelov, I.; Qiang, J.; Sannibale, F.; Staples, J.; Steier, C.; Venturini, M.; Wan, W.; Wilcox, R.; Zholents, A.

    2007-03-01

    LBNL staff are currently pursuing R&D for future x-ray FELs, and participate in two FEL construction projects. Our strategy is to address the most fundamental challenges, which are the cost-drivers and performance limitations of FEL facilities. An internally funded R&D program is aimed at investigating accelerator physics and technologies in three key areas: (1) Theoretical study, modeling, and experimental development of low emittance, high quantum efficiency cathodes; (2) Design studies of electron beam delivery systems, including emittance manipulations, high-resolution modeling of 6-D phase space, and low-emittance beam transport; and (3) Design studies of optical manipulations of electron beams for seeded and SASE FELs, providing short x-ray pulses of variable duration, synchronous with the seed and pump laser sources, and also long transform-limited pulses with a narrow bandwidth. Design studies of means for production of attosecond x-ray pulses at various wavelengths. We are collaborators in the FERMI{at}Elettra seeded FEL facility under construction at Sincrotrone Trieste, Italy, participating in accelerator design and FEL physics studies, and mechanical and electrical engineering. We are participating in the LCLS project at SLAC, implementing our design of stabilized timing and synchronization systems. Here we outline our long-term objectives, and current activities.

  15. Carnosine: effect on aging-induced increase in brain regional monoamine oxidase-A activity.

    PubMed

    Banerjee, Soumyabrata; Poddar, Mrinal K

    2015-03-01

    Aging is a natural biological process associated with several neurological disorders along with the biochemical changes in brain. Aim of the present investigation is to study the effect of carnosine (0.5-2.5μg/kg/day, i.t. for 21 consecutive days) on aging-induced changes in brain regional (cerebral cortex, hippocampus, hypothalamus and pons-medulla) mitochondrial monoamine oxidase-A (MAO-A) activity with its kinetic parameters. The results of the present study are: (1) The brain regional mitochondrial MAO-A activity and their kinetic parameters (except in Km of pons-medulla) were significantly increased with the increase of age (4-24 months), (2) Aging-induced increase of brain regional MAO-A activity including its Vmax were attenuated with higher dosages of carnosine (1.0-2.5μg/kg/day) and restored toward the activity that observed in young, though its lower dosage (0.5μg/kg/day) were ineffective in these brain regional MAO-A activity, (3) Carnosine at higher dosage in young rats, unlike aged rats significantly inhibited all the brain regional MAO-A activity by reducing their only Vmax excepting cerebral cortex, where Km was also significantly enhanced. These results suggest that carnosine attenuated the aging-induced increase of brain regional MAO-A activity by attenuating its kinetic parameters and restored toward the results of MAO-A activity that observed in corresponding brain regions of young rats.

  16. Framework design for remote sensing monitoring and data service system of regional river basins

    NASA Astrophysics Data System (ADS)

    Fu, Jun'e.; Lu, Jingxuan; Pang, Zhiguo

    2015-08-01

    Regional river basins, transboundary rivers in particular, are shared water resources among multiple users. The tempo-spatial distribution and utilization potentials of water resources in these river basins have a great influence on the economic layout and the social development of all the interested parties in these basins. However, due to the characteristics of cross borders and multi-users in these regions, especially across border regions, basic data is relatively scarce and inconsistent, which bring difficulties in basin water resources management. Facing the basic data requirements in regional river management, the overall technical framework for remote sensing monitoring and data service system in China's regional river basins was designed in the paper, with a remote sensing driven distributed basin hydrologic model developed and integrated within the frame. This prototype system is able to extract most of the model required land surface data by multi-sources and multi-temporal remote sensing images, to run a distributed basin hydrological simulation model, to carry out various scenario analysis, and to provide data services to decision makers.

  17. Image patch analysis of sunspots and active regions. I. Intrinsic dimension and correlation analysis

    NASA Astrophysics Data System (ADS)

    Moon, Kevin R.; Li, Jimmy J.; Delouille, Véronique; De Visscher, Ruben; Watson, Fraser; Hero, Alfred O.

    2016-01-01

    Context. The flare productivity of an active region is observed to be related to its spatial complexity. Mount Wilson or McIntosh sunspot classifications measure such complexity but in a categorical way, and may therefore not use all the information present in the observations. Moreover, such categorical schemes hinder a systematic study of an active region's evolution for example. Aims: We propose fine-scale quantitative descriptors for an active region's complexity and relate them to the Mount Wilson classification. We analyze the local correlation structure within continuum and magnetogram data, as well as the cross-correlation between continuum and magnetogram data. Methods: We compute the intrinsic dimension, partial correlation, and canonical correlation analysis (CCA) of image patches of continuum and magnetogram active region images taken from the SOHO-MDI instrument. We use masks of sunspots derived from continuum as well as larger masks of magnetic active regions derived from magnetogram to analyze separately the core part of an active region from its surrounding part. Results: We find relationships between the complexity of an active region as measured by its Mount Wilson classification and the intrinsic dimension of its image patches. Partial correlation patterns exhibit approximately a third-order Markov structure. CCA reveals different patterns of correlation between continuum and magnetogram within the sunspots and in the region surrounding the sunspots. Conclusions: Intrinsic dimension has the potential to distinguish simple from complex active regions. These results also pave the way for patch-based dictionary learning with a view toward automatic clustering of active regions.

  18. Colors of active regions on comet 67P

    NASA Astrophysics Data System (ADS)

    Oklay, N.; Vincent, J.-B.; Sierks, H.; Besse, S.; Fornasier, S.; Barucci, M. A.; Lara, L.; Scholten, F.; Preusker, F.; Lazzarin, M.; Pajola, M.; La Forgia, F.

    2015-10-01

    The OSIRIS (Optical, Spectroscopic, and Infrared Remote Imaging System) scientific imager (Keller et al. 2007) is successfully delivering images of comet 67P/Churyumov-Gerasimenko from its both wide angle camera (WAC) and narrow angle camera (NAC) since ESA's spacecraft Rosetta's arrival to the comet. Both cameras are equipped with filters covering the wavelength range of about 200 nm to 1000 nm. The comet nucleus is mapped with different combination of the filters in resolutions up to 15 cm/px. Besides the determination of the surface morphology in great details (Thomas et al. 2015), such high resolution images provided us a mean to unambiguously link some activity in the coma to a series of pits on the nucleus surface (Vincent et al. 2015).

  19. Active Learning by Design: An Undergraduate Introductory Public Health Course

    PubMed Central

    Yeatts, Karin B.

    2014-01-01

    Principles of active learning were used to design and implement an introductory public health course. Students were introduced to the breadth and practice of public health through team and individual-based activities. Team assignments covered topics in epidemiology, biostatistics, health behavior, nutrition, maternal and child health, environment, and health policy. Students developed an appreciation of the population perspective through an “experience” trip and related intervention project in a public health area of their choice. Students experienced several key critical component elements of a public health undergraduate major; they explored key public health domains, experience public health practice, and integrated concepts with their assignments. In this paper, course assignments, lessons learned, and student successes are described. Given the increased growth in the undergraduate public health major, these active learning assignments may be of interest to undergraduate public health programs at both liberal arts colleges and research universities. PMID:25566526

  20. Activation product safety in the ARIES-I reactor design

    SciTech Connect

    Herring, J.S. ); Sze, D.K. ); Wong, C.; Cheng, E.T. ); Grotz, S.P. )

    1990-01-01

    The ARIES design effort has sought to maximize the environmental and safety advantages of fusion through careful selection of materials and careful design. Three goals are that the reactor achieve inherent or passive safety, that no public evacuation plan be necessary and that the waste be disposable as 10CFR61 Class C waste. The ARIES-I reactor consists of a SiC composite structure for the first wall and blanket, cooled by 10 MPa He. The breeder is Li{sub 2}ZrO{sub 3}, although Li{sub 2}O and Li{sub 4}SiO{sub 4} were also considered. The divertor consists of SiC composite tubes coated with 2 mm of tungsten. Due to the minimal afterheat of this blanket design, LOCA calculations indicate maximum temperatures will not cause damage if the plasma is promptly extinguished. Two primary safety issues are the zirconium in the breeder and tungsten on the divertor. Li{sub 2}ZrO{sub 3} was chosen because of its demonstrated high-temperature stability. The other breeders have lower afterheat and activation. Use of zirconium in the breeder will necessitate isotopic tailoring to remove {sup 90}Zr and {sup 94}Zr. The 5.8 tonnes of W on the divertor would also have to be tailored to remove {sup 186}W and/or to concentrate {sup 183}W. Thus the ARIES-I design achieves the passive safety and low-level waste disposal criteria with respect to activation products. Development of low activation materials to replace zirconium and tungsten is needed to avoid requiring an evacuation plan.

  1. An active region model for capturing fractal flow patterns in unsaturated soils: model development.

    PubMed

    Liu, H H; Zhang, R; Bodvarsson, G S

    2005-11-01

    Preferential flow commonly observed in unsaturated soils allows rapid movement of solute from the soil surface or vadose zone to the groundwater, bypassing a significant volume of unsaturated soil and increasing the risk of groundwater contamination. A variety of evidence indicates that complex preferential patterns observed from fields are fractals. In this study, we developed a relatively simple active region model to incorporate the fractal flow pattern into the continuum approach. In the model, the flow domain is divided into active and inactive regions. Flow occurs preferentially in the active region (characterized by fractals), and inactive region is simply bypassed. A new constitutive relationship (the portion of the active region as a function of saturation) was derived. The validity of the proposed model is demonstrated by the consistency between field observations and the new constitutive relationship.

  2. An Active Region Model for Capturing Fractal Flow Patterns inUnsaturated Soils: Model Development

    SciTech Connect

    Liu, Hui-Hai; Zhang, R.; Bodvarsson, Gudmundur S.

    2005-06-11

    Preferential flow commonly observed in unsaturated soils allows rapid movement of solute from the soil surface or vadose zone to the groundwater, bypassing a significant volume of unsaturated soil and increasing the risk of groundwater contamination. A variety of evidence indicates that complex preferential patterns observed from fields are fractals. In this study, we developed a relatively simple active region model to incorporate the fractal flow pattern into the continuum approach. In the model, the flow domain is divided into active and inactive regions. Flow occurs preferentially in the active region (characterized by fractals), and inactive region is simply bypassed. A new constitutive relationship (the portion of the active region as a function of saturation) was derived. The validity of the proposed model is demonstrated by the consistency between field observations and the new constitutive relationship.

  3. A SYSTEMATIC SURVEY OF HIGH-TEMPERATURE EMISSION IN SOLAR ACTIVE REGIONS

    SciTech Connect

    Warren, Harry P.; Winebarger, Amy R.; Brooks, David H.

    2012-11-10

    The recent analysis of observations taken with the EUV Imaging Spectrometer and X-Ray Telescope instruments on Hinode suggests that well-constrained measurements of the temperature distribution in solar active regions can finally be made. Such measurements are critical for constraining theories of coronal heating. Past analysis, however, has suffered from limited sample sizes and large uncertainties at temperatures between 5 and 10 MK. Here we present a systematic study of the differential emission measure distribution in 15 active region cores. We focus on measurements in the 'inter-moss' region, that is, the region between the loop footpoints, where the observations are easier to interpret. To reduce the uncertainties at the highest temperatures we present a new method for isolating the Fe XVIII emission in the AIA/SDO 94 A channel. The resulting differential emission measure distributions confirm our previous analysis showing that the temperature distribution in an active region core is often strongly peaked near 4 MK. We characterize the properties of the emission distribution as a function of the total unsigned magnetic flux. We find that the amount of high-temperature emission in the active region core is correlated with the total unsigned magnetic flux, while the emission at lower temperatures, in contrast, is inversely related. These results provide compelling evidence that high-temperature active region emission is often close to equilibrium, although weaker active regions may be dominated by evolving million degree loops in the core.

  4. Regional vulnerability of the hippocampus to repeated motor activity deprivation.

    PubMed

    Faraji, Jamshid; Soltanpour, Nabiollah; Moeeini, Reza; Hosseini, Seyed Abedin; Pakdel, Shiva; Moharrerie, Alireza; Arjang, Kaveh; Soltanpour, Nasrin; Metz, Gerlinde A S

    2016-03-15

    Spontaneous vertical and horizontal exploratory movements are integral components of rodent behavior. Little is known, however, about the structural and functional consequences of restricted spontaneous exploration. Here, we report two experiments to probe whether restriction in vertical activity (rearing) in rats could induce neuro-hormonal and behavioral disturbances. Rearing movements in rats were deprived for 3h/day for 30 consecutive days by placing the animal into a circular tunnel task. Rats temporarily deprived of rearing behavior showed elevated plasma corticosterone levels but no detectable psychological distress and/or anxiety-related behavior within an elevated plus maze. However, rats emitted a greater number of 22-kHz ultrasonic vocalizations and spent significantly more time vocalizing than controls when deprived of their rearing behavior. Despite intact spatial performance within wet- and dry-land spatial tasks, rearing-deprived rats also exhibited a significant alteration in search strategies within both spatial tasks along with reduced volume and neuron number in the hippocampal subregion CA2. These data suggest a new approach to test the importance of free exploratory behavior in endocrine and structural manifestations. The results support a central role of the CA2 in spontaneous exploratory behavior and vulnerability to psychological stress. PMID:26723539

  5. Regional vulnerability of the hippocampus to repeated motor activity deprivation.

    PubMed

    Faraji, Jamshid; Soltanpour, Nabiollah; Moeeini, Reza; Hosseini, Seyed Abedin; Pakdel, Shiva; Moharrerie, Alireza; Arjang, Kaveh; Soltanpour, Nasrin; Metz, Gerlinde A S

    2016-03-15

    Spontaneous vertical and horizontal exploratory movements are integral components of rodent behavior. Little is known, however, about the structural and functional consequences of restricted spontaneous exploration. Here, we report two experiments to probe whether restriction in vertical activity (rearing) in rats could induce neuro-hormonal and behavioral disturbances. Rearing movements in rats were deprived for 3h/day for 30 consecutive days by placing the animal into a circular tunnel task. Rats temporarily deprived of rearing behavior showed elevated plasma corticosterone levels but no detectable psychological distress and/or anxiety-related behavior within an elevated plus maze. However, rats emitted a greater number of 22-kHz ultrasonic vocalizations and spent significantly more time vocalizing than controls when deprived of their rearing behavior. Despite intact spatial performance within wet- and dry-land spatial tasks, rearing-deprived rats also exhibited a significant alteration in search strategies within both spatial tasks along with reduced volume and neuron number in the hippocampal subregion CA2. These data suggest a new approach to test the importance of free exploratory behavior in endocrine and structural manifestations. The results support a central role of the CA2 in spontaneous exploratory behavior and vulnerability to psychological stress.

  6. Biological activities of the homologous loop regions in the laminin α chain LG modules.

    PubMed

    Katagiri, Fumihiko; Hara, Toshihiro; Yamada, Yuji; Urushibata, Shunsuke; Hozumi, Kentaro; Kikkawa, Yamato; Nomizu, Motoyoshi

    2014-06-10

    Each laminin α chain (α1-α5 chains) has chain-specific diverse biological functions. The C-terminal globular domain of the α chain consists of five laminin-like globular (LG1-5) modules and plays a critical role in biological activities. The LG modules consist of a 14-stranded β-sheet (A-N) sandwich structure. Previously, we described the chain-specific biological activities of the loop regions between the E and F strands in the LG4 modules using five homologous peptides (G4EF1-G4EF5). Here, we further analyze the biological activities of the E-F strands loop regions in the rest of LG modules. We designed 20 homologous peptides (approximately 20 amino acid length), and 17 soluble peptides were used for the cell attachment assay. Thirteen peptides promoted cell attachment activity with different cell morphologies. Cell attachment to peptides G1EF1, G1EF2, G2EF1, G3EF4, and G5EF4 was inhibited by heparin, and peptides G1EF1, G1EF2, and G2EF1 specifically bound to syndecan-overexpressing cells. Cell attachment to peptides G2EF3, G3EF1, G3EF3, G5EF1, G5EF3, and G5EF5 was inhibited EDTA. Further, cell attachment to peptides G3EF3, G5EF1, and G5EF5 was inhibited by both anti-integrin α2 and β1 antibodies, whereas cell attachment to peptide G5EF3 was inhibited by only anti-integrin β1 antibody. Cell attachment to peptides G1EF4, G3EF4, and G5EF4 was inhibited by both heparin and EDTA and was not inhibited by anti-integrin antibodies. The active peptide sequence alignments suggest that the syndecan-binding peptides contain a "basic amino acid (BAA)-Gly-BAA" motif in the middle of the molecule and that the integrin-binding peptides contain an "acidic amino acid (AAA)"-Gly-BAA motif. Core-switched peptide analyses suggested that the "BAA-Gly-BAA" motif is critical for binding to syndecans and that the "AAA-Gly-BAA" motif has potential to recognize integrins. These findings are useful for understanding chain-specific biological activities of laminins and to evaluate

  7. Triggering an Eruptive Flare by Emerging Flux in a Solar Active-Region Complex

    NASA Astrophysics Data System (ADS)

    Louis, Rohan E.; Kliem, Bernhard; Ravindra, B.; Chintzoglou, Georgios

    2015-12-01

    A flare and fast coronal mass ejection originated between solar active regions NOAA 11514 and 11515 on 2012 July 1 (SOL2012-07-01) in response to flux emergence in front of the leading sunspot of the trailing region 11515. Analyzing the evolution of the photospheric magnetic flux and the coronal structure, we find that the flux emergence triggered the eruption by interaction with overlying flux in a non-standard way. The new flux neither had the opposite orientation nor a location near the polarity inversion line, which are favorable for strong reconnection with the arcade flux under which it emerged. Moreover, its flux content remained significantly smaller than that of the arcade ({≈} 40 %). However, a loop system rooted in the trailing active region ran in part under the arcade between the active regions, passing over the site of flux emergence. The reconnection with the emerging flux, leading to a series of jet emissions into the loop system, caused a strong but confined rise of the loop system. This lifted the arcade between the two active regions, weakening its downward tension force and thus destabilizing the considerably sheared flux under the arcade. The complex event was also associated with supporting precursor activity in an enhanced network near the active regions, acting on the large-scale overlying flux, and with two simultaneous confined flares within the active regions.

  8. THE FORMATION AND MAGNETIC STRUCTURES OF ACTIVE-REGION FILAMENTS OBSERVED BY NVST, SDO, AND HINODE

    SciTech Connect

    Yan, X. L.; Xue, Z. K.; Wang, J. C.; Xiang, Y. Y.; Kong, D. F.; Yang, L. H.; Pan, G. M.

    2015-08-15

    To better understand the properties of solar active-region filaments, we present a detailed study on the formation and magnetic structures of two active-region filaments in active region NOAA 11884 during a period of four days. It is found that the shearing motion of the opposite magnetic polarities and the rotation of the small sunspots with negative polarity play an important role in the formation of two active-region filaments. During the formation of these two active-region filaments, one foot of the filaments was rooted in a small sunspot with negative polarity. The small sunspot rotated not only around another small sunspot with negative polarity, but also around the center of its umbra. By analyzing the nonlinear force-free field extrapolation using the vector magnetic fields in the photosphere, twisted structures were found in the two active-region filaments prior to their eruptions. These results imply that the magnetic fields were dragged by the shearing motion between opposite magnetic polarities and became more horizontal. The sunspot rotation twisted the horizontal magnetic fields and finally formed the twisted active-region filaments.

  9. A note on chromospheric fine structure at active region polarity boundaries.

    NASA Technical Reports Server (NTRS)

    Prata, S. W.

    1971-01-01

    High resolution H-alpha filtergrams from Big Bear Solar Observatory reveal that some filamentary features in active regions have fine structure and hence magnetic field transverse to the gross structure and the zero longitudinal field line. These features are distinct from the usual active region filament, in which fine structure, magnetic field, and filament are all parallel to the zero longitudinal field line. The latter occur on boundaries between regions of weaker fields, while the former occur at boundaries between regions of stronger field.

  10. Active region upflow plasma: its relation to small activity and the solar wind

    NASA Astrophysics Data System (ADS)

    Mandrini, Cristina H.; Culhane, J. Leonard; Cristiani, Germán; Vásquez, Alberto; Van Driel-Gesztelyi, Lidia; Baker, Deborah; Pick, Monique; Demoulin, Pascal; Nuevo, Federico

    Recent studies show that active region (AR) upflowing plasma, observed by the Hinode EUV Imaging Spectrometer (EIS), can gain access to open field lines and be released into the solar wind via magnetic interchange reconnection occurring below the source surface at magnetic null-points in pseudo-streamer configurations. When only one simple bipolar AR is present on the Sun and it is fully covered by the separatrix of a streamer, like AR 10978 on December 2007, it seems unlikely that the upflowing AR plasma could find its way into the slow solar wind. However, signatures of plasma with AR composition at 1 AU that appears to originate from the West of AR 10978 were recently found by Culhane and coworkers. We present a detailed topology analysis of AR 10978 based on a linear force-free magnetic field model at the AR scale, combined with a global PFSS model. This allows us, on one hand, to explain the variations observed in the upflows to the West of the AR as the result of magnetic reconnection at quasi-separatrix layers (QSLs). While at a global scale, we show that reconnection, occurring in at least two main steps, first at QSLs and later at a high-altitude coronal null-point, allows the AR plasma to get around the topological obstacle of the streamer separatrix and be released into the solar wind.

  11. RF cavity design exploiting a new derivative-free trust region optimization approach.

    PubMed

    Hassan, Abdel-Karim S O; Abdel-Malek, Hany L; Mohamed, Ahmed S A; Abuelfadl, Tamer M; Elqenawy, Ahmed E

    2015-11-01

    In this article, a novel derivative-free (DF) surrogate-based trust region optimization approach is proposed. In the proposed approach, quadratic surrogate models are constructed and successively updated. The generated surrogate model is then optimized instead of the underlined objective function over trust regions. Truncated conjugate gradients are employed to find the optimal point within each trust region. The approach constructs the initial quadratic surrogate model using few data points of order O(n), where n is the number of design variables. The proposed approach adopts weighted least squares fitting for updating the surrogate model instead of interpolation which is commonly used in DF optimization. This makes the approach more suitable for stochastic optimization and for functions subject to numerical error. The weights are assigned to give more emphasis to points close to the current center point. The accuracy and efficiency of the proposed approach are demonstrated by applying it to a set of classical bench-mark test problems. It is also employed to find the optimal design of RF cavity linear accelerator with a comparison analysis with a recent optimization technique. PMID:26644929

  12. The effects of activation procedures on regional cerebral blood flow in humans

    SciTech Connect

    Rozenfeld, D.; Wolfson, L.I.

    1981-07-01

    Regional cerebral blood flow (r-CBF) can be measured using 133XE and collimated detectors. The radionuclide can be administered either by inhalation or intracarotid injection. Comparison of blood flow determinations at rest and during performance of an activity identifies those brain regions that become active during the performance of the activity. Relatively specific patterns of r-CBF are observed during hand movements, sensory stimulation, eye movements, speech, listening, and reading. Regional CBF changes during reasoning and memorization are less specific and less well characterized. It is clear that brain lesions affect r-CBF responses to various activities, but this effect has not been well correlated with functional deficits or recovery of function. Regional CBF measurement gives information about brain activity and the functional response to experimental manipulation. This approach may well add to our understanding of normal, as well as pathologic, brain functioning.

  13. Crossing Active Faults on the Sakhalin II Onshore Pipeline Route: Pipeline Design and Risk Analysis

    SciTech Connect

    Mattiozzi, Pierpaolo; Strom, Alexander

    2008-07-08

    Twin oil (20 and 24 inch) and gas (20 and 48 inch) pipeline systems stretching 800 km are being constructed to connect offshore hydrocarbon deposits from the Sakhalin II concession in the North to an LNG plant and oil export terminal in the South of Sakhalin island. The onshore pipeline route follows a regional fault zone and crosses individual active faults at 19 locations. Sakhalin Energy, Design and Construction companies took significant care to ensure the integrity of the pipelines, should large seismic induced ground movements occur during the Operational life of the facilities. Complex investigations including the identification of the active faults, their precise location, their particular displacement values and assessment of the fault kinematics were carried out to provide input data for unique design solutions. Lateral and reverse offset displacements of 5.5 and 4.5 m respectively were determined as the single-event values for the design level earthquake (DLE) - the 1000-year return period event. Within the constraints of a pipeline route largely fixed, the underground pipeline fault crossing design was developed to define the optimum routing which would minimize stresses and strain using linepipe materials which had been ordered prior to the completion of detailed design, and to specify requirements for pipe trenching shape, materials, drainage system, etc. Detailed Design was performed with due regard to actual topography and to avoid the possibility of the trenches freezing in winter, the implementation of specific drainage solutions and thermal protection measures.

  14. Crossing Active Faults on the Sakhalin II Onshore Pipeline Route: Pipeline Design and Risk Analysis

    NASA Astrophysics Data System (ADS)

    Mattiozzi, Pierpaolo; Strom, Alexander

    2008-07-01

    Twin oil (20 & 24 inch) and gas (20 & 48 inch) pipeline systems stretching 800 km are being constructed to connect offshore hydrocarbon deposits from the Sakhalin II concession in the North to an LNG plant and oil export terminal in the South of Sakhalin island. The onshore pipeline route follows a regional fault zone and crosses individual active faults at 19 locations. Sakhalin Energy, Design and Construction companies took significant care to ensure the integrity of the pipelines, should large seismic induced ground movements occur during the Operational life of the facilities. Complex investigations including the identification of the active faults, their precise location, their particular displacement values and assessment of the fault kinematics were carried out to provide input data for unique design solutions. Lateral and reverse offset displacements of 5.5 and 4.5 m respectively were determined as the single-event values for the design level earthquake (DLE)—the 1000-year return period event. Within the constraints of a pipeline route largely fixed, the underground pipeline fault crossing design was developed to define the optimum routing which would minimize stresses and strain using linepipe materials which had been ordered prior to the completion of detailed design, and to specify requirements for pipe trenching shape, materials, drainage system, etc. Detailed Design was performed with due regard to actual topography and to avoid the possibility of the trenches freezing in winter, the implementation of specific drainage solutions and thermal protection measures.

  15. Further Progress on a Design for a Super-B Interaction Region

    SciTech Connect

    Sullivan, M; Bertsche, K.; Seeman, J.; Wienands, U.; Biagini, M.E.; Raimondi, P.; Paoloni, E.; Bettoni, S.; /CERN

    2009-05-20

    We present an improved design for a SuperB interaction region. The new design minimizes local bending of the two colliding beams by separating all beam magnetic elements near the Interaction Point (IP). The total crossing angle at the IP is increased from 48 mrad to 60 mrad. The first magnetic element is a six slice Permanent Magnet (PM) quadrupole with an elliptical aperture allowing us to increase the vertical space for the beam. This magnet starts 36 cm from the Interaction Point (IP). This magnet is only seen by the Low-Energy Beam (LEB), the High-Energy Beam (HEB) has a drift space at this location. This allows the preliminary focusing of the LEB which has a smaller beta y* at the IP than the HEB. The rest of the final focusing for both beams is achieved by two super-conducting side-by-side quadrupoles (QD0 and QF1). These sets of magnets are enclosed in a warm bore cryostat located behind the PM quadrupole for the LEB. We describe this design for the interaction region.

  16. Design, test, and evaluation of three active flutter suppression controllers

    NASA Technical Reports Server (NTRS)

    Adams, William M., Jr.; Christhilf, David M.; Waszak, Martin R.; Mukhopadhyay, Vivek; Srinathkumar, S.

    1992-01-01

    Three control law design techniques for flutter suppression are presented. Each technique uses multiple control surfaces and/or sensors. The first method uses traditional tools (such as pole/zero loci and Nyquist diagrams) for producing a controller that has minimal complexity and which is sufficiently robust to handle plant uncertainty. The second procedure uses linear combinations of several accelerometer signals and dynamic compensation to synthesize the model rate of the critical mode for feedback to the distributed control surfaces. The third technique starts with a minimum-energy linear quadratic Gaussian controller, iteratively modifies intensity matrices corresponding to input and output noise, and applies controller order reduction to achieve a low-order, robust controller. The resulting designs were implemented digitally and tested subsonically on the active flexible wing wind-tunnel model in the Langley Transonic Dynamics Tunnel. Only the traditional pole/zero loci design was sufficiently robust to errors in the nominal plant to successfully suppress flutter during the test. The traditional pole/zero loci design provided simultaneous suppression of symmetric and antisymmetric flutter with a 24-percent increase in attainable dynamic pressure. Posttest analyses are shown which illustrate the problems encountered with the other laws.

  17. Development of a code for wall contour design in the transonic region of axisymmetric and square nozzles

    NASA Technical Reports Server (NTRS)

    Alcenius, Timothy; Schneider, Steven P.

    1994-01-01

    Nozzle design codes developed earlier under NAG1-1133 were modified and used in order to design a supersonic wind tunnel nozzle with square cross sections. As part of the design process, a computer code was written to implement the Hopkins and Hill perturbation solution for the flow in the transonic region of axisymmetric nozzles. This technique is used to design the bleed slot of quiet-flow nozzles. This new design code is documented in this report.

  18. Design, Synthesis, and Antifungal Activity of New α-Aminophosphonates

    PubMed Central

    Rezaei, Zahra; Khabnadideh, Soghra; Zomorodian, Kamiar; Pakshir, Keyvan; Nadali, Setareh; Mohtashami, Nadia; Faghih Mirzaei, Ehsan

    2011-01-01

    α-Aminophosphonates are bioisosteres of amino acids and have several pharmacological activities. These compounds have been synthesized by various routes from reaction between amine, aldehyde, and phosphite compounds. In order to synthesize α-aminophosphonates, catalytic effect of CuCl2 was compared with FeCl3. Also all designed structures as well as griseofulvin were docked into the active site of microtubule (1JFF), using Autodock program. The results showed that the reactions were carried out in the presence of CuCl2 in lower yields, and also the time of reaction was longer in comparison with FeCl3. The chemical structures of the new compounds were confirmed by spectral analyses. The compounds were investigated for antifungal activity against several fungi in comparison with griseofulvin. An indole-derived bis(α-aminophosphonates) with the best negative ΔG in docking study showed maximum antifungal activity against Microsporum canis, and other investigated compounds did not have a good antifungal activity. PMID:25954522

  19. Design of active orthoses for a robotic gait rehabilitation system

    NASA Astrophysics Data System (ADS)

    Villa-Parra, A. C.; Broche, L.; Delisle-Rodríguez, D.; Sagaró, R.; Bastos, T.; Frizera-Neto, A.

    2015-09-01

    An active orthosis (AO) is a robotic device that assists both human gait and rehabilitation therapy. This work proposes portable AOs, one for the knee joint and another for the ankle joint. Both AOs will be used to complete a robotic system that improves gait rehabilitation. The requirements for actuator selection, the biomechanical considerations during the AO design, the finite element method, and a control approach based on electroencephalographic and surface electromyographic signals are reviewed. This work contributes to the design of AOs for users with foot drop and knee flexion impairment. However, the potential of the proposed AOs to be part of a robotic gait rehabilitation system that improves the quality of life of stroke survivors requires further investigation.

  20. System design for active vibration control of aerospace structures

    NASA Astrophysics Data System (ADS)

    Shankar, V.; Nagaraja, B. V.; Balasubramaniam, R.; Shree S, Amrutha; Muthaiah, Skanda N.

    2003-10-01

    Instrumentation, electronics, digital signal processing and related software form the basic building blocks of a system for implementation of Active Vibration Control (AVC) for smart aerospace structures. This paper essentially deals with the design, development and implementation of a 4 channel analog input sub-system essentially consisting of charge amplifiers, filters, gain amplifiers & Analog to Digital Converters (ADC), the subsequent Digital Signal Processor (DSP) hardware for implementation of the controller and finally a 4 Channel analog output subsystem consisting of Digital to Analog Converters (DAC), reconstruction filters & high voltage amplifiers. This system essentially interfaces to a structure with piezo-ceramic sensors and actuators for implementation of real time AVC on a smart beam. The paper also highlights some of the new ideas that have been incorporated into the system design.

  1. Incorporating 3D-printing technology in the design of head-caps and electrode drives for recording neurons in multiple brain regions

    PubMed Central

    DeLucca, Michael V.; Haufler, Darrell; Paré, Denis

    2015-01-01

    Recent advances in recording and computing hardware have enabled laboratories to record the electrical activity of multiple brain regions simultaneously. Lagging behind these technical advances, however, are the methods needed to rapidly produce microdrives and head-caps that can flexibly accommodate different recording configurations. Indeed, most available designs target single or adjacent brain regions, and, if multiple sites are targeted, specially constructed head-caps are used. Here, we present a novel design style, for both microdrives and head-caps, which takes advantage of three-dimensional printing technology. This design facilitates targeting of multiple brain regions in various configurations. Moreover, the parts are easily fabricated in large quantities, with only minor hand-tooling and finishing required. PMID:25652930

  2. Incorporating 3D-printing technology in the design of head-caps and electrode drives for recording neurons in multiple brain regions.

    PubMed

    Headley, Drew B; DeLucca, Michael V; Haufler, Darrell; Paré, Denis

    2015-04-01

    Recent advances in recording and computing hardware have enabled laboratories to record the electrical activity of multiple brain regions simultaneously. Lagging behind these technical advances, however, are the methods needed to rapidly produce microdrives and head-caps that can flexibly accommodate different recording configurations. Indeed, most available designs target single or adjacent brain regions, and, if multiple sites are targeted, specially constructed head-caps are used. Here, we present a novel design style, for both microdrives and head-caps, which takes advantage of three-dimensional printing technology. This design facilitates targeting of multiple brain regions in various configurations. Moreover, the parts are easily fabricated in large quantities, with only minor hand-tooling and finishing required.

  3. Incorporating 3D-printing technology in the design of head-caps and electrode drives for recording neurons in multiple brain regions.

    PubMed

    Headley, Drew B; DeLucca, Michael V; Haufler, Darrell; Paré, Denis

    2015-04-01

    Recent advances in recording and computing hardware have enabled laboratories to record the electrical activity of multiple brain regions simultaneously. Lagging behind these technical advances, however, are the methods needed to rapidly produce microdrives and head-caps that can flexibly accommodate different recording configurations. Indeed, most available designs target single or adjacent brain regions, and, if multiple sites are targeted, specially constructed head-caps are used. Here, we present a novel design style, for both microdrives and head-caps, which takes advantage of three-dimensional printing technology. This design facilitates targeting of multiple brain regions in various configurations. Moreover, the parts are easily fabricated in large quantities, with only minor hand-tooling and finishing required. PMID:25652930

  4. Design and validation of the Regional Anaesthesia Procedural Skills Assessment Tool.

    PubMed

    Chuan, A; Graham, P L; Wong, D M; Barrington, M J; Auyong, D B; Cameron, A J D; Lim, Y C; Pope, L; Germanoska, B; Forrest, K; Royse, C F

    2015-12-01

    The aim of this study was to create and evaluate the validity, reliability and feasibility of the Regional Anaesthesia Procedural Skills tool, designed for the assessment of all peripheral and neuraxial blocks using all nerve localisation techniques. The first phase was construction of a 25-item checklist by five regional anaesthesia experts using a Delphi process. This checklist was combined with a global rating scale to create the tool. In the second phase, initial validation by 10 independent anaesthetists using a test-retest methodology was successful (Cohen kappa ≥ 0.70 for inter-rater agreement, scores between test to retest, paired t-test, p > 0.12). In the third phase, 70 clinical videos of trainees were scored by three blinded international assessors. The RAPS tool exhibited face validity (p < 0.026), construct validity (p < 0.001), feasibility (mean time to score < 3.9 min), and overall reliability (intraclass correlation coefficient 0.80 (95% CI 0.67-0.88)). The Regional Anaesthesia Procedural Skills tool used in this study is a valid and reliable assessment tool to score the performance of trainees for regional anaesthesia.

  5. Evolution of Magnetic Field Twist and Tilt in Active Region NOAA 10930

    NASA Astrophysics Data System (ADS)

    Ravindra, B.; Venkatakrishnan, P.; Tiwari, Sanjiv Kumar

    2011-07-01

    Magnetic twist of the active region has been measured over a decade using photospheric vector field data, chromospheric H_alpha data, and coronal loop data. The twist and tilt of the active regions have been measured at the photospheric level with the vector magnetic field measurements. The active region NOAA 10930 is a highly twisted emerging region. The same active region produced several flares and has been extensively observed by Hinode. In this paper, we will show the evolution of twist and tilt in this active region leading up to the two X-class flares. We find that the twist initially increases with time for a few days with a simultaneous decrease in the tilt until before the X3.4 class flare on December 13, 2006. The total twist acquired by the active region is larger than one complete winding before the X3.4 class flare and it decreases in later part of observations. The injected helicity into the corona is negative and it is in excess of 10^43 Mx^2 before the flares.

  6. Design of an active magnetic regenerator test apparatus

    NASA Astrophysics Data System (ADS)

    Rowe, A. M.; Barclay, J. A.

    2002-05-01

    The Active Magnetic Regenerator (AMR) has been shown to be a refrigeration technology with high efficiencies. Complex thermodynamic interactions in the regenerator, a shortage of suitable magnetic refrigerants, and difficulty in acquiring accurate experimental data have combined to hamper the development of AMR refrigerators. An apparatus to dynamically characterize the behavior of AMR beds is a valuable tool in furthering the development of the technology. This paper describes the design and construction of an AMR test apparatus. For initial tests, the apparatus has been used to examine the performance of Gd AMR beds operating in 2 T fields.

  7. Shuttle Orbiter Active Thermal Control Subsystem design and flight experience

    NASA Technical Reports Server (NTRS)

    Bond, Timothy A.; Metcalf, Jordan L.; Asuncion, Carmelo

    1991-01-01

    The paper examines the design of the Space Shuttle Orbiter Active Thermal Control Subsystem (ATCS) constructed for providing the vehicle and payload cooling during all phases of a mission and during ground turnaround operations. The operation of the Shuttle ATCS and some of the problems encountered during the first 39 flights of the Shuttle program are described, with special attention given to the major problems encountered with the degradation of the Freon flow rate on the Orbiter Columbia, the Flash Evaporator Subsystem mission anomalies which occurred on STS-26 and STS-34, and problems encountered with the Ammonia Boiler Subsystem. The causes and the resolutions of these problems are discussed.

  8. Design and activity of a cyclic mini-β-defensin analog: a novel antimicrobial tool.

    PubMed

    Scudiero, Olga; Nigro, Ersilia; Cantisani, Marco; Colavita, Irene; Leone, Marilisa; Mercurio, Flavia Anna; Galdiero, Massimiliano; Pessi, Antonello; Daniele, Aurora; Salvatore, Francesco; Galdiero, Stefania

    2015-01-01

    We have designed a cyclic 17-amino acid β-defensin analog featuring a single disulfide bond. This analog, designated "AMC" (ie, antimicrobial cyclic peptide), combines the internal hydrophobic domain of hBD1 and the C-terminal charged region of hBD3. The novel peptide was synthesized and characterized by nuclear magnetic resonance spectroscopy. The antimicrobial activities against gram-positive and gram-negative bacteria as well as against herpes simplex virus type 1 were analyzed. The cytotoxicity and serum stability were assessed. Nuclear magnetic resonance of AMC in aqueous solution suggests that the structure of the hBD1 region, although not identical, is preserved. Like the parent defensins, AMC is not cytotoxic for CaCo-2 cells. Interestingly, AMC retains the antibacterial activity of the parent hBD1 and hBD3 against Pseudomonas aeruginosa, Enterococcus faecalis, and Escherichia coli, and exerts dose-dependent activity against herpes simplex virus type 1. Moreover, while the antibacterial and antiviral activities of the oxidized and reduced forms of the parent defensins are similar, those of AMC are significantly different, and oxidized AMC is also considerably more stable in human serum. Taken together, our data also suggest that this novel peptide may be added to the arsenal of tools available to combat antibiotic-resistant infectious diseases, particularly because of its potential for encapsulation in a nanomedicine vector.

  9. Mapping brain region activity during chewing: a functional magnetic resonance imaging study.

    PubMed

    Onozuka, M; Fujita, M; Watanabe, K; Hirano, Y; Niwa, M; Nishiyama, K; Saito, S

    2002-11-01

    Mastication has been suggested to increase neuronal activities in various regions of the human brain. However, because of technical difficulties, the fine anatomical and physiological regions linked to mastication have not been fully elucidated. Using functional magnetic resonance imaging during cycles of rhythmic gum-chewing and no chewing, we therefore examined the interaction between chewing and brain regional activity in 17 subjects (aged 20-31 years). In all subjects, chewing resulted in a bilateral increase in blood oxygenation level-dependent (BOLD) signals in the sensorimotor cortex, supplementary motor area, insula, thalamus, and cerebellum. In addition, in the first three regions, chewing of moderately hard gum produced stronger BOLD signals than the chewing of hard gum. However, the signal was higher in the cerebellum and not significant in the thalamus, respectively. These results suggest that chewing causes regional increases in brain neuronal activities which are related to biting force.

  10. Design and implementation of a project-based active/cooperative engineering design course for freshmen

    NASA Astrophysics Data System (ADS)

    Abdulaal, R. M.; Al-Bahi, A. M.; Soliman, A. Y.; Iskanderani, F. I.

    2011-08-01

    A project-based active/cooperative design course is planned, implemented, assessed and evaluated to achieve several desired engineering outcomes. The course allows freshman-level students to gain professional hands-on engineering design experience through an opportunity to practise teamwork, quality principles, communication skills, life-long learning, realistic constraints and awareness of current domestic and global challenges. Throughout successive design reports and in-class assignments, the students are required by the end of the semester to communicate, clearly and concisely, the details of their design both orally and in writing through a functional artefact/prototype, a design notebook, an A0 project poster and a final oral presentation. In addition to these direct assessment tools, several indirect measures are used to ensure triangulation. Assignments are based on customer expectations using a detailed checklist. This paper shows the direct and indirect assessment tools that indicated a high level of achievement of course learning outcomes and a high level of student satisfaction.

  11. Towards a new LHC interaction region design for a luminosity upgrade

    SciTech Connect

    James Strait et al.

    2003-05-29

    After the LHC operates for several years at nominal parameters, it will be necessary to upgrade it for higher luminosity. Replacing the low-{beta} insertions with a higher performance design based on advanced superconducting magnets is one of the most straightforward steps in this direction. Preliminary studies show that, with magnet technology that is expected to be developed by early in the next decade, a factor of 2 to 5 reduction in {beta}* could be achieved with new insertions, as part of an upgrade aimed at a factor of 10 luminosity increase. In this paper we survey several possible second generation LHC interaction regions designs, which address the expected limitations on LHC performance imposed by the baseline insertions.

  12. Design, synthesis and structure-activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities.

    PubMed

    Cardoso, Marcos Veríssimo de Oliveira; Moreira, Diogo Rodrigo Magalhães; Oliveira Filho, Gevanio Bezerra; Cavalcanti, Suellen Melo Tiburcio; Coelho, Lucas Cunha Duarte; Espíndola, José Wanderlan Pontes; Gonzalez, Laura Rubio; Rabello, Marcelo Montenegro; Hernandes, Marcelo Zaldini; Ferreira, Paulo Michel Pinheiro; Pessoa, Cláudia; Alberto de Simone, Carlos; Guimarães, Elisalva Teixeira; Soares, Milena Botelho Pereira; Leite, Ana Cristina Lima

    2015-01-01

    The present work reports the synthesis and evaluation of the antitumour and immunomodulatory properties of new phthalimides derivatives designed to explore molecular hybridization and bioisosterism approaches between thalidomide, thiosemicarbazone, thiazolidinone and thiazole series. Twenty-seven new molecules were assessed for their immunosuppressive effect toward TNFα, IFNγ, IL-2 and IL-6 production and antiproliferative activity. The best activity profile was observed for the (6a-f) series, which presents phthalyl and thiazolidinone groups.

  13. Analysis of the characteristics of solar oscillation modes in active regions

    NASA Astrophysics Data System (ADS)

    Rabello-Soares, M. Cristina; Bogart, Richard S.; Basu, Sarbani

    2008-10-01

    We analyze the characteristics of high-degree solar acoustic modes in the vicinity of magnetic active regions and compare with those of magnetically quiet regions at the same latitude and at nearly the same time. We applied ring-diagram analysis to GONG+ and MDI data, using the 13-parameter mode-fitting model of Basu & Antia [1]. We explore the correlations of variations in mode frequencies, amplitudes, widths, and asymmetries with the total magnetic flux of the analyzed regions.

  14. Region and site specific design guidelines for the northeastern Venezuela development

    SciTech Connect

    Gajardo, E.; Paga, M.; Sully, J.P.

    1996-12-31

    Several site specific studies were performed for the northeastern Venezuelan offshore development in order to determine the environmental parameters for the engineering design. The geotechnical parameters were obtained from the analysis of the soil borings, in situ tests and the high resolution seismic surveys. An evaluation of the seismic hazard was done, based on a detailed neotectonic study, the compilation of historical and instrumental seismological information, and an attenuation relationship developed for the studied area. Seismic response analyses were performed using the seismic parameters and dynamic characteristics obtained form the soil borings and in situ tests of shear waves. The met-ocean design loads of the local conditions were obtained from mathematical modeling based on in situ and regional measurements. This study defines the platforms design conditions based on a probabilistic reliability approach and it has been used, among others, as a basis for the earthquake design guidelines proposed by the International Standards Organization. A sensitivity analysis was performed starting from the uncertainties of all the input parameters, in order to obtain the best estimate average design spectrum and associated coefficient of variability. The specific approach was to maintain the same safety index adopted by API RP2A code, with a bias modification factor that relates the site nominal spectra with the spectral acceleration that would be used in order to satisfy the API requirements. The results of this approach make possible the use of site specific detailed environmental data and the proven standard procedures established on the API RP2 codes, with significant cost reduction in terms of both platform and foundation design. The considerable amount of tectonic, seismological, and geotechnical information was the principal factor allowing the above methodology.

  15. Complex active regions as the main source of extreme and large solar proton events

    NASA Astrophysics Data System (ADS)

    Ishkov, V. N.

    2013-12-01

    A study of solar proton sources indicated that solar flare events responsible for ≥2000 pfu proton fluxes mostly occur in complex active regions (CARs), i.e., in transition structures between active regions and activity complexes. Different classes of similar structures and their relation to solar proton events (SPEs) and evolution, depending on the origination conditions, are considered. Arguments in favor of the fact that sunspot groups with extreme dimensions are CARs are presented. An analysis of the flare activity in a CAR resulted in the detection of "physical" boundaries, which separate magnetic structures of the same polarity and are responsible for the independent development of each structure.

  16. Design Strategies for Redox Active Metalloenzymes: Applications in Hydrogen Production.

    PubMed

    Alcala-Torano, R; Sommer, D J; Bahrami Dizicheh, Z; Ghirlanda, G

    2016-01-01

    The last decades have seen an increased interest in finding alternative means to produce renewable fuels in order to satisfy the growing energy demands and to minimize environmental impact. Nature can serve as an inspiration for development of these methodologies, as enzymes are able to carry out a wide variety of redox processes at high efficiency, employing a wide array of earth-abundant transition metals to do so. While it is well recognized that the protein environment plays an important role in tuning the properties of the different metal centers, the structure/function relationships between amino acids and catalytic centers are not well resolved. One specific approach to study the role of proteins in both electron and proton transfer is the biomimetic design of redox active peptides, binding organometallic clusters in well-understood protein environments. Here we discuss different strategies for the design of peptides incorporating redox active FeS clusters, [FeFe]-hydrogenase organometallic mimics, and porphyrin centers into different peptide and protein environments in order to understand natural redox enzymes. PMID:27586342

  17. Design and test of three active flutter suppression controllers

    NASA Technical Reports Server (NTRS)

    Christhilf, David M.; Waszak, Martin R.; Adams, William M.; Srinathkumar, S.; Mukhopadhyay, Vivek

    1991-01-01

    Three flutter suppression control law design techniques are presented. Each uses multiple control surfaces and/or sensors. The first uses linear combinations of several accelerometer signals together with dynamic compensation to synthesize the modal rate of the critical mode for feedback to distributed control surfaces. The second uses traditional tools (pole/zero loci and Nyquist diagrams) to develop a good understanding of the flutter mechanism and produce a controller with minimal complexity and good robustness to plant uncertainty. The third starts with a minimum energy Linear Quadratic Gaussian controller, applies controller order reduction, and then modifies weight and noise covariance matrices to improve multi-variable robustness. The resulting designs were implemented digitally and tested subsonically on the Active Flexible Wing (AFW) wind tunnel model. Test results presented here include plant characteristics, maximum attained closed-loop dynamic pressure, and Root Mean Square control surface activity. A key result is that simultaneous symmetric and antisymmetric flutter suppression was achieved by the second control law, with a 24 percent increase in attainable dynamic pressure.

  18. Sensitivity method for integrated structure/active control law design

    NASA Technical Reports Server (NTRS)

    Gilbert, Michael G.

    1987-01-01

    The development is described of an integrated structure/active control law design methodology for aeroelastic aircraft applications. A short motivating introduction to aeroservoelasticity is given along with the need for integrated structures/controls design algorithms. Three alternative approaches to development of an integrated design method are briefly discussed with regards to complexity, coordination and tradeoff strategies, and the nature of the resulting solutions. This leads to the formulation of the proposed approach which is based on the concepts of sensitivity of optimum solutions and multi-level decompositions. The concept of sensitivity of optimum is explained in more detail and compared with traditional sensitivity concepts of classical control theory. The analytical sensitivity expressions for the solution of the linear, quadratic cost, Gaussian (LQG) control problem are summarized in terms of the linear regulator solution and the Kalman Filter solution. Numerical results for a state space aeroelastic model of the DAST ARW-II vehicle are given, showing the changes in aircraft responses to variations of a structural parameter, in this case first wing bending natural frequency.

  19. Crossing Active Faults on the Sakhalin II Onshore Pipeline Route: Analysis Methodology and Basic Design

    SciTech Connect

    Vitali, Luigino; Mattiozzi, Pierpaolo

    2008-07-08

    Twin oil (20 and 24 inch) and gas (20 and 48 inch) pipeline systems stretching 800 km are being constructed to connect offshore hydrocarbon deposits from the Sakhalin II concession in the North to an LNG plant and oil export terminal in the South of Sakhalin island. The onshore pipeline route follows a regional fault zone and crosses individual active faults at 19 locations. Sakhalin Energy, Design and Construction companies took significant care to ensure the integrity of the pipelines, should large seismic induced ground movements occur during the Operational life of the facilities. Complex investigations including the identification of the active faults, their precise location, their particular displacement values and assessment of the fault kinematics were carried out to provide input data for unique design solutions. Lateral and reverse offset displacements of 5.5 and 4.5 m respectively were determined as the single-event values for the design level earthquake (DLE)--the 1000-year return period event. Within the constraints of a pipeline route largely fixed, the underground pipeline fault crossing design was developed to define the optimum routing which would minimize stresses and strain using linepipe materials which had been ordered prior to the completion of detailed design, and to specify requirements for pipe trenching shape, materials, drainage system, etc. This Paper describes the steps followed to formulate the concept of the special trenches and the analytical characteristics of the Model.

  20. Crossing Active Faults on the Sakhalin II Onshore Pipeline Route: Analysis Methodology and Basic Design

    NASA Astrophysics Data System (ADS)

    Vitali, Luigino; Mattiozzi, Pierpaolo

    2008-07-01

    Twin oil (20 & 24 inch) and gas (20 & 48 inch) pipeline systems stretching 800 km are being constructed to connect offshore hydrocarbon deposits from the Sakhalin II concession in the North to an LNG plant and oil export terminal in the South of Sakhalin island. The onshore pipeline route follows a regional fault zone and crosses individual active faults at 19 locations. Sakhalin Energy, Design and Construction companies took significant care to ensure the integrity of the pipelines, should large seismic induced ground movements occur during the Operational life of the facilities. Complex investigations including the identification of the active faults, their precise location, their particular displacement values and assessment of the fault kinematics were carried out to provide input data for unique design solutions. Lateral and reverse offset displacements of 5.5 and 4.5 m respectively were determined as the single-event values for the design level earthquake (DLE)—the 1000-year return period event. Within the constraints of a pipeline route largely fixed, the underground pipeline fault crossing design was developed to define the optimum routing which would minimize stresses and strain using linepipe materials which had been ordered prior to the completion of detailed design, and to specify requirements for pipe trenching shape, materials, drainage system, etc. This Paper describes the steps followed to formulate the concept of the special trenches and the analytical characteristics of the Model.

  1. Regional Climate Responses To Planetary-Scale Geoengineering Activities, as Modeled Using climateprediction.net/HadCM3L

    NASA Astrophysics Data System (ADS)

    Ricke, K.

    2009-12-01

    Concerns that climate mitigation is occurring too slowly, or that there may be a rapid "climate surprise," have lead to renewed dialogue within the scientific community about cooling the planet through geoengineering, specifically stratospheric albedo modification (SAM). There is little consensus about regional hydrological effects of such activities despite a recent spate of climate modeling studies looking at its potential impacts. Here we present the results from one large-ensemble experiment that used Hadley Centre Coupled Model, version 3 with reduced resolution over the ocean (HadCM3L), implemented through climateprediction.net. The analysis examines 54 globally-uniform stratospheric optical depth modification scenarios designed to stabilize global temperatures under SRES A1B. We present normalized regional temperature anomalies versus normalized regional precipitation and subsurface runoff anomalies (for example, see Figure 1) and the results of regression analyses to quantify the relationships between level of stratospheric optical property modification (i.e., geoengineering) and regional hydrology. Results show that while such shortwave compensations for longwave anthropogenic forcings does generally return regional climates to closer to their baseline climate states than the no-geoengineering, business-as-usual scenarios, the magnitudes and sensitivities of regional responses to this type of activity, as modeled in HadCM3L, are highly variable. Regions, such as Eastern China and India, migrate away from their baseline climate states in different ways, illustrating the impossibility of simultaneous stabilization of regional climates. The linearity of the effect of incrementally increasing stratospheric optical depth also varies regionally. Figure 1: Normalized regional temperature and precipitation anomalies (<2020s>-<1990s> and <2070s>-<1990s>) in units of baseline standard deviations for each region). Each grayscale point in-series near the origin

  2. Using the Global Navigation Satellite System (GNSS) data for Hazard Estimation in Some Active Regions in Egypt

    NASA Astrophysics Data System (ADS)

    Sayed Mohamed, Abdel-Monem

    2016-07-01

    Egypt rapidly growing development is accompanied by increasing levels of standard living particular in its urban areas. However, there is a limited experience in quantifying the sources of risk management in Egypt and in designing efficient strategies to keep away serious impacts of earthquakes. From the historical point of view and recent instrumental records, there are some seismo-active regions in Egypt, where some significant earthquakes had occurred in different places. The special tectonic features in Egypt: Aswan, Greater Cairo, Red Sea and Sinai Peninsula regions are the territories of a high seismic risk, which have to be monitored by up-to date technologies. The investigations of the seismic events and interpretations led to evaluate the seismic hazard for disaster prevention and for the safety of the dense populated regions and the vital national projects as the High Dam. In addition to the monitoring of the recent crustal movements, the most powerful technique of satellite geodesy GNSS are used where geodetic networks are covering such seismo-active regions. The results from the data sets are compared and combined in order to determine the main characteristics of the deformation and hazard estimation for specified regions. The final compiled output from the seismological and geodetic analysis threw lights upon the geodynamical regime of these seismo-active regions and put Aswan and Greater Cairo under the lowest class according to horizontal crustal strains classifications. This work will serve a basis for the development of so-called catastrophic models and can be further used for catastrophic risk management. Also, this work is trying to evaluate risk of large catastrophic losses within the important regions including the High Dam, strategic buildings and archeological sites. Studies on possible scenarios of earthquakes and losses are a critical issue for decision making in insurance as a part of mitigation measures.

  3. HARPs: Tracked Active Region Patch Data Product from SDO/HMI

    NASA Astrophysics Data System (ADS)

    Turmon, M.; Hoeksema, J. T.; Sun, X.; Bobra, M.

    2012-12-01

    We describe an HMI data product consisting of tracked magnetic features on the scale of solar active regions, abbreviated HARPs (HMI Active Region Patches). The HARP data series has been helpful for subsetting individual active regions, for development of near-real-time (NRT) space weather indices for individual active regions, and for defining closed magnetic structures for computationally-intensive algorithms like vector field disambiguation. The data series builds upon the 720s cadence activity masks, which identify large-scale instantaneously-observed magnetic features. Using these masks as a starting point, large spatially-coherent structures are identified using convolution with a longitudinally-extended kernel on a spherical domain. The resulting set of identified regions is then tracked from image to image. The metric for inter-image association is area of overlap between the best current estimate of AR location, as predicted by temporally extrapolating each currently tracked object, and the set of instantaneously-observed magnetic structures. Once completed tracks have been extracted, they are made into a standardized HARP data series by finding the smallest constant-angular-velocity box, of constant width in latitude and longitude, that encompasses all appearances of the active region. This data product is currently available, in definitive and near-real-time forms, with accompanying region-strength, location, and NOAA-AR metadata, on HMI's Joint Science Operations Center (JSOC) data portal.; HARP outlines for three days (2001 February 14, 15, and 16, 00:00 TAI, flipped N-S, selected from the 12-minute cadence original data product). HARPs are shown in the same color (some colors repeated) with a thin white box surrounding each HARP. HARPs are tracked and associated from image to image. HARPs, such as the yellow one in the images above, need not be connected regions. Merges and splits, such as the light blue region, are accounted for automatically.

  4. Geodetic Network Design and Optimization on the Active Tuzla Fault (Izmir, Turkey) for Disaster Management

    PubMed Central

    Halicioglu, Kerem; Ozener, Haluk

    2008-01-01

    Both seismological and geodynamic research emphasize that the Aegean Region, which comprises the Hellenic Arc, the Greek mainland and Western Turkey is the most seismically active region in Western Eurasia. The convergence of the Eurasian and African lithospheric plates forces a westward motion on the Anatolian plate relative to the Eurasian one. Western Anatolia is a valuable laboratory for Earth Science research because of its complex geological structure. Izmir is a large city in Turkey with a population of about 2.5 million that is at great risk from big earthquakes. Unfortunately, previous geodynamics studies performed in this region are insufficient or cover large areas instead of specific faults. The Tuzla Fault, which is aligned trending NE–SW between the town of Menderes and Cape Doganbey, is an important fault in terms of seismic activity and its proximity to the city of Izmir. This study aims to perform a large scale investigation focusing on the Tuzla Fault and its vicinity for better understanding of the region's tectonics. In order to investigate the crustal deformation along the Tuzla Fault and Izmir Bay, a geodetic network has been designed and optimizations were performed. This paper suggests a schedule for a crustal deformation monitoring study which includes research on the tectonics of the region, network design and optimization strategies, theory and practice of processing. The study is also open for extension in terms of monitoring different types of fault characteristics. A one-dimensional fault model with two parameters – standard strike-slip model of dislocation theory in an elastic half-space – is formulated in order to determine which sites are suitable for the campaign based geodetic GPS measurements. Geodetic results can be used as a background data for disaster management systems.

  5. Design and Implementation of Alkali Activated Cement For Sustainable Development

    NASA Astrophysics Data System (ADS)

    Moseson, Alexander James

    Herein, progress is presented on the design and implementation of technology for sustainable development in general and international development in particular. Necessarily interdisciplinary, the work draws upon the tools and techniques of Mechanical, Materials, and Civil Engineering; and History & Politics. The work was conducted along two paths, the first being the theory and methodology of sustainable development. A flexible design and dissemination framework was developed, Technology Seeding, defined as: development by the transfer and participatory adaptation of appropriate proven conceptual designs. The methodology was developed in part through two case studies which implemented, respectively, wood-turning lathes in Tanzania and upland rice planters in Thailand. The second path is the design and investigation of alkali-activated cements (AACs) for practical use. Those developed herein, for US markets, comprise ground granulated blast furnace slag, soda ash (sodium carbonate), and up to 68 wt.% granular limestone. Mixture Design of Experiment (DOE) was utilized to guide empirical and theoretical analysis of performance (e.g. compressive strength), economic & ecological aspects (e.g. cost, CO2 production, energy consumption), and chemistry (e.g. Rietveld analysis of x-ray diffractograms). Models were derived to understand the impact of mix design on performance and for optimization. Successful formulations are hydraulic and cure at room temperature, with strengths as high as 41 MPa at 3 days and 65 MPa at 28 days. Some of these formulations, compared to OPC, are competitive in performance, reduce cost by up to 40%, and reduce both CO2 production and energy consumption by up to 97%. Major chemical products include calcium silicate hydrates / calcium aluminum silicate hydrates (C-(A)-S-H), gaylussite, and calcite (both newly formed and remaining from limestone). Calcite/dolomite and C-(A)-S-H both contribute to strength. A fraction of the limestone is consumed

  6. Teaching with Data: Resources for Designing Effective Activities

    NASA Astrophysics Data System (ADS)

    Manduca, C. A.; Mogk, D. W.

    2004-12-01

    Faculty and teachers understand the power of engaging students directly with data and are tremendously enthusiastic about the possibilities of incorporating data-rich activities in their teaching. This enthusiasm reflects the desire to empower students to solve problems, to place learning in an exciting and authentic real world context that motivates learning, and to illuminate students' understanding of the nature of science. Data-rich activities provide abundant opportunities to motivate students to engage in learning, to integrate learning of facts and skills, and to build on prior knowledge. These are all factors that are identified by research as fundamental to the learning process (How People Learn, 1999, NRC). Data-rich activities can place learning in a context that enhances students' ability to use information in new situations. Seismological data offer many opportunities due to students' familiarity with and interest in earthquakes, and its use to probe the internal structure of the Earth. Three of the most challenging aspects of teaching with data are 1) presenting data with analysis tools that can be quickly mastered, 2) designing learning activities to match the level of student expertise with data analysis and critical thinking, and 3) creating assessments that capture learning beyond factual recall. The Using Data in the Classroom website (serc.carleton.edu/usingdata) helps faculty excel at teaching with data by providing easy access to a wide range of data, discussion of the ways in which data can be effectively used in the classroom, examples of data-rich activities at a variety of educational levels across a range of geoscience topics, and references to pedagogic information. The Earth Exploration Toolbook (serc.Carleton.edu/eet) supports teachers' use of particular datasets and tools by providing step-by-step instructions in the context of an example. The Investigating Earthquakes chapter focuses specifically on use of GIS to analyze USGS

  7. Regional activation within the vastus medialis in stimulated and voluntary contractions.

    PubMed

    Gallina, Alessio; Ivanova, Tanya D; Garland, S Jayne

    2016-08-01

    This study examined the contribution of muscle fiber orientation at different knee angles to regional activation identified with high-density surface electromyography (HDsEMG). Monopolar HDsEMG signals were collected using a grid of 13 × 5 electrodes placed over the vastus medialis (VM). Intramuscular electrical stimulation was used to selectively activate two regions within VM. The distribution of EMG responses to stimulation was obtained by calculating the amplitude of the compound action potential for each channel; the position of the peak amplitude was tracked across knee angles to describe shifts of the active muscle regions under the electrodes. In a separate experiment, regional activation was investigated in 10 knee flexion-extension movements against a fixed resistance. Intramuscular stimulation of different VM regions resulted in clear differences in amplitude distribution along the columns of the electrode grid (P < 0.001); changes in knee angle resulted in consistent shifts along the rows (P < 0.01) and negligible shifts along the columns of the electrode grid. Regional VM activation was identified in dynamic movement, with distal shifts of the EMG distribution in the eccentric phase of the movement (P < 0.05) and at more flexed knee angles (P < 0.05). HDsEMG was used to describe regional activation across the VM that was not attributable to anatomic factors. Changes in muscle fiber orientation associated with knee joint angle mainly influence the amplitude distribution along the fiber direction. Future studies are needed to understand possible functional roles for regional activation within the VM in dynamic tasks. PMID:27365281

  8. Regional activation of rapid onset vasodilatation in mouse skeletal muscle: regulation through α-adrenoreceptors.

    PubMed

    Moore, Alex W; Bearden, Shawn E; Segal, Steven S

    2010-09-01

    Exercise onset entails motor unit recruitment and the initiation of vasodilatation. Dilatation can ascend the arteriolar network to encompass proximal feed arteries but is opposed by sympathetic nerve activity, which promotes vasoconstriction and inhibits ascending vasodilatation through activating α-adrenoreceptors. Whereas contractile activity can antagonize sympathetic vasoconstriction, more subtle aspects of this interaction remain to be defined. We tested the hypothesis that constitutive activation of α-adrenoreceptors governs blood flow distribution within individual muscles. The mouse gluteus maximus muscle (GM) consists of Inferior and Superior regions. Each muscle region is supplied by its own motor nerve and feed artery with an anastomotic arteriole (resting diameter 25 microm) that spans both muscle regions. In anaesthetized male C57BL/6J mice (3-5 months old), the GM was exposed and superfused with physiological saline solution (35 degrees C; pH 7.4). Stimulating the inferior gluteal motor nerve (0.1 ms pulse, 100 Hz for 500 ms) evoked a brief tetanic contraction and produced rapid (<1 s) onset vasodilatation (ROV; diameter change, 10 +/- 1 μm) of the anastomotic arteriole along the active (Inferior) muscle region but not along the inactive (Superior) region (n = 8). In contrast, microiontophoresis of acetylcholine (1 μm micropipette tip, 1 μA, 500 ms) initiated dilatation that travelled along the anastomotic arteriole from the Inferior into the Superior muscle region (diameter change, 5 +/- 2 μm). Topical phentolamine (1 μm) had no effect on resting diameter but this inhibition of α-adrenoreceptors enabled ROV to spread along the anastomotic arteriole into the inactive muscle region (dilatation, 7 +/- 1 μm; P < 0.05), where remote dilatation to acetylcholine then doubled (P < 0.05). These findings indicate that constitutive activation of α-adrenoreceptors in skeletal muscle can restrict the spread of dilatation within microvascular resistance

  9. MAG4 versus alternative techniques for forecasting active region flare productivity

    PubMed Central

    Falconer, David A; Moore, Ronald L; Barghouty, Abdulnasser F; Khazanov, Igor

    2014-01-01

    MAG4 is a technique of forecasting an active region's rate of production of major flares in the coming few days from a free magnetic energy proxy. We present a statistical method of measuring the difference in performance between MAG4 and comparable alternative techniques that forecast an active region's major-flare productivity from alternative observed aspects of the active region. We demonstrate the method by measuring the difference in performance between the “Present MAG4” technique and each of three alternative techniques, called “McIntosh Active-Region Class,” “Total Magnetic Flux,” and “Next MAG4.” We do this by using (1) the MAG4 database of magnetograms and major flare histories of sunspot active regions, (2) the NOAA table of the major-flare productivity of each of 60 McIntosh active-region classes of sunspot active regions, and (3) five technique performance metrics (Heidke Skill Score, True Skill Score, Percent Correct, Probability of Detection, and False Alarm Rate) evaluated from 2000 random two-by-two contingency tables obtained from the databases. We find that (1) Present MAG4 far outperforms both McIntosh Active-Region Class and Total Magnetic Flux, (2) Next MAG4 significantly outperforms Present MAG4, (3) the performance of Next MAG4 is insensitive to the forward and backward temporal windows used, in the range of one to a few days, and (4) forecasting from the free-energy proxy in combination with either any broad category of McIntosh active-region classes or any Mount Wilson active-region class gives no significant performance improvement over forecasting from the free-energy proxy alone (Present MAG4). Key Points Quantitative comparison of performance of pairs of forecasting techniques Next MAG4 forecasts major flares more accurately than Present MAG4 Present MAG4 forecast outperforms McIntosh AR Class and total magnetic flux PMID:26213517

  10. A Search for Coriolis Forces Acting on Tilt in Bipolar Active Regions

    NASA Astrophysics Data System (ADS)

    McClintock, B. H.

    2013-12-01

    Bipolar active regions tend to be tilted with respect to the East - West equator of the Sun in accordance with Joy's law that describes the average tilt angle as a function of latitude. As individual bipolar active regions emerge, tilt angles vary with time. Data collected by the Helioseismic and Magnetic Imager aboard the Solar Dynamic Observatory at a higher cadence than previous data allow for a more continuous analysis of emerging regions over their lifetimes. It is theorized that rising magnetic flux-tubes, which emerge as active regions on the surface, are tilted by Coriolis forces acting on the retrograde flow inside the tubes. We will search for and measure any decrease in tilt near the end of emergence, as an indicator of Coriolis forces ending.

  11. MAGNETIC FIELD TOPOLOGY AND THE THERMAL STRUCTURE OF THE CORONA OVER SOLAR ACTIVE REGIONS

    SciTech Connect

    Schrijver, Carolus J.; DeRosa, Marc L.; Title, Alan M.

    2010-08-20

    Solar extreme ultraviolet (EUV) images of quiescent active-region coronae are characterized by ensembles of bright 1-2 MK loops that fan out from select locations. We investigate the conditions associated with the formation of these persistent, relatively cool, loop fans within and surrounding the otherwise 3-5 MK coronal environment by combining EUV observations of active regions made with TRACE with global source-surface potential-field models based on the full-sphere photospheric field from the assimilation of magnetograms that are obtained by the Michelson Doppler Imager (MDI) on SOHO. We find that in the selected active regions with largely potential-field configurations these fans are associated with (quasi-)separatrix layers (QSLs) within the strong-field regions of magnetic plage. Based on the empirical evidence, we argue that persistent active-region cool-loop fans are primarily related to the pronounced change in connectivity across a QSL to widely separated clusters of magnetic flux, and confirm earlier work that suggested that neither a change in loop length nor in base field strengths across such topological features are of prime importance to the formation of the cool-loop fans. We discuss the hypothesis that a change in the distribution of coronal heating with height may be involved in the phenomenon of relatively cool coronal loop fans in quiescent active regions.

  12. {open_quotes}Radon{close_quotes} - the system of Soviet designed regional waste management facilities

    SciTech Connect

    Horak, W.C.; Reisman, A.; Purvis, E.E. III

    1997-07-01

    The Soviet Union established a system of specialized regional facilities to dispose of radioactive waste generated by sources other than the nuclear fuel cycle. The system had 16 facilities in Russia, 5 in Ukraine, one in each of the other CIS states, and one in each of the Baltic Republics. These facilities are still being used. The major generators of radioactive waste they process these are research and industrial organizations, medical and agricultural institution and other activities not related to nuclear power. Waste handled by these facilities is mainly beta- and gamma-emitting nuclides with half lives of less than 30 years. The long-lived and alpha-emitting isotopic content is insignificant. Most of the radwaste has low and medium radioactivity levels. The facilities also handle spent radiation sources, which are highly radioactive and contain 95-98 percent of the activity of all the radwaste buried at these facilities.

  13. 50 CFR 217.151 - Specified activity and specified geographical region.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... activity and specified geographical region. (a) Regulations in this subpart apply only to Port Dolphin Energy LLC (Port Dolphin) and those persons it authorizes to conduct activities on its behalf for the... incidental to construction and operation of the Port Dolphin Deepwater Port (Port). (b) The taking of...

  14. 50 CFR 217.151 - Specified activity and specified geographical region.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... activity and specified geographical region. (a) Regulations in this subpart apply only to Port Dolphin Energy LLC (Port Dolphin) and those persons it authorizes to conduct activities on its behalf for the... incidental to construction and operation of the Port Dolphin Deepwater Port (Port). (b) The taking of...

  15. 50 CFR 217.170 - Specified activity and specified geographical region.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Operation and Maintenance of the Neptune Liquefied Natural Gas Facility Off Massachusetts § 217.170 Specified activity and specified geographical region. (a) Regulations in this subpart apply only to Neptune LNG LLC (Neptune) and those persons it authorizes to conduct activities on its behalf for the...

  16. 50 CFR 217.170 - Specified activity and specified geographical region.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Operation and Maintenance of the Neptune Liquefied Natural Gas Facility Off Massachusetts § 217.170 Specified activity and specified geographical region. (a) Regulations in this subpart apply only to Neptune LNG LLC (Neptune) and those persons it authorizes to conduct activities on its behalf for the...

  17. 50 CFR 217.170 - Specified activity and specified geographical region.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Operation and Maintenance of the Neptune Liquefied Natural Gas Facility Off Massachusetts § 217.170 Specified activity and specified geographical region. (a) Regulations in this subpart apply only to Neptune LNG LLC (Neptune) and those persons it authorizes to conduct activities on its behalf for the...

  18. 50 CFR 217.170 - Specified activity and specified geographical region.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Operation and Maintenance of the Neptune Liquefied Natural Gas Facility Off Massachusetts § 217.170 Specified activity and specified geographical region. (a) Regulations in this subpart apply only to Neptune LNG LLC (Neptune) and those persons it authorizes to conduct activities on its behalf for the...

  19. Regional Quality Assurance Activity in Higher Education in Southeast Asia: Its Characteristics and Driving Forces

    ERIC Educational Resources Information Center

    Umemiya, Naoki

    2008-01-01

    This article analyses the characteristics and driving forces of regional quality assurance activity in Southeast Asia, which has been actively promoted in recent years by the ASEAN University Network, an organisation for higher education under the auspices of the Association of Southeast Asian Nations (ASEAN). There are now more collaborative…

  20. Regional brain activation during meditation shows time and practice effects: an exploratory FMRI study.

    PubMed

    Baron Short, E; Kose, Samet; Mu, Qiwen; Borckardt, Jeffery; Newberg, Andrew; George, Mark S; Kozel, F Andrew

    2010-03-01

    Meditation involves attentional regulation and may lead to increased activity in brain regions associated with attention such as dorsal lateral prefrontal cortex (DLPFC) and anterior cingulate cortex (ACC). Using functional magnetic resonance imaging, we examined whether DLPFC and ACC were activated during meditation. Subjects who meditate were recruited and scanned on a 3.0 Tesla scanner. Subjects meditated for four sessions of 12 min and performed four sessions of a 6 min control task. Individual and group t-maps were generated of overall meditation response versus control response and late meditation response versus early meditation response for each subject and time courses were plotted. For the overall group (n = 13), and using an overall brain analysis, there were no statistically significant regional activations of interest using conservative thresholds. A region of interest analysis of the entire group time courses of DLPFC and ACC were statistically more active throughout meditation in comparison to the control task. Moreover, dividing the cohort into short (n = 8) and long-term (n = 5) practitioners (>10 years) revealed that the time courses of long-term practitioners had significantly more consistent and sustained activation in the DLPFC and the ACC during meditation versus control in comparison to short-term practitioners. The regional brain activations in the more practised subjects may correlate with better sustained attention and attentional error monitoring. In summary, brain regions associated with attention vary over the time of a meditation session and may differ between long- and short-term meditation practitioners.

  1. Medical Image Segmentation Based on a Hybrid Region-Based Active Contour Model

    PubMed Central

    Liu, Tingting; Xu, Haiyong; Liu, Zhen; Zhao, Yiming; Tian, Wenzhe

    2014-01-01

    A novel hybrid region-based active contour model is presented to segment medical images with intensity inhomogeneity. The energy functional for the proposed model consists of three weighted terms: global term, local term, and regularization term. The total energy is incorporated into a level set formulation with a level set regularization term, from which a curve evolution equation is derived for energy minimization. Experiments on some synthetic and real images demonstrate that our model is more efficient compared with the localizing region-based active contours (LRBAC) method, proposed by Lankton, and more robust compared with the Chan-Vese (C-V) active contour model. PMID:25028593

  2. Design of a novel chimeric tissue plasminogen activator with favorable Vampire bat plasminogen activator properties.

    PubMed

    Kazemali, MohammadReza; Majidzadeh-A, Keivan; Sardari, Soroush; Saadatirad, Amir Hossein; Khalaj, Vahid; Zarei, Najmeh; Barkhordari, Farzaneh; Adeli, Ahmad; Mahboudi, Fereidoun

    2014-12-01

    Fibrinolytic agents are widely used in treatment of the thromboembolic disorders. The new generations like recombinant tissue plasminogen activator (t-PA, alteplase) are not showing promising results in clinical practice in spite of displaying specific binding to fibrin in vitro. Vampire bat plasminogen activator (b-PA) is a plasminogen activator with higher fibrin affinity and specificity in comparison to t-PA resulting in reduced probability of hemorrhage. b-PA is also resistant to plasminogen activator inhibitor-1 (PAI-1) showing higher half-life compared to other variants of t-PA. However, its non-human origin was a driving force to design a human t-PA with favorable properties of b-PA. In the present study, we designed a chimeric t-PA with desirable b-PA properties and this new molecule was called as CT-b. The construct was prepared through kringle 2 domain removal and replacement of t-PA finger domain with b-PA one. In addition, the KHRR sequence at the initial part of protease domain was replaced by four alanine residues. The novel construct was integrated in Pichia pastoris genome by electroporation. Catalytic activity was investigated in the presence and absence of fibrin. The purified protein was analyzed by western blot. Fibrin binding and PAI resistance assays were also conducted. The activity of the recombinant protein in the presence of fibrin was 1560 times more than its activity in the absence of fibrin, showing its higher specificity to fibrin. The fibrin binding of CT-b was 1.2 fold more than t-PA. In addition, it was inhibited by PAI enzyme 44% less than t-PA. Although the presented data demonstrate a promising in vitro activity, more in vivo studies are needed to confirm the therapeutic advantage of this novel plasminogen activator.

  3. Design of a novel chimeric tissue plasminogen activator with favorable Vampire bat plasminogen activator properties.

    PubMed

    Kazemali, MohammadReza; Majidzadeh-A, Keivan; Sardari, Soroush; Saadatirad, Amir Hossein; Khalaj, Vahid; Zarei, Najmeh; Barkhordari, Farzaneh; Adeli, Ahmad; Mahboudi, Fereidoun

    2014-12-01

    Fibrinolytic agents are widely used in treatment of the thromboembolic disorders. The new generations like recombinant tissue plasminogen activator (t-PA, alteplase) are not showing promising results in clinical practice in spite of displaying specific binding to fibrin in vitro. Vampire bat plasminogen activator (b-PA) is a plasminogen activator with higher fibrin affinity and specificity in comparison to t-PA resulting in reduced probability of hemorrhage. b-PA is also resistant to plasminogen activator inhibitor-1 (PAI-1) showing higher half-life compared to other variants of t-PA. However, its non-human origin was a driving force to design a human t-PA with favorable properties of b-PA. In the present study, we designed a chimeric t-PA with desirable b-PA properties and this new molecule was called as CT-b. The construct was prepared through kringle 2 domain removal and replacement of t-PA finger domain with b-PA one. In addition, the KHRR sequence at the initial part of protease domain was replaced by four alanine residues. The novel construct was integrated in Pichia pastoris genome by electroporation. Catalytic activity was investigated in the presence and absence of fibrin. The purified protein was analyzed by western blot. Fibrin binding and PAI resistance assays were also conducted. The activity of the recombinant protein in the presence of fibrin was 1560 times more than its activity in the absence of fibrin, showing its higher specificity to fibrin. The fibrin binding of CT-b was 1.2 fold more than t-PA. In addition, it was inhibited by PAI enzyme 44% less than t-PA. Although the presented data demonstrate a promising in vitro activity, more in vivo studies are needed to confirm the therapeutic advantage of this novel plasminogen activator. PMID:25442953

  4. Venezuelan Equine Encephalitis Virus Activity in the Gulf Coast Region of Mexico, 2003–2010

    PubMed Central

    Adams, A. Paige; Navarro-Lopez, Roberto; Ramirez-Aguilar, Francisco J.; Lopez-Gonzalez, Irene; Leal, Grace; Flores-Mayorga, Jose M.; Travassos da Rosa, Amelia P. A.; Saxton-Shaw, Kali D.; Singh, Amber J.; Borland, Erin M.; Powers, Ann M.; Tesh, Robert B.; Weaver, Scott C.; Estrada-Franco, Jose G.

    2012-01-01

    Venezuelan equine encephalitis virus (VEEV) has been the causative agent for sporadic epidemics and equine epizootics throughout the Americas since the 1930s. In 1969, an outbreak of Venezuelan equine encephalitis (VEE) spread rapidly from Guatemala and through the Gulf Coast region of Mexico, reaching Texas in 1971. Since this outbreak, there have been very few studies to determine the northward extent of endemic VEEV in this region. This study reports the findings of serologic surveillance in the Gulf Coast region of Mexico from 2003–2010. Phylogenetic analysis was also performed on viral isolates from this region to determine whether there have been substantial genetic changes in VEEV since the 1960s. Based on the findings of this study, the Gulf Coast lineage of subtype IE VEEV continues to actively circulate in this region of Mexico and appears to be responsible for infection of humans and animals throughout this region, including the northern State of Tamaulipas, which borders Texas. PMID:23133685

  5. Active noise control: A tutorial for HVAC designers

    SciTech Connect

    Gelin, L.J.

    1997-08-01

    This article will identify the capabilities and limitations of ANC in its application to HVAC noise control. ANC can be used in ducted HVAC systems to cancel ductborne, low-frequency fan noise by injecting sound waves of equal amplitude and opposite phase into an air duct, as close as possible to the source of the unwanted noise. Destructive interference of the fan noise and injected noise results in sound cancellation. The noise problems that it solves are typically described as rumble, roar or throb, all of which are difficult to address using traditional noise control methods. This article will also contrast the use of active against passive noise control techniques. The main differences between the two noise control measures are acoustic performance, energy consumption, and design flexibility. The article will first present the fundamentals and basic physics of ANC. The application to real HVAC systems will follow.

  6. Module Design, Materials, and Packaging Research Team: Activities and Capabilities

    SciTech Connect

    McMahon, T. J.; del Cueto, J.; Glick, S.; Jorgensen, G.; Kempe, M.; Kennedy, C.; Pern, J.; Terwilliger, K

    2005-01-01

    Our team activities are directed at improving PV module reliability by incorporating new, more effective, and less expensive packaging materials and techniques. New and existing materials or designs are evaluated before and during accelerated environmental exposure for the following properties: (1) Adhesion and cohesion: peel strength and lap shear. (2) Electrical conductivity: surface, bulk, interface and transients. (3) Water vapor transmission: solubility and diffusivity. (4) Accelerated weathering: ultraviolet, temperature, and damp heat tests. (5) Module and cell failure diagnostics: infrared imaging, individual cell shunt characterization, coring. (6) Fabrication improvements: SiOxNy barrier coatings and enhanced wet adhesion. (7) Numerical modeling: Moisture ingress/egress, module and cell performance, and cell-to-frame leakage current. (8) Rheological properties of polymer encapsulant and sheeting materials. Specific examples will be described.

  7. MAG4 versus Alternative Techniques for Forecasting Active-Region Flare Productivity

    NASA Astrophysics Data System (ADS)

    Falconer, David; Moore, Ronald L.; Barghouty, Abdulnasser F; Khazanov, Igor

    2014-06-01

    MAG4 is a technique of forecasting an active region's rate of production of major flares in the coming few days from a free-magnetic-energy proxy. We present a statistical method of measuring the difference in performance between MAG4 and comparable alternative techniques that forecast an active region’s major-flare productivity from alternative observed aspects of the active region. We demonstrate the method by measuring the difference in performance between the “Present MAG4” technique and each of three alternative techniques, called “McIntosh Active-Region Class,” “Total Magnetic Flux,” and “Next MAG4.” We do this by using (1) the MAG4 database of magnetograms and major-flare histories of sunspot active regions, (2) the NOAA table of the major-flare productivity of each of 60 McIntosh active-region classes of sunspot active regions, and (3) five technique-performance metrics (Heidke Skill Score, True Skill Score, Percent Correct, Probability of Detection, and False Alarm Rate) evaluated from 2000 random two-by-two contingency tables obtained from the databases. We find that (1) Present MAG4 far outperforms both McIntosh Active-Region Class and Total Magnetic Flux, (2) Next MAG4 significantly outperforms Present MAG4, (3) the performance of Next MAG4 is insensitive to the forward and backward temporal windows used, in the range of one to a few days, and (4) forecasting from the free-energy proxy in combination with either any broad category of McIntosh active-region classes or any Mount Wilson active-region class gives no significant performance improvement over forecasting from the free-energy proxy alone (Present MAG4). Funding for this research came from NASA’s Game Changing Development Program, Johnson Space Center’s Space Radiation Analysis Group (SRAG), and AFOSR’s Multi-University Research Initiative. In particular, funding was facilitated by Dr. Dan Fry (NASA-JSC) and David Moore (NASA-LaRC).

  8. Design of Responsive and Active (Soft) Materials Using Liquid Crystals.

    PubMed

    Bukusoglu, Emre; Bedolla Pantoja, Marco; Mushenheim, Peter C; Wang, Xiaoguang; Abbott, Nicholas L

    2016-06-01

    Liquid crystals (LCs) are widely known for their use in liquid crystal displays (LCDs). Indeed, LCDs represent one of the most successful technologies developed to date using a responsive soft material: An electric field is used to induce a change in ordering of the LC and thus a change in optical appearance. Over the past decade, however, research has revealed the fundamental underpinnings of potentially far broader and more pervasive uses of LCs for the design of responsive soft material systems. These systems involve a delicate interplay of the effects of surface-induced ordering, elastic strain of LCs, and formation of topological defects and are characterized by a chemical complexity and diversity of nano- and micrometer-scale geometry that goes well beyond that previously investigated. As a reflection of this evolution, the community investigating LC-based materials now relies heavily on concepts from colloid and interface science. In this context, this review describes recent advances in colloidal and interfacial phenomena involving LCs that are enabling the design of new classes of soft matter that respond to stimuli as broad as light, airborne pollutants, bacterial toxins in water, mechanical interactions with living cells, molecular chirality, and more. Ongoing efforts hint also that the collective properties of LCs (e.g., LC-dispersed colloids) will, over the coming decade, yield exciting new classes of driven or active soft material systems in which organization (and useful properties) emerges during the dissipation of energy. PMID:26979412

  9. Design of Responsive and Active (Soft) Materials Using Liquid Crystals.

    PubMed

    Bukusoglu, Emre; Bedolla Pantoja, Marco; Mushenheim, Peter C; Wang, Xiaoguang; Abbott, Nicholas L

    2016-06-01

    Liquid crystals (LCs) are widely known for their use in liquid crystal displays (LCDs). Indeed, LCDs represent one of the most successful technologies developed to date using a responsive soft material: An electric field is used to induce a change in ordering of the LC and thus a change in optical appearance. Over the past decade, however, research has revealed the fundamental underpinnings of potentially far broader and more pervasive uses of LCs for the design of responsive soft material systems. These systems involve a delicate interplay of the effects of surface-induced ordering, elastic strain of LCs, and formation of topological defects and are characterized by a chemical complexity and diversity of nano- and micrometer-scale geometry that goes well beyond that previously investigated. As a reflection of this evolution, the community investigating LC-based materials now relies heavily on concepts from colloid and interface science. In this context, this review describes recent advances in colloidal and interfacial phenomena involving LCs that are enabling the design of new classes of soft matter that respond to stimuli as broad as light, airborne pollutants, bacterial toxins in water, mechanical interactions with living cells, molecular chirality, and more. Ongoing efforts hint also that the collective properties of LCs (e.g., LC-dispersed colloids) will, over the coming decade, yield exciting new classes of driven or active soft material systems in which organization (and useful properties) emerges during the dissipation of energy.

  10. A Tool for Empirical Forecasting of Major Flares, Coronal Mass Ejections, and Solar Particle Events from a Proxy of Active-Region Free Magnetic Energy

    NASA Astrophysics Data System (ADS)

    Adams, James; Barghouty, Abdulnasser; Falconer, D. A.

    This presentation describes a new forecasting tool developed for and is currently being tested by NASA's Space Radiation Analysis Group (SRAG) at JSC, which is responsible for the monitoring and forecasting of radiation exposure levels of astronauts. The new software tool is designed for the empirical forecasting of M and X-class flares, coronal mass ejections, as well as solar energetic particle events. It's algorithm is based on an empirical relationship between the various types of events rates and a proxy of the active region's free magnetic energy, determined from a data set of approximately 40,000 active-region magnetograms from approximately 1,300 active regions observed by SOHO/MDI that have known histories of flare, coronal mass ejection, and solar energetic particle event production. The new tool automatically extracts each strong-field magnetic areas from an MDI full-disk magnetogram, identifies each as an NOAA active region, and measures a proxy of the active region's free magnetic energy from the extracted magnetogram. For each active region, the empirical relationship is then used to convert the free magnetic energy proxy into an expected event rate. The expected event rate in turn can be readily converted into the probability that the active region will produce such an event in a given forward time window. Descriptions of the datasets, algorithm, and software in addition to sample applications and a validation test are presented. Further development and transition of the new tool in anticipation of SDO/HMI is briefly discussed.

  11. Genome-Based Identification of Active Prophage Regions by Next Generation Sequencing in Bacillus licheniformis DSM13

    PubMed Central

    Hertel, Robert; Rodríguez, David Pintor; Hollensteiner, Jacqueline; Dietrich, Sascha; Leimbach, Andreas; Hoppert, Michael; Liesegang, Heiko; Volland, Sonja

    2015-01-01

    Prophages are viruses, which have integrated their genomes into the genome of a bacterial host. The status of the prophage genome can vary from fully intact with the potential to form infective particles to a remnant state where only a few phage genes persist. Prophages have impact on the properties of their host and are therefore of great interest for genomic research and strain design. Here we present a genome- and next generation sequencing (NGS)-based approach for identification and activity evaluation of prophage regions. Seven prophage or prophage-like regions were identified in the genome of Bacillus licheniformis DSM13. Six of these regions show similarity to members of the Siphoviridae phage family. The remaining region encodes the B. licheniformis orthologue of the PBSX prophage from Bacillus subtilis. Analysis of isolated phage particles (induced by mitomycin C) from the wild-type strain and prophage deletion mutant strains revealed activity of the prophage regions BLi_Pp2 (PBSX-like), BLi_Pp3 and BLi_Pp6. In contrast to BLi_Pp2 and BLi_Pp3, neither phage DNA nor phage particles of BLi_Pp6 could be visualized. However, the ability of prophage BLi_Pp6 to generate particles could be confirmed by sequencing of particle-protected DNA mapping to prophage locus BLi_Pp6. The introduced NGS-based approach allows the investigation of prophage regions and their ability to form particles. Our results show that this approach increases the sensitivity of prophage activity analysis and can complement more conventional approaches such as transmission electron microscopy (TEM). PMID:25811873

  12. Validation of newly designed regional earth system model (RegESM) for Mediterranean Basin

    NASA Astrophysics Data System (ADS)

    Turuncoglu, Ufuk Utku; Sannino, Gianmaria

    2016-06-01

    We present a validation analysis of a regional earth system model system (RegESM) for the Mediterranean Basin. The used configuration of the modeling system includes two active components: a regional climate model (RegCM4) and an ocean modeling system (ROMS). To assess the performance of the coupled modeling system in representing the climate of the basin, the results of the coupled simulation (C50E) are compared to the results obtained by a standalone atmospheric simulation (R50E) as well as several observation datasets. Although there is persistent cold bias in fall and winter, which is also seen in previous studies, the model reproduces the inter-annual variability and the seasonal cycles of sea surface temperature (SST) in a general good agreement with the available observations. The analysis of the near-surface wind distribution and the main circulation of the sea indicates that the coupled model can reproduce the main characteristics of the Mediterranean Sea surface and intermediate layer circulation as well as the seasonal variability of wind speed and direction when it is compared with the available observational datasets. The results also reveal that the simulated near-surface wind speed and direction have poor performance in the Gulf of Lion and surrounding regions that also affects the large positive SST bias in the region due to the insufficient horizontal resolution of the atmospheric component of the coupled modeling system. The simulated seasonal climatologies of the surface heat flux components are also consistent with the CORE.2 and NOCS datasets along with the overestimation in net long-wave radiation and latent heat flux (or evaporation, E), although a large observational uncertainty is found in these variables. Also, the coupled model tends to improve the latent heat flux by providing a better representation of the air-sea interaction as well as total heat flux budget over the sea. Both models are also able to reproduce the temporal evolution of

  13. The lightning activity associated with the dry and moist convections in the Himalayan Regions

    NASA Astrophysics Data System (ADS)

    Penki, R. K.; Kamra, A. K.

    2013-06-01

    Lightning activity in the dry environment of northwest India and Pakistan (NW) and in the moist environment of northeast India (NE) has been examined from the Optical Transient Detector and Lightning Imaging Sensor data obtained from the Tropical Rainfall Measuring Mission satellite during 1995-2010. In the NW region, seasonal variation of flash rate is annual with a maximum in July but is semi-annual with a primary maximum in April and a secondary maximum in September, in the NE region. On diurnal scale, flash rate is the maximum in the afternoons, in both the NE and NW regions. The correlation of flash rate with convective parameters, viz. surface temperature, convective available potential energy (CAPE) and outgoing long-wave radiation is better with convective activity in the NW than in the NE region. Mean value of aerosol optical depth at 550 nm is ~ 26% higher and is highly correlated with flash rate in NW as compared to that in NE. Results indicate that CAPE is ~ 120 times more efficient in NW than in the NE region for production of lightning. The empirical orthogonal function analysis of flash rate, surface temperature, and CAPE shows that variance of lightning activity in these regions cannot be fully explained by the variance in the surface temperature and CAPE alone, and that some other factors, such as orographic lifting, precipitation, topography, etc., may also contribute to this variance in these mountainous regions. Further, the increase in CAPE due to orographic lifting in the Himalayan foothills in the NE region may contribute to ~ 7.5% increase in lightning activity. Relative roles of the thermally induced and moisture-induced changes in CAPE are examined in these regions. This study merely raises the questions, and that additional research is required for explaining the fundamental reasons for the reported observations here.

  14. Regional distribution pattern of groundwater heavy metals resulting from agricultural activities

    NASA Astrophysics Data System (ADS)

    Nouri, J.; Mahvi, A. H.; Jahed, G. R.; Babaei, A. A.

    2008-09-01

    Contaminations of groundwater by heavy metals due to agricultural activities are growing recently. The objective of this study was to evaluate and map regional patterns of heavy metals (Cd, Zn and Cu) in groundwater on a plain with high agricultural activities. The study was conducted to investigate the concentration of heavy metals and distribution in groundwater in regions of Shush Danial and Andimeshk aquifers in the southern part of Iran. Presently, groundwater is the only appropriate and widely used source of drinking water for rural and urban communities in this region. The region covers an area of 1,100 km2 between the Dez and Karkhe rivers, which lead to the Persian Gulf. For this study, the region was divided into four sub-regions A, B, C and D. Additionally, 168 groundwater samples were collected from 42 water wells during the earlier months of 2004. The flame atomic absorption spectrometry (AAS-Flame) was used to measure the concentration of heavy metals in water samples and the Surfer software was used for determination of the contour map of metal distribution. The results demonstrated that in all of the samples, Cd and Zn concentrations were below the EPA MCLG and EPA secondary standard, respectively. However, the Cu contents of 4.8 % of all samples were higher than EPA MCL. It is also indicated that the concentrations of metals were more pronounced at the southern part of the studied region than at the others. The analysis of fertilizers applied for agricultural activities at this region also indicated that a great majority of the above-mentioned heavy metals were discharged into the environment. Absence of confining layers, proximity to land surface, excess agricultural activities in the southern part and groundwater flow direction that is generally from the north to the southern parts in this area make the southern region of the Shush plain especially vulnerable to pollution by heavy metals than by other contaminants.

  15. Determining heating timescales in solar active region cores from AIA/SDO Fe XVIII images

    SciTech Connect

    Ugarte-Urra, Ignacio; Warren, Harry P.

    2014-03-01

    We present a study of the frequency of transient brightenings in the core of solar active regions as observed in the Fe XVIII line component of AIA/SDO 94 Å filter images. The Fe XVIII emission is isolated using an empirical correction to remove the contribution of 'warm' emission to this channel. Comparing with simultaneous observations from EIS/Hinode, we find that the variability observed in Fe XVIII is strongly correlated with the emission from lines formed at similar temperatures. We examine the evolution of loops in the cores of active regions at various stages of evolution. Using a newly developed event detection algorithm, we characterize the distribution of event frequency, duration, and magnitude in these active regions. These distributions are similar for regions of similar age and show a consistent pattern as the regions age. This suggests that these characteristics are important constraints for models of solar active regions. We find that the typical frequency of the intensity fluctuations is about 1400 s for any given line of sight, i.e., about two to three events per hour. Using the EBTEL 0D hydrodynamic model, however, we show that this only sets a lower limit on the heating frequency along that line of sight.

  16. Differential age-related changes in mitochondrial DNA repair activities in mouse brain regions

    PubMed Central

    Gredilla, Ricardo; Garm, Christian; Holm, Rikke; Bohr, Vilhelm A.; Stevnsner, Tinna

    2008-01-01

    Aging in the brain is characterized by increased susceptibility to neuronal loss and functional decline, and mitochondrial DNA (mtDNA) mutations are thought to play an important role in these processes. Due to the proximity of mtDNA to the main sites of mitochondrial free radical generation, oxidative stress is a major source of DNA mutations in mitochondria. The base excision repair (BER) pathway removes oxidative lesions from mtDNA, thereby constituting an important mechanism to avoid accumulation of mtDNA mutations. The complexity of the brain implies that exposure and defence against oxidative stress varies among brain regions and hence some regions may be particularly prone to accumulation of mtDNA damages. In the current study we investigated the efficiency of the BER pathway throughout the murine lifespan in mitochondria from cortex and hippocampus, regions that are central in mammalian cognition, and which are severely affected during aging and in neurodegenerative diseases. A regional specific regulation of mitochondrial DNA repair activities was observed with aging. In cortical mitochondria, DNA glycosylase activities peaked at middle-age followed by a significant drop at old age. However, only minor changes were observed in hippocampal mitochondria during the whole lifespan of the animals. Furthermore, DNA glycosylase activities were lower in hippocampal than in cortical mitochondria. Mitochondrial AP endonuclease activity increased in old animals in both brain regions. Our data suggest an important regional specific regulation of mitochondrial BER during aging. PMID:18701195

  17. Web-based assessments of physical activity in youth: considerations for design and scale calibration.

    PubMed

    Saint-Maurice, Pedro F; Welk, Gregory J

    2014-01-01

    This paper describes the design and methods involved in calibrating a Web-based self-report instrument to estimate physical activity behavior. The limitations of self-report measures are well known, but calibration methods enable the reported information to be equated to estimates obtained from objective data. This paper summarizes design considerations for effective development and calibration of physical activity self-report measures. Each of the design considerations is put into context and followed by a practical application based on our ongoing calibration research with a promising online self-report tool called the Youth Activity Profile (YAP). We first describe the overall concept of calibration and how this influences the selection of appropriate self-report tools for this population. We point out the advantages and disadvantages of different monitoring devices since the choice of the criterion measure and the strategies used to minimize error in the measure can dramatically improve the quality of the data. We summarize strategies to ensure quality control in data collection and discuss analytical considerations involved in group- vs individual-level inference. For cross-validation procedures, we describe the advantages of equivalence testing procedures that directly test and quantify agreement. Lastly, we introduce the unique challenges encountered when transitioning from paper to a Web-based tool. The Web offers considerable potential for broad adoption but an iterative calibration approach focused on continued refinement is needed to ensure that estimates are generalizable across individuals, regions, seasons and countries. PMID:25448192

  18. Web-Based Assessments of Physical Activity in Youth: Considerations for Design and Scale Calibration

    PubMed Central

    2014-01-01

    This paper describes the design and methods involved in calibrating a Web-based self-report instrument to estimate physical activity behavior. The limitations of self-report measures are well known, but calibration methods enable the reported information to be equated to estimates obtained from objective data. This paper summarizes design considerations for effective development and calibration of physical activity self-report measures. Each of the design considerations is put into context and followed by a practical application based on our ongoing calibration research with a promising online self-report tool called the Youth Activity Profile (YAP). We first describe the overall concept of calibration and how this influences the selection of appropriate self-report tools for this population. We point out the advantages and disadvantages of different monitoring devices since the choice of the criterion measure and the strategies used to minimize error in the measure can dramatically improve the quality of the data. We summarize strategies to ensure quality control in data collection and discuss analytical considerations involved in group- vs individual-level inference. For cross-validation procedures, we describe the advantages of equivalence testing procedures that directly test and quantify agreement. Lastly, we introduce the unique challenges encountered when transitioning from paper to a Web-based tool. The Web offers considerable potential for broad adoption but an iterative calibration approach focused on continued refinement is needed to ensure that estimates are generalizable across individuals, regions, seasons and countries. PMID:25448192

  19. Web-based assessments of physical activity in youth: considerations for design and scale calibration.

    PubMed

    Saint-Maurice, Pedro F; Welk, Gregory J

    2014-01-01

    This paper describes the design and methods involved in calibrating a Web-based self-report instrument to estimate physical activity behavior. The limitations of self-report measures are well known, but calibration methods enable the reported information to be equated to estimates obtained from objective data. This paper summarizes design considerations for effective development and calibration of physical activity self-report measures. Each of the design considerations is put into context and followed by a practical application based on our ongoing calibration research with a promising online self-report tool called the Youth Activity Profile (YAP). We first describe the overall concept of calibration and how this influences the selection of appropriate self-report tools for this population. We point out the advantages and disadvantages of different monitoring devices since the choice of the criterion measure and the strategies used to minimize error in the measure can dramatically improve the quality of the data. We summarize strategies to ensure quality control in data collection and discuss analytical considerations involved in group- vs individual-level inference. For cross-validation procedures, we describe the advantages of equivalence testing procedures that directly test and quantify agreement. Lastly, we introduce the unique challenges encountered when transitioning from paper to a Web-based tool. The Web offers considerable potential for broad adoption but an iterative calibration approach focused on continued refinement is needed to ensure that estimates are generalizable across individuals, regions, seasons and countries.

  20. Designation of less favorable areas by the regionalization of soil degradation on various spatial scales

    NASA Astrophysics Data System (ADS)

    Pásztor, L.; Szabó, J.; Bakacsi, Zs.; Laborczi, A.

    2009-04-01

    One of the main objectives of the EU's Common Agricultural Policy is to encourage maintaining agricultural production in less favorable areas (LFA) in order (among others) to sustain agricultural production and use natural resources, in such a way to secure both stable production and income to farmers and to protect the environment. LFA assignment has both ecological and severe economical aspects. Delimitation of LFAs can be carried out by using biophysical diagnostic criteria on low soil productivity and poor climate conditions. Identification of low-productivity areas requires regionalization of soil functions related to food and other biomass production. This process can be carried out in different scales from national to local level, but always requires map-based pedological and further environmental information with appropriate spatial resolution. For the regionalization of less productive areas in national scale a functional approach was used which integrates the knowledge on soil degradation processes in nationwide level. Specific soil threats were classified into ranked categories. Supposing (quasi)uniform distribution of vulnerability measure along these classes, we introduced a "standardized" value as a ratio of the class order to the maximum class order expressed in percentage. For the overall spatial characterization of degradation status, spatial information was integrated in a result map by summarizing the degradation specific "standardized" cell values. This map in one hand has been used for the delineation of soil degradation regions. On the other hand appropriate spatial aggregation of index values on geographical and administrative regions is suitable for their quantitative comparison thus they can be ranked and this feature can be used for the identification of less favorable areas. At the more detailed, county level the Digital Kreybig Soil Information System was used as a tool of the regionalization of soil functions related to soil

  1. Design and Usability Evaluation of Social Mobile Diabetes Management System in the Gulf Region

    PubMed Central

    2016-01-01

    Background The prevalence of diabetes in the Gulf States is one of the highest globally. It is estimated that 20% of the population in the region has been diagnosed with diabetes and according to the International Diabetes Federation (IDF), five of the IDF’s “top 10” countries for diabetes prevalence in 2011 and projected for 2030 are in this region. In recent years, there have been an increasing number of clinical studies advocating the use of mobile phone technology for diabetes self-management with improved clinical outcomes. However, there are few studies to date addressing the application of mobile diabetes management in the Gulf region, particularly in the Kingdom of Saudi Arabia (KSA), where there is exponential increase in mobile phone usage and access to social networking. Objective The objective of this paper is to present the design and development of a new mobile health system for social behavioral change and management tailored for Saudi patients with diabetes called Saudi Arabia Networking for Aiding Diabetes (SANAD). A usability study for the SANAD system is presented to validate the acceptability of using mobile technologies among patients with diabetes in the KSA and the Gulf region. Methods The SANAD system was developed using mobile phone technology with diabetes management and social networking modules. For the usability study the Questionnaire for User Interaction Satisfaction was used to evaluate the usability aspect of the SANAD system. A total of 33 users with type 2 diabetes participated in the study. Results The key modules of the SANAD system consist of (1) a mobile diabetes management module; (2) a social networking module; and (3) a cognitive behavioral therapy module for behavioral change issues. The preliminary results of the usability study indicated general acceptance of the patients in using the system with higher usability rating in patients with type 2 diabetes. Conclusions We found that the acceptability of the system was

  2. Design and comparative anticonvulsant activity assessment of CNS-active alkyl-carbamoyl imidazole derivatives.

    PubMed

    Mawasi, Hafiz; Bibi, David; Bialer, Meir

    2016-09-15

    A novel series of carbamoyl derivatives of alkylimidazole has been designed and their anticonvulsant activity was comparatively evaluated in the mice- and rats-maximal-electroshock (MES), subcutaneous-metrazol (scMet) seizure tests and the mice-6Hz psychomotor (6Hz) models. The ten new designed molecules contain in their chemical structure imidazole, alkyl side-chain and carbamate as three potential active moieties. In spite of the close structural features of the carbamoyl imidazole derivatives only compounds 7, 8, 13 and 16 were active at the MES test with ED50 values ranging from 12 to 20mg/kg coupled with high protective index (PI=TD50/ED50) values of 4.1-7.3 after ip administration to rats. A similar phenomenon was observed in mice where compounds 7, 8, 9, 12 had MES-ED50 values of 14-26mg/kg. Compounds 7 and 13 also demonstrated anticonvulsant activity in the 6Hz model with ED50 values of 32 and 44mg/kg, respectively. As the most active entities, compounds 7, 8 followed by 13 and 16, thus offer an optimal efficacy-safety profile and consequently, might be promising candidates for development as new antiepileptics. PMID:27469980

  3. Identification of furin pro-region determinants involved in folding and activation.

    PubMed Central

    Bissonnette, Lyne; Charest, Gabriel; Longpré, Jean-Michel; Lavigne, Pierre; Leduc, Richard

    2004-01-01

    The pro-region of the subtilisin-like convertase furin acts early in the biosynthetic pathway as an intramolecular chaperone to enable proper folding of the zymogen, and later on as an inhibitor to constrain the activity of the enzyme until it reaches the trans -Golgi network. To identify residues that are important for pro-region function, we initially identified amino acids that are conserved among the pro-regions of various mammalian convertases. Site-directed mutagenesis of 17 selected amino acids within the 89-residue pro-region and biosynthetic labelling revealed that I60A-furin and H66A-furin were rapidly degraded in a proteasome-dependent manner, while W34A-furin and F67A-furin did not show any autocatalytic activation. Intriguingly, the latter mutants proteolytically cleaved pro-von Willebrand factor precursor to the mature polypeptide, suggesting that the mutations permitted proper folding, but did not allow the pro-region to exercise its role in inhibiting the enzyme. Homology modelling of furin's pro-region revealed that residues Ile-60 and His-66 might be crucial in forming the binding interface with the catalytic domain, while residues Trp-34 and Phe-67 might be involved in maintaining a hydrophobic core within the pro-region itself. These results provide structural insights into the dual role of furin's pro-region. PMID:14741044

  4. Variegation of comet 67P/Churyumov-Gerasimenko in regions showing activity

    NASA Astrophysics Data System (ADS)

    Oklay, N.; Vincent, J.-B.; Fornasier, S.; Pajola, M.; Besse, S.; Davidsson, B. J. R.; Lara, L. M.; Mottola, S.; Naletto, G.; Sierks, H.; Barucci, A. M.; Scholten, F.; Preusker, F.; Pommerol, A.; Masoumzadeh, N.; Lazzarin, M.; Barbieri, C.; Lamy, P. L.; Rodrigo, R.; Koschny, D.; Rickman, H.; A'Hearn, M. F.; Bertaux, J.-L.; Bertini, I.; Bodewits, D.; Cremonese, G.; Da Deppo, V.; Debei, S.; De Cecco, M.; Fulle, M.; Groussin, O.; Gutiérrez, P. J.; Güttler, C.; Hall, I.; Hofmann, M.; Hviid, S. F.; Ip, W.-H.; Jorda, L.; Keller, H. U.; Knollenberg, J.; Kovacs, G.; Kramm, J.-R.; Kührt, E.; Küppers, M.; Lin, Z.-Y.; Lopez Moreno, J. J.; Marzari, F.; Moreno, F.; Shi, X.; Thomas, N.; Toth, I.; Tubiana, C.

    2016-02-01

    Aims.We carried out an investigation of the surface variegation of comet 67P/Churyumov-Gerasimenko, the detection of regions showing activity, the determination of active and inactive surface regions of the comet with spectral methods, and the detection of fallback material. Methods: We analyzed multispectral data generated with Optical, Spectroscopic, and Infrared Remote Imaging System (OSIRIS) narrow angle camera (NAC) observations via spectral techniques, reflectance ratios, and spectral slopes in order to study active regions. We applied clustering analysis to the results of the reflectance ratios, and introduced the new technique of activity thresholds to detect areas potentially enriched in volatiles. Results: Local color inhomogeneities are detected over the investigated surface regions. Active regions, such as Hapi, the active pits of Seth and Ma'at, the clustered and isolated bright features in Imhotep, the alcoves in Seth and Ma'at, and the large alcove in Anuket, have bluer spectra than the overall surface. The spectra generated with OSIRIS NAC observations are dominated by cometary emissions of around 700 nm to 750 nm as a result of the coma between the comet's surface and the camera. One of the two isolated bright features in the Imhotep region displays an absorption band of around 700 nm, which probably indicates the existence of hydrated silicates. An absorption band with a center between 800-900 nm is tentatively observed in some regions of the nucleus surface. This absorption band can be explained by the crystal field absorption of Fe2+, which is a common spectral feature seen in silicates.

  5. Minifilament Eruptions that Drive Coronal Jets in a Solar Active Region

    NASA Astrophysics Data System (ADS)

    Sterling, Alphonse C.; Moore, Ronald L.; Falconer, David; Panesar, Navdeep; Akiyama, Sachiko; Yashiro, Seiji; Gopalswamy, Nat

    2016-05-01

    Solar coronal jets are common in both coronal holes and in active regions. Recently, Sterling et al. (2015), using data from Hinode/XRT and SDO/AIA, found that coronal jets originating in polar coronal holes result from the eruption of small-scale filaments (minifilaments). The jet bright point (JBP) seen in X-rays and hotter EUV channels off to one side of the base of the jet's spire develops at the location where the minifilament erupts, consistent with the JBPs being miniature versions of typical solar flares that occur in the wake of large-scale filament eruptions. Here we consider whether active region coronal jets also result from the same minifilament-eruption mechanism, or whether they instead result from a different mechanism, such as the hitherto popular ``emerging flux'' model for jets. We present observations of an on-disk active region that produced numerous jets on 2012 June 30, using data from SDO/AIA and HMI, and from GOES/SXI. We find that several of these active region jets also originate with eruptions of miniature filaments (size scale ~20'') emanating from small-scale magnetic neutral lines of the region. This demonstrates that active region coronal jets are indeed frequently driven by minifilament eruptions. Other jets from the active region were also consistent with their drivers being minifilament eruptions, but we could not confirm this because the onsets of those jets were hidden from our view. This work was supported by funding from NASA/LWS, NASA/HGI, and Hinode.

  6. An Introduction to the Importance of Photography and Gaming Simulation to the Regional Planning Process, Environmental Design and Community Development.

    ERIC Educational Resources Information Center

    Steward, W. C.; Menary, John A.

    This report attempts to interrelate essential concepts in visual communication and gaming-simulation with problem solving and education in the fields of regional environmental planning, design, and community development. Use of these methodologies in educating the general public in regional planning topics is also covered. The use of visual or…

  7. Different Modes of Turbulence in the Active Regions of the Solar Photosphere

    NASA Astrophysics Data System (ADS)

    Kozak, L. V.; Kostik, R. I.; Cheremnykh, O. K.

    In work the range of different methods for the analysis of characteristics of turbulent processes in the active regions of the solar photosphere has been used. The changes of fluctuations distribution function and its moments were analyzed, spectral analysis was carried out.It was found out from the observations of active region carried out with the 70-cm vacuum tower telescope VTT in Isanie (Tenerife Island, Spain) that the turbulent processes in the sun photosphere are characterized by two different spectra of turbulence. The first one of them is well known Kolmohorov spectrum, which describes the plasma with zero mean magnetic field. The second one is the Kraichnan spectrum with a different from zero mean magnetic field. Transition from one spectrum type to another one occurs at scale of 3 Mm.We have to note that the scale 3 Mm corresponds to one of mesogranulation and testifies about non-zero mean magnetic fields for the consideration of regions exceeding the granulation in active regions of the photosphere. Besides, this clears the possibility of appearance of selforganizing magnetic plasma structures such as spots, active regions and complexes of activity.

  8. Spontaneous regional brain activity links restrained eating to later weight gain among young women.

    PubMed

    Dong, Debo; Jackson, Todd; Wang, Yulin; Chen, Hong

    2015-07-01

    Theory and prospective studies have linked restrained eating (RE) to risk for future weight gain and the onset of obesity, but little is known about resting state neural activity that may underlie this association. To address this gap, resting fMRI was used to test the extent to which spontaneous neural activity in regions associated with inhibitory control and food reward account for potential relations between baseline RE levels and changes in body weight among dieters over a one-year interval. Spontaneous regional activity patterns corresponding to RE were assessed among 50 young women using regional homogeneity (ReHo) analysis, which measured temporal synchronization of spontaneous fluctuations within a food deprivation condition. Analyses indicated higher baseline RE scores predicted more weight gain at a one-year follow-up. Furthermore, food-deprived dieting women with high dietary restraint scores exhibited more spontaneous local activity in brain regions associated with the expectation and valuation for food reward [i.e., orbitofrontal cortex (OFC)/ventromedial prefrontal cortex (VMPFC)] and reduced spontaneous local activity in inhibitory control regions [i.e., bilateral dorsal-lateral prefrontal cortex (DLPFC)] at baseline. Notably, the association between baseline RE and follow-up weight gain was mediated by decreased local synchronization of the right DLPFC in particular and, to a lesser degree, increased local synchronization of the right VMPFC. In conjunction with previous research, these findings highlight possible neural mechanisms underlying the relation between RE and risk for weight gain. PMID:26004091

  9. Spontaneous regional brain activity links restrained eating to later weight gain among young women.

    PubMed

    Dong, Debo; Jackson, Todd; Wang, Yulin; Chen, Hong

    2015-07-01

    Theory and prospective studies have linked restrained eating (RE) to risk for future weight gain and the onset of obesity, but little is known about resting state neural activity that may underlie this association. To address this gap, resting fMRI was used to test the extent to which spontaneous neural activity in regions associated with inhibitory control and food reward account for potential relations between baseline RE levels and changes in body weight among dieters over a one-year interval. Spontaneous regional activity patterns corresponding to RE were assessed among 50 young women using regional homogeneity (ReHo) analysis, which measured temporal synchronization of spontaneous fluctuations within a food deprivation condition. Analyses indicated higher baseline RE scores predicted more weight gain at a one-year follow-up. Furthermore, food-deprived dieting women with high dietary restraint scores exhibited more spontaneous local activity in brain regions associated with the expectation and valuation for food reward [i.e., orbitofrontal cortex (OFC)/ventromedial prefrontal cortex (VMPFC)] and reduced spontaneous local activity in inhibitory control regions [i.e., bilateral dorsal-lateral prefrontal cortex (DLPFC)] at baseline. Notably, the association between baseline RE and follow-up weight gain was mediated by decreased local synchronization of the right DLPFC in particular and, to a lesser degree, increased local synchronization of the right VMPFC. In conjunction with previous research, these findings highlight possible neural mechanisms underlying the relation between RE and risk for weight gain.

  10. The study of a spatial relationship between the Equatorial coronal hole and the Active region

    NASA Astrophysics Data System (ADS)

    Karna, Mahendra; Karna, Nishu

    2016-05-01

    The 11-year solar cycle is characterized by the periodic change in the solar activity like sunspot numbers, coronal holes, active regions, eruptions such as flares and coronal mass ejections. We study the relationship between equatorial coronal holes (ECH) and the active regions (AR) as coronal hole positions and sizes change with the solar cycle. We made a detailed study for two solar maximum: Solar Cycle 23 (1999, 2000, 2001 and 2002) and Solar Cycle 24 (2011, 2012 and 2013). We used publically available Heliophysics Feature Catalogue and NOAA Solar Geophysical data for. Moreover, we used daily Solar Region Summary (SRS) data from SWPC/NOAA website. We examined the position of ECH and AR and noted that during a maximum of 23, the majority of ECH were not near active regions. However, in cycle 24 coronal holes and equatorial holes were more close to each other. Moreover, we noticed the asymmetry in AR migrations towards the lower latitude in both Northern and Southern hemisphere in cycle 23. While, no such notable asymmetrical behavior was observed in a maximum of cycle 24. Our goal is to extend the study with cycle 21 and 22 and examine the correlation between equatorial holes, the active regions, and the flares. This combined study will shed light in determining the distribution of flares.

  11. First steps towards the development of regional magnetic indices designed for South America

    NASA Astrophysics Data System (ADS)

    Denardini, Clezio Marcos; Moro, Juliano; Araujo Resende, Laysa Cristina; Chen, Sony Su

    In the present paper we present the first steps towards the development of regional magnetic indices designed for South America, based on data collected by the EMBRACE Magnetometer Network, which so far is planned to cover most of the Easter Southern American longitudinal sector. Thereafter, we provide details of the development of the region K, named Ksa (K South America), and of the proxy for the Dst Index, obtained in near real-time (1 minute cadence with 5 minutes latency). We also compare the evolution of our indices with the evolution of the Kp and Dst index during geomagnetic storms occurred in 2012 and 2013. We will show some similarities representing the accuracy of our measurements and some dissimilarity that may be attributed the presence of the South American Magnetic Anomaly (SAMA). This, in turn, may reflect in the global models that use such indices for disturbance time estimates during different solar cycles. Contacting Author: C. M. Denardini (clezio.denardin@inpe.br)

  12. Multirate Flutter Suppression System Design for the Benchmark Active Controls Technology Wing. Part 1; Theory and Design Procedure

    NASA Technical Reports Server (NTRS)

    Mason, Gregory S.; Berg, Martin C.; Mukhopadhyay, Vivek

    2002-01-01

    To study the effectiveness of various control system design methodologies, the NASA Langley Research Center initiated the Benchmark Active Controls Project. In this project, the various methodologies were applied to design a flutter suppression system for the Benchmark Active Controls Technology (BACT) Wing. This report describes a project at the University of Washington to design a multirate suppression system for the BACT wing. The objective of the project was two fold. First, to develop a methodology for designing robust multirate compensators, and second, to demonstrate the methodology by applying it to the design of a multirate flutter suppression system for the BACT wing.

  13. Optimal design of active and semi-active suspensions including time delays and preview

    NASA Astrophysics Data System (ADS)

    Hac', A.; Youn, I.

    1993-10-01

    Several control laws for active and semi-active suspension based on a linear half car model are derived and investigated. The strategies proposed take full advantage of the fact that the road input to the rear wheels is a delayed version of that to the front wheels, which in turn can be obtained either from the measurements of the front wheels and body motions or by direct preview of road irregularities if preview sensors are available. The suspension systems are optimized with respect to ride comfort, road holding and suspension rattle space as expressed by the mean-square-values of body acceleration (including effects of heave and pitch), tire deflections and front and rear suspension travels. The optimal control laws that minimize the given performance index and include passivity constraints in the semi-active case are derived using calculus of variation. The optimal semi-active suspension becomes piecewise linear, varying between passive and fully active systems and combinations of them. The performances of active and semi-active systems with and without preview were evaluated by numerical simulation in the time and frequency domains. The results show that incorporation of time delay between the front and rear axles in controller design improves the dynamic behavior of the rear axle and control of body pitch motion, while additional preview improves front wheel dynamics and body heave.

  14. Mechanism of formation of a dipole magnetic field in the central regions of active galaxies

    NASA Astrophysics Data System (ADS)

    Andreasyan, R. R.

    1996-01-01

    A model of the formation of large-scale magnetic fields of dipole configuration in the central regions (r ≈ 100 pc) of active galaxies is studied. It is assumed that these regions contain a rapidly rotating, highly ionized gas (Ω ≈ 5·10-15 sec, Ne ≈ 103 cm-3). Ionized matter escapes from the center of the region with a velocity of several hundred km/sec and is entrained by the rotation of the surrounding medium. Biermann's "battery" effect [L. Biermann, Z. Naturforsch., 5a, 65 (1950)] operates under such conditions, and circular electric currents are formed in the medium, which amplify the dipole magnetic fields. During the active phase of a galaxy, about 108 years, the magnetic field strength at the boundary of this region may reach 10-4 10-3 G.

  15. Designing slanted soil system for greywater treatment for irrigation purposes in rural area of arid regions.

    PubMed

    Maiga, Y; Moyenga, D; Nikiema, B C; Ushijima, K; Maiga, A H; Funamizu, N

    2014-01-01

    To solve the unpleasant disposal of greywater in rural area and allow its collection for reuse in gardening, a slanted soil treatment system (SSTS) was designed and installed in two households. Granitic gravel of 1-9 mm size was used as the filter medium. The aim of this study was to design a SSTS and assess its suitability as a treatment system allowing greywater reuse in gardening. The efficiency of the SSTS was assessed based on organic matter and bacterial pollution removal. The developed SSTS allowed the collection of greywater from three main sources (shower, dishwashing and laundry) in rural area. The SSTS is efficient in removing at least 50% of suspended solids, chemical oxygen demand and biological oxygen demand. The study highlighted that, contrary to the common perception, greywater streams in rural area are heavily polluted with faecal indicators. The removal efficiency of faecal indicators was lower than 2 log units, and the bacteriological quality of the effluents is generally higher than the WHO reuse guidelines for restricted irrigation. Longer retention time is required to increase the efficiency. The possibility of reusing the treated greywater as irrigation water is discussed on the basis of various qualitative parameters. The SSTS is a promising greywater treatment system for small communities in the rural area in the Sahelian region. To increase the treatment efficiency, future research will focus on the characteristics of the SSTS, the grain size and the establishment of a pretreatment step.

  16. Temperature structure of active regions deduced from helium-like sulphur lines

    NASA Technical Reports Server (NTRS)

    Watanabe, Tetsuya; Hara, Hirohisa; Shimizu, Toshifumi; Hiei, Eijiro; Bentley, Robert D.; Lang, James; Phillips, Kenneth J. H.; Pike, C. David; Fludra, Andrzej; Bromage, Barbara J. I.

    1995-01-01

    Solar active-region temperatures have been determined from the full-Sun spectra of helium-like sulfur (S XV) observed by the Bragg Crystal Spectrometer on Board the Yohkoh satellite. The average temperature deduced from S XV is demonstrated to vary with the solar activity level: A temperature of 2.5 x 10(exp 6) K is derived from the spectra taken during low solar activity, similar to the general corona, while 4 x 10(exp 6) K is obtained during a higher activity phase. For the latter, the high- temperature tail of the differential emission measure of active regions is found most likely due to the superposition of numerous flare-like events (micro/nano-flares).

  17. Seasonal forecasting of lightning and thunderstorm activity in tropical and temperate regions of the world.

    PubMed

    Dowdy, Andrew J

    2016-01-01

    Thunderstorms are convective systems characterised by the occurrence of lightning. Lightning and thunderstorm activity has been increasingly studied in recent years in relation to the El Niño/Southern Oscillation (ENSO) and various other large-scale modes of atmospheric and oceanic variability. Large-scale modes of variability can sometimes be predictable several months in advance, suggesting potential for seasonal forecasting of lightning and thunderstorm activity in various regions throughout the world. To investigate this possibility, seasonal lightning activity in the world's tropical and temperate regions is examined here in relation to numerous different large-scale modes of variability. Of the seven modes of variability examined, ENSO has the strongest relationship with lightning activity during each individual season, with relatively little relationship for the other modes of variability. A measure of ENSO variability (the NINO3.4 index) is significantly correlated to local lightning activity at 53% of locations for one or more seasons throughout the year. Variations in atmospheric parameters commonly associated with thunderstorm activity are found to provide a plausible physical explanation for the variations in lightning activity associated with ENSO. It is demonstrated that there is potential for accurately predicting lightning and thunderstorm activity several months in advance in various regions throughout the world. PMID:26865431

  18. Seasonal forecasting of lightning and thunderstorm activity in tropical and temperate regions of the world

    PubMed Central

    Dowdy, Andrew J.

    2016-01-01

    Thunderstorms are convective systems characterised by the occurrence of lightning. Lightning and thunderstorm activity has been increasingly studied in recent years in relation to the El Niño/Southern Oscillation (ENSO) and various other large-scale modes of atmospheric and oceanic variability. Large-scale modes of variability can sometimes be predictable several months in advance, suggesting potential for seasonal forecasting of lightning and thunderstorm activity in various regions throughout the world. To investigate this possibility, seasonal lightning activity in the world’s tropical and temperate regions is examined here in relation to numerous different large-scale modes of variability. Of the seven modes of variability examined, ENSO has the strongest relationship with lightning activity during each individual season, with relatively little relationship for the other modes of variability. A measure of ENSO variability (the NINO3.4 index) is significantly correlated to local lightning activity at 53% of locations for one or more seasons throughout the year. Variations in atmospheric parameters commonly associated with thunderstorm activity are found to provide a plausible physical explanation for the variations in lightning activity associated with ENSO. It is demonstrated that there is potential for accurately predicting lightning and thunderstorm activity several months in advance in various regions throughout the world. PMID:26865431

  19. Seasonal forecasting of lightning and thunderstorm activity in tropical and temperate regions of the world.

    PubMed

    Dowdy, Andrew J

    2016-02-11

    Thunderstorms are convective systems characterised by the occurrence of lightning. Lightning and thunderstorm activity has been increasingly studied in recent years in relation to the El Niño/Southern Oscillation (ENSO) and various other large-scale modes of atmospheric and oceanic variability. Large-scale modes of variability can sometimes be predictable several months in advance, suggesting potential for seasonal forecasting of lightning and thunderstorm activity in various regions throughout the world. To investigate this possibility, seasonal lightning activity in the world's tropical and temperate regions is examined here in relation to numerous different large-scale modes of variability. Of the seven modes of variability examined, ENSO has the strongest relationship with lightning activity during each individual season, with relatively little relationship for the other modes of variability. A measure of ENSO variability (the NINO3.4 index) is significantly correlated to local lightning activity at 53% of locations for one or more seasons throughout the year. Variations in atmospheric parameters commonly associated with thunderstorm activity are found to provide a plausible physical explanation for the variations in lightning activity associated with ENSO. It is demonstrated that there is potential for accurately predicting lightning and thunderstorm activity several months in advance in various regions throughout the world.

  20. Plasma outflows at the border of active regions and the solar wind

    NASA Astrophysics Data System (ADS)

    Nuevo, F. A.; Mandrini, C. H.; Vásquez, A. M.; Deumoulin, P.; Van Driel-Gesztely, L.; Baker, D.; Cristiani, G. D.; Pick, M.; Culhane, J. L.

    We present a detailed topological analysis of active region (AR) 10978; based on a Potential Field Source Surface (PFSS) model. AR 10978 is a standard bipolar region which appears fully covered by the magnetic field lines of a coronal streamer. Despite this simple magnetic configuration; our analysis shows that it is possible for the AR plasma; contained in the outflows observed at the AR borders; to be released into the solar wind via magnetic reconnection.

  1. Using Magnetic Helicity Diagnostics to Determine the Nature of Solar Active-Region Formation

    NASA Astrophysics Data System (ADS)

    Georgoulis, Manolis K.

    Employing a novel nonlinear force-free (NLFF) method that self-consistently infers instantaneous free magnetic-energy and relative magnetic-helicity budgets from single photospheric vector magnetograms, we recently constructed the magnetic energy-helicity (EH) diagram of solar active regions. The EH diagram implies dominant relative helicities of left-handed or right-handed chiralities for the great majority of active regions. The amplitude (budget) of these helicities scales monotonically with the free magnetic energy. This constructive, strongly preferential accumulation of a certain sense of magnetic helicity seems to disqualify recently proposed mechanisms relying on a largely random near-surface convection for the formation of the great majority of active regions. The existing qualitative formation mechanism for these regions remains the conventional Omega-loop emergence following a buoyant ascension from the bottom of the convection zone. However, exceptions to this rule include even eruptive active regions: NOAA AR 11283 is an obvious outlier to the EH diagram, involving significant free magnetic energy with a small relative magnetic helicity. Relying on a timeseries of vector magnetograms of this region, our methodology shows nearly canceling amounts of both senses of helicity and an overall course from a weakly left-handed to a weakly right-handed structure, in the course of which a major eruption occurs. For this and similarly behaving active regions the latest near-surface formation scenario might conceivably be employed successfully. Research partially supported by the EU Seventh Framework Programme under grant agreement No. PIRG07-GA-2010-268245 and by the European Union Social Fund (ESF) and Greek national funds through the Operational Program "Education and Lifelong Learning" of the National Strategic Reference Framework (NSRF) - Research Funding Program: Thales. Investing in knowledge society through the European Social Fund.

  2. UVCS Observations of Slow Plasma Flow in the Corona Above Active Regions

    NASA Astrophysics Data System (ADS)

    Woo, R.; Habbal, S. R.

    2005-05-01

    The elusive source of slow solar wind has been the subject of ongoing discussion and debate. Observations of solar wind speed near the Earth orbit, first with IPS (interplanetary scintillation) and later with Ulysses in situ measurements, have suggested that some slow solar wind may be associated with active regions (Kojima & Kakinuma 1987; Woo, Habbal & Feldman 2004). The ability of SOHO UVCS Doppler dimming measurements to provide estimates of solar wind speed in the corona (Kohl et al. 1995) has made it possible to investigate the distribution of flow near the Sun. In this paper, we will present results confirming that active regions are one of the sources of slow wind. Insight into the relationship between coronal streamers, active regions and plasma flow will also be discussed.

  3. Detailed correlation of type III radio bursts with H alpha activity. I - Active region of 22 May 1970.

    NASA Technical Reports Server (NTRS)

    Kuiper, T. B. H.; Pasachoff, J. M.

    1973-01-01

    Comparison of observations of type III impulsive radio bursts made at the Clark Lake Radio Observatory with high-spatial-resolution cinematographic observations taken at the Big Bear Solar Observatory. Use of the log-periodic radio interferometer makes it possible to localize the radio emission uniquely. This study concentrates on the particularly active region close to the limb on May 22, 1970. Sixteen of the 17 groups were associated with some H alpha activity, 11 of them with the start of such activity.

  4. Theta-Modulated Gamma-Band Synchronization Among Activated Regions During a Verb Generation Task

    PubMed Central

    Doesburg, Sam M.; Vinette, Sarah A.; Cheung, Michael J.; Pang, Elizabeth W.

    2012-01-01

    Expressive language is complex and involves processing within a distributed network of cortical regions. Functional MRI and magnetoencephalography (MEG) have identified brain areas critical for expressive language, but how these regions communicate across the network remains poorly understood. It is thought that synchronization of oscillations between neural populations, particularly at a gamma rate (>30 Hz), underlies functional integration within cortical networks. Modulation of gamma rhythms by theta-band oscillations (4–8 Hz) has been proposed as a mechanism for the integration of local cell coalitions into large-scale networks underlying cognition and perception. The present study tested the hypothesis that these oscillatory mechanisms of functional integration were present within the expressive language network. We recorded MEG while subjects performed a covert verb generation task. We localized activated cortical regions using beamformer analysis, calculated inter-regional phase locking between activated areas, and measured modulation of inter-regional gamma synchronization by theta phase. The results show task-dependent gamma-band synchronization among regions activated during the performance of the verb generation task, and we provide evidence that these transient and periodic instances of high-frequency connectivity were modulated by the phase of cortical theta oscillations. These findings suggest that oscillatory synchronization and cross-frequency interactions are mechanisms for functional integration among distributed brain areas supporting expressive language processing. PMID:22707946

  5. Signatures of Slow Solar Wind Streams from Active Regions in the Inner Corona

    NASA Astrophysics Data System (ADS)

    Slemzin, V.; Harra, L.; Urnov, A.; Kuzin, S.; Goryaev, F.; Berghmans, D.

    2013-08-01

    The identification of solar-wind sources is an important question in solar physics. The existing solar-wind models ( e.g., the Wang-Sheeley-Arge model) provide the approximate locations of the solar wind sources based on magnetic field extrapolations. It has been suggested recently that plasma outflows observed at the edges of active regions may be a source of the slow solar wind. To explore this we analyze an isolated active region (AR) adjacent to small coronal hole (CH) in July/August 2009. On 1 August, Hinode/EUV Imaging Spectrometer observations showed two compact outflow regions in the corona. Coronal rays were observed above the active-region coronal hole (ARCH) region on the eastern limb on 31 July by STEREO-A/EUVI and at the western limb on 7 August by CORONAS- Photon/TESIS telescopes. In both cases the coronal rays were co-aligned with open magnetic-field lines given by the potential field source surface model, which expanded into the streamer. The solar-wind parameters measured by STEREO-B, ACE, Wind, and STEREO-A confirmed the identification of the ARCH as a source region of the slow solar wind. The results of the study support the suggestion that coronal rays can represent signatures of outflows from ARs propagating in the inner corona along open field lines into the heliosphere.

  6. Determining the solar wind speed above active regions using remote radio-wave observations

    NASA Technical Reports Server (NTRS)

    Fainberg, J.; Stone, R. G.; Bougeret, J.-L.

    1983-01-01

    A new technique has made it possible to measure the velocity of portions of the solar wind during its flow outward from the sun. This analysis utilizes spacecraft (ISEE-3) observations of radio emission generated in regions of the solar wind associated with solar active regions. By tracking the source of these radio waves over periods of days, it is possible to measure the motion of the emission regions. Evidence of solar wind acceleration during this outward flow, consistent with theoretical models, has also been obtained.

  7. Materials for Consideration in Standardized Canister Design Activities.

    SciTech Connect

    Bryan, Charles R.; Ilgen, Anastasia Gennadyevna; Enos, David George; Teich-McGoldrick, Stephanie; Hardin, Ernest

    2014-10-01

    This document identifies materials and material mitigation processes that might be used in new designs for standardized canisters for storage, transportation, and disposal of spent nuclear fuel. It also addresses potential corrosion issues with existing dual-purpose canisters (DPCs) that could be addressed in new canister designs. The major potential corrosion risk during storage is stress corrosion cracking of the weld regions on the 304 SS/316 SS canister shell due to deliquescence of chloride salts on the surface. Two approaches are proposed to alleviate this potential risk. First, the existing canister materials (304 and 316 SS) could be used, but the welds mitigated to relieve residual stresses and/or sensitization. Alternatively, more corrosion-resistant steels such as super-austenitic or duplex stainless steels, could be used. Experimental testing is needed to verify that these alternatives would successfully reduce the risk of stress corrosion cracking during fuel storage. For disposal in a geologic repository, the canister will be enclosed in a corrosion-resistant or corrosion-allowance overpack that will provide barrier capability and mechanical strength. The canister shell will no longer have a barrier function and its containment integrity can be ignored. The basket and neutron absorbers within the canister have the important role of limiting the possibility of post-closure criticality. The time period for corrosion is much longer in the post-closure period, and one major unanswered question is whether the basket materials will corrode slowly enough to maintain structural integrity for at least 10,000 years. Whereas there is extensive literature on stainless steels, this evaluation recommends testing of 304 and 316 SS, and more corrosion-resistant steels such as super-austenitic, duplex, and super-duplex stainless steels, at repository-relevant physical and chemical conditions. Both general and localized corrosion testing methods would be used to

  8. ON THE STRENGTH OF THE HEMISPHERIC RULE AND THE ORIGIN OF ACTIVE-REGION HELICITY

    SciTech Connect

    Wang, Y.-M.

    2013-10-01

    Vector magnetograph and morphological observations have shown that the solar magnetic field tends to have negative (positive) helicity in the northern (southern) hemisphere, although only ∼60%-70% of active regions appear to obey this 'hemispheric rule'. In contrast, at least ∼80% of quiescent filaments and filament channels that form during the decay of active regions follow the rule. We attribute this discrepancy to the difficulty in determining the helicity sign of newly emerged active regions, which are dominated by their current-free component; as the transverse field is canceled at the polarity inversion lines, however, the axial component becomes dominant there, allowing a more reliable determination of the original active-region chirality. We thus deduce that the hemispheric rule is far stronger than generally assumed, and cannot be explained by stochastic processes. Earlier studies have shown that the twist associated with the axial tilt of active regions is too small to account for the observed helicity; here, both tilt and twist are induced by the Coriolis force acting on the diverging flow in the emerging flux tube. However, in addition to this east-west expansion about the apex of the loop, each of its legs must expand continually in cross section during its rise through the convection zone, thereby acquiring a further twist through the Coriolis force. Since this transverse pressure effect is not limited by drag or tension forces, the final twist depends mainly on the rise time, and may be large enough to explain the observed active-region helicity.

  9. Light Bridge in a Developing Active Region. I. Observation of Light Bridge and its Dynamic Activity Phenomena

    NASA Astrophysics Data System (ADS)

    Toriumi, Shin; Katsukawa, Yukio; Cheung, Mark C. M.

    2015-10-01

    Light bridges, the bright structures that divide the umbra of sunspots and pores into smaller pieces, are known to produce a wide variety of activity events in solar active regions (ARs). It is also known that the light bridges appear in the assembling process of nascent sunspots. The ultimate goal of this series of papers is to reveal the nature of light bridges in developing ARs and the occurrence of activity events associated with the light bridge structures from both observational and numerical approaches. In this first paper, exploiting the observational data obtained by Hinode, the Interface Region Imaging Spectrograph, and the Solar Dynamics Observatory, we investigate the detailed structure of the light bridge in NOAA AR 11974 and its dynamic activity phenomena. As a result, we find that the light bridge has a weak, horizontal magnetic field, which is transported from the interior by a large-scale convective upflow and is surrounded by strong, vertical fields of adjacent pores. In the chromosphere above the bridge, a transient brightening occurs repeatedly and intermittently, followed by a recurrent dark surge ejection into higher altitudes. Our analysis indicates that the brightening is the plasma heating due to magnetic reconnection at lower altitudes, while the dark surge is the cool, dense plasma ejected from the reconnection region. From the observational results, we conclude that the dynamic activity observed in a light bridge structure such as chromospheric brightenings and dark surge ejections are driven by magnetoconvective evolution within the light bridge and its interaction with the surrounding magnetic fields.

  10. Chronic stress and moderate physical exercise prompt widespread common activation and limited differential activation in specific brain regions.

    PubMed

    Kim, Tae-Kyung; Han, Pyung-Lim

    2016-10-01

    Chronic stress in rodents produces depressive behaviors, whereas moderate physical exercise counteracts stress-induced depressive behaviors. Chronic stress and physical exercise appear to produce such opposing effects by changing the neural activity of specific brain regions. However, the detailed mechanisms through which the two different types of stimuli regulate brain function in opposite directions are not clearly understood. In the present study, we attempted to explore the neuroanatomical substrates mediating stress-induced behavioral changes and anti-depressant effects of exercise by examining stimulus-dependent c-Fos induction in the brains of mice that were exposed to repeated stress or exercise in a scheduled manner. Systematic and integrated analyses of c-Fos expression profiles indicated that various brain areas, including the prelimbic cortex, lateral septal area, and paraventricular nuclei of hypothalamus were commonly and strongly activated by both stress and exercise, while the lateral habenula and hippocampus were identified as being preferentially activated by stress and exercise, respectively. Exercise-dependent c-Fos expression in all regions examined in the brain occurred in both glutamatergic and GABAergic neurons. These results suggest that chronic stress and moderate exercise produce counteractive effects on mood behaviors, along with prompting widespread common activation and limited differential activation in specific brain regions. PMID:27539656

  11. Chronic stress and moderate physical exercise prompt widespread common activation and limited differential activation in specific brain regions.

    PubMed

    Kim, Tae-Kyung; Han, Pyung-Lim

    2016-10-01

    Chronic stress in rodents produces depressive behaviors, whereas moderate physical exercise counteracts stress-induced depressive behaviors. Chronic stress and physical exercise appear to produce such opposing effects by changing the neural activity of specific brain regions. However, the detailed mechanisms through which the two different types of stimuli regulate brain function in opposite directions are not clearly understood. In the present study, we attempted to explore the neuroanatomical substrates mediating stress-induced behavioral changes and anti-depressant effects of exercise by examining stimulus-dependent c-Fos induction in the brains of mice that were exposed to repeated stress or exercise in a scheduled manner. Systematic and integrated analyses of c-Fos expression profiles indicated that various brain areas, including the prelimbic cortex, lateral septal area, and paraventricular nuclei of hypothalamus were commonly and strongly activated by both stress and exercise, while the lateral habenula and hippocampus were identified as being preferentially activated by stress and exercise, respectively. Exercise-dependent c-Fos expression in all regions examined in the brain occurred in both glutamatergic and GABAergic neurons. These results suggest that chronic stress and moderate exercise produce counteractive effects on mood behaviors, along with prompting widespread common activation and limited differential activation in specific brain regions.

  12. A regional reconstruction of debris-flow activity in the Northern Calcareous Alps, Austria

    NASA Astrophysics Data System (ADS)

    Procter, Emily; Bollschweiler, Michelle; Stoffel, Markus; Neumann, Mathias

    2011-09-01

    Dendrogeomorphic dating of historical debris-flow events is a highly valuable tool for improving historical records in the field of natural hazard management. Previous dendrogeomorphic investigations generally have focused on case studies of single torrents; however, regional investigations may offer a more accurate reconstruction of regional patterns of activity and therefore may have an advantage over individual cases. The aim of the study is to provide a regional reconstruction of debris-flow events for a site in the Northern Calcareous Alps of western Austria (Gamperdonatal, Vorarlberg) and to document spatial and temporal morphological changes in individual and neighboring torrents. Analysis of 442 trees (268 Pinus mugo ssp. uncinata, 164 Picea abies, and 10 Abies alba) allowed identification of 579 growth disturbances corresponding to 63 debris-flow events since A.D. 1839. The majority of growth disturbances were in the form of growth suppression or release (76%) owing to the nature of both the deposited material and the process characteristics. Regional patterns of event frequency indicated a paucity of activity in the early to mid-twentieth century and increased activity since A.D. 1948, whereby large events were followed by subsequent years of continued activity of smaller magnitude. Patterns of frequency could be attributed primarily to spatiotemporal changes in channel morphology, but may also be reflective of changes in transport conditions within the valley. This study provides the first regional investigation in the Austrian Alps and contributes to the documentation of tree responses to geomorphic disturbances in calcareous material.

  13. p190RhoGAP has cellular RacGAP activity regulated by a polybasic region.

    PubMed

    Lévay, Magdolna; Bartos, Balázs; Ligeti, Erzsébet

    2013-06-01

    p190RhoGAP is a GTPase-activating protein (GAP) known to regulate actin cytoskeleton dynamics by decreasing RhoGTP levels through activation of the intrinsic GTPase activity of Rho. Although the GAP domain of p190RhoGAP stimulates the intrinsic' GTPase activity of several Rho family members (Rho, Rac, Cdc42) under in vitro conditions, p190RhoGAP is generally regarded as a GAP for RhoA in the cell. The cellular RacGAP activity of the protein has not been proven directly. We have previously shown that the in vitro RacGAP and RhoGAP activity of p190RhoGAP was inversely regulated through a polybasic region of the protein. Here we provide evidence that p190RhoGAP shows remarkable GAP activity toward Rac also in the cell. The cellular RacGAP activity of p190RhoGAP requires an intact polybasic region adjacent to the GAP domain whereas the RhoGAP activity is inhibited by the same domain. Our data indicate that through its alternating RacGAP and RhoGAP activity, p190RhoGAP plays a more complex role in the Rac-Rho antagonism than it was realized earlier.

  14. A Correlation Between Length of Strong-Shear Neutral Lines and Total X-Ray Brightness in Active Regions

    NASA Technical Reports Server (NTRS)

    Falconer, D. A.

    1997-01-01

    From a sample of 7 MSFC vector magnetograms,of active regions and 17 Yohkoh SXT soft X-ray images of these active regions, we have found that the total x-ray brightness of an entire active region is correlated with the total length of neutral lines on which the magnetic field is both strong (less than 250 G) and strongly sheared (shear angle greater than 75 deg) in the same active region. This correlation, if not fortuitous, is additional evidence of the importance of strong-shear strong-field neutral lines to strong heating in active regions.

  15. Effects of surfactant depletion on regional pulmonary metabolic activity during mechanical ventilation.

    PubMed

    de Prost, Nicolas; Costa, Eduardo L; Wellman, Tyler; Musch, Guido; Winkler, Tilo; Tucci, Mauro R; Harris, R Scott; Venegas, Jose G; Vidal Melo, Marcos F

    2011-11-01

    Inflammation during mechanical ventilation is thought to depend on regional mechanical stress. This can be produced by concentration of stresses and cyclic recruitment in low-aeration dependent lung. Positron emission tomography (PET) with (18)F-fluorodeoxyglucose ((18)F-FDG) allows for noninvasive assessment of regional metabolic activity, an index of neutrophilic inflammation. We tested the hypothesis that, during mechanical ventilation, surfactant-depleted low-aeration lung regions present increased regional (18)F-FDG uptake suggestive of in vivo increased regional metabolic activity and inflammation. Sheep underwent unilateral saline lung lavage and were ventilated supine for 4 h (positive end-expiratory pressure = 10 cmH(2)O, tidal volume adjusted to plateau pressure = 30 cmH(2)O). We used PET scans of injected (13)N-nitrogen to compute regional perfusion and ventilation and injected (18)F-FDG to calculate (18)F-FDG uptake rate. Regional aeration was quantified with transmission scans. Whole lung (18)F-FDG uptake was approximately two times higher in lavaged than in nonlavaged lungs (2.9 ± 0.6 vs. 1.5 ± 0.3 10(-3)/min; P < 0.05). The increased (18)F-FDG uptake was topographically heterogeneous and highest in dependent low-aeration regions (gas fraction 10-50%, P < 0.001), even after correction for lung density and wet-to-dry lung ratios. (18)F-FDG uptake in low-aeration regions of lavaged lungs was higher than that in low-aeration regions of nonlavaged lungs (P < 0.05). This occurred despite lower perfusion and ventilation to dependent regions in lavaged than nonlavaged lungs (P < 0.001). In contrast, (18)F-FDG uptake in normally aerated regions was low and similar between lungs. Surfactant depletion produces increased and heterogeneously distributed pulmonary (18)F-FDG uptake after 4 h of supine mechanical ventilation. Metabolic activity is highest in poorly aerated dependent regions, suggesting local increased inflammation.

  16. Comparison of the activity measurements in nuclear medicine services in the Brazilian northeast region.

    PubMed

    de Farias Fragoso, Maria da Conceição; de Albuquerque, Antônio Morais; de Oliveira, Mércia L; de Lima, Fabiana Farias; Barreto, Flávio Chiappetta Paes; de Andrade Lima, Ricardo

    2013-12-01

    The Northeastern Regional Centre for Nuclear Sciences (CRCN-NE), National Nuclear Energy Commission, has organized for the first time in nuclear medicine services (NMSs) in the Brazilian northeast region a comparison of activity measurements for (99m)Tc, (131)I, (67)Ga, (201)Tl and (57)Co. This tool is widely utilized to evaluate not only the accuracy of radionuclide calibrators, but also the competence of NMSs to measure the activity of the radiopharmaceuticals and the performance of the personnel involved in these measurements. The comparison results showed that 90% of the results received from participants are within the ±10% limit established by the Brazilian Norm.

  17. Magnetic Tilts and Polarity Separations in Sunspot Groups and Active Regions the Cycle 23

    NASA Astrophysics Data System (ADS)

    Zharkov, S. I.; Zharkova, V. V.

    2006-08-01

    We present the analysis of magnetic tilts in active regions and sunspot groups for 1996-2005 that are automatically extracted from the Solar Feature Catalogues (http://solar.inf.brad.ac.uk ). We investigate the statistical variations of magnetic field tilt in sunspot groups and whole active regions, their longitudinal and latitudinal distributions, drifts and daily polarity separation during different phases of the solar cycle 23. The classification results are compared with the similar research for the previous cycles and the specifics on the cycle 23 is discussed in conjunction to the solar dynamo theory.

  18. RESEARCH PAPER: A logistic model for magnetic energy storage in solar active regions

    NASA Astrophysics Data System (ADS)

    Wang, Hua-Ning; Cui, Yan-Mei; He, Han

    2009-06-01

    Previous statistical analyses of a large number of SOHO/MDI full disk longitudinal magnetograms provided a result that demonstrated how responses of solar flares to photospheric magnetic properties can be fitted with sigmoid functions. A logistic model reveals that these fitted sigmoid functions might be related to the free energy storage process in solar active regions. Although this suggested model is rather simple, the free energy level of active regions can be estimated and the probability of a solar flare with importance over a threshold can be forecast within a given time window.

  19. Real-Time CME Forecasting Using HMI Active-Region Magnetograms and Flare History

    NASA Technical Reports Server (NTRS)

    Falconer, David; Moore, Ron; Barghouty, Abdulnasser F.; Khazanov, Igor

    2011-01-01

    We have recently developed a method of predicting an active region s probability of producing a CME, an X-class Flare, an M-class Flare, or a Solar Energetic Particle Event from a free-energy proxy measured from SOHO/MDI line-of-sight magnetograms. This year we have added three major improvements to our forecast tool: 1) Transition from MDI magnetogram to SDO/HMI magnetogram allowing us near-real-time forecasts, 2) Automation of acquisition and measurement of HMI magnetograms giving us near-real-time forecasts (no older than 2 hours), and 3) Determination of how to improve forecast by using the active region s previous flare history in combination with its free-energy proxy. HMI was turned on in May 2010 and MDI was turned off in April 2011. Using the overlap period, we have calibrated HMI to yield what MDI would measure. This is important since the value of the free-energy proxy used for our forecast is resolution dependent, and the forecasts are made from results of a 1996-2004 database of MDI observations. With near-real-time magnetograms from HMI, near-real-time forecasts are now possible. We have augmented the code so that it continually acquires and measures new magnetograms as they become available online, and updates the whole-sun forecast from the coming day. The next planned improvement is to use an active region s previous flare history, in conjunction with its free-energy proxy, to forecast the active region s event rate. It has long been known that active regions that have produced flares in the past are likely to produce flares in the future, and that active regions that are nonpotential (have large free-energy) are more likely to produce flares in the future. This year we have determined that persistence of flaring is not just a reflection of an active region s free energy. In other words, after controlling for free energy, we have found that active regions that have flared recently are more likely to flare in the future.

  20. Lightning activity variation during the evolution of tropical cyclones in the southwest Pacific region

    NASA Astrophysics Data System (ADS)

    Chandra, A.; Kumar, S.; Kumar, A.

    2015-12-01

    The South Pacific Island countries are vulnerable to natural hazards which cause devastating effects on infrastructure, crops and at times loss of lives and many others. Tropical cyclones (TCs) are one type of natural hazard experienced by Pacific Island countries (PICs). The South Pacific region has two seasons, namely: the cyclone season, running from November to April, and the non-cyclone season, running from May to October. Tropical cyclones are associated with strong winds, rainfall, and thunderstorms generating strong lightning discharges. The analysis of lightning data obtained from the World Wide Lightning Locations Network for the southwest Pacific region, defined as the region bounded between geographic coordinates, latitudes 0 - 40°S, longitudes 135°E - 120°W, during 2013 clearly shows the lightning activity to be higher during the cyclone season due to increased convective activity. The change in the lightning activity with the intensity of 41 TCs of categories 2 to 5 occurring in the southwest Pacific region has been analysed for the years 2005 to 2013. The intensity measurements, as determined by maximum sustained winds and the lightning activity, as determined by flash counts were studied during the stages of evolution of these TCs. Taking into account the lag between peak lightning activity and peak maximum sustained wind, the two quantities; lightning activity and intensity for individual TCs were correlated. Square 10° grid sizes were used along with radial sections to quantify lightning. We quantify lightning occurrences in three distinct sections of the cyclone (eyewall, inner and outer rainbands) to clearly show the lightning characteristics within these different regions. Lightning activity is seen to be greatly variable between different storms, however we do observe lightning outbreaks in the eyewall prior to the intensification of the storm.

  1. IFLA General Conference, 1992. Division of Regional Activities: Section on Africa; Section on Asia/Oceania; Section on Latin America and the Caribbean. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations and Institutions, London (England).

    Seven papers delivered at the 1992 International Federation of Library Associations and Institutions annual meeting relating to regional activities are presented. These papers deal with library issues in Africa, Asia and Oceania, Latin America, and the Caribbean. The papers are: (1) "Designing National Information Policies in African: Process and…

  2. Forward modeling transient brightenings and microflares around an active region observed with Hi-C

    SciTech Connect

    Kobelski, Adam R.; McKenzie, David E.

    2014-10-20

    Small-scale flare-like brightenings around active regions are among the smallest and most fundamental of energetic transient events in the corona, providing a testbed for models of heating and active region dynamics. In a previous study, we modeled a large collection of these microflares observed with Hinode/X-Ray Telescope (XRT) using EBTEL and found that they required multiple heating events, but could not distinguish between multiple heating events on a single strand, or multiple strands each experiencing a single heating event. We present here a similar study, but with extreme-ultraviolet data of Active Region 11520 from the High Resolution Coronal Imager (Hi-C) sounding rocket. Hi-C provides an order of magnitude improvement to the spatial resolution of XRT, and a cooler temperature sensitivity, which combine to provide significant improvements to our ability to detect and model microflare activity around active regions. We have found that at the spatial resolution of Hi-C (≈0.''3), the events occur much more frequently than expected (57 events detected, only 1 or 2 expected), and are most likely made from strands of the order of 100 km wide, each of which is impulsively heated with multiple heating events. These findings tend to support bursty reconnection as the cause of the energy release responsible for the brightenings.

  3. Action sentences activate sensory motor regions in the brain independently of their status of reality.

    PubMed

    de Vega, Manuel; León, Inmaculada; Hernández, Juan A; Valdés, Mitchell; Padrón, Iván; Ferstl, Evelyn C

    2014-07-01

    Some studies have reported that understanding concrete action-related words and sentences elicits activations of motor areas in the brain. The present fMRI study goes one step further by testing whether this is also the case for comprehension of nonfactual statements. Three linguistic structures were used (factuals, counterfactuals, and negations), referring either to actions or, as a control condition, to visual events. The results showed that action sentences elicited stronger activations than visual sentences in the SMA, extending to the primary motor area, as well as in regions generally associated with the planning and understanding of actions (left superior temporal gyrus, left and right supramarginal gyri). Also, we found stronger activations for action sentences than for visual sentences in the extrastriate body area, a region involved in the visual processing of human body movements. These action-related effects occurred not only in factuals but also in negations and counterfactuals, suggesting that brain regions involved in action understanding and planning are activated by default even when the actions are described as hypothetical or as not happening. Moreover, some of these regions overlapped with those activated during the observation of action videos, indicating that the act of understanding action language and that of observing real actions share neural networks. These results support the claim that embodied representations of linguistic meaning are important even in abstract linguistic contexts.

  4. Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER

    PubMed Central

    Suchiman, H. Eka D.; Slieker, Roderick C.; Kremer, Dennis; Slagboom, P. Eline; Heijmans, Bastiaan T.; Tobi, Elmar W.

    2015-01-01

    EpiTYPER® is a mass spectrometry-based bisulfite sequencing method that enables region-specific DNA methylation analysis in a quantitative and high-throughput fashion. The technology targets genomic regions of 100–600 base pairs and results in the quantitative measurement of DNA methylation levels largely at single-nucleotide resolution. It is particularly suitable for larger scale efforts to study candidate regions or to validate regions from genome-wide DNA methylation studies. Here, we describe in detail how to design and perform EpiTYPER measurements and preprocess the data, providing details for high quality measurements not provided in the standard EpiTYPER protocol. PMID:26442105

  5. Hippocampal sub-regional shape and physical activity in older adults.

    PubMed

    Varma, Vijay R; Tang, Xiaoying; Carlson, Michelle C

    2016-08-01

    Hippocampal atrophy is a hallmark of Alzheimer's disease pathology, and a target biomarker region for testing intervention efficacy. Over the last few decades, a growing body of evidence from animal and human models suggests that physical activity (PA) is associated with structural benefits to the hippocampus in older adults. Very few human studies, however have explored hippocampal sub-regional specificity of PA; this is significant considering that sub-regions of the hippocampus are associated with distinct cognitive tasks and are differentially affected by disease pathology. This study used objective and self-reported measures of daily walking activity and exercise, and surface-based regional shape analysis using high-field hippocampal sub-regional partitions to explore sub-region specific hippocampal associations in a sample of nondemented, community-dwelling older adults at elevated sociodemographic risk for cognitive decline. Vertex-wise surface areas, which may be more sensitive than global volume measures, were calculated using shape diffeomorphometry, and PA was assessed using step activity monitors and PA questionnaires. We found that daily walking activity in a participant's environment was associated in cross-section mainly with larger surface areas of the subiculum in women. Associations remained significant when controlling for self-reported exercise. Prior studies have found that PA related to exercise and aerobic fitness may be most closely associated with the anterior hippocampus, particularly the dentate gyrus of the hippocampus. These novel findings are the first, to our knowledge, in human models to suggest that PA related to navigation that may not reach the level of moderate-intensity exercise may be associated with specific sub-regions of the hippocampus. These findings underscore the importance of better understanding the independent and related biological mechanisms and pathways by which increasing exercise as well as non

  6. Genomic Regions Associated with Multiple Sclerosis Are Active in B Cells

    PubMed Central

    Disanto, Giulio; Sandve, Geir Kjetil; Berlanga-Taylor, Antonio J.; Morahan, Julia M.; Dobson, Ruth; Giovannoni, Gavin; Ramagopalan, Sreeram V.

    2012-01-01

    More than 50 genomic regions have now been shown to influence the risk of multiple sclerosis (MS). However, the mechanisms of action, and the cell types in which these associated variants act at the molecular level remain largely unknown. This is especially true for associated regions containing no known genes. Given the evidence for a role for B cells in MS, we hypothesized that MS associated genomic regions co-localized with regions which are functionally active in B cells. We used publicly available data on 1) MS associated regions and single nucleotide polymorphisms (SNPs) and 2) chromatin profiling in B cells as well as three additional cell types thought to be unrelated to MS (hepatocytes, fibroblasts and keratinocytes). Genomic intervals and SNPs were tested for overlap using the Genomic Hyperbrowser. We found that MS associated regions are significantly enriched in strong enhancer, active promoter and strong transcribed regions (p = 0.00005) and that this overlap is significantly higher in B cells than control cells. In addition, MS associated SNPs also land in active promoter (p = 0.00005) and enhancer regions more than expected by chance (strong enhancer p = 0.0006; weak enhancer p = 0.00005). These results confirm the important role of the immune system and specifically B cells in MS and suggest that MS risk variants exert a gene regulatory role. Previous studies assessing MS risk variants in T cells may be missing important effects in B cells. Similar analyses in other immunological cell types relevant to MS and functional studies are necessary to fully elucidate how genes contribute to MS pathogenesis. PMID:22396755

  7. Design of electro-active polymer gels as actuator materials

    NASA Astrophysics Data System (ADS)

    Popovic, Suzana

    Smart materials, alternatively called active or adaptive, differ from passive materials in their sensing and activation capability. These materials can sense changes in environment such as: electric field, magnetic field, UV light, pH, temperature. They are capable of responding in numerous ways. Some change their stiffness properties (electro-rheological fluids), other deform (piezos, shape memory alloys, electrostrictive materials) or change optic properties (electrochromic polymers). Polymer gels are one of such materials which can change the shape, volume and even optical properties upon different applied stimuli. Due to their low stiffness property they are capable of having up to 100% of strain in a short time, order of seconds. Their motion resembles the one of biosystems, and they are often seen as possible artificial muscle materials. Despite their delicate nature, appropriate design can make them being used as actuator materials which can form controllable surfaces and mechanical switches. In this study several different groups of polymer gel material were investigated: (a) acrylamide based gels are sensitive to pH and electric field and respond in volume change, (b) polyacrylonitrile (PAN) gel is sensitive to pH and electric field and responds in axial strain and bending, (c) polyvinylalcohol (PVA) gel is sensitive to electric field and responds in axial strain and bending and (d) perfluorinated sulfonic acid membrane, Nafion RTM, is sensitive to electric field and responds in bending. Electro-mechanical and chemo-mechanical behavior of these materials is a function of a variety of phenomena: polymer structure, affinity of polymer to the solvent, charge distribution within material, type of solvent, elasticity of polymer matrix, etc. Modeling of this behavior is a task aimed to identify what is driving mechanism for activation and express it in a quantitative way in terms of deformation of material. In this work behavior of the most promising material as

  8. De novo design of protein kinase inhibitors by in silico identification of hinge region-binding fragments.

    PubMed

    Urich, Robert; Wishart, Grant; Kiczun, Michael; Richters, André; Tidten-Luksch, Naomi; Rauh, Daniel; Sherborne, Brad; Wyatt, Paul G; Brenk, Ruth

    2013-05-17

    Protein kinases constitute an attractive family of enzyme targets with high relevance to cell and disease biology. Small molecule inhibitors are powerful tools to dissect and elucidate the function of kinases in chemical biology research and to serve as potential starting points for drug discovery. However, the discovery and development of novel inhibitors remains challenging. Here, we describe a structure-based de novo design approach that generates novel, hinge-binding fragments that are synthetically feasible and can be elaborated to small molecule libraries. Starting from commercially available compounds, core fragments were extracted, filtered for pharmacophoric properties compatible with hinge-region binding, and docked into a panel of protein kinases. Fragments with a high consensus score were subsequently short-listed for synthesis. Application of this strategy led to a number of core fragments with no previously reported activity against kinases. Small libraries around the core fragments were synthesized, and representative compounds were tested against a large panel of protein kinases and subjected to co-crystallization experiments. Each of the tested compounds was active against at least one kinase, but not all kinases in the panel were inhibited. A number of compounds showed high ligand efficiencies for therapeutically relevant kinases; among them were MAPKAP-K3, SRPK1, SGK1, TAK1, and GCK for which only few inhibitors are reported in the literature.

  9. Toward an SSC test lattice design with two chromatic clusters of interaction regions

    SciTech Connect

    Garren, A.; Steffen, K.

    1985-10-01

    Various ideas on how to design a cluster of interaction regions (IR) with local chromaticity correction were investigated, all of them employing pairs of sextupoles with betatron phase advances of (2n+{lambda}){pi} between them so that their geometric aberrations cancel. Some of these ideas were discarded. Even when, at the sextupoles, one amplitude function is made very small as compared to the other, and the two interleaving pairs are thus decoupled regarding their horizontal and vertical chromaticity correction, they can still not be considered `non-interleaved` regarding their compensation of chromatic aberrations. What remains, then, are schemes that have one or more complete sextupole pairs in a periodic focusing structure between interaction points. This periodic structure may be specially tailored to suit the purpose, or it may even be the normal arc FODO structure. In any case, it must have a strong horizontal dispersion for the sextupoles to act on. Probably the best and most elegant structure the authors found is the one described at the end of this note; it has a 2200 m long periodic channel of arc cells with four pairs of sextupoles between interaction points. In this scheme, the three interaction points forming a `cluster` are within five miles of each other, and thus the denotation may still be justified. However, the FODO channels may be increased in this scheme to any length, until an equidistant spacing of IR`s is obtained. The elegance of the scheme lies in the way the vertical separation and the horizontal and vertical dispersions are handled at the end of the FODO channel and matched into the interaction region, and it is applicable to clustered as well as distributed IR`s. However at first a simpler scheme will be described which has only one pair of sextupoles between IR`s, placed in a specially tailored FODO channel with long cells and very large dispersion.

  10. Active space debris removal—A preliminary mission analysis and design

    NASA Astrophysics Data System (ADS)

    Castronuovo, Marco M.

    2011-11-01

    The active removal of five to ten large objects per year from the low Earth orbit (LEO) region is the only way to prevent the debris collisions from cascading. Among the three orbital regions near the Earth where most catastrophic collisions are predicted to occur, the one corresponding to a sun-synchronous condition is considered the most relevant. Forty-one large rocket bodies orbiting in this belt have been identified as the priority targets for removal. As part of a more comprehensive system engineering solution, a space mission dedicated to the de-orbiting of five rocket bodies per year from this orbital regime has been designed. The selected concept of operations envisages the launch of a satellite carrying a number of de-orbiting devices, such as solid propellant kits. The satellite performs a rendezvous with an identified object and mates with it by means of a robotic arm. A de-orbiting device is attached to the object by means of a second robotic arm, the object is released and the device is activated. The spacecraft travels then to the next target. The present paper shows that an active debris removal mission capable of de-orbiting 35 large objects in 7 years is technically feasible, and the resulting propellant mass budget is compatible with many existing platforms.

  11. Optimal portfolio design to reduce climate-related conservation uncertainty in the Prairie Pothole Region.

    PubMed

    Ando, Amy W; Mallory, Mindy L

    2012-04-24

    Climate change is likely to alter the spatial distributions of species and habitat types but the nature of such change is uncertain. Thus, climate change makes it difficult to implement standard conservation planning paradigms. Previous work has suggested some approaches to cope with such uncertainty but has not harnessed all of the benefits of risk diversification. We adapt Modern Portfolio Theory (MPT) to optimal spatial targeting of conservation activity, using wetland habitat conservation in the Prairie Pothole Region (PPR) as an example. This approach finds the allocations of conservation activity among subregions of the planning area that maximize the expected conservation returns for a given level of uncertainty or minimize uncertainty for a given expected level of returns. We find that using MPT instead of simple diversification in the PPR can achieve a value of the conservation objective per dollar spent that is 15% higher for the same level of risk. MPT-based portfolios can also have 21% less uncertainty over benefits or 6% greater expected benefits than the current portfolio of PPR conservation. Total benefits from conservation investment are higher if returns are defined in terms of benefit-cost ratios rather than benefits alone. MPT-guided diversification can work to reduce the climate-change-induced uncertainty of future ecosystem-service benefits from many land policy and investment initiatives, especially when outcomes are negatively correlated between subregions of a planning area. PMID:22451914

  12. Optimal portfolio design to reduce climate-related conservation uncertainty in the Prairie Pothole Region.

    PubMed

    Ando, Amy W; Mallory, Mindy L

    2012-04-24

    Climate change is likely to alter the spatial distributions of species and habitat types but the nature of such change is uncertain. Thus, climate change makes it difficult to implement standard conservation planning paradigms. Previous work has suggested some approaches to cope with such uncertainty but has not harnessed all of the benefits of risk diversification. We adapt Modern Portfolio Theory (MPT) to optimal spatial targeting of conservation activity, using wetland habitat conservation in the Prairie Pothole Region (PPR) as an example. This approach finds the allocations of conservation activity among subregions of the planning area that maximize the expected conservation returns for a given level of uncertainty or minimize uncertainty for a given expected level of returns. We find that using MPT instead of simple diversification in the PPR can achieve a value of the conservation objective per dollar spent that is 15% higher for the same level of risk. MPT-based portfolios can also have 21% less uncertainty over benefits or 6% greater expected benefits than the current portfolio of PPR conservation. Total benefits from conservation investment are higher if returns are defined in terms of benefit-cost ratios rather than benefits alone. MPT-guided diversification can work to reduce the climate-change-induced uncertainty of future ecosystem-service benefits from many land policy and investment initiatives, especially when outcomes are negatively correlated between subregions of a planning area.

  13. Development of a systematic and practical methodology for the design of vehicles semi-active suspension control system

    NASA Astrophysics Data System (ADS)

    Bolandhemmat, Hamidreza; Clark, Christopher M.; Golnaraghi, Farid

    2010-05-01

    In this paper, a novel systematic and practical methodology is presented for design of vehicle semi-active suspension systems. Typically, the semi-active control strategies developed to improve vehicle ride comfort and stability have a switching nature. This makes the design of the controlled suspension systems difficult and highly dependent on an extensive trial-and-error process. The proposed methodology maps the discontinuous control system model to a continuous linear region, where all the time and frequency design techniques, established in the conventional control system theory, can be applied. If the semi-active control system is designed to satisfy some ride and stability requirements, an inverse mapping offers the ultimate control law. At the end, the entire design procedure is summarised in six steps. The effectiveness of the proposed methodology in the design of a semi-active suspension system for a Cadillac SRX 2005 is demonstrated with road tests results. Real-time experiments confirm that the use of the newly developed systematic design method reduces the required time and effort in real industrial problems.

  14. Conceptual design of a regional water quality screening model. [RFF; Reach; HANFORD; ARQUAL; SEAS; NASQUAN

    SciTech Connect

    Davis, M J

    1981-01-01

    This water quality assessment methodology is intended to predict concentrations at future times and to estimate the impacts on water quality of energy-related activities (including industrial boilers). Estimates of impacts on water quality at future times are based on incremental changes in pollutant inputs to the body water. Important features of the model are: use of measured concentrations to account for existing conditions; consideration of incremental changes in pollutant loads; emphasis on the energy sector and industrial boilers; analysis restricted to streams only; no attempt to fully account for pollutant behavior; and flexible design, so that future improvements can be incorporated. The basic approach is very similar to the one used by Argonne's ARQUAL model but will allow more complex pollutant behavior and more flexibility in use. (PSB)

  15. Active deformation analysis and evaluation of earthquake hazard in Gafsa region (Southern Atlas of Tunisia)

    NASA Astrophysics Data System (ADS)

    Bahrouni, Nejib; Bouaziz, Samir; Soumaya, Abdelkader; Ben Ayed, Noureddine; Attafi, Khereddine

    2013-04-01

    The Southern Atlas of Tunisia constitutes the transition between Atlas fold and the Northern edge of the Saharan platform. The general direction is near to E-W deflected to N060 whose structural style and geometry of deformation still complex. This domain is Southern part of the seismic zone bordering the Northern African plate as indicated by the large seismic events that occurred periodically. The Gafsa area, more particularly concerned by seismic risk, is bordered to the North by the NW-SE trending "Gafsa Fault" and has significant seismic. The most active tectonic are related to the reactivating of pre-existing NW-SE and E-W trending strike-slip faulting. We will set up the network in the active zone of Gafsa surroundings, in order to cover the area of aftershocks (co-seismic surface rupture) of May 22, 1972 and December 27, 1985 (Ms=4.2) in Gafsa and November 7, 1989 (Ms=4.4) in Metlaoui, December 8, 2010 and in Sidi Aich (Ms=3.66). Paleostress and calculated focal mechanism solutions for the earthquakes show that the active stress field is a NW-SE trending compression. Damage and surface effects of land and urban areas caused by these events demonstrate the vulnerability of cities in the region of Gafsa to seismic activities. The analyses of recent and active deformation in this region has allowed the assessment of urban seismic hazard and take stock seismic zones embedded in a distorted geographic information system (GIS) in close relationship with the regional tectonic setting. This assessment has provided crucial information on the neotectonic deformation and seismotectonics of Gafsa region and its surrounding which affects remote orogenic dynamics and the current state of the North African margin. In particular, the comparison between the deformations and quantified seismic activity has also assessed the risk and the regional seismic hazard and develop a seismotectonic zoning.

  16. Aerodynamic characteristics of a rotorcraft airfoil designed for the tip region of a main rotor blade

    NASA Technical Reports Server (NTRS)

    Noonan, Kevin W.

    1991-01-01

    A wind tunnel investigation was conducted to determine the 2-D aerodynamic characteristics of a new rotorcraft airfoil designed for application to the tip region (stations outboard of 85 pct. radius) of a helicopter main rotor blade. The new airfoil, the RC(6)-08, and a baseline airfoil, the RC(3)-08, were investigated in the Langley 6- by 28-inch transonic tunnel at Mach numbers from 0.37 to 0.90. The Reynolds number varied from 5.2 x 10(exp 6) at the lowest Mach number to 9.6 x 10(exp 6) at the highest Mach number. Some comparisons were made of the experimental data for the new airfoil and the predictions of a transonic, viscous analysis code. The results of the investigation indicate that the RC(6)-08 airfoil met the design goals of attaining higher maximum lift coefficients than the baseline airfoil while maintaining drag divergence characteristics at low lift and pitching moment characteristics nearly the same as those of the baseline airfoil. The maximum lift coefficients of the RC(6)-08 varied from 1.07 at M=0.37 to 0.94 at M=0.52 while those of the RC(3)-08 varied from 0.91 to 0.85 over the same Mach number range. At lift coefficients of -0.1 and 0, the drag divergence Mach number of both the RC(6)-08 and the RC(3)-08 was 0.86. The pitching moment coefficients of the RC(6)-08 were less negative than those of the RC(3)-08 for Mach numbers and lift coefficients typical of those that would occur on a main rotor blade tip at high forward speeds on the advancing side of the rotor disk.

  17. Altered Intrinsic Regional Activity and Interregional Functional Connectivity in Post-stroke Aphasia

    PubMed Central

    Yang, Mi; Li, Jiao; Li, Yibo; Li, Rong; Pang, Yajing; Yao, Dezhong; Liao, Wei; Chen, Huafu

    2016-01-01

    Several neuroimaging studies have examined cerebral function in patients who suffer from aphasia, but the mechanism underlying this disorder remains poorly understood. In this study, we examined alterations in the local regional and remote interregional network cerebral functions in aphasia combined with amplitude of low-frequency fluctuations and interregional functional connectivity (FC) using resting-state functional magnetic resonance imaging. A total of 17 post-stroke aphasic patients, all having suffered a stroke in the left hemisphere, as well as 20 age- and sex-matched healthy controls, were enrolled in this study. The aphasic patients showed significantly increased intrinsic regional activity mainly in the contralesional mesial temporal (hippocampus/parahippocampus, [HIP/ParaHIP]) and lateral temporal cortices. In addition, intrinsic regional activity in the contralesional HIP/ParaHIP was negatively correlated with construction score. Aphasic patients showed increased remote interregional FC between the contralesional HIP/ParaHIP and fusiform gyrus, but reduced FC in the ipsilesional occipital and parietal cortices. These findings suggested that the intrinsic regional brain dysfunctions in aphasia were related to interregional functional connectivity. Changes in the intrinsic regional brain activity and associated remote functional connectivity pattern would provide valuable information to enhance the understanding of the pathophysiological mechanisms of aphasia. PMID:27091494

  18. GPS constraints on active deformation in the Isparta Angle region of SW Turkey

    NASA Astrophysics Data System (ADS)

    Tiryakioğlu, İbrahim; Floyd, Michael; Erdoğan, Saffet; Gülal, Engin; Ergintav, Semih; McClusky, Simon; Reilinger, Robert

    2013-12-01

    We use survey and continuous GPS observations during the period 1997-2010 to investigate active deformation in the Isparta Angle region of SW Anatolia, Turkey. This region, bordered by the Fethiye Burdur Fault Zone (FBFZ) in the west and the SE extension of the Aksehir Simav Fault Zone (AKSFZ) in the east, accommodates a part of the active deformation of W Turkey. Our results show that the Isparta Angle region rotates counter-clockwise (CCW) with respect to Anatolia. Both the FBFZ and the AKSFZ are predominantly transtensional boundaries that accommodate southward motion of the Isparta region with respect to Anatolia. The FBFZ has left-lateral strike-slip behaviour along its SW segment that changes to right-lateral strike-slip along its NE extension. This change in the sense of strike-slip motion is accommodated by extension on a NW-SE striking normal fault system that is associated with the Menderes Graben system. Transtensional fault systems along the boundaries of the Isparta Angle with Anatolia are inconsistent with extrusion models for present-day southward motion. An increase in motion rates towards the Hellenic and Cyprus arc subduction systems, and CCW of the Isparta region, supports dynamic models involving active rollback of the subducting African Plate, toroidal mantle flow around the eastern edge of the subducting African slab near the Hellenic arc/Florence Rise junction, and/or gravitational collapse of the overriding Anatolia Plate.

  19. Phospholipase A2-like activity of human bocavirus VP1 unique region.

    PubMed

    Qu, Xiao-Wang; Liu, Wen-Pei; Qi, Zheng-Yu; Duan, Zhao-Jun; Zheng, Li-Shu; Kuang, Zi-Zhou; Zhang, Wan-Ju; Hou, Yun-De

    2008-01-01

    Human bocavirus (HBoV) is a new parvovirus first discovered in 2005, which is associated with acute respiratory infection. Analysis of sequence homology has revealed that a putative phospholipase A2 (PLA2) motif exists in the VP1 unique region of HBoV. However, little is known about whether the VP1 unique region of HBoV has PLA2 enzymatic activity and how these critical residues contribute to its PLA2 activity. To address these issues, the VP1 unique region protein and four of its mutants, were expressed in Eschericha coli. The purified VP1 unique protein (VP1U) showed a typical Ca2+-dependent secreted PLA2-like (sPLA2) activity, which was inhibited by sPLA2-specific inhibitors in a time-dependent manner. Mutation of one of the amino acids (21Pro, 41His, 42Asp or 63Asp) in VP1U almost eliminated the sPLA2 activity of HBoV VP1U. These data indicate that VP1U of HBoV has sPLA2-like enzymatic activity, and these residues are crucial for its sPLA2-like activity. Potentially, VP1U may be a target for the development of anti-viral drugs for HBoV.

  20. Differential Activation Patterns in the Same Brain Region Led to Opposite Emotional States.

    PubMed

    Shibata, Kazuhisa; Watanabe, Takeo; Kawato, Mitsuo; Sasaki, Yuka

    2016-09-01

    In human studies, how averaged activation in a brain region relates to human behavior has been extensively investigated. This approach has led to the finding that positive and negative facial preferences are represented by different brain regions. However, using a functional magnetic resonance imaging (fMRI) decoded neurofeedback (DecNef) method, we found that different patterns of neural activations within the cingulate cortex (CC) play roles in representing opposite directions of facial preference. In the present study, while neutrally preferred faces were presented, multi-voxel activation patterns in the CC that corresponded to higher (or lower) preference were repeatedly induced by fMRI DecNef. As a result, previously neutrally preferred faces became more (or less) preferred. We conclude that a different activation pattern in the CC, rather than averaged activation in a different area, represents and suffices to determine positive or negative facial preference. This new approach may reveal the importance of an activation pattern within a brain region in many cognitive functions.