Science.gov

Sample records for activities linking science

  1. Linking Science and Literacy

    ERIC Educational Resources Information Center

    Plummer, Donna M.; Davis, Betty Jo; Brazier, Victoria

    2011-01-01

    We successfully integrated science and language arts in a third-grade classroom. The students used "scientist's eyes" and "poet's eyes" to write original poetry. In addition, they created habitat posters about a swamp organism. Scoring guides for the habitat poems and posters are also included. (Contains 5 figures and 2 tables.)

  2. Undergraduate Projects Linking Science, Technology and Society. Interdisciplinary Programs and Activities, 1986-87. Interactions:8.

    ERIC Educational Resources Information Center

    Schachterle, Lance E., Ed.; Shanahan, Joan M., Ed.

    In 1970, Worcester Polytechnic Institute (WPI) radically revised its curriculum by replacing specific course distributions with a new program, emphasizing projects at various levels. In instituting this change, faculty were especially concerned to encourage engineering, science, and management students to recognize how their professional work…

  3. From Thoughts To Action - Linking Practice, Science, Policy And Decision Making: Dissemination Activities Of The Global Risk Forum, GRF Davos

    NASA Astrophysics Data System (ADS)

    Stal, Marc; Sutter, Corina; Ammann, Walter

    2010-05-01

    The world's growing population in combination with expanding urbanisation, globalisation and climate change has greatly aggravated the risk potential to all communities and nations. These increasing risks imply the intensification of worldwide disasters, hence collaborations and worldwide knowledge exchange to mitigate these negative impacts is mandatory. How can these exchange and collaboration activities take place? The Global Risk Forum, GRF Davos addresses the variety of risks that face communities with a special focus on climate change, natural hazards, environmental degradation as well as technical, biological risks, pandemics and terrorism - all across different political institutions, national and international organisations, countries and business sectors. One of GRF's main goals is to bridge the gap between science and practice and to promote and accelerate the worldwide exchange of know-how and experience. GRF Davos aims at targeting solutions and promoting good practice in integral risk management and climate change adaptation.. The Forum also provides and manages a network for decision-makers, practitioners and experts from politics, government, IGOs, business, science, NGOs, media and the public and works on maintaining and expanding these networks constantly to enable the dissemination of disaster and risk reduction techniques. In order to link practice, science, policy and decision making, GRF Davos has three pillars, the Risk Academy, the International Disaster and Risk Conferences and Workshops (IDRC) as well as the online Platform for Networks. With its pillars, the GRFs aims at reducing vulnerability for all types of risks and disasters to protect life, property, environment, critical infrastructure and all means of business for the worldwide community on a sustainable basis.

  4. Educational Psychology: Linking Science to Design.

    ERIC Educational Resources Information Center

    Block, Karen K.

    This paper explores the concept of educational psychology as a "linking science" between (1) theory and research in psychology and learning and (2) the educational arena of the schools. A linking science is defined as a special structure that intervenes between scientific theory and practical application. The author's first major point is that a…

  5. Linking Science Education to the Workplace

    NASA Astrophysics Data System (ADS)

    Hurd, Paul Dehart

    1998-12-01

    This article examines the issue of linking education in the sciences with the world of work for all students. Traditionally, science teaching has been limited to preparing student for research career in science at the university level. The reform movement in science education is focused on intellectual skills that serve to fortify the human capital of all students and the economic productivity of the nation. The educational issue arises from evolutionary changes that are taking place in the practice of science, the development of a global economy, the nation's entrance into an Information Age, and the changing nature of the workplace. To identify and integrate these factors in the practice of science teaching is the goal of this article.

  6. Emotionally Intense Science Activities

    ERIC Educational Resources Information Center

    King, Donna; Ritchie, Stephen; Sandhu, Maryam; Henderson, Senka

    2015-01-01

    Science activities that evoke positive emotional responses make a difference to students' emotional experience of science. In this study, we explored 8th Grade students' discrete emotions expressed during science activities in a unit on Energy. Multiple data sources including classroom videos, interviews and emotion diaries completed at the end of…

  7. The science teacher as the organic link

    NASA Astrophysics Data System (ADS)

    Alexakos, Konstantinos

    2007-10-01

    This study began as an exploration of the following questions: What do individual science teachers bring into their teaching that frames and mediates their teaching philosophy and of what, if any, value is it in science education? Drawing from a life history case study of Anna, an in-service science teacher, I show that her moral beliefs, perceptions, experiences, and interests dialectically frame and mediate her views of science teaching. Anna brings into her classroom her personal philosophy of teaching and learning. This is in contrast to studies concluding that different aspects of teachers' personal philosophies, such as their understanding of the nature of science and their behavior and pedagogical decisions are not connected and may be neatly segregated from one another. In the "transmission" [Transmission is presented in quotes because in this manuscript it is used dialectically, as opposed to a one-directional and "objective" process. The science teacher is not just a "lens" for the transmission of cultural capital; the cultural capital "transmitted" though Anna is seen as existing in a state of creation/recreation.] of cultural capital, Anna embodies dialectical relationships and processes, not just as a mediator of culture, but also as an organic entity that contributes to how culture is created, recreated and exchanged in a science classroom, and as such, is referred to here as an organic link. Science teacher identity and science teaching philosophy are thus seen as much closer to the human experience—merging the intellectual, the personal, the cultural, the political, and the environmental with the relationships and the processes that connect each to the others and to the whole. They are viewed as, at once, being mediated by as well as mediating one another. I argue that the total of what science teaching is exceeds the sum of its commonly "measurable" parts, like content and pedagogical knowledge. Although the designing and framing of this study

  8. Linking Science Fiction and Physics Courses

    NASA Astrophysics Data System (ADS)

    McBride, Krista K.

    2016-05-01

    Generally, cohorts or learning communities enrich higher learning in students. Learning communities consist of conventionally separate groups of students that meet together with common academic purposes and goals. Types of learning communities include paired courses with concurrent student enrollment, living-learning communities, and faculty learning communities. This article discusses a learning community of 21 students that I created with a colleague in the English department. The community encompasses two general education courses: an algebra-based physics course entitled "Intro to Physics" and a literature course entitled "Science Fiction, Science Fact." Students must enroll in both of these courses during the same semester. Additionally, I highlight advantages to linking these courses through surveying the assignments and course materials that we used in our learning community. Figure 1 shows the topics that are covered in both physics and literature courses.

  9. Science World Activities Book.

    ERIC Educational Resources Information Center

    Wisconsin Academy of Sciences, Arts and Letters, Madison.

    This document consists of three sections. Section I contains 19 activities developed by master teachers for the Science World '84 summer science program. These activities focus on studies involving airplane controls, trash bag kites, computers, meteorology, compass orienteering, soils, aquatic ecosystems, bogs, and others. Objectives, materials…

  10. WFIRST Project Science Activities

    NASA Technical Reports Server (NTRS)

    Gehrels, Neil

    2012-01-01

    The WFIRST Project is a joint effort between GSFC and JPL. The project scientists and engineers are working with the community Science Definition Team to define the requirements and initial design of the mission. The objective is to design an observatory that meets the WFIRST science goals of the Astr02010 Decadal Survey for minimum cost. This talk will be a report of recent project activities including requirements flowdown, detector array development, science simulations, mission costing and science outreach. Details of the interim mission design relevant to scientific capabilities will be presented.

  11. Linking General Education and Science Teacher Preparation

    ERIC Educational Resources Information Center

    Talanquer, Vicente; Morgan, Del; Maeyer, Jenine; Young, Krista

    2007-01-01

    This educational project involves prospective science teachers in implementing a natural science course for nonscience majors. The model creates a space for nonscience majors to experience learner-centered teaching practices while giving prospective teachers an opportunity to apply their science and science education course knowledge and learning.…

  12. Emotionally Intense Science Activities

    NASA Astrophysics Data System (ADS)

    King, Donna; Ritchie, Stephen; Sandhu, Maryam; Henderson, Senka

    2015-08-01

    Science activities that evoke positive emotional responses make a difference to students' emotional experience of science. In this study, we explored 8th Grade students' discrete emotions expressed during science activities in a unit on Energy. Multiple data sources including classroom videos, interviews and emotion diaries completed at the end of each lesson were analysed to identify individual student's emotions. Results from two representative students are presented as case studies. Using a theoretical perspective drawn from theories of emotions founded in sociology, two assertions emerged. First, during the demonstration activity, students experienced the emotions of wonder and surprise; second, during a laboratory activity, students experienced the intense positive emotions of happiness/joy. Characteristics of these activities that contributed to students' positive experiences are highlighted. The study found that choosing activities that evoked strong positive emotional experiences, focused students' attention on the phenomenon they were learning, and the activities were recalled positively. Furthermore, such positive experiences may contribute to students' interest and engagement in science and longer term memorability. Finally, implications for science teachers and pre-service teacher education are suggested.

  13. The Scilink Project: Linking Science Classrooms for Cooperative Research.

    ERIC Educational Resources Information Center

    Morford, Gary

    1990-01-01

    Described is a pilot program designed to develop communication links between local science classrooms. The effects of the use of Sci-Link will be investigated. The proposed Sci-Link projects are described including stream acidity, raindrop size, rocket payloads, gypsy moth populations, and home energy use. (KR)

  14. Professional Networks in the Life Sciences: Linking the Linked

    PubMed Central

    Deisboeck, Thomas S.; Sagotsky, Jonathan

    2010-01-01

    The world wide web has furthered the emergence of a multitude of online expert communities. Continued progress on many of the remaining complex scientific questions requires a wide ranging expertise spectrum with access to a variety of distinct data types. Moving beyond peer-to-peer to community-to-community interaction is therefore one of the biggest challenges for global interdisciplinary Life Sciences research, including that of cancer. Cross-domain data query, access, and retrieval will be important innovation areas to enable and facilitate this interaction in the coming years. PMID:20838607

  15. Links and Distinctions among Citizenship, Science, and Citizen Science

    ERIC Educational Resources Information Center

    Cooper, Caren B.

    2012-01-01

    Mueller, Tippins, and Bryan (2012) presented a new conceptualization of citizen science that is meant to facilitate emerging trends in the democratization of science and science education to produce civically engaged students. I review some relevant trends in the field of citizen science, for clarity here referred to as public participation in…

  16. Making Links between Maths and Science

    ERIC Educational Resources Information Center

    Hiscock, Naomi

    2012-01-01

    For some children maths and science are exciting subjects that work side by side, one providing the opportunity to practise and hone skills and knowledge gained from the other. For other children the subjects are disjointed and seem to bear no relationship to each other. Science can provide a wonderful opportunity to practise a variety of math…

  17. Visual Links: Discovery in Art and Science.

    ERIC Educational Resources Information Center

    Dake, Dennis M.

    Some specific aspects of the process of discovery are explored as they are experienced in the visual arts and the physical sciences. Both fields use the same visual/brain processing system, and both disciplines share an imaginative and productive interest in the disciplined use of imagistic thinking. Many productive interactions between visual…

  18. Science Linking Pulmonary Veins and Atrial Fibrillation

    PubMed Central

    Mahida, Saagar; Sacher, Frederic; Derval, Nicolas; Berte, Benjamin; Yamashita, Seigo; Hooks, Darren; Denis, Arnaud; Amraoui, Sana; Hocini, Meleze; Haissaguerre, Michel; Jais, Pierre

    2015-01-01

    Over the past few decades, significant progress has been made in understanding the mechanistic basis of atrial fibrillation (AF). One of the most important discoveries in this context has been that pulmonary veins (PV) play a prominent role in the pathogenesis of AF. PV isolation has since become the most widely used technique for treatment of paroxysmal AF. Multiple studies have demonstrated that the electrophysiological and anatomical characteristics of PVs create a proarrhythmogenic substrate. The following review discusses the mechanistic links between PVs and AF. PMID:26835098

  19. Linked Data: what does it offer Earth Sciences?

    NASA Astrophysics Data System (ADS)

    Cox, Simon; Schade, Sven

    2010-05-01

    'Linked Data' is a current buzz-phrase promoting access to various forms of data on the internet. It starts from the two principles that have underpinned the architecture and scalability of the World Wide Web: 1. Universal Resource Identifiers - using the http protocol which is supported by the DNS system. 2. Hypertext - in which URIs of related resources are embedded within a document. Browsing is the key mode of interaction, with traversal of links between resources under control of the client. Linked Data also adds, or re-emphasizes: • Content negotiation - whereby the client uses http headers to tell the service what representation of a resource is acceptable, • Semantic Web principles - formal semantics for links, following the RDF data model and encoding, and • The 'mashup' effect - in which original and unexpected value may emerge from reuse of data, even if published in raw or unpolished form. Linked Data promotes typed links to all kinds of data, so is where the semantic web meets the 'deep web', i.e. resources which may be accessed using web protocols, but are in representations not indexed by search engines. Earth sciences are data rich, but with a strong legacy of specialized formats managed and processed by disconnected applications. However, most contemporary research problems require a cross-disciplinary approach, in which the heterogeneity resulting from that legacy is a significant challenge. In this context, Linked Data clearly has much to offer the earth sciences. But, there are some important questions to answer. What is a resource? Most earth science data is organized in arrays and databases. A subset useful for a particular study is usually identified by a parameterized query. The Linked Data paradigm emerged from the world of documents, and will often only resolve data-sets. It is impractical to create even nested navigation resources containing links to all potentially useful objects or subsets. From the viewpoint of human user

  20. A Thesaurus-Linked Science Question-Banking System.

    ERIC Educational Resources Information Center

    Johnson, Sandra; Maher, Brian

    1984-01-01

    Outlines implementation and uses of the computerized question-banking system of the thesaurus-linked browse procedure used by APU National Assessment in Science Programme. The ROOT Thesaurus, a comprehensive indexing and searching tool for technological applications, is described and its modifications are discussed as the basis for the…

  1. The Discourse of Design-Based Science Classroom Activities

    ERIC Educational Resources Information Center

    Azevedo, Flávio S.; Martalock, Peggy L.; Keser, Tugba

    2015-01-01

    This paper is an initial contribution to a general theory in which science classroom "activity types" and epistemological "discourse practices" are systematically linked. The idea is that activities and discourse are reflexively related, so that different types of science classroom activities (e.g., scientific argumentation,…

  2. Proceedings of the First International Linked Science Workshop

    SciTech Connect

    Pouchard, Line Catherine; Kauppinnen, Tomi; Kessler, Carsten

    2011-01-01

    Scientific efforts are traditionally published only as articles, with an estimate of millions of publications worldwide per year; the growth rate of PubMed alone is now 1 papers per minute. The validation of scientific results requires reproducible methods, which can only be achieved if the same data, processes, and algorithms as those used in the original experiments were available. However, the problem is that although publications, methods and datasets are very related, they are not always openly accessible and interlinked. Even where data is discoverable, accessible and assessable, significant challenges remain in the reuse of the data, in particular facilitating the necessary correlation, integration and synthesis of data across levels of theory, techniques and disciplines. In the LISC 2011 (1st International Workshop on Linked Science) we will discuss and present results of new ways of publishing, sharing, linking, and analyzing such scientific resources motivated by driving scientific requirements, as well as reasoning over the data to discover interesting new links and scientific insights. Making entities identifiable and referenceable using URIs augmented by semantic, scientifically relevant annotations greatly facilitates access and retrieval for data which used to be hardly accessible. This Linked Science approach, i.e., publishing, sharing and interlinking scientific resources and data, is of particular importance for scientific research, where sharing is crucial for facilitating reproducibility and collaboration within and across disciplines. This integrated process, however, has not been established yet. Bibliographic contents are still regarded as the main scientific product, and associated data, models and software are either not published at all, or published in separate places, often with no reference to the respective paper. In the workshop we will discuss whether and how new emerging technologies (Linked Data, and semantic technologies more

  3. An analysis of practice activities and instructional behaviours used by youth soccer coaches during practice: exploring the link between science and application.

    PubMed

    Ford, Paul R; Yates, Ian; Williams, A Mark

    2010-03-01

    We examined the practice activities and instructional behaviours employed by 25 youth soccer coaches during 70 different practice sessions. We evaluated the extent to which these activities and behaviours differ from those shown in contemporary research to best facilitate skill acquisition. Nine coaches worked with the under-9 years age group and eight coaches each with the under-13 and under-16 years age groups; nine of those coaches were employed at the elite level, nine at the sub-elite level, and seven at the non-elite level. Coaches had players spend more time in activities that were deemed less relevant to soccer match performance, termed "training form" (e.g. physical training, technique and skills practices), than activities deemed more relevant, termed "playing form" (e.g. small-sided/conditioned games and phase of play activities). Coaches provided high levels of instruction, feedback, and management, irrespective of the activity in which players engaged. Few differences in practice activities and instructional behaviours were reported across skill and age groups, implying the absence of any notable age- or skill-related progression. Findings are discussed with reference to recent research in the areas of skill acquisition, motor learning, and expert performance.

  4. World First MarsLink Mission Participants Learn and Enjoy Science

    ERIC Educational Resources Information Center

    Barry, Dana

    2005-01-01

    This article describes how students learn and experience the excitement of science by actively participating in the MarsLink Space Mission, an educational component of the National Aeronautics and Space Administration's (NASA) Mars Missions. This Mission has been made possible by Space Explorers, Inc., in collaboration with NASA. In the…

  5. Enabling Linked Science in Global Climate Uncertainty Quantification (UQ) Research

    NASA Astrophysics Data System (ADS)

    Elsethagen, T.; Stephan, E.; Lin, G.; Williams, D.; Banks, E.

    2012-12-01

    This paper shares a real-world global climate UQ science use case and illustrates how a linked science application called Provenance Environment (ProvEn), currently being developed, enables and facilitates scientific teams to publish, share, link, and discover new links over their UQ research results. UQ results include terascale datasets that are published to an Earth Systems Grid Federation (ESGF) repository. ProvEn demonstrates how a scientific team conducting UQ studies can discover dataset links using its domain knowledgebase, allowing them to better understand the UQ study research objectives, the experimental protocol used, the resulting dataset lineage, related analytical findings, ancillary literature citations, along with the social network of scientists associated with the study. This research claims that scientists using this linked science approach will not only allow them to greatly benefit from understanding a particular dataset within a knowledge context, a benefit can also be seen by the cross reference of knowledge among the numerous UQ studies being stored in ESGF. ProvEn collects native forms of data provenance resources as the UQ study is carried out. The native data provenance resources can be collected from a variety of sources such as scripts, a workflow engine log, simulation log files, scientific team members etc. Schema alignment is used to translate the native forms of provenance into a set of W3C PROV-O semantic statements used as a common interchange format which will also contain URI references back to resources in the UQ study dataset for querying and cross referencing. ProvEn leverages Fedora Commons' digital object model in a Resource Oriented Architecture (ROA) (i.e. a RESTful framework) to logically organize and partition native and translated provenance resources by UQ study. The ROA also provides scientists the means to both search native and translated forms of provenance.

  6. Science Activities in Energy: Conservation.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Presented is a science activities in energy package which includes 14 activities relating to energy conservation. Activities are simple, concrete experiments for fourth, fifth and sixth grades, which illustrate principles and problems relating to energy. Each activity is outlined on a simple card which is introduced by a question. A teacher's…

  7. Concept Mapping: Linking Spheres in Earth System Science

    NASA Astrophysics Data System (ADS)

    Czajkowski, K. P.; Hedley, M.

    2009-12-01

    The Earth System Science Education Alliance (ESSEA) distance learning courses focus teachers on linking spheres of the earth: atmosphere, hydrosphere, lithosphere and biosphere. The University of Toledo has offered the ESSEA middle school grade course using jigsaw pedagogy nine times since 2002. Traditionally, the ESSEA course has teachers link spheres in linear causal chains. This past year we used concept mapping as a way for the teachers and pre-service students in the class to organize their study of the events: melting of ice sheets, Mt. Pinatubo eruption, Hurricane Katrina and draining of the Great Black Swamp. Concept mapping is a good way to visualize linkages between events and spheres. The outcome was that teachers and pre-service students enjoyed concept mapping, it fostered teamwork and helped with grading the material.

  8. Modeling Activities in Earth Science

    NASA Astrophysics Data System (ADS)

    Malone, Kathy

    2014-05-01

    Students usually find science to be quite abstract. This is especially true of disciplines like Earth Science where it is difficult for the students to conduct and design hands-on experiments in areas such as Plate Tectonics that would allow them to develop predictive models. In the United States the new Next Generation Science Standards explicitly requires students to experience the science disciplines via modeling based activities. This poster presentation will discuss an activity that demonstrates how modeling, plate tectonics and student discourse converge in the earth science classroom. The activities featured on the poster will include using cardboard and shaving cream to demonstrate convergent plate boundaries, a Milky Way candy bar to demonstrate divergent boundaries and silly putty to demonstrate a strike slip boundary. I will discuss how students report back to the group about the findings from the lab and the techniques that can be used to heighten the student discourse. The activities outlined in this poster were originally designed for a middle school Earth Science class by Suzi Shoemaker for a graduate thesis at Arizona State University.

  9. Utah Science Activities, Update 2010

    USGS Publications Warehouse

    ,

    2010-01-01

    The U.S. Geological Survey (USGS), a bureau of the U.S. Department of the Interior, serves the Nation by providing reliable scientific information to describe and understand the Earth; minimize loss of life and property from natural disasters; manage water, biological, energy, and mineral resources; and enhance and protect our quality of life. The USGS has become a world leader in the natural sciences thanks to our scientific excellence and responsiveness to society's needs. This newsletter describes some of the current and recently completed USGS earth-science activities in Utah. As an unbiased, multi-disciplinary science organization that focuses on biology, geography, geology, and water, we are dedicated to the timely, relevant, and impartial study of the landscape, our natural resources, and the natural hazards that threaten us. Learn more about our goals and priorities for the coming decade in the USGS Science Strategy at http://www.usgs.gov/science_strategy/ .

  10. Open Science Grid: Linking Universities and Laboratories In National Cyberinfrastructure

    NASA Astrophysics Data System (ADS)

    Avery, Paul

    2011-10-01

    Open Science Grid is a consortium of researchers from universities and national laboratories that operates a national computing infrastructure serving large-scale scientific and engineering research. While OSG's scale has been primarily driven by the demands of the LHC experiments, it currently serves particle and nuclear physics, gravitational wave searches, digital astronomy, genomic science, weather forecasting, molecular modeling, structural biology and nanoscience. The OSG distributed computing facility links campus and regional computing resources and is a major component of the Worldwide LHC Computing Grid (WLCG) that handles the massive computing and storage needs of experiments at the Large Hadron Collider. This collaborative work has provided a wealth of results, including powerful new software tools and services; a uniform packaging scheme (the Virtual Data Toolkit) that simplifies software deployment across many sites in the US and Europe; integration of complex tools and services in large science applications; multiple education and outreach projects; and new approaches to integrating advanced network infrastructure in scientific computing applications. More importantly, OSG has provided unique collaborative opportunities between researchers in a variety of research disciplines.

  11. New Center Links Earth, Space, and Information Sciences

    NASA Astrophysics Data System (ADS)

    Aswathanarayana, U.

    2004-05-01

    Broad-based geoscience instruction melding the Earth, space, and information technology sciences has been identified as an effective way to take advantage of the new jobs created by technological innovations in natural resources management. Based on this paradigm, the University of Hyderabad in India is developing a Centre of Earth and Space Sciences that will be linked to the university's super-computing facility. The proposed center will provide the basic science underpinnings for the Earth, space, and information technology sciences; develop new methodologies for the utilization of natural resources such as water, soils, sediments, minerals, and biota; mitigate the adverse consequences of natural hazards; and design innovative ways of incorporating scientific information into the legislative and administrative processes. For these reasons, the ethos and the innovatively designed management structure of the center would be of particular relevance to the developing countries. India holds 17% of the world's human population, and 30% of its farm animals, but only about 2% of the planet's water resources. Water will hence constitute the core concern of the center, because ecologically sustainable, socially equitable, and economically viable management of water resources of the country holds the key to the quality of life (drinking water, sanitation, and health), food security, and industrial development of the country. The center will be focused on interdisciplinary basic and pure applied research that is relevant to the practical needs of India as a developing country. These include, for example, climate prediction, since India is heavily dependent on the monsoon system, and satellite remote sensing of soil moisture, since agriculture is still a principal source of livelihood in India. The center will perform research and development in areas such as data assimilation and validation, and identification of new sensors to be mounted on the Indian meteorological

  12. Marine Science Activities, Grade Two.

    ERIC Educational Resources Information Center

    Kolb, James A.

    This unit, one of a series designed to develop and foster an understanding of the marine environment, presents marine science activities for second grade students. The unit, focusing on awareness of living/non-living factors shaping life of the sea, is divided into sections dealing with: physical characteristics of oceans; fish; sea anemone;…

  13. Marine Science Activities, Grade Six.

    ERIC Educational Resources Information Center

    Kolb, James A.

    This unit, one of a series designed to develop and foster an understanding of the marine environment, presents marine science activities for grade 6 students. The unit is divided into the following sections: (1) Pagoo (story of a hermit crab); (2) introduction to marine environments; (3) salt water environment; (4) sea water investigations; (5)…

  14. Exploring Connections Between Earth Science and Biology - Interdisciplinary Science Activities for Schools

    NASA Astrophysics Data System (ADS)

    Vd Flier-Keller, E.; Carolsfeld, C.; Bullard, T.

    2009-05-01

    To increase teaching of Earth science in schools, and to reflect the interdisciplinary nature and interrelatedness of science disciplines in today's world, we are exploring opportunities for linking Earth science and Biology through engaging and innovative hands-on science activities for the classroom. Through the NSERC-funded Pacific CRYSTAL project based at the University of Victoria, scientists, science educators, and teachers at all levels in the school system are collaborating to research ways of enriching the preparation of students in math and science, and improving the quality of science education from Kindergarten to Grade 12. Our primary foci are building authentic, engaging science experiences for students, and fostering teacher leadership through teacher professional development and training. Interdisciplinary science activities represent an important way of making student science experiences real, engaging and relevant, and provide opportunities to highlight Earth science related topics within other disciplines, and to expand the Earth science taught in schools. The Earth science and Biology interdisciplinary project builds on results and experiences of existing Earth science education activities, and the Seaquaria project. We are developing curriculum-linked activities and resource materials, and hosting teacher workshops, around two initial areas; soils, and marine life and the fossil record. An example activity for the latter is the hands-on examination of organisms occupying the nearshore marine environment using a saltwater aquarium and touch tank or beach fieldtrip, and relating this to a suite of marine fossils to facilitate student thinking about representation of life in the fossil record e.g. which life forms are typically preserved, and how are they preserved? Literacy activities such as fossil obituaries encourage exploration of paleoenvironments and life habits of fossil organisms. Activities and resources are being tested with teachers

  15. Sciencing with Mother Goose: Activities for Integrating Science and Literature.

    ERIC Educational Resources Information Center

    Angus, Carolyn; Bell, Ann

    The pairing of Mother Goose rhymes and nursery tales with the scientific thinking process is an effective instructional strategy linking reading and science learning at the primary level. This paper presents several such pairings which stress the basic science processes in grades K-3 of observing, communicating, comparing, ordering, and…

  16. Linking Space Weather Science and Decision Making (Invited)

    NASA Astrophysics Data System (ADS)

    Fisher, G. M.

    2009-12-01

    Linking scientific knowledge to decision making is a challenge for both the science and policy communities. In particular, in the field of space weather, there are unique challenges such as decision makers may not know that space has weather that poses risks to our technologically-dependent economy. Additionally, in an era of limited funds for scientific research, hazards posed by other natural disasters such as flooding and earthquakes are by contrast well known to policy makers, further making the importance of space weather research and monitoring a tough sell. Today, with industries and individuals more dependent on the Global Positioning System, wireless technology, and satellites than ever before, any disruption or inaccuracy can result in severe economic impacts. Therefore, it is highly important to understand how space weather science can most benefit society. The key to connecting research to decision making is to ensure that the information is salient, credible, and legitimate. To achieve this, scientists need to understand the decision makers' perspectives, including their language and culture, and recognize that their needs may evolve. This presentation will take a closer look at the steps required to make space weather research, models, and forecasts useful to decision makers and ultimately, benefit society.

  17. Discovering Science through Art-Based Activities

    ERIC Educational Resources Information Center

    Alberts, Rebecca

    2010-01-01

    Art and science are intrinsically linked; the essence of art and science is discovery. Both artists and scientists work in a systematic but creative way--knowledge and understanding are built up through pieces of art or a series of labs. In the classroom, integrating science and visual art can provide students with the latitude to think, discover,…

  18. TeleScience Activities: Educational Uses of Electronic Networks.

    ERIC Educational Resources Information Center

    Waugh, Michael L.; Levin, James A.

    1989-01-01

    Described are successful science activities which have been conducted on an international telecommunications network which links schools in the United States, Mexico, Japan, and Israel. Examined are several activities currently being developed. Reports an innovative way to involve a wide range of students in the scientific process. (MVL)

  19. Linking Open Research Data for Earth and Space Science Informatics

    NASA Astrophysics Data System (ADS)

    Rozell, E.; Narock, T. W.

    2011-12-01

    Earth and Space Science Informatics (ESSI) is inherently multi-disciplinary, requiring close collaborations between scientists and information technologists. Identifying potential collaborations can be difficult, especially with the rapidly changing landscape of technologies and informatics projects. The ability to discover the technical competencies of other researchers in the community can help in the discovery of research partnerships. In addition to collaboration discovery, this data can be used to analyze trends in the field, which will help project managers identify emerging, irrelevant, and well-established technologies and specifications. This information will help keep projects focused on the technologies and standards that are actually being used, making them more useful to the ESSI community. We present a two-part solution to this problem: a pipeline for generating structured data from ESSI abstracts and an API and Web application for accessing the generated data. We use a Natural Language Processing (NLP) technique, Named Entity Disambiguation, to extract information about researchers, their affiliations, and technologies they have applied in their research. The extracted data is encoded in the Resource Description Framework using Linked Data vocabularies, including the Semantic Web for Research Communities ontology and the Friend-of-a-Friend ontology. The data is exposed in four ways: a SPARQL query-able endpoint, linked data, Java APIs, and a Web application. We also capture the provenance of the data transformations using the Proof Markup Language, including confidence scores from the NLP algorithms used. Our implementation has used only open source solutions, including DBPedia Spotlight and OpenNLP. We plan to set up an open source project for this work so that it can continue to evolve through community contributions.

  20. Linking Formal and Informal Science Education: A Successful Model using Libraries, Volunteers and NASA Resources

    NASA Astrophysics Data System (ADS)

    Race, M. S.; Lafayette Library; Learning Center Foundation (Lllcf)

    2011-12-01

    In these times of budget cuts, tight school schedules, and limited opportunities for student field trips and teacher professional development, it is especially difficult to expose elementary and middle school students to the latest STEM information-particularly in the space sciences. Using our library as a facilitator and catalyst, we built a volunteer-based, multi-faceted, curriculum-linked program for students and teachers in local middle schools (Grade 8) and showcased new astronomical and planetary science information using mainly NASA resources and volunteer effort. The project began with the idea of bringing free NASA photo exhibits (FETTU) to the Lafayette and Antioch Libraries for public display. Subsequently, the effort expanded by adding layers of activities that brought space and science information to teachers, students and the pubic at 5 libraries and schools in the 2 cities, one of which serves a diverse, underserved community. Overall, the effort (supported by a pilot grant from the Bechtel Foundation) included school and library based teacher workshops with resource materials; travelling space museum visits with hands-on activities (Chabot-to-Go); separate powerpoint presentations for students and adults at the library; and concurrent ancillary space-related themes for young children's programs at the library. This pilot project, based largely on the use of free government resources and online materials, demonstrated that volunteer-based, standards-linked STEM efforts can enhance curriculum at the middle school, with libraries serving a special role. Using this model, we subsequently also obtained a small NASA-Space Grant award to bring star parties and hand-on science activities to three libraries this Fall, linking with numerous Grade 5 teachers and students in two additional underserved areas of our county. It's not necessary to reinvent the wheel, you just collect the pieces and build on what you already have.

  1. Learning Activities Packages, Earth Science and Life Science.

    ERIC Educational Resources Information Center

    Miller Junior High School, Marshalltown, IA.

    Thirteen "Learning Activities Packages" for junior high school students focus on earth science and life science. Individual packages can be used with some lecture and films. Each learning activity package lists behavioral objectives and concepts to be used. Lists of reading assignments and references, along with laboratory activities, are also…

  2. Science priorities for seamounts: research links to conservation and management.

    PubMed

    Clark, Malcolm R; Schlacher, Thomas A; Rowden, Ashley A; Stocks, Karen I; Consalvey, Mireille

    2012-01-01

    Seamounts shape the topography of all ocean basins and can be hotspots of biological activity in the deep sea. The Census of Marine Life on Seamounts (CenSeam) was a field program that examined seamounts as part of the global Census of Marine Life (CoML) initiative from 2005 to 2010. CenSeam progressed seamount science by collating historical data, collecting new data, undertaking regional and global analyses of seamount biodiversity, mapping species and habitat distributions, challenging established paradigms of seamount ecology, developing new hypotheses, and documenting the impacts of human activities on seamounts. However, because of the large number of seamounts globally, much about the structure, function and connectivity of seamount ecosystems remains unexplored and unknown. Continual, and potentially increasing, threats to seamount resources from fishing and seabed mining are creating a pressing demand for research to inform conservation and management strategies. To meet this need, intensive science effort in the following areas will be needed: 1) Improved physical and biological data; of particular importance is information on seamount location, physical characteristics (e.g. habitat heterogeneity and complexity), more complete and intensive biodiversity inventories, and increased understanding of seamount connectivity and faunal dispersal; 2) New human impact data; these shall encompass better studies on the effects of human activities on seamount ecosystems, as well as monitoring long-term changes in seamount assemblages following impacts (e.g. recovery); 3) Global data repositories; there is a pressing need for more comprehensive fisheries catch and effort data, especially on the high seas, and compilation or maintenance of geological and biodiversity databases that underpin regional and global analyses; 4) Application of support tools in a data-poor environment; conservation and management will have to increasingly rely on predictive modelling

  3. Science Priorities for Seamounts: Research Links to Conservation and Management

    PubMed Central

    Clark, Malcolm R.; Schlacher, Thomas A.; Rowden, Ashley A.; Stocks, Karen I.; Consalvey, Mireille

    2012-01-01

    Seamounts shape the topography of all ocean basins and can be hotspots of biological activity in the deep sea. The Census of Marine Life on Seamounts (CenSeam) was a field program that examined seamounts as part of the global Census of Marine Life (CoML) initiative from 2005 to 2010. CenSeam progressed seamount science by collating historical data, collecting new data, undertaking regional and global analyses of seamount biodiversity, mapping species and habitat distributions, challenging established paradigms of seamount ecology, developing new hypotheses, and documenting the impacts of human activities on seamounts. However, because of the large number of seamounts globally, much about the structure, function and connectivity of seamount ecosystems remains unexplored and unknown. Continual, and potentially increasing, threats to seamount resources from fishing and seabed mining are creating a pressing demand for research to inform conservation and management strategies. To meet this need, intensive science effort in the following areas will be needed: 1) Improved physical and biological data; of particular importance is information on seamount location, physical characteristics (e.g. habitat heterogeneity and complexity), more complete and intensive biodiversity inventories, and increased understanding of seamount connectivity and faunal dispersal; 2) New human impact data; these shall encompass better studies on the effects of human activities on seamount ecosystems, as well as monitoring long-term changes in seamount assemblages following impacts (e.g. recovery); 3) Global data repositories; there is a pressing need for more comprehensive fisheries catch and effort data, especially on the high seas, and compilation or maintenance of geological and biodiversity databases that underpin regional and global analyses; 4) Application of support tools in a data-poor environment; conservation and management will have to increasingly rely on predictive modelling

  4. Science priorities for seamounts: research links to conservation and management.

    PubMed

    Clark, Malcolm R; Schlacher, Thomas A; Rowden, Ashley A; Stocks, Karen I; Consalvey, Mireille

    2012-01-01

    Seamounts shape the topography of all ocean basins and can be hotspots of biological activity in the deep sea. The Census of Marine Life on Seamounts (CenSeam) was a field program that examined seamounts as part of the global Census of Marine Life (CoML) initiative from 2005 to 2010. CenSeam progressed seamount science by collating historical data, collecting new data, undertaking regional and global analyses of seamount biodiversity, mapping species and habitat distributions, challenging established paradigms of seamount ecology, developing new hypotheses, and documenting the impacts of human activities on seamounts. However, because of the large number of seamounts globally, much about the structure, function and connectivity of seamount ecosystems remains unexplored and unknown. Continual, and potentially increasing, threats to seamount resources from fishing and seabed mining are creating a pressing demand for research to inform conservation and management strategies. To meet this need, intensive science effort in the following areas will be needed: 1) Improved physical and biological data; of particular importance is information on seamount location, physical characteristics (e.g. habitat heterogeneity and complexity), more complete and intensive biodiversity inventories, and increased understanding of seamount connectivity and faunal dispersal; 2) New human impact data; these shall encompass better studies on the effects of human activities on seamount ecosystems, as well as monitoring long-term changes in seamount assemblages following impacts (e.g. recovery); 3) Global data repositories; there is a pressing need for more comprehensive fisheries catch and effort data, especially on the high seas, and compilation or maintenance of geological and biodiversity databases that underpin regional and global analyses; 4) Application of support tools in a data-poor environment; conservation and management will have to increasingly rely on predictive modelling

  5. Science Teaching and Learning Activities and Students' Engagement in Science

    NASA Astrophysics Data System (ADS)

    Hampden-Thompson, Gillian; Bennett, Judith

    2013-06-01

    The purpose of this analysis is to describe the variation in students' reports of engagement in science across science teaching and learning activities. In addition, this study examines student and school characteristics that may be associated with students' levels of engagement in science. Data are drawn from the Programme for International Student Assessment 2006 study. The analysis employs a quantitative approach that includes descriptive and inferential statistics to examine three measures of student engagement for a nationally representative sample of approximately 12,000 15-year-old students in the UK. The main results indicate that there is an association between students' motivation towards science, enjoyment of science and future orientation towards science, and the frequency in which various teaching and learning activities take place in the classroom. Understanding student engagement in science and the factors that influence it is essential in addressing the issue of uptake of science after compulsory schooling.

  6. Nuclear Science Teaching Aids and Activities.

    ERIC Educational Resources Information Center

    Woodburn, John H.

    This publication is a sourcebook for science teachers. It provides guides for basic laboratory work in nuclear energy, suggesting various teacher and student demonstrations. Ideas for science clubs, science fairs, and project research seminars are presented. Problem-solving activities for both science and mathematics classes are included, as well…

  7. The Whole Cosmos. Catalog of Science Activities.

    ERIC Educational Resources Information Center

    Abruscato, Joe; Hassard, Jack

    Based on the notion that science begins and ends with the natural curiosity that young people have about themselves and the world, this book provides teachers and parents with many options for science exploration. Concepts are developed through science activities, creative arts activities, puzzles and games, and short biographies of individuals…

  8. A Linked Science Investigation: Enhancing Climate Change Data Discovery with Semantic Technologies

    PubMed Central

    Pouchard, Line C.; Branstetter, Marcia L.; Cook, Robert B.; Devarakonda, Ranjeet; Green, Jim; Palanisamy, Giri; Alexander, Paul; Noy, Natalya F.

    2013-01-01

    Linked Science is the practice of inter-connecting scientific assets by publishing, sharing and linking scientific data and processes in end-to-end loosely coupled workflows that allow the sharing and re-use of scientific data. Much of this data does not live in the cloud or on the Web, but rather in multi-institutional data centers that provide tools and add value through quality assurance, validation, curation, dissemination, and analysis of the data. In this paper, we make the case for the use of scientific scenarios in Linked Science. We propose a scenario in river-channel transport that requires biogeochemical experimental data and global climate-simulation model data from many sources. We focus on the use of ontologies—formal machine-readable descriptions of the domain—to facilitate search and discovery of this data. Mercury, developed at Oak Ridge National Laboratory, is a tool for distributed metadata harvesting, search and retrieval. Mercury currently provides uniform access to more than 100,000 metadata records; 30,000 scientists use it each month. We augmented search in Mercury with ontologies, such as the ontologies in the Semantic Web for Earth and Environmental Terminology (SWEET) collection by prototyping a component that provides access to the ontology terms from Mercury. We evaluate the coverage of SWEET for the ORNL Distributed Active Archive Center (ORNL DAAC). PMID:24416086

  9. A Linked Science Investigation: Enhancing Climate Change Data Discovery with Semantic Technologies.

    PubMed

    Pouchard, Line C; Branstetter, Marcia L; Cook, Robert B; Devarakonda, Ranjeet; Green, Jim; Palanisamy, Giri; Alexander, Paul; Noy, Natalya F

    2013-09-01

    Linked Science is the practice of inter-connecting scientific assets by publishing, sharing and linking scientific data and processes in end-to-end loosely coupled workflows that allow the sharing and re-use of scientific data. Much of this data does not live in the cloud or on the Web, but rather in multi-institutional data centers that provide tools and add value through quality assurance, validation, curation, dissemination, and analysis of the data. In this paper, we make the case for the use of scientific scenarios in Linked Science. We propose a scenario in river-channel transport that requires biogeochemical experimental data and global climate-simulation model data from many sources. We focus on the use of ontologies-formal machine-readable descriptions of the domain-to facilitate search and discovery of this data. Mercury, developed at Oak Ridge National Laboratory, is a tool for distributed metadata harvesting, search and retrieval. Mercury currently provides uniform access to more than 100,000 metadata records; 30,000 scientists use it each month. We augmented search in Mercury with ontologies, such as the ontologies in the Semantic Web for Earth and Environmental Terminology (SWEET) collection by prototyping a component that provides access to the ontology terms from Mercury. We evaluate the coverage of SWEET for the ORNL Distributed Active Archive Center (ORNL DAAC).

  10. Linking earth science informatics resources into uninterrupted digital value chains

    NASA Astrophysics Data System (ADS)

    Woodcock, Robert; Angreani, Rini; Cox, Simon; Fraser, Ryan; Golodoniuc, Pavel; Klump, Jens; Rankine, Terry; Robertson, Jess; Vote, Josh

    2015-04-01

    disparate data at much lower cost. An early example of this approach is the value generated by combining geological and metallurgical data sets as part of the rapidly growing field of geometallurgy. This not only provides a far better understanding of the impact of geological variability on ore processing but also leads to new thinking on the types and characteristics of data sets collected at various stages of the exploration and mining process. The Minerals Resources Flagship is linking its research activities to the AuScope infrastructure, exploiting the technology internally to create a platform for integrated research across the minerals value chain and improved interaction with industry. Referred to as the 'Early Access Virtual Lab', the system will be fully interoperable with AuScope and international infrastructures using open standards like GeosciML. Secured access is provided to allow confidential collaboration with industry when required. This presentation will discuss how the CSIRO Mineral Resources Flagship is building on the AuScope infrastructure to transform the way that data and data products are identified, shared, integrated, and reused, to unlock the benefits of true integration of research efforts across the minerals digital value chain.

  11. Linking Science Inquiry Skills in a Holistic Approach.

    ERIC Educational Resources Information Center

    Gabel, Connie

    The quest for the inclusion of science inquiry in the curriculum now spans three centuries. In the late 1800s and early 1900s, Armstrong, Dewey, and others espoused the teaching of science inquiry. The launch of Sputnik in 1957 began the strong emphasis on inquiry. Renewed interest in inquiry occurred in the late 1980s and 1990s with science…

  12. Activities for Science: Cooperative Learning Lessons (Challenging).

    ERIC Educational Resources Information Center

    Jasmine, Grace; Jasmine, Julia

    This book is designed to help advanced elementary students learn science skills while actively engaged in cooperative activities based on the earth sciences and natural disasters. The first section explains how to make cooperative learning a part of the curriculum and includes an overview, instructions and activities to bring cooperative learning…

  13. An Activities Handbook for Child Care: Science.

    ERIC Educational Resources Information Center

    Beasley, Georgia Blair, Comp.

    Designed for both the home economics teacher as a reference in planning a science unit in the child care curriculum, and for the student of child care as a resource for planning science activities, this handbook contains six units for teaching science to preschool children. Five of the units teach through imaginative finger plays and songs, and…

  14. Civic Engagement Assessment: Linking Activities to Attitudes

    ERIC Educational Resources Information Center

    Terkla, Dawn Geronimo; O'Leary, Lisa S.; Wilson, Nancy E.; Diaz, Ande

    2007-01-01

    Recently, higher education has witnessed a renewed commitment to the mission of preparing students for lives of active citizenship. Under the leadership of President Lawrence S. Bacow, Tufts University (Medford, Massachusetts) has articulated an institutional mission that embraces three areas of focus: active citizenship, internationalism, and…

  15. Molecular Science Computing Facility Scientific Challenges: Linking Across Scales

    SciTech Connect

    De Jong, Wibe A.; Windus, Theresa L.

    2005-07-01

    The purpose of this document is to define the evolving science drivers for performing environmental molecular research at the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) and to provide guidance associated with the next-generation high-performance computing center that must be developed at EMSL's Molecular Science Computing Facility (MSCF) in order to address this critical research. The MSCF is the pre-eminent computing facility?supported by the U.S. Department of Energy's (DOE's) Office of Biological and Environmental Research (BER)?tailored to provide the fastest time-to-solution for current computational challenges in chemistry and biology, as well as providing the means for broad research in the molecular and environmental sciences. The MSCF provides integral resources and expertise to emerging EMSL Scientific Grand Challenges and Collaborative Access Teams that are designed to leverage the multiple integrated research capabilities of EMSL, thereby creating a synergy between computation and experiment to address environmental molecular science challenges critical to DOE and the nation.

  16. Translating upwards: linking the neural and social sciences via neuroeconomics.

    PubMed

    Levallois, Clement; Clithero, John A; Wouters, Paul; Smidts, Ale; Huettel, Scott A

    2012-11-01

    The social and neural sciences share a common interest in understanding the mechanisms that underlie human behaviour. However, interactions between neuroscience and social science disciplines remain strikingly narrow and tenuous. We illustrate the scope and challenges for such interactions using the paradigmatic example of neuroeconomics. Using quantitative analyses of both its scientific literature and the social networks in its intellectual community, we show that neuroeconomics now reflects a true disciplinary integration, such that research topics and scientific communities with interdisciplinary span exert greater influence on the field. However, our analyses also reveal key structural and intellectual challenges in balancing the goals of neuroscience with those of the social sciences. To address these challenges, we offer a set of prescriptive recommendations for directing future research in neuroeconomics. PMID:23034481

  17. Coalition for Plasma Science (CPS) Education and Outreach Activities

    NASA Astrophysics Data System (ADS)

    Berry, L. A.

    2002-11-01

    The Coalition for Plasma Science (http://plasmacoalition.org/, CPS@plasmacoalition.org) is a group of institutions, organizations, and companies joining forces to increase awareness and understanding of plasma science and its many applications and benefits for society. Ongoing CPS educational activities include: (1) Construction and maintenance of a web site featuring "A Teacher's Guide to Plasma Science on the Web," a page that links to a wide range of plasma-related education sites, most of them analyzed for consistency with national science standards. The web site also directs visitors to our "Plasma Page," a brief, clear summary of plasma-related news; (2) Preparation of two-page articles on a wide range of plasma topics, including lighting, fusion, and space plasmas; and (3) Printing and distribution of an educational brochure entitled "Plasmas are Everywhere." The audience for these activities is primarily nontechnical, and includes students, teachers, and policy makers.

  18. Great Activities for Great Science Teaching.

    ERIC Educational Resources Information Center

    Weiner, Esther B.

    1993-01-01

    Presents hands-on spring science activities to help elementary students think and act like scientists. Students use the scientific process to make connections between life, physical, and earth science. Activities look at insects, flowers, trees, the sun, and the earth's rotation around the sun. (SM)

  19. Internet Links for Science Education: Student-Scientist Partnerships.

    ERIC Educational Resources Information Center

    Cohen, Karen C., Ed.

    This volume focuses on Student-Scientist Partnerships (SSPs) and illustrates the workings and effectiveness of this new paradigm and growing force in science education. The chapters are: chapter 1, "Student-Scientist Partnerships: Shrewd Maneuvers" (Robert F. Tinker); chapter 2, "The GLOBE Program: A Model for International Environmental…

  20. Nursing agency: the link between practical nursing science and nursing practice.

    PubMed

    Banfield, Barbara E

    2011-01-01

    The relationship of nursing science and nursing practice has been the topic of numerous discussions over the past decades. According to Orem, nursing science is a practical science, meaning that knowledge is developed for the sake of nursing practice. Within Orem's self-care deficit nursing theory, the concept of nursing agency links nursing science and nursing practice. Nursing agency refers to the power or ability of the nurse to design and produce systems of care. The relationship of practical nursing science, nursing practice, and nursing agency is examined in this article. Suggestions for further work related to nursing agency are provided.

  1. SCIENCE OF INTEGRATED WATERSHED MANAGEMENT: LINKING POLLUTANT CONTROL PRACTICES WITH WATER QUALITY

    EPA Science Inventory

    SCIENCE OF INTEGRATED WATERSHED MANAGEMENT: LINKING POLLUTANT CONTROL PRACTICES WITH WATER QUALITY M. Morrison (NRMRL), C. Nietch (NRMRL), 1. Schubauer-Berigan (NRMRL), M. Hantush (NRMRL), D. Lai (NRMRL), B. Daniel (NERL), M. Griffith (NCEA) Science Questions LTG 3. MYP Sc...

  2. Engaging Students in Authentic Science through School-Community Links: Learning from the Rural Experience

    ERIC Educational Resources Information Center

    Tytler, Russell; Symington, David; Kirkwood, Valda; Malcolm, Cliff

    2008-01-01

    There is an increase in school-community linked initiatives in school science. A substantial proportion of these involve rural schools. This article asks the question: In what ways do these initiatives offer possibilities for better engaging rural students with school science? The paper draws on information from a number of school-community linked…

  3. Prefrontal Activity Links Nonoverlapping Events in Memory

    PubMed Central

    Miyawaki, Hiroyuki; Helmstetter, Fred J.; Diba, Kamran

    2013-01-01

    The medial prefrontal cortex (mPFC) plays an important role in memory. By maintaining a working memory buffer, neurons in prelimbic (PL) mPFC may selectively contribute to learning associations between stimuli that are separated in time, as in trace fear conditioning (TFC). Until now, evidence for this bridging role was largely descriptive. Here we used optogenetics to silence neurons in the PL mPFC of rats during learning in TFC. Memory formation was prevented when mPFC was silenced specifically during the interval separating the cue and shock. Our results provide support for a working memory function for these cells and indicate that associating two noncontiguous stimuli requires bridging activity in PL mPFC. PMID:23804110

  4. Activity Sourcebook for Earth Science. Science Education Information Report.

    ERIC Educational Resources Information Center

    Mayer, Victor J., Ed.

    Designed to provide teachers of earth science with activities and information that will assist them in keeping their curricula up to date, this publication contains activities grouped into six chapters. Chapter titles are: (1) Weather and Climate, (2) Oceans, (3) The Earth and Its Surface, (4) Plate Tectonics, (5) Uses of Space Photography, and…

  5. Science Activities in Energy: Electrical Energy.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Presented is a science activities in energy package which includes 16 activities relating to electrical energy. Activities are simple, concrete experiments for fourth, fifth and sixth grades which illustrate principles and problems relating to energy. Each activity is outlined in a single card which is introduced by a question. A teacher's…

  6. Science Activities in Energy: Solar Energy.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Presented is a science activities in energy package which includes 12 activities relating to solar energy. Activities are simple, concrete experiments for fourth, fifth, and sixth grades, which illustrate principles and problems relating to energy. Each activity is outlined on a single card which is introduced by a question. A teacher's supplement…

  7. Science Activities in Energy: Chemical Energy.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Presented is a science activities in energy package which includes 15 activities relating to chemical energy. Activities are simple, concrete experiments for fourth, fifth and sixth grades which illustrate principles and problems relating to energy. Each activity is outlined on a single card which is introduced by a question. A teacher's…

  8. [Secondary Career Education Activities: Science.

    ERIC Educational Resources Information Center

    Radford City Schools, VA.

    The guide is one of a series developed in a pilot project to integrate career education concepts with subject matter in secondary grades. The units are designed to reveal career orientation aspects of traditional topics within five major subject areas: English, social studies, mathematics, science, and health and physical education. The lesson…

  9. Linking Science and Language Arts: A Review of the Literature Which Compares Integrated Versus Non-integrated Approaches

    NASA Astrophysics Data System (ADS)

    Bradbury, Leslie U.

    2014-06-01

    The purpose of this paper is to review the literature published during the last 20 years that investigates the impact of approaches that describe themselves as integrating science and language arts on student learning and/or attitude at the elementary level. The majority of papers report that integrated approaches led to greater student achievement in science and language arts across elementary grade levels. Additionally, integrated approaches facilitate improved attitudes toward both science and reading. The second section of the findings provides an overview of the types of pedagogical approaches used in the classrooms described in the studies. At all grade levels, teachers linked a variety of strategies including read-alouds, independent reading, at home reading, and writing in various genres that connected hands-on science activities to language arts skills.

  10. The discourse of design-based science classroom activities

    NASA Astrophysics Data System (ADS)

    Azevedo, Flávio S.; Martalock, Peggy L.; Keser, Tugba

    2015-06-01

    This paper is an initial contribution to a general theory in which science classroom activity types and epistemological discourse practices are systematically linked. The idea is that activities and discourse are reflexively related, so that different types of science classroom activities (e.g., scientific argumentation, modeling, and design) recruit characteristically distinct forms of participants' (students and teacher) discourse. Such a general theory would eventually map out the full spectrum of discourse practices (and their patterns of manifestation) across various kinds of science classroom activities, and reveal new relationships between forms of both discourse and activities. Because this defines a complex and long-term project, here our aim is simply to delineate this larger theoretical program and to illustrate it with a detailed case study—namely, that of mapping out and characterizing the discourse practices of design- based science classroom activities. To do so, we draw on data from an activity that is prototypically design-based—i.e., one in which students iteratively design and refine an artifact (in this case, pictorial representations of moving objects)—and examine the structure and dynamics of the whole-class discourse practices that emerge around these representational forms. We then compare and contrast these discourse practices to those of an activity that is prototypical of scientific argumentation (taken from the literature)—i.e., one in which students argue between competing theories and explanations of a phenomenon—and begin to illustrate the kinds of insights our theoretical program might afford.

  11. Solar Energy Project, Activities: Junior High Science.

    ERIC Educational Resources Information Center

    Tullock, Bruce, Ed.; And Others

    This guide contains lesson plans and outlines of science activities which present concepts of solar energy in the context of the junior high science curriculum. Each unit presents an introduction; objectives; skills and knowledge needed; materials; methods; questions; recommendations for further work; and a teacher information sheet. The teacher…

  12. Solar Energy Project, Activities: Earth Science.

    ERIC Educational Resources Information Center

    Tullock, Bruce, Ed.; And Others

    This guide contains lesson plans and outlines of science activities which present concepts of solar energy in the context of earth science experiments. Each unit presents an introduction; objectives; skills and knowledge needed; materials; method; questions; recommendations for further study; and a teacher information sheet. The teacher…

  13. Schoolyard Science: 101 Easy and Inexpensive Activities

    ERIC Educational Resources Information Center

    Lord, Thomas R.; Travis, Holly J.

    2011-01-01

    With 101 easy and inexpensive activities to do on school grounds, "Schoolyard Science" can help students develop their observation and inquiry skills as well as an appreciation of their outdoor environment. Covering topics such as lower plants, gardens, insects and other invertebrates, energy, and Earth science, Thomas Lord and Holly Travis…

  14. Literature Links: Thematic Units Linking Read-Alouds and Computer Activities

    ERIC Educational Resources Information Center

    Labbo, Linda D.; Love, Mary Susan; Park Prior, Miri; Hubbard, Betty P.; Ryan, Tammy

    2006-01-01

    This book gives the reader ideas for providing primary-grade students with literacy learning opportunities that integrate conventional literacies, such as phonics and comprehension, with new literacies, such as multimedia composition and hyperlink navigation. The reader will find a variety of linked activities, including reading children's books,…

  15. Synthesis and biological activity of new arenediyne-linked isoxazolidines.

    PubMed

    Romeo, Roberto; Navarra, Michele; Giofrè, Salvatore V; Carnovale, Caterina; Cirmi, Santa; Lanza, Giuseppe; Chiacchio, Maria A

    2014-07-01

    Arenediyne-isoxazolidine conjugates have been synthesized as a new scaffold for the development of bioactive mimics. Some of the synthesized compounds are endowed with antiproliferative activity against three human cancer cell lines. Their thermal reactivity suggests that the biological activity probably could not be linked to the Bergman cyclization.

  16. [Fernbank Science Center Environmental Activities].

    ERIC Educational Resources Information Center

    Shelton, Lewis

    This document is a compilation of environmental activities related directly to the environment in Georgia. A description of the physiographic characteristics of Georgia is presented upon which the activities that follow are based. These activities include soil, stream and forest investigations; meteorology activities; and plant and animal studies.…

  17. Science IDEAS: A Research-Based K-5 Interdisciplinary Instructional Model Linking Science and Literacy

    ERIC Educational Resources Information Center

    Romance, Nancy R.; Vitale, Michael R.

    2012-01-01

    Science IDEAS is an evidence-based model that reflects interdisciplinary research findings that support the integration of literacy (e.g., reading comprehension) within science instruction in grades K-5. Presented is a framework for planning integrated science and literacy instruction in which six elements (hands-on investigations, reading,…

  18. Linking Proportionality across the Science and Mathematics Curricula through Science Literacy Maps

    ERIC Educational Resources Information Center

    Richardson, Kerri; Matthews, Catherine; Thompson, Catherine

    2008-01-01

    Proportionality should be a central focus of the middle-grades science and mathematics curricula and concepts such as density can be introduced and taught in both disciplines, highlighting for students the connections between science and mathematics. This month's column describes how teachers can utilize the "The Atlas of Science Literacy" and…

  19. Linked Active Content: A Service for Digital Libraries for Education.

    ERIC Educational Resources Information Center

    Yaron, David; Milton, D. Jeff; Freeland, Rebecca

    A service is described to help enable digital libraries for education, such as the NSDL (National Science Mathematics Engineering and Technology Education Digital Library), to serve as collaboration spaces for the creation, modification and use of active learning experiences. The goal is to redefine the line between those activities that fall…

  20. Individualized Instruction in Science, Introductory Physical Science, Learning Activity Packages.

    ERIC Educational Resources Information Center

    Kuczma, R. M.

    Learning Activity Packages (LAP) mostly relating to the Introductory Physical Science Text are presented in this manual for use in sampling a new type of instruction. The total of 14 topics are incorporated into five units: (1) introduction to individualized learning; (2) observation versus interpretation; (3) quantity of matter; (4) introduction…

  1. Science Activities in Energy: Wind Energy.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Included in this science activities energy package are 12 activities related to wind energy for elementary students. Each activity is outlined on a single card and is introduced by a question. Topics include: (1) At what time of day is there enough wind to make electricity where you live?; (2) Where is the windiest spot on your schoolground?; and…

  2. INTEGRATED WATERSHED MANAGEMENT: LINKING SCIENCE TO DECISION MAKING

    EPA Science Inventory

    This paper describes some of the challenges and benefits of taking an integrated watershed approach to achieving Clean Water Act (CWA) and Safe Drinking Water Act (SDWA) goals, and some of the activities in EPA to facilitate watershed management decision making.

  3. Repeated games and direct reciprocity under active linking.

    PubMed

    Pacheco, Jorge M; Traulsen, Arne; Ohtsuki, Hisashi; Nowak, Martin A

    2008-02-21

    Direct reciprocity relies on repeated encounters between the same two individuals. Here we examine the evolution of cooperation under direct reciprocity in dynamically structured populations. Individuals occupy the vertices of a graph, undergoing repeated interactions with their partners via the edges of the graph. Unlike the traditional approach to evolutionary game theory, where individuals meet at random and have no control over the frequency or duration of interactions, we consider a model in which individuals differ in the rate at which they seek new interactions. Moreover, once a link between two individuals has formed, the productivity of this link is evaluated. Links can be broken off at different rates. Whenever the active dynamics of links is sufficiently fast, population structure leads to a simple transformation of the payoff matrix, effectively changing the game under consideration, and hence paving the way for reciprocators to dominate defectors. We derive analytical conditions for evolutionary stability.

  4. Links and Distinctions among Citizenship, Science, and Citizen Science. A Response to "The Future of Citizen Science"

    ERIC Educational Resources Information Center

    Cooper, Caren B.

    2012-01-01

    Mueller, Tippins, and Bryan (2012) presented a new conceptualization of citizen science that is meant to facilitate emerging trends in the democratization of science and science education to produce civically engaged students. I review some relevant trends in the field of citizen science, for clarity here referred to as public participation in…

  5. Everyday science & science every day: Science-related talk & activities across settings

    NASA Astrophysics Data System (ADS)

    Zimmerman, Heather

    To understand the development of science-related thinking, acting, and learning in middle childhood, I studied youth in schools, homes, and other neighborhood settings over a three-year period. The research goal was to analyze how multiple everyday experiences influence children's participation in science-related practices and their thinking about science and scientists. Ethnographic and interaction analysis methodologies were to study the cognition and social interactions of the children as they participated in activities with peers, family, and teachers (n=128). Interviews and participant self-documentation protocols elucidated the participants' understandings of science. An Everyday Expertise (Bell et al., 2006) theoretical framework was employed to study the development of science understandings on three analytical planes: individual learner, social groups, and societal/community resources. Findings came from a cross-case analysis of urban science learners and from two within-case analyses of girls' science-related practices as they transitioned from elementary to middle school. Results included: (1) children participated actively in science across settings---including in their homes as well as in schools, (2) children's interests in science were not always aligned to the school science content, pedagogy, or school structures for participation, yet children found ways to engage with science despite these differences through crafting multiple pathways into science, (3) urban parents were active supporters of STEM-related learning environments through brokering access to social and material resources, (4) the youth often found science in their daily activities that formal education did not make use of, and (5) children's involvement with science-related practices can be developed into design principles to reach youth in culturally relevant ways.

  6. Metadata Objects for Linking the Environmental Sciences (MOLES)

    NASA Astrophysics Data System (ADS)

    Lawrence, B.; Cox, S.; Ventouras, S.

    2009-04-01

    MOLES is an information model that provides a framework to support interdisciplinary contextual metadata describing instruments, observation platforms, activities, calibrations and other aspects of the environment associated with observations and simulations. MOLES has been designed as a bridge between discovery metadata - the conventional stuff of catalogues - and the sort of metadata which scientists traditionally store alongside data within files (and more rarely, databases) - "header files" and the like. MOLES can also be thought of as both a metadata structure in it's own right, and a framework for describing and recording the relationships between aspects of the context described in other more metadata formats (such as SensorML and the upcoming Metafor Common Information Model). MOLES was originally conceived of during the first NERC DataGrid project, in 2002, and is now at V3 in 2009. V3 differs from previous versions in many significant ways: 1) it has been designed in ISO 19103 compliant UML, and an XML schema implementation is delivered via an automated implementation of the ISO19118/19136 model driven architecture. 2) it is designed to operate in Web2.0 environment with both an atom serialisation and an OGC Web Feature Service (WFS) friendly XML serialisation. 3) it leverages the OGC observations and measurements specification, complements a range of GML application schema (in particular GeoSciML and CSML), and supports export of a subset of information in ISO 19115/19139 compliance. A software implementation exploiting MOLES V3 is under development. This will be seeded with hundreds of enties available from the MOLES V2 service currently deployed in the STFC Centre for Environmental Data Archival.

  7. Marine Science Activities for Visually Impaired.

    ERIC Educational Resources Information Center

    Schatz, Dennis; And Others

    These marine education materials are based on the approach that students learn best when given a multisensory experience. The activities are intended to develop such experiences for the visually impaired child. Activities are intended to supplement an upper-elementary science curriculum or be the basis of a unit on marine biology. The guide is…

  8. Stepping Stones to Science: True Tales and Awesome Activities.

    ERIC Educational Resources Information Center

    Haven, Kendall

    Science is filled with moments of long-sought understanding, and smaller moments of personal insight and victory. Thirteen such moments from physical, biological, and earth sciences appear in this book of stories. They each link well with the primary science curriculum. Each demonstrates the "doing" of science in which a preeminent scientist…

  9. Activity of Nagoya Science Literacy Forum

    NASA Astrophysics Data System (ADS)

    Yasuda, J.; Taniguchi, M.; Uchida, T.; Kawakatsu, H.

    2010-07-01

    Recently in Japan, there is growing interest in scientific literacy and education on it. In order to make various people to learn scientific literacy, we, the faculty members of the universities in Nagoya, established an organization, Nagoya Science Literacy Forum. We have hosted events as to scientific literacy and science experiments for students, faculty members, and the general public. In these events, we give them opportunities to learn scientific literacy and consider it with enjoying the science experiments. In this article, we show firstly an outline of education on scientific literacy in Japan, and then introduce our activities.

  10. Inquiry Science and Active Reading

    ERIC Educational Resources Information Center

    Sandifer, Cody

    2011-01-01

    Pairing an inquiry lesson with a traditional reading activity creates a jarring philosophical mismatch between the interaction, deep thinking, and scientific reasoning that drives meaningful inquiry instruction and the "scan the text, copy the answers" response often obtained from elementary nonfiction readers. Realizing that there must be a…

  11. Science Activities in Energy: Solar Energy II.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Included in this science activities energy package are 14 activities related to solar energy for secondary students. Each activity is outlined on a single card and is introduced by a question such as: (1) how much solar heat comes from the sun? or (2) how many times do you have to run water through a flat-plate collector to get a 10 degree rise in…

  12. 101 Environmental Education Activities. Booklet 4--Science Activities.

    ERIC Educational Resources Information Center

    Whitney, Helen, Comp.

    Fourth in the series "101 Environmental Education Activities" by the Upper Mississippi River ECO-Center, the booklet contains 39 environment-based science activities directed to students in primary, intermediate, and junior high classes. Organization of the activities usually includes grade level, objectives, procedures, and materials, evaluation…

  13. ESA Science Archives and associated VO activities

    NASA Astrophysics Data System (ADS)

    Arviset, Christophe; Baines, Deborah; Barbarisi, Isa; Castellanos, Javier; Cheek, Neil; Costa, Hugo; Fajersztejn, Nicolas; Gonzalez, Juan; Fernandez, Monica; Laruelo, Andrea; Leon, Ignacio; Ortiz, Inaki; Osuna, Pedro; Salgado, Jesus; Tapiador, Daniel

    ESA's European Space Astronomy Centre (ESAC), near Madrid, Spain, hosts most of ESA space based missions' scientific archives, in planetary (Mars Express, Venus Express, Rosetta, Huygens, Giotto, Smart-1, all in ESA Planetary Science Archive), in astronomy (XMM-Newton, Herschel, ISO, Integral, Exosat, Planck) and in solar physics (Soho). All these science archives are operated by a dedicated Science Archives and Virtual Observatory Team (SAT) at ESAC, enabling common and efficient design, development, operations and maintenance of the archives software systems. This also ensures long term preservation and availability of such science archives, as a sustainable service to the science community. ESA space science data can be accessed through powerful and user friendly user interface, as well as from machine scriptable interface and through VO interfaces. Virtual Observatory activities are also fully part of ESA archiving strategy and ESA is a very ac-tive partner in VO initiatives in Europe through Euro-VO AIDA and EuroPlanet and worldwide through the IVOA (International Virtual Observatory Alliance) and the IPDA (International Planetary Data Alliance).

  14. Space station freedom life sciences activities

    NASA Technical Reports Server (NTRS)

    Taylor, G. R.

    1994-01-01

    Life sciences activities being planned for Space Station Freedom (SSF) as of Fall 1992 are discussed. Planning for these activities is ongoing. Therefore, this description should be viewed as indicative of the prevailing ideas at one particular time in the SSF development cycle. The proposed contributions of the Canadian Space Agency (CSN) the European Space Agency (ESA), Japan, and the United States are all discussed in detail. In each case, the life sciences goals, and the way in which each partner proposes to achieve their goals, are reviewed.

  15. Linking science more closely to policy-making: Global climate change and the national reorganization of science and technology policy

    SciTech Connect

    Glasser, R.D.

    1994-04-01

    This paper examines the national trends behind recent efforts to link science and technology more closely to policy-making. It describes the politics surrounding the establishment of the National Science and Technology Council and its committee on Environment and Natural Resources (of which the global change program is a part). It discusses the evolution of the ``assessments`` function within the climate change program in general, and within the Department of Energy, in particular, and how the Clinton Administration`s approach to climate change ``assessments`` function within the climate change program in general, and within the Department of Energy, in particular, and how the Clinton Administration`s approach to climate change ``assessments`` differs from that of its predecessor. The paper concludes with a critique both of the national reorganization of science and technology policy and of the assessments component of the climate change program.

  16. Link Analysis of High Throughput Spacecraft Communication Systems for Future Science Missions

    NASA Technical Reports Server (NTRS)

    Simons, Rainee N.

    2015-01-01

    NASA's plan to launch several spacecrafts into low Earth Orbit (LEO) to support science missions in the next ten years and beyond requires down link throughput on the order of several terabits per day. The ability to handle such a large volume of data far exceeds the capabilities of current systems. This paper proposes two solutions, first, a high data rate link between the LEO spacecraft and ground via relay satellites in geostationary orbit (GEO). Second, a high data rate direct to ground link from LEO. Next, the paper presents results from computer simulations carried out for both types of links taking into consideration spacecraft transmitter frequency, EIRP, and waveform; elevation angle dependent path loss through Earths atmosphere, and ground station receiver GT.

  17. Link Analysis of High Throughput Spacecraft Communication Systems for Future Science Missions

    NASA Technical Reports Server (NTRS)

    Simons, Rainee N.

    2015-01-01

    NASA's plan to launch several spacecraft into low Earth Orbit (LEO) to support science missions in the next ten years and beyond requires down link throughput on the order of several terabits per day. The ability to handle such a large volume of data far exceeds the capabilities of current systems. This paper proposes two solutions, first, a high data rate link between the LEO spacecraft and ground via relay satellites in geostationary orbit (GEO). Second, a high data rate direct to ground link from LEO. Next, the paper presents results from computer simulations carried out for both types of links taking into consideration spacecraft transmitter frequency, EIRP, and waveform; elevation angle dependent path loss through Earths atmosphere, and ground station receiver GT.

  18. Optical link design and validation testing of the Optical Payload for Lasercomm Science (OPALS) system

    NASA Astrophysics Data System (ADS)

    Oaida, Bogdan V.; Wu, William; Erkmen, Baris I.; Biswas, Abhijit; Andrews, Kenneth S.; Kokorowski, Michael; Wilkerson, Marcus

    2014-03-01

    The Optical Payload for Lasercomm Science (OPALS) system developed by the Jet Propulsion Laboratory, California Institute of Technology, will be used for optical telecommunications link experiments from the International Space Station (ISS) to a ground telescope located at Table Mountain, CA. The launch of the flight terminal is scheduled for late February 2014 with an initially planned 90-day operations period following deployment on the exterior of the ISS. The simple, low-cost OPALS system will downlink a pre-encoded video file at 50 Mb/s on a 1550 nm laser carrier using on-off key (OOK) modulation and Reed-Solomon forward error correction. A continuous wave (cw) 976 nm multibeam laser beacon transmitted from the ground to the ISS will initiate link acquisition and tracking by the flight subsystem. Link analysis along with pre-flight results of the end-to-end free-space testing of the OPALS link are presented.

  19. Integrating Science and Policy: A Case Study of the Hubbard Brook Research Foundation Science Links Program

    ERIC Educational Resources Information Center

    Driscoll, Charles T.; Lambert, Kathy Fallon; Weathers, Kathleen C.

    2011-01-01

    Scientists, related professionals, and the public have for decades called for greater interaction among scientists, policymakers, and the media to address contemporary environmental challenges. Practical examples of effective "real-world" programs designed to catalyze interactions and provide relevant science are few. Existing successful models…

  20. 474 Science Activities for Young Children.

    ERIC Educational Resources Information Center

    Green, Moira D.

    This book uses a child-initiated, whole language approach to help children have fun while exploring the world of science. The activities are divided into 23 units. Each unit begins with an "Attention Getter," the purpose of which is to introduce the unit to children in a way that grabs their attention, stimulates their interest, and creates…

  1. Life and Environment. Elementary Science Activity Series.

    ERIC Educational Resources Information Center

    Blackwell, Frank F.

    This book, a volume of the High/Scope Elementary Curriculum science books series, is designed to bring the essential features of plant and animal environments into focus. It contains activities that enable students to gain insights into the life histories of animals and plants, their habitats, and their place in the broader picture of life on…

  2. MSLICE Science Activity Planner for the Mars Science Laboratory Mission

    NASA Technical Reports Server (NTRS)

    Powell, Mark W.; Shams, Khawaja S.; Wallick, Michael N.; Norris, Jeffrey S.; Joswig, Joseph C.; Crockett, Thomas M.; Fox, Jason M.; Torres, Recaredo J.; Kurien, James A.; McCurdy, Michael P.; Pyrzak, Guy; Aghevli, Arash; Bachmann, Andrew G.

    2009-01-01

    MSLICE (Mars Science Laboratory InterfaCE) is the tool used by scientists and engineers on the Mars Science Laboratory rover mission to visualize the data returned by the rover and collaboratively plan its activities. It enables users to efficiently and effectively search all mission data to find applicable products (e.g., images, targets, activity plans, sequences, etc.), view and plan the traverse of the rover in HiRISE (High Resolution Imaging Science Experiment) images, visualize data acquired by the rover, and develop, model, and validate the activities the rover will perform. MSLICE enables users to securely contribute to the mission s activity planning process from their home institutions using off-the-shelf laptop computers. This software has made use of several plug-ins (software components) developed for previous missions [e.g., Mars Exploration Rover (MER), Phoenix Mars Lander (PHX)] and other technology tasks. It has a simple, intuitive, and powerful search capability. For any given mission, there is a huge amount of data and associated metadata that is generated. To help users sort through this information, MSLICE s search interface is provided in a similar fashion as major Internet search engines. With regard to the HiRISE visualization of the rover s traverse, this view is a map of the mission that allows scientists to easily gauge where the rover has been and where it is likely to go. The map also provides the ability to correct or adjust the known position of the rover through the overlaying of images acquired from the rover on top of the HiRISE image. A user can then correct the rover s position by collocating the visible features in the overlays with the same features in the underlying HiRISE image. MSLICE users can also rapidly search all mission data for images that contain a point specified by the user in another image or panoramic mosaic. MSLICE allows the creation of targets, which provides a way for scientists to collaboratively name

  3. CHARMe Commentary metadata for Climate Science: collecting, linking and sharing user feedback on climate datasets

    NASA Astrophysics Data System (ADS)

    Blower, Jon; Lawrence, Bryan; Kershaw, Philip; Nagni, Maurizio

    2014-05-01

    The research process can be thought of as an iterative activity, initiated based on prior domain knowledge, as well on a number of external inputs, and producing a range of outputs including datasets, studies and peer reviewed publications. These outputs may describe the problem under study, the methodology used, the results obtained, etc. In any new publication, the author may cite or comment other papers or datasets in order to support their research hypothesis. However, as their work progresses, the researcher may draw from many other latent channels of information. These could include for example, a private conversation following a lecture or during a social dinner; an opinion expressed concerning some significant event such as an earthquake or for example a satellite failure. In addition, other sources of information of grey literature are important public such as informal papers such as the arxiv deposit, reports and studies. The climate science community is not an exception to this pattern; the CHARMe project, funded under the European FP7 framework, is developing an online system for collecting and sharing user feedback on climate datasets. This is to help users judge how suitable such climate data are for an intended application. The user feedback could be comments about assessments, citations, or provenance of the dataset, or other information such as descriptions of uncertainty or data quality. We define this as a distinct category of metadata called Commentary or C-metadata. We link C-metadata with target climate datasets using a Linked Data approach via the Open Annotation data model. In the context of Linked Data, C-metadata plays the role of a resource which, depending on its nature, may be accessed as simple text or as more structured content. The project is implementing a range of software tools to create, search or visualize C-metadata including a JavaScript plugin enabling this functionality to be integrated in situ with data provider portals

  4. Remarks on neurocybernetics and its links to computing science. To the memory of Prof. Luigi M. Ricciardi.

    PubMed

    Moreno-Díaz, Roberto; Moreno-Díaz, Arminda

    2013-06-01

    This paper explores the origins and content of neurocybernetics and its links to artificial intelligence, computer science and knowledge engineering. Starting with three remarkable pieces of work, we center attention on a number of events that initiated and developed basic topics that are still nowadays a matter of research and inquire, from goal directed activity theories to circular causality and to reverberations and learning. Within this context, we pay tribute to the memory of Prof. Ricciardi documenting the importance of his contributions in the mathematics of brain, neural nets and neurophysiological models, computational simulations and techniques.

  5. [Computer Science and Telecommunications Board activities

    SciTech Connect

    Blumenthal, M.S.

    1993-02-23

    The board considers technical and policy issues pertaining to computer science, telecommunications, and associated technologies. Functions include providing a base of expertise for these fields in NRC, monitoring and promoting health of these fields, initiating studies of these fields as critical resources and sources of national economic strength, responding to requests for advice, and fostering interaction among the technologies and the other pure and applied science and technology. This document describes its major accomplishments, current programs, other sponsored activities, cooperative ventures, and plans and prospects.

  6. Active link selection for efficient semi-supervised community detection.

    PubMed

    Yang, Liang; Jin, Di; Wang, Xiao; Cao, Xiaochun

    2015-01-01

    Several semi-supervised community detection algorithms have been proposed recently to improve the performance of traditional topology-based methods. However, most of them focus on how to integrate supervised information with topology information; few of them pay attention to which information is critical for performance improvement. This leads to large amounts of demand for supervised information, which is expensive or difficult to obtain in most fields. For this problem we propose an active link selection framework, that is we actively select the most uncertain and informative links for human labeling for the efficient utilization of the supervised information. We also disconnect the most likely inter-community edges to further improve the efficiency. Our main idea is that, by connecting uncertain nodes to their community hubs and disconnecting the inter-community edges, one can sharpen the block structure of adjacency matrix more efficiently than randomly labeling links as the existing methods did. Experiments on both synthetic and real networks demonstrate that our new approach significantly outperforms the existing methods in terms of the efficiency of using supervised information. It needs ~13% of the supervised information to achieve a performance similar to that of the original semi-supervised approaches. PMID:25761385

  7. Rockets: Physical science teacher's guide with activities

    NASA Technical Reports Server (NTRS)

    Vogt, Gregory L.; Rosenberg, Carla R. (Editor)

    1993-01-01

    This guide begins with background information sections on the history of rocketry, scientific principles, and practical rocketry. The sections on scientific principles and practical rocketry are based on Isaac Newton's three laws of motion. These laws explain why rockets work and how to make them more efficient. The background sections are followed with a series of physical science activities that demonstrate the basic science of rocketry. Each activity is designed to be simple and take advantage of inexpensive materials. Construction diagrams, materials and tools lists, and instructions are included. A brief discussion elaborates on the concepts covered in the activities and is followed with teaching notes and discussion questions. The guide concludes with a glossary of terms, suggested reading list, NASA educational resources, and an evaluation questionnaire with a mailer.

  8. Inflammation, Cancer and Oxidative Lipoxygenase Activity are Intimately Linked

    PubMed Central

    Wisastra, Rosalina; Dekker, Frank J.

    2014-01-01

    Cancer and inflammation are intimately linked due to specific oxidative processes in the tumor microenvironment. Lipoxygenases are a versatile class of oxidative enzymes involved in arachidonic acid metabolism. An increasing number of arachidonic acid metabolites is being discovered and apart from their classically recognized pro-inflammatory effects, anti-inflammatory effects are also being described in recent years. Interestingly, these lipid mediators are involved in activation of pro-inflammatory signal transduction pathways such as the nuclear factor κB (NF-κB) pathway, which illustrates the intimate link between lipid signaling and transcription factor activation. The identification of the role of arachidonic acid metabolites in several inflammatory diseases led to a significant drug discovery effort around arachidonic acid metabolizing enzymes. However, to date success in this area has been limited. This might be attributed to the lack of selectivity of the developed inhibitors and to a lack of detailed understanding of the functional roles of arachidonic acid metabolites in inflammatory responses and cancer. This calls for a more detailed investigation of the activity of arachidonic acid metabolizing enzymes and development of more selective inhibitors. PMID:25037020

  9. Examining the Link Between Public Transit Use and Active Commuting

    PubMed Central

    Bopp, Melissa; Gayah, Vikash V.; Campbell, Matthew E.

    2015-01-01

    Background: An established relationship exists between public transportation (PT) use and physical activity. However, there is limited literature that examines the link between PT use and active commuting (AC) behavior. This study examines this link to determine if PT users commute more by active modes. Methods: A volunteer, convenience sample of adults (n = 748) completed an online survey about AC/PT patterns, demographic, psychosocial, community and environmental factors. t-test compared differences between PT riders and non-PT riders. Binary logistic regression analyses examined the effect of multiple factors on AC and a full logistic regression model was conducted to examine AC. Results: Non-PT riders (n = 596) reported less AC than PT riders. There were several significant relationships with AC for demographic, interpersonal, worksite, community and environmental factors when considering PT use. The logistic multivariate analysis for included age, number of children and perceived distance to work as negative predictors and PT use, feelings of bad weather and lack of on-street bike lanes as a barrier to AC, perceived behavioral control and spouse AC were positive predictors. Conclusions: This study revealed the complex relationship between AC and PT use. Further research should investigate how AC and public transit use are related. PMID:25898405

  10. Mission and science activity scheduling language

    NASA Technical Reports Server (NTRS)

    Hull, Larry G.

    1993-01-01

    To support the distributed and complex operational scheduling required for future National Aeronautics and Space Administration (NASA) missions, a formal, textual language, the Scheduling Applications Interface Language (SAIL), has been developed. Increased geographic dispersion of investigators is leading to distributed mission and science activity planning, scheduling, and operations. SAIL is an innovation which supports the effective and efficient communication of scheduling information among physically dispersed applications in distributed scheduling environments. SAIL offers a clear, concise, unambiguous expression of scheduling information in a readable, hardware independent format. The language concept, syntax, and semantics incorporate language features found useful during five years of research and prototyping with scheduling languages in physically distributed environments. SAIL allows concise specification of mission and science activity plans in a format which promotes repetition and reuse.

  11. Linking geomagnetic activity and polar surface air temperature variability

    NASA Astrophysics Data System (ADS)

    Seppala, Annika

    ERA-40 and ECMWF operational surface level air temperature (SAT) data sets from 1957 to 2006 were used to examine polar temperature variations during years with different levels of geomagnetic activity, as defined by the Ap index. Previous modelling work has suggested that NOx produced at high latitudes by energetic particle precipitation can eventually lead to detectable changes in polar SATs. We find that during winter months, ERA-40 and ECMWF polar SATs in years with high Ap index are different than in years with low Ap index; the differences are statistically significant at the 2-sigma level and range up to about ±4.5 K, de-pending on location. The temperature differences are larger when years with wintertime Sudden Stratospheric Warmings are excluded. Solar irradiance variations were taken into account in the analysis. Although using the re-analysis and operational data sets it was not possible to conclusively show that the polar SAT patterns are physically linked by geomagnetic activity, we conclude that geomagnetic activity likely plays a role in modulating polar wintertime surface air temperature patterns. The SAT results were tested against variation in the Quasi Biennial Oscillation (QBO), the El Niño Southern Oscillation (ENSO) and the Southern Annular Mode n (SAM). The results suggested that these were not driving the observed polar SAT variability. However, significant uncertainty is introduced by the Northern Annular Mode (NAM) and we could not robustly exclude a chance linkage between sea surface temperature (SST) variability and geomagnetic activity. Examining the physical link between geomagnetic activity and polar surface temperature variability patterns using atmospheric models is an ongoing task.

  12. Science Learning: A path analysis of its links with reading comprehension, question-asking in class and science achievement

    NASA Astrophysics Data System (ADS)

    Cano, Francisco; García, Ángela; Berbén, A. B. G.; Justicia, Fernando

    2014-07-01

    The purpose of this research was to build and test a conceptual model of the complex interrelationships between students' learning in science (learning approaches and self-regulation), their reading comprehension, question-asking in class and science achievement. These variables were measured by means of a test and a series of questionnaires administered to 604 ninth-grade students, and the data collected were analysed using a correlational, cross-sectional design. Results of a path analysis indicated that (a) students' self-regulated and intentional knowledge-constructing activity (self-regulated strategy use, deep approach and knowledge-building) were what chiefly accounted for their question-asking in class; (b) question-asking (high and low levels) was related directly to reading comprehension and indirectly, through its contribution to the this, to academic achievement; (c) reading comprehension was directly and negatively associated with surface approach and indirectly and positively related to deep approach and knowledge-building; and (d) some of these variables, particularly reading comprehension, accounted for academic achievement in science. This model explained nearly 30% of the variance in academic achievement and provided a substantial and distinctive insight into the web of interrelationships among these variables. Implications for future research and science teaching and learning are discussed (e.g. the importance of supporting students' efforts to learn science in a meaningful, active and self-regulated way and of improving their reading comprehension).

  13. Tools to investigate how interprofessional education activities link to competencies.

    PubMed

    West, Courtney; Veronin, Michael; Landry, Karen; Kurz, Terri; Watzak, Bree; Quiram, Barbara; Graham, Lori

    2015-01-01

    Integrating interprofessional education (IPE) activities and curricular components in health professions education has been emphasized recently by the inclusion of accreditation standards across disciplines. The Interprofessional Education Collaborative (IPEC) established IPE competencies in 2009, but evaluating how activities link to competencies has not been investigated in depth. The purpose of this project is to investigate how well two IPE activities align with IPEC competencies. To evaluate how our IPE activities met IPEC competencies, we developed a checklist and an observation instrument. A brief description of each is included as well as the outcomes. We analyzed Disaster Day, a simulation exercise that includes participants from Nursing, Medicine, and Pharmacy, and Interprofessional Healthcare Ethics (IPHCE), a course that introduced medical, nursing, and pharmacy students to ethical issues using didactic sessions and case discussions. While both activities appeared to facilitate the development of IPE competencies, Disaster Day aligned more with IPEC competencies than the IPHCE course and appears to be a more comprehensive way of addressing IPEC competencies. However, offering one IPE activity or curricular element is not sufficient. Having several IPE options available, utilizing the tools we developed to map the IPE curriculum and evaluating competency coverage is recommended.

  14. Cellular Links between Neuronal Activity and Energy Homeostasis

    PubMed Central

    Shetty, Pavan K.; Galeffi, Francesca; Turner, Dennis A.

    2012-01-01

    Neuronal activity, astrocytic responses to this activity, and energy homeostasis are linked together during baseline, conscious conditions, and short-term rapid activation (as occurs with sensory or motor function). Nervous system energy homeostasis also varies during long-term physiological conditions (i.e., development and aging) and with adaptation to pathological conditions, such as ischemia or low glucose. Neuronal activation requires increased metabolism (i.e., ATP generation) which leads initially to substrate depletion, induction of a variety of signals for enhanced astrocytic function, and increased local blood flow and substrate delivery. Energy generation (particularly in mitochondria) and use during ATP hydrolysis also lead to considerable heat generation. The local increases in blood flow noted following neuronal activation can both enhance local substrate delivery but also provides a heat sink to help cool the brain and removal of waste by-products. In this review we highlight the interactions between short-term neuronal activity and energy metabolism with an emphasis on signals and factors regulating astrocyte function and substrate supply. PMID:22470340

  15. NASA'S Earth Science Data Stewardship Activities

    NASA Technical Reports Server (NTRS)

    Lowe, Dawn R.; Murphy, Kevin J.; Ramapriyan, Hampapuram

    2015-01-01

    NASA has been collecting Earth observation data for over 50 years using instruments on board satellites, aircraft and ground-based systems. With the inception of the Earth Observing System (EOS) Program in 1990, NASA established the Earth Science Data and Information System (ESDIS) Project and initiated development of the Earth Observing System Data and Information System (EOSDIS). A set of Distributed Active Archive Centers (DAACs) was established at locations based on science discipline expertise. Today, EOSDIS consists of 12 DAACs and 12 Science Investigator-led Processing Systems (SIPS), processing data from the EOS missions, as well as the Suomi National Polar Orbiting Partnership mission, and other satellite and airborne missions. The DAACs archive and distribute the vast majority of data from NASA’s Earth science missions, with data holdings exceeding 12 petabytes The data held by EOSDIS are available to all users consistent with NASA’s free and open data policy, which has been in effect since 1990. The EOSDIS archives consist of raw instrument data counts (level 0 data), as well as higher level standard products (e.g., geophysical parameters, products mapped to standard spatio-temporal grids, results of Earth system models using multi-instrument observations, and long time series of Earth System Data Records resulting from multiple satellite observations of a given type of phenomenon). EOSDIS data stewardship responsibilities include ensuring that the data and information content are reliable, of high quality, easily accessible, and usable for as long as they are considered to be of value.

  16. Physical Activity and Snus: Is There a Link?

    PubMed Central

    Henninger, Stéphane; Fischer, Roland; Cornuz, Jacques; Studer, Joseph; Gmel, Gerhard

    2015-01-01

    The study aimed at assessing the link between physical activity (PA), sports activity and snus use among young men in Switzerland. Data from the Cohort Study on Substance Use Risk Factors (C-SURF) were used to measure PA with the International Physical Activity Questionnaire and sports activity with a single item. Multivariate logistic regression analysis was conducted to measure the association between snus use, PA and sports activity. Similar models were run for smoking and snuff use. Snus use increased in a dose-response association with PA (high level: OR = 1.72; 95% CI 1.16–2.55) and with individuals exercising once a week or more often (OR = 1.65; 95% CI 1.26–2.16; p < 0.001) or almost every day (OR = 2.27; 95% CI 1.72–3.01; p < 0.001) in separate models. Entered simultaneously, only sports and exercise maintained a basically unchanged significant dose-response relationship, whereas PA became non-significant. A non-significant dose-response relation was found for cigarette smoking and snuff use, indicating that the association with sport is specific to snus and not to tobacco use in general or smokeless tobacco in particular. This study showed that the association between snus use and sports is not specific to Nordic countries. PMID:26121189

  17. Physical Activity and Snus: Is There a Link?

    PubMed

    Henninger, Stéphane; Fischer, Roland; Cornuz, Jacques; Studer, Joseph; Gmel, Gerhard

    2015-06-25

    The study aimed at assessing the link between physical activity (PA), sports activity and snus use among young men in Switzerland. Data from the Cohort Study on Substance Use Risk Factors (C-SURF) were used to measure PA with the International Physical Activity Questionnaire and sports activity with a single item. Multivariate logistic regression analysis was conducted to measure the association between snus use, PA and sports activity. Similar models were run for smoking and snuff use. Snus use increased in a dose-response association with PA (high level: OR = 1.72; 95% CI 1.16-2.55) and with individuals exercising once a week or more often (OR = 1.65; 95% CI 1.26-2.16; p < 0.001) or almost every day (OR = 2.27; 95% CI 1.72-3.01; p < 0.001) in separate models. Entered simultaneously, only sports and exercise maintained a basically unchanged significant dose-response relationship, whereas PA became non-significant. A non-significant dose-response relation was found for cigarette smoking and snuff use, indicating that the association with sport is specific to snus and not to tobacco use in general or smokeless tobacco in particular. This study showed that the association between snus use and sports is not specific to Nordic countries.

  18. Jupiter Atmospheric Science with JIMO: Linking Science Objectives and Measurement Goals

    NASA Technical Reports Server (NTRS)

    Chanover, N. J.; Glenar, D. A.; Simon-Miller, A. A.

    2003-01-01

    Although the primary focus of the Jupiter Icy Moons Orbiter (JIMO) mission will be the characterization and study of Jupiter's icy moons, there will be opportunities throughout the mission for unprecendented observations of Jupiter. With an adaptable suite of payload instruments, the atmospheric data collected by JIMO can help to answer fundamental questions about the largest planet in our solar system that remain after (or were generated by) previous spacecraft reconnaissance (e.g. Voyager, Galileo, and Cassini). Near-IR (0.7-4 micron) spectral imaging will most likely be used to identify mineralogies and ices on the Jovian satellites by virtue of their spectral signatures. This same capability is very well tailored for studies of Jovian atmospheric dynamics and structure. Near-IR methane absorption bands allow 2-D mapping of the horizontal wind field at size scales to tens of kms, as well as the height dependence of this field above the ammonia cloud deck (700 to a few mbar), constraining current models of atmospheric vertical structure. Likewise, atmospheric ice aerosols with unique spectroscopic signatures (ammonia ice near 1.5, 2.0, and 2.8 microns and water ice between 3.0 - 3.5 microns) can be detected and mapped using spectral difference imaging or spectrally inclusive principal-component methods. Spectral imaging of the Jovian aurora via (3)H(+) emission lines between 3 - 4 microns can be used to spatially map the interplay between the satellites) Jupiter's magnetosphere, and Jupiter's atmosphere. Each of these measurements addresses one or more fundamental questions related to the energy balance in Jupiter's atmosphere. All of these tunable imaging objectives can be achieved using acousto-optic tunable filters (AOTF's), which have been used for years in ground-based observing instruments and which have been proposed for numerous planetary missions. The application of this technology to the science objectives of both the icy satellites and Jovian

  19. "Active Science": Integrating Physical Activity and Science Learning into the Afterschool Environment

    ERIC Educational Resources Information Center

    Finn, Kevin E.; Yan, Zi; McInnis, Kyle J.

    2015-01-01

    Background: Afterschool programs offer significant opportunities to increase physical activity levels and improve academic performance of children. Purpose: This study assessed an innovative approach to embed physical activity into science lessons in an afterschool community setting. Methods: Participants were 47 boys and girls (age = 10.8 ± 0.7…

  20. Stabilized Photonic Links for Deep Space Tracking, Navigation, and Radio Science Applications

    NASA Technical Reports Server (NTRS)

    Huang, S.; Tjoelker, R. L.

    2012-01-01

    Stable fiber optic links have been operational in NASA's DSN for over 20 years providing distribution limited fractional frequency stability below 10-14 at one second and reaching 10-18 at approx 10,000 seconds. We summarize recent stabilized photonic link developments for DSN operation capable of high performance and reliability, and at much lower cost than previous systems. Recent research has focused on two applications, 1) actively stabilized links to transport 100 MHz metrology frequency references to sites up to 30 km from the central atomic frequency standard, and 2) stabilized links transporting broadband S, X, and Ka band signals used in deep space tracking and navigation and antenna arraying applications.

  1. Math and science motivation: A longitudinal examination of the links between choices and beliefs.

    PubMed

    Simpkins, Sandra D; Davis-Kean, Pamela E; Eccles, Jacquelynne S

    2006-01-01

    This study addresses the longitudinal associations between youths' out-of-school activities, expectancies-values, and high school course enrollment in the domains of math and science. Data were collected on 227 youth who reported on their activity participation in 5th grade, expectancies-values in 6th and 10th grade, and courses taken throughout high school. Math and science course grades at 5th and 10th grade were gathered through school record data. Results indicated youths' math and science activity participation predicted their expectancies and values, which, in turn, predicted the number of high school courses above the predictive power of grades. Although there were mean-level differences between boys and girls on some of these indicators, relations among indicators did not significantly differ by gender.

  2. Science Activities for Children 3 to 9 Years Old.

    ERIC Educational Resources Information Center

    Nelson, Bonnie E.

    Activities in the life and physical sciences are provided (in separate sections) for preschool and elementary school students. Life science activities include those related to plants, soil, habitats, fossils, animals, life cycles, food chains, nutrition, and other biologically-oriented topics. Physical science activities include those related to…

  3. Neuroligin-1 links neuronal activity to sleep-wake regulation

    PubMed Central

    El Helou, Janine; Bélanger-Nelson, Erika; Freyburger, Marlène; Dorsaz, Stéphane; Curie, Thomas; La Spada, Francesco; Gaudreault, Pierre-Olivier; Beaumont, Éric; Pouliot, Philippe; Lesage, Frédéric; Frank, Marcos G.; Franken, Paul; Mongrain, Valérie

    2013-01-01

    Maintaining wakefulness is associated with a progressive increase in the need for sleep. This phenomenon has been linked to changes in synaptic function. The synaptic adhesion molecule Neuroligin-1 (NLG1) controls the activity and synaptic localization of N-methyl-d-aspartate receptors, which activity is impaired by prolonged wakefulness. We here highlight that this pathway may underlie both the adverse effects of sleep loss on cognition and the subsequent changes in cortical synchrony. We found that the expression of specific Nlg1 transcript variants is changed by sleep deprivation in three mouse strains. These observations were associated with strain-specific changes in synaptic NLG1 protein content. Importantly, we showed that Nlg1 knockout mice are not able to sustain wakefulness and spend more time in nonrapid eye movement sleep than wild-type mice. These changes occurred with modifications in waking quality as exemplified by low theta/alpha activity during wakefulness and poor preference for social novelty, as well as altered delta synchrony during sleep. Finally, we identified a transcriptional pathway that could underlie the sleep/wake-dependent changes in Nlg1 expression and that involves clock transcription factors. We thus suggest that NLG1 is an element that contributes to the coupling of neuronal activity to sleep/wake regulation. PMID:23716671

  4. Effects of Node-Link Mapping on Non-Science Majors' Meaningful Learning and Conceptual Change in a Life-Science Survey Lecture Course

    ERIC Educational Resources Information Center

    Park-Martinez, Jayne Irene

    2011-01-01

    The purpose of this study was to assess the effects of node-link mapping on students' meaningful learning and conceptual change in a 1-semester introductory life-science course. This study used node-link mapping to integrate and apply the National Research Council's (NRC, 2005) three principles of human learning: engaging students' prior…

  5. Catawba Science Center solar activities. Final report

    SciTech Connect

    1983-01-01

    Two demonstration solar water heaters were built. One was to be used at the Science Center and the other with traveling programs. This was completed and both units are being used for these programs which continue. We were able to build a library of 99 solar energy books and booklets that are available to the public for reference. We also conducted programs for 683 students of all ages. The culminating activity was the planned Energy Awareness Festival. This was held on September 26, 1981 and attracted 450 area citizens. We offered free exhibit space and hosted 17 exhibitors.

  6. Linking Europa's plume activity to tides, tectonics, and liquid water

    NASA Astrophysics Data System (ADS)

    Rhoden, Alyssa Rose; Hurford, Terry A.; Roth, Lorenz; Retherford, Kurt

    2015-06-01

    Much of the geologic activity preserved on Europa's icy surface has been attributed to tidal deformation, mainly due to Europa's eccentric orbit. Although the surface is geologically young (30-80 Myr), there is little information as to whether tidally-driven surface processes are ongoing. However, a recent detection of water vapor near Europa's south pole suggests that it may be geologically active. Initial observations indicated that Europa's plume eruptions are time-variable and may be linked to its tidal cycle. Saturn's moon, Enceladus, which shares many similar traits with Europa, displays tidally-modulated plume eruptions, which bolstered this interpretation. However, additional observations of Europa at the same time in its orbit failed to yield a plume detection, casting doubt on the tidal control hypothesis. The purpose of this study is to analyze the timing of plume eruptions within the context of Europa's tidal cycle to determine whether such a link exists and examine the inferred similarities and differences between plume activity on Europa and Enceladus. To do this, we determine the locations and orientations of hypothetical tidally-driven fractures that best match the temporal variability of the plumes observed at Europa. Specifically, we identify model faults that are in tension at the time in Europa's orbit when a plume was detected and in compression at times when the plume was not detected. We find that tidal stress driven solely by eccentricity is incompatible with the observations unless additional mechanisms are controlling the eruption timing or restricting the longevity of the plumes. The addition of obliquity tides, and corresponding precession of the spin pole, can generate a number of model faults that are consistent with the pattern of plume detections. The locations and orientations of these hypothetical source fractures are robust across a broad range of precession rates and spin pole directions. Analysis of the stress variations across

  7. Edible Earth and Space Science Activities

    NASA Astrophysics Data System (ADS)

    Lubowich, D.; Shupla, C.

    2014-07-01

    In this workshop we describe using Earth and Space Science demonstrations with edible ingredients to increase student interest. We show how to use chocolate, candy, cookies, popcorn, bagels, pastries, Pringles, marshmallows, whipped cream, and Starburst candy for activities such as: plate tectonics, the interior structure of the Earth and Mars, radioactivity/radioactive dating of rocks and stars, formation of the planets, lunar phases, convection, comets, black holes, curvature of space, dark energy, and the expansion of the Universe. In addition to creating an experience that will help students remember specific concepts, edible activities can be used as a formative assessment, providing students with the opportunity to create something that demonstrates their understanding of the model. The students often eat the demonstrations. These demonstrations are an effective teaching tool for all ages, and can be adapted for cultural, culinary, and ethnic differences among the students.

  8. Optical payload for lasercomm science (OPALS) link validation during operations from the ISS

    NASA Astrophysics Data System (ADS)

    Biswas, Abhijit; Oaida, Bogdan; Andrews, Kenneth S.; Kovalik, Joseph M.; Abrahamson, Matthew; Wright, Malcolm W.

    2015-03-01

    In mid-2014 several day and nighttime links under diverse atmospheric conditions were completed using the Optical Payload for Lasercomm Science (OPALS) flight system on-board the International Space Station (ISS). In this paper we compare measured optical power and its variance at either end of the link with predictions that include atmospheric propagation models. For the 976 nm laser beacon mean power transmitted from the ground to the ISS the predicted mean irradiance of tens of microwatts per square meter close to zenith and its decrease with range and increased air mass shows good agreement with predictions. The irradiance fluctuations sampled at 100 Hz also follow the expected increase in scintillation with air mass representative of atmospheric coherence lengths at zenith at 500 nm in the 3-8 cm range. The downlink predicted power of hundreds of nanowatts was also reconciled within the uncertainty of the atmospheric losses. Expected link performance with uncoded bit-error rates less than 1E-4 required for the Reed- Solomon code to correct errors for video, text and file transmissions was verified. The results of predicted and measured powers and fluctuations suggest the need for further study and refinement.

  9. Science Activities That Work: Perceptions of Primary School Teachers

    NASA Astrophysics Data System (ADS)

    Appleton, Ken

    2002-06-01

    Many primary school teachers in Australia tend to be reluctant to teach science, partly because they are not confident in science and have limited science background knowledge. However, quite a number of primary school teachers still manage to teach some science. When they plan to teach science, many of them use the term science activities that work. Such activities seem to be related to science pedagogical content knowledge for some primary teachers. In order to better understand what the term activities that work means, twenty teachers from several schools were interviewed and asked what they understood by this expression. Themes that emerged suggest that activities that work are hands on, are interesting and motivating for the children, have a clear outcome or result, are manageable in the classroom, use equipment that is readily available, and are preferably used in a context where science is integrated into themes. Implications for curriculum and for preservice teacher education are considered.

  10. LANSCE nuclear science facilities and activities

    SciTech Connect

    Nelson, Ronald O

    2010-01-01

    Nuclear science activities at the Los Alamos Neutron Science Center (LANSCE) encompass measurements spanning the neutron energy range from thermal to 600 MeV. The neutron sources use spallation of the LANSCE 800 MeV pulsed proton beam with the time-of-flight technique to measure properties of neutron-induced reactions as a function of energy over this large energy range. Current experiments are conducted at the Lujan Center moderated neutron source, the unmoderated WNR target, and with a lead-slowing-down spectrometer. Instruments in use include the DANCE array of BaF{sub 2} scintillators for neutron capture studies, the FIGARO array of liquid scintillator neutron detectors, the GEANIE array of high-resolution HPGe x-ray and gamma-ray detectors, and a number of fission chambers, and other detectors. The LANL capabilities for production and handling of radioactive materials coupled with the neutron sources and detectors at LANSCE are enabling new and challenging measurements for a variety of applications including nuclear energy and nuclear astrophysics. An overview of recent research and examples of results is presented.

  11. Science Activity Planner for the MER Mission

    NASA Technical Reports Server (NTRS)

    Norris, Jeffrey S.; Crockett, Thomas M.; Fox, Jason M.; Joswig, Joseph C.; Powell, Mark W.; Shams, Khawaja S.; Torres, Recaredo J.; Wallick, Michael N.; Mittman, David S.

    2008-01-01

    The Maestro Science Activity Planner is a computer program that assists human users in planning operations of the Mars Explorer Rover (MER) mission and visualizing scientific data returned from the MER rovers. Relative to its predecessors, this program is more powerful and easier to use. This program is built on the Java Eclipse open-source platform around a Web-browser-based user-interface paradigm to provide an intuitive user interface to Mars rovers and landers. This program affords a combination of advanced display and simulation capabilities. For example, a map view of terrain can be generated from images acquired by the High Resolution Imaging Science Explorer instrument aboard the Mars Reconnaissance Orbiter spacecraft and overlaid with images from a navigation camera (more precisely, a stereoscopic pair of cameras) aboard a rover, and an interactive, annotated rover traverse path can be incorporated into the overlay. It is also possible to construct an overhead perspective mosaic image of terrain from navigation-camera images. This program can be adapted to similar use on other outer-space missions and is potentially adaptable to numerous terrestrial applications involving analysis of data, operations of robots, and planning of such operations for acquisition of scientific data.

  12. Linking Plagioclase Zoning Patterns to Active Magma Processes

    NASA Astrophysics Data System (ADS)

    Izbekov, P. E.; Nicolaysen, K. P.; Neill, O. K.; Shcherbakov, V.; Plechov, P.; Eichelberger, J. C.

    2015-12-01

    Plagioclase, one of the most common and abundant mineral phases in volcanic products, will vary in composition in response to changes in temperature, pressure, composition of the ambient silicate melt, and melt H2O concentration. Changes in these parameters may cause dissolution or growth of plagioclase crystals, forming characteristic textural and compositional variations (zoning patterns), the complete core-to-rim sequence of which describes events experienced by an individual crystal from its nucleation to the last moments of its growth. Plagioclase crystals in a typical volcanic rock may look drastically dissimilar despite their spatial proximity and the fact that they have erupted together. Although they shared last moments of their growth during magma ascent and eruption, their prior experiences could be very different, as plagioclase crystals often come from different domains of the same magma system. Distinguishing similar zoning patterns, correlating them across the entire population of plagioclase crystals, and linking these patterns to specific perturbations in the magmatic system may provide additional perspective on the variety, extent, and timing of magma processes at active volcanic systems. Examples of magma processes, which may be distinguished based on plagioclase zoning patterns, include (1) cooling due to heat loss, (2) heating and/or pressure build up due to an input of new magmatic material, (3) pressure drop in response to magma system depressurization, and (4) crystal transfer between different magma domains/bodies. This review will include contrasting examples of zoning patters from recent eruptions of Karymsky, Bezymianny, and Tolbachik Volcanoes in Kamchatka, Augustine and Cleveland Volcanoes in Alaska, as well as from the drilling into an active magma body at Krafla, Iceland.

  13. Exosomes: The Link between GPCR Activation and Metastatic Potential?

    PubMed Central

    Isola, Allison L.; Chen, Suzie

    2016-01-01

    The activation of G-Protein Coupled Receptors (GPCRs) by their respective ligands initiates a cascade of multiple signaling processes within the cell, regulating growth, metabolism and other essential cellular functions. Dysregulation and aberrant expression of these GPCRs and their subsequent signaling cascades are associated with many different types of pathologies, including cancer. The main life threatening complication in patients diagnosed with cancer is the dissemination of cells from the primary tumor to distant vital organs within the body, metastasis. Communication between the primary tumor, immune system, and the site of future metastasis are some of the key events in the early stages of metastasis. It has been postulated that the communication is mediated by nanovesicles that, under non-pathological conditions, are released by normal cells to relay signals to other cells in the body. These nanovesicles are called exosomes, and are utilized by the tumor cell to influence changes within the recipient cell, such as bone marrow progenitor cells, and cells within the site of future metastatic growth, in order to prepare the site for colonization. Tumor cells have been shown to release an increased number of exosomes when compared to their normal cell counterpart. Exosome production and release are regulated by proteins involved in localization, degradation and size of the multivesicular body, whose function may be altered within cancer cells, resulting in the release of an increased number of these vesicles. This review investigates the possibility of GPCR signaling cascades acting as the upstream activator of proteins involved in exosome production and release, linking a commonly targeted trans-membrane protein class with cellular communication utilized by tumor cells in early stages of metastasis. PMID:27092178

  14. Marine governance in the English Channel (La Manche): Linking science and management.

    PubMed

    Glegg, G; Jefferson, R; Fletcher, S

    2015-06-30

    The English Channel is one of the world's busiest sea areas with intense shipping and port activity juxtaposed with recreation, communications and important conservation areas. Opportunities for marine renewable energy vie with existing activities for space. The current governance of the English Channel is reviewed and found to lack integration between countries, sectors, legislation and scientific research. Recent developments within the EU's marine management frameworks are significantly altering our approach to marine governance and this paper explores the implications of these new approaches to management of the English Channel. Existing mechanisms for cross-Channel science and potential benefits of an English Channel scale perspective are considered. In conclusion, current management practices are considered against the 12 Malawi Principles of the ecosystem approach resulting in proposals for enhancing governance of the region through science at the scale of the English Channel.

  15. Essential Laboratory Activities Guide. Secondary Science.

    ERIC Educational Resources Information Center

    Duval County Schools, Jacksonville, FL.

    This teacher's guide was developed for use in junior and senior high schools in Duval County, Jacksonville, Florida, for the purpose of identifying those secondary science laboratory experiences which are essential to the development of science content knowledge and competency in handling science laboratory equipment and consumables. The guide…

  16. What Can Funders Do to Better Link Science with Decisions? Case Studies of Coastal Communities and Climate Change

    NASA Astrophysics Data System (ADS)

    Matso, Kalle E.; Becker, Mimi L.

    2014-12-01

    Many reports and studies have noted that a significant portion of problem-oriented coastal science does not actually link to decisions. Here, three competitively funded project case studies are studied to determine what funders can and should do to better link science with decisions. The qualitative analysis used for this study indicates that the studied program was seen as being unusually attentive to the issue of linking science to decisions, as opposed to simply generating new knowledge. Nevertheless, much of the data indicate that funders can and should do more. Three ideas figured most prominently in the qualitative data: (1) funders should do more to ensure that the problem itself is defined more thoroughly with people who are envisioned as potential users of the science; (2) funders need to allocate more resources and attention to communicating effectively (with users) throughout the project; and (3) funders need to demand more engagement of users throughout the project. These findings have important implications for how funders review and support science, especially when competitive processes are used. Most importantly, funders should adjust what kind of science they ask for. Secondly, funders need to change who is involved in the review process. Currently, review processes focus on knowledge generation, which means that the reviewers themselves have expertise in that area. Instead, review panels should be balanced between those who focus on knowledge generation and those who focus on linking knowledge to decisions; this is a separate but critical discipline currently left out of the review process.

  17. Activities of citrate synthase and NAD+-linked and NADP+-linked isocitrate dehydrogenase in muscle from vertebrates and invertebrates.

    PubMed Central

    Alp, P R; Newsholme, E A; Zammit, V A

    1976-01-01

    1. The activities of citrate synthase, NAD+-linked and NADP+-linked isocitrate dehydrogenase were measured in muscles from a large number of animals, in order to provide some indication of the importance of the citric acid cycle in these muscles. According to the differences in enzyme activities, the muscles can be divided into three classes. First, in a number of both vertebrate and invertebrate muscles, the activities of all three enzymes are very low. It is suggested that either the muscles use energy at a very low rate or they rely largely on anaerobic glycolysis for higher rates of energy formation. Second, most insect flight muscles contain high activities of citrate synthase and NAD+-linked isocitrate dehydrogenase, but the activities of the NADP+-linked enzyme are very low. The high activities indicate the dependence of insect flight on energy generated via the citric acid cycle. The flight muscles of the beetles investigated contain high activities of both isocitrate dehydrogenases. Third, other muscles of both vertebrates and invertebrates contain high activities of citrate synthase and NADP+-liniked isocitrate dehydrogenase. Many, if not all, of these muscles are capable of sustained periods of mechanical activity (e.g. heart muscle, pectoral muscles of some birds). Consequently, to support this activity fuel must be supplied continually to the muscle via the circulatory system which, in most animals, also transports oxygen so that energy can be generated by complete oxidation of the fuel. It is suggested that the low activities of NAD+-linked isocitrate dehydrogenase in these muscles may be involved in oxidation of isocitrate in the cycle when the muscles are at rest. 2. A comparison of the maximal activities of the enzymes with the maximal flux through the cycle suggests that, in insect flight muscle, NAD+-linked isocitrate dehydrogenase catalyses a non-equilibrium reaction and citrate synthease catalyses a near-equilibrium reaction. In other muscles

  18. Energy and Change. Elementary Science Activity Series, Volume 3.

    ERIC Educational Resources Information Center

    Blackwell, Frank F.

    This book is number 3 of a series of elementary science books that presents a wealth of ideas for science activities for the elementary school teacher. Each activity includes a standard set of information designed to help teachers determine the activity's appropriateness for their students, plan its implementation, and help children focus on a…

  19. Family Science Activities for Adult Basic and Literacy Education.

    ERIC Educational Resources Information Center

    Community Action Southwest, Waynesburg, PA.

    A staff development project created a series of family science activities to be used in adult basic and literacy education (ABLE) and family literacy programs and a training guide for staff and volunteers. The training guide provides background principles and concepts for science activities. The activities identify materials and indicate ways the…

  20. Structure and Form. Elementary Science Activity Series, Volume 2.

    ERIC Educational Resources Information Center

    Blackwell, Frank F.

    This book is number 2 of a series of elementary science books that presents a wealth of ideas for science activities for the elementary school teacher. Each activity includes a standard set of information designed to help teachers determine the activity's appropriateness for their students, plan its implementation, and help children focus on a…

  1. Fun with Hands-on Science Activities for Elementary Teachers.

    ERIC Educational Resources Information Center

    Barry, Dana M.

    This document contains hands-on activities in science that make use of balloons and are fun and stimulating as well as challenging. By actively participating in these activities, students can develop science process and critical thinking skills as well as technical and measuring skills. Topics include Air as Matter, Pressure, Chemical Change,…

  2. Innovative Hands-on Activities for Middle School Science.

    ERIC Educational Resources Information Center

    Barry, Dana M.

    This paper contains some hands-on activities that relate science to art and language arts. The focus is placed on middle schools and activities engage students in the discovery that chemicals are used to draw and color. Students also read and write poetry and literature that employ science-related topics. A number of spin-off activities are…

  3. Linking Science Analysis with Observation Planning: A Full Circle Data Lifecycle

    NASA Technical Reports Server (NTRS)

    Grosvenor, Sandy; Jones, Jeremy; Koratkar, Anuradha; Li, Connie; Mackey, Jennifer; Neher, Ken; Wolf, Karl; Obenschain, Arthur F. (Technical Monitor)

    2001-01-01

    A clear goal of the Virtual Observatory (VO) is to enable new science through analysis of integrated astronomical archives. An additional and powerful possibility of the VO is to link and integrate these new analyses with planning of new observations. By providing tools that can be used for observation planning in the VO, the VO will allow the data lifecycle to come full circle: from theory to observations to data and back around to new theories and new observations. The Scientist's Expert Assistant (SEA) Simulation Facility (SSF) is working to combine the ability to access existing archives with the ability to model and visualize new observations. Integrating the two will allow astronomers to better use the integrated archives of the VO to plan and predict the success of potential new observations more efficiently, The full circle lifecycle enabled by SEA can allow astronomers to make substantial leaps in the quality of data and science returns on new observations. Our paper examines the exciting potential of integrating archival analysis with new observation planning, such as performing data calibration analysis on archival images and using that analysis to predict the success of new observations, or performing dynamic signal-to-noise analysis combining historical results with modeling of new instruments or targets. We will also describe how the development of the SSF is progressing and what have been its successes and challenges.

  4. Linking Science Analysis with Observation Planning: A Full Circle Data Lifecycle

    NASA Technical Reports Server (NTRS)

    Jones, Jeremy; Grosvenor, Sandy; Wolf, Karl; Li, Connie; Koratkar, Anuradha; Powers, Edward I. (Technical Monitor)

    2001-01-01

    A clear goal of the Virtual Observatory (VO) is to enable new science through analysis of integrated astronomical archives. An additional and powerful possibility of the VO is to link and integrate these new analyses with planning of new observations. By providing tools that can be used for observation planning in the VO, the VO will allow the data lifecycle to come full circle: from theory to observations to data and back around to new theories and new observations. The Scientist's Expert Assistant (SEA) Simulation Facility (SSF) is working to combine the ability to access existing archives with the ability to model and visualize new observations. Integrating the two will allow astronomers to better use the integrated archives of the VO to plan and predict the success of potential new observations. The full circle lifecycle enabled by SEA can allow astronomers to make substantial leaps in the quality of data and science returns on new observations. Our paper will examine the exciting potential of integrating archival analysis with new observation planning, such as performing data calibration analysis on archival images and using that analysis to predict the success of new observations, or performing dynamic signal-to-noise analysis combining historical results with modeling of new instruments or targets. We will also describe how the development of the SSF is progressing and what has been its successes and challenges.

  5. Family Science Night: Fun Tips, Activities, and Ideas

    ERIC Educational Resources Information Center

    Connell, Shelley S.

    2013-01-01

    At last! A practical, readable guide for teachers, school leaders, and parent/teacher associations that shows how to plan fun, hands-on science nights! Get easy-to-implement, content-rich tips and ideas that will cultivate positive attitudes toward science! Learn how to involve and actively engage families in their children's science education.…

  6. Accommodating Students with Disabilities in Soil Science Activities

    ERIC Educational Resources Information Center

    Langley-Turnbaugh, S. J.; Murphy, Kate; Levin, E.

    2004-01-01

    Soil science education is lacking in terms of accommodations for persons with disabilities. Individuals with disabilities are often excluded from soil science activities in school, and from soil science careers. GLOBE (Global Learning Observations to Benefit the Environment) is a worldwide, hands-on primary and secondary school-based education and…

  7. Science Teaching and Learning Activities and Students' Engagement in Science

    ERIC Educational Resources Information Center

    Hampden-Thompson, Gillian; Bennett, Judith

    2013-01-01

    The purpose of this analysis is to describe the variation in students' reports of engagement in science across science teaching and learning activities. In addition, this study examines student and school characteristics that may be associated with students' levels of engagement in science. Data are drawn from the Programme for…

  8. Teachers' Willingness to Adopt Nature of Science Activities Following a Physical Science Professional Development

    ERIC Educational Resources Information Center

    Donnelly, Lisa A.; Argyle, Sean

    2011-01-01

    The major science education reform documents emphasize the need for K-12 students to have a robust understanding of nature of science (NOS), and inservice teachers consequently need to develop their NOS teaching repertoires. This study investigated the extent to which science teachers were willing to adopt new strategies and activities for…

  9. Living science: Science as an activity of living beings.

    PubMed

    MacLennan, Bruce J

    2015-12-01

    The philosophy of science should accommodate itself to the facts of human existence, using all aspects of human experience to adapt more effectively, as individuals, species, and global ecosystem. This has several implications: (1) Our nature as sentient beings interacting with other sentient beings requires the use of phenomenological methods to investigate consciousness. (2) Our embodied, situated, purposeful physical interactions with the world are the foundation of scientific understanding. (3) Aristotle's four causes are essential for understanding living systems and, in particular, the final cause aids understanding the role of humankind, and especially science, in the global ecosystem. (4) In order to fulfill this role well, scientists need to employ the full panoply of human faculties. These include the consciousness faculties (thinking, sensation, feeling, intuition), and therefore, as advocated by many famous scientists, we should cultivate our aesthetic sense, emotions, imagination, and intuition. Our unconscious faculties include archetypal structures common to all humans, which can guide scientific discovery. By striving to engage the whole of human nature, science will fulfill better its function for humans and the global ecosystem.

  10. The QWeCI Project: seamlessly linking climate science to society

    NASA Astrophysics Data System (ADS)

    Morse, A. P.; Caminade, C.; Jones, A. E.; MacLeod, D.; Heath, A. E.

    2012-04-01

    The EU FP7 QWeCI project Quantifying Weather and Climate Impacts on health in developing countries (www.liv.ac.uk/qweci) has 13 partners with 7 of these in Africa. The geographical focus of the project is in Senegal, Ghana and Malawi. In all three countries the project has a strong scientific dissemination outlook as well as having field based surveillance programmes in Ghana and Senegal to understand more about the local parameters controlling the transmission of malaria and in Senegal of Rift Valley fever. The project has a strong and active climate science activity in using hindcasts of the new System 4 seasonal forecasting system at ECMWF; to further develop the use of monthly to seasonal forecasts from ensemble prediction systems; within project downscaling development; the assessment of decadal ensemble prediction systems; and the development and testing of vector borne disease models for malaria and Rift Valley fever. In parallel with the science programme the project has a large outreach activity involving regular communication and bi-lateral exchanges, science and decision maker focused workshops. In Malawi a long range WiFi network has been established for the dissemination of data. In Senegal where they is a concentration of partners and stakeholders the project is gaining a role as a catalyst for wider health and climate related activity within government departments and national research bodies along with the support and involvement of local communities. Within these wider community discussions we have interactive inputs from African and European scientists who are partners in the project. This paper will show highlights of the work completed so far and give an outline to future development and to encourage a wider user interaction from outside of the current project team and their direct collaborators.

  11. Science for Energy Technology: Strengthening the Link Between Basic Research and Industry

    SciTech Connect

    2010-04-01

    The nation faces two severe challenges that will determine our prosperity for decades to come: assuring clean, secure, and sustainable energy to power our world, and establishing a new foundation for enduring economic and jobs growth. These challenges are linked: the global demand for clean sustainable energy is an unprecedented economic opportunity for creating jobs and exporting energy technology to the developing and developed world. But achieving the tremendous potential of clean energy technology is not easy. In contrast to traditional fossil fuel-based technologies, clean energy technologies are in their infancy, operating far below their potential, with many scientific and technological challenges to overcome. Industry is ultimately the agent for commercializing clean energy technology and for reestablishing the foundation for our economic and jobs growth. For industry to succeed in these challenges, it must overcome many roadblocks and continuously innovate new generations of renewable, sustainable, and low-carbon energy technologies such as solar energy, carbon sequestration, nuclear energy, electricity delivery and efficiency, solid state lighting, batteries and biofuels. The roadblocks to higher performing clean energy technology are not just challenges of engineering design but are also limited by scientific understanding.Innovation relies on contributions from basic research to bridge major gaps in our understanding of the phenomena that limit efficiency, performance, or lifetime of the materials or chemistries of these sustainable energy technologies. Thus, efforts aimed at understanding the scientific issues behind performance limitations can have a real and immediate impact on cost, reliability, and performance of technology, and ultimately a transformative impact on our economy. With its broad research base and unique scientific user facilities, the DOE Office of Basic Energy Sciences (BES) is ideally positioned to address these needs. BES has laid

  12. Sublime Science

    ERIC Educational Resources Information Center

    Girod, Mark

    2007-01-01

    One of the shortcomings in most efforts to integrate art and science is that many people have a shallow understanding of art, which inevitably leads to shallow connections between art and science. Coloring drawings of planets, building sculptures of volcanoes, and decorating scientific diagrams are fine activities, but they do not link science and…

  13. Hands-On Environmental Science Activities. Teacher's Edition. First Edition.

    ERIC Educational Resources Information Center

    Kutscher, Eugene

    The ability of students to go beyond facts and to think critically, while at the same time enjoying and valuing the learning process, is fundamental to science and environmentalism. This book provides enrichment activities for the science curriculum that provide concrete connections with important world events. Each activity is self-contained and…

  14. Agricultural Education Science Activity--Nos. AS 1-4.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Agricultural Curriculum Materials Service.

    This packet contains four science learning activities on the subject of animal science that can be used in agricultural education courses. The activities cover these topics: (1) identifying internal parasites in domestic livestock; (2) the effect of feed preparation on feed palatability and consumption; (3) determining the absorption abilities of…

  15. Career Activities in Science: Grades 7-12.

    ERIC Educational Resources Information Center

    Sleep, Gerald; And Others

    The curriculum guide attempts to assemble select activities that represent skills related to careers in science. These learning activities are designed to give junior and senior high school students opportunities to explore concepts and processes in many science-related careers. The broad areas covered are biology, chemistry, physics, and earth…

  16. Knowledge-Building Activity Structures in Japanese Elementary Science Pedagogy

    ERIC Educational Resources Information Center

    Oshima, Jun; Oshima, Ritsuko; Murayama, Isao; Inagaki, Shigenori; Takenaka, Makiko; Yamamoto, Tomokazu; Yamaguchi, Etsuji; Nakayama, Hayashi

    2006-01-01

    The purpose of this study is to refine Japanese elementary science activity structures by using a CSCL approach to transform the classroom into a knowledge-building community. We report design studies on two science lessons in two consecutive years and describe the progressive refinement of the activity structures. Through comparisons of student…

  17. Engineering Design Activities and Conceptual Change in Middle School Science

    ERIC Educational Resources Information Center

    Schnittka, Christine G.

    2009-01-01

    The purpose of this research was to investigate the impact of engineering design classroom activities on conceptual change in science, and on attitudes toward and knowledge about engineering. Students were given a situated learning context and a rationale for learning science in an active, inquiry-based method, and worked in small collaborative…

  18. The Pleasures and the Pitfalls of Plant Science Activities.

    ERIC Educational Resources Information Center

    Hershey, David R.

    2000-01-01

    Classroom plant activities have long been inexpensive, easy to do, and fun for students, and have become more central to biology teaching. Introduces some plant science activities and their pleasures and pitfalls. (ASK)

  19. Sciencing with Mother Goose: Observation Activities with Chicken Little.

    ERIC Educational Resources Information Center

    Angus, Carolyn

    1996-01-01

    Provides sample observation activities to accompany the nursery tale of Chicken Little. Includes five activities that involve the skills of observing, communicating, comparing, ordering, and categorizing to engage students in hands-on science. (DDR)

  20. Linking Disparate Datasets of the Earth Sciences with the SemantEco Annotator

    NASA Astrophysics Data System (ADS)

    Seyed, P.; Chastain, K.; McGuinness, D. L.

    2013-12-01

    Use of Semantic Web technologies for data management in the Earth sciences (and beyond) has great potential but is still in its early stages, since the challenges of translating data into a more explicit or semantic form for immediate use within applications has not been fully addressed. In this abstract we help address this challenge by introducing the SemantEco Annotator, which enables anyone, regardless of expertise, to semantically annotate tabular Earth Science data and translate it into linked data format, while applying the logic inherent in community-standard vocabularies to guide the process. The Annotator was conceived under a desire to unify dataset content from a variety of sources under common vocabularies, for use in semantically-enabled web applications. Our current use case employs linked data generated by the Annotator for use in the SemantEco environment, which utilizes semantics to help users explore, search, and visualize water or air quality measurement and species occurrence data through a map-based interface. The generated data can also be used immediately to facilitate discovery and search capabilities within 'big data' environments. The Annotator provides a method for taking information about a dataset, that may only be known to its maintainers, and making it explicit, in a uniform and machine-readable fashion, such that a person or information system can more easily interpret the underlying structure and meaning. Its primary mechanism is to enable a user to formally describe how columns of a tabular dataset relate and/or describe entities. For example, if a user identifies columns for latitude and longitude coordinates, we can infer the data refers to a point that can be plotted on a map. Further, it can be made explicit that measurements of 'nitrate' and 'NO3-' are of the same entity through vocabulary assignments, thus more easily utilizing data sets that use different nomenclatures. The Annotator provides an extensive and searchable

  1. Findings from an Independent Evaluation of the AMNH's Online Seminars on Science Course: "The Link between Dinosaurs and Birds"

    ERIC Educational Resources Information Center

    Inverness Research, 2008

    2008-01-01

    Inverness Research studied the American Museum of Natural History's (AMNH) Seminars on Science program for eight years, from its inception in 1998 to 2006. This paper presents teacher survey ratings for "The Link between Dinosaurs and Birds", along with profiles of three teachers who took the course. Course takers report on the annual follow-up…

  2. Still More Science Activities. 20 Exciting Activities To Do!

    ERIC Educational Resources Information Center

    Smithsonian Institution, Washington, DC.

    Science and technology affect every facet of human life. By the 21st century, society will demand that all of its citizens possess basic competencies in the fundamentals of science and the use of technology. As science increasingly becomes the dominant subject of the work place, it is important to begin developing within children an understanding…

  3. Linking Big and Small Data Across the Social, Engineering, and Earth Sciences

    NASA Astrophysics Data System (ADS)

    Chen, R. S.; de Sherbinin, A. M.; Levy, M. A.; Downs, R. R.

    2014-12-01

    The challenges of sustainable development cut across the social, health, ecological, engineering, and Earth sciences, across a wide range of spatial and temporal scales, and across the spectrum from basic to applied research and decision making. The rapidly increasing availability of data and information in digital form from a variety of data repositories, networks, and other sources provides new opportunities to link and integrate both traditional data holdings as well as emerging "big data" resources in ways that enable interdisciplinary research and facilitate the use of objective scientific data and information in society. Taking advantage of these opportunities not only requires improved technical and scientific data interoperability across disciplines, scales, and data types, but also concerted efforts to bridge gaps and barriers between key communities, institutions, and networks. Given the long time perspectives required in planning sustainable approaches to development, it is also imperative to address user requirements for long-term data continuity and stewardship by trustworthy repositories. We report here on lessons learned by CIESIN working on a range of sustainable development issues to integrate data across multiple repositories and networks. This includes CIESIN's roles in developing policy-relevant climate and environmental indicators, soil data for African agriculture, and exposure and risk measures for hazards, disease, and conflict, as well as CIESIN's participation in a range of national and international initiatives related both to sustainable development and to open data access, interoperability, and stewardship.

  4. Lowering the Barriers to Integrative Aquatic Ecosystem Science: Semantic Provenance, Open Linked Data, and Workflows

    NASA Astrophysics Data System (ADS)

    Harmon, T.; Hofmann, A. F.; Utz, R.; Deelman, E.; Hanson, P. C.; Szekely, P.; Villamizar, S. R.; Knoblock, C.; Guo, Q.; Crichton, D. J.; McCann, M. P.; Gil, Y.

    2011-12-01

    Environmental cyber-observatory (ECO) planning and implementation has been ongoing for more than a decade now, and several major efforts have recently come online or will soon. Some investigators in the relevant research communities will use ECO data, traditionally by developing their own client-side services to acquire data and then manually create custom tools to integrate and analyze it. However, a significant portion of the aquatic ecosystem science community will need more custom services to manage locally collected data. The latter group represents enormous intellectual capacity when one envisions thousands of ecosystems scientists supplementing ECO baseline data by sharing their own locally intensive observational efforts. This poster summarizes the outcomes of the June 2011 Workshop for Aquatic Ecosystem Sustainability (WAES) which focused on the needs of aquatic ecosystem research on inland waters and oceans. Here we advocate new approaches to support scientists to model, integrate, and analyze data based on: 1) a new breed of software tools in which semantic provenance is automatically created and used by the system, 2) the use of open standards based on RDF and Linked Data Principles to facilitate sharing of data and provenance annotations, 3) the use of workflows to represent explicitly all data preparation, integration, and processing steps in a way that is automatically repeatable. Aquatic ecosystems workflow exemplars are provided and discussed in terms of their potential broaden data sharing, analysis and synthesis thereby increasing the impact of aquatic ecosystem research.

  5. The Links between Parent Behaviors and Boys' and Girls' Science Achievement Beliefs

    ERIC Educational Resources Information Center

    Bhanot, Ruchi T.; Jovanovic, Jasna

    2009-01-01

    This study examined whether parental involvement in children's science schoolwork (i.e., discussions about science, homework helping and encouragement of science interest) varies for boys and girls, and how these behaviors relate to children's science achievement beliefs (i.e., ability perceptions and task-value) at the end of a school year. We…

  6. Linking research to practice: the rise of evidence-based health sciences librarianship*

    PubMed Central

    Marshall, Joanne Gard

    2014-01-01

    Purpose: The lecture explores the origins of evidence-based practice (EBP) in health sciences librarianship beginning with examples from the work of Janet Doe and past Doe lecturers. Additional sources of evidence are used to document the rise of research and EBP as integral components of our professional work. Methods: Four sources of evidence are used to examine the rise of EBP: (1) a publication by Doe and research-related content in past Doe lectures, (2) research-related word usage in articles in the Bulletin of the Medical Library Association and Journal of the Medical Library Association between 1961 and 2010, (3) Medical Library Association activities, and (4) EBP as an international movement. Results: These sources of evidence confirm the rise of EBP in health sciences librarianship. International initiatives sparked the rise of evidence-based librarianship and continue to characterize the movement. This review shows the emergence of a unique form of EBP that, although inspired by evidence-based medicine (EBM), has developed its own view of evidence and its application in library and information practice. Implications: Health sciences librarians have played a key role in initiating, nurturing, and spreading EBP in other branches of our profession. Our close association with EBM set the stage for developing our own EBP. While we relied on EBM as a model for our early efforts, we can observe the continuing evolution of our own unique approach to using, creating, and applying evidence from a variety of sources to improve the quality of health information services. PMID:24415915

  7. Energy Storage. Teachers Guide. Science Activities in Energy.

    ERIC Educational Resources Information Center

    Jacobs, Mary Lynn, Ed.

    Included in this science activities energy package for students in grades 4-10 are 12 activities related to energy storage. Each activity is outlined on the front and back of a single sheet and is introduced by a key question. Most of the activities can be completed in the classroom with materials readily available in any community. Among the…

  8. Science/Technology/Society: Activities and Resources for Secondary Science and Social Studies.

    ERIC Educational Resources Information Center

    Singleton, Laurel R., Ed.

    This book contains 45 activities suitable for use in secondary science and social studies classes. Except for the first four activities, which are quick attention getters, all the activities are presented in a standard format. Each begins with an introduction, that provides a brief overview of the activity's content and the teaching strategies…

  9. Computer Science and Telecommunications Board summary of activities

    SciTech Connect

    Blumenthal, M.S.

    1992-03-27

    The Computer Science and Telecommunications Board (CSTB) considers technical and policy issues pertaining to computer science, telecommunications, and associated technologies. CSTB actively disseminates the results of its completed projects to those in a position to help implement their recommendations or otherwise use their insights. It provides a forum for the exchange of information on computer science, computing technology, and telecommunications. This report discusses the major accomplishments of CSTB.

  10. The Effect of Physical Activity on Science Competence and Attitude towards Science Content

    NASA Astrophysics Data System (ADS)

    Klinkenborg, Ann Maria

    This study examines the effect of physical activity on science instruction. To combat the implications of physical inactivity, schools need to be willing to consider all possible opportunities for students to engage in moderate-to-vigorous physical activity (MVPA). Integrating physical activity with traditional classroom content is one instructional method to consider. Researchers have typically focused on integration with English/language arts (ELA) and mathematics. The purpose of this study was to determine the effect of physical activity on science competence and attitude towards science. Fifty-three third grade children participated in this investigation; one group received science instruction with a physical activity intervention while the other group received traditional science instruction. Participants in both groups completed a modified version of What I Really Think of Science attitude scale (Pell & Jarvis, 2001) and a physical science test of competence prior to and following the intervention. Children were videotaped during science instruction and their movement coded to measure the proportion of time spent in MVPA. Results revealed that children in the intervention group demonstrated greater MVPA during the instructional period. A moderate to large effect size (partial eta squared = .091) was seen in the intervention group science competence post-test indicating greater understanding of force, motion, work, and simple machines concepts than that of the control group who were less physically active. There was no statistically significant attitude difference between the intervention and control groups post-test, (F(1,51) = .375, p = .543). These results provide evidence that integration can effectively present physical science content and have a positive impact on the number of minutes of health-enhancing physical activity in a school day.

  11. Community-based carbon sequestration in East Africa: Linking science and sustainability

    NASA Astrophysics Data System (ADS)

    Hultman, N. E.

    2004-12-01

    International agreements on climate change have set the stage for an expanding market for greenhouse gas emissions reduction credits. Projects that can generate credits for trading are diverse, but one of the more controversial types involve biological carbon sequestration. For several reasons, most of the activity on these "sinks" projects has been in Latin America and Southeast Asia. Yet people in sub-saharan Africa could benefit from properly implemented projects. This poster will discuss estimates of the potential and risks of such projects in East Africa, and will describe in detail a case study located in central Tanzania and now part of the World Bank's BioCarbon Fund portfolio. Understanding climate variability and risk can effectively link international agreements on climate change, local realities of individual projects, and the characteristics of targeted ecosystems.

  12. Science Learning: A Path Analysis of Its Links with Reading Comprehension, Question-Asking in Class and Science Achievement

    ERIC Educational Resources Information Center

    Cano, Francisco; García, Ángela; Berbén, A. B. G.; Justicia, Fernando

    2014-01-01

    The purpose of this research was to build and test a conceptual model of the complex interrelationships between students' learning in science (learning approaches and self-regulation), their reading comprehension, question-asking in class and science achievement. These variables were measured by means of a test and a series of questionnaires…

  13. Ideas and Activities for Physical Science.

    ERIC Educational Resources Information Center

    Chiappetta, Eugene L., Ed.

    This manual is designed to supplement an existing physical science curriculum and to assist in providing the learning experiences required to implement an effective course. The first chapter outlines the purposes of this manual and provides a set of teaching tips. Topics such as electricity, wave motion, light, sound, periodic table and nuclear…

  14. Designing Inquiry-Oriented Science Lab Activities

    ERIC Educational Resources Information Center

    Longo, Christopher M.

    2011-01-01

    Mr. Smith and Ms. D'Amico are two veteran science teachers in a well-performing school district. Both teachers use weekly lab exercises and experiments as formative assessments. In their middle school classrooms, children are engaged and eager to learn. As students walk into Mr. Smith's classroom, a prescribed, step-by-step procedure of the day's…

  15. Creating Aliens: The Ultimate Life Sciences Activity.

    ERIC Educational Resources Information Center

    Beltramo, Dan

    2001-01-01

    Describes a seven-week project completed by the author's eighth-grade science students (as they studied "the chemistry of living things") in which they designed an alien and its world using the scientific concepts that they learned in class. Compares class presentations using PowerPoint software to presentations using posterboard. (SR)

  16. Science Activities for the Physically Impaired.

    ERIC Educational Resources Information Center

    James, Melodee L.

    1987-01-01

    Describes the nine modules of the SAVI/SELPH program, a hands-on, multisensory science program developed for grade 4-7 visually impaired, orthopedically disabled, learning disabled, deaf, and multihandicapped students. Modules consist of measurement, structures of life, scientific reasoning, communication, magnetism and electricity, mixtures and…

  17. Activities in Planetary Geology for the Physical and Earth Sciences.

    ERIC Educational Resources Information Center

    D'Alli, Richard, Ed.; Greely, Ronald, Ed.

    The activities in this guide deal with concepts in planetary geology, but they can be generalized to illustrate broad problems in the earth sciences. They are designed to supplement or introduce topics usually encountered in earth science courses. The exercises, organized into independent units which can be presented in any order, are appropriate…

  18. Small Wonders. Hands-On Science Activities for Young Children.

    ERIC Educational Resources Information Center

    Perdue, Peggy K.

    Children are natural scientists and are constantly questioning and challenging the world around them. This book is designed to help preschool and primary teachers see the science in common things. It is a book of manipulative activities that are designed to nurture a child's natural curiosity as well as integrate science with other areas.…

  19. Kids Can Make a Difference! Environmental Science Activities.

    ERIC Educational Resources Information Center

    Dashefsky, H. Steven

    This book of more than 160 environmental science activities is designed to help students understand environmental issues, ask questions, and find solutions to the problems. Introductory sections address: (1) the nature of major global problems and a history of environmental concern; (2) basic environmental science terminology and scientific study…

  20. Critters: K-6 Life Science Activities. Project AIMS.

    ERIC Educational Resources Information Center

    Allen, Maureen Murphy; And Others

    Project AIMS (Activities to Integrate Mathematics and Science) has as its purpose the integration of subject matter in grades K-9. Field testing of the curriculum materials produced by AIMS indicates that this integration produces the following beneficial results: (1) mathematics becomes more meaningful, hence more useful; (2) science is…

  1. The ICAP Framework: Linking Cognitive Engagement to Active Learning Outcomes

    ERIC Educational Resources Information Center

    Chi, Michelene T. H.; Wylie, Ruth

    2014-01-01

    This article describes the ICAP framework that defines cognitive engagement activities on the basis of students' overt behaviors and proposes that engagement behaviors can be categorized and differentiated into one of four modes: "Interactive," "Constructive," "Active," and "Passive." The ICAP…

  2. Science Activities: Specific Problems--Some Solutions. Learning in Science Project. Working Paper No. 48.

    ERIC Educational Resources Information Center

    Tasker, Ross, Ed.; Lambert, John, Ed.

    The Learning in Science Project established that children from a young age construct out of their everyday experiences views which they use to explain their world and that these views are remarkably resistant to replacement by scientifically more useful views. Although science lessons tend to be based upon activities which are designed by teachers…

  3. Video: Animals; Electric Current; Force; Science Activities. Learning in Science Project. Working Papers 51-54.

    ERIC Educational Resources Information Center

    Bell, Beverley; And Others

    Four papers to be used in conjunction with video-tapes developed by the Learning in Science Project are presented. Topic areas of the papers focus on: (1) animals; (2) electric current; (3) force; and (4) science activities. The first paper presents transcripts of class discussions focusing on the scientific meaning of the word animal. The second…

  4. Active damping of oscillations in a long compliant manipulator link

    SciTech Connect

    Baker, C.P.; Evans, M.S.; Trudnowski, D.J.; Magee, D.P.

    1993-07-01

    A flexible manipulator test bed consisting of a fifteen foot long fixed-free compliant beam (representing a compliant manipulator link) with a Shilling Titan II dextrous manipulator mounted on its free end has been constructed at Pacific Northwest Laboratory (PNL). A comprehensive dynamic model which includes flexible body effects has been developed at PNL using a commercially available multibody dynamics code. A linearized version of the model is used to develop control strategies which use inertial forces generated by movements of the dextrous manipulator to damp out induced oscillations in the beam. These control strategies are tested on the model and shown to be feasible, and then implemented in the flexible manipulator testbed. Results from the hardware experiments are analyzed and compared with the model results.

  5. Linking geology and health sciences to assess childhood lead poisoning from artisanal gold mining in Nigeria

    USGS Publications Warehouse

    Plumlee, Geoffrey S.; Durant, James T.; Morman, Suzette A.; Neri, Antonio; Wolf, Ruth E.; Dooyema, Carrie A.; Hageman, Philip L.; Lowers, Heather; Fernette, Gregory L.; Meeker, Gregory P.; Benzel, William M.; Driscoll, Rhonda L.; Berry, Cyrus J.; Crock, James G.; Goldstein, Harland L.; Adams, Monique; Bartrem, Casey L.; Tirima, Simba; Behrooz, Behbod; von Lindern, Ian; Brown, Mary Jean

    2013-01-01

    Background: In 2010, Médecins Sans Frontières discovered a lead poisoning outbreak linked to artisanal gold processing in northwestern Nigeria. The outbreak has killed approximately 400 young children and affected thousands more. Objectives: Our aim was to undertake an interdisciplinary geological- and health-science assessment to clarify lead sources and exposure pathways, identify additional toxicants of concern and populations at risk, and examine potential for similar lead poisoning globally. Methods: We applied diverse analytical methods to ore samples, soil and sweep samples from villages and family compounds, and plant foodstuff samples. Results: Natural weathering of lead-rich gold ores before mining formed abundant, highly gastric-bioaccessible lead carbonates. The same fingerprint of lead minerals found in all sample types confirms that ore processing caused extreme contamination, with up to 185,000 ppm lead in soils/sweep samples and up to 145 ppm lead in plant foodstuffs. Incidental ingestion of soils via hand-to-mouth transmission and of dusts cleared from the respiratory tract is the dominant exposure pathway. Consumption of water and foodstuffs contaminated by the processing is likely lesser, but these are still significant exposure pathways. Although young children suffered the most immediate and severe consequences, results indicate that older children, adult workers, pregnant women, and breastfed infants are also at risk for lead poisoning. Mercury, arsenic, manganese, antimony, and crystalline silica exposures pose additional health threats. Conclusions: Results inform ongoing efforts in Nigeria to assess lead contamination and poisoning, treat victims, mitigate exposures, and remediate contamination. Ore deposit geology, pre-mining weathering, and burgeoning artisanal mining may combine to cause similar lead poisoning disasters elsewhere globally.

  6. Linking Geological and Health Sciences to Assess Childhood Lead Poisoning from Artisanal Gold Mining in Nigeria

    PubMed Central

    Durant, James T.; Morman, Suzette A.; Neri, Antonio; Wolf, Ruth E.; Dooyema, Carrie A.; Hageman, Philip L.; Lowers, Heather A.; Fernette, Gregory L.; Meeker, Gregory P.; Benzel, William M.; Driscoll, Rhonda L.; Berry, Cyrus J.; Crock, James G.; Goldstein, Harland L.; Adams, Monique; Bartrem, Casey L.; Tirima, Simba; Behbod, Behrooz; von Lindern, Ian; Brown, Mary Jean

    2013-01-01

    Background: In 2010, Médecins Sans Frontières discovered a lead poisoning outbreak linked to artisanal gold processing in northwestern Nigeria. The outbreak has killed approximately 400 young children and affected thousands more. Objectives: Our aim was to undertake an interdisciplinary geological- and health-science assessment to clarify lead sources and exposure pathways, identify additional toxicants of concern and populations at risk, and examine potential for similar lead poisoning globally. Methods: We applied diverse analytical methods to ore samples, soil and sweep samples from villages and family compounds, and plant foodstuff samples. Results: Natural weathering of lead-rich gold ores before mining formed abundant, highly gastric-bioaccessible lead carbonates. The same fingerprint of lead minerals found in all sample types confirms that ore processing caused extreme contamination, with up to 185,000 ppm lead in soils/sweep samples and up to 145 ppm lead in plant foodstuffs. Incidental ingestion of soils via hand-to-mouth transmission and of dusts cleared from the respiratory tract is the dominant exposure pathway. Consumption of water and foodstuffs contaminated by the processing is likely lesser, but these are still significant exposure pathways. Although young children suffered the most immediate and severe consequences, results indicate that older children, adult workers, pregnant women, and breastfed infants are also at risk for lead poisoning. Mercury, arsenic, manganese, antimony, and crystalline silica exposures pose additional health threats. Conclusions: Results inform ongoing efforts in Nigeria to assess lead contamination and poisoning, treat victims, mitigate exposures, and remediate contamination. Ore deposit geology, pre-mining weathering, and burgeoning artisanal mining may combine to cause similar lead poisoning disasters elsewhere globally. PMID:23524139

  7. Space Research, Education, and Related Activities in the Space Sciences

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The Universities Space Research Association received an award of Cooperative Agreement #NCC5-356 on September 29, 1998. The mission of this activity, know as the Cooperative Program in Space Sciences (CPSS), is to conduct space science research and leading-edge instrumentation and technology development, enable research by the space sciences communities, and to expedite the effective dissemination of space science research, technology, data, and information to the educational community and the general public. To fulfill this mission, USRA recruits and maintains a staff of scientific researchers, operates a series of guest investigator facilities, organizes scientific meetings and workshops, and encourages various interactions with students and university faculty members.

  8. Space Research, Education, and Related Activities In the Space Sciences

    NASA Technical Reports Server (NTRS)

    Black, David

    2002-01-01

    The mission of this activity, known as the Cooperative Program in Space Sciences (CPSS), is to conduct space science research and leading-edge instrumentation and technology development, enable research by the space sciences communities, and to expedite the effective dissemination of space science research, technology, data, and information to the educational community and the general public. To fulfill this mission, the Universities Space Research Association (USRA) recruits and maintains a staff of scientific researchers, operates a series of guest investigator facilities, organizes scientific meetings and workshops, and encourages various interactions with students and university faculty members. This paper is the final report from this now completed Cooperative Agreement.

  9. Space Research, Education, and Related Activities in the Space Sciences

    NASA Technical Reports Server (NTRS)

    Black, David; Marshall, Frank (Technical Monitor)

    2002-01-01

    The Universities Space Research Association received an award of Cooperative Agreement NCC5-356 on September 29, 1998. The mission of this activity, known as the Cooperative Program in Space Sciences (CPSS), is to conduct space science research and leading-edge instrumentation and technology development, enable research by the space sciences communities, and to expedite the effective dissemination of space science research, technology, data, and information to the educational community and the general public. To fulfill this mission, USRA recruits and maintains a staff of scientific researchers, operates a series of guest investigator facilities, organizes scientific meetings and workshops, and encourages various interactions with students and university faculty members.

  10. Hooked on Science: How an Ohio Teacher is Training Students to Be Linked in to Forensics

    ERIC Educational Resources Information Center

    Technology & Learning, 2008

    2008-01-01

    This article features Ohio teacher Carol Fleck's use of videoconferencing in teaching Contemporary BioScience and Genetics. Fleck, who says her initial vision for the class was "science without classroom walls," covers such topics as emerging diseases, bioterrorism, and forensic science. Collaboration between schools is a key part of the course…

  11. Linking online sexual activities to health outcomes among teens.

    PubMed

    O'Sullivan, Lucia F

    2014-01-01

    New digital technologies are highly responsive to many of the developmental needs of adolescents, including their need for intimate connection and social identity. This chapter explores adolescents' use of web-based sexual information, texting and "sexting," online dating sites, role-playing games, and sexually explicit media, and presents new data comparing the interpersonal and intrapersonal health outcomes among youth who engage in online sexual activities to those who do not. Despite the media-stoked concerns surrounding adolescents' participation in online sexual activities, the ubiquity of online activities and close overlap between online and offline activities indicate that this type of behavior should not be pathologized or used as a metric of problem behavior. The chapter concludes with implications for parents, educators, researchers, counselors, and health care providers, a call to challenge our deep discomfort around adolescent sexuality and to harness these technologies in ways that help promote growth and positive development.

  12. Linking online sexual activities to health outcomes among teens.

    PubMed

    O'Sullivan, Lucia F

    2014-01-01

    New digital technologies are highly responsive to many of the developmental needs of adolescents, including their need for intimate connection and social identity. This chapter explores adolescents' use of web-based sexual information, texting and "sexting," online dating sites, role-playing games, and sexually explicit media, and presents new data comparing the interpersonal and intrapersonal health outcomes among youth who engage in online sexual activities to those who do not. Despite the media-stoked concerns surrounding adolescents' participation in online sexual activities, the ubiquity of online activities and close overlap between online and offline activities indicate that this type of behavior should not be pathologized or used as a metric of problem behavior. The chapter concludes with implications for parents, educators, researchers, counselors, and health care providers, a call to challenge our deep discomfort around adolescent sexuality and to harness these technologies in ways that help promote growth and positive development. PMID:24962361

  13. Mars Exploration Rover Operations with the Science Activity Planner

    NASA Technical Reports Server (NTRS)

    Jeffrey S. Norris; Powell, Mark W.; Vona, Marsette A.; Backes, Paul G.; Wick, Justin V.

    2005-01-01

    The Science Activity Planner (SAP) is the primary science operations tool for the Mars Exploration Rover mission and NASA's Software of the Year for 2004. SAP utilizes a variety of visualization and planning capabilities to enable the mission operations team to direct the activities of the Spirit and Opportunity rovers. This paper outlines some of the challenging requirements that drove the design of SAP and discusses lessons learned from the development and use of SAP in mission operations.

  14. Agricultural Science Lab Activities. Instructor Guide. Volume 27, Number 2.

    ERIC Educational Resources Information Center

    Thompson, Gregory W.; And Others

    This instructor guide contains 20 laboratory activities for grades 9-10 Agricultural Science I-II classes. The activities are cross-referenced to Missouri Core Competencies and Key Skills. The activities are organized into the following areas: introductory (microscope use); animal nutrition (absorption of nutrients, bacteria and disease, enzyme…

  15. Career Activities in Science: Grades 7, 8, 9.

    ERIC Educational Resources Information Center

    Boise City Independent School District, ID.

    The career activities guide in science, part of an Idaho State Department of Vocational Education career exploration series for grades 7, 8, and 9, is designed as supplementary material to enrich the regular curriculum. Any one activity in the guide might be used without involving any other activities. The cross-referenced index indicates grades,…

  16. Classroom Activities and Demonstrations for Use in Behavioral Science Courses.

    ERIC Educational Resources Information Center

    Cology, Lorry J.

    This compilation provides descriptions of and resource materials for 25 classroom activities or demonstrations for behavioral science courses. For each activity, the following information is provided: subject area, source, time required and materials needed. In addition, discussion questions and comments on the value and use of the activities are…

  17. Early Adolescence: Active Science for Middle Schoolers.

    ERIC Educational Resources Information Center

    Padilla, Michael; Griffin, Nancy

    1980-01-01

    Describes activities appropriate for involving middle school students as active participants in the learning process. Topics discussed include archaeology, bulletin boards, dramatizations, physics experiments using the human body, oceanography, and ecology. (CS)

  18. The Effect of Physical Activity on Science Competence and Attitude towards Science Content

    ERIC Educational Resources Information Center

    Klinkenborg, Ann Maria

    2011-01-01

    This study examines the effect of physical activity on science instruction. To combat the implications of physical inactivity, schools need to be willing to consider all possible opportunities for students to engage in moderate-to-vigorous physical activity (MVPA). Integrating physical activity with traditional classroom content is one…

  19. Attention Science Teachers: Classroom Activities with Water.

    ERIC Educational Resources Information Center

    HAZWRAP, The Hazardous Waste Remedial Actions Program.

    This collection of 10 activities is designed to give students a better grasp of concepts relating to groundwater, aquifers, and hydrology. Activities can be conducted as a demonstration (especially for younger students) or as a laboratory activity for students in higher grades. The guide contains an introduction for teachers and students, a…

  20. Acid Rain: Activities for Science Teachers.

    ERIC Educational Resources Information Center

    Johnson, Eric; And Others

    1983-01-01

    Seven complete secondary/college level acid rain activities are provided. Activities include overview; background information and societal implications; major concepts; student objectives; vocabulary/material lists; procedures; instructional strategies; and questions/discussion and extension suggestions. Activities consider effects of acid rain on…

  1. Board on Earth Sciences and Resources and its Activities

    NASA Technical Reports Server (NTRS)

    Schiffries, Craig M.

    1997-01-01

    The Board will provide oversight of the earth science and resource activities within the National Research Council, provide a review of research and public activities in the solid-earth sciences, and provide analyses and recommendations relevant to the supply, delivery, and associated impacts of and issues related to hydrocarbon, metallic, and non-metallic mineral resources. The Board will monitor the status of the earth sciences, assess the health of the disciplines, and identify research opportunities, and will respond to specific agency requests.

  2. Linking Mission to Learning Activities for Assurance of Learning

    ERIC Educational Resources Information Center

    Yeung, Shirley Mo-ching

    2011-01-01

    Can accreditation-related requirements and mission statements measure learning outcomes? This study focuses on triangulating accreditation-related requirements with mission statements and learning activities to learning outcomes. This topic has not been comprehensively explored in the past. After looking into the requirements of AACSB, ISO, and…

  3. The Role of Outside-School Factors in Science Education: A Two-Stage Theoretical Model Linking Bourdieu and Sen, with a Case Study

    ERIC Educational Resources Information Center

    Gokpinar, Tuba; Reiss, Michael

    2016-01-01

    The literature in science education highlights the potentially significant role of outside-school factors such as parents, cultural contexts and role models in students' formation of science attitudes and aspirations, and their attainment in science classes. In this paper, building on and linking Bourdieu's key concepts of habitus, cultural and…

  4. Crosswalk between the "Framework for K-12 Science Education" and "Standards for the 21st-Century Learner": School Librarians as the Crucial Link

    ERIC Educational Resources Information Center

    Subramaniam, Mega; Ahn, June; Waugh, Amanda; Taylor, Natalie Greene; Druin, Allison; Fleischmann, Kenneth R.; Walsh, Greg

    2013-01-01

    Within the school library community, there have been persuasive calls for school librarians to contribute to science learning. We present a conceptual framework that links national standards of science education ("Framework for K-12 Science Education: Practices, Crosscutting Concepts, and Core Ideas," referred to as…

  5. Measures of health sciences journal use: a comparison of vendor, link-resolver, and local citation statistics*

    PubMed Central

    De Groote, Sandra L.; Blecic, Deborah D.; Martin, Kristin

    2013-01-01

    Objective: Libraries require efficient and reliable methods to assess journal use. Vendors provide complete counts of articles retrieved from their platforms. However, if a journal is available on multiple platforms, several sets of statistics must be merged. Link-resolver reports merge data from all platforms into one report but only record partial use because users can access library subscriptions from other paths. Citation data are limited to publication use. Vendor, link-resolver, and local citation data were examined to determine correlation. Because link-resolver statistics are easy to obtain, the study library especially wanted to know if they correlate highly with the other measures. Methods: Vendor, link-resolver, and local citation statistics for the study institution were gathered for health sciences journals. Spearman rank-order correlation coefficients were calculated. Results: There was a high positive correlation between all three data sets, with vendor data commonly showing the highest use. However, a small percentage of titles showed anomalous results. Discussion and Conclusions: Link-resolver data correlate well with vendor and citation data, but due to anomalies, low link-resolver data would best be used to suggest titles for further evaluation using vendor data. Citation data may not be needed as it correlates highly with other measures. PMID:23646026

  6. Placebo-Activated Neural Systems are Linked to Antidepressant Responses

    PubMed Central

    Peciña, Marta; Bohnert, Amy S. B.; Sikora, Magdalena; Avery, Erich T.; Langenecker, Scott A.; Mickey, Brian J.; Zubieta, Jon-Kar

    2016-01-01

    Importance High placebo responses have been observed across a wide range of pathologies, severely impacting drug development. Objective Here we examined neurochemical mechanisms underlying the formation of placebo effects in patients with Major Depressive Disorder (MDD). Participants Thirty-five medication-free MDD patients. Design and Intervention We performed a single-blinded two-week cross-over randomized controlled trial of two identical oral placebos (described as having either “active” or “inactive” fast-acting antidepressant-like effects) followed by a 10-week open-label treatment with a selective serotonin reuptake inhibitor (SSRI) or in some cases, another agent as clinically indicated. The volunteers were studied with PET and the μ-opioid receptor (MOR)-selective radiotracer [11C]carfentanil after each 1-week “inactive” and “active” oral placebo treatment. In addition, 1 mL of isotonic saline was administered intravenously (i.v.) within sight of the volunteer during PET scanning every 4 min over 20 min only after the 1-week active placebo treatment, with instructions that the compound may be associated with the activation of brain systems involved in mood improvement. This challenge stimulus was utilized to test the individual capacity to acutely activate endogenous opioid neurotransmision under expectations of antidepressant effect. Setting A University Health System. Main Outcomes and Measures Changes in depressive symptoms in response to “active” placebo and antidepressant. Baseline and activation measures of MOR binding. Results Higher baseline MOR binding in the nucleus accumbens (NAc) was associated with better response to antidepressant treatment (r=0.48; p=0.02). Reductions in depressive symptoms after 1-week of “active” placebo treatment, compared to the “inactive”, were associated with increased placebo-induced μ-opioid neurotransmission in a network of regions implicated in emotion, stress regulation, and the

  7. Controlling self-sustained spiking activity by adding or removing one network link

    NASA Astrophysics Data System (ADS)

    Xu, Kesheng; Huang, Wenwen; Li, Baowen; Dhamala, Mukesh; Liu, Zonghua

    2013-06-01

    Being able to control the neuronal spiking activity in specific brain regions is central to a treatment scheme in several brain disorders such as epileptic seizures, mental depression, and Parkinson's diseases. Here, we present an approach for controlling self-sustained oscillations by adding or removing one directed network link in coupled neuronal oscillators, in contrast to previous approaches of adding stimuli or noise. We find that such networks can exhibit a variety of activity patterns such as on-off switch, sustained spikes, and short-term spikes. We derive the condition for a specific link to be the controller of the on-off effect. A qualitative analysis is provided to facilitate the understanding of the mechanism for spiking activity by adding one link. Our findings represent the first report on generating spike activity with the addition of only one directed link to a network and provide a deeper understanding of the microscopic roots of self-sustained spiking.

  8. Conformational Stability and Catalytic Activity of PTEN Variants Linked to Cancers and Autism Spectrum Disorders

    PubMed Central

    Johnston, Sean B.; Raines, Ronald T.

    2015-01-01

    Phosphoinositides are membrane components that play critical regulatory roles in mammalian cells. The enzyme PTEN, which catalyzes the dephosphorylation of the phosphoinositide PIP3, is damaged in most sporadic tumors. Mutations in the PTEN gene have also been linked to autism spectrum disorders and other forms of delayed development. Here, human PTEN is shown to be on the cusp of unfolding under physiological conditions. Variants of human PTEN linked to somatic cancers and disorders on the autism spectrum are shown to be impaired in their conformational stability, catalytic activity, or both. Those variants linked only to autism have higher activity than those linked to cancers. PTEN-L, which is a secreted trans-active isoform, has greater conformational stability than does the wild-type enzyme. These data indicate that PTEN is a fragile enzyme cast in a crucial role in cellular metabolism, and suggest that PTEN-L is a repository for a critical catalytic activity. PMID:25647146

  9. Linking New Learning with Previous Experiences: An Activity in Teaching Dimensional Analysis.

    ERIC Educational Resources Information Center

    Schmidt, Stan M.; Werner, Jana Rae

    Throughout America's secondary science classrooms, students struggle to master fundamental science principles, especially when math-related applications are involved. For example, in chemistry students struggle to solve quantitative problems. This paper presents an activity that leads to a useful understanding of dimensional analysis; i.e., unit…

  10. Aviation Science Activities for Elementary Grades. Revised.

    ERIC Educational Resources Information Center

    Federal Aviation Administration (DOT), Washington, DC.

    This guide contains the procedures and lists of materials needed for 105 aviation activities, demonstrations, and experiments. These activities, demonstrations, and experiments (suitable for students in all elementary grades) are organized into three sections by major topic area: (1) properties of air; (2) factors related to airplane flight; and…

  11. School-Linked Prevention: Theory, Science, and Practice for Enhancing the Lives of Children and Youth

    ERIC Educational Resources Information Center

    Kenny, Maureen E.; Waldo, Michael; Warter, Elizabeth H.; Barton, Catherine

    2002-01-01

    Principles drawn from contemporary developmental-contextualism are presented as a framework for guiding the design, implementation, and evaluation of school-linked prevention programs that are consistent with an emerging body of research specifying best practices in prevention. Two school-linked preventive interventions, the Gardner Extended…

  12. Timeless links replication termination to mitotic kinase activation.

    PubMed

    Dheekollu, Jayaraju; Wiedmer, Andreas; Hayden, James; Speicher, David; Gotter, Anthony L; Yen, Tim; Lieberman, Paul M

    2011-01-01

    The mechanisms that coordinate the termination of DNA replication with progression through mitosis are not completely understood. The human Timeless protein (Tim) associates with S phase replication checkpoint proteins Claspin and Tipin, and plays an important role in maintaining replication fork stability at physical barriers, like centromeres, telomeres and ribosomal DNA repeats, as well as at termination sites. We show here that human Tim can be isolated in a complex with mitotic entry kinases CDK1, Auroras A and B, and Polo-like kinase (Plk1). Plk1 bound Tim directly and colocalized with Tim at a subset of mitotic structures in M phase. Tim depletion caused multiple mitotic defects, including the loss of sister-chromatid cohesion, loss of mitotic spindle architecture, and a failure to exit mitosis. Tim depletion caused a delay in mitotic kinase activity in vivo and in vitro, as well as a reduction in global histone H3 S10 phosphorylation during G2/M phase. Tim was also required for the recruitment of Plk1 to centromeric DNA and formation of catenated DNA structures at human centromere alpha satellite repeats. Taken together, these findings suggest that Tim coordinates mitotic kinase activation with termination of DNA replication. PMID:21573113

  13. Timeless links replication termination to mitotic kinase activation.

    PubMed

    Dheekollu, Jayaraju; Wiedmer, Andreas; Hayden, James; Speicher, David; Gotter, Anthony L; Yen, Tim; Lieberman, Paul M

    2011-05-06

    The mechanisms that coordinate the termination of DNA replication with progression through mitosis are not completely understood. The human Timeless protein (Tim) associates with S phase replication checkpoint proteins Claspin and Tipin, and plays an important role in maintaining replication fork stability at physical barriers, like centromeres, telomeres and ribosomal DNA repeats, as well as at termination sites. We show here that human Tim can be isolated in a complex with mitotic entry kinases CDK1, Auroras A and B, and Polo-like kinase (Plk1). Plk1 bound Tim directly and colocalized with Tim at a subset of mitotic structures in M phase. Tim depletion caused multiple mitotic defects, including the loss of sister-chromatid cohesion, loss of mitotic spindle architecture, and a failure to exit mitosis. Tim depletion caused a delay in mitotic kinase activity in vivo and in vitro, as well as a reduction in global histone H3 S10 phosphorylation during G2/M phase. Tim was also required for the recruitment of Plk1 to centromeric DNA and formation of catenated DNA structures at human centromere alpha satellite repeats. Taken together, these findings suggest that Tim coordinates mitotic kinase activation with termination of DNA replication.

  14. Making short-term climate forecasts useful: Linking science and action.

    PubMed

    Buizer, James; Jacobs, Katharine; Cash, David

    2016-04-26

    This paper discusses the evolution of scientific and social understanding that has led to the development of knowledge systems supporting the application of El Niño-Southern Oscillation (ENSO) forecasts, including the development of successful efforts to connect climate predictions with sectoral applications and actions "on the ground". The evolution of "boundary-spanning" activities to connect science and decisionmaking is then discussed, setting the stage for a report of outcomes from an international workshop comprised of producers, translators, and users of climate predictions. The workshop, which focused on identifying critical boundary-spanning features of successful boundary organizations, included participants from Australia, Hawaii, and the Pacific Islands, the US Pacific Northwest, and the state of Ceará in northwestern Brazil. Workshop participants agreed that boundary organizations have multiple roles including those of information broker, convenor of forums for engagement, translator of scientific information, arbiter of access to knowledge, and exemplar of adaptive behavior. Through these roles, boundary organizations will ensure the stability of the knowledge system in a changing political, economic, and climatic context. The international examples reviewed in this workshop demonstrated an interesting case of convergent evolution, where organizations that were very different in origin evolved toward similar structures and individuals engaged in them had similar experiences to share. These examples provide evidence that boundary organizations and boundary-spanners fill some social/institutional roles that are independent of culture.

  15. Making short-term climate forecasts useful: Linking science and action

    PubMed Central

    Buizer, James; Jacobs, Katharine; Cash, David

    2016-01-01

    This paper discusses the evolution of scientific and social understanding that has led to the development of knowledge systems supporting the application of El Niño-Southern Oscillation (ENSO) forecasts, including the development of successful efforts to connect climate predictions with sectoral applications and actions “on the ground”. The evolution of “boundary-spanning” activities to connect science and decisionmaking is then discussed, setting the stage for a report of outcomes from an international workshop comprised of producers, translators, and users of climate predictions. The workshop, which focused on identifying critical boundary-spanning features of successful boundary organizations, included participants from Australia, Hawaii, and the Pacific Islands, the US Pacific Northwest, and the state of Ceará in northwestern Brazil. Workshop participants agreed that boundary organizations have multiple roles including those of information broker, convenor of forums for engagement, translator of scientific information, arbiter of access to knowledge, and exemplar of adaptive behavior. Through these roles, boundary organizations will ensure the stability of the knowledge system in a changing political, economic, and climatic context. The international examples reviewed in this workshop demonstrated an interesting case of convergent evolution, where organizations that were very different in origin evolved toward similar structures and individuals engaged in them had similar experiences to share. These examples provide evidence that boundary organizations and boundary-spanners fill some social/institutional roles that are independent of culture. PMID:20133668

  16. Linking petrology and seismology at an active volcano.

    PubMed

    Saunders, Kate; Blundy, Jon; Dohmen, Ralf; Cashman, Kathy

    2012-05-25

    Many active volcanoes exhibit changes in seismicity, ground deformation, and gas emissions, which in some instances arise from magma movement in the crust before eruption. An enduring challenge in volcano monitoring is interpreting signs of unrest in terms of the causal subterranean magmatic processes. We examined over 300 zoned orthopyroxene crystals from the 1980-1986 eruption of Mount St. Helens that record pulsatory intrusions of new magma and volatiles into an existing larger reservoir before the eruption occurred. Diffusion chronometry applied to orthopyroxene crystal rims shows that episodes of magma intrusion correlate temporally with recorded seismicity, providing evidence that some seismic events are related to magma intrusion. These time scales are commensurate with monitoring signals at restless volcanoes, thus improving our ability to forecast volcanic eruptions by using petrology. PMID:22628652

  17. CNS Active O-Linked Glycopeptides that Penetrate the BBB

    NASA Astrophysics Data System (ADS)

    Jones, Evan; Polt, Robin

    2015-06-01

    Naturally occurring glycopeptides and glycoproteins play important roles in biological processes. Glycosylation is one of the most common post-translational modifications in vivo. Glycopeptides are involved in cell signaling and sorting, providing cell surface markers for recognition. From the drug design and synthesis perspective, modification of a peptide through glycosylation results in increased bioavailability and bioactivity of glycopeptides in living systems with negligible toxicity of degradation products. Glycopeptide synthesis can be accomplished through incorporation of a glycosylated amino acid in solid phase peptide synthesis (SPPS) to form the desired peptide, or via incorporation of sugar-amino acid moieties. Additionally, research indicates that glycosylation increases penetration of the blood-brain barrier (BBB) by peptides, which may lead to novel therapeutics for neurological disorders. Recent applications of glycopeptides have focused on the in vivo central nervous system effects after peripheral administration of centrally active peptides modified with various carbohydrates.

  18. Linking lake variability, climate, and human activity in Basotu, Tanzania.

    NASA Astrophysics Data System (ADS)

    Higgins, Lindsey; Westerberg, Lars-Ove; Risberg, Jan

    2016-04-01

    Lake Basotu (4.3697°S, 35.0728°E) is a crater lake in north-central Tanzania. This lake is an important source of freshwater for local people as no perennial rivers are present. Due to intensive agricultural methods and climatic factors, lake level has fluctuated greatly over time. A history of environmental variability of the past 1800 years was established using the diatom record, magnetic parameters, and carbon content from a three meter long sediment core. Fluctuations in modern lake extent (1973 - 2015) were calculated using archived Landsat images and compared to meteorological records and documents of activity around the lake to determine the greatest impacts and their consequences on this essential water resource. Variations in the paleo-record indicate that fluctuations in lake level are not abnormal, however human influence has likely increased the sensitivity of Lake Basotu to climatic fluctuations.

  19. Linking petrology and seismology at an active volcano.

    PubMed

    Saunders, Kate; Blundy, Jon; Dohmen, Ralf; Cashman, Kathy

    2012-05-25

    Many active volcanoes exhibit changes in seismicity, ground deformation, and gas emissions, which in some instances arise from magma movement in the crust before eruption. An enduring challenge in volcano monitoring is interpreting signs of unrest in terms of the causal subterranean magmatic processes. We examined over 300 zoned orthopyroxene crystals from the 1980-1986 eruption of Mount St. Helens that record pulsatory intrusions of new magma and volatiles into an existing larger reservoir before the eruption occurred. Diffusion chronometry applied to orthopyroxene crystal rims shows that episodes of magma intrusion correlate temporally with recorded seismicity, providing evidence that some seismic events are related to magma intrusion. These time scales are commensurate with monitoring signals at restless volcanoes, thus improving our ability to forecast volcanic eruptions by using petrology.

  20. Linking Science Education to the Rural Environment: Some Experiences. Report of a Mobile Field Operational Seminar.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Bangkok (Thailand). Regional Office for Education in Asia and Oceania.

    Described is a seminar designed to promote inter-country exchange of experiences on innovations in science and technology education. Countries involved include Afghanistan, India, Japan, Malaysia, Philippines, and Sri Lanka. Each country's program is described pertaining to school levels, teacher training, science teaching, in-service training,…

  1. Agricultural Education Science Activity--Nos. PS 1-6.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Agricultural Curriculum Materials Service.

    This packet contains six science learning activities that can be used in agricultural education courses. The activities cover these topics: (1) determining the effects of soil drainage on plant growth and development; (2) determining the effect of soil compaction on plant growth and development; (3) inoculating legume seeds to promote nodule…

  2. Biomass I. Science Activities in Energy [and] Teacher's Guide.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Designed for science students in fourth, fifth, and sixth grades, the activities in this unit illustrate principles and problems related to biomass as a form of energy. (The word biomass is used to describe all solid material of animal or vegetable origin from which energy may be extracted.) Twelve student activities using art, economics,…

  3. Practising Active Science with Child Refugees: A Clinical Perspective

    ERIC Educational Resources Information Center

    Perrier, Frédéric

    2004-01-01

    In this paper, pilot sessions in Rwanda and Nepal are analysed to evaluate the therapeutic benefit of active science for traumatised child refugees. The nature of the activities, choice of tools, organisation of the sessions, group size, and the role of the educators are investigated. Despite the lack of quantitative assessment, practical…

  4. Agricultural Education Science Activity--Nos. AEM 1-4.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Agricultural Curriculum Materials Service.

    This packet contains four science learning activities that can be used in agricultural education courses. The activities cover these topics: (1) determining the effect of air pressure on fluid flow; (2) how lubrication and oil viscosity affect friction; (3) determining relative strengths of wood fasteners; and (4) determining the effects of…

  5. Developing Science and Math Integrated Activities for Middle School Students

    ERIC Educational Resources Information Center

    Sherrod, Sonya Ellouise; Dwyer, Jerry; Narayan, Ratna

    2009-01-01

    This article reports the development and refinement of science and mathematics integrated activities for middle school students. The expectations of the National Council of Teachers of Mathematics that students develop an understanding of mathematics and an ability to apply it gave birth to these activities. The expectations of the National…

  6. Silent Students' Participation in a Large Active Learning Science Classroom

    ERIC Educational Resources Information Center

    Obenland, Carrie A.; Munson, Ashlyn H.; Hutchinson, John S.

    2012-01-01

    Active learning in large science classrooms furthers opportunities for students to engage in the content and in meaningful learning, yet students can still remain anonymously silent. This study aims to understand the impact of active learning on these silent students in a large General Chemistry course taught via Socratic questioning and…

  7. Agricultural Education Science Activity--Nos. SS 2-4.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Agricultural Curriculum Materials Service.

    This packet contains three science learning activities that can be used in agricultural education courses. The activities cover these topics: (1) determining the effects of soil particle size on capillary action; (2) measuring levels of eroded soil particles in streams; and (3) determining the effects of soil cover and texture on surface erosion.…

  8. Agricultural Education Science Activity--Nos. GGEB 1-2.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Agricultural Curriculum Materials Service.

    This packet contains two science learning activities that can be used in agricultural education courses. The first activity, "Using Ethanol as a Solvent," is intended to help students describe the characteristics of a solvent, to enhance student observational skills dealing with physical changes, and to demonstrate the acid or alkaline nature of…

  9. Centennial Scale Variations in Lake Productivity Linked to Solar Activity

    NASA Astrophysics Data System (ADS)

    Englebrecht, A.; Bhattacharyya, S.; Guilderson, T. P.; Ingram, L.; Byrne, R.

    2012-12-01

    Solar variations on both decadal and centennial timescales have been associated with climate phenomena (van Loon et al., 2004; Hodell et al., 2001; White et al., 1997). The energy received by the Earth at the peak of the solar cycle increases by <0.1%; so the question has remained of how this could be amplified to produce an observable climate response. Recent modeling shows that the response of the Earth's climate system to the 11-year solar cycle may be amplified through stratosphere and ocean feedbacks and has the potential to impact climate variability on a multidecadal to centennial timescales (Meehl et al., 2009). Here, we report a 1000-year record of changes in the stratigraphy and carbon isotope composition of varved lake sediment from Isla Isabela (22°N, 106°W) in the subtropical northeast Pacific. Stable carbon isotopes and carbonate stratigraphy can be used to infer surface productivity in the lake. Our analysis shows variations in primary productivity on centennial timescales and suggests that solar activity may be an important component of Pacific climate variability. A possible response during solar maxima acts to keep the eastern equatorial Pacific cooler and drier than usual, producing conditions similar to a La Niña event. In the region around Isla Isabela peak solar years were characterized by decreased surface temperatures and suppressed precipitation (Meehl et al., 2009), which enhance productivity at Isabela (Kienel et al. 2011). In the future, we plan to analyze the data using advanced time series analysis techniques like the wavelets together with techniques to handle irregularly spaced time series data. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344. LLNL-ABS-571672

  10. Bridging the gap between marine biogeochemical and fisheries sciences; configuring the zooplankton link

    NASA Astrophysics Data System (ADS)

    Mitra, Aditee; Castellani, Claudia; Gentleman, Wendy C.; Jónasdóttir, Sigrún H.; Flynn, Kevin J.; Bode, Antonio; Halsband, Claudia; Kuhn, Penelope; Licandro, Priscilla; Agersted, Mette D.; Calbet, Albert; Lindeque, Penelope K.; Koppelmann, Rolf; Møller, Eva F.; Gislason, Astthor; Nielsen, Torkel Gissel; St. John, Michael

    2014-12-01

    Exploring climate and anthropogenic impacts on marine ecosystems requires an understanding of how trophic components interact. However, integrative end-to-end ecosystem studies (experimental and/or modelling) are rare. Experimental investigations often concentrate on a particular group or individual species within a trophic level, while tropho-dynamic field studies typically employ either a bottom-up approach concentrating on the phytoplankton community or a top-down approach concentrating on the fish community. Likewise the emphasis within modelling studies is usually placed upon phytoplankton-dominated biogeochemistry or on aspects of fisheries regulation. In consequence the roles of zooplankton communities (protists and metazoans) linking phytoplankton and fish communities are typically under-represented if not (especially in fisheries models) ignored. Where represented in ecosystem models, zooplankton are usually incorporated in an extremely simplistic fashion, using empirical descriptions merging various interacting physiological functions governing zooplankton growth and development, and thence ignoring physiological feedback mechanisms. Here we demonstrate, within a modelled plankton food-web system, how trophic dynamics are sensitive to small changes in parameter values describing zooplankton vital rates and thus the importance of using appropriate zooplankton descriptors. Through a comprehensive review, we reveal the mismatch between empirical understanding and modelling activities identifying important issues that warrant further experimental and modelling investigation. These include: food selectivity, kinetics of prey consumption and interactions with assimilation and growth, form of voided material, mortality rates at different age-stages relative to prior nutrient history. In particular there is a need for dynamic data series in which predator and prey of known nutrient history are studied interacting under varied pH and temperature regimes.

  11. Ocean Planet. Interdisciplinary Marine Science Activities.

    ERIC Educational Resources Information Center

    Branca, Barbara

    The Ocean Planet is a traveling exhibition from the Smithsonian Institution designed to share with the public what recent research has revealed about the oceans and to encourage ocean conservation. This booklet of lessons and activities adapts several themes from the exhibition for use in middle and high school classrooms. Lesson plans include:…

  12. Activity Based Astronomy for Primary Science Programs.

    ERIC Educational Resources Information Center

    Ginns, Ian

    Print materials in astronomy such as books, journals, charts, and posters are typically the sources of information for teachers and children about the moon, the sun, lunar and solar eclipses, planetary sizes, distances of planets from the sun, planetary atmospheres, and so on. This paper describes and analyzes a number of activities designed to…

  13. Enrichment of Data Publications in Earth Sciences - Data Reports as a Missing Link

    NASA Astrophysics Data System (ADS)

    Elger, Kirsten; Bertelmann, Roland; Haberland, Christian; Evans, Peter L.

    2015-04-01

    During the past decade, the relevance of research data stewardship has been rising significantly. Preservation and publication of scientific data for long-term use, including the storage in adequate repositories has been identified as a key issue by the scientific community as well as by bodies like research agencies. Essential for any kind of re-use is a proper description of the datasets. As a result of the increasing interest, data repositories have been developed and the included research data is accompanied with at least a minimum set of metadata. This metadata is useful for data discovery and a first insight to the content of a dataset. But often data re-use needs more and extended information. Many datasets are accompanied by a small 'readme file' with basic information on the data structure, or other accompanying documents. A source of additional information could be an article published in one of the newly emerging data journals (e.g. Copernicus's ESSD Earth System Science Data or Nature's Scientific Data). Obviously there is an information gap between a 'readme file', that is only accessible after data download (which often leads to less usage of published datasets than if the information was available beforehand) and the much larger effort to prepare an article for a peer-reviewed data journal. For many years, GFZ German Research Centre for Geosciences publishes 'Scientific Technical Reports (STR)' as a report series which is electronically persistently available and citable with assigned DOIs. This series was opened for the description of parallel published datasets as 'STR Data'. These are internally reviewed and offer a flexible publication format describing published data in depth, suitable for different datasets ranging from long-term monitoring time series of observatories to field data, to (meta-)databases, and software publications. STR Data offer a full and consistent overview and description to all relevant parameters of a linked published

  14. Providing the Missing Link: the Exposure Science Ontology ExO

    EPA Science Inventory

    Although knowledge-discovery tools are new to the exposure science community, these tools are critical for leveraging exposure information to design health studies and interpret results for improved public health decisions. Standardized ontologies define relationships, allow for ...

  15. How-to-Do-It: Linking Community Resources with the School Science Program.

    ERIC Educational Resources Information Center

    Hoots, Rita A.

    1988-01-01

    Described is a project designed to determine the kinds and types of science laboratories located in and around Yolo County, California. Summarized are some of the sites visited by the investigator and some of the impressions of those facilities. (CW)

  16. Internet Links for Science Education: Student-Scientist Partnerships (edited by Karen Cohen)

    NASA Astrophysics Data System (ADS)

    Barden, Linda M.

    1998-10-01

    Plenum: New York, 1997. xx + 260 pp. Figs., tables, photos. 15 x 22.8 cm. ISBN 0-306-45558-7. $27.50. Science education is undergoing an upheaval more fundamental than the one that occurred in the aftermath of Sputnik. Research during the past 40 years has led to a radical change in the way we view children's learning of science. The National Science Education Standards (NSES) suggest a new model for teaching science based upon these research findings. Societal changes, particularly changes in business, have put pressure on schools to alter the emphasis of curricula from rote memory and individual competition to problem solving using a variety of technological skills and teamwork/team competition. This timely book addresses all these issues by describing projects that K-12 teachers can use to achieve the goals set forth by both NSES and business. It also provides scientists with examples of how they and their coworkers might better interact with K-12 science education to encourage a more scientifically literate society. Finally, it includes suggestions for future research in science education.

  17. Board on Earth Sciences and Resources and its activities

    SciTech Connect

    1995-06-01

    The Board on Earth Sciences and Resources (BESR) coordinates, the National Research Council`s advice to the federal government on solid-earth science issues. The board identifies opportunities for advancing basic research and understanding, reports on applications of earth sciences in such areas as disaster mitigation and resource utilization, and analyzes the scientific underpinnings and credibility of earth science information for resource, environmental and other applications and policy decision. Committees operating under the guidance of the Board conducts studies addressing specific issues within the earth sciences. The current committees are as follows: Committee on Geophysical and Environmental Data; Mapping Sciences Committee; Committee on Seismology; Committee on Geodesy; Rediscovering Geography Committee; Committee on Research Programs of the US Bureau of Mines. The following recent reports are briefly described: research programs of the US Bureau of Mines, first assessment 1994; Mount Rainier, active cascade volcano; the national geomagnetic initiative; reservoir class field demonstration program; solid-earth sciences and society; data foundation for the national spatial infrastructure; promoting the national spatial data infrastructure through partnerships; toward a coordinated spatial data infrastructure for the nation; and charting a course into the digital era; guidance to the NOAA`s nautical charting mission.

  18. Developmental Benefits of Extracurricular Involvement: Do Peer Characteristics Mediate the Link between Activities and Youth Outcomes?

    ERIC Educational Resources Information Center

    Fredricks, Jennifer A.; Eccles, Jacquelynn S.

    2005-01-01

    In this article, we test: (a) the relation between school-based extracurricular participation and indicators of positive and negative development across a range of activity contexts, and (b) a mediation model linking activity participation, prosocial peers, and development. Extensive survey information was collected from a predominately White…

  19. Science Support: The Building Blocks of Active Data Curation

    NASA Astrophysics Data System (ADS)

    Guillory, A.

    2013-12-01

    While the scientific method is built on reproducibility and transparency, and results are published in peer reviewed literature, we have come to the digital age of very large datasets (now of the order of petabytes and soon exabytes) which cannot be published in the traditional way. To preserve reproducibility and transparency, active curation is necessary to keep and protect the information in the long term, and 'science support' activities provide the building blocks for active data curation. With the explosive growth of data in all fields in recent years, there is a pressing urge for data centres to now provide adequate services to ensure long-term preservation and digital curation of project data outputs, however complex those may be. Science support provides advice and support to science projects on data and information management, from file formats through to general data management awareness. Another purpose of science support is to raise awareness in the science community of data and metadata standards and best practice, engendering a culture where data outputs are seen as valued assets. At the heart of Science support is the Data Management Plan (DMP) which sets out a coherent approach to data issues pertaining to the data generating project. It provides an agreed record of the data management needs and issues within the project. The DMP is agreed upon with project investigators to ensure that a high quality documented data archive is created. It includes conditions of use and deposit to clearly express the ownership, responsibilities and rights associated with the data. Project specific needs are also identified for data processing, visualization tools and data sharing services. As part of the National Centre for Atmospheric Science (NCAS) and National Centre for Earth Observation (NCEO), the Centre for Environmental Data Archival (CEDA) fulfills this science support role of facilitating atmospheric and Earth observation data generating projects to ensure

  20. What Preparatory Science is Needed in Coronal Structure and Activity

    NASA Technical Reports Server (NTRS)

    Antiochos, S. K.

    2011-01-01

    Solar Orbiter and Solar Probe Plus will launch in six short years! Before then, we need to accomplish a great deal of science in order to be able to maximize the return of these missions. Preparatory science is especially important for exploratory missions such as SO and SPP, because they truly will be going "where no mission has gone before". Such preparatory science may include all types of research: theory, modeling, data exploitation, and supporting observations. This meeting provides an opportunity for the community to define and begin this critical preparatory work. In this talk I will provide an overview of our state of knowledge in coronal structure and activity, describe what I believe are the most promising opportunities for advances by SO and SPP, and lead a discussion on what programs need to be implemented now in order to achieve these science advances by the time SO and SPP launch.

  1. Translation of science to surgery: linking emerging concepts in biological cartilage repair to surgical intervention.

    PubMed

    Moran, C J; Shannon, F J; Barry, F P; O'Byrne, J M; O'Brien, T; Curtin, W

    2010-09-01

    Orthopaedic surgery is in an exciting transitional period as modern surgical interventions, implants and scientific developments are providing new therapeutic options. As advances in basic science and technology improve our understanding of the pathology and repair of musculoskeletal tissue, traditional operations may be replaced by newer, less invasive procedures which are more appropriately targeted at the underlying pathophysiology. However, evidence-based practice will remain a basic requirement of care. Orthopaedic surgeons can and should remain at the forefront of the development of novel therapeutic interventions and their application. Progression of the potential of bench research into an improved array of orthopaedic treatments in an effective yet safe manner will require the development of a subgroup of specialists with extended training in research to play an important role in bridging the gap between laboratory science and clinical practice. International regulations regarding the introduction of new biological treatments will place an additional burden on the mechanisms of this translational process, and orthopaedic surgeons who are trained in science, surgery and the regulatory environment will be essential. Training and supporting individuals with these skills requires special consideration and discussion by the orthopaedic community. In this paper we review some traditional approaches to the integration of orthopaedic science and surgery, the therapeutic potential of current regenerative biomedical science for cartilage repair and ways in which we may develop surgeons with the skills required to translate scientific discovery into effective and properly assessed orthopaedic treatments.

  2. Science Art: Projects and Activities That Teach Science Concepts and Develop Process Skills. Grades 2-4.

    ERIC Educational Resources Information Center

    Schecter, Deborah

    The activities in this collection are designed to help teachers bring the worlds of science and art into the classroom. Each activity is both a hands-on science investigation and an art experience. As students create satisfying art projects, they utilize science skills such as observing, predicting, investigating, and communicating. The projects…

  3. Collaborative activities for improving the quality of science teaching and learning and learning to teach science

    NASA Astrophysics Data System (ADS)

    Tobin, Kenneth

    2012-03-01

    I have been involved in research on collaborative activities for improving the quality of teaching and learning high school science. Initially the collaborative activities we researched involved the uses of coteaching and cogenerative dialogue in urban middle and high schools in Philadelphia and New York (currently I have active research sites in New York and Brisbane, Australia). The research not only transformed practices but also produced theories that informed the development of additional collaborative activities and served as interventions for research and creation of heuristics for professional development programs and teacher certification courses. The presentation describes a collage of collaborative approaches to teaching and learning science, including coteaching, cogenerative dialogue, radical listening, critical reflection, and mindful action. For each activity in the collage I provide theoretical frameworks and empirical support, ongoing research, and priorities for the road ahead. I also address methodologies used in the research, illustrating how teachers and students collaborated as researchers in multilevel investigations of teaching and learning and learning to teach that included ethnography, video analysis, and sophisticated analyses of the voice, facial expression of emotion, eye gaze, and movement of the body during classroom interactions. I trace the evolution of studies of face-to-face interactions in science classes to the current focus on emotions and physiological aspects of teaching and learning (e.g., pulse rate, pulse strength, breathing patterns) that relate to science participation and achievement.

  4. Enabling the Future: Linking Science and Technology to Societal Goals. A Report.

    ERIC Educational Resources Information Center

    Carnegie Commission on Science, Technology, and Government, New York, NY.

    This report seeks ways to improve the knowledge, understanding, and information available to the federal government on the long-term nature of the science and technology (S&T) enterprise as it relates to societal goals. The recommendations focus on a few key issues: improving the national capacity to define and revise long-term S&T goals; linking…

  5. Combustion and Energy Transfer Experiments: A Laboratory Model for Linking Core Concepts across the Science Curriculum

    ERIC Educational Resources Information Center

    Barreto, Jose C.; Dubetz, Terry A.; Schmidt, Diane L.; Isern, Sharon; Beatty, Thomas; Brown, David W.; Gillman, Edward; Alberte, Randall S.; Egiebor, Nosa O.

    2007-01-01

    Core concepts can be integrated throughout lower-division science and engineering courses by using a series of related, cross-referenced laboratory experiments. Starting with butane combustion in chemistry, the authors expanded the underlying core concepts of energy transfer into laboratories designed for biology, physics, and engineering. This…

  6. Linking Environmental Science Students to External Community Partners: A Critical Assessment of a Service Learning Course

    ERIC Educational Resources Information Center

    Grossman, Julie; Cooper, Terrence

    2004-01-01

    This article describes a course that integrates environmental science students into local community organizations. Despite initially high expectations, students who completed the course held negative opinions about their experience because of inadequate community partner preparation. Based on the course's successes and challenges, in this article,…

  7. Teaching an Integrated Science Curriculum: Linking Teacher Knowledge and Teaching Assignments

    ERIC Educational Resources Information Center

    Harrell, Pamela Esprivalo

    2010-01-01

    A number of factors affect successful implementation of an integrated science curriculum, including various outputs and inputs related to teacher quality such as professional development experiences, adequate planning periods, and adequate content preparation of teachers with regard to content knowledge associated with the curriculum taught. This…

  8. Introduction: Why Link Indigenous Ways of Knowing with the Teaching of Environmental Studies and Sciences?

    ERIC Educational Resources Information Center

    Rich, Nancy

    2012-01-01

    This paper introduces a mini-symposium on bringing Indigenous ways of knowing together with the teaching of environmental studies and sciences (ESS). Both knowledges share a fundamental interest in the relationship of humans with the Earth, yet until recently, Indigenous ways of knowing have rarely been visible in the teaching of ESS. Teaching…

  9. Promoting Technology-Assisted Active Learning in Computer Science Education

    ERIC Educational Resources Information Center

    Gao, Jinzhu; Hargis, Jace

    2010-01-01

    This paper describes specific active learning strategies for teaching computer science, integrating both instructional technologies and non-technology-based strategies shown to be effective in the literature. The theoretical learning components addressed include an intentional method to help students build metacognitive abilities, as well as…

  10. Independent Learning Activities in Science for Students At-Risk.

    ERIC Educational Resources Information Center

    Geiger, Emily

    The purpose of this project was to determine whether third grade students, given written directions and necessary materials, could work without teacher direction for 30 minutes. Students (N=25) were to gain skill and confidence in carrying out the processes required for completing an independent learning activity by completing science learning…

  11. Microgravity: Teacher's Guide with Activities for Physical Science.

    ERIC Educational Resources Information Center

    Vogt, Gregory L.; Wargo, Michael J.

    This teacher's guide to microgravity contains 16 student science activities with full background information to facilitate an understanding of the concepts of microgravity for teachers and students. Topics covered in the background sections include the definitions of gravity and microgravity, creating microgravity, the fluid state, combustion…

  12. Learning Activity Package, Physical Science 92, LAPs 1-9.

    ERIC Educational Resources Information Center

    Williams, G. J.

    This set of nine teacher-prepared Learning Activity Packages (LAPs) for individualized instruction in physical science covers the topics of scientific equipment and procedures; measure of time, length, area, and volume; water; oxygen and oxidation; atmospheric pressure; motion; machines; carbon; and light and sound. Each unit contains a rationale…

  13. Earth Science Big Data Activities at Research Data Alliance

    NASA Astrophysics Data System (ADS)

    Kuo, Kwo-Sen; Baumann, Peter; Evans, Ben; Riedel, Morris

    2016-04-01

    In this presentation we introduce Earth science related activities of the Big Data Interest Group (BDIG) in Research Data Alliance (RDA). "RDA is an international organization focused on the development of infrastructure and community activities that reduce barriers to data sharing and exchange, and the acceleration of data driven innovation worldwide." The participation of researchers in RDA is voluntary. As the name implies, an Interest Group is a collection of participants sharing the same interest. The BDIG seeks to address community needs on all things having to do with Big Data. The ultimate goal of RDA Big Data Interest Group is to produce a set of recommendation documents to advise diverse research communities with respect to: • How to select an appropriate Big Data solution for a particular science application to realize optimal value? and • What are the best practices in dealing with various data and computing issues associated with such a solution? The primary means to reaching such recommendations is through the establishment and work of Working Groups, each of which focuses on a specific issue. Although BDIG is not specific to Earth science, its recent activities revolve mostly around it. We introduce some of these activities that are designed to advance our knowledge and to characterize Big Data in Earth science.

  14. Active Classroom Participation in a Group Scribbles Primary Science Classroom

    ERIC Educational Resources Information Center

    Chen, Wenli; Looi, Chee-Kit

    2011-01-01

    A key stimulus of learning efficacy for students in the classroom is active participation and engagement in the learning process. This study examines the nature of teacher-student and student-student discourse when leveraged by an interactive technology--Group Scribbles (GS) in a Primary 5 Science classroom in Singapore which supports rapid…

  15. Science on the Web: Web Activities Using Scientific Data.

    ERIC Educational Resources Information Center

    Poppe, Barbara; McAlister, Deborah; Richardson, Lisa

    This guide is intended to help teachers learn about using special software tools for the World Wide Web. It makes use of the scientific data produced by the National Oceanic and Atmospheric Administration (NOAA) and other government agencies. Activities in this booklet include: (1) "Finding People in Cyberspace"; (2) "Finding Science on the Web";…

  16. Activities in planetary geology for the physical and earth sciences

    NASA Technical Reports Server (NTRS)

    Dalli, R.; Greeley, R.

    1982-01-01

    A users guide for teaching activities in planetary geology, and for physical and earth sciences is presented. The following topics are discussed: cratering; aeolian processes; planetary atmospheres, in particular the Coriolis Effect and storm systems; photogeologic mapping of other planets, Moon provinces and stratigraphy, planets in stereo, land form mapping of Moon, Mercury and Mars, and geologic features of Mars.

  17. Developing a Repertoire of Activities for Teaching Physical Science.

    ERIC Educational Resources Information Center

    Cain, Peggy W.

    This activity manual is divided into 15 units which focus on: the nature of science; metric measurements; properties of matter; energy; atomic structure; chemical reactions; acids, bases, and salts; temperature and heat; readioactivity; mechanics; wave motion, sound, and light; static charges and current electricity magnetism and electromagnetism;…

  18. Solar energy education. Renewable energy activities for general science

    SciTech Connect

    Not Available

    1985-01-01

    Renewable energy topics are integrated with the study of general science. The literature is provided in the form of a teaching manual and includes such topics as passive solar homes, siting a home for solar energy, and wind power for the home. Other energy topics are explored through library research activities. (BCS)

  19. Scientific and administrative activities at the Lunar Science Institute

    NASA Technical Reports Server (NTRS)

    1974-01-01

    The scientific and administrative activities of the Lunar Science Institute during the period 15 July through 31 December 1973 are reported. The subjects discussed are: (1) contributions of the organization, (2) organization of the staff, (3) administration functions, and (4) scientific and professional meetings held at the institute.

  20. Earth Science Activities: A Guide to Effective Elementary School Science Teaching.

    ERIC Educational Resources Information Center

    Kanis, Ira B.; Yasso, Warren E.

    The primary emphasis of this book is on new or revised earth science activities that promote concept development rather than mere verification of concepts learned by passive means. Chapter 2 describes philosophies, strategies, methods, and techniques to guide preservice and inservice teachers, school building administrators, and curriculum…

  1. Social Activism in Elementary Science Education: A Science, Technology, and Society Approach to Teach Global Warming

    ERIC Educational Resources Information Center

    Lester, Benjamin T.; Ma, Li; Lee, Okhee; Lambert, Julie

    2006-01-01

    As part of a large-scale instructional intervention research, this study examined elementary students' science knowledge and awareness of social activism with regard to an increased greenhouse effect and global warming. The study involved fifth-grade students from five elementary schools of varying demographic makeup in a large urban school…

  2. 101 Environmental Education Activities. Booklet 5--Science & Social Studies (Interdisciplinary) Activities.

    ERIC Educational Resources Information Center

    Whitney, Helen, Comp.

    Forestry is the main focus of this fifth booklet in the series "101 Environmental Education Activities" by the Upper Mississippi River ECO-Center. Designed for students in the intermediate grades and junior high school, the booklet contains 9 science and social studies activities and 5 interdisciplinary activities. Most activity descriptions…

  3. Board on Earth Sciences and Resources and its activities

    SciTech Connect

    de Souza, Dr. Anthony R.

    2000-02-23

    This 1999 annual report of the activities of the National Research Council's (NRC) Board on Earth Sciences and Resources (BESR) begins with an introduction to the Board. This report (1) lists activities of the Board sustained by Department of Energy support, (2) presents accomplishments of the Board, (3) describes current and proposed studies of the Board, and (4) provides a brief review of the Board's future plans.

  4. Exploring the Solar System Activities Outline: Hands-On Planetary Science for Formal Education K-14 and Informal Settings

    NASA Technical Reports Server (NTRS)

    Allen, J. S.; Tobola, K. W.; Lindstrom, M. L.

    2003-01-01

    Activities by NASA scientists and teachers focus on integrating Planetary Science activities with existing Earth science, math, and language arts curriculum. The wealth of activities that highlight missions and research pertaining to the exploring the solar system allows educators to choose activities that fit a particular concept or theme within their curriculum. Most of the activities use simple, inexpensive techniques that help students understand the how and why of what scientists are learning about comets, asteroids, meteorites, moons and planets. With these NASA developed activities students experience recent mission information about our solar system such as Mars geology and the search for life using Mars meteorites and robotic data. The Johnson Space Center ARES Education team has compiled a variety of NASA solar system activities to produce an annotated thematic outline useful to classroom educators and informal educators as they teach space science. An important aspect of the outline annotation is that it highlights appropriate science content information and key science and math concepts so educators can easily identify activities that will enhance curriculum development. The outline contains URLs for the activities and NASA educator guides as well as links to NASA mission science and technology. In the informal setting educators can use solar system exploration activities to reinforce learning in association with thematic displays, planetarium programs, youth group gatherings, or community events. Within formal education at the primary level some of the activities are appropriately designed to excite interest and arouse curiosity. Middle school educators will find activities that enhance thematic science and encourage students to think about the scientific process of investigation. Some of the activities offered are appropriate for the upper levels of high school and early college in that they require students to use and analyze data.

  5. Ready to put metadata on the post-2015 development agenda? Linking data publications to responsible innovation and science diplomacy.

    PubMed

    Özdemir, Vural; Kolker, Eugene; Hotez, Peter J; Mohin, Sophie; Prainsack, Barbara; Wynne, Brian; Vayena, Effy; Coşkun, Yavuz; Dereli, Türkay; Huzair, Farah; Borda-Rodriguez, Alexander; Bragazzi, Nicola Luigi; Faris, Jack; Ramesar, Raj; Wonkam, Ambroise; Dandara, Collet; Nair, Bipin; Llerena, Adrián; Kılıç, Koray; Jain, Rekha; Reddy, Panga Jaipal; Gollapalli, Kishore; Srivastava, Sanjeeva; Kickbusch, Ilona

    2014-01-01

    Metadata refer to descriptions about data or as some put it, "data about data." Metadata capture what happens on the backstage of science, on the trajectory from study conception, design, funding, implementation, and analysis to reporting. Definitions of metadata vary, but they can include the context information surrounding the practice of science, or data generated as one uses a technology, including transactional information about the user. As the pursuit of knowledge broadens in the 21(st) century from traditional "science of whats" (data) to include "science of hows" (metadata), we analyze the ways in which metadata serve as a catalyst for responsible and open innovation, and by extension, science diplomacy. In 2015, the United Nations Millennium Development Goals (MDGs) will formally come to an end. Therefore, we propose that metadata, as an ingredient of responsible innovation, can help achieve the Sustainable Development Goals (SDGs) on the post-2015 agenda. Such responsible innovation, as a collective learning process, has become a key component, for example, of the European Union's 80 billion Euro Horizon 2020 R&D Program from 2014-2020. Looking ahead, OMICS: A Journal of Integrative Biology, is launching an initiative for a multi-omics metadata checklist that is flexible yet comprehensive, and will enable more complete utilization of single and multi-omics data sets through data harmonization and greater visibility and accessibility. The generation of metadata that shed light on how omics research is carried out, by whom and under what circumstances, will create an "intervention space" for integration of science with its socio-technical context. This will go a long way to addressing responsible innovation for a fairer and more transparent society. If we believe in science, then such reflexive qualities and commitments attained by availability of omics metadata are preconditions for a robust and socially attuned science, which can then remain broadly

  6. Ready to put metadata on the post-2015 development agenda? Linking data publications to responsible innovation and science diplomacy.

    PubMed

    Özdemir, Vural; Kolker, Eugene; Hotez, Peter J; Mohin, Sophie; Prainsack, Barbara; Wynne, Brian; Vayena, Effy; Coşkun, Yavuz; Dereli, Türkay; Huzair, Farah; Borda-Rodriguez, Alexander; Bragazzi, Nicola Luigi; Faris, Jack; Ramesar, Raj; Wonkam, Ambroise; Dandara, Collet; Nair, Bipin; Llerena, Adrián; Kılıç, Koray; Jain, Rekha; Reddy, Panga Jaipal; Gollapalli, Kishore; Srivastava, Sanjeeva; Kickbusch, Ilona

    2014-01-01

    Metadata refer to descriptions about data or as some put it, "data about data." Metadata capture what happens on the backstage of science, on the trajectory from study conception, design, funding, implementation, and analysis to reporting. Definitions of metadata vary, but they can include the context information surrounding the practice of science, or data generated as one uses a technology, including transactional information about the user. As the pursuit of knowledge broadens in the 21(st) century from traditional "science of whats" (data) to include "science of hows" (metadata), we analyze the ways in which metadata serve as a catalyst for responsible and open innovation, and by extension, science diplomacy. In 2015, the United Nations Millennium Development Goals (MDGs) will formally come to an end. Therefore, we propose that metadata, as an ingredient of responsible innovation, can help achieve the Sustainable Development Goals (SDGs) on the post-2015 agenda. Such responsible innovation, as a collective learning process, has become a key component, for example, of the European Union's 80 billion Euro Horizon 2020 R&D Program from 2014-2020. Looking ahead, OMICS: A Journal of Integrative Biology, is launching an initiative for a multi-omics metadata checklist that is flexible yet comprehensive, and will enable more complete utilization of single and multi-omics data sets through data harmonization and greater visibility and accessibility. The generation of metadata that shed light on how omics research is carried out, by whom and under what circumstances, will create an "intervention space" for integration of science with its socio-technical context. This will go a long way to addressing responsible innovation for a fairer and more transparent society. If we believe in science, then such reflexive qualities and commitments attained by availability of omics metadata are preconditions for a robust and socially attuned science, which can then remain broadly

  7. Subsidence and Collapse Activity in Arabia Terra, Mars: Which Link with Magmatic Activity?

    NASA Astrophysics Data System (ADS)

    Mangold, N.; Howard, A. D.

    2014-12-01

    Collapsed terrains have been observed using Viking images in the northern part of Arabia Terra from Ismenius Lacus to Deuteronilus Mensae. Recent interpretations of some of these depressions as explosive volcanoes (Michalski and Bleacher, 2013) have renewed the interest for this region. However, recent observations also show the discovery in this region of a series of outflow channels named Okavango Valles (Mangold and Howard, 2013). These channels formed in the Hesperian through catastrophic flows having deposited sediments as deltas in ephemeral lakes. The source area of these channels takes place in a region of widespread depressions and local collapse pits. A continuum of landforms exists from broad depressions (~100 km in length and 100s m in depth) and sharper collapse structures (<100 km in diameter). Given the link between these depressions and the presence of outflow channels, we interpret the collapse structures as resulting from a specific lithology with volatile-rich sediments (or megaregolith) buried at depth. Collapse may be due either to the melting of subsurface ice, or subsurface flows triggered by a change in the groundwater table, or the (less likely) dissolution of buried chemical sediments. Magmatic activity is not excluded: a regionally enhanced thermal flux during the Hesperian could have triggered ground ice melting, and could have initiated subsidence subsequently, but explosive volcanism at the surface is not necessary to explain the presence of large collapsed terrains. Michalski, J. and J. Bleacher, 2013. Supervolcanoes within an ancient volcanic province in Arabia Terra, Mars, Nature, doi:10.1038/nature12482 Mangold N., and A. D. Howard, 2013. Outflow channels with deltaic deposits in Ismenius Lacus, Mars, Icarus, doi.org/10.1016/j.icarus.2013.05.040

  8. Science Activities for Teachers and Families To Explore with Young Children.

    ERIC Educational Resources Information Center

    Abdi, S. Wali; Freilich, Mark B.; Taylor, Satomi Izumi

    1998-01-01

    Describes science activities for preschool through primary-grade children, focusing on goals of science education, science processes, and characteristics of high-quality science activities. Notes that hands-on activities explore scientific concepts such as volume, gravity, heat conductivity, and condensation. (KB)

  9. On the Faceting and Linking of PROV for Earth Science Data Systems

    NASA Astrophysics Data System (ADS)

    Hua, H.; Manipon, G.; Wilson, B. D.; Tan, D.; Starch, M.

    2015-12-01

    Faceted search has yielded powerful capabilities for discovery of information by applying multiple filters to explore information. This is often more effective when the information is decomposed into faceted components that can be sliced and diced during faceted navigation. We apply this approach to the representation of PROV for Earth Science (PROV-ES) to facilitate more atomic units of provenance for discovery. Traditional bundles of PROV are then decomposed to enable finer-grain discovery of provenance. Linkages across provenance components can then be explored across seemingly disparate bundles. We will show how mappings into this provenance approach can be used to explore more data life-cycle relationships from observation to data to findings. We will also show examples of how this approach can be used to improve the discovery, access, and transparency of NASA datasets and the science data systems that were used to capture, manage, and produce the provenance information.

  10. Learning Activities That Combine Science Magic Activities with the 5E Instructional Model to Influence Secondary-School Students' Attitudes to Science

    ERIC Educational Resources Information Center

    Lin, Jang-Long; Cheng, Meng-Fei; Chang, Ying-Chi; Li, Hsiao-Wen; Chang, Jih-Yuan; Lin, Deng-Min

    2014-01-01

    The purpose of this study was to investigate how learning materials based on Science Magic activities affect student attitudes to science. A quasi-experimental design was conducted to explore the combination of Science Magic with the 5E Instructional Model to develop learning materials for teaching a science unit about friction. The participants…

  11. Teachers and Students Perceptions of the Active Science Curriculum: Incorporating Physical Activity into Middle School Science Classrooms

    ERIC Educational Resources Information Center

    Finn, Kevin E.; McInnis, Kyle J.

    2014-01-01

    Many children get little to no regular physical education during the school day. National recommendations call for schools to offer physical activity as part of planned academic lessons that teach math, language arts, science, and other subjects through movement. The purpose of this study was to analyze the student and teacher perceptions of the…

  12. Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase*

    PubMed Central

    Bihan, Dominique; Bonna, Arkadiusz; Rubin, Kristofer; Farndale, Richard W.

    2016-01-01

    The hallmark of fibrotic disorders is a highly cross-linked and dense collagen matrix, a property driven by the oxidative action of lysyl oxidase. Other fibrosis-associated proteins also contribute to the final collagen matrix properties, one of which is fibromodulin. Its interactions with collagen affect collagen cross-linking, packing, and fibril diameter. We investigated the possibility that a specific relationship exists between fibromodulin and lysyl oxidase, potentially imparting a specific collagen matrix phenotype. We mapped the fibromodulin-collagen interaction sites using the collagen II and III Toolkit peptide libraries. Fibromodulin interacted with the peptides containing the known collagen cross-linking sites and the MMP-1 cleavage site in collagens I and II. Interestingly, the interaction sites are closely aligned within the quarter-staggered collagen fibril, suggesting a multivalent interaction between fibromodulin and several collagen helices. Furthermore, we detected an interaction between fibromodulin and lysyl oxidase (a major collagen cross-linking enzyme) and mapped the interaction site to 12 N-terminal amino acids on fibromodulin. This interaction also increases the activity of lysyl oxidase. Together, the data suggest a fibromodulin-modulated collagen cross-linking mechanism where fibromodulin binds to a specific part of the collagen domain and also forms a complex with lysyl oxidase, targeting the enzyme toward specific cross-linking sites. PMID:26893379

  13. Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase.

    PubMed

    Kalamajski, Sebastian; Bihan, Dominique; Bonna, Arkadiusz; Rubin, Kristofer; Farndale, Richard W

    2016-04-01

    The hallmark of fibrotic disorders is a highly cross-linked and dense collagen matrix, a property driven by the oxidative action of lysyl oxidase. Other fibrosis-associated proteins also contribute to the final collagen matrix properties, one of which is fibromodulin. Its interactions with collagen affect collagen cross-linking, packing, and fibril diameter. We investigated the possibility that a specific relationship exists between fibromodulin and lysyl oxidase, potentially imparting a specific collagen matrix phenotype. We mapped the fibromodulin-collagen interaction sites using the collagen II and III Toolkit peptide libraries. Fibromodulin interacted with the peptides containing the known collagen cross-linking sites and the MMP-1 cleavage site in collagens I and II. Interestingly, the interaction sites are closely aligned within the quarter-staggered collagen fibril, suggesting a multivalent interaction between fibromodulin and several collagen helices. Furthermore, we detected an interaction between fibromodulin and lysyl oxidase (a major collagen cross-linking enzyme) and mapped the interaction site to 12 N-terminal amino acids on fibromodulin. This interaction also increases the activity of lysyl oxidase. Together, the data suggest a fibromodulin-modulated collagen cross-linking mechanism where fibromodulin binds to a specific part of the collagen domain and also forms a complex with lysyl oxidase, targeting the enzyme toward specific cross-linking sites.

  14. Linking Obesity and Activity Level with Children's Television and Video Game Use

    ERIC Educational Resources Information Center

    Vandewater, Elizabeth A.; Shim, Mi-suk; Caplovitz, Allison G.

    2004-01-01

    This study examined the links between childhood obesity, activity participation and television and video game use in a nationally representative sample of children (N=2831) ages 1-12 using age-normed body mass index (BMI) ratings. Results indicated that while television use was not related to children's weight status, video game use was. Children…

  15. The Science-Policy Link: Stakeholder Reactions to the Uncertainties of Future Sea Level Rise

    NASA Astrophysics Data System (ADS)

    Plag, H.; Bye, B.

    2011-12-01

    Policy makers and stakeholders in the coastal zone are equally challenged by the risk of an anticipated rise of coastal Local Sea Level (LSL) as a consequence of future global warming. Many low-lying and often densely populated coastal areas are under risk of increased inundation. More than 40% of the global population is living in or near the coastal zone and this fraction is steadily increasing. A rise in LSL will increase the vulnerability of coastal infrastructure and population dramatically, with potentially devastating consequences for the global economy, society, and environment. Policy makers are faced with a trade-off between imposing today the often very high costs of coastal protection and adaptation upon national economies and leaving the costs of potential major disasters to future generations. They are in need of actionable information that provides guidance for the development of coastal zones resilient to future sea level changes. Part of this actionable information comes from risk and vulnerability assessments, which require information on future LSL changes as input. In most cases, a deterministic approach has been applied based on predictions of the plausible range of future LSL trajectories as input. However, there is little consensus in the scientific community on how these trajectories should be determined, and what the boundaries of the plausible range are. Over the last few years, many publications in Science, Nature and other peer-reviewed scientific journals have revealed a broad range of possible futures and significant epistemic uncertainties and gaps concerning LSL changes. Based on the somewhat diffuse science input, policy and decision makers have made rather different choices for mitigation and adaptation in cases such as Venice, The Netherlands, New York City, and the San Francisco Bay area. Replacing the deterministic, prediction-based approach with a statistical one that fully accounts for the uncertainties and epistemic gaps

  16. The link between inequalities in science and the scientific evaluation process

    NASA Astrophysics Data System (ADS)

    Koren, Ilan

    2016-04-01

    Unlike the "out of the box", innovative and unconventional way of thinking we would like to cultivate in our science, the academic system tends to be very conservative in the way by which it performs academic evaluations. In the case of hiring and promotion processes, the traditional way may imply the "like attracts like" rule in which the same dominant subset of the population (with respect to culture, nation and gender) preserves its hegemony on the expense of equality and diversity. Being aware of such biases is a good start. Forcing diversity in the hiring and promoting processes is even better.

  17. Synthesis, Characterization, and Antibacterial Activity of Cross-Linked Chitosan-Glutaraldehyde

    PubMed Central

    Li, Bin; Shan, Chang-Lin; Zhou, Qing; Fang, Yuan; Wang, Yang-Li; Xu, Fei; Han, Li-Rong; Ibrahim, Muhammad; Guo, Long-Biao; Xie, Guan-Lin; Sun, Guo-Chang

    2013-01-01

    This present study deals with synthesis, characterization and antibacterial activity of cross-linked chitosan-glutaraldehyde. Results from this study indicated that cross-linked chitosan-glutaraldehyde markedly inhibited the growth of antibiotic-resistant Burkholderia cepacia complex regardless of bacterial species and incubation time while bacterial growth was unaffected by solid chitosan. Furthermore, high temperature treated cross-linked chitosan-glutaraldehyde showed strong antibacterial activity against the selected strain 0901 although the inhibitory effects varied with different temperatures. In addition, physical-chemical and structural characterization revealed that the cross-linking of chitosan with glutaraldehyde resulted in a rougher surface morphology, a characteristic Fourier transform infrared (FTIR) band at 1559 cm−1, a specific X-ray diffraction peak centered at 2θ = 15°, a lower contents of carbon, hydrogen and nitrogen, and a higher stability of glucose units compared to chitosan based on scanning electron microscopic observation, FTIR spectra, X-ray diffraction pattern, as well as elemental and thermo gravimetric analysis. Overall, this study indicated that cross-linked chitosan-glutaraldehyde is promising to be developed as a new antibacterial drug. PMID:23670533

  18. Engineering design activities and conceptual change in middle school science

    NASA Astrophysics Data System (ADS)

    Schnittka, Christine G.

    The purpose of this research was to investigate the impact of engineering design classroom activities on conceptual change in science, and on attitudes toward and knowledge about engineering. Students were given a situated learning context and a rationale for learning science in an active, inquiry-based method, and worked in small collaborative groups. One eighth-grade physical science teacher and her students participated in a unit on heat transfer and thermal energy. One class served as the control while two others received variations of an engineering design treatment. Data were gathered from teacher and student entrance and exit interviews, audio recordings of student dialog during group work, video recordings and observations of all classes, pre- and posttests on science content and engineering attitudes, and artifacts and all assignments completed by students. Qualitative and quantitative data were collected concurrently, but analysis took place in two phases. Qualitative data were analyzed in an ongoing manner so that the researcher could explore emerging theories and trends as the study progressed. These results were compared to and combined with the results of the quantitative data analysis. Analysis of the data was carried out in the interpretive framework of analytic induction. Findings indicated that students overwhelmingly possessed alternative conceptions about heat transfer, thermal energy, and engineering prior to the interventions. While all three classes made statistically significant gains in their knowledge about heat and energy, students in the engineering design class with the targeted demonstrations made the most significant gains over the other two other classes. Engineering attitudes changed significantly in the two classes that received the engineering design intervention. Implications from this study can inform teachers' use of engineering design activities in science classrooms. These implications are: (1) Alternative conceptions will

  19. Extravehicular Activity/Air Traffic Control (EVA/ATC) test report. [communication links to the astronaut

    NASA Technical Reports Server (NTRS)

    Tomaro, D. J.

    1982-01-01

    During extravehicular activity (EVA), communications between the EVA astronaut and the space shuttle orbiter are maintained by means of transceiver installed in the environmental support system backpack. Onboard the orbiter, a transceiver line replaceable unit and its associated equipment performs the task of providing a communications link to the astronaut in the extravehicular activity/air traffic control (EVA/ATC) mode. Results of the acceptance tests that performed on the system designed and fabricated for EVA/ATC testing are discussed.

  20. Curriculum Development: Linking Science Education to Life. Report of a Sub-regional Workshop on Designing and Developing Innovative Science Curriculum and Instructional Materials (Bangkok, Thailand, December 8-20, 1980).

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Bangkok (Thailand). Regional Office for Education in Asia and Oceania.

    During 1979, nine National Workshops were organized in Afghanistan, India, Japan, Malaysia, Nepal, Philippines, Sri Lanka, Thailand, and Socialist Republic of Vietnam to analyze national experiences relating to the designing and developing of innovative science curriculum and instructional materials for linking science education to real-life…

  1. S.E.A. Lab. Science Experiments and Activities. Marine Science for High School Students in Chemistry, Biology and Physics.

    ERIC Educational Resources Information Center

    Hart, Kathy, Ed.

    A series of science experiments and activities designed for secondary school students taking biology, chemistry, physics, physical science or marine science courses are outlined. Each of the three major sections--chemistry, biology, and physics--addresses concepts that are generally covered in those courses but incorporates aspects of marine…

  2. Science Cognitive and Activity Preferences and Their Relationship to Present Practices in Science Instruction in Secondary Schools in Penang, Malaysia.

    ERIC Educational Resources Information Center

    Dekkers, John; Allen, Leslie R.

    Described are science cognitive and activity preferences of a sample of secondary students in Georgetown, Malaysia whose perceptions of instructional practices in science were considered. Three instruments were used to collect data. The analysis considers the mean scores and F-test results for a Science Cognitive Preference Inventory, an Activity…

  3. Analyses of space environment effects on active fiber optic links orbited aboard the LDEF

    NASA Technical Reports Server (NTRS)

    Taylor, Edward W.; Monarski, T. W.; Berry, J. N.; Sanchez, A. D.; Padden, R. J.; Chapman, S. P.

    1993-01-01

    The results of the 'Preliminary Analysis of WL Experiment no. 701, Space Environment Effects on Operating Fiber Optic Systems,' is correlated with space simulated post retrieval terrestrial studies performed on the M0004 experiment. Temperature cycling measurements were performed on the active optical data links for the purpose of assessing link signal to noise ratio and bit error rate performance some 69 months following the experiment deployment in low Earth orbit. The early results indicate a high correlation between pre-orbit, orbit, and post-orbit functionality of the first known and longest space demonstration of operating fiber optic systems.

  4. Cross-linking and modification of cytochrome c with redox-active metal complexes

    SciTech Connect

    Lukes, A.

    1991-05-02

    This thesis consists of two parts. The first part shows that a redox-active trinuclear metal cluster may be used as a cross-linking reagent for proteins. Electron transfer is observed in the protein oligomers. The second part involves labelling the cysteine residue of baker's yeast cytochrome c with chloromercuriferrocene. Chloromercuriferrocene reacts with cytochrome c in two interesting ways. Symmetrization produces two products; two proteins cross-linked with mercury and diferrocenylmercury. Simple substitution of FeHgCl onto the protein followed by the addition of a proton by electrophilic substitution affords ferrocene and the mercuric chloride modified protein. 16 refs., 3 figs.

  5. Credibility engineering in the food industry: linking science, regulation, and marketing in a corporate context.

    PubMed

    Penders, Bart; Nelis, Annemiek P

    2011-12-01

    We expand upon the notion of the "credibility cycle" through a study of credibility engineering by the food industry. Research and development (R&D) as well as marketing contribute to the credibility of the food company Unilever and its claims. Innovation encompasses the development, marketing, and sales of products. These are directed towards three distinct audiences: scientific peers, regulators, and consumers. R&D uses scientific articles to create credit for itself amongst peers and regulators. These articles are used to support health claims on products. However, R&D, regulation, and marketing are not separate realms. A single strategy of credibility engineering connects health claims to a specific public through linking that public to a health issue and a food product.

  6. Student Levels of Cognitive Development: Establishing Links between Logical Thinking Skills and Success in Earth Science

    NASA Astrophysics Data System (ADS)

    Steer, D. N.; McConnell, D. A.; Owens, K.

    2003-12-01

    Students in inquiry-based, general education Earth Science courses were found to display a wide range of logical thinking skills that are known indicators of success in science courses. The Group Assessment of Logical Thinking instrument that tests six logical operations was administered on the first day of class and near the end of the course. Such tests can be used to assess a student's overall level of cognitive development (concrete, transitional or formal) and specific logical thinking strengths or weaknesses. Results from paired pre- and post-course logical thinking tests of 393 students indicated that 25% of the incoming students were concrete, 30% were transitional and 45% were formal thinkers. Concrete and transitional thinkers were far more likely to withdraw from or fail the course when compared to their formal thinking peers (35%, 25% and 10% respectively). Differences in scores between genders were significant with 210 females testing at 30% concrete, 35% transitional and 35% formal on the pretest compared to 183 males who tested 15% concrete, 25% transitional and 60% formal. Overall logical thinking scores of students increased significantly in every inquiry-based class with lecture-based classes showing overall lower increases. Post-test data indicated that there were fewer concrete thinkers (16% female, 7% male), little change in the number of transitional thinkers (30% female, 23% male) and more formal thinkers (54% female, 70% male) toward the end of the inquiry-based course. Scores on two of the logical operations, conservation and probability, were sufficient to separate those who received a high grade (A or B in course) from those were unsuccessful (D, F or withdrew). Students who score low in conservation operations (n=46) tend to rely on intuition rather than logic when trying to understand typical Earth System concepts such as plate tectonics, atmospheric processes and climate change. Students who score low in probability skills (n=46) have

  7. Accurate similarity index based on activity and connectivity of node for link prediction

    NASA Astrophysics Data System (ADS)

    Li, Longjie; Qian, Lvjian; Wang, Xiaoping; Luo, Shishun; Chen, Xiaoyun

    2015-05-01

    Recent years have witnessed the increasing of available network data; however, much of those data is incomplete. Link prediction, which can find the missing links of a network, plays an important role in the research and analysis of complex networks. Based on the assumption that two unconnected nodes which are highly similar are very likely to have an interaction, most of the existing algorithms solve the link prediction problem by computing nodes' similarities. The fundamental requirement of those algorithms is accurate and effective similarity indices. In this paper, we propose a new similarity index, namely similarity based on activity and connectivity (SAC), which performs link prediction more accurately. To compute the similarity between two nodes, this index employs the average activity of these two nodes in their common neighborhood and the connectivities between them and their common neighbors. The higher the average activity is and the stronger the connectivities are, the more similar the two nodes are. The proposed index not only commendably distinguishes the contributions of paths but also incorporates the influence of endpoints. Therefore, it can achieve a better predicting result. To verify the performance of SAC, we conduct experiments on 10 real-world networks. Experimental results demonstrate that SAC outperforms the compared baselines.

  8. Solar Energy Education. Renewable energy activities for earth science

    SciTech Connect

    Not Available

    1980-01-01

    A teaching manual is provided to aid teachers in introducing renewable energy topics to earth science students. The main emphasis is placed on solar energy. Activities for the student include a study of the greenhouse effect, solar gain for home heating, measuring solar radiation, and the construction of a model solar still to obtain fresh water. Instructions for the construction of apparatus to demonstrate a solar still, the greenhouse effect and measurement of the altitude and azimuth of the sun are included. (BCS)

  9. Promoting Female Students' Learning Motivation towards Science by Exercising Hands-On Activities

    ERIC Educational Resources Information Center

    Wen-jin, Kuo; Chia-ju, Liu; Shi-an, Leou

    2012-01-01

    The purpose of this study is to design different hands-on science activities and investigate which activities could better promote female students' learning motivation towards science. This study conducted three types of science activities which contains nine hands-on activities, an experience scale and a learning motivation scale for data…

  10. Intramembrane Proton Binding Site Linked to Activation of Bacterial Pentameric Ion Channel*

    PubMed Central

    Wang, Hai-Long; Cheng, Xiaolin; Sine, Steven M.

    2012-01-01

    Prokaryotic orthologs of eukaryotic Cys-loop receptor channels recently emerged as structural and mechanistic surrogates to investigate this superfamily of intercellular signaling proteins. Here, we examine proton activation of the prokaryotic ortholog GLIC using patch clamp electrophysiology, mutagenesis, and molecular dynamics (MD) simulations. Whole-cell current recordings from human embryonic kidney (HEK) 293 cells expressing GLIC show half-maximal activation at pH 6, close to the pKa of histidine, implicating the three native His residues in proton sensing linked to activation. The mutation H235F abolishes proton activation, H277Y is without effect, and all nine mutations of His-127 prevent expression on the cell surface. In the GLIC crystal structure, His-235 on transmembrane (TM) α-helix 2, hydrogen bonds to the main chain carbonyl oxygen of Ile-259 on TM α-helix 3. MD simulations show that when His-235 is protonated, the hydrogen bond persists, and the channel remains in the open conformation, whereas when His-235 is deprotonated, the hydrogen bond dissociates, and the channel closes. Mutations of the proximal Tyr-263, which also links TM α-helices 2 and 3 via a hydrogen bond, alter proton sensitivity over a 1.5 pH unit range. MD simulations show that mutations of Tyr-263 alter the hydrogen bonding capacity of His-235. The overall findings show that His-235 in the TM region of GLIC is a novel proton binding site linked to channel activation. PMID:22084238

  11. Field Training Activities for Hydrologic Science in West Java, Indonesia

    NASA Astrophysics Data System (ADS)

    Agustina, C.; Fajri, P. N.; Fathoni, F.; Gusti, T. P.; Harifa, A. C.; Hendra, Y.; Hertanti, D. R.; Lusiana, N.; Rohmat, F. I.; Agouridis, C.; Fryar, A. E.; Milewski, A.; Pandjaitan, N.; Santoso, R.; Suharyanto, A.

    2013-12-01

    In hydrologic science and engineering, one challenge is establishing a common framework for discussion among workers from different disciplines. As part of the 'Building Opportunity Out of Science and Technology: Helping Hydrologic Outreach (BOOST H2O)' project, which is supported by the U.S. Department of State, nine current or recent graduate students from four Indonesian universities participated in a week of training activities during June 2013. Students had backgrounds in agricultural engineering, civil and environmental engineering, water resources engineering, natural resources management, and soil science. Professors leading the training, which was based at Bogor Agricultural University (IPB) in west Java, included an agricultural engineer, civil engineers, and geologists. Activities in surface-water hydrology included geomorphic assessment of streams (measuring slope, cross-section, and bed-clast size) and gauging stream flow (wading with top-setting rods and a current meter for a large stream, and using a bucket and stopwatch for a small stream). Groundwater-hydrology activities included measuring depth to water in wells, conducting a pumping test with an observation well, and performing vertical electrical soundings to infer hydrostratigraphy. Students also performed relatively simple water-quality measurements (temperature, electrical conductivity, pH, and alkalinity) in streams, wells, and springs. The group analyzed data with commercially-available software such as AQTESOLV for well hydraulics, freeware such as the U.S. Geological Survey alkalinity calculator, and Excel spreadsheets. Results were discussed in the context of landscape position, lithology, and land use.

  12. The role of outside-school factors in science education: a two-stage theoretical model linking Bourdieu and Sen, with a case study

    NASA Astrophysics Data System (ADS)

    Gokpinar, Tuba; Reiss, Michael

    2016-05-01

    The literature in science education highlights the potentially significant role of outside-school factors such as parents, cultural contexts and role models in students' formation of science attitudes and aspirations, and their attainment in science classes. In this paper, building on and linking Bourdieu's key concepts of habitus, cultural and social capital, and field with Sen's capability approach, we develop a model of students' science-related capability development. Our model proposes that the role of outside-school factors is twofold, first, in providing an initial set of science-related resources (i.e. habitus, cultural and social capital), and then in conversion of these resources to science-related capabilities. The model also highlights the distinction between science-related functionings (outcomes achieved by individuals) and science-related capabilities (ability to achieve desired functionings), and argues that it is necessary to consider science-related capability development in evaluating the effectiveness of science education. We then test our theoretical model with an account of three Turkish immigrant students' science-related capabilities and the role of outside-school factors in forming and extending these capabilities. We use student and parent interviews, student questionnaires and in-class observations to provide an analysis of how outside-school factors influence these students' attitudes, aspirations and attainment in science.

  13. Ocean acidification: Linking science to management solutions using the Great Barrier Reef as a case study.

    PubMed

    Albright, Rebecca; Anthony, Kenneth R N; Baird, Mark; Beeden, Roger; Byrne, Maria; Collier, Catherine; Dove, Sophie; Fabricius, Katharina; Hoegh-Guldberg, Ove; Kelly, Ryan P; Lough, Janice; Mongin, Mathieu; Munday, Philip L; Pears, Rachel J; Russell, Bayden D; Tilbrook, Bronte; Abal, Eva

    2016-11-01

    Coral reefs are one of the most vulnerable ecosystems to ocean acidification. While our understanding of the potential impacts of ocean acidification on coral reef ecosystems is growing, gaps remain that limit our ability to translate scientific knowledge into management action. To guide solution-based research, we review the current knowledge of ocean acidification impacts on coral reefs alongside management needs and priorities. We use the world's largest continuous reef system, Australia's Great Barrier Reef (GBR), as a case study. We integrate scientific knowledge gained from a variety of approaches (e.g., laboratory studies, field observations, and ecosystem modelling) and scales (e.g., cell, organism, ecosystem) that underpin a systems-level understanding of how ocean acidification is likely to impact the GBR and associated goods and services. We then discuss local and regional management options that may be effective to help mitigate the effects of ocean acidification on the GBR, with likely application to other coral reef systems. We develop a research framework for linking solution-based ocean acidification research to practical management options. The framework assists in identifying effective and cost-efficient options for supporting ecosystem resilience. The framework enables on-the-ground OA management to be the focus, while not losing sight of CO2 mitigation as the ultimate solution.

  14. Ocean acidification: Linking science to management solutions using the Great Barrier Reef as a case study.

    PubMed

    Albright, Rebecca; Anthony, Kenneth R N; Baird, Mark; Beeden, Roger; Byrne, Maria; Collier, Catherine; Dove, Sophie; Fabricius, Katharina; Hoegh-Guldberg, Ove; Kelly, Ryan P; Lough, Janice; Mongin, Mathieu; Munday, Philip L; Pears, Rachel J; Russell, Bayden D; Tilbrook, Bronte; Abal, Eva

    2016-11-01

    Coral reefs are one of the most vulnerable ecosystems to ocean acidification. While our understanding of the potential impacts of ocean acidification on coral reef ecosystems is growing, gaps remain that limit our ability to translate scientific knowledge into management action. To guide solution-based research, we review the current knowledge of ocean acidification impacts on coral reefs alongside management needs and priorities. We use the world's largest continuous reef system, Australia's Great Barrier Reef (GBR), as a case study. We integrate scientific knowledge gained from a variety of approaches (e.g., laboratory studies, field observations, and ecosystem modelling) and scales (e.g., cell, organism, ecosystem) that underpin a systems-level understanding of how ocean acidification is likely to impact the GBR and associated goods and services. We then discuss local and regional management options that may be effective to help mitigate the effects of ocean acidification on the GBR, with likely application to other coral reef systems. We develop a research framework for linking solution-based ocean acidification research to practical management options. The framework assists in identifying effective and cost-efficient options for supporting ecosystem resilience. The framework enables on-the-ground OA management to be the focus, while not losing sight of CO2 mitigation as the ultimate solution. PMID:27564868

  15. Enhancing Earth Science And IT Literacy Through Environmental Science Information Technology Activities

    NASA Astrophysics Data System (ADS)

    Cuff, K. E.; Molinaro, M.

    2004-12-01

    The Environmental Science Information Technology Activities (ESITA) program provides grades 9 and 10 students with under-represented minority backgrounds in the East San Francisco Bay Area with real-world opportunities to learn about and apply information technologies through a series of project-based activities related to environmental science. Supported by the NSF Information Technology Experiences for Students and Teachers (ITEST) program, ESITA activities engage students in the use of newly acquired information technology (IT) skills and understandings while performing air and water quality research investigations. One project that ESITA students have become involved in relates to the currently relevant issue of elevated levels of lead found in drinking waters in Washington, D.C. Students based in the Bay Area have initiated and maintained E-mail correspondence with children who attend elementary schools in the D.C. area. After receiving a thorough explanation of required sampling procedures devised by the Bay Area students, the elementary school children have sent 500 ml water samples from their homes and schools to Berkeley along with information about the locations from which the water samples were collected. These samples were then prepared for lead analysis at Lawrence Hall of Science by ESITA students, who used resulting data to perform a preliminary assessment of the geospatial distribution of lead trouble spots throughout Washington, DC. Later, ESITA student scientists will work with students from the UC Berkeley School of Public Health to develop surveys and questionnaires that generate high quality information useful with regard to assessing the impact of the current lead crisis on younger children in the Washington, D.C. area. Through the application of new understandings to current, real-world environmental problems and issues such as that related to lead, positive changes in students' attitudes towards IT and science have occurred, which accompany

  16. A performance comparison of communication links between rural hospitals and a digital health sciences library.

    PubMed Central

    D'Alessandro, M P; D'Alessandro, D M; Kash, J B; Jurca, D A; Wakefield, D S; Schallau, S J; Galvin, J R; Erkonen, W E

    1998-01-01

    BACKGROUND: Rural physicians need access to digital health sciences libraries (DHSLs) that is easy and reasonably rapid. The goal of this project was to study rural hospitals' access to a DHSL on the Internet, by comparing differing access speeds with differing costs and their acceptability for retrieving text, image, and video information in a DHSL. METHODS: DHSL system response time was measured at three different times during the day over three different types of network connections (T1, Frame Relay, Modem). Text, image, and video information was retrieved. Costs were determined for installation and operation of the different types of network connections. RESULTS: System response times were consistent at the three different testing times for each media type retrieved by each of the three network connection types. System response times for text retrieval met literature standards for all connections. Image retrieval met literature standards for T1 and Frame relay connections. No connection met literature standards for video retrieval. CONCLUSIONS: High speed access to DHSLs is preferable; Frame relay connections provide substantively similar service as T1 connections at less cost. However, access via modem to a DHSL can provide access to the majority of information--text--in a DHSL with an acceptable system response time. PMID:9803301

  17. A biological pathway linking inflammation and depression: activation of indoleamine 2,3-dioxygenase.

    PubMed

    Christmas, David M; Potokar, Jp; Davies, Simon Jc

    2011-01-01

    This article highlights the evidence linking depression to increased inflammatory drive and explores putative mechanisms for the association by reviewing both preclinical and clinical literature. The enzyme indoleamine 2,3-dioxygenase is induced by proinflammatory cytokines and may form a link between immune functioning and altered neurotransmission, which results in depression. Increased indoleamine 2,3-dioxygenase activity may cause both tryptophan depletion and increased neurotoxic metabolites of the kynurenine pathway, two alterations which have been hypothesized to cause depression. The tryptophan-kynurenine pathway is comprehensively described with a focus on the evidence linking metabolite alterations to depression. The use of immune-activated groups at high risk of depression have been used to explore these hypotheses; we focus on the studies involving chronic hepatitis C patients receiving interferon-alpha, an immune activating cytokine. Findings from this work have led to novel strategies for the future development of antidepressants including inhibition of indoleamine 2,3-dioxygenase, moderating the cytokines which activate it, or addressing other targets in the kynurenine pathway.

  18. A serendipitous discovery of antifreeze protein-specific activity in C-linked antifreeze glycoprotein analogs.

    PubMed

    Eniade, Adewale; Purushotham, Madhusudhan; Ben, Robert N; Wang, J B; Horwath, Kathleen

    2003-01-01

    Structurally diverse carbon-linked (C-linked) analogs of antifreeze glycoprotein (AFGP) have been prepared via linear or convergent solid phase synthesis. These analogs range in molecular weight from approx 1.5-4.1 KDa and do not possess the beta-D-galactose-1,3-alpha-D-N-acetylgalactosamine carbohydrate moiety or the L-threonine-L-alanine-L-alanine polypeptide backbone native to the AFGP wild-type. Despite these dramatic structural modifications, the 2.7-KDa and 4.1-KDa analogs possess antifreeze protein-specific activity as determined by recrystallization-inhibition (RI) and thermal hysteresis (TH) assays. These analogs are weaker than the wild-type in their activity, but nanoliter osmometry indicates that these compounds are binding to ice and affecting a localized freezing point depression. This is the first example of a C-linked AFGP analog that possesses TH and RI activity and suggests that the rational design and synthesis of chemically and biologically stable AFGP analogs is a feasible and worthwhile endeavor. Given the low degree of TH activity, these compounds may prove useful for the protection of cells during freezing and thawing cycles. PMID:12777711

  19. Creating a virtual community of practice to investigate legitimate peripheral participation by African American middle school girls in science activities

    NASA Astrophysics Data System (ADS)

    Edwards, Leslie D.

    How do teenage girls develop an interest in science? What kinds of opportunities can science teachers present to female students that support their engagement with learning science? I studied one aspect of this issue by focusing on ways students could use science to enhance or gain identities that they (probably) already valued. To do that I created technology-rich activities and experiences for an after school class in science and technology for middle school girls who lived in a low socio-economic urban neighborhood. These activities and experiences were designed to create a virtual community of practice whose members used science in diverse ways. Student interest was made evident in their responses to the activities. Four conclusions emerged. (1) Opportunities to learn about the lives and work of admired African American business women interested students in learning by linking it to their middle-class aspirations and their interest in things that money and status can buy. (2) Opportunities to learn about the lives and work of African American women experts in science in a classroom context where students then practiced similar kinds of actual scientific tasks engaged students in relations of legitimate peripheral participation in a virtual and diverse community of practice focused on science which was created in the after-school classes. (3) Opportunities where students used science to show off for family, friends, and supporters of the after-school program, identities they valued, interested them enough that they engaged in long-term science and technology projects that required lots of revisions. (4) In response to the opportunities presented, new and enhanced identities developed around becoming a better student or becoming some kind of scientist.

  20. Developing tools to link environmental flows science and its practice in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Eriyagma, N.; Jinapala, K.

    2014-09-01

    The term "Environmental Flows (EF)" may be defined as "the quantity, timing and quality of water flows required to sustain freshwater and estuarine ecosystems and the human livelihoods and well-being that depend on these ecosystems". It may be regarded as "water for nature" or "environmental demand" similar to crop water requirements, industrial or domestic water demand. The practice of EF is still limited to a few developed countries such as Australia, South Africa and the UK. In many developing countries EF is rarely considered in water resources planning and is often deemed "unimportant". Sri Lanka, being a developing country, is no exception to this general rule. Although the country underwent an extensive irrigation/water resources development phase during the 1960s through to the 1980s, the concept of EF was hardly considered. However, as Sri Lanka's water resources are being exploited more and more for human usage, ecologists, water practitioners and policymakers alike have realized the importance of EF in sustaining not only freshwater and estuarine ecosystems, but also their services to humans. Hence estimation of EF has been made mandatory in environmental impact assessments (EIAs) of all large development projects involving river regulation/water abstraction. Considering EF is especially vital under the rapid urbanization and infrastructure development phase that dawned after the end of the war in the North and the East of the country in 2009. This paper details simple tools (including a software package which is under development) and methods that may be used for coarse scale estimation of EF at/near monitored locations on major rivers of Sri Lanka, along with example applications to two locations on River Mahaweli. It is hoped that these tools will help bridge the gap between EF science and its practice in Sri Lanka and other developing countries.

  1. Analyzing Activities in the Course of Science Education, According to Activity Theory: The Case of Sound

    ERIC Educational Resources Information Center

    Theodoraki, Xarikleia; Plakitsi, Katerina

    2013-01-01

    In the present study, we analyze activities on the topic of sound, which are performed in the science education laboratory lessons in the third-year students of the Department of Early Childhood Education at the University of Ioannina. The analysis of the activities is based on one of the most modern learning theories of CHAT (Cultural Historical…

  2. Epigenetic Function of Activation-Induced Cytidine Deaminase and Its Link to Lymphomagenesis

    PubMed Central

    Dominguez, Pilar M.; Shaknovich, Rita

    2014-01-01

    Activation-induced cytidine deaminase (AID) is essential for somatic hypermutation and class switch recombination of immunoglobulin (Ig) genes during B cell maturation and immune response. Expression of AID is tightly regulated due to its mutagenic and recombinogenic potential, which is known to target not only Ig genes, but also non-Ig genes, contributing to lymphomagenesis. In recent years, a new epigenetic function of AID and its link to DNA demethylation came to light in several developmental systems. In this review, we summarize existing evidence linking deamination of unmodified and modified cytidine by AID to base-excision repair and mismatch repair machinery resulting in passive or active removal of DNA methylation mark, with the focus on B cell biology. We also discuss potential contribution of AID-dependent DNA hypomethylation to lymphomagenesis. PMID:25566255

  3. An Analysis of the Learning Activities Covered in the 5th Grade Science Textbooks Based on 2005 and 2013 Turkish Science Curricula

    ERIC Educational Resources Information Center

    Aydogdu, Cemil; Idin, Sahin

    2015-01-01

    The aim of this study is to analyze the learning activities covered in 5th grade elementary science textbooks which depend on 2005 and 2013 elementary science curricula. Two elementary science textbooks [which] depend on 2005 science curriculum and two elementary science textbooks [which] depend on 2013 science curriculum were researched. The…

  4. An Analysis of the Learning Activities Covered in the 5th Grade Science Textbooks Based on 2005 and 2013 Turkish Science Curricula

    ERIC Educational Resources Information Center

    Aydogdu, Cemil; Idin, Sahin

    2015-01-01

    The aim of this study is to analyze the learning activities covered in 5th grade elementary science textbooks which depend on 2005 and 2013 elementary science curricula. Two elementary science textbooks depends on 2005 science curriculum and two elementary science textbooks depend on 2013 science curriculum were researched. The study is a…

  5. The GIANT Encyclopedia of Science Activities for Children 3 to 6: More Than 600 Science Activities Written by Teachers for Teachers.

    ERIC Educational Resources Information Center

    Charner, Kathy, Ed.

    This book presents science activities developed by teachers for children ages 3-6 years old. The activities aim to develop science skills including communication, observation, estimation, measurement, cause and effect, investigation, and evaluation in children by using their curiosity as a staring point. Activities include age suggestions, address…

  6. Dendrimer-Linked Antifreeze Proteins Have Superior Activity and Thermal Recovery.

    PubMed

    Stevens, Corey A; Drori, Ran; Zalis, Shiran; Braslavsky, Ido; Davies, Peter L

    2015-09-16

    By binding to ice, antifreeze proteins (AFPs) depress the freezing point of a solution and inhibit ice recrystallization if freezing does occur. Previous work showed that the activity of an AFP was incrementally increased by fusing it to another protein. Even larger increases in activity were achieved by doubling the number of ice-binding sites by dimerization. Here, we have combined the two strategies by linking multiple outward-facing AFPs to a dendrimer to significantly increase both the size of the molecule and the number of ice-binding sites. Using a heterobifunctional cross-linker, we attached between 6 and 11 type III AFPs to a second-generation polyamidoamine (G2-PAMAM) dendrimer with 16 reactive termini. This heterogeneous sample of dendrimer-linked type III constructs showed a greater than 4-fold increase in freezing point depression over that of monomeric type III AFP. This multimerized AFP was particularly effective at ice recrystallization inhibition activity, likely because it can simultaneously bind multiple ice surfaces. Additionally, attachment to the dendrimer has afforded the AFP superior recovery from heat denaturation. Linking AFPs together via polymers can generate novel reagents for controlling ice growth and recrystallization. PMID:26267368

  7. Dendrimer-Linked Antifreeze Proteins Have Superior Activity and Thermal Recovery.

    PubMed

    Stevens, Corey A; Drori, Ran; Zalis, Shiran; Braslavsky, Ido; Davies, Peter L

    2015-09-16

    By binding to ice, antifreeze proteins (AFPs) depress the freezing point of a solution and inhibit ice recrystallization if freezing does occur. Previous work showed that the activity of an AFP was incrementally increased by fusing it to another protein. Even larger increases in activity were achieved by doubling the number of ice-binding sites by dimerization. Here, we have combined the two strategies by linking multiple outward-facing AFPs to a dendrimer to significantly increase both the size of the molecule and the number of ice-binding sites. Using a heterobifunctional cross-linker, we attached between 6 and 11 type III AFPs to a second-generation polyamidoamine (G2-PAMAM) dendrimer with 16 reactive termini. This heterogeneous sample of dendrimer-linked type III constructs showed a greater than 4-fold increase in freezing point depression over that of monomeric type III AFP. This multimerized AFP was particularly effective at ice recrystallization inhibition activity, likely because it can simultaneously bind multiple ice surfaces. Additionally, attachment to the dendrimer has afforded the AFP superior recovery from heat denaturation. Linking AFPs together via polymers can generate novel reagents for controlling ice growth and recrystallization.

  8. Geospatial Information Integration for Science Activity Planning at the Mars Desert Research Station

    NASA Astrophysics Data System (ADS)

    Berrios, Daniel C.; Sierhuis, Maarten; Keller, Richard M.

    NASA's Mobile Agents project leads coordinated planetary exploration simulations at the Mars Desert Research Station. Through ScienceOrganizer, a Web-based tool for organizing and providing contextual information for scientific data sets, remote teams of scientists access and annotate data sets, images, documents and other forms of scientific information, applying predefined semantic links and metadata using a Web browser. We designed and developed an experimental geographic information server that integrates remotely sensed images of scientific activity areas with information regarding activity plans, actors and data that had been characterized semantically using ScienceOrganizer. The server automatically obtains remotely sensed photographs of geographic survey sites at various resolutions and combines these images with scientific survey data to generate “context maps” illustrating the paths of survey actors and the sequence and types of data collected during simulated surface “extra-vehicular activities.” The remotely located scientific team found the context maps were extremely valuable for achieving and conveying activity plan consensus.

  9. Prioritizing Active Learning: An Exploration of Gateway Courses in Political Science

    ERIC Educational Resources Information Center

    Archer, Candace C.; Miller, Melissa K.

    2011-01-01

    Prior research in political science and other disciplines demonstrates the pedagogical and practical benefits of active learning. Less is known, however, about the extent to which active learning is used in political science classrooms. This study assesses the prioritization of active learning in "gateway" political science courses, paying…

  10. Does the Neighborhood Context Alter the Link between Youth's After-School Time Activities and Developmental Outcomes? A Multilevel Analysis

    ERIC Educational Resources Information Center

    Fauth, Rebecca C.; Roth, Jodie L.; Brooks-Gunn, Jeanne

    2007-01-01

    This article examines links between different measures of after-school time activity participation (5 specific activities and breadth) on youth's developmental outcomes (anxiety/depression, delinquency, and substance use) over 6 years and whether these links are moderated by neighborhood-level variables. The sample (N = 1,315) of 9- and…

  11. Teaching About the Links Between Soils and Climate: An International Year of Soil Outreach by the Soil Science Society of America

    NASA Astrophysics Data System (ADS)

    Brevik, Eric C.

    2015-04-01

    Soil scientists are well aware of the intimate links that exist between soils and climate, but the same is not always true of the broader population. In an attempt to help address this, the Soil Science Society of America (SSSA) has designated the theme "Soils and Climate" for the month of November, 2015 as part of the SSSA International Year of Soil (IYS) celebration. The topic has been further subdivided into three subthemes: 1) carbon sequestration and greenhouse gases, 2) Soils and past environments, and 3) Desertification and drought. Each subtheme outreach has two parts 1) lesson plans that K-12 educators can use in their classrooms, and 2) materials that a trained soil scientist can present to the general public. Activities developed for the theme include classroom activities to accompany an online game that students can play to see how farm management choices influence greenhouse gas emissions, questions to go with a vermicomposting activity, and discussion session questions to go with a movie on the USA Dust Bowl. All materials are available online free of charge. The Soils and Climate materials can be found at https://www.soils.org/iys/12-month-resources/november; all of the SSSA IYS materials can be found at https://www.soils.org/iys.

  12. Deductive reasoning, brain maturation, and science concept acquisition: Are they linked?

    NASA Astrophysics Data System (ADS)

    Lawson, Anton E.

    of Levine and Prueitt (1989) is presented. The advance in reasoning that presumably results from effective operation of the frontal lobes is seen as a fundamental advance in intellectual development because it enables children to employ an inductive-deductive reasoning pattern to change their minds when confronted with contradictory evidence regarding features of perceptible objects, a skill necessary for descriptive concept acquisition. It is suggested that a further qualitative advance in intellectual development occurs when an analogous pattern of abductive-deductive reasoning is applied to hypothetical objects and/or processes to allow for alternative hypothesis testing and theoretical concept acquisition. Apparently this is the reasoning pattern needed to derive an effective problem-solving strategy to solve the concept acquisition tasks of Lawson et al. (1991) when direct instruction is not provided. Implications for the science classroom are suggested.

  13. Learning about Earth Science: Tables and Tabulations. Superific Science Book X. A Good Apple Science Activity Book for Grades 5-8+.

    ERIC Educational Resources Information Center

    Conway, Lorraine

    In an effort to provide science teachers with the tables and scales most often used in teaching earth science, this document was designed to coordinate each table with meaningful activities, projects and experiments. The major areas covered by the booklet are: (1) electromagnetic waves (with activities about light waves and sound waves); (2) the…

  14. Links between osteoarthritis and diabetes: implications for management from a physical activity perspective.

    PubMed

    Piva, Sara R; Susko, Allyn M; Khoja, Samannaaz S; Josbeno, Deborah A; Fitzgerald, G Kelley; Toledo, Frederico G S

    2015-02-01

    Osteoarthritis (OA) and type 2 diabetes mellitus (T2DM) often coexist in older adults. Those with T2DM are more susceptible to developing arthritis, which has been traditionally attributed to common risk factors, namely, age and obesity. Alterations in lipid metabolism and hyperglycemia might directly impact cartilage health and subchondral bone, contributing to the development/progression of OA. Adequate management of older persons with both conditions benefits from a comprehensive understanding of the associated risk factors. We discuss common risk factors and emerging links between OA and T2DM, emphasizing the importance of physical activity and the implications of safe and effective physical activity. PMID:25453302

  15. The Effects of Aesthetic Science Activities on Improving At-Risk Families Children's Anxiety About Learning Science and Positive Thinking

    NASA Astrophysics Data System (ADS)

    Hong, Zuway-R.; Lin, Huann-shyang; Chen, Hsiang-Ting; Wang, Hsin-Hui; Lin, Chia-Jung

    2014-01-01

    The purpose of this study was to explore the effects of aesthetic science activities on improving elementary school at-risk families' children's positive thinking, attitudes toward science, and decreasing their anxiety about learning science. Thirty-six 4th-grade children from at-risk families volunteered to participate in a 12-week intervention and formed the experimental group; another 97 typical 4th graders were randomly selected to participant in the assessment and were used as the comparison group. The treatment for experimental group children emphasized scaffolding aesthetic science activities and inquiry strategies. The Elementary School Student Questionnaire was administered to assess all children's positive thinking, attitudes toward science, and anxiety about learning science. In addition, nine target children from the experimental group with the lowest scores on either positive thinking, or attitudes toward science, or with the highest scores on anxiety about learning science in the pre-test were recruited to be interviewed at the end of the intervention and observed weekly. Confirmatory factor analyses, analyses of covariance, and content theme analysis assessed the similarities and differences between groups. It was found that the at-risk families' children were motivated by the treatment and made significant progress on positive thinking and attitudes toward science, and also decreased their anxiety about learning science. The findings from interviews and classroom observations also revealed that the intervention made differences in children's affective perceptions of learning science. Implication and research recommendation are discussed.

  16. Elementary teachers committed to actively teaching science and engineering

    NASA Astrophysics Data System (ADS)

    Opperman, Julianne Radkowski

    Committed elementary teachers of science and engineering, members of a professional learning community called Collaborative Conversations in STEM, were studied to elicit their perceptions of experiences that influenced their commitment to, and their pedagogical content knowledge of, STEM teaching and learning. The hermeneutic phenomenological interviews enabled the teachers to express their beliefs in their own words. Data analysis employed a theoretical framework that investigated teacher epistemology and knowledge in light of their experiences. Findings revealed a web of lifelong experiences unique to each individual, and evidential of the committed elementary scientist-teachers' present day values, teaching epistemology, lifelong learning, and emotional and intellectual engagement. Scientist-teachers are individuals whose teaching and learning characteristics reflect those of scientists and engineers. Evidence indicated that no single transformative learning experience resulted in those elementary teachers' commitment to STEM teaching and learning, but recent professional development activities were influential. Formal K-16 STEM learning was not uniformly or positively influential to the teachers' commitment to, or knowledge of, STEM. Findings suggest that ongoing professional development for STEM teaching and learning can influence elementary teachers to become committed to actively teaching STEM. The Collaborative Conversations in STEM provided intellectual and emotional engagement that empowered the teachers to provide STEM teaching and learning for their students and their colleagues overcoming impediments encountered in a literacy-focused curriculum. Elementary teachers actively committed to teaching science and engineering can undergo further transformation and emerge as leaders.

  17. Activities of the National Institute of Radiological Sciences

    NASA Astrophysics Data System (ADS)

    1994-01-01

    This annual report presents activities at the National Institute of Radiological Sciences (NIRS) in Japan during the period April 1992-March 1993. The activities are divided into research, technical aids, training, medical services, management, library or editing, and international cooperation. Research activities are arranged with twelve sections. The first section on special researches deals with continuing research projects entitled: (1) 'Biological Risk Evaluation in Public Exposure'; (2) 'Exposure Assessment in the Environment and the Public Through Food Chain'; (3) 'Medical Use of Accelerated Heavy Ions'; and (4) 'Preliminary Study for the Demonstration of Dose-Response Relationships in Low-Dose Range'. All projects except for project (4) will be finished up to March 1993. The section of assigned researches covers four titles. The section of ordinary researches covers physics (four titles), pharmacochemistry (four), biology (three), genetics (four), physiopathology (four), cytological radiation injuries (three), internal exposure (four), environmental science (four), clinical research (four), clinical research for radiation injuries (three), medical use of heavy particles (three), environmental radiation ecology (three), and aquatic radiation ecology (two). The section on technical aids gives an overview of technical services, radiation safety, animal and plant management, and cyclotron management. Appendices give the information on personnel in NIRS.

  18. Computer Science Research Institute 2005 annual report of activities.

    SciTech Connect

    Watts, Bernadette M.; Collis, Samuel Scott; Ceballos, Deanna Rose; Womble, David Eugene

    2008-04-01

    This report summarizes the activities of the Computer Science Research Institute (CSRI) at Sandia National Laboratories during the period January 1, 2005 to December 31, 2005. During this period, the CSRI hosted 182 visitors representing 83 universities, companies and laboratories. Of these, 60 were summer students or faculty. The CSRI partially sponsored 2 workshops and also organized and was the primary host for 3 workshops. These 3 CSRI sponsored workshops had 105 participants, 78 from universities, companies and laboratories, and 27 from Sandia. Finally, the CSRI sponsored 12 long-term collaborative research projects and 3 Sabbaticals.

  19. Computer Science Research Institute 2003 annual report of activities.

    SciTech Connect

    DeLap, Barbara J.; Womble, David Eugene; Ceballos, Deanna Rose

    2006-03-01

    This report summarizes the activities of the Computer Science Research Institute (CSRI) at Sandia National Laboratories during the period January 1, 2003 to December 31, 2003. During this period the CSRI hosted 164 visitors representing 78 universities, companies and laboratories. Of these 78 were summer students or faculty members. The CSRI partially sponsored 5 workshops and also organized and was the primary host for 3 workshops. These 3 CSRI sponsored workshops had 178 participants--137 from universities, companies and laboratories, and 41 from Sandia. Finally, the CSRI sponsored 18 long-term collaborative research projects and 5 Sabbaticals.

  20. Computer Science Research Institute 2004 annual report of activities.

    SciTech Connect

    DeLap, Barbara J.; Womble, David Eugene; Ceballos, Deanna Rose

    2006-03-01

    This report summarizes the activities of the Computer Science Research Institute (CSRI) at Sandia National Laboratories during the period January 1, 2004 to December 31, 2004. During this period the CSRI hosted 166 visitors representing 81 universities, companies and laboratories. Of these 65 were summer students or faculty. The CSRI partially sponsored 2 workshops and also organized and was the primary host for 4 workshops. These 4 CSRI sponsored workshops had 140 participants--74 from universities, companies and laboratories, and 66 from Sandia. Finally, the CSRI sponsored 14 long-term collaborative research projects and 5 Sabbaticals.

  1. 77 FR 16846 - National Science Advisory Board for Biosecurity Meeting; Office of Biotechnology Activities...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-22

    ...; Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of Closed...: Ronna Hill, NSABB Program Assistant, NIH Office of Biotechnology Activities, 6705 Rockledge Drive,...

  2. Rights of animals, perceptions of science, and political activism: profile of American animal rights activities.

    PubMed

    Jamison, W V; Lunch, W M

    1992-01-01

    This article reports original research examining characteristics of the active followers of the American animal rights movement. Typical respondents were Caucasian, highly educated urban professional women approximately thirty years old with a median income of $33,000 (1989). Most activists think of themselves as Democrats or as Independents, and have moderate to liberal political views. They were often suspicious of science and made no distinction between basic and applied science, or public versus private animal-based research. The research suggests that animal rights activism is part of a symbolic manifestation of egalitarian social and political views concerning scientific and technological change.

  3. New evidence for a link between lightning activity and tropical upper cloud coverage

    NASA Astrophysics Data System (ADS)

    Sato, Mitsuteru; Fukunishi, Hiroshi

    2005-06-01

    We report new evidence for a link between lightning activity and tropical upper cloud coverage. Using 1-100 Hz ELF magnetic field waveform data obtained at Syowa station, we analyzed Schumann resonance (SR) spectral intensity variation to investigate characteristics of lightning activity changes. Further, we performed the cross-spectral analysis between the spectral intensity variation and the tropical upper cloud coverage at high altitude derived from infrared cloud images. It is found that the tropical upper cloud coverage and the lightning activity change with the same periodicity and a clear anti-phase relation. These results imply that the lightning activity is closely related to the meteorological dynamics in the troposphere. This fact demonstrates that tropical upper cloud coverage may be continuously monitored by SRs measured at a single site on the Earth's surface.

  4. Linking `The Book of Nature' and `The Book of Science': Using Circular Motion as an Exemplar beyond the Textbook

    NASA Astrophysics Data System (ADS)

    Stinner, Arthur

    Bacon exhorted the natural philosophers of his day to read and interpret the book of nature by clever and cunning experimentation. The increasing scientific activity after Bacon and Galileo, however, quickly produced a second book. This was a book of interpretations of nature, namely the the book of science. Newton went beyond Bacon and Galileo and developed an ongoing dialogue between these two books, a repeated give and take between mathematical construct and physical reality. Unfortunately, the physics textbook, the book of science the students read, does not acquaint them with this style of reasoning. As an example of high-grade scientific thinking this paper discusses Newton's long struggle with the concepts of inertia and especially of centrifugal force. In his quest to understand the dynamics of circular motion Newton clearly progressed through four levels of conceptualizations, leading to progressively less severe discrepancies, in his ascent to a full understanding of centripetal acceleration. While it is not possible or desirable to expect teachers or students to recapitulate high-grade scientific thinking, partial retelling of the intellectual struggle that was involved in establishing important scientific concepts must be seen as important. This kind of pedagogy, however, requires that physics teachers have a good understanding of the history of scientific ideas as well as the findings of cognitive science.

  5. An Analysis of Teacher Discourse that Introduces Real Science Activities to High School Students

    ERIC Educational Resources Information Center

    Hsu, Pei-Ling; Roth, Wolff-Michael

    2009-01-01

    Most academic science educators encourage teachers to provide their students with access to more authentic science activities. What can and do teachers say to increase students' interests in participating in opportunities to do real science? What are the discursive "resources" they draw on to introduce authentic science to students? The purpose of…

  6. Analyzing Science Activities in Force and Motion Concepts: A Design of an Immersion Unit

    ERIC Educational Resources Information Center

    Ayar, Mehmet C.; Aydeniz, Mehmet; Yalvac, Bugrahan

    2015-01-01

    In this paper, we analyze the science activities offered at 7th grade in the Turkish science and technology curriculum along with addressing the curriculum's original intent. We refer to several science education researchers' ideas, including Chinn & Malhotra's (Science Education, 86:175--218, 2002) theoretical framework and…

  7. Assessing the Impact Participation in Science Journalism Activities Has on Scientific Literacy among High School Students

    ERIC Educational Resources Information Center

    Farrar, Cathy

    2012-01-01

    As part of the National Science Foundation Science Literacy through Science Journalism (SciJourn) research and development initiative (http://www.scijourn.org; Polman, Saul, Newman, and Farrar, 2008) a quasi-experimental design was used to investigate what impact incorporating science journalism activities had on students' scientific literacy.…

  8. Intramolecular cross-linking of domains at the active site links A1 and B subfragments of the Ca2+-ATPase of sarcoplasmic reticulum.

    PubMed

    Ross, D C; McIntosh, D B

    1987-02-15

    Glutaraldehyde treatment of sarcoplasmic reticulum vesicles results in formation of cross-linked Ca2+-ATPase oligomers. Under limiting reaction conditions, where minimal interpolypeptide cross-linking occurs, hydrodynamic properties of the monomer are altered, such that, on sodium dodecyl sulfate-polyacrylamide electrophoresis, the enzyme migrates with an apparent molecular weight of 125,000 (E(125], as compared to the native enzyme (E(110]. The E(125) species was also formed following reaction with other cross-linking bis-aldehydes, with formaldehyde and with a bissuccinimidyl ester. Derivitization resulted in inactivation of ATPase activity and of phosphoprotein formation from Pi. E(125) formation was inhibited by ATP, ADP, AMPPCP, and orthovanadate, and by specific modification of active site Lys-514 with fluorescein-5'-isothiocyanate. Tryptic cleavage patterns of the glutaraldehyde-modified enzyme were consistent with covalent linkage of A1 and B fragments that have been postulated to comprise the phosphorylation and nucleotide-binding domains (MacLennan, D. H., Brandt, C. J., Korczak, B., and Green, N. M. (1985) Nature 316, 696-700). The denaturing detergent, sodium dodecyl sulfate, prevented cross-link formation. Interdomain cross-linking was inhibited by prior modification with either 2,4,6-trinitrobenzene sulfonate, phenylglyoxal, or pyridoxal-5'-phosphate but was unaffected by thiol group modification with iodoacetate or N-ethylmaleimide, suggesting involvement of lysine residues. These findings indicate that intramolecular cross-linking at the active site of the Ca2+-ATPase involves phosphorylation- and ATP-binding domains that are widely separated in the linear sequence. PMID:2950084

  9. "Our Zoo to You": The Link between Zoo Animals in the Classroom and Science and Literacy Concepts in First-Grade Journal Writing

    ERIC Educational Resources Information Center

    Wilson, Kathleen; Trainin, Guy; Laughridge, Virginia; Brooks, David; Wickless, Mimi

    2011-01-01

    This study examined first-grade students' journal writing to determine how placing live zoo animals in classrooms for science education links to students' emergent and early writing. Students were asked to write journal entries during the daily language arts period. Although no direct instruction in informational text writing was offered, teachers…

  10. Linking the Components of a University Program to the Qualification Profile of Graduates: The Case of a Sustainability-Oriented Environmental Science Curriculum

    ERIC Educational Resources Information Center

    Hansmann, Ralf

    2009-01-01

    A university Environmental Sciences curriculum is described against the background of requirements for environmental problem solving for sustainability and then analyzed using data from regular surveys of graduates (N = 373). Three types of multiple regression models examine links between qualifications and curriculum components in order to derive…

  11. The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation

    PubMed Central

    Baker, Sandra M.; Loren, Cassandra P.; Haley, Kristina M.; Itakura, Asako; Pang, Jiaqing; Greenberg, Daniel L.; David, Larry L.; Manser, Ed; Chernoff, Jonathan; McCarty, Owen J. T.

    2013-01-01

    Regulation of the platelet actin cytoskeleton by the Rho family of small GTPases is essential for the proper maintenance of hemostasis. However, little is known about how intracellular platelet activation from Rho GTPase family members, including Rac, Cdc42, and Rho, translate into changes in platelet actin structures. To better understand how Rho family GTPases coordinate platelet activation, we identified platelet proteins associated with Rac1, a Rho GTPase family member, and actin regulatory protein essential for platelet hemostatic function. Mass spectrometry analysis revealed that upon platelet activation with thrombin, Rac1 associates with a set of effectors of the p21-activated kinases (PAKs), including GIT1, βPIX, and guanine nucleotide exchange factor GEFH1. Platelet activation by thrombin triggered the PAK-dependent phosphorylation of GIT1, GEFH1, and other PAK effectors, including LIMK1 and Merlin. PAK was also required for the thrombin-mediated activation of the MEK/ERK pathway, Akt, calcium signaling, and phosphatidylserine (PS) exposure. Inhibition of PAK signaling prevented thrombin-induced platelet aggregation and blocked platelet focal adhesion and lamellipodia formation in response to thrombin. Together, these results demonstrate that the PAK signaling system is a key orchestrator of platelet actin dynamics, linking Rho GTPase activation downstream of thrombin stimulation to PAK effector function, MAP kinase activation, calcium signaling, and PS exposure in platelets. PMID:23784547

  12. Activation of lactoperoxidase by heme-linked protonation and heme-independent iodide binding.

    PubMed

    Toyama, Akira; Tominaga, Aya; Inoue, Tatsuo; Takeuchi, Hideo

    2010-01-01

    Lactoperoxidase (LPO), a mammalian secretory heme peroxidase, catalyzes the oxidation of thiocyanate by hydrogen peroxide to produce hypothiocyanate, an antibacterial agent. Although LPO is known to be activated at acidic pH and in the presence of iodide, the structural basis of the activation is not well understood. We have examined the effects of pH and iodide concentration on the catalytic activity and the structure of LPO. Electrochemical and colorimetric assays have shown that the catalytic activity is maximized at pH 4.5. The heme Soret absorption band exhibits a small red-shift at pH 5.0 upon acidification, which is ascribable to a structural transition from a neutral to an acidic form. Resonance Raman spectra suggest that the heme porphyrin core is slightly contracted and the Fe-His bond is strengthened in the acidic form compared to the neutral form. The structural change of LPO upon activation at acidic pH is similar to that observed for myeloperoxidase, another mammalian heme peroxidase, upon activation at neutral pH. Binding of iodide enhances the catalytic activity of LPO without affecting either the optimum pH of activity or the heme structure, implying that the iodide binding occurs at a protein site away from the heme-linked protonation site.

  13. Metal active site elasticity linked to activation of homocysteine in methionine synthases

    SciTech Connect

    Koutmos, Markos; Pejchal, Robert; Bomer, Theresa M.; Matthews, Rowena G.; Smith, Janet L.; Ludwig, Martha L.

    2008-04-02

    Enzymes possessing catalytic zinc centers perform a variety of fundamental processes in nature, including methyl transfer to thiols. Cobalamin-independent (MetE) and cobalamin-dependent (MetH) methionine synthases are two such enzyme families. Although they perform the same net reaction, transfer of a methyl group from methyltetrahydrofolate to homocysteine (Hcy) to form methionine, they display markedly different catalytic strategies, modular organization, and active site zinc centers. Here we report crystal structures of zinc-replete MetE and MetH, both in the presence and absence of Hcy. Structural investigation of the catalytic zinc sites of these two methyltransferases reveals an unexpected inversion of zinc geometry upon binding of Hcy and displacement of an endogenous ligand in both enzymes. In both cases a significant movement of the zinc relative to the protein scaffold accompanies inversion. These structures provide new information on the activation of thiols by zinc-containing enzymes and have led us to propose a paradigm for the mechanism of action of the catalytic zinc sites in these and related methyltransferases. Specifically, zinc is mobile in the active sites of MetE and MetH, and its dynamic nature helps facilitate the active site conformational changes necessary for thiol activation and methyl transfer.

  14. NASA's Future Active Remote Sensing Missing for Earth Science

    NASA Technical Reports Server (NTRS)

    Hartley, Jonathan B.

    2000-01-01

    Since the beginning of space remote sensing of the earth, there has been a natural progression widening the range of electromagnetic radiation used to sense the earth, and slowly, steadily increasing the spatial, spectral, and radiometric resolution of the measurements. There has also been a somewhat slower trend toward active measurements across the electromagnetic spectrum, motivated in part by increased resolution, but also by the ability to make new measurements. Active microwave instruments have been used to measure ocean topography, to study the land surface. and to study rainfall from space. Future NASA active microwave missions may add detail to the topographical studies, sense soil moisture, and better characterize the cryosphere. Only recently have active optical instruments been flown in space by NASA; however, there are currently several missions in development which will sense the earth with lasers and many more conceptual active optical missions which address the priorities of NASA's earth science program. Missions are under development to investigate the structure of the terrestrial vegetation canopy, to characterize the earth's ice caps, and to study clouds and aerosols. Future NASA missions may measure tropospheric vector winds and make vastly improved measurements of the chemical components of the earth's atmosphere.

  15. BioHackathon series in 2011 and 2012: penetration of ontology and linked data in life science domains

    PubMed Central

    2014-01-01

    The application of semantic technologies to the integration of biological data and the interoperability of bioinformatics analysis and visualization tools has been the common theme of a series of annual BioHackathons hosted in Japan for the past five years. Here we provide a review of the activities and outcomes from the BioHackathons held in 2011 in Kyoto and 2012 in Toyama. In order to efficiently implement semantic technologies in the life sciences, participants formed various sub-groups and worked on the following topics: Resource Description Framework (RDF) models for specific domains, text mining of the literature, ontology development, essential metadata for biological databases, platforms to enable efficient Semantic Web technology development and interoperability, and the development of applications for Semantic Web data. In this review, we briefly introduce the themes covered by these sub-groups. The observations made, conclusions drawn, and software development projects that emerged from these activities are discussed. PMID:24495517

  16. BioHackathon series in 2011 and 2012: penetration of ontology and linked data in life science domains.

    PubMed

    Katayama, Toshiaki; Wilkinson, Mark D; Aoki-Kinoshita, Kiyoko F; Kawashima, Shuichi; Yamamoto, Yasunori; Yamaguchi, Atsuko; Okamoto, Shinobu; Kawano, Shin; Kim, Jin-Dong; Wang, Yue; Wu, Hongyan; Kano, Yoshinobu; Ono, Hiromasa; Bono, Hidemasa; Kocbek, Simon; Aerts, Jan; Akune, Yukie; Antezana, Erick; Arakawa, Kazuharu; Aranda, Bruno; Baran, Joachim; Bolleman, Jerven; Bonnal, Raoul Jp; Buttigieg, Pier Luigi; Campbell, Matthew P; Chen, Yi-An; Chiba, Hirokazu; Cock, Peter Ja; Cohen, K Bretonnel; Constantin, Alexandru; Duck, Geraint; Dumontier, Michel; Fujisawa, Takatomo; Fujiwara, Toyofumi; Goto, Naohisa; Hoehndorf, Robert; Igarashi, Yoshinobu; Itaya, Hidetoshi; Ito, Maori; Iwasaki, Wataru; Kalaš, Matúš; Katoda, Takeo; Kim, Taehong; Kokubu, Anna; Komiyama, Yusuke; Kotera, Masaaki; Laibe, Camille; Lapp, Hilmar; Lütteke, Thomas; Marshall, M Scott; Mori, Takaaki; Mori, Hiroshi; Morita, Mizuki; Murakami, Katsuhiko; Nakao, Mitsuteru; Narimatsu, Hisashi; Nishide, Hiroyo; Nishimura, Yosuke; Nystrom-Persson, Johan; Ogishima, Soichi; Okamura, Yasunobu; Okuda, Shujiro; Oshita, Kazuki; Packer, Nicki H; Prins, Pjotr; Ranzinger, Rene; Rocca-Serra, Philippe; Sansone, Susanna; Sawaki, Hiromichi; Shin, Sung-Ho; Splendiani, Andrea; Strozzi, Francesco; Tadaka, Shu; Toukach, Philip; Uchiyama, Ikuo; Umezaki, Masahito; Vos, Rutger; Whetzel, Patricia L; Yamada, Issaku; Yamasaki, Chisato; Yamashita, Riu; York, William S; Zmasek, Christian M; Kawamoto, Shoko; Takagi, Toshihisa

    2014-01-01

    The application of semantic technologies to the integration of biological data and the interoperability of bioinformatics analysis and visualization tools has been the common theme of a series of annual BioHackathons hosted in Japan for the past five years. Here we provide a review of the activities and outcomes from the BioHackathons held in 2011 in Kyoto and 2012 in Toyama. In order to efficiently implement semantic technologies in the life sciences, participants formed various sub-groups and worked on the following topics: Resource Description Framework (RDF) models for specific domains, text mining of the literature, ontology development, essential metadata for biological databases, platforms to enable efficient Semantic Web technology development and interoperability, and the development of applications for Semantic Web data. In this review, we briefly introduce the themes covered by these sub-groups. The observations made, conclusions drawn, and software development projects that emerged from these activities are discussed.

  17. Recent Electric Propulsion Development Activities for NASA Science Missions

    NASA Technical Reports Server (NTRS)

    Pencil, Eric J.

    2009-01-01

    (The primary source of electric propulsion development throughout NASA is managed by the In-Space Propulsion Technology Project at the NASA Glenn Research Center for the Science Mission Directorate. The objective of the Electric Propulsion project area is to develop near-term electric propulsion technology to enhance or enable science missions while minimizing risk and cost to the end user. Major hardware tasks include developing NASA s Evolutionary Xenon Thruster (NEXT), developing a long-life High Voltage Hall Accelerator (HIVHAC), developing an advanced feed system, and developing cross-platform components. The objective of the NEXT task is to advance next generation ion propulsion technology readiness. The baseline NEXT system consists of a high-performance, 7-kW ion thruster; a high-efficiency, 7-kW power processor unit (PPU); a highly flexible advanced xenon propellant management system (PMS); a lightweight engine gimbal; and key elements of a digital control interface unit (DCIU) including software algorithms. This design approach was selected to provide future NASA science missions with the greatest value in mission performance benefit at a low total development cost. The objective of the HIVHAC task is to advance the Hall thruster technology readiness for science mission applications. The task seeks to increase specific impulse, throttle-ability and lifetime to make Hall propulsion systems applicable to deep space science missions. The primary application focus for the resulting Hall propulsion system would be cost-capped missions, such as competitively selected, Discovery-class missions. The objective of the advanced xenon feed system task is to demonstrate novel manufacturing techniques that will significantly reduce mass, volume, and footprint size of xenon feed systems over conventional feed systems. This task has focused on the development of a flow control module, which consists of a three-channel flow system based on a piezo-electrically actuated

  18. Square Wheels and Other Easy-To-Build Hands-On Science Activities. An Exploratorium Science Snackbook.

    ERIC Educational Resources Information Center

    Rathjen, Don; Doherty, Paul

    This book, part of The Exploratorium science "snackbook" series, explains science with a hands-on approach. Activities include: (1) "3-D Shadow"; (2) "Bits and Bytes"; (3) "Circuit Workbench"; (4) "Diamagnetic Repulsion"; (5) "Film Can Racer"; (6) "Fractal Patterns"; (7) "Hoop Nightmares"; (8) "Hydraulic Arm"; (9) "Hyperbolic Slot"; (10) "Light…

  19. Science Action Labs Part 3: Puzzlers. An Innovative Collection of Hands-On Science Activities and Labs.

    ERIC Educational Resources Information Center

    Shevick, Ed

    This book contains hands-on science laboratory activities for grades 4 through 9 that use discrepant events to challenge students. All of the "puzzlers" are based upon science principles and include directions for building gadgets that explain the "puzzlers." Topics covered include: volume conservation, magnetic phenomena, optical illusions,…

  20. Linking morphology with activity through the lifetime of pretreated PtNi nanostructured thin film catalysts

    DOE PAGES

    Cullen, David A.; Lopez-Haro, Miguel; Bayle-Guillemaud, Pascale; Debe, Mark; Steinbach, Andrew J.; Guetaz, L.

    2015-04-10

    In this study, the nanoscale morphology of highly active Pt3Ni7 nanostructured thin film fuel cell catalysts is linked with catalyst surface area and activity following catalyst pretreatments, conditioning and potential cycling. The significant role of fuel cell conditioning on the structure and composition of these extended surface catalysts is demonstrated by high resolution imaging, elemental mapping and tomography. The dissolution of Ni during fuel cell conditioning leads to highly complex, porous structures which were visualized in 3D by electron tomography. Quantification of the rendered surfaces following catalyst pretreatment, conditioning, and cycling shows the important role pore structure plays in surfacemore » area, activity, and durability.« less

  1. Linking morphology with activity through the lifetime of pretreated PtNi nanostructured thin film catalysts

    SciTech Connect

    Cullen, David A.; Lopez-Haro, Miguel; Bayle-Guillemaud, Pascale; Debe, Mark; Steinbach, Andrew J.; Guetaz, L.

    2015-04-10

    In this study, the nanoscale morphology of highly active Pt3Ni7 nanostructured thin film fuel cell catalysts is linked with catalyst surface area and activity following catalyst pretreatments, conditioning and potential cycling. The significant role of fuel cell conditioning on the structure and composition of these extended surface catalysts is demonstrated by high resolution imaging, elemental mapping and tomography. The dissolution of Ni during fuel cell conditioning leads to highly complex, porous structures which were visualized in 3D by electron tomography. Quantification of the rendered surfaces following catalyst pretreatment, conditioning, and cycling shows the important role pore structure plays in surface area, activity, and durability.

  2. Examination of Pre-Service Science Teachers' Activities Using Problem Based Learning Method

    ERIC Educational Resources Information Center

    Ekici, Didem Inel

    2016-01-01

    In this study, both the activities prepared by pre-service science teachers regarding the Problem Based Learning method and the pre-service science teachers' views regarding the method were examined before and after applying their activities in a real class environment. 69 pre-service science teachers studying in the 4th grade of the science…

  3. Active Galaxies Educational Unit: An Educator's Guide with Activities in Science and Mathematics.

    ERIC Educational Resources Information Center

    National Aeronautics and Space Administration, Washington, DC.

    As a part of its educational effort, the National Aeronautics and Space Administration (NASA) Education and Public Outreach group at Sonoma State University (SSU) has put together a series of activities based on the science of one of NASA's exciting space missions, the Gamma-ray Large Area Space Telescope (GLAST). GLAST is a NASA satellite planned…

  4. Innovative Project Activities in Science [From the NSTA Study of Innovative Project Activities

    ERIC Educational Resources Information Center

    Science Teacher, 1975

    1975-01-01

    Describes four projects chosen as innovative project activities in science which exhibited identification of unique or novel problems and creative approaches to their solutions. Projects included a study of fish in Lake Erie, a goat raising project, an analysis of terrestrial plant ecology and soil composition, and a study of marine and wetlands…

  5. Enhancing science education through extracurricular activities: A retrospective study of "Suzy Science and the Whiz Kids(c)"

    NASA Astrophysics Data System (ADS)

    Kralina, Linda M.

    Extracurricular activities (ECA) are informal settings offering free-choice experiences that are generally voluntary, open-ended, non-sequential, self-directed, hands-on, and evaluation-free. This mixed methods study investigates participation in a high school science ECA by collecting the memories of former student members for their perceptions of engagement as well as social positioning. First, this study examines the levels in which the science club engaged these members, particularly females, in science and teaching. Second, the study also ascertains how participation in the club allowed members to explore new identities and fostered the development of new skills, actions and behaviors, expanding possible future trajectories of identification, specifically in science- and education-related career fields. Based on a review of the related literature regarding engagement and identity formation and the reconstructed reality from the memories of these students and sponsor, a theoretical framework has been constructed, based on seven essential elements of informal learning for an engaging as well as a socially constructive high school science ECA. The most significant findings are (1) the high correlation between engagement, specifically, cognitive engagement with social positioning, (2) the important role of emotional engagement in science ECA, (3) the major perception roadblocks to science learning that can be overcome, particularly for females in physical science, and (4) the importance of the teacher-student interactions in science ECA. Articulating a theoretical framework to legitimate the power of informal learning structures may help other educators to understand the potential benefits of science ECA and thus, increase opportunities for such experiential activities in order to enhance engagement and expand positioning of their students in science. More engaging, socially constructive science ECA have the potential to enhance science education.

  6. The Carbohydrate-linked Phosphorylcholine of the Parasitic Nematode Product ES-62 Modulates Complement Activation*

    PubMed Central

    Ahmed, Umul Kulthum; Maller, N. Claire; Iqbal, Asif J.; Al-Riyami, Lamyaa; Harnett, William; Raynes, John G.

    2016-01-01

    Parasitic nematodes manufacture various carbohydrate-linked phosphorylcholine (PCh)-containing molecules, including ES-62, a protein with an N-linked glycan terminally substituted with PCh. The PCh component is biologically important because it is required for immunomodulatory effects. We showed that most ES-62 was bound to a single protein, C-reactive protein (CRP), in normal human serum, displaying a calcium-dependent, high-avidity interaction and ability to form large complexes. Unexpectedly, CRP binding to ES-62 failed to efficiently activate complement as far as the C3 convertase stage in comparison with PCh-BSA and PCh-containing Streptococcus pneumoniae cell wall polysaccharide. C1q capture assays demonstrated an ES-62-CRP-C1q interaction in serum. The three ligands all activated C1 and generated C4b to similar extents. However, a C2a active site was not generated following ES-62 binding to CRP, demonstrating that C2 cleavage was far less efficient for ES-62-containing complexes. We proposed that failure of C2 cleavage was due to the flexible nature of carbohydrate-bound PCh and that reduced proximity of the C1 complex was the reason that C2 was poorly cleaved. This was confirmed using synthetic analogues that were similar to ES-62 only in respect of having a flexible PCh. Furthermore, ES-62 was shown to deplete early complement components, such as the rate-limiting C4, following CRP interaction and thereby inhibit classical pathway activation. Thus, flexible PCh-glycan represents a novel mechanism for subversion of complement activation. These data illustrate the importance of the rate-limiting C4/C2 stage of complement activation and reveal a new addition to the repertoire of ES-62 immunomodulatory mechanisms with possible therapeutic applications. PMID:27044740

  7. Caught in the act: covalent cross-linking captures activator-coactivator interactions in vivo.

    PubMed

    Krishnamurthy, Malathy; Dugan, Amanda; Nwokoye, Adaora; Fung, Yik-Hong; Lancia, Jody K; Majmudar, Chinmay Y; Mapp, Anna K

    2011-12-16

    Currently there are few methods suitable for the discovery and characterization of transient, moderate affinity protein-protein interactions in their native environment, despite their prominent role in a host of cellular functions including protein folding, signal transduction, and transcriptional activation. Here we demonstrate that a genetically encoded photoactivatable amino acid, p-benzoyl-l-phenylalanine, can be used to capture transient and/or low affinity binding partners in an in vivo setting. In this study, we focused on ensnaring the coactivator binding partners of the transcriptional activator VP16 in S. cerevisiae. The interactions between transcriptional activators and coactivators in eukaryotes are moderate in affinity and short-lived, and due in part to these characteristics, identification of the direct binding partners of activators in vivo has met with only limited success. We find through in vivo photo-cross-linking that VP16 contacts the Swi/Snf chromatin-remodeling complex through the ATPase Snf2(BRG1/BRM) and the subunit Snf5 with two distinct regions of the activation domain. An analogous experiment with Gal4 reveals that Snf2 is also a target of this activator. These results suggest that Snf2 may be a valuable target for small molecule probe discovery given the prominent role the Swi/Snf complex family plays in development and in disease. More significantly, the successful implementation of the in vivo cross-linking methodology in this setting demonstrates that it can be applied to the discovery and characterization of a broad range of transient and/or modest affinity protein-protein interactions. PMID:21977905

  8. Synthesis and antimicrobial activity of some novel cross-linked chitosan hydrogels.

    PubMed

    Mohamed, Nadia Ahmed; Fahmy, Mona Mohamed

    2012-01-01

    Four novel hydrogels based on chitosan were synthesized via a cross-linking reaction of chitosan with different concentrations of oxalyl bis 4-(2,5-dioxo-2H-pyrrol- 1(5H)-yl)benzamide. Their structures were confirmed by fourier transform infrared X-ray (FTIR), scanning electron microscopy (SEM) and X-ray diffraction. The antimicrobial activities of the hydrogels against two crop-threatening pathogenic fungi namely: Aspergillus fumigatus (A. fumigatus, RCMBA 06002), and Aspergillus niger (A. niger, RCMBA 06106), and five bacterial species namely: Bacillis subtilis (B. subtilis, RCMBA 6005), Staphylococcus aureus (S. aureus, RCMBA 2004), Streptococcus pneumoniae (S. pneumonia, RCMB 000101) as Gram positive bacteria, and Salmonella typhimurium (S. typhimurium, RCMB 000104), and Escherichia coli (E. coli, RCMBA 5003) as Gram negative bacteria have been investigated. The prepared hydrogels showed much higher antimicrobial activities than that of the parent chitosan. The hydrogels were more potent in case of Gram-positive bacteria than Gram-negative bacteria. Increasing the degree of cross-linking in the hydrogels resulted in a weaker antimicrobial activity. PMID:23109847

  9. Synthesis and Antimicrobial Activity of Some Novel Cross-Linked Chitosan Hydrogels

    PubMed Central

    Mohamed, Nadia Ahmed; Fahmy, Mona Mohamed

    2012-01-01

    Four novel hydrogels based on chitosan were synthesized via a cross-linking reaction of chitosan with different concentrations of oxalyl bis 4-(2,5-dioxo-2H-pyrrol- 1(5H)-yl)benzamide. Their structures were confirmed by fourier transform infrared X-ray (FTIR), scanning electron microscopy (SEM) and X-ray diffraction. The antimicrobial activities of the hydrogels against two crop-threatening pathogenic fungi namely: Aspergillus fumigatus (A. fumigatus, RCMBA 06002), and Aspergillus niger (A. niger, RCMBA 06106), and five bacterial species namely: Bacillis subtilis (B. subtilis, RCMBA 6005), Staphylococcus aureus (S. aureus, RCMBA 2004), Streptococcus pneumoniae (S. pneumonia, RCMB 000101) as Gram positive bacteria, and Salmonella typhimurium (S. typhimurium, RCMB 000104), and Escherichia coli (E. coli, RCMBA 5003) as Gram negative bacteria have been investigated. The prepared hydrogels showed much higher antimicrobial activities than that of the parent chitosan. The hydrogels were more potent in case of Gram-positive bacteria than Gram-negative bacteria. Increasing the degree of cross-linking in the hydrogels resulted in a weaker antimicrobial activity. PMID:23109847

  10. Synthesis and antimicrobial activity of some novel cross-linked chitosan hydrogels.

    PubMed

    Mohamed, Nadia Ahmed; Fahmy, Mona Mohamed

    2012-01-01

    Four novel hydrogels based on chitosan were synthesized via a cross-linking reaction of chitosan with different concentrations of oxalyl bis 4-(2,5-dioxo-2H-pyrrol- 1(5H)-yl)benzamide. Their structures were confirmed by fourier transform infrared X-ray (FTIR), scanning electron microscopy (SEM) and X-ray diffraction. The antimicrobial activities of the hydrogels against two crop-threatening pathogenic fungi namely: Aspergillus fumigatus (A. fumigatus, RCMBA 06002), and Aspergillus niger (A. niger, RCMBA 06106), and five bacterial species namely: Bacillis subtilis (B. subtilis, RCMBA 6005), Staphylococcus aureus (S. aureus, RCMBA 2004), Streptococcus pneumoniae (S. pneumonia, RCMB 000101) as Gram positive bacteria, and Salmonella typhimurium (S. typhimurium, RCMB 000104), and Escherichia coli (E. coli, RCMBA 5003) as Gram negative bacteria have been investigated. The prepared hydrogels showed much higher antimicrobial activities than that of the parent chitosan. The hydrogels were more potent in case of Gram-positive bacteria than Gram-negative bacteria. Increasing the degree of cross-linking in the hydrogels resulted in a weaker antimicrobial activity.

  11. The GEOSS Science and Technology Stakeholder Network and Service Suite: Linking S&T Communities and GEOSS

    NASA Astrophysics Data System (ADS)

    Plag, Hans-Peter; Jules-Plag, Shelley

    2015-04-01

    The Global Earth Observation System of Systems (GEOSS) developed by the Group on Earth Observations (GEO) aims to provide practice-relevant knowledge in support of decision making in a wide range of societal benefit areas. Generating this practice-relevant knowledge based on Earth observations, socio-economic data and models often depends on research, and utilization of the societal benefits of EOs requires the involvement of science and research communities. Building a GEOSS responding to the needs of a wide range of users necessitates contributions from many science and technology (S&T) communities. In particular, a strong engagement of science and technology (S&T) communities in both the development and use of GEOSS is necessary to address the complex issues associated with the on-going transition out of the Holocene. S&T support is needed to improve interoperability between global observing, modeling, and information systems; to enable data integration across disciplinary boundaries; to facilitate data sharing, archiving, dissemination, and reanalysis; to optimize the recording of observations, assimilation of data into models, and generation of data products; to enhance the value of observations from individual observing systems through their integration in the SBAs; and to harmonize well-calibrated, highly accurate, stable, sustained in-situ and satellite observations of the same variable recorded by different sensors and different agencies. Consequently, the GEO Work Plan includes several Tasks focusing on outreach to S&T communities, and most of the GEO Community of Practice have a strong S&T component. The GEOSS S&T Stakeholder Network facilitates input from S&T communities to GEO. Infrastructure serving and linking S&T users communities and GEOSS has been developed and is integrated into a GEOSS S&T Service Suite (GSTSS). The GSTSS has several outreach components for the demonstration of GEOSS and its value for S&T communities, and for services supporting

  12. Time with friends and physical activity as mechanisms linking obesity and television viewing among youth

    PubMed Central

    2015-01-01

    Background Though bivariate relationships between childhood obesity, physical activity, friendships and television viewing are well documented, empirical assessment of the extent to which links between obesity and television may be mediated by these factors is scarce. This study examines the possibility that time with friends and physical activity are potential mechanisms linking overweight/obesity to television viewing in youth. Methods Data were drawn from children ages 10-18 years old (M = 13.81, SD = 2.55) participating in the 2002 wave of Child Development Supplement (CDS) to the Panel Study of Income Dynamics (PSID) (n = 1,545). Data were collected both directly and via self-report from children and their parents. Path analysis was employed to examine a model whereby the relationships between youth overweight/obesity and television viewing were mediated by time spent with friends and moderate-to-vigorous physical activity (MVPA). Results Overweight/obesity was directly related to less time spent with friends, but not to MVPA. Time spent with friends was directly and positively related to MVPA, and directly and negatively related to time spent watching television without friends. In turn, MVPA was directly and negatively related to watching television without friends. There were significant indirect effects of both overweight/obesity and time with friends on television viewing through MVPA, and of overweight/obesity on MVPA through time with friends. Net of any indirect effects, the direct effect of overweight/obesity on television viewing remained. The final model fit the data extremely well (χ2 = 5.77, df = 5, p<0.0001, RMSEA = 0.01, CFI = 0.99, TLI =0.99). Conclusions We found good evidence that the positive relationships between time with friends and physical activity are important mediators of links between overweight/obesity and television viewing in youth. These findings highlight the importance of moving from examinations of bivariate relationships

  13. Active learning increases student performance in science, engineering, and mathematics.

    PubMed

    Freeman, Scott; Eddy, Sarah L; McDonough, Miles; Smith, Michelle K; Okoroafor, Nnadozie; Jordt, Hannah; Wenderoth, Mary Pat

    2014-06-10

    To test the hypothesis that lecturing maximizes learning and course performance, we metaanalyzed 225 studies that reported data on examination scores or failure rates when comparing student performance in undergraduate science, technology, engineering, and mathematics (STEM) courses under traditional lecturing versus active learning. The effect sizes indicate that on average, student performance on examinations and concept inventories increased by 0.47 SDs under active learning (n = 158 studies), and that the odds ratio for failing was 1.95 under traditional lecturing (n = 67 studies). These results indicate that average examination scores improved by about 6% in active learning sections, and that students in classes with traditional lecturing were 1.5 times more likely to fail than were students in classes with active learning. Heterogeneity analyses indicated that both results hold across the STEM disciplines, that active learning increases scores on concept inventories more than on course examinations, and that active learning appears effective across all class sizes--although the greatest effects are in small (n ≤ 50) classes. Trim and fill analyses and fail-safe n calculations suggest that the results are not due to publication bias. The results also appear robust to variation in the methodological rigor of the included studies, based on the quality of controls over student quality and instructor identity. This is the largest and most comprehensive metaanalysis of undergraduate STEM education published to date. The results raise questions about the continued use of traditional lecturing as a control in research studies, and support active learning as the preferred, empirically validated teaching practice in regular classrooms.

  14. Active learning increases student performance in science, engineering, and mathematics.

    PubMed

    Freeman, Scott; Eddy, Sarah L; McDonough, Miles; Smith, Michelle K; Okoroafor, Nnadozie; Jordt, Hannah; Wenderoth, Mary Pat

    2014-06-10

    To test the hypothesis that lecturing maximizes learning and course performance, we metaanalyzed 225 studies that reported data on examination scores or failure rates when comparing student performance in undergraduate science, technology, engineering, and mathematics (STEM) courses under traditional lecturing versus active learning. The effect sizes indicate that on average, student performance on examinations and concept inventories increased by 0.47 SDs under active learning (n = 158 studies), and that the odds ratio for failing was 1.95 under traditional lecturing (n = 67 studies). These results indicate that average examination scores improved by about 6% in active learning sections, and that students in classes with traditional lecturing were 1.5 times more likely to fail than were students in classes with active learning. Heterogeneity analyses indicated that both results hold across the STEM disciplines, that active learning increases scores on concept inventories more than on course examinations, and that active learning appears effective across all class sizes--although the greatest effects are in small (n ≤ 50) classes. Trim and fill analyses and fail-safe n calculations suggest that the results are not due to publication bias. The results also appear robust to variation in the methodological rigor of the included studies, based on the quality of controls over student quality and instructor identity. This is the largest and most comprehensive metaanalysis of undergraduate STEM education published to date. The results raise questions about the continued use of traditional lecturing as a control in research studies, and support active learning as the preferred, empirically validated teaching practice in regular classrooms. PMID:24821756

  15. Active learning increases student performance in science, engineering, and mathematics

    PubMed Central

    Freeman, Scott; Eddy, Sarah L.; McDonough, Miles; Smith, Michelle K.; Okoroafor, Nnadozie; Jordt, Hannah; Wenderoth, Mary Pat

    2014-01-01

    To test the hypothesis that lecturing maximizes learning and course performance, we metaanalyzed 225 studies that reported data on examination scores or failure rates when comparing student performance in undergraduate science, technology, engineering, and mathematics (STEM) courses under traditional lecturing versus active learning. The effect sizes indicate that on average, student performance on examinations and concept inventories increased by 0.47 SDs under active learning (n = 158 studies), and that the odds ratio for failing was 1.95 under traditional lecturing (n = 67 studies). These results indicate that average examination scores improved by about 6% in active learning sections, and that students in classes with traditional lecturing were 1.5 times more likely to fail than were students in classes with active learning. Heterogeneity analyses indicated that both results hold across the STEM disciplines, that active learning increases scores on concept inventories more than on course examinations, and that active learning appears effective across all class sizes—although the greatest effects are in small (n ≤ 50) classes. Trim and fill analyses and fail-safe n calculations suggest that the results are not due to publication bias. The results also appear robust to variation in the methodological rigor of the included studies, based on the quality of controls over student quality and instructor identity. This is the largest and most comprehensive metaanalysis of undergraduate STEM education published to date. The results raise questions about the continued use of traditional lecturing as a control in research studies, and support active learning as the preferred, empirically validated teaching practice in regular classrooms. PMID:24821756

  16. Characterization of the Enzymatic Activity of the Actin Cross-Linking Domain from the Vibrio cholerae MARTXVc Toxin

    PubMed Central

    Kudryashov, Dmitri S.; Cordero, Christina L.; Reisler, Emil; Fullner Satchell, Karla J.

    2008-01-01

    Vibrio cholerae is a Gram-negative bacterial pathogen that exports enterotoxins which alter host cells through a number of mechanisms resulting in diarrheal disease. Among the secreted toxins is the multifunctional, autoprocessing RTX toxin (MARTXVc), which disrupts actin cytoskeleton by covalently cross-linking actin monomers into oligomers. The region of the toxin responsible for cross-linking activity is the actin cross-linking domain (ACD). In this study, we demonstrate unambiguously that ACD utilizes G- and not F-actin as a substrate for the cross-linking reaction and hydrolyzes one molecule of ATP per cross-linking event. Furthermore, major actin binding proteins that regulate actin cytoskeleton in vivo do not block the cross-linking reaction in vitro. Cofilin inhibits the cross-linking of G- and F-actin at high mole ratio to actin, but accelerates F-actin cross-linking at low mole ratios. DNase I blocks completely the cross-linking of actin, likely due to steric hindrance with one of the cross-linking sites on actin. In the context of the holotoxin, the inhibition of Rho by the Rho-inactivating domain of MARTXVc (Sheahan, K.L., Satchell, K.J.F. 2007 Cellular Microbiology 9:1324-1335) would accelerate F-actin depolymerization and provide G-actin, alone or in complex with actin binding proteins, for cross-linking by ACD, ultimately leading to the observed rapid cell rounding. PMID:17951576

  17. [Activities of Research Institute for Advanced Computer Science

    NASA Technical Reports Server (NTRS)

    Gross, Anthony R. (Technical Monitor); Leiner, Barry M.

    2001-01-01

    The Research Institute for Advanced Computer Science (RIACS) carries out basic research and technology development in computer science, in support of the National Aeronautics and Space Administrations missions. RIACS is located at the NASA Ames Research Center, Moffett Field, California. RIACS research focuses on the three cornerstones of IT research necessary to meet the future challenges of NASA missions: 1. Automated Reasoning for Autonomous Systems Techniques are being developed enabling spacecraft that will be self-guiding and self-correcting to the extent that they will require little or no human intervention. Such craft will be equipped to independently solve problems as they arise, and fulfill their missions with minimum direction from Earth. 2. Human-Centered Computing Many NASA missions require synergy between humans and computers, with sophisticated computational aids amplifying human cognitive and perceptual abilities. 3. High Performance Computing and Networking Advances in the performance of computing and networking continue to have major impact on a variety of NASA endeavors, ranging from modeling and simulation to analysis of large scientific datasets to collaborative engineering, planning and execution. In addition, RIACS collaborates with NASA scientists to apply IT research to a variety of NASA application domains. RIACS also engages in other activities, such as workshops, seminars, visiting scientist programs and student summer programs, designed to encourage and facilitate collaboration between the university and NASA IT research communities.

  18. Learning about Science Graphs and Word Games. Superific Science Book V. A Good Apple Science Activity Book for Grades 5-8+.

    ERIC Educational Resources Information Center

    Conway, Lorraine

    This packet of student materials contains a variety of worksheet activities dealing with science graphs and science word games. These reproducible materials deal with: (1) bar graphs; (2) line graphs; (3) circle graphs; (4) pictographs; (5) histograms; (6) artgraphs; (7) designing your own graphs; (8) medical prefixes; (9) color prefixes; (10)…

  19. Learning about the Human Body. Superific Science Book IV. A Good Apple Science Activity Book for Grades 5-8+.

    ERIC Educational Resources Information Center

    Conway, Lorraine

    Designed to supplement a basic life science or biology program, this document provides teachers with experiential learning activities dealing with the human body. The learning activities vary in the length of time needed for their completion, and require a minimum of equipment and materials. The activities focus on: (1) the human skeleton; (2)…

  20. Microbial Community Dynamics and Activity Link to Indigo Production from Indole in Bioaugmented Activated Sludge Systems

    PubMed Central

    Deng, Jie; Deng, Ye; Van Nostrand, Joy D.; Wu, Liyou; He, Zhili; Qin, Yujia; Zhou, Jiti; Zhou, Jizhong

    2015-01-01

    Biosynthesis of the popular dyestuff indigo from indole has been comprehensively studied using pure cultures, but less has been done to characterize the indigo production by microbial communities. In our previous studies, a wild strain Comamonas sp. MQ was isolated from activated sludge and the recombinant Escherichia coli nagAc carrying the naphthalene dioxygenase gene (nag) from strain MQ was constructed, both of which were capable of producing indigo from indole. Herein, three activated sludge systems, G1 (non-augmented control), G2 (augmented with Comamonas sp. MQ), and G3 (augmented with recombinant E. coli nagAc), were constructed to investigate indigo production. After 132-day operation, G3 produced the highest yields of indigo (99.5 ± 3.0 mg/l), followed by G2 (27.3 ± 1.3 mg/l) and G1 (19.2 ± 1.2 mg/l). The microbial community dynamics and activities associated with indigo production were analyzed by Illumina Miseq sequencing of 16S rRNA gene amplicons. The inoculated strain MQ survived for at least 30 days, whereas E. coli nagAc was undetectable shortly after inoculation. Quantitative real-time PCR analysis suggested the abundance of naphthalene dioxygenase gene (nagAc) from both inoculated strains was strongly correlated with indigo yields in early stages (0–30 days) (P < 0.001) but not in later stages (30–132 days) (P > 0.10) of operation. Based on detrended correspondence analysis (DCA) and dissimilarity test results, the communities underwent a noticeable shift during the operation. Among the four major genera (> 1% on average), the commonly reported indigo-producing populations Comamonas and Pseudomonas showed no positive relationship with indigo yields (P > 0.05) based on Pearson correlation test, while Alcaligenes and Aquamicrobium, rarely reported for indigo production, were positively correlated with indigo yields (P < 0.05). This study should provide new insights into our understanding of indigo bio-production by microbial communities

  1. The Influence of an Activity-Based Explicit Approach on the Turkish Prospective Science Teachers' Conceptions of the Nature of Science

    ERIC Educational Resources Information Center

    Celik, Suat; Bayrakceken, Samih

    2012-01-01

    The aim of this study was to investigate the effect of an activity-based explicit nature of science (NOS) instruction undertaken in the context of a "Science, Technology and Society" course on the prospective science teachers' (PSTs') understandings of NOS. In this course, social science based inquiry activities were used to as a context to lead…

  2. The Role of Entrepreneurial Activities in Academic Pharmaceutical Science Research

    PubMed Central

    Stinchcomb, Audra L.

    2010-01-01

    Academic pharmaceutical science research is expanding further and further from the University setting to encompass the for-profit private company setting. This parallels the National Institutes of Health momentum to include multiple funding opportunities for University and private company collaboration. It has been recognized that the non-profit and for-profit combination research model can accelerate the commercialization of pharmaceutical products, and therefore more efficiently improve human health. Entrepreneurial activities require unique considerations in the University environment, but can be modeled after the commercialization expansion of the academic healthcare enterprise. Challenges and barriers exist to starting a company as an entrepreneurial faculty member, but the rewards to one's personal and professional lives are incomparable. PMID:20017206

  3. The role of entrepreneurial activities in academic pharmaceutical science research.

    PubMed

    Stinchcomb, Audra L

    2010-06-01

    Academic pharmaceutical science research is expanding further and further from the University setting to encompass the for-profit private company setting. This parallels the National Institutes of Health momentum to include multiple funding opportunities for University and private company collaboration. It has been recognized that the nonprofit and for-profit combination research model can accelerate the commercialization of pharmaceutical products, and therefore more efficiently improve human health. Entrepreneurial activities require unique considerations in the University environment, but can be modeled after the commercialization expansion of the academic healthcare enterprise. Challenges and barriers exist to starting a company as an entrepreneurial faculty member, but the rewards to one's personal and professional lives are incomparable. PMID:20017206

  4. VAMP-7 links granule exocytosis to actin reorganization during platelet activation.

    PubMed

    Koseoglu, Secil; Peters, Christian G; Fitch-Tewfik, Jennifer L; Aisiku, Omozuanvbo; Danglot, Lydia; Galli, Thierry; Flaumenhaft, Robert

    2015-07-30

    Platelet activation results in profound morphologic changes accompanied by release of granule contents. Recent evidence indicates that fusion of granules with the plasma membrane during activation provides auxiliary membrane to cover growing actin structures. Yet little is known about how membrane fusion is coupled with actin reorganization. Vesicle-associated membrane protein (VAMP)-7 is found on platelet vesicles and possesses an N-terminal longin domain capable of linking exocytosis to cytoskeletal remodeling. We have evaluated platelets from VAMP-7(-/-) mice to determine whether this VAMP isoform contributes to granule release and platelet spreading. VAMP-7(-/-) platelets demonstrated a partial defect in dense granule exocytosis and impaired aggregation. α Granule exocytosis from VAMP-7(-/-) platelets was diminished both in vitro and in vivo during thrombus formation. Consistent with a role of VAMP-7 in cytoskeletal remodeling, spreading on matrices was decreased in VAMP-7(-/-) platelets compared to wild-type controls. Immunoprecipitation of VAMP-7 revealed an association with VPS9-domain ankyrin repeat protein (VARP), an adaptor protein that interacts with both membrane-bound and cytoskeleton proteins and with Arp2/3. VAMP-7, VARP, and Arp2/3 localized to the platelet periphery during spreading. These studies demonstrate that VAMP-7 participates in both platelet granule secretion and spreading and suggest a mechanism whereby VAMP-7 links granule exocytosis with actin reorganization. PMID:25999457

  5. VAMP-7 links granule exocytosis to actin reorganization during platelet activation.

    PubMed

    Koseoglu, Secil; Peters, Christian G; Fitch-Tewfik, Jennifer L; Aisiku, Omozuanvbo; Danglot, Lydia; Galli, Thierry; Flaumenhaft, Robert

    2015-07-30

    Platelet activation results in profound morphologic changes accompanied by release of granule contents. Recent evidence indicates that fusion of granules with the plasma membrane during activation provides auxiliary membrane to cover growing actin structures. Yet little is known about how membrane fusion is coupled with actin reorganization. Vesicle-associated membrane protein (VAMP)-7 is found on platelet vesicles and possesses an N-terminal longin domain capable of linking exocytosis to cytoskeletal remodeling. We have evaluated platelets from VAMP-7(-/-) mice to determine whether this VAMP isoform contributes to granule release and platelet spreading. VAMP-7(-/-) platelets demonstrated a partial defect in dense granule exocytosis and impaired aggregation. α Granule exocytosis from VAMP-7(-/-) platelets was diminished both in vitro and in vivo during thrombus formation. Consistent with a role of VAMP-7 in cytoskeletal remodeling, spreading on matrices was decreased in VAMP-7(-/-) platelets compared to wild-type controls. Immunoprecipitation of VAMP-7 revealed an association with VPS9-domain ankyrin repeat protein (VARP), an adaptor protein that interacts with both membrane-bound and cytoskeleton proteins and with Arp2/3. VAMP-7, VARP, and Arp2/3 localized to the platelet periphery during spreading. These studies demonstrate that VAMP-7 participates in both platelet granule secretion and spreading and suggest a mechanism whereby VAMP-7 links granule exocytosis with actin reorganization.

  6. VAMP-7 links granule exocytosis to actin reorganization during platelet activation

    PubMed Central

    Koseoglu, Secil; Peters, Christian G.; Fitch-Tewfik, Jennifer L.; Aisiku, Omozuanvbo; Danglot, Lydia; Galli, Thierry

    2015-01-01

    Platelet activation results in profound morphologic changes accompanied by release of granule contents. Recent evidence indicates that fusion of granules with the plasma membrane during activation provides auxiliary membrane to cover growing actin structures. Yet little is known about how membrane fusion is coupled with actin reorganization. Vesicle-associated membrane protein (VAMP)-7 is found on platelet vesicles and possesses an N-terminal longin domain capable of linking exocytosis to cytoskeletal remodeling. We have evaluated platelets from VAMP-7−/− mice to determine whether this VAMP isoform contributes to granule release and platelet spreading. VAMP-7−/− platelets demonstrated a partial defect in dense granule exocytosis and impaired aggregation. α Granule exocytosis from VAMP-7−/− platelets was diminished both in vitro and in vivo during thrombus formation. Consistent with a role of VAMP-7 in cytoskeletal remodeling, spreading on matrices was decreased in VAMP-7−/− platelets compared to wild-type controls. Immunoprecipitation of VAMP-7 revealed an association with VPS9-domain ankyrin repeat protein (VARP), an adaptor protein that interacts with both membrane-bound and cytoskeleton proteins and with Arp2/3. VAMP-7, VARP, and Arp2/3 localized to the platelet periphery during spreading. These studies demonstrate that VAMP-7 participates in both platelet granule secretion and spreading and suggest a mechanism whereby VAMP-7 links granule exocytosis with actin reorganization. PMID:25999457

  7. Thylakoid Membrane Maturation and PSII Activation Are Linked in Greening Synechocystis sp. PCC 6803 Cells1

    PubMed Central

    Barthel, Sandra; Bernát, Gábor; Seidel, Tobias; Rupprecht, Eva; Kahmann, Uwe; Schneider, Dirk

    2013-01-01

    Thylakoid membranes are typical and essential features of both chloroplasts and cyanobacteria. While they are crucial for phototrophic growth of cyanobacterial cells, biogenesis of thylakoid membranes is not well understood yet. Dark-grown Synechocystis sp. PCC 6803 cells contain only rudimentary thylakoid membranes but still a relatively high amount of phycobilisomes, inactive photosystem II and active photosystem I centers. After shifting dark-grown Synechocystis sp. PCC 6803 cells into the light, “greening” of Synechocystis sp. PCC 6803 cells, i.e. thylakoid membrane formation and recovery of photosynthetic electron transport reactions, was monitored. Complete restoration of a typical thylakoid membrane system was observed within 24 hours after an initial lag phase of 6 to 8 hours. Furthermore, activation of photosystem II complexes and restoration of a functional photosynthetic electron transport chain appears to be linked to the biogenesis of organized thylakoid membrane pairs. PMID:23922268

  8. Activation-Induced Cytidine Deaminase Links Ovulation-Induced Inflammation and Serous Carcinogenesis.

    PubMed

    Sapoznik, Stav; Bahar-Shany, Keren; Brand, Hadar; Pinto, Yishay; Gabay, Orshay; Glick-Saar, Efrat; Dor, Chen; Zadok, Oranit; Barshack, Iris; Zundelevich, Adi; Gal-Yam, Einav Nili; Yung, Yuval; Hourvitz, Ariel; Korach, Jacob; Beiner, Mario; Jacob, Jasmine; Levanon, Erez Y; Barak, Michal; Aviel-Ronen, Sarit; Levanon, Keren

    2016-02-01

    In recent years, the notion that ovarian carcinoma results from ovulation-induced inflammation of the fallopian tube epithelial cells (FTECs) has gained evidence. However, the mechanistic pathway for this process has not been revealed yet. In the current study, we propose the mutator protein activation-induced cytidine deaminase (AID) as a link between ovulation-induced inflammation in FTECs and genotoxic damage leading to ovarian carcinogenesis. We show that AID, previously shown to be functional only in B lymphocytes, is expressed in FTECs under physiological conditions, and is induced in vitro upon ovulatory-like stimulation and in vivo in carcinoma-associated FTECs. We also report that AID activity results in epigenetic, genetic and genomic damage in FTECs. Overall, our data provides new insights into the etiology of ovarian carcinogenesis and may set the ground for innovative approaches aimed at prevention and early detection. PMID:26936395

  9. Spontaneous regional brain activity links restrained eating to later weight gain among young women.

    PubMed

    Dong, Debo; Jackson, Todd; Wang, Yulin; Chen, Hong

    2015-07-01

    Theory and prospective studies have linked restrained eating (RE) to risk for future weight gain and the onset of obesity, but little is known about resting state neural activity that may underlie this association. To address this gap, resting fMRI was used to test the extent to which spontaneous neural activity in regions associated with inhibitory control and food reward account for potential relations between baseline RE levels and changes in body weight among dieters over a one-year interval. Spontaneous regional activity patterns corresponding to RE were assessed among 50 young women using regional homogeneity (ReHo) analysis, which measured temporal synchronization of spontaneous fluctuations within a food deprivation condition. Analyses indicated higher baseline RE scores predicted more weight gain at a one-year follow-up. Furthermore, food-deprived dieting women with high dietary restraint scores exhibited more spontaneous local activity in brain regions associated with the expectation and valuation for food reward [i.e., orbitofrontal cortex (OFC)/ventromedial prefrontal cortex (VMPFC)] and reduced spontaneous local activity in inhibitory control regions [i.e., bilateral dorsal-lateral prefrontal cortex (DLPFC)] at baseline. Notably, the association between baseline RE and follow-up weight gain was mediated by decreased local synchronization of the right DLPFC in particular and, to a lesser degree, increased local synchronization of the right VMPFC. In conjunction with previous research, these findings highlight possible neural mechanisms underlying the relation between RE and risk for weight gain. PMID:26004091

  10. Spontaneous regional brain activity links restrained eating to later weight gain among young women.

    PubMed

    Dong, Debo; Jackson, Todd; Wang, Yulin; Chen, Hong

    2015-07-01

    Theory and prospective studies have linked restrained eating (RE) to risk for future weight gain and the onset of obesity, but little is known about resting state neural activity that may underlie this association. To address this gap, resting fMRI was used to test the extent to which spontaneous neural activity in regions associated with inhibitory control and food reward account for potential relations between baseline RE levels and changes in body weight among dieters over a one-year interval. Spontaneous regional activity patterns corresponding to RE were assessed among 50 young women using regional homogeneity (ReHo) analysis, which measured temporal synchronization of spontaneous fluctuations within a food deprivation condition. Analyses indicated higher baseline RE scores predicted more weight gain at a one-year follow-up. Furthermore, food-deprived dieting women with high dietary restraint scores exhibited more spontaneous local activity in brain regions associated with the expectation and valuation for food reward [i.e., orbitofrontal cortex (OFC)/ventromedial prefrontal cortex (VMPFC)] and reduced spontaneous local activity in inhibitory control regions [i.e., bilateral dorsal-lateral prefrontal cortex (DLPFC)] at baseline. Notably, the association between baseline RE and follow-up weight gain was mediated by decreased local synchronization of the right DLPFC in particular and, to a lesser degree, increased local synchronization of the right VMPFC. In conjunction with previous research, these findings highlight possible neural mechanisms underlying the relation between RE and risk for weight gain.

  11. Direct evidence of complement activation in HELLP syndrome: A link to atypical hemolytic uremic syndrome.

    PubMed

    Vaught, Arthur J; Gavriilaki, Eleni; Hueppchen, Nancy; Blakemore, Karin; Yuan, Xuan; Seifert, Sara M; York, Sarah; Brodsky, Robert A

    2016-05-01

    HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets) is a severe variant of pre-eclampsia whose pathogenesis remains unclear. Recent evidence and clinical similarities suggest a link to atypical hemolytic uremic syndrome, a disease of excessive activation of the alternative complement pathway effectively treated with a complement inhibitor, eculizumab. Therefore, we used a functional complement assay, the modified Ham test, to analyze sera of women with classic or atypical HELLP syndrome, pre-eclampsia with severe features, normal pregnancies, and healthy nonpregnant women. Sera were also evaluated using levels of the terminal product of complement activation (C5b-9). We tested the in vitro ability of eculizumab to inhibit complement activation in HELLP serum. Increased complement activation was observed in participants with classic or atypical HELLP compared with those with normal pregnancies and nonpregnant controls. Mixing HELLP serum with eculizumab-containing serum resulted in a significant decrease in cell killing compared with HELLP serum alone. We found that HELLP syndrome is associated with increased complement activation as assessed with the modified Ham test. This assay may aid in the diagnosis of HELLP syndrome and could confirm that its pathophysiology is related to that of atypical hemolytic uremic syndrome.

  12. [Research activities in applied mathematics, fluid mechanics, and computer science

    NASA Technical Reports Server (NTRS)

    1995-01-01

    This report summarizes research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, fluid mechanics, and computer science during the period April 1, 1995 through September 30, 1995.

  13. More Science Activities. 20 Exciting Experiments To Do!

    ERIC Educational Resources Information Center

    Smithsonian Institution, Washington, DC.

    Science and technology affect every facet of human life. By the 21st century, society will demand that all of its citizens possess basic competencies in the fundamentals of science and the use of technology. As science increasingly becomes the dominant subject of the work place, it is important to begin developing within children an understanding…

  14. Taking Science Home: Connecting Schools and Families through Science Activity Packs for Young Children

    ERIC Educational Resources Information Center

    Reinhart, Meredith; Bloomquist, Debra; Strickler-Eppard, Lacey; Czerniak, Charlene M.; Gilbert, Amanda; Kaderavek, Joan; Molitor, Scott C.

    2016-01-01

    A Framework for K-12 Science Education indicates that introducing young children to scientific and engineering practices, core disciplinary ideas, and crosscutting concepts during the early years is essential for the development of conceptual understanding in science. Unfortunately, science is infrequently included in preschool and primary…

  15. Disulfide cross-linking influences symbiotic activities of nodule peptide NCR247.

    PubMed

    Shabab, Mohammed; Arnold, Markus F F; Penterman, Jon; Wommack, Andrew J; Bocker, Hartmut T; Price, Paul A; Griffitts, Joel S; Nolan, Elizabeth M; Walker, Graham C

    2016-09-01

    Interactions of rhizobia with legumes establish the chronic intracellular infection that underlies symbiosis. Within nodules of inverted repeat-lacking clade (IRLC) legumes, rhizobia differentiate into nitrogen-fixing bacteroids. This terminal differentiation is driven by host nodule-specific cysteine-rich (NCR) peptides that orchestrate the adaptation of free-living bacteria into intracellular residents. Medicago truncatula encodes a family of >700 NCR peptides that have conserved cysteine motifs. NCR247 is a cationic peptide with four cysteines that can form two intramolecular disulfide bonds in the oxidized forms. This peptide affects Sinorhizobium meliloti transcription, translation, and cell division at low concentrations and is antimicrobial at higher concentrations. By preparing the three possible disulfide-cross-linked NCR247 regioisomers, the reduced peptide, and a variant lacking cysteines, we performed a systematic study of the effects of intramolecular disulfide cross-linking and cysteines on the activities of an NCR peptide. The relative activities of the five NCR247 variants differed strikingly among the various bioassays, suggesting that the NCR peptide-based language used by plants to control the development of their bacterial partners during symbiosis is even greater than previously recognized. These patterns indicate that certain NCR bioactivities require cysteines whereas others do not. The results also suggest that NCR247 may exert some of its effects within the cell envelope whereas other activities occur in the cytoplasm. BacA, a membrane protein that is critical for symbiosis, provides protection against all bactericidal forms of NCR247. Oxidative folding protects NCR247 from degradation by the symbiotically relevant metalloprotease HrrP (host range restriction peptidase), suggesting that disulfide bond formation may additionally stabilize NCR peptides during symbiosis. PMID:27551097

  16. Archive & Data Management Activities for ISRO Science Archives

    NASA Astrophysics Data System (ADS)

    Thakkar, Navita; Moorthi, Manthira; Gopala Krishna, Barla; Prashar, Ajay; Srinivasan, T. P.

    2012-07-01

    . For other AO payloads users can view the metadata and the data is available through FTP site. This same archival and dissemination strategy will be extended for the next moon mission Chandrayaan-2. ASTROSAT is going to be the first multi-wavelength astronomical mission for which the data is archived at ISSDC. It consists of five astronomical payloads that would allow simultaneous multi-wavelengths observations from X-ray to Ultra-Violet (UV) of astronomical objects. It is planned to archive the data sets in FITS. The archive of the ASTROSAT will be done in the Archive Layer at ISSDC. The Browse of the Archive will be available through the ISDA (Indian Science Data Archive) web site. The Browse will be IVOA compliant with a search mechanism using VOTable. The data will be available to the users only on request basis via a FTP site after the lock in period is over. It is planned that the Level2 pipeline software and various modules for processing the data sets will be also available on the web site. This paper, describes the archival procedure of Chandrayaan-1 and archive plan for the ASTROSAT, Chandrayaan-2 and other future mission of ISRO including the discussion on data management activities.

  17. Enhanced esterification activity through interfacial activation and cross-linked immobilization mechanism of Rhizopus oryzae lipase in a nonaqueous medium.

    PubMed

    Kartal, Funda

    2016-07-01

    Interfacial activation via surfactant (Tween 80, Triton X-100) treatment was conducted to improve the esterification activity of Rhizopus oryzae lipase that had undergone immobilization through cross-linked enzyme aggregates (CLEA®) technique. Surfactant pretreated immobilized enzymes exhibited better esterification activity compared to free and non-pretreated immobilized enzyme (Control CLEAs) since higher conversion rates were obtained within shorter times. The superiority of surfactant pretreated CLEAs, especially Tween 80 pretreated CLEAs (T 80 PT CLEAs), were clearly pronounced when longer alcohols were used as substrates. Conversion values exceeded 90% for octyl octanoate, oleyl octanoate and oleyl oleate synthesis with T 80 PT CLEAs whereas Control CLEAs and free enzyme showed no activity. Maximum conversions were achieved in the case equal molars of the substrates or in the case excess of the alcohol to acid in cyclohexane. In solvent free medium containing equal molars of substrates the conversion rates were 85% and 87% with T 80 PT CLEAs respectively for octyl octanoate and oleyl oleate within 2 hours. T 80 PT CLEAs showed 59% of its original activity after 7 consecutive usage for oleyl oleate synthesis. © 2016 American Institute of Chemical Engineers Biotechnol. Prog., 32:899-904, 2016. PMID:27111483

  18. Intracellular pathways linking hypoxia to activation of c-fos and AP-1.

    PubMed

    Premkumar, D R; Adhikary, G; Overholt, J L; Simonson, M S; Cherniack, N S; Prabhakar, N R

    2000-01-01

    Organisms respond to hypoxia through detection of blood oxygen levels by sensors at peripheral chemoreceptors and by receptors in certain key cells of the body. The pathways over which peripheral chemoreceptor signals are transmitted to respiratory muscles are well established. However, the intracellular pathways that transmit hypoxic stimulus to gene activation are just being identified. Using anti-sense c-fos strategy, we have shown that c-fos is essential for the activation of activator protein-1 transcription factor complex (AP-1) and subsequent stimulation of downstream genes such as tyrosine hydroxylase (TH; Mishra et al. 1998). The purpose of the present study was to identify intracellular pathways that link hypoxia to activation of c-fos. The results of the present study show that hypoxia causes Ca2+ influx through L-type voltage gated Ca2+ channels and that hypoxia-induced c-fos gene expression is Ca2+/calmodulin dependent. We also demonstrate that hypoxia activates the extracellular-regulated kinase (ERK) and p38, but not JNK. Further, phosphorylation of ERK is essential for c-fos activation via SRE cis-element. Further characterization of nuclear signalling pathways provides evidence for the involvement of Src, a non receptor protein tyrosine kinase, and Ras, a small G protein, in the hypoxia-induced c-fos gene expression. These results suggest a possible role for non-receptor protein tyrosine kinases in propagating signals from G-protein coupled receptors to the activation of immediate early genes such as c-fos during hypoxia.

  19. Preparation, characterization, and antifungal activity of hymexazol-linked chitosan derivatives

    NASA Astrophysics Data System (ADS)

    Li, Yan; Qin, Yukun; Liu, Song; Li, Pengcheng; Xing, Rong'e.

    2016-09-01

    In this study, three hymexazol-linked chitosan derivatives (HML-CS) were synthesized and their structures confirmed by Fourier transform infrared and elemental analysis. Linkage ratios were measured by high performance liquid chromatography. The derivatives' antifungal activity against the plant pathogenic fungi Rhizoctonia solani CGMCC 3.28 and Gibberella zeae CGMCC 3.42 were investigated at concentrations of 100, 200, and 400 mg/L. These HML-CS derivatives exhibited stronger antifungal activity than CS alone. HML-CS-1 showed the best antifungal activity against G. zeae, whose antifungal index was 65.9% at 400 mg/L, and also showed the best antifungal activity against R. solani, whose antifungal index was 52.7% at 400 mg/L. This conjugation of CS and HML suggested the presence of synergistic effects between the moieties and indicated that these derivatives possessed great potential as novel fungicides and require further research for the development of applications in crop protection.

  20. Children's Literature with a Science Emphasis: Twenty Teacher-Developed K-8 Activity Packets.

    ERIC Educational Resources Information Center

    Butler, Malcolm B.

    This document features 10 science activity packets developed for elementary students by science teachers in a graduate seminar. The activity packets were designed to cover existing commercial children's books on specific content areas. The 10 activity packets are: (1) "Bringing the Rain to Kapiti Plain," which explains the water cycle; (2)…

  1. Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin

    PubMed Central

    Liu, Haiyang; Li, Jianchao; Raval, Manmeet H; Yao, Ningning; Deng, Xiaoying; Lu, Qing; Nie, Si; Feng, Wei; Wan, Jun; Yengo, Christopher M; Liu, Wei; Zhang, Mingjie

    2016-01-01

    Class III myosins (Myo3) and actin-bundling protein Espin play critical roles in regulating the development and maintenance of stereocilia in vertebrate hair cells, and their defects cause hereditary hearing impairments. Myo3 interacts with Espin1 through its tail homology I motif (THDI), however it is not clear how Myo3 specifically acts through Espin1 to regulate the actin bundle assembly and stabilization. Here we discover that Myo3 THDI contains a pair of repeat sequences capable of independently and strongly binding to the ankyrin repeats of Espin1, revealing an unexpected Myo3-mediated cross-linking mechanism of Espin1. The structures of Myo3 in complex with Espin1 not only elucidate the mechanism of the binding, but also reveal a Myo3-induced release of Espin1 auto-inhibition mechanism. We also provide evidence that Myo3-mediated cross-linking can further promote actin fiber bundling activity of Espin1. DOI: http://dx.doi.org/10.7554/eLife.12856.001 PMID:26785147

  2. Peroxisome proliferator-activated receptor agonists modulate neuropathic pain: a link to chemokines?

    PubMed Central

    Freitag, Caroline M.; Miller, Richard J.

    2014-01-01

    Chronic pain presents a widespread and intractable medical problem. While numerous pharmaceuticals are used to treat chronic pain, drugs that are safe for extended use and highly effective at treating the most severe pain do not yet exist. Chronic pain resulting from nervous system injury (neuropathic pain) is common in conditions ranging from multiple sclerosis to HIV-1 infection to type II diabetes. Inflammation caused by neuropathy is believed to contribute to the generation and maintenance of neuropathic pain. Chemokines are key inflammatory mediators, several of which (MCP-1, RANTES, MIP-1α, fractalkine, SDF-1 among others) have been linked to chronic, neuropathic pain in both human conditions and animal models. The important roles chemokines play in inflammation and pain make them an attractive therapeutic target. Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors known for their roles in metabolism. Recent research has revealed that PPARs also play a role in inflammatory gene repression. PPAR agonists have wide-ranging effects including inhibition of chemokine expression and pain behavior reduction in animal models. Experimental evidence suggests a connection between the pain ameliorating effects of PPAR agonists and suppression of inflammatory gene expression, including chemokines. In early clinical research, one PPARα agonist, palmitoylethanolamide (PEA), shows promise in relieving chronic pain. If this link can be better established, PPAR agonists may represent a new drug therapy for neuropathic pain. PMID:25191225

  3. Students' Representations of Scientific Practice during a Science Internship: Reflections from an Activity-Theoretic Perspective

    ERIC Educational Resources Information Center

    Hsu, Pei-Ling; van Eijck, Michiel; Roth, Wolff-Michael

    2010-01-01

    Working at scientists' elbows is one suggestion that educators make to improve science education, because such "authentic experiences" provide students with various types of science knowledge. However, there is an ongoing debate in the literature about the assumption that authentic science activities can enhance students' understandings of…

  4. Differentiated Instruction for K-8 Math and Science: Activities and Lesson Plans

    ERIC Educational Resources Information Center

    Hamm, Mary; Adams, Dennis

    2008-01-01

    This book offers practical recommendations to reach every student in a K-8 classroom. Research-based and written in a teacher-friendly style, it will help teachers with classroom organization and lesson planning in math and science. Included are math and science games, activities, ideas, and lesson plans based on the math and science standards.…

  5. Public Understanding of Science. Summary of Grants and Activities 1976-1981.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC.

    The Public Understanding of Science Program (PUOS) was formed in 1957 to help improve popular awareness and understanding of the role, activities, methods, and implications of science. The first section of this document highlights the role and purpose of the PUOS program, summarizing the need for informal science education, PUOS strategy, the…

  6. Developing Preservice Science Teachers' Self-Determined Motivation toward Environment through Environmental Activities

    ERIC Educational Resources Information Center

    Karaarslan, Guliz; Sungur, Semra; Ertepinar, Hamide

    2014-01-01

    The aim of this study was to develop pre-service science teachers' self-determined motivation toward environment before, after and five months following the environmental course activities guided by self-determination theory. The sample of the study was 33 pre-service science teachers who participated in an environmental science course. This…

  7. 76 FR 57762 - Agency Information Collection Activities: Proposed New Collection-Social Science Assessment and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ... National Park Service Agency Information Collection Activities: Proposed New Collection--Social Science... INFORMATION: OMB Control Number: 1024-NEW. Title: Social Science Assessment and Geographic Analysis of Marine.... Loomis, Ph.D. Institute for Coastal Science and Policy, Mail Stop 250, Flanagan, East Carolina...

  8. Development of an Accelerometer-Linked Online Intervention System to Promote Physical Activity in Adolescents

    PubMed Central

    Guthrie, Nicole; Bradlyn, Andrew; Thompson, Sharon K.; Yen, Sophia; Haritatos, Jana; Dillon, Fred; Cole, Steve W.

    2015-01-01

    Most adolescents do not achieve the recommended levels of moderate-to-vigorous physical activity (MVPA), placing them at increased risk for a diverse array of chronic diseases in adulthood. There is a great need for scalable and effective interventions that can increase MVPA in adolescents. Here we report the results of a measurement validation study and a preliminary proof-of-concept experiment testing the impact of Zamzee, an accelerometer-linked online intervention system that combines proximal performance feedback and incentive motivation features to promote MVPA. In a calibration study that parametrically varied levels of physical activity in 31 12-14 year-old children, the Zamzee activity meter was shown to provide a valid measure of MVPA (sensitivity in detecting MVPA = 85.9%, specificity = 97.5%, and r = .94 correspondence with the benchmark RT3 accelerometer system; all p < .0001). In a subsequent randomized controlled multi-site experiment involving 182 middle school-aged children assessed for MVPA over 6 wks, intent-to-treat analyses found that those who received access to the Zamzee intervention had average MVPA levels 54% greater than those of a passive control group (p < 0.0001) and 68% greater than those of an active control group that received access to a commercially available active videogame (p < .0001). Zamzee’s effects on MVPA did not diminish significantly over the course of the 6-wk study period, and were statistically significant in both females and males, and in normal- vs. high-BMI subgroups. These results provide promising initial indications that combining the Zamzee activity meter with online proximal performance feedback and incentive motivation features can positively impact MVPA levels in adolescents. PMID:26010359

  9. Temporal link between plasma thyrotropin levels and electroencephalographic activity in man.

    PubMed

    Gronfier, C; Luthringer, R; Follenius, M; Schaltenbrand, N; Macher, J P; Muzet, A; Brandenberger, G

    1995-11-17

    Plasma thyrotropin (TSH) levels have been previously shown to be associated with the internal sleep structure determined by conventional scoring of sleep stages. This temporal relationship was re-evaluated using spectral analysis of the sleep electroencephalogram (EEG). Eight healthy male subjects underwent two randomized night studies after having received either placebo or 5 mg ritanserin, a selective 5-HT2 receptor antagonist known to increase slow-wave sleep. Delta relative power and TSH levels, determined at 10 min intervals, were found to be inversely related with an average cross-correlation coefficient highly significant (P < 0.0001) in both experimental conditions. Alpha slow-wave index, an estimator of awakenings, and TSH pulses exhibited a significant temporal association in both conditions. These results demonstrate that TSH fluctuations are linked to the sleep EEG activity in man.

  10. Black Box Activities for Grades Seven-Nine Science Programs and Beyond. A Supplement for Science 1, 2, &3.

    ERIC Educational Resources Information Center

    Schlenker, Richard M., Comp.

    Many times science does not provide us with exact descriptions of phenomena or answers to questions but only allows us to make educated guesses. Black box activities encourage this method of scientific thinking because the activity is performed inside a sealed container requiring the students to hypothesize on the contents and operation of the…

  11. Learning about Animals. Superific Science Book III. A Good Apple Science Activity Book for Grades 5-8+.

    ERIC Educational Resources Information Center

    Conway, Lorraine

    Designed to arouse interest in students about animals, this document was developed to provide teachers with a variety of information and teaching activities. The booklet is intended to enable students to become knowledgeable about science concepts relating to animals without the use of expensive equipment. The teaching activities deal with: (1)…

  12. KUSPACE: Embedding Science Technology and Mathematics Ambassador Activities in the Undergradiuate Engineering Curriculum

    NASA Astrophysics Data System (ADS)

    Welch, C.; Osborne, B.

    The UK national STEM Ambassadors programme provides inspiring role models for school students in science, technology, engineering, mathematics (STEM) subjects. STEMNET, the national body responsible for STEM Ambassa- dors aims to provide more than 27,000 STEM Ambassadors nationwide by the end of 2011. This paper reports on a project at Kingston University to embed STEM Ambassador training and activity in Year 2 of the undergraduate Aerospace Engineering, Astronautics and Space Technology degree. The project, known as KUSPACE (Kingston University Students Providing Amazing Classroom Experiences), was conceived to develop students' communication, planning and presentation skills and build links between different cohort years, while providing a valuable contribution to local primary schools' STEM programmes and simultaneously raising the public engagement profile of the university. This paper describes the pedagogical conception of the KUSPACE, its implementation in the curriculum, the delivery of it in the university and schools and its effect on the undergraduate students, as well as identifying good practice and drawing attention to lessons learned.STEMNET (www.stemnet.org) is the UK's Science, Technol- ogy, Engineering and Mathematics Network. Working with a broad range of UK partners and funded by the UK govern- ment's Department for Business Innovation and Skills, STEMNET plays a significant role in ensuring that five to nineteen year olds and their teachers can experience a wide range of activities and schemes which enhance and enrich the school curriculum [1]. Covering all aspects of Science, Tech- nology, Engineering and Maths (STEM), these activities and schemes are designed both to increase STEM awareness and literacy in the young people and also to encourage more of them to undertake post-16 STEM qualifications and associated careers [2]. STEMNET operates through forty-five local con- tract holders around the UK which help the network deliver its

  13. Physics and Science Education through Project Activities of University Students and Regional Collaboration

    NASA Astrophysics Data System (ADS)

    Hasegawa, Makoto

    A project team "Rika-Kobo" organized by university students has actively performed various science education activities at primary and secondary schools and other educational facilities as well as in science events in local areas. The activities of this student project team are related to various fields of physics and sciences. In order to provide more attractive activities, the student members prepare original experiment tools and easily-understandable presentation and explanation. Through such activities, the members can have opportunities of obtaining new knowledge and refreshing their already-obtained understandings in related fields of physics and sciences. They can also have chances of improving their skills and abilities such as presentation, problem-finding and solving, which are useful for realizing their career development. The activities of the student project team have been also welcomed by children, parents, teachers and other people in local areas because the activities provide them with opportunities of knowing and learning new knowledge in physics and sciences.

  14. Integrin-linked kinase activity modulates the pro-metastatic behavior of ovarian cancer cells

    PubMed Central

    Bruney, Lana; Liu, Yueying; Grisoli, Anne; Ravosa, Matthew J.; Stack, M. Sharon

    2016-01-01

    Epithelial ovarian cancer (EOC) is the most fatal gynecologic cancer in the U.S., resulting in >14,000 deaths/year. Most women are diagnosed at late stage with widely disseminated intra-peritoneal metastatic disease, resulting in a 5-year survival rate of <30%. EOCs spread via direct extension and exfoliation into the peritoneal cavity, adhesion to peritoneal mesothelial cells, mesothelial cell retraction to expose sub-mseothelial matrix and anchoring in the type I collagen-rich matrix to generate secondary lesions. As a molecular-level understanding of EOC metastasis may identify novel therapeutic targets, the current study evaluated the expression and activity of integrin-linked kinase (ILK), a Ser/Thr protein kinase activated upon integrin-mediated adhesion. Results show that ILK is co-expressed in EOC with the pro-metastatic enzyme membrane type 1 matrix metalloproteinase (MT1-MMP) and catalyzed phosphorylation of the cytoplasmic tail of the proteinase. Downregulation of ILK expression or activity reduced adhesion to and invasion of collagen gels and organotypic meso-mimetic cultures. As an initial early event in EOC metastasis is integrin-mediated adhesion, these results suggest that further evaluation of ILK inhibitors as anti-metastatic agents in EOC is warranted. PMID:26959113

  15. Linking nutrition and behavioural dominance: carbohydrate scarcity limits aggression and activity in Argentine ants.

    PubMed

    Grover, Crystal D; Kay, Adam D; Monson, Jessica A; Marsh, Thomas C; Holway, David A

    2007-12-01

    Predicting the outcome of competitive interactions is a fundamental goal in ecology. Ecological stoichiometry, which relates nutrient balance to ecological processes, provides a framework for identifying mechanistic links among macronutrient availability, nutritional physiology and competitive performance. Because carbohydrates serve as a principal metabolic fuel, carbohydrate scarcity may impinge upon behaviours affecting competitive dominance (e.g. aggression, activity) to a greater extent than deficiencies of protein or other nutrients used preferentially for growth. Here, we tested this prediction with a diet manipulation study involving laboratory colonies of Argentine ants (Linepithema humile), a widespread and aggressive invasive species. The availability of both sucrose and insect prey influenced brood production and worker survival after three months. However, colonies became less aggressive and less active only when deprived of sucrose (but not prey). Scarcity of sucrose (but not prey) was also associated with reduced fat mass in individual workers. These data provide the first experimental support that carbohydrate scarcity compromises aggression and activity in ants, and illustrate, in principle, how access to carbohydrate-rich resources (e.g. plant exudates, hemipteran honeydew) might influence behavioural investments that contribute to competitive performance. Such investments might be especially important for invasive ants, given their aggressiveness and tendency to interact with honeydew-producing Hemiptera.

  16. Subchronic exposure to leachate activates key markers linked with neurological disorder in Wistar male rat.

    PubMed

    Akintunde, J K; Oboh, G

    2015-12-01

    The linking of various environmental chemicals exposure to neurodegenerative disorders is current. This study was undertaken to elucidate the toxic effects and the underlying biochemical mechanism of leachate obtained from Elewi Odo municipal battery recycling site (EOMABRL) using key markers of neuronal damage in rat via an oral route. Analysis of the concentrations of heavy metals showed that lead, cadmium, nickel, chromium, manganese, and iron were higher than the acceptable limits set by the regulatory authority-the World Health Organization. Whereas, copper, zinc, and cobalt were lower than permissible limits. EOMABRL was administered at 0, 20, 40, 60, 80, and 100% concentrations to adult male rats for 60 days. An in vitro study was also carried out in the cerebellum to assess cholinesterase biochemistry assays. Following exposure, brain was collected to determine the antioxidant status. EOMABRL administration significantly increased superoxide dismutase (SOD) and catalase (CAT) activities, and a sequential decrease in reduced glutathione (GSH) level with a concomitant increase in the accumulation of hydrogen peroxide (H2O2) and malondialdehyde (MDA) level was observed, when compared with the control. The treated rat had a significant (P < 0.05) increase in the activities of acetycholinesterase (AChE) and butyrylcholinesterase (BuChE). Taken together, these findings conclude that some possible mechanisms by which EOMABRL elicits neuronal disorder in male rat could be through the activation of AChE and BuChE and induction of oxidative stress with necrosis of neuronal cells. PMID:26362636

  17. Food Science. Content Modules for Food Science Featuring Problem-Solving Activities in Family and Consumer Sciences.

    ERIC Educational Resources Information Center

    Roff, Lori; Stringer, Lola

    The food science course developed in Missouri combines basic scientific and mathematics principles in a hands-on instructional format as a part of the family and consumer sciences education curriculum. Throughout the course, students conduct controlled experiments and use scientific laboratory techniques and information to explore the biological…

  18. Lorenzo's oil and platelet activation in adrenomyeloneuropathy and asymptomatic X-linked adrenoleukodystrophy.

    PubMed

    Konijnenberg, A; van Geel, B M; Sturk, A; Schaap, M C; von dem Borne, A E; de Bruijne-Admiraal, L G; Schutgens, R B; Assies, J; Barth, P G

    1998-01-01

    X-linked adrenoleukodystrophy (X-ALD) is an inherited disorder of peroxisomal beta-oxidation, which results in accumulation of very long-chain fatty acids, causing damage to the nervous system, adrenal cortex and testis. The two most frequent phenotypes are childhood cerebral adrenoleukodystrophy (CCALD) and adrenomyeloneuropathy (AMN). Some affected males demonstrate no clinical signs (asymptomatic ALD), whereas female carriers can also be affected. Patients with X-ALD have been treated with Lorenzo's oil, a 4:1 combination of oleic acid and erucic acid, with thrombocytopenia as the main side effect and sometimes leading to a hemorrhagic diathesis. We studied platelet count, size and membrane surface exposure of platelet activation antigens in 17 adult X-ALD patients. Eight patients used the prescribed amount of erucic acid (as glyceroltrierucate) or more (very compliant), five used less(compliant), and four did not use the diet. All eight very compliant patients had highly enlarged platelets and seven manifested thrombocytopenia. An enhanced in vivo platelet activation status was established by increased platelet surface expression of P-selectin (CD62P, PADGEM, GMP-140) in five of the seven thrombocytopenic patients, and of increased fibrinogen receptor exposure (measured with the antibody PAC-1) in three of these five patients. The other nine compliant or untreated patients had normal platelet counts and, generally, normal P-selection and fibrinogen receptor expression. A diet-induced 7- to 27-fold enrichment of erucic acid was observed in the platelets of the four patients studied. We conclude that the thrombocytopenia in AMN patients using Lorenzo'soil is associated with circulating platelets that have an increased erucic acid content, size and activation status. We hypothesize that the erucic acid in some way induces the increased size and thus, directly or indirectly, increased platelet activation or instability in vivo. This then causes the thrombocytopenia

  19. The effect of science demonstrations as a community service activity on pre-service science teachers' teaching practices

    NASA Astrophysics Data System (ADS)

    Gurel, Derya Kaltakci

    2016-03-01

    In the scope of this study, pre-service science teachers (PSST) developed and carried out science demonstrations with everyday materials for elementary school students as a community service activity. 17 PSST enrolled in the community services practices course at Kocaeli University comprised the sample of the present study. Community service practices aim to develop consciousness of social responsibility and professional skills, as well as to gain awareness of social and community problems and find solutions for pre-service teachers. With this aim, each PSST developed five science demonstration activities and their brochures during a semester. At the end of the semester, a total of 85 demonstrations were carried out at public elementary schools, which are especially located in socioeconomically poor districts of Kocaeli, Turkey. In the present case study, the effect of developing and carrying out science demonstrations for elementary school students on six of the PSST' teaching practices on density and buoyancy concept was investigated. 30-minute interviews conducted with each PSST, videos recorded during their demonstration performances, brochures they prepared for their demonstration activities, and reflection papers were used as data collection tools of the study. The results showed that community service practices with science demonstrations had positive effects on PSST' science content knowledge and pedagogical content knowledge.

  20. Microdevelopment during an activity-based science lesson

    NASA Astrophysics Data System (ADS)

    Parziale, Jim

    1997-11-01

    The purpose of this study was to describe the microdevelopment of task-related skills during a classroom science activity. Pairs of fifth and pairs of seventh grade students were videotaped as they constructed marshmallow and toothpick bridges. A skill theory based system of analysis was developed and used to detect the construction of new understandings. Patterns of change observed in these understandings were used to infer three means of self-construction: shifts of focus, bridging mechanisms and distributed cognition. Shift of focus is a mechanism used by students to efficiently explore a web of possibilities, collect ideas and make observations for later coordination as new understandings. Bridging mechanisms are partially built conversational structures that scaffolded the construction of higher level thinking structures. Students used the distributed cognition mechanism to test the adaptiveness of their design ideas without the need to fully coordinate an understandings of these designs. An integrated model of these three mechanisms is proposed specific to this task. This model describes how these mechanisms spontaneously emerged and interacted to support the construction of mental representations.

  1. Conversations about Science across Activities in Mexican-Descent Families

    ERIC Educational Resources Information Center

    Siegel, Deborah R.; Esterly, Jennifer; Callanan, Maureen A.; Wright, Ramser; Navarro, Rocio

    2007-01-01

    Parent-child "everyday" conversations have been suggested as a source of children's early science learning. If such conversations are important, then it would be pertinent to know whether children from different family backgrounds have different experiences talking about science in informal settings. We focus on the relation between parents'…

  2. DNA Fingerprinting Using PCR: A Practical Forensic Science Activity

    ERIC Educational Resources Information Center

    Choi, Hyun-Jung; Ahn, Jung Hoon; Ko, Minsu

    2008-01-01

    This paper describes a forensic science simulation programme applicable for use in colleges. Students were asked to find a putative suspect by DNA fingerprinting using a simple protocol developed in this study. DNA samples were obtained from a hair root and a drop of blood, common sources of DNA in forensic science. The DNA fingerprinting protocol…

  3. Assessing Activity Limitations in Patients with Neuromuscular Diseases: Is the ACTIVLIM Questionnaire Linked to ICF and ICF-CY?

    ERIC Educational Resources Information Center

    Raggi, Alberto; Leonardi, Matilde

    2009-01-01

    The objective of this study was to explore to what extent the ACTIVLIM questionnaire, designed to evaluate limitations in activities involving upper and lower limbs in adults and children with neuromuscular diseases, is linked to the domains of the Activities and Participation of the International Classification of Functioning, Disability and…

  4. Links Between Watershed Activities and the Degradation of Coastal, Tidal Salt Marshes in Southern New England USA

    EPA Science Inventory

    Human activities (e.g., land development, wastewater) in coastal watersheds in New England USA are linked with community- and system-level changes in tidal, organic-rich salt marshes. Significant relationships between various indicators of watershed activities and ecosystem stru...

  5. Evidence for a link between global lightning activity and upper tropospheric water vapour

    PubMed

    Price

    2000-07-20

    Tropospheric water vapour is a key element of the Earth's climate, which has direct effects as a greenhouse gas, as well as indirect effects through interaction with clouds, aerosols and tropospheric chemistry. Small changes in upper-tropospheric water vapour have a much larger impact on the greenhouse effect than small changes in water vapour in the lower atmosphere, but whether this impact is a positive or negative feedback remains uncertain. The main challenge in addressing this question is the difficulty in monitoring upper-tropospheric water vapour globally over long timescales. Here I show that upper-tropospheric water-vapour variability and global lightning activity are closely linked, suggesting that upper-tropospheric water-vapour changes can be inferred from records of global lightning activity, readily obtained from observations at a single location on the Earth's surface. This correlation reflects the fact that continental deep-convective thunderstorms transport large amounts of water vapour into the upper troposphere and thereby dominate the variations of global upper-tropospheric water vapour while producing most of the lightning on Earth. As global lightning induces Schumann resonances, an electromagnetic phenomenon in the atmosphere that can be observed easily at low cost, monitoring of these resonances might provide a convenient method for tracking upper-tropospheric water-vapour variability and hence contribute to a better understanding of the processes affecting climate change.

  6. Links between Osteoarthritis and Diabetes:Implications for Management from a Physical Activity Perspective

    PubMed Central

    Piva, Sara R.; Susko, Allyn M.; Khoja, Samannaaz S.; Josbeno, Deborah A.; Fitzgerald, G. Kelley; Toledo, Frederico G. S.

    2014-01-01

    SYNOPSIS Osteoarthritis (OA) and type 2 diabetes mellitus (T2DM) often co-exist in older adults. There is increased susceptibility to develop arthritis in those with T2DM, which is supported by observations of higher prevalence of arthritis in those with T2DM (52%) compared to those without it (27%). The association between OA and T2DM has been traditionally attributed to underlying shared risk factors of age and obesity. Emerging evidence suggests that alterations in lipid metabolism and hyperglycemia might have a direct impact on cartilage health and subchondral bone that contribute to the development and/or progression of OA. Adequate management of older persons with both OA and T2DM benefits from a comprehensive understanding of the risk factors associated with these diseases. In this review, we discuss common risk factors and emerging underlying links between OA and T2DM, and emphasize the importance of physical activity to improve metabolism and decrease disability and pain in this population. Implications for safe and effective physical activity approaches in older patients with OA and T2DM are also discussed. PMID:25453302

  7. Catalytic activity of non-cross-linked microcrystals of aspartate aminotransferase in poly(ethylene glycol).

    PubMed Central

    Kirsten, H; Christen, P

    1983-01-01

    The molar activity of crystalline mitochondrial aspartate aminotransferase is decreased to 10% of that of the enzyme in solution. The activity was measured in suspensions of non-cross-linked microcrystals (average dimensions 22 microns X 5 microns X 0.8 microns) in 30% (w/v) poly(ethylene glycol). Kinetic tests ruled out the possibility that diffusion of the substrate in the crystals is rate-limiting. The observed decrease in catalytic efficiency can be attributed exclusively to crystal-packing effects. A direct inhibition by poly(ethylene glycol) is excluded because poly(ethylene glycol), with average Mr 6000, cannot penetrate the liquid channels of the crystals, owing to its large Stokes radius. The crystals examined were triclinic and of the same habit as those used for high-resolution X-ray-crystallographic analysis [Ford, Eichele & Jansonius (1980) Proc. Natl. Acad. Sci. U.S.A. 77, 2559-2563]. The catalytic competence of crystalline aspartate aminotransferase confirms the relevance of the spatial model of this protein for the elucidation of its mechanism of action. Images Fig. 1. PMID:6870840

  8. Bilirubin, platelet activation and heart disease: a missing link to cardiovascular protection in Gilbert's syndrome?

    PubMed

    Kundur, Avinash R; Singh, Indu; Bulmer, Andrew C

    2015-03-01

    Gilbert's syndrome (GS) is a relatively common condition, inducing a benign, non-hemolytic, unconjugated hyperbilirubinemia. Gilbert's Syndrome is associated with mutation in the Uridine Glucuronosyl Transferase 1A1 (UGT1A1) gene promoter, reducing UGT1A1 activity, which normally conjugates bilirubin allowing its elimination from the blood. Individuals with GS demonstrate mildly elevated plasma antioxidant capacity caused by elevated levels of unconjugated bilirubin (UCB), reduced thiols and glutathione. Interestingly, the development of, and risk of mortality from, cardiovascular disease is remarkably reduced in GS individuals. An explanation for this protection may be explained by bilirubin's ability to inhibit multiple processes that induce platelet hyper-reactivity and thrombosis, thus far under-appreciated in the literature. Reactive oxygen species are produced continuously via metabolic processes and have the potential to oxidatively modify proteins and lipids within cell membranes, which may encourage the development of thrombosis and CVDs. Oxidative stress induced platelet hyper-reactivity significantly increases the risk of thrombosis, which can potentially lead to tissue infarction. Here, we discuss the possible mechanisms by which increased antioxidant status might influence platelet function and link this to cardiovascular protection in GS. In summary, this is the first article to discuss the possible role of bilirubin as an anti-thrombotic agent, which inhibits platelet activation and potentially, organ infarction, which could contribute to the reduced mortality rate in mildly hyperbilirbinemic individuals. PMID:25576848

  9. 75 FR 15713 - Office of Biotechnology Activities; Office of Science Policy; Office of the Director; Notice of a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-30

    ... HUMAN SERVICES National Institutes of Health Office of Biotechnology Activities; Office of Science..., Advisory Committee Coordinator, Office of Biotechnology Activities, Office of Science Policy, Office of the... of Biotechnology Activities, National Institutes of Health. BILLING CODE 4140-01-P...

  10. 75 FR 10293 - Office of Biotechnology Activities; Office of Science Policy; Office of the Director; Notice of a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-05

    ... HUMAN SERVICES National Institutes of Health Office of Biotechnology Activities; Office of Science.... Laurie Lewallen, Advisory Committee Coordinator, Office of Biotechnology Activities, Office of Science.... Patterson, Director, Office of Biotechnology Activities, National Institutes of Health. BILLING CODE...

  11. A Framework for Linking High-Throughput Modeling and Measurement Efforts to Advance 21st Century Exposure Science

    EPA Science Inventory

    The past five years have witnessed a rapid shift in the exposure science and toxicology communities towards high-throughput (HT) analyses of chemicals as potential stressors of human and ecological health. Modeling efforts have largely led the charge in the exposure science field...

  12. An In-Class Discussion Activity on the Nature of Science and Intelligent Design

    ERIC Educational Resources Information Center

    Thomas, Brian C.

    2009-01-01

    In this paper I describe an in-class discussion activity aimed at helping elementary education majors in a physical science course think about issues surrounding the inclusion of "Intelligent Design" in public school science standards. I discuss the background instruction given, the content of the activity, and some results from its use in class.

  13. From Yeast to Hair Dryers: Effective Activities for Teaching Environmental Sciences.

    ERIC Educational Resources Information Center

    Nolan, Kathleen A.

    2001-01-01

    Reports on four experiments and/or activities that were used to stimulate student interest in environmental science. Makes the case that varying classroom activities in the environmental science classroom makes the teaching and learning experience more alive and vital to both instructor and student. (Author/MM)

  14. The Art and Science Connection: Hands-on Activities for Intermediate Students.

    ERIC Educational Resources Information Center

    Tolley, Kimberley

    Most people think that the artist and the scientist live in two totally different worlds. However, art and science are only two different ways of understanding and knowing the world. To help intermediate students make a connection between art and science, a collection of hands-on activities have been developed. By engaging in these activities that…

  15. Place-Based Science Teaching and Learning: 40 Activities for K-8 Classrooms

    ERIC Educational Resources Information Center

    Buxton, Cory A.; Provenzo, Eugene F., Jr.

    2011-01-01

    Grounded in theory and best-practices research, this practical text provides elementary and middle school teachers with 40 place-based activities that will help them to make science learning relevant to their students. This text provides teachers with both a rationale and a set of strategies and activities for teaching science in a local context…

  16. Teaching Primary Science: Emotions, Identity and the Use of Practical Activities

    ERIC Educational Resources Information Center

    Cripps Clark, John; Groves, Susie

    2012-01-01

    This paper uses cultural historical activity theory to examine the interactions between the choices primary teachers make in the use of practical activities in their teaching of science and the purposes they attribute to these; their emotions, background and beliefs; and the construction of their identities as teachers of science. It draws on four…

  17. The Structural Challenge: A Simple Design-Based Science Activity to Foster Creativity among Kinaesthetic Learners

    ERIC Educational Resources Information Center

    Amir, Nazir; Subramaniam, R.

    2014-01-01

    A suitable way for teachers to present science content and foster creativity in less academically inclined students is by getting them to engage in design-based science activities and guiding them along the way. This study illustrates how a design-and-make activity was carried out with the aim of getting students to showcase their creativity while…

  18. The Art and Science Connection. Hands-On Activities for Primary Students.

    ERIC Educational Resources Information Center

    Tolley, Kimberley

    Most people think that the artist and the scientist live in two totally different worlds. However, art and science are only two different ways of understanding and knowing the world. To help primary students make a connection between art and science, a collection of hands-on activities have been developed. By engaging in these activities that…

  19. Perspectives on the Contribution of Social Science to Adapted Physical Activity: Looking Forward, Looking Back

    ERIC Educational Resources Information Center

    Causgrove Dunn, Janice; Cairney, John; Zimmer, Chantelle

    2016-01-01

    In this article, we reflect on the contributions of the social sciences to the field of adapted physical activity by examining the theories and methods that have been adopted from the social science disciplines. To broaden our perspective on adapted physical activity and provide new avenues for theoretical and empirical exploration, we discuss and…

  20. Don't Overlook Writing as an Activity in the Elementary Science Classroom.

    ERIC Educational Resources Information Center

    Otto, Paul B.

    The legitimacy of writing as a science activity is supported in this paper and ways of incorporating it in an elementary science program are suggested. Reasons are delineated on how writing can help students improve their skills in the areas of critical thinking, problem solving, questioning, and concept clarification. Specific activities are…

  1. Basic Science Process Skills. An Inservice Workshop Kit: Outlines and Activities.

    ERIC Educational Resources Information Center

    Rowland, Paul; And Others

    A science process skill project was developed to help elementary teachers meet competency standards in New Mexico for teaching the process approach in their science classes. An outline of the process skills along with recommended activities are presented in this document. Performance objectives are identified and a sample activity form is…

  2. Students' Representations of Scientific Practice during a Science Internship: Reflections from an activity-theoretic perspective

    NASA Astrophysics Data System (ADS)

    Hsu, Pei-Ling; van Eijck, Michiel; Roth, Wolff-Michael

    2010-06-01

    Working at scientists' elbows is one suggestion that educators make to improve science education, because such "authentic experiences" provide students with various types of science knowledge. However, there is an ongoing debate in the literature about the assumption that authentic science activities can enhance students' understandings of scientific practice. The purpose of the study is to further address the debate in terms of the ethnographic data collected during an internship programme for high school students right through to their public presentations at the end. Drawing on activity theory to analyse these presentations, we found that students presented scientific practice as accomplished by individual personnel without collaboration in the laboratory. However, our ethnographic data of their internship interaction show that students have had conversations about the complex collaborations within and outside the laboratory. This phenomenon leads us to claim that students experienced authentic science in their internships, but their subsequent representations of authentic science are incomplete. That is, participating in authentic science internships and reporting scientific practice are embedded activities that constitute different goals and conditions rather than unrefracted reflections of one another. The debate on the influence on students' understanding of science practice is not simply related to situating students in authentic science contexts, but also related to students' values and ideology of reporting their understanding of and about science. To help students see these "invisible" moments of science practice is therefore crucial. We make suggestions for how the invisible in and of authentic science may be made visible.

  3. The role of children's journals in elementary school science activities

    NASA Astrophysics Data System (ADS)

    Shepardson, Daniel P.; Britsch, Susan J.

    2001-01-01

    : This article reports on a study that investigated the ways that children's use of science journals aided their acquisition of science understandings in one kindergarten and one fourth-grade classroom. The questions for investigation were: how does the child contextualize the science experience on the journal page? How do child-produced graphics on the journal page reflect the children's experiences with other school texts? The study found that children recontextualized their understandings of the science investigation and phenomena by using three types of mental contexts that were reflected in their science journals: these contexts were imaginary, experienced, and investigative worlds. By drawing on these three worlds or internal contexts, the children were able to pull the external phenomenon into an internal context that was familiar to them. The child's construction of ideas about a current science experience as expressed on the journal page may reflect experiences with other conventional texts. In this study the children's representations of their imaginary, experienced and/or investigative worlds were shaped by other texts and structures such as school science texts.

  4. Community Links

    ERIC Educational Resources Information Center

    Nelson, Mary

    1975-01-01

    At Moraine Valley Community College (Illinois), a chain of events, programs, activities, and services has linked the college and community in such areas as fine arts, ethnic groups, public services, community action, community service, and community education. (Author/NHM)

  5. The link in Linking

    PubMed Central

    Caldwell, Jane C; Chiale, Pablo A; Gonzalez, Mario D; Baranchuk, Adrian

    2013-01-01

    We present 2 cases of the slow-fast form of AVNRT with initially narrow QRS complexes followed by sudden unexpected transition to persistently wide QRS complexes due to aberrant intraventricular conduction. Introduction of a properly timed extrastimulus in one case and critical oscillations in cycle length due to short-long coupling in the second case set the stage for the initial bundle branch block. However, persistence of the aberrancy pattern once the initial event abated was maintained by the "linking" phenomenon. Delayed, retrograde concealed activation from the contralateral bundle branch perpetuated the initial bundle branch block. PMID:23840106

  6. Methods of Engaging Preschool-age Children in Science Practices During Astronomy Activities

    NASA Astrophysics Data System (ADS)

    Plummer, J. D.

    2015-11-01

    Providing preschool children with science learning experiences may improve their later science literacy. Further, research shows that children are capable of engaging in the same kinds of scientific reasoning as adults. An initial step towards increasing the opportunities for children to engage in science is to improve our understanding of how to support children's engagement in the practices of science in astronomy. To this end, the My Sky Tonight project is developing and evaluating astronomy activities for informal science educators to use with young children. I have gathered video of a series of astronomy workshops that engaged preschool-age children with My Sky Tonight-developed activities. This paper describes features of these museum-based astronomy activities that supported young children in evidence-based science practices.

  7. Climate Change Adaptation Science Activities at NASA Johnson Space Center

    NASA Technical Reports Server (NTRS)

    Stefanov, William L.; Lulla, Kamlesh

    2012-01-01

    The Johnson Space Center (JSC), located in the southeast metropolitan region of Houston, TX is the prime NASA center for human spaceflight operations and astronaut training, but it also houses the unique collection of returned extraterrestrial samples, including lunar samples from the Apollo missions. The Center's location adjacent to Clear Lake and the Clear Creek watershed, an estuary of Galveston Bay, puts it at direct annual risk from hurricanes, but also from a number of other climate-related hazards including drought, floods, sea level rise, heat waves, and high wind events all assigned Threat Levels of 2 or 3 in the most recent NASA Center Disaster/Risk Matrix produced by the Climate Adaptation Science Investigator Working Group. Based on prior CASI workshops at other NASA centers, it is recognized that JSC is highly vulnerable to climate-change related hazards and has a need for adaptation strategies. We will present an overview of prior CASI-related work at JSC, including publication of a climate change and adaptation informational data brochure, and a Resilience and Adaptation to Climate Risks Workshop that was held at JSC in early March 2012. Major outcomes of that workshop that form a basis for work going forward are 1) a realization that JSC is embedded in a regional environmental and social context, and that potential climate change effects and adaptation strategies will not, and should not, be constrained by the Center fence line; 2) a desire to coordinate data collection and adaptation planning activities with interested stakeholders to form a regional climate change adaptation center that could facilitate interaction with CASI; 3) recognition that there is a wide array of basic data (remotely sensed, in situ, GIS/mapping, and historical) available through JSC and other stakeholders, but this data is not yet centrally accessible for planning purposes.

  8. Classroom Activities: Simple Strategies to Incorporate Student-Centered Activities within Undergraduate Science Lectures

    PubMed Central

    Lom, Barbara

    2012-01-01

    The traditional science lecture, where an instructor delivers a carefully crafted monolog to a large audience of students who passively receive the information, has been a popular mode of instruction for centuries. Recent evidence on the science of teaching and learning indicates that learner-centered, active teaching strategies can be more effective learning tools than traditional lectures. Yet most colleges and universities retain lectures as their central instructional method. This article highlights several simple collaborative teaching techniques that can be readily deployed within traditional lecture frameworks to promote active learning. Specifically, this article briefly introduces the techniques of: reader’s theatre, think-pair-share, roundtable, jigsaw, in-class quizzes, and minute papers. Each technique is broadly applicable well beyond neuroscience courses and easily modifiable to serve an instructor’s specific pedagogical goals. The benefits of each technique are described along with specific examples of how each technique might be deployed within a traditional lecture to create more active learning experiences. PMID:23494568

  9. [Activities of Goddard Earth Sciences and Technology Center, Maryland University

    NASA Technical Reports Server (NTRS)

    2003-01-01

    The Goddard Space Flight Center (GSFC) is recognized as a world leader in the application of remote sensing and modeling aimed at improving knowledge of the Earth system. The Goddard Earth Sciences Directorate plays a central role in NASA's Earth Observing System and the U.S. Global Change Research Program. Goddard Earth Sciences and Technology (GEST) is organized as a cooperative agreement with the GSFC to promote excellence in the Earth sciences, and is a consortium of universities and corporations (University of Maryland Baltimore County, Howard University, Hampton University, Caelum Research Corporation and Northrop Grumman Corporation). The aim of this new program is to attract and introduce promising students in their first or second year of graduate studies to Oceanography and Earth system science career options through hands-on instrumentation research experiences on coastal processes at NASA's Wallops Flight Facility on the Eastern Shore of Virginia.

  10. Capturing citation activity in three health sciences departments: a comparison study of Scopus and Web of Science.

    PubMed

    Sarkozy, Alexandra; Slyman, Alison; Wu, Wendy

    2015-01-01

    Scopus and Web of Science are the two major citation databases that collect and disseminate bibliometric statistics about research articles, journals, institutions, and individual authors. Liaison librarians are now regularly called upon to utilize these databases to assist faculty in finding citation activity on their published works for tenure and promotion, grant applications, and more. But questions about the accuracy, scope, and coverage of these tools deserve closer scrutiny. Discrepancies in citation capture led to a systematic study on how Scopus and Web of Science compared in a real-life situation encountered by liaisons: comparing three different disciplines at a medical school and nursing program. How many articles would each database retrieve for each faculty member using the author-searching tools provided? How many cited references for each faculty member would each tool generate? Results demonstrated troubling differences in publication and citation activity capture between Scopus and Web of Science. Implications for librarians are discussed. PMID:25927511

  11. Capturing citation activity in three health sciences departments: a comparison study of Scopus and Web of Science.

    PubMed

    Sarkozy, Alexandra; Slyman, Alison; Wu, Wendy

    2015-01-01

    Scopus and Web of Science are the two major citation databases that collect and disseminate bibliometric statistics about research articles, journals, institutions, and individual authors. Liaison librarians are now regularly called upon to utilize these databases to assist faculty in finding citation activity on their published works for tenure and promotion, grant applications, and more. But questions about the accuracy, scope, and coverage of these tools deserve closer scrutiny. Discrepancies in citation capture led to a systematic study on how Scopus and Web of Science compared in a real-life situation encountered by liaisons: comparing three different disciplines at a medical school and nursing program. How many articles would each database retrieve for each faculty member using the author-searching tools provided? How many cited references for each faculty member would each tool generate? Results demonstrated troubling differences in publication and citation activity capture between Scopus and Web of Science. Implications for librarians are discussed.

  12. Cross-linked enzyme aggregates (CLEAs) of Pencilluim notatum lipase enzyme with improved activity, stability and reusability characteristics.

    PubMed

    Rehman, Saima; Bhatti, Haq Nawaz; Bilal, Muhammad; Asgher, Muhammad

    2016-10-01

    Cross-linked enzyme aggregates (CLEAs) are considered as an effective tool for the immobilization of enzyme. In this study, Pencillium notatum lipase (PNL) was immobilized as carrier free cross-linked enzyme aggregates using glutaraldehyde (GLA) and Ethylene glycol-bis [succinic acid N-hydroxysuccinimide] (EG-NHS) as cross-linking agents. The optimal conditions for the synthesis of an efficient lipase CLEAs such as precipitant type, the nature and amount of cross-linking reagent, and cross-linking time were optimized. The recovered activities of CLEAs were considerably dependent on the concentration of GLA; however, the activity recovery was not severely affected by EG-NHS as a mild cross-linker. The EG-NHS aggregates displayed superior hydrolytic (52.08±2.52%) and esterification (64.42%) activities as compared to GLA aggregates which showed 23.8±1.86 and 34.54% of hydrolytic and esterification activity, respectively. Morphological analysis by fluorescence and scanning electron microscope revealed that EG-NHS aggregates were smaller in size with larger surface area compared to GLA aggregates. The pH optima of both types of CLEAs were displaced to slightly alkaline region and higher temperature as compared to native enzyme. Highest enzyme activity of CLEAs was achieved at the pH of 9.0 and 42°C temperature. Moreover, a significant improvement in the thermal resistance was also recorded after immobilization. After ten reusability cycles in aqueous medium, GLA and EG-NHS cross-linked lipase CLEAs preserved 63.62% and 70.9% of their original activities, respectively. The results suggest that this novel CLEA-lipase is potentially usable in many industrial applications.

  13. Cross-linked enzyme aggregates (CLEAs) of Pencilluim notatum lipase enzyme with improved activity, stability and reusability characteristics.

    PubMed

    Rehman, Saima; Bhatti, Haq Nawaz; Bilal, Muhammad; Asgher, Muhammad

    2016-10-01

    Cross-linked enzyme aggregates (CLEAs) are considered as an effective tool for the immobilization of enzyme. In this study, Pencillium notatum lipase (PNL) was immobilized as carrier free cross-linked enzyme aggregates using glutaraldehyde (GLA) and Ethylene glycol-bis [succinic acid N-hydroxysuccinimide] (EG-NHS) as cross-linking agents. The optimal conditions for the synthesis of an efficient lipase CLEAs such as precipitant type, the nature and amount of cross-linking reagent, and cross-linking time were optimized. The recovered activities of CLEAs were considerably dependent on the concentration of GLA; however, the activity recovery was not severely affected by EG-NHS as a mild cross-linker. The EG-NHS aggregates displayed superior hydrolytic (52.08±2.52%) and esterification (64.42%) activities as compared to GLA aggregates which showed 23.8±1.86 and 34.54% of hydrolytic and esterification activity, respectively. Morphological analysis by fluorescence and scanning electron microscope revealed that EG-NHS aggregates were smaller in size with larger surface area compared to GLA aggregates. The pH optima of both types of CLEAs were displaced to slightly alkaline region and higher temperature as compared to native enzyme. Highest enzyme activity of CLEAs was achieved at the pH of 9.0 and 42°C temperature. Moreover, a significant improvement in the thermal resistance was also recorded after immobilization. After ten reusability cycles in aqueous medium, GLA and EG-NHS cross-linked lipase CLEAs preserved 63.62% and 70.9% of their original activities, respectively. The results suggest that this novel CLEA-lipase is potentially usable in many industrial applications. PMID:27365121

  14. Linking Student Achievement and Teacher Science Content Knowledge about Climate Change: Ensuring the Nations 3 Million Teachers Understand the Science through an Electronic Professional Development System

    NASA Astrophysics Data System (ADS)

    Niepold, F.; Byers, A.

    2009-12-01

    The scientific complexities of global climate change, with wide-ranging economic and social significance, create an intellectual challenge that mandates greater public understanding of climate change research and the concurrent ability to make informed decisions. The critical need for an engaged, science literate public has been repeatedly emphasized by multi-disciplinary entities like the Intergovernmental Panel on Climate Change (IPCC), the National Academies (Rising Above the Gathering Storm report), and the interagency group responsible for the recently updated Climate Literacy: The Essential Principles of Climate Science. There is a clear need for an American public that is climate literate and for K-12 teachers confident in teaching relevant science content. A key goal in the creation of a climate literate society is to enhance teachers’ knowledge of global climate change through a national, scalable, and sustainable professional development system, using compelling climate science data and resources to stimulate inquiry-based student interest in science, technology, engineering, and mathematics (STEM). This session will explore innovative e-learning technologies to address the limitations of one-time, face-to-face workshops, thereby adding significant sustainability and scalability. The resources developed will help teachers sift through the vast volume of global climate change information and provide research-based, high-quality science content and pedagogical information to help teachers effectively teach their students about the complex issues surrounding global climate change. The Learning Center is NSTA's e-professional development portal to help the nations teachers and informal educators learn about the scientific complexities of global climate change through research-based techniques and is proven to significantly improve teacher science content knowledge.

  15. Perezhivanie and classroom discourse: a cultural-historical perspective on "Discourse of design based science classroom activities"

    NASA Astrophysics Data System (ADS)

    Adams, Megan; March, Sue

    2015-06-01

    Flavio Azevedo, Peggy Martalock and Tugba Keser challenge the `argumentation focus of science lessons' and propose that through a `design-based approach' emergent conversations with the teacher offer possibilities for different types of discussions to enhance pedagogical discourse in science classrooms. This important paper offers a "preliminary contribution to a general theory" regarding the link between activity types and discourse practices. Azevedo, Martalock and Keser offer a general perspective with a sociocultural framing for analysis of classroom discourse. Interestingly the specific concepts drawn upon are from conversation analysis; there are few sociocultural concepts explored in detail. Therefore, in this article we focus on a cultural historical (Vygotsky in The collected works of L. S. Vygotsky. The history and development of higher mental functions, vol 4. Plenum Press, New York, 1987; The Vygotsky reader. Black, Cambridge, 1994) methodology to explore, analyse and explain how we would use a different theoretical lens. We argue that a cultural historical reading of argumentation in science lessons and design based activity will expand Azevedo, Martalock and Keser's proposed general theory of activity types and discourse practices. Specifically, we use Lev Vygotksy's idea of perezhivanie as the unit of analysis to reconceptualise this important paper. We focus on the holistic category of students' emotional experience through discourse while developing scientific awareness.

  16. Linking rapid erosion of the Mekong River delta to human activities.

    PubMed

    Anthony, Edward J; Brunier, Guillaume; Besset, Manon; Goichot, Marc; Dussouillez, Philippe; Nguyen, Van Lap

    2015-01-01

    As international concern for the survival of deltas grows, the Mekong River delta, the world's third largest delta, densely populated, considered as Southeast Asia's most important food basket, and rich in biodiversity at the world scale, is also increasingly affected by human activities and exposed to subsidence and coastal erosion. Several dams have been constructed upstream of the delta and many more are now planned. We quantify from high-resolution SPOT 5 satellite images large-scale shoreline erosion and land loss between 2003 and 2012 that now affect over 50% of the once strongly advancing >600 km-long delta shoreline. Erosion, with no identified change in the river's discharge and in wave and wind conditions over this recent period, is consistent with: (1) a reported significant decrease in coastal surface suspended sediment from the Mekong that may be linked to dam retention of its sediment, (2) large-scale commercial sand mining in the river and delta channels, and (3) subsidence due to groundwater extraction. Shoreline erosion is already responsible for displacement of coastal populations. It is an additional hazard to the integrity of this Asian mega delta now considered particularly vulnerable to accelerated subsidence and sea-level rise, and will be exacerbated by future hydropower dams. PMID:26446752

  17. Linking rapid erosion of the Mekong River delta to human activities

    NASA Astrophysics Data System (ADS)

    Anthony, Edward J.; Brunier, Guillaume; Besset, Manon; Goichot, Marc; Dussouillez, Philippe; Nguyen, Van Lap

    2015-10-01

    As international concern for the survival of deltas grows, the Mekong River delta, the world’s third largest delta, densely populated, considered as Southeast Asia’s most important food basket, and rich in biodiversity at the world scale, is also increasingly affected by human activities and exposed to subsidence and coastal erosion. Several dams have been constructed upstream of the delta and many more are now planned. We quantify from high-resolution SPOT 5 satellite images large-scale shoreline erosion and land loss between 2003 and 2012 that now affect over 50% of the once strongly advancing >600 km-long delta shoreline. Erosion, with no identified change in the river’s discharge and in wave and wind conditions over this recent period, is consistent with: (1) a reported significant decrease in coastal surface suspended sediment from the Mekong that may be linked to dam retention of its sediment, (2) large-scale commercial sand mining in the river and delta channels, and (3) subsidence due to groundwater extraction. Shoreline erosion is already responsible for displacement of coastal populations. It is an additional hazard to the integrity of this Asian mega delta now considered particularly vulnerable to accelerated subsidence and sea-level rise, and will be exacerbated by future hydropower dams.

  18. Linking rapid erosion of the Mekong River delta to human activities.

    PubMed

    Anthony, Edward J; Brunier, Guillaume; Besset, Manon; Goichot, Marc; Dussouillez, Philippe; Nguyen, Van Lap

    2015-10-08

    As international concern for the survival of deltas grows, the Mekong River delta, the world's third largest delta, densely populated, considered as Southeast Asia's most important food basket, and rich in biodiversity at the world scale, is also increasingly affected by human activities and exposed to subsidence and coastal erosion. Several dams have been constructed upstream of the delta and many more are now planned. We quantify from high-resolution SPOT 5 satellite images large-scale shoreline erosion and land loss between 2003 and 2012 that now affect over 50% of the once strongly advancing >600 km-long delta shoreline. Erosion, with no identified change in the river's discharge and in wave and wind conditions over this recent period, is consistent with: (1) a reported significant decrease in coastal surface suspended sediment from the Mekong that may be linked to dam retention of its sediment, (2) large-scale commercial sand mining in the river and delta channels, and (3) subsidence due to groundwater extraction. Shoreline erosion is already responsible for displacement of coastal populations. It is an additional hazard to the integrity of this Asian mega delta now considered particularly vulnerable to accelerated subsidence and sea-level rise, and will be exacerbated by future hydropower dams.

  19. Linking rapid erosion of the Mekong River delta to human activities

    PubMed Central

    Anthony, Edward J.; Brunier, Guillaume; Besset, Manon; Goichot, Marc; Dussouillez, Philippe; Nguyen, Van Lap

    2015-01-01

    As international concern for the survival of deltas grows, the Mekong River delta, the world’s third largest delta, densely populated, considered as Southeast Asia’s most important food basket, and rich in biodiversity at the world scale, is also increasingly affected by human activities and exposed to subsidence and coastal erosion. Several dams have been constructed upstream of the delta and many more are now planned. We quantify from high-resolution SPOT 5 satellite images large-scale shoreline erosion and land loss between 2003 and 2012 that now affect over 50% of the once strongly advancing >600 km-long delta shoreline. Erosion, with no identified change in the river’s discharge and in wave and wind conditions over this recent period, is consistent with: (1) a reported significant decrease in coastal surface suspended sediment from the Mekong that may be linked to dam retention of its sediment, (2) large-scale commercial sand mining in the river and delta channels, and (3) subsidence due to groundwater extraction. Shoreline erosion is already responsible for displacement of coastal populations. It is an additional hazard to the integrity of this Asian mega delta now considered particularly vulnerable to accelerated subsidence and sea-level rise, and will be exacerbated by future hydropower dams. PMID:26446752

  20. Severity of symptom flare after moderate exercise is linked to cytokine activity in chronic fatigue syndrome.

    PubMed

    White, Andrea T; Light, Alan R; Hughen, Ronald W; Bateman, Lucinda; Martins, Thomas B; Hill, Harry R; Light, Kathleen C

    2010-07-01

    Chronic fatigue syndrome (CFS) patients often report symptom flare (SF) for >24 h after moderate exercise (post-ex). We hypothesized that SF is linked to increases in circulating cytokines and CD40 Ligand (CD40L). In 19 CFS patients and 17 controls, mental and physical fatigue and pain symptom ratings were obtained together with serum for 11 cytokines and CD40L before and at 0.5, 8, 24, and 48 h post-ex. Before exercise, CFS had lower CD40L (p<.05) but similar cytokines versus controls. In subgroups based on SF at 48 h, high SF patients (n=11) increased in IL-1beta, IL-12, IL-6, IL-8, IL-10, and IL-13 (p<.05) 8 h post-ex. Low SF patients (n=8) showed post-ex decreases in IL-10, IL-13, and CD40L, and controls decreased in IL-10, CD40L, and TNFalpha (p<.05). Thus, in CFS, cytokine activity may vary directly with SF, which may explain prior inconsistent findings.

  1. A Professional Learning Community Activity for Science Teachers: How to Incorporate Discourse-Rich Instructional Strategies into Science Lessons

    ERIC Educational Resources Information Center

    Lewis, Elizabeth; Baker, Dale; Watts, Nievita Bueno; Lang, Michael

    2014-01-01

    In this article we describe current educational research underlying a comprehensive model for building a scientific classroom discourse community. We offer a professional development activity for a school-based professional learning community, providing specific science instructional strategies within this interactive teaching model. This design…

  2. Determining the Factors That Affect the Objectives of Pre-Service Science Teachers to Perform Outdoor Science Activities

    ERIC Educational Resources Information Center

    Karademir, Ersin; Erten, Sinan

    2013-01-01

    The purpose of this study is to determine whether pre-service teachers have an aim to perform outdoor education activities within the scope of science and technology course; by which factors this aim is affected, through The Theory of Planned Behaviour and the opinions of pre-service teachers. Accordingly, the study was designed as mixed research…

  3. Enhancing Science Education through Extracurricular Activities: A Retrospective Study of "Suzy Science and the Whiz Kids[C]"

    ERIC Educational Resources Information Center

    Kralina, Linda M.

    2009-01-01

    Extracurricular activities (ECA) are informal settings offering free-choice experiences that are generally voluntary, open-ended, non-sequential, self-directed, hands-on, and evaluation-free. This mixed methods study investigates participation in a high school science ECA by collecting the memories of former student members for their perceptions…

  4. Accommodation of GDP-Linked Sugars in the Active Site of GDP-Perosamine Synthase

    SciTech Connect

    Cook, Paul D.; Carney, Amanda E.; Holden, Hazel M.

    2009-01-12

    Perosamine (4-amino-4,6-dideoxy-d-mannose), or its N-acetylated form, is one of several dideoxy sugars found in the O-antigens of such infamous Gram-negative bacteria as Vibrio cholerae O1 and Escherichia coli O157:H7. It is added to the bacterial O-antigen via a nucleotide-linked version, namely GDP-perosamine. Three enzymes are required for the biosynthesis of GDP-perosamine starting from mannose 1-phosphate. The focus of this investigation is GDP-perosamine synthase from Caulobacter crescentus, which catalyzes the final step in GDP-perosamine synthesis, the conversion of GDP-4-keto-6-deoxymannose to GDP-perosamine. The enzyme is PLP-dependent and belongs to the aspartate aminotransferase superfamily. It contains the typically conserved active site lysine residue, which forms a Schiff base with the PLP cofactor. Two crystal structures were determined for this investigation: a site-directed mutant protein (K186A) complexed with GDP-perosamine and the wild-type enzyme complexed with an unnatural ligand, GDP-3-deoxyperosamine. These structures, determined to 1.6 and 1.7 {angstrom} resolution, respectively, revealed the manner in which products, and presumably substrates, are accommodated within the active site pocket of GDP-perosamine synthase. Additional kinetic analyses using both the natural and unnatural substrates revealed that the K{sub m} for the unnatural substrate was unperturbed relative to that of the natural substrate, but the k{sub cat} was lowered by a factor of approximately 200. Taken together, these studies shed light on why GDP-perosamine synthase functions as an aminotransferase whereas another very similar PLP-dependent enzyme, GDP-4-keto-6-deoxy-d-mannose 3-dehydratase or ColD, catalyzes a dehydration reaction using the same substrate.

  5. A PHYSICAL LINK BETWEEN JET FORMATION AND HOT PLASMA IN ACTIVE GALACTIC NUCLEI

    SciTech Connect

    Wu Qingwen; Wang Dingxiong; Cao Xinwu; Ho, Luis C. E-mail: dxwang@hust.edu.cn E-mail: lho@obs.carnegiescience.edu

    2013-06-10

    Recent observations suggest that in black hole X-ray binaries jet/outflow formation is related to the hot plasma in the vicinity of the black hole, either in the form of an advection-dominated accretion flow at low accretion rates or in a disk corona at high accretion rates. We test the viability of this scenario for supermassive black holes using two samples of active galactic nuclei distinguished by the presence (radio-strong) and absence (radio-weak) of well-collimated, relativistic jets. Each is centered on a narrow range of black hole mass but spans a very broad range of Eddington ratios, effectively simulating in a statistical manner the behavior of a single black hole evolving across a wide spread in accretion states. Unlike the relationship between the radio and optical luminosity, which shows an abrupt break between high- and low-luminosity sources at an Eddington ratio of {approx}1%, the radio emission-a measure of the jet power-varies continuously with the hard X-ray (2-10 keV) luminosity, roughly as L{sub R} {proportional_to} L{sub X}{sup 0.6-0.75}. This relation, which holds for both radio-weak and radio-strong active galaxies, is similar to the one seen in X-ray binaries. Jet/outflow formation appears to be closely linked to the conditions that give rise to the hot, optically thin coronal emission associated with accretion flows, both in the regime of low and high accretion rates.

  6. Assessing activity limitations in patients with neuromuscular diseases: is the ACTIVLIM questionnaire linked to ICF and ICF-CY?

    PubMed

    Raggi, Alberto; Leonardi, Matilde

    2009-06-01

    The objective of this study was to explore to what extent the ACTIVLIM questionnaire, designed to evaluate limitations in activities involving upper and lower limbs in adults and children with neuromuscular diseases, is linked to the domains of the Activities and Participation of the International Classification of Functioning, Disability and Health (ICF), and to its Children and Youth version (ICF-CY). Standardized ICF linking rules were applied. Items were linked to the most specific ICF-CY codes (e.g. d4501 - Walking long distances), and rolling-up procedures were applied to report information to more generic and informative upper-level codes (e.g. d450 - Walking). ACTIVLIM items were linked to 13 second-level ICF codes of Mobility, Self-care, and Domestic life chapters. The majority of ACTIVLIM items are liked to d510 - Washing oneself, d445 - Hand and arm use, and d410 - Changing basic body position. None of the ACTIVLIM items links to the codes added by the new ICF-CY classification. Disability is a multidimensional phenomenon, and measurements of disability should reflect this multidimensionality. The good psychometric properties of ACTIVLIM are demonstrated, and the aim of this mapping exercise is to provide information on its content. A relevant part of ACTIVLIM items is linked to a few ICF codes, referred to as basic body movements and washing, and other activities are less represented. We think that the ACTIVLIM covers a circumscribed set of activities and, therefore, we suggest using it together with other functional evaluation tools, to complement the range of information on activity limitations that are not covered by its items.

  7. CYLD, a deubiquitinase specific for lysine63-linked polyubiquitins, accumulates at the postsynaptic density in an activity-dependent manner

    SciTech Connect

    Dosemeci, Ayse; Thein, Soe; Yang, Yijung; Reese, Thomas S.; Tao-Cheng, Jung-Hwa

    2013-01-04

    Highlights: Black-Right-Pointing-Pointer CYLD is a deubiquitinase specific for lysine63-linked polyubiquitins. Black-Right-Pointing-Pointer Presence of CYLD in PSDs is established by biochemistry and immunoEM. Black-Right-Pointing-Pointer CYLD accumulates on PSDs upon depolarization of neurons. Black-Right-Pointing-Pointer Accumulation of CYLD at PSDs may regulate trafficking/degradation of synaptic proteins. -- Abstract: Polyubiquitin chains on proteins flag them for distinct fates depending on the type of polyubiquitin linkage. While lysine48-linked polyubiquitination directs proteins to proteasomal degradation, lysine63-linked polyubiquitination promotes different protein trafficking and is involved in autophagy. Here we show that postsynaptic density (PSD) fractions from adult rat brain contain deubiquitinase activity that targets both lysine48 and lysine63-linked polyubiquitins. Comparison of PSD fractions with parent subcellular fractions by Western immunoblotting reveals that CYLD, a deubiquitinase specific for lysine63-linked polyubiquitins, is highly enriched in the PSD fraction. Electron microscopic examination of hippocampal neurons in culture under basal conditions shows immunogold label for CYLD at the PSD complex in approximately one in four synapses. Following depolarization by exposure to high K+, the proportion of CYLD-labeled PSDs as well as the labeling intensity of CYLD at the PSD increased by more than eighty percent, indicating that neuronal activity promotes accumulation of CYLD at the PSD. An increase in postsynaptic CYLD following activity would promote removal of lysine63-polyubiquitins from PSD proteins and thus could regulate their trafficking and prevent their autophagic degradation.

  8. Completing the link between exposure science and toxicology for improved environmental health decision making: The aggregate exposure pathway framework

    DOE PAGES

    Teeguarden, Justin G.; Tan, Yu -Mei; Edwards, Stephen W.; Leonard, Jeremy A.; Anderson, Kim A.; Corley, Richard A.; Kile, Molly L.; Simonich, Staci M.; Stone, David; Tanguay, Robert L.; et al

    2016-01-13

    Here, driven by major scientific advances in analytical methods, biomonitoring, computation, and a newly articulated vision for a greater impact in public health, the field of exposure science is undergoing a rapid transition from a field of observation to a field of prediction. Deployment of an organizational and predictive framework for exposure science analogous to the “systems approaches” used in the biological sciences is a necessary step in this evolution. Here we propose the aggregate exposure pathway (AEP) concept as the natural and complementary companion in the exposure sciences to the adverse outcome pathway (AOP) concept in the toxicological sciences.more » Aggregate exposure pathways offer an intuitive framework to organize exposure data within individual units of prediction common to the field, setting the stage for exposure forecasting. Looking farther ahead, we envision direct linkages between aggregate exposure pathways and adverse outcome pathways, completing the source to outcome continuum for more meaningful integration of exposure assessment and hazard identification. Together, the two frameworks form and inform a decision-making framework with the flexibility for risk-based, hazard-based, or exposure-based decision making.« less

  9. Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework

    PubMed Central

    Teeguarden, Justin. G.; Tan, Yu-Mei; Edwards, Stephen W.; Leonard, Jeremy A.; Anderson, Kim A.; Corley, Richard A.; Harding, Anna K; Kile, Molly L.; Simonich, Staci M; Stone, David; Tanguay, Robert L.; Waters, Katrina M.; Harper, Stacey L.; Williams, David E.

    2016-01-01

    Synopsis Driven by major scientific advances in analytical methods, biomonitoring, computational tools, and a newly articulated vision for a greater impact in public health, the field of exposure science is undergoing a rapid transition from a field of observation to a field of prediction. Deployment of an organizational and predictive framework for exposure science analogous to the “systems approaches” used in the biological sciences is a necessary step in this evolution. Here we propose the Aggregate Exposure Pathway (AEP) concept as the natural and complementary companion in the exposure sciences to the Adverse Outcome Pathway (AOP) concept in the toxicological sciences. Aggregate exposure pathways offer an intuitive framework to organize exposure data within individual units of prediction common to the field, setting the stage for exposure forecasting. Looking farther ahead, we envision direct linkages between aggregate exposure pathways and adverse outcome pathways, completing the source to outcome continuum for more efficient integration of exposure assessment and hazard identification. Together, the two pathways form and inform a decision-making framework with the flexibility for risk-based, hazard-based, or exposure-based decision making. PMID:26759916

  10. Linking Europa’s Plume Activity to Tides, Tectonics, and Liquid Water

    NASA Astrophysics Data System (ADS)

    Rhoden, Alyssa R.; Hurford, Terry; Roth, Lorenz; Retherford, Kurt

    2014-11-01

    Much of the geologic activity preserved on Europa’s icy surface has been attributed to tidal deformation, mainly due to Europa’s eccentric orbit. Although the surface is geologically young, evidence of ongoing tidally-driven processes has been lacking. However, a recent observation of water vapor near Europa’s south pole suggests that it may be geologically active. Non-detections in previous and follow-up observations indicate a temporal variation in plume visibility and suggests a relationship to Europa’s tidal cycle. Similarly, the Cassini spacecraft has observed plumes emanating from the south pole of Saturn’s moon, Enceladus, and variability in the intensity of eruptions has been linked to its tidal cycle. The inference that a similar mechanism controls plumes at both Europa and Enceladus motivates further analysis of Europa’s plume behavior and the relationship between plumes, tides, and liquid water on these two satellites.We determine the locations and orientations of hypothetical tidally-driven fractures that best match the temporal variability of the plumes observed at Europa. Specifically, we identify model faults that are in tension at the time in Europa’s orbit when a plume was detected and in compression at times when the plume was not detected. We find that tidal stress driven solely by eccentricity is incompatible with the observations unless additional mechanisms are controlling the eruption timing or restricting the longevity of the plumes. In contrast, the addition of obliquity tides, and corresponding precession of the spin pole, can generate a number of model faults that are consistent with the pattern of plume detections. The locations and orientations of the model faults are robust across a broad range of precession rates and spin pole directions. Analysis of the stress variations across model faults suggests that the plumes would be best observed earlier in Europa’s orbit. Our results indicate that Europa’s plumes, if

  11. F{sub o}F{sub 1}-ATPase activity regulated by external links on {beta} subunits

    SciTech Connect

    Cheng, Jie; Zhang, Xiao-ai; Shu, Yao-Gen; Yue, Jia-Chang

    2010-01-01

    F{sub o}F{sub 1}-ATPase activity is regulated by external links on {beta} subunits with different molecular weight. It is inhibited when anti-{beta} subunit antibody, streptavidin and H9 antibody link on the {beta} subunits successively, but is activated when virus was binded. Western blotting indicated that the employed anti-{beta} antibody target was on the non-catalytic site of the {beta} subunit. Furthermore, an ESR study of spin-labeled ATP (SL-ATP) showed that the affinity of ATP to the holoenzyme increases with increasing external links on the {beta} subunits. This simple regulation method may have great potential in the design of rapid, free labeled, sensitive and selective biosensors.

  12. Life Science Start-up Activities at the Universities of Applied Sciences (UAS).

    PubMed

    Huber, Gerda

    2014-12-01

    The universities of applied sciences (UAS) provide several values for the society and economy of a country. Besides education of high level professionals, transfer of knowledge from research to applications in industry or as new start-up companies is an important task. This is done in different ways in the various disciplines. In Life Sciences, a key industry branch in Switzerland, innovation is a competitive success factor and research findings from UAS/Life Sciences contribute to the valorization of new technologies to products, services and to business performance. In order to foster awareness for the innovation need of industry, UAS install processes and support for transfer of research and technology results to marketable applications. Furthermore they may facilitate contacts of researchers and students with entrepreneurs in order to animate start-up founding as a true alternative to being employed. Access to coaching and entrepreneurial training completes the essential basis. PMID:26508606

  13. Linking inter-individual differences in the conflict adaptation effect to spontaneous brain activity.

    PubMed

    Wang, Ting; Chen, Zhencai; Zhao, Guang; Hitchman, Glenn; Liu, Congcong; Zhao, Xiaoyue; Liu, Yijun; Chen, Antao

    2014-04-15

    Conflict adaptation has been widely researched in normal and clinical populations. There are large individual differences in conflict adaptation, and it has been linked to the schizotypal trait. However, no study to date has examined how individual differences in spontaneous brain activity are related to behavioral conflict adaptation (performance). Resting-state functional magnetic resonance imaging (RS-fMRI) is a promising tool to investigate this issue. The present study evaluated the regional homogeneity (ReHo) of RS-fMRI signals in order to explore the neural basis of individual differences in conflict adaptation across two independent samples comprising a total of 67 normal subjects. A partial correlation analysis was carried out to examine the relationship between ReHo and behavioral conflict adaptation, while controlling for reaction time, standard deviation and flanker interference effects. This analysis was conducted on 39 subjects' data (sample 1); the results showed significant positive correlations in the left dorsolateral prefrontal cortex (DLPFC) and left ventrolateral prefrontal cortex. We then conducted a test-validation procedure on the remaining 28 subjects' data (sample 2) to examine the reliability of the results. Regions of interest were defined based on the correlation results. Regression analysis showed that variability in ReHo values in the DLPFC accounted for 48% of the individual differences in the conflict adaptation effect in sample 2. The present findings provide further support for the importance of the DLPFC in the conflict adaptation process. More importantly, we demonstrated that ReHo of RS-fMRI signals in the DLPFC can predict behavioral performance in conflict adaptation, which provides potential biomarkers for the early detection of cognitive control deterioration.

  14. Linking Microbial Activity with Arsenic Fate during Cow Dung Disposal of Arsenic-Bearing Wastes

    NASA Astrophysics Data System (ADS)

    Clancy, T. M.; Reddy, R.; Tan, J.; Hayes, K. F.; Raskin, L.

    2014-12-01

    To address widespread arsenic contamination of drinking water sources numerous technologies have been developed to remove arsenic. All technologies result in the production of an arsenic-bearing waste that must be evaluated and disposed in a manner to limit the potential for environmental release and human exposure. One disposal option that is commonly recommended for areas without access to landfills is the mixing of arsenic-bearing wastes with cow dung. These recommendations are made based on the ability of microorganisms to create volatile arsenic species (including mono-, di-, and tri-methylarsine gases) to be diluted in the atmosphere. However, most studies of environmental microbial communities have found only a small fraction (<0.1 %) of the total arsenic present in soils or rice paddies is released via volatilization. Additionally, past studies often have not monitored arsenic release in the aqueous phase. Two main pathways for microbial arsenic volatilization are known and include methylation of arsenic during methanogenesis and methylation by arsenite S-adenosylmethionine methyltransferase. In this study, we compare the roles of these two pathways in arsenic volatilization and aqueous mobilization through mesocosm experiments with cow dung and arsenic-bearing wastes produced during drinking water treatment in West Bengal, India. Arsenic in gaseous, aqueous, and solid phases was measured. Consistent with previous reports, less than 0.02% of the total arsenic present was volatilized. A much higher amount (~5%) of the total arsenic was mobilized into the liquid phase. Through the application of molecular tools, including 16S rRNA sequencing and quantification of gene transcripts involved in methanogenesis, this study links microbial community activity with arsenic fate in potential disposal environments. These results illustrate that disposal of arsenic-bearing wastes by mixing with cow dung does not achieve its end goal of promoting arsenic volatilization

  15. The LINK-A lncRNA Activates Normoxic HIF1α Signaling in Triple-negative Breast Cancer

    PubMed Central

    Lin, Aifu; Li, Chunlai; Xing, Zhen; Hu, Qingsong; Liang, Ke; Han, Leng; Wang, Cheng; Hawke, David H.; Wang, Shouyu; Zhang, Yanyan; Wei, Yongkun; Ma, Guolin; Park, Peter K.; Zhou, Jianwei; Zhou, Yan; Hu, Zhibin; Zhou, Yubin; Marks, Jeffery R.; Liang, Han; Hung, Mien-Chie; Lin, Chunru; Yang, Liuqing

    2016-01-01

    Although long noncoding RNAs (lncRNAs) predominately reside in nuclear and exert their functions in many biological processes, their potential involvement in cytoplasmic signal transduction remains unexplored. Here, we identified a cytoplasmic lncRNA, Long-Intergenic Noncoding RNA for Kinase Activation (LINK-A), which mediates HB-EGF triggered, EGFR:GPNMB heterodimer-dependent HIF1α phosphorylation at Tyr565 and Ser797 by BRK and LRRK2 respectively. These events cause HIF1α stabilization, HIF1α-p300 interaction, and activation of HIF1α transcriptional programs under normoxic conditions. Mechanistically, LINK-A facilitates the recruitment of BRK to EGFR:GPNMB complex and BRK kinase activation. The BRK-dependent HIF1α Tyr565 phosphorylation interferes with Pro564 hydroxylation, leading to normoxic HIF1α stabilization. Both LINK-A and LINK-A-dependent signaling pathway activation correlate with TNBC, promoting breast cancer glycolysis reprogramming and tumorigenesis. Our findings illustrate the magnitude and diversity of cytoplasmic lncRNAs in signal transduction and highlight the important roles of lncRNAs in cancer. PMID:26751287

  16. Linking Exposure Science to Current and Future Pesticide Risk Assessment: From Biomonitoring to PBPK Modeling to High Throughput Screens

    EPA Science Inventory

    Organophosphate (OP) and pyrethroid (PYR) pesticides are amongst the most widely used insecticides. While useful in their ability to control and remove insects from cattle, crops, and homes, they are inherently linked to varying degrees of toxicity as a result of their actions on...

  17. Linking the microscopic view of chemistry to real-life experiences: Intertextuality in a high-school science classroom

    NASA Astrophysics Data System (ADS)

    Wu, Hsin-Kai

    2003-11-01

    Chemistry learning involves establishing conceptual relationships among macroscopic, microscopic, and symbolic representations. Employing the notion of intertextuality to conceptualize these relationships, this study investigates how class members interactionally construct meanings of chemical representations by connecting them to real-life experiences and how the teachers' content knowledge shapes their ways to coconstruct intertextual links with students. Multiple sources of data were collected over 7 weeks with a participation of 25 eleventh graders, an experienced teacher, and a student teacher. An examination of classroom discourse shows that the intertextual links between the microscopic view of chemistry and students' real-life experiences could be initiated by students and instigated by the teachers. The teachers applied several discursive strategies to scaffold students building meaningful links based on their prior knowledge and experiences. Additionally, the experienced teacher with stronger content knowledge tended to present links in both dialogic and monologic discourses. Yet, the relatively limited content knowledge did not necessarily constrain the student teacher's interactions with students. The findings of this study provide a backdrop for further research to explore how chemistry is learned and taught in a class through the social constructivist lens.

  18. Converging genetic and functional brain imaging evidence links neuronal excitability to working memory, psychiatric disease, and brain activity

    PubMed Central

    Heck, A.; Fastenrath, M.; Ackermann, S.; Auschra, B.; Bickel, H.; Coynel, D.; Gschwind, L.; Jessen, F.; Kaduszkiewicz, H.; Maier, W.; Milnik, A.; Pentzek, M.; Riedel-Heller, S.G.; Ripke, S.; Spalek, K.; Sullivan, P.; Vogler, C.; Wagner, M.; Weyerer, S.; Wolfsgruber, S.; de Quervain, D.; Papassotiropoulos, A.

    2014-01-01

    Summary Working memory, the capacity of actively maintaining task-relevant information during a cognitive task, is a heritable trait. Working memory deficits are characteristic for many psychiatric disorders. We performed genome-wide gene-set enrichment analyses in multiple independent data sets of young and aged cognitively healthy subjects (n = 2’824), and in a large schizophrenia case-control sample (n = 32’143). The voltage-gated cation channel activity gene-set, consisting of genes related to neuronal excitability, was robustly linked to performance in working memory-related tasks across ages, and to schizophrenia. Functional brain imaging in 707 healthy participants linked this gene-set also to working memory-related activity in the parietal cortex and the cerebellum. Gene-set analyses may help to dissect the molecular underpinnings of cognitive dimensions, brain activity and psychopathology. PMID:24529980

  19. Exploring Pulses through Math, Science, and Nutrition Activities

    ERIC Educational Resources Information Center

    Smith, Diane K.; Mandal, Bidisha; Wallace, Michael L.; Riddle, Lee Anne; Kerr, Susan; Atterberry, Kelly Ann; Miles, Carol

    2016-01-01

    Purpose/Objectives: The Healthy, Hunger-Free Kids Act of 2010 includes pulses as a required component of the school lunch menu standard. Pulses are nutritionally important staple food crops, and include dry beans, dry peas, garbanzo beans, and lentils. This current study examined the short-term effectiveness of a Science, Technology, Engineering,…

  20. Science Study Aids 7: Fermentation - Activities of a Fabulous Fungus.

    ERIC Educational Resources Information Center

    McConnell, Bill

    This publication is the seventh of a series of seven supplementary investigative materials for use in secondary science classes providing up-to-date research-related investigations. This unit is structured for grades 7 through 10. It is concerned with the roles of fermentation processes in the agriculture and food industry. The guide enables…

  1. Agricultural Science Fairs: Are Students Truly Learning from This Activity?

    ERIC Educational Resources Information Center

    Boleman, C. T.; Burrell, F., Jr.

    2003-01-01

    A pretest/posttest administered to 480 fourth-graders revealed an increase in correct responses for 9 of 10 questions following participation in an agricultural science fair. Significant increases were related to knowledge of how agriculture affects everyday life. A teacher survey (n=89) indicated that it was a positive learning experience but…

  2. Medical operations and life sciences activities on space station

    NASA Technical Reports Server (NTRS)

    Johnson, P. C. (Editor); Mason, J. A. (Editor)

    1982-01-01

    Space station health maintenance facilities, habitability, personnel, and research in the medical sciences and in biology are discussed. It is assumed that the space station structure will consist of several modules, each being consistent with Orbiter payload bay limits in size, weight, and center of gravity.

  3. Activity and Action: Bridging Environmental Sciences and Environmental Education

    ERIC Educational Resources Information Center

    Tal, Tali; Abramovitch, Anat

    2013-01-01

    The main goal of this study was to examine the Environmental Workshop unit taught to Environmental Sciences majors in the high schools in Israel and learn if, and in what ways, this unit could become a model for environmental education throughout the high school curriculum. We studied the special characteristics of the Environmental Workshop (EW)…

  4. The Inventive Mind in Science: Creative Thinking Activities.

    ERIC Educational Resources Information Center

    Ebert, Christine; Ebert, Edward S., II

    Creative thinking and how to foster it is the focus of this resource book for teachers. Part One of this book emphasizes the theoretical background of the creative thinking concept and discusses the relationship between creative thinking, problem solving, science, and technology. Part Two focuses on three levels of inventing, each examining…

  5. Activation energies control the macroscopic properties of physically cross-linked materials.

    PubMed

    Appel, Eric A; Forster, Rebecca A; Koutsioubas, Alexandros; Toprakcioglu, Chris; Scherman, Oren A

    2014-09-15

    Here we show the preparation of a series of water-based physically cross-linked polymeric materials utilizing cucurbit[8]uril (CB[8]) ternary complexes displaying a range of binding, and therefore cross-linking, dynamics. We determined that the mechanical strength of these materials is correlated directly with a high energetic barrier for the dissociation of the CB[8] ternary complex cross-links, whereas facile and rapid self-healing requires a low energetic barrier to ternary complex association. The versatile CB[8] ternary complex has, therefore, proven to be a powerful asset for improving our understanding of challenging property-structure relationships in supramolecular systems and their associated influence on the bulk behavior of dynamically cross-linked materials.

  6. Using the Activity Model of Inquiry to Enhance General Chemistry Students' Understanding of Nature of Science

    ERIC Educational Resources Information Center

    Marchlewicz, Sara C.; Wink, Donald J.

    2011-01-01

    Nature of science refers to the processes of scientific activity and the social and cultural premises involved in the creation of scientific knowledge. Having an informed view of nature of science is important in the development of scientifically literate citizens. However, students often come to the classroom with misconceptions about nature of…

  7. Glimpses of Science: Multimedia-Enhanced Hands-On Activities for Primary School Students

    ERIC Educational Resources Information Center

    Hatsidimitris, George; Connor, Rick; Ginges, Jacinda; Wolfe, Joe

    2010-01-01

    "Glimpses of Science" is the outcome of collaboration between the University of New South Wales and four primary schools in the Sydney metropolitan region. A prototype kit on the topic of sound was developed and demonstrated by the team. This kit formed the basis for further science activities to be designed and produced in conjunction with the…

  8. A Context-Aware Ubiquitous Learning Approach to Conducting Scientific Inquiry Activities in a Science Park

    ERIC Educational Resources Information Center

    Hwang, Gwo-Jen; Tsai, Chin-Chung; Chu, Hui-Chun; Kinshuk; Chen, Chieh-Yuan

    2012-01-01

    Fostering students' scientific inquiry competence has been recognised as being an important and challenging objective of science education. To strengthen the understanding of science theories or notations, researchers have suggested conducting some learning activities in the field via operating relevant devices. In a traditional infield scientific…

  9. Elements of Design-Based Science Activities That Affect Students' Motivation

    ERIC Educational Resources Information Center

    Jones, Brett D.; Chittum, Jessica R.; Akalin, Sehmuz; Schram, Asta B.; Fink, Jonathan; Schnittka, Christine; Evans, Michael A.; Brandt, Carol

    2015-01-01

    The primary purpose of this study was to examine the ways in which a 12-week after-school science and engineering program affected middle school students' motivation to engage in science and engineering activities. We used current motivation research and theory as a conceptual framework to assess 14 students' motivation through questionnaires,…

  10. Context and Activity-Based Science in Action: Some Teachers' Views of the Effects on Pupils.

    ERIC Educational Resources Information Center

    Ramsden, Judith

    1994-01-01

    Explores the perceptions of teachers of the effects on their pupils of following the Salters' Science course, a course which places particular emphasis on using a broader range of activities and increases the emphasis placed on everyday applications of science. (15 references) (Author/MKR)

  11. 3 CFR - Designation of the National Science and Technology Council to Coordinate Certain Activities Under...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 3 The President 1 2011-01-01 2011-01-01 false Designation of the National Science and Technology Council to Coordinate Certain Activities Under the Arctic Research and Policy Act of 1984 Presidential Documents Other Presidential Documents Memorandum of July 22, 2010 Designation of the National Science...

  12. Uncovering Students' Environmental Identity: An Exploration of Activities in an Environmental Science Course

    ERIC Educational Resources Information Center

    Blatt, Erica

    2014-01-01

    This study at a public high school in the Northeastern United States explores how students' environmental identities are affected by various activities in an Environmental Science course. Data was collected as part of an ethnographic study involving an Environmental Science teacher and her tenth-twelfth grade students. The results focus on…

  13. Manpower and Financial Resources Allocated to Academic Science and Engineering Activities, 1965-71.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC. Div. of Science Resources Studies.

    This report summarizes the results of the National Science Foundation's biennial survey of manpower and financial resources for scientific engineering activities at institutions of higher education, 1971. The survey was conducted by mail questionnaires sent to 2,198 universities and colleges that maintained science and engineering programs, and…

  14. A comparison of high-speed links, their commercial support and ongoing R D activities

    SciTech Connect

    Gonzalez, H.L.; Barsotti, E. ); Zimmermann, S. Rio Grande do Sul Univ., Porto Alegre, RS ); Nomachi, M.; Sasaki, O. )

    1992-10-01

    Technological advances and a demanding market have forced the development of higher bandwidth communication standards for networks, data links and busses. Most of these emerging standards are gathering enough momentum that their widespread availability and lower prices are anticipated. The hardware and software that support the physical media for most of these links is currently available, allowing the user community to implement fairly high-bandwidth data links and networks with commercial components. Also, switches needed to support these networks are available or being developed. The commercial suppose of high-bandwidth data links, networks and switching fabrics provides a powerful base for the implementation of high-bandwidth data acquisition systems. A large data acquisition system like the one for the Solenoidal Detector Collaboration (SDC) at the SSC can benefit from links and networks that support an integrated systems engineering approach, for initialization, downloading, diagnostics, monitoring, hardware integration and event data readout. The issue that our current work addresses is the possibility of having a channel/network that satisfies the requirements of an integrated data acquisition system. In this paper we present a brief description of high-speed communication links and protocols that we consider of interest for high energy physic High Performance Parallel Interface (HIPPI). Serial HIPPI, Fibre Channel (FC) and Scalable Coherent Interface (SCI). In addition, the initial work required to implement an SDC-like data acquisition system is described.

  15. A comparison of high-speed links, their commercial support and ongoing R&D activities

    SciTech Connect

    Gonzalez, H.L.; Barsotti, E.; Zimmermann, S. |; Nomachi, M.; Sasaki, O.

    1992-10-01

    Technological advances and a demanding market have forced the development of higher bandwidth communication standards for networks, data links and busses. Most of these emerging standards are gathering enough momentum that their widespread availability and lower prices are anticipated. The hardware and software that support the physical media for most of these links is currently available, allowing the user community to implement fairly high-bandwidth data links and networks with commercial components. Also, switches needed to support these networks are available or being developed. The commercial suppose of high-bandwidth data links, networks and switching fabrics provides a powerful base for the implementation of high-bandwidth data acquisition systems. A large data acquisition system like the one for the Solenoidal Detector Collaboration (SDC) at the SSC can benefit from links and networks that support an integrated systems engineering approach, for initialization, downloading, diagnostics, monitoring, hardware integration and event data readout. The issue that our current work addresses is the possibility of having a channel/network that satisfies the requirements of an integrated data acquisition system. In this paper we present a brief description of high-speed communication links and protocols that we consider of interest for high energy physic High Performance Parallel Interface (HIPPI). Serial HIPPI, Fibre Channel (FC) and Scalable Coherent Interface (SCI). In addition, the initial work required to implement an SDC-like data acquisition system is described.

  16. Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework

    EPA Science Inventory

    Driven by major scientific advances in analytical methods, biomonitoring, computation, and a newly articulated vision for a greater impact in public health, the field of exposure science is undergoing a rapid transition from a field of observation to a field of prediction. Deploy...

  17. Linking Science and Language Arts: A Review of the Literature Which Compares Integrated versus Non-Integrated Approaches

    ERIC Educational Resources Information Center

    Bradbury, Leslie U.

    2014-01-01

    The purpose of this paper is to review the literature published during the last 20 years that investigates the impact of approaches that describe themselves as integrating science and language arts on student learning and/or attitude at the elementary level. The majority of papers report that integrated approaches led to greater student…

  18. Measuring the built environment for physical activity: state of the science.

    PubMed

    Brownson, Ross C; Hoehner, Christine M; Day, Kristen; Forsyth, Ann; Sallis, James F

    2009-04-01

    Physical inactivity is one of the most important public health issues in the U.S. and internationally. Increasingly, links are being identified between various elements of the physical-or built-environment and physical activity. To understand the impact of the built environment on physical activity, the development of high-quality measures is essential. Three categories of built environment data are being used: (1) perceived measures obtained by telephone interview or self-administered questionnaires; (2) observational measures obtained using systematic observational methods (audits); and (3) archival data sets that are often layered and analyzed with GIS. This review provides a critical assessment of these three types of built-environment measures relevant to the study of physical activity. Among perceived measures, 19 questionnaires were reviewed, ranging in length from 7 to 68 questions. Twenty audit tools were reviewed that cover community environments (i.e., neighborhoods, cities), parks, and trails. For GIS-derived measures, more than 50 studies were reviewed. A large degree of variability was found in the operationalization of common GIS measures, which include population density, land-use mix, access to recreational facilities, and street pattern. This first comprehensive examination of built-environment measures demonstrates considerable progress over the past decade, showing diverse environmental variables available that use multiple modes of assessment. Most can be considered first-generation measures, so further development is needed. In particular, further research is needed to improve the technical quality of measures, understand the relevance to various population groups, and understand the utility of measures for science and public health.

  19. Linking Prenatal Androgens to Gender-Related Attitudes, Identity, and Activities: Evidence From Girls With Congenital Adrenal Hyperplasia.

    PubMed

    Endendijk, Joyce J; Beltz, Adriene M; McHale, Susan M; Bryk, Kristina; Berenbaum, Sheri A

    2016-10-01

    Key questions for developmentalists concern the origins of gender attitudes and their implications for behavior. We examined whether prenatal androgen exposure was related to gender attitudes, and whether and how the links between attitudes and gendered activity interest and participation were mediated by gender identity and moderated by hormones. Gender attitudes (i.e., gender-role attitudes and attitudes about being a girl), gender identity, and gender-typed activities were reported by 54 girls aged 10-13 years varying in degree of prenatal androgen exposure, including 40 girls with classical congenital adrenal hyperplasia (C-CAH) exposed to high prenatal androgens and 14 girls with non-classical (NC) CAH exposed to low, female-typical, prenatal androgens. Both girls with C-CAH and NC-CAH reported positive attitudes about being a girl and egalitarian gender attitudes, consistent with their female-typical gender identity. In contrast, girls with C-CAH had more male-typed activity interest and participation than girls with NC-CAH. Gender attitudes were linked to activities in both groups, with gender identity mediating the links. Specifically, gender-role attitudes and positive attitudes about being a girl were associated with feminine gender identity, which in turn was associated with decreased male-typed activity interests and participation, and increased female-typed activity interests. Our results are consistent with schema theories, with attitudes more closely associated with gender identity than with prenatal androgens. PMID:26940967

  20. Linking Prenatal Androgens to Gender-Related Attitudes, Identity, and Activities: Evidence From Girls With Congenital Adrenal Hyperplasia.

    PubMed

    Endendijk, Joyce J; Beltz, Adriene M; McHale, Susan M; Bryk, Kristina; Berenbaum, Sheri A

    2016-10-01

    Key questions for developmentalists concern the origins of gender attitudes and their implications for behavior. We examined whether prenatal androgen exposure was related to gender attitudes, and whether and how the links between attitudes and gendered activity interest and participation were mediated by gender identity and moderated by hormones. Gender attitudes (i.e., gender-role attitudes and attitudes about being a girl), gender identity, and gender-typed activities were reported by 54 girls aged 10-13 years varying in degree of prenatal androgen exposure, including 40 girls with classical congenital adrenal hyperplasia (C-CAH) exposed to high prenatal androgens and 14 girls with non-classical (NC) CAH exposed to low, female-typical, prenatal androgens. Both girls with C-CAH and NC-CAH reported positive attitudes about being a girl and egalitarian gender attitudes, consistent with their female-typical gender identity. In contrast, girls with C-CAH had more male-typed activity interest and participation than girls with NC-CAH. Gender attitudes were linked to activities in both groups, with gender identity mediating the links. Specifically, gender-role attitudes and positive attitudes about being a girl were associated with feminine gender identity, which in turn was associated with decreased male-typed activity interests and participation, and increased female-typed activity interests. Our results are consistent with schema theories, with attitudes more closely associated with gender identity than with prenatal androgens.

  1. The Effects of Aesthetic Science Activities on Improving At-Risk Families Children's Anxiety about Learning Science and Positive Thinking

    ERIC Educational Resources Information Center

    Hong, Zuway-R.; Lin, Huann-Shyang; Chen, Hsiang-Ting; Wang, Hsin-Hui; Lin, Chia-Jung

    2014-01-01

    The purpose of this study was to explore the effects of aesthetic science activities on improving elementary school at-risk families' children's positive thinking, attitudes toward science, and decreasing their anxiety about learning science. Thirty-six 4th-grade children from at-risk families volunteered to participate in a 12-week…

  2. 48 CFR 1852.228-78 - Cross-waiver of liability for science or space exploration activities unrelated to the...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... for science or space exploration activities unrelated to the International Space Station. 1852.228-78... Cross-waiver of liability for science or space exploration activities unrelated to the International... Liability for Science or Space Exploration Activities Unrelated to the International Space Station (OCT...

  3. 48 CFR 1852.228-78 - Cross-waiver of liability for science or space exploration activities unrelated to the...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... for science or space exploration activities unrelated to the International Space Station. 1852.228-78... Cross-waiver of liability for science or space exploration activities unrelated to the International... Liability for Science or Space Exploration Activities Unrelated to the International Space Station (OCT...

  4. Roller Coaster Science.

    ERIC Educational Resources Information Center

    Sumners, Carolyn; Jones, Howard L.

    1983-01-01

    Discusses the science of roller coasters, relating gravity, potential/kinetic energy, inertia, and centripetal force to the various parts of the ride, providing tips on linking classroom discussions to field trips. Includes sample student activity sheet and source for additional units using amusement park rides/playground activities to teach…

  5. Science.

    ERIC Educational Resources Information Center

    Roach, Linda E., Ed.

    This document contains the following papers on science instruction and technology: "A 3-D Journey in Space: A New Visual Cognitive Adventure" (Yoav Yair, Rachel Mintz, and Shai Litvak); "Using Collaborative Inquiry and Interactive Technologies in an Environmental Science Project for Middle School Teachers: A Description and Analysis" (Patricia…

  6. Communist purges of Soviet Academy of Sciences members and solar activity

    NASA Astrophysics Data System (ADS)

    Tomilin, Konstantin A.

    The author is investigating the corelation between the intansity of Communsit purges under Members of the Academy of Sciences of USSR and Solar Activity, based on previous researches by Alexander Leonidovich Chizhevskij (1897-1964).

  7. Exploring Dietary Kilocalories: An Activity Exemplifying the Personal Value of Science and Mathematics.

    ERIC Educational Resources Information Center

    Rye, James A.

    1999-01-01

    Presents an activity that integrates mathematics and science and focuses on estimation, percent, proportionality, ratio, interconverting units, deriving algorithms mathematically, energy transformation, interactions of energy and matter, bioavailability, composition, density, inferring, and data gathering through scientific interpretation.…

  8. Rutherford's Enlarged: A Content-Embedded Activity To Teach about Nature of Science.

    ERIC Educational Resources Information Center

    Abd-El-Khalick, Fouad

    2002-01-01

    Describes an activity that can be used to help middle and secondary school students develop more informed understandings of some important aspects of the nature of science in the context of teaching Rutherford's experiments and atomic structure. (Author/MM)

  9. Astronomical activities of the Apollo orbital science photographic team

    NASA Technical Reports Server (NTRS)

    Mercer, R. D.

    1974-01-01

    A partial accounting of Apollo Orbital Science Photographic Team (APST) work is presented as reported by one of its members who provided scientific recommendations for, guidance in, and reviews of photography in astronomy. Background on the formation of the team and its functions and management are discussed. It is concluded that the APST clearly performed the overall objective for which it was established - to improve the scientific value of the Apollo lunar missions. Specific reasons for this success are given.

  10. Activities of the Research Institute for Advanced Computer Science

    NASA Technical Reports Server (NTRS)

    Oliger, Joseph

    1994-01-01

    The Research Institute for Advanced Computer Science (RIACS) was established by the Universities Space Research Association (USRA) at the NASA Ames Research Center (ARC) on June 6, 1983. RIACS is privately operated by USRA, a consortium of universities with research programs in the aerospace sciences, under contract with NASA. The primary mission of RIACS is to provide research and expertise in computer science and scientific computing to support the scientific missions of NASA ARC. The research carried out at RIACS must change its emphasis from year to year in response to NASA ARC's changing needs and technological opportunities. Research at RIACS is currently being done in the following areas: (1) parallel computing; (2) advanced methods for scientific computing; (3) high performance networks; and (4) learning systems. RIACS technical reports are usually preprints of manuscripts that have been submitted to research journals or conference proceedings. A list of these reports for the period January 1, 1994 through December 31, 1994 is in the Reports and Abstracts section of this report.

  11. Using Students' Science Ideas to Drive Instruction: How Responsive Teaching Shapes Learning Activity

    NASA Astrophysics Data System (ADS)

    Canavesi, Cristina

    Teaching in a way that is responsive to students' science ideas creates opportunities for meaningful, rigorous sense-making in a way that traditional science teaching does not. In this study, the researcher, as a visiting teacher, taught the same three-week circuits unit to one fourth grade class and two fifth grade classes from a responsive teaching stance. The teachers' attention to and incorporation of students' science ideas shifted unit trajectories and uniquely shaped the ongoing learning activity within whole-group discourse. A unit-level analysis of the frequency and category of science concepts present in whole-group discourse shows that all three classes discussed the same science concepts by the end of the unit; however, when these ideas presented themselves within whole group discourse differed across time, even though students were engaged in the same lessons. Tensions and dilemmas of responsive science teaching are discussed.

  12. Using Analog Field Tests To Link and Prepare Science and In-Situ Resource Utilization for Future Space Missions

    NASA Technical Reports Server (NTRS)

    Sanders, Gerald B.

    2010-01-01

    A major goal of NASA s human exploration program is to learn how to use the resources of space, known as In-Situ Resource Utilization (ISRU), to lower the cost and risk of human space exploration. Successful implementation of ISRU requires detailed knowledge of surface and subsurface materials, minerals, and volatiles that may be present. This same information is required to better understand the physical and geologic composition, structure, origin, and evolution of the Moon, Mars, and other extraterrestrial bodies of interest. It is also important to recognize that while ISRU and science objectives may be similar, the desired method or hardware to achieve the information desired may be drastically different. One method to promote understanding, coordination, and joint development of instruments and operations between Science and ISRU is the use of analog field demonstrations.

  13. Hands-On Life Science Activities for Middle Schools. Teacher's Edition. First Edition.

    ERIC Educational Resources Information Center

    Newman, Barbara; Kramer, Stephanie

    This book provides 50 enrichment activities for the science curriculum that provide concrete connections with important world events. Each activity is self-contained and provides everything the student needs to gain a basic understanding of a concept or to work through a project. The activities include innovative and traditional projects for both…

  14. The STRATegy COLUMN for Precollege Science Teachers: Volcanic Activity.

    ERIC Educational Resources Information Center

    Metzger, Ellen Pletcher

    1995-01-01

    Describes resources for information and activities involving volcanoes. Includes an activity that helps students become familiar with the principal types of volcanoes and explores how the viscosity of magma affects the way a volcano erupts. (MKR)

  15. Out-of-School Science Activities for Young People.

    ERIC Educational Resources Information Center

    Stevens, R. A.

    This handbook represents an attempt by UNESCO to give a broad picture of the kinds of out-of-school activities that are designed to engage the participation of young people in different parts of the world. Out-of-school activities, as used in this publication, refers to educational activities undertaken or done outside the formal teaching periods…

  16. Nitrate Water Activities, Science Study Aid No. 4.

    ERIC Educational Resources Information Center

    Agricultural Research Service (USDA), Washington, DC.

    Intended to supplement a regular program, this pamphlet provides background information, related activities, and suggestions for other activities on the subject of nitrate as a water pollutant. Two activities related to plant nutrient pollution, nitrate filtration and measuring mitrate used by plants, are explained in detail, outlining objectives,…

  17. Crew activities, science, and hazards of manned missions to Mars

    NASA Technical Reports Server (NTRS)

    Clark, Benton C.

    1988-01-01

    The crew scientific and nonscientific activities that will occur at each stage of a mission to Mars are examined. Crew activities during the interplanetary flight phase will include simulations, maintenance and monitoring, communications, upgrading procedures and operations, solar activity monitoring, cross-training and sharpening of skills, physical conditioning, and free-time activities. Scientific activities will address human physiology, human psychology, sociology, astronomy, space environment effects, manufacturing, and space agriculture. Crew activities on the Martian surface will include exploration, construction, manufacturing, food production, maintenance and training, and free time. Studies of Martian geology and atmosphere, of the life forms that may exist there, and of the Martian moons will occur on the planet's surface. Crew activities and scientific studies that will occur in Mars orbit, and the hazards relevant to each stage of the mission, are also addressed.

  18. Human Sciences Activity Characteristics and Reviewer Evaluation File, HSACRE. User's Guide for the Machine-Readable Data File.

    ERIC Educational Resources Information Center

    Robinson, James T.; Tolman, Richard R.

    The Biological Sciences Curriculum Study (BSCS) Human Sciences Project developed, produced, and field tested 13 interdisciplinary, non-traditional, non-text science curriculum modules for early adolescents, ages 11 to 14. The Codebook for Human Sciences Activity Characteristics on Reviewer Evaluation File--HSACRE (ED 211 384) contains 8 variables…

  19. Linking observations at active volcanoes to physical processes through conduit flow modelling

    NASA Astrophysics Data System (ADS)

    Thomas, Mark; Neuberg, Jurgen

    2010-05-01

    of the Low frequency events observed on Montserrat is their tightly confined source region. The high degree of similarity of the waveforms from such events indicates a stationary common source within a finite volume of 150m x 150m x 150m (Neuberg et al., 2006). By modelling the physical processes that occur at depth within the volcano it has been possible to identify a potential source region of these events caused by the shape of the conduit, that has a fixed position and will have the potential cause repeatable events whenever magma is moving within the system. Making links of this type is essential to form a better understanding of what the observations made by monitoring systems actually relate to in terms of the volcanoes activity. Tuffen, H., Dingwell, D.B., and Pinkerton, H. 2003. Repeated fracture and healing of silicic magma generate flow banding and earthquakes? Geology, 31(12), 1089-1092. Collier, L. and Neuberg, J. 2006. Incorporating seismic observations into 2D conduit flow modelling. Journal of volcanology and geothermal research, 152, 331-346. Neuberg, J., Tuffen, H., Collier, L., Green, D., Powell, T., and Dingwell, P. 2006. The trigger mechanisms of low-frequency swarms on Montserrat. Journal of volcanology and geothermal research, 153, 37-50.

  20. Transglutaminase cross-linking effect on sensory characteristics and antioxidant activities of Maillard reaction products from soybean protein hydrolysates.

    PubMed

    Song, Na; Tan, Chen; Huang, Meigui; Liu, Ping; Eric, Karangwa; Zhang, Xiaoming; Xia, Shuqin; Jia, Chengsheng

    2013-01-01

    To improve the yield of Maillard peptides, a microbial transglutaminase (MTGase) was used to increase the content of 1000-5000Da peptides in soybean protein hydrolysates by using a cross-linking reaction. The sensory characteristics and antioxidant activities of corresponding Maillard Reaction Products (MSPC) was then evaluated. After cross-linking treatment the content of 1000-5000Da peptides in protein hydrolysates and the yield of Maillard peptides increased by 21.19% and 8.71%, respectively, which contributed to the improved mouthfulness of MSPC. The bitter amino acids were significantly decreased and the umami acids were markedly increased in MSPC. Volatile compounds identified by GC-MS analysis showed that the content of the important meaty flavour compounds (such as 2-methyl-3-furanthiol, bis(2-methyl-3-furyl)disulfide) of MSPC were dramatically higher than that of MRPs from uncross-linking peptides. Combined with sensory evaluation, it was confirmed that MTGase cross-linking improved the flavour Characteristics and did not affect the antioxidant activity of MSPC.