Science.gov

Sample records for activities resources required

  1. Institutional Resource Requirements, Management, and Accountability.

    ERIC Educational Resources Information Center

    Matlock, John; Humphries, Frederick S.

    A detailed resource management study was conducted at Tennessee State University, and resource management problems at other higher education institutions were identified through the exchange of data and studies. Resource requirements and management problems unique to black institutions were examined, as were the problems that arise from regional…

  2. Lunar resource recovery: A definition of requirements

    NASA Technical Reports Server (NTRS)

    Elsworth, D.; Kohler, J. L.; Alexander, S. S.

    1992-01-01

    The capability to locate, mine, and process the natural resources of the Moon will be an essential requirement for lunar base development and operation. The list of materials that will be necessary is extensive and ranges from oxygen and hydrogen for fuel and life support to process tailings for emplacement over habitats. Despite the resources need, little is known about methodologies that might be suitable for utilizing lunar resources. This paper examines some of the requirements and constraints for resource recovery and identifies key areas of research needed to locate, mine, and process extraterrestrial natural resources.

  3. FY 2001-2002 Mission Resource Requirements.

    ERIC Educational Resources Information Center

    South Carolina Commission on Higher Education, Columbia.

    This document describes the performance funding mission resource requirements for public institutions of higher education in South Carolina. It opens with sections of the state code, as amended in 1993, that define the annual budget requests of higher education institutions and outline the requirements for performance funding. The guiding…

  4. FIREX mission requirements document for renewable resources

    NASA Technical Reports Server (NTRS)

    Carsey, F.; Dixon, T.

    1982-01-01

    The initial experimental program and mission requirements for a satellite synthetic aperture radar (SAR) system FIREX (Free-Flying Imaging Radar Experiment) for renewable resources is described. The spacecraft SAR is a C-band and L-band VV polarized system operating at two angles of incidence which is designated as a research instrument for crop identification, crop canopy condition assessments, soil moisture condition estimation, forestry type and condition assessments, snow water equivalent and snow wetness assessments, wetland and coastal land type identification and mapping, flood extent mapping, and assessment of drainage characteristics of watersheds for water resources applications. Specific mission design issues such as the preferred incidence angles for vegetation canopy measurements and the utility of a dual frequency (L and C-band) or dual polarization system as compared to the baseline system are addressed.

  5. Resources required for topological quantum factoring

    SciTech Connect

    Baraban, M.; Bonesteel, N. E.; Simon, S. H.

    2010-06-15

    We consider a hypothetical topological quantum computer composed of either Ising or Fibonacci anyons. For each case, we calculate the time and number of qubits (space) necessary to execute the most computationally expensive step of Shor's algorithm, modular exponentiation. For Ising anyons, we apply Bravyi's distillation method [S. Bravyi, Phys. Rev. A 73, 042313 (2006)] which combines topological and nontopological operations to allow for universal quantum computation. With reasonable restrictions on the physical parameters we find that factoring a 128-bit number requires approximately 10{sup 3} Fibonacci anyons versus at least 3x10{sup 9} Ising anyons. Other distillation algorithms could reduce the resources for Ising anyons substantially.

  6. FIREX mission requirements document for nonrenewable resources

    NASA Technical Reports Server (NTRS)

    Dixon, T.; Carsey, F.

    1982-01-01

    The proposed mission requirements and a proposed experimental program for satellite synthetic aperture radar (SAR) system named FIREX (Free-Flying Imaging Radar Experiment) for nonrenewable resources is described. The recommended spacecraft minimum SAR system is a C-band imager operating in four modes: (1) low look angle HH-polarized; (2) intermediate look angle, HH-polarized; (3) intermediate look angle, IIV-polarized; and (4) high look angle HH-polarized. This SAR system is complementary to other future spaceborne imagers such as the Thematic Mapper on LANDSAT-D. A near term aircraft SAR based research program is outlined which addresses specific mission design issues such as preferred incidence angles or polarizations for geologic targets of interest.

  7. 14 CFR 1274.904 - Resource sharing requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Resource sharing requirements. 1274.904... AGREEMENTS WITH COMMERCIAL FIRMS Other Provisions and Special Conditions § 1274.904 Resource sharing requirements. Resource Sharing Requirements July 2002 Where NASA and other Government agencies are involved...

  8. 14 CFR 1274.904 - Resource sharing requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Resource sharing requirements. 1274.904... AGREEMENTS WITH COMMERCIAL FIRMS Other Provisions and Special Conditions § 1274.904 Resource sharing requirements. Resource Sharing Requirements July 2002 Where NASA and other Government agencies are involved...

  9. 14 CFR 1274.904 - Resource sharing requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Resource sharing requirements. 1274.904... AGREEMENTS WITH COMMERCIAL FIRMS Other Provisions and Special Conditions § 1274.904 Resource sharing requirements. Resource Sharing Requirements July 2002 Where NASA and other Government agencies are involved...

  10. 14 CFR 1274.904 - Resource sharing requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Resource sharing requirements. 1274.904... AGREEMENTS WITH COMMERCIAL FIRMS Other Provisions and Special Conditions § 1274.904 Resource sharing requirements. Resource Sharing Requirements July 2002 Where NASA and other Government agencies are involved...

  11. 14 CFR § 1274.904 - Resource sharing requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Resource sharing requirements. § 1274.904... AGREEMENTS WITH COMMERCIAL FIRMS Other Provisions and Special Conditions § 1274.904 Resource sharing requirements. Resource Sharing Requirements July 2002 Where NASA and other Government agencies are involved...

  12. Resource Requirements for Online Learning Environments.

    ERIC Educational Resources Information Center

    Dringus, Laurie P.

    1999-01-01

    Discussion of online instruction that is delivered via dedicated Web-based hypertext systems on the Internet focuses on the human resources (including faculty, students, administration, and staff), information and learning resources, and technical resources that are needed to produce and manage online learning environments. Describes future…

  13. Space Station Freedom resource allocation accommodation of technology payload requirements

    NASA Technical Reports Server (NTRS)

    Avery, Don E.; Collier, Lisa D.; Gartrell, Charles F.

    1990-01-01

    An overview of the Office of Aeronautics, Exploration, and Technology (OAET) Space Station Freedom Technology Payload Development Program is provided, and the OAET Station resource requirements are reviewed. The requirements are contrasted with current proposed resource allocations. A discussion of the issues and conclusions are provided. It is concluded that an overall 20 percent resource allocation is appropriate to support OAET's technology development program, that some resources are inadequate even at the 20 percent level, and that bartering resources among U.S. users and international partners and increasing the level of automation may be viable solutions to the resource constraint problem.

  14. Spacelab user implementation assessment study. Volume 3: Resource requirements development

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The resources requirements for the integration and checkout of spacelab payloads are presented in three categories: mission-unique, sustaining, and non-recurring. The requirements are identified by concept and by center. Cost estimates for the resource requirements are also presented.

  15. 18 CFR 390.2 - Activities requiring registration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Activities requiring registration. 390.2 Section 390.2 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES ELECTRONIC REGISTRATION § 390.2 Activities requiring registration. (a) Electronic registration is...

  16. Youth Physical Activity Resources Use and Activity Measured by Accelerometry

    PubMed Central

    Maslow, Andréa L.; Colabianchi, Natalie

    2014-01-01

    Objectives To examine whether utilization of physical activity resources (eg, parks) was associated with daily physical activity measured by accelerometry. Methods 111 adolescents completed a travel diary with concurrent accelerometry. The main exposure was self-reported utilization of a physical activity resource (none/1+ resources). The main outcomes were total minutes spent in daily 1) moderate-vigorous physical activity and 2) vigorous physical activity. Results Utilizing a physical activity resource was significantly associated with total minutes in moderate-vigorous physical activity. African-Americans and males had significantly greater moderate-vigorous physical activity. Conclusions Results from this study support the development and use of physical activity resources. PMID:21204684

  17. Spacelab mission dependent training parametric resource requirements study

    NASA Technical Reports Server (NTRS)

    Ogden, D. H.; Watters, H.; Steadman, J.; Conrad, L.

    1976-01-01

    Training flows were developed for typical missions, resource relationships analyzed, and scheduling optimization algorithms defined. Parametric analyses were performed to study the effect of potential changes in mission model, mission complexity and training time required on the resource quantities required to support training of payload or mission specialists. Typical results of these analyses are presented both in graphic and tabular form.

  18. 75 FR 63113 - Financial Resources Requirements for Derivatives Clearing Organizations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... number of small entities. \\17\\ 5 U.S.C. 601 et seq. \\18\\ 47 FR 18618 (Apr. 30, 1982). \\19\\ See 66 FR... COMMISSION 17 CFR Parts 39 and 140 RIN 3038-AC98, 3038-AD02 Financial Resources Requirements for Derivatives... Protection Act (Dodd-Frank Act). The proposed regulations establish financial resources requirements...

  19. 15 CFR 971.420 - Resource conservation requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 3 2013-01-01 2013-01-01 false Resource conservation requirements. 971.420 Section 971.420 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... conservation requirements. For the purpose of conservation of natural resources, each permit issued under...

  20. 15 CFR 970.519 - Resource conservation requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 3 2014-01-01 2014-01-01 false Resource conservation requirements. 970.519 Section 970.519 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... conservation requirements. For the purpose of conservation of natural resources, each license issued under...

  1. 15 CFR 971.420 - Resource conservation requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Resource conservation requirements. 971.420 Section 971.420 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... conservation requirements. For the purpose of conservation of natural resources, each permit issued under...

  2. 15 CFR 970.519 - Resource conservation requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Resource conservation requirements. 970.519 Section 970.519 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... conservation requirements. For the purpose of conservation of natural resources, each license issued under...

  3. 15 CFR 971.420 - Resource conservation requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Resource conservation requirements. 971.420 Section 971.420 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... conservation requirements. For the purpose of conservation of natural resources, each permit issued under...

  4. 15 CFR 970.519 - Resource conservation requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 3 2013-01-01 2013-01-01 false Resource conservation requirements. 970.519 Section 970.519 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... conservation requirements. For the purpose of conservation of natural resources, each license issued under...

  5. 15 CFR 970.519 - Resource conservation requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 3 2012-01-01 2012-01-01 false Resource conservation requirements. 970.519 Section 970.519 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... conservation requirements. For the purpose of conservation of natural resources, each license issued under...

  6. 15 CFR 970.519 - Resource conservation requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Resource conservation requirements. 970.519 Section 970.519 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... conservation requirements. For the purpose of conservation of natural resources, each license issued under...

  7. 15 CFR 971.420 - Resource conservation requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 3 2014-01-01 2014-01-01 false Resource conservation requirements. 971.420 Section 971.420 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... conservation requirements. For the purpose of conservation of natural resources, each permit issued under...

  8. 15 CFR 971.420 - Resource conservation requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 3 2012-01-01 2012-01-01 false Resource conservation requirements. 971.420 Section 971.420 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... conservation requirements. For the purpose of conservation of natural resources, each permit issued under...

  9. Assessment of Geothermal Data Resources and Requirements

    SciTech Connect

    none,

    2008-09-01

    This paper is a review of Geothermal Technologies Program activities and archives related to data collection and analysis. It includes an assessment of the current state of geothermal data, future program and stakeholder data needs, existence of and access to critical data, and high-level direction and prioritization of next steps to meet the Program’s data needs.

  10. Youth Physical Activity Resource Use and Activity Measured by Accelerometry

    ERIC Educational Resources Information Center

    Maslow, Andra L.; Colabianchi, Natalie

    2011-01-01

    Objectives: To examine whether use of physical activity resources (e.g., parks) was associated with daily physical activity measured by accelerometry. Methods: One hundred eleven adolescents completed a travel diary with concurrent accelerometry. The main exposure was self-reported use of a physical activity resource (none /1 resources). The main…

  11. Geothermal resource requirements for an energy self-sufficient spaceport

    SciTech Connect

    Kruger, P.; Fioravanti, M.; Duchane, D.; Vaughan, A.

    1997-01-01

    Geothermal resources in the southwestern United States provide an opportunity for development of isolated spaceports with local energy self-sufficiency. Geothermal resources can provide both thermal energy and electrical energy for the spaceport facility infrastructure and production of hydrogen fuel for the space vehicles. In contrast to hydrothermal resources by which electric power is generated for sale to utilities, hot dry rock (HDR) geothermal resources are more wide-spread and can be more readily developed at desired spaceport locations. This paper reviews a dynamic model used to quantify the HDR resources requirements for a generic spaceport and estimate the necessary reservoir size and heat extraction rate. The paper reviews the distribution of HDR resources in southern California and southern New Mexico, two regions where a first developmental spaceport is likely to be located. Finally, the paper discusses the design of a HDR facility for the generic spaceport and estimates the cost of the locally produced power.

  12. Functional Requirements for Information Resource Provenance on the Web

    SciTech Connect

    McCusker, James P.; Lebo, Timothy; Graves, Alvaro; Difranzo, Dominic; Pinheiro da Silva, Paulo; McGuinness, Deborah L.

    2012-06-19

    We provide a means to formally explain the relationship between HTTP URLs and the representations returned when they are requested. According to existing World Wide Web architecture, the URL serves as an identier for a semiotic referent while the document returned via HTTP serves as a representation of the same referent. This begins with two sides of a semiotic triangle; the third side is the relationship between the URL and the representation received. We complete this description by extending the library science resource model Functional Requirements for Bibliographic Resources (FRBR) with cryptographic message and content digests to create a Functional Requirements for Information Resources (FRIR). We show how applying the FRIR model to HTTP GET and POST transactions disambiguates the many relationships between a given URL and all representations received from its request, provides fine-grained explanations that are complementary to existing explanations of web resources, and integrates easily into the emerging W3C provenance standard.

  13. Earth resources mission performance studies. Volume 1: Requirements definition

    NASA Technical Reports Server (NTRS)

    1974-01-01

    The need for a realistic set of earth resources collection requirements to test and maximize the data gathering capabilities of the EOS remote sensor systems is considered. The collection requirements will be derived from established user requirements. In order to confine and bound the requirements study, some baseline assumptions were established. These are: (1) image acquisition is confined to the contiguous United States, (2) the fundamental data users are select participating federal agencies, (3) the acquired data will be applied to generating information necessary or in support of existing federal agency charters, and (4) the most pressing or desired federal agency earth resources data requirements have been defined, suggested, or implied in current available literature.

  14. Activation of nonlocal quantum resources.

    PubMed

    Navascués, Miguel; Vértesi, Tamás

    2011-02-11

    We find two two-qubit bipartite states ρ1, ρ2 such that arbitrarily many copies of one or the other cannot exhibit nonlocal correlations in a two-setting-two-outcome Bell scenario. However, the bipartite state ρ1 ⊗ ρ2 violates the Clauser-Horne-Shimony-Holt (CHSH) Bell inequality [J. F. Clauser, M. A. Horne, A. Shimony, and R. A. Holt, Phys. Rev. Lett. 23, 880 (1969).] by an amount of 2.023. We also identify a CHSH-local state ρ such that ρ⊗2 is CHSH inequality-violating. The tools employed can be easily adapted to find instances of nonlocality activation in arbitrary Bell scenarios. PMID:21405447

  15. Nurses' perceptions of patients' requirements for nursing resources.

    PubMed

    Dunn, Sandra V; Schmitz, Karl

    2005-01-01

    The study used semi-structured interviews in an interpretive research design to explore nurses' perceptions of patients requiring disproportionate amounts of nursing resources, and factors influencing those perceptions. A total of 50 senior nurses from a variety of medical and surgical settings, including a high dependency unit, were interviewed and the data analysed to determine common themes and differences between participants. The four major themes of patient characteristics, family needs, staffing and organisational context defined the factors nurses perceived as influencing their perceptions of patients' dependency. Patient requirements for nursing resources were seen as a continuum rather than a specific point, and were balanced on the combined influences of the four themes. At times, demands imposed on nursing resources lead to nurses' perceptions of delivering less than ideal care, stress and frustration. The latter applied particularly to factors that were outside of the control of nurses such as staffing levels and skill mix. PMID:16499239

  16. RoboResource Technology Learning Activities.

    ERIC Educational Resources Information Center

    Keck, Tom, Comp.; Frye, Ellen, Ed.

    Preparing students to be successful in a rapidly changing world means showing them how to use the tools of technology and how to integrate those tools into all areas of learning. This booklet is divided into three sections: Design Activities, Experiments, and Resources. The design activities ask students to collaborate on design projects. In these…

  17. Design requirements for operational earth resources ground data processing

    NASA Technical Reports Server (NTRS)

    Baldwin, C. J.; Bradford, L. H.; Burnett, E. S.; Hutson, D. E.; Kinsler, B. A.; Kugle, D. R.; Webber, D. S.

    1972-01-01

    Realistic tradeoff data and evaluation techniques were studied that permit conceptual design of operational earth resources ground processing systems. Methodology for determining user requirements that utilize the limited information available from users is presented along with definitions of sensor capabilities projected into the shuttle/station era. A tentative method is presented for synthesizing candidate ground processing concepts.

  18. Education Requirements for Natural Resource Based Outdoor Recreation Professionals.

    ERIC Educational Resources Information Center

    Elsner, Gary; And Others

    The Office of Personnel Management should designate a new professional series for hiring individuals in outdoor recreational management. A new professional series would help set a standard for professionals with training in both resource management and the social sciences. Recommended educational requirements for the series include: (1) natural…

  19. Implementing a Resource Requirements Prediction Model in Community Colleges.

    ERIC Educational Resources Information Center

    Rice, Gary Alan

    The purposes of this study were to determine what characterizes a useful cost estimating model at the community college level, to implement at a community college the Resource Requirements Prediction Model 1.6 (RRPM) developed by the National Center for Higher Education Management Systems, to identify problems associated with implementation and…

  20. Resource Requirements Planning for Hospitals Treating Serious Infectious Disease Cases.

    SciTech Connect

    Vugrin, Eric D.; Verzi, Stephen Joseph; Finley, Patrick D.; Turnquist, Mark A.; Wyte-Lake, Tamar; Griffin, Ann R.; Ricci, Karen J.; Plotinsky, Rachel

    2015-02-01

    This report presents a mathematical model of the way in which a hospital uses a variety of resources, utilities and consumables to provide care to a set of in-patients, and how that hospital might adapt to provide treatment to a few patients with a serious infectious disease, like the Ebola virus. The intended purpose of the model is to support requirements planning studies, so that hospitals may be better prepared for situations that are likely to strain their available resources. The current model is a prototype designed to present the basic structural elements of a requirements planning analysis. Some simple illustrati ve experiments establish the mo del's general capabilities. With additional inve stment in model enhancement a nd calibration, this prototype could be developed into a useful planning tool for ho spital administrators and health care policy makers.

  1. Resource requirements for a fault-tolerant quantum Fourier transform

    NASA Astrophysics Data System (ADS)

    Goto, Hayato

    2014-11-01

    We investigate resource requirements for a fault-tolerant quantum Fourier transform. The quantum Fourier transform is a basic subroutine for quantum algorithms which provide an exponential speedup over known classical ones, such as Shor's algorithm for factoring. To implement single-qubit rotations required for a quantum Fourier transform in a fault-tolerant manner, we consider two types of approaches: gate synthesis and state distillation. While the gate synthesis approximates single-qubit rotations with basic quantum operations, the state distillation allows one to perform single-qubit rotations for a quantum Fourier transform exactly. It is unknown, however, which approach is better for a quantum Fourier transform. Here we develop a state-distillation method optimized for a quantum Fourier transform and compare this performance with those of state-of-the-art techniques for gate synthesis without and with ancillary states (ancillas). The performance is evaluated with the resource requirement for a quantum Fourier transform. The resource is measured by the total number of π /8 gates denoted by T , which is called the T count. Contrary to the expectation, the T count for the state distillation is considerably larger than those for the ancilla-free and ancilla-assisted gate synthesis. Thus, we conclude that the ancilla-assisted gate synthesis is a better approach to a fault-tolerant quantum Fourier transform.

  2. Resource requirements of the Pacific leatherback turtle population.

    PubMed

    Jones, T Todd; Bostrom, Brian L; Hastings, Mervin D; Van Houtan, Kyle S; Pauly, Daniel; Jones, David R

    2012-01-01

    The Pacific population of leatherback sea turtles (Dermochelys coriacea) has drastically declined in the last 25 years. This decline has been linked to incidental capture by fisheries, egg and meat harvesting, and recently, to climate variability and resource limitation. Here we couple growth rates with feeding experiments and food intake functions to estimate daily energy requirements of leatherbacks throughout their development. We then estimate mortality rates from available data, enabling us to raise food intake (energy requirements) of the individual to the population level. We place energy requirements in context of available resources (i.e., gelatinous zooplankton abundance). Estimated consumption rates suggest that a single leatherback will eat upward of 1000 metric tonnes (t) of jellyfish in its lifetime (range 924-1112) with the Pacific population consuming 2.1×10(6) t of jellyfish annually (range 1.0-3.7×10(6)) equivalent to 4.2×10(8) megajoules (MJ) (range 2.0-7.4×10(8)). Model estimates suggest 2-7 yr-old juveniles comprise the majority of the Pacific leatherback population biomass and account for most of the jellyfish consumption (1.1×10(6) t of jellyfish or 2.2×10(8) MJ per year). Leatherbacks are large gelatinous zooplanktivores with consumption to biomass ratios of 96 (up to 192 if feeding strictly on low energy density Cnidarians); they, therefore, have a large capacity to impact gelatinous zooplankton landscapes. Understanding the leatherback's needs for gelatinous zooplankton, versus the availability of these resources, can help us better assess population trends and the influence of climate induced resource limitations to reproductive output. PMID:23071518

  3. Resource Requirements of the Pacific Leatherback Turtle Population

    PubMed Central

    Jones, T. Todd; Bostrom, Brian L.; Hastings, Mervin D.; Van Houtan, Kyle S.; Pauly, Daniel; Jones, David R.

    2012-01-01

    The Pacific population of leatherback sea turtles (Dermochelys coriacea) has drastically declined in the last 25 years. This decline has been linked to incidental capture by fisheries, egg and meat harvesting, and recently, to climate variability and resource limitation. Here we couple growth rates with feeding experiments and food intake functions to estimate daily energy requirements of leatherbacks throughout their development. We then estimate mortality rates from available data, enabling us to raise food intake (energy requirements) of the individual to the population level. We place energy requirements in context of available resources (i.e., gelatinous zooplankton abundance). Estimated consumption rates suggest that a single leatherback will eat upward of 1000 metric tonnes (t) of jellyfish in its lifetime (range 924–1112) with the Pacific population consuming 2.1×106 t of jellyfish annually (range 1.0–3.7×106) equivalent to 4.2×108 megajoules (MJ) (range 2.0–7.4×108). Model estimates suggest 2–7 yr-old juveniles comprise the majority of the Pacific leatherback population biomass and account for most of the jellyfish consumption (1.1×106 t of jellyfish or 2.2×108 MJ per year). Leatherbacks are large gelatinous zooplanktivores with consumption to biomass ratios of 96 (up to 192 if feeding strictly on low energy density Cnidarians); they, therefore, have a large capacity to impact gelatinous zooplankton landscapes. Understanding the leatherback's needs for gelatinous zooplankton, versus the availability of these resources, can help us better assess population trends and the influence of climate induced resource limitations to reproductive output. PMID:23071518

  4. Front Range Infrastructure Resources Project: water-resources activities

    USGS Publications Warehouse

    Robson, Stanley G.; Heiny, Janet S.

    1998-01-01

    Infrastructure, such as roads, buildings, airports, and dams, is built and maintained by use of large quantities of natural resources such as aggregate (sand and gravel), energy, and water. As urban area expand, local sources of these resource are becoming inaccessible (gravel cannot be mined from under a subdivision, for example), or the cost of recovery of the resource becomes prohibitive (oil and gas drilling in urban areas is costly), or the resources may become unfit for some use (pollution of ground water may preclude its use as a water supply). Governmental land-use decision and environmental mandates can further preclude development of natural resources. If infrastructure resources are to remain economically available. current resource information must be available for use in well-reasoned decisions bout future land use. Ground water is an infrastructure resource that is present in shallow aquifers and deeper bedrock aquifers that underlie much of the 2,450-square-mile demonstration area of the Colorado Front Range Infrastructure Resources Project. In 1996, mapping of the area's ground-water resources was undertaken as a U.S. Geological Survey project in cooperation with the Colorado Department of Natural Resources, Division of Water Resources, and the Colorado Water Conservation Board.

  5. 43 CFR 1784.6-1 - Resource advisory councils-requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Resource advisory councils-requirements... Advisory Committees § 1784.6-1 Resource advisory councils—requirements. (a) Resource advisory councils... participation. (b) A resource advisory council advises the Bureau of Land Management official to whom it...

  6. 43 CFR 1784.6-1 - Resource advisory councils-requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Resource advisory councils-requirements... Advisory Committees § 1784.6-1 Resource advisory councils—requirements. (a) Resource advisory councils... participation. (b) A resource advisory council advises the Bureau of Land Management official to whom it...

  7. 43 CFR 1784.6-1 - Resource advisory councils-requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Resource advisory councils-requirements... Advisory Committees § 1784.6-1 Resource advisory councils—requirements. (a) Resource advisory councils... participation. (b) A resource advisory council advises the Bureau of Land Management official to whom it...

  8. Dynamic load-sharing using predicted process resource requirements

    NASA Technical Reports Server (NTRS)

    Goswami, Kumar K.; Iyer, Ravishankar K.

    1990-01-01

    Heuristics which use predicted process resource requirements to make scheduling decisions are proposed. Four heuristics are presented. The first two, MINQ and SMPL, employ centralized scheduling and the remaining two, DMINQ and FDMINQ, use distributed scheduling. These heuristics are first compared against random scheduling and then against two conventional heuristics, CENTEX and DISTED, which schedule processes solely based on system state information. Results based on trace-driven simulations show that the proposed centralized heuristics offer significantly improved mean response time and they require fewer status update messages. In experiments using the same status update rates, SMPL response times were, on the average, 22 percent lower than those for CENTEX; MINQ response times were, on the average, 18 percent lower. The simulations also showed that MINQ and SMPL can perform as well as, or better than, CENTEX while using up to 70 percent fewer status update messages. The use of fewer status update messages imposes less overhead on the system. The use of prediction for distributed scheduling produced similar results. When prediction was used to filter small processes and execute them locally a 50 percent improvement in response times was obtained.

  9. Science requirements for free-flying imaging radar (FIREX) experiment for sea ice, renewable resources, nonrenewable resources and oceanography

    NASA Technical Reports Server (NTRS)

    Carsey, F.

    1982-01-01

    A future bilateral SAR program was studied. The requirements supporting a SAR mission posed by science and operations in sea-ice-covered waters, oceanography, renewable resources, and nonrenewable resources are addressed. The instrument, mission, and program parameters were discussed. Research investigations supporting a SAR flight and the subsequent overall mission requirements and tradeoffs are summarized.

  10. Resources

    MedlinePlus

    ... palate - resources Colon cancer - resources Cystic fibrosis - resources Depression - resources Diabetes - resources Digestive disease - resources Drug abuse - resources Eating disorders - resources Elder care - resources Epilepsy - resources Family troubles - ...

  11. A case study of exploiting enterprise resource planning requirements

    NASA Astrophysics Data System (ADS)

    Niu, Nan; Jin, Mingzhou; Cheng, Jing-Ru C.

    2011-05-01

    The requirements engineering (RE) processes have become a key to conceptualising corporate-wide integrated solutions based on packaged enterprise resource planning (ERP) software. The RE literature has mainly focused on procuring the most suitable ERP package. Little is known about how an organisation exploits the chosen ERP RE model to frame the business application development. This article reports an exploratory case study of a key tenet of ERP RE adoption, namely that aligning business applications to the packaged RE model leads to integral practices and economic development. The case study analysed a series interrelated pilot projects developed for a business division of a large IT manufacturing and service company, using Oracle's appl1ication implementation method (AIM). The study indicated that AIM RE improved team collaboration and project management experience, but needed to make hidden assumptions explicit to support data visibility and integrity. Our study can direct researchers towards rigorous empirical evaluations of ERP RE adoption, collect experiences and lessons learned for practitioners, and help generate more effective and mature processes when exploiting ERP RE methods.

  12. Water resource requirements of corn-based ethanol

    NASA Astrophysics Data System (ADS)

    Mubako, Stanley; Lant, Christopher

    2008-07-01

    Ethanol derived from fermentation of corn is a very water-intensive product with water to ethanol mass ratios of 927 to 1178 and volumetric ratios of 1174 to 1492 for the major rainfed corn-growing U.S. states of Illinois and Iowa and the leading irrigated corn-growing state of Nebraska, respectively. Over 99% of water requirements are for growing corn feed stocks, with 99% of that amount in Illinois and Iowa, occurring as evapotranspiration of rainfall in corn fields, and 60% as evapotranspiration of applied irrigation water in Nebraska. As a rough measure of water quality impacts, 65.5 g N, 23.8 g P, and 1.03 g of pesticides are applied, and 4.8 kg of soil is eroded per liter of ethanol produced. These results add to knowledge on corn-based ethanol's low net energy balance and high carbon footprint by demonstrating the high water resource intensity of corn-based ethanol production.

  13. 10 CFR 719.15 - What are the requirements for a staffing and resource plan?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false What are the requirements for a staffing and resource plan? 719.15 Section 719.15 Energy DEPARTMENT OF ENERGY CONTRACTOR LEGAL MANAGEMENT REQUIREMENTS Legal Management Plan § 719.15 What are the requirements for a staffing and resource plan? (a) For significant matters, the contractor must require...

  14. 48 CFR 873.109 - General requirements for acquisition of health-care resources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... acquisition of health-care resources. 873.109 Section 873.109 Federal Acquisition Regulations System... HEALTH-CARE RESOURCES 873.109 General requirements for acquisition of health-care resources. (a) Source... market research, including the determination that the acquisition involves health-care resources; (3)...

  15. 48 CFR 873.109 - General requirements for acquisition of health-care resources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... acquisition of health-care resources. 873.109 Section 873.109 Federal Acquisition Regulations System... HEALTH-CARE RESOURCES 873.109 General requirements for acquisition of health-care resources. (a) Source... market research, including the determination that the acquisition involves health-care resources; (3)...

  16. 48 CFR 873.109 - General requirements for acquisition of health-care resources.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... acquisition of health-care resources. 873.109 Section 873.109 Federal Acquisition Regulations System... HEALTH-CARE RESOURCES 873.109 General requirements for acquisition of health-care resources. (a) Source... market research, including the determination that the acquisition involves health-care resources; (3)...

  17. 30 CFR 280.25 - When may MMS require me to stop activities under this part?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When may MMS require me to stop activities under this part? 280.25 Section 280.25 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... resource; (2) You failed to comply with any applicable law, regulation, order or provision of the...

  18. 30 CFR 580.25 - When may BOEM require me to stop activities under this part?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false When may BOEM require me to stop activities under this part? 580.25 Section 580.25 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT... an archaeological resource; (2) You failed to comply with any applicable law, regulation, order...

  19. 30 CFR 580.25 - When may BOEM require me to stop activities under this part?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false When may BOEM require me to stop activities under this part? 580.25 Section 580.25 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT... an archaeological resource; (2) You failed to comply with any applicable law, regulation, order...

  20. 30 CFR 580.25 - When may BOEM require me to stop activities under this part?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false When may BOEM require me to stop activities under this part? 580.25 Section 580.25 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT... an archaeological resource; (2) You failed to comply with any applicable law, regulation, order...

  1. Indianapolis resource recovery facility; Community efforts and technology required for a successful project

    SciTech Connect

    Stevens, P.L. ); Henderson, J.S. ); Tulli, R. )

    1990-01-01

    There are many community needs. Refuse is an abundant byproduct of our civilization. The disposal of this byproduct has become a major problem for our cities. This paper describes on community's efforts to turn a community problem, refuse disposal, into a community asset. The paper describes the many aspects of effort and technology required to develop the Indianapolis Resource Recovery Facility. This facility required the cooperation of the public and private sectors to blend technology into a successful project. Special efforts were required to match appropriate technology to specific community needs and produce a successful and economically sound project. Five basic activities are presented. The first four activities are essential steps for any community to assure the right project fit to community needs. The areas presented are: defining community needs, technology evaluation (approaches evaluated), feasibility studies (economic studies), project implementation (bids and contracts), and a description of the Indianapolis resource recovery facility. A review of these five areas places a real world perspective on refuse as an alternative fuel and source of resource recovery.

  2. Survey of resource opportunities and critical evaluation of economic requirements

    NASA Technical Reports Server (NTRS)

    Clark, Benton C.

    1991-01-01

    A series of mission analyses were performed to evaluate human mission to Mars and the moon with and without the aid of planetary resource utilization. The types of trade studies that are considered include the use of resources to manufacture propellant, food, habitat atmospheric gases, and lander habitat structure. Also, the potential for export of resources from the moon, Mars, Phobos, Deimos, and selected asteroids is also examined. In all cases, mass leveraging is evaluated. For certain cases, economic factors are evaluated as well. It is concluded that some uses are highly leveraging on the mission, whereas others have lesser impact and, therefore, should be afforded lesser priority in resource utilization studies. This survey is made with a consistent set of scaling laws for spacecraft propulsion and habitation systems and subsystems, and therefore, provides a rational basis for comparing different resource locations and use strategies.

  3. Resources

    MedlinePlus

    ... Diabetes - resources Digestive disease - resources Drug abuse - resources Eating disorders - resources Elder care - resources Epilepsy - resources Family troubles - resources Gastrointestinal disorders - resources Hearing impairment - resources ...

  4. Resource requirements for a quality Doctor of Nursing Practice program.

    PubMed

    Frantz, Rita A

    2013-08-01

    Fundamental to planning, implementing, and sustaining a quality Doctor of Nursing Practice (DNP) program is access to the resources needed to foster a learning environment that prepares nurses for advanced practice and leadership in the future redesigned health care system. This creates formidable challenges for schools and colleges of nursing as they endeavor to address the nation's need for an increased supply of advanced practice nurses to provide access to high-quality, cost-effective care for an aging population. This article describes the essential resources needed to support the delivery of a DNP program and the proposed strategies needed to address the resource challenges. PMID:23855341

  5. PUBLIC PERCEPTIONS OF NATURAL RESOURCE DAMAGES AND THE RESOURCES THAT REQUIRE RESTORATION

    PubMed Central

    Burger, Joanna

    2014-01-01

    The public and health professionals are interested in restoring degraded ecosystem to provide goods and services. This study examined public perceptions in coastal New York and New Jersey about who is responsible for restoration of resources, which resources should be restored, by whom, and do they know the meaning of natural resource damage assessment (NRDA). More than 98% felt that resources should be restored; more (40%) thought the government should restore them, rather than the responsible party (23%). The highest rated resources were endangered wildlife, fish, mammals, and clams/crabs. Only 2% of respondents knew what NRDA meant. These data indicate that people felt strongly that resources should be restored and varied in who should restore them, suggesting that governmental agencies must clarify the relationship between chemical discharges, resource injury, NRDA, and restoration of those resources to produce clean air and water, fish and wildlife, and recreational opportunities. PMID:20711934

  6. Active Learning with Hands-On Resources.

    ERIC Educational Resources Information Center

    Crow, Tracy, Ed.

    1996-01-01

    The Eisenhower National Clearinghouse for Mathematics and Science Education (ENC) helps teachers by offering a broad assortment of services that enable them to quickly locate educational resources. This document is one in a series of print catalogs designed to give educators information about curriculum resources available for teaching math and…

  7. Precise Geodetic Infrastructure: National Requirements for a Shared Resource

    NASA Astrophysics Data System (ADS)

    Minster, J. H.; Altamimi, Z.; Blewitt, G.; Carter, W. E.; Cazenave, A. A.; Dragert, H.; Herring, T.; Larson, K. M.; Ries, J. C.; Sandwell, D. T.; Wahr, J. M.; Davis, J. L.; Feary, D. A.; Shanley, L. A.; Nrc Committee On The National RequirementsPrecision Geodetic Infrastructure

    2010-12-01

    Recognizing the growing reliance of a wide range of scientific and societal endeavors on infrastructure for precise geodesy, and recognizing geodetic infrastructure as a shared national resource, NASA, USNO, NGA (DoD), NSF, NGS (NOAA), and USGS requested the National Research Council (NRC) to provide an independent assessment of the benefits provided by geodetic observations and networks, as well as a plan for the future development and support of the infrastructure needed to meet the demand for increasingly greater precision. We recommend in this study that “The United States, to maintain leadership in industry and science, and as a matter of national security, should invest in maintaining and improving the geodetic infrastructure, through upgrades in network design and construction, modernization of current observing systems, deployment of improved multi-technique observing capabilities, and funding opportunities for research, analysis, and education in global geodesy.” Today’s precise global geodetic infrastructure is fragile, and we also recommend (1) an international cooperative effort to increase the density of the international geodetic network with a goal of reaching a network of at least 24 fundamental stations; (2) a national GNSS network constructed to scientific specifications, capable of streaming high-rate data in real-time, with no restrictions on data access; (3) continued support of international geodetic services; (4) a long-term commitment to maintain the International Terrestrial Reference Frame. The astonishing advances toward higher geodetic accuracy at increasing temporal resolution are made possible only by all components of the geodetic infrastructure working together as a coherent system. The components of the geodetic infrastructure, however, are dispersed among various departments, agencies, and organizations. The nation’s precise geodetic infrastructure has not been considered holistically before now. Nevertheless, it is a

  8. Ecosystem Matters: Activity and Resource Guide for Environmental Educators.

    ERIC Educational Resources Information Center

    Adams, Mary; And Others

    An ecological approach involved making conscious decisions which result in actions that responsibly contribute to the long-term stewardship of natural resources. This activity and resource guide was designed for use by both educators and resource managers to supplement existing courses and programs concerning ecological matters. These…

  9. 48 CFR 1352.239-72 - Security requirements for information technology resources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Clauses 1352.239-72 Security requirements for information technology resources. As prescribed in 48 CFR 1339.270(b), insert the following clause: Security Requirements for Information Technology Resources... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Security requirements...

  10. 48 CFR 1352.239-72 - Security requirements for information technology resources.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Clauses 1352.239-72 Security requirements for information technology resources. As prescribed in 48 CFR 1339.270(b), insert the following clause: Security Requirements for Information Technology Resources... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Security requirements...

  11. Water resources activities in Louisiana district, fiscal year 1985

    USGS Publications Warehouse

    Herbert, R.A.; Ellsworth, E.A.

    1985-01-01

    Water resources activities of the U.S. Geological Survey (USGS) in Louisiana consist of collecting water resources data and conducting interpretive hydrologic investigations and research. The water resources data and the results of the interpretive investigations are published or released by either the USGS or by cooperating agencies. The USGS water resources activities in Louisiana for the 1985 fiscal year (October 1, 1984 to September 30, 1985) are described, including data collection and dissemination, water resources appraisals (interpretive studies) and research. (Lantz-PTT)

  12. 78 FR 46597 - Agency Information Collection Activities: State Water Resources Research Institute Program Annual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-01

    ..., we published a Federal Register notice (78 FR 2422) announcing that we would submit this ICR to OMB....S. Geological Survey Agency Information Collection Activities: State Water Resources Research... Water Resources (NIWR) USGS Competitive Grant Program. As required by the Paperwork Reduction Act...

  13. Effects of resource activities upon repository siting and waste containment with reference to bedded salt

    SciTech Connect

    Ashby, J.; Rowe, J.

    1980-02-01

    The primary consideration for the suitability of a nuclear waste repository site is the overall ability of the repository to safely contain radioactive waste. This report is a discussion of the past, present, and future effects of resource activities on waste containment. Past and present resource activities which provide release pathways (i.e., leaky boreholes, adjacent mines) will receive initial evaluation during the early stages of any repository site study. However, other resource activities which may have subtle effects on containment (e.g., long-term pumping causing increased groundwater gradients, invasion of saline water causing lower retardation) and all potential future resource activities must also be considered during the site evaluation process. Resource activities will affect both the siting and the designing of repositories. Ideally, sites should be located in areas of low resource activity and low potential for future activity, and repository design should seek to eliminate or minimize the adverse effects of any resource activity. Buffer zones should be created to provide areas in which resource activities that might adversely affect containment can be restricted or curtailed. This could mean removing large areas of land from resource development. The impact of these frozen assets should be assessed in terms of their economic value and of their effect upon resource reserves. This step could require a major effort in data acquisition and analysis followed by extensive numerical modeling of regional fluid flow and mass transport. Numerical models should be used to assess the effects of resource activity upon containment and should include the cumulative effects of different resource activities. Analysis by other methods is probably not possible except for relatively simple cases.

  14. 30 CFR 280.30 - What activities will not require environmental analysis?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... THE OUTER CONTINENTAL SHELF Obligations Under This Part Environmental Issues § 280.30 What activities will not require environmental analysis? We anticipate that activities of the type listed below... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What activities will not require...

  15. Resource Requirements and Costs of Developing and Delivering MOOCs

    ERIC Educational Resources Information Center

    Hollands, Fiona M.; Tirthali, Devayani

    2014-01-01

    Given the ongoing alarm regarding uncontrollable costs of higher education, it would be reasonable to expect not only concern about the impact of MOOCs on educational outcomes, but also systematic efforts to document the resources expended on their development and delivery. However, there is little publicly available information on MOOC costs that…

  16. Human resource information systems: helping to meet Section 89 requirements.

    PubMed

    Spirig, J E

    1989-01-01

    After January 1, 1989, firms offering comprehensive benefits plans to employees must demonstrate that such plans do not discriminate against non-highly compensated workers. This article presents human resource information systems as a solution to Section 89 compliance problems and suggests integrating benefits and payroll information. PMID:10295776

  17. Earth resources requirements Skylab missions SL-1/SL-2, SL-3, and SL-4. Appendix B: Mission requirements

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Earth resources requirements to be investigated by Skylab missions 1 through 4 are presented tabularly. Areas to be investigated include: (1) agriculture, range, and forestry; (2) geology; (3) continental water resources; (4) ocean investigations; (5) atmospheric investigations; (6) coastal zones, shoals, and bays; (7) remote sensing techniques; and (8) cartography.

  18. Universe At Your Fingertips: An Astronomy Activity and Resource Notebook.

    ERIC Educational Resources Information Center

    Fraknoi, Andrew, Ed.

    The goal of this resource notebook is to provide activities selected by astronomers and classroom teachers, comprehensive resource lists and bibliographies, background material on astronomical topics, and teaching ideas from experienced astronomy educators. The activities are grouped into several major areas of study in astronomy: lunar phases and…

  19. 48 CFR 873.109 - General requirements for acquisition of health-care resources.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... acquisition of health-care resources. 873.109 Section 873.109 Federal Acquisition Regulations System... HEALTH-CARE RESOURCES 873.109 General requirements for acquisition of health-care resources. (a) Source selection authority. Contracting officers shall be the source selection authority for acquisitions of...

  20. 48 CFR 873.109 - General requirements for acquisition of health-care resources.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... acquisition of health-care resources. 873.109 Section 873.109 Federal Acquisition Regulations System... HEALTH-CARE RESOURCES 873.109 General requirements for acquisition of health-care resources. (a) Source selection authority. Contracting officers shall be the source selection authority for acquisitions of...

  1. 48 CFR 652.239-71 - Security Requirements for Unclassified Information Technology Resources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Unclassified Information Technology Resources. 652.239-71 Section 652.239-71 Federal Acquisition Regulations... Provisions and Clauses 652.239-71 Security Requirements for Unclassified Information Technology Resources. As... Technology Resources (SEP 2007) (a) General. The Contractor shall be responsible for information...

  2. 48 CFR 1252.239-70 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... unclassified information technology resources. 1252.239-70 Section 1252.239-70 Federal Acquisition Regulations... of Provisions and Clauses 1252.239-70 Security requirements for unclassified information technology resources. As prescribed in (TAR) 48 CFR 1239.70, insert the following clause: Security Requirements...

  3. Resources and Biological Activities of Natural Polyphenols

    PubMed Central

    Li, An-Na; Li, Sha; Zhang, Yu-Jie; Xu, Xiang-Rong; Chen, Yu-Ming; Li, Hua-Bin

    2014-01-01

    The oxidative stress imposed by reactive oxygen species (ROS) plays an important role in many chronic and degenerative diseases. As an important category of phytochemicals, phenolic compounds universally exist in plants, and have been considered to have high antioxidant ability and free radical scavenging capacity, with the mechanism of inhibiting the enzymes responsible for ROS production and reducing highly oxidized ROS. Therefore, phenolic compounds have attracted increasing attention as potential agents for preventing and treating many oxidative stress-related diseases, such as cardiovascular diseases, cancer, ageing, diabetes mellitus and neurodegenerative diseases. This review summarizes current knowledge of natural polyphenols, including resource, bioactivities, bioavailability and potential toxicity. PMID:25533011

  4. 30 CFR 280.30 - What activities will not require environmental analysis?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Obligations Under This Part Environmental Issues § 280.30 What activities will not require environmental... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What activities will not require environmental... environmental impact and will normally be categorically excluded from additional environmental analysis....

  5. 30 CFR 580.30 - What activities will not require environmental analysis?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Obligations Under This Part Environmental Issues § 580.30 What activities will not require environmental... 30 Mineral Resources 2 2013-07-01 2013-07-01 false What activities will not require environmental... environmental impact and will normally be categorically excluded from additional environmental analysis....

  6. 30 CFR 580.30 - What activities will not require environmental analysis?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Obligations Under This Part Environmental Issues § 580.30 What activities will not require environmental... 30 Mineral Resources 2 2012-07-01 2012-07-01 false What activities will not require environmental... environmental impact and will normally be categorically excluded from additional environmental analysis....

  7. 30 CFR 580.30 - What activities will not require environmental analysis?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Obligations Under This Part Environmental Issues § 580.30 What activities will not require environmental... 30 Mineral Resources 2 2014-07-01 2014-07-01 false What activities will not require environmental... environmental impact and will normally be categorically excluded from additional environmental analysis....

  8. 30 CFR 280.25 - When may BSEE require me to stop activities under this part?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false When may BSEE require me to stop activities... CONTINENTAL SHELF Obligations Under This Part Interrupted Activities § 280.25 When may BSEE require me to stop..., or immediate harm. This includes damage to life (including fish and other aquatic life),...

  9. 30 CFR 280.25 - When may BSEE require me to stop activities under this part?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false When may BSEE require me to stop activities... CONTINENTAL SHELF Obligations Under This Part Interrupted Activities § 280.25 When may BSEE require me to stop..., or immediate harm. This includes damage to life (including fish and other aquatic life),...

  10. 30 CFR 280.25 - When may BSEE require me to stop activities under this part?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false When may BSEE require me to stop activities... CONTINENTAL SHELF Obligations Under This Part Interrupted Activities § 280.25 When may BSEE require me to stop..., or immediate harm. This includes damage to life (including fish and other aquatic life),...

  11. Advanced extravehicular activity systems requirements definition study

    NASA Technical Reports Server (NTRS)

    1988-01-01

    A study to define the requirements for advanced extravehicular activities (AEVA) was conducted. The purpose of the study was to develop an understanding of the EVA technology requirements and to map a pathway from existing or developing technologies to an AEVA system capable of supporting long-duration missions on the lunar surface. The parameters of an AEVA system which must sustain the crewmembers and permit productive work for long periods in the lunar environment were examined. A design reference mission (DRM) was formulated and used as a tool to develop and analyze the EVA systems technology aspects. Many operational and infrastructure design issues which have a significant influence on the EVA system are identified.

  12. Groundwater: A Vital Resource. Student Activities.

    ERIC Educational Resources Information Center

    Taylor, Carla, Ed.

    Twenty-three activities dealing with various aspects of groundwater are provided in this manual. The activities are arranged under four headings: (1) the water cycle; (2) water distribution in soils (considering such topics as calculating water table depth and purifying water by filtering); (3) water quality (considering such topics as acid rain,…

  13. 30 CFR 280.25 - When may MMS require me to stop activities under this part?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false When may MMS require me to stop activities under this part? 280.25 Section 280.25 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE PROSPECTING FOR MINERALS OTHER THAN OIL, GAS, AND SULPHUR ON THE OUTER CONTINENTAL...

  14. 30 CFR 280.3 - What requirements must I follow when I conduct prospecting or research activities?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... research activities? You must conduct G&G prospecting activities or scientific research activities under... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What requirements must I follow when I conduct prospecting or research activities? 280.3 Section 280.3 Mineral Resources MINERALS MANAGEMENT...

  15. 30 CFR 580.3 - What requirements must I follow when I conduct prospecting or research activities?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... research activities? You must conduct G&G prospecting activities or scientific research activities under... 30 Mineral Resources 2 2013-07-01 2013-07-01 false What requirements must I follow when I conduct prospecting or research activities? 580.3 Section 580.3 Mineral Resources BUREAU OF OCEAN ENERGY...

  16. 30 CFR 580.3 - What requirements must I follow when I conduct prospecting or research activities?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... research activities? You must conduct G&G prospecting activities or scientific research activities under... 30 Mineral Resources 2 2012-07-01 2012-07-01 false What requirements must I follow when I conduct prospecting or research activities? 580.3 Section 580.3 Mineral Resources BUREAU OF OCEAN ENERGY...

  17. 30 CFR 580.3 - What requirements must I follow when I conduct prospecting or research activities?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... research activities? You must conduct G&G prospecting activities or scientific research activities under... 30 Mineral Resources 2 2014-07-01 2014-07-01 false What requirements must I follow when I conduct prospecting or research activities? 580.3 Section 580.3 Mineral Resources BUREAU OF OCEAN ENERGY...

  18. Mitochondrial fragmentation in excitotoxicity requires ROCK activation.

    PubMed

    Martorell-Riera, Alejandro; Segarra-Mondejar, Marc; Reina, Manuel; Martínez-Estrada, Ofelia M; Soriano, Francesc X

    2015-01-01

    Mitochondria morphology constantly changes through fission and fusion processes that regulate mitochondrial function, and it therefore plays a prominent role in cellular homeostasis. Cell death progression is associated with mitochondrial fission. Fission is mediated by the mainly cytoplasmic Drp1, which is activated by different post-translational modifications and recruited to mitochondria to perform its function. Our research and other studies have shown that in the early moments of excitotoxic insult Drp1 must be nitrosylated to mediate mitochondrial fragmentation in neurons. Nonetheless, mitochondrial fission is a multistep process in which filamentous actin assembly/disassembly and myosin-mediated mitochondrial constriction play prominent roles. Here we establish that in addition to nitric oxide production, excitotoxicity-induced mitochondrial fragmentation also requires activation of the actomyosin regulator ROCK. Although ROCK1 has been shown to phosphorylate and activate Drp1, experiments using phosphor-mutant forms of Drp1 in primary cortical neurons indicate that in excitotoxic conditions, ROCK does not act directly on Drp1 to mediate fission, but may act on the actomyosin complex. Thus, these data indicate that a wider range of signaling pathways than those that target Drp1 are amenable to be inhibited to prevent mitochondrial fragmentation as therapeutic option. PMID:25789413

  19. 48 CFR 352.239-72 - Security requirements for Federal information technology resources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Security requirements for... Provisions and Clauses 352.239-72 Security requirements for Federal information technology resources. As prescribed in 339.7103, the Contracting Officer shall insert the following clause: Security Requirements...

  20. 48 CFR 352.239-72 - Security requirements for Federal information technology resources.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Security requirements for... Provisions and Clauses 352.239-72 Security requirements for Federal information technology resources. As prescribed in 339.7103, the Contracting Officer shall insert the following clause: Security Requirements...

  1. 48 CFR 652.239-71 - Security Requirements for Unclassified Information Technology Resources.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Security Requirements for... Provisions and Clauses 652.239-71 Security Requirements for Unclassified Information Technology Resources. As prescribed in 639.107-70(b), insert the following clause: Security Requirements for Unclassified...

  2. 48 CFR 652.239-71 - Security Requirements for Unclassified Information Technology Resources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Security Requirements for... Provisions and Clauses 652.239-71 Security Requirements for Unclassified Information Technology Resources. As prescribed in 639.107-70(b), insert the following clause: Security Requirements for Unclassified...

  3. 48 CFR 552.239-71 - Security Requirements for Unclassified Information Technology Resources.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Security Requirements for... Text of Provisions and Clauses 552.239-71 Security Requirements for Unclassified Information Technology Resources. As prescribed in 539.7002(b), insert the following clause: Security Requirements for...

  4. 48 CFR 652.239-71 - Security Requirements for Unclassified Information Technology Resources.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Security Requirements for... Provisions and Clauses 652.239-71 Security Requirements for Unclassified Information Technology Resources. As prescribed in 639.107-70(b), insert the following clause: Security Requirements for Unclassified...

  5. 48 CFR 552.239-71 - Security Requirements for Unclassified Information Technology Resources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Security Requirements for... Text of Provisions and Clauses 552.239-71 Security Requirements for Unclassified Information Technology Resources. As prescribed in 539.7002(b), insert the following clause: Security Requirements for...

  6. 48 CFR 352.239-72 - Security requirements for Federal information technology resources.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Security requirements for... Provisions and Clauses 352.239-72 Security requirements for Federal information technology resources. As prescribed in 339.7103, the Contracting Officer shall insert the following clause: Security Requirements...

  7. 48 CFR 1252.239-70 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... of Provisions and Clauses 1252.239-70 Security requirements for unclassified information technology resources. As prescribed in (TAR) 48 CFR 1239.70, insert the following clause: Security Requirements for... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Security requirements...

  8. 48 CFR 552.239-71 - Security Requirements for Unclassified Information Technology Resources.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Security Requirements for... Text of Provisions and Clauses 552.239-71 Security Requirements for Unclassified Information Technology Resources. As prescribed in 539.7002(b), insert the following clause: Security Requirements for...

  9. 25 CFR 161.200 - Is an Indian agricultural resource management plan required?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Is an Indian agricultural resource management plan... WATER NAVAJO PARTITIONED LANDS GRAZING PERMITS General Provisions § 161.200 Is an Indian agricultural resource management plan required? (a) Yes, Navajo Partitioned Lands must be managed in accordance with...

  10. 25 CFR 166.311 - Is an Indian agricultural resource management plan required?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Is an Indian agricultural resource management plan... WATER GRAZING PERMITS Land and Operations Management Management Plans and Environmental Compliance § 166.311 Is an Indian agricultural resource management plan required? (a) Indian agricultural land...

  11. Satellite Power System (SPS) resource requirements (critical materials, energy and land)

    NASA Technical Reports Server (NTRS)

    Kotin, A. D.

    1978-01-01

    The resource impacts of the proposed satellite power system are evaluated. Three classes of resource impacts are considered separately: critical materials, energy, and land use. The analysis focuses on the requirements associated with the annual development of two five-gigawatt satellites and the associated receiving facilities.

  12. Scaling Up Child and Adolescent Mental Health Services in South Africa: Human Resource Requirements and Costs

    ERIC Educational Resources Information Center

    Lund, Crick; Boyce, Gerard; Flisher, Alan J.; Kafaar, Zuhayr; Dawes, Andrew

    2009-01-01

    Background: Children and adolescents with mental health problems have poor service cover in low- and middle-income countries. Little is known about the resources that would be required to provide child and adolescent mental health services (CAMHS) in these countries. The purpose of this study was to calculate the human resources and associated…

  13. 48 CFR 3052.204-70 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... for unclassified information technology resources. As prescribed in (HSAR) 48 CFR 3004.470-3, insert a clause substantially the same as follows: Security Requirements for Unclassified Information Technology... unclassified information technology resources. 3052.204-70 Section 3052.204-70 Federal Acquisition...

  14. 43 CFR 1784.6-1 - Resource advisory councils-requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Resource advisory councils-requirements. 1784.6-1 Section 1784.6-1 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR GENERAL MANAGEMENT (1000) COOPERATIVE RELATIONS Advisory Committees § 1784.6-1 Resource...

  15. A Pilot Test of the Resource Requirements Prediction Model at Humboldt State College.

    ERIC Educational Resources Information Center

    California State Colleges, Inglewood. Office of the Chancellor.

    This publication presents Humboldt State College's experience with the pilot testing of the Resource Requirements Prediction Model (RRPM), an analytic computer designed to aid management decisionmaking and planning in institutions of higher education. RRPM has great potential as a planning tool that can improve resource management in higher…

  16. 42 CFR 436.843 - Medically needy resource standard: State plan requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Medically needy resource standard: State plan... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN GUAM, PUERTO RICO, AND THE VIRGIN ISLANDS Financial Requirements for the Medically Needy Medically Needy Resource...

  17. 42 CFR 435.843 - Medically needy resource standard: State plan requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Medically needy resource standard: State plan... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN THE STATES, DISTRICT OF... Financial Requirements for the Medically Needy Medically Needy Resource Standard § 435.843 Medically...

  18. 42 CFR 435.840 - Medically needy resource standard: General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Medically needy resource standard: General... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN THE STATES, DISTRICT OF... Financial Requirements for the Medically Needy Medically Needy Resource Standard § 435.840 Medically...

  19. 42 CFR 436.840 - Medically needy resource standard: General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Medically needy resource standard: General... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN GUAM, PUERTO RICO, AND THE VIRGIN ISLANDS Financial Requirements for the Medically Needy Medically Needy Resource...

  20. 78 FR 18562 - Economic and Environmental Principles and Requirements for Water and Related Land Resources...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-27

    ... QUALITY Economic and Environmental Principles and Requirements for Water and Related Land Resources Implementation Studies; Final AGENCY: Council on Environmental Quality. ACTION: Notice of Availability of Final... Quality at (202) 395-5750. SUPPLEMENTARY INFORMATION: Section 2031 of the Water Resources Development...

  1. 42 CFR 435.840 - Medically needy resource standard: General requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Medically needy resource standard: General... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN THE STATES, DISTRICT OF... Financial Requirements for the Medically Needy Medically Needy Resource Standard § 435.840 Medically...

  2. 42 CFR 436.840 - Medically needy resource standard: General requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Medically needy resource standard: General... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN GUAM, PUERTO RICO, AND THE VIRGIN ISLANDS Financial Requirements for the Medically Needy Medically Needy Resource...

  3. 42 CFR 436.840 - Medically needy resource standard: General requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Medically needy resource standard: General... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN GUAM, PUERTO RICO, AND THE VIRGIN ISLANDS Financial Requirements for the Medically Needy Medically Needy Resource...

  4. 42 CFR 436.843 - Medically needy resource standard: State plan requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Medically needy resource standard: State plan... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN GUAM, PUERTO RICO, AND THE VIRGIN ISLANDS Financial Requirements for the Medically Needy Medically Needy Resource...

  5. 42 CFR 436.843 - Medically needy resource standard: State plan requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Medically needy resource standard: State plan... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN GUAM, PUERTO RICO, AND THE VIRGIN ISLANDS Financial Requirements for the Medically Needy Medically Needy Resource...

  6. 42 CFR 436.843 - Medically needy resource standard: State plan requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Medically needy resource standard: State plan... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN GUAM, PUERTO RICO, AND THE VIRGIN ISLANDS Financial Requirements for the Medically Needy Medically Needy Resource...

  7. 42 CFR 435.843 - Medically needy resource standard: State plan requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Medically needy resource standard: State plan... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN THE STATES, DISTRICT OF... Financial Requirements for the Medically Needy Medically Needy Resource Standard § 435.843 Medically...

  8. 42 CFR 435.840 - Medically needy resource standard: General requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Medically needy resource standard: General... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN THE STATES, DISTRICT OF... Financial Requirements for the Medically Needy Medically Needy Resource Standard § 435.840 Medically...

  9. 42 CFR 435.840 - Medically needy resource standard: General requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Medically needy resource standard: General... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN THE STATES, DISTRICT OF... Financial Requirements for the Medically Needy Medically Needy Resource Standard § 435.840 Medically...

  10. 42 CFR 436.840 - Medically needy resource standard: General requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Medically needy resource standard: General... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN GUAM, PUERTO RICO, AND THE VIRGIN ISLANDS Financial Requirements for the Medically Needy Medically Needy Resource...

  11. 42 CFR 436.840 - Medically needy resource standard: General requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Medically needy resource standard: General... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN GUAM, PUERTO RICO, AND THE VIRGIN ISLANDS Financial Requirements for the Medically Needy Medically Needy Resource...

  12. 42 CFR 435.843 - Medically needy resource standard: State plan requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Medically needy resource standard: State plan... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN THE STATES, DISTRICT OF... Financial Requirements for the Medically Needy Medically Needy Resource Standard § 435.843 Medically...

  13. 42 CFR 435.840 - Medically needy resource standard: General requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Medically needy resource standard: General... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN THE STATES, DISTRICT OF... Financial Requirements for the Medically Needy Medically Needy Resource Standard § 435.840 Medically...

  14. 42 CFR 435.843 - Medically needy resource standard: State plan requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Medically needy resource standard: State plan... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN THE STATES, DISTRICT OF... Financial Requirements for the Medically Needy Medically Needy Resource Standard § 435.843 Medically...

  15. 42 CFR 436.843 - Medically needy resource standard: State plan requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Medically needy resource standard: State plan... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN GUAM, PUERTO RICO, AND THE VIRGIN ISLANDS Financial Requirements for the Medically Needy Medically Needy Resource...

  16. 42 CFR 435.843 - Medically needy resource standard: State plan requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Medically needy resource standard: State plan... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN THE STATES, DISTRICT OF... Financial Requirements for the Medically Needy Medically Needy Resource Standard § 435.843 Medically...

  17. Structural requirements of bitter taste receptor activation

    PubMed Central

    Brockhoff, Anne; Behrens, Maik; Niv, Masha Y.; Meyerhof, Wolfgang

    2010-01-01

    An important question in taste research is how 25 receptors of the human TAS2R family detect thousands of structurally diverse compounds. An answer to this question may arise from the observation that TAS2Rs in general are broadly tuned to interact with numerous substances. Ultimately, interaction with chemically diverse agonists requires architectures of binding pockets tailored to combine flexibility with selectivity. The present study determines the structure of hTAS2R binding pockets. We focused on a subfamily of closely related hTAS2Rs exhibiting pronounced amino acid sequence identities but unique agonist activation spectra. The generation of chimeric and mutant receptors followed by calcium imaging analyses identified receptor regions and amino acid residues critical for activation of hTAS2R46, -R43, and -R31. We found that the carboxyl-terminal regions of the investigated receptors are crucial for agonist selectivity. Intriguingly, exchanging two residues located in transmembrane domain seven between hTAS2R46, activated by strychnine, and hTAS2R31, activated by aristolochic acid, was sufficient to invert agonist selectivity. Further mutagenesis revealed additional positions involved in agonist interaction. The transfer of functionally relevant amino acids identified in hTAS2R46 to the corresponding positions of hTAS2R43 and -R31 resulted in pharmacological properties indistinguishable from the parental hTAS2R46. In silico modeling of hTAS2R46 allowed us to visualize the putative mode of interaction between agonists and hTAS2Rs. Detailed structure-function analyses of hTAS2Rs may ultimately pave the way for the development of specific antagonists urgently needed for more sophisticated analyses of human bitter taste perception. PMID:20534469

  18. Piezoelectric Power Requirements for Active Vibration Control

    NASA Technical Reports Server (NTRS)

    Brennan, Matthew C.; McGowan, Anna-Maria Rivas

    1997-01-01

    This paper presents a method for predicting the power consumption of piezoelectric actuators utilized for active vibration control. Analytical developments and experimental tests show that the maximum power required to control a structure using surface-bonded piezoelectric actuators is independent of the dynamics between the piezoelectric actuator and the host structure. The results demonstrate that for a perfectly-controlled system, the power consumption is a function of the quantity and type of piezoelectric actuators and the voltage and frequency of the control law output signal. Furthermore, as control effectiveness decreases, the power consumption of the piezoelectric actuators decreases. In addition, experimental results revealed a non-linear behavior in the material properties of piezoelectric actuators. The material non- linearity displayed a significant increase in capacitance with an increase in excitation voltage. Tests show that if the non-linearity of the capacitance was accounted for, a conservative estimate of the power can easily be determined.

  19. Preface: Terrestrial Fieldwork to Support in situ Resource Utilization (ISRU) and Robotic Resource Prospecting for Future Activities in Space

    NASA Astrophysics Data System (ADS)

    Sanders, Gerald B.

    2015-05-01

    Finding, extracting, and using resources at the site of robotic and human exploration activities holds the promise of enabling sustainable and affordable exploration of the Moon, Mars, and asteroids, and eventually allow humans to expand their economy and habitation beyond the surface of the Earth. Commonly referred to as in situ Resource Utilization (ISRU), mineral and volatile resources found in space can be converted into oxygen, water, metals, fuels, and manufacturing and construction materials (such as plastics and concrete) for transportation, power, life support, habitation construction, and part/logistics manufacturing applications. For every kilogram of payload landed on the surface of the Moon or Mars, 7.5-11 kg of payload (mostly propellant) needs to be launched into low Earth orbit. Therefore, besides promising long-term self-sufficiency and infrastructure growth, ISRU can provide significant reductions in launch costs and the number of launches required. Key to being able to use space resources is knowing where they are located, how much is there, and how the resources are distributed. While ISRU holds great promise, it has also never been demonstrated in an actual space mission. Therefore, operations and hardware associated with each ISRU prospecting, excavation, transportation, and processing step must be examined, tested, and finally integrated to enable the end goal of using space resources in future human space missions.

  20. Some Astronomy 101 Activities Using Internet Resources

    NASA Astrophysics Data System (ADS)

    West, M. L.

    2000-12-01

    Reputable Internet sites provide a wealth of visual, textual, and numerical data for student activities, as well as some fun simulations. Three activities will be described which have been used in Astronomy 101 classes for non-science students. An exercise in model making and problem solving uses the Astronomy Workshop (janus.astro.umd.edu/astro/impact.html) of the University of Maryland. This site provides a quick simulation of an impact with a planet. One can choose the target, the projectile composition (icy, rocky, or iron), the projectile's diameter, and the projectile's speed. The output provides the energy of impact, the earthquake magnitude, the crater's diameter and depth, and the frequency of such impacts. Students run simulations, pool their data, then collaborate to try to figure out the numerical model behind the simulations. They make predictions, test them, and learn that graphing and physical insight are both important tools. Extrasolar planets are now numerous and fascinating. Students use data from Geoff Marcy's group (www.exoplanets.org) to calculate the masses of the planets using a spreadsheet. They discover that the masses of the stars must depend on spectral type. Correlations among parameters are investigated graphically. As a preparation for writing term papers students review and critique selected sites (csam.montclair.edu/ west/ideasresources.html, west/astrolnk.html), discuss them in small groups, then present the "best" sites to the whole class. Teamwork, evaluation, critical thinking, and public speaking skills are emphasized in this class session. The students find these collaborative activities to be exciting, challenging, and enjoyable as well as increasing their science literacy and problem solving skills.

  1. Structural Requirements for CNS Active Opioid Glycopeptides.

    PubMed

    Lefever, Mark; Li, Yingxue; Anglin, Bobbi; Muthu, Dhanasekaran; Giuvelis, Denise; Lowery, John J; Knapp, Brian I; Bidlack, Jean M; Bilsky, Edward J; Polt, Robin

    2015-08-13

    Glycopeptides related to β-endorphin penetrate the blood-brain barrier (BBB) of mice to produce antinociception. Two series of glycopeptides were assessed for opioid receptor binding affinity. Attempts to alter the mu-selectivity of [D-Ala(2),N-MePhe(4),Gly-ol(5)]enkephalin (DAMGO)-related glycopeptides by altering the charged residues of the amphipathic helical address were unsuccessful. A series of pan-agonists was evaluated for antinociceptive activity (55 °C tail flick) in mice. A flexible linker was required to maintain antinociceptive activity. Circular dichroism (CD) in H2O, trifluoroethanol (TFE), and SDS micelles confirmed the importance of the amphipathic helices (11s → 11sG → 11) for antinociception. The glycosylated analogues showed only nascent helices and random coil conformations in H2O. Chemical shift indices (CSI) and nuclear Overhauser effects (NOE) with 600 MHz NMR and CD confirmed helical structures in micelles, which were rationalized by molecular dynamics calculations. Antinociceptive studies with mice confirm that these glycosylated endorphin analogues are potential drug candidates that penetrate the BBB to produce potent central effects. PMID:26125201

  2. 30 CFR 285.634 - What activities require a revision to my COP, and when will MMS approve the revision?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What activities require a revision to my COP... OUTER CONTINENTAL SHELF Plans and Information Requirements Activities Under An Approved Cop § 285.634 What activities require a revision to my COP, and when will MMS approve the revision? (a) You...

  3. 30 CFR 585.617 - What activities require a revision to my SAP, and when will BOEM approve the revision?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false What activities require a revision to my SAP... FACILITIES ON THE OUTER CONTINENTAL SHELF Plans and Information Requirements Activities Under An Approved Sap § 585.617 What activities require a revision to my SAP, and when will BOEM approve the revision? (a)...

  4. 30 CFR 585.617 - What activities require a revision to my SAP, and when will BOEM approve the revision?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false What activities require a revision to my SAP... FACILITIES ON THE OUTER CONTINENTAL SHELF Plans and Information Requirements Activities Under An Approved Sap § 585.617 What activities require a revision to my SAP, and when will BOEM approve the revision? (a)...

  5. 30 CFR 285.617 - What activities require a revision to my SAP, and when will MMS approve the revision?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What activities require a revision to my SAP... OUTER CONTINENTAL SHELF Plans and Information Requirements Activities Under An Approved Sap § 285.617 What activities require a revision to my SAP, and when will MMS approve the revision? (a) You...

  6. 30 CFR 585.617 - What activities require a revision to my SAP, and when will BOEM approve the revision?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false What activities require a revision to my SAP... FACILITIES ON THE OUTER CONTINENTAL SHELF Plans and Information Requirements Activities Under An Approved Sap § 585.617 What activities require a revision to my SAP, and when will BOEM approve the revision? (a)...

  7. The Development of a Resource for Physically Active School Settings

    ERIC Educational Resources Information Center

    Bradley, Vicki R.; O'Connor, Justen P.

    2009-01-01

    This project describes the development of a resource designed to facilitate the exploration of factors influencing physical activity within school settings across multiple levels. Using a socio-ecological framework, the study draws upon factors across three domains that potentially impact physical activity levels within school settings: The…

  8. WATER: Water Activities Teaching Environmental Responsibility: Teacher Resource, Environmental Science.

    ERIC Educational Resources Information Center

    Kramer, Ed, Ed.; And Others

    This activity book was developed as part of an effort to protect water quality of the Stillwater River, Ohio, through a Watershed Protection Project. It is designed to raise teachers' and students' awareness and trigger a sense of stewardship towards the preservation of water resources. The activities are generally appropriate for elementary age…

  9. Dramatic Activities in Language Arts Classrooms: Resource Summary. ERIC Digest.

    ERIC Educational Resources Information Center

    Tatar, Sibel

    This digest reviews some of the related literature about the benefits of classroom drama activities and introduces a variety of resources to help educators incorporate dramatic activities in their language arts classrooms. The digest notes that although several terms have been used to refer to "classroom drama" such as creative dramatics,…

  10. Education & Recycling: Educator's Waste Management Resource and Activity Guide 1994.

    ERIC Educational Resources Information Center

    California State Dept. of Conservation. Sacramento. Div. of Recycling.

    This activity guide for grades K-12 reinforces the concepts of recycling, reducing, and reusing through a series of youth-oriented activities. The guide incorporates a video-based activity, multiple session classroom activities, and activities requiring group participation and student conducted research. Constructivist learning theory was…

  11. Earth resources-regional transfer activity contracts review

    NASA Technical Reports Server (NTRS)

    Bensko, J., Jr.; Daniels, J. L.; Downs, S. W., Jr.; Jones, N. L.; Morton, R. R.; Paludan, C. T.

    1977-01-01

    A regional transfer activity contracts review held by the Earth Resources Office was summarized. Contracts in the earth resources field primarily directed toward applications of satellite data and technology in solution of state and regional problems were reviewed. A summary of the progress of each contract was given in order to share experiences of researchers across a seven state region. The region included Missouri, Kentucky, Tennessee, Mississippi, Alabama, Georgia, and North Carolina. Research in several earth science disciplines included forestry, limnology, water resources, land use, geology, and mathematical modeling. The use of computers for establishment of information retrieval systems was also emphasized.

  12. Natural resource management activities at the Savannah River Site. Environmental Assessment

    SciTech Connect

    Not Available

    1993-07-01

    This environmental assessment (EA) reviews the environmental consequences of ongoing natural resource management activities on the Savannah River Site (SRS). Appendix A contains the Natural Resources Management Plant (NRMP). While several SRS organizations have primary responsibilities for different elements of the plan, the United States Department of Agriculture (USDA), Forest Service, Savannah River Forest Station (SRFS) is responsible for most elements. Of the river scenarios defined in 1985, the High-Intensity Management alternative established the upper bound of environmental consequences; it represents a more intense level of resource management than that being performed under current resource management activities. This alternative established compliance mechanisms for several natural resource-related requirements and maximum practical timber harvesting. Similarly, the Low-Intensity Management alternative established the lower bound of environmental consequences and represents a less intense level of resource management than that being performed under current resource management activities. This alternative also established compliance mechanisms, but defined a passively managed natural area. The Proposed Action of this EA describes the current level of multiple-natural resource management. This EA reviews the proposed action, and the high and low intensity alternative scenarios.

  13. Integrating natural resource damage assessment and environmental restoration activities at DOE facilities

    SciTech Connect

    1993-10-01

    Environmental restoration activities are currently under way at many U.S. Department of Energy (DOE) sites under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended. DOE is the CERCLA lead response agency for these activities. Section 120 of CERCLA also could subject DOE to liability for natural resource damages resulting from hazardous substance releases at its sites. A Natural Resource Damage Assessment (NRDA) process is used to determine whether natural resources have been injured and to calculate compensatory monetary damages to be used to restore the natural resources. In addition to restoration costs, damages may include costs of conducting the damage assessment and compensation for interim losses of natural resource services that occur before resource restoration is complete. Natural resource damages represent a potentially significant source of additional monetary claims under CERCLA, but are not well known or understood by many DOE staff and contractors involved in environmental restoration activities. This report describes the requirements and procedures of NRDA in order to make DOE managers aware of what the process is designed to do. It also explains how to integrate the NRDA and CERCLA Remedial Investigation/Feasibility Study processes, showing how the technical and cost analysis concepts of NRDA can be borrowed at strategic points in the CERCLA process to improve decisionmaking and more quickly restore natural resource services at the lowest total cost to the public.

  14. Integrating Natural Resource Damage Assessment and environmental restoration activities at DOE facilities

    SciTech Connect

    Not Available

    1993-10-01

    Environmental restoration activities are currently under way at many US Department of Energy (DOE) sites under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). DOE is the CERCLA lead response agency for these activities. Section 120 of CERCLA also could subject DOE to liability for natural resource damages resulting from hazardous substance releases at its sites. A Natural Resource Damage Assessment (NRDA) process is used to determine whether natural resources have been injured and to calculate compensatory monetary damages to be used to restore the natural resources. In addition to restoration costs, damages may include costs of conducting the damage assessment and compensation for interim losses of natural resource services that occur before resource restoration is complete. Natural resource damages represent a potentially significant source of additional monetary claims under CERCLA, but are not well known or understood by many DOE staff and contractors involved in environmental restoration activities. This report describes the requirements and procedures of NRDA in order to make DOE managers aware of what the process is designed to do. It also explains how to integrate the NRDA and CERCLA Remedial Investigation/Feasibility Study processes, showing how the technical and cost analysis concepts of NRDA can be borrowed at strategic points in the CERCLA process to improve decisionmaking and more quickly restore natural resource services at the lowest total cost to the public.

  15. 30 CFR 285.634 - What activities require a revision to my COP, and when will MMS approve the revision?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What activities require a revision to my COP... Activities Under An Approved Cop § 285.634 What activities require a revision to my COP, and when will MMS... your approved COP, describing in detail the type of activities you propose to conduct. We...

  16. 30 CFR 285.617 - What activities require a revision to my SAP, and when will MMS approve the revision?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What activities require a revision to my SAP... Activities Under An Approved Sap § 285.617 What activities require a revision to my SAP, and when will MMS... your approved SAP, describing in detail the type of activities you propose to conduct. We...

  17. 48 CFR 1252.239-70 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... resources. As prescribed in (TAR) 48 CFR 1239.70, insert the following clause: Security Requirements for... security requirements in accordance with Federal and DOT policies and procedures, as they may be amended... Information Technology security for all systems connected to a Department of Transportation (DOT) network...

  18. 48 CFR 1804.470 - Security requirements for unclassified information technology (IT) resources.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Security requirements for unclassified information technology (IT) resources. 1804.470 Section 1804.470 Federal Acquisition Regulations... Classified Information Within Industry 1804.470 Security requirements for unclassified information...

  19. 48 CFR 1804.470 - Security requirements for unclassified information technology (IT) resources.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Security requirements for unclassified information technology (IT) resources. 1804.470 Section 1804.470 Federal Acquisition Regulations... Classified Information Within Industry 1804.470 Security requirements for unclassified information...

  20. 48 CFR 1804.470 - Security requirements for unclassified information technology (IT) resources.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Security requirements for unclassified information technology (IT) resources. 1804.470 Section 1804.470 Federal Acquisition Regulations... Classified Information Within Industry 1804.470 Security requirements for unclassified information...

  1. 48 CFR 1804.470 - Security requirements for unclassified information technology (IT) resources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Security requirements for unclassified information technology (IT) resources. 1804.470 Section 1804.470 Federal Acquisition Regulations... Classified Information Within Industry 1804.470 Security requirements for unclassified information...

  2. 48 CFR 1852.204-76 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Security requirements for... CONTRACT CLAUSES Texts of Provisions and Clauses 1852.204-76 Security requirements for unclassified information technology resources. As prescribed in 1804.470-4(a), insert the following clause:...

  3. 48 CFR 1852.204-76 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Security requirements for... CONTRACT CLAUSES Texts of Provisions and Clauses 1852.204-76 Security requirements for unclassified information technology resources. As prescribed in 1804.470-4(a), insert the following clause:...

  4. 48 CFR 1852.204-76 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Security requirements for... CONTRACT CLAUSES Texts of Provisions and Clauses 1852.204-76 Security requirements for unclassified information technology resources. As prescribed in 1804.470-4(a), insert the following clause:...

  5. 32 CFR Enclosure 2 - Requirements for Environmental Considerations-Foreign Nations and Protected Global Resources

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Requirements for Environmental Considerations-Foreign Nations and Protected Global Resources 2 Enclosure 2 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE ENVIRONMENT ENVIRONMENTAL EFFECTS ABROAD OF MAJOR DEPARTMENT OF DEFENSE ACTIONS Information requirements. Pt....

  6. 32 CFR Enclosure 2 - Requirements for Environmental Considerations-Foreign Nations and Protected Global Resources

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Requirements for Environmental Considerations-Foreign Nations and Protected Global Resources 2 Enclosure 2 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE ENVIRONMENT ENVIRONMENTAL EFFECTS ABROAD OF MAJOR DEPARTMENT OF DEFENSE ACTIONS Information requirements. Pt....

  7. 14 CFR 1274.937 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Security requirements for unclassified... Conditions § 1274.937 Security requirements for unclassified information technology resources. Security... for Information Technology security for all systems connected to a NASA network or operated by...

  8. 14 CFR 1274.937 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Security requirements for unclassified... Conditions § 1274.937 Security requirements for unclassified information technology resources. Security... for Information Technology security for all systems connected to a NASA network or operated by...

  9. 48 CFR 1852.204-76 - Security requirements for unclassified information technolocgy resources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Security requirements for... CONTRACT CLAUSES Texts of Provisions and Clauses 1852.204-76 Security requirements for unclassified information technolocgy resources. As prescribed in 1804.470-4(a), insert the following clause:...

  10. 48 CFR 352.239-72 - Security requirements for Federal information technology resources.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the HHS Office of the Chief Information Officer's (OCIO) Web site. (c) Contractor security... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Security requirements for... Provisions and Clauses 352.239-72 Security requirements for Federal information technology resources....

  11. 48 CFR 352.239-72 - Security requirements for Federal information technology resources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the HHS Office of the Chief Information Officer's (OCIO) Web site. (c) Contractor security... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Security requirements for... Provisions and Clauses 352.239-72 Security requirements for Federal information technology resources....

  12. 48 CFR 1804.470 - Security requirements for unclassified information technology (IT) resources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Security requirements for unclassified information technology (IT) resources. 1804.470 Section 1804.470 Federal Acquisition Regulations... Classified Information Within Industry 1804.470 Security requirements for unclassified information...

  13. Analyzing learning during Peer Instruction dialogues: A resource activation framework

    NASA Astrophysics Data System (ADS)

    Wood, Anna K.; Galloway, Ross K.; Hardy, Judy; Sinclair, Christine M.

    2014-12-01

    Peer Instruction (PI) is an evidence based pedagogy commonly used in undergraduate physics instruction. When asked questions designed to test conceptual understanding, it has been observed that the proportion of students choosing the correct answer increases following peer discussion; however, relatively little is known about what takes place during these discussions or how they are beneficial to the processes of learning physics [M. C. James and S. Willoughby, Am. J. Phys. 79, 123 (2011)]. In this paper a framework for analyzing PI discussions developed through the lens of the "resources model" [D. Hammer, Am. J. Phys. 64, 1316 (1996); D. Hammer et al., Information Age Publishing (2005)] is proposed. A central hypothesis for this framework is that the dialogue with peers plays a crucial role in activating appropriate cognitive resources, enabling the students to see the problem differently, and therefore to answer the questions correctly. This framework is used to gain greater insights into the PI discussions of first year undergraduate physics students at the University of Edinburgh, UK, which were recorded using Livescribe Smartpens. Analysis of the dialogues revealed three different types of resource activation corresponding to increasing cognitive grain size. These were activation of knowledge elements, activation of linkages between knowledge elements, and activation of control structures (epistemic games and epistemological frames). Three case studies are examined to illustrate the role that peer dialogue plays in the activation of these cognitive resources in a PI session. The implications for pedagogical practice are discussed.

  14. Current water resources activities in Arkansas, 1984-85

    USGS Publications Warehouse

    Louthian, B.L.; Gann, E.E.

    1985-01-01

    This report describes water resources activities conducted by the Arkansas District of the U.S. Geological Survey, Water Resources Division, during fiscal years 1984 and 1985. Activities included surface water, groundwater, water quality, and water-use investigations. Twenty-five projects were funded during 1984 and 1985. For each project, a description of the project objectives, approach, plans and reports is included. Lists are included of reports completed during the period and of reports previously published by, or in conjunction with the Geological Survey. (USGS)

  15. Current water resources activities in Arkansas, 1986-87

    USGS Publications Warehouse

    Louthian, B.L.; Gann, E.E.

    1988-01-01

    This report describes water resources activities conducted by the Arkansas District of the U.S. Geological Survey, Water Resources Division during fiscal years 1986 and 1987. Activities included surface water, groundwater, water quality, and water-use investigations. Eighteen projects were funded during 1986 and 1987. For each project, a description of the project objectives, approach, plans and reports is included. Lists are included of reports completed during the period and of reports previously published by, or in conjunction with, the Geological Survey. (USGS)

  16. Board on Earth Sciences and Resources and its Activities

    NASA Technical Reports Server (NTRS)

    Schiffries, Craig M.

    1997-01-01

    The Board will provide oversight of the earth science and resource activities within the National Research Council, provide a review of research and public activities in the solid-earth sciences, and provide analyses and recommendations relevant to the supply, delivery, and associated impacts of and issues related to hydrocarbon, metallic, and non-metallic mineral resources. The Board will monitor the status of the earth sciences, assess the health of the disciplines, and identify research opportunities, and will respond to specific agency requests.

  17. Water resources activities in Kentucky, 1993-94

    USGS Publications Warehouse

    Maglothin, L. S., (compiler); Forbes, R.W.

    1994-01-01

    The U.S. Geological Survey (USGS) is the principal Federal water-resources data collection and investigation agency. Through the Water Resources Division District Office in Kentucky, the USGS investigates the occurrence, distribution, quantity, movement, and chemical and biological quality of surface and ground water in the State. The mission of this program is to collect, interpret, and publish information on water resources. Almost all research and data collection is a cooperative effort in which planning and financial support are shared by State and local agencies and governments. Other activities are funded by other Federal agencies or by direct Congressional appropriation. This report is intended to inform the public and cooperating agencies, vitally interested in the water resources of Kentucky, as to the current status of the Distfict's data collection and investigation program. Included in the report are summaries of water-resources activities in Kentucky conducted by the USGS. Also included is a description of the USGS mission and program, District organization, funding sources and cooperating agencies, and a list of USGS publications relevant to the water resources of the State.

  18. Current water resources activities in Alabama, fiscal year 1986

    USGS Publications Warehouse

    Slack, L.J.; Meadows, E.A.

    1986-01-01

    The purpose of this report is to describe the current (as of 1986) water resources activities of the U.S. Geological Survey in Alabama. The responsibilities and objectives of the Survey; organization of the Alabama District; sources of funding; current projects; hydrologic data program; and a selected bibliography of hydrologic reports are presented. Water resources projects are undertaken usually at the request of and with partial funding from another agency, provided: they are high priority problems and generally identified to fall within the mission of the Water Resources Division and they are consistent with the Program Management Plan developed by the Water Resources Division in Alabama to meet the long range plan for hydrologic data in the State. (USGS)

  19. Activities at the Universal Protein Resource (UniProt)

    PubMed Central

    2014-01-01

    The mission of the Universal Protein Resource (UniProt) (http://www.uniprot.org) is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequences and functional annotation. It integrates, interprets and standardizes data from literature and numerous resources to achieve the most comprehensive catalog possible of protein information. The central activities are the biocuration of the UniProt Knowledgebase and the dissemination of these data through our Web site and web services. UniProt is produced by the UniProt Consortium, which consists of groups from the European Bioinformatics Institute (EBI), the SIB Swiss Institute of Bioinformatics (SIB) and the Protein Information Resource (PIR). UniProt is updated and distributed every 4 weeks and can be accessed online for searches or downloads. PMID:24253303

  20. Five-Minute Activities: A Resource Book of Short Activities.

    ERIC Educational Resources Information Center

    Ur, Penny; Wright, Andrew

    This book provides about 130 short, easily-prepared activities to supplement the longer teaching procedures that make up the main body of an English course. Suitable for elementary to advanced levels, the activities presented in the book can serve as a quick warm-up for the students, an idea for a brief vocabulary review, a light filler to provide…

  1. Functional requirements of computer systems for the U.S. Geological Survey, Water Resources Division, 1988-97

    USGS Publications Warehouse

    Hathaway, R.M.; McNellis, J.M.

    1989-01-01

    Investigating the occurrence, quantity, quality, distribution, and movement of the Nation 's water resources is the principal mission of the U.S. Geological Survey 's Water Resources Division. Reports of these investigations are published and available to the public. To accomplish this mission, the Division requires substantial computer technology to process, store, and analyze data from more than 57,000 hydrologic sites. The Division 's computer resources are organized through the Distributed Information System Program Office that manages the nationwide network of computers. The contract that provides the major computer components for the Water Resources Division 's Distributed information System expires in 1991. Five work groups were organized to collect the information needed to procure a new generation of computer systems for the U. S. Geological Survey, Water Resources Division. Each group was assigned a major Division activity and asked to describe its functional requirements of computer systems for the next decade. The work groups and major activities are: (1) hydrologic information; (2) hydrologic applications; (3) geographic information systems; (4) reports and electronic publishing; and (5) administrative. The work groups identified 42 functions and described their functional requirements for 1988, 1992, and 1997. A few new functions such as Decision Support Systems and Executive Information Systems, were identified, but most are the same as performed today. Although the number of functions will remain about the same, steady growth in the size, complexity, and frequency of many functions is predicted for the next decade. No compensating increase in the Division 's staff is anticipated during this period. To handle the increased workload and perform these functions, new approaches will be developed that use advanced computer technology. The advanced technology is required in a unified, tightly coupled system that will support all functions simultaneously

  2. Resource Constrained Planning of Multiple Projects with Separable Activities

    NASA Astrophysics Data System (ADS)

    Fujii, Susumu; Morita, Hiroshi; Kanawa, Takuya

    In this study we consider a resource constrained planning problem of multiple projects with separable activities. This problem provides a plan to process the activities considering a resource availability with time window. We propose a solution algorithm based on the branch and bound method to obtain the optimal solution minimizing the completion time of all projects. We develop three methods for improvement of computational efficiency, that is, to obtain initial solution with minimum slack time rule, to estimate lower bound considering both time and resource constraints and to introduce an equivalence relation for bounding operation. The effectiveness of the proposed methods is demonstrated by numerical examples. Especially as the number of planning projects increases, the average computational time and the number of searched nodes are reduced.

  3. Advanced Extravehicular Activity Pressure Garment Requirements Development

    NASA Technical Reports Server (NTRS)

    Ross, Amy

    2014-01-01

    The NASA Johnson Space Center advanced pressure garment technology development team is addressing requirements development for exploration missions. Lessons learned from the Z-2 high fidelity prototype development have reiterated that clear low-level requirements and verification methods reduce risk to the government, improve efficiency in pressure garment design efforts, and enable the government to be a smart buyer. The expectation is to provide requirements at the specification level that are validated so that their impact on pressure garment design is understood. Additionally, the team will provide defined verification protocols for the requirements. However, in reviewing exploration space suit high level requirements there are several gaps in the team's ability to define and verify related lower level requirements. This paper addresses the efforts in requirement areas such as mobility/fit/comfort and environmental protection (dust, radiation, plasma, secondary impacts) to determine the by what method the requirements can be defined and use of those methods for verification. Gaps exist at various stages. In some cases component level work is underway, but no system level effort has begun, in other cases no effort has been initiated to close the gap. Status of ongoing efforts and potential approaches to open gaps are discussed.

  4. Teacher's Resource Guide on Acidic Precipitation with Laboratory Activities.

    ERIC Educational Resources Information Center

    Barrow, Lloyd H.

    The purpose of this teacher's resource guide is to help science teachers incorporate the topic of acidic precipitation into their curricula. A survey of recent junior high school science textbooks found a maximum of one paragraph devoted to the subject; in addition, none of these books had any related laboratory activities. It was on the basis of…

  5. Water Resource Uses and Recreational Activities in Rural Nigeria.

    ERIC Educational Resources Information Center

    Adekoya, Adebola

    1991-01-01

    This study surveys rural Nigerian residents concerning local water resource uses and tourists' recreational activities with respect to scales of awareness, understanding, and incentive. Results indicate a public willingness to encourage and finance the rural development of water bodies for agricultural purposes exclusive of investment for tourism…

  6. A RESOURCE BOOK OF AEROSPACE ACTIVITIES, K-6.

    ERIC Educational Resources Information Center

    Lincoln Public Schools, NE.

    THIS RESOURCE BOOK OF ACTIVITIES WAS WRITTEN FOR TEACHERS OF GRADES K-6, TO HELP THEM INTEGRATE AEROSPACE SCIENCE WITH THE REGULAR LEARNING EXPERIENCES OF THE CLASSROOM. SUGGESTIONS ARE MADE FOR INTRODUCING AEROSPACE CONCEPTS INTO THE VARIOUS SUBJECT FIELDS SUCH AS LANGUAGE ARTS, MATHEMATICS, PHYSICAL EDUCATION, SOCIAL STUDIES, AND OTHERS. SUBJECT…

  7. Learning for Change in World Society: Reflections, Activities and Resources.

    ERIC Educational Resources Information Center

    One World Trust, London (England).

    The resource booklet contains readings and activities for British secondary school world affairs classes. The material lends itself toward incorporation into various curricula, including history, geography, social studies, humanities, environmental studies, language and literature, home economics, math, and science. Subject matter focuses on…

  8. Suggestions, Resources and Activities for Teaching about Japan.

    ERIC Educational Resources Information Center

    Thomas, Paul F.

    This teacher resource packet contains a total of 28 modules for teaching about Japan at the elementary and secondary level. Activities on the Japanese family appropriate for grade 1 focus on similarities and differences, family size, family needs, and family roles. Grade 2 lessons look at the school, neighborhood, roles of children in the…

  9. Community Resources for Promoting Youth Nutrition and Physical Activity

    ERIC Educational Resources Information Center

    Moore, Kelly R.; McGowan, Melissa K.; Donato, Karen A.; Kollipara, Sobha; Roubideaux, Yvette

    2009-01-01

    Childhood obesity is a national public health crisis. The National Diabetes Education Program (NDEP), the National Institutes of Health and Kaiser Permanente have developed community tools and resources for children and families to lower their risk for obesity through healthier, active lifestyles. The authors describe innovative practices and…

  10. Impact of climate change on irrigation requirements in terms of groundwater resources

    NASA Astrophysics Data System (ADS)

    Zhou, Yu; Zwahlen, François; Wang, Yanxin; Li, Yilian

    2010-11-01

    Climate change affects not only water resources but also water demand for irrigation. A large proportion of the world’s agriculture depends on groundwater, especially in arid and semi-arid regions. In several regions, aquifer resources face depletion. Groundwater recharge has been viewed as a by-product of irrigation return flow, and with climate change, aquifer storage of such flow will be vital. A general review, for a broad-based audience, is given of work on global warming and groundwater resources, summarizing the methods used to analyze the climate change scenarios and the influence of these predicted changes on groundwater resources around the world (especially the impact on regional groundwater resources and irrigation requirements). Future challenges of adapting to climate change are also discussed. Such challenges include water-resources depletion, increasing irrigation demand, reduced crop yield, and groundwater salinization. The adaptation to and mitigation of these effects is also reported, including useful information for water-resources managers and the development of sustainable groundwater irrigation methods. Rescheduling irrigation according to the season, coordinating the groundwater resources and irrigation demand, developing more accurate and complete modeling prediction methods, and managing the irrigation facilities in different ways would all be considered, based on the particular cases.

  11. Board on Earth Sciences and Resources and its activities

    SciTech Connect

    de Souza, Dr. Anthony R.

    2000-02-23

    This 1999 annual report of the activities of the National Research Council's (NRC) Board on Earth Sciences and Resources (BESR) begins with an introduction to the Board. This report (1) lists activities of the Board sustained by Department of Energy support, (2) presents accomplishments of the Board, (3) describes current and proposed studies of the Board, and (4) provides a brief review of the Board's future plans.

  12. 10 CFR 810.8 - Activities requiring specific authorization.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Activities requiring specific authorization. 810.8 Section 810.8 Energy DEPARTMENT OF ENERGY ASSISTANCE TO FOREIGN ATOMIC ENERGY ACTIVITIES § 810.8 Activities requiring specific authorization. Unless generally authorized by § 810.7, a person requires specific authorization by the Secretary of Energy...

  13. 10 CFR 810.8 - Activities requiring specific authorization.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Activities requiring specific authorization. 810.8 Section 810.8 Energy DEPARTMENT OF ENERGY ASSISTANCE TO FOREIGN ATOMIC ENERGY ACTIVITIES § 810.8 Activities requiring specific authorization. Unless generally authorized by § 810.7, a person requires...

  14. 10 CFR 810.8 - Activities requiring specific authorization.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Activities requiring specific authorization. 810.8 Section 810.8 Energy DEPARTMENT OF ENERGY ASSISTANCE TO FOREIGN ATOMIC ENERGY ACTIVITIES § 810.8 Activities requiring specific authorization. Unless generally authorized by § 810.7, a person requires...

  15. 33 CFR 322.4 - Activities not requiring permits.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... established Federal harbor lines before May 27, 1970 (see 33 CFR 320.4(o)) do not require section 10 permits... States after October 18, 1972, a section 404 permit is required. (See 33 CFR part 323.) (b) Pursuant to section 154 of the Water Resource Development Act of 1976 (Pub. L. 94-587), Department of the Army...

  16. 33 CFR 322.4 - Activities not requiring permits.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... established Federal harbor lines before May 27, 1970 (see 33 CFR 320.4(o)) do not require section 10 permits... States after October 18, 1972, a section 404 permit is required. (See 33 CFR part 323.) (b) Pursuant to section 154 of the Water Resource Development Act of 1976 (Pub. L. 94-587), Department of the Army...

  17. 33 CFR 322.4 - Activities not requiring permits.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... established Federal harbor lines before May 27, 1970 (see 33 CFR 320.4(o)) do not require section 10 permits... States after October 18, 1972, a section 404 permit is required. (See 33 CFR part 323.) (b) Pursuant to section 154 of the Water Resource Development Act of 1976 (Pub. L. 94-587), Department of the Army...

  18. 33 CFR 322.4 - Activities not requiring permits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... established Federal harbor lines before May 27, 1970 (see 33 CFR 320.4(o)) do not require section 10 permits... States after October 18, 1972, a section 404 permit is required. (See 33 CFR part 323.) (b) Pursuant to section 154 of the Water Resource Development Act of 1976 (Pub. L. 94-587), Department of the Army...

  19. 33 CFR 322.4 - Activities not requiring permits.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... established Federal harbor lines before May 27, 1970 (see 33 CFR 320.4(o)) do not require section 10 permits... States after October 18, 1972, a section 404 permit is required. (See 33 CFR part 323.) (b) Pursuant to section 154 of the Water Resource Development Act of 1976 (Pub. L. 94-587), Department of the Army...

  20. Active material based active sealing technology: Part 1. Active seal requirements vs. active material actuator properties

    NASA Astrophysics Data System (ADS)

    Henry, Christopher P.; Carter, William; Herrera, Guillermo A.; McKnight, Geoffrey P.; Browne, Alan L.; Johnson, Nancy L.; Bazzi, Imad F.

    2010-04-01

    Current seals used for vehicle closures/swing panels are essentially flexible, frequently hollow structures whose designs are constrained by numerous requirements, many of them competing, including door closing effort (both air bind and seal compression), sound isolation, prevention of water leaks, and accommodation of variations in vehicle build. This paper documents the first portion of a collaborative research study/exploration of the feasibility of and approaches for using active materials with shape and stiffness changing attributes to produce active seal technologies, seals with improved performance. An important design advantage of an active material approach compared to previous active seal technologies is the distribution of active material regions throughout the seal length, which would enable continued active function even with localized failure. Included as a major focus of this study was the assessment of polymeric active materials because of their potential ease of integration into the current seal manufacturing process. In Part 1 of this study, which is documented in this paper, potential materials were evaluated in terms of their cost, activation mechanisms, and mechanical and actuation properties. Based on these properties, simple designs were proposed and utilized to help determine which materials are best suited for active seals. Shape memory alloys (SMA) and electroactive polymers (EAP) were judged to be the most promising.

  1. Constraints on global fire activity vary across a resource gradient.

    PubMed

    Krawchuk, Meg A; Moritz, Max A

    2011-01-01

    We provide an empirical, global test of the varying constraints hypothesis, which predicts systematic heterogeneity in the relative importance of biomass resources to burn and atmospheric conditions suitable to burning (weather/climate) across a spatial gradient of long-term resource availability. Analyses were based on relationships between monthly global wildfire activity, soil moisture, and mid-tropospheric circulation data from 2001 to 2007, synthesized across a gradient of long-term averages in resources (net primary productivity), annual temperature, and terrestrial biome. We demonstrate support for the varying constraints hypothesis, showing that, while key biophysical factors must coincide for wildfires to occur, the relative influence of resources to burn and moisture/weather conditions on fire activity shows predictable spatial patterns. In areas where resources are always available for burning during the fire season, such as subtropical/tropical biomes with mid-high annual long-term net primary productivity, fuel moisture conditions exert their strongest constraint on fire activity. In areas where resources are more limiting or variable, such as deserts, xeric shrublands, or grasslands/savannas, fuel moisture has a diminished constraint on wildfire, and metrics indicating availability of burnable fuels produced during the antecedent wet growing seasons reflect a more pronounced constraint on wildfire. This macro-scaled evidence for spatially varying constraints provides a synthesis with studies performed at local and regional scales, enhances our understanding of fire as a global process, and indicates how sensitivity to future changes in temperature and precipitation may differ across the world. PMID:21560682

  2. Risk assessment activities at NIOSH: Information resources and needs

    SciTech Connect

    Stayner, L.T.; Meinhardt, T.; Hardin, B.

    1990-12-31

    Under the Occupational Safety and Health, and Mine Safety and Health Acts, the National Institute for Occupational Safety and Health (NIOSH) is charged with development of recommended occupational safety and health standards, and with conducting research to support the development of these standards. Thus, NIOSH has been actively involved in the analysis of risk associated with occupational exposures, and in the development of research information that is critical for the risk assessment process. NIOSH research programs and other information resources relevant to the risk assessment process are described in this paper. Future needs for information resources are also discussed.

  3. Idaho National Laboratory Cultural Resource Management Office FY 2011 Activity Report

    SciTech Connect

    Julie Braun Williams; Brenda R. Pace; Hollie K. Gilbert; Christina L. Olson

    2012-09-01

    The Idaho National Laboratory (INL) Site is home to vast numbers and a wide variety of important cultural resources representing at least a 13,500 year span of human land use in the region. As a federal agency, the Department of Energy, Idaho Operations Office (DOE-ID) has legal responsibility for the management and protection of the resources and has contracted these responsibilities to Battelle Energy Alliance (BEA). The BEA professional staff is committed to maintaining a cultural resource management program that accepts the challenge of preserving INL cultural resources in a manner reflecting their importance in local, regional, and national history. This report is intended as a stand-alone document that summarizes activities performed by the INL Cultural Resource Management Office (CRMO) staff during fiscal year 2011. This work is diverse, far-reaching and though generally confined to INL cultural resource compliance, also includes a myriad of professional and voluntary community activities. This document is intended to be informative to both internal and external stakeholders, serve as a planning tool for future INL cultural resource management work, and meet an agreed upon legal requirement.

  4. Frequency requirements for active earth observation sensors

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The foundation and rationale for the selection of microwave frequencies for active remote sensing usage and for subsequent use in determination of sharing criteria and allocation strategies for the WARC-79 are presented.

  5. 42 CFR 441.56 - Required activities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    .... (See paragraph (c)(3) of this section for requirements relating to provision of immunization at the... dental health; and (3) Appropriate immunizations. (If it is determined at the time of screening that immunization is needed and appropriate to provide at the time of screening, then immunization treatment must...

  6. 42 CFR 441.56 - Required activities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... youth. (See paragraph (c)(3) of this section for requirements relating to provision of immunization at... of dental health; and (3) Appropriate immunizations. (If it is determined at the time of screening that immunization is needed and appropriate to provide at the time of screening, then...

  7. 42 CFR 441.56 - Required activities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .... (See paragraph (c)(3) of this section for requirements relating to provision of immunization at the... dental health; and (3) Appropriate immunizations. (If it is determined at the time of screening that immunization is needed and appropriate to provide at the time of screening, then immunization treatment must...

  8. 42 CFR 441.56 - Required activities.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... youth. (See paragraph (c)(3) of this section for requirements relating to provision of immunization at... of dental health; and (3) Appropriate immunizations. (If it is determined at the time of screening that immunization is needed and appropriate to provide at the time of screening, then...

  9. 42 CFR 441.56 - Required activities.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... youth. (See paragraph (c)(3) of this section for requirements relating to provision of immunization at... of dental health; and (3) Appropriate immunizations. (If it is determined at the time of screening that immunization is needed and appropriate to provide at the time of screening, then...

  10. Analysis of requirements for accelerating the development of geothermal energy resources in California

    NASA Technical Reports Server (NTRS)

    Fredrickson, C. D.

    1978-01-01

    Various resource data are presented showing that geothermal energy has the potential of satisfying a singificant part of California's increasing energy needs. General factors slowing the development of geothermal energy in California are discussed and required actions to accelerate its progress are presented. Finally, scenarios for developing the most promising prospects in the state directed at timely on-line power are given. Specific actions required to realize each of these individual scenarios are identified.

  11. Competencies Required of Human Resource Professionals in the Government Contracting Industry

    ERIC Educational Resources Information Center

    Boyer, Dawn Denise

    2013-01-01

    The purpose of this study was to determine if a unique set of Knowledge, Skills, and Abilities (KSAs) were required of Human Resource Practitioners (HRPs) in federal-level Government Contracting Companies (GCC) in the United States. Study results identified additional sets of HR-related KSAs to perform with minimum competency within a…

  12. South Carolina Commission on Higher Education Mission Resource Requirements (MRR), FY 2007-2008

    ERIC Educational Resources Information Center

    South Carolina Commission on Higher Education, 2007

    2007-01-01

    The Mission Resource Requirement (MRR) represents the level of funding necessary for an institution given its mission, size, and complexity of programs, based on regional and national norms, and the amount of the previous year's appropriation. This document is the MRR for the South Carolina Commission on Higher Education for Fiscal Year 2007-2008.…

  13. 48 CFR 3004.470 - Security requirements for access to unclassified facilities, Information Technology resources...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Security requirements for access to unclassified facilities, Information Technology resources, and sensitive information. 3004.470 Section 3004.470 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY ACQUISITION REGULATION (HSAR)...

  14. 48 CFR 3004.470 - Security requirements for access to unclassified facilities, Information Technology resources...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Security requirements for access to unclassified facilities, Information Technology resources, and sensitive information. 3004.470 Section 3004.470 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY ACQUISITION REGULATION (HSAR)...

  15. 48 CFR 1252.239-70 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... resources. As prescribed in (TAR) 48 CFR 1239.70, insert the following clause: Security Requirements for... DOT e-Government sites or other IT operations; (2) Acquisition, transmission or analysis of data owned..., recording, and analysis of all data being communicated, transmitted, processed or stored in this system...

  16. 14 CFR § 1274.937 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Security requirements for unclassified information technology resources. § 1274.937 Section § 1274.937 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION COOPERATIVE AGREEMENTS WITH COMMERCIAL FIRMS Other Provisions and Special Conditions § 1274.937 Security...

  17. 48 CFR 3052.204-70 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... for unclassified information technology resources. As prescribed in (HSAR) 48 CFR 3004.470-3, insert a... laws that include, but are not limited to, the Computer Security Act of 1987 (40 U.S.C. 1441 et seq... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Security requirements...

  18. 48 CFR 1252.239-70 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Security requirements for unclassified information technology resources. 1252.239-70 Section 1252.239-70 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses...

  19. 48 CFR 1352.239-72 - Security requirements for information technology resources.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Clauses 1352.239-72 Security requirements for information technology resources. As prescribed in 48 CFR... term “Sensitive” is defined by the guidance set forth in the Computer Security Act of 1987 (Pub. L. 100..., computer ethics, and best practices, in accordance with DOC IT Security Program Policy, chapter 15,...

  20. 48 CFR 1352.239-72 - Security requirements for information technology resources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Clauses 1352.239-72 Security requirements for information technology resources. As prescribed in 48 CFR... term “Sensitive” is defined by the guidance set forth in the Computer Security Act of 1987 (Pub. L. 100..., computer ethics, and best practices, in accordance with DOC IT Security Program Policy, chapter 15,...

  1. 48 CFR 3052.204-70 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... for unclassified information technology resources. As prescribed in (HSAR) 48 CFR 3004.470-3, insert a... laws that include, but are not limited to, the Computer Security Act of 1987 (40 U.S.C. 1441 et seq... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Security requirements...

  2. 48 CFR 3052.204-70 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... for unclassified information technology resources. As prescribed in (HSAR) 48 CFR 3004.470-3, insert a... laws that include, but are not limited to, the Computer Security Act of 1987 (40 U.S.C. 1441 et seq... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Security requirements...

  3. 48 CFR 1352.239-72 - Security requirements for information technology resources.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Security requirements for information technology resources. 1352.239-72 Section 1352.239-72 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 1352.239-72...

  4. Study of Nursing Manpower Requirements and Resources in Kentucky, 1981 and 1985. Kentucky Nursing Education Project.

    ERIC Educational Resources Information Center

    Kentucky State Council on Higher Education, Frankfort.

    The Kentucky Nursing Manpower Requirements and Resources Study (1981 and 1985) is one segment of a nursing project designed to develop a coordinated statewide system of nursing education in Kentucky. The study determined the number and types of nurses needed and compared current and anticipated nursing manpower supply and demand. Calculations of…

  5. TERSSE: Definition of the Total Earth Resources System for the Shuttle Era. Volume 3: Mission and System Requirements for the Total Earth Resources System

    NASA Technical Reports Server (NTRS)

    1974-01-01

    Resource management missions to be performed by TERSSE are described. Mission and user requirements are defined along with information flows developed for each major resource management mission. Other topics discussed include: remote sensing platforms, remote sensor requirements, ground system architecture, and such related issues as cloud cover, resolution, orbit mechanics, and aircraft versus satellite.

  6. Activation Requirements for Metabotropic Glutamate Receptors

    PubMed Central

    Viaene, Angela N.; Petrof, Iraklis; Sherman, S. Murray

    2013-01-01

    It has been common experimentally to use high frequency, tetanic, stimulation to activate metabotropic glutamate receptors (mGluRs) in cortex and thalamus. To determine what type of stimulation is actually necessary to activate mGluRs we examined the effects of varying stimulation duration and intensity on activating mGluR responses. We used a thalamocortical and an intracortical slice preparation from mice and performed whole cell recordings from neurons in the ventral posterior medial nucleus or in layer 4 of primary somatosensory cortex (S1) while electrically stimulating in layer 6 of S1. Extracellular ionotropic glutamate receptor antagonists and GABAA receptor antagonists were used to isolate Group I or Group II mGluR responses. We observed that high frequency stimulation is not necessary for the activation of either Group I or Group II mGluRs. Either could be activated with as few as 2-3 pulses at stimulation frequencies around 15-20Hz. Additionally, increasing the number of pulses, intensity of stimulation, or stimulation frequency increased amplitude and duration of the mGluR response. PMID:23416319

  7. Activities affecting surface water resources: A general overview

    SciTech Connect

    Not Available

    1990-01-01

    In November 1987, P.E.I. signed a federal/provincial work-sharing arrangement on water resource management focusing on groundwater pollution, surface water degradation and estuarine eutrophication. The surface water program was designed to identify current surface water uses and users within 12 major watersheds across the Island containing 26 individual rivers, as well as problems arising due to practices that degrade the quality of surface water and restricts its value to other user groups. This report presents a general overview of the program, covering the general characteristics of the Island; operations in agriculture, fish and wildlife, forestry, recreation, fisheries, and industry; alterations of natural features of waterways; wetlands; additional watershed activities such as hydrometric stations and subdivision development; and activities affecting surface water resources such as sedimentation sources, pollution point sources and instream obstructions.

  8. Human olfactory lateralization requires trigeminal activation.

    PubMed

    Croy, Ilona; Schulz, Max; Blumrich, Anna; Hummel, Cornelia; Gerber, Johannes; Hummel, Thomas

    2014-09-01

    Rats are able to lateralize odors. This ability involves specialized neurons in the orbitofrontal cortex which are able to process the left, right and bilateral presentation of stimuli. However, it is not clear whether this function is preserved in humans. Humans are in general not able to differentiate whether a selective olfactory stimulant has been applied to the left or right nostril; however exceptions have been reported. Following a screening of 152 individuals with an olfactory lateralization test, we identified 19 who could lateralize odors above chance level. 15 of these "lateralizers" underwent olfactory fMRI scanning in a block design and were compared to 15 controls matched for age and sex distribution. As a result, both groups showed comparable activation of olfactory eloquent brain areas. However, subjects with lateralization ability had a significantly enhanced activation of cerebral trigeminal processing areas (somatosensory cortex, intraparietal sulcus). In contrast to controls, lateralizers furthermore exhibited no suppression in the area of the trigeminal principal sensory nucleus. An exploratory study with an olfactory change detection paradigm furthermore showed that lateralizers oriented faster towards changes in the olfactory environment. Taken together, our study suggests that the trigeminal system is activated to a higher degree by the odorous stimuli in the group of "lateralizers". We conclude that humans are not able to lateralize odors based on the olfactory input alone, but vary in the degree to which the trigeminal system is recruited. PMID:24825502

  9. Technical guide on documentation requirements for open market contract acquisitions of information resources

    NASA Technical Reports Server (NTRS)

    Shaw, Asa L., Jr.; Kivett, William R.; Taylor, James Y.

    1990-01-01

    A guide is presented to assist requestors in formulating and submitting the required Complete Package for Information Resources (IR) acquisitions. Advance discussions with cognizant procurement personnel are strongly recommended for complex IR requirements or for those requestors new to the acquisition process. Open Market means the requirement either is not available on GSA Schedule Contract or exceeds the $300,000 threshold and/or the quantity Maximum Order Limitation of the GSA Schedule Contract. Only open market contract acquisitions (i.e., in excess of the $25,000 small purchase threshold), are addressed.

  10. Antiproliferative activity of synthetic fatty acid amides from renewable resources.

    PubMed

    dos Santos, Daiane S; Piovesan, Luciana A; D'Oca, Caroline R Montes; Hack, Carolina R Lopes; Treptow, Tamara G M; Rodrigues, Marieli O; Vendramini-Costa, Débora B; Ruiz, Ana Lucia T G; de Carvalho, João Ernesto; D'Oca, Marcelo G Montes

    2015-01-15

    In the work, the in vitro antiproliferative activity of a series of synthetic fatty acid amides were investigated in seven cancer cell lines. The study revealed that most of the compounds showed antiproliferative activity against tested tumor cell lines, mainly on human glioma cells (U251) and human ovarian cancer cells with a multiple drug-resistant phenotype (NCI-ADR/RES). In addition, the fatty methyl benzylamide derived from ricinoleic acid (with the fatty acid obtained from castor oil, a renewable resource) showed a high selectivity with potent growth inhibition and cell death for the glioma cell line-the most aggressive CNS cancer. PMID:25510639

  11. 77 FR 33774 - Agency Information Collection Activities: Comment Request; Education and Human Resources Project...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-07

    ... Agency Information Collection Activities: Comment Request; Education and Human Resources Project... of Collection: Education and Human Resources Project Monitoring Clearance. OMB Approval Number: 3145... States and internationally. The Directorate for Education and Human Resources (EHR), a unit within...

  12. Estimation of crop water requirements using remote sensing for operational water resources management

    NASA Astrophysics Data System (ADS)

    Vasiliades, Lampros; Spiliotopoulos, Marios; Tzabiras, John; Loukas, Athanasios; Mylopoulos, Nikitas

    2015-06-01

    An integrated modeling system, developed in the framework of "Hydromentor" research project, is applied to evaluate crop water requirements for operational water resources management at Lake Karla watershed, Greece. The framework includes coupled components for operation of hydrotechnical projects (reservoir operation and irrigation works) and estimation of agricultural water demands at several spatial scales using remote sensing. The study area was sub-divided into irrigation zones based on land use maps derived from Landsat 5 TM images for the year 2007. Satellite-based energy balance for mapping evapotranspiration with internalized calibration (METRIC) was used to derive actual evapotranspiration (ET) and crop coefficient (ETrF) values from Landsat TM imagery. Agricultural water needs were estimated using the FAO method for each zone and each control node of the system for a number of water resources management strategies. Two operational strategies of hydro-technical project development (present situation without operation of the reservoir and future situation with the operation of the reservoir) are coupled with three water demand strategies. In total, eight (8) water management strategies are evaluated and compared. The results show that, under the existing operational water resources management strategies, the crop water requirements are quite large. However, the operation of the proposed hydro-technical projects in Lake Karla watershed coupled with water demand management measures, like improvement of existing water distribution systems, change of irrigation methods, and changes of crop cultivation could alleviate the problem and lead to sustainable and ecological use of water resources in the study area.

  13. Bibliography on Multicultural Activities in the Classroom: A Listing of Resources.

    ERIC Educational Resources Information Center

    Brady, Mary Lou; Geile, Carole

    This bibliography contains information on multicultural activities in the classroom. It is divided into three sections: a list of 97 book resources, a list of 59 journal articles, and a list of 17 ERIC (Educational Resources Information Center) resources. The resources include general multicultural teaching guides and specific topical resources:…

  14. 10 CFR 490.507 - Credit activity reporting requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 3 2013-01-01 2013-01-01 false Credit activity reporting requirements. 490.507 Section 490.507 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Alternative Fueled Vehicle Credit Program § 490.507 Credit activity reporting requirements. (a) A...

  15. 10 CFR 490.507 - Credit activity reporting requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Credit activity reporting requirements. 490.507 Section 490.507 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Alternative Fueled Vehicle Credit Program § 490.507 Credit activity reporting requirements. (a) A...

  16. 10 CFR 490.507 - Credit activity reporting requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 3 2012-01-01 2012-01-01 false Credit activity reporting requirements. 490.507 Section 490.507 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Alternative Fueled Vehicle Credit Program § 490.507 Credit activity reporting requirements. (a) A...

  17. 27 CFR 40.526 - Minimum manufacturing and activity requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2014-04-01 2014-04-01 false Minimum manufacturing and activity requirements. 40.526 Section 40.526 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX... Manufacturers of Processed Tobacco § 40.526 Minimum manufacturing and activity requirements. A permit...

  18. 27 CFR 40.256 - Minimum manufacturing and activity requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Minimum manufacturing and... Provisions Relating to Operations § 40.256 Minimum manufacturing and activity requirements. The minimum manufacturing and activity requirement prescribed in § 40.61(b) of this part is a continuing condition of...

  19. 27 CFR 40.526 - Minimum manufacturing and activity requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Minimum manufacturing and activity requirements. 40.526 Section 40.526 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX... Manufacturers of Processed Tobacco § 40.526 Minimum manufacturing and activity requirements. A permit...

  20. 27 CFR 40.526 - Minimum manufacturing and activity requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2011-04-01 2011-04-01 false Minimum manufacturing and activity requirements. 40.526 Section 40.526 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX... Manufacturers of Processed Tobacco § 40.526 Minimum manufacturing and activity requirements. A permit...

  1. 27 CFR 40.256 - Minimum manufacturing and activity requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2014-04-01 2014-04-01 false Minimum manufacturing and... Provisions Relating to Operations § 40.256 Minimum manufacturing and activity requirements. The minimum manufacturing and activity requirement prescribed in § 40.61(c) of this part is a continuing condition of...

  2. 27 CFR 40.256 - Minimum manufacturing and activity requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2013-04-01 2013-04-01 false Minimum manufacturing and... Provisions Relating to Operations § 40.256 Minimum manufacturing and activity requirements. The minimum manufacturing and activity requirement prescribed in § 40.61(c) of this part is a continuing condition of...

  3. 27 CFR 40.256 - Minimum manufacturing and activity requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2012-04-01 2011-04-01 true Minimum manufacturing and... Provisions Relating to Operations § 40.256 Minimum manufacturing and activity requirements. The minimum manufacturing and activity requirement prescribed in § 40.61(b) of this part is a continuing condition of...

  4. 27 CFR 40.526 - Minimum manufacturing and activity requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2013-04-01 2013-04-01 false Minimum manufacturing and activity requirements. 40.526 Section 40.526 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX... Manufacturers of Processed Tobacco § 40.526 Minimum manufacturing and activity requirements. A permit...

  5. 27 CFR 40.526 - Minimum manufacturing and activity requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2012-04-01 2011-04-01 true Minimum manufacturing and activity requirements. 40.526 Section 40.526 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX... Manufacturers of Processed Tobacco § 40.526 Minimum manufacturing and activity requirements. A permit...

  6. 27 CFR 40.256 - Minimum manufacturing and activity requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2011-04-01 2011-04-01 false Minimum manufacturing and... Provisions Relating to Operations § 40.256 Minimum manufacturing and activity requirements. The minimum manufacturing and activity requirement prescribed in § 40.61(b) of this part is a continuing condition of...

  7. 20 CFR 655.1302 - Required pre-filing activity.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Employment in the United States (H-2A Workers) § 655.1302 Required pre-filing activity. (a) Time of filing of... requirements for agricultural clearance orders in 20 CFR part 653 Subpart F and the requirements set forth in § 655.104. (3) The SWA will review the contents of the job order as provided in 20 CFR part 653...

  8. The Gaia mission a rich resource for outreach activities

    NASA Astrophysics Data System (ADS)

    O'Flaherty, K. S.; Douglas, J.; Prusti, T.

    2008-07-01

    Space science missions, and astronomy missions in particular, capture the public imagination at all levels. ESA's Gaia mission is no exception to this. In addition to its key scientific goal of providing new insight into the origin, formation, and evolution of the Milky Way, Gaia also touches on many other scientific topics of broad appeal, for example, solar system objects, stars (including rare and exotic ones), dark matter, gravitational light bending. The mission naturally provides a rich resource for outreach possibilities whether it be to the general public, or to specific interest groups, such as scientists from other fields or educators. We present some examples of possible outreach activities for Gaia.

  9. Elementary school aerospace activities: A resource for teachers

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The chronological development of the story of man and flight, with emphasis on space flight, is presented in 10 units designed as a resource for elementary school teachers. Future exploration of space and the utlization of space flight capabilities are included. Each unit contains an outline, a list of suggested activities for correlation, a bibliography, and a list of selected audiovisual materials. A glossary of aerospace terms is included. Topics cover: earth characteristics that affect flight; flight in atmosphere, rockets, technological advances, unmanned Earth satellites, umanned exploration of the solar system, life support systems; astronauts, man in space, and projections for the future.

  10. Board on Earth Sciences and Resources and its activities

    SciTech Connect

    1995-06-01

    The Board on Earth Sciences and Resources (BESR) coordinates, the National Research Council`s advice to the federal government on solid-earth science issues. The board identifies opportunities for advancing basic research and understanding, reports on applications of earth sciences in such areas as disaster mitigation and resource utilization, and analyzes the scientific underpinnings and credibility of earth science information for resource, environmental and other applications and policy decision. Committees operating under the guidance of the Board conducts studies addressing specific issues within the earth sciences. The current committees are as follows: Committee on Geophysical and Environmental Data; Mapping Sciences Committee; Committee on Seismology; Committee on Geodesy; Rediscovering Geography Committee; Committee on Research Programs of the US Bureau of Mines. The following recent reports are briefly described: research programs of the US Bureau of Mines, first assessment 1994; Mount Rainier, active cascade volcano; the national geomagnetic initiative; reservoir class field demonstration program; solid-earth sciences and society; data foundation for the national spatial infrastructure; promoting the national spatial data infrastructure through partnerships; toward a coordinated spatial data infrastructure for the nation; and charting a course into the digital era; guidance to the NOAA`s nautical charting mission.

  11. Editors and author resource centers actively used by attendees

    NASA Astrophysics Data System (ADS)

    Major, Barbara

    2012-02-01

    At the 2011 Fall Meeting, as in previous years, the Editors Resource Center located on the second floor of Moscone West was buzzing with activity: editors talking with other editors, collaborating with associate editors, speaking with authors, and meeting with students. In addition, several editors took part in "Meet the Editor" informal sessions, a new feature introduced for the 2011 meeting to strengthen the partnership between authors and editors. The map "Where are you from?" (see photo), outside the Editors Resource Center, drew the attention of many attendees who were eager to place their colored dots on the map. The Author Resource Center, located in the AGU Marketplace, became a hub for AGU veteran authors and potential authors alike. Staff were there to answer both editorial and technical questions, especially the most frequent one: What happens after my paper is accepted? The running slideshow that described all aspects of the AGU publications program sparked a myriad of questions, which AGU staff were happy to answer.

  12. 42 CFR 436.222 - Individuals under age 21 who meet the income and resource requirements of AFDC.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... resource requirements of AFDC. 436.222 Section 436.222 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN....222 Individuals under age 21 who meet the income and resource requirements of AFDC. (a) The agency...

  13. 42 CFR 435.222 - Individuals under age 21 who meet the income and resource requirements of AFDC.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... resource requirements of AFDC. 435.222 Section 435.222 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN... age 21 who meet the income and resource requirements of AFDC. (a) The agency may provide Medicaid...

  14. 42 CFR 435.222 - Individuals under age 21 who meet the income and resource requirements of AFDC.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... resource requirements of AFDC. 435.222 Section 435.222 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN... age 21 who meet the income and resource requirements of AFDC. (a) The agency may provide Medicaid...

  15. 42 CFR 435.222 - Individuals under age 21 who meet the income and resource requirements of AFDC.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... resource requirements of AFDC. 435.222 Section 435.222 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN... income and resource requirements of AFDC. (a) The agency may provide Medicaid to individuals under age...

  16. 42 CFR 436.222 - Individuals under age 21 who meet the income and resource requirements of AFDC.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... resource requirements of AFDC. 436.222 Section 436.222 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN....222 Individuals under age 21 who meet the income and resource requirements of AFDC. (a) The agency...

  17. 42 CFR 435.222 - Individuals under age 21 who meet the income and resource requirements of AFDC.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... resource requirements of AFDC. 435.222 Section 435.222 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN... age 21 who meet the income and resource requirements of AFDC. (a) The agency may provide Medicaid...

  18. 42 CFR 436.222 - Individuals under age 21 who meet the income and resource requirements of AFDC.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... resource requirements of AFDC. 436.222 Section 436.222 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN....222 Individuals under age 21 who meet the income and resource requirements of AFDC. (a) The agency...

  19. 42 CFR 435.222 - Individuals under age 21 who meet the income and resource requirements of AFDC.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... resource requirements of AFDC. 435.222 Section 435.222 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN... income and resource requirements of AFDC. (a) The agency may provide Medicaid to individuals under age...

  20. 42 CFR 436.222 - Individuals under age 21 who meet the income and resource requirements of AFDC.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... resource requirements of AFDC. 436.222 Section 436.222 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN....222 Individuals under age 21 who meet the income and resource requirements of AFDC. (a) The agency...

  1. 42 CFR 436.222 - Individuals under age 21 who meet the income and resource requirements of AFDC.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... resource requirements of AFDC. 436.222 Section 436.222 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN....222 Individuals under age 21 who meet the income and resource requirements of AFDC. (a) The agency...

  2. Exploratory Activity in Drosophila Requires the kurtz Nonvisual Arrestin

    PubMed Central

    Liu, Lingzhi; Davis, Ronald L.; Roman, Gregg

    2007-01-01

    When Drosophila adults are placed into an open field arena, they initially exhibit an elevated level of activity followed by a reduced stable level of spontaneous activity. We have found that the initial elevated component arises from the fly's interaction with the novel arena since: (1) the increased activity is independent of handling prior to placement within the arena, (2) the fly's elevated activity is proportional to the size of the arena, and (3) the decay in activity to spontaneous levels requires both visual and olfactory input. These data indicate that active exploration is the major component of elevated initial activity. There is a specific requirement for the kurtz nonvisual arrestin in the nervous system for both the exploration stimulated by the novel arena and the mechanically stimulated activity. kurtz is not required for spontaneous activity; kurtz mutants display normal levels of spontaneous activity and average the same velocities as wild-type controls. Inhibition of dopamine signaling has no effect on the elevated initial activity phase in either wild-type or krz1 mutants. Therefore, the exploratory phase of open field activity requires kurtz in the nervous system, but is independent of dopamine's stimulation of activity. PMID:17151232

  3. Lunar in situ resource utilization by activated thermites

    NASA Astrophysics Data System (ADS)

    Hobosyan, Mkhitar; Martirosyan, Karen

    2011-10-01

    NASA's anticipated returns to the Moon by 2020, subsequent establishment of lunar in situ resource utilization technologies are essential. The surface of Moon is covered with small eroded particles of regolith called lunar dust that adheres electro-statically to everything coming in contact with it, and is of much concern for future lunar base because of its continual mitigation. The next major concern is the protection of equipment and personnel in long term expeditions from harmful UV radiation, which can be made by constructing protective buildings. For construction of permanent structures it is highly desired to have regular shaped sintered regolith with utilization of local materials and with minimum energy consumption. In this study the concept of sintering of lunar regolith with activated thermite reactions is discussed. The thermodynamic calculations as well as the experimental procedure is provided to prove the effectiveness of activated thermites for regolith sintering using local lunar resources with a low (15 wt. %) concentration of aluminum or magnesium. The thermite method is much more energy efficient than the other sintering methods suggested in literature.

  4. Integrating Natural Resource Damage Assessment and environmental restoration activities at DOE facilities

    SciTech Connect

    Bascietto, J.J.; Sharples, F.E.; Suter, G.W. II

    1993-06-01

    Environmental restoration activities are currently under way at several sites owned by the US Department of Energy (DOE) under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended. DOE is the CERCLA lead response agency for these activities. Section 120(a) of the Superfund Amendments and Reauthorization Act also subjects DOE to liability under Section 107 of CERCLA for natural resource damages resulting from hazardous substance releases at its sites. The Natural Resource Damage Assessment (NRDA) process, by which natural resource injuries are determined and compensatory monetary damages are calculated, is not well known or understood by DOE staff and contractors involved in environmental restoration activities. Nevertheless, natural resource liabilities are potentially a significant source of additional monetary claims for CERCLA hazardous substance releases. This paper describes the requirements of NRDA and explains how to integrate the NRDA and CERCLA Remedial Investigation/Feasibility Study processes, in order to more quickly restore environmental services at the lowest total cost to the public. The first section of the paper explains the statutory and regulatory mandates for the NRDA process. The second section briefly describes the four phases of the NRDA process, while the third section examines the three steps in the assessment phase in considerable detail. Finally, the last section focuses on the integration of the CERCLA and NRDA processes.

  5. Water Requirements for Energy Production Technologies: A Collaborative Effort to Support Integrated Resource Planning

    NASA Astrophysics Data System (ADS)

    Averyt, K.; Macknick, J.; Participants in The WaterEnergy Workshop

    2010-12-01

    Global, national and regional concerns are emerging about the capacity of available water resources to meet increasing energy demands posed by a growing population—particularly as water availability is expected to shift as a result of a warming climate. For the same reasons, the use of both non-traditional water resources and water transport is expected to increase, creating greater demand for energy to move and treat water. Integrated planning efforts designed to avoid collisions between water and energy resource management decisions require consistent data outlining both the water requirements for energy development, and the energy required to move and treat water. Here we present the results of a collaborative, interagency effort to compile, assess, and outline consumptive uses of water associated with different parts of the energy generation process. A consistent set of data is important to support integrated modeling efforts in support of decision making and planning. The leaders of several efforts occurring in parallel to collate water use data converged at a workshop held in August 2010. The participants shared estimates of water use related to the major water-consuming steps of all the energy production processes currently operating in the U.S., and those expected to be online in the future. Discussions also addressed underlying data assumptions, data reliability concerns, and regional variability in reported ranges of values. Participants identified key data gaps, determining whether outside expert engagement could fill the gaps, or if additional research was required. The team collaborated after the meeting to fill in the data gaps utilizing institutional knowledge from a wide variety of agencies. The end result is a compilation of best estimates of the water requirements for energy production, as agreed to by the expert participants at the workshop and subsequent interactions. One key informational gap emerging from the workshop is the need to

  6. Water-resources activities in New England, fiscal year 1993

    USGS Publications Warehouse

    Orlando, M.F.

    1994-01-01

    The U.S. Geological Survey has 82 active or complete-except-report projects of hydrologic investigations ongoing within the New England Program Area. Of this total, 23 are data projects. Data projects contain statistics and data on the conditions of surface water, ground water, water quality and (or) water use for the study area. There currently are six data projects in Connecticut, five in Maine, four in Massachusetts, four in Rhode Island, and four in New Hampshire and Vermont. The remaining 59 of these projects are interpretive projects. Interpretive projects include research, aerial appraisal, and other hydrologic studies and include projects as diverse as (1) determining the direction of ground-water flow at a toxic site, (2) predicting the effect of acid rain on water quality of a reservoir, and (3) estimating yields of aquifers on Cape Cod. Of the interpretive projects, 26 are in Massachusetts, 17 in Connecticut, 17 are in New Hampshire and Vermont, 6 are in Maine, and 3 in Rhode Island. The report is compiled from project descriptions for fiscal year 1993. It briefly describes the water-resources activities and projects that were active in each District of the USGS, Water Resources Division, New England Program Area of September 30, 1993. Cooperator or funding source, problem statements, objectives, approaches, progress, and plans for next year are described for each project. The project area is located on a map of the appropriate State(s). The report contains a bibliography, by District and by author, of reports completed since 1977.

  7. Resource Letter ALIP-1: Active-Learning Instruction in Physics

    NASA Astrophysics Data System (ADS)

    Meltzer, David E.; Thornton, Ronald K.

    2012-06-01

    This Resource Letter provides a guide to the literature on research-based active-learning instruction in physics. These are instructional methods that are based on, assessed by, and validated through research on the teaching and learning of physics. They involve students in their own learning more deeply and more intensely than does traditional instruction, particularly during class time. The instructional methods and supporting body of research reviewed here offer potential for significantly improved learning in comparison to traditional lecture-based methods of college and university physics instruction. We begin with an introduction to the history of active learning in physics in the United States, and then discuss some methods for and outcomes of assessing pedagogical effectiveness. We enumerate and describe common characteristics of successful active-learning instructional strategies in physics. We then discuss a range of methods for introducing active-learning instruction in physics and provide references to those methods for which there is published documentation of student learning gains.

  8. Estimating resource costs of compliance with EU WFD ecological status requirements at the river basin scale

    NASA Astrophysics Data System (ADS)

    Riegels, Niels; Jensen, Roar; Bensasson, Lisa; Banou, Stella; Møller, Flemming; Bauer-Gottwein, Peter

    2011-01-01

    SummaryResource costs of meeting EU WFD ecological status requirements at the river basin scale are estimated by comparing net benefits of water use given ecological status constraints to baseline water use values. Resource costs are interpreted as opportunity costs of water use arising from water scarcity. An optimization approach is used to identify economically efficient ways to meet WFD requirements. The approach is implemented using a river basin simulation model coupled to an economic post-processor; the simulation model and post-processor are run from a central controller that iterates until an allocation is found that maximizes net benefits given WFD requirements. Water use values are estimated for urban/domestic, agricultural, industrial, livestock, and tourism water users. Ecological status is estimated using metrics that relate average monthly river flow volumes to the natural hydrologic regime. Ecological status is only estimated with respect to hydrologic regime; other indicators are ignored in this analysis. The decision variable in the optimization is the price of water, which is used to vary demands using consumer and producer water demand functions. The price-based optimization approach minimizes the number of decision variables in the optimization problem and provides guidance for pricing policies that meet WFD objectives. Results from a real-world application in northern Greece show the suitability of the approach for use in complex, water-stressed basins. The impact of uncertain input values on model outcomes is estimated using the Info-Gap decision analysis framework.

  9. 78 FR 18421 - Information Collection Activities; Household Movers' Disclosure Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-26

    ... Surface Transportation Board Information Collection Activities; Household Movers' Disclosure Requirements... Surface Transportation Board (Board) gives notice that it is requesting from the Office of Management and... Budget, Office of Information and Regulatory Affairs, Attention: Patrick Fuchs, Surface...

  10. Active Learning Techniques Applied to an Interdisciplinary Mineral Resources Course.

    NASA Astrophysics Data System (ADS)

    Aird, H. M.

    2015-12-01

    An interdisciplinary active learning course was introduced at the University of Puget Sound entitled 'Mineral Resources and the Environment'. Various formative assessment and active learning techniques that have been effective in other courses were adapted and implemented to improve student learning, increase retention and broaden knowledge and understanding of course material. This was an elective course targeted towards upper-level undergraduate geology and environmental majors. The course provided an introduction to the mineral resources industry, discussing geological, environmental, societal and economic aspects, legislation and the processes involved in exploration, extraction, processing, reclamation/remediation and recycling of products. Lectures and associated weekly labs were linked in subject matter; relevant readings from the recent scientific literature were assigned and discussed in the second lecture of the week. Peer-based learning was facilitated through weekly reading assignments with peer-led discussions and through group research projects, in addition to in-class exercises such as debates. Writing and research skills were developed through student groups designing, carrying out and reporting on their own semester-long research projects around the lasting effects of the historical Ruston Smelter on the biology and water systems of Tacoma. The writing of their mini grant proposals and final project reports was carried out in stages to allow for feedback before the deadline. Speakers from industry were invited to share their specialist knowledge as guest lecturers, and students were encouraged to interact with them, with a view to employment opportunities. Formative assessment techniques included jigsaw exercises, gallery walks, placemat surveys, think pair share and take-home point summaries. Summative assessment included discussion leadership, exams, homeworks, group projects, in-class exercises, field trips, and pre-discussion reading exercises

  11. Reasoning abstractly about resources

    NASA Technical Reports Server (NTRS)

    Clement, B.; Barrett, A.

    2001-01-01

    r describes a way to schedule high level activities before distributing them across multiple rovers in order to coordinate the resultant use of shared resources regardless of how each rover decides how to perform its activities. We present an algorithm for summarizing the metric resource requirements of an abstract activity based n the resource usages of its potential refinements.

  12. UML activity diagrams in requirements specification of logic controllers

    NASA Astrophysics Data System (ADS)

    Grobelna, Iwona; Grobelny, Michał

    2015-12-01

    Logic controller specification can be prepared using various techniques. One of them is the wide understandable and user-friendly UML language and its activity diagrams. Using formal methods during the design phase increases the assurance that implemented system meets the project requirements. In the approach we use the model checking technique to formally verify a specification against user-defined behavioral requirements. The properties are usually defined as temporal logic formulas. In the paper we propose to use UML activity diagrams in requirements definition and then to formalize them as temporal logic formulas. As a result, UML activity diagrams can be used both for logic controller specification and for requirements definition, what simplifies the specification and verification process.

  13. 48 CFR 801.602-73 - Review requirements for scarce medical specialist contracts and contracts for health-care resources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... scarce medical specialist contracts and contracts for health-care resources. 801.602-73 Section 801.602... Responsibilities 801.602-73 Review requirements for scarce medical specialist contracts and contracts for health-care resources. For contracts to be awarded under the authority of either 38 U.S.C. 7409 or 38...

  14. 33 CFR 155.4045 - Required agreements or contracts with the salvage and marine firefighting resource providers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... with the salvage and marine firefighting resource providers. 155.4045 Section 155.4045 Navigation and... MATERIAL POLLUTION PREVENTION REGULATIONS FOR VESSELS Salvage and Marine Firefighting § 155.4045 Required agreements or contracts with the salvage and marine firefighting resource providers. (a) You may only...

  15. 33 CFR 155.4045 - Required agreements or contracts with the salvage and marine firefighting resource providers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... with the salvage and marine firefighting resource providers. 155.4045 Section 155.4045 Navigation and... MATERIAL POLLUTION PREVENTION REGULATIONS FOR VESSELS Salvage and Marine Firefighting § 155.4045 Required agreements or contracts with the salvage and marine firefighting resource providers. (a) You may only...

  16. Creating the spatial framework for National Aquatic Resource Surveys (NARS): Melding National Aquatic Data Sets with Survey Requirements

    EPA Science Inventory

    The U.S. EPA’s National Aquatic Resource Surveys (NARS) require a consistent spatial representation of the resource target populations being monitored (i.e., rivers and streams, lakes, coastal waters, and wetlands). A sample frame is the GIS representation of this target popula...

  17. 42 CFR 435.220 - Individuals who would meet the income and resource requirements under AFDC if child care costs...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Individuals who would meet the income and resource... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... § 435.220 Individuals who would meet the income and resource requirements under AFDC if child care...

  18. 42 CFR 435.210 - Individuals who meet the income and resource requirements of the cash assistance programs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Individuals who meet the income and resource... & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS... Disabled § 435.210 Individuals who meet the income and resource requirements of the cash...

  19. 42 CFR 436.220 - Individuals who would meet the income and resource requirements under AFDC if child care costs...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Individuals who would meet the income and resource... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL..., Including Pregnant Women § 436.220 Individuals who would meet the income and resource requirements...

  20. 42 CFR 436.210 - Individuals who meet the income and resource requirements of the cash assistance programs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Individuals who meet the income and resource... & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS... Women § 436.210 Individuals who meet the income and resource requirements of the cash...

  1. 42 CFR 435.210 - Individuals who meet the income and resource requirements of the cash assistance programs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Individuals who meet the income and resource... & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS... Individuals who meet the income and resource requirements of the cash assistance programs. The agency...

  2. 42 CFR 435.220 - Individuals who would meet the income and resource requirements under AFDC if child care costs...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Individuals who would meet the income and resource... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... would meet the income and resource requirements under AFDC if child care costs were paid from...

  3. 42 CFR 435.210 - Individuals who meet the income and resource requirements of the cash assistance programs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Individuals who meet the income and resource... & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS... Individuals who meet the income and resource requirements of the cash assistance programs. The agency...

  4. 42 CFR 436.210 - Individuals who meet the income and resource requirements of the cash assistance programs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Individuals who meet the income and resource... & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS... Women § 436.210 Individuals who meet the income and resource requirements of the cash...

  5. 42 CFR 436.220 - Individuals who would meet the income and resource requirements under AFDC if child care costs...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Individuals who would meet the income and resource... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL..., Including Pregnant Women § 436.220 Individuals who would meet the income and resource requirements...

  6. 42 CFR 436.210 - Individuals who meet the income and resource requirements of the cash assistance programs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Individuals who meet the income and resource... & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS... Women § 436.210 Individuals who meet the income and resource requirements of the cash...

  7. 42 CFR 435.210 - Individuals who meet the income and resource requirements of the cash assistance programs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Individuals who meet the income and resource... & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS... Disabled § 435.210 Individuals who meet the income and resource requirements of the cash...

  8. 42 CFR 435.210 - Individuals who meet the income and resource requirements of the cash assistance programs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Individuals who meet the income and resource... & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS... Disabled § 435.210 Individuals who meet the income and resource requirements of the cash...

  9. 42 CFR 436.210 - Individuals who meet the income and resource requirements of the cash assistance programs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Individuals who meet the income and resource... & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS... Women § 436.210 Individuals who meet the income and resource requirements of the cash...

  10. 42 CFR 435.220 - Individuals who would meet the income and resource requirements under AFDC if child care costs...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Individuals who would meet the income and resource... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... § 435.220 Individuals who would meet the income and resource requirements under AFDC if child care...

  11. 42 CFR 436.220 - Individuals who would meet the income and resource requirements under AFDC if child care costs...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Individuals who would meet the income and resource... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL..., Including Pregnant Women § 436.220 Individuals who would meet the income and resource requirements...

  12. 42 CFR 435.220 - Individuals who would meet the income and resource requirements under AFDC if child care costs...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Individuals who would meet the income and resource... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... would meet the income and resource requirements under AFDC if child care costs were paid from...

  13. 42 CFR 436.220 - Individuals who would meet the income and resource requirements under AFDC if child care costs...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Individuals who would meet the income and resource... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL..., Including Pregnant Women § 436.220 Individuals who would meet the income and resource requirements...

  14. 42 CFR 436.210 - Individuals who meet the income and resource requirements of the cash assistance programs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Individuals who meet the income and resource... & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS... Women § 436.210 Individuals who meet the income and resource requirements of the cash...

  15. 42 CFR 436.220 - Individuals who would meet the income and resource requirements under AFDC if child care costs...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Individuals who would meet the income and resource... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL..., Including Pregnant Women § 436.220 Individuals who would meet the income and resource requirements...

  16. 42 CFR 435.220 - Individuals who would meet the income and resource requirements under AFDC if child care costs...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Individuals who would meet the income and resource... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... § 435.220 Individuals who would meet the income and resource requirements under AFDC if child care...

  17. 48 CFR 3004.470 - Security requirements for access to unclassified facilities, Information Technology resources...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... access to unclassified facilities, Information Technology resources, and sensitive information. 3004.470... Technology resources, and sensitive information. ... ACQUISITION REGULATION (HSAR) GENERAL ADMINISTRATIVE MATTERS Safeguarding Classified and Sensitive...

  18. 48 CFR 3004.470 - Security requirements for access to unclassified facilities, Information Technology resources...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... access to unclassified facilities, Information Technology resources, and sensitive information. 3004.470... Technology resources, and sensitive information. ... ACQUISITION REGULATION (HSAR) GENERAL ADMINISTRATIVE MATTERS Safeguarding Classified and Sensitive...

  19. 48 CFR 3004.470 - Security requirements for access to unclassified facilities, Information Technology resources...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... access to unclassified facilities, Information Technology resources, and sensitive information. 3004.470... Technology resources, and sensitive information. ... ACQUISITION REGULATION (HSAR) GENERAL ADMINISTRATIVE MATTERS Safeguarding Classified and Sensitive...

  20. Space Resource Requirements for Future In-Space Propellant Production Depots

    NASA Technical Reports Server (NTRS)

    Smitherman, David; Fikes, John; Roy, Stephanie; Henley, Mark W.; Potter, Seth D.; Howell, Joe T. (Technical Monitor)

    2001-01-01

    In 2000 and 2001 studies were conducted at the NASA Marshall Space Flight Center on the technical requirements and commercial potential for propellant production depots in low Earth orbit (LEO) to support future commercial, NASA, and other Agency missions. Results indicate that propellant production depots appear to be technically feasible given continued technology development, and there is a substantial growing market that depots could support. Systems studies showed that the most expensive part of transferring payloads to geosynchronous orbit (GEO) is the fuel. A cryogenic propellant production and storage depot stationed in LEO could lower the cost of missions to GEO and beyond. Propellant production separates water into hydrogen and oxygen through electrolysis. This process utilizes large amounts of power, therefore a depot derived from advanced space solar power technology was defined. Results indicate that in the coming decades there could be a significant demand for water-based propellants from Earth, moon, or asteroid resources if in-space transfer vehicles (upper stages) transitioned to reusable systems using water based propellants. This type of strategic planning move could create a substantial commercial market for space resources development, and ultimately lead toward significant commercial infrastructure development within the Earth-Moon system.

  1. Optimization-based manufacturing scheduling with multiple resources and setup requirements

    NASA Astrophysics Data System (ADS)

    Chen, Dong; Luh, Peter B.; Thakur, Lakshman S.; Moreno, Jack, Jr.

    1998-10-01

    The increasing demand for on-time delivery and low price forces manufacturer to seek effective schedules to improve coordination of multiple resources and to reduce product internal costs associated with labor, setup and inventory. This study describes the design and implementation of a scheduling system for J. M. Product Inc. whose manufacturing is characterized by the need to simultaneously consider machines and operators while an operator may attend several operations at the same time, and the presence of machines requiring significant setup times. The scheduling problem with these characteristics are typical for many manufacturers, very difficult to be handled, and have not been adequately addressed in the literature. In this study, both machine and operators are modeled as resources with finite capacities to obtain efficient coordination between them, and an operator's time can be shared by several operations at the same time to make full use of the operator. Setups are explicitly modeled following our previous work, with additional penalties on excessive setups to reduce setup costs and avoid possible scraps. An integer formulation with a separable structure is developed to maximize on-time delivery of products, low inventory and small number of setups. Within the Lagrangian relaxation framework, the problem is decomposed into individual subproblems that are effectively solved by using dynamic programming with additional penalties embedded in state transitions. Heuristics is then developed to obtain a feasible schedule following on our previous work with new mechanism to satisfy operator capacity constraints. The method has been implemented using the object-oriented programming language C++ with a user-friendly interface, and numerical testing shows that the method generates high quality schedules in a timely fashion. Through simultaneous consideration of machines and operators, machines and operators are well coordinated to facilitate the smooth flow of

  2. Resource assurance predicts specialist and generalist bee activity in drought

    PubMed Central

    Minckley, Robert L.; Roulston, T'ai H.; Williams, Neal M.

    2013-01-01

    Many short-lived desert organisms remain in diapause during drought. Theoretically, the cues desert species use to continue diapause through drought should differ depending on the availability of critical resources, but the unpredictability and infrequent occurrence of climate extremes and reduced insect activity during such events make empirical tests of this prediction difficult. An intensive study of a diverse bee–plant community through a drought event found that bee specialists of a drought-sensitive host plant were absent in the drought year in contrast to generalist bees and to specialist bees of a drought-insensitive host plant. Different responses of bee species to drought indicate that the diapause cues used by bee species allow them to reliably predict host availability. Species composition of the bee community in drought shifted towards mostly generalist species. However, we predict that more frequent and extended drought, predicted by climate change models for southwest North America, will result in bee communities that are species-poor and dominated by specialist species, as found today in the most arid desert region of North America. PMID:23536593

  3. 10 CFR 63.46 - Particular activities requiring license amendment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Particular activities requiring license amendment. 63.46 Section 63.46 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses License Issuance and Amendment §...

  4. 10 CFR 63.46 - Particular activities requiring license amendment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Particular activities requiring license amendment. 63.46 Section 63.46 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses License Issuance and Amendment §...

  5. 10 CFR 63.46 - Particular activities requiring license amendment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Particular activities requiring license amendment. 63.46 Section 63.46 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses License Issuance and Amendment §...

  6. 10 CFR 63.46 - Particular activities requiring license amendment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Particular activities requiring license amendment. 63.46 Section 63.46 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses License Issuance and Amendment §...

  7. 10 CFR 63.46 - Particular activities requiring license amendment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Particular activities requiring license amendment. 63.46 Section 63.46 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses License Issuance and Amendment §...

  8. 10 CFR 490.507 - Credit activity reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 490.507 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Alternative Fueled Vehicle Credit Program § 490.507 Credit activity reporting requirements. (a) A covered person or fleet applying for allocation of alternative fueled vehicle credits must submit a...

  9. 10 CFR 490.507 - Credit activity reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 490.507 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Alternative Fueled Vehicle Credit Program § 490.507 Credit activity reporting requirements. (a) A covered person or fleet applying for allocation of alternative fueled vehicle credits must submit a...

  10. Requirements for extravehicular activities on the lunar and Martian surfaces

    NASA Technical Reports Server (NTRS)

    Brown, Mariann F.; Schentrup, Susan M.

    1990-01-01

    Basic design reference requirements pertinent to EVA equipment on lunar and martian surfaces are provided. Environmental factors affecting surface EVA are analyzed including gravity, dust, atmospheric conditions, thermal gradients, lightning conditions, and radiation effects, and activities associated with surface EVA are outlined. Environmental and activity effects on EVA equipment are assessed, and emphasis is placed on planetary surface portable life support systems (PLSS), suit development, protection from micrometeoroids, dust, and radiation, food and water supplies, and the extravehicular mobility-unit thermal-control system. Environmental and activity impacts on PLSS design are studied, with focus on base self-sufficiency and reduction in resupply logistics.

  11. Physical Sciences: Curriculum Resources and Activities for School Librarians and Teachers.

    ERIC Educational Resources Information Center

    Bain, Amy; Richer, Janet; Weckman, Janet

    This book provides resources to teachers and librarians for creating thematic units on specific topics targeting grades K-8. Each topic includes key concepts, comprehensive teaching resources, teaching resources (nonfiction children's literature), reading selections (fiction children's literature), science activities, creative writing and art…

  12. The Role of Learned Resourcefulness in Helping Female Undergraduates Deal with Unwanted Sexual Activity

    ERIC Educational Resources Information Center

    Kennett, Deborah J.; Humphreys, Terry P.; Patchell, Meghan

    2009-01-01

    We examined the relationship between learned resourcefulness skills and the manner in which undergraduate heterosexual women handle unwanted sexual advances/activity. Participants consisted of 150 females completing a set of questionnaires assessing general learned resourcefulness, sexual giving-in experience, sexual resourcefulness, sexual…

  13. Earth Sciences: Curriculum Resources and Activities for School Librarians and Teachers.

    ERIC Educational Resources Information Center

    Bain, Amy; Richer, Janet; Weckman, Janet

    This book provides resources to teachers and librarians for creating thematic units on specific topics targeting grades K-8. Each topic includes key concepts, comprehensive teaching resources, teaching resources (nonfiction children's literature), reading selections (fiction children's literature), science activities, creative writing and art…

  14. Life Sciences: Curriculum Resources and Activities for School Librarians and Teachers.

    ERIC Educational Resources Information Center

    Bain, Amy; Richer, Janet; Weckman, Janet

    This book provides resources to teachers and librarians for creating thematic units on specific topics targeting grades K-8. Each topic includes key concepts, comprehensive teaching resources, teaching resources (nonfiction children's literature), reading selections (fiction children's literature), science activities, creative writing and art…

  15. Advanced Marketing 8130. Instructional Areas. Duties and Tasks. Learning Activities. Referenced Resources.

    ERIC Educational Resources Information Center

    Virginia State Dept. of Education, Richmond.

    This resource handbook, which is designed for use by instructors of courses in advanced marketing, consists of a duty/task list with referenced resources, a duty/task list with learning activities, and a list of resources. Included in each list are materials dealing with the following topics: communication in marketing, economics in marketing,…

  16. Using activity-based costing to track resource use in group practices.

    PubMed

    Zeller, T L; Siegel, G; Kaciuba, G; Lau, A H

    1999-09-01

    Research shows that understanding how resources are consumed can help group practices control costs. An American Academy of Orthopaedic Surgeons study used an activity-based costing (ABC) system to measure how resources are consumed in providing medical services. Teams of accounting professors observed 18 diverse orthopedic surgery practices. The researchers identified 17 resource-consuming business processes performed by nonphysician office staff. They measured resource consumption by assigning costs to each process according to how much time is spent on related work activities. When group practices understand how their resources are being consumed, they can reduce costs and optimize revenues by making adjustments in how administrative and clinical staff work. PMID:11066706

  17. MafG Sumoylation Is Required for Active Transcriptional Repression

    PubMed Central

    Motohashi, Hozumi; Katsuoka, Fumiki; Miyoshi, Chika; Uchimura, Yasuhiro; Saitoh, Hisato; Francastel, Claire; Engel, James Douglas; Yamamoto, Masayuki

    2006-01-01

    A straightforward mechanism for eliciting transcriptional repression would be to simply block the DNA binding site for activators. Such passive repression is often mediated by transcription factors that lack an intrinsic repressor activity. MafG is a bidirectional regulator of transcription, a repressor in its homodimeric state but an activator when heterodimerized with p45. Here, we report that MafG is conjugated to SUMO-2/3 in vivo. To clarify the possible physiological role(s) for sumoylation in regulating MafG activity, we evaluated mutant and wild-type MafG in transgenic mice and cultured cells. Whereas sumoylation-deficient MafG activated p45-dependent transcription normally and did not affect heterodimer activity, repression by the sumoylation-deficient MafG mutant was severely compromised in vivo. Furthermore, the SUMO-dependent repression activity of MafG was sensitive to histone deacetylase inhibition. Thus, repression by MafG is not achieved through simple passive repression by competing for the activator binding site but requires sumoylation, which then mediates transcriptional repression through recruitment of a repressor complex containing histone deacetylase activity. PMID:16738329

  18. Macrophages require different nucleoside transport systems for proliferation and activation.

    PubMed

    Soler, C; García-Manteiga, J; Valdés, R; Xaus, J; Comalada, M; Casado, F J; Pastor-Anglada, M; Celada, A; Felipe, A

    2001-09-01

    To evaluate the mechanisms involved in macrophage proliferation and activation, we studied the regulation of the nucleoside transport systems. In murine bone marrow-derived macrophages, the nucleosides required for DNA and RNA synthesis are recruited from the extracellular medium. M-CSF induced macrophage proliferation and DNA and RNA synthesis, whereas interferon gamma (IFN-gamma) led to activation, blocked proliferation, and induced only RNA synthesis. Macrophages express at least the concentrative systems N1 and N2 (CNT2 and CNT1 genes, respectively) and the equilibrative systems es and ei (ENT1 and ENT2 genes, respectively). Incubation with M-CSF only up-regulated the equilibrative system es. Inhibition of this transport system blocked M-CSF-dependent proliferation. Treatment with IFN-gamma only induced the concentrative N1 and N2 systems. IFN-gamma also down-regulated the increased expression of the es equilibrative system induced by M-CSF. Thus, macrophage proliferation and activation require selective regulation of nucleoside transporters and may respond to specific requirements for DNA and RNA synthesis. This report also shows that the nucleoside transporters are critical for macrophage proliferation and activation. PMID:11532978

  19. Time required for motor activity in lucid dreams.

    PubMed

    Erlacher, Daniel; Schredl, Michael

    2004-12-01

    The present study investigated the relationship between the time required for specific tasks (counting and performing squats) in lucid dreams and in the waking state. Five proficient lucid dreamers (26-34 yr. old, M=29.8, SD=3.0; one woman and four men) participated. Analysis showed that the time needed for counting in a lucid dream is comparable to the time needed for counting in wakefulness, but motor activities required more time in lucid dreams than in the waking state. PMID:15739850

  20. TERSSE: Definition of the Total Earth Resources System for the Shuttle Era. Volume 5: Detailed system requirements: Two case studies

    NASA Technical Reports Server (NTRS)

    1974-01-01

    Major resource management missions to be performed by the TERSSE are examined in order to develop an understanding of the form and function of a system designed to perform an operational mission. Factors discussed include: resource manager (user) functions, methods of performing their function, the information flows and information requirements embodied in their function, and the characteristics of the observation system which assists in the management of the resource involved. The missions selected for study are: world crop survey and land resources management. These missions are found to represent opposite ends of the TERSSE spectrum and to support the conclusion that different missions require different systems and must be analyzed in detail to permit proper system development decisions.

  1. Environmental Resources in Maintenance of Physical Activity 6 Months Following Cardiac Rehabilitation.

    PubMed

    Perez, Adriana; Fleury, Julie; Belyea, Michael

    2016-08-01

    This study examined differences in weekly time spent in physical activity by level of perceived environmental resources, 6 months following graduation from cardiac rehabilitation. A descriptive, longitudinal design used standardized measures to evaluate perceived environmental resources and physical activity levels. Repeated measures analysis of variance was used to examine mean differences in weekly time spent in physical activity by level of perceived environmental resources. Adults 51 to 86 years old (N = 150) diagnosed with coronary heart disease were included. There was a significant change over time in physical activity as measured by minutes per week, F(2, 148) = 7.915, p = .001, where activity increased between baseline and 3 months, and then dropped slightly at 6 months. This change over time differed by the level of perceived neighborhood resources, F(2, 148) = 3.545, p = .032. Home and neighborhood resources may positively influence physical activity maintenance following cardiac rehabilitation. PMID:26826141

  2. Soluble Epoxide Hydrolase Dimerization Is Required for Hydrolase Activity*

    PubMed Central

    Nelson, Jonathan W.; Subrahmanyan, Rishi M.; Summers, Sol A.; Xiao, Xiangshu; Alkayed, Nabil J.

    2013-01-01

    Soluble epoxide hydrolase (sEH) plays a key role in the metabolic conversion of the protective eicosanoid 14,15-epoxyeicosatrienoic acid to 14,15-dihydroxyeicosatrienoic acid. Accordingly, inhibition of sEH hydrolase activity has been shown to be beneficial in multiple models of cardiovascular diseases, thus identifying sEH as a valuable therapeutic target. Recently, a common human polymorphism (R287Q) was identified that reduces sEH hydrolase activity and is localized to the dimerization interface of the protein, suggesting a relationship between sEH dimerization and activity. To directly test the hypothesis that dimerization is essential for the proper function of sEH, we generated mutations within the sEH protein that would either disrupt or stabilize dimerization. We quantified the dimerization state of each mutant using a split firefly luciferase protein fragment-assisted complementation system. The hydrolase activity of each mutant was determined using a fluorescence-based substrate conversion assay. We found that mutations that disrupted dimerization also eliminated hydrolase enzymatic activity. In contrast, a mutation that stabilized dimerization restored hydrolase activity. Finally, we investigated the kinetics of sEH dimerization and found that the human R287Q polymorphism was metastable and capable of swapping dimer partners faster than the WT enzyme. These results indicate that dimerization is required for sEH hydrolase activity. Disrupting sEH dimerization may therefore serve as a novel therapeutic strategy for reducing sEH hydrolase activity. PMID:23362272

  3. Soluble epoxide hydrolase dimerization is required for hydrolase activity.

    PubMed

    Nelson, Jonathan W; Subrahmanyan, Rishi M; Summers, Sol A; Xiao, Xiangshu; Alkayed, Nabil J

    2013-03-15

    Soluble epoxide hydrolase (sEH) plays a key role in the metabolic conversion of the protective eicosanoid 14,15-epoxyeicosatrienoic acid to 14,15-dihydroxyeicosatrienoic acid. Accordingly, inhibition of sEH hydrolase activity has been shown to be beneficial in multiple models of cardiovascular diseases, thus identifying sEH as a valuable therapeutic target. Recently, a common human polymorphism (R287Q) was identified that reduces sEH hydrolase activity and is localized to the dimerization interface of the protein, suggesting a relationship between sEH dimerization and activity. To directly test the hypothesis that dimerization is essential for the proper function of sEH, we generated mutations within the sEH protein that would either disrupt or stabilize dimerization. We quantified the dimerization state of each mutant using a split firefly luciferase protein fragment-assisted complementation system. The hydrolase activity of each mutant was determined using a fluorescence-based substrate conversion assay. We found that mutations that disrupted dimerization also eliminated hydrolase enzymatic activity. In contrast, a mutation that stabilized dimerization restored hydrolase activity. Finally, we investigated the kinetics of sEH dimerization and found that the human R287Q polymorphism was metastable and capable of swapping dimer partners faster than the WT enzyme. These results indicate that dimerization is required for sEH hydrolase activity. Disrupting sEH dimerization may therefore serve as a novel therapeutic strategy for reducing sEH hydrolase activity. PMID:23362272

  4. Structural Requirements for the Procoagulant Activity of Nucleic Acids

    PubMed Central

    Gansler, Julia; Jaax, Miriam; Leiting, Silke; Appel, Bettina; Greinacher, Andreas; Fischer, Silvia; Preissner, Klaus T.

    2012-01-01

    Nucleic acids, especially extracellular RNA, are exposed following tissue- or vessel damage and have previously been shown to activate the intrinsic blood coagulation pathway in vitro and in vivo. Yet, no information on structural requirements for the procoagulant activity of nucleic acids is available. A comparison of linear and hairpin-forming RNA- and DNA-oligomers revealed that all tested oligomers forming a stable hairpin structure were protected from degradation in human plasma. In contrast to linear nucleic acids, hairpin forming compounds demonstrated highest procoagulant activities based on the analysis of clotting time in human plasma and in a prekallikrein activation assay. Moreover, the procoagulant activities of the DNA-oligomers correlated well with their binding affinity to high molecular weight kininogen, whereas the binding affinity of all tested oligomers to prekallikrein was low. Furthermore, four DNA-aptamers directed against thrombin, activated protein C, vascular endothelial growth factor and nucleolin as well as the naturally occurring small nucleolar RNA U6snRNA were identified as effective cofactors for prekallikrein auto-activation. Together, we conclude that hairpin-forming nucleic acids are most effective in promoting procoagulant activities, largely mediated by their specific binding to kininogen. Thus, in vivo application of therapeutic nucleic acids like aptamers might have undesired prothrombotic or proinflammatory side effects. PMID:23226277

  5. Resources.

    ERIC Educational Resources Information Center

    Stewart, John; MacDonald, Ian

    1980-01-01

    Presents a guide to resources on television drama available to teachers for classroom use in television curriculum. Lists American and British television drama videorecordings of both series and individual presentations and offers a bibliography of "one-off" single fiction plays produced for British television. (JMF)

  6. Data Handling for EO-Missions with High Data Rates Requiring Low Resources

    NASA Astrophysics Data System (ADS)

    Penné, B.; Tobehn, C.; Rathje, R.; Michalik, H.

    2008-08-01

    High spatial or spectral resolution optical or SAR Earth observation missions set requirements for high data rate and volume. The limited downlink bandwidth on the other hand can be overcome by recently new technolo- gies within the transmitter technology on one side and the data pre-processing and/or compression on-board on the other side. This advanced architecture for space- borne high speed payload data handling system (PDHS) is an important element to process more data with even smaller system to gain significant the overall system effectiveness. The PDHS chain introduces the advantages of channel link and IEEE 1355 space wire standards to provide scaleable redundancy and performance. The modules of the chain like on-board data processing (LEON proces- sor) feature data pre-processing, compression, and trun- cation of data to the area of interest as well as data stor- age, data formatting (CCSDS), data encryption and downlink. The system comprises also the complete ground test equipment for verification of the PDHS as stand-alone units, at subsystem level and for complete system tests during satellite AIV. The OHB-System experience gained from development of PDHS within three projects MSRS, KOMPSAT II and SAR-Lupe, form the baseline of our PDHS, that reaches several Gbit/s input rate and an output rate of about 500 up to 1000 Mbit/s using dual polarisation techniques at X-Band at considerable low resources.

  7. 43 CFR 24.4 - Resource management and public activities on Federal lands.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Resource management and public activities on Federal lands. 24.4 Section 24.4 Public Lands: Interior Office of the Secretary of the Interior DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.4 Resource management and public activities on Federal lands....

  8. The effects of task difficulty and resource requirements on attention strategies

    NASA Technical Reports Server (NTRS)

    King, Teresa

    1991-01-01

    The patterns of attention strategies for task difficulty/resource tasks for which experimental results are presented and analyzed support the hypothesis that subjects may adopt an alternating (rather than concurrent one) when compelled to do so by either the size or the complexity of a visual display. According to the multiple resource model, if subjects had been performing the two tasks concurrently, the cost of this strategy would have been shown by a decrement in the spatial format, rather than the verbal format, due to competition for the same resource. Subjects may apply different strategies as a function of task difficulty and/or resource demand.

  9. Engaging the Families of ELLs: Ideas, Resources, and Activities

    ERIC Educational Resources Information Center

    Rubin, Renee; Abrego, Michelle H.; Sutterby, John A.

    2012-01-01

    Learn how to involve the diverse families of English language learners with the effective, practical approaches in this book. This must-have resource for teachers and school leaders is packed with fresh ideas geared toward building a partnership between school communities and ELL families. The authors begin each chapter with realistic scenarios…

  10. Options and legal requirements for national and regional animal genetic resources collections

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The contraction of animal genetic resources on a global scale has motivated countries to establish gene banks as a mechanism to conserve national resources. Gene banks should establish a set of policies that insure they are complying with national laws. The two primary areas of consideration are ho...

  11. Instantaneous Active and Nonactive Power Control of Distributed Energy Resources with Current Limiter

    SciTech Connect

    Xu, Yan; Li, Huijuan; Rizy, D Tom; Li, Fangxing; Kueck, John D

    2010-01-01

    Abstract -- Distributed energy resources (DER) with a power electronics inverter interface can provide both active power and nonactive power simultaneously and independently. A decoupled control algorithm of active power and nonactive power is developed based on the instantaneous active power and nonactive power theory. A current limiter is combined to the control algorithm, and it ensures that the inverter is not overloaded. During the normal system operation, the active power has higher priority over the nonactive power so that the energy from a DER can be fully transferred to the grid. Within the inverter s capability, nonactive power is provided to the grid as required. With this control algorithm, the inverter s capabilities are taken full advantage at all times, both in terms of functionality as well as making use of its full KVA rating. Through the algorithm, the inverter s active power and nonactive power are controlled directly, simultaneously, and independently. Several experimental results fully demonstrate the validity and effectiveness of this new control algorithm. As evidenced by the fast dynamic response that results, a DER system with the control algorithm can provide full services to the grid in both steady state and during transient events.

  12. The Green Revolution in Transportation. Resource Recovery. Technology Learning Activities.

    ERIC Educational Resources Information Center

    Technology Teacher, 1991

    1991-01-01

    These two learning activities provide context, objectives, list of materials, student activity, and evaluation criteria. The first involves an automotive class in developing a model alternative fueled vehicle, and the second involves the design of a useful recyclable product. (JOW)

  13. 43 CFR 3275.18 - May BLM require me to test for byproducts associated with geothermal resource production?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false May BLM require me to test for byproducts associated with geothermal resource production? 3275.18 Section 3275.18 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) GEOTHERMAL...

  14. 40 CFR Appendix E to Part 112 - Determination and Evaluation of Required Response Resources for Facility Response Plans

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 23 2013-07-01 2013-07-01 false Determination and Evaluation of Required Response Resources for Facility Response Plans E Appendix E to Part 112 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS OIL POLLUTION PREVENTION Pt. 112, App. E Appendix E to Part 112—Determination...

  15. 40 CFR Appendix E to Part 112 - Determination and Evaluation of Required Response Resources for Facility Response Plans

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Determination and Evaluation of Required Response Resources for Facility Response Plans E Appendix E to Part 112 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS OIL POLLUTION PREVENTION Pt. 112, App. E Appendix E to Part 112—Determination...

  16. 40 CFR Appendix E to Part 112 - Determination and Evaluation of Required Response Resources for Facility Response Plans

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 22 2011-07-01 2011-07-01 false Determination and Evaluation of Required Response Resources for Facility Response Plans E Appendix E to Part 112 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS OIL POLLUTION PREVENTION Pt. 112, App. E Appendix E to Part 112—Determination...

  17. Adequacy of Material Resources Required for Effective Implementation of Upper Basic Education Business Studies Curriculum in Nigeria

    ERIC Educational Resources Information Center

    Okoli, B. E.; Okorie, Ogbonnaya

    2015-01-01

    This work is a descriptive survey of the adequacy of the material resources required for effective implementation of upper basic education business studies curriculum in Ebonyi State. Two research questions and two hypotheses guided the study. The entire population of two hundred and forty-one (241) business studies teachers were used for the…

  18. 20 CFR 665.330 - Are the NAFTA-TAA program requirements for rapid response also required activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Are the NAFTA-TAA program requirements for rapid response also required activities? 665.330 Section 665.330 Employees' Benefits EMPLOYMENT AND... WORKFORCE INVESTMENT ACT Rapid Response Activities § 665.330 Are the NAFTA-TAA program requirements...

  19. Advanced extravehicular activity systems requirements definition study. Phase 2: Extravehicular activity at a lunar base

    NASA Technical Reports Server (NTRS)

    Neal, Valerie; Shields, Nicholas, Jr.; Carr, Gerald P.; Pogue, William; Schmitt, Harrison H.; Schulze, Arthur E.

    1988-01-01

    The focus is on Extravehicular Activity (EVA) systems requirements definition for an advanced space mission: remote-from-main base EVA on the Moon. The lunar environment, biomedical considerations, appropriate hardware design criteria, hardware and interface requirements, and key technical issues for advanced lunar EVA were examined. Six remote EVA scenarios (three nominal operations and three contingency situations) were developed in considerable detail.

  20. RNA helicase A is not required for RISC activity.

    PubMed

    Liang, Xue-Hai; Crooke, Stanley T

    2013-10-01

    It has been shown that siRNAs can compete with each other or with endogenous miRNAs for RISC components. This competition may complicate the interpretations of phenotypes observed through siRNA-mediated knockdown of genes, especially those genes implicated in the RISC pathway. In this study, we re-examined the function of RNA helicase A (RHA), which has been previously proposed to function in RISC loading based on siRNA-mediated knockdown studies. Here we show that reduced RISC activity or loading of siRNAs was observed only in cells depleted of RHA using siRNA, but not using RNaseH-dependent antisense oligonucleotides (ASOs), suggesting that the impaired RISC function stems from the competition between pre-existing and newly transfected siRNAs, but not from reduction of the RHA protein. This view is further supported by the findings that cells depleted of a control protein, NCL1, using siRNA, but not ASO, exhibited similar defects on the loading and activity of a subsequently transfected siRNA. Transfection of RHA or NCL1 siRNAs, but not ASOs, reduced the levels of endogenous miRNAs, suggesting a competition mechanism. As a positive control, we showed that reduction of MOV10 by either siRNA or ASO decreased siRNA activity, confirming its role in RISC function. Together, our results indicate that RHA is not required for RISC activity or loading, and suggest that proper controls are required when using siRNAs to functionalize genes to avoid competition effects. PMID:23895878

  1. Protocols to determine pollination requirements and optimal pollinators for plant genetic resource regeneration

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Guidelines have been established for the maintenance of plant genetic resource collections, including seed regeneration. When carefully conducted, regeneration is a key tool in germplasm conservation, helping reduce the negative effects of genetic erosion. However, inadequate knowledge of basic p...

  2. Image data processing system requirements study. Volume 1: Analysis. [for Earth Resources Survey Program

    NASA Technical Reports Server (NTRS)

    Honikman, T.; Mcmahon, E.; Miller, E.; Pietrzak, L.; Yorsz, W.

    1973-01-01

    Digital image processing, image recorders, high-density digital data recorders, and data system element processing for use in an Earth Resources Survey image data processing system are studied. Loading to various ERS systems is also estimated by simulation.

  3. Preconstruction schedules, costs, and permit requirements for electric power generating resources in the Pacific Northwest

    SciTech Connect

    Hendrickson, P.L.; Smith, S.A.; Thurman, A.G.; Watts, R.L.; Weakley, S.A.

    1990-07-01

    This report was prepared for the Generation Programs Branch, Office of Energy Resources, Bonneville Power Administration (BPA). The principal objective of the report is to assemble in one document preconstruction cost, schedule, and permit information for twelve specific generating resources. The report is one of many documents that provide background information for BPA's Resource Program, which is designed to identify the type and amount of new resources that BPA may have to add over the next twenty years to maintain an adequate and reliable electric power supply in the Pacific Northwest. A predecessor to this report is a 1982 report prepared by the Pacific Northwest Laboratory (PNL) for the Northwest Power Planning Council (the Council''). The 1982 report had a similar, but not identical, content and format. 306 refs., 14 figs., 22 tabs.

  4. Planetary science and resource utilization at a lunar outpost - Chemical analytical facility requirements

    NASA Technical Reports Server (NTRS)

    Taylor, Lawrence A.

    1992-01-01

    Unresolved issues of lunar geology are reviewed and the role of a lunar outpost in helping to address them is considered. Plans for in situ resource utilization of lunar materials are examined. Concepts for a lunar outpost are described.

  5. Active prospective control is required for effective sensorimotor learning.

    PubMed

    Snapp-Childs, Winona; Casserly, Elizabeth; Mon-Williams, Mark; Bingham, Geoffrey P

    2013-01-01

    Passive modeling of movements is often used in movement therapy to overcome disabilities caused by stroke or other disorders (e.g. Developmental Coordination Disorder or Cerebral Palsy). Either a therapist or, recently, a specially designed robot moves or guides the limb passively through the movement to be trained. In contrast, action theory has long suggested that effective skill acquisition requires movements to be actively generated. Is this true? In view of the former, we explicitly tested the latter. Previously, a method was developed that allows children with Developmental Coordination Disorder to produce effective movements actively, so as to improve manual performance to match that of typically developing children. In the current study, we tested practice using such active movements as compared to practice using passive movement. The passive movement employed, namely haptic tracking, provided a strong test of the comparison, one that showed that the mere inaction of the muscles is not the problem. Instead, lack of prospective control was. The result was no effective learning with passive movement while active practice with prospective control yielded significant improvements in performance. PMID:24194891

  6. Active Prospective Control Is Required for Effective Sensorimotor Learning

    PubMed Central

    Snapp-Childs, Winona; Casserly, Elizabeth; Mon-Williams, Mark; Bingham, Geoffrey P.

    2013-01-01

    Passive modeling of movements is often used in movement therapy to overcome disabilities caused by stroke or other disorders (e.g. Developmental Coordination Disorder or Cerebral Palsy). Either a therapist or, recently, a specially designed robot moves or guides the limb passively through the movement to be trained. In contrast, action theory has long suggested that effective skill acquisition requires movements to be actively generated. Is this true? In view of the former, we explicitly tested the latter. Previously, a method was developed that allows children with Developmental Coordination Disorder to produce effective movements actively, so as to improve manual performance to match that of typically developing children. In the current study, we tested practice using such active movements as compared to practice using passive movement. The passive movement employed, namely haptic tracking, provided a strong test of the comparison, one that showed that the mere inaction of the muscles is not the problem. Instead, lack of prospective control was. The result was no effective learning with passive movement while active practice with prospective control yielded significant improvements in performance. PMID:24194891

  7. Invaders do not require high resource levels to maintain physiological advantages in a temperate deciduous forest.

    PubMed

    Heberling, J Mason; Fridley, Jason D

    2016-04-01

    Non-native, invasive plants are commonly typified by trait strategies associated with high resource demands and plant invasions are often thought to be dependent upon site resource availability or disturbance. However, the invasion of shade-tolerant woody species into deciduous forests of the Eastern United States seems to contradict such generalization, as growth in this ecosystem is strongly constrained by light and, secondarily, nutrient stress. In a factorial manipulation of light and soil nitrogen availability, we established an experimental resource gradient in a secondary deciduous forest to test whether three common, woody, invasive species displayed increased metabolic performance and biomass production compared to six co-occurring woody native species, and whether these predicted differences depend upon resource supply. Using hierarchical Bayesian models of photosynthesis that included leaf trait effects, we found that invasive species exhibited functional strategies associated with higher rates of carbon gain. Further, invader metabolic and growth-related attributes were more responsive to increasing light availability than those of natives, but did not fall below average native responses even in low light. Surprisingly, neither group showed direct trait or growth responses to soil N additions. However, invasive species showed increased photosynthetic nitrogen use efficiencies with decreasing N availability, while that of natives remained constant. Although invader advantage over natives was amplified in higher resource conditions in this forest, our results indicate that some invasive species can maintain physiological advantages over co-occurring natives regardless of resource conditions. PMID:27220204

  8. Give me a better break: Choosing workday break activities to maximize resource recovery.

    PubMed

    Hunter, Emily M; Wu, Cindy

    2016-02-01

    Surprisingly little research investigates employee breaks at work, and even less research provides prescriptive suggestions for better workday breaks in terms of when, where, and how break activities are most beneficial. Based on the effort-recovery model and using experience sampling methodology, we examined the characteristics of employee workday breaks with 95 employees across 5 workdays. In addition, we examined resources as a mediator between break characteristics and well-being. Multilevel analysis results indicated that activities that were preferred and earlier in the work shift related to more resource recovery following the break. We also found that resources mediated the influence of preferred break activities and time of break on health symptoms and that resource recovery benefited person-level outcomes of emotional exhaustion, job satisfaction, and organizational citizenship behavior. Finally, break length interacted with the number of breaks per day such that longer breaks and frequent short breaks were associated with more resources than infrequent short breaks. PMID:26375961

  9. Validating Vegetable Production Unit (VPU) Plants, Protocols, Procedures and Requirements (P3R) using Currently Existing Flight Resources

    NASA Technical Reports Server (NTRS)

    Bingham, Gail; Bates, Scott; Bugbee, Bruce; Garland, Jay; Podolski, Igor; Levinskikh, Rita; Sychev, Vladimir; Gushin, Vadim

    2009-01-01

    Validating Vegetable Production Unit (VPU) Plants, Protocols, Procedures and Requirements (P3R) Using Currently Existing Flight Resources (Lada-VPU-P3R) is a study to advance the technology required for plant growth in microgravity and to research related food safety issues. Lada-VPU-P3R also investigates the non-nutritional value to the flight crew of developing plants on-orbit. The Lada-VPU-P3R uses the Lada hardware on the ISS and falls under a cooperative agreement between National Aeronautics and Space Administration (NASA) and the Russian Federal Space Association (FSA). Research Summary: Validating Vegetable Production Unit (VPU) Plants, Protocols, Procedures and Requirements (P3R) Using Currently Existing Flight Resources (Lada-VPU-P3R) will optimize hardware and

  10. 75 FR 27575 - Agency Information Collection Activities: State Water Resources Research Institute Program Annual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-17

    ... notice (74 FR 68860) announcing that we would submit this ICR to OMB for approval and soliciting comments... Geological Survey Agency Information Collection Activities: State Water Resources Research Institute Program... Water Resources Research Act of 1984, as amended (42 U.S.C. 10301 et seq.), authorizes a water...

  11. 34 CFR 656.3 - What activities define a comprehensive or undergraduate National Resource Center?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false What activities define a comprehensive or undergraduate National Resource Center? 656.3 Section 656.3 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION NATIONAL RESOURCE CENTERS PROGRAM FOR FOREIGN LANGUAGE AND...

  12. 34 CFR 656.3 - What activities define a comprehensive or undergraduate National Resource Center?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false What activities define a comprehensive or undergraduate National Resource Center? 656.3 Section 656.3 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION NATIONAL RESOURCE CENTERS PROGRAM FOR FOREIGN LANGUAGE AND...

  13. 77 FR 74517 - Agency Information Collection Activities: Comment Request; Education and Human Resources Project...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-14

    ... the second notice for public comment; the first was published in the Federal Register at 77 FR 33774... FOUNDATION Agency Information Collection Activities: Comment Request; Education and Human Resources Project...: Education and Human Resources Program Monitoring Clearance. OMB Approval Number: 3145-NEW. Type of...

  14. Schwann cell myelination requires integration of laminin activities.

    PubMed

    McKee, Karen K; Yang, Dong-Hua; Patel, Rajesh; Chen, Zu-Lin; Strickland, Sidney; Takagi, Junichi; Sekiguchi, Kiyotoshi; Yurchenco, Peter D

    2012-10-01

    Laminins promote early stages of peripheral nerve myelination by assembling basement membranes (BMs) on Schwann cell surfaces, leading to activation of β1 integrins and other receptors. The BM composition, structural bonds and ligands needed to mediate this process, however, are not well understood. Mice hypomorphic for laminin γ1-subunit expression that assembled endoneurial BMs with reduced component density exhibited an axonal sorting defect with amyelination but normal Schwann cell proliferation, the latter unlike the null. To identify the basis for this, and to dissect participating laminin interactions, LAMC1 gene-inactivated dorsal root ganglia were treated with recombinant laminin-211 and -111 lacking different architecture-forming and receptor-binding activities, to induce myelination. Myelin-wrapping of axons by Schwann cells was found to require higher laminin concentrations than either proliferation or axonal ensheathment. Laminins that were unable to polymerize through deletions that removed critical N-terminal (LN) domains, or that lacked cell-adhesive globular (LG) domains, caused reduced BMs and almost no myelination. Laminins engineered to bind weakly to α6β1 and/or α7β1 integrins through their LG domains, even though they could effectively assemble BMs, decreased myelination. Proliferation depended upon both integrin binding to LG domains and polymerization. Collectively these findings reveal that laminins integrate scaffold-forming and cell-adhesion activities to assemble an endoneurial BM, with myelination and proliferation requiring additional α6β1/α7β1-laminin LG domain interactions, and that a high BM ligand/structural density is needed for efficient myelination. PMID:22767514

  15. Activation of oligodendroglial Stat3 is required for efficient remyelination

    PubMed Central

    Steelman, Andrew J.; Zhou, Yun; Koit, Hisami; Kim, SunJa; Payne, H. Ross; Lu, Q. Richard; Li, Jianrong

    2016-01-01

    Multiple sclerosis is the most prevalent demyelinating disease of the central nervous system (CNS) and is histologically characterized by perivascular demyelination as well as neurodegeneration. While the degree of axonal damage is correlated with clinical disability, it is believed that remyelination can protect axons from degeneration and slow disease progression. Therefore, understanding the intricacies associated with myelination and remyelination may lead to therapeutics that can enhance the remyelination process and slow axon degeneration and loss of function. Ciliary neurotrophic factor (CNTF) family cytokines such as leukemia inhibitory factor (LIF) and interleukin11(IL-11) are known to promote oligodendrocyte maturation and remyelination in experimental models of demyelination. Because CNTF family member binding to the gp 130 receptor results in activation of the JAK2/Stat3 pathway we investigated the necessity of oligodendroglial Stat3 in transducing the signal required for myelination and remyelination. We found that Stat3 activation in the CNS coincides with myelination during development. Stimulation of oligodendrocyte precursor cells (OPCs) with CNTF or LIF promoted OPC survival and final differentiation, which was completely abolished by pharmacologic blockade of Stat3 activation with JAK2 inhibitor. Similarly, genetic ablation of Stat3 in oligodendrocyte lineage cells prevented CNTF-induced OPC differentiation in culture. In vivo, while oligodendroglial Stat3 signaling appears to be dispensable for developmental CNS myelination, it is required for oligodendrocyte regeneration and efficient remyelination after toxin-induced focal demyelination in the adult brain. Our data suggest a critical function for oligodendroglial Stat3 signaling in myelin repair. PMID:27060559

  16. Activation of oligodendroglial Stat3 is required for efficient remyelination.

    PubMed

    Steelman, Andrew J; Zhou, Yun; Koito, Hisami; Kim, SunJa; Payne, H Ross; Lu, Q Richard; Li, Jianrong

    2016-07-01

    Multiple sclerosis is the most prevalent demyelinating disease of the central nervous system (CNS) and is histologically characterized by perivascular demyelination as well as neurodegeneration. While the degree of axonal damage is correlated with clinical disability, it is believed that remyelination can protect axons from degeneration and slow disease progression. Therefore, understanding the intricacies associated with myelination and remyelination may lead to therapeutics that can enhance the remyelination process and slow axon degeneration and loss of function. Ciliary neurotrophic factor (CNTF) family cytokines such as leukemia inhibitory factor (LIF) and interleukin 11 (IL-11) are known to promote oligodendrocyte maturation and remyelination in experimental models of demyelination. Because CNTF family member binding to the gp130 receptor results in activation of the JAK2/Stat3 pathway we investigated the necessity of oligodendroglial Stat3 in transducing the signal required for myelination and remyelination. We found that Stat3 activation in the CNS coincides with myelination during development. Stimulation of oligodendrocyte precursor cells (OPCs) with CNTF or LIF promoted OPC survival and final differentiation, which was completely abolished by pharmacologic blockade of Stat3 activation with JAK2 inhibitor. Similarly, genetic ablation of Stat3 in oligodendrocyte lineage cells prevented CNTF-induced OPC differentiation in culture. In vivo, while oligodendroglial Stat3 signaling appears to be dispensable for developmental CNS myelination, it is required for oligodendrocyte regeneration and efficient remyelination after toxin-induced focal demyelination in the adult brain. Our data suggest a critical function for oligodendroglial Stat3 signaling in myelin repair. PMID:27060559

  17. Measuring Reading Activity: An Inventory. Instructional Resource No. 4.

    ERIC Educational Resources Information Center

    Guthrie, John T.; And Others

    Noting that the amount of reading students do is related to their reading achievement, this booklet presents an instrument designed to measure the amount and breadth of students' reading in and out of school. The first part of the booklet discusses the Reading Activity Inventory (RAI) and how it differs from other reading activity measures, uses…

  18. Photosensitization is required for antiretroviral activity of hypericin

    NASA Astrophysics Data System (ADS)

    Carpenter, Susan; Tossberg, John; Kraus, George A.

    1991-06-01

    In a seminal series of papers, Meruelo and co-workers have described the potent antiretroviral effect of hypericin. Interestingly, hypericin was found to inhibit not only the production of infectious virus from chronically infected cells, but was also shown to directly inhibit reverse transcriptase activity of mature virions. The effect of hypericin on cells chronically infected with equine infectious anemia virus (EIAV), a retrovirus genetically related to HIV, is demonstrated. At concentrations of 10 (mu) g/ml, hypericin reduced production of infectious EIAV by 99.99 without causing obvious cytopathic effects. Interestingly, the results indicated that the antiretroviral activity of hypericin was wholly dependent on the presence of light. No decrease in viral infectivity was observed when hypericin and virus were incubated in the dark. Moreover, it appeared that light was an absolute requirement for the antiviral activity, as even high concentrations of hypericin (10 (mu) g/ml) were unable to reduce infectivity of as few as 100 infectious virions.

  19. Activated carbon fibers and engineered forms from renewable resources

    DOEpatents

    Baker, Frederick S

    2013-02-19

    A method of producing activated carbon fibers (ACFs) includes the steps of providing a natural carbonaceous precursor fiber material, blending the carbonaceous precursor material with a chemical activation agent to form chemical agent-impregnated precursor fibers, spinning the chemical agent-impregnated precursor material into fibers, and thermally treating the chemical agent-impregnated precursor fibers. The carbonaceous precursor material is both carbonized and activated to form ACFs in a single step. The method produces ACFs exclusive of a step to isolate an intermediate carbon fiber.

  20. Activated carbon fibers and engineered forms from renewable resources

    DOEpatents

    Baker, Frederick S.

    2010-06-01

    A method of producing activated carbon fibers (ACFs) includes the steps of providing a natural carbonaceous precursor fiber material, blending the carbonaceous precursor material with a chemical activation agent to form chemical agent-impregnated precursor fibers, spinning the chemical agent-impregnated precursor material into fibers, and thermally treating the chemical agent-impregnated precursor fibers. The carbonaceous precursor material is both carbonized and activated to form ACFs in a single step. The method produces ACFs exclusive of a step to isolate an intermediate carbon fiber.

  1. A summary of activities of the Earth Resources Laboratory at the Mississippi Test Facility during 1971

    NASA Technical Reports Server (NTRS)

    Piland, R. O.

    1972-01-01

    First year activities at the NASA Earth Resources Laboratory are reviewed. Covered are: (1) personnel; (2) organization; (3) technical equipment capabilities; (4) University programs; (5) agency relationships; (6) minor projects; (7) technical program; and (8) 1971 reports and products.

  2. 78 FR 23233 - Agency Information Collection Activities; Comment Request; IEPS International Resource...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF EDUCATION Agency Information Collection Activities; Comment Request; IEPS International Resource Information System (IRIS) AGENCY: Office of Postsecondary Education (OPE), Department of Education (ED). ACTION:...

  3. Urban school leadership for elementary science instruction: Identifying and activating resources in an undervalued school subject

    NASA Astrophysics Data System (ADS)

    Spillane, James P.; Diamond, John B.; Walker, Lisa J.; Halverson, Rich; Jita, Loyiso

    2001-10-01

    This article explores school leadership for elementary school science teaching in an urban setting. We examine how school leaders bring resources together to enhance science instruction when there appear to be relatively few resources available for it. From our study of 13 Chicago elementary (K-8) schools' efforts to lead instructional change in mathematics, language arts, and science education, we show how resources for leading instruction are unequally distributed across subject areas. We also explore how over time leaders in one school successfully identified and activated resources for leading change in science education. The result has been a steady, although not always certain, development of science as an instructional area in the school. We argue that leading change in science education involves the identification and activation of material resources, the development of teachers' and school leaders' human capital, and the development and use of social capital.

  4. Natural resources management activities and biodiversity maintenance. Progress report, July 1, 1994--June 30, 1995

    SciTech Connect

    Caudell, M.B.

    1995-05-01

    This progress report for the Natural Resources Management Activities and Biodiversity Maintenance for the time period July 1, 1994 - June 30, 1995 was submitted to the DOE by the South Carolina Department of Natural Resources. The activities devoted to revitilization of wildlife areas and reintroduction of various animal species to wildlife areas (such as Crackerneck Wildlife Management Area) are described. Other information regarding site characterization, land use and resource management in South Carolina is provided. Also, a description of attendence to various meetings and certification seminars is covered.

  5. Plans and resources required for a computer numerically controlled machine tool tester

    SciTech Connect

    Newton, L.E.; Burleson, R.R.; McCue, H.K.; Pomernacki, C.L.; Mansfield, A.R.; Childs, J.J.

    1982-07-19

    Precision computer numerically controlled (CNC) machine tools present unique and especially difficult problems in the areas of qualification and fault isolation. In this report, we examine and classify these problems, discuss methods to resolve them effectively, and present estimates of the resources needed to design and build a CNC/machine tool tester.

  6. A Second Look at Alternative Projections of Resource Requirements for Teacher Corps Information Sharing and Dissemination.

    ERIC Educational Resources Information Center

    Eckenrod, James S.

    Resources necessary to maintain a valid information dissemination system for the Teacher Corps are identified in this report. Emphasis is placed upon practical cost-effective mechanisms that may be employed in extending educational improvements developed by the Corps. Previous studies have indicated that most Teacher Corps projects will need…

  7. 10 CFR 719.15 - What are the requirements for a staffing and resource plan?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... describing: (1) Major phases likely to be involved in the handling of the matter; (2) Timing and sequence of such phases; (3) Projected cost for each phase of the representation; and (4) Numbers and mix of... staffing and resource plan must include a budget, broken down by phases, including at a minimum: (1)...

  8. 10 CFR 719.15 - What are the requirements for a staffing and resource plan?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... describing: (1) Major phases likely to be involved in the handling of the matter; (2) Timing and sequence of such phases; (3) Projected cost for each phase of the representation; and (4) Numbers and mix of... staffing and resource plan must include a budget, broken down by phases, including at a minimum: (1)...

  9. 10 CFR 719.15 - What are the requirements for a staffing and resource plan?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... describing: (1) Major phases likely to be involved in the handling of the matter; (2) Timing and sequence of such phases; (3) Projected cost for each phase of the representation; and (4) Numbers and mix of... staffing and resource plan must include a budget, broken down by phases, including at a minimum: (1)...

  10. Plant active components - a resource for antiparasitic agents?

    PubMed

    Anthony, Jean-Paul; Fyfe, Lorna; Smith, Huw

    2005-10-01

    Plant essential oils (and/or active components) can be used as alternatives or adjuncts to current antiparasitic therapies. Garlic oil has broad-spectrum activity against Trypanosoma, Plasmodium, Giardia and Leishmania, and Cochlospermum planchonii and Croton cajucara oils specifically inhibit Plasmodium falciparum and Leishmania amazonensis, respectively. Some plant oils have immunomodulatory effects that could modify host-parasite immunobiology, and the lipid solubility of plant oils might offer alternative, transcutaneous delivery routes. The emergence of parasites resistant to current chemotherapies highlights the importance of plant essential oils as novel antiparasitic agents. PMID:16099722

  11. Adult Active Transport in the Netherlands: An Analysis of Its Contribution to Physical Activity Requirements

    PubMed Central

    Fishman, Elliot; Böcker, Lars; Helbich, Marco

    2015-01-01

    Introduction Modern, urban lifestyles have engineered physical activity out of everyday life and this presents a major threat to human health. The Netherlands is a world leader in active travel, particularly cycling, but little research has sought to quantify the cumulative amount of physical activity through everyday walking and cycling. Methods Using data collected as part of the Dutch National Travel Survey (2010 – 2012), this paper determines the degree to which Dutch walking and cycling contributes to meeting minimum level of physical activity of 150 minutes of moderate intensity aerobic activity throughout the week. The sample includes 74,465 individuals who recorded at least some travel on the day surveyed. As physical activity benefits are cumulative, all walking and cycling trips are analysed, including those to and from public transport. These trips are then converted into an established measure of physical activity intensity, known as metabolic equivalents of tasks. Multivariate Tobit regression models were performed on a range of socio-demographic, transport resources, urban form and meteorological characteristics. Results The results reveal that Dutch men and women participate in 24 and 28 minutes of daily physical activity through walking and cycling, which is 41% and 55% more than the minimum recommended level. It should be noted however that some 57% of the entire sample failed to record any walking or cycling, and an investigation of this particular group serves as an important topic of future research. Active transport was positively related with age, income, bicycle ownership, urban density and air temperature. Car ownership had a strong negative relationship with physically active travel. Conclusion The results of this analysis demonstrate the significance of active transport to counter the emerging issue of sedentary lifestyle disease. The Dutch experience provides other countries with a highly relevant case study in the creation of

  12. Consumer Education, 5-8: Activities, Resources and Evaluation.

    ERIC Educational Resources Information Center

    Phillips, Perry D.; Murray, C. Kenneth

    This publication suggests consumer education learning activities for grades five through eight. It is intended as a guideline for developing local curriculum and for designing instructional strategies. Students are taught to learn to manage, to buy wisely, to save and invest, to protect themselves from unscrupulous practice, and to understand the…

  13. Expanding Adolescent Role Expectations. Information, Activities, Resources for Vocational Educators.

    ERIC Educational Resources Information Center

    Cornell Univ., Ithaca, NY. Dept. of Community Service Education.

    Developed for vocational educators as a self-study guide or as a basis for inservice workshops, this source book presents information on sex fair education. Each of the six sections contains fact sheets and references, and some contain checklists, guidelines or rating sheets, and highlighted questions and activities which may be used for…

  14. The Impact of Library Resources and Services on the Scholarly Activity of Medical Faculty and Residents.

    PubMed

    Quesenberry, Alexandria C; Oelschlegel, Sandy; Earl, Martha; Leonard, Kelsey; Vaughn, Cynthia J

    2016-01-01

    Librarians at an academic medical center library gathered data to determine if library services and resources impacted scholarly activity. A survey was developed and sent out to faculty and residents asking how they used the library during scholarly activity. Sixty-five faculty members and residents responded to the survey. The majority of respondents involved with scholarly activity use the library's services and resources. PubMed is the most frequently used database. The positive results show the library impacts the scholarly activity of medical faculty and residents. PMID:27391176

  15. Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity

    PubMed Central

    Pedersen, Nina Marie; Thorvaldsen, Tor Espen; Schultz, Sebastian Wolfgang; Wenzel, Eva Maria; Stenmark, Harald

    2016-01-01

    In canonical Wnt signaling, the protein levels of the key signaling mediator β-catenin are under tight regulation by the multimeric destruction complex that mediates proteasomal degradation of β-catenin. In colorectal cancer, destruction complex activity is often compromised due to mutations in the multifunctional scaffolding protein Adenomatous Polyposis Coli (APC), leading to a stabilization of β-catenin. Recently, tankyrase inhibitors (TNKSi), a novel class of small molecule inhibitors, were shown to re-establish a functional destruction complex in APC-mutant cancer cell lines by stabilizing AXIN1/2, whose protein levels are usually kept low via poly(ADP-ribosyl)ation by the tankyrase enzymes (TNKS1/2). Surprisingly, we found that for the formation of the morphological correlates of destruction complexes, called degradasomes, functional proteasomes are required. In addition we found that AXIN2 is strongly upregulated after 6 h of TNKS inhibition. The proteasome inhibitor MG132 counteracted TNKSi-induced degradasome formation and AXIN2 stabilization, and this was accompanied by reduced transcription of AXIN2. Mechanistically we could implicate the transcription factor FoxM1 in this process, which was recently shown to be a transcriptional activator of AXIN2. We observed a substantial reduction in TNKSi-induced stabilization of AXIN2 after siRNA-mediated depletion of FoxM1 and found that proteasome inhibition reduced the active (phosphorylated) fraction of FoxM1. This can explain the decreased protein levels of AXIN2 after MG132 treatment. Our findings have implications for the design of in vitro studies on the destruction complex and for clinical applications of TNKSi. PMID:27482906

  16. Tim-1-Mediated T Cell Activation Requires Recruitment and Activation of PI 3-Kinase

    PubMed Central

    de Souza, Anjali J.; Oak, Jean S.; Jordanhazy, Ryan; DeKruyff, Rosemarie H.; Fruman, David A.; Kane, Lawrence P.

    2009-01-01

    Ligation of the transmembrane protein Tim-1 can co-stimulate T cell activation. Agonistic antibodies to Tim-1 are also capable of inducing T cell activation without additional stimuli. However, little is known about the biochemical mechanisms underlying T cell stimulation or co-stimulation through Tim-1. We show that a tyrosine in Tim-1 becomes phosphorylated in an lck-dependent manner, whereupon it can directly recruit p85 adaptor subunits of PI 3-kinase. This results in PI3K activation, which is required for Tim-1 function. We also provide genetic evidence that p85 expression is required for optimal Tim-1 function. Thus, we describe a pathway from Tim-1 tyrosine phosphorylation to the PI3K signaling pathway, which appears to be a major effector of Tim-1-mediated T cell activation. PMID:18453570

  17. 48 CFR 1852.204-76 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the IT Security Web site at https://itsecurity.nasa.gov/policies/index.html. (d) The contractor shall... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Security requirements for... CONTRACT CLAUSES Texts of Provisions and Clauses 1852.204-76 Security requirements for...

  18. User requirements and user acceptance of current and next-generation satellite mission and sensor complement, oriented toward the monitoring of water resources

    NASA Technical Reports Server (NTRS)

    Castruccio, P. A.; Loats, H. L., Jr.; Fowler, T. R.; Robinson, P.

    1975-01-01

    Principal water resources users were surveyed to determine the applicability of remotely sensed data to their present and future requirements. Analysis of responses was used to assess the levels of adequacy of LANDSAT 1 and 2 in fulfilling hydrological functions, and to derive systems specifications for future water resources-oriented remote sensing satellite systems. The analysis indicates that water resources applications for all but the very large users require: (1) resolutions on the order of 15 meters, (2) a number of radiometric levels of the same order as currently used in LANDSAT 1 (64), (3) a number of spectral bands not in excess of those used in LANDSAT 1, and (4) a repetition frequency on the order of 2 weeks. The users had little feel for the value of new sensors (thermal IR, passive and active microwaves). What is needed in this area is to achieve specific demonstrations of the utility of these sensors and submit the results to the users to evince their judgement.

  19. Natural products as a resource for biologically active compounds

    SciTech Connect

    Hanke, F.J.

    1986-01-01

    The goal of this study was to investigate various sources of biologically active natural products in an effort to identify the active pesticidal compounds involved. The study is divided into several parts. Chapter 1 contains a discussion of several new compounds from plant and animal sources. Chapter 2 introduces a new NMR technique. In section 2.1 a new technique for better utilizing the lanthanide relaxation agent Gd(fod)/sub 3/ is presented which allows the predictable removal of resonances without line broadening. Section 2.2 discusses a variation of this technique for use in an aqueous solvent by applying this technique towards identifying the binding sites of metals of biological interest. Section 2.3 presents an unambiguous /sup 13/C NMR assignment of melibiose. Chapter 3 deals with work relating to the molting hormone of most arthropods, 20-hydroxyecdysone. Section 3.1 discusses the use of two-dimensional NMR (2D NMR) to assign the /sup 1/H NMR spectrum of this biologically important compound. Section 3.2 presents a new application for Droplet countercurrent chromatography (DCCC). Chapter 4 presents a basic improvement to the commercial DCCC instrument that is currently being applied to future commercial instruments. Chapter 5 discusses a curious observation of the effects that two previously known compounds, nagilactone C and (-)-epicatechin, have on lettuce and rice and suggest a possible new role for the ubiquitous flavanol (-)-epicatechin in plants.

  20. Annual report on the U.S. Department of Energy`s Cultural Resource Activities at Colorado UMTRA Project Sites for October 1993 through September 1994

    SciTech Connect

    Not Available

    1994-11-01

    This report summarizes the results of cultural resource activities conducted by the U.S. Department of Energy (DOE) at Uranium Mill Tailings Remedial Action (UMTRA) Project sites in Colorado for the period of October 1, 1993, through September 30, 1994. The UMTRA Project is a cooperative (state and federal) program mandated by the Uranium Mill Tailings Radiation Control Act, Public Law 95-604 (42 USC {section}7901 et seq.). This law requires the timely cleanup of 24 inactive uranium mill tailings sites throughout the United States. Nine of these inactive uranium mill tailings sites are in Colorado at Durango, Grand Junction, Gunnison, Maybell, Naturita, Rifle, and Slick Rock. On December 6, 1984, the DOE, Advisory Council on Historic Preservation, and Colorado State Historic Preservation Officer (SHPO) entered into a programmatic memorandum of agreement (PMOA) (DOE, 1984). This PMOA specifies requirements for the DOE`s fulfillment of its obligations under various state and federal regulations for the protection and preservation of cultural resources. This report fulfills the requirement for the DOE to provide the state of Colorado with an annual report on the cultural resource activities performed for all of the UMTRA Project sites in Colorado. This report is organized by UMTRA Project site. For each site, the general remedial action activities and cultural resource activities performed during the period of record are summarized. When known, the DOE`s plans for future cultural resource activities at the site are summarized.

  1. Resources for physical activity in cancer centers in the United States.

    PubMed

    Karvinen, Kristina H; Carr, Lucas J; Stevinson, Clare

    2013-12-01

    Physical activity (PA) has many benefits for cancer survivors. However, the available PA resources for survivors at cancer centers throughout the United States are undocumented. The current study surveyed major cancer centers concerning the availability and types (e.g., facilities, programs, counseling, information resources) of PA resources available. Of supportive care services, PA resources were the least commonly reported. Significant correlations were found among availability of PA resources and other supportive care services. Although many cancer centers reported offering PA programming, formal and informal PA guidance and support seem to fall on oncology nurses and other clinicians. Oncology nurses should be reminded that they may be one of the only sources of PA guidance available to survivors at cancer centers. PMID:24305494

  2. Access to environmental resources and physical activity levels of adults in Hawaii

    PubMed Central

    Geller, KS; Nigg, CR; Ollberding, NJ; Motl, RW; Horwath, C; Dishman, RK

    2012-01-01

    Purpose Examine associations between physical activity (PA) and spatial accessibility to environmental PA resources in Hawaii. Methods Metabolic equivalents (METs) of mild, moderate, and strenuous PA were compared for accessibility to environmental PA resources within a population-based sample of Hawaiian adults (n=381). Multiple linear regression estimated differences in PA levels for residing further from a PA resource or residing in an area with a greater number of resources. Results No associations were found in the total sample. Analyses within subsamples stratified by ethnicity revealed that greater spatial accessibility to a PA resource was positively associated with strenuous PA among Caucasians (p=0.04), but negatively associated with moderate PA among Native Hawaiians (p=0.00). Conclusion The lack of association in the total sample may be a consequence of Hawaii’s unique environment. Results of stratified sample analyses are unique, providing groundwork for future examinations within parallel environments and among similar ethnic groups. PMID:22500037

  3. Lipoprotein lipase activity is required for cardiac lipid droplet production.

    PubMed

    Trent, Chad M; Yu, Shuiqing; Hu, Yunying; Skoller, Nathan; Huggins, Lesley A; Homma, Shunichi; Goldberg, Ira J

    2014-04-01

    The rodent heart accumulates TGs and lipid droplets during fasting. The sources of heart lipids could be either FFAs liberated from adipose tissue or FAs from lipoprotein-associated TGs via the action of lipoprotein lipase (LpL). Because circulating levels of FFAs increase during fasting, it has been assumed that albumin transported FFAs are the source of lipids within heart lipid droplets. We studied mice with three genetic mutations: peroxisomal proliferator-activated receptor α deficiency, cluster of differentiation 36 (CD36) deficiency, and heart-specific LpL deletion. All three genetically altered groups of mice had defective accumulation of lipid droplet TGs. Moreover, hearts from mice treated with poloxamer 407, an inhibitor of lipoprotein TG lipolysis, also failed to accumulate TGs, despite increased uptake of FFAs. TG storage did not impair maximal cardiac function as measured by stress echocardiography. Thus, LpL hydrolysis of circulating lipoproteins is required for the accumulation of lipids in the heart of fasting mice. PMID:24493834

  4. EGI-EUDAT integration activity - Pair data and high-throughput computing resources together

    NASA Astrophysics Data System (ADS)

    Scardaci, Diego; Viljoen, Matthew; Vitlacil, Dejan; Fiameni, Giuseppe; Chen, Yin; sipos, Gergely; Ferrari, Tiziana

    2016-04-01

    EGI (www.egi.eu) is a publicly funded e-infrastructure put together to give scientists access to more than 530,000 logical CPUs, 200 PB of disk capacity and 300 PB of tape storage to drive research and innovation in Europe. The infrastructure provides both high throughput computing and cloud compute/storage capabilities. Resources are provided by about 350 resource centres which are distributed across 56 countries in Europe, the Asia-Pacific region, Canada and Latin America. EUDAT (www.eudat.eu) is a collaborative Pan-European infrastructure providing research data services, training and consultancy for researchers, research communities, research infrastructures and data centres. EUDAT's vision is to enable European researchers and practitioners from any research discipline to preserve, find, access, and process data in a trusted environment, as part of a Collaborative Data Infrastructure (CDI) conceived as a network of collaborating, cooperating centres, combining the richness of numerous community-specific data repositories with the permanence and persistence of some of Europe's largest scientific data centres. EGI and EUDAT, in the context of their flagship projects, EGI-Engage and EUDAT2020, started in March 2015 a collaboration to harmonise the two infrastructures, including technical interoperability, authentication, authorisation and identity management, policy and operations. The main objective of this work is to provide end-users with a seamless access to an integrated infrastructure offering both EGI and EUDAT services and, then, pairing data and high-throughput computing resources together. To define the roadmap of this collaboration, EGI and EUDAT selected a set of relevant user communities, already collaborating with both infrastructures, which could bring requirements and help to assign the right priorities to each of them. In this way, from the beginning, this activity has been really driven by the end users. The identified user communities are

  5. Waterworks Book. An Activity Book about Mississippi's Coastal Resources for Primary Grades.

    ERIC Educational Resources Information Center

    Howe, Kevin M.

    Coastal resources are highlighted in this activity book for primary school children. Special focus is given to Mississippi's coastal areas, but applications to other geographic areas can be made. Wetland concepts and conditions are developed through a variety of games, puzzles, matching exercises and pictorial explanations. Activities addressing…

  6. 34 CFR 656.3 - What activities define a comprehensive or undergraduate National Resource Center?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false What activities define a comprehensive or undergraduate....3 What activities define a comprehensive or undergraduate National Resource Center? A comprehensive... science, technology, engineering, and mathematics fields to achieve foreign language...

  7. 34 CFR 656.3 - What activities define a comprehensive or undergraduate National Resource Center?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false What activities define a comprehensive or undergraduate....3 What activities define a comprehensive or undergraduate National Resource Center? A comprehensive... science, technology, engineering, and mathematics fields to achieve foreign language...

  8. Solid Waste Educational Resources and Activities: Let's Reduce, Reuse, and Recycle. [CD-ROM].

    ERIC Educational Resources Information Center

    Environmental Protection Agency, Washington, DC. Solid Waste and Emergency Response.

    This contains games, activities, publications, and resources for students and teachers on how to reduce, reuse, recycle, and properly manage waste. It also contains a screen saver featuring runners-up from the Earth Day 2000 art contest. Activities and games include titles such as "Planet Protectors,""Recycle City,""Trash and Climate Change," and…

  9. Super Saver Investigators: An Elementary, Interdisciplinary, Environmental Studies Activity Guidebook about Solid Waste and Natural Resources.

    ERIC Educational Resources Information Center

    Landis, David; And Others

    This is an elementary, interdisciplinary, environmental studies activity guidebook about solid waste and natural resources. "Super Saver Investigators" what solid waste is, where it is generated, how we manage it and could manage it better, and the consequence of mismanagement. It contains many hands-on, skill enhancing activities for elementary…

  10. Young Children's Exploration of Semiotic Resources during Unofficial Computer Activities in the Classroom

    ERIC Educational Resources Information Center

    Bjorkvall, Anders; Engblom, Charlotte

    2010-01-01

    The article describes and discusses the learning potential of unofficial techno-literacy activities in the classroom with regards to Swedish 7-8-year-olds' exploration of semiotic resources when interacting with computers. In classroom contexts where every child works with his or her own computer, such activities tend to take up a substantial…

  11. Curriculum Resources for Environmental Progress, Vol. 1: Curriculum Outline and Activities Guide.

    ERIC Educational Resources Information Center

    Kalamazoo Nature Center, Inc., MI.

    This publication is the first volume of curriculum resources published by the Kalamazoo Nature Center. It contains directions for using the curriculum activities guide and suggests ways of implementing the activities in the classroom. Also included is an outline of the material that could be covered in an environmental education program, with…

  12. Latino Adolescents' Participation in Extracurricular Activities: How Important Are Family Resources and Cultural Orientation?

    ERIC Educational Resources Information Center

    Simpkins, Sandra D.; O'Donnell, Megan; Delgado, Melissa Y.; Becnel, Jennifer N.

    2011-01-01

    Latino adolescents often are less likely to participate in extracurricular activities compared to youth from other ethnic groups. This descriptive study examined the differences in activity participation by family resources and markers of cultural orientation for the four largest Latino ethnic groups in the U.S. Findings were based on secondary…

  13. Activated Rac1 requires gp130 for Stat3 activation, cell proliferation and migration

    SciTech Connect

    Arulanandam, Rozanne; Geletu, Mulu; Feracci, Helene; Raptis, Leda

    2010-03-10

    Rac1 (Rac) is a member of the Rho family of small GTPases which controls cell migration by regulating the organization of actin filaments. Previous results suggested that mutationally activated forms of the Rho GTPases can activate the Signal Transducer and Activator of Transcription-3 (Stat3), but the exact mechanism is a matter of controversy. We recently demonstrated that Stat3 activity of cultured cells increases dramatically following E-cadherin engagement. To better understand this pathway, we now compared Stat3 activity levels in mouse HC11 cells before and after expression of the mutationally activated Rac1 (Rac{sup V12}), at different cell densities. The results revealed for the first time a dramatic increase in protein levels and activity of both the endogenous Rac and Rac{sup V12} with cell density, which was due to inhibition of proteasomal degradation. In addition, Rac{sup V12}-expressing cells had higher Stat3, tyrosine-705 phosphorylation and activity levels at all densities, indicating that Rac{sup V12} is able to activate Stat3. Further examination of the mechanism of Stat3 activation showed that Rac{sup V12} expression caused a surge in mRNA of Interleukin-6 (IL6) family cytokines, known potent Stat3 activators. Knockdown of gp130, the common subunit of this family reduced Stat3 activity, indicating that these cytokines may be responsible for the Stat3 activation by Rac{sup V12}. The upregulation of IL6 family cytokines was required for cell migration and proliferation induced by Rac{sup V12}, as shown by gp130 knockdown experiments, thus demonstrating that the gp130/Stat3 axis represents an essential effector of activated Rac for the regulation of key cellular functions.

  14. Offshore Resource Assessment and Design Conditions: A Data Requirements and Gaps Analysis for Offshore Renewable Energy Systems

    SciTech Connect

    Elliott, Dennis; Frame, Caitlin; Gill, Carrie; Hanson, Howard; Moriarty, Patrick; Powell, Mark; Shaw, William J.; Wilczak, Jim; Wynne, Jason

    2012-03-01

    The offshore renewable energy industry requires accurate meteorological and oceanographic (“metocean”) data for evaluating the energy potential, economic viability, and engineering requirements of offshore renewable energy projects. It is generally recognized that currently available metocean data, instrumentation, and models are not adequate to meet all of the stakeholder needs on a national scale. Conducting wind and wave resource assessments and establishing load design conditions requires both interagency collaboration as well as valuable input from experts in industry and academia. Under the Department of Energy and Department of Interior Memorandum of Understanding, the Resource Assessment and Design Condition initiative supports collaborative national efforts by adding to core atmospheric and marine science knowledge relevant to offshore energy development. Such efforts include a more thorough understanding and data collection of key metocean phenomena such as wind velocity and shear; low-level jets; ocean, tidal, and current velocities; wave characteristics; geotechnical data relating to surface and subsurface characteristics; seasonal and diurnal variations; and the interaction among these conditions. Figure 1 presents a graphical representation of some metocean phenomena that can impact offshore energy systems. This document outlines the metocean observations currently available; those that are not available; and those that require additional temporal-spatial coverage, resolution, or processing for offshore energy in an effort to gather agreed-upon, needed observations.

  15. 20 CFR 655.1302 - Required pre-filing activity.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... requirements for agricultural clearance orders in 20 CFR part 653 Subpart F and the requirements set forth in § 655.104. (3) The SWA will review the contents of the job order as provided in 20 CFR part 653 Subpart... prior to completion of the housing inspection required by 20 CFR 653.501(d)(6) where necessary to...

  16. 20 CFR 655.1302 - Required pre-filing activity.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... requirements for agricultural clearance orders in 20 CFR part 653 Subpart F and the requirements set forth in § 655.104. (3) The SWA will review the contents of the job order as provided in 20 CFR part 653 Subpart... prior to completion of the housing inspection required by 20 CFR 653.501(d)(6) where necessary to...

  17. Return to Flight: Crew Activities Resource Reel 1 of 2

    NASA Technical Reports Server (NTRS)

    2005-01-01

    The crew of the STS-114 Discovery Mission is seen in various aspects of training for space flight. The crew activities include: 1) STS-114 Return to Flight Crew Photo Session; 2) Tile Repair Training on Precision Air Bearing Floor; 3) SAFER Tile Inspection Training in Virtual Reality Laboratory; 4) Guidance and Navigation Simulator Tile Survey Training; 5) Crew Inspects Orbital Boom and Sensor System (OBSS); 6) Bailout Training-Crew Compartment; 7) Emergency Egress Training-Crew Compartment Trainer (CCT); 8) Water Survival Training-Neutral Buoyancy Lab (NBL); 9) Ascent Training-Shuttle Motion Simulator; 10) External Tank Photo Training-Full Fuselage Trainer; 11) Rendezvous and Docking Training-Shuttle Engineering Simulator (SES) Dome; 12) Shuttle Robot Arm Training-SES Dome; 13) EVA Training Virtual Reality Lab; 14) EVA Training Neutral Buoyancy Lab; 15) EVA-2 Training-NBL; 16) EVA Tool Training-Partial Gravity Simulator; 17) Cure in Place Ablator Applicator (CIPAA) Training Glove Vacuum Chamber; 16) Crew Visit to Merritt Island Launch Area (MILA); 17) Crew Inspection-Space Shuttle Discovery; and 18) Crew Inspection-External Tank and Orbital Boom and Sensor System (OBSS). The crew are then seen answering questions from the media at the Space Shuttle Landing Facility.

  18. Idaho National Laboratory Cultural Resource Management Office FY 2010 Activity Report

    SciTech Connect

    Hollie K. Gilbert; Clayton F. Marler; Christina L. Olson; Brenda R. Pace; Julie Braun Williams

    2011-09-01

    The Idaho National Laboratory (INL) Site is home to vast numbers and a wide variety of important cultural resources representing at least a 13,500 year span of human land use in the region. As a federal agency, the Department of Energy, Idaho Operations Office (DOE-ID) has legal responsibility for the management and protection of the resources and has contracted these responsibilities to Battelle Energy Alliance (BEA). The BEA professional staff is committed to maintaining a cultural resource management program that accepts the challenge of preserving INL cultural resources in a manner reflecting their importance in local, regional, and national history. This report summarizes activities performed by the INL Cultural Resource Management Office (CRMO) staff during fiscal year 2010. This work is diverse, far-reaching and though generally confined to INL cultural resource compliance, also includes a myriad of professional and voluntary community activities. This document is intended to be informative to both internal and external stakeholders and to serve as a planning tool for future INL cultural resource management work.

  19. Brine production strategy modeling for active and integrated management of water resources in CCS

    NASA Astrophysics Data System (ADS)

    Court, B.; Celia, M. A.; Nordbotten, J. M.; Buscheck, T. A.; Elliot, T. J.; Bandilla, K.; Dobossy, M.

    2010-12-01

    Our society is at present highly dependent on coal, which will continue to play a major role in baseload electricity production in the coming decades. Most projected climate change mitigation strategies require CO2 Capture and Sequestration (CCS) as a vital element to stabilize CO2 atmospheric emissions. In these strategies, CCS will have to expand in the next two decades by several orders of magnitude compared to current worldwide implementation. At present the interactions among freshwater extraction, CO2 injection, and brine management are being considered too narrowly across CCS operations, and in the case of freshwater almost completely overlooked. Following the authors’ recently published overview of these challenges, an active and integrated management of water resources throughout CCS operations was proposed to avoid overlooking critical challenges that may become major obstacles to CCS implementation. Water resources management is vital for several reasons including that a coal-fired power plant retrofitted for CCS requires twice as much cooling water as the original plant. However this increased demand may be accommodated by brine extraction and treatment, which would concurrently function as large-scale pressure management and a potential source of freshwater. Synergistic advantages of such proactive integration that were identified led the authors to concluded that: Active management of CCS operations through an integrated approach -including brine production, treatment, use for cooling, and partial reinjection- can address challenges simultaneously with several synergistic advantages; and, that freshwater and brine must be linked to CO2 and pressure as key decision making parameters throughout CCS operations while recognizing scalability and potential pore space competition challenges. This work presents a detailed modeling investigation of a potential integration opportunity resulting from brine production. Technical results will focus solely on the

  20. A National Assessment of the Potential Impacts of Hydraulic Fracturing Activities on Drinking Water Resources

    NASA Astrophysics Data System (ADS)

    Ridley, C.; Burden, S.; Fleming, M. M.; Knightes, C. D.; Koplos, J.; LeDuc, S. D.; Ring, S.; Stanek, J.; Tuccillo, M. E.; Weaver, J.; Frithsen, J.

    2015-12-01

    The U.S. Environmental Protection Agency recently released a draft assessment of the potential impacts of hydraulic fracturing on drinking water resources. As part of the draft assessment, we reviewed, analyzed, and synthesized information from over 950 sources and concluded that there are above and below ground mechanisms by which hydraulic fracturing activities have the potential to impact drinking water resources. These mechanisms include: Water withdrawals in times of, or in areas with, low water availability; Spills of hydraulic fracturing fluids and produced water; Fracturing directly into underground drinking water resources; Below ground migration of liquids and gases; and Inadequate treatment and discharge of wastewater. Of the potential mechanisms identified in this report, we found specific instances where one or more mechanisms led to impacts on drinking water resources, including contamination of drinking water wells. The number of identified cases, however, was small compared to the number of hydraulically fractured wells. This finding could reflect a rarity of effects on drinking water resources, but may also be due to other limiting factors. These factors include: insufficient pre- and post-fracturing data on the quality of drinking water resources; the paucity of long-term systematic studies; the presence of other sources of contamination precluding a definitive link between hydraulic fracturing activities and an impact; and the inaccessibility of some information on hydraulic fracturing activities and potential impacts. Disclaimer: The views expressed are those of the authors and do not necessarily reflect the views or polices of the EPA.

  1. Floral resource limitation severely reduces butterfly survival, condition and flight activity in simplified agricultural landscapes.

    PubMed

    Lebeau, Julie; Wesselingh, Renate A; Van Dyck, Hans

    2016-02-01

    Agricultural intensification has a strong negative impact on farmland biodiversity (including flower-visiting insects), but understanding the mechanisms involved in this requires experimental work. We document the impact of nectar limitation on the performance of a flower-visiting insect, the meadow brown butterfly Maniola jurtina. We conducted two types of experiments: a field experiment in agricultural landscapes with grasslands of different management intensity and an experiment in outdoor flight cages in which the nectar supply was simulated. For the field experiment, we introduced an array of nectar resources in intensively managed, nectar-poor meadows and in extensively managed, flower-rich grasslands and counted flower visitors. Despite higher butterfly abundance in the extensive meadows, our introduced nectar sources were more frequently visited in intensive meadows, indicating the lack of floral resources. The 48-h confinement under nectar-poor conditions in the flight cages had a strong negative effect on body condition, flight activity and lifetime survival compared to butterflies under nectar-rich conditions. Female lifespan was reduced by 22% and male lifespan even by 43%. Agricultural landscapes that provide limited amounts of floral nectar, and no high-quality, preferred nectar sources relative to the needs of the flower-visiting species, may create ecological sinks. Regards an insect's performance, the simple presence of nectar is not necessarily functionally adequate. The effectiveness of agri-environmental schemes for flower-visiting insects (e.g. flower strips) could be improved based on ecological and evolutionary insights on the effects of specific nectar quantities and qualities. PMID:26541442

  2. Requirements assessment and operational demands for a resource mapping rover mission to the lunar polar regions

    SciTech Connect

    KLARER,PAUL R.; BINDER,ALAN B.; LENARD,ROGER X.

    2000-01-26

    A preliminary set of requirements for a robotic rover mission to the lunar polar region are described and assessed. Tasks to be performed by the rover include core drill sample acquisition, mineral and volatile soil content assay, and significant wide area traversals. Assessment of the postulated requirements is performed using first order estimates of energy, power, and communications throughput issues. Two potential rover system configurations are considered, a smaller rover envisioned as part of a group of multiple rovers, and a larger single rover envisioned along more traditional planetary surface rover concept lines.

  3. An analysis of Mars mission activities and the derivation of Extravehicular Activity System design requirements

    NASA Astrophysics Data System (ADS)

    Wells, Peter J.

    1992-07-01

    This paper describes a design process used to develop an extravehicular system suitable for accomplishing a set of specific missions in a Mars environment. The paper first identifies specific candidate geological and operational missions that require direct extravehicular activity action. The tools and procedures necessary to accomplish these missions are identified. The missions are analyzed in order to produce a set of functional and design requirements for the extravehicular system. A preliminary design of an extravehicular system specifically tailored to accomplish the identified missions is presented.

  4. Resource and energy management of synfuels production with hydrogen and oxygen requirements from electrolysis

    NASA Astrophysics Data System (ADS)

    Shannon, R. H.; Richardson, R. D.

    The Resource and Energy Management System (REM), which uses electrolytic H2 and O2 to produce synthetic crude and light oils from heavy hydrocarbons is described. The heavy hydrocarbon feedstocks include heavy oils, tar sand bitumens, heavy residual oils, oil shale kerogens, liquefied coal, and pyrolytically-extracted coal liquids. The system includes mini-upgraders, which can be implemented in modular form, to pump electrolytically-derived H2 into heavy oils to upgrade their energy content. Projected costs for the production of synthetic light oils using U.S. coal reserves with the REM process after liquefaction are $30-35/bbl, with the H2 costs being a controlling factor. The modular systems could be built in a much shorter time frame than much larger projects, and would be instrumental in establishing the electrolytic H2 production infrastructure needed for eventual full conversion to an H2-based economy.

  5. Verifying properties of concepts spontaneously requires sharing resources with same-modality percept.

    PubMed

    Vermeulen, Nicolas; Chang, Betty; Corneille, Olivier; Pleyers, Gordy; Mermillod, Martial

    2013-03-01

    In the present experiments, participants had to verify properties of concepts but, depending on the trial condition, concept-property pairs were presented via headphones or on the screen. The results showed that participants took longer and were less accurate at verifying conceptual properties when the channel used to present the CONCEPT-property pair and the type of property matched in sensory modality (e.g., LEMON-yellow on screen; BLENDER-loud in headphones) compared to when properties and channel did not match (e.g., LEMON-yellow in headphones; BLENDER-loud on screen). Such interference is consistent with theories of embodied cognition holding that knowledge is grounded in modality-specific systems (Barsalou in Behav Brain Sci 22:577-660, 1999). When the resources of one modality are burdened during the task, processing costs are incurred in a conceptual task (Vermeulen et al. in Cognition 109:287-294, 2008). PMID:23413000

  6. 48 CFR 3052.204-70 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Security requirements for... System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY ACQUISITION REGULATION (HSAR) CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 3052.204-70 Security...

  7. 14 CFR 1274.937 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Computer Security Act of 1987 (40 U.S.C. 1441 et seq.) and the Government Information Security Reform Act... cooperative agreement, receive annual IT security training in NASA IT Security policies, procedures, computer... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Security requirements for...

  8. 14 CFR 1274.937 - Security requirements for unclassified information technology resources.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Computer Security Act of 1987 (40 U.S.C. 1441 et seq.) and the Government Information Security Reform Act... cooperative agreement, receive annual IT security training in NASA IT Security policies, procedures, computer... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Security requirements for...

  9. Learning Activities and Resource Units: Intermediate 4-8. [Arizona] Migrant Child Institute.

    ERIC Educational Resources Information Center

    Wheelock, Warren H., Ed.

    A requirement of Arizona's Migrant Teacher Institutes was the preparation of instructional resource units. Development of these units was a key element in the three-stage recommendations related to individualizing instruction in both reading and oral language. The three stages were: Room Organization--Realistic Learning Centers, Unit Themes and…

  10. Board on Earth Sciences and Resources and Its Activities -- Final Technical Report

    SciTech Connect

    Anthony R. de Souza, Ph.D. Director, Board on Earth Sciences and Resources

    2003-09-26

    The Board on Earth Sciences and Resources (BESR) provided oversight of the earth sciences and resources activities with the National Research Council (NRC). The Board reviewed research and public activities in the earth sciences; undertook analyses relevant to the discovery, supply, delivery, waste disposal and associated impacts and issues related to hydrocarbon, metallic, and nonmetallic mineral resources; and monitored the status of the earth sciences, assessed the health of the disciplines, identified research opportunities, and responded to specific agency requests for advice. These tasks were conducted by distinguished volunteers and NRC staff members that are representative of the breadth and depth of the earth sciences and resources disciplines (e.g., ecology, geophysics, geochemistry, geobiology, hydrology, geography, geographic information science, materials science, mineral resources and mining, energy resources, paleontology, visualization, remote sensing, geophysical data and information). Each year the Board held two meetings. Most recently at the May 2003 Board meeting, the main topic of discussion was Coordination of Geospatial Data in the Era of the Department of Homeland Security. Speakers were Steven Cooper, DHS; Barry Napier, FEMA; Bill Shinar, VGIN; Barbara Ryan, USGS; and Hank Garie, DOI. Other topics were Circum-Pacific Council for Energy and Mineral Resources and New Opportunities in the Geology Discipline (Pat Leahy, USGS); Challenges to Understanding Biological Change in a Fluid Landscape (Sue Haseltine, USGS); and GIS and Remote Sensing at the USDA (Rodney Brown, USDA). The Board and the AGI also held a Leadership Forum. At the October 2003 Board meeting in Irvine, California, the Board plans to discuss earth resource issues, develop a white paper on the future directions of the Board, and review two of its standing committees--Committee on Seismology and Geodynamics, and the Committee on Geological and Geotechnical Engineering. The Board

  11. Advanced Extra-Vehicular Activity Pressure Garment Requirements Development

    NASA Technical Reports Server (NTRS)

    Ross, Amy; Aitchison, Lindsay; Rhodes, Richard

    2015-01-01

    The NASA Johnson Space Center advanced pressure garment technology development team is addressing requirements development for exploration missions. Lessons learned from the Z-2 high fidelity prototype development have reiterated that clear low-level requirements and verification methods reduce risk to the government, improve efficiency in pressure garment design efforts, and enable the government to be a smart buyer. The expectation is to provide requirements at the specification level that are validated so that their impact on pressure garment design is understood. Additionally, the team will provide defined verification protocols for the requirements. However, in reviewing exploration space suit high level requirements there are several gaps in the team's ability to define and verify related lower level requirements. This paper addresses the efforts in requirement areas such as mobility/fit/comfort and environmental protection (dust, radiation, plasma, secondary impacts) to determine the method by which the requirements can be defined and use of those methods for verification. Gaps exist at various stages. In some cases component level work is underway, but no system level effort has begun; in other cases no effort has been initiated to close the gap. Status of on-going efforts and potential approaches to open gaps are discussed.

  12. 20 CFR 655.1302 - Required pre-filing activity.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., maintain dated logs demonstrating that each worker was contacted, including the phone number, e-mail... applicant is satisfied by maintaining proof of posting from the SWA identifying the job order number(s) with... requirements for agricultural clearance orders in 20 CFR part 653 Subpart F and the requirements set forth...

  13. 20 CFR 665.330 - Are the NAFTA-TAA program requirements for rapid response also required activities?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Are the NAFTA-TAA program requirements for... WORKFORCE INVESTMENT ACT Rapid Response Activities § 665.330 Are the NAFTA-TAA program requirements for... WIA are made available to workers who, under the NAFTA Implementation Act (Public Law 103-182),...

  14. Activities of the Water Resources Division in Arizona, 1986-91

    USGS Publications Warehouse

    Spicer, L. M., (compiler); van de Vanter, E.K.

    1993-01-01

    Water-resources activities of the U.S. Geological Survey in Arizona consist of collecting water- resources data and conducting interpretive hydrologic investigations and research. The water- resources data and the results of the interpretive investigations and research are published or released by the U.S. Geological Survey or by cooperating agencies. The report describes the data-collection activities and water-resources investigations in Arizona for fiscal years 1986-91 (October 1, 1985, to September 30, 1991). The report includes a brief description of the origin of the U.S. Geological Survey, the basic mission of the Water Resources Division, organization of the Arizona District, sources of funding, and a summary of water conditions in Arizona. Information is given for each project and includes the objective, approach, progress and results, and plans for the following year. The report also includes a list of publications prepared by the Arizona District, Water Resources Division, U.S. Geological Survey, that were published from 1984 to 1991.

  15. 43 CFR 5.4 - When is a permit required for news-gathering activities?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false When is a permit required for news... Wildlife Service § 5.4 When is a permit required for news-gathering activities? (a) Permit requirements. News-gathering activities involving filming, videography, or still photography do not require a...

  16. 43 CFR 5.4 - When is a permit required for news-gathering activities?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false When is a permit required for news... Wildlife Service § 5.4 When is a permit required for news-gathering activities? (a) Permit requirements. News-gathering activities involving filming, videography, or still photography do not require a...

  17. NASA's SMD Cross-Forum Resources for Supporting Scientist Engagement in Education and Public Outreach Activities

    NASA Astrophysics Data System (ADS)

    Buxner, S.; Cobabe-Ammann, E. A.; Hsu, B. C.; Sharma, M.; Peticolas, L. M.; Schwerin, T. G.; Shipp, S. S.; Smith, D.

    2012-12-01

    Sharing the excitement of ongoing scientific discoveries is an important aspect of scientific activity for researchers. Directly engaging scientists in education and public outreach (E/PO) activities has the benefit of directly connecting the public to those who engage in scientific activities. A shortage of training in education methods, public speaking, and working with various public audiences increases barriers to engaging scientists in these types in E/PO activities. NASA's Science Mission Directorate (SMD) Education and Public forums (astrophysics, earth science, heliophysics, and planetary science) support scientists currently involved in E/PO and who are interested in becoming involved in E/PO through a variety of avenues. Over the past three years, the forums have developed a variety of resources to help engage scientists in education and public outreach. We will showcase the following resources developed through the SMD E/PO cross-forum efforts: Professional development resources for writing NASA SMD E/PO proposals (webinars and other online tools), ongoing professional development at scientific conferences to increase scientist engagement in E/PO activities, toolkits for scientists interested in best practices in E/PO (online guides for K-12 education and public outreach), toolkits to inform scientists of science education resources developed within each scientific thematic community, EarthSpace (a community web space where instructors can find and share about teaching space and earth sciences in the undergraduate classroom, including class materials news and funding opportunities, and the latest education research, http://www.lpi.usra.edu/earthspace/), thematic resources for teaching about SMD science topics, and an online database of scientists interested in connecting with education programs. Learn more about the Forum and find resources at http://smdepo.org/.

  18. Requirements, Resource Planning and Management for Decrewing/Recrewing Scenarios of the International Space Station

    NASA Technical Reports Server (NTRS)

    Bach, David A.; Hasbrook, Peter V.; BBrand, Susan N.

    2012-01-01

    Following the failure of 44P on launch in August 2011, and the subsequent grounding of all Russian Soyuz rocket based launches, the ISS ground teams engaged in an effort to determine how long the ISS could remain crewed, what would be required to safely configure the ISS for decrewing, and what would be required to recrew the ISS upon resumption of Soyuz rocket launches if decrewing became necessary. This White Paper was written to capture the processes and lessons learned from real-time time events and to provide a reference and training document for ISS Program teams in the event decrewing of the ISS is needed. Through coordination meetings and assessments, teams identified six decrewing priorities for ground and crew operations. These priorities were integrated along with preflight priorities through the Increment replanning process. Additionally, the teams reviewed, updated, and implemented changes to the governing documentation for the configuration of the ISS for a contingency decrewing event. Steps were taken to identify critical items for disposal prior to decrewing, as well as identifying the required items to be strategically staged or flown with the astronauts and cosmonauts who would eventually recrew the ISS. After the successful launches and dockings of both 45P and 28S, the decrewing team transitioned to finalizing and publishing the documentation for standardizing the decrewing flight rules. With the continued launching of crews and cargo to the ISS, utilization and science is again a high priority, with the Increment pairs 29 and 30, and 31 and 32 reaching the milestone of at least 35 hours per week average utilization.

  19. Requirements, Resource Planning, and Management for Decrewing/Recrewing Scenarios of the International Space Station

    NASA Technical Reports Server (NTRS)

    Bach, David A.; Brand, Susan N.; Hasbrook, Peter V.

    2013-01-01

    Following the failure of 44 Progress (44P) on launch in August 2011, and the subsequent grounding of all Russian Soyuz rocket based launches, the International Space Station (ISS) ground teams engaged in an effort to determine how long the ISS could remain crewed, what would be required to safely configure the ISS for decrewing, and what would be required to recrew the ISS upon resumption of Soyuz rocket launches if decrewing became necessary. This White Paper was written to capture the processes and lessons learned from real-time time events and to provide a reference and training document for ISS Program teams in the event decrewing of the ISS is needed. Through coordination meetings and assessments, teams identified six decrewing priorities for ground and crew operations. These priorities were integrated along with preflight priorities through the Increment re-planning process. Additionally, the teams reviewed, updated, and implemented changes to the governing documentation for the configuration of the ISS for a contingency decrewing event. Steps were taken to identify critical items for disposal prior to decrewing, as well as identifying the required items to be strategically staged or flown with the astronauts and cosmonauts who would eventually recrew the ISS. After the successful launches and dockings of both 45P and 28 Soyuz (28S), the decrewing team transitioned to finalizing and publishing the documentation for standardizing the decrewing flight rules. With the continued launching of crews and cargo to the ISS, utilization and science is again a high priority; both Increment pairs 29 and 30, and Increment 31 and 32 reaching the milestone of at least 35 hours per week average utilization.

  20. Activities of the U.S. Geological Survey Water-Resources Division in North Carolina, 1986

    USGS Publications Warehouse

    Turner, J. F., (compiler); Deckard, R.J.

    1986-01-01

    Water resources programs conducted by the U.S. Geological Survey in the state of North Carolina during 1985 and proposed programs for 1986 are described. This is the first in a series of biennial progress reports on Survey activities in the state. Activities such as gathering, interpreting and publishing hydrologic data and scientific information in support of state and local water resources planning, management, and regulatory programs are presented. The water resources programs described are funded through cooperative agreements with state and local agencies and through special agreements with other federal agencies. Cooperative programs are reviewed annually to insure that state, local and national priorities are being met. Groundwater withdrawals are estimated to have produced water level declines of 150 ft and more for large areas of the northeast and central Coastal Plain. Future demands for water quality and quantity are discussed.

  1. Somali Perspectives on Physical Activity: Photovoice to Address Barriers and Resources in San Diego

    PubMed Central

    Murray, Kate; Mohamed, Amina Sheik; Dawson, Darius B.; Syme, Maggie; Abdi, Sahra; Barnack-Tavlaris, Jessica

    2015-01-01

    Background Though many immigrants enter the U.S. with a healthy body weight, this health advantage disappears the longer they reside in the U.S. To better understand the complexities of obesity change within a cultural framework, a community-based participatory research (CBPR) approach, Photovoice, was utilized focusing on physical activity among Muslim Somali women. Objectives The CBPR partnership was formed to identify barriers and resources to engaging in physical activity with goals of advocacy and program development. Methods Muslim Somali women (n = 8) were recruited to participate, trained and provided cameras, and engaged in group discussions about the scenes they photographed. Results Participants identified several barriers, including safety concerns, minimal culturally appropriate resources, and financial constraints. Strengths included public resources and a community support system. The CBPR process identified opportunities and challenges to collaboration and dissemination processes. Conclusions The findings laid the framework for subsequent program development and community engagement. PMID:25981428

  2. Effects of solar activity in the Portuguese water resources SOLSPA 2001

    NASA Astrophysics Data System (ADS)

    Cunha, Rita

    2002-03-01

    The hydrological time series can be used as guides of tendency and cyclic variation of climate. Although the climatic variability mechanisms are not totally understood, the solar activity variations can be associated with regional hydrometeorological variables. The water resources availability is becoming an urgent problem as the human pressure rises in water demand. The knowledge of hydroclimatic variables tendencies as the relationship between our activities and the quantity and quality of ground and surface resources, is an essential step in the formulation of a sustainable water resources management plane. The major purpose of this study is to use it as a starting point to assess and predict soil water availability and understand its connections with the solar variability.

  3. 33 CFR 322.3 - Activities requiring permits.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... § 322.4 below. Certain activities specified in 33 CFR part 330 are permitted by that regulation... in 33 CFR part 329. Structures or work outside these limits are subject to the provisions of law... the Outer Continental Shelf Lands Act as amended. (See 33 CFR 320.2(b).) (c) Activities of...

  4. 33 CFR 322.3 - Activities requiring permits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... § 322.4 below. Certain activities specified in 33 CFR part 330 are permitted by that regulation... in 33 CFR part 329. Structures or work outside these limits are subject to the provisions of law... the Outer Continental Shelf Lands Act as amended. (See 33 CFR 320.2(b).) (c) Activities of...

  5. 33 CFR 322.3 - Activities requiring permits.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... § 322.4 below. Certain activities specified in 33 CFR part 330 are permitted by that regulation... in 33 CFR part 329. Structures or work outside these limits are subject to the provisions of law... the Outer Continental Shelf Lands Act as amended. (See 33 CFR 320.2(b).) (c) Activities of...

  6. 33 CFR 322.3 - Activities requiring permits.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... § 322.4 below. Certain activities specified in 33 CFR part 330 are permitted by that regulation... in 33 CFR part 329. Structures or work outside these limits are subject to the provisions of law... the Outer Continental Shelf Lands Act as amended. (See 33 CFR 320.2(b).) (c) Activities of...

  7. 33 CFR 322.3 - Activities requiring permits.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... § 322.4 below. Certain activities specified in 33 CFR part 330 are permitted by that regulation... in 33 CFR part 329. Structures or work outside these limits are subject to the provisions of law... the Outer Continental Shelf Lands Act as amended. (See 33 CFR 320.2(b).) (c) Activities of...

  8. Estimating Resource Requirements to Staff a Response to a Medium to Large Outbreak of Foot and Mouth Disease in Australia.

    PubMed

    Garner, M G; Bombarderi, N; Cozens, M; Conway, M L; Wright, T; Paskin, R; East, I J

    2016-02-01

    A recent report to the Australian Government identified concerns relating to Australia's capacity to respond to a medium to large outbreak of FMD. To assess the resources required, the AusSpread disease simulation model was used to develop a plausible outbreak scenario that included 62 infected premises in five different states at the time of detection, 28 days after the disease entered the first property in Victoria. Movements of infected animals and/or contaminated product/equipment led to smaller outbreaks in NSW, Queensland, South Australia and Tasmania. With unlimited staff resources, the outbreak was eradicated in 63 days with 54 infected premises and a 98% chance of eradication within 3 months. This unconstrained response was estimated to involve 2724 personnel. Unlimited personnel was considered unrealistic, and therefore, the course of the outbreak was modelled using three levels of staffing and the probability of achieving eradication within 3 or 6 months of introduction determined. Under the baseline staffing level, there was only a 16% probability that the outbreak would be eradicated within 3 months, and a 60% probability of eradication in 6 months. Deployment of an additional 60 personnel in the first 3 weeks of the response increased the likelihood of eradication in 3 months to 68%, and 100% in 6 months. Deployment of further personnel incrementally increased the likelihood of timely eradication and decreased the duration and size of the outbreak. Targeted use of vaccination in high-risk areas coupled with the baseline personnel resources increased the probability of eradication in 3 months to 74% and to 100% in 6 months. This required 25 vaccination teams commencing 12 days into the control program increasing to 50 vaccination teams 3 weeks later. Deploying an equal number of additional personnel to surveillance and infected premises operations was equally effective in reducing the outbreak size and duration. PMID:24894407

  9. Activities of the Alaska District, Water Resources Division, U.S. Geological Survey, 1990

    USGS Publications Warehouse

    Snyder, Elisabeth F.

    1990-01-01

    Thirteen projects of the U.S. Geological Survey, Water Resource Division active in Alaska in 1990 are described. Each description includes information on period of project, chief, funding sources, location, purpose, current status, and published or planned reports. The compilation also contains a bibliography of reports published by the Alaska District from 1987 through January 1990. (USGS)

  10. Active Remote Sensing of Natural Resources: Course Notes. Science Series No. 5. Final Technical Report.

    ERIC Educational Resources Information Center

    Maxwell, Eugene L.

    Presented is a portion of a research project which developed materials for teaching remote sensing of natural resources on an interdisciplinary basis at the graduate level. This volume contains notes developed for a course in active remote sensing. It is concerned with those methods or systems which generate the electromagnetic energy…

  11. Astronomical! 44 Activities, Experiments, and Projects. Classroom Resource 0-27440.

    ERIC Educational Resources Information Center

    Walker, Ormiston H.

    This is a resource book for four major areas of study: basic astronomy, a star's life, the planets, and the atmosphere. The activities and demonstrations included can be done in a classroom setting during the day by using readily available materials. Topics covered include: refracting and reflecting telescopes, star finder, circumpolar…

  12. Stream mesocosm response sensitivities to simulated ion stress in produced waters from resource extraction activities

    EPA Science Inventory

    To increase the ecological relevance of laboratory exposures intent on determining species sensitivity to ion stress from resource extraction activities we have conducted several stream mesocosm dosing studies that pair single-species and community-level responses in-situ and all...

  13. Technology in College Unions and Student Activities: A Collection of Technology Resources from the ACUI Community

    ERIC Educational Resources Information Center

    Association of College Unions International (NJ1), 2012

    2012-01-01

    This publication presents a collection of technology resources from the Association of College Unions International (ACUI) community. Contents include: (1) Podcasting (Jeff Lail); (2) Video Podcasting (Ed Cabellon); (3) Building a Multimedia Production Center (Nathan Byrer); (4) Cloud Computing in the Student Union and Student Activities (TJ…

  14. Thematic Resources and Activities for Career Education: CEI Final Report: Vol. III.

    ERIC Educational Resources Information Center

    Central Susquehanna Intermediate Unit 16, Lewisburg, PA.

    The book, Volume Three of a final report, is a collection of teachers' guides to units in career education, written by Pennsylvania teachers during a regional inservice institute in career education. The format used, Thematic Resources and Activities for Career Education (TRACE), incorporates the concerns of the Pennsylvania Career Development…

  15. Activities for Learning about Conservation of Forest Resources: A Guide for Leaders of Youth Groups.

    ERIC Educational Resources Information Center

    Forest Service (USDA), Washington, DC.

    This guide is intended to support the leader of a youth group in increasing the awareness of members of the need for good forest conservation practices. Sections include: (1) science fundamentals; (2) making informative exhibits; (3) gaining community involvement; (4) Christmas activities; (5) games and crafts; and (6) a list of resources and…

  16. Global Issues: Activities and Resources for the High School Teacher. Second Edition.

    ERIC Educational Resources Information Center

    Switzer, Kenneth A.; And Others

    Increasing student knowledge about other nations and interrelationships with them is the primary goal of this teaching guide. The activities and resources focus on six topics of continuing global importance: (1) trade and economic issues, (2) conflict and armaments, (3) modernization and development, (4) technology and the environment, (5) energy,…

  17. Readings and Activities for Character Education: A Resource Guide for Teachers and Students.

    ERIC Educational Resources Information Center

    Brooks, Diane L.

    This resource guide, for teachers and students in the upper elementary and middle school grades, has been developed in response to the nationwide interest in asking schools to play an active role in preparing students to become informed and responsible citizens. The guide is divided into seven sections, one for each character trait: Caring, Civic…

  18. Small Schools Mathematics Curriculum, 9-12: Scope Objectives, Activities, Resources, Monitoring Procedures.

    ERIC Educational Resources Information Center

    Nelson, JoAnne, Ed.; And Others

    The grade 9-12 mathematics curriculum learning objectives, activities, monitoring procedures and resources for small schools were developed during 1978-79 through the cooperative efforts of 10 Snohomish and Island County school districts, Educational Service District 189 and the Washington State Office of Public Instruction. The objectives were…

  19. 78 FR 8192 - Agency Information Collection Activities: Comment Request; Education and Human Resources Project...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-05

    ... second notice for public comment; the first was published in the Federal Register at 77 FR 56234 and no... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION Agency Information Collection Activities: Comment Request; Education and Human Resources...

  20. Making a Difference. A Resource Pack for People Who Want To Become More Active Citizens.

    ERIC Educational Resources Information Center

    Dadzie, Stella, Comp.; Turner, Cheryl, Ed.

    This document, which is a resource pack for individuals in the United Kingdom who want to become more active citizens, consists of information for group leaders and five learning modules. The section for group leaders contains the following: basic tips on leading a group; strategies for overcoming barriers to learning; glossary; and overview of…

  1. Small Schools Health Curriculum, K-3: Scope, Objectives, Activities, Resources, Monitoring Procedures.

    ERIC Educational Resources Information Center

    McInerney, Mike, Ed.; Destito, Therese, Ed.

    The K-3 health curriculum developed during 1975-77 by teachers in small school districts working with district and state health education specialists presents student learning objectives and suggested activities, monitoring procedures and resources which are correlated to the 10 Goals for Washington Common Schools and the nine Small Schools Health…

  2. New State Forest Practice Laws. A review of state laws and their natural resource data requirements

    NASA Technical Reports Server (NTRS)

    Klein, S. B.

    1980-01-01

    Forest practice regulations can be established by being specified in state law or by being promulgated by some other official body delegated the authority to do so. At the state level, public regulation of private forest practices resulted in many cases, in the enactment of state forest practice laws regulating both private, and in some cases, public landowner activities. These laws aim not only to protect natural environments, but also to encourage continuous productivity of forest lands, to maintain or enhance aesthetic values, and to serve as an implementing mechanism to control water pollution. Profiles of regulations in California, Idaho, Maine, Nevada, New Hampshire, Oregon, and Washington are examined and assessed. Voluntary guidelines in use in 18 states are summarized.

  3. 10 CFR 810.8 - Activities requiring specific authorization.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... technology for an activity in any foreign country. (c) Engaging in or providing assistance or training in any... plutonium, or the production of heavy water; (2) Constructing, fabricating, operating, or maintaining...

  4. 10 CFR 810.8 - Activities requiring specific authorization.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... technology for an activity in any foreign country. (c) Engaging in or providing assistance or training in any... plutonium, or the production of heavy water; (2) Constructing, fabricating, operating, or maintaining...

  5. Polarity establishment requires localized activation of Cdc42

    PubMed Central

    Woods, Benjamin; Kuo, Chun-Chen; Wu, Chi-Fang; Zyla, Trevin R.

    2015-01-01

    Establishment of cell polarity in animal and fungal cells involves localization of the conserved Rho-family guanosine triphosphatase, Cdc42, to the cortical region destined to become the “front” of the cell. The high local concentration of active Cdc42 promotes cytoskeletal polarization through various effectors. Cdc42 accumulation at the front is thought to involve positive feedback, and studies in the budding yeast Saccharomyces cerevisiae have suggested distinct positive feedback mechanisms. One class of mechanisms involves localized activation of Cdc42 at the front, whereas another class involves localized delivery of Cdc42 to the front. Here we show that Cdc42 activation must be localized for successful polarity establishment, supporting local activation rather than local delivery as the dominant mechanism in this system. PMID:26459595

  6. Available processing resources influence encoding-related brain activity before an event.

    PubMed

    Galli, Giulia; Gebert, A Dorothea; Otten, Leun J

    2013-09-01

    Effective cognitive functioning not only relies on brain activity elicited by an event, but also on activity that precedes it. This has been demonstrated in a number of cognitive domains, including memory. Here, we show that brain activity that precedes the effective encoding of a word into long-term memory depends on the availability of sufficient processing resources. We recorded electrical brain activity from the scalps of healthy adult men and women while they memorized intermixed visual and auditory words for later recall. Each word was preceded by a cue that indicated the modality of the upcoming word. The degree to which processing resources were available before word onset was manipulated by asking participants to make an easy or difficult perceptual discrimination on the cue. Brain activity before word onset predicted later recall of the word, but only in the easy discrimination condition. These findings indicate that anticipatory influences on long-term memory are limited in capacity and sensitive to the degree to which attention is divided between tasks. Prestimulus activity that affects later encoding can only be engaged when the necessary cognitive resources can be allocated to the encoding process. PMID:23219383

  7. 12 CFR 1272.3 - New business activity notice requirement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... written notice containing the following information: (a) General requirements. Except as provided in... procedures for determining the value of the collateral in question, established pursuant to § 1266.10 of this chapter; and (4) A demonstration of the Bank's capacity, personnel, technology, experience and...

  8. 12 CFR 1272.3 - New business activity notice requirement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... written notice containing the following information: (a) General requirements. Except as provided in... procedures for determining the value of the collateral in question, established pursuant to § 1266.10 of this chapter; and (4) A demonstration of the Bank's capacity, personnel, technology, experience and...

  9. 12 CFR 980.3 - New business activity notice requirement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Board a written notice containing the following information: (a) General requirements. Except as... procedures for determining the value of the collateral in question, established pursuant to § 950.10 of this chapter; and (4) A demonstration of the Bank's capacity, personnel, technology, experience and...

  10. 12 CFR 980.3 - New business activity notice requirement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Board a written notice containing the following information: (a) General requirements. Except as... procedures for determining the value of the collateral in question, established pursuant to § 950.10 of this chapter; and (4) A demonstration of the Bank's capacity, personnel, technology, experience and...

  11. 12 CFR 1272.3 - New business activity notice requirement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... written notice containing the following information: (a) General requirements. Except as provided in... procedures for determining the value of the collateral in question, established pursuant to § 1266.10 of this chapter; and (4) A demonstration of the Bank's capacity, personnel, technology, experience and...

  12. Multidisciplinary and Active/Collaborative Approaches in Teaching Requirements Engineering

    ERIC Educational Resources Information Center

    Rosca, Daniela

    2005-01-01

    The requirements engineering course is a core component of the curriculum for the Master's in Software Engineering programme, at Monmouth University (MU). It covers the process, methods and tools specific to this area, together with the corresponding software quality issues. The need to produce software engineers with strong teamwork and…

  13. Requirement for Drosophila SNMP1 for Rapid Activation and Termination of Pheromone-Induced Activity

    PubMed Central

    Li, Zhengzheng; Ni, Jinfei D.; Huang, Jia; Montell, Craig

    2014-01-01

    Pheromones are used for conspecific communication by many animals. In Drosophila, the volatile male-specific pheromone 11-cis vaccenyl acetate (cVA) supplies an important signal for gender recognition. Sensing of cVA by the olfactory system depends on multiple components, including an olfactory receptor (OR67d), the co-receptor ORCO, and an odorant binding protein (LUSH). In addition, a CD36 related protein, sensory neuron membrane protein 1 (SNMP1) is also involved in cVA detection. Loss of SNMP1 has been reported to eliminate cVA responsiveness, and to greatly increase spontaneous activity of OR67d-expressing olfactory receptor neurons (ORNs). Here, we found the snmp11 mutation did not abolish cVA responsiveness or cause high spontaneous activity. The cVA responses in snmp1 mutants displayed a delayed onset, and took longer to reach peak activity than wild-type. Most strikingly, loss of SNMP1 caused a dramatic delay in signal termination. The profound impairment in signal inactivation accounted for the previously reported “spontaneous activity,” which represented continuous activation following transient exposure to environmental cVA. We introduced the silk moth receptor (BmOR1) in OR67d ORNs of snmp11 flies and found that the ORNs showed slow activation and deactivation kinetics in response to the BmOR1 ligand (bombykol). We expressed the bombykol receptor complex in Xenopus oocytes in the presence or absence of the silk moth SNMP1 (BmSNMP) and found that addition of BmSNMP accelerated receptor activation and deactivation. Our results thus clarify SNMP1 as an important player required for the rapid kinetics of the pheromone response in insects. PMID:25255106

  14. 32 CFR Enclosure 2 to Part 187 - Requirements for Environmental Considerations-Foreign Nations and Protected Global Resources

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... procedures (32 CFR 159) established for such information under Executive Order 12065. The requirements of... safeguarded from disclosure in accordance with the DoD procedures (32 CFR 159) established for such... activities of the intelligence components utilized by the Secretary of Defense under Executive Order...

  15. Classical-quantum arbitrarily varying wiretap channel: Ahlswede dichotomy, positivity, resources, super-activation

    NASA Astrophysics Data System (ADS)

    Boche, Holger; Cai, Minglai; Deppe, Christian; Nötzel, Janis

    2016-08-01

    We establish the Ahlswede dichotomy for arbitrarily varying classical-quantum wiretap channels, i.e., either the deterministic secrecy capacity of the channel is zero, or it equals its randomness-assisted secrecy capacity. We analyze the secrecy capacity of these channels when the sender and the receiver use various resources. It turns out that randomness, common randomness, and correlation as resources are very helpful for achieving a positive secrecy capacity. We prove the phenomenon "super-activation" for arbitrarily varying classical-quantum wiretap channels, i.e., two channels, both with zero deterministic secrecy capacity, if used together allow perfect secure transmission.

  16. Water-resources activities of the U.S. Geological Survey in Missouri, fiscal year 1985

    USGS Publications Warehouse

    Kratzer, W.M.; Jenkins, K.L.

    1985-01-01

    Water-resource activities of the U.S. Geological Survey in Missouri consist of collecting hydrologic data and making interpretive studies. These projects are funded through joint-funding agreements with State and local agencies, transfer of funds from other Federal agencies, and direct Federal funds. These data and the results of the investigations are published or released by either the U.S. Geological Survey or by cooperating agencies. This report describes the hydrologic data-collection program and local or areal investigations in Missouri for fiscal year 1985 and provides a list of selected water-resources references for Missouri. (USGS)

  17. Brain feminization requires active repression of masculinization via DNA methylation

    PubMed Central

    Nugent, Bridget M.; Wright, Christopher L.; Shetty, Amol C.; Hodes, Georgia E.; Lenz, Kathryn M.; Mahurkar, Anup; Russo, Scott J.; Devine, Scott E.; McCarthy, Margaret M.

    2015-01-01

    The developing mammalian brain is destined for a female phenotype unless exposed to gonadal hormones during a perinatal sensitive period. It has been assumed that the undifferentiated brain is masculinized by direct induction of transcription by ligand-activated nuclear steroid receptors. We found that a primary effect of gonadal steroids in the highly sexually-dimorphic preoptic area (POA) is to reduce activity of DNA methyltransferase (Dnmt) enzymes, thereby decreasing DNA methylation and releasing masculinizing genes from epigenetic repression. Pharmacological inhibition of Dnmts mimicked gonadal steroids, resulting in masculinized neuronal markers and male sexual behavior in females. Conditional knockout of the de novo Dnmt isoform, Dnmt3a, also masculinized sexual behavior in female mice. RNA sequencing revealed gene and isoform variants modulated by methylation that may underlie the divergent reproductive behaviors of males versus females. Our data show that brain feminization is maintained by the active suppression of masculinization via DNA methylation. PMID:25821913

  18. ACTIVATED SLUDGE CLARIFIERS: DESIGN REQUIREMENTS AND RESEARCH PRIORITIES

    EPA Science Inventory

    The literature review of 320 references was conducted in an EPA-funded project to identify the needs for further research on activated sludge clarifier design and performance. The findings were summarized in a report and used as a basis of a 3-day research needs symposium. The pr...

  19. Giving and taking: Representational building blocks of active resource-transfer events in human infants

    PubMed Central

    Tatone, Denis; Geraci, Alessandra; Csibra, Gergely

    2015-01-01

    Active resource transfer is a pervasive and distinctive feature of human sociality. We hypothesized that humans possess an action schema of giving specific for representing social interactions based on material exchange, and specified the set of necessary assumptions about giving events that this action schema should be equipped with. We tested this proposal by investigating how 12-month-old infants interpret abstract resource-transfer events. Across eight looking-time studies using a violation-of-expectation paradigm we found that infants were able to distinguish between kinematically identical giving and taking actions. Despite the surface similarity between these two actions, only giving was represented as an object-mediated social interaction. While we found no evidence that infants expected the target of a giving or taking action to reciprocate, the present results suggest that infants interpret giving as an inherently social action, which they can possibly use to map social relations via observing resource-transfer episodes. PMID:25614012

  20. Charge Requirements of Lipid II Flippase Activity in Escherichia coli

    PubMed Central

    Butler, Emily K.; Tan, Wee Boon; Joseph, Hildy

    2014-01-01

    Peptidoglycan (PG) is an extracytoplasmic glycopeptide matrix essential for the integrity of the envelope of most bacteria. The PG building block is a disaccharide-pentapeptide that is synthesized as a lipid-linked precursor called lipid II. The translocation of the amphipathic lipid II across the cytoplasmic membrane is required for subsequent incorporation of the disaccharide-pentapeptide into PG. In Escherichia coli, the essential inner membrane protein MurJ is the lipid II flippase. Previous studies showed that 8 charged residues in the central cavity region of MurJ are crucial for function. Here, we completed the functional analysis of all 57 charged residues in MurJ and demonstrated that the respective positive or negative charge of the 8 aforementioned residues is required for proper MurJ function. Loss of the negative charge in one of these residues, D39, causes a severe defect in MurJ biogenesis; by engineering an intragenic suppressor mutation that restores MurJ biogenesis, we found that this charge is also essential for MurJ function. Because of the low level of homology between MurJ and putative orthologs from Gram-positive bacteria, we explored the conservation of these 8 charged residues in YtgP, a homolog from Streptococcus pyogenes. We found that only 3 positive charges are similarly positioned and essential in YtgP; YtgP possesses additional charged residues within its predicted cavity that are essential for function and conserved among Gram-positive bacteria. From these data, we hypothesize that some charged residues in the cavity region of MurJ homologs are required for interaction with lipid II and/or energy coupling during transport. PMID:25225268

  1. Charge requirements of lipid II flippase activity in Escherichia coli.

    PubMed

    Butler, Emily K; Tan, Wee Boon; Joseph, Hildy; Ruiz, Natividad

    2014-12-01

    Peptidoglycan (PG) is an extracytoplasmic glycopeptide matrix essential for the integrity of the envelope of most bacteria. The PG building block is a disaccharide-pentapeptide that is synthesized as a lipid-linked precursor called lipid II. The translocation of the amphipathic lipid II across the cytoplasmic membrane is required for subsequent incorporation of the disaccharide-pentapeptide into PG. In Escherichia coli, the essential inner membrane protein MurJ is the lipid II flippase. Previous studies showed that 8 charged residues in the central cavity region of MurJ are crucial for function. Here, we completed the functional analysis of all 57 charged residues in MurJ and demonstrated that the respective positive or negative charge of the 8 aforementioned residues is required for proper MurJ function. Loss of the negative charge in one of these residues, D39, causes a severe defect in MurJ biogenesis; by engineering an intragenic suppressor mutation that restores MurJ biogenesis, we found that this charge is also essential for MurJ function. Because of the low level of homology between MurJ and putative orthologs from Gram-positive bacteria, we explored the conservation of these 8 charged residues in YtgP, a homolog from Streptococcus pyogenes. We found that only 3 positive charges are similarly positioned and essential in YtgP; YtgP possesses additional charged residues within its predicted cavity that are essential for function and conserved among Gram-positive bacteria. From these data, we hypothesize that some charged residues in the cavity region of MurJ homologs are required for interaction with lipid II and/or energy coupling during transport. PMID:25225268

  2. Soil erosion and sediment control laws. A review of state laws and their natural resource data requirements

    NASA Technical Reports Server (NTRS)

    Klein, S. B.

    1980-01-01

    Twenty states, the District of Columbia, and the Virgin Islands enacted erosion and sediment control legislation during the past decade to provide for the implementation or the strengthening of statewide erosion and sediment control plans for rural and/or urban lands. That legislation and the state programs developed to implement these laws are quoted and reviewed. The natural resource data requirements of each program are also extracted. The legislation includes amendments to conservation district laws, water quality laws, and erosion and sediment control laws. Laws which provides for legislative review of administrative regulations and LANDSAT applications and/or information systems that were involved in implementing or gathering data for a specific soil erosion and sediment control program are summarized as well as principal concerns affecting erosion and sediment control laws.

  3. Minimum Energy Requirements for Sustained Microbial Activity in Anoxic Sediments

    NASA Technical Reports Server (NTRS)

    Hoehler, Tori M.; Alperin, Marc J.; Albert, Daniel B.; Martens, Christoper S.; DeVincenzi, Donald L. (Technical Monitor)

    2000-01-01

    Currently understood mechanisms of biochemical energy conservation dictate that, in order to be biologically useful, energy must be available to organisms in "quanta" equal to, at minimum one-third to one-fifth of the energy required to synthesize ATP in vivo. The existence of this biological energy quantum means that a significant fraction of the chemical amp on Earth cannot be used to drive biological productivity, and places a fundamental thermodynamic constraint on the origins, evolution, and distribution of life. We examined the energy requirements of intact microbial assemblages in anoxic sediments from Cape Lookout Bight, NC, USA, using dissolved hydrogen concentrations as a non-invasive probe. In this system, the thermodynamics of metabolic processes occurring inside microbial cells is reflected quantitatively by H2 concentrations measured outside those cells. We find that methanogenic archaea are supported by energy yields as small as 10 kJ per mol, about half the quantity calculated from studies of microorganisms in culture. This finding implies that a significantly broader range of geologic and chemical niches might be exploited by microorganisms than would otherwise be expected.

  4. P-glycoprotein ATPase activity requires lipids to activate a switch at the first transmission interface.

    PubMed

    Loo, Tip W; Clarke, David M

    2016-04-01

    P-glycoprotein (P-gp) is an ABC (ATP-Binding Cassette) drug pump. A common feature of ABC proteins is that they are organized into two wings. Each wing contains a transmembrane domain (TMD) and a nucleotide-binding domain (NBD). Drug substrates and ATP bind at the interface between the TMDs and NBDs, respectively. Drug transport involves ATP-dependent conformational changes between inward- (open, NBDs far apart) and outward-facing (closed, NBDs close together) conformations. P-gps crystallized in the presence of detergent show an open structure. Human P-gp is inactive in detergent but basal ATPase activity is restored upon addition of lipids. The lipids might cause closure of the wings to bring the NBDs close together to allow ATP hydrolysis. We show however, that cross-linking the wings together did not activate ATPase activity when lipids were absent suggesting that lipids may induce other structural changes required for ATPase activity. We then tested the effect of lipids on disulfide cross-linking of mutants at the first transmission interface between intracellular loop 4 (TMD2) and NBD1. Mutants L443C/S909C and L443C/R905C but not G471C/S909C and V472C/S909C were cross-linked with oxidant when in membranes. The mutants were then purified and cross-linked with or without lipids. Mutants G471C/S909C and V472C/S909C cross-linked only in the absence of lipids whereas mutants L443C/S909C and L443C/R905C were cross-linked only in the presence of lipids. The results suggest that lipids activate a switch at the first transmission interface and that the structure of P-gp is different in detergents and lipids. PMID:26944019

  5. 34 CFR 694.21 - What are required activities for GEAR UP projects?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 4 2011-07-01 2011-07-01 false What are required activities for GEAR UP projects? 694... READINESS FOR UNDERGRADUATE PROGRAMS (GEAR UP) § 694.21 What are required activities for GEAR UP projects? A... in the GEAR UP program. These services must include the following activities: (a)...

  6. 34 CFR 694.21 - What are required activities for GEAR UP projects?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 4 2014-07-01 2014-07-01 false What are required activities for GEAR UP projects? 694... READINESS FOR UNDERGRADUATE PROGRAMS (GEAR UP) § 694.21 What are required activities for GEAR UP projects? A... in the GEAR UP program. These services must include the following activities: (a)...

  7. 34 CFR 694.21 - What are required activities for GEAR UP projects?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 4 2012-07-01 2012-07-01 false What are required activities for GEAR UP projects? 694... READINESS FOR UNDERGRADUATE PROGRAMS (GEAR UP) § 694.21 What are required activities for GEAR UP projects? A... in the GEAR UP program. These services must include the following activities: (a)...

  8. 34 CFR 694.21 - What are required activities for GEAR UP projects?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 4 2013-07-01 2013-07-01 false What are required activities for GEAR UP projects? 694... READINESS FOR UNDERGRADUATE PROGRAMS (GEAR UP) § 694.21 What are required activities for GEAR UP projects? A... in the GEAR UP program. These services must include the following activities: (a)...

  9. Understanding How Resources and Capabilities Affect Performance: Actively Applying the Resource-Based View in the Classroom

    ERIC Educational Resources Information Center

    Sheehan, Norman T.

    2006-01-01

    The resource-based view is a strategic framework for understanding why some firms outperform others. Its importance is reflected in its wide inclusion in strategy texts as a tool for assessing a firm's internal strengths and weaknesses. This article outlines an experiential exercise that demonstrates how different bundles of resources and…

  10. Fungal cellulase is an elicitor but its enzymatic activity is not required for its elicitor activity.

    PubMed

    Ma, Yanan; Han, Chao; Chen, Jinyin; Li, Haiyun; He, Kun; Liu, Aixin; Li, Duochuan

    2015-01-01

    Plant-pathogenic fungi produce cellulases. However, little information is available on cellulase as an elicitor in plant-pathogen interactions. Here, an endocellulase (EG1) was isolated from Rhizoctonia solani. It contains a putative protein of 227 amino acids with a signal peptide and a family-45 glycosyl hydrolase domain. Its aspartic acid (Asp) residue at position 32 was changed to alanine (Ala), resulting in full loss of its catalytic activity. Wild-type and mutated forms of the endoglucanase were expressed in yeast and purified to homogeneity. The purified wild-type and mutant forms induced cell death in maize, tobacco and Arabidopsis leaves, and the transcription of three defence marker genes in maize and tobacco and 10 genes related to defence responses in maize. Moreover, they also induced the accumulation of reactive oxygen species (ROS), medium alkalinization, Ca(2+) accumulation and ethylene biosynthesis of suspension-cultured tobacco cells. Similarly, production of the EG1 wild-type and mutated forms in tobacco induced cell death using the Potato virus X (PVX) expression system. In vivo, expression of EG1 was also related to cell death during infection of maize by R. solani. These results provide direct evidence that the endoglucanase is an elicitor, but its enzymatic activity is not required for its elicitor activity. PMID:24844544

  11. The availability of attentional resources modulates the inhibitory strength related to weakly activated priming.

    PubMed

    Wang, Yongchun; Wang, Yonghui; Liu, Peng; Dai, Dongyang; Di, Meilin; Chen, Qiang

    2016-08-01

    The current study investigated the role of attention in inhibitory processes (the inhibitory processes described in the current study refer only to those associated with masked or flanked priming) using a mixed paradigm involving the negative compatibility effect (NCE) and object-based attention. Accumulating evidence suggests that attention can be spread more easily within the same object, which increases the availability of attentional resources, than across different objects. Accordingly, we manipulated distractor location (with primes presented in the same object versus presented in different objects) together with prime/target compatibility (compatible versus incompatible) and prime-distractor stimulus onset asynchrony (SOA, 23 ms vs 70 ms). The aim was to investigate whether inhibitory processes related to weakly activated priming, which have been previously assumed to be automatic, depend on the availability of attentional resources. The results of Experiment 1 showed a significant NCE for the 70-ms SOA when the prime and distractor were presented in the same object (greater attentional resource availability); however, reversed NCEs were obtained for all other conditions. Experiment 2 was designed to disentangle whether the results of Experiment 1 were affected by the prime position, and the results indicated that the prime position did not modulate the NCE in Experiment 1. Together, these results are consistent with the claim that the availability of attentional resources modulates the inhibitory strength related to weakly activated priming. Specifically, if attentional resources are assigned to the distractor when it is presented in the same object as the prime, the strength of the inhibition elicited by the distractor may increase and reverse the activation elicited by the prime, which could lead to a significant NCE. PMID:27198916

  12. United States data collection activities and requirements, volume 1

    NASA Technical Reports Server (NTRS)

    Hrin, S.; Mcgregor, D.

    1977-01-01

    The potential market for a data collection system was investigated to determine whether the user needs would be sufficient to support a satellite relay data collection system design. The activities of 107,407 data collections stations were studied to determine user needs in agriculture, climatology, environmental monitoring, forestry, geology, hydrology, meteorology, and oceanography. Descriptions of 50 distinct data collections networks are described and used to form the user data base. The computer program used to analyze the station data base is discussed, and results of the analysis are presented in maps and graphs. Information format and coding is described in the appendix.

  13. Sphingosine Kinase Activity Is Not Required for Tumor Cell Viability

    PubMed Central

    Brown, Matthew L.; Carlson, Timothy; Coxon, Angela; Fajardo, Flordeliza; Frank, Brendon; Gustin, Darin; Kamb, Alexander; Kassner, Paul D.; Li, Shyun; Li, Yihong; Morgenstern, Kurt; Plant, Matthew; Quon, Kim; Ruefli-Brasse, Astrid; Schmidt, Joanna; Swearingen, Elissa; Walker, Nigel; Wang, Zhulun; Watson, J. E. Vivienne; Wickramasinghe, Dineli; Wong, Mariwil; Xu, Guifen; Wesche, Holger

    2013-01-01

    Sphingosine kinases (SPHKs) are enzymes that phosphorylate the lipid sphingosine, leading to the formation of sphingosine-1-phosphate (S1P). In addition to the well established role of extracellular S1P as a mitogen and potent chemoattractant, SPHK activity has been postulated to be an important intracellular regulator of apoptosis. According to the proposed rheostat theory, SPHK activity shifts the intracellular balance from the pro-apoptotic sphingolipids ceramide and sphingosine to the mitogenic S1P, thereby determining the susceptibility of a cell to apoptotic stress. Despite numerous publications with supporting evidence, a clear experimental confirmation of the impact of this mechanism on tumor cell viability in vitro and in vivo has been hampered by the lack of suitable tool reagents. Utilizing a structure based design approach, we developed potent and specific SPHK1/2 inhibitors. These compounds completely inhibited intracellular S1P production in human cells and attenuated vascular permeability in mice, but did not lead to reduced tumor cell growth in vitro or in vivo. In addition, siRNA experiments targeting either SPHK1 or SPHK2 in a large panel of cell lines failed to demonstrate any statistically significant effects on cell viability. These results show that the SPHK rheostat does not play a major role in tumor cell viability, and that SPHKs might not be attractive targets for pharmacological intervention in the area of oncology. PMID:23861887

  14. Glucagon and adenylate cyclase: binding studies and requirements for activation.

    PubMed

    Levey, G S; Fletcher, M A; Klein, I

    1975-01-01

    Solubilization of myocardial adenylate cyclase abolished responsiveness to glucagon and catecholamines, two of the hormones which activate the membrane-bound enzyme. Adenylate cyclase freed of detergent by DEAE-cellulose chromatography continues to remain unresponsive to hormone stimulation. However, adding purified bovine brain phospholipids--phosphotidylserine and monophosphatidylinositol--restored responsiveness to glucagon and catecholamines, respectively. 125-i-glucagon binding appeared to be independent of phospholipid, since equal binding was observed in the presence or absence of detergent and in the presence or absence of phospholipids. Chromatography of the solubilized preparation on Sephadex G-100 WAS CHARACTERIZED BY 125-I-glucagon binding and fluoride-stimulatable adenylate cyclase activity appearing in the fractions consistent with the void volume, suggesting a molecular weight greater than 100,000 for the receptor-adenylate cyclase complex. Prior incubation of the binding peak with 125-I-glucagon and rechromatography of the bound glucagon on Sephadex G-100 shifted its elution to a later fraction consistent with a smaller-molecular-weight peak. The molecular weight of this material was 24,000 to 28,000, as determined by SDS polyacrylamide gel electrophoresis. The latter findings are consistent with a dissociable receptor site for glucagon on myocardial adenylate cyclase. PMID:165684

  15. El Universo a Sus Pies: Actividades y Recursos para Astronomia (Universe at Your Fingertips: An Astronomy Activity and Resource Notebook).

    ERIC Educational Resources Information Center

    Fraknoi, Andrew, Ed.; Schatz, Dennis, Ed.

    The goal of this resource notebook is to provide activities selected by astronomers and classroom teachers, comprehensive resource lists and bibliographies, background material on astronomical topics, and teaching ideas from experienced astronomy educators. Activities are grouped into several major areas of study in astronomy including lunar…

  16. NASA Propulsion Sub-System Concept Studies and Risk Reduction Activities for Resource Prospector Lander

    NASA Technical Reports Server (NTRS)

    Trinh, Huu P.

    2015-01-01

    NASA's exploration roadmap is focused on developing technologies and performing precursor missions to advance the state of the art for eventual human missions to Mars. One of the key components of this roadmap is various robotic missions to Near-Earth Objects, the Moon, and Mars to fill in some of the strategic knowledge gaps. The Resource Prospector (RP) project is one of these robotic precursor activities in the roadmap. RP is a multi-center and multi-institution project to investigate the polar regions of the Moon in search of volatiles. The mission is rated Class D and is approximately 10 days, assuming a five day direct Earth to Moon transfer. Because of the mission cost constraint, a trade study of the propulsion concepts was conducted with a focus on available low-cost hardware for reducing cost in development, while technical risk, system mass, and technology advancement requirements were also taken into consideration. The propulsion system for the lander is composed of a braking stage providing a high thrust to match the lander's velocity with the lunar surface and a lander stage performing the final lunar descent. For the braking stage, liquid oxygen (LOX) and liquid methane (LCH4) propulsion systems, derived from the Morpheus experimental lander, and storable bi-propellant systems, including the 4th stage Peacekeeper (PK) propulsion components and Space Shuttle orbital maneuvering engine (OME), and a solid motor were considered for the study. For the lander stage, the trade study included miniaturized Divert Attitude Control System (DACS) thrusters (Missile Defense Agency (MDA) heritage), their enhanced thruster versions, ISE-100 and ISE-5, and commercial-off-the-shelf (COTS) hardware. The lowest cost configuration of using the solid motor and the PK components while meeting the requirements was selected. The reference concept of the lander is shown in Figure 1. In the current reference configuration, the solid stage is the primary provider of delta

  17. Highly porous activated carbons from resource-recovered Leucaena leucocephala wood as capacitive deionization electrodes.

    PubMed

    Hou, Chia-Hung; Liu, Nei-Ling; Hsi, Hsing-Cheng

    2015-12-01

    Highly porous activated carbons were resource-recovered from Leucaena leucocephala (Lam.) de Wit. wood through combined chemical and physical activation (i.e., KOH etching followed by CO2 activation). This invasive species, which has severely damaged the ecological economics of Taiwan, was used as the precursor for producing high-quality carbonaceous electrodes for capacitive deionization (CDI). Carbonization and activation conditions strongly influenced the structure of chars and activated carbons. The total surface area and pore volume of activated carbons increased with increasing KOH/char ratio and activation time. Overgasification induced a substantial amount of mesopores in the activated carbons. In addition, the electrochemical properties and CDI electrosorptive performance of the activated carbons were evaluated; cyclic voltammetry and galvanostatic charge/discharge measurements revealed a typical capacitive behavior and electrical double layer formation, confirming ion electrosorption in the porous structure. The activated-carbon electrode, which possessed high surface area and both mesopores and micropores, exhibited improved capacitor characteristics and high electrosorptive performance. Highly porous activated carbons derived from waste L. leucocephala were demonstrated to be suitable CDI electrode materials. PMID:26135977

  18. Implications of climatic seasonality on activity patterns and resource use by sympatric peccaries in northern Pantanal

    NASA Astrophysics Data System (ADS)

    Hofmann, Gabriel Selbach; Coelho, Igor Pfeifer; Bastazini, Vinicius Augusto Galvão; Cordeiro, José Luís Passos; de Oliveira, Luiz Flamarion Barbosa

    2016-03-01

    We evaluated the effects of climate seasonality from a thermal and water availability perspective on the activity patterns and resource use of Pecari tajacu and Tayassu pecari during wet and dry seasons in the northeastern Brazilian Pantanal. We used camera traps and temperature sensors to record species activity patterns in relation to temperature, established five habitat categories based on flooding intensity and local vegetation characteristics, assessed the activity patterns of each species in dry and wet periods and in artificial water bodies using circular statistical metrics, and calculated niche amplitude and overlap on three axes (temperature, time, and habitat) in both periods. Peccaries shared a strong resemblance in resource use and in their responses to seasonal variations in the tested gradients. The activity patterns of both species exhibited a significant correlation with air temperature on all the evaluated measures, and both species strongly reduced their activity when the air temperature exceeded 35 °C. High temperatures associated with low water availability were most likely responsible for the changes in species activity patterns, which resulted in an increased temporal overlap in habitat use throughout the dry season. However, the peccaries avoided intensively flooded habitats; therefore, the habitat gradient overlap was greater during the wet period. Our results show that an increase in niche overlap on the environmental gradient as a result of climatic seasonality may be partially compensated by a reduction in other niche dimensions. In this case, temporal partitioning appears to be an important, viable mechanism to reduce competition by potentially competing species.

  19. Summary. [California activities in remote sensing and management of water resources

    NASA Technical Reports Server (NTRS)

    Colwell, R. N.

    1973-01-01

    University of California activities in the development of remote sensing techniques and their application in the study of water resources within the state are summarized. It is pointed out that the summary is very lengthy due to fact that NASA had requested a dramatic reorientation of the study. For this reason it was felt that the co-investigators and other participants, need a rather detailed and systematic tabulation of the relevant facts that have been uncovered during the period since the reorientation.

  20. [Biological activities of natural resources around us are now in the limelight].

    PubMed

    Takaya, Y

    2000-11-01

    There are various kind of natural resources around us, and they must contain a lot of unknown bioactive substances. Some may be structurally very strange for us, and some are very familiar. But their biological activity was not unfortunately investigated in detail. Accordingly, exploring new types of pharmaceutical resources may give lead compounds of the drugs in the future. Among those natural resources, I examined squid ink and scallop soup. From squid ink, an antitumor glycoconjugate was obtained. Its polysaccharide moieties, illexin A, illexin B and illexin C, were isolated, and the spectral data and chemical transformation of their acid hydrolysate revealed to bear a unique branched repeating unit, [-3GlcA beta 1-4(GalNAc alpha 1-3)Fuc alpha 1-]n. Moreover, scallop soup gave antitumor glycogen by the action of protease. The fine structure of glycogen was investigated by the sequential enzyme digestion method using beta-amylase and pullulanase, while the unit chain was analyzed by high performance anion exchange chromatography. The results showed that the antitumor active glycogen was highly branched with shorter chain than glycogens without antitumor activity. PMID:11190195

  1. Activation of STING requires palmitoylation at the Golgi

    PubMed Central

    Mukai, Kojiro; Konno, Hiroyasu; Akiba, Tatsuya; Uemura, Takefumi; Waguri, Satoshi; Kobayashi, Toshihide; Barber, Glen N.; Arai, Hiroyuki; Taguchi, Tomohiko

    2016-01-01

    Stimulator of interferon genes (STING) is essential for the type I interferon response against DNA pathogens. In response to the presence of DNA and/or cyclic dinucleotides, STING translocates from the endoplasmic reticulum to perinuclear compartments. However, the role of this subcellular translocation remains poorly defined. Here we show that palmitoylation of STING at the Golgi is essential for activation of STING. Treatment with palmitoylation inhibitor 2-bromopalmitate (2-BP) suppresses palmitoylation of STING and abolishes the type I interferon response. Mutation of two membrane-proximal Cys residues (Cys88/91) suppresses palmitoylation, and this STING mutant cannot induce STING-dependent host defense genes. STING variants that constitutively induce the type I interferon response were found in patients with autoimmune diseases. The response elicited by these STING variants is effectively inhibited by 2-BP or an introduction of Cys88/91Ser mutation. Our results may lead to new treatments for cytosolic DNA-triggered autoinflammatory diseases. PMID:27324217

  2. Activation of STING requires palmitoylation at the Golgi.

    PubMed

    Mukai, Kojiro; Konno, Hiroyasu; Akiba, Tatsuya; Uemura, Takefumi; Waguri, Satoshi; Kobayashi, Toshihide; Barber, Glen N; Arai, Hiroyuki; Taguchi, Tomohiko

    2016-01-01

    Stimulator of interferon genes (STING) is essential for the type I interferon response against DNA pathogens. In response to the presence of DNA and/or cyclic dinucleotides, STING translocates from the endoplasmic reticulum to perinuclear compartments. However, the role of this subcellular translocation remains poorly defined. Here we show that palmitoylation of STING at the Golgi is essential for activation of STING. Treatment with palmitoylation inhibitor 2-bromopalmitate (2-BP) suppresses palmitoylation of STING and abolishes the type I interferon response. Mutation of two membrane-proximal Cys residues (Cys88/91) suppresses palmitoylation, and this STING mutant cannot induce STING-dependent host defense genes. STING variants that constitutively induce the type I interferon response were found in patients with autoimmune diseases. The response elicited by these STING variants is effectively inhibited by 2-BP or an introduction of Cys88/91Ser mutation. Our results may lead to new treatments for cytosolic DNA-triggered autoinflammatory diseases. PMID:27324217

  3. Activation of AMP-kinase by Policosanol Requires Peroxisomal Metabolism

    PubMed Central

    Banerjee, Subhashis; Ghoshal, Sarbani

    2011-01-01

    Policosanol, a well-defined mixture of very long chain primary alcohols that is available as a nutraceutical product, has been reported to lower blood cholesterol levels. The present studies demonstrate that policosanol promotes the phosphorylation of AMP-kinase and HMG-CoA reductase in hepatoma cells and in mouse liver after intragastric administration, providing a possible means by which policosanol might lower blood cholesterol levels. Treatment of hepatoma cells with policosanol produced a 2.5-fold or greater increase in the phosphorylation of AMP-kinase and HMG-CoA reductase, and increased the phosphorylation of Ca++/calmodulin-dependent kinase kinase (CaMKK), an upstream AMP-kinase kinase. Intra-gastric administration of policosanol to mice similarly increased the phosphorylation of hepatic HMG-CoA reductase and AMP-kinase by greater than 2-fold. siRNA-mediated suppression of fatty aldehyde dehydrogenase, fatty acyl-CoA synthetase 4, and acyl-CoA acetyltransferase expression in hepatoma cells prevented the phosphorylation of AMP-kinase and HMG-CoA reductase by policosanol, indicating that metabolism of these very long chain alcohols to activated fatty acids is necessary for the suppression of cholesterol synthesis, presumably by increasing cellular AMP levels. Subsequent peroxisomal β-oxidation probably augments this effect. PMID:21359855

  4. Application of the MIKE SHE hydrological model in exploring sustainable development of water resources for agricultural activities in the White Volta Basin, Ghana

    NASA Astrophysics Data System (ADS)

    Oteng, F. M.; Alo, C. A.; Bitew, M. M.; Yidana, S. M.

    2013-12-01

    Sustainable abstraction of groundwater resources for commercial irrigation in the White Volta Basin (WVB) holds promise for a fledging agricultural industry in the basin. This is because erratic rainfall patterns attending climate change/variability has imposed mixed fortunes in terms of rain-fed agricultural activities currently practiced in the WVB. Addressing the sustainability of groundwater for commercial abstraction will require the integration of surface and subsurface flows and analysis of the impacts of climate change scenarios on the resource, employing a surface-subsurface flow model. Here, we present early results from surface flow simulation over the basin using the physically-based surface-subsurface flow model MIKE SHE.

  5. Physical Activity Resources and Changes in Walking in a Cohort of Older Men

    PubMed Central

    Perdue, Leslie A.; Orwoll, Eric S.; Stefanick, Marcia L.; Marshall, Lynn M.

    2010-01-01

    Objectives. We evaluated the influence of physical activity resources and neighborhood-level socioeconomic status (SES) on walking among community-dwelling older men. Methods. Participants reported time walked per day at baseline (2000–2002) and follow-up. Residential addresses were linked to a geographic information system database to assess proximity to parks, trails, and recreational facilities. Log-binomial regression analyses were conducted to test the hypothesis that men living near physical activity resources were more likely to increase or maintain time walked. Results. Average time walked per day declined by 6 minutes between baseline and follow-up (P < .05). There was a significant interaction of neighborhood SES and physical activity with walking time (P < .1). Proximity to parks and proximity to trails, respectively, were associated with a 22% (95% confidence interval [CI] = 1.01, 1.47) and 34% (95% CI = 1.16, 1.55) higher likelihood of maintaining or increasing walking time in high-SES neighborhoods, but there was no association in low-SES neighborhoods. Proximity to recreational facilities was not associated with walking. Conclusions. Uncovering reasons that proximity to parks and trails is not associated with maintenance of walking activity among men in low-SES neighborhoods could provide new insight into ways to promote physical activity. PMID:20167887

  6. Comparative analysis on the distribution of protease activities among fruits and vegetable resources.

    PubMed

    Sun, Qian; Zhang, Bin; Yan, Qiao-Juan; Jiang, Zheng-Qiang

    2016-12-15

    In this study, a comparative analysis on the distribution of protease activities among 90 plant resources, including fruits and vegetables, has been performed. Protease activities of plant extracts were assayed at different pH values (pH 3.0, pH 7.5 and pH 10.5) using casein as a substrate. Ten fruits and thirteen vegetables show protease activities above 10U/g. Pineapple, fig and papaya, which are used for commercial protease production, exhibited high protease activities. Additionally, high protease activities were detected in kiwifruit (28.8U/g), broccoli (16.9U/g), ginger (16.6U/g), leek (32.7U/g) and red pepper (15.8U/g) at different pH values. SDS-PAGE and zymograms confirmed that various types of proteases existed in the five plant extracts and might be explored. Furthermore, five plant extracts were treated by different protease inhibitors. These results show that there are still many plant resources unexplored, which may be promising candidates for plant-derived protease production. PMID:27451238

  7. 38 CFR 3.12a - Minimum active-duty service requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Minimum active-duty... Minimum active-duty service requirement. (a) Definitions. (1) The term minimum period of active duty means... continuous active duty. Non-duty periods that are excludable in determining the Department of...

  8. The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics.

    PubMed

    Cantarel, Brandi L; Coutinho, Pedro M; Rancurel, Corinne; Bernard, Thomas; Lombard, Vincent; Henrissat, Bernard

    2009-01-01

    The Carbohydrate-Active Enzyme (CAZy) database is a knowledge-based resource specialized in the enzymes that build and breakdown complex carbohydrates and glycoconjugates. As of September 2008, the database describes the present knowledge on 113 glycoside hydrolase, 91 glycosyltransferase, 19 polysaccharide lyase, 15 carbohydrate esterase and 52 carbohydrate-binding module families. These families are created based on experimentally characterized proteins and are populated by sequences from public databases with significant similarity. Protein biochemical information is continuously curated based on the available literature and structural information. Over 6400 proteins have assigned EC numbers and 700 proteins have a PDB structure. The classification (i) reflects the structural features of these enzymes better than their sole substrate specificity, (ii) helps to reveal the evolutionary relationships between these enzymes and (iii) provides a convenient framework to understand mechanistic properties. This resource has been available for over 10 years to the scientific community, contributing to information dissemination and providing a transversal nomenclature to glycobiologists. More recently, this resource has been used to improve the quality of functional predictions of a number genome projects by providing expert annotation. The CAZy resource resides at URL: http://www.cazy.org/. PMID:18838391

  9. The legal regime for moon resource utilization and comparable solutions adopted for deep seabed activities

    NASA Astrophysics Data System (ADS)

    Viikari, L. E.

    2003-06-01

    The Moon and the deep seabed (including their natural resources) are the only environs in international law explicitly proclaimed as the common heritage of mankind. This would seem to necessitate a specific approach to the utilization of their natural resources, too, but this must be one that takes into account the fact that both domains are increasingly affected by commercialization and privatization. The premise of this paper is that a productive analogy can be drawn between the regulation of activities in these two areas, one that benefits space law in particular. The only directly relevant space treaty in this regard, the so-called Moon Treaty of 1979, was drafted in a quite different world; moreover, only 10 countries have ratified the Treaty, and none of these can be considered a major space faring nation. The law of the sea has been far more successful in solving such problems in its area than space law has in its own. Particularly noteworthy are the innovative amendments to the 1982 UN Convention on the Law of the Sea, which were able to accommodate the concerns of the industrialized states and could thus yield guidelines for the future development of the law of outer space where natural resource utilization is concerned. While utilization of the resources of celestial bodies of course mostly still lies ahead, the increasing pace in the development of human space activities suggests that now would be an ideal time to make legal rules governing the activities, which may be a reality sooner than we can ever expect.

  10. Do Neighborhood Physical Activity Resources and Land Use Influence Physical Activity among African American Public Housing Residents?

    PubMed

    Parker, Nathan H; O'Connor, Daniel P; Kao, Dennis T; Lee, Rebecca E

    2016-01-01

    Few studies have examined neighborhood influences on physical activity (PA) among low-income African Americans living in public housing. This study measured the associations of PA resources and land use with PA among 216 African Americans living in 12 low-income housing developments in Houston, Texas. Neighborhood measures included both detailed information from in-person audits and geographic information systems (GIS) data. Hierarchical linear regression models tested the associations of neighborhood PA resource availability and quality and land use density and diversity with individual-level, self-reported PA. Land use diversity was positively associated with walking among men after controlling for other neighborhood characteristics. Policies that promote land use diversity or improve the pedestrian environment in areas with diverse destinations may encourage PA among public housing residents. PMID:27524771

  11. A Survey of Educational Activities and Resources Relevant to Mars and Astrobiology

    NASA Astrophysics Data System (ADS)

    Manning, Heidi L. K.; Bleacher, L.

    2009-09-01

    Sample Analysis at Mars (SAM) is a suite of instruments that will be onboard the Mars Science Laboratory (MSL) rover, which was recently named Curiosity in a student-naming contest. SAM's three instruments are devoted to studying the chemical composition of the Martian surface and atmosphere and to understanding the planet's past habitability and potential habitability today. Curiosity is scheduled to launch in 2011, however many Education and Public Outreach (EPO) activities supported by the MSL mission are well underway. The SAM EPO plan includes elements of both formal and informal education in addition to outreach, such as incorporating data into the Mars Exploration Student Data Teams program, developing a museum exhibit and associated educational materials about SAM's research, and writing articles about the MSL mission and SAM's findings for ChemMatters magazine. One of the EPO projects currently being carried out by members of the SAM team is training secondary education teachers in Mars geology, astrobiology, and SAM science goals via professional development workshops. Several of the recent Mars missions have had extensive EPO components to them. As a result, numerous educational activities and resources have already been developed relating to understanding Mars and astrobiology. We have conducted a survey of these activities and resources previously created and have compiled those relevant and useful for our SAM teacher training workshops. Resources and activities have been modified as needed. In addition, we have identified areas in which no educational activities exist and are developing new curriculum specifically to address these gaps. This work is funded by the MN Space Grant Consortium and NASA's Science Mission Directorate.

  12. 24 CFR 1000.240 - When is a local cooperation agreement required for affordable housing activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false When is a local cooperation... ACTIVITIES Indian Housing Plan (IHP) § 1000.240 When is a local cooperation agreement required for affordable housing activities? The requirement for a local cooperation agreement applies only to rental and...

  13. 10 CFR 420.15 - Minimum criteria for required program activities for plans.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Minimum criteria for required program activities for plans. 420.15 Section 420.15 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION STATE ENERGY PROGRAM Formula Grant Procedures § 420.15 Minimum criteria for required program activities for plans. A plan shall satisfy all of the following minimum criteria...

  14. 20 CFR 404.1311 - Ninety-day active service requirement for World War II veterans.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... World War II veterans. 404.1311 Section 404.1311 Employees' Benefits SOCIAL SECURITY ADMINISTRATION... Uniformed Services World War II Veterans § 404.1311 Ninety-day active service requirement for World War II veterans. (a) The 90 days of active service required for World War II veterans do not have to...

  15. 20 CFR 404.1311 - Ninety-day active service requirement for World War II veterans.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... World War II veterans. 404.1311 Section 404.1311 Employees' Benefits SOCIAL SECURITY ADMINISTRATION... Uniformed Services World War II Veterans § 404.1311 Ninety-day active service requirement for World War II veterans. (a) The 90 days of active service required for World War II veterans do not have to...

  16. Converging on the optimal attainment of requirements

    NASA Technical Reports Server (NTRS)

    Feather, M. S.; Menzies, T.

    2002-01-01

    Planning for the optimal attainment of requirements is an important early lifecycle activity. However, such planning is difficult when dealing with competing requirements, limited resources, and the incompleteness of information available at requirements time.

  17. 10 CFR 73.50 - Requirements for physical protection of licensed activities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Requirements for physical protection of licensed activities. 73.50 Section 73.50 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) PHYSICAL PROTECTION OF PLANTS AND MATERIALS Physical Protection Requirements at Fixed Sites § 73.50 Requirements for...

  18. 10 CFR 73.50 - Requirements for physical protection of licensed activities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Requirements for physical protection of licensed activities. 73.50 Section 73.50 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) PHYSICAL PROTECTION OF PLANTS AND MATERIALS Physical Protection Requirements at Fixed Sites § 73.50 Requirements for...

  19. 10 CFR 73.50 - Requirements for physical protection of licensed activities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Requirements for physical protection of licensed activities. 73.50 Section 73.50 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) PHYSICAL PROTECTION OF PLANTS AND MATERIALS Physical Protection Requirements at Fixed Sites § 73.50 Requirements for...

  20. 10 CFR 73.50 - Requirements for physical protection of licensed activities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Requirements for physical protection of licensed activities. 73.50 Section 73.50 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) PHYSICAL PROTECTION OF PLANTS AND MATERIALS Physical Protection Requirements at Fixed Sites § 73.50 Requirements for...