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Sample records for activities st george

  1. 76 FR 79157 - Takes of Marine Mammals Incidental to Specified Activities; St. George Reef Light Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-21

    ...NMFS has received an application from the St. George Reef Lighthouse Preservation Society (SGRLPS), for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment incidental to conducting aircraft operations, lighthouse renovation, and light maintenance activities on the St. George Reef Light Station on Northwest Seal Rock (NWSR) in the northeast Pacific Ocean from the......

  2. 78 FR 1838 - Takes of Marine Mammals Incidental to Specified Activities; St. George Reef Light Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-09

    ...We have received an application from the St. George Reef Lighthouse Preservation Society (Society), for an Incidental Harassment Authorization (IHA) to take marine mammals, by harassment incidental to conducting aircraft operations, lighthouse renovation, and light maintenance activities on the St. George Reef Light Station on Northwest Seal Rock (NWSR) in the northeast Pacific Ocean from the......

  3. 75 FR 4774 - Takes of Marine Mammals Incidental to Specified Activities; St. George Reef Light Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-29

    ... Specified Activities; St. George Reef Light Station Restoration and Maintenance on Northwest Seal Rock, in... the St. George Reef Lighthouse Preservation Society (SGRLPS), to incidentally harass, by Level B... INFORMATION: Background Section 101(a)(5)(D) of the MMPA (16 U.S.C. 1371 (a)(5)(D)) directs the Secretary...

  4. 77 FR 8811 - Takes of Marine Mammals Incidental to Specified Activities; St. George Reef Light Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-15

    ...In accordance with the regulations implementing the Marine Mammal Protection Act (MMPA) as amended, notification is hereby given that NMFS has issued an Incidental Harassment Authorization (IHA) to the St. George Reef Lighthouse Preservation Society (SGRLPS) to take marine mammals, by Level B harassment only, incidental to conducting aircraft operations, and lighthouse renovation and light......

  5. 78 FR 71576 - Takes of Marine Mammals Incidental to Specified Activities; St. George Reef Light Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ...In accordance with the regulations implementing the Marine Mammal Protection Act (MMPA) as amended, notification is hereby given that we, NMFS, have issued an Incidental Harassment Authorization (Authorization) to the St. George Reef Lighthouse Preservation Society (Society) to take four species of marine mammals, by Level B harassment only, incidental to conducting helicopter operations, and......

  6. 27 CFR 9.51 - Isle St. George.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Isle St. George. 9.51... St. George. (a) Name. The name of the viticultural area described in this section is “Isle St. George.” (b) Approved maps. The approved map for determining the boundary of the Isle St. George...

  7. 27 CFR 9.51 - Isle St. George.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Isle St. George. 9.51... St. George. (a) Name. The name of the viticultural area described in this section is “Isle St. George.” (b) Approved maps. The approved map for determining the boundary of the Isle St. George...

  8. 27 CFR 9.51 - Isle St. George.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Isle St. George. 9.51... St. George. (a) Name. The name of the viticultural area described in this section is “Isle St. George.” (b) Approved maps. The approved map for determining the boundary of the Isle St. George...

  9. 27 CFR 9.51 - Isle St. George.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Isle St. George. 9.51... St. George. (a) Name. The name of the viticultural area described in this section is “Isle St. George.” (b) Approved maps. The approved map for determining the boundary of the Isle St. George...

  10. 27 CFR 9.51 - Isle St. George.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Isle St. George. 9.51... St. George. (a) Name. The name of the viticultural area described in this section is “Isle St. George.” (b) Approved maps. The approved map for determining the boundary of the Isle St. George...

  11. 76 FR 10564 - Takes of Marine Mammals Incidental to Specified Activities; St. George Reef Light Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-25

    ... notice for the proposed IHA (75 FR 80471 December 22, 2010). The planned activities have not changed... reader should refer to the proposed IHA notice (75 FR 8047, December 22, 2010). Comments and Responses... on December 22, 2010 (75 FR 80471). During the 30-day comment period, NMFS received a letter from...

  12. Moving towards first science with the St. George recoil separator

    NASA Astrophysics Data System (ADS)

    Meisel, Zachary; Berg, G. P. A.; Gilardy, G.; Moran, M.; Schmitt, J.; Seymour, C.; Stech, E.; Couder, M.

    2015-10-01

    The St. George recoil mass separator has recently been coupled to the 5MV St. Ana accelerator at the University of Notre Dame's Nuclear Science Lab. St. George is a unique tool designed to measure radiative alpha-capture reactions for nuclei up to A = 40 in inverse kinematics in order to directly obtain cross sections required for astrophysical models of stellar and explosive helium burning. Commissioning of St. George is presently taking place with primary beams of hydrogen, helium, and oxygen. In this presentation, results will be shown for the measured energy acceptance of St. George, which compare favorably to COSY results when employing the calculated optimal ion-optical settings. Additionally, future plans will be discussed, such as assessing the angular acceptance of St. George and the re-integration of HiPPO at the separator target position to provide a dense, windowless helium gas-jet target. The material presented in this work is partially supported by the National Science Foundation Grant No. 1419765.

  13. SEAFOOD PROCESSING PERMITTING, ALASKA - ST. GEORGE ISLAND - CHART #16381

    EPA Science Inventory

    St. George Island was digitized from NOAA Marine Chart #16381. Map details include ledge nesting seabirds, fur seal rookeries, fur seal and Steller sea lion haul out grounds, water depth and land. This map was created for EPA Region 10 Water Division to evaluate NPDES permit site...

  14. 77 FR 59035 - Notice of Intent To Rule on Request To Release Airport Property at the St. George Airport, St...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-25

    ... comment on the release of land at St. George Airport under the provisions of Section 125 of the Wendell H... request to release property at the St. George Airport under the provisions of the AIR 21 (49 U.S.C....

  15. 75 FR 21243 - Marine Mammals; Subsistence Taking of Northern Fur Seals; St. George

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ...: Northern Fur Seal St. George. Email comments with or without attachments are limited to 5 megabytes; Mail.... These regulations, which were promulgated by an emergency final rule in 1986 (51 FR 24828, July 9, 1986... Northern Fur Seals; St. George AGENCY: National Marine Fisheries Service (NMFS), National Oceanic...

  16. Latest quaternary volcanism in the St. George Basin, southwestern Utah

    SciTech Connect

    Millings, V.T. III; Green, J.D.; Nusbaum, R.L. . Dept. of Geology)

    1993-03-01

    The St. George Basin was the site of mafic volcanism from about 6 Ma to 1 ka. The nature of latest Quaternary volcanism is of interest because the Basin is recognized as a low temperature (< 90C) geothermal resource area and it is part of the transition zone between the Basin and Range Province and the Colorado Plateau. The authors have studied the geochemistry, mineralogy, and aerial distribution of two of the youngest eruptions centers: (1) Veyo Volcano; and (2) the Diamond Valley scoria cones (DVSC). Veyo Volcano erupted basaltic andesite, beginning with an explosive stage marked by a 0.5 m basal Plinian layer. Later eruptions alternated between quiescent and Strombolian-styles. Phenocrysts include clear plagioclase, sieve-texture plagioclase, olivine and rare augite. The DVSC and associated Santa Clara lava flow are tholeiitic basalt, consisting of olivine phenocrysts, and rare plagioclase phenocrysts. Based on preliminary geochemical data, Diamond Valley rocks exhibit lower incompatible element ratios compared to mafic rocks on the Markagunt Plateau and transition zone rocks. In contrast, Veyo Volcano rocks are similar to transition zone mafic rocks with regard to incompatible element abundances.

  17. COSY Simulations to Guide Commissioning of the St. George Recoil Mass Separator

    NASA Astrophysics Data System (ADS)

    Schmitt, Jaclyn; Moran, Michael; Seymour, Christopher; Gilardy, Gwenaelle; Meisel, Zach; Couder, Manoel

    2015-10-01

    The goal of St. George (STrong Gradient Electromagnetic Online Recoil separator for capture Gamma ray Experiments) is to measure (α, γ) cross sections relevant to stellar helium burning. Recoil separators such as St. George are able to more closely approach the low astrophysical energies of interest because they collect reaction recoils rather than γ-rays, and thus are not limited by room background. In order to obtain an accurate cross section measurement, a recoil separator must be able to collect all recoils over their full range of expected energy and angular spread. The energy acceptance of St. George is currently being measured, and the angular acceptance will be measured soon. Here we present the results of COSY ion optics simulations and magnetic field analyses which were performed to help guide the commissioning measurements and diagnostic upgrades required to complete those measurements. National Science Foundation Research Experiences for Undergraduates program.

  18. 33 CFR 334.650 - Gulf of Mexico, south of St. George Island, Fla.; test firing range.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Gulf of Mexico, south of St. George Island, Fla.; test firing range. 334.650 Section 334.650 Navigation and Navigable Waters CORPS OF....650 Gulf of Mexico, south of St. George Island, Fla.; test firing range. (a) The danger zone. A...

  19. 33 CFR 334.650 - Gulf of Mexico, south of St. George Island, Fla.; test firing range.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Gulf of Mexico, south of St. George Island, Fla.; test firing range. 334.650 Section 334.650 Navigation and Navigable Waters CORPS OF....650 Gulf of Mexico, south of St. George Island, Fla.; test firing range. (a) The danger zone. A...

  20. 33 CFR 334.650 - Gulf of Mexico, south of St. George Island, Fla.; test firing range.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Gulf of Mexico, south of St. George Island, Fla.; test firing range. 334.650 Section 334.650 Navigation and Navigable Waters CORPS OF....650 Gulf of Mexico, south of St. George Island, Fla.; test firing range. (a) The danger zone. A...

  1. 75 FR 62461 - Revocation and Establishment of Class E Airspace; St. George, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... Municipal Airport, St. George, UT (75 FR 44727). Interested parties were invited to participate in this... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p....

  2. 78 FR 45473 - Proposed Amendment of Class E Airspace; St. George, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-29

    ... 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71....) Within a 4.5-mile radius of St. George Municipal Airport. Issued in Seattle, Washington, on July 22,...

  3. 75 FR 44727 - Proposed Revocation and Establishment of Class E Airspace; St. George, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-29

    ... action also would establish Class E surface airspace within a 4.5-mile radius of the new St. George...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The incorporation...

  4. 33 CFR 334.650 - Gulf of Mexico, south of St. George Island, Fla.; test firing range.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Gulf of Mexico, south of St....650 Gulf of Mexico, south of St. George Island, Fla.; test firing range. (a) The danger zone. A fan... an arc with a 10,500 meter radius with its center located on the south shore line of St....

  5. 33 CFR 334.650 - Gulf of Mexico, south of St. George Island, Fla.; test firing range.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Gulf of Mexico, south of St....650 Gulf of Mexico, south of St. George Island, Fla.; test firing range. (a) The danger zone. A fan... an arc with a 10,500 meter radius with its center located on the south shore line of St....

  6. George Washington Bridge and stone abutment, from West 181st Street ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    George Washington Bridge and stone abutment, from West 181st Street and Riverside Drive overlook, looking west. HHP northbound, flanked by old Riverside Drive promenade (Hudson River Valley Greenway) with low masonry wall in center, and Fort Washington Park on right. Palisades Interstate Park across river in background. - Henry Hudson Parkway, Extending 11.2 miles from West 72nd Street to Bronx-Westchester border, New York County, NY

  7. St George's University's Medical Student Research Institute: A Novel, Virtual Programme for Medical Research Collaboration

    PubMed Central

    Chamberlain, RS; Klaassen, Z; Meadows, MC; Weitzman, S; Loukas, M

    2014-01-01

    Objective: Medical student research involvement has evolved to be a core component of medical education and is becoming increasingly vital to success in the United States residency match. We sought to develop a research website allowing students and research faculty to collaborate and complete projects online. Methods: The Medical Student Research Institute (MSRI) was developed by the St George's University School of Medicine in 2009 to encourage, support, facilitate and centralize medical student research. Results: There are 63 active students in the MSRI (22 students in basic science and 41 students in clinical rotations). The mean GPA for basic science student members was 3.81 ± 0.27 and was 3.80 ± 0.20 for clinical student members. The mean United States Medical Licensing Examination (USMLE) Step 1 score was 241.6 ± 17.5. Since 2009, MSRI students have published 87 manuscripts in 33 different journals and have presented at 14 different national and international conferences. Conclusion: A web-based MSRI provides a virtual, entirely online resource for coordinating remote research collaboration between medical students and faculty whose opportunities would be otherwise limited. Initial experiences with the programme have been positive and the framework and concept of the MSRI provides a platform for university and medical schools to provide research opportunities to students who may not have face-to-face access to research faculty. PMID:25303200

  8. Flood risk analysis model in the village of St. George/Danube Delta

    NASA Astrophysics Data System (ADS)

    Armas, I.; Dumitrascu, S.; Nistoran, D.

    2009-04-01

    the Danube Delta. The study area is situated at the mouth of the St. George river branch, which suffered a series of interventions resulting with the shortening with 31 km (period 1984-1988). As a direct result, the medium speed of the water grew along with the both liquid and solid flows. In fact, this is only an example of the human activity that took place in the Danube Delta starting with the second half of the last century that influenced the hydrological system for a better use of the natural resources offered by the delta. The study is structured in two stages: the analysis of the hydrological hazard together with the simulation of a series of scenarios concerning floods at various flows and the risk analysis, expressed in the shape of the calculus of the material damage. In the study of the hazard, the methodology was based on the analysis of water depth and velocity maps, done in various flow scenarios, to which were added correlations between flood risk maps with satellite pictures, cadastral plans and field data by using GIS functions. In addition, the field investigations conducted in September 2008 focused on collecting the data necessary in the assessment of the buildings. The observations that synthesize the features of each construction included in the analysis were also stored in ArcGis in the shape of a table of attributes. This information reveals the indicators used in the analysis of the vulnerability of the residences: number of floors, height, construction type, infrastructure and price per property. The analysis revealed an increased degree of the area visibility, pointing out not only certain sectors affected by floods, but also the problems that occurred at the more detailed level of the residences. In addition, the cartographic material plays also an important part in the development of a proper public awareness strategy.

  9. Petrology and Geochemistry of Plagioclase-Phyric Basaltic Lava Flows on St. George Island, Alaska: Evidence for a Genetic Link Between Magmatic Centers of the Pribilof Islands

    NASA Astrophysics Data System (ADS)

    Deraps, M. R.; Feeley, T. C.; Underwood, S. J.; Winer, G. S.

    2006-12-01

    St. George and St. Paul Islands, the two largest Pribilof Islands (Alaska), are located 70 km apart in the Bering Sea 400-450 km north of the Aleutian arc front. The islands are centers of alkaline basaltic volcanism associated with the diffuse Bering Sea basalt province. On St. George an extensive history of volcanism (~2.6-1.4 Ma; Mukasa and Andronikov, JGR, submitted) is exposed in high sea cliffs and several NE-SW and E-W trending fault blocks that define the present topography of the island. In contrast, St. Paul is a potentially active volcanic center (~550-3 ka) with numerous young tephra cones and associated lava flows that show minimal erosion and deformation by faulting. Volcanic rocks erupted on St. George are mainly olivine- + clinopyroxene-phyric basalts and trachy-basalts with high to moderate MgO contents (12-8 wt%). In addition, distinct plagioclase-phyric lavas are present at high stratigraphic levels. The plagioclase-phyric lavas are relatively evolved with 47-51 wt% SiO2 and 6.6-4.9 wt% MgO. Chondrite-normalized REE patterns are LREE-enriched with little to no Eu anomalies (Eu/Eu* = 1.03-1.06), indicating that the evolved compositions and plagioclase-rich nature of the flows are not due to phenocryst accumulation. Instead, production of plagioclase-phyric lavas on St. George likely involved a complex set of differentiation processes, including fractional crystallization and magma mixing. This assertion is supported by major and trace element compositions of the rocks, which define distinct trends on chemical variation diagrams relative to less evolved plagioclase-poor rocks. For example, whereas MgO contents of most St. George lavas as a group decrease with increasing SiO2 contents, these elements show a positive linear correlation for plagioclase-phyric lavas. The linear trends of these samples on chemical variation diagrams are best explained by mixing of at least two distinct evolved endmember magmas. Major element mass balance calculations

  10. Postgraduate training in public health medicine: St George's Hospital Medical School Library public health information service.

    PubMed

    Rook, R; Adshead, F

    2001-03-01

    This article examines the development of the St George's Hospital Medical School Library public health information service. Begun in 1997 as a pilot project to support Public Health Specialist Registrars in South Thames West, it is now an established part of postgraduate training in the region. An outline of the service is described, including the evolution of the post of Public Health Librarian. Issues influencing the development of the service, and the establishment of the Librarian as part of the public health network are discussed. This is a transferable model of public health information provision, which as a centralized resource makes best use of available funding. As a LIS model it is an effective and efficient way of maximizing resources, and delivering a service to a specialist user group that is spread across a wide geographical area. PMID:11260291

  11. Health-hazard evaluation report HETA 87-339-1863, St. Francis-St. George Hospital, Cincinnati, Ohio

    SciTech Connect

    Boiano, J.M.

    1988-01-01

    In response to a concern regarding lead exposure among health-care workers using lead-containing steam-sterilization indicators, an evaluation was made of exposures at the St. Francis-St. George Hospital, Cincinnati, Ohio. Steam-sterilization indicators used at the hospital (Surgicot indicator strips and tape and Tomac test records) contained appreciable amounts of lead that might be released by contact or during sterilization procedures. Personal-breathing-zone, area air, and surface wipe samples were taken and analyzed for lead content. No lead was detected in ten personal and general area air samples at a limit of 1.6 micrograms/cubic meter (microg/m/sup 3/), well below the OSHA Permissible Exposure Limit (50 microg/m/sup 3/). There was no evidence of elevated body burdens of lead in blood samples from nine technicians analyzed for lead and free-erythrocyte protoporphyrin. If the same lead-containing indicators are continued in use, no corrective action is needed. If other lead-containing steam sterilization indicators are put into service, testing should be done to determine if they pose a lead hazard to workers using them.

  12. Evolutionary trees and the rise of modern primatology: the forgotten contribution of St. George Mivart.

    PubMed

    Bigoni, Francesca; Barsanti, Giulio

    2011-01-01

    The modern concept of the tree of life originated as a popular, iconic synthesis of the Darwinian evolutionary theory of descent by modification even if Darwin's own trees were hypothetical and abstract. It is generally thought that Ernst Haeckel in 1866 was the first to publish a true evolutionary tree which showed actual taxa. It is apparently forgotten that St. George Mivart beginning in 1865 made significant contributions to the development of evolutionary based trees of life which dealt with primate evolution, including human phylogeny. His trees were built on the most extensive sets of original data published up to that time, and were clearly articulated as working hypotheses. Mivart's trees were surprisingly modern for appearance and for content. Not only are most taxonomic names still in use today, but also many of the issues he raised are still under discussion in current scientific literature. The history of biology and especially that of primatology in the 19th century can benefit from a more thorough knowledge of how the image of the tree was used in scientific writings, especially after Darwin in the context of the theory of evolution by descent from common ancestors. A reappraisal of Mivart's scientific achievements is necessary to better establish the origins and the development not only of evolutionary trees but of modern primatology. The history of primatology, a discipline that is fundamental for investigating the place of humans in nature, would also benefit from a reappraisal of Mivart's role in Victorian biology. PMID:21368345

  13. Geologic controls on the recent evolution of oyster reefs in Apalachicola Bay and St. George Sound, Florida

    NASA Astrophysics Data System (ADS)

    Twichell, D.; Edmiston, L.; Andrews, B.; Stevenson, W.; Donoghue, J.; Poore, R.; Osterman, L.

    2010-07-01

    Apalachicola Bay and St. George Sound contain the largest oyster fishery in Florida, and the growth and distribution of the numerous oyster reefs here are the combined product of modern estuarine conditions in the bay and its late Holocene evolution. Sidescan-sonar imagery, bathymetry, high-resolution seismic profiles, and sediment cores show that oyster beds occupy the crests of a series of shoals that range from 1 to 7 km in length, trend roughly north-south perpendicular to the long axes of the bay and sound, and are asymmetrical with steeper sides facing to the west. Surface sediment samples show that the oyster beds consist of shelly sand, while much of the remainder of the bay floor is covered by mud delivered by the Apalachicola River. The present oyster reefs rest on sandy delta systems that advanced southward across the region between 6400 and 4400 yr BP when sea level was 4-6 m lower than present. Oysters started to colonize the region around 5100 yr BP and became extensive by 1200 and 2400 yr BP. Since 1200 yr BP, their aerial extent has decreased due to burial of the edges of the reefs by the prodelta mud that continues to be supplied by the Apalachicola River. Oyster reefs that are still active are narrower than the original beds, have grown vertically, and become asymmetrical in cross-section. Their internal bedding indicates they have migrated westward, suggesting a net westerly transport of sediment in the bay.

  14. Biostratigraphic data for the Cretaceous marine sediments in the USGS-St. George no. 1 core (DOR-211), Dorchester County, South Carolina

    USGS Publications Warehouse

    Self-Trail, Jean M.; Gohn, Gregory S.

    1997-01-01

    The USGS-St. George corehole was drilled for the U.S. Geological Survey (USGS) by a commercial drilling company during 1982. The corehole is located within the Coastal Plain Province in northern Dorchester County, South Carolina, about three miles southeast of the town of St. George near the village of Byrd (fig. 1). Coordinates for the corehole are 33o09'25'N latitude and 80o31'18'W longitude; ground elevation at the site is +78 feet (Reid and others, 1986). The St. George corehole is designated as USGS drill hole DOR-211. The St. George corehole was drilled to a total depth of 2,067 ft. The hole was cored continuously with generally good recovery from 300 ft to its total depth. Spot cores were taken at selected intervals between the top of the hole and a depth of 300 ft (50-55 ft, 100-110 ft, 150-165 ft, 200-205 ft, and 250-255 ft); however, recovery was poor in most of these intervals. The St. George core currently is stored at the USGS National Center, Reston, VA (March, 1997). The St. George corehole bottomed in basalt of probable early Mesozoic age beneath an Upper Cretaceous and Cenozoic sedi-mentary section. Reid and others (1986) placed the top of basalt saprolite at 1,962 ft in the hole. Our examination of the geophysical logs and original core descriptions suggests that the top of the saprolite is higher in the hole, at about 1,939 ft. The Cretaceous-Tertiary boundary was placed at or near 550 ft in the core by Reid and others (1986) and by Habib and Miller (1989). In this report, we provide paleontologic data for marine sediments in the upper part of the Upper Cretaceous section in the St. George core. Biostratigraphic and paleoenvironmental data and interpretations based on the study of calcareous nannofossils and ostracodes from the Cretaceous section are discussed.

  15. Foraging segregation of two congeneric diving seabird species breeding on St. George Island, Bering Sea

    NASA Astrophysics Data System (ADS)

    Kokubun, Nobuo; Yamamoto, Takashi; Sato, Nobuhiko; Watanuki, Yutaka; Will, Alexis; Kitaysky, Alexander S.; Takahashi, Akinori

    2016-04-01

    Subarctic environmental changes are expected to affect the foraging ecology of marine top predators, but the response to such changes may vary among species if they use food resources differently. We examined the characteristics of foraging behavior of two sympatric congeneric diving seabird: common (Uria aalge: hereafter COMUs) and thick-billed (U. lomvia: hereafter TBMUs) murres breeding on St. George Island, located in the seasonal sea-ice region of the Bering Sea. We investigated their foraging trip and flight durations, diel patterns of dive depth, and underwater wing strokes, along with wing morphology and blood stable isotope signatures and stress hormones. Acceleration-temperature-depth loggers were attached to chick-guarding birds, and data were obtained from 7 COMUs and 12 TBMUs. Both species showed similar mean trip duration (13.2 h for COMUs and 10.5 h for TBMUs) and similar diurnal patterns of diving (frequent dives to various depths in the daytime and less frequent dives to shallow depths in the nighttime). During the daytime, the dive depths of COMUs had two peaks in shallow (18.1 m) and deep (74.2 m) depths, while those of TBMUs were 20.2 m and 59.7 m. COMUs showed more frequent wing strokes during the bottom phase of dives (1.90 s-1) than TBMUs (1.66 s-1). Fish occurred more frequently in the bill loads of COMUs (85 %) than those of TBMUs (56 %). The δ15N value of blood was significantly higher in COMUs (14.5 ‰) than in TBMUs (13.1 ‰). The relatively small wing area (0.053 m2) of COMUs compared to TBMUs (0.067 m2) may facilitate their increased agility while foraging and allow them to capture more mobile prey such as larger fishes that inhabit deeper depths. These differences in food resource use may lead to the differential responses of the two murre species to marine environmental changes in the Bering Sea.

  16. Health-related quality of life in asthma: a comparison between the St George's Respiratory Questionnaire and the Asthma Quality of Life Questionnaire.

    PubMed

    Sanjuás, Carlos; Alonso, Jordi; Prieto, Luis; Ferrer, Montse; Broquetas, Joan M; Antó, Josep M

    2002-12-01

    The aim of the study is to compare the performance of the Juniper Asthma Quality of Life Questionnaire (AQLQ) and the St George's Respiratory Questionnaire (SGRQ) in a sample of asthmatic patients, representative of a broad spectrum of asthma severity. We studied 116 patients with a mean age (SD) of 42.6 (18.3) year. Patients were assessed twice, at recruitment and after 2 months, to determine the reliability, validity and responsiveness of the AQLQ and the SGRQ. Both questionnaires showed good reliability coefficients (> or = 0.70) which reached the standards for comparison at individual level (> or = 0.90) in the case of activity, impacts and overall SGRQ scores as well as symptoms, activities and overall AQLQ scores. Both AQLQ and SGRQ were able to discriminate among groups of patients based on asthma severity and control and showed, except for the symptoms domain of the SGRQ, large (standardized response means >0.8) and significant changes in the group of patients that improved at follow-up. We conclude that the AQLQ and SGRQ have shown high reliability and validity and, with the exception of the SGRQ symptoms, a high level of responsiveness. In overall terms, not one of these instruments seems to behave better than the other. PMID:12482157

  17. The spatial variability of nitrogen and phosphorus concentration in a sand aquifer influenced by onsite sewage treatment and disposal systems: a case study on St. George Island, Florida.

    PubMed

    Corbet, D Reide; Dillon, Kevin; Burnett, William; Schaefer, Geoff

    2002-01-01

    Groundwater from a shallow freshwater lens on St. George Island, a barrier island located in the Panhandle of Florida, eventually discharges into Apalachicola Bay or the Gulf of Mexico. Nutrient concentrations in groundwaters were monitored downfield from three onsite sewage treatment and disposal systems (OSTDS) on the island. Estimates of natural groundwater nutrient concentrations were obtained from an adjacent uninhabited island. Silicate, which was significantly higher in the imported drinking water relative to the surficial aquifer on St. George Island (12.2+/-1.9 mg Si l(-1) and 2.9+/-0.2 mg Si l(-1), respectively), was used as a natural conservative tracer. Our observations showed that nitrogen concentrations were attenuated to a greater extent than that of phosphorus relative to the conservative tracer. At the current setback distance (23 m), both nitrogen and phosphate concentrations are still elevated above natural levels by as much as 2 and 7 times, respectively. Increasing the setback distance to 50 m and raising the drainfields 1 m above the ground surface could reduce nutrient levels to natural concentrations (1.1+/-0.1 mg N l(-1), 0.20+/-0.02 mg P l(-1)). PMID:11916049

  18. High-Precision 40Ar/39Ar Geochronology and Geology of St. George Island, Pribilof Islands, Alaska: Implications for Eruption Rates in the Bering Sea Basalt Province

    NASA Astrophysics Data System (ADS)

    Feeley, T. C.; Cosca, M. A.; Hamblock, J. M.; Underwood, S. J.

    2007-12-01

    New high-precision 40Ar/39Ar ages and geologic mapping establish an eruptive chronology for St. George Island, Pribilof Islands, Alaska. St. George is part of the Bering Sea basalt province (BSBP), a group of 15 late Cenozoic (mostly < 6 Ma) alkalic to tholeiitic basaltic volcanic fields widely distributed on islands in the Bering Sea, along the west coast of Alaska, and along the coast of northeast Russia. Twelve samples of washed, but otherwise untreated, whole-rock basalts from St. George were cut with a micro-wire saw into chips ~3 mm3 in size and irradiated for 40Ar/39Ar analysis. The chips were incrementally heated with a CO2 laser equipped with an integrator lens, and analyzed using a NU Instruments Noblesse mass spectrometer equipped with a Faraday cup and two ion counting electron multipliers. Detector intercalibration was done using automated air pipettes. A minimum of 20 heating steps were measured per sample, with the data often defining age plateaux. Isochron plots of the data yield ages ranging from 1.57 ± 0.04 to 2.89 ± 0.11 Ma, with trapped 40Ar/36Ar ratios ranging from 312 to 330. The stratigraphic positions of the dated rocks are known directly from field relations and there are no discrepancies between the 40Ar/39Ar ages and this sequence. Geochemical data combined with the age data indicate no progressive petrologic trends during evolution of the magmatic system, except for intermittent eruption of distinctive plagioclase-phyric basalts with low to moderate MgO contents (7 - 5 wt%) beginning at ~2.0 Ma. The new age data combined with volume estimates indicate an average subaerial eruption rate of ~107 m3km-2yr-1, which is adjusted for 3% sedimentary and ultramafic basement rocks beneath the volcanic pile, an average vesicularity of 5%, and an assumed surficial erosion value of 20%. This rate is identical to the estimate (110 m3km-2yr-1) by Mukasa et al. (JGR 112, 2007) for St. George Island. Both estimates, however, do not account for

  19. Active layer thermal monitoring at Fildes Peninsula, King George Island, Maritime Antarctica

    NASA Astrophysics Data System (ADS)

    Michel, Roberto; Schaefer, Carlos; Simas, Felipe; Pregesbauer, Michael; Bockheim, James

    2013-04-01

    International attention on the climate change phenomena has grown in the last decade, intense modelling of climate scenarios were carried out by scientific investigations searching the sources and trends of these changes. The cryosphere and its energy flux became the focus of many investigations, being recognised as a key element for the understanding of future trends. The active layer and permafrost are key components of the terrestrial cryosphere due to their role in energy flux regulation and high sensitivity to climate change (Kane et al., 2001; Smith and Brown, 2009). Compared with other regions of the globe, our understanding of Antarctic permafrost is poor, especially in relation to its thermal state and evolution, its physical properties, links to pedogenesis, hydrology, geomorphic dynamics and response to global change (Bockheim, 1995, Bockheim et al., 2008). The active layer monitoring site was installed in the summer of 2008, and consist of thermistors (accuracy ± 0.2 °C) arranged in a vertical array (Turbic Eutric Cryosol 600 m asl, 10.5 cm, 32.5 cm, 67.5 cm and 83.5 cm). King George Island experiences a cold moist maritime climate characterized by mean annual air temperatures of -2°C and mean summer air temperatures above 0°C for up to four months (Rakusa-Suszczewski et al., 1993, Wen et al., 1994). Ferron et al., (2004) found great variability when analysing data from 1947 to1995 and identified cycles of 5.3 years of colder conditions followed by 9.6 years of warmer conditions. All probes were connected to a Campbell Scientific CR 1000 data logger recording data at hourly intervals from March 1st 2008 until November 30th 2012. Meteorological data for Fildes was obtained from the near by stations. We calculated the thawing days, freezing days; thawing degree days and freezing degree days; all according to Guglielmin et al. (2008). The active lawyer thickness was calculated as the 0 °C depth by extrapolating the thermal gradient from the two

  20. Melting and Metasomatism in the Mantle Lithosphere beneath the Pribilof Islands: Petrology and ICP-MS Analyses of Spinel Peridotite Xenoliths from St. George Island, Bering Sea, Alaska

    NASA Astrophysics Data System (ADS)

    Feeley, T. C.; Ulianov, A.; Underwood, S. J.

    2006-12-01

    A suite of protogranular spinel lherzolite xenoliths from an alkali basalt lava flow on St. George Island, Alaska, have been analyzed by for their bulk compositions by XRF and ICP-MS and for mineral compositions by electron microprobe and laser ablation ICP-MS. Bulk compositions of the peridotites range from relatively fertile (15-19% modal diopside) to depleted (10-8% modal diopside) and are consistent with variable degrees of melt extraction (7-18%) from a primitive mantle source. No hydrous minerals (e.g., mica or amphibole) were observed in any of the studied xenoliths. However, all xenoliths show melt-reaction textures characterized by glass-bearing, sieved textured rims on clinopyroxene and spinel. In several samples, complete clinopyroxene grains show sieve texture and are associated with melt pockets composed of coexisting silicic glass (Na- ± K-rich) and quench-textured olivine, spinel, clinopyroxene, and feldspar. In general, clinopyroxene and whole-rock chondrite-normalized REE patterns are similar, indicating that the whole-rock compositions reliably record the pre-entrainment REE patterns of the xenoliths. Whole-rock and clinopyroxene REE patterns show a considerable range from LREE-depleted to LREE-enriched, with most samples having flat to MREE-enriched patterns. The REE systematics suggest that most St. George lherzolites experienced little metasomatic overprinting of highly incompatible trace elements following melt extraction. In this regard, only the most refractory sample studied shows clear compositional evidence for metasomatism, as reflected in high whole-rock and clinopyroxene LREE/HREE ratios and abundances of other highly incompatible trace elements (e.g., Th, Ta, Nb, Rb, Sr). Based on the pervasive homogenization of this metasomatic signature, it is likely that it does not reflect a recent event related to the magmatism that brought the xenoliths to the surface. In spite of this evidence, the melt-reaction textures clearly demonstrate

  1. Introductory Astronomy Student-Centered Active Learning at The George Washington University

    NASA Astrophysics Data System (ADS)

    Cobb, Bethany

    2014-01-01

    The Physics Department at the George Washington University has been successfully using student-centered active learning (SCALE-UP) in physics classes since 2008. In Fall 2011, we began implementing introductory (non-majors) astronomy classes taught in the student-centered active learning mode. Class time is devoted to engaging in hands-on activities and laboratories, and tackling thought-provoking questions and problems. Students work together in small groups to gain a deeper understanding of the material. Multiple instructors circulate to answer questions and engage students in additional contemplation of the material. Research has shown that students who are engaged in this manner have an increased conceptual understanding and are better able to solve problems. This talk will describe our methods, our successes and the associated challenges of integrating active learning into courses entitled “Stars, Planets and Life” and “Introduction to the Cosmos.”

  2. Probable relationships between the lower jurassic crocodilomorph trackways Batrachopus and Selenichus: Evidence and implications based on new finds from the St. George area southwestern Utah

    USGS Publications Warehouse

    Lockley, M.G.; Kirkland, J.; Milner, A.R.C.

    2003-01-01

    The enigmatic ichnogenus Selenichnus (Hitchcock, 1858) from the Lower Jurassic of Massachusetts and Utah may represent poorly preserved, extramorphollogical examples of Batrachopus. Selenichnus trackways from the St. George area (Utah) are virtually indistinguishable from the type material described by Hitchcock (1858) and Lull (1953) from Massachusetts. However, Selenichnus type specimens from Massachusetts, as well as the material from Utah, suggest a relationship with Batrachopus: The former track morphology appears to transform into the latter as preservational conditions change. The size and gait indicated by the two ichnogenera are similar. The suggested relationship between the two ichnogenera does not alter the fact that there are distinct differences in the morphology of the type specimens. Thus, pending discovery of more material, formal synonymy of the two ichnogenera is not formally proposed. ?? Taylor and Francis Inc.

  3. Mount St. Helens Classroom Activities: Secondary.

    ERIC Educational Resources Information Center

    Washington State Educational Service District 112, Vancouver.

    This teacher's guide is designed to provide secondary teachers with an assortment of classroom activities dealing with the Mt. St. Helens eruption of May 18, 1980, in the areas of science, social studies, math, language arts and school newspaper activities. Copy masters and teacher versions of all activities are contained within this guide,…

  4. Mount St. Helens Classroom Activities: Elementary.

    ERIC Educational Resources Information Center

    Washington State Educational Service District 112, Vancouver.

    This teacher's guide is designed to provide elementary teachers with an assortment of classroom activities dealing with the Mt. St. Helens eruption of May 18, 1980, in the areas of science, social studies, math, language arts, and school newspaper activities. Copy masters and teacher versions of all activities are contained with this guide,…

  5. Introductory Astronomy Student-Centered Active Learning at the George Washington University

    NASA Astrophysics Data System (ADS)

    Cobb, B. E.

    2014-07-01

    The Physics Department at the George Washington University has been successfully using student-centered active learning (SCALE-UP) in physics classes since 2008. Recently (since fall 2011), we have been developing and implementing introductory (non-majors) astronomy classes taught in the student-centered active learning mode. Class time is devoted to engaging in hands-on activities and laboratories and tackling questions and problems in a workbook. Students work in small groups, and multiple instructors circulate to answer questions and engage students in the material. Research has shown that students who are engaged in this manner have an increased conceptual understanding of the material. In developing our “Stars, Planets and Life” course into an interactive class, we encountered many challenges, but there have also been positive outcomes. Improvements to this class are ongoing, and in fall of 2013 we will begin full implementation of SCALE-UP in our “Introduction to the Cosmos” course.

  6. Active-layer thermal monitoring on the Fildes Peninsula, King George Island, maritime Antarctica

    NASA Astrophysics Data System (ADS)

    Michel, R. F. M.; Schaefer, C. E. G. R.; Simas, F. M. B.; Francelino, M. R.; Fernandes-Filho, E. I.; Lyra, G. B.; Bockheim, J. G.

    2014-12-01

    International attention to climate change phenomena has grown in the last decade; the active layer and permafrost are of great importance in understanding processes and future trends due to their role in energy flux regulation. The objective of this paper is to present active-layer temperature data for one Circumpolar Active Layer Monitoring South hemisphere (CALM-S) site located on the Fildes Peninsula, King George Island, maritime Antarctica over an 57-month period (2008-2012). The monitoring site was installed during the summer of 2008 and consists of thermistors (accuracy of ±0.2 °C), arranged vertically with probes at different depths, recording data at hourly intervals in a high-capacity data logger. A series of statistical analyses was performed to describe the soil temperature time series, including a linear fit in order to identify global trends, and a series of autoregressive integrated moving average (ARIMA) models was tested in order to define the best fit for the data. The affects of weather on the thermal regime of the active layer have been identified, providing insights into the influence of climate change on permafrost. The active-layer thermal regime in the studied period was typical of periglacial environments, with extreme variation in surface during the summer resulting in frequent freeze and thaw cycles. The active-layer thickness (ALT) over the studied period shows a degree of variability related to different annual weather conditions, reaching a maximum of 117.5 cm in 2009. The ARIMA model could describe the data adequately and is an important tool for more conclusive analysis and predictions when longer data sets are available. Despite the variability when comparing temperature readings and ACT over the studied period, no trend can be identified.

  7. Active layer thermal monitoring at Fildes Peninsula, King George Island, Maritime Antarctica

    NASA Astrophysics Data System (ADS)

    Michel, R. F. M.; Schaefer, C. E. G. R.; Simas, F. N. B.; Francelino M., R.; Fernandes-Filho, E. I.; Lyra, G. B.; Bockheim, J. G.

    2014-07-01

    International attention to the climate change phenomena has grown in the last decade; the active layer and permafrost are of great importance in understanding processes and future trends due to their role in energy flux regulation. The objective of the this paper is to present active layer temperature data for one CALM-S site located at Fildes Peninsula, King George Island, Maritime Antarctica over an fifth seven month period (2008-2012). The monitoring site was installed during the summer of 2008 and consists of thermistors (accuracy of ± 0.2 °C), arranged vertically with probes at different depths, recording data at hourly intervals in a~high capacity data logger. A series of statistical analysis were performed to describe the soil temperature time series, including a linear fit in order to identify global trend and a series of autoregressive integrated moving average (ARIMA) models were tested in order to define the best fit for the data. The controls of weather on the thermal regime of the active layer have been identified, providing insights about the influence of climate chance over the permafrost. The active layer thermal regime in the studied period was typical of periglacial environment, with extreme variation at the surface during summer resulting in frequent freeze and thaw cycles. The active layer thickness (ALT) over the studied period showed variability related to different annual weather conditions, reaching a maximum of 117.5 cm in 2009. The ARIMA model was considered appropriate to treat the dataset, enabling more conclusive analysis and predictions when longer data sets are available. Despite the variability when comparing temperature readings and active layer thickness over the studied period, no warming trend was detected.

  8. George Bank

    NASA Astrophysics Data System (ADS)

    Codispoti, L. A.

    This book provides a rich feast for anyone who has a hunger to learn more about Georges Bank! Its 593 large pages provide articles on a wide variety of scientific and resource management topics. Many human interest features are also included. Among the latter are a photograph demonstrating the only proper way for a seagoing chemist to imbibe, and articles entitled, “My First Trip on Georges Bank,” and “‘Bait Up!’: Dory Fishing on Georges Bank.”Proving that every cloud has a silver lining, interest in producing this book was driven by the climate of controversy that surrounded Georges Bank in the latter 1970s and early 1980s. This was a time when exploratory wells were being driven to search for oil and when disputes between Canada and the United States about jurisdiction over the Bank were reaching their peak. As Backus notes in the Foreword, Woods Hole Oceanographic Institution, Woods Hole, Mass., set up a Coastal Research Center in 1979 when “the oil/fish dispute on Georges Bank was hot.” The direct costs of publishing this book were, in turn, supported by the Coastal Research Center.

  9. Active layer thermal regime at different vegetation covers at Lions Rump, King George Island, Maritime Antarctica

    NASA Astrophysics Data System (ADS)

    Almeida, Ivan C. C.; Schaefer, Carlos Ernesto G. R.; Fernandes, Raphael B. A.; Pereira, Thiago T. C.; Nieuwendam, Alexandre; Pereira, Antônio Batista

    2014-11-01

    Climate change impacts the biotic and abiotic components of polar ecosystems, affecting the stability of permafrost, active layer thickness, vegetation, and soil. This paper describes the active layer thermal regimes of two adjacent shallow boreholes, under the same soil but with two different vegetations. The study is location in Lions Rump, at King George Island, Maritime Antarctic, one of the most sensitive regions to climate change, located near the climatic limit of Antarctic permafrost. Both sites are a Turbic Cambic Cryosol formed on andesitic basalt, one under moss vegetation (Andreaea gainii, at 85 m a.s.l.) and another under lichen (Usnea sp., at 86 m a.s.l.), located 10 m apart. Ground temperature at same depths (10, 30 and 80 cm), water content at 80 cm depth and air temperature were recorded hourly between March 2009 and February 2011. The two sites showed significant differences in mean annual ground temperature for all depths. The lichen site showed a higher soil temperature amplitude compared to the moss site, with ground surface (10 cm) showing the highest daily temperature in January 2011 (7.3 °C) and the lowest daily temperature in August (- 16.5 °C). The soil temperature at the lichen site closely followed the air temperature trend. The moss site showed a higher water content at the bottommost layer, consistent with the water-saturated, low landscape position. The observed thermal buffering effect under mosses is primarily associated with higher moisture onsite, but a longer duration of the snowpack (not monitored) may also have influenced the results. Active layer thickness was approximately 150 cm at low-lying moss site, and 120 cm at well-drained lichen site. This allows to classify these soils as Cryosols (WRB) or Gelisols (Soil Taxonomy), with evident turbic features.

  10. Geophysical fingerprints of shallow cultural structures from microgravity and GPR measurements in the Church of St. George, Svätý Jur, Slovakia

    NASA Astrophysics Data System (ADS)

    Panisova, Jaroslava; Murín, Igor; Pašteka, Roman; Haličková, Jana; Brunčák, Peter; Pohánka, Vladimír; Papčo, Juraj; Milo, Peter

    2016-04-01

    Recording of the historic edifice using the state-of-the-art geodetic and geophysical techniques brings easier visualisation in form of a three-dimensional (3D) model, thus allowing better understanding of its historical construction by the public and non-experts. We have applied this approach at the Church of St. George, one of the most significant religious buildings in south-western Slovakia, which dominates a silhouette of the town Svätý Jur. The geodetic survey allowed to record the actual state of the church. The church exterior was surveyed using a total station. Due to the intricate shape of the interior components of the church, it was decided to use a terrestrial laser scanner to generate the point cloud data, which were processed into floor plan, elevations, sectional 2D drawings and 3D model. The geophysical survey was carried out in the interior of the church in order to identify potential subsurface anthropogenic structures. Microgravity and ground penetrating radar (GPR) methods were selected as the most effective geophysical tools for such task. In microgravity data processing we focused on the calculation and removal of the gravitational effects of the building masses. The main negative gravity anomalies of interest in the nave, which also have been confirmed by GPR measurements, are interpreted as medieval crypts. Another very important outcome of the geophysical survey is the discovery of the west wall foundations of the oldest Romanesque construction. From each geophysical data acquired we derived 3D polygonal models, which are compared to achieve more realistic picture of the subsurface structures. Verification of these structures by means of archaeological excavation has not been carried out yet.

  11. Mount St. Helens' volcanic ash: hemolytic activity.

    PubMed

    Vallyathan, V; Mentnech, M S; Stettler, L E; Dollberg, D D; Green, F H

    1983-04-01

    Volcanic ash samples from four Mount St. Helens' volcanic eruptions were subjected to mineralogical, analytical, and hemolytic studies in order to evaluate their potential for cytotoxicity and fibrogenicity. Plagioclase minerals constituted the major component of the ash with free crystalline silica concentrations ranging from 1.5 to 7.2%. The in vitro hemolytic activity of the volcanic ash was compared to similar concentrations of cytotoxic and inert minerals. The ash was markedly hemolytic, exhibiting an activity similar to chrysotile asbestos, a known fibrogenic agent. The hemolysis of the different ash samples varied with particle size but not with crystalline silica concentration. The results of these studies taken in conjunction with the results of our animal studies indicate a fibrogenic potential of volcanic ash in heavily exposed humans. PMID:6832120

  12. Foraging segregation of two congeneric diving seabird species (common and thick-billed murres) breeding on St. George Island, Bering Sea

    NASA Astrophysics Data System (ADS)

    Kokubun, N.; Yamamoto, T.,; Sato, N.; Watanuki, Y.; Will, A.; Kitaysky, A. S.; Takahashi, A.

    2015-11-01

    Sub-arctic environmental changes are expected to affect the ecology of marine top predators. We examined the characteristics of foraging behavior of two sympatric congeneric diving seabirds, common (Uria aalge: hereafter COMU) and thick-billed (U. lomvia: hereafter TBMU) murres breeding on St. George Island located in the seasonal sea-ice region of the Bering Sea. We investigated their flight duration, diel patterns of dive depth, and underwater wing strokes, along with morphology and blood stable isotopes. Acceleration-temperature-depth data loggers were attached to chick-guarding birds, and behavioral data were obtained from 7 COMU and 12 TBMU. Both species showed similar trip duration (13.21 ± 4.79 h for COMU and 10.45 ± 7.09 h for TBMU) and similar diurnal patterns of diving (frequent dives to various depths in the daytime and less frequent dives to shallow depths in the nighttime). During the daytime, dive depths of COMU had two peaks in shallow (18.1 ± 6.0 m) and deep (74.2 ± 8.7 m) depths, while those of TBMU were 20.2 ± 7.4 m and 59.7 ± 7.9 m. COMU showed more frequent wing strokes during the bottom phase of dives (1.90 ± 0.11 s-1) than TBMU (1.66 ± 0.15 s-1). Fishes occurred with higher proportion in the bill-loads brought back to chicks in COMU (85 %) than in TBMU (56 %). δ15N value of blood was significantly higher in COMU (14.47 ± 0.27 ‰) than in TBMU (13.14 ± 0.36 ‰). Relatively small wing area (0.053 ± 0.007 m2) of COMU compared to TBMU (0.067 ± 0.007 m2) may make them more agile underwater and thus enable them to target more mobile prey including larger fishes that inhabit deeper depths. These differences in foraging behavior between COMU and TBMU might explain the differences in their responses to long-term marine environmental changes.

  13. 75 FR 80471 - Takes of Marine Mammals Incidental to Specified Activities; St. George Reef Light Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-22

    ... National Oceanic and Atmospheric Administration RIN 0648-XZ87 Takes of Marine Mammals Incidental to... Norte County, CA AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric... frequently used in the discussions of acoustic effects in this document. Sound pressure is the sound...

  14. George Wald memorial talk.

    PubMed

    Hubbard, R; Wald, E

    1999-01-01

    George Wald was born in 1906 in New York City to immigrant parents. An early and voracious reader, he soon developed a wide range of interests and entered New York University as a pre-law student, the first in his family to attend college. Shortly shifting to pre-medicine, he graduated college in biology. For graduate work, he joined the laboratory of Selig Hecht, a pioneer in vision research, at Columbia University. In 1932, four months before Hitler came to power, George went to Berlin to do postdoctoral work in the laboratory of Otto Warburg and there found vitamin A in the retina. This launched his life-long explorations of the molecular basis of vision for which he received the Nobel Prize in Physiology or Medicine in 1967. During the 1960s, George became increasingly involved in anti-war and anti-nuclear activities, writing and travelling widely, including multiple trips to commemorations of the bombings of Hiroshima and Nagasaki sponsored by Japanese colleagues. He considered these activities part of being a biologist, someone concerned with life. In his final years, he turned to questions about consciousness, writing and speaking about 'Life and Mind in the Universe'. PMID:10614043

  15. Deep-water hydrocarbon potential of Georges Bank Trough

    SciTech Connect

    Levie, D.S. Jr.

    1985-02-01

    Characterization of the petroleum potential for Georges Bank Trough has been based primarily on limited organic geochemical data that indicate the area of recent drilling activity behind the paleoshelf edge to be poor in organic carbon and C/sub 15/ + extract values, with predominantly terrestrial kerogen types. Maturation data also suggest an inadequate thermal history for hydrocarbon generation in the area. It is possible that the effects of heat flow from the New England Seamount Chain may contribute to hydrocarbon generation in the Georges Bank Trough - a relationship that may also exist between the Newfoundland Seamount Chain and the Hibernia area of the Grand Banks. Also, comparisons can be drawn between the Atlantic Fracture Zone bordering the Georges Bank Trough and the Romanche-St. Paul Fracture Zone off the Ivory Coast. In the latter region, restricted anoxic environments with sediments rich in marine kerogen types have been identified, as have both structural and stratigraphic trapping mechanisms. Within this rhombochasm configuration, reservoir lithologies of sandstone and carbonate turbidites, fractured deep-water chalks, and reefal limestones should occur. The relationships of seamount to fracture zone, as applied to the rhombochasm model for the Georges Bank Trough, should enhance the hydrocarbon potential of the lower Mesozoic sediments seaward of the paleoshelf edge and thus classify this area as a future major hydrocarbon province.

  16. Diversity and extracellular enzymatic activities of yeasts isolated from King George Island, the sub-Antarctic region

    PubMed Central

    2012-01-01

    Background Antarctica has been successfully colonized by microorganisms despite presenting adverse conditions for life such as low temperatures, high solar radiation, low nutrient availability and dryness. Although these “cold-loving” microorganisms are recognized as primarily responsible for nutrient and organic matter recycling/mineralization, the yeasts, in particular, remain poorly characterized and understood. The aim of this work was to study the yeast microbiota in soil and water samples collected on King George Island. Results A high number of yeast isolates was obtained from 34 soil and 14 water samples. Molecular analyses based on rDNA sequences revealed 22 yeast species belonging to 12 genera, with Mrakia and Cryptococcus genera containing the highest species diversity. The species Sporidiobolus salmonicolor was by far the most ubiquitous, being identified in 24 isolates from 13 different samples. Most of the yeasts were psychrotolerant and ranged widely in their ability to assimilate carbon sources (consuming from 1 to 27 of the 29 carbon sources tested). All species displayed at least 1 of the 8 extracellular enzyme activities tested. Lipase, amylase and esterase activity dominated, while chitinase and xylanase were less common. Two yeasts identified as Leuconeurospora sp. and Dioszegia fristingensis displayed 6 enzyme activities. Conclusions A high diversity of yeasts was isolated in this work including undescribed species and species not previously isolated from the Antarctic region, including Wickerhamomyces anomalus, which has not been isolated from cold regions in general. The diversity of extracellular enzyme activities, and hence the variety of compounds that the yeasts may degrade or transform, suggests an important nutrient recycling role of microorganisms in this region. These yeasts are of potential use in industrial applications requiring high enzyme activities at low temperatures. PMID:23131126

  17. The role of mitochondrial fusion and StAR phosphorylation in the regulation of StAR activity and steroidogenesis.

    PubMed

    Castillo, Ana F; Orlando, Ulises; Helfenberger, Katia E; Poderoso, Cecilia; Podesta, Ernesto J

    2015-06-15

    The steroidogenic acute regulatory (StAR) protein regulates the rate-limiting step in steroidogenesis, i.e. the delivery of cholesterol from the outer (OMM) to the inner (IMM) mitochondrial membrane. StAR is a 37-kDa protein with an N-terminal mitochondrial targeting sequence that is cleaved off during mitochondrial import to yield 30-kDa intramitochondrial StAR. StAR acts exclusively on the OMM and its activity is proportional to how long it remains on the OMM. However, the precise fashion and the molecular mechanism in which StAR remains on the OMM have not been elucidated yet. In this work we will discuss the role of mitochondrial fusion and StAR phosphorylation by the extracellular signal-regulated kinases 1/2 (ERK1/2) as part of the mechanism that regulates StAR retention on the OMM and activity. PMID:25540920

  18. Famous Americans: George Washington & Abraham Lincoln.

    ERIC Educational Resources Information Center

    Fleming, Maria

    Introducing students in grade 1-3 to George Washington and Abraham Lincoln, this book presents thematic units that present biographical information, and literature links such as poems, songs, stories, cross-curricular activities, and hands-on reproducibles. Chapters in the book are: (1) Getting to Know George; (2) The Father and His Country; (3)…

  19. 6. Photocopy of photograph (from the collection of Prof. George ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photocopy of photograph (from the collection of Prof. George H. Bishop) Photographer unknown ca. 1927 NORTH REAR, FROM THE NORTHWEST - William Long Log House, 9385 Pardee Road, Crestwood, St. Louis County, MO

  20. 5. Photocopy of photograph (from the collection of Prof. George ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photocopy of photograph (from the collection of Prof. George H. Bishop) Photographer unknown ca. 1927 NORTH REAR AND EAST SIDE - William Long Log House, 9385 Pardee Road, Crestwood, St. Louis County, MO

  1. 4. Photocopy of photograph (from the collection of Prof. George ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photocopy of photograph (from the collection of Prof. George H. Bishop) Photographer unknown ca. 1927 SOUTH FRONT AND WEST SIDE - William Long Log House, 9385 Pardee Road, Crestwood, St. Louis County, MO

  2. 3. Photocopy of photograph (from the collection of Prof. George ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photocopy of photograph (from the collection of Prof. George H. Bishop) Photographer unknown early 20th century SOUTH FRONT AND WEST SIDE, FROM ACROSS FIELDS - William Long Log House, 9385 Pardee Road, Crestwood, St. Louis County, MO

  3. 4. Historic American Buildings Survey George Harkness III, Photographer, April ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey George Harkness III, Photographer, April 10, 1934 VIEW OF DOME AND LANTERN FROM NORTH - Old St. Louis Courthouse, Fourth to Broadway, Market to Chestnut Streets, Saint Louis, Independent City, MO

  4. 3. Historic American Buildings Survey George Harkness III, Photographer, April ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey George Harkness III, Photographer, April 10, 1934 VIEW OF DOME AND DRUM FROM NORTH - Old St. Louis Courthouse, Fourth to Broadway, Market to Chestnut Streets, Saint Louis, Independent City, MO

  5. Model Eliciting Activities: Fostering 21st Century Learners

    ERIC Educational Resources Information Center

    Stohlmann, Micah

    2013-01-01

    Real world mathematical modeling activities can develop needed and valuable 21st century skills. The knowledge and skills to become adept at mathematical modeling need to develop over time and students in the elementary grades should have experiences with mathematical modeling. For this to occur elementary teachers need to have positive…

  6. General George C. Marshall

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This is a portrait of General George C. Marshall in Army uniform. The Marshall Space Flight Center, a NASA field installation, was established in Huntsville, Alabama, in 1960. The Center was named in honor of General George C. Marshall, the Army Chief of Staff during World War II, Secretary of State, and Nobel Prize Wirner for his world-renowned Marshall Plan.

  7. Radiotherapy Breast Boost With Reduced Whole-Breast Dose Is Associated With Improved Cosmesis: The Results of a Comprehensive Assessment From the St. George and Wollongong Randomized Breast Boost Trial

    SciTech Connect

    Hau, Eric; Browne, Lois H.; Khanna, Sam; Cail, Stacy; Cert, Grad; Chin, Yaw; Clark, Catherine; Inder, Stephanie; Szwajcer, Alison; Graham, Peter H.

    2012-02-01

    Purpose: To evaluate comprehensively the effect of a radiotherapy boost on breast cosmetic outcomes after 5 years in patients treated with breast-conserving surgery. Methods: The St. George and Wollongong trial (NCT00138814) randomized 688 patients with histologically proven Tis-2, N 0-1, M0 carcinoma to the control arm of 50 Gy in 25 fractions (342 patients) and the boost arm of 45 Gy in 25 fractions to the whole breast followed by a 16 Gy in 8 fraction electron boost (346 patients). Five-year cosmetic outcomes were assessed by a panel subjectively in 385 patients and objectively using pBRA (relative breast retraction assessment). A subset of patients also had absolute BRA measurements. Clinician assessment and patient self-assessment of overall cosmetic and specific items as well as computer BCCT.core analysis were also performed. Results: The boost arm had improved cosmetic overall outcomes as scored by the panel and BCCT.core software with 79% (p = 0.016) and 81% (p = 0.004) excellent/good cosmesis respectively compared with 68% in no-boost arm. The boost arm also had lower pBRA and BRA values with a mean difference of 0.60 and 1.82 mm, respectively, but was not statistically significant. There was a very high proportion of overall excellent/good cosmetic outcome in 95% and 93% in the boost and no-boost arms using patient self-assessment. However, no difference in overall and specific items scored by clinician assessment and patient self-assessment was found. Conclusion: The results show the negative cosmetic effect of a 16-Gy boost is offset by a lower whole-breast dose of 45 Gy.

  8. ITOW: George Hoggard

    NASA Video Gallery

    George Hoggard served on the Flight Crew Rescue unit for the fire department at NASA's Kennedy Space Center from 1968 to 2011. He helped train Apollo and space shuttle astronauts for emergency situ...

  9. George: Gaussian Process regression

    NASA Astrophysics Data System (ADS)

    Foreman-Mackey, Daniel

    2015-11-01

    George is a fast and flexible library, implemented in C++ with Python bindings, for Gaussian Process regression useful for accounting for correlated noise in astronomical datasets, including those for transiting exoplanet discovery and characterization and stellar population modeling.

  10. Obituary: George W. Wetherill (1925-2006)

    NASA Astrophysics Data System (ADS)

    Weissman, Paul

    2006-10-01

    George West Wetherill, a pioneer of geochronolgy and planetary science, passed away from heart failure at his home in Washington, D.C., on 19 July 2006, one month short of his 81st birthday. Wetherill, director emeritus of the Carnegie Institution of Washington's Department of Terrestrial Magnetism, made major contributions to a wide variety of fields, including geochronology and the formation of the planets.

  11. Superstitions of George Bartisch.

    PubMed

    Blanchard, Donald L

    2005-01-01

    George Bartisch was a 16th century German ophthalmologist who published the first ophthalmology textbook in the vernacular for laymen and non-university-trained practitioners. His treatments and understanding of diseases rested firmly on Greek tradition, but he also was very involved in the superstitions of the day. This essay looks at the man and his mores. Bartisch believed that much of the suffering of patients had to do with sins they had committed, and that the devil was the active force in the world inflicting this punishment. Often, he believed, witches would carry out the devil's hexes, in the form of either hot or cold witchcraft. Bartisch also felt that astrology played a major role in the outcome of surgery. Because of that he practiced only during certain astrological signs, and in the proper waxing and waning phases of the moon. He also linked many common problems to sins. For example, presbyopia was presented as due to excessive use of alcohol. Glasses were to be avoided because he felt they destroyed vision in themselves. Despite these superstitions and misconceptions, Bartisch was an honorable professional and his books give insight into the making of a good ophthalmologist. PMID:16139042

  12. Electrical activity during the 2006 Mount St. Augustine volcanic eruptions

    USGS Publications Warehouse

    Thomas, Ronald J.; Krehbiel, Paul R.; Rison, William; Edens, H. E.; Aulich, G. D.; McNutt, S.R.; Tytgat, Guy; Clark, E.

    2007-01-01

    By using a combination of radio frequency time-of-arrival and interferometer measurements, we observed a sequence of lightning and electrical activity during one of Mount St. Augustine's eruptions. The observations indicate that the electrical activity had two modes or phases. First, there was an explosive phase in which the ejecta from the explosion appeared to be highly charged upon exiting the volcano, resulting in numerous apparently disorganized discharges and some simple lightning. The net charge exiting the volcano appears to have been positive. The second phase, which followed the most energetic explosion, produced conventional-type discharges that occurred within plume. Although the plume cloud was undoubtedly charged as a result of the explosion itself, the fact that the lightning onset was delayed and continued after and well downwind of the eruption indicates that in situ charging of some kind was occurring, presumably similar in some respects to that which occurs in normal thunderstorms.

  13. Electrical activity during the 2006 Mount St. Augustine volcanic eruptions.

    PubMed

    Thomas, R J; Krehbiel, P R; Rison, W; Edens, H E; Aulich, G D; Winn, W P; McNutt, S R; Tytgat, G; Clark, E

    2007-02-23

    By using a combination of radio frequency time-of-arrival and interferometer measurements, we observed a sequence of lightning and electrical activity during one of Mount St. Augustine's eruptions. The observations indicate that the electrical activity had two modes or phases. First, there was an explosive phase in which the ejecta from the explosion appeared to be highly charged upon exiting the volcano, resulting in numerous apparently disorganized discharges and some simple lightning. The net charge exiting the volcano appears to have been positive. The second phase, which followed the most energetic explosion, produced conventional-type discharges that occurred within plume. Although the plume cloud was undoubtedly charged as a result of the explosion itself, the fact that the lightning onset was delayed and continued after and well downwind of the eruption indicates that in situ charging of some kind was occurring, presumably similar in some respects to that which occurs in normal thunderstorms. PMID:17322054

  14. Unveiling the Broze Bust of General George C. Marshall

    NASA Technical Reports Server (NTRS)

    1960-01-01

    President Eisenhower and Mrs. Marshall unveil the bronze bust of General George C. Marshall at the dedication ceremony of the NASA George C. Marshall Space Flight Center on September 8. 1960. On March 15, 1960, a Presidential Executive Order arnouced that the missile development complex within the boundaries of Redstone Arsenal would become the George C. Marshall Space Flight Center (MSFC). The Center was activated on July 1, 1960

  15. Potato StCONSTANS-like1 Suppresses Storage Organ Formation by Directly Activating the FT-like StSP5G Repressor.

    PubMed

    Abelenda, José A; Cruz-Oró, Eduard; Franco-Zorrilla, José Manuel; Prat, Salomé

    2016-04-01

    The CONSTANS-FT pathway defines a core module for reproductive transition in both long-day (LD) and short-day (SD) plants. Changes in the transcriptional function of the CONSTANS (CO) protein have been proposed to mediate differential SD activation of FLOWERING LOCUS T (FT) orthologs in SD plants. Potato Andigena genotypes have an obligate SD requirement for tuber formation, and this photoperiodic response correlates with activation of the FT StSP6A gene in leaves. The potato StCOL1 factor represses expression of this mobile tuberization signal, but the control mechanism is poorly understood. Here, we analyzed StCOL1 diurnal oscillation and protein accumulation at different photoperiods and light wavelengths. We observed that the potato StCOL1 gene peaked at dawn and that, in contrast to the Arabidopsis AtCO homolog, the light receptor phyB is necessary for protein stabilization in the light. Reduced StCOL1 levels in RNAi lines strongly correlated with downregulated expression of an additional potato FT family member, StSP5G. Co-regulated StCOL1 and StSP5G expression suggested that StCOL1 activates this target directly rather than controlling StSP6A expression. By hybridization of a universal protein-binding microarray, we established that StCOL1 binds a TGTGGT element, and we found that immunoprecipitated StCOL1 protein fractions were enriched in StSP5G promoter fragments bearing this element. We show that StSP5G represses tuberization in LD conditions and that this FT-like homolog suppresses StSP6A gene expression. Rewiring StCOL1 transcriptional function from direct activation of the StSP6A inducer signal to the control of an FT-like repressor thus mediates the strict SD requirement of Andigena plants for tuberization. PMID:26972319

  16. Baker & Taylor's George Coe

    ERIC Educational Resources Information Center

    Fialkoff, Francine

    2009-01-01

    In his 30 years as a library wholesaler, first as VP and general manager of Brodart Books, Library, and School Automation divisions and since 2000 as president of the Library & Education division of Baker & Taylor (B&T), George Coe has been instrumental in a whole host of innovations. They go way beyond the selection, processing, and delivery of…

  17. Who Framed George Lakoff?

    ERIC Educational Resources Information Center

    Goldstein, Evan R.

    2008-01-01

    In this article, a noted linguist reflects on his tumultuous foray into politics. For years George P. Lakoff has been at the center of some of the biggest intellectual disagreements in linguistics (most famously with Noam Chomsky) and has helped create an important interdisciplinary field of study, cognitive linguistics, that is reshaping people's…

  18. Ten Tips from George.

    ERIC Educational Resources Information Center

    Lee, Helen C.

    The paper describes a current events lesson based on an editorial which quoted 10 tips from George Washington and suggested that a review of Washington's statements might be useful in making judgments about current national issues. Used in United States history, world history, and government classes, adaptation and revision of the tips lead…

  19. Connecting to Curious George

    ERIC Educational Resources Information Center

    Hinshaw, Craig

    2006-01-01

    Each month throughout the school year, two second grade teachers at Lessenger Elementary highlight a different children's author. The interdisciplinary lessons that evolved the month they selected Margaret and H.A. Rey's Curious George books were the most successful. In this article, the author relates how art, story writing, reading aloud, and…

  20. General George C. Marshall

    NASA Technical Reports Server (NTRS)

    2004-01-01

    The Marshall Space Flight Center, a NASA field installation, was established at Huntsville, Alabama, in 1960. The Center was named in honor of General George C. Marshall, the Army Chief of Staff during World War II, Secretary of State, and Nobel Prize Wirner for his world-renowned Marshall Plan.

  1. 78 FR 19632 - Special Local Regulations; St. Thomas Carnival Watersport Activities, Charlotte Amalie Harbor; St...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-02

    ... DHS Department of Homeland Security FR Federal Register NPRM Notice of Proposed Rulemaking A. Public... Act notice regarding our public dockets in the January 17, 2008, issue of the Federal Register (73 FR... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulations; St. Thomas...

  2. 33 CFR 334.761 - Naval Support Activity Panama City; St. Andrews Bay; restricted areas.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... City; St. Andrews Bay; restricted areas. 334.761 Section 334.761 Navigation and Navigable Waters CORPS... REGULATIONS § 334.761 Naval Support Activity Panama City; St. Andrews Bay; restricted areas. (a) The areas—(1... in this section shall be enforced by the Commanding Officer, Naval Support Activity, Panama...

  3. Georges Bank conflict resolved

    NASA Astrophysics Data System (ADS)

    Robb, David W.

    1984-04-01

    The International Court of Justice has resolved the long-term conflict between the United States and Canada over claims to mineral and living resources lying along the countries' common Atlantic maritime border. On October 12, in a 4-1 decision, the World Court rejected the United States' claim to the entire Georges Bank area, a region of the Continental Shelf off Massachusetts and Nova Scotia that is a prime fishing ground and is believed to have good potential for oil and gas deposits as well. The disputed area is roughly the top third of the Georges Bank area. The court awarded each country approximately half of this disputed area. No appeals are allowed under this decision.

  4. 2. Photocopy of original photograph in collection of George S. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photocopy of original photograph in collection of George S. DeMenil, St. Louis. Photographer unknown. Photograph taken before house was dismantled in the 1930s. Furniture originally from home of A.P. Chouteau. VIEW OF PARLOR, SHOWING FIREPLACE MANTELS - Nicholas DeMenil House, Thirteenth & Cherokee Streets, Saint Louis, Independent City, MO

  5. 3. Photocopy of original photograph in collection of George S. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photocopy of original photograph in collection of George S. DeMenil, St. Louis. Photographer unknown. Photograph taken before house was dismantled in the 1930s. Furniture originally from home of A.P. Chouteau. VIEW OF PARLOR, SHOWING OVAL MIRROR - Nicholas DeMenil House, Thirteenth & Cherokee Streets, Saint Louis, Independent City, MO

  6. 13. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 'TOW PATH ROW' HOUSES, AT EDGE OF CANAL BETWEEN THOMAS JEFFERSON AND 31st STREETS - Chesapeake & Ohio Canal, Georgetown Section, East & West parallel to M Street Northwest, Washington, District of Columbia, DC

  7. Famous Americans: George Washington and Abraham Lincoln.

    ERIC Educational Resources Information Center

    Fleming, Maria

    This book provides background information and ideas for teaching about George Washington and Abraham Lincoln at the primary grade level. Cross-curricular activities include work in music, writing, art, research, plays, and games. A pull-out poster with a poem on "President's Day" is stapled in the center of the book. Chapters in the book are: (1)…

  8. The George Rogers Clark Teaching Units.

    ERIC Educational Resources Information Center

    Indiana State Dept. of Natural Resources, Indianapolis.

    The curriculum guide provides elementary and secondary students and teachers with some specific suggestions for studying the events taking place in Kentucky and in Illinois during the American Revolution. Although George Rogers Clark is the central figure, the study is not limited to his story. His activities provide a framework for investigating…

  9. George Gamow's unique style

    NASA Astrophysics Data System (ADS)

    Pustylnik, I.

    We discuss some of the rich scientific legacy of George Gamov, an outstanding figure in physics and cosmology of the XXth century, whose talent has bridged the gap between East and West long before the decline of totalitarian system. Our analysis is based partly on Gamow's original scientific and popular papers, partly on the reminiscences of his colleagues and contemporaries (among other, R. A. Alpher, S. M. Ulam, A. A. Penzias, M. Delbruck). We discuss how these different facets of Gamow's rare talent are reflected in his transparent physical models and confront some of his predictions with the realities of contemporary extragalactic and observational cosmology.

  10. Non-typhoidal Salmonella Typhimurium ST313 isolates that cause bacteremia in humans stimulate less inflammasome activation than ST19 isolates associated with gastroenteritis

    PubMed Central

    Carden, Sarah; Okoro, Chinyere; Dougan, Gordon; Monack, Denise

    2014-01-01

    Salmonella is an enteric pathogen that causes a range of diseases in humans. Non-typhoidal Salmonella (NTS) serovars such as Salmonella enterica serovar Typhimurium generally cause a self-limiting gastroenteritis whereas typhoidal serovars cause a systemic disease, typhoid fever. However, S. Typhimurium isolates within the multi-locus sequence type ST313 have emerged in sub-Saharan Africa as a major cause of bacteremia in humans. The S. Typhimurium ST313 lineage is phylogenetically distinct from classical S. Typhimurium lineages, such as ST19, that cause zoonotic gastroenteritis worldwide. Previous studies have shown that the ST313 lineage has undergone genome degradation when compared to the ST19 lineage, similar to that observed for typhoidal serovars. Currently, little is known about phenotypic differences between ST313 isolates and other NTS isolates. We find that representative ST313 isolates invade non-phagocytic cells less efficiently than the classical ST19 isolates that are more commonly associated with gastroenteritis. In addition, ST313 isolates induce less Caspase-1-dependent macrophage death and IL-1β release than ST19 isolates. ST313 isolates also express relatively lower levels of mRNA of the genes encoding the SPI-1 effector sopE2 and the flagellin, fliC, providing possible explanations for the decrease in invasion and inflammasome activation. The ST313 isolates have invasion and inflammatory phenotypes that are intermediate; more invasive and inflammatory than Salmonella enterica serovar Typhi and less than ST19 isolates associated with gastroenteritis. This suggests that both phenotypically and at the genomic level ST313 isolates are evolving signatures that facilitate a systemic lifestyle in humans. PMID:25808600

  11. CARBON AND NITROGEN ACCUMULATION AND MICROBIAL ACTIVITY IN MOUNT ST. HELENS PYROCLASTIC SUBSTRATES AFTER 25 YEARS

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Lupines are important ecosystem engineers, linking above and belowground recovery of Mount St. Helens pyroclastic substrates by increasing soil organic matter and microbial activity and by influencing other biotic processes. Various soil properties were measured in samples collected from locations ...

  12. Geochemical precursors to volcanic activity at Mount St. Helens, USA.

    PubMed

    Berlo, Kim; Blundy, Jon; Turner, Simon; Cashman, Kathy; Hawkesworth, Chris; Black, Stuart

    2004-11-12

    The importance of the interplay between degassing and crystallization before and after the eruption of Mount St. Helens (Washington, USA) in 1980 is well established. Here, we show that degassing occurred over a period of decades to days before eruptions and that the manner of degassing, as deduced from geochemical signatures within the magma, was characteristic of the eruptive style. Trace element (lithium) and short-lived radioactive isotope (lead-210 and radium-226) data show that ascending magma stalled within the conduit, leading to the accumulation of volatiles and the formation of lead-210 excesses, which signals the presence of degassing magma at depth. PMID:15486253

  13. Pragmatism, Activism, and the Icy Slopes of Logic in George Reisch's Portrait of the Philosophy of Science as a Young Field

    ERIC Educational Resources Information Center

    Stump, David J.

    2009-01-01

    This paper considers several models of politically engaged philosophy with the aim of provoking discussion of George Reisch's "How the Cold War Transformed Philosophy of Science." At issue is the Unity of Science movement's conception of the philosophy of science in particular and what politically engaged philosophy of science might look like in…

  14. Serum ST2 in inflammatory bowel disease: a potential biomarker for disease activity.

    PubMed

    Boga, Salih; Alkim, Huseyin; Koksal, Ali Riza; Ozagari, Ayse Aysim; Bayram, Mehmet; Tekin Neijmann, Sebnem; Sen, Ilker; Alkim, Canan

    2016-06-01

    ST2, a specific ligand of interleukin 33, was described as a biomarker protein of inflammatory processes and overexpression of ST2 in ulcerative colitis (UC) was shown previously. We aimed to investigate the potential relationship of serum ST2 levels with the clinical, endoscopic and histopathological activity scores in UC and Crohn's disease (CD). Serum ST2 levels were determined in 143 patients with inflammatory bowel disease (IBD) (83 UC and 60 CD), in 50 healthy controls (HC), and in 32 patients with irritable bowel syndrome (IBS). Serum ST2 levels were elevated in IBD (56.8 (41.9-87.2) pg/mL) compared to HC and IBS (30.7 (20.2-54.3), p<0.001 and 39.9 (25.9-68.7) pg/mL, p=0.002, respectively). No significant difference was found between UC (54.2 (41.3-93.0) pg/mL) and CD (63.8 (42.7-88.4) pg/mL) and between IBS and HC. Serum ST2 levels were significantly increased in active UC compared to inactive UC (72.5 (44.1-99.5) vs 40.0 (34.7-51.6) pg/mL, p<0.001) and in active CD in comparison with inactive CD (63.8 (42.7-88.4) vs 48.4 (29.6-56.9) pg/mL, p=0.036). Patients with CD showing fistulizing behavior had significantly higher ST2 levels compared to patients with inflammatory and stricturing CD (p<0.001). Clinical activity scores of patients with UC and CD were correlated with serum ST2 levels (r=0.692, p<0.001 and r=0.242, p=0.043, respectively). Serum ST2 levels showed stepwise increases with the increasing histopathological scores of patients with UC and CD (p<0.001 for both). The present study highlights significant associations between ST2 and IBD presence and activity and demonstrates elevated serum ST2 levels in patients with active CD as a novel finding. PMID:27001944

  15. 33 CFR 334.761 - Naval Support Activity Panama City; St. Andrews Bay; restricted areas.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Naval Support Activity Panama... REGULATIONS § 334.761 Naval Support Activity Panama City; St. Andrews Bay; restricted areas. (a) The areas—(1... in this section shall be enforced by the Commanding Officer, Naval Support Activity, Panama...

  16. 33 CFR 334.761 - Naval Support Activity Panama City; St. Andrews Bay; restricted areas.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Naval Support Activity Panama... REGULATIONS § 334.761 Naval Support Activity Panama City; St. Andrews Bay; restricted areas. (a) The areas—(1... in this section shall be enforced by the Commanding Officer, Naval Support Activity, Panama...

  17. 33 CFR 334.761 - Naval Support Activity Panama City; St. Andrews Bay; restricted areas.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... City; St. Andrews Bay; restricted areas. 334.761 Section 334.761 Navigation and Navigable Waters CORPS... REGULATIONS § 334.761 Naval Support Activity Panama City; St. Andrews Bay; restricted areas. (a) The areas—(1... waterline to 30°09′57.5″ N, 085°44′37″ W; then northerly to point of origin. (2) Area BA-1. The area...

  18. 33 CFR 334.761 - Naval Support Activity Panama City; St. Andrews Bay; restricted areas.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... City; St. Andrews Bay; restricted areas. 334.761 Section 334.761 Navigation and Navigable Waters CORPS... REGULATIONS § 334.761 Naval Support Activity Panama City; St. Andrews Bay; restricted areas. (a) The areas—(1... waterline to 30°09′57.5″ N, 085°44′37″ W; then northerly to point of origin. (2) Area BA-1. The area...

  19. Results of mobile gamma scanning activities in St. Louis, Missouri

    SciTech Connect

    Rodriguez, R E; Witt, D A; Cottrell, W D; Carrier, R F

    1991-06-01

    From 1942 through approximately 1966, the Mallinckrodt Chemical Works operated four plants in St. Louis, Missouri, for the Manhattan Engineer District and the Atomic Energy Commission. A variety of production processes using uranium- and radium-bearing ore materials were performed at the plants. It is the policy of the DOE to verify that radiological conditions at such sites or facilities comply with current DOE guidelines. Guidelines for release and use of such sites have become more stringent as research has provided more information since previous cleanups. The Formerly Utilized Sites Remedial Action Program (FUSRAP) was established as part of that effort to confirm the closeout status of facilities under contract to agencies preceding DOE during early nuclear energy development. Under the FUSRAP program, the Mallinckrodt properties have been previously investigated to determine the extent of on-site radiological contamination. At the request of DOE, Oak Ridge National Laboratory (ORNL) conducted a survey in May 1990, of public roadways and suspected haul routes between the Mallinckrodt plant and storage sites in St. Louis to ensure that no residual radioactive materials were conveyed off-site. A mobile gamma scanning van with an on-board computer system was used to identify possible anomalies. Suspect areas are those displaying measurements deviating from gamma exposure rates identified as typical for radiologically unenhanced areas in the vicinity of the areas of interest. The instrumentation highlighted three anomaly locations each of which measured less than 1m{sup 2} in size. None of the slightly elevated radiation levels originated from material associated with former AEC-related processing operations in the area. The anomalies resulted from elevated concentrations of radionuclides present in phosphate fertilizers, increased thorium in road-base gravel, and emanations from the radioactive storage site near the Latty Avenue airport. 9 refs., 3 figs.

  20. 01-NIF Dedication: George Miller

    ScienceCinema

    George Miller

    2010-09-01

    The National Ignition Facility, the world's largest laser system, was dedicated at a ceremony on May 29, 2009 at Lawrence Livermore National Laboratory. These are the remarks by Lab Director George Miller.

  1. 01-NIF Dedication: George Miller

    SciTech Connect

    George Miller

    2009-07-02

    The National Ignition Facility, the world's largest laser system, was dedicated at a ceremony on May 29, 2009 at Lawrence Livermore National Laboratory. These are the remarks by Lab Director George Miller.

  2. Persistent low thymic activity and non-cardiac mortality in children with chromosome 22q11·2 microdeletion and partial DiGeorge syndrome

    PubMed Central

    Eberle, P; Berger, C; Junge, S; Dougoud, S; Büchel, E Valsangiacomo; Riegel, M; Schinzel, A; Seger, R; Güngör, T

    2009-01-01

    A subgroup of patients with 22q11·2 microdeletion and partial DiGeorge syndrome (pDGS) appears to be susceptible to non-cardiac mortality (NCM) despite sufficient overall CD4+ T cells. To detect these patients, 20 newborns with 22q11·2 microdeletion and congenital heart disease were followed prospectively for 6 years. Besides detailed clinical assessment, longitudinal monitoring of naive CD4+ and cytotoxic CD3+CD8+ T cells (CTL) was performed. To monitor thymic activity, we analysed naive platelet endothelial cell adhesion molecule-1 (CD31+) expressing CD45RA+RO−CD4+ cells containing high numbers of T cell receptor excision circle (TREC)-bearing lymphocytes and compared them with normal values of healthy children (n = 75). Comparing two age periods, low overall CD4+ and naive CD4+ T cell numbers were observed in 65%/75%, respectively, of patients in period A (< 1 year) declining to 22%/50%, respectively, of patients in period B (> 1/< 7 years). The percentage of patients with low CTLs (< P10) remained robust until school age (period A: 60%; period B: 50%). Low numbers of CTLs were associated with abnormally low naive CD45RA+RO−CD4+ T cells. A high-risk (HR) group (n = 11) and a standard-risk (SR) (n = 9) group were identified. HR patients were characterized by low numbers of both naive CD4+ and CTLs and were prone to lethal infectious and lymphoproliferative complications (NCM: four of 11; cardiac mortality: one of 11) while SR patients were not (NCM: none of nine; cardiac mortality: two of nine). Naive CD31+CD45RA+RO−CD4+, naive CD45RA+RO−CD4+ T cells as well as TRECs/106 mononuclear cells were abnormally low in HR and normal in SR patients. Longitudinal monitoring of naive CD4+ and cytotoxic T cells may help to discriminate pDGS patients at increased risk for NCM. PMID:19040613

  3. Soluble ST2: A new and promising activity marker in ulcerative colitis

    PubMed Central

    Díaz-Jiménez, David; Núñez, Lucía E; Beltrán, Caroll J; Candia, Enzo; Suazo, Cristóbal; Álvarez-Lobos, Manuel; González, María-Julieta; Hermoso, Marcela A; Quera, Rodrigo

    2011-01-01

    AIM: To correlate circulating soluble ST2 (sST2) levels with the severity of ulcerative colitis (UC) and serum levels of pro-inflammatory cytokines, and to demonstrate the predictive power of sST2 levels for differentiation between active and inactive UC. METHODS: We recruited 153 patients: 82 with UC, 26 with Crohn’s disease (CD) and 43 disease controls [non-inflammatory bowel disease (IBD)]. Subjects were excluded if they had diagnosis of asthma, autoimmune diseases or hypertension. The serum levels of sST2 and pro-inflammatory cytokines [pg/mL; median (25th-75th)] as well as clinical features, endoscopic and histological features, were subjected to analyses. The sST2 performance for discrimination between active and inactive UC, non-IBD and healthy controls (HC) was determined with regard to sensitivity and specificity, and Spearman’s rank correlation coefficient (r). To validate the method, the area under the curve (AUC) of receiver-operator characteristic (ROC) was determined (AUC, 95% CI) and the total ST2 content of the colonic mucosa in UC patients was correlated with circulating levels of sST2. RESULTS: The serum sST2 value was significantly higher in patients with active [235.80 (90.65-367.90) pg/mL] rather than inactive UC [33.19 (20.04-65.32) pg/mL], based on clinical, endoscopic and histopathological characteristics, as well as compared with non-IBD and HC (P < 0.001). The median level of sST2 in CD patients was 54.17 (35.02-122.0) pg/mL, significantly higher than that of the HC group only (P < 0.01). The cutoff was set at 74.87 pg/mL to compare active with inactive UC in a multicenter cohort of patients. Values of sensitivity, specificity, and ability to correctly classify UC, according to activity, were 83.33%, 83.33% and 83.33%, respectively. The AUC of the ROC curve to assess the ability of this molecule to discriminate between active vs inactive UC was 0.92 (0.86-0.97, P < 0.0001). The serum levels of sST2 in patients with UC significantly

  4. Activities and expression pattern of the carbohydrate sulfotransferase GlcNAc6ST-3 (I-GlcNAc6ST): functional implications.

    PubMed

    Lee, Jin Kyu; Bistrup, Annette; van Zante, Annemieke; Rosen, Steven D

    2003-04-01

    In recent years, a family of five GlcNAc-6-O-sulfotransferases, called the GlcNAc6STs, has been molecularly cloned. One of these, GlcNAc6ST-2 (originally named HEC-GlcNAc6ST or LSST), shows a very restricted expression at the mRNA level in high endothelial cells (HECs) of lymph nodes high endothelial venules (HEVs). This enzyme has been shown to be involved in elaborating the 6-sulfo sLex structure on a set of mucin-like acceptors within HECs, thus providing a critical recognition determinant for L-selectin during the process of lymphocyte homing to lymph nodes. Limited information has been available about the closely related sulfotransferase known as GlcNAc6ST-3 (I-GlcNAc6ST). Here, employing transfection experiments with a series of glycoprotein acceptors, we report that this sulfotransferase has a marked preference for sulfating O-linked sugars of mucin-type acceptors, whereas other sulfotransferases in the family (GlcNAc6ST-1, GlcNAc6ST-2) and a Gal-6-O-sulfotransferase exhibit strong activity on both mucin-type acceptors and glycoproteins with predominantly N-linked chains. PCR analysis of cDNAs derived from a panel of tissues and purified cell populations confirms the strong expression of GlcNAc6ST-3 in gut-associated tissues and extends the expression to include lymphocytes. In contrast to GlcNAc6ST-2, GlcNAc6ST-3 transcripts are present minimally, if at all, in HECs; moreover, this enzyme is not able to generate the 6-sulfo sLex epitope in transfected cells. These latter findings argue that GlcNAc6ST-3 is not involved in generating HEV-expressed ligands for L-selectin. PMID:12626414

  5. Campus Activism in the 21st Century: A Historical Framing

    ERIC Educational Resources Information Center

    Broadhurst, Christopher J.

    2014-01-01

    This chapter frames campus activism by introducing the historical movements that have been important for higher education since the 18th century to the present and exploring the connections and shared characteristics among these various movements.

  6. 75 FR 53705 - Science and Technology (S&T) Directorate; Agency Information Collection Activities: Submission...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ... SECURITY Science and Technology (S&T) Directorate; Agency Information Collection Activities: Submission for Review; Information Collection Request for the Department of Homeland Security (DHS) Science and... AGENCY: Science and Technology Directorate, DHS. ACTION: 30-day notice and request for comment....

  7. Pragmatism, Activism, and the Icy Slopes of Logic in George Reisch's Portrait of the Philosophy of Science as a Young Field

    NASA Astrophysics Data System (ADS)

    Stump, David J.

    2009-02-01

    This paper considers several models of politically engaged philosophy with the aim of provoking discussion of George Reisch’s How the Cold War Transformed Philosophy of Science. At issue is the Unity of Science movement’s conception of the philosophy of science in particular and what politically engaged philosophy of science might look like in general. The paper discusses the role that the pragmatist Sidney Hook plays in the book and considers some of the questions raised by the role that he plays: What does it mean to be a politically engaged philosopher of science? Do we want philosophy of science to be politically engaged?

  8. Observed multivariable signals of late 20th and early 21st century volcanic activity

    NASA Astrophysics Data System (ADS)

    Santer, Benjamin D.; Solomon, Susan; Bonfils, Céline; Zelinka, Mark D.; Painter, Jeffrey F.; Beltran, Francisco; Fyfe, John C.; Johannesson, Gardar; Mears, Carl; Ridley, David A.; Vernier, Jean-Paul; Wentz, Frank J.

    2015-01-01

    The relatively muted warming of the surface and lower troposphere since 1998 has attracted considerable attention. One contributory factor to this "warming hiatus" is an increase in volcanically induced cooling over the early 21st century. Here we identify the signals of late 20th and early 21st century volcanic activity in multiple observed climate variables. Volcanic signals are statistically discernible in spatial averages of tropical and near-global SST, tropospheric temperature, net clear-sky short-wave radiation, and atmospheric water vapor. Signals of late 20th and early 21st century volcanic eruptions are also detectable in near-global averages of rainfall. In tropical average rainfall, however, only a Pinatubo-caused drying signal is identifiable. Successful volcanic signal detection is critically dependent on removal of variability induced by the El Niño-Southern Oscillation.

  9. Nrf2 activation diminishes during adipocyte differentiation of ST2 cells.

    PubMed

    Chartoumpekis, Dionysios V; Ziros, Panos G; Sykiotis, Gerasimos P; Zaravinos, Apostolos; Psyrogiannis, Agathoklis I; Kyriazopoulou, Venetsana E; Spandidos, Demetrios A; Habeos, Ioannis G

    2011-11-01

    Adipocyte differentiation (adipogenesis) is a highly controlled process known to be affected, among other factors, by the redox status of the cell. Nrf2 (NFE2-related factor 2) is a transcription factor that orchestrates the expression of a battery of antioxidant and detoxification genes under both basal and stress conditions. The present study investigated the activation of Nrf2 during adipocyte differentiation using as a model the mouse bone marrow-derived ST2 cell line. Treatment of ST2 cells with a differentiation cocktail containing IBMX, indomethacin, hydrocortisone and insulin induced differentiation into adipocytes over 5 days. During adipogenesis, the intracellular glutathione redox potential, which is an indicator of oxidative stress levels, became steadily more oxidized, as shown by real-time measurement in differentiating ST2 cells stably transfected with a redox-sensitive Grx1-roGFP2 fusion protein. The nuclear abundance of Nrf2 was assessed by Western immunoblotting and its DNA binding activity by EMSA (electrophoretic mobility shift assay) performed on nuclear protein extracts prepared every 24 h. The nuclear abundance of Nrf2 continuously decreased during adipogenesis in ST2 cells. Its DNA binding activity reached a nadir during the first two days of differentiation, after which it increased slightly without approaching its initial level. The pattern of Nrf2 DNA binding corresponded to its transcriptional activity as assessed in ST2 cells stably transfected with a reporter construct bearing a Nrf2 bind site upstream of the luciferase gene. In conclusion, the activation of Nrf2 decreased significantly during adipogenesis. The observed changes might lead to increased oxidative stress levels that could facilitate the differentiation process. These findings could shed new light on the pathogenesis of obesity, in which the adipose tissue and oxidative stress play prominent roles. PMID:21805027

  10. Lunar bases and space activities of the 21st century

    SciTech Connect

    Mendell, W.W.

    1985-01-01

    The present conference gives attention to such major aspects of lunar colonization as lunar base concepts, lunar transportation, lunar science research activities, moon-based astronomical researches, lunar architectural construction, lunar materials and processes, lunar oxygen production, life support and health maintenance in lunar bases, societal aspects of lunar colonization, and the prospects for Mars colonization. Specific discussions are presented concerning the role of nuclear energy in lunar development, achromatic trajectories and the industrial scale transport of lunar resources, advanced geologic exploration from a lunar base, geophysical investigations of the moon, moon-based astronomical interferometry, the irradiation of the moon by particles, cement-based composites for lunar base construction, electrostatic concentration of lunar soil minerals, microwave processing of lunar materials, a parametric analysis of lunar oxygen production, hydrogen from lunar regolith fines, metabolic support for a lunar base, past and future Soviet lunar exploration, and the use of the moons of Mars as sources of water for lunar bases.

  11. Active thermochemistry tables : thermochemistry for the 21st century.

    SciTech Connect

    Ruscic, B.; Pinzon, R. E.; von Laszewski, G.; Kodeboyina, D.; Burcat, A.; Leahy, D.; Montoya, D.; Wagner, A. F.; Technion - Israel Inst. of Tech.; SNL; LANL

    2005-01-01

    Active Thermochemical Tables (ATcT) are a good example of a significant breakthrough in chemical science that is directly enabled by the US DOE SciDAC initiative. ATcT is a new paradigm of how to obtain accurate, reliable, and internally consistent thermochemistry and overcome the limitations that are intrinsic to the traditional sequential approach to thermochemistry. The availability of high-quality consistent thermochemical values is critical in many areas of chemistry, including the development of realistic predictive models of complex chemical environments such as combustion or the atmosphere, or development and improvement of sophisticated high-fidelity electronic structure computational treatments. As opposed to the traditional sequential evolution of thermochemical values for the chemical species of interest, ATcT utilizes the Thermochemical Network (TN) approach. This approach explicitly exposes the maze of inherent interdependencies normally ignored by the conventional treatment, and allows, inter alia, a statistical analysis of the individual measurements that define the TN. The end result is the extraction of the best possible thermochemistry, based on optimal use of all the currently available knowledge, hence making conventional tabulations of thermochemical values obsolete. Moreover, ATcT offer a number of additional features that are neither present nor possible in the traditional approach. With ATcT, new knowledge can be painlessly propagated through all affected thermochemical values. ATcT also allows hypothesis testing and evaluation, as well as discovery of weak links in the TN. The latter provides pointers to new experimental or theoretical determinations that can most efficiently improve the underlying thermochemical body of knowledge.

  12. Active thermochemical tables - thermochemistry for the 21st century.

    SciTech Connect

    Ruscic, B.; Chemistry

    2005-01-01

    Active Thermochemical Tables (ATcT) are a good example of a significant breakthrough in chemical science that is directly enabled by the US DOE SciDAC initiative. ATcT is a new paradigm of how to obtain accurate, reliable, and internally consistent thermochemistry and overcome the limitations that are intrinsic to the traditional sequential approach to thermochemistry. The availability of high-quality consistent thermochemical values is critical in many areas of chemistry, including the development of realistic predictive models of complex chemical environments such as combustion or the atmosphere, or development and improvement of sophisticated high-fidelity electronic structure computational treatments. As opposed to the traditional sequential evolution of thermochemical values for the chemical species of interest, ATcT utilizes the Thermochemical Network (TN) approach. This approach explicitly exposes the maze of inherent interdependencies normally ignored by the conventional treatment, and allows, inter alia, a statistical analysis of the individual measurements that define the TN. The end result is the extraction of the best possible thermochemistry, based on optimal use of all the currently available knowledge, hence making conventional tabulations of thermochemical values obsolete. Moreover, ATcT offer a number of additional features that are neither present nor possible in the traditional approach. With ATcT, new knowledge can be painlessly propagated through all affected thermochemical values. ATcT also allows hypothesis testing and evaluation, as well as discovery of weak links in the TN. The latter provides pointers to new experimental or theoretical determinations that can most efficiently improve the underlying thermochemical body of knowledge.

  13. A Post-Modern George.

    ERIC Educational Resources Information Center

    Hunter, Robert S.

    2000-01-01

    Presents an art project in which students create postmodern portraits of George Washington in the style of Andy Warhol's pop-art portraits. Each portrait incorporates a fact and six symbols associated with Washington. Describes the project in detail and lists the materials and project objectives. (CMK)

  14. George Morrison: Anishinaabe Expressionist Artist

    ERIC Educational Resources Information Center

    Vizenor, Gerald

    2006-01-01

    In this article, the author discusses the life and works of an Anishinaabe expressionist artist George Morrison. Morrison was an eminent expressionist painter with a singular romantic vision and an erudite sense of natural reason and liberty. He created an elusive shimmer of "endless space," the color and eternal motion of nature. The horizons he…

  15. Postmodernist Prose and George Orwell

    ERIC Educational Resources Information Center

    Roney, Stephen K.

    2002-01-01

    George Orwell, in the essay "Politics and the English Language," criticized pretentious doublespeak and technobabble that numb the consciousness and hide political power plays. Judith Butler defends the "nuanced" prose of her fellow postmodernists as necessary to convey the complexity of their thoughts. Stephen Roney contrasts the two and…

  16. Forecasts and predictions of eruptive activity at Mount St. Helens, USA: 1975-1984

    USGS Publications Warehouse

    Swanson, D.A.; Casadevall, T.J.; Dzurisin, D.; Holcomb, R.T.; Newhall, C.G.; Malone, S.D.; Weaver, C.S.

    1985-01-01

    Public statements about volcanic activity at Mount St. Helens include factual statements, forecasts, and predictions. A factual statement describes current conditions but does not anticipate future events. A forecast is a comparatively imprecise statement of the time, place, and nature of expected activity. A prediction is a comparatively precise statement of the time, place, and ideally, the nature and size of impending activity. A prediction usually covers a shorter time period than a forecast and is generally based dominantly on interpretations and measurements of ongoing processes and secondarily on a projection of past history. The three types of statements grade from one to another, and distinctions are sometimes arbitrary. Forecasts and predictions at Mount St. Helens became increasingly precise from 1975 to 1982. Stratigraphic studies led to a long-range forecast in 1975 of renewed eruptive activity at Mount St. Helens, possibly before the end of the century. On the basis of seismic, geodetic and geologic data, general forecasts for a landslide and eruption were issued in April 1980, before the catastrophic blast and landslide on 18 May 1980. All extrusions except two from June 1980 to the end of 1984 were predicted on the basis of integrated geophysical, geochemical, and geologic monitoring. The two extrusions that were not predicted were preceded by explosions that removed a substantial part of the dome, reducing confining pressure and essentially short-circuiting the normal precursors. ?? 1985.

  17. The Profession and George.

    ERIC Educational Resources Information Center

    Parker, William Riley

    1978-01-01

    An address to the MLA in 1959 defining and promoting "professional conscience" and "professional activity." The latter is defined as any work, apart from teaching and research, done for the profession. (AMH)

  18. The novel Solanum tuberosum calcium dependent protein kinase, StCDPK3, is expressed in actively growing organs.

    PubMed

    Grandellis, Carolina; Giammaria, Verónica; Bialer, Magalí; Santin, Franco; Lin, Tian; Hannapel, David J; Ulloa, Rita M

    2012-12-01

    Calcium-dependent protein kinases (CDPKs) are key components of calcium regulated signaling cascades in plants. In this work, isoform StCDPK3 from Solanum tuberosum was studied and fully described. StCDPK3 encodes a 63 kDa protein with an N-terminal variable domain (NTV), rich in prolines and glutamines, which presents myristoylation and palmitoylation consensus sites and a PEST sequence indicative of rapid protein degradation. StCDPK3 gene (circa 11 kb) is localized in chromosome 3, shares the eight exons and seven introns structure with other isoforms from subgroup IIa and contains an additional intron in the 5'UTR region. StCDPK3 expression is ubiquitous being transcripts more abundant in early elongating stolons (ES), leaves and roots, however isoform specific antibodies only detected the protein in leaf particulate extracts. The recombinant 6xHis-StCDPK3 is an active kinase that differs in its kinetic parameters and calcium requirements from StCDPK1 and 2 isoforms. In vitro, StCDPK3 undergoes autophosphorylation regardless of the addition of calcium. The StCDPK3 promoter region (circa 1,800 bp) was subcloned by genome walking and fused to GUS. Light and ABRE responsive elements were identified in the promoter region as well as elements associated to expression in roots. StCDPK3 expression was enhanced by ABA while GA decreased it. Potato transgenic lines harboring StCDPK3 promoter∷GUS construct were generated by Agrobacterium tumefaciens mediated plant transformation. Promoter activity was detected in leaves, root tips and branching points, early ES, tuber eyes and developing sprouts indicating that StCDPK3 is expressed in actively growing organs. PMID:22922879

  19. Yura-George's world line

    NASA Astrophysics Data System (ADS)

    Gamov, I. L.

    It is quite interesting and flattering for an economist to publish a paper in such a prominent astronomical journal. And taking into account the fact that the author is a relative of the great cosmologist of the 20th century does not diminish but, vice versa, increases the piquancy of the appearance of this article. You may agree, dear readers, that it is fairly difficult to avoid a temptation of addressing you on behalf of numerous admirers of George Gamow's talent, as well as of supporters of the Gamow Foundation of Moldova. Frankly speaking, I cannot get rid of a feeling that George Gamow himself, through some genetic "channels" known to him alone, is pushing me to tell about him, for he was famous for all kinds of tricks.

  20. George Minot and Pernicious Anemia.

    PubMed

    Dhungat, J V Pai

    2015-08-01

    George Minot (1885-1950) was born in Boston, Massachusetts. He was great grandson of James Jackson, co-founder of Massachusetts General Hospital in 1821. Graduating from Harvard College he enrolled at Harvard Medical School and obtained his MD in 1912. As a house pupil (intern) at the hospital he became interested in diseases of the blood and began taking meticulous histories of dietary habits of patients with anemia. PMID:27604448

  1. The dihydrolipoamide dehydrogenase of Aeromonas caviae ST exhibits NADH-dependent tellurite reductase activity.

    PubMed

    Castro, Miguel E; Molina, Roberto; Díaz, Waldo; Pichuantes, Sergio E; Vásquez, Claudio C

    2008-10-10

    Potassium tellurite (K(2)TeO(3)) is extremely toxic for most forms of life and only a limited number of organisms are naturally resistant to the toxic effects of this compound. Crude extracts prepared from the environmental isolate Aeromonas caviae ST catalize the in vitro reduction of TeO32- in a NADH-dependent reaction. Upon fractionation by ionic exchange column chromatography three major polypeptides identified as the E1, E2, and E3 components of the pyruvate dehydrogenase (PDH) complex were identified in fractions exhibiting tellurite-reducing activity. Tellurite reductase and pyruvate dehydrogenase activities co-eluted from a Sephadex gel filtration column. To determine which component(s) of the PDH complex has tellurite reductase activity, the A. caviae ST structural genes encoding for E1 (aceE), E2 (aceF), and E3 (lpdA) were independently cloned and expressed in Escherichia coli and their gene products purified. Results indicated that tellurite reductase activity lies almost exclusively in the E3 component, dihydrolipoamide dehydrogenase. The E3 component of the PDH complex from E. coli, Zymomonas mobilis, Streptococcus pneumoniae, and Geobacillus stearothermophilus also showed NADH-dependent tellurite reductase in vitro suggesting that this enzymatic activity is widely distributed among microorganisms. PMID:18675788

  2. EAARL topography: George Washington Birthplace National Monument

    USGS Publications Warehouse

    Brock, John C.; Wright, C. Wayne; Patterson, Matt; Nayegandhi, Amar; Patterson, Judd

    2007-01-01

    This Web site contains Lidar-derived topography (first return and bare earth) maps and GIS files for George Washington Birthplace National Monument in Virginia. These lidar-derived topography maps were produced as a collaborative effort between the U.S. Geological Survey (USGS) Coastal and Marine Geology Program, FISC St. Petersburg, the National Park Service (NPS), Northeast Coastal and Barrier Network, Inventory and Monitoring Program, and the National Aeronautics and Space Administration (NASA) Wallops Flight Facility. One objective of this research is to create techniques to survey coral reefs and barrier islands for the purposes of geomorphic change studies, habitat mapping, ecological monitoring, change detection, and event assessment. As part of this project, data from an innovative instrument under development at the NASA Wallops Flight Facility, the NASA Experimental Airborne Advanced Research Lidar (EAARL) are being used. This sensor has the potential to make significant contributions in this realm for measuring subaerial and submarine topography wthin cross-environment surveys. High spectral resolution, water-column correction, and low costs were found to be key factors in providing accurate and affordable imagery to coastal resource managers.

  3. George Walker, 1926-2005

    NASA Astrophysics Data System (ADS)

    Self, Stephen

    2006-08-01

    George Patrick Leonard Walker, an outstanding and multi-faceted geologist andone of the most influential volcanologists in the world, died on 17 January 2005, at the age of 78. He was born in London on 2 March1926 and grew up mainly in Northern Ireland. He read geology for B.Sc. honors and M.Sc. degrees at Queens University in Belfast,Northern Ireland, and completed his training with a Ph.D. in mineralogy from Leeds Universityin England, which he received in 1956. By then, he had already been appointed, in 1954, to a lectureship at Imperial College London.

  4. George Bernard Shaw on Anesthesia.

    PubMed

    Alston, Theodore A; Carr, Daniel B

    2016-04-01

    Recipient of the 1925 Nobel Prize in Literature, George Bernard Shaw (1856-1950) was an influential critic of the health care establishment in the United Kingdom. Although skeptical of many medical and surgical procedures of the early 20th century, he respected the value of anesthesia, and he advocated its administration by Frederick W. Axham, a medical doctor whose registration was suspended as punishment for providing anesthesia for a bonesetting procedure. In 1924, when a friend needed surgery, Shaw offered to pay the extra fee for the optional anesthesia. PMID:27080502

  5. Skylab Concept by George Mueller

    NASA Technical Reports Server (NTRS)

    1966-01-01

    This is a sketch of Skylab, as drawn by George E. Mueller, NASA associate administrator for Manned Space Flight. This concept drawing was created at a meeting at the Marshall Space Flight Center on August 19, 1966. The image details the station's major elements. In 1970, the station became known as Skylab. Three manned Skylab missions (Skylab 2 in May 1973; Skylab 3 in July 1973; and Skylab 4 in November 1973) were flown on which experiments were conducted in:space science, earth resources, life sciences, space technology, and student projects.

  6. Autosomal ichthyosis with hypotrichosis syndrome displays low matriptase proteolytic activity and is phenocopied in ST14 hypomorphic mice.

    PubMed

    List, Karin; Currie, Brooke; Scharschmidt, Tiffany C; Szabo, Roman; Shireman, Jessica; Molinolo, Alfredo; Cravatt, Benjamin F; Segre, Julia; Bugge, Thomas H

    2007-12-14

    Human autosomal recessive ichthyosis with hypotrichosis (ARIH) is an inherited disorder recently linked to homozygosity for a point mutation in the ST14 gene that causes a G827R mutation in the matriptase serine protease domain (G216 in chymotrypsin numbering). Here we show that human G827R matriptase has strongly reduced proteolytic activity toward small molecule substrates, as well as toward its candidate epidermal target, prostasin. To further investigate the possible contribution of low matriptase activity to ARIH, we generated an ST14 hypomorphic mouse strain that displays a 100-fold reduction in epidermal matriptase mRNA levels. Interestingly, unlike ST14 null mice, ST14 hypomorphic mice were viable and fertile but displayed a spectrum of abnormalities that strikingly resembled ARIH. Thus, ST14 hypomorphic mice developed hyperproliferative and retention ichthyosis with impaired desquamation, hypotrichosis with brittle, thin, uneven, and sparse hair, and tooth defects. Biochemical analysis of ST14 hypomorphic epidermis revealed reduced prostasin proteolytic activation and profilaggrin proteolytic processing, compatible with a primary role of matriptase in this process. This work strongly indicates that reduced activity of a matriptase-prostasin proteolytic cascade is the etiological origin of human ARIH and provides an important mouse model for the exploration of matriptase function in ARIH, as well as multiple other physiological and pathological processes. PMID:17940283

  7. Association of Single Nucleotide Polymorphisms in the ST3GAL4 Gene with VWF Antigen and Factor VIII Activity.

    PubMed

    Song, Jaewoo; Xue, Cheng; Preisser, John S; Cramer, Drake W; Houck, Katie L; Liu, Guo; Folsom, Aaron R; Couper, David; Yu, Fuli; Dong, Jing-Fei

    2016-01-01

    VWF is extensively glycosylated with biantennary core fucosylated glycans. Most N-linked and O-linked glycans on VWF are sialylated. FVIII is also glycosylated, with a glycan structure similar to that of VWF. ST3GAL sialyltransferases catalyze the transfer of sialic acids in the α2,3 linkage to termini of N- and O-glycans. This sialic acid modification is critical for VWF synthesis and activity. We analyzed genetic and phenotypic data from the Atherosclerosis Risk in Communities (ARIC) study for the association of single nucleotide polymorphisms (SNPs) in the ST3GAL4 gene with plasma VWF levels and FVIII activity in 12,117 subjects. We also analyzed ST3GAL4 SNPs found in 2,535 subjects of 26 ethnicities from the 1000 Genomes (1000G) project for ethnic diversity, SNP imputation, and ST3GAL4 haplotypes. We identified 14 and 1,714 ST3GAL4 variants in the ARIC GWAS and 1000G databases respectively, with 46% being ethnically diverse in their allele frequencies. Among the 14 ST3GAL4 SNPs found in ARIC GWAS, the intronic rs2186717, rs7928391, and rs11220465 were associated with VWF levels and with FVIII activity after adjustment for age, BMI, hypertension, diabetes, ever-smoking status, and ABO. This study illustrates the power of next-generation sequencing in the discovery of new genetic variants and a significant ethnic diversity in the ST3GAL4 gene. We discuss potential mechanisms through which these intronic SNPs regulate ST3GAL4 biosynthesis and the activity that affects VWF and FVIII. PMID:27584569

  8. George Peabody and the Spirit of America.

    ERIC Educational Resources Information Center

    Parker, Franklin

    1994-01-01

    One of a collection of articles on philanthropist George Peabody tells the story of two bronze doors made by sculptor Louis Amateis for the U.S. Capitol. The doors include a panel entitled Apotheosis of America that captures Amateis' vision of the spirit of America and includes the figures of George Peabody and other historic personages. (SM)

  9. Design of the recoil mass separator St. George

    NASA Astrophysics Data System (ADS)

    Couder, M.; Berg, G. P. A.; Görres, J.; LeBlanc, P. J.; Lamm, L. O.; Stech, E.; Wiescher, M.; Hinnefeld, J.

    2008-03-01

    A recoil mass separator has been designed for the purpose of studying low energy (α,γ) reactions in inverse kinematics for beam masses up to about A=40. Their reaction rates are of importance for our understanding of energy production and nucleosynthesis during stellar and explosive helium burning. The reactions take place in a windowless He gas target at the beginning of the separator which consists of three sections. The first section selects the most abundant charge state. The Wien filter in the second section efficiently separates the intense beam from the few reaction products. In the last section the reaction products are focused into a detector system consisting of time pickup and energy detectors. In order to accept the complete kinematic cone of recoil particles for energies as low as reasonably possible we specified a large circular angular acceptance of ±40 mrad. This requires a careful minimization of higher-order aberrations. The present system has been designed to allow for a future upgrade to extend the experimental program to the analysis of (p,γ) reactions.

  10. Diagnosis and outcome of anorexia nervosa: the St George's view.

    PubMed Central

    Crisp, A H

    1977-01-01

    Anorexia nervosa has been viewed here as a defensive biologically regressed posture pivoting around the events of puberty and reflecting primary gain. There is rarely any secondary gain - on the contrary life is miserable though still usually possible. The disorder is rooted in psychobiological mechanisms within the individual and in individual and family psychopathology concerning the meaning of body weight and fatness, evoked by the proband's adolescence and its maturational challenges. There are many identifiable 'risk factors' that can influence the evolution of the condition. Treatment requires a combined behavioural and psychotherapeutic approach involving special medical and nursing and psychotherapeutic skills. PMID:896784

  11. Astronaut George Nelson uses one-G version of MMU to prepare for EVA

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Astronaut George D. Nelson, 41-C mission specialist, uses a one-G version of manned maneuvering unit (MMU) to prepare for his upcoming extravehicular activity (EVA). The simulator is located in JSC's avionics systems laboratory.

  12. Disordered IL-33/ST2 activation in decidualizing stromal cells prolongs uterine receptivity in women with recurrent pregnancy loss.

    PubMed

    Salker, Madhuri S; Nautiyal, Jaya; Steel, Jennifer H; Webster, Zoe; Sućurović, Sandra; Nicou, Marilena; Singh, Yogesh; Lucas, Emma S; Murakami, Keisuke; Chan, Yi-Wah; James, Sean; Abdallah, Yazan; Christian, Mark; Croy, B Anne; Mulac-Jericevic, Biserka; Quenby, Siobhan; Brosens, Jan J

    2012-01-01

    Decidualization renders the endometrium transiently receptive to an implanting blastocyst although the underlying mechanisms remain incompletely understood. Here we show that human endometrial stromal cells (HESCs) rapidly release IL-33, a key regulator of innate immune responses, upon decidualization. In parallel, differentiating HESCs upregulate the IL-33 transmembrane receptor ST2L and other pro-inflammatory mediators before mounting a profound anti-inflammatory response that includes downregulation of ST2L and increased expression of the soluble decoy receptor sST2. We demonstrate that HESCs secrete factors permissive of embryo implantation in mice only during the pro-inflammatory phase of the decidual process. IL-33 knockdown in undifferentiated HESCs was sufficient to abrogate this pro-inflammatory decidual response. Further, sequential activation of the IL-33/ST2L/sST2 axis was disordered in decidualizing HESCs from women with recurrent pregnancy loss. Signals from these cultures prolonged the implantation window but also caused subsequent pregnancy failure in mice. Thus, Il-33/ST2 activation in HESCS drives an autoinflammatory response that controls the temporal expression of receptivity genes. Failure to constrain this response predisposes to miscarriage by allowing out-of-phase implantation in an unsupportive uterine environment. PMID:23300625

  13. Downscaling CMIP5 climate models shows increased tropical cyclone activity over the 21st century

    PubMed Central

    Emanuel, Kerry A.

    2013-01-01

    A recently developed technique for simulating large [O(104)] numbers of tropical cyclones in climate states described by global gridded data is applied to simulations of historical and future climate states simulated by six Coupled Model Intercomparison Project 5 (CMIP5) global climate models. Tropical cyclones downscaled from the climate of the period 1950–2005 are compared with those of the 21st century in simulations that stipulate that the radiative forcing from greenhouse gases increases by over preindustrial values. In contrast to storms that appear explicitly in most global models, the frequency of downscaled tropical cyclones increases during the 21st century in most locations. The intensity of such storms, as measured by their maximum wind speeds, also increases, in agreement with previous results. Increases in tropical cyclone activity are most prominent in the western North Pacific, but are evident in other regions except for the southwestern Pacific. The increased frequency of events is consistent with increases in a genesis potential index based on monthly mean global model output. These results are compared and contrasted with other inferences concerning the effect of global warming on tropical cyclones. PMID:23836646

  14. Downscaling CMIP5 climate models shows increased tropical cyclone activity over the 21st century.

    PubMed

    Emanuel, Kerry A

    2013-07-23

    A recently developed technique for simulating large [O(10(4))] numbers of tropical cyclones in climate states described by global gridded data is applied to simulations of historical and future climate states simulated by six Coupled Model Intercomparison Project 5 (CMIP5) global climate models. Tropical cyclones downscaled from the climate of the period 1950-2005 are compared with those of the 21st century in simulations that stipulate that the radiative forcing from greenhouse gases increases by over preindustrial values. In contrast to storms that appear explicitly in most global models, the frequency of downscaled tropical cyclones increases during the 21st century in most locations. The intensity of such storms, as measured by their maximum wind speeds, also increases, in agreement with previous results. Increases in tropical cyclone activity are most prominent in the western North Pacific, but are evident in other regions except for the southwestern Pacific. The increased frequency of events is consistent with increases in a genesis potential index based on monthly mean global model output. These results are compared and contrasted with other inferences concerning the effect of global warming on tropical cyclones. PMID:23836646

  15. Georges Bank Winds: 1975 19971

    NASA Astrophysics Data System (ADS)

    Manning, James; Strout, Glenn

    Twenty-three years (1975-1997) of anemometer records from the four NOAA buoys located near Georges Bank are examined. While the individual buoy records have occasional gaps due to instrument breakdowns and the buoys deployments were limited to certain years, the combination of the four buoys provides a nearly continuous series of observed wind. After correcting for different anemometer heights, sea-surface wind stress is calculated by the neutral stability method of Large and Pond J. Phys. Ocean 11 (1981) 324. Weekly mean stress is plotted for the entire period. Significant coherence (0.72-0.92) was found between sites with very little phase or gain for the 2-10 day storm-band period. An offshore increase of ˜0.006 Pa/100 km is detected in the mean stress for the Winter/Fall seasons. The complex correlation coefficients (calculated as a single measure of coherence across all frequency bands) ranges from 0.68 to 0.90. Other sources of wind data are discussed including the Fleet Numerical Meteorology and Oceanography Center's (FNMOC) estimates from pressure observations, the Comprehensive Ocean Atmosphere Data Set (COADS) from ship observations, and NOAA's National Center for Environmental Prediction (NCEP) recent model/data assimilation. For purposes of representing storm-band frequency, the FNMOC winds account for more than 80% of the variability in the buoy record and they provide a continuous surface wind estimate for the Georges Bank region back to 1967. However, the intensified wind stress as a function of distance offshore, as detected by both the buoys and COADS , is not detected in the FMNOC records. Also, a counterclockwise rotation of 19 max° is needed (in addition to the standard 15°) to correct the FMNOC winds for the atmospheric boundary layer. Recent NCEP products provide a finer scale spatial coverage of the wind field and are a potential source of boundary forcing for coastal ocean circulation models.

  16. Fibrin(ogen)olytic and antiplatelet activities of a subtilisin-like protease from Solanum tuberosum (StSBTc-3).

    PubMed

    Pepe, Alfonso; Frey, María Eugenia; Muñoz, Fernando; Fernández, María Belén; Pedraza, Anabela; Galbán, Gustavo; García, Diana Noemí; Daleo, Gustavo Raúl; Guevara, María Gabriela

    2016-06-01

    Plant serine proteases have been widely used in food science and technology as well as in medicine. In this sense, several plant serine proteases have been proposed as potential anti-coagulants and anti-platelet agents. Previously, we have reported the purification and identification of a plant serine protease from Solanum tuberosum leaves. This potato enzyme, named as StSBTc-3, has a molecular weight of 72 kDa and it was characterized as a subtilisin like protease. In this work we determine and characterize the biochemical and medicinal properties of StSBTc-3. Results obtained show that, like the reported to other plant serine proteases, StSBTc-3 is able to degrade all chains of human fibrinogen and to produces fibrin clot lysis in a dose dependent manner. The enzyme efficiently hydrolyzes β subunit followed by partially hydrolyzed α and γ subunits of human fibrinogen. Assays performed to determine StSBTc-3 substrate specificity using oxidized insulin β-chain as substrate, show seven cleavage sites: Asn3-Gln4; Cys7-Gly8; Glu13-Ala14; Leu15-Tyr16; Tyr16-Leu17; Arg22-Gly23 and Phe25-Tyr26, all of them were previously reported for other serine proteases with fibrinogenolytic activity. The maximum StSBTc-3 fibrinogenolytic activity was determined at pH 8.0 and at 37 C. Additionally, we demonstrate that StSBTc-3 is able to inhibit platelet aggregation and is unable to exert cytotoxic activity on human erythrocytes in vitro at all concentrations assayed. These results suggest that StSBTc-3 could be evaluated as a new agent to be used in the treatment of thromboembolic disorders such as strokes, pulmonary embolism and deep vein thrombosis. PMID:27039890

  17. The Second Conference on Lunar Bases and Space Activities of the 21st Century, volume 2

    NASA Technical Reports Server (NTRS)

    Mendell, Wendell W. (Editor); Alred, John W. (Editor); Bell, Larry S. (Editor); Cintala, Mark J. (Editor); Crabb, Thomas M. (Editor); Durrett, Robert H. (Editor); Finney, Ben R. (Editor); Franklin, H. Andrew (Editor); French, James R. (Editor); Greenberg, Joel S. (Editor)

    1992-01-01

    These 92 papers comprise a peer-reviewed selection of presentations by authors from NASA, the Lunar and Planetary Institute (LPI), industry, and academia at the Second Conference on Lunar Bases and Space Activities of the 21st Century. These papers go into more technical depth than did those published from the first NASA-sponsored symposium on the topic, held in 1984. Session topics included the following: (1) design and operation of transportation systems to, in orbit around, and on the Moon; (2) lunar base site selection; (3) design, architecture, construction, and operation of lunar bases and human habitats; (4) lunar-based scientific research and experimentation in astronomy, exobiology, and lunar geology; (5) recovery and use of lunar resources; (6) environmental and human factors of and life support technology for human presence on the Moon; and (7) program management of human exploration of the Moon and space.

  18. The Second Conference on Lunar Bases and Space Activities of the 21st Century, volume 1

    NASA Technical Reports Server (NTRS)

    Mendell, Wendell W. (Editor); Alred, John W. (Editor); Bell, Larry S. (Editor); Cintala, Mark J. (Editor); Crabb, Thomas M. (Editor); Durrett, Robert H. (Editor); Finney, Ben R. (Editor); Franklin, H. Andrew (Editor); French, James R. (Editor); Greenberg, Joel S. (Editor)

    1992-01-01

    These papers comprise a peer-review selection of presentations by authors from NASA, LPI industry, and academia at the Second Conference (April 1988) on Lunar Bases and Space Activities of the 21st Century, sponsored by the NASA Office of Exploration and the Lunar Planetary Institute. These papers go into more technical depth than did those published from the first NASA-sponsored symposium on the topic, held in 1984. Session topics covered by this volume include (1) design and operation of transportation systems to, in orbit around, and on the Moon, (2) lunar base site selection, (3) design, architecture, construction, and operation of lunar bases and human habitats, and (4) lunar-based scientific research and experimentation in astronomy, exobiology, and lunar geology.

  19. The Second Conference on Lunar Bases and Space Activities of the 21st Century, volume 1

    SciTech Connect

    Mendell, W.W.; Alred, J.W.; Bell, L.S.; Cintala, M.J.; Crabb, T.M.; Durrett, R.H.; Finney, B.R.; Franklin, H.A.; French, J.R.; Greenberg, J.S.

    1992-09-01

    These papers comprise a peer-review selection of presentations by authors from NASA, LPI industry, and academia at the Second Conference (April 1988) on Lunar Bases and Space Activities of the 21st Century, sponsored by the NASA Office of Exploration and the Lunar Planetary Institute. These papers go into more technical depth than did those published from the first NASA-sponsored symposium on the topic, held in 1984. Session topics covered by this volume include (1) design and operation of transportation systems to, in orbit around, and on the Moon, (2) lunar base site selection, (3) design, architecture, construction, and operation of lunar bases and human habitats, and (4) lunar-based scientific research and experimentation in astronomy, exobiology, and lunar geology. Separate abstracts have been prepared for articles from this report.

  20. The second conference on lunar bases and space activities of the 21st Century, volume 2

    SciTech Connect

    Mendell, W.W.; Alred, J.W.; Bell, L.S.; Cintala, M.J.; Crabb, T.M.; Durrett, R.H.; Finney, B.R.; Franklin, H.A.; French, J.R.; Greenberg, J.S.

    1992-09-01

    These 92 papers comprise a peer-reviewed selection of presentations by authors from NASA, the Lunar and Planetary Institute (LPI), industry, and academia at the Second Conference on Lunar Bases and Space Activities of the 21st Century. These papers go into more technical depth than did those published from the first NASA-sponsored symposium on the topic, held in 1984. Session topics included the following: (1) design and operation of transportation systems to, in orbit around, and on the Moon; (2) lunar base site selection; (3) design, architecture, construction, and operation of lunar bases and human habitats; (4) lunar-based scientific research and experimentation in astronomy, exobiology, and lunar geology; (5) recovery and use of lunar resources; (6) environmental and human factors of and life support technology for human presence on the Moon; and (7) program management of human exploration of the Moon and space. Separate abstracts have been prepared for articles in this report.

  1. Anxiolytic and antidepressant-like activities of the novel and potent non-imidazole histamine H₃ receptor antagonist ST-1283.

    PubMed

    Bahi, Amine; Schwed, Johannes Stephan; Walter, Miriam; Stark, Holger; Sadek, Bassem

    2014-01-01

    Previous studies have suggested a potential link between histamine H₃ receptors (H₃R) signaling and anxiolytic-like and antidepressant-like effects. The aim of this study was to investigate the acute effects of ST-1283, a novel H₃R antagonist, on anxiety-related and depression-related behaviors in comparison with those of diazepam and fluoxetine. The effects of ST-1283 were evaluated using the elevated plus maze test, open field test, marbles burying test, tail suspension test, novelty suppressed feeding test, and forced swim test in male C57BL/6 mice. The results showed that, like diazepam, ST-1283 (7.5 mg/kg) significantly modified all the parameters observed in the elevated plus maze test. In addition, ST-1283 significantly increased the amount of time spent in the center of the arena without altering general motor activity in the open field test. In the same vein, ST-1283 reduced the number of buried marbles as well as time spent digging in the marbles burying test. The tail suspension test and forced swim test showed that ST-1283 was able to reduce immobility time, like the recognized antidepressant drug fluoxetine. In the novelty suppressed feeding test, treatment with ST-1283 decreased latency to feed with no effect on food intake in the home cage. Importantly, pretreatment with the H₃R agonist R-α-methylhistamine abrogated the anxiolytic and antidepressant effects of ST-1283. Taken together, the present series of studies demonstrates the novel effects of this newly synthesized H₃R antagonist in a number of preclinical models of psychiatric disorders and highlights the histaminergic system as a potential therapeutic target for the treatment of anxiety-related and depression-related disorders. PMID:24920886

  2. George Chester Stone (1924-2013).

    PubMed

    Adler, Nancy

    2014-01-01

    George Chester Stone was born February 21, 1924, and died on July 13, 2013. A quiet revolutionary, George was a founder of the field of health psychology. George played critical roles conceptualizing the field of health psychology, charting its bounds and potential, promulgating guidelines for training, founding the first doctoral program in health psychology, editing influential volumes defining the new field, launching the flagship journal for the field, and establishing a home for the field within APA. He was able to accomplish all this through his talent for working collaboratively. PMID:25046719

  3. Highly electronegative LDL from patients with ST-elevation myocardial infarction triggers platelet activation and aggregation

    PubMed Central

    Chan, Hua-Chen; Ke, Liang-Yin; Chu, Chih-Sheng; Lee, An-Sheng; Shen, Ming-Yi; Cruz, Miguel A.; Hsu, Jing-Fang; Cheng, Kai-Hung; Chan, Hsiu-Chuan Bonnie; Lu, Jonathan; Lai, Wen-Ter; Sawamura, Tatsuya; Sheu, Sheng-Hsiung

    2013-01-01

    Platelet activation and aggregation underlie acute thrombosis that leads to ST-elevation myocardial infarction (STEMI). L5—highly electronegative low-density lipoprotein (LDL)—is significantly elevated in patients with STEMI. Thus, we examined the role of L5 in thrombogenesis. Plasma LDL from patients with STEMI (n = 30) was chromatographically resolved into 5 subfractions (L1-L5) with increasing electronegativity. In vitro, L5 enhanced adenosine diphosphate–stimulated platelet aggregation twofold more than did L1 and induced platelet-endothelial cell (EC) adhesion. L5 also increased P-selectin expression and glycoprotein (GP)IIb/IIIa activation and decreased cyclic adenosine monophosphate levels (n = 6, P < .01) in platelets. In vivo, injection of L5 (5 mg/kg) into C57BL/6 mice twice weekly for 6 weeks shortened tail bleeding time by 43% (n = 3; P < .01 vs L1-injected mice) and increased P-selectin expression and GPIIb/IIIa activation in platelets. Pharmacologic blockade experiments revealed that L5 signals through platelet-activating factor receptor and lectin-like oxidized LDL receptor-1 to attenuate Akt activation and trigger granule release and GPIIb/IIIa activation via protein kinase C-α. L5 but not L1 induced tissue factor and P-selectin expression in human aortic ECs (P < .01), thereby triggering platelet activation and aggregation with activated ECs. These findings indicate that elevated plasma levels of L5 may promote thrombosis that leads to STEMI. PMID:24030386

  4. Modeling the Magnetic and Thermal Structure of Active Regions: 1st Year 1st Semi-Annual Progress Report

    NASA Technical Reports Server (NTRS)

    Mikic, Zoran

    2003-01-01

    This report covers technical progress during the first six months of the first year of NASA SR&T contract "Modeling the Magnetic and Thermal Structure of Active Regions", NASW-03008, between NASA and Science Applications International Corporation, and covers the period January 14, 2003 to July 13, 2003. Under this contract SAIC has conducted research into theoretical modeling of the properties of active regions using the MHD model.

  5. George Orwell, Grunts and Freshman Composition.

    ERIC Educational Resources Information Center

    Stine, Peter

    1983-01-01

    Uses the Vietnamese War as a metaphor for student and instructor approaches to language in composition classes. Explores George Orwell's "Politics and the English Language" in its relationship to the rhetoric surrounding United States intervention. (MM)

  6. Temporal variation of mass-wasting activity in Mount St. Helens crater, Washington, U. S. A. indicated by seismic activity

    SciTech Connect

    Mills, H.H. )

    1991-11-01

    In the crater of Mount St. Helens, formed during the eruption of 18 May 1980, thousands of rockfalls may occur in a single day, and some rock and dirty-snow avalanches have traveled more than 1 km from their source. Because most seismic activity in the crater is produced by mass wasting, the former can be used to monitor the latter. The number and amplitude of seismic events per unit time provide a generalized measure of mass-wasting activity. In this study 1-min averages of seismic amplitudes were used as an index of rockfall activity during summer and early fall. Plots of this index show the diurnal cycle of rockfall activity and establish that the peak in activity occurs in mid to late afternoon. A correlation coefficient of 0.61 was found between daily maximum temperature and average seismic amplitude, although this value increases to 0.72 if a composite temperature variable that includes the maximum temperature of 1 to 3 preceding days as well as the present day is used. Correlation with precipitation is much weaker.

  7. George Combe and common sense.

    PubMed

    Dyde, Sean

    2015-06-01

    This article examines the history of two fields of enquiry in late eighteenth- and early nineteenth-century Scotland: the rise and fall of the common sense school of philosophy and phrenology as presented in the works of George Combe. Although many previous historians have construed these histories as separate, indeed sometimes incommensurate, I propose that their paths were intertwined to a greater extent than has previously been given credit. The philosophy of common sense was a response to problems raised by Enlightenment thinkers, particularly David Hume, and spurred a theory of the mind and its mode of study. In order to succeed, or even to be considered a rival of these established understandings, phrenologists adapted their arguments for the sake of engaging in philosophical dispute. I argue that this debate contributed to the relative success of these groups: phrenology as a well-known historical subject, common sense now largely forgotten. Moreover, this history seeks to question the place of phrenology within the sciences of mind in nineteenth-century Britain. PMID:25921681

  8. Adequacy of environmental information for outer continental shelf oil and gas decisions: Georges Bank. Final report

    SciTech Connect

    Not Available

    1991-01-01

    Georges Bank, a large, shallow marine bank with important fishery resources and possibly important oil and gas resources, lies east of Massachusetts in the territorial waters of both the United States and Canada. The Department of the Interior has planned since 1974 to lease parts of the north Atlantic outer continental shelf (OCS)--including part of Georges Bank--for oil and gas exploration. As a result of public concern about the environmental impacts of oil and gas production on the U.S. OCS, Congress declared a moratorium on drilling on Georges Bank and an area to the southwest. The report--by the NRC's Committee to Review the Outer Continental Shelf Environmental Studies Program and its panels on physical oceanography, ecology, and socioeconomics--reviews the adequacy of information bearing on the potential environmental impacts of OCS oil and gas activities for the Georges Bank sale area.

  9. Isolation and characterization of a Solanum tuberosum subtilisin-like protein with caspase-3 activity (StSBTc-3).

    PubMed

    Fernández, María Belén; Daleo, Gustavo Raúl; Guevara, María Gabriela

    2015-01-01

    Plant proteases with caspase-like enzymatic activity have been widely studied during the last decade. Previously, we have reported the presence and induction of caspase-3 like activity in the apoplast of potato leaves during Solanum tuberosum- Phytophthora infestans interaction. In this work we have purified and identified a potato extracellular protease with caspase-3 like enzymatic activity from potato leaves infected with P. infestans. Results obtained from the size exclusion chromatography show that the isolated protease is a monomeric enzyme with an estimated molecular weight of 70 kDa approximately. Purified protease was analyzed by MALDI-TOF MS, showing a 100% of sequence identity with the deduced amino acid sequence of a putative subtilisin-like protease from S. tuberosum (Solgenomics protein ID: PGSC0003DMP400018521). For this reason the isolated protease was named as StSBTc-3. This report constitutes the first evidence of isolation and identification of a plant subtilisin-like protease with caspase-3 like enzymatic activity. In order to elucidate the possible function of StSBTc-3 during plant pathogen interaction, we demonstrate that like animal caspase-3, StSBTc-3 is able to produce in vitro cytoplasm shrinkage in plant cells and to induce plant cell death. This result suggest that, StSBTc-3 could exert a caspase executer function during potato- P. infestans interaction, resulting in the restriction of the pathogen spread during plant-pathogen interaction. PMID:25486023

  10. Use of Emerging Technologies to Assess Differences in Outdoor Physical Activity in St. Louis, Missouri

    PubMed Central

    Adlakha, Deepti; Budd, Elizabeth L.; Gernes, Rebecca; Sequeira, Sonia; Hipp, James A.

    2014-01-01

    Introduction: Abundant evidence shows that regular physical activity (PA) is an effective strategy for preventing obesity in people of diverse socioeconomic status (SES) and racial groups. The proportion of PA performed in parks and how this differs by proximate neighborhood SES has not been thoroughly investigated. The present project analyzes online public web data feeds to assess differences in outdoor PA by neighborhood SES in St. Louis, MO, USA. Methods: First, running and walking routes submitted by users of the website MapMyRun.com were downloaded. The website enables participants to plan, map, record, and share their exercise routes and outdoor activities like runs, walks, and hikes in an online database. Next, the routes were visually illustrated using geographic information systems. Thereafter, using park data and 2010 Missouri census poverty data, the odds of running and walking routes traversing a low-SES neighborhood, and traversing a park in a low-SES neighborhood were examined in comparison to the odds of routes traversing higher-SES neighborhoods and higher-SES parks. Results: Results show that a majority of running and walking routes occur in or at least traverse through a park. However, this finding does not hold when comparing low-SES neighborhoods to higher-SES neighborhoods in St. Louis. The odds of running in a park in a low-SES neighborhood were 54% lower than running in a park in a higher-SES neighborhood (OR = 0.46, CI = 0.17–1.23). The odds of walking in a park in a low-SES neighborhood were 17% lower than walking in a park in a higher-SES neighborhood (OR = 0.83, CI = 0.26–2.61). Conclusion: The novel methods of this study include the use of inexpensive, unobtrusive, and publicly available web data feeds to examine PA in parks and differences by neighborhood SES. Emerging technologies like MapMyRun.com present significant advantages to enhance tracking of user-defined PA across large geographic and temporal settings

  11. George Glasson and George Bogg's Prospects on the Environmental Friendly Relationship and Ecojustice

    ERIC Educational Resources Information Center

    Dopico, Eduardo

    2011-01-01

    This rejoinder to George Glasson and George Bogg's papers provides additional conversation for considering the idea that we try to develop: leaving the classroom to continue teaching. Converting the teaching-learning process into research experiences brings our students not only scientific knowledge, but also an understanding of the research…

  12. The Development of the George B. Pegram Award

    NASA Astrophysics Data System (ADS)

    McCay, Myron S.

    1997-11-01

    The George B. Pegram Award for Excellence in the Teaching of Physics was developed by a representative group of SESAPS members over a period of eight years with outstanding contributions as follows: Jesse Beams, APS President, with the advice of Mark Zemansky, AAPT, chose George B. Pegram as the honoree, in view of his excellent teaching career at Columbia University, his graduation from Trinity College--now Duke University, his long period of service as Treasurer of APS, and his active support of the special training program at ORAU; Earle Plyler with the assistance of Edward Burke, Jr., prepared the selection criteria for the recipients of the award; Walter Gordy coordinated the APS approval and initiated the financing of the program; Howard Carr raised the first funds and prepared the initial certificates; William G. Pollard joined the committee and completed the early funding, while preparing the formal certificate and medal; Dr. Vernet Eaton, AAPT President, stimulated the program when he urged the nomination of SESAPS members for the Oersted Award. After his lectures at the 1955 Gainesville meeting, Wendell Holladay instructed the committee to report its recommendations at the next SESAPS meeting. In 1969 SESAPS approved the George B. Pegram Award.

  13. Development of a Rotor-Body Coupled Analysis for an Active Mount Aeroelastic Rotor Testbed. Degree awarded by George Washington Univ., May 1996

    NASA Technical Reports Server (NTRS)

    Wilbur, Matthew L.

    1998-01-01

    At the Langley Research Center an active mount rotorcraft testbed is being developed for use in the Langley Transonic Dynamics Tunnel. This testbed, the second generation version of the Aeroelastic Rotor Experimental System (ARES-II), can impose rotor hub motions and measure the response so that rotor-body coupling phenomena may be investigated. An analytical method for coupling an aeroelastically scaled model rotor system to the ARES-II is developed in the current study. Models of the testbed and the rotor system are developed in independent analyses, and an impedance-matching approach is used to couple the rotor system to the testbed. The development of the analytical models and the coupling method is examined, and individual and coupled results are presented for the testbed and rotor system. Coupled results are presented with and without applied hub motion, and system loads and displacements are examined. The results show that a closed-loop control system is necessary to achieve desired hub motions, that proper modeling requires including the loads at the rotor hub and rotor control system, and that the strain-gauge balance placed in the rotating system of the ARES-II provided the best loads results.

  14. Monitoring Eruptive Activity at Mount St. Helens with TIR Image Data

    NASA Technical Reports Server (NTRS)

    Vaughan, R. G.; Hook, S. J.; Ramsey, M. S.; Realmuto, V. J.; Schneider, D. J.

    2005-01-01

    Thermal infrared (TIR) data from the MASTER airborne imaging spectrometer were acquired over Mount St. Helens in Sept and Oct, 2004, before and after the onset of recent eruptive activity. Pre-eruption data showed no measurable increase in surface temperatures before the first phreatic eruption on Oct 1. MASTER data acquired during the initial eruptive episode on Oct 14 showed maximum temperatures of similar to approximately 330 C and TIR data acquired concurrently from a Forward Looking Infrared (FLIR) camera showed maximum temperatures similar to approximately 675 C, in narrow (approximately 1-m) fractures of molten rock on a new resurgent dome. MASTER and FLIR thermal flux calculations indicated a radiative cooling rate of approximately 714 J/m(exp 2)/s over the new dome, corresponding to a radiant power of approximately 24 MW. MASTER data indicated the new dome was dacitic in composition, and digital elevation data derived from LIDAR acquired concurrently with MASTER showed that the dome growth correlated with the areas of elevated temperatures. Low SO2 concentrations in the plume combined with sub-optimal viewing conditions prohibited quantitative measurement of plume SO2. The results demonstrate that airborne TIR data can provide information on the temperature of both the surface and plume and the composition of new lava during eruptive episodes. Given sufficient resources, the airborne instrumentation could be deployed rapidly to a newly-awakening volcano and provide a means for remote volcano monitoring.

  15. View of inside second floor stairwell of George Washington Junior ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of inside second floor stairwell of George Washington Junior High School looking at double doors, facing north. - George Washington Junior High School, 707 Columbus Drive, Tampa, Hillsborough County, FL

  16. America's Hero to the World, George C. Marshall. Teacher's Guide. Second Edition [and] Resource Packet [and] George C. Marshall: An American Leader. A Teacher's Notebook.

    ERIC Educational Resources Information Center

    Thompson, Rachel Yarnell; Sittig, Linda H.

    This teaching unit about George C. Marshall contains a teacher's guide, a resource packet, and a teacher's notebook. The teacher's guide includes ten introductory, overarching, and culminating activities: (1) About this Guide; (2) Getting to Know Him; (3) Marshal on Video; (4) Share a Space with a Hero; (5) On a Global Stage--Links; (6) A Picture…

  17. Twisting and Writhing with George Ellery Hale

    NASA Astrophysics Data System (ADS)

    Canfield, Richard C.

    2013-06-01

    Early in his productive career in astronomy, George Ellery Hale developed innovative solar instrumentation that allowed him to make narrow-band images. Among the solar phenomena he discovered were sunspot vortices, which he attributed to storms akin to cyclones in our own atmosphere. Using the concept of magnetic helicity, physicists and mathematicians describe the topology of magnetic fields, including twisting and writhing. Our contemporary understanding of Hale's vortices as a consequence of large-scale twist in sunspot magnetic fields hinges on a key property of helicity: conservation. I will describe the critical role that this property plays, when applied to twist and writhe, in a fundamental aspect of global solar magnetism: the hemispheric and solar cycle dependences of active region electric currents with respect to magnetic fields. With the advent of unbroken sequences of high-resolution magnetic images, such as those presently available from the Helioseismic and Magnetic Imager on Solar Dynamics Observatory, the flux of magnetic helicity through the photosphere can be observed quantitatively. As magnetic flux tubes buoy up through the convection zone, buffeted and shredded by turbulence, they break up into fragments by repeated random bifurcation. We track these rising flux fragments in the photosphere, and calculate the flux of energy and magnetic helicity there. Using a quantitative model of coronal currents, we also track connections between these fragments to calculate the energy and magnetic helicity stored at topological interfaces that are in some ways analogous to the storage of stress at faults in the Earth's crust. Comparison of these values to solar flares and interplanetary coronal mass ejections implies that this is the primary storage mechanism for energy and magnetic helicity released in those phenomena, and suggests a useful tool for quantitative prediction of geomagnetic storms.

  18. George Peabody's (1795-1869) Educational Legacy.

    ERIC Educational Resources Information Center

    Parker, Franklin; Parker, Betty J.

    During his career, George Peabody financially supported educational endeavors and went beyond the accumulation of money to leave for one's children. His support began in the mid-1800s and his educational legacy remains. He established: (1) a $2 million Peabody Education Fund to promote public schools and teacher training in 12 civil war devastated…

  19. Prince George's Community College Annual Assessment Report.

    ERIC Educational Resources Information Center

    Prince George's Community Coll., Largo, MD. Office of Institutional Research and Analysis.

    Prepared in response to guidelines established by the Maryland Higher Education Commission, this two-part report presents data on student learning outcomes and minority student achievement at Prince George's Community College (PGCC) in Largo, Maryland. Part 1 focuses primarily on fall 1991 entrants but includes longitudinal data where applicable.…

  20. George Lakoff's New Happiness: Politics after Rationality

    ERIC Educational Resources Information Center

    Parrott, John B.

    2009-01-01

    Berkeley professor of linguistics and cognitive science George Lakoff is among the handful of current faculty members in the United States to have successfully recast himself as a significant figure in national politics. Though his views place rather far on the progressive left, he has, unlike some other scholar-activists, focused most of his…

  1. George A. Towns Elementary School. Atlanta, Georgia

    ERIC Educational Resources Information Center

    Burt, Ralph H.

    1976-01-01

    A project testing solar heating and cooling in an existing building, the George A. Towns Elementary School, is intended to provide information on system design and performance, allow the identification and correction of problems encountered in installing large units, and gauge community/user reaction to solar equipment. (Author/MLF)

  2. George C. Reid (1929-2011)

    NASA Astrophysics Data System (ADS)

    Rosenlof, Karen H.; Crutzen, Paul J.; Fehsenfeld, Fred C.; Ennis, Christine A.

    2011-09-01

    George Colvin Reid, a pioneering solar and climate scientist, passed away at his home in Boulder, Colo., on 6 May 2011 after a brief battle with pancreatic cancer. George was 81. His legacy includes an impressive and prolific scientific career that spanned nearly 60 years. George was a world leader in atmospheric science with an exceptionally broad understanding of atmospheric phenomena encompassing both dynamics and chemistry. Early in his career, George wrote a number of influential papers with Harold Leinbach, Gordon Little, and Colin Hines on energetic particles in solar flares and the effect of such particles on the Earth's atmosphere. He and Harold Leinbach coined the often quoted phrase “polar cap absorption” and its acronym “PCA,” which have entered the lexicon of atmospheric science to describe the interaction of solar flares on the Earth's atmosphere at high latitudes. As his career progressed, his research interests expanded to include solar energetic particles, solar influences on the upper atmosphere, ion chemistry in the upper atmosphere, noctilucent clouds, the dynamics and chemistry of the middle atmosphere, the mechanisms of global climate change with emphasis on the tropics, and the influence of solar variability on the lower atmosphere and ocean temperatures.

  3. George Gamow and the Big Bang

    NASA Astrophysics Data System (ADS)

    Chernin, Artur D.

    1995-11-01

    George Gamow (1904 1968) was a man with boundless interests and imagination that took him from relativity theory to quantum mechanics and nuclear physics, back to cosmology and then to genetics. He had made seminal contributions to these key areas of modern knowledge which ensured him an enduring place among the giants of twentieth-century science.

  4. Connect the Book. George Washington's Teeth

    ERIC Educational Resources Information Center

    Brodie, Carolyn S.

    2005-01-01

    February celebrates both National Children's Dental Health Month and President's Day (February 21), so this month's "Connect the Book" column features a book with connections to both events. George Washington, the first President of the United States (1789-1797) and known as the "Father of Our Country," had a serious dental health problem that…

  5. George MacDonald's Estimate of Childhood

    ERIC Educational Resources Information Center

    Pridmore, John

    2007-01-01

    The nineteenth-century fantasy writer George MacDonald believed that "it is better to be a child in a green field than a knight of many orders." In this paper, I shall explore the bearing of this high estimate of childhood on spiritual education. MacDonald explores the spirituality of the child in his essay "A Sketch of Individual Development" and…

  6. On the Teachings of George Grant

    ERIC Educational Resources Information Center

    Pinar, William F.

    2014-01-01

    One of Canada's greatest public intellectuals, George Grant (1918-1988) studied history as an undergraduate, focusing on concepts and themes rather than minutiae. That same intellectual disposition surfaced later at Oxford, where he had gone on a Rhodes scholarship to study law. Returning to Oxford after the war, he left law to study…

  7. Teaching about George Washington. ERIC Digest.

    ERIC Educational Resources Information Center

    Vontz, Thomas S.; Nixon, William A.

    No generation in U.S. history has matched that of the founding era for its array of talented and influential political thinkers and actors. These individuals (such as George Washington, John Adams, Benjamin Franklin, Alexander Hamilton, Thomas Jefferson, and James Madison) possessed traits of character and intellect that significantly shaped the…

  8. George Washington Carver: A Most Inventive Mind.

    ERIC Educational Resources Information Center

    Davis, Marci

    1989-01-01

    Discusses the life of George Washington Carver. Explains how he achieved his goals of educating a better southern farmer and creating a better southern citizen based on his principles of agriculture economics. Discusses Carver's educational and teaching experiences that eventually lead to an expansion of human potential. (JS)

  9. 27 CFR 9.109 - Northern Neck George Washington Birthplace.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Viticultural Areas § 9.109 Northern Neck George Washington Birthplace. (a) Name. The name of the viticultural area described in this section is “Northern Neck George Washington Birthplace.” (b) Approved maps. The appropriate maps for determining the boundaries of the Northern Neck George Washington Birthplace...

  10. 27 CFR 9.109 - Northern Neck George Washington Birthplace.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Viticultural Areas § 9.109 Northern Neck George Washington Birthplace. (a) Name. The name of the viticultural area described in this section is “Northern Neck George Washington Birthplace.” (b) Approved maps. The appropriate maps for determining the boundaries of the Northern Neck George Washington Birthplace...

  11. 27 CFR 9.109 - Northern Neck George Washington Birthplace.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Viticultural Areas § 9.109 Northern Neck George Washington Birthplace. (a) Name. The name of the viticultural area described in this section is “Northern Neck George Washington Birthplace.” (b) Approved maps. The appropriate maps for determining the boundaries of the Northern Neck George Washington Birthplace...

  12. 27 CFR 9.109 - Northern Neck George Washington Birthplace.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Viticultural Areas § 9.109 Northern Neck George Washington Birthplace. (a) Name. The name of the viticultural area described in this section is “Northern Neck George Washington Birthplace.” (b) Approved maps. The appropriate maps for determining the boundaries of the Northern Neck George Washington Birthplace...

  13. 27 CFR 9.109 - Northern Neck George Washington Birthplace.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Viticultural Areas § 9.109 Northern Neck George Washington Birthplace. (a) Name. The name of the viticultural area described in this section is “Northern Neck George Washington Birthplace.” (b) Approved maps. The appropriate maps for determining the boundaries of the Northern Neck George Washington Birthplace...

  14. Re-Imagining the 21st Century School Library: From Storage Space to Active Learning Space

    ERIC Educational Resources Information Center

    Grigsby, Susan K. S.

    2015-01-01

    As libraries adjust to the needs of the 21st century, there needs to be a different way of thinking in regards to its design. School libraries have traditionally been designed as large rooms for the storage of materials for research and pleasure reading. As more and more districts focus their attention on digital acquisitions, the need for storage…

  15. 75 FR 53706 - Science and Technology (S&T) Directorate: Agency Information Collection Activities: Submission...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ..., leading to improved safety and productivity. The DHS invites interested persons to comment on the... DHS S&T to address reported capability gaps, leading to improved safety and productivity without undue... capability gaps, leading to improved safety and productivity for first responders. (4) An estimate of...

  16. Complete Genome Sequence of the Sugar Cane Endophyte Pseudomonas aurantiaca PB-St2, a Disease-Suppressive Bacterium with Antifungal Activity toward the Plant Pathogen Colletotrichum falcatum

    PubMed Central

    Bauer, Judith S.

    2014-01-01

    The endophytic bacterium Pseudomonas aurantiaca PB-St2 exhibits antifungal activity and represents a biocontrol agent to suppress red rot disease of sugar cane. Here, we report the completely sequenced 6.6-Mb genome of P. aurantiaca PB-St2. The sequence contains a repertoire of biosynthetic genes for secondary metabolites that putatively contribute to its antagonistic activity and its plant-microbe interactions. PMID:24459254

  17. Eruptive activity at Mount St Helens, Washington, USA, 1984-1988: a gas geochemistry perspective

    USGS Publications Warehouse

    McGee, K.A.; Sutton, A.J.

    1994-01-01

    The results from two different types of gas measurement, telemetered in situ monitoring of reducing gases on the dome and airborne measurements of sulfur dioxide emission rates in the plume by correlation spectrometry, suggest that the combination of these two methods is particularly effective in detecting periods of enhanced degassing that intermittently punctuate the normal background leakage of gaseous effluent from Mount St Helens to the atmosphere. Gas events were recorded before lava extrusion for each of the four dome-building episodes at Mount St Helens since mid-1984. For two of the episodes, precursory reducing gas peaks were detected, whereas during three of the episodes, COSPEC measurements recorded precursory degassing of sulfur dioxide. During one episode (October 1986), both reducing gas monitoring and SO2 emission rate measurements simultaneously detected a large gas release several hours before lava extrusion. Had both types of gas measurements been operational during each of the dome-building episodes, it is thought that both would have recorded precursory signals for all four episodes. Evidence from the data presented herein suggests that increased degassing at Mount St Helens becomes detectable when fresh upward-moving magma is between 2 km and a few hundred meters below the base of the dome and between about 60 and 12 hours before the surface extrusion of lava. ?? 1994 Springer-Verlag.

  18. Paleomagnetism of King George Island, South Shetlands, Antarctica

    NASA Astrophysics Data System (ADS)

    Slotznick, S. P.; Kirschvink, J. L.; Raub, T. D.; Swanson-Hysell, N.; Edgar, L.

    2011-12-01

    During December of 2009 when the US R/V Lawrence M. Gould was iced out of the Antarctic Peninsula, we collected core and block samples from 17 different flows and dikes at three sampling areas on Weaver Peninsula and Fildes Peninsula, King George Island, South Shetland Islands, Antarctica. Two of the three sampling areas on Weaver Peninsula and Fildes Peninsula were near dikes with Ar-Ar ages of 54.6 ± 3.8 Ma and 57.4 ± 2.1 Ma respectively, close in age to the Paleocene Eocene Thermal Maximum (PETM) (Kraus 2005, Kraus et al. 2007). After removal of significant magnetically soft components by low-temperature cycling and weak AF demagnetization, the basaltic flows from the Weaver Peninsula preserve a dual-polarity characteristic remanence isolated by higher-field AF demagnetization with an in-situ magnetization of D = 166.3, I= 65.4 (n/N = 24/30, α95 = 6.31). This direction, prior to correction for bedding tilt, is indistinct from a plausible Cenozoic reversed polarity magnetization for the site, while correcting for bedding tilt results in anomalously shallow inclinations. This result implies a post-tilting thermochemical remagnetization origin for the characteristic remanence. Analyses of the baked contact, dikes, and conglomerate tests help constrain the age of this event in context of subsequent Cenozoic magmatism on King George Island. Rock magnetic and Kappabridge experiments show that the magnetic mineralogy of the samples is often dominated by magnetite, with titanomagnetite and hematite present in some flows. The results of this multi-site study of Weaver and Fildes Peninsulas add to a growing paleomagnetic database for volcanic rocks from King George Island (Valencio et al. 1979, Kraus et al. 2010, Watts et al. 1984, Nawrocki et al. 2010) and contribute to a better understanding of the complex tectonic and magmatic activity of the South Shetland Islands.

  19. Mitochondria-associated endoplasmic reticulum membrane (MAM) regulates steroidogenic activity via steroidogenic acute regulatory protein (StAR)-voltage-dependent anion channel 2 (VDAC2) interaction.

    PubMed

    Prasad, Manoj; Kaur, Jasmeet; Pawlak, Kevin J; Bose, Mahuya; Whittal, Randy M; Bose, Himangshu S

    2015-01-30

    Steroid hormones are essential for carbohydrate metabolism, stress management, and reproduction and are synthesized from cholesterol in mitochondria of adrenal glands and gonads/ovaries. In acute stress or hormonal stimulation, steroidogenic acute regulatory protein (StAR) transports substrate cholesterol into the mitochondria for steroidogenesis by an unknown mechanism. Here, we report for the first time that StAR interacts with voltage-dependent anion channel 2 (VDAC2) at the mitochondria-associated endoplasmic reticulum membrane (MAM) prior to its translocation to the mitochondrial matrix. In the MAM, StAR interacts with mitochondrial proteins Tom22 and VDAC2. However, Tom22 knockdown by siRNA had no effect on pregnenolone synthesis. In the absence of VDAC2, StAR was expressed but not processed into the mitochondria as a mature 30-kDa protein. VDAC2 interacted with StAR via its C-terminal 20 amino acids and N-terminal amino acids 221-229, regulating the mitochondrial processing of StAR into the mature protein. In the absence of VDAC2, StAR could not enter the mitochondria or interact with MAM-associated proteins, and therefore steroidogenesis was inhibited. Furthermore, the N terminus was not essential for StAR activity, and the N-terminal deletion mutant continued to interact with VDAC2. The endoplasmic reticulum-targeting prolactin signal sequence did not affect StAR association with the MAM and thus its mitochondrial targeting. Therefore, VDAC2 controls StAR processing and activity, and MAM is thus a central location for initiating mitochondrial steroidogenesis. PMID:25505173

  20. Mitochondria-associated Endoplasmic Reticulum Membrane (MAM) Regulates Steroidogenic Activity via Steroidogenic Acute Regulatory Protein (StAR)-Voltage-dependent Anion Channel 2 (VDAC2) Interaction*

    PubMed Central

    Prasad, Manoj; Kaur, Jasmeet; Pawlak, Kevin J.; Bose, Mahuya; Whittal, Randy M.; Bose, Himangshu S.

    2015-01-01

    Steroid hormones are essential for carbohydrate metabolism, stress management, and reproduction and are synthesized from cholesterol in mitochondria of adrenal glands and gonads/ovaries. In acute stress or hormonal stimulation, steroidogenic acute regulatory protein (StAR) transports substrate cholesterol into the mitochondria for steroidogenesis by an unknown mechanism. Here, we report for the first time that StAR interacts with voltage-dependent anion channel 2 (VDAC2) at the mitochondria-associated endoplasmic reticulum membrane (MAM) prior to its translocation to the mitochondrial matrix. In the MAM, StAR interacts with mitochondrial proteins Tom22 and VDAC2. However, Tom22 knockdown by siRNA had no effect on pregnenolone synthesis. In the absence of VDAC2, StAR was expressed but not processed into the mitochondria as a mature 30-kDa protein. VDAC2 interacted with StAR via its C-terminal 20 amino acids and N-terminal amino acids 221–229, regulating the mitochondrial processing of StAR into the mature protein. In the absence of VDAC2, StAR could not enter the mitochondria or interact with MAM-associated proteins, and therefore steroidogenesis was inhibited. Furthermore, the N terminus was not essential for StAR activity, and the N-terminal deletion mutant continued to interact with VDAC2. The endoplasmic reticulum-targeting prolactin signal sequence did not affect StAR association with the MAM and thus its mitochondrial targeting. Therefore, VDAC2 controls StAR processing and activity, and MAM is thus a central location for initiating mitochondrial steroidogenesis. PMID:25505173

  1. George Huntington: the man behind the eponym.

    PubMed Central

    Durbach, N; Hayden, M R

    1993-01-01

    George Huntington first encountered patients with the disease subsequently given his name at the age of 8 while accompanying his father and grandfather on their medical rounds. In 1872, in his twenty-first year, he described this disease so accurately and succinctly that the disease was later named after him. We have explored, through contact with previously unpublished family records and documents, the personal factors which helped George Huntington to make this observation and also investigated why this remains his sole contribution to medical research. We show by documenting his precise examinations of nature that he had profound powers of observation. Furthermore his decision not to pursue medical research was based on a commitment to patient care and a belief that he could make a greater contribution through the practice of primary care medicine rather than the pursuit of research. Images PMID:8320704

  2. George Huntington: the man behind the eponym.

    PubMed

    Durbach, N; Hayden, M R

    1993-05-01

    George Huntington first encountered patients with the disease subsequently given his name at the age of 8 while accompanying his father and grandfather on their medical rounds. In 1872, in his twenty-first year, he described this disease so accurately and succinctly that the disease was later named after him. We have explored, through contact with previously unpublished family records and documents, the personal factors which helped George Huntington to make this observation and also investigated why this remains his sole contribution to medical research. We show by documenting his precise examinations of nature that he had profound powers of observation. Furthermore his decision not to pursue medical research was based on a commitment to patient care and a belief that he could make a greater contribution through the practice of primary care medicine rather than the pursuit of research. PMID:8320704

  3. Mount St. Helens Volcano Reawakens: An Overview of the First Month of Activity

    NASA Astrophysics Data System (ADS)

    Gardner, C. A.; Sisson, T.; Scott, W. E.

    2004-12-01

    Late in the evening of 22 September 2004, a shallow (< 2 km), high-frequency earthquake swarm began beneath Mount St. Helens volcano in southwest Washington. Seismicity declined and then, on the afternoon of 25 September and the following day, rapidly increased both in rate and magnitude. This prompted the U.S. Geological Survey's Cascades Volcano Observatory to issue an alert above background level for the first time since the 1980s. Over the following week, maximum earthquake magnitudes increased to M3.5 and the first steam-and-ash emission occurred on 1 October. Four additional steam-and-ash emissions occurred through 5 October; the last and largest sent an ash plume to 15,000 feet. Seismicity then dropped to low levels and changed character to more low-frequency events where it remains as of 24 October. Throughout, earthquake locations have remained shallow. By 30 September, field observers noted localized deformation on the south side of the 1980-86 lava dome and adjacent glacier, but in retrospect the deformation probably began earlier. The volume of the deforming area, or welt, grew to 5.4 million cubic meters by 4 October, grew to 11.7 million cubic meters by 13 October, and continues growing. Gas-sensing flights began on 27 September and detected only a few point sources of magmatic gas over the next several days. By 4 October, however, emission rates for carbon dioxide were large enough to be detected in the plume and by 7 October emissions rates for carbon dioxide, hydrogen sulfide and sulfur dioxide were readily measured. Since 7 October, sulfur dioxide has remained the principal sulfur gas. Forward-Looking InfraRed (FLIR) images from 1 to 10 October recorded increasing, but well below magmatic, temperatures on the northwest flank of the welt. On 11 October, temperature measurements of 500 to 600 degrees C coincided with the appearance of a lava spine on the northwest side of the welt that heralded the beginning of exogenous dome growth. Microbeam

  4. George Gabriel Stokes on Water Wave Theory

    NASA Astrophysics Data System (ADS)

    Craik, Alex D. D.

    2005-01-01

    George Gabriel Stokes died just over 100 years ago, and it has been more than 150 years since he published his great 1847 paper on water waves. The work of Stokes' precursors, which informed his early publications of 1842 50, is described in the previous volume of the Annual Review of Fluid Mechanics (Craik 2004). Here I examine Stokes' papers and letters concerning water waves.

  5. Some Reflections on George Gamow's Creative Style

    NASA Astrophysics Data System (ADS)

    Pustylnik, I. B.

    We discuss some aspects of the rich scientific legacy of George Gamow. Our analysis is based partly on Gamow's own scientific and popular books and articles, partly on reminiscences of his contemporaries. A special attention is given to G.Gamow's contribution to deciphering DNA genetic code and to the peculiarities of the "creative laboratory" of this unique figure in XXth century physics and cosmology.

  6. THE ONEIRIC AUTOBIOGRAPHY OF GEORGES PEREC.

    PubMed

    Schwartz, Henry P

    2016-01-01

    Georges Perec's book La Boutique Obscure (1973; translated into English in 2012) serves as the basis for this paper. The book is a collection of dreams that its author dreamed from May 1968 to August 1972. The present author treats these dreams as chapters in a bizarre autobiography, elaborating Perec's life through a discussion of those dreams and using them as a starting point with which to discuss his views of dream interpretation and the role of dreams in psychoanalysis. PMID:26784719

  7. Taking precautions at KSC for Hurricane Georges

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Workers put up plywood barriers on the windows of the Operations Support Building (OSB) as part of a precautionary plan in the event that Hurricane Georges threatens Central Florida. In light of the unpredictable nature of hurricanes, the decision was made to minimize risk and provide protection to KSC personnel and to the Space Shuttle national asset. The Vehicle Assembly Building is reflected (left) in the uncovered windows of the OSB.

  8. Autobiography of Sir George Biddell Airy

    NASA Astrophysics Data System (ADS)

    Airy, George Biddell; Airy, Wilfred

    2010-06-01

    Preface; 1. Personal sketch of George Biddell Airy; 2. From his birth to his taking his B.A. degree; 3. At Trinity College, Cambridge; 4. At Cambridge Observatory; 5. At Greenwich Observatory, 1836-1846; 6. At Greenwich Observatory, 1846-1856; 7. At Greenwich Observatory, 1856-1866; 8. At Greenwich Observatory, 1866-1876; 9. At Greenwich Observatory to his resignation in 1881; 10. At the White House, Greewich, to his death; Appendix: List of printed papers; Index.

  9. [Georg Groddeck--father of psychosomatic medicine].

    PubMed

    Häfner, S

    1994-01-01

    Life and work of Georg Groddeck (1866-1934), a nearly forgotten pioneer of psychosomatic medicine, are presented. Special emphasis is laid on the term "Es" and its impacts on putting forward psychoanalytic theories as well as the relationship to Sigmund Freud. The influence of Groddeck on the development of psychoanalysis and his friendship with Sándor Ferenczi are rendered prominent. Finally, the value of Groddeck's ideas for the future of psychosomatic medicine is discussed. PMID:7941786

  10. Stimulation of StAR expression by cAMP is controlled by inhibition of highly inducible SIK1 via CRTC2, a co-activator of CREB.

    PubMed

    Lee, Jinwoo; Tong, Tiegang; Takemori, Hiroshi; Jefcoate, Colin

    2015-06-15

    In mouse steroidogenic cells the activation of cholesterol metabolism is mediated by steroidogenic acute regulatory protein (StAR). Here, we visualized a coordinated regulation of StAR transcription, splicing and post-transcriptional processing, which are synchronized by salt inducible kinase (SIK1) and CREB-regulated transcription coactivator (CRTC2). To detect primary RNA (pRNA), spliced primary RNA (Sp-RNA) and mRNA in single cells, we generated probe sets by using fluorescence in situ hybridization (FISH). These methods allowed us to address the nature of StAR gene expression and to visualize protein-nucleic acid interactions through direct detection. We show that SIK1 represses StAR expression in Y1 adrenal and MA10 testis cells through inhibition of processing mediated by CRTC2. Digital image analysis matches qPCR analyses of the total cell culture. Evidence is presented for spatially separate accumulation of StAR pRNA and Sp-RNA at the gene loci in the nucleus. These findings establish that cAMP, SIK and CRTC mediate StAR expression through activation of individual StAR gene loci. PMID:25662274

  11. George A. Kolstad (1919-1996)

    NASA Astrophysics Data System (ADS)

    Luth, W.; Heiken, G.; Weill, D.; Wang, H.; Gilbert, C.; Mitterer, R.; Duba, A.; Goldstein, N.

    George A. Kolstad, creator and leader of the U.S. Department of Energy's Geosciences Research Program, died of an aneurysm August 7, 1996, in Baltimore, Md. He is survived by Chris, his wife of 52 years, three children, Martha Rae Kolstad Wilhelm of Grinnell, Iowa, Charles D. Kolstad of Santa Barbara, Calif., and Peter K. Kolstad, of Los Angeles, Calif., and four grandchildren. George is also survived by three brothers and a sister.George was born in Elmira, N.Y., on December 10, 1919. Following high school graduation in 1937, he worked at Eastman Kodak while enrolled in night courses at the Rochester Institute of Technology and the University of Rochester. He entered Bates College in 1939 and completed his B.S. in physics and mathematics in 1943. During World War II, he worked on piezo-electricity, radar countermeasures, and information flow from radar systems in combat environments. Following his Ph.D. in physics at Yale and brief service on the faculty there, he joined the Atomic Energy Commission in 1950. He began a career of fostering and nurturing basic research efforts, first in physics and mathematics, and then in the geosciences. He was a guest staff member at the Institute for Theoretical Physics, Copenhagen, in 1956-1957, and served as a trustee of Bates College from 1958 to 1964.

  12. Nobel prize: 3 named for medicine, physiology award (George Wald, Ragnar Granit and Haldan Keffer Hartline).

    PubMed

    Dolwing, J E; Ratliff, F

    1967-10-27

    Three scientists, George Wald, Ragnar Granit, and Haldan Keffer Hartline, were named last week to share the 1967 Nobel prize in medicine or physiology. Wald is professor of biology at Harvard University. Granit is retired director of the Neurophysiological Institute of the Royal Medical School in Stockholm; at present he is serving as a visiting professor at St. Catherine's College in Oxford. Hartline is professor of biophysics at Rockefeller University. The following are appreciations and descriptions of Wald's work by John E. Dowling and of Granit's and Hartline's work by Floyd Ratliff. PMID:4860394

  13. George S. Schuyer's "Black No More"--The Black Conservative's Socialist Past.

    ERIC Educational Resources Information Center

    Diedrich, Maria

    1988-01-01

    George S. Schuyler, an outspoken reactionary conservative from the 1940s until his death in 1977, was an active member of the Socialist Party of America in the 1920s and 1930s. Examination of his novel, "Black No More" (1931) demonstrates his early Marxist leanings. (BJV)

  14. Eocene paleosols of King George Island, Maritime Antarctica

    NASA Astrophysics Data System (ADS)

    Spinola, Diogo; Portes, Raquel; Schaefer, Carlos; Kühn, Peter

    2016-04-01

    Red layers between lava flows on King George Island, Maritime Antarctica, were formed during the Eocene, which was one of the warmest periods on Earth in the Cenozoic. Our hypothesis is that these red layers are paleosols formed in periods of little or no volcanic activity. Therefore, our main objective was to identify the main pedogenic properties and features to distinguish these from diagenetic features formed after the lava emplacement. Additionally, we compared our results with volcanic soils formed under different climates to find the best present analogue. The macromorphological features indicate a pedogenic origin, because of the occurrence of well-defined horizons based on colour and structure. Micromorphological analyses showed that most important pedogenic features are the presence of biological channels, plant residues, anisotropic b-fabric, neoformed and illuvial clay and distinct soil microstructure. Although the paleosols are not strongly weathered, the geochemical data also support the pedogenic origin despite of diagenetic features as the partial induration of the profiles and zeolites filling nearly all voids in the horizons in contact with the overlying lava flow, indicating circulation of hydrothermal fluids. The macromorphological and micromorphological features of these paleosols are similar to the soils formed under seasonal climates. Thus, these paleosol features do not correspond to the other proxies (e.g. sediment, plant fossils), which indicate a wet, non-seasonal climate, as in Valdivian Forest, Chile, during the Eocene in King George Island

  15. EDITORIAL: George W Series Memorial Essays

    NASA Astrophysics Data System (ADS)

    Dodd, J. N.

    1997-01-01

    I would like to recall my experiences when I joined George Series when on study leave from the University of Otago in 1959. Like George, we had decided, some years previously, to pursue the line of research opened up by the double-resonance experiment of Brossel and Bitter. Up to that time both groups had been applying the new technique to traditional spectroscopic problems, those of measuring the fine structure, hyperhe structure, g-factors and nuclear moments. But here, in Oxford, was something new and exciting - experiments that studied the nature of light itself, questioning some long-held views. George had come to the view that, in a double-resonance experiment, one could demonstrate the inner coherence that could exist between superposition states of an atom. He, and his students Wilf Fox and Mike Taylor, had already obtained promising evidence; but he needed more definite results if he was going to allay the doubts and suspicions of some others in the Clarendon. At the time, people generally thought that light, being a superposition of radiations from many atoms with no obvious phase relation to each other, was an incoherent wave phenomenon. One could observe small scale coherence (for example, in the Young interference experiment) but it would be largely concealed by the incoherent nature of the radiation from many atoms in a source. In the experiments that had been performed the coherence was introduced between a pair of excited states (Zeeman sub-states) by the application of an oscillating magnetic field - was it not likely, according to the doubters, that the modulation observed in the fluorescence was due to "pick-up" in the amplifiers from the source of oscillations? George had to prove that this was not the cause. I well remember him saying at the time "I have a hunch that I am correct". That typified his approach to physics. The work of 1959 demonstrated beyond all doubt that substantial coherence, manifested as strong beats in the intensity of the

  16. An Institutional Autopsy of St. Augustine Junior College

    ERIC Educational Resources Information Center

    Lumadue, Richard T.

    2009-01-01

    Institutional autopsies can teach much about why learning centers fail the test of time. St. Augustine Junior College in north Florida, the brainchild of Dr. George Apel, was begun in 1942 and ended seven years later in 1949. The purposes of the short-lived college are identified for discussion in this paper. Also identified are the reasons for…

  17. Case Study of Severe Lightning Activity Prior to and During the Outbreak of the June 1st Greenbelt Tornado

    NASA Astrophysics Data System (ADS)

    Barnum, B. H.; Badesha, S.; Shishineh, A.; Adams, N. H.

    2012-12-01

    Surges in lightning activity have been known to be associated with the outbreak of tornado activity. We present a case study of a tornado that touched down near Greenbelt Maryland during the evening of June 1st 2012. Preceding the tornado touchdown, two single point lightning detection systems, a Boltek LD-250 and Vaisala SA20, recorded very high lightning activity rates. An electric field mill (EFM) was also making measurements and recorded large, rapid amplitude oscillations in the vertical electric fields. These electric field oscillations quickly subsided after the initial tornado touchdown. The lightning activity also generated significant RF interference in the S-band dish antenna operated at the Applied Physics Laboratory. It was somewhat surprising that the lightning activity produced enough radiation at these frequencies to cause measured levels of interference which could potentially impair satellite communications. Our interpretation of the EFM data is that intensive vertical forcing and rotation in the thunderstorm during the tornado formation caused the observed rapid electric field oscillations. At the same time, the vertical mixing in the storm caused a surge in lightning activity rates recorded by the Boltek and Vaisala sensors. Following the tornado touchdown, there was a rapid decrease in the lightning rates from the sensors. The EFM oscillations also abruptly ceased and went to a more normal slow-varying pattern typically observed during other thunderstorms without associated tornado activity. It is suggested that a network of field mills could provide realtime warning of imminent tornado activity.

  18. TESTING PHARMACEUTICAL RELEASE OF ACTIVE SUBSTANCES FROM MEDICINAL PRODUCTS CONTAINING ST. JOHN'S WORT.

    PubMed

    Sakowska, Joanna; Anyzewska, Małgorzata; Łozak, Anna; Kowalczuk, Anna; Jabłczyńska, Renata

    2016-01-01

    The aim of this study was to determine the content of hypericins and flavonoids in tablets and capsules containing the extract or powdered herb of St. John's wort, in herbs for infusion and herbal infusions and to release of these compounds from tablets and capsules. HPLC method was used to determine the assay of hypericins and flavonoids in all tested products. The hypericins content was between 0.35 mg and 1.44 mg per tablet or capsule. The release of hypericins from these products in the phosphate buffer of pH 6.8 is between 30 and 60% of the determined content. The degree of hypericins release from herbs into infusions was 15% on average, which corresponds to 0.64 mg of hypericins per infusion of 4 g of herbs. The flavonoids content was between 8.79 and 36.3 mg per tablet or capsule. The release of flavonoids in the phosphate buffer of pH 6.8 is between 63 and 85% of the determined content. The degree of flavonoids release was 76% on average, which corresponds to 77.0 mg per infusion of 4 g of herbs. The test results confirmed that infusions from the St. John's wort constitute are a rich source of flavonoids. At the same time, the universally accepted opinion that aqueous infusions contain only trace amounts of hypericins was not confirmed. Infusions from Herba hyperici may also be a source of hypericins in amounts comparable with the minimum dose recommended for the treatment of mild to moderate depressive episodes. PMID:27180432

  19. Absent Aortic Valve in DiGeorge Syndrome.

    PubMed

    Bertsch, Elizabeth C; Minturn, Lucy; Gotteiner, Nina L; Ernst, Linda M

    2016-01-01

    A 20-week-old fetus with the 22q11.2 deletion characteristic of DiGeorge syndrome is described with vertebral segmentation abnormalities and complex cardiovascular anomalies including an absent aortic valve. This is only the second known case of absent aortic valve in association with DiGeorge syndrome. We discuss the association of absent aortic valve with other conotruncal defects and the utility of fetal echocardiography in the diagnosis of DiGeorge syndrome. PMID:26230226

  20. Lead acetate does not inhibit dimethylnitrosamine activation and interacts with phenobarbital which is genotoxic in the ST cross of the Drosophila wing spot test.

    PubMed

    Castañeda-Partida, Laura; Heres-Pulido, Ma Eugenia; Guzmán-Rincón, Judith; Hernández-Portilla, Luis Barbo; Dueñas-García, Irma Elena; Durán-Díaz, Angel; Delfín-Alcalá, Irma

    2011-09-01

    Lead acetate (PbAc) is known to inhibit the synthesis of the heme group, needed for hemeproteins like Cytochromes P450 (CYP450s). Dimethylnitrosamine (DMN) requires metabolic activation by CYP450s. The Drosophila wing spot test was performed to establish whether PbAc inhibits DMN activation in the standard (ST) and high bioactivation (HB) crosses, with different levels of CYP450s. Phenobarbital (PH) was used as an antagonist for its ability to induce CYP450s synthesis. PbAc (0.01, 0.1, 1.0mM) produced significant small spots frequencies in the ST cross, indicating a possible genotoxic activity, however, the total spots frequency was negative at all concentrations. DMN (0.076 mM) was genotoxic in both crosses; surprisingly, PH (12 mM) was genotoxic and the PH-DMN treatment resulted synergic in the ST cross. Interestingly, the PbAc-PH pre-co-treatments showed a possible interaction in the ST cross. The GC-MS analysis showed a drop in the PH content as the PbAc concentration increased. PbAc also seemed to inhibit the genotoxic activity of PH, except at 0.01 mM. It is concluded that PbAc does not inhibit DMN activation by CYP450s in both crosses since it exerted a clear genotoxicity and that PH is genotoxic and interacts with PbAc in the ST but not the HB cross. PMID:21672598

  1. 5. Historic American Buildings Survey George F. Neuschafer, Photographer October ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Historic American Buildings Survey George F. Neuschafer, Photographer October 16, 1941 EXTERIOR - SOUTHEAST CORNER DETAIL (see cornerstone inscribed Built 1759.) - Israel Swayze House, Hope, Warren County, NJ

  2. 6. Historic American Buildings Survey, George J. Vaillancourt, Photographer, 1932 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey, George J. Vaillancourt, Photographer, 1932 TRIPLE WINDOW IN SECOND STORY. - Vaucluse, Wapping Road (Parts in Metropolitan Museum, NY), Middletown, Newport County, RI

  3. 11. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 STAIRS FROM K STREET ENTRANCE - Capital Traction Company Powerhouse, 3142 K Street Northwest, Washington, District of Columbia, DC

  4. 11. HISTORIC AMERICAN BUILDINGS SURVEY George Neuschafer, photographer. INTERIOR: BAKE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. HISTORIC AMERICAN BUILDINGS SURVEY George Neuschafer, photographer. INTERIOR: BAKE OVEN IN CELLAR FIREPLACE IN FIRST ADDITION - American House Hotel, Union Street & Moravian Alley, Hope, Warren County, NJ

  5. 1. Historic American Buildings Survey George M. Cushing, Photographer October ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey George M. Cushing, Photographer October 1967 GENERAL EXTERIOR VIEW, LOOKING NORTHEAST - Guyot-Horsford House & Stable, 27 Craigie Street, Cambridge, Middlesex County, MA

  6. 10. Historic American Buildings Survey, George A. Eisenman, Photographer September, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Historic American Buildings Survey, George A. Eisenman, Photographer September, 1964 TYPICAL HANDRAIL, THIRD FLOOR. - Harrison Building, 4 South Fifteenth Street, Philadelphia, Philadelphia County, PA

  7. 8. Historic American Buildings Survey, George A. Eisenman, Photographer September, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Historic American Buildings Survey, George A. Eisenman, Photographer September, 1964 THIRD FLOOR CORRIDOR FROM SOUTH. - Harrison Building, 4 South Fifteenth Street, Philadelphia, Philadelphia County, PA

  8. 9. Historic American Buildings Survey, George A. Eisenman, Photographer September, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Historic American Buildings Survey, George A. Eisenman, Photographer September, 1964 SOUTHEAST CORNER OFFICE, THIRD FLOOR. - Harrison Building, 4 South Fifteenth Street, Philadelphia, Philadelphia County, PA

  9. 2. Historic American Buildings Survey, George A. Eisenman, Photographer April, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey, George A. Eisenman, Photographer April, 1961 SOUTHWEST (FRONT) AND SOUTHEAST ELEVATIONS. - Shoomac Park, Ridge Avenue & Wissahickon Drive, Philadelphia, Philadelphia County, PA

  10. 1. Historic American Buildings Survey, George J. Vaillancourt, Photographer, 1938, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey, George J. Vaillancourt, Photographer, 1938, from a film by unknown, VIEW OF ORIGINAL ROOF TRUSSES. - Market House, Market Square, Providence, Providence County, RI

  11. 3. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 SOUTH SIDE FROM POTOMAC RIVER - Capital Traction Company Powerhouse, 3142 K Street Northwest, Washington, District of Columbia, DC

  12. iMUSH: The design of the Mount St. Helens high-resolution active source seismic experiment

    NASA Astrophysics Data System (ADS)

    Kiser, Eric; Levander, Alan; Harder, Steve; Abers, Geoff; Creager, Ken; Vidale, John; Moran, Seth; Malone, Steve

    2013-04-01

    Mount St. Helens is one of the most societally relevant and geologically interesting volcanoes in the United States. Although much has been learned about the shallow structure of this volcano since its eruption in 1980, important questions still remain regarding its magmatic system and connectivity to the rest of the Cascadia arc. For example, the structure of the magma plumbing system below the shallowest magma chamber under the volcano is still only poorly known. This information will be useful for hazard assessment for the southwest Washington area, and also for gaining insight into fundamental scientific questions such as the assimilation and differentiation processes that lead to the formation of continental crust. As part of the multi-disciplinary imaging of Magma Under St. Helens (iMUSH) experiment, funded by NSF GeoPRISMS and EarthScope, an active source seismic experiment will be conducted in late summer 2014. The experiment will utilize all of the 2600 IRIS/PASSCAL/USArray Texan instruments. The instruments will be deployed as two 1000-instrument consecutive refraction profiles (one N/S and one WNW/ESE). Each of these profiles will be accompanied by two 1600-instrument areal arrays at varying distances from Mount St. Helens. Finally, one 2600-instrument areal array will be centered on Mount St. Helens. These instruments will record a total of twenty-four 500-1000 kg shots. Each refraction profile will have an average station spacing of 150 m, and a total length of 150 km. The stations in the areal arrays will be separated by ~1 km. A critical step in the success of this project is to develop an experimental setup that can resolve the most interesting aspects of the magmatic system. In particular, we want to determine the distribution of shot locations that will provide good coverage throughout the entire model space, while still allowing us to focus on regions likely to contain the magmatic plumbing system. In this study, we approach this problem by

  13. York, Alcuin, and Sir George Newman

    PubMed Central

    WALKER-SMITH, J

    2001-01-01

    The history of medicine can give insights into past achievements and provide knowledge and even inspiration, a valuable commodity for young students and all doctors. The contribution of Alcuin of York to basic education, and its appreciation by Sir George Newman, medical officer of health and first Chief Medical Officer of the UK in 1919, is recalled. Newman's Quaker education at Bootham School, his views on the main principles of such an education, as well as his influence on its establishment are summarised. A liberal education for doctors is important and knowledge and inspiration from the past may be one factor in enhancing morale.

 PMID:11668116

  14. George Eliot's interrogation of physiological future knowledge.

    PubMed

    Claggett, Shalyn

    2011-01-01

    This essay tracks George Eliot's sustained interest in the epistemological problems surrounding the Victorian tendency to envision the future through the body's materiality. It argues that her nuanced criticism of phrenology in "The Lifted Veil" (1859) and "A Minor Prophet" (1865) addresses the delimiting psychological and social effects that attend an applied theory of physiological determinism. Returning to this problem in Daniel Deronda (1876), Eliot offers Mordecai's plan to posit Deronda's body as a living emblem as a radical alternative to racial iconography and typological meaning—a move that allowed her to reconcile the body's legibility with a future beyond socially inscribed possibilities. PMID:22213892

  15. Promoting 21st-Century Skills in the Science Classroom by Adapting Cookbook Lab Activities: The Case of DNA Extraction of Wheat Germ

    ERIC Educational Resources Information Center

    Alozie, Nonye M.; Grueber, David J.; Dereski, Mary O.

    2012-01-01

    How can science instruction engage students in 21st-century skills and inquiry-based learning, even when doing simple labs in the classroom? We collaborated with teachers in professional development workshops to transform "cookbook" activities into engaging laboratory experiences. We show how to change the common classroom activity of DNA…

  16. Hot spot activity and tectonic settings near Amsterdam-St. Paul plateau (Indian Ocean)

    NASA Astrophysics Data System (ADS)

    Janin, M.; HéMond, C.; Guillou, H.; Maia, M.; Johnson, K. T. M.; Bollinger, C.; Liorzou, C.; Mudholkar, A.

    2011-05-01

    The Amsterdam-St. Paul (ASP) plateau is located in the central part of the Indian Ocean and results from the interaction between the ASP hot spot and the Southeast Indian Ridge (SEIR). It is located near the diffuse boundary between the Capricorn and Australian plates. The seamount chain of the Dead Poets (CDP) is northeast of the ASP plateau and may represent older volcanism related to the ASP hot spot; this chain consists of two groups of seamounts: (1) large flat-topped seamounts formed 8-10 Ma and (2) smaller conical seamounts formed during the last 2 Myr. The ASP hot spot has produced two pulses of magmatism that have been ponded under the ASP plateau and erupted along the divergent boundary between the Capricorn and Australian plates. The N65° orientation of the CDP as well as the seamount's elongated shapes support an opening motion between the Capricorn and Australian plates along a suture oriented in the N155° direction. This motion compared to the Antarctic plate amounts to an apparent velocity of 7.7 cm/yr northeastward for the Capricorn-Australian block. This motion does not fit with a fixed plume model. We suggest, therefore, that the ASP plume experienced a motion of about 1-2 cm/yr to the SW, which is opposite to the asthenospheric flow in this region and suggests a deep-seated plume.

  17. Critical role of evolutionarily conserved glycosylation at Asn211 in the intracellular trafficking and activity of sialyltransferase ST3Gal-II.

    PubMed

    Ruggiero, Fernando M; Vilcaes, Aldo A; Iglesias-Bartolomé, Ramiro; Daniotti, José L

    2015-07-01

    ST3Gal-II, a type II transmembrane protein, is the main mammalian sialyltransferase responsible for GD1a and GT1b ganglioside biosynthesis in brain. It contains two putative N-glycosylation sites (Asn(92) and Asn(211)). Whereas Asn(92) is only conserved in mammalian species, Asn(211) is highly conserved in mammals, birds and fish. The present study explores the occupancy and relevance for intracellular trafficking and enzyme activity of these potential N-glycosylations in human ST3Gal-II. We found that ST3Gal-II distributes along the Golgi complex, mainly in proximal compartments. By pharmacological, biochemical and site-directed mutagenesis, we observed that ST3Gal-II is mostly N-glycosylated at Asn(211) and that this co-translational modification is critical for its exit from the endoplasmic reticulum and proper Golgi localization. The individual N-glycosylation sites had different effects on ST3Gal-II enzymatic activity. Whereas the N-glycan at position Asn(211) seems to negatively influence the activity of the enzyme using both glycolipid and glycoprotein as acceptor substrates, the single N-glycan mutant at Asn(92) had only a moderate effect. Lastly, we demonstrated that the N-terminal ST3Gal-II domain containing the cytosolic, transmembrane and stem region (amino acids 1-51) is able to drive a protein reporter out of the endoplasmic reticulum and to retain it in the Golgi complex. This suggests that the C-terminal domain of ST3Gal-II depends on N-glycosylation to attain an optimum conformation for proper exit from the endoplasmic reticulum, but it does not represent an absolute requirement for Golgi complex retention of the enzyme. PMID:25916169

  18. Ecosystem management: A comparison of greater yellowstone and georges bank

    NASA Astrophysics Data System (ADS)

    Burroughs, Richard H.; Clark, Tim W.

    1995-09-01

    Ecosystem management links human activities with the functioning of natural environments over large spatial and temporal scales. Our examination of Greater Yellowstone and Georges Bank shows similarities exist between human uses, administrative characteristics, and some biophysical features. Each region faces growing pressures to replace traditional extractive uses with more sustainable extractive or noncommodity uses coupled with concern about endangered species. Ecosystem management as a set of practical guidelines for making decisions under evolving expectations is far from complete, and it embodies new demands on individuals and institutions. In each system these challenges are considered relative to: the public's symbolic understanding of the management challenge, ecosystem management ambiguities, information availability, information use, administrative setting, and learning capabilities of governance organizations Progress in making ecosystem management operational may occur as refinements in content and approach make it an increasingly attractive option for resource users, the public, and government officials.

  19. 75 FR 23798 - Boundary Revision at George Washington Carver National Monument

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-04

    ... National Park Service Boundary Revision at George Washington Carver National Monument AGENCY: National Park... the boundary of George Washington Carver National Monument, Newton County, Missouri, to include..., Superintendent, George Washington Carver National Monument, 5646 Carver Road, Diamond, Missouri 64840, or...

  20. Effect of the acupoints ST-36 (Zusanli) and SP-6 (Sanyinjiao) on intestinal myoelectric activity of Wistar rats.

    PubMed

    Tabosa, A; Yamamura, Y; Forno, E R; Mello, L E A M

    2002-06-01

    Despite its ancient use as a therapeutic tool to treat several ailments, acupuncture still faces the challenge of scrutiny by Western science both in terms of its efficacy and in terms of the characterization of its effects and mechanisms of actions underlying these effects. We investigated under well-controlled and carefully characterized conditions the influence of electrical stimulation of acupuncture points ST-36 (Zusanli) and SP-6 (Sanyinjiao) on the myoelectric activity of the small intestine of 38 adult male Wistar rats. Electrical recordings obtained by means of four electrodes chronically implanted in the small intestine were used to assess the effects of acupuncture (electroacupuncture stimulation set at 2 Hz, intermittent stimulation, 1 V, for 30 min). Immobilization of the animals was associated with a consistent decrease (-8 +/- 7%) in the myoelectric activity of the small intestine as measured by means of the root mean square. Conversely, acupuncture was able to significantly increase (overshoot) this activity compared to baseline (+44 +/- 7%). In contrast, immobilized animals subjected to sham acupuncture had only modest (nonsignificant) increases in myoelectric activity (+9 +/- 6%). Using carefully controlled conditions we confirmed previous noncontrolled studies on the ability of acupuncture to alter intestinal motility. The characterization of the topographic and temporal profiles of the effects observed here represents a basis for future dissection of the physiological and pharmacological systems underlying these effects. PMID:12045840

  1. Our Western Heritage: An Interview with Robert George

    ERIC Educational Resources Information Center

    Iannone, Carol

    2012-01-01

    This article presents an interview with Robert George, who holds Princeton's celebrated McCormick Chair in Jurisprudence and is the founding director of the James Madison Program. George has served on the President's Council on Bioethics and as a presidential appointee to the United States Commission on Civil Rights. He is also a member of the…

  2. Edutopian Vision: George Lucas Reimagines the American Classroom

    ERIC Educational Resources Information Center

    Pondiscio, Robert

    2010-01-01

    In this article, the author features the George Lucas Education Foundation (GLEF) and its Edutopia initiatives. The George Lucas Educational Foundation, the 19-year-old organization that runs Edutopia, has given itself a mission to "spread the word about ideal, interactive learning environments and enable others to adapt these successes locally."…

  3. "The George Lopez Show": The Same Old Hispano?

    ERIC Educational Resources Information Center

    Markert, John

    2007-01-01

    "The George Lopez Show" is the first successful television show with a Latino in a leading role that features Hispanic material since Freddie Prinze's thirty-year-old sitcom, "Chico and the Man." This study seeks to assess how Latinos are presented on "The George Lopez Show." A content analysis reveals that the show perpetuates some of the…

  4. The flavonoid content and antiproliferative, hypoglycaemic, anti-inflammatory and free radical scavenging activities of Annona dioica St. Hill

    PubMed Central

    2013-01-01

    Background Annona dioica St. Hill (Annonacaeae) is a Brazilian plant used in folk medicine for the treatment of several types of rheumatisms and diarrhoea. The focus of this work was to evaluate the in vitro antiproliferative and antioxidant activity and the in vivo hypoglycaemic and anti-inflammatory activity of A. dioica and identify the principal constituents of this plant. Methods The crude methanol extract (EAD) and hexane (HF), chloroform (CF), ethyl acetate (EAF) and hydromethanol fractions (HMF) were evaluated for free radical scavenging activity using the DPPH assay. The EAD and EAF were assayed for hypoglycaemic activity in rats. The EAD was tested in an antiproliferation assay and for anti-inflammatory effects in paw oedema, in addition to myeloperoxidase activity induced by carrageenan (Cg) in mice. The EAF was assayed using chromatographic methods. Results The fractionation of the EAF through chromatographic methods identified derivatives of the flavonoids quercetin and kaempferol. Among all the tested fractions, the ethyl acetate and hydromethanol fractions were the most potent, exhibiting an IC50 of 8.53 and 10.57 μg/mL, respectively, which is comparable to that of the commercial antioxidant butylated hydroxytoluene (BHT). The oral administration of the EAD (100 mg/kg) and EAF (15 mg/kg) inhibited the increase of glucose levels, resulting in a hypoglycaemic effect. The EAD (30 to 300 mg/kg) exhibited an anti-oedematogenic effect in Cg-induced paw oedema in a time- and dose-dependent manner. The results showed a reduction of MPO activity by A. dioica 6 h after the induction of paw oedema at all doses tested with maximal inhibition at 300 mg/kg. Conclusions Our results reveal for the first time that compounds contained in the A. dioica leaves exert anti-inflammatory, hypoglycaemic, antiproliferative, and antioxidant effects. The antioxidant activity may be associated with the presence of flavonoids. PMID:23311341

  5. Interoperability Trends in Extravehicular Activity (EVA) Space Operations for the 21st Century

    NASA Technical Reports Server (NTRS)

    Miller, Gerald E.

    1999-01-01

    No other space operations in the 21 st century more comprehensively embody the challenges and dependencies of interoperability than EVA. This discipline is already functioning at an W1paralleled level of interagency, inter-organizational and international cooperation. This trend will only increase as space programs endeavor to expand in the face of shrinking budgets. Among the topics examined in this paper are hardware-oriented issues. Differences in design standards among various space participants dictate differences in the EVA tools that must be manufactured, flown and maintained on-orbit. Presently only two types of functional space suits exist in the world. However, three versions of functional airlocks are in operation. Of the three airlocks, only the International Space Station (ISS) Joint Airlock can accommodate both types of suits. Due to functional differences in the suits, completely different operating protocols are required for each. Should additional space suit or airlock designs become available, the complexity will increase. The lessons learned as a result of designing and operating within such a system are explored. This paper also examines the non-hardware challenges presented by interoperability for a discipline that is as uniquely dependent upon the individual as EVA. Operation of space suits (essentially single-person spacecrafts) by persons whose native language is not that of the suits' designers is explored. The intricacies of shared mission planning, shared control and shared execution of joint EVA's are explained. For example, once ISS is fully functional, the potential exists for two crewmembers of different nationality to be wearing suits manufactured and controlled by a third nation, while operating within an airlock manufactured and controlled by a fourth nation, in an effort to perform tasks upon hardware belonging to a fifth nation. Everything from training issues, to procedures development and writing, to real-time operations is

  6. Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdhQ111 Model of HD

    PubMed Central

    Bowles, Kathryn R.; Brooks, Simon P.; Dunnett, Stephen B.; Jones, Lesley

    2015-01-01

    Huntington’s disease is a neurodegenerative disorder characterised primarily by motor abnormalities, and is caused by an expanded polyglutamine repeat in the huntingtin protein. Huntingtin dynamically shuttles between subcellular compartments, and the mutant huntingtin protein is mislocalised to cell nuclei, where it may interfere with nuclear functions, such as transcription. However, the mechanism by which mislocalisation of mutant huntingtin occurs is currently unknown. An immortalised embryonic striatal cell model of HD (StHdhQ111) was stimulated with epidermal growth factor in order to determine whether the subcellular localisation of huntingtin is dependent on kinase signalling pathway activation. Aberrant phosphorylation of AKT and MEK signalling pathways was identified in cells carrying mutant huntingtin. Activity within these pathways was found to contribute to the regulation of huntingtin and mutant huntingtin localisation, as well as to the expression of immediate-early genes. We propose that altered kinase signalling is a phenotype of Huntington’s disease that occurs prior to cell death; specifically, that altered kinase signalling may influence huntingtin localisation, which in turn may impact upon nuclear processes such as transcriptional regulation. Aiming to restore the balance of activity between kinase signalling networks may therefore prove to be an effective approach to delaying Huntington’s disease symptom development and progression. PMID:26660732

  7. Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdhQ111 Model of HD.

    PubMed

    Bowles, Kathryn R; Brooks, Simon P; Dunnett, Stephen B; Jones, Lesley

    2015-01-01

    Huntington's disease is a neurodegenerative disorder characterised primarily by motor abnormalities, and is caused by an expanded polyglutamine repeat in the huntingtin protein. Huntingtin dynamically shuttles between subcellular compartments, and the mutant huntingtin protein is mislocalised to cell nuclei, where it may interfere with nuclear functions, such as transcription. However, the mechanism by which mislocalisation of mutant huntingtin occurs is currently unknown. An immortalised embryonic striatal cell model of HD (StHdhQ111) was stimulated with epidermal growth factor in order to determine whether the subcellular localisation of huntingtin is dependent on kinase signalling pathway activation. Aberrant phosphorylation of AKT and MEK signalling pathways was identified in cells carrying mutant huntingtin. Activity within these pathways was found to contribute to the regulation of huntingtin and mutant huntingtin localisation, as well as to the expression of immediate-early genes. We propose that altered kinase signalling is a phenotype of Huntington's disease that occurs prior to cell death; specifically, that altered kinase signalling may influence huntingtin localisation, which in turn may impact upon nuclear processes such as transcriptional regulation. Aiming to restore the balance of activity between kinase signalling networks may therefore prove to be an effective approach to delaying Huntington's disease symptom development and progression. PMID:26660732

  8. Aurora Activities Observed by SNPP VIIRS Day-Night Band during St. Patrick's Day, 2015 G4 Level Geomagnetic Storm

    NASA Astrophysics Data System (ADS)

    Liu, T. C.; Shao, X.; Cao, C.; Zhang, B.; Fung, S. F.; Sharma, S.

    2015-12-01

    A G4 level (severe) geomagnetic storm occurred on March 17 (St. Patrick's Day), 2015 and it is among the strongest geomagnetic storms of the current solar cycle (Solar Cycle 24). The storm is identified as due to the Coronal Mass Ejections (CMEs) which erupted on March 15 from Region 2297 of solar surface. During this event, the geomagnetic storm index Dst reached -223 nT and the geomagnetic aurora electrojet (AE) index increased and reached as high as >2200 nT with large amplitude fluctuations. Aurora occurred in both hemispheres. Ground auroral sightings were reported from Michigan to Alaska and as far south as southern Colorado. The Day Night Band (DNB) of the Visible Infrared Imaging Radiometer Suite (VIIRS) onboard Suomi-NPP represents a major advancement in night time imaging capabilities. The DNB senses radiance that can span 7 orders of magnitude in one panchromatic (0.5-0.9 μm) reflective solar band and provides imagery of clouds and other Earth features over illumination levels ranging from full sunlight to quarter moon. In this paper, DNB observations of aurora activities during the St. Patrick's Day geomagnetic storm are analyzed. Aurora are observed to evolve with salient features by DNB for orbital pass on the night side (~local time 1:30am) in both hemispheres. The radiance data from DNB observation are collected at the night sides of southern and northern hemispheres and geo-located onto geomagnetic local time (MLT) coordinates. Regions of aurora during each orbital pass are identified through image processing by contouring radiance values and excluding regions with stray light near day-night terminator. The evolution of aurora are characterized with time series of the poleward and low latitude boundary of aurora, their latitude-span and area, peak radiance and total light emission of the aurora region in DNB observation. These characteristic parameters are correlated with solar wind and geomagnetic index parameters.

  9. (222)Rn activity in groundwater of the St. Lawrence Lowlands, Quebec, eastern Canada: relation with local geology and health hazard.

    PubMed

    Pinti, Daniele L; Retailleau, Sophie; Barnetche, Diogo; Moreira, Floriane; Moritz, Anja M; Larocque, Marie; Gélinas, Yves; Lefebvre, René; Hélie, Jean-François; Valadez, Arisai

    2014-10-01

    One hundred ninety-eight groundwater wells were sampled to measure the (222)Rn activity in the region between Montreal and Quebec City, eastern Canada. The aim of this study was to relate the spatial distribution of (222)Rn activity to the geology and the hydrogeology of the study area and to estimate the potential health risks associated with (222)Rn in the most populated area of the Province of Quebec. Most of the groundwater samples show low (222)Rn activities with a median value of 8.6 Bq/L. Ninety percent of samples show (222)Rn activity lower than 100 Bq/L, the exposure limit in groundwater recommended by the World Health Organization. A few higher (222)Rn activities (up to 310 Bq/L) have been measured in wells from the Appalachian Mountains and from the magmatic intrusion of Mont-Saint-Hilaire, known for its high level of indoor radon. The spatial distribution of (222)Rn activity seems to be related mainly to lithology differences between U-richer metasediments of the Appalachian Mountains and magmatic intrusions and the carbonaceous silty shales of the St. Lawrence Platform. Radon is slightly enriched in sodium-chlorine waters that evolved at contact with clay-rich formations. (226)Ra, the parent element of (222)Rn could be easily adsorbed on clays, creating a favorable environment for the production and release of (222)Rn into groundwater. The contribution of groundwater radon to indoor radon or by ingestion is minimal except for specific areas near Mont-Saint-Hilaire or in the Appalachian Mountains where this contribution could reach 45% of the total radioactive annual dose. PMID:24973780

  10. 33 CFR 334.760 - Naval Support Activity Panama City and Alligator Bayou, a tributary of St. Andrew Bay, Fla...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... City and Alligator Bayou, a tributary of St. Andrew Bay, Fla.; naval restricted area. 334.760 Section... Alligator Bayou, a tributary of St. Andrew Bay, Fla.; naval restricted area. (a) The area. The waters within... the south side of the entrance to Alligator Bayou; thence directly across the entrance to a point...

  11. 33 CFR 334.760 - Naval Support Activity Panama City and Alligator Bayou, a tributary of St. Andrew Bay, Fla...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... City and Alligator Bayou, a tributary of St. Andrew Bay, Fla.; naval restricted area. 334.760 Section... Alligator Bayou, a tributary of St. Andrew Bay, Fla.; naval restricted area. (a) The area. The waters within... the south side of the entrance to Alligator Bayou; thence directly across the entrance to a point...

  12. 33 CFR 334.760 - Naval Support Activity Panama City and Alligator Bayou, a tributary of St. Andrew Bay, Fla...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... City and Alligator Bayou, a tributary of St. Andrew Bay, Fla.; naval restricted area. 334.760 Section... Alligator Bayou, a tributary of St. Andrew Bay, Fla.; naval restricted area. (a) The area. The waters within... the south side of the entrance to Alligator Bayou; thence directly across the entrance to a point...

  13. 33 CFR 334.760 - Naval Support Activity Panama City and Alligator Bayou, a tributary of St. Andrew Bay, Fla...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... City and Alligator Bayou, a tributary of St. Andrew Bay, Fla.; naval restricted area. 334.760 Section... Alligator Bayou, a tributary of St. Andrew Bay, Fla.; naval restricted area. (a) The area. The waters within... the south side of the entrance to Alligator Bayou; thence directly across the entrance to a point...

  14. 33 CFR 334.760 - Naval Support Activity Panama City and Alligator Bayou, a tributary of St. Andrew Bay, Fla...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... City and Alligator Bayou, a tributary of St. Andrew Bay, Fla.; naval restricted area. 334.760 Section... Alligator Bayou, a tributary of St. Andrew Bay, Fla.; naval restricted area. (a) The area. The waters within... the south side of the entrance to Alligator Bayou; thence directly across the entrance to a point...

  15. Phytochemical Composition, Antifungal and Antioxidant Activity of Duguetia furfuracea A. St.-Hill

    PubMed Central

    Pinho, Francisca Valéria Soares de Araújo; da Cruz, Litiele Cezar; Rodrigues, Nathane Rosa; Waczuk, Emily Pansera; Souza, Celestina Elba Sobral; da Costa, José Galberto Martins; Athayde, Margareth Linde; de Menezes, Irwin Rose Alencar

    2016-01-01

    Background. Duguetia furfuracea is popular plant used in popular medicine. Hypothesis/Purpose. This claim evaluated the phytochemical composition of the hydroethanolic extract (HEDF), fractions of Duguetia furfuracea, and antioxidant and antifungal activity. Methods. The chemical profile was carried out by HPLC-DAD. The total phenolic contents and flavonoid components were determined by Folin-Ciocalteu and aluminium chloride reaction. The antioxidant activity was measured by scavenging of 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical and ferric reducing ability of plasma (FRAP) methods. The antifungal activity was determined by microdilution assay. Results. HPLC analysis revealed caffeic acid and rutin as major compounds (HEDF), caffeic acid and quercitrin (Mt-OH fraction), and quercitrin and isoquercitrin (Ac-OEt fraction). The highest levels of phenols and total flavonoids were found for Ac-OEt fraction, and the crude extract showed higher in vitro antioxidant potential. The antifungal activity showed synergic effect with fluconazole and EHDF against C. krusei, fluconazole and Mt-OH against C. krusei and C. tropicalis, and Ac-OE and fluconazole against C. albicans. Conclusion. The highest levels of phenols and total flavonoids were marked with antioxidant effect. This is the first report of bioactivity of the synergic effect of HEDF and fractions. More studies would be required to better clarify its mechanism of synergic action. PMID:27127550

  16. 2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline

    PubMed Central

    Chan, Wai Kit; Howe, Katherine; Clegg, James M.; Guimond, Scott E.; Price, David J.; Turnbull, Jeremy E.; Pratt, Thomas

    2015-01-01

    Heparan sulfate (HS) is a linear carbohydrate composed of polymerized uronate-glucosamine disaccharide units that decorates cell surface and secreted glycoproteins in the extracellular matrix. In mammals HS is subjected to differential sulfation by fifteen different heparan sulfotransferase (HST) enzymes of which Hs2st uniquely catalyzes the sulfation of the 2-O position of the uronate in HS. HS sulfation is postulated to be important for regulation of signaling pathways by facilitating the interaction of HS with signaling proteins including those of the Fibroblast Growth Factor (Fgf) family which signal through phosphorylation of extracellular signal-regulated kinases Erk1/2. In the developing mouse telencephalon Fgf2 signaling regulates proliferation and neurogenesis. Loss of Hs2st function phenocopies the thinned cerebral cortex of mutant mice in which Fgf2 or Erk1/2 function are abrogated, suggesting the hypothesis that 2-O-sulfated HS structures play a specific role in Fgf2/Erk signaling pathway in this context in vivo. This study investigated the molecular role of 2-O sulfation in Fgf2/Erk signaling in the developing telencephalic midline midway through mouse embryogenesis at E12.5. We examined the expression of Hs2st, Fgf2, and Erk1/2 activity in wild-type and Hs2st-/- mice. We found that Hs2st is expressed at high levels at the midline correlating with high levels of Erk1/2 activation and Erk1/2 activation was drastically reduced in the Hs2st-/- mutant at the rostral telencephalic midline. We also found that 2-O sulfation is specifically required for the binding of Fgf2 protein to Fgfr1, its major cell-surface receptor at the rostral telencephalic midline. We conclude that 2-O sulfated HS structures generated by Hs2st are needed to form productive signaling complexes between HS, Fgf2 and Fgfr1 that activate Erk1/2 at the midline. Overall, our data suggest the interesting possibility that differential expression of Hs2st targets the rostral telencephalic

  17. 2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline.

    PubMed

    Chan, Wai Kit; Howe, Katherine; Clegg, James M; Guimond, Scott E; Price, David J; Turnbull, Jeremy E; Pratt, Thomas

    2015-01-01

    Heparan sulfate (HS) is a linear carbohydrate composed of polymerized uronate-glucosamine disaccharide units that decorates cell surface and secreted glycoproteins in the extracellular matrix. In mammals HS is subjected to differential sulfation by fifteen different heparan sulfotransferase (HST) enzymes of which Hs2st uniquely catalyzes the sulfation of the 2-O position of the uronate in HS. HS sulfation is postulated to be important for regulation of signaling pathways by facilitating the interaction of HS with signaling proteins including those of the Fibroblast Growth Factor (Fgf) family which signal through phosphorylation of extracellular signal-regulated kinases Erk1/2. In the developing mouse telencephalon Fgf2 signaling regulates proliferation and neurogenesis. Loss of Hs2st function phenocopies the thinned cerebral cortex of mutant mice in which Fgf2 or Erk1/2 function are abrogated, suggesting the hypothesis that 2-O-sulfated HS structures play a specific role in Fgf2/Erk signaling pathway in this context in vivo. This study investigated the molecular role of 2-O sulfation in Fgf2/Erk signaling in the developing telencephalic midline midway through mouse embryogenesis at E12.5. We examined the expression of Hs2st, Fgf2, and Erk1/2 activity in wild-type and Hs2st-/- mice. We found that Hs2st is expressed at high levels at the midline correlating with high levels of Erk1/2 activation and Erk1/2 activation was drastically reduced in the Hs2st-/- mutant at the rostral telencephalic midline. We also found that 2-O sulfation is specifically required for the binding of Fgf2 protein to Fgfr1, its major cell-surface receptor at the rostral telencephalic midline. We conclude that 2-O sulfated HS structures generated by Hs2st are needed to form productive signaling complexes between HS, Fgf2 and Fgfr1 that activate Erk1/2 at the midline. Overall, our data suggest the interesting possibility that differential expression of Hs2st targets the rostral telencephalic

  18. The Importance of Establishing and Maintaining Continuity of Knowledge during 21st Century Nuclear Fuel Cycle Activities

    SciTech Connect

    Pickett, Chris A; Rowe, Nathan C; Younkin, James R; Wishard, Bernard; Bean, Robert; Blair, Dianna; Lawson, Ray; Weeks, George; Tolk, Keith

    2012-01-01

    During this century, the entire nuclear fuel cycle will expand and become increasingly more global, taxing both the resources and capabilities of the International Atomic Energy Agency (IAEA) to maintain an effective Continuity of Knowledge (CoK) and its ability to provide timely detection of diversion. Uranium that currently is mined and milled in one country will be converted, enriched, and fabricated into fuel for reactors in an expanding set of new countries. This expansion will make it harder to guarantee that regional activities stay regional and that diversion detection is timely unless new and sustainable tools are developed to improve inspector effectiveness. To deal with this emerging reality, the IAEA must increase its use of unattended monitoring and employ new tools and methods that enhance CoK during all phases of the fuel cycle. This approach will help provide useful information to aid in detecting undeclared activities and create opportunities for timely and appropriate responses to events well before they enter phases of greater concern (e.g., enrichment). The systems that maintain CoK of safeguarded assets rely on containment and surveillance (C/S) technologies. The 21st century fuel cycle will require increased use of these technologies and systems, plus greater implementation of unattended systems that can securely collect data when inspectors are not present.

  19. Industrializing the near-earth asteroids: Speculations on human activities in space in the latter half of the 21st century

    NASA Technical Reports Server (NTRS)

    Sercel, Joel C.

    1990-01-01

    The use of solar system resources for human industry can be viewed as a natural extension of the continual growth of our species' habitat. Motivations for human activities in space can be discussed in terms of five distinct areas: (1) information processing and collection; (2) materials processing; (3) energy production to meet terrestrial power needs; (4) the use of extraterrestrial materials; and (5) disaster avoidance. When considering 21st-Century activities in space, each of these basic motivations must be treated in light of issues likely to be relevant to the 21st-Century earth. Many of the problems facing 21st-Century earth may stem from the need to maintain the world population of 8 to 10 billion people as is projected from expected growth rates. These problems are likely to include managing the impact of industrial processes on the terrestrial biosphere while providing adequate energy production and material goods for the growing population. The most important human activities in space in the latter half of the 21st Century may be associated with harnessing the resources of the near-earth asteroids for industrial processes. These above topics are discussed with an emphasis on space industrialization.

  20. 21st Century Extravehicular Activities: Synergizing Past and Present Training Methods for Future Spacewalking Success

    NASA Technical Reports Server (NTRS)

    Moore, Sandra K.; Gast, Matthew A.

    2009-01-01

    Neil Armstrong's understated words, "That's one small step for man, one giant leap for mankind." were spoken from Tranquility Base forty years ago. Even today, those words resonate in the ears of millions, including many who had yet to be born when man first landed on the surface of the moon. By their very nature, and in the the spirit of exploration, extravehicular activities (EVAs) have generated much excitement throughout the history of manned spaceflight. From Ed White's first space walk in June of 1965, to the first steps on the moon in 1969, to the expected completion of the International Space Station (ISS), the ability to exist, live and work in the vacuum of space has stood as a beacon of what is possible. It was NASA's first spacewalk that taught engineers on the ground the valuable lesson that successful spacewalking requires a unique set of learned skills. That lesson sparked extensive efforts to develop and define the training requirements necessary to ensure success. As focus shifted from orbital activities to lunar surface activities, the required skill-set and subsequently the training methods, changed. The requirements duly changed again when NASA left the moon for the last time in 1972 and have continued to evolve through the Skylab, Space Shuttle; and ISS eras. Yet because the visits to the moon were so long ago, NASA's expertise in the realm of extra-terrestrial EVAs has diminished. As manned spaceflight again shifts its focus beyond low earth orbit, EVA success will depend on the ability to synergize the knowledge gained over 40+ years of spacewalking to create a training method that allows a single crewmember to perform equally well, whether performing an EVA on the surface of the Moon, while in the vacuum of space, or heading for a rendezvous with Mars. This paper reviews NASA's past and present EVA training methods and extrapolates techniques from both to construct the basis for future EVA astronaut training.

  1. 21st Century extravehicular activities: Synergizing past and present training methods for future spacewalking success

    NASA Astrophysics Data System (ADS)

    Moore, Sandra K.; Gast, Matthew A.

    2010-10-01

    Neil Armstrong's understated words, "That's one small step for man, one giant leap for mankind" were spoken from Tranquility Base forty years ago. Even today, those words resonate in the ears of millions, including many who had yet to be born when man first landed on the surface of the moon. By their very nature, and in the true spirit of exploration, extravehicular activities (EVAs) have generated much excitement throughout the history of manned spaceflight. From Ed White's first spacewalk in the June of 1965, to the first steps on the moon in 1969, to the expected completion of the International Space Station (ISS), the ability to exist, live and work in the vacuum of space has stood as a beacon of what is possible. It was NASA's first spacewalk that taught engineers on the ground the valuable lesson that successful spacewalking requires a unique set of learned skills. That lesson sparked extensive efforts to develop and define the training requirements necessary to ensure success. As focus shifted from orbital activities to lunar surface activities, the required skill set and subsequently the training methods changed. The requirements duly changed again when NASA left the moon for the last time in 1972 and have continued to evolve through the SkyLab, Space Shuttle, and ISS eras. Yet because the visits to the moon were so long ago, NASA's expertise in the realm of extra-terrestrial EVAs has diminished. As manned spaceflight again shifts its focus beyond low earth orbit, EVA's success will depend on the ability to synergize the knowledge gained over 40+ years of spacewalking to create a training method that allows a single crewmember to perform equally well, whether performing an EVA on the surface of the Moon, while in the vacuum of space, or heading for a rendezvous with Mars. This paper reviews NASA's past and present EVA training methods and extrapolates techniques from both to construct the basis for future EVA astronaut training.

  2. George Darwin lecture: The expansion rate of the universe

    NASA Astrophysics Data System (ADS)

    Freedman, Wendy

    2002-02-01

    Wendy Freedman presents the 2001 George Darwin Lecture on present and future advances in cosmology. Modern cosmology is undergoing an explosion of observational and experimental results that is in turn driving significant theoretical advances and a dynamic interface between theory and experiment. As a consequence, cosmological parameters are becoming much more precisely constrained. In this, the George Darwin lecture for 2001, I look back at the some of the advances made since Edwin Hubble presented his George Darwin lecture in 1953, and look ahead to the resolution of significant cosmological uncertainties.

  3. Chemical composition and biological activities of the essential oils from Duguetia lanceolata St. Hil. barks.

    PubMed

    Sousa, Orlando V; Del-Vechio-Vieira, Glauciemar; Alves, Maria S; Araújo, Aílson A L; Pinto, Míriam A O; Amaral, Maria P H; Rodarte, Mírian P; Kaplan, Maria A C

    2012-01-01

    Essential oils of Duguetia lanceolata barks, obtained at 2 (T2) and 4 h (T4), were identified by gas chromatography and gas chromatography/mass spectrometry. β-elemene (12.7 and 14.9%), caryophyllene oxide (12.4 and 10.7%) and β-selinene (8.4 and 10.4%) were the most abundant components in T2 and T4, respectively. The essential oils inhibited the growth of Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli and Candida albicans. The essential oils were cytotoxic against brine shrimp. The extraction time influenced the chemical composition and biological activities of essential oils obtained from the barks of D. lanceolata. PMID:22976469

  4. Digital imaging of autoradiographs from paintings by Georges de La Tour (1593-1652)

    NASA Astrophysics Data System (ADS)

    Fischer, C.-O.; Gallagher, M.; Laurenze, C.; Schmidt, Ch; Slusallek, K.

    1999-11-01

    The artistic work of the painter Georges de La Tour has been studied very intensively in the last few years, mainly by French and US-American art historians and natural scientists. To support the in-depth analysis of two paintings from the Kimbell Art Museum in Fort Worth, Texas, USA, two similar paintings from the Gemäldegalerie Berlin have been investigated. The method of neutron activation autoradiography has been applied using imaging plates with digital image processing.

  5. Stable Ectopic Expression of ST6GALNAC5 Induces Autocrine MET Activation and Anchorage-Independence in MDCK Cells

    PubMed Central

    Chu, Chia; Bottaro, Donald P.; Betenbaugh, Michael J.; Shiloach, Joseph

    2016-01-01

    The epithelial-mesenchymal transition (EMT) is a complex cancer progression that can boost the metastatic potential of transformed cells by inducing migration, loss of cell adhesion, and promoting proliferation under anchorage-independent conditions. A DNA microarray analysis was performed comparing parental anchorage-dependent MDCK cells and anchorage-independent MDCK cells that were engineered to express human siat7e (ST6GALNAC5). The comparison identified several genes involved in the EMT process that were differentially expressed between the anchorage-dependent and the anchorage-independent MDCK cell lines. The hepatocyte growth factor gene (hgf) was found to be over-expressed in the engineered MDCK-siat7e cells at both transcription and protein expression levels. Phosphorylation analysis of the MET receptor tyrosine kinase confirmed the activation of an autocrine loop of the HGF/ MET signaling pathway in the MDCK-siat7e cells. When MET activities were suppressed by using the small-molecular inhibitor drug PF-02341066 (Crizotinib), the anchorage-independent MDCK-siat7e cells reverted to the cellular morphology of the parental anchorage-dependent MDCK cells. These observations indicate that the MET receptor plays a central role in the growth properties of the MDCK cells and its phosphorylation status is likely dependent on sialylation. Further investigation of the downstream signaling targets in the MET network showed that the degree of MDCK cell adhesion correlated with secretion levels of a matrix metalloproteinase, MMP1, suggesting a role of metalloproteinases in the EMT process. These results demonstrate that in addition to its application in biotechnology processes, MDCK-siat7e may serve as a model cell for metastasis studies to decipher the sequence of events leading up to the activation of EMT. PMID:26848584

  6. Magnetoplasmadynamcis - Portrait of George P. Wood

    NASA Technical Reports Server (NTRS)

    1962-01-01

    Portrait of George P. Wood: Wood was head of Magnetoplasmadynamcis' (MPD) Magnetohydrodynamics Section. 'Through the transition period of 1957 and 1958, researchers at the lab continued to seek new ways to accelerate hot plasmas to the tremendous velocities of reentry flight. In a method devised by Langley MPD enthusiast George Wood, a hot gas was fed into a tube, then the body force of crossed electric and magnetic fields was used to accelerate the gas to the point where a mixture of disassociated, high-enthalpy flow would reproduce the very high Mach numbers of hypersonic flight. At NASA's First Anniversary Inspection in 1959, Langley engineers demonstrated a crude version of Wood's crossed-field plasma accelerator. It produced a flash of light, a loud bang, a startled audience, and a belief in the promise of major new scientific findings. Nearly everyone was excited by the potential of plasma accelerators. When John Stack first heard about the facility, he exclaimed, 'This is great!' Stack felt that Langley should call the device something grand; he proposed the awe-inspiring name, the 'Trans-Satellite-Velocity Wind Tunnel.' Given the limited performance of Wood's early version of the experimental accelerator, such a pretentious name would have been a poor choice. As part of a guided tour for top officials from NASA headquarters in late 1959, Langley hoped to show off the radically new plasma acceleration device. almost comically, it did not work. . . . The concept behind Wood's crossed-field plasma accelerator was sound: it was an application of a 130-year-old theory of electromagnetic force that had been expressed by Amp*re in the 1820s. Langley researchers kept fiddling with the pilot model until in 1960 they successfully demonstrated its feasibility. Having done so, they continued research on larger, more powerful versions of the device. One version, the 20-megawatt plasma accelerator, was completed in 1966 at a cost of more than $1 million. With this

  7. Lung clearance of neutron-activated Mount St. Helens volcanic ash in the rat.

    PubMed

    Wehner, A P; Wilerson, C L; Stevens, D L

    1984-10-01

    To determine pulmonary deposition and clearance of inhaled volcanic ash, rats received a single 60-min, nose-only exposure to neutron-activated ash. Over a period of 128 days after exposure, the rats were sacrificed in groups of five animals. Lungs were analyzed for the radionuclide tracers 46Sc, 59Fe, and 60Co by gamma-ray spectrometry. The alveolar ash burdens, determined by the radionuclides 46Sc and 59Fe, are in good agreement for the majority of samples analyzed, indicating ash particulate levels in the lungs, rather than leached radionuclides. The ash deposition estimates based on 60Co were appreciably lower for the lungs, indicating that 60Co leached from the ash. Approximately 110 micrograms ash, or 6% of the inhaled ash, was initially retained in the deep lung. The biological half-time of the alveolar ash burden was 39 days. After 90 days, the mean lung burden had decreased to about 20% of its initial value; 128 days after exposure, about 10% remained. PMID:6489290

  8. Lund clearance of neutron-activated Mount St. Helens volanic ash in the rat

    SciTech Connect

    Wehner, A.P.; Wilerson, C.L.; Stevens, D.L.

    1984-10-01

    To determine pulmonary deposition and clearance of inhaled volcanic ash, rats received a single 60-min, nose-only exposure to neutron-activated ash. Over a period of 128 days after exposure, the rats were sacrificed in groups of five animals. Lungs were analyzed for the radionuclide tracers /sup 46/Sc, /sup 59/Fe, and /sup 60/Co by ..gamma..-ray spectrometry. The alveolar ash burdens, detemined by the radionuclides /sup 46/Sc and /sup 59/Fe, are in good agreement for the majority of samples analyzed, indicating ash particulate levels in the lungs, rather than leached radionuclides. The ash deposition estimates based on /sup 60/Co were appreciably lower for the lungs, indicating that /sup 60/Co leached from the ash. Approximately 110 ..mu..g ash, or 6% of the inhaled ash, was initially retained in the deep lung. The biological half-time of the alveolar ash burden was 39 days. After 90 days, the mean lung burden had decreased to about 20% of its initial value; 128 days after exposure, about 10% remained.

  9. Ensemble projections of wildfire activity and carbonaceous aerosol concentrations over the western United States in the mid-21st century

    NASA Astrophysics Data System (ADS)

    Yue, X.; Mickley, L. J.; Logan, J. A.

    2010-12-01

    We estimate future wildfire activity over the western United States during the mid-21st century (2046-2065), based on ensemble results from 16 models following the IPCC A1B scenario. Regression models and a parameterization model of area burned (AB) are developed for the projection. The ecoregion-based regression models consider the meteorological impacts from both the current and previous years on the regional AB; the correlation coefficients between the predicted and observed annual AB range from 0.59 to 0.85 during 1981-2000 for six ecoregions. The parameterization model calculates the effects of temperature, precipitation, and relative humidity on daily AB; the predicted monthly total AB over the western US is highly correlated with observations with a normal (logarithmic) correlation coefficient of 0.73 (0.90) for 300 months (1980-2004). The meteorological fields under the A1B scenario from 15 IPCC models and a general circulation model (NASA/GISS GCM 3) are applied to the fire models to estimate AB during 2046-2065. We calculate that the annual AB will increase by 21~124% (regression models) and 40~198% (parameterization) over six ecoregions in the western US at midcentury relative to present day; the length of fire season will extend by 11.1% for the warmer and drier climate. We also examine the impact of the changing climate on the fuel load with a dynamic vegetation model LPJ driven by future meteorology from the GISS GCM 3; it shows that the fuel load over western US experiences small changes because of the short time period from 2000 to 2050. Based on the projected fuel load and the AB calculations, we estimate that the annual total biomass burning over western US will increase by 68% (regression models) or as much as 161% (parameterization). We further investigate the impact of the changing fire emission on the carbonaceous aerosol concentrations over the western United States in the mid-21st century using the chemistry transport model GEOS-Chem driven

  10. Projection of wildfire activity in southern California in the mid-21st century

    PubMed Central

    Mickley, Loretta J.; Logan, Jennifer A.

    2014-01-01

    We estimate area burned in southern California at mid-century (2046-2065) for the Intergovernmental Panel on Climate Change (IPCC) A1B scenario. We develop both regressions and a parameterization to predict area burned in three ecoregions, and apply present-day (1981-2000) and future meteorology from the suite of general circulation models (GCMs) to these fire prediction tools. The regressions account for the impacts of both current and antecedent meteorological factors on wildfire activity and explain 40-46% of the variance in area burned during 1980-2009. The parameterization yields area burned as a function of temperature, precipitation, and relative humidity, and includes the impact of Santa Ana wind and other geographical factors on wildfires. It explains 38% of the variance in area burned over southern California as a whole, and 64% of the variance in southwestern California. The parameterization also captures the seasonality of wildfires in three ecoregions of southern California. Using the regressions, we find that area burned likely doubles in Southwestern California by midcentury, and increases by 35% in the Sierra Nevada and 10% in central western California. The parameterization suggests a likely increase of 40% in area burned in southwestern California and 50% in the Sierra Nevada by midcentury. It also predicts a longer fire season in southwestern California due to warmer and drier conditions on Santa Ana days in November. Our method provides robust estimates of area burned at midcentury, a key metric which can be used to calculate the fire-related effects on air quality, human health, and the associated costs. PMID:25346575

  11. Projection of wildfire activity in southern California in the mid-21st century.

    PubMed

    Yue, Xu; Mickley, Loretta J; Logan, Jennifer A

    2014-10-01

    We estimate area burned in southern California at mid-century (2046-2065) for the Intergovernmental Panel on Climate Change (IPCC) A1B scenario. We develop both regressions and a parameterization to predict area burned in three ecoregions, and apply present-day (1981-2000) and future meteorology from the suite of general circulation models (GCMs) to these fire prediction tools. The regressions account for the impacts of both current and antecedent meteorological factors on wildfire activity and explain 40-46% of the variance in area burned during 1980-2009. The parameterization yields area burned as a function of temperature, precipitation, and relative humidity, and includes the impact of Santa Ana wind and other geographical factors on wildfires. It explains 38% of the variance in area burned over southern California as a whole, and 64% of the variance in southwestern California. The parameterization also captures the seasonality of wildfires in three ecoregions of southern California. Using the regressions, we find that area burned likely doubles in Southwestern California by midcentury, and increases by 35% in the Sierra Nevada and 10% in central western California. The parameterization suggests a likely increase of 40% in area burned in southwestern California and 50% in the Sierra Nevada by midcentury. It also predicts a longer fire season in southwestern California due to warmer and drier conditions on Santa Ana days in November. Our method provides robust estimates of area burned at midcentury, a key metric which can be used to calculate the fire-related effects on air quality, human health, and the associated costs. PMID:25346575

  12. George Orwell and the Theory of Totalitarianism: A 1984 Retrospective.

    ERIC Educational Resources Information Center

    Enteen, George M.

    1984-01-01

    Discusses the use of George Orwell's "1984" in a college-level course on communism and totalitarianism. Draws from personal experiences during a year's graduate study in Moscow to examine Orwell's perceptions of the Soviet Union. (AYC)

  13. 4. Historic American Buildings Survey George Harkness III, Photographer, April ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey George Harkness III, Photographer, April 10, 1934 MEASURING THE WEST ELEVATION (REAR) - Jean Baptiste Valle House, 99 South Main Street (Northwest corner of Main & Market Streets), Sainte Genevieve, Ste. Genevieve County, MO

  14. 56. Historic American Buildings Survey, George A. Eisenman, Photographer, 1969 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    56. Historic American Buildings Survey, George A. Eisenman, Photographer, 1969 NORTHWEST VIEW IN PASSAGE OF THE EAST BASTION TOWARDS THE ENTRANCE GATES. - Fort Mifflin, Mud Island, Marine & Penrose Ferry Roads, Philadelphia, Philadelphia County, PA

  15. 1. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 GENERAL VIEW WEST ALONG K STREET - Ray's Warehouse & Office, 3260-3262 K Street Northwest, Washington, District of Columbia, DC

  16. 2. Historic American Buildings Survey George M. Cushing, Photographer October ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey George M. Cushing, Photographer October 1967 ENTRANCE HALL AND STAIRS, LOOKING NORTHWEST - Guyot-Horsford House & Stable, 27 Craigie Street, Cambridge, Middlesex County, MA

  17. 3. Historic American Buildings Survey, George A. Eisenman, Photographer April, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey, George A. Eisenman, Photographer April, 1961 FIREPLACE AND STAIRWAY IN ROOM #2 ON FIRST FLOOR. - Shoomac Park, Ridge Avenue & Wissahickon Drive, Philadelphia, Philadelphia County, PA

  18. 5. Historic American Buildings Survey, George A. Eisenman, Photographer April, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Historic American Buildings Survey, George A. Eisenman, Photographer April, 1961 CUPBOARD AND CELLAR DOOR IN ROOM #3 ON FIRST FLOOR, SHOWING BEADED FLUSH BOARDING. - Shoomac Park, Ridge Avenue & Wissahickon Drive, Philadelphia, Philadelphia County, PA

  19. 4. Historic American Buildings Survey, George A. Eisenman, Photographer April, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey, George A. Eisenman, Photographer April, 1961 OLD CUPBOARD IN ROOM #2 ON FIRST FLOOR. - Shoomac Park, Ridge Avenue & Wissahickon Drive, Philadelphia, Philadelphia County, PA

  20. 6. Historic American Buildings Survey, George A. Eisenman, Photographer April, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey, George A. Eisenman, Photographer April, 1961 FIREPLACE, PANELING AND CLOSET DOORS IN ROOM #3 ON SECOND FLOOR. - Shoomac Park, Ridge Avenue & Wissahickon Drive, Philadelphia, Philadelphia County, PA

  1. 2. Historic American Buildings Survey, W. Eugene George, Jr., Photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey, W. Eugene George, Jr., Photographer July, 1961 WEST ELEVATION (RIO GRANDE RIVER FACADE). - Leocadia Leandro Garcia House, Southwest corner of Main Plaza, Roma Creek, Starr County, TX

  2. 3. Historic American Buildings Survey, W. Eugene George, Jr., Photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey, W. Eugene George, Jr., Photographer July, 1961 NORTHWEST ELEVATION (RIO GRANDE RIVER FACADE). - Leocadia Leandro Garcia House, Southwest corner of Main Plaza, Roma Creek, Starr County, TX

  3. 12. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 LOCK #4 GATES, AND 'TOW PATH ROW' BUILDINGS - Chesapeake & Ohio Canal, Georgetown Section, East & West parallel to M Street Northwest, Washington, District of Columbia, DC

  4. 97. George Newman Photographer. VIEW OF SOUTH END OF THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    97. George Newman Photographer. VIEW OF SOUTH END OF THE NEBRASKA SWING SPAN SHOWING THE BRIDGE OPEN APRIL 13, 1945. - Pacific Shortline Bridge, U.S. Route 20,spanning Missouri River, Sioux City, Woodbury County, IA

  5. 98. George Newman Photographer. VIEW OF THE NEBRASKA SWING SPAN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    98. George Newman Photographer. VIEW OF THE NEBRASKA SWING SPAN OPEN FOR RIVER PASSAGE. APRIL 13, 1945. - Pacific Shortline Bridge, U.S. Route 20,spanning Missouri River, Sioux City, Woodbury County, IA

  6. 51. Historic American Buildings Survey, George A. Eisenman, Photographer, 1969 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    51. Historic American Buildings Survey, George A. Eisenman, Photographer, 1969 DETAIL VIEW OF FIREPLACE IN NORTHEAST CASEMATE OF THE EAST BASTION. - Fort Mifflin, Mud Island, Marine & Penrose Ferry Roads, Philadelphia, Philadelphia County, PA

  7. 1. HISTORIC AMERICAN BUILDINGS SURVEY George Neuschafer, photographer. (Reproduction of) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. HISTORIC AMERICAN BUILDINGS SURVEY George Neuschafer, photographer. (Reproduction of) EXTERIOR VIEW OF HOUSE IN 1878-81. (Mr. and Mrs. Joseph Williamson and two daughters in foreground.) - Clifford-Williamson House, Pattenburg, Hunterdon County, NJ

  8. 3. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 FIRST FLOOR, FRONT ROOM, FIREPLACE IN SOUTHEAST CORNER - Joseph Careleton House, 1052-54 Potomac Street Northwest, Washington, District of Columbia, DC

  9. 5. Historic American Buildings Survey, George A. Eisenman, Photographer, 1969 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Historic American Buildings Survey, George A. Eisenman, Photographer, 1969 NORTHWEST ELEVATION SHOWING GHOST OF STAIRWAY. - Fort Mifflin, Soldiers' Barracks, Mud Island, Marine & Penrose Ferry Roads, Philadelphia, Philadelphia County, PA

  10. 3. Historic American Buildings Survey George Neuschafer, Photographer June 25, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey George Neuschafer, Photographer June 25, 1941 EXTERIOR - WINDOW DETAIL - NORTHEAST ELEVATION - David R. Haring House, 202 Old Tappan Road, Old Tappan, Bergen County, NJ

  11. 7. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 BASEMENT, FIREPLACE SUPPORT IN SOUTHWEST CORNER - Adams-Mason House, 1072 Thomas Jefferson Street Northwest, Washington, District of Columbia, DC

  12. 4. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 FIRST FLOOR, FRONT ROOM, FIREPLACE SOUTH WALL - Adams-Mason House, 1072 Thomas Jefferson Street Northwest, Washington, District of Columbia, DC

  13. 5. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 SECOND FLOOR, FRONT ROOM, FIREPLACE SOUTH WALL - Adams-Mason House, 1072 Thomas Jefferson Street Northwest, Washington, District of Columbia, DC

  14. 6. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 BASEMENT: FIREPLACE SUPPORT ARCH, WEST WALL, UNDER BRICK ELL - Adams-Mason House, 1072 Thomas Jefferson Street Northwest, Washington, District of Columbia, DC

  15. 3. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 DETAIL, WINDOWS OF BRICK ELL - Adams-Mason House, 1072 Thomas Jefferson Street Northwest, Washington, District of Columbia, DC

  16. 1. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 WEST AND SOUTH SIDES - National Bank of Washington, 301 Seventh Street, Northwest at Indiana Avenue & C Street, Washington, District of Columbia, DC

  17. 2. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey George Eisenman, Photographer Summer 1967 SOUTH ELEVATION - National Bank of Washington, 301 Seventh Street, Northwest at Indiana Avenue & C Street, Washington, District of Columbia, DC

  18. Dundee Canal Industrial Historic District, Beginning at George Street in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Dundee Canal Industrial Historic District, Beginning at George Street in Passaic & extending north along Dundee Canal approximately 1.2 miles to Canal headgates opposite East Clifton Avenue in Clifton, Passaic, Passaic County, NJ

  19. 14. Photocopy of photograph (original print in possession of George ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photocopy of photograph (original print in possession of George Pavlica, Bovey, MN) 1913, photographer unknown, cityscape with tower in background - Bovey Water Tower, Eighth Avenue & T.H. 169, Bovey, Itasca County, MN

  20. [Georg Friedrich Händel's eye disease].

    PubMed

    Evers, S

    1993-09-01

    In his last years Georg Friedrich Händel suffered from a loss of sight not definitely to be defined. Based on primary sources, this disease, often mentioned in his biographies, is described and analysed. Altogether, Händel's eye-disease can be best interpreted as a central vascular disorder with degeneration of retina or with ischemic changes in the corresponding nuclei or tractus, complicated by a simple senile or post-traumatic cataract. Händel's profile of risk factors points most probably to a vascular degeneration of macula or a damage of choroidal vessels. Händel's eye-disease must be seen in relation to his cerebro-vascular disorder. His most probable strokes as well as his loss of sight were of vital importance in his biography, as is reflected even by his compositions. However, both disorders did not fundamentally influence his creativity. Only in a few compositions a reference to the loss of sight can be found. Apart from changes in concert-practising during his last years Händel's eye-disease, however, had no direct effect on his musical work. PMID:8264215

  1. Marshall's George Hopson Recieves NASA's Highest Honors

    NASA Technical Reports Server (NTRS)

    2003-01-01

    After four decades of contribution to America's space program, George Hopson, manager of the Space Shuttle Main Engine Project at Marshall Space Flight Center, accepted NASA's Distinguished Service Medal. Awarded to those who, by distinguished ability or courage, have made a personal contribution to the NASA mission, NASA's Distinguished Service Medal is the highest honor NASA confers. Hopson's contributions to America's space program include work on the country's first space station, Skylab; the world's first reusable space vehicle, the Space Shuttle; and the International Space Station. Hopson joined NASA's Marshall team as chief of the Fluid and Thermal Systems Branch in the Propulsion Division in 1962, and later served as chief of the Engineering Analysis Division of the Structures and Propulsion Laboratory. In 1979, he was named director of Marshall's Systems Dynamics Laboratory. In 1981, he was chosen to head the Center's Systems Analysis and Integration. Seven years later, in 1988, Hopson was appointed associate director for Space Transportation Systems and one year later became the manager of the Space Station Projects Office at Marshall. In 1994, Hopson was selected as deputy director for Space Systems in the Science and Engineering Directorate at Marshall where he supervised the Chief Engineering Offices of both marned and unmanned space systems. He was named manager of the Space Shuttle Main Engine Project in 1997. In addition to the Distinguished Service Medal, Hopson has also been recognized with the NASA Outstanding Leadership Medal and NASA's Exceptional Service Medal.

  2. Space Weather At George Mason University

    NASA Astrophysics Data System (ADS)

    Poland, A. I.; Zhang, J.

    2005-05-01

    George Mason University (GMU), located in Fairfax, Virginia has an exciting and rapidly growing set of graduate programs in Astrophysics, Space Weather, Planetary Sciences, and Earth Sciences. The faculty members in these programs are affiliated with the Department of Physics and Astronomy and the School of Computational Sciences (SCS). The synergy between these two departments creates opportunities for learning not found in traditional programs. Our curriculum emphasizes multi-disciplinary science that crosses traditional department boundaries. Space Weather/solar terrestrial physics is one of these multi-disciplinary areas. We expect our students to develop a deep understanding of the Sun, the heliosphere, geospace, and their interactions; we emphasize a systems view. The graduate program in Space Weather at GMU offers degrees at the Masters (M.S.) and Doctoral (Ph. D) levels through the School of Computational Sciences (SCS) and the Department of Physics and Astronomy of the College of Arts and Sciences (CAS). A wide variety of relevant courses are offered through (SCS) in partnership with (CAS). Students also have the opportunity to do research associated with the Goddard Space Flight Center and the Navel Research Laboratory. For more information on the program see: http://www.scs.gmu.edu/spaceweather/ Undergraduates and people from local industry are also taking some of our courses to further their education in this area. Many of them are finding the lectures directly relevant to their daily work, such as satellite orbit maintenance.

  3. George Gamow: Scientific Amateur and Polymath

    NASA Astrophysics Data System (ADS)

    Harper, Eamon

    George Gamow (1904-1968) was among the first of the many brilliant scientists who forsook Europe for the United States in the early 1930s. Although most were fleeing the fascist imperium of Hitler and Mussolini, Gamow was one of a few who managed to escape the burgeoning despotism of Stalin in the Soviet Union. His early application of quantum mechanics to the atomic nucleus and his subsequent insight into the role played by the physics of the atom and its nucleus in stars, galaxies, and the universe identifies him as a scientist of unusual genius. Gamow displayed a boisterous, infectious - almost Rutherfordian - interest in all aspects of pure science. His interests were broad and his industry prodigious. His scientific output covered areas as diverse as nuclear physics, astrophysics, cosmology, biological genetics, and the fascinating question of the relationship of the large-scale structure and development of the universe to the properties of elementary particles and fields. He also was an immensely imaginative and prolific author of popular expositions on scientific subjects. One who is as well-known for his authorship of the Mr. Tompkins series of science popularizations as for his contributions to the development of the physical consequences of the big-bang theory of the expanding universe and the prediction of the cosmic background radiation must be unique in the scientific pantheon.

  4. Source regions for recruitment of Calanus finmarchicus to Georges Bank: evidence from molecular population genetic analysis of mtDNA

    NASA Astrophysics Data System (ADS)

    Bucklin, Ann; Kocher, Thomas D.

    Molecular population genetic analysis has provided evidence that the copepod, Calanus finmarchicus, of the Labrador Current, Gulf of St Lawrence, Scotian Shelf, Gulf of Maine, and Georges Bank constitute a single, interbreeding population. The DNA sequence of a 350 base pair portion of the mitochondrial large subunit (16S) ribosomal RNA (rRNA) gene was determined for a total of 72 individuals collected in 1992, and 110 individuals collected in 1993 from these regions. There was significant heterogeneity in haplotype frequencies among the samples collected in 1992, but this heterogeneity did not resolve into regional patterns. The only regional differences seen were between pooled samples of the western N. Atlantic and those of the Norwegian Sea. There were no significant differences in haplotype frequencies among the samples collected in 1993, and fewer haplotypes were observed in these samples. Intraspecific molecular variation was typical of other marine species: there were 29 haplotypes among the 182 individuals sequenced. The frequency distribution of the haplotypes was highly skewed: 128 individuals shared one haplotype and 19 individuals were unique. There were 24 variable sites among the 350 bases sequenced; estimated nucleotide diversity was 0.0042. The genetic character of C. finmarchicus populations in the western N. Atlantic was stable over time in that three of the haplotypes (including the most abundant) occurred in both 1992 and 1993. However, haplotype frequencies differed significantly between the two years. The lack of regional structure in the 1992 samples and the genetic homogeneity of samples collected in 1993 across the domain from the Labrador Current to the Gulf of St Lawrence to Georges Bank and the Gulf of Maine indicated that there is significant gene flow across this region. The persistent genetic pattern suggests that the Gulf of St Lawrence may be an important source region for recruitment of C. finmarchicus to Georges Bank

  5. Ensemble projections of wildfire activity and carbonaceous aerosol concentrations over the western United States in the mid-21st century

    PubMed Central

    Yue, Xu; Mickley, Loretta J.; Logan, Jennifer A.; Kaplan, Jed O.

    2013-01-01

    We estimate future wildfire activity over the western United States during the mid-21st century (2046–2065), based on results from 15 climate models following the A1B scenario. We develop fire prediction models by regressing meteorological variables from the current and previous years together with fire indexes onto observed regional area burned. The regressions explain 0.25–0.60 of the variance in observed annual area burned during 1980–2004, depending on the ecoregion. We also parameterize daily area burned with temperature, precipitation, and relative humidity. This approach explains ~0.5 of the variance in observed area burned over forest ecoregions but shows no predictive capability in the semi-arid regions of Nevada and California. By applying the meteorological fields from 15 climate models to our fire prediction models, we quantify the robustness of our wildfire projections at mid-century. We calculate increases of 24–124% in area burned using regressions and 63–169% with the parameterization. Our projections are most robust in the southwestern desert, where all GCMs predict significant (p<0.05) meteorological changes. For forested ecoregions, more GCMs predict significant increases in future area burned with the parameterization than with the regressions, because the latter approach is sensitive to hydrological variables that show large inter-model variability in the climate projections. The parameterization predicts that the fire season lengthens by 23 days in the warmer and drier climate at mid-century. Using a chemical transport model, we find that wildfire emissions will increase summertime surface organic carbon aerosol over the western United States by 46–70% and black carbon by 20–27% at midcentury, relative to the present day. The pollution is most enhanced during extreme episodes: above the 84th percentile of concentrations, OC increases by ~90% and BC by ~50%, while visibility decreases from 130 km to 100 km in 32 Federal Class 1

  6. Ensemble projections of wildfire activity and carbonaceous aerosol concentrations over the western United States in the mid-21st century

    NASA Astrophysics Data System (ADS)

    Yue, Xu; Mickley, Loretta J.; Logan, Jennifer A.; Kaplan, Jed O.

    2013-10-01

    We estimate future wildfire activity over the western United States during the mid-21st century (2046-2065), based on results from 15 climate models following the A1B scenario. We develop fire prediction models by regressing meteorological variables from the current and previous years together with fire indexes onto observed regional area burned. The regressions explain 0.25-0.60 of the variance in observed annual area burned during 1980-2004, depending on the ecoregion. We also parameterize daily area burned with temperature, precipitation, and relative humidity. This approach explains ˜0.5 of the variance in observed area burned over forest ecoregions but shows no predictive capability in the semi-arid regions of Nevada and California. By applying the meteorological fields from 15 climate models to our fire prediction models, we quantify the robustness of our wildfire projections at midcentury. We calculate increases of 24-124% in area burned using regressions and 63-169% with the parameterization. Our projections are most robust in the southwestern desert, where all GCMs predict significant (p < 0.05) meteorological changes. For forested ecoregions, more GCMs predict significant increases in future area burned with the parameterization than with the regressions, because the latter approach is sensitive to hydrological variables that show large inter-model variability in the climate projections. The parameterization predicts that the fire season lengthens by 23 days in the warmer and drier climate at midcentury. Using a chemical transport model, we find that wildfire emissions will increase summertime surface organic carbon aerosol over the western United States by 46-70% and black carbon by 20-27% at midcentury, relative to the present day. The pollution is most enhanced during extreme episodes: above the 84th percentile of concentrations, OC increases by ˜90% and BC by ˜50%, while visibility decreases from 130 km to 100 km in 32 Federal Class 1 areas in

  7. Ensemble projections of wildfire activity and carbonaceous aerosol concentrations over the western United States in the mid-21st century.

    PubMed

    Yue, Xu; Mickley, Loretta J; Logan, Jennifer A; Kaplan, Jed O

    2013-10-01

    We estimate future wildfire activity over the western United States during the mid-21(st) century (2046-2065), based on results from 15 climate models following the A1B scenario. We develop fire prediction models by regressing meteorological variables from the current and previous years together with fire indexes onto observed regional area burned. The regressions explain 0.25-0.60 of the variance in observed annual area burned during 1980-2004, depending on the ecoregion. We also parameterize daily area burned with temperature, precipitation, and relative humidity. This approach explains ~0.5 of the variance in observed area burned over forest ecoregions but shows no predictive capability in the semi-arid regions of Nevada and California. By applying the meteorological fields from 15 climate models to our fire prediction models, we quantify the robustness of our wildfire projections at mid-century. We calculate increases of 24-124% in area burned using regressions and 63-169% with the parameterization. Our projections are most robust in the southwestern desert, where all GCMs predict significant (p<0.05) meteorological changes. For forested ecoregions, more GCMs predict significant increases in future area burned with the parameterization than with the regressions, because the latter approach is sensitive to hydrological variables that show large inter-model variability in the climate projections. The parameterization predicts that the fire season lengthens by 23 days in the warmer and drier climate at mid-century. Using a chemical transport model, we find that wildfire emissions will increase summertime surface organic carbon aerosol over the western United States by 46-70% and black carbon by 20-27% at midcentury, relative to the present day. The pollution is most enhanced during extreme episodes: above the 84(th) percentile of concentrations, OC increases by ~90% and BC by ~50%, while visibility decreases from 130 km to 100 km in 32 Federal Class 1 areas in

  8. Recent turbidity current activity in sediment-starved submarine canyons (Northwestern Gulf of St. Lawrence, Eastern Canada)

    NASA Astrophysics Data System (ADS)

    Normandeau, Alexandre; Lajeunesse, Patrick; St-Onge, Guillaume; Bourgault, Daniel; Neumeier, Urs

    2016-04-01

    Submarine canyons are known to be main conduits for the transport of sediments to deep-sea basins, mostly by turbidity currents. Turbidity currents flowing in submarine canyons are mostly triggered by hyperpycnal flows, small to large slope failures and advection of shelf sediment offshore. In these contexts, sediment supply is necessary to maintain canyon activity over time. In 2007, a high-resolution mapping of small-scale submarine canyons offshore Pointe-des-Monts (NW Gulf of St. Lawrence, Eastern Canada) revealed a series of incisions characterized by the presence of numerous confined crescentic bedforms. The repeat mapping of the canyons in 2012 and 2015 revealed that the bedforms migrated upslope, indicating that they are cyclic steps produced by supercritical flows. Surprisingly, the comparison of multibeam surveys did not show any evidence of slope failures that could have triggered the turbidity currents responsible for recent bedform migration. Additionally, the rocky shores and coastal shelf do not supply sediments to these canyons, thus excluding turbidity current triggers such as advection of shelf sediments or hyperpycnal flows. In this context, we suggest that hydrodynamic processes are responsible for suspending in-situ sediments, which then may flow as turbidity currents when density of the water-sediment mixture is high enough. ADCPs deployed for 3,5 months during the summer of 2015 revealed along-canyon currents following tidal cycles with speeds up to 0.4 m/s, which were not strong enough to produce bedform migration. Therefore, the currents responsible for bedforms occur during infrequent events or during winter conditions, which both require longer instrument time-series to be observed.

  9. Evaluation of liver histopathology and EROD activity in St. Lawrence lake sturgeon (Acipenser fulvescens) in comparison with a reference population

    SciTech Connect

    Rousseaux, C.G. ||; Branchaud, A.; Spear, P.A.

    1995-05-01

    In an attempt to evaluate the effects of contaminants on the lake sturgeon Acipenser fulvescens, fish were netted from two sites: Riviere des Prairies, confluent with the St. Lawrence River near Montreal, and a reference site on the upper reaches of the Ottawa River in the La Verendrye Park. Livers of fish collected from the Riviere des Prairies were difficult to homogenize, and they left behind strands of what appeared to be connective tissue. Suspecting hepatic fibrosis, the authors decided to evaluate the livers for histopathologic changes. Nineteen adult lake sturgeon (eleven male and eight female) were examined. Following fixation, routine processing, sectioning, and staining with hematoxylin and eosin, microscopic evaluation revealed the following: Sections taken from livers of fish from the Riviere des Prairies site showed excessive fat accumulation and often severe chronic-active cholangiohepatitis. Bile duct proliferation (p < 0.0001), periportal fibrosis (p < 0.0001), inflammation (p < 0.001), and fat accumulation (p < 0.05) were more pronounced in the fish from the Riviere des Prairies site. Melano-macrophage centers appeared to be both paler and gave the appearance of fewer numbers (p < 0.01). Livers from lake sturgeon taken from the reference site had a more normal appearance. The EROD levels were also significantly induced in these fish (reference 3.39 {+-} 0.57; Riviere des Prairies site 8.21 {+-} 0.87 pmol/mg protein/min; p < 0.0005). The EROD levels positively correlated with bile duct proliferation (r{sup 2} = 0.44; p = 0.001) and periportal fibrosis (r{sup 2} = 0.41; p = 0.002). Despite the statistical associations above, the authors cannot categorically state that contaminants are the sole cause of the lesions seen.

  10. Obituary: George West Wetherill, 1925-2006

    NASA Astrophysics Data System (ADS)

    Boss, Alan Paul

    2006-12-01

    George W. Wetherill, 1997 National Medal of Science recipient, died from heart failure on 19 July 2006, at his Washington, DC home. Wetherill can be rightfully called the father of modern theories of the formation of the Earth. Prior to the first Protostars and Planets meeting in Tucson in 1978, planet formation theories tended to be eccentric concoctions created by distinguished senior scientists who had earned the right to dream a little bit about how our Solar System had formed. Wetherill was in the vanguard of the effort to place planet formation theory on a solid basis. Born in Philadelphia on 12 August 1925, Wetherill served in the U.S. Navy during World War II, teaching radar at the Naval Research Laboratory in the District. He graduated from the University of Chicago in 1953 after receiving a succession of degrees: Ph.B., S.B., S.M., and Ph.D. Wetherill joined the staff of the Carnegie Institution's Department of Terrestrial Magnetism (DTM), located in northwest Washington, DC, in 1953. He and his colleagues at DTM and Carnegie's Geophysical Laboratory proceeded to revolutionize the field of geochemical dating of rocks by applying the physics he had learned at Chicago. Wetherill conceived of the concordia diagram, which uses the decay of radioactive uranium into lead to provide accurate dates for when the rocks crystallized. Wetherill's concordia diagram was a concept that found immediate and lasting acceptance, and stands as a singular achievement in the earth sciences. It opened up the field of geological dating for events that happened billions of years ago on the Earth and on other rocky bodies. Wetherill's great early success in geochemistry led to his being appointed as a professor of geophysics and geology at UCLA in 1960. At UCLA, Wetherill began his second major undertaking, working on the orbital evolution of asteroids and of other small bodies in the Solar System. He was the first to show that debris kicked out from meteorite impacts on Mars

  11. EAARL Topography - George Washington Birthplace National Monument 2008

    USGS Publications Warehouse

    Brock, John C.; Nayegandhi, Amar; Wright, C. Wayne; Stevens, Sara; Yates, Xan

    2009-01-01

    These remotely sensed, geographically referenced elevation measurements of Lidar-derived bare earth (BE) and first surface (FS) topography were produced as a collaborative effort between the U.S. Geological Survey (USGS), Florida Integrated Science Center (FISC), St. Petersburg, FL; the National Park Service (NPS), Northeast Coastal and Barrier Network, Kingston, RI; and the National Aeronautics and Space Administration (NASA), Wallops Flight Facility, VA. This project provides highly detailed and accurate datasets of the George Washington Birthplace National Monument in Virginia, acquired on March 26, 2008. The datasets are made available for use as a management tool to research scientists and natural resource managers. An innovative airborne Lidar instrument originally developed at the NASA Wallops Flight Facility, and known as the Experimental Advanced Airborne Research Lidar (EAARL) was used during data acquisition. The EAARL system is a raster-scanning, waveform-resolving, green-wavelength (532-nanometer) Lidar designed to map near-shore bathymetry, topography, and vegetation structure simultaneously. The EAARL sensor suite includes the raster-scanning, water-penetrating full-waveform adaptive Lidar, a down-looking red-green-blue (RGB) digital camera, a high-resolution multi-spectral color infrared (CIR) camera, two precision dual-frequency kinematic carrier-phase GPS receivers, and an integrated miniature digital inertial measurement unit, which provide for submeter georeferencing of each laser sample. The nominal EAARL platform is a twin-engine Cessna 310 aircraft, but the instrument may be deployed on a range of light aircraft. A single pilot, a Lidar operator, and a data analyst constitute the crew for most survey operations. This sensor has the potential to make significant contributions in measuring sub-aerial and submarine coastal topography within cross-environmental surveys. Elevation measurements were collected over the survey area using the EAARL

  12. Reconstitution of ST2 (IL-1R4) specific for IL-33 activity; no suppression by IL-1Ra though a common chain IL-1R3 (IL-1RAcP) shared with IL-1.

    PubMed

    Jo, Seunghyun; Kim, Eunsom; Kwak, Areum; Lee, Jungmin; Hong, Jaewoo; Lee, Jongho; Youn, Sulah; Bae, Suyoung; Kim, Busun; Ryoo, Soyoon; Kang, Tae-Bong; Her, Erk; Choi, Dong-Ki; Kim, Yong-Sung; Lee, Youngmin; Jhun, Hyunjhung; Kim, Soohyun

    2016-07-01

    Interleukin-33 (IL-33) receptors are composed of ST2 (also known as IL-1R4), a ligand binding chain, and IL-1 receptor accessory protein (IL-1RAcP, also known as IL-1R3), a signal transducing chain. IL-1R3 is a common receptor for IL-1α, and IL-1β, IL-33, and three IL-36 isoforms. A549 human lung epithelial cells are highly sensitive to IL-1α and IL-1β but not respond to IL-33. The lack of responsiveness to IL-33 is due to ST2 expression. ST2 was stably transfected into A549 cells to reconstitute its activity. RT-PCR and FACS analysis confirmed ST2 expression on the cell surface of A549/ST2 cells. Upon IL-33 stimulation, A549/ST2 cells induced IL-8 and IL-6 production in a dose dependent manner while A549/mock cells remained unresponsive. There was no difference in IL-1α and IL-1β activity in A549/ST2 cells compared to A549/mock cells despite the fact that IL-33 shares IL-1R3 with IL-1α/β. IL-33 activated inflammatory signaling molecules in a time- and dose-dependent manner. Anti-ST2 antibody and soluble recombinant ST2-Fc abolished IL-33-induced IL-6 and IL-8 production in A549/ST2 cells but the IL-1 receptor antagonist failed to block IL-33-induced cytokines. This result demonstrates for the first time the reconstitution of ST2 in A549 human lung epithelial cell line and verified its function in IL-33-mediated cytokine production and signal transduction. PMID:27031441

  13. Mt. St. Helens Memories.

    ERIC Educational Resources Information Center

    Sharp, Len

    1992-01-01

    Provides a personal account of one science teacher's participation in a teacher workshop in which teachers learned about volcanic development, types of eruption, geomorphology, plate tectonics, volcano monitoring, and hazards created by volcanoes by examining Mt. St. Helens. Provides a graphic identifying volcanoes active since 1975. (MDH)

  14. Rapid resolution of ST elevation and prediction of clinical outcome in patients undergoing thrombolysis with alteplase (recombinant tissue-type plasminogen activator): results of the Israeli Study of Early Intervention in Myocardial Infarction.

    PubMed Central

    Barbash, G I; Roth, A; Hod, H; Miller, H I; Rath, S; Har-Zahav, Y; Modan, M; Seligsohn, U; Battler, A; Kaplinsky, E

    1990-01-01

    Alteplase (recombinant tissue-type plasminogen activator (rt-PA)) was infused within four hours of onset of symptoms in 286 patients with acute myocardial infarction. Delayed coronary angiography was performed 72 hours after admission with coronary angioplasty if indicated. Electrocardiographic monitoring was continuous during the first hour of treatment. The sum of the ST segment elevations (sigma ST) was calculated on electrocardiograms recorded at entry and an hour later. ST elevations resolved rapidly within one hour of treatment in 189 patients and persisted in 97 patients. Rapid resolution of ST elevation correlated with angiographic coronary patency as determined by coronary angiography 72 hours after admission. The patients with rapid resolution of sigma ST had significantly smaller infarcts and a better clinical outcome than the patients with persistent ST elevation. sigma ST values at entry and one hour after treatment had no additional independent predictive value. Rapid resolution of ST elevations in patients undergoing thrombolysis with alteplase was associated with a significantly smaller release of creatine kinase, better preservation of left ventricular function, lower morbidity, and less short and long term mortality. Rapid resolution of sigma ST elevation is an efficient indicator of clinical outcome in groups of patients with acute myocardial infarction undergoing thrombolysis with alteplase. PMID:2121199

  15. A 21st Century Library in a 20th Century Space

    ERIC Educational Resources Information Center

    Graboyes, Alanna S.

    2012-01-01

    The library at George C. Marshall High School in Fairfax County, Virginia, needed an update to better meet the needs of 21st century students. A major renovation was in the works, but head librarian Graboyes wanted to do something to make the library useful and appealing for current students. With careful budgeting and donations of time and money,…

  16. Georges Bank: A leaky incubator of Alexandrium fundyense blooms

    NASA Astrophysics Data System (ADS)

    McGillicuddy, D. J.; Townsend, D. W.; Keafer, B. A.; Thomas, M. A.; Anderson, D. M.

    2014-05-01

    A series of oceanographic surveys on Georges Bank document variability of populations of the toxic dinoflagellate Alexandrium fundyense on time scales ranging from synoptic to seasonal to interannual. Blooms of A. fundyense on Georges Bank can reach concentrations on the order of 104 cells l-1, and are generally bank-wide in extent. Georges Bank populations of A. fundyense appear to be quasi-independent of those in the adjacent coastal Gulf of Maine, insofar as they occupy a hydrographic niche that is colder and saltier than their coastal counterparts. In contrast to coastal populations that rely on abundant resting cysts for bloom initiation, very few cysts are present in the sediments on Georges Bank. Bloom dynamics must therefore be largely controlled by the balance between growth and mortality processes, which are at present largely unknown for this population. Based on correlations between cell abundance and nutrient distributions, ammonium appears to be an important source of nitrogen for A. fundyense blooms on Georges Bank.

  17. Georges Bank: a leaky incubator of Alexandrium fundyense blooms

    PubMed Central

    McGillicuddy, D.J.; Townsend, D.W.; Keafer, B.A.; Thomas, M.A.; Anderson, D.M.

    2012-01-01

    A series of oceanographic surveys on Georges Bank document variability of populations of the toxic dinoflagellate Alexandrium fundyense on time scales ranging from synoptic to seasonal to interannual. Blooms of A. fundyense on Georges Bank can reach concentrations on the order of 104 cells l−1, and are generally bank-wide in extent. Georges Bank populations of A. fundyense appear to be quasi-independent of those in the adjacent coastal Gulf of Maine, insofar as they occupy a hydrographic niche that is colder and saltier than their coastal counterparts. In contrast to coastal populations that rely on abundant resting cysts for bloom initiation, very few cysts are present in the sediments on Georges Bank. Bloom dynamics must therefore be largely controlled by the balance between growth and mortality processes, which are at present largely unknown for this population. Based on correlations between cell abundance and nutrient distributions, ammonium appears to be an important source of nitrogen for A. fundyense blooms on Georges Bank. PMID:24976691

  18. St. Lucia.

    PubMed

    1987-06-01

    The population of St Lucia was 123,000 in 1986, with an annual growth rate of 2%. The infant mortality rate stands at 22.2/1000 live births, and life expectancy is 70.3 years for males and 74.9 years for females. The literacy rate is 78%. St Lucia's labor force is allocated as follows: agriculture, 36.6%; industry and commerce, 20.1%; and services, 18.1%. The gross national product (GNP) was US$146 million in 1985, with an annual growth rate of 3% and a per capita GNP of $1071. St Lucia is a parliamentary democracy modeled on the British Westminster system. The island is divided into 16 parishes and 1 urban area (the capital, Castries). St Lucia is currently a politically stable country, although the high level of youth unemployment is a cause for concern. Ongoing stability may depend on the government's ability to provide services such as jobs and housing. The economy has evolved from a monocrop sugar plantation type to a diversified economy based on agriculture, industry, and tourism. Agriculture, dominated by the banana industry, is characterized by the participation of a large number of small and medium-sized enterprises. Industry is being encouraged through the provision of incentives such as tax rebates. The government is attempting to maintain a sound investment climate through a tripartite dialogue with the private sector and trade unions. Overall economic policy is predicated on the attraction of sound investments, by both local and foreign entities, to accelerate the rate of economic growth, solve the unemployment problem, and generate a solid balance-of-payments position. PMID:12177918

  19. Obituary: George West Wetherill, 1925-2006

    NASA Astrophysics Data System (ADS)

    Boss, Alan Paul

    2006-12-01

    George W. Wetherill, 1997 National Medal of Science recipient, died from heart failure on 19 July 2006, at his Washington, DC home. Wetherill can be rightfully called the father of modern theories of the formation of the Earth. Prior to the first Protostars and Planets meeting in Tucson in 1978, planet formation theories tended to be eccentric concoctions created by distinguished senior scientists who had earned the right to dream a little bit about how our Solar System had formed. Wetherill was in the vanguard of the effort to place planet formation theory on a solid basis. Born in Philadelphia on 12 August 1925, Wetherill served in the U.S. Navy during World War II, teaching radar at the Naval Research Laboratory in the District. He graduated from the University of Chicago in 1953 after receiving a succession of degrees: Ph.B., S.B., S.M., and Ph.D. Wetherill joined the staff of the Carnegie Institution's Department of Terrestrial Magnetism (DTM), located in northwest Washington, DC, in 1953. He and his colleagues at DTM and Carnegie's Geophysical Laboratory proceeded to revolutionize the field of geochemical dating of rocks by applying the physics he had learned at Chicago. Wetherill conceived of the concordia diagram, which uses the decay of radioactive uranium into lead to provide accurate dates for when the rocks crystallized. Wetherill's concordia diagram was a concept that found immediate and lasting acceptance, and stands as a singular achievement in the earth sciences. It opened up the field of geological dating for events that happened billions of years ago on the Earth and on other rocky bodies. Wetherill's great early success in geochemistry led to his being appointed as a professor of geophysics and geology at UCLA in 1960. At UCLA, Wetherill began his second major undertaking, working on the orbital evolution of asteroids and of other small bodies in the Solar System. He was the first to show that debris kicked out from meteorite impacts on Mars

  20. A case of DiGeorge syndrome in Georgia.

    PubMed

    Chikovani, M; Kutubidze, T; Khvedeliani, N; Pagava, K

    2011-04-01

    Patient 6 - year- old boy, with history of recurrent otitis, cleft palate, was admitted to the hospital for fever, abdominal pain; He had high ESR,CRP, low T lymphocytes, VSD. Peritoneal fluid was positive for pseudomona aeroginoza. Diagnosis of DiGeorge syndrome was confirmed by further genetical study. Immune deficiencies should be considered when infections are severe, persistent resistant to standard treatment, or caused by opportunistic organisms. Treatments can often correct many of the critical and immediate problems associated with DiGeorge syndrome such as heart defects, calcium defects, poor immune system functions and cleft palate. People who had poor immune function as children due to small or missing thymus, may have an increased risk of autoimmune disorders, such as a rheumatoid arthritis and Graves disease. Because DiGeorge syndrome can result in so many disorders, a number of specialists should be involved in diagnosing specific conditions, recommending treatments and providing care. PMID:21617283

  1. Detecting Exoplanets with the George Mason University Telescope

    NASA Astrophysics Data System (ADS)

    Renaud, J.

    2014-04-01

    The George Mason Exoplanet Team has become an official follow up team for the KELT Survey. Research areas for the team include: Transit Timing Variations, High-altitude spectroscopy, and characterization of extrasolar planets. Detections were performed using the STX 16803 and filter wheel STX-FW7 at the George Mason 0.8m Telescope. We will present observed transit characteristics of Kelt-1b, HD189733b, WASP-33b, as well as others - discussing the transit depths, timing variations, and data reduction methods.

  2. The Role of RaxST, a Prokaryotic Sulfotransferase, and RaxABC, a Putative Type I Secretion System, in Activation of the Rice XA21-Mediated Immune Response

    PubMed Central

    Ronald, Pamela C.

    2014-01-01

    Tyrosine sulfation is an important posttranslational modification that determines the outcome of serious diseases in plants and animals. We have recently demonstrated that the plant pathogen Xanthomonas oryzae pv. oryzae (Xoo) carries a functional sulfotransferase (RaxST). raxST is required for activation of rice Xa21-mediated immunity indicating the critical, but unknown, function of raxST in mediating the Xoo/rice interaction. The raxST gene resides in the same operon (raxSTAB) as components of a predicted type I secretion and processing system (RaxA and RaxB). These observations suggest a model where RaxST sulfates a molecule that contains a leader peptide, which is cleaved by the peptidase domain of the RaxB protein and secreted outside the bacterial cell by the RaxABC T1SS. PMID:25386383

  3. "Like a Prophetic Spirit": Samuel Davies, American Eulogists, and the Deification of George Washington

    ERIC Educational Resources Information Center

    Berens, John F.

    1977-01-01

    Recounts a seeming "prophecy" made during George Washington's youth by the Reverend Samuel Davies, the prominent Presbyterian proponent of the Great Awakening. Investigates how American eulogists drew upon this "prophecy" to give validity and vitality to George Washington's legend. (MH)

  4. Interview: Mr. George Walmsley: UNFPA Country Director for the Philippines.

    PubMed

    1991-06-01

    George Walmsley, UNFPA country director for the Philippines, discusses demographic and economic conditions in the Philippines, and present plans to revitalize the national population program after 20 years of only modest achievements. The Philippines is a rapidly growing country with much poverty, unemployment and underemployment, uneven population distribution, and a large, highly dependent segment of children and youths under age 15. Initial thrusts of the population program were in favor of fertility reduction, ultimately changing to adopt a perspective more attuned to promoting overall family welfare. Concurrent with this change also came a shift from a clinic-based to community-based approach. Fertility declines have nonetheless grown weaker over the past 8-10 years. A large gap exists between family planning knowledge and practice, with contraceptive prevalence rates declining from 45% in 1986 to 36% in 1988. Behind this lackluster performance are a lack of consistent political support, discontinuities in program implementation, a lack of coordination among participating agencies, and obstacles to program implementation at the field level. The present government considers the revitalization of this program a priority concern. Mr. Walmsley discusses UNFPA's definition of a priority country, and what that means for the Philippines in terms of resources nd future activities. He further responds to questions about the expected effect of the Catholic church upon program implementation and success, non-governmental organization involvement, the role of information and information systems in the program, the relationship between population, environment and sustainable development, and the status of women and its effect on population. PMID:12343323

  5. George Jerome Magovern, MD, November 17, 1923-November 4, 2013.

    PubMed

    Magovern, George J

    2014-10-01

    George Jerome Magovern, the 20th president of The Society of Thoracic Surgeons (1984-1985) and emeritus member of the American Board of Thoracic Surgery (1984-1991), died surrounded by his family on November 4, 2013. He leaves behind him a lasting commitment to the advancement of patient care, education, and research. PMID:25282232

  6. George Peabody (1795-1869): Merchant, Banker, Philanthropist.

    ERIC Educational Resources Information Center

    Parker, Franklin; Parker, Betty J.

    This paper traces events in the life of George Peabody. Born in Danvers, Massachusetts near Boston, Peabody attended a district school for four years and was apprenticed in a general store at an early age. After four years of apprenticeship, Peabody worked with his brother in a drapery shop, then traveled to the District of Columbia with his uncle…

  7. Reputation, Canon-Formation, Pedagogy: George Orwell in the Classroom.

    ERIC Educational Resources Information Center

    Rodden, John

    1991-01-01

    Investigates the process by which books become canonized in British and U.S. schools and universities. Uses the case of George Orwell to examine the institutional and historical factors which condition the inclusion and exclusion of writer's work in Anglo-American classrooms. (SR)

  8. Vehicles to Belief: Aristotle's Enthymeme and George Campbell's Vivacity Compared.

    ERIC Educational Resources Information Center

    Roob, Andy

    The central concepts from two rhetorical systems (the enthymeme in Aristotle's rhetoric and vivacity in George Campbell's) may be understood as the connection between speech act and ascension to belief. A review of the literature indicates a gap in the scholarly works seeking to compare and contrast the periods developed by D. Ehninger's systems…

  9. 2. Historic American Buildings Survey, George W. Phillips, Photographer GENERAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey, George W. Phillips, Photographer GENERAL VIEW, PESTLE IN LOWERED POSITION (PHOTOGRAPHED IN ITS ORIGINAL LOCATION ON THE CINDY BAUMGARTNER PLACE, DEEP CREEK, N.C. BEFORE BEING REMOVED TO ITS PRESENT LOCATION). - Pounding Mill, Pioneer Museum, Route 441 (moved from Deep Creek), Cherokee, Swain County, NC

  10. 1. Historic American Buildings Survey, George W. Phillips, Photographer GENERAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey, George W. Phillips, Photographer GENERAL VIEW, PESTLE IN RAISED POSITION (PHOTOGRAPHED IN ITS ORIGINAL LOCATION ON THE CINDY BAUMGARTNER PLACE, DEEP CREEK, N.C. BEFORE BEING REMOVED TO ITS PRESENT LOCATION). - Pounding Mill, Pioneer Museum, Route 441 (moved from Deep Creek), Cherokee, Swain County, NC

  11. George Washington in a Revolutionary Era: A Larger Context.

    ERIC Educational Resources Information Center

    Arevalo, John M.

    1997-01-01

    Briefly discusses the approaches and treatment given to George Washington in most K-12 classrooms. Argues that history is more than a rote memorization of facts, and describes several programs in Texas that have attempted a broader and more consistent approach. Discusses Washington's relevance for today's students. (MJP)

  12. On Strategic Management: A Conversation with George Wilkinson.

    ERIC Educational Resources Information Center

    Brandt, Ron

    1991-01-01

    George Wilkinson, who has managed planning for United Way of America since 1980, observes that local planners using strategic planning raise more money and solve more community problems than those without such a process. Marketing is identical to strategic planning; both involve looking at an organization, doing and analysis, examining the future,…

  13. Failure of George Mason University's Persian Gulf Campus Sparks Concern

    ERIC Educational Resources Information Center

    Mills, Andrew

    2009-01-01

    Late last month, when George Mason University's campus in the Persian Gulf emirate of Ras al Khaymah became the first American educational venture in the region to collapse, its administrators immediately blamed the international economic meltdown. In a region whose higher-education scene is quickly gaining a reputation for being as hazardous as…

  14. 5. PHOTOCOPY OF MAP, L. D. FOWLER, GEORGE W. AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. PHOTOCOPY OF MAP, L. D. FOWLER, GEORGE W. AND WALTER BROMLEY, ATLAS OF JERSEY CITY, NEW JERSEY. G. W. BROMLEY AND COMPANY, PHILADELPHIA, PENNSYLVANIA, 1887. - Lembeck & Betz Eagle Brewery, 164-190 Ninth Street, 515-519 Luis Munez Marin Boulevard, Jersey City, Hudson County, NJ

  15. George Herbert's Sonnet "Prayer": A Combined Literary and Linguistic Analysis.

    ERIC Educational Resources Information Center

    Jeffcoate, Robert

    2001-01-01

    Examines George Herbert's sonnet "Prayer" to argue for the integration of literary and linguistic approaches to the critical appreciation of poetry at both A/AS and university levels of the GCSE (General Certificate of Secondary Education). Presents a model analysis of the sonnet and discusses why its distinctive linguistic and literary features…

  16. 9. AERIAL VIEW LOOKING NORTH AT THE GEORGE C. MARSHALL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. AERIAL VIEW LOOKING NORTH AT THE GEORGE C. MARSHALL SPACE FLIGHT CENTER. DODD ROAD RUNS DOWN THE CENTER OF THE PHOTO. THE EAST TEST AREA IS TOWARDS THE BOTTOM OF THE PHOTO, FABRICATION, ENGINEERING AND ADMINISTRATION NEAR THE TOP OF THE PHOTO. 1961, MSFC PHOTO LAB. - Marshall Space Flight Center, East Test Area, Dodd Road, Huntsville, Madison County, AL

  17. George Gallup and the Rhetoric of Scientific Democracy.

    ERIC Educational Resources Information Center

    Hogan, J. Michael

    1997-01-01

    Discusses George Gallup's crusade to establish polling's scientific and cultural legitimacy that mythologized its history of "progress"; deflected doubts about its accuracy and technical procedures with a rhetoric of scientific of mystification; and celebrated the collective wisdom of "the people." Shows how Gallup's "rhetoric of scientific…

  18. The Art Educator as Artist: George Szekely's New Art.

    ERIC Educational Resources Information Center

    Szekely, George

    1997-01-01

    Presents a lesson plan constructed around several color plates of the artwork of George Szekely. Szekely suggests a playful and open approach to his work and recommends various ways of interpreting and experiencing his art using a variety of senses. His recommendations include slide projectors, word games, and role playing. (MJP)

  19. Prince George's Community College Marketing Plan, 1981-1982.

    ERIC Educational Resources Information Center

    Engleberg, Isa N., Ed.; Leach, Ernest R., Ed.

    Developed by the Marketing Task Force at Prince George's Community College (PGCC) in 1981, this report presents a plan which identifies educational service needs, recommends strategies for responding to those needs, and suggests a marketing approach. The report begins by providing background on the four-stage marketing process implemented during…

  20. 36. Historic photograph, photographer unknown, c. 1943. PHOTOGRAPH OF GEORGE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. Historic photograph, photographer unknown, c. 1943. PHOTOGRAPH OF GEORGE E. SMITH (RIGHT), ONE OF THE PRINCIPAL BUILDERS OF THE VERDE RIVER SHEEP BRIDGE AND HIS SON, B. L. 'LES' SMITH. - Verde River Sheep Bridge, Spanning Verde River (Tonto National Forest), Cave Creek, Maricopa County, AZ

  1. Dr. Wernher Von Braun talkes with George Hardy.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    George Hardy of the Marshall Space Flight center's Astronautics Laboratory, talks with Dr. Wernher Von Braun (right), deputy associate administrator for planning. Dr. Von Braun was inspecting the mockup of the Saturn workshop during a visit to the Marshall Center. The visit coincided with the 10th anniversary celebration of the center of which Dr. Von Braun was director until March 1, 1970.

  2. 262. SENIOR OFFICER'S QUARTERS A, 194041. GEORGE A FULLER AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    262. SENIOR OFFICER'S QUARTERS A, 1940-41. GEORGE A FULLER AND CO., DESIGNERS OF THE REWORKING OF A C. 1939 SUMMER COTTAGE INTO THIS NEOCOLONIAL RESIDENCE--THE LARGEST AND FOCAL ELEMENT IN THE SENIOR OFFICERS HOUSING AREA. VIEW FROM THE WEST SHOWING THE ENTRANCE ELEVATION OF QUARTERS A. - Quonset Point Naval Air Station, Roger Williams Way, North Kingstown, Washington County, RI

  3. The Rhetoric of the Challenger: George Stanley McGovern.

    ERIC Educational Resources Information Center

    Trent, Judith S.; Trent, Jimmie D.

    Reasons for George McGovern's presidential election failure are summarized in the context of McGovern's rhetoric as a challenger. Taking the point of view that McGovern abandoned the traditional rhetorical advantages of the challenger, the authors conclude that this abandonment along with the problems of financing, the impression of alignment with…

  4. George Washington Community High School: Analysis of a Partnership Network

    ERIC Educational Resources Information Center

    Bringle, Robert G.; Officer, Starla D. H.; Grim, Jim; Hatcher, Julie A.

    2009-01-01

    After five years with no public schools in their community, residents and neighborhood organizations of the Near Westside of Indianapolis advocated for the opening of George Washington Community High School (GWCHS). As a neighborhood in close proximity to the campus of Indiana University-Purdue University Indianapolis, the Near Westside and campus…

  5. 29. ORE DOCK, LOOKING WEST; AT WORK UNLOADING THE 'GEORGE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    29. ORE DOCK, LOOKING WEST; AT WORK UNLOADING THE 'GEORGE M. HUMPHREY'S' CARGO OF 25,000. TONS OF ORE. - Pennsylvania Railway Ore Dock, Lake Erie at Whiskey Island, approximately 1.5 miles west of Public Square, Cleveland, Cuyahoga County, OH

  6. George Herbert Mead's Contribution to the Philosophy of American Education.

    ERIC Educational Resources Information Center

    Renger, Paul, III

    1980-01-01

    George Herbert Mead's general philsophy showed that he regarded the development of distinctively human behavior as essentially the result of an individual's meaningful participation in the social process of the community to which he belongs. Mead believed that education was a social process involving the meaningful interaction and communication…

  7. George F. Root's Normal Musical Institute, 1853-1885

    ERIC Educational Resources Information Center

    Hash, Phillip M.

    2012-01-01

    George F. Root, Lowell Mason, and William B. Bradbury opened the New York Normal Musical Institute in April of 1853 in New York City. Each term lasted about three months and provided the first long-term preparation program for singing-school masters, church choir directors, private instructors, and school music teachers in the United States.…

  8. George Pierce Baker's "Principles of Argumentation": "Completely Logical"?

    ERIC Educational Resources Information Center

    Bordelon, Suzanne

    2006-01-01

    The article contends that previous scholars have misread George Pierce Baker's efforts by focusing primarily on "The Principles of Argumentation" and the role of logic. Baker's view of logic was more complex than scholars have claimed. He challenged traditional concepts of formal logic, highlighting only those aspects that would help students…

  9. The George Wallace Shooting: News Diffusion and the Sleeper Effect.

    ERIC Educational Resources Information Center

    Steinfatt, Thomas M.; And Others

    Previous studies conclude that the assassination attempt on George C. Wallace was a news event of high, but not maximum, importance, implying that the majority of respondents in any sample would report first learning of the attack via mass media sources. The authors interviewed 144 persons in Ann Arbor, Michigan, regarding their awareness of the…

  10. 33 CFR 334.520 - Lake George, Fla.; naval bombing area.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Lake George, Fla.; naval bombing... ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.520 Lake George, Fla.; naval bombing area. (a) The danger zone. An area in the eastern part of Lake George described as...

  11. 33 CFR 334.520 - Lake George, Fla.; naval bombing area.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Lake George, Fla.; naval bombing... ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.520 Lake George, Fla.; naval bombing area. (a) The danger zone. An area in the eastern part of Lake George described as...

  12. 33 CFR 334.520 - Lake George, Fla.; naval bombing area.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Lake George, Fla.; naval bombing... ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.520 Lake George, Fla.; naval bombing area. (a) The danger zone. An area in the eastern part of Lake George described as...

  13. 33 CFR 334.520 - Lake George, Fla.; naval bombing area.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Lake George, Fla.; naval bombing... ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.520 Lake George, Fla.; naval bombing area. (a) The danger zone. An area in the eastern part of Lake George described as...

  14. 33 CFR 334.520 - Lake George, Fla.; naval bombing area.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Lake George, Fla.; naval bombing... ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.520 Lake George, Fla.; naval bombing area. (a) The danger zone. An area in the eastern part of Lake George described as...

  15. George Sudarshan, No-Go theorems and the exclusion principle

    NASA Astrophysics Data System (ADS)

    Han, M. Y.

    2009-11-01

    We review two areas of my work that were directly and indirectly initiated and inspired by George. One is the proofs of no-go theorems in combining the spacetime and internal symmetries in non-trivial ways and the other is how Georges firm conviction on the fundamentality of the spin-statistics theorem helped to expand the domain of applicability of the spin-statistics theorem into the arena of quarks and gluons, going far beyond the original application of the exclusion principle in atomic physics. In order to provide deeper understanding of mass differences of particles belonging to spin-degenerate multiplets, attempts have been made to see if some non-trivial way of embedding the Lorentz group and internal symmetry groups such as SU(2) and SU(3) into a larger group. When a hint of no-go theorem (that such non-trivial embedding cannot be achieved) first appeared, George went to work and led many of us, including myself, into this area of research. A series of proofs of no-go theorems by George, myself and others eventually led to the definitive proof by Lochlainn O'Raifeartaigh that came to be known as the ORaifeartaigh theorem. Lochlainn also joined George at Syracuse at the same time I went there. The second area in which George had significant influence on my work is his fervent belief in the fundamental importance of the spin-statistics relationship. First postulated by Worlfgang Pauli to explain the periodic table of elements, the relationship the exclusion principle has exceeded far beyond its original domain of validity. The relationship has been upheld across the scale molecular, atomic, and nuclear structures. What is less known is the fact the relationship continues to remain valid in scales smaller than nucleons. The spin-statistics relationship was one of the compelling reasons for Nambu and I to introduce a new set of then undiscovered degrees freedom for quarks inside nucleons. This new degrees of freedom came to be called the color charges of

  16. 78 FR 63380 - Amendment of Class E Airspace; St. George, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ... FR 45473). Interested parties were invited to participate in this rulemaking effort by submitting... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in 14 CFR...

  17. Antiulcerogenic Activity of the Hydroalcoholic Extract of Leaves of Croton campestris A. St.-Hill in Rodents

    PubMed Central

    Júnior, Francisco E. B.; de Oliveira, Dayanne R.; Bento, Elizângela B.; Leite, Laura H. I.; Souza, Daniele O.; Siebra, Ana Luiza A.; Sampaio, Renata S.; Martins, Anita O. P. B.; Ramos, Andreza G. B.; Tintino, Saulo R.; Lacerda-Neto, Luiz J.; Figueiredo, Patricia R. L.; Oliveira, Larissa R.; Rodrigues, Cristina K. S.; Sales, Valterlúcio S.; Figueiredo, Francisco R. S. D. N.; Nascimento, Emmily P.; Monteiro, Alefe B.; Amaro, Érika N.; Costa, José G. M.; Douglas Melo Coutinho, Henrique; de Menezes, Irwin R. A.; Kerntopf, Marta R.

    2013-01-01

    Croton campestris A. St.-Hill., popularly known as “velame do campo,” is a species native to the savannah area of Northeast Brazil, which is used by traditional communities in folk medicine for variety of health problems, especially detoxification, inflammation, and gastritis. The hydroalcoholic extract of C. campestris leaves (HELCC) was assessed for its antiulcerogenic effect in gastric lesion models and effect on intestinal motility in mice, and possible mechanisms of action were examined. HELCC showed significant gastroprotective action in all models of gastric ulcer evaluated; the results suggest that this action probably involves the nitric oxide pathway. HELCC did not show alteration of intestinal motility in mice. It was also found that C. campestris represents a promising natural source with important biological potential, justifying some of its uses in folk medicine. PMID:23864894

  18. Revision Surgery in Permanent Patellar Dislocation in DiGeorge Syndrome

    PubMed Central

    Berruto, Massimo; Parente, Andrea; Ferrua, Paolo; Pasqualotto, Stefano; Uboldi, Francesco; Usellini, Eva

    2015-01-01

    A 29-year-old patient, suffering from DiGeorge syndrome, came to our attention with a history of persistent pain and patellar instability in the left knee after failure of arthroscopic lateral release and Elmslie-Trillat procedure. The patient was unable to walk without crutches and severely limited in daily living activities. Because of arthritic changes of the patellofemoral joint and the failure of previous surgeries it was decided to perform only an open lateral release and medial patellofemoral ligament (MPFL) reconstruction using a biosynthetic ligament in order to obtain patellofemoral stability. At one year post-op range of motion (ROM) was 0–120 with a firm end point at medial patellar mobilization; patella was stable throughout the entire ROM. All the scores improved and she could be able to perform daily activity without sensation of instability. Bilateral patellar subluxation and systemic hyperlaxity are characteristics of syndromic patients and according to literature can be also present in DiGeorge syndrome. MPFL reconstruction with lateral release was demonstrated to be the correct solution in the treatment of patellar instability in this complex case. The choice of an artificial ligament to reconstruct the MPFL was useful in this specific patient with important tissue laxity due to her congenital syndrome. PMID:26783479

  19. The ppuI-rsaL-ppuR quorum-sensing system regulates cellular motility, pectate lyase activity, and virulence in potato opportunistic pathogen Pseudomonas sp. StFLB209.

    PubMed

    Kato, Taro; Morohoshi, Tomohiro; Someya, Nobutaka; Ikeda, Tsukasa

    2015-01-01

    Pseudomonas sp. StFLB209 was isolated from potato leaf as an N-acylhomoserine lactone (AHL)-producing bacterium and showed a close phylogenetic relationship with P. cichorii, a known plant pathogen. Although there are no reports of potato disease caused by pseudomonads in Japan, StFLB209 was pathogenic to potato leaf. In this study, we reveal the complete genome sequence of StFLB209, and show that the strain possesses a ppuI-rsaL-ppuR quorum-sensing system, the sequence of which shares a high similarity with that of Pseudomonas putida. Disruption of ppuI results in a loss of AHL production as well as remarkable reduction in motility. StFLB209 possesses strong pectate lyase activity and causes maceration on potato tuber and leaf, which was slightly reduced in the ppuI mutant. These results suggest that the quorum-sensing system is well conserved between StFLB209 and P. putida and that the system is essential for motility, full pectate lyase activity, and virulence in StFLB209. PMID:25485871

  20. Thymus Transplantation in Complete DiGeorge Anomaly

    PubMed Central

    Markert, M. Louise; Devlin, Blythe H.; Chinn, Ivan; McCarthy, Elizabeth A.

    2016-01-01

    Complete DiGeorge anomaly is characterized by athymia, congenital heart disease and hypoparathyroidism. This congenital disease is fatal by age 2 years unless immune reconstitution is successful. There are multiple underlying syndromes associated with complete DiGeorge anomaly including 22q11 hemizygosity in approximately 50%, CHARGE association in approximately 25%, and diabetic embryopathy in approximately 15%. Approximately one third of patients present with rash and lymphadenopathy associated with oligoclonal “host” T cells. This condition resembles Omenn syndrome. Immunosuppression is necessary to control the oligoclonal T cells. The results of thymus transplantation are reported for a series of 50 patients, 36 of whom survive. The survivors develop naïve T cells and a diverse T cell repertoire. PMID:19066739

  1. 7. View of interior of Lock No. 2 on George ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. View of interior of Lock No. 2 on George washington 'Potowmack' Canal at Great Falls, Virginia. This lock is about 15 ft. in depth and possibly 70 or 60 ft. in length. Some 15 or 20 years ago, when a restoration was crudely attempted, the old oaken flooring, which was invariably placed at the bottom of canal locks, was roughly torn up and destroyed. The trunks and stumps of gigantic trees still remain from this restorative effort, and their girth indicates again the antiquity of this evidence of George Washington's work as an engineer. The stones are of the red Seneca type and were evidently ferried from the Maryland side above the dam and then brought by sled or rollers to this location. These stones were beautifully hand-cut and fitted with ... - Potowmack Company: Great Falls Canal, Lock No. 2, Great Falls, Fairfax County, VA

  2. Gravity measurements in the vicinity of Georges Bank

    USGS Publications Warehouse

    Hendricks, John D.; Robb, James D.

    1973-01-01

    A total of 97 new bottom gravity measurements on the continental shelf in the vicinity of Georges Bank was reduced to the simple Bouguer anomaly, using a density of 2.80 gm per cm3 for the correction. Results help substantiate the presence of mafic and felsic intrusive bodies along the northern edge of the bank. A gravity low near the center of the bank, trending northeast, corresponds to the Georges Bank trough. An abrupt change in the gravity gradient near the southeast edge of the bank probably represents the thinning of the crust from continental to oceanic thicknesses. Differences in gravity gradient support the suggestion of a fault along the northern edge of the bank.

  3. 1. GENERAL VIEW. Statues: Maj. Gen George Meade by Daniel ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. GENERAL VIEW. Statues: Maj. Gen George Meade by Daniel Chester French, south side; Maj. Gen. John Reynolds by Charles Grafly, north side. Equestrian Statues: Maj. Gen George B. McClellan by Edward C. Potter, south side; Maj. Gen Winfield S. Hancock by J.Q.A. Ward, north side. The statue at the base of northern inner pedestal is Richard Smith, a type founder and donor of the Memorial. The niches are filled with eight colossal busts including Union generals, admirals, Pennsylvania governor, Memorial's architects (John T. and James H. Windrim), and executor of Smith's will. The frieze is carved with the names of eighty-four prominent Pennsylvania participants in the Civil War. - Smith Memorial Arch, Philadelphia, Philadelphia County, PA

  4. UF6 overfilling prevention at Eurodif production Georges Besse plant

    SciTech Connect

    Reneaud, J.M.

    1991-12-31

    Risk of overfilling exists on different equipments of Georges BESSE Plant: cylinders, desublimers and intermediate tanks. The preventive measures are composed of technical devices: desublimers weighing, load monitoring alarms, automatic controls ... and procedures, training, safety organization. In thirteen years of operation, some incidents have occurred but none of them has caused any personal injuries. They are related and discussed. The main factors involved in the Sequoyah fuel facility accident on 1/4/1986 have been analyzed and taken into account.

  5. Rheticus [Rhaeticus; Lauchen, Georg Joachim von] (1514-74)

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    Born in Feldkirch, Austria, and started an extraordinary life with the name Georg Iserin. After his father was executed for sorcery and his name was abandoned, Iserin took a germanized form of his mother's maiden name and then the name of Rheticus (the Roman name of the province where he had been born). Taught mathematics and astronomy at the University of Wittenberg, visited COPERNICUS for two y...

  6. Dr. Hugh Dryden Swearing in Dr. George E. Mueller

    NASA Technical Reports Server (NTRS)

    1963-01-01

    Dr. George E. Mueller being sworn in, as Associate Administrator for the Office of Manned Space Flight for NASA, by Dr. Hugh L. Dryden NASAs Deputy Administrator. The ceremony took place at NASA HQ in Washington, DC on September 3, 1963. Mueller served as Associate Administrator from 1963 to 1969, where he was responsible for overseeing the completion of Project Apollo and for beginning the development of the Space Shuttle.

  7. DiGeorge syndrome with vertebral and rib dysplasia

    SciTech Connect

    Puno-Cocuzza, C.; David, K.; Kogekar, N.

    1994-09-01

    DiGeorge syndrome results from defect in the development of the third and fourth pharyngeal pouches, and is characterized by conotruncal heart defects, aplasia or hypoplasia of thymus and parathyroid glands resulting in immune deficiency and hypocalcemia. Other associated abnormalities include renal, thyroid and diaphragmatic defects, oral clefting, etc. Etiologically, it is heterogeneous, with a microdeletion of 22q11 present in over 80% of cases. Our patient was born following a pregnancy complicated by insulin dependent gestational diabetes. There was truncus arteriosus type 2, absense of thymic shadow on CXR with severe deficiency of T cell function, and persistent hypocalcemia with low parathormone. Right kidney was absent. Dysplastic ribs including fused and bifid ribs were noted. Hypoplastic vertebrae and hemivertebrae were present through thoracic and lumbar regions. Chromosome analysis was normal, and metaphase FISH analysis with probe N25 representing locus D22S75 did not show any deletion of 22q11.2. The skeletal findings similar to these have not been previously reported in association with DiGeorge syndrome to our knowledge. Vertebral and rib abnormalities are known to occur with pregestational maternal diabetes. Maternal diabetes has also been suggested to be a possible etiology in a very small proportion of DiGeorge syndrome cases. It is possible that these findings occured together on account of gestational maternal diabetes in our case.

  8. Obituary: George Hamilton Bowen Jr. (1925-2009)

    NASA Astrophysics Data System (ADS)

    Willson, Lee Anne; Struck, Curtis

    2011-12-01

    Our colleague and collaborator George Hamilton Bowen, Jr., passed away November 1, 2009 in Ames, Iowa. George was born June 20, 1925 in Tulsa, Oklahoma to George and Dorothy (Huntington) Bowen. He married Marjorie Brown June 19, 1948 in Redondo Beach, California; they had five children, with eight grandchildren and five great-grandchildren at the time of his death. George H. Bowen's third or perhaps his fourth career was in astronomy. He was drafted into the navy in 1944, at the end of his first year as a student at Caltech, and ended his war-time service as an electronic technician on the aircraft carrier Shangri-La. He later said "In just nine months, starting from scratch (Ohm's law!), we learned an amazing amount - not by memorization, of course, but by study and real understanding of the basic function of the most advanced AC circuits then being used for instrumentation, measurements, communications, control systems, and much more." He gained a confidence that he could quickly and accurately diagnose and solve technical problems that stood him well in future work. One accomplishment he took particular pride in was figuring out how the radar control used cams and gears to solve the trigonometry for accurate pointing. He also described how the captain was alarmed when weather conditions changed so that refraction no longer showed them distant, small boats around the curvature of Earth. After the war, George Bowen returned to undergraduate and eventually graduate study at Caltech, where he was recruited to the biophysics research group headed by future Nobel Laureate Max Delbrück. George often described his joy in working with these first-rate scientists and finding himself accepted as a part of the effort. He finished his BS with honors in 1949 and his PhD in 1953 with a thesis on "Kinetic Studies on the Mechanism of Photoreactivation of Bacteriophase T2 Inactivated by Ultraviolet Light" involving work with E Coli. This work was supported by grants from the U

  9. Climate Controlled Sedimentation in Maxwell Bay, King George Island, Antarctica

    NASA Astrophysics Data System (ADS)

    Hass, H.; Kuhn, G.; Wittenberg, N.; Woelfl, A.; Betzler, C.

    2012-12-01

    Climatic change in Antarctica is strongest over the Antarctic Peninsula where in places the annual mean temperatures increased by 0.5 K per decade through the past 60 years. The impact of this warming trend is clearly visible in the form of retreating glaciers and melting ice sheets, loss of sea ice and strong meltwater discharge into the coastal zone. While it is generally accepted that the rapidity of the present climate change bears a significant anthropogenic aspect, it is not clear whether the effects caused by the warming trend are exceptional and unprecedented or whether the reaction of the environment is similar to that of earlier climate phases such as the Medieval Warm Period (MWP) about 1,000 years ago. One of the major goals of the joint international research project IMCOAST is to investigate the strength of the recent warming trend and its impact on the marine environment of the West Antarctic Peninsula (WAP). The study we present here reveals the Upper Holocene climatic history based on high-resolution sediment cores from Maxwell Bay (King George Island, WAP) and information on the actual processes triggered or altered by the recent warming trend based on sedimentologic and hydroacoustic investigations in Potter Cove, a tributary fjord to Maxwell Bay. Long sediment cores from Maxwell Bay reveal grain-size changes that can be linked to cold and warm phases such as the Little Ice Age (LIA) and the MWP. Generally, warm phases are finer grained than cold phases as a result of longer and stronger melting processes during the warm phases. It is suggested that meltwater plumes carry fine-grained sediment out of the surrounding fjords into Maxwell Bay where it settles in suitable areas to produce sediments that have a modal value around 16 μm. This mode is largely absent in sediments deposited during e.g. the LIA. However, post LIA sediments are depleted in the 16 μm-mode sediment suggesting slightly different conditions during the last century. One reason

  10. [Georges Schaltenbrand (26. 11. 1897 24. 10. 1979)].

    PubMed

    Collmann, Hartmut

    2008-01-01

    Georges Schaltenbrand was one of the most prodigious and internationally renowned neurologists in post war Germany. Trained by Max Nonne in Hamburg, he early gained international experience during stays in The Netherlands, the United States, and China. In 1935 quarrels with Nazi representatives forced him to go to Würzburg, where he built an own neurological service. This unit subsequently grew up to an internationally recognized center. Schaltenbrand scientifically contributed to the organization and diagnostics of the motor system, to the physiology and pathology of the cerebrospinal fluid system, and to multiple sclerosis. His textbook and atlas on stereotaxy, authored with his American friend Percival Bailey in 1959, remained a standard reference in stereotactic surgery until recent years. Only late after his death his unethical scientific activities during wartime came to common public knowledge. In an attempt to confirm his hypothesis of an infectious aetiology of multiple sclerosis, he had inoculated mentally handicapped and other severely ill patients with cerebrospinal fluid of apes putatively suffering from multiple sclerosis and also of patients with verified multiple sclerosis. He explicitly accepted the risk of causing some morbidity and even mortality in his study persons. He published his experiments in several articles and oral presentations since 1940, and, comprehensively, in a monograph 1943. Although commented as early as 1949, his dubious studies were widely ignored until a critical review appeared in an American journal in 1994. Since then, the studies are frequently cited as a typical example of Nazi medical science. However, with due regard to the historical background and the personality of Schaltenbrand his experiments should rather be brought into line with a worldwide practice at that time of using patients as study objects without asking for their consent. As a response to this practice several laws had been adopted, beginning in 1900

  11. Wastewater characterization survey, Victor Valley Wastewater Reclamation Authority and hazardous-waste survey at George AFB, California. Final report

    SciTech Connect

    Binovi, R.D.; Ng, E.K.; Tetla, R.A.

    1987-01-01

    This is a report of a survey of the Victor Wastewater Reclamation Authority Sewerage system, the sewage treatment plant, and effluent from the various operations at George AFB, California. The scope of work included the characterization of the wastewater from George AFB, as well as characterization of effluents from 29 oil/water separators servicing industrial operations on base, flow measurements at three locations on base, a microbiological evaluation of aeration basin foam, bench-scale activated-sludge studies, and a review of results from previous surveys. Recommendations: (1) AFFF (Aqueous Film Forming Foam) should never be discharged to the sewer. (2) Programming for pretreatment should proceed at selected operations. (3) More waste and wastestream analysis be performed. (4) Upgrade waste accumulation points. (5) Implement an aggressive inspection program for oil/water separators. (6) Cut down on nonessential washing.

  12. Using Satellite Data to Characterize the Temporal Thermal Behavior of an Active Volcano: Mount St. Helens, WA

    NASA Technical Reports Server (NTRS)

    Vaughan, R. Greg; Hook, Simon J.

    2006-01-01

    ASTER thermal infrared data over Mt. St Helens were used to characterize its thermal behavior from Jun 2000 to Feb 2006. Prior to the Oct 2004 eruption, the average crater temperature varied seasonally between -12 and 6 C. After the eruption, maximum single-pixel temperature increased from 10 C (Oct 2004) to 96 C (Aug 2005), then showed a decrease to Feb 2006. The initial increase in temperature was correlated with dome morphology and growth rate and the subsequent decrease was interpreted to relate to both seasonal trends and a decreased growth rate/increased cooling rate, possibly suggesting a significant change in the volcanic system. A single-pixel ASTER thermal anomaly first appeared on Oct 1, 2004, eleven hours after the first eruption - 10 days before new lava was exposed at the surface. By contrast, an automated algorithm for detecting thermal anomalies in MODIS data did not trigger an alert until Dec 18. However, a single-pixel thermal anomaly first appeared in MODIS channel 23 (4 um) on Oct 13, 12 days after the first eruption - 2 days after lava was exposed. The earlier thermal anomaly detected with ASTER data is attributed to the higher spatial resolution (90 m) compared with MODIS (1 m) and the earlier visual observation of anomalous pixels compared to the automated detection method suggests that local spatial statistics and background radiance data could improve automated detection methods.

  13. Social Reconstructionist Philosophy of Education and George S. Counts: Observations on the Ideology of Indoctrination in Socio-Critical Educational Thinking

    ERIC Educational Resources Information Center

    Sutinen, Ari

    2014-01-01

    This article comprises three parts: The author first outlines the principles of the social reconstructionist philosophy of education related to educational activity and social philosophy. After this, he describes the educational philosophy of George S. Counts, the most important developer of the social reconstructionist philosophy of education,…

  14. The least known participant in the Gotha meeting in 1798: George Butler

    NASA Astrophysics Data System (ADS)

    Dick, Wolfgang R.; Brosche, Peter; Gerdes, Dieter

    In a letter to Schedius Zach mentioned a certain ``Nuttler from Cambridge'' as one of the participants in the first astronomical meeting held in Gotha in 1798, but up to now nothing was known about this person. There is now evidence that George Butler (1774-1853), then a young fellow of Sidney Sussex College, Cambridge, participated in the meeting. Butler gratuated M.A. in 1797 and took his B.D. and D.D. in 1804 and 1805. He is reported to have spoken German, French and Italian with correctness and fluency. In the summer of 1798 he went on a tour of the Continent, visiting primarily the German-speaking territories. On September 9 Butler visited Georg Christoph Lichtenberg in Göttingen, and on September 19 he arrived in Weimar, where he met Goethe, Herder and others. Possibly he came to Göttingen from Gotha, where the astronomical meeting lasted until the end of August. Butler, later Headmaster of Harrow School and Dean of Peterborough, was elected FRS on May 20, 1819. He became an original member of the Royal Astronomical Society during its first ``proper'' meeting on February 8, 1820. Butler had great mathematical attainments and was practically versed in chemistry and other branches of physical science. Seemingly he was not very active in astronomy.

  15. Family life and human development (sex education): the Prince George's County Public Schools experience.

    PubMed

    Schaffer, M J

    1981-04-01

    The Family Life and Human Development (Sex Education) program is now fully implemented in 99.5% of Prince George's County Public Schools. The program is credited with better than 98% parental acceptance and student participation. The administrative guidelines and program supervision are crucial to the program's success. The program was developed to be in compliance with the Maryland State Board of Education Bylaw 13.03.03.01 that requires that sex education be offered. Prior to program implementation, the guidelines were written, parents were involved, and teachers and administrators were trained. All instruction is organized around 3 areas of focus: interpersonal relationships; physiological and personality changes of puberty; and advanced physiology and psychology of human sexual behavior. The major limitation of the program is that in grades 9-12 when such subjects as contraception, abortion, homosexuality and premarital intercourse can be discussed, only a small percentage of the student population are able to enroll each year. The reason for the low percentage include lack of funds to hire additional teachers, limited time due to 1/2 day work/study teachers, and the elective classification of the program. Before a teacher is permitted to teach any aspect of the program that deals with the reproductive system or any potentially sensitive area of sexuality, he/she must 1st meet certain established criteria. PMID:6908929

  16. The first direct human blood transfusion: the forgotten legacy of George W. Crile.

    PubMed

    Nathoo, Narendra; Lautzenheiser, Frederick K; Barnett, Gene H

    2009-03-01

    GEORGE W. CRILE is best known as the father of physiological surgery in the United States, a pioneer surgeon, an innovator and inventor, a founding member of the American College of Surgeons, and the principal founder of the Cleveland Clinic Foundation. However, Crile's legacy of performing the first direct blood transfusion in humans has been all but forgotten, even though the results were published in the leading scientific journals of the day. Crile's lifelong interest in the treatment of surgical shock led to his interest in blood transfusion. A chance visit to the laboratory of Alexis Carrel in 1902 resulted in Crile perfecting his technique for direct blood transfusion. He subsequently modified Carrel's anastomosis technique to administer a faster transfusion, investigated the use of blood transfusions in various clinical settings, and went on to introduce the concept and technique of blood transfusion to soldiers during World War I. In this report, we trace his long-time interest in blood transfusion and document the events that led to the first successful blood transfusion performed between 2 brothers on August 6, 1906, at St. Alexis Hospital, Cleveland, OH. PMID:19240569

  17. Diel activity patterns of major species of adult mosquitoes and ULV spraying impacts in St. John's County, Florida

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Knowledge of daily activity patterns in adult mosquitoes can be used to determine the best time to apply adulticides for mosquito control. Many factors influence these activity patterns, including migration, hormonal cycles in the mosquito, hunger, and the need to lay eggs. In this study, FL scien...

  18. St. Louis Area Earthquake Hazards Mapping Project

    USGS Publications Warehouse

    Williams, Robert A.; Steckel, Phyllis; Schweig, Eugene

    2007-01-01

    St. Louis has experienced minor earthquake damage at least 12 times in the past 200 years. Because of this history and its proximity to known active earthquake zones, the St. Louis Area Earthquake Hazards Mapping Project will produce digital maps that show variability of earthquake hazards in the St. Louis area. The maps will be available free via the internet. They can be customized by the user to show specific areas of interest, such as neighborhoods or transportation routes.

  19. Continuous monitoring of Mount St. Helens Volcano

    USGS Publications Warehouse

    Spall, H.

    1980-01-01

    Day by day monitoring of the Mount St. Helens Volcano. These are four scenarios, very different scenarios, that can occur in a average week at Mount St. Helens. Ranging from eruptions of gas and to steam to eruptions of ash and pyroclastic flows to even calm days. This example of monitoring illustrates the differences from day to day volcanic activities at Mount St. Helens. 

  20. Obituary: George Hamilton Bowen Jr. (1925-2009)

    NASA Astrophysics Data System (ADS)

    Willson, Lee Anne; Struck, Curtis

    2011-12-01

    Our colleague and collaborator George Hamilton Bowen, Jr., passed away November 1, 2009 in Ames, Iowa. George was born June 20, 1925 in Tulsa, Oklahoma to George and Dorothy (Huntington) Bowen. He married Marjorie Brown June 19, 1948 in Redondo Beach, California; they had five children, with eight grandchildren and five great-grandchildren at the time of his death. George H. Bowen's third or perhaps his fourth career was in astronomy. He was drafted into the navy in 1944, at the end of his first year as a student at Caltech, and ended his war-time service as an electronic technician on the aircraft carrier Shangri-La. He later said "In just nine months, starting from scratch (Ohm's law!), we learned an amazing amount - not by memorization, of course, but by study and real understanding of the basic function of the most advanced AC circuits then being used for instrumentation, measurements, communications, control systems, and much more." He gained a confidence that he could quickly and accurately diagnose and solve technical problems that stood him well in future work. One accomplishment he took particular pride in was figuring out how the radar control used cams and gears to solve the trigonometry for accurate pointing. He also described how the captain was alarmed when weather conditions changed so that refraction no longer showed them distant, small boats around the curvature of Earth. After the war, George Bowen returned to undergraduate and eventually graduate study at Caltech, where he was recruited to the biophysics research group headed by future Nobel Laureate Max Delbrück. George often described his joy in working with these first-rate scientists and finding himself accepted as a part of the effort. He finished his BS with honors in 1949 and his PhD in 1953 with a thesis on "Kinetic Studies on the Mechanism of Photoreactivation of Bacteriophase T2 Inactivated by Ultraviolet Light" involving work with E Coli. This work was supported by grants from the U

  1. [Talking or doing? Gender differences in physical activity participation in Israel at the threshold of the 21st century].

    PubMed

    Chachashvili-Bololotin, Svetlana; Lissitsa, Sabina; Galily, Yair

    2010-06-01

    The absence of physical activity is an important factor affecting illness, mortality and high costs of medical treatment in the western world. The advances in technology in the last couple of decades led to a more passive lifestyle, thereby affecting population health. Although the number of Israelis declaring regular participation in physical activity is rising, their numbers are lower in comparison to percentages in the western world. The aim of the present research is to assist in planning an incentive policy towards physical activity at leisure by mapping the popularity of this activity among an adult Jewish population both by participation and attitudes towards the subject. Data were collected in 2007 as part of the International Social Survey Program (ISSP) involving face-to-face interviews. In the current sample of 18 year olds and older, 1032 interviewees were divided into groups by cluster analysis. Findings suggest that we can not relate to the population as a whole, but rather, to four different types: A. Sport in the soul--pro-sport as well as active in physical activity. B. Anti-sport--holds a negative standpoint towards sport and not active physically. C. Armchair sportsman--Holds a positive attitude towards sport, however they are not active and D. Sports as fashion--an active person who holds a neutral or negative attitude towards sport. While attempting to characterize the types by gender, the study suggests that women tend to be part of the Anti-Sport and Sports as fashion, unlike men who tend to be part of the Sport in the soul and Armchair sportsman groups. Furthermore, differences were more highly related to standpoints rather than behavior. Men hold more positive attitudes towards sport than women who participate in physical activity for instrumental reasons. Such differences can be explained by gender differences in socialization in sport. If such instrumental needs will be fulfilled by alternative means, women might reduce or will even

  2. Social Movements Against Racist Police Brutality and Department of Justice Intervention in Prince George's County, Maryland.

    PubMed

    Hutto, Jonathan W; Green, Rodney D

    2016-04-01

    Racist police brutality has been systemic in Prince George's County, Maryland. The victims include African Americans, the mentally challenged, and immigrant populations, creating a complex and uneven public health impact. Three threads characterize the social movements and intervention since 1970. First, a significant demographic shift occurred as African Americans became the majority population in the late 1980s when the first Black county executive was elected in 1994. Despite the change in political leadership, police brutality remained rampant. Lower-income households located close to the District of Columbia and "inside the beltway" experienced the most police brutality. In 2001, The Washington Post revealed that between 1990 and 2000, Prince George's police shot and killed more citizens per officer than any of the 50 largest city and county law enforcement agencies in the country, 84 % of whom were black. Of the 147 persons shot during the 1990s, 12 were mentally and/or emotionally disturbed; 6 of these shootings were fatal. Second, resistance to police brutality emerged in a variety of political formations throughout the period, especially in the late 1990s. Sustained community pressure prompted the Department of Justice (DOJ) to open a civil rights investigation of the police department in November 2000. To avoid a potential federal lawsuit, the county leadership negotiated a memorandum of agreement (MOA) with the DOJ to enact policy reforms, part of which called for supplementing the departmental mobile crisis team, comprised of mental health care professionals, to respond to all cases involving mentally challenged citizens. Third, the incomplete process of change subsequent to the ending of DOJ oversight suggests a continued challenge to social movements opposing police brutality. This study focuses on the effectiveness of the MOA along with the activism of the People's Coalition for Police Accountability (PCPA) in reforming a culture of police brutality

  3. Tuberculosis, bronchiectasis, and infertility: what ailed George Orwell?

    PubMed

    Ross, John J

    2005-12-01

    In the last and most productive years of his life, George Orwell struggled with pulmonary tuberculosis, dying at the dawn of the era of chemotherapy. His case history illustrates clinical aspects of tuberculosis with contemporary relevance: the role of poverty in its spread, the limited efficacy of monotherapy, the potential toxicity of treatment, and the prominence of cachexia as a terminal symptom. Orwell's ordeals with collapse therapy may have influenced the portrayal of the tortures of Winston Smith in the novel 1984. I discuss unifying diagnoses for Orwell's respiratory problems and apparent infertility, including tuberculous epididymitis, Young syndrome, immotile cilia syndrome, and cystic fibrosis. PMID:16267732

  4. Georg von Békésy: visualization of hearing.

    PubMed

    Evans, Rand B

    2003-09-01

    Georg von Békésy received the Nobel Prize in 1961 for his research on the functioning of the auditory system. In psychoacoustics, Békésy both extended and perfected the lines of research begun by von Helmholtz in the 19th century. First in his native Hungary and later at Harvard, Békésy used novel and imaginative devices and methods to observe and model the functioning of the inner ear. He also explored the nature of sensory inhibition by which the nervous system sharpens sensory transitions. PMID:14584991

  5. Concentration-Response and Residual Activity of Insecticides to Control Herpetogramma phaeopteralis (Lepidoptera: Crambidae) in St. Augustinegrass.

    PubMed

    Tofangsazi, Nastaran; Cherry, Ron H; Beeson, Richard C; Arthurs, Steven P

    2015-04-01

    Tropical sod webworm, Herpetogramma phaeopteralis Guenée, is an important pest of warm-season turfgrass in the Gulf Coast states of the United States, the Caribbean Islands, and Central America. Current control recommendations rely on topical application of insecticides against caterpillars. The objective of this study was to generate resistance baseline data of H. phaeopteralis to six insecticide classes. Residual activity of clothianidin, chlorantraniliprole, and bifenthrin was also compared under field conditions in Central Florida. Chlorantraniliprole was the most toxic compound tested (LC50 value of 4.5 ppm), followed by acephate (8.6 ppm), spinosad (31.1 ppm), clothianidin (46.6 ppm), bifenthrin (283 ppm) and Bacillus thuringiensis kurstaki, (342 ppm). In field tests, all compounds at label rates were effective (≥94% mortality of larvae exposed to fresh residues). However, a more rapid decline in activity of clothianidin and bifenthrin was observed compared with chlorantraniliprole. Clothianidin had no statistically detectable activity after 4 wk post-application in spring and the fall, and bifenthrin had no detectable activity after 3 wk in the spring and the fall. However, chlorantraniliprole maintained significant activity (≥84% mortality) compared with other treatments throughout the 5-wk study period. This study provides new information regarding the relative toxicities and persistence of current insecticides used for H. phaeopteralis and other turfgrass caterpillars. PMID:26470184

  6. Mathemagenic Activities Program: [Reports from a Conference on New Perspectives in Developmental Assessment (1st, Athens, Georgia, November 15, 1972)].

    ERIC Educational Resources Information Center

    Smock, Charles D., Ed.; And Others

    This set of four research reports is a product of the Mathemagenic Activities Program (MAP) for early childhood education of the University of Georgia Follow Through Program. Based on Piagetian theory, the MAP provides sequentially structured sets of curriculum materials and processes that are designed to continually challenge children in…

  7. Safeguarding Collections at the Dawn of the 21st Century: Describing Roles & Measuring Contemporary Preservation Activities in ARL Libraries

    ERIC Educational Resources Information Center

    Meyer, Lars

    2009-01-01

    Preservation has long been considered a fundamental responsibility of research libraries. Data on preservation activities by its members has been collected by the Association of Research Libraries (ARL) since 1987, but changing digital technologies and the research, teaching, and learning environments in which research libraries are engaged…

  8. Behavior Change and the Freshman 15: Tracking Physical Activity and Dietary Patterns in 1st-Year University Women

    ERIC Educational Resources Information Center

    Jung, Mary Elizabeth; Bray, Steven Russell; Ginis, Kathleen Anne Martin

    2008-01-01

    Objective and Participants: The authors assessed the stability of diet and physical activity and their relationship to weight changes in first-year university women. Methods: They collected anthropometric and body composition data from 101 resident women at the beginning of their first year of college and again at 12 months. The authors obtained…

  9. Volume 1, 1st Edition, Multiscale Tailoring of Highly Active and Stable Nanocomposite Catalysts, Final Technical Report

    SciTech Connect

    Veser, Goetz

    2009-08-31

    Nanomaterials have gained much attention as catalysts since the discovery of exceptional CO oxidation activity of nanoscale gold by Haruta. However, many studies avoid testing nanomaterials at the high-temperatures relevant to reactions of interest for the production of clean energy (T > 700°C). The generally poor thermal stability of catalytically active noble metals has thus far prevented significant progress in this area. We have recently overcome the poor thermal stability of nanoparticles by synthesizing a platinum barium-hexaaluminate (Pt-BHA) nanocomposite which combines the high activity of noble metal nanoparticles with the thermal stability of hexaaluminates. This Pt-BHA nanocomposite demonstrates excellent activity, selectivity, and long-term stability in CPOM. Pt-BHA is anchored onto a variety of support structures in order to improve the accessibility, safety, and reactivity of the nanocatalyst. Silica felts prove to be particularly amenable to this supporting procedure, with the resulting supported nanocatalyst proving to be as active and stable for CPOM as its unsupported counterpart. Various pre-treatment conditions are evaluated to determine their effectiveness in removing residual surfactant from the active nanoscale platinum particles. The size of these particles is measured across a wide temperature range, and the resulting “plateau” of stability from 600-900°C can be linked to a particle caging effect due to the structure of the supporting ceramic framework. The nanocomposites are used to catalyze the combustion of a dilute methane stream, and the results indicate enhanced activity for both Pt-BHA as well as ceria-doped BHA, as well as an absence of internal mass transfer limitations at the conditions tested. In water-gas shift reaction, nanocomposite Pt-BHA shows stability during prolonged WGS reaction and no signs of deactivation during start-up/shut-down of the reactor. The chemical and thermal stability, low molecular weight, and

  10. ST-segment elevation: Distinguishing ST elevation myocardial infarction from ST elevation secondary to nonischemic etiologies

    PubMed Central

    Deshpande, Alok; Birnbaum, Yochai

    2014-01-01

    The benefits of early perfusion in ST elevation myocardial infarctions (STEMI) are established; however, early perfusion of non-ST elevation myocardial infarctions has not been shown to be beneficial. In addition, ST elevation (STE) caused by conditions other than acute ischemia is common. Non-ischemic STE may be confused as STEMI, but can also mask STEMI on electrocardiogram (ECG). As a result, activating the primary percutaneous coronary intervention (pPCI) protocol often depends on determining which ST elevation patterns reflect transmural infarction due to acute coronary artery thrombosis. Coordination of interpreting the ECG in its clinical context and appropriately activating the pPCI protocol has proved a difficult task in borderline cases. But its importance cannot be ignored, as reflected in the 2013 American College of Cardiology Foundation/American Heart Association guidelines concerning the treatment of ST elevation myocardial infarction. Multiples strategies have been tested and studied, and are currently being further perfected. No matter the strategy, at the heart of delivering the best care lies rapid and accurate interpretation of the ECG. Here, we present the different patterns of non-ischemic STE and methods of distinguishing between them. In writing this paper, we hope for quicker and better stratification of patients with STE on ECG, which will lead to be better outcomes. PMID:25349651

  11. St. John's Wort (image)

    MedlinePlus

    The herb St. John's Wort is believed to be helpful in relieving mild to moderate depression, but should only be taken under a physician's supervision. St. John's Wort may clash with other medications or foods ...

  12. St. John's Wort

    MedlinePlus

    ... 359–366. St. John's wort. Natural Medicines Comprehensive Database Web site. Accessed at www.naturaldatabase.com on February ... St. John's wort ( Hypericum perforatum L.). Natural Standard Database Web site. Accessed at www.naturalstandard.com on February ...

  13. The Greening of St Patrick's.

    ERIC Educational Resources Information Center

    Barron, Jennie

    1993-01-01

    The grade 6-7 class at St. Patrick's School in Hamilton (Ontario) engages in outdoor environmental projects to enhance classroom learning. Some student activities have been (1) worm composting; (2) tree planting; (3) restoring tern nesting areas; and (4) planning and cultivating a sophisticated garden on school grounds. (KS)

  14. The fishes of George Washington Carver National Monument, Missouri, 2003

    USGS Publications Warehouse

    Justus, B.G.; Petersen, James C.

    2005-01-01

    Fish were collected at six sites at George Washington Carver National Monument by seining and electrofishing during a base-flow period on July 17-18, 2003. Approximately 700 fish were collected and identified at the six sampling sites. Those individuals represented 17 species (and 1 hybrid) and 13 genera. The number of species collected at the five stream sites ranged from 9 to 12; a hybrid sunfish and 4 species were collected from a pond. Fish collected at stream sites were typical of small headwater streams and no species collected in this study are federally-listed threatened or endangered species. The three most common species were the southern redbelly dace, central stoneroller, and green sunfish. Some differences existed between the assemblages (groups of species) collected in 2003 and in the previous inventories. Four of the 17 fish species collected in this inventory previously had not been collected at the monument. However, 11 species collected in one or more of the previous inventories were not collected in this effort. There is no indication that a change in environmental conditions is responsible for the absence of these species; more likely reasons are seasonal variability, extirpation, low population density, and misidentification. Four species collected at George Washington Carver National Monument may be of special interest to National Park Service managers and others. The cardinal shiner and stippled darter are endemic to the Ozark Plateaus. The Arkansas darter is considered a species of conservation concern by the State of Missouri. The grass carp is an introduced species.

  15. Invertebrate predators of zooplankton on Georges Bank, 1977 1987

    NASA Astrophysics Data System (ADS)

    Sullivan, Barbara K.; Meise, Carol J.

    Chaetognaths, primarily Sagitta elegans, were the most abundant and widespread invertebrate predator on Georges Bank during 1977-1987 MARMAP surveys. They were present in 79% of samples collected, and their average abundance was nearly an order of magnitude greater than that of any other predator taxon. hydrozoan and scyphozoan medusae, euphausiid shrimp, and gammarid and hyperiid amphipods were also abundant. Diversity and abundance of predators was highest in the central, well-mixed region of the bank. In this region numbers of chaetognaths and cnidaria increased following increased abundances of Calanus finmarchicus. However, on a larger scale the density of C. finmarchicus populations was inversely correlated with number of predators because this herbivore was most abundant in deeper waters surrounding Georges Bank where predators were least numerous. Chaetognaths and cnidaria were more abundant in 1978-1979 than in other years, and there was a statistically significant decline in the abundance of chaetognaths over the 10 year period. Abundance of both these groups was inversely correlated with temperature. Average numbers of chaetognaths in summer were low following a warm winter. Abundance of cnidaria in summer decreased with increasing summer temperatures.

  16. Resuscitation great. George W. Crile: a visionary mind in resuscitation.

    PubMed

    Soto-Ruiz, Karina M; Varon, Joseph

    2009-01-01

    George Washington Crile was a successful surgeon who lived at the end of the 19th century. He was born on 11 November 1864 on a farm near Chili, Ohio. He became interested in the study of shock after a close friend died from hemorrhage. Crile dedicated his research years to the study of shock, cardiac arrest, and the use of adrenaline. His research on shock and cardiac arrest led to treatment guidelines that are still used today. He also participated in the Spanish-American War and in World War I as a Navy Surgeon and saved the lives of many soldiers with his principles of blood transfusion and sanitation. He is also known in the surgical world as the grandfather of radical neck dissection and received the Gold Lannelongue Medal and prize. Having written over 400 papers and 24 books, George W. Crile died from complications of bacterial endocarditis on 7th January 1943. Although they were published a long time ago, his contributions to medicine remain fundamental to clinical practice in today's operating rooms and critical care units. PMID:18951679

  17. Impacts of exploratory drilling for oil and gas on the benthic environment of Georges Bank

    USGS Publications Warehouse

    Neff, J. M.; Bothner, Michael H.; Maciolek, N. J.; Grassle, J. F.

    1989-01-01

    Cluster analysis revealed a strong relationship between community structure and both sediment type and water depth. Little seasonal variation was detected, but some interannual differences were revealed by cluster analysis and correspondence analysis. The replicates from a station always resembled each other more than they resembled any replicates from other stations. In addition, the combined replicates from a station always clustered with samples from that station taken on other cruises. This excellent replication and uniformity of the benthic infaunal community at a station over time made it possible to detect very subtle changes in community parameters that might be related to discharges of drilling fluid and drill cuttings. Nevertheless, no changes were detected in benthic communities of Georges Bank that could be attributed to drilling activities.

  18. The new Computational and Data Sciences Undergraduate Program at George Mason University

    NASA Astrophysics Data System (ADS)

    Borne, K. D.; Wallin, J. F.

    2008-12-01

    We present the new undergraduate program in Computational and Data Sciences at George Mason University. The goals of the program are to train the next-generation scientists in the tools and techniques of cyber-enabled science. New courses include Introduction to Computational and Data Sciences, Scientific Data and Databases, Scientific Data and Information Visualization, Scientific Data Mining, and Scientific Modeling and Simulation. This is an interdisciplinary program, drawing examples, classroom materials, and student activities from a broad range of physical and biological sciences, including Space Physics (and Space Weather), Solar Physics, Astronomy, Geosciences, Geoinformatics, Materials Science, Bioinformatics, Chemistry, and Physics. We will describe some of the motivations and early results from the program.

  19. Potential utilization of the NASA/George C. Marshall Space Flight Center in earthquake engineering research

    NASA Technical Reports Server (NTRS)

    Scholl, R. E. (Editor)

    1979-01-01

    Earthquake engineering research capabilities of the National Aeronautics and Space Administration (NASA) facilities at George C. Marshall Space Flight Center (MSFC), Alabama, were evaluated. The results indicate that the NASA/MSFC facilities and supporting capabilities offer unique opportunities for conducting earthquake engineering research. Specific features that are particularly attractive for large scale static and dynamic testing of natural and man-made structures include the following: large physical dimensions of buildings and test bays; high loading capacity; wide range and large number of test equipment and instrumentation devices; multichannel data acquisition and processing systems; technical expertise for conducting large-scale static and dynamic testing; sophisticated techniques for systems dynamics analysis, simulation, and control; and capability for managing large-size and technologically complex programs. Potential uses of the facilities for near and long term test programs to supplement current earthquake research activities are suggested.

  20. George Herbert Mead and the Allen controversy at the University of Wisconsin.

    PubMed

    Cook, Gary A

    2007-01-01

    This essay uses previously unpublished correspondence of George Herbert Mead to tell the story of his involvement in the aftermath of a political dispute that took place at the University of Wisconsin during the years 1914-1915. It seeks thereby to clarify the historical significance of an article he published on this controversy in late 1915. Taken together with relevant information about the educational activities of William H. Allen of the New York Bureau of Municipal Research, Mead's correspondence and article throw helpful light upon his understanding of how an educational survey of a university should proceed; they also show how he went about the task of evaluating a failed attempt at such a survey. PMID:17205543

  1. Bioaccumulation of heavy metals in marine organisms and sediments from Admiralty Bay, King George Island, Antarctica.

    PubMed

    Trevizani, Tailisi Hoppe; Figueira, Rubens Cesar Lopes; Ribeiro, Andreza Portella; Theophilo, Carolina Yume Sawamura; Majer, Alessandra Pereira; Petti, Monica Angélica Varella; Corbisier, Thais Navajas; Montone, Rosalinda Carmela

    2016-05-15

    The Antarctic continent is considered a low-impact environment; however, there is a tendency to increase the contaminants' levels due to human activities in the research stations. In this study, As, Cd, Cr, Cu, Hg, Ni, Pb and Zn levels in sediment and biota were determined in the environmental samples from Admiralty Bay (King George Island, Antarctica) collected in 2003. The results demonstrated high concentrations of Cu and Zn in the sediments. There was bioaccumulation of As in the biota from Admiralty Bay and bioaccumulation of Zn specifically in the biota from Martel Inlet. In addition, the results were useful in order to understand the heavy metal levels for the pre-accident condition of Comandante Ferraz Antarctic Station, where an accident occurred in 2012, and also for the comparison with current conditions within the monitoring work developed by INCT-APA (National Institute of Science and Technology for Environmental Research Antarctic). PMID:26936119

  2. St. Louis FUSRAP Lessons Learned

    SciTech Connect

    Eberlin, J.; Williams, D.; Mueller, D.

    2003-02-26

    The purpose of this paper is to present lessons learned from fours years' experience conducting Remedial Investigation and Remedial Action activities at the St. Louis Downtown Site (SLDS) under the Formerly Utilized Sites Remedial Action Program (FUSRAP). Many FUSRAP sites are experiencing challenges conducting Remedial Actions within forecasted volume and budget estimates. The St. Louis FUSRAP lessons learned provide insight to options for cost effective remediation at FUSRAP sites. The lessons learned are focused on project planning (budget and schedule), investigation, design, and construction.

  3. Space Educational Opportunities and Outreach Activities at the Dawn of the 21st Century. A European Students Perspective

    NASA Astrophysics Data System (ADS)

    Ferretti, S.; Robinson, D.; Manfletti, C.; Amadori, K.; Boccalatte, A.; Alessandrini, M.; Bedogna, P.; Corradi, P.; Marcuccio, M.

    2002-01-01

    Taking part in space activities and participating in the development and growth of space project has now become an undeniable reality. Thanks to academic institutions and outreach activities space enthusiasts can engage in numerous and diverse yet unique opportunities. The ESA Outreach Office sees students of every background taking part in its activities. This unique mixture of students of diverse nationalities enthusiastically co-operating ensures the program's interdisciplinarity. The added value of such an environment to the programs is significant and must not be forgotten. The friendship that blossom, and lose with which cultural and language barriers are overcome during the time spent working on the projects offered to university student and young professionals are invaluable. The purpose of this abstract is to give our perspective to the space community and to the general public on the importance of developing a space culture. The academic value of the space research projects mainly in which the authors have participated, the importance of such projects for the future of European relations and personal and social development through experience of international teams are topics that will be addressed. The activities discussed are : Attending sessions of congresses around the world, making contacts of major companies and players in the space sector, dealing of topics such as space engineering, policy and law, life sciences, business and finance, satellite applications, the exhilaration of floating in zero-g, the interdisciplinary, international and intercultural approach, the chance of quickly learning about many new concepts are just some of the marvellous experiences and opportunities that these programs offer. Reaching out to the general public is the second purpose of these unique activities.Images, photos and reports can seep into every house thanks to the great instrument that is the media, thus informing almost everyone about the activities and

  4. Have We Entered a 21st Century Prolonged Minimum of Solar Activity? Updated Implications of a 1987 Prediction

    NASA Astrophysics Data System (ADS)

    Shirley, James H.

    2009-05-01

    Fairbridge and Shirley (1987) predicted that a new prolonged minimum of solar activity would be underway by the year 2013 (Solar Physics 110, 191). While it is much too early to tell if this prediction will be fully realized, recent observations document a striking reduction in the Sun's general level of activity. While other forecasts of reduced future activity levels on decadal time scales have appeared, the Fairbridge-Shirley (FS) prediction is unique in pinpointing the current epoch. We are unaware of any forecast method that shows a better correspondence with the actual behavior of the Sun to this point. The FS prediction was based on the present-day recurrence of two physical indicators that were correlated in time with the occurrence of the Wolf, Sporer, and Maunder Minima. The amplitude of the inertial revolution of the axis of symmetry of the Sun's orbital motion about the solar system barycenter, and the direction in space of that axis, each bear a relationship to the occurrence of the prolonged minima of the historic record. The FS prediction appeared before the importance of solar meridional flows was generally appreciated, and before the existence and role of the tachocline was suspected. We will update and restate some of the physical implications of the FS results, along with those of some more recent investigations, particularly with reference to orbit-spin coupling hypotheses (Shirley, 2006: M.N.R.A.S. 368, 280). New investigations combining and integrating modern dynamo models with physical solutions describing key aspects of the variability of the solar motion may lead to significant advances in our ability to forecast future changes in the Sun. Acknowledgement: This work was supported by the resources of the author. No part of this work was performed at the Jet Propulsion Laboratory under a contract from NASA.

  5. Social Justice, Competition and Quality: 21st Century Leadership Challenges. The 2012 Yearbook of the National Council of Professors of Educational Administration

    ERIC Educational Resources Information Center

    Perreault, George, Ed.; Zellner, Luana, Ed.

    2012-01-01

    This is the 2012 Yearbook of the National Council of Professors of Educational Administration (NCPEA). This Yearbook contains the following papers: (1) Editors' Sidebar (George Perreault and Luana Zellner); (2) The Hour Glass Economy: The Social Justice Challenge for the 21st Century (Fenwick W. English); (3) Maintaining the Human Touch in…

  6. George Washington and the Temple of Democracy. Teaching with Historic Places.

    ERIC Educational Resources Information Center

    Hunter, Kathleen A.

    This document, from the lesson plan series, "Teaching with Historic Places," provides a description of George Washington's life and the building of the U.S. Capitol. George Washington became the first U.S. President after leading the colonies through the revolutionary war. The U.S. Congress and the President decided to create a federal city on the…

  7. 75 FR 12563 - Patuxent Research Refuge, Anne Arundel and Prince George's Counties, MD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-16

    ... Fish and Wildlife Service Patuxent Research Refuge, Anne Arundel and Prince George's Counties, MD... process for developing a CCP for Patuxent Research Refuge, in Anne Arundel and Prince George's Counties... the Patuxent and Little Patuxent Rivers between Washington, DC, and Baltimore, Maryland, the...

  8. 77 FR 61624 - Patuxent Research Refuge, Prince George's and Anne Arundel Counties, MD; Draft Comprehensive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ... Federal Register (75 FR 12563; March 16, 2010). Patuxent RR was established in 1936 by Executive Order by... Fish and Wildlife Service Patuxent Research Refuge, Prince George's and Anne Arundel Counties, MD... environmental assessment (CCP/EA) for Patuxent Research Refuge (Patuxent RR), located in Prince George's...

  9. The Oral History of Evaluation: The Professional Development of George Grob

    ERIC Educational Resources Information Center

    Miller, Robin L.; Caracelli, Valerie J.

    2014-01-01

    In this article the authors present the full interview conducted with George Grob in 2011 at the American Evaluation Association (AEA) Conference in Anaheim, CA. George Grob is former Director of the Office of Evaluation and Inspections in the Office of Inspector General. Prior to serving in that Office, he was Director of Planning and Policy…

  10. 75 FR 66138 - George Mathew, M.D.; Denial of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-27

    ... Purchasing Controlled Substances over the Internet, 66 FR 21181. Therein, the Agency explained that ``Federal... Enforcement Administration George Mathew, M.D.; Denial of Application On September 19, 2005, I, the Deputy... Registration to George Mathew, M.D. (Respondent), of Seattle, Washington. The Order proposed the revocation...

  11. Employee Perceptions of the Racial Climate at Prince George's Community College, Spring 1992.

    ERIC Educational Resources Information Center

    Boughan, Karl

    The 1990 U.S. Census's discovery that Prince George's County in Maryland had become the nation's first basically middle-class, majority nonwhite county prompted Prince George's Community College (PGCC) to assess how well it was responding to the challenges of the new multiculturalism. In spring 1992, a racial climate attitude survey was developed…

  12. The Context for Planning: A Report to the Jackson-George Regional Library System.

    ERIC Educational Resources Information Center

    McCook, Kathleen de la Pena; And Others

    This report describes a study of the Jackson-George Regional Library (JGRL) System, which serves a 2-county area in Mississippi with a population of 131,918. The purpose of the study, which built on the planning and administration goals identified in "Planning for Progress: The Long Range Plan of the Jackson George Regional Library," was to…

  13. 21st Century jobs initiative - building the foundations for a 21st Century economy. Executive summary

    SciTech Connect

    1995-11-01

    This document summarizes the principal findings, conclusions, and recommendations of the first year of the 21st Century Jobs Initiative. Launched by leaders of the the 15-county {open_quotes}Resource Valley,{close_quotes} the Jobs Initiative is an action-oriented strategic plan that responds to the region`s most pressing economic challenges. Department of Energy funds have supported the initiative and Tennessee`s Resource Valley, the region`s premier marketing and promotion organization, has spearheaded the project. Consulting assistance has been provided by a team lead by DRI/McGraw-Hill`s Economic Competitiveness Group and IC{sup 2}, Dr. George Kozmetsky`s organization affiliated with the University of Texas at Austin. The consultants have developed several reports and other materials that may be of interest to the reader.

  14. Mount St. Helens Rebirth

    NASA Technical Reports Server (NTRS)

    2002-01-01

    could be seen falling from the sky over the Great Plains, more than 1500 km distant. This image was acquired by Landsat 7 on Aug. 22, 1999. It was produced at 30-m resolution using bands 3, 2, and 1 to display red, green, and blue, respectively ('true color'). Some of the effects of the massive eruption on May 18, 1980, can still be seen clearly, especially on the northern and eastern flanks of Mount St. Helens, which are still mostly barren (shades of white and gray). The crater is in the center of the image. Note the streaking from the crater (gray on the image). These are the remnants of pyroclastic flows (superheated avalanches of gas, ash and pieces of rock) that carved deep channels down the slopes and onto the relatively flat areas near the base of the mountain. The partially-filled Spirit Lake can be seen just to the northeast of the crater (blue-black on the image), and the where most of the energy was directed during the blast is the gray area immediately to the northwest of the crater. However, on other parts of the mountain, the rejuvenation process is obvious. Ash deposits have supplied minerals which have accelerated vegetation growth (various shades of green). Though far from what it looked like 20 years ago, Mount St Helens is actively recovering. Data courtesy Landsat 7 project and EROS Data Center. Caption by James Foster, NASA Goddard Space Flight Center.

  15. Mount St. Helens Flyover

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) image of Mt. St. Helens volcano in Washington State was acquired on August 8, 2000 and covers an area of 37 by 51 km. Mount Saint Helens, a volcano in the Cascade Range of southwestern Washington that had been dormant since 1857, began to show signs of renewed activity in early 1980. On 18 May 1980, it erupted with such violence that the top of the mountain was blown off, spewing a cloud of ash and gases that rose to an altitude of 19 kilometers. The blast killed about 60 people and destroyed all life in an area of some 180 square kilometers (some 70 square miles), while a much larger area was covered with ash and debris. It continues to spit forth ash and steam intermittently. As a result of the eruption, the mountain's elevation decreased from 2,950 meters to 2,549 meters. The simulated fly-over was produced by draping ASTER visible and near infrared image data over a digital topography model, created from ASTER's 3-D stereo bands. The color was computer enhanced to create a 'natural' color image, where the vegetation appears green. The topography has been exaggerated 2 times to enhance the appearance of the relief. Landsat7 aquired an image of Mt. St. Helens on August 22, 1999. Image and animation courtesy NASA/GSFC/MITI/ERSDAC/JAROS, and U.S./Japan ASTER Science Team.

  16. ACL reconstruction in sports active people: transtibial DB technique with ST/G vs. transtibial SB technique with BPTB: preliminary results.

    PubMed

    Volpi, Piero; Cervellin, Matteo; Denti, Matteo; Bait, Corrado; Melegati, Gianluca; Quaglia, Alessandro; de Girolamo, Laura

    2010-11-01

    The single-bundle ACL reconstruction ensures good outcomes and it is a well-established and widespread technique. Nevertheless, some patients still present residual pain and instability. Recent studies have showed that the double-bundle technique restores better natural ACL-fitting kinematics. Long-term clinical studies comparing the two surgical techniques are not frequent and there is no instrument to evaluate function and kinematics during the knee rotation in vivo. In this randomised prospective study performed on sportive people, we compare the BPTB single-bundle ACL reconstruction technique, which is the most common surgical technique performed on these patients' category, with the ACL double-bundle reconstruction technique (DB), in order to evaluate possible differences between the groups. Comparing the two groups, no statistically significant difference regarding the post-operative Lysholm score (p=0.368) the Tegner activity scale (p=0.519) and the arthrometric evaluation with KT-1000 (p=0.74) have been observed. On the contrary, the IKDC evaluation showed a statistically significant difference (p=0.004) better results of the DB group. Moreover, as assessed by the Tegner activity scale, only patients of the DB group were able to return to sports at a pre-injury level. Our data suggest that the double bundle ST/G ACL reconstruction technique results into slightly better outcome than the traditional technique of single-bundle BPTB. The verification and quantification of the advantages of this technique is anticipated with future studies focusing to the accurate measurement of knee rotation during different activities. PMID:20934698

  17. Bering Sea summary report: Outer Continental Shelf oil and gas activities in the Bering Sea and their onshore impacts

    SciTech Connect

    Deis, J.; Pierson, R.; Kurz, F.

    1983-09-01

    Two federal offshore oil-and-gas lease sales have been held in the Bering Sea Subregion. Lease Sale 57, Norton Basin, was held on March 15, 1983. Lease Sale 70, St. George Basin, was held on April 12, 1983. The sale offered 479 tracts, of which 97 received bids. The Department of the Interior has indicated that it will accept 96 of the 97 high bids; however, to date, leases have not been awarded. The Department of the Interior was enjoined from issuing leases by the US District Court of Alaska because of possible impacts from postlease preliminary seismic activities on gray and right whales. In accordance with the Court's ruling, leases cannot be issued until the completion of a supplemental environmental impact statement, which is anticipated to occur in November 1983. Six lease offerings in the Bering Sea Subregion are scheduled through 1987. Six deep stratigraphic test wells are the only wells drilled to date in the Bering Sea Subregion. To date, oil companies have not submitted exploration plans for the Norton Basin Planning Area. Exploration in Norton Basin could begin in the summer of 1984, at the earliest. Exploration plans cannot be submitted for the St. George Basin Planning Area until the leases are awarded. At this time, various onshore areas are being considered as possible support bases for offshore oil-and-gas exploration. At this stage, before exploratory drilling has occurred and in the absence of a commercial discovery, plans for transporting petroleum from the Bering Sea to markets in the United States are unclear. The current estimates of risked resources for lands leased in Lease Sale 57, Norton Basin, are 33 million barrels of oil and 110 billion cubic feet of gas. Lease Sale 70, St. George Basin, estimates of risked resources for leased lands are 27 million barrels of oil and 310 billion cubic feet of gas. 55 references, 10 figures, 3 tables.

  18. Admission Lipoprotein-Associated Phospholipase A2 Activity Is Not Associated with Long-Term Clinical Outcomes after ST-Segment Elevation Myocardial Infarction

    PubMed Central

    Woudstra, Pier; Damman, Peter; Kuijt, Wichert J.; Kikkert, Wouter J.; Grundeken, Maik J.; van Brussel, Peter M.; Stroobants, An K.; van Straalen, Jan P.; Fischer, Johan C.; Koch, Karel T.; Henriques, José P. S.; Piek, Jan J.; Tijssen, Jan G. P.; de Winter, Robbert J.

    2014-01-01

    Background Lipoprotein-associated phospholipase A2 (Lp-PLA2) activity is a biomarker predicting cardiovascular diseases in a real-world. However, the prognostic value in patients undergoing primary percutaneous coronary intervention (pPCI) for ST-segment elevation myocardial infarction (STEMI) on long-term clinical outcomes is unknown. Methods Lp-PLA2 activity was measured in samples obtained prior to pPCI from consecutive STEMI patients in a high-volume intervention center from 2005 until 2007. Five years all-cause mortality was estimated with the Kaplan-Meier method and compared among tertiles of Lp-PLA2 activity during complete follow-up and with a landmark at 30 days. In a subpopulation clinical endpoints were assessed at three years. The prognostic value of Lp-PLA2, in addition to the Thrombolysis In Myocardial Infarction or multimarker risk score, was assessed in multivariable Cox regression. Results The cohort (n = 987) was divided into tertiles (low <144, intermediate 144–179, and high >179 nmol/min/mL). Among the tertiles differences in baseline characteristics associated with long-term mortality were observed. However, no significant differences in five years mortality in association with Lp-PLA2 activity levels were found; intermediate versus low Lp-PLA2 (HR 0.97; CI 95% 0.68–1.40; p = 0.88) or high versus low Lp-PLA2 (HR 0.75; CI 95% 0.51–1.11; p = 0.15). Both in a landmark analysis and after adjustments for the established risk scores and selection of cases with biomarkers obtained, non-significant differences among the tertiles were observed. In the subpopulation no significant differences in clinical endpoints were observed among the tertiles. Conclusion Lp-PLA2 activity levels at admission prior to pPCI in STEMI patients are not associated with the incidence of short and/or long-term clinical endpoints. Lp-PLA2 as an independent and clinically useful biomarker in the risk stratification of STEMI patients still remains to be proven

  19. Map showing landslide susceptibility in Prince Georges County, Maryland

    SciTech Connect

    Pomeroy, J.S.

    1989-01-01

    Prince Georges County was identified during a statewide investigation of landslide susceptibility (MF-2048) as the county with the most serious slope-stability problems. This map uses a ranking system ranging from 1 (nil to very low susceptibility) to 4 (moderate to severe susceptibility). Geologic factors and precipitation are major elements in the initiation of landslides in the county. The Potomac Group and the Marlboro Clay are the most slideprone units. This map should enable users to make a rapid, generalized evaluation of the potential for mass movement. Planners, engineers, soil scientists, geologist, university faculty, and elected officials should find it useful in the assessment of slope hazards for county-wide analyses.

  20. The story of George Huntington and his disease

    PubMed Central

    Bhattacharyya, Kalyan B.

    2016-01-01

    George Huntington described some families with choreiform movements in 1872 in the United States of America and since then many such families have been described in other parts of the world and works on the genetics of the disease have brought new vistas in the understanding of the disease. In 1958, Americo Negrette, a young Venezuelan physician observed similar subjects in the vicinity of Lake Maracaibo which was presented by his co-worker, Ramon Avilla Giron at New York in 1972 when United States of America had been commemorating the centenary year of Huntington's disease. Nancy Wexler, a psychoanalyst, whose mother had been suffering from the disease attended the meeting and organized a research team to Venezuela and they systematically studied more than 18,000 individuals in order to work out a common pedigree. They identified the genetic locus of the disease in the short arm of chromosome 4 and observed that it was a trinucleotide repeat disorder. PMID:27011624

  1. 1. Remnants of the last lock on the George Washington ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Remnants of the last lock on the George Washington 'Potowmack Canal, just before the barge entered the Potomac River. The latter can be seen through the foliage of the tree which has grown up in the old canal bed. On the left hand side of the photograph, not shown here in its entirety, are the old iron studdings which held the gates, to permit the barges to pass easily into the river. On the right hand side of the photograph is shown the crumbling remains of the lock with their receased oval space clearly shown, into which the lock gate retrieved when the barge was lowered to the next level. The depth from the spot where the individual is shown pointing to the top of the lock, is about 24 or 25 ft., and the canal has been filled up with broken ... - Potowmack Company: Great Falls Canal, Locks No. 3, 4, 5, Great Falls, Fairfax County, VA

  2. 3. View of the mouth of George Washington's 'Potowmack' Canal ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. View of the mouth of George Washington's 'Potowmack' Canal at the Great Falls of the Potomac River. The view is taken from a rock in the Potomac River looking up into the Canal. Trees and dense growth now fill the old aperture which once permitted barges to come down the Ohio Valley onto the broad expanse of the Potomac River. This view, taken September 1, 1943, evidences the very low water then existing on the Potomac River, as is clearly shown by the water marks on the rocks on the left hand side of the photograph. That portion where the individual is standing, up to the height of his hat, is normally underwater. Deep in the sand at this spot was found a part of one of the old hand brought lock hinges which formerly swung the first lock gates ... - Potowmack Company: Great Falls Canal, Locks No. 3, 4, 5, Great Falls, Fairfax County, VA

  3. George Washington Community High School: analysis of a partnership network.

    PubMed

    Bringle, Robert G; Officer, Starla D H; Grim, Jim; Hatcher, Julie A

    2009-01-01

    After five years with no public schools in their community, residents and neighborhood organizations of the Near Westside of Indianapolis advocated for the opening of George Washington Community High School (GWCHS). As a neighborhood in close proximity to the campus of Indiana University-Purdue University Indianapolis, the Near Westside and campus worked together to address this issue and improve the educational success of youth. In fall 2000, GWCHS opened as a community school and now thrives as a national model, due in part to its network of community relationships. This account analyzes the development of the school by focusing on the relationships among the university, the high school, community organizations, and the residents of the Near Westside and highlights the unique partnership between the campus and school by defining the relational qualities and describing the network created to make sustainable changes with the high school. PMID:19593812

  4. SUBSIDENCE, CRUSTAL STRUCTURE, AND THERMAL EVOLUTION OF GEORGES BANK BASIN.

    USGS Publications Warehouse

    Swift, B. Ann; Sawyer, D.S.; Grow, J.A.; Klitgord, Kim D.

    1987-01-01

    A geographical study of Georges Bank basin defines a deep crustal structure that is interpreted in terms of the basin's tectonic and thermal history. Gravity models along three basin cross sections delineate two zones of crustal thinning at the basement hinge zone and oceanic crustal margins. These two zones bound rift-stage crust (about 25 km thick) which underlies the central portion of the basin. Subsidence analysis of the basin, using data from multichannel seismic reflection lines and two COST wells, suggests a rifting and (uniform) extensional origin. Two-dimensional finite difference modeling of the basin defines a crustal structure that concurs with the gravity and subsidence studies. The resulting isotherms show no major changes in the thermal structure since the Late Jurassic. In some areas of the basin, temperature sufficient for oil generation are determined from maturation studies of Jurassic sediments. Hydrocarbon generation is questionable, however, because of the probable lack of proper and sufficient kerogen in the Jurassic deposits.

  5. The story of George Huntington and his disease.

    PubMed

    Bhattacharyya, Kalyan B

    2016-01-01

    George Huntington described some families with choreiform movements in 1872 in the United States of America and since then many such families have been described in other parts of the world and works on the genetics of the disease have brought new vistas in the understanding of the disease. In 1958, Americo Negrette, a young Venezuelan physician observed similar subjects in the vicinity of Lake Maracaibo which was presented by his co-worker, Ramon Avilla Giron at New York in 1972 when United States of America had been commemorating the centenary year of Huntington's disease. Nancy Wexler, a psychoanalyst, whose mother had been suffering from the disease attended the meeting and organized a research team to Venezuela and they systematically studied more than 18,000 individuals in order to work out a common pedigree. They identified the genetic locus of the disease in the short arm of chromosome 4 and observed that it was a trinucleotide repeat disorder. PMID:27011624

  6. [George Herbert Mead. Thought as the conversation of interior gestures].

    PubMed

    Quéré, Louis

    2010-01-01

    For George Herbert Mead, thinking amounts to holding an "inner conversation of gestures ". Such a conception does not seem especially original at first glance. What makes it truly original is the "social-behavioral" approach of which it is a part, and, particularly, two ideas. The first is that the conversation in question is a conversation of gestures or attitudes, and the second, that thought and reflexive intelligence arise from the internalization of an external process supported by the social mechanism of communication: that of conduct organization. It imports then to understand what distinguishes such ideas from those of the founder of behavioral psychology, John B. Watson, for whom thinking amounts to nothing other than subvocal speech. PMID:20533805

  7. Georges Lemaître: Science and Religion

    NASA Astrophysics Data System (ADS)

    Coyne, George V.

    In order to appreciate the contribution which Georges Lemaître made to the relationship between religion and science it is necessary to understand how the Catholic Church, of which he was a priest, passed in the course of three centuries, from a position of conflict with the sciences to one of compatible openness and dialogue. In doing this I hope to show that the natural sciences have played a significant role in helping to establish the kind of dialogue that is absolutely necessary for the enrichment of the multifaceted aspects of human culture. I will speak of the following four periods of history: (l) the rise of modern atheism in the seventeenth and eighteenth centuries; (2) anticlericalism in Europe in the nineteenth century; (3) the awakening within the Catholic Church to modern science in the first six decades of the twentieth century; (4) the Church's view today.

  8. George Hartley Bryan, Ludwig Boltzmann, and the Stability of Flight

    NASA Astrophysics Data System (ADS)

    Boyd, T. James M.

    2012-03-01

    A century ago, George Hartley Bryan (1864-1928) published his classic book, Stability in Aviation. I draw together some strands from events that awakened his interest in the nascent science of aviation, in particular the stability of flight. Prominent among those who influenced him was Ludwig Boltzmann (1844-1906), who held Bryan in high esteem for his contributions to thermodynamics and kinetic theory. I argue that the seeds of Bryan's interest in aviation were sown at the British Association meeting at Oxford in the summer of 1894, at which Boltzmann was guest of honor. A joint discussion between Section A (Mathematical and Physical Science) and Section G (Mechanical Science) was devoted to the problems of flight, during the course of which Boltzmann revealed a hitherto unsuspected enthusiasm for flying.

  9. 4. View looking from the north of George Washington's 'Potowmack' ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. View looking from the north of George Washington's 'Potowmack' Canal at Great Falls on the Potomac River, taken September 1, 1943. The low water of the Potomac is definitely shown by the markings on the bank of the river, immediately across stream from where photograph was taken. The usual water mark existing under normal conditions, is shown on the rock in the immediate foreground at a point about even with the spectator's pipe. The spectator is pointing to the evidences of old drillings made in this hard rock by General Washington and his courageous crew, who either blasted or cleaved this opening in the solid wall of rock, to permit boats to pass around the Great Falls and thence into the Potomac River. In the foreground, a slab of stone is ... - Potowmack Company: Great Falls Canal, Locks No. 3, 4, 5, Great Falls, Fairfax County, VA

  10. Human radiation studies: Remembering the early years. Oral history of Dr. George Voelz, M.D., November 29, 1994

    SciTech Connect

    1995-05-01

    Dr. George Voelz was interviewed by representatives of the US DOE Office of Human Radiation Experiments (OHRE). This oral history covers Dr. Voelz`s research on Manhattan Engineering District plutonium workers, the acute and long term effects of radiation, his inhalation studies, and his activities at the 1961 INL reactor accident (SL-1 Reactor). After a brief biographical sketch, Dr. Voelz his remembrances on tissue studies of plutonium workers, the plutonium injection studies of 1945-1946, the controlled environmental radioiodine tests of 1963-1968, and tracer studies with human volunteers at Los Alamos. Dr. Voelz states his opinions concerning misconceptions about the Los Alamos Human Radiation Experiments.

  11. Mobile fishing gear reduces benthic megafaunal production on Georges Bank

    USGS Publications Warehouse

    Hermsen, J.M.; Collie, J.S.; Valentine, P.C.

    2003-01-01

    This study addresses the effect of mobile fishing gear disturbance on benthic megafaunal production on the gravel pavement of northern Georges Bank. From 1994 to 2000, we sampled benthic megafauna with a 1 m Naturalists' dredge at shallow (47 to 62 m) and deep (80 to 90 m) sites. The cessation of fishing in large areas of Georges Bank in January 1995 allowed us to monitor changes in production at a previously disturbed site. Production at a shallow disturbed site varied little over the sampling period (32 to 57 kcal m-2 yr-1) and was markedly lower than production at the nearby recovering site, where production increased from 17 kcal m-2yr -1 in 1994 before the closure to 215 kcal m-2 yr -1 in 2000. Atlantic sea scallops Placopecten magellanicus and green sea urchins Strongylocentrotus droebachiensis dominated production at the recovering site. The community production:biomass ratio decreased over time at the recovering site as the sea scallop population matured. At the deep sites, production remained significantly higher at undisturbed sites (174 to 256 kcal m-2 yr-1) than at disturbed sites (30 to 52 kcal m -2 yr-1). The soft-bodied tube-building polychaete Thelepus cincinnatus dominated production at the undisturbed site, while hard-shelled bivalve molluscs Astarte spp. and P. magellanicus were prevalent at the disturbed site. Mobile fishing gear disturbance has a conspicuous effect on benthic megafaunal production in this hard-bottom habitat. Cessation of mobile fishing has resulted in a marked increase in benthic megafaunal production. These findings should help fishery managers to gauge the costs and benefits of management tools such as area closures and low-impact fishing gears.

  12. Polyphenolic substrates and dyes degradation by yeasts from 25 de Mayo/King George Island (Antarctica).

    PubMed

    Rovati, José I; Pajot, Hipólito F; Ruberto, Lucas; Mac Cormack, Walter; Figueroa, Lucía I C

    2013-11-01

    Antarctica offers a range of extreme climatic conditions, such as low temperatures, high solar radiation and low nutrient availability, and constitutes one of the harshest environments on Earth. Despite that, it has been successfully colonized by ’cold-loving’ fungi, which play a key role in decomposition cycles in cold ecosystems. However, knowledge about the ecological role of yeasts in nutrient or organic matter recycling/mineralization remains highly fragmentary. The aim of this work was to study the yeast microbiota in samples collected on 25 de Mayo/King George Island regarding the scope of their ability to degrade polyphenolic substrates such as lignin and azo dyes. Sixty-one yeast isolates were obtained from 37 samples, including soil, rocks, wood and bones. Molecular analyses based on rDNA sequences revealed that 35 yeasts could be identified at the species level and could be classified in the genera Leucosporidiella, Rhodotorula, Cryptococcus, Bullera and Candida. Cryptococcus victoriae was by far the most ubiquitous species. In total, 33% of the yeast isolates examined showed significant activity for dye decolorization, 25% for laccase activity and 38% for ligninolytic activity. Eleven yeasts did not show positive activity in any of the assays performed and no isolates showed positive activity across all tested substrates. A high diversity of yeasts were isolated in this work, possibly including undescribed species and conspicuous Antarctic yeasts, most of them belonging to oligotrophic, slow-growing and metabolically diverse basidiomycetous genera. PMID:24298603

  13. Mt. St. Helens

    NASA Technical Reports Server (NTRS)

    2001-01-01

    [figure removed for brevity, see original site] [figure removed for brevity, see original site] Figure 1 Movie

    This 3-D anaglyph image of Mt. St. Helens volcano combines the nadir-looking and back-looking band 3 images of ASTER. To view the image in stereo, you will need blue-red glasses. Make sure to look through the red lens with your left eye. Figure 1: This ASTER image of Mt. St. Helens volcano in Washington was acquired on August 8, 2000 and covers an area of 37 by 51 km. Mount Saint Helens, a volcano in the Cascade Range of southwestern Washington that had been dormant since 1857, began to show signs of renewed activity in early 1980. On 18 May 1980, it erupted with such violence that the top of the mountain was blown off, spewing a cloud of ash and gases that rose to an altitude of 19 kilometers. The blast killed about 60 people and destroyed all life in an area of some 180 square kilometers (some 70 square miles), while a much larger area was covered with ash and debris. It continues to spit forth ash and steam intermittently. As a result of the eruption, the mountain's elevation decreased from 2,950 meters to 2,549 meters. The image is centered at 46.2 degrees north latitude, 122.2 degrees west longitude.

    Movie: The simulated fly-over was produced by draping ASTER visible and near infrared image data over a digital topography model, created from ASTER's 3-D stereo bands. The color was computer enhanced to create a natural color image, where the vegetation appears green. The topography has been exaggerated 2 times to enhance the appearance of the relief.

    The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

  14. George Gaylord Simpson as mentor and apologist for paleoanthropology.

    PubMed

    Laporte, L F

    1991-01-01

    The influence of George Gaylord Simpson (1902-1984) on paleoanthropology provides a well-documented, historical example of how one scientific discipline can impact upon another, bringing the latter quickly "up to speed" without having to retrace ground covered by the former. Paleoanthropologists were bystanders during the formulation of the evolutionary synthesis (1936-1947). After World War II, the younger paleoanthropologists looked to George Gaylord Simpson as one of several mentors regarding the implications of the synthesis for their own discipline. But why Simpson? Having earlier defined the superfamily Hominoidea (1931) as holding the Pongidae and Hominidae and monographed lower primate fossils (e.g., "Studies on the earliest primates," 1940), Simpson's "Principles of classification and a classification of mammals" (1945) further solidified his reputation as a mammalian systematist. Simpson's Meaning of Evolution (1949) was widely read as an introduction to the synthesis, and his Tempo an Mode in Evolution (1944) made accessible the more complex aspects. Consequently, in the 1950s and 1960s paleoanthropologists invited Simpson to participate in their symposia (e.g., "Some principles of historical biology bearing on human origins," 1951; "The meaning of taxonomic statements," 1964), used his books as classroom texts, and cited his publications to support claims for their own work. Later in the 1960s, Simpson moved from mentor to apologist, as the paleoanthropologists were by then familiar with the synthesis and incorporated its theoretical concepts in their interpretations of the many newly discovered hominoid fossils. Simpson now took special care to celebrate these results in his more general, less technical writings, acting as a forceful apologist for the materialistic view of human origins (e.g., "The biological nature of man," 1966; "The evolutionary concept of man," 1972). During the 1970s, Simpson's influence waned, and he became just another

  15. Role of submarine canyons in shaping the rise between Lydonia and Oceanographer canyons, Georges Bank

    USGS Publications Warehouse

    McGregor, B.A.

    1985-01-01

    Three large submarine canyons, Oceanographer, Gilbert, and Lydonia, indent the U.S. Atlantic continental shelf and, with four additional canyons, dissect the continental slope in the vicinity of Georges Bank. On the upper rise, these canyons merge at a water depth of approximately 3100 m to form only two valleys. Differences in channel morphology of the canyons on the upper rise imply differences in relative activity, which is inconsistent with observations in the canyon heads. At present, Lydonia Canyon incises the upper rise more deeply than do the other canyons: however, seismic-reflection profiles show buried channels beneath the rise, which suggests that these other six canyons were periodically active during the Neogene. The rise morphology and the thickness of inferred Neogene- and Quaternary-age sediments on the rise are attributed to the presence and activity of the canyons. The erosional and depositional processes and the morphology of these canyons are remarkably similar to those of fluvial systems. Bear Seamount, which has approximately 2000 m of relief on the rise, has acted as a barrier to downslope sediment transport since the Late Cretaceous. Sediment has piled up on the upslope side, whereas much less sediment has accumulated in the "lee shadow" on the downslope side. Seismic-reflection profile data show that Lydonia Canyon has not eroded down to the volcanic rock of Bear Seamount. ?? 1985.

  16. Managing public and media response to a reawakening volcano: lessons from the 2004 eruptive activity of Mount St. Helens: Chapter 23 in A volcano rekindled: the renewed eruption of Mount St. Helens, 2004-2006

    USGS Publications Warehouse

    Frenzen, Peter M.; Matarrese, Michael T.

    2008-01-01

    Volcanic eruptions and other infrequent, large-scale natural disturbances pose challenges and opportunities for public-land managers. In the days and weeks preceding an eruption, there can be considerable uncertainty surrounding the magnitude and areal extent of eruptive effects. At the same time, public and media interest in viewing developing events is high and concern for public safety on the part of local land managers and public safety officials is elevated. Land managers and collaborating Federal, State, and local officials must decide whether evacuations or restrictions to public access are necessary, the appropriate level of advance preparation, and how best to coordinate between overlapping jurisdictions. In the absence of a formal Federal or State emergency declaration, there is generally no identified source of supplemental funding for emergency-response preparation or managing extraordinary public and media response to developing events. In this chapter, we examine responses to escalating events that preceded the 2004 Mount St. Helens eruption and changes in public perception during the extended period of the largely nonexplosive, dome-building eruption that followed. Lessons learned include the importance of maintaining up-to-date emergency-response plans, cultivating close working relationships with collaborating agencies, and utilizing an organized response framework that incorporates clearly defined roles and responsibilities and effective communication strategies.

  17. Ryan ST Sportplane

    NASA Technical Reports Server (NTRS)

    1938-01-01

    Ryan ST (STA Special): The sporty Ryan ST was flown at Langley Memorial Aeronautical Laboratory in research conducted concerning flaps, slats, and internally-balanced ailerons. 'NACA 96' ended its flying career as a familiarization aircraft for new pilots on the NACA staff. In December 1944, it became NACA 125 and was transferred to the Loads Lab located in the West Area.

  18. George Orwell and Modern Science Fiction: The Legacy of Big Brother.

    ERIC Educational Resources Information Center

    Lerner, Fred

    1984-01-01

    Discusses George Orwell's lack of influence on modern science fiction and presents a selected annotated bibliography of modern science fiction materials depicting a wide variety of totalitarian societies. (MBR)

  19. 3. Historic American Buildings Survey, George F.A. Palmer, Photographer, June ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey, George F.A. Palmer, Photographer, June 16, 1936 DETAIL OF HOPPER AND HOISTING MECHANISM (FOR REMOVAL OF MILL STONES. 1757, CUT IN STONE). - Benjamin Hammond Grist Mill, Hammond Hill Road, Kingston, Washington County, RI

  20. 4. Historic American Buildings Survey, George F.A. Palmer, Photographer, June ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey, George F.A. Palmer, Photographer, June 16, 1936 DETAIL OF RECEIVING TROUGH (BASEMENT). - Benjamin Hammond Grist Mill, Hammond Hill Road, Kingston, Washington County, RI

  1. George M. Low Trophy NASA's Quality and Excellence Award, 1992. Application guidelines: Small business

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Guidelines are given for the selection of small business candidates for the George M. Low Trophy, NASA's Quality and Excellence Award, 1992. Topics covered include candidate eligibility, the selection process milestone schedule, the nomination letter, and the application report.

  2. Booker T. Washington and George Washington Carver: A Tandem of Adult Educators at Tuskegee.

    ERIC Educational Resources Information Center

    McGee, Leo

    1984-01-01

    Shows how Booker T. Washington and George Washington Carver espoused adult education principles through their efforts to eradicate illiteracy, teach practical knowledge to Black farmers and poor Blacks, and instill the value of education in Black adults. (SK)

  3. Contributors to Adult Education: Booker T. Washington, George Washington Carver, Alain L. Locke, and Ambrose Caliver.

    ERIC Educational Resources Information Center

    Gyant, LaVerne

    1988-01-01

    Outlines the lives and the contributions to adult education made by the following African American educators: (1) Booker T. Washington; (2) George Washington Carver; (3) Alain L. Locke; and (4) Ambrose Caliver. (BJV)

  4. Filbert Street elevation of James H. Windrim and George Summers’s ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Filbert Street elevation of James H. Windrim and George Summers’s neoclassical competition design for the New Masonic Temple, Philadelphia, 1867 - Masonic Temple, 1 North Broad Street, Philadelphia, Philadelphia County, PA

  5. Broad Street elevation of James H. Windrim and George Summers’s ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Broad Street elevation of James H. Windrim and George Summers’s neoclassical competition design for the New Masonic Temple, Philadelphia, 1867 - Masonic Temple, 1 North Broad Street, Philadelphia, Philadelphia County, PA

  6. George E. KidderSmith, April 1945, Photograph #1338. VIEW OF BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    George E. Kidder-Smith, April 1945, Photograph #133-8. VIEW OF BUILDING 23, FRONT SIDE FROM ACROSS COURTYARD, FACING WEST - Roosevelt Base, Auditorium-Gymnasium, West Virginia Street between Richardson & Reeves Avenues, Long Beach, Los Angeles County, CA

  7. George E. KidderSmith, photographer, April 1945, Photograph #1101. VIEW OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    George E. Kidder-Smith, photographer, April 1945, Photograph #110-1. VIEW OF BUILDING 23, SOUTH SIDE WITH ARCADE, FACING NORTHWEST - Roosevelt Base, Auditorium-Gymnasium, West Virginia Street between Richardson & Reeves Avenues, Long Beach, Los Angeles County, CA

  8. Juniper Street elevation of James H. Windrim and George Summers’s ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Juniper Street elevation of James H. Windrim and George Summers’s neoclassical competition design for the New Masonic Temple, Philadelphia, 1867 - Masonic Temple, 1 North Broad Street, Philadelphia, Philadelphia County, PA

  9. A New Perspective on Mount St. Helens - Dramatic Landform Change and Associated Hazards at the Most Active Volcano in the Cascade Range

    USGS Publications Warehouse

    Ramsey, David W.; Driedger, Carolyn L.; Schilling, Steve P.

    2008-01-01

    Mount St. Helens has erupted more frequently than any other volcano in the Cascade Range during the past 4,000 years. The volcano has exhibited a variety of eruption styles?explosive eruptions of pumice and ash, slow but continuous extrusions of viscous lava, and eruptions of fluid lava. Evidence of the volcano?s older eruptions is recorded in the rocks that build and the deposits that flank the mountain. Eruptions at Mount St. Helens over the past three decades serve as reminders of the powerful geologic forces that are reshaping the landscape of the Pacific Northwest. On May 18, 1980, a massive landslide and catastrophic explosive eruption tore away 2.7 cubic kilometers of the mountain and opened a gaping, north-facing crater. Lahars flowed more than 120 kilometers downstream, destroying bridges, roads, and buildings. Ash from the eruption fell as far away as western South Dakota. Reconstruction of the volcano began almost immediately. Between 1980 and 1986, 80 million cubic meters of viscous lava extruded episodically onto the crater floor, sometimes accompanied by minor explosions and small lahars. A lava dome grew to a height of 267 meters, taller than the highest buildings in the nearby city of Portland, Oregon. Crater Glacier formed in the deeply shaded niche between the 1980-86 lava dome and the south crater wall. Its tongues of ice flowed around the east and west sides of the dome. Between 1989 and 1991, multiple explosions of steam and ash rocked the volcano, possibly a result of infiltrating rainfall being heated in the still-hot interior of the dome and underlying crater floor. In September 2004, rising magma caused earthquake swarms and deformation of the crater floor and glacier, which indicated that Mount St. Helens might erupt again soon. On October 1, 2004, a steam and ash explosion signaled the beginning of a new phase of eruptive activity at the volcano. On October 11, hot rock reached the surface and began building a new lava dome immediately

  10. Transposon Tagging of a Male-Sterility, Female-Sterility Gene, St8, Revealed that the Meiotic MER3 DNA Helicase Activity Is Essential for Fertility in Soybean

    PubMed Central

    Baumbach, Jordan; Pudake, Ramesh N.; Johnson, Callie; Kleinhans, Kaylin; Ollhoff, Alexandrea; Palmer, Reid G.; Bhattacharyya, Madan K.; Sandhu, Devinder

    2016-01-01

    The W4 locus in soybean encodes a dihydroflavonol-4-reductase (DFR2) that regulates pigmentation patterns in flowers and hypocotyl. The mutable w4-m allele that governs variegated flowers has arisen through insertion of a CACTA-type transposable element, Tgm9, in DFR2. In the w4-m line, reversion from variegated to purple flower indicates excision of Tgm9, and its insertion at a new locus. Previously, we have identified a male-sterile, female-sterile mutant among the selfed progenies of a revertant plant carrying only purple flowers. Co-segregation between Tgm9 and the sterility phenotype suggested that the mutant was generated by insertion of Tgm9 at the St8 locus. The transposon was localized to exon 10 of Glyma.16G072300 that shows high identity to the MER3 DNA helicase involved in crossing over. Molecular analysis of fertile branches from two independent revertant plants confirmed precise excision of Tgm9 from the st8 allele, which restored fertility. In soybean, the gene is expressed in flower-buds, trifoliate leaves and stem. Phylogenetic analysis placed St8 in a clade with the Arabidopsis and rice MER3 suggesting that St8 is most likely the orthologous MER3 soybean gene. This study established the utility of Tgm9 in gene identification as well as in forward and reverse genetics studies. PMID:26930200

  11. ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease

    PubMed Central

    Zhang, Jilu; Ramadan, Abdulraouf M.; Griesenauer, Brad; Li, Wei; Turner, Matthew J.; Liu, Chen; Kapur, Reuben; Hanenberg, Helmut; Blazar, Bruce R.; Tawara, Isao; Paczesny, Sophie

    2015-01-01

    Graft-versus-host disease (GVHD) remains a devastating complication after allogeneic hematopoietic cell transplantation (HCT). We previously identified high plasma soluble suppression of tumorigenicity 2 (sST2) as a biomarker of the development of GVHD and death. sST2 sequesters interleukin (IL)-33, limiting its availability to T cells expressing membrane-bound ST2 (mST2) [Th2 cells and ST2+FoxP3+regulatory T cells]. Here, we report that blockade of sST2 in the peri-transplant period with a neutralizing monoclonal antibody (anti-ST2 mAb) reduced GVHD severity and mortality. We identified intestinal stromal cells and T cells as major sources of sST2 during GVHD. ST2 blockade decreased systemic interferon-γ, IL-17, and IL-23 but increased IL-10 and IL-33 plasma levels. ST2 blockade also reduced sST2 production by IL-17–producing T cells while maintaining protective mST2-expressing T cells, increasing the frequency of intestinal myeloid-derived suppressor cells, and decreasing frequency of intestinal CD103 dendritic cells. Finally, ST2 blockade preserved graft-versus-leukemia activity in a model of GFP+MLL-AF9 acute myeloid leukemia. Our findings suggest that ST2 is a therapeutic target for severe GVHD, and that the ST2/IL-33 pathway could be investigated in other T-cell mediated immune disorders with loss of tolerance. PMID:26446957

  12. ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease.

    PubMed

    Zhang, Jilu; Ramadan, Abdulraouf M; Griesenauer, Brad; Li, Wei; Turner, Matthew J; Liu, Chen; Kapur, Reuben; Hanenberg, Helmut; Blazar, Bruce R; Tawara, Isao; Paczesny, Sophie

    2015-10-01

    Graft-versus-host disease (GVHD) remains a devastating complication after allogeneic hematopoietic cell transplantation (HCT). We previously identified high plasma soluble suppression of tumorigenicity 2 (sST2) as a biomarker of the development of GVHD and death. sST2 sequesters interleukin-33 (IL-33), limiting its availability to T cells expressing membrane-bound ST2 (mST2) [T helper 2 (TH2) cells and ST2(+)FoxP3(+) regulatory T cells]. We report that blockade of sST2 in the peritransplant period with a neutralizing monoclonal antibody (anti-ST2 mAb) reduced GVHD severity and mortality. We identified intestinal stromal cells and T cells as major sources of sST2 during GVHD. ST2 blockade decreased systemic interferon-γ, IL-17, and IL-23 but increased IL-10 and IL-33 plasma levels. ST2 blockade also reduced sST2 production by IL-17-producing T cells while maintaining protective mST2-expressing T cells, increasing the frequency of intestinal myeloid-derived suppressor cells, and decreasing the frequency of intestinal CD103 dendritic cells. Finally, ST2 blockade preserved graft-versus-leukemia activity in a model of green fluorescent protein (GFP)-positive MLL-AF9 acute myeloid leukemia. Our findings suggest that ST2 is a therapeutic target for severe GVHD and that the ST2/IL-33 pathway could be investigated in other T cell-mediated immune disorders with loss of tolerance. PMID:26446957

  13. Acoustical Detection of High-Density Krill Demersal Layers in the Submarine Canyons off Georges Bank.

    PubMed

    Greene, C H; Wiebe, P H; Burczynski, J; Youngbluth, M J

    1988-07-15

    High-density demersal layers of krill have been detected in the submarine canyons off Georges Bank by means of a high-frequency, dual-beam bioacoustical technique. Krill densities in these demersal layers were observed to be two to three orders of magnitude greater than the highest densities observed in water-column scattering layers. Such abundances may help explain the unusually high squid and demersal fish production estimates attributed to the Georges Bank ecosystem. PMID:17734865

  14. Establishing the Canon: George Ripley and his alchemical sources.

    PubMed

    Rampling, Jennifer M

    2008-11-01

    George Ripley, Canon of Bridlington (ca. 1415 to ca. 1490) was one of England's most famous alchemists, whose alchemical opera attracted study and commentary throughout the sixteenth and seventeenth centuries, and were printed and translated both in England and abroad. Yet Ripley's frequently baffling texts have proved resistant to scholarly interpretation. This paper attempts to unravel some of Ripley's alchemical theories and practice, firstly by identifying his major sources, and secondly by gauging his response to these texts. For instance, although Ripley's interest in the corpus of alchemical texts pseudonymously attributed to Ramon Lull is well documented, it transpires that his best known work, the Compound of Alchemy, or Twelve Gates, is actually based not on a Lullian work, but on a Latin treatise that Ripley attributed to the little-known alchemist, Guido de Montanor. Further clues to Ripley's alchemical thought can be obtained by considering his handling of a potential conflict between his two authorities, Lull and Guido. The resulting insights into Ripley's alchemy provide an instrument for assessing which of Ripley's pseudoepigraphic works can be truly called "canonical". PMID:19244710

  15. George Feher: a pioneer in reaction center research.

    PubMed

    Okamura, Melvin

    2014-05-01

    Our understanding of photosynthesis has been greatly advanced by the elucidation of the structure and function of the reaction center (RC), the membrane protein responsible for the initial light-induced charge separation in photosynthetic bacteria and green plants. Although today we know a great deal about the details of the primary processes in photosynthesis, little was known in the early days. George Feher made pioneering contributions to photosynthesis research in characterizing RCs from photosynthetic bacteria following the ground-breaking work of Lou Duysens and Rod Clayton (see articles in this issue by van Gorkom and Wraight). The work in his laboratory at the University of California, San Diego, started in the late 1960s and continued for over 30 years. He isolated a pure RC protein and used magnetic resonance spectroscopy to study the primary reactants. Following this pioneering work, Feher studied the detailed structure of the RC and the basic electron and proton transfer functions that it performs using a wide variety of biophysical and biochemical techniques. These studies, together with work from many other researchers, have led to our present detailed understanding of these proteins and their function in photosynthesis. The present article is a brief historical account of his pioneering contributions to photosynthesis research. A more detailed description of his work can be found in an earlier biographical paper (Feher in Photosynth Res 55:1-40, 1998a). PMID:24104959

  16. Digital 3D facial reconstruction of George Washington

    NASA Astrophysics Data System (ADS)

    Razdan, Anshuman; Schwartz, Jeff; Tocheri, Mathew; Hansford, Dianne

    2006-02-01

    PRISM is a focal point of interdisciplinary research in geometric modeling, computer graphics and visualization at Arizona State University. Many projects in the last ten years have involved laser scanning, geometric modeling and feature extraction from such data as archaeological vessels, bones, human faces, etc. This paper gives a brief overview of a recently completed project on the 3D reconstruction of George Washington (GW). The project brought together forensic anthropologists, digital artists and computer scientists in the 3D digital reconstruction of GW at 57, 45 and 19 including detailed heads and bodies. Although many other scanning projects such as the Michelangelo project have successfully captured fine details via laser scanning, our project took it a step further, i.e. to predict what that individual (in the sculpture) might have looked like both in later and earlier years, specifically the process to account for reverse aging. Our base data was GWs face mask at Morgan Library and Hudons bust of GW at Mount Vernon, both done when GW was 53. Additionally, we scanned the statue at the Capitol in Richmond, VA; various dentures, and other items. Other measurements came from clothing and even portraits of GW. The digital GWs were then milled in high density foam for a studio to complete the work. These will be unveiled at the opening of the new education center at Mt Vernon in fall 2006.

  17. Identifying the patient in George W Lambert's Chesham Street

    PubMed Central

    Hammerschlag, Keren Rosa

    2013-01-01

    This paper takes as its focus one of the Edwardian period's most dramatic and little-understood paintings of a medical examination: George Washington Lambert's Chesham Street (1910). The painting shows an upper-class male patient lifting his shirt to reveal a muscular torso for examination by the doctor in the scene and the viewers outside it. The subject of a medical examination, I argue, legitimised the scrutiny of exposed male flesh and offered an opportunity for sensual pleasure between men. By way of a comparison with other portraits of the artist from around the same period, I interpret Chesham Street as a patient self-portrait, which reveals the artist's dual personalities of bohemian artist and Australian boxer: two personae that did not combine seamlessly, as revealed by the composite nature of the patient in Chesham Street. From a discussion of the artist as patient, I move to an analysis of other self-portraits by Lambert in which the artist is shown flexing his muscles, especially in the context of his passion for boxing. I consider how these portraits serve as complex inscriptions of illness and health and how this relates to the experience of living and working as an Australian expatriate artist in London in the early twentieth century. PMID:23349514

  18. GEORG GRODDECK: "THE PINCH OF PEPPER" OF PSYCHOANALYSIS(.).

    PubMed

    Poster, Mark F; Hristeva, Galina; Giefer, Michael

    2016-06-01

    The life and works of Georg Groddeck are reviewed and placed in historical context as a physician and a pioneer of psychoanalysis, psychosomatic medicine, and an epistolary style of writing. His Das Es concept stimulated Freud to construct his tripartite model of the mind. Groddeck, however, used Das Es to facilitate receptivity to unconscious communication with his patients. His "maternal turn" transformed his treatment approach from an authoritarian position to a dialectical process. Groddeck was a generative influence on the development of Frieda Fromm-Reichmann, Erich Fromm, and Karen Horney. He was also the mid-wife of the late-life burst of creativity of his friend and patient Sándor Ferenczi. Together, Groddeck and Ferenczi provided the impetus for a paradigm shift in psychoanalysis that emphasized the maternal transference, child-like creativity, and a dialogue of the unconscious that foreshadowed contemporary interest in intersubjectivity and field theory. They were progenitors of the relational turn and tradition in psychoanalysis. Growing interest in interpsychic communication and field theory is bringing about a convergence of theorizing among pluralistic psychoanalytic schools that date back to 1923 when Freud appropriated Groddeck's Das Es and radically altered its meaning and use. PMID:27194274

  19. Narrative and epistemology: Georges Canguilhem's concept of scientific ideology.

    PubMed

    Chimisso, Cristina

    2015-12-01

    In the late 1960s, Georges Canguilhem introduced the concept of 'scientific ideology'. This concept had not played any role in his previous work, so why introduce it at all? This is the central question of my paper. Although it may seem a rather modest question, its answer in fact uncovers hidden tensions in the tradition of historical epistemology, in particular between its normative and descriptive aspects. The term ideology suggests the influence of Althusser's and Foucault's philosophies. However, I show the differences between Canguilhem's concept of scientific ideology and Althusser's and Foucault's respective concepts of ideology. I argue that Canguilhem was in fact attempting to solve long-standing problems in the tradition of historical epistemology, rather than following the lead of his younger colleagues. I argue that Canguilhem's 'refurbishment without rejection' of Bachelard's epistemology, which the concept of scientific ideology was aimed to implement, was necessary to justify the historical narratives that Canguilhem had constructed in his own work as a historian of concepts. A strict acceptance of Bachelard's epistemology would have made it impossible to justify them. Canguilhem's concept of scientific ideology therefore served as a theoretical justification of his practice as a historian. I maintain that the concept of scientific ideology was needed to reconcile Bachelard's normative epistemology with Canguilhem's view of the history of science and its aims, which differed from Bachelard's more than it is generally acknowledged. PMID:26568088

  20. Phrenology, heredity and progress in George Combe's Constitution of Man.

    PubMed

    Jenkins, Bill

    2015-09-01

    The Constitution of Man by George Combe (1828) was probably the most influential phrenological work of the nineteenth century. It not only offered an exposition of the phrenological theory of the mind, but also presented Combe's vision of universal human progress through the inheritance of acquired mental attributes. In the decades before the publication of Darwin's Origin of Species, the Constitution was probably the single most important vehicle for the dissemination of naturalistic progressivism in the English-speaking world. Although there is a significant literature on the social and cultural context of phrenology, the role of heredity in Combe's thought has been less thoroughly explored, although both John van Wyhe and Victor L. Hilts have linked Combe's views on heredity with the transformist theories of Jean-Baptiste Lamarck. In this paper I examine the origin, nature and significance of his ideas and argue that Combe's hereditarianism was not directly related to Lamarckian transformism but formed part of a wider discourse on heredity in the early nineteenth century. PMID:25998794

  1. Identifying the patient in George W Lambert's Chesham Street.

    PubMed

    Hammerschlag, Keren Rosa

    2013-06-01

    This paper takes as its focus one of the Edwardian period's most dramatic and little-understood paintings of a medical examination: George Washington Lambert's Chesham Street (1910). The painting shows an upper-class male patient lifting his shirt to reveal a muscular torso for examination by the doctor in the scene and the viewers outside it. The subject of a medical examination, I argue, legitimised the scrutiny of exposed male flesh and offered an opportunity for sensual pleasure between men. By way of a comparison with other portraits of the artist from around the same period, I interpret Chesham Street as a patient self-portrait, which reveals the artist's dual personalities of bohemian artist and Australian boxer: two personae that did not combine seamlessly, as revealed by the composite nature of the patient in Chesham Street. From a discussion of the artist as patient, I move to an analysis of other self-portraits by Lambert in which the artist is shown flexing his muscles, especially in the context of his passion for boxing. I consider how these portraits serve as complex inscriptions of illness and health and how this relates to the experience of living and working as an Australian expatriate artist in London in the early twentieth century. PMID:23349514

  2. Speedup and fracturing of George VI Ice Shelf, Antarctic Peninsula

    NASA Astrophysics Data System (ADS)

    Holt, T. O.; Glasser, N. F.; Quincey, D. J.; Siegfried, M. R.

    2013-01-01

    George VI Ice Shelf (GVIIS) is located on the Antarctic Peninsula, a region where several ice shelves have undergone rapid breakup in response to atmospheric and oceanic warming. We use a combination of optical (Landsat), radar (ERS 1/2 SAR) and laser altimetry (GLAS) datasets to examine the response of GVIIS to environmental change and to offer an assessment on its future stability. The spatial and structural changes of GVIIS (ca. 1973 to ca. 2010) are mapped and surface velocities are calculated at different time periods (InSAR and optical feature tracking from 1989 to 2009) to document changes in the ice shelf's flow regime. Surface elevation changes are recorded between 2003 and 2008 using repeat track ICESat acquisitions. We note an increase in fracture extent and distribution at the south ice front, ice-shelf acceleration towards both the north and south ice fronts and spatially varied negative surface elevation change throughout, with greater variations observed towards the central and southern regions of the ice shelf. We propose that whilst GVIIS is in no imminent danger of collapse, it is vulnerable to on-going atmospheric and oceanic warming and is more susceptible to breakup along its southern margin in ice preconditioned for further retreat.

  3. Speedup and fracturing of George VI Ice Shelf, Antarctic Peninsula

    NASA Astrophysics Data System (ADS)

    Holt, T. O.; Glasser, N. F.; Quincey, D. J.; Siegfried, M. R.

    2013-05-01

    George VI Ice Shelf (GVIIS) is located on the Antarctic Peninsula, a region where several ice shelves have undergone rapid breakup in response to atmospheric and oceanic warming. We use a combination of optical (Landsat), radar (ERS 1/2 SAR) and laser altimetry (GLAS) datasets to examine the response of GVIIS to environmental change and to offer an assessment on its future stability. The spatial and structural changes of GVIIS (ca. 1973 to ca. 2010) are mapped and surface velocities are calculated at different time periods (InSAR and optical feature tracking from 1989 to 2009) to document changes in the ice shelf's flow regime. Surface elevation changes are recorded between 2003 and 2008 using repeat track ICESat acquisitions. We note an increase in fracture extent and distribution at the south ice front, ice-shelf acceleration towards both the north and south ice fronts and spatially varied negative surface elevation change throughout, with greater variations observed towards the central and southern regions of the ice shelf. We propose that whilst GVIIS is in no imminent danger of collapse, it is vulnerable to ongoing atmospheric and oceanic warming and is more susceptible to breakup along its southern margin in ice preconditioned for further retreat.

  4. George M. Low Trophy: NASA's quality and excellence award

    NASA Technical Reports Server (NTRS)

    1991-01-01

    NASA's major goal is the preservation of America's position as a leader in the aerospace industry. To maintain that status, it is crucial that the products and services we depend upon from NASA contractors, subcontractors, and suppliers meet the highest quality standards to ensure the space program's success. The George M. Low Trophy: NASA's Quality and Excellence Award is the result of NASA's desire to encourage continuous improvement and Total Quality Management (TQM) in the aerospace industry and is awarded to members of NASA's contractor community that have demonstrated sustained excellence, customer orientation, and outstanding achievements in a Total Quality Management (TQM) environment. The purpose in presenting this award is to increase public awareness of the importance of quality and productivity to the nation's aerospace industry and the nation's leadership position overall; encourage domestic business to continuously pursue efforts that enhance quality and increase productivity which will strengthen the nation's competitiveness in the international arena; and provide a forum for sharing the successful techniques and strategies used by applicants with other American organizations. Awards to Rockwell International and Marotta Scientific Controls, Inc. are announced and discussed.

  5. Structure of the dimerization domain of DiGeorge critical region 8

    SciTech Connect

    Senturia, R.; Faller, M.; Yin, S.; Loo, J.A.; Cascio, D.; Sawaya, M.R.; Hwang, D.; Clubb, R.T.; Guo, F.

    2010-09-27

    Maturation of microRNAs (miRNAs, {approx}22nt) from long primary transcripts [primary miRNAs (pri-miRNAs)] is regulated during development and is altered in diseases such as cancer. The first processing step is a cleavage mediated by the Microprocessor complex containing the Drosha nuclease and the RNA-binding protein DiGeorge critical region 8 (DGCR8). We previously reported that dimeric DGCR8 binds heme and that the heme-bound DGCR8 is more active than the heme-free form. Here, we identified a conserved dimerization domain in DGCR8. Our crystal structure of this domain (residues 298-352) at 1.7 {angstrom} resolution demonstrates a previously unknown use of a WW motif as a platform for extensive dimerization interactions. The dimerization domain of DGCR8 is embedded in an independently folded heme-binding domain and directly contributes to association with heme. Heme-binding-deficient DGCR8 mutants have reduced pri-miRNA processing activity in vitro. Our study provides structural and biochemical bases for understanding how dimerization and heme binding of DGCR8 may contribute to regulation of miRNA biogenesis.

  6. Closing the Door on Afterschool Programs: An Analysis of How the Proposed Cut to the 21st Century Community Learning Centers Program Will Affect Children and Families in Every State.

    ERIC Educational Resources Information Center

    Afterschool Alliance, Washington, DC.

    The After-School Alliance assessed the impact of a $400 million cut to the 21st Century Community Learning Centers program proposed by President George W. Bush for fiscal year 2004. The assessment determined the effect the proposed cut would have on the availability of after-school programs in each of the 50 states and the District of Columbia.…

  7. Identification and Characterization of Zebrafish SULT1 ST9, SULT3 ST4, and SULT3 ST5

    PubMed Central

    Mohammed, Yasir I.; Kurogi, Katsuhisa; Shaban, Amani Al; Xu, Zheng; Liu, Ming-Yih; Williams, Frederick E.; Sakakibara, Yoichi; Suiko, Masahito; Bhuiyan, Shakhawat; Liu, Ming-Cheh

    2012-01-01

    By searching the GenBank database, we identified sequences encoding three new zebrafish cytosolic sulfotransferases (SULTs). These three new zebrafish SULTs, designated SULT1 ST9, SULT3 ST4, and SULT3 ST5, were cloned, expressed, purified, and characterized. SULT1 ST9 appeared to be mostly involved in the metabolism and detoxification of xenobiotics such as β-naphthol, β-naphthylamine, caffeic acid and gallic acid. SULT3 ST4 showed strong activity toward endogenous compound such as dehydroepiandrosterone (DHEA), pregnenolone, and 17β-estradiol. SULT3 ST5 showed weaker, but significant, activities toward endogenous compounds such as DHEA and corticosterone, as well as xenobiotics including mestranol, β-naphthylamine, β-naphthol, and butylated hydroxyl anisole (BHA). pH-dependency and kinetic constants of these three enzymes were determined with DHEA, β-naphthol, and 17β-estradiol as substrates. Reverse transcription-polymerase chain reaction (RT-PCR) was performed to examine the expression of these three new zebrafish SULTs at different developmental stages during embryogenesis, through larval development, and on to maturity. PMID:22360938

  8. Thermal surveillance of active volcanoes using the LANDSAT-1 data collection system. Part 3: Heat discharge from Mount St. Helens, Washington

    NASA Technical Reports Server (NTRS)

    Friedman, J. D.; Frank, D. (Principal Investigator)

    1977-01-01

    The author has identified the following significant results. Two thermal anomalies, A at 2740 m altitude on the north slope, and B between 2650 and 2750 m altitude on the southwest slope at the contact of the dacite summit dome of Mount St. Helens, Washington were confirmed by aerial infrared scanner surveys between 1971 and 1973. LANDSAT 1 data collection platform 6166, emplaced at site B anomaly, transmitted 482 sets of temperature values in 1973 and 1974, suitable for estimating the differential radiatin emission as 84 W/sq m, approximately equivalent to the Fourier conductive flux of 89 W/sq m in the upper 15 cm below the surface. The differential geothermal flux, including heat loss via evaporation and convection, was estimated at 376 W/sq m. Total energy yield of Mount St. Helens probably ranges between 0.1 and 0.4 x 10 to the 6th power W.

  9. The influence of beta-adrenoceptor blockers with and without intrinsic sympathomimetic activity on heart rate, arrhythmias and ST-T segments, using ambulatory electrocardiography.

    PubMed Central

    Northcote, R J; Ballantyne, D

    1988-01-01

    1. Ambulatory electrocardiography was used to compare the effects of propranolol and pindolol on symptoms, heart rate, arrhythmias and ST segments. Seventeen males (mean age 54 years) with a diagnosis of chronic stable angina pectoris (New York Heart Association Class II-III) were studied. Patients were treated on a double-blind cross-over basis with propranolol 80 mg three times daily or pindolol 5 mg three times daily for 14 days each. During the last 48 h of each treatment period ambulatory electrocardiography was performed. 2. Propranolol resulted in a significantly lower mean hourly, mean 24 h and minimum heart rate. Likewise propranolol caused a lower mean daytime and nocturnal heart rate. There was no significant difference in the frequency of angina between the treatments. The number of episodes of ST segment depression was not significantly different between the two drugs, although there was a trend in favour of propranolol. 3. Both the mean 24 h ST level and the maximum ST segment depression were lower during treatment with pindolol. Propranolol was associated with a total of 117 nocturnal pauses or episodes of asystole ranging in length from 1.5 to 2.8 s. During treatment with pindolol only one such period occurred. The number of premature ventricular contractions occurring during treatment with pindolol (1316 beats) was less than on propranolol (2010) and the mean hourly frequency of premature ventricular contractions was significantly lower during pindolol administration. 4. Pindolol is not significantly different from propranolol in the control of symptomatic and asymptomatic myocardial ischaemia and is associated with fewer premature ventricular contractions. However, there is no advantage in using pindolol in chronic stable angina. PMID:3358881

  10. IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice

    PubMed Central

    Li, Dong; Guabiraba, Rodrigo; Besnard, Anne-Gaëlle; Komai-Koma, Mousa; Jabir, Majid S.; Zhang, Li; Graham, Gerard J.; Kurowska-Stolarska, Mariola; Liew, Foo Y.; McSharry, Charles; Xu, Damo

    2014-01-01

    Background The initiation and regulation of pulmonary fibrosis are not well understood. IL-33, an important cytokine for respiratory diseases, is overexpressed in the lungs of patients with idiopathic pulmonary fibrosis. Objectives We aimed to determine the effects and mechanism of IL-33 on the development and severity of pulmonary fibrosis in murine bleomycin-induced fibrosis. Methods Lung fibrosis was induced by bleomycin in wild-type or Il33r (St2)−/− C57BL/6 mice treated with the recombinant mature form of IL-33 or anti–IL-33 antibody or transferred with type 2 innate lymphoid cells (ILC2s). The development and severity of fibrosis was evaluated based on lung histology, collagen levels, and lavage cytology. Cytokine and chemokine levels were quantified by using quantitative PCR, ELISA, and cytometry. Results IL-33 is constitutively expressed in lung epithelial cells but is induced in macrophages by bleomycin. Bleomycin enhanced the production of the mature but reduced full-length form of IL-33 in lung tissue. ST2 deficiency, anti–IL-33 antibody treatment, or alveolar macrophage depletion attenuated and exogenous IL-33 or adoptive transfer of ILC2s enhanced bleomycin-induced lung inflammation and fibrosis. These pathologic changes were accompanied, respectively, by reduced or increased IL-33, IL-13, TGF-β1, and inflammatory chemokine production in the lung. Furthermore, IL-33 polarized M2 macrophages to produce IL-13 and TGF-β1 and induced the expansion of ILC2s to produce IL-13 in vitro and in vivo. Conclusions IL-33 is a novel profibrogenic cytokine that signals through ST2 to promote the initiation and progression of pulmonary fibrosis by recruiting and directing inflammatory cell function and enhancing profibrogenic cytokine production in an ST2- and macrophage-dependent manner. PMID:24985397

  11. Recolonization of gravel habitats on Georges Bank (northwest Atlantic)

    USGS Publications Warehouse

    Collie, J.S.; Hermsen, J.M.; Valentine, P.C.

    2009-01-01

    Gravel habitats on continental shelves around the world support productive fisheries but are also vulnerable to disturbance from bottom fishing. We conducted a 2-year in situ experiment to measure the rate of colonization of a gravel habitat on northern Georges Bank in an area closed to fishing (Closed Area II) since December 1994. Three large (0.25 m2) sediment trays containing defaunated pebble gravel were deployed at a study site (47 m water depth) in July 1997 and recovered in June 1999. The undersides of the tray lids positioned 56 cm above the trays served as settlement panels over the same time period. We observed rapid colonization of the gravel substrate (56 species) and the settlement panels (35 species), indicating that colonization of gravel in this region is not limited by the supply of colonists. The species composition of the taxa found in the trays was broadly similar to that we collected over a 10-year period (1994-2004) in dredge samples from gravel sediments at the same site. The increase in abundance of animals in the gravel colonization trays was rapid and reached a level in 2 years that took 4.5 years to achieve in the surrounding gravel sediments once fishing had stopped, based on data from dredge sampling at this site. The increase in biomass of animals found in the sediment trays paralleled the trend of biomass increase observed in dredge samples over the same period (1997-1999) but was lower in value. These data suggest that after rapid initial increase in abundance of organisms, succession proceeded by increasing individual body size. A comparison of settlement panel and tray faunas revealed that the mean biomass of structure-forming epifauna (sponges, bryozoans, anemones, hydroids, colonial tube worms) on the panels was 8 times that found on the trays. Structure-forming taxa constituted 29% of the mean biomass of the panel fauna but only 5.5% of the tray fauna. By contrast, the mean biomass of scavengers (crabs, echinoderms, nudibranchs

  12. Recolonization of gravel habitats on Georges Bank (northwest Atlantic)

    NASA Astrophysics Data System (ADS)

    Collie, Jeremy S.; Hermsen, Jerome M.; Valentine, Page C.

    2009-09-01

    Gravel habitats on continental shelves around the world support productive fisheries but are also vulnerable to disturbance from bottom fishing. We conducted a 2-year in situ experiment to measure the rate of colonization of a gravel habitat on northern Georges Bank in an area closed to fishing (Closed Area II) since December 1994. Three large (0.25 m 2) sediment trays containing defaunated pebble gravel were deployed at a study site (47 m water depth) in July 1997 and recovered in June 1999. The undersides of the tray lids positioned 56 cm above the trays served as settlement panels over the same time period. We observed rapid colonization of the gravel substrate (56 species) and the settlement panels (35 species), indicating that colonization of gravel in this region is not limited by the supply of colonists. The species composition of the taxa found in the trays was broadly similar to that we collected over a 10-year period (1994-2004) in dredge samples from gravel sediments at the same site. The increase in abundance of animals in the gravel colonization trays was rapid and reached a level in 2 years that took 4.5 years to achieve in the surrounding gravel sediments once fishing had stopped, based on data from dredge sampling at this site. The increase in biomass of animals found in the sediment trays paralleled the trend of biomass increase observed in dredge samples over the same period (1997-1999) but was lower in value. These data suggest that after rapid initial increase in abundance of organisms, succession proceeded by increasing individual body size. A comparison of settlement panel and tray faunas revealed that the mean biomass of structure-forming epifauna (sponges, bryozoans, anemones, hydroids, colonial tube worms) on the panels was 8 times that found on the trays. Structure-forming taxa constituted 29% of the mean biomass of the panel fauna but only 5.5% of the tray fauna. By contrast, the mean biomass of scavengers (crabs, echinoderms, nudibranchs

  13. In vitro toxicity and antidiabetic activity of a newly developed polyherbal formulation (MAC-ST/001) in streptozotocin-induced diabetic Wistar rats.

    PubMed

    Yadav, Deepak; Chaudhary, Anis Ahmad; Garg, Veena; Anwar, Mohammad Faiyaz; Rahman, Md Mahfooz-ur; Jamil, Sayed Sakir; Khan, Haider Ali; Asif, Mohd

    2013-06-01

    The present study was designed to investigate the hypoglycemic effect of an aqueous extract of MAC-ST/001 (a new polyherbal formulation) which was given once daily to rats at different doses. The animals were divided into diabetic and nondiabetic control groups. The duration of each experiment lasted from 1 week to 1 month, and the results were compared with that of the standard hypoglycemic drug glibenclamide (10 mg/kg), which was given once daily. In this study, biochemical and histopathological parameters were studied in streptozotacin (STZ) (single intraperitoneal injection of 55 mg/kg)-induced diabetic rats. The diabetic rats showed a significant (p < 0.05 and p < 0.01) decrease in their body weight and serum amylase with marked elevation in blood glucose, serum cholesterol, blood urea nitrogen, creatinine, alkaline phosphatase, and serum transaminases (AST and ALT) after 1 week till the 28th day of diabetes. Cytotoxicity of MAC-ST/001 formulation was also studied on C2C12, 3T3-L1, and HepG2 cells through MTT assay. Histological examination of the liver and pancreas of normal control, diabetic control, and drug-treated rats revealed significant results. Finally, it was concluded that administration of this MAC-ST/001 extract reversed most blood and tissue changes caused by STZ-induced diabetes in rats. PMID:23053765

  14. Georges Marinesco (1863-1938): neurologist, neurohistologist and neuropathologist.

    PubMed

    Catala, M; Poirier, J

    2012-01-01

    Gheorghe Marinescu (Georges Marinesco, in French) is a Romanian physician, founder of the School of Neurology in that country. He begins his medical studies in Bucharest, then has the opportunity to reach Paris and join the School of Neurology in La Salpêtrière Hospital, lead by Jean-Martin Charcot. This trip will forever imprint the mind of Marinescu, a great friend of France, a respectful student of Charcot and a friendly colleague of many Parisian neurologists. Marinescu's works are multiple and very important. He describes the succulent hand in syringomyelia and the palmar-jaw reflex. Marinescu is also one of the first to use the cinema for medical purposes. His work as an anatomo-clinician, a method developed by Charcot, is important. We denote the description of the locus niger affected by tuberculosis in a case of parkinsonism (this description paving Etienne Brissaud's way to highlight the anatomical origin of Parkinson's disease), the original clinical description of Marinesco-Sjögren syndrome, and that of medullomyoblastoma. Marinescu is also a famous neurocytologist as evidenced by his work, La Cellule Nerveuse, published in 1909. The first volume of the book is devoted to the aspects of the normal nervous tissue: the neurofibrillar network, the chromatophilic elements, and the paranucleolar corpuscles (now known as Marinescu's bodies). The second volume of the book is almost related to features revealed by experimental lesions: chromatolysis and neuronophagia. Furthermore, Marinescu describes with Oscar Blocq, small nodules than are now regarded as the first description of senile plaques. PMID:23303009

  15. Neurosurgical Work during the Napoleonic Wars: George James Guthrie's Experience.

    PubMed

    Roux, Franck-Emmanuel

    2016-01-01

    Involved in what is still considered, along with the two world wars of the 20th century, as one of the major conflicts in Europe, George James Guthrie (1785-1856) was the most famous English army surgeon of the Napoleonic wars. After treating the injured throughout the Peninsular Campaign (1808-1814), in 1815 and then in 1842 he published two major books dealing with cranial and brain injuries, among other topics. In these books, we can find, for example, an early description of the plantar reflex further described by Joseph Babinsky, accurate descriptions of the clinical signs of intracranial hypertension, and details of the physiopathology of subdural and epidural haematomas. Skull fractures are also discussed intensively, along with the indications for trepanation, a much-debated issue at the turn of the 19th century. The dura was often the limit of the surgical field for Guthrie. Nevertheless, he tried to rationalize the use of trepanation and favoured its use in two main cases: in cases of depressed skull bones, jammed bone fragments or debris irritating the dura or the brain and in cases of life-threatening cerebral compression caused by supposed blood clots. In their works, Guthrie and his contemporaries did not address neurosurgery in the modern sense of the word, but rather 'cranial surgery' in most cases. Guthrie, who saw so many patients with brain injuries and amputations, failed to understand that cerebral functions could be localized to the cortex and neglected to describe the phantom limb phenomenon, as did most of his contemporaries. PMID:27035714

  16. Silas Weir Mitchell and "The Strange Case of George Dedlow".

    PubMed

    Kline, David G

    2016-07-01

    It has been said of Silas Weir Mitchell (1829-1914) that as a young man he was first among the physiologists of his day, in middle age first among physicians, and as an older man, one of the most noted novelists of his country. Mitchell's novels were written in his later life as a means to avoid boredom during lengthy summer vacations that were the norm for that time among the affluent members of Philadelphia society. These novels were criticized by some because of poor plots, which in some instances failed to move along, or for text that offered a stereotyped depiction of genteel society and the effects that war or personal disaster had on the characters' behavior The criticism came despite the fact that all critics agreed that Mitchell's portrayals of psychopathology in his fictional characters was unique and accurate. However, in his 30s, Mitchell had written and by chance had published a fictional short story that not only transcended such criticisms but became immensely popular. "The Strange Case of George Dedlow" portrays a union officer who was not a physician but who had some medical background and who sustained a series of war wounds leading to severe nerve pain, the author's first description of causalgia, multiple amputations, and the psychological as well as physical symptoms of phantom limb syndrome. The protagonist tells of his torments in the first person in a very engaging fashion. Thus, long before he began writing his, at that time, acclaimed novels in the 1880s, Mitchell wrote a piece of fiction that combines accurate and very important medical observations with fiction of great historical interest. The following rendering of this now classic short story includes selected quotes and some interpretation and is perhaps appropriate for this year, 2 years after the centenary year of his death in 1914. PMID:27364258

  17. 6. VIEW FROM CHESTNUT ST. (upper), WALNUT ST. (lower) THIRD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. VIEW FROM CHESTNUT ST. (upper), WALNUT ST. (lower) THIRD ST. (right) AND FOURTH ST. (left), SHOWING CARPENTERS HALL, FIRST BANK OF U.S. AND SECOND BANK OF U.S. - Independence National Historical Park, Walnut, Sixth, Chestnut & Second Streets, Philadelphia, Philadelphia County, PA

  18. Pedagogical progeniture or tactical translation? George Fordyce's additions and modifications to William Cullen's philosophical chemistry--Part I.

    PubMed

    Taylor, Georgette

    2014-02-01

    This article contributes to a growing body of research on the dissemination, dispersion or diffusion of scientific knowledge via pedagogical networks. By examining students' handwritten lecture notes, I compare the eighteenth-century chemistry lectures given by William Cullen (1710-1790) at Glasgow and Edinburgh Universities with those of his one-time student George Fordyce (1736-1802), in London, at first privately and then as part of the medical education of physicians at St. Thomas's Hospital. Part I examines the broad structure of Cullen's and Fordyce's courses, comparing both course content and pedagogical approaches to ask how far knowledge flowed directly 'downstream,' and the extent to which it was transformed, translated or transmuted in the process of transmission. Part II (forthcoming) will approach the affinity theories of Cullen and Fordyce in greater depth, revealing the dynamics of knowledge transfer. The results shed light on the transmission of knowledge and skills between master and student, and reflect on whether Fordyce can be better described as Cullen's pedagogical progeny, or less straightforwardly as a tactical translator. PMID:25241503

  19. Mount St. Helens

    NASA Technical Reports Server (NTRS)

    2005-01-01

    This Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) image of Mount St. Helens was captured one week after the March 8, 2005, ash and steam eruption, the latest activity since the volcano's reawakening in September 2004. The new lava dome in the southeast part of the crater is clearly visible, highlighted by red areas where ASTER's infrared channels detected hot spots from incandescent lava. The new lava dome is 155 meters (500 feet) higher than the old lava dome, and still growing.

    With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER images Earth to map and monitor the changing surface of our planet.

    ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.

    The broad spectral coverage and high spectral resolution of ASTER provides scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance.

    The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

    Size: 21.9 by 24.4 kilometers (13.6 by 15.1 miles) Location: 46.2 degrees North latitude, 122.2 degrees West longitude Orientation: North at top Image Data: ASTER bands 8, 3, and 1 Original Data Resolution

  20. Geochemical markers of soil anthropogenic contaminants in polar scientific stations nearby (Antarctica, King George Island).

    PubMed

    Prus, Wojciech; Fabiańska, Monika J; Łabno, Radosław

    2015-06-15

    The organic contamination of Antarctic soils and terrestrial sediments from nearby of five polar scientific stations on King George Island (Antarctica) was investigated. Gas chromatography-mass spectrometry (GC-MS) was applied to find composition of dichloromethane extracts of soil and terrestrial sediments. The presence of geochemical markers, such as n-alkanes, steranes, pentacyclic triterpenoids, and alkyl PAHs, their distribution types, and values of their ratios indicates the predominating source of organic fossil fuels and products of their refining rather than from the natural Antarctic environment. Fossil fuel-originated compounds well survived in conditions of Antarctic climate over long times thus enabling to characterize geochemical features of source fossil fuel identified as petroleum expelled from kerogen II of algal/bacterial origins deposited in sub-oxic conditions and being in the middle of catagenesis. Both microbial activity and water leaching play an important role in degradation of terrestrial oil spills in the Antarctica climate, and petroleum alteration occurs lowly over long periods of time. Synthetic anthropogenic compounds found in terrestrial Antarctica sediments included diisopropylnaphthalenes, products of their sulfonates degradation in paper combustion, and organophosporus compounds used as retardants and plasticizers. PMID:25770449

  1. Occurrence of organochlorine pesticides in the environmental matrices from King George Island, west Antarctica.

    PubMed

    Zhang, Qinghua; Chen, Zhaojing; Li, Yingming; Wang, Pu; Zhu, Chaofei; Gao, Guanjun; Xiao, Ke; Sun, Huizhong; Zheng, Shucheng; Liang, Yong; Jiang, Guibin

    2015-11-01

    Antarctica is considered as a final sink of many persistent organic pollutants (POPs). This work aims to investigate the levels, distributions and potential sources of organochlorine pesticides (OCPs) with HRGC/HRMS technique. Twenty-three OCPs were measured in various environmental matrices from King George Island, west Antarctica. The total concentrations (Σ23OCPs) were at quite low levels, ranging 93.6-1260 pg g(-1) dry weight (dw) in soil and sediment, 223-1053 pg g(-1) dw in moss and 373-812 pg g(-1) dw in lichen. Hexachlorobenzene (HCB), dichloro-diphenyl-trichloroethane (DDT) and its metabolites (especially p,p'-DDE) and hexachlorocyclohexanes (HCHs) were the main contaminants in all samples. Lower α-HCH/γ-HCH and higher p,p'-DDE/p,p'-DDT ratios compared with the technical products indicated long-range atmospheric transport (LRAT) of recent lindane and aged technical DDT. Significant dependence of many OCPs concentrations on total organic carbon (TOC) was observed. Apart from LRAT, local biotic activities could also contribute and influence the spatial distribution of the contaminants. PMID:26162333

  2. SAPHO osteomyelitis and sarcoid dermatitis in a patient with DiGeorge syndrome.

    PubMed

    Jyonouchi, Harumi; Lien, Kenneth W; Aguila, Helen; Spinnato, Gaetano G; Sabharwal, Sanjeev; Pletcher, Beth A

    2006-06-01

    We report the development and spontaneous resolution of annular erythematous skin lesions consistent with sarcoid dermatitis in a child with DiGeorge syndrome (DGS) carrying the 22q11.2 microdeletion. The skin lesion developed after she was treated with isoniazid (INH) following exposure to active tuberculosis (TB). After resolution of the skin lesions, this child developed sterile hyperplastic osteomyelitis consistent with SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) osteomyelitis in her right mandible triggered by an odontogenic infection. This child had congenital heart disease, dysmorphic facies, recurrent sinopulmonary infection, gastroesophageal reflux disease, scoliosis, reactive periostitis, and developmental delay. She had a low CD4 and CD8 T cell count with a normal 4/8 ratio, but normal cell proliferation and T cell cytokine production in response to mitogens. When she was presented with sterile osteomyelitis of right mandible, she revealed polyclonal hypergammaglobulinemia with elevated erythrocyte sedimentation rate (ESR)/angiotensin converting enzyme (ACE) levels, but negative CRP. Autoimmune and sarcoidosis workup was negative. Inflammatory parameters gradually normalized following resolution of odontogenic infection and with the use of non-steroidal anti-inflammatory drugs (NSAIDs). The broad clinical spectrum of DGS is further expanded with the development of autoimmune and inflammatory complications later in life. This case suggests that patients with the DGS can present with unusual sterile inflammatory lesions triggered by environmental factors, further broadening the clinical spectrum of this syndrome. PMID:16491384

  3. Georges Lemaître: The Priest Who Invented the Big Bang

    NASA Astrophysics Data System (ADS)

    Lambert, Dominique

    This contribution gives a concise survey of Georges Lemaître works and life, shedding some light on less-known aspects. Lemaître is a Belgian catholic priest who gave for the first time in 1927 the explanation of the Hubble law and who proposed in 1931 the "Primeval Atom Hypothesis", considered as the first step towards the Big Bang cosmology. But the scientific work of Lemaître goes far beyond Physical Cosmology. Indeed, he contributed also to the theory of Cosmis Rays, to the Spinor theory, to Analytical mechanics (regularization of 3- Bodies problem), to Numerical Analysis (Fast Fourier Transform), to Computer Science (he introduced and programmed the first computer of Louvain),… Lemaître took part to the "Science and Faith" debate. He defended a position that has some analogy with the NOMA principle, making a sharp distinction between what he called the "two paths to Truth" (a scientific one and a theological one). In particular, he never made a confusion between the theological concept of "creation" and the scientific notion of "natural beginning" (initial singularity). Lemaître was deeply rooted in his faith and sacerdotal vocation. Remaining a secular priest, he belonged to a community of priests called "The Friends of Jesus", characterized by a deep spirituality and special vows (for example the vow of poverty). He had also an apostolic activity amongst Chinese students.

  4. The life of concepts: Georges Canguilhem and the history of science.

    PubMed

    Schmidgen, Henning

    2014-01-01

    Twelve years after his famous Essay on Some Problems Concerning the Normal and the Pathological (1943), the philosopher Georges Canguilhem (1904-1995) published a book-length study on the history of a single biological concept. Within France, his Formation of the Reflex Concept in the Seventeenth and Eighteenth Centuries (1955) contributed significantly to defining the "French style" of writing on the history of science. Outside of France, the book passed largely unnoticed. This paper re-reads Canguilhem's study of the reflex concept with respect to its historiographical and epistemological implications. Canguilhem defines concepts as complex and dynamic entities combining terms, definitions, and phenomena. As a consequence, the historiography of science becomes a rather complex task. It has to take into account textual and contextual aspects that develop independently of individual authors. In addition, Canguilhem stresses the connection between conceptual activities and other functions of organic individuals in their respective environments. As a result, biological concepts become tied to a biology of conceptual thinking, analogical reasoning, and technological practice. The paper argues that this seemingly circular structure is a major feature in Canguilhem's philosophical approach to the history of the biological sciences. PMID:25515359

  5. Harry Stack Sullivan Colloquium: George Herbert Mead and Harry Stack Sullivan: an unfinished synthesis.

    PubMed

    Cottrell, L S

    1978-05-01

    HOW DO YOU create a new self? However he may phrase this question, it is a central theoretical and practical concern of the therapist every time he confronts a client who comes to him for help. What are the processes out of which the human self emerges? However he may phrase the question, it is a central concern of the social psychologist. The obvious convergence of interests indicated by these two questions should occasion no surprise among students of Sullivan and Mead. What perhaps should be surprising is that an effective synthesis of their theories has progressed no further than it has to date. My remarks today are based on the conviction that a more adequate psychiatric theory and practice and a more complete social psychological theory and research program depend on such a synthesis. Behavioral scientists concerned with the development of a truly interactionist social psychology are, I believe, generally agreed that George Herbert Mead (1863-1931), philosopher and social psychologist, and Harry Stack Sullivan (1892-1949), psychiatrist and social psychologist, have laid conceptual foundations upon which such a discipline can be erected. Now a vast assortment of activities is tagged as social psychology and its boundaries are, indeed, difficult to draw. However, for our present purposes we can define its focus as the study of the processes and products of inter- and intrapersonal and inter- and intragoup interaction, let the boundaries fall where they will. PMID:349586

  6. Trace element contamination and availability in the Fildes Peninsula, King George Island, Antarctica.

    PubMed

    Padeiro, Ana; Amaro, Eduardo; Dos Santos, Margarida M C; Araújo, Maria F; Gomes, Susana S; Leppe, Marcelo; Verkulich, Sergey; Hughes, Kevin A; Peter, Hans-Ulrich; Canário, João

    2016-06-15

    The Ardley Cove area (located on the Maxwell Bay shoreline, Fildes Peninsula, King George Island, Antarctica) is characterized not only by its high biodiversity, but also by a high density of scientific stations, making it potentially one of the most impacted areas of Antarctica. In order to assess the source, contamination levels, distribution and availability of several trace elements (Cr, Ni, Cu, Zn, As, Pb, Cd and Hg) in and around Maxwell Bay, soil and seawater samples were collected. Soil samples were also collected in the study reference site near the Bellingshausen Dome area, as it lies far from centers of human activity and associated infrastructure. Enrichment factors (EFs) and sequential extractions were also used to assess the degree of contamination and availability of the trace elements under investigation. The results obtained in this study pointed to the existence of several contamination hotspots, mainly related to high levels of Zn, Pb, Cd, Cr and Ni. Comparison of the contaminant distribution patterns with data from earlier studies allowed the identification of anthropogenic sources. Use of the EF approach and sequential extractions confirmed these findings. In particular, higher extraction proportions were obtained for Zn and Pb (68 and 71%, respectively), which were also the same elements where the highest EFs were determined. The results obtained in this study clearly point to human impact on the natural environment in this region of Antarctica and we recommend the implementation of appropriate contamination control and remediation methods. PMID:27224418

  7. Assessing trace element contamination in Fildes Peninsula (King George Island) and Ardley Island, Antarctic.

    PubMed

    Amaro, Eduardo; Padeiro, Ana; Mão de Ferro, André; Mota, Ana Maria; Leppe, Marcelo; Verkulich, Sergey; Hughes, Kevin A; Peter, Hans-Ulrich; Canário, João

    2015-08-15

    King George Island, situated in the South Shetland Islands archipelago, is one of the most visited sites in Antarctica. This has contributed to a high density of scientific stations and shelters in the region, especially in Fildes Peninsula. In order to evaluate the natural and anthropogenic sources of trace elements (As, Cd, Cu, Zn, Pb and Hg) soil and moss samples were collected from different sites in January 2013. In general, the results revealed homogeneous concentrations (μgg(-)(1)) for each element in the majority of collected samples (As: 3.8±1.4; Cd: 0.4±0.9; Cu: 34±4; Zn: 115±13; Pb: 20±5; Hg; 0.011±0.009). However, some samples in specific areas of Fildes Bay showed the existence of local anthropogenic activities that have contributed to the enrichment of contaminants in soils and moss samples that correlated to one another (e.g. Pb: 1101μgg(-)(1)). Human presence is linked to examples of contamination and environmental perturbation, making essential the implementation of this type of study in order to understand and protect unique places in Antarctica. PMID:25982820

  8. How to boost soundscapes with tax breaks-On the application of Henry George's environmental economics to noise annoyance

    NASA Astrophysics Data System (ADS)

    Hehner, Cay

    2001-05-01

    The improvement of the characteristic soundscape in a given metropolitan area depends largely on a varied number of parameters not the least of which are economic. The way to sustain a large city not only economically responsible behavior patterns and activities are required, but ecologically viable ones as well. And, not coincidentally, if both patterns come into balance, a reduction of noise annoyance ensues. The cohesive set of measures that would provide the framework to ensure that the necessary economic activity is not antagonistic to (acoustic) ecology is provided by the US economist Henry George who advocated a comprehensive tax on land and all natural resources to replace eventually the bulk of all taxes checking production. New data will be provided in this paper to show the results of the application of a Georgist approach of eco-taxation to the improvement of sound quality and the reduction of noise annoyance.

  9. Processed seismic motion records from St. George, Utah earthquake of September 2, 1992, recorded at seismic stations in southern Nevada

    SciTech Connect

    Lum, P.K.; Honda, K.K.

    1993-04-01

    As part of the contract with the US Department of Energy, Nevada Field Office (DOE/NV), URS/John A. Blume & Associates, Engineers (URS/Blume) maintains a network of seismographs in southern Nevada to monitor the ground motion generated by the underground nuclear explosions (UNEs) at the Nevada Test Site (NTS). The seismographs are located in the communities surrounding the NTS and the Las Vegas valley. When these seismographs are not used for monitoring the UNE generated motions, a limited number of seismographs are maintained for monitoring motion generated by other than UNEs (e.g. motion generated by earthquakes, wind, blast). During the subject earthquake of September 2, 1992, a total of 16 of these systems recorded the earthquake motions. This report contains the recorded data.

  10. Structural and stratigraphic evolution of the East Georges Bank Basin, offshore Nova Scotia, Canada

    SciTech Connect

    Carswell, A.B. ); Koning, T. ); Hibbs, D.C. )

    1990-05-01

    The East Georges Bank Basin is located offshore Nova Scotia on the southeastern Canadian continental shelf. The basin covers 2.5 million ac and is one of the last undrilled basins in North America. The geological interpretation is almost entirely based on 16,000 km of seismic data over the basin. Pertinent well control is limited to 10 wells on the US portion of the Georges Bank (West Georges Bank Basin) and two wells on the Scotian shelf. Seismic-stratigraphic analysis of this data has led to a structural and stratigraphic model for the basin. The basin formed during the Triassic when the landmass of Pange began separating along rift zones. A prominent Paleozoic basement high, the Yarmouth Arch separated the East Georges Bank Basin from the West Georges Bank Basin and had a dominant influence on sedimentation until the Middle Jurassic. Early synrift sequences consist of lacustrine clastics and shales. Marine incursions began in the late Triassic resulting in massive salt deposits that reflect the restricted extent of the basin and the arid Triassic and Early Jurassic climate. Further continental separation during the Early Jurassic resulted in deposition of carbonates and evaporites followed by Middle Jurassic continental shelf carbonates and deltaic sands. During the Middle Jurassic, major growth faulting and halokinesis was initiated by progradation of the deltaic sands. Post Middle Jurassic continental spreading in combination with changing climatic conditions resulted in a steady decline of carbonate sedimentation and dominance of clastic deposition throughout the remaining history of the basin.

  11. MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome.

    PubMed

    Voss, Anne K; Vanyai, Hannah K; Collin, Caitlin; Dixon, Mathew P; McLennan, Tamara J; Sheikh, Bilal N; Scambler, Peter; Thomas, Tim

    2012-09-11

    DiGeorge syndrome, caused by a 22q11 microdeletion or mutation of the TBX1 gene, varies in severity greatly, even among monozygotic twins. Epigenetic phenomena have been invoked to explain phenotypic differences in individuals of identical genetic composition, although specific chromatin modifications relevant to DiGeorge syndrome are elusive. Here we show that lack of the histone acetyltransferase MOZ (MYST3/KAT6A) phenocopies DiGeorge syndrome, and the MOZ complex occupies the Tbx1 locus, promoting its expression and histone 3 lysine 9 acetylation. Importantly, DiGeorge syndrome-like anomalies are present in mice with homozygous mutation of Moz and in heterozygous Moz mutants when combined with Tbx1 haploinsufficiency or oversupply of retinoic acid. Conversely, a Tbx1 transgene rescues the heart phenotype in Moz mutants. Our data reveal a molecular mechanism for a specific chromatin modification of the Tbx1 locus intersecting with an environmental determinant, modeling variability in DiGeorge syndrome. PMID:22921202

  12. Pioneers of movement disorders: Georges Gilles de la Tourette.

    PubMed

    Krämer, H; Daniels, C

    2004-06-01

    Georges Albert Edouard Brutus Gilles de la Tourette (1857-1904), a French neurologist and pupil of Jean Martin Charcot at the Salpêtrière hospital in Paris, has gained common recognition through his description of the 'Maladie des Tics'. This complex neuropsychiatric disorder, later known as the 'Tourette's syndrome', nowadays is accepted as a specific entity of movement disorders. Gilles had started working under Charcot (1825-1893), the first physician to occupy a designated chair of neurology of neuropsychiatric history, in 1884. Then the Salpêtrière hospital was a centre of intensive research with an emphasis on hysteria and hypnosis. Tourette took an interest in hysteria, but also dedicated himself to various other neuropsychiatric disorders and to neuropathology. He published scientific works on epilepsia, neurasthenia and syphilitic myelitis. Although he devoted much time to his neuropsychiatric research and the publication of articles in medical journals, his career did not make significant progress, despite Charcot's unrestricted support. One reason was, that he disregarded questions, answers and problems, which were outside his interest fields. Hence, he was accused for having acquired an extremely filtered and one-sided knowledge. Also, his alienated and critical behaviour, which had not helped him to find many friends over the years, prevented him from professional promotion. In 1893 an assassination attempt on Gilles de la Tourette raised considerable public interest: Gilles was shot in his appartement in the Rue de l'Université 39 by a young woman, who had been his patient in the Salpêtrière and who claimed that she had been hypnotized without her agreement and thereby had lost her mental health. However, the patient was diagnosed with a disease nowadays called paranoid schizophrenia and therefore hypnosis was not attributed to any part of the disease. Due to episodes of melancholia and phases of delusions of grandeur and megalomania Gilles de

  13. Modern sedimentation patterns in Potter Cove, King George Island, Antarctica

    NASA Astrophysics Data System (ADS)

    Hass, H. Christian; Kuhn, Gerhard; Wölfl, Anne-Cathrin; Wittenberg, Nina; Betzler, Christian

    2013-04-01

    IMCOAST among a number of other initiatives investigates the modern and the late Holocene environmental development of south King George Island with a strong emphasis on Maxwell Bay and its tributary fjord Potter Cove (maximum water depth: about 200 m). In this part of the project we aim at reconstructing the modern sediment distribution in the inner part of Potter Cove using an acoustic ground discrimination system (RoxAnn) and more than136 ground-truth samples. Over the past 20 years the air temperatures in the immediate working area increased by more than 0.6 K (Schloss et al. 2012) which is less than in other parts of the West Antarctic Peninsula (WAP) but it is still in the range of the recovery of temperatures from the Little Ice Age maximum to the beginning of the 20th century. Potter Cove is a small fjord characterized by a series of moraine ridges produced by a tidewater glacier (Fourcade Glacier). Presumably, the farthest moraine is not much older than about 500 years (LIA maximum), hence the sediment cover is rather thin as evidenced by high resolution seismic data. Since a few years at least the better part of the tidewater glacier retreated onto the island's mainland. It is suggested that such a fundamental change in the fjord's physiography has also changed sedimentation patterns in the area. Potter Cove is characterized by silty-clayey sediments in the deeper inner parts of the cove. Sediments are coarser (fine to coarse sands and boulders) in the shallower areas; they also coarsen from the innermost basin to the mouth of the fjord. Textural structures follow the seabed morphology, i.e. small v-shaped passages through the moraine ridges. The glacier still produces large amounts of turbid melt waters that enter the cove at various places. We presume that very fine-grained sediments fall out from the meltwater plumes and are distributed by mid-depth or even bottom currents, thus suggesting an anti-estuarine circulation pattern. Older sediments that are

  14. St. Louis, Missouri

    NASA Technical Reports Server (NTRS)

    2007-01-01

    St. Louis is tucked in a bend of the Mississippi River, just south of the point at which the Illinois River joins the larger Mississippi, and where the Missouri River flows in from the west. Drainage patterns to the east, on the Illinois side, are highlighted with green vegetation. Meandering rivers in the verdant Ozark Plateau appear to the south and west.

    This true-color view from NASA's Multi-angle Imaging SpectroRadiometer (MISR) was taken with the instrument's downward looking (nadir) camera on October 15, 2005. The urban areas of greater St. Louis show up as grey-white, including nearby Kirkwood, Webster Groves, Clayton, University City, Ferguson, St. Ann, St. Charles, and East St. Louis. The region is home to nearly three million people.

    MISR was built and is managed by NASA's Jet Propulsion Laboratory, Pasadena, Calif., for NASA's Science Mission Directorate, Washington, DC. The Terra satellite is managed by NASA's Goddard Space Flight Center, Greenbelt, Md. JPL is a division of the California Institute of Technology.

  15. Expression and characterization of styrene monooxygenases of Rhodococcus sp. ST-5 and ST-10 for synthesizing enantiopure (S)-epoxides.

    PubMed

    Toda, Hiroshi; Imae, Ryouta; Komio, Tomoko; Itoh, Nobuya

    2012-10-01

    Styrene monooxygenase (StyA, SMOA)- and flavin oxidoreductase (StyB, SMOB)-coding genes of styrene-assimilating bacteria Rhodococcus sp. ST-5 and ST-10 were successfully expressed in Escherichia coli. Determined amino acid sequences of StyAs and StyBs of ST-5 and ST-10 showed more similarity with those of Pseudomonas than with self-sufficient styrene monooxygenase (StyA2B) of Rhodococcus. Recombinant enzymes were purified from E. coli cells as functional proteins, and their properties were characterized in detail. StyBs (flavin oxidoreductase) of strains ST-5 and ST-10 have similar enzymatic properties to those of Pseudomonas, but StyB of strain ST-10 exhibited higher temperature stability than that of strain ST-5. StyAs of strains ST-5 and ST-10 catalyzed the epoxidation of vinyl side-chain of styrene and its derivatives and produced (S)-epoxides from styrene derivatives and showed high stereoselectivity. Both StyAs showed higher specific activity on halogenated styrene derivatives than on styrene itself. Additionally, the enzymes could catalyze the epoxidation of short-chain 1-alkenes to the corresponding (S)-epoxides. Aromatic compounds including styrene, 3-chlorostyrene, styrene oxide, and benzene exhibited marked inhibition of SMO reaction, although linear 1-alkene showed no inhibition of SMO activity at any concentration. PMID:22258641

  16. The First Case Report in Italy of Di George Syndrome Detected by Noninvasive Prenatal Testing

    PubMed Central

    Rapacchia, Giuseppina; Lapucci, Cristina; Pittalis, Maria Carla; Youssef, Aly; Farina, Antonio

    2015-01-01

    Panorama Plus (Natera), a single-nucleotide polymorphism- (SNP-) based approach that relies on the identification of maternal and fetal allele distributions, allows the detection of common aneuploidies and also incorporates a panel of 5 microdeletions including Di George syndrome. We report here the first case of Di George syndrome detected by NIPT in Italy; blood was drawn at 12 weeks' gestation. The patient had an amniocentesis to confirm the diagnosis by MLPA (multiplex ligation-dependent probe amplification) and an ultrasound aimed to detect the features associated with the syndrome. A right aortic arch and suspect of thymus atrophy were detected, but not other severe malformations typical of the disease. The patient terminated the pregnancy at 17 weeks. NIPT allowed an early screening of Di George syndrome. As the patient was at low risk, it is likely that an ultrasound would have missed the condition. PMID:26346617

  17. Passive margins: U.S. Geological Survey Line 19 across the Georges Bank basin

    USGS Publications Warehouse

    Klitgord, Kim D.; Schlee, John S.; Grow, John A.

    1987-01-01

    Georges Bank is a shallow part of the Atlantic continental shelf southeast of New England (Emery and Uchupi, 1972, 1984). This bank, however, is merely the upper surface of several sedimentary basins overlying a block-faulted basement of igneous and metamorphic crystalline rock. Sedimentary rock forms a seaward-thickening cover that has accumulated in one main depocenter and several ancillary depressions, adjacent to shallow basement platforms of paleozoic and older crystalline rock. Georges Bank basin contains a thickness of sedimentary rock greater than 10 km, whereas the basement platforms that flank the basin are areas of thin sediment accumulation (less than 5 km).

  18. Stratigraphic reference section for Georges Bank Basin - depositional model for New England passive margin.

    USGS Publications Warehouse

    Poag, C.W.

    1982-01-01

    A multichannel seismic reflection profile (US Geological Survey line 19), calibrated with the COST G-1, COST G-2, and Shell Mohican I-100 wells, and seismic-sequence analysis shows that the chronostratigraphic and lithostratigraphic units and depositional history of the Georges Bank basin are similar to those of the Scotian basin. Tentative correlation between the Georges Bank basin sequences and those of the adjacent, deep N American basin suggests that the deep-sea facies were strongly influenced by depositional events on the shelf. Deposition in both areas has been sensitive to changes in sea level and the palaeoclimatic cycles.-Author

  19. Effects of Hurricane Georges on habitat use by captive-reared Hispaniolan Parrots (Amazona ventralis) released in the Dominican Republic

    USGS Publications Warehouse

    White, T.H., Jr.; Collazo, J.A.; Vilella, F.J.; Guerrero, S.A.

    2005-01-01

    We radio-tagged and released 49 captive-reared Hispaniolan Parrots (Amazona ventralis) in Parque Nacional del Este (PNE), Dominican Republic, during 1997 and 1998. Our primary objective was to develop a restoration program centered on using aviary-reared birds to further the recovery of the critically endangered Puerto Rican Parrot (A. vittata). Hurricane Georges made landfall over the release area on 22 September 1998 with sustained winds of 224 km/h, providing us with a unique opportunity to quantify responses of parrots to such disturbances. Quantitative data on such responses by any avian species are scarce, particularly for Amazona species, many of which are in peril and occur in hurricane-prone areas throughout the Caribbean. Mean home ranges of 18 parrots monitored both before and after the hurricane increased (P = 0.08) from 864 ha (CI = 689-1039 ha) pre-hurricane to 1690 ha (CI = 1003-2377 ha) post-hurricane. The total area traversed by all parrots increased > 300%, from 4884 ha pre-hurricane to 15,490 ha post-hurricane. Before Hurricane Georges, parrot activity was concentrated in coastal scrub, tall broadleaf forest, and abandoned agriculture (conucos). After the hurricane, parrots concentrated their activities in areas of tall broadleaf forest and abandoned conucos. Topographic relief, primarily in the form of large sinkholes, resulted in "resource refugia" where parrots and other frugivores foraged after the hurricane. Habitat use and movement patterns exhibited by released birds highlight the importance of carefully considering effects of season, topography, and overall size of release areas when planning psittacine restorations in hurricane-prone areas. ?? The Neotropical Ornithological Society.

  20. George Gershwin -- a case of new ways in neurosurgery as well as in the history of Western music.

    PubMed

    Gasenzer, Elena; Neugebauer, Edmund A M

    2014-06-01

    George Gershwin, the famous American composer, died in 1937 of a temporal lobe glioma. An emergency surgery was performed by R. Nafziger and W. E. Dandy. The case of George Gershwin indicates the beginning of a new era in music history as well as in the history of neurosurgery. PMID:24633986

  1. 76 FR 68210 - United States v. George's Foods, LLC, et al.; Public Comment and Response on Proposed Final Judgment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-03

    ... United States v. George's Foods, Inc., et. al., 76 FR 38419; and summaries of the terms of the proposed... that the Transaction would likely have the effect of enhancing George's incentive and ability to force... Judgment terminates upon motion by either the United States or the Defendants that the Defendants...

  2. Remembering Dr. George J. Apel, Jr: A Posthumous Tribute to an Innovative, Obscure Pioneer in Christian Higher Education

    ERIC Educational Resources Information Center

    Lumadue, Richard T.

    2007-01-01

    This paper is a belated tribute to George J. Apel, Jr., an innovative and obscure Christian higher educator. Peruse the name and subject indices of any and all books about Christian higher education, and nowhere will there appear even a reference to George J. Apel, Jr. Although Apel never finished high school or college, he was awarded an honorary…

  3. 77 FR 31684 - Withdrawal of Notice of Intent To Prepare an Environmental Impact Statement for the George Bush...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-29

    ... stating such on September 16, 2010 [75 FR 56653]. On January 3, 2012, the HAS sent a letter to the FAA... Statement for the George Bush Intercontinental Airport, Houston, TX AGENCY: Federal Aviation Administration... the George Bush Intercontinental Airport (IAH). The Houston Airport System (HAS), the sponsor of...

  4. Growing Pains from Rapid Growth: A Historical Case Study of George Fox University from 1983 to 2003

    ERIC Educational Resources Information Center

    Railsback, Gary L.

    2007-01-01

    This article is a historical case study of George Fox University (GFU) in Newberg, Oregon. Using organizational lifecycle as a theoretical framework, George Fox University had a long and delayed childhood in that it remained a small and struggling institution for most of the 20th century, and then experienced rapid growth in the late 1980s. This…

  5. Geoscience Education and Cognition Research at George Mason University

    NASA Astrophysics Data System (ADS)

    Mattietti, G. K.; Peters, E. E.; Verardo, S.

    2009-12-01

    Cognition research in Geoscience is the focus of a small group of faculty from the College of Science and the College of Education and Human Development at George Mason University. We approached this research when we were involved in an Institution-wide effort to assess critical thinking, one of the competencies mandated for evaluation by the State Council of Higher Education of Virginia. Our group started spontaneously and informally from personal interests and enthusiasm for what and how our students are learning about Geology and in general about science. We want to understand what our students bring to the course, their attitude towards science, their knowledge of the scientific enterprise and preconceived ideas—and what our students take away from the course, beyond the course content. We believe that, with the support of cognitive science, we can improve the learning experience and therefore enhance the learning outcomes for science and non-science majors alike. Our Institution offers introductory Physical and Historical Geology classes populated primarily by non-science-major undergraduates. Geology lectures range in size from 90 to over 220 students per session per semester, with laboratory sessions averaging 27 students per session. With this large student population, it is necessary to use research tools that give us valuable information about student cognition, while being efficient in terms of time use and logistics. Some examples of our work include critical readings on Geoscience topics, surveys on students’ understanding of science as a way of knowing, exercises with built-in self-efficacy assessments, and concept mapping. The common denominator among these tools is that they are calibrated to address one or more of the higher levels in the revised Bloom’s Taxonomy of the Cognitive Domain, which form a complex assessment of student learning processes. These tools, once refined, can provide us with a better view of how our students learn in

  6. Emerging ST121/agr4 community-associated methicillin-resistant Staphylococcus aureus (MRSA) with strong adhesin and cytolytic activities: trigger for MRSA pneumonia and fatal aspiration pneumonia in an influenza-infected elderly.

    PubMed

    Wan, T-W; Tomita, Y; Saita, N; Konno, K; Iwao, Y; Hung, W-C; Teng, L-J; Yamamoto, T

    2016-09-01

    The pathogenesis of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) pneumonia in influenza-infected elderly individuals has not yet been elucidated in detail. In the present study, a 92-year-old man infected with influenza developed CA-MRSA pneumonia. His CA-MRSA was an emerging type, originated in ST121/agr4 S. aureus, with diversities of Panton-Valentine leucocidin (PVL)(-)/spat5110/SCCmecV(+) versus PVL(+)/spat159((etc.))/SCCmec (-), but with common virulence potentials of strong adhesin and cytolytic activities. Resistance to erythromycin/clindamycin (inducible-type) and gentamicin was detected. Pneumonia improved with the administration of levofloxacin, but with the subsequent development of fatal aspiration pneumonia. Hence, characteristic CA-MRSA with strong adhesin and cytolytic activities triggered influenza-related sequential complications. PMID:27358743

  7. The St. Louis Motor

    ERIC Educational Resources Information Center

    Greenslade, Thomas B., Jr.

    2011-01-01

    The St. Louis Motor, invented in 1909, is unique among physics apparatus for being named for a geographical place rather than a physicist. The sturdy little device (Fig. 1) has never been out of production. Any older school or physics department that has not done a catastrophic housecleaning in the last 20 years will certainly have a small flock…

  8. 30 Cool Facts about Mount St. Helens

    USGS Publications Warehouse

    Driedger, Carolyn; Liz, Westby; Faust, Lisa; Frenzen, Peter; Bennett, Jeanne; Clynne, Michael

    2010-01-01

    Commemorating the 30th anniversary of the 1980 eruptions of Mount St. Helens 1-During the past 4,000 years, Mount St. Helens has erupted more frequently than any other volcano in the Cascade Range. 2-Most of Mount St. Helens is younger than 3,000 years old (younger than the pyramids of Egypt). 3-Some Native American names that refer to smoke at the volcano include- Lawala Clough, Low-We- Lat-Klah, Low-We-Not- Thlat, Loowit, Loo-wit, Loo-wit Lat-kla, and Louwala-Clough. 4-3,600 years ago-Native Americans abandoned hunting grounds devastated by an enormous eruption four times larger than the May 18, 1980 eruption. 5-1792-Captain George Vancouver named the volcano for Britain's ambassador to Spain, Alleyne Fitzherbert, also known as Baron St. Helens. 6-1975-U.S. Geological Survey geologists forecasted that Mount St. Helens would erupt again, 'possibly before the end of the century.' 7-March 20, 1980-A magnitude 4.2 earthquake signaled the reawakening of the volcano after 123 years. 8-Spring 1980-Rising magma pushed the volcano's north flank outward 5 feet per day. 9-Morning of May 18, 1980- The largest terrestrial landslide in recorded history reduced the summit by 1,300 feet and triggered a lateral blast. 10-Within 3 minutes, the lateral blast, traveling at more than 300 miles per hour, blew down and scorched 230 square miles of forest. 11-Within 15 minutes, a vertical plume of volcanic ash rose over 80,000 feet. 12-Afternoon of May 18, 1980-The dense ash cloud turned daylight into darkness in eastern Washington, causing streetlights to turn on in Yakima and Ritzville. 13-The volcanic ash cloud drifted east across the United States in 3 days and encircled Earth in 15 days. 14-Lahars (volcanic mudflows) filled rivers with rocks, sand, and mud, damaging 27 bridges and 200 homes and forcing 31 ships to remain in ports upstream. 15-The May 18, 1980 eruption was the most economically destructive volcanic event in U.S. history. 16-Small plants and trees beneath winter snow

  9. Chemistry of St. John's Wort: Hypericin and Hyperforin

    ERIC Educational Resources Information Center

    Vollmer, John J.; Rosenson, Jon

    2004-01-01

    The appeal as natural antidepressant is the major selling point of St. John's Wort, which is referred to as "Prozac from the plant kingdom". Hypericin and hyperforin, two major constituents with significant biological activity of St. John's Wort and which are complex molecules with unusual features, are examined.

  10. 78 FR 44927 - 101st Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-25

    ... From the Federal Register Online via the Government Publishing Office ARCTIC RESEARCH COMMISSION 101st Commission Meeting Notice is hereby given that the U.S. Arctic Research Commission will hold its... presentations concerning Arctic research activities The focus of the meeting will be Arctic research...

  11. Computerized Farm of the 21st Century.

    ERIC Educational Resources Information Center

    McGrann, James M.

    Advancement in computer technology comes at a time when agriculture is in transition from a production-oriented to a business-oriented activity and will require new skills and knowledge if farmers are to be prepared for the future. Electronic technology applications on 21st century commercial farms and ranches will include farm decision support…

  12. Reports from Science Mount St. Helens

    NASA Technical Reports Server (NTRS)

    Pollack, James B.

    1981-01-01

    The following reports describe extensive measurements of the properties of the gases and aerosols (particles) in the volcanic clouds produced by the eruptions of Mount St. Helens from March through August 1980. Volcanic material was first injected into the atmosphere on 27 March 1980. This material, as well as that introduced by subsequent eruptions during the next 2 months, was confined to the troposphere. On 18 May the first of several major explosions occurred in which some of the volcanic cloud penetrated well into the stratosphere. The nature of the volcanic activity at Mount St. Helens from the end of March through June was described.

  13. The 1984 Campaign Rhetoric of Representative George Hansen: A Pentadic Analysis.

    ERIC Educational Resources Information Center

    Kelley, Colleen E.

    1987-01-01

    Employs Kenneth Burke's pentad to examine rhetorical choices made by former U.S. Congressman George Hansen as he dramatized two situations: his felony conviction and his subsequent reelection bid. Suggests that Hansen's rhetoric was largely effective because it resulted in substantial identification with the voters of Idaho's Second Congressional…

  14. An Assessment of the Career Development Needs of ABE Students in Prince George's County, Maryland.

    ERIC Educational Resources Information Center

    Welsh-Hill, Janet

    A dual workshop/questionnaire approach was used in a needs assessment of adult basic education (ABE) students conducted in Prince George's County, Maryland, in spring 1980. The workshop advanced and clarified the concept of career development to teaching and administrative staff. Participants completed a needs assessment questionnaire according to…

  15. Ernst Mach, George Sarton and the Empiry of Teaching Science Part I

    ERIC Educational Resources Information Center

    Siemsen, Hayo

    2012-01-01

    George Sarton had a strong influence on modern history of science. The method he pursued throughout his life was the method he had discovered in Ernst Mach's "Mechanics" when he was a student in Ghent. Sarton was in fact throughout his life implementing a research program inspired by the epistemology of Mach. Sarton in turn inspired many others…

  16. George Washington: Soldier-Statesmen of the Constitution. A Bicentennial Series, No. 1.

    ERIC Educational Resources Information Center

    Army Center of Military History, Washington, DC.

    Possessed of an extraordinary strength of character and a wealth of public virtues, George Washington exhibited integrity, self-discipline, and a devotion to duty that made him the natural leader in the task of nation building. This booklet on Washington is one in a series on Revolutionary War soldiers who later signed the U.S. Constitution. The…

  17. Construction of a Creative and Self-Transcending Life: George Sudarshan's Conception and Experience of Creativity

    ERIC Educational Resources Information Center

    Raina, Maharaj

    2013-01-01

    This article presents a philosophical perspective on creativity as described in the writings of George Sudarshan, a highly accomplished theoretical physicist and natural philosopher whose vision of creativity was influenced by "the direct experience of transcendence." The article reviews his conceptualization of the various mental states…

  18. What Color Is Your Dog? Taking a Cue from Artist George Rodrigue

    ERIC Educational Resources Information Center

    Compton, June

    2009-01-01

    In this article, the author describes a lesson he created for his second-grade classes which was inspired by the children's book, "Why is Blue Dog Blue?", by George Rodrigue. In this lesson, the students make associations between places, food and events to determine the color of their dogs. (Contains 3 resources.)

  19. A Study of Selected Administrative Problems of George Peabody College for Teachers, 1937-1945.

    ERIC Educational Resources Information Center

    Petry, John Richard

    Problems concerning finance, faculty, and educational programs faced by George Peabody College for Teachers during 1937-1945 are examined, along with the solutions. Attention is directed to: circumstances surrounding problem identification, the background of each problem, who had responsibility for formulating each solution, other…

  20. George Kelly: The Theory of Personal Constructs and His Contributions to Personality Theory.

    ERIC Educational Resources Information Center

    Cote, Raymond L.

    Wheras many of the grand theories of psychology focus on factors such as the unconscious, power, perfection, or order, George Kelly proposed that humans are driven by the need for personal control and that this personal control comes as a result of being able to construct and predict the events of daily life on a continuous basis. His major two…