Science.gov

Sample records for activity based startup

  1. Activity Based Startup Plan for Prototype Vertical Denitration Calciner

    SciTech Connect

    SUTTER, C.S.

    1999-08-31

    Testing activities on the Prototype Vertical Denitration Calciner at PFP were suspended in January 1997 due to the hold on fissile material handling in the facility. The restart of testing activities will require a review through an activity based startup process based upon Integrated Safety Management (ISM) principles to verify readiness. The Activity Based Startup Plan has been developed for this process.

  2. Memristor based startup circuit for self biased circuits

    NASA Astrophysics Data System (ADS)

    Das, Mangal; Singh, Amit Kumar; Rathi, Amit; Singhal, Sonal

    2016-04-01

    This paper presents the design of a Memristor based startup circuit for self biased circuits. Memristor has many advantages over conventional CMOS devices such as low leakage current at nanometer scale, easy to manufacture. In this work the switching characteristics of memristor is utilized. First the theoretical equations describing the switching behavior of memristor are investigated. To prove the switching capability of Memristor, a startup circuit based on memristor is proposed which uses series combination of Memristor and capacitor. Proposed circuit is compared with the previously reported MOSFET based startup circuits. Comparison of different circuits was done to validate the results. Simulation results show that memristor based circuit can attain on (I = 12.94 µA) to off state (I = 1 .2 µA) in 25 ns while the MOSFET based startup circuits take on (I = 14.19 µA) to off state (I = 1.4 µA) in more than 90 ns. The benefit comes in terms of area because the number of components used in the circuit are lesser than the conventional startup circuits.

  3. Neural Network Based System for Equipment Startup Surveillance

    1996-12-18

    NEBSESS is a system for equipment surveillance and fault detection which relies on a neural-network based means for diagnosing disturbances during startup and for automatically actuating the Sequential Probability Ratio Test (SPRT) as a signal validation means during steady-state operation.

  4. Control of power sourced from a microbial fuel cell reduces its start-up time and increases bioelectrochemical activity.

    PubMed

    Boghani, Hitesh C; Kim, Jung Rae; Dinsdale, Richard M; Guwy, Alan J; Premier, Giuliano C

    2013-07-01

    Microbial fuel cell (MFC) performance depends on the selective development of an electrogenic biofilm at an electrode. Controlled biofilm enrichment may reduce start-up time and improve subsequent power performance. The anode potential is known to affect start-up and subsequent performance in electrogenic bio-catalytic consortia. Control strategies varying electrical load through gradient based maximum power point tracking (MPPT) and transient poised anode potential followed by MPPT are compared to static ohmic loading. Three replicate H-type MFCs were used to investigate start-up strategies: (1) application of an MPPT algorithm preceded by poised-potential at the anode (+0.645 V vs Ag/AgCl); (2) MFC connected to MPPT-only; (3) static external load of 1 kΩ and 500 Ω. Active control showed a significant reduction in start-up time from 42 to 22 days, along with 3.5-fold increase in biocatalytic activity after start-up. Such active control may improve applicability by accelerating start-up and enhancing MFC power and bio-catalytic performance. PMID:23708786

  5. Startup of distillation columns using profile position control based on nonlinear wave model

    SciTech Connect

    Han, M.; Park, S. |

    1999-04-01

    Startup of distillation columns is a very challenging control problem because of its strong nonlinearity and a wide operating range during the transient period. A nonlinear wave model captures the essential dynamic behavior of the distillation process so that it is possible to deal with the difficulties encountered during startup operation. This paper is concerned with the startup of distillation systems using nonlinear wave model based control developed by Han and Park. This control scheme uses profile positions as controlled variables and is based on the nonlinear wave model by Hwang and generic model control scheme by Lee and Sullivan. It can be applied to a binary or a multicomponent distillation system that can be represented as a pseudobinary. The proposed control scheme is shown by simulation studies to provide a safe and economic startup operation not only for dual composition control of a simple distillation column but also for a complex distillation configuration.

  6. Success and Failure in University-Based Startups

    NASA Astrophysics Data System (ADS)

    Dehn, J.; Webley, P.; Cunningham, K. W.

    2014-12-01

    Adapting from a traditional government-funded research program to supporting the work through a start-up company is a difficult (and often not successful) transition. This is made more challenging in that with the relative decline in federal funding for the sciences the transition is forced on many researchers as a matter of survival. The business model of traditional research is not that different from that of the private sector; the development of an idea, models or mock-ups of the product, pitching to sources of funding, creating and marketing the product. However they differ significantly in the environment in which they are applied, as well as in the life span of a project or product. The environments for pitching an idea and gaining investment are very different in academia from that of the private sector, and most academics are stymied by the new approach. In addition, many universities labor under the illusion that start-ups will be a windfall, when in reality they represent a long term investment that will not pay out for many years. This extended timeline is also something new to academics, though persistence pays and a project may take years to fund, after it is complete and the publications written, many in the geosciences go on to new ideas. If a business is to be successful it must continue with a product long term, and develop new ideas around it. A hopefully successful balance of these approaches is being tried at the University of Alaska Fairbanks, where start-ups can build upon university intellectual property and use university resources to build a successful business. In turn the business supports research and development, primarily through faculty, staff and students at the university.

  7. HHT-based crack identification method for start-up rotor

    NASA Astrophysics Data System (ADS)

    Li, Bing; Zhang, Chunlin; He, Zhengjia

    2012-09-01

    This paper presents a crack identification method for start-up rotor based on the Hilbert-Huang transform (HHT). With this method, the instantaneous frequency (IF) of each intrinsic mode function is obtained through the Hilbert transform, and the spectrum of IF is calculated accordingly. The influence of acceleration and crack depth on the rotor is analyzed through experiments. HHT is employed to detect the shallower crack, and is then tested during the start-up process of the rotor. The results of the experiment show that HHT is a better tool for crack detection than fast Fourier transform.

  8. [Study on the start-up of anaerobic ammonium oxidation process in biological activated carbon reactor].

    PubMed

    Lai, Wei-Yi; Zhou, Wei-Li; He, Sheng-Bing

    2013-08-01

    In order to shorten the start-up time of anaerobic ammonium oxidation (ANAMMOX) reactor, biological activated cabon reactor was applied. Three lab scale UASB reactors were seeded with anaerobic sludge, fed with synthetic wastewater containing ammonia and nitrite, and supplemented with granular activated carbon on day 0, 33 and 56, respectively. The nitrogen removal performance of the first reactor, into which GAC was added on day 0, showed no significant improvement in 90 days. After being suspended for about one month, the secondary start-up of this reactor succeeded in another 33 days (totally 123 days). 49 d and 85 d were taken for the other two reactors started up by the addition of GAC on day 33 and 56, respectively. After the reactors were started up, the average removal rates of total nitrogen were 89.8%, 86.7% and 86.7%, respectively. The start-up process could be divided into four stages, namely, the bacterial autolysis phase, the lag phase, the improve phase and the stationary phase, and the best time for adding GAC carrier was right after the start of the lag phase.

  9. Anammox-based technologies for nitrogen removal: Advances in process start-up and remaining issues.

    PubMed

    Ali, Muhammad; Okabe, Satoshi

    2015-12-01

    Nitrogen removal from wastewater via anaerobic ammonium oxidation (anammox)-based process has been recognized as efficient, cost-effective and low energy alternative to the conventional nitrification and denitrification processes. To date, more than one hundred full-scale anammox plants have been installed and operated for treatment of NH4(+)-rich wastewater streams around the world, and the number is increasing rapidly. Since the discovery of anammox process, extensive researches have been done to develop various anammox-based technologies. However, there are still some challenges in practical application of anammox-based treatment process at full-scale, e.g., longer start-up period, limited application to mainstream municipal wastewater and poor effluent water quality. This paper aimed to summarize recent status of application of anammox process and researches on technological development for solving these remaining problems. In addition, an integrated system of anammox-based process and microbial fuel cell is proposed for sustainable and energy-positive wastewater treatment.

  10. Three nonlinear performance relationships in the start-up state of IPMC strips based on finite element analysis

    NASA Astrophysics Data System (ADS)

    Peng, Han Min; Ding, Qing Jun; Hui, Yao; Li, Hua Feng; Zhao, Chun Sheng

    2010-03-01

    Ionic polymer-metal composites (IPMC) are a class of electroactive polymers (EAP), and they currently attract numerous researchers to study their performance characteristics and applications. However, research on its start-up characteristics still requires more attention. In the IPMC start-up state (the moment of applying an actuation voltage at the very beginning), its mechanical performance is different in the stable working state (working for at least 10 min). Therefore, this paper focuses on three performance relationships of an IPMC strip between its maximal tip deformation and voltage, its maximal stress and voltage, as well as its maximal strain and voltage, both in the two states. Different from other reports, we found that they present nonlinear tendencies in the start-up state rather than linear ones. Therefore, based on the equivalent bimorph beam model, a finite element electromechanical coupling calculation module in the ANSYS software was utilized to simulate these characteristics. Furthermore, a test system is introduced to validate the phenomena. As a whole, these three relationships and the FEA method may be beneficial for providing control strategies effectively to IPMC actuators, especially in their start-up states.

  11. Life Science Start-up Activities at the Universities of Applied Sciences (UAS).

    PubMed

    Huber, Gerda

    2014-12-01

    The universities of applied sciences (UAS) provide several values for the society and economy of a country. Besides education of high level professionals, transfer of knowledge from research to applications in industry or as new start-up companies is an important task. This is done in different ways in the various disciplines. In Life Sciences, a key industry branch in Switzerland, innovation is a competitive success factor and research findings from UAS/Life Sciences contribute to the valorization of new technologies to products, services and to business performance. In order to foster awareness for the innovation need of industry, UAS install processes and support for transfer of research and technology results to marketable applications. Furthermore they may facilitate contacts of researchers and students with entrepreneurs in order to animate start-up founding as a true alternative to being employed. Access to coaching and entrepreneurial training completes the essential basis. PMID:26508606

  12. Assessment study of RELAP5/MOD2, CYCLE 36. 04 based on spray start-up test for DOEL-4

    SciTech Connect

    Moeyaert, P.; Stubbe, E.

    1989-07-01

    This report presents an assessment study for the code RELAP-5 MOD-2 based on a pressurizer spray start-up test of the Doel-4 power plant. Doel-4 is a three loop WESTINGHOUSE PWR plant ordered by the EBES utility with a nominal power rating of 1000 MWe and equipped with preheater type E steam generators. A large series of commissioning tests are normally performed on new plants, of which the so called pressurizer spray and heater test (SU-PR-01) was performed on February 2nd 1985. TRACTEBEL, being the Architect-Engineer for this plant was closely involved with all start-up tests and was responsible for the final approval of the tests.

  13. Start-Up Characteristics of a Granule-Based Anammox UASB Reactor Seeded with Anaerobic Granular Sludge

    PubMed Central

    Wang, Yun-Yan; Tang, Chong-Jian; Chai, Li-Yuan; Xu, Kang-Que; Song, Yu-Xia

    2013-01-01

    The granulation of anammox sludge plays an important role in the high nitrogen removal performance of the anammox reactor. In this study, anaerobic granular sludge was selected as the seeding sludge to start up anammox reactor in order to directly obtain anammox granules. Results showed that the anammox UASB reactor was successfully started up by inoculating anaerobic granular sludge, with substrate capacity of 4435.2 mg/(L·d) and average ammonium and nitrite removal efficiency of 90.36% and 93.29%, respectively. During the start-up course, the granular sludge initially disintegrated and then reaggregated and turned red, suggesting the high anammox performance. Zn-Fe precipitation was observed on the surface of granules during the operation by SEM-EDS, which would impose inhibition to the anammox activity of the granules. Accordingly, it is suggested to relatively reduce the trace metals concentrations, of Fe and Zn in the conventional medium. The findings of this study are expected to be used for a shorter start-up and more stable operation of anammox system. PMID:24455691

  14. Electrical start-up for diesel fuel processing in a fuel-cell-based auxiliary power unit

    NASA Astrophysics Data System (ADS)

    Samsun, Remzi Can; Krupp, Carsten; Tschauder, Andreas; Peters, Ralf; Stolten, Detlef

    2016-01-01

    As auxiliary power units in trucks and aircraft, fuel cell systems with a diesel and kerosene reforming capacity offer the dual benefit of reduced emissions and fuel consumption. In order to be commercially viable, these systems require a quick start-up time with low energy input. In pursuit of this end, this paper reports an electrical start-up strategy for diesel fuel processing. A transient computational fluid dynamics model is developed to optimize the start-up procedure of the fuel processor in the 28 kWth power class. The temperature trend observed in the experiments is reproducible to a high degree of accuracy using a dual-cell approach in ANSYS Fluent. Starting from a basic strategy, different options are considered for accelerating system start-up. The start-up time is reduced from 22 min in the basic case to 9.5 min, at an energy consumption of 0.4 kW h. Furthermore, an electrical wire is installed in the reformer to test the steam generation during start-up. The experimental results reveal that the generation of steam at 450 °C is possible within seconds after water addition to the reformer. As a result, the fuel processor can be started in autothermal reformer mode using the electrical concept developed in this work.

  15. Rapid start-up of the anammox process: Effects of five different sludge extracellular polymeric substances on the activity of anammox bacteria.

    PubMed

    Guo, Jianbo; Wang, Sihui; Lian, Jing; Ngo, Huu Hao; Guo, Wenshan; Liu, Yunman; Song, Yuanyuan

    2016-11-01

    This study investigated the rapid start-up of the anaerobic ammonium oxidation (anammox) strategy by inoculating different biomass ratios of denitrifying granular sludge and anammox bacteria. The results demonstrated that two reactors (R1 and R2) were rapidly and successfully started-up on days 25 and 28, respectively, with nitrogen removal rates (NRRs) of 0.70kg/(m(3)·d) and 0.72kg/(m(3)·d) at biomass ratios of 10:1 (R1) and 50:1 (R2). The explanation for rapid start-up was found by examining the effect of five different sludge extracellular polymeric substances (EPS) on the activity of anammox bacteria in the batch experiments. Batch experiments results first demonstrated that the denitrification sludge EPS (DS-EPS) enhanced the anammox bacteria activity the most, and NO2(-)-N, NH4(+)-N removal rates were 1.88- and 1.53-fold higher than the control with optimal DS-EPS volume of 10mL. The rapid start-up strategy makes possible the application of anammox to practical engineering. PMID:27612401

  16. Environmental performance of an integrated fixed-film activated sludge (IFAS) reactor treating actual municipal wastewater during start-up phase.

    PubMed

    Singh, Nitin Kumar; Kazmi, Absar Ahmad; Starkl, Markus

    2015-01-01

    The present study summarizes the start-up performance and lessons learned during the start-up and optimization of a pilot-scale plant employing integrated fixed film activated sludge (IFAS) process treating actual municipal wastewater. A comprehensive start-up was tailored and implemented to cater for all the challenges and problems associated with start-up. After attaining desired suspended biomass (2,000-3,000 mg/L) and sludge age (∼7 days), the average biological oxygen demand (BOD) and chemical oxygen demand (COD) removals were observed as 77.3 and 70.9%, respectively, at optimized conditions, i.e. hydraulic retention time (HRT), 6.9 h; return sludge rate, 160%. The influent concentrations of COD, BOD, total suspended solids, NH3-N, total nitrogen and total phosphorus were found to be in the range of 157-476 mg/L, 115-283 mg/L, 152-428 mg/L, 23.2-49.3 mg/L, 30.1-52 mg/L and 3.6-7.8 mg/L, respectively, and the minimum effluent concentrations were achieved as ∼49 mg/L, 23 mg/L, 35 mg/L, 2.2 mg/L, 3.4 mg/L and 2.8 mg/L, respectively, at optimum state. The present system was found effective in the removal of pathogenic bacteria (Escherichia coli, 79%; Salmonella spp., 97.5%; Shigella spp., 92.9%) as well as coliforms (total coliforms, 97.65%; faecal coliforms, 80.35%) without any disinfection unit. Moreover it was observed that the time required for the stabilization of the plant was approximately 3 weeks if other parameters (sludge age, HRT and dissolved oxygen) are set to optimized values. PMID:26540547

  17. Designing a Battery-Less Piezoelectric based Energy Harvesting Interface Circuit with 300 mV Startup Voltage

    NASA Astrophysics Data System (ADS)

    Sarker, M. R.; Ali, Sawal H. Md; Othman, M.; Islam, Shabiul

    2013-04-01

    This paper presents a designing a battery-less piezoelectric based energy harvesting interface circuits with 300mV step-up voltage. A technique (i.e., DC-DC Step-Up converter) has chosen for designing the startup voltage with low voltage energy (i.e., 300mV). The proposed method consumes very little power, and is especially suitable for the ambient environmental source, where energy harvested power is very low. The energy harvesting interface circuit consists of MOSFET bridge ac-dc rectifier, voltage regulator, dc-dc step-up converter and an energy storage device with capacitor at the output terminal, replacing this by external battery. This paper will study results these important issues regarding the efficiencies of the energy harvesting power conversion interface circuits considering the storage device low voltage. The achievement of our development circuit is able to boost up minimum 1.67 V for input DC voltage of 300mV. The overall circuit efficiency is greater than 80% following the simulation results. This research has focused on the application of Wireless Sensor Network (WSN) and bio-medical device can be operated without battery.

  18. Physics of Tokamak Plasma Start-up

    NASA Astrophysics Data System (ADS)

    Mueller, Dennis

    2012-10-01

    This tutorial describes and reviews the state-of-art in tokamak plasma start-up and its importance to next step devices such as ITER, a Fusion Nuclear Science Facility and a Tokamak/ST demo. Tokamak plasma start-up includes breakdown of the initial gas, ramp-up of the plasma current to its final value and the control of plasma parameters during those phases. Tokamaks rely on an inductive component, typically a central solenoid, which has enabled attainment of high performance levels that has enabled the construction of the ITER device. Optimizing the inductive start-up phase continues to be an area of active research, especially in regards to achieving ITER scenarios. A new generation of superconducting tokamaks, EAST and KSTAR, experiments on DIII-D and operation with JET's ITER-like wall are contributing towards this effort. Inductive start-up relies on transformer action to generate a toroidal loop voltage and successful start-up is determined by gas breakdown, avalanche physics and plasma-wall interaction. The goal of achieving steady-sate tokamak operation has motivated interest in other methods for start-up that do not rely on the central solenoid. These include Coaxial Helicity Injection, outer poloidal field coil start-up, and point source helicity injection, which have achieved 200, 150 and 100 kA respectively of toroidal current on closed flux surfaces. Other methods including merging reconnection startup and Electron Bernstein Wave (EBW) plasma start-up are being studied on various devices. EBW start-up generates a directed electron channel due to wave particle interaction physics while the other methods mentioned rely on magnetic helicity injection and magnetic reconnection which are being modeled and understood using NIMROD code simulations.

  19. Loop Heat Pipe Startup Behaviors

    NASA Technical Reports Server (NTRS)

    Ku, Jentung

    2016-01-01

    A loop heat pipe must start successfully before it can commence its service. The startup transient represents one of the most complex phenomena in the loop heat pipe operation. This paper discusses various aspects of loop heat pipe startup behaviors. Topics include the four startup scenarios, the initial fluid distribution between the evaporator and reservoir that determines the startup scenario, factors that affect the fluid distribution between the evaporator and reservoir, difficulties encountered during the low power startup, and methods to enhance the startup success. Also addressed are the pressure spike and pressure surge during the startup transient, and repeated cycles of loop startup and shutdown under certain conditions.

  20. Solenoid-free plasma start-up in spherical tokamaks

    NASA Astrophysics Data System (ADS)

    Raman, R.; Shevchenko, V. F.

    2014-10-01

    The central solenoid is an intrinsic part of all present-day tokamaks and most spherical tokamaks. The spherical torus (ST) confinement concept is projected to operate at high toroidal beta and at a high fraction of the non-inductive bootstrap current as required for an efficient reactor system. The use of a conventional solenoid in a ST-based fusion nuclear facility is generally believed to not be a possibility. Solenoid-free plasma start-up is therefore an area of extensive worldwide research activity. Solenoid-free plasma start-up is also relevant to steady-state tokamak operation, as the central transformer coil of a conventional aspect ratio tokamak reactor would be located in a high radiation environment but would be needed only during the initial discharge initiation and current ramp-up phases. Solenoid-free operation also provides greater flexibility in the selection of the aspect ratio and simplifies the reactor design. Plasma start-up methods based on induction from external poloidal field coils, helicity injection and radio frequency current drive have all made substantial progress towards meeting this important need for the ST. Some of these systems will now undergo the final stages of test in a new generation of large STs, which are scheduled to begin operations during the next two years. This paper reviews research to date on methods for inducing the initial start-up current in STs without reliance on the conventional central solenoid.

  1. Closed-form analytical solutions of high-temperature heat pipe startup and frozen startup limitation

    NASA Technical Reports Server (NTRS)

    Cao, Y.; Faghri, A.

    1992-01-01

    Previous numerical and experimental studies indicate that the high-temperature heat pipe startup process is characterized by a moving hot zone with relatively sharp fronts. Based on the above observation, a flat-front model for an approximate analytical solution is proposed. A closed-form solution related to the temperature distribution in the hot zone and the hot zone length as a function of time are obtained. The analytical results agree well with the corresponding experimental data, and provide a quick prediction method for the heat pipe startup performance. Finally, a heat pipe limitation related to the frozen startup process is identified, and an explicit criterion for the high-temperature heat pipe startup is derived. The frozen startup limit identified in this paper provides a fundamental guidance for high-temperature heat pipe design.

  2. Loop Heat Pipe Startup Behaviors

    NASA Technical Reports Server (NTRS)

    Ku, Jentung

    2014-01-01

    A loop heat pipe must start successfully before it can commence its service. The start-up transient represents one of the most complex phenomena in the loop heat pipe operation. This paper discusses various aspects of loop heat pipe start-up behaviors. Topics include the four start-up scenarios, the initial fluid distribution between the evaporator and reservoir that determines the start-up scenario, factors that affect the fluid distribution between the evaporator and reservoir, difficulties encountered during the low power start-up, and methods to enhance the start-up success. Also addressed are the thermodynamic constraint between the evaporator and reservoir in the loop heat pipe operation, the superheat requirement for nucleate boiling, pressure spike and pressure surge during the start-up transient, and repeated cycles of loop start-up andshutdown under certain conditions.

  3. The Role of Startups

    ScienceCinema

    Babinec, Sue

    2016-07-12

    Many ARPA-E-funded universities and research institutions have created start-up companies to further catalyze their next-generation technologies. Ambri and BlackPak are two examples of ARPA-E projects that were spun out by other institutions—Massachusetts Institute of Technology and SRI International, respectively—in an effort to get their technologies out of the lab and into the market quickly. This video features remarks from ARPA-E Senior Commercialization Advisor Sue Babinec and interviews with technologists at Ambri and BlackPak, who each tell the story of how their new companies spun out of the lab and have become agile startups capable of delivering real products to the marketplace.

  4. The Role of Startups

    SciTech Connect

    Babinec, Sue

    2015-02-11

    Many ARPA-E-funded universities and research institutions have created start-up companies to further catalyze their next-generation technologies. Ambri and BlackPak are two examples of ARPA-E projects that were spun out by other institutions—Massachusetts Institute of Technology and SRI International, respectively—in an effort to get their technologies out of the lab and into the market quickly. This video features remarks from ARPA-E Senior Commercialization Advisor Sue Babinec and interviews with technologists at Ambri and BlackPak, who each tell the story of how their new companies spun out of the lab and have become agile startups capable of delivering real products to the marketplace.

  5. Start-up of the completely autotrophic nitrogen removal process using low activity anammox inoculum to treat low strength UASB effluent.

    PubMed

    Malamis, S; Katsou, E; Frison, N; Di Fabio, S; Noutsopoulos, C; Fatone, F

    2013-11-01

    The start-up of the completely autotrophic nitrogen removal process was examined in a sequencing batch reactor (SBR) using low activity anoxic ammonium oxidation (anammox) inoculum. The SBR received effluent from an upflow anaerobic sludge blanket (UASB) that treated low strength wastewater. The volumetric nitrogen loading rate (vNLR) was first 0.24 ± 0.11 kg Nm(-3)d(-1) and then reduced to 0.10 ± 0.02 kg Nm(-3)d(-1). The average specific anammox activity was 2.27 ± 1.31 mg N (gVSS h)(-1), at 30°C representing an increase of 161% compared to the inoculum. The decrease in vNLR did not significantly affect anammox activity, but resulted in a decrease of denitrifying heterotrophic activity to very low levels after the first 30 days owing to the decrease of organic loading rate (OLR). Fluorescence in situ hybridization (FISH) analysis confirmed the stable presence of anammox bacteria in biomass. Numerous filamentous microorganisms were present, several of which were in a state of endogenous respiration. PMID:24077156

  6. Genetic Counselors in Startup Companies: Redefining the Genetic Counselor Role.

    PubMed

    Rabideau, Marina M; Wong, Kenny; Gordon, Erynn S; Ryan, Lauren

    2016-08-01

    Genetic counselors (GCs) have recently begun moving into non-clinic based roles in increasing numbers. A relatively new role for GCs is working for startup companies. Startups are newly established companies in the phase of developing and researching new scalable businesses. This article explores the experiences of four GCs working at different startup companies and aims to provide resources for GCs interested in learning more about these types of roles. The article describes startup culture, including a relatively flat organizational structure, quick product iterations, and flexibility, among other unique cultural characteristics. Financial considerations are described, including how to understand and evaluate a company's financial status, along with a brief explanation of alternate forms of compensation including stock options and equity. Specifically, the article details the uncertainties and rewards of working in a fast-paced startup environment that affords opportunities to try new roles and use the genetic counseling skill set in new ways. This article aims to aid GCs in determining whether a startup environment would be a good fit, learning how to evaluate a specific startup, and understanding how to market themselves for positions at startups.

  7. Genetic Counselors in Startup Companies: Redefining the Genetic Counselor Role.

    PubMed

    Rabideau, Marina M; Wong, Kenny; Gordon, Erynn S; Ryan, Lauren

    2016-08-01

    Genetic counselors (GCs) have recently begun moving into non-clinic based roles in increasing numbers. A relatively new role for GCs is working for startup companies. Startups are newly established companies in the phase of developing and researching new scalable businesses. This article explores the experiences of four GCs working at different startup companies and aims to provide resources for GCs interested in learning more about these types of roles. The article describes startup culture, including a relatively flat organizational structure, quick product iterations, and flexibility, among other unique cultural characteristics. Financial considerations are described, including how to understand and evaluate a company's financial status, along with a brief explanation of alternate forms of compensation including stock options and equity. Specifically, the article details the uncertainties and rewards of working in a fast-paced startup environment that affords opportunities to try new roles and use the genetic counseling skill set in new ways. This article aims to aid GCs in determining whether a startup environment would be a good fit, learning how to evaluate a specific startup, and understanding how to market themselves for positions at startups. PMID:26801784

  8. Energy losses on tokamak startup

    SciTech Connect

    Murray, J.G.; Rothe, K.E.; Bronner, G.

    1983-01-01

    During the startup of a tokamak reactor using poloidal field (PF) coils to induce plasma currents, the conducting structures carry induced currents. The associated energy losses in the circuits must be provided by the startup coils and the PF system. This paper provides quantitative and comparitive values for the energies required as a function of the thickness or resistivity of the torus shells.

  9. Challenges for Success in Startups

    NASA Astrophysics Data System (ADS)

    Spitzer, Richard

    2000-03-01

    The basic challenges to a startup company such as IME have stemmed from the need to balance the business world's goal of fast entry into the market place with the necessity for a solid foundation in technology. Our technology base is broad - indeed it has the makings of a new industry - and the lure of quick commercial success in a specific application could easily make IME vulnerable to the R&D might of giant international companies. The essential challenges for success play out in business/technology decision tradeoffs: (i) preserving equity and viability while keeping R&D momentum and establishing intellectual property, (ii) attracting investors while maintaining focus on long-range goals, and (iii) developing a complete team while protecting capital resources. This balancing act keeps the company agile and resilient, qualities that large corporations could emulate with profit.

  10. Rightpollex: From Patent To Startup

    NASA Astrophysics Data System (ADS)

    Leba, Monica; Ionica, Andreea Cristina; Dobra, Remus

    2015-07-01

    RightPollex is an innovative product patented and developed by a multidisciplinary team from the University of Petrosani. The paper presents not only the idea and implementation possibilities of this patent, but also the current stage on the path towards the development of startups, an initiative of our university together with a private investor. The result of this initiative is JV Sensor Ventures that supports several startups.

  11. Having your cake and eating it too; effective engagement in start-ups from an academic seat

    NASA Astrophysics Data System (ADS)

    Mirkin, Chad

    2012-02-01

    In order for scientific advances to have a positive impact on society, they must be successfully transitioned from conceptually fundamental endeavors in academic research laboratories to valuable enabling technologies at start-up companies. Nanosphere, NanoInk, and AuraSense are three start-up companies that have been spun out of Northwestern based on research initiated in my laboratory. These companies are focused on commercializing nanotechnology-based applications in the life science and semiconductor industries and have turned discoveries from my lab into viable commercial products. For example, several of the systems developed at these start-ups are in the clinical trial phase, with one already approved by the FDA, and they are poised to have a positive world-wide impact. Herein, I discuss the challenges associated with identifying commercial value in academic research projects, securing intellectual property, forming a company as a legal entity, and locating sources of start-up funds. Further, I will discuss the rewards of venturing into such enterprises and the ways of ensuring a start-up company's long-term success, while juggling the numerous responsibilities of an academic seat. I argue that these two activities are done not in competition, but rather are integral for driving the type of high-level, synergistic scientific research that is being done today.

  12. Defense waste processing facility startup progress report

    SciTech Connect

    Iverson, D.C.; Elder, H.H.

    1992-01-01

    The Savannah River Site (SRS) has been operating a nuclear fuel cycle since the 1950's to produce nuclear materials in support of the national defense effort. About 83 million gallons of high level waste produced since operation began have been consolidated into 33 million gallons by evaporation at the waste tank farm. The Department of Energy has authorized the construction of the Defense Waste Processing Facility (DWPF) to immobilize the waste as a durable borosilicate glass contained in stainless steel canisters, prior to emplacement in a federal repository. The DWPF is now mechanically complete and undergoing commissioning and run-in activities. Cold startup testing using simulated non-radioactive feeds is scheduled to begin in November 1992 with radioactive operation scheduled to begin in May 1994. While technical issues have been identified which can potentially affect DWPF operation, they are not expected to negatively impact the start of non-radioactive startup testing.

  13. Defense waste processing facility startup progress report

    SciTech Connect

    Iverson, D.C.; Elder, H.H.

    1992-07-01

    The Savannah River Site (SRS) has been operating a nuclear fuel cycle since the 1950`s to produce nuclear materials in support of the national defense effort. About 83 million gallons of high level waste produced since operation began have been consolidated into 33 million gallons by evaporation at the waste tank farm. The Department of Energy has authorized the construction of the Defense Waste Processing Facility (DWPF) to immobilize the waste as a durable borosilicate glass contained in stainless steel canisters, prior to emplacement in a federal repository. The DWPF is now mechanically complete and undergoing commissioning and run-in activities. Cold startup testing using simulated non-radioactive feeds is scheduled to begin in November 1992 with radioactive operation scheduled to begin in May 1994. While technical issues have been identified which can potentially affect DWPF operation, they are not expected to negatively impact the start of non-radioactive startup testing.

  14. DART's (Dallas Area Rapid Transit) LNG Bus Fleet Start-Up Experience (Alternative Fuel Transit Buses Brochure)

    SciTech Connect

    Battelle

    2000-06-30

    This report, based on interviews and site visits conducted in October 1999, describes the start-up activities of the DART liquefied natural gas program, identifying problem areas, highlighting successes, and capturing the lessons learned in DART's ongoing efforts to remain at the forefront of the transit industry.

  15. The Start-Up, Evolution and Impact of a Research Group in a University Developing Its Knowledge Base

    ERIC Educational Resources Information Center

    Horta, Hugo; Martins, Rui

    2014-01-01

    This article focuses on the understudied role of research groups contributing to develop the knowledge base of developing universities in regions lagging behind in human, financial and scientific resources. We analyse the evolution of a research group that, in less than 10 years, achieved worldwide recognition in the field of microelectronics,…

  16. Influence of dissolved oxygen concentration on the start-up of the anammox-based process: ELAN®.

    PubMed

    Morales, N; Val del Río, A; Vázquez-Padín, J R; Gutiérrez, R; Fernández-González, R; Icaran, P; Rogalla, F; Campos, J L; Méndez, R; Mosquera-Corral, A

    2015-01-01

    The anammox-based process ELAN® was started-up in two different sequencing batch reactor (SBR) pilot plant reactors treating municipal anaerobic digester supernatant. The main difference in the operation of both reactors was the dissolved oxygen (DO) concentration in the bulk liquid. SBR-1 was started at a DO value of 0.4 mg O2/L whereas SBR-2 was started at DO values of 3.0 mg O2/L. Despite both reactors working at a nitrogen removal rate of around 0.6 g N/(L d), in SBR-1, granules represented only a small fraction of the total biomass and reached a diameter of 1.1 mm after 7 months of operation, while in SBR-2 the biomass was mainly composed of granules with an average diameter of 3.2 mm after the same operational period. Oxygen microelectrode profiling revealed that granules from SBR-2 where only fully penetrated by oxygen with DO concentrations of 8 mg O2/L while granules from SBR-1 were already oxygen penetrated at DO concentrations of 1 mg O2/L. In this way granules from SBR-2 performed better due to the thick layer of ammonia oxidizing bacteria, which accounted for up to 20% of all the microbial populations, which protected the anammox bacteria from non-suitable liquid media conditions. PMID:26247749

  17. University Start-ups: A Better Business Model

    NASA Astrophysics Data System (ADS)

    Dehn, J.; Webley, P. W.

    2015-12-01

    Many universities look to start-up companies as a way to attract faculty, supporting research and students as traditional federal sources become harder to come by. University affiliated start-up companies can apply for a broader suite of grants, as well as market their services to a broad customer base. Often university administrators see this as a potential panacea, but national statistics show this is not the case. Rarely do universities profit significantly from their start-ups. With a success rates of around 20%, most start-ups end up costing the university money as well as faculty-time. For the faculty, assuming they want to continue in academia, a start-up is often unattractive because it commonly leads out of academia. Running a successful business as well as maintaining a strong teaching and research load is almost impossible to do at the same time. Most business models and business professionals work outside of academia, and the models taught in business schools do not merge well in a university environment. To mitigate this a new business model is proposed where university start-ups are aligned with the academic and research missions of the university. A university start-up must work within the university, directly support research and students, and the work done maintaining the business be recognized as part of the faculty member's university obligations. This requires a complex conflict of interest management plan and for the companies to be non-profit in order to not jeopardize the university's status. This approach may not work well for all universities, but would be ideal for many to conserve resources and ensure a harmonious relationship with their start-ups and faculty.

  18. Successful IT Start-Ups' HRD Practices: Four Cases in South Korea

    ERIC Educational Resources Information Center

    Cho, Yonjoo; McLean, Gary N.

    2009-01-01

    Purpose: The purpose of this paper is to identify South Korea's successful IT start-ups' HRD practices to determine whether there are steps that must be taken to maintain their HRD expertise for continued growth. Design/methodology/approach: A case study approach employing four fast-growing IT start-up cases was undertaken based on semi-structured…

  19. Trends in the Crowdfunding of Educational Technology Startups

    ERIC Educational Resources Information Center

    Antonenko, Pavlo D.; Lee, Brenda R.; Kleinheksel, A. J.

    2014-01-01

    This article presents an analysis of active crowdfunding campaigns posted on ten crowdfunding platforms in May 2013 to provide a glimpse of the recent trends in the crowdfunding of educational technology startups. We describe the characteristics of the most successful crowdfunding campaigns in educational technology and identify the most popular…

  20. Child Care Center Start-Up Manual (2nd Edition).

    ERIC Educational Resources Information Center

    Broome County Child Development Council, Inc., Binghamton, NY.

    This manual is intended to be used as a guideline for establishing a high quality child care program. It is based on New York State regulations and on widely accepted practices that support early childhood development. Chapter 1 gives an overview of the start-up process and includes a checklist of major tasks. Chapter 2 discusses assessment…

  1. Cone penetrometer demonstration standard startup review checklist

    SciTech Connect

    KRIEG, S.A.

    1998-11-09

    Startup readiness for the Cone Penetrometer Demonstration in AX Tank Farm will be verified through the application of a Standard Startup Review Checklist. This is a listing of those items essential to demonstrating readiness to start the Cone Penetrometer Demonstration in AX Tank Farm.

  2. When Do Start-Ups Make Sense?

    ERIC Educational Resources Information Center

    Langemeyer, Clement J.

    2005-01-01

    The start-up has received considerable attention in the last few years. While the National Research Council of Canada has generated many start-ups over its 88-year history, the creation of a formal entrepreneurship programme in the mid-1990s dramatically accelerated the pace at which they were created. Many factors come into play in the decision…

  3. The physics of tokamak start-up

    SciTech Connect

    Mueller, D.

    2013-05-15

    Tokamak start-up on present-day devices usually relies on inductively induced voltage from a central solenoid. In some cases, inductive startup is assisted with auxiliary power from electron cyclotron radio frequency heating. International Thermonuclear Experimental Reactor, the National Spherical Torus Experiment Upgrade and JT60, now under construction, will make use of the understanding gained from present-day devices to ensure successful start-up. Design of a spherical tokamak (ST) with DT capability for nuclear component testing would require an alternative to a central solenoid because the small central column in an ST has insufficient space to provide shielding for the insulators in the solenoid. Alternative start-up techniques such as induction using outer poloidal field coils, electron Bernstein wave start-up, coaxial helicity injection, and point source helicity injection have been used with success, but require demonstration of scaling to higher plasma current.

  4. The Physics of Tokamak Start-up

    SciTech Connect

    D. Mueller

    2012-11-13

    Tokamak start-up on present-day devices usually relies on inductively induced voltage from a central solenoid. In some cases inductive startup is assisted with auxiliary power from electron cyclotron radio frequency heating. ITER, the National Spherical Torus eXperiment Upgrade and JT60, now under construction, will make use of the understanding gained from present-day devices to ensure successful start-up. Design of a spherical tokamak (ST) with DT capability for nuclear component testing would require an alternative to a central solenoid because the small central column in an ST has insufficient space to provide shielding for the insulators in the solenoid. Alternative start-up techniques such as induction using outer poloidal field coils, electron Bernstein wave start-up, coaxial helicity injection and point source helicity injection have been used with success, but require demonstration of scaling to higher plasma current.

  5. 75 FR 68989 - Approval and Promulgation of Implementation Plans; Texas; Excess Emissions During Startup...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION... Startup, Shutdown, Maintenance, and Malfunction Activities AGENCY: Environmental Protection Agency (EPA... Environmental Quality (TCEQ) in a letter dated January 23, 2006 (the January 23, 2006 SIP submittal)....

  6. Automated start-up of EBR-II: A preview

    SciTech Connect

    Kisner, R.A.

    1989-01-01

    Oak Ridge National Laboratory (ORNL) and Argonne National Laboratory (ANL) are undertaking a joint project to develop control philosophies, strategies, and algorithms for computer control of the start-up mode of the Experimental Breeder Reactor II (EBR-II). The major objective of this project is to show that advanced liquid-metal reactor (LMR) plants can be operated from low power to full power using computer control. Development of an automated control system with this objective in view will help resolve specific issues and provide proof through demonstration that automatic control for plant start-up is feasible. This paper describes the approach that will be used to develop such a system and some of the features it is expected to have. Structured, rule-based methods, which will provide start-up capability from a variety of initial plant conditions and degrees of equipment operability, will be used for accomplishing mode changes during plant start-up. Several innovative features will be incorporated such as signal, command, and strategy validation to maximize reliability, flexibility to accommodate a wide range of plant conditions, and overall utility. Continuous control design will utilize figures of merit to evaluate how well the controller meets the mission requirements. The operator interface will have unique ''look ahead'' features to let the operator see what will happen next. 15 refs., 7 figs., 1 tab.

  7. CGCC repowering nears commercial startup

    SciTech Connect

    Cook, J.J.; Lednicky, L.A.

    1995-06-01

    The Wabash River Project is a joint venture of Destec Energy Inc. (Destec) of Houston, Texas, and PSI. These companies formed a unique partnership to jointly develop, design, construct, own and operate a commercial coal gasification combined-cycle (CGCC) power plant at PSI`s Wabash River Generating Station. With this project, Destec and PSI are participating in the US Department of Energy`s (DOE) Clean Coal Technology (CCT) Program to demonstrate coal gasification repowering of an existing generating unit affected by the Clean Air Act Amendments (CAAA). This first fully integrated commercial CGCC repowering project in the US will repower one of PSI`s six Wabash River units. Upon startup in 1995, the project will be the largest operating single-train CGCC plant in the world and will use locally mined high-sulfur coal to produce some of the lowest-cost electricity on the PSI system.

  8. CFD configurations for hydraulic turbine startup

    NASA Astrophysics Data System (ADS)

    Nicolle, J.; Giroux, A. M.; Morissette, J. F.

    2014-03-01

    This paper presents various numerical setups for modelling Francis turbine startups involving moving meshes and variable runner speed in order to help define best practices. During the accelerating phase of the startup, the flow is self-similar between channels, thus making single sector configuration appropriate. Adding the draft tube improves the results by allowing pressure recovery midway during in the startup. At the speed no-load regime, a rotating stall phenomenon occurs and can only be capted with the full runner included in the simulation. Comparison with experimental data, such as runner speed and strain gauge measurements, generally shows good agreement.

  9. Entrepreneurial patent management in pharmaceutical startups.

    PubMed

    Holgersson, Marcus; Phan, Tai; Hedner, Thomas

    2016-07-01

    Startups fill an increasingly important role as innovators in the pharmaceutical industry, and patenting is typically central to their success. This article aims to explore patent management in pharmaceutical startups. The results show that startups need to deal with several challenges related to patenting and an 'entrepreneurial' approach to patent management is called for. Resource constraints, venture capital provision, exits and other conditions and events must be readily considered in the patent management process to build a successful pharmaceutical venture, something that could benefit the pharmaceutical industry as a whole. PMID:26948802

  10. >venture>: Support for Early Stage Start-ups and Potential Entrepreneurs.

    PubMed

    Kauz, Lukas

    2014-12-01

    >venture>, the leading Swiss-wide business plan competition, is an ideal partner for young start-ups and entrepreneurs. For the upcoming tenth anniversary edition the competition will receive an update. Building upon a successful base of the past nine editions and equipped with contemporary networking events and more know-how transferring seminars, >venture> will fit even better into the Swiss start-up ecosystem. PMID:26508611

  11. Aeroelastic Modeling of a Nozzle Startup Transient

    NASA Technical Reports Server (NTRS)

    Wang, Ten-See; Zhao, Xiang; Zhang, Sijun; Chen, Yen-Sen

    2014-01-01

    Lateral nozzle forces are known to cause severe structural damage to any new rocket engine in development during test. While three-dimensional, transient, turbulent, chemically reacting computational fluid dynamics methodology has been demonstrated to capture major side load physics with rigid nozzles, hot-fire tests often show nozzle structure deformation during major side load events, leading to structural damages if structural strengthening measures were not taken. The modeling picture is incomplete without the capability to address the two-way responses between the structure and fluid. The objective of this study is to develop a tightly coupled aeroelastic modeling algorithm by implementing the necessary structural dynamics component into an anchored computational fluid dynamics methodology. The computational fluid dynamics component is based on an unstructured-grid, pressure-based computational fluid dynamics formulation, while the computational structural dynamics component is developed under the framework of modal analysis. Transient aeroelastic nozzle startup analyses at sea level were performed, and the computed transient nozzle fluid-structure interaction physics presented,

  12. Mathematical modeling and analysis of heat pipe start-up from the frozen state

    SciTech Connect

    Jang, J.H.; Faghri, A.; Chang, W.S.; Mahefkey, E.T.

    1989-08-01

    The start-up process of a frozen heat pipe is described and a complete mathematical model for the start-up of the frozen heat pipe is developed based on the existing experimental data, which is simplified and solved numerically. The two-dimensional transient model for the wall and wick is coupled with the one-dimensional transient model for the vapor flow when vaporization and condensation occur at the interface. A parametric study is performed to examine the effect of the boundary specification at the surface of the outer wall on the successful start-up from the frozen state. For successful start-up, the boundary specification at the outer wall surface must melt the working substance in the condenser before dry-out takes place in the evaporator.

  13. Mathematical modeling and analysis of heat pipe start-up from the frozen state

    NASA Technical Reports Server (NTRS)

    Jang, Jong Hoon; Faghri, Amir; Chang, Won Soon; Mahefkey, Edward T.

    1989-01-01

    The start-up process of a frozen heat pipe is described and a complete mathematical model for the start-up of the frozen heat pipe is developed based on the existing experimental data, which is simplified and solved numerically. The two-dimensional transient model for the wall and wick is coupled with the one-dimensional transient model for the vapor flow when vaporization and condensation occur at the interface. A parametric study is performed to examine the effect of the boundary specification at the surface of the outer wall on the successful start-up from the frozen state. For successful start-up, the boundary specification at the outer wall surface must melt the working substance in the condenser before dry-out takes place in the evaporator.

  14. Mathematical modeling and analysis of heat pipe start-up from the frozen state

    NASA Technical Reports Server (NTRS)

    Jang, J. H.; Faghri, A.; Chang, W. S.; Mahefkey, E. T.

    1990-01-01

    The start-up process of a frozen heat pipe is described and a complete mathematical model for the start-up of the frozen heat pipe is developed based on the existing experimental data, which is simplified and solved numerically. The two-dimensional transient model for the wall and wick is coupled with the one-dimensional transient model for the vapor flow when vaporization and condensation occur at the interface. A parametric study is performed to examine the effect of the boundary specification at the surface of the outer wall on the successful start-up from the frozen state. For successful start-up, the boundary specification at the outer wall surface must melt the working substance in the condenser before dry-out takes place in the evaporator.

  15. Avoid problems during distillation column startups

    SciTech Connect

    Sloley, A.W.

    1996-07-01

    The startup of a distillation column is the end product of the design process. Indeed, startup is the culmination of the theory and practice of designing the column to meet the process objectives. The author will direct most of this discussion towards column revamps due to their inherent complexity; however, the points apply equally to new columns, as well. The most important question that must be answered prior to a startup is how will the distillation system changes affect initial startup, process control of the system, and normal day-to-day operations? How will the operators run the system? Steady-state distillation-column simulations alone cannot provide an authoritative answer and, indeed, engineers` over-reliance on software too often has led them to ignore many practical aspects. Computer modeling, while an important engineering tool, is not reality. Distillation columns are real functioning pieces of equipment that require practical skills to successfully modify. They are not steady-state solutions that result from converged computer simulations. Early planning, coupled with thorough inspections and comprehensive reviews of instrumentation and procedures, can play a key role in assuring smooth startups.

  16. Start-up and operating costs for artisan cheese companies.

    PubMed

    Bouma, Andrea; Durham, Catherine A; Meunier-Goddik, Lisbeth

    2014-01-01

    Lack of valid economic data for artisan cheese making is a serious impediment to developing a realistic business plan and obtaining financing. The objective of this study was to determine approximate start-up and operating costs for an artisan cheese company. In addition, values are provided for the required size of processing and aging facilities associated with specific production volumes. Following in-depth interviews with existing artisan cheese makers, an economic model was developed to predict costs based on input variables such as production volume, production frequency, cheese types, milk types and cost, labor expenses, and financing. Estimated values for start-up cost for processing and aging facility ranged from $267,248 to $623,874 for annual production volumes of 3,402 kg (7,500 lb) and 27,216 kg (60,000 lb), respectively. First-year production costs ranged from $65,245 to $620,094 for the above-mentioned production volumes. It is likely that high start-up and operating costs remain a significant entry barrier for artisan cheese entrepreneurs.

  17. Start-up and operating costs for artisan cheese companies.

    PubMed

    Bouma, Andrea; Durham, Catherine A; Meunier-Goddik, Lisbeth

    2014-01-01

    Lack of valid economic data for artisan cheese making is a serious impediment to developing a realistic business plan and obtaining financing. The objective of this study was to determine approximate start-up and operating costs for an artisan cheese company. In addition, values are provided for the required size of processing and aging facilities associated with specific production volumes. Following in-depth interviews with existing artisan cheese makers, an economic model was developed to predict costs based on input variables such as production volume, production frequency, cheese types, milk types and cost, labor expenses, and financing. Estimated values for start-up cost for processing and aging facility ranged from $267,248 to $623,874 for annual production volumes of 3,402 kg (7,500 lb) and 27,216 kg (60,000 lb), respectively. First-year production costs ranged from $65,245 to $620,094 for the above-mentioned production volumes. It is likely that high start-up and operating costs remain a significant entry barrier for artisan cheese entrepreneurs. PMID:24746129

  18. Thermophilic anaerobic digestion of source-sorted organic fraction of household municipal solid waste: start-up procedure for continuously stirred tank reactor.

    PubMed

    Angelidaki, Irini; Chen, Xingxing; Cui, Junbo; Kaparaju, Prasad; Ellegaard, Lars

    2006-08-01

    Two feeding strategies for start-up of continuously stirred tank reactors (CSTR) treating source-sorted organic fraction of household municipal solid waste (SS-OFMSW) at 55 degrees C were evaluated. Two reactors were started up separately with a limited amount of initial inoculum (i.e. 10% of the final volume of 3.5l) and operated in a fed batch mode until the reactors were filled (30 days). A reference reactor was filled up with 3.5l of inoculum and fed at a constant rate (11.4 g volatile solids (VS)/d). Loading at progressively increasing rate (from 1.7 to 15 gVS/d), as calculated based on an activated biomass concept, showed superior process performance compared to a fixed feed rate (5.7 gVS/d). Methane yield of 0.32 m(3)/kg VS was produced during the start-up in reactor filled at progressively increasing rate and was comparable to the reference reactor. On the contrary, significant inhibition due to volatile fatty acid (VFA) build-up, mainly due to butyrate, was noticed in the reactor filled at constant rate. Thus, low initial and progressive increasing inoculum loading rate could be used as a strategy for a successful start-up of CSTR treating SS-OFMSW as it allowed a gradual acclimation of the biomass. Lab-scale results were further reaffirmed from the start-up of a full-scale plant (7000 m(3) total capacity) which was supplied with inoculum corresponding to approx. 16% of final volume and operated in a fed batch mode until the reactors were filled (58 days). Stable biogas production with low VFA (<3 g/L; based on titration method) were noticed during the start-up period when fed at progressively increasing rate. Thus, a controlled and reliable start-up procedure was found essential, which could allow rapid process stabilization and time to focus on other technical aspects of plant operation. In addition, the influence of substrate to inoculum amount (1.5-30% TS) and temperature (5-65 degrees C) on anaerobic degradation and methane production of SS-OFMSW was

  19. Phase Startup Initiative Phases 3 and 4 Test Plan and Test Specification ( OCRWM)

    SciTech Connect

    PAJUNEN, A.L.; LANGEVIN, M.J.

    2000-08-07

    Construction for the Spent Nuclear Fuel (SNF) Project facilities is continuing per the Level III Baseline Schedule, and installation of the Fuel Retrieval System (FRS) and Integrated Water Treatment System (IWTS) in K West Basin is now complete. In order to accelerate the project, a phased start up strategy to initiate testing of the FRS and IWTS early in the overall project schedule was proposed (Williams 1999). Wilkinson (1999) expands the definition of the original proposal into four functional testing phases of the Phased Startup Initiative (PSI). Phases 1 and 2 are based on performing functional tests using dummy fuel. This test plan provides overall guidance for Phase 3 and 4 tests, which are performed using actual irradiated N fuel assemblies. The overall objective of the Phase 3 and 4 testing is to verify how the FRS and IWTS respond while processing actual fuel. Conducting these tests early in the project schedule will allow identification and resolution of equipment and process problems before they become activities on the start-up critical path. The specific objectives of this test plan are to: Define the Phase 3 and 4 test scope for the FRS and IWTS; Provide detailed test requirements that can be used to write the specific test procedures; Define data required and measurements to be taken. Where existing methods to obtain these do not exist, enough detail will be provided to define required additional equipment; and Define specific test objectives and acceptance criteria.

  20. 40 CFR 63.1111 - Startup, shutdown, and malfunction.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Occupational Safety and Health Administration (OSHA) or other plan, provided the alternative plans meet all the... Control Technology Standards § 63.1111 Startup, shutdown, and malfunction. (a) Startup, shutdown,...

  1. 40 CFR 63.1111 - Startup, shutdown, and malfunction.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Occupational Safety and Health Administration (OSHA) or other plan, provided the alternative plans meet all the... Control Technology Standards § 63.1111 Startup, shutdown, and malfunction. (a) Startup, shutdown,...

  2. Finding the Data: A Start-Up List of Outcome Measures with Annotations. A Companion Document to "The Case for Shifting to Results-Based Accountability."

    ERIC Educational Resources Information Center

    Brown, Brett; Weitz, Judith

    Shifting to results-based accountability is a difficult stage in reforming family and children's services. Heretofore, these services have been more concerned with the number of clients seen or papers processed than in their clients' quality of life. This document should help communities find the data they need to measure qualitative outcomes. It…

  3. Startup Hopefuls Test Their Ideas with Educators

    ERIC Educational Resources Information Center

    Tomassini, Jason

    2012-01-01

    "Educator day" is one of the most important and nerve-racking for the people taking part in Imagine K12, the biggest incubator program in the United States specifically for education technology startups. Many entrepreneurs in K-12 believe technology can solve education's problems, but don't work to understand those problems before prescribing…

  4. 20 CFR 632.254 - Program startup.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Program startup. 632.254 Section 632.254 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INDIAN AND NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.254 Program...

  5. 20 CFR 632.254 - Program startup.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Program startup. 632.254 Section 632.254 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INDIAN AND NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.254 Program...

  6. Light duty utility arm startup plan

    SciTech Connect

    Barnes, G.A.

    1998-09-01

    This plan details the methods and procedures necessary to ensure a safe transition in the operation of the Light Duty Utility Arm (LDUA) System. The steps identified here outline the work scope and identify responsibilities to complete startup, and turnover of the LDUA to Characterization Project Operations (CPO).

  7. Mixed Stream Test Rig (MISTER) Startup Report

    SciTech Connect

    Charles Park

    2011-02-01

    This report describes the work accomplished to date to design, procure, assemble, authorize, and startup the Mixed Stream Test Rig (MISTER) at the Idaho National Laboratory (INL). It describes the reasons for establishing this capability, physical configuration of the test equipment, operations methodology, initial success, and plans for completing the initial 1,000 hour test.

  8. 40 CFR 63.762 - Startups, shutdowns, and malfunctions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... apply at all times except during startups or shutdowns, during malfunctions, and during periods of non... which this subpart applies. However, during the startup, shutdown, malfunction, or period of non... provisions to which they are subject must do so during the startup, shutdown, malfunction, or period of...

  9. 40 CFR 63.762 - Startups, shutdowns, and malfunctions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... apply at all times except during startups or shutdowns, during malfunctions, and during periods of non... which this subpart applies. However, during the startup, shutdown, malfunction, or period of non... provisions to which they are subject must do so during the startup, shutdown, malfunction, or period of...

  10. 40 CFR 63.762 - Startups, shutdowns, and malfunctions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... apply at all times except during startups or shutdowns, during malfunctions, and during periods of non... which this subpart applies. However, during the startup, shutdown, malfunction, or period of non... provisions to which they are subject must do so during the startup, shutdown, malfunction, or period of...

  11. Fuel Cell Power Model Version 2: Startup Guide, System Designs, and Case Studies. Modeling Electricity, Heat, and Hydrogen Generation from Fuel Cell-Based Distributed Energy Systems

    SciTech Connect

    Steward, D.; Penev, M.; Saur, G.; Becker, W.; Zuboy, J.

    2013-06-01

    This guide helps users get started with the U.S. Department of Energy/National Renewable Energy Laboratory Fuel Cell Power (FCPower) Model Version 2, which is a Microsoft Excel workbook that analyzes the technical and economic aspects of high-temperature fuel cell-based distributed energy systems with the aim of providing consistent, transparent, comparable results. This type of energy system would provide onsite-generated heat and electricity to large end users such as hospitals and office complexes. The hydrogen produced could be used for fueling vehicles or stored for later conversion to electricity.

  12. Impact of reactor configuration on anammox process start-up: MBR versus SBR.

    PubMed

    Tao, Yu; Gao, Da-Wen; Fu, Yuan; Wu, Wei-Min; Ren, Nan-Qi

    2012-01-01

    Anaerobic ammonium oxidation (anammox) is an energy saving biological nitrogen removal process which was limited to slow growth rate of anammox bacteria during start-up period. This study investigated the start-up of anammox process by a laboratory sequential batch reactor (SBR) for 218 days and subsequently modified the reactor as a membrane bioreactor (MBR) for 178 days. Modification of a SBR as MBR with installation of an external membrane module resulted in acceleration of specific anammox activity by 19 times. The acceleration of specific anammox activity with MBR was further confirmed by starting-up another MBR for a 242 day period. Molecular microbial analyses showed that Candidatus "Brocadia anammoxidans" and Candidatus "Kuenenia stuttgartiensis" were the dominant species in the inocula and biomass developed in the reactor. The start-up with MBR appeared to be more effective than SBR for the enrichment of anammox bacteria due to high sludge retention property of MBR configuration. PMID:22104096

  13. Royal Society offers funds for technology start-ups

    NASA Astrophysics Data System (ADS)

    Clery, Daniel

    2008-04-01

    Scientists with a good idea ripe for commercial exploitation will no longer have to hawk their wares to bankers and private investors to get financial backing: the Royal Society is also about to get into the venture-capital business. The society is planning to set up an enterprise fund to buy equity in start-up companies based on outstanding technology - covering everything from renewable energy and carbon capture to water purification. "If there are difficulties getting science into the marketplace, the society has a role helping with that," says chemical physicist Andrew Mackintosh, a former chief executive of Oxford Instruments who has been brought in to manage the fund.

  14. Mathematical modelling of methanogenic reactor start-up: Importance of volatile fatty acids degrading population.

    PubMed

    Jabłoński, Sławomir J; Łukaszewicz, Marcin

    2014-12-01

    Development of balanced community of microorganisms is one of the obligatory for stable anaerobic digestion. Application of mathematical models might be helpful in development of reliable procedures during the process start-up period. Yet, the accuracy of forecast depends on the quality of input and parameters. In this study, the specific anaerobic activity (SAA) tests were applied in order to estimate microbial community structure. Obtained data was applied as input conditions for mathematical model of anaerobic digestion. The initial values of variables describing the amount of acetate and propionate utilizing microorganisms could be calculated on the basis of SAA results. The modelling based on those optimized variables could successfully reproduce the behavior of a real system during the continuous fermentation.

  15. Life Sciences Start-ups in Switzerland: CTI and its Support for Young Entrepreneurs.

    PubMed

    Sekanina, Klara

    2014-12-01

    According to the Global Entrepreneurship Monitor 2013, perceived opportunities to start a business in Switzerland are high and rank above average compared to other innovation-based countries. 2013 was a record year for start-ups in Switzerland. Around 40,000 new businesses were recorded in the commercial register and the trend is set to continue. There are two main criteria that lead to success, particularly for science- or technology- based start-ups: first of all, it is the business or product idea itself, and secondly it is the entrepreneurial team. CTI is supporting innovation in a manner that responds to a need in the market identified by industry.

  16. Achieving and Sustaining New Knowledge Development in High-Expectation Start-Ups

    ERIC Educational Resources Information Center

    Matricano, Diego

    2010-01-01

    In markets characterized by strong competition, new knowledge and new knowledge development are generally recognized as the key means for an enterprise to gain competitive advantage. This knowledge-based competitive advantage is critical for all commercial ventures, but is especially so for high-expectation start-ups (technology-based ventures…

  17. Start-up control system and vessel for LMFBR

    DOEpatents

    Durrant, Oliver W.; Kakarala, Chandrasekhara R.; Mandel, Sheldon W.

    1987-01-01

    A reflux condensing start-up system comprises a steam generator, a start-up vessel connected parallel to the steam generator, a main steam line connecting steam outlets of the steam generator and start-up vessel to a steam turbine, a condenser connected to an outlet of the turbine and a feedwater return line connected between the condenser and inlets of the steam generator and start-up vessel. The start-up vessel has one or more heaters at the bottom thereof for heating feedwater which is supplied over a start-up line to the start-up vessel. Steam is thus generated to pressurize the steam generator before the steam generator is supplied with a heat transfer medium, for example liquid sodium, in the case of a liquid metal fast breeder reactor. The start-up vessel includes upper and lower bulbs with a smaller diameter mid-section to act as water and steam reservoirs. The start-up vessel can thus be used not only in a start-up operation but as a mixing tank, a water storage tank and a level control at low loads for controlling feedwater flow.

  18. Start-up control system and vessel for LMFBR

    DOEpatents

    Durrant, Oliver W.; Kakarala, Chandrasekhara R.; Mandel, Sheldon W.

    1987-01-01

    A reflux condensing start-up system includes a steam generator, a start-up vessel connected parallel to the steam generator, a main steam line connecting steam outlets of the steam generator and start-up vessel to a steam turbine, a condenser connected to an outlet of the turbine and a feedwater return line connected between the condenser and inlets of the steam generator and start-up vessel. The start-up vessel has one or more heaters at the bottom thereof for heating feedwater which is supplied over a start-up line to the start-up vessel. Steam is thus generated to pressurize the steam generator before the steam generator is supplied with a heat transfer medium, for example liquid sodium, in the case of a liquid metal fast breeder reactor. The start-up vessel includes upper and lower bulbs with a smaller diameter mid-section to act as water and steam reservoirs. The start-up vessel can thus be used not only in a start-up operation but as a mixing tank, a water storage tank and a level control at low loads for controlling feedwater flow.

  19. Start-up performance of Anammox process in a fixed bed reactor (FBR) filled with honeycomb-like polypropylene carriers.

    PubMed

    Wang, Tao; Shen, Boxiong; Zhang, Sha; Wang, Zhiqiang; Tian, Li

    2016-01-01

    Novel honeycomb-like carriers, made of polypropylene, were applied to enhance biomass retention capacity so as to improve Anammox start-up performance in a fixed bed reactor (FBR). The reactor was operated for 3 months. On day 45, Anammox activity appeared. After 61 days' operation, the removal efficiencies of ammonium and nitrite were both over 91% based on 70 mg N L(-1) of the influent ammonium and influent nitrite, indicating that a remarkable Anammox activity was attained. A final specific Anammox activity of 0.12 g NH4(+)-N gVSS(-1) d(-1) was reached (VSS: volatile suspended solids). The FBR showed a good capacity for resisting shock loading and was more able to resist shock loading of nitrogen concentration than resist hydraulic shock loading. Phylogenetic analysis showed that Candidatus Brocadia anammoxidans' and Candidatus Kuenenia stuttgartiensis' were detected in the mature biofilm, and Candidatus Brocadia anammoxidans' was the dominant Anammox strain. Candidatus Kuenenia stuttgartiensis' played a positive role in the reactor performance, as it could consumed nitrite quickly and efficiently so as to avoid an adverse effect of temporary nitrite accumulation. The results showed that the honeycomb-like carriers were suitable for start-up of Anammox. PMID:27120639

  20. Emissions of polychlorinated diphenyl ethers from a municipal solid waste incinerator during the start-up operation.

    PubMed

    Yang, Jing-Sing; Lin, Sheng-Lun; Lin, Ta-Chang; Wu, Yee-Lin; Wang, Lin-Chi; Chang-Chien, Guo-Ping

    2015-12-15

    This study examines the emissions of polychlorinated diphenyl ethers (PCDEs) during the start-up processes of a municipal solid waste incinerator (MSWI). Both normal and modified emission control start-ups were tested. Fifteen samples were taken from the flue gas with increasing furnace temperature. Peak PCDE concentrations of 1.48-10.3 ng/Nm(3) were observed at 8-11 h after the start of combustion, when the furnace temperature was in the range of 267-440 °C, that also needed for PCDD/F formation by de novo synthesis. The PCDE emissions could thus, be reduced by current control techniques. Furthermore, the modified control strategies inhibited PCDE formation at the beginning of combustion, and led to an 86% reduction in the maximum PCDE concentration. The overall start-up emissions were calculated as 1.01-3.08 mg, while the annual PCDE emissions with one start-up operation were found to be 7.48-9.64 mg. However, total PCDE emissions will increase by 12-69% if the number of start-up runs increases to between two and eight times per year. Consequently, the prevention of the unnecessary start-ups and advanced activation of the related emission control system are both efficient ways to reduce PCDE emissions. PMID:26124066

  1. Reactor power system deployment and startup

    NASA Technical Reports Server (NTRS)

    Wetch, J. R.; Nelin, C. J.; Britt, E. J.; Klein, G.

    1985-01-01

    This paper addresses issues that should receive further examination in the near-term as concept selection for development of a U.S. space reactor power system is approached. The issues include: the economics, practicality and system reliability associated with transfer of nuclear spacecraft from low earth shuttle orbits to operational orbits, via chemical propulsion versus nuclear electric propulsion; possible astronaut supervised reactor and nuclear electric propulsion startup in low altitude Shuttle orbit; potential deployment methods for nuclear powered spacecraft from Shuttle; the general public safety of low altitude startup and nuclear safe and disposal orbits; the question of preferred reactor power level; and the question of frozen versus molten alkali metal coolant during launch and deployment. These issues must be considered now because they impact the SP-100 concept selection, power level selection, weight and size limits, use of deployable radiators, reliability requirements, and economics, as well as the degree of need for and the urgency of developing space reactor power systems.

  2. Noninductive RF startup in CDX-U

    NASA Astrophysics Data System (ADS)

    Jones, B.; Majeski, R.; Efthimion, P.; Kaita, R.; Menard, J.; Munsat, T.; Takase, Y.

    1998-11-01

    For the spherical torus (ST) to prove viable as a reactor, it will be necessary to devise techniques for noninductive plasma startup. Initial studies of noninductive plasma initiation have been performed on CDX-U, using the 100 kW high harmonic fast wave (HHFW) system in combination with the 1 kW 2.45 GHz electron cyclotron heating system used for breakdown. Modest density (ne ~ 10^12 cm-3), low temperature (5 eV) plasmas were formed, but the density profile was peaked far off-axis, very near the HHFW antenna. High neutral fill pressures were also required. In upcoming experiments, up to 500 kW of low frequency RF power will utilized for heating and noninductive current drive in the mode conversion regime in a target noninductive plasma formed by a combination of 5.6 and 14 GHz ECH (40 kW total). Modeling will be presented which indicates that startup to plasma currents of 60 kA is feasible with this system.

  3. Start-Up Costs in American Research Universities.

    ERIC Educational Resources Information Center

    Ehrenberg, Ronald G.; Rizzo, Michael J.; Condie, Scott S.

    This report briefly summarizes findings from the 2002 Cornell Higher Education Research Institute survey of start-up costs at the over 220 universities classified as research and doctoral universities by the Carnegie Foundation in 1994. It reports the mean start-up cost packages across institutions for new assistant professors and senior faculty,…

  4. Start-Up Training in Mississippi: Program Development Guide.

    ERIC Educational Resources Information Center

    Brooks, Kent; And Others

    Due to recent industrial growth in Mississippi and the shortage of trained manpower in numerous occupations, start-up training programs have originated to provide a pretrained work force for new or expanding industry in the State. Each start-up training program is a joint effort between a new or expanding industry and a public educational…

  5. 40 CFR 68.77 - Pre-startup review.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... owner or operator shall perform a pre-startup safety review for new stationary sources and for modified stationary sources when the modification is significant enough to require a change in the process safety information. (b) The pre-startup safety review shall confirm that prior to the introduction of...

  6. 30 CFR 57.14201 - Conveyor start-up warnings.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Conveyor start-up warnings. 57.14201 Section 57.14201 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Equipment Safety Practices and Operational Procedures § 57.14201 Conveyor start-up warnings. (a) When...

  7. 30 CFR 56.14201 - Conveyor start-up warnings.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Conveyor start-up warnings. 56.14201 Section 56.14201 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Equipment Safety Practices and Operational Procedures § 56.14201 Conveyor start-up warnings. (a) When...

  8. 30 CFR 56.14201 - Conveyor start-up warnings.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Conveyor start-up warnings. 56.14201 Section 56.14201 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Equipment Safety Practices and Operational Procedures § 56.14201 Conveyor start-up warnings. (a) When...

  9. 30 CFR 56.14201 - Conveyor start-up warnings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Conveyor start-up warnings. 56.14201 Section 56.14201 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Equipment Safety Practices and Operational Procedures § 56.14201 Conveyor start-up warnings. (a) When...

  10. 30 CFR 56.14201 - Conveyor start-up warnings.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Conveyor start-up warnings. 56.14201 Section 56.14201 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Equipment Safety Practices and Operational Procedures § 56.14201 Conveyor start-up warnings. (a) When...

  11. 30 CFR 57.14201 - Conveyor start-up warnings.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Conveyor start-up warnings. 57.14201 Section 57.14201 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Equipment Safety Practices and Operational Procedures § 57.14201 Conveyor start-up warnings. (a) When...

  12. 30 CFR 56.14201 - Conveyor start-up warnings.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Conveyor start-up warnings. 56.14201 Section 56.14201 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Equipment Safety Practices and Operational Procedures § 56.14201 Conveyor start-up warnings. (a) When...

  13. 30 CFR 57.14201 - Conveyor start-up warnings.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Conveyor start-up warnings. 57.14201 Section 57.14201 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Equipment Safety Practices and Operational Procedures § 57.14201 Conveyor start-up warnings. (a) When...

  14. 30 CFR 57.14201 - Conveyor start-up warnings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Conveyor start-up warnings. 57.14201 Section 57.14201 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Equipment Safety Practices and Operational Procedures § 57.14201 Conveyor start-up warnings. (a) When...

  15. 30 CFR 57.14201 - Conveyor start-up warnings.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Conveyor start-up warnings. 57.14201 Section 57.14201 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Equipment Safety Practices and Operational Procedures § 57.14201 Conveyor start-up warnings. (a) When...

  16. Startup analysis for a high temperature gas loaded heat pipe

    NASA Technical Reports Server (NTRS)

    Sockol, P. M.

    1973-01-01

    A model for the rapid startup of a high-temperature gas-loaded heat pipe is presented. A two-dimensional diffusion analysis is used to determine the rate of energy transport by the vapor between the hot and cold zones of the pipe. The vapor transport rate is then incorporated in a simple thermal model of the startup of a radiation-cooled heat pipe. Numerical results for an argon-lithium system show that radial diffusion to the cold wall can produce large vapor flow rates during a rapid startup. The results also show that startup is not initiated until the vapor pressure p sub v in the hot zone reaches a precise value proportional to the initial gas pressure p sub i. Through proper choice of p sub i, startup can be delayed until p sub v is large enough to support a heat-transfer rate sufficient to overcome a thermal load on the heat pipe.

  17. Spatial Burnout in Water Reactors with Nonuniform Startup Distributions of Uranium and Boron

    NASA Technical Reports Server (NTRS)

    Fox, Thomas A.; Bogart, Donald

    1955-01-01

    Spatial burnout calculations have been made of two types of water moderated cylindrical reactor using boron as a burnable poison to increase reactor life. Specific reactors studied were a version of the Submarine Advanced Reactor (sAR) and a supercritical water reactor (SCW) . Burnout characteristics such as reactivity excursion, neutron-flux and heat-generation distributions, and uranium and boron distributions have been determined for core lives corresponding to a burnup of approximately 7 kilograms of fully enriched uranium. All reactivity calculations have been based on the actual nonuniform distribution of absorbers existing during intervals of core life. Spatial burnout of uranium and boron and spatial build-up of fission products and equilibrium xenon have been- considered. Calculations were performed on the NACA nuclear reactor simulator using two-group diff'usion theory. The following reactor burnout characteristics have been demonstrated: 1. A significantly lower excursion in reactivity during core life may be obtained by nonuniform rather than uniform startup distribution of uranium. Results for SCW with uranium distributed to provide constant radial heat generation and a core life corresponding to a uranium burnup of 7 kilograms indicated a maximum excursion in reactivity of 2.5 percent. This compared to a maximum excursion of 4.2 percent obtained for the same core life when w'anium was uniformly distributed at startup. Boron was incorporated uniformly in these cores at startup. 2. It is possible to approach constant radial heat generation during the life of a cylindrical core by means of startup nonuniform radial and axial distributions of uranium and boron. Results for SCW with nonuniform radial distribution of uranium to provide constant radial heat generation at startup and with boron for longevity indicate relatively small departures from the initially constant radial heat generation distribution during core life. Results for SAR with a sinusoidal

  18. "Size Matters": Women in High Tech Start-Ups

    NASA Astrophysics Data System (ADS)

    Lackritz, Hilary

    2001-03-01

    For those who want constant excitement, change, and rapid opportunities to have an impact in the technical world, start-up companies offer wonderful challenges. This talk will focus realistically on rewards and risks in the start-up world. An outline of the differences between the high tech start-ups and the academic and consulting worlds from a personal viewpoint will be presented. Size usually does matter, and in this case, small size can equal independence, entrepreneurship, and other advantages that are hard to come by in Dilbert’s corporate world.

  19. Rapid Start-up and Loading of an Attached Growth, Simultaneous Nitrification/Denitrification Membrane Aerated Bioreactor

    NASA Technical Reports Server (NTRS)

    Meyer, Caitlin E.; Pensinger, Stuart; Pickering, Karen D.; Barta, Daniel; Shull, Sarah A.; Vega, Letticia M.; Christenson, Dylan; Jackson, W. Andrew

    2015-01-01

    Membrane aerated bioreactors (MABR) are attached-growth biological systems used for simultaneous nitrification and denitrification to reclaim water from waste. This design is an innovative approach to common terrestrial wastewater treatments for nitrogen and carbon removal and implementing a biologically-based water treatment system for long-duration human exploration is an attractive, low energy alternative to physiochemical processes. Two obstacles to implementing such a system are (1) the "start-up" duration from inoculation to steady-state operations and (2) the amount of surface area needed for the biological activity to occur. The Advanced Water Recovery Systems (AWRS) team at JSC explored these two issues through two tests; a rapid inoculation study and a wastewater loading study. Results from these tests demonstrate that the duration from inoculation to steady state can be reduced to under two weeks, and that despite low ammonium removal rates, the MABRs are oversized.

  20. 45 CFR 309.16 - What rules apply to start-up funding?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false What rules apply to start-up funding? 309.16... Procedures § 309.16 What rules apply to start-up funding? (a) The application for start-up funding under...-quarter estimate of expenditures for the start-up period; (ii) Notification of whether the Tribe or...

  1. 45 CFR 309.16 - What rules apply to start-up funding?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 2 2014-10-01 2012-10-01 true What rules apply to start-up funding? 309.16... Procedures § 309.16 What rules apply to start-up funding? (a) The application for start-up funding under...-quarter estimate of expenditures for the start-up period; (ii) Notification of whether the Tribe or...

  2. 45 CFR 309.16 - What rules apply to start-up funding?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true What rules apply to start-up funding? 309.16... Procedures § 309.16 What rules apply to start-up funding? (a) The application for start-up funding under...-quarter estimate of expenditures for the start-up period; (ii) Notification of whether the Tribe or...

  3. 45 CFR 309.16 - What rules apply to start-up funding?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 2 2012-10-01 2012-10-01 false What rules apply to start-up funding? 309.16... Procedures § 309.16 What rules apply to start-up funding? (a) The application for start-up funding under...-quarter estimate of expenditures for the start-up period; (ii) Notification of whether the Tribe or...

  4. USA/FBR program status FFTF operations startup experience

    SciTech Connect

    Moffitt, W.C.; Izatt, R.D.

    1981-06-01

    This paper gives highlights of the major Operations evaluations and operational results of the startup acceptance testing program and initiation of normal operating cycles for experiment irradiation in the FFTF. 33 figures. (DLC)

  5. Life Sciences Start-ups in Switzerland: CTI and its Support for Young Entrepreneurs.

    PubMed

    Sekanina, Klara

    2014-12-01

    According to the Global Entrepreneurship Monitor 2013, perceived opportunities to start a business in Switzerland are high and rank above average compared to other innovation-based countries. 2013 was a record year for start-ups in Switzerland. Around 40,000 new businesses were recorded in the commercial register and the trend is set to continue. There are two main criteria that lead to success, particularly for science- or technology- based start-ups: first of all, it is the business or product idea itself, and secondly it is the entrepreneurial team. CTI is supporting innovation in a manner that responds to a need in the market identified by industry. PMID:26508608

  6. Progress in Non-solenoidal Startup via Local Helicity Injection in the Pegasus Experiment

    NASA Astrophysics Data System (ADS)

    Fonck, R. J.; Barr, J. L.; Bongard, M. W.; Burke, M. G.; Hinson, E. T.; Perry, J. M.; Redd, A. J.; Schlossberg, D. J.; Schoenbeck, N. L.; Shriwise, P. C.; Thome, K. E.

    2012-10-01

    The operating space for localized helicity injection for non-solenoidal startup is constrained by helicity input and dissipation rates and a geometric limit on plasma current set by Taylor relaxation. To test the understanding of dissipation mechanisms during helicity-driven startup, the helicity injection startup and growth is being expanded to ˜0.3 MA plasma currents and longer pulse lengths on the Pegasus experiment. Following initiation via active current sources, passive electrodes can be used to grow discharges for relatively long pulse lengths. Bursts of MHD activity are observed during helicity injection, and correlate with rapid equilibrium changes, including inward motion of the magnetic axis, redistribution of the toroidal current, and strong ion heating with ion temperatures ˜1 keV observed. The plasma arc injector impedance and the associated helicity injection rate appear to be constrained by a double-layer space charge limit at low currents and by the Alfv'en-Lawson limit for strong electron beams at high currents. Additions to the experiment include an expanded poloidal field coil system for added plasma control, new divertor coils, new plasma gun-electrode injector assemblies, expanded gas fueling techniques, and eventually a doubling of the toroidal field.

  7. A Numerical Investigation of the Startup Transient in a Wave Rotor

    NASA Technical Reports Server (NTRS)

    Paxson, Daniel E.

    1996-01-01

    The startup process is investigated for a hypothetical four-port wave rotor, envisioned as a topping cycle for a small gas turbine engine. The investigation is conducted numerically using a multi-passage, one-dimensional CFD-based wave rotor simulation in combination with lumped volume models for the combustor, exhaust valve plenum, and rotor center cavity components. The simulation is described and several startup transients are presented which illustrate potential difficulties for the specific cycle design investigated. In particular it is observed that, prior to combustor light-off, or just after, the flow through the combustor loop is reversed from the design direction. The phenomenon is demonstrated and several possible modifications techniques are discussed which avoid or overcome the problem.

  8. The effectiveness of combined-cycle power plants hot startups simulating

    NASA Astrophysics Data System (ADS)

    Radin, Yu. A.; Kontorovich, T. S.; Molchanov, K. A.

    2015-09-01

    Activities aimed at substantiating the maneuverability characteristics of power-generating equipment installed at district heating power plants (DHPP) and especially at combined-cycle power plants (CCPPs) are quite topical for the modern conditions and involve calculations of thermally stressed state and analysis of the cyclic strength of steam path critical elements at different loading rates. Until recently, such problems have been solved in two possible ways: based on the results of tests carried out on operating equipment and using the mathematical models of heavily stressed parts of CCPP equipment. In this article, preference is given to the second way. The results of mathematical modeling represented as time dependences of the temperature state of equipment critical parts were taken as initial data for calculating their thermally stressed state and for analyzing their damageability according to the criterion of the equivalent operating hours. This criterion is an integral indicator characterizing the extent of damage accumulated in equipment parts and can be used for elaborating equipment maintenance programs. A dependence of the equivalent operating hours on the initial temperature of the metal of the high-pressure steam superheater's outlet header, the component imposing the strongest limitations on the power unit loading rate, is obtained. It is shown that the number of equivalent operating hours of the CCPP steam circuit part equipment accumulated during hot startups does not have any essential effect on the equipment service life (heat-recovery steam generators, steam turbine, and steam lines).

  9. Rapid Startup and Loading of an Attached Growth, Simultaneous Nitrification/Denitrification Membrane Aerated Bioreactor

    NASA Technical Reports Server (NTRS)

    Meyer, Caitlin; Vega, Leticia

    2014-01-01

    The Membrane Aerated Bioreactor (MABR) is an attached-growth biological system for simultaneous nitrification and denitrification. This design is an innovative approach to common terrestrial wastewater treatments for nitrogen and carbon removal. Implementing a biologically-based water treatment system for long-duration human exploration is an attractive, low energy alternative to physiochemical processes. Two obstacles to implementing such a system are (1) the "start-up" duration from inoculation to steady-state operations and (2) the amount of surface area needed for the biological activity to occur. The Advanced Water Recovery Systems (AWRS) team at JSC explored these two issues through two tests; a rapid inoculation study and a wastewater loading study. Results from these tests demonstrate that the duration from inoculation to steady state can be reduced to two weeks and that the surface area to volume ratio baseline used in the Alternative Water Processor (AWP) test was higher than what was needed to remove the organic carbon and ammonium from the system.

  10. [Quick Start-up and Sustaining of Shortcut Nitrification in Continuous Flow Reactor].

    PubMed

    Wu, Peng; Zhang Shi-ying; Song, Yin-ling; Xu, Yue-zhong; Shen, Yao-liang

    2016-04-15

    How to achieve fast and stable startup of shortcut nitrification has a very important practical value for treatment of low C/N ratio wastewater. Thus, the quick start-up and sustaining of shortcut nitrification were investigated in continuous flow reactor targeting at the current situation of urban wastewater treatment plant using a continuous flow process. The results showed that quick start-up of shortcut nitrification could be successfully achieved in a continuous flow reactor after 60 days' operation with intermittent aeration and controlling of three stages of stop/aeration time (15 min/45 min, 45 min/45 min and 30 min/30 min). The nitrification rates could reach 90% or 95% respectively, while influent ammonia concentrations were 50 or 100 mg · L⁻¹ with stop/aeration time of 30 min/30 min. In addition, intermittent aeration could inhibit the activity of nitrite oxidizing bacteria (NOB), while short hydraulic retention time (HRT) may wash out NOB. And a combined use of both measures was beneficial to sustain shortcut nitrification. PMID:27548971

  11. Analysis of start-up, retention, and adherence in ALS clinical trials

    PubMed Central

    Yerramilli-Rao, Padmaja; Szymonifka, Jackie; Yu, Hong; Kearney, Marianne; Grasso, Daniela; Deng, Jing; Levine-Weinberg, Mark; Shapiro, Jordan; Lee, Alexandra; Joseph, Lucia; Macklin, Eric A.; Cudkowicz, Merit E.

    2013-01-01

    Objective: To investigate predictors of trial start-up times, high attrition, and poor protocol adherence in amyotrophic lateral sclerosis (ALS) trials. Methods: Retrospective analysis of start-up times, retention, and protocol adherence was performed on 5 clinical studies conducted by the Northeast ALS Consortium and 50 ALS clinical trials identified by PubMed search. Predictors of start-up times were estimated by accelerated failure time models with random effects. Predictors of retention and protocol deviations were estimated by mixed-model logistic regression. Results: Median times for contract execution and institutional review board (IRB) approval were 105 days and 125 days, respectively. Contract execution was faster at sites with more ongoing trials (p = 0.005), and more full-time (p = 0.006) and experienced (p < 0.001) coordinators. IRB approval was faster at sites with more ongoing trials (p = 0.010) and larger ALS clinics (p = 0.038). Site activation after IRB approval was faster at sites with more full-time (p = 0.038) and experienced (p < 0.001) coordinators. Twenty-two percent of surviving participants withdrew before completing the trial. Better participant functional score at baseline was an independent predictor of trial completion (odds ratio 1.29, p = 0.002) and fewer protocol deviations (odds ratio 0.86, p = 0.030). Conclusion: Delays in IRB review contribute the most to prolonged trial start-up times, and these timelines are faster in sites with more experienced staff. Strategies to improve protocol adherence and participants' retention may include enrolling people at early disease stages. PMID:24005339

  12. Pinon Pine power project nears start-up

    SciTech Connect

    Tatar, G.A.; Gonzalez, M.; Mathur, G.K.

    1997-12-31

    The IGCC facility being built by Sierra Pacific Power Company (SPPCo) at their Tracy Station in Nevada is one of three IGCC facilities being cost-shared by the US Department of Energy (DOE) under their Clean Coal Technology Program. The specific technology to be demonstrated in SPPCo`s Round Four Project, known as the Pinon Pine IGCC Project, includes the KRW air blown pressurized fluidized bed gasification process with hot gas cleanup coupled with a combined cycle facility based on a new GE 6FA gas turbine. Construction of the 100 MW IGCC facility began in February 1995 and the first firing of the gas turbine occurred as scheduled on August 15, 1996 with natural gas. Mechanical completion of the gasifier and other outstanding work is due in January 1997. Following the startup of the plant, the project will enter a 42 month operating and testing period during which low sulfur western and high sulfur eastern or midwestern coals will be processed.

  13. Resonance investigation of pump-turbine during startup process

    NASA Astrophysics Data System (ADS)

    He, L. Y.; Wang, Z. W.; Kurosawa, S.; Nakahara, Y.

    2014-12-01

    The causes of resonance of a certain model pump-turbine unit during startup process were investigated in this article. A three-dimensional full flow path analysis model which contains spiral case, stay vanes, guide vanes, runner, gaps outside the runner crown and band, and draft tube was constructed. The transient hydraulic excitation force of full flow path was analyzed under five conditions near the resonance region. Based on one-way fluid- structure interaction (FSI) analysis model, the dynamic stress characteristics of the pump-turbine runner was investigated. The results of pressure pulsation, vibration mode and dynamic stress obtained from simulation were consistent with the test results. The study indicated that the hydraulic excitation frequency (Zg*fn) Hz due to rotor-stator interference corresponding to the natural frequency of 2ND+4ND runner mode is the main cause of resonance. The relationship among pressure pulsation, vibration mode and dynamic stress was discussed in this paper. The results revealed the underlying causes of the resonance phenomenon.

  14. Resonance investigation of pump-turbine during startup process

    NASA Astrophysics Data System (ADS)

    Y He, L.; Wang, Z. W.; Kurosawa, S.; Nakahara, Y.

    2014-03-01

    The causes of resonance of a certain model pump-turbine unit during startup process were investigated in this article. A three-dimensional full flow path analysis model which contains spiral case, stay vanes, guide vanes, runner, gaps outside the runner crown and band, and draft tube was constructed. The transient hydraulic excitation force of full flow path was analyzed under five conditions near the resonance region. Based on one-way fluid- structure interaction (FSI) analysis model, the dynamic stress characteristics of the pump-turbine runner was investigated. The results of pressure pulsation, vibration mode and dynamic stress obtained from simulation were consistent with the test results. The study indicated that the hydraulic excitation frequency (Zg*fn) Hz due to rotor-stator interference corresponding to the natural frequency of 2ND+4ND runner mode is the main cause of resonance. The relationship among pressure pulsation, vibration mode and dynamic stress was discussed in this paper. The results revealed the underlying causes of the resonance phenomenon.

  15. Using activity-based costing in surgery.

    PubMed

    Grandlich, Cheryl

    2004-01-01

    ACTIVITY-BASED COSTING is an accounting technique that allows organizations to determine actual costs associated with their services based on the resources they consume. THIS TECHNIQUE can be used in a variety of ways, including targeting high-cost activities, forecasting financial baselines, and supporting resource allocation. FOUR STEPS should be followed when applying activity-based costing to surgical procedures. THIS ARTICLE explores how Froedtert Memorial Lutheran Hospital, Milwaukee, used activity-based costing.

  16. A Data Scientist's Guide to Start-Ups.

    PubMed

    Provost, Foster; Webb, Geoffrey I; Bekkerman, Ron; Etzioni, Oren; Fayyad, Usama; Perlich, Claudia

    2014-09-01

    In August 2013, we held a panel discussion at the KDD 2013 conference in Chicago on the subject of data science, data scientists, and start-ups. KDD is the premier conference on data science research and practice. The panel discussed the pros and cons for top-notch data scientists of the hot data science start-up scene. In this article, we first present background on our panelists. Our four panelists have unquestionable pedigrees in data science and substantial experience with start-ups from multiple perspectives (founders, employees, chief scientists, venture capitalists). For the casual reader, we next present a brief summary of the experts' opinions on eight of the issues the panel discussed. The rest of the article presents a lightly edited transcription of the entire panel discussion.

  17. Transient CFD simulation of a Francis turbine startup

    NASA Astrophysics Data System (ADS)

    Nicolle, J.; Morissette, J. F.; Giroux, A. M.

    2012-11-01

    To assess the life expectancy of hydraulic turbines, it is essential to obtain the loading on the blades, especially during transient operations known to be the most damaging. This paper presents a simplified CFD setup to model the startup phase of a Francis turbine while it goes from rest to speed no-load condition. The fluid domain included one distributor sector coupled with one runner passage. The guide vane motion and change in the angular velocity were included in a commercial code with user functions. Comparisons between numerical results and measurements acquired on a full-size turbine showed that most of the flow physics occurring during startup were captured.

  18. Calculations of the startup experiments at the Poolside Facility

    SciTech Connect

    Williams, M.L.; Maerker, R.E.

    1982-01-01

    Discrete ordinate calculations are made and the results compared with measurements performed in the startup experiment at the Poolside Facility. Because of the physical size of the simulated surveillance capsule used in this experiment, the analytic procedure is more complicated than one adopted in earlier calculations of the PCA-PVF and PSF. The comparisons indicate the pressure vessel fluences in the long-term irradiation experiments still presently going on at the PSF, and which are geometrically identical to the startup experiment, can only be predicted to within about 20%.

  19. Prediction of the start-up characteristics of thermionic converter in a STAR-C reactor

    NASA Astrophysics Data System (ADS)

    Lieb, David P.; Witt, Carl A.; Miskolczy, Garbor; Lee, Celia C. M.; McVey, John

    1992-01-01

    of the collector heat pipe system to warm the collector without requiring electron heating. The heat transfer characteristics of the heat pipe are partially responsible for this behavior since the cooling does not become active until the reservoir temperature is high enough to generate cesium pressure. Thus the thermal time constraints of the converter-reservior system are well within the 60 minute requirements and will not be a limiting factor for rapid start-up of the system.

  20. Experiments and modeling on FTU tokamak for EC assisted plasma start-up studies in ITER-like configuration

    NASA Astrophysics Data System (ADS)

    Granucci, G.; Garavaglia, S.; Ricci, D.; Artaserse, G.; Belli, F.; Bin, W.; Calabrò, G.; Cavinato, M.; Farina, D.; Figini, L.; Moro, A.; Ramogida, G.; Sozzi, C.; Tudisco, O.; FTU Team

    2015-09-01

    The intrinsic limited toroidal electric field (0.3 V m-1) in devices with superconducting poloidal coils (ITER, JT-60SA) requires additional heating, like electron cyclotron (EC) waves, to initiate plasma and to sustain it during the burn-through phase. The FTU tokamak has contributed to studying the perspective of EC assisted plasma breakdown. Afterward, a new experimental and modeling activity addressing the study of assisted plasma start-up in a configuration close to the ITER one (magnetic field, oblique injection, and polarization) has been performed and is presented here. These experiments have been supported by a 0D code, BKD0, developed to model the plasma start-up and linked to a beam tracing code computing, in a consistent way, EC absorption. The FTU results demonstrate the role of polarization conversion at the inner wall reflection. Dedicated experiments also showed the capability of EC power to sustain plasma start-up in the presence of strong error field (12 mT), with a null outside the vacuum vessel. The BKD0 code, applied to FTU data, has been used to determine the operational window of sustained breakdown as a function of toroidal electric field and neutral pressure. Experimental results in agreement with the BKD0 simulations support the use of the code to predict start-up in future tokamaks, like ITER and JT60SA.

  1. Activity Based Curriculum for Elementary Education. Additional Activities, K-6.

    ERIC Educational Resources Information Center

    Wichita Public Schools, KS.

    This elementary curriculum is a vehicle to provide manipulative activities that reinforce academic skills through meaningful, relevant, activity-based awareness of modern society. The twenty-six activity plans included in the curriculum place a major emphasis upon realistic or concrete experiences that deal with the manipulation and exploration of…

  2. Beta: An Experiment in Funded Undergraduate Start-Up

    ERIC Educational Resources Information Center

    Jones, Paul; Forbes-Simpson, Kellie; Maas, Gideon; Newbery, Robert

    2015-01-01

    This paper reports on an evaluation of a funded undergraduate project designed to enable student business start-up. The programme, entitled "Beta", provides undergraduate students with £1,500 of seed-corn funding. The key objective of the project is for the participants to exit it with a viable and legal business entity through which…

  3. Creating Start-up Companies around NCI Inventions | Poster

    Cancer.gov

    By Karen Surabian, Thomas Stackhouse, and Rose Freel, Contributing Writers, and Rosemarie Truman, Guest Writer The National Cancer Institute (NCI), led by the Technology Transfer Center (TTC),  the Avon Foundation, and The Center for Advancing Innovation have partnered to create a “first-of-a-kind” Breast Cancer Start-up Challenge.

  4. Success of Breast Cancer Startup Challenge Inspires Second Challenge | Poster

    Cancer.gov

    By Thomas Stackhouse, Joseph Conrad, and Michele Newton, Contributing Writers, and Rosemarie Truman, Guest Writer Sixty-one teams have been accepted into, and are now competing in, the Neuro Startup Challenge, a new collaboration established by the National Institutes of Health (NIH) with The Center for Advancing Innovation (CAI) and Heritage Provider Network, Inc.

  5. Start-Up Rhetoric in Eight Speeches of Barack Obama

    ERIC Educational Resources Information Center

    O'Connell, Daniel C.; Kowal, Sabine; Sabin, Edward J.; Lamia, John F.; Dannevik, Margaret

    2010-01-01

    Our purpose in the following was to investigate the start-up rhetoric employed by U.S. President Barack Obama in his speeches. The initial 5 min from eight of his speeches from May to September of 2009 were selected for their variety of setting, audience, theme, and purpose. It was generally hypothesized that Barack Obama, widely recognized for…

  6. 40 CFR 68.77 - Pre-startup review.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.77 Pre-startup review. (a) The... stationary sources when the modification is significant enough to require a change in the process safety... change, § 68.75. (4) Training of each employee involved in operating a process has been completed....

  7. Start-Up Strategies for Speaking and Listening across Disciplines.

    ERIC Educational Resources Information Center

    Weiss, Robert O.

    To document procedures used in the early stages of introducing programs of Speaking and Listening across Disciplines (SALAD) in higher education, this descriptive report examines the "start-up" strategies for SALAD in eight institutions: Alverno College (Wisconsin), Central College (Iowa), Clarkson University (New York), DePauw University…

  8. A Boom Time for Education Start-Ups

    ERIC Educational Resources Information Center

    DeSantis, Nick

    2012-01-01

    Harsh economic realities mean trouble for college leaders. But where administrators perceive an impending crisis, investors increasingly see opportunity. In recent years, venture capitalists have poured millions into education-technology start-ups, trying to cash in on a market they see as ripe for a digital makeover. And lately, those wagers have…

  9. 40 CFR 68.77 - Pre-startup review.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.77 Pre-startup review. (a) The... stationary sources when the modification is significant enough to require a change in the process safety... change, § 68.75. (4) Training of each employee involved in operating a process has been completed....

  10. Data base management systems activities

    NASA Technical Reports Server (NTRS)

    1983-01-01

    The Data Management System-1100 is designed to operate in conjunction with the UNIVAC 1100 Series Operating System on any 1100 Series computer. DMS-1100 is divided into the following four major software components: (1) Data Definition Languages (DDL); (2) Data Management Routine (DMR); (3) Data Manipulation Languages (DML); and (4) Data Base Utilities (DBU). These software components are described in detail.

  11. Non-solenoidal Startup through Local Helicity Injection in the Pegasus Toroidal Experiment

    NASA Astrophysics Data System (ADS)

    Bongard, M. W.; Barr, J. L.; Burke, M. G.; Fonck, R. J.; Hinson, E. T.; Perry, J. M.; Redd, A. J.; Schlossberg, D. J.; Schoenbeck, N. L.; Shriwise, P. C.; Thome, K. E.

    2012-10-01

    Non-solenoidal plasma startup via local helicity injection is governed by helicity balance and Taylor relaxation constraints. Local helicity injection capabilities at Pegasus have been increased, supporting an expansion of the existing operational space towards Ip˜ 0.3 MA and characterization of helicity dissipation mechanisms during plasma startup, growth, and sustainment. After discharge initiation with an active current source, helicity injection may be provided by passive electrodes to continue its evolution and extend pulse length. Local magnetic measurements confirm that a local field null is transiently created by injected current streams prior to relaxation into a tokamak-like state and sustained helicity injection. Bursts of MHD activity during the growth phase are correlated with rapid equilibrium changes, redistribution of the toroidal current density, and observations of strong ion heating (Ti ˜ 1 keV). The impedance of active injectors and thereby their helicity input rate appears constrained by a double-layer space charge limit at low currents and the Alfv'en-Lawson limit for intense electron beams at high currents. Facility and diagnostic upgrades include an expanded poloidal field coil system for improved plasma control, new divertor coils, new plasma gun-electrode injector assemblies, a Thomson scattering system, expanded gas fueling techniques, and support for doubling the toroidal field.

  12. Non-solenoidal Startup via Local Helicity Injection on Pegasus: Progress and Plans

    NASA Astrophysics Data System (ADS)

    Reusch, J. A.; Barr, J. L.; Bodner, G. M.; Bongard, M. W.; Burke, M. G.; Fonck, R. J.; Hinson, E. T.; Lewicki, B. T.; Perry, J. M.; Schlossberg, D. J.

    2015-11-01

    Non-solenoidal plasma startup via local helicity injection (LHI) at the Pegasus toroidal experiment now provides routine operation at Ip ~ 0.17MA with Iinj ~ 5kA and Vinj ~ 1kV from four active arc injectors. Experiments in the past year have advanced the understanding of the governing physics of LHI and its supporting technology. Injector impedance scales as Vinj3/ 2 and is governed by two effects: a quasineutrality constraint on electron beam propagation, related to the tokamak edge density, and double-layer sheath expansion, related to narc. Injector design improvements permit operation at Vinj >= 1 kV without deleterious PMI or impurity generation. Discharges with varied shape, Ip(t), and helicity input test a predictive 0D power-balance model for LHI startup. Anomalous, reconnection-driven Ti >800 eV and strong MHD activity localized near the injectors are observed during LHI. Preliminary core Thomson scattering measurements indicate surprisingly high Te >300 eV, which if verified may indicate the dominance of high-energy electron fueling from the injector current streams. A new divertor injector system has been designed to substantially increase the available helicity input rate and support critical studies of confinement during LHI and reconnection activity at high Ip. A proposed upgrade to the Pegasus experiment will extend these studies to NSTX-U relevant parameters. Support: US DOE grants DE-FG02-96ER54375; and DE-SC0006928.

  13. Start-up and stabilization of an Anammox process from a non-acclimatized sludge in CSTR.

    PubMed

    Bagchi, Samik; Biswas, Rima; Nandy, Tapas

    2010-09-01

    Development of an Anammox (anaerobic ammonium oxidation) process using non-acclimatized sludge requires a long start-up period owing to the very slow growth rate of Anammox bacteria. This article addresses the issue of achieving a shorter start-up period for Anammox activity in a well-mixed continuously stirred tank reactor (CSTR) using non-acclimatized anaerobic sludge. Proper selection of enrichment conditions and low stirring speed of 30 +/- 5 rpm resulted in a shorter start-up period (82 days). Activity tests revealed the microbial community structure of Anammox micro-granules. Ammonia-oxidizing bacteria (AOB) were found on the surface and on the outer most layers of granules while nitrite-oxidizing bacteria (NOB) and Anammox bacteria were present inside. Fine-tuning of influent NO2(-)/NH4+ ratio allowed Anammox activity to be maintained when mixed microbial populations were present. The maximum nitrogen removal rate achieved in the system was 0.216 kg N/(m(3) day) with a maximum specific nitrogen removal rate of 0.434 g N/(g VSS day). During the study period, Anammox activity was not inhibited by pH changes and free ammonia toxicity.

  14. Start-up and stabilization of an Anammox process from a non-acclimatized sludge in CSTR.

    PubMed

    Bagchi, Samik; Biswas, Rima; Nandy, Tapas

    2010-09-01

    Development of an Anammox (anaerobic ammonium oxidation) process using non-acclimatized sludge requires a long start-up period owing to the very slow growth rate of Anammox bacteria. This article addresses the issue of achieving a shorter start-up period for Anammox activity in a well-mixed continuously stirred tank reactor (CSTR) using non-acclimatized anaerobic sludge. Proper selection of enrichment conditions and low stirring speed of 30 +/- 5 rpm resulted in a shorter start-up period (82 days). Activity tests revealed the microbial community structure of Anammox micro-granules. Ammonia-oxidizing bacteria (AOB) were found on the surface and on the outer most layers of granules while nitrite-oxidizing bacteria (NOB) and Anammox bacteria were present inside. Fine-tuning of influent NO2(-)/NH4+ ratio allowed Anammox activity to be maintained when mixed microbial populations were present. The maximum nitrogen removal rate achieved in the system was 0.216 kg N/(m(3) day) with a maximum specific nitrogen removal rate of 0.434 g N/(g VSS day). During the study period, Anammox activity was not inhibited by pH changes and free ammonia toxicity. PMID:20549296

  15. Startup of large-scale projects casts spotlight on IGCC

    SciTech Connect

    Swanekamp, R.

    1996-06-01

    With several large-scale plants cranking up this year, integrated coal gasification/combined cycle (IGCC) appears poised for growth. The technology may eventually help coal reclaim its former prominence in new plant construction, but developers worldwide are eyeing other feedstocks--such as petroleum coke or residual oil. Of the so-called advanced clean-coal technologies, integrated (IGCC) appears to be having a defining year. Of three large-scale demonstration plants in the US, one is well into startup, a second is expected to begin operating in the fall, and a third should startup by the end of the year; worldwide, over a dozen more projects are in the works. In Italy, for example, several large projects using petroleum coke or refinery residues as feedstocks are proceeding, apparently on a project-finance basis.

  16. The start-up of the bi-provincial upgrader

    SciTech Connect

    Chase, S.

    1995-12-31

    The Bi-Provincial Upgrader is a $1.63 x 10{sup 9} Cdn grass-roots heavy oil upgrading facility located near Lloydminster, Saskatchewan. The facility, which started operation in August 1992, is designed to produce 7300 m{sup 3}/day of 34{degrees}API synthetic crude from 11-15{degrees}API heavy crude oils. The start-up and initial operation of the facility has been a technical success. The facility reached design capacity in a much shorter time than typically reported for the start-up of similar units and has operated reliably at better than design capacity. In this paper, the plant operating performance is reviewed in some detail. A review of the engineering and construction phases and a summary of regional benefits is also included.

  17. The construction, startup and operation of the repowered Wabash River coal gasification project

    SciTech Connect

    Roll, M.W.

    1995-12-31

    The Wabash River Coal Gasification Repowering Project (the Project) is a joint venture to design, construct, own, and operate a commercial integrated coal gasification combined cycle (IGCC) power plant at PSI`s Wabash River Generating Station in West Terre Haute, Indiana. The IGCC power plant will produce a nominal 262 (net) MW of clean, energy efficient capacity for PSI`s customers. The Project will use locally mined high sulfur coal, at an extremely competitive price, and outperform Phase 2 requirements of the Clean Air Act Amendments. The net plant heat rate will be below 9,000 Btu/kwh (HHV), SO{sub 2} emissions are expected to be 0.02 lbs/MMBtu of fuel and NOx are expected to be 0.08 lbs/MMBtu. Upon startup in 1995, the Project will be the largest operating single-train coal gasification combined cycle plant in the World. The paper gives a history of the project then describes the design, cost and efficiency, environmental benefits, construction activities, startup and commissioning activities, and the major challenges facing the Project.

  18. Spent Nuclear Fuel (SNF) Startup Plan to Operations

    SciTech Connect

    GREGORY, J.R.

    2000-10-11

    This plan defines the approach that will be used to ensure the transition from initial startup to normal operations of the SNF operations--are performed in a safe, controlled, and deliberate manner. It provides a phased approach that bridges the operations between the completion of the ORR and the return to normal operations. This plan includes management oversight and administrative controls to be implemented and then reduced in a controlled manner until normal operations are authorized by SNF Management.

  19. Fusion core start-up, ignition and burn simulations of reversed-field pinch (RFP) reactors

    SciTech Connect

    Chu, Yuh-Yi

    1988-01-01

    A transient reactor simulation model is developed to investigate and simulate the start-up, ignition and burn of a reversed-field pinch reactor. The simulation is based upon a spatially averaged plasma balance model with field profiles obtained from MHD quasi-equilibrium analysis. Alpha particle heating is estimated from Fokker-Planck calculations. The instantaneous plasma current is derived from a self-consistent circuit analysis for plasma/coil/eddy current interactions. The simulation code is applied to the TITAN RFP reactor design which features a compact, high-power-density reversed-field pinch fusion system. A contour analysis is performed using the steady-state global plasma balance. The results are presented with contours of constant plasma current. A saddle point is identified in the contour plot which determines the minimum value of plasma current required to achieve ignition. An optimized start-up to ignition and burn path can be obtained by passing through the saddle point. The simulation code is used to study and optimize the start-up scenario. In the simulations of the TITAN RFP reactor, the OH-driven superconducting EF coils are found to deviate from the required equilibrium values as the induced plasma current increases. This results in the modification of superconducting EF coils and the addition of a set of EF trim coils. The design of the EF coil system is performed with the simulation code subject to the optimization of trim-coil power and current. In addition, the trim-coil design is subject to the constraints of vertical-field stability index and maintenance access. A power crowbar is also needed to prevent the superconducting EF coils from generating excessive vertical field. A set of basic results from the simulation of TITAN RFP reactor yield a picture of RFP plasma operation in a reactor. Investigations of eddy current are also presented. 145 refs., 37 figs., 2 tabs.

  20. Enhanced start-up of anaerobic facultatively autotrophic biocathodes in bioelectrochemical systems.

    PubMed

    Zaybak, Zehra; Pisciotta, John M; Tokash, Justin C; Logan, Bruce E

    2013-12-01

    Biocathodes in bioelectrochemical systems (BESs) can be used to convert CO2 into diverse organic compounds through a process called microbial electrosynthesis. Unfortunately, start-up of anaerobic biocathodes in BESs is a difficult and time consuming process. Here, a pre-enrichment method was developed to improve start-up of anaerobic facultatively autotrophic biocathodes capable of using cathodes as the electron donor (electrotrophs) and CO2 as the electron acceptor. Anaerobic enrichment of bacteria from freshwater bog sediment samples was first performed in batch cultures fed with glucose and then used to inoculate BES cathode chambers set at -0.4V (versus a standard hydrogen electrode; SHE). After two weeks of heterotrophic operation of BESs, CO2 was provided as the sole electron acceptor and carbon source. Consumption of electrons from cathodes increased gradually and was sustained for about two months in concert with a significant decrease in cathode chamber headspace CO2. The maximum current density consumed was -34 ± 4 mA/m(2). Biosynthesis resulted in organic compounds that included butanol, ethanol, acetate, propionate, butyrate, and hydrogen gas. Bacterial community analyses based on 16S rRNA gene clone libraries revealed Trichococcus palustris DSM 9172 (99% sequence identity) as the prevailing species in biocathode communities, followed by Oscillibacter sp. and Clostridium sp. Isolates from autotrophic cultivation were most closely related to Clostridium propionicum (99% sequence identity; ZZ16), Clostridium celerecrescens (98-99%; ZZ22, ZZ23), Desulfotomaculum sp. (97%; ZZ21), and Tissierella sp. (98%; ZZ25). This pre-enrichment procedure enables simplified start-up of anaerobic biocathodes for applications such as electrofuel production by facultatively autotrophic electrotrophs.

  1. Enhanced start-up of anaerobic facultatively autotrophic biocathodes in bioelectrochemical systems.

    PubMed

    Zaybak, Zehra; Pisciotta, John M; Tokash, Justin C; Logan, Bruce E

    2013-12-01

    Biocathodes in bioelectrochemical systems (BESs) can be used to convert CO2 into diverse organic compounds through a process called microbial electrosynthesis. Unfortunately, start-up of anaerobic biocathodes in BESs is a difficult and time consuming process. Here, a pre-enrichment method was developed to improve start-up of anaerobic facultatively autotrophic biocathodes capable of using cathodes as the electron donor (electrotrophs) and CO2 as the electron acceptor. Anaerobic enrichment of bacteria from freshwater bog sediment samples was first performed in batch cultures fed with glucose and then used to inoculate BES cathode chambers set at -0.4V (versus a standard hydrogen electrode; SHE). After two weeks of heterotrophic operation of BESs, CO2 was provided as the sole electron acceptor and carbon source. Consumption of electrons from cathodes increased gradually and was sustained for about two months in concert with a significant decrease in cathode chamber headspace CO2. The maximum current density consumed was -34 ± 4 mA/m(2). Biosynthesis resulted in organic compounds that included butanol, ethanol, acetate, propionate, butyrate, and hydrogen gas. Bacterial community analyses based on 16S rRNA gene clone libraries revealed Trichococcus palustris DSM 9172 (99% sequence identity) as the prevailing species in biocathode communities, followed by Oscillibacter sp. and Clostridium sp. Isolates from autotrophic cultivation were most closely related to Clostridium propionicum (99% sequence identity; ZZ16), Clostridium celerecrescens (98-99%; ZZ22, ZZ23), Desulfotomaculum sp. (97%; ZZ21), and Tissierella sp. (98%; ZZ25). This pre-enrichment procedure enables simplified start-up of anaerobic biocathodes for applications such as electrofuel production by facultatively autotrophic electrotrophs. PMID:24126154

  2. Long pulse EBW start-up experiments in MAST

    SciTech Connect

    Shevchenko, V. F.; Baranov, Y. F.; Bigelow, T.; Caughman, J. B.; Diem, S.; Dukes, C.; Finburg, P.; Hawes, J.; Gurl, C.; Griffiths, J.; Mailloux, J.; Peng, M.; Saveliev, A. N.; Takase, Y.; Tanaka, H.; Taylor, G.

    2015-03-12

    Start-up technique reported here relies on a double mode conversion (MC) for electron Bernstein wave (EBW) excitation. It consists of MC of the ordinary (O) mode, entering the plasma from the low field side of the tokamak, into the extraordinary (X) mode at a mirror-polarizer located at the high field side. The X mode propagates back to the plasma, passes through electron cyclotron resonance (ECR) and experiences a subsequent X to EBW MC near the upper hybrid resonance (UHR). Finally the excited EBW mode is totally absorbed at the Doppler shifted ECR. The absorption of EBW remains high even in cold rarefied plasmas. Furthermore, EBW can generate significant plasma current giving the prospect of a fully solenoid-free plasma start-up. First experiments using this scheme were carried out on MAST [1]. Plasma currents up to 33 kA have been achieved using 28 GHz 100kW 90ms RF pulses. Recently experimental results were extended to longer RF pulses showing further increase of plasma currents generated by RF power alone. A record current of 73kA has been achieved with 450ms RF pulse of similar power. The current drive enhancement was mainly achieved due to RF pulse extension and further optimisation of the start-up scenario.

  3. Long pulse EBW start-up experiments in MAST

    DOE PAGES

    Shevchenko, V. F.; Baranov, Y. F.; Bigelow, T.; Caughman, J. B.; Diem, S.; Dukes, C.; Finburg, P.; Hawes, J.; Gurl, C.; Griffiths, J.; et al

    2015-03-12

    Start-up technique reported here relies on a double mode conversion (MC) for electron Bernstein wave (EBW) excitation. It consists of MC of the ordinary (O) mode, entering the plasma from the low field side of the tokamak, into the extraordinary (X) mode at a mirror-polarizer located at the high field side. The X mode propagates back to the plasma, passes through electron cyclotron resonance (ECR) and experiences a subsequent X to EBW MC near the upper hybrid resonance (UHR). Finally the excited EBW mode is totally absorbed at the Doppler shifted ECR. The absorption of EBW remains high even inmore » cold rarefied plasmas. Furthermore, EBW can generate significant plasma current giving the prospect of a fully solenoid-free plasma start-up. First experiments using this scheme were carried out on MAST [1]. Plasma currents up to 33 kA have been achieved using 28 GHz 100kW 90ms RF pulses. Recently experimental results were extended to longer RF pulses showing further increase of plasma currents generated by RF power alone. A record current of 73kA has been achieved with 450ms RF pulse of similar power. The current drive enhancement was mainly achieved due to RF pulse extension and further optimisation of the start-up scenario.« less

  4. Long Pulse EBW Start-up Experiments in MAST

    NASA Astrophysics Data System (ADS)

    Shevchenko, V. F.; Baranov, Y. F.; Bigelow, T.; Caughman, J. B.; Diem, S.; Dukes, C.; Finburg, P.; Hawes, J.; Gurl, C.; Griffiths, J.; Mailloux, J.; Peng, M.; Saveliev, A. N.; Takase, Y.; Tanaka, H.; Taylor, G.

    2015-03-01

    Start-up technique reported here relies on a double mode conversion (MC) for electron Bernstein wave (EBW) excitation. It consists of MC of the ordinary (O) mode, entering the plasma from the low field side of the tokamak, into the extraordinary (X) mode at a mirror-polarizer located at the high field side. The X mode propagates back to the plasma, passes through electron cyclotron resonance (ECR) and experiences a subsequent X to EBW MC near the upper hybrid resonance (UHR). Finally the excited EBW mode is totally absorbed at the Doppler shifted ECR. The absorption of EBW remains high even in cold rarefied plasmas. Furthermore, EBW can generate significant plasma current giving the prospect of a fully solenoid-free plasma start-up. First experiments using this scheme were carried out on MAST [1]. Plasma currents up to 33 kA have been achieved using 28 GHz 100kW 90ms RF pulses. Recently experimental results were extended to longer RF pulses showing further increase of plasma currents generated by RF power alone. A record current of 73kA has been achieved with 450ms RF pulse of similar power. The current drive enhancement was mainly achieved due to RF pulse extension and further optimisation of the start-up scenario.

  5. Why activity-based costing works.

    PubMed

    Gabram, S G; Mendola, R A; Rozenfeld, J; Gamelli, R L

    1997-01-01

    With advancing technology and the quest for delineating the true cost of a procedure or diagnostic test, cost accounting techniques are being re-explored in the health care setting. Activity-based costing (ABC), adopted from other businesses, is one such example that has applications in the health industry. The purpose of this paper is to enhance the understanding of health care costs among physician providers, emphasizing a new approach--activity-based costing. PMID:10169347

  6. Why activity-based costing works.

    PubMed

    Gabram, S G; Mendola, R A; Rozenfeld, J; Gamelli, R L

    1997-01-01

    With advancing technology and the quest for delineating the true cost of a procedure or diagnostic test, cost accounting techniques are being re-explored in the health care setting. Activity-based costing (ABC), adopted from other businesses, is one such example that has applications in the health industry. The purpose of this paper is to enhance the understanding of health care costs among physician providers, emphasizing a new approach--activity-based costing.

  7. The activated sludge process: Fundamentals of operation

    SciTech Connect

    Junkins, R.; Deeny, K.J.; Eckhoff, T.H.

    1983-01-01

    The procedures given here - based on extensive and intensive experience. Background information on process mechanics is followed by detailed consideration of control and troubleshooting practices. Contents: PREFACE AND INTRODUCTION; PROCESS MECHANICS; Basic Mechanism of Activated Sludge Systems; Formation of Activated Sludge; Growth of Microorganisms; Classifications of Microorganisms: Type, Environment, Age; Solids Separation and Return; FACTORS AFFECTING OPERATION; Raw Wastewater Strength; Dissolved Oxygen; pH; Temperature; Nutrients; Toxicity; Mixing; Detention Time; Hydraulics; PROCESS MODIFICATIONS; Conventional; Complete Mix; Contact-Stabilization; Extended Aeration; Others; PROCESS MONITORING; Visual; Analytical Indicators; OPERATIONAL CONTROL; Sludge Volume Index; Sludge Age; Mean Cell Residence Time; Food/Microorganism Ratio; Organic Loading Rate; Solids Loading Rate; Clarifier Overflow Rate; Weir Overflow Rate; Sludge Recycle Rate, Sludge Wastage Rate; Chemical Feed Rate; TROUBLESHOOTING; Low BOD Removal; Low D.O. in Aeration Baisn; Poor Settling; PLANT START-UP; Introduction; Pre Start-up Checkup; Wastewater Analysis; Seed Screening; Process Checklist; Mechanical Checklist; Familiarization and Training; Start-up; Seeding; Process Monitoring; Transition; Typical Start-up Problems; Foaming; Settling Problems; Low BOD Removal; INDEX.

  8. Startup and oxygen concentration effects in a continuous granular mixed flow autotrophic nitrogen removal reactor.

    PubMed

    Varas, Rodrigo; Guzmán-Fierro, Víctor; Giustinianovich, Elisa; Behar, Jack; Fernández, Katherina; Roeckel, Marlene

    2015-08-01

    The startup and performance of the completely autotrophic nitrogen removal over nitrite (CANON) process was tested in a continuously fed granular bubble column reactor (BCR) with two different aeration strategies: controlling the oxygen volumetric flow and oxygen concentration. During the startup with the control of oxygen volumetric flow, the air volume was adjusted to 60mL/h and the CANON reactor had volumetric N loadings ranging from 7.35 to 100.90mgN/Ld with 36-71% total nitrogen removal and high instability. In the second stage, the reactor was operated at oxygen concentrations of 0.6, 0.4 and 0.2mg/L. The best condition was 0.2 mgO2/L with a total nitrogen removal of 75.36% with a CANON reactor activity of 0.1149gN/gVVSd and high stability. The feasibility and effectiveness of CANON processes with oxygen control was demonstrated, showing an alternative design tool for efficiently removing nitrogen species.

  9. Stratified ecology techniques in the startup of an anaerobic downflow fixed film percolating reactor

    SciTech Connect

    Canovas-Diaz, M.; Howell, J.A.

    1987-01-01

    A two-column pilot scale downflow percolating fixed film (DPFF) anaerobic reactor treating deproteinized cheese whey (DPW) was used in this study. The system was operated at one-third of the maximum working volume in an attempt to avoid mass transfer limitations of the gas products (since two-thirds of the immobilized microbial culture was unsubmerged), as well as to minimize the effects of localized high volatile fatty acids (VFA) levels and low pH on its methanogenic activity. A new method to shorten the start-up period was used by growing methanogenic and acetogenic (H2-producers) bacteria on a synthetic medium until reaching a stable methane production rate and then switching the reactor over to DPW and allowing acidogenic growth. The start-up period was reduced to 35 days as a result of this operational mode. The reactor was able to handle 8 kg COD/cubic m density after 35 days of operation. (Refs. 24).

  10. A Strong Start-up Scene Flourishes in the Life Sciences Capital Basel.

    PubMed

    Burckhardt, Peter

    2014-12-01

    Basel is known for its successful global players in Pharma, Agro and Chemicals. The wealth of top-tier companies, universities and academic institutions in such a small region is unparalleled. It creates an optimum climate for world-class research and its translation into successful businesses. This is also reflected in a strong start-up scene. Over the past decades the multinational players have shown that they are able to adapt to the ever-increasing challenges in the market. Basel has seen blue-chip company mergers, accompanied by the transfer of business assets into spin-off companies. This process created a mind-set for change which has positively influenced the local start-up environment. Actelion is one of these former spin-offs that successfully made the transition to become a global player. BioVersys and PIQUR are two of the most promising very early stage Swiss biotech companies. Many other examples can be found in Northwestern Switzerland. The region also offers a solid background of supporting activities. Infrastructure, coaching and all other support are offered and complement national innovation initiatives.

  11. Community structure dynamics during startup in microbial fuel cells - The effect of phosphate concentrations.

    PubMed

    Yanuka-Golub, Keren; Reshef, Leah; Rishpon, Judith; Gophna, Uri

    2016-07-01

    For microbial fuel cells (MFCs) to become a cost-effective wastewater treatment technology, they must produce a stable electro-active microbial community quickly and operate under realistic wastewater nutrient conditions. The composition of the anodic-biofilm and planktonic-cells communities was followed temporally for MFCs operated under typical laboratory phosphate concentrations (134mgL(-1)P) versus wastewater phosphate concentrations (16mgL(-1)P). A stable peak voltage was attained two-fold faster in MFCs operating under lower phosphate concentration. All anodic-biofilms were composed of well-known exoelectrogenic bacterial families; however, MFCs showing faster startup and a stable voltage had a Desulfuromonadaceae-dominated-biofilm, while biofilms co-dominated by Desulfuromonadaceae and Geobacteraceae characterized slower or less stable MFCs. Interestingly,planktonic-cell concentrations of these bacteria followed a similar trend as the anodic-biofilm and could therefore serve as a biomarker for its formation. These results demonstrate that wastewater-phosphate concentrations do not compromise MFCs efficiency, and considerably speed up startup times.

  12. A Strong Start-up Scene Flourishes in the Life Sciences Capital Basel.

    PubMed

    Burckhardt, Peter

    2014-12-01

    Basel is known for its successful global players in Pharma, Agro and Chemicals. The wealth of top-tier companies, universities and academic institutions in such a small region is unparalleled. It creates an optimum climate for world-class research and its translation into successful businesses. This is also reflected in a strong start-up scene. Over the past decades the multinational players have shown that they are able to adapt to the ever-increasing challenges in the market. Basel has seen blue-chip company mergers, accompanied by the transfer of business assets into spin-off companies. This process created a mind-set for change which has positively influenced the local start-up environment. Actelion is one of these former spin-offs that successfully made the transition to become a global player. BioVersys and PIQUR are two of the most promising very early stage Swiss biotech companies. Many other examples can be found in Northwestern Switzerland. The region also offers a solid background of supporting activities. Infrastructure, coaching and all other support are offered and complement national innovation initiatives. PMID:26508602

  13. Advanced start-up of anaerobic attached film expanded bed reactor by pre-aeration of biofilm carrier.

    PubMed

    Ye, Fen-xia; Chen, Ying-xu; Feng, Xiao-shan

    2005-01-01

    The start-up and performance of the anaerobic attached film expanded bed (AAFEB) reactor with pre-aeration of carrier were investigated. The carriers of the reactors had been aerated for 10 days before they were put into the AAFEB reactors. The results indicated that the reactors advance the start-up by 15 days, and maintain higher efficiency when they were subjected to organic and hydraulic loading shock, but during steady-state operation, the reactors did not show better performance than the control reactors without pre-aeration of carrier. The thicker biofilm and higher biomass concentration of the reactors with pre-aeration were observed during the start-up period, but the difference between two types of reactors tapered with the time course, and at the steady-state operation, the difference between two types of reactors on these two parameters was not obvious. Maximum specific methane or acids production rates, dehydrogenase activity and coenzyme F(420) content were continuously higher than those of the control reactors. After running 30 days, filamentous bacteria dominated in the reactors with pre-aeration, whereas the cocci were predominant species in the control reactors. It was suggested that the action of the biofilm is strongly dependent on the biofilm thickness or the biomass concentration in normal circumstances, but under adverse circumstances, such as organic or hydraulic loading shock, the characteristics and activity of the anaerobic granular sludge play key roles on the reactor performance. These results clearly indicated that pre-aeration of carrier favor to enhance the start-up and performance of AAFEB reactor. PMID:15364089

  14. Competency-Based Adult Education Sample Activities.

    ERIC Educational Resources Information Center

    Dauzat, Sam V.; Bryant, Nerissa

    For use by adult basic education teachers, this curriculum guide is intended as a frame of reference for building a total instructional program designed around a competency-based and skill-based curriculum. The 104 sample activities are categorized under subheadings of the following topics: Occupational Knowledge, Health, Government and Law,…

  15. Developing an Energy Performance Modeling Startup Kit

    SciTech Connect

    Wood, A.

    2012-10-01

    In 2011, the NAHB Research Center began the first part of the multi-year effort by assessing the needs and motivations of residential remodelers regarding energy performance remodeling. The scope is multifaceted - all perspectives will be sought related to remodeling firms ranging in size from small-scale, sole proprietor to national. This will allow the Research Center to gain a deeper understanding of the remodeling and energy retrofit business and the needs of contractors when offering energy upgrade services. To determine the gaps and the motivation for energy performance remodeling, the NAHB Research Center conducted (1) an initial series of focus groups with remodelers at the 2011 International Builders' Show, (2) a second series of focus groups with remodelers at the NAHB Research Center in conjunction with the NAHB Spring Board meeting in DC, and (3) quantitative market research with remodelers based on the findings from the focus groups. The goal was threefold, to: Understand the current remodeling industry and the role of energy efficiency; Identify the gaps and barriers to adding energy efficiency into remodeling; and Quantify and prioritize the support needs of professional remodelers to increase sales and projects involving improving home energy efficiency. This report outlines all three of these tasks with remodelers.

  16. Rapid and successful start-up of anammox process by immobilizing the minimal quantity of biomass in PVA-SA gel beads.

    PubMed

    Ali, Muhammad; Oshiki, Mamoru; Rathnayake, Lashitha; Ishii, Satoshi; Satoh, Hisashi; Okabe, Satoshi

    2015-08-01

    Rapid start-up of anaerobic ammonium oxidation (anammox) process in up-flow column reactors was successfully achieved by immobilizing minimal quantity of biomass in polyvinyl alcohol (PVA)-sodium alginate (SA) gel beads. The changes in the reactor performance (i.e., nitrogen removal rate; NRR) were monitored with time. The results demonstrate that the reactor containing the immobilized biomass concentration of 0.33 g-VSS L(-1) achieved NRR of 10.8 kg-N m(-3) d(-1) after 35-day operation, whereas the reactor containing the granular biomass of 2.5 g-VSS L(-1) could achieve only NRR of 3.5 kg-N m(-3) d(-1). This indicates that the gel immobilization method requires much lower seeding biomass for start-up of anammox reactor. To explain the better performance of the immobilized biomass, the biological and physicochemical properties of the immobilized biomass were characterized and compared with the naturally aggregated granular biomass. Effective diffusion coefficient (De) in the immobilized biomass was directly determined by microelectrodes and found to be three times higher than one in the granular biomass. High anammox activity (i.e., NH4(+) and NO2(-) consumption rates) was evenly detected throughout the gel beads by microelectrodes due to faster and deeper substrate transport. In contrast, anammox activity was localized in the outer layers of the granular biomass, indicating that the inner biomass could not contribute to the nitrogen removal. This difference was in good agreement with the spatial distribution of microbes analysed by fluorescence in situ hybridization (FISH). Based on these results, PVA-SA gel immobilization is an efficient strategy to initiate anammox reactors with minimal quantity of anammox biomass.

  17. Theoretical proof of edge search strategy applied to power plant start-up scheduling.

    PubMed

    Kamiya, A; Kawai, K; Ono, I; Kobayashi, S

    2002-01-01

    Power plant start-up scheduling is aimed at minimizing the start-up time while limiting maximum turbine rotor stresses. This scheduling problem is highly nonlinear and has a number of local optima. In our previous research, we proposed an efficient search model: genetic algorithms (GAs) with enforcement operation to focus the search along the edge of the feasible space where the optimal schedule is supposed to stay. Based on a nonlinear dynamic simulation and a linear inverse calculation with the iteration method, the enforcement operation is applied to move schedules generated by GA toward the edge. We prove that the optimal schedule lies on the edge, ensuring that searching along the edge instead of the entire space can improve the search efficiency significantly without missing the optimum. Furthermore, we provide a theoretical setting equation for the inverse enforcement gains of the linear inverse calculation, intended to move schedules closer to the edge at each iteration of the enforcement operation. The theoretical setting equation is verified and discussed with the test results. We propose the theoretical setting equation with the test results as a guideline for the use of our proposed search model: GA with enforcement operation.

  18. Activated, coal-based carbon foam

    DOEpatents

    Rogers, Darren Kenneth; Plucinski, Janusz Wladyslaw

    2004-12-21

    An ablation resistant, monolithic, activated, carbon foam produced by the activation of a coal-based carbon foam through the action of carbon dioxide, ozone or some similar oxidative agent that pits and/or partially oxidizes the carbon foam skeleton, thereby significantly increasing its overall surface area and concurrently increasing its filtering ability. Such activated carbon foams are suitable for application in virtually all areas where particulate or gel form activated carbon materials have been used. Such an activated carbon foam can be fabricated, i.e. sawed, machined and otherwise shaped to fit virtually any required filtering location by simple insertion and without the need for handling the "dirty" and friable particulate activated carbon foam materials of the prior art.

  19. Activated, coal-based carbon foam

    SciTech Connect

    Rogers, Darren Kenneth; Plucinski, Janusz Wladyslaw

    2009-06-09

    An ablation resistant, monolithic, activated, carbon foam produced by the activation of a coal-based carbon foam through the action of carbon dioxide, ozone or some similar oxidative agent that pits and/or partially oxidizes the carbon foam skeleton, thereby significantly increasing its overall surface area and concurrently increasing its filtering ability. Such activated carbon foams are suitable for application in virtually all areas where particulate or gel form activated carbon materials have been used. Such an activated carbon foam can be fabricated, i.e. sawed, machined and otherwise shaped to fit virtually any required filtering location by simple insertion and without the need for handling the "dirty" and friable particulate activated carbon foam materials of the prior art.

  20. Internet-Based Physical Activity Interventions

    PubMed Central

    Joseph, Rodney P.; Durant, Nefertiti H.; Benitez, Tanya J.; Pekmezi, Dorothy W.

    2014-01-01

    This article provides a comprehensive review of Internet– and Website–based physical activity interventions targeting adult populations. Search procedures identified 72 unique Internet-based physical activity interventions published in peer-reviewed journals. Participants of the studies were predominately White, middle-aged (mean age = 43.3 years), and female (65.9%). Intervention durations ranged from 2 weeks to 13 months (median = 12 weeks). Forty-six of the studies were randomized controlled trials, 21 were randomized trials without a control condition, 2 were non–randomized controlled trials, and 3 used a single-group design. The majority of studies (n = 68) assessed outcomes immediately following the end of the intervention period, and 16 studies provided delayed postintervention assessments. Forty-four of the 72 studies (61.1%) reported significant increases in physical activity. Future directions for Internet-based physical activity interventions include increasing representation of minority and male populations in Internet-based efforts, conducting delayed postintervention follow-up assessments, and incorporating emerging technologies (ie, cellular and Smartphones) into Internet-based physical activity efforts. PMID:25045343

  1. Tokamak startup: problems and scenarios related to the transient phases of ignited tokamak operations

    SciTech Connect

    Sheffield, J.

    1985-01-01

    During recent years improvements have been made to tokamak startup procedures, which are important to the optimization of ignited tokamaks. The use of rf-assisted startup and noninductive current drive has led to substantial reduction and even complete elimination of the volt-seconds used during startup, relaxing constraints on poloidal coil, vacuum vessel, and structure design. This paper reviews these and other improvements and discusses the various bulk heating techniques that may be used to ignite a D-T plasma.

  2. Activity based video indexing and search

    NASA Astrophysics Data System (ADS)

    Chen, Yang; Jiang, Qin; Medasani, Swarup; Allen, David; Lu, Tsai-ching

    2010-04-01

    We describe a method for searching videos in large video databases based on the activity contents present in the videos. Being able to search videos based on the contents (such as human activities) has many applications such as security, surveillance, and other commercial applications such as on-line video search. Conventional video content-based retrieval (CBR) systems are either feature based or semantics based, with the former trying to model the dynamics video contents using the statistics of image features, and the latter relying on automated scene understanding of the video contents. Neither approach has been successful. Our approach is inspired by the success of visual vocabulary of "Video Google" by Sivic and Zisserman, and the work of Nister and Stewenius who showed that building a visual vocabulary tree can improve the performance in both scalability and retrieval accuracy for 2-D images. We apply visual vocabulary and vocabulary tree approach to spatio-temporal video descriptors for video indexing, and take advantage of the discrimination power of these descriptors as well as the scalability of vocabulary tree for indexing. Furthermore, this approach does not rely on any model-based activity recognition. In fact, training of the vocabulary tree is done off-line using unlabeled data with unsupervised learning. Therefore the approach is widely applicable. Experimental results using standard human activity recognition videos will be presented that demonstrate the feasibility of this approach.

  3. Reducing start-up time and minimizing energy losses of Microbial Fuel Cells using Maximum Power Point Tracking strategy

    NASA Astrophysics Data System (ADS)

    Molognoni, Daniele; Puig, Sebastià; Balaguer, M. Dolors; Liberale, Alessandro; Capodaglio, Andrea G.; Callegari, Arianna; Colprim, Jesús

    2014-12-01

    Microbial Fuel Cells (MFCs) are considered to be an environmental friendly energy conversion technology. The main limitations that delay their industrialization include low current and power densities achievable and long start-up times. Maximum Power Point Tracking (MPPT) has been proposed as a method to enhance MFCs electrical performances. However, the specialized literature is still lacking of experimental works on scaled-up reactors and/or real wastewater utilization. This study evaluates the impact of a MPPT system applied to MFCs treating swine wastewater in terms of start-up time and long-term performance. For this purpose, two replicate cells were compared, one with applied MPPT control and one working with fixed resistance. Both MFCs were continuously fed with swine wastewater to validate the control system under real and dynamic conditions. The study demonstrated that the automatic resistance control was able to reduce the start-up time of about one month. Moreover, MPPT system increased of 40% the Coulombic efficiency at steady-state conditions, reduced energy losses associated with anode and cathode reactions and limited methanogenic activity in the anode chamber. A power density of 5.0 ± 0.2 W m-3 NAC was achieved feeding the system at an organic loading rate of 10 kg COD m-3 d-1.

  4. Bootstrap finance: the art of start-ups.

    PubMed

    Bhide, A

    1992-01-01

    Entrepreneurship is more popular than ever: courses are full, policymakers emphasize new ventures, managers yearn to go off on their own. Would-be founders often misplace their energies, however. Believing in a "big money" model of entrepreneurship, they spend a lot of time trying to attract investors instead of using wits and hustle to get their ideas off the ground. A study of 100 of the 1989 Inc. "500" list of fastest growing U.S. start-ups attests to the value of bootstrapping. In fact, what it takes to start a business often conflicts with what venture capitalists require. Investors prefer solid plans, well-defined markets, and track records. Entrepreneurs are heavy on energy and enthusiasm but may be short on credentials. They thrive in rapidly changing environments where uncertain prospects may scare off established companies. Rolling with the punches is often more important than formal plans. Striving to adhere to investors' criteria can diminish the flexibility--the try-it, fix-it approach--an entrepreneur needs to make a new venture work. Seven principles are basic for successful start-ups: get operational fast; look for quick break-even, cash-generating projects; offer high-value products or services that can sustain direct personal selling; don't try to hire the crack team; keep growth in check; focus on cash; and cultivate banks early. Growth and change are the start-up's natural environment. But change is also the reward for success: just as ventures grow, their founders usually have to take a fresh look at everything again: roles, organization, even the very policies that got the business up and running.

  5. Startup of the FFTF sodium cooled reactor. [Acceptance Test Program

    SciTech Connect

    Redekopp, R.D.; Umek, A.M.

    1981-03-01

    The Fast Flux Test Facility (FFTF), located on the Department of Energy (DOE) Hanford Reservation near Richland, Washington, is a 3 Loop 400 MW(t) sodium cooled fast reactor with a primary mission to test fuels and materials for development of the Liquid Metal Fast Breeder Reactor (LMFBR). Bringing FFTF to a condition to accomplish this mission is the goal of the Acceptance Test Program (ATP). This program was the mechanism for achieving startup of the FFTF. Highlights of the ATP involving the system inerting, liquid metal and inerted cell testing and initial ascent to full power are discussed.

  6. Start-Up of FEL Oscillator from Shot Noise

    SciTech Connect

    Kumar, V.; Krishnagopal, S.; Fawley, W.M.

    2007-01-25

    In free-electron laser (FEL) oscillators, as inself-amplified spontaneous emission (SASE) FELs, the buildup of cavitypower starts from shot noise resulting from the discreteness ofelectronic charge. It is important to do the start-up analysis for thebuild-up of cavity power in order to fix the macropulse width from theelectron accelerator such that the system reaches saturation. In thispaper, we use the time-dependent simulation code GINGER [1]toperformthis analysis. We present results of this analysis for theparameters of the Compact Ultrafast TErahertz FEL (CUTE-FEL) [2]beingbuilt atRRCAT.

  7. Structure-Based Predictions of Activity Cliffs

    PubMed Central

    Husby, Jarmila; Bottegoni, Giovanni; Kufareva, Irina; Abagyan, Ruben; Cavalli, Andrea

    2015-01-01

    In drug discovery, it is generally accepted that neighboring molecules in a given descriptors' space display similar activities. However, even in regions that provide strong predictability, structurally similar molecules can occasionally display large differences in potency. In QSAR jargon, these discontinuities in the activity landscape are known as ‘activity cliffs’. In this study, we assessed the reliability of ligand docking and virtual ligand screening schemes in predicting activity cliffs. We performed our calculations on a diverse, independently collected database of cliff-forming co-crystals. Starting from ideal situations, which allowed us to establish our baseline, we progressively moved toward simulating more realistic scenarios. Ensemble- and template-docking achieved a significant level of accuracy, suggesting that, despite the well-known limitations of empirical scoring schemes, activity cliffs can be accurately predicted by advanced structure-based methods. PMID:25918827

  8. Start-up performance of a full-scale riverbank filtration site regarding removal of DOC, nutrients, and trace organic chemicals.

    PubMed

    Regnery, Julia; Barringer, Jessica; Wing, Alexandre D; Hoppe-Jones, Christiane; Teerlink, Jennifer; Drewes, Jörg E

    2015-05-01

    The performance of a full-scale riverbank filtration facility in Colorado was evaluated from initial start-up over a period of seven years including the impact of seasonal variations to determine whether sustainable attenuation of various chemical constituents could be achieved. Both, annual and seasonal average concentrations were determined for several wastewater-derived constituents including dissolved organic carbon (DOC), ultraviolet absorbance at 254 nm, nitrate, phosphate for the years 2006, 2009, 2010, 2012, and trace organic chemicals (TOrC) for years 2009, 2010, and 2012. ANOVA analyses and Student's t-tests were performed to evaluate the consistency of contaminant attenuation at the site. Findings revealed no significant statistical differences for any of the bulk parameters with the exception of phosphate suggesting a highly reliable attenuation of DOC and nitrate from start-up to full-scale performance. Phosphate attenuation, however, exhibited a steady decline, which was likely attributed to exhaustion of sorption sites in the subsurface porous media. The river's flow regime influenced both occurrence levels and attenuation of TOrC during riverbank filtration, i.e. less river discharge resulted in higher TOrC concentrations and lower proportion of river water in the recovered groundwater. Differences in removal performance between annual data sets for caffeine, trimethoprim, sulfamethoxazole, and carbamazepine were caused by variations in the source; concentrations in riverbank filtrate remained similar over several years. The seasonal assessment for TOrC revealed steady or improving removal between winter and summer seasons based on the statistical analysis with atenolol being the only exception likely due to an increased microbial activity at elevated temperatures. PMID:25679362

  9. DWPF STARTUP FRIT VISCOSITY MEASUREMENT ROUND ROBIN RESULTS

    SciTech Connect

    Crum, Jarrod V.; Edwards, Tommy B.; Russell, Renee L.; Workman, Phyllis J.; Schweiger, Michael J.; Schumacher, Ray F.; Smith, Donald E.; Peeler, David K.; Vienna, John D.

    2012-07-31

    A viscosity standard is needed to replace the National Institute of Standards and Technology (NIST) glasses currently being used to calibrate viscosity measurement equipment. The current NIST glasses are either unavailable or less than ideal for calibrating equipment to measure the viscosity of high-level waste glasses. This report documents the results of a viscosity round robin study conducted on the Defense Waste Processing Facility (DWPF) startup frit. DWPF startup frit was selected because its viscosity-temperature relationship is similar to most DWPF and Hanford high-level waste glass compositions. The glass underwent grinding and blending to homogenize the large (100 lb) batch. Portions of the batch were supplied to the laboratories (named A through H) for viscosity measurements following a specified temperature schedule with a temperature range of 1150 C to 950 C and with an option to measure viscosity at lower temperatures if their equipment was capable of measuring at the higher viscosities. Results were used to fit the Vogel-Tamman-Fulcher and Arrhenius equations to viscosity as a function of temperature for the entire temperature range of 460 C through 1250 C as well as the limited temperature interval of approximately 950 C through 1250 C. The standard errors for confidence and prediction were determined for the fitted models.

  10. Initial Plasma Startup Test on SUNIST Spherical Tokamak

    NASA Astrophysics Data System (ADS)

    Wang, Ying; Zeng, Li; He, Yexi; SUNIST Team

    2003-12-01

    The goal of the Sino-United Spherical Tokamak (SUNIST) at Tsinghua University is to extend the understanding of toroidal plasma physics at a low aspect ratio (R/a approx 1.3) and to demonstrate a maintainable target plasma by non-inductive startup. The SUNIST device is designed to operate with up to 13 kA of ohmic heating field current, and to 0.15 T of toroidal field at 10 kA of discharge current. All of the poloidal fields can provide 30 mVs of Volt-seconds transformer. Experimental results of plasma startup show that SUNIST has remarkable characteristics of high ramp rate (dIP/dt approx 50 MA/s), high normalized current IN of about 2.8 (IN = (IP/aBT), and high-efficiency (IP/IROD approx 0.4) production of plasma current while operating at a low toroidal field. Major disruption phenomena have not been observed from magnetic diagnostics of all testing shots. Initial discharges with 52 kA of plasma current (exceeding the designed value of 50 kA), 2 ms of pulse length and 50 MA/s of ramp rate have been achieved easily with pre-ionized filament.

  11. Start-up analysis for automotive PEM fuel cell systems

    NASA Astrophysics Data System (ADS)

    De Francesco, M.; Arato, E.

    The development of fuel cell cars can play an important role in resolving transport problems, due to the high environmental compatibility and high efficiency of this kind of vehicle. Among the different types of fuel cells, proton-exchange membrane fuel cells (PEMFCs) are considered the best solution for automotive applications at the moment. In this work, constructive criteria are discussed with the aim of obtaining a power generation module adaptable to a wide range of cars. A particular problem in accomplishing the overall project is represented by the definition of the compressor system for air feeding. In this work, the design approach to the problem will be delineated: some options are reviewed and the best solution is analysed. The transient response of the system (fuel cell and compressor) is investigated in order to optimise the start-up running through a model of a fuel cell stack and a compressor simulation. The model and its results are proposed as a work procedure to solve the problem, by varying external conditions: in fact, to perform the system start-up under stable conditions, the air relative humidity and temperature must be maintained in a proper range of values. The approach here presented has been utilised for the definition of the characteristics of the power module and layout of a middle-size hybrid city bus in the framework of a project promoted by the European Union.

  12. Space based astronomy: Teacher's guide with activities

    NASA Technical Reports Server (NTRS)

    Rosenberg, Carla B. (Editor); Weiler, Edward; Morrow, Cherilyn; Bacon, Pamela M.; Thorne, Muriel; Blanchard, Paul A.; Howard, Sethane; Pengra, Patricia R.; Brown, Deborah A.; Winrich, Ralph

    1994-01-01

    This curriculum guide uses hands-on activities to help students and teachers understand the significance of space-based astronomy - astronomical observations made from outer space. The guide contains few of the traditional activities found in many astronomy guides such as constellation studies, lunar phases, and planetary orbits. Instead, it tells the story of why it is important to observe celestial objects from outer space and how to study the entire electromagnetic spectrum. The guide begins with a survey of astronomy related NASA spacecraft. This is followed by a collection of activities in four units: (1) the atmospheric filter; (2) the electromagnetic spectrum; (3) collecting electromagnetic radiation; and (4) down to Earth. A curriculum index identifies the curriculum areas each activity addresses. The guide concludes with a glossary, reference list, a NASA Resources list, and an evaluation card. It is designed for students in grades 5 through 8.

  13. Rodent model of activity-based anorexia.

    PubMed

    Carrera, Olaia; Fraga, Ángela; Pellón, Ricardo; Gutiérrez, Emilio

    2014-04-10

    Activity-based anorexia (ABA) consists of a procedure that involves the simultaneous exposure of animals to a restricted feeding schedule, while free access is allowed to an activity wheel. Under these conditions, animals show a progressive increase in wheel running, a reduced efficiency in food intake to compensate for their increased activity, and a severe progression of weight loss. Due to the parallelism with the clinical manifestations of anorexia nervosa including increased activity, reduced food intake and severe weight loss, the ABA procedure has been proposed as the best analog of human anorexia nervosa (AN). Thus, ABA research could both allow a better understanding of the mechanisms underlying AN and generate useful leads for treatment development in AN.

  14. Numerical Simulation of Non-Inductive Startup of the Pegasus Toroidal Experiment

    NASA Astrophysics Data System (ADS)

    O'Bryan, John B.

    both sets of calculations. Synthetic Mirnov coils at the locations used in the experiment observe magnetic fluctuation amplitudes of order 5 % and significant activity in the 10-20 kHz range in agreement with experimental measurements. Based on the cross-power spectrograms, the two-fluid calculation more accurately reproduces the frequency response of the experimental dynamics.

  15. DNA-based control of protein activity

    PubMed Central

    Engelen, W.; Janssen, B. M. G.

    2016-01-01

    DNA has emerged as a highly versatile construction material for nanometer-sized structures and sophisticated molecular machines and circuits. The successful application of nucleic acid based systems greatly relies on their ability to autonomously sense and act on their environment. In this feature article, the development of DNA-based strategies to dynamically control protein activity via oligonucleotide triggers is discussed. Depending on the desired application, protein activity can be controlled by directly conjugating them to an oligonucleotide handle, or expressing them as a fusion protein with DNA binding motifs. To control proteins without modifying them chemically or genetically, multivalent ligands and aptamers that reversibly inhibit their function provide valuable tools to regulate proteins in a noncovalent manner. The goal of this feature article is to give an overview of strategies developed to control protein activity via oligonucleotide-based triggers, as well as hurdles yet to be taken to obtain fully autonomous systems that interrogate, process and act on their environments by means of DNA-based protein control. PMID:26812623

  16. MEMS startups: disruptive technology and business do's and don'ts

    NASA Astrophysics Data System (ADS)

    Bryzek, Janusz

    2005-02-01

    This paper characterizes factors that affect the probability of success for new startups. These guidelines are derived primarily from Venture Capital industry experience in funding disruptive technology companies. It follows with an overview of Silicon Valley MEMS and MOEMS startups and provides with a summary of Do"s and Don"ts for entrepreneurs.

  17. Manual of Considerations and Techniques for Start-Up of Municipal Wastewater Treatment Facilities.

    ERIC Educational Resources Information Center

    Rader, R. D.; And Others

    This manual provides guidance for putting into initial operation a new municipal wastewater treatment plant, a new addition to an existing treatment plant, or a change in the mode of a treatment plant's operation. Information is provided on preparing for actual treatment plant start-up. Preparation for start-up includes: staffing the plant,…

  18. Leadership toward Creativity in Virtual Work in a Start-Up Context

    ERIC Educational Resources Information Center

    Humala, Iris Annukka

    2015-01-01

    Purpose: This paper aims to better understand how to lead toward creativity in virtual work in a start-up context. Design/methodology/approach: The study investigates the participants' experiences about the learning challenges in leadership toward creativity in virtual work in a start-up company and the meanings attributed to their experiences,…

  19. Going Boldly Into the Future: Skills and Australian High Technology Start-Up Firms.

    ERIC Educational Resources Information Center

    Whittingham, Karen

    The skill needs of Australian high-technology start-up companies and the implications of those skill needs for vocational education and training (VET) were examined through a study of 14 start-ups' inherent abilities to access the VET system and on VET's relevance to their needs. The case studies documented a strong demand and role for VET in the…

  20. Navigating the Interface between Design Education and Fashion Business Start-up

    ERIC Educational Resources Information Center

    Mills, Colleen E.

    2012-01-01

    Purpose: The purpose of this paper is to address the interface between design education and business start-up in the designer fashion industry (DFI) and provide a new framework for reflecting on ways to improve design education and graduates' business start-up preparedness. Design/methodology/approach: This interpretive study employed…

  1. 26 CFR 1.195-1 - Election to amortize start-up expenditures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Election to amortize start-up expenditures. 1.195-1 Section 1.195-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED....195-1 Election to amortize start-up expenditures. For further guidance, see § 1.195-1T....

  2. 48 CFR 1631.205-77 - FEHBP start-up and other nonrecurring costs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false FEHBP start-up and other nonrecurring costs. 1631.205-77 Section 1631.205-77 Federal Acquisition Regulations System OFFICE OF PERSONNEL... COST PRINCIPLES AND PROCEDURES Contracts With Commercial Organizations 1631.205-77 FEHBP start-up...

  3. 26 CFR 1.195-1 - Election to amortize start-up expenditures.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 3 2011-04-01 2011-04-01 false Election to amortize start-up expenditures. 1.195-1 Section 1.195-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED... (continued) § 1.195-1 Election to amortize start-up expenditures. For further guidance, see § 1.195-1T....

  4. 48 CFR 1631.205-77 - FEHBP start-up and other nonrecurring costs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false FEHBP start-up and other nonrecurring costs. 1631.205-77 Section 1631.205-77 Federal Acquisition Regulations System OFFICE OF PERSONNEL... COST PRINCIPLES AND PROCEDURES Contracts With Commercial Organizations 1631.205-77 FEHBP start-up...

  5. 76 FR 56973 - Elections Regarding Start-Up Expenditures, Corporation Organizational Expenditures, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... Wednesday, August 17, 2011 (76 FR 50887) relating to elections to deduct start-up expenditures... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Internal Revenue Service 26 CFR Part 1 RIN 1545-BE77 Elections Regarding Start-Up Expenditures,...

  6. 48 CFR 1631.205-77 - FEHBP start-up and other nonrecurring costs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false FEHBP start-up and other nonrecurring costs. 1631.205-77 Section 1631.205-77 Federal Acquisition Regulations System OFFICE OF PERSONNEL... COST PRINCIPLES AND PROCEDURES Contracts With Commercial Organizations 1631.205-77 FEHBP start-up...

  7. 48 CFR 1631.205-77 - FEHBP start-up and other nonrecurring costs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false FEHBP start-up and other nonrecurring costs. 1631.205-77 Section 1631.205-77 Federal Acquisition Regulations System OFFICE OF PERSONNEL... COST PRINCIPLES AND PROCEDURES Contracts With Commercial Organizations 1631.205-77 FEHBP start-up...

  8. 26 CFR 1.195-1T - Election to amortize start-up expenditures (temporary).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... prior to that date (§ 1.195-1 as contained in 26 CFR part 1 edition revised as of April 1, 2008). (e... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Election to amortize start-up expenditures... (continued) § 1.195-1T Election to amortize start-up expenditures (temporary). (a) In general. Under...

  9. 48 CFR 1631.205-77 - FEHBP start-up and other nonrecurring costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true FEHBP start-up and other nonrecurring costs. 1631.205-77 Section 1631.205-77 Federal Acquisition Regulations System OFFICE OF PERSONNEL... COST PRINCIPLES AND PROCEDURES Contracts With Commercial Organizations 1631.205-77 FEHBP start-up...

  10. Resourcing Lab Experiments for New Ventures: The Potential of a Start-Up Database

    ERIC Educational Resources Information Center

    Pietrobon, Alberto

    2009-01-01

    This article responds to "Laboratory experiments as a tool in the empirical economic analysis of high-expectation start-ups" by Martin Curley and Piero Formica, published in the December 2008 issue of "Industry and Higher Education". Curley and Formica introduce a new concept for high-expectation start-ups, involving the use of "laboratory…

  11. Environmental risk assessment for start-up of a new consolidated maintenance facility

    SciTech Connect

    Heubach, J.G.; Wise, J.A.

    1992-10-01

    This paper summarizes a case study of a risk assessment for a consolidated maintenance facility (CMF). An interdisciplinary team was formed to identify and evaluate showstopper'' risks which could delay or prevent ontime, safe, and economical operation of a CMF and to recommend ways to mitigate the risks. The risk assessment was constrained by time, information, incomplete plans and facilities, and a concomitant major transition in manufacturing process, organization, and technology. Working within these constraints, the team integrated convergent findings into estimates of high, medium, and low risks based on the subjective likelihood of occurrence and predicted consequences of potential hazard events. The team also made risk-reduction recommendations for facility detail design and production start-up. The findings and recommendations reported in this study focus on risks related to environmental design and workstation ergonomics. Findings from the risk assessment effort should aid other constrained risk assessments and applied research on similar facilities.

  12. Plant-based active photoprotectants for sunscreens.

    PubMed

    Cefali, L C; Ataide, J A; Moriel, P; Foglio, M A; Mazzola, P G

    2016-08-01

    Excessive exposure to the sun's radiation is the major exogenous mediator of skin damage, which accelerates skin ageing and increases the risk of developing skin cancer. Compounds with photoprotectant activity are extremely useful for decreasing the effect of ultraviolet (UV) radiation on the skin; however, numerous sun filters, especially organic sunscreens, are allergenic. Therefore, the development of formulations containing plant extracts, which may be potentially safer, is extensively being explored. Plant-based cosmetics are commonly used to avoid skin ageing because they contain antioxidant agents that minimize free radical activity, and numerous studies have investigated the skin-protectant effects of related plant species. In addition to their antioxidant properties, plant-based cosmetics protect the skin against solar radiation because they contain polyphenols such as flavonoids and carotenoids. Therefore, this study aims to present a review of plant species commonly used in sunscreens to protect the skin against damage due to sunlight exposure. PMID:26919163

  13. Paper-Based Active Tactile Sensor Array.

    PubMed

    Zhong, Qize; Zhong, Junwen; Cheng, Xiaofeng; Yao, Xu; Wang, Bo; Li, Wenbo; Wu, Nan; Liu, Kang; Hu, Bin; Zhou, Jun

    2015-11-25

    A paper-based active tactile sensor -array (PATSA) with a dynamic sensitivity of 0.35 V N(-1) is demonstrated. The pixel position of the PATSA can be routed by analyzing the real-time recording voltages in the pressing process. The PATSA performance, which remains functional when removing partial areas, reveals that the device has a potential application to customized electronic skins. PMID:26450138

  14. Lunar base activities and the lunar environment

    NASA Astrophysics Data System (ADS)

    Vondrak, Richard R.

    1992-09-01

    The Moon is an attractive site for astronomical observatories and other facilities because of the absence of a substantial lunar atmosphere and the stability of the lunar surface. The present lunar atmosphere is sufficiently transparent that there is no significant image distortion due to absorption or refraction. This thin atmosphere results from a combination of small sources and prompt losses. The major source that has been identified is the solar wind, whose total mass input into the lunar atmosphere is approximately 50 gm/sec. The major components of the solar wind are light elements (H and He) that promptly escape from the lunar surface by exospheric evaporation (Jeans' escape). The principal atmospheric loss mechanism for heavier gases is photoionization within a period of weeks to months, followed by immediate loss to the solar wind. Lunar base activities will modify the lunar atmosphere if gas is released at a larger rate than that now occurring naturally. Possible gas sources are rocket exhaust, processing of lunar materials, venting of pressurized volumes, and astronaut life support systems. For even modest lunar base activity, such sources will substantially exceed natural sources, although effects are expected to be localized and transient. The Apollo database serves as a useful reference for both measurements of the natural lunar environment and its modification by lunar base activities.

  15. Lunar base activities and the lunar environment

    NASA Technical Reports Server (NTRS)

    Vondrak, Richard R.

    1992-01-01

    The Moon is an attractive site for astronomical observatories and other facilities because of the absence of a substantial lunar atmosphere and the stability of the lunar surface. The present lunar atmosphere is sufficiently transparent that there is no significant image distortion due to absorption or refraction. This thin atmosphere results from a combination of small sources and prompt losses. The major source that has been identified is the solar wind, whose total mass input into the lunar atmosphere is approximately 50 gm/sec. The major components of the solar wind are light elements (H and He) that promptly escape from the lunar surface by exospheric evaporation (Jeans' escape). The principal atmospheric loss mechanism for heavier gases is photoionization within a period of weeks to months, followed by immediate loss to the solar wind. Lunar base activities will modify the lunar atmosphere if gas is released at a larger rate than that now occurring naturally. Possible gas sources are rocket exhaust, processing of lunar materials, venting of pressurized volumes, and astronaut life support systems. For even modest lunar base activity, such sources will substantially exceed natural sources, although effects are expected to be localized and transient. The Apollo database serves as a useful reference for both measurements of the natural lunar environment and its modification by lunar base activities.

  16. Active Geodesics: Region-based Active Contour Segmentation with a Global Edge-based Constraint.

    PubMed

    Appia, Vikram; Yezzi, Anthony

    2011-11-01

    We present an active geodesic contour model in which we constrain the evolving active contour to be a geodesic with respect to a weighted edge-based energy through its entire evolution rather than just at its final state (as in the traditional geodesic active contour models). Since the contour is always a geodesic throughout the evolution, we automatically get local optimality with respect to an edge fitting criterion. This enables us to construct a purely region-based energy minimization model without having to devise arbitrary weights in the combination of our energy function to balance edge-based terms with the region-based terms. We show that this novel approach of combining edge information as the geodesic constraint in optimizing a purely region-based energy yields a new class of active contours which exhibit both local and global behaviors that are naturally responsive to intuitive types of user interaction. We also show the relationship of this new class of globally constrained active contours with traditional minimal path methods, which seek global minimizers of purely edge-based energies without incorporating region-based criteria. Finally, we present some numerical examples to illustrate the benefits of this approach over traditional active contour models.

  17. [Start-up of full-scale UASB reactors].

    PubMed

    Wu, J; Sheng, F; Lu, Z

    2001-09-01

    The UASB reactors treating high-temperature citric acid wastewater could be started up in the alternation of mesophilic and thermophilic ranges because the local climate changed greatly by seasons. The reactors were started up in mesophilic range, and the total efficiency of the two-stage reactors reached 77%-86%; when the temperature of reactors reached 44 degrees C-45 degrees C, the reactors were operated in thermophilic range, and the total efficiency of the two-stage reactors reached 84%-93%; the reactors were re-operated in mesophilic range after closing about 38 days, and the total efficiency of the two-stage reactors reached 82%-96%. The start-up in the alternation of mesophilic and thermophilic ranges of the full-scale UASB reactors and the characteristics of mesophilic and thermophilic granular sludge were reported in this paper.

  18. Dual-Fuel Truck Fleet: Start-Up Experience

    SciTech Connect

    NREL

    1998-09-30

    Although dual-fuel engine technology has been in development and limited use for several years, it has only recently moved toward full-scale operational capability for heavy-duty truck applications. Unlike a bifuel engine, which has two separate fuel systems that are used one at a time, a dual-fuel engine uses two fuel systems simultaneously. One of California's South Coast Air Quality Management District (SCAQMD) current programs is a demonstration of dual-fuel engine technology in heavy-duty trucks. These trucks are being studied as part of the National Renewable Energy Laboratory's (NREL's) Alternative Fuel Truck Program. This report describes the start-up experience from the program.

  19. Defense Waste Processing Facility (DWPF) startup test program: Glass characterization

    SciTech Connect

    Jantzen, C.M.

    1992-07-01

    Liquid high-level nuclear waste will be immobilized at the Savannah River Site (SRS) by vitrification in borosilicate glass. The glass will be processed in the Defense Waste Processing Facility (DWPF) and poured into stainless steel canisters for eventual geologic disposal. Six simulated glass compositions will be processed in the DWPF during initial startup. The glass in 86 of the first 106 full sized canisters will be sampled and characterized. Extensive glass characterization will determine the following: (1) sampling frequency for radioactive operation, (2) verification of the compositionally dependent process-product models, (3) verification of melter mixing, (4) representativeness of the glass from the canister throat sampler, and (5) homogeneity of the canister glass.

  20. Defense Waste Processing Facility (DWPF) startup test program: Glass characterization

    SciTech Connect

    Jantzen, C.M.

    1992-01-01

    Liquid high-level nuclear waste will be immobilized at the Savannah River Site (SRS) by vitrification in borosilicate glass. The glass will be processed in the Defense Waste Processing Facility (DWPF) and poured into stainless steel canisters for eventual geologic disposal. Six simulated glass compositions will be processed in the DWPF during initial startup. The glass in 86 of the first 106 full sized canisters will be sampled and characterized. Extensive glass characterization will determine the following: (1) sampling frequency for radioactive operation, (2) verification of the compositionally dependent process-product models, (3) verification of melter mixing, (4) representativeness of the glass from the canister throat sampler, and (5) homogeneity of the canister glass.

  1. Proceedings: PWR Primary Startup/Shutdown Chemistry Workshop

    SciTech Connect

    2000-08-01

    This workshop summary outlines the proceedings of the EPRI-sponsored PWR Primary Startup/Shutdown Workshop held in San Antonio, Texas on April 25-27, 2000 to support the next revision of current EPRI PWR Chemistry Guidelines. Information was exchanged to assess the effectiveness of the guidelines. The workshop also helped identify issues needing further study before the next revision. Approximately 50 utility and industry representatives attended the workshop with utility personnel chairing four sessions. The workshop provided an opportunity for utility representatives to express an opinion as to the effectiveness of the existing PWR Primary Water Chemistry Guidelines: Volume 2, Revision 4. Potential improvements and additions to the Guidelines are outlined in this report.

  2. The application of neural networks to the SSME startup transient

    NASA Technical Reports Server (NTRS)

    Meyer, Claudia M.; Maul, William A.

    1991-01-01

    Feedforward neural networks were used to model three parameters during the Space Shuttle Main Engine startup transient. The three parameters were the main combustion chamber pressure, a controlled parameter, the high pressure oxidizer turbine discharge temperature, a redlined parameter, and the high pressure fuel pump discharge pressure, a failure-indicating performance parameter. Network inputs consisted of time windows of data from engine measurements that correlated highly to the modeled parameter. A standard backpropagation algorithm was used to train the feedforward networks on two nominal firings. Each trained network was validated with four additional nominal firings. For all three parameters, the neural networks were able to accurately predict the data in the validation sets as well as the training set.

  3. TFTR Mirnov coil analysis at plasma start-up

    SciTech Connect

    Harley, T.R.; Buchenauer, D.A.; Coonrod, J.; McGuire, K.M.

    1986-01-01

    The methods for finding poloidal and toroidal numbers of MHD oscillations from Mirnov coils are reviewed and modified. Examples of various MHD phenomena occurring during start-up on TFTR are illustrated. It is found that the MHD mode structure best fits a model with the toroidal correction included. A new algorithm which finds m,n numbers can accommodate toroidal effects which are manifested in the phase data. The algorithm can find m,n numbers with a given toroidal correction parameter lambda', (lambda' = 0 cylindrical). This algorithm is also used to find the optimal value of lambda' automatically, eliminating the need for ''guesswork.'' The algorithm finds the best parameters to the fit much faster than more conventional computational techniques. 9 refs., 21 figs., 2 tabs.

  4. Activity cliffs and activity cliff generators based on chemotype-related activity landscapes.

    PubMed

    Pérez-Villanueva, Jaime; Méndez-Lucio, Oscar; Soria-Arteche, Olivia; Medina-Franco, José L

    2015-11-01

    Activity cliffs have large impact in drug discovery; therefore, their detection and quantification are of major importance. This work introduces the metric activity cliff enrichment factor and expands the previously reported activity cliff generator concept by adding chemotype information to representations of the activity landscape. To exemplify these concepts, three molecular databases with multiple biological activities were characterized. Compounds in each database were grouped into chemotype classes. Then, pairwise comparisons of structure similarities and activity differences were calculated for each compound and used to construct chemotype-based structure-activity similarity (SAS) maps. Different landscape distributions among four major regions of the SAS maps were observed for different subsets of molecules grouped in chemotypes. Based on this observation, the activity cliff enrichment factor was calculated to numerically detect chemotypes enriched in activity cliffs. Several chemotype classes were detected having major proportion of activity cliffs than the entire database. In addition, some chemotype classes comprising compounds with smooth structure activity relationships (SAR) were detected. Finally, the activity cliff generator concept was applied to compounds grouped in chemotypes to extract valuable SAR information.

  5. Antimicrobial Activity of Carbon-Based Nanoparticles

    PubMed Central

    Maleki Dizaj, Solmaz; Mennati, Afsaneh; Jafari, Samira; Khezri, Khadejeh; Adibkia, Khosro

    2015-01-01

    Due to the vast and inappropriate use of the antibiotics, microorganisms have begun to develop resistance to the commonly used antimicrobial agents. So therefore, development of the new and effective antimicrobial agents seems to be necessary. According to some recent reports, carbon-based nanomaterials such as fullerenes, carbon nanotubes (CNTs) (especially single-walled carbon nanotubes (SWCNTs)) and graphene oxide (GO) nanoparticles show potent antimicrobial properties. In present review, we have briefly summarized the antimicrobial activity of carbon-based nanoparticles together with their mechanism of action. Reviewed literature show that the size of carbon nanoparticles plays an important role in the inactivation of the microorganisms. As major mechanism, direct contact of microorganisms with carbon nanostructures seriously affects their cellular membrane integrity, metabolic processes and morphology. The antimicrobial activity of carbon-based nanostructures may interestingly be investigated in the near future owing to their high surface/volume ratio, large inner volume and other unique chemical and physical properties. In addition, application of functionalized carbon nanomaterials as carriers for the ordinary antibiotics possibly will decrease the associated resistance, enhance their bioavailability and provide their targeted delivery. PMID:25789215

  6. Human body contour data based activity recognition.

    PubMed

    Myagmarbayar, Nergui; Yuki, Yoshida; Imamoglu, Nevrez; Gonzalez, Jose; Otake, Mihoko; Yu, Wenwei

    2013-01-01

    This research work is aimed to develop autonomous bio-monitoring mobile robots, which are capable of tracking and measuring patients' motions, recognizing the patients' behavior based on observation data, and providing calling for medical personnel in emergency situations in home environment. The robots to be developed will bring about cost-effective, safe and easier at-home rehabilitation to most motor-function impaired patients (MIPs). In our previous research, a full framework was established towards this research goal. In this research, we aimed at improving the human activity recognition by using contour data of the tracked human subject extracted from the depth images as the signal source, instead of the lower limb joint angle data used in the previous research, which are more likely to be affected by the motion of the robot and human subjects. Several geometric parameters, such as, the ratio of height to weight of the tracked human subject, and distance (pixels) between centroid points of upper and lower parts of human body, were calculated from the contour data, and used as the features for the activity recognition. A Hidden Markov Model (HMM) is employed to classify different human activities from the features. Experimental results showed that the human activity recognition could be achieved with a high correct rate. PMID:24111015

  7. Human body contour data based activity recognition.

    PubMed

    Myagmarbayar, Nergui; Yuki, Yoshida; Imamoglu, Nevrez; Gonzalez, Jose; Otake, Mihoko; Yu, Wenwei

    2013-01-01

    This research work is aimed to develop autonomous bio-monitoring mobile robots, which are capable of tracking and measuring patients' motions, recognizing the patients' behavior based on observation data, and providing calling for medical personnel in emergency situations in home environment. The robots to be developed will bring about cost-effective, safe and easier at-home rehabilitation to most motor-function impaired patients (MIPs). In our previous research, a full framework was established towards this research goal. In this research, we aimed at improving the human activity recognition by using contour data of the tracked human subject extracted from the depth images as the signal source, instead of the lower limb joint angle data used in the previous research, which are more likely to be affected by the motion of the robot and human subjects. Several geometric parameters, such as, the ratio of height to weight of the tracked human subject, and distance (pixels) between centroid points of upper and lower parts of human body, were calculated from the contour data, and used as the features for the activity recognition. A Hidden Markov Model (HMM) is employed to classify different human activities from the features. Experimental results showed that the human activity recognition could be achieved with a high correct rate.

  8. Activity-Based Protein Profiling of Microbes

    SciTech Connect

    Sadler, Natalie C.; Wright, Aaron T.

    2015-02-01

    Activity-Based Protein Profiling (ABPP) in conjunction with multimodal characterization techniques has yielded impactful findings in microbiology, particularly in pathogen, bioenergy, drug discovery, and environmental research. Using small molecule chemical probes that react irreversibly with specific proteins or protein families in complex systems has provided insights in enzyme functions in central metabolic pathways, drug-protein interactions, and regulatory protein redox, for systems ranging from photoautotrophic cyanobacteria to mycobacteria, and combining live cell or cell extract ABPP with proteomics, molecular biology, modeling, and other techniques has greatly expanded our understanding of these systems. New opportunities for application of ABPP to microbial systems include: enhancing protein annotation, characterizing protein activities in myriad environments, and reveal signal transduction and regulatory mechanisms in microbial systems.

  9. Active-imaging-based underwater navigation

    NASA Astrophysics Data System (ADS)

    Monnin, David; Schmitt, Gwenaël.; Fischer, Colin; Laurenzis, Martin; Christnacher, Frank

    2015-10-01

    Global navigation satellite systems (GNSS) are widely used for the localization and the navigation of unmanned and remotely operated vehicles (ROV). In contrast to ground or aerial vehicles, GNSS cannot be employed for autonomous underwater vehicles (AUV) without the use of a communication link to the water surface, since satellite signals cannot be received underwater. However, underwater autonomous navigation is still possible using self-localization methods which determines the relative location of an AUV with respect to a reference location using inertial measurement units (IMU), depth sensors and even sometimes radar or sonar imaging. As an alternative or a complementary solution to common underwater reckoning techniques, we present the first results of a feasibility study of an active-imaging-based localization method which uses a range-gated active-imaging system and can yield radiometric and odometric information even in turbid water.

  10. Active microring based tunable optical power splitters

    NASA Astrophysics Data System (ADS)

    Peter, Eldhose; Thomas, Arun; Dhawan, Anuj; Sarangi, Smruti R.

    2016-01-01

    In this paper we propose a set of novel tunable optical power splitters based on active microring resonators. They work by operating ring resonators in the transient zone between full resonance and off-resonance states for a specific wavelength. We can achieve different split ratios by either varying the bias voltage, or by selectively enabling a given resonator with a specific split ratio among an array of ring resonators. We take 500 ps to tune the resonator, which is at least 10× better that competing designs. Its split ratio varies from 0.4 to 1.8 for an applied voltage range of 0-5 V.

  11. Characteristics of dioxin emissions at startup and shutdown of MSW incinerators.

    PubMed

    Tejima, Hajime; Nishigaki, Masahide; Fujita, Yasuyuki; Matsumoto, Akihiro; Takeda, Nobuo; Takaoka, Masaki

    2007-01-01

    Dioxin concentrations from municipal waste incinerators in Japan and elsewhere often show low concentrations that comply with legal limits (in this paper, the term "dioxin" designates WHO-TEQ: PCDD/Fs+dioxin-like PCB). However, such data is usually generated under normal steady state operational conditions, and there has been little investigation of releases occurring during startup and shutdown. It is important, therefore, to ascertain quantitatively emissions in an unsteady state (startup and shutdown) in order to correctly evaluate the relationship between emissions from a facility and the surrounding environment. The present study aimed to examine dioxin emissions of a continuously operated incinerator at startup and shutdown, and estimating the time period of greatest emission, and the processes causing dioxin generation. The startup process was divided into five stages and the shutdown into two; at each stage, dioxins in the flue gas were measured at the boiler outlet and the stack. From the concentration of dioxins and the flue gas volume at each stage, the amount of dioxins at startup and shutdown were calculated, and these were compared with that under steady state conditions. Dioxin concentration at the stack under steady state conditions was a very low level, while those at startup and shutdown were higher. In the case where dioxin concentration under a steady state is a low level like in this study, it is indicated that the total annual dioxin emission from a facility could be attributed to the startup periods.

  12. Time-driven activity-based costing.

    PubMed

    Kaplan, Robert S; Anderson, Steven R

    2004-11-01

    In the classroom, activity-based costing (ABC) looks like a great way to manage a company's limited resources. But executives who have tried to implement ABC in their organizations on any significant scale have often abandoned the attempt in the face of rising costs and employee irritation. They should try again, because a new approach sidesteps the difficulties associated with large-scale ABC implementation. In the revised model, managers estimate the resource demands imposed by each transaction, product, or customer, rather than relying on time-consuming and costly employee surveys. This method is simpler since it requires, for each group of resources, estimates of only two parameters: how much it costs per time unit to supply resources to the business's activities (the total overhead expenditure of a department divided by the total number of minutes of employee time available) and how much time it takes to carry out one unit of each kind of activity (as estimated or observed by the manager). This approach also overcomes a serious technical problem associated with employee surveys: the fact that, when asked to estimate time spent on activities, employees invariably report percentages that add up to 100. Under the new system, managers take into account time that is idle or unused. Armed with the data, managers then construct time equations, a new feature that enables the model to reflect the complexity of real-world operations by showing how specific order, customer, and activity characteristics cause processing times to vary. This Tool Kit uses concrete examples to demonstrate how managers can obtain meaningful cost and profitability information, quickly and inexpensively. Rather than endlessly updating and maintaining ABC data,they can now spend their time addressing the deficiencies the model reveals: inefficient processes, unprofitable products and customers, and excess capacity.

  13. Time-driven activity-based costing.

    PubMed

    Kaplan, Robert S; Anderson, Steven R

    2004-11-01

    In the classroom, activity-based costing (ABC) looks like a great way to manage a company's limited resources. But executives who have tried to implement ABC in their organizations on any significant scale have often abandoned the attempt in the face of rising costs and employee irritation. They should try again, because a new approach sidesteps the difficulties associated with large-scale ABC implementation. In the revised model, managers estimate the resource demands imposed by each transaction, product, or customer, rather than relying on time-consuming and costly employee surveys. This method is simpler since it requires, for each group of resources, estimates of only two parameters: how much it costs per time unit to supply resources to the business's activities (the total overhead expenditure of a department divided by the total number of minutes of employee time available) and how much time it takes to carry out one unit of each kind of activity (as estimated or observed by the manager). This approach also overcomes a serious technical problem associated with employee surveys: the fact that, when asked to estimate time spent on activities, employees invariably report percentages that add up to 100. Under the new system, managers take into account time that is idle or unused. Armed with the data, managers then construct time equations, a new feature that enables the model to reflect the complexity of real-world operations by showing how specific order, customer, and activity characteristics cause processing times to vary. This Tool Kit uses concrete examples to demonstrate how managers can obtain meaningful cost and profitability information, quickly and inexpensively. Rather than endlessly updating and maintaining ABC data,they can now spend their time addressing the deficiencies the model reveals: inefficient processes, unprofitable products and customers, and excess capacity. PMID:15559451

  14. Structure-Activity Relationship of Azaindole-Based Glucokinase Activators.

    PubMed

    Paczal, Attila; Bálint, Balázs; Wéber, Csaba; Szabó, Zoltán B; Ondi, Levente; Theret, Isabelle; De Ceuninck, Frédéric; Bernard, Catherine; Ktorza, Alain; Perron-Sierra, Francoise; Kotschy, András

    2016-01-28

    7-Azaindole has been identified as a novel bidentate anchor point for allosteric glucokinase activators. A systematic investigation around three principal parts of the new small molecule glucokinase activators led to a robust SAR in agreement with structural data that also helped to assess the conformational flexibility of the allosteric activation site. The increase in glucose uptake resulting from glucokinase activation in hepatocytes in vitro translated into the efficient lowering of glucose levels in vivo with the best compounds. PMID:26685731

  15. Chromosome positioning from activity-based segregation.

    PubMed

    Ganai, Nirmalendu; Sengupta, Surajit; Menon, Gautam I

    2014-04-01

    Chromosomes within eukaryotic cell nuclei at interphase are not positioned at random, since gene-rich chromosomes are predominantly found towards the interior of the cell nucleus across a number of cell types. The physical mechanisms that could drive and maintain the spatial segregation of chromosomes based on gene density are unknown. Here, we identify a mechanism for such segregation, showing that the territorial organization of chromosomes, another central feature of nuclear organization, emerges naturally from our model. Our computer simulations indicate that gene density-dependent radial segregation of chromosomes arises as a robust consequence of differences in non-equilibrium activity across chromosomes. Arguing that such differences originate in the inhomogeneous distribution of ATP-dependent chromatin remodeling and transcription machinery on each chromosome, we show that a variety of non-random positional distributions emerge through the interplay of such activity, nuclear shape and specific interactions of chromosomes with the nuclear envelope. Results from our model are in reasonable agreement with experimental data and we make a number of predictions that can be tested in experiments. PMID:24459132

  16. Cool-down and frozen start-up behavior of a grooved water heat pipe

    NASA Technical Reports Server (NTRS)

    Jang, Jong Hoon

    1990-01-01

    A grooved water heat pipe was tested to study its characteristics during the cool-down and start-up periods. The water heat pipe was cooled down from the ambient temperature to below the freezing temperature of water. During the cool-down, isothermal conditions were maintained at the evaporator and adiabatic sections until the working fluid was frozen. When water was frozen along the entire heat pipe, the heat pipe was rendered inactive. The start-up of the heat pipe from this state was studied under several different operating conditions. The results show the existence of large temperature gradients between the evaporator and the condenser, and the moving of the melting front of the working fluid along the heat pipe. Successful start-up was achieved for some test cases using partial gravity assist. The start-up behavior depended largely on the operating conditions.

  17. Legal Challenges and Pitfalls for Start-up Companies - 48 Common Questions and Answers.

    PubMed

    Staehelin, Matthias

    2014-12-01

    Transforming a business idea into reality requires a legal implementation plan. The following 48 questions and answers address key issues that typically arise in start-up situations. Early planning can help avoid costly mistakes. PMID:26508601

  18. 40 CFR 60.2195 - What information must I submit prior to initial startup?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Performance for Commercial and Industrial Solid Waste Incineration Units for Which Construction Is Commenced... startup. (a) The type(s) of waste to be burned. (b) The maximum design waste burning capacity. (c)...

  19. 40 CFR 60.2195 - What information must I submit prior to initial startup?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Performance for Commercial and Industrial Solid Waste Incineration Units for Which Construction Is Commenced... startup. (a) The type(s) of waste to be burned. (b) The maximum design waste burning capacity. (c)...

  20. Transient analysis and startup simulation of a thermionic space nuclear reactor system

    SciTech Connect

    El-Genk, M.S.; Xue, Huimin; Paramonov, D. . Dept. of Chemical and Nuclear Engineering)

    1994-01-01

    The thermionic transient analysis model is used to simulate the startup of the TOPAZ-2 space nuclear power system in orbit. The simulated startup procedures are assumed for the purpose of demonstrating the capabilities of the model and may not represent an accurate account of the actual startup procedures of the TOPAZ-2 system. The temperature reactivity feedback effects of the moderator, UO[sub 2] fuel, electrodes, coolant, and other components in the core are calculated, and their effects on the thermal and criticality conditions of the reactor are investigated. Also, estimates of the time constants of the temperature reactivity feedback for the UO[sub 2] fuel and the ZrH moderator during startup, as well as of the total temperature reactivity feedback as a function of the reactor steady-state thermal power, are obtained.

  1. Start-up simulation of a thermionic space nuclear reactor system

    SciTech Connect

    El-Genk, M.S.; Xue, H.; Paramonov, D. )

    1993-01-15

    The Thermionic Transient Analysis Model (TITAM) is used in this paper to simulate the start-up of the TOPAZ-II space nuclear power system in orbit. The start-up procedures simulated herein are assumed for the purpose of demonstrating the capabilities of the model and may not represent an accurate account of the actual start-up procedures of the TOPAZ-II system. The temperature reactivity feedback effects of the moderator, UO[sub 2] fuel, electrodes, coolant, and other components in the core are calculated and their effects on the thermal and criticality conditions of the reactor are investigated. Also, estimates of the time constants of the temperature reactivity feedback for the UO[sub 2] fuel and the ZrH moderator during start-up, as well as of the total temperature reactivity feedback as a function of the reactor steady-state thermal power, are obtained.

  2. Optimization of steam-vortex plasma-torch start-up

    NASA Astrophysics Data System (ADS)

    Mikhailov, B. I.

    2011-12-01

    We propose a new optimal method of steam-vortex plasma-torches start-up; this method completely prevents the danger of water steam condensation in the arc chamber and all undesirable consequences of it.

  3. Proton exchange membrane fuel cells cold startup global strategy for fuel cell plug-in hybrid electric vehicle

    NASA Astrophysics Data System (ADS)

    Henao, Nilson; Kelouwani, Sousso; Agbossou, Kodjo; Dubé, Yves

    2012-12-01

    This paper investigates the Proton Exchange Membrane Fuel Cell (PEMFC) Cold Startup problem within the specific context of the Plugin Hybrid Electric Vehicles (PHEV). A global strategy which aims at providing an efficient method to minimize the energy consumption during the startup of a PEMFC is proposed. The overall control system is based on a supervisory architecture in which the Energy Management System (EMS) plays the role of the power flow supervisor. The EMS estimates in advance, the time to start the fuel cell (FC) based upon the battery energy usage during the trip. Given this estimation and the amount of additional energy required, the fuel cell temperature management strategy computes the most appropriate time to start heating the stack in order to reduce heat loss through the natural convection. As the cell temperature rises, the PEMFC is started and the reaction heat is used as a self-heating power source to further increase the stack temperature. A time optimal self-heating approach based on the Pontryagin minimum principle is proposed and tested. The experimental results have shown that the proposed approach is efficient and can be implemented in real-time on FC-PHEVs.

  4. Accelerated start-up of moving bed biofilm reactor by using a novel suspended carrier with porous surface.

    PubMed

    Chen, Xin; Kong, Lingjun; Wang, Xingyu; Tian, Shuanghong; Xiong, Ya

    2015-02-01

    A novel suspended carrier with porous surface was firstly prepared by coating a sponge on the inside and outside of a hard polyethylene ring. Herein the effects of the sponge thickness (0, 2, 4, 6 mm) and pore size (17, 45, 85 pores per inch, ppi) on the performance of the start-up stage in moving bed biofilm reactor (MBBR) were investigated. The results indicated that the home-made carrier with the sponge thickness of 4 mm and the pore size of 45 ppi, defined as SC4-45, showed the best performance, which obtained high biomass concentration of 2,136.6 mg/L, oxygen uptake rate for COD of 150.1 mg O2/h and oxygen uptake rate for NH4(+)-N of 17.4 mg O2/h. The DGGE profiles of the biofilms obtained in SC4-45 and a commercial carrier showed a similar community as the Dice similarity coefficients between two samples was 0.72. Furthermore, 16S rRNA gene sequence analysis reveals dominance of Sphaerotilus sp. and Aeromonas sp. in the community of both samples. Moreover, for the MBBR based on SC4-45, COD and NH4(+)-N removal rates reached 99.5 ± 1.1 and 93.6 ± 2.3 % at the end of the start-up stage, much higher than those of the commercial carrier, 74.9 ± 2.7 and 40.0 ± 1.8 %, respectively. These indicated the novel carrier obtained a quick start-up.

  5. Unocal makes progress on start-up - but faces lawsuit

    SciTech Connect

    Not Available

    1986-09-01

    Unocal's Parachute Creek oil shale facility was successfully run several days at a stretch for the first time this summer. After a shutdown of several months for modifications to the spent shale shaft cooler system, startup attempts began again in May. A 60 hour run was completed in July and then a six day run. In late August, Unocal began taking applications for 50 new jobs at the plant. The plant is scheduled to come back onstream in November after a 4 to 6 week maintenance turnaround. Meanwhile several congressmen and the Friends of the Earth have filed a lawsuit in the United States District Court for the District of Columbia against Unocal and the United States Treasury Department. The lawsuit attempts to void the agreement reached early this year between Unocal and the at-the-time disappearing United States Synthetic Fuels Corporation (SFC). That agreement changed $327 million of a $500 million price guarantee awarded to Unocal into a loan guarantee. The lawsuit charges that the agreement violated Congress' intent when they prohibited the SFC from issuing any new awards after December 19, 1985.

  6. Construction and startup experience for Milliken FGD Retrofit Project

    SciTech Connect

    Harvilla, J.; Mahlmeister, M.; Buchanan, T.; Jackson, C.; Watts, J.

    1996-12-01

    Under Round 4 of the U.S. Department of Energy`s Clean Coal Technology program, New York State Electric & Gas Corp. (NYSEG), in partnership with Saarbereg-Stebbins Engineering and Manufacturing Company, has retrofitted a formic acid enhanced forced oxidation wet limestone scrubber on Units 1 & 2 at the Milliken Steam Electric Station. Units 1 & 2 are 1950`s vintage Combustion Engineering tangentially fired pulverized coal units which are rated at nominal 150 MW each and operate in balanced draft mode. The FGD system for Unit 2 was placed into operation in January 1995 and the Unit 1 system in June, 1995. The project incorporates several unique aspects including low pH operation, a ceramic tile-lined cocurrent/countercurrent, split module absorber, a wet stack supported on the roof of the FGD building, and closed loop, zero liquid discharge operation producing commercial grade gypsum, and calcium chloride brine. The project objectives include 98% SO{sub 2} removal efficiency while burning high sulfur coal, the production of marketable byproducts to minimize solid waste disposal, zero wastewater discharge and space-saving design. The paper provides a brief overview of the project design, discusses construction and startup issues and presents early operating results. Process capital cost and economics of this design, procure and construct approach are reviewed relative to competing technologies.

  7. Construction and startup experience for the Milliken FGD retrofit project

    SciTech Connect

    Harvilla, J.; Mahlmeister, M.; Buchanan, T.; Jackson, C.; Watts, J.

    1996-10-01

    Under Round 4 of the US Department of Energy`s Clean Coal Technology program, NYSEG, in partnership with Saarberg-Holter-Umwelttechnik, Consolidation Coal Company and Stebbins Engineering and Manufacturing Company, has retrofitted a formic acid enhanced forced oxidation wet limestone scrubber on Units 1 and 2 at the Milliken Steam Electric Station. Units 1 and 2 are 1950`s vintage Combustion Engineering tangentially fired pulverized coal units which are rated at nominal 150 MW each and operate in balanced draft mode. The FGD system for Unit 2 was placed into operation in January 1995 and the Unit 1 system in June, 1995. The project incorporates several unique aspects including low pH operation, a ceramic tile-lined cocurrent/countercurrent, split module absorber, a wet stack supported on the roof of the FGD building, and closed loop, zero liquid discharge operation producing commercial grade gypsum, and calcium chloride brine. The project objectives include 98% SO{sub 2} removal efficiency while burning high sulfur coal, the production of marketable byproducts to minimize solid waste disposal, zero wastewater discharge and space-saving design. The paper provides a brief overview of the project design, discusses construction and startup issues and presents early operating results. Process capital cost and economics of this design, procure and construct approach are reviewed relative to competing technologies.

  8. Start-up rhetoric in eight speeches of Barack Obama.

    PubMed

    O'Connell, Daniel C; Kowal, Sabine; Sabin, Edward J; Lamia, John F; Dannevik, Margaret

    2010-10-01

    Our purpose in the following was to investigate the start-up rhetoric employed by U.S. President Barack Obama in his speeches. The initial 5 min from eight of his speeches from May to September of 2009 were selected for their variety of setting, audience, theme, and purpose. It was generally hypothesized that Barack Obama, widely recognized for the excellence of his rhetorical performance, would pursue both constant and variable strategies in his effort to establish contact with his audience. More specifically, it was hypothesized that the make-up of the audience--primarily native or non-native speakers of English--would be a prominent independent variable. A number of temporal and verbal measures were used as dependent variables. Variations were evident in mean length in syllables and duration in seconds of utterances (articulatory phrases), articulation rate in syllables per second of ontime, mean duration of silent pauses in seconds, and frequency of fillers, hesitations, colloquial words and phrases, introductory phrases, and 1st person singular pronominals. Results indicated that formality versus informality of the setting and presence or absence of a teleprompter were more prominent than native versus non-native audiences. Our analyses confirm Obama's skillfulness in challenging and variable settings and clearly detect orderliness and scientific generalizability in language use. The concept of orality/literacy provides a theoretical background and emphasizes dialogical interaction of audience and speaker.

  9. Startup, Commissioning and Operation of Fenyi 100MW CFB Boiler

    NASA Astrophysics Data System (ADS)

    Wang, Zhiwei; Yu, Wugao; Bo, Shi

    The first 100MW CFB boiler, designed by the Thermal Power Research Institute and manufactured by Harbin Boiler Company Limited, has been successfully running in Jiangxi Fenyi Power Plant since 2003. Local high ash content anthracite and lean coal that are very difficult to burn out are used in the 100 MW CFB boiler. The results of the 100MW CFB boiler shows that the CFB boiler can run in 30% MCR and startup with two under bed burners, and the boiler efficiency higher than 88% can be got after the combustion modification test. The CFB boiler can be operated with full load and reaches design parameters. The emissions of NO, N2O and CO are less than 7Omg/m3, 30mg/m3, and 125mg/m3, respectively, and SO2 less than 400mg/m3 after limestone injection. The bottom ash temperature from bed ash coolers is less than 120°C after its modification. Coal blockage at the coal storage silo is the main problem influencing the CFB boiler continuous operation. The running experiences for 5 years proved that the CFB boiler performance is successful, and the results were applied in 210 MW and 330 MW CFB Boiler design of Fenyi Power Plant.

  10. Startup, shutdown and malfunction plans coming for large industrial boilers

    SciTech Connect

    Kasarabada, A.N.

    2007-08-15

    The US Boiler MACT (maximum achievable control technology) regulations (codified under 40 CFR Part 63) in its current form requires existing large coal-fired industrial and utility boilers (under 25 MW) to meet emission limits for particulate matter or total selected metals, mercury and hydrogen chloride, as well as other operational limits. The MACT provision also requires affected facilities to develop startup, shutdown and malfunction plans (SSMP). The original date for Boiler MACT compliance for existing units had been 13 September 2007. However, on 8 June the US Court of Appeals for the District of Columbia issued an order effectively killing all existing MACT rules for industrial boilers. The Court instructed the US EPA to rewrite two sets of regulations. (Prior to April 2006 the MACT general provisions said the SSMPs needed to be 'developed and implemented'.) It seems unlikely that any new revision of the Boiler MACT by the EPA will take effect before mid-2008. Regardless of which direction the MACT rule is headed, now is the time to be prepared to comply with the SSMP requirements. The article sets out recommended steps for developing an effective SSMP.

  11. Start-up rhetoric in eight speeches of Barack Obama.

    PubMed

    O'Connell, Daniel C; Kowal, Sabine; Sabin, Edward J; Lamia, John F; Dannevik, Margaret

    2010-10-01

    Our purpose in the following was to investigate the start-up rhetoric employed by U.S. President Barack Obama in his speeches. The initial 5 min from eight of his speeches from May to September of 2009 were selected for their variety of setting, audience, theme, and purpose. It was generally hypothesized that Barack Obama, widely recognized for the excellence of his rhetorical performance, would pursue both constant and variable strategies in his effort to establish contact with his audience. More specifically, it was hypothesized that the make-up of the audience--primarily native or non-native speakers of English--would be a prominent independent variable. A number of temporal and verbal measures were used as dependent variables. Variations were evident in mean length in syllables and duration in seconds of utterances (articulatory phrases), articulation rate in syllables per second of ontime, mean duration of silent pauses in seconds, and frequency of fillers, hesitations, colloquial words and phrases, introductory phrases, and 1st person singular pronominals. Results indicated that formality versus informality of the setting and presence or absence of a teleprompter were more prominent than native versus non-native audiences. Our analyses confirm Obama's skillfulness in challenging and variable settings and clearly detect orderliness and scientific generalizability in language use. The concept of orality/literacy provides a theoretical background and emphasizes dialogical interaction of audience and speaker. PMID:20151192

  12. Influence of pulsation on start-up of UASB reactors.

    PubMed

    Franco, A; Gresia, G; Roca, E; Rozzi, A; Lema, J M

    2002-01-01

    The aim of this work is to study the influence of pulsation on the start-up of lab-scale UASB reactors. Pulsation was produced by an Elastic Membrane Pulsator (EMP). The application of this device in previous works improved the performance of continuous fixed-bed fermentors and reduced the formation of preferential pathways, the retention of gas metabolites within the bed and the resistance to mass transfer. These characteristics seem to be suitable for feeding UASB reactors. In this work, the influence of pulsation frequency was studied in two pulsed UASB reactors operated in parallel with a non-pulsed one. One of them (P1) operated at high frequencies (periods of 50 and 200 s between each pulsation) and the other (P2) at low frequencies (periods of 3600 and 900 s between each pulsation). An important improvement of the removal efficiency for pulsed reactors with respect to the non-pulsed one was obtained. The structure of the biomass was observed at the end of the process by scanning electron microscopy. In general, granulation of biomass was improved when operating in pulsing form.

  13. LESSONS LEARNED - STARTUP AND TRANSITION TO OPERATIONS AT THE 200 WEST PUMP AND TREAT FACILITY

    SciTech Connect

    FINK DE; BERGQUIST GG; BURKE SP

    2012-10-03

    This document lists key Lessons Learned from the Startup Team for the 200 West Pump and Treat Facility Project. The Startup Team on this Project was an integrated, multi-discipline team whose scope was Construction Acceptance Testing (CAT), functional Acceptance Testing Procedures (ATP), and procedure development and implementation. Both maintenance and operations procedures were developed. Included in the operations procedures were the process unit operations. In addition, a training and qualification program was also part of the scope.

  14. Patterns in Student Perceptions of Start-Up and Conversion Small High Schools

    ERIC Educational Resources Information Center

    Feldman, Jay; O'Dwyer, Anne

    2010-01-01

    Schools created as part of the small schools movement have been in operation for almost a decade, allowing identification of patterns in their growth. This study examines 4 years of survey data on 12 start-up and 13 conversion small high schools. Start-up small schools, almost all of which began with one grade level and grew by one grade per year,…

  15. 26 CFR 1.195-1T - Election to amortize start-up expenditures (temporary).

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... prior to September 8, 2008, see § 1.195-1 in effect prior to that date (§ 1.195-1 as contained in 26 CFR... 26 Internal Revenue 3 2011-04-01 2011-04-01 false Election to amortize start-up expenditures... Corporations (continued) § 1.195-1T Election to amortize start-up expenditures (temporary). (a) In...

  16. 26 CFR 1.195-1 - Election to amortize start-up expenditures.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... effect prior to that date (§ 1.195-1 as contained in 26 CFR part 1 edition revised as of April 1, 2008). ... 26 Internal Revenue 3 2013-04-01 2013-04-01 false Election to amortize start-up expenditures. 1... (continued) § 1.195-1 Election to amortize start-up expenditures. (a) In general. Under section 195(b),...

  17. 26 CFR 1.195-1 - Election to amortize start-up expenditures.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... effect prior to that date (§ 1.195-1 as contained in 26 CFR part 1 edition revised as of April 1, 2008). ... 26 Internal Revenue 3 2014-04-01 2014-04-01 false Election to amortize start-up expenditures. 1... (continued) § 1.195-1 Election to amortize start-up expenditures. (a) In general. Under section 195(b),...

  18. 26 CFR 1.195-1 - Election to amortize start-up expenditures.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... effect prior to that date (§ 1.195-1 as contained in 26 CFR part 1 edition revised as of April 1, 2008). ... 26 Internal Revenue 3 2012-04-01 2012-04-01 false Election to amortize start-up expenditures. 1... (continued) § 1.195-1 Election to amortize start-up expenditures. (a) In general. Under section 195(b),...

  19. Sharing Technology-Based Activity Ideas with Others.

    ERIC Educational Resources Information Center

    Seymour, Richard D.

    2003-01-01

    Discusses how to share technology-based lessons with other teachers. Includes an outline for documenting activity suggestions and offers recommendations for preparing print resources for colleagues. Includes essential elements of a published technology-based activity. (JOW)

  20. Magnesium Based Materials and their Antimicrobial Activity

    NASA Astrophysics Data System (ADS)

    Robinson, Duane Allan

    The overall goals of this body of work were to characterize the antimicrobial properties of magnesium (Mg) metal and nano-magnesium oxide (nMgO) in vitro, to evaluate the in vitro cytotoxicity of Mg metal, and to incorporate MgO nanoparticles into a polymeric implant coating and evaluate its in vitro antimicrobial properties. In the course of this work it was found that Mg metal, Mg-mesh, and nMgO have in vitro antimicrobial properties that are similar to a bactericidal antibiotic. For Mg metal, the mechanism of this activity appears to be related to an increase in pH (i.e. a more alkaline environment) and not an increase in Mg2+. Given that Mg-mesh is a Mg metal powder, the assumption is that it has the same mechanism of activity as Mg metal. The mechanism of activity for nMgO remains to be elucidated and may be related to a combination of interaction of the nanoparticles with the bacteria and the alkaline pH. It was further demonstrated that supernatants from suspensions of Mg-mesh and nMgO had the same antimicrobial effect as was noted when the particles were used. The supernatant from Mg-mesh and nMgO was also noted to prevent biofilm formation for two Staphylococcus strains. Finally, poly-epsilon-caprolactone (PCL) composites of Mg-mesh (PCL+Mg-mesh) and nMgO (PCL+nMgO) were produced. Coatings applied to screws inhibited growth of Escherichia coli and Pseudomonas aeruginosa and in thin disc format inhibited the growth of Staphylococcus aureus in addition to the E. coli and P. aeruginosa. Pure Mg metal was noted to have some cytotoxic effect on murine fibroblast and osteoblast cell lines, although this effect needs to be characterized further. To address the need for an in vivo model for evaluating implant associated infections, a new closed fracture osteomyelitis model in the femur of the rat was developed. Magnesium, a readily available and inexpensive metal was shown to have antimicrobial properties that appear to be related to its corrosion products and

  1. Successful start-up of the anammox process: Influence of the seeding strategy on performance and granule properties.

    PubMed

    Chen, Hui; Hu, Hai-Yan; Chen, Qian-Qian; Shi, Man-Ling; Jin, Ren-Cun

    2016-07-01

    Successful start-up of the anaerobic ammonium oxidation (anammox) process in up-flow sludge blanket reactor was achieved by seeding denitrifying (R0) or mixed denitrifying-anammox granular sludge at a 3:1 volume ratio (R1). The results demonstrated that R1 was successfully started-up on day 40 and had a nitrogen removal rate (NRR) of 0.55kgNm(-3)d(-1). By contrast, it took 98days to start up R0 (0.54kgNm(-3)d(-1)). R0 and R1 achieved maximum NRRs of 5.70 and 12.02kgNm(-3)d(-1), respectively. The biogranules from R1 generally possessed greater specific anammox activity (SAA), higher extracellular polymeric substance (EPS) and heme c content, larger granules and greater settling velocity. Quantitative PCR (qPCR) and high-throughput sequencing techniques were used to monitor the evolution of the bacterial community. These results demonstrated the feasibility of seeding mixed denitrifying-anammox granular sludge to start-up an anammox reactor. PMID:27043054

  2. Start-up vortex flow past an accelerated flat plate

    NASA Astrophysics Data System (ADS)

    Xu, Ling; Nitsche, Monika

    2015-03-01

    Viscous flow past a finite flat plate accelerating in the direction normal to itself is studied numerically. The plate moves with nondimensional speed tp, where p = 0, 1/2, 1, 2. The work focuses on resolving the flow at early to moderately large times and determining the dependence on the acceleration parameter p. Three stages in the vortex evolution are identified and quantified. The first stage, referred to as the Rayleigh stage [Luchini and Tognaccini, "The start-up vortex issuing from a semi-infinite flat plate," J. Fluid Mech. 455, 175-193 (2002)], consists of a vortical boundary layer of roughly uniform thickness surrounding the plate and its tip, without any separating streamlines. This stage is present only for p > 0, for a time-interval that scales like p3, as p → 0. The second stage is one of self-similar growth. The vortex trajectory and circulation satisfy inviscid scaling laws, the boundary layer thickness satisfies viscous laws. The self-similar trajectory starts immediately after the Rayleigh stage ends and lasts until the plate has moved a distance d = 0.5 to 1 times its length. Finally, in the third stage, the image vorticity due to the finite plate length becomes relevant and the flow departs from self-similar growth. The onset of an instability in the outer spiral vortex turns is also observed, however, at least for the zero-thickness plate considered here, it is shown to be easily triggered numerically by underresolution. The present numerical results are compared with experimental results of Pullin and Perry ["Some flow visualization experiments on the starting vortex," J. Fluid Mech. 97, 239-255 (1980)], and numerical results of Koumoutsakos and Shiels ["Simulations of the viscous flow normal to an impulsively started and uniformly accelerated flat plate," J. Fluid Mech. 328, 177-227 (1996)].

  3. Performance Based Education. Technology Activity Modules.

    ERIC Educational Resources Information Center

    Custer, Rodney L., Ed.

    These Technology Activity Modules are designed to serve as an implementation resource for technology education teachers as they integrate technology education with Missouri's Academic Performance Standards and provide a source of activities and activity ideas that can be used to integrate and reinforce learning across the curriculum. The modules…

  4. Startup of the Fission Converter Epithermal Neutron Irradiation Facility at the MIT Reactor

    SciTech Connect

    Newton, Thomas H. Jr.; Riley, Kent J.; Binns, Peter J.; Kohse, Gordon E.; Hu Linwen; Harling, Otto K.

    2002-08-15

    A new epithermal neutron irradiation facility, based on a fission converter assembly placed in the thermal column outside the reactor core, has been put into operation at the Massachusetts Institute of Technology Research Reactor (MITR). This facility was constructed to provide a high-intensity, forward-directed beam for use in neutron capture therapy with an epithermal flux of [approximately equal to]10{sup 10} n/cm{sup 2}.s at the medical room entrance with negligible fast neutron and gamma-ray contamination. The fission converter assembly consists of 10 or 11 MITR fuel elements placed in an aluminum tank and cooled with D{sub 2}O. Thermal-hydraulic criteria were established based on heat deposition calculations. Various startup tests were performed to verify expected neutronic and thermal-hydraulic behavior. Flow testing showed an almost flat flow distribution across the fuel elements with <5% bypass flow. The total reactivity change caused by operation of the facility was measured at 0.014 {+-} 0.002% {delta}K/K. Thermal power produced by the facility was measured to be 83.1 {+-} 4.2 kW. All of these test results satisfied the thermal-hydraulic safety criteria. In addition, radiation shielding design measurements were made that verified design calculations for the neutronic performance.

  5. Adaption of microbial community during the start-up stage of a thermophilic anaerobic digester treating food waste.

    PubMed

    Wu, Bo; Wang, Xing; Deng, Ya-Yue; He, Xiao-Lan; Li, Zheng-Wei; Li, Qiang; Qin, Han; Chen, Jing-Tao; He, Ming-Xiong; Zhang, Min; Hu, Guo-Quan; Yin, Xiao-Bo

    2016-10-01

    A successful start-up enables acceleration of anaerobic digestion (AD) into steady state. The microbial community influences the AD performance during the start-up. To investigate how microbial communities changed during the start-up, microbial dynamics was analyzed via high-throughput sequencing in this study. The results confirmed that the AD was started up within 25 d. Thermophilic methanogens and bacterial members functioning in hydrolysis, acidogenesis, and syntrophic oxidation became predominant during the start-up stage, reflecting a quick adaption of microorganisms to operating conditions. Such predominance also indicated the great contribution of these members to the fast start-up of AD. Redundancy analysis confirmed that the bacterial abundance significantly correlated with AD conditions. The stable ratio of hydrogenotrophic methanogens to aceticlastic methanogens is also important to maintain the stability of the AD process. This work will be helpful to understand the contribution of microbial community to the start-up of AD.

  6. Water transport during startup and shutdown of polymer electrolyte fuel cell stacks

    NASA Astrophysics Data System (ADS)

    Wang, X.; Tajiri, K.; Ahluwalia, R. K.

    A dynamic three-phase transport model is developed to analyze water uptake and transport in the membrane and catalyst layers of polymer electrolyte fuel cells during startup from subfreezing temperatures and subsequent shutdown. The initial membrane water content (λ, the number of water molecules per sulfonic acid site) is found to be an important parameter that determines whether a successful unassisted self-start is possible. For a given initial subfreezing temperature at startup, there is a critical λ (λ h), above which self-start is not possible because the product water completely engulfs the catalyst layers with ice before the stack can warm-up to 0 °C. There is a second value of λ (λ l), below which the stack can be self-started without forming ice. Between λ l and λ h, the stack can be self-started, but with intermediate formation of ice that melts as the stack warms up to 0 °C. Both λ l and λ h are functions of the initial stack temperature, cell voltage at startup, membrane thickness, catalyst loading, and stack heat capacity. If the stack is purged during the previous shutdown by flowing air in the cathode passages, then depending on the initial amount of water in the membrane and gas diffusion layers and the initial stack temperature, it may not be possible to dry the membrane to the critical λ for a subsequent successful startup. There is an optimum λ for robust and rapid startup and shutdown. Startup and shutdown time and energy may be unacceptable if the λ is much less than the optimum. Conversely, a robust startup from subfreezing temperatures cannot be assured if the λ is much higher than this optimum.

  7. Water transport during startup and shutdown of polymer electrolyte fuel cell stacks.

    SciTech Connect

    Wang, X.; Tajiri, K.; Ahluwalia, R.; Nuclear Engineering Division

    2010-10-01

    A dynamic three-phase transport model is developed to analyze water uptake and transport in the membrane and catalyst layers of polymer electrolyte fuel cells during startup from subfreezing temperatures and subsequent shutdown. The initial membrane water content (?, the number of water molecules per sulfonic acid site) is found to be an important parameter that determines whether a successful unassisted self-start is possible. For a given initial subfreezing temperature at startup, there is a critical ? (?h), above which self-start is not possible because the product water completely engulfs the catalyst layers with ice before the stack can warm-up to 0 C. There is a second value of ? (?l), below which the stack can be self-started without forming ice. Between ?l and ?h, the stack can be self-started, but with intermediate formation of ice that melts as the stack warms up to 0 C. Both ?l and ?h are functions of the initial stack temperature, cell voltage at startup, membrane thickness, catalyst loading, and stack heat capacity. If the stack is purged during the previous shutdown by flowing air in the cathode passages, then depending on the initial amount of water in the membrane and gas diffusion layers and the initial stack temperature, it may not be possible to dry the membrane to the critical ? for a subsequent successful startup. There is an optimum ? for robust and rapid startup and shutdown. Startup and shutdown time and energy may be unacceptable if the ? is much less than the optimum. Conversely, a robust startup from subfreezing temperatures cannot be assured if the ? is much higher than this optimum.

  8. Creating Stimulating Learning and Thinking Using New Models of Activity-Based Learning and Metacognitive-Based Activities

    ERIC Educational Resources Information Center

    Pang, Katherine

    2010-01-01

    The purpose of this paper is to present a novel way to stimulate learning, creativity, and thinking based on a new understanding of activity-based learning (ABL) and two methods for developing metacognitive-based activities for the classroom. ABL, in this model, is based on the premise that teachers are distillers and facilitators of information…

  9. Reduction of start-up time through bioaugmentation process in microbial fuel cells using an isolate from dark fermentative spent media fed anode.

    PubMed

    Pandit, Soumya; Khilari, Santimoy; Roy, Shantonu; Ghangrekar, M M; Pradhan, Debabrata; Das, Debabrata

    2015-01-01

    An electrochemically active bacteria Pseudomonas aeruginosa IIT BT SS1 was isolated from a dark fermentative spent media fed anode, and a bioaugmentation technique using the isolated strain was used to improve the start-up time of a microbial fuel cell (MFC). Higher volumetric current density and lower start-up time were observed with the augmented system MFC-PM (13.7 A/m(3)) when compared with mixed culture MFC-M (8.72 A/m(3)) during the initial phase. This enhanced performance in MFC-PM was possibly due to the improvement in electron transfer ability by the augmented strain. However, pure culture MFC-P showed maximum volumetric current density (17 A/m(3)) due to the inherent electrogenic properties of Pseudomonas sp. An electrochemical impedance spectroscopic (EIS) study, along with matrix-assisted laser desorption/ionization-time-of-flight (MALDI-TOF) analysis, supported the influence of isolated species in improving the MFC performance. The present study indicates that the bioaugmentation strategy using the isolated Pseudomonas sp. can be effectively utilized to decrease the start-up time of MFC.

  10. Advanced automation concepts applied to Experimental Breeder Reactor-II startup

    SciTech Connect

    Berkan, R.C.; Upadhyaya, B.R.; Bywater, R.L. . Dept. of Nuclear Engineering); Kisner, R.A. )

    1991-08-01

    The major objective of this work is to demonstrate through simulations that advanced liquid-metal reactor plants can be operated from low power by computer control. Development of an automatic control system with this objective will help resolve specific issues and provide proof through demonstration that automatic control for plant startup is feasible. This paper presents an advanced control system design for startup of the Experimental Breeder Reactor-2 (EBR-2) located at Idaho Falls, Idaho. The design incorporates recent methods in nonlinear control with advanced diagnostics techniques such as neural networks to form an integrated architecture. The preliminary evaluations are obtained in a simulated environment by a low-order, valid nonlinear model. Within the framework of phase 1 research, the design includes an inverse dynamics controller, a fuzzy controller, and an artificial neural network controller. These three nonlinear control modules are designed to follow the EBR-2 startup trajectories in a multi-input/output regime. They are coordinated by a supervisory routine to yield a fault-tolerant, parallel operation. The control system operates in three modes: manual, semiautomatic, and fully automatic control. The simulation results of the EBR-2 startup transients proved the effectiveness of the advanced concepts. The work presented in this paper is a preliminary feasibility analysis and does not constitute a final design of an automated startup control system for EBR-2. 14 refs., 43 figs.

  11. Frozen start-up behavior of low-temperature heat pipes

    NASA Technical Reports Server (NTRS)

    Faghri, Amir

    1992-01-01

    Start-up and subsequent operation of a low-temperature heat pipe requires the liquid phase of the operating fluid to be continuously pumped back to the evaporator by the capillary action of the wick. If the pipe has been in an environment where ambient temperatures are below the freezing point of the working fluid prior to start-up, the frozen fluid in the condenser and adiabatic region scan prevent initial flow to the evaporator, causing dryout of the evaporator before all of the working fluid is in the liquid phase. This paper examines the time-dependent wall and vapor temperature profiles along the axial length of a low-temperature heat pipe during start-up from the frozen state, and freeze-out during a normal operation by applying a subfreezing temperature fluid through the condenser. In addition, the experimental transient frozen start-up wall temperature profile is compared with a two-dimensional numerical phase-change model. A successful start-up method using a pulsed power input is presented.

  12. Influence of the type and source of inoculum on the start-up of anammox sequencing batch reactors (SBRs).

    PubMed

    Guerrero, Lorna; Van Diest, Federico; Barahona, Andrea; Montalvo, Silvio; Borja, Rafael

    2013-01-01

    Anammox (anaerobic ammonium oxidation) is an attractive option for the treatment of wastewaters with a low carbon/nitrogen ratio. This is due to its low operating costs when compared to the classical nitrification-denitrification processes. However, one of the main disadvantages of the Anammox process is slow biomass growth, meaning a relatively slow reactor start-up. This becomes even more complicated when Anammox microorganisms are not present in the inoculum. Four inocula were studied for the start-up of Anammox sequencing batch reactors (SBRs) 2 L in volume agitated at 100 rpm, one of them using zeolite as a microbial support. Two inocula were taken from UASB reactors and two from aerobic reactors (activated sludge and SBR). The Anammox SBRs studied were operated at 36 ± 0.5°C. The results showed that the only inoculum that enabled the enrichment of the Anammox biomass came from an activated sludge plant treating wastewaters from a poultry slaughterhouse. This plant was designed for organic matter degradation and nitrogen removal (nitrification). This could explain the presence of Anammox microorganisms. This SBR operated without zeolite and achieved nitrite and ammonium removals of 96.3% and 68.4% respectively, at a nitrogen loading rate (NLR) of 0.1 kg N/m(3)/d in both cases. The lower ammonium removal was due to the fact that a sub-stoichiometric amount of nitrite (1 molar ratio) was fed. The specific Anammox activity (SAA) achieved was 0.18 g N/g VSS/d. PMID:23647121

  13. 3-D modeling of the start-up phase of DC casting of sheet ingots

    SciTech Connect

    Gruen, G.U.; Schneider, W.

    1996-10-01

    Three-dimensional transient simulations of the coupled fluid flow and heat transfer problem during the filling of the mold before the beginning of starting block movement have been used to investigate the influence of distributors and start-up programs on temperature and solidification front. As butt curl and possible hot tearing of the ingot are critically controlled by the temperature development of the metal in the mold, and the temperature itself depends on mold filling and start-up strategy, quality is strongly connected to appropriate metal distribution conditions in this early start-up phase. The calculated filling behavior and temperatures are discussed in dependency of parameters like distributor geometry or block shape. The simulations support the development of adjusted metal distribution systems.

  14. Assessment of Startup Fuel Options for the GNEP Advanced Burner Reactor (ABR)

    SciTech Connect

    Jon Carmack; Kemal O. Pasamehmetoglu; David Alberstein

    2008-02-01

    The Global Nuclear Energy Program (GNEP) includes a program element for the development and construction of an advanced sodium cooled fast reactor to demonstrate the burning (transmutation) of significant quantities of minor actinides obtained from a separations process and fabricated into a transuranic bearing fuel assembly. To demonstrate and qualify transuranic (TRU) fuel in a fast reactor, an Advanced Burner Reactor (ABR) prototype is needed. The ABR would necessarily be started up using conventional metal alloy or oxide (U or U, Pu) fuel. Startup fuel is needed for the ABR for the first 2 to 4 core loads of fuel in the ABR. Following start up, a series of advanced TRU bearing fuel assemblies will be irradiated in qualification lead test assemblies in the ABR. There are multiple options for this startup fuel. This report provides a description of the possible startup fuel options as well as possible fabrication alternatives available to the program in the current domestic and international facilities and infrastructure.

  15. Active Inquiry, Web-based Oceanography Exercises.

    ERIC Educational Resources Information Center

    Eckels-Martin, Ellen E.; Howell, Paul D.

    2001-01-01

    Discusses using web sites to develop active inquiry lessons that mimic some of the tasks and thought processes scientists use everyday. The exercises available at the web sites are designed to develop science process skills and convey basic course content. Exercises stress the interactions between the ocean and the atmosphere. (Author/SAH)

  16. Activity Based Astronomy for Primary Science Programs.

    ERIC Educational Resources Information Center

    Ginns, Ian

    Print materials in astronomy such as books, journals, charts, and posters are typically the sources of information for teachers and children about the moon, the sun, lunar and solar eclipses, planetary sizes, distances of planets from the sun, planetary atmospheres, and so on. This paper describes and analyzes a number of activities designed to…

  17. Teaching Activity-Based Taxicab Geometry

    ERIC Educational Resources Information Center

    Ada, Tuba

    2013-01-01

    This study aimed on the process of teaching taxicab geometry, a non-Euclidean geometry that is easy to understand and similar to Euclidean geometry with its axiomatic structure. In this regard, several teaching activities were designed such as measuring taxicab distance, defining a taxicab circle, finding a geometric locus in taxicab geometry, and…

  18. Description of data base management systems activities

    NASA Technical Reports Server (NTRS)

    1983-01-01

    One of the major responsibilities of the JPL Computing and Information Services Office is to develop and maintain a JPL plan for providing computing services to the JPL management and administrative community that will lead to improved productivity. The CISO plan to accomplish this objective has been titled 'Management and Administrative Support Systems' (MASS). The MASS plan is based on the continued use of JPL's IBM 3032 Computer system for administrative computing and for the MASS functions. The current candidate administrative Data Base Management Systems required to support the MASS include ADABASE, Cullinane IDMS and TOTAL. Previous uses of administrative Data Base Systems have been applied to specific local functions rather than in a centralized manner with elements common to the many user groups. Limited capacity data base systems have been installed in microprocessor based office automation systems in a few Project and Management Offices using Ashton-Tate dBASE II. These experiences plus some other localized in house DBMS uses have provided an excellent background for developing user and system requirements for a single DBMS to support the MASS program.

  19. Fast start-up reactor for partial oxidation of methane with electrically-heated metallic monolith catalyst

    NASA Astrophysics Data System (ADS)

    Jung, Heon; Yoon, Wang Lai; Lee, Hotae; Park, Jong Soo; Shin, Jang Sik; La, Howon; Lee, Jong Dae

    A palladium-washcoated metallic monolith catalyst is applied to the partial oxidation of methane to syngas. This catalyst is highly active at a gas hourly space velocity (GHSV) of 100,000 h -1. The compact partial oxidation (POX) reactor equipped with both 96 cc of the metallic monolith catalyst and an electrically-heated catalyst (EHC) has a start-up time of less than 1.5 min and a syngas generation capacity of 9.5 Nm 3 h -1. The POX reaction is sustained without the need for an external heater. With the stand-alone POX reactor, the methane conversion can be increased either by preheating the reactant mixture heat-exchanged with the product gas, or by supplying a larger amount of oxygen than is necessary for the reaction stoichiometry.

  20. Active index for content-based medical image retrieval.

    PubMed

    Chang, S K

    1996-01-01

    This paper introduces the active index for content-based medical image retrieval. The dynamic nature of the active index is its most important characteristic. With an active index, we can effectively and efficiently handle smart images that respond to accessing, probing and other actions. The main applications of the active index are to prefetch image and multimedia data, and to facilitate similarity retrieval. The experimental active index system is described. PMID:8954230

  1. Active index for content-based medical image retrieval.

    PubMed

    Chang, S K

    1996-01-01

    This paper introduces the active index for content-based medical image retrieval. The dynamic nature of the active index is its most important characteristic. With an active index, we can effectively and efficiently handle smart images that respond to accessing, probing and other actions. The main applications of the active index are to prefetch image and multimedia data, and to facilitate similarity retrieval. The experimental active index system is described.

  2. Cover and startup gas supply system for solid oxide fuel cell generator

    DOEpatents

    Singh, P.; George, R.A.

    1999-07-27

    A cover and startup gas supply system for a solid oxide fuel cell power generator is disclosed. Hydrocarbon fuel, such as natural gas or diesel fuel, and oxygen-containing gas are supplied to a burner. Combustion gas exiting the burner is cooled prior to delivery to the solid oxide fuel cell. The system mixes the combusted hydrocarbon fuel constituents with hydrogen which is preferably stored in solid form to obtain a non-explosive gas mixture. The system may be used to provide both non-explosive cover gas and hydrogen-rich startup gas to the fuel cell. 4 figs.

  3. Cover and startup gas supply system for solid oxide fuel cell generator

    DOEpatents

    Singh, Prabhakar; George, Raymond A.

    1999-01-01

    A cover and startup gas supply system for a solid oxide fuel cell power generator is disclosed. Hydrocarbon fuel, such as natural gas or diesel fuel, and oxygen-containing gas are supplied to a burner. Combustion gas exiting the burner is cooled prior to delivery to the solid oxide fuel cell. The system mixes the combusted hydrocarbon fuel constituents with hydrogen which is preferably stored in solid form to obtain a non-explosive gas mixture. The system may be used to provide both non-explosive cover gas and hydrogen-rich startup gas to the fuel cell.

  4. An investigation of the side force that is sometimes observed in rocket start-up

    NASA Technical Reports Server (NTRS)

    Bowyer, J. M., Jr.; Kreiter, G. W.; Petersen, R. E.

    1978-01-01

    The occurrence of a large but momentary side force during the start-up of rocket motors employing convergent-divergent nozzles has been noted occasionally. Asymmetric flow separation within the divergent section of the nozzle is proposed as the principal source of this lateral force. A method for estimating this force and its concomitant lateral impulse is outlined, and results obtained by applying the method to Scout vehicle first-, second-, and third-stage rocket motor start-ups are presented and compared with similar estimates that other researchers obtained by a different method.

  5. Transient three-dimensional startup side load analysis of a regeneratively cooled nozzle

    NASA Astrophysics Data System (ADS)

    Wang, Ten-See

    2009-07-01

    The objective of this effort is to develop a computational methodology to capture the side load physics and to anchor the computed aerodynamic side loads with the available data by simulating the startup transient of a regeneratively cooled, high-aspect-ratio nozzle, hot-fired at sea level. The computational methodology is based on an unstructured-grid, pressure-based, reacting flow computational fluid dynamics and heat transfer formulation, and a transient inlet history based on an engine system simulation. Emphases were put on the effects of regenerative cooling on shock formation inside the nozzle, and ramp rate on side load reduction. The results show that three types of asymmetric shock physics incur strong side loads: the generation of combustion wave, shock transitions, and shock pulsations across the nozzle lip, albeit the combustion wave can be avoided with sparklers during hot-firing. Results from both regenerative cooled and adiabatic wall boundary conditions capture the early shock transitions with corresponding side loads matching the measured secondary side load. It is theorized that the first transition from free-shock separation to restricted-shock separation is caused by the Coanda effect. After which the regeneratively cooled wall enhances the Coanda effect such that the supersonic jet stays attached, while the hot adiabatic wall fights off the Coanda effect, and the supersonic jet becomes detached most of the time. As a result, the computed peak side load and dominant frequency due to shock pulsation across the nozzle lip associated with the regeneratively cooled wall boundary condition match those of the test, while those associated with the adiabatic wall boundary condition are much too low. Moreover, shorter ramp time results show that higher ramp rate has the potential in reducing the nozzle side loads.

  6. Neutron counter based on beryllium activation

    SciTech Connect

    Bienkowska, B.; Prokopowicz, R.; Kaczmarczyk, J.; Paducha, M.; Scholz, M.; Igielski, A.; Karpinski, L.; Pytel, K.

    2014-08-21

    The fusion reaction occurring in DD plasma is followed by emission of 2.45 MeV neutrons, which carry out information about fusion reaction rate and plasma parameters and properties as well. Neutron activation of beryllium has been chosen for detection of DD fusion neutrons. The cross-section for reaction {sup 9}Be(n, α){sup 6}He has a useful threshold near 1 MeV, which means that undesirable multiple-scattered neutrons do not undergo that reaction and therefore are not recorded. The product of the reaction, {sup 6}He, decays with half-life T{sub 1/2} = 0.807 s emitting β{sup −} particles which are easy to detect. Large area gas sealed proportional detector has been chosen as a counter of β–particles leaving activated beryllium plate. The plate with optimized dimensions adjoins the proportional counter entrance window. Such set-up is also equipped with appropriate electronic components and forms beryllium neutron activation counter. The neutron flux density on beryllium plate can be determined from the number of counts. The proper calibration procedure needs to be performed, therefore, to establish such relation. The measurements with the use of known β–source have been done. In order to determine the detector response function such experiment have been modeled by means of MCNP5–the Monte Carlo transport code. It allowed proper application of the results of transport calculations of β{sup −} particles emitted from radioactive {sup 6}He and reaching proportional detector active volume. In order to test the counter system and measuring procedure a number of experiments have been performed on PF devices. The experimental conditions have been simulated by means of MCNP5. The correctness of simulation outcome have been proved by measurements with known radioactive neutron source. The results of the DD fusion neutron measurements have been compared with other neutron diagnostics.

  7. Neutron counter based on beryllium activation

    NASA Astrophysics Data System (ADS)

    Bienkowska, B.; Prokopowicz, R.; Scholz, M.; Kaczmarczyk, J.; Igielski, A.; Karpinski, L.; Paducha, M.; Pytel, K.

    2014-08-01

    The fusion reaction occurring in DD plasma is followed by emission of 2.45 MeV neutrons, which carry out information about fusion reaction rate and plasma parameters and properties as well. Neutron activation of beryllium has been chosen for detection of DD fusion neutrons. The cross-section for reaction 9Be(n, α)6He has a useful threshold near 1 MeV, which means that undesirable multiple-scattered neutrons do not undergo that reaction and therefore are not recorded. The product of the reaction, 6He, decays with half-life T1/2 = 0.807 s emitting β- particles which are easy to detect. Large area gas sealed proportional detector has been chosen as a counter of β-particles leaving activated beryllium plate. The plate with optimized dimensions adjoins the proportional counter entrance window. Such set-up is also equipped with appropriate electronic components and forms beryllium neutron activation counter. The neutron flux density on beryllium plate can be determined from the number of counts. The proper calibration procedure needs to be performed, therefore, to establish such relation. The measurements with the use of known β-source have been done. In order to determine the detector response function such experiment have been modeled by means of MCNP5-the Monte Carlo transport code. It allowed proper application of the results of transport calculations of β- particles emitted from radioactive 6He and reaching proportional detector active volume. In order to test the counter system and measuring procedure a number of experiments have been performed on PF devices. The experimental conditions have been simulated by means of MCNP5. The correctness of simulation outcome have been proved by measurements with known radioactive neutron source. The results of the DD fusion neutron measurements have been compared with other neutron diagnostics.

  8. Tracheal activity recognition based on acoustic signals.

    PubMed

    Olubanjo, Temiloluwa; Ghovanloo, Maysam

    2014-01-01

    Tracheal activity recognition can play an important role in continuous health monitoring for wearable systems and facilitate the advancement of personalized healthcare. Neck-worn systems provide access to a unique set of health-related data that other wearable devices simply cannot obtain. Activities including breathing, chewing, clearing the throat, coughing, swallowing, speech and even heartbeat can be recorded from around the neck. In this paper, we explore tracheal activity recognition using a combination of promising acoustic features from related work and apply simplistic classifiers including K-NN and Naive Bayes. For wearable systems in which low power consumption is of primary concern, we show that with a sub-optimal sampling rate of 16 kHz, we have achieved average classification results in the range of 86.6% to 87.4% using 1-NN, 3-NN, 5-NN and Naive Bayes. All classifiers obtained the highest recognition rate in the range of 97.2% to 99.4% for speech classification. This is promising to mitigate privacy concerns associated with wearable systems interfering with the user's conversations.

  9. Business Approach To Lunar Base Activation

    NASA Astrophysics Data System (ADS)

    Schmitt, Harrison H.

    2003-01-01

    It remains unlikely that any government or group of governments will make the long-term funding commitments necessary to return to the Moon in support of scientific goals or resource production. If a lunar base is to be established within the foreseeable future, it will support of commercial production and use of unique energy resources Business plan development for commercial production and use of lunar Helium-3 requires a number of major steps, including identification of the required investor base and development of fusion power technology through a series of business bridges that provide required rates of return.

  10. 30 CFR 250.1917 - What criteria for pre-startup review must be in my SEMS program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... SHELF Safety and Environmental Management Systems (SEMS) § 250.1917 What criteria for pre-startup review... my SEMS program? 250.1917 Section 250.1917 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL...-startup safety and environmental review for new and significantly modified facilities that are subject...

  11. 30 CFR 250.1917 - What criteria for pre-startup review must be in my SEMS program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... SHELF Safety and Environmental Management Systems (SEMS) § 250.1917 What criteria for pre-startup review... my SEMS program? 250.1917 Section 250.1917 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL...-startup safety and environmental review for new and significantly modified facilities that are subject...

  12. 30 CFR 250.1917 - What criteria for pre-startup review must be in my SEMS program?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... SHELF Safety and Environmental Management Systems (SEMS) § 250.1917 What criteria for pre-startup review... my SEMS program? 250.1917 Section 250.1917 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL...-startup safety and environmental review for new and significantly modified facilities that are subject...

  13. Evaluation of an Internet, Stage-Based Physical Activity Intervention.

    ERIC Educational Resources Information Center

    Hager, Ronald L.; Hardy, Aaron; Aldana, Steven G.; George, James D.

    2002-01-01

    Evaluated the impact of online, stage-based materials on exercise behavior and stage of readiness to change. College faculty participated in stage-based, action-message, or control groups. Occupational and leisure activity, 7-day physical activity, exercise self-efficacy, and stage of readiness to change were assessed at baseline and 6 weeks.…

  14. Creating Evidence-Based Research in Adapted Physical Activity

    ERIC Educational Resources Information Center

    Reid, Greg; Bouffard, Marcel; MacDonald, Catherine

    2012-01-01

    Professional practice guided by the best research evidence is a usually referred to as evidence-based practice. The aim of the present paper is to describe five fundamental beliefs of adapted physical activity practices that should be considered in an 8-step research model to create evidence-based research in adapted physical activity. The five…

  15. Behavioral Activation Is an Evidence-Based Treatment for Depression

    ERIC Educational Resources Information Center

    Sturmey, Peter

    2009-01-01

    Recent reviews of evidence-based treatment for depression did not identify behavioral activation as an evidence-based practice. Therefore, this article conducted a systematic review of behavioral activation treatment of depression, which identified three meta-analyses, one recent randomized controlled trial and one recent follow-up of an earlier…

  16. Improving hospital cost accounting with activity-based costing.

    PubMed

    Chan, Y C

    1993-01-01

    In this article, activity-based costing, an approach that has proved to be an improvement over the conventional costing system in product costing, is introduced. By combining activity-based costing with standard costing, health care administrators can better plan and control the costs of health services provided while ensuring that the organization's bottom line is healthy.

  17. Activity-based costing management in a private practice setting.

    PubMed

    Carlomagno, M; Draper, V

    1997-01-01

    Activity-based costing is a method of calculating cost of a service, focusing on operations. It gives quick and tangible cost information to operations and financial managers. While this method has be used more in the manufacturing area, it is gaining acceptance in the medical practice. This article describes activity-based costing and illustrates how to start utilizing it in a practice.

  18. A Profile of Latino School-Based Extracurricular Activity Involvement

    ERIC Educational Resources Information Center

    Peguero, Anthony A.

    2010-01-01

    Participation in school-based extracurricular activities influences educational success. Thus, it is important to depict a profile of school-based extracurricular activity involvement for a Latino student population that is marginalized in schools. This research uses the Educational Longitudinal Study of 2002 and logistic regression analyses to…

  19. Construction and start-up of a 250 kW natural gas fueled MCFC demonstration power plant

    SciTech Connect

    Figueroa, R.A.; Carter, J.; Rivera, R.; Otahal, J.

    1996-12-31

    San Diego Gas & Electric (SDG&E) is participating with M-C Power in the development and commercialization program of their internally manifolded heat exchanger (IMHEX{reg_sign}) carbonate fuel cell technology. Development of the IMHEX technology base on the UNOCAL test facility resulted in the demonstration of a 250 kW thermally integrated power plant located at the Naval Air Station at Miramar, California. The members of the commercialization team lead by M-C Power (MCP) include Bechtel Corporation, Stewart & Stevenson Services, Inc., and Ishikawajima-Harima Heavy Industries (IHI). MCP produced the fuel cell stack, Bechtel was responsible for the process engineering including the control system, Stewart & Stevenson was responsible for packaging the process equipment in a skid (pumps, desulfurizer, gas heater, turbo, heat exchanger and stem generator), IHI produced a compact flat plate catalytic reformer operating on natural gas, and SDG&E assumed responsibility for plant construction, start-up and operation of the plant.

  20. Remote temperature measurements of a cold start-up on a low pressure steam turbine using phosphor thermography

    SciTech Connect

    Allison, S.W.; Beshears, D.L.; Cates, M.R.; Cunningham, G.T.; Puri, A.; Schuster, L.

    1995-12-31

    The feasibility of using a noncontact, optical method for temperature measurement based on thermographic phosphors was explored during the cold start-up of a low pressure turbine rotor at the TVA Cumberland Steam Plant. A simple optical system delivered low power laser light to a segment of the balance rim and balance weight holes which were coated with phosphor. From analysis of the laser induced fluorescence, temperatures ranging from 37C (99 F) to 121 C (250 F) were determined. There was no discernible condensation of steam on the viewing port optics. This transient temperature history at the exit end of the LP rotor may help to determine the root cause of a recent blade failure experienced in the L-0 blade row of a unit at this plant during an overspeed test.

  1. Availability of hydrogen for lunar base activities

    NASA Technical Reports Server (NTRS)

    Bustin, Roberta; Gibson, Everett K., Jr.

    1992-01-01

    Hydrogen will be needed on a lunar base to make water for consumables, to provide fuel, and to serve as a reducing agent in the extraction of oxygen from lunar minerals. This study was undertaken in order to learn more about the abundance and distribution of solar-wind-implanted hydrogen. Hydrogen was found in all samples studied, with concentrations, varying widely depending on soil maturity, grain size, and mineral composition. Seven cores returned from the Moon were studied. Although hydrogen was implanted in the upper surface layer of the regolith, it was found throughout the cores due to micrometeorite reworking of the soil.

  2. Availability of hydrogen for lunar base activities

    NASA Technical Reports Server (NTRS)

    Bustin, Roberta

    1990-01-01

    Hydrogen will be needed on a lunar base to make water for consumables, to provide fuel, and to serve as reducing agent in the extraction of oxygen from lunar minerals. The abundance and distribution of solar wind implanted hydrogen were studied. Hydrogen was found in all samples studied with concentrations varying widely depending on soil maturity, grain size, and mineral composition. Seven cores returned from the moon were studied. Although hydrogen was implanted in the upper surface layer of the regolith, it was found throughout the cores due to micrometeorite reworking of the soil.

  3. Start-up fuel and power flattening of sodium-cooled candle core

    SciTech Connect

    Takaki, Naoyuki; Sagawa, Yu; Umino, Akitake; Sekimoto, Hiroshi

    2013-07-01

    The hard neutron spectrum and unique power shape of CANDLE enable its distinctive performances such as achieving high burnup more than 30% and exempting necessity of both enrichment and reprocessing. On the other hand, they also cause several challenging problems. One is how the initial fuel can be prepared to start up the first CANDLE reactor because the equilibrium fuel composition that enables stable CANDLE burning is complex both in axial and radial directions. Another prominent problem is high radial power peaking factor that worsens averaged burnup, namely resource utilization factor in once-through mode and shorten the life time of structure materials. The purposes of this study are to solve these two problems. Several ideas for core configurations and startup fuel using single enrichment uranium and iron as a substitute of fission products are studied. As a result, it is found that low enriched uranium is applicable to ignite the core but all concepts examined here exceeded heat limits. Adjustment in enrichment and height of active and burnt zone is opened for future work. Sodium duct assemblies and thorium fuel assemblies loaded in the center region are studied as measures to reduce radial power peaking factor. Replacing 37 fuels by thorium fuel assemblies in the zeroth to third row provides well-balanced performance with flattened radial power distribution. The CANDLE core loaded with natural uranium in the outer and thorium in the center region achieved 35.6% of averaged burnup and 7.0 years of cladding life time owing to mitigated local fast neutron irradiation at the center. Using thorium with natural or depleted uranium in CANDLE reactor is also beneficial to diversifying fission resource and extending available term of fission energy without expansion of needs for enrichment and reprocessing.

  4. THE MURMANSK INITIATIVE - RF: COMPLETING CONSTRUCTION AND START-UP TESTING

    SciTech Connect

    CZAJKOWSKI,C.; BOWERMAN,B.S.; DYER,R.S.; SORLIE,A.A.; WESTER,D.

    1998-03-01

    The Murmansk Initiative - RF was instigated to address Russia's ability to meet the London Convention prohibiting ocean dumping of radioactive waste. The Initiative, under a trilateral agreement, will upgrade an existing low-level liquid radioactive waste treatment facility, increasing capacity from 1,200 m{sup 3}/year to 5,000 m{sup 3}/year, and expand the capability to treat liquids containing salt (up to 10 g/L). The three parties to the agreement, the Russian Federation, Norway, and the US, have split the costs for the project. All construction has been provided by Russia. Construction of mechanical systems (piping and valves, pumps, sorbent columns, settling tanks, surge tanks) is nearly complete, with instrumentation and control (I+C) systems the last to be installed. Delays to the I+C installation have occurred because changes in system specifications required some additional US-supplied computer control equipment to be purchased, and clearance through customs (both US and Russian) has been slow. Start-up testing has been limited to testing of some isolated sub-systems because of the delays in I+C installation. Final construction activities are also hampered by the current state of the Russian economy. The specific impact has been completion of the cementation unit, which was not funded under the trilateral agreement (but funded by the Russian government). Russian regulatory authorities have stated that final licensing for expanded capacity (5,000 m{sup 3}/year) will not be given until the cementation unit is on-line.

  5. Graduate Career-Making and Business Start-Up: A Literature Review

    ERIC Educational Resources Information Center

    Nabi, Ghulam; Holden, Rick; Walmsley, Andreas

    2006-01-01

    Purpose: The purpose of this article is to provide a selective review of literature on the career-related decision-making processes in terms of the transition from student to business start-up, and the nature and influence of support and guidance. Design/methodology/approach: Primarily, a critical review of a range of recently published literature…

  6. Ed Tech Developer's Guide: A Primer for Software Developers, Startups, and Entrepreneurs

    ERIC Educational Resources Information Center

    Bienkowski, Marie; Gerard, Sarah Nixon; Rubin, Shawn; Sanford, Cathy; Borrelli-Murray, Dana; Driscoll, Tom; Arora, Jessie; Hruska, Mike; Beck, Katie; Murray, Thomas; Hoekstra, Jason; Gannes, Stuart; Metz, Edward; Midgley, Steve; Castilla, Stephanie; Tomassini, Jason; Madda, Mary Jo; Chase, Zac; Martin, Erik; Noel, Marcus; Styles, Kathleen

    2015-01-01

    Opportunities abound for software designers and developers to create impactful tools for teachers, school leaders, students, and their families. This guide for developers, startups, and entrepreneurs addresses key questions about the education ecosystem and highlights critical needs and opportunities to develop digital tools and apps for learning.…

  7. 40 CFR 63.310 - Requirements for startups, shutdowns, and malfunctions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CATEGORIES National Emission Standards for Coke Oven Batteries § 63.310 Requirements for startups, shutdowns... or operator shall operate and maintain the coke oven battery and its pollution control equipment... operator of a coke oven battery shall develop, according to paragraph (c) of this section, a...

  8. 40 CFR 63.310 - Requirements for startups, shutdowns, and malfunctions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CATEGORIES National Emission Standards for Coke Oven Batteries § 63.310 Requirements for startups, shutdowns... or operator shall operate and maintain the coke oven battery and its pollution control equipment... operator of a coke oven battery shall develop, according to paragraph (c) of this section, a...

  9. 40 CFR 63.310 - Requirements for startups, shutdowns, and malfunctions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CATEGORIES National Emission Standards for Coke Oven Batteries § 63.310 Requirements for startups, shutdowns... or operator shall operate and maintain the coke oven battery and its pollution control equipment... operator of a coke oven battery shall develop, according to paragraph (c) of this section, a...

  10. 40 CFR 63.310 - Requirements for startups, shutdowns, and malfunctions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CATEGORIES National Emission Standards for Coke Oven Batteries § 63.310 Requirements for startups, shutdowns... or operator shall operate and maintain the coke oven battery and its pollution control equipment... operator of a coke oven battery shall develop, according to paragraph (c) of this section, a...

  11. 40 CFR 63.310 - Requirements for startups, shutdowns, and malfunctions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... CATEGORIES National Emission Standards for Coke Oven Batteries § 63.310 Requirements for startups, shutdowns... or operator shall operate and maintain the coke oven battery and its pollution control equipment... operator of a coke oven battery shall develop, according to paragraph (c) of this section, a...

  12. Start-up and inhibition analysis of the Anammox process seeded with anaerobic granular sludge.

    PubMed

    Tang, Chong-jian; Zheng, Ping; Mahmood, Qaisar; Chen, Jian-wei

    2009-08-01

    The longer start-up period of the Anammox process is due to the very low cellular yield and growth rates of Anammox bacteria. Nitrite inhibition is considered to be the key factor in the instability of the Anammox process during the operation. However, little attention was paid to the inhibitory effect of pH and free ammonia. This paper presents start-up and inhibition analysis of an Anammox biofilm reactor seeded with anaerobic granular sludge. Results showed that the start-up period could be divided into the sludge lysis phase, lag phase, propagation phase, stationary phase and inhibition phase. Optimization control could be implemented correspondingly to accelerate the start-up of Anammox bioreactors. Effluent pH increased to 8.7-9.1 when the nitrogen removal rate was higher than 1,200 mg l(-1) day(-1). The free ammonia concentration was accompanied with a higher level of 64-73 mg l(-1). Inhibitory effects of high pH and free ammonia on Anammox bacteria contributed to the destabilization of the Anammox bioreactor during the first 125 days with influent KHCO(3) of 0.5 g l(-1). Increasing the suffering capacity in the inlet by dosing 1.25 g KHCO(3) l(-1) effectively reduced the pH variation, and the nitrogen removal performance of the reactor was further developed.

  13. Public Data Set: Impedance of an Intense Plasma-Cathode Electron Source for Tokamak Plasma Startup

    DOE Data Explorer

    Hinson, Edward T. [University of Wisconsin-Madison] (ORCID:000000019713140X); Barr, Jayson L. [University of Wisconsin-Madison] (ORCID:0000000177685931); Bongard, Michael W. [University of Wisconsin-Madison] (ORCID:0000000231609746); Burke, Marcus G. [University of Wisconsin-Madison] (ORCID:0000000176193724); Fonck, Raymond J. [University of Wisconsin-Madison] (ORCID:0000000294386762); Perry, Justin M. [University of Wisconsin-Madison] (ORCID:0000000171228609)

    2016-05-31

    This data set contains openly-documented, machine readable digital research data corresponding to figures published in E.T. Hinson et al., 'Impedance of an Intense Plasma-Cathode Electron Source for Tokamak Plasma Startup,' Physics of Plasmas 23, 052515 (2016).

  14. 40 CFR 65.6 - Startup, shutdown, and malfunction plan and procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... sources referenced from 40 CFR part 63, subpart F, by the compliance date specified in that subpart. The... 40 Protection of Environment 16 2014-07-01 2014-07-01 false Startup, shutdown, and malfunction plan and procedures. 65.6 Section 65.6 Protection of Environment ENVIRONMENTAL PROTECTION...

  15. Startup and control of out-of-core thermionic space reactors

    NASA Astrophysics Data System (ADS)

    Houts, M. G.; Lanning, D. D.

    An analysis of out-of-core thermionic space reactor (OTR) startup and control has been performed. The reference ionic thermal reactor (ITR) chosen for this study is a 75 kWt version of the STAR-C (GA Technologies 1987). The applicability of point kinetics was first verified for the reference OTR system. Point kinetics applicability was verified for core length-to-diameter (L/D) ratios of two and four, and for both subcritical-to-critical and critical-to-supercritical transients. A coupled thermal/point kinetics code was then written, and OTR startup was analyzed. The analyses lead to several observations. First, point kinetics is applicable to the reference OTR for all transients considered. Second, to achieve a 900 second startup the reference OTR must operate at powers well above steady-state rated power during startup. Finally, the large thermal inertia of the radial reflector could be used to reduce radiator temperature during the first several hundred seconds of operation. Further research should be performed on transient heat pipe operation and on off-normal thermionic converter operation.

  16. 40 CFR 63.2852 - What is a startup, shutdown, and malfunction plan?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 13 2014-07-01 2014-07-01 false What is a startup, shutdown, and malfunction plan? 63.2852 Section 63.2852 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission...

  17. Experimental Labs for Start-Ups: The Role of the "Venture-Sitter"

    ERIC Educational Resources Information Center

    Matricano, Diego; Pietrobon, Alberto

    2010-01-01

    Curley and Formica's (2008, 2010) studies of high-expectation entrepreneurship focus on the role of "experimental laboratories" in promoting the start-up and successful development of high-expectation firms. Although it is not difficult to understand the potential usefulness of these experimental labs--business simulators in which skilled partners…

  18. Startup and control of out-of-core thermionic space reactors

    NASA Astrophysics Data System (ADS)

    Houts, Michael G.; Lanning, Davic D.

    1992-01-01

    An analysis of out-of-core thermionic space reactor (OTR) startup and control has been performed. The reference OTR chosen for this study is a 75 kWt version of the STAR-C (GA Technologies 1987). The applicability of point kinetics was first verified for the reference OTR system. Point kinetics applicability was verified for core length-to-diameter (L/D) ratios of two and four, and for both subcritical-to-critical and critical-to-supercritical transients. A coupled thermal/point kinetics code was then written, and OTR startup was analyzed. The analyses lead to several observations. First, point kinetics is applicable to the reference OTR for all transients considered. Second, to achieve a 900-s startup the reference OTR must operate at powers well above steady-state rated power during startup. Finally, the large thermal inertia of the radial reflector could be used to reduce radiator temperature during the first several hundred seconds of operation. Further research should be performed on transient heat pipe operation and on off-normal thermionic converter operation.

  19. First LNG from North field overcomes feed, start-up problems

    SciTech Connect

    Redha, A.; Rahman, A.; Al-Thani, N.H.; Ishikura, Masayuki; Kikkawa, Yoshitsugi

    1998-08-24

    Qatar Gas LNG is the first LNG project in the gas-development program of the world`s largest gas reservoir, North field. The LNG plant was completed within the budget and schedule. The paper discusses the LNG plant design, LNG storage and loading, alternative mercaptan removal, layout modification, information and control systems, training, data management systems, start-up, and performance testing.

  20. 77 FR 71323 - Reconsideration of Certain New Source and Startup/Shutdown Issues: National Emission Standards...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ... AGENCY 40 CFR Parts 60 and 63 RIN 2060-AR62 Reconsideration of Certain New Source and Startup/Shutdown... or in 40 CFR 63.9982. If you have any questions regarding the applicability of this action to a... representative as listed in 40 CFR 60.4 or 40 CFR 63.13 (General Provisions). B. What should I consider as...

  1. Influence of the startup instant of quench in a superconducting current limiter

    SciTech Connect

    Leveque, J.; Netter, D.; Rezzoug, A.; Caron, J.P.; Sargos, F.M.

    1996-09-01

    The influence of the startup instant of the quench in a superconducting current limiter is studied. The heat transfer equation is numerically solved, using finite difference method, and taking the effects of current sharing into account. The results show the importance of this instant on the dissipated power, the temperature-increase and on the efficiency of the current limitation.

  2. 40 CFR 65.6 - Startup, shutdown, and malfunction plan and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... sources referenced from 40 CFR part 63, subpart F, by the compliance date specified in that subpart. The... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Startup, shutdown, and malfunction plan and procedures. 65.6 Section 65.6 Protection of Environment ENVIRONMENTAL PROTECTION...

  3. International Meeting on Business Start-up (Lille, France, November 26-28, 1992).

    ERIC Educational Resources Information Center

    Melis, Africa, Ed.; Peigne, Florence, Ed.

    1992-01-01

    An international meeting explored work on business start-up undertaken jointly by CEDEFOP (European Centre for the Development of Vocational Training) and France's Agence Nationale pour la creation d'entreprise. One opening presentation (Melis) addressed the basic idea underlying the research: to identify and highlight the role of training and…

  4. 40 CFR 63.2852 - What is a startup, shutdown, and malfunction plan?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 13 2013-07-01 2012-07-01 true What is a startup, shutdown, and malfunction plan? 63.2852 Section 63.2852 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission...

  5. 40 CFR 63.2852 - What is a startup, shutdown, and malfunction plan?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 12 2011-07-01 2009-07-01 true What is a startup, shutdown, and malfunction plan? 63.2852 Section 63.2852 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES National Emission Standards...

  6. The Perfect Pairing: The Adult Learner and the Boutique Winery in the Start-Up Phase

    ERIC Educational Resources Information Center

    Heath-Simpson, Delta F.

    2011-01-01

    The purpose of this phenomenological study was to understand and describe the lived experiences of adult learners who are owners and managers of small winery businesses operating in the start-up phase of the organizational life cycle. The study explored and identified the meaning of adult learning in the entrepreneurial context and its affect on…

  7. What's New in the Launching of Start-Ups? Features and Implications of Laboratory Experiments

    ERIC Educational Resources Information Center

    Matricano, Diego

    2009-01-01

    This article responds to "Laboratory experiments as a tool in the empirical economic analysis of high-expectation start-ups" by Martin Curley and Piero Formica, published in the December 2008 issue of "Industry and Higher Education." The exploitation of knowledge and experience is increasingly important to companies operating in the globalized…

  8. Human Resource Blueprints in Irish High-Tech Start-Up Firms

    ERIC Educational Resources Information Center

    Keating, Mary A.; Olivares, Mariabrisa

    2006-01-01

    Focusing on Irish high-tech start-ups, this paper reports on the results of an empirical study of organization building by entrepreneurial firms, specifically in relation to human resource practices. The research findings are benchmarked with findings from SPEC, the Stanford Project of Emerging Companies (Baron and Hannan, 2002). Human resources…

  9. 76 FR 50887 - Elections Regarding Start-Up Expenditures, Corporation Organizational Expenditures, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-17

    ... Register (73 FR 38910). A notice of proposed rulemaking (REG-164965-04) cross- referencing the temporary regulations was published in the Federal Register (73 FR 38940) on the same day. One written comment... Internal Revenue Service 26 CFR Part 1 RIN 1545-BE77 Elections Regarding Start-Up Expenditures,...

  10. 42 CFR 137.302 - Are Federal funds available to cover start-up costs associated with initial Tribal assumption of...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Are Federal funds available to cover start-up costs... funds available to cover start-up costs associated with initial Tribal assumption of environmental responsibilities? (a) Yes, start-up costs are available as provided in section 508(c) of the Act . During...

  11. Start-up of the PCI Facility at Stelco Hilton Works

    SciTech Connect

    Hyde, J.B.; Hutchinson, S.; Brown, R.

    1996-12-31

    In the late 1980`s it became apparent that the future coke requirements for the two Blast Furnaces at Stelco`s Hilton Works would be greater than the projected internal coke production levels. The three older coke batteries had been producing for forty years and were expected to be shutdown by the mid 1990`s due to age and environmental considerations. Although the purchase of coke from external sources to supplement needs was accepted as a short term solution, it was not considered a viable long term strategy. Decreasing world coke production forecasted increasing coke purchase costs and availability constraints. Construction of a new coke battery represented a large capital investment, high operating costs, and new environmental implications. Early studies suggested pulverized coal injection was the most viable solution to the coke shortfall problem. PCI rates had advanced significantly during the 1980`s and the process continued to be a leading edge technology entering the 1990`s. To return Hilton Works to a near self sufficient coke state, a team was formed whose efforts were directed towards investigating the available PCI technologies, selecting a process which was most suitable, and arranging acceptable financing. The facility design was to be based on Kawasaki technology. Construction of the facility and injection lines to the Blast Furnaces occurred over 13 months. On Dec. 18, 1995, injection began to E Blast Furnace followed by injection to D Blast Furnace on January 16, 1996. This paper will provide a description of Hilton Works` Blast Furnaces and the PCI Facility. The start-up and current status of PCI will also be examined.

  12. Pentachlorophenol aerobic removal in a sequential reactor: start-up procedure and kinetic study.

    PubMed

    Angelucci, Domenica Mosca; Tomei, M Concetta

    2015-01-01

    This study has demonstrated the applicability of a simple technology such as the sequencing batch reactor (SBR), operated with suspended biomass, to the aerobic biodegradation of a highly toxic compound, the pentachlorophenol (PCP). An enrichment of a microbial consortium, originated from the biomass of an urban wastewater treatment plant, was performed and 70 days were sufficient to achieve removal efficiencies of ∼90% with the compound fed as only carbon and energy source Once completed the start-up period, the SBR was operated with the acclimatized biomass for 60 days at a feed concentration of PCP in the range of 10-20 mg L(-1). Improved performance was observed at increased influent concentration and the reached removal efficiency for the highest concentrations was stable at values≥90%. Kinetic and stoichiometric characterization of the acclimated biomass was performed with biodegradation tests carried out in the bioreactor during the reaction phase. The classical and a modified four-parameter forms of the Haldane equation were applied to model the substrate inhibited kinetics. Both models provided reliable predictions with high correlation coefficients (>0.99). The biomass characterization was completed with the evaluation of the growth yield coefficient, Y (0.075 on chemical oxygen demand base) and endogenous respiration rate, b (0.054 d(-1)). The aerobic SBR, operated in the metabolic mode with a mixed culture, showed superior performance in comparison to continuous systems applied in the same range of PCP influent loads and achieved removal rates are suitable for application.

  13. Start-up and steady thermal oscillation of a pulsating heat pipe

    NASA Astrophysics Data System (ADS)

    Xu, J. L.; Zhang, X. M.

    2005-06-01

    As a novel electronic cooling device, pulsating heat pipes (PHPs) have been received attention in recent years. However, literature survey shows that no studies were carried out on the start-up and steady thermal oscillation of the PHPs. In the present paper, the copper capillary tube was being bended to form the snake-shaped PHP. Heating power was applied on the heating section, and transferred to the condensation section and dissipated to the environment by the pure natural convection. The inside diameter of the capillary tube is 2.0 mm and the working fluid is selected as FC-72. A high speed data acquisition system was used to detect the start-up and steady thermal oscillation of the PHP. Two types of the start-up process were observed: a sensible heat receiving start-up process accompanying an apparent temperature overshoot followed by the steady thermal oscillation at low heating power, and a smooth sensible heat receiving start-up process incorporating a smooth oscillation period at high heating power. For the steady thermal oscillation, also two types were found: the random thermal oscillation with a wide frequency range, indicating the random distribution of the vapor plug and liquid slug inside the capillary tube at low heating power, and the quasi periodic thermal oscillation with the same characteristic frequency for both heating section and condensation section, indicating the uniform distribution of the vapor plug and liquid slug inside the capillary tube at high heating power. The power spectral density (PSD) was used to analyze the thermal oscillation waves. The frequency corresponds to the time that a couple of adjacent vapor plug and liquid slug passing through a specific wall surface.

  14. The real world and lunar base activation scenarios

    NASA Technical Reports Server (NTRS)

    Schmitt, Harrison H.

    1992-01-01

    A lunar base or a network of lunar bases may have highly desirable support functions in a national or international program to explore and settle Mars. In addition, He-3 exported from the Moon could be the basis for providing much of the energy needs of humankind in the twenty-first century. Both technical and managerial issues must be addressed when considering the establishment of a lunar base that can serve the needs of human civilization in space. Many of the technical issues become evident in the consideration of hypothetical scenarios for the activation of a network of lunar bases. Specific and realistic assumptions must be made about the conduct of various types of activities in addition to the general assumptions given above. These activities include landings, crew consumables, power production, crew selection, risk management, habitation, science station placement, base planning, science, agriculture, resource evaluation, readaptation, plant activation and test, storage module landings, resource transport module landings, integrated operations, maintenance, Base 2 activation, and management. The development of scenarios for the activation of a lunar base or network of bases will require close attention to the 'real world' of space operations. That world is defined by the natural environment, available technology, realistic objectives, and common sense.

  15. Applying activity-based costing in long-term care.

    PubMed

    Wodchis, W P

    1998-01-01

    As greater numbers of the elderly use health services, and as health care costs climb, effective financial tracking is essential. Cost management in health care can benefit if costs are linked to the care activities where they are incurred. Activity-based costing (ABC) provides a useful approach. The framework aligns costs (inputs), through activities (process), to outputs and outcomes. It allocates costs based on client care needs rather than management structure. The ABC framework was tested in a residential care facility and in supportive housing apartments. The results demonstrate the feasibility and advantages of ABC for long term care agencies, including community-based care. PMID:10339203

  16. Applying activity-based costing in long-term care.

    PubMed

    Wodchis, W P

    1998-01-01

    As greater numbers of the elderly use health services, and as health care costs climb, effective financial tracking is essential. Cost management in health care can benefit if costs are linked to the care activities where they are incurred. Activity-based costing (ABC) provides a useful approach. The framework aligns costs (inputs), through activities (process), to outputs and outcomes. It allocates costs based on client care needs rather than management structure. The ABC framework was tested in a residential care facility and in supportive housing apartments. The results demonstrate the feasibility and advantages of ABC for long term care agencies, including community-based care.

  17. Learning Outcomes of Project-Based and Inquiry-Based Learning Activities

    ERIC Educational Resources Information Center

    Panasan, Mookdaporn; Nuangchalerm, Prasart

    2010-01-01

    Problem statement: Organization of science learning activities is necessary to rely on various methods of organization of learning and to be appropriate to learners. Organization of project-based learning activities and inquiry-based learning activities are teaching methods which can help students understand scientific knowledge. It would be more…

  18. Hands-On Science: Science Start-ups.

    ERIC Educational Resources Information Center

    Kepler, Lynne

    1992-01-01

    Article discusses the four elements of good elementary science programs and offers ideas for creative hands-on science and across-the-curriculum activities (e.g., a please touch science center, curriculum planning chart, and getting to know you water activity). It notes science-related events and describes four science reference books. (SM)

  19. Startup of the New 200 West Pump-and-Treat, Hanford Site, Richland, Washington - 13214

    SciTech Connect

    Byrnes, Mark E.; Simmons, Sally; Morse, John

    2013-07-01

    resin (which has been proven effective in removing Tc-99). The water is then transferred to the biological treatment building for further treatment. When the lead vessel in each of the two treatment trains becomes fully loaded with Tc-99, the Purolite A530E resin is transferred to a separate tank where it is heated to 160 deg. F to remove volatile organics prior to disposal at the Environmental Restoration Disposal Facility. The biological treatment building has a maximum flow capacity of 2,500 gpm. Groundwater from the nonradiological extraction wells and treated groundwater from the RAD building are initially pumped into an equalization tank and then into two parallel fluidized bed reactors (FBRs). The FBRs contain granulated activated carbon in suspension for microbes to populate, a carbon-based food source for the microbes to eat (e.g., MicroCg{sup TM}, molasses, or sodium lactate), and nitrate for the microbes to breathe (represents 'anoxic' conditions that contain little or no dissolved oxygen). The FBRs are maintained at a temperature between 55 deg. F and 90 deg. F, and at a pH between 6.5 and 6.8, to maximize microbial growth. The FBRs break down the nitrate, reduce the hexavalent chromium to trivalent chromium, and break down a good portion of the carbon tetrachloride and TCE. From the FBRs, groundwater is pumped through a carbon separation tank, then through a splitter box that divides the water evenly between four membrane bioreactors (MBRs) that further break down the contaminants. The MBRs have aeration capacity to provide sufficient oxygen for maintaining the aerobic biological process. The MBRs use submerged membranes for filtration. Vertically strung fibers are found in the membrane zone where a vacuum draws water through tiny pores in the fibers. The liquid is then pumped to air strippers to remove any volatile organics that have passed through the bioreactors. Solids from the MBRs are pumped to rotary drum thickeners and centrifuges for dewatering

  20. Antitrypanosomal activity of 5-nitro-2-aminothiazole-based compounds.

    PubMed

    Papadopoulou, Maria V; Bloomer, William D; Rosenzweig, Howard S; Wilkinson, Shane R; Szular, Joanna; Kaiser, Marcel

    2016-07-19

    A small series of 5-nitro-2-aminothiazole-based amides containing arylpiperazine-, biphenyl- or aryloxyphenyl groups in their core were synthesized and evaluated as antitrypanosomatid agents. All tested compounds were active or moderately active against Trypanosoma cruzi amastigotes in infected L6 cells and Trypanosoma brucei brucei, four of eleven compounds were moderately active against Leishmania donovani axenic parasites while none were deemed active against T. brucei rhodesiense. For the most active/moderately active compounds a moderate selectivity against each parasite was observed. There was good correlation between lipophilicity (clogP value) and antileishmanial activity or toxicity against L6 cells. Similarly, good correlation existed between clogP values and IC50 values against T. cruzi in structurally related subgroups of compounds. Three compounds were more potent as antichagasic agents than benznidazole but were not activated by the type I nitrorectusase (NTR). PMID:27092415

  1. Activity-Based Costing Systems for Higher Education.

    ERIC Educational Resources Information Center

    Day, Dennis H.

    1993-01-01

    Examines traditional costing models utilized in higher education and pinpoints shortcomings related to proper identification of costs. Describes activity-based costing systems as a superior alternative for cost identification, measurement, and allocation. (MLF)

  2. 24 CFR 92.257 - Faith-based activities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Development HOME INVESTMENT PARTNERSHIPS PROGRAM Project Requirements § 92.257 Faith-based activities. (a... CFR parts 84 and 85). (f) If a state or local government voluntarily contributes its own funds...

  3. 24 CFR 92.257 - Faith-based activities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Development HOME INVESTMENT PARTNERSHIPS PROGRAM Project Requirements § 92.257 Faith-based activities. (a... CFR parts 84 and 85). (f) If a state or local government voluntarily contributes its own funds...

  4. Activity-based costing saves on supply distribution costs.

    PubMed

    1997-10-01

    Activity-based costing is coming, but is your organization ready? A few pioneering hospitals are already reaping the operational and economic benefits of activity-based costing in their materials management, and now the VHA purchasing alliance is offering this costing option to its 1,200 hospital members. The concept is simple, so why aren't there more takers? Here are the details on this pragmatic pricing approach that could save your facility plenty.

  5. PTTC upgrades from startup to full speed ahead

    SciTech Connect

    Rowell, D.

    1995-12-01

    This report describes technology transfer activities of the Petroleum Technology Transfer Council (PTTC) in it`s first year as a national non-profit clearing house for technology transfer to domestic producers.

  6. Activity-Based Intervention Practices in Special Education

    ERIC Educational Resources Information Center

    Ozen, Arzu; Ergenekon, Yasemin

    2011-01-01

    Teaching practices in natural settings such as activity-based intervention (ABI) are suggested as alternatives to be used in effective early childhood education. As a multidisciplinary model, ABI consists of four components, which are choosing activities according to the child's interests; teaching generalizable goals embedded in routines and…

  7. Comprehensive School-Based Physical Activity Promotion: A Review

    ERIC Educational Resources Information Center

    Erwin, Heather; Beighle, Aaron; Carson, Russell L.; Castelli, Darla M.

    2013-01-01

    Physical activity (PA) participation levels among youth remain well below national recommendations. Thus, a variety of strategies to promote youth PA have been advocated, including multifaceted, school-based approaches. One identified as having great potential is a comprehensive school physical activity program (CSPAP). The goal of a CSPAP is to…

  8. Potentiometric Acid-Base Titrations with Activated Graphite Electrodes

    NASA Astrophysics Data System (ADS)

    Riyazuddin, P.; Devika, D.

    1997-10-01

    Dry cell graphite (DCG) electrodes activated with potassium permanganate are employed as potentiometric indicator electrodes for acid-base titrations. Special attention is given to an indicator probe comprising activated DCG-non-activiated DCG electrode couple. This combination also proves suitable for the titration of strong or weak acids.

  9. Network-Based Business Simulation Activities in Technical Professional Education

    ERIC Educational Resources Information Center

    Vescoukis, Vassilios C.; Retalis, Symeon; Anagnostopoulos, Dimosthenis

    2003-01-01

    For a long time on-the-job training has been considered as the single point of contact of technical education with the real world job market. Indeed, traditional on-the-job training activities are of great educational value and complement uniquely any classroom-based learning activity. However, it has been observed that several obstacles arise…

  10. Project-Based Language Learning: An Activity Theory Analysis

    ERIC Educational Resources Information Center

    Gibbes, Marina; Carson, Lorna

    2014-01-01

    This paper reports on an investigation of project-based language learning (PBLL) in a university language programme. Learner reflections of project work were analysed through Activity Theory, where tool-mediated activity is understood as the central unit of analysis for human interaction. Data were categorised according to the components of human…

  11. Activity-Based Costing: A Cost Management Tool.

    ERIC Educational Resources Information Center

    Turk, Frederick J.

    1993-01-01

    In college and university administration, overhead costs are often charged to programs indiscriminately, whereas the support activities that underlie those costs remain unanalyzed. It is time for institutions to decrease ineffective use of resources. Activity-based management attributes costs more accurately and can improve efficiency. (MSE)

  12. Fabric-based integrated energy devices for wearable activity monitors.

    PubMed

    Jung, Sungmook; Lee, Jongsu; Hyeon, Taeghwan; Lee, Minbaek; Kim, Dae-Hyeong

    2014-09-01

    A wearable fabric-based integrated power-supply system that generates energy triboelectrically using human activity and stores the generated energy in an integrated supercapacitor is developed. This system can be utilized as either a self-powered activity monitor or as a power supply for external wearable sensors. These demonstrations give new insights for the research of wearable electronics. PMID:25070873

  13. Digital computer study of nuclear reactor thermal transients during startup of 60-kWe Brayton power conversion system

    NASA Technical Reports Server (NTRS)

    Jefferies, K. S.; Tew, R. C.

    1974-01-01

    A digital computer study was made of reactor thermal transients during startup of the Brayton power conversion loop of a 60-kWe reactor Brayton power system. A startup procedure requiring the least Brayton system complication was tried first; this procedure caused violations of design limits on key reactor variables. Several modifications of this procedure were then found which caused no design limit violations. These modifications involved: (1) using a slower rate of increase in gas flow; (2) increasing the initial reactor power level to make the reactor respond faster; and (3) appropriate reactor control drum manipulation during the startup transient.

  14. A New Activity-Based Financial Cost Management Method

    NASA Astrophysics Data System (ADS)

    Qingge, Zhang

    The standard activity-based financial cost management model is a new model of financial cost management, which is on the basis of the standard cost system and the activity-based cost and integrates the advantages of the two. It is a new model of financial cost management with more accurate and more adequate cost information by taking the R&D expenses as the accounting starting point and after-sale service expenses as the terminal point and covering the whole producing and operating process and the whole activities chain and value chain aiming at serving the internal management and decision.

  15. High activity iodine 125 endocurietherapy for recurrent skull base tumors

    SciTech Connect

    Kumar, P.P.; Good, R.R.; Leibrock, L.G.; Mawk, J.R.; Yonkers, A.J.; Ogren, F.P.

    1988-04-15

    Experience with endocurietherapy of skull base tumors is reviewed. We present our cases of recurrent pituitary hemangiopericytoma, radiation-induced recurrent meningioma, recurrent clival chordoma, recurrent nasopharyngeal cancer involving the cavernous sinus, and recurrent parotid carcinoma of the skull base which were all successfully retreated with high-activity 125-iodine (I-125) permanent implantation.76 references.

  16. An Active Learning Exercise for Introducing Agent-Based Modeling

    ERIC Educational Resources Information Center

    Pinder, Jonathan P.

    2013-01-01

    Recent developments in agent-based modeling as a method of systems analysis and optimization indicate that students in business analytics need an introduction to the terminology, concepts, and framework of agent-based modeling. This article presents an active learning exercise for MBA students in business analytics that demonstrates agent-based…

  17. Lunar bases and space activities of the 21st century

    SciTech Connect

    Mendell, W.W.

    1985-01-01

    The present conference gives attention to such major aspects of lunar colonization as lunar base concepts, lunar transportation, lunar science research activities, moon-based astronomical researches, lunar architectural construction, lunar materials and processes, lunar oxygen production, life support and health maintenance in lunar bases, societal aspects of lunar colonization, and the prospects for Mars colonization. Specific discussions are presented concerning the role of nuclear energy in lunar development, achromatic trajectories and the industrial scale transport of lunar resources, advanced geologic exploration from a lunar base, geophysical investigations of the moon, moon-based astronomical interferometry, the irradiation of the moon by particles, cement-based composites for lunar base construction, electrostatic concentration of lunar soil minerals, microwave processing of lunar materials, a parametric analysis of lunar oxygen production, hydrogen from lunar regolith fines, metabolic support for a lunar base, past and future Soviet lunar exploration, and the use of the moons of Mars as sources of water for lunar bases.

  18. Active Oxidation of a UHTC-Based CMC

    NASA Technical Reports Server (NTRS)

    Glass, David E.; Splinter, Scott C.

    2012-01-01

    The active oxidation of ceramic matrix composites (CMC) is a severe problem that must be avoided for multi-use hypersonic vehicles. Much work has been performed studying the active oxidation of silicon-based CMCs such as C/SiC and SiC-coated carbon/carbon (C/C). Ultra high temperature ceramics (UTHC) have been proposed as a possible material solution for high-temperature applications on hypersonic vehicles. However, little work has been performed studying the active oxidation of UHTCs. The intent of this paper is to present test data indicating an active oxidation process for a UHTC-based CMC similar to the active oxidation observed with Si-based CMCs. A UHTC-based CMC was tested in the HyMETS arc-jet facility (or plasma wind tunnel, PWT) at NASA Langley Research Center, Hampton, VA. The coupon was tested at a nominal surface temperature of 3000 F (1650 C), with a stagnation pressure of 0.026 atm. A sudden and large increase in surface temperature was noticed with negligible increase in the heat flux, indicative of the onset of active oxidation. It is shown that the surface conditions, both temperature and pressure, fall within the region for a passive to active transition (PAT) of the oxidation.

  19. Active media for tunable lasers based on hybrid polymers

    SciTech Connect

    Kopylova, T N; Eremina, N S; Vaitulevich, E A; Samsonova, L G; Maier, G V; Tel'minov, E N; Solodova, T A; Solodov, A M

    2008-02-28

    The lasing properties of rhodamine 6G (chloride and perchlorate) in synthesised hybrid polymers based on an organic polymer (methyl methacrylate with hydroxyethyl methacrylate) and an inorganic precursor (tetraethoxysilane) are studied. Rhodamine 6G samples were transversely pumped by the second harmonic of a Nd{sup 3+}:YAG laser. It is found that the active media based on hybrid polymers have a considerably longer service life compared to the active media based on organic polymers. The structure of the hybrid polymer is studied by the methods of IR Fourier spectroscopy, X-ray diffraction, and thermogravimetry. It is shown that the longer service life of hybrid-polymer active media is explained by the formation of an inorganic nanostructure network in them, which improves the thermooptic properties of the material and reduces the efficiency of thermal decomposition of active molecules. (lasers. amplifiers)

  20. Grain-based activated carbons for natural gas storage.

    PubMed

    Zhang, Tengyan; Walawender, Walter P; Fan, L T

    2010-03-01

    Natural gas has emerged as a potential alternative to gasoline due to the increase in global energy demand and environmental concerns. An investigation was undertaken to explore the technical feasibility of implementing the adsorbed natural gas (ANG) storage in the fuel tanks of motor vehicles with activated carbons from biomass, e.g., sorghum and wheat. The grain-based activated carbons were prepared by chemical activation; the experimental parameters were varied to identify the optimum conditions. The porosity of the resultant activated carbons was evaluated through nitrogen adsorption; and the storage capacity, through methane adsorption. A comparative study was also carried out with commercial activated carbons from charcoal. The highest storage factor attained was 89 for compacted grain-based activated carbons from grain sorghum with a bulk density of 0.65 g/cm(3), and the highest storage factor attained is 106 for compacted commercial activated carbons (Calgon) with a bulk density of 0.70 g/cm(3). The storage factor was found to increase approximately linearly with increasing bulk density and to be independent of the extent of compaction. This implies that the grain-based activated carbons are the ideal candidates for the ANG storage.

  1. Uses of motion imagery in activity-based intelligence

    NASA Astrophysics Data System (ADS)

    Lash, Thomas D.

    2013-05-01

    Activity-Based Intelligence (ABI) was defined by the Office of the Undersecretary of Defense for Intelligence as "a discipline of intelligence where the analysis and subsequent collection is focused on activity and transactions associated with an entity, population, or area of interest." ABI is inherently multi-INT, and motion imagery is a rich data source for ABI analysis. Motion imagery provides a unique temporal aspect which is critical for activity detection and classification. Additionally, motion imagery tends to have high spatial oversampling useful for determining activities and patterns above the noise threshold.

  2. Shot noise startup of the 6 NM SASE FEL at the Tesla Test Facility

    SciTech Connect

    Pierini, P.; Fawley, W.M.

    1995-12-31

    We present here an analysis of the shot noise startup of the 6 nm SASE FEI proposal at the TESLA Test Facility in DESY The statistical of the saturation length and output power due to the intrinsic randomness of the noise startup are investigated with the use of the 2D time dependent code GINGER, that takes into account propagation effects and models shot noise. We then provide estimates for the spectral contents and linewidth of the emitted radiation and describe its spiking characteristics. The output radiation will develop superradiant spikes seeded by the shot noise in the electron beam, which can entrance the average emitted power at the expense of some spectral broadening.

  3. Analysis of start-up transient for a powertrain system with a nonlinear clutch damper

    NASA Astrophysics Data System (ADS)

    Li, Laihang; Singh, Rajendra

    2015-10-01

    The transient vibration phenomenon in a vehicle powertrain system during the start-up (or shut-down) process is studied with a focus on the nonlinear characteristics of a multi-staged clutch damper. First, a four-degree-of-freedom torsional model with multiple discontinuous nonlinearities under flywheel motion input is developed, and the powertrain transient event is validated with a vehicle start-up experiment. Second, the role of the nonlinear torsional path on the transient event is investigated in the time and time-frequency domains; interactions between the clutch damper and the transmission transients are estimated by using two metrics. Third, the harmonic balance method is applied to examine the nonlinear characteristics of clutch damper during a slowly varying non-stationary process in a simplified and validated single-degree-of-freedom powertrain system model. Finally, analytical formulas are successfully developed and verified to approximate the nonlinear amplification level for a rapidly varying process.

  4. Methanogenic population dynamics during start-up of anaerobic digesters treating municipal solid waste and biosolids

    SciTech Connect

    Griffin, M.E.; McMahon, K.D.; Mackie, R.I.; Raskin, L.

    1998-02-05

    An aggressive start-up strategy was used to initiate codigestion in two anaerobic, continuously mixed bench-top reactors at mesophilic (37 C) and thermophilic (55 C) conditions. The digesters were inoculated with mesophilic anaerobic sewage sludge and cattle manure and were fed a mixture of simulated municipal solid waste and biosolids in proportions that reflect US production rates. The design organic loading rate was 3.1 kg volatile solids/m{sup 3}/day and the retention time was 20 days. Ribosomal RNA-targeted oligonucleotide probes were used to determine the methanogenic community structure in the inocula and the digesters. Chemical analyses were performed to evaluate digester performance. The aggressive start-up strategy was successful for the thermophilic reactor, despite the use of a mesophilic inoculum.

  5. Lessons learned from start-up testing of a mixed waste incinerator

    SciTech Connect

    Holmes Burns, H.; Burns, D.B.

    1997-05-01

    Start-up testing of a new mixed waste incinerator, the Consolidated Incineration Facility (CIF), has been completed at the Department of Energy`s Savannah River Site (SRS). The incinerator is equipped with an air pollution control system (APCS) that includes a wet quench and scrubber followed by dry air filtration using high efficiency particulate air (HEPA) filters. The system was designed with optimum materials to maximize reliability, runtime, and ease of maintenance. Changes to the CIF operation and materials have been made to maximize system performance and minimize corrosion. This paper presents a brief overview of the incinerator design philosophy, pilot-scale testing results, and some of the lessons learned during the start-up testing of the CIF.

  6. Use of ICRH for startup and initial heating of the TMX-U central cell

    SciTech Connect

    Molvik, A.W.; Falabella, S.

    1982-05-01

    Ion cyclotron resonance heating (ICRH) was evaluated and it was found to be satisfactory for use in establishing the conditions necessary to form a thermal barrier in TMX-upgrade (TMX-U). We discuss the constraints that must be satisfied in order to maintain a plasma, and outline a complete startup scenario that ends with the plasma at design parameters. The detailed discussions in this report concentrate on those parts of startup where ICRH is necessary. The ability of ICRH to couple power into a plasma at the fundamental ion cyclotron resonance, w/sub ci/, is determined from experiments with a half-turn loop antenna in the Phaedrus tandem mirror central cell. From these experiments, we get the empirical scaling that shows power deposited in the plasma is proportional to the plasma density.

  7. System startup simulation for an in-core thermionic reactor with heat pipe cooling

    NASA Astrophysics Data System (ADS)

    Determan, William R.; Otting, William D.

    1992-01-01

    The heat pipe cooled thermionic (HPTI) reactor relies on in-core sodium heat pipes to provide a redundant means of cooling the 72 thermionic fuel elements (TFEs) which comprise the 40-kWe reactor core assembly. In-core heat pipe cooling was selected for the reactor design due to a requirement for multiple system on-orbit restarts over its lifetime. Powering up the reactor requires the in-core and radiator heat pipes to undergo a thaw cycle with a rapid ascension in power to their operating temperatures. The present study considers how fast the thaw-out and power ascension cycle can be safely accomplished within a reactor core. As part of the study, a transient startup simulator model of the heat pipe cooled reactor system was developed. Results of the startup transient simulation are provided.

  8. Solid oxide fuel cell power plant having a bootstrap start-up system

    DOEpatents

    Lines, Michael T

    2016-10-04

    The bootstrap start-up system (42) achieves an efficient start-up of the power plant (10) that minimizes formation of soot within a reformed hydrogen rich fuel. A burner (48) receives un-reformed fuel directly from the fuel supply (30) and combusts the fuel to heat cathode air which then heats an electrolyte (24) within the fuel cell (12). A dilute hydrogen forming gas (68) cycles through a sealed heat-cycling loop (66) to transfer heat and generated steam from an anode side (32) of the electrolyte (24) through fuel processing system (36) components (38, 40) and back to an anode flow field (26) until fuel processing system components (38, 40) achieve predetermined optimal temperatures and steam content. Then, the heat-cycling loop (66) is unsealed and the un-reformed fuel is admitted into the fuel processing system (36) and anode flow (26) field to commence ordinary operation of the power plant (10).

  9. Solvent pre-wetting as an effective start-up method for point-of-use filter

    NASA Astrophysics Data System (ADS)

    Umeda, Toru; Sugiyama, Shinichi; Nakamura, Takashi; Momota, Makoto; Sevegney, Michael; Tsuzuki, Shuichi; Numaguchi, Toru

    2012-03-01

    An effective filter start-up method has been required by device manufacturers, mainly in order to reduce waste volume of lithography process chemicals, which become more expensive as lithography technology advances. Remaining air was monitored during static-pressure-driven filter start-up. As a result, 3500 ml of the resist was needed to eliminate remaining air. For improvement, cyclohexanone pre-wetting was applied prior to the resist introduction. As a result, the resist volume needed for the solvent displacement was 1900 ml, approximately half the volume required for staticpressure- driven start-up. Other solvents were evaluated for the pre-wetting start-up method. Results, in descending order of performance were PGME (best) < PGMEA = IPA < cyclohexanone (worst). Moreover, air displacement performance strongly correlated with Hansen solubility parameter distance between each solvent and nylon 6,6 material.

  10. DR JOHN ADAMCZYK AND DR LONNIE REID EXAMINE SOFTWARE FOR THE NEW START-UP SOFTWARE - ELECTRONICS - A

    NASA Technical Reports Server (NTRS)

    1999-01-01

    DR JOHN ADAMCZYK AND DR LONNIE REID EXAMINE SOFTWARE FOR THE NEW START-UP SOFTWARE - ELECTRONICS - AND COMMUNICATIONS - SEC - INCUBATOR OPENED MAY 1 1999 AS PART OF THE LEWIS INCUBATOR FOR TECHNOLOGY - LIFT

  11. Questions abound as start-up nears for physician data bank.

    PubMed

    Gardner, E; Wagner, L; Burda, D

    1990-07-01

    The start-up of the National Practitioner Data Bank is only weeks away, but hospitals and physicians still are raising questions about the system's pros and cons. While most laud the data bank's original mission--to prevent practitioners from concealing a history of incompetence--many physicians claim the scope of the system has grown too big and fear abuse of the information.

  12. Preheating of fluid in a supercritical Brayton cycle power generation system at cold startup

    DOEpatents

    Wright, Steven A.; Fuller, Robert L.

    2016-07-12

    Various technologies pertaining to causing fluid in a supercritical Brayton cycle power generation system to flow in a desired direction at cold startup of the system are described herein. A sensor is positioned at an inlet of a turbine, wherein the sensor is configured to output sensed temperatures of fluid at the inlet of the turbine. If the sensed temperature surpasses a predefined threshold, at least one operating parameter of the power generation system is altered.

  13. Modeling of rf-assisted helicity injection start-up and current drive

    SciTech Connect

    Hwang, Y.S.; Ono, M. )

    1994-10-15

    DC-helicity injection has been successfully applied to the tokamak start-up on CDX-U and CCT tokamaks. Furthermore, CDX-U achieved plasma current levels of up to 10 kA from zero without any ohmic drive. Helicity balance and scaling from CDX-U experiments indicate that plasma current scales with the electron temperature as [ital T][sub [ital e

  14. Partnering with the NIH: Now part of the “Value Proposition” for start-ups

    PubMed Central

    Ferguson, Steven M.

    2012-01-01

    With its “value proposition” statement a start-up company needs to convince potential investors or pharma partners how it will add more value or solve a problem better than others. High value, low cost assets such as those from the NIH ranging from technology to funding to assistance provide such biomedical firms an excellent jump-start in reaching their goals. PMID:23476116

  15. Checkout and start-up of the integrated DWPF (Defense Waste Processing Facility) melter system

    SciTech Connect

    Smith, M.E.; Hutson, N.D.; Miller, D.H.; Morrison, J.; Shah, H.; Shuford, J.A.; Glascock, J.; Wurzinger, F.H.; Zamecnik, J.R.

    1989-11-11

    The Integrated DWPF Melter System (IDMS) is a one-ninth-scale demonstration of the Defense Waste Processing Facility (DWPF) feed preparation, melter, and off-gas systems. The IDMS will be the first engineering-scale melter system at SRL to process mercury and flowsheet levels of halides and sulfates. This report includes a summary of the IDMS program objectives, system and equipment descriptions, and detailed discussions of the system checkout and start-up. 10 refs., 44 figs., 20 tabs.

  16. NTN Swiss Biotech - A Look at Support Measures for Dynamic Start-ups.

    PubMed

    Heinzelmann, Elsbeth

    2016-01-01

    The Swiss biotech landscape seems to be on a healthy footing: There are many imaginative start-ups, we have first-class hospitals, highly advanced clinical research and the availability of a great deal of capital. But we have no reason to rest on our laurels as countries like the USA lead the field. We must lay down the tracks today to remain an attractive country and maintain our ranking among the 10 best locations. PMID:26931231

  17. NTN Swiss Biotech - A Look at Support Measures for Dynamic Start-ups.

    PubMed

    Heinzelmann, Elsbeth

    2016-01-01

    The Swiss biotech landscape seems to be on a healthy footing: There are many imaginative start-ups, we have first-class hospitals, highly advanced clinical research and the availability of a great deal of capital. But we have no reason to rest on our laurels as countries like the USA lead the field. We must lay down the tracks today to remain an attractive country and maintain our ranking among the 10 best locations.

  18. E-Activities: Internet-based Activities To Expand Your History Curriculum.

    ERIC Educational Resources Information Center

    Trumbauer, Lisa

    2002-01-01

    Presents three Internet-based activities for teaching elementary students about the Underground Railroad. The activities include creating a freight-train of facts about the Underground Railroad, mapping the routes of the Underground Railroad, and participating in an electronic simulation of life as a fugitive slave. (SM)

  19. Graduating into Start-up: Exploring the Transition

    ERIC Educational Resources Information Center

    Nabi, Ghulam; Holden, Rick; Walmsley, Andreas

    2009-01-01

    The main purpose of the exploratory research discussed in this paper was to generate insights into the complexity of the career-making processes involved in the transition from being a student to starting up a business. Using story-telling interviews, data were collected from fifteen graduates based in the Yorkshire region of the UK. Qualitative…

  20. Entrepreneurism from the ground up: Entrepreneurism, innovation, and responsiveness in a start-up university

    NASA Astrophysics Data System (ADS)

    Wong, Michael Paul Anthony

    Colleges and universities are under increased pressure from internal and external constituencies for increased innovation and responsiveness. Entrepreneurial private industry models such as start-up businesses, corporate ventures and spin-off organizations have been recognized for their ability to quickly adapt to changing business environments and rapidly innovate to take advantage of new opportunities. This case study investigates these claims with regard to a start-up university founded with the identity of an entrepreneurial, interdisciplinary institution that prepares graduate level students for leadership careers as entrepreneurs in the bio-tech industry. By interviewing twenty-four administrators, faculty, and members of the Board of Trustees, including all but one of the founding full-time faculty, I present an "insider's" depiction of the lived experience of those most closely associated with the founding and subsequent institution building of this unique higher education organization. Initial chapters present a theory of higher education organizations, derived from Birnbaum (1988) and Bolman and Deal (1991), as driven by two primary tasks: resolving identity and establishing power and resources in relation to that identity. I also present Russell and Russell's (1992) theory of "entrepreneurial posture" in relation to a higher education organization. Subsequent chapters analyze the start-up university's environment, strategy, culture, and structure within the framework of the two primary organizational tasks and Russell and Russell's (1992) definition of an entrepreneurial organization.

  1. Time-Frequency Analysis of Rocket Nozzle Wall Pressures During Start-up Transients

    NASA Technical Reports Server (NTRS)

    Baars, Woutijn J.; Tinney, Charles E.; Ruf, Joseph H.

    2011-01-01

    Surveys of the fluctuating wall pressure were conducted on a sub-scale, thrust- optimized parabolic nozzle in order to develop a physical intuition for its Fourier-azimuthal mode behavior during fixed and transient start-up conditions. These unsteady signatures are driven by shock wave turbulent boundary layer interactions which depend on the nozzle pressure ratio and nozzle geometry. The focus however, is on the degree of similarity between the spectral footprints of these modes obtained from transient start-ups as opposed to a sequence of fixed nozzle pressure ratio conditions. For the latter, statistically converged spectra are computed using conventional Fourier analyses techniques, whereas the former are investigated by way of time-frequency analysis. The findings suggest that at low nozzle pressure ratios -- where the flow resides in a Free Shock Separation state -- strong spectral similarities occur between fixed and transient conditions. Conversely, at higher nozzle pressure ratios -- where the flow resides in Restricted Shock Separation -- stark differences are observed between the fixed and transient conditions and depends greatly on the ramping rate of the transient period. And so, it appears that an understanding of the dynamics during transient start-up conditions cannot be furnished by a way of fixed flow analysis.

  2. Biofilter treatment of volatile organic compound emissions from reformulated paint: complex mixtures, intermittent operation, and startup.

    PubMed

    Moe, William M; Qi, Bing

    2005-07-01

    Two biofilters were operated to treat a waste gas stream intended to simulate off-gases generated during the manufacture of reformulated paint. The model waste gas stream consisted of a five-component solvent mixture containing acetone (450 ppm(v)), methyl ethyl ketone (12 ppm(v)), toluene (29 ppm(v)), ethylbenzene (10 ppm(v)), and p-xylene (10 ppm(v)). The two biofilters, identical in construction and packed with a polyurethane foam support medium, were inoculated with an enrichment culture derived from compost and then subjected to different loading conditions during the startup phase of operation. One biofilter was subjected to intermittent loading conditions with contaminants supplied only 8 hr/day to simulate loading conditions expected at facilities where manufacturing operations are discontinuous. The other biofilter was subjected to continuous contaminant loading during the initial start period, and then was switched to intermittent loading conditions. Experimental results demonstrate that both startup strategies can ultimately achieve high contaminant removal efficiency (>99%) at a target contaminant mass loading rate of 80.3 g m(-3) hr(-1) and an empty bed residence time of 59 sec. The biofilter subjected to intermittent loading conditions at startup, however, took considerably longer to reach high performance. In both biofilters, ketone components (acetone and methyl ethyl ketone) were, more rapidly degraded than aromatic hydrocarbons (toluene, ethylbenzene, and p-xylene). Scanning electron microscopy and plate count data revealed that fungi, as well as bacteria, populated the biofilters. PMID:16111134

  3. Modeling of rf-assisted helicity injection start-up and current drive

    NASA Astrophysics Data System (ADS)

    Hwang, Y. S.; Ono, M.

    1994-10-01

    DC-helicity injection has been successfully applied to the tokamak start-up on CDX-U and CCT tokamaks. Furthermore, CDX-U achieved plasma current levels of up to 10 kA from zero without any ohmic drive. Helicity balance and scaling from CDX-U experiments indicate that plasma current scales with the electron temperature as Te3/2 and it is relatively insensitive to the plasma density. RF heating methods such as electron cyclotron and fast wave heating can be utilized to increase driven plasma current by reducing plasma resistivity. Zero-dimensional modeling has been attempted to design non-inductive start-up and current drive scenarios by combining helicity injection and various RF heating schemes. Plasma current can be driven from zero current by helicity injection and equilibrium field control, and then maintained by helicity injection and bootstrap current with the help of appropriate RF heating to reduce plasma resistivity. Non-inductive start-up and current drive for a 1 MA plasma current in a low-aspect-ratio geometry have been predicted with this model. In a reactor regime, 20 MA of plasma current can be driven and maintained non-inductively with a relatively high efficiency as well.

  4. On a difficulty in eigenfunction expansion solutions for the start-up of fluid flow

    NASA Astrophysics Data System (ADS)

    Christov, Ivan C.

    2015-11-01

    Most mathematics and engineering textbooks describe the process of ``subtracting off'' the steady state of a linear parabolic partial differential equation as a technique for obtaining a boundary-value problem with homogeneous boundary conditions that can be solved by separation of variables (i.e., eigenfunction expansions). While this method produces the correct solution for the start-up of the flow of, e.g., a Newtonian fluid between parallel plates, it can lead to erroneous solutions to the corresponding problem for a class of non-Newtonian fluids. We show that the reason for this is the non-rigorous enforcement of the start-up condition in the textbook approach, which leads to a violation of the principle of causality. Nevertheless, these boundary-value problems can be solved correctly using eigenfunction expansions, and we present the formulation that makes this possible (in essence, an application of Duhamel's principle). The solutions obtained by this new approach are shown to agree identically with those obtained by using the Laplace transform in time only, a technique that enforces the proper start-up condition implicitly (hence, the same error cannot be committed). Supported, in part, by NSF Grant DMS-1104047 and the U.S. DOE (Contract No. DE-AC52-06NA25396) through the LANL/LDRD Program.

  5. Stable plasma start-up in the KSTAR device under various discharge conditions

    NASA Astrophysics Data System (ADS)

    Kim, Jayhyun; Yoon, S. W.; Jeon, Y. M.; Leuer, J. A.; Eidietis, N. W.; Mueller, D.; Park, S.; Nam, Y. U.; Chung, J.; Lee, K. D.; Hahn, S. H.; Bae, Y. S.; Kim, W. C.; Oh, Y. K.; Yang, H. L.; Park, K. R.; Na, H. K.; KSTAR Team

    2011-08-01

    A time series of static nonlinear ferromagnetic calculations was performed to mimic the time-dependent modelling of plasma start-up by assessing the effects of the ferromagnetic Incoloy 908 used in the superconducting coil jackets of the Korea Superconducting Tokamak Advanced Research (KSTAR) device. Time-series calculations of a two-dimensional axisymmetric circuit model with nonlinear ferromagnetic effects enabled us to find appropriate waveforms for the KSTAR poloidal field coil currents that satisfied various start-up requirements, such as the formation and sustainment of field nulls, a sufficient amount of magnetic flux for further plasma current ramp-up, sufficiently large Et ·Bt/Bbottom > 1 kV m-1 contours for successful breakdown, plasma current toroidal equilibria, etc. In addition to the aforementioned requirements, the results introduced in this report also provided the positional stability of the plasma current channel against radial as well as vertical perturbations by compensating the field deformation originating from the ferromagnetic effects. With the improved positional stability, robust plasma start-up was achieved during the 2010 KSTAR campaign under various discharge conditions such as the recovery process from plasma disruptions.

  6. Start-Up Scenario in Gyrotrons with a Nonstationary Microwave-Field Structure

    NASA Astrophysics Data System (ADS)

    Nusinovich, G. S.; Yeddulla, M.; Antonsen, T. M., Jr.; Vlasov, A. N.

    2006-03-01

    Megawatt class gyrotrons operate in very high-order modes. Therefore, control of a gyrotron oscillator’s start-up is important for excitation of the desired mode in the presence of the many undesired modes. Analysis of such scenario using the self-consistent code MAGY [M. Botton , IEEE Trans. Plasma Sci. 26,ITPSBD0093-3813 882 (1998)10.1109/27.700860] reveals that during start-up not only mode amplitudes vary in time, but also their axial structure can be time dependent. Simulations done for a 1.5 MW gyrotron show that the excitation of a single operating TE22,6 mode can exhibit a sort of intermittency when, first, it is excited as a mode whose axial structure extends outside the interaction cavity, then it ceases and then reappears as a mode mostly localized in the cavity. This phenomenon makes it necessary to analyze start-up scenarios in such gyrotrons with the use of codes that account for the possible evolution of field profiles.

  7. Startup of air-cooled condensers and dry cooling towers at low temperatures of the cooling air

    NASA Astrophysics Data System (ADS)

    Milman, O. O.; Ptakhin, A. V.; Kondratev, A. V.; Shifrin, B. A.; Yankov, G. G.

    2016-05-01

    The problems of startup and performance of air-cooled condensers (ACC) and dry cooling towers (DCT) at low cooling air temperatures are considered. Effects of the startup of the ACC at sub-zero temperatures are described. Different options of the ACC heating up are analyzed, and examples of existing technologies are presented (electric heating, heating up with hot air or steam, and internal and external heating). The use of additional heat exchanging sections, steam tracers, in the DCT design is described. The need for high power in cases of electric heating and heating up with hot air is noted. An experimental stand for research and testing of the ACC startup at low temperatures is described. The design of the three-pass ACC unit is given, and its advantages over classical single-pass design at low temperatures are listed. The formation of ice plugs inside the heat exchanging tubes during the start-up of ACC and DCT at low cooling air temperatures is analyzed. Experimental data on the effect of the steam flow rate, steam nozzle distance from the heat-exchange surface, and their orientation in space on the metal temperature were collected, and test results are analyzed. It is noted that the surface temperature at the end of the heat up is almost independent from its initial temperature. Recommendations for the safe start-up of ACCs and DCTs are given. The heating flow necessary to sufficiently heat up heat-exchange surfaces of ACCs and DCTs for the safe startup is estimated. The technology and the process of the heat up of the ACC with the heating steam external supply are described by the example of the startup of the full-scale section of the ACC at sub-zero temperatures of the cooling air, and the advantages of the proposed start-up technology are confirmed.

  8. Substrate-Competitive Activity-Based Profiling of Ester Prodrug Activating Enzymes.

    PubMed

    Xu, Hao; Majmudar, Jaimeen D; Davda, Dahvid; Ghanakota, Phani; Kim, Ki H; Carlson, Heather A; Showalter, Hollis D; Martin, Brent R; Amidon, Gordon L

    2015-09-01

    Understanding the mechanistic basis of prodrug delivery and activation is critical for establishing species-specific prodrug sensitivities necessary for evaluating preclinical animal models and potential drug-drug interactions. Despite significant adoption of prodrug methodologies for enhanced pharmacokinetics, functional annotation of prodrug activating enzymes is laborious and often unaddressed. Activity-based protein profiling (ABPP) describes an emerging chemoproteomic approach to assay active site occupancy within a mechanistically similar enzyme class in native proteomes. The serine hydrolase enzyme family is broadly reactive with reporter-linked fluorophosphonates, which have shown to provide a mechanism-based covalent labeling strategy to assay the activation state and active site occupancy of cellular serine amidases, esterases, and thioesterases. Here we describe a modified ABPP approach using direct substrate competition to identify activating enzymes for an ethyl ester prodrug, the influenza neuraminidase inhibitor oseltamivir. Substrate-competitive ABPP analysis identified carboxylesterase 1 (CES1) as an oseltamivir-activating enzyme in intestinal cell homogenates. Saturating concentrations of oseltamivir lead to a four-fold reduction in the observed rate constant for CES1 inactivation by fluorophosphonates. WWL50, a reported carbamate inhibitor of mouse CES1, blocked oseltamivir hydrolysis activity in human cell homogenates, confirming CES1 is the primary prodrug activating enzyme for oseltamivir in human liver and intestinal cell lines. The related carbamate inhibitor WWL79 inhibited mouse but not human CES1, providing a series of probes for analyzing prodrug activation mechanisms in different preclinical models. Overall, we present a substrate-competitive activity-based profiling approach for broadly surveying candidate prodrug hydrolyzing enzymes and outline the kinetic parameters for activating enzyme discovery, ester prodrug design, and

  9. Substrate-Competitive Activity-Based Profiling of Ester Prodrug Activating Enzymes.

    PubMed

    Xu, Hao; Majmudar, Jaimeen D; Davda, Dahvid; Ghanakota, Phani; Kim, Ki H; Carlson, Heather A; Showalter, Hollis D; Martin, Brent R; Amidon, Gordon L

    2015-09-01

    Understanding the mechanistic basis of prodrug delivery and activation is critical for establishing species-specific prodrug sensitivities necessary for evaluating preclinical animal models and potential drug-drug interactions. Despite significant adoption of prodrug methodologies for enhanced pharmacokinetics, functional annotation of prodrug activating enzymes is laborious and often unaddressed. Activity-based protein profiling (ABPP) describes an emerging chemoproteomic approach to assay active site occupancy within a mechanistically similar enzyme class in native proteomes. The serine hydrolase enzyme family is broadly reactive with reporter-linked fluorophosphonates, which have shown to provide a mechanism-based covalent labeling strategy to assay the activation state and active site occupancy of cellular serine amidases, esterases, and thioesterases. Here we describe a modified ABPP approach using direct substrate competition to identify activating enzymes for an ethyl ester prodrug, the influenza neuraminidase inhibitor oseltamivir. Substrate-competitive ABPP analysis identified carboxylesterase 1 (CES1) as an oseltamivir-activating enzyme in intestinal cell homogenates. Saturating concentrations of oseltamivir lead to a four-fold reduction in the observed rate constant for CES1 inactivation by fluorophosphonates. WWL50, a reported carbamate inhibitor of mouse CES1, blocked oseltamivir hydrolysis activity in human cell homogenates, confirming CES1 is the primary prodrug activating enzyme for oseltamivir in human liver and intestinal cell lines. The related carbamate inhibitor WWL79 inhibited mouse but not human CES1, providing a series of probes for analyzing prodrug activation mechanisms in different preclinical models. Overall, we present a substrate-competitive activity-based profiling approach for broadly surveying candidate prodrug hydrolyzing enzymes and outline the kinetic parameters for activating enzyme discovery, ester prodrug design, and

  10. The activation mechanism of Fe-based olefin metathesis catalysts

    NASA Astrophysics Data System (ADS)

    Poater, Albert; Pump, Eva; Vummaleti, Sai Vikrama Chaitanya; Cavallo, Luigi

    2014-08-01

    Density functional theory calculations have been used to describe the first turnover for olefin metathesis reaction of a homogenous Fe-based catalyst bearing a N-heterocyclic carbene ligand with methoxyethene as a substrate. Equal to conventional Ru-based catalysts, the activation of its Fe congener occurs through a dissociative mechanism, however with a more exothermic reaction energy profile. Predicted upper energy barriers were calculated to be on average ∼2 kcal/mol more beneficial for Fe catalyzed metathesis. Overall, this present computational study emphasises on advantages of Fe-based metathesis and gives a potential recipe for the design of an efficient Fe-based olefin metathesis catalysts.

  11. Estimating evaporative vapor generation from automobiles based on parking activities.

    PubMed

    Dong, Xinyi; Tschantz, Michael; Fu, Joshua S

    2015-07-01

    A new approach is proposed to quantify the evaporative vapor generation based on real parking activity data. As compared to the existing methods, two improvements are applied in this new approach to reduce the uncertainties: First, evaporative vapor generation from diurnal parking events is usually calculated based on estimated average parking duration for the whole fleet, while in this study, vapor generation rate is calculated based on parking activities distribution. Second, rather than using the daily temperature gradient, this study uses hourly temperature observations to derive the hourly incremental vapor generation rates. The parking distribution and hourly incremental vapor generation rates are then adopted with Wade-Reddy's equation to estimate the weighted average evaporative generation. We find that hourly incremental rates can better describe the temporal variations of vapor generation, and the weighted vapor generation rate is 5-8% less than calculation without considering parking activity.

  12. Effects of Gravity on Start-up of a Miniature Loop Heat Pipe with Multiple Evaporators and Multiple Condensers

    NASA Technical Reports Server (NTRS)

    Ku, Jentung; Nagano, Hosei

    2007-01-01

    This paper describes an experimental study on the effect of gravity on the start-up of a miniature loop heat pipe (MLHP) with two evaporators and two condensers. Each evaporator has an outer diameter of 9 mm and has its own integral compensation chamber (CC). The MLHP was placed under five configurations where the relative elevation and tilt among the loop components were varied. The four well-known initial conditions between the evaporator and CC prior to the LHP start-up were created in this experimental study through combinations of: 1) the test configuration; 2) the method of preconditioning the loop prior to start-up, and 3) the heat load distribution among the evaporators. A total of 165 start-ups were conducted under the five test configurations. All of these start-ups were successful. However, the effect of gravity on start-up transients was clearly seen under otherwise the same heat load distribution and sink temperatures. An analytical model was used to simulate the MLHP transient behaviors, and the model predictions agreed very well with the experimental results.

  13. Criticality Benchmark Analysis of the HTTR Annular Startup Core Configurations

    SciTech Connect

    John D. Bess

    2009-11-01

    One of the high priority benchmarking activities for corroborating the Next Generation Nuclear Plant (NGNP) Project and Very High Temperature Reactor (VHTR) Program is evaluation of Japan's existing High Temperature Engineering Test Reactor (HTTR). The HTTR is a 30 MWt engineering test reactor utilizing graphite moderation, helium coolant, and prismatic TRISO fuel. A large amount of critical reactor physics data is available for validation efforts of High Temperature Gas-cooled Reactors (HTGRs). Previous international reactor physics benchmarking activities provided a collation of mixed results that inaccurately predicted actual experimental performance.1 Reevaluations were performed by the Japanese to reduce the discrepancy between actual and computationally-determined critical configurations.2-3 Current efforts at the Idaho National Laboratory (INL) involve development of reactor physics benchmark models in conjunction with the International Reactor Physics Experiment Evaluation Project (IRPhEP) for use with verification and validation methods in the VHTR Program. Annular cores demonstrate inherent safety characteristics that are of interest in developing future HTGRs.

  14. Applying activity-based costing to healthcare settings.

    PubMed

    Canby, J B

    1995-02-01

    Activity-based costing (ABC) focuses on processes that drive cost. By tracing healthcare activities back to events that generate cost, a more accurate measurement of financial performance is possible. This article uses ABC principles and techniques to determine costs associated with the x-ray process in a midsized outpatient clinic. The article also provides several tips for initiating an ABC cost system for an entire healthcare organization. PMID:10146178

  15. Applying activity-based costing to healthcare settings.

    PubMed

    Canby, J B

    1995-02-01

    Activity-based costing (ABC) focuses on processes that drive cost. By tracing healthcare activities back to events that generate cost, a more accurate measurement of financial performance is possible. This article uses ABC principles and techniques to determine costs associated with the x-ray process in a midsized outpatient clinic. The article also provides several tips for initiating an ABC cost system for an entire healthcare organization.

  16. An optimized activity-based probe for the study of caspase-6 activation

    PubMed Central

    Edgington, Laura E.; van Raam, Bram J.; Verdoes, Martijn; Wierschem, Christoph; Salvesen, Guy S.; Bogyo, Matthew

    2012-01-01

    Summary While significant efforts have been made to understand the mechanisms of caspase activation during apoptosis, many questions remain regarding how and when the executioner caspases get activated. We describe the design and synthesis of an activity-based probe that labels caspases-3/-6 /-7, allowing direct monitoring of all executioner caspases simultaneously. This probe has enhanced in vivo properties and reduced cross-reactivity compared to our previously reported probe AB50. Using this probe we find that caspase-6 undergoes a conformational change and can bind substrates even in the absence of cleavage of the pro-enzyme. We also demonstrate that caspase-6 activation does not require active caspases-3/-7 suggesting that it may auto-activate or be cleaved by other proteases. Together, our results suggest that caspase-6 activation proceeds through a unique mechanism that may be important for its diverse biological functions. PMID:22444589

  17. Active-Q: Validation of the Web-Based Physical Activity Questionnaire Using Doubly Labeled Water

    PubMed Central

    Trolle Lagerros, Ylva; Christensen, Sara Elisabeth; Möller, Elisabeth; Wright, Antony; Sjölander, Arvid; Bälter, Katarina

    2012-01-01

    Background Increased use of the Internet provides new opportunities for collecting data in large studies. The aim of our new Web-based questionnaire, Active-Q, is to assess total physical activity and inactivity in adults. Active-Q assesses habitual activity during the past year via questions in four different domains: (1) daily occupation, (2) transportation to and from daily occupation, (3) leisure time activities, and (4) sporting activities. Objective The objective of our study is to validate Active-Q’s energy expenditure estimates using the doubly labeled water (DLW) method, and to assess the reproducibility of Active-Q by comparing the results of the questionnaire completed by the same group on two occasions. Methods The validity and reproducibility of Active-Q were assessed in a group of 37 individuals, aged 20 to 65 years. Active-Q was distributed via email to the participants. The total energy expenditure of the participants was assessed using DLW for 11 consecutive days. Results The median time to complete Active-Q was 6.1 minutes. The majority of participants (27/37, 73%) reported that the questionnaire was “easy” or “very easy” to answer. On average, Active-Q overestimated the total daily energy expenditure by 440 kJ compared with the DLW. The Spearman correlation between the two methods was r = 0.52 (P < .001). The intraclass correlation coefficient for total energy expenditure between the results of Active-Q completed on two occasions was 0.83 (95% CI 0.73-0.93). Conclusions Active-Q is a valid and reproducible method of assessing total energy expenditure. It is also a user-friendly method and suitable for Web-based data collection in large epidemiological studies. PMID:22356755

  18. Activity-based costing for integrated delivery systems.

    PubMed

    Baker, J J

    1995-01-01

    The paradigm shift toward managed care is fueling new cost-finding demands. More sophisticated methods are emerging to meet these demands. Foremost among the new methods is activity-based costing (ABC). ABC is designed to eliminate cross-subsidies between products or services. Because costs are traced by activities across departments and cost centers, costs can also be traced by activities across integrated delivery systems (IDSs). The methodology makes ABC very applicable to combinations of providers including chains, affiliated groups, and IDS participants. PMID:8820298

  19. Activity-based costing for integrated delivery systems.

    PubMed

    Baker, J J

    1995-01-01

    The paradigm shift toward managed care is fueling new cost-finding demands. More sophisticated methods are emerging to meet these demands. Foremost among the new methods is activity-based costing (ABC). ABC is designed to eliminate cross-subsidies between products or services. Because costs are traced by activities across departments and cost centers, costs can also be traced by activities across integrated delivery systems (IDSs). The methodology makes ABC very applicable to combinations of providers including chains, affiliated groups, and IDS participants.

  20. Metal-carbon nanocomposites based on activated IR pyrolized polyacrylonitrile

    NASA Astrophysics Data System (ADS)

    Efimov, Mikhail N.; Zhilyaeva, Natalya A.; Vasilyev, Andrey A.; Muratov, Dmitriy G.; Zemtsov, Lev M.; Karpacheva, Galina P.

    2016-05-01

    In this paper we report about new approach to preparation of metal-carbon nanocomposites based on activated carbon. Polyacrylonitrile is suggested as a precursor for Co, Pd and Ru nanoparticles carbon support which is prepared under IR pyrolysis conditions of a precursor. The first part of the paper is devoted to study activated carbon structural characteristics dependence on activation conditions. In the second part the effect of type of metal introduced in precursor on metal-carbon nanocomposite structural characteristics is shown. Prepared AC and nanocomposite samples are characterized by BET, TEM, SEM and X-ray diffraction.

  1. Engineering Work Plan for the Development of Phased Startup Initiative (PSI) Phases 3 and 4 Test Equipment

    SciTech Connect

    PITNER, A.L.

    2000-04-11

    A number of tools and equipment pieces are required to facilitate planned test operations during Phases 3 and 4 of the Phased Startup Initiative (PSI). These items will be used in assessing residual canister sludge quantities on cleaned fuel assemblies, sorting coarse and fine scrap fuel pieces, assessing the size distribution of scrap pieces, loading scrap into a canister, and measuring the depth of the accumulated scrap in a canister. This work plan supercedes those previously issued for development of several of these test items. These items will be considered prototype equipment until testing has confirmed their suitability for use in K West Basin. The process described in AP-EN-6-032 will be used to qualify the equipment for facility use. These items are considered non-OCRWM for PSI Phase 3 applications. The safety classification of this equipment is General Service, with Quality Level 0 (for PSI Phase 3). Quality Control inspections shall be performed to verify basic dimensions and overall configurations of fabricated components, and any special quality control verifications specified in this work plan (Section 3.1.5). These inspections shall serve to approve the test equipment for use in K West Basin (Acceptance Tag). This equipment is for information gathering only during PSI Phases 3 and 4 activities, and will be discarded at the completion of PSI. For equipment needed to support actual production throughput, development/fabrication/testing activities would be more rigorously controlled.

  2. Tunable dynamics of microtubule-based active isotropic gels

    PubMed Central

    Henkin, Gil; DeCamp, Stephen J.; Chen, Daniel T. N.; Sanchez, Tim; Dogic, Zvonimir

    2014-01-01

    We investigate the dynamics of an active gel of bundled microtubules (MTs) that is driven by clusters of kinesin molecular motors. Upon the addition of ATP, the coordinated action of thousands of molecular motors drives the gel to a highly dynamical turbulent-like state that persists for hours and is only limited by the stability of constituent proteins and the availability of the chemical fuel. We characterize how enhanced transport and emergent macroscopic flows of active gels depend on relevant molecular parameters, including ATP, kinesin motor and depletant concentrations, MT volume fraction, as well as the stoichiometry of the constituent motor clusters. Our results show that the dynamical and structural properties of MT-based active gels are highly tunable. They also indicate existence of an optimal concentration of molecular motors that maximize far-from-equilibrium activity of active isotropic MT gels. PMID:25332391

  3. Synthesis, characterization, theoretical prediction of activities and evaluation of biological activities of some sulfacetamide based hydroxytriazenes.

    PubMed

    Agarwal, Shilpa; Baroliya, Prabhat K; Bhargava, Amit; Tripathi, I P; Goswami, A K

    2016-06-15

    Six new N [(4-aminophenyl)sulfonyl]acetamide based hydroxytriazenes have been synthesized and characterized using elemental analysis, IR, 1H NMR, 13C NMR and MASS spectral analysis. Further, their theoretical predictions for probable activities have been taken using PASS (Prediction of Activity Spectra for Substance). Although a number of activities have been predicted but specifically anti-inflammatory, antiradical, anti-diabetic activities have been experimentally validated which proves that theoretical predictions agree with the experimental results. The object of the Letter is to establish Computer Aided Drug Design (CADD) using our compounds. PMID:27136718

  4. Polynomial optimization techniques for activity scheduling. Optimization based prototype scheduler

    NASA Technical Reports Server (NTRS)

    Reddy, Surender

    1991-01-01

    Polynomial optimization techniques for activity scheduling (optimization based prototype scheduler) are presented in the form of the viewgraphs. The following subject areas are covered: agenda; need and viability of polynomial time techniques for SNC (Space Network Control); an intrinsic characteristic of SN scheduling problem; expected characteristics of the schedule; optimization based scheduling approach; single resource algorithms; decomposition of multiple resource problems; prototype capabilities, characteristics, and test results; computational characteristics; some features of prototyped algorithms; and some related GSFC references.

  5. Understanding human activity patterns based on space-time-semantics

    NASA Astrophysics Data System (ADS)

    Huang, Wei; Li, Songnian

    2016-11-01

    Understanding human activity patterns plays a key role in various applications in an urban environment, such as transportation planning and traffic forecasting, urban planning, public health and safety, and emergency response. Most existing studies in modeling human activity patterns mainly focus on spatiotemporal dimensions, which lacks consideration of underlying semantic context. In fact, what people do and discuss at some places, inferring what is happening at the places, cannot be simple neglected because it is the root of human mobility patterns. We believe that the geo-tagged semantic context, representing what individuals do and discuss at a place and a specific time, drives a formation of specific human activity pattern. In this paper, we aim to model human activity patterns not only based on space and time but also with consideration of associated semantics, and attempt to prove a hypothesis that similar mobility patterns may have different motivations. We develop a spatiotemporal-semantic model to quantitatively express human activity patterns based on topic models, leading to an analysis of space, time and semantics. A case study is conducted using Twitter data in Toronto based on our model. Through computing the similarities between users in terms of spatiotemporal pattern, semantic pattern and spatiotemporal-semantic pattern, we find that only a small number of users (2.72%) have very similar activity patterns, while the majority (87.14%) show different activity patterns (i.e., similar spatiotemporal patterns and different semantic patterns, similar semantic patterns and different spatiotemporal patterns, or different in both). The population of users that has very similar activity patterns is decreased by 56.41% after incorporating semantic information in the corresponding spatiotemporal patterns, which can quantitatively prove the hypothesis.

  6. Changes in microbial community structure correlate with stressed operating conditions during start-up of a field-scale denitrifying fluidized bed reactor

    SciTech Connect

    Hwang, Chaichi; Wu, Wei-min; Gentry, Terry; Carroll, Sue L; Schadt, Christopher Warren; Watson, David B; Jardine, Philip M; Zhou, Jizhong; Hickey, Robert; Criddle, Craig; Fields, Matthew Wayne

    2006-05-01

    High levels of nitrate are present in groundwater migrating from the former waste disposal ponds at the Y-12 National Security Complex in Oak Ridge, TN. A field-scale denitrifying fluidized bed reactor (FBR) was designed, constructed, and operated with ethanol as an electron donor for the removal of nitrate. After inoculation, biofilms developed on the granular activated carbon particles. Changes in the bacterial community of the FBR were evaluated with clone libraries (n=500 partial sequences) of the small-subunit rRNA gene for samples taken over a 4-month start-up period. Early phases of start-up operation were characterized by a period of selection, followed by low diversity and predominance by Azoarcus-like sequences. Possible explanations were high pH and nutrient limitations. After amelioration of these conditions, diversification increased rapidly, with the appearance of Dechloromonas, Pseudomonas, and Hydrogenophaga sequences. Changes in NO{sub 3}, SO{sub 4}, and pH also likely contributed to shifts in community composition. The detection of sulfate-reducing-bacteria-like sequences closely related to Desulfovibrio and Desulfuromonas in the FBR have important implications for downstream applications at the field site.

  7. Active Desiccant-Based Preconditioning Market Analysis and Product Development

    SciTech Connect

    Fischer, J.

    2001-01-11

    The Phase 1 report (ORNL/Sub/94-SVO44/1), completed earlier in this program, involved a comprehensive field survey and market analysis comparing various specialized outdoor air handling units. This initial investigation included conventional cooling and reheat, conventional cooling with sensible recovery, total energy recovery systems (passive desiccant technology) and various active desiccant systems. The report concluded that several markets do promise a significant sales opportunity for a Climate Changer-based active desiccant system offering. (Climate Changer is a registered trademark of Trane Company.) This initial market analysis defined the wants and needs of the end customers (design engineers and building owners), which, along with subsequent information included in this report, have been used to guide the determination of the most promising active desiccant system configurations. This Phase 2 report begins with a summary of a more thorough investigation of those specific markets identified as most promising for active desiccant systems. Table 1 estimates the annual sales potential for a cost-effective product line of active desiccant systems, such as that built from Climate Changer modules. The Product Development Strategy section describes the active desiccant system configurations chosen to best fit the needs of the marketplace while minimizing system options. Key design objectives based on market research are listed in this report for these active desiccant systems. Corresponding performance goals for the dehumidification wheel required to meet the overall system design objectives are also defined. The Performance Modeling section describes the strategy used by SEMCO to design the dehumidification wheels integrated into the prototype systems currently being tested as part of the U.S. Department of Energy's Advanced Desiccant Technology Program. Actual performance data from wheel testing was used to revise the system performance and energy analysis

  8. The discourse of design-based science classroom activities

    NASA Astrophysics Data System (ADS)

    Azevedo, Flávio S.; Martalock, Peggy L.; Keser, Tugba

    2015-06-01

    This paper is an initial contribution to a general theory in which science classroom activity types and epistemological discourse practices are systematically linked. The idea is that activities and discourse are reflexively related, so that different types of science classroom activities (e.g., scientific argumentation, modeling, and design) recruit characteristically distinct forms of participants' (students and teacher) discourse. Such a general theory would eventually map out the full spectrum of discourse practices (and their patterns of manifestation) across various kinds of science classroom activities, and reveal new relationships between forms of both discourse and activities. Because this defines a complex and long-term project, here our aim is simply to delineate this larger theoretical program and to illustrate it with a detailed case study—namely, that of mapping out and characterizing the discourse practices of design- based science classroom activities. To do so, we draw on data from an activity that is prototypically design-based—i.e., one in which students iteratively design and refine an artifact (in this case, pictorial representations of moving objects)—and examine the structure and dynamics of the whole-class discourse practices that emerge around these representational forms. We then compare and contrast these discourse practices to those of an activity that is prototypical of scientific argumentation (taken from the literature)—i.e., one in which students argue between competing theories and explanations of a phenomenon—and begin to illustrate the kinds of insights our theoretical program might afford.

  9. Automatic activity estimation based on object behaviour signature

    NASA Astrophysics Data System (ADS)

    Martínez-Pérez, F. E.; González-Fraga, J. A.; Tentori, M.

    2010-08-01

    Automatic estimation of human activities is a topic widely studied. However the process becomes difficult when we want to estimate activities from a video stream, because human activities are dynamic and complex. Furthermore, we have to take into account the amount of information that images provide, since it makes the modelling and estimation activities a hard work. In this paper we propose a method for activity estimation based on object behavior. Objects are located in a delimited observation area and their handling is recorded with a video camera. Activity estimation can be done automatically by analyzing the video sequences. The proposed method is called "signature recognition" because it considers a space-time signature of the behaviour of objects that are used in particular activities (e.g. patients' care in a healthcare environment for elder people with restricted mobility). A pulse is produced when an object appears in or disappears of the observation area. This means there is a change from zero to one or vice versa. These changes are produced by the identification of the objects with a bank of nonlinear correlation filters. Each object is processed independently and produces its own pulses; hence we are able to recognize several objects with different patterns at the same time. The method is applied to estimate three healthcare-related activities of elder people with restricted mobility.

  10. Review of Scientific & Technical Numeric Data Base Activities.

    ERIC Educational Resources Information Center

    Wood, Barbara L.

    This examination of numeric data base activities grew out of a continuing effort to develop a system of statistical indicators of scientific and technical communication. A broad mix of directories, listing by subject field, reports, mail inquiries and telephone and face-to-face interviews was used to collect information. Scientific and technical…

  11. 24 CFR 576.23 - Faith-based activities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true Faith-based activities. 576.23 Section 576.23 Housing and Urban Development Regulations Relating to Housing and Urban Development... URBAN DEVELOPMENT COMMUNITY FACILITIES EMERGENCY SHELTER GRANTS PROGRAM: STEWART B. McKINNEY...

  12. 24 CFR 585.406 - Faith-based activities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true Faith-based activities. 585.406 Section 585.406 Housing and Urban Development Regulations Relating to Housing and Urban Development... URBAN DEVELOPMENT COMMUNITY FACILITIES YOUTHBUILD PROGRAM Administration § 585.406...

  13. 24 CFR 954.301 - Faith-based activities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... disposition (see 24 CFR parts 84 and 85). (g) If a tribal government voluntarily contributes its own funds to... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Faith-based activities. 954.301 Section 954.301 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN...

  14. Space-Based Astronomy: A Teacher's Guide with Activities.

    ERIC Educational Resources Information Center

    National Aeronautics and Space Administration, Washington, DC.

    This curriculum guide uses hands-on activities to help grade 5-8 students and teachers understand the significance of space-based astronomy--astronomical observations made from outside the Earth's atmosphere. The guide begins with a survey of astronomy-related spacecraft that the National Aeronautics and Space Administration (NASA) has sent into…

  15. 24 CFR 92.257 - Faith-based activities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Development HOME INVESTMENT PARTNERSHIPS PROGRAM Project Requirements § 92.257 Faith-based activities. (a... participate in the HOME program. Neither the Federal government nor a State or local government receiving funds under HOME programs shall discriminate against an organization on the basis of the...

  16. Nanochannel-based electrochemical assay for transglutaminase activity.

    PubMed

    Fernández, Iñigo; Sánchez, Alfredo; Díez, Paula; Martínez-Ruiz, Paloma; Di Pierro, Prospero; Porta, Raffaele; Villalonga, Reynaldo; Pingarrón, José M

    2014-11-11

    A novel electrochemical assay to quantify transglutaminase activity is reported. The assay is based on the enzyme-controlled diffusion of Fe(CN)6(3-/4-) through amino-functionalized nanochannels of a mesoporous silica thin film on a Au surface in the presence of N-benzyloxycarbonyl-L-glutaminylglycine.

  17. A Conceptual Framework Based on Activity Theory for Mobile CSCL

    ERIC Educational Resources Information Center

    Zurita, Gustavo; Nussbaum, Miguel

    2007-01-01

    There is a need for collaborative group activities that promote student social interaction in the classroom. Handheld computers interconnected by a wireless network allow people who work on a common task to interact face to face while maintaining the mediation afforded by a technology-based system. Wirelessly interconnected handhelds open up new…

  18. A Random Forest-based ensemble method for activity recognition.

    PubMed

    Feng, Zengtao; Mo, Lingfei; Li, Meng

    2015-01-01

    This paper presents a multi-sensor ensemble approach to human physical activity (PA) recognition, using random forest. We designed an ensemble learning algorithm, which integrates several independent Random Forest classifiers based on different sensor feature sets to build a more stable, more accurate and faster classifier for human activity recognition. To evaluate the algorithm, PA data collected from the PAMAP (Physical Activity Monitoring for Aging People), which is a standard, publicly available database, was utilized to train and test. The experimental results show that the algorithm is able to correctly recognize 19 PA types with an accuracy of 93.44%, while the training is faster than others. The ensemble classifier system based on the RF (Random Forest) algorithm can achieve high recognition accuracy and fast calculation. PMID:26737432

  19. The Utility of Auroral Image-based Activities Metrics

    NASA Technical Reports Server (NTRS)

    Germany, G.; Spann, J.; Deverapalli, C.; Hung, C.-C.

    2004-01-01

    Auroral activity indices such as Hemispheric Power and Auroral Boundary are currently key data products used for space weather predictions and nowcasting. However, these products are necessarily based on limited observations which must be extrapolated to provide global coverage. The advent of routine space-based auroral imaging in the last decade offers the seeming advantage of more detailed measures of auroral activity. Examples of image-derived products include energy deposition maps, oval location, cap size, and morphological classification. However, activity metrics derived from auroral images have shortcomings, as well. For example, limited fields-of-view and orbital motion prevent full coverage of the auroral regions. This paper will examine the utility of activity metrics derived h m auroral images for operational purposes. The eight-year collection of Polar UVI images databased in the UVI Online Search Tool (OST) will be used to illustrate the advantages and shortcomings of auroral activity metrics. The potential role of other currently-active imaging missions will also be examined and correlative studies to date using auroral imaging will be summarized.

  20. Energy monitoring system based on human activity in the workplace

    NASA Astrophysics Data System (ADS)

    Mustafa, Nur Hanim; Husain, Mohd Nor; Aziz, Mohamad Zoinol Abidin Abdul; Othman, Mohd Azlishah; Malek, Fareq

    2015-05-01

    Human behaviors always related to day routine activities in a smart house directly give the significant factor to manage energy usage in human life. An Addition that, the factor will contribute to the best efficiency of the system. This paper will focus on the monitoring efficiency based on duration time in office hours around 8am until 5pm which depend on human behavior at working place. Besides that, the correlation coefficient method is used to show the relation between energy consumption and energy saving based on the total hours of time energy spent. In future, the percentages of energy monitoring system usage will be increase to manage energy saving based on human behaviors. This scenario will help to see the human activity in the workplace in order to get the energy saving and support world green environment.

  1. [Blood acid-base balance of sportsmen during physical activity].

    PubMed

    Petrushova, O P; Mikulyak, N I

    2014-01-01

    The aim of this study was to investigate the acid-base balance parameters in blood of sportsmen by physical activity. Before exercise lactate concentration in blood was normal. Carbon dioxide pressure (рСО2), bicarbonate concentration (НСО3 -), base excess (BE), were increased immediately after physical activity lactate concentration increased, while pH, BE, НСО3 -, рСО2 decreased in capillary blood of sportsmen. These changes show the development of lactate-acidosis which is partly compensated with bicarbonate buffering system and respiratory alkalosis. During postexercise recovery lactate concentration decreased, while рСО2, НСО3 -, BE increased. The results of this study can be used for diagnostics of acid-base disorders and their medical treatment for preservation of sportsmen physical capacity.

  2. A Variance Based Active Learning Approach for Named Entity Recognition

    NASA Astrophysics Data System (ADS)

    Hassanzadeh, Hamed; Keyvanpour, Mohammadreza

    The cost of manually annotating corpora is one of the significant issues in many text based tasks such as text mining, semantic annotation and generally information extraction. Active Learning is an approach that deals with reduction of labeling costs. In this paper we proposed an effective active learning approach based on minimal variance that reduces manual annotation cost by using a small number of manually labeled examples. In our approach we use a confidence measure based on the model's variance that reaches a considerable accuracy for annotating entities. Conditional Random Field (CRF) is chosen as the underlying learning model due to its promising performance in many sequence labeling tasks. The experiments show that the proposed method needs considerably fewer manual labeled samples to produce a desirable result.

  3. Observation of microtubule-based motor protein activity.

    PubMed

    Sloboda, Roger D

    2015-02-01

    It is possible to detect the presence of motor proteins that have the ability to translocate particles along microtubules. The two procedures described here were developed to detect microtubule-dependent motor protein activity in cell lysates or of purified proteins. In the first procedure, latex beads bound to the putative motor protein are assayed for their ability to translocate along microtubules in an ATP-dependent fashion. If motor protein activity is present, it will bind to the beads and translocate them unidirectionally along the microtubules. In the second procedure, motor proteins induce microtubule gliding over a glass coverslip surface that is coated with active motor protein. Because the mass of a microtubule is negligible compared to that of a coverslip or slide, the microtubule glides over the glass surface when the surface is coated with active motor protein. Also included here are descriptions of assays designed to determine the directionality of movement of microtubule-based motor proteins. PMID:25646501

  4. [Peculicidal activity of plant essential oils and their based preparations].

    PubMed

    Lopatina, Iu V; Eremina, O Iu

    2014-01-01

    The peculicidal activity of eight plant essential oils in 75% isopropyl alcohol was in vitro investigated. Of them, the substances that were most active against lice were tea tree (Melaleuca), eucalyptus, neem, citronella (Cymbopogon nardus), and clove (Syzygium aromaticum) oils; KT50 was not more than 3 minutes on average; KT95 was 4 minutes. After evaporating the solvent, only five (tea tree, cassia, clove, anise (Anisum vulgare), and Japanese star anise (Illicium anisatum) oils) of the eight test botanical substances were active against lice. At the same time, KT50 and KT95 showed 1.5-5-fold increases. Citronella and anise oils had incomplete ovicidal activity. Since the lice were permethrin-resistant, the efficacy of preparations based on essential oils was much higher than permethrin. PMID:25296426

  5. A start-up of psychrophilic anaerobic sequence batch reactor digesting a 35 % total solids feed of dairy manure and wheat straw.

    PubMed

    Saady, Noori M Cata; Massé, Daniel I

    2015-12-01

    Zero liquid discharge is currently an objective in livestock manure management to minimize water pollution. This paper reports the start-up phase of a novel psychrophilic (20 °C) dry anaerobic digestion of dairy manure with bedding fed at 35 % total solids and an organic loading rate of 3.0 g total chemical oxygen demand kg(-1) inoculum day(-1) in anaerobic sequence batch reactors. The specific methane (CH4) yield ranged from 165.4 ± 9.8 to 213.9 ± 13.6 NL CH4 kg(-1) volatile solids (VS) with an overall average of 188 ± 17 NL CH4 kg(-1) VS during 11 successive start-up cycles (231 days) and a maximum CH4 production rate of 10.2 ± 0.6 NL CH4 kg(-1) VS day(-1). The inoculum-to-substrate (VS-based) ratio ranged from 4.06 to 4.47. Although methanogenesis proceeded fairly well the hydrolysis seemed to be the rate limiting step. It is possible start up psychrophilic dry anaerobic digestion of cow feces and wheat straw at feed TS of 35 % within 7-10 successive cycles (147-210 days). PMID:26289773

  6. Determination of allowable fluid temperature during start-up operation of outlet header under the assumption of constant and temperature-dependent material properties

    NASA Astrophysics Data System (ADS)

    Rząsa, Dariusz; Duda, Piotr

    2013-09-01

    Modern supercritical power plants operate at very high temperatures and pressures. Thus the construction elements are subjected to both high thermal and mechanical loads. As a result high stresses in those components are created. In order to operate safely, it is important to monitor stresses, especially during start-up and shut-down processes. The maximum stresses in the construction elements should not exceed the allowable stresses that are defined according to boiler regulations. It is important to find optimum operating parameters, that can assure safe heating and cooling processes. The optimum parameters define temperature and pressure histories that can keep the highest stresses within allowable limit and reduce operation time as much as possible. In this paper a new numerical method for determining optimum working fluid parameters is presented. In this method, properties of steel can be assumed as constant or temperature dependent. The constant value is taken usually at the average temperature of the operation cycle. For both cases optimal parameters are determined. Based on these parameters start-up operations for both cases are conducted. During entire processes stresses in the heated element are monitored. The results obtained are compared with German boiler regulations - Technische Regeln fur Dampfkessel 301.

  7. BENCHMARK EVALUATION OF THE START-UP CORE REACTOR PHYSICS MEASUREMENTS OF THE HIGH TEMPERATURE ENGINEERING TEST REACTOR

    SciTech Connect

    John Darrell Bess

    2010-05-01

    The benchmark evaluation of the start-up core reactor physics measurements performed with Japan’s High Temperature Engineering Test Reactor, in support of the Next Generation Nuclear Plant Project and Very High Temperature Reactor Program activities at the Idaho National Laboratory, has been completed. The evaluation was performed using MCNP5 with ENDF/B-VII.0 nuclear data libraries and according to guidelines provided for inclusion in the International Reactor Physics Experiment Evaluation Project Handbook. Results provided include updated evaluation of the initial six critical core configurations (five annular and one fully-loaded). The calculated keff eigenvalues agree within 1s of the benchmark values. Reactor physics measurements that were evaluated include reactivity effects measurements such as excess reactivity during the core loading process and shutdown margins for the fully-loaded core, four isothermal temperature reactivity coefficient measurements for the fully-loaded core, and axial reaction rate measurements in the instrumentation columns of three core configurations. The calculated values agree well with the benchmark experiment measurements. Fully subcritical and warm critical configurations of the fully-loaded core were also assessed. The calculated keff eigenvalues for these two configurations also agree within 1s of the benchmark values. The reactor physics measurement data can be used in the validation and design development of future High Temperature Gas-cooled Reactor systems.

  8. Start-up of an anaerobic hybrid (UASB/filter) reactor treating wastewater from a coffee processing plant.

    PubMed

    Bello-Mendoza, R; Castillo-Rivera, M F

    1998-10-01

    The ability of an anaerobic hybrid reactor, treating coffee wastewater, to achieve a quick start-up was tested at pilot scale. The unacclimatized seed sludge used showed a low specific methanogenic activity of 26.47 g CH4 as chemical oxygen demand (COD)/kg volatile suspended solids (VSS) x day. This strongly limited the reactor performance. After a few days of operation, a COD removal of 77.2% was obtained at an organic loading rate (OLR) of 1.89 kg COD/m3 x day and a hydraulic retention time (HRT) of 22 h. However, suddenly increasing OLR above 2.4 kg COD/m3 x day resulted in a deterioration in treatment efficiency. The reactor recovered from shock loads after shutdowns of 1 week. The hybrid design of the anaerobic reactor prevented the biomass from washing-out but gas clogging in the packing material was also observed. Wide variations in wastewater strength and flow rates prevented stable reactor operation in the short period of the study.

  9. Start-up of membrane bioreactor and hybrid moving bed biofilm reactor-membrane bioreactor: kinetic study.

    PubMed

    Leyva-Díaz, J C; Poyatos, J M

    2015-01-01

    A hybrid moving bed biofilm reactor-membrane bioreactor (hybrid MBBR-MBR) system was studied as an alternative solution to conventional activated sludge processes and membrane bioreactors. This paper shows the results obtained from three laboratory-scale wastewater treatment plants working in parallel in the start-up and steady states. The first wastewater treatment plant was a MBR, the second one was a hybrid MBBR-MBR system containing carriers both in anoxic and aerobic zones of the bioreactor (hybrid MBBR-MBRa), and the last one was a hybrid MBBR-MBR system which contained carriers only in the aerobic zone (hybrid MBBR-MBRb). The reactors operated with a hydraulic retention time of 30.40 h. A kinetic study for characterizing heterotrophic biomass was carried out and organic matter and nutrients removals were evaluated. The heterotrophic biomass of the hybrid MBBR-MBRb showed the best kinetic performance in the steady state, with yield coefficient for heterotrophic biomass=0.30246 mg volatile suspended solids per mg chemical oxygen demand, maximum specific growth rate for heterotrophic biomass=0.00308 h(-1) and half-saturation coefficient for organic matter=3.54908 mg O2 L(-1). The removal of organic matter was supported by the kinetic study of heterotrophic biomass.

  10. Mechanical shear contributes to granule formation resulting in quick start-up and stability of a hybrid anammox reactor.

    PubMed

    Gao, Yanning; Liu, Zhijun; Liu, Fengxia; Furukawa, Kenji

    2012-06-01

    It appears that if suspended biomass washout can be reduced effectively, granule formation will be fastened in fluidized bed. Quicker reactor start-up can be anticipated especially for those system keeping slow growth bacteria such as anammox. A hybrid reactor combined fixed-bed with nonwoven fabrics as biomass carrier and fluidized bed with slow speed mechanical stirring was therefore developed, and its nitrogen removal performances was evaluated experimentally. Only in 38 days, the total nitrogen removal rate (NRR) reached to 1.9 kg(N) m(-3) day (-1) and then doubled within 17 days, with total nitrogen removal efficiency kept above 70%. After 180 days reactor operating, the NRR reached a maximum value of 6.6 kg(N) m(-3) day(-1) and the specific anammox activity was gradually constant in 0.32 kg(N) kg(VSS)(-1) day(-1). Biomass attached on nonwoven fabrics could additionally improve reactor nitrogen removal by 8%. The dominant size of granular sludge reached to 0.78 mm with stirring speed adjusted from 30 to 80 rpm and the hydraulic retention time (HRT) from 8 to 1.5 h during the whole operating time. Scanning electron microscope observation showed especially compact structure of granular sludge. A 70% of anammox bacteria percentage was identified by fluorescence in situ hybridization analysis. PMID:21928094

  11. Unsupervised active learning based on hierarchical graph-theoretic clustering.

    PubMed

    Hu, Weiming; Hu, Wei; Xie, Nianhua; Maybank, Steve

    2009-10-01

    Most existing active learning approaches are supervised. Supervised active learning has the following problems: inefficiency in dealing with the semantic gap between the distribution of samples in the feature space and their labels, lack of ability in selecting new samples that belong to new categories that have not yet appeared in the training samples, and lack of adaptability to changes in the semantic interpretation of sample categories. To tackle these problems, we propose an unsupervised active learning framework based on hierarchical graph-theoretic clustering. In the framework, two promising graph-theoretic clustering algorithms, namely, dominant-set clustering and spectral clustering, are combined in a hierarchical fashion. Our framework has some advantages, such as ease of implementation, flexibility in architecture, and adaptability to changes in the labeling. Evaluations on data sets for network intrusion detection, image classification, and video classification have demonstrated that our active learning framework can effectively reduce the workload of manual classification while maintaining a high accuracy of automatic classification. It is shown that, overall, our framework outperforms the support-vector-machine-based supervised active learning, particularly in terms of dealing much more efficiently with new samples whose categories have not yet appeared in the training samples. PMID:19336318

  12. ActivitySim: large-scale agent based activity generation for infrastructure simulation

    SciTech Connect

    Gali, Emmanuel; Eidenbenz, Stephan; Mniszewski, Sue; Cuellar, Leticia; Teuscher, Christof

    2008-01-01

    The United States' Department of Homeland Security aims to model, simulate, and analyze critical infrastructure and their interdependencies across multiple sectors such as electric power, telecommunications, water distribution, transportation, etc. We introduce ActivitySim, an activity simulator for a population of millions of individual agents each characterized by a set of demographic attributes that is based on US census data. ActivitySim generates daily schedules for each agent that consists of a sequence of activities, such as sleeping, shopping, working etc., each being scheduled at a geographic location, such as businesses or private residences that is appropriate for the activity type and for the personal situation of the agent. ActivitySim has been developed as part of a larger effort to understand the interdependencies among national infrastructure networks and their demand profiles that emerge from the different activities of individuals in baseline scenarios as well as emergency scenarios, such as hurricane evacuations. We present the scalable software engineering principles underlying ActivitySim, the socia-technical modeling paradigms that drive the activity generation, and proof-of-principle results for a scenario in the Twin Cities, MN area of 2.6 M agents.

  13. Activity based chemical proteomics: profiling proteases as drug targets.

    PubMed

    Heal, William Percy; Wickramasinghe, Sasala Roshinie; Tate, Edward William

    2008-09-01

    The pivotal role of proteases in many diseases has generated considerable interest in their basic biology, and in the potential to target them for chemotherapy. Although fundamental to the initiation and progression of diseases such as cancer, diabetes, arthritis and malaria, in many cases their precise role remains unknown. Activity-based chemical proteomics-an emerging field involving a combination of organic synthesis, biochemistry, cell biology, biophysics and bioinformatics-allows the detection, visualisation and activity quantification of whole families or selected sub-sets of proteases based upon their substrate specificity. This approach can be applied for drug target/lead identification and validation, the fundamentals of drug discovery. The activity-based probes discussed in this review contain three key features; a 'warhead' (binds irreversibly but selectively to the active site), a 'tag' (allowing enzyme 'handling', with a combination of fluorescent, affinity and/or radio labels), and a linker region between warhead and tag. From the design and synthesis of the linker arise some of the latest developments discussed here; not only can the physical properties (e.g., solubility, localisation) of the probe be tuned, but the inclusion of a cleavable moiety allows selective removal of tagged enzyme from affinity beads etc. The design and synthesis of recently reported probes is discussed, including modular assembly of highly versatile probes via solid phase synthesis. Recent applications of activity-based protein profiling to specific proteases (serine, threonine, cysteine and metalloproteases) are reviewed as are demonstrations of their use in the study of disease function in cancer and malaria.

  14. 45 CFR 309.150 - What start-up costs are allowable for Tribal IV-D programs carried out under § 309.65(b) of this...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false What start-up costs are allowable for Tribal IV-D... ENFORCEMENT (IV-D) PROGRAM Tribal IV-D Program Funding § 309.150 What start-up costs are allowable for Tribal... $500,000, unless additional funding is provided pursuant to § 309.16(c). Allowable start-up costs...

  15. 45 CFR 309.150 - What start-up costs are allowable for Tribal IV-D programs carried out under § 309.65(b) of this...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false What start-up costs are allowable for Tribal IV-D... ENFORCEMENT (IV-D) PROGRAM Tribal IV-D Program Funding § 309.150 What start-up costs are allowable for Tribal... $500,000, unless additional funding is provided pursuant to § 309.16(c). Allowable start-up costs...

  16. Manned spaceflight activity planning with knowledge-based systems

    NASA Technical Reports Server (NTRS)

    Mogilensky, J.; Dalton, R. E.; Scarl, E. A.

    1983-01-01

    An on-board expert system, capable of assisting with crew-activity planning and platform-status monitoring, could provide unprecedented autonomy to the crew of a permanently manned space station. To demonstrate this concept's feasibility, an existing knowledge-based system is adapted to support Space Shuttle crew-activity timeline planning. Proposed timeline changes are to be checked for compliance with crew capabilities and mission operating guidelines, so that a nonexpert can be guided through a successful plan modification. Early lessons that have been learned about the scope of the adaptation needed to achieve this objective are presented.

  17. Modeling earthquake activity using a memristor-based cellular grid

    NASA Astrophysics Data System (ADS)

    Vourkas, Ioannis; Sirakoulis, Georgios Ch.

    2013-04-01

    Earthquakes are absolutely among the most devastating natural phenomena because of their immediate and long-term severe consequences. Earthquake activity modeling, especially in areas known to experience frequent large earthquakes, could lead to improvements in infrastructure development that will prevent possible loss of lives and property damage. An earthquake process is inherently a nonlinear complex system and lately scientists have become interested in finding possible analogues of earthquake dynamics. The majority of the models developed so far were based on a mass-spring model of either one or two dimensions. An early approach towards the reordering and the improvement of existing models presenting the capacitor-inductor (LC) analogue, where the LC circuit resembles a mass-spring system and simulates earthquake activity, was also published recently. Electromagnetic oscillation occurs when energy is transferred between the capacitor and the inductor. This energy transformation is similar to the mechanical oscillation that takes place in the mass-spring system. A few years ago memristor-based oscillators were used as learning circuits exposed to a train of voltage pulses that mimic environment changes. The mathematical foundation of the memristor (memory resistor), as the fourth fundamental passive element, has been expounded by Leon Chua and later extended to a more broad class of memristors, known as memristive devices and systems. This class of two-terminal passive circuit elements with memory performs both information processing and storing of computational data on the same physical platform. Importantly, the states of these devices adjust to input signals and provide analog capabilities unavailable in standard circuit elements, resulting in adaptive circuitry and providing analog parallel computation. In this work, a memristor-based cellular grid is used to model earthquake activity. An LC contour along with a memristor is used to model seismic activity

  18. Frequency Based Volcanic Activity Detection through Remotely Sensed Data

    NASA Astrophysics Data System (ADS)

    Worden, A. K.; Dehn, J.; Webley, P. W.

    2015-12-01

    Satellite remote sensing has proved to offer a useful and relatively inexpensive method for monitoring large areas where field work is logistically unrealistic, and potentially dangerous. Current sensors are able to detect the majority of explosive volcanic activity; those that tend to effect and represent larger scale changes in the volcanic systems, eventually relating to ash producing periods of extended eruptive activity, and effusive activity. As new spaceborne sensors are developed, the ability to detect activity improves so that a system to gauge the frequency of volcanic activity can be used as a useful monitoring tool. Four volcanoes were chosen for development and testing of a method to monitor explosive activity: Stromboli (Italy); Shishaldin and Cleveland (Alaska, USA); and Karymsky (Kamchatka, Russia). Each volcano studied had similar but unique signatures of pre-cursory and eruptive activity. This study has shown that this monitoring tool could be applied to a wide range of volcanoes and still produce useful and robust data. Our method deals specifically with the detection of small scale explosive activity. The method described here could be useful in an operational setting, especially at remote volcanoes that have the potential to impact populations, infrastructure, and the aviation community. A number of important factors will affect the validity of application of this method. They are: (1) the availability of a continuous and continually populated dataset; (2) appropriate and reasonable sensor resolutions; (3) a recorded history of the volcano's previous activity; and, if available, (4) some ground-based monitoring system. We aim to develop the method further to be able to capture and evaluate the frequency of other volcanic processes such as lava flows, phreatomagmatic eruptions and dome growth and collapse. The work shown here has served to illustrate the capability of this method and monitoring tool for use at remote, un-instrumented volcanoes.

  19. Plasma start-up results with electron cyclotron assisted breakdown on Frascati Tokamak Upgrade

    NASA Astrophysics Data System (ADS)

    Granucci, G.; Ramponi, G.; Calabrò, G.; Crisanti, F.; Nowak, S.; Ramogida, G.; Tudisco, O.; Bin, W.; Botrugno, A.; Buratti, P.; D'Arcangelo, O.; Frigione, D.; Pucella, G.; Romano, A.; FTU Team

    2011-07-01

    Several experiments aimed at optimizing plasma pre-ionization using electron cyclotron (EC) waves have been carried out on many tokamaks in recent years as the basis of a multi-machine comparison study made to define the best operation scenarios for ITER, where the plasma breakdown will have to be achieved with a toroidal electric field of only 0.3 V m-1. The FTU (Frascati Tokamak Upgrade, R = 0.935 m, a = 0.3 m) contribution to this study is the main subject of this work. A reduction in electric field, as can be obtained with pre-ionization by ECH, can lower the transformer flux consumption in the start-up phase leading to a longer plasma current flat top. This point is of particular interest in the conceptual design of the steady-state scenario of the proposed FAST tokamak and has also been addressed. In the FTU experiment the scan in pre-filling pressure has evidenced the capability of EC power to increase, by a factor 4, the range of working pressure useful for plasma start-up. Varying the breakdown a minimum electric field of 0.41 V m-1 has been found with 0.8 MW of EC in perpendicular injection. A scan in magnetic field has evidenced that plasma start-up is likely insensitive to alignment between EC resonance and null position. A total transformer flux saving of 22% has been found acting on plasma resistivity (by increasing electron temperature) and on the plasma starting point (for an internal inductance reduction).

  20. Design and startup of a high efficiency, dilute phase lime FGD system

    SciTech Connect

    Walsh, M.; Cirillo, A.J.

    1995-06-01

    The Clean Air Act Amendments mandated large reductions in SO{sub 2} emissions from utility coal-fired boilers. For the operating companies of the Allegheny Power System (APS), this presented numerous challenges due to the system`s dependence on coal fuel. Although the Clean Air Act Amendments mandated approximately 50% reduction in SO{sub 2} at eleven (11) generating units within the Allegheny system, economic studies revealed that high efficiency scrubbers, placed on the largest units, would provide the most cost effective method to reduce SO{sub 2} emissions. Accordingly, the three units at Harrison Power Station, with a total generating capacity of 1,920 MW, were targeted for wet, magnesium enhanced, lime scrubbing. The scrubbing of the Harrison Power Station represented the cornerstone of Allegheny`s Phase I Clean Air Act compliance strategy for SO{sub 2} only. At the heart of the Flue Gas Desulfurization System (FGD) are high efficiency absorber towers utilizing magnesium-enhanced lime as the reagent. Use of a single, large absorber tower on each of Harrison`s three 640 MW units will result in guaranteed SO{sub 2} removal efficiencies of 98% with only three recycle pumps operating. In addition to discussing the overall FGD system`s design, this paper will address the following items: (1) Reliability of Large Single Tower Scrubbing (European experience and use of an absorber tower scale model for gas and liquid flow distribution); (2) Absorber Process Chemistry and Dilute Phase FGD System Startup and Operation. In conjunction with the aforementioned process design features of the Harrison Power Station FGD System, the startup and operational aspects of the scrubber system will be reviewed. Specifically, the simplified startup and operation of these wet scrubbers, owing to the minimization of the quantity of components required to be installed, tested and maintained compared to multiple absorber modules per boiler unit, will be addressed.

  1. Making activity-based funding work for mental health.

    PubMed

    Rosenberg, Sebastian P; Hickie, Ian B

    2013-06-01

    The implementation of activity-based funding (ABF) in mental health from 1 July 2013 has significant risks and benefits. It is critical that the process of implementation is consistent with Australia's cherished goal of establishing a genuine and effective model of community-based mental health care. The infrastructure to support the application of ABF to mental health is currently weak and requires considerable development. States and territories are struggling to meet existing demand for largely hospital-based acute mental health care. There is a risk that valuable ABF-driven Commonwealth growth funds may be used to prop up these systems rather than drive the emergence of new models of community-based care. Some of these new models exist now and this article provides a short description. The aim is to help the Independent Hospital Pricing Authority better understand the landscape of mental health into which it now seeks to deploy ABF.

  2. Medical Image Segmentation Based on a Hybrid Region-Based Active Contour Model

    PubMed Central

    Liu, Tingting; Xu, Haiyong; Liu, Zhen; Zhao, Yiming; Tian, Wenzhe

    2014-01-01

    A novel hybrid region-based active contour model is presented to segment medical images with intensity inhomogeneity. The energy functional for the proposed model consists of three weighted terms: global term, local term, and regularization term. The total energy is incorporated into a level set formulation with a level set regularization term, from which a curve evolution equation is derived for energy minimization. Experiments on some synthetic and real images demonstrate that our model is more efficient compared with the localizing region-based active contours (LRBAC) method, proposed by Lankton, and more robust compared with the Chan-Vese (C-V) active contour model. PMID:25028593

  3. Modeling of two-phase flow instabilities during startup transients utilizing RAMONA-4B methodology

    SciTech Connect

    Paniagua, J.; Rohatgi, U.S.; Prasad, V.

    1996-10-01

    RAMONA-4B code is currently under development for simulating thermal hydraulic instabilities that can occur in Boiling Water Reactors (BWRs) and the Simplified Boiling Water Reactor (SBWR). As one of the missions of RAMONA-4B is to simulate SBWR startup transients, where geysering or condensation-induced instability may be encountered, the code needs to be assessed for this application. This paper outlines the results of the assessments of the current version of RAMONA-4B and the modifications necessary for simulating the geysering or condensation-induced instability. The test selected for assessment are the geysering tests performed by Prof Aritomi (1993).

  4. Vapor Flow Patterns During a Start-Up Transient in Heat Pipes

    NASA Technical Reports Server (NTRS)

    Issacci, F.; Ghoniem, N, M.; Catton, I.

    1996-01-01

    The vapor flow patterns in heat pipes are examined during the start-up transient phase. The vapor core is modelled as a channel flow using a two dimensional compressible flow model. A nonlinear filtering technique is used as a post process to eliminate the non-physical oscillations of the flow variables. For high-input heat flux, multiple shock reflections are observed in the evaporation region. The reflections cause a reverse flow in the evaporation and circulations in the adiabatic region. Furthermore, each shock reflection causes a significant increase in the local pressure and a large pressure drop along the heat pipe.

  5. LETTER: Electron Bernstein wave assisted plasma current start-up in MAST

    NASA Astrophysics Data System (ADS)

    Shevchenko, V. F.; O'Brien, M. R.; Taylor, D.; Saveliev, A. N.; MAST Team

    2010-02-01

    Electron Bernstein wave (EBW) assisted plasma current start-up has been demonstrated for the first time in a tokamak. It was shown that plasma currents up to 17 kA can be generated non-inductively by 100 kW of RF power injected. With optimized vertical field ramps, plasma currents up to 33 kA have been achieved without the use of solenoid flux. It is shown that the plasma formation and current generation are governed predominantly by EBW current drive. Experimental results are consistent with ray-tracing and quasilinear Fokker-Planck modelling.

  6. An Electronic Library-Based Learning Environment for Supporting Web-Based Problem-Solving Activities

    ERIC Educational Resources Information Center

    Tsai, Pei-Shan; Hwang, Gwo-Jen; Tsai, Chin-Chung; Hung, Chun-Ming; Huang, Iwen

    2012-01-01

    This study aims to develop an electronic library-based learning environment to support teachers in developing web-based problem-solving activities and analyzing the online problem-solving behaviors of students. Two experiments were performed in this study. In study 1, an experiment on 103 elementary and high school teachers (the learning activity…

  7. Prediction of Solar Activity Based on Neuro-Fuzzy Modeling

    NASA Astrophysics Data System (ADS)

    Attia, Abdel-Fattah; Abdel-Hamid, Rabab; Quassim, Maha

    2005-03-01

    This paper presents an application of the neuro-fuzzy modeling to analyze the time series of solar activity, as measured through the relative Wolf number. The neuro-fuzzy structure is optimized based on the linear adapted genetic algorithm with controlling population size (LAGA-POP). Initially, the dimension of the time series characteristic attractor is obtained based on the smallest regularity criterion (RC) and the neuro-fuzzy model. Then the performance of the proposed approach, in forecasting yearly sunspot numbers, is favorably compared to that of other published methods. Finally, a comparison predictions for the remaining part of the 22nd and the whole 23rd cycle of the solar activity are presented.

  8. Time-Driven Activity-Based Costing in Emergency Medicine.

    PubMed

    Yun, Brian J; Prabhakar, Anand M; Warsh, Jonathan; Kaplan, Robert; Brennan, John; Dempsey, Kyle E; Raja, Ali S

    2016-06-01

    Value in emergency medicine is determined by both patient-important outcomes and the costs associated with achieving them. However, measuring true costs is challenging. Without an understanding of costs, emergency department (ED) leaders will be unable to determine which interventions might improve value for their patients. Although ongoing research may determine which outcomes are meaningful, an accurate costing system is also needed. This article reviews current costing mechanisms in the ED and their pitfalls. It then describes how time-driven activity-based costing may be superior to these current costing systems. Time-driven activity-based costing, in addition to being a more accurate costing system, can be used for process improvements in the ED. PMID:26365921

  9. Time-Driven Activity-Based Costing in Emergency Medicine.

    PubMed

    Yun, Brian J; Prabhakar, Anand M; Warsh, Jonathan; Kaplan, Robert; Brennan, John; Dempsey, Kyle E; Raja, Ali S

    2016-06-01

    Value in emergency medicine is determined by both patient-important outcomes and the costs associated with achieving them. However, measuring true costs is challenging. Without an understanding of costs, emergency department (ED) leaders will be unable to determine which interventions might improve value for their patients. Although ongoing research may determine which outcomes are meaningful, an accurate costing system is also needed. This article reviews current costing mechanisms in the ED and their pitfalls. It then describes how time-driven activity-based costing may be superior to these current costing systems. Time-driven activity-based costing, in addition to being a more accurate costing system, can be used for process improvements in the ED.

  10. Focus of attention in an activity-based scheduler

    NASA Technical Reports Server (NTRS)

    Sadeh, Norman; Fox, Mark S.

    1989-01-01

    Earlier research in job shop scheduling has demonstrated the advantages of opportunistically combining order-based and resource-based scheduling techniques. An even more flexible approach is investigated where each activity is considered a decision point by itself. Heuristics to opportunistically select the next decision point on which to focus attention (i.e., variable ordering heuristics) and the next decision to be tried at this point (i.e., value ordering heuristics) are described that probabilistically account for both activity precedence and resource requirement interactions. Preliminary experimental results indicate that the variable ordering heuristic greatly increases search efficiency. While least constraining value ordering heuristics have been advocated in the literature, the experimental results suggest that other value ordering heuristics combined with our variable-ordering heuristic can produce much better schedules without significantly increasing search.

  11. Surface-to-surface biofilm transfer: a quick and reliable startup strategy for mixed culture microbial fuel cells.

    PubMed

    Vogl, Andreas; Bischof, Franz; Wichern, Marc

    2016-01-01

    The startup of microbial fuel cells (MFCs) is known to be prone to failure or result in erratic performance impeding the research. The aim of this study was to advise a quick launch strategy for laboratory-scale MFCs that ensures steady operation performance in a short period of time. Different startup strategies were investigated and compared with membraneless single chamber MFCs. A direct surface-to-surface biofilm transfer (BFT) in an operating MFC proved to be the most efficient method. It provided steady power densities of 163 ± 13 mWm(-2) 4 days after inoculation compared to 58 ± 15 mWm(-2) after 30 days following a conventional inoculation approach. The in situ BFT eliminates the need for microbial acclimation during startup and reduces performance fluctuations caused by shifts in microbial biodiversity. Anaerobic pretreatment of the substrate and addition of suspended enzymes from an operating MFC into the new MFC proved to have a beneficial effect on startup and subsequent operation. Polarization methods were applied to characterize the startup phase and the steady state operation in terms of power densities, internal resistance and power overshoot during biofilm maturation. Applying this method a well-working MFC can be multiplied into an array of identically performing MFCs. PMID:27120629

  12. Advanced extravehicular activity systems requirements definition study. Phase 2: Extravehicular activity at a lunar base

    NASA Technical Reports Server (NTRS)

    Neal, Valerie; Shields, Nicholas, Jr.; Carr, Gerald P.; Pogue, William; Schmitt, Harrison H.; Schulze, Arthur E.

    1988-01-01

    The focus is on Extravehicular Activity (EVA) systems requirements definition for an advanced space mission: remote-from-main base EVA on the Moon. The lunar environment, biomedical considerations, appropriate hardware design criteria, hardware and interface requirements, and key technical issues for advanced lunar EVA were examined. Six remote EVA scenarios (three nominal operations and three contingency situations) were developed in considerable detail.

  13. Batch Mode Active Sampling based on Marginal Probability Distribution Matching.

    PubMed

    Chattopadhyay, Rita; Wang, Zheng; Fan, Wei; Davidson, Ian; Panchanathan, Sethuraman; Ye, Jieping

    2012-01-01

    Active Learning is a machine learning and data mining technique that selects the most informative samples for labeling and uses them as training data; it is especially useful when there are large amount of unlabeled data and labeling them is expensive. Recently, batch-mode active learning, where a set of samples are selected concurrently for labeling, based on their collective merit, has attracted a lot of attention. The objective of batch-mode active learning is to select a set of informative samples so that a classifier learned on these samples has good generalization performance on the unlabeled data. Most of the existing batch-mode active learning methodologies try to achieve this by selecting samples based on varied criteria. In this paper we propose a novel criterion which achieves good generalization performance of a classifier by specifically selecting a set of query samples that minimizes the difference in distribution between the labeled and the unlabeled data, after annotation. We explicitly measure this difference based on all candidate subsets of the unlabeled data and select the best subset. The proposed objective is an NP-hard integer programming optimization problem. We provide two optimization techniques to solve this problem. In the first one, the problem is transformed into a convex quadratic programming problem and in the second method the problem is transformed into a linear programming problem. Our empirical studies using publicly available UCI datasets and a biomedical image dataset demonstrate the effectiveness of the proposed approach in comparison with the state-of-the-art batch-mode active learning methods. We also present two extensions of the proposed approach, which incorporate uncertainty of the predicted labels of the unlabeled data and transfer learning in the proposed formulation. Our empirical studies on UCI datasets show that incorporation of uncertainty information improves performance at later iterations while our studies on 20

  14. Charge dependent photodynamic activity of alanine based zinc phthalocyanines.

    PubMed

    Wang, Ao; Li, Yejing; Zhou, Lin; Yuan, Linxin; Lu, Shan; Lin, Yun; Zhou, Jiahong; Wei, Shaohua

    2014-12-01

    In this paper, to minimize the effects of different structure, three alanine-based zinc phthalocyanines (Pcs) of differing charges were engineered and synthesized with the same basic structure. On this premise, the relationship between nature of charge and photodynamic activity was studied. Besides, further verification and explanation of some inconsistent results were also carried out. The results showed that charge can influence the aggregation state, singlet oxygen generation ability and cellular uptake of Pcs, thereby affecting their photodynamic activity. In addition, the biomolecules inside cells may interact with Pcs of differing charges, which can also influence the aggregation state and singlet oxygen generation of the Pcs, and then influence the relationship between nature of charge and photodynamic activity.

  15. Mathematical framework for activity-based cancer biomarkers.

    PubMed

    Kwong, Gabriel A; Dudani, Jaideep S; Carrodeguas, Emmanuel; Mazumdar, Eric V; Zekavat, Seyedeh M; Bhatia, Sangeeta N

    2015-10-13

    Advances in nanomedicine are providing sophisticated functions to precisely control the behavior of nanoscale drugs and diagnostics. Strategies that coopt protease activity as molecular triggers are increasingly important in nanoparticle design, yet the pharmacokinetics of these systems are challenging to understand without a quantitative framework to reveal nonintuitive associations. We describe a multicompartment mathematical model to predict strategies for ultrasensitive detection of cancer using synthetic biomarkers, a class of activity-based probes that amplify cancer-derived signals into urine as a noninvasive diagnostic. Using a model formulation made of a PEG core conjugated with protease-cleavable peptides, we explore a vast design space and identify guidelines for increasing sensitivity that depend on critical parameters such as enzyme kinetics, dosage, and probe stability. According to this model, synthetic biomarkers that circulate in stealth but then activate at sites of disease have the theoretical capacity to discriminate tumors as small as 5 mm in diameter-a threshold sensitivity that is otherwise challenging for medical imaging and blood biomarkers to achieve. This model may be adapted to describe the behavior of additional activity-based approaches to allow cross-platform comparisons, and to predict allometric scaling across species.

  16. Activity-based analyses lead to better decision making.

    PubMed

    Player, S

    1998-08-01

    Activity-based costing (ABC) and activity-based management (ABM) are cost-management tools that are relatively new to the healthcare industry. ABC is used for strategic decision making. It assesses the costs associated with specific activities and resources and links those costs to specific internal and external customers of the healthcare enterprise (e.g., patients, service lines, and physician groups) to determine the costs associated with each customer. This cost information then can be adjusted to account for anticipated changes and to predict future costs. ABM, on the other hand, supports operations by focusing on the causes of costs and how costs can be reduced. It assesses cost drivers that directly affect the cost of a product or service, and uses performance measures to evaluate the financial or nonfinancial benefit an activity provides. By identifying each cost driver and assessing the value the element adds to the healthcare enterprise, ABM provides a basis for selecting areas that can be changed to reduce costs. PMID:10182280

  17. Data correction for seven activity trackers based on regression models.

    PubMed

    Andalibi, Vafa; Honko, Harri; Christophe, Francois; Viik, Jari

    2015-08-01

    Using an activity tracker for measuring activity-related parameters, e.g. steps and energy expenditure (EE), can be very helpful in assisting a person's fitness improvement. Unlike the measuring of number of steps, an accurate EE estimation requires additional personal information as well as accurate velocity of movement, which is hard to achieve due to inaccuracy of sensors. In this paper, we have evaluated regression-based models to improve the precision for both steps and EE estimation. For this purpose, data of seven activity trackers and two reference devices was collected from 20 young adult volunteers wearing all devices at once in three different tests, namely 60-minute office work, 6-hour overall activity and 60-minute walking. Reference data is used to create regression models for each device and relative percentage errors of adjusted values are then statistically compared to that of original values. The effectiveness of regression models are determined based on the result of a statistical test. During a walking period, EE measurement was improved in all devices. The step measurement was also improved in five of them. The results show that improvement of EE estimation is possible only with low-cost implementation of fitting model over the collected data e.g. in the app or in corresponding service back-end. PMID:26736578

  18. Mathematical framework for activity-based cancer biomarkers.

    PubMed

    Kwong, Gabriel A; Dudani, Jaideep S; Carrodeguas, Emmanuel; Mazumdar, Eric V; Zekavat, Seyedeh M; Bhatia, Sangeeta N

    2015-10-13

    Advances in nanomedicine are providing sophisticated functions to precisely control the behavior of nanoscale drugs and diagnostics. Strategies that coopt protease activity as molecular triggers are increasingly important in nanoparticle design, yet the pharmacokinetics of these systems are challenging to understand without a quantitative framework to reveal nonintuitive associations. We describe a multicompartment mathematical model to predict strategies for ultrasensitive detection of cancer using synthetic biomarkers, a class of activity-based probes that amplify cancer-derived signals into urine as a noninvasive diagnostic. Using a model formulation made of a PEG core conjugated with protease-cleavable peptides, we explore a vast design space and identify guidelines for increasing sensitivity that depend on critical parameters such as enzyme kinetics, dosage, and probe stability. According to this model, synthetic biomarkers that circulate in stealth but then activate at sites of disease have the theoretical capacity to discriminate tumors as small as 5 mm in diameter-a threshold sensitivity that is otherwise challenging for medical imaging and blood biomarkers to achieve. This model may be adapted to describe the behavior of additional activity-based approaches to allow cross-platform comparisons, and to predict allometric scaling across species. PMID:26417077

  19. The utilization of activity-based cost accounting in hospitals.

    PubMed

    Emmett, Dennis; Forget, Robert

    2005-01-01

    Healthcare costs are being examined on all fronts. Healthcare accounts for 11% of the gross national product and will continue to rise as the "babyboomers" reach retirement age. While ascertaining costs is important, most research shows that costing methods have not been implemented in hospitals. This study is concerned with the use of costing methods; particularly activity-based cost accounting. A mail survey of CFOs was undertaken to determine the type of cost accounting method they use. In addition, they were asked whether they were aware of activity-based cost accounting and whether they had implemented it or were planning to implement it. Only 71.8% were aware of it and only 4.7% had implemented it. In addition, only 52% of all hospitals report using any cost accounting systems. Education needs to ensure that all healthcare executives are cognizant of activity-based accounting and its importance in determining costs. Only by determining costs can hospitals strive to contain them.

  20. Process-Based Governance in Public Administrations Using Activity-Based Costing

    NASA Astrophysics Data System (ADS)

    Becker, Jörg; Bergener, Philipp; Räckers, Michael

    Decision- and policy-makers in public administrations currently lack on missing relevant information for sufficient governance. In Germany the introduction of New Public Management and double-entry accounting enable public administrations to get the opportunity to use cost-centered accounting mechanisms to establish new governance mechanisms. Process modelling in this case can be a useful instrument to help the public administrations decision- and policy-makers to structure their activities and capture relevant information. In combination with approaches like Activity-Based Costing, higher management level can be supported with a reasonable data base for fruitful and reasonable governance approaches. Therefore, the aim of this article is combining the public sector domain specific process modelling method PICTURE and concept of activity-based costing for supporting Public Administrations in process-based Governance.

  1. Geomagnetic Activity Forecast based on SW-M-I coupling

    NASA Astrophysics Data System (ADS)

    Nagatsuma, T.

    2009-12-01

    The geomagnetic activity shows diurnal and semiannual and solar cycle variations. The cause of these variations consists of two effects. One is the periodical change of the solar wind parameters due to a variation of the geometrical condition between the solar wind and the Earth’s magnetosphere. The other is the periodical change of the SW-M-I coupling efficiency caused by the changing of ionospheric conductivity in the polar cap region. Therefore, operational forecasting model of geomagnetic activity should take into account these variations and dependence. We have developed the empirical model for forecasting geomagnetic activity considering the change of the SW-M-I coupling efficiency. This model can reproduce Equinoctial effect and solar cycle dependence of geomagnetic activity. Further, we have found that the efficiency of SW-M-I coupling tend to be low during the low Alfven Mach number period, from the event analysis of Nov. 2003 storm. Also, we have found that the Alfven Mach number dependence exists independently form the solar wind electric field dependence based on the statistical analysis of PCN index. Since the condition of low Alfven Mach number tend to occur within the ICMEs, we are developing the empirical model with considering the Alfven Mach number dependence. We expect this modification will improve the prediction of severe geomagnetic storm. We also try to examine that our model is valid during the period of recent few years of quiet solar activity.

  2. A Fluorescence-based Assay of Phospholipid Scramblase Activity.

    PubMed

    Ploier, Birgit; Menon, Anant K

    2016-01-01

    Scramblases translocate phospholipids across the membrane bilayer bidirectionally in an ATP-independent manner. The first scramblase to be identified and biochemically verified was opsin, the apoprotein of the photoreceptor rhodopsin. Rhodopsin is a G protein-coupled receptor localized in rod photoreceptor disc membranes of the retina where it is responsible for the perception of light. Rhodopsin's scramblase activity does not depend on its ligand 11-cis-retinal, i.e., the apoprotein opsin is also active as a scramblase. Although constitutive and regulated phospholipid scrambling play an important role in cell physiology, only a few phospholipid scramblases have been identified so far besides opsin. Here we describe a fluorescence-based assay of opsin's scramblase activity. Opsin is reconstituted into large unilamellar liposomes composed of phosphatidylcholine, phosphatidylglycerol and a trace quantity of fluorescent NBD-labeled PC (1-palmitoyl-2-{6-[7-nitro-2-1,3-benzoxadiazole-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine). Scramblase activity is determined by measuring the extent to which NBD-PC molecules located in the inner leaflet of the vesicle are able to access the outer leaflet where their fluorescence is chemically eliminated by a reducing agent that cannot cross the membrane. The methods we describe have general applicability and can be used to identify and characterize scramblase activities of other membrane proteins. PMID:27684510

  3. Toward Understanding the Molecular Bases of Stretch Activation

    PubMed Central

    Sanfelice, Domenico; Sanz-Hernández, Máximo; de Simone, Alfonso; Bullard, Belinda; Pastore, Annalisa

    2016-01-01

    Muscles are usually activated by calcium binding to the calcium sensory protein troponin-C, which is one of the three components of the troponin complex. However, in cardiac and insect flight muscle activation is also produced by mechanical stress. Little is known about the molecular bases of this calcium-independent activation. In Lethocerus, a giant water bug often used as a model system because of its large muscle fibers, there are two troponin-C isoforms, called F1 and F2, that have distinct roles in activating the muscle. It has been suggested that this can be explained either by differences in structural features or by differences in the interactions with other proteins. Here we have compared the structural and dynamic properties of the two proteins and shown how they differ. We have also mapped the interactions of the F2 isoform with peptides spanning the sequence of its natural partner, troponin-I. Our data have allowed us to build a model of the troponin complex and may eventually help in understanding the specialized function of the F1 and F2 isoforms and the molecular mechanism of stretch activation. PMID:27226601

  4. Human activity recognition based on human shape dynamics

    NASA Astrophysics Data System (ADS)

    Cheng, Zhiqing; Mosher, Stephen; Cheng, Huaining; Webb, Timothy

    2013-05-01

    Human activity recognition based on human shape dynamics was investigated in this paper. The shape dynamics describe the spatial-temporal shape deformation of a human body during its movement and thus provide important information about the identity of a human subject and the motions performed by the subject. The dynamic shapes of four subjects in five activities (digging, jogging, limping, throwing, and walking) were created via 3-D motion replication. The Paquet Shape Descriptor (PSD) was used to describe subject shapes in each frame. The principal component analysis was performed on the calculated PSDs and principal components (PCs) were used to characterize PSDs. The PSD calculation was then reasonably approximated by its significant projections in the eigen-space formed by PCs and represented by the corresponding projection coefficients. As such, the dynamic human shapes for each activity were described by these projection coefficients, which in turn, along with their derivatives were used to form the feature vectors (attribute sets) for activity classification. Data mining technology was employed with six classification methods used. Seven attribute sets were evaluated with high classification accuracy attained for most of them. The results from this investigation illustrate the great potential of human shape dynamics for activity recognition.

  5. Game-Based Virtual Worlds as Decentralized Virtual Activity Systems

    NASA Astrophysics Data System (ADS)

    Scacchi, Walt

    There is widespread interest in the development and use of decentralized systems and virtual world environments as possible new places for engaging in collaborative work activities. Similarly, there is widespread interest in stimulating new technological innovations that enable people to come together through social networking, file/media sharing, and networked multi-player computer game play. A decentralized virtual activity system (DVAS) is a networked computer supported work/play system whose elements and social activities can be both virtual and decentralized (Scacchi et al. 2008b). Massively multi-player online games (MMOGs) such as World of Warcraft and online virtual worlds such as Second Life are each popular examples of a DVAS. Furthermore, these systems are beginning to be used for research, deve-lopment, and education activities in different science, technology, and engineering domains (Bainbridge 2007, Bohannon et al. 2009; Rieber 2005; Scacchi and Adams 2007; Shaffer 2006), which are also of interest here. This chapter explores two case studies of DVASs developed at the University of California at Irvine that employ game-based virtual worlds to support collaborative work/play activities in different settings. The settings include those that model and simulate practical or imaginative physical worlds in different domains of science, technology, or engineering through alternative virtual worlds where players/workers engage in different kinds of quests or quest-like workflows (Jakobsson 2006).

  6. Dynamic positioning system based on active disturbance rejection technology

    NASA Astrophysics Data System (ADS)

    Lei, Zhengling; Guo, Chen; Fan, Yunsheng

    2015-08-01

    A dynamically positioned vessel, by the International Maritime Organization (IMO) and the certifying class societies (DNV, ABS, LR, etc.), is defined as a vessel that maintains its position and heading (fixed location or pre-determined track) exclusively by means of active thrusters. The development of control technology promotes the upgrading of dynamic positioning (DP) systems. Today there are two different DP systems solutions available on the market: DP system based on PID regulator and that based on model-based control. Both systems have limited disturbance rejection capability due to their design principle. In this paper, a new DP system solution is proposed based on Active Disturbance Rejection Control (ADRC) technology. This technology is composed of Tracking-Differentiator (TD), Extended State Observer (ESO) and Nonlinear Feedback Combination. On one hand, both TD and ESO can act as filters and can be used in place of conventional filters; on the other hand, the total disturbance of the system can be estimated and compensated by ESO, which therefore enhances the system's disturbance rejection capability. This technology's advantages over other methods lie in two aspects: 1) This method itself can not only achieve control objectives but also filter noisy measurements without other specialized filters; 2) This method offers a new useful approach to suppress the ocean disturbance. The simulation results demonstrate the effectiveness of the proposed method.

  7. Standardizing accelerometer-based activity monitor calibration and output reporting.

    PubMed

    Coolbaugh, Crystal L; Hawkins, David A

    2014-08-01

    Wearable accelerometer-based activity monitors (AMs) are used to estimate energy expenditure and ground reaction forces in free-living environments, but a lack of standardized calibration and data reporting methods limits their utility. The objectives of this study were to (1) design an inexpensive and easily reproducible AM testing system, (2) develop a standardized calibration method for accelerometer-based AMs, and (3) evaluate the utility of the system and accuracy of the calibration method. A centrifuge-type device was constructed to apply known accelerations (0-8g) to each sensitive axis of 30 custom and two commercial AMs. Accelerometer data were recorded and matrix algebra and a least squares solution were then used to determine a calibration matrix for the custom AMs to convert raw accelerometer output to units of g's. Accuracy was tested by comparing applied and calculated accelerations for custom and commercial AMs. AMs were accurate to within 4% of applied accelerations. The relatively inexpensive AM testing system (< $100) and calibration method has the potential to improve the sharing of AM data, the ability to compare data from different studies, and the accuracy of AM-based models to estimate various physiological and biomechanical quantities of interest in field-based assessments of physical activity.

  8. Autonomous star tracker based on active pixel sensors (APS)

    NASA Astrophysics Data System (ADS)

    Schmidt, U.

    2004-06-01

    Star trackers are opto-electronic sensors used onboard of satellites for the autonomous inertial attitude determination. During the last years, star trackers became more and more important in the field of the attitude and orbit control system (AOCS) sensors. High performance star trackers are based up today on charge coupled device (CCD) optical camera heads. The Jena-Optronik GmbH is active in the field of opto-electronic sensors like star trackers since the early 80-ties. Today, with the product family ASTRO5, ASTRO10 and ASTRO15, all marked segments like earth observation, scientific applications and geo-telecom are supplied to European and Overseas customers. A new generation of star trackers can be designed based on the APS detector technical features. The measurement performance of the current CCD based star trackers can be maintained, the star tracker functionality, reliability and robustness can be increased while the unit costs are saved.

  9. Startup and long term operation of enhanced biological phosphorus removal in continuous-flow reactor with granules.

    PubMed

    Li, Dong; Lv, Yufeng; Zeng, Huiping; Zhang, Jie

    2016-07-01

    The startup and long term operation of enhanced biological phosphorus removal (EBPR) in a continuous-flow reactor (CFR) with granules were investigated in this study. Through reducing the settling time from 9min to 3min gradually, the startup of EBPR in a CFR with granules was successfully realized in 16days. Under continuous-flow operation, the granules with good phosphorus and COD removal performance were stably operated for more than 6months. And the granules were characterized with particle size of around 960μm, loose structure and good settling ability. During the startup phase, polysaccharides (PS) was secreted excessively by microorganisms to resist the influence from the variation of operational mode. Results of relative quantitative PCR indicated that granules dominated by polyphosphate-accumulating organisms (PAOs) were easier accumulated in the CFR because more excellent settling ability was needed in the system.

  10. Startup and long term operation of enhanced biological phosphorus removal in continuous-flow reactor with granules.

    PubMed

    Li, Dong; Lv, Yufeng; Zeng, Huiping; Zhang, Jie

    2016-07-01

    The startup and long term operation of enhanced biological phosphorus removal (EBPR) in a continuous-flow reactor (CFR) with granules were investigated in this study. Through reducing the settling time from 9min to 3min gradually, the startup of EBPR in a CFR with granules was successfully realized in 16days. Under continuous-flow operation, the granules with good phosphorus and COD removal performance were stably operated for more than 6months. And the granules were characterized with particle size of around 960μm, loose structure and good settling ability. During the startup phase, polysaccharides (PS) was secreted excessively by microorganisms to resist the influence from the variation of operational mode. Results of relative quantitative PCR indicated that granules dominated by polyphosphate-accumulating organisms (PAOs) were easier accumulated in the CFR because more excellent settling ability was needed in the system. PMID:27085149

  11. Electrical conductivity as a state indicator for the start-up period of anaerobic fixed-bed reactors.

    PubMed

    Robles, A; Latrille, E; Ribes, J; Bernet, N; Steyer, J P

    2016-01-01

    The aim of this work was to analyse the applicability of electrical conductivity sensors for on-line monitoring the start-up period of an anaerobic fixed-bed reactor. The evolution of bicarbonate concentration and methane production rate was analysed. Strong linear relationships between electrical conductivity and both bicarbonate concentration and methane production rate were observed. On-line estimations of the studied parameters were carried out in a new start-up period by applying simple linear regression models, which resulted in a good concordance between both observed and predicted values. Electrical conductivity sensors were therefore identified as an interesting method for monitoring the start-up period of anaerobic fixed-bed reactors due to its reliability, robustness, easy operation, low cost, and minimum maintenance compared with the currently used sensors.

  12. Electrical conductivity as a state indicator for the start-up period of anaerobic fixed-bed reactors.

    PubMed

    Robles, A; Latrille, E; Ribes, J; Bernet, N; Steyer, J P

    2016-01-01

    The aim of this work was to analyse the applicability of electrical conductivity sensors for on-line monitoring the start-up period of an anaerobic fixed-bed reactor. The evolution of bicarbonate concentration and methane production rate was analysed. Strong linear relationships between electrical conductivity and both bicarbonate concentration and methane production rate were observed. On-line estimations of the studied parameters were carried out in a new start-up period by applying simple linear regression models, which resulted in a good concordance between both observed and predicted values. Electrical conductivity sensors were therefore identified as an interesting method for monitoring the start-up period of anaerobic fixed-bed reactors due to its reliability, robustness, easy operation, low cost, and minimum maintenance compared with the currently used sensors. PMID:27148733

  13. Ion Heating Characteristics of Merging/Reconnection Startup in MAST Spherical Tokamak Experiment

    NASA Astrophysics Data System (ADS)

    Tanabe, Hiroshi; Yamada, Takuma; Watanabe, Takenori; Gi, Keii; Kuwahata, Akihiro; Kadowaki, Kazutake; Kaminou, Yasuhiro; Koike, Hideya; Nishida, Kento; Imanaka, Suguru; Yamanaka, Haruki; You, Setthivoine; Crowley, Brendan; Conway, Neil; Scannel, Rory; Gryaznevich, Mikhail; Inomoto, Michiaki; Ono, Yasushi

    2014-10-01

    The high power reconnection heating has been investigated in MAST ST (spherical tokamak) merging startup experiment using a new 32-chords ion Doppler tomography diagnostics with optimized spatial resolution for the current sheet. The magnetic reconnection is observed to heat mostly ions in the downstream by the outflow and to heat electrons inside the current sheet. However, the high Te area is highly localized at the X-point probably due to the X line acceleration of electrons. Finally both of Ti and Te profiles are observed to form triple-peak structures after the ion-electron energy relaxation time τieE. The guide field does not affect ion heating under high guide field condition Bt > 3Brec , while it increases significantly the localized electron heating at the X point. The increment of ion temperature reaches ~200 eV in TS-3 and over ~1 keV in MAST, as predicted in the Brec2 (reconnecting field energy) scaling of reconnection heating. This scaling suggests the promising high Brec merging startup scenario for spherical tokamak.

  14. Efficiency arcjet thruster with controlled arc startup and steady state attachment

    NASA Technical Reports Server (NTRS)

    Smith, William W. (Inventor); Knowles, Steven C. (Inventor)

    1989-01-01

    An improved efficiency arcjet thruster has a constrictor and electrically-conductive nozzle anode defining an arc chamber, and an electrically-conductive rod having a tip spaced upstream from the constrictor and defining a cathode spaced from the anode by a gap generally coextensive with the arc chamber. An electrical potential is applied to the anode and cathode to generate an electrical arc in the arc chamber from the cathode to anode. Catalytically decomposed hydrazine is supplied to the arc chamber with generation of the arc so as to produce thermal heating and expansion thereof through the nozzle. The constrictor can have a electrically insulative portion disposed between the cathode tip and the nozzle anode, and an electrically-conductive anode extension disposed along the insulative portion so as to define an auxiliary gap with the cathode tip substantially smaller than the gap defined between the cathode and nozzle anode for facilitating startup of arc generation. The constrictor can also include an electrically-conductive electrode with a variable electrical potential to vary the shape of the arc generated in the arc chamber. Also, the cathode is mounted for axial movement such that the gap between its tip and the nozzle anode can be varied to facilitate a generally nonerosive generation of the electrical arc at startup and reliable steady state operation. Further, the arc chamber can have a nonparallel subsonic-to-supersonic transition configuration, or alternatively solely a nonparallel supersonic configuration, for improved arc attachment.

  15. Testing of a Loop Heat Pipe Subjective to Variable Accelerations. Part 1; Start-up

    NASA Technical Reports Server (NTRS)

    Ku, Jentung; Rogers, Paul; Hoff, Craig

    2000-01-01

    The effect of accelerating forces on the performance of loop heat pipes (LHP) is of interest and importance to terrestrial and space applications. They are being considered for cooling of military combat vehicles and for spinning spacecraft. In order to investigate the effect of an accelerating force on LHP operation, a miniature LHP was installed on a spin table. Variable accelerating forces were imposed on the LHP by spinning the table at different angular speeds. Several patterns of accelerating forces were applied, i.e. continuous spin at different speeds and periodic spin at different speeds and frequencies. The resulting accelerations ranged from 1.17 g's to 4.7 g's. This paper presents the first part of the experimental study, i.e. the effects of a centrifugal force on the LHP start-up. Tests were conducted by varying the heat load to the evaporator, sink temperature, magnitude and frequency of centrifugal force, and LHP orientation relative to the direction of the accelerating force. The accelerating force seems to have little effect on the loop start-up in terms of temperature overshoot and superheat at boiling incipience. Changes in these parameters seem to be stochastic with or without centrifugal accelerating forces. The LHP started successfully in all tests.

  16. Optical studies of the flow start-up processes in four convergent-divergent nozzles

    NASA Astrophysics Data System (ADS)

    Opalka, Klaus O.

    1991-03-01

    In the context of design studies for the U.S. Large Blast/Thermal Simulator, BRL has sponsored optical studies of the flow start-up in convergent-divergent nozzles which have the flow-initiating diaphragm located in the nozzle throat. The experiments were performed in the 200 mm shock tube at the Ernst-Mach Institute in Freiburg (Breisgau), West-Germany. The scope of the studies included divergent nozzles with half cone angles of 6, 16, 45 and 90 deg tested at seven diaphragm pressure ratios ranging from 4 to 188 and resulting in shock strengths ranging from 1.4 to 4.4. Results were summarized in graphs of significant parameters, e.g., shock formation time, flow start-up period, flow expansion angle, and shock strength versus the driver pressure ratio and further compared with numerical results obtained with the BRL-Q1D hydrocode. The numerical-experimental comparison shows qualitative agreement. The flow phenomena are generally reproduced by the computations as long as they are not strongly dependent on viscous effects. The study shows that a pressure loss of 10 percent is connected to the presence of a large area discontinuity at the exit plane of the nozzle throat when no divergent nozzle is attached. Results suggest that a 45 deg divergent nozzle may present an acceptable compromise for minimizing these pressure losses by reducing the associated area discontinuities.

  17. Design of a data-driven predictive controller for start-up process of AMT vehicles.

    PubMed

    Lu, Xiaohui; Chen, Hong; Wang, Ping; Gao, Bingzhao

    2011-12-01

    In this paper, a data-driven predictive controller is designed for the start-up process of vehicles with automated manual transmissions (AMTs). It is obtained directly from the input-output data of a driveline simulation model constructed by the commercial software AMESim. In order to obtain offset-free control for the reference input, the predictor equation is gained with incremental inputs and outputs. Because of the physical characteristics, the input and output constraints are considered explicitly in the problem formulation. The contradictory requirements of less friction losses and less driveline shock are included in the objective function. The designed controller is tested under nominal conditions and changed conditions. The simulation results show that, during the start-up process, the AMT clutch with the proposed controller works very well, and the process meets the control objectives: fast clutch lockup time, small friction losses, and the preservation of driver comfort, i.e., smooth acceleration of the vehicle. At the same time, the closed-loop system has the ability to reject uncertainties, such as the vehicle mass and road grade.

  18. Predicting Monoamine Oxidase Inhibitory Activity through Ligand-Based Models

    PubMed Central

    Vilar, Santiago; Ferino, Giulio; Quezada, Elias; Santana, Lourdes; Friedman, Carol

    2013-01-01

    The evolution of bio- and cheminformatics associated with the development of specialized software and increasing computer power has produced a great interest in theoretical in silico methods applied in drug rational design. These techniques apply the concept that “similar molecules have similar biological properties” that has been exploited in Medicinal Chemistry for years to design new molecules with desirable pharmacological profiles. Ligand-based methods are not dependent on receptor structural data and take into account two and three-dimensional molecular properties to assess similarity of new compounds in regards to the set of molecules with the biological property under study. Depending on the complexity of the calculation, there are different types of ligand-based methods, such as QSAR (Quantitative Structure-Activity Relationship) with 2D and 3D descriptors, CoMFA (Comparative Molecular Field Analysis) or pharmacophoric approaches. This work provides a description of a series of ligand-based models applied in the prediction of the inhibitory activity of monoamine oxidase (MAO) enzymes. The controlled regulation of the enzymes’ function through the use of MAO inhibitors is used as a treatment in many psychiatric and neurological disorders, such as depression, anxiety, Alzheimer’s and Parkinson’s disease. For this reason, multiple scaffolds, such as substituted coumarins, indolylmethylamine or pyridazine derivatives were synthesized and assayed toward MAO-A and MAO-B inhibition. Our intention is to focus on the description of ligand-based models to provide new insights in the relationship between the MAO inhibitory activity and the molecular structure of the different inhibitors, and further study enzyme selectivity and possible mechanisms of action. PMID:23231398

  19. Optimization of operation conditions for the startup of aerobic granular sludge reactors biologically removing carbon, nitrogen, and phosphorous.

    PubMed

    Lochmatter, Samuel; Holliger, Christof

    2014-08-01

    The transformation of conventional flocculent sludge to aerobic granular sludge (AGS) biologically removing carbon, nitrogen and phosphorus (COD, N, P) is still a main challenge in startup of AGS sequencing batch reactors (AGS-SBRs). On the one hand a rapid granulation is desired, on the other hand good biological nutrient removal capacities have to be maintained. So far, several operation parameters have been studied separately, which makes it difficult to compare their impacts. We investigated seven operation parameters in parallel by applying a Plackett-Burman experimental design approach with the aim to propose an optimized startup strategy. Five out of the seven tested parameters had a significant impact on the startup duration. The conditions identified to allow a rapid startup of AGS-SBRs with good nutrient removal performances were (i) alternation of high and low dissolved oxygen phases during aeration, (ii) a settling strategy avoiding too high biomass washout during the first weeks of reactor operation, (iii) adaptation of the contaminant load in the early stage of the startup in order to ensure that all soluble COD was consumed before the beginning of the aeration phase, (iv) a temperature of 20 °C, and (v) a neutral pH. Under such conditions, it took less than 30 days to produce granular sludge with high removal performances for COD, N, and P. A control run using this optimized startup strategy produced again AGS with good nutrient removal performances within four weeks and the system was stable during the additional operation period of more than 50 days.

  20. Tobacco Stem-Based Activated Carbons for High Performance Supercapacitors

    NASA Astrophysics Data System (ADS)

    Xia, Xiaohong; Liu, Hongbo; Shi, Lei; He, Yuede

    2012-09-01

    Tobacco stem-based activated carbons (TS-ACs) were prepared by simple KOH activation and their application as electrodes in the electrical double layer capacitor (EDLC) performed successfully. The BET surface area, pore volume, and pore size distribution of the TS-ACs were evaluated based on N2 adsorption isotherms at 77 K. The surface area of the obtained activated carbons varies over a wide range (1472.8-3326.7 m2/g) and the mesoporosity was enhanced significantly as the ratio of KOH to tobacco stem (TS) increased. The electrochemical behaviors of series TS-ACs were characterized by means of galvanostatic charging/discharging, cyclic voltammetry, and impedance spectroscopy. The correlation between electrochemical properties and pore structure was investigated. A high specific capacitance value as 190 F/g at 1 mA/cm2 was obtained in 1 M LiPF6-EC/DMC/DEC electrolyte solution. Furthermore, good performance is also achieved even at high current densities. A development of new use for TS into a valuable energy storage material is explored.

  1. Regulation of WRN helicase activity in human base excision repair.

    PubMed

    Ahn, Byungchan; Harrigan, Jeanine A; Indig, Fred E; Wilson, David M; Bohr, Vilhelm A

    2004-12-17

    Werner syndrome patients are deficient in the Werner protein (WRN), which is a multifunctional nuclear protein possessing 3'-5' exonuclease and ATP-dependent helicase activities. Studies of Werner syndrome cells and biochemical studies of WRN suggest that WRN plays a role in several DNA metabolic pathways. WRN interacts with DNA polymerase beta (pol beta) and stimulates pol beta strand displacement synthesis on a base excision repair (BER) intermediate in a helicase-dependent manner. In this report, we examined the effect of the major human apurinic/apyrimidinic endonuclease (APE1) and of pol beta on WRN helicase activity. The results show that WRN alone is able to unwind several single strand break BER intermediates. However, APE1 inhibits WRN helicase activity on these intermediates. This inhibition is likely due to the binding of APE1 to nicked apurinic/apyrimidinic sites, suggesting that APE1 prevents the promiscuous unwinding of BER intermediates. This inhibitory effect was relieved by the presence of pol beta. A model involving the pol beta-mediated hand-off of WRN protein is proposed based on these results.

  2. Enzymatic assay for calmodulins based on plant NAD kinase activity

    SciTech Connect

    Harmon, A.C.; Jarrett, H.W.; Cormier, M.J.

    1984-01-01

    NAD kinase with increased sensitivity to calmodulin was purified from pea seedlings (Pisum sativum L., Willet Wonder). Assays for calmodulin based on the activities of NAD kinase, bovine brain cyclic nucleotide phosphodiesterase, and human erythrocyte Ca/sup 2 -/-ATPase were compared for their sensitivities to calmodulin and for their abilities to discriminate between calmodulins from different sources. The activities of the three enzymes were determined in the presence of various concentrations of calmodulins from human erythrocyte, bovine brain, sea pansy (Renilla reniformis), mung bean seed (Vigna radiata L. Wilczek), mushroom (Agaricus bisporus), and Tetrahymena pyriformis. The concentrations of calmodulin required for 50% activation of the NAD kinase (K/sub 0.5/) ranged from 0.520 ng/ml for Tetrahymena to 2.20 ng/ml for bovine brain. The A/sub 0.5/ s ranged from 19.6 ng/ml for bovine brain calmodulin to 73.5 ng/ml for mushroom calmodulin for phosphodiesterase activation. The K/sub 0.5/'s for the activation of Ca/sup 2 +/-ATPase ranged from 36.3 ng/mol for erythrocyte calmodulin to 61.7 ng/ml for mushroom calmodulin. NAD kinase was not stimulated by phosphatidylcholine, phosphatidylserine, cardiolipin, or palmitoleic acid in the absence or presence of Ca/sup 2 +/. Palmitic acid had a slightly stimulatory effect in the presence of Ca/sup 2 +/ (10% of maximum), but no effect in the absence of Ca/sup 2 +/. Palmitoleic acid inhibited the calmodulin-stimulated activity by 50%. Both the NAD kinase assay and radioimmunoassay were able to detect calmodulin in extracts containing low concentrations of calmodulin. Estimates of calmodulin contents of crude homogenates determined by the NAD kinase assay were consistent with amounts obtained by various purification procedures. 30 references, 1 figure, 4 tables.

  3. Research on Social Stability Mechanisms Based on Activation Energy and Gradual Activation Reaction Theory

    NASA Astrophysics Data System (ADS)

    Ning, Miao; Gu, Jifa

    This paper draws a comparison between social stability and chemical reaction process, and brings forward the concept of “social temperature” and “activation energy of social agent”. It is considered that social temperature turns out to be the macro symptom of social average energy, and its unceasing up-climbing roots in the energy accumulation of “inferiorization” process of social system; that “activation energy of social agent” stands for the social energy or temperature where individuals or groups reach the limit of their psychological bearing ability. This paper, basing on above concepts, elaborates on and demonstrates the gradual activation reaction mechanisms of social stability by a lot of concrete examples. It is thought that there is a threshold value for social stability, and the society will be unstable if social temperature goes higher than this value; that the larger the social average activation energy is, the higher the temperature threshold value of social stability will be; and considering that different groups have different activation energy, those fragile groups with low activation energy are often the risk source which might pose a threat to social stability.

  4. Research-based active-learning instruction in physics

    NASA Astrophysics Data System (ADS)

    Meltzer, David E.; Thornton, Ronald K.

    2013-04-01

    The development of research-based active-learning instructional methods in physics has significantly altered the landscape of U.S. physics education during the past 20 years. Based on a recent review [D.E. Meltzer and R.K. Thornton, Am. J. Phys. 80, 478 (2012)], we define these methods as those (1) explicitly based on research in the learning and teaching of physics, (2) that incorporate classroom and/or laboratory activities that require students to express their thinking through speaking, writing, or other actions that go beyond listening and the copying of notes, or execution of prescribed procedures, and (3) that have been tested repeatedly in actual classroom settings and have yielded objective evidence of improved student learning. We describe some key features common to methods in current use. These features focus on (a) recognizing and addressing students' physics ideas, and (b) guiding students to solve problems in realistic physical settings, in novel and diverse contexts, and to justify or explain the reasoning they have used.

  5. Improved Active Harmonic Current Elimination Based on Voltage Detection

    PubMed Central

    Tan, Tianyuan; Dong, Shuan; Huang, Yingwei; Liu, Jian; Le, Jian; Liu, Kaipei

    2016-01-01

    With the increasing penetration of power electronic equipment in modern residential distribution systems, harmonics mitigation through the distributed generation (DG) interfacing converters has received significant attention. Among recently proposed methods, the so-called active resonance damper (ARD) and harmonic voltage compensator (HVC) based on voltage detection can effectively reduce the harmonic distortions in selected areas of distribution systems. However, it is found out that when traditional ARD algorithm is used to eliminate harmonic current injected by non-linear loads, its performance is constrained by stability problems and can at most eliminate half of the load harmonic currents. Thus, inspired by the duality between ARD and HVC, this paper presents a novel improved resistive active power filter (R-APF) algorithm based on integral-decoupling control. The design guideline for its parameters is then investigated through carefully analyzing the closed-loop poles’ trajectory. Computer studies demonstrate that the proposed algorithm can effectively mitigate the load harmonic currents and its performance is much better than traditional ARD based on proportional control. PMID:27295213

  6. Improved Active Harmonic Current Elimination Based on Voltage Detection.

    PubMed

    Tan, Tianyuan; Dong, Shuan; Huang, Yingwei; Liu, Jian; Le, Jian; Liu, Kaipei

    2016-01-01

    With the increasing penetration of power electronic equipment in modern residential distribution systems, harmonics mitigation through the distributed generation (DG) interfacing converters has received significant attention. Among recently proposed methods, the so-called active resonance damper (ARD) and harmonic voltage compensator (HVC) based on voltage detection can effectively reduce the harmonic distortions in selected areas of distribution systems. However, it is found out that when traditional ARD algorithm is used to eliminate harmonic current injected by non-linear loads, its performance is constrained by stability problems and can at most eliminate half of the load harmonic currents. Thus, inspired by the duality between ARD and HVC, this paper presents a novel improved resistive active power filter (R-APF) algorithm based on integral-decoupling control. The design guideline for its parameters is then investigated through carefully analyzing the closed-loop poles' trajectory. Computer studies demonstrate that the proposed algorithm can effectively mitigate the load harmonic currents and its performance is much better than traditional ARD based on proportional control. PMID:27295213

  7. Interfacial activation-based molecular bioimprinting of lipolytic enzymes.

    PubMed Central

    Mingarro, I; Abad, C; Braco, L

    1995-01-01

    Interfacial activation-based molecular (bio)-imprinting (IAMI) has been developed to rationally improve the performance of lipolytic enzymes in nonaqueous environments. The strategy combinedly exploits (i) the known dramatic enhancement of the protein conformational rigidity in a water-restricted milieu and (ii) the reported conformational changes associated with the activation of these enzymes at lipid-water interfaces, which basically involves an increased substrate accessibility to the active site and/or an induction of a more competent catalytic machinery. Six model enzymes have been assayed in several model reactions in nonaqueous media. The results, rationalized in light of the present biochemical and structural knowledge, show that the IAMI approach represents a straightforward, versatile method to generate manageable, activated (kinetically trapped) forms of lipolytic enzymes, providing under optimal conditions nonaqueous rate enhancements of up to two orders of magnitude. It is also shown that imprintability of lipolytic enzymes depends not only on the nature of the enzyme but also on the "quality" of the interface used as the template. PMID:7724558

  8. Predicting activity approach based on new atoms similarity kernel function.

    PubMed

    Abu El-Atta, Ahmed H; Moussa, M I; Hassanien, Aboul Ella

    2015-07-01

    Drug design is a high cost and long term process. To reduce time and costs for drugs discoveries, new techniques are needed. Chemoinformatics field implements the informational techniques and computer science like machine learning and graph theory to discover the chemical compounds properties, such as toxicity or biological activity. This is done through analyzing their molecular structure (molecular graph). To overcome this problem there is an increasing need for algorithms to analyze and classify graph data to predict the activity of molecules. Kernels methods provide a powerful framework which combines machine learning with graph theory techniques. These kernels methods have led to impressive performance results in many several chemoinformatics problems like biological activity prediction. This paper presents a new approach based on kernel functions to solve activity prediction problem for chemical compounds. First we encode all atoms depending on their neighbors then we use these codes to find a relationship between those atoms each other. Then we use relation between different atoms to find similarity between chemical compounds. The proposed approach was compared with many other classification methods and the results show competitive accuracy with these methods.

  9. An efficient start-up circuitry for de-energized ultra-low power energy harvesting systems

    NASA Astrophysics Data System (ADS)

    Hörmann, Leander B.; Berger, Achim; Salzburger, Lukas; Priller, Peter; Springer, Andreas

    2015-05-01

    Cyber-physical systems often include small wireless devices to measure physical quantities or control a technical process. These devices need a self-sufficient power supply because no wired infrastructure is available. Their operational time can be enhanced by energy harvesting systems. However, the convertible power is often limited and discontinuous which requires the need of an energy storage unit. If this unit (and thus the whole system) is de-energized, the start-up process may take a significant amount of time because of an inefficient energy harvesting process. Therefore, this paper presents a system which enables a safe and fast start-up from the de-energized state.

  10. Filmless versus film-based systems in radiographic examination costs: an activity-based costing method

    PubMed Central

    2011-01-01

    Background Since the shift from a radiographic film-based system to that of a filmless system, the change in radiographic examination costs and costs structure have been undetermined. The activity-based costing (ABC) method measures the cost and performance of activities, resources, and cost objects. The purpose of this study is to identify the cost structure of a radiographic examination comparing a filmless system to that of a film-based system using the ABC method. Methods We calculated the costs of radiographic examinations for both a filmless and a film-based system, and assessed the costs or cost components by simulating radiographic examinations in a health clinic. The cost objects of the radiographic examinations included lumbar (six views), knee (three views), wrist (two views), and other. Indirect costs were allocated to cost objects using the ABC method. Results The costs of a radiographic examination using a filmless system are as follows: lumbar 2,085 yen; knee 1,599 yen; wrist 1,165 yen; and other 1,641 yen. The costs for a film-based system are: lumbar 3,407 yen; knee 2,257 yen; wrist 1,602 yen; and other 2,521 yen. The primary activities were "calling patient," "explanation of scan," "take photographs," and "aftercare" for both filmless and film-based systems. The cost of these activities cost represented 36.0% of the total cost for a filmless system and 23.6% of a film-based system. Conclusions The costs of radiographic examinations using a filmless system and a film-based system were calculated using the ABC method. Our results provide clear evidence that the filmless system is more effective than the film-based system in providing greater value services directly to patients. PMID:21961846

  11. Chondroblastoma of the temporal base with high mitotic activity.

    PubMed

    Ishikawa, Eiichi; Tsuboi, Koji; Onizawa, Kojiro; Hara, Akira; Kusakari, Jun; Noguchi, Masayuki; Nose, Tadao

    2002-11-01

    A 24-year-old man presented with a rare chondroblastoma of the temporal base manifesting as local pain accompanied by difficulty in opening the mouth. Gross total removal was achieved at initial surgery, but the tumor demonstrated rapid and destructive regrowth from a very small residual volume without definite histological malignant transformation. Growth activity estimated by MIB-1 staining increased spontaneously from 2.5% at the initial operation to 18.7% at recurrence. Further extensive radical tumor removal by surgeons from multiple disciplines was performed. The patient has been free of recurrence for 3 years without radiotherapy. Chondroblastoma of the temporal bone is widely accepted as a benign tumor and regrowth after gross total removal is very rare. However, some cases of chondroblastoma have potentially high mitotic activity.

  12. In vitro antimicrobial activity of peroxide-based bleaching agents.

    PubMed

    Napimoga, Marcelo Henrique; de Oliveira, Rogério; Reis, André Figueiredo; Gonçalves, Reginaldo Bruno; Giannini, Marcelo

    2007-06-01

    Antibacterial activity of 4 commercial bleaching agents (Day White, Colgate Platinum, Whiteness 10% and 16%) on 6 oral pathogens (Streptococcus mutans, Streptococcus sobrinus, Streptococcus sanguinis, Candida albicans, Lactobacillus casei, and Lactobacillus acidophilus) and Staphylococcus aureus were evaluated. A chlorhexidine solution was used as a positive control, while distilled water was the negative control. Bleaching agents and control materials were inserted in sterilized stainless-steel cylinders that were positioned under inoculated agar plate (n = 4). After incubation according to the appropriate period of time for each microorganism, the inhibition zones were measured. Data were analyzed by 2-way analysis of variance and Tukey test (a = 0.05). All bleaching agents and the chlorhexidine solution produced antibacterial inhibition zones. Antimicrobial activity was dependent on peroxide-based bleaching agents. For most microorganisms evaluated, bleaching agents produced inhibition zones similar to or larger than that observed for chlorhexidine. C albicans, L casei, and L acidophilus were the most resistant microorganisms. PMID:17625621

  13. Chondroblastoma of the temporal base with high mitotic activity.

    PubMed

    Ishikawa, Eiichi; Tsuboi, Koji; Onizawa, Kojiro; Hara, Akira; Kusakari, Jun; Noguchi, Masayuki; Nose, Tadao

    2002-11-01

    A 24-year-old man presented with a rare chondroblastoma of the temporal base manifesting as local pain accompanied by difficulty in opening the mouth. Gross total removal was achieved at initial surgery, but the tumor demonstrated rapid and destructive regrowth from a very small residual volume without definite histological malignant transformation. Growth activity estimated by MIB-1 staining increased spontaneously from 2.5% at the initial operation to 18.7% at recurrence. Further extensive radical tumor removal by surgeons from multiple disciplines was performed. The patient has been free of recurrence for 3 years without radiotherapy. Chondroblastoma of the temporal bone is widely accepted as a benign tumor and regrowth after gross total removal is very rare. However, some cases of chondroblastoma have potentially high mitotic activity. PMID:12472218

  14. Laser-heating-based active optics for synchrotron radiation applications.

    PubMed

    Yang, Fugui; Li, Ming; Gao, Lidan; Sheng, Weifan; Liu, Peng; Zhang, Xiaowei

    2016-06-15

    Active optics has attracted considerable interest from researchers in synchrotron radiation facilities because of its capacity for x-ray wavefront correction. Here, we report a novel and efficient technique for correcting or modulating a mirror surface profile based on laser-heating-induced thermal expansion. An experimental study of the characteristics of the surface thermal deformation response indicates that the power of a milliwatt laser yields a bump height as low as the subnanometer scale and that the variation of the spot size modulates the response function width effectively. In addition, the capacity of the laser-heating technique for free-form surface modulation is demonstrated via a one-dimensional surface correction experiment. The developed method is a promising new approach toward effective x-ray active optics coupled with at-wavelength metrology techniques.

  15. In vitro antimicrobial activity of peroxide-based bleaching agents.

    PubMed

    Napimoga, Marcelo Henrique; de Oliveira, Rogério; Reis, André Figueiredo; Gonçalves, Reginaldo Bruno; Giannini, Marcelo

    2007-06-01

    Antibacterial activity of 4 commercial bleaching agents (Day White, Colgate Platinum, Whiteness 10% and 16%) on 6 oral pathogens (Streptococcus mutans, Streptococcus sobrinus, Streptococcus sanguinis, Candida albicans, Lactobacillus casei, and Lactobacillus acidophilus) and Staphylococcus aureus were evaluated. A chlorhexidine solution was used as a positive control, while distilled water was the negative control. Bleaching agents and control materials were inserted in sterilized stainless-steel cylinders that were positioned under inoculated agar plate (n = 4). After incubation according to the appropriate period of time for each microorganism, the inhibition zones were measured. Data were analyzed by 2-way analysis of variance and Tukey test (a = 0.05). All bleaching agents and the chlorhexidine solution produced antibacterial inhibition zones. Antimicrobial activity was dependent on peroxide-based bleaching agents. For most microorganisms evaluated, bleaching agents produced inhibition zones similar to or larger than that observed for chlorhexidine. C albicans, L casei, and L acidophilus were the most resistant microorganisms.

  16. Laser-heating-based active optics for synchrotron radiation applications.

    PubMed

    Yang, Fugui; Li, Ming; Gao, Lidan; Sheng, Weifan; Liu, Peng; Zhang, Xiaowei

    2016-06-15

    Active optics has attracted considerable interest from researchers in synchrotron radiation facilities because of its capacity for x-ray wavefront correction. Here, we report a novel and efficient technique for correcting or modulating a mirror surface profile based on laser-heating-induced thermal expansion. An experimental study of the characteristics of the surface thermal deformation response indicates that the power of a milliwatt laser yields a bump height as low as the subnanometer scale and that the variation of the spot size modulates the response function width effectively. In addition, the capacity of the laser-heating technique for free-form surface modulation is demonstrated via a one-dimensional surface correction experiment. The developed method is a promising new approach toward effective x-ray active optics coupled with at-wavelength metrology techniques. PMID:27304296

  17. Ontology-based improvement to human activity recognition

    NASA Astrophysics Data System (ADS)

    Tahmoush, David; Bonial, Claire

    2016-05-01

    Human activity recognition has often prioritized low-level features extracted from imagery or video over higher-level class attributes and ontologies because they have traditionally been more effective on small datasets. However, by including knowledge-driven associations between actions and attributes while recognizing the lower-level attributes with their temporal relationships, we can attempt a hybrid approach that is more easily extensible to much larger datasets. We demonstrate a combination of hard and soft features with a comparison factor that prioritizes one approach over the other with a relative weight. We then exhaustively search over the comparison factor to evaluate the performance of a hybrid human activity recognition approach in comparison to the base hard approach at 84% accuracy and the current state-of-the-art.

  18. Synthesis, characterization and biological activity of Schiff bases based on chitosan and arylpyrazole moiety.

    PubMed

    Salama, Hend E; Saad, Gamal R; Sabaa, Magdy W

    2015-08-01

    The Schiff bases of chitosan were synthesized by the reaction of chitosan with 3-(4-substituted-phenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde. The structure of the prepared chitosan derivatives was characterized by FT-IR spectroscopy, elemental analysis, and X-ray diffraction studies and thermogravimetric analysis (TG). The results show that the specific properties of Schiff bases of chitosan can be altered by modifying the molecular structures with proper substituent groups.TG results reveal that the thermal stability of the prepared chitosan Schiff bases was lower than chitosan. The activation energy of decomposition was calculated using Coats-Redfern model. The antimicrobial activity of chitosan and Schiff bases of chitosan were investigated against Streptococcus pneumonia, Bacillis subtilis, Escherichia coli (as examples of bacteria) and Aspergillus fumigatus, Geotricum candidum and Syncephalastrum recemosum (as examples of fungi). The results indicated that the antimicrobial activity of the Schiff bases was stronger than that of chitosan and was dependent on the substituent group. The activity of un-substituted arylpyrazole chitosan derivative toward the investigated bacteria and fungi species was better than the other derivatives. PMID:26067768

  19. Active Physics Problem Based Learning for High Schools

    NASA Astrophysics Data System (ADS)

    Eisenkraft, Arthur

    2006-12-01

    Active Physics bridges research and practice. This NSF supported curriculum project uses a 7E instructional model and a problem based learning approach. Students learn physics on a need to know basis as they construct solutions to challenges such as developing a sport that can be played on the moon, creating an appliance package for developing countries, designing a light and sound show, or building a museum exhibit. In addition to meeting the content requirements of an introductory physics course, there is also an emphasis on engineering design principles and on essential questions. The excitement and frustration of trying to bridge research and practice will be discussed.

  20. Using activity-based costing to guide strategic decision making.

    PubMed

    Dowless, R M

    1997-06-01

    Activity-based costing (ABC) is not widely used in the healthcare industry. Some healthcare provider organizations are considering ABC, however, because of its potential to improve resource management and thereby maximize efficiency. ABC supports better pricing practices through more accurate costing and can be used to identify underutilized resources as well as associated costs that can be reduced. ABC can be a useful tool for determining the cost of unused capacity and for making strategic management decisions that will reduce costs. PMID:10167847

  1. Pattern matching based active optical sorting of colloids/cells

    NASA Astrophysics Data System (ADS)

    Verma, R. S.; Dasgupta, R.; Ahlawat, S.; Kumar, N.; Uppal, A.; Gupta, P. K.

    2013-08-01

    We report active optical sorting of colloids/cells by employing a cross correlation based pattern matching technique for selection of the desired objects and thereafter sorting using dynamically controllable holographic optical traps. The problem of possible collision between the different sets of objects during sorting was avoided by raising one set of particles to a different plane. We also present the results obtained on using this approach for some representative applications such as sorting of silica particles of two different sizes, of closely packed colloids and of white blood cells and red blood cells from a mixture of the two.

  2. Affinity Adsorbents Based on Carriers Activated by Epoxy-compounds

    NASA Astrophysics Data System (ADS)

    Klyashchitskii, B. A.; Kuznetsov, P. V.

    1984-10-01

    The review is devoted to the synthesis and applications of affinity adsorbents based on carriers activated by epoxy-compounds. The methods for the introduction of epoxy-groups into carriers of different chemical types are discussed and conditions for the immobilisation of three-dimensional spacers and low-molecular-weight and polymeric ligands on carriers containing epoxy-groups are considered. Data are presented on the properties and applications of adsorbents of this type in affinity chromatography. The bibliography includes 144 references.

  3. 40 CFR 745.233 - Lead-based paint activities requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Lead-based paint activities...) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.233 Lead-based paint activities requirements. Lead-based...

  4. 40 CFR 745.233 - Lead-based paint activities requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Lead-based paint activities...) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.233 Lead-based paint activities requirements. Lead-based...

  5. 40 CFR 745.233 - Lead-based paint activities requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Lead-based paint activities...) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.233 Lead-based paint activities requirements. Lead-based...

  6. 40 CFR 745.233 - Lead-based paint activities requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Lead-based paint activities...) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.233 Lead-based paint activities requirements. Lead-based...

  7. 40 CFR 745.233 - Lead-based paint activities requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Lead-based paint activities...) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.233 Lead-based paint activities requirements. Lead-based...

  8. Understanding Time-driven Activity-based Costing.

    PubMed

    Sharan, Alok D; Schroeder, Gregory D; West, Michael E; Vaccaro, Alexander R

    2016-03-01

    Transitioning to a value-based health care system will require providers to increasingly scrutinize their outcomes and costs. Although there has been a great deal of effort to understand outcomes, cost accounting in health care has been a greater challenge. Currently the cost accounting methods used by hospitals and providers are based off a fee-for-service system. As resources become increasingly scarce and the health care system attempts to understand which services provide the greatest value, it will be critically important to understand the true costs of delivering a service. An understanding of the true costs of a particular service will help providers make smarter decisions on how to allocate and utilize resources as well as determine which activities are nonvalue added. Achieving value will require providers to have a greater focus on accurate outcome data as well as better methods of cost accounting. PMID:26889988

  9. Understanding Time-driven Activity-based Costing.

    PubMed

    Sharan, Alok D; Schroeder, Gregory D; West, Michael E; Vaccaro, Alexander R

    2016-03-01

    Transitioning to a value-based health care system will require providers to increasingly scrutinize their outcomes and costs. Although there has been a great deal of effort to understand outcomes, cost accounting in health care has been a greater challenge. Currently the cost accounting methods used by hospitals and providers are based off a fee-for-service system. As resources become increasingly scarce and the health care system attempts to understand which services provide the greatest value, it will be critically important to understand the true costs of delivering a service. An understanding of the true costs of a particular service will help providers make smarter decisions on how to allocate and utilize resources as well as determine which activities are nonvalue added. Achieving value will require providers to have a greater focus on accurate outcome data as well as better methods of cost accounting.

  10. Background Subtraction Based on Color and Depth Using Active Sensors

    PubMed Central

    Fernandez-Sanchez, Enrique J.; Diaz, Javier; Ros, Eduardo

    2013-01-01

    Depth information has been used in computer vision for a wide variety of tasks. Since active range sensors are currently available at low cost, high-quality depth maps can be used as relevant input for many applications. Background subtraction and video segmentation algorithms can be improved by fusing depth and color inputs, which are complementary and allow one to solve many classic color segmentation issues. In this paper, we describe one fusion method to combine color and depth based on an advanced color-based algorithm. This technique has been evaluated by means of a complete dataset recorded with Microsoft Kinect, which enables comparison with the original method. The proposed method outperforms the others in almost every test, showing more robustness to illumination changes, shadows, reflections and camouflage. PMID:23857259

  11. Lewis base activation of Lewis acids: development of a Lewis base catalyzed selenolactonization.

    PubMed

    Denmark, Scott E; Collins, William R

    2007-09-13

    The concept of Lewis base activation of Lewis acids has been applied to the selenolactonization reaction. Through the use of substoichiometric amounts of Lewis bases with "soft" donor atoms (S, Se, P) significant rate enhancements over the background reaction are seen. Preliminary mechanistic investigations have revealed the resting state of the catalyst as well as the significance of a weak Brønsted acid promoter.

  12. Cooperative wireless network control based health and activity monitoring system.

    PubMed

    Prakash, R; Ganesh, A Balaji; Girish, Siva V

    2016-10-01

    A real-time cooperative communication based wireless network is presented for monitoring health and activity of an end-user in their environment. The cooperative communication offers better energy consumption and also an opportunity to aware the current location of a user non-intrusively. The link between mobile sensor node and relay node is dynamically established by using Received Signal Strength Indicator (RSSI) and Link Quality Indicator (LQI) based on adaptive relay selection scheme. The study proposes a Linear Acceleration based Transmission Power Decision Control (LA-TPDC) algorithm to further enhance the energy efficiency of cooperative communication. Further, the occurrences of false alarms are carefully prevented by introducing three stages of sequential warning system. The real-time experiments are carried-out by using the nodes, namely mobile sensor node, relay nodes and a destination node which are indigenously developed by using a CC430 microcontroller integrated with an in-built transceiver at 868 MHz. The wireless node performance characteristics, such as energy consumption, Signal-Noise ratio (SNR), Bit Error Rate (BER), Packet Delivery Ratio (PDR) and transmission offset are evaluated for all the participated nodes. The experimental results observed that the proposed linear acceleration based transmission power decision control algorithm almost doubles the battery life time than energy efficient conventional cooperative communication. PMID:27562484

  13. Cooperative wireless network control based health and activity monitoring system.

    PubMed

    Prakash, R; Ganesh, A Balaji; Girish, Siva V

    2016-10-01

    A real-time cooperative communication based wireless network is presented for monitoring health and activity of an end-user in their environment. The cooperative communication offers better energy consumption and also an opportunity to aware the current location of a user non-intrusively. The link between mobile sensor node and relay node is dynamically established by using Received Signal Strength Indicator (RSSI) and Link Quality Indicator (LQI) based on adaptive relay selection scheme. The study proposes a Linear Acceleration based Transmission Power Decision Control (LA-TPDC) algorithm to further enhance the energy efficiency of cooperative communication. Further, the occurrences of false alarms are carefully prevented by introducing three stages of sequential warning system. The real-time experiments are carried-out by using the nodes, namely mobile sensor node, relay nodes and a destination node which are indigenously developed by using a CC430 microcontroller integrated with an in-built transceiver at 868 MHz. The wireless node performance characteristics, such as energy consumption, Signal-Noise ratio (SNR), Bit Error Rate (BER), Packet Delivery Ratio (PDR) and transmission offset are evaluated for all the participated nodes. The experimental results observed that the proposed linear acceleration based transmission power decision control algorithm almost doubles the battery life time than energy efficient conventional cooperative communication.

  14. A molecular beacon assay for measuring base excision repair activities.

    PubMed

    Maksimenko, Andrei; Ishchenko, Alexander A; Sanz, Guenhaël; Laval, Jacques; Elder, Rhoderick H; Saparbaev, Murat K

    2004-06-18

    The base excision repair (BER) pathway plays a key role in protecting the genome from endogenous DNA damage. Current methods to measure BER activities are indirect and cumbersome. Here, we introduce a direct method to assay DNA excision repair that is suitable for automation and industrial use, based on the fluorescence quenching mechanism of molecular beacons. We designed a single-stranded DNA oligonucleotide labelled with a 5'-fluorescein (F) and a 3'-Dabcyl (D) in which the fluorophore, F, is held in close proximity to the quencher, D, by the stem-loop structure design of the oligonucleotide. Following removal of the modified base or incision of the oligonucleotide, the fluorophore is separated from the quencher and fluorescence can be detected as a function of time. Several modified beacons have been used to validate the assay on both cell-free extracts and purified proteins. We have further developed the method to analyze BER in cultured cells. As described, the molecular beacon-based assay can be applied to all DNA modifications processed by DNA excision/incision repair pathways. Possible applications of the assay are discussed, including high-throughput real-time DNA repair measurements both in vitro and in living cells.

  15. Start-up of a spiral periphyton bioreactor (SPR) for removal of COD and the characteristics of the associated microbial community.

    PubMed

    Shangguan, Haidong; Liu, Junzhuo; Zhu, Yan; Tong, Zhengong; Wu, Yonghong

    2015-10-01

    Periphyton-based bioreactors are widely accepted for removing various pollutants from wastewater; however, the slow start-up and low efficiency in widely fluctuating temperatures limit its application. A spiral periphyton bioreactor (SPR) was developed and its COD removal capability and the associated microbial communities were investigated. This SPR can be easily backwashed to stimulate periphyton growth and efficiently remove COD at temperatures ranging from 4 to 30 °C. The species richness and evenness of the periphyton community increased during domestication, while its functional diversity and organic carbon metabolic vitality were higher after 30 days domestication. Cyanobacteria were the main components of the SPR and produced an aerobic environment, while Alphaproteobacteria, Betaproteobacteria, Gammaproteobacteria and Sphingobacteria were the microorganisms responsible for COD removal. This study provides valuable insights into changes in pivotal microorganisms of the periphyton community during domestication, and indicates that SPR is simple to operate and efficient in COD removal.

  16. Electro-active material (EAM) based bend sensors

    NASA Astrophysics Data System (ADS)

    LaComb, Ronald; LaComb, Julie

    2010-04-01

    The capability to accurately estimate strain and orientation of cables in an undersea environment is important for a multitude of applications. One way to estimate the positional location of a submersed cable is to utilize a network of distributed bend sensors providing inputs to a curve fitting algorithm. In this work commercially available bend sensors are characterized for small deflections. In addition proto-type devices are presented which can potentially improve device sensitivity. Commercially available bend sensors are based upon electro-active materials and variable resistance materials. Electro-active materials (EAM) are known for their actuator functionality but certain EAMs are capable of sensing as well. New advances in materials such as Ionic Polymer Metal Composites (IPMC) are proving suitable for quasi-static sensor applications. These sensors are low power, conformal and produce directionally dependent output voltages which are linearly proportional to deflection, with voltage polarity representative of the deflection direction. IPMCs are capable of being morphed for increased sensitivity. Variable resistivity sensors are based on smart epoxy polymer and carbon loaded inks. These sensors are inexpensive and conformal and unlike EAMs provide static measurements.

  17. Category-based induction from similarity of neural activation.

    PubMed

    Weber, Matthew J; Osherson, Daniel

    2014-03-01

    The idea that similarity might be an engine of inductive inference dates back at least as far as David Hume. However, Hume's thesis is difficult to test without begging the question, since judgments of similarity may be infected by inferential processes. We present a one-parameter model of category-based induction that generates predictions about arbitrary statements of conditional probability over a predicate and a set of items. The prediction is based on the unconditional probabilities and similarities that characterize that predicate and those items. To test Hume's thesis, we collected brain activation from various regions of the ventral visual stream during a categorization task that did not invite comparison of categories. We then calculated the similarity of those activation patterns using a simple measure of vectorwise similarity and supplied those similarities to the model. The model's outputs correlated well with subjects' judgments of conditional probability. Our results represent a promising first step toward confirming Hume's thesis; similarity, assessed without reference to induction, may well drive inductive inference.

  18. EC assisted start-up experiments reproduction in FTU and AUG for simulations of the ITER case

    SciTech Connect

    Granucci, G.; Ricci, D.; Farina, D.; Figini, L.; Cavinato, M.; Stober, J.; Tudisco, O.

    2014-02-12

    The breakdown and plasma start-up in ITER are well known issues studied in the last few years in many tokamaks with the aid of calculation based on simplified modeling. The thickness of ITER metallic wall and the voltage limits of the Central Solenoid Power Supply strongly limit the maximum toroidal electric field achievable (0.3 V/m), well below the level used in the present generation of tokamaks. In order to have a safe and robust breakdown, the use of Electron Cyclotron Power to assist plasma formation and current rump up has been foreseen. This has raised attention on plasma formation phase in presence of EC wave, especially in order to predict the required power for a robust breakdown in ITER. Few detailed theory studies have been performed up to nowadays, due to the complexity of the problems. A simplified approach, extended from that proposed in ref[1] has been developed including a impurity multispecies distribution and an EC wave propagation and absorption based on GRAY code. This integrated model (BK0D) has been benchmarked on ohmic and EC assisted experiments on FTU and AUG, finding the key aspects for a good reproduction of data. On the basis of this, the simulation has been devoted to understand the best configuration for ITER case. The dependency of impurity distribution content and neutral gas pressure limits has been considered. As results of the analysis a reasonable amount of power (1 - 2 MW) seems to be enough to extend in a significant way the breakdown and current start up capability of ITER. The work reports the FTU data reproduction and the ITER case simulations.

  19. Low-Aspect Tokamak Start-Up and Operational Current Limits in Cdx-U

    NASA Astrophysics Data System (ADS)

    Jones, Theodore George

    1995-01-01

    A new, small, low-aspect-ratio tokamak (LART), named the Current Drive Experiment-Upgrade (CDX-U), has been designed and built for the investigation and development of the LART configuration, as well as for the investigation of novel current drive methods. Recently, an inductive ohmic heating and current drive (OH) system, including a compact high-field OH transformer coil, was designed and installed in CDX-U, enabling the study of LART plasmas with higher plasma currents and temperatures. Electron cyclotron resonance heating (ECH) was used in CDX-U to assist plasma breakdown, allowing breakdown with low initial induced voltage. Plasma start-up was achieved with transmitted ECH power of approximately l% of the maximum coupled OH power, at loop voltages as low as 1 Volt, and in toroidal magnetic fields ranging by a factor of 2.5 in strength. The reduction in loop voltage necessary for start-up minimized large, induced eddy currents in the toroidally continuous vessel walls common to LARTs. Plasma start-up and control in the presence of these significant vessel eddy currents was demonstrated, an important achievement for LART operation. Calculated ohmic efficiency, in terms of the Ejima coefficient. C_{E} , compared favorably with that found in other tokamaks, yielding C_{E} >=q 0.3-0.4. An operational current limit was found during extensive CDX-U ohmic operation, corresponding to an MHD safety factor, q(a), of approximately 3.5, a new low demonstrated q-limit for an aspect ratio, A, of 1.6. Studies of magnetic fluctuations in a range of plasma current from 15 kA to 40 kA revealed a coherent, saturating, 10-15 kHz frequency mode, with a toroidal mode number of n = l and a poloidol mode number ranging from m = 1 to m = 3. Numerical stability analysis of a magnetic reconstruction of a typical discharge exhibiting this mode indicated ideal stability. Previous studies of this mode at the lower plasma currents showed the amplitude increasing dramatically as the safety

  20. Chemical Signaling and Functional Activation in Colloidosome-Based Protocells.

    PubMed

    Sun, Shiyong; Li, Mei; Dong, Faqin; Wang, Shengjie; Tian, Liangfei; Mann, Stephen

    2016-04-13

    An aqueous-based microcompartmentalized model involving the integration of partially hydrophobic Fe(III)-rich montmorillonite (FeM) clay particles as structural and catalytic building blocks for colloidosome membrane assembly, self-directed membrane remodeling, and signal-induced protocell communication is described. The clay colloidosomes exhibit size- and charge-selective permeability, and show dual catalytic functions involving spatially confined enzyme-mediated dephosphorylation and peroxidase-like membrane activity. The latter is used for the colloidosome-mediated synthesis and assembly of a temperature-responsive poly(N-isopropylacrylamide)(PNIPAM)/clay-integrated hybrid membrane. In situ PNIPAM elaboration of the membrane is coupled to a glucose oxidase (GOx)-mediated signaling pathway to establish a primitive model of chemical communication and functional activation within a synthetic "protocell community" comprising a mixed population of GOx-containing silica colloidosomes and alkaline phosphatase (ALP)-containing FeM-clay colloidosomes. Triggering the enzyme reaction in the silica colloidosomes gives a hydrogen peroxide signal that induces polymer wall formation in a coexistent population of the FeM-clay colloidosomes, which in turn generates self-regulated membrane-gated ALP-activity within the clay microcompartments. The emergence of new functionalities in inorganic colloidosomes via chemical communication between different protocell populations provides a first step toward the realization of interacting communities of synthetic functional microcompartments. PMID:26923794