Science.gov

Sample records for activity notes step-by-step

  1. PHOEBE - step by step manual

    NASA Astrophysics Data System (ADS)

    Zasche, P.

    2016-03-01

    An easy step-by-step manual of PHOEBE is presented. It should serve as a starting point for the first time users of PHOEBE analyzing the eclipsing binary light curve. It is demonstrated on one particular detached system also with the downloadable data and the whole procedure is described easily till the final trustworthy fit is being reached.

  2. Dissecting a complex neurosurgical illustration: step-by-step development.

    PubMed

    Suk, Ian

    2011-12-01

    Modern computer graphics software has enabled the medical illustrator to render very complex anatomy by composing many different layers of drawings simultaneously. This and the author's capacity to take an "editorial" approach to compress several chronological events into a single, comprehensive two-dimensional illustration are analyzed in a step-by-step process. Through a series of images, the article provides a visual synopsis of the development of an illustration for an extensive clinical case: total sacrectomy performed through an all-posterior approach. Originally given as a slide presentation at the American Association of Neurological Surgeons Theodore Kurze Lecture in April 2011, the article provides some detailed notes on the techniques the author used to develop a comprehensive neurosurgical illustration.

  3. Step-by-Step Visual Manuals: Design and Development

    ERIC Educational Resources Information Center

    Urata, Toshiyuki

    2004-01-01

    The types of handouts and manuals that are used in technology training vary. Some describe procedures in a narrative way without graphics; some employ step-by-step instructions with screen captures. According to Thirlway (1994), a training manual should be like a tutor that permits a student to learn at his own pace and gives him confidence for…

  4. Preface, Soil Science: A step-by-step analysis

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This book provides step-by-step procedures for soil professionals, without a lot of background theory. Chapters are targeted toward agricultural and environmental consultants, producers, students, teachers, government, and industry. Applied soil scientists gave input through a survey, which guided t...

  5. Green Schools Energy Project: A Step-by-Step Manual.

    ERIC Educational Resources Information Center

    Quigley, Gwen

    This publication contains a step-by-step guide for implementing an energy-saving project in local school districts: the installation of newer, more energy-efficient "T-8" fluorescent tube lights in place of "T-12" lights. Eleven steps are explained in detail: (1) find out what kind of lights the school district currently uses;…

  6. Leading Change Step-by-Step: Tactics, Tools, and Tales

    ERIC Educational Resources Information Center

    Spiro, Jody

    2010-01-01

    "Leading Change Step-by-Step" offers a comprehensive and tactical guide for change leaders. Spiro's approach has been field-tested for more than a decade and proven effective in a wide variety of public sector organizations including K-12 schools, universities, international agencies and non-profits. The book is filled with proven tactics for…

  7. Step-by-step growth of complex oxide microstructures

    SciTech Connect

    Datskos, Panos G.; Cullen, David A.; Sharma, Jaswinder K.

    2015-06-10

    The synthesis of complex and hybrid oxide microstructures is of fundamental interest and practical applications. However, the design and synthesis of such structures is a challenging task. We developed a solution phase process to synthesize complex silica and silica titania hybrid microstructures by exploiting the emulsion droplet based shape control and step by step growth. The strategy is robust and can be extended to make complex hybrid structures made of two or more materials while each having its own shape.

  8. A step-by-step methodology for enterprise interoperability projects

    NASA Astrophysics Data System (ADS)

    Chalmeta, Ricardo; Pazos, Verónica

    2015-05-01

    Enterprise interoperability is one of the key factors for enhancing enterprise competitiveness. Achieving enterprise interoperability is an extremely complex process which involves different technological, human and organisational elements. In this paper we present a framework to help enterprise interoperability. The framework has been developed taking into account the three domains of interoperability: Enterprise Modelling, Architecture and Platform and Ontologies. The main novelty of the framework in comparison to existing ones is that it includes a step-by-step methodology that explains how to carry out an enterprise interoperability project taking into account different interoperability views, like business, process, human resources, technology, knowledge and semantics.

  9. Writing a Simulation Scenario: A Step-By-Step Guide.

    PubMed

    Bambini, Deborah

    2016-02-01

    Simulation is becoming a widely used method of helping nurses learn and maintain competency in the clinical area for both staff educators in clinical settings and nursing faculty in academic settings. Designing an effective simulation experience requires thoughtful planning, knowledge of educational principles, and knowledge of best practices in both simulation and clinical practice. An evidence-based strategy for writing a simulation scenario for nurses and other health care providers in any setting is described. A step-by-step process is outlined that incorporates best practices. Examples and suggestions are provided to help readers create quality simulation experiences.

  10. ACSM Fitness Book: A Proven Step-By-Step Program from the Experts. Third Edition.

    ERIC Educational Resources Information Center

    American Coll. of Sports Medicine, Indianapolis, IN.

    This offers advice on the health benefits of regular physical activity. It includes a scientifically proven fitness test to determine one's starting point and monitor ongoing progress, offering step-by-step instructions, sample programs, and insights on nutrition, weight control, motivation, and overcoming setbacks. Seven chapters examine: (1)…

  11. SPAR-H Step-by-Step Guidance

    SciTech Connect

    April M. Whaley; Dana L. Kelly; Ronald L. Boring; William J. Galyean

    2012-06-01

    Step-by-step guidance was developed recently at Idaho National Laboratory for the US Nuclear Regulatory Commission on the use of the Standardized Plant Analysis Risk-Human Reliability Analysis (SPAR-H) method for quantifying Human Failure Events (HFEs). This work was done to address SPAR-H user needs, specifically requests for additional guidance on the proper application of various aspects of the methodology. This paper overviews the steps of the SPAR-H analysis process and highlights some of the most important insights gained during the development of the step-by-step directions. This supplemental guidance for analysts is applicable when plant-specific information is available, and goes beyond the general guidance provided in existing SPAR-H documentation. The steps highlighted in this paper are: Step-1, Categorizing the HFE as Diagnosis and/or Action; Step-2, Rate the Performance Shaping Factors; Step-3, Calculate PSF-Modified HEP; Step-4, Accounting for Dependence, and; Step-5, Minimum Value Cutoff.

  12. SPAR-H Step-by-Step Guidance

    SciTech Connect

    W. J. Galyean; A. M. Whaley; D. L. Kelly; R. L. Boring

    2011-05-01

    This guide provides step-by-step guidance on the use of the SPAR-H method for quantifying Human Failure Events (HFEs). This guide is intended to be used with the worksheets provided in: 'The SPAR-H Human Reliability Analysis Method,' NUREG/CR-6883, dated August 2005. Each step in the process of producing a Human Error Probability (HEP) is discussed. These steps are: Step-1, Categorizing the HFE as Diagnosis and/or Action; Step-2, Rate the Performance Shaping Factors; Step-3, Calculate PSF-Modified HEP; Step-4, Accounting for Dependence, and; Step-5, Minimum Value Cutoff. The discussions on dependence are extensive and include an appendix that describes insights obtained from the psychology literature.

  13. Step-by-step phacoemulsification training program for ophthalmology residents

    PubMed Central

    Yulan, Wang; Yaohua, Sheng; Jinhua, Tao; Min, Wang

    2013-01-01

    Aims: The aim was to analyze the learning curve of phacoemulsification (phaco) performed by residents without experience in performing extra-capsular cataract extraction (ECCE) in a step-by-step training program (SBSTP). Materials and Methods: Consecutive surgical records of phaco performed from March 2009 to Sept 2011 by four residents without previous ECCE experience were retrospectively reviewed. The completion rate of the first 30 procedures by each resident was calculated. The main intraoperative phaco parameter records for the first 30 surgeries by each resident were compared with those for their last 30 surgeries. Intraoperative complications in the residents’ procedures were also recorded and analyzed. Results: A total of 1013 surgeries were performed by residents. The completion rate for the first 30 phaco procedures was 79.2 ± 5.8%. The main reasons for halting the procedure were as follows: Anterior capsule tear, inability to crack the nucleus, and posterior capsular rupture during phaco or cortex removal. Cumulative dissipated energy of phaco power used during the surgeries was significantly less in the last 30 cases compared with the first 30 cases (30.10 ± 17.58 vs. 55.41 ± 37.59, P = 0.021). Posterior capsular rupture rate was 2.5 ± 1.2% in total (10.8 ± 4.2% in the first 30 cases and 1.7 ± 1.9% in the last 30 cases, P = 0.008; a statistically significant difference). Conclusion: The step-by-step training program might be a necessary process for a resident to transit from dependence to a self-supported operator. It is also an essential middle step between wet lab training to performing the entire phaco procedure on the patient both effectively and safely. PMID:24178407

  14. Acta Clinica Croatica: progress of a journal step by step.

    PubMed

    Ramljak, Gordana

    2014-03-01

    The journal Acta Clinica Croatica (ACC) was founded in 1962 under the title Anali Bolnice Dr. M. Stojanović. In 1995, the title of the journal was changed into its present form and ever since all papers have been published in English. In 2000, the electronic (online) edition of the ACC was released in addition to the print version. The paper presents development of the journal from 1962 to 2012 based on the analysis of the following SCOPUS citation index parameters: type and number of documents published in the journal; number of citations; and number of domestic and foreign authors. The studied period was analyzed in three time segments: the period from 1995 to 1999, the period from 2000 to 2006 and the period from 2007 to 2012. The same parameters were analyzed in the Web of Science/SCI-Expanded bibliographic and citation index for the 2007-2012 period. The increasing number of documents, authors (both domestic and foreign) and citations demonstrates gradual rise in the quality, visibility and impact of the journal. The fifty years of experience show that a goal, at first very distant and almost unachievable, may be reached by progressing step by step.

  15. Undertaking a literature review: a step-by-step approach.

    PubMed

    Cronin, Patricia; Ryan, Frances; Coughlan, Michael

    Nowadays, most nurses, pre- and post-qualification, will be required to undertake a literature review at some point, either as part of a course of study, as a key step in the research process, or as part of clinical practice development or policy. For student nurses and novice researchers it is often seen as a difficult undertaking. It demands a complex range of skills, such as learning how to define topics for exploration, acquiring skills of literature searching and retrieval, developing the ability to analyse and synthesize data as well as becoming adept at writing and reporting, often within a limited time scale. The purpose of this article is to present a step-by-step guide to facilitate understanding by presenting the critical elements of the literature review process. While reference is made to different types of literature reviews, the focus is on the traditional or narrative review that is undertaken, usually either as an academic assignment or part of the research process.

  16. The impact of strenuous group physical activity on mood states, personal views, body composition, and markers of myocardial damage in overweight/obese adults: the "Step-by-step Italy's coast to coast" trek.

    PubMed

    Mazzeschi, Claudia; Piana, Natalia; Capezzali, Daniela; Mommi, Antonella; Aiello, Cristina; Gatti, Michela; Romani, Giannermete; Buratta, Livia; Battistini, Dalila; Nasini, Giovanni; Reginato, Elisa; Urbani, Lorena; Pazzagli, Chiara; Ferri, Carla; Ambrosio, Giuseppe; De Feo, Pierpaolo

    2014-01-01

    It is clinically relevant to understand whether it is safe to recommend to trained overweight/obese people long-distance treks and whether these experiences could have a negative psychological impact or become even dangerous exposing the trekkers to the risk of clinically silent myocardial damage. To answer these questions we have performed a quantitative/qualitative study comparing the changes in mood profiles, personal views, body composition, and plasma troponin levels of 40 overweight/obese subjects with those of 36 healthy normal weight subjects after the participation in a trek of 388 km from the Adriatic to the Tyrrhenian seas trek: the "Step by step…Italy's coast to coast". The results of this study demonstrate that long-distance treks are a safe activity for trained overweight/obese people which should be recommended because they improve mood, health status, and the relationship of participants with themselves and with the regular practice of exercise with effects similar to those obtained by healthy normal weight subjects.

  17. Building Relationships Step by Step: One Teacher Leader's Journey

    ERIC Educational Resources Information Center

    Mangin, Melinda M.

    2010-01-01

    This case describes how Hannah, a new math specialist, strives to create a positive math culture in her elementary school. Along the way, she works to build relationships with the teachers and the school principal. The accompanying teaching notes facilitate analysis of the case from the perspective of professional relationships in schools.

  18. Practical and low cost whole-organism motility assay: A step-by-step protocol.

    PubMed

    Preston, Sarah; Jabbar, Abdul; Nowell, Cameron; Joachim, Anja; Ruttkowski, Baerbel; Cardno, Tony; Hofmann, Andreas; Gasser, Robin B

    2016-02-01

    Here, we provide a step-by-step protocol for a practical and low cost whole-organism assay for the screening of chemical compounds for activity against parasitic worms. This assay has considerable advantages over conventional methods, mainly in relation to ease of use, throughput, time and cost. It is readily suited to the screening of hundreds to thousands of compounds for subsequent hit-to-lead optimisation, and should be applicable to many different parasites and other organisms commensurate with the size of wells in the microtiter plates used for phenotypic screening.

  19. Convergence of step-by-step methods for non-linear integro-differential equations.

    NASA Technical Reports Server (NTRS)

    Mocarsky, W. L.

    1971-01-01

    The theory of consistent step-by-step methods for solving Volterra integral equations is extended to nonsingular Volterra integro-differential equations. It is shown that standard step-by-step algorithms for these more general equations are convergent. Several numerical examples are included.

  20. A Step-by-Step Teaching Technique for Teachers with Adult Students of Mathematics

    ERIC Educational Resources Information Center

    McDonald, Betty

    2013-01-01

    Step-by-step teaching is a researcher-designed innovative process that takes the adult learner, step-by-step, from his present level of understanding to the required level. The technique is based on well-researched and accepted pedagogical practices set in their psychological, sociological, and andragogical perspectives. Using a convenience sample…

  1. Group Treatment for Mothers of Incest Victims: A Step by Step Approach.

    ERIC Educational Resources Information Center

    Landis, Lynn L.; Wyre, Charles H.

    1984-01-01

    Describes a step-by-step group treatment approach for mothers of incestuous families. The ten sessions provide support, help mothers identify protective plans for their children, and teach alternatives for handling significant relationships. (JAC)

  2. Local Climate Action Framework: A Step-by-Step Implementation Guide

    EPA Pesticide Factsheets

    This guide provides step-by-step guidance and resources for local governments to plan, implement, and evaluate climate, energy, and sustainability projects/programs to reduce greenhouse gas emissions and adapt to climate change impacts.

  3. Sage Simulation Model for Technology Demonstration Convertor by a Step-by-Step Approach

    NASA Technical Reports Server (NTRS)

    Demko, Rikako; Penswick, L. Barry

    2006-01-01

    The development of a Stirling model using the 1-D Saga design code was completed using a step-by-step approach. This is a method of gradually increasing the complexity of the Saga model while observing the energy balance and energy losses at each step of the development. This step-by-step model development and energy-flow analysis can clarify where the losses occur, their impact, and suggest possible opportunities for design improvement.

  4. From Recombinant Expression to Crystals: A Step-by-Step Guide to GPCR Crystallography.

    PubMed

    Shukla, Arun K; Kumari, Punita; Ghosh, Eshan; Nidhi, Kumari

    2015-01-01

    G protein-coupled receptors (GPCRs) are the primary targets of drugs prescribed for many human pathophysiological conditions such as hypertension, allergies, schizophrenia, asthma, and various types of cancer. High-resolution structure determination of GPCRs has been a key focus area in GPCR biology to understand the basic mechanism of their activation and signaling and to materialize the long-standing dream of structure-based drug design on these versatile receptors. There has been tremendous effort at this front in the past two decades and it has culminated into crystal structures of 27 different receptors so far. The recent progress in crystallization and structure determination of GPCRs has been driven by innovation and cutting-edge developments at every step involved in the process of crystallization. Here, we present a step-by-step description of various steps involved in GPCR crystallization starting from recombinant expression to obtaining diffracting crystals. We also discuss the next frontiers in GPCR biology that are likely to be a primary focus for crystallography efforts in the next decade or so.

  5. A fragment based step-by-step strategy for determining the most stable conformers of biomolecules

    NASA Astrophysics Data System (ADS)

    Li, Hongbao; Lin, Zijing; Luo, Yi

    2014-08-01

    For biomolecules of increased size and flexibility, more efficient and reliable strategies are always needed to determine their stable low-energy conformers. Here, we propose a fragment based step-by-step strategy to search for the full conformational space of biomolecules. In this strategy, the molecule is divided into several fragments and each of them is systematically optimized in a step-by-step fashion. It can significantly reduce the computational cost without losing any accuracy as demonstrated by the conformer search of several representative di-/tri-/tetra-peptides. Such an approach will be very useful for finding the stable conformers of large biomolecules.

  6. Fostering Autonomy through Syllabus Design: A Step-by-Step Guide for Success

    ERIC Educational Resources Information Center

    Ramírez Espinosa, Alexánder

    2016-01-01

    Promoting learner autonomy is relevant in the field of applied linguistics due to the multiple benefits it brings to the process of learning a new language. However, despite the vast array of research on how to foster autonomy in the language classroom, it is difficult to find step-by-step processes to design syllabi and curricula focused on the…

  7. On the Road towards Child-Centered Education: Step by Step in Moldova

    ERIC Educational Resources Information Center

    Cincilei, Cornelia

    2010-01-01

    This article discusses the outcome of the implementation of the Step by Step child-centered education model in Moldova. The implementation began with 12 classrooms of four-to five-year-old children in five kindergartens. The positive response from parents and teachers received at the end of the first year exceeded all expectations. As a result, 60…

  8. Simple and Inexpensive CD-ROM Networking: A Step-by-Step Approach.

    ERIC Educational Resources Information Center

    Cain, Mark

    1993-01-01

    Describes a low-cost, upgradeable, CD-ROM network and gives a step-by-step description of the installation process, including inventorying assets, learning about network components, selecting a network, installing adapter boards, attaching cabling, installing software, testing, configuring the server, installing search software, installing a menu,…

  9. Portfolio Planner: A Step-by-Step Guide to Portfolio Assessment.

    ERIC Educational Resources Information Center

    Jasmine, Julia

    This guide presents a step-by-step portfolio assessment method for teachers who want to implement portfolio assessment in their classrooms. Portfolio assessment is not neat or tidy in its early stages, but tidy and organized portfolios can be constructed if the outlined steps are followed. These are: (1) storage and establishing a file for each…

  10. Organizing Community-Wide Dialogue for Action and Change: A Step-by-Step Guide.

    ERIC Educational Resources Information Center

    Campbell, Sarah vL.; Malick, Amy; Landesman, John; Barrett, Molly Holme; Leighninger, Matt; McCoy, Martha L.; Scully, Patrick L.

    This document is a step-by-step guide to organizing a study circle program to serve as a vehicle to achieve communitywide dialogue for action and change. Part 1 provides an overview of communitywide study circle programs, with special emphasis on their operation and impact. Part 2 details the following steps in organizing a communitywide study…

  11. The Step by Step Program: Linking Democracy and Early Childhood Education.

    ERIC Educational Resources Information Center

    Ford, Elizabeth; Coughlin, Pam

    1999-01-01

    Discusses the Step by Step Program, funded by the Open Society Institute (OSI) and operated in Eastern and Central Europe, former Soviet states, Haiti, and South Africa. Discusses OSI's belief that educating the youngest members of society in a way that encourages individualism, choice, initiative, and appreciation of differences can lead to a new…

  12. Listen to Me Listen to You: A Step-By-Step Guide to Communication Skills Training

    ERIC Educational Resources Information Center

    Kotzman, Mandy; Kotzman, Anne

    2008-01-01

    This step-by-step guide is a companion to the popular "Listen to Me, Listen to You: A Practical Guide to Self-Awareness, Communication Skills and Conflict Management" (New Expanded Edition, Penguin Books, 2007). It is designed for use by anyone working in communication skills and personal development training. Resource material is grouped under…

  13. SPSS for Windows Step by Step: A Simple Guide and Reference.

    ERIC Educational Resources Information Center

    George, Darren; Mallery, Paul

    This book is designed to give step-by-step instructions necessary to do most major types of data analysis using the Statistical Package for the Social Sciences (SPSS). SPSS is a powerful tool that is capable of conducting nearly any type of data analysis used in the social sciences. This book should enable the reader to do 95% of what the program…

  14. Integrated Marketing for Colleges, Universities, and Schools: A Step-by-Step Planning Guide.

    ERIC Educational Resources Information Center

    Sevier, Robert A.

    This book offers a step-by-step approach to marketing for educational institutions, especially colleges and universities. The book is organized into three broad sections. Section 1 makes the case for marketing in six chapters which address: (1) challenges which are or will affect colleges and universities; (2) the role of institutional mission,…

  15. How to Conduct Surveys: A Step-by-Step Guide. Sixth Edition

    ERIC Educational Resources Information Center

    Fink, Arlene

    2016-01-01

    Packed with new topics that reflect today's challenges, the Sixth Edition of the bestselling "How to Conduct Surveys" guides readers through the process of developing their own rigorous surveys and evaluating the credibility and transparency of surveys created by others. Offering practical, step-by-step advice and written in the same…

  16. Setting up a Library BBS: A Step-by-Step Guide.

    ERIC Educational Resources Information Center

    Williams, Gene; Mitchell, Chris

    1987-01-01

    Setting up a public library bulletin board system is described as a way to attract young adult users as well as to foster awareness and use of electronic information media. Step-by-step guidelines cover hardware needed, including modems, types of software available, designing the system's contents, and maintenance and security. (EM)

  17. A Step by Step Guide for Planning a Japanese Cultural Festival.

    ERIC Educational Resources Information Center

    Murphy, Carole

    Teachers at all academic levels can adapt the design and content of the sixth grade Japanese cultural festival detailed in this learning packet. Material is divided into 2 sections. Section 1 provides a step-by-step guide to planning and conducting the festival. These instructions, based on 5 years of experience, include a detailed planning…

  18. Step by step error assessment in braided river sediment budget using airborne LiDAR data

    NASA Astrophysics Data System (ADS)

    Lallias-Tacon, S.; Liébault, F.; Piégay, H.

    2014-06-01

    Sequential airborne LiDAR surveys were used to reconstruct the sediment budget of a 7-km-long braided river channel in southeastern France following a 14-year return period flood and to improve its accuracy step by step. Data processing involved (i) surface matching of the sequential point clouds, (ii) spatially distributed propagation of uncertainty based on surface conditions of the channel, and (iii) water depth subtraction from the digital elevation models based on water depths measured in the field. The respective influence of each processing step on sediment budget computation was systematically documented. This showed that surface matching and water depth subtraction both have a considerable effect on the net sediment budget. Although DEM of difference thresholding based on uncertainty analysis on absolute elevation values had a smaller effect on the sediment budget, this step is crucial for the production of a comprehensive map of channel deformations. A large independent data set of RTK-GPS checkpoints was used to control the quality of the LiDAR altimetry. The results showed that high density (7-9 points/m2) airborne LiDAR surveys can provide a very high level of detection of elevation changes on the exposed surfaces of the channel, with a 95% confidence interval level of detection between 19 and 30 cm. Change detection from LiDAR data revealed that 54% of the pre-flood active channel was reworked by the flood. The braided channel pattern was highly disturbed by the flood owing to the occurrence of several channel avulsions.

  19. Step-by-step guide to critiquing research. Part 1: quantitative research.

    PubMed

    Coughlan, Michael; Cronin, Patricia; Ryan, Frances

    When caring for patients, it is essential that nurses are using the current best practice. To determine what this is, nurses must be able to read research critically. But for many qualified and student nurses, the terminology used in research can be difficult to understand, thus making critical reading even more daunting. It is imperative in nursing that care has its foundations in sound research, and it is essential that all nurses have the ability to critically appraise research to identify what is best practice. This article is a step-by-step approach to critiquing quantitative research to help nurses demystify the process and decode the terminology.

  20. Step-by-step magic state encoding for efficient fault-tolerant quantum computation.

    PubMed

    Goto, Hayato

    2014-12-16

    Quantum error correction allows one to make quantum computers fault-tolerant against unavoidable errors due to decoherence and imperfect physical gate operations. However, the fault-tolerant quantum computation requires impractically large computational resources for useful applications. This is a current major obstacle to the realization of a quantum computer. In particular, magic state distillation, which is a standard approach to universality, consumes the most resources in fault-tolerant quantum computation. For the resource problem, here we propose step-by-step magic state encoding for concatenated quantum codes, where magic states are encoded step by step from the physical level to the logical one. To manage errors during the encoding, we carefully use error detection. Since the sizes of intermediate codes are small, it is expected that the resource overheads will become lower than previous approaches based on the distillation at the logical level. Our simulation results suggest that the resource requirements for a logical magic state will become comparable to those for a single logical controlled-NOT gate. Thus, the present method opens a new possibility for efficient fault-tolerant quantum computation.

  1. Step-by-step deposition of synthetic dopamine-eumelanin and metal cations.

    PubMed

    Ball, Vincent; Bour, Jérôme; Michel, Marc

    2013-09-01

    The photoprotection of skin depends mostly on a balance between two natural pigments: the black-brown eumelanin and the yellow-reddish pheomelanin. These pigments as well as their counterpart in the central nervous system, neuromelanin, interact strongly with metal cations like Fe(3+). In the mussel foot proteins, the coordination between catechol groups and these ions is also responsible for the strong hardness the mussel's cuticle. These examples are suggestive that coatings and materials can be made based on such materials, for instance, synthetic eumelanin colloids and metal cations. Herein, we demonstrate that films made from synthetic dopamine-eumelanin colloids and metal cations can be deposited on surfaces in a step-by-step manner. As typical metal cations, we used Cu(2+), Fe(3+), and La(3+) which are known to interact with eumelanins. In all cases, step-by-step deposition is only possible in the absence of water rinse between two deposition steps. It was found that trivalent cations allow for a faster increase in film deposition than Cu(2+). Complementary in PDADMAC-(eumelanin-Fe(3+))m films, iron III was found not to be reduced.

  2. Step-by-step mandibular reconstruction with free fibula flap modelling.

    PubMed

    Pellini, R; Mercante, G; Spriano, G

    2012-12-01

    The functional and aesthetic outcomes after segmental mandibular resection are closely related to the technique used during mandibular reconstruction with bone graft. The fibula free flap approach allows the possibility of using bone with/without skin for restoring the defect. Here, we aimed to establish the preplating technique for oromandibular reconstruction in a step-by-step fashion, based on 41 patients. The surgical technique is expounded in 8-10 steps. Preplating, plate removal, resection, replating, template modelling, contouring and fixation of the fibula represent the key points of the procedure. In this report, we show that the preplating and template modelling method is easy, does not incur extra costs and can be successfully used for mandibular reconstruction with bone graft. Functional and aesthetic results confirm the feasibility and reproducibility of the technique.

  3. [Web-based education: learning surgical procedures step-by-step with 3D visualization].

    PubMed

    van der Velde, Susanne; Maljers, Jaap; Wiggers, Theo

    2014-01-01

    There is a need for more uniform, structured education focused on surgical procedures. We offer a standardized, step-by-step, web-based procedural training method with which surgeons can train more interns efficiently. The basis of this learning method is formed by 3D films in which surgical procedures are performed in clearly defined steps and the anatomic structures behind the surgical operating planes are further dissected. This basis is supported by online modules in which, aside from the operation, preparation and postoperative care are also addressed. Registrars can test their knowledge with exams. Trainers can see what the registrars studied, how they scored and how they progressed with their clinical skills. With the online portfolio we offer building blocks for certification and accreditation. With this clearly structured research method of constant quality, registrars are less dependent on the local trainer. In addition, through better preparation, the operation capacity can be used more efficiently for the training.

  4. A Step-by-Step Clinical Approach for the Management of Neuroendocrine Tumours.

    PubMed

    Yordanova, A; Ahmadzadehfar, H; Gonzalez-Carmona, M; Strassburg, C; Mayer, K; Feldmann, G; Schmidt-Wolf, I; Lingohr, P; Fischer, S; Kristiansen, G; Essler, M

    2017-02-01

    Neuroendocrine tumours (NET) are rare neoplasms, but the incidence is permanently increasing. Most of the NETs are slow proliferating and clinically silent, and for that reason, they are often diagnosed at a stage with advanced disease. The complexity and diversity of the NET-biology require the treatment of patients in specialised centres to guarantee a qualified, multidisciplinary treatment planning. At our institution, we developed an interdisciplinary model for the assessment and treatment of NET. The aim was to adapt the guidelines to the clinical practice, exchange of current knowledge, and a tailored approach to the individual patient. In our team are included medical professionals from pathology, radiology, oncology, gastroenterology, oncological surgery, and nuclear medicine. In this paper, we describe step-by-step a procedural algorithm for the management of patients with neuroendocrine tumours, focusing on midgut-NETs in terms of therapy.

  5. Efficacy of a step-by-step carving technique for dental students.

    PubMed

    Kilistoff, Alan J; Mackenzie, Louis; D'Eon, Marcel; Trinder, Krista

    2013-01-01

    This study demonstrates the effectiveness of a step-by-step carving technique that is quickly and efficiently mastered by dental students. Thirty-six final-year dental students volunteered to participate in this study. The students were given pre-prepared lower right first molar simulation teeth that had the occlusal half replaced in carving wax. The study was conducted in three time phases: pre-test (Time 1), participative learning (Time 2), and post-test (Time 3). The pre-test had the students carve the wax with no instruction. Instruction and demonstration of the technique were given at Time 2, and the post-test had the students carve the tooth again with no guidance but with training. A statistically significant increase with a nearly medium effect size was found from Time 1 to Time 2. A statistically significant increase with a medium effect size was found when comparing Time 2 to Time 3. A statistically significant increase with a large effect size was found when comparing Time 1 to Time 3. This technique has proved to be an effective method of simultaneously teaching a large cohort of predoctoral dental students. The technique is consistent with constructivist learning theory.

  6. Step-by-Step Synthesis of Multimodule Assemblies Engineered from BODIPY, DPP, and Triphenylamine Moieties.

    PubMed

    Heyer, Elodie; Ziessel, Raymond

    2015-07-02

    In the present account we describe unsymmetrical triads constructed from extended borondipyrromethene (BODIPY) dyes, diketopyrrolopyrrole (DPP) dyes, and electron donor fragments based on triarylamine. The assemblages are such that each module maintains its individual optical and redox properties. The use of phenyl-alkyne-phenyl or phenyl-alkyne-thienyl spacer units is favorable for weak electronic interaction between the modules. The step-by-step linking of each module using palladium-catalyzed cross-coupling reactions provides both mono- and disubstituted derivatives, the latter obtained by passing in particular through a pivotal monosubstituted DPP building block with a reactive bromo substituent. Thus, grafting of a second dye occurs in a controlled manner, providing the target triads in good yields. This protocol allows also the synthesis of key intermediates and dyads, which appear useful for the understanding of the electrochemical and spectroscopic properties. All the dyes exhibit redox and optical properties suitable for cascade energy transfer and photoinduced electron transfer processes in appropriate solvents.

  7. Plasma-Assisted Growth of Silicon Nanowires by Sn Catalyst: Step-by-Step Observation

    NASA Astrophysics Data System (ADS)

    Tang, Jian; Maurice, Jean-Luc; Chen, Wanghua; Misra, Soumyadeep; Foldyna, Martin; Johnson, Erik V.; Roca i Cabarrocas, Pere

    2016-10-01

    A comprehensive study of the silicon nanowire growth process has been carried out. Silicon nanowires were grown by plasma-assisted-vapor-solid method using tin as a catalyst. We have focused on the evolution of the silicon nanowire density, morphology, and crystallinity. For the first time, the initial growth stage, which determines the nanowire (NW) density and growth direction, has been observed step by step. We provide direct evidence of the merging of Sn catalyst droplets and the formation of Si nanowires during the first 10 s of growth. We found that the density of Sn droplets decreases from 9000 Sn droplets/μm2 to 2000 droplets/μm2 after just 10 s of growth. Moreover, the long and straight nanowire density decreases from 170/μm2 after 2 min of growth to less than 10/μm2 after 90 min. This strong reduction in nanowire density is accompanied by an evolution of their morphology from cylindrical to conical, then to bend conical, and finally, to a bend inverted conical shape. Moreover, the changes in the crystalline structure of nanowires are from (i) monocrystalline to (ii) monocrystalline core/defective crystalline shell and then to (iii) monocrystalline core/defective crystalline shell/amorphous shell. The evolutions of NW properties have been explained in detail.

  8. A New Step-By-Step Aligner For Very Large Scale Integration (VLSI) Production

    NASA Astrophysics Data System (ADS)

    Mayer, Herbert E.; Loebach, Ernst W.

    1980-09-01

    Technological considerations of direct wafer stepping are examined and the requirements of high volume V.L.S.I. production are identified. An advanced step-and-repeat alignment system is presented which fulfills, to a high degree, the criteria developed. Its high numerical aperture 10:1 reduction lens provides high resolution at high contrast level. A new designed illumination system supplies high exposure intensity at excellent uniformity. An automatic step-by-step alignment, focusing and leveling system compensates for irregular wafer topography and its changes during processing. By the capability to follow images already present on the wafer, it allows cross-matching with other exposure systems used for less critical manufacturing steps. The through-the-lens system of feedback-controlled alignment and true focus recognition eliminates from the machine geometric and optical changes such as those caused by temperature variation. Means for protecting both reticle and wafer against such environmental influences as dust, temperature and vibrations are provided. Equipment design permits high throughput for a large variety of die formats. High productivity is achieved by microprocessor-controlled functions and automatic handling as well as specially developed high speed displacement devices. The instrument presented promises new levels of productivity and working line widths while drawing on current knowledge in resist technology and wafer processing.

  9. Step-by-Step Simulation of Radiation Chemistry Using Green Functions for Diffusion-Influenced Reactions

    NASA Technical Reports Server (NTRS)

    Plante, Ianik; Cucinotta, Francis A.

    2011-01-01

    Radiolytic species are formed approximately 1 ps after the passage of ionizing radiation through matter. After their formation, they diffuse and chemically react with other radiolytic species and neighboring biological molecules, leading to various oxidative damage. Therefore, the simulation of radiation chemistry is of considerable importance to understand how radiolytic species damage biological molecules [1]. The step-by-step simulation of chemical reactions is difficult, because the radiolytic species are distributed non-homogeneously in the medium. Consequently, computational approaches based on Green functions for diffusion-influenced reactions should be used [2]. Recently, Green functions for more complex type of reactions have been published [3-4]. We have developed exact random variate generators of these Green functions [5], which will allow us to use them in radiation chemistry codes. Moreover, simulating chemistry using the Green functions is which is computationally very demanding, because the probabilities of reactions between each pair of particles should be evaluated at each timestep [2]. This kind of problem is well adapted for General Purpose Graphic Processing Units (GPGPU), which can handle a large number of similar calculations simultaneously. These new developments will allow us to include more complex reactions in chemistry codes, and to improve the calculation time. This code should be of importance to link radiation track structure simulations and DNA damage models.

  10. A step-by-step regressed pediatric kidney depth formula validated by a reasonable index

    PubMed Central

    Hongwei, Si; Yingmao, Chen; Li, Li; Guangyu, Ma; Liuhai, Shen; Zhifang, Wu; Mingzhe, Shao; Sijin, Li

    2017-01-01

    Abstract In predicting pediatric kidney depth, we are especially interested in that the errors of most estimates are within a narrow range. Therefore, this study was intended to use the proportion of estimates within a range of −5 to 5 mm (P5 mm) to evaluate the formulas and tried to regress a kidney depth formula for children. The enrolled children aged from 1 to 19 years were randomly sampled into group A and group B (75% and 25% of all recruits, respectively). Using data of the group A, the test formula was regressed by nonlinear regression and subsequently Passing & Bablok regression, and validated in group B. The Raynaud, Gordon, Tonnesen, Taylor, and the test formulas were evaluated in the 2 groups. Accuracy was evaluated by bias, absolute bias, and P5 mm; and precision was evaluated by correlation coefficient. In addition, root-mean square error was used as a mixed index for both accuracy and precision. Body weight, height, and age did not have significant differences between the 2 groups. In the nonlinear regression, coefficients of the formula (kidney depth = a × weight/height + b × age) from group A were in narrower 95% confidence intervals. After the Passing & Bablok regression, biases of left and right kidney estimates were significantly decreased. In the evaluation of formulas, the test formula was obviously better than other formulas mentioned above, and P5 mm for left and right kidneys was about 60%. Among children younger than 10 years, P5 mm was even more than 70% for left and right kidney depths. To predict pediatric kidney depth, accuracy and precision of a step-by-step regressed formula were better than the 4 “standard” formulas. PMID:28353617

  11. Carrier Step-by-Step Transport Initiated by Precise Defect Distribution Engineering for Efficient Photocatalytic Hydrogen Generation.

    PubMed

    Chen, Jiewei; Wu, Gaoxiang; Wang, Tianyue; Li, Xiaodan; Li, Meicheng; Sang, Yuanhua; Liu, Hong

    2017-02-08

    Semiconductor photocatalysts have been widely used for solar-to-hydrogen conversion; however, efficient photocatalytic hydrogen generation still remains a challenge. To improve the photocatalytic activity, the critical step is the transport of photogenerated carriers from bulk to surface. Here, we report the carrier step-by-step transport (CST) for semiconductor photocatalysts through precise defect engineering. In CST, carriers can fast transport from bulk to shallow traps in the defective subsurface first, and then transfer to the surface active acceptors. The key challenge of initiating CST lies in fine controlling defect distribution in semiconductor photocatalysts to introduce the special band matching between the crystalline bulk and defect-controllable surface, moderate bridgelike shallow traps induced by subsurface defects, and abundant surface active sites induced by surface defects. In our proof-of-concept demonstration, the CST was introduced into typical semiconductor TiO2 assisted by the fluorine-assisted kinetic hydrolysis method, and the designed TiO2 can exhibit the state-of-the-art photocatalytic hydrogen generation rate among anatase TiO2 up to 13.21 mmol h(-1) g(-1), which is 120 times enhanced compared with crystalline anatase TiO2 under sunlight. The CST initiated by precise defect distribution engineering provides a new sight on greatly improving photocatalytic hydrogen generation performance of semiconductor catalysts.

  12. Highly efficient polymer solar cells by step-by-step optimizing donor molecular packing and acceptor redistribution.

    PubMed

    Sun, Qianqian; Zhang, Fujun; An, Qiaoshi; Zhang, Miao; Wang, Jian; Zhang, Jian

    2016-12-21

    The dynamic drying process of the active layer should play a vitally important role in determining the performance of polymer solar cells (PSCs). Donor molecular packing and acceptor redistribution can be optimized by two successive post-treatments on the active layer. The blend films were freshly prepared by spin-coating method and then immediately transferred to a covered glass Petri dish to allow self-assembly of the donor molecules. The films were then treated with methanol or PFN-methanol solution to adjust the acceptor redistribution. In this study, power conversion efficiencies (PCEs) of PSCs with PffBT4T-2OD:PC71BM as the active layer were improved from 6.74% to 8.75% by employing 80 min for self-assembly and 20 s of methanol soaking. The PCE was improved even further to 9.72% by inserting a PFN interfacial layer. The performance improvement was mainly attributed to the optimized PffBT4T-2OD molecular packing during the self-assembly process, ideal vertical phase separation driven by methanol soaking and efficient charge collection by insertion of a PFN interfacial layer. The molecular packing and vertical phase separation were characterized by grazing incidence X-ray diffraction (GIXD), transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS), respectively. The experimental results solidly supported the effectiveness of the step-by-step optimization strategy.

  13. Continuous versus step-by-step scanning mode of a novel 3D scanner for CyberKnife measurements.

    PubMed

    Al Kafi, M Abdullah; Mwidu, Umar; Moftah, Belal

    2015-11-01

    The purpose of the study is to investigate the continuous versus step-by-step scanning mode of a commercial circular 3D scanner for commissioning measurements of a robotic stereotactic radiosurgery system. The 3D scanner was used for profile measurements in step-by-step and continuous modes with the intent of comparing the two scanning modes for consistency. The profile measurements of in-plane, cross-plane, 15 degree, and 105 degree were performed for both fixed cones and Iris collimators at depth of maximum dose and at 10cm depth. For CyberKnife field size, penumbra, flatness and symmetry analysis, it was observed that the measurements with continuous mode, which can be up to 6 times faster than step-by-step mode, are comparable and produce scans nearly identical to step-by-step mode. When compared with centered step-by-step mode data, a fully processed continuous mode data gives rise to maximum of 0.50% and 0.60% symmetry and flatness difference respectfully for all the fixed cones and Iris collimators studied.

  14. A Spiral Step-by-Step Educational Method for Cultivating Competent Embedded System Engineers to Meet Industry Demands

    ERIC Educational Resources Information Center

    Jing,Lei; Cheng, Zixue; Wang, Junbo; Zhou, Yinghui

    2011-01-01

    Embedded system technologies are undergoing dramatic change. Competent embedded system engineers are becoming a scarce resource in the industry. Given this, universities should revise their specialist education to meet industry demands. In this paper, a spirally tight-coupled step-by-step educational method, based on an analysis of industry…

  15. Step by step simulation of phototubes for the KM3NeT and ANTARES optical modules

    NASA Astrophysics Data System (ADS)

    Hugon, Christophe M. F.

    2015-07-01

    This proceeding presents the step by step simulation of the ANTARES neutrino telescope and KM3NeT-it prototype optical modules. After a description of the physics goals and both the detectors, the aim of a detailed simulation of the optical module will be presented. The main results will be shown, together with its perspectives.

  16. Effective Questioning Strategies in the Classroom: A Step-by-Step Approach to Engaged Thinking and Learning, K-8

    ERIC Educational Resources Information Center

    Fusco, Esther

    2012-01-01

    Questions are the most important tool a teacher can use to build a community of thinkers. This practical guide provides teachers with a step-by-step process for implementing a set of questioning strategies known as the Questioning Cycle. This strategy supports teachers in planning and asking questions, assessing students' responses, and following…

  17. Data Wise: A Step by Step Guide to Using Assessment Results to Improve Teaching and Learning. Revised and Expanded Edition

    ERIC Educational Resources Information Center

    Boudett, Kathryn Parker, Ed.; City, Elizabeth A., Ed.; Murnane, Richard J., Ed.

    2013-01-01

    "Data Wise: A Step-by-Step Guide to Using Assessment Results to Improve Teaching and Learning" presents a clear and carefully tested blueprint for school leaders. It shows how examining test scores and other classroom data can become a catalyst for important schoolwide conversations that will enhance schools' abilities to capture…

  18. Perinatal Depression Algorithm: A Home Visitor Step-by-Step Guide for Advanced Management of Perinatal Depressive Symptoms

    ERIC Educational Resources Information Center

    Laszewski, Audrey; Wichman, Christina L.; Doering, Jennifer J.; Maletta, Kristyn; Hammel, Jennifer

    2016-01-01

    Early childhood professionals do many things to support young families. This is true now more than ever, as researchers continue to discover the long-term benefits of early, healthy, nurturing relationships. This article provides an overview of the development of an advanced practice perinatal depression algorithm created as a step-by-step guide…

  19. Parents Who Care: A Step-by-Step Guide for Families with Teens. [Video Included].

    ERIC Educational Resources Information Center

    Hawkins, J. David; Catalano, Richard F.

    The world can be a risky place for teenagers in the 1990s. This guide and videotape provide skills for parents who want to help teens move successfully through the steps from childhood to adulthood. Based on extensive research, each of the seven units in the guide includes advice, strategies, and activities for both parents and teens to improve…

  20. Looking for a Job: Step by Step = Buscando Trabajo: Paso por Paso.

    ERIC Educational Resources Information Center

    Edwards, Patricia

    This bilingual document provides guidelines and learning activities to assist migrant workers in looking for a job. The document covers the following areas: (1) a checklist providing an overview of job search skills; (2) developing a fact sheet of personal information; (3) listing good work qualities; (4) identifying references and securing…

  1. Selection of Yeasts as Starter Cultures for Table Olives: A Step-by-Step Procedure

    PubMed Central

    Bevilacqua, Antonio; Corbo, Maria Rosaria; Sinigaglia, Milena

    2012-01-01

    The selection of yeasts intended as starters for table olives is a complex process, including a characterization step at laboratory level and a validation at lab level and factory-scale. The characterization at lab level deals with the assessment of some technological traits (growth under different temperatures and at alkaline pHs, effect of salt, and for probiotic strains the resistance to preservatives), enzymatic activities, and some new functional properties (probiotic traits, production of vitamin B-complex, biological debittering). The paper reports on these traits, focusing both on their theoretical implications and lab protocols; moreover, there are some details on predictive microbiology for yeasts of table olives and on the use of multivariate approaches to select suitable starters. PMID:22666220

  2. Two-Dimensional Speckle Tracking of the Fetal Heart: A Practical Step-by-Step Approach for the Fetal Sonologist.

    PubMed

    DeVore, Greggory R; Polanco, Bardo; Satou, Gary; Sklansky, Mark

    2016-08-01

    Various approaches to 2-dimensional speckle tracking have been used to evaluate left ventricular function and deformation in the fetus, child, and adult. In 2015, because of differences in imaging devices and analytical programs, the cardiology community published a consensus document proposing standards for pediatric/adult deformation imaging using 2-dimensional speckle tracking. The understanding and application of deformation imaging in the fetus have been limited by a lack of uniform software, terminology, techniques, and display. This article provides a practical, step-by-step approach for deformation analysis of the fetal heart using offline software that is independent of specific ultrasound vendors.

  3. Diabetic foot and exercise therapy: step by step the role of rigid posture and biomechanics treatment.

    PubMed

    Francia, Piergiorgio; Gulisano, Massimo; Anichini, Roberto; Seghieri, Giuseppe

    2014-03-01

    Lower extremity ulcers represent a serious and costly complication of diabetes mellitus. Many factors contribute to the development of diabetic foot. Peripheral neuropathy and peripheral vascular disease are the main causes of foot ulceration and contribute in turn to the growth of additional risk factors such as limited joint mobility, muscular alterations and foot deformities. Moreover, a deficit of balance, posture and biomechanics can be present, in particular in patients at high risk for ulceration. The result of this process may be the development of a vicious cycle which leads to abnormal distribution of the foot's plantar pressures in static and dynamic postural conditions. This review shows that some of these risk factors significantly improve after a few weeks of exercise therapy (ET) intervention. Accordingly it has been suggested that ET can be an important weapon in the prevention of foot ulcer. The aim of ET can relate to one or more alterations typically found in diabetic patients, although greater attention should be paid to the evaluation and possible correction of body balance, rigid posture and biomechanics. Some of the most important limitations of ET are difficult access to therapy, patient compliance and the transitoriness of the results if the training stops. Many proposals have been made to overcome such limitations. In particular, it is important that specialized centers offer the opportunity to participate in ET and during the treatment the team should work to change the patient's lifestyle by improving the execution of appropriate daily physical activity.

  4. Middle Cerebral Artery Occlusion Model of Stroke in Rodents: A Step-by-Step Approach

    PubMed Central

    Shahjouei, Shima; Cai, Peter Y.; Ansari, Saeed; Sharififar, Sharareh; Azari, Hassan; Ganji, Sarah; Zand, Ramin

    2016-01-01

    Stroke is one of the leading causes of morbidity and mortality in developed countries and an immense amount of medical care resources are devoted to combat the poststroke debilitating consequences. The key to develop effective and clinically applicable treatment methodologies is a better understanding of the pathophysiology of the disease, including the root causes and targets for pharmacology. Developing these foundations requires the use of standard animal models that mimic the physicochemical process of the diseases that can reliably replicate results in order to test and fine-tune therapeutic modalities. Middle cerebral artery occlusion (MCAO), endothelin-1-induced ischemic stroke, photothrombosis, devascularization, embolization, and spontaneous infarction using hemorrhage are some examples of different animal models. Reliability of MCAO has been proved and due to the ability to induce reperfusion similar to tissue plasminogen activator (tPA) therapy, this model is widely used in preclinical studies. Here, we describe a detailed methodology on how to develop MCAO stroke in rodents using intra-arterial insertion of filament to occlude the middle cerebral artery. This approach allows for the study of a wide array of basic pathophysiology mechanisms, regenerative medicine and rehabilitation therapy. PMID:26958146

  5. Step by Step

    ERIC Educational Resources Information Center

    Walker, John

    2007-01-01

    There is a right way to clean a restroom. If a worker does two things wrong, repeated in 20 restrooms a day, it is fairly certain that restroom users will complain. However, what people see or smell is not the most important issue. The overriding guideline should be to clean for health first, appearance second. Minimizing…

  6. Step by Step

    ERIC Educational Resources Information Center

    Ruder, Robert

    2008-01-01

    Sometimes a principal just has to get out of the office. A walk around the building might provide an escape from the pace of a hectic day, a chance to clear the head and perhaps allow a new perspective on a seemingly monumental school-related challenge to emerge. Wherever the principal walks, he or she is able to identify things that need…

  7. ATMS Step By Step.

    ERIC Educational Resources Information Center

    National Library of Australia, Canberra.

    This manual is designed to provide an introduction and basic guide to the use of IBM's Advanced Text Management System (ATMS), the text processing system to be used for the creation of Australian data bases within AUSINET. Instructions are provided for using the system to enter, store, retrieve, and modify data, which may then be displayed at the…

  8. Security: Step by Step

    ERIC Educational Resources Information Center

    Svetcov, Eric

    2005-01-01

    This article provides a list of the essential steps to keeping a school's or district's network safe and sound. It describes how to establish a security architecture and approach that will continually evolve as the threat environment changes over time. The article discusses the methodology for implementing this approach and then discusses the…

  9. Starting a new residency program: a step-by-step guide for institutions, hospitals, and program directors.

    PubMed

    Barajaz, Michelle; Turner, Teri

    2016-01-01

    Although our country faces a looming shortage of doctors, constraints of space, funding, and patient volume in many existing residency programs limit training opportunities for medical graduates. New residency programs need to be created for the expansion of graduate medical education training positions. Partnerships between existing academic institutions and community hospitals with a need for physicians can be a very successful means toward this end. Baylor College of Medicine and The Children's Hospital of San Antonio were affiliated in 2012, and subsequently, we developed and received accreditation for a new categorical pediatric residency program at that site in 2014. We share below a step-by-step guide through the process that includes building of the infrastructure, educational development, accreditation, marketing, and recruitment. It is our hope that the description of this process will help others to spur growth in graduate medical training positions.

  10. Starting a new residency program: a step-by-step guide for institutions, hospitals, and program directors

    PubMed Central

    Barajaz, Michelle; Turner, Teri

    2016-01-01

    Although our country faces a looming shortage of doctors, constraints of space, funding, and patient volume in many existing residency programs limit training opportunities for medical graduates. New residency programs need to be created for the expansion of graduate medical education training positions. Partnerships between existing academic institutions and community hospitals with a need for physicians can be a very successful means toward this end. Baylor College of Medicine and The Children's Hospital of San Antonio were affiliated in 2012, and subsequently, we developed and received accreditation for a new categorical pediatric residency program at that site in 2014. We share below a step-by-step guide through the process that includes building of the infrastructure, educational development, accreditation, marketing, and recruitment. It is our hope that the description of this process will help others to spur growth in graduate medical training positions. PMID:27507541

  11. Methods to construct a step-by-step beginner’s guide to decision analytic cost-effectiveness modeling

    PubMed Central

    Rautenberg, Tamlyn; Hulme, Claire; Edlin, Richard

    2016-01-01

    Background Although guidance on good research practice in health economic modeling is widely available, there is still a need for a simpler instructive resource which could guide a beginner modeler alongside modeling for the first time. Aim To develop a beginner’s guide to be used as a handheld guide contemporaneous to the model development process. Methods A systematic review of best practice guidelines was used to construct a framework of steps undertaken during the model development process. Focused methods review supplemented this framework. Consensus was obtained among a group of model developers to review and finalize the content of the preliminary beginner’s guide. The final beginner’s guide was used to develop cost-effectiveness models. Results Thirty-two best practice guidelines were data extracted, synthesized, and critically evaluated to identify steps for model development, which formed a framework for the beginner’s guide. Within five phases of model development, eight broad submethods were identified and 19 methodological reviews were conducted to develop the content of the draft beginner’s guide. Two rounds of consensus agreement were undertaken to reach agreement on the final beginner’s guide. To assess fitness for purpose (ease of use and completeness), models were developed independently and by the researcher using the beginner’s guide. Conclusion A combination of systematic review, methods reviews, consensus agreement, and validation was used to construct a step-by-step beginner’s guide for developing decision analytical cost-effectiveness models. The final beginner’s guide is a step-by-step resource to accompany the model development process from understanding the problem to be modeled, model conceptualization, model implementation, and model checking through to reporting of the model results. PMID:27785080

  12. CT-Guided Percutaneous Step-by-Step Radiofrequency Ablation for the Treatment of Carcinoma in the Caudate Lobe

    PubMed Central

    Dong, Jun; Li, Wang; Zeng, Qi; Li, Sheng; Gong, Xiao; Shen, Lujun; Mao, Siyue; Dong, Annan; Wu, Peihong

    2015-01-01

    Abstract The location of the caudate lobe and its complex anatomy make caudate lobectomy and radiofrequency ablation (RFA) under ultrasound guidance technically challenging. The objective of the exploratory study was to introduce a novel modality of treatment of lesions in caudate lobe and discuss all details with our experiences to make this novel treatment modality repeatable and educational. The study enrolled 39 patients with liver caudate lobe tumor first diagnosed by computerized tomography (CT) or magnetic resonance imaging (MRI). After consultation of multi-disciplinary team, 7 patients with hepatic caudate lobe lesions were enrolled and accepted CT-guided percutaneous step-by-step RFA treatment. A total of 8 caudate lobe lesions of the 7 patients were treated by RFA in 6 cases and RFA combined with percutaneous ethanol injection (PEI) in 1 case. Median tumor diameter was 29 mm (range, 18–69 mm). A right approach was selected for 6 patients and a dorsal approach for 1 patient. Median operative time was 64 min (range, 59–102 min). Median blood loss was 10 mL (range, 8-16 mL) and mainly due to puncture injury. Median hospitalization time was 4 days (range, 2–5 days). All lesions were completely ablated (8/8; 100%) and no recurrence at the site of previous RFA was observed during median 8 months follow-up (range 3–11 months). No major or life-threatening complications or deaths occurred. In conclusion, percutaneous step-by-step RFA under CT guidance is a novel and effective minimally invasive therapy for hepatic caudate lobe lesions with well repeatability. PMID:26426638

  13. Cause-effect relationships concerning period-doubling bifurcations: step-by-step analysis of a complex system

    NASA Astrophysics Data System (ADS)

    Dejak, Camillo

    In this paper, the cause-effect relationships concerning the occurrence of the period-doubling bifurcation are analysed. Such analysis is carried out by investigating the dynamic of the simplest ODE systems. The governing equations of the system, in fact, contain only one non-linear term. Furthermore, the three state equations can be interpreted in ecological terms. The state equations were integrated using a purposely developed algorithm, based on a fourth order Taylor series expansion. This method allows one to follow the trajectories in a step-by-step detail and to compare the pre- and post-bifurcation ones. The results showed that the bifurcation is due to a very small change in the logarithmic derivative of the state variable which is directly affected by the non-linear term. This change cumulates over time and, in turn, affects the first two main variables, which can be taken as representative of the prey and predator density. The mechanism causes both, the detachment of the two limit cycles and their re-conjunction, after the next period. This finding is also interpreted in thermodynamic terms, by analysing the evolution of an entropy-like function. The above analysis showed that it is possible to detect early signs of bifurcation also for more complex systems and, in these cases, to identify the sub-set of state variables which is more affected by structural changes of the bifurcation dynamic of such systems.

  14. Facile synthesis and step by step enhancement of blue photoluminescence from Ag-doped ZnS quantum dots.

    PubMed

    Sahai, Sonal; Husain, Mushahid; Shanker, Virendra; Singh, Nahar; Haranath, D

    2011-05-15

    Our results pertaining to the step by step enhancement of photoluminescence (PL) intensity from ZnS:Ag,Al quantum dots (QDs) are presented. Initially, these QDs were synthesized using a simple co-precipitation technique involving a surfactant, polyvinylpyrrolidone (PVP), in de-ionised water. It was observed that the blue PL originated from ZnS:Ag,Al QDs was considerably weak and not suitable for any practical display application. Upon UV (365 nm) photolysis, the PL intensity augmented to ~170% and attained a saturation value after ~100 min of exposure. This is attributed to the photo-corrosion mechanism exerted by high-flux UV light on ZnS:Ag,Al QDs. Auxiliary enhancement of PL intensity to 250% has been evidenced by subjecting the QDs to high temperatures (200 °C) and pressures (~120 bars) in a sulphur-rich atmosphere, which is due to the improvement in crystallanity of ZnS QDs. The origin of the bright-blue PL has been discussed. The results were supported by X-ray phase analysis, high-resolution electron microscopy and compositional evaluation.

  15. IEA/WHO toolkit for WMSDs prevention: criteria and practical tools for a step by step approach.

    PubMed

    Occhipinti, Enrico; Colombini, Daniela

    2012-01-01

    When studying WMSDs, several determinants and their interrelationship are considered as relevant. Hence the necessity of an "holistic" approach to prevention, especially when preparing technical rules and strategic plans. There is a strong request, from OSH agencies and operators, for developing "simple" tools for risk assessment and management. In this context WHO asked IEA to develop a "Toolkit for WMSD prevention". The paper presents one of the main contribution to this WHO project, focused on selecting tools at different level for hazard identification, risk estimation and management. Proposals are based on two essential criteria: Acting on a step-by-step approach; Taking into account the presence of multiple influencing factors. The proposals consider: A Basic Step devoted to hazard identification by operative "key-enter" questions, that can be operated also by non-experts. A First Step, (quick assessment), for identifying 3 possible conditions: acceptable; high risk present; more detailed analysis (via tools presented at second step) necessary. This step can be operated by non-experts with only some specific training. A Second Step, where recognized (i.e. from international standards or guidelines) tools for risk estimation are used. This step can be operated only by persons with some specific training.

  16. Förster Energy Transport in Metal–Organic Frameworks Is Beyond Step-by-Step Hopping

    SciTech Connect

    Zhang, Qiongqiong; Zhang, Cankun; Cao, Lingyun; Wang, Zi; An, Bing; Lin, Zekai; Huang, Ruiyun; Zhang, Zhiming; Wang, Cheng; Lin, Wenbin

    2016-03-25

    Metal–organic frameworks (MOFs) with light-harvesting building blocks designed to mimic photosynthetic chromophore arrays in green plants provide an excellent platform to study exciton transport in networks with well-defined structures. A step-by-step exciton random hopping model made of the elementary steps of energy transfer between only the nearest neighbors is usually used to describe the transport dynamics. Although such a nearest neighbor approximation is valid in describing the energy transfer of triplet states via the Dexter mechanism, we found it inadequate in evaluating singlet exciton migration that occurs through the Förster mechanism, which involves one-step jumping over longer distance. We measured migration rates of singlet excitons on two MOFs constructed from truxene-derived ligands and zinc nodes, by monitoring energy transfer from the MOF skeleton to a coumarin probe in the MOF cavity. The diffusivities of the excitons on the frameworks were determined to be 1.8 × 10–2 cm2/s and 2.3 × 10–2 cm2/s, corresponding to migration distances of 43 and 48 nm within their lifetimes, respectively. “Through space” energy-jumping beyond nearest neighbor accounts for up to 67% of the energy transfer rates. This finding presents a new perspective in the design and understanding of highly efficient energy transport networks for singlet excited states.

  17. A step-by-step guide to non-linear regression analysis of experimental data using a Microsoft Excel spreadsheet.

    PubMed

    Brown, A M

    2001-06-01

    The objective of this present study was to introduce a simple, easily understood method for carrying out non-linear regression analysis based on user input functions. While it is relatively straightforward to fit data with simple functions such as linear or logarithmic functions, fitting data with more complicated non-linear functions is more difficult. Commercial specialist programmes are available that will carry out this analysis, but these programmes are expensive and are not intuitive to learn. An alternative method described here is to use the SOLVER function of the ubiquitous spreadsheet programme Microsoft Excel, which employs an iterative least squares fitting routine to produce the optimal goodness of fit between data and function. The intent of this paper is to lead the reader through an easily understood step-by-step guide to implementing this method, which can be applied to any function in the form y=f(x), and is well suited to fast, reliable analysis of data in all fields of biology.

  18. Application of a step-by-step fingerprinting identification method on a spilled oil accident in the Bohai Sea area

    NASA Astrophysics Data System (ADS)

    Sun, Peiyan; Gao, Zhenhui; Cao, Lixin; Wang, Xinping; Zhou, Qing; Zhao, Yuhui; Li, Guangmei

    2011-03-01

    In recent years, oil spill accidents occur frequently in the marine area of China. Finding out the spilled oil source is a key step in the relevant investigation. In this paper, a step-by-step fingerprinting identification method was used in a spilled oil accident in the Bohai Sea in 2002. Advanced chemical fingerprinting and data interpretation techniques were used to characterize the chemical composition and determine the possible sources of two spilled oil samples. The original gas chromatography -flame ionization detection (GC-FID) chromatogram of saturated hydrocarbons was compared. The gas chromatography-mass spectrometry (GC/MS) chromatograms of aromatic hydrocarbons terpane and sterane, n-alkane and poly-aromatic hydrocarbons (PAHs) were analyzed. The correlation analysis on diagnostic ratios was performed with Student's t-test. It is found that the oil fingerprinting of the spilled oil (designated as sz1) from the polluted sand beach was identical with the suspected oil (designated as ky1) from a nearby crude oil refinery factory. They both showed the fingerprinting character of mixed oil. The oil fingerprinting of the spilled oil (designated as ms1) collected from the port was significantly different from oil ky1 and oil sz1 and was with a lubricating oil fingerprint character. The identification result not only gave support for the spilled oil investigation, but also served as an example for studying spilled oil accidents.

  19. Creating Child-Centered Materials for Math and Science: 3-6 Year Olds. Step By Step: A Program for Children and Families.

    ERIC Educational Resources Information Center

    Stolberg, Judith Rothschild; Daniels, Ellen R.

    In child-centered education programs, children construct their own knowledge from their experiences and interactions with the world around them, and teachers foster children's growth and development by building on children's interests, needs, and strengths within a safe and caring environment. The Step by Step educational program developed a…

  20. Designing, Implementing, and Evaluating Social Skills Interventions for Elementary Students: Step-by-Step Procedures Based on Actual School-Based Investigations

    ERIC Educational Resources Information Center

    Lane, Kathleen Lynne; Menzies, Holly M.; Barton-Arwood, Sally M.; Doukas, Georgia L.; Munton, Sarah M.

    2005-01-01

    This article presents a step-by-step, empirically validated method for designing, implementing, and evaluating a formal social skills intervention based on specific skill deficits as identified by the Social Skills Rating System (SSRS; F. M. Gresham & S. N. Elliott, 1990). The 6 steps include: (1) identifying students for participation; (2)…

  1. Visual Aids Tracing Manual. Ideas and Step-By-Step Instructions for the Making of Hand-Drawn Filmstrips, Posters, and Flipcharts from Inexpensive Materials.

    ERIC Educational Resources Information Center

    World Neighbors, Inc., OKhoma City, OK.

    Designed to assist fieldworkers in constructing their own visual materials, this guide provides practical assistance for filmstrip production. The first of four sections presents step-by-step instructions for producing a polyvinyl filmstrip, including detailed directions for filmstrip construction, choice of materials, and hints for successful…

  2. Positive Classroom Management. A Step-by-Step Guide to Successfully Running the Show Without Destroying Student Dignity. 2nd Edition.

    ERIC Educational Resources Information Center

    DiGiulio, Robert

    This book provides K-12 teachers with concrete, step-by-step guidance on how to improve student behavior through positive classroom management. It explains how to take control of the classroom, offering an alternative to threats, rewards, and punishments. The book is divided into an introduction and three sections with seven chapters. The…

  3. Step-by-step guideline for disease-specific costing studies in low- and middle-income countries: a mixed methodology

    PubMed Central

    Hendriks, Marleen E.; Kundu, Piyali; Boers, Alexander C.; Bolarinwa, Oladimeji A.; te Pas, Mark J.; Akande, Tanimola M.; Agbede, Kayode; Gomez, Gabriella B.; Redekop, William K.; Schultsz, Constance; Tan, Siok Swan

    2014-01-01

    Background Disease-specific costing studies can be used as input into cost-effectiveness analyses and provide important information for efficient resource allocation. However, limited data availability and limited expertise constrain such studies in low- and middle-income countries (LMICs). Objective To describe a step-by-step guideline for conducting disease-specific costing studies in LMICs where data availability is limited and to illustrate how the guideline was applied in a costing study of cardiovascular disease prevention care in rural Nigeria. Design The step-by-step guideline provides practical recommendations on methods and data requirements for six sequential steps: 1) definition of the study perspective, 2) characterization of the unit of analysis, 3) identification of cost items, 4) measurement of cost items, 5) valuation of cost items, and 6) uncertainty analyses. Results We discuss the necessary tradeoffs between the accuracy of estimates and data availability constraints at each step and illustrate how a mixed methodology of accurate bottom-up micro-costing and more feasible approaches can be used to make optimal use of all available data. An illustrative example from Nigeria is provided. Conclusions An innovative, user-friendly guideline for disease-specific costing in LMICs is presented, using a mixed methodology to account for limited data availability. The illustrative example showed that the step-by-step guideline can be used by healthcare professionals in LMICs to conduct feasible and accurate disease-specific cost analyses. PMID:24685170

  4. Step-by-step strategy for protein enrichment and proteome characterisation of extracellular polymeric substances in wastewater treatment systems.

    PubMed

    Silva, Ana F; Carvalho, Gilda; Soares, Renata; Coelho, Ana V; Barreto Crespo, M Teresa

    2012-08-01

    Extracellular polymeric substances (EPS) are keys in biomass aggregation and settleability in wastewater treatment systems. In membrane bioreactors (MBR), EPS are an important factor as they are considered to be largely responsible for membrane fouling. Proteins were shown to be the major component of EPS produced by activated sludge and to be correlated with the properties of the sludge, like settling, hydrophobicity and cell aggregation. Previous EPS proteomic studies of activated sludge revealed several problems, like the interference of other EPS molecules in protein analysis. In this study, a successful strategy was outlined to identify the proteins from soluble and bound EPS extracted from activated sludge of a lab-scale MBR. EPS samples were first subjected to pre-concentration through lyophilisation, centrifugal ultrafiltration or concentration with a dialysis membrane coated by a highly absorbent powder of polyacrylate-polyalcohol, preceded or not by a dialysis step. The highest protein concentration factors were achieved with the highly absorbent powder method without previous dialysis step. Four protein precipitation methods were then tested: acetone, trichloroacetic acid (TCA), perchloric acid and a commercial kit. Protein profiles were compared in 4-12 % sodium dodecyl sulphate polyacrylamide gel electrophoresis gels. Both acetone and TCA should be applied for the highest coverage for soluble EPS proteins, whereas TCA was the best method for bound EPS proteins. All visible bands of selected profiles were subjected to mass spectrometry analysis. A high number of proteins (25-32 for soluble EPS and 17 for bound EPS) were identified. As a conclusion of this study, a workflow is proposed for the successful proteome characterisation of soluble and bound EPS from activated sludge samples.

  5. The anatomy and art of writing a successful grant application: a practical step-by-step approach.

    PubMed

    Gholipour, Ali; Lee, Edward Y; Warfield, Simon K

    2014-12-01

    Writing a compelling grant application is a skill that is crucial to conducting high-quality and high-impact scientific research. A successful grant proposal provides the resources necessary to foster activity in an important area of investigation. A concise and practical overview of the anatomy and art of grant writing is provided in this article, along with citations to resources that are particularly useful for junior investigators.

  6. Step-by-step synchronous variations of planetary natural processes in 1997-1998 and their uniform mechanism: phenomenon of "galloping of the core"

    NASA Astrophysics Data System (ADS)

    Barkin, Yu. V.

    2009-04-01

    "For an explanation of observably step-by-step variations of geodynamic and geophysical processes the mechanism of sharp sporadic relative displacements of the core and the mantle and deformations of the mantle in the certain periods of time (the phenomenon of "galloping of the core") is offered. Apparently, this mechanism results in spasmodic variations of axial rotation of the Earth, causes gallop in value of a phase of Chandler motion of a pole, to sharp changes of the intense condition in zones of catastrophes" ([1], p. 61). According to geodynamic model the step changes first of all should to be observed in motion of a geocenter as it reflects relative displacement of the centers of mass of the core and the mantle [1]. A gallop of natural processes in northern and southern hemispheres is characterized by the certain asymmetry. In result the step changes are tested by trend components of secular changes of parameters. In another words and activity (intensity) and trends of its secular changes test synchronous certain steps. Geocenter. According to observation data of DORIS spasmodic changes of polar rotation of a geocenter in a projection to an equatorial coordinate plane in 1997-1999 are revealed. On data DORIS in values of polar coordinate of a geocenter were observed gallop up to 20-30 cm. Changes of trend components have tested gallop which can be estimated in -2 mm in coordinate x, -5 mm in coordinate y and in -10 mm in coordinate z. Trajectory of a geocenter. A bend of a trajectory of long - periodic trend "trace" of a geocenter (its epicentre) on a surface of the Earth in 1997-1998 has been discovered (Zotov, Barkin, Lyubushin, 2008). It serves as direct confirmation of the assumption about a fundamental role of interaction and the forced relative displacements of the basic shells of the Earth, first of all the core and the mantle, both their stimulating and directing role in all planetary processes (Barkin, 2002). Gravitational field. On the data of

  7. Penn Center for Community Health Workers: Step-by-Step Approach to Sustain an Evidence-Based Community Health Worker Intervention at an Academic Medical Center.

    PubMed

    Morgan, Anna U; Grande, David T; Carter, Tamala; Long, Judith A; Kangovi, Shreya

    2016-11-01

    Community-engaged researchers who work with low-income communities can be reliant on grant funding. We use the illustrative case of the Penn Center for Community Health Workers (PCCHW) to describe a step-by-step framework for achieving financial sustainability for community-engaged research interventions. PCCHW began as a small grant-funded research project but followed an 8-step framework to engage both low-income patients and funders, determine outcomes, and calculate return on investment. PCCHW is now fully funded by Penn Medicine and delivers the Individualized Management for Patient-Centered Targets (IMPaCT) community health worker intervention to 2000 patients annually.

  8. Assembly and benign step-by-step post-treatment of oppositely charged reduced graphene oxides for transparent conductive thin films with multiple applications.

    PubMed

    Zhu, Jiayi; He, Junhui

    2012-06-07

    We report a new approach for the fabrication of flexible and transparent conducting thin films via the layer-by-layer (LbL) assembly of oppositely charged reduced graphene oxide (RGO) and the benign step-by-step post-treatment on substrates with a low glass-transition temperature, such as glass and poly(ethylene terephthalate) (PET). The RGO dispersions and films were characterized by means of atomic force microscopy, UV-visible absorption spectrophotometery, Raman spectroscopy, transmission electron microscopy, contact angle/interface systems and a four-point probe. It was found that the graphene thin films exhibited a significant increase in electrical conductivity after the step-by-step post-treatments. The graphene thin film on the PET substrate had a good conductivity retainability after multiple cycles (30 cycles) of excessively bending (bending angle: 180°), while tin-doped indium oxide (ITO) thin films on PET showed a significant decrease in electrical conductivity. In addition, the graphene thin film had a smooth surface with tunable wettability.

  9. Microwave assisted step-by-step process for the production of fucoidan, alginate sodium, sugars and biochar from Ascophyllum nodosum through a biorefinery concept.

    PubMed

    Yuan, Yuan; Macquarrie, Duncan J

    2015-12-01

    The biorefinery is an important concept for the development of alternative routes to a range of interesting and important materials from renewable resources. It ensures that the resources are used fully and that all parts of them are valorized. This paper develops this concept, using brown macroalgae Ascophyllum nodosum as an example, by assistance of microwave technology. A step-by-step process was designed to obtain fucoidan, alginates, sugars and biochar (alga residue) consecutively. The yields of fucoidan, alginates, sugars and biochar were 14.09%, 18.24%, 10.87% and 21.44%, respectively. To make an evaluation of the biorefinery process, seaweed sample was also treated for fucoidan extraction only, alginate extraction only and hydrothermal treatment for sugars and biochar only. The chemical composition and properties of each product were also analyzed. The results indicated that A. nodosum could be potentially used as feedstock for a biorefinery process to produce valuable chemicals and fuels.

  10. Step-by-step protocol to perfuse and dissect the mouse parotid gland and isolation of high-quality RNA from murine and human parotid tissue.

    PubMed

    Watermann, Christoph; Valerius, Klaus Peter; Wagner, Steffen; Wittekindt, Claus; Klussmann, Jens Peter; Baumgart-Vogt, Eveline; Karnati, Srikanth

    2016-04-01

    Macroscopic identification and surgical removal of the mouse parotid gland is demanding because of its anatomic location and size. Moreover, the mouse parotid gland contains high concentrations of RNases, making it difficult to isolate high-quality RNA. So far, appropriate methods for optimal perfusion-fixation and dissection of mouse parotid glands, as well as the isolation of high quality RNA from this tissue, are not available. Here we present a simple, optimized, step-by-step surgical method to perfuse and isolate murine parotid glands. We also compared two common RNA extraction methods (RNeasy Mini Kit versus TRIzol) for their yields of high-quality, intact RNA from human and murine parotid gland tissues that were either snap-frozen or immersed in RNAlater stabilization solution. Mouse parotid tissue that was perfused and immersed in RNAlater and human samples immersed in RNAlater exhibited the best RNA quality, independent of the isolation method.

  11. Next-generation sequencing for high-throughput molecular ecology: a step-by-step protocol for targeted multilocus genotyping by pyrosequencing.

    PubMed

    Puritz, Jonathan B; Toonen, Robert J

    2013-01-01

    Next-generation sequencing technology can now provide population biologists and phylogeographers with information at the genomic scale; however, many pertinent questions in population genetics and phylogeography can be answered effectively with modest levels of genomic information. For the past two decades, most population-level studies have lacked nuclear DNA (nDNA) sequence data due to the complications and cost of amplifying and sequencing diploid loci. However, pyrosequencing of emulsion PCR reactions, amplifying from only one molecule at a time, can generate megabases of clonally amplified loci at high coverage, thereby greatly simplifying allelic sequence determination. Here, we present a step-by-step methodology for utilizing the 454 GS FLX Titanium pyrosequencing platform to simultaneously sequence 16 populations (at 20 individuals per population) at 10 different nDNA loci (3,200 loci in total) in one plate of sequencing for less than the cost of traditional Sanger sequencing.

  12. Pulsatile culture of a poly(DL-lactic-co-glycolic acid) sandwiched cell/hydrogel construct fabricated using a step-by-step mold/extraction method.

    PubMed

    Wang, Xiaohong; Sui, Shaochun

    2011-06-01

    To overcome the weak mechanical properties of cell/hydrogel composites, a poly(DL-lactic-co-glycolic acid) sandwiched adipose-derived stem cell (ADSC)/fibrin construct was fabricated using a step-by-step mold/extraction method to generate the middle smooth muscle layer of natural blood vessels. A pulse bioreactor with an adjustable 0-0.2 MPa pressure, 0-7% pulse amplitude, and 0-80 times/min pulse frequency was developed to mimic the liquid movement in the natural blood vessels. This new type of pulse bioreactor is sterilizable and dismantles easily. A comparative study was conducted with static and dynamic in vitro cultures. Exogenous growth factors, such as hepatocyte growth factor, platelet-derived growth factor BB, transforming growth factor β1, and basic fibroblast growth factor were used as additives in the culture medium for inducing the ADSCs into smooth muscle cells. The dynamic training, integrated with the growth factor, induced the transformation of ADSCs into smooth muscle-like cells with regular arrangement. This strategy shows promise of being widely used in tissue engineering and complex organ manufacturing.

  13. Treatment of burns in the first 24 hours: simple and practical guide by answering 10 questions in a step-by-step form

    PubMed Central

    2012-01-01

    Residents in training, medical students and other staff in surgical sector, emergency room (ER) and intensive care unit (ICU) or Burn Unit face a multitude of questions regarding burn care. Treatment of burns is not always straightforward. Furthermore, National and International guidelines differ from one region to another. On one hand, it is important to understand pathophysiology, classification of burns, surgical treatment, and the latest updates in burn science. On the other hand, the clinical situation for treating these cases needs clear guidelines to cover every single aspect during the treatment procedure. Thus, 10 questions have been organised and discussed in a step-by-step form in order to achieve the excellence of education and the optimal treatment of burn injuries in the first 24 hours. These 10 questions will clearly discuss referral criteria to the burn unit, primary and secondary survey, estimation of the total burned surface area (%TBSA) and the degree of burns as well as resuscitation process, routine interventions, laboratory tests, indications of Bronchoscopy and special considerations for Inhalation trauma, immediate consultations and referrals, emergency surgery and admission orders. Understanding and answering the 10 questions will not only cover the management process of Burns during the first 24 hours but also seems to be an interactive clear guide for education purpose. PMID:22583548

  14. Treatment of burns in the first 24 hours: simple and practical guide by answering 10 questions in a step-by-step form.

    PubMed

    Alharbi, Ziyad; Piatkowski, Andrzej; Dembinski, Rolf; Reckort, Sven; Grieb, Gerrit; Kauczok, Jens; Pallua, Norbert

    2012-05-14

    Residents in training, medical students and other staff in surgical sector, emergency room (ER) and intensive care unit (ICU) or Burn Unit face a multitude of questions regarding burn care. Treatment of burns is not always straightforward. Furthermore, National and International guidelines differ from one region to another. On one hand, it is important to understand pathophysiology, classification of burns, surgical treatment, and the latest updates in burn science. On the other hand, the clinical situation for treating these cases needs clear guidelines to cover every single aspect during the treatment procedure. Thus, 10 questions have been organised and discussed in a step-by-step form in order to achieve the excellence of education and the optimal treatment of burn injuries in the first 24 hours. These 10 questions will clearly discuss referral criteria to the burn unit, primary and secondary survey, estimation of the total burned surface area (%TBSA) and the degree of burns as well as resuscitation process, routine interventions, laboratory tests, indications of Bronchoscopy and special considerations for Inhalation trauma, immediate consultations and referrals, emergency surgery and admission orders. Understanding and answering the 10 questions will not only cover the management process of Burns during the first 24 hours but also seems to be an interactive clear guide for education purpose.

  15. Sequential (step-by-step) detection, identification and quantitation of extra virgin olive oil adulteration by chemometric treatment of chromatographic profiles.

    PubMed

    Capote, F Priego; Jiménez, J Ruiz; de Castro, M D Luque

    2007-08-01

    An analytical method for the sequential detection, identification and quantitation of extra virgin olive oil adulteration with four edible vegetable oils--sunflower, corn, peanut and coconut oils--is proposed. The only data required for this method are the results obtained from an analysis of the lipid fraction by gas chromatography-mass spectrometry. A total number of 566 samples (pure oils and samples of adulterated olive oil) were used to develop the chemometric models, which were designed to accomplish, step-by-step, the three aims of the method: to detect whether an olive oil sample is adulterated, to identify the type of adulterant used in the fraud, and to determine how much aldulterant is in the sample. Qualitative analysis was carried out via two chemometric approaches--soft independent modelling of class analogy (SIMCA) and K nearest neighbours (KNN)--both approaches exhibited prediction abilities that were always higher than 91% for adulterant detection and 88% for type of adulterant identification. Quantitative analysis was based on partial least squares regression (PLSR), which yielded R2 values of >0.90 for calibration and validation sets and thus made it possible to determine adulteration with excellent precision according to the Shenk criteria.

  16. Freehand Thoracic Pedicle Screw Placement: Review of Existing Strategies and a Step-by-Step Guide Using Uniform Landmarks for All Levels

    PubMed Central

    Baaj, Ali A

    2016-01-01

    Pedicle screw fixation in the thoracic spine presents certain challenges due to the critical regional neurovascular anatomy as well as the narrow pedicular corridor that typically exists. With increased awareness of the dangers of intraoperative radiation, the ability to place pedicle screws with anatomic landmarks alone is paramount. In this study, we reviewed the literature from 1990 to 2015 for studies that included freehand pedicle screw placement in the thoracic spine with special emphasis on entry points and the trajectories of the screws. We excluded studies that used fluoroscopy guidance, navigation techniques, cadaveric and biomechanical articles, case reports, and experimental studies on animals. The search retrieved 40 articles, and after careful selection, seven articles were analyzed. Over 8,000 screws were placed in the different studies. The mean accuracy for placement of the thoracic screws was 93.3%. However, there is little consensus between studies in entry points, sagittal, and axial trajectories of the screws. We complete this review by presenting our step-by-step technique for the placement of freehand pedicle screws in the thoracic spine. PMID:27014535

  17. Hierarchical Assembly of a {Mn(II)15Mn(III)4} Brucite Disc: Step-by-Step Formation and Ferrimagnetism.

    PubMed

    Deng, Yong-Kai; Su, Hai-Feng; Xu, Jia-Heng; Wang, Wen-Guang; Kurmoo, Mohamedally; Lin, Shui-Chao; Tan, Yuan-Zhi; Jia, Jiong; Sun, Di; Zheng, Lan-Sun

    2016-02-03

    In search of functional molecular materials and the study of their formation mechanism, we report the elucidation of a hierarchical step-by-step formation from monomer (Mn) to heptamer (Mn7) to nonadecamer (Mn19) satisfying the relation 1 + Σn6n, where n is the ring number of the Brucite structure using high-resolution electrospray ionization mass spectrometry (HRESI-MS). Three intermediate clusters, Mn10, Mn12, and Mn14, were identified. Furthermore, the Mn19 disc remains intact when dissolved in acetonitrile with a well-resolved general formula of [Mn19(L)x(OH)y(N3)36-x-y](2+) (x = 18, 17, 16; y = 8, 7, 6; HL = 1-(hydroxymethyl)-3,5-dimethylpyrazole) indicating progressive exchange of N3(-) for OH(-). The high symmetry (R-3) Mn19 crystal structure consists of a well-ordered discotic motif where the peripheral organic ligands form a double calix housing the anions and solvent molecules. From the formula and valence bond sums, the charge state is mixed-valent, [Mn(II)15Mn(III)4]. Its magnetic properties and electrochemistry have been studied. It behaves as a ferrimagnet below 40 K and has a coercive field of 2.7 kOe at 1.8 K, which can be possible by either weak exchange between clusters through the anions and solvents or through dipolar interaction through space as confirmed by the lack of ordering in frozen CH3CN. The moment of nearly 50 NμB suggests Mn(II)-Mn(II) and Mn(III)-Mn(III) are ferromagnetically coupled while Mn(II)-Mn(III) is antiferromagnetic which is likely if the Mn(III) are centrally placed in the cluster. This compound displays the rare occurrence of magnetic ordering from nonconnected high-spin molecules.

  18. Step-by-step surgical technique for mandibular reconstruction with fibular free flap: application of digital technology in virtual surgical planning.

    PubMed

    Succo, G; Berrone, M; Battiston, B; Tos, P; Goia, F; Appendino, P; Crosetti, E

    2015-06-01

    At present, mandibular reconstruction with a fibular free flap is the gold standard for functional and esthetic rehabilitation after oncological surgery. The purpose of this study was to describe the computer-assisted mandibular reconstruction procedure adopting the customized solution Synthes ProPlan CMF. The study reports five consecutive patients with benign or malignant disease requiring mandibular reconstruction using a microvascular fibular free flap, pre-operative virtual planning, construction of cutting guides and customized laser pre-bent titanium plates. The surgical technique is discussed in a step-by-step fashion. The average post-operative hospital stay was 18 ± 3 days. Ischemia time was recorded in all five cases, with an average of 75 ± 8 min. No problems were encountered in any surgical step and there were no major complications. Excellent precision of cutting guides and a good fit of pre-bent plates were found on both the mandible and fibula. There was excellent precision in bone to bone contact and position between mandible and fibula graft. Measurement data from the pre-operative and post-operative CT scans were compared. The average difference (Δ) between programed segment lengths and CT control segment lengths was 0.098 ± 0.077 cm. Microsurgical mandibular reconstruction using a virtual surgical planning yields significantly shorter ischemia times and allows more precise osteotomies. The technology is becoming increasingly recognized for its ability to optimize surgical outcomes and minimize operating time. Considering that the extent of resection can be wider than predicted, this results in safer modeling of the fibula only after frozen sections have demonstrated the radicality of resection.

  19. Challenging 21st Century Students to Take the Step-By-Step Approach to a Scientific Investigation by Incorporating Interactive Multimedia Events with a Real Scientist.

    NASA Astrophysics Data System (ADS)

    Delaney, M. P.; Hoban, S.

    2006-12-01

    Rousing students to go beyond the textbook and apply science inquiry skills is one of the most difficult tasks of today`s teacher. Moreover, finding valuable inquiry-based activities that will interest a student can also be daunting. The NASA Exploring Space Challenges was developed last year to provide middle school teachers with an opportunity to get their students involved in real scientific investigations. The framework of the Challenges is not to just give a teacher an activity and leave it to their own timetables to perform in the classroom, if at all. Rather, teachers are provided with an activity with hands-on training, interactivity for their students with a real scientist and a strict timeline students must adhere to. The Challenges model requires students to emulate the same procedures as a scientist when conducting a research project. Students first design a project, submit a short proposal, receive feedback, then conduct an investigation by collecting real data. Students can then ground-truth their results by researching data that may already exist in similar context. Finally, students present their findings to a panel, just as a real scientist would at a professional conference. The activity is taken one step further by providing students with lessons on basic measurement and data collecting skills through a series of videoconferences. The golden carrot, however, is the incentive of a competition. Students have an opportunity to give their oral presentation to a panel of NASA scientists and educators. This format has been a huge success. For example, we found that students are more productive, often due to the need to impress the scientist during a videoconference. Students and teachers are also forced to use technology often under-utilized during the typical school day. We also found that teachers are given access to additional support during the activity, through the videoconferencing events or outside communication. Most importantly, teachers are

  20. Life Cost Based FMEA Manual: A Step by Step Guide to Carrying Out a Cost-based Failure Modes and Effects Analysis

    SciTech Connect

    Rhee, Seung; Spencer, Cherrill; /Stanford U. /SLAC

    2009-01-23

    difficulty (D) is how well the organization controls the development process. Another definition relates to the detectability of a particular failure in the product when it is in the hands of the customer. The former asks 'What is the chance of catching the problem before we give it to the customer'? The latter asks 'What is the chance of the customer catching the problem before the problem results in a catastrophic failure?' (Palady, 1995) These differing definitions confuse the FMEA users when one tries to determine detection difficulty. Are we trying to measure how easy it is to detect where a failure has occurred or when it has occurred? Or are we trying to measure how easy or difficult it is to prevent failures? Ordinal scale variables are used to rank-order industries such as, hotels, restaurants, and movies (Note that a 4 star hotel is not necessarily twice as good as a 2 star hotel). Ordinal values preserve rank in a group of items, but the distance between the values cannot be measured since a distance function does not exist. Thus, the product or sum of ordinal variables loses its rank since each parameter has different scales. The RPN is a product of 3 independent ordinal variables, it can indicate that some failure types are 'worse' than others, but give no quantitative indication of their relative effects. To resolve the ambiguity of measuring detection difficulty and the irrational logic of multiplying 3 ordinal indices, a new methodology was created to overcome these shortcomings, Life Cost-Based FMEA. Life Cost-Based FMEA measures failure/risk in terms of monetary cost. Cost is a universal parameter that can be easily related to severity by engineers and others. Thus, failure cost can be estimated using the following simplest form: Expected Failure Cost = {sup n}{Sigma}{sub i=1}p{sub i}c{sub i}, p: Probability of a particular failure occurring; c: Monetary cost associated with that particular failure; and n: Total number of failure scenarios. FMEA is most

  1. Dual Positive Regulation of Embryo Implantation by Endocrine and Immune Systems--Step-by-Step Maternal Recognition of the Developing Embryo.

    PubMed

    Fujiwara, Hiroshi; Araki, Yoshihiko; Imakawa, Kazuhiko; Saito, Shigeru; Daikoku, Takiko; Shigeta, Minoru; Kanzaki, Hideharu; Mori, Takahide

    2016-03-01

    In humans, HCG secreted from the implanting embryo stimulates progesterone production of the corpus luteum to maintain embryo implantation. Along with this endocrine system, current evidence suggests that the maternal immune system positively contributes to the embryo implantation. In mice, immune cells that have been sensitized with seminal fluid and then the developing embryo induce endometrial differentiation and promote embryo implantation. After hatching, HCG activates regulatory T and B cells through LH/HCG receptors and then stimulates uterine NK cells and monocytes through sugar chain receptors, to promote and maintain pregnancy. In accordance with the above, the intrauterine administration of HCG-treated PBMC was demonstrated to improve implantation rates in women with repeated implantation failures. These findings suggest that the maternal immune system undergoes functional changes by recognizing the developing embryos in a stepwise manner even from a pre-fertilization stage and facilitates embryo implantation in cooperation with the endocrine system.

  2. Neurons in monkey dorsal raphe nucleus code beginning and progress of step-by-step schedule, reward expectation, and amount of reward outcome in the reward schedule task.

    PubMed

    Inaba, Kiyonori; Mizuhiki, Takashi; Setogawa, Tsuyoshi; Toda, Koji; Richmond, Barry J; Shidara, Munetaka

    2013-02-20

    The dorsal raphe nucleus is the major source of serotonin in the brain. It is connected to brain regions related to reward processing, and the neurons show activity related to predicted reward outcome. Clinical observations also suggest that it is important in maintaining alertness and its apparent role in addiction seems to be related to reward processing. Here, we examined whether the neurons in dorsal raphe carry signals about reward outcome and task progress during multitrial schedules. We recorded from 98 single neurons in dorsal raphe of two monkeys. The monkeys perform one, two, or three visual discrimination trials (schedule), obtaining one, two, or three drops of liquid. In the valid cue condition, the length and brightness of a visual cue indicated schedule progress and reward amount, respectively. In the random cue condition, the visual cue was randomly presented with respect to schedule length and reward amount. We found information encoded about (1) schedule onset, (2) reward expectation, (3) reward outcome, and (4) reward amount in the mean firing rates. Information theoretic analysis showed that the temporal variation of the neuronal responses contained additional information related to the progress of the schedule toward the reward rather than only discriminating schedule onset or reward/no reward. When considered in light of all that is known about the raphe in anatomy, physiology, and behavior, the rich encoding about both task progress and predicted reward outcome makes the raphe a strong candidate for providing signals throughout the brain to coordinate persistent goal-seeking behavior.

  3. Finding the Magic Step by Step.

    ERIC Educational Resources Information Center

    Maidenberg, Claudia

    2000-01-01

    Staff at the Cucamonga (California) School District discovered no magic key to improving mediocre student performance in their schools. Academic gains became evident only after implementing several steady-improvement strategies in teaching, instructional technologies, learning focus, libraries, remedial reading, and summer school. (MLH)

  4. Building Reading Skills Step by Step

    ERIC Educational Resources Information Center

    Lash, Rebecca

    2005-01-01

    FAME is an acronym for a four-course program titled Foundations, Adventures, Mastery, and Explorations. Reading Is FAME is a research-based, developmental reading program for adolescents reading below grade level. The program incorporates a series of four courses designed for students in grades 7-12. The FAME curriculum helps students by…

  5. 50 Literacy Strategies: Step by Step.

    ERIC Educational Resources Information Center

    Tompkins, Gail E.

    Intended as a resource for elementary and middle school teachers for use in literature focus units, reading and writing workshop, or thematic units, this book contains new instructional strategies such as interactive writing, story retelling, and word sorts. The book offers a grid recommending the most appropriate usage for each strategy,…

  6. Golgi-Cox Staining Step by Step

    PubMed Central

    Zaqout, Sami; Kaindl, Angela M.

    2016-01-01

    Golgi staining remains a key method to study neuronal morphology in vivo. Since most protocols delineating modifications of the original staining method lack details on critical steps, establishing this method in a laboratory can be time-consuming and frustrating. Here, we describe the Golgi-Cox staining in such detail that should turn the staining into an easily feasible method for all scientists working in the neuroscience field. PMID:27065817

  7. Lateral Thinking; Creativity Step by Step.

    ERIC Educational Resources Information Center

    de Bono, Edward

    The purpose of thinking is to collect information and to make the best possible use of it. Because of the way the mind works to create fixed concept patterns we cannot make the best use of new information unless we have some means for restructuring the old patterns and bringing them up to date. Our traditional methods of thinking teach us how to…

  8. Some Notes on a Functional Equation. Classroom Notes

    ERIC Educational Resources Information Center

    Ren, Zhong-Pu; Wu, Zhi-Qin; Zhou, Qi-Fa; Guo, Bai-Ni; Qi, Feng

    2004-01-01

    In this short note, a mathematical proposition on a functional equation for f(xy)=xf(y) + yf(x)for x,y [does not equal] 0, which is encountered in calculus, is generalized step by step. These steps involve continuity, differentiability, a functional equation, an ordinary differential linear equation of the first order, and relationships between…

  9. Noted

    ERIC Educational Resources Information Center

    Nunberg, Geoffrey

    2013-01-01

    Considering how much attention people lavish on the technologies of writing--scroll, codex, print, screen--it's striking how little they pay to the technologies for digesting and regurgitating it. One way or another, there's no sector of the modern world that is not saturated with note-taking--the bureaucracy, the liberal professions, the…

  10. Step by Step': A Community Based Rehabilitation Project with Disabled Children in Guyana. Bilingual Version = Pas a pas: Un project de readaptation a base communautaire pour les enfants handicapes en Guyane. Version bilingue. Notes, Comments...No. 189.

    ERIC Educational Resources Information Center

    O'Toole, Brian

    The document, in both English and French, describes a 2-year project in Guyana based on the principle of community-based rehabilitation (CBR), which stresses training local community residents as supervisors to provide training of rehabilitation workers and direct services to children with disabilities living in rural areas. The program provided…

  11. Notes on sedimentation activities calendar year 1977

    USGS Publications Warehouse

    ,

    1979-01-01

    The need for disseminating current information on activities in the field of sedimentation was proposed by the Chairman of the Federal Interagency River Basin Committee's Subcommittee on Sedimentation shortly after the subcommittee was formed in May 1946. At the fifth meeting of the subcommittee on September 17, 1946, the members approved this proposal and agreed to the issuance of a quarterly report as one means of effecting better coordination of the work of various Federal agencies in the field of sedimentation.

  12. Notes on sedimentation activities calendar year 1979

    USGS Publications Warehouse

    ,

    1980-01-01

    This report is a digest of information furnished by Federal Agencies on sedimentation investigations, both ongoing and planned. Included in the report are a review of important findings, new methodologies, new publications, laboratory and other research activities, and other pertinent information. The material is organized on the basis of the 21 water resources regions delineated by the U.S. Water Resources Council (WRC) for use in the national assessment (see figure 1). A listing by WRC region of stations at which sediment data have been obtained is given in table 3 of the appendix. Within each region, the stations are arranged according to their 8-digit hydrologic unit code. Stations for which the hydrologic unit code was not available are given at the end of the listing under "Miscellaneous." Also given in the appendix is an explanation of the column headings in the station listings, the code number and abbreviations used for State, county, and other areas (table 1), and the code for each organization reporting activities in this volume (table 2).

  13. A Monte-Carlo step-by-step simulation code of the non-homogeneous chemistry of the radiolysis of water and aqueous solutions. Part I: theoretical framework and implementation.

    PubMed

    Plante, Ianik

    2011-08-01

    The importance of the radiolysis of water in irradiation of biological systems has motivated considerable theoretical and experimental work in the radiation chemistry of water and aqueous solutions. In particular, Monte-Carlo simulations of radiation track structure and non-homogeneous chemistry have greatly contributed to the understanding of experimental results in radiation chemistry of heavy ions. Actually, most simulations of the non-homogeneous chemistry are done using the Independent Reaction Time (IRT) method, a very fast technique. The main limitation of the IRT method is that the positions of the radiolytic species are not calculated as a function of time, which is needed to simulate the irradiation of more complex systems. Step-by-step (SBS) methods, which are able to provide such information, have been used only sparsely because these are time consuming in terms of calculation. Recent improvements in computer performance now allow the regular use of the SBS method in radiation chemistry. In the present paper, the first of a series of two, the SBS method is reviewed in detail. To these ends, simulation of diffusion of particles and chemical reactions in aqueous solutions is reviewed, and implementation of the program is discussed. Simulation of model systems is then performed to validate the adequacy of stepwise diffusion and reaction schemes. In the second paper, radiochemical yields of simulated radiation tracks calculated by the SBS program in different conditions of LET, pH, and temperature are compared with results from the IRT program and experimental data.

  14. Appropriate Technology for the Classroom--Using "Post-it Notes" as an Active Learning Tool.

    ERIC Educational Resources Information Center

    Weisenberg, Richard C.

    1997-01-01

    Discusses the use of Post-it Notes as effective teaching devices. Presents activities that use Post-it Notes including concept mapping, molecular modeling, group activities illustrating multi-step biological processes, and genetics activities. Highlights the use of the constructivist approach. (JRH)

  15. Note Launchers: Promoting Active Reading of Mathematics Textbooks

    ERIC Educational Resources Information Center

    Helms, Josh W.; Helms, Kimberly Turner

    2010-01-01

    Note launchers, an instructor-designed reading guide, model how to select, decide, and focus upon what textbook material is important to learn. Reading guides are specially-designed study aids that can steer students through difficult parts of assigned readings (Bean, 1996) while encouraging advance preparation. As an example of a reading guide,…

  16. The Best of "Notes Plus": Practical Classroom Activities for Junior and Senior High School Students.

    ERIC Educational Resources Information Center

    Cline, Ruth K. J., Comp.

    This book is a collection of class activities and lesson plans from "NOTES Plus." The book focuses on three special columns from "NOTES Plus": "Classic of the Month,""Literature Assignment of the Month," and "Writing Assignment of the Month," that contain longer and more involved strategies for…

  17. Step by Step to Smoke-Free Schools.

    ERIC Educational Resources Information Center

    VanSciver, James H.; Roberts, H. Earl

    1989-01-01

    This ERIC digest discusses ways of effectively banning smoking in schools so that controversies do not continue after implementation of the policy. By advocating a process approach, the document cites steps taken by the Lake Forest School Board to prohibit smoking in and around school grounds. Step one involved committee planning involving…

  18. Transitional B cells: step by step towards immune competence.

    PubMed

    Chung, James B; Silverman, Michael; Monroe, John G

    2003-06-01

    Transitional B cells mark the crucial link between bone-marrow (BM) immature and peripheral mature B cells. Examination reveals unexpected heterogeneity, consisting of contiguous subsets with phenotypic and functional differences. Data point to the late transitional B-cell stage as a crucial juncture at which developing B cells gain access to splenic follicles, become responsive to T-cell help and lose sensitivity to negative selection, characterizing the immature B-cell response to B-cell antigen receptor (BCR) signaling in vitro and in vivo. The biological and molecular processes directing maturation through this stage are becoming clearer through biochemical studies and murine models deficient in various components of the BCR signaling pathway.

  19. Step by Step: Using Kodaly To Build Vocal Improvisation.

    ERIC Educational Resources Information Center

    Whitcomb, Rachel

    2003-01-01

    Describes how to teach elementary students about vocal improvisation using the Kodaly-based approach. Discusses the three steps involved in this technique: (1) develop familiar singing patterns; (2) use a question and answer format; and (3) begin improvisation. Includes examples of solfege patterns and a vocal question and answer. (CMK)

  20. Topographic ERP analyses: a step-by-step tutorial review.

    PubMed

    Murray, Micah M; Brunet, Denis; Michel, Christoph M

    2008-06-01

    In this tutorial review, we detail both the rationale for as well as the implementation of a set of analyses of surface-recorded event-related potentials (ERPs) that uses the reference-free spatial (i.e. topographic) information available from high-density electrode montages to render statistical information concerning modulations in response strength, latency, and topography both between and within experimental conditions. In these and other ways these topographic analysis methods allow the experimenter to glean additional information and neurophysiologic interpretability beyond what is available from canonical waveform analyses. In this tutorial we present the example of somatosensory evoked potentials (SEPs) in response to stimulation of each hand to illustrate these points. For each step of these analyses, we provide the reader with both a conceptual and mathematical description of how the analysis is carried out, what it yields, and how to interpret its statistical outcome. We show that these topographic analysis methods are intuitive and easy-to-use approaches that can remove much of the guesswork often confronting ERP researchers and also assist in identifying the information contained within high-density ERP datasets.

  1. Tick Removal: A Step-by-Step Guide (For Parents)

    MedlinePlus

    ... do? First, don't panic. It's true that Lyme disease is the most common tick-borne disease in ... United States, but your child's risk of developing Lyme disease after being bitten by a tick is very ...

  2. [The central vein catheterization. 2. Procedure, step by step].

    PubMed

    Schmalz-Ott, Stéphane; Monti, Matteo; Vollenweider, Peter

    2008-10-29

    Several approaches exist for central vein catheterization. Mastery of the various steps of this procedure and understanding of the basics of asepsis are critical to prevent any complication. They also built the basis for an exhaustive communication with the patient, to obtain an informed consent. This article can in addition be used to develop a checklist in order to (self-)assess competence in procedural skills.

  3. Building Rubrics: A Step-By-Step Process

    ERIC Educational Resources Information Center

    Brown, Carol A.

    2008-01-01

    School media specialists hold the key to ensuring successful research projects that bring the world, and its vast amount of information, into a manageable perspective. More than ever, professionals in school libraries have the responsibility of guiding students to become information literate citizens in this new century. An important contribution…

  4. Step by Step: Avoiding Spiritual Bypass in 12-Step Work

    ERIC Educational Resources Information Center

    Cashwell, Craig S.; Clarke, Philip B.; Graves, Elizabeth G.

    2009-01-01

    With spirituality as a cornerstone, 12-step groups serve a vital role in the recovery community. It is important for counselors to be mindful, however, of the potential for clients to be in spiritual bypass, which likely will undermine the recovery process.

  5. Thermodynamics of trajectories of open quantum systems, step by step

    NASA Astrophysics Data System (ADS)

    Pigeon, Simon; Xuereb, André

    2016-06-01

    Thermodynamics of trajectories promises to make possible the thorough analysis of the dynamical properties of an open quantum system, a sought-after goal in modern physics. Unfortunately, calculation of the relevant quantities presents severe challenges. Determining the large-deviation function that gives access to the full counting statistics associated with a dynamical order parameter is challenging, if not impossible, even for systems evolving in a restricted Liouville space. Acting on the realisation that the salient features of most dynamical systems are encoded in the first few moments of the counting statistics, in this article we present a method that gives sequential access to these moments. Our method allows for obtaining analytical result in several cases, as we illustrate, and allows using large deviation theory to reinterpret certain well-known results.

  6. Step by step: Design procedures for stepped chutes

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The 2013 Farm Bill reaffirms the importance of the investment in America's infrastructure and for the economic growth of our rural communities by authorizing $85 million per year and $250 million in Commodity Credit Corporation funding for watershed rehabilitation through 2018. This investment is e...

  7. A Step-by-Step Guide to Response to Intervention

    ERIC Educational Resources Information Center

    Butler, Lorrie

    2009-01-01

    The summer before the 2003-2004 year, the author was contacted by a district director of exceptional student education (ESE) about participating in a new program. She described it as a problem-solving method that would help them identify and provide interventions for K-2 students who were not making adequate progress in reading. The district would…

  8. A Step-by-Step Study of Formative Assessment

    ERIC Educational Resources Information Center

    Pietsch, Laura

    2013-01-01

    This article presents a guide to the development of formative assessments for school librarians participating in professional learning communities (PLC). It describes librarians' reading of assigned books, meeting with their PLCs, and incorporation of learned strategies in their daily instruction. Central library service readers' regular visits to…

  9. Lesson Organization: Big Vision Step-by-Step Execution

    ERIC Educational Resources Information Center

    Notar, Charles E.; Barkley, Jordan M.

    2009-01-01

    The National Board for Professional Teaching Standards (NBPTS) proposition 3 states "teachers are responsible for managing and monitoring student learning." They know how "...to organize instruction to meet instructional goals." This article provides 14 organizational patterns for use in organizing instruction in any of the content areas. The 14…

  10. Experimental Summary: Step-by-Step Towards New Physics

    NASA Astrophysics Data System (ADS)

    Schwartz, A. J.

    2016-11-01

    We summarize some highlights from experimental results presented at the XIIth International Conference on Beauty, Charm, and Hyperons in Hadronic Interactions, held at George Mason University June 12-18, 2016.

  11. A Step-by-Step Guide to Personalize Learning

    ERIC Educational Resources Information Center

    Bray, Barbara; McClaskey, Kathleen

    2013-01-01

    It is known that every learner is unique and that one-size-fits-all instruction does not work for most. How can a classroom environment be created that gives each learner voice and choice? The co-founders of Personalize Learning, LLC, offer a detailed six-step approach. This article provides the background on what is and what is not Personalized…

  12. A Step by Step Protocol for Subretinal Surgery in Rabbits

    PubMed Central

    Al-Nawaiseh, Sami; Thieltges, Fabian; Liu, Zengping; Strack, Claudine; Brinken, Ralf; Braun, Norbert; Wolschendorf, Marc; Maminishkis, Arvydas; Eter, Nicole; Stanzel, Boris V.

    2016-01-01

    Age related macular degeneration (AMD), retinitis pigmentosa, and other RPE related diseases are the most common causes for irreversible loss of vision in adults in industrially developed countries. RPE transplantation appears to be a promising therapy, as it may replace dysfunctional RPE, restore its function, and thereby vision. Here we describe a method for transplanting a cultured RPE monolayer on a scaffold into the subretinal space (SRS) of rabbits. After vitrectomy xenotransplants were delivered into the SRS using a custom made shooter consisting of a 20-gauge metallic nozzle with a polytetrafluoroethylene (PTFE) coated plunger. The current technique evolved in over 150 rabbit surgeries over 6 years. Post-operative follow-up can be obtained using non-invasive and repetitive in vivo imaging such as spectral domain optical coherence tomography (SD-OCT) followed by perfusion-fixed histology. The method has well-defined steps for easy learning and high success rate. Rabbits are considered a large eye animal model useful in preclinical studies for clinical translation. In this context rabbits are a cost-efficient and perhaps convenient alternative to other large eye animal models. PMID:27684952

  13. Tick Removal: A Step-by-Step Guide (For Parents)

    MedlinePlus

    ... Evaluate Your Child's Lyme Disease Risk Lyme Disease Rocky Mountain Spotted Fever Lyme Disease Hey! A Tick Bit Me! Bug Bites and Stings What's My Lyme Disease Risk? Rocky Mountain Spotted Fever Lyme Disease Contact Us Print Resources Send to ...

  14. A Step by Step Protocol for Subretinal Surgery in Rabbits.

    PubMed

    Al-Nawaiseh, Sami; Thieltges, Fabian; Liu, Zengping; Strack, Claudine; Brinken, Ralf; Braun, Norbert; Wolschendorf, Marc; Maminishkis, Arvydas; Eter, Nicole; Stanzel, Boris V

    2016-09-13

    Age related macular degeneration (AMD), retinitis pigmentosa, and other RPE related diseases are the most common causes for irreversible loss of vision in adults in industrially developed countries. RPE transplantation appears to be a promising therapy, as it may replace dysfunctional RPE, restore its function, and thereby vision. Here we describe a method for transplanting a cultured RPE monolayer on a scaffold into the subretinal space (SRS) of rabbits. After vitrectomy xenotransplants were delivered into the SRS using a custom made shooter consisting of a 20-gauge metallic nozzle with a polytetrafluoroethylene (PTFE) coated plunger. The current technique evolved in over 150 rabbit surgeries over 6 years. Post-operative follow-up can be obtained using non-invasive and repetitive in vivo imaging such as spectral domain optical coherence tomography (SD-OCT) followed by perfusion-fixed histology. The method has well-defined steps for easy learning and high success rate. Rabbits are considered a large eye animal model useful in preclinical studies for clinical translation. In this context rabbits are a cost-efficient and perhaps convenient alternative to other large eye animal models.

  15. Astronaut Frank Culbertson takes notes about mission activity on flight deck

    NASA Technical Reports Server (NTRS)

    1993-01-01

    On Discovery's aft flight deck, Astronaut Frank L. Culbertson Jr., mission commander, takes notes about mission activity. Culbertson is wearing sun glasses to block sun glare from the overhead window.

  16. Research in subliminal psychodynamic activation: note on Masling (1998).

    PubMed

    Fudin, R

    1999-04-01

    Masling (1998) questioned Malik, Apel, Nelham, Rutkowski, and Ladd's 1997 suggestion that subliminal psychodynamic activation research with MOMMY AND I ARE ONE should be restricted. Problems in Masling's paper and the scope of research with MOMMY AND I ARE ONE are discussed. His position that such research should not be restricted is supported on the condition that subliminal psychodynamic activation research with MOMMY AND I ARE ONE (and other messages) use Fudin's 1986 procedure that could clarify the interpretation of successful experimental outcomes.

  17. NADPH OXIDASE: STRUCTURE AND ACTIVATION MECHANISMS (REVIEW). NOTE I.

    PubMed

    Filip-Ciubotaru, Florina; Manciuc, Carmen; Stoleriu, Gabriela; Foia, Liliana

    2016-01-01

    NADPH oxidase (nicotinamide adenine dinucleotide phosphate-oxidase), with its generically termed NOX isoforms, is the major source of ROS (reactive oxigen species) in biological systems. ROS are small oxygen-derived molecules with an important role in various biological processes (physiological or pathological). If under physiological conditions some processes are beneficial and necessary for life, under pathophysiological conditions they are noxious, harmful. NADPH oxidases are present in phagocytes and in a wide variety of nonphagocytic cells. The enzyme generates superoxide by transferring electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen to produce superoxide anion, a reactive free-radical. Structurally, NADPH oxidase is a multicomponent enzyme which includes two integral membrane proteins, glycoprotein gp9 1 Phox and adaptor protein p22(phox), which together form the heterodimeric flavocytochrome b558 that constitutes the core of the enzyme. During the resting state, the multidomain regulatory subunits p40P(phox), p47(phox), p67(Phox) are located in the cytosol organized as a complex. The activation of phagocytic NADPH oxidase occurs through a complex series of protein interactions.

  18. 2012 Workplace and Gender Relations Survey of Active Duty Members. Survey Note and Briefing

    DTIC Science & Technology

    2013-03-15

    Exercises /Alerts Percent of Active Duty Members Who Experienced Unwanted Sexual Contact, by Gender WGRA 2012 Q35 Margins of error range from ±4% to ±12...harassment in the active duty force. This survey note and accompanying briefing (Appendix) provide information on the prevalence rates of sexual ...ELATIONS SURVEYSH R 2012 Workplace and Gender Relations Survey of Active Duty Members 2 Unwanted Sexual Contact 2006 2010 2012 Women: 6.8% Men

  19. Step-by-step thermal transformations of a new porous coordination polymer [(H{sub 2}O){sub 5}CuBa(Me{sub 2}mal){sub 2}]{sub n} (Me{sub 2}mal{sup 2-}=dimethylmalonate): Thermal degradation to barium cuprate

    SciTech Connect

    Zauzolkova, Natalya; Dobrokhotova, Zhanna; Lermontov, Anatoly; Zorina, Ekaterina; Emelina, Anna; Bukov, Mikhail; Sidorov, Aleksey; Kiskin, Mikhail; Bogomyakov, Artem; Lytvynenko, Anton; Kolotilov, Sergey; Velikodnyi, Yuriy; Kovba, Maksim

    2013-01-15

    The reactions of CuSO{sub 4}{center_dot}5H{sub 2}O, dimethylmalonic acid and Ba(OH){sub 2}{center_dot}H{sub 2}O (Cu: H{sub 2}Me{sub 2}mal: Ba=1: 2: 2) in aqueous and aqueous-ethanol solutions (H{sub 2}O: EtOH=1: 1) resulted in formation of 3D-porous coordination polymers [(H{sub 2}O){sub 3}({mu}-H{sub 2}O){sub 2}CuBa({mu}{sub 3}-Me{sub 2}mal)(Me{sub 2}mal)]{sub n} (1) and [({mu}-H{sub 2}O)CuBa({mu}{sub 3}-Me{sub 2}mal)({mu}{sub 4}-Me{sub 2}mal)]{sub n} (2), respectively. It has been shown that compound 2 was an intermediate in the thermal degradation of compound 1. Thorough studies of solid-state thermolysis of 1 and 2 allowed to detect formation of coordination polymer [CuBa({mu}{sub 4}-Me{sub 2}mal)({mu}{sub 5}-Me{sub 2}mal)]{sub n} (3), structure of which was determined by X-ray powder diffraction. It has been found that the channels in polymer 3 were accessible for guest molecules (MeOH). Theoretical estimation of methanol diffusion barrier was carried out. Complete solid-phase thermolysis of 1 and 2 leads to a mixture of BaCuO{sub 2}, BaCO{sub 3}, and CuO. Special conditions for obtaining of a crystalline phase of pure cubic BaCuO{sub 2} were determined. - Graphical abstract: Step-by-step transformation of new coordination polymer [(H{sub 2}O){sub 5}CuBa(Me{sub 2}mal){sub 2}]{sub n} to [(H{sub 2}O)CuBa(Me{sub 2}mal){sub 2}]{sub n} and [CuBa(Me{sub 2}mal){sub 2}]{sub n} were performed. Dehydration of initial compound leads to structural changes of 12-membered ring fragment. All compounds have porous structure. The final product of thermal decomposition is crystalline phase of individual cubic BaCuO{sub 2}. Highlights: Black-Right-Pointing-Pointer New 3D-polymers [(H{sub 2}O){sub 5}CuBa(Me{sub 2}mal){sub 2}]{sub n} and [(H{sub 2}O)CuBa(Me{sub 2}mal){sub 2}]{sub n} were synthesized. Black-Right-Pointing-Pointer Thermal analysis showed step-by-step transformations of [(H{sub 2}O){sub 5}CuBa(Me{sub 2}mal){sub 2}]{sub n}. Black-Right-Pointing-Pointer Crystalline

  20. A Monte-Carlo step-by-step simulation code of the non-homogeneous chemistry of the radiolysis of water and aqueous solutions--Part II: calculation of radiolytic yields under different conditions of LET, pH, and temperature.

    PubMed

    Plante, Ianik

    2011-08-01

    The importance of the radiolysis of water in the initial events following irradiation of biological systems has motivated considerable theoretical and experimental work in the field of radiation chemistry of water and aqueous systems. These studies include Monte-Carlo simulations of the radiation track structure and of the non-homogeneous chemical stage, which have been successfully used to calculate the yields of radiolytic species (H(·), (·)OH, H(2), H(2)O(2), e (aq) (-) , …). Most techniques used for the simulation of the non-homogeneous chemical stage such as the independent reaction time (IRT) technique and diffusion kinetics methods do not calculate the time evolution of the positions of the radiolytic species. This is a major limitation to their extension to the simulation of the irradiation of radiobiological systems. Step-by-step (SBS) simulation programs provide such information, but they are very demanding in term of computer power and storage capacity. Recent improvements in computer performance now allow the regular use of the SBS method in radiation chemistry simulations. In the first of a series of two papers, the SBS method has been reviewed in details and the implementation of a SBS code has been discussed. In this second paper, the results of several studies are presented: (1) the time evolution of the radiolytic yields from the formation of the radiation track to 10(-6) s; (2) the effect of pH on yields (pH ~ 0.4-7.0); (3) the effect of proton energy (and LET) on yields (300 MeV-0.1 MeV), and iv) the effect of the ion type ((1)H(+), (4)He(2+), (12)C(6+)) on yields. Nonbiological applications, i.e., the study of the temperature on the yields (about 25-300°C) and the simulation of the time evolution of G(Fe(3+)) in the Fricke dosimeter are also discussed.

  1. Summary of solar activity observed at the Mauna Loa Solar Observatory: 1980-1983. Technical note

    SciTech Connect

    Rock, K.; Fisher, R.; Garcia, C.; Yasukawa, E.

    1983-11-01

    The following technical note summarizes solar activity observed during the first four years operation of the experiment systems of the Coronal Dynamics Project, which are located at the Mauna Loa Solar Observatory. This short report has been produced with the general aim of providing users of Mauna Loa observations with a summary of data for specific events. So that this table might be as useful as possible, a comprehensive review of three sources was performed. The plain language logs, identified as the so-called observer's logs, the now-discontinued activity logs, and the prominence monitor quality control logs were the sources from which the information in the following tables was obtained. It is expected that this review will be of particular use to those investigators who intend to use both the K-coronameter data base and the SMM Coronagraph-Polarimeter data for the study of coronal transient events.

  2. Editor's note

    NASA Astrophysics Data System (ADS)

    Umapathy, Siva

    2017-01-01

    This is an editor's note related to the publication 'Biologically active and thermally stable polymeric Schiff base and its metal polychelates: Their synthesis and spectral aspects' by Raza Rasool and Sumaiya Hasnain, which appeared in Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 148 (2015) 435-443.

  3. Notes on Linguistics, 1996.

    ERIC Educational Resources Information Center

    Payne, David, Ed.

    1996-01-01

    The four 1996 issues of this journal contain the following articles: "Sketch of Autosegmental Tonology" (H. Andrew Black); "System Relationships in Assessing Dialect Intelligibility" (Margaret Milliken, Stuart Milliken); "A Step-by-Step Introduction to Government and Binding Theory of Syntax" (Cheryl A. Black);…

  4. Apparatus Notes.

    ERIC Educational Resources Information Center

    Eaton, Bruce G., Ed.

    1980-01-01

    Presents four notes that report new equipment and techniques of interest to physics teachers. These notes deal with collosions of atoms in solids, determining the viscosity of a liquid, measuring the speed of sound and demonstrating Doppler effect. (HM)

  5. Suicide notes.

    PubMed

    O'Donnell, I; Farmer, R; Catalan, J

    1993-07-01

    Detailed case reports of incidents of suicide and attempted suicide on the London Underground railway system between 1985 and 1989 were examined for the presence of suicide notes. The incidence of note-leaving was 15%. Notes provided little insight into the causes of suicide as subjectively perceived, or strategies for suicide prevention.

  6. Chemistry Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1980

    1980-01-01

    Presents 12 chemistry notes for British secondary school teachers. Some of these notes are: (1) a simple device for testing pH-meters; (2) portable fume cupboard safety screen; and (3) Mass spectroscopy-analysis of a mass peak. (HM)

  7. Gifted and Talented Students: A Step by Step Approach to Programming.

    ERIC Educational Resources Information Center

    Clasen, Robert E.; Clasen, Donna Rae

    In response to the estimate that 15-20 percent of the school-age population in Wisconsin can be classified as gifted and talented, this document suggests approaches educators can take to identify these students and to design programs to meet their special needs. An introductory section offers an overview of gifted and talented programming options…

  8. Break-Up of Oil on Rough Seas - Simplified Models and Step-by-Step Calculations

    DTIC Science & Technology

    1982-03-01

    in the inertial subrange, the splitting and resisting forces will balance and the splitting process will cease. The smallest droplet size in that case...and the drag force resisting the movement. The drag force acting on a droplet is a function of the Reynolds number of the droplet. For Reynolds numbers...1190 FI 4.= D 1 1200 FOR I-1= TO N 1210 IF I< NIF2 .L0 GOTO 124.0 1220 GOSU 2610 1.230

  9. Teaching the Use of a Long Cane Step by Step: Suggestions for Progressive, Methodical Instruction

    ERIC Educational Resources Information Center

    Sauerburger, Dona; Bourquin, Eugene

    2010-01-01

    A fundamental part of the orientation and mobility curriculum is the acquisition and retention of skills in using a long cane automatically and proficiently to detect and negotiate obstacles and drop-offs. Using practitioners' experiences and the principles of learning theory, instructors can monitor students' advancement and adapt teaching…

  10. Beginning Interpretative Inquiry: A Step-by-Step Approach to Research and Evaluation

    ERIC Educational Resources Information Center

    Morehouse, Richard

    2011-01-01

    "Beginning Interpretive Inquiry" importantly makes the distinction between the use of "inquiry" rather than interpretive research or interpretive evaluation. Richard Morehouse explores how inquiry is a far more inclusive concept that allows for a detailed understanding of both research and evaluation. The author draws on his personal experiences…

  11. A step-by-step guide to home telehealth program planning.

    PubMed

    Kinsella, Audrey

    2003-08-01

    Many home health providers have become familiar with the idea of home telehealth service, but planning its optimal delivery nevertheless presents a challenge. This article presents the first steps agencies need to take before the "televisiting" can begin.

  12. Educating the Educator: A Step-by-Step Process for Referring Children for Early Intervention Services

    ERIC Educational Resources Information Center

    Gibson, Craig; Jones, Sandra; Patrick, Tamika

    2010-01-01

    Classroom management, child safety, curriculum and program requirements, portfolio assessment, and time management are just a few of the many obstacles an educator must overcome on a day-to-day basis. Although they may be on an entirely different level, students may be facing their own unique challenges. Educators, as professionals, have the…

  13. Blending Together, Step by Step: Principal Uses Professional Learning to Combine Two School Cultures into One

    ERIC Educational Resources Information Center

    Martin, Linda E.; Shafer, Tracy; Kragler, Sherry

    2009-01-01

    There is no denying that combining two schools, or even opening a new school, is loaded with challenges and frustrations as well as high expectations. Principal Tracy Shafer saw a rural school consolidation as an opportunity to use professional development to create a community focused on student learning, meeting the need for high-quality…

  14. Extracorporeal gas exchange in acute lung injury: step by step towards expanded indications?

    PubMed Central

    2010-01-01

    Extracorporeal membrane oxygenation (ECMO) is widely accepted as a rescue therapy in patients with acute life-threatening hypoxemia in the course of severe acute respiratory distress syndrome (ARDS). However, possible side effects and complications are considered to limit beneficial outcome effects. Therefore, widening indications with the aim of reducing ventilator induced lung injury (VILI) is still controversial. Consequently, technological progress is an important strategy. Miniaturized ECMO systems are believed to simplify handling and reduce side effects and complications. Mueller and co-workers evaluated such a small-sized device in 60 patients with severe ARDS. They accomplished both the treatment of severe hypoxemia and reduction of VILI, demonstrating feasibility, a moderate rate of severe complications, and a 45% intensive care survival rate. Although neither randomized nor controlled, this study should encourage others to implement such systems in clinical practice. From a strategic perspective, this is another small but useful step towards implementing extracorporeal gas exchange for the prevention of VILI. It is already common sense that the prevention of acute life-threatening hypoxemia usually outweighs the risks of this technique. The next step should be to prove that prevention of life-threatening VILI balances the risks too. PMID:20236482

  15. Extracorporeal gas exchange in acute lung injury: step by step towards expanded indications?

    PubMed

    Dembinski, Rolf; Kuhlen, Ralf

    2010-01-01

    Extracorporeal membrane oxygenation (ECMO) is widely accepted as a rescue therapy in patients with acute life-threatening hypoxemia in the course of severe acute respiratory distress syndrome (ARDS). However, possible side effects and complications are considered to limit beneficial outcome effects. Therefore, widening indications with the aim of reducing ventilator induced lung injury (VILI) is still controversial. Consequently, technological progress is an important strategy. Miniaturized ECMO systems are believed to simplify handling and reduce side effects and complications. Mueller and co-workers evaluated such a small-sized device in 60 patients with severe ARDS. They accomplished both the treatment of severe hypoxemia and reduction of VILI, demonstrating feasibility, a moderate rate of severe complications, and a 45% intensive care survival rate. Although neither randomized nor controlled, this study should encourage others to implement such systems in clinical practice. From a strategic perspective, this is another small but useful step towards implementing extracorporeal gas exchange for the prevention of VILI. It is already common sense that the prevention of acute life-threatening hypoxemia usually outweighs the risks of this technique. The next step should be to prove that prevention of life-threatening VILI balances the risks too.

  16. Step by Step Assembly of Polynuclear Lanthanide Complexes with a Phosphonated Bipyridine Ligand.

    PubMed

    Souri, Nabila; Tian, Pingping; Lecointre, Alexandre; Lemaire, Zoé; Chafaa, Salah; Strub, Jean-Marc; Cianférani, Sarah; Elhabiri, Mourad; Platas-Iglesias, Carlos; Charbonnière, Loïc J

    2016-12-19

    The synthesis of the octadentate ligand L (LH8 = ((([2,2'-bipyridine]-6,6'-diylbis(methylene))bis(azanetriyl))tetrakis(methylene))tetrakis(phosphonic acid)) is reported. The coordination of L with various lanthanide cations was monitored by absorption and luminescence spectrophotometric titration experiments (Ln = Tb, Yb), potentiometry (Ln = La, Eu, Lu), and mass spectrometry (Ln = Tb). It was found that L forms very stable mononuclear (LnL) species in aqueous solutions (log K = 19.80(5), 19.5(2), and 19.56(5) for La, Eu, and Lu, respectively) with no particular trend along the series. Spectroscopic data showed the Ln cations to be enclosed in the cavity formed by the octadentate ligand, thereby shielding the metal from interactions with water molecules in the first coordination sphere. When more than one equivalent of cations is added, the formation of polynuclear [(LnL)2Lnx] complexes (x = 1-3) can be observed, the presence of which could be confirmed by electrospray and MALDI mass spectrometry experiments. DFT modeling of the mononuclear (LnL) complexes indicated that the coordination of the cation in the cavity of the ligand results in a very asymmetric charge distribution, with a region of small negative electrostatic potential on the hemisphere composed of the chromophoric bipyridyl moiety and an electron-rich domain at the opposite hemisphere around the four phosphonate functions. DFT further showed that this polarization is most likely at the origin of the strong interactions between the (LnL) complexes and the incoming additional cations, leading to the formation of the polynuclear species. (1)H and (31)P NMR were used to probe the possible exchange of the lanthanide complexed in the cavity of the ligand in D2O, revealing no detectable exchange after 4 weeks at 80 °C and neutral pD, therefore pointing out an excellent kinetic inertness.

  17. A Virtual Environment for Process Management. A Step by Step Implementation

    ERIC Educational Resources Information Center

    Mayer, Sergio Valenzuela

    2003-01-01

    In this paper it is presented a virtual organizational environment, conceived with the integration of three computer programs: a manufacturing simulation package, an automation of businesses processes (workflows), and business intelligence (Balanced Scorecard) software. It was created as a supporting tool for teaching IE, its purpose is to give…

  18. Step by Step: Biology Undergraduates' Problem-Solving Procedures during Multiple-Choice Assessment.

    PubMed

    Prevost, Luanna B; Lemons, Paula P

    2016-01-01

    This study uses the theoretical framework of domain-specific problem solving to explore the procedures students use to solve multiple-choice problems about biology concepts. We designed several multiple-choice problems and administered them on four exams. We trained students to produce written descriptions of how they solved the problem, and this allowed us to systematically investigate their problem-solving procedures. We identified a range of procedures and organized them as domain general, domain specific, or hybrid. We also identified domain-general and domain-specific errors made by students during problem solving. We found that students use domain-general and hybrid procedures more frequently when solving lower-order problems than higher-order problems, while they use domain-specific procedures more frequently when solving higher-order problems. Additionally, the more domain-specific procedures students used, the higher the likelihood that they would answer the problem correctly, up to five procedures. However, if students used just one domain-general procedure, they were as likely to answer the problem correctly as if they had used two to five domain-general procedures. Our findings provide a categorization scheme and framework for additional research on biology problem solving and suggest several important implications for researchers and instructors.

  19. Using TRAILS to Assess Student Learning: A Step-by-Step Guide

    ERIC Educational Resources Information Center

    Owen, Patricia L.

    2010-01-01

    School librarians nationwide seek to produce evidence of the library's impact on student learning and achievement. While classroom teachers demonstrate their impact through the use of standardized test scores including end-of-grade tests and SAT/ACT tests, school librarians have long used informal or in-class assessments to gauge student learning.…

  20. Creating a Healthier Life: A Step-By-Step Guide to Wellness

    MedlinePlus

    ... play in the lives of others—like being students, friends, parents, spouses, coworkers, congregants, hobbyists, community members, ... write your thoughts in a journal, listen to music, or talk to family or friends when you ...

  1. Structured English Immersion: A Step-by-Step Guide for K-6 Teachers and Administrators.

    ERIC Educational Resources Information Center

    Haver, Johanna J.

    This book describes Structured English Immersion (SEI) for English language learners (ELLs). Seven chapters focus on the following: (1) "Identification, Assessment, and Placement" (e.g., California's school districts implement SEI and proper placement of students); (2) "Listening Skills" (e.g., time on task, total physical…

  2. Step-by-Step: A Model for Practice-Based Learning

    ERIC Educational Resources Information Center

    Kane, Gabrielle M.

    2007-01-01

    Introduction: Innovative technology has led to high-precision radiation therapy that has dramatically altered the practice of radiation oncology. This qualitative study explored the implementation of this innovation into practice from the perspective of the practitioners in a large academic radiation medicine program and aimed to improve…

  3. A Step-by-Step Design Methodology for a Base Case Vanadium Redox-Flow Battery

    ERIC Educational Resources Information Center

    Moore, Mark; Counce, Robert M.; Watson, Jack S.; Zawodzinski, Thomas A.; Kamath, Haresh

    2012-01-01

    The purpose of this work is to develop an evolutionary procedure to be used by Chemical Engineering students for the base-case design of a Vanadium Redox-Flow Battery. The design methodology is based on the work of Douglas (1985) and provides a profitability analysis at each decision level so that more profitable alternatives and directions can be…

  4. Teen Spaces: The Step-by-Step Library Makeover, Second Edition

    ERIC Educational Resources Information Center

    Bolan, Kimberly

    2008-01-01

    When writing the first edition of "Teen Spaces" in 2002, YA expert Bolan was challenged to find excellent examples. Now, teen spaces abound and interest continues to grow. With a strategic use of web-based technologies--from the author's website to a Flickr account--this new edition showcases success stories as it reaches out to attract a global…

  5. A Step-by-Step Guide to Publishing Journal Articles and Strategies for Securing Impactful Publications

    ERIC Educational Resources Information Center

    Onwuegbuzie, Anthony J.

    2016-01-01

    In the last few years, I have been presenting workshops on publishing (among other topics) in many countries across 6 continents. And presenting these workshops in various countries has allowed me to learn the policies and practices of editors of journals representing numerous countries, thereby helping me to broaden the framework for writing…

  6. A Step-by-Step Guide to Writing a Good History Day Paper.

    ERIC Educational Resources Information Center

    Kohl, Martha

    1992-01-01

    Presents an instructive outline for writing a research paper for National History Day. Organizes the process into three steps: (1) select an interesting topic; (2) develop a strong thesis; and (3) write a well-constructed paper. Includes hints on organization, technical matters, editing, and readability. (DK)

  7. Understanding, Developing, and Writing Effective IEPs: A Step-by-Step Guide for Educators

    ERIC Educational Resources Information Center

    Pierangelo, Roger; Giuliani, George A.

    2007-01-01

    Creating and evaluating Individualized Education Programs (IEPs) for students with disabilities is a major responsibility for teachers and school leaders, yet the process involves legal components not always understood by educators. In "Understanding, Developing, and Writing Effective IEPs," legal and special education experts Roger…

  8. A Step by Step Guide to Outcomes Assessment in the Connecticut Community Colleges.

    ERIC Educational Resources Information Center

    Quinebaug Valley Community Coll., Danielson, CT.

    The report discusses outcomes assessment plans for Connecticut community colleges. It presents a variety of tools for use in assessing course, program, and general education goals. Demonstrations of competence, measures of quality, and justifications of costs have become essential components of institutional effectiveness. A good assessment plan…

  9. Step by Step: Creating a Community-Based Transition Program for Students with Intellectual Disabilities

    ERIC Educational Resources Information Center

    Hartman, Melissa A.

    2009-01-01

    Many students with intellectual disabilities want to graduate with their peers and move on to the next phase of their lives. By the time students have reached age 18, most have exhausted the coursework the school system has to offer, and they have yet to master the skills necessary for employment and independent living. Community-based transition…

  10. An Inquiry-Based Approach of Traditional "Step-by-Step" Experiments

    ERIC Educational Resources Information Center

    Szalay, L.; Tóth, Z.

    2016-01-01

    This is the start of a road map for the effective introduction of inquiry-based learning in chemistry. Advantages of inquiry-based approaches to the development of scientific literacy are widely discussed in the literature. However, unless chemistry educators take account of teachers' reservations and identified disadvantages such approaches will…

  11. Step by Step: Biology Undergraduates’ Problem-Solving Procedures during Multiple-Choice Assessment

    PubMed Central

    Prevost, Luanna B.; Lemons, Paula P.

    2016-01-01

    This study uses the theoretical framework of domain-specific problem solving to explore the procedures students use to solve multiple-choice problems about biology concepts. We designed several multiple-choice problems and administered them on four exams. We trained students to produce written descriptions of how they solved the problem, and this allowed us to systematically investigate their problem-solving procedures. We identified a range of procedures and organized them as domain general, domain specific, or hybrid. We also identified domain-general and domain-specific errors made by students during problem solving. We found that students use domain-general and hybrid procedures more frequently when solving lower-order problems than higher-order problems, while they use domain-specific procedures more frequently when solving higher-order problems. Additionally, the more domain-specific procedures students used, the higher the likelihood that they would answer the problem correctly, up to five procedures. However, if students used just one domain-general procedure, they were as likely to answer the problem correctly as if they had used two to five domain-general procedures. Our findings provide a categorization scheme and framework for additional research on biology problem solving and suggest several important implications for researchers and instructors. PMID:27909021

  12. Climbing the ladder: a step by step approach to international guidelines for water recycling.

    PubMed

    Anderson, J; Adin, A; Crook, J; Davis, C; Hultquist, R; Jimenez-Cisneros, B; Kennedy, W; Sheikh, B; van der Merwe, B

    2001-01-01

    Given the pressures on the world's freshwater resources, recycled water is a valuable resource. Recycled water can increase the reliability of water supply because it is an independent source of water. Water recycling requires effective measures to protect public health and the environment. In the absence of comprehensive international guidelines, different countries have developed different approaches to managing water recycling depending on the understanding of the health risks, their individual economic circumstances, and affordability. Approaches vary between high technology/high cost/low risk and low technology/low cost/controlled risk. Furthermore, differences occur between countries and within individual countries. Inconsistencies can often be traced to lack of a unified scientific position on health effects. These inconsistencies increase public concerns about health risks and may give rise to conservative controls on responses to water recycling projects that some countries may be unable to afford. In this paper, an international panel of authors discusses how the different water recycling approaches might be linked together into international water recycling guidelines. These guidelines would incorporate a uniform approach to assessing hazards and risks while providing flexibility for individual countries to vary requirements to suit local circumstances of affordability and risk. The authors propose a framework of guidelines in which individual countries can progressively improve recycled water quality as lower risk levels become more affordable. The authors argue that a uniform international approach will result in a number of benefits including a better focus on risk management, better targeted research and development efforts and greater public confidence in water recycling. The authors invite discussion on the concepts put forward in the paper.

  13. A Step-by-Step Guide to Propensity Score Matching in R

    ERIC Educational Resources Information Center

    Randolph, Justus J.; Falbe, Kristina; Manuel, Austin Kureethara; Balloun, Joseph L.

    2014-01-01

    Propensity score matching is a statistical technique in which a treatment case is matched with one or more control cases based on each case's propensity score. This matching can help strengthen causal arguments in quasi-experimental and observational studies by reducing selection bias. In this article we concentrate on how to conduct propensity…

  14. Developing a Successful Coaching Philosophy: A Step-by-Step Approach

    ERIC Educational Resources Information Center

    Van Mullem, Pete; Brunner, Dave

    2013-01-01

    The coaching profession demands a high level of accountability and responsibility for the coach. Challenged to achieve success on the scoreboard and promote the positive personal growth of the athlete, a coach seeks guidance from their coaching philosophy. A coaching philosophy is built on a set of standards by which a coach influences, teaches,…

  15. Gestalt and Other Strategies for Exploring Dreams through a Step-by-Step Approach.

    ERIC Educational Resources Information Center

    France, M. Honore; Allen, G. Edward

    1993-01-01

    The Gestalt dream approach is a practical way to explore personal issues. This article demonstrates how dream work can be adapted by counselors to focus clients to direct forms of personal exploration. A four-step strategy is described. (Authors)

  16. Addressing risk in the design of new healthcare services: a step-by-step methodology.

    PubMed

    Remus, Beth

    2008-01-01

    New service design can be done effectively through enterprise risk management (ERM) by identifying the clinical and administrative risks within the new service design. This article proposes a 10-step process describing the business team's tasks and integrating risk management, quality management and patient safety concepts.

  17. Production of soybean phosphatidylcholine-chitosan nanovesicles by reverse phase evaporation: a step by step study.

    PubMed

    Mertins, Omar; Sebben, Marcelo; Pohlmann, Adriana Raffin; da Silveira, Nádya Pesce

    2005-12-01

    In the present work, we describe the preparation of composite nanovesicles containing soybean phosphatidylcholine and polysaccharide chitosan by the reverse phase evaporation method. Nanovesicles free from chitosan prepared in the same way were studied as reference. The production method involves the preparation of reverse micelles followed by the formation of an organogel, which is dispersed in water to yield the final liposomal structures. Structural changes in each step of the nanovesicles preparation were studied by means of static and dynamic light scattering as well as small angle X-ray scattering. Chitosan was also fully characterized in solution. The hydrodynamic radius of the composite nanovesicles is in the range of 174-286 nm, depending on the chitosan contents. A comparison with nanovesicles free from chitosan indicates the existence of higher contents of multilamellae structures in the composites, as well as improved stability in water.

  18. Step-by-step guide to critiquing research. Part 2: Qualitative research.

    PubMed

    Ryan, Frances; Coughlan, Michael; Cronin, Patricia

    As with a quantitative study, critical analysis of a qualitative study involves an in-depth review of how each step of the research was undertaken. Qualitative and quantitative studies are, however, fundamentally different approaches to research and therefore need to be considered differently with regard to critiquing. The different philosophical underpinnings of the various qualitative research methods generate discrete ways of reasoning and distinct terminology; however, there are also many similarities within these methods. Because of this and its subjective nature, qualitative research it is often regarded as more difficult to critique. Nevertheless, an evidenced-based profession such as nursing cannot accept research at face value, and nurses need to be able to determine the strengths and limitations of qualitative as well as quantitative research studies when reviewing the available literature on a topic.

  19. Creating History Documentaries: A Step-by-Step Guide to Video Projects in the Classroom.

    ERIC Educational Resources Information Center

    Escobar, Deborah

    This guide offers an easy introduction to social studies teachers wanting to challenge their students with creative media by bringing the past to life. The 14-step guide shows teachers and students the techniques needed for researching, scripting, and editing a historical documentary. Using a video camera and computer software, students can…

  20. The Complete Step-by-Step Guide to Designing and Teaching Online Courses

    ERIC Educational Resources Information Center

    Thormann, Joan; Zimmerman, Isa Kaftal

    2012-01-01

    In this valuable resource, experts share deep knowledge including practical "how-to" and preventive trouble-shooting tips. Instructors will learn about course design and development, instructional methods for online teaching, and student engagement and community building techniques. The book contains successful teaching strategies, guidance for…

  1. Step by Step: Biology Undergraduates' Problem-Solving Procedures during Multiple-Choice Assessment

    ERIC Educational Resources Information Center

    Prevost, Luanna B.; Lemons, Paula P.

    2016-01-01

    This study uses the theoretical framework of domain-specific problem solving to explore the procedures students use to solve multiple-choice problems about biology concepts. We designed several multiple-choice problems and administered them on four exams. We trained students to produce written descriptions of how they solved the problem, and this…

  2. Step by Step: Eating To Lower Your High Blood Cholesterol. Revised.

    ERIC Educational Resources Information Center

    National Heart, Lung, and Blood Inst. (DHHS/NIH), Bethesda, MD.

    This booklet offers advice for adults who want to lower their blood cholesterol level. The first section, "What You Need To Know about High Blood Cholesterol," discusses blood cholesterol and why it matters, what cholesterol numbers mean, and what affects blood cholesterol levels. Section 2, "What You Need To Do To Lower Blood…

  3. Certified: A Citizen's Step-by-Step Guide to Protecting Vernal Pools. 6th Edition.

    ERIC Educational Resources Information Center

    Colburn, Elizabeth A., Ed.

    The objective of this manual is to train volunteers in the process of identifying vernal pool habitat so that as many of these pools as possible can be certified by the Massachusetts Natural Heritage and Endangered Species Program. Vernal pools are a kind of temporary pond in which salamanders and other animals breed. The pools are unique…

  4. Treatment of Antibody-Mediated Renal Allograft Rejection: Improving Step by Step

    PubMed Central

    Duerr, Michael; Schönemann, Constanze; Pruß, Axel; Budde, Klemens; Waiser, Johannes

    2017-01-01

    Throughout the past years we stepwise modified our immunosuppressive treatment regimen for patients with antibody-mediated rejection (ABMR). Here, we describe three consecutive groups treated with different regimens. From 2005 until 2008, we treated all patients with biopsy-proven ABMR with rituximab (500 mg), low-dose (30 g) intravenous immunoglobulins (IVIG), and plasmapheresis (PPH, 6x) (group RLP, n = 12). Between 2009 and June 2010, patients received bortezomib (1.3 mg/m2, 4x) together with low-dose IVIG and PPH (group BLP, n = 11). In July 2010, we increased the IVIG dose and treated all subsequent patients with bortezomib, high-dose IVIG (1.5 g/kg), and PPH (group BHP, n = 11). Graft survival at three years after treatment was 73% in group BHP as compared to 45% in group BLP and 25% in group RLP. At six months after treatment median serum creatinine was 2.1 mg/dL, 2.9 mg/dL, and 4.2 mg/dL in groups BHP, BLP, and RLP, respectively (p = 0.02). Following treatment, a significant decrease of donor-specific HLA antibody (DSA) mean fluorescence intensity from 8467 ± 6876 to 5221 ± 4711 (p = 0.01) was observed in group BHP, but not in the other groups. Our results indicate that graft survival, graft function, and DSA levels could be improved along with stepwise modifications to our treatment regimen, that is, the introduction of bortezomib and high-dose IVIG treatment. PMID:28255562

  5. The Marginal Teacher: A Step-by-Step Guide to Fair Procedures for Identification and Dismissal

    ERIC Educational Resources Information Center

    Lawrence, C. Edward

    2005-01-01

    This third edition offers timely solutions for successfully dealing with marginal teachers. Lawrence illustrates the proper actions that principals should integrate into the evaluation processes to successfully gather documentation to help improve or terminate an ineffective teacher. Complete with tools and resources to streamline the evaluation…

  6. Welcome to the Future: A Practical Step-by-Step Guide to Strategic Planning.

    ERIC Educational Resources Information Center

    Kemper, Jim E.; Kemper, John J.

    1996-01-01

    Successful human resource strategic planning at colleges and universities requires that: (1) outcomes contribute to the bottom line; (2) the plan is linked to the institution's long-term strategy; and (3) the plan is simple to understand and follow. Staff retreats are essential and should involve environmental analysis, departmental analysis,…

  7. Meta-epidemiological study: a step by step approach by using R.

    PubMed

    Zhang, Zhongheng

    2016-02-09

    The results of meta-analysis are usually influenced by characteristics of component trials. These characteristics include but are not limited to sample size, publication language, quality of study design and the number of participating centers. Because systematic review and meta-analysis is considered to be evidence of the highest quality in the era of evidence-based medicine, characteristics that may bias the results of meta-analysis should be fully investigated. Meta-epidemiological study aims to investigate the impact of study design characteristics on treatment effect. The article introduces how to perform meta-epidemiological study by using R software. There are several methodological approaches to perform meta-epidemiological study, depending on whether there is heterogeneity between meta-analyses and between trials. When there is no significant heterogeneity, these results would be similar. This article is protected by copyright. All rights reserved.

  8. A Step-by-Step Picture of Pulsed (Time-Domain) NMR.

    ERIC Educational Resources Information Center

    Schwartz, Leslie J.

    1988-01-01

    Discusses a method for teaching time pulsed NMR principals that are as simple and pictorial as possible. Uses xyz coordinate figures and presents theoretical explanations using a Fourier transformation spectrum. Assumes no previous knowledge of quantum mechanics for students. Usable for undergraduates. (MVL)

  9. Street-Smart Career Guide: A Step-by-Step Program for Your Career Development.

    ERIC Educational Resources Information Center

    Pedersen, Laura

    In this guide, the secret of career success is recognizing individual talents or specific knowledge and integrating the thinking and behavior of entrepreneurs into the daily routine or job. Part I, Career Planning for Tomorrow's Marketplace, sets the scene by describing the information age, technology, and the rise of global consumerism. It…

  10. Algal biomass conversion to bioethanol - a step-by-step assessment.

    PubMed

    Harun, Razif; Yip, Jason W S; Thiruvenkadam, Selvakumar; Ghani, Wan A W A K; Cherrington, Tamara; Danquah, Michael K

    2014-01-01

    The continuous growth in global population and the ongoing development of countries such as China and India have contributed to a rapid increase in worldwide energy demand. Fossil fuels such as oil and gas are finite resources, and their current rate of consumption cannot be sustained. This, coupled with fossil fuels' role as pollutants and their contribution to global warming, has led to increased interest in alternative sources of energy production. Bioethanol, presently produced from energy crops, is one such promising alternative future energy source and much research is underway in optimizing its production. The economic and temporal constraints that crop feedstocks pose are the main downfalls in terms of the commercial viability of bioethanol production. As an alternative to crop feedstocks, significant research efforts have been put into utilizing algal biomass as a feedstock for bioethanol production. Whilst the overall process can vary, the conversion of biomass to bioethanol usually contains the following steps: (i) pretreatment of feedstock; (ii) hydrolysis; and (iii) fermentation of bioethanol. This paper reviews different technologies utilized in the pretreatment and fermentation steps, and critically assesses their applicability to bioethanol production from algal biomass. Two different established fermentation routes, single-stage fermentation and two-stage gasification/fermentation processes, are discussed. The viability of algal biomass as an alternative feedstock has been assessed adequately, and further research optimisation must be guided toward the development of cost-effective scalable methods to produce high bioethanol yield under optimum economy.

  11. A Three-Step Reinforcer Identification Framework: A Step-by-Step Process

    ERIC Educational Resources Information Center

    Da Fonte, M. Alexandra; Boesch, Miriam C.; Edwards-Bowyer, Meghan E.; Restrepo, Madeleine W.; Bennett, Brittany P.; Diamond, Gwendolyn P.

    2016-01-01

    The delivery of reinforcers is a research-based practice that can be used to increase student engagement within the classroom and promote skill acquisition. Reinforcers also play an integral role in the instructional planning of students with severe disabilities. Using reinforcement involves using preference assessment to identify potential…

  12. Note: A single-chamber tool for plasma activation and surface functionalization in microfabrication

    PubMed Central

    Bowman, Adam J.; Scherrer, Joseph R.; Reiserer, Ronald S.

    2015-01-01

    We present a simple apparatus for improved surface modification of polydimethylsiloxane (PDMS) microfluidic devices. A single treatment chamber for plasma activation and chemical/physical vapor deposition steps minimizes the time-dependent degradation of surface activation that is inherent in multi-chamber techniques. Contamination and deposition irregularities are also minimized by conducting plasma activation and treatment phases in the same vacuum environment. An inductively coupled plasma driver allows for interchangeable treatment chambers. Atomic force microscopy confirms that silane deposition on PDMS gives much better surface quality than standard deposition methods, which yield a higher local roughness and pronounced irregularities in the surface. PMID:26133881

  13. Note: A single-chamber tool for plasma activation and surface functionalization in microfabrication

    SciTech Connect

    Bowman, Adam J.; Scherrer, Joseph R.; Reiserer, Ronald S.

    2015-06-15

    We present a simple apparatus for improved surface modification of polydimethylsiloxane (PDMS) microfluidic devices. A single treatment chamber for plasma activation and chemical/physical vapor deposition steps minimizes the time-dependent degradation of surface activation that is inherent in multi-chamber techniques. Contamination and deposition irregularities are also minimized by conducting plasma activation and treatment phases in the same vacuum environment. An inductively coupled plasma driver allows for interchangeable treatment chambers. Atomic force microscopy confirms that silane deposition on PDMS gives much better surface quality than standard deposition methods, which yield a higher local roughness and pronounced irregularities in the surface.

  14. Project Notes

    ERIC Educational Resources Information Center

    School Science Review, 1978

    1978-01-01

    Presents sixteen project notes developed by pupils of Chipping Norton School and Bristol Grammar School, in the United Kingdom. These Projects include eight biology A-level projects and eight Chemistry A-level projects. (HM)

  15. A note on chromospheric fine structure at active region polarity boundaries.

    NASA Technical Reports Server (NTRS)

    Prata, S. W.

    1971-01-01

    High resolution H-alpha filtergrams from Big Bear Solar Observatory reveal that some filamentary features in active regions have fine structure and hence magnetic field transverse to the gross structure and the zero longitudinal field line. These features are distinct from the usual active region filament, in which fine structure, magnetic field, and filament are all parallel to the zero longitudinal field line. The latter occur on boundaries between regions of weaker fields, while the former occur at boundaries between regions of stronger field.

  16. Blue Note

    ScienceCinema

    Murray Gibson

    2016-07-12

    Argonne's Murray Gibson is a physicist whose life's work includes finding patterns among atoms. The love of distinguishing patterns also drives Gibson as a musician and Blues enthusiast."Blue" notes are very harmonic notes that are missing from the equal temperament scale.The techniques of piano blues and jazz represent the melding of African and Western music into something totally new and exciting.

  17. Blue Note

    SciTech Connect

    Murray Gibson

    2007-04-27

    Argonne's Murray Gibson is a physicist whose life's work includes finding patterns among atoms. The love of distinguishing patterns also drives Gibson as a musician and Blues enthusiast."Blue" notes are very harmonic notes that are missing from the equal temperament scale.The techniques of piano blues and jazz represent the melding of African and Western music into something totally new and exciting.

  18. Student's Reflections on Their Learning and Note-Taking Activities in a Blended Learning Course

    ERIC Educational Resources Information Center

    Nakayama, Minoru; Mutsuura, Kouichi; Yamamoto, Hiroh

    2016-01-01

    Student's emotional aspects are often discussed in order to promote better learning activity in blended learning courses. To observe these factors, course participant's self-efficacy and reflections upon their studies were surveyed, in addition to the surveying of the metrics of student's characteristics during a Bachelor level credit course.…

  19. Making Algebra Come Alive: Student Activities & Teacher Notes. Math Assessment Series.

    ERIC Educational Resources Information Center

    Posamentier, Alfred S.

    This book contains a set of versatile enrichment exercises that cover a very broad range of mathematical topics and applications in algebra from the Moebius strip to the googol. Several criteria have been used in developing the activities and selecting the topics that are included. All of them bear heavily and equally on concerns for curriculum…

  20. Making Pre-Algebra Come Alive: Student Activities & Teacher Notes. Math Assessment Series.

    ERIC Educational Resources Information Center

    Posamentier, Alfred S.

    This book contains a set of versatile enrichment exercises that cover a very broad range of mathematical topics and applications in pre-algebra from the Moebius strip to the googol. Several criteria have been used in developing the activities and selecting the topics that are included. All of them bear heavily and equally on concerns for…

  1. A note on the utilization of common support activities and relapse following substance abuse treatment.

    PubMed

    Johnsen, E; Herringer, L G

    1993-01-01

    We examined the relationship between involvement with three common social support activities and abstinence rates among former patients (N = 50) of an inpatient substance abuse treatment facility. Attendance at aftercare meetings and attendance at Alcoholics Anonymous or Narcotics Anonymous meetings were significantly related to posttreatment abstinence, whereas family participation in recovery did not, by itself, significantly predict continued abstinence. Examining these factors together, we found that the abstinence rate increased linearly as more supports were used.

  2. Notes on the Diet of Reproductively Active Male Rafinesque's Big Eared Bats

    SciTech Connect

    Menzel, M.A.; Carter, T.C.; Menzel, J.M.; Edwards, J.W.; Ford, W.M.

    2002-01-01

    Diet examination through the use of fecal samples, of five reproductively active male Rafinesque's big-eared bats from the Upper Coastal Plain of South Carolina during August and September 1999. Diets of these individuals in upland pine stands were similar to diets of Rafinesque's big-eared bats in bottomland and upland hardwood habitats. Although fecal samples had three insect orders, the diet consisted primarily of lepidopterans.

  3. A Note on the Viability of Gaseous Ionization in Active Galaxies by Fast Shocks

    NASA Astrophysics Data System (ADS)

    Laor, Ari

    1998-04-01

    Morphological and spectroscopic evidence suggests that shocks may affect the spatial and velocity distributions of gas in the narrow-line region (NLR) and the extended NLR of some active galaxies. It thus seemed plausible that shocks may energize the NLR also. The observed emission-line ratios strongly favor photoionization as the heating source for this gas, but it is not clear whether the ionizing radiation is generated in the NLR by ``photoionizing shocks'' or whether the ionizing radiation originates at the central continuum source. Here I point out that shocks are highly inefficient in producing line emission. Shocks in the NLR can convert at most ~10-6 of the rest mass to ionizing radiation, compared with a maximum conversion efficiency of ~10-1 for the central continuum source. The required mass flow rate through ``photoionizing shocks'' in the NLR is thus a few orders of magnitude higher than the mass accretion rate required to power the NLR by the central continuum source. Since gravity appears to dominate the NLR cloud dynamics, shocks must lead to an inflow, and the implied high inflow rates can be ruled out in most active galaxies. NLR dynamics driven by a thermal wind or by some jet configurations may produce the mass flux through shocks required for photoionizing shocks to be viable, but the mass flux inward from the NLR must be kept ~100-1000 times smaller. Photoionizing shocks are a viable mechanism in very low luminosity active galaxies if they are highly sub-Eddington (<~10-4) and if they convert mass to radiation with a very low efficiency (<~10-4).

  4. Note: A three-dimension active vibration isolator for precision atom gravimeters

    SciTech Connect

    Zhou, Min-Kang; Xiong, Xin; Chen, Le-Le; Cui, Jia-Feng; Duan, Xiao-Chun; Hu, Zhong-Kun

    2015-04-15

    An ultra-low frequency active vibration isolator, simultaneously suppressing three-dimensional vibration noise, is demonstrated experimentally. The equivalent natural period of the isolator is 100 s and 12 s for the vertical and horizontal direction, respectively. The vibration noise in the vertical direction is about 50 times reduced during 0.2 and 2 Hz, and 5 times reduced in the other two orthogonal directions in the same frequency range. This isolator is designed for atom gravimeters, especially suitable for the gravimeter whose sensitivity is limited by vibration couplings.

  5. Technical note: A procedure to estimate glucose requirements of an activated immune system in steers.

    PubMed

    Kvidera, S K; Horst, E A; Abuajamieh, M; Mayorga, E J; Sanz Fernandez, M V; Baumgard, L H

    2016-11-01

    Infection and inflammation impede efficient animal productivity. The activated immune system ostensibly requires large amounts of energy and nutrients otherwise destined for synthesis of agriculturally relevant products. Accurately determining the immune system's in vivo energy needs is difficult, but a better understanding may facilitate developing nutritional strategies to maximize productivity. The study objective was to estimate immune system glucose requirements following an i.v. lipopolysaccharide (LPS) challenge. Holstein steers (148 ± 9 kg; = 15) were jugular catheterized bilaterally and assigned to 1 of 3 i.v.

  6. TECHNICAL NOTE: Electrically aligned cellulose film for electro-active paper and its piezoelectricity

    NASA Astrophysics Data System (ADS)

    Yun, Sungryul; Jang, Sangdong; Yun, Gyu-Young; Kim, Jaehwan

    2009-11-01

    Electrically aligned regenerated cellulose films were fabricated and the effect of applied electric field was investigated for the piezoelectricity of electro-active paper (EAPap). The EAPap was fabricated by coating gold electrodes on both sides of regenerated cellulose film. The cellulose film was prepared by dissolving cotton pulp in LiCl/N,N-dimethylacetamide solution followed by a cellulose chain regeneration process. During the regeneration process an external electric field was applied in the direction of mechanical stretching. Alignment of cellulose fiber chains was investigated as a function of applied electric field. The material characteristics of the cellulose films were analyzed by using an x-ray diffractometer, a field emission scanning electron microscope and a high voltage electron microscope. The application of external electric fields was found to induce formation of nanofibers in the cellulose, resulting in an increase in the crystallinity index (CI) values. It was also found that samples with higher CI values showed higher in-plane piezoelectric constant, d31, values. The piezoelectricity of the current EAPap films was measured to be equivalent or better than that of ordinary PVDF films. Therefore, an external electric field applied to a cellulose film along with a mechanical stretching during the regeneration process can enhance the piezoelectricity.

  7. Teaching Activities on Horizontal Nuclear Proliferation.

    ERIC Educational Resources Information Center

    Zola, John

    1990-01-01

    Provides learning activities concerning the horizontal proliferation of nuclear weapons. Includes step-by-step directions for four activities: (1) the life cycle of nuclear weapons; (2) nuclear nonproliferation: pros and cons; (3) the nuclear power/nuclear weapons connection; and (4) managing nuclear proliferation. (NL)

  8. Apparatus Notes.

    ERIC Educational Resources Information Center

    Eaton, Bruce G., Ed.

    1980-01-01

    This collection of notes describes (1) an optoelectronic apparatus for classroom demonstrations of mechanical laws, (2) a more efficient method for demonstrated nuclear chain reactions using electrically energized "traps" and ping-pong balls, and (3) an inexpensive demonstration for qualitative analysis of temperature-dependent resistance. (CS)

  9. Classroom Notes

    ERIC Educational Resources Information Center

    International Journal of Mathematical Education in Science and Technology, 2007

    2007-01-01

    In this issue's "Classroom Notes" section, the following papers are described: (1) "Sequences of Definite Integrals" by T. Dana-Picard; (2) "Structural Analysis of Pythagorean Monoids" by M.-Q Zhan and J. Tong; (3) "A Random Walk Phenomenon under an Interesting Stopping Rule" by S. Chakraborty; (4) "On Some Confidence Intervals for Estimating the…

  10. Biology Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1984

    1984-01-01

    Presents information on the teaching of nutrition (including new information relating to many current O-level syllabi) and part 16 of a reading list for A- and S-level biology. Also includes a note on using earthworms as a source of material for teaching meiosis. (JN)

  11. Classroom Notes

    ERIC Educational Resources Information Center

    International Journal of Mathematical Education in Science and Technology, 2007

    2007-01-01

    In this issue's "Classroom Notes" section, the following papers are discussed: (1) "Constructing a line segment whose length is equal to the measure of a given angle" (W. Jacob and T. J. Osler); (2) "Generating functions for the powers of Fibonacci sequences" (D. Terrana and H. Chen); (3) "Evaluation of mean and variance integrals without…

  12. Application note :

    SciTech Connect

    Russo, Thomas V.

    2013-08-01

    The development of the XyceTM Parallel Electronic Simulator has focused entirely on the creation of a fast, scalable simulation tool, and has not included any schematic capture or data visualization tools. This application note will describe how to use the open source schematic capture tool gschem and its associated netlist creation tool gnetlist to create basic circuit designs for Xyce, and how to access advanced features of Xyce that are not directly supported by either gschem or gnetlist.

  13. Basic Skills and Activities Compendium. Instructional Objectives and Matching Activities for Working with Severely and Profoundly Mentally Retarded Children.

    ERIC Educational Resources Information Center

    City Univ. of New York, NY. Center for Advanced Study in Education.

    The kit contains instructional objectives and matching activities for working with severely and profoundly mentally retarded children. Activities are classified into three color coded skill areas - sensory stimulation, motor development, and language development. Each card includes the name of the activity, objectives, and step-by-step procedures.…

  14. Editor's Note.

    PubMed

    Alberts, Bruce

    2011-05-27

    The Research Article "A bacterium that can grow by using arsenic instead of phosphorus" by F. Wolfe-Simon et al., published online 2 December 2010, was the subject of extensive discussion and criticism following its online publication. Science received a wide range of correspondence that raised specific concerns about the Research Article's methods and interpretations. Eight Technical Comments that represent the main concerns, as well as a Technical Response by Wolfe-Simon et al., are published online in Science Express at the addresses listed in this note. They have been peer-reviewed and revised according to Science's standard procedure.

  15. Teaching Notes

    NASA Astrophysics Data System (ADS)

    2001-07-01

    If you would like to contribute a teaching note for any of these sections please contact ped@iop.org Contents: LET'S INVESTIGATE: Bows and arrows STARTING OUT: A late start ON THE MAP: A South African school making a world of difference TECHNICAL TRIMMINGS: May the force be with you an easily constructed force sensor Modelling Ultrasound A-scanning with the Pico Technology ADC-200 Virtual Instrument PHYSICS ON A SHOESTRING: Sugar cube radioactivity models CURIOSITY: Euler's disk MY WAY: Why heavy things don't fall faster

  16. Editors' note

    NASA Astrophysics Data System (ADS)

    Denker, Carsten; Feller, Alex; Schmidt, Wolfgang; von der Lühe, Oskar

    2012-11-01

    This topical issue of Astronomische Nachrichten/Astronomical Notes is a collection of reference articles covering the GREGOR solar telescope, its science capabilities, its subsystems, and its dedicated suite of instruments for high-resolution observations of the Sun. Because ground-based telescopes have life spans of several decades, it is only natural that they continuously reinvent themselves. Literally, the GREGOR telescope builds on the foundations of the venerable Gregory-Coudé Telescope (GCT) at Observatorio del Teide, Tenerife, Spain. Acknowledging the fact that new discoveries in observational solar physics are driven by larger apertures to collect more photons and to scrutinize the Sun in finer detail, the GCT was decommissioned and the building was made available to the GREGOR project.

  17. NCTM Student Math Notes.

    ERIC Educational Resources Information Center

    Maletsky, Evan, Ed.; Yunker, Lee E., Ed.

    1986-01-01

    Five sets of activities for students are included in this document. Each is designed for use in junior high and secondary school mathematics instruction. The first Note concerns mathematics on postage stamps. Historical procedures and mathematicians, metric conversion, geometric ideas, and formulas are among the topics considered. Successful…

  18. Student Math Notes.

    ERIC Educational Resources Information Center

    Maletsky, Evan, Ed.

    1985-01-01

    Five sets of activities for students are included in this document. Each is designed for use in junior high and secondary school mathematics instruction. The first "Note" concerns magic squares in which the numbers in every row, column, and diagonal add up to the same sum. An etching by Albrecht Durer is presented, with four questions followed by…

  19. Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1987

    1987-01-01

    Describes 20 teaching activities and experiments appropriate for use with various secondary school science classes. Instructional activities include the study of catalase, raising bees, a game about equilibrium, spectrometers, lead iodide, resonance, graphing, and electromagnetic waves. (TW)

  20. Physics Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1981

    1981-01-01

    Presents activities, experiments, demonstrations, and equipment for physics instruction, including computer applications of sports biomechanics, vibrating magnetometer, alternative uses for an environmental comparator, CMOS integrated circuit logic tutor, and an activity demonstrating positive and negative leakage. (JN)

  1. Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1990

    1990-01-01

    Included are 30 science activities that include computer monitoring, fieldwork, enzyme activity, pH, drugs, calorimeters, Raoult's Law, food content, solubility, electrochemistry, titration, physical properties of materials, gel filtration, energy, concepts in physics, and electricity. (KR)

  2. Biology Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1984

    1984-01-01

    Describes mushroom growing as a school project, a method for illustrating need for carbon dioxide in photosynthesis, construction of a simple phytoplankton sampler, cell division activity using playing cards, blood separation activity, measurement of adaptation and selection pressures, computations in field ecology, and an activity demonstrating…

  3. Editorial Note

    NASA Astrophysics Data System (ADS)

    van der Meer, F.; Ommen Kloeke, E.

    2015-07-01

    With this editorial note we would like to update you on the performance of the International Journal of Applied Earth Observation and Geoinformation (JAG) and inform you about changes that have been made to the composition of the editorial team. Our Journal publishes original papers that apply earth observation data for the management of natural resources and the environment. Environmental issues include biodiversity, land degradation, industrial pollution and natural hazards such as earthquakes, floods and landslides. As such the scope is broad and ranges from conceptual and more fundamental work on earth observation and geospatial sciences to the more problem-solving type of work. When I took over the role of Editor-in-Chief in 2012, I together with the Publisher set myself the mission to position JAG in the top-3 of the remote sensing and GIS journals. To do so we strived at attracting high quality and high impact papers to the journal and to reduce the review turnover time to make JAG a more attractive medium for publications. What has been achieved? Have we reached our ambitions? We can say that: The submissions have increased over the years with over 23% for the last 12 months. Naturally not all may lead to more papers, but at least a portion of the additional submissions should lead to a growth in journal content and quality.

  4. Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1987

    1987-01-01

    Contains 31 activities and experiments from the biological and physical sciences. Addresses such areas as reproduction, biotechnology, ecology, proteins, nitrates, aerosols, metal crystallinity, circuit boards, and photoswitching. (ML)

  5. Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1986

    1986-01-01

    Describes 26 different activities, experiments, demonstrations, and computer simulations in various topics in science. Includes instructional activities dealing with mural ecology, surface area/volume ratios, energy transfer in ecosystems, electrochemical simulations, alternating and direct current, terminal velocity, measuring the size of the…

  6. Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1985

    1985-01-01

    Presents biology, chemistry, physics, and health activities, experiments, demonstrations, and computer programs. Includes mechanism of stomatal opening, using aquatic plants to help demonstrate chemical buffering, microbial activity/contamination in milk samples, computer computation of fitness scores, reservoir project, complexes of transition…

  7. Biology Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1981

    1981-01-01

    Presents a computer program for analyzing diets, a game designed to supplement a topic on insects, a technique for demonstrating the role of ethene in fruit ripening, an apparatus for removing arthropods from soil samples, activities using cichlids, and an activity on bonds stabilizing protein structure. (JN)

  8. English for Everyday Activities: A Picture Process Dictionary.

    ERIC Educational Resources Information Center

    Zwier, Lawrence J.

    These books are designed to help English-as-a-Second-Language (ESL) students learn the skills they need to communicate the step-by-step aspects of daily activities. Unlike most picture dictionaries, this is a verb-based multi-skills program that uses a student text with a clear and colorful pictorial detail as a starting point and focuses on the…

  9. Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1990

    1990-01-01

    Presented are 29 science activities for secondary school science instruction. Topic areas include botany, genetics, biochemistry, anatomy, entomology, molecular structure, spreadsheets, chemistry, mechanics, astronomy, relativity, aeronautics, instrumentation, electrostatics, quantum mechanics, and laboratory interfacing. (CW)

  10. Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1989

    1989-01-01

    Twenty-two activities are presented. Topics include: acid rain, microcomputers, fish farming, school-industry research projects, enzymes, equilibrium, assessment, science equipment, logic, Archimedes principle, electronics, optics, and statistics. (CW)

  11. Chemistry Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1983

    1983-01-01

    Presents background information, laboratory procedures, classroom materials/activities, and chemistry experiments. Topics include sublimation, electronegativity, electrolysis, experimental aspects of strontianite, halide test, evaluation of present and future computer programs in chemistry, formula building, care of glass/saturated calomel…

  12. Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1985

    1985-01-01

    Presents 23 experiments, activities, field projects and computer programs in the biological and physical sciences. Instructional procedures, experimental designs, materials, and background information are suggested. Topics include fluid mechanics, electricity, crystals, arthropods, limpets, acid neutralization, and software evaluation. (ML)

  13. Physics Notes

    ERIC Educational Resources Information Center

    School Science Review, 1976

    1976-01-01

    Described are 13 physics experiments/demonstrations applicable to introductory physics courses. Activities include: improved current balance, division circuits, liquid pressure, convection, siphons, oscillators and modulation, electrical resistance, soap films, Helmholtz coils, radioactive decay, and springs. (SL)

  14. Chemistry Notes

    ERIC Educational Resources Information Center

    School Science Review, 1976

    1976-01-01

    Described are eight chemistry experiments and demonstrations applicable to introductory chemistry courses. Activities include: measure of lattice enthalpy, Le Chatelier's principle, decarboxylation of soap, use of pocket calculators in pH measurement, and making nylon. (SL)

  15. Chemistry Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1980

    1980-01-01

    Describes equipment, activities, and experiments useful in chemistry instruction, including among others, a rapid method to determine available chlorine in bleach, simple flame testing apparatus, and a simple apparatus demonstrating the technique of flash photolysis. (SK)

  16. NIDA Notes

    MedlinePlus

    ... Adolescent Brain Comorbidity College-Age & Young Adults Criminal Justice Drugged Driving Drug Testing Drugs and the Brain ... Meetings & Events Media Guide About NIDA Director's Page Organization Legislative Activities Advisory Boards & Groups Working at NIDA ...

  17. Chemistry Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1981

    1981-01-01

    Describes 13 activities, experiments and demonstrations, including the preparation of iron (III) chloride, simple alpha-helix model, investigating camping gas, redox reactions of some organic compounds, a liquid crystal thermometer, and the oxidation number concept in organic chemistry. (JN)

  18. Science Notes.

    ERIC Educational Resources Information Center

    Thurman, Shirley; And Others

    1988-01-01

    Describes 36 science activities. Topics include: osmosis, fermentation, anhydrobiotic organisms, breathing monitors, trypsin, weeds, amyloplasts, electrolysis, polarimeters, ethene ripening of fruit, colorimetry, diffusion, redox reactions, equilibria, acid-base relationships, electricity, power, resonance, measurement, parallax, amplifiers,…

  19. Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1984

    1984-01-01

    Presents 28 activities, games, demonstrations, experiments, and computer programs for biology, chemistry, physics, and conservation education. Background information, laboratory procedures, equipment lists, and instructional strategies are included. Topics include nature conservation, chickens in school, human anatomy, nitrogen cycle, mechanism…

  20. Editors' note

    NASA Astrophysics Data System (ADS)

    2015-03-01

    The widespread eutrophication of coastal waters clearly involves increased nitrogen loads, in most cases with nitrogen derived from human activities on contributing watersheds. This has prompted regulators, managers, and other stakeholders to set standards for water quality that involve lowering nitrogen loads to estuaries and other coastal waters. To carry out the proscribed lowering of nitrogen loads there are a number of options. In many instances and sites with high human density and intense activity, advanced wastewater treatment plants are unavoidable, but such environmental engineering approaches are costly. There are many coastal zones with lower population densities where other, less costly alternative strategies might be less expensive and more attuned to "green" approaches.

  1. Physics Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1984

    1984-01-01

    Discusses: (1) Brewster's angle in the elementary laboratory; (2) color mixing by computer; (3) computer iteration at A-level; (4) a simple probe for pressure measurement; (5) the measurement of distance using a laser; and (6) an activity on Archimede's principle. (JN)

  2. Chemistry Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1982

    1982-01-01

    Presents laboratory procedures, classroom materials/activities, and demonstrations, including: vapor pressure of liquid mixtures and Raoult's law; preparation/analysis of transition metal complexes of ethylammonium chloride; atomic structure display using a ZX81 (includes complete program listing); "pop-up" models of molecules and ions;…

  3. Biology Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1983

    1983-01-01

    Describes laboratory procedures, demonstrations, and classroom activities/materials, including chi-square tests on a microcomputer, an integrated biology game, microscope slides of leaf stomata, culturing soil nematodes, technique for watering locust egg-laying tubes, hazards of biological chemicals (such as benzene, benzidene, calchicine,…

  4. Science Notes.

    ERIC Educational Resources Information Center

    Piearce, Trevor; And Others

    1988-01-01

    Provides explanations of 15 experiments, laboratory activities, demonstrations, and lessons for use in instruction. Includes information on Daphnia, wild garlic, crystals, gas chromatographs, bleaches, alcohols, reactivity series, chemistry formula, electronic keyboards and waveforms, interference and diffraction gravity, Moire fringe patterns,…

  5. Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1984

    1984-01-01

    Presents 26 activities, experiments, demonstrations, games, and computer programs for biology, chemistry, and physics. Background information, laboratory procedures, equipment lists, and instructional strategies are given. Topics include eye measurements, nutrition, soil test tube rack, population dynamics, angular momentum, transition metals,…

  6. Biology Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1983

    1983-01-01

    Describes laboratory procedures, demonstrations, and classroom activities/materials, including water relation exercise on auxin-treated artichoke tuber tissue; aerobic respiration in yeast; an improved potometer; use of mobiles in biological classification, and experiments on powdery mildews and banana polyphenol oxidase. Includes reading lists…

  7. Chemistry Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1981

    1981-01-01

    Outlines a variety of laboratory procedures, classroom materials, and demonstrations including a demonstration of the Markownikoff rule; blue bottle reaction and photosynthesis; a cheaper version of Fehling's solution; chemical formulas for younger students; chemical bonding and periodicity cards; optical activity demonstrations; and six others.…

  8. Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1985

    1985-01-01

    Activities, experiments, computer programs, equipment, procedures, demonstrations, and teaching techniques are provided for a wide variety of topics in the biological and physical sciences. They include an improved apparatus for measuring rate of photosynthesis, procedures for making rainbows and measuring stomatal openings, and others. (JN)

  9. Chemistry Notes

    ERIC Educational Resources Information Center

    School Science Review, 1972

    1972-01-01

    Short articles on the determination of the activation energy of the thiosulphate-acid reaction, an experiment on hydrolysis of similar metal salt solutions, the preparation and electrolytic properties of iodine monochloride and iodine trochloride, and instructions for apparatus enabling laboratory study of the thermal cracking of ethylbenzene. (AL)

  10. Chemistry Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1982

    1982-01-01

    Presents background information, laboratory procedures, classroom materials/activities, and experiments for chemistry. Topics include superheavy elements, polarizing power and chemistry of alkali metals, particulate carbon from combustion, tips for the chemistry laboratory, interesting/colorful experiments, behavior of bismuth (III) iodine, and…

  11. Biology Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1982

    1982-01-01

    Describes laboratory procedures, demonstrations, and classroom activities/materials, including use of dwarf cichlids (fishes) in secondary school biology, teaching edge effects on stomatal diffusion, computer program on effects of selection on gene frequencies, biological oxidation/reduction reactions, short cuts with Drosophila, computer program…

  12. Biology Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1980

    1980-01-01

    Describes equipment, activities, and experiments useful in biology and environmental education instruction, including, among others, sampling in ecology using an overhead projector, the slide finder as an aid to microscopy, teaching kidney function, and teaching wildlife conservation-sand dune systems. (SK)

  13. Biology Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1982

    1982-01-01

    Describes laboratory procedures, demonstrations, and classroom activities/materials, including rapid peat-depth surveying; leaf-flotation method for measuring photosynthesis, an educational game demonstrating basis of protein synthesis, daffodil phototropism; chromatography apparatus; egg white digestion, and chromatography apparatus. Also…

  14. Chemistry Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1983

    1983-01-01

    Presents chemistry experiments, laboratory procedures, demonstrations, teaching suggestions, and classroom materials/activities. These include: game for teaching ionic formulas; method for balancing equations; description of useful redox series; computer programs (with listings) for water electrolysis simulation and for determining chemical…

  15. Physics Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1983

    1983-01-01

    Discusses the Rugby clock as a source of project material, use of ZX81 for experimental science, computer dice analog, oil recovery from reservoirs, and computer simulation of Thompson's experiment for determining e/m for an electron. Activities/procedures are provided when applicable. Also presents questions (and answers) related to time-coded…

  16. Chemistry Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1983

    1983-01-01

    Presents chemistry experiments, laboratory procedures, demonstrations, and classroom materials/activities. These include: experiments on colloids, processing of uranium ore, action of heat on carbonates; color test for phenols and aromatic amines; solvent properties of non-electrolytes; stereoscopic applications/methods; a valency balance;…

  17. Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1985

    1985-01-01

    Presents 23 experiments, demonstrations, activities, and computer programs in biology, chemistry, and physics. Topics include lead in petrol, production of organic chemicals, reduction of water, enthalpy, X-ray diffraction model, nuclear magnetic resonance spectroscopy, computer simulation for additive mixing of colors, Archimedes Principle, and…

  18. Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1990

    1990-01-01

    Presented are 25 science activities on colorations of prey, evolution, blood, physiology, nutrition, enzyme kinetics, leaf pigments, analytical chemistry, milk, proteins, fermentation, surface effects of liquids, magnetism, drug synthesis, solvents, wintergreen synthesis, chemical reactions, multicore cables, diffraction, air resistance,…

  19. Science Notes.

    ERIC Educational Resources Information Center

    Murray, A. J. S.; And Others

    1988-01-01

    Presents 31 science activities for use with high school or college science classes. Topics included are: chromatography, ecology, invertebrates, enzymes, genetics, botany, creep, crystals, diffusion, computer interfaces, acid rain, teaching techniques, chemical reactions, waves, electric fields, rainbows, electricity, magnetic fields, and a Pitot…

  20. Physics Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1980

    1980-01-01

    Describes equipment, activities, and experiments useful in physics instruction, including among others, a list of articles relating to physics topics, computer interface that makes a computer cost effective, use of a guitar in vibrating string experiments, and photoelectric aids to the measurement of distance, speed, velocity, and acceleration.…

  1. Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1986

    1986-01-01

    Describes activities, games, experiments, demonstrations, and computer-oriented exercises in all science areas. Topics include energy flow through a marine ecosystem, using 2,4-dichlorophenoxyethanoic acid to demonstrate translocation in plants, use of the dichotomous key, use of leaf yeasts to monitor atmospheric pollution, and others. (JN)

  2. Biology Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1978

    1978-01-01

    Presents experiments, demonstrations, activities and ideas relating to various fields of biology to be used in biology courses in secondary schools. Among those experiments presented are demonstrating the early stages of ferns and mosses and simple culture methods for fern prothalli. (HM)

  3. Okefenokee Notes.

    ERIC Educational Resources Information Center

    Burton, Patricia E.

    1985-01-01

    A four-day field trip to Okefenokee swamp was a learning experience filled with variety for sixth grade students from North Carolina. Academic preparation, site activities (camping, observing, exploring, wading, and canoeing), and resource materials (for interested groups throughout the United States) are discussed. (DH)

  4. Oscillation regimes of a solid-state ring laser with active beat-note stabilization: From a chaotic device to a ring-laser gyroscope

    SciTech Connect

    Schwartz, Sylvain; Feugnet, Gilles; Pocholle, Jean-Paul; Lariontsev, Evguenii

    2007-08-15

    We report an experimental and theoretical study of a rotating diode-pumped Nd-YAG ring laser with active beat-note stabilization. Our experimental setup is described in the usual Maxwell-Bloch formalism. We analytically derive a stability condition and some frequency response characteristics for the solid-state ring-laser gyroscope, illustrating the important role of mode coupling effects on the dynamics of such a device. Experimental data are presented and compared with the theory on the basis of realistic laser parameters, showing very good agreement. Our results illustrate the duality between the very rich nonlinear dynamics of the diode-pumped solid-state ring laser (including chaotic behavior) and the possibility to obtain a very stable beat note, resulting in a potentially new kind of rotation sensor.

  5. HEPS Inventory Tool: An Inventory Tool Including Quality Assessment of School Interventions on Healthy Eating and Physical Activity

    ERIC Educational Resources Information Center

    Dadaczynski, Kevin; Paulus, Peter; de Vries, Nanne; de Ruiter, Silvia; Buijs, Goof

    2010-01-01

    The HEPS Inventory Tool aims to support stakeholders working in school health promotion to promote high quality interventions on healthy eating and physical activity. As a tool it provides a step-by-step approach on how to develop a national or regional inventory of existing school based interventions on healthy eating and physical activity. It…

  6. Research Note: Physical Activity Levels in Elementary-School Physical Education: A Comparison of Swimming and Nonswimming Classes

    ERIC Educational Resources Information Center

    Cardon, Greet; Verstraete, Stefanie; De Clercq, Dirk; De Bourdeaudhuij, Ilse

    2004-01-01

    The main goal of the current study was to compare physical activity levels during swimming and nonswimming elementary physical education classes. We conducted a preliminary study and found that the System for Observing Fitness Instruction Time (SOFIT) could be used to register physical activity engagement levels in swimming classes. Thirty-nine…

  7. A Step-by-Step Way to Sell Yourself--and Your Boss--on the Value of Individualized Instruction

    ERIC Educational Resources Information Center

    Maginn, Michael

    1976-01-01

    For detailed information that needs to be retrieved occasionally before being memorized, individualized instruction is the key. Unfortunately, many executives confuse the term with the program instruction which they studied in the early 1960s. Information is provided to help the trainer convince management that self-paced learning succeeds, and…

  8. Story Drama in the Special Needs Classroom: Step-by-Step Lesson Plans for Teaching through Dramatic Play

    ERIC Educational Resources Information Center

    Carleton, Jessica Perich

    2012-01-01

    Introducing drama to the learning experience is guaranteed to enrich a child's development, and is an especially effective approach for children with special educational needs, including those with autism spectrum disorders. This practical handbook offers teachers an array of simple and easy-to-implement theatrical techniques that will enhance…

  9. Title IX Indian Education Toolkit. A Step-by-Step Guide to the Title IX Indian Education Formula Grant.

    ERIC Educational Resources Information Center

    Beller, Floyd

    Title IX is a federal Indian Education Formula Grant Program approved in 1972 and reauthorized five times, most recently in 1994. Title IX formula grants assist groups in providing sound educational programs and opportunities for American Indian and Alaska Native students. A 1997-98 survey of Title IX grantees revealed their need for help in…

  10. Teaching with Emotional Intelligence: A Step-By-Step Guide for Higher and Further Education Professionals. 2nd Edition

    ERIC Educational Resources Information Center

    Mortiboys, Alan

    2011-01-01

    The way teachers shape and handle their own feelings and those of their learners is central to the success of learning. Now in its second edition, "Teaching with Emotional Intelligence" shows how to manage this influential yet neglected area of learning and teaching. This practical book looks at how lecturers and teachers can develop and use their…

  11. How to Develop Children as Researchers: A Step-by-Step Guide to Teaching the Research Process

    ERIC Educational Resources Information Center

    Kellett, Mary

    2005-01-01

    The importance of research in professional and personal development is increasingly being acknowledged. So why should children not benefit in a similar way? Traditionally, children have been excluded from this learning process because research methodology is considered too difficult for them. Principal obstacles focus around three key barriers:…

  12. Step by Step: Social Skills Instruction for Students with Autism Spectrum Disorder Using Video Models and Peer Mentors

    ERIC Educational Resources Information Center

    Ogilvie, Christine R.

    2011-01-01

    For children with autism spectrum disorder (ASD), impairments in social skills can impact interactions with peers, family members, and the world. Impairments in social skills vary from person to person, and may include lack of eye contact, limited affect, or nonexistent verbal communication. One strategy for teaching social skills to children with…

  13. Ceim ar Cheim, Step by Step--Community Music Programme in an Irish Probation Centre: A Personal Reflection

    ERIC Educational Resources Information Center

    Tiernan, Julie

    2010-01-01

    Proactive instruction and alternative education have progressively become the schooling of choice for many non-traditional learners in Ireland. Community training, probation and Traveller support centers endeavour to take an existing curriculum and tailor it to such learners' needs. One community based education and training centre funded by the…

  14. The Marginal Teacher: A Step-by-Step Guide to Fair Procedures for Identification and Dismissal. Second Edition.

    ERIC Educational Resources Information Center

    Lawrence, C. Edward; Vachon, Myra K.; Leake, Donald O.; Leake, Brenda H.

    This work provides sample letters, charts, timelines, and checklists, to help principals adequately prepare for possible teacher dismissal. Chapter 1, "Describing the Marginal Teacher," lists traits common to marginal teachers. Chapter 2, "Establishing the Teacher Evaluation Process," presents a monthly timeline for assessing…

  15. Surface functionalizing of a lipid nanosystem to promote brain targeting: step-by-step design and physico-chemical characterization.

    PubMed

    Cózar-Bernal, M J; García-Esteban, E; Sánchez-Soto, P J; Rabasco, A M; González-Rodríguez, M L

    2016-11-01

    The use of lipid nanosystems as drug delivery to the central nervous system may be advantageous over the current strategies. The aim of this study was to develop and characterize functionalized liposomes for treatment of brain diseases. The covalent method of coupling IgG to liposomes via the derivatized lipid 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidophenyl)butyramide](MPB-PE) was investigated. Optimized coupling conditions are shown to result in the efficient conjugation of IgG to liposomes containing low concentrations of MPB-PE (3/1 SH:IgG). The qualitative analysis has shown that after the extrusion process, more homogeneous populations of vesicles have been obtained with a nanometric size suitable to be effective to further anchor the protein. Negative values of zeta potential demonstrate that they are stable systems. Lyophilization was used to maintain the stability of the formulation. These very interesting results encourage further investigations to formulate peptide- and protein-loaded immunoliposomes, making targeting of liposomes as an attractive approach for brain drug delivery.

  16. "So We Adapt Step by Step": Acculturation experiences affecting diabetes management and perceived health for Chinese American immigrants.

    PubMed

    Chun, Kevin M; Chesla, Catherine A; Kwan, Christine M L

    2011-01-01

    This study examines how acculturation affects type 2 diabetes management and perceived health for Chinese American immigrants in the U.S. Acculturation experiences or cultural adaptation experiences affecting diabetes management and health were solicited from an informant group of immigrant patients and their spouses (N = 40) during group, couple and individual interviews conducted from 2005 to 2008. A separate respondent group of immigrant patients and their spouses (N = 19) meeting inclusion criteria reviewed and confirmed themes generated by the informant group. Using interpretive phenomenology, three key themes in patients' and spouses' acculturation experiences were identified: a) utilizing health care, b) maintaining family relations and roles, and c) establishing community ties and groundedness in the U.S. Acculturation experiences reflecting these themes were broad in scope and not fully captured by current self-report and proxy acculturation measures. In the current study, shifting family roles and evaluations of diabetes care and physical environment in the U.S. significantly affected diabetes management and health, yet are overlooked in acculturation and health investigations. Furthermore, the salience and impact of specific acculturation experiences respective to diabetes management and perceived health varied across participants due to individual, family, developmental, and environmental factors. In regards to salience, maintaining filial and interdependent family relations in the U.S. was of particular concern for older participants and coping with inadequate health insurance in the U.S. was especially distressing for self-described lower-middle to middle-class participants. In terms of impact, family separation and relocating to ethnically similar neighborhoods in the U.S. differentially affected diabetes management and health due to participants' varied family relations and pre-migration family support levels and diverse cultural and linguistic backgrounds, respectively. Implications for expanding current conceptualizations and measures of acculturation to better comprehend its dynamic and multidimensional properties and complex effects on health are discussed. Additionally, implications for developing culturally-appropriate diabetes management recommendations for Chinese immigrants and their families are outlined.

  17. Solar Workbook. A Step by Step Procedure for Assessing Solar Opportunities in Existing Buildings in New York State.

    ERIC Educational Resources Information Center

    New York State Energy Office, Albany.

    Determining the feasibility of modifying existing buildings to take advantage of solar energy requires a formal technical study. This workbook is designed to help the reader perform a preliminary analysis to decide whether investing in such a formal study would be beneficial. The book guides the user through an exploration of the general…

  18. A novel test of planning ability: great apes can plan step-by-step but not in advance of action.

    PubMed

    Tecwyn, Emma C; Thorpe, Susannah K S; Chappell, Jackie

    2013-11-01

    The ability to identify an appropriate sequence of actions or to consider alternative possible action sequences might be particularly useful during problem solving in the physical domain. We developed a new 'paddle-box' task to test the ability of different ape species to plan an appropriate sequence of physical actions (rotating paddles) to retrieve a reward from a goal location. The task had an adjustable difficulty level and was not dependent on species-specific behaviours (e.g. complex tool use). We investigated the planning abilities of captive orangutans (Pongo pygmaeus) and bonobos (Pan paniscus) using the paddle-box. In experiment 1, subjects had to rotate one or two paddles before rotating the paddle with the reward on. Subjects of both species performed poorly, though orangutans rotated more non-food paddles, which may be related to their greater exploratory tendencies and bolder temperament compared with bonobos. In experiment 2 subjects could always rotate the paddle with the reward on first and still succeed, and most subjects of both species performed appropriate sequences of up to three paddle rotations to retrieve the reward. Poor performance in experiment 1 may have been related to subjects' difficulty in inhibiting the prepotent response to act on the reward immediately.

  19. Every Nursery Needs a Garden: A Step-by-Step Guide to Creating and Using a Garden with Young Children

    ERIC Educational Resources Information Center

    Watts, Ann

    2011-01-01

    A garden can be a magical place for young children and offers them rich and engaging learning experiences as they interact with a variety of plants and wildlife throughout the year. This book guides you through the process of creating a garden, however small, for young children. It looks at the impact a garden area can have on children's overall…

  20. Tools for Transition in Early Childhood: A Step-by-Step Guide for Agencies, Teachers, and Families

    ERIC Educational Resources Information Center

    Rous, Beth S., Ed.D; Hallam, Rena A.

    2006-01-01

    For young children with and without disabilities, positive outcomes depend on smooth, effective transitions between and within early intervention programs, preschool programs, and public school programs. Now there is a how-to guide that helps professionals across programs work together to make these transitions happen. Coauthored by top expert…

  1. Fermentation guide for common grains: a step-by-step procedure for small-scale ethanol fuel production

    SciTech Connect

    Not Available

    1981-06-01

    This booklet covers in detail all the procedures prior to and including fermentation that are necessary to produce the highest possible yields from small-scale ethanol plants. Batch starch conversion of corn, barley, wheat, and milo using enzymes (..cap alpha..-amylase and glucoamylase) from bacteria and fungi is described. The types of yeast to use in fermenting the mash and the equipment and chemicals needed are detailed. Refinements that can help to improve ethanol production are presented. (DMC)

  2. Rolled knitted scaffolds based on PLA-pluronic copolymers for anterior cruciate ligament reinforcement: A step by step conception.

    PubMed

    Pinese, Coline; Leroy, Adrien; Nottelet, Benjamin; Gagnieu, Christian; Coudane, Jean; Garric, Xavier

    2016-01-05

    The aim of this study was to prepare a new knitted scaffold from PLA-Pluronic block copolymers for anterior cruciate ligament reconstruction. The impact of sterilization methods (beta-ray and gamma-ray sterilization) on copolymers was first evaluated in order to take into account the possible damages due to the sterilization process. Beta-ray radiation did not significantly change mechanical properties in contrast to gamma-ray sterilization. It was shown that ACL cells proliferate onto these copolymers, demonstrating their cytocompatibility. Thirdly, in order to study the influence of shaping on mechanical properties, several shapes were created with copolymers yarns: braids, ropes and linear or rolled knitted scaffolds. The rolled knitted scaffold presented interesting mechanical characteristics, similar to native anterior cruciate ligament (ACL) with a 67 MPa Young's Modulus and a stress at failure of 22.5 MPa. These findings suggest that this three dimensional rolled knitted scaffold meet the mechanical properties of ligament tissues and could be suitable as a scaffold for ligament reconstruction. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2016.

  3. [Why and how to perform an ultrasound-guided transversus abdominis plane block: A step-by-step approach].

    PubMed

    Nohuz, E; El Drayi, B; Triki, A; Grossmannova, K; Boudier, B; Koffi, K; Albaut, M; Dualé, C

    2016-12-01

    Used in clinical practice as part of a multimodal analgesic regimen, the transversus abdominis plane block (TAP block) is a relative novel procedure in which local anaesthetic agents are injected into the anatomic neurofascial space between the internal oblique and the transversus abdominis muscle. It allows a significantly prolonged duration of analgesia during the early postoperative stage in abdominal surgery. This regional anesthesia technique provides analgesia to the skin, muscles of the anterior abdominal wall and parietal peritoneum in order to decrease the incision-related pain. Thus, it reduces postoperative opiate requirements and opioids-related side effects (nausea, vomiting, delayed resumption of intestinal transit, drowsiness, respiratory depression, urine retention). Additionally, the TAP block appears particularly interesting when neuraxial techniques or opioids are contraindicated. Moreover, the ultrasound-guided procedure provides a significant success rate of this block and additionally avoids major complications. We describe our technique of ultrasound-guided TAP block and discuss its indications, contraindication and potential complications.

  4. Step-by-Step Simulation of Radiation of Radiation Chemistry Using Green Functions for Diffusion-Influenced Reactions

    NASA Technical Reports Server (NTRS)

    Plante, Ianik; Cucinotta, Francis A.

    2011-01-01

    The irradiation of biological systems leads to the formation of radiolytic species such as H(raised dot), (raised dot)OH, H2, H2O2, e(sup -)(sub aq), etc.[1]. These species react with neighboring molecules, which result in damage in biological molecules such as DNA. Radiation chemistry is there for every important to understand the radiobiological consequences of radiation[2]. In this work, we discuss an approach based on the exact Green Functions for diffusion-influenced reactions which may be used to simulate radiation chemistry and eventually extended to study more complex systems, including DNA.

  5. The relationship between the lizard eye and associated bony features: a cautionary note for interpreting fossil activity patterns.

    PubMed

    Hall, Margaret I

    2009-06-01

    Activity pattern, the time of day when an animal is active, is associated with ecology. There are two major activity patterns: diurnal (awake during the day in a photopic environment) and nocturnal (awake at night in a scotopic environment). Lizards exhibit characteristic eye shapes associated with activity pattern, with scotopic-adapted lizard eyes optimized for visual sensitivity with large corneal diameters relative to their eye axial lengths, and photopic-adapted lizards optimized for visual acuity, with larger axial lengths of the eye relative to their corneal diameters. This study: (1) quantifies the relationship between the lizard eye and its associated bony anatomy (the orbit, sclerotic ring, and associated skull widths); (2) investigates how activity pattern is reflected in that bony anatomy; and (3) determines if it is possible to reliably interpret activity pattern for a lizard that does not have the soft tissue available for study, specifically, for a fossil. Knowledge of extinct lizards' activity patterns would be useful in making paleoecological interpretations. Here, 96 scotopic- and photopic-adapted lizard species are analyzed in a phylogenetic context. Although there is a close relationship between the lepidosaur eye and associated bony anatomy, based on these data activity pattern cannot be reliably interpreted for bony-only specimens, such as a fossil, possibly because of the limited ossification of the lepidosaur skull. Caution should be exercised when utilizing lizard bony anatomy to interpret light-level adaptation, either for a fossil lizard or as part of an extant phylogenetic bracket to interpret other extinct animals with sclerotic rings, such as dinosaurs.

  6. Technical note: Evaluation of an ear-attached movement sensor to record cow feeding behavior and activity.

    PubMed

    Bikker, J P; van Laar, H; Rump, P; Doorenbos, J; van Meurs, K; Griffioen, G M; Dijkstra, J

    2014-05-01

    The ability to monitor dairy cow feeding behavior and activity could improve dairy herd management. A 3-dimensional accelerometer (SensOor; Agis Automatisering BV, Harmelen, the Netherlands) has been developed that can be attached to ear identification tags. Based on the principle that behavior can be identified by ear movements, a proprietary model classifies sensor data as "ruminating," "eating," "resting," or "active." The objective of the study was to evaluate this sensor on accuracy and precision. First, a pilot evaluation of agreement between 2 independent observers, recording behavior from 3 cows for a period of approximately 9h each, was performed. Second, to evaluate the sensor, the behavior of 15 cows was monitored both visually (VIS) and with the sensor (SENS), with approximately 20 h of registration per cow, evenly distributed over a 24-h period, excluding milking. Cows were chosen from groups of animals in different lactation stages and parities. Each minute of SENS and VIS data was classified into 1 of 9 categories (8 behaviors and 1 transition behavior) and summarized into 4 behavioral groups, namely ruminating, eating, resting, or active, which were analyzed by calculating kappa (κ) values. For the pilot evaluation, a high level of agreement between observers was obtained, with κ values of ≥ 0.96 for all behavioral categories, indicating that visual observation provides a good standard. For the second trial, relationships between SENS and VIS were studied by κ values on a minute basis and Pearson correlation and concordance correlation coefficient analysis on behavior expressed as percentage of total registration time. Times spent ruminating, eating, resting, and active were 42.6, 15.9, 31.6, and 9.9% (SENS) respectively, and 42.1, 13.0, 30.0, and 14.9% (VIS), respectively. Overall κ for the comparison of SENS and VIS was substantial (0.78), with κ values of 0.85, 0.77, 0.86, and 0.47 for "ruminating," "eating," "resting," and "active

  7. Technical note: Validation of a commercial system for the continuous and automated monitoring of dairy cow activity.

    PubMed

    Tullo, E; Fontana, I; Gottardo, D; Sloth, K H; Guarino, M

    2016-09-01

    Current farm sizes do not allow the precise identification and tracking of individual cows and their health and behavioral records. Currently, the application of information technology within intensive dairy farming takes a key role in proper routine management to improve animal welfare and to enhance the comfort of dairy cows. An existing application based on information technology is represented by the GEA CowView system (GEA Farm Technologies, Bönen, Germany). This system is able to detect and monitor animal behavioral activities based on positioning, through the creation of a virtual map of the barn that outlines all the areas where cows have access. The aim of this study was to validate the accuracy, sensitivity, and specificity of data provided by the CowView system. The validation was performed by comparing data automatically obtained from the CowView system with those obtained by a manual labeling procedure performed on video recordings. Data used for the comparisons were represented by the zone-related activities performed by the selected dairy cows and were classified into 2 categories: activity and localization. The duration in seconds of each of the activities/localizations detected both with the manual labeling and with the automated system were used to evaluate the correlation coefficients among data; and subsequently the accuracy, sensitivity, specificity, and positive and negative predictive values of the automated monitoring system were calculated. The results of this validation study showed that the CowView automated monitoring system is able to identify the cow localization/position (alley, trough, cubicles) with high reliability in relation to the zone-related activities performed by dairy cows (accuracy higher than 95%). The results obtained support the CowView system as an innovative potential solution for the easier management of dairy cows.

  8. Note: Fully integrated active quenching circuit achieving 100 MHz count rate with custom technology single photon avalanche diodes.

    PubMed

    Acconcia, G; Labanca, I; Rech, I; Gulinatti, A; Ghioni, M

    2017-02-01

    The minimization of Single Photon Avalanche Diodes (SPADs) dead time is a key factor to speed up photon counting and timing measurements. We present a fully integrated Active Quenching Circuit (AQC) able to provide a count rate as high as 100 MHz with custom technology SPAD detectors. The AQC can also operate the new red enhanced SPAD and provide the timing information with a timing jitter Full Width at Half Maximum (FWHM) as low as 160 ps.

  9. Note: Fully integrated active quenching circuit achieving 100 MHz count rate with custom technology single photon avalanche diodes

    NASA Astrophysics Data System (ADS)

    Acconcia, G.; Labanca, I.; Rech, I.; Gulinatti, A.; Ghioni, M.

    2017-02-01

    The minimization of Single Photon Avalanche Diodes (SPADs) dead time is a key factor to speed up photon counting and timing measurements. We present a fully integrated Active Quenching Circuit (AQC) able to provide a count rate as high as 100 MHz with custom technology SPAD detectors. The AQC can also operate the new red enhanced SPAD and provide the timing information with a timing jitter Full Width at Half Maximum (FWHM) as low as 160 ps.

  10. BASINS Technical Notes

    EPA Pesticide Factsheets

    EPA has developed several technical notes that provide in depth information on a specific function in BASINS. Technical notes can be used to answer questions users may have, or to provide additional information on the application of features in BASINS.

  11. Evaluation of sample preparation methods for water activity determination in jerky and kippered beef: a research note.

    PubMed

    Harper, N M; Getty, K J K; Boyle, E A E

    2010-10-01

    Commercially available packaged whole muscle beef jerky, chopped and formed beef jerky, and kippered beef steak were obtained from retail stores to determine the effect of two sample preparation methods on water activity (a(w)). Intact samples were prepared by cutting product into a hexagonal shape with a 3.2 cm diameter. Diced samples were prepared by cutting the product into 0.4 x 0.4 cm squares. Whole muscle jerky a(w) was higher (0.016 units; P<0.001) using the intact method compared to the diced method. There was no difference (P>0.05) in a(w) levels between the two preparation methods for chopped and formed jerky or kippered beef steak. An intact sample preparation method is recommended for a(w) determination of whole muscle jerky to obtain a more conservative value, especially if a(w) is near the margin of safety.

  12. Making an Adjustable C-Clamp. Kit No. 603. Instructor's Manual [and] Student Learning Activity Manual. [Revised.] T & I--Metalwork.

    ERIC Educational Resources Information Center

    White, Jim; Alexander, Larry

    This student activity kit consists of a programmed, self-instructional learning guide and an accompanying instructor's manual for use in teaching trade and industrial education students how to make an adjustable C-clamp. The student guide contains step-by-step instructions in the following areas: basic layout principles; use of a hack saw, file,…

  13. A note on the effect of the full moon on the activity of wild maned wolves, Chrysocyon brachyurus.

    PubMed

    Sábato, Marco Aurélio Lima; de Melo, Luiz Fernando Bandeira; Magni, Elisa M Vaz; Young, Robert John; Coelho, Carlyle Mendes

    2006-09-01

    It is well established in the scientific literature that animal prey species reduce their activity at times of high predation risk. In the case of nocturnal animals this occurs when there is a full moon; however, the response of predators to the changes in their prey behaviour is relatively unknown. Two responses are possible: (1) increase in search effort to maintain food intake; or (2) decrease in distance travelled due to either: (a) an effort to conserve energy or (b) increased kill efficiency. Using GPS tracking collars we monitored the distances travelled (which is representative of search effort) by three maned wolves during the night of the full and new moon for five lunar cycles (during the dry season). A Wilcoxon matched-paired test showed that the maned wolves travelled significantly less during the full compared to the new moon (p < 0.05). On average, during the 10 h of darkness during a full moon maned wolves travelled 1.88 km less than on a new moon. These data suggest that maned wolves respond to temporally reduced prey availability by reducing their distance travelled.

  14. The Research Assessment Exercise and Motivation: A Note on the Difference in the Impact on the Active Researchers and the Non-Active.

    ERIC Educational Resources Information Center

    Talib, Ameen Ali

    2002-01-01

    Surveyed British academics, hypothesizing that the effect of Britain's Research Assessment Exercise (RAE) on individual academics is dependent on their self-assessed level of research activity. Found that the RAE's effect does appear to be dependent on level of research activity, with moderately active researchers the most influenced to increase…

  15. A note on notes: note taking and containment.

    PubMed

    Levine, Howard B

    2007-07-01

    In extreme situations of massive projective identification, both the analyst and the patient may come to share a fantasy or belief that his or her own psychic reality will be annihilated if the psychic reality of the other is accepted or adopted (Britton 1998). In the example of' Dr. M and his patient, the paradoxical dilemma around note taking had highly specific transference meanings; it was not simply an instance of the generalized human response of distracted attention that Freud (1912) had spoken of, nor was it the destabilization of analytic functioning that I tried to describe in my work with Mr. L. Whether such meanings will always exist in these situations remains a matter to be determined by further clinical experience. In reopening a dialogue about note taking during sessions, I have attempted to move the discussion away from categorical injunctions about what analysis should or should not do, and instead to foster a more nuanced, dynamic, and pair-specific consideration of the analyst's functioning in the immediate context of the analytic relationship. There is, of course, a wide variety of listening styles among analysts, and each analyst's mental functioning may be affected differently by each patient whom the analyst sees. I have raised many questions in the hopes of stimulating an expanded discussion that will allow us to share our experiences and perhaps reach additional conclusions. Further consideration may lead us to decide whether note taking may have very different meanings for other analysts and analyst-patient pairs, and whether it may serve useful functions in addition to the one that I have described.

  16. Sticky-Note Murals

    ERIC Educational Resources Information Center

    Sands, Ian

    2011-01-01

    In this article, the author describes a sticky-note mural project that originated from his desire to incorporate contemporary materials into his assignments as well as to inspire collaboration between students. The process takes much more than sticking sticky notes to the wall. It takes critical thinking skills and teamwork to design and complete…

  17. LUVOIR Tech Notes

    NASA Technical Reports Server (NTRS)

    Bolcar, Matthew R.; Shaklan, Stuart; Roberge, Aki; Rioux, Norman; Feinberg, Lee; Werner, Michael; Rauscher, Bernard; Mandell, Avi; France, Kevin; Schiminovich, David

    2016-01-01

    We present nine "tech notes" prepared by the Large UV/Optical/Infrared (LUVOIR) Science and Technology Definition Team (STDT), Study Office, and Technology Working Group. These tech notes are intended to highlight technical challenges that represent boundaries in the trade space for developing the LUVOIR architecture that may impact the science objectives being developed by the STDT. These tech notes are intended to be high-level discussions of the technical challenges and will serve as starting points for more in-depth analysis as the LUVOIR study progresses.

  18. Notes on Piezoelectricity

    SciTech Connect

    Redondo, Antonio

    2016-02-03

    These notes provide a pedagogical discussion of the physics of piezoelectricity. The exposition starts with a brief analysis of the classical (continuum) theory of piezoelectric phenomena in solids. The main subject of the notes is, however, a quantum mechanical analysis. We first derive the Frohlich Hamiltonian as part of the description of the electron-phonon interaction. The results of this analysis are then employed to derive the equations of piezoelectricity. A couple of examples with the zinc blende and and wurtzite structures are presented at the end

  19. Robotics Technical Note 102.

    DTIC Science & Technology

    1981-06-01

    IAfl-AIBZ 4U2 AIR FORCE BUSINESS RESEARCH MANAGEMENT CENTER WRIGHT-ETC F/6 13/8 I ROBOTICS TECHNIICAL NOTE 102.(U) JUN Al B M BLABIERSALL UNCLASSIFE...CATALOG uME 1T4.T7- Subtitle S. TYPE OF REPOR & PERIOO COVERED Technical Note 102 Robotics 𔄁 FInal r ---- 6. PERFORMING O1G. REPORT NUMBER C 7. A tNORa B...Identify by block number) Robotics Manufacturing Industrial Robots Robot Technology SRobotics Application BQ~.STRACT (Continue on revere* side It

  20. Notes and Discussion

    ERIC Educational Resources Information Center

    American Journal of Physics, 1978

    1978-01-01

    Includes eleven short notes, comments and responses to comments on a variety of topics such as uncertainty in a least-squares fit, display of diffraction patterns, the dark night sky paradox, error in the dynamics of deformable bodies and relative velocities and the runner. (GA)

  1. Notes on Linguistics, 1990.

    ERIC Educational Resources Information Center

    Notes on Linguistics, 1990

    1990-01-01

    This document consists of the four issues of "Notes on Linguistics" published during 1990. Articles in the four issues include: "The Indians Do Say Ugh-Ugh" (Howard W. Law); "Constraints of Relevance, A Key to Particle Typology" (Regina Blass); "Whatever Happened to Me? (An Objective Case Study)" (Aretta…

  2. Notes on Linguistics, 1999.

    ERIC Educational Resources Information Center

    Payne, David, Ed.

    1999-01-01

    The 1999 issues of "Notes on Linguistics," published quarterly, include the following articles, review articles, reviews, book notices, and reports: "A New Program for Doing Morphology: Hermit Crab"; "Lingualinks CD-ROM: Field Guide to Recording Language Data"; "'Unruly' Phonology: An Introduction to Optimality Theory"; "Borrowing vs. Code…

  3. Sawtooth Functions. Classroom Notes

    ERIC Educational Resources Information Center

    Hirst, Keith

    2004-01-01

    Using MAPLE enables students to consider many examples which would be very tedious to work out by hand. This applies to graph plotting as well as to algebraic manipulation. The challenge is to use these observations to develop the students' understanding of mathematical concepts. In this note an interesting relationship arising from inverse…

  4. Programmable Logic Application Notes

    NASA Technical Reports Server (NTRS)

    Katz, Richard

    2000-01-01

    This column will be provided each quarter as a source for reliability, radiation results, NASA capabilities, and other information on programmable logic devices and related applications. This quarter will start a series of notes concentrating on analysis techniques with this issues section discussing worst-case analysis requirements.

  5. Programmable Logic Application Notes

    NASA Technical Reports Server (NTRS)

    Katz, Richard; Day, John H. (Technical Monitor)

    2001-01-01

    This report will be provided each quarter as a source for reliability, radiation results, NASA capabilities, and other information on programmable logic devices and related applications. This quarter will continue a series of notes concentrating on analysis techniques with this issue's section discussing the use of Root-Sum-Square calculations for digital delays.

  6. 4. Panama Mount. Note concrete ring and metal rail. Note ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Panama Mount. Note concrete ring and metal rail. Note cliff erosion under foundation at left center. Looking 297° W. - Fort Funston, Panama Mounts for 155mm Guns, Skyline Boulevard & Great Highway, San Francisco, San Francisco County, CA

  7. Note-Taking: Different Notes for Different Research Stages.

    ERIC Educational Resources Information Center

    Callison, Daniel

    2003-01-01

    Explains the need to teach students different strategies for taking notes for research, especially at the exploration and collecting information stages, based on Carol Kuhlthau's research process. Discusses format changes; using index cards; notes for live presentations or media presentations versus notes for printed sources; and forming focus…

  8. Elementary and Secondary Educational Services of Public Television Grantees: Highlights from the 1997 Station Activities Survey. CPB Research Notes, No. 104.

    ERIC Educational Resources Information Center

    Corporation for Public Broadcasting, Washington, DC.

    This report provides a summary of K-12 educational services offered by Corporation for Public Broadcasting-supported television stations from CPB's annual Station Activities Survey. Stations are broken into cohorts by license type and budget size. The 1997 Station Activities Survey asked public television stations whether they provided…

  9. Note: Magnetic targeting for enhancement of the activation efficiency of G protein-coupled receptor with a two-pair coil system.

    PubMed

    Cao, Quanliang; Han, Xiaotao; Chun, Lei; Liu, Jianfeng; Li, Liang

    2016-01-01

    Insufficient contact of drug with target cells is a primary reason for limited efficiency of G protein-coupled receptor activation. To overcome this limitation, a simple approach based on magnetic targeting for enhancing drug delivery towards the cell surfaces using magnetic nanoparticles and a two-pair coil system consisting of Helmholtz and Maxwell coils was reported. As a proof of the concept, comparative experiments on G protein-coupled receptor activation process were carried out and results show that the efficiency of G protein-coupled receptor activation can be increased about 6 times in the experiments with the aid of the proposed magnetic targeting system.

  10. What's In a Note: Construction of a Suicide Note Corpus.

    PubMed

    Pestian, John P; Matykiewicz, Pawel; Linn-Gust, Michelle

    2012-01-01

    This paper reports on the results of an initiative to create and annotate a corpus of suicide notes that can be used for machine learning. Ultimately, the corpus included 1,278 notes that were written by someone who died by suicide. Each note was reviewed by at least three annotators who mapped words or sentences to a schema of emotions. This corpus has already been used for extensive scientific research.

  11. Introducing ultrasound-guided vein catheterization into clinical practice: A step-by-step guide for organizing a hands-on training program with inexpensive handmade models

    PubMed Central

    Di Domenico, S.; Licausi, M.; Porcile, E.; Piaggio, F.; Troilo, B.; Centanaro, M.; Valente, U.

    2008-01-01

    Introduction Central vein catheterization (CVC) plays a central role in hospital patient management. Compared with the use of traditional anatomical landmarks, ultrasound-guidance is associated with higher CVC success rates, fewer complications, and more rapid central venous access. The use of US-guided CVC in clinical practice has not become widespread, largely because anesthesiology and general surgery residents receive limited training in this technique. To increase the use of US-guided CVC in our surgical department, we organized a hands-on training program based on the use of handmade models. Methods Three different models were constructed using plastic food-storage containers, segments of rubber tourniquet and silastic tubing (to simulate vessels), and agar gelatin. Results The hands-on training course allowed progressive acquisition of the basic hand–eye coordination skills necessary for performing US-guided venipuncture. The overall cost for each model was less than €5.00. Discussion The models described in this report are useful tools for teaching US-guided CVC. Thanks to their low-cost, they can be widely used to facilitate the introduction of this technique in clinical practice. PMID:23396222

  12. [Takotsubo and surroundings. Step by step postpartum stress-induced cardiomyopathy shows its facet. A peculiar case of atypical takotasubo in the peripartum period].

    PubMed

    Russo, Marco; Sappa, Roberta; Gianfagna, Enrico; Salame, Kareem; Sinagra, Gianfranco; Proclemer, Alessandro

    2014-01-01

    Takotsubo syndrome is an acquired cardiomyopathy with transient and reversible left ventricular dysfunction that can mimic an acute coronary syndrome. It is characterized by ECG abnormalities, including minimal ST-segment elevation and T-wave changes, mild troponin elevation, typical left ventricular regional wall motion abnormalities (apical ballooning) and atypical forms (midventricular or reverse apical ballooning) without significant coronary artery stenosis. Its etiology and pathophysiology remain unclear. The sympathetic system seems to play a central role: its exaggerated response to emotional or physical stress triggers may induce microvascular dysfunction and catecholamine-induced cardiotoxicity due to cyclic AMP-mediated calcium overload. We report our experience highlighting the possible pathophysiological and clinical overlap of emotional-triggered catecholamine cardiotoxicity, arterial hypertension and physiological cardiovascular overload in pregnancy describing an atypical case of takotsubo cardiomyopathy with diffuse left ventricular hypokinesia at onset and subsequent evolution to apical ballooning.

  13. Application of a snare technique in retrograde chronic total occlusion percutaneous coronary intervention – a step by step practical approach and an observational study

    PubMed Central

    Fang, Hsiu-Yu; Lee, Wei-Chieh; Fang, Chih-Yuan; Wu, Chiung-Jen

    2016-01-01

    Abstract Percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) has recently become popular among interventional cardiologists. CTO originating from the ostium has been one of the most difficult CTO lesions to treat with PCI for a number of reasons. Our aim was to illustrate a specific technique during retrograde CTO PCI referred to as the “snare technique.” We retrospectively examined the use of “snare technique” among 371 consecutive retrograde CTO PCIs performed at our institution between 2006 and 2015. “Snare technique” was used in 10 patients among the 371 retrograde CTO PCIs. The baseline clinical and angiographic characteristics of patients with or without “snare technique” were similar. The “snare technique” group had significantly fewer side branches at occlusion (30.0% vs 71.2%, P = 0.01) and a higher incidence of externalization (90% vs 25.5%, P < 0.001). The contrast volume was significantly lower in the “snare technique” group (285.0 ± 68.5 vs 379.2 ± 144.0, P = 0.04). The incidence of major complications, retrograde success, or final success did not differ between the groups. The “snare technique” is safe and feasible in retrograde CTO PCI, especially in cases of difficult coronary engagement in cases such as ostial occlusion, challenging coronary anatomy, or retrograde guidewire cannot get in antegrade guiding catheter. PMID:27741138

  14. Snuggle T and protrusion (S-TAP) technique for coronary bifurcation stenting: A step-by-step angiographic and illustration demonstration.

    PubMed

    Dahdouh, Ziad; Fadel, Bahaa M; Roule, Vincent; Sarkis, Antoine; Grollier, Gilles

    2017-02-08

    T and small protrusion (TAP) is a stenting technique that is utilized for the management of coronary bifurcation lesions when using a two-stent strategy. This technique is also useful whenever stenting of a main vessel (MV) jeopardizes a side branch (SB) or when a sub-optimal result is encountered in a daughter vessel after starting with one-stent approach. The conversion from one-stent strategy to TAP could be achieved smoothly and often leads to good results. Technically, optimal positioning of the SB stent to achieve the required protrusion into the lumen of the MV remains a challenge. Toward that goal we propose an added step that involves inflating a balloon in the MV to serve as an anvil with simultaneous pullback of the SB stent, to be followed by stent deployment. We refer to this approach as the snuggle T and protrusion (S-TAP) technique owing to close contact between the SB stent and the MV balloon during simultaneous inflation. In this manuscript, we detail this interventional technique and provide a demonstrative case study.

  15. Non Linear Step By Step Seismic Response and the Push Over Analysis Comparison of a Reinforced Concrete of Ductile Frames 25 Level Building

    SciTech Connect

    Avila, Jorge A.; Martinez, Eduardo

    2008-07-08

    Based on a ductile frames 25 level building, a non-linear analysis with increased monotonically lateral loads (Push-Over) was made in order to determine its collapse and its principal responses were compared against the time-history seismic responses determined with the SCT-EW-85 record. The seismic-resistance design and faced to gravitational loads was made according to the Complementary Technical Norms of Concrete Structures Design (NTC-Concrete) and the NTC-Seismic of the Mexico City Code (RDF-04), satisfying the limit service states (relative lateral displacement between story height maximum relations, story drifts {<=}0.012) and failure (seismic behavior factor, Q = 3). The compressible (soft) seismic zone III{sub b} and the office use type (group B) were considered. The non-lineal responses were determined with nominal and over-resistance effects. The comparison were made with base shear force-roof lateral displacement relations, global distribution of plastic hinges, failure mechanics tendency, lateral displacements and story drift and its distribution along the height of the building, local and global ductility demands, etc. For the non-linear static analysis with increased monotonically lateral loads, was important to select the type of lateral forces distribution.

  16. Deconstructing Chronic Low Back Pain in the Older Adult – Step by Step Evidence and Expert-Based Recommendations for Evaluation and Treatment: Part III: Fibromyalgia Syndrome

    PubMed Central

    Fatemi, Gita; Fang, Meika A.; Breuer, Paula; Cherniak, Paul E.; Gentili, Angela; Hanlon, Joseph T.; Karp, Jordan F.; Morone, Natalia E.; Rodriguez, Eric; Rossi, Michelle I.; Schmader, Kenneth; Weiner, Debra K.

    2016-01-01

    Objective To present the third in a series of articles designed to deconstruct chronic low back pain (CLBP) in older adults. The series presents CLBP as a syndrome, a final common pathway for the expression of multiple contributors rather than a disease localized exclusively to the lumbosacral spine. Each article addresses one of twelve important contributors to pain and disability in older adults with CLBP. This article focuses on fibromyalgia syndrome (FMS). Methods A modified Delphi approach was used to create the evaluation and treatment algorithm, the table discussing the rationale behind each of the algorithm components, and the stepped-care drug recommendations. The team involved in the creation of these materials consisted of a principal investigator, a 5-member content expert panel, and a 9-member primary care panel. The evaluation and treatment recommendations were based on availability of medications and other resources within the Veterans Health Administration (VHA) facilities. However, non-VHA panelists were also involved in the development of these materials, which can be applied to both VA and civilian settings. The illustrative clinical case was taken from the clinical practice of the principal investigator. Results Following expert consultations and a review of the literature, we developed an evaluation and treatment algorithm with supporting materials to aid in the care of older adults with CLBP who have concomitant FMS. A case is presented that demonstrates the complexity of pain evaluation and management in older patients with CLBP and concomitant FMS Conclusions Recognition of FMS as a common contributor to CLBP in older adults and initiating treatment targeting both FMS and CLBP will lead to improved outcomes in pain and disability. PMID:26272644

  17. Deconstructing Chronic Low Back Pain in the Older Adult-Step by Step Evidence and Expert-Based Recommendations for Evaluation and Treatment: Part VII: Insomnia.

    PubMed

    Bramoweth, Adam D; Renqvist, Jenna G; Germain, Anne; Buysse, Daniel J; Gentili, Angela; Kochersberger, Gary; Rodriguez, Eric; Rossi, Michelle I; Weiner, Debra K

    2016-05-01

    OBJECTIVE : To present the seventh in a series of articles designed to deconstruct chronic low back pain (CLBP) in older adults. This article focuses on insomnia and presents a treatment algorithm for managing insomnia in older adults, along with a representative clinical case. METHODS : A modified Delphi process was used to develop the algorithm and supportive materials. A multidisciplinary expert panel representing expertise in health psychology and sleep medicine developed the algorithm and supporting documents that were subsequently refined through an iterative process of input from a primary care provider panel. RESULTS : We present an illustrative clinical case and an algorithm to help guide the care of older adults with insomnia, an important contributor to CLBP and disability. Multicomponent cognitive behavioral therapy for insomnia (CBTI) and similar treatments (e.g., brief behavioral treatment for insomnia [BBTI]) are the recommended first-line treatment. Medications should be considered only if BBTI/CBTI is suboptimal or not effective and should be prescribed at the lowest effective dose for short periods of time (< 90 days). CONCLUSIONS : Insomnia is commonly comorbid with CLBP in older adults and should be routinely evaluated and treated because it is an important contributor to pain and disability. The algorithm presented was structured to assist primary care providers in planning treatment for older adults with CLBP and insomnia.

  18. Application of a snare technique in retrograde chronic total occlusion percutaneous coronary intervention - a step by step practical approach and an observational study.

    PubMed

    Fang, Hsiu-Yu; Lee, Wei-Chieh; Fang, Chih-Yuan; Wu, Chiung-Jen

    2016-10-01

    Percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) has recently become popular among interventional cardiologists. CTO originating from the ostium has been one of the most difficult CTO lesions to treat with PCI for a number of reasons. Our aim was to illustrate a specific technique during retrograde CTO PCI referred to as the "snare technique."We retrospectively examined the use of "snare technique" among 371 consecutive retrograde CTO PCIs performed at our institution between 2006 and 2015."Snare technique" was used in 10 patients among the 371 retrograde CTO PCIs. The baseline clinical and angiographic characteristics of patients with or without "snare technique" were similar. The "snare technique" group had significantly fewer side branches at occlusion (30.0% vs 71.2%, P = 0.01) and a higher incidence of externalization (90% vs 25.5%, P < 0.001). The contrast volume was significantly lower in the "snare technique" group (285.0 ± 68.5 vs 379.2 ± 144.0, P = 0.04). The incidence of major complications, retrograde success, or final success did not differ between the groups.The "snare technique" is safe and feasible in retrograde CTO PCI, especially in cases of difficult coronary engagement in cases such as ostial occlusion, challenging coronary anatomy, or retrograde guidewire cannot get in antegrade guiding catheter.

  19. A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor.

    PubMed

    Lun, Aaron T L; McCarthy, Davis J; Marioni, John C

    2016-01-01

    Single-cell RNA sequencing (scRNA-seq) is widely used to profile the transcriptome of individual cells. This provides biological resolution that cannot be matched by bulk RNA sequencing, at the cost of increased technical noise and data complexity. The differences between scRNA-seq and bulk RNA-seq data mean that the analysis of the former cannot be performed by recycling bioinformatics pipelines for the latter. Rather, dedicated single-cell methods are required at various steps to exploit the cellular resolution while accounting for technical noise. This article describes a computational workflow for low-level analyses of scRNA-seq data, based primarily on software packages from the open-source Bioconductor project. It covers basic steps including quality control, data exploration and normalization, as well as more complex procedures such as cell cycle phase assignment, identification of highly variable and correlated genes, clustering into subpopulations and marker gene detection. Analyses were demonstrated on gene-level count data from several publicly available datasets involving haematopoietic stem cells, brain-derived cells, T-helper cells and mouse embryonic stem cells. This will provide a range of usage scenarios from which readers can construct their own analysis pipelines.

  20. Deconstructing Chronic Low Back Pain in the Older Adult: Step by Step Evidence and Expert-Based Recommendations for Evaluation and Treatment

    PubMed Central

    Carley, Joseph A.; Karp, Jordan F.; Gentili, Angela; Marcum, Zachary A.; Reid, M. Carrington; Rodriguez, Eric; Rossi, Michelle I.; Shega, Joseph; Thielke, Stephen; Weiner, Debra K.

    2016-01-01

    Objective To present the fourth in a series of articles designed to deconstruct chronic low back pain (CLBP) in older adults. The series presents CLBP as a syndrome, a final common pathway for the expression of multiple contributors rather than a disease localized exclusively to the lumbosacral spine. Each article addresses one of twelve important contributors to pain and disability in older adults with CLBP. This article focuses on depression. Methods The evaluation and treatment algorithm, a table articulating the rationale for the individual algorithm components, and stepped-care drug recommendations were developed using a modified Delphi approach. The Principal Investigator, a three-member content expert panel, and a nine-member primary care panel were involved in the iterative development of these materials. The algorithm was developed keeping in mind medications and other resources available within Veterans Health Administration (VHA) facilities. As panelists were not exclusive to the VHA, the materials can be applied in both VHA and civilian settings. The illustrative clinical case was taken from one of the contributor’s clinical practice. Results We present an algorithm and supportive materials to help guide the care of older adults with depression, an important contributor to CLBP. The case illustrates an example of a complex clinical presentation in which depression was an important contributor to symptoms and disability in an older adult with CLBP. Conclusions Depression is common and should be evaluated routinely in the older adult with CLBP so that appropriately targeted treatments can be planned and implemented. PMID:26539754

  1. An inexpensive, charge-balanced rodent deep brain stimulation device: a step-by-step guide to its procurement and construction

    PubMed Central

    Ewing, Samuel G.; Lipski, Witold J.; Grace, Anthony A.; Winter, Christine

    2013-01-01

    Background Despite there being a relatively large number of methods papers which detail specifically the development of stimulation devices, only a small number of reports involve the application of these devices in freely moving animals. To date multiple preclinical neural stimulators have been designed and described but have failed to make an impact on the methods employed by the majority of laboratories studying DBS. Thus, the overwhelming majority of DBS studies are still performed by tethering the subject to an external stimulator. We believe that the low adoption rate of previously described methods is a result of the complexity of replicating and implementing these methods. New Method Here were describe both the design and procurement of a simple and inexpensive stimulator designed to be compatible with commonly used, commercially available electrodes (Plastics 1). Results This system is initially programmable in frequency, pulsewidth and current amplitude, and delivers biphasic, charge-balanced output to two independent electrodes. Comparison with Existing Method(s) It is easy to implement requiring neither subcutaneous implantation or custom-made electrodes and has been optimized for either direct mounting to the head or for use with rodent jackets. Conclusions This device is inexpensive and universally accessible, facilitating high throughput, low cost, long-term rodent deep brain stimulation experiments. PMID:23954265

  2. The Elements of an Effective Dissertation and Thesis: A Step-by-Step Guide to Getting it Right the First Time

    ERIC Educational Resources Information Center

    Calabrese, Raymond L.

    2006-01-01

    This is a student guide to writing an effective doctoral dissertation or a master's thesis. This book disaggregates the elements of the dissertation and provides the student with a description, definition, and example of each dissertation element. The author presents multiple viewpoints that include both quantitative and qualitative approaches.…

  3. DOCKTITE-a highly versatile step-by-step workflow for covalent docking and virtual screening in the molecular operating environment.

    PubMed

    Scholz, Christoph; Knorr, Sabine; Hamacher, Kay; Schmidt, Boris

    2015-02-23

    The formation of a covalent bond with the target is essential for a number of successful drugs, yet tools for covalent docking without significant restrictions regarding warhead or receptor classes are rare and limited in use. In this work we present DOCKTITE, a highly versatile workflow for covalent docking in the Molecular Operating Environment (MOE) combining automated warhead screening, nucleophilic side chain attachment, pharmacophore-based docking, and a novel consensus scoring approach. The comprehensive validation study includes pose predictions of 35 protein/ligand complexes which resulted in a mean RMSD of 1.74 Å and a prediction rate of 71.4% with an RMSD below 2 Å, a virtual screening with an area under the curve (AUC) for the receiver operating characteristics (ROC) of 0.81, and a significant correlation between predicted and experimental binding affinities (ρ = 0.806, R(2) = 0.649, p < 0.005).

  4. A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor

    PubMed Central

    Lun, Aaron T.L.; McCarthy, Davis J.; Marioni, John C.

    2016-01-01

    Single-cell RNA sequencing (scRNA-seq) is widely used to profile the transcriptome of individual cells. This provides biological resolution that cannot be matched by bulk RNA sequencing, at the cost of increased technical noise and data complexity. The differences between scRNA-seq and bulk RNA-seq data mean that the analysis of the former cannot be performed by recycling bioinformatics pipelines for the latter. Rather, dedicated single-cell methods are required at various steps to exploit the cellular resolution while accounting for technical noise. This article describes a computational workflow for low-level analyses of scRNA-seq data, based primarily on software packages from the open-source Bioconductor project. It covers basic steps including quality control, data exploration and normalization, as well as more complex procedures such as cell cycle phase assignment, identification of highly variable and correlated genes, clustering into subpopulations and marker gene detection. Analyses were demonstrated on gene-level count data from several publicly available datasets involving haematopoietic stem cells, brain-derived cells, T-helper cells and mouse embryonic stem cells. This will provide a range of usage scenarios from which readers can construct their own analysis pipelines. PMID:27909575

  5. A~fine fraction of soil used as an aerosol analogue during the DUNE experiment: sequential solubility in water with step-by-step decreasing pH

    NASA Astrophysics Data System (ADS)

    Aghnatios, C.; Losno, R.; Dulac, F.

    2014-02-01

    A soil sample collected in a desert aerosol source area near Douz (South Tunisia) was sieved at 20 μm in order to extract the fraction similar to an aerosol generated by wind and used to seed mesocosms during the DUNE experiment. In the present work, this "aerosol-like" fine dust was sequentially leached by short contacts with water at pHs decreasing from 7 to 1. These pHs are representative of various environmental wet conditions, the lowest of which could be reached during cloud conditions. The evolution of the solubility from the highest to the lowest pHs provides information on the necessary strength for the solubilisation of a given element and its lability. The behaviour of the elemental fractional solubility is sorted into two groups: (i) Ca, Sr, Ba, Mn, P constitute group 1, with a solubility between 23% and 70% and with a maximum solubility at pH 3; (ii) whereas in group 2 (Al, Fe), the solubility is less than 2% with the highest release at pH 1. Similar solubility patterns in group 1 for Ca, P and Mn suggest a~possible association of the elements in the same minerals, most probably carbonates, which gives phosphorus an unexpected high lability.

  6. A fine fraction of soil used as an aerosol analogue during the DUNE experiment: sequential solubility in water, decreasing pH step-by-step

    NASA Astrophysics Data System (ADS)

    Aghnatios, C.; Losno, R.; Dulac, F.

    2014-09-01

    A soil sample collected in a desert aerosol source area near Douz (southern Tunisia) was dry-sieved at 20 μm in order to extract the fraction similar to a wind-generated aerosol, and was used to seed mesocosms during the DUNE experiment (a DUst experiment in a low Nutrient, low chlorophyll Ecosystem). In this work, said "aerosol-like" fine dust was sequentially leached by short contacts with water at initial pHs, decreasing from seven to one, representing various wet environmental conditions. For each step, the solubility of a given element is calculated as the amount of its dissolved fraction, relative to its total amount. The evolution of this fractional solubility from the highest to lowest pHs provides information on the chemical strength needed to solubilise a given element and its lability. The behaviour of the elemental solubility was sorted into two groups: (1) Ca, Sr, Ba, Mn, and P, with a solubility between 23% and 70%, and a maximum sequential solubility at pH 3; (2) Al and Fe, with a solubility of less than 2% and the highest release at pH 1. Similar solubility patterns in group 1 for Ca, P, and Mn suggest a possible association of the elements in the same minerals, most probably carbonates.

  7. Cost Analysis Step by Step: A How-to Guide for Planners and Providers of Welfare-to-Work and Other Employment and Training Programs. Connections to Work.

    ERIC Educational Resources Information Center

    Greenberg, David H.; Appenzeller, Ute

    Intended for planners and providers of welfare-to-work and other employment and training programs, this guide explains the steps entailed in conducting a cost analysis. The following topics are discussed in the book's six chapters: use of cost analysis before programs and during their implementation; basics of conducting a cost analysis (issue of…

  8. Step-by-Step Design of an FPGA-Based Digital Compensator for DC/DC Converters Oriented to an Introductory Course

    ERIC Educational Resources Information Center

    Zumel, P.; Fernandez, C.; Sanz, M.; Lazaro, A.; Barrado, A.

    2011-01-01

    In this paper, a short introductory course to introduce field-programmable gate array (FPGA)-based digital control of dc/dc switching power converters is presented. Digital control based on specific hardware has been at the leading edge of low-medium power dc/dc switching converters in recent years. Besides industry's interest in this topic, from…

  9. Sustainable Materials Management (SMM) Web Academy Webinar Series: A Step-by-Step Guide to Conducting a Wasted Food Assessment with the Reducing Wasted Food & Packaging Toolkit

    EPA Pesticide Factsheets

    This is a webinar page for the Sustainable Management of Materials (SMM) Web Academy webinar titled Let’s WRAP (Wrap Recycling Action Program): Best Practices to Boost Plastic Film Recycling in Your Community

  10. The Comprehensive Guide to Successful Conferences and Meetings. Detailed Instructions and Step-by-Step Checklists. The Jossey-Bass Higher Education Series.

    ERIC Educational Resources Information Center

    Nadler, Leonard; Nadler, Zeace

    Practical advice on every facet of planning and running conferences, meetings, or similar events is given in this book, which includes numerous checklists useful for meetings of any length and in any setting. The 21 chapters cover the following: the changing conference and meeting scene; designing the conference; four useful designs (1-day, 3-day,…

  11. Notes on Experiments.

    ERIC Educational Resources Information Center

    Physics Education, 1988

    1988-01-01

    Described are five physics activities including two superconductor projects, synchronizing video camera movements, electrical analysis of a bicycle, and apparatus for the measurement of thermal conductivity. (YP)

  12. Online Class Size, Note Reading, Note Writing and Collaborative Discourse

    ERIC Educational Resources Information Center

    Qiu, Mingzhu; Hewitt, Jim; Brett, Clare

    2012-01-01

    Researchers have long recognized class size as affecting students' performance in face-to-face contexts. However, few studies have examined the effects of class size on exact reading and writing loads in online graduate-level courses. This mixed-methods study examined relationships among class size, note reading, note writing, and collaborative…

  13. Middle School Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1983

    1983-01-01

    Demonstrations, experiments, and classroom activities/materials for middle school science are presented. These include: additive color mixing demonstration; electricity activity and worksheet; atmospheric pressure "magic" demonstration; homemade microbalance; energy from soap bubbles; and a model used to demonstrate muscle pairs and how…

  14. Middle School Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1981

    1981-01-01

    Describes activities, demonstrations, and materials suitable for middle school science, including investigations on solar energy, surface tension, exploding cottages, worms and light, airplanes, depolarizing simple cells, and the thermal expansion of metals. (JN)

  15. Middle School Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1982

    1982-01-01

    Provides instructions for constructing a "Heath Robinson compass" and describes activities/demonstrations focusing on energy waves, opposing forces, illusory motion with paper movies, and motion of vessels in air and in water. (JN)

  16. Middle School Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1981

    1981-01-01

    Provides directions for constructing a wooden or metal weather vane. Also describes the construction of a "Boomerang Drum," a machine which can store and release energy, and suggests activities for use with it. (DS)

  17. Middle School Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1981

    1981-01-01

    Provides science activities and teaching hints appropriate for the middle school sciences including making a domino "gunpowder fuse" that detonates a mousetrap "bomb," using fishing rods and bicycles as teaching aids, constructing lead holders, and teaching chromatography. (DC)

  18. Fiches pratiques (Practical Notes).

    ERIC Educational Resources Information Center

    Francais dans le Monde, 1987

    1987-01-01

    Five ideas for class activities at different levels and for various audiences are described. They include a card game, exercises on French wines, a personalities game, and study of a Baudelaire poem. (MSE)

  19. Middle School Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1982

    1982-01-01

    Presents procedures, demonstrations, activities, and teaching suggestions on topics appropriate for middle school science including a simple electrolysis cell, conversion factors, energy, solubilities of salts, condensers, and a worksheet for studying coppice woodlands. (DC)

  20. Analyzing Sound Waves Produced by Musical Notes & Chords.

    ERIC Educational Resources Information Center

    Cassidy, Michael

    This project description is designed to show how graphing calculators and calculator-based laboratories (CBL) can be used to explore topics in the physics of sound. The activities address topics such as sound waves, musical notes, and chords. Teaching notes, calculator instructions, and blackline masters are included. (MM)

  1. Cache Note from Peary's North Greenland Expedition of 1892.

    ERIC Educational Resources Information Center

    Haverkamp, Beth; Schamel, Wynell

    1995-01-01

    Presents instructional materials and suggestions for using primary source documents regarding Admiral Peary's search for the North Pole. Cache notes were brief dispatches left for the press in ice hutches along with provisions and maps. Includes a photocopy of a cache note from Peary's expedition with suggested research topics and activities. (MJP)

  2. Notes from the Field: Ebola Virus Disease Response Activities During a Mass Displacement Event After Flooding--Freetown, Sierra Leone, September-November, 2015.

    PubMed

    Ratto, Jeffrey; Ivy, Wade; Purfield, Anne; Bangura, James; Omoko, Anthony; Boateng, Isaac; Duffy, Nadia; Sims, George; Beamer, Bryan; Pi-Sunyer, Teresa; Kamara, Sarian; Conteh, Sulaiman; Redd, John

    2016-02-26

    Since the start of the Ebola virus disease (Ebola) outbreak in West Africa, Sierra Leone has reported 8,706 confirmed Ebola cases and 3,956 deaths. During September 15-16, 2015, heavy rains flooded the capital, Freetown, resulting in eight deaths, home and property destruction, and thousands of persons in need of assistance. By September 27, approximately 13,000 flood-affected persons registered for flood relief services from the government. On September 17, two stadiums in Freetown were opened to provide shelter and assistance to flood-affected residents; a total of approximately 3,000 persons stayed overnight in both stadiums (Sierra Leone Ministry of Health and Sanitation, personal communication, September 2015). On the same day the stadiums were opened to flood-affected persons, the Ministry of Health and Sanitation (MoHS) and Western Area Ebola Response Center (WAERC) staff members from CDC, the World Health Organization (WHO), and the African Union evaluated the layout, logistics, and services at both stadiums and identified an immediate need to establish Ebola response activities. The patient in the last Ebola case in the Western Area, which includes Freetown, had died 37 days earlier, on August 11; however, transmission elsewhere in Sierra Leone was ongoing, and movement of persons throughout the country was common.

  3. Middle School Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1983

    1983-01-01

    Describes a soap bubble motor, house insulation models, using hot-water bottles as heat sources, solar mobile, surface tension boat, evaporative cooling experiments, six activities on heat, and a magic trick based on friction. Also discusses using the Cambion Electronics Kit to introduce junior high students to the subject. (JM)

  4. Middle School Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1983

    1983-01-01

    Describes construction and use of pivots for science equipment and a pin-hole camera (made out of newspaper) for observing solar eclipses. Also describes a method for displaying spectra with a raybox and modification/use of a one-shot submarine (used in floating/sinking activities). (JN)

  5. Middle School Science Notes.

    ERIC Educational Resources Information Center

    School Science Review, 1980

    1980-01-01

    Describes equipment, experiments, and activities useful in middle school science instruction, including demonstrating how strong paper can be, the inclined plane illusion, a simplified diet calculation, a magnetic levitator, science with soap bubbles, a model motor and dynamo, and a pocketed sorter for safety glasses. (SK)

  6. The NIRCam Optical Telescope Simulator (NOTES)

    NASA Technical Reports Server (NTRS)

    Kubalak, David; Hakun, Claef; Greeley, Bradford; Eichorn, William; Leviton, Douglas; Guishard, Corina; Gong, Qian; Warner, Thomas; Bugby, David; Robinson, Frederick; Lansing, Peter; Garza, Mario; Kirk, Jeffrey

    2007-01-01

    The Near Infra-Red Camera (NIRCam), the 0.6-5.0 micron imager and wavefront sensing instrument for the James Webb Space Telescope (JWST), will be used on orbit both as a science instrument, and to tune the alignment of the telescope. The NIRCam Optical Telescope Element Simulator (NOTES) will be used during ground testing to provide an external stimulus to verify wavefront error, imaging characteristics, and wavefront sensing performance of this crucial instrument. NOTES is being designed and built by NASA Goddard Space Flight Center with the help of Swales Aerospace and Orbital Sciences Corporation. It is a single-point imaging system that uses an elliptical mirror to form an U20 image of a point source. The point source will be fed via optical fibers from outside the vacuum chamber. A tip/tilt mirror is used to change the chief ray angle of the beam as it passes through the aperture stop and thus steer the image over NIRCam's field of view without moving the pupil or introducing field aberrations. Interchangeable aperture stop elements allow us to simulate perfect JWST wavefronts for wavefront error testing, or introduce transmissive phase plates to simulate a misaligned JWST segmented mirror for wavefront sensing verification. NOTES will be maintained at an operating temperature of 80K during testing using thermal switches, allowing it to operate within the same test chamber as the NIRCam instrument. We discuss NOTES' current design status and on-going development activities.

  7. Detail, external parabolic antenna (later addition). Note how waveguide was ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail, external parabolic antenna (later addition). Note how waveguide was cut to remove active portion of antenna. - Western Union Telegraph Company, Jennerstown Relay, Laurel Summit Road off U.S. 30, Laughlintown, Westmoreland County, PA

  8. Notes on sedimentation activities calendar year 1988

    USGS Publications Warehouse

    ,

    1989-01-01

    This report is a digest of information furnished by Federal agencies conducting sedimentation investigations. The decision to publish the report was made in 1946, from a proposal by the Chairman of the Federal Interagency River Basin Committee, Subcommittee on Ground Water. The subcommittee approved the proposal and agreed to issue this report as a means of effecting better coordination of the work of various Federal agencies in the field of sedimentation. The report was issued on a quarterly basis in 1946 and 1947, from 1948 to 1953 reports were issued every 6 months, and from 1954 to the present, the report has been issued annually.

  9. Notes on sedimentation activities calendar year 1984

    USGS Publications Warehouse

    ,

    1985-01-01

    This report is a digest of information furnished by Federal agencies conducting sedimentation investigations. The decision to publish the report was made in 1946, from a proposal by the Chairman of the Federal Interagency River Basin Committee, Subcommittee on Ground Water. The Subcommittee approved the proposal and agreed to issue this report as a means of effecting better coordination of the work of various Federal agencies in the field of sedimentation. From 1946 to 1947 the report was issued on a quarterly basis, from 1948 to 1953 reports were issued every 6 months, and from 1954 to the present the report has been issued annually.

  10. Notes on sedimentation activities calendar year 1990

    USGS Publications Warehouse

    ,

    1991-01-01

    This report is a digest of information furnished by Federal agencies conducting sedimentation investigations. The decision to publish the report was made in 1946, from a proposal by the Chairman of the Federal Interagency River Basin Committee, Subcommittee on Sedimentation. The subcommittee approved the proposal and agreed to issue this report as a means of effecting better coordination of the work of various Federal agencies in the field of sedimentation. The report was issued on a quarterly basis in 1946 and 1947, from 1948 to 1953 reports were issued every 6 months, and from 1954 to the present, the report has been issued annually.

  11. Notes on sedimentation activities calendar year 1989

    USGS Publications Warehouse

    ,

    1990-01-01

    This report is a digest of information furnished by Federal agencies conducting sedimentation investigations. The decision to publish the report was made in 1946, from a proposal by the Chairman of the Federal Interagency River Basin Committee, Subcommittee on Ground Water. The subcommittee approved the proposal and agreed to issue this report as a means of effecting better coordination of the work of various Federal agencies in the field of sedimentation. The report was issued on a quarterly basis in 1946 and 1947, from 1948 to 1953 reports were issued every 6 months, and from 1954 to the present, the report has been issued annually.

  12. Notes on sedimentation activities calendar year 1992

    USGS Publications Warehouse

    ,

    1994-01-01

    This report is a digest of information furnished by Federal agencies conducting sedimentation investigations. The decision to publish the report was made in 1946, from a proposal by the Chairman of the Federal Interagency River Basin Committee, Subcommittee on Sedimentation. The subcommittee approved the proposal and agreed to issue this report as a means of effecting better coordination of the work of various Federal agencies in the field of sedimentation. The report was issued on a quarterly basis in 1946 and 1947, from 1948 to 1953 reports were issued every 6 months, and from 1954 to present, the report has been issued annually.

  13. Notes on sedimentation activities calendar year 1985

    USGS Publications Warehouse

    ,

    1986-01-01

    This report is a digest of information furnished by Federal agencies conducting sedimentation investigations. The decision to publish the report was made in 1946, from a proposal by the Chairman of the Federal Interagercy River Basin Committee, Subcommittee on Ground Water. The subcommittee approved the proposal and agreed to issue this report as a means of effecting better coordination of the work of various Federal agencies in the field of sedimentation. From 1946 to 1947, the report was issued on a quarterly basis; from 1948 to 1953, reports were issued every 6 months; and from 1954 to the present, the report has been issued annually.

  14. Notes on sedimentation activities calendar year 1987

    USGS Publications Warehouse

    ,

    1988-01-01

    This report is a digest of information furnished by Federal agencies conducting sedimentation investigations. The decision to publish the report was made in 1946, from a proposal by the Chairman of the Federal Interagency River Basin Committee, Subcommittee on Ground Water. The subcommittee approved the proposal and agreed to issue this report as a means of effecting better coordination of the work of various Federal agencies in the field of sedimentation. The report was issued on a quarterly basis in 1946 and 1947, from 1948 to 1953 reports were issued every 6 months, and from 1954 to the present, the report has been issued annually.

  15. Notes on sedimentation activities calendar year 1991

    USGS Publications Warehouse

    ,

    1992-01-01

    This report is a digest of information furnished by Federal agencies conducting sedimentation investigations. The decision to publish the report was made in 1946, from a proposal by the Chairman of the Federal Interagency River Basin Committee, Subcommittee on Sedimentation. The subcommittee approved the proposal and agreed to issue this report as a means of effecting better coordination of the work of various Federal agencies in the field of sedimentation. The report was issued on a quarterly basis in 1946 and 1947, from 1948 to 1953 reports were issued every 6 months, and from 1954 to the present, the report has been issued annually.

  16. The hybrid progress note: semiautomating daily progress notes to achieve high-quality documentation and improve provider efficiency.

    PubMed

    Kargul, George J; Wright, Scott M; Knight, Amy M; McNichol, Mary T; Riggio, Jeffrey M

    2013-01-01

    Health care institutions are moving toward fully functional electronic medical records (EMRs) that promise improved documentation, safety, and quality of care. However, many hospitals do not yet use electronic documentation. Paper charting, including writing daily progress notes, is time-consuming and error prone. To improve the quality of documentation at their hospital, the authors introduced a highly formatted paper note template (hybrid note) that is prepopulated with data from the EMR. Inclusion of vital signs and active medications improved from 75.5% and 60% to 100% (P < .001), respectively. The use of unapproved abbreviations in the medication list decreased from 13.3% to 0% (P < .001). Prepopulating data enhances provider efficiency. Interviews of key clinician leaders also suggest that the initiative is well accepted and that documentation quality is enhanced. The hybrid progress note improves documentation and provider efficiency, promotes quality care, and initiates the development of the forthcoming electronic progress note.

  17. Station Program Note Pull Automation

    NASA Technical Reports Server (NTRS)

    Delgado, Ivan

    2016-01-01

    Upon commencement of my internship, I was in charge of maintaining the CoFR (Certificate of Flight Readiness) Tool. The tool acquires data from existing Excel workbooks on NASA's and Boeing's databases to create a new spreadsheet listing out all the potential safety concerns for upcoming flights and software transitions. Since the application was written in Visual Basic, I had to learn a new programming language and prepare to handle any malfunctions within the program. Shortly afterwards, I was given the assignment to automate the Station Program Note (SPN) Pull process. I developed an application, in Python, that generated a GUI (Graphical User Interface) that will be used by the International Space Station Safety & Mission Assurance team here at Johnson Space Center. The application will allow its users to download online files with the click of a button, import SPN's based on three different pulls, instantly manipulate and filter spreadsheets, and compare the three sources to determine which active SPN's (Station Program Notes) must be reviewed for any upcoming flights, missions, and/or software transitions. Initially, to perform the NASA SPN pull (one of three), I had created the program to allow the user to login to a secure webpage that stores data, input specific parameters, and retrieve the desired SPN's based on their inputs. However, to avoid any conflicts with sustainment, I altered it so that the user may login and download the NASA file independently. After the user has downloaded the file with the click of a button, I defined the program to check for any outdated or pre-existing files, for successful downloads, to acquire the spreadsheet, convert it from a text file to a comma separated file and finally into an Excel spreadsheet to be filtered and later scrutinized for specific SPN numbers. Once this file has been automatically manipulated to provide only the SPN numbers that are desired, they are stored in a global variable, shown on the GUI, and

  18. Bubbles: Films, Foams & Fizz. Ideas in Science. Notes for Teachers.

    ERIC Educational Resources Information Center

    Murphy, Pat, Ed.

    Five activities dealing with bubbles are presented. Information provided with the activities includes introductory and/or background information; notes on pre-activity preparations; lists of science themes and skills fostered; time frame; list of materials needed; student procedures; and instructional strategies. A teaching guide with detailed…

  19. Notes.

    ERIC Educational Resources Information Center

    Physics Teacher, 1979

    1979-01-01

    Some topics included are: the relative merits of a programmable calculator and a microcomputer; the advantages of acquiring a sound-level meter for the laboratory; how to locate a virtual image in a plane mirror; center of gravity of a student; and how to demonstrate interference of light using two cords.

  20. Possibilities of lasers within NOTES.

    PubMed

    Stepp, Herbert; Sroka, Ronald

    2010-10-01

    Lasers possess unique properties that render them versatile light sources particularly for NOTES. Depending on the laser light sources used, diagnostic as well as therapeutic purposes can be achieved. The diagnostic potential offered by innovative concepts such as new types of ultra-thin endoscopes and optical probes supports the physician with optical information of ultra-high resolution, tissue discrimination and manifold types of fluorescence detection. In addition, the potential 3-D capability promises enhanced recognition of tissue type and pathological status. These diagnostic techniques might enable or at least contribute to accurate and safe procedures within the spatial restrictions inherent with NOTES. The therapeutic potential ranges from induction of phototoxic effects over tissue welding, coagulation and tissue cutting to stone fragmentation. As proven in many therapeutic laser endoscopic treatment concepts, laser surgery is potentially bloodless and transmits the energy without mechanical forces. Specialized NOTES endoscopes will likely incorporate suitable probes for improving diagnostic procedures, laser fibres with advantageous light delivery possibility or innovative laser beam manipulation systems. NOTES training centres may support the propagation of the complex handling and the safety aspects for clinical use to the benefit of the patient.

  1. EndNote at Lehigh.

    ERIC Educational Resources Information Center

    Siegler, Sharon; Simboli, Brian

    2002-01-01

    Describes the experiences of librarians at Lehigh University in implementing campus-wide use of EndNote, a citation management software package that allows users to create a searchable library of downloaded or manually entered references for any type of publication to be able to insert citations and format footnotes or endnotes within a…

  2. A brief note regarding randomization.

    PubMed

    Senn, Stephen

    2013-01-01

    This note argues, contrary to claims in this journal, that the possible existence of indefinitely many causal factors does not invalidate randomization. The effect of such factors has to be bounded by outcome, and since inference is based on a ratio of between-treatment-group to within-treatment-group variation, randomization remains valid.

  3. Applied Fluid Mechanics. Lecture Notes.

    ERIC Educational Resources Information Center

    Gregg, Newton D.

    This set of lecture notes is used as a supplemental text for the teaching of fluid dynamics, as one component of a thermodynamics course for engineering technologists. The major text for the course covered basic fluids concepts such as pressure, mass flow, and specific weight. The objective of this document was to present additional fluids…

  4. Lunar nomenclature: A dissenting note

    USGS Publications Warehouse

    Arthur, D.W.G.

    1976-01-01

    This note reviews the nature of the traditional (Ma??dler) lunar nomenclature and the recent developments based on the use of more than 2000 named provinces. It appears that the new nomenclature is less efficient than the old in many cases and may lead to an impossible publication situation. The unnecessary break with the past is especially critized. ?? 1976.

  5. A Note on Hamiltonian Graphs

    ERIC Educational Resources Information Center

    Skurnick, Ronald; Davi, Charles; Skurnick, Mia

    2005-01-01

    Since 1952, several well-known graph theorists have proven numerous results regarding Hamiltonian graphs. In fact, many elementary graph theory textbooks contain the theorems of Ore, Bondy and Chvatal, Chvatal and Erdos, Posa, and Dirac, to name a few. In this note, the authors state and prove some propositions of their own concerning Hamiltonian…

  6. Lecture Notes on Multigrid Methods

    SciTech Connect

    Vassilevski, P S

    2010-06-28

    The Lecture Notes are primarily based on a sequence of lectures given by the author while been a Fulbright scholar at 'St. Kliment Ohridski' University of Sofia, Sofia, Bulgaria during the winter semester of 2009-2010 academic year. The notes are somewhat expanded version of the actual one semester class he taught there. The material covered is slightly modified and adapted version of similar topics covered in the author's monograph 'Multilevel Block-Factorization Preconditioners' published in 2008 by Springer. The author tried to keep the notes as self-contained as possible. That is why the lecture notes begin with some basic introductory matrix-vector linear algebra, numerical PDEs (finite element) facts emphasizing the relations between functions in finite dimensional spaces and their coefficient vectors and respective norms. Then, some additional facts on the implementation of finite elements based on relation tables using the popular compressed sparse row (CSR) format are given. Also, typical condition number estimates of stiffness and mass matrices, the global matrix assembly from local element matrices are given as well. Finally, some basic introductory facts about stationary iterative methods, such as Gauss-Seidel and its symmetrized version are presented. The introductory material ends up with the smoothing property of the classical iterative methods and the main definition of two-grid iterative methods. From here on, the second part of the notes begins which deals with the various aspects of the principal TG and the numerous versions of the MG cycles. At the end, in part III, we briefly introduce algebraic versions of MG referred to as AMG, focusing on classes of AMG specialized for finite element matrices.

  7. Notes for Serials Cataloging. Second Edition.

    ERIC Educational Resources Information Center

    Geer, Beverley, Ed.; Caraway, Beatrice L., Ed.

    Notes are indispensable to serials cataloging. Researchers, reference librarians, and catalogers regularly use notes on catalog records and, as the audience for these notes has expanded from the local library community to the global Internet community, the need for notes to be cogent, clear, and useful is greater than ever. This book is a…

  8. Kindergarten Quantum Mechanics: Lecture Notes

    SciTech Connect

    Coecke, Bob

    2006-01-04

    These lecture notes survey some joint work with Samson Abramsky as it was presented by me at several conferences in the summer of 2005. It concerns 'doing quantum mechanics using only pictures of lines, squares, triangles and diamonds'. This picture calculus can be seen as a very substantial extension of Dirac's notation, and has a purely algebraic counterpart in terms of so-called Strongly Compact Closed Categories (introduced by Abramsky and I which subsumes my Logic of Entanglement. For a survey on the 'what', the 'why' and the 'hows' I refer to a previous set of lecture notes. In a last section we provide some pointers to the body of technical literature on the subject.

  9. A note on "Kepler's equation".

    NASA Astrophysics Data System (ADS)

    Dutka, J.

    1997-07-01

    This note briefly points out the formal similarity between Kepler's equation and equations developed in Hindu and Islamic astronomy for describing the lunar parallax. Specifically, an iterative method for calculating the lunar parallax has been developed by the astronomer Habash al-Hasib al-Marwazi (about 850 A.D., Turkestan), which is surprisingly similar to the iterative method for solving Kepler's equation invented by Leonhard Euler (1707 - 1783).

  10. Recognizing Exponential Growth. Classroom Notes

    ERIC Educational Resources Information Center

    Dobbs, David E.

    2004-01-01

    Two heuristic and three rigorous arguments are given for the fact that functions of the form Ce[kx], with C an arbitrary constant, are the only solutions of the equation dy/dx=ky where k is constant. Various of the proofs in this self-contained note could find classroom use in a first-year calculus course, an introductory course on differential…

  11. Lecture notes for criticality safety

    SciTech Connect

    Fullwood, R.

    1992-03-01

    These lecture notes for criticality safety are prepared for the training of Department of Energy supervisory, project management, and administrative staff. Technical training and basic mathematics are assumed. The notes are designed for a two-day course, taught by two lecturers. Video tapes may be used at the options of the instructors. The notes provide all the materials that are necessary but outside reading will assist in the fullest understanding. The course begins with a nuclear physics overview. The reader is led from the macroscopic world into the microscopic world of atoms and the elementary particles that constitute atoms. The particles, their masses and sizes and properties associated with radioactive decay and fission are introduced along with Einstein`s mass-energy equivalence. Radioactive decay, nuclear reactions, radiation penetration, shielding and health-effects are discussed to understand protection in case of a criticality accident. Fission, the fission products, particles and energy released are presented to appreciate the dangers of criticality. Nuclear cross sections are introduced to understand the effectiveness of slow neutrons to produce fission. Chain reactors are presented as an economy; effective use of the neutrons from fission leads to more fission resulting in a power reactor or a criticality excursion. The six-factor formula is presented for managing the neutron budget. This leads to concepts of material and geometric buckling which are used in simple calculations to assure safety from criticality. Experimental measurements and computer code calculations of criticality are discussed. To emphasize the reality, historical criticality accidents are presented in a table with major ones discussed to provide lessons-learned. Finally, standards, NRC guides and regulations, and DOE orders relating to criticality protection are presented.

  12. Note on new KLT relations

    NASA Astrophysics Data System (ADS)

    Feng, Bo; He, Song; Huang, Rijun; Jia, Yin

    2010-10-01

    In this short note, we present two results about KLT relations discussed in recent several papers. Our first result is the re-derivation of Mason-Skinner MHV amplitude by applying the S n-3 permutation symmetric KLT relations directly to MHV amplitude. Our second result is the equivalence proof of the newly discovered S n-2 permutation symmetric KLT relations and the well-known S n-3 permutation symmetric KLT relations. Although both formulas have been shown to be correct by BCFW recursion relations, our result is the first direct check using the regularized definition of the new formula.

  13. What Predicts Skill in Lecture Note Taking?

    ERIC Educational Resources Information Center

    Peverly, Stephen T.; Ramaswamy, Vivek; Brown, Cindy; Sumowski, James; Alidoost, Moona; Garner, Joanna

    2007-01-01

    Despite the importance of good lecture notes to test performance, very little is known about the cognitive processes that underlie effective lecture note taking. The primary purpose of the 2 studies reported (a pilot study and Study 1) was to investigate 3 processes hypothesized to be significantly related to quality of notes: transcription…

  14. Promoting Knowledge Transfer with Electronic Note Taking

    ERIC Educational Resources Information Center

    Katayama, Andrew D.; Shambaugh, R. Neal; Doctor, Tasneem

    2005-01-01

    We investigated the differences between (a) copying and pasting text versus typed note-taking methods of constructing study notes simultaneously with (b) vertically scaffolded versus horizontally scaffold notes on knowledge transfer. Forty-seven undergraduate educational psychology students participated. Materials included 2 electronic…

  15. 32 CFR 806b.5 - Personal notes.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false Personal notes. 806b.5 Section 806b.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE ADMINISTRATION PRIVACY ACT PROGRAM... notes on individuals used as memory aids. Personal notes may become Privacy Act records if they...

  16. 32 CFR 806b.5 - Personal notes.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false Personal notes. 806b.5 Section 806b.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE ADMINISTRATION PRIVACY ACT PROGRAM... notes on individuals used as memory aids. Personal notes may become Privacy Act records if they...

  17. 32 CFR 806b.5 - Personal notes.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false Personal notes. 806b.5 Section 806b.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE ADMINISTRATION PRIVACY ACT PROGRAM... notes on individuals used as memory aids. Personal notes may become Privacy Act records if they...

  18. 32 CFR 806b.5 - Personal notes.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false Personal notes. 806b.5 Section 806b.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE ADMINISTRATION PRIVACY ACT PROGRAM... notes on individuals used as memory aids. Personal notes may become Privacy Act records if they...

  19. 32 CFR 806b.5 - Personal notes.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Personal notes. 806b.5 Section 806b.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE ADMINISTRATION PRIVACY ACT PROGRAM... notes on individuals used as memory aids. Personal notes may become Privacy Act records if they...

  20. Kepler Data Release 4 Notes

    NASA Technical Reports Server (NTRS)

    Van Cleve, Jeffrey (Editor); Jenkins, Jon; Caldwell, Doug; Allen, Christopher L.; Batalha, Natalie; Bryson, Stephen T.; Chandrasekaran, Hema; Clarke, Bruce D.; Cote, Miles T.; Dotson, Jessie L.; Gilliland, Ron; Girouard, Forrest; Haas, Michael R.; Hall, Jennifer; Ibrahim, Khadeejah; Klaus, Todd; Kolodziejczak, Jeff; Li, Jie; McCauliff, Sean D.; Middour, Christopher K.; Pletcher, David L.; Quintana, Elisa V.; Tenenbaum, Peter G.; Twicken, Joe; Uddin, Akm Kamal

    2010-01-01

    The Data Analysis Working Group have released long and short cadence materials, including FFIs and Dropped Targets for the Public. The Kepler Science Office considers Data Release 4 to provide "browse quality" data. These notes have been prepared to give Kepler users of the Multimission Archive at STScl (MAST) a summary of how the data were collected and prepared, and how well the data processing pipeline is functioning on flight data. They will be updated for each release of data to the public archive and placed on MAST along with other Kepler documentation, at http://archive.stsci.edu/kepler/documents.html. Data release 3 is meant to give users the opportunity to examine the data for possibly interesting science and to involve the users in improving the pipeline for future data releases. To perform the latter service, users are encouraged to notice and document artifacts, either in the raw or processed data, and report them to the Science Office.

  1. Note Passing and Gendered Discipline in Vietnamese Schools

    ERIC Educational Resources Information Center

    Horton, Paul

    2015-01-01

    While researchers agree that note passing is predominantly an activity engaged in by girls, there has been relatively little consideration of why this is the case. In this article, I argue that gendered expectations about the appropriate characters of boys and girls in Vietnam are incorporated into the disciplinary framework of schools, and that…

  2. Taxonomy of Lecture Note-Taking Skills and Subskills

    ERIC Educational Resources Information Center

    Al-Musalli, Alaa M.

    2015-01-01

    Note taking (NT) in lectures is as active a skill as listening, which stimulates it, and as challenging as writing, which is the end product. Literature on lecture NT misses an integration of the processes involved in listening with those in NT. In this article, a taxonomy is proposed of lecture NT skills and subskills based on a similar list…

  3. Engaging patients through open notes: an evaluation using mixed methods

    PubMed Central

    Esch, Tobias; Mejilla, Roanne; Anselmo, Melissa; Podtschaske, Beatrice; Delbanco, Tom; Walker, Jan

    2016-01-01

    Objectives (A) To gain insights into the experiences of patients invited to view their doctors’ visit notes, with a focus on those who review multiple notes; (B) to examine the relationships among fully transparent electronic medical records and quality of care, the patient-doctor relationship, patient engagement, self-care, self-management skills and clinical outcomes. Design Mixed methods qualitative study: analyses of survey data, including content analysis of free-text answers, and quantitative-descriptive measures combined with semistructured individual interviews, patient activation measures, and member checks. Setting Greater Boston, USA. Participants Patients cared for by primary care physicians (PCPs) at the Beth Israel Deaconess Medical Center who had electronic access to their PCP visit notes. Among those submitting surveys, 576 free-text answers were identified and analysed (414 from female patients, 162 from male patients; 23–88 years). In addition, 13 patients (9 female, 4 male; 58–87 years) were interviewed. Results Patient experiences indicate improved understanding (of health information), better relationships (with doctors), better quality (adherence and compliance; keeping track) and improved self-care (patient-centredness, empowerment). Patients want more doctors to offer access to their notes, and some wish to contribute to their generation. Those patients with repeated experience reviewing notes express fewer concerns and more perceived benefits. Conclusions As the use of fully transparent medical records spreads, it is important to gain a deeper understanding of possible benefits or harms, and to characterise target populations that may require varying modes of delivery. Patient desires for expansion of this practice extend to specialty care and settings beyond the physician's office. Patients are also interested in becoming involved actively in the generation of their medical records. The OpenNotes movement may increase patient

  4. New NOTES Clinical Training and Program Development.

    PubMed

    Saxena, Payal; Khashab, Mouen A

    2016-04-01

    Natural orifice translumenal endoscopic surgery (NOTES) is an intense area of research, and is arguably the most significant endoscopic innovation of this decade. Training for new NOTES is a relatively long, encompassing advanced endoscopy training, mastery of endoscopic dexterity within the narrow submucosal or "third space" with an in-depth understanding of the tissue planes. Proficiency with new closure and hemostatic devices is also essential. Few institutions worldwide can provide all the cognitive and technical elements essential to train new NOTES trainees. Trainees may need to spend time across several institutions to ensure safe and effective practice of new NOTES.

  5. Kepler Data Release 3 Notes

    NASA Technical Reports Server (NTRS)

    Cleve, Jeffrey E.

    2010-01-01

    This describes the collection of data and the processing done on it so when researchers around the world get the Kepler data sets (which are a set of pixels from the telescope of a particular target (star, galaxy or whatever) over a 3 month period) they can adjust their algorithms fro things that were done (like subtracting all of one particular wavelength for example). This is used to calibrate their own algorithms so that they know what it is they are starting with. It is posted so that whoever is accessing the publicly available data (not all of it is made public) can understand it .. (most of the Kepler data is under restriction for 1 - 4 years and is not available, but the handbook is for everyone (public and restricted) The Data Analysis Working Group have released long and short cadence materials, including FFls and Dropped Targets for the Public. The Kepler Science Office considers Data Release 3 to provide "browse quality" data. These notes have been prepared to give Kepler users of the Multimission Archive at STScl (MAST) a summary of how the data were collected and prepared, and how well the data processing pipeline is functioning on flight data. They will be updated for each release of data to the public archive and placed on MAST along with other Kepler documentation, at http:// archive.stsci.edu/kepler/documents.html .Data release 3 is meant to give users the opportunity to examine the data for possibly interesting science and to involve the users in improving the pipeline for future data releases. To perform the latter service, users are encouraged to notice and document artifacts, either in the raw or processed data, and report them to the Science Office.

  6. Mechanism of active transport: free energy dissipation and free energy transduction.

    PubMed Central

    Tanford, C

    1982-01-01

    The thermodynamic pathway for "chemiosmotic" free energy transduction in active transport is discussed with an ATP-driven Ca2+ pump as an illustrative example. Two innovations are made in the analysis. (i) Free energy dissipated as heat is rigorously excluded from overall free energy bookkeeping by focusing on the dynamic equilibrium state of the chemiosmotic process. (ii) Separate chemical potential terms for free energy donor and transported ions are used to keep track of the thermodynamic state of each substrate through the reaction cycle. These procedures clarify the mechanism of free energy transduction, even without step-by-step analysis. The results show that free energy exchange must occur in its entirety among protein-bound species. Imposition of conditions for an adequate rate of physiological function further indicates (i) that the standard free energy of hydrolysis of protein-bound ATP (to yield protein-bound products) needs to differ substantially from the standard free energy of hydrolysis in solution and (ii) that binding sites for the transported ions must have different affinities when facing opposite sides of the membrane. The results also demonstrate that step-by-step "basic" free energy changes (often used in the form of free energy level diagrams) are inherently unsuited for analysis of the mechanism of free energy transduction. PMID:6216483

  7. Note on Conditional Compilation in Standard ML

    DTIC Science & Technology

    1993-06-01

    eOmputer-Science No-te on Coridhitiom Cominliati"I~n Standard ML1 Nicholas Haines Edoardo Biagioni Robert Hiarper mom Brian G. Mimnes June 1993 CMU...CS-93. 11 TIC ELECTE f 00..7733 %goo~~OO Note on Conditioual Compilation in Standard ML Nicholas Haines Edoardo Biagioni Robert Harper Brian G. Milnes

  8. 34 CFR 674.31 - Promissory note.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false Promissory note. 674.31 Section 674.31 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION FEDERAL PERKINS LOAN PROGRAM Terms of Loans § 674.31 Promissory note. (a)...

  9. 34 CFR 674.31 - Promissory note.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false Promissory note. 674.31 Section 674.31 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION FEDERAL PERKINS LOAN PROGRAM Terms of Loans § 674.31 Promissory note. (a)...

  10. 34 CFR 674.31 - Promissory note.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false Promissory note. 674.31 Section 674.31 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION FEDERAL PERKINS LOAN PROGRAM Terms of Loans § 674.31 Promissory note. (a)...

  11. Model Disciplinary Policies. Research Note. Volume 0902

    ERIC Educational Resources Information Center

    Blazer, Christie

    2009-01-01

    This Research Note is in response to a request from the Office of Alternative Education to review and report on "model disciplinary policies" as used in school districts around the nation. The primary source of information used to prepare this Research Note came from a professional group identified by Alternative Education. The Advancement…

  12. Skin suicide note written in mehndi (henna).

    PubMed

    Behera, Chittaranjan; Swain, Rajanikanta; Bhardwaj, Daya Nand; Millo, Tabin

    2016-03-01

    Suicide messages on the skin are rare. Until now, in all reported cases, the writing tool used by the victims has been a pen. We report a suicide case by hanging in which the victim had written a note on her palm in mehndi, or henna, at a wedding ceremony three days before the fatal act. The note was discovered at autopsy.

  13. 34 CFR 674.31 - Promissory note.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false Promissory note. 674.31 Section 674.31 Education..., DEPARTMENT OF EDUCATION FEDERAL PERKINS LOAN PROGRAM Terms of Loans § 674.31 Promissory note. (a) Promissory... monthly repayment amount if the institution chooses the option under § 674.33(b). (b) Provisions of...

  14. The Great Case-Teaching-Notes Debate

    ERIC Educational Resources Information Center

    Lundberg, Craig C.; Winn, Joan

    2005-01-01

    Teaching notes, sometimes called an instructor's manual, are routinely required to accompany written teaching cases that are submitted to case journals and case writing conferences. Although the content and organization of these notes have become fairly standardized, the literature on the case method contains relatively little discussion…

  15. Idea Bank: Duct Tape Note Twister

    ERIC Educational Resources Information Center

    McHenry, Molly

    2008-01-01

    In this article, the author relates how she observed a middle school math teacher deliver a miserable class. She realized that she did the same thing to her music students. To engage her students, she developed "Note Twister," a music reading game using duct tape to form musical notes and the basic premise behind the game,…

  16. Suicide Notes in Hong Kong in 2000

    ERIC Educational Resources Information Center

    Wong, Paul W. C.; Yeung, April W. M.; Chan, Wincy S. C.; Yip, Paul S. F.; Tang, Arthur K. H.

    2009-01-01

    Suicide notes have been regarded as one of the most informative data sources to understand the reasons why people commit suicide. However, there is a paucity of suicide note studies, leaving researchers with an assumption that this phenomenon remains static over time. This study examines this assumption by comparing the characteristics of…

  17. 29 CFR 785.24 - Principles noted in Portal-to-Portal Bulletin.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Principles noted in Portal-to-Portal Bulletin. 785.24... of Principles Preparatory and Concluding Activities § 785.24 Principles noted in Portal-to-Portal Bulletin. In November, 1947, the Administrator issued the Portal-to-Portal Bulletin (part 790 of...

  18. Mysore study: A study of suicide notes

    PubMed Central

    Namratha, P.; Kishor, M.; Sathyanarayana Rao, T. S.; Raman, Rajesh

    2015-01-01

    Background: Suicide is one of the leading causes of preventable deaths. Recent data suggest South India as one of the regions with highest suicide rates in the world. In 2013, 134,799 people committed suicide in India according to the statistics released by the National Crime Records Bureau. Suicide note is one of the most important sources to understand suicide, which may be beneficial in suicide prevention. Studies on suicidal notes from this part of the world are sparse. Objective: The aim was to study the themes in suicide notes that might be useful in prevention strategies. Materials and Methods: A descriptive study of all suicide notes of those individuals who committed suicide between 2010 and 2013 available with Police Department, Mysore district was obtained and analyzed. Results: A total of 22 suicide note were available. A majority of suicide note was in age group of 16–40 years (86%) and most were men (59%). All suicide notes were handwritten, the majority (70%) in regional language Kannada. Length of notes varied from just few words to few pages. Contents of suicide notes included apology/shame/guilt (80%), love for those left behind (55%) and instruction regarding practical affairs (23%). Most have blamed none for the act (50%). 23% mentioned that they are committing suicide to prove their innocence. 32% mentioned a last wish. Conclusion: The majority of suicidal note contained “guilt” which is a strong indicator of possible depression in deceased. Creating awareness about suicide among public and ensuring access to professionals trained in suicide prevention is need of the hour in this part of the world. PMID:26816426

  19. Effects of Guided Notes versus Completed Notes during Lectures on College Students' Quiz Performance

    ERIC Educational Resources Information Center

    Neef, Nancy A.; McCord, Brandon E.; Ferreri, Summer J.

    2006-01-01

    We compared the effects of guided lecture notes versus completed lecture notes on pre- to postlecture improvements in quiz performance across two sections of a college course. The results of a counterbalanced multielement design did not reveal consistent differences between the two note formats on students' mean quiz scores. However, fewer errors…

  20. Teaching with Student Math Notes.

    ERIC Educational Resources Information Center

    National Council of Teachers of Mathematics, Inc., Reston, VA.

    Since 1982, the National Council of Teachers of Mathematics has published a student periodical five times a year. Each four-page issue focuses on a single theme, developing it from a simple opening-page activity through more challenging extensions at a higher level of understanding. In this document each four-page issue published from September,…

  1. Bank note recognition for the vision impaired.

    PubMed

    Hinwood, A; Preston, P; Suaning, G J; Lovell, N H

    2006-06-01

    Blind Australians find great difficulty in recognising bank notes. Each note has the same feel, with no Braille markings, irregular edges or other tangible features. In Australia, there is only one device available that can assist blind people recognise their notes. Internationally, there are devices available; however they are expensive, complex and have not been developed to cater for Australian currency. This paper discusses a new device, the MoneyTalker that takes advantage of the largely different colours and patterns on each Australian bank note and recognises the notes electronically, using the reflection and transmission properties of light. Different coloured lights are transmitted through the inserted note and the corresponding sensors detect distinct ranges of values depending on the colour of the note. Various classification algorithms were studied and the final algorithm was chosen based on accuracy and speed of recognition. The MoneyTalker has shown an accuracy of more than 99%. A blind subject has tested the device and believes that it is usable, compact and affordable. Based on the devices that are available currently in Australia, the MoneyTalker is an effective alternative in terms of accuracy and usability.

  2. EndNote 7.0.

    PubMed

    Eapen, Bell Raj

    2006-01-01

    EndNote is a useful software for online literature search and efficient bibliography management. It helps to format the bibliography according to the citation style of each journal. EndNote stores references in a library file, which can be shared with others. It can connect to online resources like PubMed and retrieve search results as per the search criteria. It can also effortlessly integrate with popular word processors like MS Word. The Indian Journal of Dermatology, Venereology and Leprology website has a provision to import references to EndNote.

  3. Notes from the beginning of time

    PubMed Central

    Sidman, Murray

    2002-01-01

    Some remembrances of things past, and their possible relevance to things now. These remembrances include notes about informality, research as a social process, student training and evaluation, research grants, thesis and dissertation proposals, and interdisciplinary collaboration. PMID:22478373

  4. 25 CFR 169.7 - Field notes.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... filed separately on tracing linen in such form that they may be folded readily for filing. Where field notes are placed on separate tracing linen, it will be necessary to place on the maps only a...

  5. 25 CFR 169.7 - Field notes.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... filed separately on tracing linen in such form that they may be folded readily for filing. Where field notes are placed on separate tracing linen, it will be necessary to place on the maps only a...

  6. 25 CFR 169.7 - Field notes.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... filed separately on tracing linen in such form that they may be folded readily for filing. Where field notes are placed on separate tracing linen, it will be necessary to place on the maps only a...

  7. 25 CFR 169.7 - Field notes.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... filed separately on tracing linen in such form that they may be folded readily for filing. Where field notes are placed on separate tracing linen, it will be necessary to place on the maps only a...

  8. 25 CFR 169.7 - Field notes.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... filed separately on tracing linen in such form that they may be folded readily for filing. Where field notes are placed on separate tracing linen, it will be necessary to place on the maps only a...

  9. CMSC-130 Introductory Computer Science, Lecture Notes

    DTIC Science & Technology

    1993-07-01

    The CMSC 130 Introductory Computer Science lecture notes are used in the classroom for teaching CMSC 130, an introductory computer science course...using the Ada programming language. Computer science , Language concepts, Ada language, Software concepts.

  10. Planning activity for internally generated reward goals in monkey amygdala neurons.

    PubMed

    Hernádi, István; Grabenhorst, Fabian; Schultz, Wolfram

    2015-03-01

    The best rewards are often distant and can only be achieved by planning and decision-making over several steps. We designed a multi-step choice task in which monkeys followed internal plans to save rewards toward self-defined goals. During this self-controlled behavior, amygdala neurons showed future-oriented activity that reflected the animal's plan to obtain specific rewards several trials ahead. This prospective activity encoded crucial components of the animal's plan, including value and length of the planned choice sequence. It began on initial trials when a plan would be formed, reappeared step by step until reward receipt, and readily updated with a new sequence. It predicted performance, including errors, and typically disappeared during instructed behavior. Such prospective activity could underlie the formation and pursuit of internal plans characteristic of goal-directed behavior. The existence of neuronal planning activity in the amygdala suggests that this structure is important in guiding behavior toward internally generated, distant goals.

  11. SMART: a system supporting medical activities in real-time.

    PubMed

    Pisanelli, D M; Consorti, F; Merialdo, P

    1997-01-01

    This paper describes the system SMART whose goal is real-time assistance to physicians who execute diagnostic or therapeutic protocols in a clinical context. SMART is able to retrieve a protocol from its knowledge base and to monitor its execution step by step for a single patient. Different protocols for different patients can be followed at the same time in a health care structure. The prototype realized supports the execution of protocols for evaluating surgical risks. It has been implemented according to the specifications given by the 4th Surgical Clinic of "Policlinico Umberto I" and reflects the activities actually performed in that hospital. However, the protocol model defined is general purpose and we envisage an easy application to other contexts and therefore to the informatization of other protocols.

  12. HEALTH DEPARTMENT REPORTS AND NOTES

    PubMed Central

    1913-01-01

    This new division of the Journal is specially designed to be of use to active Health Officers of the countries represented in the American Public Health Association. It will be unable to serve its true function unless the Health Officers are willing to coöperate by sending to the Journal copies of their reports, bulletins, new ordinances and personal information which will be of general interest. Furthermore it would be distinctly desirable if communications on subjects of general interest are submitted for publication in this division of the Journal. The management will further welcome any suggestions from Health Officers for the improvement of this division. All communications should be addressed to Selskar M. Gunn, Managing Editor, American Journal of Public Health, 755 Boylston St., Boston, Mass. PMID:18008967

  13. Epilepsy and music: practical notes.

    PubMed

    Maguire, M

    2017-04-01

    Music processing occurs via a complex network of activity far beyond the auditory cortices. This network may become sensitised to music or may be recruited as part of a temporal lobe seizure, manifesting as either musicogenic epilepsy or ictal musical phenomena. The idea that sound waves may directly affect brain waves has led researchers to explore music as therapy for epilepsy. There is limited and low quality evidence of an antiepileptic effect with the Mozart Sonata K.448. We do not have a pathophysiological explanation for the apparent dichotomous effect of music on seizures. However, clinicians should consider musicality when treating patients with antiepileptic medication or preparing patients for epilepsy surgery. Carbamazepine and oxcarbazepine each may cause a reversible altered appreciation of pitch. Surgical cohort studies suggest that musical memory and perception may be affected, particularly following right temporal lobe surgery, and discussion of this risk should form part of presurgical counselling.

  14. GeoMapApp Learning Activities: Enabling the democratisation of geoscience learning

    NASA Astrophysics Data System (ADS)

    Goodwillie, A. M.; Kluge, S.

    2011-12-01

    GeoMapApp Learning Activities (http://serc.carleton.edu/geomapapp) are step-by-step guided inquiry geoscience education activities that enable students to dictate the pace of learning. They can be used in the classroom or out of class, and their guided nature means that the requirement for teacher intervention is minimised which allows students to spend increased time analysing and understanding a broad range of geoscience data, content and concepts. Based upon GeoMapApp (http://www.geomapapp.org), a free, easy-to-use map-based data exploration and visualisation tool, each activity furnishes the educator with an efficient package of downloadable documents. This includes step-by-step student instructions and answer sheet; a teacher's edition annotated worksheet containing teaching tips, additional content and suggestions for further work; quizzes for use before and after the activity to assess learning; and a multimedia tutorial. The activities can be used by anyone at any time in any place with an internet connection. In essence, GeoMapApp Learning Activities provide students with cutting-edge technology, research-quality geoscience data sets, and inquiry-based learning in a virtual lab-like environment. Examples of activities so far created are student calculation and analysis of the rate of seafloor spreading, and present-day evidence on the seafloor for huge ancient landslides around the Hawaiian islands. The activities are designed primarily for students at the community college, high school and introductory undergraduate levels, exposing students to content and concepts typically found in those settings.

  15. What’s In a Note: Construction of a Suicide Note Corpus

    PubMed Central

    Pestian, John P.; Matykiewicz, Pawel; Linn-Gust, Michelle

    2012-01-01

    This paper reports on the results of an initiative to create and annotate a corpus of suicide notes that can be used for machine learning. Ultimately, the corpus included 1,278 notes that were written by someone who died by suicide. Each note was reviewed by at least three annotators who mapped words or sentences to a schema of emotions. This corpus has already been used for extensive scientific research. PMID:23170067

  16. Marginal notes for a centenary

    NASA Astrophysics Data System (ADS)

    Balázs, Lajos G.

    2001-10-01

    The Astronomical Research Institute of the Hungarian Academy of Sciences celebrated its centenary on the 20th of May 1999. Due to several political and economical crises it was not so easy in Central Europe in the past century to produce scientific results up to the prevailing international standards. Regular professional astronomical activity started in Hungary with the foundation of the university in Nagyszombat near to the present Bratislava. In 1777 the university was transferred to Buda and an observatory was installed in the tower of the royal palace. At the beginning of the 19th century, in 1815, a new university observatory was opened on the top of the Gellert Hill. The observatory was completely destroyed during the siege of the Buda castle in 1849. The other professional astronomical observatory of Karoly Nagy at the town Bicske, completed just at the beginning of the war in 1848-49, was never allowed to make a contribution. A new start for Hungarian astronomy came from Miklós Konkoly Thege when he established his private observatory in Ógyalla. A significant step in the life of the observatory was when it became the property of the state on the 20th of May, 1899. Astronomical photometry was chosen as the main research field of the new national observatory. The first world war led to the collapse of the Austro-Hungarian empire and resulted in the splitting of Ógyalla from Hungary. The instrumentation was transferred to Hungary and the government decided in 1921 to build a new institute on the Schwabian Hills close to Buda. Research on variable stars became the main field of the new institute, in particular the study of period changes of short-period cepheids. After the second world war solar physics was restarted in the institute and as a result a new independent observatory was formed in 1958. A significant development was the introduction of photoelectric observations. In the fifties a decision was made on building a new mountain station on

  17. A note on the "word-order problem" in agrammatism.

    PubMed

    Caplan, D

    1983-09-01

    This brief note has two parts. First, it presents an analysis of the ability of English agrammatic patients to assign the thematic roles of agent, instrument, theme, and locative to noun phrases in active and passive sentences and prepositional phrases. Data regarding this ability have been presented by Schwartz, Saffran, and Marin (Brain and Language, 10, 149-262 (1980) regarding comprehension, and by Saffran, Schwartz, and Marin (Brain and Language, 10, 263-280 (1980) regarding production. These authors claim their data show that English agrammatic aphasics do not map "word order" onto thematic information. However, a very simple set of principles accounts for all their results, including results which are discrepant in their treatment, but requires that English agrammatics assign thematic roles to NPs in part by virtue of the position of an NP in a sentence or a phrase. In the second part of this note, several issues raised by this re-analysis are briefly discussed.

  18. PAR-CLIP (Photoactivatable Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation): a Step-By-Step Protocol to the Transcriptome-Wide Identification of Binding Sites of RNA-Binding Proteins

    PubMed Central

    Spitzer, Jessica; Hafner, Markus; Landthaler, Markus; Ascano, Manuel; Farazi, Thalia; Wardle, Greg; Nusbaum, Jeff; Khorshid, Mohsen; Burger, Lukas; Zavolan, Mihaela; Tuschl, Thomas

    2014-01-01

    We recently developed a protocol for the transcriptome-wide isolation of RNA recognition elements readily applicable to any protein or ribonucleoprotein complex directly contacting RNA (including RNA helicases, polymerases, or nucleases) expressed in cell culture models either naturally or ectopically (Hafner et al., 2010). Briefly, immunoprecipitation of the RNA-binding protein of interest is followed by isolation of the crosslinked and coimmunoprecipitated RNA. In the course of lysate preparation and immunoprecipitation, the mRNAs are partially degraded using Ribonu-clease T1. The isolated crosslinked RNA fragments are converted into a cDNA library and deep-sequenced using Solexa technology (see Explanatory Chapter: Next Generation Sequencing). By introducing photoreactive nucleosides that generate characteristic sequence changes upon crosslinking (see below), our protocol allows one to separate RNA segments bound by the protein of interest from the background un-crosslinked RNAs. PMID:24581442

  19. From the sample preparation to the volume rendering images of small animals: A step by step example of a procedure to carry out the micro-CT study of the leafhopper insect Homalodisca vitripennis (Hemiptera: Cicadellidae)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Advances in micro-CT, digital computed tomography (CT) scan uses X-rays to make detailed pictures of structures inside of the body. Combining micro-CT with Digital Video Library systems, and linking this to Big Data, will change the way researchers, entomologist, and the public search and use anato...

  20. Online Notes: Differential Effects of Studying Complete or Partial Graphically Organized Notes

    ERIC Educational Resources Information Center

    Katayama, Andrew D.; Crooks, Steven M.

    2003-01-01

    The authors investigated in this study the effects of two electronic notes conditions (complete vs. partial) and two testing conditions (immediate vs. delayed) on three types of tests (fact, structure, and application). A 2 x 2 factorial multivariate analysis of variance (MANOVA) yielded no significant main effects for notes conditions on the fact…

  1. Benefits of an Electronic Consultation-Liaison Note System: Better Notes Faster

    ERIC Educational Resources Information Center

    Sola, Christopher L.; Bostwick, J. Michael; Sampson, Shirlene

    2007-01-01

    Objective: The authors determined the efficiency of electronic documentation in consultation-liaison psychiatry. METHOD: An electronic note system was customized for a psychiatric consultation note. Specific attention given to common diagnoses permitted rapid documentation. Results: Residents learned the system quickly. The standardized nature of…

  2. A Comparison of Suicide Note Writers with Suicides Who Did Not Leave Notes

    ERIC Educational Resources Information Center

    Callanan, Valerie J.; Davis, Mark S.

    2009-01-01

    There is disagreement in the suicide literature on the value of suicide notes as a data source, particularly regarding the extent to which suicide decedents who write notes differ from those who do not. Using 10 years of suicide cases from Summit County, Ohio, these two groups were compared on 40 variables including sociodemographic…

  3. European Scientific Notes. Volume 37, Number 6.

    DTIC Science & Technology

    1983-06-30

    AD-A31 850 EUROPEAN SlN11I NOTE VOUM 37 NUMBRbU OFIC 1/ OF NAVAL RESEARCH LONDON (ENGLAND) D MOSHER ET AL. 30 JUN 83 ESN-37-6 UNLASSIFIED F/G 5/2 NIL... RESEARCH LONDON EUROPEAN SCIENTIFIC NOTES ESN 37-6 30 JUNE 1983 V OF Distributed by the Office of Naval Research Branch Office. C This document is issued...PROJECT TASK US Office of Naval Research , Branch Office London Box 39 FPO NY 09510 II. CONTROLLING OFFICE NAME AND ADDRESS 12. REPORT DATE 30 aune

  4. A Note About HARP's State Trimming Method

    NASA Technical Reports Server (NTRS)

    Butler, Ricky W.; Hayhurst, Kelly J.; Johnson, Sally C.

    1998-01-01

    This short note provides some additional insight into how the HARP program works. In some cases, it is possible for HARP to tdm away too many states and obtain an optimistic result. The HARP Version 7.0 manual warns the user that 'Unlike the ALL model, the SAME model can automatically drop failure modes for certain system models. The user is cautioned to insure that no important failure modes are dropped; otherwise, a non-conservative result can be given.' This note provides an example of where this occurs and a pointer to further documentation that gives a means of bounding the error associated with trimming these states.

  5. Xyce parallel electronic simulator release notes.

    SciTech Connect

    Keiter, Eric R; Hoekstra, Robert John; Mei, Ting; Russo, Thomas V.; Schiek, Richard Louis; Thornquist, Heidi K.; Rankin, Eric Lamont; Coffey, Todd S; Pawlowski, Roger P; Santarelli, Keith R.

    2010-05-01

    The Xyce Parallel Electronic Simulator has been written to support, in a rigorous manner, the simulation needs of the Sandia National Laboratories electrical designers. Specific requirements include, among others, the ability to solve extremely large circuit problems by supporting large-scale parallel computing platforms, improved numerical performance and object-oriented code design and implementation. The Xyce release notes describe: Hardware and software requirements New features and enhancements Any defects fixed since the last release Current known defects and defect workarounds For up-to-date information not available at the time these notes were produced, please visit the Xyce web page at http://www.cs.sandia.gov/xyce.

  6. Application Note: Power Grid Modeling With Xyce.

    SciTech Connect

    Sholander, Peter E.

    2015-06-01

    This application note describes how to model steady-state power flows and transient events in electric power grids with the SPICE-compatible Xyce TM Parallel Electronic Simulator developed at Sandia National Labs. This application notes provides a brief tutorial on the basic devices (branches, bus shunts, transformers and generators) found in power grids. The focus is on the features supported and assumptions made by the Xyce models for power grid elements. It then provides a detailed explanation, including working Xyce netlists, for simulating some simple power grid examples such as the IEEE 14-bus test case.

  7. Surgical variation of microvascular decompression for trigeminal neuralgia: A technical note and anatomical study

    PubMed Central

    da Silva, Otávio T.; de Almeida, César C.; Iglesio, Ricardo F.; de Navarro, Jessie M.; Teixeira, Manoel J.; Duarte, Kleber P.

    2016-01-01

    Background: In this article, the authors described their experience in microvascular decompression for trigeminal neuralgia. Methods: The microvascular decompression technique used in the authors’ institution is described in a step by step manner with some illustrative cases as well as a cadaver dissection to highlight the differences with other previously described techniques. Results: Since 2013, 107 patients were operated in the Neurosurgery Division of the University of São Paulo using the described technique, with a shorter operative time and avoiding cerebellar retractor compared with classic techniques. Conclusion: Our modified microvascular decompression technique for trigeminal neuralgia can be used with safety and efficiency for treating trigeminal neuralgia. PMID:27625893

  8. Disk Diffusion Assay to Assess the Antimicrobial Activity of Marine Algal Extracts.

    PubMed

    Desbois, Andrew P; Smith, Valerie J

    2015-01-01

    Marine algae are a relatively untapped source of bioactive natural products, including those with antimicrobial activities. The ability to assess the antimicrobial activity of cell extracts derived from algal cultures is vital to identifying species that may produce useful novel antibiotics. One assay that is used widely for this purpose is the disk diffusion assay due to its simplicity, rapidity, and low cost. Moreover, this assay gives output data that are easy to interpret and can be used to screen many samples at once irrespective of the solvent used during preparation. In this chapter, a step-by-step protocol for performing a disk diffusion assay is described. The assay is particularly well suited to testing algal cell extracts and fractions resulting from separation through bioassay-guided approaches.

  9. Notes & Reflections. Issue 7, Fall 2004

    ERIC Educational Resources Information Center

    Fitzpatrick, Michele, Ed.

    2004-01-01

    "Notes & Reflections" offers practical information--ideas, strategies, tools, and resources--about topics of special interest to professional developers who are working to improve school performance. Today, professional development services to schools are provided by variety of people: teacher leaders; principals; and district, regional, and state…

  10. A note on the Goodman Jack

    USGS Publications Warehouse

    Swolfs, H.S.; Kibler, J.D.

    1982-01-01

    A Note on the Goodman Jack: Reconnaissance experiments, performed to evaluate the practical utility of the hard-rock variety of the Goodman Jack, reveal that the Hustrulid-T* correction adequately reconciles the discrepancy between the measured and true deformation modulus of the rock mass in the range of 30 to 50 gigapascals. ?? 1982 Springer-Verlag.

  11. Practice Notes: Strategies in Health Education

    ERIC Educational Resources Information Center

    Health Education & Behavior, 2007

    2007-01-01

    The Practice Notes section is intended to keep readers informed about health education practice around the country. It is an attempt to spread the word about exemplary strategies, initiatives, and programs and share successes in overcoming obstacles or challenges. Periodically, articles presenting perspectives on practice-related issues are also…

  12. Note Taking in Multi-Media Settings

    ERIC Educational Resources Information Center

    Black, Kelly; Yao, Guangming

    2014-01-01

    We provide a preliminary exploration into the use of note taking when combined with video examples. Student volunteers were divided into three groups and asked to perform two problems. The first problem was explored in a classroom setting and the other problem was a novel problem. The students were asked to complete the two questions. Furthermore,…

  13. Shooting Gallery Notes. Working Paper #22. Preliminary.

    ERIC Educational Resources Information Center

    Bourgois, Philippe

    This paper contains ethnographic participant-observation field notes taken on a one-night visit to a "shooting gallery" in East Harlem (New York City) along with background information and commentary. East Harlem, also referred to as "El Barrio" or Spanish Harlem, is a 200-square block neighborhood on the upper East Side of…

  14. New Wrinkles on Retirement: Program Notes.

    ERIC Educational Resources Information Center

    Wray, Robert P.; Thorson, James A.

    The program notes were prepared to accompany the television series "New Wrinkles on Retirement." The eight units in the series are: facing inflation, which covers the decreasing value of the dollar, transportation costs, medical expenses, cutting expenses, family budgeting, investments, and places to live; vigor regained, which covers exercise and…

  15. Practice Notes: Strategies in Health Education

    ERIC Educational Resources Information Center

    Health Education & Behavior, 2007

    2007-01-01

    This article is included in the Practice Notes section of this journal, which is intended to keep readers informed about health education practice around the country. It is an attempt to spread the word about exemplary strategies, initiatives, and programs and share successes in overcoming obstacles or challenges. In this article, two programs are…

  16. Building Simple Hidden Markov Models. Classroom Notes

    ERIC Educational Resources Information Center

    Ching, Wai-Ki; Ng, Michael K.

    2004-01-01

    Hidden Markov models (HMMs) are widely used in bioinformatics, speech recognition and many other areas. This note presents HMMs via the framework of classical Markov chain models. A simple example is given to illustrate the model. An estimation method for the transition probabilities of the hidden states is also discussed.

  17. College Success Course, Fall 1988. Research Note.

    ERIC Educational Resources Information Center

    Reis, Elizabeth

    In spring 1988, Moraine Valley Community College (MVCC), in Palos Hills, Illinois, implemented "College Success," a course to increase student academic performance and improve college retention. Students in the course learned a variety of techniques to help them succeed in college, including note-taking skills, time management, memory…

  18. Practice Notes: Strategies in Health Education

    ERIC Educational Resources Information Center

    Health Education & Behavior, 2009

    2009-01-01

    The "Practice Notes" section is intended to keep readers informed about health education practice around the country. It is an attempt to spread the word about exemplary strategies, initiatives, and programs and share successes in overcoming obstacles or challenges. This article features two new programs on health education: (1) Project FIESTA;…

  19. A Note on Evaluating Supplemental Instruction

    ERIC Educational Resources Information Center

    Paloyo, Alfredo R.

    2015-01-01

    Selection bias pervades the evaluation of supplemental instruction (SI) in non-experimental settings. This brief note provides a formal framework to understand this issue. The objective is to contribute to the accumulation of credible evidence on the impact of SI.

  20. 7 CFR 1735.41 - Notes.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 11 2013-01-01 2013-01-01 false Notes. 1735.41 Section 1735.41 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GENERAL POLICIES, TYPES OF LOANS, LOAN REQUIREMENTS-TELECOMMUNICATIONS PROGRAM Terms of Loans §...

  1. 7 CFR 1735.41 - Notes.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 11 2014-01-01 2014-01-01 false Notes. 1735.41 Section 1735.41 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GENERAL POLICIES, TYPES OF LOANS, LOAN REQUIREMENTS-TELECOMMUNICATIONS PROGRAM Terms of Loans §...

  2. 7 CFR 1735.41 - Notes.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 11 2011-01-01 2011-01-01 false Notes. 1735.41 Section 1735.41 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GENERAL POLICIES, TYPES OF LOANS, LOAN REQUIREMENTS-TELECOMMUNICATIONS PROGRAM Terms of Loans §...

  3. 7 CFR 1735.41 - Notes.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 11 2012-01-01 2012-01-01 false Notes. 1735.41 Section 1735.41 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GENERAL POLICIES, TYPES OF LOANS, LOAN REQUIREMENTS-TELECOMMUNICATIONS PROGRAM Terms of Loans §...

  4. 7 CFR 1735.41 - Notes.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Notes. 1735.41 Section 1735.41 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GENERAL POLICIES, TYPES OF LOANS, LOAN REQUIREMENTS-TELECOMMUNICATIONS PROGRAM Terms of Loans §...

  5. 38 CFR 21.4504 - Promissory note.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Promissory note. 21.4504 Section 21.4504 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED... liability of such person for an educational loan shall be discharged. (f) Fraud. Material...

  6. A Note on Morley's Triangle Theorem

    ERIC Educational Resources Information Center

    Mueller, Nancy; Tikoo, Mohan; Wang, Haohao

    2012-01-01

    In this note, we offer a proof of a variant of Morley's triangle theorem, when the exterior angles of a triangle are trisected. We also offer a generalization of Morley's theorem when angles of an "n"-gon are "n"-sected. (Contains 9 figures.)

  7. A Taste of Sunrise: A Director's Notes.

    ERIC Educational Resources Information Center

    Hovasse, Nancy

    2001-01-01

    Describes a director's experience working with "A Taste of Sunrise," a play depicting the deaf culture. Stresses how important it is to educate the cast and provide them an opportunity to learn sign language. Notes that American Sign Language is complex and beautiful and deserves to be carefully studied and respectfully acknowledged by the hearing…

  8. Science Notes: Dilution of a Weak Acid

    ERIC Educational Resources Information Center

    Talbot, Christopher; Wai, Chooi Khee

    2014-01-01

    This "Science note" arose out of practical work involving the dilution of ethanoic acid, the measurement of the pH of the diluted solutions and calculation of the acid dissociation constant, K[subscript a], for each diluted solution. The students expected the calculated values of K[subscript a] to be constant but they found that the…

  9. GeoMapApp Learning Activities: A Virtual Lab Environment for Student-Centred Engagement with Geoscience Data

    NASA Astrophysics Data System (ADS)

    Kluge, S.; Goodwillie, A. M.

    2012-12-01

    As STEM learning requirements enter the mainstream, there is benefit to providing the tools necessary for students to engage with research-quality geoscience data in a cutting-edge, easy-to-use map-based interface. Funded with an NSF GeoEd award, GeoMapApp Learning Activities ( http://serc.carleton.edu/geomapapp/collection.html ) are being created to help in that endeavour. GeoMapApp Learning Activities offer step-by-step instructions within a guided inquiry approach that enables students to dictate the pace of learning. Based upon GeoMapApp (http://www.geomapapp.org), a free, easy-to-use map-based data exploration and visualisation tool, each activity furnishes the educator with an efficient package of downloadable documents. This includes step-by-step student instructions and answer sheet; an educator's annotated worksheet containing teaching tips, additional content and suggestions for further work; and, quizzes for use before and after the activity to assess learning. Examples of activities so far created involve calculation and analysis of the rate of seafloor spreading; compilation of present-day evidence for huge ancient landslides on the seafloor around the Hawaiian islands; a study of radiometrically-dated volcanic rocks to help understand the concept of hotspots; and, the optimisation of contours as a means to aid visualisation of 3-D data sets on a computer screen. The activities are designed for students at the introductory undergraduate, community college and high school levels, and present a virtual lab-like environment to expose students to content and concepts typically found in those educational settings. The activities can be used in the classroom or out of class, and their guided nature means that the requirement for teacher intervention is reduced thus allowing students to spend more time analysing and understanding geoscience data, content and concepts. Each activity is freely available through the SERC-Carleton web site.

  10. Technical note: Coordination and harmonization of the multi-scale, multi-model activities HTAP2, AQMEII3, and MICS-Asia3: simulations, emission inventories, boundary conditions, and model output formats

    NASA Astrophysics Data System (ADS)

    Galmarini, Stefano; Koffi, Brigitte; Solazzo, Efisio; Keating, Terry; Hogrefe, Christian; Schulz, Michael; Benedictow, Anna; Griesfeller, Jan Jurgen; Janssens-Maenhout, Greet; Carmichael, Greg; Fu, Joshua; Dentener, Frank

    2017-01-01

    We present an overview of the coordinated global numerical modelling experiments performed during 2012-2016 by the Task Force on Hemispheric Transport of Air Pollution (TF HTAP), the regional experiments by the Air Quality Model Evaluation International Initiative (AQMEII) over Europe and North America, and the Model Intercomparison Study for Asia (MICS-Asia). To improve model estimates of the impacts of intercontinental transport of air pollution on climate, ecosystems, and human health and to answer a set of policy-relevant questions, these three initiatives performed emission perturbation modelling experiments consistent across the global, hemispheric, and continental/regional scales. In all three initiatives, model results are extensively compared against monitoring data for a range of variables (meteorological, trace gas concentrations, and aerosol mass and composition) from different measurement platforms (ground measurements, vertical profiles, airborne measurements) collected from a number of sources. Approximately 10 to 25 modelling groups have contributed to each initiative, and model results have been managed centrally through three data hubs maintained by each initiative. Given the organizational complexity of bringing together these three initiatives to address a common set of policy-relevant questions, this publication provides the motivation for the modelling activity, the rationale for specific choices made in the model experiments, and an overview of the organizational structures for both the modelling and the measurements used and analysed in a number of modelling studies in this special issue.

  11. 42 CFR 57.308 - Nursing student loan promissory note.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Nursing student loan promissory note. 57.308... Nursing Student Loans § 57.308 Nursing student loan promissory note. (a) Promissory note form. Each nursing student loan must be evidenced by a properly executed promissory note in a form approved by...

  12. 42 CFR 57.308 - Nursing student loan promissory note.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Nursing student loan promissory note. 57.308... Nursing Student Loans § 57.308 Nursing student loan promissory note. (a) Promissory note form. Each nursing student loan must be evidenced by a properly executed promissory note in a form approved by...

  13. 42 CFR 57.308 - Nursing student loan promissory note.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Nursing student loan promissory note. 57.308... Nursing Student Loans § 57.308 Nursing student loan promissory note. (a) Promissory note form. Each nursing student loan must be evidenced by a properly executed promissory note in a form approved by...

  14. 42 CFR 57.308 - Nursing student loan promissory note.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Nursing student loan promissory note. 57.308... Nursing Student Loans § 57.308 Nursing student loan promissory note. (a) Promissory note form. Each nursing student loan must be evidenced by a properly executed promissory note in a form approved by...

  15. 42 CFR 57.308 - Nursing student loan promissory note.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Nursing student loan promissory note. 57.308... Nursing Student Loans § 57.308 Nursing student loan promissory note. (a) Promissory note form. Each nursing student loan must be evidenced by a properly executed promissory note in a form approved by...

  16. Thinking Strategically to Record Notes in Content Classes

    ERIC Educational Resources Information Center

    Boyle, Joseph R.

    2011-01-01

    Although teachers today use a variety of teaching methods in content-area classrooms, lecture learning and note-taking still comprise a considerable portion of time in these classes. Unfortunately, most students are poor note-takers, typically recording only about one quarter of lecture notes. Strategic note-taking was developed to assist students…

  17. DigiMemo: Facilitating the Note Taking Process

    ERIC Educational Resources Information Center

    Kurt, Serhat

    2009-01-01

    Everyone takes notes daily for various reasons. Note taking is very popular in school settings and generally recognized as an effective learning strategy. Further, note taking is a complex process because it requires understanding, selection of information and writing. Some new technological tools may facilitate the note taking process. Among such…

  18. Active filter application guide. Final report

    SciTech Connect

    Not Available

    1998-01-01

    Nonlinear loads interacting with a utility can cause harmonic currents and voltages. Nonlinear loads include arcing loads, power converters that use switching devices, and saturable transformers and reactors. When reactive loads interact with harmonic sources, the results can be harmonic distortion, malfunction of harmonic sensitive equipment, and capacitor overload. To solve these harmonic disturbances, most passive harmonic filters must be custom designed to operate with site-specific conditions. Active filters, on the other hand, offer the potential of a single black-box solution that is relatively independent of system parameters. Power quality problems attributable to harmonic voltages and currents are increasing. Traditionally, passive harmonic filters have been used to solve these problems. A more recent approach for harmonic compensation uses active filters. The Active Filter Application Guide covers fundamentals of harmonics, discusses harmonic producing loads, presents harmonic filtering principles (both active and passive), and provides a step-by-step application guide for analyzing and specifying an active filter. Also included in the Guide are two active-filter case studies. Each demonstrates how the application guide can be used to select and specify solutions for both single harmonic load and multiple harmonic producing loads at a clustered site.

  19. NOTE: The specific uptake size index for quantifying radiopharmaceutical uptake

    NASA Astrophysics Data System (ADS)

    Fleming, John S.; Bolt, Livia; Stratford, Jennifer S.; Kemp, Paul M.

    2004-07-01

    Quantitative indices of radionuclide uptake in an object of interest provide a useful adjunct to qualitative interpretation in the diagnostic application of radionuclide imaging. This note describes a new measure of total uptake of an organ, the specific uptake size index (SUSI). It can either be related in absolute terms to the total activity injected or to the specific activity in a reference region. As it depends on the total activity in the object, the value obtained will not depend on the resolution of the imaging process, as is the case with some other similar quantitative indices. This has been demonstrated in an experiment using simulated images. The application of the index to quantification of dopamine receptor SPECT imaging and parathyroid thyroid subtraction planar scintigraphy is described. The index is considered to be of potential value in reducing variation in quantitative assessment of uptake in objects with applications in all areas of radionuclide imaging.

  20. 15 CFR Notes Applicable to State... - Notes applicable to State of Understanding related to Medical Equipment:

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the practice of medicine (does not include medical research). (2) Commodities or software are... Understanding related to Medical Equipment: applicable Notes applicable to State of Understanding related to Medical Equipment: Commerce and Foreign Trade Regulations Relating to Commerce and Foreign...

  1. Constructing MnO{sub 2}/single crystalline ZnO nanorod hybrids with enhanced photocatalytic and antibacterial activity

    SciTech Connect

    Yu, Weiwei; Liu, Tiangui; Cao, Shiyi; Wang, Chen; Chen, Chuansheng

    2016-07-15

    In order to improve the photocatalytic and antibacterial activity of ZnO nanorods, ZnO nanorods decorated with MnO{sub 2} nanoparticles (MnO{sub 2}/ZnO nanorod hybrids) were prepared by using microwave assisted coprecipitation method under the influence of hydrogen peroxide, and the structure, photocatalytic activity and antibacterial property of the products were studied. Experimental results indicated that MnO{sub 2} nanoparticles are decorated on the surface of single crystalline ZnO nanorods. Moreover, the resultant MnO{sub 2}/ZnO nanorod hybrids have been proven to possess good photocatalytic and antibacterial activity, which their degradated efficiency for Rhodamin B (RhB) is twice as the pure ZnO nanorods. Enhancement for photocatalytic and antibacterial activity is mainly attributed to the low band gap energy and excellent electrochemical properties of MnO{sub 2} nanoparticles. - Graphical abstract: The MnO{sub 2}/single crystalline ZnO nanorods hybrids, which MnO{sub 2} nanoparticles are loaded on the surface of ZnO nanorods, were prepared by the step-by-step precipitation method under the assistance of ammonia and hydrogen peroxide. Display Omitted - Highlights: • MnO{sub 2}/ZnO nanorod hybrids were prepared by the step-by-step assembly method. • Single crystalline ZnO nanorods can be decorated by MnO{sub 2} nanoparticles. • MnO{sub 2}/ZnO nanorod hybrids possess good photocatalytic and antibacterial activity. • MnO{sub 2} can improve the photocatalytic activity of ZnO nanorods under visible light.

  2. LLW notes, Vol. 11, No. 2

    SciTech Connect

    1996-03-01

    `LLW Notes` is distributed by Afton Associates, Inc. to Low-Level Radioactive Waste Forum Participants and other state, and compact officials identified by those Participants to receive LLW Notes. The Low-Level Radioactive Waste Forum (LLW Forum) is an association of state and compact representatives, appointed by governors and compact commissions, established to facilitate state and compact implementation of the Low-Level Radioactive Waste Policy Act of 1980 and the Low-Level Radioactive Waste Policy amendments Act of 1985 and to promote the objectives of low-level radioactive waste regional compacts. The LLW Forum provides an opportunity for state and compact officials to share information with one another and to exchange views with officials of federal agencies and other interested parties.

  3. LLW notes. Vol. 11, No. 1

    SciTech Connect

    1996-02-01

    `LLW Notes` is distributed by Afton Associates, Inc. to Low-Level Radioactive Waste Forum Participants and other state and compact officials identified by those Participants to receive `LLW Notes`. The Low-Level Radioactive Waste Forum (LLW Forum) is an association of state and compact representatives, appointed by governors and compact commissions, established to facilitate state and compact implementation of the Low-Level Radioactive Waste Policy Act of 1980 and the Low-Level Radioactive Waste Policy Amendments Act of 1985 and to promote the objectives of low-level radioactive waste regional compacts. The LLW Forum provides an opportunity for state and compact officials to share information with one another and to exchange views with officials of federal agencies and other interested parties.

  4. LLW notes. Volume 11, No.8

    SciTech Connect

    1996-12-01

    `LLW Notes` is distributed by Afton Associates, Inc. to Low-Level Radioactive Waste Forum Participants and other state, and compact officials identified by those Participants to receive `LLW Notes`. The Low-Level Radioactive Waste Forum (LLW Forum) is an association of state and compact representatives, appointed by governors and compact commissions, established to facilitate state and compact implementation of the Low-Level Radioactive Waste Policy Act of 1980 and the Low-Level Radioactive Waste Policy Amendments Act of 1985 and to promote the objectives of low-level radioactive waste regional compacts. The LLW Forum provides an opportunity for state and compact officials to share information with one another and to exchange views with officials of federal agencies and other interested parties.

  5. European Scientific Notes. Volume 36, Number 5,

    DTIC Science & Technology

    1982-05-31

    OF TIS PAG9 (OWN -WO 9010" . - erospace Research and Development and the United States Army Research and Standardization Group . Articles are also...solid-state physics group . J. R. Neighbours 117 PM & NOTES News 117 ONR Cosponsored Conferences 120 ONRL Visiting Scientist Program 120A ’. ESN 36-5...one imag - ines, gigantic data banks available, and the (1) Commitment at executive level material in them could be converted into ac- to systematize

  6. European Scientific Notes. Volume 36, Number 4,

    DTIC Science & Technology

    1982-04-30

    primarily for the information of L ’ S. Government scientific personnel and contractors. It i-, not coli- c sidered part of the scientific literature...Stjbtiti.) S YEO EOT&PRO OEE EUROPEAN SCIENTIFIC NOTES April_____________ S. PERFORMING ORG. REPORT NUMBER 7. AUTHOR(*) S. CONTRACT OR GRANT NUMBER(#) 9... PERFORMING ORGANI1ZATION NAME AND ADDRESS 10, PROGRAM ELEMENT PROJECT, TASK( AREA & WORK UNIT NUMBERS US OFFICE OF NAVAL RESEARCH BRANCH OFFICE

  7. European Scientific Notes. Volume 34, Number 10,

    DTIC Science & Technology

    1980-10-31

    Spectroscopy in Solids, A Discussion Meeting of the Royal Society A.N. Garroway 496 Some Solid State Physics in Birmingham J.R. Neighbours ’ ~ INEWS AND NOTES... Garroway (NRL, Washington, about June 1981 in the Proceedings of DC) suggested that presently achieved the Royal Society (London). This written...solid- tnributions of isotropic chemical shifts state NMR. (A.N. Garroway , Chemistry within the specimen, and no improvement Division, Naval Research

  8. European Scientific Notes. Volume 34, Number 4,

    DTIC Science & Technology

    1980-04-30

    probed, or as relativistic components may help resolve the remaining dis- of the nucleus ’ mcmentum distribution crepancies. For large momentum trans...RESOLUTION TST CHART OFFICE OF NAVAL RESEARCH LONDON COLEYEL> EUROPEAN SCIENTIFIC NOTES 0 ESN 34-4+ 30 April 1980 DTlC ELECTE Distributed by the Office...contractors. It is not con- sidered part of the scientific literature and should not be. cited : APPROVED FOR PUBLIC RELEASE: DISTRIBUTION UNLIMITED 80 6

  9. Sound decay of notes from acoustic guitars

    NASA Astrophysics Data System (ADS)

    Galazen, Erika; Nordberg, Joni; Huber, Thomas M.

    2005-09-01

    The acoustic guitar produces tones by transferring energy from the strings, through the bridge to the top plate, back, and air cavity of the guitar. The vibrations are ultimately radiated into the air as sound. The air-cavity and body resonances of the guitar play an important role in both the tone and the sustain (the time it takes notes to decay) produced by the guitar. To study the relationship between resonances of the guitar and the sustain of notes, the resonance frequencies were measured using a mechanical shaker attached to the body of the guitar and laser Doppler vibrometer to measure its vibration. A string was tuned to different frequencies and plucked. The decay of the note was measured with an electromagnetic pickup that measured the vibration of the string, a vibrometer to measure vibration of the top plate, and microphones located inside and outside the guitar. As expected, when the fundamental frequency of the string was near one of the resonances of the guitar, the decay rate was faster (shorter sustain) than when the string was between resonances. The relationship between the decay rates of the different parts of the system will also be discussed.

  10. Technical note: Monitoring grazing bites and walking activity with pedometers.

    PubMed

    Umemura, K

    2013-02-01

    Three types of pedometers installed on loosely fitted neck collars were investigated to determine the accuracy with which the devices measured the number of grazing bites performed by cows. The pedometer memory stored the summed number of bites over 1-h intervals for up to 10d, and the battery had a life of more than 3 mo. The values recorded by the pedometers were linearly related to the number of bites measured by visual observation and were unaffected by rumination. The correlation coefficients between the pedometer values and the number of bites were all >0.9. Circadian and day-to-day variations in the number of grazing bites were obtained by all 3 pedometers. The regression coefficients differed among the pedometers. The pedometers also responded to the occurrence of walking steps. The values recorded by the pedometers were linearly related to the observed number of walking steps. The correlation coefficients between the pedometer values and the number of steps were all >0.9. Although the number of walking steps affected the number of grazing bites, the number of bites greatly exceeded the number of walking steps. One type of pedometer, equipped with a 2-dimensional accelerometer, was used to analyze both grazing and walking behaviors. The back-forth and right-left movements of the pedometer had similar values during walking, whereas the values of the back-forth movements were greater during grazing. I conclude that pedometers can be used to measure the number of grazing bites but that this technique requires calibration to relate the pedometer values to the number of grazing bites. Observations of the back-forth and right-left movements of pedometers on neck collars will aid in distinguishing the grazing and walking behaviors of cows.

  11. Generation of GFP Reporter Human Induced Pluripotent Stem Cells Using AAVS1 Safe Harbor Transcription Activator-Like Effector Nuclease.

    PubMed

    Luo, Yongquan; Rao, Mahendra; Zou, Jizhong

    2014-05-16

    Generation of a fluorescent GFP reporter line in human induced pluripotent stem cells (hiPSCs) provides enormous potentials in both basic stem cell research and regenerative medicine. A protocol for efficiently generating such an engineered reporter line by gene targeting is highly desired. Transcription activator-like effector nucleases (TALENs) are a new class of artificial restriction enzymes that have been shown to significantly promote homologous recombination by >1000-fold. The AAVS1 (adeno-associated virus integration site 1) locus is a "safe harbor" and has an open chromatin structure that allows insertion and stable expression of transgene. Here, we describe a step-by-step protocol from determination of TALENs activity, hiPSC culture, and delivery of a donor into AAVS1 targeting site, to validation of targeted integration by PCR and Southern blot analysis using hiPSC line, and a pair of open-source AAVS1 TALENs.

  12. The Composer’s Program Note for Newly Written Classical Music: Content and Intentions

    PubMed Central

    Blom, Diana M.; Bennett, Dawn; Stevenson, Ian

    2016-01-01

    In concerts of western classical music the provision of a program note is a widespread practice dating back to the 18th century and still commonly in use. Program notes tend to inform listeners and performers about historical context, composer biographical details, and compositional thinking. However, the scant program note research conducted to date reveals that program notes may not foster understanding or enhance listener enjoyment as previously assumed. In the case of canonic works, performers and listeners may already be familiar with much of the program note information. This is not so in the case of newly composed works, which formed the basis of the exploratory study reported here. This article reports the views of 17 living contemporary composers on their writing of program notes for their own works. In particular, the study sought to understand the intended recipient, role and the content of composer-written program notes. Participating composers identified three main roles for their program notes: to shape a performer’s interpretation of the work; to guide, engage or direct the listener and/or performer; and as collaborative mode of communication between the composer, performer, and listener. For some composers, this collaboration was intended to result in “performative listening” in which listeners were actively engaged in bringing each composition to life. This was also described as a form of empathy that results in the co-construction of the musical experience. Overall, composers avoided giving too much personal information and they provided performers with more structural information. However, composers did not agree on whether the same information should be provided to both performers and listeners. Composers’ responses problematize the view of a program note as a simple statement from writer to recipient, indicating instead a more complex set of relations at play between composer, performer, listener, and the work itself. These relations

  13. The Composer's Program Note for Newly Written Classical Music: Content and Intentions.

    PubMed

    Blom, Diana M; Bennett, Dawn; Stevenson, Ian

    2016-01-01

    In concerts of western classical music the provision of a program note is a widespread practice dating back to the 18th century and still commonly in use. Program notes tend to inform listeners and performers about historical context, composer biographical details, and compositional thinking. However, the scant program note research conducted to date reveals that program notes may not foster understanding or enhance listener enjoyment as previously assumed. In the case of canonic works, performers and listeners may already be familiar with much of the program note information. This is not so in the case of newly composed works, which formed the basis of the exploratory study reported here. This article reports the views of 17 living contemporary composers on their writing of program notes for their own works. In particular, the study sought to understand the intended recipient, role and the content of composer-written program notes. Participating composers identified three main roles for their program notes: to shape a performer's interpretation of the work; to guide, engage or direct the listener and/or performer; and as collaborative mode of communication between the composer, performer, and listener. For some composers, this collaboration was intended to result in "performative listening" in which listeners were actively engaged in bringing each composition to life. This was also described as a form of empathy that results in the co-construction of the musical experience. Overall, composers avoided giving too much personal information and they provided performers with more structural information. However, composers did not agree on whether the same information should be provided to both performers and listeners. Composers' responses problematize the view of a program note as a simple statement from writer to recipient, indicating instead a more complex set of relations at play between composer, performer, listener, and the work itself. These relations are

  14. Radial access for cerebrovascular procedures: Case report and technical note

    PubMed Central

    Vance, Ansar Z; Sivapatham, Thinesh

    2015-01-01

    Background Advantages of radial access over brachial/axillary or femoral access have been well described for several decades and include decreased cost, patient preference, and decreased major access site complications. Despite these advantages, radial access is rarely employed or even considered for neurointerventional procedures. This attitude should be reconsidered given several recent large, randomized, controlled trials from the cardiovascular literature proving that radial access is associated with statistically lower costs, decreased incidence of myocardial infarctions, strokes, and even decreased mortality. Radial access is now considered the standard of care for percutaneous coronary interventions in most US centers. Although radial access has been described for neurovascular procedures in the past, overall experience is limited. The two major challenges are the unique anatomy required to access the cerebral vasculature given very acute angles between the arm and craniocervical vessels and limitations in available technology. Methods We present a simplified approach to radial access for cerebrovascular procedures and provide a concise step-by-step approach for patient selection, ultrasound-guided single-wall access, recommended catheters/wires, and review of patent hemostasis. Additionally, we present a complex cerebrovascular intervention in which standard femoral access was unsuccessful, while radial access was quickly achieved to highlight the importance of familiarity with the radial approach for all neurointerventionalists. Results We have found that the learning curve is not too steep and that the radial access approach can be adopted smoothly for a large percentage of diagnostic and interventional neuroradiologic procedures. Conclusions Radial access should be considered in all patients undergoing a cerebrovascular procedure. PMID:26659807

  15. Niobium-silica catalysts for the selective epoxidation of cyclic alkenes: the generation of the active site by grafting niobocene dichloride.

    PubMed

    Tiozzo, Cristina; Bisio, Chiara; Carniato, Fabio; Gallo, Alessandro; Scott, Susannah L; Psaro, Rinaldo; Guidotti, Matteo

    2013-08-28

    Niobium-containing silica materials obtained by deposition via liquid-phase grafting or dry impregnation of niobocene(iv) dichloride are active and selective catalysts in the epoxidation of alkenes in the presence of aqueous hydrogen peroxide. The generation of the catalytically-active Nb species was followed step-by-step, and investigated using a combined DR-UV-Vis, NIR, Raman, XRD, XANES and EXAFS analyses. At the end of the grafting procedure, the nature of the surface active species can be described as an oxo-Nb(v) site, tripodally grafted onto the silica surface in close proximity to other Nb(v) centres. The liquid-phase methodology provides a better dispersion of the metal sites onto the siliceous support than the dry-impregnation approach. The niobium-silica catalysts were then tested in the epoxidation of cyclohexene and 1-methylcyclohexene, as model substrates.

  16. Notes for Brazil sampling frame evaluation trip

    NASA Technical Reports Server (NTRS)

    Horvath, R. (Principal Investigator); Hicks, D. R. (Compiler)

    1981-01-01

    Field notes describing a trip conducted in Brazil are presented. This trip was conducted for the purpose of evaluating a sample frame developed using LANDSAT full frame images by the USDA Economic and Statistics Service for the eventual purpose of cropland production estimation with LANDSAT by the Foreign Commodity Production Forecasting Project of the AgRISTARS program. Six areas were analyzed on the basis of land use, crop land in corn and soybean, field size and soil type. The analysis indicated generally successful use of LANDSAT images for purposes of remote large area land use stratification.

  17. A Note on Validity Generalization Procedures.

    DTIC Science & Technology

    1985-01-01

    RD-fl15 865 A NOTE ON VALIDITY GENERALIZATION PROCEDURES(U) GEORGIA i/i INST OF TECH ATLANTA SCHOOL OF PSYCHOLOGY L R JANES ET AL. JAN 85 GT-ONR-7...models for validities and validity distributions. Ř Validity Generalization 36 References Blum, M.L. & Naylor, J.C. (1968) Industrial Psychology ... Psychological Review, 80, 307-336. Burke, M.J. (1984) Validity generalization : A review and critique of the correlation model. Personnel Psychology , 37, 93-113

  18. European Scientific Notes. Volume 38, Number 5.

    DTIC Science & Technology

    1984-05-01

    1984) Spe!ia, Italy, is sponsoring an interna- Astrophysics 2; (3) Hard Hadron Colli- tional symposium called "The Silent sions, 1; (4) e+e- Collisions ...NOTES ESN 38-5 May 1984 I -A r- IONOO0 C-3 LUJ Distributed by the Office of Naval Research Branch Office. dz London This document is issued primarily...be cited as such. APPROVED FOR PUBLIC RELEAS&.: DISTRIBUTION UNLIMITED t 84 05 30 101 momI UNCLASSIFIED ECUPJ.ITY CLASSIFICATION OF THIS PAGE ( oen

  19. European Scientific Notes. Volume 34. Number 5,

    DTIC Science & Technology

    1980-05-31

    UNCLASSIFIED E SN-34-5 NL Ehhhhhhhhhommml Emomhhhmhhhhhhl OFFICE OF NAVAL RESEARCH LONDON EUROPEAN SCIENTIFIC NOTES ESN 34-5S 51 MAY 1980 Il *o Distributed by...Israeli Universities R.E. Machol 240 Operations Research in Italy- Part I R.E. Machol 245 IN E MThe Institute of Physics J.R. Neiahbours 250 Lasers...those of SRC’s Rutherford Laboratory The laboratory-environment studies at Chilton. Chilton is about 40. miles of nm-wave gaseous absorption have

  20. 7 CFR 1956.97 - Disposition of promissory notes.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...-Family Housing § 1956.97 Disposition of promissory notes. (a) Notes evidencing debts settled by...

  1. 111. AIR CONDENSATE PUMP. NOTE MAIN DISCHARGE HEADER ABOVE STEAMEND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    111. AIR CONDENSATE PUMP. NOTE MAIN DISCHARGE HEADER ABOVE STEAM-END CYLINDER. NOTE ALSO, THE 30' DISCHARGE VALVE AND ACTUATER TO THE LEFT OF THE PUMP. - Lakeview Pumping Station, Clarendon & Montrose Avenues, Chicago, Cook County, IL

  2. How college science students engage in note-taking strategies

    NASA Astrophysics Data System (ADS)

    Bonner, Janice M.; Holliday, William G.

    2006-10-01

    A composite theory of college science student note-taking strategies was derived from a periodic series of five interviews with 23 students and with other variables, including original and final versions of notes analyzed during a semester-long genetics course. This evolving composite theory was later compared with Van Meter, Yokoi, and Pressley's (Journal of Educational Psychology, 86, 323-338, 1994) corresponding composite college students' theory of note-taking. Students' notes in this long-term study were also compared with a standard of adequate note-taking established by experts. Analyses detected many similarities between the two composite theories. Analyses also provided evidence of inadequate note-taking strategies, inconsistencies between what students claimed and evidently did with their notes, and weak self-regulating learning strategies. Recommendations included prompting students during class on how to take notes.

  3. 22 CFR 230.09 - No acceleration of Eligible Notes.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... CONDITIONS § 230.09 No acceleration of Eligible Notes. Eligible Notes shall not be subject to acceleration, in whole or in part, by USAID, the Noteholder or any other party. USAID shall not have the right...

  4. A Pedagogic Cycle for EFL Note-Taking

    ERIC Educational Resources Information Center

    Siegel, Joseph

    2016-01-01

    More attention has been given to note-taking in EFL classrooms in recent years, probably due to growing numbers of EFL students who attend lectures given in English and the importance of note-taking during language proficiency tests. While textbooks and materials for note-taking practice are readily available, classroom techniques for teaching EFL…

  5. 29 CFR Appendices to Subpart L of... - Note

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 5 2013-07-01 2013-07-01 false Note Appendices to Subpart L of Part 1910 Labor Regulations... OCCUPATIONAL SAFETY AND HEALTH STANDARDS Fire Protection Pt. 1910, Subpt. L, Apps. Nt. Appendices to Subpart L of Part 1910—Note Note: The following appendices to subpart L, except appendix E, serve...

  6. 29 CFR Appendices to Subpart L of... - Note

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 5 2012-07-01 2012-07-01 false Note Appendices to Subpart L of Part 1910 Labor Regulations... OCCUPATIONAL SAFETY AND HEALTH STANDARDS Fire Protection Pt. 1910, Subpt. L, Apps. Nt. Appendices to Subpart L of Part 1910—Note Note: The following appendices to subpart L, except appendix E, serve...

  7. 29 CFR Appendices to Subpart L of... - Note

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 5 2011-07-01 2011-07-01 false Note Appendices to Subpart L of Part 1910 Labor Regulations... OCCUPATIONAL SAFETY AND HEALTH STANDARDS Fire Protection Pt. 1910, Subpt. L, Apps. Nt. Appendices to Subpart L of Part 1910—Note Note: The following appendices to subpart L, except appendix E, serve...

  8. 29 CFR Appendices to Subpart L of... - Note

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 5 2010-07-01 2010-07-01 false Note Appendices to Subpart L of Part 1910 Labor Regulations... OCCUPATIONAL SAFETY AND HEALTH STANDARDS Fire Protection Pt. 1910, Subpt. L, Apps. Nt. Appendices to Subpart L of Part 1910—Note Note: The following appendices to subpart L, except appendix E, serve...

  9. 29 CFR Appendices to Subpart L of... - Note

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 5 2014-07-01 2014-07-01 false Note Appendices to Subpart L of Part 1910 Labor Regulations... OCCUPATIONAL SAFETY AND HEALTH STANDARDS Fire Protection Pt. 1910, Subpt. L, Apps. Nt. Appendices to Subpart L of Part 1910—Note Note: The following appendices to subpart L, except appendix E, serve...

  10. 22 CFR 230.06 - Transferability of Guarantee; Note Register.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Transferability of Guarantee; Note Register... AND CONDITIONS § 230.06 Transferability of Guarantee; Note Register. A Noteholder may assign, transfer... on the date that the name of the new Noteholder is entered on the Note Register required to...

  11. 22 CFR 221.14 - Transferability of Guarantee; Note Register.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Transferability of Guarantee; Note Register... STANDARD TERMS AND CONDITIONS The Guarantee § 221.14 Transferability of Guarantee; Note Register. A... pledge shall be effective on the date that the name of the new Noteholder is entered on the Note...

  12. 22 CFR 221.14 - Transferability of Guarantee; Note Register.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Transferability of Guarantee; Note Register... STANDARD TERMS AND CONDITIONS The Guarantee § 221.14 Transferability of Guarantee; Note Register. A... pledge shall be effective on the date that the name of the new Noteholder is entered on the Note...

  13. 22 CFR 230.06 - Transferability of Guarantee; Note Register.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Transferability of Guarantee; Note Register... AND CONDITIONS § 230.06 Transferability of Guarantee; Note Register. A Noteholder may assign, transfer... on the date that the name of the new Noteholder is entered on the Note Register required to...

  14. 22 CFR 221.14 - Transferability of Guarantee; Note Register.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Transferability of Guarantee; Note Register... STANDARD TERMS AND CONDITIONS The Guarantee § 221.14 Transferability of Guarantee; Note Register. A... pledge shall be effective on the date that the name of the new Noteholder is entered on the Note...

  15. 22 CFR 233.06 - Transferability of Guarantee; Note Register.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Transferability of Guarantee; Note Register...-6-STANDARD TERMS AND CONDITIONS § 233.06 Transferability of Guarantee; Note Register. A Noteholder... shall be effective on the date that the name of the new Noteholder is entered on the Note...

  16. 22 CFR 221.14 - Transferability of Guarantee; Note Register.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Transferability of Guarantee; Note Register... STANDARD TERMS AND CONDITIONS The Guarantee § 221.14 Transferability of Guarantee; Note Register. A... pledge shall be effective on the date that the name of the new Noteholder is entered on the Note...

  17. 22 CFR 230.06 - Transferability of Guarantee; Note Register.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Transferability of Guarantee; Note Register... AND CONDITIONS § 230.06 Transferability of Guarantee; Note Register. A Noteholder may assign, transfer... on the date that the name of the new Noteholder is entered on the Note Register required to...

  18. 22 CFR 230.06 - Transferability of Guarantee; Note Register.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Transferability of Guarantee; Note Register... AND CONDITIONS § 230.06 Transferability of Guarantee; Note Register. A Noteholder may assign, transfer... on the date that the name of the new Noteholder is entered on the Note Register required to...

  19. 22 CFR 230.06 - Transferability of Guarantee; Note Register.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Transferability of Guarantee; Note Register... AND CONDITIONS § 230.06 Transferability of Guarantee; Note Register. A Noteholder may assign, transfer... on the date that the name of the new Noteholder is entered on the Note Register required to...

  20. 22 CFR 232.06 - Transferability of Guarantee; Note Register.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Transferability of Guarantee; Note Register... Register. A Noteholder may assign, transfer or pledge an Eligible Note to any Person. Any such assignment... Note Register required to be maintained by the Fiscal Agent pursuant to the Fiscal Agency...