Daily life activity routine discovery in hemiparetic rehabilitation patients using topic models.
Seiter, J; Derungs, A; Schuster-Amft, C; Amft, O; Tröster, G
2015-01-01
Monitoring natural behavior and activity routines of hemiparetic rehabilitation patients across the day can provide valuable progress information for therapists and patients and contribute to an optimized rehabilitation process. In particular, continuous patient monitoring could add type, frequency and duration of daily life activity routines and hence complement standard clinical scores that are assessed for particular tasks only. Machine learning methods have been applied to infer activity routines from sensor data. However, supervised methods require activity annotations to build recognition models and thus require extensive patient supervision. Discovery methods, including topic models could provide patient routine information and deal with variability in activity and movement performance across patients. Topic models have been used to discover characteristic activity routine patterns of healthy individuals using activity primitives recognized from supervised sensor data. Yet, the applicability of topic models for hemiparetic rehabilitation patients and techniques to derive activity primitives without supervision needs to be addressed. We investigate, 1) whether a topic model-based activity routine discovery framework can infer activity routines of rehabilitation patients from wearable motion sensor data. 2) We compare the performance of our topic model-based activity routine discovery using rule-based and clustering-based activity vocabulary. We analyze the activity routine discovery in a dataset recorded with 11 hemiparetic rehabilitation patients during up to ten full recording days per individual in an ambulatory daycare rehabilitation center using wearable motion sensors attached to both wrists and the non-affected thigh. We introduce and compare rule-based and clustering-based activity vocabulary to process statistical and frequency acceleration features to activity words. Activity words were used for activity routine pattern discovery using topic models based on Latent Dirichlet Allocation. Discovered activity routine patterns were then mapped to six categorized activity routines. Using the rule-based approach, activity routines could be discovered with an average accuracy of 76% across all patients. The rule-based approach outperformed clustering by 10% and showed less confusions for predicted activity routines. Topic models are suitable to discover daily life activity routines in hemiparetic rehabilitation patients without trained classifiers and activity annotations. Activity routines show characteristic patterns regarding activity primitives including body and extremity postures and movement. A patient-independent rule set can be derived. Including expert knowledge supports successful activity routine discovery over completely data-driven clustering.
ERIC Educational Resources Information Center
Birch, Sandra K.; Pettus, Alvin M.
Various topics on water and water conservation are discussed, each general topic followed by a student activity. Topics include: (1) importance of water; (2) water in the environment; (3) getting water to and from homes (making water usable; treating wastewater; on-site systems, including water wells and septic tanks); (4) relationship between…
Activities for Preschoolers--A Laboratory Manual for Use by Child-Care Teacher-Aide Students.
ERIC Educational Resources Information Center
Constantine, Jean
This laboratory manual for use by child care and teacher aide students is arranged by topic according to the months and holidays of the school year. Suggested activities, songs, fingerplays, and poems are included for each topic, along with a list of related resource books. Many of the activities and songs include a number in parentheses following…
NREL: International Activities - U.S.-China Renewable Energy Industries
place in Dunhuang, Gansu Province in China on July 20-21, 2017. Discussion topics included renewable Promote Renewable Energy Deployment." View the agenda and topics, speakers, and presentations. Third MOUs between U.S. and Chinese entities were signed. Topics included concentrating solar power
Three Activities To Assist Biology Teachers in Presenting Conceptually Difficult Topics.
ERIC Educational Resources Information Center
Taylor, Neil; Tulip, David
1997-01-01
Outlines three activities for different areas of biology that can serve as motivators for students or as demonstrations. Each activity is easy to organize and uses available materials. Topics include evolution, anaerobic respiration, and heat loss. (DDR)
Group Discussion Topics. Revised Edition.
ERIC Educational Resources Information Center
Area Education Agency 7, Cedar Falls, IA.
A collection of group disussion topics, developed and field-tested by a group of Iowa teachers, is presented in this guide. Twenty-eight topics for K-6 students, 24 topics for K-12 students, and 7 topics for students in grades 7-12 are included. Warm-up activities are given for introducing some of the topics, and lists of questions to provoke…
ERIC Educational Resources Information Center
Sunal, Dennis W.; Tracy, Dyanne M., Eds.
1991-01-01
A learning cycle activity which allows students to practice process skills by sieving different size fractions of sediments is described. Science topics include weathering, erosion, streams, sedimentation, sedimentary rocks, soils, beaches, dunes, or glacial deposits. Mathematics topics include number lines, ordinal numbers, greater than/less…
ERIC Educational Resources Information Center
Alaska State Dept. of Education, Juneau.
Recycling is a very important aspect of conserving the environment for future generations. This guide addresses the topic of litter prevention for the Alaskan environment and contains 42 activities. Activity topics covered include Natural Cycles, Human Interruption of Natural Cycles, Reduce, Reuse, Recycle and Recycled Classroom. Grade level,…
Reinventing the Science Curriculum
ERIC Educational Resources Information Center
Bybee, Rodger W.; Van Scotter, Pamela
2007-01-01
For many, the dominant model of curriculum development in science includes generating a topic, clarifying science content, identifying activities associated with the topic, and figuring out an assessment. Unfortunately, this approach tends to overemphasize activities and underemphasize mastery of science concepts and the process of scientific…
The Chemistry of Fitness. Active Activities.
ERIC Educational Resources Information Center
Bergandine, David R.; And Others
1991-01-01
The outline for a unit on the chemistry of fitness and nutrition is presented. Topics discussed include the organic basis of life, functional groups, kitchen experiments, micronutrients, energetics, fitness vs. fatness, current topics, and evaluation. This unit reviews the basic concepts of chemical bonding, acid-base chemistry, stoichiometry, and…
Life Sciences: Curriculum Resources and Activities for School Librarians and Teachers.
ERIC Educational Resources Information Center
Bain, Amy; Richer, Janet; Weckman, Janet
This book provides resources to teachers and librarians for creating thematic units on specific topics targeting grades K-8. Each topic includes key concepts, comprehensive teaching resources, teaching resources (nonfiction children's literature), reading selections (fiction children's literature), science activities, creative writing and art…
Earth Sciences: Curriculum Resources and Activities for School Librarians and Teachers.
ERIC Educational Resources Information Center
Bain, Amy; Richer, Janet; Weckman, Janet
This book provides resources to teachers and librarians for creating thematic units on specific topics targeting grades K-8. Each topic includes key concepts, comprehensive teaching resources, teaching resources (nonfiction children's literature), reading selections (fiction children's literature), science activities, creative writing and art…
Physical Sciences: Curriculum Resources and Activities for School Librarians and Teachers.
ERIC Educational Resources Information Center
Bain, Amy; Richer, Janet; Weckman, Janet
This book provides resources to teachers and librarians for creating thematic units on specific topics targeting grades K-8. Each topic includes key concepts, comprehensive teaching resources, teaching resources (nonfiction children's literature), reading selections (fiction children's literature), science activities, creative writing and art…
Kids and Chemistry: Large Event Guide.
ERIC Educational Resources Information Center
Tinnesand, Michael
This guide is intended to provide Kids and Chemistry (K&C) with a variety of age-appropriate, fun, and safe demonstrations. It features information on planning a large event and includes safety guidelines. Several activities are included under each major topic. Topics include: (1) Acids and Bases; (2) Unsigned; (3) Kool Tie-Dye; (4) Secret…
Professional Development Training. ACTWU Insurance Department.
ERIC Educational Resources Information Center
Martin, Sabrina Budasi
This curriculum guide provides materials for a 10-week professional development training course. A course outline and list of topics is followed by the plans for the 10 lessons. Components of these lesson plans include topics; objectives; materials needed; lesson outline with activities and discussion; and student handouts. Lesson topics are as…
77 FR 70423 - State Energy Advisory Board (STEAB)
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-26
... STEAB Strategic Planning Subcommittee, and provide an update to the Board on routine business matters and other topics of interest, and follow-up on activities of the Weatherization Taskforce's meeting at... be made to include requested topic(s) on the agenda. The Chair of the Board is empowered to conduct...
ERIC Educational Resources Information Center
Lee, Tom E.; And Others
This compilation of resource units concerns the latest developments in space biology. Some of the topics included are oxygen consumption, temperature, radiation, rhythms, weightlessness, acceleration and vibration stress, toxicity, and sensory and perceptual problems. Many of the topics are interdisciplinary and relate biology, physiology,…
Instructor-Created Activities to Engage Undergraduate Nursing Research Students.
Pierce, Linda L; Reuille, Kristina M
2018-03-01
In flipped or blended classrooms, instruction intentionally shifts to a student-centered model for a problem-based learning approach, where class time explores topics in greater depth, creating meaningful learning opportunities. This article describes instructor-created activities focused on research processes linked to evidence-based practice that engage undergraduate nursing research students. In the classroom, these activities include individual and team work to foster critical thinking and stimulate student discussion of topic material. Six activities for small and large student groups are related to quantitative, qualitative, and both research processes, as well as applying research evidence to practice. Positive student outcomes included quantitative success on assignments and robust student topic discussions, along with instructor-noted overall group engagement and interest. Using these activities can result in class time for the construction of meaning, rather than primarily information transmission. Instructors may adopt these activities to involve and stimulate students' critical thinking about research and evidence-based practice. [J Nurs Educ. 2018;57(3):174-177.]. Copyright 2018, SLACK Incorporated.
Active Learning and Teaching: Improving Postsecondary Library Instruction.
ERIC Educational Resources Information Center
Allen, Eileen E.
1995-01-01
Discusses ways to improve postsecondary library instruction based on theories of active learning. Topics include a historical background of active learning; student achievement and attitudes; cognitive development; risks; active teaching; and instructional techniques, including modified lectures, brainstorming, small group work, cooperative…
Energy Education in Elementary Social Studies. Holt Databank System.
ERIC Educational Resources Information Center
Minnesota State Energy Agency, St. Paul.
This document provides elementary teachers with an annotated index according to grade levels 1-6 of energy education topics in the "Holt Databank System" (Holt, Rinehart and Winston), followed by suggestions for activities related to the topics. Indexed topics, which comprise a major portion of the document, include basic energy information,…
The Ecological Classroom: Environmental Education Activities K-12.
ERIC Educational Resources Information Center
Gillam, David A.; And Others
1995-01-01
Provides interdisciplinary ideas to accompany environmental education activities for kindergarten through grade 12. Topics of the activities include water pollution, soil erosion, and salmon homing instincts. Interdisciplinary areas include fine arts, language arts, and social studies. (DDR)
ERIC Educational Resources Information Center
Blatt, Gloria T.
This paper discusses the thematic unit as a series of activities including reading, discussions, drama sessions, art workshops, games, writing, and movies, all revolving around a single topic. Students are free to seek and select their own books or stories within the topic and to read at their own pace. The thematic unit also includes a heightened…
Technology Systems. Laboratory Activities.
ERIC Educational Resources Information Center
Brame, Ray; And Others
This guide contains 43 modules of laboratory activities for technology education courses. Each module includes an instructor's resource sheet and the student laboratory activity. Instructor's resource sheets include some or all of the following elements: module number, course title, activity topic, estimated time, essential elements, objectives,…
Tearing Plastic: A Laboratory Exercise on Fractals and Hyperbolic Geometry
ERIC Educational Resources Information Center
Taylor, Ron; Timberlake, Todd
2007-01-01
In this article we describe a hands-on activity for a liberal arts mathematics course that focuses on the beauty and unity of mathematics. The purpose of the activity is to tie together several topics in the context of a "real-world" situation. These topics include: fractals, non-Euclidean geometry, symmetry, and Platonic solids. This activity…
Making Algebra Come Alive: Student Activities & Teacher Notes. Math Assessment Series.
ERIC Educational Resources Information Center
Posamentier, Alfred S.
This book contains a set of versatile enrichment exercises that cover a very broad range of mathematical topics and applications in algebra from the Moebius strip to the googol. Several criteria have been used in developing the activities and selecting the topics that are included. All of them bear heavily and equally on concerns for curriculum…
2016-10-01
absence of topical antibiotics, are immediately colonized by gram -positive skin flora, such as Staphylococcus aureus. Gram -negative bacteria such as...complications. Silver sulfadiazine is not active against fungal infections,4 and its side effects include staining of the treated burn wound, allergic
Introductory Industrial Technology I. Laboratory Activities.
ERIC Educational Resources Information Center
Towler, Alan L.; And Others
This guide contains 36 learning modules intended for use by technology teachers and students in grades 7 and 8. Each module includes a student laboratory activity and instructor's resource sheet. Each student activity includes the following: activity topic and overview, challenge statement, objectives, vocabulary/concepts reinforced,…
Introductory Industrial Technology II. Laboratory Activities.
ERIC Educational Resources Information Center
Towler, Alan L.
This guide contains 29 learning modules intended for use by technology teachers and students in grade 8. Each module includes a student laboratory activity and instructor's resource sheet. Each student activity includes the following: activity topic and overview, challenge statement, objectives, vocabulary/concepts reinforced, equipment/supplies,…
Activities in Teaching Weather
ERIC Educational Resources Information Center
Tonn, Martin
1977-01-01
Presented is a unit composed of activities for teaching weather. Topics include cloud types and formation, simple weather instruments, and the weather station. Illustrations include a weather chart and instruments. A bibliography is given. (MA)
7 CFR 3430.704 - Project types and priorities.
Code of Federal Regulations, 2014 CFR
2014-01-01
...) Technical Topic Areas. Biomass Research and Development Initiative (BRDI) awards shall be directed (in... topic areas: (1) Feedstocks Development. Research, development, and demonstration activities regarding feedstocks and feedstock logistics (including the harvest, handling, transport, preprocessing, and storage...
7 CFR 3430.704 - Project types and priorities.
Code of Federal Regulations, 2013 CFR
2013-01-01
...) Technical Topic Areas. Biomass Research and Development Initiative (BRDI) awards shall be directed (in... topic areas: (1) Feedstocks Development. Research, development, and demonstration activities regarding feedstocks and feedstock logistics (including the harvest, handling, transport, preprocessing, and storage...
7 CFR 3430.704 - Project types and priorities.
Code of Federal Regulations, 2012 CFR
2012-01-01
...) Technical Topic Areas. Biomass Research and Development Initiative (BRDI) awards shall be directed (in... topic areas: (1) Feedstocks Development. Research, development, and demonstration activities regarding feedstocks and feedstock logistics (including the harvest, handling, transport, preprocessing, and storage...
Graphing Calculators, the CBL2[TM] and TI-Interactive[TM] in High School Science.
ERIC Educational Resources Information Center
Molnar, Bill
This collection of activities is designed to show how TI-Interactive[TM] and Calculator-based Laboratories (CBL) can be used to explore topics in high school science. The activities address such topics as specific heat, Boyle's Law, Newton's Law of Cooling, and Antarctic Ozone Levels. Teaching notes and calculator instructions are included as are…
Making Pre-Algebra Come Alive: Student Activities & Teacher Notes. Math Assessment Series.
ERIC Educational Resources Information Center
Posamentier, Alfred S.
This book contains a set of versatile enrichment exercises that cover a very broad range of mathematical topics and applications in pre-algebra from the Moebius strip to the googol. Several criteria have been used in developing the activities and selecting the topics that are included. All of them bear heavily and equally on concerns for…
Using Weeds and Wildflowers to Study Plants.
ERIC Educational Resources Information Center
Nowak, Nancy
1984-01-01
Offers suggestions for activities in which local weeds and wildflowers are used to study a variety of topics. These topics include classification, ecological succession, and mapping. Also lists the types of experiments students can perform with these plants. (JN)
NASA Technical Reports Server (NTRS)
Marshall, Jospeh R.; Morris, Allan T.
2007-01-01
Since 2003, AIAA's Computer Systems and Software Systems Technical Committees (TCs) have developed a database that aids technical committee management to map technical topics to their members. This Topics/Interest (T/I) database grew out of a collection of charts and spreadsheets maintained by the TCs. Since its inception, the tool has evolved into a multi-dimensional database whose dimensions include the importance, interest and expertise of TC members and whether or not a member and/or a TC is actively involved with the topic. In 2005, the database was expanded to include the TCs in AIAA s Information Systems Group and then expanded further to include all AIAA TCs. It was field tested at an AIAA Technical Activities Committee (TAC) Workshop in early 2006 through live access by over 80 users. Through the use of the topics database, TC and program committee (PC) members can accomplish relevant tasks such as: to identify topic experts (for Aerospace America articles or external contacts), to determine the interest of its members, to identify overlapping topics between diverse TCs and PCs, to guide new member drives and to reveal emerging topics. This paper will describe the origins, inception, initial development, field test and current version of the tool as well as elucidate the benefits and insights gained by using the database to aid the management of various TC functions. Suggestions will be provided to guide future development of the database for the purpose of providing dynamics and system level benefits to AIAA that currently do not exist in any technical organization.
Activated Sludge. Student Manual. Biological Treatment Process Control.
ERIC Educational Resources Information Center
Boe, Owen K.; Klopping, Paul H.
This student manual contains the textual material for a seven-lesson unit on activated sludge. Topic areas addressed in the lessons include: (1) activated sludge concepts and components (including aeration tanks, aeration systems, clarifiers, and sludge pumping systems); (2) activated sludge variations and modes; (3) biological nature of activated…
Science Activities for Children 3 to 9 Years Old.
ERIC Educational Resources Information Center
Nelson, Bonnie E.
Activities in the life and physical sciences are provided (in separate sections) for preschool and elementary school students. Life science activities include those related to plants, soil, habitats, fossils, animals, life cycles, food chains, nutrition, and other biologically-oriented topics. Physical science activities include those related to…
Geotechnical support and topical studies for nuclear waste geologic repositories
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1989-01-01
The present report lists the technical reviews and comments made during the fiscal year 1988 and summarizes the technical progress of the topical studies. In the area of technical assistance, there were numerous activities detailed in the next section. These included 24 geotechnical support activities, including reviews of 6 Study Plans (SP) and participation in 6 SP Review Workshops, review of one whole document Site Characterization Plan (SCP) and participation in the Assembled Document SCP Review Workshops by 6 LBL reviewers; the hosting of a DOE program review, the rewriting of the project statement of work, 2 trips to technicalmore » and planning meetings; preparation of proposed work statements for two new topics for DOE, and 5 instances of technical assistance to DOE. These activities are described in a Table in the following section entitled Geoscience Technical Support for Nuclear Waste Geologic Repositories.''« less
Seeing the Sky: 100 Projects, Activities, and Explorations in Astronomy.
ERIC Educational Resources Information Center
Schaaf, Fred
1990-01-01
Fourteen astronomy activities are presented including classroom procedures and questions. Topics include different investigations of the moon, planets, stars, sunsets, light pollution, and rainbows and halos. Additional information on measurements used for observations in astronomy, and rainbow characteristics is included. (CW)
High Flight. Aerospace Activities, K-12.
ERIC Educational Resources Information Center
Oklahoma State Dept. of Education, Oklahoma City.
Following discussions of Oklahoma aerospace history and the history of flight, interdisciplinary aerospace activities are presented. Each activity includes title, concept fostered, purpose, list of materials needed, and procedure(s). Topics include planets, the solar system, rockets, airplanes, air travel, space exploration, principles of flight,…
Overcoming Hurdles Implementing Multi-skilling Policies
2015-03-26
skilled workforce? Chapter II will communicate important concepts found in the literature on skill proficiency topics. These topics include skill...training methods that might improve learning and retention during the acquisition phase. 10 The active interlock modeling (AIM) protocol is a dyadic ...retention, as found in 43 Chapter 2. These techniques include dyadic training methods, overlearning, feedback, peer support, and managerial support
Bioethics in the Laboratory: Synthesis and Interactivity.
ERIC Educational Resources Information Center
Murray, Kevin J.
1999-01-01
Describes the implementation of a bioethics laboratory exercise that incorporates a variety of instructional strategies. In the activity, General Biology students consider relevant and interesting topics of bioethical importance and prepare classroom presentations on the different viewpoints normally attendant to ethical topics. Includes an…
Granner, Michelle L; Sharpe, Patricia A; Burroughs, Ericka L; Fields, Regina; Hallenbeck, Joyce
2010-08-01
This study conducted a newspaper content analysis as part of an evaluation of a community-based participatory research project focused on increasing physical activity through policy and environmental changes, which included activities related to media advocacy and media-based community education. Daily papers (May 2003 to December 2005) from both the intervention and comparison counties were reviewed for topics related to physical activity and an active living environment (e.g. safety, policy, urban design, transportation and recreational resources). A total of 2681 articles from 1764 newspapers were analyzed. The intervention county had a greater proportion of articles on the selected topics. Specifically, the intervention county had a greater proportion of articles in topics related to safety, policy and community initiatives, as well as in sidewalks and recreational facilities; both priority areas for the intervention. Prominence of the articles was assessed using a composite index score. Generally, prominence of the topics analyzed was low. Articles in the sidewalks and recreational facilities topic category in the intervention county had higher prominence scores on average than the comparison county. The study demonstrates that media content analysis can be a valuable component in evaluating community-based interventions.
ERIC Educational Resources Information Center
Marzuki, Ariffin Bin; Peng, J. Y.
A profile of Malaysia is sketched in this paper. Emphasis is placed on the nature, scope, and accomplishments of population activities in the country. Topics and sub-topics include: location and description of the country; population (size, growth patterns, age structure, urban/rural distribution, ethnic and religious composition, migration,…
A Selected, Annotated Bibliography for Fitness Educators.
ERIC Educational Resources Information Center
Whitehead, James R.
1992-01-01
This annotated bibliography, designed for practitioners and those involved in improving practice, contains 218 citations on topics related to youth physical fitness. Topics include children's fitness and activity status; contents of, and rationale for, fitness education; program suggestions, methods, and strategies; drug problems; and fitness…
ERIC Educational Resources Information Center
Population Council, New York, NY.
A profile of Jamaica is sketched in this paper. Emphasis is placed on the nature, scope, and accomplishments of population activities in the country. Topics and sub-topics include: location and description of the island; population - size, growth patterns, age structure, rural/urban distribution, ethnic and religious composition, literacy, future…
ERIC Educational Resources Information Center
Population Council, New York, NY.
A profile of Indonesia is sketched in this paper. Emphasis is placed on the nature, scope, and accomplishments of population activities in the country. Topics and sub-topics include: location and description of the country; population - size, growth patterns, age structure, urban/rural distribution, ethnic and religious composition, migration,…
ERIC Educational Resources Information Center
Keeny, S. M.; And Others
A profile of Taiwan is sketched in this paper. Emphasis is placed on the nature, scope, and accomplishments of population activities in the country. Topics and sub-topics include: location and description of the country; population (size, growth patterns, age structure, urban/rural distribution, ethnic and religious composition, migration,…
ERIC Educational Resources Information Center
Texarkana Regional Arts and Humanities Council, Inc., TX.
Each of the seven study guides combined in this packet provides a lesson that includes a reading or descriptive narrative of the topic, along with teaching objectives, questions to consider, and suggested classroom activities. Topics covered are: (1) "Introduction to the Concept of Folklife"; (2) "Southern Gospel Music and…
Early Adolescence: Active Science for Middle Schoolers.
ERIC Educational Resources Information Center
Padilla, Michael; Griffin, Nancy
1980-01-01
Describes activities appropriate for involving middle school students as active participants in the learning process. Topics discussed include archaeology, bulletin boards, dramatizations, physics experiments using the human body, oceanography, and ecology. (CS)
Art & Music Appreciation. A to Z Active Learning Series.
ERIC Educational Resources Information Center
Forte, Imogene; Schurr, Sandra
This workbook includes high-interest activities, lessons, and projects to further students' interest in and understanding of important exploratory and enrichment topics essential to a balanced middle grades program. The workbook includes lessons and activities that encourage students to learn more about the arts. Instructional strategies are…
Teaching Day-by-Day: A Cornucopia of Activities
ERIC Educational Resources Information Center
Teaching Pre K-8, 2005
2005-01-01
This article presents teacher's guide to daily activities for the month of November. The activities help PreK-12 educators to enhance student development. Topics for this month's activities include literacy, language, math, science, and healthy habits.
Population Education. Awareness Activities.
ERIC Educational Resources Information Center
Brouse, Deborah E.
1990-01-01
Described are awareness activities that deal with human population growth, resources, and the environment. Activities include simulations, mathematical exercises, and discussions of the topic. Specific examples of what individuals can do to help are listed. (KR)
ERIC Educational Resources Information Center
Noyce, Ruth, Ed.
Twenty-four biographical sketches of women in scientific professions are included in this COMETS Profiles package. Each biography relates to a science topic dealt with in one of the instructional modules of COMETS Science (Career Oriented Modules to Explore Topics in Science). The purpose of these materials is to demonstrate to early adolescents…
Agriculture & the Environment. Teacher's Guide.
ERIC Educational Resources Information Center
McMurry, Linda Maston
This teacher's guide offers background information that teachers can use to incorporate topics related to agriculture and the environment into the curriculum. Classroom activities to bring these topics alive for students in grades 6-9 are suggested. Chapters include: (1) Pesticides and Integrated Pest Management; (2) Food Safety; (3) Water…
ERIC Educational Resources Information Center
Barber, Betsy; Ball, Rhonda
This project description is designed to show how graphing calculators and calculator-based laboratories (CBLs) can be used to explore topics in physics and health sciences. The activities address such topics as respiration, heart rate, and the circulatory system. Teaching notes and calculator instructions are included as are blackline masters. (MM)
You and Me and Human Sexuality. Teacher's Manual.
ERIC Educational Resources Information Center
Young, Emily Morrill
This teacher's manual is designed for teaching deaf adolescents about human sexuality. Each chapter is organized into topic objectives, large group content presentation strategies, small group activities, materials, and resources. Topics include: (1) relationships; (2) adolescent growth and development; (3) female and male anatomy; (4) conception,…
Science Activities in Energy: Wind Energy.
ERIC Educational Resources Information Center
Oak Ridge Associated Universities, TN.
Included in this science activities energy package are 12 activities related to wind energy for elementary students. Each activity is outlined on a single card and is introduced by a question. Topics include: (1) At what time of day is there enough wind to make electricity where you live?; (2) Where is the windiest spot on your schoolground?; and…
Preservation and Conservation in the School Library.
ERIC Educational Resources Information Center
Sedinger, Theresa
1992-01-01
Discusses the necessity of preservation and conservation activities in school libraries to save materials such as school newspapers, programs of events, censorship records, board activities, yearbooks, and student projects. Topics discussed include brittle, deteriorating paper; monitoring the physical environment, including heat, light, humidity,…
40 years of topical tretinoin use in review.
Baldwin, Hilary E; Nighland, Marge; Kendall, Clare; Mays, David A; Grossman, Rachel; Newburger, Joan
2013-06-01
Topical tretinoin has been approved for use in dermatology for 40 years and is currently approved for the treatment of acne vulgaris and photodamage. During this time, topical tretinoin has accumulated significant efficacy and safety data in the treatment of acne and photodamaged skin and demonstrated clinical potential for treating a range of other dermatologic conditions. The diverse effects may be due to complex underlying mechanisms of action associated with tretinoin, including keratolytic activity, collagenesis, and other mechanisms associated with the activation of nuclear retinoic acid receptors (RARα, RARβ, and RARγ). In this article, we review the history of topical tretinoin use to date and outline emerging research suggesting that topical tretinoin may have potential clinical use for treating a multitude of other dermatological conditions when used either as monotherapy or in combination with other agents. We also describe newer formulations of topical tretinoin that have been designed to reduce irritation potential. In light of the substantial history of safety and efficacy of topical tretinoin in acne and photodamage, we speculate that it holds promise in treating many additional dermatological conditions, which may be explored in future research.
ERIC Educational Resources Information Center
Dawson, Joan Smithey
This booklet is designed to give teachers resource information about the humane treatment of and care for animals. The topics are presented as springboards for discussion and class activity. Topics include the care of dogs, cats, birds, horses, and fish; wildlife and ecological relationships; and careers with animals. Illustrations on some pages…
MINNETESOL Journal, Volumes 1-12.
ERIC Educational Resources Information Center
MINNETESOL Journal, 1994
1994-01-01
The 12 volumes of the professional journal contain articles on a wide variety of topics on classroom techniques, curriculum design, class activities, and research in English-as-a-Second-Language (ESL) teaching at all educational levels. General topics include: communicating with ESL students; current events in the classroom; cultural test bias;…
Energy Education in Elementary Social Studies. Windows On Our World.
ERIC Educational Resources Information Center
Minnesota State Energy Agency, St. Paul.
This document provides elementary teachers with an annotated index according to (Houghton-Mifflin, 1976), followed by suggestions for activities related to the topics. Indexed topics, which comprise a major portion of the document, include basic energy information, society's dependence on energy, problems and advantages of energy alternatives, and…
Sea Changes. Topics in Marine Earth Science.
ERIC Educational Resources Information Center
Awkerman, Gary L.
This publication is designed for use in standard science curricula to develop oceanologic manifestations of certain science topics. Included are teacher guides, student activities, and demonstrations designed to impart ocean science understanding to high school students. The principal theme of Changes in the Sea is presented in this particular…
What is Your Cosmic Connection to the Elements?
NASA Technical Reports Server (NTRS)
Lochner, J.
2003-01-01
This booklet provides information and classroom activities covering topics in astronomy, physics, and chemistry. Chemistry teachers will find information about the cosmic origin of the chemical elements. The astronomy topics include the big bang, life cycles of small and large stars, supernovae, and cosmic rays. Physics teachers will find information on fusion processes, and physical principles important in stellar evolution. While not meant to replace a textbook, the information provided here is meant to give the necessary background for the theme of :our cosmic connection to the elements." The activities can be used to re-enforce the material across a number of disciplines, using a variety of techniques, and to engage and excite students about the topic. Additional activities, and on-line versions of the activities published here, are available at http://imagine.gsfc.nasa.gov/docs/teachers/elements/.
Traditional Persian topical medications for gastrointestinal diseases
Tafti, Laleh Dehghani; Shariatpanahi, Seyyed Mahyar; Damghani, Mahmoud Mahdavi; Javadi, Behjat
2017-01-01
Drug delivery across the skin is used for several millennia to ease gastrointestinal (GI) ailments in Traditional Persian Medicine (TPM). TPM topical remedies are generally being applied on the stomach, lower abdomen, lower back and liver to alleviate GI illnesses such as dyspepsia, gastritis, GI ulcers, inflammatory bowel disease, intestinal worms and infections. The aim of the present study is to survey the topical GI remedies and plant species used as ingredients for these remedies in TPM. In addition, pharmacological activities of the mentioned plants have been discussed. For this, we searched major TPM textbooks to find plants used to cure GI problems in topical use. Additionally, scientific databases were searched to obtain pharmacological data supporting the use of TPM plants in GI diseases. Rosa × damascena, Pistacia lentiscus, Malus domestica, Olea europaea and Artemisia absinthium are among the most frequently mentioned ingredients of TPM remedies. β-asarone, amygdalin, boswellic acids, guggulsterone, crocin, crocetin, isomasticadienolic acid, and cyclotides are the most important phytochemicals present in TPM plants with GI-protective activities. Pharmacological studies demonstrated GI activities for TPM plants supporting their extensive traditional use. These plants play pivotal role in alleviating GI disorders through exhibiting numerous activities including antispasmodic, anti-ulcer, anti-secretory, anti-colitis, anti-diarrheal, antibacterial and anthelmintic properties. Several mechanisms underlie these activities including the alleviation of oxidative stress, exhibiting cytoprotective activity, down-regulation of the inflammatory cytokines, suppression of the cellular signaling pathways of inflammatory responses, improving re-epithelialization and angiogenesis, down-regulation of anti-angiogenic factors, blocking activity of acetylcholine, etc. PMID:28392893
ERIC Educational Resources Information Center
McDonald's Corp., Oak Brook, IL.
One of five McDonald's Action Packs, this learning package introduces intermediate grade students to basic economic concepts. The fourteen activities include the topics of consumption (4 activities), production (5), the market system (3), a pretest, and a posttest. Specific titles under consumption include The Wonderful Treasure Tree (introduction…
Topical Microbicides and HIV Prevention in the Female Genital Tract
Cottrell, Mackenzie L; Kashuba, Angela D. M.
2014-01-01
Worldwide, HIV disproportionately affects women who are often unable to negotiate traditional HIV preventive strategies such as condoms. In the absence of an effective vaccine or cure, chemoprophylaxis may be a valuable self-initiated alternative. Topical microbicides have been investigated as one such option. The first generation topical microbicides were non-specific, broad-spectrum antimicrobial agents, including surfactants, polyanions, and acid buffering gels, that generally exhibited contraceptive properties. After extensive clinical study, none prevented HIV infection, and their development was abandoned. Second generation topical microbicides include agents with selective mechanisms of antiviral activity. Most are currently being used for, or have previously been explored as, drugs for treatment of HIV. The most advanced of these is tenofovir 1% gel: the first topical agent shown to significantly reduce HIV infection by 39% compared to placebo. This review summarizes the evolution of topical microbicides for HIV chemoprophylaxis, highlights important concepts learned, and offers current and future considerations for this area of research. PMID:24664786
DOE Office of Scientific and Technical Information (OSTI.GOV)
Molnar, Denes
2015-09-01
This report summarizes research activities at Purdue University done as part of the DOE JET Topical Collaboration. These mainly involve calculation of covariant radiative energy loss in the (Djordjevic-)Gyulassy-Levai-Vitev ((D)GLV) framework for relativistic A+A reactions at RHIC and LHC energies using realistic bulk medium evolution with both transverse and longitudinal expansion. The single PDF file provided also includes a report from the entire JET Collaboration.
NASA Astrophysics Data System (ADS)
Hasegawa, Makoto; Tokumitsu, Seika
2016-09-01
The out-of-curriculum project team "Rika-Kobo", organized by undergraduate students, has been actively engaged in a variety of continuous outreach activities in the fields of science and technology including optics and photonics. The targets of their activities cover wide ranges of generations from kids to parents and elderly people, with aiming to promote their interests in various fields of science and technologies. This is an out-of-curriculum project team with about 30 to 40 undergraduate students in several grades and majors. The total number of their activities per year tends to reach 80 to 90 in recent years. Typical activities to be performed by the project team include science classes in elementary and/or secondary schools, science classes at other educational facilities such as science museums, and experiment demonstrations at science events. Popular topics cover wide ranges from explanations and demonstrations of nature phenomena, such as rainbow colors, blue sky, sunset color, to demonstration experiments related to engineering applications, such as polarization of light, LEDs, and optical communications. Experimental topics in optics and photonics are especially popular to the audiences. Those activities are very effective to enhance interests of the audiences in learning related knowledges, irrespective of their generations. Those activities are also helpful for the student members to achieve and/or renew scientific knowledges. In addition, each of the activities provides the student members with effective and advantageous Project-Based-Learning (PBL) style experiences including manufacturing experiences, which are advantageous to cultivate their engineering skills.
Private Cultural Promotion in the Federal Republic of Germany.
ERIC Educational Resources Information Center
Fohrbeck, Karla; Wiesand, Andreas Johannes
Private cultural promotion has become a major topic of interest in cultural policy in recent years. Ranging from personal patronage, to salons, to lifestyle promotion, this document is concerned with presenting the great variety of possible fields of activity in private cultural promotion. Divided into eight chapters the topics covered include:…
Modismos al Momento. (Idioms of Today).
ERIC Educational Resources Information Center
Garfinkel, Alan; And Others
This workbook is designed for second level students of Spanish and contains thirty units, each unit focusing on a selected topic and the Spanish idioms relevant to that topic. Each unit includes a list of the idioms, a dialogue containing the idioms, completion exercises, paraphrase exercises, and suggestions of activities to help students learn…
Marshall Space Flight Center ECLSS technology activities
NASA Technical Reports Server (NTRS)
Wieland, Paul
1990-01-01
Viewgraphs on Environmental Control and Life Support System (ECLSS) technology activities are presented. Topics covered include: analytical development; ECLSS modeling approach; example of water reclamation modeling needs; and hardware development and testing.
ERIC Educational Resources Information Center
Chemecology, 1995
1995-01-01
Includes articles and classroom activities about chemicals in the body entitled: "Your Body's Chemical Factory,""Testing for Catalase Activity,""How Sweet It IS...,""Milking Calcium for All It's Worth," and "Testing for Starch in Plant Products." (MKR)
NASA Astrophysics Data System (ADS)
Baldock, C.
2017-05-01
John Gore’s seminal 1984 paper on gel dosimetry spawned a vibrant research field ranging from fundamental science through to clinical applications. A preliminary bibliometric study was undertaken of the gel dosimetry family of publications inspired by, and resulting from, Gore’s original 1984 paper to determine active growth areas, research trends and hot topics from Gore’s paper up to and including 2016. Themes and trends of the gel dosimetry research field were bibliometrically explored by way of co-occurrence term maps using the titles and abstracts text corpora from the Web of Science database for all relevant papers from 1984 to 2016. Visualisation of similarities was used by way of the VOSviewer visualisation tool to generate cluster maps of gel dosimetry knowledge domains and the associated citation impact of topics within the domains. Heat maps were then generated to assist in the understanding of active growth areas, research trends, and emerging and hot topics in gel dosimetry.
ERIC Educational Resources Information Center
Murphy, Elaine M.; Long, Alison T.
This course outline suggests materials and learning activities on the interrelated causes and consequences of population growth and other population matters. The document describes 15 class sessions which integrate information for sociology, anthropology, psychology, biology, animal behavior, and education. Topics include the history of human…
Six degree of freedom active vibration damping for space application
NASA Technical Reports Server (NTRS)
Haynes, Leonard S.
1993-01-01
Work performed during the period 1 Jan. - 31 Mar. 1993 on six degree of freedom active vibration damping for space application is presented. A performance and cost report is included. Topics covered include: actuator testing; mechanical amplifier design; and neural network control system development and experimental evaluation.
Livable Winter Cities--Leisure Attitudes and Activities.
ERIC Educational Resources Information Center
Neal, Larry; Coles, Roger, Ed.
1989-01-01
The nine articles included in this feature emphasize how leisure, recreation, health and physical activities make winter cities more livable. Specific topics include techniques for teaching about cold weather safety and cold related injuries, Arctic Winter Games, and results of a study on winter recreation in large North American communities. (IAH)
A Child Centered Approach to Dinosaurs.
ERIC Educational Resources Information Center
Strader, William H.; Rinker, Catherine A.
1989-01-01
Describes a curriculum for teaching young children about dinosaurs. Activity topics included Diplodocus eggs, sorting dinosaurs, creating terrariums, and extinction. Describes the incorporation of dinosaur activities into other subject areas and resource materials. (RJC)
Looking at Earth from Space: Teacher's Guide with Activities for Earth and Space Science
NASA Technical Reports Server (NTRS)
Steele, Colleen (Editor); Steele, Colleen; Ryan, William F.
1995-01-01
The Maryland Pilot Earth Science and Technology Education Network (MAPS-NET) project was sponsored by the National Aeronautics and Space Administration (NASA) to enrich teacher preparation and classroom learning in the area of Earth system science. This publication includes a teacher's guide that replicates material taught during a graduate-level course of the project and activities developed by the teachers. The publication was developed to provide teachers with a comprehensive approach to using satellite imagery to enhance science education. The teacher's guide is divided into topical chapters and enables teachers to expand their knowledge of the atmosphere, common weather patterns, and remote sensing. Topics include: weather systems and satellite imagery including mid-latitude weather systems; wave motion and the general circulation; cyclonic disturbances and baroclinic instability; clouds; additional common weather patterns; satellite images and the internet; environmental satellites; orbits; and ground station set-up. Activities are listed by suggested grade level and include the following topics: using weather symbols; forecasting the weather; cloud families and identification; classification of cloud types through infrared Automatic Picture Transmission (APT) imagery; comparison of visible and infrared imagery; cold fronts; to ski or not to ski (imagery as a decision making tool), infrared and visible satellite images; thunderstorms; looping satellite images; hurricanes; intertropical convergence zone; and using weather satellite images to enhance a study of the Chesapeake Bay. A list of resources is also included.
So What's It to Me? Sexual Assault Information for Guys: Activity Guide.
ERIC Educational Resources Information Center
Stringer, Gayle M.; Rants-Rodriguez, Deanna
This document is a group leader activity guide to accompany a sexual assault prevention program focusing on information for male teenagers. Background information, large group activities, comments for small group leaders, extension activities, activity sheets, and transparency masters are included for 15 group activities. These topics are covered…
Search engines, news wires and digital epidemiology: Presumptions and facts.
Kaveh-Yazdy, Fatemeh; Zareh-Bidoki, Ali-Mohammad
2018-07-01
Digital epidemiology tries to identify diseases dynamics and spread behaviors using digital traces collected via search engines logs and social media posts. However, the impacts of news on information-seeking behaviors have been remained unknown. Data employed in this research provided from two sources, (1) Parsijoo search engine query logs of 48 months, and (2) a set of documents of 28 months of Parsijoo's news service. Two classes of topics, i.e. macro-topics and micro-topics were selected to be tracked in query logs and news. Keywords of the macro-topics were automatically generated using web provided resources and exceeded 10k. Keyword set of micro-topics were limited to a numerable list including terms related to diseases and health-related activities. The tests are established in the form of three studies. Study A includes temporal analyses of 7 macro-topics in query logs. Study B considers analyzing seasonality of searching patterns of 9 micro-topics, and Study C assesses the impact of news media coverage on users' health-related information-seeking behaviors. Study A showed that the hourly distribution of various macro-topics followed the changes in social activity level. Conversely, the interestingness of macro-topics did not follow the regulation of topic distributions. Among macro-topics, "Pharmacotherapy" has highest interestingness level and wider time-window of popularity. In Study B, seasonality of a limited number of diseases and health-related activities were analyzed. Trends of infectious diseases, such as flu, mumps and chicken pox were seasonal. Due to seasonality of most of diseases covered in national vaccination plans, the trend belonging to "Immunization and Vaccination" was seasonal, as well. Cancer awareness events caused peaks in search trends of "Cancer" and "Screening" micro-topics in specific days of each year that mimic repeated patterns which may mistakenly be identified as seasonality. In study C, we assessed the co-integration and correlation between news and query trends. Our results demonstrated that micro-topics sparsely covered in news media had lowest level of impressiveness and, subsequently, the lowest impact on users' intents. Our results can reveal public reaction to social events, diseases and prevention procedures. Furthermore, we found that news trends are co-integrated with search queries and are able to reveal health-related events; however, they cannot be used interchangeably. It is recommended that the user-generated contents and news documents are analyzed mutually and interactively. Copyright © 2018 Elsevier B.V. All rights reserved.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-22
... the monograph (75 FR 9767, March 4, 2010) (final rule). The guidance describes the requirements of the... products marketed under the monograph (i.e., products that contain any of the active ingredients permitted under the OTC topical acne drug monograph, including benzoyl peroxide, resorcinol, resorcinol...
ERIC Educational Resources Information Center
Purcell, Edna Jean, Ed.
This is a report of the centennial conference of the University of Wisconsin-Oshkosh. Included are details of centennial activities, topics of discussions, the highlights of a speech by Karl Massanari on performance-based teacher education, and highlights of discussions, even down to transcripts of group discussions. Topics and problems covered in…
ERIC Educational Resources Information Center
Brody, David L.; Cohen, Hindy
2012-01-01
Early childhood educators are increasingly being called upon to deal with emotionally charged topics, which include natural and manmade disasters, war, terror, death, and other traumatic events. At our teachers college, we prepare students to deal with a challenging issue, memory of the Holocaust, through a series of activities and workshops…
International High/Scope Registry Conference Proceedings (Ypsilanti, Michigan, May 8-11, 1996).
ERIC Educational Resources Information Center
High/Scope Educational Research Foundation, Ypsilanti, MI.
These conference proceedings provide summaries of 66 presentations on various aspects of the High/Scope active learning approach for high-risk students, as well as related topics. Topics addressed include: (1) real-life problem solving; (2) songs in daily routines; (3) open-ended art materials; (4) transition strategies; (5) recall ideas for…
NASA/NREN: Next Generation Internet (NGI) Activities
NASA Technical Reports Server (NTRS)
desJardins, Richard; Freeman, Ken
1998-01-01
Various issues associated with next generation internet (NGI) and the NREN (NASA Research and Education Network) activities are presented in viewgraph form. Specific topics include: 1) NREN architecture; 2) NREN applications; and 3) NREN applied research.
Enrichment Activities for Geometry.
ERIC Educational Resources Information Center
Usiskin, Zalman
1983-01-01
Enrichment activities that teach about geometry as they instruct in geometry are given for some significant topics. The facets of geometry included are tessellations, round robin tournaments, geometric theorems on triangles, and connections between geometry and complex numbers. (MNS)
From Greeks to Today: Cipher Trees and Computer Cryptography.
ERIC Educational Resources Information Center
Grady, M. Tim; Brumbaugh, Doug
1988-01-01
Explores the use of computers for teaching mathematical models of transposition ciphers. Illustrates the ideas, includes activities and extensions, provides a mathematical model and includes computer programs to implement these topics. (MVL)
ERIC Educational Resources Information Center
School Science Review, 1984
1984-01-01
Presents 28 activities, games, demonstrations, experiments, and computer programs for biology, chemistry, physics, and conservation education. Background information, laboratory procedures, equipment lists, and instructional strategies are included. Topics include nature conservation, chickens in school, human anatomy, nitrogen cycle, mechanism…
ERIC Educational Resources Information Center
Markle, Sandra
1983-01-01
This science column includes background information, discussion questions, science activities, writing activities, and a bibliography on a different topic each month. The titles of the five installments included in this compilation are: (1) "Chameleons and Other Quick-Change Artists"; (2) "Niagara Falls and Other Super…
Astronomical! 44 Activities, Experiments, and Projects. Classroom Resource 0-27440.
ERIC Educational Resources Information Center
Walker, Ormiston H.
This is a resource book for four major areas of study: basic astronomy, a star's life, the planets, and the atmosphere. The activities and demonstrations included can be done in a classroom setting during the day by using readily available materials. Topics covered include: refracting and reflecting telescopes, star finder, circumpolar…
ERIC Educational Resources Information Center
Shevick, Ed
This book contains hands-on science laboratory activities for grades 4 through 9 that use discrepant events to challenge students. All of the "puzzlers" are based upon science principles and include directions for building gadgets that explain the "puzzlers." Topics covered include: volume conservation, magnetic phenomena,…
ERIC Educational Resources Information Center
Gridley, C. Robert R.
This teaching guide contains 200 activities that are suitable for openers and demonstrations in biology classes. Details are provided regarding the use of these activities. Some of the broad topics under which the activities are organized include algae, amphibians, bacteria, biologists, crustaceans, dinosaurs, ecology, evolution, flowering plants,…
Overview af MSFC's Applied Fluid Dynamics Analysis Group Activities
NASA Technical Reports Server (NTRS)
Garcia, Roberto; Griffin, Lisa; Williams, Robert
2004-01-01
This paper presents viewgraphs on NASA Marshall Space Flight Center's Applied Fluid Dynamics Analysis Group Activities. The topics include: 1) Status of programs at MSFC; 2) Fluid Mechanics at MSFC; 3) Relevant Fluid Dynamics Activities at MSFC; and 4) Shuttle Return to Flight.
ERIC Educational Resources Information Center
Wagner, Richard
1990-01-01
Presented are activities suggested through Project L.A.B.S. that involve the topic of toxicology. Activities include suggested research, the risk benefit seesaw, human-made compounds, legislation, a historical perspective, and health. A suggested readings list is provided. (KR)
INITIATIVES AND TREATMENT OF MERCURY IN ABANDONED MINES
This presentation discusses EPA's research activities and mitigation activities for mercury contaminated mine sites at the International meeting on mercury and artisanal gold mining in Lima, Peru. The topics discussed included the toxicological and enviornmental tasks associated ...
ERIC Educational Resources Information Center
School Science Review, 1986
1986-01-01
Describes 26 different activities, experiments, demonstrations, and computer simulations in various topics in science. Includes instructional activities dealing with mural ecology, surface area/volume ratios, energy transfer in ecosystems, electrochemical simulations, alternating and direct current, terminal velocity, measuring the size of the…
Coordinating Council. Second Meeting: International Acquisitions
NASA Technical Reports Server (NTRS)
1990-01-01
The theme of this NASA Scientific and Technical Information Program Coordinating Council was International Acquisitions. Included are both visuals for presentations and reports on discussions related to the topics. Presentations were made on the following topics: Coordination council organization international plan, STI global network, International aerospace climate, Foreign exchange program, Foreign activities RMS & AIAA, NASA translation program, A.F. machine translation system, and CIRC cooperation.
ERIC Educational Resources Information Center
New York State Education Dept., Albany. Curriculum Development Center.
This is a curriculum guide for teaching dental health for grades 4-6. Each topic area is outlined under the headings of: (1) reference; (2) major understandings and fundamental concepts; (3) suggested teaching aids and learning activities; and (4) supplementary information for teachers. Main topics include: (1) growth and development of teeth; (2)…
Gorman, Gregory; Sokom, Simara; Coward, Lori; Arnold, John J
2017-01-01
Topical gels compounded by pharmacists are important clinical tools for the management of pain. Nevertheless, there is often a dearth of information about the chemical stability of drugs included in these topical formulations, complicating the assignment of beyond-use dating. The purpose of this study was to develop a high-performance liquid chromatography photodiode array-based stability-indicating assay that could simultaneously resolve six drugs (amitriptyline, baclofen, clonidine, gabapentin, ketoprofen, lidocaine) commonly included in topical gels for pain management and their potential degradation products. Furthermore, this method was applied to the determination of beyond-use dating of combinations of these drugs prepared in commonly utilized bases (Lipobase, Lipoderm, Pluronic organogel). Gabapentin was determined to be the least stable component in all formulations tested. Measured stability ranged between 7 to 49 days depending on the base and other active drugs present in the formulation. In the absence of gabapentin, baclofen was the next least stable component, lasting for 120 days, regardless of the type of formulating base used. Copyright© by International Journal of Pharmaceutical Compounding, Inc.
Active-Twist Rotor Control Applications for UAVs
NASA Technical Reports Server (NTRS)
Wilbur, Matthew L.; Wilkie, W. Keats
2004-01-01
The current state-of-the-art in active-twist rotor control is discussed using representative examples from analytical and experimental studies, and the application to rotary-wing UAVs is considered. Topics include vibration and noise reduction, rotor performance improvement, active blade tracking, stability augmentation, and rotor blade de-icing. A review of the current status of piezoelectric fiber composite actuator technology, the class of piezoelectric actuators implemented in active-twist rotor systems, is included.
NREL: International Activities - Working with Us
opportunities to develop technology partnerships and researcher-driven collaboration. Technology Partnerships expertise, including our energy analysis capabilities. Researcher-Driven Collaboration NREL scientists formal means, such as collaboration on specific technical topics. NREL researchers also actively
NASA Technical Reports Server (NTRS)
Powers. W. Edward
2010-01-01
This viewgraph presentation reviews the medical screening process and spacecraft launch and landing mission activities for astronauts. The topics include: 1) Launch and Landing Mission Overview; 2) Available Resources; and 3) Medical Screening Process.
NASA Astrophysics Data System (ADS)
Demange, Gabrielle; Wooders, Myrna
2005-01-01
Broad and diverse ranges of activities are conducted within and by organized groups of individuals, including political, economic and social activities. These activities have recently become a subject of intense interest in economics and game theory. Some of the topics investigated in this collection are models of networks of power and privilege, trade networks, co-authorship networks, buyer-seller networks with differentiated products, and networks of medical innovation and the adaptation of new information. Other topics are social norms on punctuality, clubs and the provision of club goods and public goods, research and development and collusive alliances among corporations, and international alliances and trading agreements. While relatively recent, the literature on game theoretic studies of group formation in economics is already vast. This volume provides an introduction to this important literature on game-theoretic treatments of situations with networks, clubs, and coalitions, including some applications.
Discovering Geography: Teacher Created Activities for High School and Middle School.
ERIC Educational Resources Information Center
Petersen, James F., Ed.
This guide contains 20 classroom activities designed by teachers to study topics in geography with the eventual goal of aiding in the development of geographic literacy in students. The various activities involve map reading skills, climatology, current events, urban development, and community planning. Each activity presentation includes an event…
Reduction of serum TARC levels in atopic dermatitis by topical anti-inflammatory treatments.
Yasukochi, Yumi; Nakahara, Takeshi; Abe, Takeru; Kido-Nakahara, Makiko; Kohda, Futoshi; Takeuchi, Satoshi; Hagihara, Akihito; Furue, Masutaka
2014-09-01
Serum thymus and activation-regulated chemokine (TARC) levels are associated with the disease activity of patients with atopic dermatitis (AD) and sensitively reflect short-term changes in skin conditions. The main treatment for AD is topical agent application. This study investigated the relationship between serum TARC levels and the dosage of topical agents, including corticosteroids and/or tacrolimus, in patients with AD. The serum TARC levels of 56 AD patients and the amounts of topical agents prescribed to them were investigated retrospectively. The weekly reduction in serum TARC levels and weekly dosage of topical agents among AD patients were compared and their associations were evaluated. The dosage of topical agents was closely related to serum TARC levels. One gram of strong rank steroid or the equivalent amount of steroid/tacrolimus is required to reduce serum TARC levels by 9.94 pg/mL weekly in moderate to severe AD patients. Higher initial TARC levels require more topical agent, which results in a more rapid decrease in TARC levels. The serum TARC levels and eosinophil numbers in peripheral blood are significantly correlated. Serum TARC level improvement and topical agent dosage are strongly correlated. TARC and eosinophil numbers are significantly correlated, but the wider range of TARC levels seems to be clinically more useful for monitoring AD severity. The serum TARC level is a very sensitive biomarker for monitoring the severity and treatment response in AD.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nuhn, Heinz-Dieter
2003-03-19
This is the summary of the activities in working group C, ''Application to FELs,'' which was based in the Bithia room at the Joint ICFA Advanced Accelerator and Beam Dynamics Workshop on July 1-6, 2002 in Chia Laguna, Sardinia, Italy. Working group C was small in relation to the other working groups at that workshop. Attendees include Enrica Chiadroni, University of Rome ape with an identical pulse length. ''La Sapienza'', Luca Giannessi, ENEA, Steve Lidia, LBNL, Vladimir Litvinenko, Duke University, Patrick Muggli, UCLA, Alex Murokh, UCLA, Heinz-Dieter Nuhn, SLAC, Sven Reiche, UCLA, Jamie Rosenzweig, UCLA, Claudio Pellegrini, UCLA, Susan Smith,more » Daresbury Laboratory, Matthew Thompson, UCLA, Alexander Varfolomeev, Russian Research Center, plus a small number of occasional visitors. The working group addressed a total of nine topics. Each topic was introduced by a presentation, which initiated a discussion of the topic during and after the presentation. The speaker of the introductory presentation facilitated the discussion. There were six topics that were treated in stand-alone sessions of working group C. In addition, there were two joint sessions, one with working group B, which included one topic, and one with working group C, which included two topics. The presentations that were given in the joint sessions are summarized in the working group summary reports for groups B and D, respectively. This summary will only discuss the topics that were addressed in the stand-alone sessions, including Start-To-End Simulations, SASE Experiment, PERSEO, ''Optics Free'' FEL Oscillators, and VISA II.« less
BMY 30047: A novel topically active retinoid with low local and systemic toxicity
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nair, X.; Quigley, J.; Tramposch, K.M.
In the treatment of various dermatological disorders, topically applied retinoids have potential therapeutic use with the advantage of improved localized activity and lower toxicity over systemically administered retinoids. However, most retinoids cause a significant degree of local irritation. In the present study, the ability to produce local activity with low local irritation potential was evaluated with a novel retinoic acid derivative. BMY 30047 (11-cis, 13-cis-12-hydroxymethylretinoic acid delta-lactone) is one of a series of retinoic acid derivatives in which the carboxyl function of the polar end was modified with the aim of achieving reduced local irritation and systemic toxicity while retainingmore » the local therapeutic effect. BMY 30047 was evaluated and compared with all-trans retinoic acid for topical retinoid activity in several preclinical assay systems, including the utricle reduction assay in rhino mice, 12-o-tetradecanoylphorbol 13-acetate ester-stimulated ornithine decarboxylase induction in hairless mice and the UV light-induced photodamaged skin model in hairless mice. BMY 30047 was assessed for retinoid-type side effects by evaluating the skin irritation potential in rabbits after repeated topical application, and hypervitaminosis A-inducing potential in mice after i.p. injection. BMY 30047 demonstrated significant topical retinoid activity in several in vivo models with less skin irritation potential relative to the most used clinical concentrations of all-trans retinoic acid. BMY 30047 also showed very little systemic activity and did not produce any evidence of hypervitaminosis A syndrome at systemic doses 20 times greater than the no-effect dose of all-trans retinoic acid.« less
ERIC Educational Resources Information Center
School Science Review, 1989
1989-01-01
Twenty-two activities are presented. Topics include: acid rain, microcomputers, fish farming, school-industry research projects, enzymes, equilibrium, assessment, science equipment, logic, Archimedes principle, electronics, optics, and statistics. (CW)
Astronomy Activities for the Classroom.
ERIC Educational Resources Information Center
Cain, Peggy W.; Welch, Daniel W.
Presented are middle school level, activity-oriented astronomy activities developed as a result of an earth science workshop for teachers. Topics include: (1) sun and moon position and measurement; (2) daily, yearly, and seasonal changes in the sun's position; (3) shapes and positions of planetary orbits; (4) eclipses; (5) properties of light; (6)…
Bits & Bytes of Dental Health. Teaching Dental Health in the Classroom.
ERIC Educational Resources Information Center
Daugs, Donald R.; Cazier, Calvert F.
Instructional activities in this manual are designed for integration into the existing curriculum framework for health education. The activities are organized in sections corresponding to major topics. Each section begins with background information intended to provide content background for the teacher. Each activity includes a curriculum…
Recent meteor observing activities in Japan
NASA Astrophysics Data System (ADS)
Yamamoto, M.
2005-02-01
The meteor train observation (METRO) campaign is described as an example of recent meteor observing activity in Japan. Other topics of meteor observing activities in Japan, including Ham-band radio meteor observation, the ``Japan Fireball Network'', the automatic video-capture software ``UFOCapture'', and the Astro-classroom programme are also briefly introduced.
Successful Strategies for Rapidly Upgrading PTC Windchill 9.1 to Windchill 10.1 on a Light Budget
NASA Technical Reports Server (NTRS)
Shearrow, Charles A.
2013-01-01
Topics covered include: The Frugal Times Historical Upgrade Process; Planning for Possible Constraints; PTC Compatibility Matrix; In-Place Upgrade Process; Pre-Upgrade Activities; Upgrade Activities; Post Upgrade Activities; Results of the Upgrade; Tips for an Upgrade On a Shoestring Budget.
Ladybugs and Lettuce Leaves. Teachers' Manual.
ERIC Educational Resources Information Center
Barnes, Tracy; And Others
This is a guide for use with "Ladybugs and Lettuce Leaves" activity cards which are activities for elementary school students (grades 4 to 6) focusing on gardening. It includes educational objectives for each topic as well as lists of vocabulary words, comments, questions for discussion, additional activities, and resources. An interdisciplinary…
The Enlightenment Revisited: Sources & Interpretations. Learning Activities.
ERIC Educational Resources Information Center
Donato, Clorinda; And Others
This resource book provides 26 learning activities with background materials for teaching about the Enlightenment. Topics include: (1) "What Was the Enlightenment?"; (2) "An Introduction to the Philosophes"; (3) "Was the Enlightenment a Revolt Against Rationalism?"; (4) "Were the Philosophes Democrats? A…
University Faculty Teaching Activities in an Electronic Curriculum.
ERIC Educational Resources Information Center
Eisner, John; Carter, Thomas
1989-01-01
Discusses the changes in the instructional activities of university faculty members as a result of new computer-related educational technologies. Topics discussed include computer-assisted instruction; computer-managed instruction; optical discs; microcomputers; lecturing versus computer-based tutorials; videodiscs; computerized evaluative…
Selected Topics in Overset Technology Development and Applications At NASA Ames Research Center
NASA Technical Reports Server (NTRS)
Chan, William M.; Kwak, Dochan (Technical Monitor)
2002-01-01
This paper presents a general overview of overset technology development and applications at NASA Ames Research Center. The topics include: 1) Overview of overset activities at NASA Ames; 2) Recent developments in Chimera Grid Tools; 3) A general framework for multiple component dynamics; 4) A general script module for automating liquid rocket sub-systems simulations; and 5) Critical future work.
Proceedings of the 4th Annual Workshop: Advances in Smart Materials for Aerospace Applications
NASA Technical Reports Server (NTRS)
Hardy, Robin C. (Editor); Simpson, Joycelyn O. (Editor)
1996-01-01
The objective of the Fourth Annual Conference on Advances in Smart Materials for Aerospace Applications was to provide a forum for technical dialogue on numerous topics in the area of smart materials. The proceedings presented herein represent the technical contributions of the participants of the workshop. Topics addressed include shape memory alloys, ferroelectrics, fiber optics, finite element simulation, and active control.
ERIC Educational Resources Information Center
Vavougios, Dionisios; Verevi, Alkistis; Papalexopoulos, Panagiotis F.; Verevi, Crystallia-Ioanna; Panagopoulou, Athanasia
2016-01-01
This article reviews 24 years of research focused on science education for students with learning and other disabilities. Our results are based on 53 articles from 2 relevant databases. We hereby present and discuss the results of the most popular topics investigated, which include: constructivism, exploratory learning, hands-on activities,…
Making the Math/Science Connection.
ERIC Educational Resources Information Center
Sherman, Laurel Galbraith
1989-01-01
Suggestions are made for activities that combine the teaching of math and science. Math concepts include: graphing, estimating, measurement, statistics, geometry, and logic. Science topics include: plant reproduction, solar system, forces, longitude and latitude, Earth's magnetic field, nutrition, and heat. (IAH)
Demonstration of Zoospore Activities by Fungi.
ERIC Educational Resources Information Center
McCarter, States M.
1978-01-01
The demonstrations and experiments described in this article are appropriate for junior high school and older students, including beginning students in college biology or botany. Included are culture and observation of zoospores, zoospore attraction to plant roots, and other topics. (BB)
ERIC Educational Resources Information Center
Harper, Barry; Hedberg, John G.; Wright, Rob
2000-01-01
Discusses the use of constructivist frameworks to develop effective and successful learning environments, including educational software. Topics include technology supporting reform; virtuality and multimedia; attributes of interactive multimedia and virtual reality; and examples of context and learner active participation. (Contains 35…
NASA Technical Reports Server (NTRS)
Chambers, Joseph R.
2005-01-01
The goal of this publication is to provide an overview of the topic of revolutionary research in aeronautics at Langley, including many examples of research efforts that offer significant potential benefits, but have not yet been applied. The discussion also includes an overview of how innovation and creativity is stimulated within the Center, and a perspective on the future of innovation. The documentation of this topic, especially the scope and experiences of the example research activities covered, is intended to provide background information for future researchers.
Carter, Sarah P; Osborne, Laura J; Renshaw, Keith D; Allen, Elizabeth S; Loew, Benjamin A; Markman, Howard J; Stanley, Scott M
2018-02-01
Long-distance communication has been frequently identified as essential to military couples trying to maintain their relationship during a deployment. Little quantitative research, however, has assessed the types of topics discussed during such communication and how those topics relate to overall relationship satisfaction. The current study draws on a sample of 56 Army couples who provided data through online surveys while the service member was actively deployed. These couples provided information on current marital satisfaction, topics discussed during deployment (problem talk, friendship talk, love talk), and how they communicated via synchronous media (e.g., phone calls, video calls) and letters during deployment. Nonparametric Friedman tests followed by paired t tests revealed that synchronous communication was primarily utilized for friendship talk, whereas letters included friendship talk and love talk in similar amounts. Both synchronous communication and letters included less problem talk than other topics. In mixed-level modeling, only topics of communication for synchronous media (not for letters) were related to relationship satisfaction. Love talk via synchronous media was related to higher relationship satisfaction, whereas problem talk via synchronous media was related to less relationship satisfaction. The current study offers the first quantitative assessment of topics within deployment communication media and associations with relationship satisfaction. (PsycINFO Database Record (c) 2018 APA, all rights reserved).
HR Presentation - New Contract Policy
None
2018-06-21
Presentation on CERN's contract policy as of 2009. Topics covered include: staff member survey, work environment, career development, financial and social benefits, HR department activities and policy analysis.
ERIC Educational Resources Information Center
Peterson, Lorna
1994-01-01
Provides suggestions for incorporating multicultural diversity issues into the graduate library science curriculum. Topics discussed include questions of context; demographic shifts; creating curricular activities, including guest lecturers and encouraging behavioral as well as cognitive changes; and student responses, including student…
NASA Technical Reports Server (NTRS)
2002-01-01
Activities for the Airborne Oceanographic Lidar (AOL) and the SeaWiFs data analysis projects supported under NASA contract NAS5-99094 for the period of April 2002 to May 2002 are recorded. Topics covered include: data acquisition, data analysis, field activities and software development.
The Green Pages: Environmental Education Activities K-12.
ERIC Educational Resources Information Center
Clearing, 1990
1990-01-01
Presented are 20 science activities for students K-12. Topics include role playing, similarities between urban and forest communities, ecosystems, garbage, recycling, food production, habitats, insects, tidal zone, animals, diversity, interest groups, rivers, spaceship earth, ecological interactions, and the cost of recreation. (KR)
Production Systems. Laboratory Activities.
ERIC Educational Resources Information Center
Gallaway, Ann, Ed.
This production systems guide provides teachers with learning activities for secondary students. Introductory materials include an instructional planning outline and worksheet, an outline of essential elements, domains and objectives, a course description, and a content outline. The guide contains 30 modules on the following topics: production…
ERIC Educational Resources Information Center
School Library Media Activities Monthly, 1996
1996-01-01
Provides five fully developed library media activities designed for use with specific curriculum units in art, health and nutrition, mathematics, science, and social studies. Library media skills, objectives, grade levels, instructional roles, procedures, evaluation, and follow-up are described for each activity. Specific topics include aardvarks,…
NASA Technical Reports Server (NTRS)
Johnston, John; Mosier, Mark; Howard, Joe; Hyde, Tupper; Parrish, Keith; Ha, Kong; Liu, Frank; McGinnis, Mark
2004-01-01
This paper presents viewgraphs about structural analysis activities and integrated modeling for the James Webb Space Telescope (JWST). The topics include: 1) JWST Overview; 2) Observatory Structural Models; 3) Integrated Performance Analysis; and 4) Future Work and Challenges.
Communication Systems. Laboratory Activities.
ERIC Educational Resources Information Center
Sutherland, Barbara, Ed.
This communication systems guide provides teachers with learning activities for secondary students. Introductory materials include an instructional planning outline and worksheet, an outline of essential elements, a list of objectives, a course description, and a content outline. The guide contains 32 modules on the following topics: story…
Advanced aerodynamics and active controls. Selected NASA research
NASA Technical Reports Server (NTRS)
1981-01-01
Aerodynamic and active control concepts for application to commercial transport aircraft are discussed. Selected topics include in flight direct strike lightning research, triply redundant digital fly by wire control systems, tail configurations, winglets, and the drones for aerodynamic and structural testing (DAST) program.
Comprehensive Quantitative Model of Inner-Magnetosphere Dynamics
NASA Technical Reports Server (NTRS)
Wolf, Richard A.
2002-01-01
This report includes descriptions of papers, a thesis, and works still in progress which cover observations of space weather in the Earth's magnetosphere. The topics discussed include: 1) modelling of magnetosphere activity; 2) magnetic storms; 3) high energy electrons; and 4) plasmas.
Physics of non-Newtonian fluids and interdisciplinary relations (biology and criminology)
NASA Astrophysics Data System (ADS)
Holubova, R.
2018-03-01
The aim of the paper is the presentation of an interdisciplinary topic that allows applying content knowledge in physics, mathematics and biology in real life environment. Students use to play games and view crime scenes but in common they have little knowledge about the science used during crime scene investigation. In this paper the science background of blood spatter analysis is presented—the physics of non-Newtonian fluids, the biology of blood and mathematics—the measurement and calculation of the angle of inpact, the relationship between height and spatter diameter. This topic was choosen according to the analysis of interviews with secondary and high school learners realized at four schools in Moravia, Czech Republic. The topic can be taught at secondary schools so as at a higher level at high schools. Hands-on activities are included. The teaching strategy supports group work. The appropriateness and reasonableness of the topic was checked in the real teaching process and the activities have had a positive feedback.
Boikov, Dina A.; James, Kenneth D.; Bartizal, Ken; Sobel, Jack D.
2017-01-01
Background: The novel echinocandin CD101 has stability properties amenable to topical formulation for use in the treatment of acute vulvovaginal candidiasis (VVC) and recurrent VVC (RVVC). CD101 has demonstrated potent antifungal activity at pH 7, but assessment of its activity at the physiological pH of the vaginal environment is needed. Objectives: To evaluate the antifungal activity of CD101 against clinical VVC isolates of Candida spp., including azole-resistant strains, at pH 4. Methods: MIC values of CD101 and comparators (fluconazole, itraconazole, micafungin, caspofungin and anidulafungin) were assessed via broth microdilution. MIC assays were conducted at pH 7 and 4 after 24 and 48 h against a 108 VVC isolate panel of Candida spp., including Candida albicans (n = 60), Candida glabrata (n = 21), Candida parapsilosis (n = 14) and Candida tropicalis (n = 13). Results: Overall, MIC values of all drugs were slightly higher at pH 4 versus 7 and at 48 versus 24 h of incubation. CD101 MIC values typically exhibited ∼4-fold shifts at pH 4 and were not affected by azole susceptibility. C. parapsilosis susceptibility was the least affected at pH 4 and did not increase for most drugs. Conclusions: CD101 had potent activity against all Candida isolates tested, including azole-resistant strains. Although there was some reduction in activity at pH 4 versus 7, the resulting MIC values were still well below the intravaginal CD101 drug concentrations anticipated to be present following topical administration. These results support continued development of topical CD101 for the treatment of VVC/RVVC. PMID:28158577
Boikov, Dina A; Locke, Jeffrey B; James, Kenneth D; Bartizal, Ken; Sobel, Jack D
2017-05-01
The novel echinocandin CD101 has stability properties amenable to topical formulation for use in the treatment of acute vulvovaginal candidiasis (VVC) and recurrent VVC (RVVC). CD101 has demonstrated potent antifungal activity at pH 7, but assessment of its activity at the physiological pH of the vaginal environment is needed. To evaluate the antifungal activity of CD101 against clinical VVC isolates of Candida spp., including azole-resistant strains, at pH 4. MIC values of CD101 and comparators (fluconazole, itraconazole, micafungin, caspofungin and anidulafungin) were assessed via broth microdilution. MIC assays were conducted at pH 7 and 4 after 24 and 48 h against a 108 VVC isolate panel of Candida spp., including Candida albicans ( n = 60), Candida glabrata ( n = 21), Candida parapsilosis ( n = 14) and Candida tropicalis ( n = 13). Overall, MIC values of all drugs were slightly higher at pH 4 versus 7 and at 48 versus 24 h of incubation. CD101 MIC values typically exhibited ∼4-fold shifts at pH 4 and were not affected by azole susceptibility. C. parapsilosis susceptibility was the least affected at pH 4 and did not increase for most drugs. CD101 had potent activity against all Candida isolates tested, including azole-resistant strains. Although there was some reduction in activity at pH 4 versus 7, the resulting MIC values were still well below the intravaginal CD101 drug concentrations anticipated to be present following topical administration. These results support continued development of topical CD101 for the treatment of VVC/RVVC. © The Author 2017. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.
Marine and Environmental Studies Field Manual.
ERIC Educational Resources Information Center
Cranston School Dept., RI.
This laboratory manual was developed for a field-oriented high school oceanology program. The organization of the units includes a selection of supplementary activities to allow students to explore ocean studies in more depth. Included are 19 units. The units include biological oceanography, physical oceanography, and some social science topics. A…
The Road to Computer Literacy. Part V: Objectives and Activities for Grades 10-12.
ERIC Educational Resources Information Center
Bitter, Gary
1983-01-01
Presents computer-oriented activities in computer awareness and programing for students in grades 10-12. Intended for use by teachers of all disciplines, activities include such topics as prediction, interpretation and generalization of data, computer systems, PASCAL and PILOT programing, sampling techniques, computer survival, invasion of…
NASA Technical Reports Server (NTRS)
Grantier, David
2003-01-01
This paper presents viewgraphs on the development of the Weather Accident Prevention (WxAP) System architecture and Concept of Operation (CONOPS) activities. The topics include: 1) Background Information on System Architecture/CONOPS Activity; 2) Activity Work in Progress; and 3) Anticipated By-Products.
Teaching Writing Skills: Global Issues. Skills Series, Volume 3.
ERIC Educational Resources Information Center
Benegar, John
Social studies and language arts teachers can use these self-contained activities to teach writing skills to students in grades 6-12. Some of the activities have a global approach requiring students to write about topics such as human rights and cultural differences. Information provided for each activity includes an introduction, objectives, time…
Oceanography. Boy Scouts of America Merit Badge Series.
ERIC Educational Resources Information Center
Boy Scouts of America, Irving, TX.
Presented are various activities and projects intended to help Boy Scouts earn a merit badge in oceanography. Each project and/or activity is related to a requirement (objective) found in a list at the beginning of the booklet. Topic areas and/or related activities and projects include: (1) nature of oceanography (naming oceanography branches,…
Is cognitive science usefully cast as complexity science?
Van Orden, Guy; Stephen, Damian G
2012-01-01
Readers of TopiCS are invited to join a debate about the utility of ideas and methods of complexity science. The topics of debate include empirical instances of qualitative change in cognitive activity and whether this empirical work demonstrates sufficiently the empirical flags of complexity. In addition, new phenomena discovered by complexity scientists, and motivated by complexity theory, call into question some basic assumptions of conventional cognitive science such as stable equilibria and homogeneous variance. The articles and commentaries that appear in this issue also illustrate a new debate style format for topiCS. Copyright © 2011 Cognitive Science Society, Inc.
Pacheco, Natália Ramos; Pinto, Nícolas de Castro Campos; da Silva, Josiane Mello; Mendes, Renata de Freitas; da Costa, Juliana de Carvalho; Aragão, Danielle Maria de Oliveira; Castañon, Maria Christina Marques Nogueira; Scio, Elita
2014-01-01
Cecropia pachystachya is a species traditionally used in Brazil to treat inflammation. This work aims to evaluate the topical anti-inflammatory and antioxidant activities of the methanolic extract of C. pachystachya (CPM) and to perform its chemical fingerprint by HPLC-DAD. The topical anti-inflammatory activity was evaluated using the mouse models of acute ear inflammation induced by croton oil, arachidonic acid, capsaicin, EPP, phenol, and chronic inflammation induced by multiple application of croton oil. The in vitro antioxidant effect of CPM was investigated using DPPH, reducing power, β -carotene bleaching, and TBARS assays. HPLC analysis was performed to quantify the antioxidant phenolics orientin, isoorientin, and chlorogenic acid previously identified in CPM. CPM exhibited significant anti-inflammatory effect in the acute models, in some cases comparable to the reference drugs. Histopathological analysis showed a moderate chronic skin anti-inflammatory effect with decrease in vasodilation, edema, cell infiltration, and epidermal hyperproliferation. It also showed strong in vitro antioxidant activity. The contents of orientin, isoorientin, and chlorogenic acid were 66.5 ± 1.8, 118.8 ± 0.7, and 5.4 ± 0.2 µg/mg extract, respectively. The topical anti-inflammatory activity of CPM could be based on its antioxidant properties, although other effects are probably involved, including COX inhibition and other mechanisms.
ERIC Educational Resources Information Center
School Science Review, 1990
1990-01-01
Presented are 27 science activities for secondary school science instruction. Topic areas include microbiology, botany, biochemistry, genetics, safety, earthquakes, problem solving, electricity, heat, solutions, mechanics, quantum mechanics, flame tests, and molecular structure. (CW)
Workshops of the Fifth International Brain-Computer Interface Meeting: Defining the Future.
Huggins, Jane E; Guger, Christoph; Allison, Brendan; Anderson, Charles W; Batista, Aaron; Brouwer, Anne-Marie A-M; Brunner, Clemens; Chavarriaga, Ricardo; Fried-Oken, Melanie; Gunduz, Aysegul; Gupta, Disha; Kübler, Andrea; Leeb, Robert; Lotte, Fabien; Miller, Lee E; Müller-Putz, Gernot; Rutkowski, Tomasz; Tangermann, Michael; Thompson, David Edward
2014-01-01
The Fifth International Brain-Computer Interface (BCI) Meeting met June 3-7 th , 2013 at the Asilomar Conference Grounds, Pacific Grove, California. The conference included 19 workshops covering topics in brain-computer interface and brain-machine interface research. Topics included translation of BCIs into clinical use, standardization and certification, types of brain activity to use for BCI, recording methods, the effects of plasticity, special interest topics in BCIs applications, and future BCI directions. BCI research is well established and transitioning to practical use to benefit people with physical impairments. At the same time, new applications are being explored, both for people with physical impairments and beyond. Here we provide summaries of each workshop, illustrating the breadth and depth of BCI research and high-lighting important issues for future research and development.
ERIC Educational Resources Information Center
Blackburn, Mary Ellen; Hall, Doris N.
Materials are provided for a consumer education activity designed to help teenagers make knowledgeable, rational decisions when purchasing goods and services. A student manual describes how the activity--a consumer judging contest--works. Information is provided on how consumers make decisions. Topics include: needs versus wants; sources of…
ERIC Educational Resources Information Center
NatureScope, 1985
1985-01-01
Provides (1) background information on global winds, air masses, fronts, and pressure systems; (2) five activities on this topic; and (3) a ready-to-copy coloring page and worksheet. Each activity includes an objective, list of materials needed, recommended age level(s), subject area(s), and instructional strategies. (JN)
Instructional Analysis for Health Occupations.
ERIC Educational Resources Information Center
East Texas State Univ., Commerce. Occupational Curriculum Lab.
This instructional analysis centers on identifying the skills, related knowledge, teacher activities, and student activities that are central to teaching various topics included in the core curriculum for health occupations courses. Addressed in the volume are the following instructional areas: first aid; medical terminology; medical asepsis;…
The Green Pages: Environmental Education Activities K-12.
ERIC Educational Resources Information Center
Clearing, 1991
1991-01-01
Presented are 38 environmental education activities for grades K-12. Topics include seed dispersal, food chains, plant identification, sizes and shapes, trees, common names, air pollution, recycling, temperature, litter, water conservation, photography, insects, urban areas, diversity, natural cycles, rain, erosion, phosphates, human population,…
Electricity/Electronics Systems. Laboratory Activities.
ERIC Educational Resources Information Center
Sutherland, Barbara, Ed.
This electricity/electronics guide provides teachers with learning activities for secondary students. Introductory materials include an instructional planning outline and worksheet, an outline of essential elements, a list of objectives, a course description, and a content outline. The guide contains 35 modules on the following topics: electrical…
The Green Pages: Environmental Education Activities K-12.
ERIC Educational Resources Information Center
Clearing, 1990
1990-01-01
Presented are 37 environmental science activities for students in grades K-12. Topics include water pollution, glaciers, protective coloration, shapes in nature, environmental impacts, recycling, creative writing, litter, shapes found in nature, color, rain cycle, waste management, plastics, energy, pH, landfills, runoff, watersheds,…
ERIC Educational Resources Information Center
Alaska State Dept. of Education, Juneau. Div. of Adult and Vocational Education.
This guide contains instructional materials to aid business education teachers in teaching business skills in Alaska secondary schools. The materials include five units covering the following topics: human relations as a separate unit and as integrated into other daily activities such as planning and organizing work activities and grooming,…
The Living Ocean. SeaWiFS: Studying Ocean Color from Space. Teacher's Guide with Activities
NASA Technical Reports Server (NTRS)
1994-01-01
This educational document, designed for grades 9 to 10, discusses the observation of oceans from space. Topics covered include ocean color, the role of phytoplankton, the carbon cycle, and the greenhouse effect. Activities and discussion questions are presented.
ERIC Educational Resources Information Center
School Library Media Activities Monthly, 1992
1992-01-01
Provides fully developed library media activities for elementary and middle school students, most of which are designed to be used in connection with specific curriculum units. Topics covered include art; reading/language arts, including fiction, point of view, storytelling, and dictionary skills; science; and social studies. (LRW)
ERIC Educational Resources Information Center
Naturescope, 1987
1987-01-01
Contains a glossary of terms related to endangered species and lists reference books, children's books, audio-visual materials, software, and activity sources on the topics. Also identifies wildlife laws and explains what they mean. An index of issues of "Ranger Rick," which includes articles on endangered species, is included. (ML)
ERIC Educational Resources Information Center
Awkerman, Gary L.
This publication is designed for use in standard science curricula to develop oceanologic manifestations of certain science topics. Included are teacher guides, student activities, and demonstrations to impart ocean science understanding, specifically, aspects of marine ecology, to high school students. The course objectives include the ability of…
Integrated Flywheel Technology, 1983
NASA Technical Reports Server (NTRS)
Keckler, C. R. (Editor); Rodriguez, G. E. (Editor); Groom, N. J. (Editor)
1983-01-01
Topics of discussion included: technology assessment of the integrated flywheel systems, potential of system concepts, identification of critical areas needing development and, to scope and define an appropriate program for coordinated activity.
ERIC Educational Resources Information Center
School Science Review, 1990
1990-01-01
Presented are 29 science activities for secondary school science instruction. Topic areas include botany, genetics, biochemistry, anatomy, entomology, molecular structure, spreadsheets, chemistry, mechanics, astronomy, relativity, aeronautics, instrumentation, electrostatics, quantum mechanics, and laboratory interfacing. (CW)
Lungu, Codrin; Considine, Elaine; Zahir, Sana; Ponsati, Berta; Arrastia, Silvia; Hallett, Mark
2016-01-01
Background Injectable botulinum neurotoxin (BoNT) is the principal effective treatment for blepharospasm (BSP). This trial explores the safety and efficacy of topical Acetyl Hexapeptide-8 (AH8), a competitive SNAP25 inhibitor, as a potential new therapy in BSP. Methods Double-blind, placebo-controlled, randomized trial of daily topical application of AH8 in 24 patients with BSP. The primary outcome was time to return to baseline Jankovic Rating Scale (JBRS) after a BoNT injection simultaneously with initiation of AH8. Patients displaying a strictly regular pattern of response to 3-monthly injections of BoNT were included. Results There were no significant adverse events. There was a trend for longer time until return to baseline JBRS after injection in the active group compared to placebo (3.7 vs 3.0 months), and for better scores in the active group. One third (4/12) of the patients in the active group had a significant extension of symptom control after BoNT (range: 3.3-7.1 months). Conclusions Topical AH8 is safe and promising for extending the duration of action of BoNT therapy for BSP. PMID:23146065
Contracts and Management Services FY 1996 Site Support Program Plan: WBS 6.10.14. Revision 1
DOE Office of Scientific and Technical Information (OSTI.GOV)
Knoll, J.M. Jr.
1995-09-01
This is the Contracts and Management Services site support program plan for the US DOE Hanford site. The topics addressed in the program plan include a mission statement, program objectives, planning assumptions, program constraints, work breakdown structure, milestone list, milestone description sheets, and activity detail including cost accounting narrative summary, approved funding budget, and activity detailed description.
Seventh BES (Basic Energy Sciences) catalysis and surface chemistry research conference
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1990-03-01
Research programs on catalysis and surface chemistry are presented. A total of fifty-seven topics are included. Areas of research include heterogeneous catalysis; catalysis in hydrogenation, desulfurization, gasification, and redox reactions; studies of surface properties and surface active sites; catalyst supports; chemical activation, deactivation; selectivity, chemical preparation; molecular structure studies; sorption and dissociation. Individual projects are processed separately for the data bases. (CBS)
NASA Technical Reports Server (NTRS)
2002-01-01
This report outlines the activities of the GLOBE (Global Learning and Observations to Benefit the Environment) Train-the-Trainer Workshop. Educators were introduced to the GLOBE protocols for Atmosphere, Hydrology, Soil and Land Cover. These protocols included measurement of pH, temperature, precipitation, salinity, and soil moisture content. Each topic included implementation plans and learning activities.
Low Budget Biology: Genetics Unit.
ERIC Educational Resources Information Center
Wartski, Bert; Wartski, Lynn Marie
Some concepts in genetics are difficult for many students to understand. This document provides hands-on, cost efficient, fun activities for students to help them better understand abstract concepts in genetics. Each activity includes: purpose, introduction, materials, procedures, results and conclusion. Some of the topics explored are: (1)…
Summaries of "You Do It" Activities Presented at the 1978 SASTA Conference in the Riverland.
ERIC Educational Resources Information Center
Walsh, Terry
1980-01-01
Summarizes "you do it" activities presented at the 1978 South Australian Science Teachers Association Conference. Topics include microscope use and maintenance, chemical slide cells, chemical models, sound waves, microwaves, astronomy, plant keys, reading geological maps, and natural dye processes. (DS)
Microgravity: Teacher's Guide with Activities for Physical Science.
ERIC Educational Resources Information Center
Vogt, Gregory L.; Wargo, Michael J.
This teacher's guide to microgravity contains 16 student science activities with full background information to facilitate an understanding of the concepts of microgravity for teachers and students. Topics covered in the background sections include the definitions of gravity and microgravity, creating microgravity, the fluid state, combustion…
Flight. Science Series Grades 4, 5, 6.
ERIC Educational Resources Information Center
Frensch, Helen
The activities in this book are designed to reinforce the elementary concepts of flight. General background information, suggested activities, questions for discussion, and answers are provided. Twenty-eight reproducible worksheets are contained in this guide. Topics include: hot air balloons, the physics of flight, air resistance, airplane…
CFD Modeling Activities at the NASA Stennis Space Center
NASA Technical Reports Server (NTRS)
Allgood, Daniel
2007-01-01
A viewgraph presentation on NASA Stennis Space Center's Computational Fluid Dynamics (CFD) Modeling activities is shown. The topics include: 1) Overview of NASA Stennis Space Center; 2) Role of Computational Modeling at NASA-SSC; 3) Computational Modeling Tools and Resources; and 4) CFD Modeling Applications.
Sport for All. Exercise and Health.
ERIC Educational Resources Information Center
Astrand, Per-Olof
This booklet is divided into seven sections that include the following topics: (a) physical performance, (b) adaptation to inactivity and activity, (c) physiological and medical motives for regular physical activity, (d) training, (e) physical fitness for everyday life, and (f) testing physical fitness and condition. Section one discusses energy…
ERIC Educational Resources Information Center
Ekachai, Daradirek
Noting that most basic communication textbooks do not include a cultural diversity component, this paper presents 14 experiential exercises aimed to integrate the multicultural issues related to interpersonal communication topics. The various experiential activities are adapted from intercultural communication textbooks, cross-cultural training…
ERIC Educational Resources Information Center
Doty, Robert
1995-01-01
Features Internet sites that are sources for lesson plans, materials, group discussion topics, activities, test questions, computer software, and videos for K-12 education. Resources highlighted include CNN Newsroom, KidLink, and AskERIC. (AEF)
Space Station Displays and Controls Technology Evolution
NASA Technical Reports Server (NTRS)
Blackburn, Greg C.
1990-01-01
Viewgraphs on space station displays and controls technology evolution are presented. Topics covered include: a historical perspective; major development objectives; current development activities; key technology areas; and technology evolution issues.
Lopez Energy Alternatives project. Final report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Forbes, R.B.
1985-01-01
The activities reported include: purchase of books and periodical subscriptions on energy-related topics for a community library; organization of energy-related workshops; and monitoring of solar radiation and wind. (LEW)
Transdermal patches: history, development and pharmacology
Pastore, Michael N; Kalia, Yogeshvar N; Horstmann, Michael; Roberts, Michael S
2015-01-01
Transdermal patches are now widely used as cosmetic, topical and transdermal delivery systems. These patches represent a key outcome from the growth in skin science, technology and expertise developed through trial and error, clinical observation and evidence-based studies that date back to the first existing human records. This review begins with the earliest topical therapies and traces topical delivery to the present-day transdermal patches, describing along the way the initial trials, devices and drug delivery systems that underpin current transdermal patches and their actives. This is followed by consideration of the evolution in the various patch designs and their limitations as well as requirements for actives to be used for transdermal delivery. The properties of and issues associated with the use of currently marketed products, such as variability, safety and regulatory aspects, are then described. The review concludes by examining future prospects for transdermal patches and drug delivery systems, such as the combination of active delivery systems with patches, minimally invasive microneedle patches and cutaneous solutions, including metered-dose systems. PMID:25560046
Spinoff 2008: 50 Years of NASA-Derived Technologies (1958-2008)
NASA Technical Reports Server (NTRS)
2008-01-01
NASA Technology Benefiting Society subject headings include: Health and Medicine, Transportation, Public Safety, Consumer, Home and Recreation, Environmental and Agricultural Resources, Computer Technology, and Industrial Productivity. Other topics covered include: Aeronautics and Space Activities, Education News, Partnership News, and the Innovative Partnership Program.
A Holistic Approach to Water Ecology.
ERIC Educational Resources Information Center
Koyama, Keith
1980-01-01
Outlined is a water ecology unit included within a one-semester field biology course for upper level high school students. Activities described include a visit to a water treatment plant, an abiotic stream study, a biotic stream study, interactions and questioning topics, and individual projects. (CS)
Population Education Accessions Lists, July-December 1986.
ERIC Educational Resources Information Center
United Nations Educational, Scientific, and Cultural Organization, Bangkok (Thailand). Regional Office for Education in Asia and the Pacific.
Part I of this resource guide contains listings of instructional materials, computer-assisted instructions, classroom activities and teaching methods. Part II deals with the knowledge base of population education. These publications are divided into 11 topics including: (1) demography; (2) documentation; (3) education (including environmental,…
The Minnesota Experience with Family-Centered Early Childhood Programs.
ERIC Educational Resources Information Center
Engstrom, Lois
1988-01-01
The author describes Minnesota's Early Childhood Family Education program for all children from birth to kindergarten and their parents. Topics include the types of activities each local program undertakes, administration and planning, and financing. A list of important program attributes is included. (CH)
French-Canadians, Acadians and the French in New England. A Learning Activity Packet.
ERIC Educational Resources Information Center
Maine Univ., Orono. New England - Atlantic Provinces - Quebec Center.
The history of the French-Canadians from their beginnings to the present time is the topic of this Learning Activity Packet (LAP). Designed to acquaint students with the French, Canada's earliest permanent settlers following the Indians, the unit is divided into six objectives which include learning activities for each. Students are expected to…
ERIC Educational Resources Information Center
Stone, Sally F.
This instructional guide contains 16 activities designed to help teachers familiarize their students with the forest resources of Illinois. Each activity is ready to be copied and given to students. Topics of the activities, which vary in format, include: an overview of past and present Illinois forests; organization and mechanics of a forest…
Elementary Anatomy: Activities Designed to Teach Preschool Children about the Human Body
ERIC Educational Resources Information Center
Raven, Sara
2016-01-01
Studies show that children may not be able to conceptualize some of the topics associated with anatomy, including internal organs and involuntary muscles, because the concepts are too abstract and are not easily visualized. Thus, this article presents activities that incorporate a variety of models and hands-on activities designed to provide…
The Wonder of Wolves: A Story & Activities. Revised Edition. The Wonder Series.
ERIC Educational Resources Information Center
Robinson, Sandra Chisholm
This curriculum guide is all about wolves and provides information through the telling of a story about wolves and their history and folklore. The 14 activities contained in this guide employ an interdisciplinary approach and use mazes, puzzles, model-building, and board games to motivate students. Activity topics include building a wolf,…
Cereal Box Design: An Interdisciplinary Graphics Activity
ERIC Educational Resources Information Center
Fitzgerald, Mike; Tsosie, Teri
2012-01-01
The cereal box design activity is intriguing both for its simplicity and the resourcefulness that it can generate in young people. Also, it lends itself to a variety of curriculums. It covers both consumerism and Design for the Environment (DfE) concepts broadly and in depth. The activity introduces a wide range of topics. They include graphic…
ERIC Educational Resources Information Center
Fraknoi, Andrew, Ed.; Schatz, Dennis, Ed.
The goal of this resource notebook is to provide activities selected by astronomers and classroom teachers, comprehensive resource lists and bibliographies, background material on astronomical topics, and teaching ideas from experienced astronomy educators. Activities are grouped into several major areas of study in astronomy including lunar…
CTOL Transport Technology, 1978. [conferences
NASA Technical Reports Server (NTRS)
1978-01-01
Technology associated with advanced conventional takeoff and landing transport aircraft is discussed. Topics covered include: advanced aerodynamics and active controls; operations and safety; and advanced systems. Emphasis is placed on increased energy efficiency.
ERIC Educational Resources Information Center
School Science Review, 1982
1982-01-01
Presents procedures, demonstrations, activities, and teaching suggestions on topics appropriate for middle school science including a simple electrolysis cell, conversion factors, energy, solubilities of salts, condensers, and a worksheet for studying coppice woodlands. (DC)
Advanced control technology and its potential for future transport aircraft
NASA Technical Reports Server (NTRS)
1976-01-01
The topics covered include fly by wire, digital control, control configured vehicles, applications to advanced flight vehicles, advanced propulsion control systems, and active control technology for transport aircraft.
ERIC Educational Resources Information Center
Thurman, Shirley; And Others
1988-01-01
Describes 36 science activities. Topics include: osmosis, fermentation, anhydrobiotic organisms, breathing monitors, trypsin, weeds, amyloplasts, electrolysis, polarimeters, ethene ripening of fruit, colorimetry, diffusion, redox reactions, equilibria, acid-base relationships, electricity, power, resonance, measurement, parallax, amplifiers,…
The Yucatan miniature swine as an in vivo model for screening skin depigmentation.
Nair, X; Tramposch, K M
1991-12-01
The usefulness of the Yucatan miniature pig as a screen for skin dipigmenting activity by topical application was evaluated with standard compounds. This is a naturally occurring breed of swine with light brown to dark brown skin that is relatively hairless. The skin morphology, including the pattern of pigment distribution, in this breed of swine closely resembles the human skin. Test compounds examined in this study included the three standard compounds with known clinical depigmenting activity, hydroquinone (HQ), 4-hydroxyanisole (4HA) and tert-butyl catechol (TBC), each at a 5% concentration. Test materials in 25 microliters of propylene glycol/ethanol (50:50) were applied topically twice daily, 7 days a week for 90 days to test sites on each side of the dorsal mid-line. Test sites were graded weekly for variation in pigmentation and local irritation. After 90 days of test material application, skin biopsies of the test sites were taken for histological evaluation. Topical application of HQ, 4HA and TBC promoted marked skin depigmentation which was substantiated by reductions of pigment and melanocytes observed on microscopic examination. While both HQ and TBC produced marked local irritation, 4HA was only mildly irritating. These results suggest that the Yucatan pig, could be a potentially useful model for screening compounds with skin depigmenting activity.
2013-01-01
Background The number of chronically ill patients increases every year. This is partly due to an unhealthy lifestyle. However, the frequency and quality of (evidence-based) health promotion activities conducted by Dutch general practitioners (GPs) and practice nurses (PNs) are limited. The aim of this pilot study was to explore which lifestyle interventions Dutch GPs and PNs carry out in primary care, which barriers and facilitators can be identified and what main topics are with respect to attitudes towards health promoting activities. These topic areas will be identified for a future, larger scale study. Method This qualitative study consisted of 25 semi-structured interviews with sixteen GPs and nine PNs. ATLAS.ti was used to analyse the transcripts of the interviews. Results All GPs and PNs said they discuss lifestyle with their patients. Next to this, GPs and PNs counsel patients, and/or refer them to other disciplines. Only few said they refer patients to specific lifestyle programs or interventions in their own practice or in the neighbourhood. Several barriers and facilitators were identified. The main topics as barriers are: a lack of patients’ motivation to make lifestyle changes, insufficient reimbursement, a lack of proven effectiveness of interventions and a lack of overview of health promoting programs in their neighbourhood. The most cited facilitators are availability of a PN, collaboration with other disciplines and availability of interventions in their own practice. With respect to attitudes, six different types of GPs were identified reflecting the main topics that relate to attitudes, varying from ‘ignorer’ to ‘nurturer’. The topics relating to PNs attitudes towards health promotion activities, were almost unanimously positive. Conclusion GPs and PNs all say they discuss lifestyle issues with their patients, but the health promotion activities that are organized in their practice vary. Main topics that hinder or facilitate implementation are identified, including those that relate to attitudes of GPs and PNs. PMID:23394162
Exploring the Universe. Science Series Grades 4, 5, 6.
ERIC Educational Resources Information Center
Giessow, Jean; Giessow, Fred
The activities in this book are designed to reinforce elementary concepts in the study of the universe. General background information, suggested activities, questions for discussion, and answers are provided. Twenty-eight reproducible worksheets are contained in this guide. Topics include: the solar system, orbits, planets, the sun, forces in…
Algebra. A Guidebook for Teaching.
ERIC Educational Resources Information Center
Goodman, Terry A.; And Others
This book provides a general framework for organizing the instructional program in algebra. For each topic, a general approach for instruction, together with specific strategies, activities, and resources that can be used daily, are provided. Also included are worksheet pages that can be used with students. Most activities provide for student…
Nutrition. Learning Activity Package.
ERIC Educational Resources Information Center
Lee, Carolyn
This learning activity package on nutrition is one of a series of 12 titles developed for use in health occupations education programs. Materials in the package include objectives, a list of materials needed, a list of definitions, information sheets, reviews (self evaluations) of portions of the content, and answers to reviews. These topics are…
Shock & Anaphylactic Shock. Learning Activity Package.
ERIC Educational Resources Information Center
Hime, Kirsten
This learning activity package on shock and anaphylactic shock is one of a series of 12 titles developed for use in health occupations education programs. Materials in the package include objectives, a list of materials needed, information sheets, reviews (self evaluations) of portions of the content, and answers to reviews. These topics are…
Effluent treatment for nuclear thermal propulsion ground testing
NASA Technical Reports Server (NTRS)
Shipers, Larry R.
1993-01-01
The objectives are to define treatment functions, review concept options, discuss PIPET effluent treatment system (ETS), and outline future activities. The topics covered include the following: reactor exhaust; effluent treatment functions; effluent treatment categories; effluent treatment options; concept evaluation; PIPETS ETS envelope; PIPET effluent treatment concept; and future activities.
How to Individualize Mathematics Successfully: With Materials for Implementation.
ERIC Educational Resources Information Center
Vinskey, Mildred L.
Presented is a method for individualizing mathematics which utilizes the "Learning Activities Package" (LAP). LAP is a self-contained unit based on specific behavioral objectives which contains a pretest, a posttest, examples, explanations, and activities. The topics covered include but are not limited to: multiplication and division by powers of…
ERIC Educational Resources Information Center
Durkin, Lisa Lyons, Ed.
1998-01-01
This document is comprised of the six issues of volume 19 of "First Teacher," a periodical providing helpful activity ideas and information on child development for early childhood teachers and caregivers. The major topics for each themed issue are as follows: (1) Exploring Letters and Numbers, including flannel board activities, and number rhymes…
Seventh National Conference on Physical Activity for the Exceptional Individual.
ERIC Educational Resources Information Center
Los Angeles County Superintendent of Schools, CA. Div. of Special Education.
A variety of physical activities and their applications to special education situations are presented and discussed in this collection of papers. Topics include--games for exceptional populations, mime and movement, behavioral management techniques, motor development programs for the handicapped, teacher and student motivation, yoga for the…
The Ideological Basis of Teacher Organization or Why We Do What We Do.
ERIC Educational Resources Information Center
Sutton, James H.
An attempt to explain the behavior of local, state and national teacher organizations by reference to the ideological basis for their activities, this paper links professionalism and excellence to previous organizational activity and demonstrates their continuity. Significant topics include the professionalization of teaching amid societal…
For the Classroom--The Five Signs of Death: Cold Water Camouflage.
ERIC Educational Resources Information Center
Lin, Leslie
1981-01-01
Outlines a classroom science activity suitable for elementary through adult levels demonstrating that coldwater submergence may cause some people to appear dead when they are not. Includes a description of several activities which exhibit the signs of coldwater camouflage, materials needed, and discussion topics. (DS)
Student Activity Guide for "Business in an Information Economy."
ERIC Educational Resources Information Center
Graf, David; And Others
The 20 chapters of this student activity guide provide study guides (key terms and concepts reviews), projects, cases for analyses, and self-assessment exercises for business and career education classes. Topics covered include the following: business winners (entrepreneurship); growth of the U.S. economy, the basics of economics, comparing…
JPL space station telerobotic engineering prototype development FY 91 status/achievements
NASA Technical Reports Server (NTRS)
Zimmerman, Wayne
1991-01-01
The topics covered are presented in view graph form and include: (1) streamlining intravehicular activity (IVA) teleoperation activities on the Space Station Freedom (SSF); (2) enhancing SSF utilization during the man-tended phase; (3) telerobotic ground remote operations (TGRO); and (4) advanced telerobotics system technology (shared control).
Volcanology by Courier: Science in Stamps.
ERIC Educational Resources Information Center
Glenn, William H.
1981-01-01
Summarized are five activities involving collection of postage stamps picturing volcanoes or related scenes for use as part of or at the conclusion of the study of volcanoes. Activity topics include volcanic features, location of volcanoes, related land features where volcanoes are not located, and making one's own volcano stamps. (DS)
ERIC Educational Resources Information Center
NatureScope, 1985
1985-01-01
Provides (1) background information showing how the sun, earth, air, and water work together to create weather; (2) six activities on this topic; and (3) a ready-to-copy coloring page on the water cycle. Each activity includes an objective, list of materials needed, recommended age level(s), subject area(s), and instructional strategies. (JN)
ERIC Educational Resources Information Center
NatureScope, 1986
1986-01-01
Provides: (1) background information on how forests are managed and some of the problems facing forests around the world; (2) three activities dealing with these topics; and (3) three ready-to-copy pages for student use. Activities include an objective, recommended age level(s), recommended subject area(s), list of materials needed, and…
WOWBugs: New Life for Life Science.
ERIC Educational Resources Information Center
Matthews, Robert W.; And Others
This book of life science activities introduces a new experimental animal--the WOWBug, "Melittobia digitata"--that is commonly found in nature but has never before been used in the precollege classroom. It includes 20 activities and experiments for grades 5-12, that cover topics from basic orientation to ecological interactions, from physical…
Grooming. Learning Activity Package.
ERIC Educational Resources Information Center
Stark, Pamela
This learning activity package on grooming for health workers is one of a series of 12 titles developed for use in health occupations education programs. Materials in the package include objectives, a list of materials needed, information sheets, reviews (self evaluations) of portions of the content, and answers to reviews. These topics are…
Science through Children's Literature: An Integrated Approach.
ERIC Educational Resources Information Center
Butzow, Carol M.; Butzow, John W.
1990-01-01
Discussed is a way to develop an integrated unit based on a fictional book. An example for constructing a unit is included as well as activities from units that consider birds, volcanoes, and measurement. Each unit contains a summary, topic areas, content-related words, activities, related books and references. (KR)
Workshops of the Fifth International Brain-Computer Interface Meeting: Defining the Future
Huggins, Jane E.; Guger, Christoph; Allison, Brendan; Anderson, Charles W.; Batista, Aaron; Brouwer, Anne-Marie (A.-M.); Brunner, Clemens; Chavarriaga, Ricardo; Fried-Oken, Melanie; Gunduz, Aysegul; Gupta, Disha; Kübler, Andrea; Leeb, Robert; Lotte, Fabien; Miller, Lee E.; Müller-Putz, Gernot; Rutkowski, Tomasz; Tangermann, Michael; Thompson, David Edward
2014-01-01
The Fifth International Brain-Computer Interface (BCI) Meeting met June 3–7th, 2013 at the Asilomar Conference Grounds, Pacific Grove, California. The conference included 19 workshops covering topics in brain-computer interface and brain-machine interface research. Topics included translation of BCIs into clinical use, standardization and certification, types of brain activity to use for BCI, recording methods, the effects of plasticity, special interest topics in BCIs applications, and future BCI directions. BCI research is well established and transitioning to practical use to benefit people with physical impairments. At the same time, new applications are being explored, both for people with physical impairments and beyond. Here we provide summaries of each workshop, illustrating the breadth and depth of BCI research and high-lighting important issues for future research and development. PMID:25485284
Research and technology of the Langley Research Center
NASA Technical Reports Server (NTRS)
1980-01-01
Descriptions of the research and technology activities at the Langley Research Center are given. Topics include laser development, aircraft design, aircraft engines, aerodynamics, remote sensing, space transportation systems, and composite materials.
ERIC Educational Resources Information Center
Wolf, Lori; And Others
1994-01-01
Offers 11 classroom tips from teachers for a variety of activities, including fictional movie reviews, haiku writing, questions to develop student journals, handouts, rewriting stories, and a "dirty trick" to get better research topics. (SR)
LSA: Low-cost Solar Array project
NASA Technical Reports Server (NTRS)
1978-01-01
Topics discussed include silicon material processing; large-area silicon sheet development; encapsulation materials testing and development; project engineering and operations activities, and manufacturing techniques. The steps taken to integrate these efforts, are described.
Excerpt from a Forthcoming Book. The Ocean Book: Dive In--The Beginning of Your Ocean Study.
ERIC Educational Resources Information Center
Science Activities, 1989
1989-01-01
Six activities complete with reproducible worksheets are presented. Materials and procedures for each are listed. Answers to the quiz and crossword puzzle are included. Topics include the water cycle, the world's oceans, the ocean floor, and fish. (CW)
Teaching through Trade Books: That Was Then, This Is Now
ERIC Educational Resources Information Center
Royce, Christine Anne
2015-01-01
This column includes activities inspired by children's literature. When learning about a topic, scientists refer to documents from past researchers. This month's trade books include nonfiction and historical fiction selections that help to demonstrate similarities and differences "then and now" while incorporating engineering design…
ERIC Educational Resources Information Center
Ohio State Univ., Columbus. Cooperative Extension Service.
Seven activity guides, evaluation sheet, and club scoresheet have been prepared for Ohio 4-H clubs' litter education program. Topics of the seven activity guides include: (1) general guidelines and types of activities; (2) little known facts about waste/litter; (3) guidelines for a walking tour; (4) fact sheet (questionnaire) related to garbage;…
Activities of the Population Centre during 1979-80: a retrospect.
Talwar, P P
1980-01-01
Activities of the Population Center in Lucknow are described. Studies designed to identify factors hindering the progress of the family welfare program are of 4 types. 1) Studies of operational and managerial aspects of the family welfare program service units include work on such topics as the determinants of effectiveness of subcenters in Uttar Pradesh, standardization of materials at rural service centers, factors affecting utilization and performance of primary health centers and subcenters, and effectiveness of auxiliary nurse midwives in delivering maternal and child health services. 2) Studies of effectiveness of program services include such topics as attitude toward vasectomy during the Emergency Period, collection of vital statistics by Community Health Volunteers, and comparisons of Lippes Loop insertions by doctors and paramedics. 3) Studies of education and communication activities include research into mass radio listening and newspaper reading habits and use of local first aid workers to motivate family planning acceptors. 4) Studies of involvement of different organizations in family welfare activities. Another group of studies conducted at the center was designed to evaluate the impact of the India Population Project and included surveys and analysis of secondary data. Population Center collaboration with other organizations and participation in professional meetings is also described, as is the proposed work for 1980-81.
The utilization of nonterrestrial materials. [resources for solar power satellite construction
NASA Technical Reports Server (NTRS)
1981-01-01
The development of research and technology programs on the user of nonterrestrial materials for space applications was considered with emphasis on the space power satellite system as a model of large space systems for which the use of nonterrestrial materials may be economically viable. Sample topics discussed include the mining of raw materials and the conversion of raw materials into useful products. These topics were considered against a background of the comparative costs of using terrestrial materials. Exploratory activities involved in the preparation of a nonterrestrial materials utilization program, and the human factors involved were also addressed. Several recommendations from the workshop are now incorporated in NASA activities.
Development of active learning modules in pharmacology for small group teaching.
Tripathi, Raakhi K; Sarkate, Pankaj V; Jalgaonkar, Sharmila V; Rege, Nirmala N
2015-01-01
Current teaching in pharmacology in undergraduate medical curriculum in India is primarily drug centered and stresses imparting factual knowledge rather than on pharmacotherapeutic skills. These skills would be better developed through active learning by the students. Hence modules that will encourage active learning were developed and compared with traditional methods within the Seth GS Medical College, Mumbai. After Institutional Review Board approval, 90 second year undergraduate medical students who consented were randomized into six sub-groups, each with 15 students. Pre-test was administered. The three sub-groups were taught a topic using active learning modules (active learning groups), which included problems on case scenarios, critical appraisal of prescriptions and drug identification. The remaining three sub-groups were taught the same topic in a conventional tutorial mode (tutorial learning groups). There was crossover for the second topic. Performance was assessed using post-test. Questionnaires with Likert-scaled items were used to assess feedback on teaching technique, student interaction and group dynamics. The active and tutorial learning groups differed significantly in their post-test scores (11.3 ± 1.9 and 15.9 ± 2.7, respectively, P < 0.05). In students' feedback, 69/90 students had perceived the active learning session as interactive (vs. 37/90 students in tutorial group) and enhanced their understanding vs. 56/90 in tutorial group), aroused intellectual curiosity (47/90 students of active learning group vs. 30/90 in tutorial group) and provoked self-learning (41/90 active learning group vs. 14/90 in tutorial group). Sixty-four students in the active learning group felt that questioning each other helped in understanding the topic, which was the experience of 25/90 students in tutorial group. Nevertheless, students (55/90) preferred tutorial mode of learning to help them score better in their examinations. In this study, students preferred an active learning environment, though to pass examinations, they preferred the tutorial mode of teaching. Further efforts are required to explore the effects on learning of introducing similar modules for other topics.
Third European Stroke Science Workshop.
Dichgans, Martin; Planas, Anna M; Biessels, Geert Jan; van der Worp, Bart; Sudlow, Cathie; Norrving, Bo; Lees, Kennedy; Mattle, Heinrich P
2016-07-01
Lake Eibsee, Garmisch-Partenkirchen, November 19 to 21, 2015: The European Stroke Organization convened >120 stroke experts from 27 countries to discuss latest results and hot topics in clinical, translational, and basic stroke research. Since its inception in 2011, the European Stroke Science Workshop has become a cornerstone of European Stroke Organization's academic activities and major highlight for researchers in the field. Participants include stroke researchers at all career stages who convene for plenary lectures and discussions, thus facilitating crosstalk among researchers from different fields. As in previous years, the workshop was organized into 7 scientific sessions each focusing on a major research topic. All sessions started with a keynote lecture that provided an overview on current developments and set the scene for the following presentations. The latter were short focused talks on a timely topic and included the most recent findings, including unpublished data. A new element at this year's meeting was a hot topic session in which speakers had to present a provocative concept or update sharply within 5 minutes. In the following, we summarize the key contents of the meeting. The program is provided in the online-only Data Supplement. © 2016 American Heart Association, Inc.
ERIC Educational Resources Information Center
School Science Review, 1985
1985-01-01
Presents 23 experiments, activities, field projects and computer programs in the biological and physical sciences. Instructional procedures, experimental designs, materials, and background information are suggested. Topics include fluid mechanics, electricity, crystals, arthropods, limpets, acid neutralization, and software evaluation. (ML)
Advanced Thermionic Technology Program
NASA Technical Reports Server (NTRS)
1977-01-01
Topics include surface studies (surface theory, basic surface experiments, and activation chamber experiments); plasma studies (converter theory and enhanced mode conversion experiments); and component development (low temperature conversion experiments, high efficiency conversion experiments, and hot shell development).
ERIC Educational Resources Information Center
School Science Review, 1983
1983-01-01
Presents background information, laboratory procedures, classroom materials/activities, and chemistry experiments. Topics include sublimation, electronegativity, electrolysis, experimental aspects of strontianite, halide test, evaluation of present and future computer programs in chemistry, formula building, care of glass/saturated calomel…
Rethinking the Holidays. Teacher's Resources.
ERIC Educational Resources Information Center
Porter, Priscilla H.
1993-01-01
Maintains that holidays provide opportunities for teaching about history and cultural diversity. Presents a bibliographic essay of recommended resources for elementary teachers on this topic. Materials include reading resources, activity books, and audiovisual materials. (CFR)
Heterodyne systems and technology, part 1. [conferences
NASA Technical Reports Server (NTRS)
1980-01-01
Various aspects of optical heterodyning are considered. Topics covered heterodyning throughout the electromagnetic spectrum including detectors, local oscillators, tunable diode lasers, astronomical systems, and environmental sensors, with both active and passive systems represented.
Pacheco, Natália Ramos; Pinto, Nícolas de Castro Campos; Mendes, Renata de Freitas; da Costa, Juliana de Carvalho; Aragão, Danielle Maria de Oliveira; Castañon, Maria Christina Marques Nogueira
2014-01-01
Cecropia pachystachya is a species traditionally used in Brazil to treat inflammation. This work aims to evaluate the topical anti-inflammatory and antioxidant activities of the methanolic extract of C. pachystachya (CPM) and to perform its chemical fingerprint by HPLC-DAD. The topical anti-inflammatory activity was evaluated using the mouse models of acute ear inflammation induced by croton oil, arachidonic acid, capsaicin, EPP, phenol, and chronic inflammation induced by multiple application of croton oil. The in vitro antioxidant effect of CPM was investigated using DPPH, reducing power, β-carotene bleaching, and TBARS assays. HPLC analysis was performed to quantify the antioxidant phenolics orientin, isoorientin, and chlorogenic acid previously identified in CPM. CPM exhibited significant anti-inflammatory effect in the acute models, in some cases comparable to the reference drugs. Histopathological analysis showed a moderate chronic skin anti-inflammatory effect with decrease in vasodilation, edema, cell infiltration, and epidermal hyperproliferation. It also showed strong in vitro antioxidant activity. The contents of orientin, isoorientin, and chlorogenic acid were 66.5 ± 1.8, 118.8 ± 0.7, and 5.4 ± 0.2 µg/mg extract, respectively. The topical anti-inflammatory activity of CPM could be based on its antioxidant properties, although other effects are probably involved, including COX inhibition and other mechanisms. PMID:24877079
Comstock, Bryan
2017-01-01
Background Involving patients as partners in research is a defining characteristic of patient-centered outcomes research (PCOR). While patients’ experiential knowledge of a health condition or treatment may yield research priorities not reflected by researchers and policy makers, the methods for identifying and effectively collaborating with patients are still evolving. Patient registries and crowdsourcing may offer ease of access and convenience to both researchers and patients. Surveys and focus groups, including online modalities, have been described for prioritizing research topics. However, little is known about how these different methods compare in producing consistent priorities and similar perceptions of engagement quality among participants. Objective The aims of this study are (1) to compare how different engagement methods used to elicit patient priorities for research perform as measured by rankings for priorities generated and participant satisfaction; and (2) to determine characteristics of individuals choosing to participate in research prioritization activities. Methods Participants in the Back pain Outcomes using Longitudinal Data (BOLD) patient registry, established to evaluate the natural history of back pain among individuals 65 years and older, and participants on the Amazon Mechanical Turk (MTurk) crowdsourcing platform, to provide input on priorities for research via a questionnaire, are invited. For BOLD participants, we subsequently randomize interested respondents to 1 of 3 interactive prioritization activities to further develop priorities: a Delphi panel, an online crowd voting activity, or an in-person facilitated prioritization activity using nominal group technique (NGT). Participants involved in each activity complete a survey to evaluate the quality of the experience and a subset of these participants discuss their experience further in an interview. Descriptive statistics are used to characterize the rankings produced by each method and compare the top 5 rated topics resulting from each prioritization activity. We use rank-ordered logistic regression models to identify associations of the ranked priority topics with baseline patient characteristics. We analyze responses to the evaluation using a mixed-methods approach wherein we tabulate responses to Likert-scale questions and use content analysis to enumerate themes emerging from interviews for the 3 activities. Results In Phase I, we invite approximately 3000 BOLD participants and 500 Amazon MTurk workers to complete a research topic prioritization survey. Based on these results, we include additional topics into a subsequent prioritization survey. In Phase II, we invite BOLD participants to join 1 of 3 activities: 90 participants for Delphi panel, 100 participants for crowd voting, and 60 participants for focus groups. Of the Phase II participants, 30 will be interviewed to evaluate the activities. Conclusions This study informs decisions about how to conduct outreach to patient registry participants for providing input on research priorities, how individuals 65 years and older wish to participate in engagement activities, and how different research prioritization methods compare in terms of rankings generated and participant satisfaction. PMID:28882810
NASA Astrophysics Data System (ADS)
Prather, Edward
2018-01-01
Astronomy education researchers in the Department of Astronomy at the University of Arizona have been investigating a new framework for getting students to engage in discussions about fundamental astronomy topics. This framework is intended to also provide students with explicit feedback on the correctness and coherency of their mental models on these topics. This framework builds upon our prior efforts to create productive Pedagogical Discipline Representations (PDR). Students are asked to work collaboratively to generate their own representations (drawings, graphs, data tables, etc.) that reflect important characteristics of astrophysical scenarios presented in class. We have found these representation tasks offer tremendous insight into the broad range of ideas and knowledge students possess after instruction that includes both traditional lecture and actively learning strategies. In particular, we find that some of our students are able to correctly answer challenging multiple-choice questions on topics, however, they struggle to accurately create representations of these same topics themselves. Our work illustrates that some of our students are not developing a robust level of discipline fluency with many core ideas in astronomy, even after engaging with active learning strategies.
ERIC Educational Resources Information Center
Florida State Dept. of Education, Tallahassee. Div. of Vocational, Adult, and Community Education.
This document contains 19 lesson plans that can be used for career awareness activities in third grade. The lessons were developed by teachers and submitted as part of the Florida Blueprint for Career Preparation. The lesson plans include a topic, materials and information needed, and directions for activities. Lesson plans are designated by…
Working with the Cold War: Types of Knowledge in Swedish and Australian History Textbook Activities
ERIC Educational Resources Information Center
Ammert, Niklas; Sharp, Heather
2016-01-01
This article presents a comparative analysis of pupils' activities dealing with the Cold War in Swedish and Australian history textbooks. By focusing on textbook activities to which pupils respond in relation to their learning of a particular topic, this study identifies knowledge types included in a selection of history textbooks. The study also…
ERIC Educational Resources Information Center
Florida State Dept. of Education, Tallahassee. Div. of Vocational, Adult, and Community Education.
This document contains 17 lesson plans that can be used for career awareness activities in fifth grade. The lessons were developed by teachers and submitted as part of the Florida Blueprint for Career Preparation. The lesson plans include a topic, materials and information needed, and directions for activities. Lesson plans are designated by…
ERIC Educational Resources Information Center
Dugan, Robert E.
2002-01-01
Discusses yearly information technology costs for academic libraries. Topics include transformation and modernization activities that affect prices and budgeting; a cost model for information technologies; life cycle costs, including initial costs and recurring costs; cost benchmarks; and examples of pressures concerning cost accountability. (LRW)
Primary Science Curriculum Guide, C. Branching Out.
ERIC Educational Resources Information Center
Victoria Education Dept. (Australia).
Examples of reports from children in grades 4-6 of Education Department of Victoria schools are used to illustrate the suggestions made for teaching the topics included in the science course. Emphasis is given to methods of inter-relating science and other activities, including social studies, mathematics, writing and history. Teachers are…
Interpersonal Skills Training in a Dental Setting: A Group Interaction Approach.
ERIC Educational Resources Information Center
Eigenbrode, Charles R.
1983-01-01
General curriculum emphases on behavioral science in the first- and second-year dental curriculum culminate in a course on doctor-patient relationships, preparatory to clinic activity. The course includes discussion and essay quizzes about videotape recordings of typical doctor-patient encounters. Topics and issues included are outlined. (MSE)
Give Customers What They Meant To Ask For--Designing Training Systems at Three Levels.
ERIC Educational Resources Information Center
Hybert, Peter R.
2001-01-01
Examines instructional systems design in light of training and performance technology. Topics include the nature of design; categories of stakeholders; three levels of instructional systems design, including Curriculum Architecture Design, instructional process design, and user interface/instructional activity design; and design goals. (LRW)
Controlled Structures Technology Steering Committee Workshop
NASA Technical Reports Server (NTRS)
1992-01-01
Viewgraphs on controlled structures technology presented at the steering committee workshop on 22-23 Jan. 1992 are included. Topics addressed include: interferometer testbed; middeck 0-gravity dynamics experiment; middeck active control experiment; multivariable identification for control; strain actuated aeroelastic control; sensor/actuator technology development; input command shaping; and other research projects. A description of the organization and committee are included.
Communication about sex and HPV among Puerto Rican mothers and daughters.
Colón-López, Vivian; Fernández-Espada, Natalie; Vélez, Camille; Gonzalez, Velda J; Diaz-Toro, Elba C; Calo, William A; Savas, Lara S; Pattatucci, Angela; Fernández, María E
2017-08-01
Although opportunities to vaccinate against human papillomavirus (HPV) are available, vaccination rates in Puerto Rico remain low. Communication between parents and adolescents about sexual topics may influence decisions about HPV vaccination uptake, particularly among young women; yet, few studies have addressed this issue. This qualitative study explored Puerto Rican mothers' and daughters' communication on sex-related topics, and HPV, including the HPV vaccine. Thirty participants, including 9 mothers and 21 daughters, participated in seven focus groups. Participants were divided into groups of mothers and daughters, and further stratified by vaccination status. Transcripts were analyzed using a modified grounded theory approach to identify emergent themes. Focus group data revealed four main themes: (1) limited parent-daughter communication about sex-related topics; (2) daughters' discomfort discussing sex-related topics with their parents; (3) parental focus on abstinence; and, (4) limited parent-daughter communication about HPV and the HPV vaccine. Although daughters in this study struggled with feelings of embarrassment, invasion of privacy, encouragement of abstinence, and the fear of parents' reaction to them being sexually active prior to marriage, they also recognized the need to increase the parent-daughter communication about sex-related topics including HPV and the HPV vaccine. Educational efforts should target both daughters and parents to increase communication skills and self-efficacy and to enable them to discuss sexual health in open and nonjudgmental conversations.
Formulation, pharmacokinetics and pharmacodynamics of topical microbicides
Adams, Jessica L.; Kashuba, Angela D.M.
2013-01-01
The development of safe topical microbicides that effectively prevent human immunodeficiency virus (HIV) infection is a major goal in curbing the human immunodeficiency virus pandemic. A number of past failures resulting from mucosal toxicity or lack of efficacy have informed the field. Products that caused toxicity to the female genital tract mucosa, and thereby increased the likelihood of HIV acquisition, included nonoxynol 9, cellulose sulfate, and C31 G vaginal gel Savvy®. Topical products that were ineffective in preventing HIV infection include BufferGel®, Carraguard®, and PRO 2000®. Antiretroviral drugs such as tenofovir and dapivirine formulated into microbicide products have shown promise, but there is much to learn about ideal product formulation and acceptability, and drug distribution and disposition (pharmacokinetics). Current formulations for water-soluble molecules include vaginally or rectally applied gels, vaginal rings, films and tablets. Dosing strategies (e.g. coitally dependent or independent) will be based on the pharmacokinetics of the active ingredient and the tolerance for less than perfect adherence. PMID:22306523
Topical NSAIDs for acute pain in adults
Massey, Thomas; Derry, Sheena; Moore, R Andrew; McQuay, Henry J
2014-01-01
Background Use of topical NSAIDs to treat acute musculoskeletal conditions is widely accepted in some parts of the world, but not in others. Their main attraction is their potential to provide pain relief without associated systemic adverse events. Objectives To review the evidence from randomised, double-blind, controlled trials on the efficacy and safety of topically applied NSAIDs in acute pain. Search methods We searched MEDLINE, EMBASE, The Cochrane Library, and our own in-house database to December 2009. We sought unpublished studies by asking personal contacts and searching on-line clinical trial registers and manufacturers web sites. Selection criteria We included randomised, double-blind, active or placebo (inert carrier)-controlled trials in which treatments were administered to adult patients with acute pain resulting from strains, sprains or sports or overuse-type injuries (twisted ankle, for instance). There had to be at least 10 participants in each treatment arm, with application of treatment at least once daily. Data collection and analysis Two review authors independently assessed trial quality and validity, and extracted data. Numbers of participants achieving each outcome were used to calculate relative risk and numbers needed to treat (NNT) or harm (NNH) compared to placebo or other active treatment. Main results Forty-seven studies were included; most compared topical NSAIDs in the form of a gel, spray, or cream with a similar placebo, with 3455 participants in the overall analysis of efficacy. For all topical NSAIDs combined, compared with placebo, the number needed to treat to benefit (NNT) for clinical success, equivalent to 50% pain relief, was 4.5 (3.9 to 5.3) for treatment periods of 6 to 14 days. Topical diclofenac, ibuprofen, ketoprofen, and piroxicam were of similar efficacy, but indomethacin and benzydamine were not significantly better than placebo. Local skin reactions were generally mild and transient, and did not differ from placebo. There were very few systemic adverse events or withdrawals due to adverse events. There were insufficient data to reliably compare individual topical NSAIDs with each other or the same oral NSAID. Authors’ conclusions Topical NSAIDs can provide good levels of pain relief, without the systemic adverse events associated with oral NSAIDs, when used to treat acute musculoskeletal conditions. PMID:20556778
Science Careers and Disabled Students.
ERIC Educational Resources Information Center
Jagoda, Sue; Cremer, Bob
1981-01-01
Summarizes proceedings and student experiences at the 1980 Science Career Workshop for Physically Disabled Students at the Lawrence Hall of Science (University of California). Includes a description of the key-note speaker's topics, and other workshop activities. (DS)
ERIC Educational Resources Information Center
Herlocker, Helen; And Others
1988-01-01
Provides information on motivational activities, demonstrations, experiments, software, lessons, field trips, and a game as ideas for instructional use. Includes topics on digestion in paramecium, diffusion, cells, interactive displays, slime molds, and the construction of an underwater viewing device. (RT)
ERIC Educational Resources Information Center
Moore, John A.
1983-01-01
Discusses why there are creationists, fundamentalists, and evolutionists. Topics addressed include: modern, primitive and creationist thought; myths; appeal of occult; experiments in naturalistic thought; early evolution of American fundamentalism; militant fundamentalism; fundamentalist activities; Islamic fundamentalism; and others. Suggestions…
Incorporating International Business Topics into Every Class.
ERIC Educational Resources Information Center
Perreault, Heidi; Burchfield, Kathy
2001-01-01
Presents activities and resources for addressing international business in the curriculum, including e-mail partnerships, international document specifications, currency comparisons, marketing to other cultures, scavenger hunt, business lunch, and international telephone and travel etiquette. (SK)
Teaching Small Business Ownership and Management
ERIC Educational Resources Information Center
Leach, James A.
1977-01-01
Topics discussed include integrating small business ownership with existing programs; establishing awareness, exploration, and orientation activities; and preparation for small business ownership. A curriculum guide developed for teaching small business ownership and management is also described. (TA)
Apollo Soyuz Mission: 5-Day Report
NASA Technical Reports Server (NTRS)
1975-01-01
The Apollo Soyuz Test Project mission objectives and technical investigations are summarized. Topics discussed include: spacecraft and crew systems performance; joint flight activities; scientific and applications experiments; in-flight demonstrations; biomedical considerations; and mission support performance.
ERIC Educational Resources Information Center
School Science Review, 1984
1984-01-01
Presents 26 activities, experiments, demonstrations, games, and computer programs for biology, chemistry, and physics. Background information, laboratory procedures, equipment lists, and instructional strategies are given. Topics include eye measurements, nutrition, soil test tube rack, population dynamics, angular momentum, transition metals,…
ERIC Educational Resources Information Center
School Science Review, 1982
1982-01-01
Presents background information, laboratory procedures, classroom materials/activities, and experiments for chemistry. Topics include superheavy elements, polarizing power and chemistry of alkali metals, particulate carbon from combustion, tips for the chemistry laboratory, interesting/colorful experiments, behavior of bismuth (III) iodine, and…
Urban construction and safety project
NASA Technical Reports Server (NTRS)
1975-01-01
The purpose and functions of NASA technology applications temas (TAT) are described, with emphasis on the activities of the Urban and Construction and Safety Project. The transfer and implementation of technology is discussed in five activities. Topics include: flat conductor cable, NASA house and compendium, flood insurance studies, tornado studies, and the controller for stationary diesels.
Watch Out! A Teacher's Guide to Traffic Safety.
ERIC Educational Resources Information Center
New York City Board of Education, Brooklyn, NY. Div. of Curriculum and Instruction.
This guide provides teachers with activities that can initiate an awareness of the New York city-wide traffic safety campaign and reinforce safety education. It contains the following: (1) background information on safety rules for teachers; (2) curriculum topics that can include traffic safety issues; (3) class- and school-wide activities for…
Fundamental Studies Connected with Electrochemical Energy Storage
NASA Technical Reports Server (NTRS)
Buck, E.; Sen, R.
1974-01-01
Papers are presented which deal with electrochemical research activities. Emphasis is placed on electrochemical energy storage devices. Topics discussed include: adsorption of dendrite inhibitors on zinc; proton discharge process; electron and protron transfer; quantum mechanical formulation of electron transfer rates; and theory of electrochemical kinetics in terms of two models of activation; thermal and electrostatic.
Human Research Program Science Management: Overview of Research and Development Activities
NASA Technical Reports Server (NTRS)
Charles, John B.
2007-01-01
An overview of research and development activities of NASA's Human Research Science Management Program is presented. The topics include: 1) Human Research Program Goals; 2) Elements and Projects within HRP; 3) Development and Maintenance of Priorities; 4) Acquisition and Evaluation of Research and Technology Proposals; and 5) Annual Reviews
The American Indian Social Studies Curriculum Activity Guide, Grades 9-12.
ERIC Educational Resources Information Center
Stutzman, Esther
Designed to provide supplementary information on American Indians for the teaching of American history, the activity guide for grades 9-12 offers background knowledge and suggested discussion topics for students. Contents of the guide include: a historical timeline outlining major events from 15,000 B.C. to the present; Hollywood's influence on…
Bibliography on Multicultural Activities in the Classroom: A Listing of Resources.
ERIC Educational Resources Information Center
Brady, Mary Lou; Geile, Carole
This bibliography contains information on multicultural activities in the classroom. It is divided into three sections: a list of 97 book resources, a list of 59 journal articles, and a list of 17 ERIC (Educational Resources Information Center) resources. The resources include general multicultural teaching guides and specific topical resources:…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-13
.... The Supplement also includes questions on general health and physical exercise. Information collected in the Supplement will be published as a public use data set to facilitate research on numerous topics, such as the association between eating patterns, physical activity, and Body Mass Index; time-use...
ERIC Educational Resources Information Center
Pellicer-Chenoll, Maite; Garcia-Massó, Xavier; Morales, Jose; Serra-Añó, Pilar; Solana-Tramunt, Mònica; González, Luis-Millán; Toca-Herrera, José-Luis
2015-01-01
The relationship among physical activity, physical fitness and academic achievement in adolescents has been widely studied; however, controversy concerning this topic persists. The methods used thus far to analyse the relationship between these variables have included mostly traditional lineal analysis according to the available literature. The…
Identity Orientations: Definition, Assessment, and Personal Correlates. A Teaching Module.
ERIC Educational Resources Information Center
Carducci, Bernardo J.
Probably no other concept comes closer to encompassing the core of personality psychology than the concept of the self. This teaching activity provides instructors with a self-contained teaching module--including lecture material, an in-class activity, suggestions for in-class discussion, and supporting references--on the topic of identity…
Biology 306: Measurement and Instrumentation.
ERIC Educational Resources Information Center
Schmalhofer, Ed; And Others
A nine-week prerequisite course for biology students is presented in this monograph. A course outline is presented to provide the student with some idea of the topics and activities that he will encounter. A suggested pretest is included in the monograph which covers 32 objectives. Three Learning Activity Packages are presented. Package A -…
Our Economy: How It Works. Activities and Investigation. Teacher's Edition.
ERIC Educational Resources Information Center
Clawson, Elmer U.
To help junior and senior high school students develop a better understanding of the United States' economy, this teacher's guide presents a series of learning activities centered around eight general themes. The topics (corresponding to the document's eight chapters) include both international and global economic issues as well as current…
Korting, Hans Christian; Kiencke, Peter; Nelles, Sandra; Rychlik, Reinhard
2007-01-01
Terbinafine has been widely used with major success as a topical antifungal therapy for tinea pedis (athlete's foot). Its efficacy and safety have been validated in several clinical trials, which have demonstrated clinical efficacy for the drug after only 1 week of treatment when applied once daily, a reflection of the high fungicidal potency of the drug and its ability to form a depot in the upper skin layer. To improve patients' compliance further, a terbinafine-containing film-forming solution has been developed for single-dose therapy of athlete's foot. This novel formulation delivers terbinafine in high amounts and for a prolonged period of time into the skin, making one-shot treatment feasible. Over the past years there have been a variety of trials evaluating use of topical terbinafine addressing different pharmaceutical formulations, treatment durations, and application frequencies, but a detailed meta-analysis of these trials has not been conducted to date. The present study is the first meta-analytic evaluation of the available data on the efficacy (clinical and mycologic cure rates) and safety (adverse events) of all topical forms of terbinafine for the treatment of tinea pedis. An international, systematic literature search of 12 electronic databases (including MEDLINE, EMBASE, and Cochrane databases) using a pre-specified search strategy was conducted in March 2006. This meta-analysis included only randomized controlled trials in which terbinafine had been used for topical treatment of tinea pedis in comparison with placebo or an active control. Studies of all available topical formulations of terbinafine, frequencies of application, and durations of treatment were included. Of 100 identified articles published between 1990 and 2006, 19 met the criteria for analysis. These 19 studies involved 2899 patients with clinical and mycologic diagnoses of tinea pedis (nine placebo-controlled trials and ten active-controlled trials). Efficacy analysis demonstrated that the mycologic cure rate was significantly superior with terbinafine compared with placebo (relative risk [RR] 3.17; p < 0.001). No significant differences in efficacy were found amongst different formulations of terbinafine, treatment durations, or frequencies of application. Comparable results were obtained with respect to clinical cure rate for terbinafine compared with placebo (RR 2.75; p < 0.001). Comparison of the efficacy of terbinafine versus active control indicated a nonsignificant difference in favor of terbinafine with regard to mycologic cure rate (RR 1.03; p = 0.423) and clinical cure rate (RR 1.09; p = 0.11). The median duration of treatment was also shorter with terbinafine (1 week) compared with active controls (2 weeks). Analysis of the placebo-controlled studies showed that there was no significant difference in the risk of adverse events with terbinafine compared with placebo (RR 1.34; p = 0.34). Likewise, no significant differences in adverse events were found between terbinafine and active controls (RR 1.08; p = 0.72). Terbinafine is very well tolerated in any topical pharmaceutical formulation and also has high efficacy as a cure for tinea pedis, irrespective of type of pharmaceutical formulation, treatment duration, and frequency of application, including the recently established one-shot regimen. In addition, terbinafine has an apparently unique advantage over other antifungal agents with respect to the required duration of treatment for tinea pedis.
Ooi, N; Eady, E A; Cove, J H; O'Neill, A J
2015-02-01
To investigate the antistaphylococcal/antibiofilm activity and mode of action (MOA) of a panel of redox-active (RA) compounds with a history of human use and to provide a preliminary preclinical assessment of their potential for topical treatment of staphylococcal infections, including those involving a biofilm component. Antistaphylococcal activity was evaluated by broth microdilution and by time-kill studies with growing and slow- or non-growing cells. The antibiofilm activity of RA compounds, alone and in combination with established antibacterial agents, was assessed using the Calgary Biofilm Device. Established assays were used to examine the membrane-perturbing effects of RA compounds, to measure penetration into biofilms and physical disruption of biofilms and to assess resistance potential. A living skin equivalent model was used to assess the effects of RA compounds on human skin. All 15 RA compounds tested displayed antistaphylococcal activity against planktonic cultures (MIC 0.25-128 mg/L) and 7 eradicated staphylococcal biofilms (minimum biofilm eradication concentration 4-256 mg/L). The MOA of all compounds involved perturbation of the bacterial membrane, whilst selected compounds with antibiofilm activity caused destructuring of the biofilm matrix. The two most promising agents [celastrol and nordihydroguaiaretic acid (NDGA)] in respect of antibacterial potency and selective toxicity against bacterial membranes acted synergistically with gentamicin against biofilms, did not damage artificial skin following topical application and exhibited low resistance potential. In contrast to established antibacterial drugs, some RA compounds are capable of eradicating staphylococcal biofilms. Of these, celastrol and NDGA represent particularly attractive candidates for development as topical antistaphylococcal biofilm treatments. © The Author 2014. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.
Kahtan, S; Inman, C; Haines, A; Holland, P
1994-09-01
A survey of UK medical schools was undertaken to determine the teaching that was being offered on disability and rehabilitation. In general, teaching on this topic appeared fragmented and inadequate but a number of interesting innovations were identified. These included: a drama workshop run by a group whose members mainly have learning disabilities at St George's Medical School, student-directed learning at the University of Dundee and structured teaching programmes at the Universities of Leeds and Edinburgh. The General Medical Council Education Committee's 1991 discussion document on the undergraduate curriculum specifically mentions disability as an important topic. A number of schools mentioned that they were in the process of revising their curriculum as a consequence. Recommendations arising from the findings of the survey include integration of disability and rehabilitation into clinical teaching, focus of teaching on those types of disability which are common in the community, greater emphasis on functional assessment in teaching the physical examination, and the wider use of standard assessment instruments, for example for activities of daily living, cognitive impairment and locomotor disability. There is a need for improved communication between medical schools to facilitate the spread of educational activities on this topic.
Hungarian space research 1981-1985: Lectures and review articles
NASA Technical Reports Server (NTRS)
Benko, G. (Editor)
1986-01-01
This monograph presents an overview of Hungarian space research from 1981 to 1985. Topics discussed in the original report include the development of space research centers, the flight of the first Hungarian astronaut, Hungarian participation in international space programs such as the Vega/Halley's Comet mission and the BEALUCA materials science experiment, advances in astronomical research, and activities of the Cosmic Geodetic Observatory. Other topics discussed incude space biomedical studies, meteorological applications of space research, satellite communications, and satellite power supply systems.
Syn, Sue Yeon; Kim, Sung Un
2016-07-01
College students tend to lack access to health information. Because social networking sites (SNSs) are popularly adopted by college students, SNSs are considered to be good media channels for college students to obtain health-related information. This study examines the factors that influence college students' health information-seeking and -sharing activities on Facebook. An online survey was distributed to college students between the ages of 18 and 29 to determine intentions pertaining to health information activities according to the factors identified for the study. The factors included both contextual factors (such as health topic sensitivity and health information sources) as well as user factors (such as demographics). Our findings showed that college students are willing to read and post health-related information on Facebook when the health topic is not sensitive. In addition, there are clear differences in preferences between professional sources and personal sources as health information sources. It was found that most user factors, except gender, have no influence on health information activities. The impacts of SNS contexts, awareness of information sources, types of interlocutors, and privacy concerns are further discussed.
NASA Astrophysics Data System (ADS)
Stavrova, Olga; Urhahne, Detlef
2010-11-01
The study examines the nature, conditions, and outcomes of student learning from an organised guided tour in the Deutsches Museum in Munich. The instructional methods that best support students' cognitive and affective learning as well as how students' motivational and emotional states influence their achievement were investigated. A sample of 96 secondary school students took part in two different versions of a guided tour on an energy topic. The tours varied in the degree of support of students' active involvement, group work, and the variety of general activities offered during the tour. The data collected indicate that both tour versions led to an increase in student understanding of the visit topic to nearly the same extent. However, the version stimulating students' active participation, group work, and including a larger variety of activities aroused more positive attitudes. Students of the modified school programme showed higher interest and intrinsic motivation, felt more competent, and were less bored after the guided tour. In addition, the results suggest that students' visit-related emotional states predict the degree of their post-visit topic understanding, even when demographics and prior knowledge are taken into consideration.
Transdermal patches: history, development and pharmacology.
Pastore, Michael N; Kalia, Yogeshvar N; Horstmann, Michael; Roberts, Michael S
2015-05-01
Transdermal patches are now widely used as cosmetic, topical and transdermal delivery systems. These patches represent a key outcome from the growth in skin science, technology and expertise developed through trial and error, clinical observation and evidence-based studies that date back to the first existing human records. This review begins with the earliest topical therapies and traces topical delivery to the present-day transdermal patches, describing along the way the initial trials, devices and drug delivery systems that underpin current transdermal patches and their actives. This is followed by consideration of the evolution in the various patch designs and their limitations as well as requirements for actives to be used for transdermal delivery. The properties of and issues associated with the use of currently marketed products, such as variability, safety and regulatory aspects, are then described. The review concludes by examining future prospects for transdermal patches and drug delivery systems, such as the combination of active delivery systems with patches, minimally invasive microneedle patches and cutaneous solutions, including metered-dose systems. © 2015 The British Pharmacological Society.
Thermal Technology Development Activities at the Goddard Space Flight Center - 2001
NASA Technical Reports Server (NTRS)
Butler, Dan
2002-01-01
This presentation provides an overview of thermal technology development activities carried out at NASA's Goddard Space Flight Center during 2001. Specific topics covered include: two-phase systems (heat pipes, capillary pumped loops, vapor compression systems and phase change materials), variable emittance systems, advanced coatings, high conductivity materials and electrohydrodynamic (EHD) thermal coatings. The application of these activities to specific space missions is also discussed.
Designing Online Education Courses.
ERIC Educational Resources Information Center
Trentin, Guglielmo
2001-01-01
Focuses on the main elements that characterize online course design. Topics include design constraints; analysis of learning needs; defining objectives; course prerequisites; content structuring; course flexibility; learning strategies; evaluation criteria; course activities; course structure; communication architecture; and design evaluation.…
'GRC1.5': Uptower Gearbox Testing to Investigate Bearing Axial Cracking
DOE Office of Scientific and Technical Information (OSTI.GOV)
Keller, Jonathan; Vaes, David; McNiff, Brian
2016-02-16
This presentation focuses on the investigation of bearing axial cracking using the GRC1.5 uptower gearbox. Topics covered include the testing options considered, the project goal, and current and near-term activities.
Some Ideas on Teaching Astronomy.
ERIC Educational Resources Information Center
Allan, Phil
1980-01-01
Described are several homework activities for use in teaching Astronomy. Topics include optical telescopes, the sun, and facts about the solar system. The format is a series of true-false questions related to diagrams which students must complete. (DS)
Collected software engineering papers, volume 2
NASA Technical Reports Server (NTRS)
1983-01-01
Topics addressed include: summaries of the software engineering laboratory (SEL) organization, operation, and research activities; results of specific research projects in the areas of resource models and software measures; and strategies for data collection for software engineering research.
Educational Challenges in Toxicology.
ERIC Educational Resources Information Center
Dixon, Robert L.
1984-01-01
Issues and topics related to educational challenges in toxicology at all levels are discussed. They include public awareness and understanding, general approach to toxicology, quality structure-activity relationships, epidemiological studies, quantification of risk, and the types of toxicants studied. (JN)
Hot Topics! Heat Pumps and Geothermal Energy
ERIC Educational Resources Information Center
Roman, Harry T.
2009-01-01
The recent rapid rises in the cost of energy has significantly increased interest in alternative energy sources. The author discusses the underlying principles of heat pumps and geothermal energy. Related activities for technology education students are included.
New Year's Reading Resolutions.
ERIC Educational Resources Information Center
Bates, Nancy; And Others
1988-01-01
Activities to enhance reading with listening, thinking, writing, and fun are suggested. Topics include celebrate Reading Week, superbowl reading, book buddies, biography binge, laughing and learning, oral reading, reading sweepstakes, idea lists, fairy tale showdown, and parent reading tips. (MT)
This webinar includes the following topics: (1) Introduction and field activities, John Mitchell, (2) STAR (Science To Achieve Results) grants, Terry Keating, (3) LCA (life cycle assessment) report, (4) Mutagenicity study, David DeMarini, (5) Health effects study, Jan Dye, (6) IS...
Activities of the Solid State Physics Research Institute
NASA Technical Reports Server (NTRS)
1985-01-01
Topics addressed include: muon spin rotation; annealing problems in gallium arsenides; Hall effect in semiconductors; computerized simulation of radiation damage; single-nucleon removal from Mg-24; and He-3 reaction at 200 and 400 MeV.
ERIC Educational Resources Information Center
Murray, A. J. S.; And Others
1988-01-01
Presents 31 science activities for use with high school or college science classes. Topics included are: chromatography, ecology, invertebrates, enzymes, genetics, botany, creep, crystals, diffusion, computer interfaces, acid rain, teaching techniques, chemical reactions, waves, electric fields, rainbows, electricity, magnetic fields, and a Pitot…
NASA Astrophysics Data System (ADS)
Holmes, C. P.; Kinter, J. L.; Beebe, R. F.; Feigelson, E.; Hurlburt, N. E.; Mentzel, C.; Smith, G.; Tino, C.; Walker, R. J.
2017-12-01
Two years ago NASA established the Ad Hoc Big Data Task Force (BDTF - https://science.nasa.gov/science-committee/subcommittees/big-data-task-force), an advisory working group with the NASA Advisory Council system. The scope of the Task Force included all NASA Big Data programs, projects, missions, and activities. The Task Force focused on such topics as exploring the existing and planned evolution of NASA's science data cyber-infrastructure that supports broad access to data repositories for NASA Science Mission Directorate missions; best practices within NASA, other Federal agencies, private industry and research institutions; and Federal initiatives related to big data and data access. The BDTF has completed its two-year term and produced several recommendations plus four white papers for NASA's Science Mission Directorate. This presentation will discuss the activities and results of the TF including summaries of key points from its focused study topics. The paper serves as an introduction to the papers following in this ESSI session.
Topical Resiquimod Protects against Visceral Infection with Leishmania infantum chagasi in Mice
Craft, Noah; Birnbaum, Ron; Quanquin, Natalie; Erfe, Marie Crisel B.; Quant, Cara; Haskell, Jacquelyn
2014-01-01
New prevention and treatment strategies are needed for visceral leishmaniasis, particularly ones that can be deployed simply and inexpensively in areas where leishmaniasis is endemic. Synthetic molecules that activate Toll-like receptor 7 and 8 (TLR7/8) pathways have previously been demonstrated to enhance protection against cutaneous leishmaniasis. We initially sought to determine whether the TLR7/8-activating molecule resiquimod might serve as an effective vaccine adjuvant targeting visceral leishmaniasis caused by infection with Leishmania infantum chagasi. Resiquimod was topically applied to the skin of mice either prior to or after systemic infection with L. infantum chagasi, and parasite burdens were assessed. Surprisingly, topical resiquimod application alone, in the absence of vaccination, conferred robust resistance to mice against future intravenous challenge with virulent L. infantum chagasi. This protection against L. infantum chagasi infection persisted as long as 8 weeks after the final topical resiquimod treatment. In addition, in mice with existing infections, therapeutic treatment with topical resiquimod led to significantly lower visceral parasite loads. Resiquimod increased trafficking of leukocytes, including B cells, CD4+ and CD8+ T cells, dendritic cells, macrophages, and granulocytes, in livers and spleens, which are the key target organs of visceralizing infection. We conclude that topical resiquimod leads to systemic immune modulation and confers durable protection against visceralizing L. infantum chagasi infection, in both prophylactic and therapeutic settings. These studies support continued studies of TLR-modulating agents to determine mechanisms of protection and also provide a rationale for translational development of a critically needed, novel class of topical, preventative, and therapeutic agents for these lethal infections. PMID:25030052
Keppel Hesselink, Jan M; Kopsky, David J; Stahl, Stephen M
2017-01-01
Topical analgesics can be defined as topical formulations containing analgesics or co-analgesics. Since 2000, interest in such formulations has been on the rise. There are, however, four critical issues in the research and development phases of topical analgesics: 1) The selection of the active pharmaceutical ingredient. Analgesics and co-analgesics differ greatly in their mechanism of action, and it is required to find the most optimal fit between such mechanisms of action and the pathogenesis of the targeted (neuropathic) pain. 2) Issues concerning the optimized formulation. For relevant clinical efficacy, specific characteristics for the selected vehicle (eg, cream base or gel base) are required, depending on the physicochemical characteristics of the active pharmaceutical ingredient(s) to be delivered. 3) Well-designed phase II dose-finding studies are required, and, unfortunately, such trials are missing. In fact, we will demonstrate that underdosing is one of the major hurdles to detect meaningful and statistically relevant clinical effects of topical analgesics. 4) Selection of clinical end points and innovatively designed phase III trials. End point selection can make or break a trial. For instance, to include numbness together with tingling as a composite end point for neuropathic pain seems stretching the therapeutic impact of an analgesic too far. Given the fast onset of action of topical analgesics (usually within 30 minutes), enrichment designs might enhance the chances for success, as the placebo response might decrease. Topical analgesics may become promising inroads for the treatment of neuropathic pain, once sufficient attention is given to these four key aspects.
NASA Astrophysics Data System (ADS)
Beddow, B.; Roberts, C.; Rankin, J.; Bloch, A.; Peizer, J.
1981-01-01
The National Accident Sampling System (NASS) is described. The study area discussed is one of the original ten sites selected for NASS implementation. In addition to collecting data from the field, the original ten sites address questions of feasibility of the plan, projected results of the data collection effort, and specific operational topics, e.g., team size, sampling requirements, training approaches, quality control procedures, and field techniques. Activities and results of the first three years of the project, for both major tasks (establishment and operation) are addressed. Topics include: study area documentation; team description, function and activities; problems and solutions; and recommendations.
Missing and accounted for: gaps and areas of wealth in the public health review literature
2011-01-01
Background High-quality review evidence is useful for informing and influencing public health policy and practice decisions. However, certain topic areas lack representation in terms of the quantity and quality of review literature available. The objectives of this paper are to identify the quantity, as well as quality, of review-level evidence available on the effectiveness of public health interventions for public health decision makers. Methods Searches conducted on http://www.health-evidence.ca produced an inventory of public health review literature in 21 topic areas. Gaps and areas of wealth in the review literature, as well as the proportion of reviews rated methodologically strong, moderate, or weak were identified. The top 10 topic areas of interest for registered users and visitors of http://www.health-evidence.ca were extracted from user profile data and Google Analytics. Results Registered users' top three interests included: 1) healthy communities, 2) chronic diseases, and 3) nutrition. The top three preferences for visitors included: 1) chronic diseases, 2) physical activity, and 3) addiction/substance use. All of the topic areas with many (301+) available reviews were of interest to registered users and/or visitors (mental health, physical activity, addiction/substance use, adolescent health, child health, nutrition, adult health, and chronic diseases). Conversely, the majority of registered users and/or visitors did not have preference for topic areas with few (≤ 150) available reviews (food safety and inspection, dental health, environmental health) with the exception of social determinants of health and healthy communities. Across registered users' and visitors' topic areas of preference, 80.2% of the reviews were of well-done methodological quality, with 43.5% of reviews having a strong quality rating and 36.7% a moderate review quality rating. Conclusions In topic areas in which many reviews are available, higher level syntheses are needed to guide policy and practice. For other topic areas with few reviews, it is necessary to determine whether primary study evidence exists, or is needed, so that reviews can be conducted in the future. Considering that less than half of the reviews available on http://www.health-evidence.ca are of strong methodological quality, the quality of the review-level evidence needs to improve across the range of public health topic areas. PMID:21967658
A Resource File for Social Studies in Utah. Level 10-12: U.S. Government.
ERIC Educational Resources Information Center
Utah State Office of Education, Salt Lake City.
This resource file contains information for Utah high school teachers to help students meet the state's instructional objectives in the elective U.S. government course. Each activity includes an instructional objective along with a title, topic, time segment, procedures, materials, evaluation, and adaptation. Sample objectives include comparing…
The View Finder: Expanding Boundaries and Perspectives in Special Education. Volume One.
ERIC Educational Resources Information Center
Michael, Robert J., Ed.; Juul, Kristen D., Ed.
1992-01-01
The articles included in this monograph represent a broad range of topics reflecting the current world scene with regard to the education of children with special needs. Titles and authors of the articles include: "UNESCO and Special Education" (Lena Saleh), which discusses the history, purposes, and activities of the United Nations…
What Is a Gas? A Find-Out Book: Demonstrations, Experiments, Ideas.
ERIC Educational Resources Information Center
Weaver, Elbert C.
Twelve desk-top experiments and demonstrations which illustrate properties of and facts about gas are presented. Each experiment includes: purpose, materials needed, instructions, and a list of facts and properties that have been observed. Several of the activities also include questions for students and items for discussion. The topics of the…
Packaging & Other Structures. Stuff That Works! A Technology Curriculum for the Elementary Grades.
ERIC Educational Resources Information Center
Benenson, Gary
This book explores all kinds of packaging materials including bags, boxes, etc. and how they are used to protect and display products. Contents are divided into six chapters: (1) "Appetizers" includes activities that can be done individually to become familiar with the topic of packaging and structures; (2) "Concepts" provides…
Dynamic wind-tunnel testing of active controls by the NASA Langley Research Center
NASA Technical Reports Server (NTRS)
Abel, I.; Doggett, R. V.; Newsom, J. R.; Sandford, M.
1984-01-01
Dynamic wind-tunnel testing of active controls by the NASA Langley Research Center is presented. Seven experimental studies that were accomplished to date are described. Six of the studies focus on active flutter suppression. The other focuses on active load alleviation. In addition to presenting basic results for these experimental studies, topics including model design and construction, control law synthesis, active control system implementation, and wind-tunnel test techniques are discussed.
Overview of MSFC's Applied Fluid Dynamics Analysis Group Activities
NASA Technical Reports Server (NTRS)
Garcia, Roberto; Griffin, Lisa; Williams, Robert
2002-01-01
This viewgraph report presents an overview of activities and accomplishments of NASA's Marshall Space Flight Center's Applied Fluid Dynamics Analysis Group. Expertise in this group focuses on high-fidelity fluids design and analysis with application to space shuttle propulsion and next generation launch technologies. Topics covered include: computational fluid dynamics research and goals, turbomachinery research and activities, nozzle research and activities, combustion devices, engine systems, MDA development and CFD process improvements.
McPherson, A C; Hamilton, J; Kingsnorth, S; Knibbe, T J; Peters, M; Swift, J A; Krog, K; Chen, L; Steinberg, A; Ball, G D C
2017-02-01
Healthcare professionals have called for direction on how best to communicate about weight-related topics with children and families. Established scoping review methodology was used to answer the question: 'How can healthcare professionals best communicate with children and their families about obesity and weight-related topics?' We searched four scientific databases, two grey literature repositories and 14 key journals (2005-2016). Inclusion criteria were (i) children up to and including 18 years of age and/or their parents; (ii) communication about healthy weight, overweight, obesity or healthy/active living; and (iii) healthcare setting. Thirty-two articles were included. Evidence-based best practices were largely absent from the literature, although the following guiding principles were identified: (i) include all stakeholders in discussions; (ii) raise the topic of weight and health early and regularly; (iii) use strengths-based language emphasizing health over weight; (iv) use collaborative goal-setting to engage children and parents and (v) augment discussions with appropriate tools and resources. Guidance on how to implement these principles and how to negotiate relevant contextual factors (e.g. age, culture and disability) is still needed. Despite agreement on a number of guiding principles, evidence-based weight-related communication best practices are lacking. Rigorous, empirical evaluations of communication approaches are urgently required, especially those that include children's perspectives. © 2016 World Obesity Federation.
Topical retinoids in acne vulgaris: update on efficacy and safety.
Thielitz, Anja; Gollnick, Harald
2008-01-01
Topical retinoids represent a mainstay of acne treatment because they expel mature comedones, reduce microcomedone formation, and exert anti-inflammatory effects. The first-generation retinoid tretinoin (all-trans retinoic acid) and the synthetic third-generation polyaromatics adapalene and tazarotene are approved for acne treatment by the US FDA, whereas topical tretinoin, isotretinoin (13-cis retinoic acid), and adapalene are accredited in Canada and Europe. Topical retinoids have a favorable safety profile distinct from the toxicity of their systemic counterparts. Local adverse effects, including erythema, dryness, itching, and stinging, occur frequently during the early treatment phase. Their impact varies with the vehicle formation, skin type, frequency and mode of application, use of moisturizers, and environmental factors such as sun exposure or temperature. The broad anti-acne activity and safety profile of topical retinoids justifies their use as first-line treatment in most types of non-inflammatory and inflammatory acne. They are also suitable as long-term medications, with no risk of inducing bacterial resistance, for maintenance of remission after cessation of initial combination therapy.
Blog Construction as an Effective Tool in Biochemistry Active Learning
ERIC Educational Resources Information Center
Cubas Rolim, Estêvão; Martins de Oliveira, Julia; Dalvi, Luana T.; Moreira, Daniel C.; Garcia Caldas, Natasha; Fernandes Lobo, Felipe; André Polli, Démerson; Campos, Élida G.; Hermes-Lima, Marcelo
2017-01-01
To boost active learning in undergraduate students, they were given the task of preparing blogs on topics of clinical biochemistry. This "experiment" lasted for 12 teaching-semesters (from 2008 to 2013), and included a survey on the blogs' usefulness at the end of each semester. The survey (applied in the 2008-2010 period) used a…
How Do I Manage? An Introduction to Management. Supplementary Material and Workbook.
ERIC Educational Resources Information Center
North West Regional Management Centre, Chorley (England).
This book contains supplementary material for a British self-study course in management designed as an introduction to the course for the Certificate in Management Studies. The materials in this book are learning activities referenced to various topics in the course materials. The nine activities include a case study of a production supervision…
Das Sprachlabor in der Schule (The Language Laboratory in Schools).
ERIC Educational Resources Information Center
Cabus, Hans-Joachim; Freudenstein, Reinhold
This technical manual for the use of language laboratories includes information on the following topics: (1) types of laboratories, (2) the tape, (3) the tape recorder, (4) other basic technical equipment, (5) the audio-active laboratory, the audio-active-compare laboratory, and an evaluation of the two, (6) possibilities for expanded use, (7)…
The World's Best Places: Classroom Explorations in Geography & Environmental Science.
ERIC Educational Resources Information Center
Graf, Mike
This book offers an alternative to traditional upper elementary and middle school lesson plans, using 32 of the world's national parks as a springboard for activities. The activities in the book are divided into chapters that deal with particular topics of study: wildlife, plant life, geography, and geology. Includes step-by-step instructions that…
ERIC Educational Resources Information Center
Virginia State Dept. of Education, Richmond.
This resource handbook, which is designed for use by instructors of courses in advanced marketing, consists of a duty/task list with referenced resources, a duty/task list with learning activities, and a list of resources. Included in each list are materials dealing with the following topics: communication in marketing, economics in marketing,…
Science Indicators and Science Priorities.
ERIC Educational Resources Information Center
Brooks, Harvey
1982-01-01
Discusses science/society interface and difficulties involved in developing realistic science indicators. Topics include: intrinsic vs. extrinsic indicators; four problems society faces as a result of technological activities (toxic chemicals, radioactive wastes, auto safety, cancer); research and development (R&D) priorities; international…
ERIC Educational Resources Information Center
Morrow, Joyce
Materials for running a student government program at the junior high school level are provided in three general sections. Section 1 is a description of student government operations. Topics covered include student government responsibilities and activities, student council meeting procedures, parliamentary rules, responsibilities of the…
EVA Physiology, Systems and Performance [EPSP] Project
NASA Technical Reports Server (NTRS)
Gernhardt, Michael L.
2010-01-01
This viewgraph presentation gives a general overview of the biomedical and technological challenges of Extravehicular Activity (EVA). The topics covered include: 1) Prebreathe Protocols; 2) Lunar Suit Testing and Development; and 3) Lunar Electric Rover and Exploration Operations Concepts.
Studying the Environment by Mail
ERIC Educational Resources Information Center
McNeil, R. J.
1971-01-01
Two correspondence courses, Conservation of Natural Resources" and Current Topics in Conservation," offered by Cornell University, New York, from 1961 through 1967, are described. Included are facts and statistical tables related to: advertising; participant characteristics, educational level, and activity interests; preparation of…
Relevant Telecomputing Activities.
ERIC Educational Resources Information Center
Ross, Patricia
1995-01-01
Discusses the use of telecomputing in classrooms. Topics include telecomputing goals; use of the Internet; language arts and music FTP (file transfer protocol) sites; social studies FTP sites; science Telnet sites; social studies Telnet sites; skill building and learning processes; and instructional design. (LRW)
ERIC Educational Resources Information Center
School Science Review, 1985
1985-01-01
Presents 23 experiments, demonstrations, activities, and computer programs in biology, chemistry, and physics. Topics include lead in petrol, production of organic chemicals, reduction of water, enthalpy, X-ray diffraction model, nuclear magnetic resonance spectroscopy, computer simulation for additive mixing of colors, Archimedes Principle, and…
Science Teaching to Fire the Imagination.
ERIC Educational Resources Information Center
Sandford, Diana; Fleetwood, Julie
1997-01-01
Presents a range of exciting ideas for encouraging active learning, for illuminating new concepts, and for making science lessons fun. Topics include modeling, matter, heat, diffusion, changes of state, heat transfer, energy changes, atomic structure, waves, gravity, enzymes, and habitats. (JRH)
TEAM Webinar Series | EGRP/DCCPS/NCI/NIH
View archived webinars from the Transforming Epidemiology through Advanced Methods (TEAM) Webinar Series, hosted by NCI's Epidemiology and Genomics Research Program. Topics include participant engagement, data coordination, mHealth tools, sample selection, and instruments for diet & physical activity assessment.
Space Operations in the Eighties.
ERIC Educational Resources Information Center
Aviation/Space, 1982
1982-01-01
Highlights activities/accomplishments and future endeavors related to space operations. Topics discussed include the Space Shuttle, recovery/refurbishment operations, payload manipulator, upper stages operations, tracking and data relay, spacelab, space power systems, space exposure facility, space construction, and space station. (JN)
Application of Physics and Chemistry to Archeology: A New Undergraduate Course
ERIC Educational Resources Information Center
Meschel, Susan V.
1976-01-01
Describes a course that covers such topics as the archeological dating processes and methods that enable the identification and authentication of artifacts, including X-ray diffraction, optical emission spectroscopy, infrared spectroscopy, and neutron activation analysis. (MLH)
Role of mitogen activated protein kinases in skin tumorigenicity of Patulin
DOE Office of Scientific and Technical Information (OSTI.GOV)
Saxena, Neha; Ansari, Kausar M.; Kumar, Rahul
2011-12-15
WHO has highlighted the need to evaluate dermal toxicity of mycotoxins including Patulin (PAT), detected in several fruits. In this study the skin carcinogenic potential of topically applied PAT was investigated. Single topical application of PAT (400 nmol) showed enhanced cell proliferation ({approx} 2 fold), along with increased generation of ROS and activation of ERK, p38 and JNK MAPKs, in mouse skin. PAT exposure also showed activation of downstream target proteins, c-fos, c-Jun and NF-{kappa}B transcription factors. Further, single topical application of PAT (400 nmol) followed by twice weekly application of TPA resulted in tumor formation after 14 weeks, indicatingmore » the tumor initiating activity of PAT. However no tumors were observed when PAT was used either as a complete carcinogen (80 nmol) or as a tumor promoter (20 nmol and 40 nmol) for 25 weeks. Histopathological findings of tumors found in PAT/TPA treated mice showed that these tumors were of squamous cell carcinoma type and similar to those found in the positive control group (DMBA/TPA) along with significant increase of lipid peroxidation and decrease in free sulfydryls, catalase, superoxide dismutase and glutathione reductase activities. The results suggest the possible role of free radicals in PAT mediated dermal tumorigenicity involving MAPKs. -- Highlights: Black-Right-Pointing-Pointer Single topical application of Patulin showed enhanced cell proliferation. Black-Right-Pointing-Pointer Patulin activate MAPKs, c-fos, c-Jun and NF-{kappa}B transcription factors. Black-Right-Pointing-Pointer Patulin showed skin tumor initiating potential. Black-Right-Pointing-Pointer We could not detect skin tumor promoting potential of Patulin at the tested dose. Black-Right-Pointing-Pointer However prolonged exposure of Patulin at a higher dose may promote tumor.« less
Lavallee, Danielle C; Comstock, Bryan; Scott, Mary R; Avins, Andrew L; Nerenz, David R; Edwards, Todd C; Patrick, Donald L; Lawrence, Sarah O; Bauer, Zoya; Truitt, Anjali R; Jarvik, Jeffrey G
2017-09-07
Involving patients as partners in research is a defining characteristic of patient-centered outcomes research (PCOR). While patients' experiential knowledge of a health condition or treatment may yield research priorities not reflected by researchers and policy makers, the methods for identifying and effectively collaborating with patients are still evolving. Patient registries and crowdsourcing may offer ease of access and convenience to both researchers and patients. Surveys and focus groups, including online modalities, have been described for prioritizing research topics. However, little is known about how these different methods compare in producing consistent priorities and similar perceptions of engagement quality among participants. The aims of this study are (1) to compare how different engagement methods used to elicit patient priorities for research perform as measured by rankings for priorities generated and participant satisfaction; and (2) to determine characteristics of individuals choosing to participate in research prioritization activities. Participants in the Back pain Outcomes using Longitudinal Data (BOLD) patient registry, established to evaluate the natural history of back pain among individuals 65 years and older, and participants on the Amazon Mechanical Turk (MTurk) crowdsourcing platform, to provide input on priorities for research via a questionnaire, are invited. For BOLD participants, we subsequently randomize interested respondents to 1 of 3 interactive prioritization activities to further develop priorities: a Delphi panel, an online crowd voting activity, or an in-person facilitated prioritization activity using nominal group technique (NGT). Participants involved in each activity complete a survey to evaluate the quality of the experience and a subset of these participants discuss their experience further in an interview. Descriptive statistics are used to characterize the rankings produced by each method and compare the top 5 rated topics resulting from each prioritization activity. We use rank-ordered logistic regression models to identify associations of the ranked priority topics with baseline patient characteristics. We analyze responses to the evaluation using a mixed-methods approach wherein we tabulate responses to Likert-scale questions and use content analysis to enumerate themes emerging from interviews for the 3 activities. In Phase I, we invite approximately 3000 BOLD participants and 500 Amazon MTurk workers to complete a research topic prioritization survey. Based on these results, we include additional topics into a subsequent prioritization survey. In Phase II, we invite BOLD participants to join 1 of 3 activities: 90 participants for Delphi panel, 100 participants for crowd voting, and 60 participants for focus groups. Of the Phase II participants, 30 will be interviewed to evaluate the activities. This study informs decisions about how to conduct outreach to patient registry participants for providing input on research priorities, how individuals 65 years and older wish to participate in engagement activities, and how different research prioritization methods compare in terms of rankings generated and participant satisfaction. ©Danielle C Lavallee, Bryan Comstock, Mary R Scott, Andrew L Avins, David R Nerenz, Todd C Edwards, Donald L Patrick, Sarah O Lawrence, Zoya Bauer, Anjali R Truitt, Jeffrey G Jarvik. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 07.09.2017.
Ocular Jellyfish Stings: Report of 2 Cases and Literature Review.
Mao, Chen; Hsu, Chien-Chin; Chen, Kuo-Tai
2016-09-01
An ocular jellyfish sting is an ophthalmic emergency and is rarely reported in the medical literature. With the evolution of aquatic activities and entertainment in recent decades, we anticipate that more patients with ocular jellyfish stings may be taken to the emergency department. However, most physicians are unaware of the typical presentations, suitable treatments, prognosis, and possible complications of ocular jellyfish stings. We reported 2 cases with ocular jellyfish stings and collected cases series from literature review. The most common clinical features of ocular jellyfish stings were pain, conjunctival injection, corneal lesion, and photophobia. All patients who sustained ocular stings did so during aquatic activities, and the best management at the scene was proper analgesics and copious irrigation of affected eyes with seawater or saline. The ocular lesions were treated with topical cycloplegics, topical steroids, topical antibiotics, topical antihistamines, and removal of nematocysts. The prognosis was good, and all patients recovered without any permanent sequelae. However, symptoms in some patients may last longer than 1 week. Reported complications included iritis, increased intraocular pressures, mydriasis, decreased accommodation, and peripheral anterior synechiae. Copyright © 2016 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.
Tong, Allison; Lopez-Vargas, Pamela; Howell, Martin; Phoon, Richard; Johnson, David; Campbell, Denise; Walker, Rowan G; Craig, Jonathan C
2012-12-01
Consumer involvement in guideline development is advocated, but minimal participation, such as a nominated consumer representative on a guideline working group, can inhibit their decision-making power and contribution. Little is known about how to involve consumers more effectively in guideline development. To describe a targeted approach for involving consumers actively in guideline development, by focusing on topic and outcome selection, and to discuss the impact on content and structure of the final guideline. Descriptive study. Patients and carers (n = 24) from a tertiary hospital in Sydney attended three structured peer-facilitated workshops to complete group-based exercises on topic and outcome selection for guidelines for early stage chronic kidney disease. These workshops were run in parallel with the guideline-writing group. For each exercise, participants formed small groups and facilitated their own discussion, recorded their responses and presented them to the wider group. The topics and outcomes identified were fed back to the guideline writers. The participants actively engaged in the workshop discussions and articulated topics and outcomes they perceived should be included in clinical guidelines. Four main changes to guideline-related outputs were observed. A new guideline subtopic was introduced, guidelines were consumer-endorsed, guideline recommendations and suggestions for clinical care were augmented with consumer-focused issues, and plain English guidelines were developed. Consumer workshops in parallel and feeding into guideline development can be a feasible and effective approach for active consumer contribution. This process can inform the development of both consumer-focused guidelines for clinicians and specific versions for consumers. © 2011 Blackwell Publishing Ltd.
Third Annual Foreign Acquisitions Workshop: Improving Access to Foreign Gray Literature
NASA Technical Reports Server (NTRS)
1993-01-01
The theme of the Third Annual Foreign Acquisitions Workshop was the acquisition of and access to foreign (non-U.S.) gray literature. Individual presentations addressed general topics related to the value and scope of gray literature, specialized and foreign gray-literature sources, intellectual property issues, and U.S. Federal Agency activities. Additional topics focused on electronic access and evaluation techniques and the current and potential uses of networking technology. The workshop papers are presented in their entirety or in abstract or outline form. Appendices include a listing of databases that include foreign gray literature, a bibliography, and a report on U.S.-Japan cooperation in the use of scientific and technical information.
Khemis, A; Duteil, L; Tillet, Y; Dereure, O; Ortonne, J-P
2014-09-01
Topical or systemic antiviral drugs reduce the duration of genital herpes recurrences but may not always alleviate functional symptoms. To assess the efficacy and safety of oxygenated glycerol triesters-based CS21 barrier genital gel(®) vs. topical aciclovir and placebo (vehicle) in resolving functional symptoms and in healing of genital herpes recurrences. A prospective randomized controlled, investigator-blinded trial of CS21 barrier genital gel(®) vs. topical aciclovir (reference treatment) and placebo (vehicle) was designed. The primary endpoint was the cumulative score of four herpes-related functional symptoms (pain, burning, itching and tingling sensations). Secondary endpoints included objective skin changes (erythema, papules, vesicles, oedema, erosion/ulceration, crusts), time to heal, local tolerance and overall acceptability of the treatment as reported by a self-administered questionnaire. Overall, 61 patients were included. CS 21 barrier genital gel(®) was significantly more efficient than topical aciclovir and vehicle for subjective symptoms and pain relief in genital herpes recurrences; additionally, time to heal was significantly shorter with CS 21 than with vehicle, whereas no significantly difference was observed between patients receiving topical aciclovir and vehicle. The treatments under investigation were well tolerated and the adverse events were comparable in the three treatment groups. Overall, these results support the interest of using of CS 21 barrier genital gel(®) in symptomatic genital herpes recurrences. Accordingly, this product offers a valuable alternative in topical management of recurrent genital herpes. © 2013 European Academy of Dermatology and Venereology.
Collaborative Human Engineering Work in Space Exploration Extravehicular Activities (EVA)
NASA Technical Reports Server (NTRS)
DeSantis, Lena; Whitmore, Mihriban
2007-01-01
A viewgraph presentation on extravehicular activities in space exploration in collaboration with other NASA centers, industries, and universities is shown. The topics include: 1) Concept of Operations for Future EVA activities; 2) Desert Research and Technology Studies (RATS); 3) Advanced EVA Walkback Test; 4) Walkback Subjective Results; 5) Integrated Suit Test 1; 6) Portable Life Support Subsystem (PLSS); 7) Flex PLSS Design Process; and 8) EVA Information System; 9)
ERIC Educational Resources Information Center
Truelove, Elizabeth; Dejoie, Joyce
The information provided in this booklet is meant to give the necessary background information so that the science of black holes can be taught confidently to elementary students. The featured activities can be used to engage and excite students about the topic of black holes in different disciplines and in a number of ways. Activities include:…
RMS active damping augmentation
NASA Technical Reports Server (NTRS)
Gilbert, Michael G.; Scott, Michael A.; Demeo, Martha E.
1992-01-01
The topics are presented in viewgraph form and include: RMS active damping augmentation; potential space station assembly benefits to CSI; LaRC/JSC bridge program; control law design process; draper RMS simulator; MIMO acceleration control laws improve damping; potential load reduction benefit; DRS modified to model distributed accelerations; accelerometer location; Space Shuttle aft cockpit simulator; simulated shuttle video displays; SES test goals and objectives; and SES modifications to support RMS active damping augmentation.
Yang, Jiwon; Shin, Chang-Yup; Chung, Jin Ho
2018-01-01
BACKGROUND/OBJECTIVES Ultraviolet radiation (UV) is a major cause of skin photoaging. Previous studies reported that ethanol extract (PET) of Prunus persica (L.) Batsch flowers (PPF, peach flowers) and its subfractions, particularly the ethylacetate (PEA) and n-butanol extracts (PBT), have potent antioxidant activity and attenuate the UV-induced matrix metalloproteinase (MMP) expression in human skin cells. In this study, we investigated the protective activity of PPF extract against UV-induced photoaging in a mouse model. MATERIALS/METHODS Hairless mice were treated with PET or a mixture of PEA and PBT either topically or orally along with UV irradiation. Histological changes and biochemical alterations of mouse skin were examined. Major phenolic compounds in PPF extract were analyzed using an ACQUITY UPLC system. RESULTS The overall effects of topical and oral treatments with PPF extract on the UV-induced skin responses exhibited similar patterns. In both experiments, the mixture of PEA and PBT significantly inhibited the UV-induced skin and epidermal thickening, while PET inhibited only the UV-induced epidermal thickening. Treatment of PET or the mixture of PEA and PBT significantly inhibited the UV-induced MMP-13 expression, but not typeⅠ collagen expression. Topical treatment of the mixture of PEA and PBT with UV irradiation significantly elevated catalase, superoxide dismutase (SOD) and glutathione-peroxidase (GPx) activities in the skin compared to those in the UV irradiated control group, while oral treatment of the mixture of PEA and PBT or PET elevated only catalase and SOD activities, but not GPx. Thirteen phytochemical compounds including 4-O-caffeoylquinic acid, cimicifugic acid E and B, quercetin-3-O-rhamnoside and kaempferol glycoside derivatives were identified in the PPF extract. CONCLUSIONS These results demonstrate that treatment with PET or the mixture of PEA and PBT, both topically or orally, attenuates UV-induced photoaging via the cooperative interactions of phenolic components having anti-oxidative and collagen-protective activities. PMID:29399294
Chen, Xiaoyi; Faviez, Carole; Schuck, Stéphane; Lillo-Le-Louët, Agnès; Texier, Nathalie; Dahamna, Badisse; Huot, Charles; Foulquié, Pierre; Pereira, Suzanne; Leroux, Vincent; Karapetiantz, Pierre; Guenegou-Arnoux, Armelle; Katsahian, Sandrine; Bousquet, Cédric; Burgun, Anita
2018-01-01
Background: The Food and Drug Administration (FDA) in the United States and the European Medicines Agency (EMA) have recognized social media as a new data source to strengthen their activities regarding drug safety. Objective: Our objective in the ADR-PRISM project was to provide text mining and visualization tools to explore a corpus of posts extracted from social media. We evaluated this approach on a corpus of 21 million posts from five patient forums, and conducted a qualitative analysis of the data available on methylphenidate in this corpus. Methods: We applied text mining methods based on named entity recognition and relation extraction in the corpus, followed by signal detection using proportional reporting ratio (PRR). We also used topic modeling based on the Correlated Topic Model to obtain the list of the matics in the corpus and classify the messages based on their topics. Results: We automatically identified 3443 posts about methylphenidate published between 2007 and 2016, among which 61 adverse drug reactions (ADR) were automatically detected. Two pharmacovigilance experts evaluated manually the quality of automatic identification, and a f-measure of 0.57 was reached. Patient's reports were mainly neuro-psychiatric effects. Applying PRR, 67% of the ADRs were signals, including most of the neuro-psychiatric symptoms but also palpitations. Topic modeling showed that the most represented topics were related to Childhood and Treatment initiation , but also Side effects . Cases of misuse were also identified in this corpus, including recreational use and abuse. Conclusion: Named entity recognition combined with signal detection and topic modeling have demonstrated their complementarity in mining social media data. An in-depth analysis focused on methylphenidate showed that this approach was able to detect potential signals and to provide better understanding of patients' behaviors regarding drugs, including misuse.
Elements of active vibration control for rotating machinery
NASA Technical Reports Server (NTRS)
Ulbrich, Heinz
1990-01-01
The success or failure of active vibration control is determined by the availability of suitable actuators, modeling of the entire system including all active elements, positioning of the actuators and sensors, and implementation of problem-adapted control concepts. All of these topics are outlined and their special problems are discussed in detail. Special attention is given to efficient modeling of systems, especially for considering the active elements. Finally, design methods for and the application of active vibration control on rotating machinery are demonstrated by several real applications.
ERIC Educational Resources Information Center
Yoder, Edgar Paul, Comp.
This document consists of abstracts of research and development activities of 29 studies completed in Pennsylvania during the period from January 1 to December 31, 1982. Included in the collection are abstracts of 21 masters theses and eight doctoral theses. Various topics pertaining to agricultural education are covered, including the…
ERIC Educational Resources Information Center
Lowan-Trudeau, Gregory
2017-01-01
This article is a response to Kassam, Avery, and Ruelle's insights as presented in this forum on rural science education. Topics considered include troubling the urban/rural divide in the context of Indigenous knowledge and expanding to include the common Canadian notion of the "remote," a designation rooted in our national colonial…
2011-01-01
impact on attitudes and interest in the environment and nature. For instance, Dresner and Gill (1994) conducted a pretest – posttest analysis among...variety of other activities, including outdoor education. Youth between 7 and 17 are eligible to attend. The Operation Purple® curriculum is designed ...continue such activities; (c) the extent to which those activities are sustained post-camp; and (d) whether those activities are a topic of
Using Geography To Integrate Science and Social Studies.
ERIC Educational Resources Information Center
Dircks, Henry
2002-01-01
Focuses on geography in secondary education, offering reasons why geography is becoming more popular in schools. Provides four activities that integrate science and social studies through geography. Includes topics such as ecological disasters, monsoons, the ozone layer, and global warming. (CMK)
ERIC Educational Resources Information Center
Levy, Sue
1992-01-01
Presents a library automation vendor's perspective on networking based on activities at Ameritech Information Systems. Topics discussed include the information explosion; information technology; user expectations and needs; remote access; the library of the future; systems integration; ownership versus access; copyright laws; and the role of the…
Quest Activities in the Natural Sciences.
ERIC Educational Resources Information Center
McLure, John W.
1991-01-01
Thirteen suggestions for student research projects are presented. Project topics include birds, fish, frogs or toads, insects, spiders, crustaceans, mammals, predators, and ecology. The teacher's role in managing student projects is discussed. A list of middle school textbook resources is provided. (KR)
Middle Atmosphere Program. Handbook for MAP. Volume 13: Ground-based Techniques
NASA Technical Reports Server (NTRS)
Vincent, R. A. (Editor)
1984-01-01
Topics of activities in the middle Atmosphere program covered include: lidar systems of aerosol studies; mesosphere temperature; upper atmosphere temperatures and winds; D region electron densities; nitrogen oxides; atmospheric composition and structure; and optical sounding of ozone.
What To Do in the School Classroom.
ERIC Educational Resources Information Center
Green, Rodney J.
1985-01-01
Explains the role of the professional conservationist as a teaching resource in school-based instructional programs. Offers suggestions for planning and delivering classroom presentations on natural resource topics. Includes a listing a references on hands-on activities in conservation education. (ML)
Postage Stamps as Pedagogical Instruments in the Italian Curriculum.
ERIC Educational Resources Information Center
Nuessel, Frank; Cicogna, Caterina
1992-01-01
Examination of several interrelated topics on postage stamps, including their multiple functions and significance as semiotic artifacts, precedes suggestions for incorporating them into the Italian language curriculum in such activities as reading, writing, speaking, listening, and cultural understanding. (CB)
ERIC Educational Resources Information Center
School Science Review, 1986
1986-01-01
Describes activities, games, experiments, demonstrations, and computer-oriented exercises in all science areas. Topics include energy flow through a marine ecosystem, using 2,4-dichlorophenoxyethanoic acid to demonstrate translocation in plants, use of the dichotomous key, use of leaf yeasts to monitor atmospheric pollution, and others. (JN)
ERIC Educational Resources Information Center
Stonehouse, H. B.
1979-01-01
Presents three activities that allow students to practice some of the techniques used by lunar researchers, and to become more familiar with lunar features through scrutiny of lunar photography. Topics include dimensions of a crater, different surface ages, and types of rilles. (Author/MA)
Getting Started in the Child Care Business.
ERIC Educational Resources Information Center
Kimery, Sharon
This pamphlet discusses questions to consider when planning a child care facility. Topics discussed include licensing, financial management, written policies on facility operation, recordkeeping, insurance, the physical nature of the facility, program planning, scheduling of daily activities, personnel selection, staff development, parent…
Forest resources of Mississippi - 1994
James F. Rosson
2001-01-01
The principal findings of the seventh forest survey of Mississippi and changes that have occurred since the previous survey are presented. Topics examined include forest area, ownership, forest-type groups, stand structure, basal area, timber volume, growth, removals, mortality, harvesting, and management activity.
Forest resources of Arkansas, 1995
James F. Rosson
2002-01-01
The principal findings of the seventh forest survey of Arkansas and changes that have occurred since the previous survey are presented. Topics examined include forest area, ownership, forest-type groups, stand structure, basal area, timber volume, growth, removals, mortality, harvesting, and management activity.
Comprehensive Epilepsy Program.
ERIC Educational Resources Information Center
Virginia Univ., Charlottesville. Comprehensive Epilepsy Program.
The paper describes the Comprehensive Epilepsy Program at the University of Virginia Medical Center and includes information on the following topics: basic questions about epilepsy; describing and recording seizure activity; first aid in seizure care; the inpatient and outpatient educational service component; admission and referral; international…
ERIC Educational Resources Information Center
Bilal, Dania; Barry, Jeff; Penniman, W. David
1999-01-01
Reviews automated-systems activities in libraries during the past year and profiles major vendors. Topics include new partnership arrangements driven by competition; library-systems revenues; Y2K issues; Windows-based interfaces; consulting; outsourcing; development trends; global system sales; and sales by type of library. (LRW)
A Prairie Pharmacy: An Introduction to Herbalism.
ERIC Educational Resources Information Center
Moore, Susan A.
2003-01-01
Presents a laboratory activity to teach medical biology to undergraduate nonmajor business students. Uses herbalism as the theme concept to integrate subjects, such as anatomy, physiology, medical theory, and terminology. Includes topics, such as herb collection, medicine preparation, and herb storage. (SOE)
Event-Driven X-Ray CCD Detectors for High Energy Astrophysics
NASA Technical Reports Server (NTRS)
Ricker, George R.
2004-01-01
A viewgraph presentation describing the Event-Driven X- Ray CCD (EDCCD) detector system for high energy astrophysics is presented. The topics include: 1) EDCCD: Description and Advantages; 2) Summary of Grant Activity Carried Out; and 3) EDCCD Test System.
ERIC Educational Resources Information Center
Ward, Robin E.; Wandersee, James
2000-01-01
Students must understand key concepts through reasoning, searching out related concepts, and making connections within multiple systems to learn science. The Roundhouse diagram was developed to be a concise, holistic, graphic representation of a science topic, process, or activity. Includes sample Roundhouse diagrams, a diagram checklist, and…
Motivating Students in Credit-Based Information Literacy Courses: Theories and Practice.
ERIC Educational Resources Information Center
Jacobson, Trudi E.; Xu, Lijuan
2002-01-01
Discusses methods for enhancing student motivation, particularly in information literacy courses in higher education. Topics include Keller's ARCS (Attention, Relevance, Confidence, Satisfaction). motivation model; course design; teaching behaviors; teacher enthusiasm; clarity in presenting materials; interaction; active engagement; cooperative…
UVA-UVB photoprotective activity of topical formulations containing Morinda citrifolia extract.
Serafini, Mairim Russo; Detoni, Cassia Britto; Menezes, Paula dos Passos; Pereira Filho, Rose Nely; Fortes, Vanessa Silveira; Vieira, Maria José Fonseca; Guterres, Sílvia Stanisçuaski; Cavalcanti de Albuquerque Junior, Ricardo Luiz; Araújo, Adriano Antunes de Souza
2014-01-01
Exposure to solar radiation, particularly its ultraviolet (UV) component, has a variety of harmful effects on human health. Some of these effects include sunburn cell formations, basal and squamous cell cancers, melanoma, cataracts, photoaging of the skin, and immune suppression. The beneficial photoprotective effects of topical formulations with the extract, Morinda citrifolia, have not been investigated. This present study aims to investigate the potential benefits of M. citrifolia topical application on the dorsal skin of mice, exposed to UVA-UVB light. Using 7 days of treatment, [before (baseline values) and 20 h after UV exposure], the thickness, skin barrier damage (TEWL), erythema, and histological alterations were evaluated. The results showed that the formulations containing the extract protected the skin against UV-induced damage.
Methods of measurement for semiconductor materials, process control, and devices
NASA Technical Reports Server (NTRS)
Bullis, W. M. (Editor)
1972-01-01
Activities directed toward the development of methods of measurement for semiconductor materials, process control, and devices are described. Topics investigated include: measurements of transistor delay time; application of the infrared response technique to the study of radiation-damaged, lithium-drifted silicon detectors; and identification of a condition that minimizes wire flexure and reduces the failure rate of wire bonds in transistors and integrated circuits under slow thermal cycling conditions. Supplementary data concerning staff, standards committee activities, technical services, and publications are included as appendixes.
Guided wave phenomena in millimeter wave integrated circuits and components
NASA Astrophysics Data System (ADS)
Itoh, Tatsuo
1993-01-01
Representative projects from Army Research Office are summarized. Following the narrative descriptions with appropriate illustrations, a complete list of articles published in scientific journals and those presented at national and international conferences is provided. Lists of personnel and advanced degrees are also included. The projects were carried out at The University of Texas at Austin and later at UCLA. Topics covered include: quasi-optical technique; active antenna; active filter; traveling wave transistor; slow wave, planar transmission line; and discontinuities.
Ionescu, M A; Baroni, A; Brambilla, L; Cannavò, S P; Cristaudo, A; Vedove, C Dalle; Frasca, M; Girolomoni, G; Gnecchi, L; Peris, K; Trifirò, C; Matta, A M; Robert, G
2011-06-01
Seborrheic dermatitis is a chronic inflammatory disease aggravated by Malassezia species. Toll-like receptors (TLR) are part of innate immune system that can be activated by yeasts. Previous studies showed that an association of Umbelliferae extract with a lipid (TLR2-Regul™) decreases the IL-8 expression in human skin in contact with M. furfur. The aim of this study was to assess the activity of a topical formulated with TLR2-Regul™ in the prevention of seborrheic dermatitis (SD) relapses. Immune-competent SD adult patients were treated for SD (topical imidazoles or steroids). Cleared patients were randomized and received a topical containing TLR2-Regul™ (A) or its vehicle (B). Erythema, scales and pruritus were assessed during two months. The study included 115 patients, mean age 43.4, sex ratio m/f 1.5. At week 4 the relapse rate was 26% (N.=15) in group A and 43% (N.=25) in group B. At W8 the relapse rate was 21% (N.=12) in group A and 40% (N.=23) (P=0.0309). In this series of 115 adults with seborrheic dermatitis, patients treated with a topical containing TLR-Regul™ showed a significantly less relapse rate compared with the excipient group (P<0.05). TLR modulation could represent a new therapeutic approach in the prevention of seborrheic dermatitis relapses.
Topical resiquimod protects against visceral infection with Leishmania infantum chagasi in mice.
Craft, Noah; Birnbaum, Ron; Quanquin, Natalie; Erfe, Marie Crisel B; Quant, Cara; Haskell, Jacquelyn; Bruhn, Kevin W
2014-09-01
New prevention and treatment strategies are needed for visceral leishmaniasis, particularly ones that can be deployed simply and inexpensively in areas where leishmaniasis is endemic. Synthetic molecules that activate Toll-like receptor 7 and 8 (TLR7/8) pathways have previously been demonstrated to enhance protection against cutaneous leishmaniasis. We initially sought to determine whether the TLR7/8-activating molecule resiquimod might serve as an effective vaccine adjuvant targeting visceral leishmaniasis caused by infection with Leishmania infantum chagasi. Resiquimod was topically applied to the skin of mice either prior to or after systemic infection with L. infantum chagasi, and parasite burdens were assessed. Surprisingly, topical resiquimod application alone, in the absence of vaccination, conferred robust resistance to mice against future intravenous challenge with virulent L. infantum chagasi. This protection against L. infantum chagasi infection persisted as long as 8 weeks after the final topical resiquimod treatment. In addition, in mice with existing infections, therapeutic treatment with topical resiquimod led to significantly lower visceral parasite loads. Resiquimod increased trafficking of leukocytes, including B cells, CD4(+) and CD8(+) T cells, dendritic cells, macrophages, and granulocytes, in livers and spleens, which are the key target organs of visceralizing infection. We conclude that topical resiquimod leads to systemic immune modulation and confers durable protection against visceralizing L. infantum chagasi infection, in both prophylactic and therapeutic settings. These studies support continued studies of TLR-modulating agents to determine mechanisms of protection and also provide a rationale for translational development of a critically needed, novel class of topical, preventative, and therapeutic agents for these lethal infections. Copyright © 2014, American Society for Microbiology. All Rights Reserved.
Chuang, Ming-yu (Anthony); Chinnaratha, Mohamed A; Hancock, David G; Woodman, Richard; Wong, Geoffrey R; Cock, Charles; Fraser, Robert JL
2015-01-01
OBJECTIVES: Current guidelines recommend topical steroids as first-line treatment for patients with eosinophilic esophagitis (EoE). However, the evidence for this approach has been inconsistent in earlier reports. This meta-analysis aimed to clarify the efficacy of topical steroid treatment in active EoE using updated evidence. METHODS: CENTRAL, MEDLINE and EMBASE databases were searched for randomized controlled trials (RCTs) published up to May 2014 that compared topical steroids with control treatments for active EoE. Study bias was assessed using the Cochrane Collaboration Tool, and outcomes were pooled using random effects models. The primary outcome was the mean change in eosinophil counts. Secondary outcomes were symptom responses and adverse events. RESULTS: In total, seven RCTs (226 patients) were included. Topical steroids were associated with a significant reduction in esophageal mucosal eosinophil counts compared with control therapy although substantial heterogeneity between studies was observed (weighted mean difference (WMD) −27.2, 95% confidence interval (CI) −45.3 to −9.1, I2=56.2%). Subgroup analysis indicated the reduction in eosinophil counts was only present in studies where a proton pump inhibitor (PPI) trial was used to exclude other diagnoses (WMD −46.3, 95% CI −61.3 to −31.4, I2=0.0%). Subdivision of studies on the use of a PPI trial also accounted for the majority of heterogeneity among RCTs. No clear trends in symptom resolution were observed. Eleven out of 127 patients who received topical steroids developed asymptomatic esophageal candidiasis. CONCLUSIONS: These data provide updated high-quality evidence that support current guidelines for first-line EoE treatment with topical steroids after an initial PPI trial to exclude non-EoE pathologies (PROSPERO ID: CRD42014008828). PMID:25809314
Council of Energy Resources Tribes 1993 summer internship report: Nez Perce Tribe
DOE Office of Scientific and Technical Information (OSTI.GOV)
Crow, J.S.
1993-08-01
This paper is designed to be a working part of a larger project which would deal with the topic of Tribal interests affected by the DOE Environmental Restoration and Waste Management program and the approaches by which those Tribal interests can be advanced. Topics discussed in this paper include: background history of the Nez Perce Tribe`s relations with the US government; a Nez Perce view of tribal interests affected by DOE activities at Hanford; and a Nez Perce framework for private/governmental/tribal interest.
The Impact of Physical Activity and Obesity on Academic Achievement among Elementary Students
ERIC Educational Resources Information Center
Byrd, Jimmy
2007-01-01
This study compared the effect of physical activity and obesity on academic achievement and was based on the premise that the health of a child has an effect on his or her ability to learn and to achieve academically. Specifically, health-related topics of inactivity and obesity were considered. The participants included 12,607 third grade…
Parabolic Dish Solar Thermal Power Annual Program Review Proceedings
NASA Technical Reports Server (NTRS)
Lucas, J. W.
1982-01-01
The results of activities of the parabolic dish technology and applications development element of DOE's Solar Thermal Energy System Program are presented. Topics include the development and testing of concentrators, receivers, and power conversion units; system design and development for engineering experiments; economic analysis and marketing assessment; and advanced development activities. A panel discussion concerning industrial support sector requirements is also documented.
Neutron Activation Analysis of Water - A Review
NASA Technical Reports Server (NTRS)
Buchanan, John D.
1971-01-01
Recent developments in this field are emphasized. After a brief review of basic principles, topics discussed include sources of neutrons, pre-irradiation physical and chemical treatment of samples, neutron capture and gamma-ray analysis, and selected applications. Applications of neutron activation analysis of water have increased rapidly within the last few years and may be expected to increase in the future.
HARNESSING THE CHEMISTRY OF CO{sub 2}
DOE Office of Scientific and Technical Information (OSTI.GOV)
Louie, Janis
2012-11-30
Our research presents several strategies for addressing the challenges of activating CO2. In addition, our cycloaddition chemistry addresses several fundamental issues pertaining to catalysis as it applies to energy conservation. Topics addressed include: DEVELOPMENT OF A CYCLOADDITION CATALYST; INCREASING THE UTILITY OF THE NI CYCLOADDITION CATALYST; UNDERSTANDING THE MECHANISM OF NI-CATALYZED CYCLOADDITION; and METAL-FREE CO{sub 2} ACTIVATION.
NASA Dryden Flight Research Center C-17 Research Overview
NASA Technical Reports Server (NTRS)
Miller, Chris
2007-01-01
A general overview of NASA Dryden Flight Research Center's C-17 Aircraft is presented. The topics include: 1) 2006 Activities PHM Instrumentation Refurbishment; 2) Acoustic and Vibration Sensors; 3) Gas Path Sensors; 4) NASA Instrumentation System Racks; 5) NASA C-17 Simulator; 6) Current Activities; 7) Future Work; 8) Lawn Dart ; 9) Weight Tub; and 10) Parachute Test Vehicle.
NASA Technical Reports Server (NTRS)
1978-01-01
General highlights of NASA's activities for 1978 are presented. The highlights are categorized into topics such as space science, space transportation systems, space and terrestrial applications, environment, technology utilization, aeronautics, space research and technology, energy programs, and international. A list of the 1978 launches including: (1) launch date; (2) payload designation; (3) launch vehicle; (4) launch site and (5) mission remarks is also presented.
Secrets of the Marsh. An Activity Resource Book For and By Children. Second Edition.
ERIC Educational Resources Information Center
Euler, Aline, Ed.
This publication contains a collection of student-produced activities about wildlife. Children's views of the varying life forms that they encountered in field walks to a marsh are expressed through the games, puzzles, stories, and pictures that they created. Samples of the students' work are organized into separate topic areas. These include: (1)…
ERIC Educational Resources Information Center
Hunken, Jorie; And Others
Forty-five activity-oriented gardening and environmental education activities suitable for grades 4-6 are presented. They include such topics as demonstrating how to plan, plant, care for and harvest herb, flower, and vegetable gardens. This book teaches a basic understanding of plant growth and development through the use of illustrations and…
Draelos, Zoe Diana; Stein Gold, Linda F; Murrell, Dedee F; Hughes, Matilda H; Zane, Lee T
2016-02-01
Two post hoc analyses assessed the antipruritic activity of crisaborole topical ointment, 2% (crisaborole; Anacor Pharmaceuticals, Inc., Palo Alto, CA), a first-in-class boron-based phosphodiesterase-4 inhibitor in development for treatment of mild to moderate atopic dermatitis (AD). Two pooled analyses included data from 4 studies evaluating crisaborole in AD (study 1, phase 1b, systemic exposure, safety, and pharmacokinetics [PK] under maximal-use conditions in children and adolescents; study 2, phase 2a, safety and PK in adolescents; study 3, phase 2a, efficacy and safety in adults; study 4, phase 2, efficacy and safety in adolescents). Pooled data from studies 1 and 2 included whole body assessments; studies 3 and 4 included target lesion assessments. Pruritus severity was evaluated using a 4-point rating scale (0=none to 3=severe). Efficacy assessments included percent change from baseline in pruritus severity scores at days 8 (first pooled assessment), 15, 22, and 29 (whole body assessments) or days 15 (first pooled assessment), 22, and 29 (target lesions). Paired t-tests comparing change from baseline against zero were used to calculate P values. Categorical shifts in pruritus severity were also assessed (no to mild pruritus, 0-1.5; moderate to severe pruritus, 2-3). In the pooled analysis of studies 1 and 2 (N=57), the percent change from baseline in pruritus severity scores were 63.0% and 64.9% at days 8 and 29, respectively (P<0.001 for each). Similar results were observed in the pooled analysis of studies 3 and 4 (N=67). In both analyses, most patients had mild to no pruritus from the first time point assessed through the remainder of treatment. Treatment with crisaborole topical ointment, 2% resulted in statistically significant reductions in pruritus severity at the first time point evaluated in both analyses. These findings provide preliminary evidence of the antipruritic activity of crisaborole topical ointment, 2%.
Parenting an overweight or obese teen; issues and advice from parents
Boutelle, Kerri N.; Feldman, Shira; Neumark-Sztainer, Dianne
2013-01-01
Objective This qualitative study addresses: 1) What challenges do parents of overweight adolescents face? 2) What advice do parents of overweight adolescents have for other parents? Design One-on-one interviews were conducted with 27 parents of overweight or previously overweight adolescents Setting Medical clinic at the University of Minnesota Participants 27 parents of adolescents (12-19 years) who were either currently or previously overweight recruited from the community Main Outcome Measures. Qualitative interviews related to parenting overweight adolescents Analysis Content analysis was used to identify themes regarding parental experiences. Results Issues most frequently mentioned: 1) uncertainty regarding effective communication with adolescent about weight-related topics, 2) inability to control adolescent’s decisions around healthy eating and activity behaviors, 3) concern for adolescent’s well-being, 4) parental feeling of responsibility/guilt. Parental advice most often provided included: 1) setting up healthy home environment, 2) parental role modeling of healthy behaviors, and 3) providing support/encouragement for positive efforts. Conclusions Topics for potential intervention development include communication and motivation of adolescents regarding weight-related topics, appropriate autonomy, and addressing negative emotions concerning the adolescent’s weight status. Targeting these topics could potentially improve acceptability and outcomes for treatments. PMID:22770833
Sánchez, Andrés R; Sheridan, Phillip J; Rogers, Roy S
2004-04-01
Bone marrow transplantation (BMT) is a common treatment used for deficiencies of host marrow or in the control of blood malignancies. Post-allogeneic BMT complications include graft-versus-host disease (GVHD). GVHD occurs when immunologically active T lymphocytes are transplanted into an immunosuppressed recipient who is genetically disparate from the donor. In this case report we describe the occurrence of oral lichen planus-like lesions as the first manifestation of chronic GVHD (c-GVHD) and the subsequent management of this disease with topical tacrolimus. Diagnostic aids included routine histology and direct immunofluorescence studies to rule out immunobullous diseases and to confirm the c-GVHD. Treatment consisted of topical application of 0.1% tacrolimus ointment three times a day. Routine histology confirmed the clinical diagnosis of oral lichen planus-like c-GVHD. Treatment with tacrolimus ointment completely resolved the oral lesions after 2 months of therapy. Topical tacrolimus at low concentrations (0.1%) shows promise in the management of oral lichen planus-like c-GVHD. Controlled studies are necessary to assess the efficacy, the duration of therapy required for effective results, and the safety of this treatment over the long-term.
Parenting an overweight or obese teen: issues and advice from parents.
Boutelle, Kerri N; Feldman, Shira; Neumark-Sztainer, Dianne
2012-01-01
This qualitative study addresses: (1) what challenges parents of overweight adolescents face and (2) what advice parents of overweight adolescents have for other parents. One-on-one interviews were conducted with parents of overweight or previously overweight adolescents. Medical clinic at the University of Minnesota. Twenty-seven parents of adolescents (12-19 years) who were either currently or previously overweight recruited from the community. Qualitative interviews related to parenting overweight adolescents. Content analysis was used to identify themes regarding parental experiences. Issues most frequently mentioned were (1) uncertainty regarding effective communication with adolescent about weight-related topics; (2) inability to control adolescents' decisions related to healthful eating and activity behaviors; (3) concern for adolescents' well-being; and (4) parental feeling of responsibility/guilt. Parental advice most often provided included: (1) setting up a healthful home environment; (2) parental role modeling of healthful behaviors; and (3) providing support/encouragement for positive efforts. Topics for potential intervention development include communication and motivation of adolescents regarding weight-related topics, appropriate autonomy, and addressing negative emotions concerning the adolescent's weight status. Targeting these topics could potentially improve acceptability and outcomes for treatments. Copyright © 2012 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.
Patient safety in the care of mentally ill people in Switzerland: Action plan 2016
Richard, Aline; Mascherek, Anna C; Schwappach, David L B
2017-01-01
Background: Patient safety in mental healthcare has not attracted great attention yet, although the burden and the prevalence of mental diseases are high. The risk of errors with potential for harm of patients, such as aggression against self and others or non-drug treatment errors is particularly high in this vulnerable group. Aim: To develop priority topics and strategies for action to foster patient safety in mental healthcare. Method: The Swiss patient safety foundation together with experts conducted round table discussions and a Delphi questionnaire to define topics along the treatment pathway, and to prioritise these topics. Finally, fields of action were developed. Results: An action plan was developed including the definition and prioritization of 9 topics where errors may occur. A global rating task revealed errors concerning diagnostics and structural errors as most important. This led to the development of 4 fields of action (awareness raising, research, implementation, and education and training) including practice-oriented potential starting points to enhance patient safety. Conclusions: The action plan highlights issues of high concern for patient safety in mental healthcare. It serves as a starting point for the development of strategies for action as well as of concrete activities.
Improving Science Communication and Engaging the Public in Astronomy and Nature
NASA Astrophysics Data System (ADS)
Arion, Douglas N.
2016-01-01
A partnershipship between Carthage College and the Appalachian Mountain Club has delivered a successful public education and outreach program that merges natural environment topics and astronomy. Over the four years of activity, over 25,000 people have received programming. The effort has trained nature educators, permanent and seasonal AMC staff, and undergraduate physics and astronomy students to integrate diverse topical material and deliver high quality programming to the lay public. Unique to the program is the holistic nature of the material delivered - an 'atypical' astronomy program. Linking observable characteristics of the natural world with astronomical history and phenomena, and emphasizing the unique sequence of events that have led to human life on Earth, the program has changed attitudes and behaviors among the public participants. Successful interventions have included hands-on observing programs (day and night) that link nature content to the observed objects; table-talk presentations on nature/astronomy topics; dark skies preservation workshops; and hands-on activities developed for younger audiences, including schools, camps, and family groups. An extensive evaluation and assessment effort managed by a leading sociologist has demonstrated the effectiveness of the approach, and contributed to continuous improvement in the program content and methods. This work was supported in part by NSF Grant 1432662.
Mental Mechanisms for Topics Identification
2014-01-01
Topics identification (TI) is the process that consists in determining the main themes present in natural language documents. The current TI modeling paradigm aims at acquiring semantic information from statistic properties of large text datasets. We investigate the mental mechanisms responsible for the identification of topics in a single document given existing knowledge. Our main hypothesis is that topics are the result of accumulated neural activation of loosely organized information stored in long-term memory (LTM). We experimentally tested our hypothesis with a computational model that simulates LTM activation. The model assumes activation decay as an unavoidable phenomenon originating from the bioelectric nature of neural systems. Since decay should negatively affect the quality of topics, the model predicts the presence of short-term memory (STM) to keep the focus of attention on a few words, with the expected outcome of restoring quality to a baseline level. Our experiments measured topics quality of over 300 documents with various decay rates and STM capacity. Our results showed that accumulated activation of loosely organized information was an effective mental computational commodity to identify topics. It was furthermore confirmed that rapid decay is detrimental to topics quality but that limited capacity STM restores quality to a baseline level, even exceeding it slightly. PMID:24744775
ERIC Educational Resources Information Center
Whitlock, Laura A.; Granger, Kara C.; Mahon, Jane D.
The information provided in this booklet is meant to give the necessary background information so that the science of black holes can be taught confidently to secondary students. The featured activities can be used to engage and excite students about the topic of black holes in different disciplines and in a number of ways. Activities include: (1)…
The integrated manual and automatic control of complex flight systems
NASA Technical Reports Server (NTRS)
Schmidt, D. K.
1986-01-01
The topics of research in this program include pilot/vehicle analysis techniques, identification of pilot dynamics, and control and display synthesis techniques for optimizing aircraft handling qualities. The project activities are discussed. The current technical activity is directed at extending and validating the active display synthesis procedure, and the pilot/vehicle analysis of the NLR rate-command flight configurations in the landing task. Two papers published by the researchers are attached as appendices.
Middle Years. For Middle Level Educators.
ERIC Educational Resources Information Center
Hechinger, Fred M.; And Others
1992-01-01
This supplement offers 10 articles focusing on middle school education. Topics include remembering adolescence, resources and teaching tips, active middle school students, adolescent development, challenges in middle school education, integrated studies, planning middle school special events, a writing-science-consumerism miniunit on popcorn,…
Solar-terrestrial Predictions Proceedings. Volume 1: Prediction Group Reports
NASA Technical Reports Server (NTRS)
Donnelly, R. F. (Editor)
1979-01-01
The current practice in solar terrestrial predictions is reviewed with emphasis of prediction, warning, and monitoring services. Topics covered include: ionosphere-reflected HF radio propagation; radiation hazards for manned space flights and high altitude and high latitude aircraft flights; and geomagnetic activity.
ERIC Educational Resources Information Center
Awkerman, Gary L.
This publication is designed for use in standard science curricula to develop oceanologic manifestations of certain science topics. Included are teacher guides, student activities, and demonstrations designed to impart ocean understanding to high school students. When the student has completed this unit, he should be able to: (1) define an…
Do-It-Yourself Air Sensors – Exploring the Atmosphere and Turning on Light Bulbs!?
These are educational slides that will be presented in a webinar to the National Science Teachers Association. Topics covered include general air quality, current EPA research, and EPA's particle sensor kit that is a classroom activity.
Chemistry with Inexpensive Materials: Spray Bottles and Plastic Bags.
ERIC Educational Resources Information Center
Zoltewicz, Susan
1993-01-01
Presents eight chemistry activities that are interesting and involve simple, easily available materials. Topics include mystery writing, valentine hearts, flame tests, evaporation race, buoyancy versus mass, determination of relative masses of gases, mole sample container, and cold and hot packs. (DDR)
Problems and Projects from Astronomy.
ERIC Educational Resources Information Center
Mills, H. R.
1991-01-01
Describes activities to stimulate school astronomy programs. Topics include: counting stars; the Earth's centripetal force; defining astronomical time; three types of sundials; perceptions of star brightness; sunspots and solar radiation; stellar spectroscopy; number-crunching and the molecular structure of the atmosphere; the Earth-Moon common…
ERIC Educational Resources Information Center
Cox, Philip L.
This material is an instructional unit on measuring and estimating. A variety of activities are used with manipulative devices, worksheets, and discussion questions included. Major topics are estimating lengths, accuracy of measurement, metric system, scale drawings, and conversion between different units. A teacher's guide is also available.…
Area. Topical Module for Use in a Mathematics Laboratory Setting.
ERIC Educational Resources Information Center
Sigurdson, Orville; And Others
This area package emphasizes three facets: (1) the concept of area as a covering; (2) the square unit; and (3) formula development. There are two enrichment activities included. The first requires the aid of a programmable calculator or computer. (Author/MK)
Volcanoes: Nature's Caldrons Challenge Geochemists.
ERIC Educational Resources Information Center
Zurer, Pamela S.
1984-01-01
Reviews various topics and research studies on the geology of volcanoes. Areas examined include volcanoes and weather, plate margins, origins of magma, magma evolution, United States Geological Survey (USGS) volcano hazards program, USGS volcano observatories, volcanic gases, potassium-argon dating activities, and volcano monitoring strategies.…
Forest resources of east Oklahoma, 1993
James F. Rosson
2001-01-01
The principal findings of the sixth forest survey of east Oklahoma (1993) and changes that have occurred since the previous survey are presented. Topics examined include forest area, ownership, forest-type groups, stand structure, basal area, timber volume, growth, removals, mortality, harvesting, and management activity.
ERIC Educational Resources Information Center
Licata, Kenneth P.
1988-01-01
Explains the use of constructing and analyzing analogies as a way to enhance student understanding and recollection of scientific concepts. Offers suggestions for topics including energy activation, phases of matter, electron transitions, equilibrium, covalent bonds, wave and particle duality, reaction types, ideal versus real gases, and oxidation…
ERIC Educational Resources Information Center
Clearing: Nature and Learning in the Pacific Northwest, 1984
1984-01-01
Presents ideas for teaching ecology in the winter. Suggested topic areas or units include snow insulation and density, snowflakes and snow crystals, goldenrod galls, bird behavior, survival techniques, bacteriology and decomposition, trees and keying, biomass and productivity, pollution, and soil organisms. A sample student activity sheet is…
ERIC Educational Resources Information Center
Kazanjian, Wendy C.
1982-01-01
Describes Project COLD (Climate, Ocean, Land, Discovery) a scientific study of the Polar Regions, a collection of 35 modules used within the framework of existing subjects: oceanography, biology, geology, meterology, geography, social science. Includes a partial list of topics and one activity (geodesic dome) from a module. (Author/SK)
Forest resources of east Texas, 1992
James F. Rosson
2000-01-01
The principal findings of the sixth forest survey of east Texas (1992) and changes that have occurred since the previous survey are presented. Topics examined include forest area, ownership, forest-type groups, stand structure, basal area, timber volume, growth, removals, mortality, harvesting, and management activity.
Digging into Minnesota Minerals.
ERIC Educational Resources Information Center
Minnesota State Dept. of Natural Resources, St. Paul.
This publication presents students with facts about geology and several learning activities. Topics covered include rocks and minerals, volcanoes and earthquakes, fossils, exploration geology, mining in Minnesota, environmental issues related to mining, mineral uses, mining history, and the geology of Minnesota's state parks. A geologic timetable…
Highlights of Aeroacoustics Research in the U.S. 1998
NASA Technical Reports Server (NTRS)
Raman, Ganesh; McLaughlin, Dennis K.
1999-01-01
Highlights of aeroacoustics research in the United States of America during 1998 are reported in a summary compiled from information provided by members of the Aeroacoustics Technical Committee of the American Institute of Aeronautics and Astronautics (AIAA) and other leading research groups in industry, national laboratories, and academia. The past few years have seen significant progress in aeroacoustics. Research has steadily progressed toward enhanced safety, noise benefits, and lower costs. Since industrial progress is generally not published in the archival literature, it is particularly important to highlight these accomplishments. This year we chose to report on five topics of great interest to the aerospace industry including a synopsis of fundamental research at universities and national laboratories. The topics chosen are: (1) Advanced Subsonic Technology (AST), (2) High Speed Research (HSR), (3) Rotorcraft, (4) Weapons bay aeroacoustics control and (5) Academic research including Computational AeroAcoustics (CAA). Although the information presented in this review is not all encompassing we hope that the topics covered will provide some insights into aeroacoustics activity in the U.S.
Tong, Allison; Tunnicliffe, David J; Lopez-Vargas, Pamela; Mallett, Andrew; Patel, Chirag; Savige, Judy; Campbell, Katrina; Patel, Manish; Tchan, Michel C; Alexander, Stephen I; Lee, Vincent; Craig, Jonathan C; Fassett, Robert; Rangan, Gopala K
2016-02-01
This study aimed to identify consumer perspectives on topics and outcomes to integrate in the Kidney Health Australia Caring for Australasians with Renal Impairment (KHA-CARI) clinical practice guidelines on autosomal-dominant polycystic kidney disease (ADPKD). A workshop involving three concurrent focus groups with 18 consumers (patients with ADPKD (n = 15), caregivers (n = 3)) was convened. Guideline topics, interventions and outcomes were identified, and integrated into guideline development. Thematic analysis was used to analyse the reasons for their choices. Twenty-two priority topics were identified, with most focussed on non-pharmacological management (diet, fluid intake, physical activity, complementary medicine), pain management and psychosocial care (mental health, counselling, cognitive and behavioural training, education, support groups). They also identified 26 outcomes including quality of life (QoL), progression of kidney disease, kidney function, cyst growth and nephrotoxity. Almost all topics and outcomes suggested were identified by health professionals with the exception of five topics/outcomes. Six themes reflected reasons for their choices: clarifying ambiguities, resolving debilitating pain, concern for family, preparedness for the future, taking control and significance of impact. Although there was considerable concordance between the priority topics and outcomes of health professionals and consumers for guidelines of ADPKD, there was also important discordance with consumers focused on fewer issues, but particularly on lifestyle, psychosocial support, pain, and QoL and renal outcomes. Active consumer engagement in guidelines development can help to ensure the inclusion of patient-centred recommendations, which may lead to better management of disease progression, symptoms, complications, and psychosocial impact. © 2015 Asian Pacific Society of Nephrology.
Tosti, Antonella; Zaiac, Martin N; Canazza, Agnese; Sanchis-Gomar, Fabian; Pareja-Galeano, Helios; Alis, Rafael; Lucia, Alejandro; Emanuele, Enzo
2016-12-01
Activation of the WNT/β-catenin pathway has emerged as a potential therapeutic target in androgenetic alopecia (AGA). Methyl vanillate (MV) - a safe plant-derived ingredient - has been recently shown to activate the WNT/β-catenin signaling. Objectives Two distinct substudies were conducted. First, we designed a 6-month, uncontrolled, open-label clinical study to investigate whether topically applied MV may increase hair count and hair mass index (HMI) in female AGA. Second, we conducted a molecular study on the effect of MV on WNT10B mRNA expression in scalp biopsies of women with AGA. A total of 20 Caucasian women (age range: 25-57 years) with AGA (Sinclair grade 1-2) were included. The research product was an alcohol-free formulation supplied in the form of a spray containing 0.2% MV as the active ingredient. In the clinical study, hair count and HMI were found to increase at 6 months by 6% (P < 0.01) and 12% (P < 0.001), respectively, compared with baseline. No participant discontinued treatment due to adverse effects, and the overall patient satisfaction was good. At the molecular level, the topical application of the research product resulted in a 32% increase in WNT10B mRNA expression levels in the temporal scalp area (P < 0.001). Our pilot data suggest that topical MV can increase hair count and HMI by inducing WNT10B expression in the scalp, potentially serving as a novel treatment strategy for female AGA. © 2016 Wiley Periodicals, Inc.
Nguyen, H T P; Munnier, E; Souce, M; Perse, X; David, S; Bonnier, F; Vial, F; Yvergnaux, F; Perrier, T; Cohen-Jonathan, S; Chourpa, I
2015-01-26
The cutaneous penetration of hydrophobic active molecules is of foremost concern in the dermatology and cosmetic formulation fields. The poor solubility in water of those molecules limits their use in hydrophilic forms such as gels, which are favored by patients with chronic skin disease. The aim of this work is to design a novel nanocarrier of hydrophobic active molecules and to determine its potential as an ingredient of a topical form. The nanocarrier consists of an oily core surrounded by a protective shell of alginate, a natural polysaccharide isolated from brown algae. These calcium alginate-based nanocarriers (CaANCs) were prepared at room temperature and without the use of organic solvent by an accelerated nanoemulsification-polymer crosslinking method. The size (hydrodynamic diameter ~200 nm) and surface charge (zeta potential ~ - 30 mV) of the CaANCs are both compatible with their application on skin. CaANCs loaded with a fluorescent label were stable in model hydrophilic galenic forms under different storage conditions. Curcumin was encapsulated in CaANCs with an efficiency of ~95%, fully retaining its antioxidant activity. The application of the curcumin-loaded CaANCs on excised human skin led to a significant accumulation of the active molecules in the upper layers of the skin, asserting the potential of these nanocarriers in active pharmaceutical and cosmetic ingredients topical delivery.
NASA Astrophysics Data System (ADS)
Nguyen, H. T. P.; Munnier, E.; Souce, M.; Perse, X.; David, S.; Bonnier, F.; Vial, F.; Yvergnaux, F.; Perrier, T.; Cohen-Jonathan, S.; Chourpa, I.
2015-06-01
The cutaneous penetration of hydrophobic active molecules is of foremost concern in the dermatology and cosmetic formulation fields. The poor solubility in water of those molecules limits their use in hydrophilic forms such as gels, which are favored by patients with chronic skin disease. The aim of this work is to design a novel nanocarrier of hydrophobic active molecules and to determine its potential as an ingredient of a topical form. The nanocarrier consists of an oily core surrounded by a protective shell of alginate, a natural polysaccharide isolated from brown algae. These calcium alginate-based nanocarriers (CaANCs) were prepared at room temperature and without the use of organic solvent by an accelerated nanoemulsification-polymer crosslinking method. The size (hydrodynamic diameter ˜200 nm) and surface charge (zeta potential ˜ - 30 mV) of the CaANCs are both compatible with their application on skin. CaANCs loaded with a fluorescent label were stable in model hydrophilic galenic forms under different storage conditions. Curcumin was encapsulated in CaANCs with an efficiency of ˜95%, fully retaining its antioxidant activity. The application of the curcumin-loaded CaANCs on excised human skin led to a significant accumulation of the active molecules in the upper layers of the skin, asserting the potential of these nanocarriers in active pharmaceutical and cosmetic ingredients topical delivery.
Ordaz-Trinidad, Nancy; Dorantes-Alvarez, Lidia; Salas-Benito, Juan
2015-01-01
Patents on phytochemicals are being registered worldwide. Such phytochemicals provide benefits to human health, and include terpenoids, phenolic compounds, alkaloids, lignin, and fiber. This review has the purpose to provide a comprehensive overview of patents published in the last five years about extraction of phytochemicals and their application in the food and pharmaceutical industry. Forty eight pa- tents were analyzed and classified in four topics of interest; 1) Extraction, 2) Functional foods, 3) Biological activity, and 4) Prevention of diseases. Extraction yield of phytochemicals is the critical step. The techniques to extract phytochemicals include enzymat- ic hydrolysis, nano-particulate precipitation, salts formation and combination of solvents; however, the use of ultrasound and microwave is increasing. Patents concerning functional foods include pediatric formulations, sport drink, and compo- sitions that produce beneficial effects. Biological activity of plant extracts tested in animals or cell cultures, as antioxidant, anti-inflammatory, anticancer activity, reduction of obesity and diabetes are presented in this review. Application of phy- tochemicals in the prevention and treatment of health disorders, such as diabetes, gastritis, enteritis, topical inflammation, macular degeneration, gingivitis, prostatic hyperplasia, urinary impairments. Patents revised include 30% methodologies for extraction of phytochemicals, 16% application of phytochem- icals in food matrixes to obtain functional foods, 18% biological activity of extracts or compounds and 36% application in the prevention and treatment of illness, which reveals a great interest to protect intellectual property concerning applica- tion of phytochemicals formulations for human health.
Fluid mechanics phenomena in microgravity; ASME Winter Annual Meeting, Anaheim, CA, Nov. 8-13, 1992
NASA Technical Reports Server (NTRS)
Siginer, Dennis A. (Editor); Weislogel, Mark M. (Editor)
1992-01-01
This paper is the first in a series of symposia presenting research activity in microgravity fluid mechanics. General topics addressed include two-phase flow and transport phenomena, thermo-capillary flow, and interfacial stability. Papers present mathmatical models of fluid dynamics in the microgravity environment. Applications suggested include space manufacturing and storage of liquids in low gravity.
Solar Physics and Terrestrial Effects: A Curriculum Guide for Teachers Grades 7-12, 2nd Edition.
ERIC Educational Resources Information Center
Briggs, Roger P.; Carlisle, Robert J.
This curriculum guide includes a brief textbook, a hands-on activity guide, and resource listings. The textbook provides background information in solar physics for teachers and contains problems suitable for advanced students at the end of each chapter. Topics covered in the textbook include stellar evolution, the structure of the sun, methods of…
Science Fare: An Illustrated Guide and Catalog of Toys, Books, and Activities for Kids.
ERIC Educational Resources Information Center
Saul, Wendy; Newman, Alan R.
This book addresses some of the methods by which science can be made accessible to children, both in school and non-school settings. It contains information on effective science education for elementary school age children, and includes a catalog of books and other materials. Topics discussed in the book include: (1) planning; (2) approaches to…
ERIC Educational Resources Information Center
Kepler, Lynne
Favorite science topics like seeds and plants, evaporation, light and shadow, and animal observation are the subjects of the eight windowsill science centers included in this book. Each of the science centers includes a discussion of the process skills that students will use, several hands-on activities, explanation of key concepts and vocabulary,…
ERIC Educational Resources Information Center
Community School District 18, Brooklyn, NY.
This is the second part of a two-part teacher's manual for an ISS-based elementary school course in the metric system. Behavioral objectives and student activities are included. Topics include: (1) capacity; (2) calculation of volume and surface area of cylinders and cones; (3) mass; (4) temperature; and (5) metric conversions. (BB)
Elementary Metric Curriculum - Project T.I.M.E. (Timely Implementation of Metric Education). Part I.
ERIC Educational Resources Information Center
Community School District 18, Brooklyn, NY.
This is a teacher's manual for an ISS-based elementary school course in the metric system. Behavioral objectives and student activities are included. The topics covered include: (1) linear measurement; (2) metric-decimal relationships; (3) metric conversions; (4) geometry; (5) scale drawings; and (6) capacity. This is the first of a two-part…
Teaching Environmental Geology in the 21St Century: A Workshop Report
NASA Astrophysics Data System (ADS)
Mogk, D. W.; Wiese, K.; Castendyk, D.; McDaris, J. R.
2012-12-01
Environmental Geology encompasses a range of topics that include geohazards, natural resources, issues such as climate change, human health, and environmental policy. Instruction in Environmental Geology provides students the opportunity to address the grand challenges facing humanity regarding how to live sustainably and responsibly on Earth. Instruction in Environmental Geology ranges from dedicated introductory courses, instructional modules in upper division Earth Science "core" classes, to courses in related disciplines such as environmental science, ecology, and the social and political sciences. To explore the opportunities of teaching Environmental Geology in all these contexts, the On the Cutting Edge program convened a workshop in June 2012 to bring together instructors representing a diversity of instructional settings. The goals of the workshop were to: 1) Share innovative teaching methods, approaches, and activities for teaching Environmental Geology and share ideas on how to teach in various contexts. 2) Examine where and how environmental geology topics are taught in the geoscience curriculum from introductory courses for non-majors to "core" geoscience courses for majors. 3) Consider the ways that Environmental Geology courses and topical materials can contribute to public science literacy, particularly how to make personal and societal decisions about the range of issues facing humanity and to live responsibly and sustainably on this planet. 4) Develop a list of best practices for integrating emerging environmental issues, recent natural disasters, and issues related to natural resources into course work and identifying how scientific data and research outcomes can inform public discourse on topical issues. 5) Develop strategies to reach under-represented groups and expand the diversity of students who enroll in our courses. 6) Identify topics of high interest and need for future development as teaching modules and courses. The workshop program included keynote talks, small group discussion sessions, interactive demonstrations, and opportunities to network and develop ideas for new instructional resources. The participants also reviewed over 300 teaching activities, and contributed to additional online resources focused on Environmental Geology. Field trips demonstrated teaching activities about environmental issues in local contexts. All workshop presentations, discussion summaries, teaching activity collections and related on-line resources are available on the workshop website. Faculty are encouraged to submit additional examples of Environmental Geology instructional resources.
Proceedings of the Conference Arctic '85; Civil Engineering in the Artic offshore
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bennett, F.L.; Machemehl, J.L.
1985-01-01
Topics of the 1985 Conference included: Arctic construction, Arctic foundation, Arctic structures, and ocean effects. Arctic terminals and coastal offshore bases, protecting the Arctic environment, and probabilistic methods in Arctic offshore engineering were also discussed. Ice mechanics, marine pipelines in the Arctic, and the role of universities in training civil engineers for Arctic offshore development were highlighted. Sessions on remote sensing, surveying, and mapping were included, and offshore installations in the Bering Sea were discussed. Another topic of discussion was research in Civil Engineering for development of the Arctic offshore. The overall thrust of the conference was the application ofmore » Arctic offshore engineering principles and research in the field of oil and gas exploration and exploitation activity.« less
The NASA Space Life Sciences Training Program - Preparing the way
NASA Technical Reports Server (NTRS)
Biro, Ronald; Munsey, Bill; Long, Irene
1990-01-01
Attention is given to the goals and methods adopted in the NASA Space Life Sciences Training Program (SLSTP) for preparing scientists and engineers for space-related life-sciences research and operations. The SLSTP is based on six weeks of projects and lectures which give an overview of payload processing and experiment flow in the space environment. The topics addressed in the course of the program include descriptions of space vehicles, support hardware, equipment, and research directions. Specific lecture topics include the gravity responses of plants, mission integration of a flight experiment, and the cardiovascular deconditioning. The SLSTP is shown to be an important part of the process of recruiting and training qualified scientists and engineers to support space activities.
Fölster-Holst, R; Abeck, D; Torrelo, A
2016-03-01
Hydrocortisone 17-butyrate 21-propionate (hydrocortisone buteprate, HBP) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. HBP is available as a 0.1% cream or ointment formulation. Good results were obtained with a once-daily topical treatment. HBP is characterized by a strong topical anti-inflammatory activity and weak systemic action. It is considered to have potency comparable to that of betamethasone 17-valerate (BV), but its systemic effects are less pronounced. HBP was shown to have a good efficacy in the treatment of various oozing and lichenified eczematous skin diseases including atopic dermatitis (AD) and in the treatment of psoriasis vulgaris. Even in very young children, HBP proved successful as an effective and safe drug. A therapeutic index of 2.0 can be attributed to this glucocorticoid. In this respect, there is no difference between topical HBP and other topical glucocorticoids with increased benefit/risk ratio, e.g. prednicarbate (PC), methylprednisolone aceponate (MPA) and mometasone furoate (MM).
Serial Killers: Academic Libraries Respond to Soaring Costs.
ERIC Educational Resources Information Center
McCarthy, Paul
1994-01-01
Discusses ways in which academic libraries are responding to rising costs of serials. Topics addressed include pricing by publishers; the effect of journal cancellations on research activities; interlibrary loans and document delivery services; coordinated cancelling; electronic journals; and experiences at the University of Arizona. (LRW)
Teaching America's Maritime Heritage
ERIC Educational Resources Information Center
Heitzman, Ray
1977-01-01
The author recommends that social studies curricula include study of American maritime heritage. He describes aspects of the heritage, such as commercial trade and water sports; suggests topics for mini-units, such as marine careers; and presents an annotated bibliography of 56 resources for teaching about maritime activities. (AV)
For Parents: An Introduction to Kindergarten.
ERIC Educational Resources Information Center
Leavitt, Midge
Prepared for parents of young children, this booklet provides information about the ways children learn in kindergarten, guidelines for judging the quality of kindergarten, and aids to understanding how kindergarten staff and classroom activities help children develop. Topics addressed include dramatic play, helping, pets, cooking, eating snacks…
Celebrate Your Freedom! May 1, Law Day 1997.
ERIC Educational Resources Information Center
Michaud, Mike; And Others
1997-01-01
Presents seven brief articles on legal issues concerning young people. Addresses such topics as curfews, teen smoking, dress codes, and child labor. Some articles are student-written while others profile student activity. Student authors include Mike Michaud, Danny Rosen, Carrie Kendrick, and William Hansen. (MJP)
Classroom Management in the Elementary Grades. Research Series No. 32.
ERIC Educational Resources Information Center
Brophy, Jere E.; Putnam, Joyce G.
The literature on elementary school classroom management is reviewed. Topics include student characteristics and individual differences, preparing the classroom as a learning environment, organizing instruction and support activities to maximize student engagement in productive tasks, developing workable housekeeping procedures and conduct rules,…
[Resources Unit, Edmonds School District.
ERIC Educational Resources Information Center
Edmonds School District 15, Lynnwood, WA.
This interdisciplinary program, developed for secondary students, contains 13 natural resource activities that can either be used directly in, or as a supplement to, curriculum in Science, Photography, Mathematics, Social Studies and English. The topics to be investigated include: raindrop impact, resource control, recycling, the world model,…
ERIC Educational Resources Information Center
Maletsky, Evan, Ed.; Yunker, Lee E., Ed.
1986-01-01
Five sets of activities for students are included in this document. Each is designed for use in junior high and secondary school mathematics instruction. The first Note concerns mathematics on postage stamps. Historical procedures and mathematicians, metric conversion, geometric ideas, and formulas are among the topics considered. Successful…
Imagery and spectroscopy of supernova remnants and H-2 regions
NASA Technical Reports Server (NTRS)
Dufour, R. J.
1984-01-01
Research activities relating to supernova remnants were summarized. The topics reviewed include: progenitor stars of supernova remnants, UV/optical/radio/X-ray imagery of selected regions in the Cygnus Loop, UV/optical spectroscopy of the Cygnus Loop spur, and extragalactic supernova remnant spectra.
A Web-Enabled Graduate Course: Two Perspectives.
ERIC Educational Resources Information Center
Penrod, James; Perry, Barbara A.
This paper describes a World Wide Web-enhanced graduate course at the University of Memphis (Tennessee) called "IT [Information Technology] Trends and Issues in Higher and Adult Education." Topics covered include the course objectives, technology used, course activities, and assignments. Four prevalent learning styles are summarized…
[Air Pollution Unit, Edmonds School District.
ERIC Educational Resources Information Center
Edmonds School District 15, Lynnwood, WA.
This interdisciplinary program, developed for secondary students, contains 16 air pollution activities that can either be used directly in, or as a supplement to, curriculum in Science, Photography, Mathematics, English, Social Studies, Industrial Arts and Home Economics. The topics to be investigated include: pollutants from automobiles, exhaust…
Say It with Pictures: Video Communicates Library Funding Needs.
ERIC Educational Resources Information Center
Hawkins, Lorraine; Huwiler, Paul
1992-01-01
Describes the effective use of a videotape to demonstrate needed funding for a children's library in the Blackstone Memorial Library (Branford, CT). Topics addressed include the production plan, planning documents, presentation treatment and storyboards, support narration, and production and editing activities. (eight references) (LRW)
The Sun & Our Skin: An Update for Biology Teachers.
ERIC Educational Resources Information Center
Anastasiou, C. J.
1991-01-01
The effect of sunlight on skin is described. Topics of discussion include the ozone layer, photosynthesis of vitamin D, tanning, the immune system, skin cancers, moles, prevention, sunscreens, effect of diet, vitamins C and E, the retinoids, carotenoids, and vaccines. Activities are provided. (KR)
ERIC Educational Resources Information Center
Bessant, Helen P., Ed.
Presented are 11 brief articles designed to help parents enhance their children's school performance and generally improve the home environment. Included is information on the following topics: the role of the social worker in parent education, home activities to improve a child's reading skills, developing listening skill through instructional…
ERIC Educational Resources Information Center
Ohrn, Deborah Gore, Ed.
1993-01-01
This quarterly publication of the State Historical Society of Iowa features articles and activities for elementary school students. This summer issue focuses on the topic of lake life. The issue includes the following features: (1) "Where the Lakes Are Map"; (2) "Letter from the Lake"; (3) "Lake People"; (4)…
NASA Technical Reports Server (NTRS)
1976-01-01
Various phases of planetary operations related to the Viking mission to Mars are described. Topics discussed include: approach phase, Mars orbit insertion, prelanding orbital activities, separation, descent and landing, surface operations, surface sampling and operations starting, orbiter science and radio science, Viking 2, Deep Space Network and data handling.
Water Quality Unit, Edmonds School District.
ERIC Educational Resources Information Center
Edmonds School District 15, Lynnwood, WA.
This interdisciplinary program, developed for secondary students, contains 20 water quality activities that can either be used directly in, or as a supplement to, curriculum in Science, Home Economics and Industrial Arts, Mathematics, Health, English, and Social Studies. The topics investigated include: pollution analysis, industrial need,…
Evaluation of putative neurochemical intermediaries in space/motion sickness
NASA Technical Reports Server (NTRS)
Lucot, James B.; Crampton, George H.
1991-01-01
The topics covered include the following: the emetic stimuli used on the cats in the study; analysis of the constituents of the cerebral spinal fluid (CSF) during motion sickness; evaluation of serotonin-1A agonists; other 5-HT receptors; and additional studies and activities.
Hitlerism and the German Universities.
ERIC Educational Resources Information Center
Neuriter, Paul R.
1999-01-01
An author who comes from the German higher education system offers insights into how it differs from the American higher education system and how certain undesirable characteristics may be avoided in the United States. Topics discussed include student independence, lack of extracurricular activities and campus community, tendency toward…
Review of Congressional Issues. News from Capitol Hill.
ERIC Educational Resources Information Center
Heinz, Ann Simeo
2002-01-01
Focuses on U.S. congressional issues in two categories: (1) enacted legislation, and (2) proposed legislation. Addresses topics such as the resolution related to Iraq, the Department of Homeland Security, Pledge of Allegiance, social security protection, elder justice, and women's rights. Includes learning activities. (CMK)
ERIC Educational Resources Information Center
Donovan, Neville
1979-01-01
Provides a survey and a review of earthquake activity and global tectonics from the advancement of the theory of continental drift to the present. Topics include: an identification of the major seismic regions of the earth, seismic measurement techniques, seismic design criteria for buildings, and the prediction of earthquakes. (BT)
Performance Support in Internet Time: The State of the Practice.
ERIC Educational Resources Information Center
Gery, Gloria; Malcolm, Stan; Cichelli, Janet; Christensen, Hal; Raybould, Barry; Rosenberg, Marc J.
2000-01-01
Relates a discussion held via teleconference that addressed trends relating to performance support. Topics include computer-based training versus performance support; knowledge management; Internet and Web-based applications; dynamics and human activities; enterprise application integration; intrinsic performance support; and future possibilities.…
Microscopic Analysis of Activated Sludge. Training Manual.
ERIC Educational Resources Information Center
Office of Water Program Operations (EPA), Cincinnati, OH. National Training and Operational Technology Center.
This training manual presents material on the use of a compound microscope to analyze microscope communities, present in wastewater treatment processes, for operational control. Course topics include: sampling techniques, sample handling, laboratory analysis, identification of organisms, data interpretation, and use of the compound microscope.…
ERIC Educational Resources Information Center
Nash, J. Thomas
1983-01-01
Trends in and factors related to the nuclear industry and nuclear fuel production are discussed. Topics addressed include nuclear reactors, survival of the U.S. uranium industry, production costs, budget cuts by the Department of Energy and U.S. Geological survey for resource studies, mining, and research/development activities. (JN)
NASA Technical Reports Server (NTRS)
Wilcox, R. E. (Compiler)
1983-01-01
Planned research efforts and reorganization of the Project as the Biocatalysis Research Activity are described, including the following topics: electrocatalysts, fluid extraction, ammonia synthesis, biocatalysis, membrane fouling, energy and economic analysis, decarboxylation, microscopic reaction models, plasmid monitoring, and reaction kinetics.
ERIC Educational Resources Information Center
Correy, Therese; And Others
Services to the elderly, institutionalized, and physically and mentally exceptional, who are unable to use the public library in its traditional form, are described in this guide to programs at the Inglewood (California) Public Library. Topics include: (1) overall library goals and activities; (2) functional and organizational structure of…
Using Dandelion Flower Stalks for Gravitropic Studies.
ERIC Educational Resources Information Center
Clifford, Paul E.; Oxlade, Edwin L.
1991-01-01
Activities that use dandelions to show the phenomena of geotropism and autotropism are described. Directions for collecting the stalks and observing the gravitropic response are included. The topics of lag time and bending rates, autotropism, growth rate changes, presentation time, and gravity detection are discussed. (KR)
The Rise in Consumerism: The Year's Work in Serials, 1990.
ERIC Educational Resources Information Center
Lonberger, Jana
1991-01-01
Examines major issues and trends in serials management represented in the literature published during 1990. Topics covered include the pricing crisis; publishing and scholarly communication; cancellation projects; technological developments and alternatives to print; claiming and replacement activities; acquisitions and collection development;…
ERIC Educational Resources Information Center
Insights on Law & Society, 2001
2001-01-01
Provides a lesson plan with activities using the materials presented in this issue of "Insights on Law and Society" as a basis to test students' critical skills. Focuses on the topic of religious freedom and the ideas of James Madison and Patrick Henry on civil order. Includes a student handout. (CMK)
Electro optical system to measure strains at high temperature
NASA Astrophysics Data System (ADS)
Sciammarella, Cesar A.
1991-01-01
The goals of this proposal were to develop a prototype of an electro-optics system for the measurement of strains in structures at high temperatures and to perform a test under field conditions. In the research task section, the topics addressed include: (1) correction of the effect of vibrations and thermal currents by means of an active compensation system; (2) reduction of the speckle noise by means of electronic filter and TV signal reconstruction circuit; (4) compensation of the rigid body motions by mounting the camera in a universal motion system; and (5) removal of phase errors left by the active compensation system by dynamic reading. In the design and construction section, the topics addressed include: (1) preliminary design; (2) final design; (3) software development; (4) signal conditioning; (5) data processing; (6) recorrelation of two holograms in the presence of rigid body motions; and (7) phase extraction using a computer generated image. Testing in the high temperature oven is also addressed.
For Spacious Skies Activity Guide. An Interdisciplinary Approach to the Sky.
ERIC Educational Resources Information Center
Ward, C. Whitney; Borden, Jack
Despite the fact that the sky is the most dominant feature of our surroundings, it plays the role of an unseen background for may objects. It is the intent of this guide to bring about an awareness of the sky to young people. Topics for activities include: (1) "Sky Awareness"; (2) "Compass"; (3) "Hand Lens"; (4) "Prism"; (5) "Binoculars"; (6)…
The Science Teacher: Fall 2007
NASA Astrophysics Data System (ADS)
Long, Steve
2007-11-01
This article reviews chemistry-related articles published in The Science Teacher from January through Summer 2007. Topics featured in these articles include a student activity simulating HPLC separation, inexpensive inquiry activities using film canisters, learning history as student role-play of scientists in the evolution of atomic theory, testing for radon in homes, and using writing to help high school and elementary students learn about gas laws.
Skylab medical experiments altitude test crew observations.
NASA Technical Reports Server (NTRS)
Bobko, K. J.
1973-01-01
The paper deals with the crew's observations during training and the SMEAT 56-day test. Topics covered include the crew's adaptation to the SMEAT environment and medical experiments protocol. Personal observations are made of daily activities surrounding the medical experiments hardware, Skylab clothing, supplementary activities, recreational equipment, food, and waste management. An assessment of these items and their contributions to the Skylab flight program is made.
1992-04-01
history of science using the book Coming of Age in the Milky hay by Timothy Ferris. A summary of their activities and projects is included in section 3...book on the history of science by Timothy Ferris. A series of scientific films was also selected and shown by Dr. Kung. These covered topics such as
Division A Commission 31: Time
NASA Astrophysics Data System (ADS)
Hosokawa, Mizuhiko; Arias, Elisa Felicitas; Manchester, Richard; Tuckey, Philip; Matsakis, Demetrios; Zhang, Shougang; Zharov, Vladimir
2016-04-01
Time is an essential element of fundamental astronomy. In recent years there have been many time-related issues, in scientific and technological aspects as well as in conventions and definitions. At the Commission 31 (Time) business meeting at the XXIX General Assembly, recent progress and many topics, including Pulsar Time Scales WG and Future UTC WG activities, were reviewed and discussed. In this report, we will review the progress of these topics in the past three years. There are many remarkable topics, such as Time scales, Atomic clock development, Time transfer, Future UTC and future redefinition of the second. Among them, scientific highlights are the progress of pulsar time scales and the optical frequency standards. On the other hand, as the social convention, change in the definition of UTC and the second is important.
UVA-UVB Photoprotective Activity of Topical Formulations Containing Morinda citrifolia Extract
Serafini, Mairim Russo; Detoni, Cassia Britto; Menezes, Paula dos Passos; Pereira Filho, Rose Nely; Fortes, Vanessa Silveira; Vieira, Maria José Fonseca; Guterres, Sílvia Stanisçuaski; de Albuquerque Junior, Ricardo Luiz Cavalcanti; Araújo, Adriano Antunes de Souza
2014-01-01
Exposure to solar radiation, particularly its ultraviolet (UV) component, has a variety of harmful effects on human health. Some of these effects include sunburn cell formations, basal and squamous cell cancers, melanoma, cataracts, photoaging of the skin, and immune suppression. The beneficial photoprotective effects of topical formulations with the extract, Morinda citrifolia, have not been investigated. This present study aims to investigate the potential benefits of M. citrifolia topical application on the dorsal skin of mice, exposed to UVA-UVB light. Using 7 days of treatment, [before (baseline values) and 20 h after UV exposure], the thickness, skin barrier damage (TEWL), erythema, and histological alterations were evaluated. The results showed that the formulations containing the extract protected the skin against UV-induced damage. PMID:25133171
Computational Psychotherapy Research: Scaling up the evaluation of patient-provider interactions
Imel, Zac E.; Steyvers, Mark; Atkins, David C.
2014-01-01
In psychotherapy, the patient-provider interaction contains the treatment’s active ingredients. However, the technology for analyzing the content of this interaction has not fundamentally changed in decades, limiting both the scale and specificity of psychotherapy research. New methods are required in order to “scale up” to larger evaluation tasks and “drill down” into the raw linguistic data of patient-therapist interactions. In the current paper we demonstrate the utility of statistical text analysis models called topic models for discovering the underlying linguistic structure in psychotherapy. Topic models identify semantic themes (or topics) in a collection of documents (here, transcripts). We used topic models to summarize and visualize 1,553 psychotherapy and drug therapy (i.e., medication management) transcripts. Results showed that topic models identified clinically relevant content, including affective, content, and intervention related topics. In addition, topic models learned to identify specific types of therapist statements associated with treatment related codes (e.g., different treatment approaches, patient-therapist discussions about the therapeutic relationship). Visualizations of semantic similarity across sessions indicate that topic models identify content that discriminates between broad classes of therapy (e.g., cognitive behavioral therapy vs. psychodynamic therapy). Finally, predictive modeling demonstrated that topic model derived features can classify therapy type with a high degree of accuracy. Computational psychotherapy research has the potential to scale up the study of psychotherapy to thousands of sessions at a time, and we conclude by discussing the implications of computational methods such as topic models for the future of psychotherapy research and practice. PMID:24866972
Computational psychotherapy research: scaling up the evaluation of patient-provider interactions.
Imel, Zac E; Steyvers, Mark; Atkins, David C
2015-03-01
In psychotherapy, the patient-provider interaction contains the treatment's active ingredients. However, the technology for analyzing the content of this interaction has not fundamentally changed in decades, limiting both the scale and specificity of psychotherapy research. New methods are required to "scale up" to larger evaluation tasks and "drill down" into the raw linguistic data of patient-therapist interactions. In the current article, we demonstrate the utility of statistical text analysis models called topic models for discovering the underlying linguistic structure in psychotherapy. Topic models identify semantic themes (or topics) in a collection of documents (here, transcripts). We used topic models to summarize and visualize 1,553 psychotherapy and drug therapy (i.e., medication management) transcripts. Results showed that topic models identified clinically relevant content, including affective, relational, and intervention related topics. In addition, topic models learned to identify specific types of therapist statements associated with treatment-related codes (e.g., different treatment approaches, patient-therapist discussions about the therapeutic relationship). Visualizations of semantic similarity across sessions indicate that topic models identify content that discriminates between broad classes of therapy (e.g., cognitive-behavioral therapy vs. psychodynamic therapy). Finally, predictive modeling demonstrated that topic model-derived features can classify therapy type with a high degree of accuracy. Computational psychotherapy research has the potential to scale up the study of psychotherapy to thousands of sessions at a time. We conclude by discussing the implications of computational methods such as topic models for the future of psychotherapy research and practice. (PsycINFO Database Record (c) 2015 APA, all rights reserved).
APPLICATION OF DRY HAWTHORN (CRATAEGUS OXYACANTHA L.) EXTRACT IN NATURAL TOPICAL FORMULATIONS.
Stelmakiene, Ada; Ramanauskiene, Kristina; Petrikaite, Vilma; Jakstas, Valdas; Briedis, Vitalis
2016-07-01
There is a great potential for a semi-solid preparation for topical application to the skin that would use materials of natural origin not only as an active substance but also as its base. The aim of this research was to model semisolid preparations containing hawthorn extract and to determine the effect of their bases (carriers) on the release of active components from experimental dosage forms, based on the results of the in vitro studies of the bioactivity of hawthorn active components and ex vivo skin penetration studies. The active compounds of hawthorn were indentified and quantified by validated HPLC method. The antimicrobial and anti-radical activity of dry hawthorn extract were evaluated by methods in vitro. The penetration of active substances into the full undamaged human skin was evaluated by method ex vivo. Natural topical composition was chosen according to the results of release of active compounds. Release experiments were performed with modified Franz type diffusion cells. B.ceieus was the most sensitive bacteria for the hawthorn extract. Extract showed antiradical activity, however the penetration was limited. Only traces of hyperoside and isoquercitrin were founded in epidermis. Protective topical preparation with shea butter released 41.4-42.4% of active substances. Four major compounds of dry hawthorn extract were identified. The research showed that extract had antimicrobial and antiradical activity, however compounds of hawthorn stay on the surface of the undamaged human skin. Topical preparation containing beeswax did not release active compounds. Beeswax was identified as suspending agent. Topical preparations released active compounds when shea butter was used instead of beeswax.
NASA Astrophysics Data System (ADS)
Torbert, R.
1992-12-01
The present volume on active experiments in space discusses dynamic trapping of electrons in the Porcupine ionospheric ion beam experiment, plasma wave observations during electron gun experiments on ISEE-1, spatial coherence and electromagnetic wave generation during electron beam experiments in space, and recent experimental measurements of space platform charging at LEO altitudes. Attention is given to high voltage spheres in an unmagnetized plasma, energetic ion emission for active spacecraft control, the collective gyration of a heavy ion cloud in a magnetized plasma, and remote sensing of artificial luminous clouds by lidars. Topics addressed include modulation of the background flux of energetic particles by artificial injection, wave measurements in active experiments on plasma beam injection, field formation around negatively biased solar arrays in the LEO-plasma, and the registration of ELF waves in rocket-satellite experiments with plasma injection.
ElSohly, M A; Harland, E C; Benigni, D A; Waller, C W
1984-06-01
Thirty-two different cannabinoids were tested for their ability to reduce intraocular pressure (IOP) in the rabbit. These included many of delta 9- and delta 8-THC derivatives and metabolites along with other natural and synthetic cannabinoids. In addition, some non-cannabinoid constituents of Cannabis were screened using the same model. All compounds were administered intravenously, while only a few were tested topically in mineral oil. Water soluble derivatives of delta 9- and delta 8-THC were prepared and tested topically in aqueous solution. The data revealed that certain derivatives of delta 9-and delta 8-THC were more active in lowering IOP than the parent cannabinoids. In addition, compounds other than delta 9- and delta 8-THC and their derivatives were shown to have activity.
The Second Conference on Lunar Bases and Space Activities of the 21st Century, volume 1
NASA Technical Reports Server (NTRS)
Mendell, Wendell W. (Editor); Alred, John W. (Editor); Bell, Larry S. (Editor); Cintala, Mark J. (Editor); Crabb, Thomas M. (Editor); Durrett, Robert H. (Editor); Finney, Ben R. (Editor); Franklin, H. Andrew (Editor); French, James R. (Editor); Greenberg, Joel S. (Editor)
1992-01-01
These papers comprise a peer-review selection of presentations by authors from NASA, LPI industry, and academia at the Second Conference (April 1988) on Lunar Bases and Space Activities of the 21st Century, sponsored by the NASA Office of Exploration and the Lunar Planetary Institute. These papers go into more technical depth than did those published from the first NASA-sponsored symposium on the topic, held in 1984. Session topics covered by this volume include (1) design and operation of transportation systems to, in orbit around, and on the Moon, (2) lunar base site selection, (3) design, architecture, construction, and operation of lunar bases and human habitats, and (4) lunar-based scientific research and experimentation in astronomy, exobiology, and lunar geology.
Teten, Amy F; Dagenais, Paul A; Friehe, Mary J
2015-01-01
This study compared the effectiveness of auditory and visual redirections in facilitating topic coherence for persons with Dementia of Alzheimer's Type (DAT). Five persons with moderate stage DAT engaged in conversation with the first author. Three topics related to activities of daily living, recreational activities, food, and grooming, were broached. Each topic was presented three times to each participant: once as a baseline condition, once with auditory redirection to topic, and once with visual redirection to topic. Transcripts of the interactions were scored for overall coherence. Condition was a significant factor in that the DAT participants exhibited better topic maintenance under visual and auditory conditions as opposed to baseline. In general, the performance of the participants was not affected by the topic, except for significantly higher overall coherence ratings for the visually redirected interactions dealing with the topic of food.
Auditory and Visual Cues for Topic Maintenance with Persons Who Exhibit Dementia of Alzheimer's Type
Teten, Amy F.; Dagenais, Paul A.; Friehe, Mary J.
2015-01-01
This study compared the effectiveness of auditory and visual redirections in facilitating topic coherence for persons with Dementia of Alzheimer's Type (DAT). Five persons with moderate stage DAT engaged in conversation with the first author. Three topics related to activities of daily living, recreational activities, food, and grooming, were broached. Each topic was presented three times to each participant: once as a baseline condition, once with auditory redirection to topic, and once with visual redirection to topic. Transcripts of the interactions were scored for overall coherence. Condition was a significant factor in that the DAT participants exhibited better topic maintenance under visual and auditory conditions as opposed to baseline. In general, the performance of the participants was not affected by the topic, except for significantly higher overall coherence ratings for the visually redirected interactions dealing with the topic of food. PMID:26171273
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-19
.... Meeting topics are provided under the SUPPLEMENTARY INFORMATION section of this notice. DATES: The one-day... Topics The SAS meeting topics will include, but are not limited to, the following: (1) Relevant stock... topics will include, but are not limited to, the following: (1) Relevant stock status updates, including...
PNT Activities at NASA Glenn Research Center
NASA Technical Reports Server (NTRS)
Sands, Obed
2017-01-01
This presentation provides a review of Position Navigation and Timing activities at the Glenn Research Center. Topics include 1) contributions to simulation studies for the Space Service Volume of the Global Navigation Satellite System, 2) development and integration efforts for a Software Defined Radio (SDR) waveform for the Space Communications and Navigation (SCaN) testbed, currently onboard the International Space Station and 3) a GPS L5 testbed intended to explore terrain mapping capabilities with communications signals. Future directions are included and a brief discussion of NASA, GRC and the SCAN office.
Hazardous Materials in Marine Transportation: A Practical Course.
ERIC Educational Resources Information Center
Haas, Thomas J.; Kichner, Jerzy J.
1987-01-01
Describes a course offered at the United States Coast Guard Academy that deals with the marine transportation of hazardous materials. Outlines the major topics covered in the course, including marine transportation regulations. Discusses the use of lectures, laboratory demonstrations, and "hands-on" activities in the instructional…
ERIC Educational Resources Information Center
Update on Law-Related Education, 1988
1988-01-01
Presents an activity which uses hypothetical situations to explore the proper boundaries of freedom of expression and the role of the U.S. Supreme Court in interpreting its limits. Appropriate for grades 4-12, the lesson includes such topics as the "clear and present danger" clause, student expression, obscenity, and defamation. (GEA)
Process Design Manual: Wastewater Treatment Facilities for Sewered Small Communities.
ERIC Educational Resources Information Center
Leffel, R. E.; And Others
This manual attempts to describe new treatment methods, and discuss the application of new techniques for more effectively removing a broad spectrum of contaminants from wastewater. Topics covered include: fundamental design considerations, flow equalization, headworks components, clarification of raw wastewater, activated sludge, package plants,…
ERIC Educational Resources Information Center
Reynolds, Karen
1996-01-01
Presents ideas on the use of rainy weather for activities in the earth, life, and physical sciences. Topics include formation and collision of raindrops, amount and distribution of rain, shedding of water by plants, mapping puddles and potholes, rainbow formation, stalking storms online, lightning, and comparing particles in the air before and…
2018-04-18
Employees discuss one of the electric vehicles on display during Kennedy Space Center’s annual Earth Day celebration. The two-day event featured approximately 50 exhibitors offering information on a variety of topics, including electric vehicles, sustainable lighting, renewable energy, Florida-friendly landscaping tips, Florida’s biking trails and more.
ERIC Educational Resources Information Center
Johnson, Frank
Eleven stories describe traditional practices and true adventures of the Tlingit hunters of Southeast Alaska. The stories are accompanied by learning activities and discussion questions for students and are arranged under the headings of bear, mountain goat and deer, and seal and sea lion. Topics include hunting weapons and strategies, bravery,…
78 FR 49282 - Announcement of National Geospatial Advisory Committee Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-13
... academic organizations, was established to advise the Federal Geographic Data Committee on management of... implementation of Office of Management and Budget (OMB) Circular A-16. Topics to be addressed at the meeting include: --Leadership Dialogue --Recent FGDC Activities --Geospatial Platform --NSDI Strategic Plan --3D...
Professional Training for Teachers of the Gifted and Talented. 1984 Digest.
ERIC Educational Resources Information Center
Jenkins-Friedman, Reva; And Others
The digest addresses topics related to professional training for teachers of gifted and talented students. General responsibilities of such teachers include organizing enrichment activities for students and teachers, disseminating information about innovative teaching practices and materials, and promoting integration between regular and special…
NASA Technical Reports Server (NTRS)
Andrews, Sheila Briskin; Kirschenbaum, Audrey
1988-01-01
Operation Liftoff was designed to encourage pupils in the nation's elementary schools to take a greater interest in mathematics and science. Topics addressed include: food, clothing, health, housing, communication, and working. Each unit consists of background information, a teacher printout (lesson plan), and student liftoff (activities) for levels A, B, and C.
Active Learning in the Digital Age Classroom.
ERIC Educational Resources Information Center
Heide, Ann; Henderson, Dale
This book examines the theoretical and practical issues surrounding today's technology-integrated classroom. The chapters cover the following topics: (1) reasons to integrate technology into the classroom, including the changing world, enriched learning and increased productivity, the learner, the workplace, past experience, and future trends; (2)…
ERIC Educational Resources Information Center
Haynes, Gail E.
1991-01-01
A third-semester physics course that covers the topics of atomic physics, the theory of relativity, and nuclear energy is described. Activities that include the phenomenon of radioactivity, field trips to a nuclear power plant, a simulation of a chain reaction, and comparing the size of atomic particles are presented. (KR)
ERIC Educational Resources Information Center
Offspring, 1995
1995-01-01
These two 1995 issues of the journal "Offspring," a publication of the Michigan Council of Cooperative Nursery Schools, cover a variety of topics familiar to nursery school and day care providers including the mission of the publication. Articles are short pieces useful to practitioners and are frequently accompanied by classroom activities.…
Marine Biological Field Techniques.
ERIC Educational Resources Information Center
Awkerman, Gary L.
This publication is designed for use in a standard science curricula to develop oceanologic manifestations of certain science topics. Included are teacher guides, student activities, and demonstrations designed to impart ocean science understanding to high school students. It could be a useful instructional tool for any high school student field…
[Land Use Unit, Edmonds School District.
ERIC Educational Resources Information Center
Edmonds School District 15, Lynnwood, WA.
This interdisciplinary program, developed for secondary students, contains 18 land use activities that can either be used directly in, or as a supplement to, curriculum in Science, Biology, Horticulture, Mathematics, Social Studies, English, Industrial Arts and Physical Education. The topics to be investigated include: land use simulation games,…
Returning Fourth-Year Students to the Classroom/Laboratory.
ERIC Educational Resources Information Center
Markert, Ronald J.; Ogilvie, Charles D.
1980-01-01
The Eighth Semester Program of the Texas College of Osteopathic Medicine reintroduces classroom-laboratory activities into the medical students' clinical years in an attempt to "round out" students' education. Topics include development of a medical practice, government and the physician, counseling skills, and nutrition inpatient care.…
Theme: Is Problem-Solving Teaching and SAE Needed in Agricultural Education in the 21st Century?
ERIC Educational Resources Information Center
Wardlow, George, Ed.
1999-01-01
Nine articles in this theme issue address problem-solving teaching and supervised agricultural experience. Topics covered include systems approaches to SAE, SAE for Y2K, SAE for science, applied SAE, types of SAE, and examples of activities. (JOW)
CONFERENCE SUMMARY: PRACTICAL ASPECTS OF THE DESIGN AND USE OF GAC
This article is based on papers presented at a 1989 conference on the design and use of granular activated carbon (GAC) systems. The conference was cosponsored by the AWWA Research Foundation and the US Environmental Protection Agency. Topics covered include reasons for the use...
ERIC Educational Resources Information Center
Halton County Board of Education, Burlington (Ontario).
This is a collection of mathematics laboratory activities related to the topics of linear and square measure. There are a number of experimental situations from which results may be generalized. Also included are worksheets, examples and discussion questions which are based on practical situations whenever possible. The materials are for student…
Focus on Library Media Skills for the Young Reader.
ERIC Educational Resources Information Center
School Library Media Activities Monthly, 1989
1989-01-01
Offers suggestions relating to the general characteristics of young readers to aid library media specialists in effective teaching and communication. Topics discussed include physical access, dependence, and activity levels; the use of games and dramatic play; children's interests; conceptual development; and emotional needs and behaviors. (CLB)
ERIC Educational Resources Information Center
Greene, H. David; And Others
Designed to meet the diverse educational needs of youth groups, this aquatic program consists of eight individual lesson units, each devoted to one aspect of the aquatic world. Unit topics include: fish aquariums; raising earthworms; simulation of coastal planning; entomology and water; rope; calculating stream flow; saltwater aquariums; and fish…
Dispersion model studies for Space Shuttle environmental effects activities
NASA Technical Reports Server (NTRS)
1981-01-01
The NASA/MSFC REED computer code was developed for predicting concentrations, dosage, and deposition downwind from rocket vehicle launches. The calculation procedures and results of nine studies using the code are presented. Topics include plume expansion, hydrazine concentrations, and hazard calculations for postulated fuel spills.
The Bradford Papers Annual, Volume III, 1988.
ERIC Educational Resources Information Center
Robb, Gary M., Ed.
This annual collection promotes scholarly writing, applied research findings, and innovative programs and activities in experiential education. Topics of the 1988 papers include (1) "Gender Issues in Outdoor Adventure Programming" (Natalie L. Bartley and Daniel R. Williams) about the effects of outdoor leaders' gender, personality, soft skills…
Mennonite Nursing Home passive solar demonstration
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
A long-term nursing care facility and retirement center was designed for passive solar heating. The system comprises thermal mass, thermal insulation, Trombe walls, and direct gain clerestories. Included here is a topical report, analysis of building performance, owner's perspective, designer's perspective, and summary of information dissemination activities. (MHR)
Practice and Malpractice in Philosophy of Education.
ERIC Educational Resources Information Center
Popp, Jerome A.
1978-01-01
Examines educational philosophy as an area of inquiry in light of several points of view from other areas of philosophic inquiry. Topics discussed include activities engaged in by philosophers, analogues in science, theoretical vs practical inquiry, epistemic utilities in philosophy, and the scientific context of educational philosophizing. (DB)
Workshop report: US-China workshop on smart structures and smart systems
NASA Astrophysics Data System (ADS)
Tomizuka, Masayoshi
2006-03-01
A Joint U.S.-China workshop on the topic of Integrated Sensing Systems, Mechatronics and Smart Structures Technologies was held in Jinan, China in October 2005 to evaluate the current status of research and education in the topic areas in the United States and China, to identify critical and strategic research and educational issues of mutual interest, and to identify joint research projects and potential research teams for collaborative research activities. The workshop included a series of presentations by leading researchers and educators from the United States and China and group discussions on the workshop objectives.
Face washing promotion for preventing active trachoma
Ejere, Henry OD; Alhassan, Mahmoud B; Rabiu, Mansur
2015-01-01
Background Trachoma remains a major cause of avoidable blindness among underprivileged populations in many developing countries. It is estimated that about 146 million people have active trachoma and nearly six million people are blind due to complications associated with repeat infections. Objectives The objective of this review was to assess the effects of face washing promotion for the prevention of active trachoma in endemic communities. Search methods We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (2015, Issue 1), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to January 2015), EMBASE (January 1980 to January 2015), PubMed (January 1948 to January 2015), Latin American and Caribbean Health Sciences Literature Database (LILACS) (January 1982 to January 2015), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com) (accessed 10 January 2014), ClinicalTrials.gov (www.clinicaltrials.gov) and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 26 January 2015. To identify further relevant trials we checked the reference lists of the included trials. Also, we used the Science Citation Index to search for references to publications that cited the trials included in the review. We contacted investigators and experts in the field to identify additional trials. Selection criteria We included randomized controlled trials (RCTs) or quasi-RCTs that compared face washing with no treatment or face washing combined with antibiotics against antibiotics alone. Trial participants were residents of endemic trachoma communities. Data collection and analysis Two review authors independently extracted data and assessed trial quality. We contacted trial authors for additional information when needed. Two trials met our inclusion criteria; but we did not conduct meta-analysis due to methodological heterogeneity. Main results We included two cluster-RCTs, which provided data from 2447 participants. Both trials were conducted in areas endemic to trachoma: Northern Australia and Tanzania. The follow-up period was three months in one trial and 12 months in the other; both trials had about 90% participant follow-up at final visit. Overall the quality of the evidence is uncertain due to the trials not reporting many design methods and the differences in outcomes reported between trials. Face washing combined with topical tetracycline was compared with topical tetracycline alone in three pairs of villages in one trial. The trial found that face washing combined with topical tetracycline reduced ’severe’ active trachoma compared with topical tetracycline alone at 12 months (adjusted odds ratio (OR) 0.62, 95% confidence interval (CI) 0.40 to 0.97); however, the trial did not find any important difference between the intervention and control villages in reducing other types of active trachoma (adjusted OR 0.81, 95% CI 0.42 to 1.59). Intervention villages had a higher prevalence of clean faces than the control villages among children with severe trachoma (adjusted OR 0.35, 95% CI 0.21 to 0.59) and any trachoma (adjusted OR 0.58, 95% CI 0.47 to 0.72) at 12 months follow-up. The second trial compared eye washing to no treatment or to topical tetracycline alone or to a combination of eye washing and tetracycline drops in children with follicular trachoma. At three months, the trial found no evidence of benefit of eye washing alone or in combination with tetracycline eye drops in reducing follicular trachoma amongst children with follicular trachoma (risk ratio (RR) 1.03, 95% CI 0.96 to 1.11; one trial, 1143 participants). Authors’ conclusions There is evidence from one trial that face washing combined with topical tetracycline may be effective in reducing severe active trachoma and in increasing the prevalence of clean faces at one year follow-up. Current evidence is inconclusive as to the effectiveness of face washing alone or in combination with topical tetracycline in reducing active or severe trachoma. PMID:25697765
2016-01-01
A commitment to regular physical activity may reduce the risks of chronic diseases for young adults. Internationally, the majority of post-secondary students are insufficiently active for health benefits. Novel health strategies and interventions utilizing mobiles phones could increase post-secondary students’ physical activity levels. However, there is contradictory evidence to support the use of mobile phones to promote physical activity, and a scoping review could provide further insights into this topic. The purpose of this study was to conduct a scoping review to explore the existing literature and investigate what is currently known about the use of mobile phones to enhance physical activity levels among post-secondary students. A total of 84 articles were identified from the literature search, and six studies were selected for data analysis. Two major themes were supported by the evidence, which included: (I) the relationship between mobile phones and physical activity levels; and (II) students’ perceptions of mobile phones. Goal setting principles combined with text message interventions were reported to have significant influences on students’ physical activity levels. Students expressed mixed feelings about coaching elements of apps and posting personal results on social networking websites. No studies reported the use of objective physical activity measurements. In conclusion, mobile phone technologies such as text message reminders could be included in health interventions to enhance post-secondary students’ physical activity levels. There is limited evidence available on this topic and additional research is warranted to establish a clearer understanding of the relationship between mobile phones and post-secondary students’ physical activity. PMID:28293617
Ly, Hieu
2016-01-01
A commitment to regular physical activity may reduce the risks of chronic diseases for young adults. Internationally, the majority of post-secondary students are insufficiently active for health benefits. Novel health strategies and interventions utilizing mobiles phones could increase post-secondary students' physical activity levels. However, there is contradictory evidence to support the use of mobile phones to promote physical activity, and a scoping review could provide further insights into this topic. The purpose of this study was to conduct a scoping review to explore the existing literature and investigate what is currently known about the use of mobile phones to enhance physical activity levels among post-secondary students. A total of 84 articles were identified from the literature search, and six studies were selected for data analysis. Two major themes were supported by the evidence, which included: (I) the relationship between mobile phones and physical activity levels; and (II) students' perceptions of mobile phones. Goal setting principles combined with text message interventions were reported to have significant influences on students' physical activity levels. Students expressed mixed feelings about coaching elements of apps and posting personal results on social networking websites. No studies reported the use of objective physical activity measurements. In conclusion, mobile phone technologies such as text message reminders could be included in health interventions to enhance post-secondary students' physical activity levels. There is limited evidence available on this topic and additional research is warranted to establish a clearer understanding of the relationship between mobile phones and post-secondary students' physical activity.
Using PLSI-U To Detect Insider Threats from Email Traffic
NASA Astrophysics Data System (ADS)
Okolica, James; Peterson, Gilbert; Mills, Robert
Despite a technology bias that focuses on external electronic threats, insiders pose the greatest threat to commercial and government organizations. Once information on a specific topic has gone missing, being able to quickly determine who has shown an interest in that topic can allow investigators to focus their attention. Even more promising is when individuals can be found who have an interest in the topic but who have never communicated that interest within the organization. An employee's interests can be discerned by data mining corporate email correspondence. These interests can be used to construct social networks that graphically expose investigative leads. This paper describes the use of Probabilistic Latent Semantic Indexing (PLSI) [4] extended to include users (PLSI-U) to determine topics that are of interest to employees from their email activity. It then applies PLSI-U to the Enron email corpus and finds a small number of employees (0.02%) who appear to have had clandestine interests.
Brennan, Frank R; Baumann, Andreas; Blaich, Guenter; de Haan, Lolke; Fagg, Rajni; Kiessling, Andrea; Kronenberg, Sven; Locher, Mathias; Milton, Mark; Tibbitts, Jay; Ulrich, Peter; Weir, Lucinda
2015-10-01
Non-clinical safety testing of biopharmaceuticals can present significant challenges to human risk assessment with these often innovative and complex drugs. Hot Topics in this field were discussed recently at the 4th Annual European Biosafe General Membership meeting. In this feature article, the presentations and subsequent discussions from the main sessions are summarized. The topics covered include: (i) wanted versus unwanted immune activation, (ii) bi-specific protein scaffolds, (iii) use of Pharmacokinetic (PK)/Pharmacodynamic (PD) data to impact/optimize toxicology study design, (iv) cytokine release and challenges to human translation (v) safety testing of cell and gene therapies including chimeric antigen receptor T (CAR-T) cells and retroviral vectors and (vi) biopharmaceutical development strategies encompassing a range of diverse topics including optimizing entry of monoclonal antibodies (mAbs) into the brain, safety testing of therapeutic vaccines, non-clinical testing of biosimilars, infection in toxicology studies with immunomodulators and challenges to human risk assessment, maternal and infant anti-drug antibody (ADA) development and impact in non-human primate (NHP) developmental toxicity studies, and a summary of an NC3Rs workshop on the future vision for non-clinical safety assessment of biopharmaceuticals. Copyright © 2015 Elsevier Inc. All rights reserved.
Murrell, Dedee F; Gebauer, Kurt; Spelman, Lynda; Zane, Lee T
2015-10-01
A novel approach for treating atopic dermatitis (AD) is the inhibition of phosphodiesterase 4 (PDE4), an enzyme involved in the proinflammatory cascade. Crisaborole topical ointment, 2% is a novel, boron-based small-molecule PDE4 inhibitor with anti-inflammatory properties. The objective of this proof-of-concept study was to assess the efficacy and safety of crisaborole topical ointment, 2% in adults with mild to moderate AD. This phase 2a, randomized, double-blind, bilateral, 6-week study of crisaborole topical ointment, 2% was conducted in adult patients with mild to moderate AD with 2 comparable target AD lesions. Patients were randomly assigned to twice-daily application of crisaborole topical ointment, 2% or vehicle, each to 1 of the 2 target lesions. The primary efficacy endpoint was change from baseline in Atopic Dermatitis Severity Index (ADSI) score at day 28. Safety assessments included local tolerability and incidence of adverse events (AEs). A total of 25 enrolled patients received study medication. At day 28, 17 patients (68%) experienced a greater decrease in ADSI score in the active-treated lesion than in the vehicle-treated lesion; 5 patients (20%) had a greater decrease in ADSI score in the vehicle-treated lesion than in the active-treated lesion. Local application-site reactions were reported in 3 patients (12%). A total of 29 AEs were reported in 11 patients; most (90%) were mild in intensity and unrelated to study medication. No serious or severe AEs were reported, and no patient discontinued due to an AE. These findings provide preliminary evidence of the efficacy and safety of treatment with crisaborole topical ointment, 2% in adults with mild to moderate AD. The study is registered on ClinicalTrials.gov (identifier NCT01301508).
NASA Technical Reports Server (NTRS)
Coffey, H. E. (Editor)
1985-01-01
Topics covered include: detailed index for 1985; data for August 1985--(IUWDS alert periods (Advanced and Worldwide), solar activity indices, solar flares, solar radio emission, Stanford mean solar magnetic field); (solar active regions, sudden ionospheric disturbances, solar radio spectral observations, cosmic ray measurements by neutron monitor, geomagnetic indices, radio propagation indices); and late data--calcium plage data.
ERIC Educational Resources Information Center
Stevens, Lawrence
This unit focuses on the decades of the 1940s and 1950s by studying key events from the eras. Students analyze issues and think critically about decisions made during the time. Topics of the unit include: (1) "Japanese Relocation"; (2) "Rationing: Who Should Get What?"; (3) "War in the Pacific"; (4) "The Draft: Who Should Fight a War?"; (5)…
The NEED (National Energy Education Development) Project
NASA Astrophysics Data System (ADS)
Hogan, D.; Spruill, M.
2012-04-01
The NEED (National Energy Education Development) Project is a non-profit organization which provides a wide range of K-12 curriculum on energy education topics. The curriculum is specific for primary, elementary, intermediate and secondary levels with age appropriate activities and reading levels. The NEED Project covers a wide range of topics from wind energy, nuclear energy, solar energy, hydropower, hydrogen, fossil fuels, energy conservation, energy efficiency and much more. One of the major strengths of this organization is its Teacher Advisory Board. The curriculum is routinely revised and updated by master classroom teachers who use the lessons and serve on the advisory board. This ensures it is of the highest quality and a useful resource. The NEED Project through a variety of sponsors including businesses, utility companies and government agencies conducts hundreds of teacher professional development workshops each year throughout the United States and have even done some workshops internationally. These workshops are run by trained NEED facilitators. At the workshops, teachers gain background understanding of the energy topics and have time to complete the hands on activities which make up the curriculum. The teachers are then sent a kit of equipment after successfully completing the workshop. This allows them to teach the curriculum and have their students perform the hands on labs and activities in the classroom. The NEED Project is the largest provider of energy education related curriculum in the United States. Their efforts are educating teachers about energy topics and in turn educating students in the hope of developing citizens who are energy literate. Many of the hands on activities used to teach about various energy sources will be described and demonstrated.
Ford, Alexander C; Khan, Khurram J; Achkar, Jean-Paul; Moayyedi, Paul
2012-02-01
Efficacy of 5-aminosalicylic acids (5-ASAs) in ulcerative colitis (UC) has been studied previously in meta-analyses. However, no recent meta-analysis has studied the relative efficacies of differing routes of administration. MEDLINE, EMBASE, and the Cochrane central register of controlled trials were searched (through May 2011). Eligible trials recruited adults with mildly to moderately active UC, or quiescent UC, and compared oral 5-ASAs with either topical 5-ASAs or a combination of oral and topical 5-ASAs. Dichotomous data were pooled to obtain relative risk (RR) of failure to achieve remission in active UC, and RR of relapse of disease activity in quiescent UC, with a 95% confidence interval (CI). The number needed to treat (NNT) was calculated from the reciprocal of the risk difference. The search identified 3,061 citations, and 12 randomized controlled trials (RCTs) were eligible. Four compared topical with oral 5-ASAs in active UC remission, with an RR of no remission with topical 5-ASAs of 0.82 (95% CI=0.52-1.28). Four trials compared combined with oral 5-ASAs in active UC (RR of no remission=0.65; 95% CI=0.47-0.91; NNT=5). Three RCTs compared intermittent topical with oral 5-ASAs in preventing relapse of quiescent UC (RR=0.64; 95% CI=0.43-0.95; NNT=4), and two compared combined with oral 5-ASAs (RR of relapse=0.48; 95% CI=0.17-1.38). Combined 5-ASA therapy appeared superior to oral 5-ASAs for induction of remission of mildly to moderately active UC. Intermittent topical 5-ASAs appeared superior to oral 5-ASAs for preventing relapse of quiescent UC.
Nurse teacherhood: systematic descriptive review and content analysis.
Holopainen, Arja; Hakulinen-Viitanen, Tuovi; Tossavainen, Kerttu
2007-05-01
The concept of 'nurse teacherhood' is multidimensional. In this article, 'nurse teacherhood' includes nurse teachers' tasks and different multidimensional roles as well as their personal experiences of being a nurse teacher. The article examines the topics of nursing research concerning nurse teacherhood, the changes in these topics and the results reported from January 1990 to April 2004. The material was obtained by conducting a systematic review, and it included nursing research papers and Finnish academic dissertations (N=207). The material was analysed by using content analysis. The topics of the studies were divided into three thematic categories: the expansion of nurse teacherhood, the skills of nurse teacherhood and their development, nurse teacherhood and membership in working community. The number of studies on the first two themes had increased (1990-1994:43; 1995-1999:57; 2000-4/2004:65), while those on the third theme had decreased (1990-1994:18; 1995-1999:19; 2000-4/2004:5). Nurse teacherhood has been studied actively during the past 15 years and approached from several perspectives. Most of the topics of the studies discussed the expansion of nurse teacherhood. The focus of the studies in different years varied depending on the kind of challenges posed to nurse teachers' work in each period of time.
Reporting from the Iceland Deep Drilling Project
NASA Astrophysics Data System (ADS)
Urban, Karl
2017-04-01
Geoscience-related topics are in many cases difficult to communicate to the public: Often they include dead soil which not easily tells lively stories. And it is hard to sell those topics to editors of public media. In addition the topics might also be politically supercharged if they are resource-related with a visible environmental impact. Therefore any researcher involved might be overcautious while talking to journalists. With a grant from the EGU Science Journalist Fellowship I travelled to Iceland in autumn 2016 to report about the Iceland Deep Drilling Project (IDDP). The project which started just weeks prior to my arrival aimed to drill the deepest borehole in a volcanically active region. During earlier trials the borehole collapsed or the drill string unintentionally hit magma. If successful the IDDP promises a much higher level of geothermal energy harvested. The IDDP was therefore ideally suited to be sold to public media outlets since Iceland's volcanic legacy easily tells a lively story. But the drilling's potential environmental impact makes it a political topic in Iceland - even though geothermal energy has a positive public perception. Therefore the IDDP included some pitfalls I observed several times before while reporting about geoscience research. Those could be circumvented if researchers and journalists knew better about their expectations before any interview takes place.
Vitiligo: An Update on Pathophysiology and Treatment Options.
Speeckaert, Reinhart; van Geel, Nanja
2017-12-01
The pathophysiology of vitiligo is becoming increasingly clarified. In non-segmental vitiligo, early factors include activation of innate immunity, inflammasome activation, oxidative stress, and loss of melanocyte adhesion. Nonetheless, the main mechanism leading to non-segmental vitiligo involves an immune-mediated destruction of melanocytes. Anti-melanocyte-specific cytotoxic T cells exert a central role in the final effector stage. Genetic research revealed a multi-genetic inheritance displaying an overlap with other autoimmune disorders. However, some melanocyte-specific genes were also affected. Segmental vitiligo carries a different pathogenesis with most evidence indicating a mosaic skin disorder. Current management includes topical corticosteroids and immunomodulators. Narrow-band ultraviolet B can be used in patients not responding to topical treatment or in patients with extensive disease. Pigment cell transplantation offers an alternative for the treatment of segmental vitiligo or stable non-segmental lesions. Recent findings have revealed new targets for treatment that could lead to more efficient therapies. Targeted immunotherapy may halt the active immune pathways, although combination therapy may still be required to induce satisfying repigmentation. A recently established core set of outcome measures, new measurement instruments, and biomarker research pave the way for future standardized clinical trials.
Topical Treatment of Degenerative Knee Osteoarthritis.
Meng, Zengdong; Huang, Rongzhong
2018-01-01
This article reviews topical management strategies for degenerative osteoarthritis (OA) of the knee. A search of Pubmed, Embase and the Cochrane library using MeSH terms including "topical," "treatment," "knee" and "osteoarthritis" was carried out. Original research and review articles on the effectiveness and safety, recommendations from international published guidelines and acceptability studies of topical preparations were included. Current topical treatments included for the management of knee OA include topical nonsteroidal anti-inflammatory drugs, capsaicin, salicylates and physical treatments such as hot or cold therapy. Current treatment guidelines recommend topical nonsteroidal anti-inflammatory drugs as an alternative and even first-line therapy for OA management, especially among elderly patients. Guidelines on other topical treatments vary, from recommendations against their use, to in favor as alternative or simultaneous therapy, especially for patients with contraindications to other analgesics. Although often well-tolerated and preferred by many patients, clinical care still lags in the adoption of topical treatments. Aspects of efficacy, safety and patient quality of life data require further research. Copyright © 2018 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.
Lunar Regolith Biomining: Workshop Report
NASA Technical Reports Server (NTRS)
Dalton, Bonnie P.; Roberto, Frank F.
2008-01-01
On May 5th and 6th, 2007, NASA Ames Research Center hosted a workshop entitled 'Lunar Regolith Biomining'. The workshop addressed the feasibility of biologically-based mining of the lunar regolith along with identification of views and concepts for moving this topic forward to NASA. Workshop presentations provided background in topics of interest that served as the foundation for discussion in the subsequent breakout sessions. The first topical area included the history, status, and issues with biomining on Earth to familiarize all attendees with current activities. These presentations related the primary considerations in existing biomining, e.g., microbes of choice, pH of reactions, time and temperature, specific mining applications and locations, and benefits and/or limitations of biomining. The second area reviewed existing research efforts addressing biomining of planetary surfaces (Mars, Moon), including microbial considerations, and chemical necessities in biomining and biofuel production. The last element pertained to other non-biological considerations and influences in biomining efforts on the lunar surface such as radiation fluxes and effects, and the application of small satellite experiments to learn more about the lunar and Martian surfaces. Following the presentations, the workshop attendees divided into three breakout sessions to discuss areas of interest in greater detail and to define next steps in determining the feasibility of lunar regolith biomining. Topics for each of the three breakout sessions included: 1) bio-communities of choice, target product(s), and suggested ground studies; 2) physical/environmental issues and ground studies; and 3) the development of reference experiments for the Astrobiology Small payloads Workshop. The results of the breakout sessions are summarized and a list of participants is included.
ERIC Educational Resources Information Center
Urshan, J.
This guide to supermarket shopping provides information in an outline format. It first covers preliminary activities such as determining family needs, shopping on a budget, and planning at home. A number of suggestions are then made for the actual shopping. Topics include shopper aids (unit pricing, nutritional labeling, freshness coding), store…
Women and Mental Health: Augmenting Undergraduates' Knowledge and Critical Thinking.
ERIC Educational Resources Information Center
Gibson, Pamela Reed
1992-01-01
Describes an undergraduate course in psychology that addresses concepts relating to women's mental health. Explains that the course emphasizes the impact of social variables on mental health issues for women. Includes a list of topics and student activities for the course. Presents student reactions and assessment. (DK)
In-Service Training Materials for Teachers of the Educable Mentally Retarded. Session III.
ERIC Educational Resources Information Center
Meyen, Edward L.; Carr, Donald L.
Supplementing language arts for the educable mentally handicapped, the guide provides a representative unit on newspapers with core area activities, vocabulary, and 33 lesson plans. Sub-topics include community orientation, occupations, leisure time and recreation, weather, local history, money management, homemaking and home repair,…
Intermountain Leisure Symposium Proceedings (6th, Logan, UT, November 7, 1985).
ERIC Educational Resources Information Center
Gray, Howard, Ed.
Topics covered in this symposium included: (1) a perspective for seeking commercial sponsorships; (2) developing an activity program that perpetuates developmental skills; (3) emerging American lifestyles: implications for park and recreation professionals; (4) clinical hypnosis: a possible adjunct to therapeutic recreation; (5) impact fees for…
CNN Newsroom Classroom Guides. March 1-31, 1996.
ERIC Educational Resources Information Center
Cable News Network, Atlanta, GA.
These classroom guides, designed to accompany the daily CNN (Cable News Network) Newsroom broadcasts for the month of March, provide program rundowns, suggestions for class activities and discussion, student handouts, and a list of related news terms. Topics include: negative campaign ads, the end of the Sarajevo siege, alternative medicine in…
Grants and Contracts Handbook.
ERIC Educational Resources Information Center
Holman, Paul C.
One of the roles of administration is to assist the faculty and staff of an institution in the development and administration of grants. A portion of this role includes fulfilling an obligation to sponsors who have furnished funding for vital activities by providing administrative direction. Covering such topics as preparing an application, tax…
Fiber, Fabric and Fashion. Environment II.
ERIC Educational Resources Information Center
Arizona State Univ., Tempe.
A competency-based instructional guide for grades 7-14, this volume is one of three parts, each of which focuses on a different environment (psychomotor, cognitive, or affective), and each of which includes competencies and learning activities for each of three instructional levels. The topics for this volume (Environment II--cognitive) are…
CNN Newsroom Classroom Guides. May 2-31, 1994.
ERIC Educational Resources Information Center
Cable News Network, Atlanta, GA.
These classroom guides for the daily CNN (Cable News Network) Newsroom broadcasts for the month of May provide program rundowns, suggestions for class activities and discussion, student handouts, and a list of related news terms. Topics covered by the guides include: (1) the Palestinian Liberation Organization (PLO) and Palestine, Hawaiian…
CNN Newsroom Guides: April 3-28, 1995.
ERIC Educational Resources Information Center
Cable News Network, Atlanta, GA.
These classroom guides for the daily Cable News Network (CNN) Newsroom broadcasts for the month of April provide program rundowns, suggestions for class activities and discussion, student handouts, and a list of related news terms. Topics covered by the guide include: (1) reckless driving, hearing impairment, ancient to modern cities,…
Development of a British Road Safety Education Support Materials Curriculum.
ERIC Educational Resources Information Center
Bouck, Linda H.
Road safety education needs to be a vital component in the school curriculum. This paper describes a planned road safety education support materials curriculum developed to aid educators in the Wiltshire County (England) primary schools. Teaching strategies include topic webs, lecture, class discussion, group activities, and investigative learning…
CNN Newsroom Classroom Guides. January 1-31, 1997.
ERIC Educational Resources Information Center
Cable News Network, Atlanta, GA.
These classroom guides, designed to accompany the daily CNN (Cable News Network) Newsroom broadcasts for the month of January, provide program rundowns, suggestions for class activities and discussion, student handouts, and a list of related news terms. Topics include: U.S. House of Representatives prepares for ethics battle, diplomatic immunity,…
2018-04-18
An array of electric vehicles are on display for Kennedy Space Center employees during the center’s annual Earth Day celebration. The two-day event featured approximately 50 exhibitors offering information on a variety of topics, including electric vehicles, sustainable lighting, renewable energy, Florida-friendly landscaping tips, Florida’s biking trails and more.
2018-04-17
During the annual Earth Day celebration at the Kennedy Space Center Visitor Complex, guests have an opportunity to learn about the environment. The two-day event featured approximately 50 exhibitors offering information on a variety of topics, including electric vehicles, sustainable lighting, renewable energy, Florida-friendly landscaping tips, Florida’s biking trails and more.
ERIC Educational Resources Information Center
Durkin, Lisa Lyons, Ed.
1997-01-01
These six theme-oriented newsletter issues present specific curriculum planning ideas and activities for teachers of young children. The theme of the January-February 1997 issue is "The Arts of Winter." Topics in this issue include celebrating with music and movement, learning songs, classroom visitors and the arts, art in picture books,…
A Simulation of an Energy-Efficient Home.
ERIC Educational Resources Information Center
McLeod, Richard J.; And Others
1981-01-01
A shoe box is converted into a model home to demonstrate the energy efficiency of various insulation measures. Included are instructions for constructing the model home from a shoe box, insulating the shoe box, several activities involving different insulation measures, extensions of the experiment, and post-lab discussion topics. (DS)
CNN Newsroom Guides. March 1-31, 1995.
ERIC Educational Resources Information Center
Cable News Network, Atlanta, GA.
These classroom guides for the daily Cable News Network (CNN) Newsroom broadcasts for the month of March provide program rundowns, suggestions for class activities and discussion, student handouts, and a list of related news terms. Topics covered by the guide include: (1) investment terminology, Republican presidential nominations, the shuttle…
2018-04-18
Employees stop by the University of Florida's Institute of Food and Agricultural Sciences booth at Kennedy Space Center’s annual Earth Day celebration. The two-day event featured approximately 50 exhibitors offering information on a variety of topics, including electric vehicles, sustainable lighting, renewable energy, Florida-friendly landscaping tips, Florida’s biking trails and more.
CNN Newsroom Classroom Guides. March 1-31, 1997.
ERIC Educational Resources Information Center
Cable News Network, Atlanta, GA.
These classroom guides, designed to accompany the daily CNN (Cable News Network) Newsroom broadcasts for the month of March, provide program rundowns, suggestions for class activities and discussion, student handouts, and a list of related news terms. Topics include: monkeys cloned in Oregon, Iran suffers massive earthquake, tornados affect…
76 FR 59395 - Notice of Webcast Meeting of the Environmental Financial Advisory Board (EFAB)
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-26
... creative approaches to funding environmental programs, projects, and activities. The purpose of the meeting... priorities and to discuss progress with work projects under EFAB's current Strategic Action Agenda; and... topics expected to be discussed include: financing clean air technology; financing tribal environmental...
76 FR 7844 - Notice of Open Meeting of the Environmental Financial Advisory Board (EFAB)
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-11
... environmental programs, projects, and activities. The purpose of the meeting is to hear from informed speakers... work projects under EFAB's current Strategic Action Agenda. Environmental Finance topics expected to be discussed include: Financing Clean Air Technology; Voluntary Environmental Improvement Bonds (VEIB)/Property...
Review of Issues Facing Congress. News from Capitol Hill.
ERIC Educational Resources Information Center
Heinz, Ann Simeo
2001-01-01
Discusses various topics that have faced the 107th U.S. Congress, such as tax cuts, judicial appointments, domestic issues, patients' bill of rights, stem cell research, election law, and campaign finance reform. Includes information on U.S. Senate and federal judicial appointments. Provides ideas for student learning activities. (CMK)
CNN Newsroom Classroom Guides. December 1-31, 1997.
ERIC Educational Resources Information Center
Cable News Network, Atlanta, GA.
These classroom guides, designed to accompany the daily CNN (Cable News Network) Newsroom broadcasts for the month of December, provide program rundowns, suggestions for class activities and discussion, student handouts, and a list of related news terms. Topics include: Japan hosts the Climate Change Conference, space shuttle is unable to deploy…
Synergy across the Curriculum: Simulating the Institution of Postwar Iraqi Government
ERIC Educational Resources Information Center
Austin, W. Chadwick; McDowell, Todd; Sacko, David H.
2006-01-01
This article describes an undergraduate simulation that formulates Iraqi regimes following the removal of Saddam Hussein's Baathist regime. This exercise reinforces student comprehension and awareness for a range of legal and political topics--including group decision making, international law, diplomacy, and human rights--by actively engaging the…