Science.gov

Sample records for actual exit velocity

  1. Relationship between cattle temperament as determined by exit velocity carcass merit in beef cattle

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The objective of this trial was to use cattle temperament, as determined by exit velocity only, as a means to evaluate the impact of temperament on carcass merit and the possible utilization of exit velocity alone as a sorting tool within the feedlot. At the time of processing, exit velocity and bod...

  2. Effect of cattle temperament as determined by exit velocity on lung respiratory lesions and liver disease

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The objective of this trial was to use exit velocity as a means of determining temperament of cattle to evaluate the impact of temperament on animal health. At the time of processing, exit velocity and body weight were recorded on 20 pens of cattle (2,877 head) at a commercial feedlot. Infrared sens...

  3. Control of exit velocity profile of an asymmetric annular diffuser using wall suction

    NASA Technical Reports Server (NTRS)

    Juhasz, A. J.

    1973-01-01

    An asymmetric annular diffuser equipped with wall bleed (suction) capability was tested for controllability of exit velocity profile. The diffuser area ratio was 3.2, and the length to inlet height ratio was 1.6. Results show that the diffuser radial exit velocity profile could be controlled from a hub peaked to a tip peaked form by selective use of bleed on the outer wall or on both diffuser walls. Based on these results, application of the diffuser bleed technique to gas turbine combustors may be possible. Diffuser bleed could be used to tailor the airflow distribution for optimizing combustor performance at a variety of operating conditions.

  4. Effect of velocity and temperature distribution at the hole exit on film cooling of turbine blades

    NASA Technical Reports Server (NTRS)

    Garg, Vijay K.; Gaugler, Raymond E.

    1995-01-01

    An existing three-dimensional Navier-Stokes code, modified to include film cooling considerations, has been used to study the effect of coolant velocity and temperature distribution at the hole exit on the heat transfer coefficient on three-film-cooled turbine blades, namely, the C3X vane, the VKI rotor, and the ACE rotor. Results are also compared with the experimental data for all the blades. Moreover, Mayle's transition criterion, Forest's model for augmentation of leading edge heat transfer due to freestream turbulence, and Crawford's model for augmentation of eddy viscosity due to film cooling are used. Use of Mayle's and Forest's models is relevant only for the ACE rotor due to the absence of showerhead cooling on this rotor. It is found that, in some cases, the effect of distribution of coolant velocity and temperature at the hole exit can be as much as 60% on the heat transfer coefficient at the blade suction surface, and 50% at the pressure surface. Also, different effects are observed on the pressure and suction surface depending upon the blade as well as upon the hole shape, conical or cylindrical.

  5. High Velocity Linear Induction Launcher with Exit-Edge Compensation for Testing of Aerospace Components

    NASA Technical Reports Server (NTRS)

    Kuznetsov, Stephen; Marriott, Darin

    2008-01-01

    Advances in ultra high speed linear induction electromagnetic launchers over the past decade have focused on magnetic compensation of the exit and entry-edge transient flux wave to produce efficient and compact linear electric machinery. The paper discusses two approaches to edge compensation in long-stator induction catapults with typical end speeds of 150 to 1,500 m/s. In classical linear induction machines, the exit-edge effect is manifest as two auxiliary traveling waves that produce a magnetic drag on the projectile and a loss of magnetic flux over the main surface of the machine. In the new design for the Stator Compensated Induction Machine (SCIM) high velocity launcher, the exit-edge effect is nulled by a dual wavelength machine or alternately the airgap flux is peaked at a location prior to the exit edge. A four (4) stage LIM catapult is presently being constructed for 180 m/s end speed operation using double-sided longitudinal flux machines. Advanced exit and entry edge compensation is being used to maximize system efficiency, and minimize stray heating of the reaction armature. Each stage will output approximately 60 kN of force and produce over 500 G s of acceleration on the armature. The advantage of this design is there is no ablation to the projectile and no sliding contacts, allowing repeated firing of the launcher without maintenance of any sort. The paper shows results of a parametric study for 500 m/s and 1,500 m/s linear induction launchers incorporating two of the latest compensation techniques for an air-core stator primary and an iron-core primary winding. Typical thrust densities for these machines are in the range of 150 kN/sq.m. to 225 kN/sq.m. and these compete favorably with permanent magnet linear synchronous machines. The operational advantages of the high speed SCIM launcher are shown by eliminating the need for pole-angle position sensors as would be required by synchronous systems. The stator power factor is also improved.

  6. Intended rather than actual movement velocity determines the latency of anticipatory postural adjustments.

    PubMed

    Esposti, Roberto; Bruttini, Carlo; Bolzoni, Francesco; Cavallari, Paolo

    2015-02-01

    The literature reports that anticipatory postural adjustments (APAs) are programmed according to movement velocity. However, the linkage between APAs and velocity has been highlighted within single subjects who were asked to voluntarily change movement velocity; therefore, till now, it has been impossible to discern whether the key factor determining APA latency was the intended movement velocity or the actual one. Aim of this study was to distinguish between these two factors. We analyzed the APA chain that stabilizes the arm during a brisk index finger flexion in two groups of subjects: (1) 29 who composed our database from previous experiments and were asked to "go-as-fast-as-possible" (go-fast), but actually performed the movement with different speeds (238-1, 180°/s), and (2) ten new subjects who performed the go-fast movement at more than 500°/s and were then asked to go-slow at about 50% of their initial velocity, thus moving at 300-800°/s. No correlation between APA latency and actual movement speed was observed when all subjects had to go-fast (p > 0.50), while delayed APAs were found in the ten new subjects when they had to go-slow (p < 0.001). Moreover, in the speed range between 300 and 800°/s, the APA latency depended only on movement instruction: subjects going fast showed earlier APAs than those going slow (p < 0.001). These data suggest a stronger role of the intended movement velocity versus the actual one in modifying the timing of postural muscles recruitment with respect to the prime mover. These results also strengthen the idea of a shared postural and voluntary command within the same motor act.

  7. Effect of Diffuser Design, Diffuser-exit Velocity Profile and Fuel Distribution on Altitude Performance of Several Afterburner Configurations

    NASA Technical Reports Server (NTRS)

    Conrad, E William; Schultz, Frederick W; Usow, Karl H

    1953-01-01

    An investigation was conducted in the NACA Lewis altitude wind tunnel to improve the altitude performance and operational characteristics of an afterburner primarily by modifying the diffuser-exit velocity profile by changes in diffuser design and by changing the fuel distribution and the flame holder. Twenty configurations, consisting of combinations of six diffuser geometries, six flame-holder types, and twelve fuel systems, were investigated. Data were obtained over a range of afterburner fuel-air ratios at diffuser-inlet total pressures from 2750 to 620 pounds per square foot. Changes in fuel distribution affected the fuel-air ratio at which peak combustion efficiency occurred as well as the efficiency level. Screeching combustion, which was most prevalent at low altitudes and medium-to-high fuel-air ratios, imposed a restriction on the operable range of a number of configurations.

  8. Performance of an asymmetric short annular diffuser with a nondiverging inner wall using suction. [control of radial profiles of diffuser exit velocity

    NASA Technical Reports Server (NTRS)

    Juhasz, A.

    1974-01-01

    The performance of a short highly asymmetric annular diffuser equipped with wall bleed (suction) capability was evaluated at nominal inlet Mach numbers of 0.188, 0.264, and 0.324 with the inlet pressure and temperature at near ambient values. The diffuser had an area ratio of 2.75 and a length- to inlet-height ratio of 1.6. Results show that the radial profiles of diffuser exit velocity could be controlled from a severely hub peaked to a slightly tip biased form by selective use of bleed. At the same time, other performance parameters were also improved. These results indicate the possible application of the diffuser bleed technique to control flow profiles to gas turbine combustors.

  9. Rotor with Flattened Exit Pressure Profile

    NASA Technical Reports Server (NTRS)

    Baltas, Constantine (Inventor); Prasad, Dilip (Inventor); Gallagher, Edward J. (Inventor)

    2015-01-01

    A rotor blade comprises an airfoil extending radially from a root section to a tip section and axially from a leading edge to a trailing edge, the leading and trailing edges defining a curvature therebetween. The curvature determines a relative exit angle at a relative span height between the root section and the tip section, based on an incident flow velocity at the leading edge of the airfoil and a rotational velocity at the relative span height. In operation of the rotor blade, the relative exit angle determines a substantially flat exit pressure ratio profile for relative span heights from 75% to 95%, wherein the exit pressure ratio profile is constant within a tolerance of 10% of a maximum value of the exit pressure ratio profile.

  10. Effect of exit locations on ants escaping a two-exit room stressed with repellent

    NASA Astrophysics Data System (ADS)

    Wang, Shujie; Cao, Shuchao; Wang, Qiao; Lian, Liping; Song, Weiguo

    2016-09-01

    In order to investigate the effect of the distance between two exits on ant evacuation efficiency and the behavior of ants escaping from a two-exit room, we conducted ant egress experiments using Camponotus japonicus in multiple situations. We found that the ants demonstrated the phenomenon of "symmetry breaking" in this stress situation. It was also shown that different locations for the exits obviously affected the ants' egress efficiency by measuring the time intervals between individual egress and flow rate in eight repeated experiments, each of which contained five different distance between the two exits. In addition, it is demonstrated that there are differences between the predictions of Social Force Model of pedestrians and the behaviors of ants in stress conditions through comparing some important behavioral features, including position, trajectory, velocity, and density map.

  11. Think Exit at Entry

    ERIC Educational Resources Information Center

    O'Rourke, Tom; Satterfield, Coy E.

    2005-01-01

    This paper describes the "Think Exit at Entry" program that has become the guiding principle for the Georgia Department of Juvenile Justice (DJJ). The Georgia DJJ believes that the transition process begins the day the youth enters the system and continues well after release from the institution. Literature points the need for transition planning…

  12. Bed exit alarms.

    PubMed

    2004-09-01

    Bed-exit alarms alert caregivers that a patient who should not get out of bed unassisted is doing so. These alarms can help reduce the likelihood of falls and can promote speedy assistance to patients who have already fallen. But as we described in our May 2004 Guidance Article on bed-exit alarms, they don't themselves prevent falls. They are only effective if used as part of an overall fall-prevention program and with a clear understanding of their limitations. This Evaluation examines the effectiveness of 16 bed-exit alarms from seven suppliers. Our ratings focus primarily on each product's reliability in detecting bed-exit events and alerting caregivers, its ability to minimize nuisance alarms (alarms that sound even though the patient isn't leaving the bed or that sound while a caregiver is helping the patient to leave the bed), and its resistance to deliberate or inadvertent tampering. Twelve of the products use pressure-sensor-activated alarms (mainly sensor pads placed on or under the mattress); three use a cord that can attach to the patient's garment, alarming if the cord is pulled loose from the control unit; and one is a position-sensitive alarm attached to a leg cuff. All the products reliably detect attempted or successful bed exits. But they vary greatly in how effectively they alert staff, minimize nuisance alarms, and resist tampering. Ease of use and battery performance also vary for many units. Of the pressure-sensor units, three are rated Preferred. Those units meet most of our criteria and have no significant disadvantages. Five of the other pressure-sensor products are Acceptable, and the remaining four are Not Recommended. All three cord-activated alarms are rated Acceptable, as is the patient-worn alarm.

  13. Exit from Synchrony in Joint Improvised Motion

    PubMed Central

    Dahan, Assi; Noy, Lior; Hart, Yuval; Mayo, Avi; Alon, Uri

    2016-01-01

    Motion synchrony correlates with effective and well-rated human interaction. However, people do not remain locked in synchrony; Instead, they repeatedly enter and exit synchrony. In many important interactions, such as therapy, marriage and parent-infant communication, it is the ability to exit and then re-enter synchrony that is thought to build strong relationship. The phenomenon of entry into zero-phase synchrony is well-studied experimentally and in terms of mathematical modeling. In contrast, exit-from-synchrony is under-studied. Here, we focus on human motion coordination, and examine the exit-from-synchrony phenomenon using experimental data from the mirror game paradigm, in which people perform joint improvised motion, and from human tracking of computer-generated stimuli. We present a mathematical mechanism that captures aspects of exit-from-synchrony in human motion. The mechanism adds a random motion component when the accumulated velocity error between the players is small. We introduce this mechanism to several models for human coordinated motion, including the widely studied HKB model, and the predictor-corrector model of Noy, Dekel and Alon. In all models, the new mechanism produces realistic simulated behavior when compared to experimental data from the mirror game and from tracking of computer generated stimuli, including repeated entry and exit from zero-phase synchrony that generates a complexity of motion similar to that of human players. We hope that these results can inform future research on exit-from-synchrony, to better understand the dynamics of coordinated action of people and to enhance human-computer and human-robot interaction. PMID:27711185

  14. Experiment and modeling of exit-selecting behaviors during a building evacuation

    NASA Astrophysics Data System (ADS)

    Fang, Zhiming; Song, Weiguo; Zhang, Jun; Wu, Hao

    2010-02-01

    The evacuation process in a teaching building with two neighboring exits is investigated by means of experiment and modeling. The basic parameters such as flow, density and velocity of pedestrians in the exit area are measured. The exit-selecting phenomenon in the experiment is analyzed, and it is found that pedestrians prefer selecting the closer exit even though the other exit is only a little far. In order to understand the phenomenon, we reproduce the experiment process with a modified biased random walk model, in which the preference of closer exit is achieved using the drift direction and the drift force. Our simulation results afford a calibrated value of the drift force, especially when it is 0.56, there is good agreement between the simulation results and the experimental results on the number of pedestrians selecting the closer exit, the average velocity through the exits, the cumulative distribution of the instantaneous velocity and the fundamental diagram of the flow through exits. According to the further simulation results, it is found that pedestrians tend to select the exit with shorter distance to them, especially when the people density is small or medium. But if the density is large enough, the flow rates of the two exits will become comparable because of the detour behaviors. It reflects the fact that a crowd of people may not be rational to optimize the usage of multi-exits, especially in an emergency.

  15. Exiting prostitution: an integrated model.

    PubMed

    Baker, Lynda M; Dalla, Rochelle L; Williamson, Celia

    2010-05-01

    Exiting street-level prostitution is a complex, convoluted process. Few studies have described this process within any formal conceptual framework. This article reviews two general models and two prostitution-specific models and their applicability to the exiting process. Barriers encountered as women attempt to leave the streets are identified. Based on the four models, the barriers, the prostitution literature, and the authors' experience with prostituted women, a new integrated six-stage model that is comprehensive in scope and sensitive to women's attempts to exit prostitution is offered as a foundation for continued research on the process of women leaving the streets.

  16. 14 CFR 23.807 - Emergency exits.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... with canopies, at least one emergency exit on the opposite side of the cabin from the main door... persons using that exit. (b) Type and operation. Emergency exits must be movable windows, panels,...

  17. 14 CFR 23.807 - Emergency exits.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... with canopies, at least one emergency exit on the opposite side of the cabin from the main door... persons using that exit. (b) Type and operation. Emergency exits must be movable windows, panels,...

  18. 14 CFR 23.807 - Emergency exits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... with canopies, at least one emergency exit on the opposite side of the cabin from the main door... persons using that exit. (b) Type and operation. Emergency exits must be movable windows, panels,...

  19. Exit Times from Equilateral Triangles

    SciTech Connect

    Alabert, Aureli Farre, Merce Roy, Rahul

    2003-12-15

    In this paper we obtain a closed form expression of the expected exit time of a Brownian motion from equilateral triangles. We consider first the analogous problem for a symmetric random walk on the triangular lattice and show that it is equivalent to the ruin problem of an appropriate three player game. A suitable scaling of this random walk allows us to exhibit explicitly the relation between the respective exit times. This gives us the solution of the related Poisson equation.

  20. Bed-exit alarm effectiveness

    PubMed Central

    Capezuti, Elizabeth; Brush, Barbara L.; Lane, Stephen; Rabinowitz, Hannah U.; Secic, Michelle

    2009-01-01

    This study describes the accuracy of two types of bed-exit alarms to detect bed-exiting body movements: pressure-sensitive and a pressure sensitive combined with infrared beam detectors (dual sensor system). We also evaluated the occurrence of nuisance alarms, or alarms that are activated when a participant does not attempt to get out of bed. Fourteen nursing home residents were directly observed for a total of 256 nights or 1,636.5 hours; an average of 18.3 ± 22.3 (± S.D.) nights/participant for an average of 6.4 ± 1.2 hours/night. After adjusting for body movements via repeated measures, Poisson regression modeling, the least squares adjusted means show a marginally significant difference between the type of alarm groups on the number of true positives (mean/S.E.M. = 0.086/1.617) for pressure-sensitive vs. dual sensor alarm (0.593/1.238; p = 0.0599) indicating that the dual sensor alarm may have a higher number of true positives. While the dual sensor bed-exit alarm was more accurate than the pressure sensitive alarm in identifying bed-exiting body movements and reducing the incidence of false alarms, false alarms were not eliminated altogether. Alarms are not a substitute for staff; adequate staff availability is still necessary when residents need or wish to exit bed. PMID:18508138

  1. Bed-exit alarm effectiveness.

    PubMed

    Capezuti, Elizabeth; Brush, Barbara L; Lane, Stephen; Rabinowitz, Hannah U; Secic, Michelle

    2009-01-01

    This study describes the accuracy of two types of bed-exit alarms to detect bed-exiting body movements: pressure-sensitive and a pressure-sensitive combined with infrared (IR) beam detectors (dual sensor system). We also evaluated the occurrence of nuisance alarms, or alarms that are activated when a participant does not attempt to get out of bed. Fourteen nursing home residents were directly observed for a total of 256 nights or 1636.5h; an average of 18.3+/-22.3 (+/-S.D.) nights/participant for an average of 6.4+/-1.2 h/night. After adjusting for body movements via repeated measures, Poisson regression modeling, the least squares adjusted means (LSM) show a marginally significant difference between the type of alarm groups on the number of true positives (NTP) (mean/S.E.M.=0.086/1.617) for pressure-sensitive versus dual sensor alarm (0.593/1.238; p=0.0599) indicating that the dual sensor alarm may have a higher NTP. While the dual sensor bed-exit alarm was more accurate than the pressure-sensitive alarm in identifying bed-exiting body movements and reducing the incidence of false alarms, false alarms were not eliminated altogether. Alarms are not a substitute for staff; adequate staff availability is still necessary when residents need or wish to exit bed.

  2. 49 CFR 239.107 - Emergency exits.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Emergency exits. 239.107 Section 239.107... exits. For additional requirements related to emergency window exits, see part 223 of this chapter. (a... for scheduled inspection, maintenance, and repair of emergency window and door exits; (2) Test...

  3. Video measurement of the muzzle velocity of a potato gun

    NASA Astrophysics Data System (ADS)

    Jasperson, Christopher; Pollman, Anthony

    2011-09-01

    Using first principles, a theoretical equation for the maximum and actual muzzle velocities for a pneumatic cannon was recently derived. For a fixed barrel length, this equation suggests that the muzzle velocity can be enhanced by maximizing the product of the initial pressure and the volume of the propellant gas and decreasing the projectile mass. The present paper describes the results of experiments conducted to verify the validity of this theoretical equation. A high-speed video camera was used to quantify muzzle velocity for potatoes of varying mass exiting a pneumatic cannon for gauge pressures ranging from 310 to 830 kPa. The experiments verified that a friction modified version of the theoretical equation is qualitatively and quantitatively accurate for potato masses above 100 g.

  4. Investigation of the feasibility of optical diagnostic measurements at the exit of the SSME

    NASA Technical Reports Server (NTRS)

    Shirley, John A.; Boedeker, Laurence R.

    1993-01-01

    Under Contract NAS8-36861 sponsored by NASA Marshall Space Flight Center, the United Technologies Research Center is conducting an investigation of the feasibility of remote optical diagnostics to measure temperature, species concentration and velocity at the exit of the Space Shuttle Main Engine (SSME). This is a two phase study consisting of a conceptual design phase followed by a laboratory experimental investigation. The first task of the conceptual design studies is to screen and evaluate the techniques which can be used for the measurements. The second task is to select the most promising technique or techniques, if as expected, more than one type of measurement must be used to measure all the flow variables of interest. The third task is to examine in detail analytically the capabilities and limitations of the selected technique(s). The results of this study are described in the section of this report entitled Conceptual Design Investigations. The conceptual design studies identified spontaneous Raman scattering and photodissociative flow-tagging for measurements respectively of gas temperature and major species concentration and for velocity. These techniques and others that were considered are described in the section describing the conceptual design. The objective of the second phase of investigations was to investigate experimentally the techniques identified in the first phase. The first task of the experimental feasibility study is to design and assemble laboratory scale experimental apparatus to evaluate the best approaches for SSME exit optical diagnostics for temperature, species concentrations and velocity, as selected in the Phase I conceptual design study. The second task is to evaluate performance, investigate limitations, and establish actual diagnostic capabilities, accuracies and precision for the selected optical systems. The third task is to evaluate design requirements and system trade-offs of conceptual instruments. Spontaneous Raman

  5. 14 CFR 121.585 - Exit seating.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Exit seating. 121.585 Section 121.585..., FLAG, AND SUPPLEMENTAL OPERATIONS Flight Operations § 121.585 Exit seating. (a)(1) Each certificate... passenger exit seating determinations required by this paragraph in a non-discriminatory manner...

  6. 14 CFR 135.129 - Exit seating.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Exit seating. 135.129 Section 135.129....129 Exit seating. (a)(1) Applicability. This section applies to all certificate holders operating... certificate holder shall make the passenger exit seating determinations required by this paragraph in a...

  7. 14 CFR 121.585 - Exit seating.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Exit seating. 121.585 Section 121.585..., FLAG, AND SUPPLEMENTAL OPERATIONS Flight Operations § 121.585 Exit seating. (a)(1) Each certificate... passenger exit seating determinations required by this paragraph in a non-discriminatory manner...

  8. 14 CFR 135.129 - Exit seating.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Exit seating. 135.129 Section 135.129....129 Exit seating. (a)(1) Applicability. This section applies to all certificate holders operating... certificate holder shall make the passenger exit seating determinations required by this paragraph in a...

  9. Exit Exam as Academic Performance Indicator

    ERIC Educational Resources Information Center

    Al Ahmad, Mahmoud; Al Marzouqi, Ali H.; Hussien, Mousa

    2014-01-01

    This paper focuses on the impact of exit exams on different elements of the educational process, namely: curriculum development, students and instructors. A 50-question multiple-choice Exit Exam was prepared by Electrical Engineering (EE) faculty members covering a poll of questions from EE core courses. A copy of the Exit Exam applied during each…

  10. Discrete element crowd model for pedestrian evacuation through an exit

    NASA Astrophysics Data System (ADS)

    Peng, Lin; Jian, Ma; Siuming, Lo

    2016-03-01

    A series of accidents caused by crowds within the last decades evoked a lot of scientific interest in modeling the movement of pedestrian crowds. Based on the discrete element method, a granular dynamic model, in which the human body is simplified as a self-driven sphere, is proposed to simulate the characteristics of crowd flow through an exit. In this model, the repulsive force among people is considered to have an anisotropic feature, and the physical contact force due to body deformation is quantified by the Hertz contact model. The movement of the human body is simulated by applying the second Newton’s law. The crowd flow through an exit at different desired velocities is studied and simulation results indicated that crowd flow exhibits three distinct states, i.e., smooth state, transition state and phase separation state. In the simulation, the clogging phenomenon occurs more easily when the desired velocity is high and the exit may as a result be totally blocked at a desired velocity of 1.6 m/s or above, leading to faster-to-frozen effect. Project supported by the National Natural Science Foundation of China (Grant Nos. 71473207, 51178445, and 71103148), the Research Grant Council, Government of Hong Kong, China (Grant No. CityU119011), and the Fundamental Research Funds for the Central Universities, China (Grant Nos. 2682014CX103 and 2682014RC05).

  11. How External Exit Exams Spur Achievement.

    ERIC Educational Resources Information Center

    Bishop, John H.; Mane, Ferran; Bishop, Michael

    2001-01-01

    Compared with minimum competency tests, curriculum-based external exit exams provide better measures of students' achievement levels. Analysis of Third Mathematics and Science Study data shows that 13 year-olds from exit-exam countries are ahead of nonparticipating countries. Effects on college enrollment, job success, and test scores are…

  12. Topological inflation with graceful exit

    NASA Astrophysics Data System (ADS)

    Marunović, Anja; Prokopec, Tomislav

    2016-04-01

    We investigate a class of models of topological inflation in which a super-Hubble-sized global monopole seeds inflation. These models are attractive since inflation starts from rather generic initial conditions, but their not so attractive feature is that, unless symmetry is again restored, inflation never ends. In this work we show that, in presence of another nonminimally coupled scalar field, that is both quadratically and quartically coupled to the Ricci scalar, inflation naturally ends, representing an elegant solution to the graceful exit problem of topological inflation. While the monopole core grows during inflation, the growth stops after inflation, such that the monopole eventually enters the Hubble radius, and shrinks to its Minkowski space size, rendering it immaterial for the subsequent Universe's dynamics. Furthermore, we find that our model can produce cosmological perturbations that source CMB temperature fluctuations and seed large scale structure statistically consistent (within one standard deviation) with all available data. In particular, for small and (in our convention) negative nonminimal couplings, the scalar spectral index can be as large as ns simeq 0.955, which is about one standard deviation lower than the central value quoted by the most recent Planck Collaboration.

  13. Plume rise from a chimney with an elongated exit cross section

    NASA Astrophysics Data System (ADS)

    Seifert, A.; Shemer, L.

    The effect of using a nozzle with an elongated exit cross section as a passive device for increasing jet penetration into cross flow was studied experimentally in a wind tunnel. It was found that the smoke plume dispersion and jet penetration are governed not only by the ratio of flow velocities in the pipe and in the cross flour, but also by the shape of the exit cross section and its orientation with respect to the cross flow. An elongated exit cross section may be particularly effective whenever only a narrow wedge of wind directions leads to air pollution of populated areas. It was found that when such a nozzle is oriented along the wind direction, the chimney effective height is increased as compared to a circular exit cross section, in spite of the fact that the velocity ratio in our experiments was higher for the circular exit. Possible physical reasons for the advantage of the elongated over the circular section shape at the exit are discussed.

  14. Orbital Transfer Vehicle Engine Technology High Velocity Ratio Diffusing Crossover

    NASA Technical Reports Server (NTRS)

    Lariviere, Brian W.

    1992-01-01

    High speed, high efficiency head rise multistage pumps require continuous passage diffusing crossovers to effectively convey the pumped fluid from the exit of one impeller to the inlet of the next impeller. On Rocketdyne's Orbital Transfer Vehicle (OTV), the MK49-F, a three stage high pressure liquid hydrogen turbopump, utilizes a 6.23 velocity ratio diffusing crossover. This velocity ratio approaches the diffusion limits for stable and efficient flow over the operating conditions required by the OTV system. The design of the high velocity ratio diffusing crossover was based on advanced analytical techniques anchored by previous tests of stationary two-dimensional diffusers with steady flow. To secure the design and the analytical techniques, tests were required with the unsteady whirling characteristics produced by an impeller. A tester was designed and fabricated using a 2.85 times scale model of the MK49-F turbopumps first stage, including the inducer, impeller, and the diffusing crossover. Water and air tests were completed to evaluate the large scale turbulence, non-uniform velocity, and non-steady velocity on the pump and crossover head and efficiency. Suction performance tests from 80 percent to 124 percent of design flow were completed in water to assess these pump characteristics. Pump and diffuser performance from the water and air tests were compared with the actual MK49-F test data in liquid hydrogen.

  15. 10 CFR 431.202 - Definitions concerning illuminated exit signs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... COMMERCIAL AND INDUSTRIAL EQUIPMENT Illuminated Exit Signs § 431.202 Definitions concerning illuminated exit... sign. Illuminated exit sign means a sign that— (1) Is designed to be permanently fixed in place...

  16. 10 CFR 431.202 - Definitions concerning illuminated exit signs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... COMMERCIAL AND INDUSTRIAL EQUIPMENT Illuminated Exit Signs § 431.202 Definitions concerning illuminated exit...) Is designed to be permanently fixed in place to identify an exit; and (2) Consists of an...

  17. 49 CFR 393.62 - Emergency exits for buses.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... straight (parallel to the undisturbed exit surface) motions to operate the exit, no more than 89 Newtons... perpendicular to the undisturbed exit surface, no more than 267 Newtons (60 pounds) shall be required to...

  18. 49 CFR 393.62 - Emergency exits for buses.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... straight (parallel to the undisturbed exit surface) motions to operate the exit, no more than 89 Newtons... perpendicular to the undisturbed exit surface, no more than 267 Newtons (60 pounds) shall be required to...

  19. 14 CFR 23.807 - Emergency exits.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... airplanes with a seating capacity of two or more, excluding airplanes with canopies, at least one emergency... and operation. Emergency exits must be movable windows, panels, canopies, or external doors,...

  20. A Rare Case of an Intact Bone Plug Associated with a Gunshot Exit Wound.

    PubMed

    Bird, Cate E; Fleischman, Julie M

    2015-07-01

    This case study presents an unusual manifestation of gunshot trauma in skeletal tissue from a post-World War II human rights abuse sample uncovered in Vilnius, Lithuania. After briefly reviewing the typical wound appearance of projectile trauma in the cranium, we discuss the presence of an intact bone plug associated with a gunshot exit wound in an individual from the Tuskulenai Case. While this individual demonstrated typical gunshot entry and exit wounds to the cranium consistent with high-velocity trauma, the bone plug indicates that the projectile likely lost much of its kinetic energy while traveling through the cranium resulting in a low-velocity impact at the exit site. This study reviews a similar instance of a bone plug recovered from a bioarcheological sample in Peru and emphasizes the importance of thorough archeological excavations of mass graves.

  1. A Rare Case of an Intact Bone Plug Associated with a Gunshot Exit Wound.

    PubMed

    Bird, Cate E; Fleischman, Julie M

    2015-07-01

    This case study presents an unusual manifestation of gunshot trauma in skeletal tissue from a post-World War II human rights abuse sample uncovered in Vilnius, Lithuania. After briefly reviewing the typical wound appearance of projectile trauma in the cranium, we discuss the presence of an intact bone plug associated with a gunshot exit wound in an individual from the Tuskulenai Case. While this individual demonstrated typical gunshot entry and exit wounds to the cranium consistent with high-velocity trauma, the bone plug indicates that the projectile likely lost much of its kinetic energy while traveling through the cranium resulting in a low-velocity impact at the exit site. This study reviews a similar instance of a bone plug recovered from a bioarcheological sample in Peru and emphasizes the importance of thorough archeological excavations of mass graves. PMID:25832722

  2. Exit channels of autoionization resonances in atoms

    SciTech Connect

    Krause, M.O.

    1985-01-01

    In many-electron atoms with open shells strong autoionization resonances occur when an electron from an inner, weakly bound subshell is excited. Usually, the resonance state lies above several ionization thresholds and, hence, will decay into more than one exit or continuum channel. Several cases are discussed in which the resonance state is induced by synchrotron radiation, and the exit channels are differentiated and characterized by the analysis of the ejected electrons.

  3. Cellular Exit Strategies of Intracellular Bacteria.

    PubMed

    Hybiske, Kevin; Stephens, Richard

    2015-12-01

    The coevolution of intracellular bacteria with their eukaryotic hosts has presented these pathogens with numerous challenges for their evolutionary progress and survival. Chief among these is the ability to exit from host cells, an event that is fundamentally linked to pathogen dissemination and transmission. Recent years have witnessed a major expansion of research in this area, and this chapter summarizes our current understanding of the spectrum of exit strategies that are exploited by intracellular pathogens. Clear themes regarding the mechanisms of microbial exit have emerged and are most easily conceptualized as (i) lysis of the host cell, (ii) nonlytic exit of free bacteria, and (iii) release of microorganisms into membrane-encased compartments. The adaptation of particular exit strategies is closely linked with additional themes in microbial pathogenesis, including host cell death, manipulation of host signaling pathways, and coincident activation of proinflammatory responses. This chapter will explore the molecular determinants used by intracellular pathogens to promote host cell escape and the infectious advantages each exit pathway may confer, and it will provide an evolutionary framework for the adaptation of these mechanisms. PMID:27337274

  4. New approach of a traditional analysis for predicting near-exit jet liquid instabilities

    NASA Astrophysics Data System (ADS)

    Jaramillo, Guillermo; Collicott, Steven

    2015-11-01

    Traditional linear instability theory for round liquid jets requires an exit-plane velocity profile be assumed so as to derive the characteristic growth rates and wavelengths of instabilities. This requires solving an eigenvalue problem for the Rayleigh Equation. In this new approach, a hyperbolic tangent velocity profile is assumed at the exit-plane of a round jet and a comparison is made with a hyperbolic secant profile. Temporal and Spatial Stability Analysis (TSA and SSA respectively) are the employed analytical tools to compare results of predicted most-unstable wavelengths from the given analytical velocity profiles and from previous experimental work. The local relevance of the velocity profile in the near-exit region of a liquid jet and the validity of an inviscid formulation through the Rayleigh equation are discussed as well. A comparison of numerical accuracy is made between two different mathematical approaches for the hyperbolic tangent profile with and without the Ricatti transformation. Reynolds number based on the momentum thickness of the boundary layer at the exit plane non-dimensionalizes the problem and, the Re range, based on measurements by Portillo in 2011, is 185 to 600. Wavelength measurements are taken from Portillo's experiment. School of Mechanical Engineering at Universidad del Valle, supported by a grant from Fulbright and Colciencias. Ph.D. student at the School of Aeronautics and Astronautics Purdue University.

  5. The effect of the exit condition on the performance of intube condensers

    SciTech Connect

    Rabas, T.J.; Arman, B.

    1995-07-01

    Data collected from the open literature plus some new, unpublished data will be used to show that the exit condition can change the flow regimes, introduce certain types of instabilities, and alter flooding velocities with intube condensation. The major orientations will be considered: horizontal, vertical with vapor downflow, and vertical with vapor upflow (refluxing).

  6. Form and Actuality

    NASA Astrophysics Data System (ADS)

    Bitbol, Michel

    A basic choice underlies physics. It consists of banishing actual situations from theoretical descriptions, in order to reach a universal formal construct. Actualities are then thought of as mere local appearances of a transcendent reality supposedly described by the formal construct. Despite its impressive success, this method has left major loopholes in the foundations of science. In this paper, I document two of these loopholes. One is the problem of time asymmetry in statistical thermodynamics, and the other is the measurement problem of quantum mechanics. Then, adopting a broader philosophical standpoint, I try to turn the whole picture upside down. Here, full priority is given to actuality (construed as a mode of the immanent reality self-reflectively being itself) over formal constructs. The characteristic aporias of this variety of "Copernican revolution" are discussed.

  7. Exit Strategies: How Low-Performing High Schools Respond to High School Exit Examination Requirements

    ERIC Educational Resources Information Center

    Holme, Jennifer Jellison

    2013-01-01

    Background: Over the past several decades, a significant number of states have either adopted or increased high school exit examination requirements. Although these policies are intended to generate improvement in schools, little is known about how high schools are responding to exit testing pressures. Purpose: This study examined how five…

  8. An Entrance to Exit Polling: Strategies for Using Exit Polls as Experiential Learning Projects

    ERIC Educational Resources Information Center

    Berry, Michael J.; Robinson, Tony

    2012-01-01

    Engaging students in the design, administration, and postelection analysis of an exit poll can be an excellent experiential learning activity. Lelieveldt and Rossen (2009) argue that exit polls are a "perfect teaching tool" because they provide students with a cooperative (rather than competitive) learning experience; help students better connect…

  9. 49 CFR 238.113 - Emergency window exits.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Emergency window exits. 238.113 Section 238.113... § 238.113 Emergency window exits. (a) Number and location. Except as provided in paragraph (a)(3) of... window exits. At least one emergency window exit shall be located in each side of each end (half) of...

  10. 14 CFR 29.805 - Flight crew emergency exits.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Flight crew emergency exits. 29.805 Section... Accommodations § 29.805 Flight crew emergency exits. (a) For rotorcraft with passenger emergency exits that are not convenient to the flight crew, there must be flight crew emergency exits, on both sides of...

  11. 14 CFR 27.805 - Flight crew emergency exits.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Flight crew emergency exits. 27.805 Section... § 27.805 Flight crew emergency exits. (a) For rotorcraft with passenger emergency exits that are not convenient to the flight crew, there must be flight crew emergency exits, on both sides of the rotorcraft...

  12. 12 CFR 611.1250 - Preliminary exit fee estimate.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Preliminary exit fee estimate. 611.1250 Section... System Institution Status § 611.1250 Preliminary exit fee estimate. (a) Preliminary exit fee estimate—terminating association. You must provide a preliminary exit fee estimate to us when you submit the plan...

  13. Jet Exit Rig Six Component Force Balance

    NASA Technical Reports Server (NTRS)

    Castner, Raymond; Wolter, John; Woike, Mark; Booth, Dennis

    2012-01-01

    A new six axis air balance was delivered to the NASA Glenn Research Center. This air balance has an axial force capability of 800 pounds, primary airflow of 10 pounds per second, and a secondary airflow of 3 pounds per second. Its primary use was for the NASA Glenn Jet Exit Rig, a wind tunnel model used to test both low-speed, and high-speed nozzle concepts in a wind tunnel. This report outlines the installation of the balance in the Jet Exit Rig, and the results from an ASME calibration nozzle with an exit area of 8 square-inches. The results demonstrated the stability of the force balance for axial measurements and the repeatability of measurements better than 0.20 percent.

  14. Discrimination and Exiting Homelessness among Homeless Adolescents

    PubMed Central

    Milburn, Norweeta G.; Ayala, George; Rice, Eric; Batterham, Philip; Rotheram-Borus, Mary Jane

    2008-01-01

    This paper examines how newly homeless adolescents’ discrimination experiences were associated with exiting homelessness after six months. A sample of 262 homeless adolescents, aged 12 to 20 years, were recruited and followed longitudinally (six-month retention rate = 88%). Discrimination was related to being gay, lesbian, or bisexual (LGB). Discrimination from family was related to exiting homelessness. Other than those who were LGB, adolescents who reported discrimination from their families were more likely to exit homelessness than adolescents who did not report such discrimination. Suggestions for future research include focusing on the experiences of LGB homeless adolescents, the role of families in the lives of homeless adolescents, and other aspects of discrimination, including salience, frequency, intensity, and duration. PMID:17087527

  15. CHARACTERIZATION OF AIRFLOWS NEAR THE EXIT OF HVAC REGISTERS USING LASER DOPPLER VELOCIMETRY (LDV).

    SciTech Connect

    TUTU,N.K.; KRISHNA,C.R.; ANDREWS,J.W.; BUTCHER,T.A.

    2003-03-13

    A facility to characterize the airflow at the exit of HVAC registers was designed and fabricated. The objective of this work is to obtain velocity and turbulence data at the exit of registers, which can then be used as an input boundary condition in a modern Computational Fluid Dynamics (CFD) code to predict the velocity and temperature distribution in an enclosure, and also the register performance parameters such as throw. During the course of this work, two commonly used registers were tested. Both registers were 8 inch x 4 inch sidewall registers. Laser Doppler Velocimetry was used to measure the axial and vertical components of the velocity vector at various locations across the face of the registers. For the two cases of registers studied here, the results suggest that the velocity field at the very exit of each of these registers scales with the flow rate through the registers. This means that, in the mode of operation in which the supply fan (of an HVAC system) has a ''High'' and ''Low'' setting, similar velocity scaling would result for the type of registers tested here.

  16. Doppler radar velocity measurements for wound ballistics experiments.

    PubMed

    Knudsen, P J; Svender, J

    1994-01-01

    Bullet velocity is a basic parameter in wound ballistics studies. It is usually measured electronically by means of a variety of solid or photoelectric barriers connected to equipment measuring the time elapsing between impulses, enabling the velocity to be calculated. With the advent of Doppler radar velocity measurement of large calibre artillery shells, the use of this equipment for wound ballistics experiments was investigated. Anaesthetized pigs were shot at a range of 9-10 metres and the velocities measured by Doppler radar and photocells were compared. A very good correspondence between the measured entry and exit velocities in low and medium velocity bullets was found, i.e. an average deviation of less than 1% (range 0-2%) between the two types of equipment. In high velocity bullets measurement of entry velocities was just as good, but in both methods measurement of the exit velocity was complicated by the cluttering of signals by fragments of tissue released from the exit wound and the deflection of the bullet, Doppler radar offers important benefits - simple set up, minimal risk of damage of equipment by stray bullets and very good accuracy - and may replace photocells and similar equipment in studies involving low and medium velocity bullets. Measurement of the exit velocity of high velocity bullets is unsatisfactory in both methods, and it is necessary to improve the Doppler radar method in order to measure that as well.

  17. 14 CFR 121.585 - Exit seating.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the seatbacks to the next row objects the size and weight of over-wing window exit doors; (v) To... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS... holder shall determine, to the extent necessary to perform the applicable functions of paragraph (d)...

  18. 14 CFR 135.129 - Exit seating.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the size and weight of over-wing window exit doors; (v) To remove obstructions of size and weight... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS... commuter operations with aircraft having 9 or fewer passenger seats. (2) Duty to make determination...

  19. 30 CFR 56.4530 - Exits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Exits. 56.4530 Section 56.4530 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Fire Prevention and Control Installation/construction/maintenance § 56.4530...

  20. 14 CFR 121.585 - Exit seating.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... section and related to emergency evacuation provided by the certificate holder in printed or graphic form... include on passenger information cards, presented in the language in which briefings and oral commands are... passenger information cards, at each exit seat— (1) In the primary language in which emergency commands...

  1. 14 CFR 121.585 - Exit seating.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... section and related to emergency evacuation provided by the certificate holder in printed or graphic form... include on passenger information cards, presented in the language in which briefings and oral commands are... passenger information cards, at each exit seat— (1) In the primary language in which emergency commands...

  2. Epigenetics as a First Exit Problem

    NASA Astrophysics Data System (ADS)

    Aurell, E.; Sneppen, K.

    2002-01-01

    We develop a framework to discuss the stability of epigenetic states as first exit problems in dynamical systems with noise. We consider in particular the stability of the lysogenic state of the λ prophage. The formalism defines a quantitative measure of robustness of inherited states.

  3. 14 CFR 23.807 - Emergency exits.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., the following requirements apply: (1) In addition to the passenger entry door— (i) For an airplane... section, are required with one on the same side as the passenger entry door and two on the side opposite... emergency exit on the side of the cabin opposite the passenger entry door, provided that— (i) For...

  4. USEPA EXAMPLE EXIT LEVEL ANALYSIS RESULTS

    EPA Science Inventory

    Developed by NERL/ERD for the Office of Solid Waste, the enclosed product provides an example uncertainty analysis (UA) and initial process-based sensitivity analysis (SA) of hazardous waste "exit" concentrations for 7 chemicals and metals using the 3MRA Version 1.0 Modeling Syst...

  5. 49 CFR 239.107 - Emergency exits.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... operating properly; and (3) Repair each inoperative emergency window and door exit on a car before returning... a terminal at the system headquarters and at each division headquarters; (3) Each such terminal has... machine or a printer connected to the computer to retrieve and produce information in a usable format...

  6. Learner Washback Variability in Standardized Exit Tests

    ERIC Educational Resources Information Center

    Pan, Yi-Ching

    2014-01-01

    In much of the world, the issue of accountability and measurement of educational outcomes is highly controversial. Exit testing is part of the movement to ascertain what students have learned and hold institutions and teachers to account. However, compared to the large number of teacher washback studies, learner washback research is lacking…

  7. Scholars Probe Diverse Effects of Exit Exams

    ERIC Educational Resources Information Center

    Viadero, Debra

    2009-01-01

    The author reports on a study released in April 2009 that suggests that California's high school exit exams are affecting some student demographic groups more than others. The California study, which was released by the Institute for Research on Education Policy and Practice at Stanford University, is the latest in a small spate of studies…

  8. Exit blade geometry and part-load performance of small axial flow propeller turbines: An experimental investigation

    SciTech Connect

    Singh, Punit; Nestmann, Franz

    2010-09-15

    A detailed experimental investigation of the effects of exit blade geometry on the part-load performance of low-head, axial flow propeller turbines is presented. Even as these turbines find important applications in small-scale energy generation using micro-hydro, the relationship between the layout of blade profile, geometry and turbine performance continues to be poorly characterized. The experimental results presented here help understand the relationship between exit tip angle, discharge through the turbine, shaft power, and efficiency. The modification was implemented on two different propeller runners and it was found that the power and efficiency gains from decreasing the exit tip angle could be explained by a theoretical model presented here based on classical theory of turbomachines. In particular, the focus is on the behaviour of internal parameters like the runner loss coefficient, relative flow angle at exit, mean axial flow velocity and net tangential flow velocity. The study concluded that the effects of exit tip modification were significant. The introspective discussion on the theoretical model's limitation and test facility suggests wider and continued experimentation pertaining to the internal parameters like inlet vortex profile and exit swirl profile. It also recommends thorough validation of the model and its improvement so that it can be made capable for accurate characterization of blade geometric effects. (author)

  9. Low-noise fan exit guide vanes

    NASA Technical Reports Server (NTRS)

    Jones, Michael G. (Inventor); Parrott, Tony L. (Inventor); Heidelberg, Laurence J. (Inventor); Envia, Edmane (Inventor)

    2008-01-01

    Low-noise fan exit guide vanes are disclosed. According to the present invention a fan exit guide vane has an outer shell substantially shaped as an airfoil and defining an interior cavity. A porous portion of the outer shell allows communication between the fluctuations in the air passing over the guide vane and the interior cavity. At least one acoustically resonant chamber is located within the interior cavity. The resonant chamber is in communication with the porous portion of the outer perimeter. The resonant chamber is configured to reduce the noise generated at a predetermined frequency. In various preferred embodiments, there is a plurality of acoustically resonant chambers located within the interior cavity. The resonant chambers can be separated by one or more partitions within the interior cavity. In these embodiments, the resonant chambers can be configured to reduce the noise generated over a range of predetermined frequencies.

  10. Preventing 'exit block' in emergency departments.

    PubMed

    Cairney, Kevin; Clancy, Elaine

    2014-11-01

    Overcrowding due to poor patient flow increases risk for more than 500,000 patients a year ( College of Emergency Medicine (CEM) 2014 ) and is linked to increased mortality ( Geelhoed and de Klerk 2012 ). CEM ( 2014 ) has called for urgent action to address 'exit block' in UK emergency departments (EDs). In October last year, Croydon Health Services NHS Trust designed and implemented a site practitioner early warning system (SPEWS) to alert staff to capacity and flow pressures in the ED, and to initiate escalation to a nurse-led, protocol-driven response. Under pressurised and time-critical conditions, SPEWS ensures rigour and conformity in exchanges between clinical emergency care staff and managers. The result is closer collaboration between clinicians and managers, optimised patient flow and mitigated risk from exit block. PMID:25369968

  11. Mathematical design of a highway exit curve

    NASA Astrophysics Data System (ADS)

    Pakdemirli, Mehmet

    2016-01-01

    A highway exit curve is designed under the assumption that the tangential and normal components of the acceleration of the vehicle remain constant throughout the path. Using fundamental principles of physics and calculus, the differential equation determining the curve function is derived. The equation and initial conditions are cast into a dimensionless form first for universality of the results. It is found that the curves are effected by only one dimensionless parameter which is the ratio of the tangential acceleration to the normal acceleration. For no tangential acceleration, the equation can be solved analytically yielding a circular arc solution as expected. For nonzero tangential acceleration, the function is complicated and no closed-form solutions exist for the differential equation. The equation is solved numerically for various acceleration ratios. Discussions for applications to highway exits are given.

  12. GCFR plenum shield design: exit shield experiment

    SciTech Connect

    Muckenthaler, F.J.; Hull, J.L.; Manning, J.J.

    1981-05-01

    This report describes the integral flux, energy spectra, and dose rate measurements made for the Exit Shield Experiment at the Oak Ridge National Laboratory Tower Shielding Facility as part of the Gas Cooled Fast Breeder Reactor program. The source was the same mockup of fuel pins used in the previous Grid Plate Shield Experiment. Two mockups of the upper axial shield were studied: one with seven subassemblies prototypic of that portion of the Exit Shield without a control rod, and another that was representative of the shield region with a control rod. The experiment was performed to provide verification of: the shield design methods, the shield effectiveness of a prototypic mockup, the analytical ability to calculate streaming effects in the presence of a control rod, and the source term bias factors for the upper plenum.

  13. 14 CFR 25.811 - Emergency exit marking.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... must be conspicuously marked. (b) The identity and location of each passenger emergency exit must be..., Type C or Type I passenger emergency exit operating handle must— (i) Be self-illuminated with...

  14. 14 CFR 25.811 - Emergency exit marking.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... must be conspicuously marked. (b) The identity and location of each passenger emergency exit must be..., Type C or Type I passenger emergency exit operating handle must— (i) Be self-illuminated with...

  15. 14 CFR 25.811 - Emergency exit marking.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... must be conspicuously marked. (b) The identity and location of each passenger emergency exit must be..., Type C or Type I passenger emergency exit operating handle must— (i) Be self-illuminated with...

  16. 14 CFR 25.811 - Emergency exit marking.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... must be conspicuously marked. (b) The identity and location of each passenger emergency exit must be..., Type C or Type I passenger emergency exit operating handle must— (i) Be self-illuminated with...

  17. The effect of exit conditions on the development of an axisymmetric turbulent free jet

    NASA Technical Reports Server (NTRS)

    Kleis, S. J.; Foss, J. F.

    1974-01-01

    The mean flow in the near field of a submerged axisymmetric jet emitting from a plane wall is presented. An experimental configuration to provide a nearly uniform mean velocity profile with a core of homogeneous turbulence of variable intensity and scale was developed. Eight cases with intensity values of 0.004 less than or equal to U prime less than or equal to 0.035 and integral scales up to l sub x/R = 0.28 were investigated using conditional sampling techniques. It was found that the jet exhibits an increasing momentum flux in the near field. Contrary to expectation and the accepted assumption of ambient static pressure in a turbulent jet, results seem to be conclusive and borne out by comparison with published data. Both integral measures, mass and momentum flux ratios, are insensitive to exit turbulence variations, but, the detailed structure (including centerline velocity) variations with exit conditions are systematic and explainable.

  18. 8 CFR 215.9 - Temporary Worker Visa Exit Program.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Temporary Worker Visa Exit Program. 215.9... ALIENS DEPARTING FROM THE UNITED STATES § 215.9 Temporary Worker Visa Exit Program. An alien admitted on certain temporary worker visas at a port of entry participating in the Temporary Worker Visa Exit...

  19. 10 CFR 429.48 - Illuminated exit signs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 3 2012-01-01 2012-01-01 false Illuminated exit signs. 429.48 Section 429.48 Energy... COMMERCIAL AND INDUSTRIAL EQUIPMENT Certification § 429.48 Illuminated exit signs. (a) Sampling plan for selection of units for testing. (1) The requirements of § 429.11 are applicable to illuminated exit...

  20. 10 CFR 429.48 - Illuminated exit signs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 3 2014-01-01 2014-01-01 false Illuminated exit signs. 429.48 Section 429.48 Energy... COMMERCIAL AND INDUSTRIAL EQUIPMENT Certification § 429.48 Illuminated exit signs. (a) Sampling plan for selection of units for testing. (1) The requirements of § 429.11 are applicable to illuminated exit...

  1. 10 CFR 429.48 - Illuminated exit signs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 3 2013-01-01 2013-01-01 false Illuminated exit signs. 429.48 Section 429.48 Energy... COMMERCIAL AND INDUSTRIAL EQUIPMENT Certification § 429.48 Illuminated exit signs. (a) Sampling plan for selection of units for testing. (1) The requirements of § 429.11 are applicable to illuminated exit...

  2. EOS Terra Terra Constellation Exit/Future Maneuver Plans Update

    NASA Technical Reports Server (NTRS)

    Mantziaras, Dimitrios

    2016-01-01

    This EOS Terra Constellation Exit/Future Maneuver Plans Update presentation will discuss brief history of Terra EOM work; lifetime fuel estimates; baseline vs. proposed plan origin; resultant exit orbit; baseline vs. proposed exit plan; long term orbit altitude; revised lifetime proposal and fallback options.

  3. TomoTherapy MLC verification using exit detector data

    SciTech Connect

    Chen Quan; Westerly, David; Fang Zhenyu; Sheng, Ke; Chen Yu

    2012-01-15

    Purpose: Treatment delivery verification (DV) is important in the field of intensity modulated radiation therapy (IMRT). While IMRT and image guided radiation therapy (IGRT), allow us to create more conformal plans and enables the use of tighter margins, an erroneously executed plan can have detrimental effects on the treatment outcome. The purpose of this study is to develop a DV technique to verify TomoTherapy's multileaf collimator (MLC) using the onboard mega-voltage CT detectors. Methods: The proposed DV method uses temporal changes in the MVCT detector signal to predict actual leaf open times delivered on the treatment machine. Penumbra and scattered radiation effects may produce confounding results when determining leaf open times from the raw detector data. To reduce the impact of the effects, an iterative, Richardson-Lucy (R-L) deconvolution algorithm is applied. Optical sensors installed on each MLC leaf are used to verify the accuracy of the DV technique. The robustness of the DV technique is examined by introducing different attenuation materials in the beam. Additionally, the DV technique has been used to investigate several clinical plans which failed to pass delivery quality assurance (DQA) and was successful in identifying MLC timing discrepancies as the root cause. Results: The leaf open time extracted from the exit detector showed good agreement with the optical sensors under a variety of conditions. Detector-measured leaf open times agreed with optical sensor data to within 0.2 ms, and 99% of the results agreed within 8.5 ms. These results changed little when attenuation was added in the beam. For the clinical plans failing DQA, the dose calculated from reconstructed leaf open times played an instrumental role in discovering the root-cause of the problem. Throughout the retrospective study, it is found that the reconstructed dose always agrees with measured doses to within 1%. Conclusions: The exit detectors in the TomoTherapy treatment systems

  4. Thermoacoustic limit cycles in a premixed laboratory combustor with open and choked exits

    SciTech Connect

    Hield, Peter A.; Brear, Michael J.; Jin, Seong Ho

    2009-09-15

    This paper presents an experimental and theoretical investigation of the response of a turbulent premixed flame during thermoacoustic limit cycle in a simple, laboratory combustor. The flame dynamics are examined using high-speed pressure transducers and CH* chemiluminescence. The so-called 'interaction index' and time delay between the acoustic velocity fluctuations at the flame holder and the flame's overall heat release fluctuations are then determined. A wide range of operating conditions, traversing the combustor's flammability limits in Mach number and equivalence ratio, are studied for four different combustor exits, including one where the exit is choked. In all cases the time delay correlates very well with the amplitude of the velocity fluctuations. There is also some correlation between the interaction index and these velocity fluctuations, but this is less clear. These results suggest a novel, nonlinear flame model, derived entirely empirically. An existing low-order thermoacoustic model is then extended to include convection and dispersion of entropy fluctuations downstream of the flame, enabling the effect of the choked nozzle to be examined. The novel nonlinear flame model is integrated into the low-order thermoacoustic model, and used to investigate the experimentally observed thermoacoustic limit cycles. The model correctly simulates the observed switch to a low-frequency, entropically driven instability observed when the combustor exit is choked. (author)

  5. Incomplete shored exit wounds: a report of three cases.

    PubMed

    Druid, H; Ward, M E

    2000-09-01

    Typical and atypical exit wounds are well described in the forensic literature. Included in the descriptions of atypical exit wounds are perforating, "shored" exit wounds, in which the perforation of the skin is associated with an abrasion, whether or not the bullet fully exits the body. The authors describe an atypical, incomplete, shored exit wound in which the skin was abraded by supporting material at the site the bullet was recovered, but there was no associated perforation of the skin. Recognition of this injury pattern can be important in reconstruction of the crime scene in relation to the victim at the time of the shooting. PMID:10990280

  6. Fixed Exit Monochromator with fixed Rotation Axis

    SciTech Connect

    Caliebe, W.A.; Cheung, S.; Lenhard, A.; Siddons, D.P.

    2004-05-12

    A new simple design for a fixed-exit monochromator has been developed. The set-up uses a linear slide to couple the rotation of the crystals to a translation of the second one to compensate for the 2hcos{theta} dependence of the beam-offset in a double crystal monochromator. This set-up requires just one motor for the rotation of the monochromator, and three piezo-actuators to tune the second crystal.The monochromator has been tested for Bragg-angles between 7 deg. and 70 deg.

  7. Tertiary interactions within the ribosomal exit tunnel.

    PubMed

    Kosolapov, Andrey; Deutsch, Carol

    2009-04-01

    Although tertiary folding of whole protein domains is prohibited by the cramped dimensions of the ribosomal tunnel, dynamic tertiary interactions may permit folding of small elementary units within the tunnel. To probe this possibility, we used a beta-hairpin and an alpha-helical hairpin from the cytosolic N terminus of a voltage-gated potassium channel and determined a probability of folding for each at defined locations inside and outside the tunnel. Minimalist tertiary structures can form near the exit port of the tunnel, a region that provides an entropic window for initial exploration of local peptide conformations. Tertiary subdomains of the nascent peptide fold sequentially, but not independently, during translation. These studies offer an approach for diagnosing the molecular basis for folding defects that lead to protein malfunction and provide insight into the role of the ribosome during early potassium channel biogenesis.

  8. Tertiary Interactions within the Ribosomal Exit Tunnel

    PubMed Central

    Kosolapov, Andrey; Deutsch, Carol

    2009-01-01

    Although tertiary folding of whole protein domains is prohibited by the cramped dimensions of the ribosomal tunnel, dynamic tertiary interactions may permit folding of small elementary units within the tunnel. To probe this possibility, we used a β-hairpin as well as an α-helical hairpin from the cytosolic N-terminus of a voltage-gated potassium channel and determined a probability of folding for each at defined locations inside and outside the tunnel. Minimalist tertiary structures can form near the exit port of the tunnel, a region that provides an entropic window for initial exploration of local peptide conformations. Tertiary subdomains of the nascent peptide fold sequentially, but not independently, during translation. These studies offer an approach for diagnosing the molecular basis for folding defects that lead to protein malfunction and provide insight into the role of the ribosome during early potassium channel biogenesis. PMID:19270700

  9. Pulsed laser Rayleigh scattering diagnostic for hydrogen/oxygen rocket exit plane flowfield velocimetry

    NASA Technical Reports Server (NTRS)

    Zupanc, Frank J.

    1993-01-01

    A Doppler-resolved, pulsed laser Rayleigh scattering diagnostic has been developed to obtain local flowfield velocity measurements at the exit plane of a low thrust hydrogen/oxygen rocket engine operating in a high-altitude test facility. Fiberoptic signal collection was employed to obtain the forescatter and backscatter Doppler shifts necessary to resolve the axial and radial velocity components. A radial profile was obtained by traversing the collection probes along the beam path at the nozzle exit. The results are compared with theoretical predictions from a full Navier-Stokes model (RK/RPLUS). Significant discrepancies between the measured and predicted axial velocity profiles are observed, in terms of both magnitude and character. Radial velocity measurements exhibit excellent agreement with predictions near the centerline but show some departure off-axis. The discrepancies between theory and experiment are potentially the result of enhanced mixing between the core and fuel-film region beyond that predicted, and/or flow stratification between the hydrogen and oxygen injected into the central core region.

  10. Exit plane H2O concentration measurements correlated with OH PLIF near-injector mixing measurements for scramjet flows

    NASA Technical Reports Server (NTRS)

    Parker, T. E.; Allen, Mark G.; Foutter, R. R.; Sonnenfroh, D. M.; Rawlins, W. T.

    1992-01-01

    Mixing and combusting high enthalpy flows, similar to those encountered in scramjet engines, were investigated using a shock tunnel to produce the flow in conjunction with non-intrusive optical diagnostics which monitored the performance of two injector configurations. The shock tunnel is configured to produce Mach 3 flow and stagnation enthalpies corresponding to flight equivalent Mach numbers between 7 and 11. A pulsed hydrogen injection capability and interchangeable injector blocks provide a means of examining high speed, high enthalpy reacting flows. Planar laser induced fluorescence (PLIF) of OH molecules in the near injector region produced images which show the combusting and mixing zones for the reacting flow. Line-of-sight exit plane measurement of water concentration and temperature were used to provide a unique method of monitoring exit plane products. These results demonstrated that a velocity matched axial injection system produced a fuel jet that lifted off the floor of the duct. Mixing was observed to increase for this system as a velocity mismatch was introduced. Comparison of exit plane water concentrations for a wall jet injection system and a velocity matched injection system indicated similar mixing performance but an accurate pressure measurement is necessary to further validate the result. In addition, exit plane measurements indicated an approximate steady-state condition was achieved during the 1 to 2 ms test times.

  11. 19 CFR 18.22 - Procedure at port of exit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Procedure at port of exit. 18.22 Section 18.22... to Foreign Countries § 18.22 Procedure at port of exit. (a) If transfer is necessary, the procedure shall be as prescribed in § 18.3(d). (b) Upon the arrival at the port of exit of express shipments...

  12. 19 CFR 18.22 - Procedure at port of exit.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Procedure at port of exit. 18.22 Section 18.22... to Foreign Countries § 18.22 Procedure at port of exit. (a) If transfer is necessary, the procedure shall be as prescribed in § 18.3(d). (b) Upon the arrival at the port of exit of express shipments...

  13. Extrauterine Intrapartum Treatment (EXIT) in bilateral primary fetal hydrothorax.

    PubMed

    Henry, P Y; Aravindan, C S; Sivakumar, K; Krishna, H R

    2009-01-01

    Primary Foetal Hydrothorax (PFHT), is an intrathoracic collection of fluid in the fetus, which may be present on either side or even bilaterally. Advances in foetal diagnostics now allow consideration of the Ex-utero Intrapartum Treatment (EXIT) procedure for PFHT. Ex-utero Intrapartum Treatment (EXIT) allows therapeutic interventions on the neonate while maintaining fetoplacental circulation and thereby maintaining oxygenation. We report two cases of bilateral PFHT managed successfully with EXIT procedure.

  14. Observation of strong reflection of electron waves exiting a ballistic channel at low energy

    NASA Astrophysics Data System (ADS)

    Vaz, Canute I.; Liu, Changze; Campbell, Jason P.; Ryan, Jason T.; Southwick, Richard G., III; Gundlach, David; Oates, Anthony S.; Huang, Ru; Cheung, Kin. P.

    2016-06-01

    Wave scattering by a potential step is a ubiquitous concept. Thus, it is surprising that theoretical treatments of ballistic transport in nanoscale devices, from quantum point contacts to ballistic transistors, assume no reflection even when the potential step is encountered upon exiting the device. Experiments so far seem to support this even if it is not clear why. Here we report clear evidence of coherent reflection when electron wave exits the channel of a nanoscale transistor and when the electron energy is low. The observed behavior is well described by a simple rectangular potential barrier model which the Schrodinger's equation can be solved exactly. We can explain why reflection is not observed in most situations but cannot be ignored in some important situations. Our experiment also represents a direct measurement of electron injection velocity - a critical quantity in nanoscale transistors that is widely considered not measurable.

  15. 46 CFR 153.353 - High velocity vents.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false High velocity vents. 153.353 Section 153.353 Shipping... Systems § 153.353 High velocity vents. The discharge point of a B/3 or 4m venting system must be located..., unimpeded jet; (b) The jet has a minimum exit velocity of 30 m/sec (approx. 98.4 ft/sec); and (c) The...

  16. 46 CFR 153.353 - High velocity vents.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false High velocity vents. 153.353 Section 153.353 Shipping... Systems § 153.353 High velocity vents. The discharge point of a B/3 or 4m venting system must be located..., unimpeded jet; (b) The jet has a minimum exit velocity of 30 m/sec (approx. 98.4 ft/sec); and (c) The...

  17. 46 CFR 153.353 - High velocity vents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false High velocity vents. 153.353 Section 153.353 Shipping... Systems § 153.353 High velocity vents. The discharge point of a B/3 or 4m venting system must be located..., unimpeded jet; (b) The jet has a minimum exit velocity of 30 m/sec (approx. 98.4 ft/sec); and (c) The...

  18. 46 CFR 153.353 - High velocity vents.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false High velocity vents. 153.353 Section 153.353 Shipping... Systems § 153.353 High velocity vents. The discharge point of a B/3 or 4m venting system must be located..., unimpeded jet; (b) The jet has a minimum exit velocity of 30 m/sec (approx. 98.4 ft/sec); and (c) The...

  19. 46 CFR 153.353 - High velocity vents.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false High velocity vents. 153.353 Section 153.353 Shipping... Systems § 153.353 High velocity vents. The discharge point of a B/3 or 4m venting system must be located..., unimpeded jet; (b) The jet has a minimum exit velocity of 30 m/sec (approx. 98.4 ft/sec); and (c) The...

  20. Evaluation of catalytic combustion of actual coal-derived gas

    NASA Astrophysics Data System (ADS)

    Blanton, J. C.; Shisler, R. A.

    1982-02-01

    The combustion characteristics of a Pt-Pl catalytic reactor burning coal-derived, low-Btu gas were investigated. A large matrix of test conditions was explored involving variations in fuel/air inlet temperature and velocity, reactor pressure, and combustor exit temperature. Other data recorded included fuel gas composition, reactor temperatures, and exhaust emissions. Operating experience with the reactor was satisfactory. Combustion efficiencies were quite high (over 95 percent) over most of the operating range. Emissions of NOx were quite high (up to 500 ppm V and greater), owing to the high ammonia content of the fuel gas.

  1. Evaluation of catalytic combustion of actual coal-derived gas

    NASA Technical Reports Server (NTRS)

    Blanton, J. C.; Shisler, R. A.

    1982-01-01

    The combustion characteristics of a Pt-Pl catalytic reactor burning coal-derived, low-Btu gas were investigated. A large matrix of test conditions was explored involving variations in fuel/air inlet temperature and velocity, reactor pressure, and combustor exit temperature. Other data recorded included fuel gas composition, reactor temperatures, and exhaust emissions. Operating experience with the reactor was satisfactory. Combustion efficiencies were quite high (over 95 percent) over most of the operating range. Emissions of NOx were quite high (up to 500 ppm V and greater), owing to the high ammonia content of the fuel gas.

  2. Analysis of heat transfer in a porous cooled wall with variable pressure and temperature along the coolant exit boundary

    NASA Technical Reports Server (NTRS)

    Siegel, R.; Goldstein, M. E.

    1972-01-01

    Fluid from a reservior at constant pressure and temperature is forced through a porous wall of uniform thickness. The boundary through which the fluid exits has specified variations in pressure and temperature along it in one direction so that the flow and heat transfer are two-dimensional. The local fluid and matrix temperatures are assumed to be equal and therefore a single energy equation governs the temperature distribution within the wall. The solution is obtained by transforming this energy equation into potential plane coordinates, which results in a separable equation. A technique yielding an integral equation is used to adapt the general solution so that it satisfies the variable-pressure boundary condition. Analytical expressions are given for the normal exit velocity and heat flux along the exit boundary. Illustrative examples are carried out which indicate to what extent the solution is locally one-dimensional.

  3. Assessing Undergraduate Curriculum Through Student Exit Vectors

    NASA Astrophysics Data System (ADS)

    Keane, C. M.; Gonzales, L.; Martinez, C.

    2008-12-01

    One aspect of assessing the undergraduate curriculum is recognizing that the exit vector of the student is a metric in the absence of a structured assessment program. Detailed knowledge across all geosciences departments regarding the disposition of their recent baccalaureate recipients has been at best inconsistent, and in the case of about half of geoscience programs, non-existent. However, through examining of multiple datasets, a pattern of disposition of geosciences BS recipients emerges, providing a snapshot of the system- wide response to the system-wide "average" program. This pattern can also be juxtaposed against several frameworks of desired skill sets for recent graduates and the employment sectors likely to hire them. The question remains is can one deduce the effectiveness of the undergraduate program in placing graduates in their next step, whether in graduate school or the workplace. Likewise, with an increasing scrutiny on the "value" of an education, is the resulting economic gain sufficient for the student, such that programs will be viewed as sustainable. A factor in answering this question is the importance of the undergraduate program in the ultimate destination of the professional. Clear pathways exist for "optimal" schools for the production of new faculty and new industry professionals, but is it possible to identify those trends further up the educational pipeline? One major mechanism to examine the undergraduate program effectiveness related to exit vectors is to look at hiring trends witnessed related to markedly different program structures, such as those at universities outside of the United States. Rectifying academic programs between the United States and other national systems is often a challenge, but even given the substantial differences between depth of technical knowledge and breadth of education across these programs, in the end, the sum product is often viewed as roughly comparable. This paper will look at end

  4. Towards an Orderly Exit Regime in English Higher Education

    ERIC Educational Resources Information Center

    Fisher, Andrew

    2016-01-01

    In a competitive market, the exit of those suppliers who cannot offer an attractive product at an attractive price is seen as desirable. However, the consequences for consumers when their own supplier leaves the market in an unplanned or disorderly way may be undesirable. Exit regimes exist in regulated markets to ensure that consumers are not…

  5. 12 CFR 611.1255 - Exit fee calculation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Institution Status § 611.1255 Exit fee calculation. (a) Final exit fee calculation—terminating association...) Compute the average daily balances based on financial statements that comply with GAAP. The financial... related to a requirement by the FCA to engage independent experts to conduct assessments, analyses,...

  6. 12 CFR 611.1250 - Preliminary exit fee estimate.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... System Institution Status § 611.1250 Preliminary exit fee estimate. (a) Preliminary exit fee estimate... average daily balances based on financial statements that comply with GAAP. The financial statements, as... engage independent experts to conduct assessments, analyses, or studies, or to request rulings...

  7. 12 CFR 611.1250 - Preliminary exit fee estimate.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 611.1250 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM ORGANIZATION Termination of System Institution Status § 611.1250 Preliminary exit fee estimate. (a) Preliminary exit fee estimate... engage independent experts to conduct assessments, analyses, or studies, or to request rulings...

  8. State High School Exit Exams: A Policy in Transition

    ERIC Educational Resources Information Center

    McIntosh, Shelby

    2012-01-01

    Since 2002, the Center on Education Policy (CEP) at The George Washington University, a national advocate for public education and improving public schools, has been studying state high school exit examinations--tests students must pass to receive a high school diploma. This year marks the 11th year CEP has reported on exit exams in order to help…

  9. 14 CFR 29.807 - Passenger emergency exits.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... a crash landing must be extremely remote. (d) Ditching emergency exits for passengers. If... rotorcraft that have a passenger seating configuration, excluding pilots seats, of nine seats or less, one... exit. (2) For rotorcraft that have a passenger seating configuration, excluding pilots seats, of...

  10. 14 CFR 29.807 - Passenger emergency exits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... a crash landing must be extremely remote. (d) Ditching emergency exits for passengers. If... rotorcraft that have a passenger seating configuration, excluding pilots seats, of nine seats or less, one... exit. (2) For rotorcraft that have a passenger seating configuration, excluding pilots seats, of...

  11. 14 CFR 29.807 - Passenger emergency exits.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... a crash landing must be extremely remote. (d) Ditching emergency exits for passengers. If... rotorcraft that have a passenger seating configuration, excluding pilots seats, of nine seats or less, one... exit. (2) For rotorcraft that have a passenger seating configuration, excluding pilots seats, of...

  12. 14 CFR 29.807 - Passenger emergency exits.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... a crash landing must be extremely remote. (d) Ditching emergency exits for passengers. If... rotorcraft that have a passenger seating configuration, excluding pilots seats, of nine seats or less, one... exit. (2) For rotorcraft that have a passenger seating configuration, excluding pilots seats, of...

  13. 14 CFR 29.807 - Passenger emergency exits.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... a crash landing must be extremely remote. (d) Ditching emergency exits for passengers. If... rotorcraft that have a passenger seating configuration, excluding pilots seats, of nine seats or less, one... exit. (2) For rotorcraft that have a passenger seating configuration, excluding pilots seats, of...

  14. 49 CFR 393.62 - Emergency exits for buses.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... the exit. (e) Emergency exit identification. Each bus and each school bus used in interstate commerce... (including a school bus used in interstate commerce for non-school bus operations) with a GVWR of more than 4... manufacture. (2) Each bus (including a school bus used in interstate commerce for non-school bus...

  15. Exit and Voice: Organizational Loyalty and Dispute Resolution Strategies

    ERIC Educational Resources Information Center

    Hoffmann, Elizabeth A.

    2006-01-01

    This study compares workplace dispute resolution strategies (exit, voice and toleration) in matched pairs of conventional and worker-owned cooperative organizations operating in three industries--coal mining, taxicab driving and organic food distribution. Building on Hirschman's classic exit, voice and loyalty thesis, this research demonstrates…

  16. Jet Nozzle Having Centerbody for Enhanced Exit Area Mixing

    NASA Technical Reports Server (NTRS)

    Seiner, John M. (Inventor); Gilinsky, Mikhail M. (Inventor)

    1999-01-01

    A nozzle arrangement includes a nozzle and a centerbody. The longitudinal axis of the centerbody is coaxially aligned with the nozzle. The centerbody has a free end portion shaped to create vortices in exhaust exiting the exit area. The vortices enhance mixing action in the exhaust and reduce exhaust noise while augmenting thrust.

  17. Exit Surveying of Interns: Demonstrating Impact on Young Professionals

    ERIC Educational Resources Information Center

    Muscio, Cara

    2011-01-01

    Documenting impact is becoming increasingly important as funding becomes tighter for Extension programs. An exit survey for interns conducted via an online survey tool is an opportunity to collect information on knowledge and skill gains, as well as document changes in intentions and attitudes about future career paths. An exit survey conducted…

  18. ETR WASTE GAS EXITED THE ETR COMPLEX FROM THE NORTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ETR WASTE GAS EXITED THE ETR COMPLEX FROM THE NORTH SIDE THROUGH A TUNNEL AND THEN TO A FILTER PIT. TUNNEL EXIT IS UNDER CONSTRUCTION WHILE CONTROL BUILDING IS BEING FORMED BEYOND. CAMERA FACING WEST. INL NEGATIVE NO. 56-1238. Jack L. Anderson, Photographer, 4/17/1956 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  19. Multiple Exit Points in Vocational Education for Students with Disabilities.

    ERIC Educational Resources Information Center

    Florida State Dept. of Education, Tallahassee. Bureau of Education for Exceptional Students.

    This technical assistance paper is designed as a general guide to assist school districts in developing and implementing multiple-exit vocational programs for students with disabilities. The following topics are covered in Part 1: the concept of multiple-exit points (MEPs) and its background, purposes and benefits of MEPs, goals and guiding…

  20. Exiting and Returning to the Parental Home for Boomerang Kids

    PubMed Central

    Sandberg-Thoma, Sara E.; Snyder, Anastasia R.; Jang, Bohyun Joy

    2015-01-01

    Young adults commonly exit from and return to the parental home, yet few studies have examined the motivation behind these exits and returns using a life course framework. Using data from the National Longitudinal Survey of Youth 1997, the authors examined associations between mental health problems and economic characteristics and exits from (n = 8,162), and returns to (n = 6,530), the parental home during the transition to adulthood. The average age of the respondents was 24 years. The authors found evidence that mental health and economic characteristics were related to home leaving and returning. Emotional distress was associated with earlier exits from, and returns to, the parental home; alcohol problems were associated with earlier returns to the parental home. The findings regarding economic resources were unexpectedly mixed. Greater economic resources were linked to delayed exits from, and earlier returns to, the parental home. The implications of these findings for young adults are discussed. PMID:26023244

  1. Multiple program participation and exits from food stamps among elders.

    PubMed

    Issar, Sukriti

    2010-01-01

    This article uses population-level administrative data from Rhode Island's Food Stamp Program to examine exits from the Food Stamp Program by elders. Multivariate event history models estimate the relations of multiple program participation and the timing of eligibility reviews to the probability of exiting food stamps. Results suggest that elders who are age 65 or older and who receive both Supplemental Security Income and food stamps have a higher probability of exiting the Food Stamp Program than do elders who receive only food stamps. The timing of eligibility reviews is also found to be positively associated with the probability of exit from food stamps. This article is argued to extend conceptual models of the determinants of food stamp exits. PMID:20873021

  2. Exit Interview-Consultation for Research Validation and Dissemination

    PubMed Central

    Utley-Smith, Queen; Bailey, Donald; Ammarell, Natalie; Corazzini, Kirsten; Colón-Emeric, Cathleen S.; Lekan-Rutledge, Deborah; Piven, Mary L.; Anderson, Ruth A.

    2006-01-01

    Dissemination of research findings to practice and maintaining rigor and validity in qualitative research is a continuing challenge for nurse researchers. Using three nursing home case studies as examples, we describe how exit interview-consultation was used as: (1) a validation strategy, and; (2) as a rapid research dissemination tool that is particularly useful for nursing systems research. Through an exit interview–consultation method, researchers validated inferences made from qualitative and quantitative data collected in three comprehensive nursing home case studies that examined nursing management practices. This exit interview-consultation strategy extends the traditional member check approach by providing confirmation at the individual and organizational level. We examined how using the exit interview-consultation strategy can potentially assist nursing home organizations to increase their capacity for improving operations. Benefits from research participation are often indirect; this study's results suggest that exit interview-consultation can provide direct and immediate benefits to organizations and individuals. PMID:17099107

  3. Evaluation of Two Methods of Prompting Drivers to Use Specific Exits on Conflicts between Vehicles at the Critical Exit

    ERIC Educational Resources Information Center

    Van Houten, Ron; Malenfant, J. E. Louis; Zhao, Nan; Ko, Byungkon; Van Houten, Jonathan

    2005-01-01

    The Florida Department of Transportation used a series of changeable-message signs that functioned as freeway guide signs to divert traffic to Universal Theme Park via one of two eastbound exits based on traffic congestion at the first of the two exits. An examination of crashes along the entire route indicated a statistically significant increase…

  4. Differences in Student Achievement between Early-Exit and Late-Exit Bilingual Programs: A Multiyear, Statewide Investigation

    ERIC Educational Resources Information Center

    Martinez, Rosa Maria

    2014-01-01

    Purpose The purpose of this study was to examine the difference between two bilingual program types: traditional early-exit and late-exit bilingual programs and academic achievement using archival data from the Texas Education Agency Public Education Information Management System. An examination of academic achievement rates across a 3-year period…

  5. Turbulent fluid-structure interaction of water-entry/exit of a rotating circular cylinder using SPH method

    NASA Astrophysics Data System (ADS)

    Ghazanfarian, Jafar; Saghatchi, Roozbeh; Gorji-Bandpy, Mofid

    2015-12-01

    This paper studies the two-dimensional (2D) water-entry and exit of a rotating circular cylinder using the Sub-Particle Scale (SPS) turbulence model of a Lagrangian particle-based Smoothed-Particle Hydrodynamics (SPH) method. The full Navier-Stokes (NS) equations along with the continuity have been solved as the governing equations of the problem. The accuracy of the numerical code is verified using the case of water-entry and exit of a nonrotating circular cylinder. The numerical simulations of water-entry and exit of the rotating circular cylinder are performed at Froude numbers of 2, 5, 8, and specific gravities of 0.25, 0.5, 0.75, 1, 1.75, rotating at the dimensionless rates of 0, 0.25, 0.5, 0.75. The effect of governing parameters and vortex shedding behind the cylinder on the trajectory curves, velocity components in the flow field, and the deformation of free surface for both cases have been investigated in detail. It is seen that the rotation has a great effect on the curvature of the trajectory path and velocity components in water-entry and exit cases due to the interaction of imposed lift and drag forces with the inertia force.

  6. A method for calculating strut and splitter plate noise in exit ducts: Theory and verification

    NASA Technical Reports Server (NTRS)

    Fink, M. R.

    1978-01-01

    Portions of a four-year analytical and experimental investigation relative to noise radiation from engine internal components in turbulent flow are summarized. Spectra measured for such airfoils over a range of chord, thickness ratio, flow velocity, and turbulence level were compared with predictions made by an available rigorous thin-airfoil analytical method. This analysis included the effects of flow compressibility and source noncompactness. Generally good agreement was obtained. This noise calculation method for isolated airfoils in turbulent flow was combined with a method for calculating transmission of sound through a subsonic exit duct and with an empirical far-field directivity shape. These three elements were checked separately and were individually shown to give close agreement with data. This combination provides a method for predicting engine internally generated aft-radiated noise from radial struts and stators, and annular splitter rings. Calculated sound power spectra, directivity, and acoustic pressure spectra were compared with the best available data. These data were for noise caused by a fan exit duct annular splitter ring, larger-chord stator blades, and turbine exit struts.

  7. Drivers’ Visual Characteristics when Merging onto or Exiting an Urban Expressway

    PubMed Central

    Cheng, Ying; Gao, Li; Zhao, Yanan; Du, Feng

    2016-01-01

    The aim of this study is to examine drivers’ visual and driving behavior while merging onto or exiting an urban expressway with low and high traffic densities. The analysis was conducted according to three periods (approaching, merging or exiting, and accelerating or decelerating). A total of 10 subjects (8 males and 2 females) with ages ranging from 25 to 52 years old (M = 30.0 years old) participated in the study. The research was conducted in a natural driving situation, and the drivers’ eye movements were monitored and recorded using an eye tracking system. The results show that the influence of traffic density on the glance duration and scan duration is more significant when merging than when exiting. The results also demonstrate that the number of glances and the mean glance duration are mainly related to the driving task (e.g., the merging period). Therefore, drivers’ visual search strategies mainly depend on the current driving task. With regard to driving behavior, the variation tendencies of the duration and the velocity of each period are similar. These results support building an automated driving assistant system that can automatically identify gaps and accelerate or decelerate the car accordingly or provide suggestions to the driver to do so. PMID:27657888

  8. 29 CFR 1910.37 - Maintenance, safeguards, and operational features for exit routes.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...., sprinkler systems, alarm systems, fire doors, exit lighting) must be in proper working order at all times... visible and marked by a sign reading “Exit.” (3) Each exit route door must be free of decorations or signs that obscure the visibility of the exit route door. (4) If the direction of travel to the exit or...

  9. 29 CFR 1910.37 - Maintenance, safeguards, and operational features for exit routes.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...., sprinkler systems, alarm systems, fire doors, exit lighting) must be in proper working order at all times... visible and marked by a sign reading “Exit.” (3) Each exit route door must be free of decorations or signs that obscure the visibility of the exit route door. (4) If the direction of travel to the exit or...

  10. 29 CFR 1910.37 - Maintenance, safeguards, and operational features for exit routes.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...., sprinkler systems, alarm systems, fire doors, exit lighting) must be in proper working order at all times... visible and marked by a sign reading “Exit.” (3) Each exit route door must be free of decorations or signs that obscure the visibility of the exit route door. (4) If the direction of travel to the exit or...

  11. 29 CFR 1910.37 - Maintenance, safeguards, and operational features for exit routes.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...., sprinkler systems, alarm systems, fire doors, exit lighting) must be in proper working order at all times... visible and marked by a sign reading “Exit.” (3) Each exit route door must be free of decorations or signs that obscure the visibility of the exit route door. (4) If the direction of travel to the exit or...

  12. A Case Report of Rash at Peritoneal Dialysis Exit Site

    PubMed Central

    Gosmanova, Elvira O.; Ezumba, Ikena; Fisher, Kristopher R.; Cleveland, Kerry O.

    2015-01-01

    The International Society for Peritoneal Dialysis recommends the regular application of topical antibiotic-containing preparations in addition to a routine exit site care to reduce the risk of exit site infection (ESI). Among these prophylactic antimicrobial preparations, topical gentamicin is one of the widely used and effective antibiotics for prevention of ESI and peritonitis in peritoneal dialysis (PD) patients. Overall, topical gentamicin is well tolerated; however, its use can be associated with the development of allergic contact dermatitis (ACD). We describe a first reported case of PD catheter exit site contact ACD due to topical gentamicin mimicking ESI. The patient in this report developed worsening violaceous in color and pruritic rash surrounding the PD catheter exit site that appeared 3 weeks after the initiation of gentamicin cream. The association between development of rash and initiation of topical gentamicin led to a suspicion of local reaction to gentamicin rather than ESI. Skin biopsy confirmed ACD. Discontinuation of the provoking agent and subsequent treatment with topical hydrocortisone application led to a resolution of the exit site rash. Any rash at a PD catheter exit site should be considered infectious until proven otherwise. However, it is important to be aware of noninfectious etiologies of exit site rashes as the treatment of these 2 conditions differs. PMID:26668811

  13. Factors Associated With Premature Exits From Supported Housing

    PubMed Central

    Gabrielian, Sonya; Burns, Alaina V.; Nanda, Nupur; Hellemann, Gerhard; Kane, Vincent; Young, Alexander S.

    2015-01-01

    Objective Many homeless consumers who enroll in supported housing programs—which offer subsidized housing and supportive services—disengage prematurely, before placement in permanent community-based housing. This study explored factors associated with exiting a supported housing program before achieving housing placement. Methods With the use of administrative data, a roster was obtained for consumers enrolled in the Veterans Affairs (VA) Greater Los Angeles supported housing program from 2011 to 2012. Fewer (4%) consumers exited this program before achieving housing (“exiters”) compared with consumers described in national VA figures (18%). Exiters with available demographic data (N=51) were matched 1:1 on age, gender, marital status, and race-ethnicity with consumers housed through this program (“stayers,” N=51). Medical records were reviewed to compare diagnoses, health care utilization, housing histories, vocational history, and criminal justice involvement of exiters versus stayers. Exiters' housing outcomes were identified. Recursive partitioning identified variables that best differentiated exiters from stayers. Results Several factors were associated with premature exits from this supported housing program: residing in temporary housing on hospital grounds during program enrollment, poor adherence to outpatient care, substance use disorders, hepatitis C, chronic pain, justice involvement, frequent emergency department utilization, and medical-surgical admissions. The first of these factors and poor adherence to outpatient medical-surgical care best differentiated exiters from stayers. Moreover, >50% of exiters became street homeless or incarcerated after leaving the program. Conclusions In that diverse social factors, diagnoses, and health care utilization patterns were associated with premature disengagement from supported housing, future research is needed to implement and evaluate rehabilitative services that address these factors, adapted to

  14. Jet engine nozzle exit configurations and associated systems and methods

    NASA Technical Reports Server (NTRS)

    Mengle, Vinod G. (Inventor)

    2011-01-01

    Nozzle exit configurations and associated systems and methods are disclosed. An aircraft system in accordance with one embodiment includes a jet engine exhaust nozzle having an internal flow surface and an exit aperture, with the exit aperture having a perimeter that includes multiple projections extending in an aft direction. Aft portions of individual neighboring projections are spaced apart from each other by a gap, and a geometric feature of the multiple can change in a monotonic manner along at least a portion of the perimeter.

  15. Jet Engine Nozzle Exit Configurations and Associated Systems and Methods

    NASA Technical Reports Server (NTRS)

    Mengle, Vinod G. (Inventor)

    2013-01-01

    Nozzle exit configurations and associated systems and methods are disclosed. An aircraft system in accordance with one embodiment includes a jet engine exhaust nozzle having an internal flow surface and an exit aperture, with the exit aperture having a perimeter that includes multiple projections extending in an aft direction. Aft portions of individual neighboring projections are spaced apart from each other by a gap, and a geometric feature of the multiple can change in a monotonic manner along at least a portion of the perimeter.

  16. Relationships among exit velocity, cortisol, and carcass characteristics of beef heifers

    Technology Transfer Automated Retrieval System (TEKTRAN)

    One hundred ninety-nine crossbred beef heifer calves (205 ± 7.9 kg initial BW) were used in a 44-d receiving trial with 2 dietary treatments (9 pens/treatment) in a completely randomized design. Heifers were weighed and bled on d 0, 16, 30, and 44 after arrival. Blood was collected by jugular venipu...

  17. Exploring the Use of Statewide Exit Exams to Spread Innovation--The Example of "Context" in Science Tasks from an International Comparative Perspective

    ERIC Educational Resources Information Center

    Kuhn, Svenja Mareike

    2011-01-01

    Many innovation-oriented concepts have recently been discussed as means to improve science education and instruction as well as the corresponding tests and exit exams. So far, empirical evidence of whether these new concepts for exam tasks actually find their way into the exam practice is still pending. This contribution takes up this desideratum…

  18. BASEMENT, A view looking east into Room 24. An exit ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    BASEMENT, A view looking east into Room 24. An exit door is at the far end - Department of Energy, Mound Facility, Hydrolysis House Building (HH Building), One Mound Road, Miamisburg, Montgomery County, OH

  19. Interior detail of exit door on second floor at north ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior detail of exit door on second floor at north end; camera facing north. - Mare Island Naval Shipyard, WAVES Officers Quarters, Cedar Avenue, west side between Tisdale Avenue & Eighth Street, Vallejo, Solano County, CA

  20. 14 CFR 23.811 - Emergency exit marking.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... airplane by— (1) A conspicuous visual identification scheme; and (2) A permanent decal or placard on or... illumination is essentially the same. (c) In addition, when certification to the emergency exit provisions...

  1. Behavior of Ants Escaping from a Single-Exit Room

    PubMed Central

    Wang, Shujie; Lv, Wei; Song, Weiguo

    2015-01-01

    To study the rules of ant behavior and group-formation phenomena, we examined the behaviors of Camponotus japonicus, a species of large ant, in a range of situations. For these experiments, ants were placed inside a rectangular chamber with a single exit that also contained a filter paper soaked in citronella oil, a powerful repellent. The ants formed several groups as they moved toward the exit to escape. We measured the time intervals between individual escapes in six versions of the experiment, each containing an exit of a different width, to quantify the movement of the groups. As the ants exited the chamber, the time intervals between individual escapes changed and the frequency distribution of the time intervals exhibited exponential decay. We also investigated the relationship between the number of ants in a group and the group flow rate. PMID:26125191

  2. Direct exit-wave reconstruction from a single defocused image.

    PubMed

    Morgan, A J; Martin, A V; D'Alfonso, A J; Putkunz, C T; Allen, L J

    2011-01-01

    We propose a direct, non-iterative method for the exact recovery of the complex wave in the exit-surface plane of a coherently illuminated object from a single defocused image. The method is applicable for a wide range of illumination conditions. The defocus range is subject to certain conditions, which if satisfied allow the complex exit-surface wave to be directly recovered by solving a set of linear equations. These linear equations, whose coefficients depend on the incident illumination, are obtained by analyzing the autocorrelation function of an auxiliary wave which is related to the exit-surface wave in a simple way. This autocorrelation is constructed by taking the inverse Fourier transform of the defocused image. We present an experimental proof of concept by recovering the exit-surface wave of a microfiber illuminated by a plane wave formed using a HeNe laser.

  3. Exit, punishment and rewards in commons dilemmas: an experimental study.

    PubMed

    Bravo, Giangiacomo; Squazzoni, Flaminio

    2013-01-01

    Commons dilemmas are interaction situations where a common good is provided or exploited by a group of individuals so that optimal collective outcomes clash with private interests. Although in these situations, social norms and institutions exist that might help individuals to cooperate, little is known about the interaction effects between positive and negative incentives and exit options by individuals. We performed a modified public good game experiment to examine the effect of exit, rewards and punishment, as well as the interplay between exit and rewards and punishment. We found that punishment had a stronger effect than rewards on cooperation if considered by itself, whereas rewards had a stronger effect when combined with voluntary participation. This can be explained in terms of the 'framing effect', i.e., as the combination of exit and rewards might induce people to attach higher expected payoffs to cooperative strategies and expect better behaviour from others. PMID:23936356

  4. Behavior of Ants Escaping from a Single-Exit Room.

    PubMed

    Wang, Shujie; Lv, Wei; Song, Weiguo

    2015-01-01

    To study the rules of ant behavior and group-formation phenomena, we examined the behaviors of Camponotus japonicus, a species of large ant, in a range of situations. For these experiments, ants were placed inside a rectangular chamber with a single exit that also contained a filter paper soaked in citronella oil, a powerful repellent. The ants formed several groups as they moved toward the exit to escape. We measured the time intervals between individual escapes in six versions of the experiment, each containing an exit of a different width, to quantify the movement of the groups. As the ants exited the chamber, the time intervals between individual escapes changed and the frequency distribution of the time intervals exhibited exponential decay. We also investigated the relationship between the number of ants in a group and the group flow rate.

  5. North wall, near east end, showing exhaust fan and exit ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    North wall, near east end, showing exhaust fan and exit (series 3 of 4) - Bureau of Mines Metallurgical Research Laboratory, Original Building, Date Street north of U.S. Highway 93, Boulder City, Clark County, NV

  6. 108. Cylindrical chamber where gas exits stove to below ground ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    108. Cylindrical chamber where gas exits stove to below ground flue that leads to stack. - Sloss-Sheffield Steel & Iron, First Avenue North Viaduct at Thirty-second Street, Birmingham, Jefferson County, AL

  7. CANAL EXITING FLUME AND BEGINNING EARTHLINED MAIN SECTION AT MOUTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CANAL EXITING FLUME AND BEGINNING EARTH-LINED MAIN SECTION AT MOUTH OF PLATTE RIVER CANYON. VIEW TO WEST - High Line Canal, Mouth of South Platte River to confluence with Second Creek, Denver, Denver County, CO

  8. Interior, second floor, south side, doors to emergency exit chute ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior, second floor, south side, doors to emergency exit chute open, showing the chute. - Fitzsimons General Hospital, Nurses' Quarters, Southeast Corner of West McAfee Avenue & South Hickey Street, Aurora, Adams County, CO

  9. East (gable end) and south sides. Emergency exit chute on ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    East (gable end) and south sides. Emergency exit chute on south side. - Fitzsimons General Hospital, Nurses' Quarters, Southeast Corner of West McAfee Avenue & South Hickey Street, Aurora, Adams County, CO

  10. Interior, second floor, south side, doors to emergency exit chute. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior, second floor, south side, doors to emergency exit chute. - Fitzsimons General Hospital, Nurses' Quarters, Southeast Corner of West McAfee Avenue & South Hickey Street, Aurora, Adams County, CO

  11. ARROYO SECO PARKWAY SOUTHBOUND LANES AND EXIT RAMP TO ORANGE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ARROYO SECO PARKWAY SOUTHBOUND LANES AND EXIT RAMP TO ORANGE GROVE AVENUE. ORANGE GROVE AVENUE BRIDGE IN REAR. LOOKING 278°W - Arroyo Seco Parkway, Orange Grove Avenue Bridge, Milepost 30.59, Los Angeles, Los Angeles County, CA

  12. Influence of Flow Swirling and Exit Shape of Barrel Nozzle on Cold Spraying

    NASA Astrophysics Data System (ADS)

    Klinkov, S. V.; Kosarev, V. F.; Zaikovskii, V. N.

    2011-06-01

    Traditionally, in cold spray two-phase supersonic jet formed with the help of converging-diverging nozzle are used. In this study an alternative design of cold spray nozzle is proposed in which a high velocity two-phase flow is created using an intense flow swirling in a constant section barrel (cylinder) with double-edged bevel exit. As a result, a high velocity gas-powder mixture jet is produced presenting a fan-shaped jet spreading at a large angle in one plane and approximately of equal size along the normal to this plane. This results in greater angles of particle deposition and, hence, in larger deposition widths, with the maximum width of deposition spot reaching 25 barrel diameters. The performed experimental study proves the new nozzle design to be appropriate for deposition of cold-sprayed coatings.

  13. The effects of initial jet exit conditions on plume resonance

    NASA Technical Reports Server (NTRS)

    Ponton, Michael K.; Seiner, John M.

    1989-01-01

    The acoustic emission and boundary layer of a cold jet issuing from an underexpanded sonic nozzle have been measured for lip thicknesses of the nozzle exit varying from 0.015-0.625 nozzle diameters. Near-field acoustic data demonstrate that the amplitude and frequency of certain modes of screech and the dominant mode of instability which exists in the shear layer are dependent on nozzle lip thickness. Changes in momentum thickness due to variations in the nozzle exit were also quantified.

  14. 49 CFR 393.62 - Emergency exits for buses.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 5 2011-10-01 2011-10-01 false Emergency exits for buses. 393.62 Section 393.62... NECESSARY FOR SAFE OPERATION Glazing and Window Construction § 393.62 Emergency exits for buses. (a) Buses manufactured on or after September 1, 1994. Each bus with a GVWR of 4,536 kg (10,000 pounds) or less must...

  15. 49 CFR 393.62 - Emergency exits for buses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Emergency exits for buses. 393.62 Section 393.62... NECESSARY FOR SAFE OPERATION Glazing and Window Construction § 393.62 Emergency exits for buses. (a) Buses manufactured on or after September 1, 1994. Each bus with a GVWR of 4,536 kg (10,000 pounds) or less must...

  16. Intelligent Exit-Selection Behaviors during a Room Evacuation

    NASA Astrophysics Data System (ADS)

    Zarita, Zainuddin; Lim Eng, Aik

    2012-01-01

    A modified version of the existing cellular automata (CA) model is proposed to simulate an evacuation procedure in a classroom with and without obstacles. Based on the numerous literature on the implementation of CA in modeling evacuation motions, it is notable that most of the published studies do not take into account the pedestrian's ability to select the exit route in their models. To resolve these issues, we develop a CA model incorporating a probabilistic neural network for determining the decision-making ability of the pedestrians, and simulate an exit-selection phenomenon in the simulation. Intelligent exit-selection behavior is observed in our model. From the simulation results, it is observed that occupants tend to select the exit closest to them when the density is low, but if the density is high they will go to an alternative exit so as to avoid a long wait. This reflects the fact that occupants may not fully utilize multiple exits during evacuation. The improvement in our proposed model is valuable for further study and for upgrading the safety aspects of building designs.

  17. Spatial signals link exit from mitosis to spindle position

    PubMed Central

    Falk, Jill Elaine; Tsuchiya, Dai; Verdaasdonk, Jolien; Lacefield, Soni; Bloom, Kerry; Amon, Angelika

    2016-01-01

    In budding yeast, if the spindle becomes mispositioned, cells prevent exit from mitosis by inhibiting the mitotic exit network (MEN). The MEN is a signaling cascade that localizes to spindle pole bodies (SPBs) and activates the phosphatase Cdc14. There are two competing models that explain MEN regulation by spindle position. In the 'zone model', exit from mitosis occurs when a MEN-bearing SPB enters the bud. The 'cMT-bud neck model' posits that cytoplasmic microtubule (cMT)-bud neck interactions prevent MEN activity. Here we find that 1) eliminating cMT– bud neck interactions does not trigger exit from mitosis and 2) loss of these interactions does not precede Cdc14 activation. Furthermore, using binucleate cells, we show that exit from mitosis occurs when one SPB enters the bud despite the presence of a mispositioned spindle. We conclude that exit from mitosis is triggered by a correctly positioned spindle rather than inhibited by improper spindle position. DOI: http://dx.doi.org/10.7554/eLife.14036.001 PMID:27166637

  18. Linguistic Theory and Actual Language.

    ERIC Educational Resources Information Center

    Segerdahl, Par

    1995-01-01

    Examines Noam Chomsky's (1957) discussion of "grammaticalness" and the role of linguistics in the "correct" way of speaking and writing. It is argued that the concern of linguistics with the tools of grammar has resulted in confusion, with the tools becoming mixed up with the actual language, thereby becoming the central element in a metaphysical…

  19. El Observatorio Gemini - Status actual

    NASA Astrophysics Data System (ADS)

    Levato, H.

    Se hace una breve descripción de la situación actual del Observatorio Gemini y de las últimas decisiones del Board para incrementar la eficiencia operativa. Se hace también una breve referencia al uso argentino del observatorio.

  20. A Modified EXIT-to-ECMO with Optional Reservoir Circuit for Use during an EXIT Procedure Requiring Thoracic Surgery.

    PubMed

    Matte, Gregory S; Connor, Kevin R; Toutenel, Nathalia A; Gottlieb, Danielle; Fynn-Thompson, Francis

    2016-03-01

    A 34 year old mother with a history of polyhydraminos and premature rupture of membranes presented for an ex utero intrapartum treatment (EXIT) procedure to deliver her 34 week gestation fetus. The fetus had been diagnosed with a large cervical mass which significantly extended into the right chest. The mass compressed and deviated the airway and major neck vessels posteriorly. Imaging also revealed possible tumor involvement with the superior vena cava and right atrium. The plan was for potential extracorporeal membrane oxygenation (ECMO) during the EXIT procedure (EXIT-to-ECMO) and the potential for traditional cardiopulmonary bypass (CPB) for mediastinal tumor resection. A Modified EXIT-To-ECMO with Optional Reservoir (METEOR) circuit was devised to satisfy both therapies. A fetal airway could not be established during the EXIT procedure and so the EXIT-to-ECMO strategy was utilized. The fetus was then delivered and transferred to an adjoining operating room (OR). Traditional cardiopulmonary bypass with a cardiotomy venous reservoir (CVR) was utilized during the establishment of an airway, tumor biopsy and partial resection. The patient was eventually transitioned to our institution's standard ECMO circuit and then transferred to the intensive care unit. The patient was weaned from ECMO on day of life (DOL) eight and had a successful tumor resection on DOL 11. The patient required hospitalization for numerous interventions including cardiac surgery at 4 months of age. She was discharged to home at 5 months of age. PMID:27134307

  1. A Modified EXIT-to-ECMO with Optional Reservoir Circuit for Use during an EXIT Procedure Requiring Thoracic Surgery.

    PubMed

    Matte, Gregory S; Connor, Kevin R; Toutenel, Nathalia A; Gottlieb, Danielle; Fynn-Thompson, Francis

    2016-03-01

    A 34 year old mother with a history of polyhydraminos and premature rupture of membranes presented for an ex utero intrapartum treatment (EXIT) procedure to deliver her 34 week gestation fetus. The fetus had been diagnosed with a large cervical mass which significantly extended into the right chest. The mass compressed and deviated the airway and major neck vessels posteriorly. Imaging also revealed possible tumor involvement with the superior vena cava and right atrium. The plan was for potential extracorporeal membrane oxygenation (ECMO) during the EXIT procedure (EXIT-to-ECMO) and the potential for traditional cardiopulmonary bypass (CPB) for mediastinal tumor resection. A Modified EXIT-To-ECMO with Optional Reservoir (METEOR) circuit was devised to satisfy both therapies. A fetal airway could not be established during the EXIT procedure and so the EXIT-to-ECMO strategy was utilized. The fetus was then delivered and transferred to an adjoining operating room (OR). Traditional cardiopulmonary bypass with a cardiotomy venous reservoir (CVR) was utilized during the establishment of an airway, tumor biopsy and partial resection. The patient was eventually transitioned to our institution's standard ECMO circuit and then transferred to the intensive care unit. The patient was weaned from ECMO on day of life (DOL) eight and had a successful tumor resection on DOL 11. The patient required hospitalization for numerous interventions including cardiac surgery at 4 months of age. She was discharged to home at 5 months of age.

  2. A Modified EXIT-to-ECMO with Optional Reservoir Circuit for Use during an EXIT Procedure Requiring Thoracic Surgery

    PubMed Central

    Matte, Gregory S.; Connor, Kevin R.; Toutenel, Nathalia A.; Gottlieb, Danielle; Fynn-Thompson, Francis

    2016-01-01

    Abstract: A 34 year old mother with a history of polyhydraminos and premature rupture of membranes presented for an ex utero intrapartum treatment (EXIT) procedure to deliver her 34 week gestation fetus. The fetus had been diagnosed with a large cervical mass which significantly extended into the right chest. The mass compressed and deviated the airway and major neck vessels posteriorly. Imaging also revealed possible tumor involvement with the superior vena cava and right atrium. The plan was for potential extracorporeal membrane oxygenation (ECMO) during the EXIT procedure (EXIT-to-ECMO) and the potential for traditional cardiopulmonary bypass (CPB) for mediastinal tumor resection. A Modified EXIT-To-ECMO with Optional Reservoir (METEOR) circuit was devised to satisfy both therapies. A fetal airway could not be established during the EXIT procedure and so the EXIT-to-ECMO strategy was utilized. The fetus was then delivered and transferred to an adjoining operating room (OR). Traditional cardiopulmonary bypass with a cardiotomy venous reservoir (CVR) was utilized during the establishment of an airway, tumor biopsy and partial resection. The patient was eventually transitioned to our institution's standard ECMO circuit and then transferred to the intensive care unit. The patient was weaned from ECMO on day of life (DOL) eight and had a successful tumor resection on DOL 11. The patient required hospitalization for numerous interventions including cardiac surgery at 4 months of age. She was discharged to home at 5 months of age. PMID:27134307

  3. Mitotic Exit Control as an Evolved Complex System

    SciTech Connect

    Bosl, W; Li, R

    2005-04-25

    The exit from mitosis is the last critical decision a cell has to make during a division cycle. A complex regulatory system has evolved to evaluate the success of mitotic events and control this decision. Whereas outstanding genetic work in yeast has led to rapid discovery of a large number of interacting genes involved in the control of mitotic exit, it has also become increasingly difficult to comprehend the logic and mechanistic features embedded in the complex molecular network. Our view is that this difficulty stems in part from the attempt to explain mitotic exit control using concepts from traditional top-down engineering design, and that exciting new results from evolutionary engineering design applied to networks and electronic circuits may lend better insights. We focus on four particularly intriguing features of the mitotic exit control system: the two-stepped release of Cdc14; the self-activating nature of Tem1 GTPase; the spatial sensor associated with the spindle pole body; and the extensive redundancy in the mitotic exit network. We attempt to examine these design features from the perspective of evolutionary design and complex system engineering.

  4. Density and compressibility effects in turbulent subsonic jets part 1: mean velocity field

    NASA Astrophysics Data System (ADS)

    Wang, Zhexuan; Andreopoulos, Yiannis

    2010-02-01

    The behavior of compressible jets originated from initially turbulent pipe flows issuing in still air has been investigated at three different subsonic Mach numbers, 0.3, 0.6 and 0.9. Helium, nitrogen and krypton gases were used to generate the jet flows and investigate the additional effects of density on the flow structure. Particle image velocimetry, high-frequency response pressure transducers and thermocouples were used to obtain velocity, Mach number and total temperature measurements inside the flow field. The jets were formed at the exit of an adiabatic compressible frictional turbulent pipe flow, which was developing toward its corresponding sonic conditions inside the pipe, and continued to expand within the first four diameters distance after it exited the pipe. Theoretical considerations based on flow self-similarity were used to obtain the decay of Mach number along the centerline of the jets for the first time. It was found that this decay depends on two contributions, one from the velocity field which is inversely proportional to the distance from the exit and one from the thermal field which is proportional to this distance. As a result, a small non-linearity in the variation of the inverse Mach number with downstream distance was found. The decay of the Mach number at the centerline of the axisymmetric jets increases by increasing the initial Mach number at the exit of the flow for all jets. The decay of mean velocity at the centerline of the jets is also higher at higher exit Mach numbers. However, the velocity non-dimensionalized by the exit velocity seems to decrease faster at low exit Mach numbers, suggesting a reduced mixing with increasing exit flow Mach numbers. Helium jets were found to have the largest spreading rate among the three different gas jets used in the present investigation, while krypton jets had the lowest spreading rate. The spreading rate of each gas decreases with increasing its kinetic energy relatively to its internal

  5. The influence of the stagnation zone on the fluid dynamics at the nozzle exit of a confined and submerged impinging jet

    NASA Astrophysics Data System (ADS)

    Jeffers, Nicholas; Stafford, Jason; Conway, Ciaran; Punch, Jeff; Walsh, Edmond

    2016-02-01

    Low profile impinging jets provide a means to achieve high heat transfer coefficients while occupying a small quantity of space. Consequently, they are found in many engineering applications such as electronics cooling, annealing of metals, food processing, and others. This paper investigates the influence of the stagnation zone fluid dynamics on the nozzle exit flow condition of a low profile, submerged, and confined impinging water jet. The jet was geometrically constrained to a round, 16-mm diameter, square-edged nozzle at a jet exit to target surface spacing ( H/ D) that varied between 0.25 < {{ H}{/}{ D}} < 8.75. The influence of turbulent flow regimes is the main focus of this paper; however, laminar flow data are also presented between 1350 < Re < 17{,}300. A custom measurement facility was designed and commissioned to utilise particle image velocimetry in order to quantitatively measure the fluid dynamics both before and after the jet exits its nozzle. The velocity profiles are normalised with the mean velocity across the nozzle exit, and turbulence statistics are also presented. The primary objective of this paper is to present accurate flow profiles across the nozzle exit of an impinging jet confined to a low H/ D, with a view to guide the boundary conditions chosen for numerical simulations confined to similar constraints. The results revealed in this paper suggest that the fluid dynamics in the stagnation zone strongly influences the nozzle exit velocity profile at confinement heights between 0 < {{ H}{/}{ D}} < 1. This is of particular relevance with regard to the choice of inlet boundary conditions in numerical models, and it was found that it is necessary to model a jet tube length {{ L}{/}{ D}} > 0.5—where D is the inner diameter of the jet—in order to minimise modelling uncertainty.

  6. Small protein domains fold inside the ribosome exit tunnel.

    PubMed

    Marino, Jacopo; von Heijne, Gunnar; Beckmann, Roland

    2016-03-01

    Cotranslational folding of small protein domains within the ribosome exit tunnel may be an important cellular strategy to avoid protein misfolding. However, the pathway of cotranslational folding has so far been described only for a few proteins, and therefore, it is unclear whether folding in the ribosome exit tunnel is a common feature for small protein domains. Here, we have analyzed nine small protein domains and determined at which point during translation their folding generates sufficient force on the nascent chain to release translational arrest by the SecM arrest peptide, both in vitro and in live E. coli cells. We find that all nine protein domains initiate folding while still located well within the ribosome exit tunnel. PMID:26879042

  7. Cotranslational Protein Folding inside the Ribosome Exit Tunnel

    PubMed Central

    Nilsson, Ola B.; Hedman, Rickard; Marino, Jacopo; Wickles, Stephan; Bischoff, Lukas; Johansson, Magnus; Müller-Lucks, Annika; Trovato, Fabio; Puglisi, Joseph D.; O’Brien, Edward P.; Beckmann, Roland; von Heijne, Gunnar

    2015-01-01

    Summary At what point during translation do proteins fold? It is well established that proteins can fold cotranslationally outside the ribosome exit tunnel, whereas studies of folding inside the exit tunnel have so far detected only the formation of helical secondary structure and collapsed or partially structured folding intermediates. Here, using a combination of cotranslational nascent chain force measurements, inter-subunit fluorescence resonance energy transfer studies on single translating ribosomes, molecular dynamics simulations, and cryoelectron microscopy, we show that a small zinc-finger domain protein can fold deep inside the vestibule of the ribosome exit tunnel. Thus, for small protein domains, the ribosome itself can provide the kind of sheltered folding environment that chaperones provide for larger proteins. PMID:26321634

  8. Gas turbine combustor exit piece with hinged connections

    DOEpatents

    Charron, Richard C.; Pankey, William W.

    2016-04-26

    An exit piece (66) with an inlet throat (67) that conducts a combustion gas flow (36A) in a path (82) from a combustor (63) to an annular chamber (68) that feeds the first blade section (37) of a gas turbine (26). The exit piece further includes an outlet portion (69) that forms a circumferential segment of the annular chamber. The outlet portion interconnects with adjacent outlet portions by hinges (78A, 78B, 80A, 80B). Each hinge may have a hinge axis (82A, 82B) parallel to a centerline (21) of the turbine. Respective gas flows (36A) are configured by an assembly (60) of the exit pieces to converge on the feed chamber (68) into a uniform helical flow that drives the first blade section with minimal circumferential variations in force.

  9. How People Actually Use Thermostats

    SciTech Connect

    Meier, Alan; Aragon, Cecilia; Hurwitz, Becky; Mujumdar, Dhawal; Peffer, Therese; Perry, Daniel; Pritoni, Marco

    2010-08-15

    Residential thermostats have been a key element in controlling heating and cooling systems for over sixty years. However, today's modern programmable thermostats (PTs) are complicated and difficult for users to understand, leading to errors in operation and wasted energy. Four separate tests of usability were conducted in preparation for a larger study. These tests included personal interviews, an on-line survey, photographing actual thermostat settings, and measurements of ability to accomplish four tasks related to effective use of a PT. The interviews revealed that many occupants used the PT as an on-off switch and most demonstrated little knowledge of how to operate it. The on-line survey found that 89% of the respondents rarely or never used the PT to set a weekday or weekend program. The photographic survey (in low income homes) found that only 30% of the PTs were actually programmed. In the usability test, we found that we could quantify the difference in usability of two PTs as measured in time to accomplish tasks. Users accomplished the tasks in consistently shorter times with the touchscreen unit than with buttons. None of these studies are representative of the entire population of users but, together, they illustrate the importance of improving user interfaces in PTs.

  10. Intermittency and velocity fluctuations in hopper flows prone to clogging.

    PubMed

    Thomas, C C; Durian, D J

    2016-08-01

    We study experimentally the dynamics of granular media in a discharging hopper. In such flows, there often appears to be a critical outlet size D_{c} such that the flow never clogs for D>D_{c}. We report on the time-averaged velocity distributions, as well as temporal intermittency in the ensemble-averaged velocity of grains in a viewing window, for both DD_{c}, near and far from the outlet. We characterize the velocity distributions by the standard deviation and the skewness of the distribution of vertical velocities. We propose a measure for intermittency based on the two-sample Kolmogorov-Smirnov D_{KS} statistic for the velocity distributions as a function of time. We find that there is no discontinuity or kink in these various measures as a function of hole size. This result supports the proposition that there is no well-defined D_{c} and that clogging is always possible. Furthermore, the intermittency time scale of the flow is set by the speed of the grains at the hopper exit. This latter finding is consistent with a model of clogging as the independent sampling for stable configurations at the exit with a rate set by the exiting grain speed [C. C. Thomas and D. J. Durian, Phys. Rev. Lett. 114, 178001 (2015)PRLTAO0031-900710.1103/PhysRevLett.114.178001].

  11. Intermittency and velocity fluctuations in hopper flows prone to clogging

    NASA Astrophysics Data System (ADS)

    Thomas, C. C.; Durian, D. J.

    2016-08-01

    We study experimentally the dynamics of granular media in a discharging hopper. In such flows, there often appears to be a critical outlet size Dc such that the flow never clogs for D >Dc . We report on the time-averaged velocity distributions, as well as temporal intermittency in the ensemble-averaged velocity of grains in a viewing window, for both D Dc , near and far from the outlet. We characterize the velocity distributions by the standard deviation and the skewness of the distribution of vertical velocities. We propose a measure for intermittency based on the two-sample Kolmogorov-Smirnov DKS statistic for the velocity distributions as a function of time. We find that there is no discontinuity or kink in these various measures as a function of hole size. This result supports the proposition that there is no well-defined Dc and that clogging is always possible. Furthermore, the intermittency time scale of the flow is set by the speed of the grains at the hopper exit. This latter finding is consistent with a model of clogging as the independent sampling for stable configurations at the exit with a rate set by the exiting grain speed [C. C. Thomas and D. J. Durian, Phys. Rev. Lett. 114, 178001 (2015), 10.1103/PhysRevLett.114.178001].

  12. Intermittency and velocity fluctuations in hopper flows prone to clogging.

    PubMed

    Thomas, C C; Durian, D J

    2016-08-01

    We study experimentally the dynamics of granular media in a discharging hopper. In such flows, there often appears to be a critical outlet size D_{c} such that the flow never clogs for D>D_{c}. We report on the time-averaged velocity distributions, as well as temporal intermittency in the ensemble-averaged velocity of grains in a viewing window, for both DD_{c}, near and far from the outlet. We characterize the velocity distributions by the standard deviation and the skewness of the distribution of vertical velocities. We propose a measure for intermittency based on the two-sample Kolmogorov-Smirnov D_{KS} statistic for the velocity distributions as a function of time. We find that there is no discontinuity or kink in these various measures as a function of hole size. This result supports the proposition that there is no well-defined D_{c} and that clogging is always possible. Furthermore, the intermittency time scale of the flow is set by the speed of the grains at the hopper exit. This latter finding is consistent with a model of clogging as the independent sampling for stable configurations at the exit with a rate set by the exiting grain speed [C. C. Thomas and D. J. Durian, Phys. Rev. Lett. 114, 178001 (2015)PRLTAO0031-900710.1103/PhysRevLett.114.178001]. PMID:27627374

  13. Simulation of Water-Entry and Water-Exit Problems Using a Moving Mesh Algorithm

    NASA Astrophysics Data System (ADS)

    Panahi, Roozbeh

    2012-06-01

    Simulation of the water-entry and water-exit particularly, at the interface of two phases i.e. water and air due to the effect of flow-induced loads, gravity force and trapped air cushion presence is very complicated. This paper attempts to introduce a finite volume-based moving mesh algorithm in order to simulate such problems in a viscous incompressible two-phase medium. The algorithm employs a fractional step method to deal with the coupling between pressure and velocity fields. Interface is also captured by solving a volume fraction transport equation. A boundary-fitted body-attached mesh of quadrilateral Control Volumes (CVs) is implemented to record hydrodynamic time histories of loads, motions and interfacial flow changes around the structure. Forced water-exit of a cylinder is simulated based on the introduced algorithm, together with free symmetric and asymmetric water-entry of wedges. Results show that the presented algorithm is favorably capable of assessing such complexities when comparing to experimental data.

  14. Measurement of Initial Conditions at Nozzle Exit of High Speed Jets

    NASA Technical Reports Server (NTRS)

    Panda, J.; Zaman, K. B. M. Q.; Seasholtz, R. G.

    2004-01-01

    The time averaged and unsteady density fields close to the nozzle exit (0.1 less than or = x/D less than or = 2, x: downstream distance, D: jet diameter) of unheated free jets at Mach numbers of 0.95, 1.4, and 1.8 were measured using a molecular Rayleigh scattering based technique. The initial thickness of shear layer and its linear growth rate were determined from time-averaged density survey and a modeling process, which utilized the Crocco-Busemann equation to relate density profiles to velocity profiles. The model also corrected for the smearing effect caused by a relatively long probe length in the measured density data. The calculated shear layer thickness was further verified from a limited hot-wire measurement. Density fluctuations spectra, measured using a two-Photomultiplier-tube technique, were used to determine evolution of turbulent fluctuations in various Strouhal frequency bands. For this purpose spectra were obtained from a large number of points inside the flow; and at every axial station spectral data from all radial positions were integrated. The radially-integrated fluctuation data show an exponential growth with downstream distance and an eventual saturation in all Strouhal frequency bands. The initial level of density fluctuations was calculated by extrapolation to nozzle exit.

  15. Assessing University Students: Searching for an English Language Exit Test

    ERIC Educational Resources Information Center

    Qian, David D.

    2007-01-01

    In order to motivate university students to improve their English proficiency, the Hong Kong government decided to adopt a common exit English language test for all graduating students. In the process of selecting a suitable measure for this purpose, an empirical study with a sample of over 240 students was conducted to compare two English…

  16. Time to Say Goodbye to High School Exit Exams

    ERIC Educational Resources Information Center

    Bracey, Gerald W.

    2009-01-01

    In recent years, a concatenation of fears, pressures, and agendas has produced a new round of testing in the form of high school exit examinations. There has not, however, been an accompanying rush to see whether the exams do any good. No state has attempted to validate its test against external criteria: given the hyperbole surrounding the tests…

  17. 14 CFR 25.809 - Emergency exit arrangement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... during all lighting conditions with the landing gear extended as well as in all conditions of landing gear collapse. (b) Each emergency exit must be openable from the inside and the outside except that... attitude and in each of the attitudes corresponding to collapse of one or more legs of the landing...

  18. 14 CFR 25.809 - Emergency exit arrangement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... during all lighting conditions with the landing gear extended as well as in all conditions of landing gear collapse. (b) Each emergency exit must be openable from the inside and the outside except that... attitude and in each of the attitudes corresponding to collapse of one or more legs of the landing...

  19. 14 CFR 25.809 - Emergency exit arrangement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... during all lighting conditions with the landing gear extended as well as in all conditions of landing gear collapse. (b) Each emergency exit must be openable from the inside and the outside except that... attitude and in each of the attitudes corresponding to collapse of one or more legs of the landing...

  20. 14 CFR 25.809 - Emergency exit arrangement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... during all lighting conditions with the landing gear extended as well as in all conditions of landing gear collapse. (b) Each emergency exit must be openable from the inside and the outside except that... attitude and in each of the attitudes corresponding to collapse of one or more legs of the landing...

  1. 14 CFR 25.809 - Emergency exit arrangement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... during all lighting conditions with the landing gear extended as well as in all conditions of landing gear collapse. (b) Each emergency exit must be openable from the inside and the outside except that... attitude and in each of the attitudes corresponding to collapse of one or more legs of the landing...

  2. 14 CFR 25.813 - Emergency exit access.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... provided, there must be unobstructed cross-aisles at least 20 inches wide between main aisles. There must be— (1) A cross-aisle which leads directly to each passageway between the nearest main aisle and a Type A or B exit; and (2) A cross-aisle which leads to the immediate vicinity of each...

  3. Teachers' Interpretations of Exit Exam Scores and College Readiness

    ERIC Educational Resources Information Center

    McIntosh, Shelby

    2013-01-01

    This study examined teachers' interpretations of Virginia's high school exit exam policy through the teachers' responses to a survey. The survey was administered to teachers from one school district in Northern Virginia. The teachers selected for the survey taught a subject in which students must pass a Standards of Learning (SOL) test in order to…

  4. Gender and Politics at Work: Why Women Exit the Superintendency.

    ERIC Educational Resources Information Center

    Tallerico, Marilyn; And Others

    Findings of a study that explored reasons why women exit the superintendency are presented in this document. Data were collected through open-ended telephone interviews conducted with 20 women who left superintendencies within the past 7 years and with 4 women informants, all derived through snowball sampling. One-third had voluntarily exited…

  5. 24 CFR 3280.105 - Exit facilities; exterior doors.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Planning Considerations... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Exit facilities; exterior doors. 3280.105 Section 3280.105 Housing and Urban Development Regulations Relating to Housing and...

  6. 10 CFR 431.202 - Definitions concerning illuminated exit signs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Definitions concerning illuminated exit signs. 431.202 Section 431.202 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN... energy source, which have electrical characteristics that are essentially identical, and which do...

  7. 3. GENERAL EXTERIOR VIEW LOOKING NORTHWEST, SHOWING BARGE AFTER EXITING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. GENERAL EXTERIOR VIEW LOOKING NORTHWEST, SHOWING BARGE AFTER EXITING FROM DOWNSTREAM END OF NAVIGATION LOCK #1; SWING BRIDGE IS IN PROCESS OF CLOSING. - Bonneville Project, Navigation Lock No. 1, Oregon shore of Columbia River near first Powerhouse, Bonneville, Multnomah County, OR

  8. 14 CFR 23.805 - Flightcrew emergency exits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... accessible means of evacuation for the flightcrew, the following apply: (a) There must be either one... emergency exit must be located to allow rapid evacuation of the crew and have a size and shape of at least a... another approved location if the stowed device, or its attachment, would reduce the pilot's view; and...

  9. 14 CFR 23.805 - Flightcrew emergency exits.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... accessible means of evacuation for the flightcrew, the following apply: (a) There must be either one... emergency exit must be located to allow rapid evacuation of the crew and have a size and shape of at least a... another approved location if the stowed device, or its attachment, would reduce the pilot's view; and...

  10. 14 CFR 23.805 - Flightcrew emergency exits.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... accessible means of evacuation for the flightcrew, the following apply: (a) There must be either one... emergency exit must be located to allow rapid evacuation of the crew and have a size and shape of at least a... another approved location if the stowed device, or its attachment, would reduce the pilot's view; and...

  11. 14 CFR 23.805 - Flightcrew emergency exits.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... accessible means of evacuation for the flightcrew, the following apply: (a) There must be either one... emergency exit must be located to allow rapid evacuation of the crew and have a size and shape of at least a... another approved location if the stowed device, or its attachment, would reduce the pilot's view; and...

  12. 14 CFR 23.805 - Flightcrew emergency exits.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... accessible means of evacuation for the flightcrew, the following apply: (a) There must be either one... emergency exit must be located to allow rapid evacuation of the crew and have a size and shape of at least a... another approved location if the stowed device, or its attachment, would reduce the pilot's view; and...

  13. 14 CFR 23.811 - Emergency exit marking.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... inches high, be self-illuminated or independently, internally electrically illuminated, and have a... means of opening, must be conspicuously marked; (2) The identity and location of each emergency exit...— (i) Be self-illuminated with an initial brightness of at least 160 microlamberts; or (ii)...

  14. 14 CFR 23.811 - Emergency exit marking.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... inches high, be self-illuminated or independently, internally electrically illuminated, and have a... means of opening, must be conspicuously marked; (2) The identity and location of each emergency exit...— (i) Be self-illuminated with an initial brightness of at least 160 microlamberts; or (ii)...

  15. 14 CFR 23.811 - Emergency exit marking.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... inches high, be self-illuminated or independently, internally electrically illuminated, and have a... means of opening, must be conspicuously marked; (2) The identity and location of each emergency exit...— (i) Be self-illuminated with an initial brightness of at least 160 microlamberts; or (ii)...

  16. 14 CFR 23.811 - Emergency exit marking.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... inches high, be self-illuminated or independently, internally electrically illuminated, and have a... means of opening, must be conspicuously marked; (2) The identity and location of each emergency exit...— (i) Be self-illuminated with an initial brightness of at least 160 microlamberts; or (ii)...

  17. A Longitudinal Study of Welfare Exit among American Indian Families

    ERIC Educational Resources Information Center

    Pandey, Shanta; Guo, Baorong

    2007-01-01

    Data from a longitudinal survey of families from three reservations (Navajo Nation, San Carlos, and Salt River) in Arizona were used to examine their probability of welfare use. Logistic regression models were used to estimate the effects of individual, family, and structural factors on welfare exit. Results indicate that their probability of…

  18. 10 CFR 431.202 - Definitions concerning illuminated exit signs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... one manufacturer, having the same primary energy source, and which have essentially identical... 10 Energy 3 2012-01-01 2012-01-01 false Definitions concerning illuminated exit signs. 431.202 Section 431.202 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR...

  19. 10 CFR 431.202 - Definitions concerning illuminated exit signs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... one manufacturer, having the same primary energy source, and which have essentially identical... 10 Energy 3 2014-01-01 2014-01-01 false Definitions concerning illuminated exit signs. 431.202 Section 431.202 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR...

  20. 14 CFR 25.813 - Emergency exit access.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Emergency exit access. 25.813 Section 25.813 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Design and Construction Emergency Provisions §...

  1. 14 CFR 25.813 - Emergency exit access.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Emergency exit access. 25.813 Section 25.813 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Design and Construction Emergency Provisions §...

  2. Embracing the Exit: Assessment, Trust, and the Teaching of Writing

    ERIC Educational Resources Information Center

    Eng, Joseph

    2006-01-01

    Historically, the Composition Program at Eastern Washington University (EWU), a comprehensive university in Cheney, WA, required a single essay sample from each composition student as the final exit exam; in practice, a student passed or failed the course based on an in-class argumentative essay, written in three consecutive class periods. Such a…

  3. CA State Profile. California: California High School Exit Examination (CAHSEE)

    ERIC Educational Resources Information Center

    Center on Education Policy, 2010

    2010-01-01

    This paper provides information about California High School Exit Examination, a comprehensive standards-based exam. The purpose of the exam is to: (1) Determine prospective high school graduates' knowledge and skill levels relative to those needed for entry-level employment; (2) Determine prospective high school graduates' mastery of the state…

  4. INTERIOR DETAIL OF THE ARENA EXIT GATE AND VERTICAL LOUVERS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR DETAIL OF THE ARENA EXIT GATE AND VERTICAL LOUVERS AT THE TOP OF THE BLEACHER SEATING. VIEW FACING NORTHWEST - U.S. Naval Base, Pearl Harbor, Bloch Recreation Center & Arena, Between Center Drive & North Road near Nimitz Gate, Pearl City, Honolulu County, HI

  5. 45 CFR 670.34 - Entry and exit ports.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ANTARCTIC ANIMALS AND PLANTS Import Into and Export From the United States § 670.34 Entry and exit ports. (a... of Interior in 50 CFR part 14. The ports currently designated are: (1) Los Angeles, California. (2... Orleans, Louisiana. (7) New York, New York. (8) Seattle, Washington. (9) Dallas/Fort Worth, Texas....

  6. Senior Exit Plans Survey. State Summary Report. Class of 2007

    ERIC Educational Resources Information Center

    State of Hawaii Department of Education, 2008

    2008-01-01

    This report presents statewide, complex area, and individual school summaries of students' post-secondary plans for the year following their completion of high school. The Senior Exit Plans Survey (SEPS) Coordinator at each school, usually a school counselor, was responsible for distributing, collecting, checking, and returning the completed…

  7. Senior Exit Plans Survey. State Summary Report. Class of 2004.

    ERIC Educational Resources Information Center

    State of Hawaii Department of Education, 2004

    2004-01-01

    This report presents statewide, complex area, and individual school summaries of students? post-secondary plans for the year following their completion of high school. The Senior Exit Plans Survey (SEPS) Coordinator at each school, usually a school counselor, was responsible for distributing, collecting, checking, and returning the completed…

  8. 45 CFR 670.34 - Entry and exit ports.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... of Interior in 50 CFR part 14. The ports currently designated are: (1) Los Angeles, California. (2) San Francisco, California. (3) Miami, Florida. (4) Honolulu, Hawaii. (5) Chicago, Illinois. (6) New... ANTARCTIC ANIMALS AND PLANTS Import Into and Export From the United States § 670.34 Entry and exit ports....

  9. 45 CFR 670.34 - Entry and exit ports.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... of Interior in 50 CFR part 14. The ports currently designated are: (1) Los Angeles, California. (2) San Francisco, California. (3) Miami, Florida. (4) Honolulu, Hawaii. (5) Chicago, Illinois. (6) New... ANTARCTIC ANIMALS AND PLANTS Import Into and Export From the United States § 670.34 Entry and exit ports....

  10. Modeling States' Enactment of High School Exit Examination Policies

    ERIC Educational Resources Information Center

    Warren, John Robert; Kulick, Rachael B.

    2007-01-01

    We present five frameworks for explaining which U.S. states adopted high school exit examination policies at particular points in time. The frameworks correspond to issues of academic achievement, education spending, economic conditions, racial/ethnic heterogeneity and policy diffusion. Using event history techniques we find that states with…

  11. Chlamydial Lytic Exit from Host Cells Is Plasmid Regulated

    PubMed Central

    Yang, Chunfu; Starr, Tregei; Song, Lihua; Carlson, John H.; Sturdevant, Gail L.; Beare, Paul A.; Whitmire, William M.

    2015-01-01

    ABSTRACT Chlamydia trachomatis is an obligate intracellular bacterium that is a globally important human pathogen. The chlamydial plasmid is an attenuating virulence factor, but the molecular basis for attenuation is not understood. Chlamydiae replicate within a membrane-bound vacuole termed an inclusion, where they undergo a biphasic developmental growth cycle and differentiate from noninfectious into infectious organisms. Late in the developmental cycle, the fragile chlamydia-laden inclusion retains its integrity by surrounding itself with scaffolds of host cytoskeletal proteins. The ability of chlamydiae to developmentally free themselves from this cytoskeleton network is a fundamental virulence trait of the pathogen. Here, we show that plasmidless chlamydiae are incapable of disrupting their cytoskeletal entrapment and remain intracellular as stable mature inclusions that support high numbers of infectious organisms. By using deletion mutants of the eight plasmid-carried genes (Δpgp1 to Δpgp8), we show that Pgp4, a transcriptional regulator of multiple chromosomal genes, is required for exit. Exit of chlamydiae is dependent on protein synthesis and is inhibited by the compound C1, an inhibitor of the type III secretion system (T3S). Exit of plasmid-free and Δpgp4 organisms, which failed to lyse infected cells, was rescued by latrunculin B, an inhibitor of actin polymerization. Our findings describe a genetic mechanism of chlamydial exit from host cells that is dependent on an unknown pgp4-regulated chromosomal T3S effector gene. PMID:26556273

  12. View looking out of the Irving Powerhouse showing the exiting ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View looking out of the Irving Powerhouse showing the exiting water flowing south into the inlet of the Childs System. Looking south - Childs-Irving Hydroelectric Project, Irving System, Irving Powerhouse, Forest Service Road 708/502, Camp Verde, Yavapai County, AZ

  13. ARROYO SECO PARKWAY SOUTHBOUND LANES AND EXIT RAMP TO ORANGE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ARROYO SECO PARKWAY SOUTHBOUND LANES AND EXIT RAMP TO ORANGE GROVE AVENUE. ORANGE GROVE AVENUE BRIDGE IN REAR. NOTE IRRIGATION AND DRAINAGE FEATURES AT RIGHT. LOOKING 248°WSW - Arroyo Seco Parkway, Orange Grove Avenue Bridge, Milepost 30.59, Los Angeles, Los Angeles County, CA

  14. Velocity distributions in a hydrocyclone separator

    NASA Astrophysics Data System (ADS)

    Fisher, M. J.; Flack, R. D.

    The internal three-dimensional flow field in a hydrocyclone was studied using laser velocimetry. Seven axial planes were investigated for three different inlet flow rates and three independent and different rejects rates. Results at each measurement plane showed that the measured tangential velocity profile behaves like a forced vortex at the region near the air core, and like a free vortex in the outer portion of the flow. The peak nondimensional tangential velocity decreases as the distance from the inlet region increases, however, the peak dimensional tangential velocity increases as the distance from the inlet region increases. The nondimensional peak tangential velocities are approximately equal for all of the flow rates. The magnitude of the tangential velocity increased in the inner forced vortex region as the rejects rate was increased. Backflows exist in the axial velocity profile near the inlet region, but these reversed flows disappear in the exit region. The dimensional vorticity is proportional to inlet flow rate and decreases with increasing rejects flow rates.

  15. Comparability of Semester and Exit Exam Grades: Long-Term Effect of the Implementation of State-Wide Exit Exams

    ERIC Educational Resources Information Center

    Maag Merki, Katharina; Holmeier, Monika

    2015-01-01

    A goal in many countries is to institute state-wide exams to base student assessment more firmly on norms for all classes. This raises the question as to the extent to which greater standardization of grading practice can be reached by implementing state-wide exit exams. Since there is a lack of longitudinal studies, we analyzed the effect of the…

  16. Gait phase varies over velocities.

    PubMed

    Liu, Yancheng; Lu, Kun; Yan, Songhua; Sun, Ming; Lester, D Kevin; Zhang, Kuan

    2014-02-01

    We sought to characterize the percent (PT) of the phases of a gait cycle (GC) as velocity changes to establish norms for pathological gait characteristics with higher resolution technology. Ninety five healthy subjects (49 males and 46 females with age 34.9 ± 11.8 yrs, body weight 64.0 ± 11.7 kg and BMI 23.5 ± 3.6) were enrolled and walked comfortably on a 10-m walkway at self-selected slower, normal, and faster velocities. Walking was recorded with a high speed camera (250 frames per second) and the eight phases of a GC were determined by examination of individual frames for each subject. The correlation coefficients between the mean PT of the phases of the three velocities gaits and PT defined by previous publications were all greater than 0.99. The correlation coefficient between velocity and PT of gait phases is -0.83 for loading response (LR), -0.75 for mid stance (MSt), and -0.84 for pre-swing (PSw). While the PT of the phases of three velocities from this study are highly correlated with PT described by Dr. Jacquenlin Perry decades ago, actual PT of each phase varied amongst these individuals with the largest coefficient variation of 24.31% for IC with slower velocity. From slower to faster walk, the mean PT of MSt diminished from 35.30% to 25.33%. High resolution recording revealed ambiguity of some gait phase definitions, and these data may benefit GC characterization of normal and pathological gait in clinical practice. The study results indicate that one should consider individual variations and walking velocity when evaluating gaits of subjects using standard gait phase classification.

  17. The actual goals of geoethics

    NASA Astrophysics Data System (ADS)

    Nemec, Vaclav

    2014-05-01

    The most actual goals of geoethics have been formulated as results of the International Conference on Geoethics (October 2013) held at the geoethics birth-place Pribram (Czech Republic): In the sphere of education and public enlightenment an appropriate needed minimum know how of Earth sciences should be intensively promoted together with cultivating ethical way of thinking and acting for the sustainable well-being of the society. The actual activities of the Intergovernmental Panel of Climate Changes are not sustainable with the existing knowledge of the Earth sciences (as presented in the results of the 33rd and 34th International Geological Congresses). This knowledge should be incorporated into any further work of the IPCC. In the sphere of legislation in a large international co-operation following steps are needed: - to re-formulate the term of a "false alarm" and its legal consequences, - to demand very consequently the needed evaluation of existing risks, - to solve problems of rights of individuals and minorities in cases of the optimum use of mineral resources and of the optimum protection of the local population against emergency dangers and disasters; common good (well-being) must be considered as the priority when solving ethical dilemmas. The precaution principle should be applied in any decision making process. Earth scientists presenting their expert opinions are not exempted from civil, administrative or even criminal liabilities. Details must be established by national law and jurisprudence. The well known case of the L'Aquila earthquake (2009) should serve as a serious warning because of the proven misuse of geoethics for protecting top Italian seismologists responsible and sentenced for their inadequate superficial behaviour causing lot of human victims. Another recent scandal with the Himalayan fossil fraud will be also documented. A support is needed for any effort to analyze and to disclose the problems of the deformation of the contemporary

  18. Anisotropy of thermal infrared exitance in sunflower canopies

    NASA Technical Reports Server (NTRS)

    Tha Paw u, Kyaw; Ustin, Susan L.; Zhang, Chang-An

    1989-01-01

    Anisotropy of thermal infrared exitance above and within a relatively closed fully irrigated sunflower canopy is detailed. Azimuthal variation in thermal infrared exitance above canopies was weakly (statistically) related to solar position and was comparable to or larger than errors in satellite-based canopy estimates. Anisotropy within canopies was significantly lower and decreased with canopy closure and depth into the canopy. Measured azimuthal isotropy within canopies supports the use of this assumption in radiative transfer models. Significant differences in canopy temperature measurements were found depending upon whether the instruments were within or above the canopy. These differences could produce errors of 20-35 percent in latent energy estimates during periods of high evapotranspiration (ET) and greater errors in periods of restricted ET.

  19. Simulation of stochastic diffusion via first exit times

    NASA Astrophysics Data System (ADS)

    Lötstedt, Per; Meinecke, Lina

    2015-11-01

    In molecular biology it is of interest to simulate diffusion stochastically. In the mesoscopic model we partition a biological cell into unstructured subvolumes. In each subvolume the number of molecules is recorded at each time step and molecules can jump between neighboring subvolumes to model diffusion. The jump rates can be computed by discretizing the diffusion equation on that unstructured mesh. If the mesh is of poor quality, due to a complicated cell geometry, standard discretization methods can generate negative jump coefficients, which no longer allows the interpretation as the probability to jump between the subvolumes. We propose a method based on the mean first exit time of a molecule from a subvolume, which guarantees positive jump coefficients. Two approaches to exit times, a global and a local one, are presented and tested in simulations on meshes of different quality in two and three dimensions.

  20. Background noise measurements from jet exit vanes designed to reduced flow pulsations in an open-jet wind tunnel

    NASA Technical Reports Server (NTRS)

    Hoad, D. R.; Martin, R. M.

    1985-01-01

    Many open jet wind tunnels experience pulsations of the flow which are typically characterized by periodic low frequency velocity and pressure variations. One method of reducing these fluctuations is to install vanes around the perimeter of the jet exit to protrude into the flow. Although these vanes were shown to be effective in reducing the fluctuation content, they can also increase the test section background noise level. The results of an experimental acoustic program in the Langley 4- by 7-Meter Tunnel is presented which evaluates the effect on tunnel background noise of such modifications to the jet exit nozzle. Noise levels for the baseline tunnel configuration are compared with those for three jet exit nozzle modifications, including an enhanced noise reduction configuration that minimizes the effect of the vanes on the background noise. Although the noise levels for this modified vane configuration were comparable to baseline tunnel background noise levels in this facility, installation of these modified vanes in an acoustic tunnel may be of concern because the noise levels for the vanes could be well above background noise levels in a quiet facility.

  1. 30. VIEW OF ROOM 212 LOOKING SOUTHEAST TOWARDS EXIT DOORS. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. VIEW OF ROOM 212 LOOKING SOUTHEAST TOWARDS EXIT DOORS. EXPOSED MASONRY WALL WITH BRICK DETAILING OVER ARCHED DOORWAY IS UNPAINTED. ORIGINAL USE OF ROOM 212 WAS AS A HAYLOFT; EXTERIOR DOOR WAS USED FOR LOADING HAY. TRUSSWORK AND BEAMS ARE EXPOSED AND UNPAINTED. WALLS HAVE PAINTED WOOD PANELING, CEILING MATERIAL IS EXPOSED WOOD ROOF SHEATHING. - Presidio of San Francisco, Cavalry Stables, Cowles Street, between Lincoln Boulevard & McDowell Street, San Francisco, San Francisco County, CA

  2. Faculty Experiences Developing and Implementing Policies for Exit Exam Testing.

    PubMed

    Stonecypher, Karen; Young, Anne; Langford, Rae; Symes, Lene; Willson, Pamela

    2015-01-01

    Nursing schools use standardized exit examinations to determine student readiness for the NCLEX-RN. Yet little is known about how nursing programs develop policies for using the examinations, set benchmarks scores, and implement remediation strategies with their students. In a phenomenological study, faculty identified a testing policy process that fell into the major themes of triggers for change, policy modification, and reactions to change.

  3. Graceful exit via polymerization of pre-big-bang cosmology

    SciTech Connect

    De Risi, Giuseppe; Maartens, Roy; Singh, Parampreet

    2007-11-15

    We consider a phenomenological modification of the pre-big-bang scenario using ideas from the resolution of curvature singularities in loop quantum cosmology. We show that nonperturbative loop modifications to the dynamics, arising from the underlying polymer representation, can resolve the graceful exit problem. The curvature and the dilaton energy stay finite at all times, in both the string and Einstein frames. In the string frame, the dilaton tends to a constant value at late times after the bounce.

  4. Mitotic exit: Determining the PP2A dephosphorylation program.

    PubMed

    Pereira, Gislene; Schiebel, Elmar

    2016-08-29

    In mitotic exit, proteins that were highly phosphorylated are sequentially targeted by the phosphatase PP2A-B55, but what underlies substrate selection is unclear. In this issue, Cundell et al. (2016. J. Cell Biol http://dx.doi.org/10.1083/jcb.201606033) identify the determinants of PP2A-B55's dephosphorylation program, thereby influencing spindle disassembly, nuclear envelope reformation, and cytokinesis.

  5. First exit times of harmonically trapped particles: a didactic review

    NASA Astrophysics Data System (ADS)

    Grebenkov, Denis S.

    2015-01-01

    We revise the classical problem of characterizing first exit times of a harmonically trapped particle whose motion is described by a one- or multidimensional Ornstein-Uhlenbeck process. We start by recalling the main derivation steps of a propagator using Langevin and Fokker-Planck equations. The mean exit time, the moment-generating function and the survival probability are then expressed through confluent hypergeometric functions and thoroughly analyzed. We also present a rapidly converging series representation of confluent hypergeometric functions that is particularly well suited for numerical computation of eigenvalues and eigenfunctions of the governing Fokker-Planck operator. We discuss several applications of first exit times, such as the detection of time intervals during which motor proteins exert a constant force onto a tracer in optical tweezers single-particle tracking experiments; adhesion bond dissociation under mechanical stress; characterization of active periods of trend-following and mean-reverting strategies in algorithmic trading on stock markets; relation to the distribution of first crossing times of a moving boundary by Brownian motion. Some extensions are described, including diffusion under quadratic double-well potential and anomalous diffusion.

  6. Modeling of Fixed-Exit Porous Bleed Systems

    NASA Technical Reports Server (NTRS)

    Slater, John W.; Saunders, John D.

    2008-01-01

    A model has been developed to simulate a fixed-exit porous bleed system for supersonic inlets. The fixed-exit model allows the amount of bleed flow to vary according to local flow conditions and fixed-exit characteristics of the bleed system. This variation is important for the control of shock-wave/boundary-layer interactions within the inlet. The model computes the bleed plenum static pressure rather than requiring its specification. The model was implemented in the Wind-US computational fluid dynamics code. The model was then verified and validated against experimental data for bleed on a flat plate with and without an impinging oblique shock and for bleed in a Mach 3.0 axisymmetric, mixed-compression inlet. The model was able to accurately correlate the plenum pressures with bleed rates and simulate the effect of the bleed on the downstream boundary layer. Further, the model provided a realistic simulation of the initiation of inlet unstart. The results provide the most in-depth examination to date of bleed models for use in the simulation of supersonic inlets. The results also highlight the limitations of the models and aspects that require further research.

  7. 14 CFR 91.607 - Emergency exits for airplanes carrying passengers for hire.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES GENERAL OPERATING AND FLIGHT...; third, floor-level exits located in the forward part of the cabin; and fourth, floor-level exits...

  8. 29 CFR 1910.37 - Maintenance, safeguards, and operational features for exit routes.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... lighted so that an employee with normal vision can see along the exit route. (2) Each exit must be clearly... least five foot-candles (54 lux) by a reliable light source and be distinctive in color....

  9. The Three Dimensional Flow Field at the Exit of an Axial-Flow Turbine Rotor

    NASA Technical Reports Server (NTRS)

    Lakshminarayana, B.; Ristic, D.; Chu, S.

    1998-01-01

    A systematic and comprehensive investigation was performed to provide detailed data on the three dimensional viscous flow phenomena downstream of a modem turbine rotor and to understand the flow physics such as origin, nature, development of wakes, secondary flow, and leakage flow. The experiment was carried out in the Axial Flow Turbine Research Facility (AFTRF) at Penn State, with velocity measurements taken with a 3-D LDV System. Two radial traverses at 1% and 10% of chord downstream of the rotor have been performed to identify the three-dimensional flow features at the exit of the rotor blade row. Sufficient spatial resolution was maintained to resolve blade wake, secondary flow, and tip leakage flow. The wake deficit is found to be substantial, especially at 1% of chord downstream of the rotor. At this location, negative axial velocity occurs near the tip, suggesting flow separation in the tip clearance region. Turbulence intensities peak in the wake region, and cross- correlations are mainly associated with the velocity gradient of the wake deficit. The radial velocities, both in the wake and in the endwall region, are found to be substantial. Two counter-rotating secondary flows are identified in the blade passage, with one occupying the half span close to the casino and the other occupying the half span close to the hub. The tip leakage flow is well restricted to 10% immersion from the blade tip. There are strong vorticity distributions associated with these secondary flows and tip leakage flow. The passage averaged data are in good agreement with design values.

  10. Simultaneous Temperature and Velocity Measurements in a Large-Scale, Supersonic, Heated Jet

    NASA Technical Reports Server (NTRS)

    Danehy, P. M.; Magnotti, G.; Bivolaru, D.; Tedder, S.; Cutler, A. D.

    2008-01-01

    Two laser-based measurement techniques have been used to characterize an axisymmetric, combustion-heated supersonic jet issuing into static room air. The dual-pump coherent anti-Stokes Raman spectroscopy (CARS) measurement technique measured temperature and concentration while the interferometric Rayleigh scattering (IRS) method simultaneously measured two components of velocity. This paper reports a preliminary analysis of CARS-IRS temperature and velocity measurements from selected measurement locations. The temperature measurements show that the temperature along the jet axis remains constant while dropping off radially. The velocity measurements show that the nozzle exit velocity fluctuations are about 3% of the maximum velocity in the flow.

  11. 29 CFR 1910.36 - Design and construction requirements for exit routes.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... of exit routes necessary for your workplace, consult NFPA 101-2000, Life Safety Code. (c) Exit... way, or open space with access to the outside. (2) The street, walkway, refuge area, public way, or open space to which an exit discharge leads must be large enough to accommodate the building...

  12. 24 CFR 3280.106 - Exit facilities; egress windows and devices.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Exit facilities; egress windows and... § 3280.106 Exit facilities; egress windows and devices. (a) Every room designed expressly for sleeping purposes, unless it has an exit door (see § 3280.105), shall have at least one outside window or...

  13. 24 CFR 3280.106 - Exit facilities; egress windows and devices.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Exit facilities; egress windows and... § 3280.106 Exit facilities; egress windows and devices. (a) Every room designed expressly for sleeping purposes, unless it has an exit door (see § 3280.105), shall have at least one outside window or...

  14. State High School Exit Exams: Trends in Test Programs, Alternate Pathways, and Pass Rates

    ERIC Educational Resources Information Center

    Zhang, Ying

    2009-01-01

    The report draws from Center on Education Policy's eight-year study of high school exit exams to identify long-term trends in state policies and student performance. It highlights a growing trend among states to establish alternate pathways to graduation for students who are struggling to pass exit exams. The report also analyzes exit exam pass…

  15. 29 CFR 1910.36 - Design and construction requirements for exit routes.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... workplace, or to the exit discharge. An opening into an exit must be protected by a self-closing fire door... employee alarm system. Each fire door, including its frame and hardware, must be listed or approved by a... route must be a permanent part of the workplace. (2) An exit must be separated by fire...

  16. 29 CFR 1910.36 - Design and construction requirements for exit routes.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... exit discharge. An opening into an exit must be protected by a self-closing fire door that remains.... Each fire door, including its frame and hardware, must be listed or approved by a nationally recognized... permanent part of the workplace. (2) An exit must be separated by fire resistant materials....

  17. 29 CFR 1910.36 - Design and construction requirements for exit routes.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... workplace, or to the exit discharge. An opening into an exit must be protected by a self-closing fire door... employee alarm system. Each fire door, including its frame and hardware, must be listed or approved by a... route must be a permanent part of the workplace. (2) An exit must be separated by fire...

  18. Bypassing slip velocity: rotational and translational velocities of autophoretic colloids in terms of surface flux

    NASA Astrophysics Data System (ADS)

    Lammert, Paul E.; Crespi, Vincent H.; Nourhani, Amir

    2016-09-01

    A standard approach to propulsion velocities of autophoretic colloids with thin interaction layers uses a reciprocity relation applied to the slip velocity. But the surface flux (chemical, electrical, thermal, etc.), which is the source of the field driving the slip is often more accessible. We show how, under conditions of low Reynolds number and a field obeying the Laplace equation in the outer region, the slip velocity can be bypassed in velocity calculations. In a sense, the actual slip velocity and a normal field proportional to the flux density are equivalent for this type of calculation. Using known results for surface traction induced by rotating or translating an inert particle in a quiescent fluid, we derive simple and explicit integral formulas for translational and rotational velocities of arbitrary spheroidal and slender-body autophoretic colloids.

  19. A predictive theory of intentions to exit street-level prostitution.

    PubMed

    Cimino, Andrea N

    2012-10-01

    Street-level prostitution is notoriously difficult to escape and rarely do women exit prostitution on their first attempt or without experiencing serious negative consequences to their physical or mental health. Unfortunately, few theories exist that explain the exiting process and those that do exist are difficult to test quantitatively. This article applies the integrative model of behavioral prediction to examine intentions to exit prostitution through attitudes, norms, and self-efficacy beliefs that underlie a woman's intention to exit prostitution. Constructs unique prostitution--agency and societal context--enhance the model. This theory may explain and predict an exit from street-level prostitution.

  20. Velocity Distribution in the Boundary Layer of a Submerged Plate

    NASA Technical Reports Server (NTRS)

    Hansen, M

    1930-01-01

    This report deals with the measurement of the velocity distribution of the air in the velocity of a plate placed parallel to the air flow. The measurements took place in a small wind tunnel where the diameter of the entrance cone is 30 cm and the length of the free jet between the entrance and exit cones is about 2.5 m. The measurements were made in the free jet where the static pressure was constant, which was essential for the method of measurement used.

  1. Measurements of temperature profiles at the exit of small rockets.

    PubMed

    Griggs, M; Harshbarger, F C

    1966-02-01

    The sodium line reversal technique was used to determine the reversal temperature profile across the exit of small rockets. Measurements were made on one 73-kg thrust rocket, and two 23-kg thrust rockets with different injectors. The large rocket showed little variation of reversal temperature across the plume. However, the 23-kg rockets both showed a large decrease of reversal temperature from the axis to the edge of the plume. In addition, the sodium line reversal technique of temperature measurement was compared with an infrared technique developed in these laboratories.

  2. STS-110 crew members during emergency exit exercise during TCDT

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- STS-110 crew members practice emergency exit from the Fixed Service Structure during Terminal Countdown Demonstration Test. From left are Mission Specialists Jerry L. Ross, Lee M.E. Morin and Steven L. Smith. TCDT also includes a simulated launch countdown and is held at KSC prior to each Space Shuttle flight. Scheduled for launch April 4, the 11-day mission will feature Shuttle Atlantis docking with the International Space Station (ISS) and delivering the S0 truss, the centerpiece-segment of the primary truss structure that will eventually extend over 300 feet.

  3. Velocity field measurement of a round jet using quantitative schlieren.

    PubMed

    Iffa, Emishaw D; Aziz, A Rashid A; Malik, Aamir S

    2011-02-10

    This paper utilizes the background oriented schlieren (BOS) technique to measure the velocity field of a variable density round jet. The density field of the jet is computed based on the light deflection created during the passage of light through the understudy jet. The deflection vector estimation was carried out using phase-based optical flow algorithms. The density field is further exploited to extract the axial and radial velocity vectors with the aid of continuity and energy equations. The experiment is conducted at six different jet-exit temperature values. Additional turbulence parameters, such as velocity variance and power spectral density of the vector field, are also computed. Finally, the measured velocity parameters are compared with the hot wire anemometer measurements and their correlation is displayed.

  4. Velocity field measurement of a round jet using quantitative schlieren

    SciTech Connect

    Iffa, Emishaw D.; Aziz, A. Rashid A.; Malik, Aamir S.

    2011-02-10

    This paper utilizes the background oriented schlieren (BOS) technique to measure the velocity field of a variable density round jet. The density field of the jet is computed based on the light deflection created during the passage of light through the understudy jet. The deflection vector estimation was carried out using phase-based optical flow algorithms. The density field is further exploited to extract the axial and radial velocity vectors with the aid of continuity and energy equations. The experiment is conducted at six different jet-exit temperature values. Additional turbulence parameters, such as velocity variance and power spectral density of the vector field, are also computed. Finally, the measured velocity parameters are compared with the hot wire anemometer measurements and their correlation is displayed.

  5. Video Measurement of the Muzzle Velocity of a Potato Gun

    ERIC Educational Resources Information Center

    Jasperson, Christopher; Pollman, Anthony

    2011-01-01

    Using first principles, a theoretical equation for the maximum and actual muzzle velocities for a pneumatic cannon was recently derived. For a fixed barrel length, this equation suggests that the muzzle velocity can be enhanced by maximizing the product of the initial pressure and the volume of the propellant gas and decreasing the projectile…

  6. Steam exit flow design for aft cavities of an airfoil

    DOEpatents

    Storey, James Michael; Tesh, Stephen William

    2002-01-01

    Turbine stator vane segments have inner and outer walls with vanes extending therebetween. The inner and outer walls have impingement plates. Steam flowing into the outer wall passes through the impingement plate for impingement cooling of the outer wall surface. The spent impingement steam flows into cavities of the vane having inserts for impingement cooling the walls of the vane. The steam passes into the inner wall and through the impingement plate for impingement cooling of the inner wall surface and for return through return cavities having inserts for impingement cooling of the vane surfaces. A skirt or flange structure is provided for shielding the steam cooling impingement holes adjacent the inner wall aerofoil fillet region of the nozzle from the steam flow exiting the aft nozzle cavities. Moreover, the gap between the flash rib boss and the cavity insert is controlled to minimize the flow of post impingement cooling media therebetween. This substantially confines outflow to that exiting via the return channels, thus furthermore minimizing flow in the vicinity of the aerofoil fillet region that may adversely affect impingement cooling thereof.

  7. Mitotic Exit in the Absence of Separase Activity

    PubMed Central

    Lu, Ying

    2009-01-01

    In budding yeast, three interdigitated pathways regulate mitotic exit (ME): mitotic cyclin–cyclin-dependent kinase (Cdk) inactivation; the Cdc14 early anaphase release (FEAR) network, including a nonproteolytic function of separase (Esp1); and the mitotic exit network (MEN) driven by interaction between the spindle pole body and the bud cortex. Here, we evaluate the contributions of these pathways to ME kinetics. Reducing Cdk activity is critical for ME, and the MEN contributes strongly to ME efficiency. Esp1 contributes to ME kinetics mainly through cohesin cleavage: the Esp1 requirement can be largely bypassed if cells are provided Esp1-independent means of separating sister chromatids. In the absence of Esp1 activity, we observed only a minor ME delay consistent with a FEAR defect. Esp1 overexpression drives ME in Cdc20-depleted cells arrested in metaphase. We have found that this activity of overexpressed Esp1 depended on spindle integrity and the MEN. We defined the first quantitative measure for Cdc14 release based on colocalization with the Net1 nucleolar anchor. This measure indicates efficient Cdc14 release upon MEN activation; release driven by Esp1 in the absence of microtubules was inefficient and incapable of driving ME. We also found a novel role for the MEN: activating Cdc14 nuclear export, even in the absence of Net1. PMID:19144818

  8. Cytochrome c(2) Exit Strategy: Dissociation Studies and Evolutionary Implications.

    PubMed

    Pogorelov, Taras V; Autenrieth, Felix; Roberts, Elijah; Luthey-Schulten, Zaida A

    2007-01-25

    Small, water-soluble, type c cytochromes form a transient network connecting major bioenergetic membrane protein complexes in both photosynthesis and respiration. In the photosynthesis cycle of Rhodobacter sphaeroides, cytochrome c2 (cyt c2) docks to the reaction center (RC), undergoes electron transfer, and exits for the cytochrome bc1 complex. Translations of cyt c2 about the RC-cyt c2 docking interface and surrounding membrane reveal possible exit pathways. A pathway at a minimal elevation allowed by the architecture of the RC is analyzed using both an all-atom steered molecular dynamics simulation of the RC-cyt c2 complex and a bioinformatic analysis of the structures and sequences of cyt c. The structure-based phylogenetic analysis allows for the identification of structural elements that have evolved to satisfy the requirements of having multiple functional partners. The patterns of evolutionary variation obtained from the phylogenetic analysis of both docking partners of cyt c2 reveal conservation of key residues involved in the interaction interfaces that would be candidates for further experimental studies. Additionally, using the molecular mechanics Poisson-Boltzmann surface area method we calculate that the binding free energy of reduced cyt c2 to the RC is nearly 6 kcal/mol more favorable than with oxidized cyt c2. The redox-dependent variations lead to changes in structural flexibility, behavior of the interfacial water molecules, and eventually changes in the binding free energy of the complex. PMID:17228920

  9. Ultrasonic velocity and elastic constants of Antrim oil shale

    SciTech Connect

    Wallace, W.D.; Tepley, N.; Thomas, R.L.

    1980-01-01

    Ultrasonic velocities have been measured in 30 core samples from well 201. Both longitudinal and shear wave velocities were measured across core diameters at thirty degree intervals around the circumference in 22 of the samples. No significant angular variation of ultrasonic velocity was found in any of these. Plots of the average velocities between 1166 feet and 1486 feet are presented. In the Antrim, which lies between 1179 feet and 1422 km/s and the average shear wave velocity is 2.60 km/s. Actual velocities in the Antrim vary by + - 6% from these averages. Just above and below the Antrim the measured velocities are somewhat greater than the average Antrim values. Mass densities have also been determined for these samples and combined with the velocity data to obtain elastic constants.

  10. Competitive electricity markets, prices and generator entry and exit

    NASA Astrophysics Data System (ADS)

    Ethier, Robert George

    The electric power industry in the United States is quickly being deregulated and restructured. In the past, new electric generation capacity was added by regulated utilities to meet forecasted demand levels and maintain reserve margins. With competitive wholesale generation, investment will be the responsibility of independent private investors. Electricity prices will assume the coordinating function which has until recently been the responsibility of regulatory agencies. Competitive prices will provide the entry and exit signals for generators in the future. Competitive electricity markets have a distinctive price formation process, and thus require a specialized price model. A mean-reverting price process with stochastic jumps is proposed as an appropriate long-run price process for annual electricity prices. This price process is used to develop an analytic real options model for private investment decisions. The required recursive infinite series solutions have not been widely used for real option models. Entry thresholds and asset values for competitive wholesale electricity markets, and exit decisions for plants with significant retirement costs (i.e. nuclear power plants), are examined. The proposed model results in significantly lower trigger prices for both entry and exit decisions, and higher asset values, when compared with other standard models. The model is used to show that the incentives for retiring a nuclear plant are very sensitive to the treatment of decommissioning costs (e.g. if plant owners do not face full decommissioning costs, retirement decisions may be economically premature.) An econometric model of short-run price behavior is estimated by the method of maximum likelihood using daily electricity prices from markets in the USA and Australia. The model specifies two mean reverting price processes with stochastic Markov switching between the regimes, which allows discontinuous jumps in electricity prices. Econometric tests show that a two

  11. No Exit: An Evaluation of Measures of Physician Attrition

    PubMed Central

    Rittenhouse, Diane R; Mertz, Elizabeth; Keane, Dennis; Grumbach, Kevin

    2004-01-01

    Objective To validate physicians' self-reported intentions to leave clinical practice and the American Medical Association (AMA) Masterfile practice status variable as measures of physician attrition, and to determine predictors of intention to leave, and actual departure from, clinical practice. Data Sources Survey of specialist physicians in urban California (1998); the AMA Physician Masterfile (2001); and direct ascertainment of physician practice status (2001). Study Design Physicians' intention to leave clinical practice by 2001 (self-reported in 1998) was tested as a measure of each physician's actual practice status in 2001 (directly ascertained). Physician practice status according to the 2001 AMA Masterfile was also tested as a measure of physicians' actual practice status in 2001. Multivariate regression was used to predict both physicians' intentions to leave clinical practice and their actual departure. Data Collection/Extraction Methods AMA Masterfile data on 2001 practice status were obtained for 967 of 968 physician respondents to the 1998 survey. Actual practice status for 2001 was directly ascertained for 957. Principal Findings The sensitivity of Masterfile practice status as a measure of actual departure from clinical practice was 9.0 percent, and the positive predictive value was 52.9 percent. Allowing for a two-year reporting lag did not change this substantially. Self-reported intention to leave clinical practice had a sensitivity of 73.3 percent and a positive predictive value of 35.4 percent as a measure of actual departure from practice. The strongest predictor of both intention to leave clinical practice and actual departure from practice was older age. Physician dissatisfaction had a strong association (OR=5.6) with intention to leave clinical practice, but was not associated with actual departure from practice. Conclusions Our findings call into question the accuracy of both AMA Masterfile data and physicians' self-reported intentions to

  12. PROTOSTELLAR JETS ENCLOSED BY LOW-VELOCITY OUTFLOWS

    SciTech Connect

    Machida, Masahiro N.

    2014-11-20

    A protostellar jet and outflow are calculated for ∼270 yr following the protostar formation using a three-dimensional magnetohydrodynamics simulation, in which both the protostar and its parent cloud are spatially resolved. A high-velocity (∼100 km s{sup –1}) jet with good collimation is driven near the disk's inner edge, while a low-velocity (≲ 10 km s{sup –1}) outflow with a wide opening angle appears in the outer-disk region. The high-velocity jet propagates into the low-velocity outflow, forming a nested velocity structure in which a narrow high-velocity flow is enclosed by a wide low-velocity flow. The low-velocity outflow is in a nearly steady state, while the high-velocity jet appears intermittently. The time-variability of the jet is related to the episodic accretion from the disk onto the protostar, which is caused by gravitational instability and magnetic effects such as magnetic braking and magnetorotational instability. Although the high-velocity jet has a large kinetic energy, the mass and momentum of the jet are much smaller than those of the low-velocity outflow. A large fraction of the infalling gas is ejected by the low-velocity outflow. Thus, the low-velocity outflow actually has a more significant effect than the high-velocity jet in the very early phase of the star formation.

  13. Trajectories of Depression Symptoms among Older Youths Exiting Foster Care.

    PubMed

    Munson, Michelle R; McMillen, Curtis

    2010-12-01

    The purpose of this study was to determine the trajectories of depressive symptoms as older youths from the foster care system mature while also examining the correlates of these trajectories. Data came from a longitudinal study of 404 youths from the foster care system in Missouri, who were interviewed nine times between their 17th and 19th birthdays. Depression was assessed with the Depression Outcomes Module and the Diagnostic Interview Schedule for DSM-IV. Data best fit a model of three trajectory classes, describing young people (1) maintaining low levels of depressive symptoms (never depressed class, 78%), (2) with increasing symptoms (increasing class, 6%), and (3) with decreasing symptoms (decreasing class, 15%). The increasing depression group was mostly male youths who were working or in school; the decreasing class was mostly highly maltreated female youths exiting the foster care system from residential care, with low levels of employment, and in school. Implications for social work practice are discussed.

  14. The geometry of the ribosomal polypeptide exit tunnel.

    PubMed

    Voss, N R; Gerstein, M; Steitz, T A; Moore, P B

    2006-07-21

    The geometry of the polypeptide exit tunnel has been determined using the crystal structure of the large ribosomal subunit from Haloarcula marismortui. The tunnel is a component of a much larger, interconnected system of channels accessible to solvent that permeates the subunit and is connected to the exterior at many points. Since water and other small molecules can diffuse into and out of the tunnel along many different trajectories, the large subunit cannot be part of the seal that keeps ions from passing through the ribosome-translocon complex. The structure referred to as the tunnel is the only passage in the solvent channel system that is both large enough to accommodate nascent peptides, and that traverses the particle. For objects of that size, it is effectively an unbranched tube connecting the peptidyl transferase center of the large subunit and the site where nascent peptides emerge. At no point is the tunnel big enough to accommodate folded polypeptides larger than alpha-helices.

  15. Thermal IR exitance model of a plant canopy

    NASA Technical Reports Server (NTRS)

    Kimes, D. S.; Smith, J. A.; Link, L. E.

    1981-01-01

    A thermal IR exitance model of a plant canopy based on a mathematical abstraction of three horizontal layers of vegetation was developed. Canopy geometry within each layer is quantitatively described by the foliage and branch orientation distributions and number density. Given this geometric information for each layer and the driving meteorological variables, a system of energy budget equations was determined and solved for average layer temperatures. These estimated layer temperatures, together with the angular distributions of radiating elements, were used to calculate the emitted thermal IR radiation as a function of view angle above the canopy. The model was applied to a lodgepole pine (Pinus contorta) canopy over a diurnal cycle. Simulated vs measured radiometric average temperatures of the midcanopy layer corresponded with 2 C. Simulation results suggested that canopy geometry can significantly influence the effective radiant temperature recorded at varying sensor view angles.

  16. Focal para-hisian atrial tachycardia with dual exits

    PubMed Central

    Lawrance Jesuraj, M.; Sharada, K.; Sridevi, C.; Narasimhan, C.

    2013-01-01

    Focal atrial tachycardias (AT) in the right atrium (RA) tend to cluster around the crista terminalis, coronary sinus (CS) region, tricuspid annulus, and para-hisian region. In most cases, the AT focus can be identified by careful activation mapping, and completely eliminated by radiofrequency (RF) catheter ablation. However, RF ablation near the His bundle (HB) carries a risk of inadvertent damage to the atrioventricular (AV) conduction system. Here we describe a patient with an AT originating in the vicinity of the AV node, which was successfully ablated earlier from non-coronary aortic cusp (NCC), and recurred with an exit from para-hisian location. Respiratory excursions of the catheter were associated with migration to the area of HIs. This was successfully ablated during controlled apnoea, using 3D electroanatomic mapping. PMID:23993015

  17. An Epidemic Patchy Model with Entry-Exit Screening.

    PubMed

    Wang, Xinxin; Liu, Shengqiang; Wang, Lin; Zhang, Weiwei

    2015-07-01

    A multi-patch SEIQR epidemic model is formulated to investigate the long-term impact of entry-exit screening measures on the spread and control of infectious diseases. A threshold dynamics determined by the basic reproduction number R₀ is established: The disease can be eradicated if R₀ < 1, while the disease persists if R₀ > 1. As an application, six different screening strategies are explored to examine the impacts of screening on the control of the 2009 influenza A (H1N1) pandemic. We find that it is crucial to screen travelers from and to high-risk patches, and it is not necessary to implement screening in all connected patches, and both the dispersal rates and the successful detection rate of screening play an important role on determining an effective and practical screening strategy. PMID:25976693

  18. The entry-exit function and geometric singular perturbation theory

    NASA Astrophysics Data System (ADS)

    De Maesschalck, Peter; Schecter, Stephen

    2016-04-01

    For small ε > 0, the system x ˙ = ε, z ˙ = h (x , z , ε) z, with h (x , 0 , 0) < 0 for x < 0 and h (x , 0 , 0) > 0 for x > 0, admits solutions that approach the x-axis while x < 0 and are repelled from it when x > 0. The limiting attraction and repulsion points are given by the well-known entry-exit function. For h (x , z , ε) z replaced by h (x , z , ε)z2, we explain this phenomenon using geometric singular perturbation theory. We also show that the linear case can be reduced to the quadratic case, and we discuss the smoothness of the return map to the line z =z0, z0 > 0, in the limit ε → 0.

  19. Self-Actualization, Liberalism, and Humanistic Education.

    ERIC Educational Resources Information Center

    Porter, Charles Mack

    1979-01-01

    The relationship between personality factors and political orientation has long been of interest to psychologists. This study tests the hypothesis that there is no significant relationship between self-actualization and liberalism-conservatism. The hypothesis is supported. (Author)

  20. Effects of nozzle exit geometry and pressure ratio on plume shape for nozzles exhausting into quiescent air

    NASA Technical Reports Server (NTRS)

    Scallion, William I.

    1991-01-01

    The effects of varying the exit geometry on the plume shapes of supersonic nozzles exhausting into quiescent air at several exit-to-ambient pressure ratios are given. Four nozzles having circular throat sections and circular, elliptical and oval exit cross sections were tested and the exit plume shapes are compared at the same exit-to-ambient pressure ratios. The resulting mass flows were calculated and are also presented.

  1. Angular velocity discrimination

    NASA Technical Reports Server (NTRS)

    Kaiser, Mary K.

    1990-01-01

    Three experiments designed to investigate the ability of naive observers to discriminate rotational velocities of two simultaneously viewed objects are described. Rotations are constrained to occur about the x and y axes, resulting in linear two-dimensional image trajectories. The results indicate that observers can discriminate angular velocities with a competence near that for linear velocities. However, perceived angular rate is influenced by structural aspects of the stimuli.

  2. Fiber Optic Velocity Interferometry

    SciTech Connect

    Neyer, Barry T.

    1988-04-01

    This paper explores the use of a new velocity measurement technique that has several advantages over existing techniques. It uses an optical fiber to carry coherent light to and from a moving target. A Fabry-Perot interferometer, formed by a gradient index lens and the moving target, produces fringes with a frequency proportional to the target velocity. This technique can measure velocities up to 10 km/s, is accurate, portable, and completely noninvasive.

  3. [Prediction and influence factors of the ramp's noise of the entrance or exit of garages].

    PubMed

    Di, Guo-Qing; Zhang, Bang-Jun

    2005-09-01

    Some typical entrances/exits of the underground garages are chosen in urban residential areas. On the basis of the optimization of the positions of the noise sampling points and the groupings of the synchronous sampling points, by means of the acoustical analysis of the noise samples, the relation of the correlative factors, among the ramps' noise of the entrances or exits of the garages, the structure, grade, shape of the ramps, upgrade and downgrade, is studied. The prediction model of the ramp's noise influence of the entrance or exit of the garage is established through amending the noise influence of the entrance or exit of the even concrete road. PMID:16366500

  4. Imaging the radical channel in acetaldehyde photodissociation: Competing mechanisms at energies close to the triplet exit barrier

    SciTech Connect

    Amaral, G. A.; Arregui, A.; Rodriguez, J. D.; Banares, L.; Rubio-Lago, L.

    2010-08-14

    The photodissociation of acetaldehyde in the radical channel has been studied at wavelengths between 315 and 325 nm using the velocity-map imaging technique. Upon one-photon absorption at 315 nm, the molecule is excited to the first singlet excited state S{sub 1}, which, in turn, undergoes intersystem crossing to the first excited triplet state T{sub 1}. On the triplet surface, the molecule dissociates into CH{sub 3} and HCO radicals with large kinetic energy release (KER), in accordance with the well characterized exit barrier on T{sub 1}. However, at longer wavelengths (>320 nm), which correspond to excitation energies just below the triplet barrier, a sudden change in KER is observed. At these photolysis wavelengths, there is not enough energy to surpass the exit barrier on the triplet state, which leaves the possibility of unimolecular dissociation on S{sub 0} after internal conversion from S{sub 1}. We have characterized the fragments' KER at these wavelengths, as well as determined the energy partitioning for the radical fragments. A new accurate estimate of the barrier height on T{sub 1} is presented.

  5. Effects of forward velocity on turbulent jet mixing noise

    NASA Technical Reports Server (NTRS)

    Plumblee, H. E., Jr. (Editor)

    1976-01-01

    Flight simulation experiments were conducted in an anechoic free jet facility over a broad range of model and free jet velocities. The resulting scaling laws were in close agreement with scaling laws derived from theoretical and semiempirical considerations. Additionally, measurements of the flow structure of jets were made in a wind tunnel by using a laser velocimeter. These tests were conducted to describe the effects of velocity ratio and jet exit Mach number on the development of a jet in a coflowing stream. These turbulence measurements and a simplified Lighthill radiation model were used in predicting the variation in radiated noise at 90 deg to the jet axis with velocity ratio. Finally, the influence of forward motion on flow-acoustic interactions was examined through a reinterpretation of the 'static' numerical solutions to the Lilley equation.

  6. Three component velocity measurements in an axisymmetric jet using LDA

    NASA Technical Reports Server (NTRS)

    Kuhlman, John M.; Gross, Robert W.

    1990-01-01

    A commercial three-component laser Doppler anemometer (LDA) has been used to acquire a detailed set of three-dimensional mean and fluctuating velocity measurements in a low-speed air jet entering a stagnant ambient, over the first 15 jet exit diameters along the jet trajectory. These data are consistent with previous measurements in axisymmetric, turbulent jets. Mean velocity and Reynolds stress data approach a self-preserving behavior by x/D equal to about 15. However, the RMS turbulence fluctuations were not self-preserving at this axial location, as expected based upon previous experimental studies. These data confirm the ability to obtain reliable three-dimensional velocity data using the present three-dimensional LDA system.

  7. Stepwise shockwave velocity determinator

    NASA Technical Reports Server (NTRS)

    Roth, Timothy E.; Beeson, Harold

    1992-01-01

    To provide an uncomplicated and inexpensive method for measuring the far-field velocity of a surface shockwave produced by an explosion, a stepwise shockwave velocity determinator (SSVD) was developed. The velocity determinator is constructed of readily available materials and works on the principle of breaking discrete sensors composed of aluminum foil contacts. The discrete sensors have an average breaking threshold of approximately 7 kPa. An incremental output step of 250 mV is created with each foil contact breakage and is logged by analog-to-digital instrumentation. Velocity data obtained from the SSVD is within approximately 11 percent of the calculated surface shockwave velocity of a muzzle blast from a 30.06 rifle.

  8. Experimental investigation of an axisymmetric free jet with an initially uniform velocity profile

    NASA Technical Reports Server (NTRS)

    Labus, T. L.; Symons, E. P.

    1972-01-01

    An experimental investigation was conducted to determine the flow characteristics of a circular free helium jet having an initially uniform velocity profile. Complete velocity profiles are presented at Reynolds numbers of 1027 and 4571 at 0, 3, 6, 10, 15, and 20 nozzle diameters (where possible) from the nozzle exit. Centerline velocity decay and potential core length were obtained over a range of Reynolds numbers from 155 to 5349 at distances up to and including 25 nozzle diameters from the nozzle exit. The angles of spread associated with the diffusion of the jet downstream of the nozzle are also given. Axial jet momentum flux and entrained mass flux, at various distances downstream of the nozzle, are presented as a function of the jet Reynolds number.

  9. Realizing actual feedback control of complex network

    NASA Astrophysics Data System (ADS)

    Tu, Chengyi; Cheng, Yuhua

    2014-06-01

    In this paper, we present the concept of feedbackability and how to identify the Minimum Feedbackability Set of an arbitrary complex directed network. Furthermore, we design an estimator and a feedback controller accessing one MFS to realize actual feedback control, i.e. control the system to our desired state according to the estimated system internal state from the output of estimator. Last but not least, we perform numerical simulations of a small linear time-invariant dynamics network and a real simple food network to verify the theoretical results. The framework presented here could make an arbitrary complex directed network realize actual feedback control and deepen our understanding of complex systems.

  10. 49 CFR 238.127 - Low-location emergency exit path marking.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... the Director of the Federal Register in accordance with 5 U.S.C. 552(a) and 1 CFR Part 51. You may... 49 Transportation 4 2014-10-01 2014-10-01 false Low-location emergency exit path marking. 238.127... Requirements § 238.127 Low-location emergency exit path marking. On or after January 28, 2015,...

  11. Effects of Failing a High School Exit Exam on Course Taking, Achievement, Persistence, and Graduation

    ERIC Educational Resources Information Center

    Reardon, Sean F.; Arshan, Nicole; Atteberry, Allison; Kurlaender, Michal

    2010-01-01

    The increasing use of state-mandated public high school exit exams is one manifestation of the current movement in U.S. public schooling toward more explicit standards of instruction and accountability. Exit exam requirements implicitly argue that raising the bar for graduation creates incentives both for students to work harder in school and for…

  12. Examining the Career Paths and Transition Services of Students with Disabilities Exiting High School

    ERIC Educational Resources Information Center

    Baer, Robert M.; Flexer, Robert W.; Dennis, Lawrence

    2007-01-01

    Career paths and transition services were investigated for students with disabilities who were exiting special education for comparison with two models of transition developed by Siegel (1998) and Greene (2003). Teachers and parent-mentors from 52 local education agencies (LEAs) conducted a record review and an exit interview of 741 students with…

  13. Visual Barriers to Prevent Ambulatory ALzheimer's Patients from Exiting through an Emergency Door.

    ERIC Educational Resources Information Center

    Namazi, Kevan H.; And Others

    1989-01-01

    Conducted study on Alzheimer's unit to test seven different visual barrier conditions for reducing patient exits. Findings indicated that exiting was eliminated under two conditions. Results suggest visual agnosia, the inability to interpret what the eye sees, may be used as tool in managing wandering behavior of Alzheimer's patients. (Author/NB)

  14. A Structural Equation Model of Burnout and Job Exit among Child Protective Services Workers.

    ERIC Educational Resources Information Center

    Drake, Brett; Yadama, Gautam N.

    1996-01-01

    Uses a structural equation model to examine the three elements of the Maslach Burnout Inventory (MBI)--emotional exhaustion, depersonalization, and personal accomplishment--in relation to job exit among child protective services workers over a 15-month period. The model was supported, showing the relevance of all three MBI elements of job exit.…

  15. Drink Specials and the Intoxication Levels of Patrons Exiting College Bars

    ERIC Educational Resources Information Center

    Thombs, Dennis L.; Dodd, Virginia; Porkorny, Steven B.; Omli, Morrow R.; O'Mara, Ryan; Webb, Monica C.; Lacaci, Diana M.; Werch, Chad

    2008-01-01

    Objectives: To determine whether drink specials independently increase patrons' risk of achieving a high level of intoxication upon exiting drinking establishments. Methods: In a campus community, data were collected from exiting patrons (N=291) via sidewalk interviews and breath tests on 6 nights of 2 consecutive semesters. Results: A…

  16. 36 CFR 13.1312 - Climbing and walking on Exit Glacier.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Glacier. 13.1312 Section 13.1312 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... General Provisions § 13.1312 Climbing and walking on Exit Glacier. Except for areas designated by the Superintendent, climbing or walking on, in, or under Exit Glacier is prohibited within 1/2 mile of the...

  17. 36 CFR 13.1312 - Climbing and walking on Exit Glacier.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Glacier. 13.1312 Section 13.1312 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... General Provisions § 13.1312 Climbing and walking on Exit Glacier. Except for areas designated by the Superintendent, climbing or walking on, in, or under Exit Glacier is prohibited within 1/2 mile of the...

  18. 36 CFR 13.1312 - Climbing and walking on Exit Glacier.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Glacier. 13.1312 Section 13.1312 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... General Provisions § 13.1312 Climbing and walking on Exit Glacier. Except for areas designated by the Superintendent, climbing or walking on, in, or under Exit Glacier is prohibited within 1/2 mile of the...

  19. 36 CFR 13.1312 - Climbing and walking on Exit Glacier.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Glacier. 13.1312 Section 13.1312 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... General Provisions § 13.1312 Climbing and walking on Exit Glacier. Except for areas designated by the Superintendent, climbing or walking on, in, or under Exit Glacier is prohibited within 1/2 mile of the...

  20. 36 CFR 13.1312 - Climbing and walking on Exit Glacier.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Glacier. 13.1312 Section 13.1312 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... General Provisions § 13.1312 Climbing and walking on Exit Glacier. Except for areas designated by the Superintendent, climbing or walking on, in, or under Exit Glacier is prohibited within 1/2 mile of the...

  1. Wives' Relative Wages, Husbands' Paid Work Hours, and Wives' Labor-Force Exit

    ERIC Educational Resources Information Center

    Shafer, Emily Fitzgibbons

    2011-01-01

    Economic theories predict that women are more likely to exit the labor force if their partners' earnings are higher and if their own wage rate is lower. In this article, I use the National Longitudinal Survey of Youth (N = 2,254) and discrete-time event-history analysis to show that wives' relative wages are more predictive of their exit than are…

  2. 30 CFR 57.4530 - Exits for surface buildings and structures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Exits for surface buildings and structures. 57... Fire Prevention and Control Installation/construction/maintenance § 57.4530 Exits for surface buildings and structures. Surface buildings or structures in which persons work shall have a sufficient...

  3. Scholars Probe Diverse Effects of Exit Exams: State Graduation Tests Found to Hit Certain Groups Harder

    ERIC Educational Resources Information Center

    Viadero, Debra

    2009-01-01

    A study released last week suggesting that California's high school exit exams are affecting some student demographic groups more than others is the latest in a small spate of studies pointing to trade-offs from policies that require high school students to pass state tests to graduate. Twenty-six states have exit exams in place or will by 2012,…

  4. Tuscaloosa County School System Placement Services for Exiting Students. Final Report.

    ERIC Educational Resources Information Center

    Tuscaloosa County Board of Education, Tuscaloosa, AL.

    During the school year 1974-75, a project to place exiting students in an occupational or postsecondary program was conducted by the Tuscaloosa County School System. The project was designed to assist graduating seniors of four high schools and those exiting prior to graduation. In meeting the project goal the following activities were carried…

  5. 14 CFR 91.607 - Emergency exits for airplanes carrying passengers for hire.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Emergency exits for airplanes carrying... Emergency exits for airplanes carrying passengers for hire. (a) Notwithstanding any other provision of this chapter, no person may operate a large airplane (type certificated under the Civil Air...

  6. 14 CFR 91.607 - Emergency exits for airplanes carrying passengers for hire.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Emergency exits for airplanes carrying... Emergency exits for airplanes carrying passengers for hire. (a) Notwithstanding any other provision of this chapter, no person may operate a large airplane (type certificated under the Civil Air...

  7. 14 CFR 91.607 - Emergency exits for airplanes carrying passengers for hire.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Emergency exits for airplanes carrying... Emergency exits for airplanes carrying passengers for hire. (a) Notwithstanding any other provision of this chapter, no person may operate a large airplane (type certificated under the Civil Air...

  8. Bias and uncertainty in the absorption emission measurement of atomic sodium density in the SSME exit plane

    NASA Technical Reports Server (NTRS)

    Bauman, Leslie E.

    1990-01-01

    The measurement of atomic sodium concentration in the TTB 019 firing of April 1990 is significant in that it represents the first measurement of density at the exit plane of the space shuttle main engine. The knowledge of the sodium density, combined with the certainty that the exit plane of the plume is optically thin at the sodium D-line wavelengths, provides essential information for evaluation of diagnostic techniques using sodium atoms, such as resonant Doppler velocimetry for temperature, pressure, and velocity through high resolution fluorescent lineshape analysis. The technique used for the sodium atom line transmission (SALT) measurements is that of resonant absorption emission using a hollow cathode lamp as the reference source. Through the use of two-dimensional kinetic (TDK) predictions of temperature and density for the flight engine case and radiative transfer calculations, this line-of-sight spectrally integrated transmission indicates a sodium atom concentration, i.e., mole fraction, of 0.91e-10. The subject of this paper is the assumptions and measurement uncertainties tied into the calculation. Because of the narrow shape of the source emission, the uncertainties in the absorption profile could introduce considerable bias in the measurement. The following were investigated: (1) the inclusion of hyperfine splitting of the D-lines in the calculation; (2) the use of the flight engine predictions of plume temperature and density versus those for the large throat engine; (3) the assumption of a Gaussian, i.e., Doppler, distribution for the source radiance with a temperature of 400 K; (4) the use of atomic collisional shift and width values for the work by Jongerius; and (5) a Doppler shift for a 7 degree outward velocity vector at the plume edge. Also included in the study was the bias introduced by an uncertainty in the measurement of the D1/D2 line ratio in the source.

  9. Core compressor exit stage study. 1: Aerodynamic and mechanical design

    NASA Technical Reports Server (NTRS)

    Burdsall, E. A.; Canal, E., Jr.; Lyons, K. A.

    1979-01-01

    The effect of aspect ratio on the performance of core compressor exit stages was demonstrated using two three stage, highly loaded, core compressors. Aspect ratio was identified as having a strong influence on compressors endwall loss. Both compressors simulated the last three stages of an advanced eight stage core compressor and were designed with the same 0.915 hub/tip ratio, 4.30 kg/sec (9.47 1bm/sec) inlet corrected flow, and 167 m/sec (547 ft/sec) corrected mean wheel speed. The first compressor had an aspect ratio of 0.81 and an overall pressure ratio of 1.357 at a design adiabatic efficiency of 88.3% with an average diffusion factor or 0.529. The aspect ratio of the second compressor was 1.22 with an overall pressure ratio of 1.324 at a design adiabatic efficiency of 88.7% with an average diffusion factor of 0.491.

  10. Cdc28 Activates Exit from Mitosis in Budding Yeast

    PubMed Central

    Rudner, Adam D.; Hardwick, Kevin G.; Murray, Andrew W.

    2000-01-01

    The activity of the cyclin-dependent kinase 1 (Cdk1), Cdc28, inhibits the transition from anaphase to G1 in budding yeast. CDC28-T18V, Y19F (CDC28-VF), a mutant that lacks inhibitory phosphorylation sites, delays the exit from mitosis and is hypersensitive to perturbations that arrest cells in mitosis. Surprisingly, this behavior is not due to a lack of inhibitory phosphorylation or increased kinase activity, but reflects reduced activity of the anaphase-promoting complex (APC), a defect shared with other mutants that lower Cdc28/Clb activity in mitosis. CDC28-VF has reduced Cdc20- dependent APC activity in mitosis, but normal Hct1- dependent APC activity in the G1 phase of the cell cycle. The defect in Cdc20-dependent APC activity in CDC28-VF correlates with reduced association of Cdc20 with the APC. The defects of CDC28-VF suggest that Cdc28 activity is required to induce the metaphase to anaphase transition and initiate the transition from anaphase to G1 in budding yeast. PMID:10871278

  11. Compact Fixed-exit UHV DCM for XAFS

    SciTech Connect

    Rickers, K.; Brueggmann, U.; Drube, W.; Herrmann, M.; Heuer, J.; Welter, E.; Schulte-Schrepping, H.; Schulz-Ritter, H.

    2007-01-19

    A double-crystal, UHV-compatible monochromator for XAFS applications at bending magnet beamlines has been designed. It uses two crystal sets, Si(111) and (311), on a common central rotation axis driven by an ex-vacuo goniometer. All mechanical and electrical components are mounted on a 400 mm UHV flange which is attached to a compact vacuum chamber. The first crystals are water cooled using connector- and bellowless tubing through the fluidic sealed feedthrough of the central rotation. The first crystal set is mounted off-axis and can be translated vertically to keep the fixed exit condition. The second crystal set uses small crystals of the same size as the first. In order to accept the reflected beam of the first crystal at small Bragg angles, it is tangentially translated along the beam. The angle can be varied from 5 deg. to 55.5 deg. resulting in a total energy range 2.4 - 43.4 keV for Si(111)/(311). Crystal sets are interchangeable by translating the vacuum chamber. Angle encoding is achieved by a Renishaw incremental optical encoder in vacuo.

  12. Loop corrections and graceful exit in string cosmology

    NASA Astrophysics Data System (ADS)

    Foffa, Stefano; Maggiore, Michele; Sturani, Riccardo

    1999-07-01

    We examine the effect of perturbative string loops on the cosmological pre-big-bang evolution. We study loop corrections derived from heterotic string theory compactified on a ZN orbifold and we consider the effect of the all-order loop corrections to the Kähler potential and of the corrections to gravitational couplings, including both threshold corrections and corrections due to the mixed Kähler-gravitational anomaly. We find that string loops can drive the evolution into the region of the parameter space where a graceful exit is in principle possible, and we find solutions that, in the string frame, connect smoothly the superinflationary pre-big-bang evolution to a phase where the curvature and the derivative of the dilaton are decreasing. We also find that at a critical coupling the loop corrections to the Kähler potential induce a ghost-like instability, i.e. the kinetic term of the dilaton vanishes. This is similar to what happens in Seiberg-Witten theory and signals the transition to a new regime where the light modes in the effective action are different and are related to the original ones by S-duality. In a string context, this means that we enter a D-brane dominated phase.

  13. Thermal radiant exitance model performance: Soils and forests

    SciTech Connect

    Balick, L.K.; Smith, J.A.

    1995-12-31

    Models of surface temperatures of two land surface types based on their energy budgets were developed to simulate the effects of environmental factors on thermal radiant exitance. The performance of these models is examined in detail. One model solves the non-linear differential equation for heat diffusion in solids using a set of submodels for surface energy budget components. The model performance is examined under three desert conditions thought to be a strong test of the submodels. The accuracy of the temperature predictions and submodels is described. The accuracy of the model is generally good but some discrepancies between some of the submodels and measurements are noted. The sensitivity of the submodels is examined and is seen to be strongly controlled by interaction and feedback among energy components that are a function of surface temperature. The second model simulates vegetation canopies with detailed effects of surface geometry on radiant transfer in the canopy. Foliage solar absorption coefficients are calculated using a radiosity approach for a three layer canopy and long wave fluxes are modeled using a view factor matrix. Sensible and latent heat transfer through the canopy are also simulated using, nearby meteorological data but heat storage in the canopy is not included. Simulations for a coniferous forest canopy are presented and the sensitivity of the model to environmental inputs is discussed.

  14. Exposure to violence in adolescence and precocious role exits.

    PubMed

    Haynie, Dana L; Petts, Richard J; Maimon, David; Piquero, Alex R

    2009-03-01

    Exposure to violence is a serious public health concern that compromises adolescents by affecting their behavior and psychological well-being. The current study advances knowledge about the consequences of exposure to violence in adolescence by applying a life course perspective to evaluate the developmental implications of adolescents' exposure to violence. In particular, drawing on a sample of 11,949 school-aged adolescents in the U.S., we examine whether exposure to violence in adolescence is associated with precocious role exits that some adolescents experience. Exposure to violence is conceptualized as including both direct (i.e., experiencing physical victimization) and indirect exposure (i.e., witnessing others' victimization). Three types of direct exposure to violence are examined: street, intimate partner, and family victimization, as well as four types of indirect exposure including: street, peer, and school violence as well as exposure to family/friend suicide. Using three waves of longitudinal data from the Add Health Study, we find that exposure to violence is associated with greater risks of running away from home, dropping out of high school, having a child, attempting suicide, and coming into contact with the criminal justice system in later adolescence. In addition, risks depend upon the relational context in which the exposure to violence occurred, risks increase with greater exposure to violence, and risks are, for the most part, highest for those youth exposed to both indirect and direct violence in adolescence. PMID:19636744

  15. Folding and escape of nascent proteins at ribosomal exit tunnel

    NASA Astrophysics Data System (ADS)

    Bui, Phuong Thuy; Hoang, Trinh Xuan

    2016-03-01

    We investigate the interplay between post-translational folding and escape of two small single-domain proteins at the ribosomal exit tunnel by using Langevin dynamics with coarse-grained models. It is shown that at temperatures lower or near the temperature of the fastest folding, folding proceeds concomitantly with the escape process, resulting in vectorial folding and enhancement of foldability of nascent proteins. The concomitance between the two processes, however, deteriorates as temperature increases. Our folding simulations as well as free energy calculation by using umbrella sampling show that, at low temperatures, folding at the tunnel follows one or two specific pathways without kinetic traps. It is shown that the escape time can be mapped to a one-dimensional diffusion model with two different regimes for temperatures above and below the folding transition temperature. Attractive interactions between amino acids and attractive sites on the tunnel wall lead to a free energy barrier along the escape route of the protein. It is suggested that this barrier slows down the escape process and consequently promotes correct folding of the released nascent protein.

  16. Phenotypic Diversity as a Mechanism to Exit Cellular Dormancy

    PubMed Central

    Sturm, Alexander; Dworkin, Jonathan

    2016-01-01

    SUMMARY Microorganisms can facilitate their survival in stressful environments by entering a state of metabolic inactivity or dormancy [1]. However, this state impairs the function of the very sensory systems necessary to detect favorable growth conditions. Thus, how can a metabolically quiescent cell accurately monitor environmental conditions in order to best decide when to exit dormancy? One strategy employed by microbes to deal with changing environments is the generation of phenotypes that may be less well adapted to a current condition but might confer an advantage in the future [2, 3]. This bet-hedging depends on phenotypic diversity in the population [4], which itself can derive from naturally occurring stochastic differences in gene expression [5, 6]. In the case of metabolic dormancy, a bet-hedging strategy that has been proposed is the “scout model” where cells comprising a fraction of the dormant population reinitiate growth stochastically, independent of environmental cues [7, 8]. Here, we provide experimental evidence that such a mechanism exists in dormant spores produced by the ubiquitous soil bacterium Bacillus subtilis. We observe that these spores reinitiate growth at a low but measureable frequency even in the absence of an inducing signal. This phenomenon is the result of phenotypic variation in the propensity of individual spores to reinitiate growth spontaneously. Since this bet-hedging mechanism produces individuals that will either grow under favorable conditions or die under unfavorable conditions, a population can properly respond to environmental changes despite the impaired sensory ability of individual cells. PMID:26279233

  17. The effect of non-zero radial velocity on the impulse and circulation of starting jets

    NASA Astrophysics Data System (ADS)

    Krieg, Michael; Mohseni, Kamran

    2011-11-01

    Vortex ring formation dynamics are generally studied using two basic types of vortex generators. Piston cylinder vortex generators eject fluid through a long tube which ensures a purely axial jet; whereas, vortex ring generators which expel fluid through a flat plate with a circular orifice produce 2-D jets (non-zero radial velocity). At the nozzle exit plane of the orifice type vortex generator the radial component of velocity is linearly proportional to the radial distance from the axis of symmetry, reaching a maximum at the edge of the orifice with a magnitude around 10 % of the piston velocity (the ratio of the volume flux and the nozzle area). As the jet advances downstream the radial velocity quickly dissipates, and becomes purely axial less than a diameter away from the nozzle exit plane. The radial velocity gradient in the axial direction plays a key role in the rate at which circulation and impulse are ejected from the vortex generator. Though the radial component of velocity is small compared to the axial velocity, it has a significant effect on both the circulation and impulse of the starting jet because of this gradient. The extent of circulation and impulse enhancement is investigated through experimental DPIV data showing that the orifice device produces nearly double both circulation and energy (with identical piston velocity and stroke ratios).

  18. Velocity reversals and sediment sorting in pools and riffles controlled by channel constrictions

    USGS Publications Warehouse

    Thompson, D.M.; Wohl, E.E.; Jarrett, R.D.

    1999-01-01

    Keller [Keller, E.A., 1971. Areal sorting of bed-load material; the hypothesis of velocity reversal. Geological Society of America Bulletin 82, 753-756] hypothesized that at high flow, near-bed velocities in pools exceed velocities in riffles and create pool scour. Pools, however, typically have larger cross-sectional areas of flow at bankfull discharge. This condition raises an inconsistency with Keller's velocity reversal hypothesis and the one-dimensional continuity of mass equation. To address this problem, a model of pool maintenance and sediment sorting is proposed that relies on constriction of flow by recirculating eddies and flow divergence over the exit-slopes of pools. According to the model, a narrow zone of high velocity occurs in the center of pools, creating scour. Along the downstream end of pools, an uphill climb of particles up the pool exit-slope promotes sediment deposition. The model is tested with field and flume measurements of velocity, water-surface elevation, and size of bed sediments in recirculating-eddy influenced pools. Local reversals of the water-surface gradient were measured in the field and a velocity reversal was created in the flume. The reversals that were measured indicate higher gradients of the water surface over the upstream portions of pools and higher velocities in pools at high flow. The distribution of bed sediments collected in the field also support the proposed model of pool maintenance.

  19. Aggregating job exit statuses of a plurality of compute nodes executing a parallel application

    SciTech Connect

    Aho, Michael E.; Attinella, John E.; Gooding, Thomas M.; Mundy, Michael B.

    2015-07-21

    Aggregating job exit statuses of a plurality of compute nodes executing a parallel application, including: identifying a subset of compute nodes in the parallel computer to execute the parallel application; selecting one compute node in the subset of compute nodes in the parallel computer as a job leader compute node; initiating execution of the parallel application on the subset of compute nodes; receiving an exit status from each compute node in the subset of compute nodes, where the exit status for each compute node includes information describing execution of some portion of the parallel application by the compute node; aggregating each exit status from each compute node in the subset of compute nodes; and sending an aggregated exit status for the subset of compute nodes in the parallel computer.

  20. Developing Human Resources through Actualizing Human Potential

    ERIC Educational Resources Information Center

    Clarken, Rodney H.

    2012-01-01

    The key to human resource development is in actualizing individual and collective thinking, feeling and choosing potentials related to our minds, hearts and wills respectively. These capacities and faculties must be balanced and regulated according to the standards of truth, love and justice for individual, community and institutional development,…

  1. [Actual diet of patients with gastrointestinal diseases].

    PubMed

    Loranskaia, T I; Shakhovskaia, A K; Pavliuchkova, M S

    2000-01-01

    The study of actual nutrition of patients with erosive-ulcerative lesions in the gastroduodenal zone and of patients with operated ulcer has revealed defects in intake of essential nutrients by these patients: overeating of animal fat and refined carbohydrates, deficiency of oil, vitamins A, B2, C, D and food fibers.

  2. Humanistic Education and Self-Actualization Theory.

    ERIC Educational Resources Information Center

    Farmer, Rod

    1984-01-01

    Stresses the need for theoretical justification for the development of humanistic education programs in today's schools. Explores Abraham Maslow's hierarchy of needs and theory of self-actualization. Argues that Maslow's theory may be the best available for educators concerned with educating the whole child. (JHZ)

  3. Group Counseling for Self-Actualization.

    ERIC Educational Resources Information Center

    Streich, William H.; Keeler, Douglas J.

    Self-concept, creativity, growth orientation, an integrated value system, and receptiveness to new experiences are considered to be crucial variables to the self-actualization process. A regular, year-long group counseling program was conducted with 85 randomly selected gifted secondary students in the Farmington, Connecticut Public Schools. A…

  4. Teenagers' Perceived and Actual Probabilities of Pregnancy.

    ERIC Educational Resources Information Center

    Namerow, Pearila Brickner; And Others

    1987-01-01

    Explored adolescent females' (N=425) actual and perceived probabilities of pregnancy. Subjects estimated their likelihood of becoming pregnant the last time they had intercourse, and indicated the dates of last intercourse and last menstrual period. Found that the distributions of perceived probability of pregnancy were nearly identical for both…

  5. Velocity of Sound

    ERIC Educational Resources Information Center

    Gillespie, A.

    1975-01-01

    Describes a method for the determination of the velocity of sound using a dual oscilloscope on which is displayed the sinusoidal input into a loudspeaker and the signal picked up by a microphone. (GS)

  6. Near wake velocity profiles

    SciTech Connect

    Porterio, J.L.F.; Page, R.H.; Przirembel, C.E.G.

    1984-02-01

    The development of the wake velocity profile behind a cylindrical blunt based body aligned with a subsonic uniform stream was experimentally investigated as a function of the momentum thickness of the approaching boundary layer and the transfer of mass into the recirculating region. Tests were conducted at M = 0.11 in an interference-free wind tunnel utilizing an upstream support system. Results indicate that the width of the wake increases with the thickness of the boundary layer while the velocity at the centerline decreases. Near wake mass transfer was found to alter centerline velocities while the width of the wake was not significantly altered. Wake centerline velocity development as a function of boundary layer thickness is presented for distances up to three diameters from the base.

  7. High Velocity Gas Gun

    NASA Technical Reports Server (NTRS)

    1988-01-01

    A video tape related to orbital debris research is presented. The video tape covers the process of loading a High Velocity Gas Gun and firing it into a mounted metal plate. The process is then repeated in slow motion.

  8. Nonintrusive Temperature and Velocity Measurements in a Hypersonic Nozzle Flow

    NASA Technical Reports Server (NTRS)

    OByrne, S.; Danehy, P. M.; Houwing, A. F. P.

    2002-01-01

    Distributions of nitric oxide vibrational temperature, rotational temperature and velocity have been measured in the hypersonic freestream at the exit of a conical nozzle, using planar laser-induced fluorescence. Particular attention has been devoted to reducing the major sources of systematic error that can affect fluorescence tempera- ture measurements, including beam attenuation, transition saturation effects, laser mode fluctuations and transition choice. Visualization experiments have been performed to improve the uniformity of the nozzle flow. Comparisons of measured quantities with a simple one-dimensional computation are made, showing good agreement between measurements and theory given the uncertainty of the nozzle reservoir conditions and the vibrational relaxation rate.

  9. Determination of plasma velocity from light fluctuations in a cutting torch

    SciTech Connect

    Prevosto, L.; Mancinelli, B.; Kelly, H.

    2009-09-01

    Measurements of plasma velocities in a 30 A high energy density cutting torch are reported. The velocity diagnostic is based on the analysis of the light fluctuations emitted by the arc which are assumed to propagate with the flow velocity. These light fluctuations originate from plasma temperature and plasma density fluctuations mainly due to hydrodynamic instabilities. Fast photodiodes are employed as the light sensors. The arc core velocity was obtained from spectrally filtered light fluctuations measurements using a band-pass filter to detect light emission fluctuations emitted only from the arc axis. Maximum plasma jet velocities of 5000 m s{sup -1} close to the nozzle exit and about 2000 m s{sup -1} close to the anode were found. The obtained velocity values are in good agreement with those values predicted by a numerical code for a similar torch to that employed in this work.

  10. Mean exit time and survival probability within the CTRW formalism

    NASA Astrophysics Data System (ADS)

    Montero, M.; Masoliver, J.

    2007-05-01

    An intense research on financial market microstructure is presently in progress. Continuous time random walks (CTRWs) are general models capable to capture the small-scale properties that high frequency data series show. The use of CTRW models in the analysis of financial problems is quite recent and their potentials have not been fully developed. Here we present two (closely related) applications of great interest in risk control. In the first place, we will review the problem of modelling the behaviour of the mean exit time (MET) of a process out of a given region of fixed size. The surveyed stochastic processes are the cumulative returns of asset prices. The link between the value of the MET and the timescale of the market fluctuations of a certain degree is crystal clear. In this sense, MET value may help, for instance, in deciding the optimal time horizon for the investment. The MET is, however, one among the statistics of a distribution of bigger interest: the survival probability (SP), the likelihood that after some lapse of time a process remains inside the given region without having crossed its boundaries. The final part of the manuscript is devoted to the study of this quantity. Note that the use of SPs may outperform the standard “Value at Risk" (VaR) method for two reasons: we can consider other market dynamics than the limited Wiener process and, even in this case, a risk level derived from the SP will ensure (within the desired quintile) that the quoted value of the portfolio will not leave the safety zone. We present some preliminary theoretical and applied results concerning this topic.

  11. Exit Survey of Senior Residents: Cost Conscious but Uninformed.

    PubMed

    Long, Theodore; Silvestri, Mark T; Dashevsky, Meir; Halim, Andrea; Fogerty, Robert L

    2016-05-01

    Background Cost awareness, to ensure physician stewardship of limited resources, is increasingly recognized as an important skill for physicians. The Accreditation Council for Graduate Medical Education has made cost awareness part of systems-based practice, a core competency of resident education. However, little is known about resident cost awareness. Objective We sought to assess senior resident self-perceived cost awareness and cost knowledge. Methods In March 2014, we conducted a cross-sectional survey of all emergency medicine, internal medicine, obstetrics and gynecology, orthopaedic surgery pediatrics, and medicine-pediatrics residents in their final year at Yale-New Haven Hospital. The survey examined attitudes toward health care costs and residents' estimates of order prices. We considered resident price estimates to be accurate if they were between 50% and 200% of the Connecticut-specific Medicare price. Results We sent the survey to 84 residents and received 47 completed surveys (56% response rate). Although more than 95% (45 of 47) felt that containing costs is the responsibility of every clinician, and 49% (23 of 47) agreed that cost influenced their decision when ordering, only 4% (2 of 47) agreed that they knew the cost of tests being ordered. No residents accurately estimated the price of a complete blood count with differential, and only 2.1% (1 of 47) were accurate for a basic metabolic panel. The overall accuracy of all resident responses was 25%. Conclusions In our study, many trainees exit residency with self-identified deficiencies in knowledge about costs. The findings show the need for educational approaches to improve cost awareness among trainees. PMID:27168897

  12. Sensitivity to Auditory Velocity Contrast.

    PubMed

    Locke, Shannon M; Leung, Johahn; Carlile, Simon

    2016-06-13

    A natural auditory scene often contains sound moving at varying velocities. Using a velocity contrast paradigm, we compared sensitivity to velocity changes between continuous and discontinuous trajectories. Subjects compared the velocities of two stimulus intervals that moved along a single trajectory, with and without a 1 second inter stimulus interval (ISI). We found thresholds were threefold larger for velocity increases in the instantaneous velocity change condition, as compared to instantaneous velocity decreases or thresholds for the delayed velocity transition condition. This result cannot be explained by the current static "snapshot" model of auditory motion perception and suggest a continuous process where the percept of velocity is influenced by previous history of stimulation.

  13. Evacuation dynamic and exit optimization of a supermarket based on particle swarm optimization

    NASA Astrophysics Data System (ADS)

    Li, Lin; Yu, Zhonghai; Chen, Yang

    2014-12-01

    A modified particle swarm optimization algorithm is proposed in this paper to investigate the dynamic of pedestrian evacuation from a fire in a public building-a supermarket with multiple exits and configurations of counters. Two distinctive evacuation behaviours featured by the shortest-path strategy and the following-up strategy are simulated in the model, accounting for different categories of age and sex of the pedestrians along with the impact of the fire, including gases, heat and smoke. To examine the relationship among the progress of the overall evacuation and the layout and configuration of the site, a series of simulations are conducted in various settings: without a fire and with a fire at different locations. Those experiments reveal a general pattern of two-phase evacuation, i.e., a steep section and a flat section, in addition to the impact of the presence of multiple exits on the evacuation along with the geographic locations of the exits. For the study site, our simulations indicated the deficiency of the configuration and the current layout of this site in the process of evacuation and verified the availability of proposed solutions to resolve the deficiency. More specifically, for improvement of the effectiveness of the evacuation from the site, adding an exit between Exit 6 and Exit 7 and expanding the corridor at the right side of Exit 7 would significantly reduce the evacuation time.

  14. Reproducing Actual Morphology of Planetary Lava Flows

    NASA Astrophysics Data System (ADS)

    Miyamoto, H.; Sasaki, S.

    1996-03-01

    Assuming that lava flows behave as non-isothermal laminar Bingham fluids, we developed a numerical code of lava flows. We take the self gravity effects and cooling mechanisms into account. The calculation method is a kind of cellular automata using a reduced random space method, which can eliminate the mesh shape dependence. We can calculate large scale lava flows precisely without numerical instability and reproduce morphology of actual lava flows.

  15. The Actual Apollo 13 Prime Crew

    NASA Technical Reports Server (NTRS)

    1970-01-01

    The actual Apollo 13 lunar landing mission prime crew from left to right are: Commander, James A. Lovell Jr., Command Module pilot, John L. Swigert Jr.and Lunar Module pilot, Fred W. Haise Jr. The original Command Module pilot for this mission was Thomas 'Ken' Mattingly Jr. but due to exposure to German measles he was replaced by his backup, Command Module pilot, John L. 'Jack' Swigert Jr.

  16. Transgenic C. elegans dauer larvae expressing hookworm phospho null DAF-16/FoxO exit dauer.

    PubMed

    Gelmedin, Verena; Brodigan, Thomas; Gao, Xin; Krause, Michael; Wang, Zhu; Hawdon, John M

    2011-01-01

    Parasitic hookworms and the free-living model nematode Caenorhabtidis elegans share a developmental arrested stage, called the dauer stage in C. elegans and the infective third-stage larva (L3) in hookworms. One of the key transcription factors that regulate entrance to and exit from developmental arrest is the forkhead transcription factor DAF-16/FoxO. During the dauer stage, DAF-16 is activated and localized in the nucleus. DAF-16 is negatively regulated by phosphorylation by the upstream kinase AKT, which causes DAF-16 to localize out of the nucleus and the worm to exit from dauer. DAF-16 is conserved in hookworms, and hypothesized to control recovery from L3 arrest during infection. Lacking reverse genetic techniques for use in hookworms, we used C. elegans complementation assays to investigate the function of Ancylostoma caninum DAF-16 during entrance and exit from L3 developmental arrest. We performed dauer switching assays and observed the restoration of the dauer phenotype when Ac-DAF-16 was expressed in temperature-sensitive dauer defective C. elegans daf-2(e1370);daf-16(mu86) mutants. AKT phosphorylation site mutants of Ac-DAF-16 were also able to restore the dauer phenotype, but surprisingly allowed dauer exit when temperatures were lowered. We used fluorescence microscopy to localize DAF-16 during dauer and exit from dauer in C. elegans DAF-16 mutant worms expressing Ac-DAF-16, and found that Ac-DAF-16 exited the nucleus during dauer exit. Surprisingly, Ac-DAF-16 with mutated AKT phosphorylation sites also exited the nucleus during dauer exit. Our results suggest that another mechanism may be involved in the regulation DAF-16 nuclear localization during recovery from developmental arrest.

  17. Velocities in Solar Pores

    NASA Astrophysics Data System (ADS)

    Balasubramaniam, K. S.; Keil, S. L.; Smaldone, L. A.

    1996-05-01

    We investigate the three dimensional structure of solar pores and their surroundings using high spatial and spectral resolution data. We present evidence that surface velocities decrease around pores with a corresponding increase in the line-of-sight (LOS) velocities. LOS velocities in pores increase with the strength of the magnetic field. Surface velocities show convergence toward a weak downflow which appear to trace boundaries resembling meso-granular and super granular flows. The observed magnetic fields in the pores appear near these boundaries. We analyze the vertical velocity structure in pores and show that they generally have downflows decreasing exponentially with height, with a scale height of about 90 km. Evidence is also presented for the expanding nature of flux tubes. Finally we describe a phenomenological model for pores. This work was supported by AFOSR Task 2311G3. LAS was partially supported by the Progetto Nazionale Astrofisica e Fisica Cosmica of MURST and Scambi Internazionali of the Universita degli Studi di Napoli Frederico II. National Solar Observatory, NOAO, is operated for the National Science Foundation by AURA, Inc.

  18. Market entry and exit by biotech and device companies funded by venture capital.

    PubMed

    Burns, Lawton R; Housman, Michael G; Robinson, Charles A

    2009-01-01

    Start-up companies in the biotechnology and medical device sectors are important sources of health care innovation. This paper describes the role of venture capital in supporting these companies and charts the growth in venture capital financial support. The paper then uses longitudinal data to describe market entry and exit by these companies. Similar factors are associated with entry and exit in the two sectors. Entries and exits in one sector also appear to influence entry in the other. These findings have important implications for developing innovative technologies and ensuring competitive markets in the life sciences.

  19. Development of an Energetic X-Ray Imaging Telescope Experiment (EXITE) and Associated Balloon Gondola System

    NASA Technical Reports Server (NTRS)

    1997-01-01

    This is the Final Report for grant NAGW-624, which was our original grant to develop the Energetic X- ray Imaging Telescope Experiment (EXITE) and Associated Balloon Gondola. The EXITE grant was changed over to a new grant (from GSFC), NAG5-5103, beginning in FY97 and is currently very much continuing under that grant. The Final Report presented here then covers the EXITE development under the original grant, which in fact continued (with a 1 year no-cost extension) through December 31, 1997.

  20. Static performance of an axisymmetric nozzle with post-exit vanes for multiaxis thrust vectoring

    NASA Technical Reports Server (NTRS)

    Berrier, Bobby L.; Mason, Mary L.

    1988-01-01

    An investigation was conducted in the static test facility of the Langley 16-Foot Transonic Tunnel to determine the flow-turning capability and the nozzle internal performance of an axisymmetric convergent-divergent nozzle with post-exit vanes installed for multiaxis thrust vectoring. The effects of vane curvature, vane location relative to the nozzle exit, number of vanes, and vane deflection angle were determined. A comparison of the post-exit-vane thrust-vectoring concept with other thrust-vectoring concepts is provided. All tests were conducted with no external flow, and nozzle pressure ratio was varied from 1.6 to 6.0.

  1. Jet engine nozzle exit configurations, including projections oriented relative to pylons, and associated systems and methods

    NASA Technical Reports Server (NTRS)

    Mengle, Vinod G. (Inventor); Thomas, Russell H. (Inventor)

    2012-01-01

    Nozzle exit configurations and associated systems and methods are disclosed. An aircraft system in accordance with one embodiment includes a jet engine exhaust nozzle having an internal flow surface and an exit aperture, with the exit aperture having a perimeter that includes multiple projections extending in an aft direction. Aft portions of individual neighboring projections are spaced apart from each other by a gap, and a geometric feature of the multiple can change in a monotonic manner along at least a portion of the perimeter. Projections near a support pylon and/or associated heat shield can have particular configurations, including greater flow immersion than other projections.

  2. Optimum Design of a Passive Suspension System of a Vehicle Subjected to Actual Random Road Excitations

    NASA Astrophysics Data System (ADS)

    Tamboli, J. A.; Joshi, S. G.

    1999-01-01

    Vehicles are subjected to random excitation due to road unevenness and variable velocity. In most research work reported earlier, the response analysis for Mean Square Acceleration Response (MSAR) has been carried out by considering the power spectral density (PSD) of the road excitation as white noise, and the velocity of the vehicle as constant. However, in the present paper the PSD of the actual road excitation has been found to follow an approximately exponentially decreasing curve. Also the change in vehicle velocity has a significant effect on the values of Root Mean Square Acceleration Response (RMSAR). Therefore, in this work, the RMSAR of a vehicle dynamic system subjected to actual random road excitations is obtained so as to account for the effect of the actual PSD of road excitation and the frequent changes in vehicle velocity. The RMSAR of the vehicle is calculated for actual field excitation using the Fast Fourier Transformation (FFT) technique to obtain the PSD, by recording observations at the rear wheel. The effect of time lag due to wheelbase on the RMSAR of the vehicle is studied. For this purpose, a new ratio α(τ) has been introduced. The relationship between α(τ) and the autocorrelation has been formulated. This ratio is useful for considering the effect of time lag due to wheelbase on RMSAR. Similarly, the effect of vehicle velocity on the RMSAR is obtained.Further, from a ride comfort point of view, the values of the design variables like spring stiffness and viscous damping coefficient of the front and rear suspensions have been obtained, by minimising the RMSAR using the desired boundary values of the vertical RMSAR as specified in the chart of ISO 2631, 1985(E) [1].

  3. Non-intrusive Space Shuttle Main Engine nozzle exit diagnostics

    NASA Technical Reports Server (NTRS)

    Shirley, John A.; Boedeker, Laurence R.

    1988-01-01

    The results of a conceptual design study on the feasibility of nonintrusive optical diagnostics have shown that UV laser-excited Raman scattering can furnish reliable and accurate temperature and multiple-species data for the Space Shuttle Main Engine's exhaust flow. Enhanced OH flow tagging by UV photodissociation of H2O was used in velocity measurements; a time-delayed pulsed dye laser beam at 308 nm excites fluorescence from OH, and the location of the convected enhanced OH zone is measured with an optical multichannel detector.

  4. Quantitative velocity modulation spectroscopy

    NASA Astrophysics Data System (ADS)

    Hodges, James N.; McCall, Benjamin J.

    2016-05-01

    Velocity Modulation Spectroscopy (VMS) is arguably the most important development in the 20th century for spectroscopic study of molecular ions. For decades, interpretation of VMS lineshapes has presented challenges due to the intrinsic covariance of fit parameters including velocity modulation amplitude, linewidth, and intensity. This limitation has stifled the growth of this technique into the quantitative realm. In this work, we show that subtle changes in the lineshape can be used to help address this complexity. This allows for determination of the linewidth, intensity relative to other transitions, velocity modulation amplitude, and electric field strength in the positive column of a glow discharge. Additionally, we explain the large homogeneous component of the linewidth that has been previously described. Using this component, the ion mobility can be determined.

  5. High-School Exit Examinations and the Schooling Decisions of Teenagers: Evidence from Regression-Discontinuity Approaches

    ERIC Educational Resources Information Center

    Papay, John P.; Murnane, Richard J.; Willett, John B.

    2014-01-01

    We examine whether barely failing one or more state-mandated high school exit examinations in Massachusetts affects the probability that students enroll in college. We extend the exit examination literature in two ways. First, we explore longer term effects of failing these tests. We find that barely failing an exit examination, for students on…

  6. Cirrus Crystal Terminal Velocities.

    NASA Astrophysics Data System (ADS)

    Heymsfield, Andrew J.; Iaquinta, Jean

    2000-04-01

    Cirrus crystal terminal velocities are of primary importance in determining the rate of transport of condensate from upper- to middle-tropospheric levels and profoundly influence the earth's radiation balance through their effect on the rate of buildup or decay of cirrus clouds. In this study, laboratory and field-based cirrus crystal drag coefficient data, as well as analytical descriptions of cirrus crystal shapes, are used to derive more physically based expressions for the velocities of cirrus crystals than have been available in the past.Polycrystals-often bullet rosettes-are shown to be the dominant crystal types in synoptically generated cirrus, with columns present in varying but relatively large percentages, depending on the cloud. The two critical parameters needed to calculate terminal velocity are the drag coefficient and the ratio of mass to cross-sectional area normal to their fall direction. Using measurements and calculations, it is shown that drag coefficients from theory and laboratory studies are applicable to crystals of the types found in cirrus. The ratio of the mass to area, which is shown to be relatively independent of the number of bullets in the rosette, is derived from an analytic model that represents bullet rosettes containing one to eight bullets in 19 primary geometric configurations. The ratio is also derived for columns. Using this information, a general set of equations is developed to calculate the terminal velocities and masses in terms of the aspect ratio (width divided by length), ice density, and rosette maximum dimension. Simple expressions for terminal velocity and mass as a function of bullet rosette maximum dimension are developed by incorporating new information on bullet aspect ratios.The general terminal velocity and mass relations are then applied to a case from the First International Satellite Cloud Climatology Project (ISCCP) Research Experiment (FIRE) 2, when size spectra from a balloon-borne ice crystal

  7. Advanced PDV velocity extraction

    NASA Astrophysics Data System (ADS)

    Dolan, Daniel; Ao, Tommy; Furnish, Michael

    2015-06-01

    While PDV has become a standard diagnostic, reliable velocity extraction remains challenging. Measurements with multiple real/apparent velocities are intrinsically difficult to analyze, and overlapping frequency components invalidate standard extraction methods. This presentation describes an advanced analysis technique where overlapping frequency components are resolved in the complex Fourier spectrum. Practical matters--multiple region of interest selection, component intersection, and shock transitions--will also be discussed. Sandia National Laboratories is a multi-program laboratory operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85.

  8. Velocity pump reaction turbine

    DOEpatents

    House, P.A.

    An expanding hydraulic/two-phase velocity pump reaction turbine including a dual concentric rotor configuration with an inter-rotor annular flow channel in which the inner rotor is mechanically driven by the outer rotor. In another embodiment, the inner rotor is immobilized and provided with gas recovery ports on its outer surface by means of which gas in solution may be recovered. This velocity pump reaction turbine configuration is capable of potential energy conversion efficiencies of up to 70%, and is particularly suited for geothermal applications.

  9. Velocity pump reaction turbine

    DOEpatents

    House, Palmer A.

    1984-01-01

    An expanding hydraulic/two-phase velocity pump reaction turbine including a dual concentric rotor configuration with an inter-rotor annular flow channel in which the inner rotor is mechanically driven by the outer rotor. In another embodiment, the inner rotor is immobilized and provided with gas recovery ports on its outer surface by means of which gas in solution may be recovered. This velocity pump reaction turbine configuration is capable of potential energy conversion efficiencies of up to 70%, and is particularly suited for geothermal applications.

  10. Velocity pump reaction turbine

    DOEpatents

    House, Palmer A.

    1982-01-01

    An expanding hydraulic/two-phase velocity pump reaction turbine including a dual concentric rotor configuration with an inter-rotor annular flow channel in which the inner rotor is mechanically driven by the outer rotor. In another embodiment, the inner rotor is immobilized and provided with gas recovery ports on its outer surface by means of which gas in solution may be recovered. This velocity pump reaction turbine configuration is capable of potential energy conversion efficiencies of up to 70%, and is particularly suited for geothermal applications.

  11. MSE velocity survey

    NASA Astrophysics Data System (ADS)

    Schimd, C.; Courtois, H.; Koda, J.

    2015-12-01

    A huge velocity survey based on the Maunakea Spectroscopic Explorer facility (MSE) is proposed, aiming at investigating the structure and dynamics of the cosmic web over 3π steradians up to ˜1 Gpc and at unprecedented spatial resolution, its relationship with the galaxy formation process, and the bias between galaxies and dark matter during the last three billions years. The cross-correlation of velocity and density fields will further allow the probe any deviation from General Relativity by measuring the the linear-growth rate of cosmic structures at precision competitive with high-redshift spectroscopic redshift surveys.

  12. A new instrumentation for particle velocity and velocity related measurements under water

    NASA Astrophysics Data System (ADS)

    Zhu, Weijia

    This dissertation investigates the capability of a new instrument for small particle velocity measurement and velocity related signal analysis in an underwater environment. This research started from the laser beam quality test, which was performed in air. It was conducted mainly by means of an optical fiber sensor combined with a computer controlled stepping motor as well as two other methods, edge detection and needle-tip scattering. The stepping motor offers a constant velocity to the fiber sensor, so that the beam separation can be accurately measured by using the constant velocity value and the transit time determined by the cross correlation function of two digital signals. Meanwhile, information of the beam intensity profile, the parallelism of the two beams and the in-air beam widths can also be obtained in the test. By using the calibrated beam separation of the ribbon pair in the beam quality test, particle velocity measurements are carried out based on the relation between velocity, displacement and time in a 500-liter open water tank. The time delay for a particle crossing over the two ribbons in sequence is obtained by computing the cross correlation of the two signals. In fact, the time delay is actually a statistical mean value of many particles that cross over the ribbons in a short time. So is the measured velocity. The third part of this research is the practical study on pulse shape analysis based on the data sets of the velocity measurement. Several computer programs are developed to explore the pulse height distribution in a data set, to study the pulse degeneration, the relationship between the pulse width and the velocity, and the in-water beam width information. Some important reference materials are displayed in the appendices such as the fundamentals of the cross correlation and auto correlation, three main MATLAB programs developed for this research, the theoretical analysis of particle diffraction.

  13. Air resistance measurements on actual airplane parts

    NASA Technical Reports Server (NTRS)

    Weiselsberger, C

    1923-01-01

    For the calculation of the parasite resistance of an airplane, a knowledge of the resistance of the individual structural and accessory parts is necessary. The most reliable basis for this is given by tests with actual airplane parts at airspeeds which occur in practice. The data given here relate to the landing gear of a Siemanms-Schuckert DI airplane; the landing gear of a 'Luftfahrzeug-Gesellschaft' airplane (type Roland Dlla); landing gear of a 'Flugzeugbau Friedrichshafen' G airplane; a machine gun, and the exhaust manifold of a 269 HP engine.

  14. Explosive Percolation Transition is Actually Continuous

    NASA Astrophysics Data System (ADS)

    da Costa, R. A.; Dorogovtsev, S. N.; Goltsev, A. V.; Mendes, J. F. F.

    2010-12-01

    Recently a discontinuous percolation transition was reported in a new “explosive percolation” problem for irreversible systems [D. Achlioptas, R. M. D’Souza, and J. Spencer, Science 323, 1453 (2009)SCIEAS0036-807510.1126/science.1167782] in striking contrast to ordinary percolation. We consider a representative model which shows that the explosive percolation transition is actually a continuous, second order phase transition though with a uniquely small critical exponent of the percolation cluster size. We describe the unusual scaling properties of this transition and find its critical exponents and dimensions.

  15. Immigration policy, foreign agricultural labor, and exit intentions in the United States dairy industry.

    PubMed

    Susanto, D; Rosson, C P; Anderson, D P; Adcock, F J

    2010-04-01

    United States agriculture is dependent on foreign labor. Current US immigration policies have been alleged to disrupt agricultural labor availability, particularly that of hired foreign labor. A national survey of dairy farmers across herd sizes and regions of the United States was conducted and the results were used to estimate the extent to which hired foreign labor dependency will affect exit intentions in dairy farming. This study found that the expected probability of exit from dairy farming increased as the use of hired foreign labor intensified. But the expected probability of exit also decreased rapidly as herd sizes got larger. Given the immigration policy currently in place, farmers expecting labor shortages in the future are expected to experience greater tendency to exit the industry.

  16. Development of EXITE3, Imaging Detectors and a Long Duration Balloon Gondola

    NASA Technical Reports Server (NTRS)

    2003-01-01

    In this Report we summarize the work conducted for the EXITE program under grant NAG5-5103. This grant supported the ongoing EXITE program at Harvard for the development of imaging hard x-ray detectors and telescopes over the 3 year period 1997-2000 with a one year extension to 2001 to transition to the next SR&T grant in this program. Work was conducted in three major parts: analysis of the EXITE2 balloon flight data (from our May 1997 flight); development of pixellated imaging Cd-Zn-Te detector arrays and readout systems for the proposed EXITE3 detector and telescope; and development of systems for a Long Duration Balloon (LDB) gondola. Progress on all three major aspects of this research is summarized for each of the years of this grant.

  17. Interior of east side exit, view facing eastsoutheast U.S. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior of east side exit, view facing east-southeast - U.S. Naval Base, Pearl Harbor, Type "B" Casualty Dressing & Decontamination Station, Intersection of Eighth Street, Avenue E & Central Avenue, Pearl City, Honolulu County, HI

  18. Immigration policy, foreign agricultural labor, and exit intentions in the United States dairy industry.

    PubMed

    Susanto, D; Rosson, C P; Anderson, D P; Adcock, F J

    2010-04-01

    United States agriculture is dependent on foreign labor. Current US immigration policies have been alleged to disrupt agricultural labor availability, particularly that of hired foreign labor. A national survey of dairy farmers across herd sizes and regions of the United States was conducted and the results were used to estimate the extent to which hired foreign labor dependency will affect exit intentions in dairy farming. This study found that the expected probability of exit from dairy farming increased as the use of hired foreign labor intensified. But the expected probability of exit also decreased rapidly as herd sizes got larger. Given the immigration policy currently in place, farmers expecting labor shortages in the future are expected to experience greater tendency to exit the industry. PMID:20338458

  19. 29 CFR 1910.36 - Design and construction requirements for exit routes.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... exit route must be covered if snow or ice is likely to accumulate along the route, unless the employer can demonstrate that any snow or ice accumulation will be removed before it presents a slipping...

  20. Simulation study of the role of the ribosomal exit tunnel on protein folding

    NASA Astrophysics Data System (ADS)

    Chen, Changjun; Wang, Ercheng; Liu, Pengyu; Xiao, Yi

    2013-02-01

    To investigate the role of the ribosomal exit tunnel on protein folding, we simulate the initial-stage folding behavior of the protein villin headpiece subdomain HP35 (PDB id: 1yrf) with and without prefolding in the exit tunnel by using an all-atom model and find that prefolding in the exit tunnel could effectively help the protein form native secondary structures. Furthermore, our results show that, after releasing from the exit tunnel, the prefolded chains may have a tendency to form more native contacts than those only in free space and this reduces the conformational space of sampling. Our results may provide an alternative way to explain the fast folding mechanism of proteins in vivo.

  1. Siah regulation of Pard3A controls neuronal cell adhesion during germinal zone exit.

    PubMed

    Famulski, Jakub K; Trivedi, Niraj; Howell, Danielle; Yang, Yuan; Tong, Yiai; Gilbertson, Richard; Solecki, David J

    2010-12-24

    The brain's circuitry is established by directed migration and synaptogenesis of neurons during development. Although neurons mature and migrate in specific patterns, little is known about how neurons exit their germinal zone niche. We found that cerebellar granule neuron germinal zone exit is regulated by proteasomal degradation of Pard3A by the Seven in Absentia homolog (Siah) E3 ubiquitin ligase. Pard3A gain of function and Siah loss of function induce precocious radial migration. Time-lapse imaging using a probe to measure neuronal cell contact reveals that Pard3A promotes adhesive interactions needed for germinal zone exit by recruiting the epithelial tight junction adhesion molecule C to the neuronal cell surface. Our findings define a Siah-Pard3A signaling pathway that controls adhesion-dependent exit of neuronal progenitors or immature neurons from a germinal zone niche.

  2. Dynamic auditory localization: systematic replication of the auditory velocity function.

    PubMed

    Perrott, D R; Buck, V; Waugh, W; Strybel, T Z

    1979-10-01

    Two experiments explored the capability of normal-hearing adults to judge the apparent velocity of an unseen moving sound source. In exper. I, 9 naive and, 1 experienced S judged the velocity of a moving source emitting a .5-kc/s tone at 50 db SPL. S's head was in the center of a circle of 1.88-m radius swept by a small loudspeaker. In exper. II the sound was a low-pass-filtered (0.1-1 kc/s) noise at 50 db sound spectrum level. In both experiments perceived velocity was directly proportional to the actual velocity of the source. These results support out initial observations (Waugh et al, J. Aud. Res., 1979, 19, 103-1 10) that auditory velocity discrimination can be described as a power function with an exponent of 1.0. In exper. II the Ss also varied the sound source velocity by means of a variable resistor to produce a perceived velocity of 100 degrees/sec. Performance on the adaptive velocity production task was successfully predicted from the data of the absolute velocity judgment task. The Weber fraction was .052 for relatively fast-moving sound sources (100 degrees/sec). The ability to discriminate sound source velocity appears to be a well-defined feature of the dynamic binaural spatial system. PMID:262464

  3. Modeling Terminal Velocity

    ERIC Educational Resources Information Center

    Brand, Neal; Quintanilla, John A.

    2013-01-01

    Using a simultaneously falling softball as a stopwatch, the terminal velocity of a whiffle ball can be obtained to surprisingly high accuracy with only common household equipment. This classroom activity engages students in an apparently daunting task that nevertheless is tractable, using a simple model and mathematical techniques at their…

  4. Noise from Supersonic Coaxial Jets. Part 2; Normal Velocity Profile

    NASA Technical Reports Server (NTRS)

    Dahl, M. D.; Morris, P. J.

    1997-01-01

    Instability waves have been established as noise generators in supersonic jets. Recent analysis of these slowly diverging jets has shown that these instability waves radiate noise to the far field when the waves have components with phase velocities that are supersonic relative to the ambient speed of sound. This instability wave noise generation model has been applied to supersonic jets with a single shear layer and is now applied to supersonic coaxial jets with two initial shear layers. In this paper the case of coaxial jets with normal velocity profiles is considered, where the inner jet stream velocity is higher than the outer jet stream velocity. To provide mean flow profiles at all axial locations, a numerical scheme is used to calculate the mean flow properties. Calculations are made for the stability characteristics in the coaxial jet shear layers and the noise radiated from the instability waves for different operating conditions with the same total thrust, mass flow and exit area as a single reference jet. The effects of changes in the velocity ratio, the density ratio and the area ratio are each considered independently.

  5. Intraglottal geometry and velocity measurements in canine larynges

    PubMed Central

    Oren, Liran; Khosla, Sid; Gutmark, Ephraim

    2014-01-01

    Previous flow velocity measurements during phonation in canine larynges were done above the glottal exit. These studies found that vortical structures are present in the flow above the glottis at different phases of the glottal cycle. Some vortices were observed to leave the glottis during the closing phase and assumptions were proposed regarding their formation mechanism. In the current study, intraglottal velocity measurements are performed using PIV, and the intraglottal flow characteristics are determined. Results from five canine larynges show that at low subglottal pressure the glottis assumes a minimal divergence angle during closing and the flow separates at the glottal exit. Vortical structures are observed above the glottis but not inside. As the subglottal pressure is increased, the divergence angle between the folds during closing increases and the location of the flow separation moves upstream into the glottis. Entrainment flow enters the glottis to fill the void that is formed between the glottal jet and the fold. Vortical structures develop near the superior edge at medium and high subglottal pressures from the flow separation. The magnitude of their swirling strength changes as a function of the wall dynamics. PMID:24437778

  6. Response of polymer composites to high and low velocity impact

    NASA Technical Reports Server (NTRS)

    Hsieh, C. Y.; Mount, A.; Jang, B. Z.; Zee, R. H.

    1990-01-01

    The present investigation of fiber-reinforced polymer matrix composites' impact characteristics employed a drop tower for the low-velocity impact case and a novel, projectile instantaneous velocity-measuring sensor for high-velocity impact. Attention was given to the energy loss of projectiles in composites reinforced with polyethylene, kevlar, and graphite. Two distinct energy-loss mechanisms are noted, the first of which is due to the actual fracture process while the other is due to the generation of friction heat. The drop-tower impact-test results furnish the strain-rate dependence of the energy loss.

  7. IR signature study of aircraft engine for variation in nozzle exit area

    NASA Astrophysics Data System (ADS)

    Baranwal, Nidhi; Mahulikar, Shripad P.

    2016-01-01

    In general, jet engines operate with choked nozzle during take-off, climb and cruise, whereas unchoking occurs while landing and taxiing (when engine is not running at full power). Appropriate thrust in an aircraft in all stages of the flight, i.e., take-off, climb, cruise, descent and landing is achieved through variation in the nozzle exit area. This paper describes the effect on thrust and IR radiance of a turbojet engine due to variation in the exit area of a just choked converging nozzle (Me = 1). The variations in the nozzle exit area result in either choking or unchoking of a just choked converging nozzle. Results for the change in nozzle exit area are analyzed in terms of thrust, mass flow rate and specific fuel consumption. The solid angle subtended (Ω) by the exhaust system is estimated analytically, for the variation in nozzle exit area (Ane), as it affects the visibility of the hot engine parts from the rear aspect. For constant design point thrust, IR radiance is studied from the boresight (ϕ = 0°, directly from the rear side) for various percentage changes in nozzle exit area (%ΔAne), in the 1.9-2.9 μm and 3-5 μm bands.

  8. On the IMF BY dependence on polar cap patch exits at night

    NASA Astrophysics Data System (ADS)

    Moen, J.; Hosokawa, K.; Gulbrandsen, N.

    2012-04-01

    Polar cap patches are islands of enhanced F-region electron density within the polar cap. They form near the cusp inflow region at day, transit the polar cap when frozen into twin-cell convection, and finally exit the polar cap at night into the night time auroras. When exiting they change status from patches to blobs. Monitoring the presence of F-region plasma structures and their travel path is essential in order to develop reliable space weather forecasts for the high latitude ionosphere in future. This paper presents a comprehensive study of a sequence of polar cap patches that exit the polar cap. Superimposing satellite images of the auroral oval and all-sky camera observations of airglow patches onto SuperDARN convection maps for an extended time period around magnetic midnight, provides an unparalleled opportunity to examine how plasma exits the polar cap. Under conditions of IMF BY predominantly positive (+5nT) we find that the patches exit both into the oval on the dusk cell pre midnight and on the dusk cell post midnight. This event study concurs with a statistical result also presented. The statistics show that the MLT distribution of patch exits, which is a ~10 hours broad bell shaped function cantered on ~23:30 MLT, is just marginally sensitive to the IMF BY polarity. This makes us conclude that the patches do not memorize on which cell they entered the polar cap.

  9. Performance Characteristics of Flush and Shielded Auxiliary Exits at Mach Numbers of 1.5 to 2.0

    NASA Technical Reports Server (NTRS)

    Abdalla, Kaleel L.

    1959-01-01

    The performance characteristics of several flush and shielded auxiliary exits were investigated at Mach numbers of 1.5 to 2.0, and jet pressure ratios from jet off to 10. The results indicate that the shielded configurations produced better overall performance than the corresponding flush exits over the Mach-number and pressure-ratio ranges investigated. Furthermore, the full-length shielded exit was highest in performance of all the configurations. The flat-exit nozzle block provided considerably improved performance compared with the curved-exit nozzle block.

  10. Simulating photospheric Doppler velocity fields

    NASA Technical Reports Server (NTRS)

    Hathaway, David H.

    1988-01-01

    A method is described for constructing artificial data that realistically simulate photospheric velocity fields. The velocity fields include rotation, differential rotation, meridional circulation, giant cell convection, supergranulation, convective limb shift, p-mode oscillations, and observer motion. Data constructed by this method can be used for testing algorithms designed to extract and analyze these velocity fields in real Doppler velocity data.

  11. Evolution of planetesimal velocities

    NASA Technical Reports Server (NTRS)

    Stewart, Glen R.; Wetherill, George W.

    1987-01-01

    A self-consistent set of equations for the velocity evolution of a general planetesimal population is presented. The equations are given in a form convenient for calculations of the early stages of planetary accumulation when it is necessary to model the planetesimal swarm by methods of gas dynamics, rather than follow the orbital evolution of individual bodies. Steady state velocities of a simple planetesimal population consisting of two different sizes of bodies are calculated. Dynamical friction is found to be an important mechanism for transferring kinetic energy from the larger planetesimals to the smaller ones. When the small planetesimals are relatively abundant, gas drag and inelastic collisions among the smaller bodies are of comparable importance for dissipating energy from the population.

  12. The actual status of Astronomy in Moldova

    NASA Astrophysics Data System (ADS)

    Gaina, A.

    The astronomical research in the Republic of Moldova after Nicolae Donitch (Donici)(1874-1956(?)) were renewed in 1957, when a satellites observations station was open in Chisinau. Fotometric observations and rotations of first Soviet artificial satellites were investigated under a program SPIN put in action by the Academy of Sciences of former Socialist Countries. The works were conducted by Assoc. prof. Dr. V. Grigorevskij, which conducted also research in variable stars. Later, at the beginning of 60-th, an astronomical Observatory at the Chisinau State University named after Lenin (actually: the State University of Moldova), placed in Lozovo-Ciuciuleni villages was open, which were coordinated by Odessa State University (Prof. V.P. Tsesevich) and the Astrosovet of the USSR. Two main groups worked in this area: first conducted by V. Grigorevskij (till 1971) and second conducted by L.I. Shakun (till 1988), both graduated from Odessa State University. Besides this research areas another astronomical observations were made: Comets observations, astroclimate and atmospheric optics in collaboration with the Institute of the Atmospheric optics of the Siberian branch of the USSR (V. Chernobai, I. Nacu, C. Usov and A.F. Poiata). Comets observations were also made since 1988 by D. I. Gorodetskij which came to Chisinau from Alma-Ata and collaborated with Ukrainean astronomers conducted by K.I. Churyumov. Another part of space research was made at the State University of Tiraspol since the beggining of 70-th by a group of teaching staff of the Tiraspol State Pedagogical University: M.D. Polanuer, V.S. Sholokhov. No a collaboration between Moldovan astronomers and Transdniestrian ones actually exist due to War in Transdniestria in 1992. An important area of research concerned the Radiophysics of the Ionosphere, which was conducted in Beltsy at the Beltsy State Pedagogical Institute by a group of teaching staff of the University since the beginning of 70-th: N. D. Filip, E

  13. MODIS Solar Diffuser: Modelled and Actual Performance

    NASA Technical Reports Server (NTRS)

    Waluschka, Eugene; Xiong, Xiao-Xiong; Esposito, Joe; Wang, Xin-Dong; Krebs, Carolyn (Technical Monitor)

    2001-01-01

    The Moderate Resolution Imaging Spectroradiometer (MODIS) instrument's solar diffuser is used in its radiometric calibration for the reflective solar bands (VIS, NTR, and SWIR) ranging from 0.41 to 2.1 micron. The sun illuminates the solar diffuser either directly or through a attenuation screen. The attenuation screen consists of a regular array of pin holes. The attenuated illumination pattern on the solar diffuser is not uniform, but consists of a multitude of pin-hole images of the sun. This non-uniform illumination produces small, but noticeable radiometric effects. A description of the computer model used to simulate the effects of the attenuation screen is given and the predictions of the model are compared with actual, on-orbit, calibration measurements.

  14. 7 CFR 1437.101 - Actual production history.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Actual production history. 1437.101 Section 1437.101... Determining Yield Coverage Using Actual Production History § 1437.101 Actual production history. Actual production history (APH) is the unit's record of crop yield by crop year for the APH base period. The...

  15. 7 CFR 1437.101 - Actual production history.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Actual production history. 1437.101 Section 1437.101... Determining Yield Coverage Using Actual Production History § 1437.101 Actual production history. Actual production history (APH) is the unit's record of crop yield by crop year for the APH base period. The...

  16. 7 CFR 1437.101 - Actual production history.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Actual production history. 1437.101 Section 1437.101... Determining Yield Coverage Using Actual Production History § 1437.101 Actual production history. Actual production history (APH) is the unit's record of crop yield by crop year for the APH base period. The...

  17. 7 CFR 1437.101 - Actual production history.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Actual production history. 1437.101 Section 1437.101... Determining Yield Coverage Using Actual Production History § 1437.101 Actual production history. Actual production history (APH) is the unit's record of crop yield by crop year for the APH base period. The...

  18. 7 CFR 1437.101 - Actual production history.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Actual production history. 1437.101 Section 1437.101... Determining Yield Coverage Using Actual Production History § 1437.101 Actual production history. Actual production history (APH) is the unit's record of crop yield by crop year for the APH base period. The...

  19. Evolution of planetesimal velocities

    NASA Astrophysics Data System (ADS)

    Stewart, G. R.; Wetherill, G. W.

    1988-06-01

    A self-consistent set of equations for the velocity evolution of a general planetesimal population is presented. Dynamical friction is found to be an important mechanism for transferring kinetic energy from the larger planetesimals to the smaller ones, providing an energy source for the small planetesimals that is comparable to that provided by the viscous stirring process. When small planetesimals are relatively abundant, gas drag and inelastic collisions among the smaller bodies are of comparable importance for dissipating energy from the population.

  20. On the Exit Boundary Condition for One-Dimensional Calculations of Pulsed Detonation Engine Performance

    NASA Technical Reports Server (NTRS)

    Wilson, Jack; Paxson, Daniel E.

    2002-01-01

    In one-dimensional calculations of pulsed detonation engine (PDE) performance, the exit boundary condition is frequently taken to be a constant static pressure. In reality, for an isolated detonation tube, after the detonation wave arrives at the exit plane, there will be a region of high pressure, which will gradually return to ambient pressure as an almost spherical shock wave expands away from the exit, and weakens. Initially, the flow is supersonic, unaffected by external pressure, but later becomes subsonic. Previous authors have accounted for this situation either by assuming the subsonic pressure decay to be a relaxation phenomenon, or by running a two-dimensional calculation first, including a domain external to the detonation tube, and using the resulting exit pressure temporal distribution as the boundary condition for one-dimensional calculations. These calculations show that the increased pressure does affect the PDE performance. In the present work, a simple model of the exit process is used to estimate the pressure decay time. The planar shock wave emerging from the tube is assumed to transform into a spherical shock wave. The initial strength of the spherical shock wave is determined from comparison with experimental results. Its subsequent propagation, and resulting pressure at the tube exit, is given by a numerical blast wave calculation. The model agrees reasonably well with other, limited, results. Finally, the model was used as the exit boundary condition for a one-dimensional calculation of PDE performance to obtain the thrust wall pressure for a hydrogen-air detonation in tubes of length to diameter ratio (L/D) of 4, and 10, as well as for the original, constant pressure boundary condition. The modified boundary condition had no performance impact for values of L/D > 10, and moderate impact for L/D = 4.

  1. Global Phosphoproteomic Mapping of Early Mitotic Exit in Human Cells Identifies Novel Substrate Dephosphorylation Motifs.

    PubMed

    McCloy, Rachael A; Parker, Benjamin L; Rogers, Samuel; Chaudhuri, Rima; Gayevskiy, Velimir; Hoffman, Nolan J; Ali, Naveid; Watkins, D Neil; Daly, Roger J; James, David E; Lorca, Thierry; Castro, Anna; Burgess, Andrew

    2015-08-01

    Entry into mitosis is driven by the coordinated phosphorylation of thousands of proteins. For the cell to complete mitosis and divide into two identical daughter cells it must regulate dephosphorylation of these proteins in a highly ordered, temporal manner. There is currently a lack of a complete understanding of the phosphorylation changes that occur during the initial stages of mitotic exit in human cells. Therefore, we performed a large unbiased, global analysis to map the very first dephosphorylation events that occur as cells exit mitosis. We identified and quantified the modification of >16,000 phosphosites on >3300 unique proteins during early mitotic exit, providing up to eightfold greater resolution than previous studies. The data have been deposited to the ProteomeXchange with identifier PXD001559. Only a small fraction (∼ 10%) of phosphorylation sites were dephosphorylated during early mitotic exit and these occurred on proteins involved in critical early exit events, including organization of the mitotic spindle, the spindle assembly checkpoint, and reformation of the nuclear envelope. Surprisingly this enrichment was observed across all kinase consensus motifs, indicating that it is independent of the upstream phosphorylating kinase. Therefore, dephosphorylation of these sites is likely determined by the specificity of phosphatase/s rather than the activity of kinase/s. Dephosphorylation was significantly affected by the amino acids at and surrounding the phosphorylation site, with several unique evolutionarily conserved amino acids correlating strongly with phosphorylation status. These data provide a potential mechanism for the specificity of phosphatases, and how they co-ordinate the ordered events of mitotic exit. In summary, our results provide a global overview of the phosphorylation changes that occur during the very first stages of mitotic exit, providing novel mechanistic insight into how phosphatase/s specifically regulate this critical

  2. Identification of the effects of the nozzle-exit boundary-layer thickness and its corresponding Reynolds number in initially highly disturbed subsonic jets

    NASA Astrophysics Data System (ADS)

    Bogey, Christophe; Marsden, Olivier

    2013-05-01

    The influence of the nozzle-exit boundary-layer thickness in isothermal round jets at a Mach number of 0.9 and at diameter Reynolds numbers ReD ≃ 5 × 104 is investigated using large-eddy simulations. The originality of this work is that, contrary to previous studies on the topic, the jets are initially highly disturbed, and that the effects of the boundary-layer thickness are explored jointly on the exit turbulence, the shear-layer and jet flow characteristics, and the acoustic field. The jets originate from a pipe of radius r0, and exhibit, at the exit, peak disturbance levels of 9% of the jet velocity, and mean velocity profiles similar to laminar boundary-layer profiles of thickness δ0 = 0.09r0, 0.15r0, 0.25r0, or 0.42r0, yielding 99% velocity thicknesses between 0.07r0 and 0.34r0 and momentum thicknesses δθ(0) between 0.012r0 and 0.05r0. Two sets of computations are reported to distinguish, for the first time to the best of our knowledge, between the effects of the ratio δ0/r0 and of the Reynolds number Reθ based on δθ(0). First, four jets with a fixed diameter, hence at a constant Reynolds number ReD = 5 × 104 giving Reθ = 304, 486, 782, and 1288 depending on δ0, are considered. In this case, due to the increase in Reθ, thickening the initial shear layers mainly results in a weaker mixing-layer development with lower spreading rates and turbulence intensities, and reduced sound levels at all emission angles. Second, four jets at Reynolds numbers ReD between 1.8 × 104 and 8.3 × 104, varying so as to obtain Reθ ≃ 480 in all simulations, are examined. Here, increasing δ0/r0 has a limited impact on the mixing-layer key features, but clearly leads to a shorter potential core, a more rapid velocity decay, and higher fluctuations on the jet axis, and stronger noise in the downstream direction. Similar trends can be expected for high-Reynolds-number jets in which viscosity plays a negligible role.

  3. Do Disk Galaxies Have Different Central Velocity Dispersions At A Given Rotation Velocity?

    NASA Astrophysics Data System (ADS)

    Danilovich, Taissa; Jones, H.; Mould, J.; Taylor, E.; Tonini, C.; Webster, R.

    2011-05-01

    Hubble's classification of spiral galaxies was one dimensional. Actually it was 1.5 dimensional, as he distinguished barred spirals. Van den Bergh's was two dimensional: spirals had luminosity classes too. Other schemes are summarized at http://www.daviddarling.info/encyclopedia/G/galaxyclassification.html A more quantitative approach is to classify spiral galaxies by rotation velocity. Their central velocity dispersion (bulge) tends to be roughly one half of their rotation velocity (disk). There is a trend from σ/W = 0.8 to σ/W = 0.2 as one goes from W = 100 to 500 km/s, where W is twice the rotation velocity. But some fraction of spirals have a velocity dispersion up to a factor of two larger than that. In hierarchical galaxy formation models, the relative contributions of σ and W depend on the mass accretion history of the galaxy, which determines the mass distribution of the dynamical components such as disk, bulge and dark matter halo. The wide variety of histories that originate in the hierarchical mass assembly produce at any value of W a wide range of σ/W, that reaches high values in more bulge- dominated systems. In a sense the two classifiers were both right: spirals are mostly one dimensional, but σ/W (bulge to disk ratio) is often larger than average. Is this a signature of merger history?

  4. Turbulence characteristics of a plane diffuser flow with inlet velocity distortion

    NASA Astrophysics Data System (ADS)

    Aswatha Narayana, P. A.; Chandrasekhara, N. V.; Chithambaran, V. K.

    1984-04-01

    An experimental study of turbulent characteristics of incompressible flow in a two-dimensional diffuser with inlet velocity distortion is reported. Turbulence level in the boundary layer increases marginally towards the exit of the diffuser and decreases rapidly in the wake region. The region of maximum velocity fluctuation and the maximum Reynolds shear stress shifts away from the wall in the streamwise direction. The energy spectra of the turbulent kinetic energy in the wake region shows a characteristic behaviour indicating possible vortex shedding from the trailing edge of the airfoil.

  5. Caustic-Side Solvent Extraction: Prediction of Cesium Extraction for Actual Wastes and Actual Waste Simulants

    SciTech Connect

    Delmau, L.H.; Haverlock, T.J.; Sloop, F.V., Jr.; Moyer, B.A.

    2003-02-01

    This report presents the work that followed the CSSX model development completed in FY2002. The developed cesium and potassium extraction model was based on extraction data obtained from simple aqueous media. It was tested to ensure the validity of the prediction for the cesium extraction from actual waste. Compositions of the actual tank waste were obtained from the Savannah River Site personnel and were used to prepare defined simulants and to predict cesium distribution ratios using the model. It was therefore possible to compare the cesium distribution ratios obtained from the actual waste, the simulant, and the predicted values. It was determined that the predicted values agree with the measured values for the simulants. Predicted values also agreed, with three exceptions, with measured values for the tank wastes. Discrepancies were attributed in part to the uncertainty in the cation/anion balance in the actual waste composition, but likely more so to the uncertainty in the potassium concentration in the waste, given the demonstrated large competing effect of this metal on cesium extraction. It was demonstrated that the upper limit for the potassium concentration in the feed ought to not exceed 0.05 M in order to maintain suitable cesium distribution ratios.

  6. Acoustic velocity meter systems

    USGS Publications Warehouse

    Laenen, Antonius

    1985-01-01

    Acoustic velocity meter (AVM) systems operate on the principles that the point-to-point upstream traveltime of an acoustic pulse is longer than the downstream traveltime and that this difference in traveltime can be accurately measured by electronic devices. An AVM system is capable of recording water velocity (and discharge) under a wide range of conditions, but some constraints apply: 1. Accuracy is reduced and performance is degraded if the acoustic path is not a continuous straight line. The path can be bent by reflection if it is too close to a stream boundary or by refraction if it passes through density gradients resulting from variations in either water temperature or salinity. For paths of less than 100 m, a temperature gradient of 0.1' per meter causes signal bending less than 0.6 meter at midchannel, and satisfactory velocity results can be obtained. Reflection from stream boundaries can cause signal cancellation if boundaries are too close to signal path. 2. Signal strength is attenuated by particles or bubbles that absorb, spread, or scatter sound. The concentration of particles or bubbles that can be tolerated is a function of the path length and frequency of the acoustic signal. 3. Changes in streamline orientation can affect system accuracy if the variability is random. 4. Errors relating to signal resolution are much larger for a single threshold detection scheme than for multiple threshold schemes. This report provides methods for computing the effect of various conditions on the accuracy of a record obtained from an AVM. The equipment must be adapted to the site. Field reconnaissance and preinstallation analysis to detect possible problems are critical for proper installation and operation of an AVM system.

  7. Thermal regime, predation danger and the early marine exit of sockeye salmon Oncorhynchus nerka.

    PubMed

    Katinic, P J; Patterson, D A; Ydenberg, R C

    2015-01-01

    Marine exit timing of sockeye salmon Oncorhynchus nerka populations on the Haida Gwaii Archipelago, British Columbia, Canada, is described, with specific focus on Copper Creek. Marine exit in Copper Creek occurs > 130 days prior to spawning, one of the longest adult freshwater residence periods recorded for any O. nerka population. Copper Creek presents an easy upstream migration, with mild water temperatures (7 to 14°  C), short distance (13·1 km) and low elevation gain (41 m) to the lake where fish hold prior to spawning. An energetic model estimates that <1% of the initial energy reserve is required for upstream migration, compared with 62% for lake holding and 38% for reproductive development. Historical records suggest that it is unlikely that water temperature in any of the O.nerka streams in Haida Gwaii has ever exceeded the presumed temperature threshold (19° C) for early marine exit. Although it is not impossible that the thermal tolerance of Copper Creek O.nerka is very low, the data presented here appear inconsistent with thermal avoidance as an explanation for the early marine exit timing in Copper Creek and in three other populations on the archipelago with early marine exit. PMID:25494933

  8. Runway Exit Designs for Capacity Improvement Demonstrations. Phase 1: Algorithm Development

    NASA Technical Reports Server (NTRS)

    Trani, A. A.; Hobeika, A. G.; Sherali, H.; Kim, B. J.; Sadam, C. K.

    1990-01-01

    A description and results are presented of a study to locate and design rapid runway exits under realistic airport conditions. The study developed a PC-based computer simulation-optimization program called REDIM (runway exit design interactive model) to help future airport designers and planners to locate optimal exits under various airport conditions. The model addresses three sets of problems typically arising during runway exit design evaluations. These are the evaluations of existing runway configurations, addition of new rapid runway turnoffs, and the design of new runway facilities. The model is highly interactive and allows a quick estimation of the expected value of runway occupancy time. Aircraft populations and airport environmental conditions are among the multiple inputs to the model to execute a viable runway location and geometric design solution. The results presented suggest that possible reductions on runway occupancy time (ROT) can be achieved with the use of optimally tailored rapid runway designs for a given aircraft population. Reductions of up to 9 to 6 seconds are possible with the implementation of 30 m/sec variable geometry exits.

  9. Exit from sliding in piecewise-smooth flows: Deterministic vs. determinacy-breaking.

    PubMed

    Jeffrey, Mike R

    2016-03-01

    The collapse of flows onto hypersurfaces where their vector fields are discontinuous creates highly robust states called sliding modes. The way flows exit from such sliding modes can lead to complex and interesting behaviour about which little is currently known. Here, we examine the basic mechanisms by which a flow exits from sliding, either along a switching surface or along the intersection of two switching surfaces, with a view to understanding sliding and exit when many switches are involved. On a single switching surface, exit occurs via tangency of the flow to the switching surface. Along an intersection of switches, exit can occur at a tangency with a lower codimension sliding flow, or by a spiralling of the flow that exhibits geometric divergence (infinite steps in finite time). Determinacy-breaking can occur where a singularity creates a set-valued flow in an otherwise deterministic system, and we resolve such dynamics as far as possible by blowing up the switching surface into a switching layer. We show preliminary simulations exploring the role of determinacy-breaking events as organizing centres of local and global dynamics. PMID:27036186

  10. Bed-exit alarms. A component (but only a component) of fall prevention.

    PubMed

    2004-05-01

    Patient falls are a common cause of morbidity, nonfatal injuries, and trauma-related hospitalizations in the United States. Sometimes, they're even fatal. Falls typically occur either while the patient is getting into or out of bed or shortly after the patient has exited the bed. One means of helping to reduce the number of patient falls is the bed-exit alarm. Such alarms can be either built-in devices incorporated into the beds themselves or stand-alone units consisting of a portable control unit and a pressure- or position-sensitive sensor. They can serve as an "early warning system" alerting nursing staff when patients attempt to leave their beds unassisted. However, bed-exit alarms do not themselves prevent falls--a fact that is not always clearly understood. To be effective, they need to be implemented with care and with a clear understanding of their limitations. In this article, we describe the types of stand-alone bed-exit alarms currently available on the market and provide guidance to facilities on how to implement them effectively. We also review the elements of an effective fall-prevention program and recount one hospital's success in reducing patient falls. We are in the process of conducting a comparative evaluation of a number of bed-exit alarms, which will be published in an upcoming issue of Health Devices.

  11. Histopathological detection of entry and exit holes in human skin wounds caused by firearms.

    PubMed

    Baptista, Marcus Vinícius; d'Ávila, Solange C G P; d'Ávila, Antônio Miguel M P

    2014-07-01

    The judiciary needs forensic medicine to determine the difference between an entry hole and an exit hole in human skin caused by firearms for civilian use. This important information would be most useful if a practical and accurate method could be done with low-cost and minimal technological resources. Both macroscopic and microscopic analyses were performed on skin lesions caused by firearm projectiles, to establish histological features of 14 entry holes and 14 exit holes. Microscopically, in the abrasion area macroscopically observed, there were signs of burns (sub-epidermal cracks and keratinocyte necrosis) in the entrance holes in all cases. These signs were not found in three exit holes which showed an abrasion collar, nor in other exit holes. Some other microscopic features not found in every case were limited either to entry holes, such as cotton fibres, grease deposits, or tattooing in the dermis, or to exit holes, such as adipose tissue, bone or muscle tissue in the dermis. Coagulative necrosis of keratinocytes and sub-epidermal cracks are characteristic of entry holes. Despite the small sample size, it can be safely inferred that this is an important microscopic finding, among others less consistently found, to define an entry hole in questionable cases.

  12. Dark Matter Velocity Spectroscopy.

    PubMed

    Speckhard, Eric G; Ng, Kenny C Y; Beacom, John F; Laha, Ranjan

    2016-01-22

    Dark matter decays or annihilations that produce linelike spectra may be smoking-gun signals. However, even such distinctive signatures can be mimicked by astrophysical or instrumental causes. We show that velocity spectroscopy-the measurement of energy shifts induced by relative motion of source and observer-can separate these three causes with minimal theoretical uncertainties. The principal obstacle has been energy resolution, but upcoming experiments will have the precision needed. As an example, we show that the imminent Astro-H mission can use Milky Way observations to separate possible causes of the 3.5-keV line. We discuss other applications. PMID:26849582

  13. Dark Matter Velocity Spectroscopy.

    PubMed

    Speckhard, Eric G; Ng, Kenny C Y; Beacom, John F; Laha, Ranjan

    2016-01-22

    Dark matter decays or annihilations that produce linelike spectra may be smoking-gun signals. However, even such distinctive signatures can be mimicked by astrophysical or instrumental causes. We show that velocity spectroscopy-the measurement of energy shifts induced by relative motion of source and observer-can separate these three causes with minimal theoretical uncertainties. The principal obstacle has been energy resolution, but upcoming experiments will have the precision needed. As an example, we show that the imminent Astro-H mission can use Milky Way observations to separate possible causes of the 3.5-keV line. We discuss other applications.

  14. Halo velocity bias

    NASA Astrophysics Data System (ADS)

    Biagetti, Matteo; Desjacques, Vincent; Kehagias, Alex; Riotto, Antonio

    2014-11-01

    It has been recently shown that any halo velocity bias present in the initial conditions does not decay to unity, in agreement with predictions from peak theory. However, this is at odds with the standard formalism based on the coupled-fluids approximation for the coevolution of dark matter and halos. Starting from conservation laws in phase space, we discuss why the fluid momentum conservation equation for the biased tracers needs to be modified in accordance with the change advocated in Baldauf et al. Our findings indicate that a correct description of the halo properties should properly take into account peak constraints when starting from the Vlasov-Boltzmann equation.

  15. High velocity acoustics

    NASA Astrophysics Data System (ADS)

    Legendre, R.

    1992-09-01

    Different types of aerodynamically generated noise of practical interest are examined using a novel, physically based, approach. A simple source model for turbulence noise is proposed. The prediction for turbulent mixing layer noise, produced by this model based on a simple monopole-type source mechanism, is that the radiated sound power varies as the eighth power of the relative velocity. The model is too simple to allow calculations to be carried further to the extent of determining the radiated sound power level, so that an empirical factor must still be considered, as in the case of Lighthill's formula.

  16. Estimation of aerosol columnar size distribution and optical thickness from the angular distribution of radiance exiting the atmosphere: simulations.

    PubMed

    Wang, M; Gordon, H R

    1995-10-20

    We report the results of simulations in which an algorithm developed for estimation of aerosol optical properties from the angular distribution of radiance exiting the top of the atmosphere over the oceans [Appl. Opt. 33, 4042 (1994)] is combined with a technique for carrying out radiative transfer computations by synthesis of the radiance produced by individual components of the aerosol-size distribution [Appl. Opt. 33, 7088 (1994)], to estimate the aerosol-size distribution by retrieval of the total aerosol optical thickness and the mixing ratios for a set of candidate component aerosol-size distributions. The simulations suggest that in situations in which the true size-refractive-index distribution can actually be synthesized from a combination of the candidate components, excellent retrievals of the aerosol optical thickness and the component mixing ratios are possible. An exception is the presence of strongly absorbing aerosols. The angular distribution of radiance in a single spectral band does not appear to contain sufficient information to separate weakly from strongly absorbing aerosols. However, when two spectral bands are used in the algorithm, retrievals in the case of strongly absorbing aerosols are improved. When pseudodata were simulated with an aerosol-size distribution that differed in functional form from the candidate components, excellent retrievals were still obtained as long as the refractive indices of the actual aerosol model and the candidate components were similar. This underscores the importance of component candidates having realistic indices of refraction in the various size ranges for application of the method. The examples presented all focus on the multiangle imaging spectroradiometer; however, the results should be as valid for data obtained by the use of high-altitude airborne sensors. PMID:21060560

  17. Diversity Exiting the Academy: Influential Factors for the Career Choice of Well-Represented and Underrepresented Minority Scientists.

    PubMed

    Layton, Rebekah L; Brandt, Patrick D; Freeman, Ashalla M; Harrell, Jessica R; Hall, Joshua D; Sinche, Melanie

    2016-01-01

    A national sample of PhD-trained scientists completed training, accepted subsequent employment in academic and nonacademic positions, and were queried about their previous graduate training and current employment. Respondents indicated factors contributing to their employment decision (e.g., working conditions, salary, job security). The data indicate the relative importance of deciding factors influencing career choice, controlling for gender, initial interest in faculty careers, and number of postgraduate publications. Among both well-represented (WR; n = 3444) and underrepresented minority (URM; n = 225) respondents, faculty career choice was positively associated with desire for autonomy and partner opportunity and negatively associated with desire for leadership opportunity. Differences between groups in reasons endorsed included: variety, prestige, salary, family influence, and faculty advisor influence. Furthermore, endorsement of faculty advisor or other mentor influence and family or peer influence were surprisingly rare across groups, suggesting that formal and informal support networks could provide a missed opportunity to provide support for trainees who want to stay in faculty career paths. Reasons requiring alteration of misperceptions (e.g., limited leadership opportunity for faculty) must be distinguished from reasons requiring removal of actual barriers. Further investigation into factors that affect PhDs' career decisions can help elucidate why URM candidates are disproportionately exiting the academy. PMID:27587854

  18. Preliminary Analysis of the Effect of Flow Separation Due to Rocket Jet Pluming on Aircraft Dynamic Stability During Atmospheric Exit

    NASA Technical Reports Server (NTRS)

    Dryer, Murray; North, Warren J.

    1959-01-01

    A theoretical investigation was conducted to determine the effects of body boundary-layer separation resulting from a highly underexpanded jet on the dynamic stability of a typical rocket aircraft during an atmospheric exit trajectory. The particular flight condition studied on a digital computer for five degrees of freedom was at Mach 6.0 and 150,000 feet. In view of the unknown character of the separated flow field, two estimates of the pressures in the separated region were made to calculate the unbalanced forces and moments. These estimates, based on limited fundamental zero-angle-of-attack studies and observations, are believed to cover what may be the actual case. In addition to a fixed control case, two simulated pilot control inputs were studied: rate-limited and instantaneous responses. The resulting-motions with and without boundary-layer separation were compared for various initial conditions. The lower of the assumed misalinement forces and moments led to a situation whereby a slowly damped motion could be satisfactorily controlled with rate-limited control input. The higher assumption led to larger amplitude, divergent motions when the same control rates were used. These motions were damped only when the instantaneous control responses were assumed.

  19. Diversity Exiting the Academy: Influential Factors for the Career Choice of Well-Represented and Underrepresented Minority Scientists

    PubMed Central

    Layton, Rebekah L.; Brandt, Patrick D.; Freeman, Ashalla M.; Harrell, Jessica R.; Hall, Joshua D.; Sinche, Melanie

    2016-01-01

    A national sample of PhD-trained scientists completed training, accepted subsequent employment in academic and nonacademic positions, and were queried about their previous graduate training and current employment. Respondents indicated factors contributing to their employment decision (e.g., working conditions, salary, job security). The data indicate the relative importance of deciding factors influencing career choice, controlling for gender, initial interest in faculty careers, and number of postgraduate publications. Among both well-represented (WR; n = 3444) and underrepresented minority (URM; n = 225) respondents, faculty career choice was positively associated with desire for autonomy and partner opportunity and negatively associated with desire for leadership opportunity. Differences between groups in reasons endorsed included: variety, prestige, salary, family influence, and faculty advisor influence. Furthermore, endorsement of faculty advisor or other mentor influence and family or peer influence were surprisingly rare across groups, suggesting that formal and informal support networks could provide a missed opportunity to provide support for trainees who want to stay in faculty career paths. Reasons requiring alteration of misperceptions (e.g., limited leadership opportunity for faculty) must be distinguished from reasons requiring removal of actual barriers. Further investigation into factors that affect PhDs’ career decisions can help elucidate why URM candidates are disproportionately exiting the academy. PMID:27587854

  20. Diversity Exiting the Academy: Influential Factors for the Career Choice of Well-Represented and Underrepresented Minority Scientists.

    PubMed

    Layton, Rebekah L; Brandt, Patrick D; Freeman, Ashalla M; Harrell, Jessica R; Hall, Joshua D; Sinche, Melanie

    2016-01-01

    A national sample of PhD-trained scientists completed training, accepted subsequent employment in academic and nonacademic positions, and were queried about their previous graduate training and current employment. Respondents indicated factors contributing to their employment decision (e.g., working conditions, salary, job security). The data indicate the relative importance of deciding factors influencing career choice, controlling for gender, initial interest in faculty careers, and number of postgraduate publications. Among both well-represented (WR; n = 3444) and underrepresented minority (URM; n = 225) respondents, faculty career choice was positively associated with desire for autonomy and partner opportunity and negatively associated with desire for leadership opportunity. Differences between groups in reasons endorsed included: variety, prestige, salary, family influence, and faculty advisor influence. Furthermore, endorsement of faculty advisor or other mentor influence and family or peer influence were surprisingly rare across groups, suggesting that formal and informal support networks could provide a missed opportunity to provide support for trainees who want to stay in faculty career paths. Reasons requiring alteration of misperceptions (e.g., limited leadership opportunity for faculty) must be distinguished from reasons requiring removal of actual barriers. Further investigation into factors that affect PhDs' career decisions can help elucidate why URM candidates are disproportionately exiting the academy.

  1. CC chemokine receptor 7 required for T lymphocyte exit from peripheral tissues

    PubMed Central

    Debes, Gudrun F.; Arnold, Carrie N.; Young, Alan J.; Krautwald, Stefan; Lipp, Martin; Hay, John B.; Butcher, Eugene C.

    2006-01-01

    Lymphocytes travel throughout the body to carry out immune surveillance and participate in inflammatory reactions. Their path takes them from blood through tissues into lymph and back to blood. Molecules that control lymphocyte recruitment into extralymphoid tissues are well characterized, but exit is assumed to be random. Here, we showed that lymphocyte emigration from the skin was regulated and pertussis toxin-sensitive. CD4+ lymphocytes emigrated more efficiently than CD8+ or B lymphocytes. T lymphocytes in the afferent lymph expressed functional CCR7, and CCR7 was required for T lymphocyte exit from the skin. The regulated expression of CCR7 by tissue T lymphocytes may control their exit, acting with recruitment mechanisms to regulate lymphocyte transit and accumulation during immune surveillance and inflammation. PMID:16116468

  2. Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues.

    PubMed

    Debes, Gudrun F; Arnold, Carrie N; Young, Alan J; Krautwald, Stefan; Lipp, Martin; Hay, John B; Butcher, Eugene C

    2005-09-01

    Lymphocytes travel throughout the body to carry out immune surveillance and participate in inflammatory reactions. Their path takes them from blood through tissues into lymph and back to blood. Molecules that control lymphocyte recruitment into extralymphoid tissues are well characterized, but exit is assumed to be random. Here, we showed that lymphocyte emigration from the skin was regulated and was sensitive to pertussis toxin. CD4(+) lymphocytes emigrated more efficiently than CD8(+) or B lymphocytes. T lymphocytes in the afferent lymph expressed functional chemokine receptor CCR7, and CCR7 was required for T lymphocyte exit from the skin. The regulated expression of CCR7 by tissue T lymphocytes may control their exit, acting with recruitment mechanisms to regulate lymphocyte transit and accumulation during immune surveillance and inflammation. PMID:16116468

  3. Impact of a standardized test package on exit examination scores and NCLEX-RN outcomes.

    PubMed

    Homard, Catherine M

    2013-03-01

    The purpose of this ex post facto correlational study was to compare exit examination scores and NCLEX-RN(®) pass rates of baccalaureate nursing students who differed in level of participation in a standardized test package. Three cohort groups emerged as a standardized test package was introduced: (a) students who did not participate in a standardized test package; (b) students with two semesters of a standardized test package; and (c) students with four semesters of a standardized test package. Benner's novice-to-expert theory framed the study in the belief that students best acquire knowledge and skills through practice and reflection. Students participating in four semesters of a standardized test package demonstrated higher exit examination scores and NCLEX-RN pass rates compared with students who did not participate in this package. This study's results could inform nurse educators about strategies to facilitate nursing student success on exit examinations and the NCLEX-RN.

  4. Inertia effects on strategy updating in emergency evacuation from a room with multiple exits

    NASA Astrophysics Data System (ADS)

    Zhao, Yang; Li, Yuanzhen

    2014-03-01

    The inertia effects on strategy updating in emergency evacuation from a room with multiple exits is studied using the modified floor field model. Game theory is adopted to deal with conflict resolving process of evacuees and inertia effects are introduced in both exit choosing and conflict resolving process. From simulation results, the influences of inertia effects on the evacuation times and cooperation frequencies have been discussed. Interestingly, it can be found that inertia effects in exit choosing may lead more evacuation times, while inertia effects in conflict resolving may lead more evacuation times and higher cooperation frequencies. This study provides a new perspective to understand how the inertia of changing status quo acts on the strategy evolution in emergency circumstances.

  5. Ionization Time and Exit Momentum in Strong-Field Tunnel Ionization.

    PubMed

    Teeny, Nicolas; Yakaboylu, Enderalp; Bauke, Heiko; Keitel, Christoph H

    2016-02-12

    Tunnel ionization belongs to the fundamental processes of atomic physics. The so-called two-step model, which describes the ionization as instantaneous tunneling at the electric field maximum and classical motion afterwards with zero exit momentum, is commonly employed to describe tunnel ionization in adiabatic regimes. In this contribution, we show by solving numerically the time-dependent Schrödinger equation in one dimension and employing a virtual detector at the tunnel exit that there is a nonvanishing positive time delay between the electric field maximum and the instant of ionization. Moreover, we find a nonzero exit momentum in the direction of the electric field. To extract proper tunneling times from asymptotic momentum distributions of ionized electrons, it is essential to incorporate the electron's initial momentum in the direction of the external electric field.

  6. Mechanisms regulating phosphatase specificity and the removal of individual phosphorylation sites during mitotic exit.

    PubMed

    Rogers, Samuel; McCloy, Rachael; Watkins, D Neil; Burgess, Andrew

    2016-07-01

    Entry into mitosis is driven by the activity of kinases, which phosphorylate over 7000 proteins on multiple sites. For cells to exit mitosis and segregate their genome correctly, these phosphorylations must be removed in a specific temporal order. This raises a critical and important question: how are specific phosphorylation sites on an individual protein removed? Traditionally, the temporal order of dephosphorylation was attributed to decreasing kinase activity. However, recent evidence in human cells has identified unique patterns of dephosphorylation during mammalian mitotic exit that cannot be fully explained by the loss of kinase activity. This suggests that specificity is determined in part by phosphatases. In this review, we explore how the physicochemical properties of an individual phosphosite and its surrounding amino acids can affect interactions with a phosphatase. These positive and negative interactions in turn help determine the specific pattern of dephosphorylation required for correct mitotic exit. PMID:27417119

  7. Peritonitis and catheter exit-site infection in patients on peritoneal dialysis at home1

    PubMed Central

    Abud, Ana Cristina Freire; Kusumota, Luciana; dos Santos, Manoel Antônio; Rodrigues, Flávia Fernanda Luchetti; Damasceno, Marta Maria Coelho; Zanetti, Maria Lúcia

    2015-01-01

    Objective: to analyze the complications related to peritonitis and catheter exit-site infections, in patients on peritoneal dialysis at home. Method: quantitative and cross-sectional study, carried out with 90 patients on peritoneal dialysis at home, in a municipality in the Northeast region of Brazil. For data collection, it was used two structured scripts and consultation on medical records. Descriptive analysis and comparison tests among independent groups were used, considering p<0.05 as level of statistical significance. Results: by comparing the frequency of peritonitis and the length of treatment, it was found that patients over two years of peritoneal dialysis were more likely to develop peritonitis (X²=6.39; p=0.01). The number of episodes of peritoneal catheter exit-site infection showed association with the length of treatment (U=224,000; p=0.015). Conclusion: peritonitis and catheter exit-site infection are associated with the length of treatment. PMID:26487141

  8. Consequences of Predicted or Actual Asteroid Impacts

    NASA Astrophysics Data System (ADS)

    Chapman, C. R.

    2003-12-01

    Earth impact by an asteroid could have enormous physical and environmental consequences. Impactors larger than 2 km diameter could be so destructive as to threaten civilization. Since such events greatly exceed any other natural or man-made catastrophe, much extrapolation is necessary just to understand environmental implications (e.g. sudden global cooling, tsunami magnitude, toxic effects). Responses of vital elements of the ecosystem (e.g. agriculture) and of human society to such an impact are conjectural. For instance, response to the Blackout of 2003 was restrained, but response to 9/11 terrorism was arguably exaggerated and dysfunctional; would society be fragile or robust in the face of global catastrophe? Even small impacts, or predictions of impacts (accurate or faulty), could generate disproportionate responses, especially if news media reports are hyped or inaccurate or if responsible entities (e.g. military organizations in regions of conflict) are inadequately aware of the phenomenology of small impacts. Asteroid impact is the one geophysical hazard of high potential consequence with which we, fortunately, have essentially no historical experience. It is thus important that decision makers familiarize themselves with the hazard and that society (perhaps using a formal procedure, like a National Academy of Sciences study) evaluate the priority of addressing the hazard by (a) further telescopic searches for dangerous but still-undiscovered asteroids and (b) development of mitigation strategies (including deflection of an oncoming asteroid and on- Earth civil defense). I exemplify these issues by discussing several representative cases that span the range of parameters. Many of the specific physical consequences of impact involve effects like those of other geophysical disasters (flood, fire, earthquake, etc.), but the psychological and sociological aspects of predicted and actual impacts are distinctive. Standard economic cost/benefit analyses may not

  9. Prediction of outlet flow characteristics of centrifugal impellers. I - Consideration of velocity distortion

    NASA Astrophysics Data System (ADS)

    Kurokawa, J.; Hode, S.

    1985-07-01

    An analytical method for predicting the outlet flow characteristics from a centrifugal impeller is proposed. The method takes hub-to-shroud and blade-to-blade velocity distortion into consideration, and its usefulness is confirmed by measurements with pump impellers. It is concluded that, in calculating the theoretical head coefficient and the slip factor from the measured velocity of the absolute flow at the impeller outlet, the mass-averaged velocity of the section should be used. To get satisfactory prediction of the outlet flow characteristics, the increment of the wall shearing stress near the inlet of the parallel-walled diffuser channel due to the nonuniform flow must be considered. The influence of velocity distortion in the hub-to-shroud direction should be considered when the parallel-walled diffuser width is larger than the impeller exit width.

  10. Entrainment in High-Velocity, High Temperature Plasma Jets Part I: Experimental Results

    SciTech Connect

    Fincke, J.R.; Crawford, D.M.; Snyder, S.C.; Swank, W.D.; Haggard, D.C.; Williamson, R.L.

    2002-03-27

    The development of a high-velocity, high-temperature argon plasma jet issuing into air has been investigated. In particular the entrainment of the surrounding air, its effect on the temperature and velocity profiles and the subsequent mixing and dissociation of oxygen has been examined in detail. The total concentration of oxygen and the velocity and temperature profiles in the jet were obtained from an enthalpy probe. High-resolution Thomson scattering provided an independent measure of plasma velocity and temperature, validating enthalpy probe measurements and providing non-intrusive measurements near the nozzle exit. The concentration of atomic oxygen was obtained from two-photon Laser Induced Fluorescence (LIF). Molecular oxygen concentration and temperature was obtained from Coherent Anti-Stokes Raman Spectroscopy (CARS). It was found that both the incompleteness of mixing at the molecular scale and the rate of oxygen dissociation and recombination effects jet behavior.

  11. The Molecular Chaperone Hsp90 Is Required for Cell Cycle Exit in Drosophila melanogaster

    PubMed Central

    Bandura, Jennifer L.; Jiang, Huaqi; Nickerson, Derek W.; Edgar, Bruce A.

    2013-01-01

    The coordination of cell proliferation and differentiation is crucial for proper development. In particular, robust mechanisms exist to ensure that cells permanently exit the cell cycle upon terminal differentiation, and these include restraining the activities of both the E2F/DP transcription factor and Cyclin/Cdk kinases. However, the full complement of mechanisms necessary to restrain E2F/DP and Cyclin/Cdk activities in differentiating cells are not known. Here, we have performed a genetic screen in Drosophila melanogaster, designed to identify genes required for cell cycle exit. This screen utilized a PCNA-miniwhite+ reporter that is highly E2F-responsive and results in a darker red eye color when crossed into genetic backgrounds that delay cell cycle exit. Mutation of Hsp83, the Drosophila homolog of mammalian Hsp90, results in increased E2F-dependent transcription and ectopic cell proliferation in pupal tissues at a time when neighboring wild-type cells are postmitotic. Further, these Hsp83 mutant cells have increased Cyclin/Cdk activity and accumulate proteins normally targeted for proteolysis by the anaphase-promoting complex/cyclosome (APC/C), suggesting that APC/C function is inhibited. Indeed, reducing the gene dosage of an inhibitor of Cdh1/Fzr, an activating subunit of the APC/C that is required for timely cell cycle exit, can genetically suppress the Hsp83 cell cycle exit phenotype. Based on these data, we propose that Cdh1/Fzr is a client protein of Hsp83. Our results reveal that Hsp83 plays a heretofore unappreciated role in promoting APC/C function during cell cycle exit and suggest a mechanism by which Hsp90 inhibition could promote genomic instability and carcinogenesis. PMID:24086162

  12. The molecular chaperone Hsp90 is required for cell cycle exit in Drosophila melanogaster.

    PubMed

    Bandura, Jennifer L; Jiang, Huaqi; Nickerson, Derek W; Edgar, Bruce A

    2013-01-01

    The coordination of cell proliferation and differentiation is crucial for proper development. In particular, robust mechanisms exist to ensure that cells permanently exit the cell cycle upon terminal differentiation, and these include restraining the activities of both the E2F/DP transcription factor and Cyclin/Cdk kinases. However, the full complement of mechanisms necessary to restrain E2F/DP and Cyclin/Cdk activities in differentiating cells are not known. Here, we have performed a genetic screen in Drosophila melanogaster, designed to identify genes required for cell cycle exit. This screen utilized a PCNA-miniwhite(+) reporter that is highly E2F-responsive and results in a darker red eye color when crossed into genetic backgrounds that delay cell cycle exit. Mutation of Hsp83, the Drosophila homolog of mammalian Hsp90, results in increased E2F-dependent transcription and ectopic cell proliferation in pupal tissues at a time when neighboring wild-type cells are postmitotic. Further, these Hsp83 mutant cells have increased Cyclin/Cdk activity and accumulate proteins normally targeted for proteolysis by the anaphase-promoting complex/cyclosome (APC/C), suggesting that APC/C function is inhibited. Indeed, reducing the gene dosage of an inhibitor of Cdh1/Fzr, an activating subunit of the APC/C that is required for timely cell cycle exit, can genetically suppress the Hsp83 cell cycle exit phenotype. Based on these data, we propose that Cdh1/Fzr is a client protein of Hsp83. Our results reveal that Hsp83 plays a heretofore unappreciated role in promoting APC/C function during cell cycle exit and suggest a mechanism by which Hsp90 inhibition could promote genomic instability and carcinogenesis. PMID:24086162

  13. The velocity distribution of cometary hydrogen - Evidence for high velocities?

    NASA Technical Reports Server (NTRS)

    Brown, Michael E.; Spinrad, Hyron

    1993-01-01

    The Hamilton Echelle spectrograph on the 3-m Shane telescope at Lick Observatory was used to obtain high-velocity and spatial resolution 2D spectra of H-alpha 6563-A emission in Comets Austin and Levy. The presence of the components expected from water dissociation and collisional thermalization in the inner coma is confirmed by the hydrogen velocity distribution. In Comet Austin, the potential high-velocity hydrogen includes velocities of up to about 40 km/s and is spatially symmetric with respect to the nucleus. In Comet Levy, the high-velocity hydrogen reaches velocities of up to 50 km/s and is situated exclusively on the sunward side of the nucleus. The two distinct signatures of high-velocity hydrogen imply two distinct sources.

  14. Distinction between entrance and exit wounds by energy dispersive X-ray fluorescence spectrometry.

    PubMed

    Tanaka, Naoko; Kinoshita, Hiroshi; Takakura, Ayaka; Jamal, Mostofa; Ito, Asuka; Kumihashi, Mitsuru; Tsutsui, Kunihiko; Kimura, Shoji; Ameno, Kiyoshi

    2016-09-01

    We investigated gunshot wounds in two autopsy cases using energy dispersive X-ray spectrometry (EDX). Lead and copper were detected in the entrance wound of one case and lead, antimony, and copper were detected in that of the other case. In the exit wounds of both cases, lead, antimony, and copper were below detection limits. These findings indicate that the detection of metallic elements, such as lead, antimony, and copper, which are found in bullets, may be useful for differentiating entrance from exit wounds using EDX. PMID:27591531

  15. STS-102 crew gets emergency exit training at Launch Pad 39B during TCDT

    NASA Technical Reports Server (NTRS)

    2001-01-01

    KENNEDY SPACE CENTER, Fla. -- During emergency exit training on the Fixed Service Structure of Launch Pad 39B, STS-102 Mission Specialist Paul Richards takes a closer look at the lever that releases a slidewire basket, used for emergency exits from the launch pad, to the landing below. He and the rest of the crew are taking part in Terminal Countdown Demonstration Test activities, which include a simulated launch countdown. STS-102 is the eighth construction flight to the International Space Station, with Space Shuttle Discovery carrying the Multi-Purpose Logistics Module Leonardo. Launch on mission STS-102 is scheduled for March 8.

  16. Plasma arc welding torch having means for vortexing plasma gas exiting the welding torch

    NASA Technical Reports Server (NTRS)

    Rybicki, Daniel J. (Inventor); Mcgee, William F. (Inventor)

    1994-01-01

    A plasma arc welding torch is described wherein a plasma gas is directed through the body of the welding torch and out of the body across the tip of the welding electrode disposed at the forward end of the body. The plasma gas is provided with a vortexing motion prior to exiting the body by a vortex motion imparting member which is mounted in an orifice housing member and carried in the forward portion of the torch body. The orifice housing member is provided with an orifice of an predetermined diameter through which the electric arc and the plasma gas exits.

  17. Unitaxial constant velocity microactuator

    DOEpatents

    McIntyre, Timothy J.

    1994-01-01

    A uniaxial drive system or microactuator capable of operating in an ultra-high vacuum environment. The mechanism includes a flexible coupling having a bore therethrough, and two clamp/pusher assemblies mounted in axial ends of the coupling. The clamp/pusher assemblies are energized by voltage-operated piezoelectrics therewithin to operatively engage the shaft and coupling causing the shaft to move along its rotational axis through the bore. The microactuator is capable of repeatably positioning to sub-manometer accuracy while affording a scan range in excess of 5 centimeters. Moreover, the microactuator generates smooth, constant velocity motion profiles while producing a drive thrust of greater than 10 pounds. The system is remotely controlled and piezoelectrically driven, hence minimal thermal loading, vibrational excitation, or outgassing is introduced to the operating environment.

  18. Unitaxial constant velocity microactuator

    DOEpatents

    McIntyre, T.J.

    1994-06-07

    A uniaxial drive system or microactuator capable of operating in an ultra-high vacuum environment is disclosed. The mechanism includes a flexible coupling having a bore therethrough, and two clamp/pusher assemblies mounted in axial ends of the coupling. The clamp/pusher assemblies are energized by voltage-operated piezoelectrics therewithin to operatively engage the shaft and coupling causing the shaft to move along its rotational axis through the bore. The microactuator is capable of repeatably positioning to sub-nanometer accuracy while affording a scan range in excess of 5 centimeters. Moreover, the microactuator generates smooth, constant velocity motion profiles while producing a drive thrust of greater than 10 pounds. The system is remotely controlled and piezoelectrically driven, hence minimal thermal loading, vibrational excitation, or outgassing is introduced to the operating environment. 10 figs.

  19. Velocity specificity, combination training and sport specific tasks.

    PubMed

    Cronin, J; McNair, P J; Marshall, R N

    2001-06-01

    Whether velocity-specific resistance training is important for improving functional sporting performance was investigated by studying the effect of isoinertial training velocity on netball chest pass throwing velocity. Twenty-one female netball players were randomly assigned to a strength-trained group (80% 1RM - average training velocity = .308 m/s), power-trained group (60% 1RM - average training velocity = .398 m/s) and a control group. Resistance training was combined with sport specific motion training for both groups over a ten-week training duration. Pre- and post-training testing revealed that the training velocity associated with the strength-trained group produced significantly greater improvement in mean volume of weight lifted (85kg) and mean power output (13.25 W) as compared to the power and control groups (P< 0.05). The strength-trained and power-trained groups significantly improved netball throw velocity by 12.4% and 8.8% respectively. There was no significant difference between the two groups. The validity of velocity-specific training and subsequent adaptations to improve functional sporting performance appears highly questionable, due to the disparity between training velocity and actual movement velocity (11.38 m x s(-1)) for a given sport specific task such as the netball throw it was proposed that the repeated intent to move an isoinertial load as rapidly as possible coupled with performance of the sport-specific movement promote efficient coordination and activation patterns. Such mechanisms might be more important determinants of sport-specific high velocity adaptation.

  20. Dependence of kinetic friction on velocity: master equation approach.

    PubMed

    Braun, O M; Peyrard, M

    2011-04-01

    We investigate the velocity dependence of kinetic friction with a model that makes minimal assumptions on the actual mechanism of friction so that it can be applied at many scales, provided the system involves multicontact friction. Using a recently developed master equation approach, we investigate the influence of two concurrent processes. First, at a nonzero temperature, thermal fluctuations allow an activated breaking of contacts that are still below the threshold. As a result, the friction force monotonically increases with velocity. Second, the aging of contacts leads to a decrease of the friction force with velocity. Aging effects include two aspects: the delay in contact formation and aging of a contact itself, i.e., the change of its characteristics with the duration of stationary contact. All these processes are considered simultaneously with the master equation approach, giving a complete dependence of the kinetic friction force on the driving velocity and system temperature, provided the interface parameters are known.

  1. 40 CFR 74.22 - Actual SO2 emissions rate.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 17 2012-07-01 2012-07-01 false Actual SO2 emissions rate. 74.22... (CONTINUED) SULFUR DIOXIDE OPT-INS Allowance Calculations for Combustion Sources § 74.22 Actual SO2 emissions... actual SO2 emissions rate shall be 1985. (2) For combustion sources that commenced operation...

  2. Actualization and the Fear of Death: Retesting an Existential Hypothesis.

    ERIC Educational Resources Information Center

    Wood, Keith; Robinson, Paul J.

    1982-01-01

    Demonstrates that within a group of highly actualized individuals, the degree to which "own death" is integrated into constructs of self is a far more powerful predictor of fear of death than actualization. Findings suggest that actualization and integration are independent in their overall effect on fear of death. (Author)

  3. Detection of velocity in high temperature liquid metals

    NASA Technical Reports Server (NTRS)

    Mikrovas, A. C.; Argyropoulos, S. A.

    1993-01-01

    Various efforts have been made to measure velocity in liquid metals. All of these efforts, however, share the same inherent limitation, namely, not being operative at the high temperatures required by liquid metals and liquid slags in an industrial application. In this paper, the current methods used were reviewed, and a new technique was presented for the measurement of velocity in high temperature liquid metals. In using this technique there are two stages. Starting with the calibration stage and then moving to the actual measurement stage by making use of the data obtained from calibration stage. Calibration proceeds in the following manner. Metallic spheres moving with a specific velocity are immersed in liquid metal held under isothermal conditions and at specific temperature. Their melting times are determined very accurately with a novel technique. These measurements are repeated for different metal bath temperatures and for different velocities of metallic spheres. In this manner it is possible to calculate the correlation between velocity and melting times for each metal bath temperature. During the actual measurement stage, when the metal bath temperature is known and its velocity is unknown, the magnitude of the unknown liquid metal velocity can be derived as follows: metallic spheres are immersed into the moving liquid metal and their melting times are determined. Using the above mentioned correlations, it will be shown that the magnitude of the unknown velocity in liquid metal can be deduced. This new technique was applied to high temperature liquid aluminum and liquid steel and these results were presented. The potential applicability of this technique in other liquid metals and liquid slags will also be discussed.

  4. Exploring Work and Development Options to Reduce Early Labour Force Exit of Mature Aged Australians

    ERIC Educational Resources Information Center

    Pillay, Hitendra; Kelly, Kathy; Tones, Megan

    2008-01-01

    Early labour force exit is a significant challenge associated with the ageing workforce in Australia and many other developed countries. A reduction and increased flexibility of work hours has been suggested to improve labour force participation of the mature aged cohort. However, little is known about mature aged workers' aspirations for…

  5. Compulsory Literacy and Numeracy Exit Standards for Senior Secondary Students: The Right Direction for Australia?

    ERIC Educational Resources Information Center

    Rice, Suzanne; Care, Esther; Griffin, Patrick

    2012-01-01

    An overview of positive and negative potential effects of the setting of compulsory exit-level standards in literacy and numeracy for students completing their final years of schooling is presented. The overview rests on studies completed primarily outside Australia, reflecting the reality of such practices not having been implemented widely in…

  6. Is the Resolution Style "Exiting Statements" Related to Adolescent Problem Behavior?

    ERIC Educational Resources Information Center

    Wijsbroek, Saskia A. M.; Hale, William W., III; Van Doorn, Muriel D.; Raaijmakers, Quinten A. W.; Meeus, Wim H. J.

    2010-01-01

    This study examined the association between the adolescents' conflict resolution style "exiting statements" (i.e., the expression of the adolescent' desire to minimize or end the contact with his or her parents) in parent-adolescent conflicts with self-rated adolescent GAD symptoms and delinquency symptoms of 1313 adolescents. A multi-group,…

  7. Marking emergency exits and evacuation routes with sound beacons utilizing the precedence effect

    NASA Astrophysics Data System (ADS)

    van Wijngaarden, Sander J.; Bronkhorst, Adelbert W.; Boer, Louis C.

    2001-05-01

    Sound beacons can be extremely useful during emergency evacuations, especially when vision is obscured by smoke. When exits are marked with suitable sound sources, people can find these using only their capacity for directional hearing. Unfortunately, unless very explicit instructions were given, sound beacons currently commercially available (based on modulated noise) led to disappointing results during an evacuation experiment in a traffic tunnel. Only 19% out of 65 subjects were able to find an exit by ear. A signal designed to be more self-explanatory and less hostile-sounding (alternating chime signal and spoken message ``exit here'') increased the success rate to 86%. In a more complex environment-a mock-up of a ship's interior-routes to the exit were marked using multiple beacons. By applying carefully designed time delays between successive beacons, the direction of the route was marked, utilizing the precedence effect. Out of 34 subjects, 71% correctly followed the evacuation route by ear (compared to 24% for a noise signal as used in commercially available beacons). Even when subjects were forced to make a worst-case left-right decision at a T-junction, between two beacons differing only in arrival of the first wave front, 77% made the right decision.

  8. Quantifying groundwater dependency of riparian surface hydrologic features using the exit gradient

    EPA Science Inventory

    This study examines groundwater exit gradients as a way to quantify groundwater interactions with surface water. We calibrated high resolution groundwater models for the basin fill sediments in the lower Calapooia watershed, Oregon, using data collected between 1928--2000. The e...

  9. Predicting Success, Preventing Failure: An Investigation of the California High School Exit Exam

    ERIC Educational Resources Information Center

    Zau, Andrew C.; Betts, Julian R.

    2008-01-01

    Many educators, parents, and policymakers continue to call for reforms to the California High School Exit Exam (CAHSEE), citing concern about the 10 percent of California students who do not graduate because of their failure to pass the test. By law, current funding for tutoring those at risk of failing the CAHSEE is targeted at those in grade 12…

  10. Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21Cip1

    PubMed Central

    Trakala, Marianna; Fernández-Miranda, Gonzalo; Pérez de Castro, Ignacio; Heeschen, Christopher; Malumbres, Marcos

    2013-01-01

    Aurora kinase B is a critical component of the chromosomal passenger complex, which is involved in the regulation of microtubule-kinetochore attachments and cytokinesis. By using conditional knockout cells and chemical inhibition, we show here that inactivation of Aurora B results in delayed G1/S transition and premature mitotic exit. Aurora B deficiency results in delayed DNA replication in cultured fibroblasts as well as liver cells after hepatectomy. This is accompanied by increased transcription of the cell cycle inhibitor p21Cip1. Lack of Aurora B does not prevent mitotic entry but results in a premature exit from prometaphase in the presence of increased p21Cip1-Cdk1 inactive complexes. Aurora B-null cells display reduced degradation of cyclin B1, suggesting the presence of phenomenon known as adaptation to the mitotic checkpoint, previously described in yeast. Elimination of p21Cip1 rescues Cdk1 activity and prevents premature mitotic exit in Aurora B-deficient cells. These results suggest that Aurora B represses p21Cip1, preventing delayed DNA replication, Cdk inhibition and premature mitotic exit. The upregulation of p21Cip1 observed after inhibition of Aurora B may have important implications in cell cycle progression, tetraploidy, senescence or cancer therapy. PMID:23428904

  11. High precision measurements of atom column positions using model-based exit wave reconstruction.

    PubMed

    De Backer, A; Van Aert, S; Van Dyck, D

    2011-01-01

    In this paper, it has been investigated how to measure atom column positions as accurately and precisely as possible using a focal series of images. In theory, it is expected that the precision would considerably improve using a maximum likelihood estimator based on the full series of focal images. As such, the theoretical lower bound on the variances of the unknown atom column positions can be attained. However, this approach is numerically demanding. Therefore, maximum likelihood estimation has been compared with the results obtained by fitting a model to a reconstructed exit wave rather than to the full series of focal images. Hence, a real space model-based exit wave reconstruction technique based on the channelling theory is introduced. Simulations show that the reconstructed complex exit wave contains the same amount of information concerning the atom column positions as the full series of focal images. Only for thin samples, which act as weak phase objects, this information can be retrieved from the phase of the reconstructed complex exit wave.

  12. The Entrance and Exit Effects in Small Electrochemical Filter-Press Reactors Used in the Laboratory

    ERIC Educational Resources Information Center

    Frias-Ferrer, Angel; Gonzalez-Garcia, Jose; Saez, Veronica; Exposito, Eduardo; Sanchez-Sanchez, Carlos M.; Mantiel, Vicente; Walsh, Frank C.; Aldaz, Antonio; Walsh, Frank C.

    2005-01-01

    A laboratory experiment designed to examine the entrance and exit effects in small electrochemical filter-press reactors used in the laboratory is presented. The single compartment of the filter-press reactor is filled with different turbulence promoters to study their influence as compared to the empty configuration.

  13. Cholesterol is required in the exit pathway of Semliki Forest virus

    PubMed Central

    1993-01-01

    The enveloped alphavirus Semliki Forest virus (SFV) infects cells via a membrane fusion reaction triggered by low pH. For fusion to occur cholesterol is required in the target membrane, as demonstrated both in in vitro fusion assays and in vivo for virus infection of a host cell. In this paper we examine the role of cholesterol in postfusion events in the SFV life cycle. Cholesterol-depleted insect cells were transfected with SFV RNA or infected at very high multiplicities to circumvent the fusion block caused by the absence of cholesterol. Under these conditions, the viral spike proteins were synthesized and transported to the site of p62 cleavage with normal kinetics. Surprisingly, the subsequent exit of virus particles was dramatically slowed compared to cholesterol-containing cells. The inhibition of virus production could be reversed by the addition of cholesterol to depleted cells. In contrast to results with SFV, no cholesterol requirement for virus exit was observed for the production of either the unrelated vesicular stomatitis virus or a cholesterol-independent SFV fusion mutant. Thus, cholesterol was only critical in the exit pathway of viruses that also require cholesterol for fusion. These results demonstrate a specific and unexpected lipid requirement in virus exit, and suggest that in addition to its role in fusion, cholesterol is involved in the assembly or budding of SFV. PMID:8408205

  14. 24 CFR 3280.106 - Exit facilities; egress windows and devices.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Planning Considerations... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Exit facilities; egress windows and devices. 3280.106 Section 3280.106 Housing and Urban Development Regulations Relating to Housing and...

  15. 24 CFR 3280.106 - Exit facilities; egress windows and devices.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Planning Considerations... 24 Housing and Urban Development 5 2012-04-01 2012-04-01 false Exit facilities; egress windows and devices. 3280.106 Section 3280.106 Housing and Urban Development Regulations Relating to Housing and...

  16. Ethnic variations in immigrant poverty exit and female employment: the missing link.

    PubMed

    Kaida, Lisa

    2015-04-01

    Despite widespread interest in poverty among recent immigrants and female immigrant employment, research on the link between the two is limited. This study evaluates the effect of recently arrived immigrant women's employment on the exit from family poverty and considers the implications for ethnic differences in poverty exit. It uses the bivariate probit model and the Fairlie decomposition technique to analyze data from the Longitudinal Survey of Immigrants to Canada (LSIC), a nationally representative survey of immigrants arriving in Canada, 2000-2001. Results show that the employment of recently arrived immigrant women makes a notable contribution to lifting families out of poverty. Moreover, the wide ethnic variations in the probability of exit from poverty between European and non-European groups are partially explained by the lower employment rates among non-European women. The results suggest that the equal earner/female breadwinner model applies to low-income recent immigrant families in general, but the male breadwinner model explains the low probability of poverty exit among select non-European groups whose female employment rates are notably low.

  17. 49 CFR 571.217 - Standard No. 217; Bus emergency exits and window retention and release.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... the List of CFR Sections Affected, which appears in the Finding Aids section of the printed volume and... Figure 3D(1) and Figure 3D(2) for an interior release mechanism for a rear emergency exit door, and within the high force access region shown in Figure 3D(1) for an exterior release mechanism for a...

  18. Exit and Entry: Why Parents in Utah Left Public Schools and Chose Private Schools

    ERIC Educational Resources Information Center

    Bukhari, Patras; Randall, E. Vance

    2009-01-01

    This study explored the factors that influenced parental decisions to exit a public school and enroll their children in a private school. It also explored why parents chose the specific private school their child attends and the level of satisfaction they have with their private school choice. The key reasons for leaving public education were: (a)…

  19. Pedestrian overpass at West 176th Street, over Riverside Drive exit, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Pedestrian overpass at West 176th Street, over Riverside Drive exit, connecting Haven Avenue to Fort Washington Park. George Washington Bridge in background, looking north. - Henry Hudson Parkway, Extending 11.2 miles from West 72nd Street to Bronx-Westchester border, New York County, NY

  20. Irreversibility of mitotic exit is the consequence of systems level feedback

    PubMed Central

    López-Avilés, Sandra; Kapuy, Orsolya; Novák, Béla; Uhlmann, Frank

    2009-01-01

    The eukaryotic cell cycle comprises an ordered series of events, orchestrated by the activity of cyclin-dependent kinases (Cdks), leading from chromosome replication during S-phase to their segregation in mitosis. The unidirectionality of cell cycle transitions is fundamental for successful completion of this cycle. It is thought that irrevocable proteolytic degradation of key cell cycle regulators makes cell cycle transitions irreversible, thereby enforcing directionality1-3. Here, we have experimentally examined the contribution of cyclin proteolysis to the irreversibility of mitotic exit, the transition from high mitotic Cdk activity back to low activity in G1. We show that forced cyclin destruction in mitotic budding yeast cells efficiently drives mitotic exit events. However, these remain reversible after termination of cyclin proteolysis, with recovery of the mitotic state and cyclin levels. Mitotic exit becomes irreversible only after longer periods of cyclin degradation, due to activation of a double-negative feedback loop involving the Cdk inhibitor Sic1 (refs 4​,​5). Quantitative modelling suggests that feedback is required to maintain low Cdk activity and to prevent cyclin resynthesis. Our findings demonstrate that unidirectionality of mitotic exit is not the consequence of proteolysis but of systems level feedback required to maintain the cell cycle in a new stable state. PMID:19387440

  1. A Mathematical Model of Mitotic Exit in Budding Yeast: The Role of Polo Kinase

    PubMed Central

    Hancioglu, Baris; Tyson, John J.

    2012-01-01

    Cell cycle progression in eukaryotes is regulated by periodic activation and inactivation of a family of cyclin–dependent kinases (Cdk's). Entry into mitosis requires phosphorylation of many proteins targeted by mitotic Cdk, and exit from mitosis requires proteolysis of mitotic cyclins and dephosphorylation of their targeted proteins. Mitotic exit in budding yeast is known to involve the interplay of mitotic kinases (Cdk and Polo kinases) and phosphatases (Cdc55/PP2A and Cdc14), as well as the action of the anaphase promoting complex (APC) in degrading specific proteins in anaphase and telophase. To understand the intricacies of this mechanism, we propose a mathematical model for the molecular events during mitotic exit in budding yeast. The model captures the dynamics of this network in wild-type yeast cells and 110 mutant strains. The model clarifies the roles of Polo-like kinase (Cdc5) in the Cdc14 early anaphase release pathway and in the G-protein regulated mitotic exit network. PMID:22383977

  2. Exit Counseling Guide for Counselors. William D. Ford Federal Direct Loan Program.

    ERIC Educational Resources Information Center

    Department of Education, Washington, DC.

    This guide is intended to help school financial aid administrators meet the requirement that they provide in-person exit counseling to borrowers of Federal Direct Stafford/Ford Loans (direct subsidized) and Federal Direct Unsubsidized Stafford/Ford Loans (direct unsubsidized). The guide is intended to be used with a companion video and a guide for…

  3. MTR, TRA603. FOUNDATION PLAN, SECTION C THROUGH COOLANT WATER EXIT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    MTR, TRA-603. FOUNDATION PLAN, SECTION C THROUGH COOLANT WATER EXIT TUNNEL ALONG NORTH SIDE AS IT RETURNS TO MAIN COOLANT TUNNEL LEAVING BUILDING TO THE NORTH. BLAW-KNOX 3150-803-35, 5/1950. INL INDEX NO. 531-0603-62-098-100591, REV. 2. - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  4. Non-bulk-like solvent behavior in the ribosome exit tunnel.

    PubMed

    Lucent, Del; Snow, Christopher D; Aitken, Colin Echeverría; Pande, Vijay S

    2010-10-21

    As nascent proteins are synthesized by the ribosome, they depart via an exit tunnel running through the center of the large subunit. The exit tunnel likely plays an important part in various aspects of translation. Although water plays a key role in many bio-molecular processes, the nature of water confined to the exit tunnel has remained unknown. Furthermore, solvent in biological cavities has traditionally been characterized as either a continuous dielectric fluid, or a discrete tightly bound molecule. Using atomistic molecular dynamics simulations, we predict that the thermodynamic and kinetic properties of water confined within the ribosome exit tunnel are quite different from this simple two-state model. We find that the tunnel creates a complex microenvironment for the solvent resulting in perturbed rotational dynamics and heterogenous dielectric behavior. This gives rise to a very rugged solvation landscape and significantly retarded solvent diffusion. We discuss how this non-bulk-like solvent is likely to affect important biophysical processes such as sequence dependent stalling, co-translational folding, and antibiotic binding. We conclude with a discussion of the general applicability of these results to other biological cavities.

  5. Aircraft and avionic related research required to develop an effective high-speed runway exit system

    NASA Technical Reports Server (NTRS)

    Schoen, M. L.; Hosford, J. E.; Graham, J. M., Jr.; Preston, O. W.; Frankel, R. S.; Erickson, J. B.

    1979-01-01

    Research was conducted to increase airport capacity by studying the feasibility of the longitudinal separation between aircraft sequences on final approach. The multidisciplinary factors which include the utility of high speed exits for efficient runway operations were described along with recommendations and highlights of these studies.

  6. Comparing Virtual Reference Exit Survey Results and Transcript Analysis: A Model for Service Evaluation

    ERIC Educational Resources Information Center

    Smyth, Joanne B.; MacKenzie, James C.

    2006-01-01

    This study uses virtual reference transcripts for which patrons completed exit surveys to seek any correlations between user and librarian satisfaction within virtual reference transactions. By analyzing transcripts with a focus on three elements-technology performance, preferred reference practices, and the demonstrated communication levels of…

  7. Passing the California High School Exit Exam: Have Recent Policies Improved Student Performance?

    ERIC Educational Resources Information Center

    Betts, Julian R.; Zau, Andrew C.; Zieleniak, Yendrick; Bachofer, Karen Volz

    2012-01-01

    The California High School Exit Examination (CAHSEE) plays an important role in California's public school accountability program. Beginning in grade 10, students have multiple chances to pass the mathematics and English Language Arts components of this exam. If they do not pass both components by the end of grade 12, they will not receive a high…

  8. Teaching Better, Teaching Together: A Coordinated Student Exit Poll across the States

    ERIC Educational Resources Information Center

    Emery, Jennifer Kelkres; Howard, Alison; Evans, Jocelyn

    2014-01-01

    Student exit polling has demonstrated value in the classroom (Berry and Robinson 2012; Evans and Lagergren 2007; Lelieveldt and Rossen 2009), but faculty typically operate these polls in isolation. When faculty collaborate, however, students gain additional benefits from the experience. Collaboration provides a geographically diverse "student…

  9. 77 FR 19132 - Federal Motor Vehicle Safety Standards; Bus Emergency Exits and Window Retention and Release

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-30

    ... (NPRM) upon which this final rule is based was published on December 28, 2009 (74 FR 68558) (Docket No... application to release the exit.'' The language first appeared in a November 2, 1992 final rule (57 FR 49423... August 12, 2005 final rule (70 FR 47131), we amended FMVSS No. 217 by, among other things,...

  10. Making Sense of Exit Exam Policies: A Phenomenological Study of English Language Development Teachers

    ERIC Educational Resources Information Center

    Forrest, Scott N.

    2010-01-01

    There is a lack of understanding regarding how sensemaking could be incorporated into a professional development program to improve teacher quality and student achievement. The lived experiences of high school English language development teachers as they interpret English language development and one state's high school exit exam instructional…

  11. "Now My Old Self Is Thin": Stigma Exits after Weight Loss

    ERIC Educational Resources Information Center

    Granberg, Ellen M.

    2011-01-01

    In this article, I employ a structural symbolic interaction framework to examine the processes by which persons can exit a stigmatized identity. Using the empirical example of weight loss, I analyze how individuals evolve from an identity as "fat" and stigmatized to one that is "normal" with respect to weight and free from identification with…

  12. 49 CFR 571.217 - Standard No. 217; Bus emergency exits and window retention and release.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... its occupant space is not more than 10 inches from an emergency exit, for a distance of at least 15... rearmost limits of the passenger compartment. Occupant space means the space directly above the seat and... nearest obstruction of occupant motion in the direction the seat faces. Passenger compartment means...

  13. Ceramic filters and their use for cleaning dust-laden hot exit gases

    SciTech Connect

    B.L. Krasnyi; V.P. Tarasovskii; A.Yu. Val'dberg

    2005-03-01

    The performance characteristics of ceramic filter cells for cleaning dust-laden hot exit gases (400 - 1000{sup o}C) are reported. Major process parameters of a newly designed module-type FKI-45 filtering unit fitted with ceramic filter cells are given.

  14. STS-44 crewmembers exit people mover after landing at EAFB, California

    NASA Technical Reports Server (NTRS)

    1991-01-01

    STS-44 crewmembers, wearing launch and entry suits (LESs), exit people mover, a crew transport vehicle, after landing at Edwards Air Force Base (EAFB), California. Commander Frederick D. Gregory follows ground crew personnel down the stairway. Gregory leads Mission Specialist (MS) Mario Runco, Jr, and Payload Specialist Thomas J. Hennen. In the background, is Atlantis, Orbiter Vehicle (OV) 104, undergoing post flight servicing.

  15. Exit Documents and Students with Disabilities: Legal Issues. EPRRI Issue Brief Two.

    ERIC Educational Resources Information Center

    Karger, Joanne; Pullin, Diana

    This report describes court challenges to high school exit exams for students with disabilities, explores the legal and public policy issues, and discusses implications for educators. Legal challenges include claims brought under the Due Process and Equal Protection clauses of the Fourteenth Amendment, and under disability statutes, including the…

  16. Existential Group Therapy as a Treatment Modality for Exiting Christian Fundamentalists.

    ERIC Educational Resources Information Center

    Brent, John S.

    1991-01-01

    Suggests that existential concepts can be useful in group therapy with exiting Christian Fundamentalists. Defines fundamentalism and discusses the human dilemma from the existential perspective. Proposes ways of applying existential principles as an alternative to fundamentalist interpretations of being, anxiety, crisis, and freedom and…

  17. Prevalence of Gender DIF in Mixed Format High School Exit Examinations.

    ERIC Educational Resources Information Center

    Henderson, Dianne L.

    The primary purpose of this study was to identify potential sources of gender differential item bias (DIF) in a high school exit examination composed of both selected-response and constructed-response items in the content areas of English, social studies, mathematics, and biology. A secondary purpose was to determine the agreement between the…

  18. Impact of Repeatedly Failing a High School Exit Exam: Voices of English Language Learners

    ERIC Educational Resources Information Center

    Kruger, Louis J.; Li, Chieh; Kimble, Edward; Ruah, Rachel; Stoianov, Diana; Krishnan, Kalyani

    2016-01-01

    This qualitative study explored the perceived psychological impact of repeated failures on a high school exit examination (HSEE). We interviewed eight self-identified English language learners (ELLs), whose ages ranged from 20 to 29. All participants were attending tutoring HSEE programs at urban community colleges in New England. Using a modified…

  19. Causal Factors Attributed to Student Success on the California High School Exit Examination

    ERIC Educational Resources Information Center

    Rose, Nikita A.

    2011-01-01

    American students are failing to demonstrate expected competency on basic skills taught in schools. The educational system needs a major overhaul to address declines in scholarly engagement. The State Board of Education (SBE) designed the California High School Exit Exam (CAHSEE) to give some merit to the high school diploma. Minorities and…

  20. Why do some employees fall into and fail to exit a job-lock situation?

    PubMed

    Huysse-Gaytandjieva, Anna; Groot, Wim; Pavlova, Milena

    2013-01-01

    Previous studies have paid little attention to the employees' ability to exit a job-lock situation and factors that determine this ability. It remains unclear why some employees who experience job lock are able to exit this state while others remain in job lock. We use longitudinal data to identify employees who have fallen in the state of job lock and their subsequent behavior-exiting or remaining in job lock. By use of a first-order Markov transition models, we analyze the relevance of sociodemographic features, employment, occupational, sectoral, and contextual factors, as well as personality characteristics in explaining the transition or its absence. Overall the results show that both demographic factors and work-related aspects increase the likelihood that an employee enters the long-term job lock state (especially for older, married, full-time employed, those in a craft occupation and governmental sector, and in a region with high unemployment). Mental health problems and personality characteristics (low peak-end self-esteem and decisional procrastination) have a significant effect on the probability to stay in long-term job lock. On the contrary, having a managerial, service, or associate occupation, working in the private sector, and having promotion opportunities increase the chance of an exit from the state of job lock. PMID:23737809

  1. Children's Reading Profiles on Exiting the Reading Recovery Programme: Do They Predict Sustained Progress?

    ERIC Educational Resources Information Center

    Holliman, Andrew J.; Hurry, Jane; Bodman, Sue

    2016-01-01

    The aim of this study was to identify reading profiles, which predict the literacy progress of Reading Recovery graduates. Reading Recovery is an intensive remediation for children after the first year of school. Children were assessed at exit from the programme and at 3-month, 6-month and 12-month follow-up points. Text Reading Level made unique…

  2. PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells

    PubMed Central

    Rogers, Samuel; Fey, Dirk; McCloy, Rachael A.; Parker, Benjamin L.; Mitchell, Nicholas J.; Payne, Richard J.; Daly, Roger J.; James, David E.; Caldon, C. Elizabeth; Watkins, D. Neil; Croucher, David R.; Burgess, Andrew

    2016-01-01

    ABSTRACT Entry into mitosis is driven by the phosphorylation of thousands of substrates, under the master control of Cdk1. During entry into mitosis, Cdk1, in collaboration with MASTL kinase, represses the activity of the major mitotic protein phosphatases, PP1 and PP2A, thereby ensuring mitotic substrates remain phosphorylated. For cells to complete and exit mitosis, these phosphorylation events must be removed, and hence, phosphatase activity must be reactivated. This reactivation of phosphatase activity presumably requires the inhibition of MASTL; however, it is not currently understood what deactivates MASTL and how this is achieved. In this study, we identified that PP1 is associated with, and capable of partially dephosphorylating and deactivating, MASTL during mitotic exit. Using mathematical modelling, we were able to confirm that deactivation of MASTL is essential for mitotic exit. Furthermore, small decreases in Cdk1 activity during metaphase are sufficient to initiate the reactivation of PP1, which in turn partially deactivates MASTL to release inhibition of PP2A and, hence, create a feedback loop. This feedback loop drives complete deactivation of MASTL, ensuring a strong switch-like activation of phosphatase activity during mitotic exit. PMID:26872783

  3. Leaving Welfare: Differences between Those Who Exited Voluntarily and Those Who Stayed

    ERIC Educational Resources Information Center

    Santhiveeran, Janaki; Jimenez, Jillian

    2004-01-01

    This article uses data from the National Longitudinal Survey of Youth 1979-1998 to understand the differences between those who exited the welfare system voluntarily (leavers) and those who stayed (non-leavers), 1990-1996. The purpose of this research was to examine the differences between the groups in their personal and family characteristics,…

  4. Exit and Voice: Turnover and Militancy Intentions in Elementary and Secondary Schools.

    ERIC Educational Resources Information Center

    Bacharach, Samuel B.; Bamberger, Peter

    1990-01-01

    Using Hirschman's conception of exit (turnover) and voice (militancy) as employee responses to objectionable working conditions, this article examines the degree to which teacher job satisfaction and stress symptomology and two hypothesized antecedents (role conflict and ambiguity) are likely to have the same effect on voicing and exiting…

  5. Quality Assurance in Higher Education Institutions: Exit Survey among Universiti Putra Malaysia Graduating Students

    ERIC Educational Resources Information Center

    Konting, Mohd Majid; Kamaruddin, Norfaryanti; Man, Nor Azirawani

    2009-01-01

    This paper presents the exit survey of graduating students at Universiti Putra Malaysia (UPM). The results gathered from 1,823 final year students of the 2006/07 session indicate that overall, the students' satisfaction level is moderately high (3.55 ± 0.79). The students' perception on the attributes of graduates resulting from learning outcomes…

  6. School Exits in the Milwaukee Parental Choice Program: Evidence of a Marketplace?

    ERIC Educational Resources Information Center

    Ford, Michael

    2011-01-01

    This article examines whether the large number of school exits from the Milwaukee school voucher program is evidence of a marketplace. Two logistic regression and multinomial logistic regression models tested the relation between the inability to draw large numbers of voucher students and the ability for a private school to remain viable. Data on…

  7. Hydrokinetic canal measurements: inflow velocity, wake flow velocity, and turbulence

    DOE Data Explorer

    Gunawan, Budi

    2014-06-11

    The dataset consist of acoustic Doppler current profiler (ADCP) velocity measurements in the wake of a 3-meter diameter vertical-axis hydrokinetic turbine deployed in Roza Canal, Yakima, WA, USA. A normalized hub-centerline wake velocity profile and two cross-section velocity contours, 10 meters and 20 meters downstream of the turbine, are presented. Mean velocities and turbulence data, measured using acoustic Doppler velocimeter (ADV) at 50 meters upstream of the turbine, are also presented. Canal dimensions and hydraulic properties, and turbine-related information are also included.

  8. Particle Velocity Measuring System

    NASA Technical Reports Server (NTRS)

    Arndt, G. Dickey (Inventor); Carl, James R. (Inventor)

    1998-01-01

    Method and apparatus are provided for determining the velocity of individual food particles within a liquid/solid food mixture that is cooked by an aseptic cooking method whereby the food mixture is heated as it flows through a flowline. At least one upstream and at least one downstream microwave transducer are provided to determine the minimum possible travel time of the fastest food particle through the flowline. In one embodiment, the upstream detector is not required. In another embodiment, a plurality of small dipole antenna markers are secured to a plurality of food particles to provide a plurality of signals as the markers pass the upstream and downstream transducers. The dipole antenna markers may also include a non-linear element to reradiate a harmonic frequency of a transmitter frequency. Upstream and downstream transducers include dipole antennas that are matched to the impedance of the food slurry and a signal transmission cable by various impedance matching means including unbalanced feed to the antennas.

  9. Velocity dependant splash behaviour

    NASA Astrophysics Data System (ADS)

    Hamlett, C. A. E.; Shirtcliffe, N. J.; McHale, G.; Ahn, S.; Doerr, S. H.; Bryant, R.; Newton, M. I.

    2012-04-01

    Extreme soil water repellency can occur in nature via condensation of volatile organic compounds released during wildfires and can lead to increased erosion rate. Such extreme water repellent soil can be classified as superhydrophobic and shares similar chemical and topographical features to specifically designed superhydrophobic surfaces. Previous studies using high speed videography to investigate single droplet impact behaviour on artificial superhydrophobic have revealed three distinct modes of splash behaviour (rebound, pinned and fragmentation) which are dependent on the impact velocity of the droplet. In our studies, using high-speed videography, we show that such splash behaviour can be replicated on fixed 'model' water repellent soils (hydrophobic glass beads/particles). We show that the type of splash behaviour is dependent on both the size and chemical nature of the fixed particles. The particle shape also influences the splash behaviour as shown by drop impact experiments on fixed sand samples. We have also studied soil samples, as collected from the field, which shows that the type of droplet splash behaviour can lead to enhanced soil particle transport.

  10. Influence of speckle effect on doppler velocity measurement

    NASA Astrophysics Data System (ADS)

    Zheng, Zheng; Changming, Zhao; Haiyang, Zhang; Suhui, Yang; Dehua, Zhang; Xingyuan, Zheng; Hongzhi, Yang

    2016-06-01

    In a coherent Lidar system, velocity measurement of a target is achieved by measuring Doppler frequency shift between the echo and local oscillator (LO) signals. The measurement accuracy is proportional to the spectrum width of Doppler signal. Actually, the speckle effect caused by the scattering of laser from a target will broaden the Doppler signal's spectrum and bring uncertainty to the velocity measurement. In this paper, a theoretical model is proposed to predict the broadening of Doppler spectrum with respect to different target's surface and motion parameters. The velocity measurement uncertainty caused by the broadening of spectrum is analyzed. Based on the analysis, we design a coherent Lidar system to measure the velocity of the targets with different surface roughness and transverse velocities. The experimental results are in good agreement with theoretical analysis. It is found that the target's surface roughness and transverse velocity can significantly affect the spectrum width of Doppler signal. With the increase of surface roughness and transverse velocity, the measurement accuracy becomes worse. However, the influence of surface roughness becomes weaker when the spot size of laser beam on the target is smaller.

  11. 75 FR 48412 - Proposed Information Collection (Six-Month Post-Exit Focus Interview of Former VHA Employees...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF VETERANS AFFAIRS Proposed Information Collection (Six-Month Post-Exit Focus Interview of Former VHA Employees.... 2900-New (VA Form 10-0487).'' SUPPLEMENTARY INFORMATION: Title: Six-Month Post-Exit Focus Interview...

  12. 10 CFR 431.204 - Uniform test method for the measurement of energy consumption of illuminated exit signs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Uniform test method for the measurement of energy consumption of illuminated exit signs. 431.204 Section 431.204 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION... Procedures § 431.204 Uniform test method for the measurement of energy consumption of illuminated exit...

  13. 10 CFR 431.204 - Uniform test method for the measurement of energy consumption of illuminated exit signs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Uniform test method for the measurement of energy consumption of illuminated exit signs. 431.204 Section 431.204 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION... Procedures § 431.204 Uniform test method for the measurement of energy consumption of illuminated exit...

  14. Velocity Dispersions Across Bulge Types

    SciTech Connect

    Fabricius, Maximilian; Bender, Ralf; Hopp, Ulrich; Saglia, Roberto; Drory, Niv; Fisher, David

    2010-06-08

    We present first results from a long-slit spectroscopic survey of bulge kinematics in local spiral galaxies. Our optical spectra were obtained at the Hobby-Eberly Telescope with the LRS spectrograph and have a velocity resolution of 45 km/s (sigma*), which allows us to resolve the velocity dispersions in the bulge regions of most objects in our sample. We find that the velocity dispersion profiles in morphological classical bulge galaxies are always centrally peaked while the velocity dispersion of morphologically disk-like bulges stays relatively flat towards the center--once strongly barred galaxies are discarded.

  15. Ion velocities in the presheath of electronegative, radio-frequency plasmas measured by low-energy cutoff

    NASA Astrophysics Data System (ADS)

    Sobolewski, Mark A.; Wang, Yicheng; Goyette, Amanda

    2016-07-01

    Simple kinematic considerations indicate that, under certain conditions in radio-frequency (rf) plasmas, the amplitude of the low-energy peak in ion energy distributions (IEDs) measured at an electrode depends sensitively on ion velocities upstream, at the presheath/sheath boundary. By measuring this amplitude, the velocities at which ions exit the presheath can be determined and long-standing controversies regarding presheath transport can be resolved. Here, IEDs measured in rf-biased, inductively coupled plasmas in CF4 gas determined the presheath exit velocities of all significant positive ions: CF3+, CF2+, CF+, and F+. At higher bias voltages, we detected essentially the same velocity for all four ions. For all ions, measured velocities were significantly lower than the Bohm velocity and the electropositive ion sound speed. Neither is an accurate boundary condition for rf sheaths in electronegative gases: under certain low-frequency, high-voltage criteria defined here, either yields large errors in predicted IEDs. These results indicate that many widely used sheath models will need to be revised.

  16. Velocity ratio and its application to predicting velocities

    USGS Publications Warehouse

    Lee, Myung W.

    2003-01-01

    The velocity ratio of water-saturated sediment derived from the Biot-Gassmann theory depends mainly on the Biot coefficient?a property of dry rock?for consolidated sediments with porosity less than the critical porosity. With this theory, the shear moduli of dry sediments are the same as the shear moduli of water-saturated sediments. Because the velocity ratio depends on the Biot coefficient explicitly, Biot-Gassmann theory accurately predicts velocity ratios with respect to differential pressure for a given porosity. However, because the velocity ratio is weakly related to porosity, it is not appropriate to investigate the velocity ratio with respect to porosity (f). A new formulation based on the assumption that the velocity ratio is a function of (1?f)n yields a velocity ratio that depends on porosity, but not on the Biot coefficient explicitly. Unlike the Biot-Gassmann theory, the shear moduli of water-saturated sediments depend not only on the Biot coefficient but also on the pore fluid. This nonclassical behavior of the shear modulus of water-saturated sediment is speculated to be an effect of interaction between fluid and the solid matrix, resulting in softening or hardening of the rock frame and an effect of velocity dispersion owing to local fluid flow. The exponent n controls the degree of softening/hardening of the formation. Based on laboratory data measured near 1 MHz, this theory is extended to include the effect of differential pressure on the velocity ratio by making n a function of differential pressure and consolidation. However, the velocity dispersion and anisotropy are not included in the formulation.

  17. Sodium Velocity Maps on Mercury

    NASA Technical Reports Server (NTRS)

    Potter, A. E.; Killen, R. M.

    2011-01-01

    The objective of the current work was to measure two-dimensional maps of sodium velocities on the Mercury surface and examine the maps for evidence of sources or sinks of sodium on the surface. The McMath-Pierce Solar Telescope and the Stellar Spectrograph were used to measure Mercury spectra that were sampled at 7 milliAngstrom intervals. Observations were made each day during the period October 5-9, 2010. The dawn terminator was in view during that time. The velocity shift of the centroid of the Mercury emission line was measured relative to the solar sodium Fraunhofer line corrected for radial velocity of the Earth. The difference between the observed and calculated velocity shift was taken to be the velocity vector of the sodium relative to Earth. For each position of the spectrograph slit, a line of velocities across the planet was measured. Then, the spectrograph slit was stepped over the surface of Mercury at 1 arc second intervals. The position of Mercury was stabilized by an adaptive optics system. The collection of lines were assembled into an images of surface reflection, sodium emission intensities, and Earthward velocities over the surface of Mercury. The velocity map shows patches of higher velocity in the southern hemisphere, suggesting the existence of sodium sources there. The peak earthward velocity occurs in the equatorial region, and extends to the terminator. Since this was a dawn terminator, this might be an indication of dawn evaporation of sodium. Leblanc et al. (2008) have published a velocity map that is similar.

  18. Factors associated with biosafety level-2 research workers' laboratory exit handwashing behaviors and glove removal compliance.

    PubMed

    Johnston, James D; Merrill, Ray M; Zimmerman, Grant C; Collingwood, Scott C; Reading, James C

    2016-01-01

    Biosafety level-2 laboratories are designated for work with human-derived samples or moderate-risk microorganisms that transmit primarily by direct contact exposures. Many laboratory procedures generate unseen droplets that contaminate workers' hands, equipment, and work surfaces. Workers' strict adherence to glove removal and handwashing is required prior to laboratory exit to prevent inadvertent transmission of pathogens to self or others. However, little is known about biosafety level-2 workers' compliance with these behaviors. In this article, glove removal and handwashing compliance upon laboratory exit were measured by direct observation of 93 biosafety level-2 research workers from 21 university laboratories. Participants completed a 41-item survey measuring social cognitive theory-based variables related to handwashing, self-reported compliance, and demographic factors. Survey items, observed exit frequency, and laboratory characteristics were evaluated for associations with handwashing compliance. Overall, observed glove removal and handwashing compliance upon laboratory exit were 43.0% (Standard Error [SE] = 2.3%), and 8.2% (SE = 1.2%), respectively, while workers' self-reported glove removal and handwashing compliance were 73.7% (SE = 3.6%) and 35.5% (SE = 4.1%), respectively. The average number of observed laboratory exits per hour was 2.8 for workers with any handwashing compliance vs. 5.4 for workers with no handwashing compliance (p = 0.0013). Among the cognitive variables, behavioral modeling by supervisors and coworkers had the strongest association with workers' compliance (slope = 3.5, SE = 1.3, p = 0.0113). Workers in laboratories with a written handwashing policy had higher compliance (Mean = 14.1%, SE = 5.9%) than workers in laboratories with no written policy (Mean = 1.1%, SE = 1.0%; p = 0.0488). Multi-faceted interventions that encourage modeling of the behavior by supervisors and coworkers, implementation of written handwashing policies

  19. Relationship between perceived and actual motor competence among college students.

    PubMed

    Wang, Jianyu; Liu, Wenhao; Bian, Wei

    2013-02-01

    The relationship between perceived and actual motor competence was examined among college students. Participants were 114 college students (55 men, 59 women; M age = 22.3 yr., SD = 3.9). All participants completed a short survey on perception of motor competence in basketball and took a Control Basketball Dribble Test to assess their actual motor skill. Perceived motor competence in basketball was significantly related to basketball dribbling performance. Given the positive relationship between actual motor competence and perceived competence, enhancing an individual's actual motor competence may contribute to their perceived competence, which may improve an individual's physical activity participation.

  20. Multi-Velocity Component LDV

    NASA Technical Reports Server (NTRS)

    Johnson, Dennis A. (Inventor)

    1996-01-01

    A laser doppler velocimeter uses frequency shifting of a laser beam to provide signal information for each velocity component. A composite electrical signal generated by a light detector is digitized and a processor produces a discrete Fourier transform based on the digitized electrical signal. The transform includes two peak frequencies corresponding to the two velocity components.

  1. Instantaneous Velocity Using Photogate Timers

    ERIC Educational Resources Information Center

    Wolbeck, John

    2010-01-01

    Photogate timers are commonly used in physics laboratories to determine the velocity of a passing object. In this application a card attached to a moving object breaks the beam of the photogate timer providing the time for the card to pass. The length L of the passing card can then be divided by this time to yield the average velocity (or speed)…

  2. Definition of Contravariant Velocity Components

    NASA Technical Reports Server (NTRS)

    Hung, Ching-Mao; Kwak, Dochan (Technical Monitor)

    2002-01-01

    This is an old issue in computational fluid dynamics (CFD). What is the so-called contravariant velocity or contravariant velocity component? In the article, we review the basics of tensor analysis and give the contravariant velocity component a rigorous explanation. For a given coordinate system, there exist two uniquely determined sets of base vector systems - one is the covariant and another is the contravariant base vector system. The two base vector systems are reciprocal. The so-called contravariant velocity component is really the contravariant component of a velocity vector for a time-independent coordinate system, or the contravariant component of a relative velocity between fluid and coordinates, for a time-dependent coordinate system. The contravariant velocity components are not physical quantities of the velocity vector. Their magnitudes, dimensions, and associated directions are controlled by their corresponding covariant base vectors. Several 2-D (two-dimensional) linear examples and 2-D mass-conservation equation are used to illustrate the details of expressing a vector with respect to the covariant and contravariant base vector systems, respectively.

  3. Exit Strategy

    ERIC Educational Resources Information Center

    Harac, Lani

    2006-01-01

    While many teachers have district-funded pensions that are the envy of their counterparts in other professions, the reality is that most must still augment their retirement savings. Yet K-12 educators and administrators are often uninformed about how to invest wisely. In this article, the author relates how former educator Dan Otter discovered…

  4. Early Exit.

    ERIC Educational Resources Information Center

    Fogg, Piper

    2002-01-01

    Using the example of the University of Massachusetts at Amherst, discusses how the economic downturn is prompting states and university systems to offer faculty members big incentives to retire, raising questions about effects on the quality of teaching. Includes a sidebar on other prominent retirees. (EV)

  5. Velocity Field Measurements of Human Coughing Using Time Resolved Particle Image Velocimetry

    NASA Astrophysics Data System (ADS)

    Khan, T.; Marr, D. R.; Higuchi, H.; Glauser, M. N.

    2003-11-01

    Quantitative fluid mechanics analysis of human coughing has been carried out using new Time Resolved Particle Image Velocimetry (TRPIV). The study involves measurement of velocity vector time-histories and velocity profiles. It is focused on the average normal human coughing. Some work in the past on cough mechanics has involved measurement of flow rates, tidal volumes and sub-glottis pressure. However, data of unsteady velocity vector field of the exiting highly time-dependent jets is not available. In this study, human cough waveform data are first acquired in vivo using conventional respiratory instrumentation for various volunteers of different gender/age groups. The representative waveform is then reproduced with a coughing/breathing simulator (with or without a manikin) for TRPIV measurements and analysis. The results of this study would be useful not only for designing of indoor air quality and heating, ventilation and air conditioning systems, but also for devising means of protection against infectious diseases.

  6. PLK1 regulation of PCNT cleavage ensures fidelity of centriole separation during mitotic exit

    PubMed Central

    Kim, Jaeyoun; Lee, Kwanwoo; Rhee, Kunsoo

    2015-01-01

    Centrioles are duplicated and segregated in close link to the cell cycle. During mitosis, daughter centrioles are disengaged and eventually separated from mother centrioles. New daughter centrioles may be generated only after centriole separation. Therefore, centriole separation is considered a licensing step for centriole duplication. It was previously known that separase specifically cleaves pericentrin (PCNT) during mitotic exit. Here we report that PCNT has to be phosphorylated by PLK1 to be a suitable substrate of separase. Phospho-resistant mutants of PCNT are not cleaved by separase and eventually inhibit centriole separation. Furthermore, phospho-mimetic PCNT mutants rescue centriole separation even in the presence of a PLK1 inhibitor. On the basis on these results, we propose that PLK1 phosphorylation is a priming step for separase-mediated cleavage of PCNT and eventually for centriole separation. PLK1 phosphorylation of PCNT provides an additional layer of regulatory mechanism to ensure the fidelity of centriole separation during mitotic exit. PMID:26647647

  7. Focus Groups and Exit Interviews Are Components of Chemistry Department Program Assessment

    NASA Astrophysics Data System (ADS)

    Dreisbach, Joseph H.; Hogan, Thomas P.; Stamford, Anne Marie; Greggo, John W.

    1998-10-01

    The Chemistry Department, in conjunction with the Assessment and Institutional Research Office (AIRO) and the Department of Counseling and Human Services developed an assessment plan which incorporates use of focus groups and exit interviews. As part of the five-year departmental review, a number of student focus groups were facilitated to evaluate (a) the freshman and sophomore organic chemistry programs which also service other departments and (b) the upper division lecture and laboratory program for majors. Use of direct conversation in program assessment yields less ambiguous results compared with other methods because responses can be clarified with careful follow up questions. Success of this project gave rise to use of annual exit interviews with graduating seniors from the chemistry department. The approach described can easily be modified to meet the needs of any academic setting.

  8. Systematic drug perturbations on cancer cells reveal diverse exit paths from proliferative state.

    PubMed

    Zhou, Joseph X; Isik, Zerrin; Xiao, Caide; Rubin, Irit; Kauffman, Stuart A; Schroeder, Michael; Huang, Sui

    2016-02-16

    During a cell state transition, cells travel along trajectories in a gene expression state space. This dynamical systems framework complements the traditional concept of molecular pathways that drive cell phenotype switching. To expose the structure that hinders cancer cells from exiting robust proliferative state, we assessed the perturbation capacity of a drug library and identified 16 non-cytotoxic compounds that stimulate MCF7 breast cancer cells to exit from proliferative state to differentiated state. The transcriptome trajectories triggered by these drugs diverged, then converged. Chemical structures and drug targets of these compounds overlapped minimally. However, a network analysis of targeted pathways identified a core signaling pathway--indicating common stress-response and down-regulation of STAT1 before differentiation. This multi-trajectory analysis explores the cells' state transition with a multitude of perturbations in combination with traditional pathway analysis, leading to an encompassing picture of the dynamics of a therapeutically desired cell-state switching.

  9. Bistability of mitotic entry and exit switches during open mitosis in mammalian cells.

    PubMed

    Hégarat, Nadia; Rata, Scott; Hochegger, Helfrid

    2016-07-01

    Mitotic entry and exit are switch-like transitions that are driven by the activation and inactivation of Cdk1 and mitotic cyclins. This simple on/off reaction turns out to be a complex interplay of various reversible reactions, feedback loops, and thresholds that involve both the direct regulators of Cdk1 and its counteracting phosphatases. In this review, we summarize the interplay of the major components of the system and discuss how they work together to generate robustness, bistability, and irreversibility. We propose that it may be beneficial to regard the entry and exit reactions as two separate reversible switches that are distinguished by differences in the state of phosphatase activity, mitotic proteolysis, and a dramatic rearrangement of cellular components after nuclear envelope breakdown, and discuss how the major Cdk1 activity thresholds could be determined for these transitions. PMID:27231150

  10. Entrance and exit region friction factor models for annular seal analysis. Ph.D. Thesis

    NASA Technical Reports Server (NTRS)

    Elrod, David Alan

    1988-01-01

    The Mach number definition and boundary conditions in Nelson's nominally-centered, annular gas seal analysis are revised. A method is described for determining the wall shear stress characteristics of an annular gas seal experimentally. Two friction factor models are developed for annular seal analysis; one model is based on flat-plate flow theory; the other uses empirical entrance and exit region friction factors. The friction factor predictions of the models are compared to experimental results. Each friction model is used in an annular gas seal analysis. The seal characteristics predicted by the two seal analyses are compared to experimental results and to the predictions of Nelson's analysis. The comparisons are for smooth-rotor seals with smooth and honeycomb stators. The comparisons show that the analysis which uses empirical entrance and exit region shear stress models predicts the static and stability characteristics of annular gas seals better than the other analyses. The analyses predict direct stiffness poorly.

  11. Systematic drug perturbations on cancer cells reveal diverse exit paths from proliferative state

    PubMed Central

    Xiao, Caide; Rubin, Irit; Kauffman, Stuart A.; Schroeder, Michael; Huang, Sui

    2016-01-01

    During a cell state transition, cells travel along trajectories in a gene expression state space. This dynamical systems framework complements the traditional concept of molecular pathways that drive cell phenotype switching. To expose the structure that hinders cancer cells from exiting robust proliferative state, we assessed the perturbation capacity of a drug library and identified 16 non-cytotoxic compounds that stimulate MCF7 breast cancer cells to exit from proliferative state to differentiated state. The transcriptome trajectories triggered by these drugs diverged, then converged. Chemical structures and drug targets of these compounds overlapped minimally. However, a network analysis of targeted pathways identified a core signaling pathway - indicating common stress-response and down-regulation of STAT1 before differentiation. This multi-trajectory analysis explores the cells' state transition with a multitude of perturbations in combination with traditional pathway analysis, leading to an encompassing picture of the dynamics of a therapeutically desired cell-state switching. PMID:26871731

  12. Exit Dose Measurement in Therapeutic High Energy Photon Beams and Cobalt-60 Gamma Rays

    NASA Astrophysics Data System (ADS)

    Sathiyan, S.; Ravikumar, M.

    2007-01-01

    To estimate the skin dose to the patient from the treatment planning, the knowledge about exit dose is essential, which is calculated from the percentage depth dose. In this study 6 MV and 18 MV beams from linear accelerator and cobalt-60 beams were used. The ionometric measurements were carried out with parallel plate chamber of sensitive volume 0.16 cc. Parallel plate chamber was fitted in to 30 x 30 cm2 polystyrene phantom at a fixed FSD with the measuring entrance window facing farther from the source. The field size for this measuring condition was maintained at 10 x 10 cm2. The ionization measurements were also carried out by changing the thickness of the polystyrene phantom at the entrance side of the point of measurement. In order to find out the variation of relative exit dose (RED) with field size the measurements were carried out without and with the full back-scattering material (27.2 gm/cm2) placed beyond the entrance window of the chamber. The measurements were also done for the entrance polystyrene phantom thicknesses of 10, 20 and 30 cm for the field size ranging from 5 x 5 cm2 to 30 x 30 cm2. The dose at the exit surface with no backscatter material is about 4.4%, 3.7% and 5.8% less than the dose with the full backscatter material present beyond the point of measurement for 6 MV, 18 MV X-rays and cobalt-60 gamma rays. The reduction in exit dose does not depend much of the phantom thickness through which the beam traverses before exiting at the chamber side. Dose enhancements of about 1.03 times were observed for a field size of 5 x 5 cm2 for 6 MV, 18 MV X-rays and cobalt-60 gamma rays. The dose enhancement factor (DEF) values were noticed to vary with field size beyond 15 x 15 cm2 for all the energies studied. Also it can be observed that the dose enhancement factor (DEF) values do not depend on the thickness of the phantom material through which the beam has traversed. The DEF values were found to vary marginally for different phantom material

  13. PLK1 regulation of PCNT cleavage ensures fidelity of centriole separation during mitotic exit.

    PubMed

    Kim, Jaeyoun; Lee, Kwanwoo; Rhee, Kunsoo

    2015-12-09

    Centrioles are duplicated and segregated in close link to the cell cycle. During mitosis, daughter centrioles are disengaged and eventually separated from mother centrioles. New daughter centrioles may be generated only after centriole separation. Therefore, centriole separation is considered a licensing step for centriole duplication. It was previously known that separase specifically cleaves pericentrin (PCNT) during mitotic exit. Here we report that PCNT has to be phosphorylated by PLK1 to be a suitable substrate of separase. Phospho-resistant mutants of PCNT are not cleaved by separase and eventually inhibit centriole separation. Furthermore, phospho-mimetic PCNT mutants rescue centriole separation even in the presence of a PLK1 inhibitor. On the basis on these results, we propose that PLK1 phosphorylation is a priming step for separase-mediated cleavage of PCNT and eventually for centriole separation. PLK1 phosphorylation of PCNT provides an additional layer of regulatory mechanism to ensure the fidelity of centriole separation during mitotic exit.

  14. Design, durability and low cost processing technology for composite fan exit guide vanes

    NASA Technical Reports Server (NTRS)

    Blecherman, S. S.

    1980-01-01

    A program was conducted to design, fabricate and test a durable, low cost, lightweight composite fan exit guide vane for high bypass ratio gas turbine engine application. Eight candidate material/design combinations were evaluated by NASTRAN finite element analysis. Four of these candidate systems were selected for composite vane fabrication by two vendors. A core and shell vane design was chosen in which the unidirectional graphite core fiber was the same for all candidates. The shell material, fiber orientation and ply configuration were varied. Material tests were performed on raw material and composite specimens to establish specification requirements. Composite vanes were nondestructively inspected and subsequently fatigue tested in both dry and 'wet' conditions. The program provided relevant data with respect to design analysis, materials properties, inspection standards, improved durability, weight benefits and part price of the composite fan exit guide vane.

  15. Showing Where To Go by Maps or Pictures: An Empirical Case Study at Subway Exits

    NASA Astrophysics Data System (ADS)

    Ishikawa, Toru; Yamazaki, Tetsuo

    This study empirically examined the effectiveness of different methods of presenting route information on a mobile navigation sysyem, for accurate and effortless orientation at subway exits. Specifically, it compared participants’ spatial orientation performance with pictures and maps, in relation to the levels of their spatial ability. Participants identified the directions toward the goals after coming onto the ground faster when viewing pictures than when viewing maps. Spatial orientation with maps was more difficult than that with pictures at exits where body rotation was necessary, especially for people with low mental-rotation ability. In contrast, pictures were equally effective for people with low and high mental-rotation ability. Reasons for the effectiveness of pictures and possibilities of using other presentation formats are discussed.

  16. Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition.

    PubMed

    Singh, Shalini; Howell, Danielle; Trivedi, Niraj; Kessler, Ketty; Ong, Taren; Rosmaninho, Pedro; Raposo, Alexandre Asf; Robinson, Giles; Roussel, Martine F; Castro, Diogo S; Solecki, David J

    2016-05-14

    In the developing mammalian brain, differentiating neurons mature morphologically via neuronal polarity programs. Despite discovery of polarity pathways acting concurrently with differentiation, it's unclear how neurons traverse complex polarity transitions or how neuronal progenitors delay polarization during development. We report that zinc finger and homeobox transcription factor-1 (Zeb1), a master regulator of epithelial polarity, controls neuronal differentiation by transcriptionally repressing polarity genes in neuronal progenitors. Necessity-sufficiency testing and functional target screening in cerebellar granule neuron progenitors (GNPs) reveal that Zeb1 inhibits polarization and retains progenitors in their germinal zone (GZ). Zeb1 expression is elevated in the Sonic Hedgehog (SHH) medulloblastoma subgroup originating from GNPs with persistent SHH activation. Restored polarity signaling promotes differentiation and rescues GZ exit, suggesting a model for future differentiative therapies. These results reveal unexpected parallels between neuronal differentiation and mesenchymal-to-epithelial transition and suggest that active polarity inhibition contributes to altered GZ exit in pediatric brain cancers.

  17. Design, durability and low cost processing technology for composite fan exit guide vanes

    NASA Technical Reports Server (NTRS)

    Blecherman, S. S.

    1979-01-01

    A lightweight composite fan exit guide vane for high bypass ratio gas turbine engine application was investigated. Eight candidate material/design combinations were evaluated by NASTRAN finite element analyses. A total of four combinations were selected for further analytical evaluation, part fabrication by two ventors, and fatigue test in dry and wet condition. A core and shell vane design was chosen in which the unidirectional graphite core fiber was the same for all candidates. The shell material, fiber orientation, and ply configuration were varied. Material tests were performed on raw material and composite specimens to establish specification requirements. Pre-test and post-test microstructural examination and nondestructive analyses were conducted to determine the effect of material variations on fatigue durability and failure mode. Relevant data were acquired with respect to design analysis, materials properties, inspection standards, improved durability, weight benefits, and part price of the composite fan exit guide vane.

  18. No exit and the organization of voice in biotechnology and pharmaceuticals.

    PubMed

    Light, Donald W; Castellblanch, Ramón; Arredondo, Pablo; Socolar, Deborah

    2003-01-01

    Although leadership is typically seen as coming from the leaders of governments and major institutions, a strong case can be made that concerned citizens first articulate important issues and policies that official leaders then pick up and promote. In a market-based society dominated by large corporations, Hirschman's framework of exit, voice, and loyalty can be used to relate consumer and grassroots movements to markets, when participants believe there is no exit and loyalty (or acquiescence) is not an option. While "voice" is usually applied to the individual or consumer level, this article develops the concept of organized voice and illustrates how it has exhibited leadership in the controversial relations between the biotech and pharmaceutical industries and society as a whole. The essay concludes by urging more research on organized voice as a source of leadership and by outlining some important dimensions for researchers to consider.

  19. Convertion Shear Wave Velocity to Standard Penetration Resistance

    NASA Astrophysics Data System (ADS)

    Madun, A.; Tajuddin, S. A. A.; Abdullah, M. E.; Abidin, M. H. Z.; Sani, S.; Siang, A. J. L. M.; Yusof, M. F.

    2016-07-01

    Multichannel Analysis Surface Wave (MASW) measurement is one of the geophysics exploration techniques to determine the soil profile based on shear wave velocity. Meanwhile, borehole intrusive technique identifies the changes of soil layer based on soil penetration resistance, i.e. standard penetration test-number of blows (SPT-N). Researchers across the world introduced many empirical conversions of standard penetration test blow number of borehole data to shear wave velocity or vice versa. This is because geophysics test is a non-destructive and relatively fast assessment, and thus should be promoted to compliment the site investigation work. These empirical conversions of shear wave velocity to SPT-N blow can be utilised, and thus suitable geotechnical parameters for design purposes can be achieved. This study has demonstrated the conversion between MASW and SPT-N value. The study was conducted at the university campus and Sejagung Sri Medan. The MASW seismic profiles at the University campus test site and Sejagung were at a depth of 21 m and 13 m, respectively. The shear wave velocities were also calculated empirically using SPT-N value, and thus both calculated and measured shear wave velocities were compared. It is essential to note that the MASW test and empirical conversion always underestimate the actual shear wave velocity of hard layer or rock due to the effect of soil properties on the upper layer.

  20. South Atlantic Anomaly Entry and Exit as Measured by the X-Ray Timing Explorer

    NASA Technical Reports Server (NTRS)

    Smith, Evan; Stark, Michael; Giles, Barry; Antunes, Sandy; Gawne, Bill

    1996-01-01

    The Rossi X-ray Timing Explorer (RXTE) carries instruments that must switch off high voltages (HV) when passing through the South Atlantic Anomaly (SAA). The High Energy X-ray Timing Experiment (HEXTE) contains a particle monitor that detects the increased particle flux associated with the SAA and autonomously reduces its voltage. The Proportional Counter Array (PCA) relies on uplinked predictions of SAA entry/exit times based on ephemeris data provided by the Flight Dynamics Facility. A third instrument, the All-Sky Monitor (ASM) also uses a predicted SAA model to reduce voltage when passing through the SAA. Data collected from the HEXTE particle monitor, as well as other instrument readings near the times of SAA entry/exit offer the potential for refining models of the boundaries of the SAA. The SAA has an increased particle flux which causes high rates of detection in the RXTE instruments designed to observe x-rays. The high counting rates could degrade the PCA if HV is not reduced during SAA passages. On the other hand, PCA downtime can be minimized and the science return can be optimized by having the best possible model of the SAA boundary. Thus, the PCA team planned an extensive effort during in-orbit checkout to utilize both the HEXTE particle monitor data and instrument counting rates to refine the model of the SAA boundary. The times of SAA entry and exit are compared with the definitive epemeris to determine the precise location (latitude and longitude) of the SAA boundary. Over time, the SAA and its perimeter were mapped. The RXTE Science Operations Center is continuously working to feed back the results of this effort into the science scheduling process, improving the SAA model as it affects the RXTE instruments, thus obtaining more accurate estimates of the SAA entry/exit times.

  1. Synergistic Blockade of Mitotic Exit by Two Chemical Inhibitors of the APC/C

    PubMed Central

    Sackton, Katharine L.; Dimova, Nevena; Zeng, Xing; Tian, Wei; Zhang, Mengmeng; Sackton, Timothy B.; Meaders, Johnathan; Pfaff, Kathleen L.; Sigoillot, Frederic; Yu, Hongtao; Luo, Xuelian; King, Randall W.

    2014-01-01

    Summary Protein machines are multi-subunit protein complexes that orchestrate highly regulated biochemical tasks. An example is the Anaphase-Promoting Complex/Cyclosome (APC/C), a thirteen-subunit ubiquitin ligase that initiates the metaphase-anaphase transition and mitotic exit by targeting proteins such as securin and cyclin B1 for ubiquitin-dependent destruction by the proteasome1,2. Because blocking mitotic exit is an effective approach for inducing tumor cell death3,4, the APC/C represents a potential novel target for cancer therapy. APC/C activation in mitosis requires binding of Cdc205, which forms a co-receptor with the APC/C to recognize substrates containing a Destruction box (D-box)6-14. Here we demonstrate that we can synergistically inhibit APC/C-dependent proteolysis and mitotic exit by simultaneously disrupting two protein-protein interactions within the APC/C-Cdc20-substrate ternary complex. We identified a small molecule, called apcin (APC inhibitor), which binds to Cdc20 and competitively inhibits the ubiquitylation of D-box-containing substrates. Analysis of the crystal structure of the apcin-Cdc20 complex suggests that apcin occupies the D-box-binding pocket on the side face of the WD40-domain. The ability of apcin to block mitotic exit is synergistically amplified by co-addition of tosyl-L-arginine methyl ester (TAME), a small molecule that blocks the APC/C-Cdc20 interaction15,16. This work suggests that simultaneous disruption of multiple, weak protein-protein interactions is an effective approach for inactivating a protein machine. PMID:25156254

  2. Rotavirus entry: a deep journey into the cell with several exits.

    PubMed

    Arias, Carlos F; Silva-Ayala, Daniela; López, Susana

    2015-01-15

    Rotaviruses are the leading etiological agents of acute gastroenteritis in infants and young children worldwide. These nonenveloped viruses enter cells using different types of endocytosis and, depending on the virus strain, travel to different endosomal compartments before exiting to the cytosolic space. In this Gem, we review the viral and cellular factors involved in the different stages of a productive virus cell entry and share with the readers the journey that we have taken into the cell to learn about virus entry.

  3. Exit competencies in pathology and laboratory medicine for graduating medical students: the Canadian approach.

    PubMed

    Ford, Jason; Pambrun, Chantale

    2015-05-01

    Physicians in every medical and surgical field must be able to use pathology concepts and skills in their practice: for example, they must order and interpret the correct laboratory tests, they must use their understanding of pathogenesis to diagnose and treat, and they must work with the laboratory to care for their patients. These important concepts and skills may be ignored by medical schools and even national/international organizations setting graduation expectations for medical students. There is an evolving international consensus about the importance of exit competencies for medical school graduates, which define the measurable or observable behaviors each graduate must be able to demonstrate. The Canadian Association of Pathologists (CAP) Education Group set out to establish the basic competencies in pathology and laboratory medicine which should be expected of every medical graduate: not competencies for pathologists, but for medical graduates who intend to enter any residency program. We defined 4 targets for pathology and laboratory medicine exit competencies: that they represent only measurable behaviors, that they be clinically focused, that they be generalizable to every medical graduate, and that the final competency document be user-friendly. A set of competencies was developed iteratively and underwent final revision at the 2012 CAP annual meeting. These competencies were subsequently endorsed by the CAP executive and the Canadian Leadership Council on Laboratory Medicine. This clinically focused consensus document provides the first comprehensive list of exit competencies in pathology and laboratory medicine for undergraduate medical education. PMID:25776028

  4. Tumor Treating Fields Perturb the Localization of Septins and Cause Aberrant Mitotic Exit

    PubMed Central

    Holtzman, Talia S.; Lee, Sze Xian; Wong, Eric T.; Swanson, Kenneth D.

    2015-01-01

    The anti-tumor effects of chemotherapy and radiation are thought to be mediated by triggering G1/S or G2/M cell cycle checkpoints, while spindle poisons, such as paclitaxel, block metaphase exit by initiating the spindle assembly checkpoint. In contrast, we have found that 150 kilohertz (kHz) alternating electric fields, also known as Tumor Treating Fields (TTFields), perturbed cells at the transition from metaphase to anaphase. Cells exposed to the TTFields during mitosis showed normal progression to this point, but exhibited uncontrolled membrane blebbing that coincided with metaphase exit. The ability of such alternating electric fields to affect cellular physiology is likely to be dependent on their interactions with proteins possessing high dipole moments. The mitotic Septin complex consisting of Septin 2, 6 and 7, possesses a high calculated dipole moment of 2711 Debyes (D) and plays a central role in positioning the cytokinetic cleavage furrow, and governing its contraction during ingression. We showed that during anaphase, TTFields inhibited Septin localization to the anaphase spindle midline and cytokinetic furrow, as well as its association with microtubules during cell attachment and spreading on fibronectin. After aberrant metaphase exit as a consequence of TTFields exposure, cells exhibited aberrant nuclear architecture and signs of cellular stress including an overall decrease in cellular proliferation, followed by apoptosis that was strongly influenced by the p53 mutational status. Thus, TTFields are able to diminish cell proliferation by specifically perturbing key proteins involved in cell division, leading to mitotic catastrophe and subsequent cell death. PMID:26010837

  5. Effects of inlet distortion on gas turbine combustion chamber exit temperature profiles

    NASA Astrophysics Data System (ADS)

    Maqsood, Omar Shahzada

    Damage to a nozzle guide vane or blade, caused by non-uniform temperature distributions at the combustion chamber exit, is deleterious to turbine performance and can lead to expensive and time consuming overhaul and repair. A test rig was designed and constructed for the Allison 250-C20B combustion chamber to investigate the effects of inlet air distortion on the combustion chamber's exit temperature fields. The rig made use of the engine's diffuser tubes, combustion case, combustion liner, and first stage nozzle guide vane shield. Rig operating conditions simulated engine cruise conditions, matching the quasi-non-dimensional Mach number, equivalence ratio and Sauter mean diameter. The combustion chamber was tested with an even distribution of inlet air and a 4% difference in airflow at either side. An even distribution of inlet air to the combustion chamber did not create a uniform temperature profile and varying the inlet distribution of air exacerbated the profile's non-uniformity. The design of the combustion liner promoted the formation of an oval-shaped toroidal vortex inside the chamber, creating localized hot and cool sections separated by 90° that appeared in the exhaust. Uneven inlet air distributions skewed the oval vortex, increasing the temperature of the hot section nearest the side with the most mass flow rate and decreasing the temperature of the hot section on the opposite side. Keywords: Allison 250, Combustion, Dual-Entry, Exit Temperature Profile, Gas Turbine, Pattern Factor, Reverse Flow.

  6. A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit.

    PubMed

    Cundell, Michael J; Hutter, Lukas H; Nunes Bastos, Ricardo; Poser, Elena; Holder, James; Mohammed, Shabaz; Novak, Bela; Barr, Francis A

    2016-08-29

    PP2A-B55 is one of the major phosphatases regulating cell division. Despite its importance for temporal control during mitotic exit, how B55 substrates are recognized and differentially dephosphorylated is unclear. Using phosphoproteomics combined with kinetic modeling to extract B55-dependent rate constants, we have systematically identified B55 substrates and assigned their temporal order in mitotic exit. These substrates share a bipartite polybasic recognition determinant (BPR) flanking a Cdk1 phosphorylation site. Experiments and modeling show that dephosphorylation rate is encoded into B55 substrates, including its inhibitor ENSA, by cooperative action of basic residues within the BPR. A complementary acidic surface on B55 decodes this signal, supporting a cooperative electrostatic mechanism for substrate selection. A further level of specificity is encoded into B55 substrates because B55 displays selectivity for phosphothreonine. These simple biochemical properties, combined with feedback control of B55 activity by the phosphoserine-containing substrate/inhibitor ENSA, can help explain the temporal sequence of events during exit from mitosis. PMID:27551054

  7. Mutual regulation of cyclin-dependent kinase and the mitotic exit network

    PubMed Central

    König, Cornelia; Maekawa, Hiromi

    2010-01-01

    The mitotic exit network (MEN) is a spindle pole body (SPB)–associated, GTPase-driven signaling cascade that controls mitotic exit. The inhibitory Bfa1–Bub2 GTPase-activating protein (GAP) only associates with the daughter SPB (dSPB), raising the question as to how the MEN is regulated on the mother SPB (mSPB). Here, we show mutual regulation of cyclin-dependent kinase 1 (Cdk1) and the MEN. In early anaphase Cdk1 becomes recruited to the mSPB depending on the activity of the MEN kinase Cdc15. Conversely, Cdk1 negatively regulates binding of Cdc15 to the mSPB. In addition, Cdk1 phosphorylates the Mob1 protein to inhibit the activity of Dbf2–Mob1 kinase that regulates Cdc14 phosphatase. Our data revise the understanding of the spatial regulation of the MEN. Although MEN activity in the daughter cells is controlled by Bfa1–Bub2, Cdk1 inhibits MEN activity at the mSPB. Consistent with this model, only triple mutants that lack BUB2 and the Cdk1 phosphorylation sites in Mob1 and Cdc15 show mitotic exit defects. PMID:20123997

  8. Chk2 prevents mitotic exit when the majority of kinetochores are unattached.

    PubMed

    Petsalaki, Eleni; Zachos, George

    2014-05-12

    The spindle checkpoint delays exit from mitosis in cells with spindle defects. In this paper, we show that Chk2 is required to delay anaphase onset when microtubules are completely depolymerized but not in the presence of relatively few unattached kinetochores. Mitotic exit in Chk2-deficient cells correlates with reduced levels of Mps1 protein and increased Cdk1-tyrosine 15 inhibitory phosphorylation. Chk2 localizes to kinetochores and is also required for Aurora B-serine 331 phosphorylation in nocodazole or unperturbed early prometaphase. Serine 331 phosphorylation contributed to prometaphase accumulation in nocodazole after partial Mps1 inhibition and was required for spindle checkpoint establishment at the beginning of mitosis. In addition, expression of a phosphomimetic S331E mutant Aurora B rescued chromosome alignment or segregation in Chk2-deficient cells. We propose that Chk2 stabilizes Mps1 and phosphorylates Aurora B-serine 331 to prevent mitotic exit when most kinetochores are unattached. These results highlight mechanisms of an essential function of Chk2 in mitosis.

  9. Pitx2 expression promotes p21 expression and cell cycle exit in neural stem cells.

    PubMed

    Heldring, Nina; Joseph, Bertrand; Hermanson, Ola; Kioussi, Chrissa

    2012-11-01

    Cortical development is a complex process that involves many events including proliferation, cell cycle exit and differentiation that need to be appropriately synchronized. Neural stem cells (NSCs) isolated from embryonic cortex are characterized by their ability of self-renewal under continued maintenance of multipotency. Cell cycle progression and arrest during development is regulated by numerous factors, including cyclins, cyclin dependent kinases and their inhibitors. In this study, we exogenously expressed the homeodomain transcription factor Pitx2, usually expressed in postmitotic progenitors and neurons of the embryonic cortex, in NSCs with low expression of endogenous Pitx2. We found that Pitx2 expression induced a rapid decrease in proliferation associated with an accumulation of NSCs in G1 phase. A search for potential cell cycle inhibitors responsible for such cell cycle exit of NSCs revealed that Pitx2 expression caused a rapid and dramatic (≉20-fold) increase in expression of the cell cycle inhibitor p21 (WAF1/Cip1). In addition, Pitx2 bound directly to the p21 promoter as assessed by chromatin immunoprecipitation (ChIP) in NSCs. Surprisingly, Pitx2 expression was not associated with an increase in differentiation markers, but instead the expression of nestin, associated with undifferentiated NSCs, was maintained. Our results suggest that Pitx2 promotes p21 expression and induces cell cycle exit in neural progenitors.

  10. Airport exit and entry screening for Ebola--August-November 10, 2014.

    PubMed

    Brown, Clive M; Aranas, Aaron E; Benenson, Gabrielle A; Brunette, Gary; Cetron, Marty; Chen, Tai-Ho; Cohen, Nicole J; Diaz, Pam; Haber, Yonat; Hale, Christa R; Holton, Kelly; Kohl, Katrin; Le, Amanda W; Palumbo, Gabriel J; Pearson, Kate; Phares, Christina R; Alvarado-Ramy, Francisco; Roohi, Shah; Rotz, Lisa D; Tappero, Jordan; Washburn, Faith M; Watkins, James; Pesik, Nicki

    2014-12-12

    In response to the largest recognized Ebola virus disease epidemic now occurring in West Africa, the governments of affected countries, CDC, the World Health Organization (WHO), and other international organizations have collaborated to implement strategies to control spread of the virus. One strategy recommended by WHO calls for countries with Ebola transmission to screen all persons exiting the country for "unexplained febrile illness consistent with potential Ebola infection." Exit screening at points of departure is intended to reduce the likelihood of international spread of the virus. To initiate this strategy, CDC, WHO, and other global partners were invited by the ministries of health of Guinea, Liberia, and Sierra Leone to assist them in developing and implementing exit screening procedures. Since the program began in August 2014, an estimated 80,000 travelers, of whom approximately 12,000 were en route to the United States, have departed by air from the three countries with Ebola transmission. Procedures were implemented to deny boarding to ill travelers and persons who reported a high risk for exposure to Ebola; no international air traveler from these countries has been reported as symptomatic with Ebola during travel since these procedures were implemented.

  11. Greatwall dephosphorylation and inactivation upon mitotic exit is triggered by PP1.

    PubMed

    Ma, Sheng; Vigneron, Suzanne; Robert, Perle; Strub, Jean Marc; Cianferani, Sara; Castro, Anna; Lorca, Thierry

    2016-04-01

    Entry into mitosis is induced by the activation of cyclin-B-Cdk1 and Greatwall (Gwl; also known as MASTL in mammals) kinases. Cyclin-B-Cdk1 phosphorylates mitotic substrates, whereas Gwl activation promotes the phosphorylation of the small proteins Arpp19 and ENSA. Phosphorylated Arpp19 and/or ENSA bind to and inhibit PP2A comprising the B55 subunit (PP2A-B55; B55 is also known as PPP2R2A), the phosphatase responsible for cyclin-B-Cdk1 substrate dephosphorylation, allowing the stable phosphorylation of mitotic proteins. Upon mitotic exit, cyclin-B-Cdk1 and Gwl kinases are inactivated, and mitotic substrates are dephosphorylated. Here, we have identified protein phosphatase-1 (PP1) as the phosphatase involved in the dephosphorylation of the activating site (Ser875) of Gwl. Depletion of PP1 from meioticXenopusegg extracts maintains phosphorylation of Ser875, as well as the full activity of this kinase, resulting in a block of meiotic and mitotic exit. By contrast, preventing the reactivation of PP2A-B55 through the addition of a hyperactive Gwl mutant (GwlK72M) mainly affected Gwl dephosphorylation on Thr194, resulting in partial inactivation of Gwl and in the incomplete exit from mitosis or meiosis. We also show that when PP2A-B55 is fully reactivated by depleting Arpp19, this protein phosphatase is able to dephosphorylate both activating sites, even in the absence of PP1.

  12. Timely Endocytosis of Cytokinetic Enzymes Prevents Premature Spindle Breakage during Mitotic Exit

    PubMed Central

    Onishi, Masayuki; Yeong, Foong May

    2016-01-01

    Cytokinesis requires the spatio-temporal coordination of membrane deposition and primary septum (PS) formation at the division site to drive acto-myosin ring (AMR) constriction. It has been demonstrated that AMR constriction invariably occurs only after the mitotic spindle disassembly. It has also been established that Chitin Synthase II (Chs2p) neck localization precedes mitotic spindle disassembly during mitotic exit. As AMR constriction depends upon PS formation, the question arises as to how chitin deposition is regulated so as to prevent premature AMR constriction and mitotic spindle breakage. In this study, we propose that cells regulate the coordination between spindle disassembly and AMR constriction via timely endocytosis of cytokinetic enzymes, Chs2p, Chs3p, and Fks1p. Inhibition of endocytosis leads to over accumulation of cytokinetic enzymes during mitotic exit, which accelerates the constriction of the AMR, and causes spindle breakage that eventually could contribute to monopolar spindle formation in the subsequent round of cell division. Intriguingly, the mitotic spindle breakage observed in endocytosis mutants can be rescued either by deleting or inhibiting the activities of, CHS2, CHS3 and FKS1, which are involved in septum formation. The findings from our study highlight the importance of timely endocytosis of cytokinetic enzymes at the division site in safeguarding mitotic spindle integrity during mitotic exit. PMID:27447488

  13. Modeling Film-Coolant Flow Characteristics at the Exit of Shower-Head Holes

    NASA Technical Reports Server (NTRS)

    Garg, Vijay K.; Gaugler, R. E. (Technical Monitor)

    2000-01-01

    The coolant flow characteristics at the hole exits of a film-cooled blade are derived from an earlier analysis where the hole pipes and coolant plenum were also discretized. The blade chosen is the VKI rotor with three staggered rows of shower-head holes. The present analysis applies these flow characteristics at the shower-head hole exits. A multi-block three-dimensional Navier-Stokes code with Wilcox's k-omega model is used to compute the heat transfer coefficient on the film-cooled turbine blade. A reasonably good comparison with the experimental data as well as with the more complete earlier analysis where the hole pipes and coolant plenum were also gridded is obtained. If the 1/7th power law is assumed for the coolant flow characteristics at the hole exits, considerable differences in the heat transfer coefficient on the blade surface, specially in the leading-edge region, are observed even though the span-averaged values of h (heat transfer coefficient based on T(sub o)-T(sub w)) match well with the experimental data. This calls for span-resolved experimental data near film-cooling holes on a blade for better validation of the code.

  14. Dynamics of an SIQS epidemic model with transport-related infection and exit-entry screenings.

    PubMed

    Liu, Xianning; Chen, Xiaoping; Takeuchi, Yasuhiro

    2011-09-21

    Population dispersal, as a common phenomenon in human society, may cause the spreading of many diseases such as influenza, SARS, etc. which are easily transmitted from one region to other regions. Exit and entry screenings at the border are considered as effective ways for controlling the spread of disease. In this paper, the dynamics of an SIQS model are analyzed and the combined effects of transport-related infection enhancing and exit-entry screenings suppressing on disease spread are discussed. The basic reproduction number is computed and proved to be a threshold for disease control. If it is not greater than the unity, the disease free equilibrium is globally asymptotically stable. And there exists an endemic equilibrium which is locally asymptotically stable if the reproduction number is greater than unity. It is shown that the disease is endemic in the sense of permanence if and only if the endemic equilibrium exists. Exit screening and entry screening are shown to be helpful for disease eradication since they can always have the possibility to eradicate the disease endemic led by transport-related infection and furthermore have the possibility to eradicate disease even when the isolated cites are disease endemic. PMID:21740917

  15. Exit competencies in pathology and laboratory medicine for graduating medical students: the Canadian approach.

    PubMed

    Ford, Jason; Pambrun, Chantale

    2015-05-01

    Physicians in every medical and surgical field must be able to use pathology concepts and skills in their practice: for example, they must order and interpret the correct laboratory tests, they must use their understanding of pathogenesis to diagnose and treat, and they must work with the laboratory to care for their patients. These important concepts and skills may be ignored by medical schools and even national/international organizations setting graduation expectations for medical students. There is an evolving international consensus about the importance of exit competencies for medical school graduates, which define the measurable or observable behaviors each graduate must be able to demonstrate. The Canadian Association of Pathologists (CAP) Education Group set out to establish the basic competencies in pathology and laboratory medicine which should be expected of every medical graduate: not competencies for pathologists, but for medical graduates who intend to enter any residency program. We defined 4 targets for pathology and laboratory medicine exit competencies: that they represent only measurable behaviors, that they be clinically focused, that they be generalizable to every medical graduate, and that the final competency document be user-friendly. A set of competencies was developed iteratively and underwent final revision at the 2012 CAP annual meeting. These competencies were subsequently endorsed by the CAP executive and the Canadian Leadership Council on Laboratory Medicine. This clinically focused consensus document provides the first comprehensive list of exit competencies in pathology and laboratory medicine for undergraduate medical education.

  16. A Reconfigurable Functional Unit with Conditional Execution for Multi-Exit Custom Instructions

    NASA Astrophysics Data System (ADS)

    Noori, Hamid; Mehdipour, Farhad; Inoue, Koji; Murakami, Kazuaki

    Encapsulating critical computation subgraphs as application-specific instruction set extensions is an effective technique to enhance the performance of embedded processors. However, the addition of custom functional units to the base processor is required to support the execution of these custom instructions. Although automated tools have been developed to reduce the long design time needed to produce a new extensible processor for each application, short time-to-market, significant non-recurring engineering and design costs are issues. To address these concerns, we introduce an adaptive extensible processor in which custom instructions are generated and added after chip-fabrication. To support this feature, custom functional units (CFUs) are replaced by a reconfigurable functional unit (RFU). The proposed RFU is based on a matrix of functional units which is multi-cycle with the capability of conditional execution. A quantitative approach is utilized to propose an efficient architecture for the RFU and fix its constraints. To generate more effective custom instructions, they are extended over basic blocks and hence, multiple exits custom instructions are proposed. Conditional execution has been added to the RFU to support the multi-exit feature of custom instructions. Experimental results show that multi-exit custom instructions enhance the performance by an average of 67% compared to custom instructions limited to one basic block. A maximum speedup of 4.7, compared to a general embedded processor, and an average speedup of 1.85 was achieved on MiBench benchmark suite.

  17. A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit.

    PubMed

    Cundell, Michael J; Hutter, Lukas H; Nunes Bastos, Ricardo; Poser, Elena; Holder, James; Mohammed, Shabaz; Novak, Bela; Barr, Francis A

    2016-08-29

    PP2A-B55 is one of the major phosphatases regulating cell division. Despite its importance for temporal control during mitotic exit, how B55 substrates are recognized and differentially dephosphorylated is unclear. Using phosphoproteomics combined with kinetic modeling to extract B55-dependent rate constants, we have systematically identified B55 substrates and assigned their temporal order in mitotic exit. These substrates share a bipartite polybasic recognition determinant (BPR) flanking a Cdk1 phosphorylation site. Experiments and modeling show that dephosphorylation rate is encoded into B55 substrates, including its inhibitor ENSA, by cooperative action of basic residues within the BPR. A complementary acidic surface on B55 decodes this signal, supporting a cooperative electrostatic mechanism for substrate selection. A further level of specificity is encoded into B55 substrates because B55 displays selectivity for phosphothreonine. These simple biochemical properties, combined with feedback control of B55 activity by the phosphoserine-containing substrate/inhibitor ENSA, can help explain the temporal sequence of events during exit from mitosis.

  18. Modeling of plasma processes in the slowly diverging magnetic fields at the exit of an applied-field magnetoplasmadynamic thruster

    SciTech Connect

    Li, Min; Tang, Hai-Bin; Ren, Jun-Xue; York, Thomas M.

    2013-10-15

    The performance of plasma thrusters with applied electric and magnetic fields can be enhanced by increasing the magnetic field strength, which is applied in the thrust chamber and the exit region propulsive plume. The ejected plasma which passes through a slowly diverging magnetic field will expand but can be restricted within the magnetic nozzle fields. To examine in detail the processes that occur, a new method with Particle-in-cell calculations is applied here. A two-dimensional axisymmetric particle dynamic code is used to model an AF-MPDT (Applied-field Magnetoplasmadynamic Thruster) for which extensive experimental data are available; it used Ar propellant and had applied magnetic coils of 101.5 mm radius and 153 mm length. From the results of the simulation study, it is found that total thrust increases linearly with magnetic field strength in the range of 0–0.1 T, but it decreases with increasing applied magnetic field up to 0.6 T. Thrust efficiency is found to increase to a maximum of 8.4% when B = 0.1 T; further, the peak value of nozzle efficiency reaches 91% at a moderate magnetic field (0.3 T). In detail, it is found that distributions of plasma density (10{sup 14}–10{sup 15} m{sup −3}) that form in the magnetic nozzle demonstrate a significant pattern of concentration up to fields of B = 0.3 T where ions begin to be magnetized. However, azimuthal velocities of ions behave differently with different degrees of magnetization, i.e., weakly magnetized ions follow rotating electrons in a right-handed direction, while fully magnetized ions revolve in left-handed direction due to electromagnetic forces. Notably, a feedback effect on total magnetic field due to plasma motion identified in other studies is not found to be present in the working conditions of the AF-MPDT examined here.

  19. Self-Actualization Effects Of A Marathon Growth Group

    ERIC Educational Resources Information Center

    Jones, Dorothy S.; Medvene, Arnold M.

    1975-01-01

    This study examined the effects of a marathon group experience on university student's level of self-actualization two days and six weeks after the experience. Gains in self-actualization as a result of marathon group participation depended upon an individual's level of ego strength upon entering the group. (Author)

  20. The Self-Actualization of Polk Community College Students.

    ERIC Educational Resources Information Center

    Pearsall, Howard E.; Thompson, Paul V., Jr.

    This article investigates the concept of self-actualization introduced by Abraham Maslow (1954). A summary of Maslow's Needs Hierarchy, along with a description of the characteristics of the self-actualized person, is presented. An analysis of humanistic education reveals it has much to offer as a means of promoting the principles of…