Bartonella Endocarditis and Pauci-Immune Glomerulonephritis

PubMed Central

Raybould, Jillian E.; Raybould, Alison L.; Morales, Megan K.; Zaheer, Misbah; Lipkowitz, Michael S.; Timpone, Joseph G.; Kumar, Princy N.

2016-01-01

Abstract Among culture-negative endocarditis in the United States, Bartonella species are the most common cause, with Bartonella henselae and Bartonella quintana comprising the majority of cases. Kidney manifestations, particularly glomerulonephritis, are common sequelae of infectious endocarditis, with nearly half of all Bartonella patients demonstrating renal involvement. Although a pauci-immune pattern is a frequent finding in infectious endocarditis–associated glomerulonephritis, it is rarely reported in Bartonella endocarditis. Anti–neutrophil cytoplasmic antibody (ANCA) positivity can be seen with many pathogens causing endocarditis and has been previously reported with Bartonella species. In addition, ANCA-associated vasculitis can also present with renal and cardiac involvement, including noninfectious valvular vegetations and pauci-immune glomerulonephritis. Given the overlap in their clinical presentation, it is difficult to differentiate between Bartonella endocarditis and ANCA-associated vasculitis but imperative to do so to guide management decisions. We present a case of ANCA-positive Bartonella endocarditis with associated pauci-immune glomerulonephritis that was successfully treated with medical management alone. PMID:27885316

Immunofluorescent localization of Staphylococcos aureus antigen in acute bacterial endocarditis nephritis.

PubMed

Yum, M; Wheat, L J; Maxwell, D; Edwards, J L

1978-11-01

A 75-year-old man with Staphylococcus aureus endocarditis in whom acute diffuse proliferative glomerulonephritis developed is described. The light- and electron-microscopic changes of the glomeruli in this case were identical to those of acute poststreptococcal glomerulonephritis. Immunofluorescence revealed deposition of immunoglobulins and complement in the glomeruli. In addition, bacterial antigenic material was demonstrated in the glomeruli by indirect immunofluorescence. These observations further support the hypothesis of an immune-complex pathogenesis in this form of glomerulonephritis.

Discovery of 21 New Changing-look AGNs: Study on Evolution of AGNs and AGN Host Galaxies

NASA Astrophysics Data System (ADS)

Yang, Qian; Wu, Xuebing; Fan, Xiaohui; Jiang, Linhua; McGreer, Ian; Shangguan, Jinyi; Yao, Su; Wang, Bingquan; Joshi, Ravi; Green, Richard F.; Wang, Feige; Feng, Xiaotong; Fu, Yuming; Yang, Jinyi; Liu, Yuanqi

2018-01-01

The rare case of changing-look (CL) AGNs, with the appearance or disappearance of broad Balmer emission lines within a few years, challenges our understanding of the AGN unified model. We present a sample of 21 new CL AGNs at 0.08 < z < 0.58. The new sample doubles the number of such objects known to date. These new CL AGNs were discovered by several ways, from repeat spectra in the SDSS, repeat spectra in the Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST) and SDSS, and from photometric variability and new spectroscopic observations. The estimated upper limits of transition timescale of the CL AGNs in this sample span from 0.9 to 13 years in rest-frame. The continuum flux in the optical and mid-infrared becomes brighter when the CL AGNs turn on, or vice versa. Variations of more than 0.2 mag in the mid-infrared W1 band, from the Wide-field Infrared Survey Explorer (WISE), were detected in 15 CL AGNs during the transition. The optical and mid-infrared variability is not consistent with the scenario of variable obscuration in 10 CL AGNs at higher than 3σ confidence level. We confirm a bluer-when-brighter trend in the optical. However, the mid-infrared colors W1‑W2 become redder when the objects become brighter in the W1 band, possibly due to a stronger hot dust contribution in the W2 band when the AGN activity becomes stronger. The physical mechanism of type transition is important for understanding the evolution of AGNs. The rare CL AGNs provide exceptional cases for the black hole and host stellar velocity dispersion relation studies at higher redshift. The faint state spectrum can be used to obtain the host stellar velocity dispersion without contamination from AGN component, and the bright state spectrum can be used to calculate the black hole mass with broad Balmer emission lines. The images at the non-AGN phase of CL AGNs are useful for studies of AGN host galaxies avoiding contamination from the luminous central engines.

Membranoproliferative Glomerulonephritis and Persistent Hypocomplementaemia

PubMed Central

Cameron, J. S.; Glasgow, E. F.; Ogg, C. S.; White, R. H. R.

1970-01-01

The clinical, laboratory, and histological findings of 50 patients with membranoproliferative glomerulonephritis are described. Three-quarters of the patients, who were mostly older children and young adults, presented clinically with a mixture of “nephritic” and “nephrotic” symptoms; the remaining quarter had no symptoms and were diagnosed after the discovery of proteinuria and microscopic haematuria. Though this clinical picture may occur in other forms of glomerulonephritis, the patients described here were unified as a group by their glomerular morphological appearance—namely, a combination of mesangial proliferation and capillary wall thickening, mainly due to subendothelial accumulations of mesangial matrix. In 68% serum C3 (β10-globulin) levels were reduced initially, while a further 16% subsequently showed a fall to abnormally low levels. All patients had substantial proteinuria, usually of moderately impaired selectivity, and all but one had haematuria in addition. Children frequently presented with an illness resembling acute nephritis, whereas adults usually had a nephrotic syndrome from the start. In 31 patients, followed for periods of one to eight and a half years, serial measurements of glomerular filtration rate were made. Sixteen have experienced no deterioration of renal function, though their proteinuria continues unchanged. Fifteen have shown progressive deterioration; six of them are still well, six are on regular dialysis treatment, and three have died. Treatment with corticosteroids, azathioprine, or cyclophosphamide, alone or in combination, did not seem to influence the course of the disease, and another two patients died from complications of steroid therapy. The disease usually runs a chronic course and appears to be progressive. ImagesFig. 1Fig. 2Fig. 3Fig. 4Fig. 5Fig. 6 PMID:4097129

Starburst or AGN dominance in submm-luminous candidate AGN

NASA Astrophysics Data System (ADS)

Coppin, Kristen; Alexander, Dave; Aretxaga, Itziar; Blain, Andrew; Chapman, Scott; Clements, Dave; Dunlop, James; Dunne, Loretta; Dye, Simon; Farrah, Duncan; Hughes, David; Ivison, Rob; Kim, Sungeun; Menendez-Delmestre, Karin; Oliver, Sebastian; Page, Mat; Pope, Alexandra; Rowan-Robinson, Michael; Scott, Douglas; Smail, Ian; Swinbank, Mark; Vaccari, Mattia; van Kampen, Eelco

2008-03-01

It is widely believed that starbursts/ULIRGs and AGN activity are triggered by galaxy interactions and merging; and sub-mm selected galaxies (SMGs) seem to be simply high redshift ULIRGs, observed near the peak of activity. In this evolutionary picture every SMG would host an AGN, which would eventually grow a black hole strong enough to blow off all of the gas and dust leaving an optically luminous QSO. In order to probe this evolutionary sequence, a crucial sub-sample to focus on would be the 'missing link' sources, which demonstrate both strong starburst and AGN signatures and to determine if the starburst is the main power source even in SMGs when we have evidence that an AGN is present. The best way to determine if a dominant AGN is present is to look in the mid-IR for their signatures, since often even deep X-ray observations miss identifying the presence of AGN in heavily dust-obscured SMGs. We have selected a sample of SMGs which are good candidates for harboring powerful AGN on the basis of their IRAC colours (S8um/S4.5um>2). Once we confirm these SMGs are AGN-dominated, we can then perform an audit of the energy balance between star-formation and AGN within this special sub-population of SMGs where the BH has grown appreciably to begin heating the dust emission. The proposed observations with IRS will probe the physics of how SMGs evolve from a cold-dust starburst-dominated ULIRG to an AGN/QSO by measuring the level of the mid-IR continuum, PAH luminosity, and Si absorption in these intermediate `transitory' AGN/SMGs.

Membranous glomerulonephritis associated with enterococcal endocarditis.

PubMed

Iida, H; Mizumura, Y; Uraoka, T; Takata, M; Sugimoto, T; Miwa, A; Yamagishi, T

1985-01-01

An autopsy case of membranous glomerulonephritis associated with enterococcal endocarditis was reported. Although enterococcal antigen was not identified in glomerular deposits, the eluate from the patient's renal tissue was shown to specifically recombine with cells of the enterococcus isolated from his own ante mortem blood. Hypocomplementemia, circulating immune complexes and antienterococcal antibodies were also observed. These findings suggest that enterococcus-related immune complexes played a role in the pathogenesis of glomerulonephritis associated with enterococcal endocarditis in this patient.

Successful treatment of post-MRSA infection glomerulonephritis with steroid therapy.

PubMed

Okuyama, S; Wakui, H; Maki, N; Kuroki, J; Nishinari, T; Asakura, K; Komatsuda, A; Sawada, K

2008-10-01

A 48-year-old man without underlying disease developed mediastinitis and was treated by mediastinal drainage. Methicillin-resistant Staphylococcus aureus (MRSA) was detected in a culture of the abscess material. He was treated with anti-MRSA antibiotics and the MRSA infection improved. Four weeks after the onset of MRSA infection, he developed rapidly progressive glomerulonephritis (RPGN) with nephrotic syndrome (NS). A renal biopsy showed endocapillary proliferative glomerulonephritis with IgA-predominant glomerular deposition. These clinicopathological findings were consistent with those in glomerulonephritis following MRSA infection (post-MRSA infection glomerulonephritis). The level of serum creatinine increased to 6.3 mg/dl, 7 weeks after the onset of RPGN. At that time, the eradication of MRSA infection was considered. He was given middle-dose steroid therapy. Thereafter, his RPGN with NS improved. MRSA infection did not recur. If the disease activity of post-MRSA infection glomerulonephritis persists after the disappearance of MRSA infection, the application of immunosuppressive therapy with steroids may be useful.

AGN feedback in action? - outflows and star formation in type 2 AGNs

NASA Astrophysics Data System (ADS)

Woo, Jong-Hak

2017-01-01

We present the statistical constraints on the ionized gas outflows and their connection to star formation, using a large sample of ~110,000 AGNs and star-forming galaxies at z < 0.3. First, we find a dramatic difference of the outflow signatures between AGNs and star-forming galaxies based on the [OIII] emission line kinematics. While the [OIII] velocity and velocity dispersion of star forming galaxies can be entirely accounted by the gravitational potential of host galaxies, AGNs clearly show non-gravitational kinematics, which is comparable to or stronger than the virial motion caused by the gravitational potential. Second, the distribution in the [OIII] velocity - velocity dispersion diagram dramatically expands toward large values with increasing AGN luminosity, implying that the outflows are AGN-driven. Third, the fraction of AGNs with a signature of outflow kinematics, steeply increases with AGN luminosity and Eddington ratio. In particular, the majority of luminous AGNs presents strong non-gravitational kinematics in the [OIII] profile. Interestingly, we find that the specific star formation of non-outflow AGNs is much lower than that of strong outflow AGNs, while the star formation rate of strong outflow AGNs is comparable to that of star forming galaxies. We interpret this trend as a delayed AGN feedback as it takes dynamical time for the outflows to suppress star formation in galactic scales.

Starburst or AGN Dominance in Submillimetre-Luminous Candidate AGN?

NASA Astrophysics Data System (ADS)

Coppin, Kristen; Pope, Alexandra; Menéndez-Delmestre, Karín; Alexander, David M.; Dunlop, James

2010-06-01

It is widely believed that ultraluminous infrared (IR) galaxies and active galactic nuclei (AGN) activity are triggered by galaxy interactions and merging, with the peak of activity occurring at z~2, where submillimetre galaxies are thousands of times more numerous than local ULIRGs. In this evolutionary picture, submillimetre galaxies (SMGs) would host an AGN, which would eventually grow a black hole (BH) strong enough to blow off all of the gas and dust leaving an optically luminous QSO. To probe this evolutionary sequence we have focussed on the `missing link' sources, which demonstrate both strong starburst (SB) and AGN signatures, in order to determine if the SB is the main power source even in SMGs when we have evidence that an AGN is present from their IRAC colours. The best way to determine if a dominant AGN is present is to look for their signatures in the mid-infrared with the Spitzer IRS, since often even deep X-ray observations miss identifying the presence of AGN in heavily dust-obscured SMGs. We present the results of our audit of the energy balance between star-formation and AGN within this special sub-population of SMGs-where the BH has grown appreciably to begin heating the dust emission.

Eculizumab for dense deposit disease and C3 glomerulonephritis.

PubMed

Bomback, Andrew S; Smith, Richard J; Barile, Gaetano R; Zhang, Yuzhou; Heher, Eliot C; Herlitz, Leal; Stokes, M Barry; Markowitz, Glen S; D'Agati, Vivette D; Canetta, Pietro A; Radhakrishnan, Jai; Appel, Gerald B

2012-05-01

The principle defect in dense deposit disease and C3 glomerulonephritis is hyperactivity of the alternative complement pathway. Eculizumab, a monoclonal antibody that binds to C5 to prevent formation of the membrane attack complex, may prove beneficial. In this open-label, proof of concept efficacy and safety study, six subjects with dense deposit disease or C3 glomerulonephritis were treated with eculizumab every other week for 1 year. All had proteinuria >1 g/d and/or AKI at enrollment. Subjects underwent biopsy before enrollment and repeat biopsy at the 1-year mark. The subjects included three patients with dense deposit disease (including one patient with recurrent dense deposit disease in allograft) and three patients with C3 glomerulonephritis (including two patients with recurrent C3 glomerulonephritis in allograft). Genetic and complement function testing revealed a mutation in CFH and MCP in one subject each, C3 nephritic factor in three subjects, and elevated levels of serum membrane attack complex in three subjects. After 12 months, two subjects showed significantly reduced serum creatinine, one subject achieved marked reduction in proteinuria, and one subject had stable laboratory parameters but histopathologic improvements. Elevated serum membrane attack complex levels normalized on therapy and paralleled improvements in creatinine and proteinuria. Clinical and histopathologic data suggest a response to eculizumab in some but not all subjects with dense deposit disease and C3 glomerulonephritis. Elevation of serum membrane attack complex before treatment may predict response. Additional research is needed to define the subgroup of dense deposit disease/C3 glomerulonephritis patients in whom eculizumab therapy can be considered.

Identifying Distant AGNs

NASA Astrophysics Data System (ADS)

Trouille, Laura; Barger, Amy; Tremonti, Christy

2014-07-01

The Baldwin, Phillips, and Terlevich emission-line ratio diagnostic ([OIII]/Hβ versus [NII]/Hα, hereafter BPT diagram) efficiently separates galaxies whose signal is dominated by star formation (BPT-SF) from those dominated by AGN activity (BPT-AGN). Yet the BPT diagram is limited to z<0.5, the redshift at which [NII]λ6584 leaves the optical spectral window. Using the Sloan Digital Sky Survey (SDSS), we construct a new diagnostic, or TBT diagram, that is based on rest-frame g-z color, [NeIII]λ3869, and [OII]λλ3726+3729 and can be used for galaxies out to z<1.4. The TBT diagram identifies 98.7% of the SDSS BPT-AGN as TBT-AGN and 97% of the SDSS BPT-SF as TBT-SF. Furthermore, it identifies 97% of the OPTX Chandra X-ray selected AGNs as TBT-AGN. This is in contrast to the BPT diagram, which misidentifies 20% of X-ray selected AGNs as BPT-SF.

Eculizumab for Dense Deposit Disease and C3 Glomerulonephritis

PubMed Central

Smith, Richard J.; Barile, Gaetano R.; Zhang, Yuzhou; Heher, Eliot C.; Herlitz, Leal; Stokes, M. Barry; Markowitz, Glen S.; D’Agati, Vivette D.; Canetta, Pietro A.; Radhakrishnan, Jai; Appel, Gerald B.

2012-01-01

Summary Background and objectives The principle defect in dense deposit disease and C3 glomerulonephritis is hyperactivity of the alternative complement pathway. Eculizumab, a monoclonal antibody that binds to C5 to prevent formation of the membrane attack complex, may prove beneficial. Design, setting, participants, & measurements In this open-label, proof of concept efficacy and safety study, six subjects with dense deposit disease or C3 glomerulonephritis were treated with eculizumab every other week for 1 year. All had proteinuria >1 g/d and/or AKI at enrollment. Subjects underwent biopsy before enrollment and repeat biopsy at the 1-year mark. Results The subjects included three patients with dense deposit disease (including one patient with recurrent dense deposit disease in allograft) and three patients with C3 glomerulonephritis (including two patients with recurrent C3 glomerulonephritis in allograft). Genetic and complement function testing revealed a mutation in CFH and MCP in one subject each, C3 nephritic factor in three subjects, and elevated levels of serum membrane attack complex in three subjects. After 12 months, two subjects showed significantly reduced serum creatinine, one subject achieved marked reduction in proteinuria, and one subject had stable laboratory parameters but histopathologic improvements. Elevated serum membrane attack complex levels normalized on therapy and paralleled improvements in creatinine and proteinuria. Conclusions Clinical and histopathologic data suggest a response to eculizumab in some but not all subjects with dense deposit disease and C3 glomerulonephritis. Elevation of serum membrane attack complex before treatment may predict response. Additional research is needed to define the subgroup of dense deposit disease/C3 glomerulonephritis patients in whom eculizumab therapy can be considered. PMID:22403278

Current pharmacotherapy for the treatment of crescentic glomerulonephritis.

PubMed

Tam, Frederick W K

2006-11-01

Glomerulonephritis is an important cause of end-stage renal disease. Crescentic glomerulonephritis is the most severe form of glomerulonephritis and, if untreated, patients will develop renal failure within days or weeks of diagnosis. Current immunotherapy consists of corticosteroids, cytotoxic drugs and plasma exchange. Challenges include minimising toxicity of therapy, preventing relapse in antineutrophil cytoplasmic antibodies-associated vasculitis and finding an effective treatment for crescentic IgA nephropathy. There are opportunities for more specific therapies using monoclonal antibodies to T cells (and their co-stimulatory receptors), B cells and cytokines, or pharmacological inhibitors of signal transduction. Their efficacy and safety remain to be established with controlled clinical trials. Recent development of urinary cytokine measurement provides a noninvasive biomarker of renal disease activity, which is useful in monitoring response to therapy and assessing prognosis.

Probing AGN Accretion Physics through AGN Variability: Insights from Kepler

NASA Astrophysics Data System (ADS)

Kasliwal, Vishal Pramod

Active Galactic Nuclei (AGN) exhibit large luminosity variations over the entire electromagnetic spectrum on timescales ranging from hours to years. The variations in luminosity are devoid of any periodic character and appear stochastic. While complex correlations exist between the variability observed in different parts of the electromagnetic spectrum, no frequency band appears to be completely dominant, suggesting that the physical processes producing the variability are exceedingly rich and complex. In the absence of a clear theoretical explanation of the variability, phenomenological models are used to study AGN variability. The stochastic behavior of AGN variability makes formulating such models difficult and connecting them to the underlying physics exceedingly hard. We study AGN light curves serendipitously observed by the NASA Kepler planet-finding mission. Compared to previous ground-based observations, Kepler offers higher precision and a smaller sampling interval resulting in potentially higher quality light curves. Using structure functions, we demonstrate that (1) the simplest statistical model of AGN variability, the damped random walk (DRW), is insufficient to characterize the observed behavior of AGN light curves; and (2) variability begins to occur in AGN on time-scales as short as hours. Of the 20 light curves studied by us, only 3-8 may be consistent with the DRW. The structure functions of the AGN in our sample exhibit complex behavior with pronounced dips on time-scales of 10-100 d suggesting that AGN variability can be very complex and merits further analysis. We examine the accuracy of the Kepler pipeline-generated light curves and find that the publicly available light curves may require re-processing to reduce contamination from field sources. We show that while the re-processing changes the exact PSD power law slopes inferred by us, it is unlikely to change the conclusion of our structure function study-Kepler AGN light curves indicate

Acute toxic nephropathies: clinical pathologic correlations.

PubMed

Muehrcke, R C; Volini, F I; Morris, A M; Moles, J B; Lawrence, A G

1976-01-01

Man's ever increasing exposure to numerous drugs and chemicals, which are the results of medical and industrial progress, produces a by-product of acute toxic nephropathies. These include acute toxic renal failure, drug-induced acute oliguric renal failure, acute hemorrhagic glomerulonephritis, nephrotic syndrome, tubular disturbances and potassium deficiency. In depth information is provided for the previously mentioned disorders.

ANCA positivity in a patient with infective endocarditis-associated glomerulonephritis: a diagnostic dilemma.

PubMed

Ghosh, Gopal Chandra; Sharma, Brijesh; Katageri, Bhimarey; Bhardwaj, Minakshi

2014-09-01

Glomerulonephritis (GN) is an immunological phenomenon in bacterial endocarditis. These may be pauci-immune/vasculitic GN, post-infective GN, and sub-endothelial membranoproliferative glomerulonephritis. Each type of glomerulonephritis usually occurs in isolation. We report a case of infective endocarditis with dual existence of pauci-immune/vasculitic GN and post infective type of GN at the same time.

[Transfer of the AGnES concept to the regular German health-care system: legal evaluation, reimbursement, qualification].

PubMed

van den Berg, N; Kleinke, S; Heymann, R; Oppermann, R F; Jakobi, B; Hoffmann, W

2010-05-01

According to an amendment of German social security legislation, the AGnES concept of delegation of certain tasks of medical care, especially house calls, by general practitioners (GPs) to qualified practice employees (AGnES employees), will be transferred into the regular German health care system from January 2009 onward. The concept was developed to support GPs in regions with imminent gaps in primary care. Patient data, the specifically delegated and all other activities carried out by the AGnES employees in the AGnES projects were digitally documented. Additionally, the participating GPs, AGnES employees and patients underwent a set of standardised interviews. A curriculum to qualify the AGnES employees and to define the requirements needed was developed. A legal assessment of all delegated activities was carried out, and an economical model to calculate the necessary allowance was calculated. In seven model projects in four federal states in Germany, 11,228 house calls were carried out involving 1,424, mostly multimorbid, patients (mean age: 78.6 years). A modular structured curriculum, considering the basic education and acquired competences, was developed. It allows for an individual qualification of the AGnES employees. The result of the legal assessment was the central relevance of the qualification of the practice employees according to the AGnES curriculum as the essential condition for carrying out the entire range of activities of the AGnES concept. The economic model revealed euro 21.58 for a house call by an AGnES employee. The underlying model referred to underserved regions. A successful transfer of the AGnES concept with a high standard of quality into regular health-care depends on several factors. Of particular importance is the specific qualification of the practice employees, which is a central legal condition for the delegation of medical tasks from GPs to AGnEs employees. A second determining factor is also an adequate reimbursement within

Role of immunoflourescence in the diagnosis of glomerulonephritis.

PubMed

Nasir, Humaira; Chaudhry, Sarah; Raza, Wajiha; Moatasim, Ambreen; Mamoon, Nadira; Akhtar, Noreen

2012-03-01

To correlate the findings of immunoflorescence (IF) with morphology in renal biopsies of patients with glomerulonephritis (GN) of both primary and secondary nature. The cross-sectional analytical study was conducted at the Shifa International Hospital's Department of Pathology form March 2007 to August 2008, during which a total of 207 renal biopsies were done. Of them, the study included 92 cases which were diagnosed as primary or secondary glomerulonephritis under light microscope. Those cases were selected in which both light microscopy (LM) and immunoflorescence were done. Of the 92 patients, 79 (85.8%) were adults (> or = 19 years) and 13 (14%) were children (< 19 years). The mean age of adults was 36.44 +/- 11.55 (range 19-69 years) and that of the children was 10.54 +/- 3.85 years (range 4-18 years). immunoflorescence changed the morphologic diagnosis in 20 (21.73%) cases. The pattern of disease was: membranous glomerulonephritis in 24%, focal segmental glomerulosclerosis (FSGS) in 18.4%, mesangiocapillary glomerulonephritis in 2%, and minimal change disease (MCD) in 16% of the cases. Light microscopy alone can misdiagnose renal disease. This is especially important in cases of early stage membranous, IgA nephropathy (IgAN), Lupus nephritis and IgM nephropathy (IgMN), as these entities can only be diagnosed by correlating the microscopic, immunoflorescence findings and clinical details.

Signatures of AGN feedback

NASA Astrophysics Data System (ADS)

Wylezalek, Dominika; Zakamska, Nadia L.; MaNGA-GMOS Team

2017-01-01

Feedback from actively accreting SMBHs (Active Galactic Nuclei, AGN) is now widely considered to be the main driver in regulating the growth of massive galaxies. Observational proof for this scenario has, however, been hard to come by. Many attempts at finding a conclusive observational proof that AGN may be able to quench star formation and regulate the host galaxies' growth have shown that this problem is highly complex.I will present results from several projects that focus on understanding the power, reach and impact of feedback processes exerted by AGN. I will describe recent efforts in our group of relating feedback signatures to the specific star formation rate in their host galaxies, where our results are consistent with the AGN having a `negative' impact through feedback on the galaxies' star formation history (Wylezalek+2016a,b). Furthermore, I will show that powerful AGN-driven winds can be easily hidden and not be apparent in the integrated spectrum of the galaxy. This implies that large IFU surveys, such as the SDSS-IV MaNGA survey, might uncover many previously unknown AGN and outflows that are potentially very relevant for understanding the role of AGN in galaxy evolution (Wylezalek+2016c)!

The 60-month all-sky BAT Survey of AGN and the Anisotropy of Nearby AGN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ajello, M.; /KIPAC, Menlo Park; Alexander, D.M.

2012-04-02

Surveys above 10 keV represent one of the the best resources to provide an unbiased census of the population of Active Galactic Nuclei (AGN). We present the results of 60 months of observation of the hard X-ray sky with Swift/BAT. In this timeframe, BAT detected (in the 15-55 keV band) 720 sources in an all-sky survey of which 428 are associated with AGN, most of which are nearby. Our sample has negligible incompleteness and statistics a factor of {approx}2 larger over similarly complete sets of AGN. Our sample contains (at least) 15 bona-fide Compton-thick AGN and 3 likely candidates. Compton-thickmore » AGN represent a {approx}5% of AGN samples detected above 15 keV. We use the BAT dataset to refine the determination of the LogN-LogS of AGN which is extremely important, now that NuSTAR prepares for launch, towards assessing the AGN contribution to the cosmic X-ray background. We show that the LogN-LogS of AGN selected above 10 keV is now established to a {approx}10% precision. We derive the luminosity function of Compton-thick AGN and measure a space density of 7.9{sub -2.9}{sup +4.1} x 10{sup -5} Mpc{sup -3} for objects with a de-absorbed luminosity larger than 2 x 10{sup 42} erg s{sup -1}. As the BAT AGN are all mostly local, they allow us to investigate the spatial distribution of AGN in the nearby Universe regardless of absorption. We find concentrations of AGN that coincide spatially with the largest congregations of matter in the local ({le} 85 Mpc) Universe. There is some evidence that the fraction of Seyfert 2 objects is larger than average in the direction of these dense regions.« less

Is there a relationship between AGN and star formation in IR-bright AGNs?

NASA Astrophysics Data System (ADS)

Dai, Y. Sophia; Wilkes, Belinda J.; Bergeron, Jacqueline; Kuraszkiewicz, Joanna; Omont, Alain; Atanas, Adam; Teplitz, Harry I.

2018-05-01

We report the relationship between the luminosities of active galactic nuclei (AGNs) and the rates of star formation (SF) for a sample of 323 far-infrared (FIR)-detected AGNs. This sample has a redshift range of 0.2 AGN hosts, the total IR luminosity (8-1000 μm) has a significant AGN contribution (average˜20%), and we suggest using the FIR luminosity (30-1000 μm) as a more reliable star formation rate (SFR) estimator. We also conclude that monochromatic luminosities at 60 and 100 μ m are also good SFR indicators with negligible AGN contributions, and are less sensitive than integrated infrared luminosities to the shape of the AGN SED, which is uncertain at λ >100 μm. Significant bivariate LX-LIR correlations are found, which remain significant in the combined sample when using residual partial correlation analysis to account for the inherent redshift dependence. No redshift or mass dependence is found for the ratio between SFR and black hole accretion rate (BHAR), which has a mean and scatter of log (SFR/BHAR) =3.1 ± 0.5, agreeing with the local mass ratio between supermassive black hole and host galaxies. The large scatter in this ratio and the strong AGN-SF correlation found in these IR-bright AGNs are consistent with the scenario of an AGN-SF dependence on a common gas supply, regardless of the evolutionary model.

Low-level laser therapy improves crescentic glomerulonephritis in rats.

PubMed

Yamato, Masanori; Kaneda, Akira; Kataoka, Yosky

2013-07-01

Low-level laser therapy (LLLT) can reduce inflammation in a variety of clinical conditions, including trauma, postherpetic neuralgia, and rheumatoid arthritis. However, the effect of LLLT on internal organs has not been elucidated. The goal of the present study was to investigate the anti-inflammatory effect of daily external LLLT in an animal model of crescentic glomerulonephritis. Crescentic glomerulonephritis was induced in male Wister Kyoto rats by intravenous injection of antibody for glomerular basement membrane (GBM). The rats were irradiated with a low-reactive level diode laser with an infrared wavelength of 830 nm from the shaved skin surface once a day for 14 days (irradiation spot size on the skin surface, 2.27 cm(2); power intensity, 880 mW/cm(2); irradiation mode, continuous mode; irradiation time, 250 s; energy, 500 J; energy density, 220 J/cm(2)). After laser irradiation for 14 days, animals were killed, and the extent of inflammation was evaluated. Expression of gene for inflammatory cytokines including interleukin (IL)-1β and tumor necrosis factor alpha (TNF-α) was assessed by reverse transcription polymerase chain reaction. Crescent formation in glomeruli and infiltration of macrophages and lymphocytes were assessed by histochemical observation. Injection of anti-GBM antibody induced severe glomerulonephritis with crescent formation. Histological observations indicated that LLLT suppressed crescent formation and infiltration of ED1+ macrophages and CD8+ lymphocytes into the glomeruli. LLLT attenuated the levels of IL-1β and TNF-α messenger RNA in the renal cortex. Externally directed LLLT suppresses the activity of rat anti-GBM crescentic glomerulonephritis in rats. LLLT has the potential to be used for direct treatment of glomerulonephritis.

Targeted delivery of celastrol to mesangial cells is effective against mesangioproliferative glomerulonephritis.

PubMed

Guo, Ling; Luo, Shi; Du, Zhengwu; Zhou, Meiling; Li, Peiwen; Fu, Yao; Sun, Xun; Huang, Yuan; Zhang, Zhirong

2017-10-12

Mesangial cells-mediated glomerulonephritis is a frequent cause of end-stage renal disease. Here, we show that celastrol is effective in treating both reversible and irreversible mesangioproliferative glomerulonephritis in rat models, but find that its off-target distributions cause severe systemic toxicity. We thus target celastrol to mesangial cells using albumin nanoparticles. Celastrol-albumin nanoparticles crosses fenestrated endothelium and accumulates in mesangial cells, alleviating proteinuria, inflammation, glomerular hypercellularity, and excessive extracellular matrix deposition in rat anti-Thy1.1 nephritis models. Celastrol-albumin nanoparticles presents lower drug accumulation than free celastrol in off-target organs and tissues, thereby minimizing celastrol-related systemic toxicity. Celastrol-albumin nanoparticles thus represents a promising treatment option for mesangioproliferative glomerulonephritis and similar glomerular diseases.Mesangial cell-mediated glomerulonephritis is a frequent cause of kidney disease. Here the authors show that celastrol loaded in albumin nanoparticles efficiently targets mesangial cells, and is effective in rat models.

The evolution of obscured AGN

NASA Astrophysics Data System (ADS)

Brightman, Murray

2012-09-01

We present results on the evolution of Compton thick AGN with redshift, and the nature of this obscuration, important for understanding the accretion history of the universe and for AGN unification schemes. We use lessons learned from spectral complexity of local AGN (Brightman & Nandra 2012) and up to date spectral models of heavily absorbed AGN, which take into account Compton scattering, self consistent Fe Ka modeling and the geometry of the circumnuclear material (Brightman & Nandra 2011), to optimise our identification of Compton thick AGN and understanding of the obscuring material. Results from the Chandra Deep Field South are presented (Brightman & Ueda, 2012), which show an increasing fraction of CTAGN with redshift and that most heavily obscured AGN are geometrically deeply buried in material, as well as new results from and extension of this study to AEGIS-XD and Chandra-COSMOS survey, which aim to fully characterise the dependence of heavy AGN obscuration on redshift and luminosity.

BAT AGN Spectroscopic Survey. I. Spectral Measurements, Derived Quantities, and AGN Demographics

NASA Astrophysics Data System (ADS)

Koss, Michael; Trakhtenbrot, Benny; Ricci, Claudio; Lamperti, Isabella; Oh, Kyuseok; Berney, Simon; Schawinski, Kevin; Baloković, Mislav; Baronchelli, Linda; Crenshaw, D. Michael; Fischer, Travis; Gehrels, Neil; Harrison, Fiona; Hashimoto, Yasuhiro; Hogg, Drew; Ichikawa, Kohei; Masetti, Nicola; Mushotzky, Richard; Sartori, Lia; Stern, Daniel; Treister, Ezequiel; Ueda, Yoshihiro; Veilleux, Sylvain; Winter, Lisa

2017-11-01

We present the first catalog and data release of the Swift-BAT AGN Spectroscopic Survey. We analyze optical spectra of the majority of the detected AGNs (77%, 642/836)based on their 14-195 keV emission in the 70-month Swift-BAT all-sky catalog. This includes redshift determination, absorption and emission-line measurements, and black hole mass and accretion rate estimates for the majority of obscured and unobscured AGNs (74%, 473/642), with 340 measured for the first time. With ˜90% of sources at z< 0.2, the survey represents a significant advance in the census of hard X-ray-selected AGNs in the local universe. In this first catalog paper, we describe the spectroscopic observations and data sets, and our initial spectral analysis. The FWHMs of the emission lines show broad agreement with the X-ray obscuration (˜94%), such that Sy 1-1.8 have {N}{{H}}< {10}21.9 cm-2, and Seyfert 2 have {N}{{H}}> {10}21.9 cm-2. Seyfert 1.9, however, show a range of column densities. Compared to narrow-line AGNs in the SDSS, the X-ray-selected AGNs have a larger fraction of dusty host galaxies ({{H}}α /{{H}}β > 5), suggesting that these types of AGN are missed in optical surveys. Using the [O III] λ5007/Hβ and [N II] λ6583/Hα emission-line diagnostic, about half of the sources are classified as Seyferts; ˜15% reside in dusty galaxies that lack an Hβ detection, but for which the upper limits on line emission imply either a Seyfert or LINER, ˜ 15 % are in galaxies with weak or no emission lines despite high-quality spectra, and a few percent each are LINERS, composite galaxies, H II regions, or in known beamed AGNs.

[Outcome of rapidly progressive glomerulonephritis post-streptococcal disease in children].

PubMed

Jellouli, Manel; Maghraoui, Sondos; Abidi, Kamel; Hammi, Yosra; Goucha, Rim; Naija, Ouns; Zarrouk, Chokri; Gargah, Tahar

2015-11-01

Rapidly progressive glomerulonephritis is a rare form of postinfectious glomerulonephritis. The aim of this study was to describe the outcome of our patients with severe post-streptococcal glomerulonephritis. This retrospective study was conducted in the department of pediatrics in Charles-Nicolle Hospital during a period of 13 years (1997-2009). Twenty-seven children were identified. The mean age was 8.7 years. All patients presented renal failure at presentation. The mean serum creatinine at presentation was 376.9 μmol/L. Six patients presented nephrotic syndrome. Twenty-six children had renal biopsies. Renal biopsies showed crescents in 24 cases. Eighteen children received pulse dose of corticosteroids (66.6%) and 6 children (22%) received pulse dose of corticosteroids and cyclophosphamide. Eleven patients required dialysis. At last follow-up, 22 patients (81.5%) had normal kidney function, 2 had renal dysfunction and 3 reached end stage renal disease. The only significant determinant for renal survival was the supportive dialysis (P=0.015). Rapidly progressive glomerulonephritis is uncommon. There have been significant advancements in supportive, as well as specific therapy, but the outcome continues to be poor. Copyright © 2015 Association Société de néphrologie. Published by Elsevier SAS. All rights reserved.

Massive outflow properties suggest AGN fade slowly

NASA Astrophysics Data System (ADS)

Zubovas, Kastytis

2018-01-01

Massive large-scale active galactic nucleus (AGN) outflows are an important element of galaxy evolution, being a way through which the AGN can affect most of the host galaxy. However, outflows evolve on time-scales much longer than typical AGN episode durations, therefore most AGN outflows are not observed simultaneously with the AGN episode that inflated them. It is therefore remarkable that rather tight correlations between outflow properties and AGN luminosity exist. In this paper, I show that such correlations can be preserved during the fading phase of the AGN episode, provided that the AGN luminosity evolves as a power law with exponent αd ∼ 1 at late times. I also show that subsequent AGN episodes that illuminate an ongoing outflow are unlikely to produce outflow momentum or energy rates rising above the observed correlations. However, there may be many difficult-to-detect outflows with momentum and energy rates lower than expected from the current AGN luminosity. Detailed observations of AGN outflow properties might help constrain the activity histories of typical and/or individual AGN.

AGN Clustering in the BAT Sample

NASA Astrophysics Data System (ADS)

Powell, Meredith; Cappelluti, Nico; Urry, Meg; Koss, Michael; BASS Team

2018-01-01

We characterize the environments of local growing supermassive black holes by measuring the clustering of AGN in the Swift-BAT Spectroscopic Survey (BASS). With 548 AGN in the redshift range 0.01AGN to date due to its hard X-ray selection (14-195 keV). By measuring the projected cross-correlation function between the AGN and 2MASS galaxies, we constrain the halo occupation distribution (HOD) of the full sample with unprecedented sensitivity, as well as in bins of obscuration with matched luminosity distributions. In doing so, we find that AGN tend to reside in galaxy groups, agreeing with previous studies of AGN throughout a large range of luminosity and redshift. We also find evidence that obscured AGN tend to reside in denser environments than unobscured AGN.

Membranoproliferative glomerulonephritis and acute renal failure in a patient with chronic lymphocytic leukemia: Response to obinutuzumab.

PubMed

Jain, Punit; Kanagal-Shamanna, Rashmi; Wierda, William; Ferrajoli, Alessandra; Keating, Michael; Jain, Nitin

2017-09-01

Membranoproliferative glomerulonephritis (MPGN) is a common extramedullary renal presentation in chronic lymphocytic leukemia (CLL) and can present with either a frank renal failure or proteinuria. One of its etiologies has been attributed to a paraneoplastic, immune complex phenomenon occurring in CLL. Although there is no standard of care in such patients, use of anti-CD20 monoclonal antibodies like rituximab have been used before in such patients with variable responses. Obinutuzumab is a novel, type II, immunoglobulin-G1 monoclonal antibody with a higher efficacy than rituximab and has an established safely profile in patients with comorbidities and poor renal functions. There are no such reported cases of MPGN in CLL being treated with obinutuzumab. We used the standard doses of obinutuzumab in our elderly patient (78-year-old woman) with high-risk CLL due to an underlying TP53 mutation, along with a MPGN-related acute renal failure. The patient achieved complete remission after six cycles of obinutuzumab; however, she remained positive for minimal residual disease on flow cytometry. Her renal function improved completely, suggesting a complete response of her underlying MPGN. Obinutuzumab has an established safety profile in patients with CLL, but our case is the first reported case of a paraneoplastic, immune complex-mediated MPGN in CLL being treated with obinutuzumab. Obinutuzumab should be explored as a potential option in patients with CLL and MPGN. Copyright © 2016 King Faisal Specialist Hospital & Research Centre. Published by Elsevier B.V. All rights reserved.

Urinary cystatin C as a renal biomarker and its immunohistochemical localization in anti-GBM glomerulonephritis rats.

PubMed

Togashi, Yuko; Imura, Naoko; Miyamoto, Yohei

2013-11-01

The usefulness of urinary cystatin C for the early detection of renal damage in anti-glomerular basement membrane (GBM) glomerulonephritis rats was investigated and compared to other biomarkers (β2-microglobulin, calbindin, clusterin, epidermal growth factor (EGF), alpha-glutathione S-transferase (GST-α), mu-glutathione S-transferase (GST-μ), kidney injury molecule-1 (KIM-1), neutrophil gelatinase-associated lipocalin (NGAL), osteopontin, tissue inhibitor of metalloprotease-1 (TIMP-1), and vascular endothelial growth factor (VEGF)). Urinary levels of cystatin C increased in anti-GBM glomerulonephritis rats, whereas the conventional markers, plasma creatinine and UN did not, demonstrating its usefulness for the early detection of renal damage associated with anti-GBM glomerulonephritis. As well as cystatin C, urinary β2-microglobulin, clusterin, GST-α, GST-μ, KIM-1, and NGAL also had the potential to detect renal damage associated with anti-GBM glomerulonephritis. Furthermore, the immunohistochemical localization of cystatin C in the kidney was examined. Cystatin C expression was mainly observed in the proximal renal tubules in anti-GBM glomerulonephritis rats, and its expression barely changed with the progression of glomerulonephritis. Cystatin C expression was also observed in the tubular lumen of the cortex and medulla when glomerulonephritis was marked, which was considered to be characteristic of renal damage. In conclusion, urinary cystatin C, β2-microglobulin, clusterin, GST-α, GST-μ, KIM-1, and NGAL could be useful biomarkers of renal damage in anti-GBM glomerulonephritis rats. Immunohistochemical cystatin C expression in the proximal renal tubules was barely changed by the progression of glomerulonephritis, but it was newly observed in the tubular lumen when renal damage was apparent. Crown Copyright © 2013. Published by Elsevier GmbH. All rights reserved.

Neutrinos from AGN

NASA Technical Reports Server (NTRS)

Kazanas, Demosthenes; White, Nicholas E. (Technical Monitor)

2000-01-01

The great penetrating power of neutrinos makes them ideal probe of astrophysical sites and conditions inaccessible to other forms of radiation. These are the centers of stars (collapsing or not) and the centers of Active Galactic Nuclei (AGN). It has been suggested that AGN presented a very promising source of high energy neutrinos, possibly detectable by underwater neutrino detectors. This paper reviews the evolution of ideas concerning the emission of neutrinos from AGN in view of the more recent developments in gamma-ray astronomy and their implications for the neutrino emission from these class of objects.

Steps Toward Unveiling the True Population of AGN: Photometric Selection of Broad-Line AGN

NASA Astrophysics Data System (ADS)

Schneider, Evan; Impey, C.

2012-01-01

We present an AGN selection technique that enables identification of broad-line AGN using only photometric data. An extension of infrared selection techniques, our method involves fitting a given spectral energy distribution with a model consisting of three physically motivated components: infrared power law emission, optical accretion disk emission, and host galaxy emission. Each component can be varied in intensity, and a reduced chi-square minimization routine is used to determine the optimum parameters for each object. Using this model, both broad- and narrow-line AGN are seen to fall within discrete ranges of parameter space that have plausible bounds, allowing physical trends with luminosity and redshift to be determined. Based on a fiducial sample of AGN from the catalog of Trump et al. (2009), we find the region occupied by broad-line AGN to be distinct from that of quiescent or star-bursting galaxies. Because this technique relies only on photometry, it will allow us to find AGN at fainter magnitudes than are accessible in spectroscopic surveys, and thus probe a population of less luminous and/or higher redshift objects. With the vast availability of photometric data in large surveys, this technique should have broad applicability and result in large samples that will complement X-ray AGN catalogs.

The WISE AGN Catalog

NASA Astrophysics Data System (ADS)

Assef, R. J.; Stern, D.; Noirot, G.; Jun, H. D.; Cutri, R. M.; Eisenhardt, P. R. M.

2018-02-01

We present two large catalogs of active galactic nucleus (AGN) candidates identified across 30,093 deg2 of extragalactic sky from the Wide-field Infrared Survey Explorer’s AllWISE Data Release. Both catalogs are selected purely using the Wide-field Infrared Survey Explorer (WISE) W1 and W2 bands. The R90 catalog consists of 4,543,530 AGN candidates with 90% reliability, while the C75 catalog consists of 20,907,127 AGN candidates with 75% completeness. These reliability and completeness figures were determined from a detailed analysis of UV- to near-IR spectral energy distributions of ∼ {10}5 sources in the 9 deg2 Boötes field. The AGN selection criteria are based on those of Assef et al. (2013) recalibrated to the AllWISE data release. We provide a detailed discussion of potential artifacts and excise portions of the sky close to the Galactic Center, Galactic Plane, nearby galaxies, and other expected contaminating sources. These catalogs are expected to enable a broad range of science, and we present a few illustrative cases. From the R90 sample, we identify 45 highly variable AGNs lacking radio counterparts in the FIRST survey. One of these sources, WISEA J142846.71+172353.1, is a changing-look quasar at z = 0.104, which has changed from having broad Hα to being a narrow-lined AGN. We characterize our catalogs by comparing them to large, wide-area AGN catalogs in the literature. We identify four ROSAT X-ray sources that are each matched to three WISE-selected AGNs in the R90 sample within 30″. Spectroscopy reveals that one of these systems, 2RXS J150158.6+691029, consists of a triplet of quasars at z = 1.133 ± 0.004, suggestive of a rich group or forming galaxy cluster.

AGN Luminosity and Stellar Age: Two Missing Ingredients for AGN Unification as Seen with iPTF Supernovae

NASA Astrophysics Data System (ADS)

Villarroel, Beatriz; Nyholm, Anders; Karlsson, Torgny; Comerón, Sébastien; Korn, Andreas J.; Sollerman, Jesper; Zackrisson, Erik

2017-03-01

Active galactic nuclei (AGNs) are extremely powerful cosmic objects, driven by accretion of hot gas upon super-massive black holes. The zoo of AGN classes is divided into two major groups, with Type-1 AGNs displaying broad Balmer emission lines and Type-2 narrow ones. For a long time it was believed that a Type-2 AGN is a Type-1 AGN viewed through a dusty kiloparsec-sized torus, but an emerging body of observations suggests more than just the viewing angle matters. Here we report significant differences in supernova (SN) counts and classes in the first study to date of SNe near Type-1 and Type-2 AGN host galaxies, using data from the intermediate Palomar Transient Factory, the Sloan Digital Sky Survey Data Release 7, and Galaxy Zoo. We detect many more SNe in Type-2 AGN hosts (size of effect ˜5.1σ) compared to Type-1 hosts, which shows that the two classes of AGN are located inside host galaxies with different properties. In addition, Type-1 and Type-2 AGNs that are dominated by star formation according to Wide-field Infrared Survey Explorer colors {m}W1-{m}W2< 0.5 and are matched in 22 μm absolute magnitude differ by a factor of ten in L[O III] λ5007 luminosity, suggesting that when residing in similar types of host galaxies Type-1 AGNs are much more luminous. Our results demonstrate two more factors that play an important role in completing the current picture: the age of stellar populations and the AGN luminosity. This has immediate consequences for understanding the many AGN classes and galaxy evolution.

Properties of Low-mass AGN as They Relate to Unification and Massive AGN

NASA Astrophysics Data System (ADS)

Hood, Carol E.

2011-01-01

Current unification models of AGN suggest the observational differences between Type 1 and Type 2 objects are solely due to the orientation angle of the object. Observations have proved consistent with predictions and continue to strengthen the case for unification, however, many are still searching for "true" Type 2 objects, including predictions of their formation due to low luminosity or low accretion rate. Low-mass (< 106solar masses) AGN provide interesting environments in which these unification models can be studied. We also aim to compare the properties of low-mass AGN with their more massive counterparts to look for structural similarities and differences over a more substantial range of luminosities and accretion rates than previously studied. We present an in-depth multi-wavelength study of one of the prototypical low-mass AGN, POX 52, investigating the properties of the central engine along with that of the host galaxy. This includes data from the VLA, Spitzer, 2MASS, HST, GALEX, XMM, and Chandra, providing us with one of the most comprehensive looks into low-mass AGN. Unlike the other prototypical low-mass AGN, NGC 4395, POX 52 resides in a dwarf elliptical galaxy, accreting at ≈ 0.35 the Eddington limit. Additionally, we examine a sample 41 Type 1 and Type 2 objects, including POX 52 and NGC 4395, with the Spitzer IRS and a sub-sample of those with XMM to study the absorption properties of low-mass AGN, to test the validity of unification models in the low-mass regime, and to investigate possible structural differences between objects with low and high mass black holes and accretion rates. We will discuss the IR spectral shape and present emission-line diagnostics for Type 1 and Type 2 AGNs at low masses.

[Glomerulonephritis and vasculitis as causes of arterial hypertension].

PubMed

Eicken, Sibylle; Gugger, Mathias; Marti, Hans-Peter

2012-05-01

The various types of glomerulonephritis, including many forms of vasculitis, are responsible for about 15% of cases of end-stage renal disease (ESRD). Arterial hypertension represents a frequent finding in patients suffering from glomerulonephritis or vasculitis and hypertension also serves as an indicator for these severe types of diseases. In addition, there are symptoms and signs like hematuria, proteinuria and renal failure. Especially, rapidly progressive glomerulonephritis (RPGN) constitutes a medical emergency and must not be missed by treating physicians. This disease can either occur limited to the kidneys or in the context of a systemic inflammatory disorder, like a vasculitis. If left untreated, RPGN can lead to a necrotizing destruction of glomeruli causing irreversible kidney damage within several months or even weeks. With respect to the immunologically caused vasculitis, there are - depending upon the severity and type of organ involved - many clinical warning signs to be recognized, such as arterial hypertension, hemoptysis, arthalgias, muscle pain, palpable purpura, hematuria, proteinuria and renal failure. In addition, constitutional signs, such as fever and loss of body weight may occur concurrently. Investigations of glomerulonephritis or vasculitis must contain a careful and complete examination of family history and medications used by the respective patient. Thereafter, a thorough clinical examination must follow, including skin, joints and measurement of arterial blood pressure. In addition, a spectrum of laboratory analyses is required in blood, such as full blood screen, erythrocyte sedimentation rate, CRP, creatinine, urea and glucose, and in urine, including urinalysis looking for hematuria, red cell casts and proteinuria. Importantly, proteinuria needs to be quantified by the utilization of a random urine sample. Proteinuria > 3g/d is diagnostic for a glomerular damage. These basic tests are usually followed by more specialized analyses

Longterm AGN variability in the BASS sample

NASA Astrophysics Data System (ADS)

Sartori, Lia; Schawinski, Kevin; Koss, Michael; Treister, Ezequiel

2018-01-01

The study of AGN variability on different timescales can provide important information about black hole accretion physics, as well as the black hole – host galaxy interaction and coevolution. Galaxies with extended AGN photoionised clouds, e.g. IC 2497 and “Hanny’s Voorwerp”, are a great laboratory to study AGN variability over 100 kyr timescales, especially in the case where the AGN is currently dropping in luminosity. Based on a large sample of optically elusive AGN in the BASS sample we suggest that AGN may ‘flicker’ on and off 100-1000 times on ~10^5 yr timescales, and that optically elusive AGN may provide information about the switching on phase. In this talk I will show how longslit and IFU observations of BASS sources, combined with high quality hard X-ray observations and black hole demographic information, can help constraining the AGN lifecycle, and ultimately what is the physics driving AGN variability.

Accretion Rate: An Axis Of Agn Unification

NASA Astrophysics Data System (ADS)

Trump, Jonathan R.; Impey, C. D.; Kelly, B. C.

2011-01-01

We show how accretion rate governs the physical properties of broad-line, narrow-line, and lineless active galactic nuclei (AGNs). We avoid the systematic errors plaguing previous studies of AGN accretion rate by using accurate accretion luminosities from well-sampled multiwavelength SEDs from the Cosmic Evolution Survey (COSMOS), and accurate black hole masses derived from virial scaling relations (for broad-line AGNs) or host-AGN relations (for narrow-line and lineless AGNs). In general, broad emission lines are present only at the highest accretion rates (L/L_Edd>0.01), and these rapidly accreting AGNs are observed as broad-line AGNs or possibly as obscured narrow-line AGNs. Narrow-line and lineless AGNs at lower specific accretion rates (L/L_Edd<0.01) are unobscured and yet lack a broad line region. The disappearance of the broad emission lines is caused by an expanding radiatively inefficient accretion flow (RIAF) at the inner radius of the accretion disk. The presence of the RIAF also drives L/L_Edd<0.01 narrow-line and lineless AGNs to be 10-100 times more radio-luminous than broad-line AGNs, since the unbound nature of the RIAF means it is easier to form a radio outflow. The IR torus signature also tends to become weaker or disappear from L/L_Edd<0.01 AGNs, although there may be additional mid-IR synchrotron emission associated with the RIAF. Together these results suggest that specific accretion rate is an important physical "axis" of AGN unification, described by a simple model.

Gene expression profiling of anti-GBM glomerulonephritis model: the role of NF-kappaB in immune complex kidney disease.

PubMed

Kim, Ju Han; Ha, Il Soo; Hwang, Chang-Il; Lee, Young-Ju; Kim, Jihoon; Yang, Seung-Hee; Kim, Yon Su; Cao, Yun Anna; Choi, Sangdun; Park, Woong-Yang

2004-11-01

Immune complexes may cause an irreversible onset of chronic renal disease. Most patients with chronic renal disease undergo a final common pathway, marked by glomerulosclerosis and interstitial fibrosis. We attempted to draw a molecular map of anti-glomerular basement membrane (GBM) glomerulonephritis in mice using oligonucleotide microarray technology. Kidneys were harvested at days 1, 3, 7, 11, and 16 after inducing glomerulonephritis by using anti-GBM antibody. In parallel with examining the biochemical and histologic changes, gene expression profiles were acquired against five pooled control kidneys. Gene expression levels were cross-validated by either reverse transcription-polymerase chain reaction (RT-PCR), real-time PCR, or immunohistochemistry. Pathologic changes in anti-GBM glomerulonephritis were confirmed in both BALB/c and C57BL/6 strains. Among the 13,680 spotted 65mer oligonucleotides, 1112 genes showing significant temporal patterns by permutation analysis of variance (ANOVA) with multiple testing correction [false discovery ratio (FDR) < 0.05] were chosen for cluster analysis. From the expression profile, acute inflammatory reactions characterized by the elevation of various cytokines, including interleukin (IL)-1 and IL-6, were identified within 3 days of disease onset. After 7 days, tissue remodeling response was prominent with highly induced extracellular-matrix (ECM) genes. Although cytokines related to lymphocyte activation were not detected, monocyte or mesangial cell proliferation-related genes were increased. Tumor necrosis factor-alpha (TNF-alpha) and nuclear factor-kappaB (NF-kappaB) pathway were consistently activated along the entire disease progression, inducing various target genes like complement 3, IL-1b, IL-6, Traf1, and Saa1. We made a large-scale gene expression time table for mouse anti-GBM glomerulonephritis model, providing a comprehensive overview on the mechanism governing the initiation and the progression of inflammatory

The BAT AGN Spectroscopic Survey (BASS)

NASA Astrophysics Data System (ADS)

Koss, Michael

2017-08-01

We present the Swift BAT AGN Spectroscopic Survey (BASS) and discus the first four papers. The catalog represents an unprecedented census of hard-X-ray selected AGN in the local universe, with ~90% of sources at z<0.2. Starting from an all-sky catalog of AGN detected based on their 14-195 keV flux from the 70-month Swift/BAT catalog, we analyze a total of 1279 optical spectra, taken from twelve different telescopes, for a total of 642 spectra of unique AGN. We present the absorption and emission line measurements as well as black hole masses and accretion rates for the majority of obscured and un-obscured AGN (473), representing more than a factor of 10 increase from past studies. Consistent with previous surveys, we find an increase in the fraction of un-obscured (type 1) AGN, as measured from broad Hbeta and Halpha, with increasing 14-195 keV and 2-10 keV luminosity. We find the FWHM of the emission lines to show broad agreement with the X-ray obscuration measurements. Compared to narrow line AGN in the SDSS, the X-ray selected AGN in our sample with emission lines have a larger fraction of dustier galaxies suggesting these types of galaxies are missed in optical AGN surveys using emission line diagnostics.

Heavily Obscured AGN with SIMBOL-X

NASA Astrophysics Data System (ADS)

Della Ceca, R.; Caccianiga, A.; Severgnini, P.

2009-05-01

By comparing an optically selected sample of narrow lines AGN with an X-ray selected sample of AGN we have recently derived an estimate of the intrinsic (i.e. before absorption) 2-10 keV luminosity function (XLF) of Compton Thick AGNs. We will use this XLF to derive the number of Compton Thick AGN that will be found in the SIMBOL-X survey(s).

Compton thick AGN: the hunt continues

NASA Astrophysics Data System (ADS)

Marchesi, Stefano

2017-09-01

The X-ray spectral analysis of Compton thick (CT-) active galactic nuclei (AGN) represents a fundamental step to understand the physics of the obscuring material surrounding the accreting supermassive black hole. However, at the present day CT-AGN remain extremely hard to detect. After a first, successful pilot program, we propose to target with a 10 ks Chandra observation 4 low redshift candidate CT-AGN from the Swift-BAT 100-month catalog. This analysis will refine our knowledge of the selection function of CT-AGN, therefore helping us in determine the true intrinsic fraction of CT-AGN and their contribution to the CXB.

Antineutrophil cytoplasmic antibody-negative pauci-immune crescentic glomerulonephritis associated with rheumatoid arthritis: An unusual case report.

PubMed

Hsieh, Hsiu-Shin; Chang, Chao-Fu; Yang, An-Han; Kuo, Hsiao-Ling; Yang, Wu-Chang; Lin, Chih-Ching

2003-10-01

Clinically relevant renal lesions in rheumatoid arthritis (RA) are not common. More often renal involvement is related to complications of therapy than the disease itself. The most common forms of primary renal disease in RA are membranous glomerulonephropathy and a pure mesangial proliferative glomerulonephritis. Some studies have described the association between crescentic glomerulonephritis (crescentic GN) and RA, but they were all found to be perinuclear antineutrophil cytoplasmic antibody (p-ANCA) positive. However, RA associated with ANCA negative pauci-immue crescentic GN has not been reported. This is a case report of a 37-year-old female with RA who initially presented with general oedema and acute deterioration of renal function. The renal biopsy revealed ANCA negative pauci-immune crescentic GN. The patient was treated with steroid pulse and plasmapheresis, but not cyclophosphamide because of severe urosepsis. Despite the use of aggressive therapy, her renal function was not improved and she underwent maintenance haemodialysis thereafter. Because ANCA negative crescentic GN may occur in RA patients without frank systemic vasculitis, but with severe clinical manifestation, a heightened suspicion for a relatively 'silent' crescentic GN would have led to the correct diagnosis and appropriate treatment.

The BAT AGN Spectroscopic Survey (BASS)

NASA Astrophysics Data System (ADS)

Koss, Michael; Trakhtenbrot, Benny; Ricci, Claudio; Lamperti, Isabella; Oh, Kyuseok; Berney, Simon; Schawinski, Kevin; Balokovic, Mislav; Baronchelli, Linda; Gehrels, Neil; Stern, Daniel; Mushotzky, Richard; Veilleux, Sylvain; Ueda, Yoshihiro; Crenshaw, D. Michael; Harrison, Fiona; Fischer, Travis C.; Treister, Ezequiel; BASS Team; Swift BAT Team

2017-01-01

We present the Swift BAT AGN Spectroscopic Survey (BASS) and discus the first four papers. The catalog represents an unprecedented census of hard-X-ray selected AGN in the local universe, with ~90% of sources at z<0.2. Starting from an all-sky catalog of AGN detected based on their 14-195 keV flux from the 70-month Swift/BAT catalog, we analyze a total of 1279 optical spectra, taken from twelve dierent telescopes, for a total of 642 spectra of unique AGN. We present the absorption and emission line measurements as well as black hole masses and accretion rates for the majority of obscured and un-obscured AGN (473), representing more than a factor of 10 increase from past studies. Consistent with previous surveys, we find an increase in the fraction of un-obscured (type 1) AGN, as measured from broad Hbeta and Halpha, with increasing 14-195 keV and 2-10 keV luminosity. We find the FWHM of the emission lines to show broad agreement with the X-ray obscuration measurements. Compared to narrow line AGN in the SDSS, the X-ray selected AGN in our sample with emission lines have a larger fraction of dustier galaxies suggesting these types of galaxies are missed in optical AGN surveys using emission line diagnostics. Additionally, we discuss follow-on efforts to study the variation of [OIII] to Xray measurements, a new method to measure accretion rates from using line ratios, a sample of 100 AGN observed with NIR spectroscopy, and an effort to measure the accretion rates and obscuration with merger stage in a subsample of mergers.

AGN Variability in the GOODS Fields

NASA Astrophysics Data System (ADS)

Sarajedini, Vicki

2007-07-01

Variability is a proven method to identify intrinsically faint active nuclei in galaxies found in deep HST surveys. We propose to extend our short-term variability study of the GOODS fields to include the more recent epochs obtained via supernovae searchers, increasing the overall time baseline from 6 months to 2.5 years. Based on typical AGN lightcurves, we expect to detect 70% more AGN by including these more recent epochs. Variable-detected AGN samples complement current X-ray and mid-IR surveys for AGN by providing unambigous evidence of nuclear activity. Additionallty, a significant number of variable nuclei are not associated with X-ray or mid-IR sources and would thus go undetected. With the increased time baseline, we will be able to construct the structure function {variability amplitude vs. time} for low-luminosity AGN to z 1. The inclusion of the longer time interval will allow for better descrimination among the various models describing the nature of AGN variability. The variability survey will be compared against spectroscopically selected AGN from the Team Keck Redshift Survey of the GOODS-N and the upcoming Flamingos-II NIR survey of the GOODS-S. The high-resolution ACS images will be used to separate the AGN from the host galaxy light and study the morphology, size and environment of the host galaxy. These studies will address questions concerning the nature of low-luminosity AGN evolution and variability at z 1.

Frequency of familial Mediterranean fever (MEFV) gene mutations in patients with biopsy-proven primary glomerulonephritis.

PubMed

Huzmeli, Can; Candan, Ferhan; Bagci, Gokhan; Alaygut, Demet; Yilmaz, Ali; Gedikli, Asim; Bagci, Binnur; Timucin, Meryem; Sezgin, Ilhan; Kayatas, Mansur

2017-11-01

Primary glomerulopathies are those disorders that affect glomerular structure, function, or both in the absence of a multisystem disorder. We aimed to evaluate the frequency of MEFV gene mutation to show possible coexistence of FMF in patients diagnosed with biopsy-proven primary glomerulonephritis (GN). A total of 64 patients with biopsy-proven primary GN were included in the study. MEFV gene mutations examined retrospectively. The mean age of patients was 39.6 ± 13.4 (range 18-69), 35 of patients were female and 29 of patients were male. Of the 64 patients, 17 were mesangial proliferative glomerulonephritis (MsPGN), 15 were IgA nephropathy (IgAN), 12 were membranous glomerulonephritis (MGN), 11 were focal segmental glomerulosclerosis (FSGS), three were membranous proliferative glomerulonephritis (MPGN), three were immune complex glomerulonephritis (ICGN), two were minimal change disease (MCD), and one was IgM nephropathy (IgMN). MEFV gene mutation was detected in 35.9% (23) of these patients. The most frequently detected mutations were E148Q and M694V. Twelve cases (18.75% of GN patients) with MEFV gene mutation were diagnosed as FMF phenotype I. The frequency of MEFV gene mutation was detected at a high rate of 35.9%. Further studies with larger populations are needed to clarify the importance of these mutations on clinical progression of glomerulonephritis.

Classifying murine glomerulonephritis using optical coherence tomography and optical coherence elastography.

PubMed

Liu, Chih-Hao; Du, Yong; Singh, Manmohan; Wu, Chen; Han, Zhaolong; Li, Jiasong; Chang, Anthony; Mohan, Chandra; Larin, Kirill V

2016-08-01

Acute glomerulonephritis caused by antiglomerular basement membrane marked by high mortality. The primary reason for this is delayed diagnosis via blood examination, urine analysis, tissue biopsy, or ultrasound and X-ray computed tomography imaging. Blood, urine, and tissue-based diagnoses can be time consuming, while ultrasound and CT imaging have relatively low spatial resolution, with reduced sensitivity. Optical coherence tomography is a noninvasive and high-resolution imaging technique that provides superior spatial resolution (micrometer scale) as compared to ultrasound and CT. Changes in tissue properties can be detected based on the optical metrics analyzed from the OCT signals, such as optical attenuation and speckle variance. Furthermore, OCT does not rely on ionizing radiation as with CT imaging. In addition to structural changes, the elasticity of the kidney can significantly change due to nephritis. In this work, OCT has been utilized to quantify the difference in tissue properties between healthy and nephritic murine kidneys. Although OCT imaging could identify the diseased tissue, its classification accuracy is clinically inadequate. By combining optical metrics with elasticity, the classification accuracy improves from 76% to 95%. These results show that OCT combined with OCE can be a powerful tool for identifying and classifying nephritis. Therefore, the OCT/OCE method could potentially be used as a minimally invasive tool for longitudinal studies during the progression and therapy of glomerulonephritis as well as complement and, perhaps, substitute highly invasive tissue biopsies. Elastic-wave propagation in mouse healthy and nephritic kidneys. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

AGN Unification at z ~ 1: u - R Colors and Gradients in X-Ray AGN Hosts

NASA Astrophysics Data System (ADS)

Ammons, S. Mark; Rosario, David J. V.; Koo, David C.; Dutton, Aaron A.; Melbourne, Jason; Max, Claire E.; Mozena, Mark; Kocevski, Dale D.; McGrath, Elizabeth J.; Bouwens, Rychard J.; Magee, Daniel K.

2011-10-01

We present uncontaminated rest-frame u - R colors of 78 X-ray-selected active galactic nucleus (AGN) hosts at 0.5 < z < 1.5 in the Chandra Deep Fields measured with Hubble Space Telescope (HST)/Advanced Camera for Surveys/NICMOS and Very Large Telescope/ISAAC imaging. We also present spatially resolved NUV - R color gradients for a subsample of AGN hosts imaged by HST/Wide Field Camera 3 (WFC3). Integrated, uncorrected photometry is not reliable for comparing the mean properties of soft and hard AGN host galaxies at z ~ 1 due to color contamination from point-source AGN emission. We use a cloning simulation to develop a calibration between concentration and this color contamination and use this to correct host galaxy colors. The mean u - R color of the unobscured/soft hosts beyond ~6 kpc is statistically equivalent to that of the obscured/hard hosts (the soft sources are 0.09 ± 0.16 mag bluer). Furthermore, the rest-frame V - J colors of the obscured and unobscured hosts beyond ~6 kpc are statistically equivalent, suggesting that the two populations have similar distributions of dust extinction. For the WFC3/infrared sample, the mean NUV - R color gradients of unobscured and obscured sources differ by less than ~0.5 mag for r > 1.1 kpc. These three observations imply that AGN obscuration is uncorrelated with the star formation rate beyond ~1 kpc. These observations favor a unification scenario for intermediate-luminosity AGNs in which obscuration is determined geometrically. Scenarios in which the majority of intermediate-luminosity AGNs at z ~ 1 are undergoing rapid, galaxy-wide quenching due to AGN-driven feedback processes are disfavored.

The BAT AGN Spectroscopic Survey (BASS) DR1-Spectral Measurements, Derived Quantities, and AGN Demographics

NASA Astrophysics Data System (ADS)

Koss, Michael; BASS Team

2018-01-01

We present the first catalog and data release of the Swift-BAT AGN Spectroscopic Survey (BASS). We analyze optical spectra of the majority of AGN (77%, 641/836) detected based on their 14-195 keV emission in the 70-month Swift BAT all-sky catalog. This includes redshift determination, absorption and emission line measurements, and black hole mass and accretion rate estimates for the majority of obscured and un-obscured AGN (74%, 473/641) with 340 measured for the first time. With ~90% of sources at z<0.2, the survey represents a significant census of hard-X-ray selected AGN in the local universe. In this first catalog paper, we describe the spectroscopic observations and datasets, and our initial spectral analysis. The FWHM of the emission lines show broad agreement with the X-ray obscuration (~94%), such that Sy 1-1.8 have NH<10^21.9 cm^-2, and Seyfert 2, have NH>10^21.9 cm^-2. Seyfert 1.9 show a range of column densities. Compared to narrow line AGN in the SDSS, the X-ray selected AGN have a larger fraction of dusty host galaxies suggesting these types of AGN are missed in optical surveys. Using the most sensitive [OIII]/Hbeta and [NII]/Halpha emission line diagnostic, about half of the sources are classified as Seyferts, ~15% reside in dusty galaxies that lack an Hbeta detection, but for which the line upper limits imply either a Seyfert or LINER, ~15% are in galaxies with weak or no emission lines despite high quality spectra, and a few percent each are LINERS, composite galaxies, HII regions, or in known beamed AGN.

Density profile of dark matter haloes and galaxies in the HORIZON-AGN simulation: the impact of AGN feedback

NASA Astrophysics Data System (ADS)

Peirani, Sébastien; Dubois, Yohan; Volonteri, Marta; Devriendt, Julien; Bundy, Kevin; Silk, Joe; Pichon, Christophe; Kaviraj, Sugata; Gavazzi, Raphaël; Habouzit, Mélanie

2017-12-01

Using a suite of three large cosmological hydrodynamical simulations, HORIZON-AGN, HORIZON–NOAGN (no AGN feedback) and HORIZON-DM (no baryons), we investigate how a typical sub-grid model for AGN feedback affects the evolution of the inner density profiles of massive dark matter haloes and galaxies. Based on direct object-to-object comparisons, we find that the integrated inner mass and density slope differences between objects formed in these three simulations (hereafter, HAGN, HnoAGN and HDM) significantly evolve with time. More specifically, at high redshift (z ∼ 5), the mean central density profiles of HAGN and HnoAGN dark matter haloes tend to be much steeper than their HDM counterparts owing to the rapidly growing baryonic component and ensuing adiabatic contraction. By z ∼ 1.5, these mean halo density profiles in HAGN have flattened, pummelled by powerful AGN activity ('quasar mode'): the integrated inner mass difference gaps with HnoAGN haloes have widened, and those with HDM haloes have narrowed. Fast forward 9.5 billion years, down to z = 0, and the trend reverses: HAGN halo mean density profiles drift back to a more cusped shape as AGN feedback efficiency dwindles ('radio mode'), and the gaps in integrated central mass difference with HnoAGN and HDM close and broaden, respectively. On the galaxy side, the story differs noticeably. Averaged stellar profile central densities and inner slopes are monotonically reduced by AGN activity as a function of cosmic time, resulting in better agreement with local observations.

Searching for the influence radius of AGN in nearby narrow emission-line galaxies using the CALIFA survey

NASA Astrophysics Data System (ADS)

Robleto-Orús, A. C.; Torres-Papaqui, J. P.; Coziol, R.; Morales-Vargas, A.; Romero-Cruz, F. J.; Ortega-Minakata, R. A.; Chow-Martinez, M.; Trejo-Alonso, J. J.

2017-07-01

In narrow emission-line galaxies, one important problem consists in discriminating gas ionization due to an AGN and gas ionization due to OB stars in active star-forming regions. This problem becomes more acute in case of AGNs classified as transition-type objects (TO), where star formation is relatively intense, and for LINERs, where the AGN is very weak. Thanks to the integral field spectroscopy, we have a new way to attack this problem. By definition, OB stars ionize a definite portion of space, the Strömgren's sphere, which size depends on the total luminosity of the star, its temperature, and the density of the surrounding gas. Therefore one expects gas ionized by OB stars to cover limited areas in a galaxy. On the other hand, due to the huge amount of ionizing photons emitted by an AGN, its "influence radius" is expected do be much more extended, in the order of kpc. Using a sample of galaxies from included in the CALIFA survey DR3, we will test a new way to measure the characteristic "influence radius" of AGN with different intensities.

Effects of CTLA4-Fc on glomerular injury in humorally-mediated glomerulonephritis in BALB/c mice

PubMed Central

Kitching, A R; Huang, X R; Ruth, A-J; Tipping, P G; Holdsworth, S R

2002-01-01

The effect of cytotoxic T-lymphocyte-associated molecule 4-immunoglobulin fusion protein (CTLA4-Fc) on humorally-mediated glomerulonephritis was studied in accelerated anti-glomerular basement membrane (anti-GBM) glomerulonephritis induced in BALB/c mice. This strain of mice develops antibody and complement dependent glomerulonephritis under this protocol. Sensitized BALB/c mice developed high levels of circulating autologous antibody titres, intense glomerular deposition of mouse immunoglobulin and complement, significant proteinuria, renal impairment, significant glomerular necrosis and a minor component of crescent formation 10 days after challenge with a nephritogenic antigen (sheep anti-GBM globulin). Early treatment during the primary immune response, or continuous treatment throughout the disease with CTLA4-Fc, significantly suppressed mouse anti-sheep globulin antibody titres in serum, and immunoglobulin and complement deposition in glomeruli. The degree of glomerular necrosis was improved and proteinuria was reduced, particularly in the earlier stages of disease. Late treatment by CTLA4-Fc starting one day after challenge with sheep anti-mouse GBM did not affect antibody production and did not attenuate glomerulonephritis. The low level of crescent formation found in BALB/c mice developing glomerulonephritis was not prevented by the administration of CTLA4-Fc. These results demonstrate that CTLA4-Fc is of benefit in this model of glomerulonephritis by its capacity to attenuate antibody production, without affecting the minor degree of cell-mediated glomerular injury. PMID:12067297

Effects of CTLA4-Fc on glomerular injury in humorally-mediated glomerulonephritis in BALB/c mice.

PubMed

Kitching, A R; Huang, X R; Ruth, A-J; Tipping, P G; Holdsworth, S R

2002-06-01

The effect of cytotoxic T-lymphocyte-associated molecule 4-immunoglobulin fusion protein (CTLA4-Fc) on humorally-mediated glomerulonephritis was studied in accelerated anti-glomerular basement membrane (anti-GBM) glomerulonephritis induced in BALB/c mice. This strain of mice develops antibody and complement dependent glomerulonephritis under this protocol. Sensitized BALB/c mice developed high levels of circulating autologous antibody titres, intense glomerular deposition of mouse immunoglobulin and complement, significant proteinuria, renal impairment, significant glomerular necrosis and a minor component of crescent formation 10 days after challenge with a nephritogenic antigen (sheep anti-GBM globulin). Early treatment during the primary immune response, or continuous treatment throughout the disease with CTLA4-Fc, significantly suppressed mouse anti-sheep globulin antibody titres in serum, and immunoglobulin and complement deposition in glomeruli. The degree of glomerular necrosis was improved and proteinuria was reduced, particularly in the earlier stages of disease. Late treatment by CTLA4-Fc starting one day after challenge with sheep anti-mouse GBM did not affect antibody production and did not attenuate glomerulonephritis. The low level of crescent formation found in BALB/c mice developing glomerulonephritis was not prevented by the administration of CTLA4-Fc. These results demonstrate that CTLA4-Fc is of benefit in this model of glomerulonephritis by its capacity to attenuate antibody production, without affecting the minor degree of cell-mediated glomerular injury.

Observational Signatures Of Agn Feedback Across Cosmic Time

NASA Astrophysics Data System (ADS)

Wylezalek, Dominika

2017-06-01

While many compelling models of AGN feedback exist, there is no clear data-driven picture of how winds are launched, how they propagate through the galaxy and what impact they have on the galactic gas. Recent work suggests that AGN luminosity plays an important role. The following described projects focus on understanding the power, reach and impact of feedback processes exerted by AGN of different power. I first describe recent efforts in our group of relating feedback signatures in powerful quasars to the specific star formation rate in their host galaxies, where our results are consistent with the AGN having a `negative' impact through feedback on the galaxies' star formation history. Feedback signatures seem to be best observable in gas-rich galaxies where the coupling of the AGN-driven wind to the gas is strongest, in agreement with recent simulations. But how and where does this quenching happen? Is it accomplished through the mechanical action of jets or through nuclear winds driven by radiation pressure? Finally, I show that AGN signatures and AGN-driven winds can be easily hidden and not be apparent in the integrated spectrum of a galaxy hosting a low/intermediate-luminosity AGN. Using data from the new SDSS-IV MaNGA survey, we have developed a new AGN selection algorithm tailored to IFU data and we are uncovering a much more nuanced picture of AGN activity allowing us to discover AGN signatures at large distances from the galaxy center. This implies that large IFU surveys, such as the SDSS-IV MaNGA survey, might uncover many previously unknown AGN and feedback signatures related to them. Outflows and feedback from low- and intermediate-luminosity AGN might have been underestimated in the past but can potentially significantly contribute to the AGN/host-galaxy self-regulation.

Anti–LAMP-2 Antibodies Are Not Prevalent in Patients With Antineutrophil Cytoplasmic Autoantibody Glomerulonephritis

PubMed Central

Brown, Michael C.; Smith, Rex Neal; Badhwar, Anshul K.; Parente, Oscar; Chung, Hyun chul; O’Dell, Donna; Bunch; McGregor, JulieAnne G.; Hogan, Susan L.; Hu, Yichun; Yang, Jia-Jin; Berg, Elisabeth A.; Niles, John; Jennette, J. Charles; Preston, Gloria A.; Falk, Ronald J.

2012-01-01

Lysosomal membrane protein 2 (LAMP-2) is a target of antineutrophil cytoplasmic autoantibodies (ANCA) in addition to the more commonly known targets proteinase 3 and myeloperoxidase. The prevalence of anti–LAMP-2 antibodies and their relationship to disease in ANCA glomerulonephritis are not well described. We measured anti–LAMP-2 reactivity in 680 sera samples (two academic centers) from patients with ANCA glomerulonephritis (n=329); those with ANCA-negative glomerulonephritis (n=104); those with fimbriated, gram-negative Escherichia coli urinary tract infection (n=104); disease controls (n=19); and healthy volunteers (n=124). With levels in healthy controls used to define a reference range, anti–LAMP-2 reactivity was present in 21% of ANCA sera from two of the centers; reactivity was present in 16% of the control group with urinary tract infection. Western blotting and immunofluorescence microscopy did not verify positivity. Titers of anti-myeloperoxidase and anti–proteinase 3 antibodies were 1500-fold and 10,000-fold higher than anti–LAMP-2 titers, respectively. There was no correlation between anti–LAMP-2 antibodies and disease activity. Furthermore, Wistar Kyoto rats injected with anti–LAMP-2 antibodies did not develop glomerulonephritis. In conclusion, antibodies that react with LAMP-2 may exist at very low titers in a minority of patients with ANCA disease. These data do not support a mechanistic relationship between anti–LAMP-2 antibodies and ANCA glomerulonephritis. PMID:22021709

The Swift/BAT AGN Spectroscopic Survey. IX. The Clustering Environments of an Unbiased Sample of Local AGNs

NASA Astrophysics Data System (ADS)

Powell, M. C.; Cappelluti, N.; Urry, C. M.; Koss, M.; Finoguenov, A.; Ricci, C.; Trakhtenbrot, B.; Allevato, V.; Ajello, M.; Oh, K.; Schawinski, K.; Secrest, N.

2018-05-01

We characterize the environments of local accreting supermassive black holes by measuring the clustering of AGNs in the Swift/BAT Spectroscopic Survey (BASS). With 548 AGN in the redshift range 0.01 < z < 0.1 over the full sky from the DR1 catalog, BASS provides the largest, least biased sample of local AGNs to date due to its hard X-ray selection (14–195 keV) and rich multiwavelength/ancillary data. By measuring the projected cross-correlation function between the AGN and 2MASS galaxies, and interpreting it via halo occupation distribution and subhalo-based models, we constrain the occupation statistics of the full sample, as well as in bins of absorbing column density and black hole mass. We find that AGNs tend to reside in galaxy group environments, in agreement with previous studies of AGNs throughout a large range of luminosity and redshift, and that on average they occupy their dark matter halos similar to inactive galaxies of comparable stellar mass. We also find evidence that obscured AGNs tend to reside in denser environments than unobscured AGNs, even when samples were matched in luminosity, redshift, stellar mass, and Eddington ratio. We show that this can be explained either by significantly different halo occupation distributions or statistically different host halo assembly histories. Lastly, we see that massive black holes are slightly more likely to reside in central galaxies than black holes of smaller mass.

BAT AGN Spectroscopic Survey. V. X-Ray Properties of the Swift/BAT 70-month AGN Catalog

NASA Astrophysics Data System (ADS)

Ricci, C.; Trakhtenbrot, B.; Koss, M. J.; Ueda, Y.; Del Vecchio, I.; Treister, E.; Schawinski, K.; Paltani, S.; Oh, K.; Lamperti, I.; Berney, S.; Gandhi, P.; Ichikawa, K.; Bauer, F. E.; Ho, L. C.; Asmus, D.; Beckmann, V.; Soldi, S.; Baloković, M.; Gehrels, N.; Markwardt, C. B.

2017-12-01

Hard X-ray (≥10 keV) observations of active galactic nuclei (AGNs) can shed light on some of the most obscured episodes of accretion onto supermassive black holes. The 70-month Swift/BAT all-sky survey, which probes the 14-195 keV energy range, has currently detected 838 AGNs. We report here on the broadband X-ray (0.3-150 keV) characteristics of these AGNs, obtained by combining XMM-Newton, Swift/XRT, ASCA, Chandra, and Suzaku observations in the soft X-ray band (≤slant 10 keV) with 70-month averaged Swift/BAT data. The nonblazar AGNs of our sample are almost equally divided into unobscured ({N}{{H}}< {10}22 {{cm}}-2) and obscured ({N}{{H}}≥slant {10}22 {{cm}}-2) AGNs, and their Swift/BAT continuum is systematically steeper than the 0.3-10 keV emission, which suggests that the presence of a high-energy cutoff is almost ubiquitous. We discuss the main X-ray spectral parameters obtained, such as the photon index, the reflection parameter, the energy of the cutoff, neutral and ionized absorbers, and the soft excess for both obscured and unobscured AGNs.

[Acute inflammatory polyradiculoneuropathy and membranous glomerulonephritis following Epbstein-Barr virus primary infection in a 12-year-old girl].

PubMed

Meyer, P; Soëte, S; Raynaud, P; Henry, V; Morin, D; Rodière, M; Rivier, F; Roubertie, A

2010-11-01

Acute inflammatory polyradiculoneuropathy, or Guillain-Barré syndrome (GBS), is characterized by peripheral nerve demyelination, which leads to rapidly progressive weakness, loss of sensation, and loss of deep tendon reflexes. It is a prototype of postinfectious autoimmune disease, whose pathophysiology is well described in the forms provoked by certain bacteria (molecular mimicry with Campylobacter jejuni), but remains unclear for the forms related to other organisms (cytomegalovirus, Epstein-Barr virus and other herpes group viruses, Mycoplasma pneumoniae). Glomerular lesions can be associated with the neurological symptoms and have also been described after various infections, independently of any signs of polyradiculoneuropathy. We report the observation of a 12-year-old girl who presented with Guillain-Barré syndrome with facial diplegia, ataxia, and intracranial hypertension following Epstein-Barr virus (EBV) primary infection. During the course of the neurological disease, membranous glomerulonephritis (MGN) was diagnosed. The neurological impairment was regressive within 6 months after intravenous immunoglobulin treatment followed by intravenous then oral corticosteroid administration. Viremia remained high more than 6 months after the onset of symptoms. Glomerulopathy progressed independently and finally required immunosuppressant medication with cyclosporine. EBV might be the factor that triggered the autoimmune disorders, as previously reported for systemic lupus erythematosus and multiple sclerosis in children. To the best of our knowledge, this association of 3 conditions (GBS, MGN, and EBV primary infection) has never been reported in the literature. Copyright © 2010 Elsevier Masson SAS. All rights reserved.

The many routes to AGN feedback

NASA Astrophysics Data System (ADS)

Morganti, Raffaella

2017-11-01

The energy released by Active Galactic Nuclei (AGN) in the form of radiation, winds or radio plasma jets, is known to impact on the surrounding interstellar medium. The result of these processes, known as AGN (negative) feedback, is suggested to prevent gas, in and around galaxies, from cooling, and to remove, or at least redistribute, gas by driving massive and fast outflows, hence playing a key role in galaxy evolution. Given its importance, a large effort is devoted by the astronomical community to trace the effects of AGN on the surrounding gaseous medium and to quantify their impact for different types of AGN. This review briefly summarizes some of the recent observational results obtained in different wavebands, tracing different phases of the gas. I also summarise new insights they have brought, and the constraints they provide to numerical simulations of galaxy formation and evolution. The recent addition of deep observations of cold gas and, in particular, of cold molecular gas, has brought some interesting surprises and has expanded our understanding of AGN and AGN feedback.

Studying AGN Activation in Galaxy Mergers

NASA Astrophysics Data System (ADS)

Negus, James; Blecha, Laura

2018-06-01

Simulations predict that galaxy mergers drive central gas inflows that result in a peak AGN fraction when the two galaxy bulges reach separations near 1 kpc. Moreover, observations have shown that the AGN fraction increases as the separation between two merging galaxies decreases from 100 kpc to 10 kpc; however, the trend has not yet been measured in the pivotal sub 10 kpc regime, where activity may drastically increase as the simulations suggest. We present a uniform sample of dual and offset AGN, which features AGN parameters (e.g., redshift, angular separation) and normalized cosmology-dependent parameters (e.g., physical separation, bolometric luminosity), using multi-wavelength observations (IR to X-ray) in this critical sub 10 kpc range. In addition, using galaxy merger simulations with GADGET-3, a smoothed particle hydrodynamics N-body code, we report how much time galaxy pairs spend at different separations during a merger. Using these results, we will discuss how galaxy bulge separation correlates to increases in the AGN fraction over varying timescales, and where AGN are primarily fueled during mergers with galaxy bulge separations < 10 kpc.

Immunoadsorption in Anti-GBM Glomerulonephritis: Case Report in a Child and Literature Review.

PubMed

Dorval, Guillaume; Lion, Mathilde; Guérin, Sophie; Krid, Saoussen; Galmiche-Rolland, Louise; Salomon, Rémi; Boyer, Olivia

2017-11-01

Antiglomerular basement membrane glomerulonephritis (anti-GBM GN) is a rare autoimmune disease that is characterized by rapidly progressive glomerulonephritis that may be associated with pulmonary hemorrhage. Anti-GBM GN is caused by autoantibodies (classically type G immunoglobulin) directed against the α3 subunit of type IV collagen. Without any appropriate treatment, the disease is generally fulminant, and patient and kidney survival is poor. The current guidelines recommend the use of plasma exchanges and immunosuppressive drugs. Immunoadsorption (IA) can remove pathogenic IgGs from the circulation and do not require plasma infusions, contrary to plasma exchanges. IA has seldom been used in adult patients with good tolerance and efficiency. We report herein the first pediatric case successfully treated with IA combined with immunosuppressive drugs in a 7-year-old girl who presented acute kidney injury (estimated glomerular filtration rate 38 mL/minute/1.73 m 2 ). A kidney biopsy revealed numerous >80% glomerular crescents and linear IgG deposits along the glomerular basement membrane. Ten IA sessions led to rapid and sustained clearance of autoantibodies and improvement of kidney function until 21 months after onset (glomerular filtration rate 87 mL/minute/1.73 m 2 ). No adverse effect was noted. This report adds to the growing body of evidence suggesting IA as a therapeutic alternative to plasma exchanges in anti-GBM GN. The other 27 published pediatric cases of anti-GBM GN are reviewed. Copyright © 2017 by the American Academy of Pediatrics.

The Lick AGN Monitoring Project 2016: Extending Reverberation Mapping to Higher Luminosity AGNs

NASA Astrophysics Data System (ADS)

U, Vivian; LAMP2016 Collaboration

2017-01-01

The technique of reverberation mapping has been used to estimate virial black hole masses and, more fundamentally, to probe the broad line region structure in Seyfert I galaxies. Efforts from the previous Lick AGN Monitoring Project (LAMP) campaigns and other studies to date have culminated in a large sample of reverberation mapped AGNs and measurements of their black hole masses, which in turn enabled major improvement to various AGN scaling relations. However, the high-luminosity end of such relations remains poorly constrained; this is because of observational challenges presented by the weaker continuum flux variations and longer time dilation in these sources. To this end, we have initiated a new LAMP2016 campaign to target AGNs with luminosities of 10^44 erg/s, with predicted H-beta lags of ~20 - 60 days or black hole masses of 10^7 - 10^8.5 Msun. Designed to monitor ~20 AGNs biweekly from Spring 2016 through Winter 2017 with the Kast spectrograph on the 3-m Shane Telescope at Lick Observatory, we aim to probe luminosity-dependent trends in broad line region structure and dynamics, improve calibrations for single-epoch estimates of high-redshift quasar black hole masses, and test photoionization models for the radially-stratified structure of the broad line region. In this talk, I will present the overview and scope of LAMP2016 and show preliminary results from our ongoing campaign.

The environmental properties of radio-emitting AGN

NASA Astrophysics Data System (ADS)

Magliocchetti, M.; Popesso, P.; Brusa, M.; Salvato, M.

2018-05-01

We study the environmental properties of z≲ 1.2 radio-selected AGN belonging to the ˜2 deg2 of the COSMOS field, finding that about 20% of them appear within overdense structures. AGN with P_{1.4 GHz}>10^{23.5} W Hz^{-1} sr^{-1} are twice more likely to be found in clusters with respect to fainter sources (˜38% vs ˜15%), just as radio-selected AGN with stellar masses M* > 1011M⊙ are twice more likely to be found in overdense environments with respect to objects of lower mass (˜24% vs ˜11%). Comparisons with galaxy samples further suggest that radio-selected AGN of large stellar mass tend to avoid underdense environments more than normal galaxies with the same stellar content. Stellar masses also seem to determine the location of radio-active AGN within clusters: ˜100% of the sources found as satellite galaxies have M* < 1011.3M⊙, while ˜100% of the AGN coinciding with a cluster central galaxy have M* > 1011M⊙. No different location within the cluster is instead observed for AGN of various radio luminosities. Radio AGN which also emit in the MIR show a marked preference to be found as isolated galaxies (˜70%) at variance with those also active in the X-ray which all seem to reside within overdensities. What emerges from our work is a scenario whereby physical processes on sub-pc and kpc scales (e.g. emission respectively related to the AGN and to star formation) are strongly interconnected with the large-scale environment of the AGN itself.

Coexistence of Anti-Glomerular Basement Membrane Glomerulonephritis and Membranous Nephropathy in a Female Patient with Preserved Renal Function.

PubMed

Ogawara, Aoi; Harada, Makoto; Ichikawa, Tohru; Fujii, Kazuaki; Ehara, Takashi; Kobayashi, Mamoru

2017-12-01

Renal prognosis for anti-glomerular basement membrane (GBM) glomerulonephritis is poor. The greater the amount of anti-GBM antibody binding the antigen (type IV collagen of the glomerular basement membrane), the greater the number of crescents that develop in glomeruli, resulting in progression of renal impairment. Immunofluorescence staining reveals linear IgG depositions on glomerular capillary walls. Membranous nephropathy (MN) is one of the most common causes of nephrotic syndrome in middle-aged to elderly patients. Immune complex is deposited in the sub-epithelial space of the glomerulus resulting in the development of a membranous lesion. Immunofluorescence staining reveals granular IgG depositions on glomerular capillary walls. Coexisting anti-GBM glomerulonephritis and MN are rare and, here we report a case of coexisting anti-GBM glomerulonephritis and MN with preserved renal function. There are some cases of coexisting anti-GBM glomerulonephritis and MN do not show severely decreased renal function. A 76-year-old Japanese woman presented with nephrotic syndrome, microscopic hematuria, and was positive for anti-GBM antibody. Kidney biopsy revealed linear and granular IgG depositions in glomerular capillary walls, crescent formations, and electron-dense deposits in the sub-epithelial space. She was diagnosed with anti-GBM glomerulonephritis and MN. Steroid and cyclosporine therapy achieved complete remission, and kidney function was preserved. In conclusion, coexisting anti-GBM glomerulonephritis and MN can have preserved renal function. IgG subclass of deposited anti-GBM antibody may be associated with the severity of anti-GBM glomerulonephritis. In addition, in the case of nephrotic syndrome with hematuria, we should consider the possibility of coexisting anti-GBM glomerulonephritis and MN.

Deep ALMA photometry of distant X-ray AGN: improvements in star formation rate constraints, and AGN identification

NASA Astrophysics Data System (ADS)

Stanley, F.; Harrison, C. M.; Alexander, D. M.; Simpson, J.; Knudsen, K. K.; Mullaney, J. R.; Rosario, D. J.; Scholtz, J.

2018-05-01

We present the star formation rates (SFRs) of a sample of 109 galaxies with X-ray selected active galactic nuclei (AGN) with moderate to high X-ray luminosities (\\mathrel {L_2-8{keV}}= 10^{42} - 10^{45} \\mathrel {erg {} s^{-1}}), at redshifts 1 < z < 4.7, that were selected to be faint or undetected in the Herschel bands. We combine our deep ALMA continuum observations with deblended 8-500\\mathrel {μ m} photometry from Spitzer and Herschel, and use infrared (IR) SED fitting and AGN - star formation decomposition methods. The addition of the ALMA photometry results in an order of magnitude more X-ray AGN in our sample with a measured SFR (now 37 per cent). The remaining 63 per cent of the sources have SFR upper limits that are typically a factor of 2-10 times lower than the pre-ALMA constraints. With the improved constraints on the IR SEDs, we can now identify a mid-IR (MIR) AGN component in 50 per cent of our sample, compared to only ˜1 per cent previously. We further explore the F_{870\\mathrel {μ m}}/F_{24\\mathrel {μ m}}-redshift plane as a tool for the identification of MIR emitting AGN, for three different samples representing AGN dominated, star formation dominated, and composite sources. We demonstrate that the F_{870\\mathrel {μ m}}/F_{24\\mathrel {μ m}}-redshift plane can successfully split between AGN and star formation dominated sources, and can be used as an AGN identification method.

AGN UNIFICATION AT z {approx} 1: u - R COLORS AND GRADIENTS IN X-RAY AGN HOSTS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mark Ammons, S.; Rosario, David J. V.; Koo, David C., E-mail: ammons@as.arizona.edu, E-mail: rosario@ucolick.org, E-mail: koo@ucolick.org

2011-10-10

We present uncontaminated rest-frame u - R colors of 78 X-ray-selected active galactic nucleus (AGN) hosts at 0.5 < z < 1.5 in the Chandra Deep Fields measured with Hubble Space Telescope (HST)/Advanced Camera for Surveys/NICMOS and Very Large Telescope/ISAAC imaging. We also present spatially resolved NUV - R color gradients for a subsample of AGN hosts imaged by HST/Wide Field Camera 3 (WFC3). Integrated, uncorrected photometry is not reliable for comparing the mean properties of soft and hard AGN host galaxies at z {approx} 1 due to color contamination from point-source AGN emission. We use a cloning simulation tomore » develop a calibration between concentration and this color contamination and use this to correct host galaxy colors. The mean u - R color of the unobscured/soft hosts beyond {approx}6 kpc is statistically equivalent to that of the obscured/hard hosts (the soft sources are 0.09 {+-} 0.16 mag bluer). Furthermore, the rest-frame V - J colors of the obscured and unobscured hosts beyond {approx}6 kpc are statistically equivalent, suggesting that the two populations have similar distributions of dust extinction. For the WFC3/infrared sample, the mean NUV - R color gradients of unobscured and obscured sources differ by less than {approx}0.5 mag for r > 1.1 kpc. These three observations imply that AGN obscuration is uncorrelated with the star formation rate beyond {approx}1 kpc. These observations favor a unification scenario for intermediate-luminosity AGNs in which obscuration is determined geometrically. Scenarios in which the majority of intermediate-luminosity AGNs at z {approx} 1 are undergoing rapid, galaxy-wide quenching due to AGN-driven feedback processes are disfavored.« less

The Keck OSIRIS Nearby AGN (KONA) Survey: AGN Fueling and Feedback

NASA Astrophysics Data System (ADS)

Hicks, Erin K. S.; Müller-Sánchez, Francisco; Malkan, Matthew A.; Yu, Po-Chieh

In an effort to better constrain the relevant physical processes dictating the co-evolution of supermassive black holes and the galaxies in which they reside we turn to local Seyfert AGN. It is only with these local AGN that we can reach the spatial resolution needed to adequately characterize the inflow and outflow mechanisms thought to be the driving forces in establishing the relationship between black holes and their host galaxies at higher redshift. We present the first results from the KONA (Keck OSIRIS Nearby AGN) survey, which takes advantage of the integral field unit OSIRIS plus laser and natural guide star adaptive optics to probe down to scales of 5-30 parsecs in a sample of 40 local Seyfert galaxies. With these K-band data we measure the two-dimensional distribution and kinematics of the nuclear stars, molecular gas, and ionized gas within the central few hundred parsecs.

Compton Thick AGN in the COSMOS field

NASA Astrophysics Data System (ADS)

Lanzuisi, Giorgio; Cosmos Collaboration

2015-09-01

I will present the results we published in a couple of recent papers (Lanzuisi et al. 2015, A&A 573A 137, Lanzuisi et al. 2015, arXiv 1505.01153) on the properties of X-ray selected Compton Thick (CT, NH>10^24 cm^-2) AGN, in the COSMOS survey. We exploited the rich multi-wavelength dataset available in this field, to show that CT AGN tend to harbor smaller, rapidly growing SMBH with respect to unobscured AGN, and have a higher chance of being hosted by star-forming, merging and post-merger systems.We also demonstrated the detectability of even more heavily obscured AGN (NH>10^25 cm^-2), thanks to a truly multi-wavelength approach in the same field. The extreme source detected in this way shows strong evidences of ongoing powerful AGN feedback, detected as blue-shifted wings of high ionization optical emission lines such as [NeV] and [FeVII], as well as of the [OIII] emission line.The results obtained from these works point toward a scenario in which highly obscured AGN occupy a peculiar place in the galaxy-AGN co-evolution process, in which both the host and the SMBH rapidly evolve toward the local relations.We will also present estimates on the detectability of such extreme sources up to redshift ~6-7 with Athena. Combining the most up to date models for the Luminosity Function of CT AGN at high z, aggressive data analysis techniques on faint sources, and the current Athena survey design, we demonstrate that we will detect, and recognize as such, a small (few to ten) but incredibly valuable sample of CT AGN at such high redshift.

The SWIFT AGN and Cluster Survey. I. Number Counts of AGNs and Galaxy Clusters

NASA Astrophysics Data System (ADS)

Dai, Xinyu; Griffin, Rhiannon D.; Kochanek, Christopher S.; Nugent, Jenna M.; Bregman, Joel N.

2015-05-01

The Swift active galactic nucleus (AGN) and Cluster Survey (SACS) uses 125 deg2 of Swift X-ray Telescope serendipitous fields with variable depths surrounding γ-ray bursts to provide a medium depth (4× {{10}-15} erg cm-2 s-1) and area survey filling the gap between deep, narrow Chandra/XMM-Newton surveys and wide, shallow ROSAT surveys. Here, we present a catalog of 22,563 point sources and 442 extended sources and examine the number counts of the AGN and galaxy cluster populations. SACS provides excellent constraints on the AGN number counts at the bright end with negligible uncertainties due to cosmic variance, and these constraints are consistent with previous measurements. We use Wide-field Infrared Survey Explorer mid-infrared (MIR) colors to classify the sources. For AGNs we can roughly separate the point sources into MIR-red and MIR-blue AGNs, finding roughly equal numbers of each type in the soft X-ray band (0.5-2 keV), but fewer MIR-blue sources in the hard X-ray band (2-8 keV). The cluster number counts, with 5% uncertainties from cosmic variance, are also consistent with previous surveys but span a much larger continuous flux range. Deep optical or IR follow-up observations of this cluster sample will significantly increase the number of higher-redshift (z\\gt 0.5) X-ray-selected clusters.

Enhancement of AGN Activity in Distant Galaxy Clusters

NASA Astrophysics Data System (ADS)

Krishnan, Charutha; Hatch, Nina; Almaini, Omar

2017-07-01

I present our recent study of the prevalence of X-ray AGN in the high-redshift protocluster Cl 0218.3-0510 at z=1.62, and review the implications for our understanding of galaxy evolution. There has long been a consensus that X-ray AGN avoid clusters in the local universe, particularly their cores. The high-redshift universe appears to not follow these trends, as there is a reversal in the local anti-correlation between galaxy density and AGN activity. In this z=1.62 protocluster, we find a large overdensity of AGN by a factor of 23, and an enhancement in the AGN fraction among massive galaxies relative to the field by a factor of 2. I will discuss the comparison of the properties of AGN in the protocluster to the field, and explain how our results point towards similar triggering mechanisms in the two environments. I will also describe how our study of the morphologies of these galaxies provide tentative evidence towards galaxy mergers and interactions being responsible for triggering AGN, and explain the reversal of the local anti-correlation between galaxy density and AGN activity.

The AGN-Star Formation Connection: Future Prospects with JWST

NASA Astrophysics Data System (ADS)

Kirkpatrick, Allison; Alberts, Stacey; Pope, Alexandra; Barro, Guillermo; Bonato, Matteo; Kocevski, Dale D.; Pérez-González, Pablo; Rieke, George H.; Rodríguez-Muñoz, Lucia; Sajina, Anna; Grogin, Norman A.; Mantha, Kameswara Bharadwaj; Pandya, Viraj; Pforr, Janine; Salvato, Mara; Santini, Paola

2017-11-01

The bulk of the stellar growth over cosmic time is dominated by IR-luminous galaxies at cosmic noon (z=1{--}2), many of which harbor a hidden active galactic nucleus (AGN). We use state-of-the-art infrared color diagnostics, combining Spitzer and Herschel observations, to separate dust-obscured AGNs from dusty star-forming galaxies (SFGs) in the CANDELS and COSMOS surveys. We calculate 24 μm counts of SFGs, AGN/star-forming “Composites,” and AGNs. AGNs and Composites dominate the counts above 0.8 mJy at 24 μm, and Composites form at least 25% of an IR sample even to faint detection limits. We develop methods to use the Mid-Infrared Instrument (MIRI) on JWST to identify dust-obscured AGNs and Composite galaxies from z˜ 1{--}2. With the sensitivity and spacing of MIRI filters, we will detect >4 times as many AGN hosts as with Spitzer/IRAC criteria. Any star formation rates based on the 7.7 μm PAH feature (likely to be applied to MIRI photometry) must be corrected for the contribution of the AGN, or the star formation rate will be overestimated by ˜35% for cases where the AGN provides half the IR luminosity and ˜50% when the AGN accounts for 90% of the luminosity. Finally, we demonstrate that our MIRI color technique can select AGNs with an Eddington ratio of {λ }{Edd}˜ 0.01 and will identify AGN hosts with a higher specific star formation rate than X-ray techniques alone. JWST/MIRI will enable critical steps forward in identifying and understanding dust-obscured AGNs and the link to their host galaxies.

Examining an AGN Luminosity – SFR relation

NASA Astrophysics Data System (ADS)

Stemo, Aaron; Comerford, Julia M.; Barrows, Robert Scott

2018-06-01

The relation between the star formation rate (SFR) of a galaxy and the accretion rate of its supermassive black hole is not well understood. Some observations show that active galactic nuclei (AGN) activity and SFR are correlated while other observations show no relation between the two. In this work we present a large, uniformly-selected catalog of HST galaxies that host AGN. Using available multiwavelength photometric data, we are able to determine AGN bolometric luminosity, host galaxy SFR, host galaxy stellar mass, and redshift for our sample. Using this catalog, we are able to compare AGN bolometric luminosity and SFR, while controlling for redshift and stellar mass. These comparisons will be used to make a statistically significant statement on the correlation between AGN activity and a host galaxy’s SFR.

The spectrum of glomerulonephritis in saudi arabia: the results of the saudi registry.

PubMed

Huraib, S; Al Khader, A; Shaheen, F A; Abu Aisha, H; Souqiyyeh, M Z; Al Mohana, F; Soliman, M; Al Wakeel, J; Mitwalli, A; Al Mohaya, S; Said, R; Al Menawy, L; Sohaibani, M; Chan, N

2000-01-01

Only few studies regarding glomerulonephritis, with relatively small numbers of patients, have so far been published from different centers in Saudi Arabia, and have reported conflicting results regarding the patterns, even in the same city. The possible reasons for these differences include the small number of patients in the different studies, differences in the indications for renal biopsies, referral bias, geographical differences, and, sometimes, the non-availability of the necessary diagnostic facilities in the reporting centers. In order to overcome these problems, a registry for glomerulonephropathy was attempted in Saudi Arabia. Six large referral hospitals from different regions of Saudi Arabia participated in this registry. Biopsy reports and clinical information of 1294 renal biopsies were obtained. There were 782 renal biopsies due to glomerulonephritis (GN) accounting for 77.2% of the total biopsies. Five hundred eighty seven (72.6%) were primary glomerulonephritidis. Focal and segmental glomerulosclerosis (FSGS) (21.3%) and membrano-proliferative glomerulonephritis (MPGN) (20.7%) were the most common types found in the primary glomerulonephritidis. Membranous glomerulonephritis (MGN) was present in only 10.6% of the cases. IgA nephropathy was found in 6.5% of the cases. Of the secondary glomerulo-nephritides, systemic lupus erythematosus (SLE) was the most common indication for biopsy (57.0%) and amyloidosis was found in only 3.2% of the biopsies. In conclusion, FSGS and MPGN were the most common forms of primary glomerulonephritis in adult patients in Saudi Arabia. MGN was not as common as in the western world. SLE was the commonest cause of secondary GN. Amyloidosis was not as common as in other Arab countries. There is a need for more centers from Saudi Arabia to join this national GN registry. Similar registries can be established in different Arab countries, which all would, hopefully, lead to a Pan-Arab GN registry.

Central venous catheter infection-related glomerulonephritis under long-term parenteral nutrition: a report of two cases.

PubMed

Okada, Mari; Sato, Mai; Ogura, Masao; Kamei, Koichi; Matsuoka, Kentaro; Ito, Shuichi

2016-03-31

Advances in long-term parenteral nutrition via indwelling central venous catheter have improved the quality of life and mortality in patients with life-threatening gastrointestinal diseases complicated with severely impaired absorption. However, infection to central venous catheter is still a common and critical complication for such patients. We encountered two patients under long-term parenteral nutrition who developed glomerulonephritis associated with central venous catheter infection. Persistent bacterial infection in indwelling medical devices placed in the blood-stream such as a ventricular-atrial shunt is known to cause glomerulonephritis, a condition termed shunt nephritis. We reported the clinical manifestations, treatment and their pathological findings in the two patients with glomerulonephritis associated with central venous catheter infection. Both patients suffered from megacystis microcolon intestinal hypoperistalsis syndrome, a form of pseudo-Hirschsprung's disease. They had been receiving home parenteral nutrition via central venous catheter because of severe malabsorption. They presented proteinuria, hematuria, hypocomplementemia and positive PR3-antineutrophilic cytoplasmic antibody accompanied by Staphylococcus epidermidis infection in the central venous catheter. Their renal biopsy revealed membranoproliferative glomerulonephritis with positive C3 deposition. One of them recovered completely following the removal of catheter and administration of antibiotics, while another did not respond to the treatments. We then treated her with methylprednisolone pulse therapy followed by prednisolone. She responded well, and achieved complete remission. As central venous catheter infection-related glomerulonephritis has a similar etiology to shunt nephritis, removal of the catheter and administration of antibiotics is fundamental to the treatment. If a patient is resistant to such conventional therapy, additional steroid and/or immunosuppressive agent

Mini Survey of SDSS [OIII] AGN with Swift: Testing the Hypothesis that L(sub [OIII]) Traces AGN Luminosity

NASA Technical Reports Server (NTRS)

2007-01-01

The number of AGN and their luminosity distribution are crucial parameters for our understanding of the AGN phenomenon. Recent work strongly suggests every massive galaxy has a central black hole. However most of these objects either are not radiating or have been very difficult to detect We are now in the era of large surveys, and the luminosity function (LF] of AGN has been estimated in various ways. In the X-ray band. Chandra and XMM surveys have revealed that the LF of hard X-ray selected AGN shows a strong luminosity-dependent evolution with a dramatic break towards low L(sub x) (at all z). This is seen for all types of AGN, but is stronger for the broad-line objects. In sharp contrast, the local LF of optically-selected samples shows no such break and no differences between narrow and broad-line objects. If as been suggested, hard X ray and optical emission line can both can be fair indicators of AGN activity, it is important to first understand how reliable these characteristics are if we hope to understand the apparent discrepancy in the LFs.

AGN outflows as neutrino sources: an observational test

NASA Astrophysics Data System (ADS)

Padovani, P.; Turcati, A.; Resconi, E.

2018-04-01

We test the recently proposed idea that outflows associated with Active Galactic Nuclei (AGN) could be neutrino emitters in two complementary ways. First, we cross-correlate a list of 94 "bona fide" AGN outflows with the most complete and updated repository of IceCube neutrinos currently publicly available, assembled by us for this purpose. It turns out that AGN with outflows matched to an IceCube neutrino have outflow and kinetic energy rates, and bolometric powers larger than those of AGN with outflows not matched to neutrinos. Second, we carry out a statistical analysis on a catalogue of [O III] λ5007 line profiles using a sample of 23,264 AGN at z < 0.4, a sub-sample of which includes mostly possible outflows sources. We find no significant evidence of an association between the AGN and the IceCube events, although we get the smallest p-values (˜6 and 18 per cent respectively, pre-trial) for relatively high velocities and luminosities. Our results are consistent with a scenario where AGN outflows are neutrino emitters but at present do not provide a significant signal. This can be tested with better statistics and source stacking. A predominant role of AGN outflows in explaining the IceCube data appears in any case to be ruled out.

AGN outflows as neutrino sources: an observational test

NASA Astrophysics Data System (ADS)

Padovani, P.; Turcati, A.; Resconi, E.

2018-07-01

We test the recently proposed idea that outflows associated with Active Galactic Nuclei (AGN) could be neutrino emitters in two complementary ways. First, we cross-correlate a list of 94 'bona fide' AGN outflows with the most complete and updated repository of IceCube neutrinos currently publicly available, assembled by us for this purpose. It turns out that AGN with outflows matched to an IceCube neutrino have outflow and kinetic energy rates, and bolometric powers larger than those of AGN with outflows not matched to neutrinos. Secondly, we carry out a statistical analysis on a catalogue of [O III] λ5007 line profiles using a sample of 23 264 AGN at z < 0.4, a subsample of which includes mostly possible outflow sources. We find no significant evidence of an association between the AGN and the IceCube events, although we get the smallest p-values (˜6 and 18 per cent, respectively, pre-trial) for relatively high velocities and luminosities. Our results are consistent with a scenario where AGN outflows are neutrino emitters but at present do not provide a significant signal. This can be tested with better statistics and source stacking. A predominant role of AGN outflows in explaining the IceCube data appears in any case to be ruled out.

AGN Science with AGIS

NASA Astrophysics Data System (ADS)

Coppi, Paolo

2009-05-01

AGIS, a proposed future gamma-ray telescope consisting of a square km array of 50 atmospheric Cherenkov telescopes, will provide a powerful new view of the high energy universe. The combination of its increased sensitivity (a factor 10 over current observatories), increased survey capabilities, and a low energy threshold (<30 GeV) that allows observations at energies not subject to absorption on extragalactic background light will result in a dramatic increase in the number of AGN accessible at high energies. The overall number of ``TeV blazar" AGN, those detected by current ground-based observatories, should increase by a factor 30 or more with a corresponding increase in the number of these that can be monitored at high statistical significance to test emission models rigorously. More excitingly, AGIS may also begin to pick up entirely new classes of AGN such as radio galaxies with X-ray emitting hotspots at large distances from the central engine, providing further insight into the outflows from AGN. The low AGIS threshold energy will also allow significant source overlap with objects detected by the recently launched Fermi gamma-ray space observatory at lower, GeV energies. AGIS will significantly improve on the localization and variability monitoring of the Fermi sources it sees.

Unveiling Obscured AGN with X-ray Spectral Analysis

NASA Astrophysics Data System (ADS)

LaMassa, Stephanie M.; Yaqoob, Tahir; Ptak, Andrew; Jia, Jianjun; Heckman, Timothy M.; Gandhi, Poshak; Urry, C. Megan

2014-06-01

With the recent advent of physically motivated, self-consistent X-ray models, the circumnuclear medium enshrouding AGN can now be investigated in unprecedented detail. We applied these models to 19 SDSS [OIII] 5007 Angstrom selected Type 2 AGN, where 9 are local Seyfert 2 galaxies and 10 are more luminous and distant Type 2 quasars. For the first time in a sample of AGN, we constrained both the line-of-sight and global column densities, finding that over half (11/19) are heavily obscured or Compton-thick (NH > 10^23 cm^-2). Four objects have different global from line-of-sight column densities. When correcting the observed X-ray luminosities for obscuration, the L_x/L_[OIII] ratio for these Type 2 AGN is essentially identical to the Seyfert 1 (i.e., unabsorbed AGN) value, which is consistent with both parameters cleanly probing AGN emission.

The Pearson-Readhead AGN Survey

NASA Astrophysics Data System (ADS)

Lister, M. L.

2009-08-01

The Pearson-Readhead survey of active galactic nuclei (AGN) was the first complete sample to be studied by VLBI, and was the subject of a detailed investigation by the VSOP program. We discuss the scientific findings from this unique survey, and how it has provided robust confirmation of the relativistic beaming model for AGN jets.

Epidermal growth factor receptor inhibition with erlotinib ameliorates anti-Thy 1.1-induced experimental glomerulonephritis.

PubMed

Rintala, Jukka M; Savikko, Johanna; Rintala, Sini E; Palin, Niina; Koskinen, Petri K

2016-06-01

Mesangial proliferative glomerulonephritis is a common glomerular disorder that may lead to end-stage renal disease. Epidermal growth factor (EGF) plays an important role in the regulation of cell growth, proliferation, and differentiation and in the pathology of various renal diseases. Erlotinib is a novel, oral, highly selective tyrosine kinase inhibitor of the EGF receptor. It is clinically used to treat non-small cell lung and pancreatic cancers. Here, we investigated the effect of erlotinib on the progression of mesangioproliferative glomerulonephritis in an experimental model. Mesangial glomerulonephritis was induced with anti-rat Thy-1.1 antibody in male Wistar rats weighing 150-160 g. Rats were treated with erlotinib (10 mg/kg/day p.o.) or vehicle only (polyethylene glycol). Native Wistar rat kidneys were used as histological controls. Serum creatinine levels were measured at day 7. Kidneys were harvested 7 days after antibody administration for histology. Native controls showed no histological signs of glomerular pathology. In the vehicle group, intense glomerular inflammation developed after 7 days and prominent mesangial cell proliferation and glomerular matrix accumulation was seen. Erlotinib was well tolerated and there were no adverse effects during the follow-up period. Erlotinib significantly prevented progression of the glomerular inflammatory response and glomerular mesangial cell proliferation as well as matrix accumulation when compared with the vehicle group. Erlotinib also preserved renal function. These results indicate that erlotinib prevents the early events of experimental mesangial proliferative glomerulonephritis. Therefore, inhibition of the EGF receptor with erlotinib could prevent the progression of glomerulonephritis also in clinical nephrology.

AGN host galaxy mass function in COSMOS. Is AGN feedback responsible for the mass-quenching of galaxies?

NASA Astrophysics Data System (ADS)

Bongiorno, A.; Schulze, A.; Merloni, A.; Zamorani, G.; Ilbert, O.; La Franca, F.; Peng, Y.; Piconcelli, E.; Mainieri, V.; Silverman, J. D.; Brusa, M.; Fiore, F.; Salvato, M.; Scoville, N.

2016-04-01

We investigate the role of supermassive black holes in the global context of galaxy evolution by measuring the host galaxy stellar mass function (HGMF) and the specific accretion rate, that is, λSAR, the distribution function (SARDF), up to z ~ 2.5 with ~1000 X-ray selected AGN from XMM-COSMOS. Using a maximum likelihood approach, we jointly fit the stellar mass function and specific accretion rate distribution function, with the X-ray luminosity function as an additional constraint. Our best-fit model characterizes the SARDF as a double power-law with mass-dependent but redshift-independent break, whose low λSAR slope flattens with increasing redshift while the normalization increases. This implies that for a given stellar mass, higher λSAR objects have a peak in their space density at earlier epoch than the lower λSAR objects, following and mimicking the well-known AGN cosmic downsizing as observed in the AGN luminosity function. The mass function of active galaxies is described by a Schechter function with an almost constant M∗⋆ and a low-mass slope α that flattens with redshift. Compared to the stellar mass function, we find that the HGMF has a similar shape and that up to log (M⋆/M⊙) ~ 11.5, the ratio of AGN host galaxies to star-forming galaxies is basically constant (~10%). Finally, the comparison of the AGN HGMF for different luminosity and specific accretion rate subclasses with a previously published phenomenological model prediction for the "transient" population, which are galaxies in the process of being mass-quenched, reveals that low-luminosity AGN do not appear to be able to contribute significantly to the quenching and that at least at high masses, that is, M⋆ > 1010.7 M⊙, feedback from luminous AGN (log Lbol ≳ 46 [erg/s]) may be responsible for the quenching of star formation in the host galaxy.

AGN jets as pion factories

NASA Astrophysics Data System (ADS)

Mannheim, Karl

There has been a dramatic revolution in gamma-ray astronomy throughout the last few years. Beginning with the discovery made by the spark chamber EGRET on board the Compton Gamma Ray Observatory that AGN with jets are the most powerful quasi-steady gamma-ray sources in the Universe, air-Cerenkov telescopes have soon after succeeded in detecting gamma-rays up to TeV energies. In the last year, it has become clear that these AGN emit photons even up to 10 TeV and more. This is a strong indication for proton acceleration going on in them, since protons owing to their large mass suffer weaker energy losses than electrons and can thus reach higher energies. Nucleons escaping from the AGN jets contribute to the local flux of cosmic rays at highest energies. If AGN produce the diffuse gamma-ray background, they would also be able to produce all the cosmic rays above the ankle in the local spectrum. The majority of AGN resides at large distances, indicated by their cosmological redshifts, and can therefore not be seen through the fog of electron-positron pairs which they produce interacting with diffuse infrared radiation from the era of galaxy formation. To observe the cosmic accelerators at large redshifts, neutrino observations are required. It is important to understand the astrophysical neutrino sources in order to be able to recognize signatures of new physics, e.g. due to decaying or annihilating particles from the early phases of the Universe.

Tracing Supermassive Black Hole Growth with Offset and Dual AGN

NASA Astrophysics Data System (ADS)

Comerford, Julia

The growth of supermassive black holes is tied to the evolution of their host galaxies, but we are still missing a fundamental understanding of how and when supermassive black holes build up their mass. Black hole mass growth can be traced when the black holes are powered as active galactic nuclei (AGN), and AGN activity can be triggered by the stochastic accretion of gas or by gas inflows driven by galaxy mergers. Galaxy merger simulations make a series of predictions about the AGN that are triggered by mergers: (1) major mergers preferentially trigger higher-luminosity AGN, (2) minor mergers more often trigger AGN activity in one supermassive black hole while major mergers more often trigger AGN activity in both black holes in a merger, and (3) black hole mass growth peaks when the black holes approach the center (<10 kpc separations) of the merger-remnant galaxy. Observational tests of these predictions from theory have been limited by the difficulty in defining a clean observational sample of AGN in galaxy mergers and the observational challenge of spatially resolving two AGN with small (<10kpc) separations. Here we present offset and dual AGN as a new observational tool that can be used to address how and when supermassive black hole mass growth occurs. A merger of two galaxies brings two supermassive black holes together, and the two black holes exist at kpc-scale separations for 100 Myr before ultimately merging. While the black holes are at kpc-scale separations, they are known as dual AGN when both of them are fueled as AGN and offset AGN when only one is fueled as an AGN. Since offset and dual AGN only occur in galaxy mergers, by their very definition, they provide a clean observational sample of black hole mass growth in galaxy mergers. The small, kpc-scale separations of offset and dual AGN also enable an observational test of black hole fueling near the centers of merger-remnant galaxies. The full potential of offset and dual AGN for such studies of

BAT AGN Spectroscopic Survey. VIII. Type 1 AGN with Massive Absorbing Columns

NASA Astrophysics Data System (ADS)

Shimizu, T. Taro; Davies, Richard I.; Koss, Michael; Ricci, Claudio; Lamperti, Isabella; Oh, Kyuseok; Schawinski, Kevin; Trakhtenbrot, Benny; Burtscher, Leonard; Genzel, Reinhard; Lin, Ming-yi; Lutz, Dieter; Rosario, David; Sturm, Eckhard; Tacconi, Linda

2018-04-01

We explore the relationship between X-ray absorption and optical obscuration within the BAT AGN Spectroscopic Survey (BASS), which has been collecting and analyzing the optical and X-ray spectra for 641 hard X-ray selected (E > 14 keV) active galactic nuclei (AGNs). We use the deviation from a linear broad Hα-to-X-ray relationship as an estimate of the maximum optical obscuration toward the broad line region (BLR) and compare the A V to the hydrogen column densities ({N}{{H}}) found through systematic modeling of their X-ray spectra. We find that the inferred columns implied by A V toward the BLR are often orders of magnitude less than the columns measured toward the X-ray emitting region, indicating a small-scale origin for the X-ray absorbing gas. After removing 30% of Sy 1.9s that potentially have been misclassified due to outflows, we find that 86% (164/190) of the Type 1 population (Sy 1–1.9) are X-ray unabsorbed as expected based on a single obscuring structure. However, 14% (26/190), of which 70% (18/26) are classified as Sy 1.9, are X-ray absorbed, suggesting that the BLR itself is providing extra obscuration toward the X-ray corona. The fraction of X-ray absorbed Type 1 AGNs remains relatively constant with AGN luminosity and Eddington ratio, indicating a stable BLR covering fraction.

[Determination of homeostatic kidney function in the diagnosis of chronic glomerulonephritis].

PubMed

Ratner, M J

1977-12-01

The latent and hypertonic forms of the course of compensated nephritides more frequently make difficulties concerning the differential diagnosis between a chronic glomerulonephritis and a chronic pyelonephritis. According to the results achieved the determination of the renal processes furthering homoeostasis gives the possibility to demarcate the two diseases. A certain reduction of the creatinine clearance (to less than 90 ml/min) and of the maximum water diuresis (to less than 10.0 per 100 ml glomerular filtrate) is suitable for the latent form of the chronic glomerulonephritis. On the other hand, a reduction of the ammonia secretion (to less than 35 per 100 ml glomerular (filtrate) and of the total H+-ion secretion (to less than 50 per 100 ml glomerular filtrate) in the determination after Alkinton is characteristic for the chronic pyelonephritis. In the hypertensive form of the course of the chronic glomerulonephritis in contrast to the same form in chronic pyelonephritis a reduction of the maximum water diuresis to less than 7.5, of the clearance of the "osmotically free" water to less than 6.0, of the titrable acidity to less than 25 is the result. Here the ammonia quotient transgresses 45%. In chronic pyelonephritis the titrable acidity in considerably increased and the ammonia genesis relatively decreased (to less than 45%).

They Call Me Agnes: A Crow Narrative Based on the Life of Agnes Yellowtail Deernose.

ERIC Educational Resources Information Center

Voget, Fred W.; Mee, Mary K.

This book is about life on the Crow Indian Reservation from around 1910 to the present and is based on the personal experiences of Donnie and Agnes Deernose. Following Donnie's death, Agnes became the principal narrator of the book. The Crow Indian Reservation is situated between Billings, Montana, and Sheridan, Wyoming. More so than any other…

Histopathology of humorally mediated anti-glomerular basement membrane (GBM) glomerulonephritis in mice.

PubMed

Le Hir, Michel

2004-07-01

From a diagnostic point of view it would be important to learn more about the relationship between the immune responses underlying glomerulonephritis and the patterns of glomerular lesions. A murine model of anti-GBM glomerulonephritis in which inflammation is driven by delayed-type hypersensitivity (DTH) has been studied extensively. The aim of this study was to uncover histological features that might be specific for anti-GBM glomerulonephritis driven by a humoral immune response. BALB/c mice were immunized with rabbit IgG in incomplete Freund's adjuvant. Six days later, on day 0, they received rabbit anti-GBM serum intravenously. Proteinuria was assessed with dipsticks. Mice were killed on days 4, 8 or 14. Kidneys from days 4 and 8 were processed for immunofluorescence and histology. On day 14 mice were perfusion-fixed for electron microscopy. Proteinuria started on day 3. Autologous IgG and of C3 were found along the GBM. There was only slight infiltration with macrophages and no measurable infiltration by CD4 T cells, indicating the virtual absence of DTH. Besides infiltration with neutrophils there were little histological alterations on day 4. On day 8 many loops were hyalinized. On day 14, cellular crescents were found in 23% of glomeruli. Subendothelial spaces contained hyaline material, cells and fibrin. Podocytes displayed effacement of foot processes and apical microprotrusions. Podocyte bridges were common. These alterations were identical to those reported in the standard model that produces a DTH-like inflammation. The qualitative pattern of histological damage in a murine model of anti-GBM glomerulonephritis does not depend on the underlying immunological process.

Ameliorative effects of arctiin from Arctium lappa on experimental glomerulonephritis in rats.

PubMed

Wu, Jian-Guo; Wu, Jin-Zhong; Sun, Lian-Na; Han, Ting; Du, Jian; Ye, Qi; Zhang, Hong; Zhang, Yu-Guang

2009-11-01

Membranous glomerulonephritis (MGN) remains the most common cause of adult-onset nephrotic syndrome in the world and up to 40% of untreated patients will progress to end-stage renal disease. Although the treatment of MGN with immunosuppressants or steroid hormones can attenuate the deterioration of renal function, numerous treatment-related complications have also been established. In this study, the ameliorative effects of arctiin, a natural compound isolated from the fruits of Arctium lappa, on rat glomerulonephritis induced by cationic bovine serum albumin (cBSA) were determined. After oral administration of arctiin (30, 60, 120 mg/kgd) for three weeks, the levels of serum creatinine (Scr) and blood urea nitrogen (BUN) and 24-h urine protein content markedly decreased, while endogenous creatinine clearance rate (ECcr) significantly increased. The parameters of renal lesion, hypercellularity, infiltration of polymorphonuclear leukocyte (PMN), fibrinoid necrosis, focal and segmental proliferation and interstitial infiltration, were reversed. In addition, we observed that arctiin evidently reduced the levels of malondialdehyde (MDA) and pro-inflammatory cytokines including interleukin-6 (IL-6) and tumor necrosis factor (TNF-alpha), suppressed nuclear factor-kappaB p65 (NF-kappaB) DNA binding activity, and enhanced superoxide dismutase (SOD) activity. These findings suggest that the ameliorative effects of arctiin on glomerulonephritis is carried out mainly by suppression of NF-kappaB activation and nuclear translocation and the decreases in the levels of these pro-inflammatory cytokines, while SOD is involved in the inhibitory pathway of NF-kappaB activation. Arctiin has favorable potency for the development of an inhibitory agent of NF-kappaB and further application to clinical treatment of glomerulonephritis, though clinical studies are required.

Compton Thick AGN in the XMM-COSMOS field

NASA Astrophysics Data System (ADS)

Lanzuisi, G.; Perna, M.; Delvecchio, I.; Berta, S.; Brusa, M.; Gruppioni, C.; Comastri, A.

2016-06-01

I will present results we published in two recent papers (Lanzuisi et al. 2015, A&A 573A 137, Lanzuisi et al. 2015, A≈A 578A 120) on the properties of X-ray selected Compton Thick (CT, NH>10^{24} cm^{-2}) AGN, in the XMM-COSMOS survey. We exploited the rich multi-wavelength dataset available in this field, to show that CT AGN tend to harbor smaller, rapidly growing SMBH with respect to unobscured AGN, and have a higher chance of being hosted by star-forming, merging and post-merger systems. We also demonstrated the detectability of even more heavily obscured AGN (NH>10^{25} cm^{-2}), thanks to a truly multi-wavelength approach in the same field, and to the unrivaled XMM sensitivity. The extreme source detected in this way shows strong evidences of ongoing powerful AGN feedback, detected as blue-shifted wings of high ionization optical emission lines such as [NeV] and [FeVII], as well as of the [OIII] emission line. The results obtained from these works point toward a scenario in which highly obscured AGN occupy a peculiar place in the galaxy-AGN co-evolution process, in which both the host and the SMBH rapidly evolve toward the local relations.

The power of infrared AGN selection in mergers: a theoretical study

NASA Astrophysics Data System (ADS)

Blecha, Laura; Snyder, Gregory F.; Satyapal, Shobita; Ellison, Sara L.

2018-05-01

The role of galaxy mergers in fueling active galactic nuclei (AGN) is still debated, owing partly to selection effects inherent to studies of the merger/AGN connection. In particular, luminous AGN are often obscured in late-stage mergers. Mid-infrared (IR) color selection of dust-enshrouded AGN with, e.g., the Wide-field Infrared Survey Explorer (WISE) has uncovered large new populations of obscured AGN. However, this method is sensitive mainly to AGN that dominate emission from the host. To understand how selection biases affect mid-IR studies of the merger/AGN connection, we simulate the evolution of AGN throughout galaxy mergers. Although mid-IR colors closely trace luminous, obscured AGN, we show that nearly half of merger-triggered AGN are missed with common mid-IR selection criteria, even in late-stage, gas-rich major mergers. At z ⪉ 0.5, where merger signatures and dual nuclei can most easily be detected, we find that a more lenient W1 - W2 >0.5 cut greatly improves completeness without significantly decreasing reliability. Extreme nuclear starbursts are briefly able to mimic this AGN signature, but this is largely irrelevant in mergers, where such starbursts are accompanied by AGN. We propose a two-color cut that yields high completeness and reliability even in starbursting systems. Further, we show that mid-IR color selection very effectively identifies dual AGN hosts, with the highest fraction at the smallest separations (<3 kpc). Thus, many merger hosts of mid-IR AGN should contain unresolved dual AGN; these are ideal targets for high-resolution follow-up, particularly with the James Webb Space Telescope.

Cosmic evolution of stellar quenching by AGN feedback: clues from the Horizon-AGN simulation

NASA Astrophysics Data System (ADS)

Beckmann, R. S.; Devriendt, J.; Slyz, A.; Peirani, S.; Richardson, M. L. A.; Dubois, Y.; Pichon, C.; Chisari, N. E.; Kaviraj, S.; Laigle, C.; Volonteri, M.

2017-11-01

The observed massive end of the galaxy stellar mass function is steeper than its predicted dark matter halo counterpart in the standard Λ cold dark matter paradigm. In this paper, we investigate the impact of active galactic nuclei (AGN) feedback on star formation in massive galaxies. We isolate the impact of AGN by comparing two simulations from the HORIZON suite, which are identical except that one also includes supermassive black holes (SMBHs) and related feedback models. This allows us to cross-identify individual galaxies between simulations and quantify the effect of AGN feedback on their properties, including stellar mass and gas outflows. We find that massive galaxies (M* ≥ 1011 M⊙) are quenched by AGN feedback to the extent that their stellar masses decrease by up to 80 per cent at z = 0. SMBHs affect their host halo through a combination of outflows that reduce their baryonic mass, particularly for galaxies in the mass range 109 M⊙ ≤ M* ≤ 1011 M⊙, and a disruption of central gas inflows, which limits in situ star formation. As a result, net gas inflows on to massive galaxies, M* ≥ 1011 M⊙, drop by up to 70 per cent. We measure a redshift evolution in the stellar mass ratio of twin galaxies with and without AGN feedback, with galaxies of a given stellar mass showing stronger signs of quenching earlier on. This evolution is driven by a progressive flattening of the MSMBH-M* relation with redshift, particularly for galaxies with M* ≤ 1010 M⊙. MSMBH/M* ratios decrease over time, as falling average gas densities in galaxies curb SMBH growth.

Low Mass AGN: Combining IRAC With Near-IR Grism Spectroscopy

NASA Astrophysics Data System (ADS)

Colbert, James; Teplitz, Harry; Malkan, Matt; Scarlata, Claudia; Bagley, Micaela; Baronchelli, Ivano; Hayden-Pawson, Connor; Rafelski, Marc

2017-10-01

Low mass AGN are critical to understanding the evolution of AGNs and stars in galaxies, marking the time periods of highest accretion efficiency and greatest likely deviations from the black hole mass - sigma correlation. Using the WFC3 Infrared Spectroscopic Parallels (WISP), we have just recently identified 68 candidate z > 1 AGN in 27 fields from their near-infrared emission line ratios. The WISP survey selects emission line galaxies without any pre-selection bias and is exquisitely sensitive to low mass (down to 10^7 solar masses), high-equivalent width galaxies that are missed by most other surveys. We propose to take IRAC 4.5 micron imaging of these AGN candidate fields in order to confirm 68 low mass AGN candidates, identify additional low mass IR-AGN missed by emission line selection, and produce the SED fits that can separate hot dust from star light, allowing comparison of stellar mass to AGN bolometric luminosity. The upcoming Euclid and WFIRST missions will generate hundreds of thousands of near-infrared spectra over a similar redshift range to WISP. For most of these objects, near-infrared emission line ratios will be the only viable AGN diagnostic. The Spitzer IRAC color AGN selection is one of the most robust AGN identifiers available. We wish to test these near-infrared emission line selection methods against the IRAC selection in order to evaluate the reliability of the AGN these future missions are likely to produce.

Cyclooxygenase metabolites mediate glomerular monocyte chemoattractant protein-1 formation and monocyte recruitment in experimental glomerulonephritis.

PubMed

Schneider, A; Harendza, S; Zahner, G; Jocks, T; Wenzel, U; Wolf, G; Thaiss, F; Helmchen, U; Stahl, R A

1999-02-01

Monocyte chemoattractant protein-1 (MCP-1) has been shown to play a significant role in the recruitment of monocytes/macrophages in experimental glomerulonephritis. Whereas a number of inflammatory mediators have been characterized that are involved in the expression of MCP-1 in renal disease, little is known about repressors of chemokine formation in vivo. We hypothesized that cyclooxygenase (COX) products influence the formation of MCP-1 and affect inflammatory cell recruitment in glomerulonephritis. The effect of COX inhibitors was evaluated in the antithymocyte antibody model and an anti-glomerular basement membrane model of glomerulonephritis. Rats were treated with the COX-1/COX-2 inhibitor indomethacin and the selective COX-2 inhibitors meloxicam and SC 58125. Animals were studied at 1 hour, 24 hours, and 5 days after induction of the disease. Indomethacin, to a lesser degree the selective COX-2 inhibitors, enhanced glomerular MCP-1 and RANTES mRNA levels. Indomethacin enhanced glomerular monocyte chemoattractant activity an the infiltration of monocytes/macrophages at 24 hours and 5 days. Our studies demonstrate that COX products may serve as endogenous repressors of MCP-1 formation in experimental glomerulonephritis. The data suggest that COX-1 and COX-2 products mediate these effects differently because the selective COX-2 inhibitors had less influence on chemokine expression.

A WISE Selection of MIR AGN in Different Environments

NASA Astrophysics Data System (ADS)

Cheeseboro, Belinda D.; Norman, Dara J.

2015-01-01

This study was undertaken to understand the role of large scale environment in the evolution of MIR-selected AGN. In this study we examine AGN candidates in two types of environments: 7 clusters and 6 blank fields. Two types of clusters were studied in this project: 3 virialized and 4 non-virialized. The redshift of the clusters ranged 0.22≤z≤0.28. We used the mid-infrared WISE All-Sky database to identify AGN, applying various methods to refine our AGN candidate selection. To ascertain if there is an excess or deficit of MIR AGN in galaxy clusters vs. blank fields, we compared the AGN candidate distributions in virialized vs. non-virialized clusters to the blank fields. After close examination and comparison of the results to X-ray selected AGN from the Gilmour et al. (2009) study, we concluded that we do not detect an excess or deficit of MIR AGN in our clusters whether the cluster was virialized or non-virialized. This contrasted the conclusion of the Gilmour et al. (2009) study where there was an excess of X-Ray selected AGN in clusters.We also note an interesting feature in our WISE color-color plots that might be used for further investigation.Cheeseboro was supported by the NOAO/KPNO ResearchExperiences for Undergraduates (REU) Program which is funded by theNational Science Foundation Research Experiences for UndergraduatesProgram (AST-1262829).

Hot Dust Obscured Galaxies with Excess Blue Light: Dual AGN or Single AGN Under Extreme Conditions?

NASA Astrophysics Data System (ADS)

Assef, R. J.; Walton, D. J.; Brightman, M.; Stern, D.; Alexander, D.; Bauer, F.; Blain, A. W.; Diaz-Santos, T.; Eisenhardt, P. R. M.; Finkelstein, S. L.; Hickox, R. C.; Tsai, C.-W.; Wu, J. W.

2016-03-01

Hot dust-obscured galaxies (Hot DOGs) are a population of hyper-luminous infrared galaxies identified by the Wide-field Infrared Survey Explorer (WISE) mission from their very red mid-IR colors, and characterized by hot dust temperatures (T > 60 K). Several studies have shown clear evidence that the IR emission in these objects is powered by a highly dust-obscured active galactic nucleus (AGN) that shows close to Compton-thick absorption at X-ray wavelengths. Thanks to the high AGN obscuration, the host galaxy is easily observable, and has UV/optical colors usually consistent with those of a normal galaxy. Here we discuss a sub-population of eight Hot DOGs that show enhanced rest-frame UV/optical emission. We discuss three scenarios that might explain the excess UV emission: (I) unobscured light leaked from the AGN by reflection over the dust or by partial coverage of the accretion disk; (II) a second unobscured AGN in the system; or (III) a luminous young starburst. X-ray observations can help discriminate between these scenarios. We study in detail the blue excess Hot DOG WISE J020446.13-050640.8, which was serendipitously observed by Chandra/ACIS-I for 174.5 ks. The X-ray spectrum is consistent with a single, hyper-luminous, highly absorbed AGN, and is strongly inconsistent with the presence of a secondary unobscured AGN. Based on this, we argue that the excess blue emission in this object is most likely either due to reflection or a co-eval starburst. We favor the reflection scenario as the unobscured star formation rate needed to power the UV/optical emission would be ≳1000 M⊙ yr-1. Deep polarimetry observations could confirm the reflection hypothesis.

HOT DUST OBSCURED GALAXIES WITH EXCESS BLUE LIGHT: DUAL AGN OR SINGLE AGN UNDER EXTREME CONDITIONS?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Assef, R. J.; Diaz-Santos, T.; Walton, D. J.

Hot dust-obscured galaxies (Hot DOGs) are a population of hyper-luminous infrared galaxies identified by the Wide-field Infrared Survey Explorer (WISE) mission from their very red mid-IR colors, and characterized by hot dust temperatures (T > 60 K). Several studies have shown clear evidence that the IR emission in these objects is powered by a highly dust-obscured active galactic nucleus (AGN) that shows close to Compton-thick absorption at X-ray wavelengths. Thanks to the high AGN obscuration, the host galaxy is easily observable, and has UV/optical colors usually consistent with those of a normal galaxy. Here we discuss a sub-population of eight Hot DOGsmore » that show enhanced rest-frame UV/optical emission. We discuss three scenarios that might explain the excess UV emission: (i) unobscured light leaked from the AGN by reflection over the dust or by partial coverage of the accretion disk; (ii) a second unobscured AGN in the system; or (iii) a luminous young starburst. X-ray observations can help discriminate between these scenarios. We study in detail the blue excess Hot DOG WISE J020446.13–050640.8, which was serendipitously observed by Chandra/ACIS-I for 174.5 ks. The X-ray spectrum is consistent with a single, hyper-luminous, highly absorbed AGN, and is strongly inconsistent with the presence of a secondary unobscured AGN. Based on this, we argue that the excess blue emission in this object is most likely either due to reflection or a co-eval starburst. We favor the reflection scenario as the unobscured star formation rate needed to power the UV/optical emission would be ≳1000 M{sub ⊙} yr{sup −1}. Deep polarimetry observations could confirm the reflection hypothesis.« less

Star Formation of Merging Disk Galaxies with AGN Feedback Effects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, Jongwon; Smith, Rory; Yi, Sukyoung K., E-mail: jw.park@yonsei.ac.kr

2017-08-20

Using a numerical hydrodynamics code, we perform various idealized galaxy merger simulations to study the star formation (SF) of two merging disk galaxies. Our simulations include gas accretion onto supermassive black holes and active galactic nucleus (AGN) feedback. By comparing AGN simulations with those without AGNs, we attempt to understand when the AGN feedback effect is significant. Using ∼70 simulations, we investigate SF with the AGN effect in mergers with a variety of mass ratios, inclinations, orbits, galaxy structures, and morphologies. Using these merger simulations with AGN feedback, we measure merger-driven SF using the burst efficiency parameter introduced by Coxmore » et al. We confirm previous studies which demonstrated that, in galaxy mergers, AGN suppresses SF more efficiently than in isolated galaxies. However, we also find that the effect of AGNs on SF is larger in major than in minor mergers. In minor merger simulations with different primary bulge-to-total ratios, the effect of bulge fraction on the merger-driven SF decreases due to AGN feedback. We create models of Sa-, Sb-, and Sc-type galaxies and compare their SF properties while undergoing mergers. With the current AGN prescriptions, the difference in merger-driven SF is not as pronounced as in the recent observational study of Kaviraj. We discuss the implications of this discrepancy.« less

[A case of Grave's disease with MPO-ANCA-associated glomerulonephritis during propylthiouracil (PTU) therapy following interstitial pneumonitis].

PubMed

Saeki, T; Miyamura, S; Nakano, M; Arakawa, M

1997-03-01

A 68-year-old man who developed MPO-ANCA-associated glomerulonephritis during propylthiouracil (PTU) treatment is reported. In 1986, he was diagnosed as having interstitial pneumonitis. Although he tested positive for antinuclear antibody and rheumatoid factor, he had no symptoms and was followed up without therapy. Five years later, the diagnosis of Graves's disease was made after complaints of body weight loss, diplopia and exophthalmos. Tests showed positivity for anti-thyroid stimulating hormone (TSH) receptor antibody, antithyroidperoxidase antibody and antithyroglobulin antibody. He was treated with PTU and prednisolone for four years. In November 1995, hematuria and proteinuria developed, and renal function deteriorated rapidly. A renal biopsy revealed crescentic glomerulonephritis and the serum titer of MPO-ANCA was markedly elevated. He was treated with a high dose of prednisolone and cyclophosphamide. Although the serum creatinine level gradually decreased, irreversible renal dysfunction persisted. In this patient, the presence of various autoantibodies had been recognized for several years before MPO-ANCA-associated glomerulonephritis developed. Polyclonal B-cell activation and PTU treatment may have played a role in the pathogenesis of MPO-ANCA-associated glomerulonephritis.

Mini-Survey on SDSS OIII AGN with Swift

NASA Technical Reports Server (NTRS)

Angelini, Lorella

2008-01-01

The number of AGN and their luminosity distribution are crucial parameters for our understanding of the AGN phenomenon. There is a common wisdom that every massive galaxy has a massive black hole. However, most of these objects either are not radiating or until recently have been very difficult to detect. The Sloan Digital Sky Survey (SDSS) data, based on the [OIII] line indicate that perhaps up to 20% of all galaxies may be classified as AGN a surprising result that must be checked with independent data. X-ray surveys have revealed that hard X-ray selected AGN show a strong luminosity dependent evolution and their luminosity function (LF) shows a dramatic break towards low $L_X$ (at all $z$). This is seen for all types of AGN, but is stronger for the broad-line objects. In sharp contrast, the local LF of {it optically-selected samples} shows no such break and no differences between narrow and broad-line objects. Assuming both hard X-ray and [O{\\sc iii}] emission are fair indicators of AGN activity, it is important to understand this discrepancy. We present here the results of a min-survey done with Swift on a selected sample of SDSS selected AGN. The objects have been sampled at different L([O{\\sc iii}]) to check the relation with the $L_X$ observed with Swift.

Challenges in Finding AGNs in the Low Luminosity Regime

NASA Astrophysics Data System (ADS)

Satyapal, Shobita; Abel, Nick; Secrest, Nathan; Singh, Amrit; Ellison, Sara

2016-08-01

Low luminosity AGNs are an important component of the AGN population. They are often found in the lowest mass galaxies or galaxies that lack classical bulges, a demographic that places important constraints to models of supermassive black hole seed formation and merger-free models of AGN fueling. The detection of AGNs in this low luminosity regime is challenging both because star formation in the host galaxy can dominate the optical spectrum and gas and dust can obscure the central engine at both optical and X-ray wavelengths. Thus while mid-infrared color selection and X-ray observations at energies <10 keV are often powerful tools in uncovering optically unidentified AGNs at higher luminosities, this is not the case in the low luminosity regime. In this talk, I will review the effectiveness of uncovering AGNs in the low luminosity regime using multiwavength investigations, with a focus on infrared spectroscopic signatures.

Does the obscured AGN fraction really depend on luminosity?

NASA Astrophysics Data System (ADS)

Sazonov, S.; Churazov, E.; Krivonos, R.

2015-12-01

We use a sample of 151 local non-blazar active galactic nuclei (AGN) selected from the INTEGRAL all-sky hard X-ray survey to investigate if the observed declining trend of the fraction of obscured (i.e. showing X-ray absorption) AGN with increasing luminosity is mostly an intrinsic or selection effect. Using a torus-obscuration model, we demonstrate that in addition to negative bias, due to absorption in the torus, in finding obscured AGN in hard X-ray flux-limited surveys, there is also positive bias in finding unobscured AGN, due to Compton reflection in the torus. These biases can be even stronger taking into account plausible intrinsic collimation of hard X-ray emission along the axis of the obscuring torus. Given the AGN luminosity function, which steepens at high luminosities, these observational biases lead to a decreasing observed fraction of obscured AGN with increasing luminosity even if this fraction has no intrinsic luminosity dependence. We find that if the central hard X-ray source in AGN is isotropic, the intrinsic (i.e. corrected for biases) obscured AGN fraction still shows a declining trend with luminosity, although the intrinsic obscured fraction is significantly larger than the observed one: the actual fraction is larger than ˜85 per cent at L ≲ 1042.5 erg s-1 (17-60 keV), and decreases to ≲60 per cent at L ≳ 1044 erg s-1. In terms of the half-opening angle θ of an obscuring torus, this implies that θ ≲ 30° in lower luminosity AGN, and θ ≳ 45° in higher luminosity ones. If, however, the emission from the central supermassive black hole is collimated as dL/dΩ ∝ cos α, the intrinsic dependence of the obscured AGN fraction is consistent with a luminosity-independent torus half-opening angle θ ˜ 30°.

AGN feedback compared: jets versus radiation

NASA Astrophysics Data System (ADS)

Cielo, Salvatore; Bieri, Rebekka; Volonteri, Marta; Wagner, Alexander Y.; Dubois, Yohan

2018-06-01

Feedback by active galactic nuclei (AGNs) is often divided into quasar and radio mode, powered by radiation or radio jets, respectively. Both are fundamental in galaxy evolution, especially in late-type galaxies, as shown by cosmological simulations and observations of jet-ISM (interstellar medium) interactions in these systems. We compare AGN feedback by radiation and by collimated jets through a suite of simulations, in which a central AGN interacts with a clumpy, fractal galactic disc. We test AGNs of 1043 and 1046 erg s-1, considering jets perpendicular or parallel to the disc. Mechanical jets drive the more powerful outflows, exhibiting stronger mass and momentum coupling with the dense gas, while radiation heats and rarefies the gas more. Radiation and perpendicular jets evolve to be quite similar in outflow properties and effect on the cold ISM, while inclined jets interact more efficiently with all the disc gas, removing the densest 20 {per cent} in 20 Myr, and thereby reducing the amount of cold gas available for star formation. All simulations show small-scale inflows of 0.01-0.1 M⊙ yr-1, which can easily reach down to the Bondi radius of the central supermassive black hole (especially for radiation and perpendicular jets), implying that AGNs modulate their own duty cycle in a feedback/feeding cycle.

Identifying Luminous AGN in Deep Surveys: Revised IRAC Selection Criteria

NASA Astrophysics Data System (ADS)

Donley, Jennifer; Koekemoer, A. M.; Brusa, M.; Capak, P.; Cardamone, C. N.; Civano, F.; Ilbert, O.; Impey, C. D.; Kartaltepe, J.; Miyaji, T.; Salvato, M.; Sanders, D. B.; Trump, J. R.; Zamorani, G.

2012-01-01

Spitzer IRAC selection is a powerful tool for identifying luminous AGN. The AGN selection wedges currently in use, however, are heavily contaminated by star-forming galaxies, especially at high redshift. Using the large samples of luminous AGN and high-redshift star-forming galaxies in COSMOS, we redefine the AGN selection criteria for use in deep IRAC surveys. The new IRAC criteria are designed to be both highly complete and reliable, and incorporate the best aspects of the current AGN selection wedges and of infrared power-law selection while excluding high redshift star-forming galaxies selected via the BzK, DRG, LBG, and SMG criteria. At QSO-luminosities of log L(2-10 keV)>44, the new IRAC criteria recover 75% of the hard X-ray and IRAC-detected XMM-COSMOS sample, yet only 37% of the IRAC AGN candidates have X-ray counterparts, a fraction that rises to 51% in regions with Chandra exposures of 50-160 ks. X-ray stacking of the individually X-ray non-detected AGN candidates leads to a hard X-ray signal indicative of heavily obscured to mildly Compton-thick obscuration (log NH >= 23.7). While IRAC selection recovers a substantial fraction of luminous unobscured and obscured AGN, it is incomplete to low-luminosity and host-dominated AGN.

Delayed or No Feedback? Gas Outflows in Type 2 AGNs. III

DOE Office of Scientific and Technical Information (OSTI.GOV)

Woo, Jong-Hak; Son, Donghoon; Bae, Hyun-Jin, E-mail: woo@astro.snu.ac.kr, E-mail: hjbae@galaxy.yonsei.ac.kr

2017-04-20

We present gas kinematics based on the [O iii] λ 5007 line and their connection to galaxy gravitational potential, active galactic nucleus (AGN) energetics, and star formation, using a large sample of ∼110,000 AGNs and star-forming (SF) galaxies at z < 0.3. Gas and stellar velocity dispersions are comparable to each other in SF galaxies, indicating that the ionized gas kinematics can be accounted by the gravitational potential of host galaxies. In contrast, AGNs clearly show non-gravitational kinematics, which is comparable to or stronger than the virial motion caused by the gravitational potential. The [O iii] velocity–velocity dispersion (VVD) diagrammore » dramatically expands toward high values as a function of AGN luminosity, implying that the outflows are AGN-driven, while SF galaxies do not show such a trend. We find that the fraction of AGNs with a signature of outflow kinematics, steeply increases with AGN luminosity and Eddington ratio. In particular, the majority of luminous AGNs presents strong non-gravitational kinematics in the [O iii] profile. AGNs with strong outflow signatures show on average similar specific star formation rates (sSFRs) to those of star-forming galaxies. In contrast, AGNs with weak or no outflows have an order of magnitude lower sSFRs, suggesting that AGNs with current strong outflows do now show any negative AGN feedback and that it may take dynamical time to impact on star formation over galactic scales.« less

Internal Kinematics of AGN Hosts

NASA Astrophysics Data System (ADS)

Masegosa, Josefa; Márquez, Isabel; Durret, Florence; DEGAS Consortium

In order to understand the fueling mechanism to power AGNs, a large effort has been done by the DEGAS (Dynamics and nuclear Engine of GAlaxies of Spiral type) consortium to collect the necessary observational material. We defined an AGN sample which is not contaminated by interacting galaxies and a control sample made of normal spirals with the same properties than the AGN sample, i.e. luminosity and redshift distribution, morphology and percentage of bars. In total we have analyzed a sample of 17 active galaxies and 16 normal spirals. All the galaxies are isolated with the following criteria: not having a companion within 0.4 Mpc and cz < 500 km/s. We want to stress this aspect of our sample, since claimed differences between active and normal galaxies (Knapen et al. 2000) disappear when the samples are decontaminated of interacting systems.

AGN outflows and feedback twenty years on

NASA Astrophysics Data System (ADS)

Harrison, C. M.; Costa, T.; Tadhunter, C. N.; Flütsch, A.; Kakkad, D.; Perna, M.; Vietri, G.

2018-03-01

It is twenty years since the seminal works by Magorrian and co-authors and by Silk and Rees, which, along with other related work, ignited an explosion of publications connecting active galactic nucleus (AGN)-driven outflows to galaxy evolution. With a surge in observations of AGN outflows, studies are attempting to test AGN feedback models directly using the outflow properties. With a focus on outflows traced by optical and CO emission lines, we discuss significant challenges that greatly complicate this task, from both an observational and theoretical perspective. We highlight the observational uncertainties involved and the assumptions required when deriving kinetic coupling efficiencies (that is, outflow kinetic power as a fraction of AGN luminosity) from typical observations. Based on recent models we demonstrate that extreme caution should be taken when comparing observationally derived kinetic coupling efficiencies to coupling efficiencies from fiducial feedback models.

Studying AGN Jets At Extreme Angular Resolution

NASA Astrophysics Data System (ADS)

Bruni, Gabriele

2016-10-01

RadioAstron is a 10m antenna orbiting on the Russian Speckt-R spacecraft, launched in 2011. Performing radio interferometry with a global array of ground telescopes, it is providing record angular resolution. The Key Science Project on AGN polarization is exploiting it to study in great detail the configuration of magnetic fields in AGN jets, and understand their formation and collimation. To date, the project has already achieved the highest angular resolution image ever obtained in Astronomy, and detected brightness temperatures exceeding the ones predicted by theory of AGN.

Evaluation of clinical and laboratory findings in pediatric post-streptococcal glomerulonephritis.

PubMed

Kılıc, Beltinge Demircioglu; Kara, Mehtap Akbalık; Buyukcelik, Mithat; Balat, Ayse

2018-05-05

Acute post-streptococcal glomerulonephritis (APSGN) is the most common postinfectious glomerulonephritis in childhood. In this study, we aimed to determine the possible risk factor(s), responsible for decreased glomerular filtration rate (GFR) in APSGN. The data of patients followed up with the diagnosis of APSGN in the Pediatric Nephrology Clinic of Gaziantep University Hospital between October 2014 and October 2016 were retrospectively evaluated. Total number of subjects was 75 (Male/Female:42/33) with the mean age of 8.20±3.25 years. Most common presentations were edema (86.7%), macroscopic hematuria (82.7%) and hypertension (73.3%, n=55). In laboratory examination, 28 children (37.3%) had hypoalbuminemia, 58 (77.3%) had proteinuria, 20 (26.7%) had increased C reactive protein (CRP), while 74 (98.7%) and 12 (16%) of them had decreased C3 and C4 levels, respectively. The number of children with GFR value <90 ml/min/1.73/m2 was 22 (29.3%). The risk of decreased GFR was significantly higher in patients with increased CRP (p:0.001,OR:3.58), hypoalbuminemia (p:0.006,OR:4.83), and decreased C4 level (p:0.010,OR:11.53). Additionally, white blood cell (WBC), neutrophil count, and neutrophil-lymphocyte ratio (NLR) were significantly higher (p:0.02, p:0.006, p:0.004, respectively) in patients with low GFR. Although the prognosis of APSGN in children is good, severe systemic complications and renal failure may develop during the follow-up period. We suggest that decreased C4 level, presence of hypoalbuminemia, increased inflammatory markers (WBC, CRP, neutrophil count and NLR) might be possible risk factors for severity of renal involvement. Especially decreased C4 level may be a risk factor for decreased GFR in those children. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

The host galaxies of ultra hard X-ray selected AGN

NASA Astrophysics Data System (ADS)

Koss, Michael J.

One of the great mysteries surrounding active galactic nuclei (AGN) is their triggering mechanism. Since the discovery that almost all massive galaxies host nuclear supermassive black holes, it has become clear that a trigger mechanism is required to 'turn on' and continue to fuel the central black hole. While it is established that accretion processes are responsible for the energy emitted, the source of the accreting material is still controversial. Furthermore, the energy input from phases of black hole growth is thought to be a key regulator in the formation of galaxies and the establishment of various scaling relations. Theorists often invoke galaxy mergers as the violent mechanism to drive gas into the central regions and ignite luminous quasars, but among more common moderate luminosity AGN, there has been great controversy whether secular processes or mergers dominate AGN fueling. A survey in the ultra hard X-ray band (14--195 keV) is an important new way to answer the fundamental question of AGN fueling. This method is independent of selection effects such as dust extinction and obscuration that plague surveys at other wavelengths because of the ability of the primary continuum to easily pass through large columns of obscuring gas and dust (<10 24 cm-2). In this PhD, we have assembled the largest sample of ultra hard X-ray selected AGN with host galaxy optical data to date, with 185 nearby (z<0.05), moderate luminosity AGN from the Swift BAT sample. We find that these AGN show much higher rates of both mergers and massive spirals suggesting both mergers and accretion of cold gas in late type systems are important in AGN fueling. We also find that the most common AGN survey technique, optical line diagnostics, is heavily biased against finding AGN in mergers or spirals. Finally, in agreement with the merger driven AGN link, we find that dual AGN systems may be more common than current observation suggest since some of them are only detected using high

Average Heating Rate of Hot Atmospheres in Distant Galaxy Clusters by Radio AGN: Evidence for Continuous AGN Heating

NASA Astrophysics Data System (ADS)

Ma, Cheng-Jiun; McNamara, B.; Nulsen, P.; Schaffer, R.

2011-09-01

X-ray observations of nearby clusters and galaxies have shown that energetic feedback from AGN is heating hot atmospheres and is probably the principal agent that is offsetting cooling flows. Here we examine AGN heating in distant X-ray clusters by cross correlating clusters selected from the 400 Square Degree X-ray Cluster survey with radio sources in the NRAO VLA Sky Survey. The jet power for each radio source was determined using scaling relations between radio power and cavity power determined for nearby clusters, groups, and galaxies with atmospheres containing X-ray cavities. Roughly 30% of the clusters show radio emission above a flux threshold of 3 mJy within the central 250 kpc that is presumably associated with the brightest cluster galaxy. We find no significant correlation between radio power, hence jet power, and the X-ray luminosities of clusters in redshift range 0.1 -- 0.6. The detection frequency of radio AGN is inconsistent with the presence of strong cooling flows in 400SD, but cannot rule out the presence of weak cooling flows. The average jet power of central radio AGN is approximately 2 10^{44} erg/s. The jet power corresponds to an average heating of approximately 0.2 keV/particle for gas within R_500. Assuming the current AGN heating rate remained constant out to redshifts of about 2, these figures would rise by a factor of two. Our results show that the integrated energy injected from radio AGN outbursts in clusters is statistically significant compared to the excess entropy in hot atmospheres that is required for the breaking of self-similarity in cluster scaling relations. It is not clear that central AGN in 400SD clusters are maintained by a self-regulated feedback loop at the base of a cooling flow. However, they may play a significant role in preventing the development of strong cooling flows at early epochs.

Characterisation of a candidate dual AGN

NASA Astrophysics Data System (ADS)

Lena, D.; Panizo-Espinar, G.; Jonker, P. G.; Torres, M.; Heida, M.

2018-05-01

We present Chandra and optical observations of a candidate dual AGN discovered serendipitously while searching for recoiling black holes via a cross-correlation between the serendipitous XMM source catalog (2XMMi) and SDSS-DR7 galaxies with a separation no larger than ten times the sum of their Petrosian radii. The system has a stellar mass ratio M1/M2 ≈ 0.7. One of the galaxies (Source 1) shows clear evidence for AGN activity in the form of hard X-ray emission and optical emission-line diagnostics typical of AGN ionisation. The nucleus of the other galaxy (Source 2) has a soft X-ray spectrum, bluer colours, and optical emission line ratios dominated by stellar photoionisation with a "composite" signature, which might indicate the presence of a weak AGN. When plotted on a diagram with X-ray luminosity vs [OIII] luminosity both nuclei fall within the locus defined by local Seyfert galaxies. From the optical spectrum we estimate the electron densities finding n1 < 27 e- cm-3 and n2 ≈ 200 e- cm-3. From a 2D decomposition of the surface brightness distribution we infer that both galaxies host rotationally supported bulges (Sersic index <1). While the active nature of Source 1 can be established with confidence, whether the nucleus of Source 2 is active remains a matter of debate. Evidence that a faint AGN might reside in its nucleus is, however, tantalising.

Characterization of a candidate dual AGN

NASA Astrophysics Data System (ADS)

Lena, D.; Panizo-Espinar, G.; Jonker, P. G.; Torres, M. A. P.; Heida, M.

2018-07-01

We present Chandra and optical observations of a candidate dual active galactic nucleus (AGN) discovered serendipitously while searching for recoiling black holes via a cross-correlation between the serendipitous XMM source catalogue (2XMMi) and SDSS-DR7 galaxies with a separation no larger than 10 times the sum of their Petrosian radii. The system has a stellar mass ratio M1/M2 ≈ 0.7. One of the galaxies (Source 1) shows clear evidence for AGN activity in the form of hard X-ray emission and optical emission-line diagnostics typical of AGN ionization. The nucleus of the other galaxy (Source 2) has a soft X-ray spectrum, bluer colours, and optical emission-line ratios dominated by stellar photoionization with a `composite' signature, which might indicate the presence of a weak AGN. When plotted on a diagram with X-ray luminosity versus [OIII] luminosity, both nuclei fall within the locus defined by local Seyfert galaxies. From the optical spectrum, we estimate the electron densities finding n1 < 27 e- cm-3 and n2 ≈ 200 e- cm-3. From a 2D decomposition of the surface brightness distribution, we infer that both galaxies host rotationally supported bulges (Sérsic index <1). While the active nature of Source 1 can be established with confidence, whether the nucleus of Source 2 is active remains a matter of debate. Evidence that a faint AGN might reside in its nucleus is, however, tantalizing.

X-ray Absorbers as Probes of AGN Unification

NASA Astrophysics Data System (ADS)

Kazannas, Demosthenes

We have developed, over the past few years, models of photoionized MHD winds off black hole accretion disks and showed that their properties are consistent with those of the AGN warm absorbers and those of the tori invoked in AGN unification schemes. Furthermore, we have shown that these models are sufficiently robust to reproduce the absorber properties (UV and X-ray) in AGN classes as diverse as Seyferts and BAL QSOs.With this proposal we request funding to model archival spectroscopic data of eighteen AGN with photoionized MHD winds. Successful implementation of this program will provide for the first time an association of the properties of warm absorbers with the parameters of a well-defined physical model, namely their density profiles, mass fluxes and inclination angles. Furthermore, determination of these parameters for our AGN sample will allow a statistical analysis of their properties and, as such, a better understanding of the properties of AGN structure. The value of our models lies in their simplicity: the winds are essentially analytic with only a small number of parameters. This simplicity makes possible the generation of a large grid of models which will be made available to the community through XSPEC/mtable for analysis of similar data by the observers.

Evaluation of the ameliorative effects of immunosuppressants on crescentic glomerulonephritis in SCG/Kj mice.

PubMed

Saiga, Kan; Yoshida, Minako; Nakamura, Iwao; Toyoda, Eriko; Tokunaka, Kazuhiro; Morohashi, Hirohisa; Abe, Fuminori; Nemoto, Kyuichi; Nose, Masato

2008-09-01

The therapeutic efficacy of immunosuppressants for treating rapidly progressive glomerulonephritis (RPGN) with crescent formation remains controversial. SCG/Kj mice spontaneously develop RPGN-like symptoms, characteristic of crescentic glomerulonephritis and systemic small vessel vasculitis, associated with the presence of anti-neutrophil cytoplasmic antibodies (ANCA). We evaluated the "ameliorative", not prophylactic, effects of immunosuppressive agents, deoxyspergualin (DSG), cyclophosphamide (CYC) and prednisolone (PDN), on RPGN in these mice. DSG at intraperitoneal doses of 3 and 6 mg/kg, CYC at an oral dose of 12 mg/kg, or PDN at an intraperitoneal dose of 120 mg/kg was administered once a day for 21 days to female mice "at the onset of hematuria". A set of control SCG/Kj mice received only saline injections. DSG and CYC significantly prolonged survival, improved the proteinuria, hematuria and hyperuremia, and decreased the serum level of myeloperoxidase-ANCA. Moreover, DSG significantly suppressed the formation of crescents in glomeruli. PDN failed to affect any of the parameters. DSG might be useful for inducing remission in crescentic glomerulonephritis involved in RPGN.

Disentangling AGN and Star Formation in Soft X-Rays

NASA Technical Reports Server (NTRS)

LaMassa, Stephanie M.; Heckman, T. M.; Ptak, A.

2012-01-01

We have explored the interplay of star formation and active galactic nucleus (AGN) activity in soft X-rays (0.5-2 keV) in two samples of Seyfert 2 galaxies (Sy2s). Using a combination of low-resolution CCD spectra from Chandra and XMM-Newton, we modeled the soft emission of 34 Sy2s using power-law and thermal models. For the 11 sources with high signal-to-noise Chandra imaging of the diffuse host galaxy emission, we estimate the luminosity due to star formation by removing the AGN, fitting the residual emission. The AGN and star formation contributions to the soft X-ray luminosity (i.e., L(sub x,AGN) and L(sub x,SF)) for the remaining 24 Sy2s were estimated from the power-law and thermal luminosities derived from spectral fitting. These luminosities were scaled based on a template derived from XSINGS analysis of normal star-forming galaxies. To account for errors in the luminosities derived from spectral fitting and the spread in the scaling factor, we estimated L(sub x,AGN) and L(sub x,SF))from Monte Carlo simulations. These simulated luminosities agree with L(sub x,AGN) and L(sub x,SF) derived from Chandra imaging analysis within a 3sigma confidence level. Using the infrared [Ne ii]12.8 micron and [O iv]26 micron lines as a proxy of star formation and AGN activity, respectively, we independently disentangle the contributions of these two processes to the total soft X-ray emission. This decomposition generally agrees with L(sub x,SF) and L(sub x,AGN) at the 3 sigma level. In the absence of resolvable nuclear emission, our decomposition method provides a reasonable estimate of emission due to star formation in galaxies hosting type 2 AGNs.

Lyman continuum leaking AGN in the SSA22 field

NASA Astrophysics Data System (ADS)

Micheva, Genoveva; Iwata, Ikuru; Inoue, Akio K.

2017-02-01

Subaru/SuprimeCam narrow-band photometry of the SSA22 field reveals the presence of four Lyman continuum (LyC) candidates among a sample of 14 active galactic nuclei (AGNs). Two show offsets and likely have stellar LyCin nature or are foreground contaminants. The remaining two LyC candidates are type I AGN. We argue that the average LyC escape fraction of high-redshift, low-luminosity AGN is not likely to be unity, as often assumed in the literature. From direct measurement we obtain the average LyC-to-UV flux density ratio and ionizing emissivity for a number of AGN classes and find it at least a factor of 2 lower than values obtained assuming fesc = 1. Comparing to recent Ly α forest measurements, AGNs at redshift z ˜ 3 make up at most ˜12 per cent and as little as ˜5 per cent of the total ionizing budget. Our results suggest that AGNs are unlikely to dominate the ionization budget of the Universe at high redshifts.

Reverberation Mapping of AGN Accretion Disks

NASA Astrophysics Data System (ADS)

Fausnaugh, Michael; AGN STORM Collaboration

2017-01-01

I will discuss new reverberation mapping results that allow us to investigate the temperature structure of AGN accretion disks. By measuring time-delays between broad-band continuum light curves, we can determine the size of the disk as a function of wavelength. I will discuss the detection of continuum lags in NGC 5548 reported by the AGN STORM project and implications for the accretion disk. I will also present evidence for continuum lags in two other AGN for which we recently measured black hole masses from continuum-Hbeta reverberations. The mass measurements allow us to compare the continuum lags to predictions from standard thin disk theory, and our results indicate that the accretion disks are larger than the simplest expectations.

The Search for AGN in Dusty Star Forming Hosts with JWST

NASA Astrophysics Data System (ADS)

Kirkpatrick, Allison; Alberts, Stacey; Pope, Alexandra; Rieke, George; Sajina, Anna

2018-01-01

The bulk of the stellar growth over cosmic time is dominated by IR luminous galaxies at cosmic noon (z=1-2), many of which harbor a hidden active galactic nucleus (AGN). I use state of the art infrared color diagnostics, combining Spitzer and Herschel observations, to separate dust-obscured AGN from dusty star forming galaxies (SFGs) in the CANDELS and COSMOS surveys. I calculate 24 micron counts of SFGs, AGN/star forming "Composites", and AGN. AGN and Composites dominate the counts above 0.8 mJy at 24 micron, and Composites form at least 25% of an IR sample even to faint detection limits. I develop methods to use the Mid-Infrared Instrument (MIRI) on JWST to identify dust-obscured AGN and Composite galaxies from z~1-2. I demonstrate that MIRI color techniques can select AGN with lower Eddington ratios and higher specific SFRs than X-ray techniques alone. JWST/MIRI will enable critical steps forward in identifying and understanding dust-obscured AGN and the link to their host galaxies.

Selecting AGN through Variability in SN Datasets

NASA Astrophysics Data System (ADS)

Boutsia, K.; Leibundgut, B.; Trevese, D.; Vagnetti, F.

2010-07-01

Variability is a main property of Active Galactic Nuclei (AGN) and it was adopted as a selection criterion using multi epoch surveys conducted for the detection of supernovae (SNe). We have used two SN datasets. First we selected the AXAF field of the STRESS project, centered in the Chandra Deep Field South where, besides the deep X-ray surveys also various optical catalogs exist. Our method yielded 132 variable AGN candidates. We then extended our method including the dataset of the ESSENCE project that has been active for 6 years, producing high quality light curves in the R and I bands. We obtained a sample of ˜4800 variable sources, down to R=22, in the whole 12 deg2 ESSENCE field. Among them, a subsample of ˜500 high priority AGN candidates was created using as secondary criterion the shape of the structure function. In a pilot spectroscopic run we have confirmed the AGN nature for nearly all of our candidates.

A Chandra-Swift View of Point Sources in Hickson Compact Groups: High AGN Fraction but a Dearth of Strong AGNs

NASA Astrophysics Data System (ADS)

Tzanavaris, P.; Gallagher, S. C.; Hornschemeier, A. E.; Fedotov, K.; Eracleous, M.; Brandt, W. N.; Desjardins, T. D.; Charlton, J. C.; Gronwall, C.

2014-05-01

We present Chandra X-ray point source catalogs for 9 Hickson Compact Groups (HCGs, 37 galaxies) at distances of 34-89 Mpc. We perform detailed X-ray point source detection and photometry and interpret the point source population by means of simulated hardness ratios. We thus estimate X-ray luminosities (LX ) for all sources, most of which are too weak for reliable spectral fitting. For all sources, we provide catalogs with counts, count rates, power-law indices (Γ), hardness ratios, and LX , in the full (0.5-8.0 keV), soft (0.5-2.0 keV), and hard (2.0-8.0 keV) bands. We use optical emission-line ratios from the literature to re-classify 24 galaxies as star-forming, accreting onto a supermassive black hole (AGNs), transition objects, or low-ionization nuclear emission regions. Two-thirds of our galaxies have nuclear X-ray sources with Swift/UVOT counterparts. Two nuclei have L X, 0.5-8.0 keV >1042 erg s-1, are strong multi-wavelength active galactic nuclei (AGNs), and follow the known αOX-νL ν (nearUV) correlation for strong AGNs. Otherwise, most nuclei are X-ray faint, consistent with either a low-luminosity AGN or a nuclear X-ray binary population, and fall in the "non-AGN locus" in αOX-νL ν (nearUV) space, which also hosts other normal galaxies. Our results suggest that HCG X-ray nuclei in high specific star formation rate spiral galaxies are likely dominated by star formation, while those with low specific star formation rates in earlier types likely harbor a weak AGN. The AGN fraction in HCG galaxies with MR <= -20 and L X, 0.5-8.0 keV >=1041 erg s-1 is 0.08^{+0.35}_{-0.01}, somewhat higher than the ~5% fraction in galaxy clusters.

Towards A Complete Census of the Compton-thick AGN population and the NH Distribution of AGN in the Local Universe.

NASA Astrophysics Data System (ADS)

Annuar, A.

2015-09-01

We present updated results from an ongoing project to establish the most unbiased census of the Compton- thick active galactic nucleus (CTAGN) population and the intrinsic column density (NH) distribution of the overall AGN population in the local universe, using a sample of mid-infrared (mid-IR) selected AGN within 15 Mpc. We find that 20% of the AGN in the sample are bona-fide CTAGN based upon hard X-ray studies (E > 10 keV). More candidates are then selected using multiwavelength techniques, i.e. mid-IR:X-ray and optical [OIII]5007:X-ray flux ratios. Based on these analyses along with evidence from previous literature, we initially find a further 25% of potential candidates. We then observed two of these candidates, NGC 5643 and NGC 3486, using NuSTAR and is able to confirm the former as a CTAGN and rule out the latter as an obscured AGN. This constrains the total CTAGN population in the sample to 25-40%, though it could potentially be as high as 65% accounting for those that still lack data. Finally, we use these results to estimate the intrinsic NH distribution of the local AGN population. Two more of our CTAGN candidates are scheduled to be observed by NuSTAR, bringing the completeness of hard X-ray energy data of the sample to 65%. This work provides a well-defined local benchmark for AGN unification studies.

Luminous Obscured AGN Unveiled in the Stripe 82 X-ray Survey

NASA Astrophysics Data System (ADS)

LaMassa, Stephanie; Glikman, Eilat; Brusa, Marcella; Rigby, Jane; Tasnim Ananna, Tonima; Stern, Daniel; Lira, Paulina; Urry, Meg; Salvato, Mara; Alexandroff, Rachael; Allevato, Viola; Cardamone, Carolin; Civano, Francesca Maria; Coppi, Paolo; Farrah, Duncan; Komossa, S.; Lanzuisi, Giorgio; Marchesi, Stefano; Richards, Gordon; Trakhtenbrot, Benny; Treister, Ezequiel

2018-01-01

Stripe 82X is a wide-area (30 deg2) X-ray survey overlapping the legacy Sloan Digital Sky Survey (SDSS) Stripe 82 field, designed to uncover rare, high luminosity active galactic nuclei (AGN). We report on the results of an on-going near-infrared (NIR) spectroscopic campaign to follow-up reddened AGN candidates with Palomar TripleSpec, Keck NIRSPEC, and Gemini GNIRS. We identified 8 AGN in our bright NIR sample (K < 16, Vega), selected to have red R-K colors (> 4, Vega); four of these sources had existing optical spectra in SDSS. We targeted four out of 34 obscured AGN candidates in our faint NIR sample (K > 17, Vega), all of which are undetected in the single-epoch SDSS imaging, making them the best candidates for the most obscured and/or the most distant reddend AGN in Stripe 82X. All twelve sources are Type 1 AGN, with the FWHM of at least one permitted emission line exceeding 1300 km/s. We find that our nearly complete bright NIR sample (12/13 obscured AGN candidates have spectroscopic redshifts) is more distant (z > 0.5) than a matched sample of blue Type 1 AGN from Stripe 82X; these AGN tend to be more luminous than their blue, unobscured counterparts. Results from our pilot program of faint NIR-selected obscured AGN candidates demonstrate that our selection recovers reddened quasars missed by SDSS.

Treatment of a case of mesangioproliferative glomerulonephritis secondary to Echinococcus alveolaris with albendazole.

PubMed

Ulusoy, Sükrü; Ozkan, Gülsüm; Mungan, Sevdegül; Arslan, Mehmet; Cansu, Ayşegül; Cansiz, Muammer; Köseoğlu, Rahman; Kaynar, Kübra

2011-01-01

Parasitic infections lead to significant morbidity and mortality, especially in tropical regions. The renal damage caused by these infections occurs via various mechanisms. Two forms of parasitic echinococcus infection widely responsible for infection in humans are Echinococcus granulosus and Echinococcus multilocularis. E. multilocularis causes Alveolar echinococcus infection in humans. Alveolar echinococcus has high mortality, and the possible limits of surgery are generally exceeded by the time of diagnosis. The literature contains no case reports of comorbidity of alveolar echinococcus and glomerulonephritis. Here we discuss the treatment of a patient with comorbid mesangioproliferative glomerulonephritis and alveolar echinococcus, behaving like a tumor, using albendazole since there was no possibility of surgery. This is the first ever such case report.

AGN STORM: A Leap Forward In Reverberation Mapping

NASA Astrophysics Data System (ADS)

Dalla Bontà, Elena; AGN STORM Team

2016-10-01

Reverberation mapping is a tomographic technique that can be used to determine the structure and kinematics of the broad- line emitting region at the center of active galactic nuclei. By-products of these investigations are the masses of the central black holes and information about the structure of the accretion disk. I will show some of the most recent results from the AGN Space Telescope and Optical Reverberation Mapping (AGN STORM) project, which was built around 180 daily observations of the bright Seyfert 1 galaxy NGC 5548 with the Cosmic Origins Spectrograph on Hubble Space Telescope. AGN STORM included observations made with Swift, XMM, and several ground-based telescopes, including the 1.22-m telescope at Asiago Observatory. Elena Dalla Bonta` on behalf of the AGN STORM Team.

BAT AGN Spectroscopic Survey - III. An Observed Link Between AGN Eddington Ratio and Narrow-Emission-Line Ratios

NASA Technical Reports Server (NTRS)

Oh, Kyuseok; Schawinski, Kevin; Koss, Michael; Trakhtenbrot, Benny; Lamperti, Isabella; Ricci, Claudio; Mushotzky, Richard; Veilleux, Sylvain; Berney, Simon; Crenshaw, D. Michael;

The fraction of AGNs in major merger galaxies and its luminosity dependence

NASA Astrophysics Data System (ADS)

Weigel, Anna K.; Schawinski, Kevin; Treister, Ezequiel; Trakhtenbrot, Benny; Sanders, David B.

2018-05-01

We use a phenomenological model which connects the galaxy and active galactic nucleus (AGN) populations to investigate the process of AGNs triggering through major galaxy mergers at z ˜ 0. The model uses stellar mass functions as input and allows the prediction of AGN luminosity functions based on assumed Eddington ratio distribution functions (ERDFs). We show that the number of AGNs hosted by merger galaxies relative to the total number of AGNs increases as a function of AGN luminosity. This is due to more massive galaxies being more likely to undergo a merger and does not require the assumption that mergers lead to higher Eddington ratios than secular processes. Our qualitative analysis also shows that to match the observations, the probability of a merger galaxy hosting an AGN and accreting at a given Eddington value has to be increased by a factor ˜10 relative to the general AGN population. An additional significant increase of the fraction of high Eddington ratio AGNs among merger host galaxies leads to inconsistency with the observed X-ray luminosity function. Physically our results imply that, compared to the general galaxy population, the AGN fraction among merger galaxies is ˜10 times higher. On average, merger triggering does however not lead to significantly higher Eddington ratios.

Host Galaxy Properties of SWIFT Hard X-ray Selected AGN

NASA Astrophysics Data System (ADS)

Koss, Michael; Mushotzky, R.; Veilleux, S.; Winter, L.

2010-01-01

Surveys of AGN taken in the optical, UV, and soft X-rays miss an important population of obscured AGN only visible in the hard X-rays and mid-IR wavelengths. The SWIFT BAT survey in the hard X-ray range (14-195 keV) has provided a uniquely unbiased sample of 258 AGN unaffected by galactic or circumnuclear absorption. Optical imaging of this unbiased sample provides a new opportunity to understand how the environments of the host galaxies are linked to AGN. In 2008, we observed 110 of these targets at Kitt Peak with the 2.1m in the SDSS ugriz bands over 17 nights. Using these observations and SDSS data we review the relationships between color, morphology, merger activity, star formation, and AGN luminosity.

S100A8/A9 (Calprotectin) Is Critical for Development of Glomerulonephritis and Promotes Inflammatory Leukocyte–Renal Cell Interactions

PubMed Central

Pepper, Ruth J.; Wang, Hsu-Han; Rajakaruna, Gayathri K.; Papakrivopoulou, Eugenia; Vogl, Thomas; Pusey, Charles D.; Cook, H. Terence; Salama, Alan D.

2015-01-01

Glomerulonephritis is a common cause of end-stage renal disease. Infiltrating leukocytes interacting with renal cells play a critical role during the initiation and progression of glomerulonephritis, but the exact mechanisms are not clearly defined. By using the murine model of nephrotoxic nephritis, we investigated the role of S100A8/A9 [myeloid-related protein (MRP) 8/14, calprotectin] in promoting glomerulonephritis. In nephrotoxic nephritis, wild-type (WT) mice with glomerulonephritis have elevated serum levels of S100A8/A9, whereas mice deficient in MRP14 (S100a9−/−), and hence S100A8/A9, are significantly protected from disease. By using bone marrow transplants, we showed that MRP14 deficiency is required in both the hemopoietic and intrinsic cells for the protective effect. In vitro, both the WT bone marrow–derived macrophages and renal mesangial cells stimulated with S100A8/A9 secrete IL-6, CXCL1, and tumor necrosis factor α; however, Mrp14−/− cells exhibit significantly blunted proinflammatory responses. The interaction of WT bone marrow–derived macrophages with renal microvascular endothelial cells results in increased levels of monocyte chemotactic protein 1, IL-8, and IL-6 cytokines, which is attenuated in Mrp14−/− bone marrow–derived macrophages. Data shows that S100A8/A9 plays a critical role during glomerulonephritis, exerting and amplifying autocrine and paracrine proinflammatory effects on bone marrow–derived macrophages, renal endothelial cells, and mesangial cells. Therefore, complete S100A8/A9 blockade may be a new therapeutic target in glomerulonephritis. PMID:25759267

Testing AGN unification via inference from large catalogs

NASA Astrophysics Data System (ADS)

Nikutta, Robert; Ivezic, Zeljko; Elitzur, Moshe; Nenkova, Maia

2018-01-01

Source orientation and clumpiness of the central dust are the main factors in AGN classification. Type-1 QSOs are easy to observe and large samples are available (e.g. in SDSS), but obscured type-2 AGN are dimmer and redder as our line of sight is more obscured, making it difficult to obtain a complete sample. WISE has found up to a million QSOs. With only 4 bands and a relatively small aperture the analysis of individual sources is challenging, but the large sample allows inference of bulk properties at a very significant level.CLUMPY (www.clumpy.org) is arguably the most popular database of AGN torus SEDs. We model the ensemble properties of the entire WISE AGN content using regularized linear regression, with orientation-dependent CLUMPY color-color-magnitude (CCM) tracks as basis functions. We can reproduce the observed number counts per CCM bin with percent-level accuracy, and simultaneously infer the probability distributions of all torus parameters, redshifts, additional SED components, and identify type-1/2 AGN populations through their IR properties alone. We increase the statistical power of our AGN unification tests even further, by adding other datasets as axes in the regression problem. To this end, we make use of the NOAO Data Lab (datalab.noao.edu), which hosts several high-level large datasets and provides very powerful tools for handling large data, e.g. cross-matched catalogs, fast remote queries, etc.

Mini-Survey of SDSS OIII AGN with Swift

NASA Technical Reports Server (NTRS)

Angelina, Lorella; George, Ian

2007-01-01

There is a common wisdom that every massive galaxy has a massive block hole. However, most of these objects either are not radiating or until recently have been very difficult to detect. The Sloan Digital Sky Survey (SDSS) data, based on the [OIII] line indicate that perhaps up to 20% of all galaxies may be classified as AGN a surprising result that must be checked with independent data. X-ray surveys have revealed that hard X-ray selected AGN show a strong luminosity dependent evolution and their luminosity function (LF) shows a dramatic break towards low Lx (at all z). This is seen for all types of AGN, but is stronger for the broad-line objects. In sharp contrast, the local LF of (optically-selected samples) shows no such break and no differences between narrow and broad-line objects. Assuming both hard X-ray and [OIII] emission are fair indicators of AGN activity, it is important to understand this discrepancy. We present here the results of a mini-survey done with Swift on a selected sample of SDSS selected AGN. The objects have been sampled at different L([OIII]) to check the relation with the Lx observed with Swift.

AGN Variability: Probing Black Hole Accretion

NASA Astrophysics Data System (ADS)

Moreno, Jackeline; O'Brien, Jack; Vogeley, Michael S.; Richards, Gordon T.; Kasliwal, Vishal P.

2017-01-01

We combine the long temporal baseline of Sloan Digital Sky Survey (SDSS) for quasars in Stripe 82 with the high precision photometry of the Kepler/K2 Satellite to study the physics of optical variability in the accretion disk and supermassive black hole engine. We model the lightcurves directly as Continuous-time Auto Regressive Moving Average processes (C-ARMA) with the Kali analysis package (Kasliwal et al. 2016). These models are extremely robust to irregular sampling and can capture aperiodic variability structure on various timescales. We also estimate the power spectral density and structure function of both the model family and the data. A Green's function kernel may also be estimated for the resulting C-ARMA parameter fit, which may be interpreted as the response to driving impulses such as hotspots in the accretion disk. We also examine available spectra for our AGN sample to relate observed and modelled behavior to spectral properties. The objective of this work is twofold: to explore the proper physical interpretation of different families of C-ARMA models applied to AGN optical flux variability and to relate empirical characteristic timescales of our AGN sample to physical theory or to properties estimated from spectra or simulations like the disk viscosity and temperature. We find that AGN with strong variability features on timescales resolved by K2 are well modelled by a low order C-ARMA family while K2 lightcurves with weak amplitude variability are dominated by outliers and measurement errors which force higher order model fits. This work explores a novel approach to combining SDSS and K2 data sets and presents recovered characteristic timescales of AGN variability.

Imaging AGN Feedback in NGC 3393 with CHEERS

NASA Astrophysics Data System (ADS)

Maksym, W. Peter; Fabbiano, Giuseppina; Elvis, Martin; Karovska, Margarita; Paggi, Alessandro; Wang, Junfeng; Storchi-Bergmann, Thaisa

2016-01-01

The CHandra Extended Emission-line Region Survey (CHEERS) is the 'ultimate' resolution X-ray imaging survey of nearby far-IR selected AGN. By comparing deep Chandra observations with complementary HST and radio data, we investigate the morphology of the extended narrow-line region on scales of <100 pc. We present new results on the gas surrounding the compton-thick AGN NGC 3393. The luminous extended narrow-line X-ray emission from this gas allows us to study the role and extent of AGN feedback as sub-kpc jets interact with the surrounding ISM.

Imaging AGN Feedback in NGC 3393 with CHEERS

NASA Astrophysics Data System (ADS)

Paggi, Alessandro; Maksym, W. Peter; Fabbiano, Giuseppina; Elvis, Martin; Karovska, Margarita; Wang, Junfeng; Storchi-Bergmann, Thaisa

2016-04-01

The CHandra Extended Emission-line Region Survey (CHEERS) is the 'ultimate' resolution X-ray imaging survey of nearby far-IR selected AGN. By comparing deep Chandra observations with complementary HST and radio data, we investigate the morphology of the extended narrow-line region on scales of <100 pc. We present new results on the gas surrounding the compton-thick AGN NGC 3393. The luminous extended narrow-line X-ray emission from this gas allows us to study the role and extent of AGN feedback as sub-kpc jets interact with the surrounding ISM.

Spectral-luminosity evolution of active galactic nuclei (AGN)

NASA Technical Reports Server (NTRS)

Leiter, Darryl; Boldt, Elihu

1992-01-01

The origin of the cosmic X-ray and gamma-ray backgrounds is explained via the mechanism of AGN spectral-luminosity evolution. The spectral evolution of precursor active galaxies into AGN, and Newton-Raphson input and output parameters are discussed.

Combined optical coherence tomography and optical coherence elastography for glomerulonephritis classification

NASA Astrophysics Data System (ADS)

Liu, Chih-Hao; Du, Yong; Singh, Manmohan; Wu, Chen; Han, Zhaolong; Li, Jiasong; Mohammadzai, Qais; Raghunathan, Raksha; Hsu, Thomas; Noorani, Shezaan; Chang, Anthony; Mohan, Chandra; Larin, Kirill V.

2016-03-01

Acute Glomerulonephritis caused by anti-glomerular basement membrane disease has a high mortality due to delayed diagnosis. Thus, an accurate and early diagnosis is critical for preserving renal function. Currently, blood, urine, and tissue-based diagnoses can be time consuming, while ultrasound and CT imaging have relatively low spatial resolution. Optical coherence tomography (OCT) is a noninvasive imaging technique that provides superior spatial resolution (micron scale) as compared to ultrasound and CT. Pathological changes in tissue properties can be detected based on the optical metrics analyzed from the OCT signal, such as optical attenuation and speckle variance. Moreover, OCT does not rely on ionizing radiation as with CT imaging. In addition to structural changes, the elasticity of the kidney can significantly change due to nephritis. In this work, we utilized OCT to detect the difference in tissue properties between healthy and nephritic murine kidneys. Although OCT imaging could identify the diseased tissue, classification accuracy using only optical metrics was clinically inadequate. By combining optical metrics with elasticity, the classification accuracy improved from 76% to 95%. These results show that OCT combined with OCE can be potentially useful for nephritis detection.

A model for AGN variability on multiple time-scales

NASA Astrophysics Data System (ADS)

Sartori, Lia F.; Schawinski, Kevin; Trakhtenbrot, Benny; Caplar, Neven; Treister, Ezequiel; Koss, Michael J.; Urry, C. Megan; Zhang, C. E.

2018-05-01

We present a framework to link and describe active galactic nuclei (AGN) variability on a wide range of time-scales, from days to billions of years. In particular, we concentrate on the AGN variability features related to changes in black hole fuelling and accretion rate. In our framework, the variability features observed in different AGN at different time-scales may be explained as realisations of the same underlying statistical properties. In this context, we propose a model to simulate the evolution of AGN light curves with time based on the probability density function (PDF) and power spectral density (PSD) of the Eddington ratio (L/LEdd) distribution. Motivated by general galaxy population properties, we propose that the PDF may be inspired by the L/LEdd distribution function (ERDF), and that a single (or limited number of) ERDF+PSD set may explain all observed variability features. After outlining the framework and the model, we compile a set of variability measurements in terms of structure function (SF) and magnitude difference. We then combine the variability measurements on a SF plot ranging from days to Gyr. The proposed framework enables constraints on the underlying PSD and the ability to link AGN variability on different time-scales, therefore providing new insights into AGN variability and black hole growth phenomena.

Mini-Survey Of SDSS of [OIII] AGN With Swift

NASA Technical Reports Server (NTRS)

Angelini, L.; George, I. M.; Hill, J.; Padgett, C. A.; Mushotzky, R. F.

2008-01-01

The number of AGN and their luminosity distribution are crucial parameters for our understanding of the AGN phenomenon. Recent work (e.g. Ferrarese and Merritt 2000) strongly suggests every massive galaxy has a central black hole. However, most of these objects either are not radiating or have been very difficult to detect. We are now in the era of large surveys, and the luminosity function (LF) of AGN has been estimated in various ways. In the X-ray band, Chandra and XMM surveys (e.g., Barger et al. 2005; Hasinger, et al. 2005) have revealed that the LF of Hard X-ray selected AGN shows a strong luminosity-dependent evolution with a dramatic break towards low L(x) (at al z). This is seen for all types of AGN, but is stronger for the broad-line objects (e.g., Steffen et al. 2004). In sharp contrast, the local LF of optically-selected samples shows no such break and no differences between narrow and broad-line objects (Hao et al. 2005). If, as been suggested, hard X-ray and optical emission line can both be fair indicators of AGN activity, it is important to first understand how reliable these characteristics are if we hope to understand the apparent discrepancy in the LFs.

Radio AGN in the local universe: unification, triggering and evolution

NASA Astrophysics Data System (ADS)

Tadhunter, Clive

2016-06-01

Associated with one of the most important forms of active galactic nucleus (AGN) feedback, and showing a strong preference for giant elliptical host galaxies, radio AGN (L_{1.4 GHz} > 10^{24} W Hz^{-1}) are a key sub-class of the overall AGN population. Recently their study has benefitted dramatically from the availability of high-quality data covering the X-ray to far-IR wavelength range obtained with the current generation of ground- and space-based telescope facilities. Reflecting this progress, here I review our current state of understanding of the population of radio AGN at low and intermediate redshifts (z < 0.7), concentrating on their nuclear AGN and host galaxy properties, and covering three interlocking themes: the classification of radio AGN and its interpretation; the triggering and fuelling of the jet and AGN activity; and the evolution of the host galaxies. I show that much of the observed diversity in the AGN properties of radio AGN can be explained in terms of a combination of orientation/anisotropy, mass accretion rate, and variability effects. The detailed morphologies of the host galaxies are consistent with the triggering of strong-line radio galaxies (SLRG) in galaxy mergers. However, the star formation properties and cool ISM contents suggest that the triggering mergers are relatively minor in terms of their gas masses in most cases, and would not lead to major growth of the supermassive black holes and stellar bulges; therefore, apart from a minority (<20 %) that show evidence for higher star formation rates and more massive cool ISM reservoirs, the SLRG represent late-time re-triggering of activity in mature giant elliptical galaxies. In contrast, the host and environmental properties of weak-line radio galaxies (WLRG) with Fanaroff-Riley class I radio morphologies are consistent with more gradual fuelling of the activity via gas accretion at low rates onto the supermassive black holes.

Ultra-fast outflows (aka UFOs) from AGNs and QSOs

NASA Astrophysics Data System (ADS)

Cappi, M.; Tombesi, F.; Giustini, M.

During the last decade, strong observational evidence has been accumulated for the existence of massive, high velocity winds/outflows (aka Ultra Fast Outflows, UFOs) in nearby AGNs and in more distant quasars. Here we briefly review some of the most recent developments in this field and discuss the relevance of UFOs for both understanding the physics of accretion disk winds in AGNs, and for quantifying the global amount of AGN feedback on the surrounding medium.

A Chandra-Swift View of Point Sources in Hickson Compact Groups: High AGN Fraction but a Dearth of Strong AGNs

NASA Technical Reports Server (NTRS)

Tzanavaris, P.; Gallagher, S. C.; Hornschemeier, A. E.; Fedotov, K.; Eracleous, M.; Brandt, W. N.; Desjardins, T. D.; Charlton, J. C.; Gronwall, C.

2014-01-01

We present Chandra X-ray point source catalogs for 9 Hickson Compact Groups (HCGs, 37 galaxies) at distances of 34-89 Mpc. We perform detailed X-ray point source detection and photometry and interpret the point source population by means of simulated hardness ratios. We thus estimate X-ray luminosities (L(sub x)) for all sources, most of which are too weak for reliable spectral fitting. For all sources, we provide catalogs with counts, count rates, power-law indices (gamma), hardness ratios, and L(sub X), in the full (0.5-8.0 keV), soft (0.5-2.0 keV), and hard (2.0-8.0 keV) bands. We use optical emission-line ratios from the literature to re-classify 24 galaxies as star-forming, accreting onto a supermassive black hole (AGNs), transition objects, or low-ionization nuclear emission regions. Two-thirds of our galaxies have nuclear X-ray sources with Swift/UVOT counterparts. Two nuclei have L(sub X),0.5-8.0 keV > 10(exp 42) erg s-1, are strong multi-wavelength active galactic nuclei (AGNs), and follow the known alpha OX-?L? (nearUV) correlation for strong AGNs. Otherwise, most nuclei are X-ray faint, consistent with either a low-luminosity AGN or a nuclear X-ray binary population, and fall in the 'non-AGN locus' in alpha OX-?L? (nearUV) space, which also hosts other normal galaxies. Our results suggest that HCG X-ray nuclei in high specific star formation rate spiral galaxies are likely dominated by star formation, while those with low specific star formation rates in earlier types likely harbor a weak AGN. The AGN fraction in HCG galaxies with MR (is) less than -20 and L(sub X),0.5-8.0 keV (is) greater than 10(exp 41) erg s-1 is 0.08+0.35 -0.01, somewhat higher than the 5% fraction in galaxy clusters.

Evidence for a mass-dependent AGN Eddington ratio distribution via the flat relationship between SFR and AGN luminosity

NASA Astrophysics Data System (ADS)

Bernhard, E.; Mullaney, J. R.; Aird, J.; Hickox, R. C.; Jones, M. L.; Stanley, F.; Grimmett, L. P.; Daddi, E.

2018-05-01

The lack of a strong correlation between AGN X-ray luminosity (LX; a proxy for AGN power) and the star formation rate (SFR) of their host galaxies has recently been attributed to stochastic AGN variability. Studies using population synthesis models have incorporated this by assuming a broad, universal (i.e. does not depend on the host galaxy properties) probability distribution for AGN specific X-ray luminosities (i.e. the ratio of LX to host stellar mass; a common proxy for Eddington ratio). However, recent studies have demonstrated that this universal Eddington ratio distribution fails to reproduce the observed X-ray luminosity functions beyond z ˜ 1.2. Furthermore, empirical studies have recently shown that the Eddington ratio distribution may instead depend upon host galaxy properties, such as SFR and/or stellar mass. To investigate this further, we develop a population synthesis model in which the Eddington ratio distribution is different for star-forming and quiescent host galaxies. We show that, although this model is able to reproduce the observed X-ray luminosity functions out to z ˜ 2, it fails to simultaneously reproduce the observed flat relationship between SFR and X-ray luminosity. We can solve this, however, by incorporating a mass dependency in the AGN Eddington ratio distribution for star-forming host galaxies. Overall, our models indicate that a relative suppression of low Eddington ratios (λEdd ≲ 0.1) in lower mass galaxies (M* ≲ 1010 - 11 M⊙) is required to reproduce both the observed X-ray luminosity functions and the observed flat SFR/X-ray relationship.

Active galactic nuclei from He II: a more complete census of AGN in SDSS galaxies yields a new population of low-luminosity AGN in highly star-forming galaxies

NASA Astrophysics Data System (ADS)

Bär, Rudolf E.; Weigel, Anna K.; Sartori, Lia F.; Oh, Kyuseok; Koss, Michael; Schawinski, Kevin

2017-04-01

In order to perform a more complete census of active galactic nuclei (AGN) in the local Universe, we investigate the use of the He II λ4685 emission line diagnostic diagram by Shirazi & Brinchmann (2012) in addition to the standard methods based on other optical emission lines. The He II-based diagnostics is more sensitive to AGN ionization in the presence of strong star formation than conventional line diagnostics. We survey a magnitude-limited sample of 63 915 galaxies from the Sloan Digital Sky Survey Data Release 7 at 0.02 < z < 0.05 and use both the conventional BPT emission line diagnostic diagrams, as well as the He II diagram to identify AGN. In this sample, 1075 galaxies are selected as AGN using the BPT diagram, while additional 234 galaxies are identified as AGN using the He II diagnostic diagram, representing a 22 per cent increase of AGN in the parent galaxy sample. We explore the host galaxy properties of these new He II-selected AGN candidates and find that they are most common in star-forming galaxies on the blue cloud and on the main sequence where ionization from star formation is most likely to mask AGN emission in the BPT lines. We note in particular a high He II AGN fraction in galaxies above the high-mass end of the main sequence where quenching is expected to occur. We use archival Chandra observations to confirm the AGN nature of candidates selected through He II-based diagnostic. Finally, we discuss how this technique can help inform galaxy/black hole coevolution scenarios.

Star-forming Galaxies as AGN Imposters? A Theoretical Investigation of the Mid-infrared Colors of AGNs and Extreme Starbursts

NASA Astrophysics Data System (ADS)

Satyapal, Shobita; Abel, Nicholas P.; Secrest, Nathan J.

2018-05-01

We conduct for the first time a theoretical investigation of the mid-infrared spectral energy distribution (SED) produced by dust heated by an active galactic nucleus (AGN) and an extreme starburst. These models employ an integrated modeling approach using photoionization and stellar population synthesis models in which both the line and emergent continuum is predicted from gas exposed to the ionizing radiation from a young starburst and an AGN. In this work, we focus on the infrared colors from the Wide-field Infrared Survey Explorer, predicting the dependence of the colors on the input radiation field, the interstellar medium conditions, the obscuring column, and the metallicity. We find that an extreme starburst can mimic an AGN in two band mid-infrared color cuts employed in the literature. However, the three-band color cuts employed in the literature require starbursts with extremely high ionization parameters or gas densities. We show that the extreme mid-infrared colors seen in some blue compact dwarf galaxies are not due to metallicity but rather a combination of high ionization parameters and high column densities. Based on our theoretical calculations, we present a theoretical mid-infrared color cut that will exclude even the most extreme starburst that we have modeled in this work. The theoretical AGN demarcation region presented here can be used to identify elusive AGN candidates for future follow-up studies with the James Webb Space Telescope. The full suite of simulated SEDs are available online.

Spectrum of Renal and Urinary Tract Diseases in Kashmiri Children.

PubMed

Ashraf, Mohd; Kumar, Virender; Bano, Rifat Ara; Wani, Khursheed Ahmed; Ahmed, Javed; Ahmed, Kaisar

2016-06-01

Definite paucity of data pertaining to spectrum of renal and urinary tract diseases in our state and in various parts of India forms the basis of this study. Available data has emphasized more on specific clinical syndromes and chronic renal diseases rather than over all spectrums of renal and urinary tract diseases, that too in adult population. The present study a retrospective analysis, forms one of the basic data of paediatric nephrology and urology related disorders in our state. Retrospective analysis of the case records of all the hospitalized patients with renal and urinary tract diseases between 2012 and 2013 were performed. Case records were analysed and categorized into various groups like; Urinary Tract Infections (UTI), Acute Kidney Injury (AKI), Acute Glomerulonephritis (AGN), Nephrotic Syndrome (NS), haematuria, Polycystic Kidney Disease (PCKD), Posterior Urethral Valve (PUV), Vesicoureteric Reflux (VUR), Chronic Kidney Disease (CKD), Congenital Anomalies of Kidney and Urinary Iract (CAKUT) and others. These groups were divided into subgroups to get more insight about the pattern of these diseases. Out of 28114 patients hospitalized between 2012 and 2013 years, 447 (232 males and 215 females) patients were diagnosed of renal and urinary tract diseases which forms 1.58% the total admitted patients. Among these patients 32.9% (147/447) were diagnosed Acute Kidney Injury (AKI); 24.1% (108/447): Urinary Tract Infection (UTI); 9.6% (43/447): Acute Glomerulonephritis (AGN); 5.6% (25/447): bilateral hydronephrosis with UTI; 4.47% (20/447): nephrotic syndrome (NS); 3.5% (16/447): haematuria; and 4% (18/447) were having CAKUT (Congenital Anomalies Of Kidney And Urinary Tract). In addition to this there were 17 cases of Renal Tubular Acidosis (RTA), 3 cases of Barter syndrome and one case of Liddle syndrome. A substantial number of children are hospitalized with renal and urinary tract diseases with delayed ages of presentation, which at times have suffered

Monitoring AGNs with Hbeta Asymmetry with the Wyoming Infra-Red Observatory

NASA Astrophysics Data System (ADS)

Brotherton, Michael S.; Du, Pu; Wang, Jian-Min; Wang, Kai; Huang, Zhengpeng; Hu, Chen; Li, Yan-rong; Kasper, David H.; Chick, William T.; Nguyen, My L.; Maithil, Jaya; Hand, Derek; Bai, Jin-Ming; Ho, Luis

2018-06-01

We present preliminary results from two seasons of reverberation mapping of AGNs using the optical longslit spectrograph on the 2.3 meter WIRO telescope. The majority of the sample is part of our "Monitoring AGNs with Hbeta Asymmetry" project, also known as MAHA, which targets rarer AGNs with extremely asymmetric profiles that may provide new insights into the full diversity of size and structure of the broad-line region (BLR). Our hundreds of nights of telescope time provide dozens of epochs of spectra for approximately two dozen objects. Notably we find that many AGNs with broader asymmetric Hbeta emission lines possess time lags significantly shorter than expected for their luminosity in comparison to the majority of AGNs reverberation mapped.

A complete hard X-ray selected sample of local, luminous AGNs

NASA Astrophysics Data System (ADS)

Burtscher, Leonard; Davies, Ric; Lin, Ming-yi; Orban de Xivry, Gilles; Rosario, David

2016-08-01

Choosing a very well defined sample is essential for studying the AGN phenomenon. Only the most luminous AGNs can be expected to require a coherent feeding mechanism to sustain their activity and since host galaxy properties and AGN activity are essentially uncorrelated, nuclear scales must be resolved in order to shed light on the feeding mechanisms of AGNs. For these reasons we are compiling a sample of the most powerful, local AGNs. In this talk we present our on-going programme to observe a complete volume limited sample of nearby active galaxies selected by their 14-195 keV luminosity, and outline its rationale for studying the mechanisms regulating gas inflow and outflow.

Remnant radio-loud AGN in the Herschel-ATLAS field

NASA Astrophysics Data System (ADS)

Mahatma, V. H.; Hardcastle, M. J.; Williams, W. L.; Brienza, M.; Brüggen, M.; Croston, J. H.; Gurkan, G.; Harwood, J. J.; Kunert-Bajraszewska, M.; Morganti, R.; Röttgering, H. J. A.; Shimwell, T. W.; Tasse, C.

2018-04-01

Only a small fraction of observed active galactic nuclei (AGN) display large-scale radio emission associated with jets, yet these radio-loud AGN have become increasingly important in models of galaxy evolution. In determining the dynamics and energetics of the radio sources over cosmic time, a key question concerns what happens when their jets switch off. The resulting `remnant' radio-loud AGN have been surprisingly evasive in past radio surveys, and therefore statistical information on the population of radio-loud AGN in their dying phase is limited. In this paper, with the recent developments of Low-Frequency Array (LOFAR) and the Very Large Array, we are able to provide a systematically selected sample of remnant radio-loud AGN in the Herschel-ATLAS field. Using a simple core-detection method, we constrain the upper limit on the fraction of remnants in our radio-loud AGN sample to 9 per cent, implying that the extended lobe emission fades rapidly once the core/jets turn off. We also find that our remnant sample has a wide range of spectral indices (-1.5≤slant α ^{1400}_{150}≤slant -0.5), confirming that the lobes of some remnants may possess flat spectra at low frequencies just as active sources do. We suggest that, even with the unprecedented sensitivity of LOFAR, our sample may still only contain the youngest of the remnant population.

AGN coronal emission models - I. The predicted radio emission

NASA Astrophysics Data System (ADS)

Raginski, I.; Laor, Ari

2016-06-01

Accretion discs in active galactic nucleus (AGN) may be associated with coronal gas, as suggested by their X-ray emission. Stellar coronal emission includes radio emission, and AGN corona may also be a significant source for radio emission in radio quiet (RQ) AGN. We calculate the coronal properties required to produce the observed radio emission in RQ AGN, either from synchrotron emission of power-law (PL) electrons, or from cyclosynchrotron emission of hot mildly relativistic thermal electrons. We find that a flat spectrum, as observed in about half of RQ AGN, can be produced by corona with a disc or a spherical configuration, which extends from the innermost regions out to a pc scale. A spectral break to an optically thin power-law emission is expected around 300-1000 GHz, as the innermost corona becomes optically thin. In the case of thermal electrons, a sharp spectral cut-off is expected above the break. The position of the break can be measured with very long baseline interferometry observations, which exclude the cold dust emission, and it can be used to probe the properties of the innermost corona. Assuming equipartition of the coronal thermal energy density, the PL electrons energy density, and the magnetic field, we find that the energy density in a disc corona should scale as ˜R-1.3, to get a flat spectrum. In the spherical case the energy density scales as ˜R-2, and is ˜4 × 10-4 of the AGN radiation energy density. In Paper II we derive additional constraints on the coronal parameters from the Gudel-Benz relation, Lradio/LX-ray ˜ 10- 5, which RQ AGN follow.

Focal segmental necrotizing glomerulonephritis in rheumatoid arthritis.

PubMed

Harper, L; Cockwell, P; Howie, A J; Michael, J; Richards, N T; Savage, C O; Wheeler, D C; Bacon, P A; Adu, D

1997-02-01

We report ten patients with rheumatoid arthritis (RA) who developed a focal segmental necrotizing glomerulonephritis (FSNGN) and extracapillary proliferation typical of vasculitic glomerulonephritis. Five patients also had extrarenal vasculitis. Renal presentation was with renal impairment (n = 9) (median creatinine 726 mumol/l, range 230-1592 mumol/l), microscopic haematuria (n = 8) and proteinuria (n = 10). Nine patients were seropositive for rheumatoid factor and nine had bone erosions. Serum from four of five patients tested by indirect immunofluorescence was positive for antineutrophil cytoplasmic antibody (ANCA) with perinuclear staining. Only three patients had penicillamine or gold therapy. Treatment was with prednisolone and cyclophosphamide (six patients, two of whom were also plasma-exchanged), prednisolone and azathioprine (two patients) and prednisolone alone (two patients). There was a marked improvement in renal function in eight patients. Two patients with dialysis-dependent renal failure recovered renal function, although in one patient this was transient and she required further dialysis 4 months later. Two other patients progressed to dialysis at 3 months and 1 year respectively. Four patients died, one remains dialysis-dependent, and four continue to have good renal function at 5 year follow-up (median creatinine 148.5 mumol/l, range 120-193 mumol/l). One patient was lost to follow-up at 5 years. FSNGN should be considered in all patients with RA and renal impairment, proteinuria and/or microscopic haematuria. This diagnosis appears to be more likely in patients with clinical extrarenal vasculitis, bone erosions or who are seropositive. In these cases, an urgent renal biopsy is indicated.

Suppression of Rapidly Progressive Mouse Glomerulonephritis with the Non-Steroidal Mineralocorticoid Receptor Antagonist BR-4628.

PubMed

Ma, Frank Y; Han, Yingjie; Nikolic-Paterson, David J; Kolkhof, Peter; Tesch, Greg H

2015-01-01

Steroidal mineralocorticoid receptor antagonists (MRAs) are effective in the treatment of kidney disease; however, the side effect of hyperkalaemia, particularly in the context of renal impairment, is a major limitation to their clinical use. Recently developed non-steroidal MRAs have distinct characteristics suggesting that they may be superior to steroidal MRAs. Therefore, we explored the benefits of a non-steroidal MRA in a model of rapidly progressive glomerulonephritis. Accelerated anti-glomerular basement membrane (GBM) glomerulonephritis was induced in groups of C57BL/6J mice which received no treatment, vehicle or a non-steroidal MRA (BR-4628, 5mg/kg/bid) from day 0 until being killed on day 15 of disease. Mice were examined for renal injury. Mice with anti-GBM glomerulonephritis which received no treatment or vehicle developed similar disease with severe albuminuria, impaired renal function, glomerular tuft damage and crescents in 40% of glomeruli. In comparison, mice which received BR-4628 displayed similar albuminuria, but had improved renal function, reduced severity of glomerular tuft lesions and a 50% reduction in crescents. The protection seen in BR-4628 treated mice was associated with a marked reduction in glomerular macrophages and T-cells and reduced kidney gene expression of proinflammatory (CCL2, TNF-α, IFN-γ) and profibrotic molecules (collagen I, fibronectin). In addition, treatment with BR-4626 did not cause hyperkalaemia or increase urine Na+/K+ excretion (a marker of tubular dysfunction). The non-steroidal MRA (BR-4628) provided substantial suppression of mouse crescentic glomerulonephritis without causing tubular dysfunction. This finding warrants further investigation of non-steroidal MRAs as a therapy for inflammatory kidney diseases.

Monthly plasmapheresis for systemic lupus erythematosus with diffuse proliferative glomerulonephritis: a pilot study

PubMed Central

Clark, William F.; Lindsay, Robert M.; Cattran, Daniel C.; Chodirker, William B.; Barnes, Colin C.; Linton, Adam L.

1981-01-01

Twelve patients with systemic lupus erythematosus and biopsy-proved diffuse proliferative glomerulonephritis were randomly allocated to a control group (to continue receiving conventional therapy only) or to a plasmapheresis group (to receive conventional therapy along with one 4-I plasma exchange a month). The six patients treated with plasmapheresis had better preservation of renal function, reduced disease activity, fewer admissions to hospital and less need for steroid and immunosuppressive therapy than the six control patients. The patients treated with plasmapheresis also showed evidence of reduced immunologic activity and had no side effects attributable to the plasma exchange. These results suggest that monthly plasma exchange should be assessed in a controlled randomized trial as a possible therapeutic adjunct in patients with systemic lupus erythematosus and diffuse proliferative glomerulonephritis. PMID:7272867

The joint fit of the BHMF and ERDF for the BAT AGN Sample

NASA Astrophysics Data System (ADS)

Weigel, Anna K.; Koss, Michael; Ricci, Claudio; Trakhtenbrot, Benny; Oh, Kyuseok; Schawinski, Kevin; Lamperti, Isabella

2018-01-01

A natural product of an AGN survey is the AGN luminosity function. This statistical measure describes the distribution of directly measurable AGN luminosities. Intrinsically, the shape of the luminosity function depends on the distribution of black hole masses and Eddington ratios. To constrain these fundamental AGN properties, the luminosity function thus has to be disentangled into the black hole mass and Eddington ratio distribution function. The BASS survey is unique as it allows such a joint fit for a large number of local AGN, is unbiased in terms of obscuration in the X-rays and provides black hole masses for type-1 and type-2 AGN. The black hole mass function at z ~ 0 represents an essential baseline for simulations and black hole growth models. The normalization of the Eddington ratio distribution function directly constrains the AGN fraction. Together, the BASS AGN luminosity, black hole mass and Eddington ratio distribution functions thus provide a complete picture of the local black hole population.

Compton thick AGN in Chandra sureys

NASA Astrophysics Data System (ADS)

Brightman, Murray; Nandra, Kirpal

2014-07-01

We present the results from the X-ray spectral analysis of active galactic nuclei (AGN) in the Chandra Deep Field-South, AEGIS-XD and Chandra-COSMOS surveys, focussing on the identification and characterisation of the most heavily obscured, Compton thick (CT, N H > 104 cm-2) sources. Our sample is comprised of 3088 X-ray selected sources, which has a high rate of redshift completeness (97%). The aim is to produce the largest and cleanest uniform sample of these sources from the data as possible. We identify these sources through X-ray spectral fitting, utilising torus spectral models designed for heavily obscured AGN which self consistently include the spectral signatures of heavy absorption, being Compton scattering, photoelectric absorption and iron Kα fluorescence. We identify a total of 163 CT AGN covering an intrinsic 2-10 keV X-ray luminosity range of 102 -3 × 105 erg s-1 and from z = 0.1-7.

A hospital-based study to evaluate the incidence pattern of group A streptococcal throat infections from different age group patients.

PubMed

Ray, Dipanwita; Banerjee, Surajita; Bhattacharya, Sujata; Sinha, Sukanta; Bandyopadhyay, Debasis; Ghosal, Chaitry; Gupta, Siddhartha; Majumdar, Pallav Kumar; Saha, Somnath; Gupta, Soma; Bhattacharya, Basudev

2010-02-01

Streptococcus pyogenes(group A) is a major pathogen capable of causing a wide range of diseases in different age group of people. In this study 100 patients were selected who presented with the complaint of sore throat. All the patients were divided in four age groups. Streptococcus pyogenes colonies were confirmed on the basis of beta-haemolysis, bacitracin sensitivity test, and latex agglutination test for group A. Out of a total of 100 samples, 42 were confirmed as group A streptococcus. From this study, it has been observed that all age groups, with maximum occurrence in 5-15 years age group, were suffering from group A streptococcal pharyngitis. Therefore every case of sore throat especially affecting children should be investigated to detect the causative agent for initiation of proper therapy so that the more serious outcome like acute rheumatic fever (ARF) and acute glomerulonephritis (AGN) can be prevented.

Host Galaxy Properties of the Swift BAT Ultra Hard X-Ray Selected AGN

NASA Technical Reports Server (NTRS)

Koss, Michael; Mushotzky, Richard; Veilleux, Sylvain; Winter, Lisa M.; Baumgartner, Wayne; Tueller, Jack; Gehrels, Neil; Valencic, Lynne

2011-01-01

We have assembled the largest sample of ultra hard X-ray selected (14-195 keV) AGN with host galaxy optical data to date, with 185 nearby (z<0.05), moderate luminosity AGN from the Swift Burst Alert Telescope (BAT) sample. The BAT AGN host galaxies have intermediate optical colors (u -- r and g -- r) that are bluer than a comparison sample of inactive galaxies and optically selected AGN from the Sloan Digital Sky Survey (SDSS) which are chosen to have the same stellar mass. Based on morphological classifications from the RC3 and the Galaxy Zoo, the bluer colors of BAT AGN are mainly due to a higher fraction of mergers and massive spirals than in the comparison samples. BAT AGN in massive galaxies (log Stellar Mass >10.5) have a 5 to 10 times higher rate of spiral morphologies than in SDSS AGN or inactive galaxies. We also see enhanced far-IR emission in BAT AGN suggestive of higher levels of star formation compared to the comparison samples. BAT AGN are preferentially found in the most massive host galaxies with high concentration indexes indicative of large bulge-to-disk ratios and large supermassive black holes. The narrow-line (NL) BAT AGN have similar intrinsic luminosities as the SDSS NL Seyferts based on measurements of [O III] Lambda 5007. There is also a correlation between the stellar mass and X-ray emission. The BAT AGN in mergers have bluer colors and greater ultra hard X-ray emission compared to the BAT sample as whole. In agreement with the Unified Model of AGN, and the relatively unbiased nature of the BAT sources, the host galaxy colors and morphologies are independent of measures of obscuration such as X-ray column density or Seyfert type. The high fraction of massive spiral galaxies and galaxy mergers in BAT AGN suggest that host galaxy morphology is related to the activation and fueling of local AGN.

Do some AGN lack X-ray emission?

NASA Astrophysics Data System (ADS)

Simmonds, C.; Bauer, F. E.; Thuan, T. X.; Izotov, Y. I.; Stern, D.; Harrison, F. A.

2016-12-01

Context. Intermediate-mass black holes (IMBHs) are thought to be the seeds of early supermassive black holes (SMBHs). While ≳100 IMBH and small SMBH candidates have been identified in recent years, few have been robustly confirmed to date, leaving their number density in considerable doubt. Placing firmer constraints both on the methods used to identify and confirm IMBHs/SMBHs, as well as characterizing the range of host environments that IMBHs/SMBHs likely inhabit is therefore of considerable interest and importance. Additionally, finding significant numbers of IMBHs in metal-poor systems would be particularly intriguing, since such systems may represent local analogs of primordial galaxies, and therefore could provide clues of early accretion processes. Aims: Here we study in detail several candidate active galactic nuclei (AGN) found in metal-poor hosts. Methods: We utilize new X-ray and optical observations to characterize these metal-poor AGN candidates and compare them against known AGN luminosity relations and well-characterized IMBH/SMBH samples. Results: Despite having clear broad optical emission lines that are long-lived (≳10-13 yr), these candidate AGN appear to lack associated strong X-ray and hard UV emission, lying at least 1-2 dex off the known AGN correlations. If they are IMBHs/SMBHs, our constraints imply that they either are not actively accreting, their accretion disks are fully obscured along our line-of-sight, or their accretion disks are not producing characteristic high energy emission. Alternatively, if they are not AGN, then their luminous broad emission lines imply production by extreme stellar processes. The latter would have profound implications on the applicability of broad lines for mass estimates of massive black holes. The reduced spectra (FITS files) are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/596/A64

Can Radio Emission From Luminous Obscured AGN Blow Kpc-scale Ionized Outflows?

NASA Astrophysics Data System (ADS)

Goulding, Andy

2017-09-01

We propose joint VLA radio and Chandra X-ray to observe 4 AGN selected from the SDSS-BOSS and the Hyper Suprime-Cam surveys that present spectacular extended outflowing [O III] regions, reaching up to 50kpc in diameter. Our proposed observations allow us to study the mechanical and kinematical output of the AGN through radio and X-ray observations, measure the fraction of the AGN bolometric luminosity that is transferred to the outflow, and to determine the morphology and spectral index (by producing high-res continuum maps) of the radio emission that may be co-spatial with the extended ionized AGN outflow. In turn, our study will determine what role the AGN plays in producing extended outflows, and hence, provide an in-depth understanding of the physical drivers of AGN feedback.

[Acute renal pain as an adverse reaction of the rabies immunization].

PubMed

Lalosević, Dusan

2009-01-01

HRIG is the best preparate in rabies prophylaxis, and it's considered that optimal dose is 20 international units per kilogram and must not been reduced or overdosed. HRIG have to be injected infiltrative around bite wounds, and if after that remains a part of the dose, it has to be given in gluteal muscle. Application only in gluteus is vitium artis. At one patient immunized against rabies has occured acute bilateral renal pain and fever at time of immunization against rabies, and because of that vaccination must been stopped after the 3rd dose of vaccine. Patient was a 26-year-old female without significant pre-existing disease, bitten by stray dog. After the start of immunization, because the wrong direction, she received about 2.5 more amount of human rabies immunoglobuline (HRIG) then is recommended on declaration at etiquette of ampoule, and only in gluteus in quantity of 10.5 ml. Glomerulonephritis after rabies vaccination until now was described just once by Singhal et al. in 1981. year. Acute renal pain, after rabies vaccine, which aggravated after repeated vaccine doses in our patient who received overdosed HRIG, may be explained by immunopathological mechanism, rather with formation of circulating immune complexes, their precipitation on the glomerular basement membrane and developing glomerulonephritis. Low weight soluble molecular immune complexes formed when antigen is in excess, as in case after repeated doses of rabies vaccine, circulate and precipitate on glomerular membrane and causes glomerulonephritis. As contribution to this explanation, is that symptoms as renal pain disappeared after interrupting vaccination protocol in our patient.

Massive Molecular Outflows and Evidence for AGN Feedback from CO Observations

DTIC Science & Technology

2013-11-13

J. Thomson Avenue, Cambridge CB3 0HE, UK e-mail: c.cicone@mrao.cam.ac.uk 2 Kavli Institute for Cosmology , University of Cambridge, Madingley Road...molecular outflow as a function of AGN luminosity. Theoretical models of AGN feed- back and cosmological simulations predict a coupling efficiency between AGN

Mid-infrared Flux Variability in an Awakening AGN

NASA Astrophysics Data System (ADS)

Yeh, Sherry

We propose FORCAST spectroscopic observations between 8 um to 40 um near the nucleus of NGC 660. NGC 660 underwent an AGN outburst 6 years ago, which is an ideal case for studying AGN astrophysics in a rather quiecent system. However, this rare event has not yet been monitored. Our immidiate goal is to verify the MIR spectroscipic variabilitiy in NGC 660, and to study the AGN effects on dust destruction and ISM. We will compare the FORCAST spectra with the Spitzer IRS spectra (taken before the AGN outburst), including dust continuum, PAH emission, and high- and low-ionization emission lines. FORCAST's slit width is a close match to the IRS slit width, allowing a direct comparison of the spectra between FORCAST and IRS. Our single-slit Subaru COMICS spectrum taken after the outburst shows significantly weakened PAH emission and dust continuum, suggesting dust destruction. However, it is difficult to draw robust intepretations due to systematic uncertainties in the Subaru data. If dust destruction is confirmed in the post-outburst FORCAST observaitons, we will evaluate the energy budget using the MIR line ratio diagnostics, with archival X-ray and radio data. We will then propose cadence observations of MGC 660's nucleus to monitor the MIR flux variability, and employ the reverberation mapping technique to study NGC 660's AGN.

The energetics of AGN radiation pressure-driven outflows

NASA Astrophysics Data System (ADS)

Ishibashi, W.; Fabian, A. C.; Maiolino, R.

2018-05-01

The increasing observational evidence of galactic outflows is considered as a sign of active galactic nucleus (AGN) feedback in action. However, the physical mechanism responsible for driving the observed outflows remains unclear, and whether it is due to momentum, energy, or radiation is still a matter of debate. The observed outflow energetics, in particular the large measured values of the momentum ratio (\\dot{p}/(L/c) ˜ 10) and energy ratio (\\dot{E}_k/L ˜ 0.05), seems to favour the energy-driving mechanism; and most observational works have focused their comparison with wind energy-driven models. Here, we show that AGN radiation pressure on dust can adequately reproduce the observed outflow energetics (mass outflow rate, momentum flux, and kinetic power), as well as the scalings with luminosity, provided that the effects of radiation trapping are properly taken into account. In particular, we predict a sublinear scaling for the mass outflow rate (\\dot{M} ∝ L^{1/2}) and a superlinear scaling for the kinetic power (\\dot{E}_k ∝ L^{3/2}), in agreement with the observational scaling relations reported in the most recent compilation of AGN outflow data. We conclude that AGN radiative feedback can account for the global outflow energetics, at least equally well as the wind energy-driving mechanism, and therefore both physical models should be considered in the interpretation of future AGN outflow observations.

Inverse Compton X-ray signature of AGN feedback

NASA Astrophysics Data System (ADS)

Bourne, Martin A.; Nayakshin, Sergei

2013-12-01

Bright AGN frequently show ultrafast outflows (UFOs) with outflow velocities vout ˜ 0.1c. These outflows may be the source of AGN feedback on their host galaxies sought by galaxy formation modellers. The exact effect of the outflows on the ambient galaxy gas strongly depends on whether the shocked UFOs cool rapidly or not. This in turn depends on whether the shocked electrons share the same temperature as ions (one-temperature regime, 1T) or decouple (2T), as has been recently suggested. Here we calculate the inverse Compton spectrum emitted by such shocks, finding a broad feature potentially detectable either in mid-to-high energy X-rays (1T case) or only in the soft X-rays (2T). We argue that current observations of AGN do not seem to show evidence for the 1T component. The limits on the 2T emission are far weaker, and in fact it is possible that the observed soft X-ray excess of AGN is partially or fully due to the 2T shock emission. This suggests that UFOs are in the energy-driven regime outside the central few pc, and must pump considerable amounts of not only momentum but also energy into the ambient gas. We encourage X-ray observers to look for the inverse Compton components calculated here in order to constrain AGN feedback models further.

Uncovering extreme AGN variability in serendipitous X-ray source surveys

NASA Astrophysics Data System (ADS)

Moran, Edward C.; Garcia Soto, Aylin; LaMassa, Stephanie; Urry, Meg

2018-01-01

Constraints on the duty cycle and duration of accretion episodes in active galactic nuclei (AGNs) are vital for establishing how most AGNs are fueled, which is essential for a complete picture of black hole/galaxy co-evolution. Perhaps the best handle we have on these activity parameters is provided by AGNs that have displayed dramatic changes in their bolometric luminosities and, in some cases, spectroscopic classifications. Given that X-ray emission is directly linked to black-hole accretion, X-ray surveys should provide a straightforward means of identifying AGNs that have undergone dramatic changes in their accretion states. However, it appears that such events are very rare, so wide-area surveys separated in time by many years are needed to maximize discovery rates. We have cross-correlated the Einstein IPC Two-Sigma Catalog with the ROSAT All-Sky Survey Faint Source Catalog to identify a sample of soft X-ray sources that varied by factors ranging from 7 to more than 100 over a ten year timescale. When possible, we have constructed long-term X-ray light curves for the sources by combining the Einstein and RASS fluxes with those obtained from serendipitous pointed observations by ROSAT, Chandra,XMM, and Swift. Optical follow-up observations indicate that many of the extremely variable sources in our sample are indeed radio-quiet AGNs. Interestingly, the majority of objects that dimmed between ~1980 and ~1990 are still (or are again) broad-line AGNs rather than“changing-look” candidates that have more subtle AGN signatures in their spectra — despite the fact that none of the sources examined thus far has returned to its highest observed luminosity. Future X-ray observations will provide the opportunity to characterize the X-ray behavior of these anonymous, extreme AGNs over a four decade span.

A MODEL FOR TYPE 2 CORONAL LINE FOREST (CLiF) AGNs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Glidden, Ana; Rose, Marvin; Elvis, Martin

2016-06-10

We present a model for the classification of Coronal Line Forest Active Galactic Nuclei (CLiF AGNs). CLiF AGNs are of special interest due to their remarkably large number of emission lines, especially forbidden high-ionization lines (FHILs). Rose et al. suggest that their emission is dominated by reflection from the inner wall of the obscuring region rather than direct emission from the accretion disk. This makes CLiF AGNs laboratories to test AGN-torus models. Modeling an AGN as an accreting supermassive black hole surrounded by a cylinder of dust and gas, we show a relationship between the viewing angle and the revealedmore » area of the inner wall. From the revealed area, we can determine the amount of FHIL emission at various angles. We calculate the strength of [Fe vii] λ 6087 emission for a number of intermediate angles (30°, 40°, and 50°) and compare the results with the luminosity of the observed emission line from six known CLiF AGNs. We find that there is good agreement between our model and the observational results. The model also enables us to determine the relationship between the type 2:type 1 AGN fraction vs the ratio of torus height to radius, h / r .« less

Host Galaxy Properties Of The Swift Bat Hard X-ray Survey Of Agn

NASA Astrophysics Data System (ADS)

Koss, Michael; Mushotzky, R.; Veilleux, S.; Winter, L.

2010-03-01

Surveys of AGN taken in the optical, UV, and soft X-rays miss an important population of obscured AGN only visible in the hard X-rays and mid-IR wavelengths. The SWIFT BAT survey in the hard X-ray range (14-195 keV) has provided a uniquely unbiased sample of AGN unaffected by galactic or circumnuclear absorption. Optical imaging of this unbiased sample provides a new opportunity to understand how the environments of the host galaxies are linked to AGN. In 2008, we observed 90 of these targets at Kitt Peak with the 2.1m in the SDSS ugriz bands over 17 nights. Using these observations and SDSS data we review the relationships between color, morphology, merger activity, stellar mass, star formation, and AGN luminosity for a sample of 145 AGN Hard X-ray Selected AGN.

Unveiling the AGN activity in multiple SMBH systems observed with XMM-Newton

NASA Astrophysics Data System (ADS)

De Rosa, A.

2017-10-01

In this talk we will present results from the MAGNA (Multiple AGN Activity) project focused on the detection and study of multiple supermassive black hole systems. We investigate the physical properties (accretion rate and local environment) of multiple AGN candidates in interacting systems with respect to isolated sources with the goal to understand the mechanisms that trigger AGN activity in different stages of galaxy mergers. We present the study performed with SDSS and XMM data sets of 4 AGN pairs at separations of 20-70 kpc. XMM data allowed us to detect and characterize the AGN in all systems, by measuring the accretion and absorption properties of the sources. In each system at least one object is highly obscured, possibly Compton-thick, in agreement with the hypothesis that galaxy encounters are effective in driving gas inflow. One system however manifests the opposite behaviour showing a pair composed from an unobscured type 1 AGN and a Compton Thick AGN. The talk will reflect on broader implications of these findings.

Large 21-cm signals from AGN-dominated reionization

NASA Astrophysics Data System (ADS)

Kulkarni, Girish; Choudhury, Tirthankar Roy; Puchwein, Ewald; Haehnelt, Martin G.

2017-08-01

We present predictions for the spatial distribution of 21-cm brightness temperature fluctuations from high-dynamic-range simulations for active galactic nucleus (AGN)-dominated reionization histories that have been tested against available Lyα and cosmic microwave background (CMB) data. We model AGNs by extrapolating the observed Mbh - σ relation to high redshifts and assign them ionizing emissivities consistent with recent UV luminosity function measurements. We assess the observability of the predicted spatial 21-cm fluctuations in the late stages of reionization in the limit in which the hydrogen 21-cm spin temperature is significantly larger than the CMB temperature. Our AGN-dominated reionization histories increase the variance of the 21-cm emission by a factor of up to 10 compared to similar reionization histories dominated by faint galaxies, to values close to 100 mK2 at scales accessible to experiments (k ≲ 1 cMpc-1 h). This is lower than the sensitivity reached by ongoing experiments only by a factor of about 2 or less. When reionization is dominated by AGNs, the 21-cm power spectrum is enhanced on all scales due to the enhanced bias of the clustering of the more massive haloes and the peak in the large scale 21-cm power is strongly enhanced and moved to larger scales due to bigger characteristic bubble sizes. AGN-dominated reionization should be easily detectable by Low Frequency Array (and later Hydrogen Epoch of Reionization Array and Phase 1 of the Square Kilometre Array) at their design sensitivity, assuming successful foreground subtraction and instrument calibration. Conversely, these could become the first non-trivial reionization scenarios to be ruled out by 21-cm experiments, thereby constraining the contribution of AGNs to reionization.

Compton thick AGN in the NuSTAR era

NASA Astrophysics Data System (ADS)

Marchesi, Stefano; Ajello, Marco; Marcotulli, Lea; Comastri, Andrea

2017-08-01

The recent launch of the Nuclear Spectroscopic Telescope Array (NuSTAR), the first telescope with focusing optics at >10 keV, represented a major breakthrough in the study of obscured active galactic nuclei (AGN). In this talk, I present the results of the 0.3-100 keV spectral analysis of the 30 Compton thick (CT-; i.e., those sources having column density NH>1E24 cm-2) AGN detected within z~0.1 in the BAT 100-month survey with available NuSTAR data. Particularly, I will focus on how adding NuSTAR data to the 0.3-10 keV information helps to characterize the CT-AGN population, significantly improving the measurements of important X-ray spectral parameters such as the photon index, the intrinsic absorption, the intensity of the Iron K alpha line at 6.4 keV and the obscuring torus opening angle. Finally, I will discuss the role of these objects in the context of obscured AGN accretion physics, and their contribution to the cosmic X-ray background.

The AGN Luminosity Fraction in Galaxy Mergers

NASA Astrophysics Data System (ADS)

Dietrich, Jeremy; Weiner, Aaron; Ashby, Matthew; Martinez-Galarza, Juan Rafael; Smith, Howard Alan

2017-01-01

Galaxy mergers are key events in galaxy evolution, generally triggering massive starbursts and AGNs. However, in these chaotic systems, it is not yet known what fraction each of these two mechanisms contributes to the total luminosity. Here we measure and model spectral energy distributions (SEDs) using the Code for Investigating Galaxy Emission (CIGALE) in up to 33 broad bands from the UV to the far-IR for 23 IR-luminous galaxies to estimate the fraction of the bolometric IR luminosity that can be attributed to the AGN. The galaxies are split nearly evenly into two subsamples: late-stage mergers, found in the IRAS Revised Bright Galaxy Sample or Faint Source Catalog, and early-stage mergers found in the Spitzer Interacting Galaxy Sample. We find that the AGN contribution to the total IR luminosity varies greatly from system to system, from 0% up to ~90%, but is substantially greater in the later-stage and brighter mergers. This is consistent with what is known about galaxy evolution and the triggering of AGNs.The SAO REU program is funded in part by the National Science Foundation REU and Department of Defense ASSURE programs under NSF Grant no. 1262851, and by the Smithsonian Institution.

Imprints of the large-scale structure on AGN formation and evolution

NASA Astrophysics Data System (ADS)

Porqueres, Natàlia; Jasche, Jens; Enßlin, Torsten A.; Lavaux, Guilhem

2018-04-01

Black hole masses are found to correlate with several global properties of their host galaxies, suggesting that black holes and galaxies have an intertwined evolution and that active galactic nuclei (AGN) have a significant impact on galaxy evolution. Since the large-scale environment can also affect AGN, this work studies how their formation and properties depend on the environment. We have used a reconstructed three-dimensional high-resolution density field obtained from a Bayesian large-scale structure reconstruction method applied to the 2M++ galaxy sample. A web-type classification relying on the shear tensor is used to identify different structures on the cosmic web, defining voids, sheets, filaments, and clusters. We confirm that the environmental density affects the AGN formation and their properties. We found that the AGN abundance is equivalent to the galaxy abundance, indicating that active and inactive galaxies reside in similar dark matter halos. However, occurrence rates are different for each spectral type and accretion rate. These differences are consistent with the AGN evolutionary sequence suggested by previous authors, Seyferts and Transition objects transforming into low-ionization nuclear emission line regions (LINERs), the weaker counterpart of Seyferts. We conclude that AGN properties depend on the environmental density more than on the web-type. More powerful starbursts and younger stellar populations are found in high densities, where interactions and mergers are more likely. AGN hosts show smaller masses in clusters for Seyferts and Transition objects, which might be due to gas stripping. In voids, the AGN population is dominated by the most massive galaxy hosts.

Hypercat - Hypercube of Clumpy AGN Tori

NASA Astrophysics Data System (ADS)

Nikutta, Robert; Lopez-Rodriguez, Enrique; Ichikawa, Kohei; Levenson, Nancy; Packham, Christopher C.

2017-06-01

Dusty tori surrounding the central engines of Active Galactic Nuclei (AGN) are required by the Unification Paradigm, and are supported by many observations, e.g. variable nuclear absorber (sometimes Compton-thick) in X-rays, reverberation mapping in optical/UV, hot dust emission and SED shapes in NIR/MIR, molecular and cool-dust tori observed with ALMA in sub-mm.While models of AGN torus SEDs have been developed and utilized for a long time, the study of the resolved emission morphology (brightness maps) has so far been under-appreciated, presumably because resolved observations of the central parsec in AGN are only possible very recently. Currently, only NIR+MIR interferometry is capable of resolving the nuclear dust emission (but not of producing images, until MATISSE comes online). Furthermore, MIR interferometry has delivered also puzzling results, e.g. that in some resolved sources the light emanates preferentially from polar directions above the "torus" system, and not from the equatorial plane, where most of the dust is located.We are preparing the release of a panchromatic, fully interpolable hypercube of brightness maps and projected dust images for a large number of CLUMPY torus models (Nenkova+2008), that will help facilitate studies of resolved AGN emission and dust morphologies. Together with the cube we will release a comprehensive set of open-source tools (Python) that will enable researches to work efficiently with this large hypercube:* easy sub-cube selection + memory-mapping (mitigating the too-big-for-RAM problem)* multi-dim image interpolation (get an image at any wavelength & model parameter combination)* simulation of observations with telescopes (compute/provide + apply a PSF) and interferometers (get visibilities)* analyze images with respect to the power contained at all scales and orientations (via 2D steerable wavelets), addressing the seemingly puzzling results mentioned aboveA series of papers is in preparation, aiming at solving the

Using WISE to Find Obscured AGN Activity in SDSS Mergers and Interactions

NASA Astrophysics Data System (ADS)

Weston, Madalyn; McIntosh, Daniel H.; Her, Xiachang; Rigby, Jane R.

2015-01-01

In simulations, major encounters between gas-rich galaxies are predicted to drive gas to the centers of interacting and merging systems triggering new star formation (SF) and fueling an active galactic nucleus (AGN). Depending on the rate of SF, large amounts of obscuring dust can make detection of merger-induced activity difficult and may be at the heart of the ongoing merger-AGN connection debate. To provide better constraints on the importance of obscured AGNs, we use data from the Wide-field Infrared Survey Explorer (WISE) for a comprehensive sample of over 1000 major galaxy interactions and ongoing mergers visually selected from the SDSS with Mstar>1e10 Msun and 0.01 < z < 0.08. We examine the [3.4]-[4.6] versus [4.6]-[12] micron color-color plane and find that most interactions and mergers have the same colors as normal (non-interacting and non-merging) galaxies, which define a narrow [3.4]-[4.6] micron locus and span a wide range in [4.6]-[12] micron colors from spectroscopically quiescent (blue, no dust) to galaxies with SF emission (dust-reddened). We find that 2-6% of mergers (and 2-3% of interactions) have unusually red [3.4]-[4.6] micron colors, which are associated with dust-obscured (Type-2) AGNs. We note that mergers (interactions) are 4-15 (3-8) times more likely to host a buried AGN than normal galaxies. We also find that optical emission-line AGNs (Seyferts) identified as mergers are 3-7 times more likely to be obscured than non-merging Seyferts. We investigate whether the obscured AGN subset of our sample have unique properties and find that their stellar masses, mass ratios, pair separations, and environments are not statistically different from those of the bulk of mergers and interactions with normal WISE colors. We note that among mergers and interactions with an AGN, the WISE-selected AGN favor higher [OIII] luminosities associated with higher AGN power than their unobscured counterparts. Our findings support an AGN-merger connection.

Morphologies of mid-IR variability-selected AGN host galaxies

NASA Astrophysics Data System (ADS)

Polimera, Mugdha; Sarajedini, Vicki; Ashby, Matthew L. N.; Willner, S. P.; Fazio, Giovanni G.

2018-05-01

We use multi-epoch 3.6 and 4.5 μm data from the Spitzer Extended Deep Survey (SEDS) to probe the AGN population among galaxies to redshifts ˜3 via their mid-IR variability. About 1 per cent of all galaxies in our survey contain varying nuclei, 80 per cent of which are likely to be AGN. Twenty-three per cent of mid-IR variables are also X-ray sources. The mid-IR variables have a slightly greater fraction of weakly disturbed morphologies compared to a control sample of normal galaxies. The increased fraction of weakly distorted hosts becomes more significant when we remove the X-ray emitting AGN, while the frequency of strongly disturbed hosts remains similar to the control galaxy sample. These results suggest that mid-IR variability identifies a unique population of obscured, Compton-thick AGN revealing elevated levels of weak distortion among their host galaxies.

Constraining AGN triggering mechanisms through the clustering analysis of active black holes

NASA Astrophysics Data System (ADS)

Gatti, M.; Shankar, F.; Bouillot, V.; Menci, N.; Lamastra, A.; Hirschmann, M.; Fiore, F.

2016-02-01

The triggering mechanisms for active galactic nuclei (AGN) are still debated. Some of the most popular ones include galaxy interactions (IT) and disc instabilities (DIs). Using an advanced semi-analytic model (SAM) of galaxy formation, coupled to accurate halo occupation distribution modelling, we investigate the imprint left by each separate triggering process on the clustering strength of AGN at small and large scales. Our main results are as follows: (I) DIs, irrespective of their exact implementation in the SAM, tend to fall short in triggering AGN activity in galaxies at the centre of haloes with Mh > 1013.5 h-1 M⊙. On the contrary, the IT scenario predicts abundance of active central galaxies that generally agrees well with observations at every halo mass. (II) The relative number of satellite AGN in DIs at intermediate-to-low luminosities is always significantly higher than in IT models, especially in groups and clusters. The low AGN satellite fraction predicted for the IT scenario might suggest that different feeding modes could simultaneously contribute to the triggering of satellite AGN. (III) Both scenarios are quite degenerate in matching large-scale clustering measurements, suggesting that the sole average bias might not be an effective observational constraint. (IV) Our analysis suggests the presence of both a mild luminosity and a more consistent redshift dependence in the AGN clustering, with AGN inhabiting progressively less massive dark matter haloes as the redshift increases. We also discuss the impact of different observational selection cuts in measuring AGN clustering, including possible discrepancies between optical and X-ray surveys.

2MASS J00423991+3017515: An AGN On The Run?

NASA Astrophysics Data System (ADS)

Hogg, James

2016-09-01

We have discovered a peculiar AGN, 2MASS J00423991+3017515, in a local (z=0.14), disturbed galaxy whose optical spectrum has multiple broad lines that are consistently offset from the narrow line emission and host galaxy absorption by 1530 km/s. The morphology of the host galaxy and spectral properties thus suggest this AGN may be a recoiling supermassive black hole (SMBH). We propose high-resolution X-ray imaging and spectral follow-ups with the ACIS camera on Chandra to determine if the source of the kinematically-offset broad line emission is also spatially offset from the nucleus of the host galaxy. If a single, spatially offset AGN is detected, this source will be strongest candidate for a recoiling AGN candidate discovered to date.

Modeling optical and UV polarization of AGNs. IV. Polarization timing

NASA Astrophysics Data System (ADS)

Rojas Lobos, P. A.; Goosmann, R. W.; Marin, F.; Savić, D.

2018-03-01

Context. Optical observations cannot resolve the structure of active galactic nuclei (AGN), and a unified model for AGN was inferred mostly from indirect methods, such as spectroscopy and variability studies. Optical reverberation mapping allowed us to constrain the spatial dimension of the broad emission line region and thereby to measure the mass of supermassive black holes. Recently, reverberation was also applied to the polarized signal emerging from different AGN components. In principle, this should allow us to measure the spatial dimensions of the sub-parsec reprocessing media. Aim. We conduct numerical modeling of polarization reverberation and provide theoretical predictions for the polarization time lag induced by different AGN components. The model parameters are adjusted to the observational appearance of the Seyfert 1 galaxy NGC 4151. Methods: We modeled scattering-induced polarization and tested different geometries for the circumnuclear dust component. Our tests included the effects of clumpiness and different dust prescriptions. To further extend the model, we also explored the effects of additional ionized winds stretched along the polar direction, and of an equatorial scattering ring that is responsible for the polarization angle observed in pole-on AGN. The simulations were run using a time-dependent version of the STOKES code. Results: Our modeling confirms the previously found polarization characteristics as a function of the observer`s viewing angle. When the dust adopts a flared-disk geometry, the lags reveal a clear difference between type 1 and type 2 AGN. This distinction is less clear for a torus geometry where the time lag is more sensitive to the geometry and optical depth of the inner surface layers of the funnel. The presence of a scattering equatorial ring and ionized outflows increased the recorded polarization time lags, and the polar outflows smooths out dependence on viewing angle, especially for the higher optical depth of the

Disentangling Dominance: Obscured AGN Activity versus Star Formation in BPT-Composites

NASA Astrophysics Data System (ADS)

Trouille, Laura

2011-11-01

Approximately 20% of SDSS emission-line galaxies (ELG) lie in the BPT-comp regime, between the Kauffmann et al. (2003) empirically determined SF-dominated regime and the Kewley et al. (2001) theoretically predicted AGN-dominated regime. BPT-AGN, on the other hand, make up only 11% of the ELG population. Whether to include the significant number of BPT-comp in samples of AGN or samples of star-forming galaxies is an open question and has important implications for galaxy evolution studies, metallicity studies, etc. Using a large pectroscopic sample of GOODS-N and LH galaxies with deep Chandra imaging, we perform an X-ray stacking analysis of BPT-comp. We find the stacked signal to be X-ray hard. This X-ray hardness can be indicative of obscured AGN activity or the presence of HMXBs associated with ongoing star formation. In order to distinguish between these scenarios, we perform an IR stacking analysis using Spitzer 24 micron data. The stacked BPT-comp lies well above the expected value for L_x/L_IR for pure star-forming galaxies; similarly for the X-ray detected BPT-comp. We also find that the BPT-comp lie in the AGN-dominated regime of our new TBT diagnostic, which uses [NeIII]/[OII] versus rest-frame g-z colour to identify AGN and star forming galaxies out to z=1.4. [NeIII], which has a higher ionisation potential than other commonly used forbidden emission lines, appears to foster a more reliable selection of AGN-dominated galaxies. These findings suggest that both the X-ray and optical signal in BPT-comp are dominated by obscured or low accretion rate AGN activity rather than star formation. This is in contrast to claims by previous optical emission-line studies that the signal in BPT-comp is dominated by star-formation activity. Therefore, we recommend that groups carefully consider the impact of excluding or including BPT-comp on the interpretation of their results. For example, for studies involving determining the bolometric contribution from AGN activity

The study of AGN variability using extended emission line regions

NASA Astrophysics Data System (ADS)

Sartori, Lia

2018-01-01

The study of AGN variability on different timescales can provide important information about black hole accretion physics, as well as the black hole – host galaxy interaction and coevolution. The discovery of an extended AGN photoionised cloud associated with the nearby galaxy IC 2497, the so-called “Hanny’s Voorwerp” (HV), provided us with a laboratory to study AGN variability over 100 kyr timescales. HV was illuminated by a strong quasar, but the quasar in IC 2497 dropped in luminosity in the last 200 kyrs. Because of its recent change we can now explore the host galaxy unimpeded by the presence of a quasar dominating the observations. On the other hand, the photoionised cloud preserves the echoes of its past activity. Citizen scientists taking part in the Galaxy Zoo project assembled a sample of low-redshift galaxies showing AGN photoionised clouds similar to HV. I will show how these objects can help us understand what happens when a quasar changes in luminosity and accretion state, and ultimately what is the physics driving AGN variability.

Uncovering Heavily Obscured AGN with WISE and NuSTAR

NASA Astrophysics Data System (ADS)

Hickox, Ryan C.; Carroll, Christopher M.; Yan, Wei; DiPompeo, Michael A.; Hainline, Kevin N.; NuSTAR Obscured AGN Team

2018-01-01

Supermassive black holes gain their mass through accretion as active galactic nuclei (AGN), but it is now clear that a large fraction of this growth is "hidden" behind large columns of gas and dust. Of particular interest are Compton-thick (CT) AGN, with columns NH > 1024 cm-2, that have been difficult to identify using optical or soft X-ray surveys. We will present two studies of heavily obscured AGN that aim to uncover more of the full population of "hidden" growing black holes: (1) Analysis of the spectral energy distributions of millions of galaxies with photometry from WISE (mid-IR), UKIDSS (near-IR), and SDSS (optical), that uncovers large populations of weak or heavily buried AGN, and (2) NuSTAR observations of a sample of candidate highly obscured AGN, selected from WISE and SDSS photometry,and confirmed using SALT and Keck spectroscopy. The NuSTAR data reveal the existence of powerful CT quasars with extremely large columns NH > 1025 cm-2, which may represent a significant fraction of previously hidden black hole growth. This work is supported by NASA grant numbers NNX16AN48G and NNX15AP24G, and the NSF through grant numbers 1515364 and 1554584.

Modeling IR SED of AGN with Spitzer and Herschel data

NASA Astrophysics Data System (ADS)

Feltre, A.

2012-12-01

One of the remaining open issues in the context of the analysis of Active Galactic Nuclei (AGN) is the evidence that nuclear gravitational accretion is often accompanied by a concurrent starburst (SB) activity. What is, in this picture, the role played by the obscur- ing dust around the nucleus and what do the state of the art AGN torus models have to say? Can the IR data provided by Spitzer and Herschel help us in extensively investigate both phenomena and, if so, how and with what limitations? In this paper we present our contribution to the efforts of answering these questions. We show some of the main results coming from a comparative study of various AGN SED modeling approaches, focusing mostly on the much-debated issue about the morphology of the dust distribution in the toroidal structure surrounding the AGN. We found that the properties of dust in AGN as measured by matching observations (be it broad band IR photometry or IR spectra) with models, strongly depend on the choice of the dust distribution. Then, we present the spec- tral energy distribution (SED) fitting procedure we developed, making make the best use of Spitzer and Herschel SPIRE mid- and far-IR observations, to dig into the role played by the possible presence of an AGN on the host galaxy's properties.

Prevention of crescentic glomerulonephritis in SCG/Kj mice by bone marrow transplantation.

PubMed

Cherry; Engelman, R W; Wang, B Y; Kinjoh, K; El-Badri, N S; Good, R A

1998-07-01

Transplantation of MHC-compatible, T-cell-depleted, bone marrow cells has successfully treated autoimmunities, immunodeficiencies, malignancies, and developmental deficiencies of the hematopoietic system. Recombinant inbred SCG/Kj mice develop spontaneous crescentic glomerulonephritis, systemic vasculitis, and a lymphoproliferative disorder early in life. To determine whether the precipitous autoimmune disease of SCG/Kj mice could be treated by bone marrow transplantation, 30 SCG/Kj mice were engrafted with T-cell-depleted, bone marrow (TCDM) from allogeneic, MHC-compatible, autoimmune-resistant C3H/He donors, and 30 SCG/Kj mice served as controls and received TCDM from syngeneic, SCG/Kj donors. A significant survival advantage was evident from SCG/Kj mice engrafted with C3H/He TCDM (p < 0.005), and an 89% extension of median survival compared to recipients of SCG/Kj TCDM. Within 28 weeks post-transplantation, 62% of mice engrafted with SCG/Kj TCDM had died with clinical signs of fatal crescentic glomerulonephritis. This result compared with only 10% of mice engrafted with C3H/He TCDM. Mice engrafted with SCG/Kj TCDM developed significantly greater titers of autoantibodies to ss-DNA, ds-DNA, and myeloperoxidase (ANCA) (p < 0.001), had shorter latencies to the development of, and a greater incidence of proteinuria, hematuria, and peripheral lymphadenopathy, and a greater mean grade of glomerular lesion (p < 0.001), than mice engrafted with C3H/He TCDM. These findings indicate that the genetic defect of the SCG/Kj strain of mice resides within the hematopoietic stem cells and provokes the speculation that bone marrow transplantation might be a useful means of treating progressive crescentic glomerulonephritis in humans.

Are Compton-thick AGNs the Missing Link between Mergers and Black Hole Growth?

NASA Astrophysics Data System (ADS)

Kocevski, Dale D.; Brightman, Murray; Nandra, Kirpal; Koekemoer, Anton M.; Salvato, Mara; Aird, James; Bell, Eric F.; Hsu, Li-Ting; Kartaltepe, Jeyhan S.; Koo, David C.; Lotz, Jennifer M.; McIntosh, Daniel H.; Mozena, Mark; Rosario, David; Trump, Jonathan R.

2015-12-01

We examine the host morphologies of heavily obscured active galactic nuclei (AGNs) at z∼ 1 to test whether obscured super-massive black hole growth at this epoch is preferentially linked to galaxy mergers. Our sample consists of 154 obscured AGNs with {N}{{H}}\\gt {10}23.5 {{cm}}-2 and z\\lt 1.5. Using visual classifications, we compare the morphologies of these AGNs to control samples of moderately obscured (1022 cm{}-2\\lt {N}{{H}}\\lt {10}23.5 {{cm}}-2) and unobscured ({N}{{H}}\\lt {10}22 {{cm}}-2) AGN. These control AGNs have similar redshifts and intrinsic X-ray luminosities to our heavily obscured AGN. We find that heavily obscured AGNs are twice as likely to be hosted by late-type galaxies relative to unobscured AGNs ({65.3}-4.6+4.1% versus {34.5}-2.7+2.9%) and three times as likely to exhibit merger or interaction signatures ({21.5}-3.3+4.2% versus {7.8}-1.3+1.9%). The increased merger fraction is significant at the 3.8σ level. If we exclude all point sources and consider only extended hosts, we find that the correlation between the merger fraction and obscuration is still evident, although at a reduced statistical significance (2.5σ ). The fact that we observe a different disk/spheroid fraction versus obscuration indicates that the viewing angle cannot be the only thing differentiating our three AGN samples, as a simple unification model would suggest. The increased fraction of disturbed morphologies with obscuration supports an evolutionary scenario, in which Compton-thick AGNs are a distinct phase of obscured super-massive black hole (SMBH) growth following a merger/interaction event. Our findings also suggest that some of the merger-triggered SMBH growth predicted by recent AGN fueling models may be hidden among the heavily obscured, Compton-thick population.

AGN are cooler than you think: the intrinsic far-IR emission from QSOs

NASA Astrophysics Data System (ADS)

Symeonidis, M.; Giblin, B. M.; Page, M. J.; Pearson, C.; Bendo, G.; Seymour, N.; Oliver, S. J.

2016-06-01

We present an intrinsic AGN spectral energy distribution (SED) extending from the optical to the submm, derived with a sample of unobscured, optically luminous (νLν,5100 > 1043.5 erg s-1) QSOs at z < 0.18 from the Palomar Green survey. The intrinsic AGN SED was computed by removing the contribution from stars using the 11.3 μm polycyclic aromatic hydrocarbon (PAH) feature in the QSOs' mid-IR spectra; the 1σ uncertainty on the SED ranges between 12 and 45 per cent as a function of wavelength and is a combination of PAH flux measurement errors and the uncertainties related to the conversion between PAH luminosity and star-forming luminosity. Longwards of 20 μm, the shape of the intrinsic AGN SED is independent of the AGN power indicating that our template should be applicable to all systems hosting luminous AGN (νLν, 5100 or L_X(2-10 keV) ≳ 1043.5 erg s-1). We note that for our sample of luminous QSOs, the average AGN emission is at least as high as, and mostly higher than, the total stellar powered emission at all wavelengths from the optical to the submm. This implies that in many galaxies hosting powerful AGN, there is no `safe' broad-band photometric observation (at λ < 1000 μm) which can be used in calculating star formation rates without subtracting the AGN contribution. Roughly, the AGN contribution may be ignored only if the intrinsic AGN luminosity at 5100 AA is at least a factor of 4 smaller than the total infrared luminosity (LIR, 8-1000 μm) of the galaxy. Finally, we examine the implication of our work in statistical studies of star formation in AGN host galaxies.

X-Rays and Infrared Selected AGN

NASA Astrophysics Data System (ADS)

Kirhakos, S. D.; Steiner, J. E.

1990-11-01

RESUMEN. En la busqueda de nucleos activos galacticos (NAG) oscurecidos, seleccionamos una tnuestra de galaxias ernisoras de rayos S infrarrojos, Ia mayoria de las cuales son vistas de perf ii. La 6ptica de la regi6n nuclear de las galaxias seleccionadas revelan que el 76% de ellas muestran lineas de emisi5n La clasificaci6n de los es- pectros de acuerdo a los anchos y a la intensidad de cocientes de lineas muestran que existen 34 NAG, 34 objetos de tipo de transici6n y 34 galaxias de la regi6n con nucleos de tipo regi6n H II. Entre los NAG, 3 son del tipo Seyfert I y las otras son del tipo 2. Sugerimos que los objetos identificados como NAG de llneas angostas son objetos tipo Seyfert I oscurecidos ABSTRACT. Looking for obscured active galactic nuclei (AGN), we selected a sample of infrarediX-rays emitting galaxies, mos"t of which are seen as edge-on. Optical spectroscopy of the nuclear region of the selected galaxies revealed that 76 % of them show emission l 'nes. Classification of the spectra according to the widths and line intensity ratios shows that there are 34 AGN, 34 transition type objects and 43 nuclear HIl-like region galaxies. Among the AGN, three are Seyfert type 1 and the others are type 2 objects. We suggest that the objects identified as narrow line AGN are obscured Seyfert 1. o'L : GALAXIES-ACTIVE - X-RAY S-GENERAL

Mid-infrared Variability of Changing-look AGNs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sheng, Zhenfeng; Wang, Tinggui; Jiang, Ning

2017-09-01

It is known that some active galactic nuclei (AGNs) transit from Type 1 to Type 2 or vice versa. There are two explanations for the so-called changing-look AGNs: one is the dramatic change of the obscuration along the line of sight, and the other is the variation of accretion rate. In this Letter, we report the detection of large amplitude variations in the mid-infrared luminosity during the transitions in 10 changing-look AGNs using the Wide-field Infrared Survey Explorer ( WISE ) and newly released Near-Earth Object WISE Reactivation data. The mid-infrared light curves of 10 objects echo the variability inmore » the optical band with a time lag expected for dust reprocessing. The large variability amplitude is inconsistent with the scenario of varying obscuration, rather it supports the scheme of dramatic change in the accretion rate.« less

A POWERFUL AGN OUTBURST IN RBS 797

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cavagnolo, K. W.; McNamara, B. R.; Wise, M. W.

2011-05-10

Utilizing {approx}50 ks of Chandra X-Ray Observatory imaging, we present an analysis of the intracluster medium (ICM) and cavity system in the galaxy cluster RBS 797. In addition to the two previously known cavities in the cluster core, the new and deeper X-ray image has revealed additional structure associated with the active galactic nucleus (AGN). The surface brightness decrements of the two cavities are unusually large and are consistent with elongated cavities lying close to our line of sight. We estimate a total AGN outburst energy and mean jet power of {approx}(3-6) x 10{sup 60} erg and {approx}(3-6) x 10{supmore » 45} erg s{sup -1}, respectively, depending on the assumed geometrical configuration of the cavities. Thus, RBS 797 is apparently among the most powerful AGN outbursts known in a cluster. The average mass accretion rate needed to power the AGN by accretion alone is {approx}1 M{sub sun} yr{sup -1}. We show that accretion of cold gas onto the AGN at this level is plausible, but that Bondi accretion of the hot atmosphere is probably not. The brightest cluster galaxy (BCG) harbors an unresolved, non-thermal nuclear X-ray source with a bolometric luminosity of {approx}2 x 10{sup 44} erg s{sup -1}. The nuclear emission is probably associated with a rapidly accreting, radiatively inefficient accretion flow. We present tentative evidence that star formation in the BCG is being triggered by the radio jets and suggest that the cavities may be driving weak shocks (M {approx} 1.5) into the ICM, similar to the process in the galaxy cluster MS 0735.6+7421.« less

Morphology of AGN Emission Line Regions in SDSS-IV MaNGA Survey

NASA Astrophysics Data System (ADS)

He, Zhicheng; Sun, Ai-Lei; Zakamska, Nadia L.; Wylezalek, Dominika; Kelly, Michael; Greene, Jenny E.; Rembold, Sandro B.; Riffel, Rogério; Riffel, Rogemar A.

2018-05-01

Extended narrow-line regions (NLRs) around active galactic nuclei (AGN) are shaped by the distribution of gas in the host galaxy and by the geometry of the circumnuclear obscuration, and thus they can be used to test the AGN unification model. In this work, we quantify the morphologies of the narrow-line regions in 308 nearby AGNs (z = 0 - 0.14, Lbol˜1042.4 - 44.1 erg s-1) from the MaNGA survey. Based on the narrow-line region maps, we find that a large fraction (81%) of these AGN have bi-conical NLR morphology. The distribution of their measured opening angles suggests that the intrinsic opening angles of the ionization cones has a mean value of 85-98° with a finite spread of 39-44° (1-σ). Our inferred opening angle distribution implies a number ratio of type I to type II AGN of 1:1.6-2.3, consistent with other measurements of the type I / type II ratio at low AGN luminosities. Combining these measurements with the WISE photometry data, we find that redder mid-IR color (lower effective temperature of dust) corresponds to stronger and narrower photo-ionized bicones. This relation is in agreement with the unification model that suggests that the bi-conical narrow-line regions are shaped by a toroidal dusty structure within a few pc from the AGN. Furthermore, we find a significant alignment between the minor axis of host galaxy disks and AGN ionization cones. Together, these findings suggest that obscuration on both circumnuclear (˜pc) and galactic (˜ kpc) scales are important in shaping and orienting the AGN narrow-line regions.

ACE Inhibition in Anti-Thy1 Glomerulonephritis Limits Proteinuria but Does Not Improve Renal Function and Structural Remodeling

PubMed Central

Westerweel, Peter E.; Joles, Jaap A.; den Ouden, Krista; Goldschmeding, Roel; Rookmaaker, Maarten B.; Verhaar, Marianne C.

2012-01-01

Background/Aims ACE inhibitor (ACE-I) treatment effectively inhibits proteinuria and ameliorates the course of various renal diseases. In experimental glomerulonephritis, however, angiotensin II (AngII) infusion has also been shown to be renoprotective. We evaluated the long-term (28 days) course of anti-Thy1 glomerulonephritis in animals with suppressed AngII formation by ACE-I treatment. Methods Brown Norway rats received perindopril (2.8 mg/kg/day, n = 12), dihydropyridine calcium-antagonist amlodipine (Ca-A; 13 mg/kg/day, n = 6) or were left untreated (n = 14). All animals were monitored for blood pressure, proteinuria, and creatinine clearance after anti-Thy1 injection. Renal histology was assessed at day 7 and 28. Results Systolic blood pressure was equally reduced by ACE-I and Ca-A treatment. AngII suppression prevented development of proteinuria, but did not protect against glomerular microaneurysm formation or reduction in creatinine clearance. After resolution of the microaneurysms, animals with suppressed AngII production showed a modest increase in glomerulosclerosis and vasculopathic thickening of intrarenal vessels. Conclusions In anti-Thy1 glomerulonephritis, suppression of AngII formation does not protect against the induction of glomerular damage and is associated with mild aggravation of adverse renal fibrotic remodeling. Proteinuria, however, is effectively prevented by ACE-I treatment. Ca-A treatment did not affect the course of glomerulonephritis, indicating that ACE-I effects are blood pressure independent. PMID:22479264

UNRAVELLING THE COMPLEX STRUCTURE OF AGN-DRIVEN OUTFLOWS. II. PHOTOIONIZATION AND ENERGETICS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Karouzos, Marios; Woo, Jong-Hak; Bae, Hyun-Jin, E-mail: woo@astro.snu.ac.kr

2016-12-20

Outflows have been shown to be prevalent in galaxies hosting luminous active galactic nuclei (AGNs); they present a physically plausible way to couple the AGN energy output with the interstellar medium of their hosts. Despite their prevalence, accurate characterization of these outflows has been challenging. In the second of a series of papers, we use Gemini Multi-Object Spectrograph integral field unit (IFU) data of six local ( z  < 0.1) and moderate-luminosity Type 2 AGNs to study the ionization properties and energetics of AGN-driven outflows. We find strong evidence connecting the extreme kinematics of the ionized gas to the AGN photoionization.more » The kinematic component related to the AGN-driven outflow is clearly separated from other kinematic components, such as virial motions or rotation, on the velocity and velocity dispersion diagram. Our spatially resolved kinematic analysis reveals that 30 to 90% of the total mass and kinetic energy of the outflow is contained within the central kpc of the galaxy. The spatially integrated mass and kinetic energy of the gas entrained in the outflow correlate well with the AGN bolometric luminosity and results in energy conversion efficiencies between 0.01% and 1%. Intriguingly, we detect ubiquitous signs of ongoing circumnuclear star formation. Their small size, the centrally contained mass and energy, and the universally detected circumnuclear star formation cast doubts on the potency of these AGN-driven outflows as agents of galaxy-scale negative feedback.« less

Fast Ionized X-ray Absorbers in AGNs

NASA Astrophysics Data System (ADS)

Fukumura, K.; Tombesi, F.; Kazanas, D.; Shrader, C.; Behar, E.; Contopoulos, I.

2015-07-01

We present a study of X-ray ionization of MHD accretion-disk wind models in an effort to explain the highly-ionized ultra-fast outflows (UFOs) identified as X-ray absorbers recently detected in various sub-classes of Seyfert AGNs. Our primary focus is to show that magnetically-driven outflows are physically plausible candidates to account for the AGN X-ray spectroscopic observations. We calculate its X-ray ionization and the ensuing X-ray absorption line spectra in comparison with an XXM-Newton/EPIC spectrum of the narrow-line Seyfert AGN, PG 1211+143. We find, through identifying the detected features with Fe Kα transitions, that the absorber has a characteristic ionization parameter of log(xi[erg cm/s]) = 5-6 and a hydrogen-equivalent column density on the order of 1e23 cm-2, outflowing at a sub-relativistic velocity of v/c = 0.1-0.2. The best-fit model favors its radial location at R = 200 Rs (Rs is the Schwarzschild radius), with a disk inner truncation radius at Rt = 30Rs. The overall K-shell feature in data is suggested to be dominated by Fe XXV with very little contribution from Fe XXVI and weakly-ionized iron, which is in a good agreement with a series of earlier analysis of the UFOs in various AGNs including PG 1211+143.

The Incidence of Buried Dual AGN in Advanced Mergers: New results from Chandra

NASA Astrophysics Data System (ADS)

Pfeifle, Ryan William; Satyapal, Shobita; Secrest, Nathan; Gliozzi, Mario; Ricci, Claudio; Ellison, Sara L.; Blecha, Laura; Rothberg, Barry; Constantin, Anca

2018-01-01

Since the vast majority of galaxies contain supermassive black holes (SMBHs) and galaxy interactions trigger nuclear gas accretion, a direct consequence of the hierarchical model of galaxy formation would be the existence of dual active galactic nuclei (AGN). The existence, frequency, and characteristics of such dual AGN have important astrophysical implications on the SMBH mass function, the interplay between SMBHs and the host galaxy, and the M-sigma relation. Despite decades of searching, and strong theoretical reasons for their existence, observationally confirmed cases of dual AGN are extremely rare, and most have been discovered serendipitously. Using the all-sky WISE survey, we identified a population of over one hundred strongly interacting galaxies that display extreme red mid-infrared colors thus far exclusively associated with extragalactic sources possessing powerful AGN. In a recent Chandra, XMM-Newton, and NuSTAR investigation of advanced mergers selected by WISE, we find dual AGN candidates in 8 out of 15 mergers, all of which show no evidence for AGN based on optical spectroscopy. Our results demonstrate that 1) optical studies miss a significant fraction of single and dual AGN in advanced mergers, and 2) mid-infrared pre-selection is extremely effective in identifying dual AGN candidates in late-stage mergers. Our multi-wavelength observations suggest that the buried AGN in these mergers are highly absorbed, with intrinsic column densities in excess of NH > 1024 cm-2, consistent with hydrodynamic simulations.

Broad Band Properties of the BAT Selected AGN

NASA Technical Reports Server (NTRS)

Mushotzky, Richard; Winter, Lisa; Tueller, jack

2008-01-01

We will present the x-ray spectral properties of approximately 150 Burst Alert Telescope (BAT) selected active galactic nuclei (AGN) focusing on the issues of spectral complexity, x-ray absorption and its distribution and that contribution of sources to the x-ray background. If time permits we will also present the nature of the host galaxies of the AGN and their relationship to merger candidates.

Long-Term Variability of AGN at Hard X-Rays

NASA Technical Reports Server (NTRS)

Soldi, S.; Beckmann, V.; Baumgartner W. H.; Ponti, G.; Shrader, C. R.; Lubinski, P.; Krimm, H. A.; Mattana, F.; Tueller, J.

2013-01-01

Variability at all observed wavelengths is a distinctive property of active galactic nuclei (AGN). Hard X-rays provide us with a view of the innermost regions of AGN, mostly unbiased by absorption along the line of sight. Characterizing the intrinsic hard X-ray variability of a large AGN sample and comparing it to the results obtained at lower X-ray energies can significantly contribute to our understanding of the mechanisms underlying the high-energy radiation. Methods. Swift/BAT provides us with the unique opportunity to follow, on time scales of days to years and with a regular sampling, the 14-195 keV emission of the largest AGN sample available up to date for this kind of investigation. As a continuation of an early work on the first 9 months of BAT data, we study the amplitude of the variations, and their dependence on sub-class and on energy, for a sample of 110 radio quiet and radio loud AGN selected from the BAT 58-month survey. About 80 of the AGN in the sample are found to exhibit significant variability on months to years time scales, radio loud sources being the most variable. The amplitude of the variations and their energy dependence are incompatible with variability being driven at hard X-rays by changes of the absorption column density. In general, the variations in the 14-24 and 35-100 keV bands are well correlated, suggesting a common origin of the variability across the BAT energy band. However, radio quiet AGN display on average 10 larger variations at 14-24 keV than at 35-100 keV and a softer-when-brighter behavior for most of the Seyfert galaxies with detectable spectral variability on month time scale. In addition, sources with harder spectra are found to be more variable than softer ones. These properties are generally consistent with a variable power law continuum, in flux and shape, pivoting at energies 50 keV, to which a constant reflection component is superposed. When the same time scales are considered, the timing properties of AGN at

Rituximab for Treatment of Membranoproliferative Glomerulonephritis and C3 Glomerulopathies

PubMed Central

2017-01-01

Membranoproliferative glomerulonephritis (MPGN) is a histological pattern of injury resulting from predominantly subendothelial and mesangial deposition of immunoglobulins or complement factors with subsequent inflammation and proliferation particularly of the glomerular basement membrane. Recent classification of MPGN is based on pathogenesis dividing MPGN into immunoglobulin-associated MPGN and complement-mediated C3 glomerulonephritis (C3GN) and dense deposit disease (DDD). Current guidelines suggest treatment with steroids, cytotoxic agents with or without plasmapheresis only for subjects with progressive disease, that is, nephrotic range proteinuria and decline of renal function. Rituximab, a chimeric B-cell depleting anti-CD20 antibody, has emerged in the last decade as a treatment option for patients with primary glomerular diseases such as minimal change disease, focal-segmental glomerulosclerosis, or idiopathic membranous nephropathy. However, data on the use of rituximab in MPGN, C3GN, and DDD are limited to case reports and retrospective case series. Patients with immunoglobulin-associated and idiopathic MPGN who were treated with rituximab showed partial and complete responses in the majorities of cases. However, rituximab was not effective in few cases of C3GN and DDD. Despite promising results in immunoglobulin-associated and idiopathic MPGN, current evidence on this treatment remains weak, and controlled and prospective data are urgently needed. PMID:28573137

An immune-complex glomerulonephritis of Chinook salmon, Oncorhynchus tshawytscha (Walbaum).

PubMed

Lumsden, J S; Russell, S; Huber, P; Wybourne, B A; Ostland, V E; Minamikawa, M; Ferguson, H W

2008-12-01

Chinook salmon from New Zealand were shown to have a generalized membranous glomerulonephritis that was most severe in large fish. Marked thickening of the glomerular basement membrane was the most consistent lesion, with the presence of an electron-dense deposit beneath the capillary endothelium.Severely affected glomeruli also had expansion of the mesangium and loss of capillaries,synechiae of the visceral and parietal epithelium and mild fibrosis of Bowmans capsule. Chinook salmon from British Columbia, Canada with bacterial kidney disease caused by Renibacterium salmoninarum had similar histological lesions. They also had thickened glomerular basement membranes that were recognized by rabbit antiserum to rainbow trout immunoglobulin. This was true only when frozen sections of kidney were used and not formalin-fixed tissue. An attempt to experimentally produce a glomerulopathy in rainbow trout by repeated immunization with killed R. salmoninarum was not successful. Case records from the Fish Pathology Laboratory at the University of Guelph over a 10-year period revealed that a range of species were diagnosed with glomerulopathies similar to those seen in Chinook salmon. The majority of these cases were determined to have chronic inflammatory disease. This report has identified the presence of immunoglobulin within thickened basement membranes of Chinook salmon with glomerulonephritis and supports the existence of type III hypersensitivity in fish.

Compton Reflection in AGN with Simbol-X

NASA Astrophysics Data System (ADS)

Beckmann, V.; Courvoisier, T. J.-L.; Gehrels, N.; Lubiński, P.; Malzac, J.; Petrucci, P. O.; Shrader, C. R.; Soldi, S.

2009-05-01

AGN exhibit complex hard X-ray spectra. Our current understanding is that the emission is dominated by inverse Compton processes which take place in the corona above the accretion disk, and that absorption and reflection in a distant absorber play a major role. These processes can be directly observed through the shape of the continuum, the Compton reflection hump around 30 keV, and the iron fluorescence line at 6.4 keV. We demonstrate the capabilities of Simbol-X to constrain complex models for cases like MCG-05-23-016, NGC 4151, NGC 2110, and NGC 4051 in short (10 ksec) observations. We compare the simulations with recent observations on these sources by INTEGRAL, Swift and Suzaku. Constraining reflection models for AGN with Simbol-X will help us to get a clear view of the processes and geometry near to the central engine in AGN, and will give insight to which sources are responsible for the Cosmic X-ray background at energies >20 keV.

MOJAVE - XIV. Shapes and opening angles of AGN jets

NASA Astrophysics Data System (ADS)

Pushkarev, A. B.; Kovalev, Y. Y.; Lister, M. L.; Savolainen, T.

2017-07-01

We present 15 GHz stacked VLBA images of 373 jets associated with active galactic nuclei (AGNs) having at least five observing epochs within a 20 yr time interval 1994-2015 from the Monitoring Of Jets in Active galactic nuclei with VLBA Experiments (MOJAVE) programme and/or its precursor, the 2-cm VLBA Survey. These data are supplemented by 1.4 GHz single-epoch VLBA observations of 135 MOJAVE AGNs to probe larger scale jet structures. The typical jet geometry is found to be close to conical on scales from hundreds to thousands of parsecs, while a number of galaxies show quasi-parabolic streamlines on smaller scales. A true jet geometry in a considerable fraction of AGNs appears only after stacking epochs over several years. The jets with significant radial accelerated motion undergo more active collimation. We have analysed total intensity jet profiles transverse to the local jet ridgeline and derived both apparent and intrinsic opening angles of the flows, with medians of 21.5° and 1.3°, respectively. The Fermi LAT-detected gamma-ray AGNs in our sample have, on average, wider apparent and narrower intrinsic opening angle, and smaller viewing angle than non-LAT-detected AGNs. We have established a highly significant correlation between the apparent opening angle and gamma-ray luminosity, driven by Doppler beaming and projection effects.

Investigating the host galaxies of luminous AGN in the local universe with integral field spectroscopy

NASA Astrophysics Data System (ADS)

McElroy, Rebecca; Croom, Scott; Husemann, Bernd; Close AGN Reference Survey; SAMI Galaxy Survey

2017-01-01

This thesis investigates how galaxies and their super massive black holes coevolve. We use integral field spectroscopy to search for evidence of AGN feedback and triggering. We demonstrate that outflows are ubiquitous among luminous local type 2 AGN using observations from the AAT's SPIRAL instrument. Using multiple component Gaussian emission line decomposition we are able to disentangle the kinematic and ionisation properties of these winds. This allows us to argue that the outflows from these AGN are directly impacting the surrounding ISM within the galaxies. We search for evidence of AGN triggering using data from The Close AGN Reference Survey (CARS). CARS aims to provide a detailed multi-wavelength view of 40 nearby (0.01 < z < 0.06) unobscured AGN to study the link between AGN and their host galaxies. The primary CARS observations come from the MUSE integral field unit on the VLT, and complementary multi-wavelength observations have been approved from SOFIA, Chandra, VLA, HST, and others. We compare the stellar kinematics of active galaxies from CARS to similar inactive galaxies. We then use kinemetry to estimate the degree of dynamical disturbance, to determine whether active nuclei are preferentially hosted in dynamically disturbed or merging systems. Finally, we highlight the discovery of an AGN that has changed spectral type not once, but twice. So called ‘changing look’ AGN are an uncommon phenomenon, but twice changed AGN are much rarer. This AGN first transitioned from a narrow line AGN (type 2) to a broad line AGN (type 1) in the 1980s. It was recently observed as part of CARS. Examination of the MUSE data for this particular source showed that it no longer had the spectral features typical of a type 1 AGN. The continuum emission from the accretion disk was no longer visible and the broad lines were dramatically diminished. In this talk we describe the possible reasons for this change, supported by analysis of multi-epoch optical photometry and

Compton-thick AGN at high and low redshift

NASA Astrophysics Data System (ADS)

Akylas, A.; Georgantopoulos, I.; Corral, A.; Ranalli, P.; Lanzuisi, G.

2017-10-01

The most obscured sources detected in X-ray surveys, the Compton-thick AGN present great interest both because they represent the hidden side of accretion but also because they may signal the AGN birth. We analyse the NUSTAR observations from the serendipitous observations in order to study the Compton-thick AGN at the deepest possible ultra-hard band (>10 keV). We compare our results with our SWIFT/BAT findings in the local Universe, as well as with our results in the CDFS and COSMOS fields. We discuss the comparison with X-ray background synthesis models finding that a low fraction of Compton-thick sources (about 15 per cent of the obscured population) is compatible with both the 2-10keV band results and those at harder energies.

ISO Key Project: Exploring the Full Range of Quasar/AGN Properties

NASA Technical Reports Server (NTRS)

Wilkes, B.

2001-01-01

The origin of the infrared emission in Active Galactic Nuclei (AGN), whose strength is comparable to the optical/ultra-violet (OUV) emission, is generally thought to be a combination of thermal emission from dust and non-thermal, synchrotron emission. Although data are sparse, particularly in the far-infrared, the broad wavelength range of this emission suggests a wide range of temperatures and a combination of AGN and starburst heating mechanisms. The strength of the non-thermal emission is expected to be related to the radio emission. While this scenario is well-established, basic questions, such as the spatial and temperature distribution of the dust, the relative importance of AGN and starburst heating, and the significance of the non-thermal contribution, remain largely undetermined. The wide wavelength range of the Infrared Space Observatory (ISO) combined with its arcmin spatial resolution and increased sensitivity facilitated the observation of a larger subset of the AGN population than previously covered, allowing these questions to be investigated in more detail. This paper will review the spectral energy distributions (SED) of AGN with particular emphasis on the infrared emission and on ISO contributions to our knowledge. Preliminary results from ISO observations of X-ray selected and high-redshift AGN will be described.

Fermi-LAT observation of nonblazar AGNs

NASA Astrophysics Data System (ADS)

Sahakyan, N.; Baghmanyan, V.; Zargaryan, D.

2018-06-01

Context. Fermi Large Area Telescope (Fermi-LAT) has recently detected γ-ray emission from active galactic nuclei (AGN) that do not show clear evidence for optical blazar characteristics or have jets pointing away from the observer (nonblazar AGNs). These are interesting γ-ray emitters providing an alternative approach to studying high energy emission processes. Aims: This paper investigates the spectral and temporal properties of γ-ray emission from nonblazar AGNs using the recent Fermi-LAT observational data. Methods: The data collected by Fermi-LAT during 2008-2015, from the observations of 26 nonblazar AGNs, including 11 Fanaroff-Riley Type I (FRI) and ten FRII radio galaxies and steep spectrum radio quasars (SSRQs) and five narrow line seyfert 1s (NLSy1s) are analysed using the new PASS 8 event selection and instrument response function. Possible spectral changes above GeV energies are investigated with a detailed spectral analysis. Light curves generated with normal and adaptive time bins are used to study the γ-ray flux variability. Results: Non-blazar AGNs have a γ-ray photon index in the range of 1.84-2.86 and a flux varying from a few times 10-9 photon cm-2 s-1 to 10-7 photon cm-2 s-1. Over long time periods, the power law provides an adequate description of the γ-ray spectra of almost all sources. Significant curvature is observed in the γ-ray spectra of NGC 1275, NGC 6251, SBS 0846 + 513, and PMN J0948 + 0022 and their spectra are better described by log parabola or by the power law with exponential cut-off models. The γ-ray spectra of PKS 0625-25 and 3C 380 show a possible deviation from a simple power-law shape, indicating a spectral cut-off around the observed photon energy of Ecut = 131.2 ± 88.04 GeV and Ecut = 55.57 ± 50.74 GeV, respectively. Our analysis confirms the previous finding of an unusual spectral turnover in the γ-ray spectrum of Cen A: the photon index changes from Γ = 2.75 ± 0.02 to 2.31 ± 0.1 at 2.35 ± 0.08 GeV. In the �

Acute and long-term effects of trophic exposure to silver nanospheres in the central nervous system of a neotropical fish Hoplias intermedius.

PubMed

Klingelfus, T; Lirola, J R; Oya Silva, L F; Disner, G R; Vicentini, M; Nadaline, M J B; Robles, J C Z; Trein, L M; Voigt, C L; Silva de Assis, H C; Mela, M; Leme, D M; Cestari, M M

2017-12-01

Nanotechnologies are at the center of societal interest, due to their broad spectrum of application in different industrial products. The current concern about nanomaterials (NMs) is the potential risks they carry for human health and the environment. Considering that NMs can reach bodies of water, there is a need for studying the toxic effects of NMs on aquatic organisms. Among the NMs' toxic effects on fish, the interactions between NMs and the nervous system are yet to be understood. For this reason, our goal was to assess the neurotoxicity of polyvinylpyrrolidone coated silver nanospheres [AgNS (PVP coated)] and compare their effects in relation to silver ions (Ag + ) in carnivorous Hoplias intermedius fish after acute and subchronic trophic exposure through the analysis of morphological (retina), biochemical (brain) and genetic biomarkers (brain and blood). For morphological biomarkers, damage by AgNS (PVP coated) in retina was found, including morphological changes in rods, cones, hemorrhage and epithelium rupture, and also deposition of AgNS (PVP coated) in retina and sclera. In the brain biomarkers, AgNS (PVP coated) did not disturb acetylcholinesterase activity. However, lowered migration of the DNA tail in the Comet Assay of blood and brain cells was observed for all doses of AgNS (PVP coated), for both acute and subchronic bioassays, and in a dose-dependent manner in acute exposure. Ag + also reduced the level of DNA damage only under subchronic conditions in the brain cells. In general, the results demonstrated that AgNS (PVP coated) do not cause similar effects in relation to Ag + . Moreover, the lowered level of DNA damage detected by Comet Assay suggests that AgNS (PVP coated) directly interacts with DNA of brain and blood cells, inducing DNA-DNA or DNA-protein crosslinks. Therefore, the AgNS (PVP coated) accumulating, particularly in the retina, can lead to a competitive disadvantage for fish, compromising their survival. Copyright © 2017 Elsevier

Extracting information from AGN variability

NASA Astrophysics Data System (ADS)

Kasliwal, Vishal P.; Vogeley, Michael S.; Richards, Gordon T.

2017-09-01

Active galactic nuclei (AGNs) exhibit rapid, high-amplitude stochastic flux variations across the entire electromagnetic spectrum on time-scales ranging from hours to years. The cause of this variability is poorly understood. We present a Green's function-based method for using variability to (1) measure the time-scales on which flux perturbations evolve and (2) characterize the driving flux perturbations. We model the observed light curve of an AGN as a linear differential equation driven by stochastic impulses. We analyse the light curve of the Kepler AGN Zw 229-15 and find that the observed variability behaviour can be modelled as a damped harmonic oscillator perturbed by a coloured noise process. The model power spectrum turns over on time-scale 385 d. On shorter time-scales, the log-power-spectrum slope varies between 2 and 4, explaining the behaviour noted by previous studies. We recover and identify both the 5.6 and 67 d time-scales reported by previous work using the Green's function of the Continuous-time AutoRegressive Moving Average equation rather than by directly fitting the power spectrum of the light curve. These are the time-scales on which flux perturbations grow, and on which flux perturbations decay back to the steady-state flux level, respectively. We make the software package kālī used to study light curves using our method available to the community.

How fast can an AGN shut down? XMM-Newton observation of IC 2497

NASA Astrophysics Data System (ADS)

Schawinski, Kevin

2008-10-01

We propose to observe IC 2497 with XMM-Newton to detect, or rule out, an obscured AGN that might account for the illumination of `Hanny's Voorwerp'. The Voorwerp is a highly ionised cloud of gas extended over 15-25 kpc next to the spiral galaxy IC 2497. There is no source of ionisation within the Voorwerp, implicating a luminous 1E44 erg/s AGN in IC 2497 as the source. Swift XRT observations do not yield a detection, allowing the presence of a highly obscured, sufficiently luminous AGN. With 34 ksec of XMM observations, we could detect an obscured AGN down to 1E42 erg/s. We can thus either locate an obscured AGN, or we can for the first time constrain the shutdown time scale for a powerful AGN, as it drops by a factor of 100 in luminosity in 1E5 years.

No evidence for a significant AGN contribution to cosmic hydrogen reionization

NASA Astrophysics Data System (ADS)

Parsa, Shaghayegh; Dunlop, James S.; McLure, Ross J.

2018-03-01

We reinvestigate a claimed sample of 22 X-ray detected active galactic nuclei (AGN) at redshifts z > 4, which has reignited the debate as to whether young galaxies or AGN reionized the Universe. These sources lie within the Great Observatories Origins Deep Survey-South (GOODS-S)/Cosmic Assembly Near-Infrared Deep Extragalactic Legacy Survey (CANDELS) field, and we examine both the robustness of the claimed X-ray detections (within the Chandra 4Ms imaging) and perform an independent analysis of the photometric redshifts of the optical/infrared counterparts. We confirm the reality of only 15 of the 22 reported X-ray detections, and moreover find that only 12 of the 22 optical/infrared counterpart galaxies actually lie robustly at z > 4. Combining these results we find convincing evidence for only seven X-ray AGN at z > 4 in the GOODS-S field, of which only one lies at z > 5. We recalculate the evolving far-ultraviolet (1500 Å) luminosity density produced by AGN at high redshift, and find that it declines rapidly from z ≃ 4 to z ≃ 6, in agreement with several other recent studies of the evolving AGN luminosity function. The associated rapid decline in inferred hydrogen ionizing emissivity contributed by AGN falls an order-of-magnitude short of the level required to maintain hydrogen ionization at z ≃ 6. We conclude that all available evidence continues to favour a scenario in which young galaxies reionized the Universe, with AGN making, at most, a very minor contribution to cosmic hydrogen reionization.

VizieR Online Data Catalog: Gamma-ray AGN type determination (Hassan+, 2013)

NASA Astrophysics Data System (ADS)

Hassan, T.; Mirabal, N.; Contreras, J. L.; Oya, I.

2013-11-01

In this paper, we employ Support Vector Machines (SVMs) and Random Forest (RF) that embody two of the most robust supervised learning algorithms available today. We are interested in building classifiers that can distinguish between two AGN classes: BL Lacs and FSRQs. In the 2FGL, there is a total set of 1074 identified/associated AGN objects with the following labels: 'bzb' (BL Lacs), 'bzq' (FSRQs), 'agn' (other non-blazar AGN) and 'agu' (active galaxies of uncertain type). From this global set, we group the identified/associated blazars ('bzb' and 'bzq' labels) as the training/testing set of our algorithms. (2 data files).

The cosmic evolution of massive black holes in the Horizon-AGN simulation

NASA Astrophysics Data System (ADS)

Volonteri, M.; Dubois, Y.; Pichon, C.; Devriendt, J.

2016-08-01

We analyse the demographics of black holes (BHs) in the large-volume cosmological hydrodynamical simulation Horizon-AGN. This simulation statistically models how much gas is accreted on to BHs, traces the energy deposited into their environment and, consequently, the back-reaction of the ambient medium on BH growth. The synthetic BHs reproduce a variety of observational constraints such as the redshift evolution of the BH mass density and the mass function. Strong self-regulation via AGN feedback, weak supernova feedback, and unresolved internal processes result in a tight BH-galaxy mass correlation. Starting at z ˜ 2, tidal stripping creates a small population of BHs over-massive with respect to the halo. The fraction of galaxies hosting a central BH or an AGN increases with stellar mass. The AGN fraction agrees better with multi-wavelength studies, than single-wavelength ones, unless obscuration is taken into account. The most massive haloes present BH multiplicity, with additional BHs gained by ongoing or past mergers. In some cases, both a central and an off-centre AGN shine concurrently, producing a dual AGN. This dual AGN population dwindles with decreasing redshift, as found in observations. Specific accretion rate and Eddington ratio distributions are in good agreement with observational estimates. The BH population is dominated in turn by fast, slow, and very slow accretors, with transitions occurring at z = 3 and z = 2, respectively.

AGN Science with STROBE-X

NASA Astrophysics Data System (ADS)

Ballantyne, David; Balokovic, Mislav; Garcia, Javier; Koss, Michael; STROBE-X

2018-01-01

The probe concept STROBE-X, with its combination of large collecting area, wide-field monitor, broad bandpass, and rapid timing capability, is a powerful tool for studying many aspects of AGN astrophysics. This unique combination of features opens up the possibility for studying AGNs in ways current and other future missions are unable to accomplish. Here, we show a few of the novel new investigations made possible by STROBE-X: probing the structure of the BLR and torus with reverberation of the narrow Fe Kα line and line-of-sight column density, tracking changes in coronal parameters, investigating the origin of the soft excess, Fe Kα emission line surveys, and efficient Compton-thick characterization. Additional ideas and suggestions are always welcome and can be communicated to any member of the STROBE-X team.

OSSE Observations of Seyfert AGN

NASA Astrophysics Data System (ADS)

Johnson, W. N.; Grove, J. E.; Kinzer, R. L.; Kroeger, R. A.; Kurfess, J. D.; Strickman, M. S.; McNaron-Brown, K.; Grabelsky, D. A.; Purcell, W. R.; Ulmer, M. P.; Jung, G. V.; Cameron, R. A.

1993-12-01

In the first two years of the Compton Gamma Ray Observatory mission, the Oriented Scintillation Spectrometer Experiment (OSSE) has observed about two dozen Seyfert active galactic nuclei (AGN) selected from the HEAO-1 list (Rothschild et al. 1983) and intense X-ray sources detected by EXOSAT and Ginga. The OSSE observations in the 50 keV - 10 MeV range indicate spectra which, on average, are significantly softer than the power law photon index of Gamma =1.7 which is generally reported in the Xray band. The average spectrum is well described by exponential or thermal Comptonization models indicating a break in the spectrum near 100 keV. We summarize the OSSE observations of AGN and present the average Seyfert spectrum above 50 keV. Rothschild, R.E., et al. 1983, Ap. J., 269, 423.

AGN Outflow Shocks on Bonnor–Ebert Spheres

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dugan, Zachary; Silk, Joseph; Rahman, Mubdi

Feedback from active galactic nuclei (AGNs) and subsequent jet cocoons and outflow bubbles can have a significant impact on star formation in the host galaxy. To investigate feedback physics on small scales, we perform hydrodynamic simulations of realistically fast AGN winds striking Bonnor–Ebert spheres and examine gravitational collapse and ablation. We test AGN wind velocities ranging from 300 to 3000 km s{sup −1} and wind densities ranging from 0.5 to 10 m {sub p} cm{sup −3}. We include heating and cooling of low- and high-temperature gas, self-gravity, and spatially correlated perturbations in the shock, with a maximum resolution of 0.01more » pc. We find that the ram pressure is the most important factor that determines the fate of the cloud. High ram pressure winds increase fragmentation and decrease the star formation rate, but they also cause star formation to occur on a much shorter timescale and with increased velocities of the newly formed stars. We find a threshold ram pressure of ∼2 × 10{sup −8} dyn cm{sup −2} above which stars are not formed because the resulting clumps have internal velocities large enough to prevent collapse. Our results indicate that simultaneous positive and negative feedback will be possible in a single galaxy, as AGN wind parameters will vary with location within a galaxy.« less

Fast Ionized X-Ray Absorbers in AGNs

NASA Technical Reports Server (NTRS)

Fukumura, K.; Tombesi, F.; Kazanas, D.; Shrader, C.; Behar, E.; Contopoulos, I.

2016-01-01

We investigate the physics of the X-ray ionized absorbers often identified as warm absorbers (WAs) and ultra-fast outflows (UFOs) in Seyfert AGNs from spectroscopic studies in the context of magnetically-driven accretion-disk wind scenario. Launched and accelerated by the action of a global magnetic field anchored to an underlying accretion disk around a black hole, outflowing plasma is irradiated and ionized by an AGN radiation field characterized by its spectral energy density (SED). By numerically solving the Grad-Shafranov equation in the magnetohydrodynamic (MHD) framework, the physical property of the magnetized disk-wind is determined by a wind parameter set, which is then incorporated into radiative transfer calculations with xstar photoionization code under heating-cooling equilibrium state to compute the absorber's properties such as column density N(sub H), line-of-sight (LoS) velocity v, ionization parameter xi, among others. Assuming that the wind density scales as n varies as r(exp. -1), we calculate theoretical absorption measure distribution (AMD) for various ions seen in AGNs as well as line spectra especially for the Fe K alpha absorption feature by focusing on a bright quasar PG 1211+143 as a case study and show the model's plausibility. In this note we demonstrate that the proposed MHD-driven disk-wind scenario is not only consistent with the observed X-ray data, but also help better constrain the underlying nature of the AGN environment in a close proximity to a central engine.

Fast ionized X-ray absorbers in AGNs

NASA Astrophysics Data System (ADS)

Fukumura, K.; Tombesi, F.; Kazanas, D.; Shrader, C.; Behar, E.; Contopoulos, I.

2016-05-01

We investigate the physics of the X-ray ionized absorbers often identified as warm absorbers (WAs) and ultra-fast outflows (UFOs) in Seyfert AGNs from spectroscopic studies in the context of magnetically-driven accretion-disk wind scenario. Launched and accelerated by the action of a global magnetic field anchored to an underlying accretion disk around a black hole, outflowing plasma is irradiated and ionized by an AGN radiation field characterized by its spectral energy density (SED). By numerically solving the Grad-Shafranov equation in the magnetohydrodynamic (MHD) framework, the physical property of the magnetized disk-wind is determined by a wind parameter set, which is then incorporated into radiative transfer calculations with xstar photoionization code under heating-cooling equilibrium state to compute the absorber's properties such as column density N_H, line-of-sight (LoS) velocity v, ionization parameter ξ, among others. Assuming that the wind density scales as n ∝ r-1, we calculate theoretical absorption measure distribution (AMD) for various ions seen in AGNs as well as line spectra especially for the Fe Kα absorption feature by focusing on a bright quasar PG 1211+143 as a case study and show the model's plausibility. In this note we demonstrate that the proposed MHD-driven disk-wind scenario is not only consistent with the observed X-ray data, but also help better constrain the underlying nature of the AGN environment in a close proximity to a central engine.

Self-consistent two-phase AGN torus models⋆. SED library for observers

NASA Astrophysics Data System (ADS)

Siebenmorgen, Ralf; Heymann, Frank; Efstathiou, Andreas

2015-11-01

We assume that dust near active galactic nuclei (AGNs) is distributed in a torus-like geometry, which can be described as a clumpy medium or a homogeneous disk, or as a combination of the two (i.e. a two-phase medium). The dust particles considered are fluffy and have higher submillimeter emissivities than grains in the diffuse interstellar medium. The dust-photon interaction is treated in a fully self-consistent three-dimensional radiative transfer code. We provide an AGN library of spectral energy distributions (SEDs). Its purpose is to quickly obtain estimates of the basic parameters of the AGNs, such as the intrinsic luminosity of the central source, the viewing angle, the inner radius, the volume filling factor and optical depth of the clouds, and the optical depth of the disk midplane, and to predict the flux at yet unobserved wavelengths. The procedure is simple and consists of finding an element in the library that matches the observations. We discuss the general properties of the models and in particular the 10 μm silicate band. The AGN library accounts well for the observed scatter of the feature strengths and wavelengths of the peak emission. AGN extinction curves are discussed and we find that there is no direct one-to-one link between the observed extinction and the wavelength dependence of the dust cross sections. We show that objects in the library cover the observed range of mid-infrared colors of known AGNs. The validity of the approach is demonstrated by matching the SEDs of a number of representative objects: Four Seyferts and two quasars for which we present new Herschel photometry, two radio galaxies, and one hyperluminous infrared galaxy. Strikingly, for the five luminous objects we find that pure AGN models fit the SED without needing to postulate starburst activity. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.The SED

XMM-Newton observations of the Lockman Hole IV: spectra of the brightest AGN

NASA Astrophysics Data System (ADS)

Mateos, S.; Barcons, X.; Carrera, F. J.; Ceballos, M. T.; Hasinger, G.; Lehmann, I.; Fabian, A. C.; Streblyanska, A.

2005-12-01

This paper presents the results of a detailed X-ray spectral analysis of a sample of 123 X-ray sources detected with XMM-Newton in the Lockman Hole field. This is the deepest observation carried out with XMM-Newton with more that 600 ks of good EPIC-pn data. We have spectra with good signal to noise (>500 source counts) for all objects down to 0.2-12 keV fluxes of 5×10-15 erg cm-2 s-1 (flux limit of 6×10-16 erg cm-2 s-1 in the 0.5-2 and 2-10 keV bands). At the time of the analysis, we had optical spectroscopic identifications for 60% of the sources, 46 being optical type-1 AGN and 28 optical type-2 AGN. Using a single power law model our sources' average spectral slope hardens at faint 0.5-2 keV fluxes but not at faint 2-10 keV fluxes. We have been able to explain this effect in terms of an increase in X-ray absorption at faint fluxes. We did not find in our data any evidence for the existence of a population of faint intrinsically harder sources. The average spectral slope of our sources is 1.9, with an intrinsic dispersion of 0.28. We detected X-ray absorption (F-test significance ≥95%) in 37% of the sources, 10% in type-1 AGN (rest-frame {NH ˜ 1.6 × 1021{-}1.2 × 1022 cm-2}) and 77% (rest-frame {NH ˜ 1.5 ×1021{-}4× 1023 cm-2}) in type-2 AGN. Using X-ray fluxes corrected for absorption, the fraction of absorbed objects and the absorbing column density distribution did not vary with X-ray flux. Our type-1 and type-2 AGN do not appear to have different continuum shapes, but the distribution of intrinsic (rest-frame) absorbing column densities is different among both classes. A significant fraction of our type-2 AGN (5 out of 28) were found to display no substantial absorption ({NH<1021 cm-2}). We discuss possible interpretations to this in terms of Compton-thick AGN and intrinsic Broad Line Region properties. An emission line compatible with Fe Kα was detected in 8 sources (1 type-1 AGN, 5 type-2 AGN and 2 unidentified) with rest frame equivalent widths

X-Ray Absorption, Nuclear Infrared Emission, and Dust Covering Factors of AGNs: Testing Unification Schemes

NASA Astrophysics Data System (ADS)

Mateos, S.; Carrera, F. J.; Alonso-Herrero, A.; Hernán-Caballero, A.; Barcons, X.; Asensio Ramos, A.; Watson, M. G.; Blain, A.; Caccianiga, A.; Ballo, L.; Braito, V.; Ramos Almeida, C.

2016-03-01

We present the distributions of the geometrical covering factors of the dusty tori (f2) of active galactic nuclei (AGNs) using an X-ray selected complete sample of 227 AGNs drawn from the Bright Ultra-hard XMM-Newton Survey. The AGNs have z from 0.05 to 1.7, 2-10 keV luminosities between 1042 and 1046 erg s-1, and Compton-thin X-ray absorption. Employing data from UKIDSS, 2MASS, and the Wide-field Infrared Survey Explorer in a previous work, we determined the rest-frame 1-20 μm continuum emission from the torus, which we model here with the clumpy torus models of Nenkova et al. Optically classified type 1 and type 2 AGNs are intrinsically different, with type 2 AGNs having, on average, tori with higher f2 than type 1 AGNs. Nevertheless, ˜20% of type 1 AGNs have tori with large covering factors, while ˜23%-28% of type 2 AGNs have tori with small covering factors. Low f2 are preferred at high AGN luminosities, as postulated by simple receding torus models, although for type 2 AGNs the effect is certainly small. f2 increases with the X-ray column density, which implies that dust extinction and X-ray absorption take place in material that share an overall geometry and most likely belong to the same structure, the putative torus. Based on our results, the viewing angle, AGN luminosity, and also f2 determine the optical appearance of an AGN and control the shape of the rest-frame ˜1-20 μm nuclear continuum emission. Thus, the torus geometrical covering factor is a key ingredient of unification schemes.

Coeval Starburst and AGN Activity in the CDFS

NASA Astrophysics Data System (ADS)

Brusa, M.; Fiore, F.

2009-10-01

Here we present a study on the host galaxies properties of obscured Active Galactic Nuclei (AGN) detected in the CDFS 1Ms observation and for which deep K-band observations obtained with ISAAC@VLT are available. The aim of this study is to characterize the host galaxies properties of obscured AGN in terms of their stellar masses, star formation rates, and specific star formation rates. To this purpose we refined the X-ray/optical association of 179 1 Ms sources in the MUSIC area, using a three-bands (optical, K, and IRAC) catalog for the counterparts search and we derived the rest frame properties from SED fitting. We found that the host of obscured AGN at z>1 are associated with luminous, massive, red galaxies with significant star formation rates episodes still ongoing in about 50% of the sample.

Detection of viral antigens in renal tissue of glomerulonephritis patients without serological evidence of hepatitis B virus and hepatitis C virus infection.

PubMed

Kong, Dan; Wu, Di; Wang, Tianzhen; Li, Tianzhu; Xu, Shengjie; Chen, Fulai; Jin, Xiaoming; Lou, Ge

2013-07-01

Glomerulonephritis is an important extrahepatic manifestation of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection. HBV and HCV infection may be occult, and they are often overlooked by both patients and doctors. The aim of this study was to assess the importance of HBV and HCV infection in glomerulonephritis patients with undetectable HBV surface antigen (HBsAg) and HCV antibody in serum. The HBsAg, the HBV core antigen (HBcAg), and the HCV antigen were detected using immunohistochemistry in frozen renal tissues of 500 glomerulonephritis patients without serological evidence of HBV and HCV infection. Electron microscopy was used to trace the virus particles, and clinicopathological features were also reviewed. HBsAg or HBcAg was positive in nine out of 500 cases (9/500, 1.8%). Three cases were HBsAg-positive and another six cases were HBcAg-positive. The HCV antigen was found in eight cases (8/500, 1.6%). There was one case of HBV and HCV co-infection (1/500, 0.2%). Under electron microscopy, virus particles were found in the base membrane and cytoplasm of endotheliocytes in the glomerulus. The most common clinical manifestation was nephrotic syndrome (9/18), followed by nephritic syndrome (7/18). Membranous nephropathy was the most common pathological diagnosis (5/18), followed by mesangioproliferative glomerulonephritis (4/18) and IgA nephropathy (4/18). Occult HBV and HCV infection might be implicated in HBV- or HCV-associated glomerulonephritis. More attention should be focused on the underlying cause. Copyright © 2013 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Twenty-two emission-line AGNs from the HEAO-1 X-ray survey

NASA Technical Reports Server (NTRS)

Remillard, R. A.; Bradt, H. V. D.; Brissenden, R. J. V.; Buckley, D. A. H.; Roberts, W.; Schwartz, D. A.; Stroozas, B. A.; Tuohy, I. R.

1993-01-01

We report 22 emission-line AGN as bright, hard X-ray sources. All of them appear to be new classifications with the exception of one peculiar IRAS source which is a known quasar and has no published spectrum. This sample exhibits a rich diversity in optical spectral properties and luminosities, ranging from a powerful broad-absorption-line quasar to a weak nucleus embedded in a nearby NGC galaxy. Two cases confer X-ray luminosities in excess of 10 exp 47 erg/s. However, there is a degree of uncertainty in the X-ray identification for the AGN fainter than V about 16.5. Optically, several AGN exhibit very strong Fe II emission. One Seyfert galaxy with substantial radio flux is an exception to the common association of strong Fe II emission and radio-quiet AGN. The previously recognized IRAS quasar shows extreme velocities in the profiles of the forbidden lines; the 0 III pair is broadened to the point that the lines are blended. Several of these AGN show evidence of intrinsic obscuration, illustrating the effectiveness of hard X-ray surveys in locating AGN through high column density.

DIAGNOSIS OF RHEUMATIC FEVER AND LIKE CONDITIONS—Evaluation of Certain of the Acute Phase Reactants in a Single Specimen of Blood

PubMed Central

Adams, Forrest H.

1956-01-01

Certain of the acute phase reactant tests were performed on the same specimen of blood from persons with the following states: Normal, acute respiratory disease, streptococcosis, acute rheumatic fever, acute glomerulonephritis, acute rheumatoid arthritis, inactive rheumatic fever, lupus erythematosus, malignant disease, obesity, asthma, and allergic rhinitis. Of the tests performed, the mucoprotein-tyrosine and the antistreptolysin-0 titer when done together appeared to be the most discriminating. It is suggested that the performance of such tests on the same sample of blood might aid in differentiating mild acute rheumatic fever and acute rheumatoid arthritis from each other and also from other disease states. PMID:13343008

The AGN Impact on the Circumgalactic Medium of Cen A

NASA Astrophysics Data System (ADS)

Lehner, Nicolas

2017-08-01

There seems to be broad agreement that feedback from AGN plays a critical role in transforming massive star forming galaxies to quiescent ones and keeping them quenched thereafter. Through the emission of copious amounts of radiation emitted in the active QSO/AGN phase and the deposition of thermal and mechanical energy on scales of hundreds of kpc during the radio phase, AGN feedback shifts the temperatures and ionization states of the gas in the circumgalactic medium (CGM) of these galaxies to higher energies, suppressing cooling that might otherwise provide fuel for new star formation. We propose to observe absorption lines from the CGM of the nearby, very well-studied giant radio-lobe galaxy Cen A to search directly for the signal of AGN feedback impacting the CGM of a galaxy. We will target 4 background QSOs projected 270-340 kpc from the galaxy at a range of azimuthal angles relative to the 300 kpc-long jets and 1 control sight line well away from the jets. These spectra will provide probes of the ionization balance and kinematic structure of the cool/warm CGM. This will be the first attempt to dissect the cool/warm gas in a CGM undergoing interactions with an active AGN.

Tori, Discs, and Winds: The First Ten Years of AGN Interferometry

NASA Astrophysics Data System (ADS)

Hönig, Sebastian F.

Infrared (IR) interferometry has made significant progress over the last 10 years to a level that active galactic nuclei (AGN) are now routine targets for long-baseline interferometers. Almost 50 different objects have been studied today in the near-IR and mid-IR. This allowed for detailed characterisation of the dusty environment of the actively growing black holes. It was possible to show directly that the dust must be arranged in clumps, as had been indirectly inferred from theory and unresolved observations. The dust composition seems to undergo significant evolution from galactic scales to the AGN environment, with the hottest dust close to the sublimation front being dominated by large graphite grains. While the overall distribution of the dusty mass is quite diverse from object to object, indications have been found that the dust distribution may depend on AGN luminosity, with more powerful AGN potentially showing more compact dust structures. Arguably the most exciting discovery was the fact that the bulk of the mid-IR emission in Seyfert galaxies emerges from the polar region of the AGN, which is difficult to reconcile with classical torus models. An alternative model is currently being debated that consists of a dusty disc plus a dusty wind driven by radiation pressure from the central source. This finding has major implications for our understanding of AGN unification and will become a focus of the upcoming generation of instruments at the VLTI. More recently, an application of interferometry to cosmology was proposed to measure precise geometric distances to AGN in the Hubble flow. Further exploration of this method may open up interferometry to a new scientific community.

Hard X-ray spectral properties of distant AGN in the NuSTAR surveys

NASA Astrophysics Data System (ADS)

Del Moro, Agnese

2016-08-01

I will present a study on the average broad X-ray band (~0.5-30 keV) spectral properties of the NuSTAR sources detected in the ECDF-S, EGS and COSMOS fields. Constructing the rest-frame composite spectra of AGN in different hydrogen column density (NH) and 10-40 keV luminosity bins, using Chandra and NuSTAR data, we investigate the typical spectral parameters of the AGN population, such as the photon index, NH, strength of the iron emission line (~6.4 keV) and of the Compton reflection at ~20-30 keV. Placing constraints on the reflection fraction (R) is of particular importance for the synthesis models of the cosmic X-ray background (CXB), as this parameter is strongly linked with the fraction of Compton-thick AGN needed to fit the CXB spectrum. Thanks to its sensitivity at ~20-30 keV, NuSTAR allows for the first time, to directly place such constraints for non-local AGN. We find typical reflection fractions of R~1-1.5, consistent the AGN in the local Universe, with a tentative evidence for the most obscured AGN to have, on average, stronger Compton reflection compared to unobscured AGN. Moreover, contrary to previous works, we do not find significant evidence for a decrease of the reflection strength with luminosity for typical Γ=1.8-1.9. Our results support CXB models that require a relatively small fraction of CT AGN, of the order of ~10-15%.

X-RAY ABSORPTION, NUCLEAR INFRARED EMISSION, AND DUST COVERING FACTORS OF AGNs: TESTING UNIFICATION SCHEMES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mateos, S.; Carrera, F. J.; Alonso-Herrero, A.

2016-03-10

We present the distributions of the geometrical covering factors of the dusty tori (f{sub 2}) of active galactic nuclei (AGNs) using an X-ray selected complete sample of 227 AGNs drawn from the Bright Ultra-hard XMM-Newton Survey. The AGNs have z from 0.05 to 1.7, 2–10 keV luminosities between 10{sup 42} and 10{sup 46} erg s{sup −1}, and Compton-thin X-ray absorption. Employing data from UKIDSS, 2MASS, and the Wide-field Infrared Survey Explorer in a previous work, we determined the rest-frame 1–20 μm continuum emission from the torus, which we model here with the clumpy torus models of Nenkova et al. Opticallymore » classified type 1 and type 2 AGNs are intrinsically different, with type 2 AGNs having, on average, tori with higher f{sub 2} than type 1 AGNs. Nevertheless, ∼20% of type 1 AGNs have tori with large covering factors, while ∼23%–28% of type 2 AGNs have tori with small covering factors. Low f{sub 2} are preferred at high AGN luminosities, as postulated by simple receding torus models, although for type 2 AGNs the effect is certainly small. f{sub 2} increases with the X-ray column density, which implies that dust extinction and X-ray absorption take place in material that share an overall geometry and most likely belong to the same structure, the putative torus. Based on our results, the viewing angle, AGN luminosity, and also f{sub 2} determine the optical appearance of an AGN and control the shape of the rest-frame ∼1–20 μm nuclear continuum emission. Thus, the torus geometrical covering factor is a key ingredient of unification schemes.« less

Optical Time-Domain and Radio Imaging Analyses of the Dynamic Hearts of AGN

NASA Astrophysics Data System (ADS)

Smith, Krista Lynne

Active galactic nuclei (AGN) are among the most extreme objects in the universe: galaxies with a central supermassive black hole feeding on gas from a hot accretion disk. Despite their potential as powerful tools to study topics ranging from relativity to cosmology, they remain quite mysterious. In the first portion of this thesis, we explore how an AGN may influence the formation of stars in its host galaxy. Using high-resolution 22 GHz radio imaging of an X-ray selected sample of radio-quiet AGN, we find that the far-infrared radio correlation for normal star forming galaxies remains valid within a few hundred parsecs of the central engine. Because the core flux is often spatially isolated from star formation, we can also determine that the radio emission in radio-quiet AGN is consistent with both coronal and disk-jet coupling models. Finally, we find that AGN with jet-like radio morphologies have suppressed star formation, possibly indicating ongoing feedback. The second portion of this thesis uses optical AGN light curves to study the physics of accretion. The Kepler spacecraft produces groundbreaking light curves, but its fixed field of view only contained a handful of known AGN. We conduct an X-ray survey of this field, yielding 93 unique X-ray sources identified by optical follow-up spectroscopy as a mixture of AGN and stars. For the AGN, we spectroscopically measure black hole masses and accretion rates. We then analyze a sample of 22 Kepler AGN light curves. We develop a customized pipeline for AGN science with Kepler, a necessary step since the initial data was optimized for the unique goal of exoplanet detection. The light curves display an astonishing variety of behaviors in a new regime of optical variability inaccessible with previous facilities. We find power spectral slopes inconsistent with the damped random walk model, characteristic variability timescales, correlations of variability properties with physical parameters, and bimodal flux

Streptococcus pyogenes strains containing emm12 and emm55 possess a novel gene coding for distantly related SIC protein.

PubMed

Hartas, J; Sriprakash, K S

1999-01-01

Streptococcus pyogenes infection and acute glomerulonephritis (AGN), a non-suppurtave disease, are endemic in the Aboriginal people of the Northern Territory (NT) of Australia. Vir typing, a locus-specific polymerase chain reaction (PCR)-based typing method [Gardiner, Hartas, Currie et al PCR Meth Appl 1995 4: 288-93], has revealed high divergence among the NT streptococcal strains. A total of 76 Vir types (VTs) representing about 95% of the NT isolates were screened for sic, a gene for streptococcal inhibitor of complement function, by PCR and hybridization. This revealed that seven VTs are positive for sic, and there are two classes of the gene: those closely related to sic (CRS) originally described by Akesson, Sjoholm & Bjorck [ J. Biol. Chem. 1996 271: 1081-8] and those distantly related to sic (DRS). Among the CRS-positive VTs, VT16, VT78 and VT91 have emm (gene for M protein) encoding type 1 M protein or related specificity, and VT8 and VT101 contain emm57 or related alleles. Chromosomal location of CRS in emm57 is different from that in emm1 or related strains. The DRS-positive VT18 and VT52 contained emm55 and emm12 respectively, which are phylogenetically related. Strains of S. pyogenes types 1, 12, 55 and 57 are known to be associated with AGN. Restricted distribution of CRS and DRS among the M types historically associated with AGN suggests that these sic alleles may have a role in AGN pathogenesis. Copyright 1999 Academic Press.

Towards A Complete Census of the Compton-thick AGN Population in our Cosmic Backyard

NASA Astrophysics Data System (ADS)

Annuar, Ady

2016-09-01

We propose for Chandra and NuSTAR observations of two local AGNs to characterise their obscuring properties. We are using Chandra and NuSTAR to form the first complete measurement of the column density (N_H) distribution of AGN at D<15 Mpc. Even at this distance the distribution was only 50% complete. We have recently improved this, and found a Compton-thick (CT) AGN fraction of >35%. We also found that Chandra resolution is key in resolving the AGN from off-nuclear X-ray sources. When combined with NuSTAR, this allow us to accurately characterise the broadband spectrum of the AGN, and identify it as CT. These new observations will provide Chandra data for all D<15Mpc AGNs and boost up the N_H distribution up to 85% complete. This will be fully completed with future NuSTAR observations.

THE XMM-NEWTON WIDE FIELD SURVEY IN THE COSMOS FIELD: REDSHIFT EVOLUTION OF AGN BIAS AND SUBDOMINANT ROLE OF MERGERS IN TRIGGERING MODERATE-LUMINOSITY AGNs AT REDSHIFTS UP TO 2.2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Allevato, V.; Hasinger, G.; Salvato, M.

2011-08-01

We present a study of the redshift evolution of the projected correlation function of 593 X-ray selected active galactic nuclei (AGNs) with I{sub AB} < 23 and spectroscopic redshifts z < 4, extracted from the 0.5-2 keV X-ray mosaic of the 2.13 deg{sup 2} XMM- Cosmic Evolution Survey (COSMOS). We introduce a method to estimate the average bias of the AGN sample and the mass of AGN hosting halos, solving the sample variance using the halo model and taking into account the growth of the structure over time. We find evidence of a redshift evolution of the bias factor formore » the total population of XMM-COSMOS AGNs from b-bar (z-bar =0.92)=2.30{+-}0.11 to b-bar (z-bar =1.94)=4.37{+-}0.27 with an average mass of the hosting dark matter (DM) halos log M{sub 0}(h{sup -1} M{sub sun}) {approx} 13.12 {+-} 0.12 that remains constant at all z < 2. Splitting our sample into broad optical line AGNs (BL), AGNs without broad optical lines (NL), and X-ray unobscured and obscured AGNs, we observe an increase of the bias with redshift in the range z-bar = 0.7-2.25 and z-bar = 0.6-1.5 which corresponds to a constant halo mass of log M{sub 0}(h{sup -1} M{sub sun}) {approx} 13.28 {+-} 0.07 and log M{sub 0}(h{sup -1} M{sub sun}) {approx} 13.00 {+-} 0.06 for BL/X-ray unobscured AGNs and NL/X-ray obscured AGNs, respectively. The theoretical models, which assume a quasar phase triggered by major mergers, cannot reproduce the high bias factors and DM halo masses found for X-ray selected BL AGNs with L{sub BOL} {approx} 2 x 10{sup 45} erg s{sup -1}. Our work extends up to z {approx} 2.2 the z {approx}< 1 statement that, for moderate-luminosity X-ray selected BL AGNs, the contribution from major mergers is outnumbered by other processes, possibly secular ones such as tidal disruptions or disk instabilities.« less

Evidence for Merger-driven Growth in Luminous, High- z, Obscured AGNs in the CANDELS/COSMOS Field

DOE PAGES

Donley, J. L.; Kartaltepe, J.; Kocevski, D.; ...

2018-01-23

While major mergers have long been proposed as a driver of both active galactic nucleus (AGN) activity and themore » $${M}_{\\mathrm{BH}}\\mbox{--}{\\sigma }_{\\mathrm{bulge}}$$ relation, studies of moderate to high-redshift Seyfert-luminosity AGN hosts have found little evidence for enhanced rates of interactions. However, both theory and observation suggest that while these AGNs may be fueled by stochastic accretion and secular processes, high-luminosity, high-redshift, and heavily obscured AGNs are the AGNs most likely to be merger-driven. To better sample this population of AGNs, we turn to infrared selection in the CANDELS/COSMOS field. Compared to their lower-luminosity and less obscured X-ray-only counterparts, IR-only AGNs (luminous, heavily obscured AGNs) are more likely to be classified as either irregular ($${50}_{-12}^{+12} \\% $$ versus $${9}_{-2}^{+5} \\% $$) or asymmetric ($${69}_{-13}^{+9} \\% $$ versus $${17}_{-4}^{+6} \\% $$) and are less likely to have a spheroidal component ($${31}_{-9}^{+13} \\% $$ versus $${77}_{-6}^{+4} \\% $$). Furthermore, IR-only AGNs are also significantly more likely than X-ray-only AGNs ($${75}_{-13}^{+8} \\% $$ versus $${31}_{-6}^{+6} \\% $$) to be classified either as interacting or merging in a way that significantly disturbs the host galaxy or as disturbed, though not clearly interacting or merging, which potentially represents the late stages of a major merger. Finally, this suggests that while major mergers may not contribute significantly to the fueling of Seyfert-luminosity AGNs, interactions appear to play a more dominant role in the triggering and fueling of high-luminosity heavily obscured AGNs.« less

[Primary chronic polyarthritis with kidney involvement (mesangiocapillary glomerulonephritis)].

PubMed

Bürkle, P A

1979-01-01

A 34 year old white male patient suffering from seropositive "probable" rheumatoid arthritis developed a severe hypocomplementemic mesangiocapillary glomerulo-nephritis. Rheumatoid factors (Latex test, Waaler-Rose titer) and IgM were markedly elevated in the serum. The third component of complement (C3) was markedly depressed, while the fourth component (C4) was within normal range. The rapid progression of the disease forced us to start an immunosuppressive drug therapy using azathioprine and steroids. Despite marked clinical improvement, e.g. normalisation of complement components, renal function, the disappearance of rheumatoid factor and proteinuria, the second biopsy taken two years later showed unchanged histological and immuno-histological changes of the glomerula.

AGN Heating in Simulated Cool-core Clusters

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Yuan; Ruszkowski, Mateusz; Bryan, Greg L., E-mail: yuanlium@umich.edu

We analyze heating and cooling processes in an idealized simulation of a cool-core cluster, where momentum-driven AGN feedback balances radiative cooling in a time-averaged sense. We find that, on average, energy dissipation via shock waves is almost an order of magnitude higher than via turbulence. Most of the shock waves in the simulation are very weak shocks with Mach numbers smaller than 1.5, but the stronger shocks, although rare, dissipate energy more effectively. We find that shock dissipation is a steep function of radius, with most of the energy dissipated within 30 kpc, more spatially concentrated than radiative cooling loss.more » However, adiabatic processes and mixing (of post-shock materials and the surrounding gas) are able to redistribute the heat throughout the core. A considerable fraction of the AGN energy also escapes the core region. The cluster goes through cycles of AGN outbursts accompanied by periods of enhanced precipitation and star formation, over gigayear timescales. The cluster core is under-heated at the end of each cycle, but over-heated at the peak of the AGN outburst. During the heating-dominant phase, turbulent dissipation alone is often able to balance radiative cooling at every radius but, when this is occurs, shock waves inevitably dissipate even more energy. Our simulation explains why some clusters, such as Abell 2029, are cooling dominated, while in some other clusters, such as Perseus, various heating mechanisms including shock heating, turbulent dissipation and bubble mixing can all individually balance cooling, and together, over-heat the core.« less

Prospects for AGN Science using the ART-XC on the SRG Mission

NASA Technical Reports Server (NTRS)

Swartz, Douglas A.; Elsner, Ronald F.; Gubarev, Mikhail V.; O'Dell, Stephen L.; Ramsey, Brian D.; Bonamente, Massimiliano

2012-01-01

The enhanced hard X-ray sensitivity provided by the Astronomical Roentgen Telescope to the Spectrum Roentgen Gamma mission facilitates the detection of heavily obscured and other hard-spectrum cosmic X-ray sources. The SRG all-sky survey will obtain large, statistically-well-defined samples of active galactic nuclei (AGN) including a significant population of local heavily-obscured AGN. In anticipation of the SRG all-sky survey, we investigate the prospects for refining the bright end of the AGN luminosity function and determination of the local black hole mass function and comparing the spatial distribution of AGN with large-scale structure defined by galaxy clusters and groups. Particular emphasis is placed on studies of the deep survey Ecliptic Pole regions.

Intermediate mass black holes in AGN discs - I. Production and growth

NASA Astrophysics Data System (ADS)

McKernan, B.; Ford, K. E. S.; Lyra, W.; Perets, H. B.

2012-09-01

Here we propose a mechanism for efficiently growing intermediate mass black holes (IMBH) in discs around supermassive black holes. Stellar mass objects can efficiently agglomerate when facilitated by the gas disc. Stars, compact objects and binaries can migrate, accrete and merge within discs around supermassive black holes. While dynamical heating by cusp stars excites the velocity dispersion of nuclear cluster objects (NCOs) in the disc, gas in the disc damps NCO orbits. If gas damping dominates, NCOs remain in the disc with circularized orbits and large collision cross-sections. IMBH seeds can grow extremely rapidly by collisions with disc NCOs at low relative velocities, allowing for super-Eddington growth rates. Once an IMBH seed has cleared out its feeding zone of disc NCOs, growth of IMBH seeds can become dominated by gas accretion from the active galactic nucleus (AGN) disc. However, the IMBH can migrate in the disc and expand its feeding zone, permitting a super-Eddington accretion rate to continue. Growth of IMBH seeds via NCO collisions is enhanced by a pile-up of migrators. We highlight the remarkable parallel between the growth of IMBH in AGN discs with models of giant planet growth in protoplanetary discs. If an IMBH becomes massive enough it can open a gap in the AGN disc. IMBH migration in AGN discs may stall, allowing them to survive the end of the AGN phase and remain in galactic nuclei. Our proposed mechanisms should be more efficient at growing IMBH in AGN discs than the standard model of IMBH growth in stellar clusters. Dynamical heating of disc NCOs by cusp stars is transferred to the gas in an AGN disc helping to maintain the outer disc against gravitational instability. Model predictions, observational constraints and implications are discussed in a companion paper (Paper II).

Spatially offset AGN candidates in the CLASS survey

NASA Astrophysics Data System (ADS)

Skipper, Chris J.; Browne, Ian W. A.

2018-04-01

Prompted by a recent claim by Barrows et al. that X-ray active galactic nuclei (AGNs) are often found significantly offset from the centres of their host galaxies, we have looked for examples of compact radio sources that are offset from the optical centroids of nearby (z < 0.2) galaxies. We have selected a sample of 345 galaxies from the Sloan Digital Sky Survey (SDSS) galaxy catalogue, which have nearby compact radio sources listed in the Cosmic-Lens All Sky Survey (CLASS) catalogue. We find only three matches (˜0.87 per cent of the sample) with offsets greater than 600 milliarcsec (mas), which is considerably fewer than we would have expected from the Barrows et al. X-ray survey. We fit our histogram of offsets with a Rayleigh distribution with σ = 60.5 mas, but find that there is an excess of objects with separations greater than ˜150 mas. Assuming that this excess represents AGNs with real offsets, we place an upper limit of ˜17 per cent on the fraction of offset AGNs in our radio-selected sample. We select 38 objects with offsets greater than 150 mas, and find they have some diverse properties: Some are well known, such as Mrk 273 and Arp 220, some have dust lanes, which may have affected the optical astrometry, and a few are strong new candidates for offset AGNs.

Postinfectious glomerulonephritis secondary to Erythrovirus B19 (Parvovirus B19): case report and review of the literature.

PubMed

Marco, Helena; Guermah, Imane; Matas, Lurdes; Hernández, Alba; Navarro, Maruja; Lopez, Dolores; Bonet, Josep

2016-04-01

A previously healthy 32-yearold woman developed arterial hypertension, proteinuria, and hematuria (nephritic syndrome) with normal renal function and was diagnosed with post-infectious glomerulonephritis secondary to parvovirus B19 infection. The renal biopsy showed endocapillary glomerulonephritis, with positive IgG, C3, and C1q immunoreactivity in the capillary walls and ultrastructural evidence of subendothelial deposits. The diagnosis of parvovirus B19 infection was confirmed by IgG/IgM serological positivity and parvovirus DNA demonstration in both peripheral blood and kidney tissue. Glomerular involvement improved spontaneously. To be noted are the atypical signs and symptoms of our patient who, unlike previously reported cases, failed to show fever, skin rash, or affected relatives.

Why do we see Broad Lines in X-ray Absorbed, Red AGN?

NASA Astrophysics Data System (ADS)

Wilkes, B. J.; Ghosh, Himel; Cutri, R.; Hines, D.; Nelson, B.; Schmidt, G. D.; Smith, P. S.

2003-05-01

The Two Micron All-Sky Survey (2MASS) red AGN catalog has revealed a previously unknown population whose number density rivals that of optically-selected AGN as found in the many, relatively shallow surveys (e.g. PG, Hamburg). The Chandra X-ray spectra of these red, mostly broad-line AGN are hard. This, combined with their unusually high optical polarization, suggests substantial obscuration (log NH = 21-23 cm-2) toward the nuclear energy source, despite a clear view of the broad emission line region. We have expanded our Chandra-observed sub-sample to include 20 more 2MASS AGN yielding a set of 46 which includes all available optical classes. This sample is thus pre-selected for complex absorption and sufficient to study the relative X-ray and optical obscuration for each AGN class. Those observed to date continue the lack of a relation between the X-ray hardness ratio and optical class noted in our earlier sample. Combining this with X-ray spectral fits where we have sufficient counts and with our multi-wavelength data, we compare the spectral energy distributions with those of normal and other red AGN and investigate possible scenarios for the absorbing material. We gratefully ackowledge the financial support of NASA grant: GO1-2112A

X-Ray Absorbed, Broad-Lined, Red AGN and the Cosmic X-Ray Background

NASA Technical Reports Server (NTRS)

Mushotzky, Richard (Technical Monitor); Wilkes, Belinda

2005-01-01

We have obtained XMM spectra for five red, 2MASS AGN, selected from a sample observed by Chandra to be X-ray bright and to cover a range of hardness ratios. Our results confirm the presence of substantial absorbing material in three sources which have optical classifications ranging from Type 1 to Type 2, with an intrinsically flat (hard) power law continuum indicated in the other two. The presence of both X-ray absorption and broad optical emission lines with the usual strength suggests either a small (nuclear) absorber or a favored viewing angle so as to cover the X-ray source but not the broad emission line region (BELR). A soft excess is detected in all three Type 1 sources. We speculate that this soft X-ray emission may arise in an extended region of ionized gas, perhaps linked with the polarized (scattered) light which is a feature of these sources. The spectral complexity revealed by XMM emphasizes the limitations of the low S/N Chandra data. Overall, the new XMM results strengthen our conclusions (Wilkes et al. 2002) that the observed X-ray continua of red AGN are unusually hard at energies greater than 2 keV. Whether due to substantial line-of-sight absorption or to an intrinsically hard or reflection-dominated spectrum, these 'red' AGN have an observed spectral form consistent with contributing significantly to the missing had absorbed population of the Cosmic X-ray Background (CXRB). When absorption and or reflection is taken into account, all these AGN have power law slopes typical of broad-line (Type 1) AGN (Gamma approximately 1.9). This appears to resolve the spectral paradox which for so long has existed between the CXRB and the AGN thought to be the dominant contributors. It also suggests two scenarios whereby Type 1 AGN/QSOs may be responsible for a significant fraction of the CXRB at energies above 2 keV: 1) X-ray absorbed AGN/QSOs with visible broad emission lines; 2) AGN/QSOs with complex spectra whose hardness greater than 2 keV is not

A Hubble Space Telescope Survey of Intrinsic Absorption in Nearby AGN

NASA Astrophysics Data System (ADS)

Dashtamirova, Dzhuliya; Dunn, Jay P.; Crenshaw, D. Michael

2017-01-01

We present a survey of the intrinsic UV absorption lines in active galactic nuclei (AGN). We limit our study to the ultraviolet spectra of type 1 AGN with a redshift of z < 0.15 as a continuation of the Dunn et al. (2007, 2008) and Crenshaw et al. (1999) studies of smaller samples. We identify approximately 90 AGN fit our redshift specifications in the Mikulski Archive for Space Telescopes (MAST) database with Cosmic Origin Spectrograph (COS) observations. We download and co-add all of the COS spectra. We find that about 80 of these are type 1 AGN. We normalize the COS spectra and identify all of the intrinsic Lyman-alpha, N V, Si IV, and C IV intrinsic absorption features. From these data, we determine the fraction of type 1 AGN with intrinsic absorption in this redshift range and find the global covering factors of the absorbers. We also identify low ionization species as well as excited state lines. A number of objects have multiple epoch COS and/or Space Telescope Imaging Spectrograph (STIS) observations, which we use to investigate the absorption variability.

The Host Galaxies Of UV-selected AGNs At z 2-3

NASA Astrophysics Data System (ADS)

Hainline, Kevin; Shapley, A.; Greene, J.; Steidel, C.

2012-01-01

An important goal for studies of galaxy formation consists of tracing a direct evolutionary connection between the growth of supermassive black holes powering active galactic nuclei (AGNs) and the build-up of stellar mass in their host galaxies. In the local universe, AGNs are preferentially found in bulge-dominated galaxies, but the AGN demographics at earlier epochs are not as well understood. We present a rest-frame UV composite spectrum for a sample of 33 z 2-3 AGNs drawn from the UV-selected Lyman Break Galaxy (LBG) survey. This spectrum shows many emission and absorption features, such as HI Lyman-alpha, NV 1240, NIV] 1483, 1486, CIV 1548, 1550, HeII 1640, and CIII] 1907, 1909. Redshifted SiIV 1394 absorption provides evidence for outflowing high-ionization gas in these objects at speeds of 103 km/s. Finally, using optical, near-IR, and mid-IR photometry, which cover the rest-frame UV to near-IR portions of the galaxies' spectral energy distributions, we perform stellar population synthesis modeling of the sample. Based on these results, we explore the relationship in the host galaxy between AGN activity, maturity of the stellar population, and regulation of star formation.

Autoimmunity to the alpha 3 chain of type IV collagen in glomerulonephritis is triggered by ‘autoantigen complementarity’

PubMed Central

Reynolds, John; Preston, Gloria A.; Pressler, Barrak M.; Hewins, Peter; Brown, Michael; Roth, Aleeza; Alderman, Elizabeth; Bunch, Donna; Jennette, J. Charles; Cook, H. Terence; Falk, Ronald J.; Pusey, Charles D.

2015-01-01

‘Autoantigen complementarity’ is a theory proposing that the initiator of an autoimmune response is not necessarily the autoantigen or its molecular mimic, but may instead be a peptide that is ‘antisense/complementary’ to the autoantigen. We investigated whether such complementary proteins play a role in the immunopathogenesis of autoimmune glomerulonephritis. Experimental autoimmune glomerulonephritis, a model of anti-glomerular basement membrane (GBM) disease, can be induced in Wistar Kyoto (WKY) rats by immunization with the α3 chain of type IV collagen. In this study, WKY rats were immunized with a complementary α3 peptide (c-α3-Gly) comprised of amino acids that ‘complement’ the well characterized epitope on α3(IV)NC1, pCol(24–38). Within 8 weeks post-immunization, these animals developed cresentic glomerulonephritis, similar to pCol(24–38)-immunized rats, while animals immunized with scrambled peptide were normal. Anti-idiotypic antibodies to epitopes from c-α3-Gly-immunized animals were shown to be specific for α3 protein, binding in a region containing sense pCol(24–38) sequence. Interestingly, anticomplementary α3 antibodies were identified in sera from patients with anti-GBM disease, suggesting a role for ‘autoantigen complementarity’ in immunopathogenesis of the human disease. This work supports the idea that autoimmune glomerulonephritis can be initiated through an immune response against a peptide that is anti-sense or complementary to the autoantigen. The implications of this discovery may be far reaching, and other autoimmune diseases could be due to responses to these once unsuspected ‘complementary’ antigens. PMID:25841937

The first 62 AGN observed with SDSS-IV MaNGA - II: resolved stellar populations

NASA Astrophysics Data System (ADS)

Mallmann, Nícolas Dullius; Riffel, Rogério; Storchi-Bergmann, Thaisa; Barboza Rembold, Sandro; Riffel, Rogemar A.; Schimoia, Jaderson; da Costa, Luiz Nicolaci; Ávila-Reese, Vladimir; Sanchez, Sebastian F.; Machado, Alice D.; Cirolini, Rafael; Ilha, Gabriele S.; do Nascimento, Janaína C.

2018-05-01

We present spatially resolved stellar population age maps, average radial profiles and gradients for the first 62 Active Galactic Nuclei (AGN) observed with SDSS-IV MaNGA to study the effects of the active nuclei on the star formation history of the host galaxies. These results, derived using the STARLIGHT code, are compared with a control sample of non-active galaxies matching the properties of the AGN hosts. We find that the fraction of young stellar populations (SP) in high-luminosity AGN is higher in the inner (R≤0.5 Re) regions when compared with the control sample; low-luminosity AGN, on the other hand, present very similar fractions of young stars to the control sample hosts for the entire studied range (1 Re). The fraction of intermediate age SP of the AGN hosts increases outwards, with a clear enhancement when compared with the control sample. The inner region of the galaxies (AGN and control galaxies) presents a dominant old SP, whose fraction decreases outwards. We also compare our results (differences between AGN and control galaxies) for the early and late-type hosts and find no significant differences. In summary, our results suggest that the most luminous AGN seems to have been triggered by a recent supply of gas that has also triggered recent star formation (t ≤ 40 Myrs) in the central region.

The Compton-thick AGN fraction from the deepest X-ray spectroscopy in the CDF-S

NASA Astrophysics Data System (ADS)

Corral, A.; Georgantopoulos, I.; Akylas, A.; Ranalli, P.

2017-10-01

Highly obscured AGN, especially Compton-thick (CT) AGN, likely play a key role in the galaxy-AGN co-evolution scenario. They would comprise the early stages of AGN activity, preceding the AGN-feedback/star-formation quenching phase, during which most of both the SMBH and galaxy growth take place. However, the actual CT fraction among the AGN population is still largely unconstrained. The most reliable way of confirming the obscured nature of an AGN by X-ray spectroscopy, but very deep observations are needed to extend local analyses to larger distances. We will present the X-ray spectral analysis of the deepest X-ray data obtained to date, the almost 7Ms observation of the Chandra Deep Field South. The unprecedented depth of this survey allow us to carry out reliable spectral analyses down to a flux limit of 10^{-16} erg cm^{-2} s^{-1} in the hard 2-8 keV band. Besides the new deeper X-ray data, our approach also includes the implementation of Bayesian inference in the determination of the CT fraction. Our results favor X-ray background synthesis models which postulate a moderate fraction (25%) of CT objects among the obscured AGN population.

Podocytes populate cellular crescents in a murine model of inflammatory glomerulonephritis.

PubMed

Moeller, Marcus J; Soofi, Abdulsalaam; Hartmann, Inge; Le Hir, Michel; Wiggins, Roger; Kriz, Wilhelm; Holzman, Lawrence B

2004-01-01

Cellular crescents are a defining histologic finding in many forms of inflammatory glomerulonephritis. Despite numerous studies, the origin of glomerular crescents remains unresolved. A genetic cell lineage-mapping study with a novel transgenic mouse model was performed to investigate whether visceral glomerular epithelial cells, termed podocytes, are precursors of cells that populate cellular crescents. The podocyte-specific 2.5P-Cre mouse line was crossed with the ROSA26 reporter line, resulting in irreversible constitutive expression of beta-galactosidase in doubly transgenic 2.5P-Cre/ROSA26 mice. In these mice, crescentic glomerulonephritis was induced with a previously described rabbit anti-glomerular basement membrane antiserum nephritis approach. Interestingly, beta-galactosidase-positive cells derived from podocytes adhered to the parietal basement membrane and populated glomerular crescents during the early phases of cellular crescent formation, accounting for at least one-fourth of the total cell mass. In cellular crescents, the proliferation marker Ki-67 was expressed in beta-galactosidase-positive and beta-galactosidase-negative cells, indicating that both cell types contributed to the formation of cellular crescents through proliferation in situ. Podocyte-specific antigens, including WT-1, synaptopodin, nephrin, and podocin, were not expressed by any cells in glomerular crescents, suggesting that podocytes underwent profound phenotypic changes in this nephritis model.

EDDINGTON RATIO DISTRIBUTION OF X-RAY-SELECTED BROAD-LINE AGNs AT 1.0 < z < 2.2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Suh, Hyewon; Hasinger, Günther; Steinhardt, Charles

2015-12-20

We investigate the Eddington ratio distribution of X-ray-selected broad-line active galactic nuclei (AGNs) in the redshift range 1.0 < z < 2.2, where the number density of AGNs peaks. Combining the optical and Subaru/Fiber Multi Object Spectrograph near-infrared spectroscopy, we estimate black hole masses for broad-line AGNs in the Chandra Deep Field South (CDF-S), Extended Chandra Deep Field South (E-CDF-S), and the XMM-Newton Lockman Hole (XMM-LH) surveys. AGNs with similar black hole masses show a broad range of AGN bolometric luminosities, which are calculated from X-ray luminosities, indicating that the accretion rate of black holes is widely distributed. We find a substantial fraction ofmore » massive black holes accreting significantly below the Eddington limit at z ≲ 2, in contrast to what is generally found for luminous AGNs at high redshift. Our analysis of observational selection biases indicates that the “AGN cosmic downsizing” phenomenon can be simply explained by the strong evolution of the comoving number density at the bright end of the AGN luminosity function, together with the corresponding selection effects. However, one might need to consider a correlation between the AGN luminosity and the accretion rate of black holes, in which luminous AGNs have higher Eddington ratios than low-luminosity AGNs, in order to understand the relatively small fraction of low-luminosity AGNs with high accretion rates in this epoch. Therefore, the observed downsizing trend could be interpreted as massive black holes with low accretion rates, which are relatively fainter than less-massive black holes with efficient accretion.« less

Beyond Hydrodynamic Modeling of AGN Heating in Galaxy Clusters

NASA Astrophysics Data System (ADS)

Yang, Hsiang-Yi Karen

Clusters of galaxies hold a unique position in hierarchical structure formation - they are both powerful cosmological probes and excellent astrophysical laboratories. Accurate modeling of the cluster properties is crucial for reducing systematic uncertainties in cluster cosmology. However, theoretical modeling of the intracluster medium (ICM) has long suffered from the "cooling-flow problem" - clusters with short central times or cool cores (CCs) are predicted to host massive inflows of gas that are not observed. Feedback from active galactic nuclei (AGN) is by far the most promising heating mechanism to counteract radiative cooling. Recent hydrodynamic simulations have made remarkable progress reproducing properties of the CCs. However, there remain two major questions that cannot be probed using purely hydrodynamic models: (1) what are the roles of cosmic rays (CRs)? (2) how is the existing picture altered when the ICM is modeled as weakly collisional plasma? We propose to move beyond limitations of pure hydrodynamics and progress toward a complete understanding of how AGN jet-inflated bubbles interact with their surroundings and provide heat to the ICM. Our objectives include: (1) understand how CR-dominated bubbles heat the ICM; (2) understand bubble evolution and sound-wave dissipation in the ICM with different assumptions of plasma properties, e.g., collisionality of the ICM, with or without anisotropic transport processes; (3) Develop a subgrid model of AGN heating that can be adopted in cosmological simulations based on state-of-the-art isolated simulations. We will use a combination of analytical calculations and idealized simulations to advance our understanding of each individual physical process. We will then perform the first three-dimensional (3D) magnetohydrodynamic (MHD) simulations of self-regulated AGN feedback with relevant CR and anisotropic transport processes in order to quantify the amount and distribution of heating from the AGN. Our

Multi-phase outflows as probes of AGN accretion history

NASA Astrophysics Data System (ADS)

Nardini, Emanuele; Zubovas, Kastytis

2018-05-01

Powerful outflows with a broad range of properties (such as velocity, ionization, radial scale and mass loss rate) represent a key feature of active galactic nuclei (AGN), even more so since they have been simultaneously revealed also in individual objects. Here we revisit in a simple analytical framework the recent remarkable cases of two ultraluminous infrared quasars, IRAS F11119+3257 and Mrk 231, which allow us to investigate the physical connection between multi-phase AGN outflows across the ladder of distance from the central supermassive black hole (SMBH). We argue that any major deviations from the standard outflow propagation models might encode unique information on the past SMBH accretion history, and briefly discuss how this could help address some controversial aspects of the current picture of AGN feedback.

Glomerular common gamma chain confers B- and T-cell-independent protection against glomerulonephritis.

PubMed

Luque, Yosu; Cathelin, Dominique; Vandermeersch, Sophie; Xu, Xiaoli; Sohier, Julie; Placier, Sandrine; Xu-Dubois, Yi-Chun; Louis, Kevin; Hertig, Alexandre; Bories, Jean-Christophe; Vasseur, Florence; Campagne, Fabien; Di Santo, James P; Vosshenrich, Christian; Rondeau, Eric; Mesnard, Laurent

2017-05-01

Crescentic glomerulonephritis is a life-threatening renal disease that has been extensively studied by the experimental anti-glomerular basement membrane glomerulonephritis (anti-GBM-GN) model. Although T cells have a significant role in this model, athymic/nude mice and rats still develop severe renal disease. Here we further explored the contribution of intrinsic renal cells in the development of T-cell-independent GN lesions. Anti-GBM-GN was induced in three strains of immune-deficient mice (Rag2 -/- , Rag2 -/- Il2rg -/- , and Rag2 -/- Il2rb -/- ) that are devoid of either T/B cells or T/B/NK cells. The Rag2 -/- Il2rg -/- or Rag2 -/- Il2rb -/- mice harbor an additional deletion of either the common gamma chain (γC) or the interleukin-2 receptor β subunit (IL-2Rβ), respectively, impairing IL-15 signaling in particular. As expected, all these strains developed severe anti-GBM-GN. Additionally, bone marrow replenishment experiments allowed us to deduce a protective role for the glomerular-expressed γC during anti-GBM-GN. Given that IL-15 has been found highly expressed in nephritic kidneys despite the absence of lymphocytes, we then studied this cytokine in vitro on primary cultured podocytes from immune-deficient mice (Rag2 -/- Il2rg -/- and Rag2 -/- Il2rb -/- ) compared to controls. IL-15 induced downstream activation of JAK1/3 and SYK in primary cultured podocytes. IL-15-dependent JAK/SYK induction was impaired in the absence of γC or IL-2Rβ. We found γC largely induced on podocytes during human glomerulonephritis. Thus, renal lesions are indeed modulated by intrinsic glomerular cells through the γC/IL-2Rβ receptor response, to date classically described only in immune cells. Copyright © 2016 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

AGN feedback through UFO and galaxy-wide winds in the early Universe

NASA Astrophysics Data System (ADS)

Feruglio, C.; Piconcelli, E.; Bischetti, M.; Zappacosta, L.; Fiore, F.

2017-10-01

AGN feedback through massive molecular winds is today routinely observed in local AGN host galaxies, but not as such in the early universe. I will present the first evidence for a massive, AGN-driven molecular wind in the z 4 QSO APM08279, which also hosts the most well studied and persistent nuclear semi-raltivistic wind (UFO). This observation directly probes the expansion mechanism of a nuclear wind into the ISM on galaxy wide scales, that so far was constrained by a couple of other objects only (Feruglio et al. 2015, Tombesi et al. 2015). This result also opens the path toward the exploration of molecular AGN-driven winds at early epochs, close after the end of the Epoch of Reionisation (EoR).

Quenching histories of galaxies and the role of AGN feedback

NASA Astrophysics Data System (ADS)

Smethurst, Rebecca Jane; Lintott, Chris; Simmons, Brooke; Galaxy Zoo Team

2016-01-01

Two open issues in modern astrophysics are: (i) how do galaxies fully quench their star formation and (ii) how is this affected - or not - by AGN feedback? I present the results of a new Bayesian-MCMC analysis of the star formation histories of over 126,000 galaxies across the colour magnitude diagram showing that diverse quenching mechanisms are instrumental in the formation of the present day red sequence. Using classifications from Galaxy Zoo we show that the rate at which quenching can occur is morphologically dependent in each of the blue cloud, green valley and red sequence. We discuss the nature of these possible quenching mechanisms, considering the influence of secular evolution, galaxy interactions and mergers, both with and without black hole activity. We focus particularly on the relationship between these quenched star formation histories and the presence of an AGN by using this new Bayesian method to show a population of type 2 AGN host galaxies have recently (within 2 Gyr) undergone a rapid (τ < 1 Gyr) drop in their star formation rate. With this result we therefore present the first statistically supported observational evidence that AGN feedback is an important mechanism for the cessation of star formation in this population of galaxies. The diversity of this new method also highlights that such rapid quenching histories cannot account fully for all the quenching across the current AGN host population. We demonstrate that slower (τ > 2 Gyr) quenching rates dominate for high stellar mass (log10[M*/M⊙] > 10.75) hosts of AGN with both early- and late-type morphology. We discuss how these results show that both merger-driven and non-merger processes are contributing to the co-evolution of galaxies and supermassive black holes across the entirety of the colour magnitude diagram.

Clustering, Cosmology and a New Era of Black Hole Demographics: The Conditional Luminosity Function of AGNs

NASA Astrophysics Data System (ADS)

Ballantyne, David R.

2017-01-01

Deep X-ray surveys have provided a comprehensive and largely unbiased view of active galactic nuclei (AGN) evolution stretching back to z~5. However, it has been challenging to use the survey results to connect this evolution to the cosmological environment that AGNs inhabit. Exploring this connection will be crucial to understanding the triggering mechanisms of AGNs and how these processes manifest in observations at all wavelengths. In anticipation of upcoming wide-field X-ray surveys that will allow quantitative analysis of AGN environments, we present a method to observationally constrain the Conditional Luminosity Function (CLF) of AGNs at a specific z. Once measured, the CLF allows the calculation of the AGN bias, mean dark matter halo mass, AGN lifetime, halo occupation number, and AGN correlation function -- all as a function of luminosity. The CLF can be constrained using a measurement of the X-ray luminosity function and the correlation length at different luminosities. The method is illustrated at z≈0 and 0.9 using the limited data that is currently available, and a clear luminosity dependence in the AGN bias and mean halo mass is predicted at both, supporting the idea that there are at least two different modes of AGN triggering. In addition, the CLF predicts that z≈0.9 quasars may be commonly hosted by haloes with Mh ~ 1014 M⊙. These `young cluster' environments may provide the necessary interactions between gas-rich galaxies to fuel luminous accretion. The results derived from this method will be useful to populate AGNs of different luminosities in cosmological simulations.

Non-blackbody Disks Can Help Explain Inferred AGN Accretion Disk Sizes

NASA Astrophysics Data System (ADS)

Hall, Patrick B.; Sarrouh, Ghassan T.; Horne, Keith

2018-02-01

If the atmospheric density {ρ }atm} in the accretion disk of an active galactic nucleus (AGN) is sufficiently low, scattering in the atmosphere can produce a non-blackbody emergent spectrum. For a given bolometric luminosity, at ultraviolet and optical wavelengths such disks have lower fluxes and apparently larger sizes as compared to disks that emit as blackbodies. We show that models in which {ρ }atm} is a sufficiently low fixed fraction of the interior density ρ can match the AGN STORM observations of NGC 5548 but produce disk spectral energy distributions that peak at shorter wavelengths than observed in luminous AGN in general. Thus, scattering atmospheres can contribute to the explanation for large inferred AGN accretion disk sizes but are unlikely to be the only contributor. In the appendix section, we present unified equations for the interior ρ and T in gas pressure-dominated regions of a thin accretion disk.

Clustering, Cosmology and a New Era of Black Hole Demographics: The Conditional Luminosity Function of AGNs

NASA Astrophysics Data System (ADS)

Ballantyne, David R.

2016-04-01

Deep X-ray surveys have provided a comprehensive and largely unbiased view of AGN evolution stretching back to z˜5. However, it has been challenging to use the survey results to connect this evolution to the cosmological environment that AGNs inhabit. Exploring this connection will be crucial to understanding the triggering mechanisms of AGNs and how these processes manifest in observations at all wavelengths. In anticipation of upcoming wide-field X-ray surveys that will allow quantitative analysis of AGN environments, we present a method to observationally constrain the Conditional Luminosity Function (CLF) of AGNs at a specific z. Once measured, the CLF allows the calculation of the AGN bias, mean dark matter halo mass, AGN lifetime, halo occupation number, and AGN correlation function - all as a function of luminosity. The CLF can be constrained using a measurement of the X-ray luminosity function and the correlation length at different luminosities. The method is demonstrated at z ≈0 and 0.9, and clear luminosity dependence in the AGN bias and mean halo mass is predicted at both z. The results support the idea that there are at least two different modes of AGN triggering: one, at high luminosity, that only occurs in high mass, highly biased haloes, and one that can occur over a wide range of halo masses and leads to luminosities that are correlated with halo mass. This latter mode dominates at z<0.9. The CLFs for Type 2 and Type 1 AGNs are also constrained at z ≈0, and we find evidence that unobscured quasars are more likely to be found in higher mass halos than obscured quasars. Thus, the AGN unification model seems to fail at quasar luminosities.

A comparative study of AGN feedback algorithms

NASA Astrophysics Data System (ADS)

Wurster, J.; Thacker, R. J.

2013-05-01

Modelling active galactic nuclei (AGN) feedback in numerical simulations is both technically and theoretically challenging, with numerous approaches having been published in the literature. We present a study of five distinct approaches to modelling AGN feedback within gravitohydrodynamic simulations of major mergers of Milky Way-sized galaxies. To constrain differences to only be between AGN feedback models, all simulations start from the same initial conditions and use the same star formation algorithm. Most AGN feedback algorithms have five key aspects: the black hole accretion rate, energy feedback rate and method, particle accretion algorithm, black hole advection algorithm and black hole merger algorithm. All models follow different accretion histories, and in some cases, accretion rates differ by up to three orders of magnitude at any given time. We consider models with either thermal or kinetic feedback, with the associated energy deposited locally around the black hole. Each feedback algorithm modifies the region around the black hole to different extents, yielding gas densities and temperatures within r ˜ 200 pc that differ by up to six orders of magnitude at any given time. The particle accretion algorithms usually maintain good agreement between the total mass accreted by dot{M} dt and the total mass of gas particles removed from the simulation, although not all algorithms guarantee this to be true. The black hole advection algorithms dampen inappropriate dragging of the black holes by two-body interactions. Advecting the black hole a limited distance based upon local mass distributions has many desirably properties, such as avoiding large artificial jumps and allowing the possibility of the black hole remaining in a gas void. Lastly, two black holes instantly merge when given criteria are met, and we find a range of merger times for different criteria. This is important since the AGN feedback rate changes across the merger in a way that is dependent

Morphology of AGN in the Central Kiloparsec

NASA Astrophysics Data System (ADS)

Martini, Paul

Hubble Space Telescope observations of the central kiloparsec of AGN have revealed a wealth of structure, particularly nuclear bars and spirals, that are distinct from analogous features in the disks of spiral galaxies. WFPC2 and NICMOS images of a large sample of AGN observed at high spatial resolution make it possible to quantify the frequency and detailed properties of these structures. Nearly all AGN have nuclear spiral dust lanes in the central kiloparsec, while only a small minority contain nuclear bars. If these nuclear dust spirals trace shocks in the circumnuclear, gaseous disks, they may dissipate sufficient angular momentum to fuel the active nucleus. I would like to thank my collaborators in this project---Rick Pogge, John Mulchaey, and Mike Regan---for allowing me to present this work in advance of publication, as well as Johan Knapen for organizing such an interesting meeting. Support for this work was provided by NASA through grant numbers GO-7867 and GO-8597 from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS5-26555.

Chandra and NuSTAR Follow-up Observations of Swift-BAT-selected AGNs

NASA Astrophysics Data System (ADS)

Marchesi, S.; Tremblay, L.; Ajello, M.; Marcotulli, L.; Paggi, A.; Cusumano, G.; La Parola, V.; Segreto, A.

2017-10-01

Based on current models of the cosmic X-ray background (CXB), heavily obscured active galactic nuclei (AGNs) are expected to make up ˜10% of the peak emission of the CXB and ˜20% of the total population of AGNs, yet few of these sources have been recorded and characterized in current surveys. Here we present the Chandra follow-up observation of 14 AGNs detected by Swift-BAT. For five sources in the sample, NuSTAR observations in the 3-80 keV band are also available. The X-ray spectral fitting over the 0.3-150 keV energy range allows us to determine the main X-ray spectral parameters, such as the photon index and the intrinsic absorption, of these objects and to make hypotheses on the physical structures responsible for the observed spectra. We find that 13 of the 14 objects are absorbed AGNs, and one is a candidate Compton-thick AGN, having intrinsic absorption {N}{{H}}> {10}24 cm-2. Finally, we verified that the use of NuSTAR observations is strategic to strongly constrain the properties of obscured AGNs, since the best-fit values we obtained for parameters such as the power-law photon index Γ and the intrinsic absorption {N}{{H}} changed sometimes significantly fitting the spectra with and without the use of NuSTAR data.

Understanding AGNs in the Local Universe through Optical Reverberation Mapping

NASA Astrophysics Data System (ADS)

Pei, Liuyi

2016-01-01

I present the results of observational projects aimed at measuring the mass of the black hole at the center of active galactic nuclei (AGNs) and understanding the structure and kinematics of the broad-line emitting gas within the black hole's sphere of influence.The first project aims to measure the black hole mass in the Kepler-field AGN KA1858. We obtained simultaneous spectroscopic data from the Lick Observatory 3-m telescope using the Kast Double Spectrograph and photometry data from five ground-based telescopes, and used reverberation mapping (RM) techniques to measure the emission-line light curves' lags relative to continuum variations. We obtained lags for H-beta, H-gamma, H-delta, and He II, and obtained the first black hole mass measurement for this object. Our results will serve as a reference point for future studies on relations between black hole mass and continuum variability characteristics using Kepler AGN light curves.The second project, in collaboration with the AGN STORM team, aims to understand the structure and dynamics of the broad line region (BLR) in NGC 5548 in both UV and optical wavelengths. To supplement 6 months of HST UV observations, we obtained simultaneous optical spectroscopic data from six ground-based observatories. We obtained emission-line lags for the optical H-beta and He II lines as well as velocity-resolved lag measurements for H-beta. We also compared the velocity-resolved lags for H-beta to the UV emission lines C IV and Ly-alpha and found similar lag profiles for all three lines.Finally, I will discuss my contributions to two other collaborations in AGN RM. A key component in RM is monitoring continuum variability, which is often done through ground-based photometry. I will present a pipeline that performs aperture photometry on any number of images of an AGN with WCS coordinates and immediately produces relative light curves. This pipeline enables quick looks of AGN variability in real time and has been used in the

THE HOST GALAXY PROPERTIES OF VARIABILITY SELECTED AGN IN THE PAN-STARRS1 MEDIUM DEEP SURVEY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heinis, S.; Gezari, S.; Kumar, S.

2016-07-20

We study the properties of 975 active galactic nuclei (AGNs) selected by variability in the Pan-STARRS1 Medium deep Survey. Using complementary multi-wavelength data from the ultraviolet to the far-infrared, we use spectral energy distribution fitting to determine the AGN and host properties at z < 1 and compare to a well-matched control sample. We confirm the trend previously observed: that the variability amplitude decreases with AGN luminosity, but we also observe that the slope of this relation steepens with wavelength, resulting in a “redder when brighter” trend at low luminosities. Our results show that AGNs are hosted by more massivemore » hosts than control sample galaxies, while the rest frame dust-corrected NUV r color distribution of AGN hosts is similar to control galaxies. We find a positive correlation between the AGN luminosity and star formation rate (SFR), independent of redshift. AGN hosts populate the entire range of SFRs within and outside of the Main Sequence of star-forming galaxies. Comparing the distribution of AGN hosts and control galaxies, we show that AGN hosts are less likely to be hosted by quiescent galaxies and more likely to be hosted by Main Sequence or starburst galaxies.« less

The Relation between Luminous AGNs and Star Formation in Their Host Galaxies

NASA Astrophysics Data System (ADS)

Xu, Lei; Rieke, G. H.; Egami, E.; Haines, C. P.; Pereira, M. J.; Smith, G. P.

2015-08-01

We study the relation of active galactic nuclei (AGNs) to star formation in their host galaxies. Our sample includes 205 Type-1 and 85 Type-2 AGNs, 162 detected with Herschel, from fields surrounding 30 galaxy clusters in the Local Cluster Substructure Survey. The sample is identified by optical line widths and ratios after selection to be brighter than 1 mJy at 24 μm. We show that Type-2 AGN [O iii]λ5007 line fluxes at high z can be contaminated by their host galaxies with typical spectrograph entrance apertures (but our sample is not compromised in this way). We use spectral energy distribution (SED) templates to decompose the galaxy SEDs and estimate star formation rates (SFRs), AGN luminosities, and host galaxy stellar masses (described in an accompanying paper). The AGNs arise from massive black holes (˜ 3× {10}8{M}⊙ ) accreting at ˜10% of the Eddington rate and residing in galaxies with stellar mass \\gt 3× {10}10{M}⊙ ; those detected with Herschel have IR luminosity from star formation in the range of {L}{SF,{IR}}˜ {10}10-{10}12{L}⊙ . We find that (1) the specific SFRs in the host galaxies are generally consistent with those of normal star-forming (main sequence) galaxies; (2) there is a strong correlation between the luminosities from star formation and the AGN; and (3) the correlation may not result from a causal connection, but could arise because the black hole mass (and hence AGN Eddington luminosity) and star formation are both correlated with the galaxy mass.

Unveiling the physics of AGN through X-ray variability

NASA Astrophysics Data System (ADS)

Hernández-García, L.; González-Martín, O.; Masegosa, J.; Márquez, I.

2017-03-01

Although variability is a general property characterizing active galactic nuclei (AGN), it is not well established whether the changes occur in the same way in every nuclei. The main purpose of this work is to study the X-ray variability pattern(s) in AGN selected at optical wavelengths in a large sample, including low ionization nuclear emission line regions (LINERs) and type 1.8, 1.9, and 2 Seyferts, using the public archives in Chandra and/or XMM-Newton. Spectra of the same source gathered at different epochs were simultaneously fitted to study long term variations; the variability patterns were studied allowing different parameters to vary during the spectral fit. Whenever possible, short term variations from the analysis of the light curves and long term UV flux variability were studied. Variations at X-rays in timescales of months/years are very common in all AGN families but short term variations are only found in type 1.8 and 1.9 Seyferts. The main driver of the long term X-ray variations seems to be related to changes in the nuclear power. Other variability patterns cannot be discarded in a few cases. We discuss the geometry and physics of AGN through the X-ray variability analysis.

Precision cosmology from X-ray AGN clustering

NASA Astrophysics Data System (ADS)

Basilakos, Spyros; Plionis, Manolis

2009-11-01

We place tight constraints on the main cosmological parameters of spatially flat cosmological models by using the recent angular clustering results of XMM-Newton soft (0.5-2keV) X-ray sources, which have a redshift distribution with a median of z ~ 1. Performing a standard likelihood procedure, assuming a constant in comoving coordinates active galactic nuclei (AGN) clustering evolution, the AGN bias evolution model of Basilakos, Plionis & Ragone-Figueroa and the Wilkinson Microwave Anisotropy Probe5 value of σ8, we find stringent simultaneous constraints in the (Ωm, w) plane, with Ωm = 0.26 +/- 0.05, w = -0.93+0.11-0.19.

Probing the gas fuelling and outflows in nearby AGN with ALMA

NASA Astrophysics Data System (ADS)

Audibert, Anelise; Combes, Françoise; García-Burillo, Santiago; Salomé, Philippe

2017-12-01

Feeding and feedback in AGN play a very important role to gain a proper understanding of galaxy formation and evolution. The interaction between activity mechanisms in the nucleus and its influence in the host galaxy are related to the physical processes involved in feedback and the gas fuelling of the black hole. The discovery of many massive molecular outflows in the last few years have been promoting the idea that winds may be major actors in sweeping the gas out of galaxies. Also, the widely observed winds from the central regions of AGN are promising candidates to explain the scaling relations (e.g. the black hole-bulge mass relation, BH accretion rate tracking the star formation history) under the AGN feedback scenario. Out goal is to probe these phenomena through the kinematic and morphology of the gas inside the central kpc in nearby AGN. This has recently been possible due to the unprecedented ALMA spatial resolution and sensitivity. We present results on NGC7213 and NGC1808, the latter is part of a new ALMA follow-up of the NuGa project, a previous high-resolution (0.5-1”) CO survey of low luminosity AGN performed with the IRAM PdBI.

Accretion Disk and Dust Emission in Low-Luminosity AGN

NASA Astrophysics Data System (ADS)

Biddle, Lauren I.; Mason, Rachel; Alonso-Herrero, Almudena; Colina, Luis; Diaz, Ruben; Flohic, Helene; Gonzalez-Martin, Omaira; Ho, Luis C.; Lira, Paulina; Martins, Lucimara; McDermid, Richard; Perlman, Eric S.; Ramos Almeida, Christina; Riffel, Rogerio; Ardila, Alberto; Ruschel Dutra, Daniel; Schiavon, Ricardo; Thanjavur, Karun; Winge, Claudia

2015-01-01

Observations obtained in the near-infrared (near-IR; 0.8 - 2.5 μm) can assist our understanding of the physical and evolutionary processes of galaxies. Using a set of near-IR spectra of nearby galaxies obtained with the cross-dispersed mode of GNIRS on the Gemini North telescope, we investigate how the accretion disk and hot dust emission depend on the luminosity of the active nucleus. We recover faint AGN emission from the starlight-dominated nuclear regions of the galaxies, and measure properties such as the spectral shape and luminosity of the accretion disk and dust. The aim of this work is to establish whether the standard thin accretion disk may be truncated in low-accretion-rate AGN, as well as evaluate whether the torus of the AGN unified model still exists at low luminosities.

Revisiting the `forbidden' region: AGN radiative feedback with radiation trapping

NASA Astrophysics Data System (ADS)

Ishibashi, W.; Fabian, A. C.; Ricci, C.; Celotti, A.

2018-06-01

Active galactic nucleus (AGN) feedback, driven by radiation pressure on dust, is an important mechanism for efficiently coupling the accreting black hole to the surrounding environment. Recent observations confirm that X-ray selected AGN samples respect the effective Eddington limit for dusty gas in the plane defined by the observed column density versus the Eddington ratio, the so-called NH - λ plane. A `forbidden' region occurs in this plane, where obscuring clouds cannot be long-lived, due to the action of radiation pressure on dust. Here we compute the effective Eddington limit by explicitly taking into account the trapping of reprocessed radiation (which has been neglected in previous works), and investigate its impact on the NH - λ plane. We show that the inclusion of radiation trapping leads to an enhanced forbidden region, such that even Compton-thick material can potentially be disrupted by sub-Eddington luminosities. We compare our model results to the most complete sample of local AGNs with measured X-ray properties, and find good agreement. Considering the anisotropic emission from the accretion disc, we also expect the development of dusty outflows along the polar axis, which may naturally account for the polar dust emission recently detected in several AGNs from mid-infrared observations. Radiative feedback thus appears to be the key mechanism regulating the obscuration properties of AGNs, and we discuss its physical implications in the context of co-evolution scenarios.

Crescentic Glomerulonephritis in a Polar Bear (Ursus maritimus)

PubMed Central

BABA, Hiroshi; KUDO, Tomoo; MAKINO, Yoshinori; MOCHIZUKI, Yasumasa; TAKAGI, Takayo; UNE, Yumi

2013-01-01

ABSTRACT Spontaneous crescentic glomerulonephritis (CrGN) in animals has only been reported in dog and sheep. We report the pathological features of CrGN in a 17-year-old male polar bear that died due to renal failure. Histologically, the lesions were characterized by fibrocellular crescents, adhesion between Bowman’s capsule and the glomerular capillary tuft and an increase in the mesangial matrix in glomeruli. The proliferating cells in the crescent were partly immunopositive for cytokeratin and intensely positive for vimentin, WT-1 and α-smooth muscle actin, suggesting they originated from parietal epithelial cells. Ultrastructually, thickening of the glomerular basement membrane and loss of epithelial cell foot processes were observed with electron-dense deposits. PMID:23856758

Crescentic glomerulonephritis in a polar bear (Ursus maritimus).

PubMed

Baba, Hiroshi; Kudo, Tomoo; Makino, Yoshinori; Mochizuki, Yasumasa; Takagi, Takayo; Une, Yumi

2013-11-01

Spontaneous crescentic glomerulonephritis (CrGN) in animals has only been reported in dog and sheep. We report the pathological features of CrGN in a 17-year-old male polar bear that died due to renal failure. Histologically, the lesions were characterized by fibrocellular crescents, adhesion between Bowman's capsule and the glomerular capillary tuft and an increase in the mesangial matrix in glomeruli. The proliferating cells in the crescent were partly immunopositive for cytokeratin and intensely positive for vimentin, WT-1 and α-smooth muscle actin, suggesting they originated from parietal epithelial cells. Ultrastructually, thickening of the glomerular basement membrane and loss of epithelial cell foot processes were observed with electron-dense deposits.

[Rapidly progressive glomerulonephritis: a diagnostic and therapeutic emergency].

PubMed

Halfon, Matthieu; Teta, Daniel; Rotman, Samuel; Pruijm, Menno; Humbert, Antoine

2014-02-26

Rapidly progressive glomerulonephritis (RPG) is a rare clinical syndrome characterized by kidney damage that can lead to irreversible kidney failure. RPG can be caused by primary glomerular disease or can be part of a systemic autoimmune disorder. All RPG have a similar pathophysiology (proliferation of cells in Bowman's capsule and formation of crescents) and clinical evolution (rapidly progressive kidney failure with proteinuria and an active urine sediment). Immunosuppressive therapy and sometimes plasma exchanges are required. Overall- and kidney survival are closely linked to the blood creatinine level at presentation, the percentage of damaged glomeruli, and to the underlying cause. RPG is therefore a diagnostic and therapeutic emergency that needs quick referral to a nephrologist.

Crescentic glomerulonephritis in non-asthmatic Churg-Strauss syndrome.

PubMed

Kaul, Anupma; Sharma, Raj Kumar; Jaisuresh, Krishna Swamy; Agrawal, Vinita

2014-03-01

A 58-year-old male presented with sensory motor polyneuropathy and rapidly progressive renal failure. Investigations revealed marked peripheral eosinophilia and elevated perinuclear antineutrophil cytoplasmic antibody titers. Renal biopsy showed pauci-immune cre-scentic glomerulonephritis with interstitial eosinophil infiltrates. He had no history of asthma. Computed tomography of the chest and X-ray of the paranasal sinuses were normal. On Day 1, the patient developed ileal perforation. Resected ileal segments showed small vessel vasculitis with extravascular eosinophils. A diagnosis of non-asthmatic variant of Churg-Strauss syndrome was made. Renal recovery was achieved in 12 weeks with a combination therapy of corticosteroid and cyclophosphamide. The patient has been relapse-free for 12 months on oral prednisolone therapy.

The SIX survey: evolution and properties of AGN in the local universe

NASA Astrophysics Data System (ADS)

Bottacini, Eugenio

2014-07-01

Current most sensitive surveys at soft X-ray (~ 0.5-10 keV) energies by Chandra and XMM-Newton preferably sample AGN at high-redshift (z > 0.5). At low-redshift (z < 0.5), where AGN are supposed to be in their evolution end-stage, these sources are very sparsely sampled. The low-redshift universe is best fathomed at hard X-ray energies (> 15 keV) by the INTEGRAL and the Swift missions with their coded-mask telescopes IBIS/ISGRI and BAT respectively. These instruments have two major advantages: 1) they have a huge field of view, hence allowing to sample a large number of AGN at low-redshift; 2) they operate at energies above 15 keV, hence allowing detecting photons with enough power to efficiently pierce even through the Compton-thick torus of AGN. Estimates based on observations with PDS on board the BeppoSAX satellite predict that Compton-thick AGN should dominate over unabsorbed AGN in the local universe playing an important role in reproducing the shape and intensity of the cosmic X-ray background (CXB). However coded-mask detectors suffer from heavy systematic effects preventing them from reaching their theoretical limiting sensitivity. We overcome this limit with a new and alternative approach, which has been designed ad hoc to improve the sensitivity of hard X-ray surveys by using IBIS/ISGRI and BAT. Both telescopes are so close in design that their observations can be combined to obtain a more sensitive survey. The observations are combined with resampling, merging, and cross-calibration techniques. We are able to sample limiting fluxes of the order of ~3.3 times 10-12 erg cm-2 s-1 in the 18-55 keV energy range. This is called the SIX survey, that stands for Swift-INTEGRAL X-ray survey. The SIX survey extends over a wide sky area of 6200 deg2 and it is used to obtain a persistent sample of faint AGN. The source number density (log N - log S) is a factor of 3 better than current parent surveys of BAT and IBIS/ISGRI alone. I will present a study of the

Flickering AGN can explain the strong circumgalactic O VI observed by COS-Halos

NASA Astrophysics Data System (ADS)

Oppenheimer, Benjamin D.; Segers, Marijke; Schaye, Joop; Richings, Alexander J.; Crain, Robert A.

2018-03-01

Proximity zone fossils (PZFs) are ionization signatures around recently active galactic nuclei (AGNs) where metal species in the circumgalactic medium remain overionized after the AGNs have shut off due to their long recombination time scales. We explore cosmological zoom hydrodynamic simulations, using the EAGLE (Evolution and Assembly of GaLaxies and their Environments) model paired with a non-equilibrium ionization and cooling module including time-variable AGN radiation to model PZFs around star-forming disc galaxies in the z ˜ 0.2 Universe. Previous simulations typically underestimated the O VI content of galactic haloes, but we show that plausible PZF models increase O VI column densities by 2 - 3 × to achieve the levels observed around COS-Halos star-forming galaxies out to 150 kpc. Models with AGN bolometric luminosities ≳ 1043.6erg s- 1, duty cycle fractions ≲ 10 per cent, and AGN lifetimes ≲ 106 yr are the most promising, because their supermassive black holes grow at the cosmologically expected rate and they mostly appear as inactive AGN, consistent with COS-Halos. The central requirement is that the typical star-forming galaxy hosted an active AGN within a time-scale comparable to the recombination time of a high metal ion, which for circumgalactic O VI is ≈107 yr. H I, by contrast, returns to equilibrium much more rapidly due to its low neutral fraction and does not show a significant PZF effect. O VI absorption features originating from PZFs appear narrow, indicating photoionization, and are often well aligned with lower metal ion species. PZFs are highly likely to affect the physical interpretation of circumgalactic high ionization metal lines if, as expected, normal galaxies host flickering AGN.

Merger-driven fueling of active galactic nuclei: Six dual and of AGNs discovered with Chandra and Hubble Space Telescope observations

DOE PAGES

Comerford, Julia M.; Pooley, David; Barrows, R. Scott; ...

2015-06-19

Dual active galactic nuclei (AGNs) and offset AGNs are kpc-scale separation supermassive black holes pairs created during galaxy mergers, where both or one of the black holes are AGNs, respectively. These dual and offset AGNs are valuable probes of the link between mergers and AGNs but are challenging to identify. Here we present Chandra/ACIS observations of 12 optically selected dual AGN candidates atmore » $$z\\lt 0.34$$, where we use the X-rays to identify AGNs. We also present Hubble Space Telescope/Wide Field Camera 3 observations of 10 of these candidates, which reveal any stellar bulges accompanying the AGNs. We discover a dual AGN system with separation $${\\rm \\Delta }x=2.2$$ kpc, where the two stellar bulges have coincident [O iii] λ5007 and X-ray sources. This system is an extremely minor merger (460:1) that may include a dwarf galaxy hosting an intermediate mass black hole. We also find six single AGNs, and five systems that are either dual or offset AGNs with separations $${\\rm \\Delta }x\\lt 10$$ kpc. Four of the six dual AGNs and dual/offset AGNs are in ongoing major mergers, and these AGNs are 10 times more luminous, on average, than the single AGNs in our sample. This hints that major mergers may preferentially trigger higher luminosity AGNs. Further, we find that confirmed dual AGNs have hard X-ray luminosities that are half of those of single AGNs at fixed [O III] λ5007 luminosity, on average. Lastly, this could be explained by high densities of gas funneled to galaxy centers during mergers, and emphasizes the need for deeper X-ray observations of dual AGN candidates.« less

Probing the Properties of AGN Clustering in the Local Universe with Swift-BAT

NASA Astrophysics Data System (ADS)

Powell, M.; Cappelluti, N.; Urry, M.; Koss, M.; Allevato, V.; Ajello, M.

2017-10-01

I present the benchmark measurement of AGN clustering in the local universe with the all-sky Swift-BAT survey. The hard X-ray selection (14-195 keV) allows for the detection of some of the most obscured AGN, providing the largest, most unbiased sample of local AGN to date. We derive for the first time the halo occupation distribution (HOD) of the sample in various bins of black hole mass, accretion rate, and obscuration. In doing so, we characterize the cosmic environment of growing supermassive black holes with unprecedented precision, and determine which black hole parameters depend on environment. We then compare our results to the current evolutionary models of AGN.

VizieR Online Data Catalog: Intrinsic far-IR SED of luminous AGNs (Lyu+, 2017)

NASA Astrophysics Data System (ADS)

Lyu, J.; Rieke, G. H.

2018-01-01

The range of currently proposed active galactic nucleus (AGN) far-infrared templates results in uncertainties in retrieving host galaxy information from infrared observations and also undermines constraints on the outer part of the AGN torus. We discuss how to test and reconcile these templates. Physically, the fraction of the intrinsic AGN IR-processed luminosity compared with that from the central engine should be consistent with the dust-covering factor. In addition, besides reproducing the composite spectral energy distributions (SEDs) of quasars, a correct AGN IR template combined with an accurate library of star-forming galaxy templates should be able to reproduce the IR properties of the host galaxies, such as the luminosity-dependent SED shapes and aromatic feature strengths. We develop tests based on these expected behaviors and find that the shape of the AGN intrinsic far-IR emission drops off rapidly starting at ~20μm and can be matched by an Elvis+ (1994, J/ApJS/95/1)-like template with a minor modification. Despite the variations in the near- to mid-IR bands, AGNs in quasars and Seyfert galaxies have remarkably similar intrinsic far-IR SEDs at λ~20-100μm, suggesting a similar emission character of the outermost region of the circumnuclear torus. The variations of the intrinsic AGN IR SEDs among the type-1 quasar population can be explained by the changing relative strengths of four major dust components with similar characteristic temperatures, and there is evidence for compact AGN-heated dusty structures at sub-kiloparsec scales in the far-IR. (3 data files).

New approaches to trials in glomerulonephritis.

PubMed

Craig, Jonathan C; Tong, Allison; Strippoli, Giovanni F M

2017-01-01

Randomized controlled trials are required to reliably identify interventions to improve the outcomes for people with glomerulonephritis (GN). Unfortunately, although easier, observational studies are inherently unreliable even though the findings of both study designs agree most of the time. Currently there are ∼790 trials in GN, but suboptimal design and reporting, together with small sample sizes, mean that they may not be reliable for decision making. If the history is somewhat bleak, the future looks bright, with recent initiatives to improve the quality, size and relevance of clinical trials in nephrology, including greater patient engagement, trial networks, core outcome sets, registry-based trials and adaptive designs. Given the current state of the evidence informing the care of people with GN, disruptive technologies and pervasive culture change is required to ensure that the potential of trials to improve the health of people with this complex condition is to be realized. © The Author 2017. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

Mid-IR Properties of an Unbiased AGN Sample of the Local Universe. 1; Emission-Line Diagnostics

NASA Technical Reports Server (NTRS)

Weaver, K. A.; Melendez, M.; Muhotzky, R. F.; Kraemer, S.; Engle, K.; Malumuth. E.; Tueller, J.; Markwardt, C.; Berghea, C. T.; Dudik, R. P.;

AGN POPULATION IN HICKSON COMPACT GROUPS. I. DATA AND NUCLEAR ACTIVITY CLASSIFICATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

MartInez, M. A.; Del Olmo, A.; Perea, J.

2010-03-15

We have conducted a new spectroscopic survey to characterize the nature of nuclear activity in Hickson compact group (HCG) galaxies and establish its frequency. We have obtained new intermediate-resolution optical spectroscopy for 200 member galaxies and corrected for underlying stellar population contamination using galaxy templates. Spectra for 11 additional galaxies have been acquired from the ESO and 6dF public archives, and emission-line ratios have been taken from the literature for 59 more galaxies. Here we present the results of our classification of the nuclear activity for 270 member galaxies, which belong to a well-defined sample of 64 HCGs. We foundmore » a large fraction of galaxies, 63%, with emission lines. Using standard diagnostic diagrams, 45% of the emission-line galaxies were classified as pure active galactic nuclei (AGNs), 23% as Transition Objects (TOs), and 32% as star-forming nuclei (SFNs). In the HCGs, the AGN activity appears as the most frequent activity type. Adopting the interpretation that in TOs a low-luminosity AGN coexists with circumnuclear star formation, the fraction of galaxies with an AGN could rise to 42% of the whole sample. The low frequency (20%) of SFNs confirms that there is no star formation enhancement in HCGs. After extinction correction, we found a median AGN H{alpha} luminosity of 7.1 x 10{sup 39} erg s{sup -1}, which implies that AGNs in HCG have a characteristically low luminosity. This result added to the fact that there is an almost complete absence of broad-line AGNs in compact groups (CGs) as found by MartInez et al. and corroborated in this study for HCGs, is consistent with very few gas left in these galaxies. In general, therefore, what may characterize the level of activity in CGs is a severe deficiency of gas.« less

SWIFT BAT Survey of AGN

NASA Technical Reports Server (NTRS)

Tueller, J.; Mushotzky, R. F.; Barthelmy, S.; Cannizzo, J. K.; Gehrels, N.; Markwardt, C. B.; Skinner, G. K.; Winter, L. M.

2008-01-01

We present the results1 of the analysis of the first 9 months of data of the Swift BAT survey of AGN in the 14-195 keV band. Using archival X-ray data or follow-up Swift XRT observations, we have identified 129 (103 AGN) of 130 objects detected at [b] > 15deg and with significance > 4.8-delta. One source remains unidentified. These same X-ray data have allowed measurement of the X-ray properties of the objects. We fit a power law to the logN - log S distribution, and find the slope to be 1.42+/-0.14. Characterizing the differential luminosity function data as a broken power law, we find a break luminosity logL*(ergs/s)= 43.85+/-0.26. We obtain a mean photon index 1.98 in the 14-195 keV band, with an rms spread of 0.27. Integration of our luminosity function gives a local volume density of AGN above 10(exp 41) erg/s of 2.4x10(exp -3) Mpc(sup -3), which is about 10% of the total luminous local galaxy density above M* = -19.75. We have obtained X-ray spectra from the literature and from Swift XRT follow-up observations. These show that the distribution of log nH is essentially flat from nH = 10(exp 20)/sq cm to 10(exp 24)/sq cm, with 50% of the objects having column densities of less than 10(exp 22)/sq cm. BAT Seyfert galaxies have a median redshift of 0.03, a maximum log luminosity of 45.1, and approximately half have log nH > 22.

2MASS J00423991+3017515: An AGN On The Run?

NASA Astrophysics Data System (ADS)

Hogg, James

2016-10-01

We have discovered a peculiar AGN, 2MASS J00423991+3017515, in a local (z=0.14), disturbed galaxy whose optical spectrum has multiple broad lines that are consistently offset from the narrow line emission and host galaxy absorption by 1530 km/s. The morphology of the host galaxy and spectral properties thus suggest this AGN may be a recoiling supermassive black hole (SMBH). Gravitational-wave recoil kicks result from the coalescence of two SMBHs and have implications for the early growth of high-redshift quasars and SMBH-galaxy co-evolution. We propose high-resolution imaging in the NIR, optical, and UV with the WFC3 camera on Hubble and high-resolution X-ray imaging and spectral follow-ups with the ACIS camera on Chandra to determine if the source of the kinematically-offset broad line emission is also spatially offset from the nucleus of the host galaxy. We request 3 orbits with Hubble and 8 ksec with Chandra to conduct these follow-up observations. If a single, spatially offset AGN is detected, this source will be strongest candidate for a recoiling AGN candidate discovered to date, providing a new, indirect constraint on SMBH spin evolution and merger rates.

Star Formation and AGN Activity in Ultraluminous Infrared Galaxies at z > 1.15

NASA Astrophysics Data System (ADS)

Baldassare, Vivienne; Kartaltepe, J.

2012-01-01

We studied active galactic nucleus (AGN) activity and star formation in a sample of 52 luminous and ultraluminous infrared galaxies ((U)LIRGs) with 1.17 < z < 1.602 and LIR > 1011.5 Lsolar. ULIRGs get their extreme infrared luminosities from the heating of dust by star formation and/or AGN. Studies done in the local universe have revealed that all local ULIRGs are mergers (Sanders & Mirabel 1996), and have proposed evolutionary schemes in which early merger stages are dominated by starbursts, intermediate merger stages are dominated by starburst-AGN composite objects, and late merger stages are dominated by AGN (Yuan et al. 2010). They have also shown that most ULIRGs with LIR > 1012.4-12.5 Lsolar appear AGN-like (Tran et al. 2001). We used near infrared spectroscopy in order to determine whether these trends extend to high redshift, utilizing the [NII]/H-alpha and [OIII]/H-beta line ratios to plot our objects on a BPT diagram which classifies them as star forming, AGN, or composite. We find that many of the objects in our sample show evidence of mergers or interactions, and that all objects in our sample with LIR >1012.5 Lsolar are AGN or composite objects. Vivienne Baldassare was supported by the NOAO/KPNO Research Experiences for Undergraduates (REU) Program which is funded by the National Science Foundation Research Experiences for Undergraduates Program and the Department of Defense ASSURE program through Scientific Program Order No. 13 (AST-0754223) of the Cooperative Agreement No. AST-0132798 between the Association of Universities for Research in Astronomy (AURA) and the NSF.

Binary Black Holes, Accretion Disks and Relativistic Jets: Photocenters of Nearby AGN and Quasars

NASA Technical Reports Server (NTRS)

Wehrle, Ann E.; Jones, Dayton L.; Meier, David L.; Piner, B. Glenn; Unwin, Stephen C.

2004-01-01

One of the most challenging questions in astronomy today is to understand the origin, structure, and evolution of the central engines in the nuclei of quasars and active galaxies (AGNs). The favoured theory involves the activation of relativistic jets from the fueling of a supermassive black hole through an accretion disk. In some AGN an outer optically thick, dusty torus is seen orbiting the black hole system. This torus is probably related to an inner accretion disk - black hole system that forms the actual powerhouse of the AGN. In radio-loud AGN two oppositely-directed radio jets are ejected perpendicular to the torus/disk system. Although there is a wealth of observational data on AGN, some very basic questions have not been definitively answered. The Space Interferometry Mission (SIM) will address the following three key questions about AGN. 1) Does the most compact optical emission from an AGN come from an accretion disk or from a relativistic jet? 2) Does the separation of the radio core and optical photocenter of the quasars used for the reference frame tie, change on the timescales of their photometric variability, or is the separation stable at the level of a few microarcseconds? 3) Do the cores of galaxies harbor binary supermassive black holes remaining from galaxy mergers? It is not known whether such mergers are common, and whether binaries would persist for a significant time.

The redshift evolution of major merger triggering of luminous AGNs: a slight enhancement at z ˜ 2

NASA Astrophysics Data System (ADS)

Hewlett, Timothy; Villforth, Carolin; Wild, Vivienne; Mendez-Abreu, Jairo; Pawlik, Milena; Rowlands, Kate

2017-09-01

Active galactic nuclei (AGNs), particularly the most luminous AGNs, are commonly assumed to be triggered through major mergers; however, observational evidence for this scenario is mixed. To investigate any influence of galaxy mergers on AGN triggering and luminosities through cosmic time, we present a sample of 106 luminous X-ray-selected type 1 AGNs from the COSMOS survey. These AGNs occupy a large redshift range (0.5 < z < 2.2) and two orders of magnitude in X-ray luminosity (˜1043-1045 erg s-1). AGN hosts are carefully mass and redshift matched to 486 control galaxies. A novel technique for identifying and quantifying merger features in galaxies is developed, subtracting galfit galaxy models and quantifying the residuals. Comparison to visual classification confirms this measure reliably picks out disturbance features in galaxies. No enhancement of merger features with increasing AGN luminosity is found with this metric, or by visual inspection. We analyse the redshift evolution of AGNs associated with galaxy mergers and find no merger enhancement in lower redshift bins. Contrarily, in the highest redshift bin (z ˜ 2) AGNs are ˜4 times more likely to be in galaxies exhibiting evidence of morphological disturbance compared to control galaxies, at 99 per cent confidence level (˜2.4σ) from visual inspection. Since only ˜15 per cent of these AGNs are found to be in morphologically disturbed galaxies, it is implied that major mergers at high redshift make a noticeable but subdominant contribution to AGN fuelling. At low redshifts, other processes dominate and mergers become a less significant triggering mechanism.

Host Galaxies Of Luminous Z ˜ 0.6 Quasars: Major Mergers Are Not Prevalent At The Highest Agn Luminosities

NASA Astrophysics Data System (ADS)

Villforth, Carolin; Hamilton, T.; Pawlik, M. M.; Hewlett, T.; Rowlands, K.; Herbst, H.; Shankar, F.; Fontana, A.; Hamann, F.; Koekemoer, A.; Pforr, J.; Trump, J.; Wuyts, S.

2017-06-01

Galaxy interactions are thought to be one of the main triggers of active galactic nuclei (AGN), especially at high luminosities, where the accreted gas mass during the AGN lifetime is substantial. Evidence for a connection between mergers and AGN, however, remains mixed. Possible triggering mechanisms remain particularly poorly understood for luminous AGN, which are thought to require triggering by major mergers, rather than secular processes. We analyse the host galaxies of a sample of 20 optically and X-ray selected luminous AGN (log(Lbol [erg s-1]) > 45) at z ˜ 0.6 using Hubble Space Telescope Wide Field Camera 3 data in the F160W/H band. 15/20 sources have resolved host galaxies. We create a control sample of mock AGN by matching the AGN host galaxies to a control sample of non-AGN galaxies. Visual signs of disturbances are found in about 25 per cent of sources in both the AGN hosts and control galaxies. Using both visual classification and quantitative morphology measures, we show that the levels of disturbance are not enhanced when compared to a matched control sample. We find no signs that major mergers play a dominant role in triggering AGN at high luminosities, suggesting that minor mergers and secular processes dominate AGN triggering up to the highest AGN luminosities. The upper limit on the enhanced fraction of major mergers is ≤20 per cent. While major mergers might increase the incidence of luminous AGN, they are not the prevalent triggering mechanism in the population of unobscured AGN.

Host galaxies of luminous z ˜ 0.6 quasars: major mergers are not prevalent at the highest AGN luminosities

NASA Astrophysics Data System (ADS)

Villforth, C.; Hamilton, T.; Pawlik, M. M.; Hewlett, T.; Rowlands, K.; Herbst, H.; Shankar, F.; Fontana, A.; Hamann, F.; Koekemoer, A.; Pforr, J.; Trump, J.; Wuyts, S.

2017-04-01

Galaxy interactions are thought to be one of the main triggers of active galactic nuclei (AGN), especially at high luminosities, where the accreted gas mass during the AGN lifetime is substantial. Evidence for a connection between mergers and AGN, however, remains mixed. Possible triggering mechanisms remain particularly poorly understood for luminous AGN, which are thought to require triggering by major mergers, rather than secular processes. We analyse the host galaxies of a sample of 20 optically and X-ray selected luminous AGN (log(Lbol [erg s-1]) > 45) at z ˜ 0.6 using Hubble Space Telescope Wide Field Camera 3 data in the F160W/H band. 15/20 sources have resolved host galaxies. We create a control sample of mock AGN by matching the AGN host galaxies to a control sample of non-AGN galaxies. Visual signs of disturbances are found in about 25 per cent of sources in both the AGN hosts and control galaxies. Using both visual classification and quantitative morphology measures, we show that the levels of disturbance are not enhanced when compared to a matched control sample. We find no signs that major mergers play a dominant role in triggering AGN at high luminosities, suggesting that minor mergers and secular processes dominate AGN triggering up to the highest AGN luminosities. The upper limit on the enhanced fraction of major mergers is ≤20 per cent. While major mergers might increase the incidence of luminous AGN, they are not the prevalent triggering mechanism in the population of unobscured AGN.

FOUR DUAL AGN CANDIDATES OBSERVED WITH THE VLBA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gabányi, K. É.; Frey, S.; An, T.

According to hierarchical structure formation models, merging galaxies are expected to be seen in different stages of coalescence. However, there are currently no straightforward observational methods to either select or to confirm a large number of dual active galactic nucleus (AGN) candidates. Most attempts involve obtaining a better understanding of double-peaked narrow emission line sources, in order to distinguish the objects for which the emission lines originate from narrow-line kinematics or jet-driven outflows, from those which might harbor dual AGNs. We observed four such candidate sources with the Very Long Baseline Array (VLBA), at 1.5 GHz with a ∼10 masmore » angular resolution, for which the spectral profiles of AGN optical emission suggested the existence of dual AGNs. In SDSS J210449.13–000919.1 and SDSS J23044.82–093345.3 the radio structures are aligned with the optical emission features, thus the double-peaked emission lines might be the results of jet-driven outflows. In the third detected source SDSS J115523.74+150756.9, the radio structure is less extended and is oriented nearly perpendicular to the position angle derived from optical spectroscopy. The fourth source remained undetected with the VLBA, but it was imaged with the Very Large Array at arcsec resolution a few months before our observations, suggesting the existence of an extended radio structure. We did not detect two radio-emitting cores in any of the four sources, a convincing signature of duality.« less

Review of Space VLBI RadioAstron studies of AGN

NASA Astrophysics Data System (ADS)

Gurvits, Leonid; Kovalev, Yuri

2016-07-01

Space VLBI offers an unrivalled resolution in studies of the AGN phenomena. Since 2011, the Russia-led SVLBI mission RadioAstron conducts observations at 92, 18, 6 and 1.3 cm with baselines an order of magnitude longer than the Earth diameter, therefore offering an order of magnitude "sharper" view at the brightest radio sources than achieved with Earth-based VLBI systems. In our presentation we will review the current status of the RadioAstron's scientific programme. Over the first 4.5 years of the in-orbit operations, the mission achieved successful VLBI detections of extragalactic continuum radio sources at all four observing bands. To date, detections on SVLBI baselines have been obtained for more than 150 AGN's at projected baselines up to 350 000 km (about 28 Earth diameters, ED). The highest resolution achieved is 14 microarcscends from 1.3 cm observations. RadioAstron is an international project; it conducts observations with up to 30 Earth-based radio telescopes located on different continents. We will review results of total intensity and polarisation imaging with extreme angular resolution of blazars and nearby active galaxies. We will also discuss typical and maximum brightness temperatures of blazar cores from the AGN Survey obtained with RadioAstron. Physical implications for the AGN jets formation, magnetic field and emission mechanism will be discussed on the basis of the results obtained to date.

Fibrillary glomerulonephritis associated with monoclonal gammopathy of undetermined significance showing lambda-type Bence Jones protein.

PubMed

Nagao, Tomoaki; Okura, Takafumi; Miyoshi, Ken-Ichi; Watanabe, Sanae; Manabe, Seiko; Kurata, Mie; Irita, Jun; Fukuoka, Tomikazu; Higaki, Jitsuo

2005-09-01

A 79-year-old woman was admitted to our hospital because of leg edema due to a nephrotic syndrome. Urinary and serum immunoelectrophoresis showed positive for the lambda type of Bence Jones protein. A bone marrow aspiration test revealed mild plasmacytosis (6.4% of the total cells). These findings confirmed her diagnosis of monoclonal gammopathy of undetermined significance (MGUS). Her renal biopsy specimen revealed mild mesangial cell proliferation and an increase in the mesangial matrix. Immunofluorescence studies showed positive staining for IgG, IgA, C3, and kappa and lambda light chains in the capillary wall and mesangium area. Electron microscopy showed that the electron deposits in the thickened basement membrane were formed by randomly arranged 16- to 18-nm nonbranching fibrils. A Congo red stain for amyloid was negative. These findings corresponded with the diagnosis of fibrillary glomerulonephritis. Therefore, this case showed a rare combination of fibrillary glomerulonephritis and MGUS.

On the Importance of Very Light Internally Subsonic AGN Jets in Radio-mode AGN Feedback

NASA Astrophysics Data System (ADS)

Guo, Fulai

2016-07-01

Radio-mode active galactic nucleus (AGN) feedback plays a key role in the evolution of galaxy groups and clusters. Its physical origin lies in the kiloparsec-scale interaction of AGN jets with the intracluster medium. Large-scale jet simulations often initiate light internally supersonic jets with density contrast 0.01 < η < 1. Here we argue for the first time for the importance of very light (η < 0.01) internally subsonic jets. We investigated the shapes of young X-ray cavities produced in a suite of hydrodynamic simulations, and found that bottom-wide cavities are always produced by internally subsonic jets, while internally supersonic jets inflate cylindrical, center-wide, or top-wide cavities. We found examples of real cavities with shapes analogous to those inflated in our simulations by internally subsonic and internally supersonic jets, suggesting a dichotomy of AGN jets according to their internal Mach numbers. We further studied the long-term cavity evolution, and found that old cavities resulted from light jets spread along the jet direction, while those produced by very light jets are significantly elongated along the perpendicular direction. The northwestern ghost cavity in Perseus is pancake shaped, providing tentative evidence for the existence of very light jets. Our simulations show that very light internally subsonic jets decelerate faster and rise much slower in the intracluster medium than light internally supersonic jets, possibly depositing a larger fraction of jet energy to cluster cores and alleviating the problem of low coupling efficiencies found previously. The internal Mach number points to the jet’s energy content, and internally subsonic jets are energetically dominated by non-kinetic energy, such as thermal energy, cosmic rays, or magnetic fields.

Acute glomerular upregulation of ornithine decarboxylase is not essential for mesangial cell proliferation and matrix expansion in anti-Thy-1-nephritis.

PubMed

Ketteler, M; Westenfeld, R; Gawlik, A; de Heer, E; Distler, A

2000-01-01

Pathways of L-arginine metabolism including nitric oxide, agmatine and polyamine synthesis are upregulated during glomerular inflammation in experimental glomerulonephritis. In anti-Thy-1-glomerulonephritis L-arginine-deficient diets ameliorate the disease course in this model. However, it is unclear which metabolic pathway is affected by this substrate depletion. Since polyamines are important proproliferative molecules, we studied the effect of specific polyamine synthesis blockade in vivo on mesangial cell proliferation and glomerular fibrosis in this model. Anti-Thy-1-glomerulonephritis was induced in male Sprague-Dawley rats by single-bolus injection of monoclonal ER4-antibodies. Rats were treated with difluoromethylornithine (0.5-2% in the drinking water), a selective inhibitor of the rate-limiting enzyme of polyamine synthesis, ornithine decarboxylase (ODC). Mesangial cell proliferation and matrix expansion were evaluated in PAS-stained kidney tissues. Glomerular TGF-beta and biglycan-mRNA-expression were determined by Northern blot analysis and albuminuria was measured using a competitive ELISA. Data were compared to untreated controls. Though complete inhibition of ODC activity was achieved at any time point, difluoromethlornithine treatment had no significant effect on albuminuria, glomerular matrix protein expression and mesangial cell count in this model. The acute upregulation of glomerular ODC activity above baseline in anti-Thy1-glomerulonephritis is not pathophysiologically important for disease development however, biological effects of available polyamine pools cannot be excluded by our study.

The 5-10 keV AGN luminosity function at 0.01 < z < 4.0

NASA Astrophysics Data System (ADS)

Fotopoulou, S.; Buchner, J.; Georgantopoulos, I.; Hasinger, G.; Salvato, M.; Georgakakis, A.; Cappelluti, N.; Ranalli, P.; Hsu, L. T.; Brusa, M.; Comastri, A.; Miyaji, T.; Nandra, K.; Aird, J.; Paltani, S.

2016-03-01

The active galactic nuclei (AGN) X-ray luminosity function traces actively accreting supermassive black holes and is essential for the study of the properties of the AGN population, black hole evolution, and galaxy-black hole coevolution. Up to now, the AGN luminosity function has been estimated several times in soft (0.5-2 keV) and hard X-rays (2-10 keV). AGN selection in these energy ranges often suffers from identification and redshift incompleteness and, at the same time, photoelectric absorption can obscure a significant amount of the X-ray radiation. We estimate the evolution of the luminosity function in the 5-10 keV band, where we effectively avoid the absorbed part of the spectrum, rendering absorption corrections unnecessary up to NH ~ 1023 cm-2. Our dataset is a compilation of six wide, and deep fields: MAXI, HBSS, XMM-COSMOS, Lockman Hole, XMM-CDFS, AEGIS-XD, Chandra-COSMOS, and Chandra-CDFS. This extensive sample of ~1110 AGN (0.01 < z < 4.0, 41 < log Lx < 46) is 98% redshift complete with 68% spectroscopic redshifts. For sources lacking a spectroscopic redshift estimation we use the probability distribution function of photometric redshift estimation specifically tuned for AGN, and a flat probability distribution function for sources with no redshift information. We use Bayesian analysis to select the best parametric model from simple pure luminosity and pure density evolution to more complicated luminosity and density evolution and luminosity-dependent density evolution (LDDE). We estimate the model parameters that describe best our dataset separately for each survey and for the combined sample. We show that, according to Bayesian model selection, the preferred model for our dataset is the LDDE. Our estimation of the AGN luminosity function does not require any assumption on the AGN absorption and is in good agreement with previous works in the 2-10 keV energy band based on X-ray hardness ratios to model the absorption in AGN up to redshift three

Effects on the optical properties and conductivity of Ag-N co-doped ZnO

NASA Astrophysics Data System (ADS)

Xu, Zhenchao; Hou, Qingyu; Qu, Lingfeng

2017-01-01

Nowadays, the studies of the effects on the optical bandgap, absorption spectrum, and electrical properties of Ag-N co-doped ZnO have been extensively investigated. However, Ag and N atoms in doped systems are randomly doped, and the asymmetric structure of ZnO is yet to be explored. In this paper, the geometric structure, stability, density of states, absorption spectra and conductivity of pure and Ag-N co-doped Zn1-xAgxO1-xNx(x=0.03125, 0.0417 and 0.0625) in different orientations are calculated by using plane-wave ultrasoft pseudopotential on the basis of density functional theory with GGA+U method. Results show that the volume, equivalent total energy and formation energy of the doped system increase as the concentration of Ag-N co-doped Zn1-xAgxO1-xNx increases at the same doping mode. The doped systems also become unstable, and difficulty in doping. At the same concentration of Ag-N co-doped Zn1-xAgxO1-xNx, the systems with Ag-N along the c-axis orientation is unstable, and doping is difficult. The optical bandgap of Ag-N co-doped systems is narrower than that of the pure ZnO. At the same doping mode, the optical bandgap of the systems with Ag-N perpendicular to the c-axis orientation becomes narrow as the concentration of Ag-N co-doped Zn1-xAgxO1-xNx increases. The absorption spectra of the doped systems exhibit a red shift, and this red shift becomes increasingly significant as the concentration of Ag-N co-doped Zn1-xAgxO1-xNx increases. Under the same condition, the relative hole concentrations of the doped systems increases, the hole effective mass in valence band maximum decreases, the hole mobility decreases, the ionization energy decreases, Bohr radius increases, the conductance increases and the conductivity become better. Our results may be used as a basis for the designing and preparation of new optical and electrical materials for Ag-N co-doped ZnO applied in low temperature end of temperature difference battery.

Characterisation of the macrophage transcriptome in glomerulonephritis-susceptible and -resistant rat strains

PubMed Central

Maratou, Klio; Behmoaras, Jacques; Fewings, Chris; Srivastava, Prashant; D’Souza, Zelpha; Smith, Jennifer; Game, Laurence; Cook, Terence; Aitman, Tim

2010-01-01

Crescentic glomerulonephritis (CRGN) is a major cause of rapidly progressive renal failure for which the underlying genetic basis is unknown. WKY rats show marked susceptibility to CRGN, while Lewis rats are resistant. Glomerular injury and crescent formation are macrophage-dependent and mainly explained by seven quantitative trait loci (Crgn1-7). Here, we used microarray analysis in basal and lipopolysaccharide (LPS)-stimulated macrophages to identify genes that reside on pathways predisposing WKY rats to CRGN. We detected 97 novel positional candidates for the uncharacterised Crgn3-7. We identified 10 additional secondary effector genes with profound differences in expression between the two strains (>5-fold change, <1% False Discovery Rate) for basal and LPS-stimulated macrophages. Moreover, we identified 8 genes with differentially expressed alternatively spliced isoforms, by using an in depth analysis at probe-level that allowed us to discard false positives due to polymorphisms between the two rat strains. Pathway analysis identified several common linked pathways, enriched for differentially expressed genes, which affect macrophage activation. In summary, our results identify distinct macrophage transcriptome profiles between two rat strains that differ in susceptibility to glomerulonephritis, provide novel positional candidates for Crgn3-7, and define groups of genes that play a significant role in differential regulation of macrophage activity. PMID:21179115

The invisible AGN catalogue: a mid-infrared-radio selection method for optically faint active galactic nuclei

NASA Astrophysics Data System (ADS)

Truebenbach, Alexandra E.; Darling, Jeremy

2017-06-01

A large fraction of active galactic nuclei (AGN) are 'invisible' in extant optical surveys due to either distance or dust-obscuration. The existence of this large population of dust-obscured, infrared (IR)-bright AGN is predicted by models of galaxy-supermassive black hole coevolution and is required to explain the observed X-ray and IR backgrounds. Recently, IR colour cuts with Wide-field Infrared Survey Explorer have identified a portion of this missing population. However, as the host galaxy brightness relative to that of the AGN increases, it becomes increasingly difficult to differentiate between IR emission originating from the AGN and from its host galaxy. As a solution, we have developed a new method to select obscured AGN using their 20-cm continuum emission to identify the objects as AGN. We created the resulting invisible AGN catalogue by selecting objects that are detected in AllWISE (mid-IR) and FIRST (20 cm), but are not detected in SDSS (optical) or 2MASS (near-IR), producing a final catalogue of 46 258 objects. 30 per cent of the objects are selected by existing selection methods, while the remaining 70 per cent represent a potential previously unidentified population of candidate AGN that are missed by mid-IR colour cuts. Additionally, by relying on a radio continuum detection, this technique is efficient at detecting radio-loud AGN at z ≥ 0.29, regardless of their level of dust obscuration or their host galaxy's relative brightness.

Star formation in AGNs at the hundred parsec scale using MIR high-resolution images

NASA Astrophysics Data System (ADS)

Ruschel-Dutra, Daniel; Rodríguez Espinosa, José Miguel; González Martín, Omaira; Pastoriza, Miriani; Riffel, Rogério

2017-04-01

It has been well established in the past decades that the central black hole masses of galaxies correlate with dynamical properties of their harbouring bulges. This notion begs the question of whether there are causal connections between the active galactic nucleus (AGN) and its immediate vicinity in the host galaxy. In this paper, we analyse the presence of circumnuclear star formation in a sample of 15 AGN using mid-infrared observations. The data consist of a set of 11.3 μm polycyclic aromatic hydrocarbon emission and reference continuum images, taken with ground-based telescopes, with sub-arcsecond resolution. By comparing our star formation estimates with AGN accretion rates, derived from X-ray luminosities, we investigate the validity of theoretical predictions for the AGN-starburst connection. Our main results are: (I) circumnuclear star formation is found, at distances as low as tens of parsecs from the nucleus, in nearly half of our sample (7/15); (II) star formation luminosities are correlated with the bolometric luminosity of the AGN (LAGN) only for objects with LAGN ≥ 1042 erg s-1; (III) low-luminosity AGNs (LAGN < 1042 erg s-1) seem to have starburst luminosities far greater than their bolometric luminosities.

Host Galaxy Morphologies Of Hard X-ray Selected AGN From The Swift BAT Survey

NASA Astrophysics Data System (ADS)

Koss, Michael; Mushotzky, R.; Veilleux, S.

2009-01-01

Surveys of AGN taken in the optical, UV, and soft X-rays miss an important population of obscured AGN only visible in the hard X-rays and mid-IR wavelengths. The SWIFT BAT survey in the hard X-ray range (14-195 keV) has provided a uniquely unbiased sample of 258 AGN unaffected by galactic or circumnuclear absorption. Optical imaging of this unbiased sample provides a new opportunity to understand how the environments of the host galaxies are linked to AGN. For these host galaxies, only a fraction, 29%, have high quality optical images, predominately from the SDSS. In addition, about 33% show peculiar morphologies and interaction. In 2008, we observed 110 of these targets at Kitt Peak with the 2.1m in the SDSS bands over 17 nights. Using these observations and SDSS data we review the relationships between color, morphology, merger activity, star formation, and AGN luminosity.

NuSTAR constraints on coronal cutoffs in Swift-BAT selected Seyfert 1 AGN

NASA Astrophysics Data System (ADS)

Kamraj, Nikita; Harrison, Fiona; Balokovic, Mislav; Brightman, Murray; Stern, Daniel

2017-08-01

The continuum X-ray emission from Active Galactic Nuclei (AGN) is believed to originate in a hot, compact corona above the accretion disk. Compton upscattering of UV photons from the inner accretion disk by coronal electrons produces a power law X-ray continuum with a cutoff at energies determined by the electron temperature. The NuSTAR observatory, with its high sensitivity in hard X-rays, has enabled detailed broadband modeling of the X-ray spectra of AGN, thereby allowing tight constraints to be placed on the high-energy cutoff of the X-ray continuum. Recent detections of low cutoff energies in Seyfert 1 AGN in the NuSTAR band have motivated us to pursue a systematic search for low cutoff candidates in Swift-BAT detected Seyfert 1 AGN that have been observed with NuSTAR. We use our constraints on the cutoff energy to map out the location of these sources on the compactness - temperature diagram for AGN coronae, and discuss the implications of low cutoff energies for the cooling and thermalization mechanisms in the corona.

The small observed scale of AGN-driven outflows, and inside-out disc quenching

NASA Astrophysics Data System (ADS)

Zubovas, Kastytis; King, Andrew

2016-11-01

Observations of massive outflows with detectable central active galactic nuclei (AGN) typically find them within radii ≲10 kpc. We show that this apparent size restriction is a natural result of AGN driving if this process injects total energy only of the order of the gas binding energy to the outflow, and the AGN varies over time (`flickers') as suggested in recent work. After the end of all AGN activity, the outflow continues to expand to larger radii, powered by the thermal expansion of the remnant-shocked AGN wind. We suggest that on average, outflows should be detected further from the nucleus in more massive galaxies. In massive gas-rich galaxies, these could be several tens of kpc in radius. We also consider the effect that pressure of such outflows has on a galaxy disc. In moderately gas-rich discs, with gas-to-baryon fraction <0.2, the outflow may induce star formation significant enough to be distinguished from quiescent by an apparently different normalization of the Kennicutt-Schmidt law. The star formation enhancement is probably stronger in the outskirts of galaxy discs, so coasting outflows might be detected by their effects upon the disc even after the driving AGN has shut off. We compare our results to the recent inference of inside-out quenching of star formation in galaxy discs.

SDSS IV MaNGA - Properties of AGN Host Galaxies

NASA Astrophysics Data System (ADS)

Sánchez, S. F.; Avila-Reese, V.; Hernandez-Toledo, H.; Cortes-Suárez, E.; Rodríguez-Puebla, A.; Ibarra-Medel, H.; Cano-Díaz, M.; Barrera-Ballesteros, J. K.; Negrete, C. A.; Calette, A. R.; de Lorenzo-Cáceres, A.; Ortega-Minakata, R. A.; Aquino, E.; Valenzuela, O.; Clemente, J. C.; Storchi-Bergmann, T.; Riffel, R.; Schimoia, J.; Riffel, R. A.; Rembold, S. B.; Brownstein, J. R.; Pan, K.; Yates, R.; Mallmann, N.; Bitsakis, T.

2018-04-01

We present the characterization of the main properties of a sample of 98 AGN host galaxies, both type-II and type-I, in comparison with those of ≍2700 non-active galaxies observed by the MaNGA survey. We found that AGN hosts are morphologically early-type or early-spirals. AGN hosts are, on average, more massive, more compact, more centrally peaked and more pressure-supported systems. They are located in the intermediate/transition region between starforming and non-star-forming galaxies (i.e., the so-called green valley). We consider that they are in the process of halting/quenching the star formation. The analysis of the radial distributions of different properties shows that the quenching happens from inside-out involving both a decrease of the effciency of the star formation and a deficit of molecular gas. The data-products of the current analysis are distributed as a Value Added Catalog within the SDSS-DR14.

Merging and Clustering of the Swift BAT AGN Sample

NASA Astrophysics Data System (ADS)

Koss, Michael; Mushotzky, Richard; Veilleux, Sylvain; Winter, Lisa

2010-06-01

We discuss the merger rate, close galaxy environment, and clustering on scales up to an Mpc of the Swift BAT hard X-ray sample of nearby (z<0.05), moderate-luminosity active galactic nuclei (AGNs). We find a higher incidence of galaxies with signs of disruption compared to a matched control sample (18% versus 1%) and of close pairs within 30 kpc (24% versus 1%). We also find a larger fraction with companions compared to normal galaxies and optical emission line selected AGNs at scales up to 250 kpc. We hypothesize that these merging AGNs may not be identified using optical emission line diagnostics because of optical extinction and dilution by star formation. In support of this hypothesis, in merging systems we find a higher hard X-ray to [O III] flux ratio, as well as emission line diagnostics characteristic of composite or star-forming galaxies, and a larger IRAS 60 μm to stellar mass ratio.

Discovering highly obscured AGN with the Swift-BAT 100-month survey

NASA Astrophysics Data System (ADS)

Marchesi, Stefano; Ajello, Marco; Comastri, Andrea; Cusumano, Giancarlo; La Parola, Valentina; Segreto, Alberto

2017-01-01

In this talk, I present a new technique to find highly obscured AGN using the 100-month Swift-BAT survey. I will show the results of the combined Chandra and BAT spectral analysis in the 0.3-150 keV band of seven Seyfert 2 galaxies selected from the 100-month BAT catalog. We selected nearby (z<0.03) sources lacking of a ROSAT counterpart and never previously observed in the 0.3-10 keV energy range. All the objects are significantly obscured, having NH>1E23 cm-2 at a >99% confidence level, and one to three sources are candidate Compton thick Active Galactic Nuclei (CT-AGN), i.e., have NH>1E24 cm-2.Since the selection criteria we adopted have been extremely effective in detecting highly obscured AGN, further observations of these and other Seyfert 2 galaxies selected from the BAT 100-month catalog will allow us to create a statistically significant sample of highly obscured AGN, therefore better understanding the physics of the obscuration processes.

Poynting Robertson Battery and the Chiral Magnetic Fields of AGN Jets

NASA Technical Reports Server (NTRS)

Kazanas, Demosthenes

2010-01-01

We propose that the magnetic fields in the accretion disks of active galactic nuclei (AGNs) are generated by azimuthal electric currents due to the difference between the plasma electron and ion velocities that arises when the electrons are retarded by interactions with the AGN photons (the Poynting Robertson battery). This process provides a unique relation between the polarity of the poloidal B field to the angular velocity Omega of the accretion disk (B is parallel to Omega), a relation absent in the more popular dynamo B-field generation. This then leads to a unique direction for the toroidal B field induced by disk rotation. Observations of the toroidal fields of 29 AGN jets revealed by parsec-scale Faraday rotation measurements show a clear asymmetry that is consistent with this model, with the probability that this asymmetry comes about by chance being approx.0.06 %. This lends support to the hypothesis that the universe is seeded by B fields that are generated in AGNs via this mechanism and subsequently injected into intergalactic space by the jet outflows.

A simple way to improve AGN feedback prescription in SPH simulations

NASA Astrophysics Data System (ADS)

Zubovas, Kastytis; Bourne, Martin A.; Nayakshin, Sergei

2016-03-01

Active galactic nuclei (AGN) feedback is an important ingredient in galaxy evolution, however its treatment in numerical simulations is necessarily approximate, requiring subgrid prescriptions due to the dynamical range involved in the calculations. We present a suite of smoothed particle hydrodynamics simulations designed to showcase the importance of the choice of a particular subgrid prescription for AGN feedback. We concentrate on two approaches to treating wide-angle AGN outflows: thermal feedback, where thermal and kinetic energy is injected into the gas surrounding the supermassive black hole (SMBH) particle, and virtual particle feedback, where energy is carried by tracer particles radially away from the AGN. We show that the latter model produces a far more complex structure around the SMBH, which we argue is a more physically correct outcome. We suggest a simple improvement to the thermal feedback model - injecting the energy into a cone, rather than spherically symmetrically - and show that this markedly improves the agreement between the two prescriptions, without requiring any noticeable increase in the computational cost of the simulation.

The ΓX-L/LEdd relation in BAT AGN Spectroscopic Survey (BASS)

NASA Astrophysics Data System (ADS)

Trakhtenbrot, Benny; Ricci, Claudio; Koss, Michael; Schawinski, Kevin; Mushotzky, Richard; Ueda, Yoshihiro; Veilleux, Sylvain; Lamperti, Isabella; Oh, Kyuseok; Treister, Ezequiel; Stern, Daniel; Harrison, Fiona; Balokovic, Mislav

2018-01-01

We present a study of the relation between accretion rate (in terms of L/LEdd) and shape of the hard X-ray spectral energy distribution (namely the photon index Γx) for a large sample of over 200 hard X-ray-selected, low-redshift active galactic nuclei (AGNs), drawn from the Swift/BAT AGN Spectroscopic Survey (BASS). This includes 30 AGNs for which black hole mass (and therefore L/LEdd) is measured directly through masers, spatially resolved gas or stellar dynamics, or reverberation mapping. The high-quality and broad energy coverage of the data provided through BASS allow us to examine several alternative determinations of both Γx and L/LEdd. We find very weak correlation between Γx and L/LEdd for the BASS sample as a whole, with best-fitting relations that are considerably shallower than those reported in previous studies. Moreover, we find no corresponding correlations among the subsets of AGN with different MBH determination methodology, and in particular those AGN with direct or single-epoch MBH estimates. This latter finding is in contrast to several previous studies which focused on z > 0.5 broad-line AGN. We conclude that this tension can be partially accounted for if one adopts a simplified, power-law X-ray spectral model, combined with L/LEdd estimates that are based on the continuum emission and on single-epoch broad-line spectroscopy in the optical regime. Given these findings, we highlight the limitations of using Γx as a probe of supermassive black hole evolution in deep extragalactic X-ray surveys.

Dust-deficient Palomar-Green Quasars and the Diversity of AGN Intrinsic IR Emission

NASA Astrophysics Data System (ADS)

Lyu, Jianwei; Rieke, G. H.; Shi, Yong

2017-02-01

To elucidate the intrinsic broadband infrared (IR) emission properties of active galactic nuclei (AGNs), we analyze the spectral energy distributions (SEDs) of 87 z ≲ 0.5 Palomar-Green (PG) quasars. While the Elvis AGN template with a moderate far-IR correction can reasonably match the SEDs of the AGN components in ˜60% of the sample (and is superior to alternatives such as that by Assef), it fails on two quasar populations: (1) hot-dust-deficient (HDD) quasars that show very weak emission thoroughly from the near-IR to the far-IR, and (2) warm-dust-deficient (WDD) quasars that have similar hot dust emission as normal quasars but are relatively faint in the mid- and far-IR. After building composite AGN templates for these dust-deficient quasars, we successfully fit the 0.3-500 μm SEDs of the PG sample with the appropriate AGN template, an infrared template of a star-forming galaxy, and a host galaxy stellar template. 20 HDD and 12 WDD quasars are identified from the SED decomposition, including seven ambiguous cases. Compared with normal quasars, the HDD quasars have AGNs with relatively low Eddington ratios and the fraction of WDD quasars increases with AGN luminosity. Moreover, both the HDD and WDD quasar populations show relatively stronger mid-IR silicate emission. Virtually identical SED properties are also found in some quasars from z = 0.5 to 6. We propose a conceptual model to demonstrate that the observed dust deficiency of quasars can result from a change of structures of the circumnuclear tori that can occur at any cosmic epoch.

Reality and myths of AGN feedback

NASA Astrophysics Data System (ADS)

Husemann, Bernd; Harrison, Chris M.

2018-03-01

Feedback from active galactic nuclei (AGNs) remains controversial despite its wide acceptance as necessary to regulate massive galaxy growth. Consequently, we held a workshop in October 2017, at Leiden's Lorentz Center, to distinguish between the reality and myths of feedback.

A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level.

PubMed

Yang, Jihyun; Seo, Min Young; Kim, Ki Tae; Lee, Jun Yong; Kim, Sun-Chul; Kim, Myung-Gyu; Jo, Sang-Kyung; Cho, Won-Yong; Kim, Hyoung-Kyu; Won, Nam Hee; Cha, Ran-Hui; Cho, Eunjung

2014-01-01

Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria and purpura with elevated IgA level rasing a possibility of Henoch-Schölein Purpura (H-S purpura). However, renal biopsy showed "lupus-like feature" glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. Although baseline renal function was maintained without further need for maintenance dialysis following anti-retroviral therapy (ART) and steroid, patient died from uncontrolled gastrointestinal bleeding.

Measuring AGN & Starburst Wind Properties with ALMA

NASA Astrophysics Data System (ADS)

Lacy, Mark; Chatterjee, Suchetana; Nyland, Kristina; Kimball, Amy; Mason, Brian; Rocha, Graca

2018-01-01

The Sunyaev-Zeldovich (SZ) effect is one of the few ways to constrain the energetically-dominant hot component of winds from AGN and starbursts. Studies of stacked data from Planck and ground-based mm/submm single dish telescopes have found significant detections of SZ from quasars, but contamination from other phenomena are hard to rule out given the large beams of single dishes. Direct detection of these winds is just feasible with observations with current facilities (VLA and ALMA), but with ngVLA we should be able to go beyond detections, and start to map the SZ effect around these objects. In this poster I will present predictions for the detectability of SZ decrements from AGN and hyperluminous starbursts using ngVLA parameters.

Warm Absorber Diagnostics of AGN Dynamics

NASA Astrophysics Data System (ADS)

Kallman, Timothy

Warm absorbers and related phenomena are observable manifestations of outflows or winds from active galactic nuclei (AGN) that have great potential value. Understanding AGN outflows is important for explaining the mass budgets of the central accreting black hole, and also for understanding feedback and the apparent co-evolution of black holes and their host galaxies. In the X-ray band warm absorbers are observed as photoelectric absorption and resonance line scattering features in the 0.5-10 keV energy band; the UV band also shows resonance line absorption. Warm absorbers are common in low luminosity AGN and they have been extensively studied observationally. They may play an important role in AGN feedback, regulating the net accretion onto the black hole and providing mechanical energy to the surroundings. However, fundamental properties of the warm absorbers are not known: What is the mechanism which drives the outflow?; what is the gas density in the flow and the geometrical distribution of the outflow?; what is the explanation for the apparent relation between warm absorbers and the surprising quasi-relativistic 'ultrafast outflows' (UFOs)? We propose a focused set of model calculations that are aimed at synthesizing observable properties of warm absorber flows and associated quantities. These will be used to explore various scenarios for warm absorber dynamics in order to answer the questions in the previous paragraph. The guiding principle will be to examine as wide a range as possible of warm absorber driving mechanisms, geometry and other properties, but with as careful consideration as possible to physical consistency. We will build on our previous work, which was a systematic campaign for testing important class of scenarios for driving the outflows. We have developed a set of tools that are unique and well suited for dynamical calculations including radiation in this context. We also have state-of-the-art tools for generating synthetic spectra, which are

Near-infrared Variability of Obscured and Unobscured X-Ray-selected AGNs in the COSMOS Field

NASA Astrophysics Data System (ADS)

Sánchez, P.; Lira, P.; Cartier, R.; Pérez, V.; Miranda, N.; Yovaniniz, C.; Arévalo, P.; Milvang-Jensen, B.; Fynbo, J.; Dunlop, J.; Coppi, P.; Marchesi, S.

2017-11-01

We present our statistical study of near-infrared (NIR) variability of X-ray-selected active galactic nuclei (AGNs) in the COSMOS field, using UltraVISTA data. This is the largest sample of AGN light curves in YJHKs bands, making it possible to have a global description of the nature of AGNs for a large range of redshifts and for different levels of obscuration. To characterize the variability properties of the sources, we computed the structure function. Our results show that there is an anticorrelation between the structure function A parameter (variability amplitude) and the wavelength of emission and a weak anticorrelation between A and the bolometric luminosity. We find that broad-line (BL) AGNs have a considerably larger fraction of variable sources than narrow-line (NL) AGNs and that they have different distributions of the A parameter. We find evidence that suggests that most of the low-luminosity variable NL sources correspond to BL AGNs, where the host galaxy could be damping the variability signal. For high-luminosity variable NL sources, we propose that they can be examples of “true type II” AGNs or BL AGNs with limited spectral coverage, which results in missing the BL emission. We also find that the fraction of variable sources classified as unobscured in the X-ray is smaller than the fraction of variable sources unobscured in the optical range. We present evidence that this is related to the differences in the origin of the obscuration in the optical and X-ray regimes.

Investigating Possible Outliers in the Fermi Blazar AGN Sample

NASA Astrophysics Data System (ADS)

Shrader, Chris

2018-01-01

The Fermi Gamma-Ray Space Telescope (Fermi) has cataloged over 3000 gamma-ray (>100 MeV) point sources of which more than 1100 are likely AGN. These AGN are predominantly among the radio-loud “blazar” subclass. Recently however, a significant sample of bright (F_15GHz >1.5 Jy), radio selected AGN was found to overlap with Fermi at only the ~80% level (Lister et. al., 2015). This could be a result of some selection bias or it could be due to deficient Doppler boosting among that ~20%. Additionally, a recent survey of high-latitude gamma-ray sources by Schinzel et al. (2017) reveals a sample of ~100 objects which are not detected in the 4-10 GHz radio band to a limiting flux of about 2mJy. This apparent lack of radio flux is puzzling, and may indicate either an extreme Compton-dominated sample, or copious gamma-ray emission from a heretofore unknown population such as a subclass of radio-quiet AGN. Speculatively, these radio-loud/gamma-quiet and gamma-loud/radio quiet samples could be odd cases of the blazar phenomena which reside outside of the well-known blazar sequence. To explore this problem further we have undertaken a study to construct or constrain individual source SEDs as a first step towards their classification. In this contribution we present results from our search for emission in the Swift-BAT 15-100-keV hard X-ray band for each of these samples.

The remarkable AGN jets

NASA Astrophysics Data System (ADS)

Komissarov, Serguei

The jets from active galactic nuclei exhibit stability which seems to be far superior compared to that of terrestrial and laboratory jets. They manage to propagate over distances up to a billion of initial jet radii. Yet this may not be an indication of some exotic physics but mainly a reflection of the specific environment these jets propagate through. The key property of this environment is a rapid decline of density and pressure along the jet, which promotes its rapid expansion. Such an expansion can suppress global instabilities, which require communication across the jet, and hence ensure its survival over huge distances. At kpc scales, some AGN jets do show signs of strong instabilities and even turn into plumes. This could be a result of the flattening of the external pressure distribution in their host galaxies or inside the radio lobes. In this regard, we discuss the possible connection between the stability issue and the Fanaroff-Riley classification of extragalactic radio sources. The observations of AGN jets on sub-kpc scale do not seem to support their supposed lack of causal connectivity. When interpreted using simple kinematic models, they reveal a rather perplexing picture with more questions than answers on the jets dynamics.

ON THE IMPORTANCE OF VERY LIGHT INTERNALLY SUBSONIC AGN JETS IN RADIO-MODE AGN FEEDBACK

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guo, Fulai, E-mail: fulai@shao.ac.cn

Radio-mode active galactic nucleus (AGN) feedback plays a key role in the evolution of galaxy groups and clusters. Its physical origin lies in the kiloparsec-scale interaction of AGN jets with the intracluster medium. Large-scale jet simulations often initiate light internally supersonic jets with density contrast 0.01 < η < 1. Here we argue for the first time for the importance of very light ( η < 0.01) internally subsonic jets. We investigated the shapes of young X-ray cavities produced in a suite of hydrodynamic simulations, and found that bottom-wide cavities are always produced by internally subsonic jets, while internally supersonicmore » jets inflate cylindrical, center-wide, or top-wide cavities. We found examples of real cavities with shapes analogous to those inflated in our simulations by internally subsonic and internally supersonic jets, suggesting a dichotomy of AGN jets according to their internal Mach numbers. We further studied the long-term cavity evolution, and found that old cavities resulted from light jets spread along the jet direction, while those produced by very light jets are significantly elongated along the perpendicular direction. The northwestern ghost cavity in Perseus is pancake shaped, providing tentative evidence for the existence of very light jets. Our simulations show that very light internally subsonic jets decelerate faster and rise much slower in the intracluster medium than light internally supersonic jets, possibly depositing a larger fraction of jet energy to cluster cores and alleviating the problem of low coupling efficiencies found previously. The internal Mach number points to the jet’s energy content, and internally subsonic jets are energetically dominated by non-kinetic energy, such as thermal energy, cosmic rays, or magnetic fields.« less

Searching for Dual AGNs in Galaxy Mergers: Understanding Double-Peaked [O III] and Ultra Hard X-rays as Selection Method

NASA Astrophysics Data System (ADS)

McGurk, Rosalie C.; Max, Claire E.; Medling, Anne; Shields, Gregory A.

2015-01-01

When galaxies merge, gas accretes onto both central supermassive black holes. Thus, one expects to see close pairs of active galactic nuclei (AGNs), or dual AGNs, in a fraction of galaxy mergers. However, finding them remains a challenge. The presence of double-peaked [O III] or of ultra hard X-rays have been proposed as techniques to select dual AGNs efficiently. We studied a sample of double-peaked narrow [O III] emitting AGNs from SDSS DR7. By obtaining new and archival high spatial resolution images taken with the Keck 2 Laser Guide Star Adaptive Optics system and the near-infrared (IR) camera NIRC2, we showed that 30% of double-peaked [O III] emission line SDSS AGNs have two spatial components within a 3' radius. However, spatially resolved spectroscopy or X-ray observations are needed to confirm these galaxy pairs as systems containing two AGNs. We followed up these spatially-double candidate dual AGNs with integral field spectroscopy from Keck OSIRIS and Gemini GMOS and with long-slit spectroscopy from Keck NIRSPEC and Shane Kast Double Spectrograph. We find double-peaked emitters are caused sometimes by dual AGN and sometimes by outflows or narrow line kinematics. We also performed Chandra X-ray ACIS-S observations on 12 double-peaked candidate dual AGNs. Using our observations and 8 archival observations, we compare the distribution of X-ray photons to our spatially double near-IR images, measure X-ray luminosities and hardness ratios, and estimate column densities. By assessing what fraction of double-peaked emission line SDSS AGNs are true dual AGNs, we can better determine whether double-peaked [O III] is an efficient dual AGN indicator and constrain the statistics of dual AGNs. A second technique to find dual AGN is the detection of ultra hard X-rays by the Swift Burst Alert Telescope. We use CARMA observations to measure and map the CO(1-0) present in nearby ultra-hard X-ray Active Galactic Nuclei (AGNs) merging with either a quiescent companion

Obscured and powerful AGN and starburst activities at z ~ 3.5

NASA Astrophysics Data System (ADS)

Polletta, M.; Omont, A.; Berta, S.; Bergeron, J.; Stalin, C. S.; Petitjean, P.; Giorgetti, M.; Trinchieri, G.; Srianand, R.; McCracken, H. J.; Pei, Y.; Dannerbauer, H.

2008-12-01

Aims: Short phases of coeval powerful starburst and AGN activity during the lifetimes of the most massive galaxies are predicted by various models of galaxy formation and evolution. In spite of their recurrence and high luminosity, such events are rarely observed. Finding such systems, understanding their nature, and constraining their number density can provide key constraints to galaxy evolutionary models and insights into the interplay between starburst and AGN activities. Methods: We report the discovery of two sources at z=3.867 and z=3.427 that exhibit both powerful starburst and AGN activities. They benefit from multi-wavelength data from radio to X rays from the CFHTLS-D1/SWIRE/XMDS surveys. Follow-up optical and near-infrared spectroscopy, and millimeter IRAM/MAMBO observations are also available. We performed a multi-wavelength analysis of their spectral energy distributions with the aim of understanding the origin of their emission and constraining their luminosities. A comparison with other composite systems at similar redshifts from the literature is also presented. Results: The AGN and starburst bolometric luminosities are 1013 L⊙. The AGN emission dominates at X ray, optical, mid-infrared wavelengths, and probably also in the radio. The starburst emission dominates in the far-infrared. The estimated star formation rates range from 500 to 3000 M⊙/yr. The AGN near-infrared and X ray emissions are heavily obscured in both sources with an estimated dust extinction {A_V} ≥ 4, and Compton-thick gas column densities. The two sources are the most obscured and most luminous AGNs detected at millimeter wavelengths currently known. Conclusions: The sources presented in this work are heavily obscured QSOs, but their properties are not fully explained by the standard AGN unification model. In one source, the ultraviolet and optical spectra suggest the presence of outflowing gas and shocks, and both sources show emission from hot dust, most likely in the

Accretion disk modeling of AGN continuum using non-LTE stellar atmospheres. [active galactic nuclei (AGN)

NASA Technical Reports Server (NTRS)

Sun, Wei-Hsin; Malkan, Matthew A.

1988-01-01

Active galactic nuclei (AGN) accretion disk spectra were calculated using non-LTE stellar atmosphere models for Kerr and Schwarzschild geometries. It is found that the Lyman limit absorption edge, probably the most conclusive observational evidence for the accretion disk, would be drastically distorted and displaced by the relativistic effects from the large gravitational field of the central black hole and strong Doppler motion of emitting material on the disk surface. These effects are especially pronounced in the Kerr geometry. The strength of the Lyman limit absorption is very sensitive to the surface gravity in the stellar atmosphere models used. For models at the same temperature but different surface gravities, the strength of the Lyman edge exhibits an almost exponential decrease as the surface gravity approach the Eddington limit, which should approximate the thin disk atmosphere. The relativistic effects as well as the vanishing of the Lyman edge at the Eddington gravity may be the reasons that not many Lyman edges in the rest frames of AGNs and quasars are found.

[Mechanisms of immune deposit formation in glomerulonephritis].

PubMed

Bussolati, B; Camussi, G

1996-03-01

Recent experimental studies allowed the identification of several mechanisms of immune deposit formation, which are able to reproduce the morphological and clinical pattern of human glomerulonephritis. Moreover, it was shown that most of the lesions considered, in the past, as due to circulating immune complexes (IC), are instead caused by the "in situ" formation of IC. As a result of these studies, the following schematic classification was proposed: 1) immune deposits formed by glomerular localization of IC primarily formed in the circulation; 2) immune deposits formed "in situ" by reaction of circulating antibodies with fixed structural antigens; 3) immune deposits formed "in situ" by antibodies reactive with movable structural antigens; 4) immune deposits formed "in situ" by antibodies reactive with sequestered antigens leaking out of tissues; 5) IC formed "in situ" by antibodies reactive with exogenous or non-glomerular endogenous antigens planted in the glomeruli; 6) ANCA-associated glomerular disease.

Reversing cooling flows with AGN jets: shock waves, rarefaction waves and trailing outflows

NASA Astrophysics Data System (ADS)

Guo, Fulai; Duan, Xiaodong; Yuan, Ye-Fei

2018-01-01

The cooling flow problem is one of the central problems in galaxy clusters, and active galactic nucleus (AGN) feedback is considered to play a key role in offsetting cooling. However, how AGN jets heat and suppress cooling flows remains highly debated. Using an idealized simulation of a cool-core cluster, we study the development of central cooling catastrophe and how a subsequent powerful AGN jet event averts cooling flows, with a focus on complex gasdynamical processes involved. We find that the jet drives a bow shock, which reverses cooling inflows and overheats inner cool-core regions. The shocked gas moves outward in a rarefaction wave, which rarefies the dense core and adiabatically transports a significant fraction of heated energy to outer regions. As the rarefaction wave propagates away, inflows resume in the cluster core, but a trailing outflow is uplifted by the AGN bubble, preventing gas accumulation and catastrophic cooling in central regions. Inflows and trailing outflows constitute meridional circulations in the cluster core. At later times, trailing outflows fall back to the cluster centre, triggering central cooling catastrophe and potentially a new generation of AGN feedback. We thus envisage a picture of cool cluster cores going through cycles of cooling-induced contraction and AGN-induced expansion. This picture naturally predicts an anti-correlation between the gas fraction (or X-ray luminosity) of cool cores and the central gas entropy, which may be tested by X-ray observations.

High-energy neutrino fluxes from AGN populations inferred from X-ray surveys

NASA Astrophysics Data System (ADS)

Jacobsen, Idunn B.; Wu, Kinwah; On, Alvina Y. L.; Saxton, Curtis J.

2015-08-01

High-energy neutrinos and photons are complementary messengers, probing violent astrophysical processes and structural evolution of the Universe. X-ray and neutrino observations jointly constrain conditions in active galactic nuclei (AGN) jets: their baryonic and leptonic contents, and particle production efficiency. Testing two standard neutrino production models for local source Cen A (Koers & Tinyakov and Becker & Biermann), we calculate the high-energy neutrino spectra of single AGN sources and derive the flux of high-energy neutrinos expected for the current epoch. Assuming that accretion determines both X-rays and particle creation, our parametric scaling relations predict neutrino yield in various AGN classes. We derive redshift-dependent number densities of each class, from Chandra and Swift/BAT X-ray luminosity functions (Silverman et al. and Ajello et al.). We integrate the neutrino spectrum expected from the cumulative history of AGN (correcting for cosmological and source effects, e.g. jet orientation and beaming). Both emission scenarios yield neutrino fluxes well above limits set by IceCube (by ˜4-106 × at 1 PeV, depending on the assumed jet models for neutrino production). This implies that: (i) Cen A might not be a typical neutrino source as commonly assumed; (ii) both neutrino production models overestimate the efficiency; (iii) neutrino luminosity scales with accretion power differently among AGN classes and hence does not follow X-ray luminosity universally; (iv) some AGN are neutrino-quiet (e.g. below a power threshold for neutrino production); (v) neutrino and X-ray emission have different duty cycles (e.g. jets alternate between baryonic and leptonic flows); or (vi) some combination of the above.

2MASS J00423991+3017515: An Interacting Oddball or a Recoiling AGN?

NASA Astrophysics Data System (ADS)

Hogg, J. Drew; Blecha, Laura; Reynolds, Christopher S.

2017-06-01

We present deep, multiband Hubble imaging and two epochs of optical spectroscopic monitoring of a peculiar nearby (z=0.14) AGN, 2MASS J00423991+3017515. The host galaxy containing the AGN is morphologically disturbed and interacting with an unmerged companion galaxy, suggesting it has had a rich merger history. The AGN itself is spatially displaced from the apparent center of its host galaxy and the symmetric broad Hα and Hβ lines are consistently blueshifted from the narrow line emission and host galaxy absorption by Δv = 1530 km/s. The investigation is ongoing, but we put forward two hypotheses to explain the odd features of this system. First, the abnormalities could be due to separate, independent causes. Projection effects from the interaction of the two galaxies could give the appearance of a spatial offset, while complex wind dynamics from the AGN accretion disk could give rise to the kinematic shift in the broad line emission. Second, this could be a recoiling AGN. This system fits the template of an accreting supermassive black hole (SMBH) that has recently received a “kick” from the asymmetric emission of gravitational waves (GWs) following the merger of two progenitor SMBHs. SMBH mergers are a likely end-product of hierarchical structure formation and are the supermassive cousins of the stellar-mass BH mergers observed with LIGO in the GW150914 and GW151226 events. However, a SMBH merger has yet to be unambigously detected. If confirmed as a recoiling AGN, 2MASS J00423991+3017515 will provide the first evidence of this growth pathway acting in the SMBH regime.

The Cosmological Impact of AGN Outflows: Measuring Absolute Abundances and Kinetic Luminosities

NASA Astrophysics Data System (ADS)

Arav, Nahum

2009-07-01

AGN outflows are increasingly invoked as a major contributor to the formation and evolution of supermassive black holes, their host galaxies, the surrounding IGM, and cluster cooling flows. Our HST/COS proposal will determine reliable absolute chemical abundances in six AGN outflows, which influences several of the processes mentioned above. To date there is only one such determination, done by our team on Mrk 279 using 16 HST/STIS orbits and 100 ksec of FUSE time. The advent of COS and its high sensitivity allows us to choose among fainter objects at redshifts high enough to preclude the need for FUSE. This will allow us to determine the absolute abundances for six AGN {all fainter than Mrk 279} using only 40 HST COS orbits. This will put abundances studies in AGN on a firm footing, an elusive goal for the past four decades. In addition, prior FUSE observations of four of these targets indicate that it is probable that the COS observations will detect troughs from excited levels of C III. These will allow us to measure the distances of the outflows and thereby determine their kinetic luminosity, a major goal in AGN feedback research. We will use our state of the art column density extraction methods and velocity-dependent photoionization models to determine the abundances and kinetic luminosity. Previous AGN outflow projects suffered from the constraints of deciding what science we could do using ONE of the handful of bright targets that were observable. With COS we can choose the best sample for our experiment. As an added bonus, most of the spectral range of our targets has not been observed previously, greatly increasing the discovery phase space.

Anomalous H-beta Variability in the 2014 NGC 5548 AGN-STORM Monitoring Campaign

NASA Astrophysics Data System (ADS)

Pei, Liuyi; AGN STORM Collaboration

2016-06-01

Reverberation mapping programs generally find that the continuum and H-beta flux variations in AGNs are well correlated. In the 2014 AGN STORM monitoring program for NGC 5548, we observed a distinct decorrelation of the emission-line light curves from the AGN continuum light curve during the second half of the six-month campaign. This effect was first detected for the C IV, Ly a, HeII 1640 and SiIV/OIV] 1400 lines in Hubble Space Telescope data, then observed for the H-beta line in ground-based data taken during the same monitoring period. We present measurements of the H-beta lags, equivalent width variations, and line responsivity changes during our campaign. We show that the AGN demonstrated unusual behavior in that the broad H-beta responsivity to flux variations decreased significantly during the second half of the campaign. The discovery of this decorrelation phenomenon was made possible by the high cadence and long duration of our monitoring campaign. More multi-wavelength observing campaigns with high sampling cadence, high signal-to-noise ratio, and long temporal baseline are needed for other AGNs in order to determine the prevalence of this phenomenon and to understand its physical origin.

The role of Th1 and Th17 cells in glomerulonephritis.

PubMed

Azadegan-Dehkordi, Fatemeh; Bagheri, Nader; Shirzad, Hedayatollah; Rafieian-Kopaei, Mahmoud

2015-04-01

T helper (Th) cells as an important part of the immune is responsible for elimination of invading pathogens. But, if Th cell responses are not regulated effectively, the autoimmune diseases might develop. The Th17 subset usually produces interleukin-17A which in experimental models of organ-specific autoimmune inflammation is very important. Directory of open access journals (DOAJ), Google Scholar, Embase, Scopus, PubMed and Web of Science have been searched. Fifty-six articles were found and searched. In the present review article, we tried to summarize the recently published data about characteristics and role of Th1 and Th17 cells and discuss in detail, the potential role of these T helpers immune responses in renal inflammation and renal injury, focusing on glomerulonephritis. Published papers in animal and human studies indicated that autoimmune diseases such as rheumatoid arthritis and multiple sclerosis, classically believed to be Th1-mediated, are mainly derived from a Th17 immune response. Identification of the Th17 subgroup has explained seemingly paradoxical observations and improved our understanding of immune-mediated inflammatory responses. Secretion of IL-17A, as well as IL-17F, IL-21, IL-22, suggests that Th17 subset may play a crucial role as a pleiotropic pro-inflammatory Th subset. There is experimental evidence to support the notion that Th1 and Th17 cells contribute to kidney injury in renal inflammatory diseases like glomerulonephritis.

Ionized Absorbers in AGN

NASA Technical Reports Server (NTRS)

Mathur, S.

1999-01-01

As a part of this program, we observed three AGN:PKS2251 + 113, PG0043 = 039 and PLH909. Two objects show signatures of absorbtion in their UV spectra. Based on our earlier modeling of X-ray warm absorbents, we expected to observe X-ray observation in these objects. The third, PLH909, is known to have soft excess in EINSTEIN data. Attachment: "Exploratory ASCA observation of broad absorption line quasi-stellar objects".

Highly variable AGN from the XMM-Newton slew survey

NASA Astrophysics Data System (ADS)

Strotjohann, N. L.; Saxton, R. D.; Starling, R. L. C.; Esquej, P.; Read, A. M.; Evans, P. A.; Miniutti, G.

2016-07-01

Aims: We investigate the properties of a variability-selected complete sample of active galactic nuclei (AGN) in order to identify the mechanisms which cause large amplitude X-ray variability on timescales of years. Methods: A complete sample of 24 sources was constructed, from AGN which changed their soft X-ray luminosity by more than one order of magnitude over 5-20 years between ROSAT observations and the XMM-Newton slew survey. Follow-up observations were obtained with the Swift satellite. We analysed the spectra of these AGN at the Swift and XMM observation epochs, where six sources had continued to display extreme variability. Multiwavelength data are used to calculate black hole masses and the relative X-ray brightness αOX. Results: After removal of two probable spurious sources, we find that the sample has global properties which differ little from a non-varying control sample drawn from the wider XMM-slew/ROSAT/Veron sample of all secure AGN detections. A wide range of AGN types are represented in the varying sample. The black hole mass distributions for the varying and non-varying sample are not significantly different. This suggests that long timescale variability is not strongly affected by black hole mass. There is marginal evidence that the variable sources have a lower redshift (2σ) and X-ray luminosity (1.7σ). Apart from two radio-loud sources, the sample sources have normal optical-X-ray ratios (αOX) when at their peak but are X-ray weak during their lowest flux measurements. Conclusions: Drawing on our results and other studies, we are able to identify a variety of variability mechanisms at play: tidal disruption events, jet activity, changes in absorption, thermal emission from the inner accretion disc, and variable accretion disc reflection. Little evidence for strong absorption is seen in the majority of the sample and single-component absorption can be excluded as the mechanism for most sources.

The COS-AGN survey: Revealing the nature of circum-galactic gas around hosts of active galactic nuclei

NASA Astrophysics Data System (ADS)

Berg, Trystyn A. M.; Ellison, Sara L.; Tumlinson, Jason; Oppenheimer, Benjamin D.; Horton, Ryan; Bordoloi, Rongmon; Schaye, Joop

2018-04-01

Active galactic nuclei (AGN) are thought to play a critical role in shaping galaxies, but their effect on the circumgalactic medium (CGM) is not well studied. We present results from the COS-AGN survey: 19 quasar sightlines that probe the CGM of 20 optically-selected AGN host galaxies with impact parameters 80 <ρimp<300 kpc. Absorption lines from a variety of species are measured and compared to a stellar mass and impact parameter matched sample of sightlines through non-AGN galaxies. Amongst the observed species in the COS-AGN sample (Lyα, Cii , Siii , Siiii , Civ , Siiv , Nv ), only Lyα shows a high covering fraction (94^{+6}_{-23}% for rest-frame equivalent widths EW≥124 mÅ) whilst many of the metal ions are not detected in individual sightlines. A sightline-by-sightline comparison between COS-AGN and the control sample yields no significant difference in EW distribution. However, stacked spectra of the COS-AGN and control samples show significant (>3σ) enhancements in the EW of both Siiii And Lyα at impact parameters >164 kpc by a factor of +0.45 ± 0.05 dex and >+0.75 dex respectively. The lack of detections of both high-ionization species near the AGN and strong kinematic offsets between the absorption systemic galaxy redshifts indicates that neither the AGN's ionization nor its outflows are the origin of these differences. Instead, we suggest the observed differences could result from either AGN hosts residing in haloes with intrinsically distinct gas properties, or that their CGM has been affected by a previous event, such as a starburst, which may also have fuelled the nuclear activity.

AGN-enhanced outflows of low-ionization gas in star-forming galaxies at 1.7 < z < 4.6*

NASA Astrophysics Data System (ADS)

Talia, M.; Brusa, M.; Cimatti, A.; Lemaux, B. C.; Amorin, R.; Bardelli, S.; Cassarà, L. P.; Cucciati, O.; Garilli, B.; Grazian, A.; Guaita, L.; Hathi, N. P.; Koekemoer, A.; Le Fèvre, O.; Maccagni, D.; Nakajima, K.; Pentericci, L.; Pforr, J.; Schaerer, D.; Vanzella, E.; Vergani, D.; Zamorani, G.; Zucca, E.

2017-11-01

Fast and energetic winds are invoked by galaxy formation models as essential processes in the evolution of galaxies. These outflows can be powered either by star formation (SF) and/or active galactic nucleus (AGN) activity, but the relative dominance of the two mechanisms is still under debate. We use spectroscopic stacking analysis to study the properties of the low-ionization phase of the outflow in a sample of 1330 star-forming galaxies (SFGs) and 79 X-ray-detected (1042 < LX < 1045 erg s-1) Type 2 AGN at 1.7 < z < 4.6 selected from a compilation of deep optical spectroscopic surveys, mostly zCOSMOS-Deep and VIMOS Ultra Deep Survey (VUDS). We measure mean velocity offsets of ˜- 150 km s-1 in the SFGs, while in the AGN sample the velocity is much higher (˜- 950 km s-1), suggesting that the AGN is boosting the outflow up to velocities that could not be reached only with the SF contribution. The sample of X-ray AGN has on average a lower SF rate than non-AGN SFGs of similar mass: this, combined with the enhanced outflow velocity in AGN hosts, is consistent with AGN feedback in action. We further divide our sample of AGN into two X-ray luminosity bins: we measure the same velocity offsets in both stacked spectra, at odds with results reported for the highly ionized phase in local AGN, suggesting that the two phases of the outflow may be mixed only up to relatively low velocities, while the highest velocities can be reached only by the highly ionized phase.

Impact of an AGN featureless continuum on estimation of stellar population properties

NASA Astrophysics Data System (ADS)

Cardoso, Leandro S. M.; Gomes, Jean Michel; Papaderos, Polychronis

2017-08-01

The effect of the featureless power-law (PL) continuum of an active galactic nucleus (AGN) on the estimation of physical properties of galaxies with optical population spectral synthesis (PSS) remains largely unknown. With the goal of a quantitative examination of this issue, we fit synthetic galaxy spectra representing a wide range of galaxy star formation histories (SFHs) and including distinct PL contributions of the form Fν ∝ ν- α with the PSS code Starlight to study to which extent various inferred quantities (e.g. stellar mass, mean age, and mean metallicity) match the input. The synthetic spectral energy distributions (SEDs) computed with our evolutionary spectral synthesis code include an AGN PL component with 0.5 ≤ α ≤ 2 and a fractional contribution 0.2 ≤ xAGN ≤ 0.8 to the monochromatic flux at 4020 Å. At the empirical AGN detection threshold xAGN ≃ 0.26 that we previously inferred in a pilot study on this subject, our results show that the neglect of a PL component in spectral fitting can lead to an overestimation by 2 dex in stellar mass and by up to 1 and 4 dex in the light- and mass-weighted mean stellar age, respectively, whereas the light- and mass-weighted mean stellar metallicity are underestimated by up to 0.3 and 0.6 dex, respectively. These biases, which become more severe with increasing xAGN, are essentially independent of the adopted SFH and show a complex behaviour with evolutionary time and α. Other fitting set-ups including either a single PL or multiple PLs in the base reveal, on average, much lower unsystematic uncertainties of the order of those typically found when fitting purely stellar SEDs with stellar templates, however, reaching locally up to 1, 3 and 0.4 dex in mass, age and metallicity, respectively. Our results underscore the importance of an accurate modelling of the AGN spectral contribution in PSS fits as a minimum requirement for the recovery of the physical and evolutionary properties of stellar

The 60 Month All-Sky Burst Alert Telescope Survey of Active Galactic Nucleus and the Anisotropy of Nearby AGNs

NASA Technical Reports Server (NTRS)

Ajello, M.; Alexander, D. M.; Greiner, J.; Madejeski, G. M.; Gehrels, N.; Burlon, D.

2014-01-01

Surveys above 10 keV represent one of the best resources to provide an unbiased census of the population of active galactic nuclei (AGNs). We present the results of 60 months of observation of the hard X-ray sky with Swift/Burst Alert Telescope (BAT). In this time frame, BAT-detected (in the 15-55 keV band) 720 sources in an all-sky survey of which 428 are associated with AGNs, most of which are nearby. Our sample has negligible incompleteness and statistics a factor of approx. 2 larger over similarly complete sets of AGNs. Our sample contains (at least) 15 bona fide Compton-thick AGNs and 3 likely candidates. Compton-thick AGNs represent approx. 5% of AGN samples detected above 15 keV. We use the BAT data set to refine the determination of the log N-log S of AGNs which is extremely important, now that NuSTAR prepares for launch, toward assessing the AGN contribution to the cosmic X-ray background. We show that the log N-log S of AGNs selected above 10 keV is now established to approx. 10% precision. We derive the luminosity function of Compton-thick AGNs and measure a space density of 7.9(+4.1/-2.9)× 10(exp -5)/cubic Mpc for objects with a de-absorbed luminosity larger than 2 × 10(exp 42) erg / s. As the BAT AGNs are all mostly local, they allow us to investigate the spatial distribution of AGNs in the nearby universe regardless of absorption. We find concentrations of AGNs that coincide spatially with the largest congregations of matter in the local (much < 85 Mpc) universe. There is some evidence that the fraction of Seyfert 2 objects is larger than average in the direction of these dense regions..

A census of radio-selected AGNs on the COSMOS field and of their FIR properties

NASA Astrophysics Data System (ADS)

Magliocchetti, M.; Popesso, P.; Brusa, M.; Salvato, M.

2018-01-01

We use the new catalogue by Laigle et al. to provide a full census of VLA-COSMOS radio sources. We identify 90 per cent of such sources and sub-divide them into active galactic nuclei (AGNs) and star-forming galaxies on the basis of their radio luminosity. The AGN sample is complete with respect to radio selection at all z ≲ 3.5. Out of 704 AGNs, 272 have a counterpart in the Herschel maps. By exploiting the better statistics of the new sample, we confirm the results of Magliocchetti et al.: the probability for a radio-selected AGN to be detected at far-infrared (FIR) wavelengths is both a function of radio luminosity and redshift, whereby powerful sources are more likely FIR emitters at earlier epochs. Such an emission is due to star-forming processes within the host galaxy. FIR emitters and non-FIR emitters only differentiate in the z ≲ 1 universe. At higher redshifts, they are indistinguishable from each other, as there is no difference between FIR-emitting AGNs and star-forming galaxies. Lastly, we focus on radio AGNs which show AGN emission at other wavelengths. We find that mid-infrared (MIR) emission is mainly associated with ongoing star formation and with sources which are smaller, younger and more radio luminous than the average parent population. X-ray emitters instead preferentially appear in more massive and older galaxies. We can therefore envisage an evolutionary track whereby the first phase of a radio-active AGN and of its host galaxy is associated with MIR emission, while at later stages the source becomes only active at radio wavelengths and possibly also in the X-ray.

Searching for faint AGN in the CDFS: an X-ray (Chandra) vs optical variability (HST) comparison.

NASA Astrophysics Data System (ADS)

Georgantopoulos, I.; Pouliasis, E.; Bonanos, A.; Sokolovsky, K.; Yang, M.; Hatzidimitriou, D.; Bellas, I.; Gavras, P.; Spetsieri, Z.

2017-10-01

X-ray surveys are believed to be the most efficient way to detect AGN. Recently though, optical variability studies are claimed to probe even fainter AGN. We are presenting results from an HST study aimed to identify Active Galactic Nuclei (AGN) through optical variability selection in the CDFS.. This work is part of the 'Hubble Catalogue of Variables'project of ESA that aims to identify variable sources in the Hubble Source Catalogue.' In particular, we used Hubble Space Telescope (HST) z-band images taken over 5 epochs and performed aperture photometry to derive the lightcurves of the sources. Two statistical methods (standard deviation & interquartile range) resulting in a final sample of 175 variable AGN candidates, having removed the artifacts by visual inspection and known stars and supernovae. The fact that the majority of the sources are extended and variable indicates AGN activity. We compare the efficiency of the method by comparing with the 7Ms Chandra detections. Our work shows that the optical variability probes AGN at comparable redshifts but at deeper optical magnitudes. Our candidate AGN (non detected in X-rays) have luminosities of L_x<6×10^{40} erg/sec at z˜0.7 suggesting that these are associated with low luminosity Seyferts and LINERS.

Correlating The Star Formation Histories Of MaNGA Galaxies With Their Past AGN Activity

NASA Astrophysics Data System (ADS)

Gonzalez Ortiz, Andrea

2017-01-01

We investigate active galactic nuclei (AGN) as a primary mechanism affecting star formation in MaNGA galaxies. Using the Pipe3D code, we modeled the stellar population from MaNGA spectra and derived the star formation histories of 53 AGN host galaxies. We seek to compare the star formation histories of the host galaxies of AGN with the ages of their radio lobes to better understand the role of AGN feedback in the star formation histories of MaNGA galaxies. MaNGA (Mapping Nearby Galaxies at APO) is one of the three core programs in the fourth generation Sloan Digital Sky Survey(SDSS). MaNGA will investigate the internal kinematics of nearly 10,000 local galaxies through dithered observations using fiber integral field units (IFUs) that vary in diameter from 12" (19 fibers) to 32" (127 fibers). In this poster, we present initial results on the star formation histories of MaNGA AGN host galaxies. This work was supported by the SDSS Research Experience for Undergraduates program, which is funded by a grant from Sloan Foundation to the Astrophysical Research Consortium.

A statistical study of H i gas in nearby narrow-line AGN-hosting galaxies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhu, Yi-Nan; Wu, Hong, E-mail: zyn@bao.ac.cn, E-mail: hwu@bao.ac.cn

As a quenching mechanism, active galactic nucleus (AGN) feedback could suppress on going star formation in host galaxies. On the basis of a sample of galaxies selected from the Arecibo Legacy Fast ALFA (ALFALFA) H i survey, the dependence of the H i mass (M{sub H} {sub i}), stellar mass (M{sub *}), and H i-to-stellar mass ratio (M{sub H} {sub i}/M{sub *}) on various tracers of AGN activity are presented and analyzed in this paper. Almost all the AGN hostings in this sample are gas-rich galaxies, and there is not any evidence to indicate that the AGN activity could increasemore » or decrease either M{sub H} {sub i} or M{sub H} {sub i}/M{sub *}. The position of the cold neutral gas cannot be fixed accurately based only on available H i data, due to the large beam size of ALFALFA survey. In addition, even though AGN hostings are more easily detected by an H i survey compared with absorption line galaxies, these two types of galaxies show similar star formation history. If an AGN hosting would ultimately evolve into an old red galaxy with low cold gas, then when and how the gas has been exhausted must be solved by future hypotheses and observations.« less

Mapping Sub-pc Structure in AGNs with Water Vapor Megamasers

NASA Astrophysics Data System (ADS)

Braatz, James; Reid, Mark; Condon, James; Lo, K. Y.; Henkel, Christian; Kuo, Cheng-Yu; Impellizzeri, Violette; Gao, Feng; Zhao, Wei; Greene, Jenny; Constantin, Anca

2012-12-01

VLBI observations of water vapor megamasers provide the only direct means of mapping gas in AGNs on sub-parsec scales. Altogether, megamasers have been detected in about 150 galaxies, most of them nearby (z < 0.05), type 2 AGNs. Twenty one of these systems have now been mapped with VLBI. In about 25% of all maser-detected galaxies, the single-dish spectrum of the emission reveals a triple-peaked profile characteristic of masers in a thin, circumnuclear, edge-on accretion disk, and VLBI observations of these megamasers confirm the disk geometry. The maps reveal the size, shape (i.e. warp), and orientation of the disks, they provide gold-standard black hole masses and, in several cases, they enable the measurement of geometric distances to the host galaxies. In a few megamasers with more ambiguous single-dish profiles, VLBI maps show that some of the emission originates not in a disk, but rather from clouds that appear to be associated with an outflow. In these megamasers, and possibly many of the systems not yet mapped with VLBI, the masers may be directly associated with optically opaque, dusty gas believed to obscure some AGNs. Here we summarize results from VLBI imaging of megamasers and discuss the prospects for using observations of masers to understand the nature of obscuring gas in AGNs.

Overdensities of SMGs around WISE-selected, ultraluminous, high-redshift AGNs

NASA Astrophysics Data System (ADS)

Jones, Suzy F.; Blain, Andrew W.; Assef, Roberto J.; Eisenhardt, Peter; Lonsdale, Carol; Condon, James; Farrah, Duncan; Tsai, Chao-Wei; Bridge, Carrie; Wu, Jingwen; Wright, Edward L.; Jarrett, Tom

2017-08-01

We investigate extremely luminous dusty galaxies in the environments around Wide-field Infrared Survey Explorer (WISE)-selected hot dust-obscured galaxies (Hot DOGs) and WISE/radio-selected active galactic nuclei (AGNs) at average redshifts of z = 2.7 and 1.7, respectively. Previous observations have detected overdensities of companion submillimetre-selected sources around 10 Hot DOGs and 30 WISE/radio AGNs, with overdensities of ˜2-3 and ˜5-6, respectively. We find that the space densities in both samples to be overdense compared to normal star-forming galaxies and submillimetre galaxies (SMGs) in the Submillimetre Common-User Bolometer Array 2 (SCUBA-2) Cosmology Legacy Survey (S2CLS). Both samples of companion sources have consistent mid-infrared (mid-IR) colours and mid-IR to submm ratios as SMGs. The brighter population around WISE/radio AGNs could be responsible for the higher overdensity reported. We also find that the star formation rate densities are higher than the field, but consistent with clusters of dusty galaxies. WISE-selected AGNs appear to be good signposts for protoclusters at high redshift on arcmin scales. The results reported here provide an upper limit to the strength of angular clustering using the two-point correlation function. Monte Carlo simulations show no angular correlation, which could indicate protoclusters on scales larger than the SCUBA-2 1.5-arcmin scale maps.

Identifying the subtle signatures of feedback from distant AGN using ALMA observations and the EAGLE hydrodynamical simulations

NASA Astrophysics Data System (ADS)

Scholtz, J.; Alexander, D. M.; Harrison, C. M.; Rosario, D. J.; McAlpine, S.; Mullaney, J. R.; Stanley, F.; Simpson, J.; Theuns, T.; Bower, R. G.; Hickox, R. C.; Santini, P.; Swinbank, A. M.

2018-03-01

We present sensitive 870 μm continuum measurements from our ALMA programmes of 114 X-ray selected active galactic nuclei (AGN) in the Chandra Deep Field-South and Cosmic Evolution Survey fields. We use these observations in combination with data from Spitzer and Herschel to construct a sample of 86 X-ray selected AGN, 63 with ALMA constraints at z = 1.5-3.2 with stellar mass >2 × 1010 M⊙. We constructed broad-band spectral energy distributions in the infrared band (8-1000 μm) and constrain star-formation rates (SFRs) uncontaminated by the AGN. Using a hierarchical Bayesian method that takes into account the information from upper limits, we fit SFR and specific SFR (sSFR) distributions. We explore these distributions as a function of both X-ray luminosity and stellar mass. We compare our measurements to two versions of the Evolution and Assembly of GaLaxies and their Environments (EAGLE) hydrodynamical simulations: the reference model with AGN feedback and the model without AGN. We find good agreement between the observations and that predicted by the EAGLE reference model for the modes and widths of the sSFR distributions as a function of both X-ray luminosity and stellar mass; however, we found that the EAGLE model without AGN feedback predicts a significantly narrower width when compared to the data. Overall, from the combination of the observations with the model predictions, we conclude that (1) even with AGN feedback, we expect no strong relationship between the sSFR distribution parameters and instantaneous AGN luminosity and (2) a signature of AGN feedback is a broad distribution of sSFRs for all galaxies (not just those hosting an AGN) with stellar masses above ≈1010 M⊙.

The contribution of faint AGNs to the ionizing background at z 4

NASA Astrophysics Data System (ADS)

Grazian, A.; Giallongo, E.; Boutsia, K.; Cristiani, S.; Vanzella, E.; Scarlata, C.; Santini, P.; Pentericci, L.; Merlin, E.; Menci, N.; Fontanot, F.; Fontana, A.; Fiore, F.; Civano, F.; Castellano, M.; Brusa, M.; Bonchi, A.; Carini, R.; Cusano, F.; Faccini, M.; Garilli, B.; Marchetti, A.; Rossi, A.; Speziali, R.

2018-05-01

Context. Finding the sources responsible for the hydrogen reionization is one of the most pressing issues in observational cosmology. Bright quasi-stellar objects (QSOs) are known to ionize their surrounding neighborhood, but they are too few to ensure the required HI ionizing background. A significant contribution by faint active galactic nuclei (AGNs), however, could solve the problem, as recently advocated on the basis of a relatively large space density of faint active nuclei at z > 4. Aims: This work is part of a long-term project aimed at measuring the Lyman Continuum escape fraction for a large sample of AGNs at z 4 down to an absolute magnitude of M1450 -23. We have carried out an exploratory spectroscopic program to measure the HI ionizing emission of 16 faint AGNs spanning a broad U - I color interval, with I 21-23, and 3.6 < z < 4.2. These AGNs are three magnitudes fainter than the typical SDSS QSOs (M1450 ≲-26) which are known to ionize their surrounding IGM at z ≳ 4. Methods: We acquired deep spectra of these faint AGNs with spectrographs available at the VLT, LBT, and Magellan telescopes, that is, FORS2, MODS1-2, and LDSS3, respectively. The emission in the Lyman Continuum region, close to 900 Å rest frame, has been detected with a signal to noise ratio of 10-120 for all 16 AGNs. The flux ratio between the 900 Å rest-frame region and 930 Å provides a robust estimate of the escape fraction of HI ionizing photons. Results: We have found that the Lyman Continuum escape fraction is between 44 and 100% for all the observed faint AGNs, with a mean value of 74% at 3.6 < z < 4.2 and - 25.1 ≲ M1450 ≲-23.3, in agreement with the value found in the literature for much brighter QSOs (M1450 ≲-26) at the same redshifts. The Lyman Continuum escape fraction of our faint AGNs does not show any dependence on the absolute luminosities or on the observed U - I colors of the objects. Assuming that the Lyman Continuum escape fraction remains close to 75% down

Extragalactic gamma-ray background from AGN winds and star-forming galaxies in cosmological galaxy-formation models

NASA Astrophysics Data System (ADS)

Lamastra, A.; Menci, N.; Fiore, F.; Antonelli, L. A.; Colafrancesco, S.; Guetta, D.; Stamerra, A.

2017-10-01

We derive the contribution to the extragalactic gamma-ray background (EGB) from active galactic nuclei (AGN) winds and star-forming galaxies by including a physical model for the γ-ray emission produced by relativistic protons accelerated by AGN-driven and supernova-driven shocks into a state-of-the-art semi-analytic model of galaxy formation. This is based on galaxy interactions as triggers of AGN accretion and starburst activity and on expanding blast waves as the mechanism to communicate outwards the energy injected into the interstellar medium by the active nucleus. We compare the model predictions with the latest measurement of the EGB spectrum performed by the Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope (Fermi) in the range between 100 MeV and 820 GeV. We find that AGN winds can provide 35 ± 15% of the observed EGB in the energy interval Eγ = 0.1-1 GeV, for 73 ± 15% at Eγ = 1-10 GeV, and for 60 ± 20% at Eγ ≳10 GeV. The AGN wind contribution to the EGB is predicted to be larger by a factor of 3-5 than that provided by star-forming galaxies (quiescent plus starburst) in the hierarchical clustering scenario. The cumulative γ-ray emission from AGN winds and blazars can account for the amplitude and spectral shape of the EGB, assuming the standard acceleration theory, and AGN wind parameters that agree with observations. We also compare the model prediction for the cumulative neutrino background from AGN winds with the most recent IceCube data. We find that for AGN winds with accelerated proton spectral index p = 2.2-2.3, and taking into account internal absorption of γ-rays, the Fermi-LAT and IceCube data could be reproduced simultaneously.

FRESH ACTIVITY IN OLD SYSTEMS: RADIO AGNs IN FOSSIL GROUPS OF GALAXIES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hess, Kelley M.; Wilcots, Eric M.; Hartwick, Victoria L., E-mail: hess@ast.uct.ac.za, E-mail: ewilcots@astro.wisc.edu, E-mail: vhartwick@wisc.edu

2012-08-15

We present the first systematic 1.4 GHz Very Large Array radio continuum survey of fossil galaxy group candidates. These are virialized systems believed to have assembled over a gigayear in the past through the merging of galaxy group members into a single, isolated, massive elliptical galaxy and featuring an extended hot X-ray halo. We use new photometric and spectroscopic data from Sloan Digital Sky Survey Data Release 7 to determine that three of the candidates are clearly not fossil groups. Of the remaining 30 candidates, 67% contain a radio-loud (L{sub 1.4GHz} > 10{sup 23} W Hz{sup -1}) active galactic nucleusmore » (AGN) at the center of their dominant elliptical galaxy. We find a weak correlation between the radio luminosity of the AGN and the X-ray luminosity of the halo suggesting that the AGN contributes to energy deposition into the intragroup medium. We only find a correlation between the radio and optical luminosity of the central elliptical galaxy when we include X-ray-selected, elliptically dominated non-fossil groups, indicating a weak relationship between AGN strength and the mass assembly history of the groups. The dominant elliptical galaxy of fossil groups is on average roughly an order of magnitude more luminous than normal group elliptical galaxies in optical, X-ray, and radio luminosities and our findings are consistent with previous results that the radio-loud fraction in elliptical galaxies is linked to the stellar mass of a population. The current level of activity in fossil groups suggests that AGN fueling continues long after the last major merger. We discuss several possibilities for fueling the AGN at the present epoch.« less

BAT AGN Spectroscopic Survey (BASS) - VI. The ΓX-L/LEdd relation

NASA Astrophysics Data System (ADS)

Trakhtenbrot, Benny; Ricci, Claudio; Koss, Michael J.; Schawinski, Kevin; Mushotzky, Richard; Ueda, Yoshihiro; Veilleux, Sylvain; Lamperti, Isabella; Oh, Kyuseok; Treister, Ezequiel; Stern, Daniel; Harrison, Fiona; Baloković, Mislav; Gehrels, Neil

2017-09-01

We study the relation between accretion rate (in terms of L/LEdd) and shape of the hard X-ray spectral energy distribution (namely the photon index Γx) for a large sample of 228 hard X-ray-selected, low-redshift active galactic nuclei (AGNs), drawn from the Swift/BAT AGN Spectroscopic Survey (BASS). This includes 30 AGNs for which black hole mass (and therefore L/LEdd) is measured directly through masers, spatially resolved gas or stellar dynamics, or reverberation mapping. The high-quality and broad energy coverage of the data provided through BASS allow us to examine several alternative determinations of both Γx and L/LEdd. For the BASS sample as a whole, we find a statistically significant, albeit very weak correlation between Γx and L/LEdd. The best-fitting relations we find, Γx ≃ 0.15 log L/LEdd + const., are considerably shallower than those reported in previous studies. Moreover, we find no corresponding correlations among the subsets of AGN with different MBH determination methodology. In particular, we find no robust evidence for a correlation when considering only those AGN with direct or single-epoch MBH estimates. This latter finding is in contrast to several previous studies which focused on z > 0.5 broad-line AGN. We discuss this tension and conclude that it can be partially accounted for if one adopts a simplified, power-law X-ray spectral model, combined with L/LEdd estimates that are based on the continuum emission and on single-epoch broad-line spectroscopy in the optical regime. We finally highlight the limitations on using Γx as a probe of supermassive black hole evolution in deep extragalactic X-ray surveys.

Tracing the Far-Infrared Roles of AGN in Dusty Star-Forming Galaxies

NASA Astrophysics Data System (ADS)

Brown, Arianna; Nayyeri, Hooshang; Cooray, Asantha R.; Mitchell-Wynne, Ketron

2017-01-01

Active galactic nuclei (AGNs) are suggested to play an important role in quenching their host galaxy’s star formation rate (SFR) by heating up and/or consuming the cool gas necessary to create stars. This mechanism is theorized as a critical step in AGN evolutionary models. The efforts to study this effect suffer in part from low-number statistics at high x-ray luminosities (LXR > 1044 ergs/s) for AGNs at z≈1-3, and a lack of separately estimated SFRs for AGN in dusty, star-forming galaxies (DSFGs). In this work, we extend our analysis to build a more complete picture using the variety of available multi-wavelength data in the XBoötes region. The Chandra XBoötes Survey is a 5-ks X-ray survey of the 9.3 square degree Boötes Field of the NOAO Deep Wide-Field Survey, a survey imaged from the optical to the near-IR. We estimate AGN spectral energy distributions and SFRs for ~400 x-ray sources using available data in all four Spitzer IRAC bands, the Spitzer MIPS 24µm band, all five Herschel SPIRE and PACS bands, along with NEWFIRM optical bands. Preliminary results show an exponential correlation between x-ray luminosity and star formation. As a comparison, we will use a stacking technique for the ~500 x-ray sources that were not detected at submillimeter wavelengths, where sources are binned by x-ray luminosity. We will compare these two samples and expect to see a difference in slope. Using these techniques, we hope to place tighter constraints on the mean SFRs of high-luminosity AGNs inside DSFGs, and determine if x-ray luminosities are independent of average SFRs for our sample in the Boötes field.

Spatial clustering and halo occupation distribution modelling of local AGN via cross-correlation measurements with 2MASS galaxies

NASA Astrophysics Data System (ADS)

Krumpe, Mirko; Miyaji, Takamitsu; Coil, Alison L.; Aceves, Hector

2018-02-01

We present the clustering properties and halo occupation distribution (HOD) modelling of very low redshift, hard X-ray-detected active galactic nuclei (AGN) using cross-correlation function measurements with Two-Micron All Sky Survey galaxies. Spanning a redshift range of 0.007 < z < 0.037, with a median z = 0.024, we present a precise AGN clustering study of the most local AGN in the Universe. The AGN sample is drawn from the SWIFT/BAT 70-month and INTEGRAL/IBIS eight year all-sky X-ray surveys and contains both type I and type II AGN. We find a large-scale bias for the full AGN sample of b=1.04^{+0.10}_{-0.11}, which corresponds to a typical host dark matter halo mass of M_h^typ=12.84^{+0.22}_{-0.30} h^{-1} M_{⊙}. When split into low and high X-ray luminosity and type I and type II AGN subsamples, we detect no statistically significant differences in the large-scale bias parameters. However, there are differences in the small-scale clustering, which are reflected in the full HOD model results. We find that low and high X-ray luminosity AGN, as well as type I and type II AGN, occupy dark matter haloes differently, with 3.4σ and 4.0σ differences in their mean halo masses, respectively, when split by luminosity and type. The latter finding contradicts a simple orientation-based AGN unification model. As a by-product of our cross-correlation approach, we also present the first HOD model of 2MASS galaxies.

Changes in the clinical presentation of immunoglobulin A nephropathy: data from the Spanish Registry of Glomerulonephritis.

PubMed

Gutiérrez, Eduardo; Praga, Manuel; Rivera, Francisco; Sevillano, Angel; Yuste, Claudia; Goicoechea, Marian; López-Gómez, Juan M

2018-03-01

Immunoglobulin A nephropathy (IgAN) is the most common glomerulonephritis in the world, but there is little epidemiological data about possible changes in its presentation over the years. Available information about the influence of age on the form of clinical presentation is also scarce. The aim of the study was to analyse all renal biopsies performed between 1994 and 2013 and recorded in the Spanish Registry of Glomerulonephritis with a histological diagnosis of IgAN. The study was divided into five 4-year periods (1994-97, 1998-2001, 2002-05, 2006-09 and 2010-13) and patients were divided into four age groups: ≤16, 17-44, 45-64 and ≥65 years. From 20.974 renal biopsies recorded, 2961 (14.1%) corresponded to IgAN. The prevalence of IgAN remained stable, but a significant increase in age [from 37.6 (SD 17.7) in 1994-97 to 44.9 (SD 16.8) years in 2010-13; P = 0.001] and worse renal function at presentation [from serum creatinine (SCr) 1.9 (SD 1.9) in 1994-97 to 2.3 (SD 2.1) mg/dL in 2010-13; P = 0.001] were observed over the years. Nephrotic-range proteinuria and acute kidney injury (AKI) as forms of presentation were significantly more common among patients ≥65 years (17.7% and 43.2%, respectively) as compared with the other age groups [≤16 (11.4% and 13.1%, respectively), 17-44 (13.1% and 13%, respectively) and 45-64 (12.1% and 21.3%, respectively)]. Blood pressure, SCr and proteinuria were also significantly higher at presentation among elderly patients. Although the prevalence of IgAN in Spain has remained stable over the years, patients are significantly older and present with significantly worse renal function in the last years. The incidence of nephrotic-range proteinuria (17.7%) and AKI (43.2%) as forms of presentation is remarkable among patients ≥65 years of age. © The Author 2017. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

Tending the Fire, A Legacy Survey of Molecular Gas Fueling in Powerful Nearby AGN

NASA Astrophysics Data System (ADS)

Koss, Michael; BASS Team

2018-01-01

Over the last 30 years the importance of host galaxy molecular gas for growing black holes has been intensely debated. We have observed a a volume-limited sample of over 200 nearby powerful AGN (0.01 < z < 0.05, Lbol;AGN > 10^44 erg/s) using the CO 2-1 line with the JCMT and APEX telescopes to definitively address this issue. The AGN are selected from the Swift-BAT all sky hard X-ray survey which is superior to optical or IR selection since high energy X-rays (14-195 keV) are almost independent of host galaxy properties and obscuration. We compare our samples molecular gas properties to inactive galaxies selected with the IRAM 30m COLD GASS survey to understand the general trends with AGN activity.

The Evolutionary Connection Bewtween z~2-3 Submillimeter Galaxies and AGN as Probed by Molecular Gas Excitation

NASA Astrophysics Data System (ADS)

Sharon, Chelsea E.; Riechers, Dominik A.; Carilli, Chris Luke; Hodge, Jacqueline; Walter, Fabian

2016-01-01

Theoretical work has suggested that active galactic nuclei (AGN) play an important role in quenching star formation in massive galaxies. Direct evidence for AGN affecting the molecular ISM has so far been limited to detections of molecular outflows in low-redshift systems and extreme excitation regions which represent a tiny fraction of the total gas. Indirect evidence for AGN's impact on their host galaxies' cold gas phase may be provided by measurements of the gas excitation and dynamics. At z~2-3, the peak epoch of star formation and AGN activity, previous observations of the CO(1-0) line revealed that submillimeter galaxies (SMGs) have multi-phase molecular gas, including substantial reservoirs of cold-phase gas. However, the entirety of the molecular gas in AGN-host galaxies appears highly excited, potentially supporting an evolutionary connection between these two populations. I will present a new VLA sample that nearly doubles the number of CO(1-0) detections in z~2-3 SMGs and AGN-host galaxies that allows us to better compare the cold gas properties of these systems and further investigate evidence for the effects of AGN on the star-forming molecular gas.

Compton-thick AGNs in the NuSTAR Era

NASA Astrophysics Data System (ADS)

Marchesi, S.; Ajello, M.; Marcotulli, L.; Comastri, A.; Lanzuisi, G.; Vignali, C.

2018-02-01

We present the 2–100 keV spectral analysis of 30 candidate Compton-thick-(CT-)active galactic nuclei (AGNs) selected in the Swift-Burst Alert Telescope (BAT) 100 month survey. The average redshift of these objects is < z> ∼ 0.03, and they all lie within ∼500 Mpc. We used the MyTorus model to perform X-ray spectral fittings both without and with the contribution of the Nuclear Spectroscopic Telescope Array (NuSTAR) data in the 3–50 keV energy range. When the NuSTAR data are added to the fit, 13 out of 30 of these objects (43% of the whole sample) have intrinsic absorption N H < 1024 cm‑2 at the >3σ confidence level, i.e., they are reclassified from Compton thick to Compton thin. Consequently, we infer an overall observed fraction of the CT-AGN, with respect to the whole AGN population, lower than the one reported in previous works, as low as ∼4%. We find evidence that this overestimation of N H is likely due to the low quality of a subsample of spectra, either in the 2–10 keV band or in the Swift-BAT one.

NGC 3393: multi-component AGN feedback as seen by CHEERS

NASA Astrophysics Data System (ADS)

Maksym, W. Peter; Fabbiano, Giuseppina; Elvis, Martin; Karovska, Margarita; Raymond, John C.; Storchi-Bergmann, Thaisa; Paggi, Alessandro; Wang, Junfeng; Risaliti, Guido

2017-01-01

Due to its low density, moderate ionization, and weak kinematics, the narrow line region (NLR) of active galactic nuclei (AGN) provides poweful diagnostics for investigating AGN feedback. The CHandra Extended Emission line Region Survey (CHEERS) is the ultimate investigation into resolved feedback in the NLR. We present results from our CHEERS investigations of NGC 3393. By imaging extended X-ray line emission of NGC 3393 with Chandra and optical line emission with Hubble's narrow-band filters, we are able to map out the simultaneous impact of photoionization, jets and an AGN disk-wind. When resolved on scales of ~10s of parsecs, the NLR of NGC 3393 shows a complex multi-component medium. Diagnostic line mapping indicates a Low-ionization Emmision Line Region (LINER) cocoon surrounding the outflow-evacuated cavities (in optical) and surrounding the supports the presence of collisional plasma (in X-rays). These physically distinct constituent regions can only be resolved by the high-resolution imaging that Chandra and HST enable.

An Antifungal Exo-α-1,3-Glucanase (AGN13.1) from the Biocontrol Fungus Trichoderma harzianum

PubMed Central

Ait-Lahsen, Hassane; Soler, Andrés; Rey, Manuel; de la Cruz, Jesús; Monte, Enrique; Llobell, Antonio

2001-01-01

Trichoderma harzianum secretes α-1,3-glucanases when it is grown on polysaccharides, fungal cell walls, or autoclaved mycelium as a carbon source (simulated antagonistic conditions). We have purified and characterized one of these enzymes, named AGN13.1. The enzyme was monomeric and slightly basic. AGN13.1 was an exo-type α-1,3-glucanase and showed lytic and antifungal activity against fungal plant pathogens. Northern and Western analyses indicated that AGN13.1 is induced by conditions that simulated antagonism. We propose that AGN13.1 contributes to the antagonistic response of T. harzianum. PMID:11722942

Hypercat - Hypercube of AGN tori

NASA Astrophysics Data System (ADS)

Nikutta, Robert; Lopez-Rodriguez, Enrique; Ichikawa, Kohei; Levenson, Nancy A.; Packham, Christopher C.

2018-06-01

AGN unification and observations hold that a dusty torus obscures the central accretion engine along some lines of sight. SEDs of dust tori have been modeled for a long time, but resolved emission morphologies have not been studied in much detail, because resolved observations are only possible recently (VLTI,ALMA) and in the near future (TMT,ELT,GMT). Some observations challenge a simple torus model, because in several objects most of MIR emission appears to emanate from polar regions high above the equatorial plane, i.e. not where the dust supposedly resides.We introduce our software framework and hypercube of AGN tori (Hypercat) made with CLUMPY (www.clumpy.org), a large set of images (6 model parameters + wavelength) to facilitate studies of emission and dust morphologies. We make use of Hypercat to study the morphological properties of the emission and dust distributions as function of model parameters. We find that a simple clumpy torus can indeed produce 10-micron emission patterns extended in polar directions, with extension ratios compatible with those found in observations. We are able to constrain the range of parameters that produce such morphologies.

The jets of AGN as giant coaxial cables

NASA Astrophysics Data System (ADS)

Gabuzda, Denise C.; Nagle, Matt; Roche, Naomi

2018-04-01

Context. The currents carried by the jets of active galactic nuclei (AGNs) can be probed using maps of the Faraday rotation measure (RM), since a jet current will be accompanied by a toroidal magnetic field, which will give rise to a systematic change in the RM across the jet. Aims: The aim of this study is to identify new AGNs displaying statistically significant transverse RM gradients across their parsec-scale jets, in order to determine how often helical magnetic fields occur in AGN jets, and to look for overall patterns in the implied directions for the toroidal field components and jet currents. Methods: We have carried out new analyses of Faraday RM maps derived from previously published 8.1, 8.4, 12.1 and 15.3 GHz data obtained in 2006 on the NRAO Very Long Baseline Array (VLBA). In a number of key ways, our procedures were identical to those of the original authors, but the new imaging and analysis differs from the original methods in several ways: the technique used to match the resolutions at the different frequencies, limits on the widths spanned by the RM gradients analyzed, treatment of core-region RM gradients, approach to estimation of the significances of the gradients analyzed, and inclusion of a supplementary analysis using circular beams with areas equal to those of the corresponding elliptical naturally weighted beams. Results: This new analysis has substantially increased the number of AGNs known to display transverse RM gradients that may reflect the presence of a toroidal magnetic-field component. The collected data on parsec and kiloparsec scales indicate that the current typically flows inward along the jet axis and outward in a more extended region surrounding the jet, typical to the current structure of a co-axial cable, accompanied by a self-consistent system of nested helical magnetic fields, whose toroidal components give rise to the observed transverse Faraday rotation gradients. Conclusions: The new results presented here make it

AGES: THE AGN AND GALAXY EVOLUTION SURVEY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kochanek, C. S.; Eisenstein, D. J.; Caldwell, N.

2012-05-01

The AGN and Galaxy Evolution Survey (AGES) is a redshift survey covering, in its standard fields, 7.7 deg{sup 2} of the Booetes field of the NOAO Deep Wide-Field Survey. The final sample consists of 23,745 redshifts. There are well-defined galaxy samples in 10 bands (the B{sub W} , R, I, J, K, IRAC 3.6, 4.5, 5.8, and 8.0 {mu}m, and MIPS 24 {mu}m bands) to a limiting magnitude of I < 20 mag for spectroscopy. For these galaxies, we obtained 18,163 redshifts from a sample of 35,200 galaxies, where random sparse sampling was used to define statistically complete sub-samples inmore » all 10 photometric bands. The median galaxy redshift is 0.31, and 90% of the redshifts are in the range 0.085 < z < 0.66. Active galactic nuclei (AGNs) were selected as radio, X-ray, IRAC mid-IR, and MIPS 24 {mu}m sources to fainter limiting magnitudes (I < 22.5 mag for point sources). Redshifts were obtained for 4764 quasars and galaxies with AGN signatures, with 2926, 1718, 605, 119, and 13 above redshifts of 0.5, 1, 2, 3, and 4, respectively. We detail all the AGES selection procedures and present the complete spectroscopic redshift catalogs and spectral energy distribution decompositions. Photometric redshift estimates are provided for all sources in the AGES samples.« less

Serial Manifestation of Acute Kidney Injury and Nephrotic Syndrome in a Patient with TAFRO syndrome.

PubMed

Ito, Seigo; Uchida, Takahiro; Itai, Hiroki; Yamashiro, Aoi; Yamagata, Akira; Matsubara, Hidehito; Imakiire, Toshihiko; Shimazaki, Hideyuki; Kumagai, Hiroo; Oshima, Naoki

2018-06-06

A 76-year-old woman suddenly developed anasarca and a fever, and an examination revealed thrombocytopenia, reticulin fibrosis, and acute kidney injury, yielding the diagnosis of TAFRO syndrome. Renal replacement therapy and steroid treatment were soon started. Her proteinuria was minor at first; however, once the kidney function improved, nephrotic syndrome occurred. A kidney biopsy showed membranoproliferative glomerulonephritis-like glomerulopathy with massive macrophage infiltration. Although kidney dysfunction is often observed in TAFRO syndrome patients, its detailed mechanism is unclear. This case suggests that TAFRO syndrome involves both acute kidney injury with minor proteinuria and nephrotic syndrome, and these disorders can develop serially in the same patient.

Continuum Reverberation Mapping of AGN Accretion Disks

NASA Astrophysics Data System (ADS)

Fausnaugh, Michael M.; Peterson, Bradley M.; Starkey, David A.; Horne, Keith; AGN Storm Collaboration

2017-12-01

We show recent detections of inter-band continuum lags in three AGN (NGC 5548, NGC 2617, and MCG+08-11-011), which provide new constraints on the temperature profiles and absolute sizes of the accretion disks. We find lags larger than would be predicted for standard geometrically thin, optically thick accretion disks by factors of 2.3 to 3.3. For NGC 5548, the data span UV through optical/near-IR wavelengths, and we are able to discern a steeper temperature profile than the T˜ R^{-3/4} expected for a standard thin disk . Using a physical model, we are also able to estimate the inclinations of the disks for two objects. These results are similar to those found from gravitational microlensing of strongly lensed quasars, and provide a complementary approach for investigating the accretion disk structure in local, low luminsoity AGN.

X-ray and Ultraviolet Properties of AGNs in Nearby Dwarf Galaxies

NASA Astrophysics Data System (ADS)

Baldassare, Vivienne F.; Reines, Amy E.; Gallo, Elena; Greene, Jenny E.

2017-02-01

We present new Chandra X-ray Observatory and Hubble Space Telescope observations of eight optically selected broad-line active galactic nucleus (AGN) candidates in nearby dwarf galaxies (z < 0.055). Including archival Chandra observations of three additional sources, our sample contains all 10 galaxies from Reines et al. (2013) with both broad Hα emission and narrow-line AGN ratios (six AGNs, four composites), as well as one low-metallicity dwarf galaxy with broad Hα and narrow-line ratios characteristic of star formation. All 11 galaxies are detected in X-rays. Nuclear X-ray luminosities range from L 0.5-7keV ≈ 5 × 1039 to 1 × 1042 ergs-1. In all cases except for the star-forming galaxy, the nuclear X-ray luminosities are significantly higher than would be expected from X-ray binaries, providing strong confirmation that AGNs and composite dwarf galaxies do indeed host actively accreting black holes (BHs). Using our estimated BH masses (which range from ˜7 × 104 to 1 × 106 M ⊙), we find inferred Eddington fractions ranging from ˜0.1% to 50%, I.e., comparable to massive broad-line quasars at higher redshift. We use the HST imaging to determine the ratio of UV to X-ray emission for these AGNs, finding that they appear to be less X-ray luminous with respect to their UV emission than more massive quasars (I.e., α OX values an average of 0.36 lower than expected based on the relation between α OX and 2500 Å luminosity). Finally, we discuss our results in the context of different accretion models onto nuclear BHs.

Seeing Through the Clouds: AGN Geometry with the Swift BAT Sample

NASA Astrophysics Data System (ADS)

Glikman, Eilat; Urry, M.; Schawinski, K.; Koss, M. J.; Winter, L. M.; Elitzur, M.; Wilkin, W. H.

2011-01-01

We investigate the intrinsic structure of the clouds surrounding AGN which give rise to their X-ray and optical emission properties. Using a complete sample of Swift BAT AGN selected in hard X-rays (14-195 keV), which is unbiased with respect to obscuration and extinction, we compute the reddening in the broad line region along the line of sight to the nucleus of each source using Balmer decrement from the ratio of the broad components of H-alpha/H-beta. We compare reddening from dust in the broad line clouds to the hydrogen column density (NH) obtained from their X-ray spectra. The distribution of the gas-to-dust ratios over many lines of sight allow us to test models of AGN structure and probe the immediate environment of the accreting supermassive black holes.

Exploring the Connection Between Star Formation and AGN Activity in the Local Universe

NASA Technical Reports Server (NTRS)

LaMassa, Stephanie M.; Heckman. T. M.; Ptak, Andrew; Schiminovich, D.; O'Dowd, M.; Bertincourt, B.

2012-01-01

We study a combined sample of 264 star-forming, 51 composite, and 73 active galaxies using optical spectra from SDSS and mid-infrared (mid-IR) spectra from the Spitzer Infrared Spectrograph. We examine optical and mid-IR spectroscopic diagnostics that probe the amount of star formation and relative energetic con- tributions from star formation and an active galactic nucleus (AGN). Overall we find good agreement between optical and mid-IR diagnostics. Misclassifications of galaxies based on the SDSS spectra are rare despite the presence of dust obscuration. The luminosity of the [NeII] 12.8 micron emission-line is well correlated with the star formation rate (SFR) measured from the SDSS spectra, and this holds for the star forming, composite, and AGN-dominated systems. AGN show a clear excess of [NeIII] 15.6 micron emission relative to star forming and composite systems. We find good qualitative agreement between various parameters that probe the relative contributions of the AGN and star formation, including: the mid-IR spectral slope, the ratio of the [NeV] 14.3 micron to [NeII] micron 12.8 fluxes, the equivalent widths of the 7.7, 11.3, and 17 micron PAH features, and the optical "D" parameter which measures the distance a source lies from the locus of star forming galaxies in the optical BPT emission-line diagnostic diagram. We also consider the behavior of the three individual PAH features by examining how their flux ratios depend upon the degree of AGN-dominance. We find that the PAH 11.3 micron feature is significantly suppressed in the most AGN-dominated systems.

AGN Obscuration Through Dusty Infrared Dominated Flows. II. Multidimensional, Radiation-Hydrodynamics Modeling

NASA Technical Reports Server (NTRS)

Dorodnitsyn, Anton; Kallman, Tim; Bisno\\vatyiI-Kogan, Gennadyi

2011-01-01

We explore a detailed model in which the active galactic nucleus (AGN) obscuration results from the extinction of AGN radiation in a global ow driven by the pressure of infrared radiation on dust grains. We assume that external illumination by UV and soft X-rays of the dusty gas located at approximately 1pc away from the supermassive black hole is followed by a conversion of such radiation into IR. Using 2.5D, time-dependent radiation hydrodynamics simulations in a ux-limited di usion approximation we nd that the external illumination can support a geometrically thick obscuration via out ows driven by infrared radiation pressure in AGN with luminosities greater than 0:05 L(sub edd) and Compton optical depth, Tau(sub T) approx > & 1.

Dynamics and formation of obscuring tori in AGNs

NASA Astrophysics Data System (ADS)

Bannikova, Elena Yu.; Sergeyev, Alexey V.

2017-12-01

We considered the evolution of a self-gravitating clumpy torus in the gravitational field of the central mass of an active galactic nucleus (AGN) in the framework of the N-body problem. The initial conditions take into account winds with different opening angles. Results of our N-body simulations show that the clouds moving on orbits with a spread in inclinations and eccentricities form a toroidal region. This mechanism can solve the problem of the geometrical thickness of the torus. The velocity of the clouds at the inner edge of the torus is lower than in a disk model that can explain the observed rotation curves. We discuss the scenario of torus formation related with the beginning of the AGN stage.

The X-Ray Background and the AGN Luminosity Function

NASA Astrophysics Data System (ADS)

Hasinger, G.

The deepest X-ray surveys performed with ROSAT were able to resolve as much as 70-80% of the 1-2 keV X-ray background into resolved sources. Optical follow-up observations were able to identify the majority of faint X-ray sources as active galactic nuclei (AGN) out to redshifts of 4.5 as well as a sizeable fraction as groups of galaxies out to redshifts of 0.7. A new population of X-ray luminous, optically innocent narrow emission line galaxies (NELGs) at the faintest X-ray fluxes is still a matter of debate, most likely many of them are also connected to AGN. First deep surveys with the Japanese ASCA satellite give us a glimpse of the harder X-ray background where the bulk of the energy density resides. Future X-ray observatories (XMM and AXAF) will be able to resolve the harder X-ray background. For the first time we are now in a position to study the cosmological evolution of the X-ray luminosity function of AGN, groups of galaxies and galaxies and simultaneously constrain their total luminosity output over cosmic time.

The Kepler Light Curves of AGN: A Detailed Analysis

DOE PAGES

Smith, Krista Lynne; Mushotzky, Richard F.; Boyd, Patricia T.; ...

2018-04-25

Here, we present a comprehensive analysis of 21 light curves of Type 1 active galactic nuclei (AGN) from the Kepler spacecraft. First, we describe the necessity and development of a customized pipeline for treating Kepler data of stochastically variable sources like AGN. We then present the light curves, power spectral density functions (PSDs), and flux histograms. The light curves display an astonishing variety of behaviors, many of which would not be detected in ground-based studies, including switching between distinct flux levels. Six objects exhibit PSD flattening at characteristic timescales that roughly correlate with black hole mass. These timescales are consistentmore » with orbital timescales or free-fall accretion timescales. We check for correlations of variability and high-frequency PSD slope with accretion rate, black hole mass, redshift, and luminosity. We find that bolometric luminosity is anticorrelated with both variability and steepness of the PSD slope. We do not find evidence of the linear rms–flux relationships or lognormal flux distributions found in X-ray AGN light curves, indicating that reprocessing is not a significant contributor to optical variability at the 0.1%–10% level.« less

The Kepler Light Curves of AGN: A Detailed Analysis

NASA Astrophysics Data System (ADS)

Smith, Krista Lynne; Mushotzky, Richard F.; Boyd, Patricia T.; Malkan, Matt; Howell, Steve B.; Gelino, Dawn M.

2018-04-01

We present a comprehensive analysis of 21 light curves of Type 1 active galactic nuclei (AGN) from the Kepler spacecraft. First, we describe the necessity and development of a customized pipeline for treating Kepler data of stochastically variable sources like AGN. We then present the light curves, power spectral density functions (PSDs), and flux histograms. The light curves display an astonishing variety of behaviors, many of which would not be detected in ground-based studies, including switching between distinct flux levels. Six objects exhibit PSD flattening at characteristic timescales that roughly correlate with black hole mass. These timescales are consistent with orbital timescales or free-fall accretion timescales. We check for correlations of variability and high-frequency PSD slope with accretion rate, black hole mass, redshift, and luminosity. We find that bolometric luminosity is anticorrelated with both variability and steepness of the PSD slope. We do not find evidence of the linear rms–flux relationships or lognormal flux distributions found in X-ray AGN light curves, indicating that reprocessing is not a significant contributor to optical variability at the 0.1%–10% level.

The Kepler Light Curves of AGN: A Detailed Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, Krista Lynne; Mushotzky, Richard F.; Boyd, Patricia T.

Here, we present a comprehensive analysis of 21 light curves of Type 1 active galactic nuclei (AGN) from the Kepler spacecraft. First, we describe the necessity and development of a customized pipeline for treating Kepler data of stochastically variable sources like AGN. We then present the light curves, power spectral density functions (PSDs), and flux histograms. The light curves display an astonishing variety of behaviors, many of which would not be detected in ground-based studies, including switching between distinct flux levels. Six objects exhibit PSD flattening at characteristic timescales that roughly correlate with black hole mass. These timescales are consistentmore » with orbital timescales or free-fall accretion timescales. We check for correlations of variability and high-frequency PSD slope with accretion rate, black hole mass, redshift, and luminosity. We find that bolometric luminosity is anticorrelated with both variability and steepness of the PSD slope. We do not find evidence of the linear rms–flux relationships or lognormal flux distributions found in X-ray AGN light curves, indicating that reprocessing is not a significant contributor to optical variability at the 0.1%–10% level.« less

The clustering and bias of radio-selected AGN and star-forming galaxies in the COSMOS field

NASA Astrophysics Data System (ADS)

Hale, C. L.; Jarvis, M. J.; Delvecchio, I.; Hatfield, P. W.; Novak, M.; Smolčić, V.; Zamorani, G.

2018-03-01

Dark matter haloes in which galaxies reside are likely to have a significant impact on their evolution. We investigate the link between dark matter haloes and their constituent galaxies by measuring the angular two-point correlation function of radio sources, using recently released 3 GHz imaging over ˜2 deg2 of the Cosmological Evolution Survey (COSMOS) field. We split the radio source population into star-forming galaxies (SFGs) and active galactic nuclei (AGN), and further separate the AGN into radiatively efficient and inefficient accreters. Restricting our analysis to z < 1, we find SFGs have a bias, b = 1.5 ^{+0.1}_{-0.2}, at a median redshift of z = 0.62. On the other hand, AGN are significantly more strongly clustered with b = 2.1 ± 0.2 at a median redshift of 0.7. This supports the idea that AGN are hosted by more massive haloes than SFGs. We also find low accretion rate AGN are more clustered (b = 2.9 ± 0.3) than high accretion rate AGN (b = 1.8^{+0.4}_{-0.5}) at the same redshift (z ˜ 0.7), suggesting that low accretion rate AGN reside in higher mass haloes. This supports previous evidence that the relatively hot gas that inhabits the most massive haloes is unable to be easily accreted by the central AGN, causing them to be inefficient. We also find evidence that low accretion rate AGN appear to reside in halo masses of Mh ˜ 3-4 × 1013 h-1 M⊙ at all redshifts. On the other hand, the efficient accreters reside in haloes of Mh ˜ 1-2 × 1013 h-1 M⊙ at low redshift but can reside in relatively lower mass haloes at higher redshifts. This could be due to the increased prevalence of cold gas in lower mass haloes at z ≥ 1 compared to z < 1.

The first 62 AGNs observed with SDSS-IV MaNGA - I. Their characterization and definition of a control sample

NASA Astrophysics Data System (ADS)

Rembold, Sandro B.; Shimoia, Jáderson S.; Storchi-Bergmann, Thaisa; Riffel, Rogério; Riffel, Rogemar A.; Mallmann, Nícolas D.; do Nascimento, Janaína C.; Moreira, Thales N.; Ilha, Gabriele S.; Machado, Alice D.; Cirolini, Rafael; da Costa, Luiz N.; Maia, Marcio A. G.; Santiago, Basílio X.; Schneider, Donald P.; Wylezalek, Dominika; Bizyaev, Dmitry; Pan, Kaike; Müller-Sánchez, Francisco

2017-12-01

We report the characterization of the first 62 Mapping Nearby Galaxies at the Apache Point Observatory active galactic nuclei (AGNs) hosts and the definition of a control sample of non-active galaxies. This control sample was selected in order to match the AGN hosts in terms of stellar mass, redshift, visual morphology and inclination. The stellar masses are in the range 9.4AGN sample is mostly comprised low-luminosity AGN, with only 17 'strong AGN' with L([O III]λ 5007°_A ≥ 3.8× 10^{40} erg s^{-1}. The inner 1-3 kpc of the control sample galaxies are dominated by the oldest (≥ 4 Gyr) component, with a small contribution of intermediate age and young stars (<940 Myr). Examining the relationship between the stellar population properties and L([O III]}), we find that with increasing L([O III]), the AGN exhibit a decreasing contribution from the oldest stellar population relative to control galaxies and an increasing contribution from the younger components (∼40 Myr). We also find a correlation of the mean age differences (AGN-control) with L([O III]), in the sense that more luminous AGNs are younger than the control objects, while the low-luminosity AGNs are older. These results support a connection between the growth of the galaxy bulge via formation of new stars and the growth of the Supermassive Black Hole via accretion in the AGN phase.

Simultaneous Chandra and NuSTAR Observations of the Highly Obscured AGN Candidate in NGC660.

NASA Astrophysics Data System (ADS)

Annuar, Ady

2014-09-01

We are using NuSTAR to undertake a detailed investigation of the obscured AGN population at D<15Mpc. Our latest target is NGC660 where the presence of an AGN has been ambiguous. However, recently it was observed to undergo a radio outburst which reveals a bright continuum source (Argo et al. 2015), coincident with Chandra 2-8 keV emission from one of the three point sources near the nucleus (<5"). This confirms and pinpoints the X-ray position of the AGN. Comparisons of the Chandra flux with the radio emission and other multiwavelength luminosity indicators indicate that the X-ray flux is suppressed, suggesting that it is absorbed by a high column of gas. A NuSTAR observation for this object has been scheduled as part of our program. The requested Chandra observation is essential to unambiguously constrain the AGN and isolate it from other sources at <8 keV. When combined with NuSTAR, we will then be able to accurately characterise the 0.5-30 keV spectrum of the AGN for the first time.

Do Radio Jets Contribute to Driving Ionized Gas Outflows in Moderate Luminosity Type 2 AGN?

NASA Astrophysics Data System (ADS)

Fowler, Julia; Sajina, Anna; Lacy, Mark

2016-01-01

This poster examines the role of AGN-driven feedback in low to intermediate power radio galaxies. We begin with [OIII] measurements of ionized gas outflows in 29 moderate AGN-luminosity z~0.3-0.7 dust-obscured Type 2 AGN. We aim to examine the relative role of the AGN itself, of star-formation and of nascent radio jets in driving these outflows. The strength of the AGN and star formation are based on the [OIII] luminosities, and the far-IR luminosities respectively. For the radio jets, we present multi-frequency radio (X, S, and L-bands) JVLA imaging of our sample, which allows us both to constrain the overall radio power, but also look for signatures of young radio sources, including Giga-hertz Peaked Spectrum (GPS) sources, as well as small-scale jets. While radio jet-driven outflows are well known for powerful radio-loud galaxies, this study allows us to constrain the degree to which this mechanism is significant at more modest radio luminosities of L5GHz~10^22-25 W/Hz.

Optical variability properties of the largest AGN sample observed with Kepler/K2

NASA Astrophysics Data System (ADS)

Aranzana, E.; Koerding, E.; Uttley, P.; Scaringi, S.; Steven, B.

2017-10-01

We present the first short time-scale ( hours to days) optical variability study of a large sample of Active Galactic Nuclei (AGN) observed with the Kepler/K2 mission. The sample contains 275 AGN observed over four campaigns with ˜30-minute cadence selected from the Million Quasar Catalogue with R magnitude < 19. We performed time series analysis to determine their variability properties by means of the power spectral densities (PSDs) and applied Monte Carlo techniques to find the best model parameters that fit the observed power spectra. A power-law model is sufficient to describe all the PSDs of the AGN in our sample. The average power-law slope is 2.5±0.5, steeper than the PSDs observed in X-rays, and the rest-frame amplitude variability in the frequency range of 6×10^{-6}-10^{-4} Hz varies from 1-10 % with an average of 2.6 %. We explore correlations between the variability amplitude and key parameters of the AGN, finding a significant correlation of rest-frame short-term variability amplitude with redshift, but no such correlation with luminosity. We attribute these effects to the known 'bluer when brighter variability of quasars combined with the fixed bandpass of Kepler. This study enables us to distinguish between Seyferts and Blazar and confirm AGN candidates.

Is Black Hole Growth a Universal Process? Exploring Selection Effects in Measurements of AGN Accretion Rates and Host Galaxies.

NASA Astrophysics Data System (ADS)

Jones, Mackenzie

2018-01-01

At the center of essentially every massive galaxy is a monstrous black hole producing luminous radiation driven by the accretion of gas. By observing these active galactic nuclei (AGN) we may trace the growth of black holes across cosmic time. However, our knowledge of the full underlying AGN population is hindered by complex observational biases. My research aims to untangle these biases by using a novel approach to simulate the impact of selection effects on multiwavelength observations.The most statistically powerful studies of AGN to date come from optical spectroscopic surveys, with some reporting a complex relationship between AGN accretion rates and host galaxy characteristics. However, the optical waveband can be strongly influenced by selection effects and dilution from host galaxy star formation. I have shown that accounting for selection effects, the Eddington ratio distribution for optically-selected AGN is consistent with a broad power-law, as seen in the X-rays (Jones et al. 2016). This suggests that a universal Eddington ratio distribution may be enough to describe the full multiwavelength AGN population.Building on these results, I have expanded a semi-numerical galaxy formation simulation to include this straightforward prescription for AGN accretion and explicitly model selection effects. I have found that a simple model for AGN accretion can broadly reproduce the host galaxies and halos of X-ray AGN, and that different AGN selection techniques yield samples with very different host galaxy properties (Jones et al. 2017). Finally, I will discuss the capabilities of this simulation to build synthetic multiwavelength SEDs in order to explore what AGN populations would be detected with the next generation of observatories. This research is supported by a NASA Jenkins Graduate Fellowship under grant no. NNX15AU32H.

Hydrocarbon exposure may cause glomerulonephritis and worsen renal function: evidence based on Hill's criteria for causality.

PubMed

Ravnskov, U

2000-08-01

Many observational and experimental studies point to hydrocarbon exposure as an important pathogenic factor in glomerulonephritis. The findings have made little impact on current concepts and patient care, possibly because the hypothesis of a direct causal effect of the exposure and the hypothesis that the exposure worsens renal function have not been considered separately. This review examines these two hypotheses using Hill's criteria for causality. The results from 14 cross-sectional, 18 case-control studies, two cohort studies, 15 experiments on laboratory animals and two on human beings together with many case reports satisfy all but one of Hill's criteria for both hypotheses. Of particular importance is the finding in the case-control and follow-up studies of an association between degree of exposure and stage of renal disease, and an inverse association between degree of exposure and renal function, indicating that the most important effect of hydrocarbon exposure is its effect on renal function. End-stage renal failure may be preventable in many patients with glomerulonephritis provided a possible exposure to toxic chemicals is discontinued.

Dissecting the Butterfly: Dual Outflows in the Dual AGN NGC 6240

NASA Astrophysics Data System (ADS)

Mueller Sanchez, Francisco; Comerford, Julie; Nevin, Rebecca; Davies, Richard; Treister, Ezequiel; Privon, George

2018-01-01

Current theories of galaxy evolution invoke some kind of feedback (from the stars or the supermassive black hole) to explain the properties of galaxies. However, numerical simulations and observations have not been able to evaluate the real impact of feedback in galaxies. This is largely because most studies have focused on studying stellar feedback or AGN feedback alone, instead of considering the combined effect of both. In fact, this is an unexplored territory for observations due to the difficulty of separating the contribution from the two sources.In this contribution I present the discovery of a dual outflow of different species of gas in the prototypical merging galaxy NGC 6240 using HST imaging, long-slit and integral-eld spectroscopy: an AGN-driven outflow of highly-ionized gas to the northeast and a starburst-driven outflow of ionized hydrogen to the northwest. The AGN outflow extends up to 4 kpc along a position angle of 56 degrees, has a conical shape with an opening angle of 52 degrees and a maximum line-of-sight velocity of 350 km/s. The WFC3 images also reveal a bubble of Halpha emission in the northwest, which has no counterpart in [O III], consistent with a scenario in which the starburst is ionizing and driving outflowing winds which inflate the bubble at an expansion velocity of 380 km/s. Assuming a spherical geometry for the starburst-driven bubble and a conical geometry for the AGN-driven outflow, we estimate mass outflow rates of 26 Msun/yr and 62 Msun/yr, respectively. We conclude that the AGN contribution to the evolution of the merger remnant and the formation of outflowing winds is signicant in the central 5 kpc of NGC 6240.

X-Ray and Ultraviolet Properties of AGNs in Nearby Dwarf Galaxies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baldassare, Vivienne F.; Gallo, Elena; Reines, Amy E.

2017-02-10

We present new Chandra X-ray Observatory and Hubble Space Telescope observations of eight optically selected broad-line active galactic nucleus (AGN) candidates in nearby dwarf galaxies ( z < 0.055). Including archival Chandra observations of three additional sources, our sample contains all 10 galaxies from Reines et al. (2013) with both broad H α emission and narrow-line AGN ratios (six AGNs, four composites), as well as one low-metallicity dwarf galaxy with broad H α and narrow-line ratios characteristic of star formation. All 11 galaxies are detected in X-rays. Nuclear X-ray luminosities range from L {sub 0.5–7keV} ≈ 5 × 10{sup 39}more » to 1 × 10{sup 42} ergs{sup −1}. In all cases except for the star-forming galaxy, the nuclear X-ray luminosities are significantly higher than would be expected from X-ray binaries, providing strong confirmation that AGNs and composite dwarf galaxies do indeed host actively accreting black holes (BHs). Using our estimated BH masses (which range from ∼7 × 10{sup 4} to 1 × 10{sup 6} M {sub ⊙}), we find inferred Eddington fractions ranging from ∼0.1% to 50%, i.e., comparable to massive broad-line quasars at higher redshift. We use the HST imaging to determine the ratio of UV to X-ray emission for these AGNs, finding that they appear to be less X-ray luminous with respect to their UV emission than more massive quasars (i.e., α {sub OX} values an average of 0.36 lower than expected based on the relation between α {sub OX} and 2500 Å luminosity). Finally, we discuss our results in the context of different accretion models onto nuclear BHs.« less

Physical Conditions in Ultra-fast Outflows in AGN

NASA Astrophysics Data System (ADS)

Kraemer, S. B.; Tombesi, F.; Bottorff, M. C.

2018-01-01

XMM-Newton and Suzaku spectra of Active Galactic Nuclei (AGN) have revealed highly ionized gas, in the form of absorption lines from H-like and He-like Fe. Some of these absorbers, ultra-fast outflows (UFOs), have radial velocities of up to 0.25c. We have undertaken a detailed photoionization study of high-ionization Fe absorbers, both UFOs and non-UFOs, in a sample of AGN observed by XMM-Newton. We find that the heating and cooling processes in UFOs are Compton-dominated, unlike the non-UFOs. Both types are characterized by force multipliers on the order of unity, which suggest that they cannot be radiatively accelerated in sub-Eddington AGN, unless they were much less ionized at their point of origin. However, such highly ionized gas can be accelerated via a magneto-hydrodynamic (MHD) wind. We explore this possibility by applying a cold MHD flow model to the UFO in the well-studied Seyfert galaxy, NGC 4151. We find that the UFO can be accelerated along magnetic streamlines anchored in the accretion disk. In the process, we have been able to constrain the magnetic field strength and the magnetic pressure in the UFO and have determined that the system is not in magnetic/gravitational equipartition. Open questions include the variability of the UFOs and the apparent lack of non-UFOs in UFO sources.

X-ray Properties of the Central kpc of AGN and Starbursts: The Latest News from Chandra

NASA Technical Reports Server (NTRS)

Weaver, Kimberly A.; White, Nicholas E. (Technical Monitor)

2001-01-01

The X-ray properties of 15 nearby (v less than 3,000 km/s) galaxies that possess AGN (active galactic nuclei) and/or starbursts are discussed. Two-thirds have nuclear extended emission on scales from approx. 0.5 to approx. 1.5 kpc that is either clearly associated with a nuclear outflow or morphologically resembles an outflow. Galaxies that are AGN-dominated tend to have linear structures while starburst-dominated galaxies tend to have plume-like structures. Significant X-ray absorption is present in the starburst regions, indicating that a circumnuclear starburst is sufficient to block an AGN at optical wavelengths. Galaxies with starburst activity possess more X-ray point sources within their central kpc than non-starbursts. Many of these sources are more luminous than typical X-ray binaries. The Chandra results are discussed in terms of the starburst-AGN connection, a revised unified model for AGN, and possible evolutionary scenarios.

On the Star Formation-AGN Connection at zeta (is) approximately greater than 0.3

NASA Technical Reports Server (NTRS)

LaMassa, Stephanie M.; Heckman, T. M.; Ptak, Andrew; Urry, C. Megan

2013-01-01

Using the spectra of a sample of approximately 28,000 nearby obscured active galaxies from Data Release 7 of the Sloan Digital Sky Survey (SDSS), we probe the connection between active galactic nucleus (AGN) activity and star formation over a range of radial scales in the host galaxy. We use the extinction-corrected luminosity of the [O iii] 5007A line as a proxy of intrinsic AGN power and supermassive black hole (SMBH) accretion rate. The star formation rates (SFRs) are taken from the MPA-JHU value-added catalog and are measured through the 3 inch SDSS aperture. We construct matched samples of galaxies covering a range in redshifts. With increasing redshift, the projected aperture size encompasses increasing amounts of the host galaxy. This allows us to trace the radial distribution of star formation as a function of AGN luminosity. We find that the star formation becomes more centrally concentrated with increasing AGN luminosity and Eddington ratio. This implies that such circumnuclear star formation is associated with AGN activity, and that it increasingly dominates over omnipresent disk star formation at higher AGN luminosities, placing critical constraints on theoretical models that link host galaxy star formation and SMBH fueling. We parameterize this relationship and find that the star formation on radial scales (is) less than 1.7 kpc, when including a constant disk component, has a sub-linear dependence on SMBH accretion rate: SFR in proportion to solar mass(sup 0.36), suggesting that angular momentum transfer through the disk limits accretion efficiency rather than the supply from stellar mass loss.

A catalogue of faint local radio AGN and the properties of their host galaxies

NASA Astrophysics Data System (ADS)

Lofthouse, E. K.; Kaviraj, S.; Smith, D. JB; Hardcastle, M. J.

2018-05-01

We present a catalogue of local (z < 0.1) galaxies that contain faint AGN. We select these objects by identifying galaxies that exhibit a significant excess in their radio luminosities, compared to what is expected from the observed levels of star-formation activity in these systems. This is achieved by comparing the optical (spectroscopic) star formation rate (SFR) to the 1.4 GHz luminosity measured from the FIRST survey. The majority of the AGN identified in this study are fainter than those in previous work, such as in the Best and Heckman (2012) catalogue. We show that these faint AGN make a non-negligible contribution to the radio luminosity function at low luminosities (below 1022.5 W Hz-1), and host ˜13 per cent of the local radio luminosity budget. Their host galaxies are predominantly high stellar-mass systems (with a median stellar mass of 1011M⊙), are found across a range of environments (but typically in denser environments than star-forming galaxies) and have early-type morphologies. This study demonstrates a general technique to identify AGN in galaxy populations where reliable optical SFRs can be extracted using spectro-photometry and where radio data are also available so that a radio excess can be measured. Our results also demonstrate that it is unsafe to infer SFRs from radio emission alone, even if bright AGN have been excluded from a sample, since there is a significant population of faint radio AGN which may contaminate the radio-derived SFRs.

The COS revolution of AGN outflow science

NASA Astrophysics Data System (ADS)

Arav, Nahum

2016-10-01

HST/COS has opened a new discovery space for quasar outflow science. Specifically, it provides high quality FUV spectra covering the diagnostic-rich 500A-1050A rest-frame of medium redshift objects. We have published three refereed papers based on the analysis of such data that were supported by our concluded COS archive program, in which we reported: a) a new population of very high ionization outflows, b) robust cases of two-ionization-phase outflows, which are the missing link between UV AGN outflows and x-ray warm absorbers, and most importantly c) spectral diagnostics that allowed us to determine the distance of the outflows from the central source. The latter is a cardinal issue in the field as many researchers believe that most outflows are situated close to the accretion disk ( 0.01 pc) while the few reliable measurements show distances of 10-10,000 pc. Therefore, every empirical distance measurement is of importance. Our archive based publication also demonstrates that quasar outflows have sufficient energy to match theoretical predictions for AGN feedback influencing galaxy evolution.We propose to continue this successful archive program. Thus far we've analyzed about 300 COS G130M and G160M orbits of AGN observations. There are roughly 900 additional orbits that satisfy our criteria and will be available within a year. Based on our published survey, we expect that these 900 orbits will yield about 20-30 additional very-high ionization outflows and 4-6 cases of distance and kinetic luminosity determinations, all in cosmologically important luminous-quasars.

Unveiling the AGN in IC 883: discovery of a parsec-scale radio jet

NASA Astrophysics Data System (ADS)

Romero-Cañizales, C.; Alberdi, A.; Ricci, C.; Arévalo, P.; Pérez-Torres, M. Á.; Conway, J. E.; Beswick, R. J.; Bondi, M.; Muxlow, T. W. B.; Argo, M. K.; Bauer, F. E.; Efstathiou, A.; Herrero-Illana, R.; Mattila, S.; Ryder, S. D.

2017-05-01

IC 883 is a luminous infrared galaxy (LIRG) classified as a starburst-active galactic nucleus (AGN) composite. In a previous study, we detected a low-luminosity AGN (LLAGN) radio candidate. Here, we report on our radio follow-up at three frequencies that provides direct and unequivocal evidence of the AGN activity in IC 883. Our analysis of archival X-ray data, together with the detection of a transient radio source with luminosity typical of bright supernovae, gives further evidence of the ongoing star formation activity, which dominates the energetics of the system. At sub-parsec scales, the radio nucleus has a core-jet morphology with the jet being a newly ejected component showing a subluminal proper motion of 0.6-1 c. The AGN contributes less than 2 per cent of the total IR luminosity of the system. The corresponding Eddington factor is ˜10-3, suggesting this is a low-accretion rate engine, as often found in LLAGNs. However, its high bolometric luminosity (˜1044 erg s-1) agrees better with a normal AGN. This apparent discrepancy may just be an indication of the transition nature of the nucleus from a system dominated by star formation, to an AGN-dominated system. The nucleus has a strongly inverted spectrum and a turnover at ˜4.4 GHz, thus qualifying as a candidate for the least luminous (L5.0 GHz ˜ 6.3 × 1028 erg s-1 Hz-1) and one of the youngest (˜3 × 103 yr) gigahertz-peaked spectrum (GPS) sources. If the GPS origin for the IC 883 nucleus is confirmed, then advanced mergers in the LIRG category are potentially key environments to unveil the evolution of GPS sources into more powerful radio galaxies.

Formation and spatial distribution of hypervelocity stars in AGN outflows

NASA Astrophysics Data System (ADS)

Wang, Xiawei; Loeb, Abraham

2018-05-01

We study star formation within outflows driven by active galactic nuclei (AGN) as a new source of hypervelocity stars (HVSs). Recent observations revealed active star formation inside a galactic outflow at a rate of ∼ 15M⊙yr-1 . We verify that the shells swept up by an AGN outflow are capable of cooling and fragmentation into cold clumps embedded in a hot tenuous gas via thermal instabilities. We show that cold clumps of ∼ 103 M⊙ are formed within ∼ 105 yrs. As a result, stars are produced along outflow's path, endowed with the outflow speed at their formation site. These HVSs travel through the galactic halo and eventually escape into the intergalactic medium. The expected instantaneous rate of star formation inside the outflow is ∼ 4 - 5 orders of magnitude greater than the average rate associated with previously proposed mechanisms for producing HVSs, such as the Hills mechanism and three-body interaction between a star and a black hole binary. We predict the spatial distribution of HVSs formed in AGN outflows for future observational probe.

Complete Hard X-Ray Surveys, AGN Luminosity Functions and the X-Ray Background

NASA Technical Reports Server (NTRS)

Tueller, Jack

2011-01-01

AGN are believed to make up most of the Cosmic X-Ray Background (CXB) above a few keV, but this background cannot be fully resolved at energies less than 10 keV due to absorption. The Swift/BAT and INTEGRAL missions are performing the first complete hard x-ray surveys with minimal bias due to absorption. The most recent results for both missions will be presented. Although the fraction of the CXB resolved by these surveys is small, it is possible to derive unbiased number counts and luminosity functions for AGN in the local universe. The survey energy range from 15-150 keV contains the important reflection and cutoff spectral features dominate the shape of the AGN contribution to the CXB. Average spectral characteristics of survey detected AGN will be presented and compared with model distributions. The numbers of hard x-ray blazars detected in these surveys are finally sufficient to estimate this important component's contribution the cosmic background. Constraints on CXB models and their significance will be discussed.

Molecular Gas Excitation and the Evolutionary Connection Between Submillimeter Galaxies and AGN at z~2-3

NASA Astrophysics Data System (ADS)

Sharon, Chelsea; Riechers, Dominik Alexander; Carilli, Christopher; Hodge, Jacqueline; Walter, Fabian

2015-08-01

Theoretical work has suggested that active galactic nuclei (AGN) may play an important role in quenching star formation in massive galaxies. Due to sensitivity demands, direct evidence for AGN affecting the molecular ISM (the gas phase that fuels star formation) has so far been limited to detections of molecular outflows in low-redshift systems. Indirect evidence for an interplay between AGN and their host galaxies' cold gas phase may be provided by measurements of the gas excitation (and dynamics). At z~2-3, the peak epoch of star formation and AGN activity, previous observations of the CO(1-0) line revealed that submillimeter galaxies have substantial reservoirs of cold molecular gas. However, the molecular gas in AGN-host galaxies appears highly excited, potentially supporting an evolutionary connection between these two populations. We will present a new larger Karl G. Jansky Very Large Array sample that nearly doubles the number of CO(1-0) detections in z~2-3 submillimeter galaxies and AGN-host galaxies with existing CO(3-2) detections (from 13 to 23, plus four new upper limits) that allows us to better compare the low-excitation molecular gas properties of these systems and further investigate potential evidence for gas excitation due to active black holes.

Clustering of moderate luminosity X-ray-selected type 1 and type 2 AGNs at z ∼ 3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Allevato, V.; Finoguenov, A.; Civano, F.

2014-11-20

We investigate, for the first time at z ∼ 3, the clustering properties of 189 Type 1 and 157 Type 2 X-ray active galactic nuclei (AGNs) of moderate luminosity ((L {sub bol}) = 10{sup 45.3} erg s{sup –1}), with photometric or spectroscopic redshifts in the range 2.2 < z < 6.8. These samples are based on Chandra and XMM-Newton data in COSMOS. We find that Type 1 and Type 2 COSMOS AGNs at z ∼ 3 inhabit DMHs with typical mass of log M{sub h} = 12.84{sub −0.11}{sup +0.10} and 11.73{sub −0.45}{sup +0.39} h {sup –1} M {sub ☉}, respectively.more » This result requires a drop in the halo masses of Type 1 and 2 COSMOS AGNs at z ∼ 3 compared to z ≲ 2 XMM-COSMOS AGNs with similar luminosities. Additionally, we infer that unobscured COSMOS AGNs at z ∼ 3 reside in 10 times more massive halos compared to obscured COSMOS AGNs, at the 2.6σ level. This result extends to z ∼ 3 the results found in COSMOS at z ≲ 2, and rules out the picture in which obscuration is purely an orientation effect. A model which assumes that the AGNs activity is triggered by major mergers is quite successful in predicting both the low halo mass of COSMOS AGNs and the typical mass of luminous SDSS quasars at z ∼ 3, with the latter inhabiting more massive halos respect to moderate luminosity AGNs. Alternatively we can argue, at least for Type 1 COSMOS AGNs, that they are possibly representative of an early phase of fast (i.e., Eddington limited) BH growth induced by cosmic cold flows or disk instabilities. Given the moderate luminosity, these new fast growing BHs have masses of ∼10{sup 7-8} M {sub ☉} at z ∼ 3 which might evolve into ∼10{sup 8.5-9} M {sub ☉} mass BHs at z = 0. Following our clustering measurements, we argue that this fast BH growth at z ∼ 3 in AGNs with moderate luminosity occurs in DMHs with typical mass of ∼ 6× 10{sup 12} h {sup –1} M {sub ☉}.« less

Massive Molecular Outflows and Evidence for AGN Feedback from CO Observations

DTIC Science & Technology

2014-01-01

19 J. J. Thomson Avenue, Cambridge CB3 0HE, UK e-mail: c.cicone@mrao.cam.ac.uk 2 Kavli Institute for Cosmology , University of Cambridge, Madingley...about 25 arcsec from the galactic centre (corresponding to 1.6 kpc with the cosmology adopted in this paper). The CO(1–0) integrated flux in this com...power of the molecular outflow as a function of AGN luminosity. Theoretical models of AGN feedback and cosmological simulations predict a coupling effi

VizieR Online Data Catalog: 1Jy northern AGN sample (Planck+, 2016)

NASA Astrophysics Data System (ADS)

Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Aller, H. D.; Aller, M. F.; Arnaud, M.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Bartolo, N.; Battaner, E.; Benabed, K.; Benoit-Levy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bonaldi, A.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Burigana, C.; Calabrese, E.; Catalano, A.; Chiang, H. C.; Christensen, P. R.; Clements, D. L.; Colombo, L. P. L.; Couchot, F.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; De Rosa, A.; de Zotti, G.; Delabrouille, J.; Dickinson, C.; Diego, J. M.; Dole, H.; Donzelli, S.; Dore, O.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Eriksen, H. K.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A. A.; Franceschi, E.; Galeotta, S.; Galli, S.; Ganga, K.; Giard, M.; Giraud-Heraud, Y.; Gjerlow, E.; Gonzalez-Nuevo, J.; Gorski, K. M.; Gruppuso, A.; Gurwell, M. A.; Hansen, F. K.; Harrison, D. L.; Henrot-Versille, S.; Hernandez-Monteagudo, C.; Hildebrandt, S. R.; Hobson, M.; Hornstrup, A.; Hovatta, T.; Hovest, W.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Jarvela, E.; Keihanen, E.; Keskitalo, R.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lahteenmaki, A.; Lamarre, J.-M.; Lasenby, A.; Lattanzi, M.; Lawrence, C. R.; Leonardi, R.; Levrier, F.; Liguori, M.; Lilje, P. B.; Linden-Vornle, M.; Lopez-Caniego, M.; Lubin, P. M.; Macias-Perez, J. F.; Maffei, B.; Maino, D.; Mandolesi, N.; Maris, M.; Martin, P. G.; Martinez-Gonzalez, E.; Masi, S.; Matarrese, S.; Max-Moerbeck, W.; Meinhold, P. R.; Melchiorri, A.; Mennella, A.; Migliaccio, M.; Mingaliev, M.; Miville-Deschenes, M.-A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Munshi, D.; Murphy, J. A.; Nati, F.; Natoli, P.; Nieppola, E.; Noviello, F.; Novikov, D.; Novikov, I.; Pagano, L.; Pajot, F.; Paoletti, D.; Partridge, B.; Pasian, F.; Pearson, T. J.; Perdereau, O.; Perotto, L.; Pettorino, V.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Pratt, G. W.; Ramakrishnan, V.; Rastorgueva-Foi, E. A.; Readhead, A. C. S.; Reinecke, M.; Remazeilles, M.; Renault, C.; Renzi, A.; Richards, J. L.; Ristorcelli, I.; Rocha, G.; Rossetti, M.; Roudier, G.; Rubino-Martin, J. A.; Rusholme, B.; Sandri, M.; Savelainen, M.; Savini, G.; Scott, D.; Sotnikova, Y.; Stolyarov, V.; Sunyaev, R.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tammi, J.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tornikoski, M.; Tristram, M.; Tucci, M.; Turler, M.; Valenziano, L.; Valiviita, J.; Valtaoja, E.; van Tent, B.; Vielva, P.; Villa, F.; Wade, L. A.; Wehrle, A. E.; Wehus, I. K.; Yvon, D.; Zacchei, A.; Zonca, A.

2017-04-01

The complete sample presented in this paper consists of 104 northern and equatorial radio-loud AGN. It includes all AGN with declination >=-10° that have a measured average radio flux density at 37GHz exceeding 1Jy. Most of the sample sources have been monitored at Metsahovi Radio Observatory for many years, and the brightest sources have been observed for up to 30yr. (1 data file).

Ultra-fast outflows (aka UFOs) in AGNs and their relevance for feedback

NASA Astrophysics Data System (ADS)

Cappi, Massimo; Tombesi, F.; Giustini, M.; Dadina, M.; Braito, V.; Kaastra, J.; Reeves, J.; Chartas, G.; Gaspari, M.; Vignali, C.; Gofford, J.; Lanzuisi, G.

2012-09-01

During the last decade, several observational evidences have been accumulated for the existence of massive, high velocity winds/outflows (aka UFOs) in nearby AGNs and, possibly, distant quasars. I will review here such evidences, present some of the latest results in this field, and discuss the relevance of UFOs for both understanding the physics of accretion/ejection flows on supermassive black holes, and for quantifying the amount of AGN feedback.

Selective inhibition of BTK prevents murine lupus and antibody-mediated glomerulonephritis.

PubMed

Rankin, Andrew L; Seth, Nilufer; Keegan, Sean; Andreyeva, Tatyana; Cook, Tim A; Edmonds, Jason; Mathialagan, Nagappan; Benson, Micah J; Syed, Jameel; Zhan, Yutian; Benoit, Stephen E; Miyashiro, Joy S; Wood, Nancy; Mohan, Shashi; Peeva, Elena; Ramaiah, Shashi K; Messing, Dean; Homer, Bruce L; Dunussi-Joannopoulos, Kyri; Nickerson-Nutter, Cheryl L; Schnute, Mark E; Douhan, John

2013-11-01

Autoantibody production and immune complex deposition within the kidney promote renal disease in patients with lupus nephritis. Thus, therapeutics that inhibit these pathways may be efficacious in the treatment of systemic lupus erythematosus. Bruton's tyrosine kinase (BTK) is a critical signaling component of both BCR and FcR signaling. We sought to assess the efficacy of inhibiting BTK in the development of lupus-like disease, and in this article describe (R)-5-amino-1-(1-cyanopiperidin-3-yl)-3-(4-[2,4-difluorophenoxy]phenyl)-1H-pyrazole-4-carboxamide (PF-06250112), a novel highly selective and potent BTK inhibitor. We demonstrate in vitro that PF-06250112 inhibits both BCR-mediated signaling and proliferation, as well as FcR-mediated activation. To assess the therapeutic impact of BTK inhibition, we treated aged NZBxW_F1 mice with PF-06250112 and demonstrate that PF-06250112 significantly limits the spontaneous accumulation of splenic germinal center B cells and plasma cells. Correspondingly, anti-dsDNA and autoantibody levels were reduced in a dose-dependent manner. Moreover, administration of PF-06250112 prevented the development of proteinuria and improved glomerular pathology scores in all treatment groups. Strikingly, this therapeutic effect could occur with only a modest reduction observed in anti-dsDNA titers, implying a critical role for BTK signaling in disease pathogenesis beyond inhibition of autoantibody production. We subsequently demonstrate that PF-06250112 prevents proteinuria in an FcR-dependent, Ab-mediated model of glomerulonephritis. Importantly, these results highlight that BTK inhibition potently limits the development of glomerulonephritis by impacting both cell- and effector molecule-mediated pathways. These data provide support for evaluating the efficacy of BTK inhibition in systemic lupus erythematosus patients.

An X-ray/SDSS sample. II. AGN-driven outflowing gas plasma properties

NASA Astrophysics Data System (ADS)

Perna, M.; Lanzuisi, G.; Brusa, M.; Cresci, G.; Mignoli, M.

2017-10-01

Aims: Galaxy-scale outflows are currently observed in many active galactic nuclei (AGNs); however, characterisation of them in terms of their (multi-) phase nature, amount of flowing material, and effects on their host galaxy is still unresolved. In particular, ionised gas mass outflow rate and related energetics are still affected by many sources of uncertainty. In this respect, outflowing gas plasma conditions, being largely unknown, play a crucial role. Methods: We have analysed stacked spectra and sub-samples of sources with high signal-to-noise temperature- and density-sensitive emission lines to derive the plasma properties of the outflowing ionised gas component. We did this by taking advantage of the spectroscopic analysis results we obtained while studying the X-ray/SDSS sample of 563 AGNs at z < 0.8 presented in our companion paper. For these sources, we also studied in detail various diagnostic diagrams to infer information about outflowing gas ionisation mechanisms. Results: We derive, for the first time, median values for electron temperature and density of outflowing gas from medium-size samples ( 30 targets) and stacked spectra of AGNs. Evidence of shock excitation are found for outflowing gas. Conclusions: We measure electron temperatures of the order of 1.7 × 104 K and densities of 1200 cm-3 for faint and moderately luminous AGNs (intrinsic X-ray luminosity 40.5 < log (LX) < 44 in the 2-10 keV band). We note that the electron density that is usually assumed (Ne = 100 cm-3) in ejected material might result in relevant overestimates of flow mass rates and energetics and, as a consequence, of the effects of AGN-driven outflows on the host galaxy.

Subgrid Modeling of AGN-driven Turbulence in Galaxy Clusters

NASA Astrophysics Data System (ADS)

Scannapieco, Evan; Brüggen, Marcus

2008-10-01

Hot, underdense bubbles powered by active galactic nuclei (AGNs) are likely to play a key role in halting catastrophic cooling in the centers of cool-core galaxy clusters. We present three-dimensional simulations that capture the evolution of such bubbles, using an adaptive mesh hydrodynamic code, FLASH3, to which we have added a subgrid model of turbulence and mixing. While pure hydro simulations indicate that AGN bubbles are disrupted into resolution-dependent pockets of underdense gas, proper modeling of subgrid turbulence indicates that this is a poor approximation to a turbulent cascade that continues far beyond the resolution limit. Instead, Rayleigh-Taylor instabilities act to effectively mix the heated region with its surroundings, while at the same time preserving it as a coherent structure, consistent with observations. Thus, bubbles are transformed into hot clouds of mixed material as they move outward in the hydrostatic intracluster medium (ICM), much as large airbursts lead to a distinctive "mushroom cloud" structure as they rise in the hydrostatic atmosphere of Earth. Properly capturing the evolution of such clouds has important implications for many ICM properties. In particular, it significantly changes the impact of AGNs on the distribution of entropy and metals in cool-core clusters such as Perseus.

Urine epidermal growth factor, monocyte chemoattractant protein-1 or their ratio as predictors of complete remission in primary glomerulonephritis.

PubMed

Chanrat, Eakkapat; Worawichawong, Supanat; Radinahamed, Piyanuch; Sathirapongsasuti, Nuankanya; Nongnuch, Arkom; Assanatham, Montira; Udomsubpayakul, Umaporn; Kitiyakara, Chagriya

2018-04-01

The balance of several cytokines likely influences the resolution of glomerulonephritis. Monocyte chemoattractant protein-1(MCP-1) is a chemokine that promotes renal inflammation whereas epidermal growth factor (EGF) stimulates protective responses. Previously, high urine MCP-1(MCP-1) and low urine EGF (EGF) levels were found to be associated with tubulointerstitial fibrosis, but there is limited information on the value of these mediators as predictors of therapeutic responses or long term outcome in primary glomerulonephritis. To determine the performance of urine EGF, MCP-1 or their ratio at baseline as biomarkers to predict complete remission, and the relationship of these mediators with subsequent renal function 24 months later in primary glomerulonephritis. This is a prospective study of patients with biopsy-proven primary glomerulonephritis. Baseline urine samples were collected at biopsy before therapy. MCP-1 and EGF were analyzed by enzyme-linked immunosorbent assays and expressed as a ratio to urine creatinine (ng/mgCr) or as EGF/MCP-1 ratio (ng/ng). Proteinuria and estimated glomerular filtration rate (eGRF) were monitored after therapy. Complete remission (CR) was defined as proteinuria ≤ 0.3 g/gCr. Median follow-up was 20 months. Of all patients (n = 74), 38 patients (51.4%) subsequently achieved CR. Baseline urine EGF and EGF/MCP-1 levels were significantly higher in CR compared to Not CR. By contrast, MCP-1 was not different. High EGF (EGF > 75 ng/mgCr) was a significant predictor (OR 2.28) for CR by multivariate analysis after adjusting for proteinuria, blood pressure, baseline eGFR. In patients who completed 24 months follow-up (n = 43), baseline EGF correlated inversely with proteinuria and positively with eGFR at 24 months. High urine EGF level is a promising biomarker of CR. Baseline EGF levels correlated with kidney function at 2 years. EGF/MCP-1 was not superior to EGF alone. Further studies are necessary to

Galaxy Zoo: evidence for rapid, recent quenching within a population of AGN host galaxies

NASA Astrophysics Data System (ADS)

Smethurst, R. J.; Lintott, C. J.; Simmons, B. D.; Schawinski, K.; Bamford, S. P.; Cardamone, C. N.; Kruk, S. J.; Masters, K. L.; Urry, C. M.; Willett, K. W.; Wong, O. I.

2016-12-01

We present a population study of the star formation history of 1244 Type 2 active galactic nuclei (AGN) host galaxies, compared to 6107 inactive galaxies. A Bayesian method is used to determine individual galaxy star formation histories, which are then collated to visualize the distribution for quenching and quenched galaxies within each population. We find evidence for some of the Type 2 AGN host galaxies having undergone a rapid drop in their star formation rate within the last 2 Gyr. AGN feedback is therefore important at least for this population of galaxies. This result is not seen for the quenching and quenched inactive galaxies whose star formation histories are dominated by the effects of downsizing at earlier epochs, a secondary effect for the AGN host galaxies. We show that histories of rapid quenching cannot account fully for the quenching of all the star formation in a galaxy's lifetime across the population of quenched AGN host galaxies, and that histories of slower quenching, attributed to secular (non-violent) evolution, are also key in their evolution. This is in agreement with recent results showing that both merger-driven and non-merger processes are contributing to the co-evolution of galaxies and supermassive black holes. The availability of gas in the reservoirs of a galaxy, and its ability to be replenished, appear to be the key drivers behind this co-evolution.

On the mean radiative efficiency of accreting massive black holes in AGNs and QSOs

NASA Astrophysics Data System (ADS)

Zhang, XiaoXia; Lu, YouJun

2017-10-01

Radiative efficiency is an important physical parameter that describes the fraction of accretion material converted to radiative energy for accretion onto massive black holes (MBHs). With the simplest Sołtan argument, the radiative efficiency of MBHs can be estimated by matching the mass density of MBHs in the local universe to the accreted mass density by MBHs during AGN/QSO phases. In this paper, we estimate the local MBH mass density through a combination of various determinations of the correlations between the masses of MBHs and the properties of MBH host galaxies, with the distribution functions of those galaxy properties. We also estimate the total energy density radiated by AGNs and QSOs by using various AGN/QSO X-ray luminosity functions in the literature. We then obtain several hundred estimates of the mean radiative efficiency of AGNs/QSOs. Under the assumption that those estimates are independent of each other and free of systematic effects, we apply the median statistics as described by Gott et al. and find the mean radiative efficiency of AGNs/QSOs is ɛ = 0.105 -0.008 +0.006 , which is consistent with the canonical value 0.1. Considering that about 20% Compton-thick objects may be missed from current available X-ray surveys, the true mean radiative efficiency may be actually 0.12.

Extended X-ray emission in the IC 2497 - Hanny's Voorwerp system: energy injection in the gas around a fading AGN

NASA Astrophysics Data System (ADS)

Sartori, Lia F.; Schawinski, Kevin; Koss, Michael; Treister, Ezequiel; Maksym, W. Peter; Keel, William C.; Urry, C. Megan; Lintott, Chris J.; Wong, O. Ivy

2016-04-01

We present deep Chandra X-ray observations of the core of IC 2497, the galaxy associated with Hanny's Voorwerp and hosting a fading AGN. We find extended soft X-ray emission from hot gas around the low intrinsic luminosity (unobscured) AGN (Lbol ˜ 1042-1044 erg s-1). The temperature structure in the hot gas suggests the presence of a bubble or cavity around the fading AGN ({{E}}_bub ˜ 10^{54}{-}10^{55} erg). A possible scenario is that this bubble is inflated by the fading AGN, which after changing accretion state is now in a kinetic mode. Other possibilities are that the bubble has been inflated by the past luminous quasar (Lbol ˜ 1046 erg s-1), or that the temperature gradient is an indication of a shock front from a superwind driven by the AGN. We discuss the possible scenarios and the implications for the AGN-host galaxy interaction, as well as an analogy between AGN and X-ray binaries lifecycles. We conclude that the AGN could inject mechanical energy into the host galaxy at the end of its lifecycle, and thus provide a source for mechanical feedback, in a similar way as observed for X-ray binaries.

Clustering of galaxies around AGNs in the HSC Wide survey

NASA Astrophysics Data System (ADS)

Shirasaki, Yuji; Akiyama, Masayuki; Nagao, Tohru; Toba, Yoshiki; He, Wanqiu; Ohishi, Masatoshi; Mizumoto, Yoshihiko; Miyazaki, Satoshi; Nishizawa, Atsushi J.; Usuda, Tomonori

2018-01-01

We have measured the clustering of galaxies around active galactic nuclei (AGNs) for which single-epoch virial masses of the super-massive black hole (SMBH) are available to investigate the relation between the large-scale environment of AGNs and the evolution of SMBHs. The AGN samples used in this work were derived from the Sloan Digital Sky Survey (SDSS) observations and the galaxy samples were from the 240 deg2 S15b data of the Hyper Suprime-Cam Subaru Strategic Program (HSC-SSP). The investigated redshift range is 0.6-3.0, and the masses of the SMBHs lie in the range 107.5-1010 M⊙. The absolute magnitude of the galaxy samples reaches to Mλ310 ˜ -18 at rest-frame wavelength 310 nm for the low-redshift end of the samples. More than 70% of the galaxies in the analysis are blue. We found a significant dependence of the cross-correlation length on redshift, which primarily reflects the brightness-dependence of the galaxy clustering. At the lowest redshifts the cross-correlation length increases from 7 h-1 Mpc around Mλ310 = -19 mag to >10 h-1 Mpc beyond Mλ310 = -20 mag. No significant dependence of the cross-correlation length on BH mass was found for whole galaxy samples dominated by blue galaxies, while there was an indication of BH mass dependence in the cross-correlation with red galaxies. These results provides a picture of the environment of AGNs studied in this paper being enriched with blue star-forming galaxies, and a fraction of the galaxies are evolving into red galaxies along with the evolution of SMBHs in that system.

Imaging Extended Emission-Line Regions of Obscured AGN with the Subaru Hyper Suprime-Cam Survey

NASA Astrophysics Data System (ADS)

Sun, Ai-Lei; Greene, Jenny E.; Zakamska, Nadia L.; Goulding, Andy; Strauss, Michael A.; Huang, Song; Johnson, Sean; Kawaguchi, Toshihiro; Matsuoka, Yoshiki; Marsteller, Alisabeth A.; Nagao, Tohru; Toba, Yoshiki

2018-05-01

Narrow-line regions excited by active galactic nuclei (AGN) are important for studying AGN photoionization and feedback. Their strong [O III] lines can be detected with broadband images, allowing morphological studies of these systems with large-area imaging surveys. We develop a new broad-band imaging technique to reconstruct the images of the [O III] line using the Subaru Hyper Suprime-Cam (HSC) Survey aided with spectra from the Sloan Digital Sky Survey (SDSS). The technique involves a careful subtraction of the galactic continuum to isolate emission from the [O III]λ5007 and [O III]λ4959 lines. Compared to traditional targeted observations, this technique is more efficient at covering larger samples without dedicated observational resources. We apply this technique to an SDSS spectroscopically selected sample of 300 obscured AGN at redshifts 0.1 - 0.7, uncovering extended emission-line region candidates with sizes up to tens of kpc. With the largest sample of uniformly derived narrow-line region sizes, we revisit the narrow-line region size - luminosity relation. The area and radii of the [O III] emission-line regions are strongly correlated with the AGN luminosity inferred from the mid-infrared (15 μm rest-frame) with a power-law slope of 0.62^{+0.05}_{-0.06}± 0.10 (statistical and systematic errors), consistent with previous spectroscopic findings. We discuss the implications for the physics of AGN emission-line regions and future applications of this technique, which should be useful for current and next-generation imaging surveys to study AGN photoionization and feedback with large statistical samples.

Hosts and environments of low luminosity active galaxies in the local universe: The care and feeding of weak AGN

NASA Astrophysics Data System (ADS)

Parejko, John Kenneth

The observed relationship between the mass of a galaxy's supermassive black hole and the galaxy's bulge mass suggests a relationship between the growth of the galaxy and the growth of its central black hole. When these black holes grow, they release phenomenal amounts of energy into their surroundings, possibly disrupting further growth of the galaxy. The feeding (inflowing matter) and feedback (outflowing energy) of a galaxy's central black hole may be intimately related to the properties of the host's environment, on scales many orders of magnitude beyond the black hole's gravitational influence. While feeding, a massive black hole reveals itself as an Active Galactic Nucleus (AGN), but only a few percent of all galaxies show evidence of an AGN. This thesis focuses on this question: What distinguishes galaxies that are currently hosting actively accreting black holes from those that are not? We use the vast data set provided by the Sloan Digital Sky Survey (SDSS) Data Release 7 (DR7) to study the environments of a well defined sample of AGN hosts. To reduce contamination by galaxies that do not harbor actively accreting black holes, we define a clear, unambiguous sample of local AGN. Using this sample, we search for AGN in merging galaxies and measure the 2-point cross-correlation function of AGN and all galaxies to estimate the environments of AGN hosts compared to non-AGN hosts. We also describe trends in different subsamples of AGN, including luminosity and classification sub-type. Finally, we show how these techniques may be applied to future data sets such as forthcoming SDSS III data and X-ray data from the eROSITA satellite.

X-ray Evidence for Ultra-Fast Outflows in Local AGNs

NASA Astrophysics Data System (ADS)

Tombesi, F.; Cappi, M.; Sambruna, R. M.; Reeves, J. N.; Reynolds, C. S.; Braito, V.; Dadina, M.

2012-08-01

X-ray evidence for ultra-fast outflows (UFOs) has been recently reported in a number of local AGNs through the detection of blue-shifted Fe XXV/XXVI absorption lines. We present the results of a comprehensive spectral analysis of a large sample of 42 local Seyferts and 5 Broad-Line Radio Galaxies (BLRGs) observed with XMM-Newton and Suzaku. We detect UFOs in ga 40% of the sources. Their outflow velocities are in the range ˜ 0.03-0.3c, with a mean value of ˜ 0.14c. The ionization is high, in the range logℰ ˜3-6rm erg s-1 cm, and also the associated column densities are large, in the interval ˜ 1022-1024rm cm-2. Overall, these results point to the presence of highly ionized and massive outflowing material in the innermost regions of AGNs. Their variability and location on sub-pc scales favor a direct association with accretion disk winds/outflows. This also suggests that UFOs may potentially play a significant role in the AGN cosmological feedback besides jets, and their study can provide important clues on the connection between accretion disks, winds, and jets.

Necrotizing crescentic glomerulonephritis related to sarcoidosis: a case report.

PubMed

Maroz, Natallia; Field, Halle

2015-12-14

Renal injury due to sarcoidosis develops in less than a quarter of patients with this systemic disease. In most cases, granulomatous tissue alters the production of vitamin D, which leads to hypercalciuria, nephrocalcinosis, and nephrolithiasis. Granulomatous interstitial nephritis is another well-recognized pathological process associated with sarcoidosis. However, a glomerular pathology is very rarely noted, and only a few cases are reported to have cellular crescentic glomerulonephritis. We describe the case of a 26-year-old African American woman with systemic sarcoidosis, with a unique constellation of renal lesions, including noncaseating epithelioid granulomatous necrotizing interstitial nephritis, cellular crescent formation, and necrotizing vasculitis. Immunosuppressive therapy was helpful for alleviating her nephrotic syndrome and maintaining the stability of her renal function over a 30-month period. Glomerular involvement of sarcoidosis needs to be considered in the differential diagnosis in cases of rapidly progressive glomerular nephritis.

DISENTANGLING AGN AND STAR FORMATION ACTIVITY AT HIGH REDSHIFT USING HUBBLE SPACE TELESCOPE GRISM SPECTROSCOPY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bridge, Joanna S.; Zeimann, Gregory R.; Trump, Jonathan R.

2016-08-01

Differentiating between active galactic nucleus (AGN) activity and star formation in z ∼ 2 galaxies is difficult because traditional methods, such as line-ratio diagnostics, change with redshift, while multi-wavelength methods (X-ray, radio, IR) are sensitive to only the brightest AGNs. We have developed a new method for spatially resolving emission lines using the Hubble Space Telescope /Wide Field Camera 3 G141 grism spectra and quantifying AGN activity through the spatial gradient of the [O iii]/H β line ratio. Through detailed simulations, we show that our novel line-ratio gradient approach identifies ∼40% more low-mass and obscured AGNs than obtained by classicalmore » methods. Based on our simulations, we developed a relationship that maps the stellar mass, star formation rate, and measured [O iii]/H β gradient to the AGN Eddington ratio. We apply our technique to previously studied stacked samples of galaxies at z ∼ 2 and find that our results are consistent with these studies. This gradient method will also be able to inform other areas of galaxy evolution science, such as inside-out quenching and metallicity gradients, and will be widely applicable to future spatially resolved James Webb Space Telescope data.« less

Unveiling slim accretion disc in AGN through X-ray and Infrared observations

NASA Astrophysics Data System (ADS)

Castelló-Mor, Núria; Kaspi, Shai; Netzer, Hagai; Du, Pu; Hu, Chen; Ho, Luis C.; Bai, Jin-Ming; Bian, Wei-Hao; Yuan, Ye-Fei; Wang, Jian-Min

2017-05-01

In this work, which is a continuation of Castelló-Mor et al., we present new X-ray and infrared (IR) data for a sample of active galactic nuclei (AGN) covering a wide range in Eddington ratio over a small luminosity range. In particular, we rigorously explore the dependence of the optical-to-X-ray spectral index αOX and the IR-to-optical spectral index on the dimensionless accretion rate, \\dot{M} = \\dot{m}/η, where \\dot{m} = LAGN/LEdd and η is the mass-to-radiation conversion efficiency, in low- and high-accretion rate sources. We find that the spectral energy distribution (SED) of the faster accreting sources is surprisingly similar to those from the comparison sample of sources with lower accretion rate. In particular: (I) The optical-to-UV AGN SED of slow and fast accreting AGN can be fitted with thin accretion disc (AD) models. (II) The value of αOX is very similar in slow and fast accreting systems up to a dimensionless accretion rate \\dot{M}c ˜ 10. We only find a correlation between αOX and \\dot{M} for sources with \\dot{M} > \\dot{M}c. In such cases, the faster accreting sources appear to have systematically larger αOX values. (III) We also find that the torus in the faster accreting systems seems to be less efficient in reprocessing the primary AGN radiation having lower IR-to-optical spectral slopes. These findings, failing to recover the predicted differences between the SEDs of slim and thin ADs within the observed spectral window, suggest that additional physical processes or very special geometry act to reduce the extreme-UV radiation in fast accreting AGN. This may be related to photon trapping, strong winds and perhaps other yet unknown physical processes.

The Effect of AGN Heating on the Low-redshift Lyα Forest

NASA Astrophysics Data System (ADS)

Gurvich, Alex; Burkhart, Blakesley; Bird, Simeon

2017-02-01

We investigate the effects of AGN heating and the ultraviolet background on the low-redshift Lyα forest column density distribution (CDD) using the Illustris simulation. We show that Illustris reproduces observations at z = 0.1 in the column density range {10}12.5{--}{10}13.5 cm-2, relevant for the “photon underproduction crisis.” We attribute this to the inclusion of AGN feedback, which changes the gas distribution so as to mimic the effect of extra photons, as well as the use of the Faucher-Giguère ultraviolet background, which is more ionizing at z = 0.1 than the Haardt & Madau background previously considered. We show that the difference between simulations run with smoothed particle hydrodynamics and simulations using a moving mesh is small in this column density range but can be more significant at larger column densities. We further consider the effect of supernova feedback, Voigt profile fitting, and finite resolution, all of which we show to have little influence on the CDD. Finally, we identify a discrepancy between our simulations and observations at column densities {10}14{--}{10}16 cm-2, where Illustris produces too few absorbers, which suggests the AGN feedback model should be further refined. Since the “photon underproduction crisis” primarily affects lower column density systems, we conclude that AGN feedback and standard ionizing background models can resolve the crisis.

The NuSTAR Serendipitous Survey: Hunting for the Most Extreme Obscured AGN at >10 keV

NASA Astrophysics Data System (ADS)

Lansbury, G. B.; Alexander, D. M.; Aird, J.; Gandhi, P.; Stern, D.; Koss, M.; Lamperti, I.; Ajello, M.; Annuar, A.; Assef, R. J.; Ballantyne, D. R.; Baloković, M.; Bauer, F. E.; Brandt, W. N.; Brightman, M.; Chen, C.-T. J.; Civano, F.; Comastri, A.; Del Moro, A.; Fuentes, C.; Harrison, F. A.; Marchesi, S.; Masini, A.; Mullaney, J. R.; Ricci, C.; Saez, C.; Tomsick, J. A.; Treister, E.; Walton, D. J.; Zappacosta, L.

2017-09-01

We identify sources with extremely hard X-ray spectra (I.e., with photon indices of {{Γ }}≲ 0.6) in the 13 deg2 NuSTAR serendipitous survey, to search for the most highly obscured active galactic nuclei (AGNs) detected at > 10 {keV}. Eight extreme NuSTAR sources are identified, and we use the NuSTAR data in combination with lower-energy X-ray observations (from Chandra, Swift XRT, and XMM-Newton) to characterize the broadband (0.5-24 keV) X-ray spectra. We find that all of the extreme sources are highly obscured AGNs, including three robust Compton-thick (CT; {N}{{H}}> 1.5× {10}24 cm-2) AGNs at low redshift (z< 0.1) and a likely CT AGN at higher redshift (z = 0.16). Most of the extreme sources would not have been identified as highly obscured based on the low-energy (< 10 keV) X-ray coverage alone. The multiwavelength properties (e.g., optical spectra and X-ray-mid-IR luminosity ratios) provide further support for the eight sources being significantly obscured. Correcting for absorption, the intrinsic rest-frame 10-40 keV luminosities of the extreme sources cover a broad range, from ≈ 5× {10}42 to 1045 erg s-1. The estimated number counts of CT AGNs in the NuSTAR serendipitous survey are in broad agreement with model expectations based on previous X-ray surveys, except for the lowest redshifts (z< 0.07), where we measure a high CT fraction of {f}{CT}{obs}={30}-12+16 % . For the small sample of CT AGNs, we find a high fraction of galaxy major mergers (50% ± 33%) compared to control samples of “normal” AGNs.

The AGN activity in a sample of IR Luminous Major Mergers

NASA Astrophysics Data System (ADS)

Loiseau, N.; de Rosa, A.; Bianchi, S.; Bogdanovich, T.

2017-10-01

As part of our study of the nuclear activity in a sample of 70 IR luminous major mergers we obtained XMM-Newton data of 4 more pairs of these galaxies. This is part of our multiwavelength study of the nuclear activity in mergers and groups of galaxies (MAGNA collaboration). Our purpose is to understand in which cases one or both of the galaxies of the major merger would have a massive black hole, and if the interaction stage, or the mass/type of the galaxies have role in the enhanced AGN and/or Starburst activity. X-rays can be the best tool to detect hidden AGN. At present very few mergers of AGN simultaneously active have been detected, most of them serendipitously. We present here the X-ray data of these 4 pairs, which have been selected using their WISE colors as a diagnostic tool. We compare the results for these 8 galaxies with the data of the 33 merging galaxies of this sample previously detected with XMM-Newton or Chandra.

A gas-rich AGN near the centre of a galaxy cluster at z ~ 1.4

NASA Astrophysics Data System (ADS)

Casasola, V.; Magrini, L.; Combes, F.; Mignano, A.; Sani, E.; Paladino, R.; Fontani, F.

2013-10-01

Context. The formation of the first virialized structures in overdensities dates back to ~9 Gyr ago, i.e. in the redshift range z ~ 1.4-1.6. Some models of structure formation predict that the star formation activity in clusters was high at that epoch, implying large reservoirs of cold molecular gas. Aims: Aiming at finding a trace of this expected high molecular gas content in primeval clusters, we searched for the 12CO(2-1) line emission in the most luminous active galactic nucleus (AGN) of the cluster around the radio galaxy 7C 1756+6520 at z ~ 1.4, one of the farthest spectroscopic confirmed clusters. This AGN, called AGN.1317, is located in the neighbourhood of the central radio galaxy at a projected distance of ~780 kpc. Methods: The IRAM Plateau de Bure Interferometer was used to investigate the molecular gas quantity in AGN.1317, observing the 12CO(2-1) emission line. Results: We detect CO emission in an AGN belonging to a galaxy cluster at z ~ 1.4. We measured a molecular gas mass of 1.1 × 1010M⊙, comparable to that found in submillimeter galaxies. In optical images, AGN.1317 does not seem to be part of a galaxy interaction or merger. We also derived the nearly instantaneous star formation rate (SFR) from Hα flux obtaining a SFR ~ 65 M⊙ yr-1. This suggests that AGN.1317 is actively forming stars and will exhaust its reservoir of cold gas in ~0.2-1.0 Gyr. Based on observations carried out with the IRAM Plateau de Bure Interferometer. IRAM is supported by INSU/CNRS (France), MPG (Germany), and IGN (Spain).Reduced IRAM data is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/558/A60

Bartonella endocarditis with glomerulonephritis in a patient with complete transposition of the great arteries.

PubMed

Hashemi, Helen; Endicott-Yazdani, Tiana R; Oguayo, Christopher; Harmon, David M; Tran, Tuan; Tsai-Nguyen, Ginger; Benavides, Raul; Spak, Cedric W; Nguyen, Hoang-Lan

2018-01-01

We describe a patient with history of dextro-transposition of the great vessels, ventricular septal defect, and pulmonary valve replacement who presented with fatigue, prolonged fever, and leg edema. He was found to have kidney injury, pancytopenia, and liver congestion. Echocardiogram revealed thickened leaflets with prolapsing vegetation on the pulmonary valve. Given the negative blood cultures, high Bartonella henselae immunogobulin G titer (≥1:1024) and positive immunoglobulin M titer (≥1:20), he was diagnosed with Bartonella endocarditis complicated with glomerulonephritis.

Hurricane Agnes rainfall and floods, June-July 1972

USGS Publications Warehouse

Bailey, James F.; Patterson, James Lee; Paulhus, Joseph Louis Hornore

1975-01-01

Hurricane Agnes originated in the Caribbean Sea region in mid-June. Circulation barely reached hurricane intensity for a brief period in the Gulf of Mexico. The storm crossed the Florida Panhandle coastline on June 19, 1972, and followed an unusually extended overland trajectory combining with an extratropical system to bring very heavy rain from the Carolinas northward to New York. This torrential rain followed the abnormally wet May weather in the Middle Atlantic States and set the stage for the subsequent major flooding. The record-breaking floods occurred in the Middle Atlantic States in late June and early July 1972. Many streams in the affected area experienced peak discharges several times the previous maxima of record. Estimated recurrence intervals of peak flows at many gaging stations on major rivers and their tributaries exceeded 100 years. The suspended-sediment concentration and load of most flooded streams were also unusually high. The widespread flooding from this storm caused Agnes to be called the most destructive hurricane in United States history, claiming 117 lives and causing damage estimated at $3.1 billion in 12 States. Damage was particularly high in New York, Pennsylvania, Maryland, and Virginia. The detailed life history of Hurricane Agnes, including the tropical depression and tropical storm stages, is traced. Associated rainfalls are analyzed and compared with climatologic recurrence values. These are followed by a detailed description of the flood and streamflows of each affected basin. A summary of peak stages and discharges and comparison data for previous floods at 989 stations are presented. Deaths and flood damage estimates are compiled.

The mm-wave compact component of AGN

NASA Astrophysics Data System (ADS)

Behar, Ehud; Vogel, Stuart; Baldi, Ranieri D.; Smith, Krista L.; Mushotzky, Richard F.

2018-05-01

mm-wave emission from Active Galactic Nuclei (AGN) may hold the key to understanding the physical origin of their radio cores. The correlation between radio/mm and X-ray luminosity may suggest a similar physical origin of the two sources. Since synchrotron self absorption decreases with frequency, mm-waves probe smaller length scales than cm-waves. We report on 100 GHz (3 mm) observations with CARMA of 26 AGNs selected from the hard X-ray Swift/BAT survey. 20/26 targets were detected at 100 GHz down to the 1 mJy (3σ) sensitivity, which corresponds to optically thick synchrotron source sizes of 10-4 - 10-3 pc. Most sources show a 100 GHz flux excess with respect to the spectral slope extrapolated from low frequencies. This mm spectral component likely originates from smaller scales than the few-GHz emission. The measured mm sources lie roughly around the Lmm (100 GHz) ˜10-4LX (2-10 keV) relation, similar to a few previously published X-ray selected sources, and hinting perhaps at a common coronal origin.

Shedding New Light on the Innermost Regions of AGN with XMM, Suzaku and NuSTAR

NASA Astrophysics Data System (ADS)

Brenneman, Laura

We request funding for two years ($257,041 in total) in support of accepted XMM- Newton and Suzaku observations of six bright, nearby active galactic nuclei (AGN): MCG-6-30-15, Ark 120, SWIFT J2127.4+5654, 3C120, NGC 4151 and IC 4329A. The first four of these AGN are to be observed simultaneously with XMM and NuSTAR during XMM's AO11 cycle, while the last two AGN will be studied simultaneously with Suzaku and NuSTAR during Suzaku's AO7 cycle. All six AGN observations were approved with priority A, and our observing campaign totals 1.14 Msec of exposure time. The XMM and Suzaku programs share four common goals: (1) to measure the angular momenta of the supermassive black holes (SMBHs) at the hearts of these active galaxies, (2) to accurately characterize the physical properties of the poorly understood inner accretion disk/corona region in these AGN, and (3) to identify the driver(s) of the spectral variability across multiple physical timescales in these systems, and (4) to examine correlations that exist between the various physical properties of these SMBHs and their surroundings. These three science goals address a critical component of NASA's Physics of the Cosmos mission: "the behavior of matter and energy in extreme environments." The high prioritization and long exposures of our awarded XMM and Suzaku observations underscore the scientific merit of these goals, as judged by the high-energy astronomy community. Our observing campaign will yield simultaneous broad-band X-ray spectra (0.2-80 keV) of these AGN with the best signal-to-noise and spectral resolution ever obtained across this energy range, guaranteeing new insights into the physics at work in the innermost regions around SMBHs. Using a combination of timing analysis and detailed spectral modeling, we will achieve the first truly accurate understanding of the nature of the X-ray continuum in AGN. The low-background, high-energy data from NuSTAR in tandem with the sensitivity at lower energies from

Confinement and diffusion time-scales of CR hadrons in AGN-inflated bubbles

NASA Astrophysics Data System (ADS)

Prokhorov, D. A.; Churazov, E. M.

2017-09-01

While rich clusters are powerful sources of X-rays, γ-ray emission from these large cosmic structures has not been detected yet. X-ray radiative energy losses in the central regions of relaxed galaxy clusters are so strong that one needs to consider special sources of energy, likely active galactic nucleus (AGN) feedback, to suppress catastrophic cooling of the gas. We consider a model of AGN feedback that postulates that the AGN supplies the energy to the gas by inflating bubbles of relativistic plasma, whose energy content is dominated by cosmic-ray (CR) hadrons. If most of these hadrons can quickly escape the bubbles, then collisions of CRs with thermal protons in the intracluster medium (ICM) should lead to strong γ-ray emission, unless fast diffusion of CRs removes them from the cluster. Therefore, the lack of detections with modern γ-ray telescopes sets limits on the confinement time of CR hadrons in bubbles and CR diffusive propagation in the ICM.

An X-ray/SDSS sample. I. Multi-phase outflow incidence and dependence on AGN luminosity

NASA Astrophysics Data System (ADS)

Perna, M.; Lanzuisi, G.; Brusa, M.; Mignoli, M.; Cresci, G.

2017-07-01

Aims: The connection between the growth of super-massive black holes (SMBHs) and the evolution of their host galaxies is nowadays well established, although the underlying mechanisms explaining their mutual relations are still debated. Multi-phase fast, massive outflows have been postulated to play a crucial role in this process. The aim of this work is to constrain the nature and the fraction of outflowing gas in active galactic nuclei (AGNs) as well as the nuclear conditions possibly at the origin of such phenomena. Methods: We present a large spectroscopic sample of X-ray detected SDSS AGNs at z< 0.8 with a high signal-to-noise ratio in the [O III]λ5007 line to unveil the faint wings of the emission profile associated with AGN-driven outflows. We used X-ray and optical flux ratio diagnostics to select the sample. We derived physical and kinematic characterization by re-analysing optical (and X-ray) spectra. Results: We derive the incidence of ionized ( 40%) and atomic (<1%) outflows covering a wide range of AGN bolometric luminosity from 1042 to 1046 erg/s. We also derive bolometric luminosities and X-ray bolometric corrections to test whether the presence of outflows is associated with an X-ray loudness, as suggested by our recent results obtained by studying high-z QSOs. Conclusions: We study the relations between the outflow velocity inferred from [O III] kinematic analysis and different AGN power tracers, such as black hole mass (MBH), [O III], and X-ray luminosity. We show a well-defined positive trend between outflow velocity and LX, for the first time, over a range of 5 order of magnitudes. Overall, we find that in the QSO-luminosity regime and at MBH> 108M⊙ the fraction of AGNs with outflows becomes >50%. Finally, we discuss our results about X-ray bolometric corrections and outflow incidence in cold and ionized phases in the context of an evolutionary sequence allowing two distinct stages for the feedback phase: first, an initial stage characterized

VizieR Online Data Catalog: Variability-selected AGN in Chandra DFS (Trevese+, 2008)

NASA Astrophysics Data System (ADS)

Trevese, D.; Boutsia, K.; Vagnetti, F.; Cappellaro, E.; Puccetti, S.

2008-11-01

Variability is a property shared by virtually all active galactic nuclei (AGNs), and was adopted as a criterion for their selection using data from multi epoch surveys. Low Luminosity AGNs (LLAGNs) are contaminated by the light of their host galaxies, and cannot therefore be detected by the usual colour techniques. For this reason, their evolution in cosmic time is poorly known. Consistency with the evolution derived from X-ray detected samples has not been clearly established so far, also because the low luminosity population consists of a mixture of different object types. LLAGNs can be detected by the nuclear optical variability of extended objects. Several variability surveys have been, or are being, conducted for the detection of supernovae (SNe). We propose to re-analyse these SNe data using a variability criterion optimised for AGN detection, to select a new AGN sample and study its properties. We analysed images acquired with the wide field imager at the 2.2m ESO/MPI telescope, in the framework of the STRESS supernova survey. We selected the AXAF field centred on the Chandra Deep Field South where, besides the deep X-ray survey, various optical data exist, originating in the EIS and COMBO-17 photometric surveys and the spectroscopic database of GOODS. (1 data file).

CHANDRA X-RAY AND HUBBLE SPACE TELESCOPE IMAGING OF OPTICALLY SELECTED KILOPARSEC-SCALE BINARY ACTIVE GALACTIC NUCLEI. II. HOST GALAXY MORPHOLOGY AND AGN ACTIVITY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shangguan, Jinyi; Ho, Luis C.; Liu, Xin

Binary active galactic nuclei (AGNs) provide clues to how gas-rich mergers trigger and fuel AGNs and how supermassive black hole (SMBH) pairs evolve in a gas-rich environment. While significant effort has been invested in their identification, the detailed properties of binary AGNs and their host galaxies are still poorly constrained. In a companion paper, we examined the nature of ionizing sources in the double nuclei of four kiloparsec-scale binary AGNs with redshifts between 0.1 and 0.2. Here, we present their host galaxy morphology based on F336W ( U -band) and F105W ( Y -band) images taken by the Wide Fieldmore » Camera 3 on board the Hubble Space Telescope . Our targets have double-peaked narrow emission lines and were confirmed to host binary AGNs with follow-up observations. We find that kiloparsec-scale binary AGNs occur in galaxy mergers with diverse morphological types. There are three major mergers with intermediate morphologies and a minor merger with a dominant disk component. We estimate the masses of the SMBHs from their host bulge stellar masses and obtain Eddington ratios for each AGN. Compared with a representative control sample drawn at the same redshift and stellar mass, the AGN luminosities and Eddington ratios of our binary AGNs are similar to those of single AGNs. The U − Y color maps indicate that clumpy star-forming regions could significantly affect the X-ray detection of binary AGNs, e.g., the hardness ratio. Considering the weak X-ray emission in AGNs triggered in merger systems, we suggest that samples of X-ray-selected AGNs may be biased against gas-rich mergers.« less

Radio-loud AGN through the eyes of 3XMM, WISE and FIRST/NVSS

NASA Astrophysics Data System (ADS)

Mingo, B.

2014-07-01

We present the results from a new radio-loud AGN sample, obtained through the cross-correlation between the 3XMM, WISE and FIRST/NVSS catalogues. The radio selection allows us to eliminate the restrictions traditionally associated with mid-IR and X-ray sample selections, and to explore the population of lower luminosity AGN, in which the host galaxy contribution is substantial. We investigate the correlations between radio, mid-IR and X-ray emission associated to both stellar and AGN activity, and whether they can be disentangled. This work has been carried out as part of the ARCHES project. ARCHES (Astronomical Resource Cross-matching for High Energy Studies), funded within the EU/FP7-Cooperation Space framework, is a project which aims to produce well-characterised multi-wavelength data for large samples of sources drawn from the 3XMM serendipitous source catalogue.

NoSOCS in SDSS - VI. The environmental dependence of AGN in clusters and field in the local Universe

NASA Astrophysics Data System (ADS)

Lopes, P. A. A.; Ribeiro, A. L. B.; Rembold, S. B.

2017-11-01

We investigated the variation in the fraction of optical active galactic nuclei (AGNs) hosts with stellar mass, as well as their local and global environments. Our sample is composed of cluster members and field galaxies at z ≤ 0.1 and we consider only strong AGN. We find a strong variation in the AGN fraction (FAGN) with stellar mass. The field population comprises a higher AGN fraction compared to the global cluster population, especially for objects with log M* > 10.6. Hence, we restricted our analysis to more massive objects. We detected a smooth variation in the FAGN with local stellar mass density for cluster objects, reaching a plateau in the field environment. As a function of cluster-centric distance we verify that FAGN is roughly constant for R > R200, but show a steep decline inwards. We have also verified the dependence of the AGN population on cluster velocity dispersion, finding a constant behaviour for low mass systems (σP ≲ 650-700 km s-1). However, there is a strong decline in FAGN for higher mass clusters (>700 km s-1). When comparing the FAGN in clusters with or without substructure, we only find different results for objects at large radii (R > R200), in the sense that clusters with substructure present some excess in the AGN fraction. Finally, we have found that the phase-space distribution of AGN cluster members is significantly different than other populations. Due to the environmental dependence of FAGN and their phase-space distribution, we interpret AGN to be the result of galaxy interactions, favoured in environments where the relative velocities are low, typical of the field, low mass groups or cluster outskirts.

Streptococcal acute pharyngitis.

PubMed

Anjos, Lais Martins Moreira; Marcondes, Mariana Barros; Lima, Mariana Ferreira; Mondelli, Alessandro Lia; Okoshi, Marina Politi

2014-07-01

Acute pharyngitis/tonsillitis, which is characterized by inflammation of the posterior pharynx and tonsils, is a common disease. Several viruses and bacteria can cause acute pharyngitis; however, Streptococcus pyogenes (also known as Lancefield group A β-hemolytic streptococci) is the only agent that requires an etiologic diagnosis and specific treatment. S. pyogenes is of major clinical importance because it can trigger post-infection systemic complications, acute rheumatic fever, and post-streptococcal glomerulonephritis. Symptom onset in streptococcal infection is usually abrupt and includes intense sore throat, fever, chills, malaise, headache, tender enlarged anterior cervical lymph nodes, and pharyngeal or tonsillar exudate. Cough, coryza, conjunctivitis, and diarrhea are uncommon, and their presence suggests a viral cause. A diagnosis of pharyngitis is supported by the patient's history and by the physical examination. Throat culture is the gold standard for diagnosing streptococcus pharyngitis. However, it has been underused in public health services because of its low availability and because of the 1- to 2-day delay in obtaining results. Rapid antigen detection tests have been used to detect S. pyogenes directly from throat swabs within minutes. Clinical scoring systems have been developed to predict the risk of S. pyogenes infection. The most commonly used scoring system is the modified Centor score. Acute S. pyogenes pharyngitis is often a self-limiting disease. Penicillins are the first-choice treatment. For patients with penicillin allergy, cephalosporins can be an acceptable alternative, although primary hypersensitivity to cephalosporins can occur. Another drug option is the macrolides. Future perspectives to prevent streptococcal pharyngitis and post-infection systemic complications include the development of an anti-Streptococcus pyogenes vaccine.

Mabel Agnes Elliott, We Hardly Knew You

ERIC Educational Resources Information Center

McGonigal, Kathryn; Galliher, John F.

2008-01-01

Sociologist Mabel Agnes Elliott was elected the fourth president of the Society for the Study of Social Problems in 1956-1957 and was the first woman to hold this position. She was an anti-war activist, a feminist and a creative and diligent writer. Yet she experienced many challenges. The Federal Bureau of Investigation kept an active file on…

Simulations of AGN jets: magnetic kink instability versus conical shocks

NASA Astrophysics Data System (ADS)

Barniol Duran, Rodolfo; Tchekhovskoy, Alexander; Giannios, Dimitrios

2017-08-01

Relativistic jets in active galactic nuclei (AGN) convert as much as half of their energy into radiation. To explore the poorly understood processes that are responsible for this conversion, we carry out fully 3D magnetohydrodynamic (MHD) simulations of relativistic magnetized jets. Unlike the standard approach of injecting the jets at large radii, our simulated jets self-consistently form at the source and propagate and accelerate outwards for several orders of magnitude in distance before they interact with the ambient medium. We find that this interaction can trigger strong energy dissipation of two kinds inside the jets, depending on the properties of the ambient medium. Those jets that form in a new outburst and drill a fresh hole through the ambient medium fall victim to a 3D magnetic kink instability and dissipate their energy primarily through magnetic reconnection in the current sheets formed by the instability. On the other hand, those jets that form during repeated cycles of AGN activity and escape through a pre-existing hole in the ambient medium maintain their stability and dissipate their energy primarily at MHD recollimation shocks. In both cases, the dissipation region can be associated with a change in the density profile of the ambient gas. The Bondi radius in AGN jets serves as such a location.

The Keck/OSIRIS Nearby AGN Survey (KONA). I. The Nuclear K-band Properties of Nearby AGN

NASA Astrophysics Data System (ADS)

Müller-Sánchez, F.; Hicks, E. K. S.; Malkan, M.; Davies, R.; Yu, P. C.; Shaver, S.; Davis, B.

2018-05-01

We introduce the Keck OSIRIS Nearby AGN survey (KONA), a new adaptive optics-assisted integral-field spectroscopic survey of Seyfert galaxies. KONA permits at ∼0.″1 resolution a detailed study of the nuclear kinematic structure of gas and stars in a representative sample of 40 local bona fide active galactic nucleus (AGN). KONA seeks to characterize the physical processes responsible for the coevolution of supermassive black holes and galaxies, principally inflows and outflows. With these IFU data of the nuclear regions of 40 Seyfert galaxies, the KONA survey will be able to study, for the first time, a number of key topics with meaningful statistics. In this paper we study the nuclear K-band properties of nearby AGN. We find that the K-band (2.1 μm) luminosities of the compact Seyfert 1 nuclei are correlated with the hard X-ray luminosities, implying a non-stellar origin for the majority of the continuum emission. The best-fit correlation is log L K = 0.9log L 2–10 keV + 4 over three orders of magnitude in both K-band and X-ray luminosities. We find no strong correlation between 2.1 μm luminosity and hard X-ray luminosity for the Seyfert 2 galaxies. The spatial extent and spectral slope of the Seyfert 2 galaxies indicate the presence of nuclear star formation and attenuating material (gas and dust), which in some cases is compact and in some galaxies extended. We detect coronal-line emission in 36 galaxies and for the first time in 5 galaxies. Finally, we find 4/20 galaxies that are usually classified as Seyfert 2 based on their optical spectra exhibit a broad component of Brγ emission, and one galaxy (NGC 7465) shows evidence of a double nucleus. Based on observations at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration. The observatory was made possible by the generous financial support of the W. M

Environment Study of AGNs at z = 0.3 to 3.0 Using the Japanese Virtual Observatory

NASA Astrophysics Data System (ADS)

Shirasaki, Y.; Ohishi, M.; Mizumoto, Y.; Takata, T.; Tanaka, M.; Yasuda, N.

2010-12-01

We present a science use case of Virtual Observatory, which was achieved to examine an environment of AGN up to redshift of 3.0. We used the Japanese Virtual Observatory (JVO) to obtain Subaru Suprime-Cam images around known AGNs. According to the hierarchical galaxy formation model, AGNs are expected to be found in an environment of higher galaxy density than that of typical galaxies. The current observations, however, indicate that AGNs do not reside in a particularly high density environment. We investigated ˜1000 AGNs, which is about ten times larger samples than the other studies covering the redshifts larger than 0.6. We successfully found significant excess of galaxies around AGNs at redshifts of 0.3 to 1.8. If this work was done in a classical manner, that is, raw data were retrieved from the archive through a form-based web interface in an interactive way, and the data were reduced on a low performance computer, it might take several years to finish it. Since the Virtual Observatory system is accessible through a standard interface, it is easy to query and retrieve data in an automatic way. We constructed a pipeline for retrieving the data and calculating the galaxy number density around a given coordinate. This procedure was executed in parallel on ˜10 quad core PCs, and it took only one day for obtaining the final result. Our result implies that the Virtual Observatory can be a powerful tool to do an astronomical research based on large amount of data.

Pinpointing the base of the AGN jets through general relativistic X-ray reverberation studies

NASA Astrophysics Data System (ADS)

Emmanoulopoulos, D.

2015-03-01

Many theoretical models of Active Galactic Nuclei (AGN) predict that the X-ray corona, lying above the black hole, constitutes the base of the X-ray jet. Thus, by studying the exact geometry of the close black hole environment, we can pinpoint the launching site of the jet. Detection of negative X-ray reverberation time delays (i.e. soft band X-ray variations lagging behind the corresponding hard band X-ray variations) can yield significant information about the geometrical properties of the AGN, such as the location of the X-ray source, as well as the physical properties of the the black hole, such as its mass and spin. In the frame-work of the lamp-post geometry, I present the first systematic X-ray time-lag modelling results of an ensemble of 12 AGN, using a fully general relativistic (GR) ray tracing approach for the estimation of the systems' response functions. By combing these state-of-the art GR response models with statistically innovative fitting routines, I derive the geometrical layout of the close BH environment for each source, unveiling the position of the AGN jet-base.

Bartonella endocarditis with glomerulonephritis in a patient with complete transposition of the great arteries

PubMed Central

Hashemi, Helen; Endicott-Yazdani, Tiana R.; Oguayo, Christopher; Harmon, David M.; Tran, Tuan; Tsai-Nguyen, Ginger; Benavides, Raul; Spak, Cedric W.; Nguyen, Hoang-Lan

2018-01-01

ABSTRACT We describe a patient with history of dextro-transposition of the great vessels, ventricular septal defect, and pulmonary valve replacement who presented with fatigue, prolonged fever, and leg edema. He was found to have kidney injury, pancytopenia, and liver congestion. Echocardiogram revealed thickened leaflets with prolapsing vegetation on the pulmonary valve. Given the negative blood cultures, high Bartonella henselae immunogobulin G titer (≥1:1024) and positive immunoglobulin M titer (≥1:20), he was diagnosed with Bartonella endocarditis complicated with glomerulonephritis. PMID:29686571

Proliferative glomerulonephritis with monoclonal IgG deposits in two kidney allografts successfully treated with rituximab.

PubMed

Merhi, Basma; Patel, Nikunjkuma; Bayliss, George; Henriksen, Kammi J; Gohh, Reginald

2017-06-01

Proliferative glomerulonephritis with monoclonal immunoglobulin G deposit (PGNMID), a recently described pathologic entity in native kidneys, has been recognized in kidney transplant patients, where it can present as either recurrent or de novo disease. There is no definitive treatment to date, in either population. Here, we present two cases of PGNMID in kidney allografts that illustrate the challenges of diagnostic approach and highlight the allograft outcome after treatment with rituximab as a potential treatment of this condition.

Radio continuum properties of luminous infrared galaxies. Identifying the presence of an AGN in the radio

NASA Astrophysics Data System (ADS)

Vardoulaki, E.; Charmandaris, V.; Murphy, E. J.; Diaz-Santos, T.; Armus, L.; Evans, A. S.; Mazzarella, J. M.; Privon, G. C.; Stierwalt, S.; Barcos-Muñoz, L.

2015-02-01

Context. Luminous infrared galaxies (LIRGs) are systems enshrouded in dust, which absorbs most of their optical/UV emission and radiates it again in the mid- and far-infrared. Radio observations are largely unaffected by dust obscuration, enabling us to study the central regions of LIRGs in an unbiased manner. Aims: The main goal of this project is to examine how the radio properties of local LIRGs relate to their infrared spectral characteristics. Here we present an analysis of the radio continuum properties of a subset of the Great Observatories All-sky LIRG Survey (GOALS), which consists of 202 nearby systems (z< 0.088). Our radio sample consists of 35 systems, containing 46 individual galaxies, that were observed at both 1.49 and 8.44 GHz with the VLA with a resolution of about 1 arcsec (FWHM). The aim of the project is to use the radio imagery to probe the central kpc of these LIRGs in search of active galactic nuclei (AGN). Methods: We used the archival data at 1.49 and 8.44 GHz to create radio-spectral-index maps using the standard relation between flux density Sν and frequency ν, Sν ~ ν- α, where α is the radio spectral index. By studying the spatial variations in α, we classified the objects as radio-AGN, radio-SB, and AGN/SB (a mixture). We identified the presence of an active nucleus using the radio morphology, deviations from the radio/infrared correlation, and spatially resolved spectral index maps, and then correlated this to the usual mid-infrared ([NeV]/[NeII] and [OIV]/[NeII] line ratios and equivalent width of the 6.2 μm PAH feature) and optical (BPT diagram) AGN diagnostics. Results: We find that 21 out of the 46 objects in our sample (~45%) are radio-AGN, 9 out of the 46 (~20%) are classified as starbursts (SB) based on the radio analysis, and 16 (~35%) are AGN/SB. After comparing to other AGN diagnostics we find 3 objects out of the 46 (~7%) that are identified as AGN based on the radio analysis, but are not classified as such based on

Obscured AGNs in Bulgeless Hosts discovered by WISE: The Case Study of SDSS J1224+5555

NASA Astrophysics Data System (ADS)

Satyapal, S.; Secrest, N. J.; Rothberg, B.; O'Connor, J. A.; Ellison, S. L.; Hickox, R. C.; Constantin, A.; Gliozzi, M.; Rosenberg, J. L.

2016-08-01

There is mounting evidence that supermassive black holes (SMBHs) form and grow in bulgeless galaxies. However, a robust determination of the fraction of active galactic nuclei (AGNs) in bulgeless galaxies, an important constraint to models of SMBH seed formation and merger-free models of AGN fueling, is unknown, since optical studies have been shown to be incomplete for AGNs in low-mass galaxies. In a recent study using the Wide-field Infrared Survey Explorer, we discovered hundreds of bulgeless galaxies that display mid-infrared signatures of extremely hot dust suggestive of powerful accreting massive black holes, despite having no signatures of black hole activity at optical wavelengths. Here we report X-ray follow-up observations of J122434.66+555522.3, a nearby (z = 0.052) isolated bulgeless galaxy that contains an unresolved X-ray source detected at the 3σ level by XMM-Newton with an observed luminosity uncorrected for intrinsic absorption of {L}2-10{keV}=(1.1+/- 0.4)× {10}40 erg s-1. Ground-based near-infrared spectroscopy with the Large Binocular Telescope and multiwavelength observations from ultraviolet to millimeter wavelengths together suggest that J1224+5555 harbors a highly absorbed AGN with an intrinsic absorption of {N}{{H}}\\gt {10}24 cm-2. The hard X-ray luminosity of the putative AGN corrected for absorption is {L}2-10{keV}˜ 3× {10}42 erg s-1, which, depending on the bolometric correction factor, corresponds to a bolometric luminosity of the AGN of {L}{bol}.˜ 6× {10}43-3 × 1044 {erg} {{{s}}}-1 and a lower mass limit for the black hole of {M}{BH}≃ 2× {10}6 {M}⊙ , based on the Eddington limit. While enhanced X-ray emission and hot dust can be produced by star formation in extremely low metallicity environments typical in dwarf galaxies, J1224+5555 has a stellar mass of ˜ 2.0× {10}10 {M}⊙ and an above solar metallicity (12 + {logO}/{{H}} = 9.11), typical of our WISE-selected bulgeless galaxy sample. While collectively these

STUDYING FAINT ULTRA-HARD X-RAY EMISSION FROM AGN IN GOALS LIRGS WITH SWIFT/BAT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koss, Michael; Casey, Caitlin M.; Mushotzky, Richard

2013-03-10

We present the first analysis of the all-sky Swift Burst Alert Telescope (BAT) ultra-hard X-ray (14-195 keV) data for a targeted list of objects. We find that the BAT data can be studied at three-times-fainter limits than in previous blind detection catalogs based on prior knowledge of source positions and using smaller energy ranges for source detection. We determine the active galactic nucleus (AGN) fraction in 134 nearby (z < 0.05) luminous infrared galaxies (LIRGs) from the GOALS sample. We find that LIRGs have a higher detection frequency than galaxies matched in stellar mass and redshift at 14-195 keV andmore » 24-35 keV. In agreement with work at other wavelengths, the AGN detection fraction increases strongly at high IR luminosity with half of the high-luminosity LIRGs (50%, 6/12, log L{sub IR}/L{sub Sun} > 11.8) detected. The BAT AGN classification shows 97% (37/38) agreement with Chandra and XMM-Newton AGN classification using hardness ratios or detection of an iron K{alpha} line. This confirms our statistical analysis and supports the use of the Swift/BAT all-sky survey to study fainter populations of any category of sources in the ultra-hard X-ray band. BAT AGNs in LIRGs tend to show higher column densities with 40% {+-} 9% showing 14-195 keV/2-10 keV hardness flux ratios suggestive of high or Compton-thick column densities (log N{sub H} > 24 cm{sup -2}), compared to only 12% {+-} 5% of non-LIRG BAT AGNs. We also find that using specific energy ranges of the BAT detector can yield additional sources over total band detections with 24% (5/21) of detections in LIRGs at 24-35 keV not detected at 14-195 keV.« less

Chandra Survey of Nearby Galaxies: Testing the Accretion Model for Low-luminosity AGNs

NASA Astrophysics Data System (ADS)

She, Rui; Ho, Luis C.; Feng, Hua; Cui, Can

2018-06-01

From a Chandra sample of active galactic nuclei (AGNs) in nearby galaxies, we find that for low-luminosity AGNs, either the intrinsic absorption column density, or the fraction of absorbed AGNs, positively scales with the Eddington ratio for L bol/L Edd ≲ 10‑2. Such a behavior, along with the softness of the X-ray spectrum at low luminosities, is in good agreement with the picture that they are powered by hot accretion flows surrounding supermassive black holes. Numerical simulations find that outflows are inevitable with hot accretion flows, and the outflow rate is correlated with the innermost accretion rate in the low-luminosity regime. This agrees well with our results, suggesting that the X-ray absorption originates from, or is associated with, the outflow material. Gas and dust on larger scales may also produce the observed correlation. Future correlation analyses may help differentiate the two scenarios.

Long term multiwavelength studies of the corona/disc connection in AGN

NASA Astrophysics Data System (ADS)

Buisson, D.; Lohfink, A.; Alston, W.; Fabian, A.; Gallo, L.; Kara, E.; Zoghbi, A.; Wilkins, D.; Miller, J.; Cackett, E.

2017-10-01

One way of increasing our understanding of AGN is determining the nature of the connection between the optical/UV emitting accretion disc and the X-ray emitting corona. Studies of variability in these two bands are a key tool for gaining insight into the processes involved. We will present results from a sample of long-term AGN monitoring campaigns in the optical, UV and X-ray with Swift. In particular, we will explore UV/optical-X-ray correlations and associated time lags. We will compare these measurements and the UV/optical RMS spectra with theoretical reprocessing models and confront recent claims of the observed lags being longer than those which are expected for a standard thin disc. Additionally, a new Swift monitoring campaign of the z=2 quasar PG 1247+267 allows us to probe the shorter wavelengths at the peak of the accretion disc spectrum, providing information on the region of the disc closest to the black hole. However, not all AGN show such correlations, including IRAS 13224-3809, the subject of a recent 1.5 Ms XMM observation. Using this and other examples, we will explore the possible reasons for the lack of observed correlation.

AGN contamination in total infrared determined star formation rates in dusty galaxies at z~2-3

NASA Astrophysics Data System (ADS)

Mazzei, Renato; Sharon, Chelsea E.; Riechers, Dominik

2017-01-01

Along with theoretical work that suggests feedback from active galactic nuclei (AGN) may quench star formation in massive galaxies, the temporal coincidence between the peak of cosmic star formation rates and black hole accretion rates suggests that AGN are common in star forming galaxies at z~2-3. Since star forming galaxies at these epochs are also very dusty, it is important that we correct galaxies’ long-wavelength properties for the presence of dust-obscured AGN in order to accurately capture their star formation rates and gas characteristics. We present a spectral energy distribution (SED) analysis of several un-lensed z~2-3 dusty star-forming galaxies from Pope et al. (2008) and Coppin et al. (2010), which we compare to several other high-z starbursts with well sampled SEDs. We constructed dust SEDs from existing Spitzer, Herschel, and SCUBA-2 photometry catalogues with data between 3.6 and 850 μm. For the SED fits, we used the Code Investigating GALaxy Emission (CIGALE), since it self-consistently determines the dust attenuation of stars and dust emission in the infrared in addition to determining the dust emission from obscured AGN (Noll et al. 2009; Serra et al. 2011). Our best-fit SEDs have typical reduced χ2 values between 0.2 and ~3. We use the output from CIGALE to determine the fraction of the total infrared luminosity (LTIR 8-1000 um) from star formation and from any potential obscured AGN. In order to examine the effects of buried AGN on the integrated Schmidt-Kennicutt relation (log(LTIR) vs. log(L'CO)), we compare our new LTIR to recently obtained CO(1-0) line luminosities from the Karl G. Jansky Very Large Array. Unaccounted for dust emission from AGN can artificially inflate the star formation rate inferred from LTIR, and may therefore offset starburst galaxies from the local Schmidt-Kennicutt relation and increase the slope of the relation, which can affect the inferred drivers of star formation.

X-ray View of Four High-Luminosity Swift-BAT AGN: Unveiling Obscuration and Reflection with Suzaku

NASA Technical Reports Server (NTRS)

Fiorettil, V.; Angelini, L.; Mushotzky, R. F.; Koss, M.; Malaguti, G.

2013-01-01

Aims. A complete census of obscured Active Galactic Nuclei (AGN) is necessary to reveal the history of the super massive black hole (SMBH) growth and galaxy evolution in the Universe given the complex feedback processes and the fact that much of this growth occurs in an obscured phase. In this context, hard X-ray surveys and dedicated follow-up observations represent a unique tool for selecting highly absorbed AGN and for characterizing the obscuring matter surrounding the SMBH. Here we focus on the absorption and reflection occurring in highly luminous, quasar-like AGN, to study the relation between the geometry of the absorbing matter and the AGN nature (e.g. X-ray, optical, and radio properties), and to help to determine the column density dependency on the AGN luminosity. Methods. The Swift/BAT nine-month survey observed 153 AGN, all with ultra-hard X-ray BAT fluxes in excess of 10(exp -11) erg per square centimeter and an average redshift of 0.03. Among them, four of the most luminous BAT AGN (44.73 less than LogLBAT less than 45.31) were selected as targets of Suzaku follow-up observations: J2246.0+3941 (3C 452), J0407.4+0339 (3C 105), J0318.7+6828, and J0918.5+0425. The column density, scattered/reflected emission, the properties of the Fe K line, and a possible variability are fully analyzed. For the latter, the spectral properties from Chandra, XMM-Newton and Swift/XRT public observations were compared with the present Suzaku analysis, adding an original spectral analysis when non was available from the literature. Results. Of our sample, 3C 452 is the only certain Compton-thick AGN candidate because of i) the high absorption (N(sub H) approximately 4 × 10(exp 23) per square centimeter) and strong Compton reflection; ii) the lack of variability; iii) the "buried" nature, i.e. the low scattering fraction (less than 0.5%) and the extremely low relative [OIII] luminosity. In contrast 3C 105 is not reflection-dominated, despite the comparable column density

Active Galactic Nucleus Feedback in an Elliptical Galaxy with the Most Updated AGN Physics. I. Low Angular Momentum Case

NASA Astrophysics Data System (ADS)

Yuan, Feng; Yoon, DooSoo; Li, Ya-Ping; Gan, Zhao-Ming; Ho, Luis C.; Guo, Fulai

2018-04-01

We investigate the effects of AGN feedback on the cosmological evolution of an isolated elliptical galaxy by performing two-dimensional high-resolution hydrodynamical numerical simulations. The inner boundary of the simulation is chosen so that the Bondi radius is resolved. Compared to previous works, the two accretion modes—namely, hot and cold, which correspond to different accretion rates and have different radiation and wind outputs—are carefully discriminated, and the feedback effects by radiation and wind in each mode are taken into account. The most updated AGN physics, including the descriptions of radiation and wind from the hot accretion flows and wind from cold accretion disks, are adopted. Physical processes like star formation and SNe Ia and II are taken into account. We study the AGN light curve, typical AGN lifetime, growth of the black hole mass, AGN duty cycle, star formation, and X-ray surface brightness of the galaxy. We compare our simulation results with observations and find general consistency. Comparisons with previous simulation works find significant differences, indicating the importance of AGN physics. The respective roles of radiation and wind feedback are examined, and it is found that they are different for different problems of interest, such as AGN luminosity and star formation. We find that it is hard to neglect any of them, so we suggest using the names “cold feedback mode” and “hot feedback mode” to replace the currently used ones.

Disks and cones: interferometry of the dusty and molecular material of AGN on parsec sales

NASA Astrophysics Data System (ADS)

Tristam, Konrad R. W.

2016-08-01

The central engine of Active Galactic Nuclei (AGN) is surrounded by dense molecular and dusty material on parsec scales. Typically referred to as the ""dusty torus"", this material is a key ingredient of AGN because it (1) provides the angle dependent obscuration of the central engine and (2) most likely plays an important role for the accretion of the material onto the supermassive black hole. Observations using interferometry in the infrared have, in the last ten years, resolved and characterised the thermal emission from the dust heated by the AGN beyond simple fits of the spectral energy distribution, leading to a great leap forward in our view of the dusty material surrounding AGN. In general the torus is parsec-sized, with a large scatter in extension between individual objects. Our studies have led to the surprising discovery that the dust emission is clearly separated into two distinct components: an inner disk-like emission region which is surrounded by a polar elongated emitter. I will demonstrate these discoveries using the results obtained for the Circinus galaxy, and discuss how the results for this galaxy compare to other well studied sources. While putting strong constraints on torus models, our findings are in good qualitative agreement with recent hydrodynamic simulations of AGN tori. The next big step forward can be expected from sub-mm interferometry and I will give a short glimpse at the results from our recent ALMA observations of the outer torus in the Circinus galaxy.