Yang, Li; Yan, Jing; Jin, Xiaoqing; Jin, Yu; Yu, Wei; Xu, Shanhu; Wu, Haibin
2016-01-01
This study was conducted to estimate screening performance of dementia screening tools including Mini-Mental State Examination (MMSE), Mini-Cog, Clock Drawing Test (CDT) and Ascertain Dementia 8 questionnaire (AD8) for older adults. 2015 participants aged 65 years or more in eastern China were enrolled. 4 screening tests were administered and scored by specifically trained psychiatrists. We used data from two-by-two tables to calculate the sensitivity, specificity, and positive and negative predictive values (PPV/NPV). Our study showed that dementia was highly prevalent among elderly in Zhejiang province. The Mini-Cog, with excellent screening characteristics and spending less time, could be considered to be used as a screening tool among communities to help to diagnose dementia early. PMID:28006822
Correlates of Level and Change in the Mini-Mental State Examination
ERIC Educational Resources Information Center
Soubelet, Andrea; Salthouse, Timothy A.
2011-01-01
The goal of the current project was to determine (a) the cognitive abilities assessed by the Mini Mental State Examination (MMSE; M. F. Folstein, S. E. Folstein, & P. R. McHugh, 1975), (b) whether the same abilities are associated with MMSE performance among people of different ages, and (c) whether the same abilities are involved in changes…
Santana, Isabel; Duro, Diana; Lemos, Raquel; Costa, Vanessa; Pereira, Miguel; Simões, Mário R; Freitas, Sandra
2016-04-01
Introdução: O Mini-Mental State Examination é o teste de rastreio de défice cognitivo/demência mais difundido. No nosso país têm-se utilizado pontuações de corte definidas por grupos de literacia, mas existem novas propostas sustentadas por estudos mais representativos. Propomo-nos confirmar a influência da idade e da escolaridade no desempenho, avaliar a capacidade discriminativa dos novos dados normativos e testar a acuidade diagnóstica das pontuações de corte validadas para o défice cognitivo ligeiro e para as formas mais prevalentes de demência. Material e Métodos: O estudo incluiu 1 441 participantes escolarizados, divididos em sete subgrupos: Défice cognitivo ligeiro, doença de Alzheimer, demência fronto-temporal, demência vascular, demência com corpos de Lewy, controlo-comunidade e controlo-clínica- memória. Resultados: Em conjunto, idade e escolaridade explicam 10,4% da variância dos resultados no Mini-Mental State Examination, com ambas contribuindo significativamente para a predição dos resultados. A acuidade diagnóstica com base nos dados normativos mais recentes foi sempre superior à conseguida com as pontuações de corte de validação, revelando uma especificidade excelente (superior a 90%) e uma sensibilidade também excelente para a doença de Alzheimer ligeira (91%), boa para demência com corpos de Lewy (78%), baixa para o défice cognitivo ligeiro (65%) e demência fronto-temporal e demência vascular (55%). Discussão e Conclusões: O desempenho no Mini-Mental State Examination é influenciado pela idade e pela escolaridade, apoiando a utilização de dados normativos que considerem estas variáveis. Com esta abordagem, o Mini-Mental State Examination poderá ser um instrumento sensível e específico para o rastreio da doença de Alzheimer em todos os níveis de cuidados de saúde, mas a acuidade de diagnóstico é limitada noutras situações frequentes em consultas especializadas, como o défice cognitivo ligeiro
Correlates of Level and Change in the Mini-Mental State Examination
Soubelet, A.; Salthouse, T. A.
2011-01-01
The goal of the current project was to determine: (1) the cognitive abilities assessed by the Mini Mental State Examination (MMSE); (2) whether the same abilities are associated with MMSE performance among people of different ages, and (3) and whether the same abilities are involved in changes within the same people over time. We therefore examined whether the initial levels of five cognitive ability constructs - Vocabulary, Reasoning, Memory, Space and Speed - predicted initial levels of MMSE, and whether the initial levels or the changes in these five cognitive abilities predicted change in the MMSE. The major findings were that three cognitive constructs, Vocabulary, Reasoning and Memory, contribute to performance in the MMSE, but that their respective contributions to the MMSE vary as a function of age and time. In particular, individual differences and change in the MMSE are primarily related to individual differences in Reasoning among adults under about 70 years of age, while both initial level of MMSE performance and longitudinal change in MMSE primarily related to initial level and change in memory ability among adults over 70 years of age. The results therefore imply that both the level of performance on the MMSE at a single point in time and the change in MMSE over time may represent somewhat different cognitive abilities at different ages. PMID:21480725
Guimarães, Fabiana Costa; Amorim, Paulo Roberto dos Santos; Reis, Fernando Fonseca dos; Bonoto, Robson Teixeira; Oliveira, Wederson Candido de; Moura, Tiago Augusto da Silva; Assis, Cláudia Loures de; Palotás, András; Lima, Luciana Moreira
2015-01-01
In addition to hypertension, dyslipidemia, atherosclerosis, and diabetes, a sedentary lifestyle plays a pivotal role in cerebro- and cardiovascular disease and progressive cognitive decline, including vascular dementia and Alzheimer's disease. The present study investigated whether controlling the key risks and participating in physical activity have a beneficial impact on these disorders. Elderly volunteers were enrolled in a 3-month program that consisted of structured exercise three times per week. The daily routine, medical treatment, and vital parameters were evaluated and correlated with the subjects' neuropsychiatric status. High blood pressure was found in 40% of the participants, with no significant differences between the sexes. A higher proportion of females (55%) than males (18%) forgot to take their medication during the observation period. Significant negative correlations were found between Mini-Mental State Examination (MMSE) scores and age, lack of a caregiver, and increased pulse rate before or after exercise. These results suggest that the presence of home assistance and subsequent improvement in medication compliance, vital parameter optimization, and regular physical activity may yield better MMSE results and a lower risk for cerebro- and cardiovascular disease.
Freidl, W; Schmidt, R; Stronegger, W J; Irmler, A; Reinhart, B; Koch, M
1996-01-01
Age and education have been found to affect the Mini Mental State Examination (MMSE) score of elderly normals, but there have been no studies assessing the influence of environmental and behavioral factors on this test. We therefore administered the MMSE to 1437 normal elderly subjects in the setting of a stroke prevention study and correlated their results to 16 sociodemographic, environmental, and behavioral factors, and vascular risk factors. Study statistics composed of a multiple logistic regression analysis and graphical models revealed the relations between variables in greater detail. Logistic regression yielded education level, occupational status, living as a single, general life stress, physical strain, and physical inactivity to be independent predictors of the MMSE score. Age was not included in this model. Graphical models demonstrated similar results, but did not include living as a single and physical inactivity. As shown in our independence graph, general life stress is the crucial predictor and links other environmental and sociodemographic variables with the test performance of elderly normals.
Validation Study of the Mini-Mental State Examination in Urdu Language for Pakistani Population
Awan, Safia; Shahbaz, Naila; Akhtar, Syed Wasim; Ahmad, Arsalan; Iqbal, Sadaf; Ahmed, Sellal; Naqvi, Haider; Wasay, Mohammad
2015-01-01
Validation study of the Mini-Mental State Examination in Urdu language for Pakistani population Objective: This study was conducted primarily to validate and determine the optimal cutoff score in the diagnosis of dementia among Pakistani’s and study the effects of gender and education on the MMSE performance in our population. Methods: Four hundred participants took part in the study. Patient with dementia recruited from five major hospitals from Pakistan. The MMSE was translated into Urdu. Results: There were 61 men and 39 women in dementia group and 225 men and 75 women in the control group. The mean score of Urdu MMSE were lower in patients with dementia 18.5 ± 5.6 (range 0-30) as compared to the controls 26.8 ± 2.6 (range 7-30). This difference between groups was statistically significant (p<0.001). Educational based MMSE score below 15 yielded perfect sensitivity and specificity for the diagnosis of dementia. Conclusions: These finding confirm the influence of level of education on MMSE score and education stratified cutoff scores should be used while screening for cognitive impairment in this population. PMID:26191094
2009-01-01
Background This study evaluated the frequency of cognitive impairment in patients with Fibromyalgia syndrome (FMS) using the Mini Mental State Examination (MMSE). Methods We analyzed baseline data from all 46 patients with FMS and 92 age- and sex-matched controls per diagnosis of neuropathic (NeP) or mixed pain (MP) selected from a larger prospective study. Results FMS had a slight but statistically significant lower score in the adjusted MMSE score (26.9; 95% CI 26.7-27.1) than either NeP (27.3; 95% CI 27.2-27.4) or MP (27.3; 27.2-27.5). The percentage of patients with congnitive impairment (adjusted MMSE ≤ 26) was numerically higher in FMS (15%; 95% CI 6.3-29) compared with NeP (5%; 95% CI 1.8-12.2) or MP (5%; 95% CI 1.8-12.2) and higher than in the same age stratum of the general population (0.05%). Conclusions Compared with the population reference value, patients with FMS showed high frequency of cognitive impairment. PMID:20025750
Matallana, Diana; de Santacruz, Cecilia; Cano, Carlos; Reyes, Pablo; Samper-Ternent, Rafael; Markides, Kyriakos S; Ottenbacher, Kenneth J; Reyes-Ortiz, Carlos A
2011-03-01
To study the effect of education and language of response at the interview on performance in the Mini-Mental State Examination (MMSE) domains, we studied 2861 Mexican Americans aged 65 and older from the Hispanic Established Populations for Epidemiologic Studies of the Elderly (EPESE) followed from 1993 to 1994 until 2004 to 2005. The MMSE was examined as total score (0-30) or divided into 2 global domains: (1) no-memory (score 0-24): Orientation, attention, and language; and (2) memory (score 0-6): working and delayed memory. Mean age and total MMSE were 72.7 years and 24.6 at baseline, and 81.7 years and 20.5 at 11 years of follow-up. Spanish-speaking participants had less education (4.1 vs 7.4 years, P < .0001), they had significantly higher adjusted mean scores for memory, no-memory, and total MMSE compared with English-speaking participants. In multivariate longitudinal analyses, participants with more years of education performed better than those with less education, especially in total MMSE and no-memory domain. Spanish-speaking participants with 4 to 6 years of education had higher memory scores than those speaking English (estimate 0.40, standard error [SE] = 0.14, P < .001), 7 to 11 (estimate 0.27, standard error = 0.13, P < .01) or 12+ (estimate 0.44, standard error = 0.13, P < .001). Results suggest that cultural factors and variables related to preferred language use determined variations in MMSE performance. Because the memory domain of the MMSE is less affected by education, it may be used along with other cognitive tests for early detection of cognitive decline in older populations with low education.
Matallana, Diana; de Santacruz, Cecilia; Cano, Carlos; Reyes, Pablo; Samper-Ternent, Rafael; Markides, Kyriakos S.; Ottenbacher, Kenneth J.; Reyes-Ortiz, Carlos A.
2011-01-01
To study the effect of education on the performance in the Mini-Mental State Examination (MMSE) domains, we included 2,861 Mexican Americans aged 65 and older from the Hispanic Established Populations for Epidemiologic Studies of the Elderly (EPESE) followed from 1993–1994 until 2004–2005. The MMSE was examined as total score (0–30) or divided in two global domains: 1) no-memory (score 0–24): Orientation, attention, and language; and 2) memory (score 0–6): working and delayed memory. Mean age and total MMSE were 72.7 and 24.6 at wave 1, and 81.7 and 20.5 at wave 5. Spanish speaking subjects had lower years of education (4.1 vs. 7.4, p<.0001), they had significantly higher adjusted (by age, education, and gender) mean scores for memory, no-memory and the total MMSE compared with English speaking subjects across the five waves of follow-up. In multivariate longitudinal analyses over 11 years of follow-up, subjects with more years of education performed better than those less educated, especially in no-memory and the total MMSE. Spanish speaking subjects with 4–6 years of education had higher memory scores than those speaking English (estimate 0.40, standard error [SE] = 0.14, p<.001), 7–11 (estimate 0.27, SE= 0.13, p<.01) or 12+ (estimate 0.44, SE= 0.13, p<.001). This suggests that cultural factors and factors related to preferred language use may determine variations in MMSE performance. Since the memory domain of the MMSE is less affected by education, it may be used along with other cognitive tests in older populations with low education. PMID:20538969
Solias, A; Skapinakis, P; Degleris, N; Pantoleon, M; Katirtzoglou, E; Politis, A
2014-01-01
For the last 38 years, Mini Mental State Examination (MMSE) has been widely used as a dementia screening measure in everyday clinical practice as well as in both cohort and cross-sectional studies. Its validity and reliability for the Greek population has explicitly been documented. However, the effect of age and education on the subject's performance makes it necessary to reckon them in the estimation of the "cutoff score". The purpose of this study is to estimate the prevalence of dementia in Greek population and determine the "cutoff score" by age and education-corrected norms. Cross sectional study of 630 patients older than 55 years, who live independently in Ilion and Helioupolis Municipalities was conducted, 27.3% of the subjects tested in the study were diagnosed with memory disorder according to their MMSE scores and the validation for the Greek population. The effect of age and education to the subjects' performance was statistically significant (p=.000). The use of standard "cutoff score" was not proved to be useful for the personalized interpretation of the results, as documented by the fact that older individuals with lower education had a poorer performance relatively to younger, highly educated subjects. Comparatively to the group age of 55-60 years, the odds ratio after the age of 75 years varies from 2.58 to 4.91. Regarding the variable factor of education, the odds ratio for the first degree education graduates decreases from 1.43 to 3.19 for the third degree education graduates in comparison with the group of illiterates. In conclusion, the use of the "cutoff score" algorithm and the simultaneous estimation of age and education effect on MMSE score may prove useful for the proper evaluation of MMSE performance. According to the age and education of examine candidates in the community and the primary care, we propose the use of the 25th percentile as a more useful cutoff score in order to decrease the false positive results.
Lucchi, E; Minicuci, N; Magnifico, F; Mondini, S; Calza, A; Avanzi, S; Villani, D; Bellelli, G; Trabucchi, M
2004-01-01
The improvement in cognitive performances due to cholinesterase inhibitors (ChEls) is not homogeneous among Alzheimer's disease (AD) subjects. Aim of this study is to evaluate whether a specific pattern of change in mini mental state examination (MMSE) could be observed in AD subjects after 9-month treatment with ChEls. From September 2000 to September 2002, 99 subjects enrolled in the CRONOS project. They have never been previously treated with ChEls. All of them completed both the 3- and the 9-month follow-up. The multidimensional assessment included MMSE, activity of daily living (ADL), instrumental activity of daily living (IADL), somatic health status, according to design of the CRONOSproject. The MMSE was analyzed both as a total score and disaggregated in 11 items. All subjects were divided in 2 groups according to the degree of change in MMSE total score from baseline to the 9th month. Subjects with a change 0 as responders (R). At start, no statistically significant differences were found between the 2 groups. MMSE score was significantly higher in the R group both at 3 (p < 0.0001) and 9 months (p < 0.0001), while functional status (ADL and IADL) was significantly lower in NR group at 9 months (p = 0.025; p =0.018, respectively). In MMSE qualitative analysis of 3-month, NR significantly worsened in temporal (p
Dai, Ting; Davey, Adam; Woodard, John L; Miller, Lloyd Stephen; Gondo, Yasuyuki; Kim, Seock-Ho; Poon, Leonard W
2013-08-01
Centenarians represent a rare but rapidly growing segment of the oldest-old. This study presents item-level data from the Mini-Mental State Examination (MMSE) in a cross-sectional, population-based sample of 244 centenarians and near-centenarians (aged 98-108, 16% men, 21% African-American, 38% community dwelling) from the Georgia Centenarian Study (2001-2008) according to age, education, sex, race, and residential status. Multiple-Indicator Multiple-Cause (MIMIC) models were used to identify systematic domain-level differences in MMSE scores according to demographic characteristics in this age group. Indirect effects of age, educational attainment, race, and residential status were found on MMSE scores. Direct effects were limited to concentration for education and race and orientation for residential status. Mean levels of cognitive functioning in centenarians were low, with mean values below most commonly-used cutoffs. Overall scores on the MMSE differed as a function of age, education, race, and residential status, with differences in scale performance limited primarily to concentration and orientation and no evidence of interactions between centenarian characteristics. Adjusting for education was not sufficient to account for differences according to race, and adjusting for residential status was not sufficient to account for differences according to age.
Silber
1999-01-01
The purpose of this study was to determine whether background music had an influence on the scores of patients with Alzheimer's disease during the Mini Mental State Examination (MMS). Eighteen patients diagnosed with dementia from a day care center participated in the study. Eleven (experimental group) were examined 3 times, each time 1 month apart. The first examination, called pretest, served as a baseline and was done without background music. The second and third examinations (test and posttest) were done with background music. Seven people (control group) were examined 3 times, each time one-month apart. The three tests (pretest, test, posttest) were done without background music. The Wilcoxon matched-pairs test was used to compare the results within each group. No significant differences were found between the three tests for both groups. The Mann-Whitney test was used to compare the results between the experimental and control groups. No significant differences were found between these two groups. This suggests that background music used with persons affected by dementia at this second stage of the disease plays a neutral role during the MMS. Another suggestion is that perhaps people at this stage of the disease do not feel any stress or threat that may have an impact on their concentration during the MMS. Other suggestions are made for possible further research.
Helmi, Luqman; Meagher, David; O’Mahony, Edmond; O’Neill, Donagh; Mulligan, Owen; Murthy, Sutha; McCarthy, Geraldine; Adamis, Dimitrios
2016-01-01
AIM To explore the agreement between the mini-mental state examination (MMSE) and montreal cognitive assessment (MoCA) within community dwelling older patients attending an old age psychiatry service and to derive and test a conversion formula between the two scales. METHODS Prospective study of consecutive patients attending outpatient services. Both tests were administered by the same researcher on the same day in random order. RESULTS The total sample (n = 135) was randomly divided into two groups. One to derive a conversion rule (n = 70), and a second (n = 65) in which this rule was tested. The agreement (Pearson’s r) of MMSE and MoCA was 0.86 (P < 0.001), and Lin’s concordance correlation coefficient (CCC) was 0.57 (95%CI: 0.45-0.66). In the second sample MoCA scores were converted to MMSE scores according to a conversion rule from the first sample which achieved agreement with the original MMSE scores of 0.89 (Pearson’s r, P < 0.001) and CCC of 0.88 (95%CI: 0.82-0.92). CONCLUSION Although the two scales overlap considerably, the agreement is modest. The conversion rule derived herein demonstrated promising accuracy and warrants further testing in other populations. PMID:27679776
Dinomais, Mickael; Celle, Sebastien; Duval, Guillaume T.; Roche, Frederic; Henni, Samir; Bartha, Robert; Beauchet, Olivier
2016-01-01
The clinical utility of the Mini-Mental State Examination (MMSE) and its shorter version (SMMSE) is still debated. There is a need to better understand the neuroanatomical correlates of these cognitive tests. The objective of this cross-sectional study was to determine whether lower MMSE and SMMSE scores correlated with focal brain volume reduction in older adults. Participants from the GAIT study (n = 207; mean, 70.9±5.9 years; 57% female; mean MMSE 26.2±3.9; mean SMMSE 5.1±1.1) were evaluated using the MMSE and SMMSE and received a 1.5-Tesla MRI scan of the brain. Cortical gray and white matter subvolumes were automatically segmented using Statistical Parametric Mapping. Age, gender, education level, and total intracranial volume were included as potential confounders. We found correlations between the MMSE score and specific cortical regions of the limbic system including the hippocampus, amygdala, cingulate gyrus, and parahippocampal gyrus, independently of the diagnostic category (i.e., mild cognitive impairment or Alzheimer disease or controls). Regarding correlations with the SMMSE score, only one cluster in the left hippocampus was identified, which overlapped with the cluster that was positively correlated with the MMSE score. There were no correlations with the volume of white matter. In conclusion, worse MMSE and SMMSE scores were associated with gray matter atrophy mainly in the limbic system. This finding highlights that atrophy of specific brain regions are related to performance on the MMSE and the SMMSE tests, and provides new insights into the cognitive function probed by these tests. PMID:27741236
Su, Yu-Ping; Chang, Chin-Kuo; Hayes, Richard D.; Perera, Gayan; Broadbent, Matthew; To, David; Hotopf, Matthew; Stewart, Robert
2014-01-01
Background Lower levels of cognitive function have been found to be associated with higher mortality in older people, particularly in dementia, but the association in people with other mental disorders is still inconclusive. Methods and Findings Data were analysed from a large mental health case register serving a geographic catchment of 1.23 million residents, and associations were investigated between cognitive function measured by the Mini-Mental State Examination (MMSE) and survival in patients aged 65 years old and over. Cox regressions were carried out, adjusting for age, gender, psychiatric diagnosis, ethnicity, marital status, and area-level socioeconomic index. A total of 6,704 subjects were involved, including 3,368 of them having a dementia diagnosis and 3,336 of them with depression or other diagnoses. Descriptive outcomes by Kaplan-Meier curves showed significant differences between those with normal and impaired cognitive function (MMSE score<25), regardless of a dementia diagnosis. As a whole, the group with lower cognitive function had an adjusted hazard ratio (HR) of 1.42 (95% CI: 1.28, 1.58) regardless of diagnosis. An HR of 1.23 (95% CI: 1.18, 1.28) per quintile increment of MMSE was also estimated after confounding control. A linear trend of MMSE in quintiles was observed for the subgroups of dementia and other non-dementia diagnoses (both p-values<0.001). However, a threshold effect of MMSE score under 20 was found for the specific diagnosis subgroups of depression. Conclusion Current study identified an association between cognitive impairment and increased mortality in older people using secondary mental health services regardless of a dementia diagnosis. Causal pathways between this exposure and outcome (for example, suboptimal healthcare) need further investigation. PMID:25184819
Rosselli, Mónica; Tappen, Ruth; Williams, Christine; Salvatierra, Judy
2006-10-01
The Mini-Mental State Examination (MMSE) [Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975). Mini-Mental State: A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189-198] has frequently been challenged for its bias against individuals with lower levels of education and the use of scoring adjustments for lower educational levels has become standard practice [Ostrosky-Solis, F., Lopez-Arango, G., & Ardila, A. (2000). Sensitivity and specificity of the Mini Mental State Examination in a Spanish-speaking population. Applied Neuropsychology, 7, 25-31]. An additional source of concern is that original instructions specify that the "serial 7's" item may be replaced by an apparently less difficult "backwards spelling" task. This study compared the performance on these items and the effects for total scores on 102 unimpaired and 58 memory impaired elder Hispanic individuals (age 54-98), divided into 3 groups based on educational level (<7, 7-11, and >11 years of education). The effects of education and gender on the total MMSE scores were analyzed using the "serial 7's" and the "backwards spelling" items. For all the studied groups, MMSE scores were higher by an average of 1.5 points when using the "backwards spelling" task. Correlation between "serial 7's" and "backwards spelling" was a modest .37. Education had a significant effect on the MMSE scores in both the impaired and the unimpaired groups. After controlling for education, gender also explains a significant proportion of the variance of the results. The "backwards spelling" and "serial 7's" items do not appear to be either equivalent in difficulty or to test the same abilities in the unimpaired and the impaired Hispanics elders tested in this study.
Mant, A; Eyland, E A; Pond, D C; Saunders, N A; Chancellor, A H
1988-09-01
In a study of 226 elderly residents in a retirement village in Sydney, Australia, general practitioners' opinions about dementia status had high positive and negative predictive values and high specificity, but low sensitivity when evaluated against the mini-mental state examination and the Blessed dementia rating scale. General practitioners were found to disagree with these two measures more often when patients were in advanced old age, and when they considered the patients to be depressed. We conclude that the general practitioner can increase his or her sensitivity to dementia in the elderly by use of either measure.
Contador, I; Bermejo-Pareja, F; Fernández-Calvo, B; Boycheva, E; Tapias, E; Llamas, S; Benito-León, J
2016-05-01
The 37-item version of the Mini-Mental State Examination (MMSE-37) is an extended version of the original test for individuals with low education, which was adapted for different cultures. Despite its favorable psychometric properties, there is a lack of normative data for this instrument. We provide normative data for the MMSE-37 stratified by age, sex, and education in a large population-based cohort of older Spanish adults. The sample consisted of 3,777 participants without dementia (age range: 65-97 years) from different socioeconomic areas of central Spain. Normative data are presented in percentile ranks and divided into nine overlapping age tables with different midpoints, using the overlapping cell procedure. A hierarchical regression was performed to evaluate the effects of sociodemographic variables on MMSE-37 performance. Results showed that age, sex, and education affect test score. The norms presented herein are important for the correct interpretation of MMSE-37 scores when assessing older adults in Spain.
Alcalay, Roy N.; Mejia-Santana, Helen; Tang, Ming X.; Rakitin, Brian; Rosado, Llency; Ross, Barbara; Verbitsky, Miguel; Kisselev, Sergey; Louis, Elan D.; Comella, Cynthia; Colcher, Amy; Jennings, Danna; Nance, Martha; Bressman, Susan; Scott, William K.; Tanner, Caroline; Mickel, Susan; Andrews, Howard; Waters, Cheryl; Fahn, Stanley; Cote, Lucien; Frucht, Steven; Ford, Blair; Rezak, Michael; Novak, Kevin; Friedman, Joseph; Pfeiffer, Ronald; Marsh, Laura; Hiner, Bradley; Siderowf, Andrew; Ottman, Ruth; Clark, Lorraine; Marder, Karen; Caccappolo, Elise
2010-01-01
While little is known about risk factors for cognitive impairment in early onset Parkinson disease (EOPD), postmortem studies have shown an association between dementia with Lewy bodies (DLB) and glucocerebrosidase (GBA) mutation. We compared Mini-Mental State Examination (MMSE) performance and self-reported cognitive impairment in 699 EOPD participants genotyped for mutations in parkin (PRKN), leucine-rich repeat kinase-2 (LRRK2), and GBA. Logistic regression was used to assess the association between reported cognitive impairment and MMSE score, as well as between GBA group membership and self-reported impairment and MMSE. GBA carriers reported more impairment, but MMSE performance did not differ among genetic groups. Detailed neuropsychological testing is required to explore the association between cognitive impairment and GBA mutations. PMID:20182943
Fillenbaum, G G; Heyman, A; Wilkinson, W E; Haynes, C S
1987-09-01
The Mini-Mental State Examination (MMSE) and the Blessed Orientation-Memory-Concentration test (BOMC), a six-item derivative of the Blessed Information-Memory-Concentration Test, were each administered to 36 patients with a clinical diagnosis of Alzheimer's disease. In 24 patients, both tests were readministered a month later. The correlation between the MMSE and BOMC was -0.83 with a test-retest correlation of 0.89 (MMSE) and 0.77 (BOMC). Factor analysis indicated that the multiple MMSE cognitive components could be explained by two factors, which together accounted for 66% of the variance. These factors are conceptually similar to the components of the BOMC, and so may explain the substantial correlation between the two tests. Since these cognitive status tests seem to be equivalent for Alzheimer patients, the briefer measure (BOMC), which offers additional advantages, may be preferred.
Jeong, Seul-Ki; Cho, Ki-Hyun; Kim, Jae-Min
2004-01-01
Background We assessed whether the Korean version of modified Mini-Mental State Examination (K-mMMSE) has improved performance as a screening test for cognitive impairment or dementia in a general population compared with the Korean Mini-Mental State Examination (K-MMSE). Methods Screening interviews were conducted with people aged 65 and over in Noam-dong, Namwon-city, Jeonbuk province. There were 522 community participants, of whom 235 underwent clinical and neuropsychological examination for diagnosis of dementia and Cognitive Impairment No Dementia (CIND). Sensitivity, specificity and areas under the receiver operating characteristic (ROC) curves for the K-mMMSE and the K-MMSE were the main outcome measures. Results Cronbach's alpha for the K-mMMSE was 0.91, compared with 0.84 for the K-MMSE. The areas under the ROC curves in identifying all levels of CIND or dementia were 0.91 for the K-mMMSE and 0.89 for the K-MMSE (P < 0.05). For the K-mMMSE, the optimal cut-off score for a diagnosis of CIND was 69/70, which had a sensitivity of 0.86 and a specificity of 0.79, while, for a diagnosis of dementia, the optimal cut-off score of 59/60 had a sensitivity of 0.91 and a specificity of 0.78. The K-mMMSE also had a high test-retest reliability (r = 0.89). Conclusion Our findings indicate that the K-mMMSE is more reliable and valid than the K-MMSE as a cognitive screen in a population based study of dementia. Considering the test characteristics, the K-MMSE and modified version are expected to be optimally used in clinical and epidemiologic fields. PMID:15283869
Ong, Hui Lin; Subramaniam, Mythily; Abdin, Edimansyah; Wang, Peizhi; Vaingankar, Janhavi Ajit; Lee, Siau Pheng; Shafie, Saleha; Seow, Esmond; Chong, Siow Ann
2016-07-30
Studies have found that age and education were associated with cognition in older adults. However, little is known how clinical factors (e.g. age of illness onset, length of hospital stay, type of antipsychotic medications, and duration of illness) are associated with cognitive functioning in patients with schizophrenia. This study aimed to examine the influence of socio-demographic and clinical factors on cognitive domains measured using Mini-Mental State Examination (MMSE) among patients with schizophrenia or schizoaffective disorders residing in a psychiatric institute in Singapore. A single-phase interview was conducted at the Institute of Mental Health (IMH) in patients diagnosed with schizophrenia or schizoaffective disorders (n=110). MMSE was administered to all participants. Data on socio-demographic characteristics, smoking, alcohol consumption, and medical history were collected. Age, gender, and level of education were significantly associated with MMSE scores. After adjusting for all socio-demographic correlates, longer length of hospital stay remained significant in predicting lower MMSE scores. Length of hospital stay was independently associated with cognitive functioning. Early interventions for cognition such as physical and mental exercises should be implemented for better prognosis.
Nakatsuka, Hiroki; Matsubara, Ichirou; Ohtani, Haruhiko
2003-04-01
The aim of this single photon emission computed tomography(SPECT) study was to determine the abnormality of the regional cerebral blood flow(rCBF) using a three-dimensional stereotactic surface projection (3 D-SSP) in 18 patients who were referred to the hospital because of forgetfulness. Two intergroup comparison by 3 D-SSP analysis was conducted based on MRI, kana pick-out test and Mini-Mental State Examination (MMSE) results. Of the MRI findings, in the brain atrophy group, rCBF was decreased in the posterior cingulate gyrus, medial temporal structure and parieto-temporal association cortex; these rCBF-decreased areas are similar to the Alzheimer disease pattern. In the group where the MMSE was normal but the kana pick-out test was abnormal, rCBF was decreased in the posterior cingulate gyrus and cinguloparietal transitional area. In the group where both the MMSE and kana pick-out test were abnormal, rCBF was decreased in the parieto-temporal association cortex, temporal cortex and medial temporal structure. These results suggest that 3 D-SSP analysis of the SPECT with MMSE and the kana pick-out test provides the possibility of early diagnosis of initial stage of Alzheimer's disease.
Pradier, Christian; Sakarovitch, Charlotte; Le Duff, Franck; Layese, Richard; Metelkina, Asya; Anthony, Sabine; Tifratene, Karim; Robert, Philippe
2014-01-01
The aim of this study was firstly to describe the MMSE (Mini-Mental State Examination) score upon initial diagnosis of Alzheimer's disease and related disorders among the French population, according to age. Secondly, education, gender and place of residence were studied as factors potentially associated with delayed Alzheimer's disease diagnosis. Design we conducted a cross sectional analysis of the French National Alzheimer database (BNA). Data from 2008 to 2012 were extracted. Patients were selected at the moment of their first diagnosis of AD (n = 39,451). Results The MMSE score at initial diagnosis dropped significantly with increasing age. The test score increased with the degree of educational background regardless of age. Gender and place of residence were significantly related to the MMSE score, women and persons living in medical institutions having lower MMSE scores under the age of 90 years and at all educational levels. Conclusions Health care professionals should be aware of these risk factors in order to maximize chances of earliest possible diagnosis of Alzheimer's disease and related disorders. PMID:25093735
Shibamoto, Yuta Baba, Fumiya; Oda, Kyota; Hayashi, Shinya; Kokubo, Masaki; Ishihara, Shun-Ichi; Itoh, Yoshiyuki; Ogino, Hiroyuki; Koizumi, Masahiko
2008-11-15
Purpose: To determine the incidence of brain atrophy and dementia after whole-brain radiotherapy (WBRT) in patients with brain metastases not undergoing surgery. Methods and Materials: Eligible patients underwent WBRT to 40 Gy in 20 fractions with or without a 10-Gy boost. Brain magnetic resonance imaging or computed tomography and Mini-Mental State Examination (MMSE) were performed before and soon after radiotherapy, every 3 months for 18 months, and every 6 months thereafter. Brain atrophy was evaluated by change in cerebrospinal fluid-cranial ratio (CCR), and the atrophy index was defined as postradiation CCR divided by preradiation CCR. Results: Of 101 patients (median age, 62 years) entering the study, 92 completed WBRT, and 45, 25, and 10 patients were assessable at 6, 12, and 18 months, respectively. Mean atrophy index was 1.24 {+-} 0.39 (SD) at 6 months and 1.32 {+-} 0.40 at 12 months, and 18% and 28% of the patients had an increase in the atrophy index by 30% or greater, respectively. No apparent decrease in mean MMSE score was observed after WBRT. Individually, MMSE scores decreased by four or more points in 11% at 6 months, 12% at 12 months, and 0% at 18 months. However, about half the decrease in MMSE scores was associated with a decrease in performance status caused by systemic disease progression. Conclusions: Brain atrophy developed in up to 30% of patients, but it was not necessarily accompanied by MMSE score decrease. Dementia after WBRT unaccompanied by tumor recurrence was infrequent.
Li, Yi; Tian, Xue; Xiong, Zu-Ying; Liao, Jin-Lan; Hao, Li; Liu, Gui-Ling; Ren, Ye-Ping; Wang, Qin; Duan, Li-Ping; Zheng, Zhao-Xia; Quan, Wen-Xiang; Dong, Jie
2016-01-01
Purpose While Cognitive impairment (CI) has been identified as an independent risk factors for mortality in patients undergoing peritoneal dialysis (PD), it is inadequately assessed. We evaluated the applicability of the Modified Mini-Mental State Examination (3MS) in assessing specific cognitive function and compared it to a detailed neuropsychological test battery as the reference standard. Methods In this multicentric cross-sectional study, we enrolled 445 clinically stable patients from five PD units, who were undergoing PD for at least 3 months. The 3MS was evaluated for general cognitive function. A detailed neuropsychological battery including domains of immediate memory, delayed memory, executive function, language, and visuospatial ability were evaluated as reference standards. Sensitivity and specificity of the 3MS was determined by using receiver operating characteristic (ROC) analysis. Results The CI prevalence evaluated by 3MS was 23.6%. PD patients with CI performed worse in all cognitive domains. The 3MS correlated well with specific cognitive domains. However, 18.5%, 57.4%, 12.6%, 8.8%, and 41.2% of patients whom were idendified as normal by 3MS still showed executive dysfunction, immediate memory impairment, delayed memory impairment, and language-ability and visuospatial-ability impairment, respectively. The 3MS identified patients having specific cognitive dysfunction with varied extent of diagnostic value, with 0.50, 0.42, 0.35, 0.34, and 0.26 of Youden index in executive function, delayed memory, language ability, immediate memory, and visuospatial ability, respectively. Conclusions The 3MS is not a comprehensive instrument for major cognitive domains in PD patients. It could, however, be used for executive dysfunction and delayed memory impairment screening. PMID:27911914
Yakoot, Mostafa; Salem, Amel; Helmy, Sherine
2013-01-01
Background Mild cognitive impairment encompasses the clinical continuum between physiologic age-related cognitive changes and dementia. A variety of medications, including herbal preparations (in particular Ginkgo biloba and Panax ginseng), have been advocated as treatments for cognitive impairment in the elderly. In this study, we investigated the effect of an already marketed dietary supplement (Memo®) combining 750 mg of lyophilized royal jelly with standardized extracts of G. biloba 120 mg and P. ginseng 150 mg on Mini-Mental State Examination (MMSE) scores in patients with mild cognitive impairment. Methods Sixty-six subjects presenting with forgetfulness and satisfying the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision (DSM-IV-TR) clinical criteria for mild cognitive impairment were randomly divided into an experimental group treated with one Memo capsule before breakfast daily for 4 weeks and a control group who took placebo. The mean change in MMSE score from baseline and reported adverse effects were compared between the two groups. Results The mean change in MMSE score in the group treated with Memo for 4 weeks was significantly greater than in the control group (+2.07 versus +0.13, respectively) by the Student’s t-test (t = 6.485, P < 0.0001). This was also true after adjusting for age as a covariate and educational level as a factor nested within the treatment groups in a general linear model (analysis of covariance, F = 9.675 [corrected model], P < 0.0001). Conclusion This combined triple formula may be beneficial in treating the cognitive decline that occurs during the aging process as well as in the early phases of pathologic cognitive impairment typical of insidious-onset vascular dementia and in the early stages of Alzheimer’s disease. Larger-sized studies with longer treatment durations are needed to confirm this. PMID:23950642
Hawkins, Keith A; Cromer, Jennifer R; Piotrowski, Andrea S; Pearlson, Godfrey D
2011-11-01
The Mini-Mental State Exam (MMSE) is a clinically ubiquitous yet incompletely standardized instrument. Though the test offers considerable examiner leeway, little data exist on the normative consequences of common administration variations. We sought to: (a) determine the effects of education, age, gender, health status, and a common administration variation (serial 7s subtraction vs. "world" spelled backward) on MMSE score within a minority sample, (b) provide normative data stratified on the most empirically relevant bases, and (c) briefly address item failure rates. African American citizens (N = 298) aged 55-87 living independently in the community were recruited by advertisement, community recruitment, and word of mouth. Total score with "world" spelled backward exceeded total score with serial 7s subtraction across all levels of education, replicating findings in Caucasian samples. Education is the primary source of variance on MMSE score, followed by age. In this cohort, women out-performed men when "world" spelled backward was included, but there was no gender effect when serial 7s subtraction was included in MMSE total score. To ensure an appropriate interpretation of MMSE scores, reports, whether clinical or in publications of research findings, should be explicit regarding the administration method. Stratified normative data are provided.
Ntafouli, Maria; Economou, Nikolaos-Tiberios; Gourgoulianis, Konstantinos; Steiropoulos, Paschalis
2016-01-01
Background Patients with obstructive sleep apnea-hypopnea syndrome (OSAHS), may have cognitive impairment, which usually is not diagnosed, affecting negatively their daily functioning. Aim of this study was to assess the scores of Addenbrooke (ACE-R), Montreal Cognitive Assessment (MoCA), and Mini-Mental State Examination (MMSE), three diagnostic tools for detecting neuropsychological deficits, in patients with OSAHS. Methods Included were 101 patients with OSAHS, diagnosed with polysomnography, who visited the outpatient Sleep Clinic of the University General Hospital of Larissa and General Hospital “Evangelismos” of Athens and 40 normal controls of the general population. All participants filled the ACE-R, MoCA and MMSE scales. Results The majority of patients were males (52.5%), between the ages of 51–71 years (52.4%), secondary school graduates (53.5%). Apnea hypopnea index (AHI) was not correlated with any of the scales: MMSE (P=0.657), ACE-R (P=0.773), MoCA (P=0.465), while these 3 scales correlated well with each other. Conclusions Further research is necessary to evaluate the utility of ACE-R, MoCA and MMSE neuropsychological scales in assessing cognitive impairment of OSAHS patients.
Baek, Min Jae; Kim, Karyeong; Park, Young Ho; Kim, SangYun
2016-01-01
Objective To examine the validity and reliability of the MMSE-2 for assessing patients with mild cognitive impairment (MCI) and Alzheimer’s disease (AD) in a Korean population. Specifically, the usefulness of the MMSE-2 as a screening measure for detecting early cognitive change, which has not been detectable through the MMSE, was examined. Methods Two-hundred and twenty-six patients with MCI, 97 patients with AD, and 91 healthy older adults were recruited. All participants consented to examination with the MMSE-2, the MMSE, and other detailed neuropsychological assessments. Results The MMSE-2 performed well in discriminating participants across Clinical Dementia Rating (CDR) stages and CDR-Sum of Boxes (CDR-SOB), and it showed excellent internal consistency, high test-retest reliability, high interrater reliability, and good concurrent validity with the MMSE and other detailed neuropsychological assessments. The MMSE-2 was divided into two factors (tests that are sensitive to decline in cognitive functions vs. tests that are not sensitive to decline in cognitive functions) in normal cognitive aging. Moreover, the MMSE-2 was divided into two factors (tests related overall cognitive functioning other than memory vs. tests related to episodic memory) in patients with AD. Finally, the MMSE-2 was divided into three factors (tests related to working memory and frontal lobe functioning vs. tests related to verbal memory vs. tests related to orientation and immediate recall) in patients with MCI. The sensitivity and specificity of the three versions of the MMSE-2 were relatively high in discriminating participants with normal cognitive aging from patients with MCI and AD. Conclusion The MMSE-2 is a valid and reliable cognitive screening instrument for assessing cognitive impairment in a Korean population, but its ability to distinguish patients with MCI from those with normal cognitive aging may not be as highly sensitive as expected. PMID:27668883
Kasai, Mari; Meguro, Kenichi; Nakamura, Kei; Nakatsuka, Masahiro; Ouchi, Yoshitaka; Tanaka, Naofumi
2012-01-01
Aims To examine the effectiveness of the Montreal Cognitive Assessment (MoCA) to screen people with mild cognitive impairment (MCI), to associate the MoCA score with the presence of infarction, and to detect the characteristics of people with very mild subcortical vascular dementia (vmSVD). Methods 392 out of 886 community dwellers aged 75 years and above living in Kurihara, Northern Japan, agreed to participate in our study; 164 scored a Clinical Dementia Rating (CDR) of 0 (healthy), 184 scored a CDR of 0.5 (MCI) and 44 scored a CDR of 1+ (dementia). The participants scoring a CDR of 0.5 were divided into 2 subtypes: 37 had vmSVD and 147 had other types of dementia. The objective variables were the total MoCA, the MoCA subscale and the Mini-Mental State Examination (MMSE). Results There was a difference in the MoCA and MMSE scores between the 3 CDR groups. The MoCA score overlapped in participants with CDR 0 and 0.5. There were significant CDR effects, while there were no significant infarction effects for the MoCA and MMSE. vmSVD participants had lower scores on the total MoCA, the MoCA attention subscale and MMSE than healthy elderly people and participants with other types of dementia. Conclusion Our results suggested that MMSE performed rather well and that the MoCA is not superior to MMSE in MCI and vmSVD participants aged 75 and above in a community. PMID:23277783
A Java speech implementation of the Mini Mental Status Exam.
Wang, S. S.; Starren, J.
1999-01-01
The Folstein Mini Mental Status Exam (MMSE) is a simple, widely used, verbally administered test to assess cognitive function. The Java Speech Application Programming Interface (JSAPI) is a new, cross-platform interface for both speech recognition and speech synthesis in the Java environment. To evaluate the suitability of the JSAPI for interactive, patient interview applications, a JSAPI implementation of the MMSE was developed. The MMSE contains questions that vary in structure in order to assess different cognitive functions. This question variability provided an excellent test-bed to evaluate the strengths and weaknesses of JSAPI. The application is based on Java platform 2 and a JSAPI interface to the IBM ViaVoice recognition engine. Design and implementations issues are discussed. Preliminary usability studies demonstrate that an automated MMSE maybe a useful screening tool for cognitive disorders and changes. Images Figure 2 Figure 3 Figure 4 PMID:10566396
Adapting the mini mental status to the context of the West-Indies.
Godaert, Lidvine; Godard-Sebillotte, Claire; Bousquet, Lionel; Devouche, Emmanuel; Hugonot-Diener, Laurence; Nuissier, Joëlle; Triboulet, Frank; Fanon, Jean-Luc
2017-03-01
The mini mental state examination (MMSE) has become a benchmark for the screening and follow-up of cognitive impairment. The numerous translations of the MMS into other languages attest to its popularity. Clinical practice suggests that the consensual French version from the Greco (Groupe de réflexion sur les évaluations cognitives - Research working group for cognitive assessment) is not adapted to the West-Indies population because of the low socio-economic level and the widespread use of the Creole language among the elderly population. Modification of certain items by a multidisciplinary committee made it possible to adapt the instrument to the Creole culture. This procedure increases comprehension of the instrument, and should lead to improved detection of cognitive impairment in the West-Indies.
Fitzpatrick, A.Liam; Kaplan, Jared; /SLAC
2012-02-14
We show that suitably regulated multi-trace primary states in large N CFTs behave like 'in' and 'out' scattering states in the flat-space limit of AdS. Their transition matrix elements approach the exact scattering amplitudes for the bulk theory, providing a natural CFT definition of the flat space S-Matrix. We study corrections resulting from the AdS curvature and particle propagation far from the center of AdS, and show that AdS simply provides an IR regulator that disappears in the flat space limit.
Inseparability of photon-added Gaussian states
Li Hongrong; Li Fuli; Zhu Shiyao
2007-06-15
The inseparability of photon-added Gaussian states which are generated from two-mode Gaussian states by adding photons is investigated. According to the established inseparability conditions [New J. Phys. 7, 211 (2005); Phys. Rev. Lett. 96, 050503 (2006)], we find that even if a two-mode Gaussian state is separable, the photon-added Gaussian state becomes entangled when the purity of the Gaussian state is larger than a certain value. The lower bound of entanglement of symmetric photon-added Gaussian states is derived. The result shows that entanglement of the photon-added Gaussian states is involved with high-order moment correlations. We find that fidelity of teleporting coherent states cannot be raised by employing the photon-added Gaussian states as a quantum channel of teleportation.
Prediction of MCI to AD conversion, via MRI, CSF biomarkers, and pattern classification.
Davatzikos, Christos; Bhatt, Priyanka; Shaw, Leslie M; Batmanghelich, Kayhan N; Trojanowski, John Q
2011-12-01
Magnetic resonance imaging (MRI) patterns were examined together with cerebrospinal fluid (CSF) biomarkers in serial scans of Alzheimer's Disease Neuroimaging Initiative (ADNI) participants with mild cognitive impairment (MCI). The SPARE-AD score, summarizing brain atrophy patterns, was tested as a predictor of short-term conversion to Alzheimer's disease (AD). MCI individuals that converted to AD (MCI-C) had mostly positive baseline SPARE-AD (Spatial Pattern of Abnormalities for Recognition of Early AD) and atrophy in temporal lobe gray matter (GM) and white matter (WM), posterior cingulate/precuneous, and insula. MCI individuals that converted to AD had mostly AD-like baseline CSF biomarkers. MCI nonconverters (MCI-NC) had mixed baseline SPARE-AD and CSF values, suggesting that some MCI-NC subjects may later convert. Those MCI-NC with most negative baseline SPARE-AD scores (normal brain structure) had significantly higher baseline Mini Mental State Examination (MMSE) scores (28.67) than others, and relatively low annual rate of Mini Mental State Examination decrease (-0.25). MCI-NC with midlevel baseline SPARE-AD displayed faster annual rates of SPARE-AD increase (indicating progressing atrophy). SPARE-AD and CSF combination improved prediction over individual values. In summary, both SPARE-AD and CSF biomarkers showed high baseline sensitivity, however, many MCI-NC had abnormal baseline SPARE-AD and CSF biomarkers. Longer follow-up will elucidate the specificity of baseline measurements.
Noncommutative q -photon-added coherent states
NASA Astrophysics Data System (ADS)
Dey, Sanjib; Hussin, Véronique
2016-05-01
We construct the photon-added coherent states of a noncommutative harmonic oscillator associated to a q -deformed oscillator algebra. Various nonclassical properties of the corresponding system are explored, first, by studying two different types of higher-order quadrature squeezing, namely, the Hillery type and the Hong-Mandel type, and second, by testing the sub-Poissonian nature of photon statistics in higher order with the help of the correlation function and the Mandel parameter. Also, we compare the behavior of different types of quadrature and photon number squeezing of our system with those of the ordinary harmonic oscillator by considering the same set of parameters.
AD8 Informant Questionnaire for Cognitive Impairment: Pragmatic Diagnostic Test Accuracy Study.
Larner, A J
2015-09-01
The diagnostic accuracy of the AD8 informant questionnaire for cognitive impairment was assessed in patients referred to a dedicated memory clinic. This pragmatic prospective study of consecutive referrals attending with an informant who completed AD8 (n = 212) lasted 12 months. Diagnosis used standard clinical diagnostic criteria for dementia and mild cognitive impairment as reference standard (prevalence of cognitive impairment = 0.62). The AD8 proved acceptable to informants, was quick, and easy to use. Using the cutoff of ≥2/8, AD8 was highly sensitive (0.97) for diagnosis of cognitive impairment but specificity was poor (0.17). Combining AD8 with either the Mini-Mental State Examination or the Six-Item Cognitive Impairment Test showed little additional diagnostic benefit. In conclusion, AD8 is very sensitive for cognitive impairment in a memory clinic but specificity may be inadequate.
Photon-added coherent states in parametric down-conversion
Sivakumar, S.
2011-03-15
Photon-added coherent states have been realized in optical parametric down-conversion by Zavatta et al. [Science 306, 660 (2004)]. In this report, it is established that the states generated in the process are ideal photon-added coherent states. It is shown that the scheme can generate higher-order photon-added coherent states. A comparative study of the down-conversion process and atom-cavity interaction in generating the photon-added coherent states is presented.
2010-01-01
Background Diabetes is considered an independent risk factor for cognitive impairment and some studies observed through neuropsychological tests that cognitive disfunction affects both elderly and younger patients with diabetes. The aims of this study were to evaluate the cognitive status of outpatients with type 2 diabetes and to evaluate factors associated with impaired function. Methods A cross-sectional study was conducted in a group of type 2 diabetic outpatients. They were asked to undergo the Mini-Mental State Examination (MMSE) during routine ambulatory visits between April 2006 and January 2007, with the highest pontuation of the test being 30 points. Patients were classified as having possible dementia according to years of study. Exclusion criteria were blindness, illiterately, stroke, Alzheimer disease and psychiatric disorder. Results are presented as median (interquartile range) or mean ± SD. Results The study group was composed of 346 type 2 diabetic outpatients (216 females), aged 58,6 ± 12,1 years and with duration of diabetes of 12,3 ± 9,1 years. Hypertension was present in 77,2%. The total MMSE score achieved was 26 points (16 - 30) and was correlated with years of study (R2 = 0,39, p < 0,001) and 'per capita' income (R2 = 0,22, p < 0,0001) and duration of diabetes (R2 = - 0,13, p = 0,01). Patients who needed help to take their medications obtained worst performance in the MMSE (23,16 ± 3,55 vs 25,7 ± 2,84, p < 0,01) and were more likely to present possible dementia (p < 0,01). Forty two subjects (12.1%) had diagnosis of possible dementia and this was also associated with years of study (p = 0,045). No association was observed between possible dementia and total MMSE scores with A1C levels. Conclusions We conclude that patients with type 2 diabetes should be regularly evaluated for their cognitive function, because duration of disease could be associated with decline in cognition. The early implementation of mini mental which is a simple
Kang, In-Woong; Beom, In-Gyu; Cho, Ji-Yeon
2016-01-01
Background The Korean-Mini-Mental Status Examination (K-MMSE) is a dementia-screening test that can be easily applied in both community and clinical settings. However, in 20% to 30% of cases, the K-MMSE produces a false negative response. This suggests that it is necessary to evaluate the accuracy of K-MMSE as a screening test for dementia, which can be achieved through comparison of K-MMSE and Seoul Neuropsychological Screening Battery (SNSB)-II results. Methods The study included 713 subjects (male 534, female 179; mean age, 69.3±6.9 years). All subjects were assessed using K-MMSE and SNSB-II tests, the results of which were divided into normal and abnormal in 15 percentile standards. Results The sensitivity of the K-MMSE was 48.7%, with a specificity of 89.9%. The incidence of false positive and negative results totaled 10.1% and 51.2%, respectively. In addition, the positive predictive value of the K-MMSE was 87.1%, while the negative predictive value was 55.6%. The false-negative group showed cognitive impairments in regions of memory and executive function. Subsequently, in the false-positive group, subjects demonstrated reduced performance in memory recall, time orientation, attention, and calculation of K-MMSE items. Conclusion The results obtained in the study suggest that cognitive function might still be impaired even if an individual obtained a normal score on the K-MMSE. If the K-MMSE is combined with tests of memory or executive function, the accuracy of dementia diagnosis could be greatly improved. PMID:27274389
Bae, K; Bruner, D W; Baek, S; Movsas, B; Corn, B W; Dignam, J J
2011-11-01
The Mini Mental Status Exam (MMSE) instrument has been commonly used in the Radiation Therapy Oncology Group (RTOG) to assess mental status in brain cancer patients. Evaluating patient factors in relation to patterns of incomplete MMSE assessments can provide insight into predictors of missingness and optimal MMSE collection schedules in brain cancer clinical trials. This study examined eight RTOG brain cancer trials with ten treatment arms and 1,957 eligible patients. Patient data compliance patterns were categorized as: (1) evaluated at all time points (Complete), (2) not evaluated from a given time point or any subsequent time points but evaluated at all the previous time points (Monotone drop-out), (3) not evaluated at any time point (All missing), and (4) all other patterns (Mixed). Patient characteristics and reasons for missingness were summarized and compared among the missing pattern groups. Baseline MMSE scores and change scores after radiation therapy (RT) were compared between these groups, adjusting for differences in other characteristics. There were significant differences in frequency of missing patterns by age, treatment type, education, and Zubrod performance status (ZPS; P < 0.001). Ninety-two percent of patients were evaluated at least once: seven percent of patients were complete pattern, 49% were Monotone pattern, and 36% were mixed pattern. Patients who received RT only regimens were evaluated at a higher rate than patients who received RT + other treatments (49-64% vs. 27-45%). Institutional error and request to not be contacted were the most frequent known reasons for missing data, but most often, reasons for missing MMSE was unspecified. Differences in baseline mean MMSE scores by missing pattern (Complete, Monotone dropout, Mixed) were statistically significant (P < 0.001) but differences were small (<1.5 points) and significance did not persist after adjustment for age, ZPS, and other factors related to missingness. Post-RT change scores
Photon-added coherent states for the Morse oscillator
NASA Astrophysics Data System (ADS)
Popov, Dusan; Zaharie, Ioan; Dong, Shi-Hai
2006-02-01
In the paper we have constructed and investigated some properties of the Perelomov's “generalized coherent states” and photon-added coherent states for the Morse one-dimensional Hamiltonian (MO-PACSs), using the SU(2) group generators. We have found the integration measure in the resolution of unity and we have calculated some expectation values in the MO-PACSs representation. Using these states, the diagonal P-representation of the density operator is constructed as a new result for Morse potential. In addition, we have calculated some thermal expectation values for the quantum canonical diatomic gas of the Morse oscillators.
Item analysis of ADAS-Cog: effect of baseline cognitive impairment in a clinical AD trial.
Sevigny, Jeffrey J; Peng, Yahong; Liu, Lian; Lines, Christopher R
2010-03-01
We explored the association of Alzheimer's disease (AD) Assessment Scale (ADAS-Cog) item scores with AD severity using cross-sectional and longitudinal data from the same study. Post hoc analyses were performed using placebo data from a 12-month trial of patients with mild-to-moderate AD (N =281 randomized, N =209 completed). Baseline distributions of ADAS-Cog item scores by Mini-Mental State Examination (MMSE) score and Clinical Dementia Rating (CDR) sum of boxes score (measures of dementia severity) were estimated using local and nonparametric regressions. Mixed-effect models were used to characterize ADAS-Cog item score changes over time by dementia severity (MMSE: mild =21-26, moderate =14-20; global CDR: mild =0.5-1, moderate =2). In the cross-sectional analysis of baseline ADAS-Cog item scores, orientation was the most sensitive item to differentiate patients across levels of cognitive impairment. Several items showed a ceiling effect, particularly in milder AD. In the longitudinal analysis of change scores over 12 months, orientation was the only item with noticeable decline (8%-10%) in mild AD. Most items showed modest declines (5%-20%) in moderate AD.
Entanglement of Photon-Added Nonlinear Coherent States Via a Beam Splitter
NASA Astrophysics Data System (ADS)
Honarasa, Gholamreza; Bagheri, Alireza; Gharaati, Abdolrasoul
2016-10-01
Nonlinear coherent states, photon-added coherent states and photon-added nonlinear coherent states are three of the important generalizations of standard coherent states. In this article, a photon-added nonlinear coherent state and a vacuum state are injected on two input modes of a beam splitter and the entanglement of the output state is investigated using linear entropy as the measure. Then, the impact of nonclassicality of the photon-added nonlinear coherent state on entanglement of the output state is studied.
Non-Gaussianity of quantum states: An experimental test on single-photon-added coherent states
Barbieri, Marco; Ferreyrol, Franck; Blandino, Remi; Grangier, Philippe; Tualle-Brouri, Rosa; Spagnolo, Nicolo; Genoni, Marco G.; Paris, Matteo G. A.
2010-12-15
Non-Gaussian states and processes are useful resources in quantum information with continuous variables. An experimentally accessible criterion has been proposed to measure the degree of non-Gaussianity of quantum states based on the conditional entropy of the state with a Gaussian reference. Here we adopt such a criterion to characterize an important class of nonclassical states: single-photon-added coherent states. Our studies demonstrate the reliability and sensitivity of this measure and use it to quantify how detrimental is the role of experimental imperfections in our implementation.
Cubrovic, Mihailo; Liu Yan; Schalm, Koenraad; Sun Yawen; Zaanen, Jan
2011-10-15
We argue that the electron star and the anti-de Sitter (AdS) Dirac hair solution are two limits of the free charged Fermi gas in AdS. Spectral functions of holographic duals to probe fermions in the background of electron stars have a free parameter that quantifies the number of constituent fermions that make up the charge and energy density characterizing the electron star solution. The strict electron star limit takes this number to be infinite. The Dirac hair solution is the limit where this number is unity. This is evident in the behavior of the distribution of holographically dual Fermi surfaces. As we decrease the number of constituents in a fixed electron star background the number of Fermi surfaces also decreases. An improved holographic Fermi ground state should be a configuration that shares the qualitative properties of both limits.
Thajeb, Peterus; Thajeb, Teguh; Dai, Daofu
2007-03-01
Existing neuropsychological tests are often complex and time-consuming. We designed a modified Mini Mental Test (MMT) battery for clinical assessment of the global and regional higher cortical functions of the brain. We tested its applicability in healthy subjects with different ethnic, cultural and educational backgrounds. The usefulness of our MMT as a tool for the clinical evaluation of patients with various forms of vascular dementia was determined. The MMT comprises five subtests, including clinical evaluations of: (A) orientation (6 points); (B) attention, right-left discrimination, speech, and calculation (20); (C) immediate recall, and recent and remote memory retrieval (10); (D) praxis (10); and (E) visuospatial orientation, agnosia, hemianopsia, and visual hemineglect (14). The MMT was administered to 100 healthy subjects from two different ethnic backgrounds (Indonesian and Chinese/Taiwanese) and diverse cultural and educational backgrounds, and to 61 patients with various forms of vascular dementia. MMT scores were significantly lower in healthy subjects with a low level of education regardless of their ethnic background (p<0.001). Patients with vascular dementia had much lower MMT scores than did the comparable age-adjusted normal controls (p<0.001). Of the patients with vascular dementia, those with Binswanger's disease had the lowest MMT scores (25.5+/-28.9), followed by those with large cerebral infarcts (48.0+/-7.1), cerebral haemorrhage (49.0+/-8.5), and multiple lacunar infarctions (55.0+/-0.5) (P<0.001). With a cut-off point of 33/55 (partial score/total score), the sensitivity and positive predictive value of the MMT were 0.98 and 0.94, respectively. The MMT is a simple and useful tool for clinical assessment of the cognitive functions of healthy subjects and patients with or without vascular dementia. It can be used for individuals with different ethnic, cultural and educational backgrounds.
Spalletta, Gianfranco; Gianni, Walter; Giubilei, Franco; Casini, Anna R; Sancesario, Giuseppe; Caltagirone, Carlo; Cravello, Luca
2013-01-01
Here we investigated the effect of the rivastigmine patch alone on depression in 50 mild Alzheimer's disease (AD) patients with comorbid major depressive episode (MDE). First diagnosis acetyl-cholinesterase inhibitor and psychoactive drug-free outpatients (n=50) were recruited in memory clinics and reassessed after 3 and 6 months. Global cognitive functioning, depressive symptoms and MDE frequency were evaluated with the Mini Mental State Examination, the CERAD Dysphoria scale and the modified DSM-IV criteria for MDE in AD. MDE frequency reduced significantly from the first diagnostic visit (100%) to the 6-month follow-up (62%). We also found a significant reduction in CERAD Dysphoria scores that decreased from 6.2±3.9 mean±standard deviation to 4.9±4.5 at the 6-month follow-up. In AD patients with MDE rivastigmine alone can have a positive impact on depressive phenomena. Thus, future controlled study are justified to definitively verify if rivastigmine alone may improve depression in AD.
A Value-Added Estimate of Higher Education Quality of US States
ERIC Educational Resources Information Center
Zhang, Lei
2009-01-01
States differ substantially in higher education policies. Little is known about the effects of state policies on the performance of public colleges and universities, largely because no clear measures of college quality exist. In this paper, I estimate the average quality of public colleges of US states based on the value-added to individuals'…
Walking stabilizes cognitive functioning in Alzheimer's disease (AD) across one year.
Winchester, J; Dick, M B; Gillen, D; Reed, B; Miller, B; Tinklenberg, J; Mungas, D; Chui, H; Galasko, D; Hewett, L; Cotman, C W
2013-01-01
AD is a public health epidemic, which seriously impacts cognition, mood and daily activities; however, one type of activity, exercise, has been shown to alter these states. Accordingly, we sought to investigate the relationship between exercise and mood, in early-stage AD patients (N=104) from California, over a 1-year period. Patients completed the Mini-Mental State Examination (MMSE), Geriatric Depression Scale (GDS), and Blessed-Roth Dementia Rating Scale (BRDRS), while their caregivers completed the Yale Physical Activity Survey (YALE), Profile of Mood States (POMS), the Neuropsychiatric Inventory (NPI) and Functional Abilities Questionnaire (FAQ). Approximately half of the participants were female, from a variety of ethnic groups (Caucasian=69.8%; Latino/Hispanic Americans=20.1%). Our results demonstrated that the patients spent little time engaged in physical activity in general, their overall activity levels decreased over time, and this was paired with a change in global cognition (e.g., MMSE total score) and affect/mood (e.g., POMS score). Patients were parsed into Active and Sedentary groups based on their Yale profiles, with Active participants engaged in walking activities, weekly, over 1 year. Here, Sedentary patients had a significant decline in MMSE scores, while the Active patients had an attenuation in global cognitive decline. Importantly, among the Active AD patients, those individuals who engaged in walking for more than 2 h/week had a significant improvement in MMSE scores. Structured clinical trials which seek to increase the amount of time AD patients were engaged in walking activities and evaluate the nature and scope of beneficial effects in the brain are warranted.
Clinical utility of the informant AD8 as a dementia case finding instrument in primary healthcare.
Chan, Qun Lin; Xu, Xin; Shaik, Muhammad Amin; Chong, Steven Shih Tsze; Hui, Richard Jor Yeong; Chen, Christopher Li-Hsian; Dong, YanHong
2016-01-01
The informant AD8 has excellent discriminant ability for dementia case finding in tertiary healthcare settings. However, its clinical utility for dementia case finding at the forefront of dementia management, primary healthcare, is unknown. Therefore, we recruited participants from two primary healthcare centers in Singapore and measured their performance on the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Clinical Dementia Rating (CDR), and a local formal neuropsychological battery, in addition to the AD8. Logistic regression was conducted to examine the associations between demographic factors and dementia. Area under the receiver operating characteristics (ROC) curve analysis was used to establish the optimal cut-off points for dementia case finding. Of the 309 participants recruited, 243 (78.7%) had CDR = 0, 22 (7.1%) CDR = 0.5, and 44 (14.2%) CDR ≥1. Age was strongly associated with dementia, and the optimal age for dementia case finding in primary healthcare settings was ≥75 years. In this age group, the AD8 has excellent dementia case finding capability and was superior to the MMSE and equivalent to the MoCA [AD8 AUC (95% CI): 0.95 (0.91-0.99), cut-off: ≥3, sensitivity: 0.90, specificity: 0.88, PPV: 0.79 and NPV: 0.94; MMSE AUC (95% CI): 0.87 (0.79-0.94), p = 0.04; MoCA AUC (95% CI): 0.88 (0.82-0.95), p = 0.06]. In conclusion, the AD8 is well suited for dementia case finding in primary healthcare settings.
Saka, Esen; Dogan, Ebru Apaydin; Topcuoglu, Mehmet Akif; Senol, Utku; Balkan, Sevin
2007-01-01
Clinical discrimination of the early stages of AD and MCI is challenging. MRI indices which are simple enough to be applied by non-radiologists on hard copies would be of practical importance in the discrimination. We studied 45 consecutive patients (17 with MCI, 25 with AD, 3 with normal cognitive findings) with at least one white matter lesion (WML) on axial fluid-attenuated inversion recovery (FLAIR) MRI sequences. WML load was evaluated by Fazekas' scoring system; temporal lobe atrophy by interuncal distance (IUD) measurement. WML pattern had no significant discriminative value of AD and MCI. No significant correlation between periventricular/subcortical WML scores and neuropsychological test results was observed. The mean IUD was significantly smaller in patients with MCI compared to those with AD. The cut-off value of IUD was 28.3 mm with receiver operating curve (ROC) analysis. Area under the curve was 0.925 (95% CI: 0.800-0.983). A significant negative correlation between IUD and the mini mental state examination (MMSE), verbal fluency, clock drawing, and Rey Auditory verbal learning test (AVLT) was noted. The results indicate that measurement of IUD is a clinically useful test in discrimination of AD and MCI patients with WML(s) on brain MRI. However, severity of these lesions is not useful for distinctions.
Statistical Properties of Photon-Added Two-Mode Squeezed Coherent States
NASA Astrophysics Data System (ADS)
Wang, Zhen; Li, Heng-Mei; Yuan, Hong-Chun; Wan, Zhi-Long; Meng, Xiang-Guo
2017-03-01
The nonclassical and non-Gaussian quantum states—photon-added two-mode squeezed coherent states have been theoretically introduced by adding multiple photons to each mode of the two-mode squeezed coherent states. Starting from the new expression of two-mode squeezing operator in entangled states representation, the normalization factor is obtained, which is directly related to bivariate Hermite polynomials. The sub-Poissonian photon statistics, cross-correlation between two modes, partial negative Wigner function are observed, which fully reflect the nonclassicality of the target states. The negative Wigner function often display non-Gaussian distribution meanwhile. The investigations may provide experimentalists with some better references in quantum engineering.
Technology Transfer Automated Retrieval System (TEKTRAN)
Biochemical evidence of low vitamin B-12 status is common in seniors, but its clinical relevance is unclear. Vitamin B-12 deficiency can result in rapid, irreversible cognitive decline – a phenomenon that has been linked to high folate status. Our objective was to investigate the cognitive significa...
The Added Dimension. State and Land-Grant Universities Serving State and Local Government.
ERIC Educational Resources Information Center
Phillips, Ione
Responses to a survey of university public service programs of benefit to state and local governments were received from 70 individual campuses, and one systemwide office, representing 79 of the 133 NASULGC member institutions and 41 of the 50 states. The survey asked for (1) information on institutes of government and on technical service units…
Construction of photon-added spin coherent states and their statistical properties
Berrada, K.
2015-07-15
In the present work, we construct and investigate some properties of the photon-added spin coherent states (PA-SCSs). The Klauder’s minimal set of conditions required to obtain coherent states are discussed. We give the analytical form for the positive weight function in the resolution of unity. Finally, we examine the statistical properties of the PA-SCSs in terms of different parameters using the Mandel’s Q-parameter. All these quantities are expressed in terms of hypergeometric and Meijer G-functions, and so, the PA-SCSs are a new field of application for these functions.
High-dimensional quantum key distribution with the entangled single-photon-added coherent state
NASA Astrophysics Data System (ADS)
Wang, Yang; Bao, Wan-Su; Bao, Hai-Ze; Zhou, Chun; Jiang, Mu-Sheng; Li, Hong-Wei
2017-04-01
High-dimensional quantum key distribution (HD-QKD) can generate more secure bits for one detection event so that it can achieve long distance key distribution with a high secret key capacity. In this Letter, we present a decoy state HD-QKD scheme with the entangled single-photon-added coherent state (ESPACS) source. We present two tight formulas to estimate the single-photon fraction of postselected events and Eve's Holevo information and derive lower bounds on the secret key capacity and the secret key rate of our protocol. We also present finite-key analysis for our protocol by using the Chernoff bound. Our numerical results show that our protocol using one decoy state can perform better than that of previous HD-QKD protocol with the spontaneous parametric down conversion (SPDC) using two decoy states. Moreover, when considering finite resources, the advantage is more obvious.
Donepezil delays progression to AD in MCI subjects with depressive symptoms
Lu, P H.; Edland, S D.; Teng, E; Tingus, K; Petersen, R C.; Cummings, J L.
2009-01-01
of Mental Disorders, 4th edition; HAM-D = Hamilton Depression Rating Scale; MCI = mild cognitive impairment; MMSE = Mini-Mental State Examination; NINCDS-ADRDA = National Institute of Neurological and Communicative Disorders and Stroke–Alzheimer's Disease and Related Disorders Association. PMID:19528519
ERIC Educational Resources Information Center
Hutchison-Lupardus, Tammy R.; Hatfield, Timothy E.; Snyder, Jennifer E.
2012-01-01
This problem-based learning project addressed the need to improve the construction and implementation of value-added teacher evaluation policies and instruments. State officials are constructing value-added teacher evaluation models due to accountability initiatives, while ignoring the holes and problems in its implementation. The team's…
Examples of modern quantum sensing and metrology with new results on photon-added coherent states
NASA Astrophysics Data System (ADS)
Luine, Jerome; Singh, Anjali; Gard, Bryan; Olson, Jonathan
2016-02-01
Quantum sensing and metrology is the application of non-classical resources to the measurement of physical quantities with precision or accuracy beyond that allowed by classical physics. For many years non-classical resources such as atomic energy quantization, Josephson Effect, and Quantum Hall Effect have been used to define the fundamental units of time, voltage, and resistance, respectively. In recent years non-classical resources such as quantum squeezing and entanglement have been exploited to expand the range of physical phenomena measured with unprecedented precision or accuracy. We summarize some of the recent research on advanced quantum sensing and metrology and discuss our analyses of photon-added coherent states (PACS) of light. These analyses take into account imperfect photon addition and detection processes and show that PACS enable beyond-classical signal-to-noise ratio for photon counting even in cases where the probability of intended photon addition is 80%. We also show that there remains undiscovered fundamental properties of PACS related to their production and implementation.
NASA Astrophysics Data System (ADS)
Ren, Gang; Du, Jian-ming; Zhang, Wen-hai; Yu, Hai-jun
2017-02-01
We examine nonclassical properties of the quantum state generated by applying Hermite polynomials photon-added operator on the even/odd coherent state (HPECS/HPOCS). Explicit expressions for its nonclassical properties, such as quantum statistical properties and squeezing phenomenon, are obtained. It is interesting to find that the HPECS/HPOCS exhibits sub-Poissonian distribution, anti-bunching effects and negative values of the Wigner function. Thus, we confirm the HPPECS/HPPOCS is a new nonclassical state. Finally, we reveal that the HPPECS/HPPOCS is a novel intelligent state by its squeezing effects in position distribution and quadrature squeezing.
Ruan, Zhijun; Zhang, Yufan; Tu, Jin; Qin, Jingui; Li, Qianqian; Li, Zhen
2016-02-18
By adding just a small amount of commercially available oxygen-containing molecules (OCMs), organometallic precursors could be easily converted to CNTs with high yield and high quality through the solid-state pyrolysis (SSP) process, although only nanospheres were obtained under the same conditions without the presence of OCMs, providing a convenient approach for the preparation of CNTs.
15 CFR 400.16 - Exemption from state and local ad valorem taxation of tangible personal property.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 15 Commerce and Foreign Trade 2 2014-01-01 2014-01-01 false Exemption from state and local ad valorem taxation of tangible personal property. 400.16 Section 400.16 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) FOREIGN-TRADE ZONES BOARD, DEPARTMENT...
NASA Astrophysics Data System (ADS)
A, Karimi; M, K. Tavassoly
2016-04-01
In this paper, after a brief review on the entangled squeezed states, we produce a new class of the continuous-variable-type entangled states, namely, deformed photon-added entangled squeezed states. These states are obtained via the iterated action of the f-deformed creation operator A = f (n)a † on the entangled squeezed states. In the continuation, by studying the criteria such as the degree of entanglement, quantum polarization as well as sub-Poissonian photon statistics, the two-mode correlation function, one-mode and two-mode squeezing, we investigate the nonclassical behaviors of the introduced states in detail by choosing a particular f-deformation function. It is revealed that the above-mentioned physical properties can be affected and so may be tuned by justifying the excitation number, after choosing a nonlinearity function. Finally, to generate the introduced states, we propose a theoretical scheme using the nonlinear Jaynes-Cummings model.
Cultural Variation in Antismoking Video Ads between the United States, Taiwan, and China
ERIC Educational Resources Information Center
Wong, Tzu-Jung; King, Jessica L.; Pomeranz, Jamie L.
2016-01-01
Antitobacco advertisement components, including types of messages and advertising appeals, have not been evaluated among multinational groups. This study identified and compared the content of antismoking video ads across three countries. We reviewed 86 antismoking video advertisements for the following information: severity of the consequences of…
Zhang, Wen-feng; Shao, Hong-wei; Wu, Feng-lin; Xie, Xin; Li, Zhu-Ming; Bo, Hua-Ben; Shen, Han; Wang, Teng; Huang, Shu-lin
2016-01-01
Adoptive transfer of genetically-modified T cells is a promising approach for treatment of both human malignancies and viral infections. Due to its ability to efficiently infect lymphocytes, the chimeric adenovirus Ad5F35 is potentially useful as an immunotherapeutic for the genetic modification of T cells. In previous studies, it was found that the infection efficiency of Ad5F35 was significantly increased without enhanced expression of the viral receptor after T cell stimulation; however, little is known about the underlying mechanism. Nonetheless, cell physiology has long been thought to affect viral infection. Therefore, we aimed to uncover the physiologic changes responsible for the increased infection efficiency of Ad5F35 following T cell stimulation. Given the complexity of intracellular transport we analyzed viral binding, entry, and escape using a Jurkat T cell model and found that both cell membrane fluidity and endosomal escape of Ad5F35 were altered under different physiological states. This, in turn, resulted in differences in the amount of virus entering cells and reaching the cytoplasm. These results provide additional insight into the molecular mechanisms underlying Ad5F35 infection of T cells and consequently, will help further the clinical application of genetically-modified T cells for immunotherapy. PMID:26972139
ERIC Educational Resources Information Center
Orsini, Larry L.; Hudack, Lawrence R.; Zekan, Donald L.
1999-01-01
The value-added statement (VAS), relatively unknown in the United States, is used in financial reports by many European companies. Saint Bonaventure University (New York) has adapted a VAS to make it appropriate for not-for-profit universities by identifying stakeholder groups (students, faculty, administrators/support personnel, creditors, the…
Adding it Up: State Challenges for Increasing College Access and Success
ERIC Educational Resources Information Center
Jobs for the Future, 2007
2007-01-01
This report, comprised of key indicators and projections related to postsecondary attainment, is designed to help institutional, system, and state leaders advance a conversation about the need to increase college access and success for all students. The profiles included show that while states vary considerably in their current and expected…
Claudio, Babiloni; Claudio, Del Percio; Marina, Boccardi; Roberta, Lizio; Susanna, Lopez; Filippo, Carducci; Nicola, Marzano; Andrea, Soricelli; Raffaele, Ferri; Ivano, Triggiani Antonio; Annapaola, Prestia; Serenella, Salinari; Rasser Paul, E; Erol, Basar; Francesco, Famà; Flavio, Nobili; Görsev, Yener; Durusu, Emek-Savaş Derya; Gesualdo, Loreto; Ciro, Mundi; Thompson Paul, M; Rossini Paolo, M.; Frisoni Giovanni, B
2014-01-01
Occipital sources of resting state electroencephalographic (EEG) alpha rhythms are abnormal, at the group level, in patients with amnesic mild cognitive impairment (MCI) and Alzheimer’s disease (AD). Here we evaluated the hypothesis that amplitude of these occipital sources is related to neurodegeneration in occipital lobe as measured by magnetic resonance imaging (MRI). Resting-state eyes-closed EEG rhythms were recorded in 45 healthy elderly (Nold), 100 MCI, and 90 AD subjects. Neurodegeneration of occipital lobe was indexed by weighted averages of gray matter density (GMD), estimated from structural MRIs. EEG rhythms of interest were alpha 1 (8–10.5 Hz) and alpha 2 (10.5–13 Hz). EEG cortical sources were estimated by low resolution brain electromagnetic tomography (LORETA). Results showed a positive correlation between occipital GMD and amplitude of occipital alpha 1 sources in Nold, MCI and AD subjects as a whole group (r=0.3, p=0.000004, N=235). Furthermore, there was a positive correlation between amplitude of occipital alpha 1 sources and cognitive status as revealed by Mini Mental State Evaluation (MMSE) score across all subjects (r=0.38, p=0.000001, N=235). Finally, amplitude of occipital alpha 1 sources allowed a moderate classification of individual Nold and AD subjects (sensitivity: 87.8%; specificity: 66.7%; area under the Receiver Operating Characteristic (ROC) curve: 0.81). These results suggest that the amplitude of occipital sources of resting state alpha rhythms is related to AD neurodegeneration in occipital lobe along pathological aging. PMID:25442118
Reading Minds: Adding Value to Services at the State Library of New South Wales.
ERIC Educational Resources Information Center
Burgess, Kerrie; Lake, Therese
This paper discusses the Research and Evaluation Program at the State Library of New South Wales (Australia) and what it has revealed about clients' notions of value and relevance. An overview is provided of the services that have been developed in order to meet clients expectations, including reading room services and the development of the 3Tier…
NASA Astrophysics Data System (ADS)
Kumamoto, Soichiro; Okubo, Kazuya; Fujii, Toru
2016-01-01
The aim of this study was to show the influence of locational states of submicron fibers added into epoxy matrix on mechanical properties of modified plane-woven carbon fiber reinforced plastic (CFRP). To change the locational states of submicron fibers, two kinds of fabrication processes were applied in preparing specimen by hand lay-up method. Submicron fibers were simply added into epoxy resin with ethanol after they were stirred by a dispersion process using homogenizer to be located far from the interface between reinforcement and matrix. In contrast, submicron fibers were attached onto the carbon fibers by injecting from a spray nozzle accompanying with ethanol to be located near the interface, after they were tentatively contained in ethanol. The plain-woven CFRP plates were fabricated by hand lay-up method and cured at 80 degree-C for 1 hour and then at 150 degree-C for 3 hours. After curing, the plain-woven CFRP plates were cut into the dimension of specimen. Tensile shear strength and Mode-II fracture toughness of CFRP were determined by tensile lap-shear test and End-notched flexure(ENF) test, respectively. When submicron fibers were located far from the interface between carbon fibers and epoxy resin, tensile shear strength and Mode-II fracture toughness of CFRP were improved 30% and 18% compared with those of unmodified case. The improvement ratio in modified case was rather low (about few percentages) in the case where submicron fibers were located near the interface. The result suggested that crack propagation should be prevented when submicron fibers were existed far from the interface due to the effective stress state around the crack tip.
Li, Yueh-Fen; Nelson, Michael C; Chen, Po-Hsu; Graf, Joerg; Li, Yebo; Yu, Zhongtang
2015-01-01
The microbiomes involved in liquid anaerobic digestion process have been investigated extensively, but the microbiomes underpinning solid-state anaerobic digestion (SS-AD) are poorly understood. In this study, microbiome composition and temporal succession in batch SS-AD reactors, operated at mesophilic or thermophilic temperatures, were investigated using Illumina sequencing of 16S rRNA gene amplicons. A greater microbial richness and evenness were found in the mesophilic than in the thermophilic SS-AD reactors. Firmicutes accounted for 60 and 82 % of the total Bacteria in the mesophilic and in the thermophilic SS-AD reactors, respectively. The genus Methanothermobacter dominated the Archaea in the thermophilic SS-AD reactors, while Methanoculleus predominated in the mesophilic SS-AD reactors. Interestingly, the data suggest syntrophic acetate oxidation coupled with hydrogenotrophic methanogenesis as an important pathway for biogas production during the thermophilic SS-AD. Canonical correspondence analysis (CCA) showed that temperature was the most influential factor in shaping the microbiomes in the SS-AD reactors. Thermotogae showed strong positive correlation with operation temperature, while Fibrobacteres, Lentisphaerae, Spirochaetes, and Tenericutes were positively correlated with daily biogas yield. This study provided new insight into the microbiome that drives SS-AD process, and the findings may help advance understanding of the microbiome in SS-AD reactors and the design and operation of SS-AD systems.
NASA Astrophysics Data System (ADS)
Anninos, Dionysios; Li, Wei; Padi, Megha; Song, Wei; Strominger, Andrew
2009-03-01
Three dimensional topologically massive gravity (TMG) with a negative cosmological constant -l-2 and positive Newton constant G admits an AdS3 vacuum solution for any value of the graviton mass μ. These are all known to be perturbatively unstable except at the recently explored chiral point μl = 1. However we show herein that for every value of μl ≠ 3 there are two other (potentially stable) vacuum solutions given by SL(2,Bbb R) × U(1)-invariant warped AdS3 geometries, with a timelike or spacelike U(1) isometry. Critical behavior occurs at μl = 3, where the warping transitions from a stretching to a squashing, and there are a pair of warped solutions with a null U(1) isometry. For μl > 3, there are known warped black hole solutions which are asymptotic to warped AdS3. We show that these black holes are discrete quotients of warped AdS3 just as BTZ black holes are discrete quotients of ordinary AdS3. Moreover new solutions of this type, relevant to any theory with warped AdS3 solutions, are exhibited. Finally we note that the black hole thermodynamics is consistent with the hypothesis that, for μl > 3, the warped AdS3 ground state of TMG is holographically dual to a 2D boundary CFT with central charges c_R-formula and c_L-formula.
NASA Astrophysics Data System (ADS)
Song, Wei; Anninos, Dionysios; Li, Wei; Padi, Megha; Strominger, Andrew
2009-03-01
Three dimensional topologically massive gravity (TMG) with a negative cosmological constant -ell-2 and positive Newton constant G admits an AdS3 vacuum solution for any value of the graviton mass μ. These are all known to be perturbatively unstable except at the recently explored chiral point μell = 1. However we show herein that for every value of μell ≠ 3 there are two other (potentially stable) vacuum solutions given by SL(2,Bbb R) × U(1)-invariant warped AdS3 geometries, with a timelike or spacelike U(1) isometry. Critical behavior occurs at μell = 3, where the warping transitions from a stretching to a squashing, and there are a pair of warped solutions with a null U(1) isometry. For μell > 3, there are known warped black hole solutions which are asymptotic to warped AdS3. We show that these black holes are discrete quotients of warped AdS3 just as BTZ black holes are discrete quotients of ordinary AdS3. Moreover new solutions of this type, relevant to any theory with warped AdS3 solutions, are exhibited. Finally we note that the black hole thermodynamics is consistent with the hypothesis that, for μell > 3, the warped AdS3 ground state of TMG is holographically dual to a 2D boundary CFT with central charges c_R-formula and c_L-formula.
NASA Astrophysics Data System (ADS)
Callebaut, Nele; Gubser, Steven S.; Samberg, Andreas; Toldo, Chiara
2015-11-01
We study segmented strings in flat space and in AdS 3. In flat space, these well known classical motions describe strings which at any instant of time are piecewise linear. In AdS 3, the worldsheet is composed of faces each of which is a region bounded by null geodesics in an AdS 2 subspace of AdS 3. The time evolution can be described by specifying the null geodesic motion of kinks in the string at which two segments are joined. The outcome of collisions of kinks on the worldsheet can be worked out essentially using considerations of causality. We study several examples of closed segmented strings in AdS 3 and find an unexpected quasi-periodic behavior. We also work out a WKB analysis of quantum states of yo-yo strings in AdS 5 and find a logarithmic term reminiscent of the logarithmic twist of string states on the leading Regge trajectory.
NASA Astrophysics Data System (ADS)
Aeineh, N.; Tavassoly, M. K.
2015-08-01
In this paper, we investigate the higher-order nonclassical properties of a particular class of generalized coherent states namely the deformed photon-added nonlinear coherent states (DPACS) A†m |α, f, m>. To achieve this purpose we pay attention to higher-orders of squeezing (both Hillery- and Hong-Mandel-types), sub-Poissonian statistics and anti-bunching of the mentioned states with a well-known nonlinearity function. It is shown that for enough large values of field intensity (|α|2) for a fixed N (the order of squeezing) by increasing m (the order of excitation) the degree of squeezing evaluated by Hillery and Hong-Mandel approaches increases, while for a chosen fixed value of m, by increasing N for Hillery (Hong-Mandel) type of squeezing the strength of squeezing decreases (increases). Similarly, the degree of higher-order sub-Poissonian statistics (with fixed K) becomes lower when m increases, while (with fixed m) it gets greater values when the order of sub-Poissonian K increases. At last, higher-order anti-bunching of the DPACS is evaluated, by which we established that its (always) negative values increase with increasing m, α and l (the order of anti-bunching) individually, i.e. the degree of anti-bunching increases.
Khazaee, Ali; Ebrahimzadeh, Ata; Babajani-Feremi, Abbas
2017-03-30
Brain network alterations in patients with Alzheimer's disease (AD) has been the subject of much investigation, but the biological mechanisms underlying these alterations remain poorly understood. Here, we aim to identify the changes in brain networks in patients with AD and mild cognitive impairment (MCI), and provide an accurate algorithm for classification of these patients from healthy control subjects (HC) by using a graph theoretical approach and advanced machine learning methods. Multivariate Granger causality analysis was performed on resting-state functional magnetic resonance imaging (rs-fMRI) data of 34 AD, 89 MCI, and 45 HC to calculate various directed graph measures. The graph measures were used as the original feature set for the machine learning algorithm. Filter and wrapper feature selection methods were applied to the original feature set to select an optimal subset of features. An accuracy of 93.3% was achieved for classification of AD, MCI, and HC using the optimal features and the naïve Bayes classifier. We also performed a hub node analysis and found that the number of hubs in HC, MCI, and AD were 12, 10, and 9, respectively, suggesting that patients with AD experience disturbance of critical communication areas in their brain network as AD progresses. The findings of this study provide insight into the neurophysiological mechanisms underlying MCI and AD. The proposed classification method highlights the potential of directed graph measures of rs-fMRI data for identification of the early stage of AD.
Baum, Rachel; Amjad, Urooj; Luh, Jeanne; Bartram, Jamie
2015-11-01
National and sub-national governments develop and enforce regulations to ensure the delivery of safe drinking water in the United States (US) and countries worldwide. However, periodic contamination events, waterborne endemic illness and outbreaks of waterborne disease still occur, illustrating that delivery of safe drinking water is not guaranteed. In this study, we examined the potential added value of a preventive risk management approach, specifically, water safety plans (WSPs), in the US in order to improve drinking water quality. We undertook a comparative analysis between US drinking water regulations and WSP steps to analyze the similarities and differences between them, and identify how WSPs might complement drinking water regulations in the US. Findings show that US drinking water regulations and WSP steps were aligned in the areas of describing the water supply system and defining monitoring and controls. However, gaps exist between US drinking water regulations and WSPs in the areas of team procedures and training, internal risk assessment and prioritization, and management procedures and plans. The study contributes to understanding both required and voluntary drinking water management practices in the US and how implementing water safety plans could benefit water systems to improve drinking water quality and human health.
Marquette, Ian; Quesne, Christiane
2014-11-15
Type III multi-step rationally extended harmonic oscillator and radial harmonic oscillator potentials, characterized by a set of k integers m{sub 1}, m{sub 2}, ⋯, m{sub k}, such that m{sub 1} < m{sub 2} < ⋯ < m{sub k} with m{sub i} even (resp. odd) for i odd (resp. even), are considered. The state-adding and state-deleting approaches to these potentials in a supersymmetric quantum mechanical framework are combined to construct new ladder operators. The eigenstates of the Hamiltonians are shown to separate into m{sub k} + 1 infinite-dimensional unitary irreducible representations of the corresponding polynomial Heisenberg algebras. These ladder operators are then used to build a higher-order integral of motion for seven new infinite families of superintegrable two-dimensional systems separable in cartesian coordinates. The finite-dimensional unitary irreducible representations of the polynomial algebras of such systems are directly determined from the ladder operator action on the constituent one-dimensional Hamiltonian eigenstates and provide an algebraic derivation of the superintegrable systems whole spectrum including the level total degeneracies.
NASA Astrophysics Data System (ADS)
Anabalón, Andrés; Astefanesei, Dumitru; Choque, David
2016-11-01
We construct exact hairy AdS soliton solutions in Einstein-dilaton gravity theory. We examine their thermodynamic properties and discuss the role of these solutions for the existence of first order phase transitions for hairy black holes. The negative energy density associated to hairy AdS solitons can be interpreted as the Casimir energy that is generated in the dual filed theory when the fermions are antiperiodic on the compact coordinate.
Barry, Robert J; Clarke, Adam R; McCarthy, Rory; Selikowitz, Mark; MacDonald, Brett; Dupuy, Franca E
2012-03-01
The effect of a single oral dose of caffeine was examined in a randomised double-blind placebo-controlled repeated-measures cross-over study. Eighteen children with AD/HD, aged between 8 and 13 years, were individually age- and gender-matched with a control group. All children participated in two sessions, one week apart. Skin conductance level (SCL) from a 3 min eyes-closed epoch, commencing 30 min after ingestion of caffeine or placebo, was examined. Across conditions, mean SCL was lower in the AD/HD group than controls, confirming hypoarousal in AD/HD. Caffeine produced an increase in SCL, and this increase did not differ between the groups. However, arousal increases were dose-dependent in controls, but not in AD/HD. Rather, caffeine-induced arousal increases in the AD/HD group were positively related to their hyperactivity/impulsivity levels. This suggests an anomalous arousal mechanism in AD/HD functionally related to impairment in one symptom dimension.
Feb. 23, 2016: added letters to the state of Utah, the Ten Tribes Partnership, the Southern Ute Indian Tribe and the Ute Mountain Tribe about adding the Bonita Peak Mining District to the Superfund National Priorities List (NPL).
NASA Astrophysics Data System (ADS)
Quareni, Francesca; Moretti, Roberto; Piochi, Monica; Chiodini, Giovanni
2007-03-01
The last eruptive event at Mount Vesuvius occurred in 1944 A.D., ending a cycle of continuous eruptive activity started with the sub-Plinian event of 1631 A.D. The aim of this research is (1) to model the thermal evolution of the volcanic system from 1631 A.D. up to the present and (2) to investigate the possible process leading the volcano to the current state of quiescence. A finite element software is employed to solve the time-dependent energy equation and obtain the thermal field in the volcanic edifice and the surrounding medium. Volcanological, petrological, and geophysical constraints are used to define the crustal structure beneath the volcanic edifice, the magma supply system active since 1631 A.D., and the physico-chemical conditions of magma. Thermodynamic properties of magma and wall rocks have been evaluated from well-established thermo-chemical compilations and data from the literature. It is shown that heat transfer due to magma degassing is required in addition to the heat conduction in order to obtain transient depth-temperature fields consistent with geochemical observations, high crustal magnetization, and rigid behavior of the shallow crust as indicated by geophysical data. Surface data of carbon dioxide soil flux coming out from the Mount Vesuvius crater are taken to constrain such an additional heat flux. The agreement between modeled and measured temperatures at the crater since 1944 A.D. proves the consistency of the model. It is concluded that the present state of quiescence of Mount Vesuvius is mostly a consequence of the absence of magma supply from the deep reservoir into the shallower system. This allows the cooling of residual magma left within the volcanic conduit and the transition from continuous eruptive activity to the condition of conduit obstruction. In this scenario, the hydrothermal system may have developed subsequent to the cooling of the magma within the conduit. Our findings are a direct consequence of the high
Castellazzi, Gloria; Palesi, Fulvia; Casali, Stefano; Vitali, Paolo; Sinforiani, Elena; Wheeler-Kingshott, Claudia A M; D'Angelo, Egidio
2014-01-01
In resting state fMRI (rs-fMRI), only functional connectivity (FC) reductions in the default mode network (DMN) are normally reported as a biomarker for Alzheimer's disease (AD). In this investigation we have developed a comprehensive strategy to characterize the FC changes occurring in multiple networks and applied it in a pilot study of subjects with AD and Mild Cognitive Impairment (MCI), compared to healthy controls (HC). Resting state networks (RSNs) were studied in 14 AD (70 ± 6 years), 12 MCI (74 ± 6 years), and 16 HC (69 ± 5 years). RSN alterations were present in almost all the 15 recognized RSNs; overall, 474 voxels presented a reduced FC in MCI and 1244 in AD while 1627 voxels showed an increased FC in MCI and 1711 in AD. The RSNs were then ranked according to the magnitude and extension of FC changes (gFC), putting in evidence 6 RSNs with prominent changes: DMN, frontal cortical network (FCN), lateral visual network (LVN), basal ganglia network (BGN), cerebellar network (CBLN), and the anterior insula network (AIN). Nodes, or hubs, showing alterations common to more than one RSN were mostly localized within the prefrontal cortex and the mesial-temporal cortex. The cerebellum showed a unique behavior where voxels of decreased gFC were only found in AD while a significant gFC increase was only found in MCI. The gFC alterations showed strong correlations (p < 0.001) with psychological scores, in particular Mini-Mental State Examination (MMSE) and attention/memory tasks. In conclusion, this analysis revealed that the DMN was affected by remarkable FC increases, that FC alterations extended over several RSNs, that derangement of functional relationships between multiple areas occurred already in the early stages of dementia. These results warrant future work to verify whether these represent compensatory mechanisms that exploit a pre-existing neural reserve through plasticity, which evolve in a state of lack of connectivity between different networks with
... need sugar to function properly. Added sugars contribute zero nutrients but many added calories that can lead to extra pounds or even obesity, thereby reducing heart health. If you think of your daily calorie needs as a budget, you want to “spend” ...
ERIC Educational Resources Information Center
UCLA IDEA, 2012
2012-01-01
Value added measures (VAM) uses changes in student test scores to determine how much "value" an individual teacher has "added" to student growth during the school year. Some policymakers, school districts, and educational advocates have applauded VAM as a straightforward measure of teacher effectiveness: the better a teacher,…
2012-03-22
audio codec is best suited for MANETS. The MANET simulation environment is established using OPNET . Varying combinations of workloads are submitted...Appendix A. OPNET Simulation Setup .......................................................................... 69 A.1 Scenario Creation and Setup...6. OPNET Ad Hoc Node Wireless Suite Configuration ................................................. 44 7. OPNET OLSR Protocol Configuration
NASA Astrophysics Data System (ADS)
Berrada, K.; Abdel-Khalek, S.
2016-10-01
The degree of purity and nonclassical properties for a two-level system interacting with a photon-added squeezed thermal field (PASTF) are described in terms of the physical parameters involved in the whole system state with and without time-dependent coupling effect. Specially, we investigate the influence of the squeezed parameter and photon-added number on the behavior of the linear entropy and the Mandel's parameter. We find that for each value of the photon-added number, there exist critical value of the squeezed parameter for which the linear entropy is maximal and the statistical properties get farther from the trivial case. Moreover, we show that the presence of the time-dependent coupling effect may increase the periodicity time and lead to quench oscillations of the Mandel's parameter during the evolution. Finally, we exploit an interesting relationship between the linear entropy and the Mandel's parameter in terms of the physical parameters.
Boulet, Sheree L; Warner, Lee; Adamski, Alys; Smith, Ruben A; Burley, Kim; Grigorescu, Violanda
2016-06-01
As the prevalence of chronic conditions among women of reproductive age continues to rise, studies assessing the intersection of chronic disease and women's reproductive health status are increasingly needed. However, many data systems collect only limited information on women's reproductive health, thereby hampering the appraisal of risk and protective factors across the life span. One way to expand the study of women's health with minimal investment in time and resources is to integrate questions on reproductive health into existing surveillance systems. In 2013, previously validated questions on women's self-reported reproductive history, use of contraception, and infertility were added to the Behavioral Risk Factor Surveillance System (BRFSS) by seven states (Connecticut, Kentucky, Massachusetts, Mississippi, Ohio, Texas, and Utah); all female respondents aged 18-50 years were included in the pool of respondents for these state-added questions. Of 8691 women who completed the questions, 13.2% reported ever experiencing infertility and 59.8% of those at risk for unintended pregnancy reported using contraception at last intercourse. The information garnered from the state-added reproductive health questions can be augmented with the BRFSS core questions on health-related risk behaviors, chronic conditions, and use of preventive services. Expanding existing data collection systems with supplemental questions on women's reproductive health can provide important information on risk factors and outcomes that may not be available from other sources.
ERIC Educational Resources Information Center
Garcia, John A.
2012-01-01
This article builds upon the literature on immigrants and the vote by focusing on three legal and democratic principles: state versus national citizenship, dual domestic residency, and globalization/dual citizenship. It first delineates the discretion and powers that states can utilize to establish suffrage rights. The article next develops…
NASA Astrophysics Data System (ADS)
Tripathi, D.; Dey, T. K.
2015-06-01
Temperature dependence of the normal state electrical resistivity of polycrystalline MgB2 added with 0, 0.5, 1, 3 and 5 wt. % of (Bi, Pb)-2223 (Bi1.8Pb0.26Sr2Ca2Cu3O10+x) superconducting powder have been investigated in the light of two band approach based on π and σ bands of MgB2 superconductor. The scattering rates (γσ, γπ) and residual resistivity (ρ0σ,ρ0π) of each band are estimated for the investigated samples. Our observation for pure MgB2 shows much higher scattering rate in π bands, as compared to σ bands and hence indicates 'dirty' nature of the samples. However, the addition of 2223 in MgB2 is found to enhance the scattering rate in both bands, but the enhancement is more pronounced in π bands as compared to σ bands. Contribution of each individual band towards the total electrical conductivity of 2223 added MgB2 pellets are separated. Our analysis confirms that σ band contribution shows a small increase with 2223 addition and reaches nearly 89% for 5 wt. % 2223 added MgB2 polycrystalline pellets. The electron-phonon coupling constant (λ) of pure and 2223 added MgB2 pellets calculated using Mc-Millan expression is found to be nearly invariant with 2223 addition.
Zhou, Yuyang; Zhang, Qichun; Wang, Hong
2016-08-30
To enhance the performance of the tracking property , this paper presents a novel control algorithm for a class of linear dynamic stochastic systems with unmeasurable states, where the performance enhancement loop is established based on Kalman filter. Without changing the existing closed loop with the PI controller, the compensative controller is designed to minimize the variances of the tracking errors using the estimated states and the propagation of state variances. Moreover, the stability of the closed-loop systems has been analyzed in the mean-square sense. A simulated example is included to show the effectiveness of the presented control algorithm, where encouraging results have been obtained.
Raghavan, S S; Krusell, A; Krusell, J; Lyerla, T A; Kolodny, E H
1985-01-01
To clarify the relationship between hexosaminidase A (HEX A) activity and GM2-ganglioside hydrolysis in atypical clinical situations of HEX A deficiency, we have developed a simple method to assess GM2-ganglioside metabolism in cultured fibroblasts utilizing GM2 labeled with tritium in the sphingosine portion of the molecule. The radioactive lipid is added to the media of cultured skin fibroblasts, and after 10 days the cells are thoroughly washed, then harvested, and their lipid composition analyzed by HPLC. The degree of hydrolysis of the ingested GM2 is determined by comparing the amount of radioactive counts recovered in undegraded substrate with total cellular radioactivity. A deficiency in GM2-ganglioside hydrolysis was demonstrated in seven HEX A-deficient adults with neurological signs and in two healthy-appearing adolescents with older affected siblings. In each case, an analysis of endogenous monosialoganglioside composition revealed an increase in GM2-ganglioside, confirming the presence of a block in the metabolism of GM2. No defect in GM2-catabolism was found in four other healthy individuals with HEX A deficiency. This method of assay is especially helpful in the evaluation of atypical cases of HEX A deficiency for the definitive diagnosis of GM2-gangliosidosis. Images Fig. 1 PMID:2934978
NASA Astrophysics Data System (ADS)
Tanaka, Koichi; Han, Liang; Zhou, Xue; Anders, André
2015-08-01
Charge-state-resolved ion energy-time distributions of pulsed Cu arc plasma were obtained by using direct (time-dependent) acquisition of the ion detection signal from a commercial ion mass-per-charge and energy-per-charge analyzer. We find a shift of energies of Cu2+, Cu3+ and Cu4+ ions to lower values during the first few hundred microseconds after arc ignition, which is evidence for particle collisions in the plasma. The generation of Cu+ ions in the later part of the pulse, measured by the increase of Cu+ signal intensity and an associated slight reduction of the mean charge state, points to charge exchange reactions between ions and neutrals. At the very beginning of the pulse, when the plasma expands into vacuum and the plasma potential strongly fluctuates, ions with much higher energy (over 200 eV) are observed. Early in the pulse, the ion energies observed are approximately proportional to the ion charge state, and we conclude that the acceleration mechanism is primarily based on acceleration in an electric field. This field is directed away from the cathode, indicative of a potential hump. Measurements by a floating probe suggest that potential structures travel, and ions moving in the traveling field can gain high energies up to a few hundred electron-volts. Later in the pulse, the approximate proportionality is lost, which is related to increased smearing out of different energies due to collisions with neutrals, and/or to a change of the acceleration character from electrostatic to ‘gas-dynamic’, i.e. dominated by pressure gradient.
ERIC Educational Resources Information Center
Wilson, M. Roy
2015-01-01
With more than a thousand honors programs or colleges in the United States and that number growing every year, defining the value of honors is a significant undertaking. Honors seems to have become an obligatory upgrade that no college or university president can afford to be without, but there is more than institutional trending to be considered,…
2011-09-01
of legal analysis, or “ IRAC ” (Lawnerds.com). IRAC involves the definition of the legal issue in question, a detailed review of the current legal...conclusions on how the law should judge the facts of the case in light of the issue. In this case, IRAC is used to: first, identify the legal and...global, non-state terror groups. 9 III. LEGAL ISSUE DEFINED To employ IRAC effectively in examining this paper’s overarching problem, it is
Action growth for AdS black holes
NASA Astrophysics Data System (ADS)
Cai, Rong-Gen; Ruan, Shan-Ming; Wang, Shao-Jiang; Yang, Run-Qiu; Peng, Rong-Hui
2016-09-01
Recently a Complexity-Action (CA) duality conjecture has been proposed, which relates the quantum complexity of a holographic boundary state to the action of a Wheeler-DeWitt (WDW) patch in the anti-de Sitter (AdS) bulk. In this paper we further investigate the duality conjecture for stationary AdS black holes and derive some exact results for the growth rate of action within the Wheeler-DeWitt (WDW) patch at late time approximation, which is supposed to be dual to the growth rate of quantum complexity of holographic state. Based on the results from the general D-dimensional Reissner-Nordström (RN)-AdS black hole, rotating/charged Bañados-Teitelboim-Zanelli (BTZ) black hole, Kerr-AdS black hole and charged Gauss-Bonnet-AdS black hole, we present a universal formula for the action growth expressed in terms of some thermodynamical quantities associated with the outer and inner horizons of the AdS black holes. And we leave the conjecture unchanged that the stationary AdS black hole in Einstein gravity is the fastest computer in nature.
Constructing the AdS dual of a Fermi liquid: AdS black holes with Dirac hair
NASA Astrophysics Data System (ADS)
Čubrović, Mihailo; Zaanen, Jan; Schalm, Koenraad
2011-10-01
We provide evidence that the holographic dual to a strongly coupled charged Fermi liquid has a non-zero fermion density in the bulk. We show that the pole-strength of the stable quasiparticle characterizing the Fermi surface is encoded in the AdS probability density of a single normalizable fermion wavefunction in AdS. Recalling Migdal's theorem which relates the pole strength to the Fermi-Dirac characteristic discontinuity in the number density at ω F , we conclude that the AdS dual of a Fermi liquid is described by occupied on-shell fermionic modes in AdS. Encoding the occupied levels in the total spatially averaged probability density of the fermion field directly, we show that an AdS Reissner-Nordström black holein a theory with charged fermions has a critical temperature, at which the system undergoes a first-order transition to a black hole with a non-vanishing profile for the bulk fermion field. Thermodynamics and spectral analysis support that the solution with non-zero AdS fermion-profile is the preferred ground state at low temperatures.
Orientifolded locally AdS3 geometries
NASA Astrophysics Data System (ADS)
Loran, F.; Sheikh-Jabbari, M. M.
2011-01-01
Continuing the analysis of [Loran F and Sheikh-Jabbari M M 2010 Phys. Lett. B 693 184-7], we classify all locally AdS3 stationary axi-symmetric unorientable solutions to AdS3 Einstein gravity and show that they are obtained by applying certain orientifold projection on AdS3, BTZ or AdS3 self-dual orbifold, respectively, O-AdS3, O-BTZ and O-SDO geometries. Depending on the orientifold fixed surface, the O-surface, which is either a space-like 2D plane or a cylinder, or a light-like 2D plane or a cylinder, one can distinguish four distinct cases. For the space-like orientifold plane or cylinder cases, these geometries solve AdS3 Einstein equations and are hence locally AdS3 everywhere except at the O-surface, where there is a delta-function source. For the light-like cases, the geometry is a solution to Einstein equations even at the O-surface. We discuss the causal structure for static, extremal and general rotating O-BTZ and O-SDO cases as well as the geodesic motion on these geometries. We also discuss orientifolding Poincaré patch AdS3 and AdS2 geometries as a way to geodesic completion of these spaces and comment on the 2D CFT dual to the O-geometries.
Solutions of free higher spins in AdS
NASA Astrophysics Data System (ADS)
Lü, H.; Shao, Kai-Nan
2011-11-01
We consider free massive and massless higher integer spins in AdS backgrounds in general D dimensions. We obtain the solutions corresponding to the highest-weight state of the spin-ℓ representations of the SO (2 , D - 1) isometry groups. The solution for the spin-ℓ field is expressed recursively in terms of that for the spin- (ℓ - 1). Thus starting from the explicit spin-0, all the higher-spin solutions can be obtained. These solutions allow us to derive the generalized Breitenlohner-Freedman bound, and analyze the asymptotic falloffs. In particular, solutions with negative mass square in general have falloffs slower than those of the Schwarzschild AdS black holes in the AdS boundaries.
Vansia, Dhrutika; Stephenson, Rob
2016-01-01
Background Gay, bisexual, and other men who have sex with men (MSM) regularly experience homophobic discrimination and stigma. While previous research has examined homophobic and HIV-related intergroup stigma originating from non-MSM directed at MSM, less is known about intragroup stigma originating from within MSM communities. While some research has examined intragroup stigma, this research has focused mostly on HIV-related stigma. Intragroup stigma may have a unique influence on sexual risk-taking behaviors as it occurs between sexual partners. Online sexual networking venues provide a unique opportunity to examine this type of stigma. Objective The purpose of this study is to examine the presence and patterns of various types of intragroup stigma represented in Men Seeking Men Craigslist sex ads. Methods Data were collected from ads on Craigslist sites from 11 of the 12 US metropolitan statistical areas with the highest HIV/AIDS prevalence. Two categories of data were collected: self-reported characteristics of the authors and reported biases in the ads. Chi-square tests were used to examine patterns of biases across cities and author characteristics. Results Biases were rarely reported in the ads. The most commonly reported biases were against men who were not “disease and drug free (DDF),” representing stigma against men living with HIV or a sexually transmitted infection. Patterns in bias reporting occurred across cities and author characteristics. There were no variations based on race, but ageism (mostly against older men) varied based on the ad author’s age and self-reported DDF status; bias against feminine gender expression varied based on self-reported sexual orientation; bias against “fat” men varied by self-reported DDF status; bias against “ugly” men varied by a self-report of being good-looking; and bias against people who do not have a DDF status varied based on self-reported HIV status and self-reported DDF status. Conclusions
NASA Astrophysics Data System (ADS)
Morales, Jose F.; Samtleben, Henning
2003-06-01
We review recent work on the holographic duals of type II and heterotic matrix string theories described by warped AdS3 supergravities. In particular, we compute the spectra of Kaluza-Klein primaries for type I, II supergravities on warped AdS3 × S7 and match them with the primary operators in the dual two-dimensional gauge theories. The presence of non-trivial warp factors and dilaton profiles requires a modification of the familiar dictionary between masses and 'scaling' dimensions of fields and operators. We present these modifications for the general case of domain wall/QFT correspondences between supergravities on warped AdSd+1 × Sq geometries and super Yang-Mills theories with 16 supercharges.
Lorentzian AdS geometries, wormholes, and holography
Arias, Raul E.; Silva, Guillermo A.; Botta Cantcheff, Marcelo
2011-03-15
We investigate the structure of two-point functions for the quantum field theory dual to an asymptotically Lorentzian Anti de Sitter (AdS) wormhole. The bulk geometry is a solution of five-dimensional second-order Einstein-Gauss-Bonnet gravity and causally connects two asymptotically AdS spacetimes. We revisit the Gubser-Klebanov-Polyakov-Witten prescription for computing two-point correlation functions for dual quantum field theories operators O in Lorentzian signature and we propose to express the bulk fields in terms of the independent boundary values {phi}{sub 0}{sup {+-}} at each of the two asymptotic AdS regions; along the way we exhibit how the ambiguity of normalizable modes in the bulk, related to initial and final states, show up in the computations. The independent boundary values are interpreted as sources for dual operators O{sup {+-}} and we argue that, apart from the possibility of entanglement, there exists a coupling between the degrees of freedom living at each boundary. The AdS{sub 1+1} geometry is also discussed in view of its similar boundary structure. Based on the analysis, we propose a very simple geometric criterion to distinguish coupling from entanglement effects among two sets of degrees of freedom associated with each of the disconnected parts of the boundary.
From path integrals to tensor networks for the AdS /CFT correspondence
NASA Astrophysics Data System (ADS)
Miyaji, Masamichi; Takayanagi, Tadashi; Watanabe, Kento
2017-03-01
In this paper, we discuss tensor network descriptions of AdS /CFT from two different viewpoints. First, we start with a Euclidean path-integral computation of ground state wave functions with a UV cutoff. We consider its efficient optimization by making its UV cutoff position dependent and define a quantum state at each length scale. We conjecture that this path integral corresponds to a time slice of anti-de Sitter (AdS) spacetime. Next, we derive a flow of quantum states by rewriting the action of Killing vectors of AdS3 in terms of the dual two-dimensional conformal field theory (CFT). Both approaches support a correspondence between the hyperbolic time slice H2 in AdS3 and a version of continuous multiscale entanglement renormalization ansatz. We also give a heuristic argument about why we can expect a sub-AdS scale bulk locality for holographic CFTs.
Hereford, R.
2002-01-01
Valley-fill alluvium deposited from ca. A.D. 1400 to 1880 is widespread in tributaries of the Paria River and is largely coincident with the Little Ice Age epoch of global climate variability. Previous work showed that alluvium of this age is a mappable stratigraphic unit in many of the larger alluvial valleys of the southern Colorado Plateau. The alluvium is bounded by two disconformities resulting from prehistoric and historic arroyo cutting at ca. A.D. 1200-1400 and 1860-1910, respectively. The fill forms a terrace in the axial valleys of major through-flowing streams. This terrace and underlying deposits are continuous and interfinger with sediment in numerous small tributary valleys that head at the base of hillslopes of sparsely vegetated, weakly consolidated bedrock, suggesting that eroded bedrock was an important source of alluvium along with in-channel and other sources. Paleoclimatic and high-resolution paleoflood studies indicate that valley-fill alluviation occured during a long-term decrease in the frequency of large, destructive floods. Aggradation of the valleys ended about A.D. 1880, if not two decades earlier, with the beginning of historic arroyo cutting. This shift from deposition to valley entrenchment near the close of the Little Ice Age generally coincided with the beginning of an episode of the largest floods in the preceding 400-500 yr, which was probably caused by an increased recurrence and intensity of flood-producing El Nin??o events beginning at ca. A.D. 1870.
Static Einstein-Maxwell Black Holes with No Spatial Isometries in AdS Space.
Herdeiro, Carlos A R; Radu, Eugen
2016-11-25
We explicitly construct static black hole solutions to the fully nonlinear, D=4, Einstein-Maxwell-anti-de Sitter (AdS) equations that have no continuous spatial symmetries. These black holes have a smooth, topologically spherical horizon (section), but without isometries, and approach, asymptotically, global AdS spacetime. They are interpreted as bound states of a horizon with the Einstein-Maxwell-AdS solitons recently discovered, for appropriate boundary data. In sharp contrast to the uniqueness results for a Minkowski electrovacuum, the existence of these black holes shows that single, equilibrium, black hole solutions in an AdS electrovacuum admit an arbitrary multipole structure.
On information loss in AdS3/CFT2
Fitzpatrick, A. Liam; Kaplan, Jared; Li, Daliang; ...
2016-05-18
We discuss information loss from black hole physics in AdS3, focusing on two sharp signatures infecting CFT2 correlators at large central charge c: ‘forbidden singularities’ arising from Euclidean-time periodicity due to the effective Hawking temperature, and late-time exponential decay in the Lorentzian region. We study an infinite class of examples where forbidden singularities can be resolved by non-perturbative effects at finite c, and we show that the resolution has certain universal features that also apply in the general case. Analytically continuing to the Lorentzian regime, we find that the non-perturbative effects that resolve forbidden singularities qualitatively change the behavior ofmore » correlators at times t ~SBH, the black hole entropy. This may resolve the exponential decay of correlators at late times in black hole backgrounds. By Borel resumming the 1/c expansion of exact examples, we explicitly identify ‘information-restoring’ effects from heavy states that should correspond to classical solutions in AdS3. Lastly, our results suggest a line of inquiry towards a more precise formulation of the gravitational path integral in AdS3.« less
NASA Astrophysics Data System (ADS)
Hertog, Thomas
2004-12-01
We review some properties of N=8 gauged supergravity in four dimensions with modified, but AdS invariant boundary conditions on the m2 = -2 scalars. There is a one-parameter class of asymptotic conditions on these fields and the metric components, for which the full AdS symmetry group is preserved. The generators of the asymptotic symmetries are finite, but acquire a contribution from the scalar fields. For a large class of such boundary conditions, we find there exist black holes with scalar hair that are specified by a single conserved charge. Since Schwarschild-AdS is a solution too for all boundary conditions, this provides an example of black hole non-uniqueness. We also show there exist solutions where smooth initial data evolve to a big crunch singularity. This opens up the possibility of using the dual conformal field theory to obtain a fully quantum description of the cosmological singularity, and we report on a preliminary study of this.
Freivogel, Ben; Hubeny, Veronika E.; Maloney, Alexander; Myers, Rob; Rangamani, Mukund; Shenker, Stephen; /Stanford U., Phys. Dept.
2005-10-07
We study the realization of inflation within the AdS/CFT correspondence. We assume the existence of a string landscape containing at least one stable AdS vacuum and a (nearby) metastable de Sitter state. Standard arguments imply that the bulk physics in the vicinity of the AdS minimum is described by a boundary CFT. We argue that large enough bubbles of the dS phase, including those able to inflate, are described by mixed states in the CFT. Inflating degrees of freedom are traced over and do not appear explicitly in the boundary description. They nevertheless leave a distinct imprint on the mixed state. Analytic continuation allows us, in principle, to recover a large amount of nonperturbatively defined information about the inflating regime. Our work also shows that no scattering process can create an inflating region, even by quantum tunneling, since a pure state can never evolve into a mixed state under unitary evolution.We study the realization of inflation within the AdS/CFT correspondence. We assume the existence of a string landscape containing at least one stable AdS vacuum and a (nearby) metastable de Sitter state. Standard arguments imply that the bulk physics in the vicinity of the AdS minimum is described by a boundary CFT. We argue that large enough bubbles of the dS phase, including those able to inflate, are described by mixed states in the CFT. Inflating degrees of freedom are traced over and do not appear explicitly in the boundary description. They nevertheless leave a distinct imprint on the mixed state. Analytic continuation allows us, in principle, to recover a large amount of nonperturbatively defined information about the inflating regime. Our work also shows that no scattering process can create an inflating region, even by quantum tunneling, since a pure state can never evolve into a mixed state under unitary evolution.
Ben Salem, M. K.; Slimani, Y.; Hannachi, E.; Hamrita, A.; Ben Azzouz, F.; Ben Salem, M.
2013-12-16
The effect of nano-sized CoFe{sub 2}O{sub 4} particles (10 nm in diameter) addition on the structure and the normal state transport properties of polycrystalline Bi-based superconductors were systematically studied. The additional amount, x wt.%, of CoFe{sub 2}O{sub 4} in this case varied from 0.0 to 1 wt.% of the total mass of the sample. Phase analysis by X-ray diffraction (XRD) and Electrical resistance as a function of temperature, ρ(T) were carried out. Nano-sized particles addition modifies the electrical behavior of the normal state with increasing the CoFe{sub 2}O{sub 4} concentration. The bipolaron model can explain properly the normal state resistivity of the samples.
Strings on AdS wormholes and nonsingular black holes
NASA Astrophysics Data System (ADS)
Lü, H.; Vázquez-Poritz, Justin F.; Zhang, Zhibai
2015-01-01
Certain AdS black holes in the STU model can be conformally scaled to wormhole and black hole backgrounds which have two asymptotically AdS regions and are completely free of curvature singularities. While there is a delta-function source for the dilaton, classical string probes are not sensitive to this singularity. According to the AdS/CFT correspondence, the dual field theory lives on the union of the disjoint boundaries. For the wormhole background, causal contact exists between the two boundaries and the structure of certain correlation functions is indicative of an interacting phase for which there is a coupling between the degrees of freedom living at each boundary. The nonsingular black hole describes an entangled state in two non-interacting identical conformal field theories. By studying the behavior of open strings on these backgrounds, we extract a number of features of the ‘quarks’ and ‘anti-quarks’ that live in the field theories. In the interacting phase, we find that there is a maximum speed with which the quarks can move without losing energy, beyond which energy is transferred from a quark in one field theory to a quark in the other. We also compute the rate at which moving quarks within entangled states lose energy to the two surrounding plasmas. While a quark-antiquark pair within a single field theory exhibits Coulomb interaction for small separation, a quark in one field theory exhibits spring-like confinement with an anti-quark in the other field theory. For the entangled states, we study how the quark-antiquark screening length depends on temperature and chemical potential.
ERIC Educational Resources Information Center
Guarino, Cassandra M.
2013-01-01
The push for accountability in public schooling has extended to the measurement of teacher performance, accelerated by federal efforts through Race to the Top. Currently, a large number of states and districts across the country are computing measures of teacher performance based on the standardized test scores of their students and using them in…
ERIC Educational Resources Information Center
New York State Interdepartmental Fuel and Energy Committee, Albany.
After presenting the background of the availability of fuel for transportation and the increasing per capita energy consumption, the report examines the State's role in energy conservation. Five proposals are outlined: (1) a coordinated education program designed to increase public awareness of the current energy situation; (2) a pilot program of…
ERIC Educational Resources Information Center
New York State Interdepartmental Fuel and Energy Committee, Albany.
High and wasteful energy consumption practices have become a part of the American life style. The United States, with six percent of the world's population, is responsible for 33 percent of the world's energy consumption. Americans are now faced with shortages of primary fuels, especially natural gas and oil, and with stringency of electric power…
NASA Astrophysics Data System (ADS)
Bena, Iosif; Heurtier, Lucien; Puhm, Andrea
2016-05-01
It was argued in [1] that the five-dimensional near-horizon extremal Kerr (NHEK) geometry can be embedded in String Theory as the infrared region of an infinite family of non-supersymmetric geometries that have D1, D5, momentum and KK monopole charges. We show that there exists a method to embed these geometries into asymptotically- {AdS}_3× {S}^3/{{Z}}_N solutions, and hence to obtain infinite families of flows whose infrared is NHEK. This indicates that the CFT dual to the NHEK geometry is the IR fixed point of a Renormalization Group flow from a known local UV CFT and opens the door to its explicit construction.
1988-02-01
provided a source of food and water. Army explorers, Capt. Meriwether Lewis and Lt. William Clark, led an expedition up the Missouri River. They crossed...maintain canals under county government supervision. The gold rushes in California in 1849 and in Colorado in 1856 contributed to a significant increase...E FIRMS 9. Ft. Sill, OK 10. McAlester AAP, OK CORPS OF ENGINEERS 11. Navajo Depot Activity, AZ USFS USFS COE State & MACOM County Health Dept. 12
NASA Astrophysics Data System (ADS)
Cvetič, Mirjam; Papadimitriou, Ioannis
2016-12-01
We construct the holographic dictionary for both running and constant dilaton solutions of the two dimensional Einstein-Maxwell-Dilaton theory that is obtained by a circle reduction from Einstein-Hilbert gravity with negative cosmological constant in three dimensions. This specific model ensures that the dual theory has a well defined ultraviolet completion in terms of a two dimensional conformal field theory, but our results apply qualitatively to a wider class of two dimensional dilaton gravity theories. For each type of solutions we perform holographic renormalization, compute the exact renormalized one-point functions in the presence of arbitrary sources, and derive the asymptotic symmetries and the corresponding conserved charges. In both cases we find that the scalar operator dual to the dilaton plays a crucial role in the description of the dynamics. Its source gives rise to a matter conformal anomaly for the running dilaton solutions, while its expectation value is the only non trivial observable for constant dilaton solutions. The role of this operator has been largely overlooked in the literature. We further show that the only non trivial conserved charges for running dilaton solutions are the mass and the electric charge, while for constant dilaton solutions only the electric charge is non zero. However, by uplifting the solutions to three dimensions we show that constant dilaton solutions can support non trivial extended symmetry algebras, including the one found by Compère, Song and Strominger [1], in agreement with the results of Castro and Song [2]. Finally, we demonstrate that any solution of this specific dilaton gravity model can be uplifted to a family of asymptotically AdS2 × S 2 or conformally AdS2 × S 2 solutions of the STU model in four dimensions, including non extremal black holes. The four dimensional solutions obtained by uplifting the running dilaton solutions coincide with the so called `subtracted geometries', while those obtained
Moftah, Omar Ali Saied; Grbavčić, Sanja; Zuža, Milena; Luković, Nevena; Bezbradica, Dejan; Knežević-Jugović, Zorica
2012-01-01
Olive oil cake is a by-product from the olive oil processing industry and can be used for the lipase and protease production by Candida utilis in solid state fermentation. Different carbon and nitrogen sources were evaluated, and the results showed that the supplementation of the substrate with maltose and starch as carbon sources and yeast extract as a nitrogen source significantly increased the lipase production. The best results were obtained with maltose, whereas rather low lipase and protease activities were found with glucose and oleic acid. Response surface methodology and a five-level-three-factor central composite rotatable design were used to evaluate the effects of the initial moisture content, inoculum size and fermentation time on both lipase and protease activity levels. A lipase activity value of ≈25 U g(-1) and a protease activity value of 110 U g(-1) were obtained under the optimized fermentation conditions. An alkaline treatment of the substrate appeared to be efficient, leading to increases of 39% and 133% in the lipase and protease production, respectively. The results showed that the olive cake could be a good source for enzyme production by solid state fermentation.
Shah, Romina; Kolanos, Renata; DiNovi, Michael J; Mattia, Antonia; Kaneko, Kotaro J
2017-03-27
Dietary exposure assessment using food consumption data and ingredient use level is essential for assessing safety of food ingredients. Dietary exposure estimates are compared to safe intake levels, such as Acceptable Daily Intake (ADI). ADI is estimated by applying a safety factor to an experimentally determined no-observed-adverse-effect-level of a test substance. Two food ingredients classified as emulsifiers, sodium carboxymethylcellulose (CMC) and polysorbate 80 (P80), received attention recently due to their putative adverse effects on gut microbiota. Because no published dietary exposure estimates for commonly used emulsifiers exist for the United States population, the current investigation focused on the estimation of dietary exposure to seven emulsifiers: CMC, P80, lecithin, mono- and diglycerides (MDG), stearoyl lactylates, sucrose esters, and polyglycerol polyricinoleate. Using maximum use levels obtained from publicly available sources, dietary exposures to these emulsifiers were estimated for the United States population (aged 2 years and older) for two time periods (1999-2002 and 2003-2010) using one- and two-day food consumption data from the National Health and Nutrition Examination Survey, and 10-14 day food consumption data from NPD Group, Inc. National Eating Trends-Nutrient Intake Database. Our analyses indicated that among the emulsifiers assessed, lecithin and MDG have the highest mean exposures at ~60 and ~80 mg/kg bw/day, respectively, whereas the exposure to CMC is one-half to one-third of lecithin or MDG; and the exposure to P80 is approximately one-half of CMC. The review of available safety information such as ADIs established by the Joint FAO/WHO Expert Committee on Food Additives, in light of our updated dietary exposure estimates for these seven emulsifiers, did not raise safety concerns at the current specified levels of use. Additionally, by examining two time periods (1999-2002) and (2003-2010), it was concluded that there is no
Primordial fluctuations from complex AdS saddle points
Hertog, Thomas; Woerd, Ellen van der E-mail: ellen@itf.fys.kuleuven.be
2016-02-01
One proposal for dS/CFT is that the Hartle-Hawking (HH) wave function in the large volume limit is equal to the partition function of a Euclidean CFT deformed by various operators. All saddle points defining the semiclassical HH wave function in cosmology have a representation in which their interior geometry is part of a Euclidean AdS domain wall with complex matter fields. We compute the wave functions of scalar and tensor perturbations around homogeneous isotropic complex saddle points, turning on single scalar field matter only. We compare their predictions for the spectra of CMB perturbations with those of a different dS/CFT proposal based on the analytic continuation of inflationary universes to real asymptotically AdS domain walls. We find the predictions of both bulk calculations agree to first order in the slow roll parameters, but there is a difference at higher order which, we argue, is a signature of the HH state of the fluctuations.
Combining Cognitive Screening Tests for the Evaluation of Mild Cognitive Impairment in the Elderly
Ladeira, Rodolfo B.; Diniz, Breno S.; Nunes, Paula V.; Forlenza, Orestes V.
2009-01-01
OBJECTIVE To determine the accuracy of the Mini-Mental State Examination combined with the Verbal Fluency Test and Clock Drawing Test for the identification of patients with mild cognitive impairment and Alzheimer’s disease (AD). METHOD These tests were used to evaluate cognitive function in 247 older adults. Subjects were divided into three groups according to their cognitive state: mild cognitive impairment (n=83), AD (n=81), cognitively unimpaired controls (n=83), based on clinical and neuropsychological data. The diagnostic accuracy of each test for discriminating between these diagnostic groups (mild cognitive impairment or AD vs. controls) was examined with the aid of Receiver Operating Characteristic (ROC) curves. Additionally, we evaluated the benefit of the combination of tests on diagnostic accuracy. RESULTS Although they were accurate enough for the identification of Alzheimer’s disease, neither test alone proved adequate for the correct separation of patients with mild cognitive impairment from healthy subjects. Combining these tests did not improve diagnostic accuracy, as compared to the Mini-Mental State Examination alone, in the identification of patients with mild cognitive impairment or Alzheimer’s disease. CONCLUSIONS The present data do not warrant the combined use of the Mini-Mental State Examination, the Verbal Fluency Test and the Clock Drawing Test as a sufficient diagnostic schedule in screening for mild cognitive impairment. The present data do not support the notion that the combination of test scores is better that the use of Mini-Mental State Examination scores alone in the screening for Alzheimer’s disease. PMID:19841703
Aspects of warped AdS3/CFT2 correspondence
NASA Astrophysics Data System (ADS)
Chen, Bin; Zhang, Jia-Ju; Zhang, Jian-Dong; Zhong, De-Liang
2013-04-01
In this paper we apply the thermodynamics method to investigate the holographic pictures for the BTZ black hole, the spacelike and the null warped black holes in three-dimensional topologically massive gravity (TMG) and new massive gravity (NMG). Even though there are higher derivative terms in these theories, the thermodynamics method is still effective. It gives consistent results with the ones obtained by using asymptotical symmetry group (ASG) analysis. In doing the ASG analysis we develop a brute-force realization of the Barnich-Brandt-Compere formalism with Mathematica code, which also allows us to calculate the masses and the angular momenta of the black holes. In particular, we propose the warped AdS3/CFT2 correspondence in the new massive gravity, which states that quantum gravity in the warped spacetime could holographically dual to a two-dimensional CFT with {c_R}={c_L}=24 /{Gm{β^2√{{2( {21-4{β^2}} )}}}}.
Quantum corrections to supergravity on AdS2×S2
NASA Astrophysics Data System (ADS)
Larsen, Finn; Lisbão, Pedro
2015-04-01
We compute the off-shell spectrum of supergravity on AdS2×S2 by explicit diagonalization of the equations of motion for an effective AdS2 theory where all fields are dualized to scalars and spin-1/2 fermions. We classify all bulk modes as physical, gauge violating, and pure gauge then compute the physical spectrum by explicit cancellation of unphysical modes. We identify boundary modes as physical fields on S2 that are formally pure gauge but with gauge function that is non-normalizable on AdS2. As an application we compute the leading quantum correction to AdS2×S2 as a sum over physical fields including boundary states. The result agrees with a previous computation by Sen [1] where unphysical modes were canceled by ghosts.
Harrison, Christopher; Charles, Janice; Britt, Helena
2008-06-01
The BEACH program (Bettering the Evaluation and Care of Health) shows that management of attention deficit (hyperactivity) disorder (AD(H)D) was rare in general practice, occurring only six times per 1,000 encounters with children aged 5-17 years, between April 2000 and December 2007. This suggests that general practitioners manage AD(H)D about 46,000 times for this age group nationally each year.
NASA Technical Reports Server (NTRS)
Clauson, J.; Heuser, J.
1981-01-01
The Applications Data Service (ADS) is a system based on an electronic data communications network which will permit scientists to share the data stored in data bases at universities and at government and private installations. It is designed to allow users to readily locate and access high quality, timely data from multiple sources. The ADS Pilot program objectives and the current plans for accomplishing those objectives are described.
Images are added via the Drupal WebCMS Editor. Once an image is uploaded onto a page, it is available via the Library and your files. You can edit the metadata, delete the image permanently, and/or replace images on the Files tab.
ERIC Educational Resources Information Center
Richards, Andrew
2015-01-01
Two quantitative measures of school performance are currently used, the average points score (APS) at Key Stage 2 and value-added (VA), which measures the rate of academic improvement between Key Stage 1 and 2. These figures are used by parents and the Office for Standards in Education to make judgements and comparisons. However, simple…
NASA Astrophysics Data System (ADS)
Demleitner, M.; Eichhorn, G.; Grant, C. S.; Accomazzi, A.; Murray, S. S.; Kurtz, M. J.
1999-05-01
The bibliographic databases maintained by the NASA Astrophysics Data System are updated approximately biweekly with records gathered from over 125 sources all over the world. Data are either sent to us electronically, retrieved by our staff via semi-automated procedures, or entered in our databases through supervised OCR procedures. PERL scripts are run on the data to convert them from their incoming format to our standard format so that they can be added to the master database at SAO. Once new data has been added, separate index files are created for authors, objects, title words, and text word, allowing these fields to be searched for individually or in combination with each other. During the indexing procedure, discipline-specific knowledge is taken into account through the use of rule-based procedures performing string normalization, context-sensitive word translation, and synonym and stop word replacement. Once the master text and index files have been updated at SAO, an automated procedure mirrors the changes in the database to the ADS mirror site via a secure network connection. The use of a public domain software tool called rsync allows incremental updating of the database files, with significant savings in the amount of data being transferred. In the past year, the ADS Abstract Service databases have grown by approximately 30%, including 50% growth in Physics, 25% growth in Astronomy and 10% growth in the Instrumentation datasets. The ADS Abstract Service now contains over 1.4 million abstracts (475K in Astronomy, 430K in Physics, 510K in Instrumentation, and 3K in Preprints), 175,000 journal abstracts, and 115,000 full text articles. In addition, we provide links to over 40,000 electronic HTML articles at other sites, 20,000 PDF articles, and 10,000 postscript articles, as well as many links to other external data sources.
Not Available
1989-01-01
This bill pertains to both the assessed value of natural gas transmission property and the tax rate applied to this property. Relief would be granted if the ratio of assessed value to true market value of natural gas transmission property exceeds, by at least 5 percent, the ratio of assessed value to true market value of other commercial and industrial property in the assessment jurisdiction. No state may collect an ad valorem property tax on natural gas transmission property at a tax rate that exceeds the rate applicable to commercial and industrial property in the same assessment jurisdiction or collect any new tax, increase the rate, or remove exemptions from any tax that discriminates against a natural gas company.
Realizing "value-added" metrology
NASA Astrophysics Data System (ADS)
Bunday, Benjamin; Lipscomb, Pete; Allgair, John; Patel, Dilip; Caldwell, Mark; Solecky, Eric; Archie, Chas; Morningstar, Jennifer; Rice, Bryan J.; Singh, Bhanwar; Cain, Jason; Emami, Iraj; Banke, Bill, Jr.; Herrera, Alfredo; Ukraintsev, Vladamir; Schlessinger, Jerry; Ritchison, Jeff
2007-03-01
The conventional premise that metrology is a "non-value-added necessary evil" is a misleading and dangerous assertion, which must be viewed as obsolete thinking. Many metrology applications are key enablers to traditionally labeled "value-added" processing steps in lithography and etch, such that they can be considered integral parts of the processes. Various key trends in modern, state-of-the-art processing such as optical proximity correction (OPC), design for manufacturability (DFM), and advanced process control (APC) are based, at their hearts, on the assumption of fine-tuned metrology, in terms of uncertainty and accuracy. These trends are vehicles where metrology thus has large opportunities to create value through the engineering of tight and targetable process distributions. Such distributions make possible predictability in speed-sorts and in other parameters, which results in high-end product. Additionally, significant reliance has also been placed on defect metrology to predict, improve, and reduce yield variability. The necessary quality metrology is strongly influenced by not only the choice of equipment, but also the quality application of these tools in a production environment. The ultimate value added by metrology is a result of quality tools run by a quality metrology team using quality practices. This paper will explore the relationships among present and future trends and challenges in metrology, including equipment, key applications, and metrology deployment in the manufacturing flow. Of key importance are metrology personnel, with their expertise, practices, and metrics in achieving and maintaining the required level of metrology performance, including where precision, matching, and accuracy fit into these considerations. The value of metrology will be demonstrated to have shifted to "key enabler of large revenues," debunking the out-of-date premise that metrology is "non-value-added." Examples used will be from critical dimension (CD
Metastability in bubbling AdS space
NASA Astrophysics Data System (ADS)
Massai, Stefano; Pasini, Giulio; Puhm, Andrea
2015-02-01
We study the dynamics of probe M5 branes with dissolved M2 charge in bubbling geometries with SO(4) × SO(4) symmetry. These solutions were constructed by Bena-Warner and Lin-Lunin-Maldacena and correspond to the vacua of the maximally supersymmetric mass-deformed M2 brane theory. We find that supersymmetric probe M2 branes polarize into M5 brane shells whose backreaction creates an additional bubble in the geometry. We explicitly check that the supersymmetric polarization potential agrees with the one found within the Polchinski-Strassler approximation. The main result of this paper is that probe M2 branes whose orientation is opposite to the background flux can polarize into metastable M5 brane shells. These decay to a supersymmetric configuration via brane-flux annihilation. Our findings suggest the existence of metastable states in the mass-deformed M2 brane theory.
The inside outs of AdS3/CFT2: exact AdS wormholes with entangled CFT duals
NASA Astrophysics Data System (ADS)
Mandal, Gautam; Sinha, Ritam; Sorokhaibam, Nilakash
2015-01-01
We present the complete family of solutions of 3D gravity (Λ < 0) with two asymptotically AdS exterior regions. The solutions are constructed from data at the two boundaries, which correspond to two independent and arbitrary stress tensors T R , , and T L , . The two exteriors are smoothly joined on to an interior region through a regular horizon. We find CFT duals of these geometries which are entangled states of two CFT's. We compute correlators between general operators at the two boundaries and find perfect agreement between CFT and bulk calculations. We calculate and match the CFT entanglement entropy (EE) with the holographic EE which involves geodesics passing through the wormhole. We also compute a holographic, non-equilibrium entropy for the CFT using properties of the regular horizon. The construction of the bulk solutions here uses an exact version of Brown-Henneaux type diffeomorphisms which are asymptotically nontrivial and transform the CFT states by two independent unitary operators on the two sides. Our solutions provide an infinite family of explicit examples of the ER=EPR relation of Maldacena and Susskind [1].
AdS and Lifshitz scalar hairy black holes in Gauss-Bonnet gravity
NASA Astrophysics Data System (ADS)
Chen, Bin; Fan, Zhong-Ying; Zhu, Lu-Yao
2016-09-01
We consider Gauss-Bonnet (GB) gravity in general dimensions, which is nonminimally coupled to a scalar field. By choosing a scalar potential of the type V (ϕ )=2 Λ0+1/2 m2ϕ2+γ4ϕ4 , we first obtain large classes of scalar hairy black holes with spherical/hyperbolic/planar topologies that are asymptotic to locally anti- de Sitter (AdS) space-times. We derive the first law of black hole thermodynamics using Wald formalism. In particular, for one class of the solutions, the scalar hair forms a thermodynamic conjugate with the graviton and nontrivially contributes to the thermodynamical first law. We observe that except for one class of the planar black holes, all these solutions are constructed at the critical point of GB gravity where there exist unique AdS vacua. In fact, a Lifshitz vacuum is also allowed at the critical point. We then construct many new classes of neutral and charged Lifshitz black hole solutions for an either minimally or nonminimally coupled scalar and derive the thermodynamical first laws. We also obtain new classes of exact dynamical AdS and Lifshitz solutions which describe radiating white holes. The solutions eventually become AdS or Lifshitz vacua at late retarded times. However, for one class of the solutions, the final state is an AdS space-time with a globally naked singularity.
2 CFR 200.470 - Taxes (including Value Added Tax).
Code of Federal Regulations, 2014 CFR
2014-01-01
... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Taxes (including Value Added Tax). 200.470... Cost § 200.470 Taxes (including Value Added Tax). (a) For states, local governments and Indian tribes... Federal government for the taxes, interest, and penalties. (c) Value Added Tax (VAT) Foreign taxes...
2013-10-01
The German Ad-hoc Working Group on Indoor Guidelines of the Indoor Air Hygiene Committee and the States' Supreme Health Authorities is issuing indoor air guide values to protect public health. No suitable human studies are available for health evaluation of acetaldehyde in indoor air. In a well-documented subchronic inhalation animal study with rats assessed as reliable, local irritation effects were observed in nasal epithelia, most prominently in the olfactory epithelium with loss of olfactory neuronal cells. This study leads to a LOAEC of 48 mg acetaldehyde/m3 for continuous exposure for the endpoint nasal epithelium degeneration. By applying an interspecies factor of 1, a factor of 10 for interindividual variability, and a factor of 2 to account for the higher respiratory rate of children compared to adults, a health hazard guide value (RW II) of 1 mg acetaldehyde/m3 is obtained. A health precaution guide value (RW I) of 0.1 mg acetaldehyde/m3 is recommended.
Mysterious zero in AdS5×S5 supergravity
NASA Astrophysics Data System (ADS)
Bars, Itzhak
2002-11-01
It is shown that all the states in AdS5×S5 supergravity have zero eigenvalue for all Casimir eigenvalues of its symmetry group SU(2,2|4). To compute this zero in supergravity we refine the oscillator methods for studying the lowest weight unitary representations of SU(N,M|R+S). We solve the reduction problem when one multiplies an arbitrary number of super-doubletons. This enters in the computation of the Casimir eigenvalues of the lowest weight representations. We apply the results to SU(2,2|4) that classifies the Kaluza-Klein towers of ten-dimensional type IIB supergravity compactified on AdS5×S5. We show that the vanishing of the SU(2,2|4) Casimir eigenvalues for all the states is indeed a group-theoretical fact in AdS5×S5 supergravity. By the AdS-CFT correspondence, it is also a fact for gauge invariant states of super-Yang-Mills theory with four supersymmetries in four dimensions. This nontrivial and mysterious zero is very interesting because it is predicted as a straightforward consequence of the fundamental local Sp(2) symmetry in 2T-physics. Via the 2T-physics explanation of this zero we find a global indication that these special supergravity and super-Yang-Mills theories hide a twelve-dimensional structure with (10,2) signature.
Supersymmetry of AdS and flat IIB backgrounds
NASA Astrophysics Data System (ADS)
Beck, S.; Gutowski, J.; Papadopoulos, G.
2015-02-01
We present a systematic description of all warped AdS n × w M 10- n and IIB backgrounds and identify the a priori number of supersymmetries N preserved by these solutions. In particular, we find that the AdS n backgrounds preserve for n ≤ 4 and for 4 < n ≤ 6 supersymmetries and for suitably restricted. In addition under some assumptions required for the applicability of the maximum principle, we demonstrate that the Killing spinors of AdS n backgrounds can be identified with the zero modes of Dirac-like operators on M 10- n establishing a new class of Lichnerowicz type theorems. Furthermore, we adapt some of these results to backgrounds with fluxes by taking the AdS radius to infinity. We find that these backgrounds preserve for 2 < n ≤ 4 and for 4 < n ≤ 7 supersymmetries. We also demonstrate that the Killing spinors of AdS n × w M 10- n do not factorize into Killing spinors on AdS n and Killing spinors on M 10- n .
[Value-Added--Adding Economic Value in the Food Industry].
ERIC Educational Resources Information Center
Welch, Mary A., Ed.
1989-01-01
This booklet focuses on the economic concept of "value added" to goods and services. A student activity worksheet illustrates how the steps involved in processing food are examples of the concept of value added. The booklet further links food processing to the idea of value added to the Gross National Product (GNP). Discussion questions,…
``Short'' spinning strings and structure of quantum AdS5×S5 spectrum
NASA Astrophysics Data System (ADS)
Beccaria, M.; Giombi, S.; Macorini, G.; Roiban, R.; Tseytlin, A. A.
2012-09-01
Using information from the marginality conditions of vertex operators for the AdS5×S5 superstring, we determine the structure of the dependence of the energy of quantum string states on their conserved charges and the string tension ˜λ. We consider states on the leading Regge trajectory in the flat space limit which carry one or two (equal) spins in AdS5 or S5 and an orbital momentum in S5, with Konishi multiplet states being particular cases. We argue that the coefficients in the energy may be found by using a semiclassical expansion. By analyzing the examples of folded spinning strings in AdS5 and S5, as well as three cases of circular two-spin strings, we demonstrate the universality of transcendental (zeta-function) parts of few leading coefficients. We also show the consistency with target space supersymmetry with different states belonging to the same multiplet having the same nontrivial part of the energy. We suggest, in particular, that a rational coefficient (found by Basso for the folded string using Bethe Ansatz considerations and which, in general, is yet to be determined by a direct two-loop string calculation) should, in fact, be universal.
"Value Added" Proves Beneficial to Teacher Prep
ERIC Educational Resources Information Center
Sawchuk, Stephen
2012-01-01
The use of "value added" information appears poised to expand into the nation's teacher colleges, with more than a dozen states planning to use the technique to analyze how graduates of training programs fare in classrooms. Supporters say the data could help determine which teacher education pathways produce teachers who are at least as…
2014-06-01
The German Ad Hoc Working Group on Indoor Guidelines of the Indoor Air Hygiene Committee and the States' Supreme Health Authorities is issuing indoor air guide values to protect public health. No human studies of sufficient quality are available for the evaluation of 1-butanol in indoor air. In a well-documented oral study on reproduction toxicity in rats, assessed as reliable, impairment of embryo development was observed. Benchmark modeling of the study data by US-EPA revealed a BMDL10 of 26.1 mg/kg b.w. per day. The working group used this BMDL10 as the point of departure for the derivation of the guide value II. Considering a human respiration rate of 20 m(3) per day and a human body weight of 70 kg, this dose was converted into an inhalative concentration. Applying a factor of 0.6 to account for the inhalative absorption rate, an allometric extrapolation factor from rat to human (factor 4), an interspecies factor of 2.5 for toxicodynamics, and a factor of 10 to account for individual differences (intraspecies factor), results in a health hazard guide value (RW II) of 2 mg 1-butanol/m(3). The benchmark dose calculation of the same study generated a BMDL05 of 12.4 mg/kg b.w. per day. Applying the same assessment factors as for RW II, a precautionary guide value (RW I) of 0.7 mg 1-butanol/m(3) indoor air is calculated.
AdS3 Solutions of IIB Supergravity
Kim, Nakwoo
2005-12-02
We consider pure D3-brane configurations of IIB string theory which lead to supergravity solutions containing an AdS3 factor. They can provide new examples of AdS3/CFT2 examples on D3-branes whose worldvolume is partially compactified. When the internal 7 dimensional space is non-compact, they are related to fluctuations of higher dimensional AdS/CFT duality examples, thus dual to the BPS operators of D = 4 superconformal field theories. We find that supersymmetry requires the 7 dimensional space is warped Hopf-fibration of (real) 6 dimensional Kahler manifolds.
Matrix model maps in AdS/CFT correspondence
Donos, Aristomenis; Jevicki, Antal; Rodrigues, Joao P.
2005-12-15
We discuss an extension of a map between BPS states and free fermions. The extension involves states associated with a full two matrix problem which are constructed using a sequence of integral equations. A two parameter set of matrix model eigenstates is then related to states in SUGRA. Their wave functions are characterized by nontrivial dependence on the radial coordinate of AdS and of the Sphere, respectively. A kernel defining a one to one map between these states is then constructed.
ERIC Educational Resources Information Center
Hamin, Elisabeth M.; Marcucci, Daniel J.
2008-01-01
A new regionalism has been much documented and researched for metropolitan areas; this article documents that there is a new rural regionalism as well. In the United States, these groups appear most likely to emerge in areas that are challenged by outcomes characterizing globalization's effects on the rural condition: namely, exurban or…
Value Added in English Schools
ERIC Educational Resources Information Center
Ray, Andrew; McCormack, Tanya; Evans, Helen
2009-01-01
Value-added indicators are now a central part of school accountability in England, and value-added information is routinely used in school improvement at both the national and the local levels. This article describes the value-added models that are being used in the academic year 2007-8 by schools, parents, school inspectors, and other…
NASA Astrophysics Data System (ADS)
Clark, T. E.; ter Veldhuis, T.
2016-11-01
Coset methods are used to determine the action of a co-dimension one brane (domain wall) embedded in (d + 1)-dimensional AdS space in the Carroll limit in which the speed of light goes to zero. The action is invariant under the non-linearly realized symmetries of the AdS-Carroll spacetime. The Nambu-Goldstone field exhibits a static spatial distribution for the brane with a time varying momentum density related to the brane's spatial shape as well as the AdS-C geometry. The AdS-C vector field dual theory is obtained.
ADS Based on Linear Accelerators
NASA Astrophysics Data System (ADS)
Pan, Weimin; Dai, Jianping
An accelerator-driven system (ADS), which combines a particle accelerator with a subcritical core, is commonly regarded as a promising device for the transmutation of nuclear waste, as well as a potential scheme for thorium-based energy production. So far the predominant choice of the accelerator for ADS is a superconducting linear accelerator (linac). This article gives a brief overview of ADS based on linacs, including the motivation, principle, challenges and research activities around the world. The status and future plan of the Chinease ADS (C-ADS) project will be highlighted and discussed in depth as an example.
AdS spacetimes from wrapped D3-branes
NASA Astrophysics Data System (ADS)
Gauntlett, Jerome P.; MacConamhna, Oisín A. P.
2007-12-01
We derive a geometrical characterization of a large class of AdS3 and AdS2 supersymmetric spacetimes in type IIB supergravity with non-vanishing five-form flux using G-structures. These are obtained as special cases of a class of supersymmetric spacetimes with an {{\\bb R}}^{1,1} or {{\\bb R}} (time) factor that are associated with D3 branes wrapping calibrated two or three cycles, respectively, in manifolds with SU(2), SU(3), SU(4) and G2 holonomy. We show how two explicit AdS solutions, previously constructed in gauged supergravity, satisfy our more general G-structure conditions. For each explicit solution, we also derive a special holonomy metric which, although singular, has an appropriate calibrated cycle. After analytic continuation, some of the classes of AdS spacetimes give rise to known classes of BPS bubble solutions with {{\\bb R}}\\times {\\it SO}(4)\\times {\\it SO}(4), {{\\bb R}}\\times {\\it SO}(4)\\times U(1) and {{\\bb R}}\\times {\\it SO}(4) symmetry. These have 1/2, 1/4 and 1/8 supersymmetry, respectively. We present a new class of 1/8 BPS geometries with {{\\bb R}}\\times {\\it SU}(2) symmetry, obtained by analytic continuation of the class of AdS spacetimes associated with D3-brane wrapped on associative three cycles.
NASA Astrophysics Data System (ADS)
Kay, Bernard S.; Ortíz, L.
2014-05-01
We discuss the relationship between the bulk-boundary correspondence in Rehren's algebraic holography (and in other `fixed-background', QFT-based, approaches to holography) and in mainstream string-theoretic `Maldacena AdS/CFT'. Especially, we contrast the understanding of black-hole entropy from the point of view of QFT in curved spacetime—in the framework of 't Hooft's `brick wall' model—with the understanding based on Maldacena AdS/CFT. We show that the brick-wall modification of a Klein-Gordon field in the Hartle-Hawking-Israel state on dimensional Schwarzschild AdS has a well-defined boundary limit with the same temperature and entropy as the brick-wall-modified bulk theory. One of our main purposes is to point out a close connection, for general AdS/CFT situations, between the puzzle raised by Arnsdorf and Smolin regarding the relationship between Rehren's algebraic holography and mainstream AdS/CFT and the puzzle embodied in the `complementarity principle' proposed by Mukohyama and Israel in their work on the brick-wall approach to black hole entropy. Working on the assumption that similar results will hold for bulk QFT other than the Klein-Gordon field and for Schwarzschild AdS in other dimensions, and recalling the first author's proposed resolution to the Mukohyama-Israel puzzle based on his `matter-gravity entanglement hypothesis', we argue that, in Maldacena AdS/CFT, the algebra of the boundary CFT is isomorphic only to a proper subalgebra of the bulk algebra, albeit (at non-zero temperature) the (GNS) Hilbert spaces of bulk and boundary theories are still the `same'—the total bulk state being pure, while the boundary state is mixed (thermal). We also argue from the finiteness of its boundary (and hence, on our assumptions, also bulk) entropy at finite temperature, that the Rehren dual of the Maldacena boundary CFT cannot itself be a QFT and must, instead, presumably be something like a string theory.
Revisiting the thermodynamic relations in AdS /CMT models
NASA Astrophysics Data System (ADS)
Hyun, Seungjoon; Park, Sang-A.; Yi, Sang-Heon
2017-03-01
Motivated by the recent unified approach to the Smarr-like relation of anti-de Sitter (AdS) planar black holes in conjunction with the quasilocal formalism on conserved charges, we revisit the quantum statistical and thermodynamic relations of hairy AdS planar black holes. By extending the previous results, we identify the hairy contribution in the bulk and show that the holographic computation can be improved so that it is consistent with the bulk computation. We argue that the first law can be retained in its universal form and that the relation between the on-shell renormalized Euclidean action and its free energy interpretation in gravity may also be undeformed even with the hairy contribution in hairy AdS black holes.
Entanglement entropy for free scalar fields in AdS
NASA Astrophysics Data System (ADS)
Sugishita, Sotaro
2016-09-01
We compute entanglement entropy for free massive scalar fields in anti-de Sitter (AdS) space. The entangling surface is a minimal surface whose boundary is a sphere at the boundary of AdS. The entropy can be evaluated from the thermal free energy of the fields on a topological black hole by using the replica method. In odd-dimensional AdS, exact expressions of the Rényi entropy S n are obtained for arbitrary n. We also evaluate 1-loop corrections coming from the scalar fields to holographic entanglement entropy. Applying the results, we compute the leading difference of entanglement entropy between two holographic CFTs related by a renormalization group flow triggered by a double trace deformation. The difference is proportional to the shift of a central charge under the flow.
Diffusion and chaos from near AdS2 horizons
NASA Astrophysics Data System (ADS)
Blake, Mike; Donos, Aristomenis
2017-02-01
We calculate the thermal diffusivity D = κ/c ρ and butterfly velocity v B in holographic models that flow to AdS2 × R d fixed points in the infra-red. We show that both these quantities are governed by the same irrelevant deformation of AdS2 and hence establish a simple relationship between them. When this deformation corresponds to a universal dilaton mode of dimension Δ = 2 then this relationship is always given by D = v B 2 /(2 πT).
NASA Technical Reports Server (NTRS)
Stothers, R. B.
1984-01-01
The possible cause of the densest and most persistent dry fog on record, which was observed in Europe and the Middle East during AD 536 and 537, is discussed. The fog's long duration toward the south and the high sulfuric acid signal detected in Greenland in ice cores dated around AD 540 support the theory that the fog was due to the explosion of the Rabaul volcano, the occurrence of which has been dated at about AD 540 by the radiocarbon method.
Predictors of progression to severe Alzheimer’s disease in an incidence sample
Rabins, Peter V.; Schwartz, Sarah; Black, Betty S.; Corcoran, Christopher; Fauth, Elizabeth; Mielke, Michele; Christensen, Jessica; Lyketsos, Constantine; Tschanz, JoAnn
2013-01-01
Background Little is known about factors influencing time to severe Alzheimer’s disease (AD). Methods Incident cases of AD in the Cache County Memory Study were identified. Severe AD was defined as Mini-Mental State Examination score of ≤10 or Clinical Dementia Rating Scale score of 3; cases with either Mini-Mental State Examination score of ≥16 or Clinical Dementia Rating <2 were not categorized as severe AD. Kaplan–Meier, log-rank tests, and Cox analyses were used to identify demographic, clinical, and genetic correlates of time to progression to severe AD. Results Sixty-eight of 335 cases of incident AD developed severe dementia. In bivariate analyses, female gender, less than high school education, at least one clinically significant Neuropsychiatric Inventory domain at baseline, and the youngest and oldest ages exhibited shorter time to severe AD. In competing risk analysis, subjects with mild or at least one clinically significant Neuropsychiatric Inventory domain score, and subjects with worse health were more likely to progress to severe dementia or death. Conclusions Demographic and clinical variables predict progression to severe AD. Further study should examine whether these relationships are causal or correlational. PMID:23123228
Applicability of the abbreviated neuropsychologic battery (NEUROPSI) in Alzheimer disease patients.
Abrisqueta-Gomez, Jacqueline; Ostrosky-Solis, Feggy; Bertolucci, Paulo H F; Bueno, Orlando F A
2008-01-01
NEUROPSI is a brief neuropsychologic battery developed to briefly assess a wide spectrum of cognitive functions. The aim of this study was to examine the applicability of a Portuguese version of this battery and verify the efficacy in detecting cognitive impairment in Alzheimer disease (AD) patients. NEUROPSI was applied to 75 elderly people, 25 patients with probable AD in mild stage (AD1), 25 patients in moderate stage (AD2), and 25 healthy elderly persons (control group), matched with the AD patients for age and schooling. Before testing all participants were applied the Mini-Mental State Examination. Results showed significant differences in total scores of the tests; NEUROPSI (P<0.001) and Mini-Mental State Examination (P<0.001), and the control group scored highest in both of the tests followed by groups AD1 and AD2. Differences were also found between the initial phase and the moderate phase. Results indicate that NEUROPSI is an efficient instrument for detecting AD patients in the initial stage of the disease.
Michalski, Bernadeta; Corrada, Maria M; Kawas, Claudia H; Fahnestock, Margaret
2015-12-01
Factors associated with maintaining good cognition into old age are unclear. Decreased brain-derived neurotrophic factor (BDNF) contributes to memory loss in Alzheimer's disease (AD), and soluble assemblies of amyloid-beta (Aβ) and tau contribute to neurodegeneration. However, it is unknown whether AD-type neuropathology, soluble Aβ and tau, or levels of BDNF and its receptor tropomyosin-related kinase B (TrkB) correlate with dementia in the oldest-old. We examined these targets in postmortem Brodmann's areas 7 and 9 (BA7 and BA9) in 4 groups of subjects >90 years old: (1) no dementia/no AD pathology, (2) no dementia/AD pathology, (3) dementia/no AD pathology, (4) dementia/AD pathology. In BA7, BDNF messenger RNA correlated with Mini-Mental State Examination scores and was decreased in demented versus nondemented subjects, regardless of pathology. Soluble Aβ42 was increased in both groups with AD pathology, demented or not, compared to no dementia/no AD pathology subjects. Groups did not differ in TrkB isoform levels or in levels of total soluble tau, individual tau isoforms, threonine-181 tau phosphorylation, or ratio of phosphorylated 3R-4R isoforms. In BA9, soluble Aβ42 correlated with Mini-Mental State Examination scores and with BDNF messenger RNA expression. Thus, soluble Aβ42 and BDNF, but not TrkB or soluble tau, correlate with dementia in the oldest-old.
Coset construction of AdS particle dynamics
NASA Astrophysics Data System (ADS)
Heinze, Martin; Jorjadze, George; Megrelidze, Luka
2017-01-01
We analyze the dynamics of the AdSN+1 particle realized on the coset SO(2, N)/SO (1,N). Hamiltonian reduction provides the physical phase space in terms of the coadjoint orbit obtained by boosting a timelike element of 𝔰𝔬(2, N). We show equivalence of this approach to geometric quantization and to the SO(N) covariant oscillator description, for which the boost generators entail a complicated operator ordering. As an alternative scheme, we introduce dual oscillator variables and derive their algebra at the classical and the quantum levels. This simplifies the calculations of the commutators for the boost generators and leads to unitary irreducible representations of 𝔰𝔬(2, N) for all admissible values of the mass parameter. We furthermore discuss an SO(N) covariant supersymmetric extension of the oscillator quantization, with its realization for superparticles in AdS2 and AdS3 given by recent works.
Entanglement temperature and perturbed AdS3 geometry
NASA Astrophysics Data System (ADS)
Levine, G. C.; Caravan, B.
2016-06-01
Generalizing the first law of thermodynamics, the increase in entropy density δ S (x ) of a conformal field theory (CFT) is proportional to the increase in energy density, δ E (x ) , of a subsystem divided by a spatially dependent entanglement temperature, TE(x ) , a fixed parameter determined by the geometry of the subsystem, crossing over to thermodynamic temperature at high temperatures. In this paper we derive a generalization of the thermodynamic Clausius relation, showing that deformations of the CFT by marginal operators are associated with spatial temperature variations, δ TE(x ) , and spatial energy correlations play the role of specific heat. Using AdS/CFT duality we develop a relationship between a perturbation in the local entanglement temperature of the CFT and the perturbation of the bulk AdS metric. In two dimensions, we demonstrate a method through which direct diagonalizations of the boundary quantum theory may be used to construct geometric perturbations of AdS3 .
AdS5 backgrounds with 24 supersymmetries
NASA Astrophysics Data System (ADS)
Beck, S.; Gutowski, J.; Papadopoulos, G.
2016-06-01
We prove a non-existence theorem for smooth AdS 5 solutions with connected, compact without boundary internal space that preserve strictly 24 supersymmetries. In particular, we show that D = 11 supergravity does not admit such solutions, and that all such solutions of IIB supergravity are locally isometric to the AdS 5 × S 5 maximally supersymmetric background. Furthermore, we prove that (massive) IIA supergravity also does not admit such solutions, provided that the homogeneity conjecture for massive IIA supergravity is valid. In the context of AdS/CFT these results imply that if gravitational duals for strictly mathcal{N}=3 superconformal theories in 4-dimensions exist, they are either singular or their internal spaces are not compact.
Partition functions with spin in AdS2 via quasinormal mode methods
NASA Astrophysics Data System (ADS)
Keeler, Cynthia; Lisbão, Pedro; Ng, Gim Seng
2016-10-01
We extend the results of [1], computing one loop partition functions for massive fields with spin half in AdS2 using the quasinormal mode method proposed by Denef, Hartnoll, and Sachdev [2]. We find the finite representations of SO(2, 1) for spin zero and spin half, consisting of a highest weight state | h> and descendants with non-unitary values of h. These finite representations capture the poles and zeroes of the one loop determinants. Together with the asymptotic behavior of the partition functions (which can be easily computed using a large mass heat kernel expansion), these are sufficient to determine the full answer for the one loop determinants. We also discuss extensions to higher dimensional AdS2 n and higher spins.
Hunt, M E; Kissling, F
1993-01-01
Feminization of patriarchal institutions is necessary in order to eliminate the exclusivity and mutuality of hierarchical, gender, class, and race stratification. The aim of this paper is to explain the history and activities surrounding the New York Times ad on Sunday, October 7, 1984 (the Catholic Statement on Pluralism and Abortion signed by Barbara Ferraro and Patricia Hussey of the Sisters of Note Dame de Namur, Rose Dominic Trapasso of the Maryknoll Sisters, and 67 other signers). The significance of this ad for Roman Catholic feminists and suggestions for new models of relationships between feminists is given. The Statement was written by Daniel Maguire and Frances Kissling and reviewed by 20 Roman Catholic ethicists. A sponsoring committee of early signers sought other support. Catholics for a Free Choice sponsored the funding for circulation of the Statement among professional societies, but not necessarily canonical communities. Publication of the entire statement in the Times was at the height of the presidential campaign. Conservative Bishops Bernard Law of Boston and John O'Connor of Boston publicly denounced Ferraro's position. The first institutional church response came on November 14, 1984, and stated that the Statement was personal opinion and contradictory to clear and constant church teachings about abortion. On November 30, 1984, Cardinal Jean Jerome Hamer of the Congregation for Religious and Secular Institutes responded to most presidents of canonical communities to request a public retraction from signers under threat of dismissal. The issue was obedience to the church. Several members of the canonical community and priests published retractions; negotiations with the Vatican began. Freedom of conscience and empowerment of canonical communities, as agents of their own lives, were given as reasons for the challenge to paternalism. The response was that women were subject to obedience within their communities and had taken public vows and were
Merged Sounding Value-Added Product
Troyan, D
2010-03-03
The Merged Sounding value-added product (VAP) uses a combination of observations from radiosonde soundings, the microwave radiometer (MWR), surface meteorological instruments, and European Centre for Medium-Range Weather Forecasts (ECMWF) model output with a sophisticated scaling/interpolation/smoothing scheme in order to define profiles of the atmospheric thermodynamic state at one-minute temporal intervals and a total of 266 altitude levels.
Is School Value Added Indicative of Principal Quality?
ERIC Educational Resources Information Center
Chiang, Hanley; Lipscomb, Stephen; Gill, Brian
2016-01-01
States across the country are developing systems for evaluating school principals on the basis of student achievement growth. A common approach is to hold principals accountable for the value added of their schools--that is, schools' contributions to student achievement growth. In theory, school value added can reflect not only principals'…
Designing added functions in engineered cementitious composites
NASA Astrophysics Data System (ADS)
Yang, En-Hua
In this dissertation, a new and systematic material design approach is developed for ECC with added functions through material microstructures linkage to composite macroscopic behavior. The thesis research embodies theoretical development by building on previous ECC micromechanical models, and experimental investigations into three specific new versions of ECC with added functions aimed at addressing societal demands of our built infrastructure. Specifically, the theoretical study includes three important ECC modeling elements: Steady-state crack propagation analyses and simulation, predictive accuracy of the fiber bridging constitutive model, and development of the rate-dependent strain-hardening criteria. The first element establishes the steady-state cracking criterion as a fundamental requirement for multiple cracking behavior in brittle matrix composites. The second element improves the accuracy of crack-width prediction in ECC. The third element establishes the micromechanics basis for impact-resistant ECC design. Three new ECCs with added functions were developed and experimentally verified in this thesis research through the enhanced theoretical framework. A green ECC incorporating a large volume of industrial waste was demonstrated to possess reduced crack width and drying shrinkage. The self-healing ECC designed with tight crack width was demonstrated to recover transport and mechanical properties after microcrack damage when exposed to wet and dry cycles. The impact-resistant ECC was demonstrated to retain tensile ductility with increased strength under moderately high strain-rate loading. These new versions of ECC with added functions are expected to contribute greatly to enhancing the sustainability, durability, and safety of civil infrastructure built with ECC. This research establishes the effectiveness of micromechanics-based design and material ingredient tailoring for ECC with added new attributes but without losing its basic tensile ductile
NASA Astrophysics Data System (ADS)
Gauntlett, Jerome P.; Gutowski, Jan B.; Suryanarayana, Nemani V.
2004-11-01
We analyse a one-parameter family of supersymmetric solutions of type IIB supergravity that includes AdS5 × S5. For small values of the parameter the solutions are causally well behaved, but beyond a critical value closed timelike curves (CTCs) appear. The solutions are holographically dual to {\\cal N}=4 supersymmetric Yang Mills theory on a non-conformally flat background with non-vanishing R-currents. We compute the holographic energy momentum tensor for the spacetime and show that it remains finite even when the CTCs appear. The solutions, as well as the uplift of some recently discovered AdS5 black-hole solutions, are shown to preserve precisely two supersymmetries.
Supersymmetric AdS_6 solutions of type IIB supergravity
NASA Astrophysics Data System (ADS)
Kim, Hyojoong; Kim, Nakwoo; Suh, Minwoo
2015-10-01
We study the general requirement for supersymmetric AdS_6 solutions in type IIB supergravity. We employ the Killing spinor technique and study the differential and algebraic relations among various Killing spinor bilinears to find the canonical form of the solutions. Our result agrees precisely with the work of Apruzzi et al. (JHEP 1411:099, 2014), which used the pure spinor technique. Hoping to identify the geometry of the problem, we also computed four-dimensional theory through the dimensional reduction of type IIB supergravity on AdS_6. This effective action is essentially a non-linear sigma model with five scalar fields parametrizing {SL}(3,{R})/{SO}(2,1), modified by a scalar potential and coupled to Einstein gravity in Euclidean signature. We argue that the scalar potential can be explained by a subgroup CSO(1,1,1) subset {SL}(3,{R}) in a way analogous to gauged supergravity.
Universal isolation in the AdS landscape
NASA Astrophysics Data System (ADS)
Danielsson, U. H.; Dibitetto, G.; Vargas, S. C.
2016-12-01
We study the universal conditions for quantum nonperturbative stability against bubble nucleation for pertubatively stable AdS vacua based on positive energy theorems. We also compare our analysis with the preexisting ones in the literature carried out within the thin-wall approximation. The aforementioned criterion is then tested in two explicit examples describing massive type IIA string theory compactified on S3 and S3×S3, respectively. The AdS landscape of both classes of compactifications is known to consist of a set of isolated points. The main result is that all critical points respecting the Breitenlohner-Freedman (BF) bound also turn out be stable at a nonperturbative level. Finally, we speculate on the possible universal features that may be extracted from the above specific examples.
Tachyon inflation in an AdS braneworld with backreaction
NASA Astrophysics Data System (ADS)
Bilić, Neven; Dimitrijevic, Dragoljub D.; Djordjevic, Goran S.; Milosevic, Milan
2017-02-01
We analyze the inflationary scenario based on the tachyon field coupled with the radion of the second Randall-Sundrum model (RSII). The tachyon Lagrangian is derived from the dynamics of a 3-brane moving in the five-dimensional bulk. The AdS5 geometry of the bulk is extended to include the radion. Using the Hamiltonian formalism we find four nonlinear field equations supplemented by the modified Friedmann equations of the RSII braneworld cosmology. After a suitable rescaling we reduce the parameters of our model to only one free parameter related to the brane tension and the AdS5 curvature. We solve the equations numerically assuming a reasonably wide range of initial conditions determined by physical considerations. Varying the free parameter and initial conditions we confront our results with the Planck 2015 data.
Ambitwistors, oscillators and massless fields on AdS5
NASA Astrophysics Data System (ADS)
Uvarov, D. V.
2016-11-01
Positive energy unitary irreducible representations of SU (2 , 2) can be constructed with the aid of bosonic oscillators in (anti)fundamental representation of SU(2)L × SU(2)R that are closely related to Penrose twistors. Starting with the correspondence between the doubleton representations, homogeneous functions on projective twistor space and on-shell generalized Weyl curvature SL (2 , C) spinors and their low-spin counterparts, we study in the similar way the correspondence between the massless representations, homogeneous functions on ambitwistor space and, via the Penrose transform, with the gauge fields on Minkowski boundary of AdS5. The possibilities of reconstructing massless fields on AdS5 and some applications are also discussed.
Interpolated Sounding Value-Added Product
Troyan, D
2013-04-01
The Interpolated Sounding (INTERPSONDE) value-added product (VAP) uses a combination of observations from radiosonde soundings, the microwave radiometer (MWR), and surface meteorological instruments in order to define profiles of the atmospheric thermodynamic state at one-minute temporal intervals and a total of at least 266 altitude levels. This VAP is part of the Merged Sounding (MERGESONDE) suite of VAPs. INTERPSONDE is the profile of the atmospheric thermodynamic state created using the algorithms of MERGESONDE without including the model data from the European Centre for Medium-range Weather Forecasting (ECMWF). More specifically, INTERPSONDE VAP represents an intermediate step within the larger MERGESONDE process.
NASA Astrophysics Data System (ADS)
Avery, Steven G.; Chowdhury, Borun D.
2014-10-01
Several recent papers argue against firewalls by relaxing the requirement for locality outside the stretched horizon. In the firewall argument, locality essentially serves the purpose of ensuring that the degrees of freedom required for infall are those in the proximity of the black hole and not the ones in the early radiation. We make the firewall argument sharper by utilizing the AdS/CFT framework and claim that the firewall argument essentially states that the dual to a thermal state in the CFT is a firewall.
Generalised structures for N=1 AdS backgrounds
NASA Astrophysics Data System (ADS)
Coimbra, André; Strickland-Constable, Charles
2016-11-01
We expand upon a claim made in a recent paper [arXiv:1411.5721] that generic minimally supersymmetric AdS backgrounds of warped flux compactifications of Type II and M theory can be understood as satisfying a straightforward weak integrability condition in the language of {E}_{d(d)}× {R}+ generalised geometry. Namely, they are spaces admitting a generalised G-structure set by the Killing spinor and with constant singlet generalised intrinsic torsion.
Shock Wave Collisions and Thermalization in AdS_5
NASA Astrophysics Data System (ADS)
Kovchegov, Y. V.
We study heavy ion collisions at strong 't Hooft coupling usingAdS/CFT correspondence. According to the AdS/CFT dictionary heavy ion collisions correspond to gravitational shock wave collisions in AdS_5. We construct the metric in the forward light cone after the collision perturbatively through expansion of Einstein equations in graviton exchanges. We obtain an analytic expression for the metric including all-order graviton exchanges with one shock wave, while keeping the exchanges with another shock wave at the lowest order. We read off the corresponding energy-momentum tensor of the produced medium. Unfortunately this energy-momentum tensor does not correspond to ideal hydrodynamics, indicating that higher order graviton exchanges are needed to construct the full solution of the problem. We also show that shock waves must completely stop almost immediately after the collision in AdS_5, which, on the field theory side, corresponds to complete nuclear stopping due to strong coupling effects, likely leading to Landau hydrodynamics. Finally, we perform trapped surface analysis of the shock wave collisions demonstrating that a bulk black hole, corresponding to ideal hydrodynamics on the boundary, has to be created in such collisions, thus constructing a proof of thermalization in heavy ion collisions at strong coupling.
Near horizon soft hairs as microstates of generic AdS3 black holes
NASA Astrophysics Data System (ADS)
Sheikh-Jabbari, M. M.; Yavartanoo, H.
2017-02-01
In [1] the horizon fluffs proposal is put forward to identify microstates of generic nonextremal three-dimensional Bañados-Teitelboim-Zanelli (BTZ) black holes. The proposal is that black hole microstates, the horizon fluffs, are certain near horizon soft hairs which are not in the coadjoint orbits of the asymptotic Virasoro algebra associated with the BTZ black holes. It is also known that AdS3 Einstein gravity has more general black hole solutions than the BTZ family which are generically described by two periodic, but otherwise arbitrary, holomorphic and antiholomorphic functions. We show that these general AdS3 black holes which are typically conformal descendants of the BTZ black holes and are characterized by the associated Virasoro coadjoint orbits, appear as coherent states in the asymptotic symmetry algebra corresponding to the black hole family. We apply the horizon fluffs proposal to these generic AdS3 black holes and identify the corresponding microstates. We then perform microstate counting and compute the entropy. The entropy appears to be an orbit invariant quantity, providing an important check for the horizon fluffs proposal.
Stringy correlations on deformed AdS3 × S 3
NASA Astrophysics Data System (ADS)
Roychowdhury, Dibakar
2017-03-01
In this paper, following the basic prescriptions of Gauge/String duality, we perform a strong coupling computation on classical two point correlation between local (single trace) operators in a gauge theory dual to κ-deformed AdS3 × S 3 background. Our construction is based on the prescription that relates every local operator in a gauge theory to that with the (semi)classical string states propagating within the physical region surrounded by the holographic screen in deformed AdS3. In our analysis, we treat strings as being that of a point like object located near the physical boundary of the κ-deformed Euclidean Poincare AdS3 and as an extended object with non trivial dynamics associated to S 3. It turns out that in the presence of small background deformations, the usual power law behavior associated with two point functions is suppressed exponentially by a non trivial factor which indicates a faster decay of two point correlations with larger separations. On the other hand, in the limit of large background deformations ( κ ≫ 1), the corresponding two point function reaches a point of saturation. In our analysis, we also compute finite size corrections associated with these two point functions at strong coupling. As a consistency check of our analysis, we find perfect agreement between our results to that with the earlier observations made in the context of vanishing deformation.
The generalized added mass revised
NASA Astrophysics Data System (ADS)
De Wilde, Juray
2007-05-01
The reformulation of the generalized or apparent added mass presented by De Wilde [Phys. Fluids 17, 113304 (2005)] neglects the presence of a drag-type force in the gas and solid phase momentum equations. Reformulating the generalized added mass accounting for the presence of a drag-type force, an apparent drag force appears next to the apparent distribution of the filtered gas phase pressure gradient over the phases already found by De Wilde in the above-cited reference. The reformulation of the generalized added mass and the evaluation of a linear wave propagation speed test then suggest a generalized added mass type closure approach to completely describe filtered gas-solid momentum transfer, that is, including both the filtered drag force and the correlation between the solid volume fraction and the gas phase pressure gradient.
NASA Technical Reports Server (NTRS)
1980-01-01
The Ames-Dryden (AD)-1 was a research aircraft designed to investigate the concept of an oblique (or pivoting) wing. The movie clip runs about 17 seconds and has two air-to-air views of the AD-1. The first shot is from slightly above as the wing pivots to 60 degrees. The other angle is almost directly below the aircraft when the wing is fully pivoted.
Holographic p-Wave Superconductors in Quintessence AdS Black Hole Spacetime
NASA Astrophysics Data System (ADS)
Chen, Song-Bai; Pan, Qi-Yuan
2013-10-01
We construct a holographic p-wave superconductor model in the background of quintessence AdS black hole with an SU(2) Yang—Mills gauge field and then probe the effects of quintessence on the holographic p-wave superconductor. We investigate the relation between the critical temperature and the state parameter of quintessence, and present the numerical results for electric conductivity. It is shown that the condensation of the vector field becomes harder as the absolute value of the state parameter increases. Unlike the scalar condensate in the s-wave model, the condensation of the vector field in p-wave model can occur in the total value range of the state parameter wq of quintessence. These results could help us know more about holographic superconductor and dark energy.
Ding, Xin; Ding, Jurong; Hua, Bo; Xiong, Xingzhong; Xiao, Li; Peng, Fang; Chen, Lin; Pan, Xianfang; Wang, Qingsong
2017-02-09
There is increasing evidence that white matter lesions (WMLs) are associated with cognitive impairments. The purpose of this study was to explore the relationship of WMLs with cognitive impairments from the aspect of cortical functional activity. Briefly, Sixteen patients with ischemic WMLs and 13 controls participated in this study. A regional homogeneity (ReHo) approach was used to investigate altered neural coherence in patients with ischemic WMLs during the resting state. A correlation analysis was further performed between regions with altered ReHo and cognitive test scores, including Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA), in the patient group. Finally, we found regions with altered ReHo values in patients with ischemic WMLs to be involved in default mode network (DMN), frontal-parietal control network (FPCN), dorsal attention network (DAN), motor network and right temporal cortex. Moreover, some altered regions belonging to DMN, FPCN and motor network were significantly correlated with cognitive test scores. Our results provide neuroimaging evidence for the impairments of memory, attention, executive and motor function in patients with ischemic WMLs. It is interesting to note that the decreased ReHo was mainly in the anterior brain regions, while increased ReHo in the posterior brain regions, which may indicate a failure down regulation of spontaneous activity in posterior regions. In summary, this study indicates an important role of specific cortical dysfunction in cognitive associated with WMLs.
Cheng, Huaidong; Li, Wen; Gong, Liang; Xuan, Han; Huang, Zhonglian; Zhao, Hong; Wang, Long Sheng; Wang, Kai
2017-01-01
In this study, we aimed to investigate the intrinsic hippocampal functional connectivity (FC) network and its relationship with prospective memory in patients with breast cancer suffering from chemotherapy-induced cognitive impairment (CICI). Thirty-four breast cancer patients before and after adjuvant chemotherapy (CB and CC, respectively) and 31 age- and education-matched cognitively normal (CN) women were recruited and subjected to a prospective memory task and a resting-state functional magnetic resonance imaging scan. Seed-based functional connectivity analysis was used to compare the hippocampal FC networks between CC and CN groups. Partial correction analysis was used to examine the association between the hippocampal FC network and prospective memory in the CC group. The cancer group that underwent chemotherapy obtained significantly poorer scores than the CN group on mini-mental state examination, verbal fluency test, digit span, and prospective memory examination. Compared to the CN group, CC group showed increased hippocampal connectivity in the frontal and parietal cortex, precuneus, posterior cingulate cortex, and the cerebellum. In addition, the increasing hippocampal FC networks were negatively correlated with prospective memory performance in the CC group. These findings suggest maladaptive hippocampal functioning as a mechanism underlying the impairment of prospective memory in patients experiencing CICI. PMID:28327626
Cheng, Huaidong; Li, Wen; Gong, Liang; Xuan, Han; Huang, Zhonglian; Zhao, Hong; Wang, Long Sheng; Wang, Kai
2017-03-22
In this study, we aimed to investigate the intrinsic hippocampal functional connectivity (FC) network and its relationship with prospective memory in patients with breast cancer suffering from chemotherapy-induced cognitive impairment (CICI). Thirty-four breast cancer patients before and after adjuvant chemotherapy (CB and CC, respectively) and 31 age- and education-matched cognitively normal (CN) women were recruited and subjected to a prospective memory task and a resting-state functional magnetic resonance imaging scan. Seed-based functional connectivity analysis was used to compare the hippocampal FC networks between CC and CN groups. Partial correction analysis was used to examine the association between the hippocampal FC network and prospective memory in the CC group. The cancer group that underwent chemotherapy obtained significantly poorer scores than the CN group on mini-mental state examination, verbal fluency test, digit span, and prospective memory examination. Compared to the CN group, CC group showed increased hippocampal connectivity in the frontal and parietal cortex, precuneus, posterior cingulate cortex, and the cerebellum. In addition, the increasing hippocampal FC networks were negatively correlated with prospective memory performance in the CC group. These findings suggest maladaptive hippocampal functioning as a mechanism underlying the impairment of prospective memory in patients experiencing CICI.
ERIC Educational Resources Information Center
Congress of the U.S., Washington, DC. Senate Committee on the Judiciary.
A hearing was held on the role of prevention in the comprehensive drug control policy of the United States. The hearing demonstrated a strengthening of the commitment to reduce the demand for drugs. It also showed bi-partisan support to remain vigilant in defense of the borders and in punishing those who sell or manufacture drugs. It states that…
Euclidean and Noetherian entropies in AdS space
Dutta, Suvankar; Gopakumar, Rajesh
2006-08-15
We examine the Euclidean action approach, as well as that of Wald, to the entropy of black holes in asymptotically AdS spaces. From the point of view of holography these two approaches are somewhat complementary in spirit and it is not obvious why they should give the same answer in the presence of arbitrary higher derivative gravity corrections. For the case of the AdS{sub 5} Schwarzschild black hole, we explicitly study the leading correction to the Bekenstein-Hawking entropy in the presence of a variety of higher derivative corrections studied in the literature, including the Type IIB R{sup 4} term. We find a nontrivial agreement between the two approaches in every case. Finally, we give a general way of understanding the equivalence of these two approaches.
NASA Astrophysics Data System (ADS)
Accomazzi, Alberto; Kurtz, M. J.; Henneken, E. A.; Grant, C. S.; Thompson, D.; Di Milia, G.; Luker, J.; Murray, S. S.
2013-01-01
The NASA Astrophysics Data System (ADS) has been working hard on updating its services and interfaces to better support our community's research needs. ADS Labs is a new interface built on the old tried-and-true ADS Abstract Databases, so all of ADS's content is available through it. In this presentation we highlight the new features that have been developed in ADS Labs over the last year: new recommendations, metrics, a citation tool and enhanced fulltext search. ADS Labs has long been providing article-level recommendations based on keyword similarity, co-readership and co-citation analysis of its corpus. We have now introduced personal recommendations, which provide a list of articles to be considered based on a individual user's readership history. A new metrics interface provides a summary of the basic impact indicators for a list of records. These include the total and normalized number of papers, citations, reads, and downloads. Also included are some of the popular indices such as the h, g and i10 index. The citation helper tool allows one to submit a set of records and obtain a list of top 10 papers which cite and/or are cited by papers in the original list (but which are not in it). The process closely resembles the network approach of establishing "friends of friends" via an analysis of the citation network. The full-text search service now covers more than 2.5 million documents, including all the major astronomy journals, as well as physics journals published by Springer, Elsevier, the American Physical Society, the American Geophysical Union, and all of the arXiv eprints. The full-text search interface interface allows users and librarians to dig deep and find words or phrases in the body of the indexed articles. ADS Labs is available at http://adslabs.org
Heavy quark potential from deformed AdS5 models
NASA Astrophysics Data System (ADS)
Zhang, Zi-qiang; Hou, De-fu; Chen, Gang
2017-04-01
In this paper, we investigate the heavy quark potential in some holographic QCD models. The calculation relies on a modified renormalization scheme mentioned in a previous work of Albacete et al. After studying the heavy quark potential in Pirner-Galow model and Andreev-Zakharov model, we extend the discussion to a general deformed AdS5 case. It is shown that the obtained potential is negative definite for all quark-antiquark separations, differs from that using the usual renormalization scheme.
The AdS central charge in string theory
NASA Astrophysics Data System (ADS)
Troost, Jan
2011-11-01
We evaluate the vacuum expectation value of the central charge operator in string theory in an AdS3 vacuum. Our calculation provides a rare non-zero one-point function on a spherical worldsheet. The evaluation involves the regularization both of a worldsheet ultraviolet divergence (associated to the infinite volume of the conformal Killing group), and a space-time infrared divergence (corresponding to the infinite volume of space-time). The two divergences conspire to give a finite result, which is the classical general relativity value for the central charge, corrected in bosonic string theory by an infinite series of tree level higher derivative terms.
Internal structure of charged AdS black holes
NASA Astrophysics Data System (ADS)
Bhattacharjee, Srijit; Sarkar, Sudipta; Virmani, Amitabh
2016-06-01
When an electrically charged black hole is perturbed, its inner horizon becomes a singularity, often referred to as the Poisson-Israel mass inflation singularity. Ori constructed a model of this phenomenon for asymptotically flat black holes, in which the metric can be determined explicitly in the mass inflation region. In this paper we implement the Ori model for charged AdS black holes. We find that the mass function inflates faster than the flat space case as the inner horizon is approached. Nevertheless, the mass inflation singularity is still a weak singularity: Although spacetime curvature becomes infinite, tidal distortions remain finite on physical objects attempting to cross it.
NASA Astrophysics Data System (ADS)
Accomazzi, Alberto; Kurtz, M. J.; Henneken, E. A.; Grant, C. S.; Thompson, D.; Luker, J.; Chyla, R.; Murray, S. S.
2014-01-01
In the spring of 1993, the Smithsonian/NASA Astrophysics Data System (ADS) first launched its bibliographic search system. It was known then as the ADS Abstract Service, a component of the larger Astrophysics Data System effort which had developed an interoperable data system now seen as a precursor of the Virtual Observatory. As a result of the massive technological and sociological changes in the field of scholarly communication, the ADS is now completing the most ambitious technological upgrade in its twenty-year history. Code-named ADS 2.0, the new system features: an IT platform built on web and digital library standards; a new, extensible, industrial strength search engine; a public API with various access control capabilities; a set of applications supporting search, export, visualization, analysis; a collaborative, open source development model; and enhanced indexing of content which includes the full-text of astronomy and physics publications. The changes in the ADS platform affect all aspects of the system and its operations, including: the process through which data and metadata are harvested, curated and indexed; the interface and paradigm used for searching the database; and the follow-up analysis capabilities available to the users. This poster describes the choices behind the technical overhaul of the system, the technology stack used, and the opportunities which the upgrade is providing us with, namely gains in productivity and enhancements in our system capabilities.
Lodged in the throat: internal infinities and AdS/CFT
NASA Astrophysics Data System (ADS)
Marolf, Don; Yarom, Amos
2006-01-01
In the context of AdS3/CFT2, we address spacetimes with a certain sort of internal infinity as typified by the extreme BTZ black hole. The internal infinity is a null circle lying at the end of the black hole's infinite throat. We argue that such spacetimes may be described by a product CFT of the form CFTLotimesCFTR, where CFTR is associated with the asymptotically AdS boundary while CFTL is associated with the null circle. Our particular calculations analyze the CFT dual of the extreme BTZ black hole in a linear toy model of AdS3/CFT2. Since the BTZ black hole is a quotient of AdS3, the dual CFT state is a corresponding quotient of the CFT vacuum state. This state turns out to live in the aforementioned product CFT. We discuss this result in the context of general issues of AdS/CFT duality and entanglement entropy.
Conserved charges in timelike warped AdS3 spaces
NASA Astrophysics Data System (ADS)
Donnay, L.; Fernández-Melgarejo, J. J.; Giribet, G.; Goya, A.; Lavia, E.
2015-06-01
We consider the timelike version of warped anti-de Sitter space (WAdS), which corresponds to the three-dimensional section of the Gödel solution of four-dimensional cosmological Einstein equations. This geometry presents closed timelike curves (CTCs), which are inherited from its four-dimensional embedding. In three dimensions, this type of solution can be supported without matter provided the graviton acquires mass. Here, among the different ways to consistently give mass to the graviton in three dimensions, we consider the parity-even model known as new massive gravity (NMG). In the bulk of timelike WAdS3 space, we introduce defects that, from the three-dimensional point of view, represent spinning massive particlelike objects. For this type of source, we investigate the definition of quasilocal gravitational energy as seen from infinity, far beyond the region where the CTCs appear. We also consider the covariant formalism applied to NMG to compute the mass and the angular momentum of spinning particlelike defects and compare the result with the one obtained by means of the quasilocal stress tensor. We apply these methods to special limits in which the WAdS3 solutions coincide with locally AdS3 and locally AdS2×R spaces. Finally, we make some comments about the asymptotic symmetry algebra of asymptotically WAdS3 spaces in NMG.
AdS nonlinear instability: moving beyond spherical symmetry
NASA Astrophysics Data System (ADS)
Dias, Óscar J. C.; Santos, Jorge E.
2016-12-01
Anti-de Sitter (AdS) is conjectured to be nonlinear unstable to a weakly turbulent mechanism that develops a cascade towards high frequencies, leading to black hole formation (Dafermos and Holzegel 2006 Seminar at DAMTP (University of Cambridge) available at https://dpmms.cam.ac.uk/~md384/ADSinstability.pdf, Bizon and Rostworowski 2011 Phys. Rev. Lett. 107 031102). We give evidence that the gravitational sector of perturbations behaves differently from the scalar one studied by Bizon and Rostworowski. In contrast with Bizon and Rostworowski, we find that not all gravitational normal modes of AdS can be nonlinearly extended into periodic horizonless smooth solutions of the Einstein equation. In particular, we show that even seeds with a single normal mode can develop secular resonances, unlike the spherically symmetric scalar field collapse studied by Bizon and Rostworowski. Moreover, if the seed has two normal modes, more than one resonance can be generated at third order, unlike the spherical collapse of Bizon and Rostworowski. We also show that weak turbulent perturbative theory predicts the existence of direct and inverse cascades, with the former dominating the latter for equal energy two-mode seeds.
Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD
Colton, Carol A; Mott, Ryan T; Sharpe, Hayley; Xu, Qing; Van Nostrand, William E; Vitek, Michael P
2006-01-01
Background Microglia are associated with neuritic plaques in Alzheimer disease (AD) and serve as a primary component of the innate immune response in the brain. Neuritic plaques are fibrous deposits composed of the amyloid beta-peptide fragments (Abeta) of the amyloid precursor protein (APP). Numerous studies have shown that the immune cells in the vicinity of amyloid deposits in AD express mRNA and proteins for pro-inflammatory cytokines, leading to the hypothesis that microglia demonstrate classical (Th-1) immune activation in AD. Nonetheless, the complex role of microglial activation has yet to be fully explored since recent studies show that peripheral macrophages enter an "alternative" activation state. Methods To study alternative activation of microglia, we used quantitative RT-PCR to identify genes associated with alternative activation in microglia, including arginase I (AGI), mannose receptor (MRC1), found in inflammatory zone 1 (FIZZ1), and chitinase 3-like 3 (YM1). Results Our findings confirmed that treatment of microglia with anti-inflammatory cytokines such as IL-4 and IL-13 induces a gene profile typical of alternative activation similar to that previously observed in peripheral macrophages. We then used this gene expression profile to examine two mouse models of AD, the APPsw (Tg-2576) and Tg-SwDI, models for amyloid deposition and for cerebral amyloid angiopathy (CAA) respectively. AGI, MRC1 and YM1 mRNA levels were significantly increased in the Tg-2576 mouse brains compared to age-matched controls while TNFα and NOS2 mRNA levels, genes commonly associated with classical activation, increased or did not change, respectively. Only TNFα mRNA increased in the Tg-SwDI mouse brain. Alternative activation genes were also identified in brain samples from individuals with AD and were compared to age-matched control individuals. In AD brain, mRNAs for TNFα, AGI, MRC1 and the chitinase-3 like 1 and 2 genes (CHI3L1; CHI3L2) were significantly increased
32 CFR 2800.7 - Designation of chairperson for Ad Hoc Committees.
Code of Federal Regulations, 2013 CFR
2013-07-01
... VICE PRESIDENT OF THE UNITED STATES SECURITY PROCEDURES § 2800.7 Designation of chairperson for Ad Hoc Committees. The Counsel to the Vice President is designated as the responsible official to chair Ad...
32 CFR 2800.7 - Designation of chairperson for Ad Hoc Committees.
Code of Federal Regulations, 2014 CFR
2014-07-01
... VICE PRESIDENT OF THE UNITED STATES SECURITY PROCEDURES § 2800.7 Designation of chairperson for Ad Hoc Committees. The Counsel to the Vice President is designated as the responsible official to chair Ad...
32 CFR 2800.7 - Designation of chairperson for Ad Hoc Committees.
Code of Federal Regulations, 2012 CFR
2012-07-01
... VICE PRESIDENT OF THE UNITED STATES SECURITY PROCEDURES § 2800.7 Designation of chairperson for Ad Hoc Committees. The Counsel to the Vice President is designated as the responsible official to chair Ad...
Separating Growth from Value Added
ERIC Educational Resources Information Center
Yeagley, Raymond
2007-01-01
This article discusses Rochester's two academic models that offer different tools for different purposes--measuring individual learning and measuring what affects learning. The main focus of currently available growth measures is formative assessment--providing data to inform instructional planning. Value-added assessment is not a student…
Adding Value to Indiana's Commodities.
ERIC Educational Resources Information Center
Welch, Mary A., Ed.
1995-01-01
Food processing plants are adding value to bulk and intermediate products to sell overseas. The Asian Pacific Rim economies constituted the largest market for consumer food products in 1993. This shift toward consumer food imports in this area is due to more women working outside the home, the internationalization of populations, and dramatic…
Courtship American Style: Newspaper Ads
ERIC Educational Resources Information Center
Cameron, Catherine; And Others
1977-01-01
This study investigated an increasing social phenomenon--newspaper advertising for dating or marital partners--in terms of the bargaining process involved. Content analysis of personal ads in a popular "respectable" singles newspaper revealed a pattern of offers and requests reminiscent of a heterosexual stock market. (Author)
An investigation of AdS2 backreaction and holography
NASA Astrophysics Data System (ADS)
Engelsöy, Julius; Mertens, Thomas G.; Verlinde, Herman
2016-07-01
We investigate a dilaton gravity model in AdS2 proposed by Almheiri and Polchinski [1] and develop a 1d effective description in terms of a dynamical boundary time with a Schwarzian derivative action. We show that the effective model is equivalent to a 1d version of Liouville theory, and investigate its dynamics and symmetries via a standard canonical framework. We include the coupling to arbitrary conformal matter and analyze the effective action in the presence of possible sources. We compute commutators of local operators at large time separation, and match the result with the time shift due to a gravitational shockwave interaction. We study a black hole evaporation process and comment on the role of entropy in this model.
Supersymmetry Properties of AdS Supergravity Backgrounds
NASA Astrophysics Data System (ADS)
Beck, Samuel; Gutowski, Jan; Papadopoulos, George
2017-01-01
Anti-de Sitter supergravity backgrounds are of particular interest in light of the AdS/CFT correspondence, which relates them to dual conformal field theories on the boundary of the anti-de Sitter space. We have investigated the forms of the supersymmetries these backgrounds preserve by solving the Killing spinor equations on the anti-de Sitter components of these spaces. We have found that a supersymmetric AdSn background necessarily preserves 2⌊n/2⌋ k supersymmetries for n <= 4 and 2 ⌊n/2 ⌋ + 1 k supersymmetries for 4 < n <= 7 , k ∈N> 0 . Additionally, we have found that the Killing spinors of each background are exactly the zeroes of a Dirac-like operator constructed from the Killing spinor equations.
The Massive Wave Equation in Asymptotically AdS Spacetimes
NASA Astrophysics Data System (ADS)
Warnick, C. M.
2013-07-01
We consider the massive wave equation on asymptotically AdS spaces. We show that the timelike F behaves like a finite timelike boundary, on which one may impose the equivalent of Dirichlet, Neumann or Robin conditions for a range of (negative) mass parameter which includes the conformally coupled case. We demonstrate well posedness for the associated initial-boundary value problems at the H 1 level of regularity. We also prove that higher regularity may be obtained, together with an asymptotic expansion for the field near F. The proofs rely on energy methods, tailored to the modified energy introduced by Breitenlohner and Freedman. We do not assume the spacetime is stationary, nor that the wave equation separates.
On jordanian deformations of AdS5 and supergravity
NASA Astrophysics Data System (ADS)
Hoare, Ben; van Tongeren, Stijn J.
2016-10-01
We consider various homogeneous Yang-Baxter deformations of the {{AdS}}5× {{{S}}}5 superstring that can be obtained from the η-deformed superstring and related models by singular boosts. The jordanian deformations we obtain in this way behave similarly to the η-deformed model with regard to supergravity: T dualizing the classical sigma model it is possible to find corresponding solutions of supergravity, which, however, have dilatons that prevent T dualizing back. Hence the backgrounds of these jordanian deformations are not solutions of supergravity. Still, they do satisfy a set of recently found modified supergravity equations which implies that the corresponding sigma models are scale invariant. The abelian models that we obtain by singular boosts do directly correspond to solutions of supergravity. In addition to our main results we consider contraction limits of our main example, which do correspond to supergravity solutions.
Systematics of Coupling Flows in AdS Backgrounds
Goldberger, Walter D.; Rothstein, Ira Z.
2003-03-18
We give an effective field theory derivation, based on the running of Planck brane gauge correlators, of the large logarithms that arise in the predictions for low energy gauge couplings in compactified AdS}_5 backgrounds, including the one-loop effects of bulk scalars, fermions, and gauge bosons. In contrast to the case of charged scalars coupled to Abelian gauge fields that has been considered previously in the literature, the one-loop corrections are not dominated by a single 4D Kaluza-Klein mode. Nevertheless, in the case of gauge field loops, the amplitudes can be reorganized into a leading logarithmic contribution that is identical to the running in 4D non-Abelian gauge theory, and a term which is not logarithmically enhanced and is analogous to a two-loop effect in 4D. In a warped GUT model broken by the Higgs mechanism in the bulk,we show that the matching scale that appears in the large logarithms induced by the non-Abelian gauge fields is m_{XY}^2/k where m_{XY} is the bulk mass of the XY bosons and k is the AdS curvature. This is in contrast to the UV scale in the logarithmic contributions of scalars, which is simply the bulk mass m. Our results are summarized in a set of simple rules that can be applied to compute the leading logarithmic predictions for coupling constant relations within a given warped GUT model. We present results for both bulk Higgs and boundary breaking of the GUT gauge
ERIC Educational Resources Information Center
Frazier, Andrea P.
2012-01-01
This research study employed a mixed method sequential approach and investigated the number of Schools of Medicine within the United States that offer health literacy as a component of their curriculum and a course of study within the academic setting. Data were gathered from medical school surveys and personal interviews. Curriculum content,…
Holography beyond conformal invariance and AdS isometry?
Barvinsky, A. O.
2015-03-15
We suggest that the principle of holographic duality be extended beyond conformal invariance and AdS isometry. Such an extension is based on a special relation between functional determinants of the operators acting in the bulk and on its boundary, provided that the boundary operator represents the inverse propagators of the theory induced on the boundary by the Dirichlet boundary value problem in the bulk spacetime. This relation holds for operators of a general spin-tensor structure on generic manifolds with boundaries irrespective of their background geometry and conformal invariance, and it apparently underlies numerous O(N{sup 0}) tests of the AdS/CFT correspondence, based on direct calculation of the bulk and boundary partition functions, Casimir energies, and conformal anomalies. The generalized holographic duality is discussed within the concept of the “double-trace” deformation of the boundary theory, which is responsible in the case of large-N CFT coupled to the tower of higher-spin gauge fields for the renormalization group flow between infrared and ultraviolet fixed points. Potential extension of this method beyond the one-loop order is also briefly discussed.
2015-07-01
In the European Hazardous Substances Regulation No 1272/2008 trichloroethylene has been classified as a probable human carcinogen and a suspected mutagen. According to several Committees (German Committee on Hazardous Substances, European Scientific Committee on Occupational Exposure Limits, European Chemicals Agency´s Committee for Risk Assessment (ECHA-RAC)) concentrations of trichloroethylene cytotoxic to renal tubuli may increase the risk to develop renal cancer. At non-cytotoxic concentrations of trichloroethylene a much lower cancer risk may be assumed. Therefore, evaluating the cancer risk to the public following inhalation of trichloroethylene ECHA-RAC has assumed a sublinear exposure-response relationship for carcinogenicity of trichloroethylene. Specifically, ECHA-RAC assessed a cancer risk of 6.4 × 10(- 5) (mg/m(3))(- 1) following life time exposure to trichloroethylene below a NOAEC for renal cytotoxicity of 6 mg trichloroethylene/m(3). Further evaluation yields a life-time risk of 10(- 6) corresponding to 0.02 mg trichloroethylene/m(3). This concentration is well above the reference (e.g. background) concentration of trichloroethylene in indoor air. Consequently the Ad-hoc Working Group on Indoor Guidelines recommends 0.02 mg trichloroethylene/m(3) as a risk-related guideline for indoor air. Measures to reduce exposure are considered inappropriate at concentrations below this guideline.
8. View of gabeon west wall added downstream from the ...
8. View of gabeon west wall added downstream from the lower dam. Photograph taken from east side of Millstone Creek. VIEW SOUTH - Loleta Recreation Area, Lower Dam, 6 miles Southeast of interesection of State Route 24041 & State Route 66, Loleta, Elk County, PA
Caregiver burden and coping in early-stage Alzheimer disease.
Zucchella, Chiara; Bartolo, Michelangelo; Pasotti, Chiara; Chiapella, Laura; Sinforiani, Elena
2012-01-01
This study was set out to describe caregiver-perceived burden and coping in early-stage Alzheimer disease (AD). A total of 163 consecutive pairs of patients with AD and their principal caregivers were initially recruited. The caregivers completed the Caregiver Burden Inventory (CBI) and the Coping Orientations to Problems Experienced scale, and also provided sociodemographic information; the patients with AD were assessed by means of the Mini Mental State Examination and the Neuropsychiatric Inventory. Data from 126 patient-caregiver pairs were analyzed. The caregivers (mean age 56.11±12.37 y) were mainly women (76%); 64% were the patient's offspring; 39% lived with the patient. From the CBI data, it emerged that caregivers perceived loss of personal time (objective burden, 33%) and the feeling of missing out on opportunities (developmental burden, 25%) as their main stressors. Total CBI score was negatively correlated with Mini Mental State Examination (P=0.005). As regards coping strategies, the caregivers predominantly used problem-oriented strategies associated with a positive attitude. The use of dysfunctional strategies was predictive of caregiver burden. It is important to be aware that avoidance and dysfunctional coping strategies predispose caregivers of patients with AD to higher level of distress, whereas successful caregiving seems to be based on the use of problem-oriented strategies early in the disease when solutions are still available.
Quantum compositeness of gravity: black holes, AdS and inflation
Dvali, Gia; Gomez, Cesar E-mail: cesar.gomez@uam.es
2014-01-01
Gravitational backgrounds, such as black holes, AdS, de Sitter and inflationary universes, should be viewed as composite of N soft constituent gravitons. It then follows that such systems are close to quantum criticality of graviton Bose-gas to Bose-liquid transition. Generic properties of the ordinary metric description, including geodesic motion or particle-creation in the background metric, emerge as the large-N limit of quantum scattering of constituent longitudinal gravitons. We show that this picture correctly accounts for physics of large and small black holes in AdS, as well as reproduces well-known inflationary predictions for cosmological parameters. However, it anticipates new effects not captured by the standard semi-classical treatment. In particular, we predict observable corrections that are sensitive to the inflationary history way beyond last 60 e-foldings. We derive an absolute upper bound on the number of e-foldings, beyond which neither de Sitter nor inflationary Universe can be approximated by a semi-classical metric. However, they could in principle persist in a new type of quantum eternity state. We discuss implications of this phenomenon for the cosmological constant problem.
Quantum compositeness of gravity: black holes, AdS and inflation
Dvali, Gia; Gomez, Cesar
2014-01-14
Gravitational backgrounds, such as black holes, AdS, de Sitter and inflationary universes, should be viewed as composite of N soft constituent gravitons. It then follows that such systems are close to quantum criticality of graviton Bose-gas to Bose-liquid transition. Generic properties of the ordinary metric description, including geodesic motion or particle-creation in the background metric, emerge as the large-N limit of quantum scattering of constituent longitudinal gravitons. We show that this picture correctly accounts for physics of large and small black holes in AdS, as well as reproduces well-known inflationary predictions for cosmological parameters. However, it anticipates new effects not captured by the standard semi-classical treatment. In particular, we predict observable corrections that are sensitive to the inflationary history way beyond last 60 e-foldings. We derive an absolute upper bound on the number of e-foldings, beyond which neither de Sitter nor inflationary Universe can be approximated by a semi-classical metric. However, they could in principle persist in a new type of quantum eternity state. We discuss implications of this phenomenon for the cosmological constant problem.
Soft walls in dynamic AdS /QCD and the technidilaton
NASA Astrophysics Data System (ADS)
Evans, Nick; Jones, Peter; Scott, Marc
2015-11-01
Dynamic AdS /QCD is a modification of AdS /QCD that includes the running of the anomalous dimension of the q ¯q quark bilinear and in which the generation of the constituent quark mass plays the role of an IR wall. The model allows one to move away smoothly from the controlled spectrum of the N =2 super Yang-Mills theory of the D3/probe-D7 system to more QCD-like theories with chiral symmetry breaking. We investigate soft wall behavior in the model that gives Regge trajectories with Mn,s 2˜n ,s . To achieve these behaviors requires the quark's constituent mass to fall peculiarly sharply in the IR so that meson physics is sensitive to renormalization group (RG) scales well below the quark's on-shell mass. Including soft wall behavior in models of walking gauge dynamics breaks the near conformal symmetry which is present above the quark on-shell mass which can generate a large mass for the technidilaton like state. We conclude that the meson spectrum is rather sensitive to the IR decoupling.
The exceptional generalised geometry of supersymmetric AdS flux backgrounds
NASA Astrophysics Data System (ADS)
Ashmore, Anthony; Petrini, Michela; Waldram, Daniel
2016-12-01
We analyse generic AdS flux backgrounds preserving eight supercharges in D = 4 and D = 5 dimensions using exceptional generalised geometry. We show that they are described by a pair of globally defined, generalised structures, identical to those that appear for flat flux backgrounds but with different integrability conditions. We give a number of explicit examples of such "exceptional Sasaki-Einstein" backgrounds in type IIB supergravity and M-theory. In particular, we give the complete analysis of the generic AdS5 M-theory backgrounds. We also briefly discuss the structure of the moduli space of solutions. In all cases, one structure defines a "generalised Reeb vector" that generates a Killing symmetry of the background corresponding to the R-symmetry of the dual field theory, and in addition encodes the generic contact structures that appear in the D = 4 M-theory and D = 5 type IIB cases. Finally, we investigate the relation between generalised structures and quantities in the dual field theory, showing that the central charge and R-charge of BPS wrapped-brane states are both encoded by the generalised Reeb vector, as well as discussing how volume minimisation (the dual of a- and F-maximisation) is encoded.
Stability of charged global AdS4 spacetimes
NASA Astrophysics Data System (ADS)
Arias, Raúl; Mas, Javier; Serantes, Alexandre
2016-09-01
We study linear and nonlinear stability of asymptotically AdS4 solutions in Einstein-Maxwell-scalar theory. After summarizing the set of static solutions we first examine thermodynamical stability in the grand canonical ensemble and the phase transitions that occur among them. In the second part of the paper we focus on nonlinear stability in the microcanonical ensemble by evolving radial perturbations numerically. We find hints of an instability corner for vanishingly small perturbations of the same kind as the ones present in the uncharged case. Collapses are avoided, instead, if the charge and mass of the perturbations come to close the line of solitons. Finally we examine the soliton solutions. The linear spectrum of normal modes is not resonant and instability turns on at extrema of the mass curve. Linear stability extends to nonlinear stability up to some threshold for the amplitude of the perturbation. Beyond that, the soliton is destroyed and collapses to a hairy black hole. The relative width of this stability band scales down with the charge Q, and does not survive the blow up limit to a planar geometry.
AdS4/CFT3 squashed, stretched and warped
NASA Astrophysics Data System (ADS)
Klebanov, Igor R.; Klose, Thomas; Murugan, Arvind
2009-03-01
We use group theoretic methods to calculate the spectrum of short multiplets around the extremum of Script N = 8 gauged supergravity potential which possesses Script N = 2 supersymmetry and SU(3) global symmetry. Upon uplifting to M-theory, it describes a warped product of AdS4 and a certain squashed and stretched 7-sphere. We find quantum numbers in agreement with those of the gauge invariant operators in the Script N = 2 superconformal Chern-Simons theory recently proposed to be the dual of this M-theory background. This theory is obtained from the U(N) × U(N) theory through deforming the superpotential by a term quadratic in one of the superfields. To construct this model explicitly, one needs to employ monopole operators whose complete understanding is still lacking. However, for the U(2) × U(2) gauge theory we make a proposal for the form of the monopole operators which has a number of desired properties. In particular, this proposal implies enhanced symmetry of the U(2) × U(2) ABJM theory for k = 1,2; it makes its similarity to and subtle difference from the BLG theory quite explicit.
NASA Astrophysics Data System (ADS)
Goodman, Alyssa
We will create the first interactive sky map of astronomers' understanding of the Universe over time. We will accomplish this goal by turning the NASA Astrophysics Data System (ADS), widely known for its unrivaled value as a literature resource, into a data resource. GIS and GPS systems have made it commonplace to see and explore information about goings-on on Earth in the context of maps and timelines. Our proposal shows an example of a program that lets a user explore which countries have been mentioned in the New York Times, on what dates, and in what kinds of articles. By analogy, the goal of our project is to enable this kind of exploration-on the sky-for the full corpus of astrophysical literature available through ADS. Our group's expertise and collaborations uniquely position us to create this interactive sky map of the literature, which we call the "ADS All-Sky Survey." To create this survey, here are the principal steps we need to follow. First, by analogy to "geotagging," we will "astrotag," the ADS literature. Many "astrotags" effectively already exist, thanks to curation efforts at both CDS and NED. These efforts have created links to "source" positions on the sky associated with each of the millions of articles in the ADS. Our collaboration with ADS and CDS will let us automatically extract astrotags for all existing and future ADS holdings. The new ADS Labs, which our group helps to develop, includes the ability for researchers to filter article search results using a variety of "facets" (e.g. sources, keywords, authors, observatories, etc.). Using only extracted astrotags and facets, we can create functionality like what is described in the Times example above: we can offer a map of the density of positions' "mentions" on the sky, filterable by the properties of those mentions. Using this map, researchers will be able to interactively, visually, discover what regions have been studied for what reasons, at what times, and by whom. Second, where
32 CFR 2800.7 - Designation of chairperson for Ad Hoc Committees.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 6 2010-07-01 2010-07-01 false Designation of chairperson for Ad Hoc Committees... VICE PRESIDENT OF THE UNITED STATES SECURITY PROCEDURES § 2800.7 Designation of chairperson for Ad Hoc Committees. The Counsel to the Vice President is designated as the responsible official to chair Ad...
32 CFR 2800.7 - Designation of chairperson for Ad Hoc Committees.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 6 2011-07-01 2011-07-01 false Designation of chairperson for Ad Hoc Committees... VICE PRESIDENT OF THE UNITED STATES SECURITY PROCEDURES § 2800.7 Designation of chairperson for Ad Hoc Committees. The Counsel to the Vice President is designated as the responsible official to chair Ad...
Zheng, Li Juan; Yang, Gui Fen; Zhang, Xin Yuan; Wang, Yun Fei; Liu, Ya; Zheng, Gang; Lu, Guang Ming; Zhang, Long Jiang; Han, Ying
2017-02-15
Neuroimaging studies have demonstrated that the major depression disorder would increase the risk of dementia in the older with amnestic cognitive impairment. We used granger causality analysis algorithm to explore the amygdala- and hippocampus-based directional connectivity patterns in 12 patients with major depression disorder and amnestic cognitive impairment (mean age: 69.5 ± 10.3 years), 13 amnestic cognitive impairment patients (mean age: 72.7 ± 8.5 years) and 14 healthy controls (mean age: 64.7 ± 7.0 years). Compared with amnestic cognitive impairment patients and control groups respectively, the patients with both major depression disorder and amnestic cognitive impairment displayed increased effective connectivity from the right amygdala to the right lingual and calcarine gyrus, as well as to the bilateral supplementary motor areas. Meanwhile, the patients with both major depression disorder and amnestic cognitive impairment had enhanced effective connectivity from the left superior parietal gyrus, superior and middle occipital gyrus to the left hippocampus, the z values of which was also correlated with the scores of mini-mental state examination and auditory verbal learning test-immediate recall. Our findings indicated that the directional effective connectivity of right amygdala - occipital-parietal lobe - left hippocampus might be the pathway by which major depression disorder inhibited the brain activity in patients with amnestic cognitive impairment.
POSSIBLE CHROMOSPHERIC ACTIVITY CYCLES IN AD LEO
Buccino, Andrea P.; Petrucci, Romina; Mauas, Pablo J. D.; Jofré, Emiliano
2014-01-20
AD Leo (GJ 388) is an active dM3 flare star that has been extensively observed both in the quiescent and flaring states. Since this active star is near the fully convective boundary, studying its long-term chromospheric activity in detail could be an appreciable contribution to dynamo theory. Here, using the Lomb-Scargle periodogram, we analyze the Ca II K line-core fluxes derived from CASLEO spectra obtained between 2001 and 2013 and the V magnitude from the ASAS database between 2004 and 2010. From both of these totally independent time series, we obtain a possible activity cycle with a period of approximately seven years and a less significant shorter cycle of approximately two years. A tentative interpretation is that a dynamo operating near the surface could be generating the longer cycle, while a second dynamo operating in the deep convection zone could be responsible for the shorter one. Based on the long duration of our observing program at CASLEO and the fact that we observe different spectral features simultaneously, we also analyze the relation between simultaneous measurements of the Na I index (R{sub D}{sup ′}), Hα, and Ca II K fluxes at different activity levels of AD Leo, including flares.
Membranes from monopole operators in ABJM theory: Large angular momentum and M-theoretic AdS4/CFT3
NASA Astrophysics Data System (ADS)
Kovacs, Stefano; Sato, Yuki; Shimada, Hidehiko
2014-09-01
We study the duality between M-theory in AdS_4 × S^7/{Z}_k and the ABJM {N}=6 Chern-Simons-matter theory with gauge group U(N) × {U}(N) and level k, taking N large and k of order 1. In this M-theoretic regime the lack of an explicit formulation of M-theory in AdS_4 × S^7/{Z}_k makes the gravity side difficult, while the CFT is strongly coupled and the planar approximation is not applicable. We focus on states on the gravity side with large angular momentum J≫ 1 associated with a single plane of rotation in S^7 and identify their dual operators in the CFT. We show that natural approximation schemes arise on both sides thanks to the presence of the small parameter 1/J. On the AdS side, we use the matrix model of M-theory on the maximally supersymmetric pp-wave background with matrices of size J/k. A perturbative treatment of this matrix model provides a good approximation to M-theory in AdS_4 × S^7/{Z}_k when N^{1/3}≪ J≪ N^{1/2}. On the CFT side, we study the theory on S^2× {R} with magnetic flux J/k. A Born-Oppenheimer-type expansion arises naturally for large J in spite of the theory being strongly coupled. The energy spectra on the two sides agree at leading order. This provides a non-trivial test of the AdS_4/CFT_3 correspondence including near-BPS observables associated with membrane degrees of freedom, thus verifying the duality beyond the previously studied sectors corresponding to either BPS observables or the type IIA string regime.
Poorzamany Nejat Kermany, Mahtab; Dahi, Mastaneh; Yamini Sharif, Reyhaneh; Radpay, Badiozaman
2016-01-01
Background Dexmedetomidine is a potent and highly specific α2-adrenoreceptor agonist that induces sedative and analgesic effects over a short-term period. As a result of these benefits, dexmedetomidine may be a better alternative than other available drugs for keeping the patient’s cognition state in an acceptable condition after outpatient ophthalmic surgeries. Objectives This randomized study was conducted to compare the sedative effects of dexmedetomidine and remifentanil on the cognitive state of patients who have undergone cataract surgery. Patients and Methods A total of 100 patients who were candidates for cataract surgery under local anesthesia received either dexmedetomidine (50 patients; D group) or remifentanil (50 patients; R group) in a double-blind, randomized study. The baseline cardiovascular status and mini mental state examination (MMSE) score for each patient were recorded. As a loading dose, dexmedetomidine (0.5 µg/kg) and remifentanil (0.1 µg/kg) were infused at 10 minutes and 5 minutes before topical anesthesia, respectively. Subsequently, the maintenance dose was administered at 0.2 µg/kg/hour and 0.05 µg/kg/minutes in the D and R groups, respectively. The surgical procedure was begun when the bispectral index (BIS) reached 70 - 80. MMSE test was done at a postanesthetic care unit (PACU) 120 minutes after the discontinuation of the drug. Results There was no statistically significant difference between the MMSE scores of the two groups before surgery (P = 0.6), but the MMSE test conducted at the PACU revealed significantly better cognitive outcomes in the D group than in the R group in patients younger and older than 65 years (P = 0.03 and P = 0.0001, respectively). Conclusions This study revealed that dexmedetomidine may be a suitable agent for sedation in cataract surgery because it results in a more favorable postoperative cognitive status than remifentanil. Likewise, dexmedetomidine had no significant adverse effects on
AD, the ALICE diffractive detector
NASA Astrophysics Data System (ADS)
Tello, Abraham Villatoro
2017-03-01
ALICE is one of the four large experiments at the CERN Large Hadron Collider (LHC). As a complement to its Heavy-Ion physics program, ALICE started during Run 1 of LHC an extensive program dedicated to the study of proton-proton diffractive processes. In order to optimize its trigger efficiencies and purities in selecting diffractive events, the ALICE Collaboration installed a very forward AD detector during the Long Shut Down 1 of LHC. This new forward detector system consists of two stations made of two layers of scintillator pads, one station on each side of the interaction point. With this upgrade, ALICE has substantially increased its forward physics coverage, including the double rapidity gap based selection of central production, as well as the measurements of inclusive diffractive cross sections.
Competition between Two Isolates of Denitrifying Bacteria Added to Soil
Murray, Robert E.; Parsons, Laura L.; Smith, M. Scott
1992-01-01
We examined the competitive relationship between two isolates of denitrifying bacteria, both of which grow well under aerobic conditions but differ in their ability to grow under denitrifying conditions. The growth and persistence of the two isolates, added to sterile soil or added to soil previously colonized by the other isolate, were monitored under aerobic and denitrifying (anaerobic) conditions. When isolates were added together to sterile soil, the isolate added at the higher density reduced the growth of the isolate added at the lower density. The magnitude of the growth reduction varied depending on the competitive abilities of the individual isolates and the aeration state of the soil. Prior colonization of soil with one of the isolates conferred a competitive advantage on the colonized isolate but did not lead to the disappearance of the challenging isolate. Fluctuations in aeration state caused large changes in the population density of one isolate and altered the competitive relationship between the two isolates. The competitive effectiveness of each isolate varied with cell density, the degree of prior colonization of the soil by the other isolate, and the aeration state of the soil. PMID:16348820
Matrix model maps and reconstruction of AdS supergravity interactions
Cremonini, Sera; Mello Koch, Robert de; Jevicki, Antal
2008-05-15
We consider the question of reconstructing (cubic) SUGRA interactions in AdS/CFT. The method we introduce is based on the matrix model maps (MMP) which were previously successfully employed at the linearized level. The strategy is to start with the map for 1/2 BPS configurations, which is exactly known (to all orders) in the Hamiltonian framework. We then use the extension of the matrix model map with the corresponding Ward identities to completely specify the interaction. A central point in this construction is the nonvanishing of off-shell interactions (even for highest-weight states)
Receiver-Based Ad Hoc On Demand Multipath Routing Protocol for Mobile Ad Hoc Networks
Al-Nahari, Abdulaziz; Mohamad, Mohd Murtadha
2016-01-01
Decreasing the route rediscovery time process in reactive routing protocols is challenging in mobile ad hoc networks. Links between nodes are continuously established and broken because of the characteristics of the network. Finding multiple routes to increase the reliability is also important but requires a fast update, especially in high traffic load and high mobility where paths can be broken as well. The sender node keeps re-establishing path discovery to find new paths, which makes for long time delay. In this paper we propose an improved multipath routing protocol, called Receiver-based ad hoc on demand multipath routing protocol (RB-AOMDV), which takes advantage of the reliability of the state of the art ad hoc on demand multipath distance vector (AOMDV) protocol with less re-established discovery time. The receiver node assumes the role of discovering paths when finding data packets that have not been received after a period of time. Simulation results show the delay and delivery ratio performances are improved compared with AOMDV. PMID:27258013
Value-Added Assessment of Teacher Preparation: Implications for Special Education
ERIC Educational Resources Information Center
Gansle, Kristin A.; Noell, George H.; Grandstaff-Beckers, Gerlinde; Stringer, Angelle; Roberts, Nancy; Burns, Jeanne M.
2015-01-01
As states move to teacher evaluation that is intended to capture teacher contributions to students' learning outcomes, some states have adopted "value-added measures" to examine teachers' and teacher preparation programs' effectiveness. In Louisiana, the value-added assessment of teacher preparation programs includes students with…
A Quantitative Analysis of Brain Soluble Tau and the Tau Secretion Factor.
Han, Pengcheng; Serrano, Geidy; Beach, Thomas G; Caselli, Richard J; Yin, Junxiang; Zhuang, Ningning; Shi, Jiong
2017-01-09
Neurofibrillary tangles (NFTs) represent products of insoluble tau protein in the brains of patients with Alzheimer disease (AD). The cerebrospinal fluid (CSF) tau level is a biomarker in AD diagnosis. The soluble portion of tau protein in brain parenchyma is presumably the source for CSF tau but this has not previously been quantified. We measured CSF tau and soluble brain tau at autopsy in temporal and frontal brain tissue samples from 7 cognitive normal, 12 mild cognitively impaired, and 19 AD subjects. Based on the measured brain soluble tau, we calculated the whole brain tau load and estimated tau secretion factor. Our results suggest that the increase in NFT in AD is likely attributable to post-translational processes; the increase in CSF tau in AD patients is due to an accelerated carrier-based secretion. Moreover, cognitive dysfunction assessed by final Mini-Mental State Examination scores correlated with the secretion factor but not with the soluble tau.
The Persistence of School-Level Value-Added
ERIC Educational Resources Information Center
Briggs, Derek C.; Weeks, Jonathan P.
2011-01-01
Using longitudinal data for an entire state from 2004 to 2008, this article describes the results from an empirical investigation of the persistence of value-added school effects on student achievement in reading and math. It shows that when schools are the principal units of analysis rather than teachers, the persistence of estimated school…
Teacher Effects, Value-Added Models, and Accountability
ERIC Educational Resources Information Center
Konstantopoulos, Spyros
2014-01-01
Background: In the last decade, the effects of teachers on student performance (typically manifested as state-wide standardized tests) have been re-examined using statistical models that are known as value-added models. These statistical models aim to compute the unique contribution of the teachers in promoting student achievement gains from grade…
ERIC Educational Resources Information Center
Dichter, Harriet
2011-01-01
Elected state leaders often prioritize economic prosperity and competitiveness, which provides an important opportunity too rarely taken for investing in early education. In 2003, Pennsylvania recognized the connection between early education and the economy, and smartly embraced early learning as part of its economic prosperity and…
Wang, Hongjie; Ducournau, Corinne; Saydaminova, Kamola; Richter, Maximilian; Yumul, Roma; Ho, Martin; Carter, Darrick; Zubieta, Chloé
2015-01-01
ABSTRACT We recently discovered that desmoglein 2 (DSG2) is a receptor for human adenovirus species B serotypes Ad3, Ad7, Ad11, and Ad14. Ad3 is considered to be a widely distributed human pathogen. Ad3 binding to DSG2 triggers the transient opening of epithelial junctions. Here, we further delineate the mechanism that leads to DSG2-mediated epithelial junction opening in cells exposed to Ad3 and recombinant Ad3 fiber proteins. We identified an Ad3 fiber knob-dependent pathway that involves the phosphorylation of mitogen-activated protein (MAP) kinases triggering the activation of the matrix-metalloproteinase ADAM17. ADAM17, in turn, cleaves the extracellular domain of DSG2 that links epithelial cells together. The shed DSG2 domain can be detected in cell culture supernatant and also in serum of mice with established human xenograft tumors. We then extended our studies to Ad14 and Ad14P1. Ad14 is an important research and clinical object because of the recent appearance of a new, more pathogenic strain (Ad14P1). In a human epithelial cancer xenograft model, Ad14P1 showed more efficient viral spread and oncolysis than Ad14. Here, we tested the hypothesis that a mutation in the Ad14P1 fiber knob could account for the differences between the two strains. While our X-ray crystallography studies suggested an altered three-dimensional (3D) structure of the Ad14P1 fiber knob in the F-G loop region, this did not significantly change the fiber knob affinity to DSG2 or the intracellular signaling and DSG2 shedding in epithelial cancer cells. IMPORTANCE A number of widely distributed adenoviruses use the epithelial junction protein DSG2 as a receptor for infection and lateral spread. Interaction with DSG2 allows the virus not only to enter cells but also to open epithelial junctions which form a physical barrier to virus spread. Our study elucidates the mechanism beyond virus-triggered junction opening with a focus on adenovirus serotype 3. Ad3 binds to DSG2 with its fiber
Condom ads promote illicit sex.
Kippley, J F
1994-01-01
Written in 1987, this opinion was republished in the wake of US President Bill Clinton's AIDS prevention media campaign promoting condom use which began January 1994, targeted at young adults aged 18-25. The author staunchly opposes condom use even though he admits that people do not consider abstinence from sex to be a serious option for the prevention of HIV/STD infection. He believes that there is no moral use of sex with a condom and that condoms have always been a sign of immorality, be it prostitution, adultery, fornication, or marital contraception. Likewise, the author laments the success enjoyed by Planned Parenthood in achieving the social acceptance of marital contraception and sex outside of marriage. The complete social acceptance of homosexual activity, however, remains to be achieved. Magazines, newspapers, and television receive income in exchange for publishing or airing advertisements. Finding offensive advertisements which promote the use of condoms against HIV infection, the author recommends writing letters of complaint to the responsible media sources. If the television stations or publications in question continue to advertise condoms to the public, stop watching them or end one's subscriptions to the particular printed media. Such action taken collectively among many individuals will reduce product sales and income, and potentially sway corporate policy against condom ads.
16 CFR 460.18 - Insulation ads.
Code of Federal Regulations, 2011 CFR
2011-01-01
... INSULATION § 460.18 Insulation ads. (a) If your ad gives an R-value, you must give the type of insulation and... your ad gives a price, you must give the type of insulation, the R-value at a specific thickness, the... you give the price per square foot, you do not have to give the coverage area. (c) If your ad...
16 CFR 460.18 - Insulation ads.
Code of Federal Regulations, 2010 CFR
2010-01-01
... INSULATION § 460.18 Insulation ads. (a) If your ad gives an R-value, you must give the type of insulation and... your ad gives a price, you must give the type of insulation, the R-value at a specific thickness, the... you give the price per square foot, you do not have to give the coverage area. (c) If your ad...
Myths & Facts about Value-Added Analysis
ERIC Educational Resources Information Center
TNTP, 2011
2011-01-01
This paper presents myths as well as facts about value-added analysis. These myths include: (1) "Value-added isn't fair to teachers who work in high-need schools, where students tend to lag far behind academically"; (2) "Value-added scores are too volatile from year-to-year to be trusted"; (3) "There's no research behind value-added"; (4) "Using…
New Features in the ADS Abstract Service
NASA Technical Reports Server (NTRS)
Eichhorn, Guenther; Accomazzi, Alberto; Grant, Carolyn S.; Kurtz, Michael J.; Henneken, Edwin A.; Thompson, Donna M.; Murray, Stephen S.
2005-01-01
The NASA-ADS Abstract Service provides a sophisticated search capability for the literature in Astronomy, Planetary Sciences, Physics/Geophysics, and Space Instrumentation. The ADS is funded by NASA and access to the ADS services is free to anybody world-wide without restrictions. It allows the user to search the literature by author, title, and abstract text.
27 CFR 19.456 - Adding denaturants.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Adding denaturants. 19.456... Denaturation § 19.456 Adding denaturants. Denaturants and spirits shall be mixed in packages, tanks, or bulk... proprietor shall submit a flow diagram of the intended process or method of adding denaturants. (Sec....
Weighing the Claims in Diet Ads
... página en español Weighing the Claims in Diet Ads Related Items Weight Loss Challenge Diet Ads and ... control Information Network . The Truth Behind Weight Loss Ads Claims to watch out for include: Lose weight ...
Historical Literature in the ADS
NASA Astrophysics Data System (ADS)
Eichhorn, G.; Kurtz, M. J.; Accomazzi, A.; Grant, C. S.
1997-12-01
The Astrophysics Data System at http://adswww.harvard.edu is in the process of scanning the historical astronomical literature and making it available through the World Wide Web. We have scanned several volumes from the early 1800's of the "Astronomische Nachrichten", and the "Monthly Notices of the Royal Astronomical Society", the two oldest astronomical journals. We also have several of the early volumes of the "Astrophysical Journal" and the "Astronomical Journal" available. For all the journals that we cover, we have scanned volume 1. These early volumes can be accessed on a page-by-page basis. We plan to continue to scan this historical literature and complete these journals within the next year. We are also collaborating with a preservation project at Harvard University. This project will microfilm selected parts of astronomical Observatory reports. We plan to scan these microfilms to produce electronic images of these reports and put them on-line in the ADS. We hope to eventually cover most of the astronomical literature. In order to organize the scanned pages into articles, we need tables of contents (ToC). The early issues of the journals did not have printed ToC pages, so this needs to be done by hand. We do not have the financial resources to build these ToCs. We are looking for collaborators who would be willing to work with us in building these ToCs for the older journals and observatory reports. If you are interested in such a project, please contact the first author at gei@cfa.harvard.edu.
ERIC Educational Resources Information Center
Loeb, Susanna
2013-01-01
The question for this brief is whether education leaders can use value-added measures as tools for improving schooling and, if so, how to do this. Districts, states, and schools can, at least in theory, generate gains in educational outcomes for students using value-added measures in three ways: creating information on effective programs, making…
New instantons in AdS4/CFT3 from D4-branes wrapping some of CP3
NASA Astrophysics Data System (ADS)
Naghdi, M.
2013-07-01
With use of a 6-form field strength of ten-dimensional type IIA supergravity over AdS4×CP3, when S7/Zk is considered as a S1 Hopf fibration on CP3, we earn a fully localized solution in the bulk of Euclideanized AdS4. Indeed, this object appears in the external space because of wrapping a D4(M5)-brane over some parts of the respective internal spaces. Interestingly, this supersymmetry breaking SU(4)×U(1)-singlet mode exists in already known spectra when one uses the 8c gravitino representation of SO(8). To adjust the boundary theory, we should swap the original 8s and 8c representations for supercharges and fermions in the Aharony-Bergman-Jafferis-Maldacena model. The procedure could later be interpreted as adding an anti-D4(M5)-brane to the prime N=6 membrane theory, resulting in a N=0 antimembrane theory while other symmetries are preserved. Then, according to the well-known state-operator correspondence rules, we find a proper dual operator with the conformal dimension of Δ+=3 that matches to the bulk massless pseudoscalar state. After that, by making use of some fitting Ansätze for the used matter fields, we arrive at an exact boundary solution and comment on the other related issues as well.
Finite-size effect of η-deformed AdS5 × S5 at strong coupling
NASA Astrophysics Data System (ADS)
Ahn, Changrim
2017-04-01
We compute Lüscher corrections for a giant magnon in the η-deformed (AdS5×S5)η using the su(2 | 2) q-invariant S-matrix at strong coupling and compare with the finite-size effect of the corresponding string state, derived previously. We find that these two results match and confirm that the su(2 | 2) q-invariant S-matrix is describing world-sheet excitations of the η-deformed background.
Joule-Thomson expansion of the charged AdS black holes
NASA Astrophysics Data System (ADS)
Ökcü, Özgür; Aydıner, Ekrem
2017-01-01
In this paper, we study Joule-Thomson effects for charged AdS black holes. We obtain inversion temperatures and curves. We investigate similarities and differences between van der Waals fluids and charged AdS black holes for the expansion. We obtain isenthalpic curves for both systems in the T- P plane and determine the cooling-heating regions.
Effects of ad placement and type on consumer responses to podcast ads.
Ritter, Eric A; Cho, Chang-Hoan
2009-10-01
The purpose of this study was to understand the effects of podcast ad placement and podcast ad type on consumers' perceived intrusiveness, perceived irritation, attitude toward the ad, and ad avoidance. Our 2 x 2 (traditional ad vs. sponsorship by beginning vs. middle) experimental study found that sponsorships generated better consumer responses than did traditional ads and that podcast ads placed at the beginning of audio podcasts yielded better consumer responses than those placed in the middle. Implications for marketers and advertisers are discussed.
Boundary conditions for conformally coupled scalar in AdS4
NASA Astrophysics Data System (ADS)
Oh, Jae-Hyuk
2015-06-01
We consider conformally coupled scalar with ɸ4 coupling in AdS4 and study its various boundary conditions on AdS boundary. We have obtained perturbative solutions of equation of motion of the conformally coupled scalar with power expansion order by order in ɸ4 coupling λ up to λ2 order. In its dual CFT, we get 2, 4 and 6 point functions by using this solution with Dirichlet and Neumann boundary conditions via AdS/CFT dictionary. We also consider marginal deformation on AdS boundary and get its on-shell and boundary effective actions.
Annualized functional change in Alzheimer's disease participants and normal controls.
Weiner, Myron; Fields, Julie; Hynan, Linda; Cullum, C M
2008-09-01
The rate of functional change in persons with mild Alzheimer's disease (AD) was compared to that of cognitively normal elderly control subjects. A comparison of annualized rates of change on the Test of Everyday Functional Abilities (TEFA) was carried out, along with a brief measure of instrumental activities of daily living skills, in persons with mild AD (Mini-Mental State Exam score >20) and cognitively normal elderly controls. Persons with AD (N = 30) showed an 8.5 % (3.5 point) annualized decline in TEFA scores over an average of 1.2 years; there was no decline in a group of elderly normal controls (N = 20) over an average of 1.5 years. Persons with mild AD showed functional changes over the course of a year on a direct measure of instrumental activities of daily living; a comparable group of normally aging persons did not.
Snacks, sweetened beverages, added sugars, and schools.
2015-03-01
Concern over childhood obesity has generated a decade-long reformation of school nutrition policies. Food is available in school in 3 venues: federally sponsored school meal programs; items sold in competition to school meals, such as a la carte, vending machines, and school stores; and foods available in myriad informal settings, including packed meals and snacks, bake sales, fundraisers, sports booster sales, in-class parties, or other school celebrations. High-energy, low-nutrient beverages, in particular, contribute substantial calories, but little nutrient content, to a student's diet. In 2004, the American Academy of Pediatrics recommended that sweetened drinks be replaced in school by water, white and flavored milks, or 100% fruit and vegetable beverages. Since then, school nutrition has undergone a significant transformation. Federal, state, and local regulations and policies, along with alternative products developed by industry, have helped decrease the availability of nutrient-poor foods and beverages in school. However, regular access to foods of high energy and low quality remains a school issue, much of it attributable to students, parents, and staff. Pediatricians, aligning with experts on child nutrition, are in a position to offer a perspective promoting nutrient-rich foods within calorie guidelines to improve those foods brought into or sold in schools. A positive emphasis on nutritional value, variety, appropriate portion, and encouragement for a steady improvement in quality will be a more effective approach for improving nutrition and health than simply advocating for the elimination of added sugars.
Gribov ambiguity in asymptotically AdS three-dimensional gravity
Anabalon, Andres; Canfora, Fabrizio; Giacomini, Alex; Oliva, Julio
2011-03-15
In this paper the zero modes of the de Donder gauge Faddeev-Popov operator for three-dimensional gravity with negative cosmological constant are analyzed. It is found that the AdS{sub 3} vacuum produces (infinitely many) normalizable smooth zero modes of the Faddeev-Popov operator. On the other hand, it is found that the Banados-Teitelboim-Zanelli black hole (including the zero mass black hole) does not generate zero modes. This differs from the usual Gribov problem in QCD where, close to the maximally symmetric vacuum, the Faddeev-Popov determinant is positive definite while 'far enough' from the vacuum it can vanish. This suggests that the zero mass Banados-Teitelboim-Zanelli black hole could be a suitable ground state of three-dimensional gravity with negative cosmological constant. Because of the kinematic origin of this result, it also applies for other covariant gravity theories in three dimensions with AdS{sub 3} as maximally symmetric solution, such as new massive gravity and topologically massive gravity. The relevance of these results for supersymmetry breaking is pointed out.
Puzzles of η-deformed AdS5 × S5
NASA Astrophysics Data System (ADS)
Arutyunov, Gleb; Borsato, Riccardo; Frolov, Sergey
2015-12-01
We derive the part of the Lagrangian for the sigma model on the η-deformed AdS5 × S5 space which is quadratic in fermions and has the full dependence on bosons. We then show that there exists a field redefinition which brings the corresponding La-grangian to the standard form of type IIB Green-Schwarz superstring. Reading off the corresponding RR couplings, we observe that they fail to satisfy the supergravity equations of motion, despite the presence of κ-symmetry. However, in a special scaling limit our solution reproduces the supergravity background found by Maldacena and Russo. Further, using the fermionic Lagrangian, we compute a number of new matrix elements of the tree level world-sheet scattering matrix. We then show that after a unitary transformation on the basis of two-particle states which is not one-particle factorisable, the corresponding T-matrix factorises into two equivalent parts. Each part satisfies the classical Yang-Baxter equation and coincides with the large tension limit of the q-deformed S-matrix.
Complete 1-loop test of AdS/CFT
NASA Astrophysics Data System (ADS)
Gromov, Nikolay; Vieira, Pedro
2008-04-01
We analyze nested Bethe ansatz (NBA) and the corresponding finite size corrections. We find an integral equation which describes these corrections in a closed form. As an application we considered the conjectured Beisert-Staudacher (BS) equations with the Hernandez-Lopez dressing factor where the finite size corrections should reproduce generic one (worldsheet) loop computations around any classical superstring motion in the AdS5 × S5 background with exponential precision in the large angular momentum of the string states. Indeed, we show that our integral equation can be interpreted as a sum over all physical fluctuations and thus prove the complete 1-loop consistency of the BS equations. In other words we demonstrate that any local conserved charge (including the AdS Energy) computed from the BS equations is indeed given at 1-loop by the sum of charges of fluctuations up to exponentially suppressed contributions in the large angular momentum os the string states. We also point out where precisely we loose the exponential terms in our ab initio analysis. Contrary to all previous studies of finite size corrections, which were limited to simple configurations inside rank 1 subsectors, our treatment is completely general.
= 4 supersymmetric Yang-Mills theories in AdS3
NASA Astrophysics Data System (ADS)
Kuzenko, Sergei M.; Tartaglino-Mazzucchelli, Gabriele
2014-05-01
For all types of = 4 anti-de Sitter (AdS) supersymmetry in three dimensions, we construct manifestly supersymmetric actions for Abelian vector multiplets and explain how to extend the construction to the non-Abelian case. Manifestly = 4 supersymmetric Yang-Mills (SYM) actions are explicitly given in the cases of (2,2) and critical (4,0) AdS supersymmetries. The = 4 vector multiplets and the corresponding actions are then reduced to (2,0) AdS superspace, in which only = 2 supersymmetry is manifest. Using the off-shell structure of the = 4 vector multiplets, we provide complete = 4 SYM actions in (2,0) AdS superspace for all types of = 4 AdS supersymmetry. In the case of (4,0) AdS supersymmetry, which admits a Euclidean counterpart, the resulting = 2 action contains a Chern-Simons term proportional to q/r, where r is the radius of AdS 3 and q is the R-charge of a chiral scalar superfield. The R-charge is a linear inhomogeneous function of X, an expectation value of the = 4 Cotton superfield. Thus our results explain the mysterious structure of = 4 supersymmetric Yang-Mills theories on S 3 discovered in arXiv:1401.7952. In the case of (3,1) AdS supersymmetry, which has no Euclidean counterpart, the SYM action contains both a Chern-Simons term and a chiral mass-like term. In the case of (2,2) AdS supersymmetry, which admits a Euclidean counterpart, the SYM action has no Chern-Simons and chiral mass-like terms.
Beyond Test Scores: Adding Value to Assessment
ERIC Educational Resources Information Center
Rothman, Robert
2010-01-01
At a time when teacher quality has emerged as a key factor in student learning, a statistical technique that determines the "value added" that teachers bring to student achievement is getting new scrutiny. Value-added measures compare students' growth in achievement to their expected growth, based on prior achievement and demographic…
Thermodynamic geometry and phase transitions of AdS braneworld black holes
NASA Astrophysics Data System (ADS)
Chaturvedi, Pankaj; Sengupta, Gautam
2017-02-01
The thermodynamics and phase transitions of charged RN-AdS and rotating Kerr-AdS black holes in a generalized Randall-Sundrum braneworld are investigated in the framework of thermodynamic geometry. A detailed analysis of the thermodynamics, stability and phase structures in the canonical and the grand canonical ensembles for these AdS braneworld black holes are described. The thermodynamic curvatures for both these AdS braneworld black holes are computed and studied as a function of the thermodynamic variables. Through this analysis we illustrate an interesting dependence of the phase structures on the braneworld parameter for these black holes.
Next-Generation A/D Sampler ADS3000+ for VLBI2010
NASA Technical Reports Server (NTRS)
Takefuji, Kazuhiro; Takeuchi, Hiroshi; Tsutsumi, Masanori; Koyama, Yasuhiro
2010-01-01
A high-speed A/D sampler, called ADS3000+, has been developed in 2008, which can sample one analog signal up to 4 Gbps to versatile Linux PC. After A/D conversion, the ADS3000+ can perform digital signal processing such as real-time DBBC (Digital Base Band Conversion) and FIR filtering such as simple CW RFI filtering using the installed FPGAs. A 4 Gsps fringe test with the ADS3000+ has been successfully performed. The ADS3000+ will not exclusively be used for VLBI but will also be employed in other applications.
NASA Astrophysics Data System (ADS)
Mazhari, N. S.; Momeni, Davood; Bahamonde, Sebastian; Faizal, Mir; Myrzakulov, Ratbay
2017-03-01
The holographic complexity and fidelity susceptibility have been defined as new quantities dual to different volumes in AdS. In this paper, we will use these new proposals to calculate both of these quantities for a variety of interesting deformations of AdS. We obtain the holographic complexity and fidelity susceptibility for an AdS black hole, Janus solution, a solution with cylindrical symmetry, an inhomogeneous background and a hyperscaling violating background. It is observed that the holographic complexity depends on the size of the subsystem for all these solutions and the fidelity susceptibility does not have any such dependence.
[Rapid analysis of added ingredients in heroin].
Wang, Ji-fen; Yu, Jing; Guo, Xin; Sun, Xing-long; Wang, Ding-fang
2011-07-01
The method of rapid analysis of added ingredients in heroin was studied in the present paper. Adding sucrose, fructose, glucose, starch, caffeine and phenacetin to heroin with a certain percentage, the changes in the infrared spectrum with the concentration of heroin increasing and the detection limit of the additives were determined. Whether or not heroin can be detected in the sample with high concentration of added ingredients was studied using Raman spectroscopy. Similarly, in high purity of heroin, whether or not Raman spectroscopy can detect the added ingredients was tested. Through systematic experiments, the results showed that: using infrared spectroscopy and Raman spectroscopy to test the added ingredients of heroin is a rapid and effective method. Each has both advantages and disadvantages. We should select the appropriate method according to the actual cases.
The eleven observations of comets between 687 AD and 1114 AD recorded in the Anglo Saxon Chronicle
NASA Technical Reports Server (NTRS)
Mardon, E. G.; Williams, J.; Mardon, A. A.
1992-01-01
This research paper is an examination of the eleven cometary references (679AD, 729AD, 892AD, 950AD, 975AD, 995AD, 1066AD, 1097AD, 1106AD, 1110AD and 1114AD) found in the various manuscripts of The Anglo Saxon Chronicle between 678 AD and 1114 AD. The manuscripts contain more than 35 celestial observations. This is an examination of astronomical phenomena and other climatic or natural events, that are described in The Anglo Saxon Chronicle, which is also referred to as The Old English Annals.
Superradiance instability of small rotating AdS black holes in arbitrary dimensions
NASA Astrophysics Data System (ADS)
Delice, Ã.-zgür; Durǧut, Türküler
2015-07-01
We investigate the stability of D dimensional singly rotating Myers-Perry-AdS black holes under superradiance against scalar field perturbations. It is well known that small four dimensional rotating or charged Anti-de Sitter (AdS) black holes are unstable against superradiance instability of a scalar field. Recent works extended the existence of this instability to five dimensional rotating charged AdS black holes or static charged AdS black holes in arbitrary dimensions. In this paper we analytically prove that rotating small AdS black holes in arbitrary dimensions also shows superradiance instability irrespective of the value of the (positive) angular momentum quantum number. To do this we solve the Klein-Gordon equation in the slow rotation, low frequency limit. By using the asymptotic matching technique, we are able to calculate the real and imaginary parts of the correction terms to the frequency of the scalar field due to the presence of the black hole, confirming the presence of superradiance instability. We see that, unlike in the case of static AdS black holes, the analytical method is valid for rotating AdS black holes for any value of angular momentum number and spacetime dimensions. For comparison we derive the corresponding correction terms for Myers-Perry black holes in the black hole bomb formalism in the Appendix and see that the results are in agreement.
ERIC Educational Resources Information Center
Lincove, Jane Arnold; Osborne, Cynthia; Dillon, Amanda; Mills, Nicholas
2014-01-01
Despite questions about validity and reliability, the use of value-added estimation methods has moved beyond academic research into state accountability systems for teachers, schools, and teacher preparation programs (TPPs). Prior studies of value-added measurement for TPPs test the validity of researcher-designed models and find that measuring…
Is School Value Added Indicative of Principal Quality? Working Paper 12. Revised
ERIC Educational Resources Information Center
Chiang, Hanley; Lipscomb, Stephen; Gill, Brian
2014-01-01
States across the country are developing systems for evaluating school principals on the basis of student achievement growth. A common approach is to hold principals accountable for the value added of their schools--that is, schools' contributions to student achievement growth. In theory, school value added can reflect not only principals'…
Space-like minimal surfaces in AdS × S
NASA Astrophysics Data System (ADS)
Dorn, Harald; Drukker, Nadav; Jorjadze, George; Kalousios, Chrysostomos
2010-04-01
We present a four parameter family of classical string solutions in AdS 3 × S 3, which end along a light-like tetragon at the boundary of AdS 3 and carry angular momentum along two cycles on the sphere. The string surfaces are space-like and their projections on AdS 3 and on S 3 have constant mean curvature. The construction is based on the Pohlmeyer reduction of the related sigma model. After embedding in AdS 5 × S 5, we calculate the regularized area and analyze conserved charges. Comments on possible relations to scattering amplitudes are presented. We also sketch time-like versions of our solutions.
Supergravity background of the λ-deformed AdS3 × S3 supercoset
NASA Astrophysics Data System (ADS)
Chervonyi, Yuri; Lunin, Oleg
2016-09-01
We construct the solution of type IIB supergravity describing the integrable λ-deformation of the AdS3 ×S3 supercoset. While the geometry corresponding to the deformation of the bosonic coset has been found in the past, our background is more natural for studying superstrings, and several interesting features distinguish our solution from its bosonic counterpart. We also report progress towards constructing the λ-deformation of the AdS5 ×S5 supercoset.
Nitrini, Ricardo; Caramelli, Paulo; Bottino, Cássio Machado de Campos; Damasceno, Benito Pereira; Brucki, Sonia Maria Dozzi; Anghinah, Renato
2005-09-01
The educational and cultural heterogeneity of the Brazilian population leads to peculiar characteristics regarding the diagnosis of Alzheimer's disease (AD). This consensus had the objective of recommending evidence-based guidelines for the clinical diagnosis of AD in Brazil. Studies on the diagnosis of AD published in Brazil were systematically evaluated in a thorough research of PUBMED and LILACS databases. For global cognitive evaluation, the Mini-Mental State Examination was recommended; for memory evaluation: delayed recall subtest of CERAD or of objects presented as drawings; attention: trail-making or digit-span; language: Boston naming, naming test from ADAS-Cog or NEUROPSI; executive functions: verbal fluency or clock-drawing; conceptualization and abstraction: similarities from CAMDEX or NEUROPSI; construction: drawings from CERAD. For functional evaluation, IQCODE, or Pfeffer Questionnaire or Bayer Scale for Activities of Daily Living was recommended. The panel concluded that the combined use of cognitive and functional evaluation based on interview with informant is recommended.
Punchick, Boris; Freud, Tamar; Press, Yan
2016-01-01
Abstract The prevalence of cognitive impairment and orthostatic hypotension (OH) increases with age, but the results of studies that assessed possible associations between them are inconsistent. The aim of this study is to assess possible associations between cognitive impairment and OH in patients ≥65 years of age who underwent a comprehensive geriatric assessment. A retrospective analysis was conducted of the computerized medical records of the study population from 2005 to 2013. Data collected included blood pressure measurements that enabled the calculation of OH, results of the mini-mental state examination (MMSE), results of the Montreal cognitive assessment (MoCA) test, and cognitive diagnoses that were determined over the course of the assessment. The rate of OH in the study population of 571 adults was 32.1%. The mean MMSE score was 22.5 ± 5.2 among participants with OH and 21.6 ± 5.8 among those without OH (P = 0.09). The absence of a significant association between OH and MMSE remained after adjusting the MMSE score for age and education level. The mean MoCA score was 16.4 ± 5.0 among participants with OH and 16.4 ± 4.8 among those without (P = 0.33). The prevalence of OH was 39% among participants without cognitive impairment, 28.9% among those with mild cognitive impairment (MCI), and 30.6% among those with dementia (P = 0.13). There was no association between OH and cognitive impairment in adults who underwent a comprehensive geriatric assessment. PMID:27442658
Testing the AdS/CFT Correspondence
Klebanov, Igor R.
2008-07-28
This lecture begins with some history and basic facts about string theory and its connections with strong interactions. Comparisons of stacks of Dirichlet branes with curved backgrounds produced by them are used to motivate the AdS/CFT correspondence between superconformal gauge theory and string theory on a product of Anti-de Sitter space and a compact manifold. The ensuing duality between semi-classical spinning strings and long gauge theory operators is briefly reviewed. We go on to describe a recent test of the AdS/CFT correspondence using the Wilson loop cusp anomaly as a function of the coupling, which also enters dimensions of high-spin operators. Finally, strongly coupled thermal SYM theory is explored via a black hole in 5-dimensional AdS space, which leads to explicit results for its entropy and shear viscosity.
The Recent Data Explosion in the ADS
NASA Astrophysics Data System (ADS)
Grant, Carolyn S.; Accomazzi, A.; Henneken, E.; Thompson, D.; Kurtz, M. J.; Murray, S. S.
2007-12-01
In the past 12 months, we have added over a million records to the ADS Abstract Service. This is the equivalent of a 20% increase, or about double the rate of increase that the ADS has seen in recent years. This significant increase in size is due to the addition of several large datasets including historical data from many Springer astronomy and physics journals as well as bibliographic records from the full run of A&A Abstracts from the Astronomisches Rechen-Institut. The number of citations in the Abstract Service has seen an increase of more than 25%, bringing the total number of citations to over 25 million. Our recent agreement to index records from CrossRef will continue the data explosion in the ADS into 2008.
Microbial production of value-added nutraceuticals.
Wang, Jian; Guleria, Sanjay; Koffas, Mattheos A G; Yan, Yajun
2016-02-01
Nutraceuticals are important natural bioactive compounds that confer health-promoting and medical benefits to humans. Globally growing demands for value-added nutraceuticals for prevention and treatment of human diseases have rendered nutraceuticals a multi-billion dollar market. However, supply limitations and extraction difficulties from natural sources such as plants, animals or fungi, restrict the large-scale use of nutraceuticals. Metabolic engineering via microbial production platforms has been advanced as an eco-friendly alternative approach for production of value-added nutraceuticals from simple carbon sources. Microbial platforms like the most widely used Escherichia coli and Saccharomyces cerevisiae have been engineered as versatile cell factories for production of diverse and complex value-added chemicals such as phytochemicals, prebiotics, polysaccaharides and poly amino acids. This review highlights the recent progresses in biological production of value-added nutraceuticals via metabolic engineering approaches.
Adding stress plot function to NASTRAN
NASA Technical Reports Server (NTRS)
Katoh, S.
1978-01-01
Stress plot function was developed and added to the NASTRAN level 15.5. Computed stress distribution can be displayed by this function, with vectors showing the principal stresses of the finite elements over the specified portions of the structure. NASTRAN is reviewed in the aspect of plotting capabilities. Stress tensor field is examined in preparation of stress display. Then the stress plot function as added to the NASTRAN is described. A sample plotout by this function is shown.
ERIC Educational Resources Information Center
Johnston, Anne; Kaid, Lynda Lee
2002-01-01
Explores the differences in techniques, strategies, narratives, and symbols used in 1,213 television issue ads and image ads from 13 U.S. presidential campaigns. Concludes that although the majority of both types of ads were positive, negative appeals dominated a higher percentage of issue ads as compared with image ads. (SG)
AdS5×S(5) mirror model as a string sigma model.
Arutyunov, Gleb; van Tongeren, Stijn J
2014-12-31
Doing a double Wick rotation in the world sheet theory of the light cone AdS5×S(5) superstring results in an inequivalent, so-called mirror theory that plays a central role in the field of integrability in the AdS-CFT correspondence. We show that this mirror theory can be interpreted as the light cone theory of a free string on a different background. This background is related to dS5×H(5) by a double T-duality, and has hidden supersymmetry. The geometry can also be extracted from an integrable deformation of the AdS5×S(5) sigma model, and we prove the observed mirror duality of these deformed models at the bosonic level as a byproduct. While we focus on AdS5×S(5), our results apply more generally.
Light-Front Quantization and AdS/QCD: An Overview
de Teramond, Guy F.; Brodsky, Stanley J.; /SLAC /Stanford U., Phys. Dept.
2011-08-19
We give an overview of the light-front holographic approach to strongly coupled QCD, whereby a confining gauge theory, quantized on the light front, is mapped to a higher-dimensional anti de Sitter (AdS) space. The framework is guided by the AdS/CFT correspondence incorporating a gravitational background asymptotic to AdS space which encodes the salient properties of QCD, such as the ultraviolet conformal limit at the AdS boundary at z {yields} 0, as well as modifications of the geometry in the large z infrared region to describe confinement and linear Regge behavior. There are two equivalent procedures for deriving the AdS/QCD equations of motion: one can start from the Hamiltonian equation of motion in physical space time by studying the off-shell dynamics of the bound state wavefunctions as a function of the invariant mass of the constituents. To a first semiclassical approximation, where quantum loops and quark masses are not included, this leads to a light-front Hamiltonian equation which describes the bound state dynamics of light hadrons in terms of an invariant impact variable {zeta} which measures the separation of the partons within the hadron at equal light-front time. Alternatively, one can start from the gravity side by studying the propagation of hadronic modes in a fixed effective gravitational background. Both approaches are equivalent in the semiclassical approximation. This allows us to identify the holographic variable z in AdS space with the impact variable {zeta}. Light-front holography thus allows a precise mapping of transition amplitudes from AdS to physical space-time. The internal structure of hadrons is explicitly introduced and the angular momentum of the constituents plays a key role.
The relative facts interpretation and Everett's note added in proof
NASA Astrophysics Data System (ADS)
Conroy, Christina
2012-05-01
In the published version of Hugh Everett III's doctoral dissertation, he inserted what has become a famous footnote, the "note added in proof". This footnote is often the strongest evidence given for any of various interpretations of Everett (the many worlds, many minds, many histories and many threads interpretations). In this paper I will propose a new interpretation of the footnote. One that is supported by evidence found in letters written to and by Everett; one that is suggested by a new interpretation of Everett, an interpretation that takes seriously the central position of relative states in Everett's pure wave mechanics: the relative facts interpretation. Of central interest in this paper is how to make sense of Everett's claim in the "note added in proof" that "all elements of a superposition (all "branches") are "actual," none any more "real" than the rest."
Distributed Reinforcement Learning Approach for Vehicular Ad Hoc Networks
NASA Astrophysics Data System (ADS)
Wu, Celimuge; Kumekawa, Kazuya; Kato, Toshihiko
In Vehicular Ad hoc Networks (VANETs), general purpose ad hoc routing protocols such as AODV cannot work efficiently due to the frequent changes in network topology caused by vehicle movement. This paper proposes a VANET routing protocol QLAODV (Q-Learning AODV) which suits unicast applications in high mobility scenarios. QLAODV is a distributed reinforcement learning routing protocol, which uses a Q-Learning algorithm to infer network state information and uses unicast control packets to check the path availability in a real time manner in order to allow Q-Learning to work efficiently in a highly dynamic network environment. QLAODV is favored by its dynamic route change mechanism, which makes it capable of reacting quickly to network topology changes. We present an analysis of the performance of QLAODV by simulation using different mobility models. The simulation results show that QLAODV can efficiently handle unicast applications in VANETs.
Supersymmetric wrapped membranes, AdS2 spaces, and bubbling geometries
NASA Astrophysics Data System (ADS)
MacConamhna, Oisín A. P.; Colgáin, Eoin Ó.
2007-03-01
We perform a systematic study, in eleven dimensional supergravity, of the geometry of wrapped brane configurations admitting AdS2 limits. Membranes wrapping holomorphic curves in Calabi-Yau manifolds are found to exhibit some novel features; in particular, for fourfolds or threefolds, the gravitational effect of the branes on the overall transverse space is only weakly restricted by the kinematics of the Killing spinor equation. We also study the AdS2 limits of the wrapped brane supergravity descriptions. For membranes wrapped in a two-fold, we derive a set of AdS2 supersymmetry conditions which upon analytic continuation coincide precisely with those for the half-BPS bubbling geometries of LLM. From membranes wrapped in a three-fold, we obtain a set of AdS2 supersymmetry conditions which upon analytic continuation describe a class of spacetimes which we identify as quarter-BPS bubbling geometries in M-theory, with SO(4) × SO(3) × U(1) isometry in Riemannian signature. We also study fivebranes wrapping a special lagrangian five-cycle in a fivefold, in the presence of membranes wrapping holomorphic curves, and employ the wrapped brane supersymmetry conditions to derive a classification of the general minimally supersymmetric AdS2 geometry in M-theory.
Implementation of Recursion Relations in Gluon Scattering Amplitude Calculations in AdS4 /CFT3
NASA Astrophysics Data System (ADS)
Dokmetzoglou, Nikolaos; Kharel, Savan
2017-01-01
The Anti-de Sitter/Conformal Field Theory (AdS/CFT) correspondence is a duality between a theory of gravity in curved-space (AdS) and a conformally-invariant quantum field theory in flat-space (CFT). Scattering amplitudes are observables associated with the probability of the interaction of a given assembly of particles. Gluons, being the exchange particles associated with the strong nuclear force, which holds quarks together to form protons, are abundant byproducts of fundamental particle collisions. Thus, studying gluon scattering amplitudes is an effective way of deepening our understanding of these observables in AdS/CFT. Traditionally, Feynman diagrams have been used to calculate such scattering amplitudes. In this project, we use factorization properties and recursion relations to simplify these calculations. More specifically, we calculate multiple (different helicity combinations) four-point gluon scattering amplitudes in AdS4 /CFT3 (4-D AdS and 3-D CFT) as sums of products of three-point amplitudes. And then we calculate a five-point gluon scattering amplitude in AdS4 /CFT3 by decomposing it into a sum of products of these four-point and three-point amplitudes. Finally we comment on useful identities for checking these amplitudes. This work was supported by a Weinstein Davidson College Research Initiative Summer Research grant.
Efficacy of adding folic acid to foods.
Fajardo, Violeta; Varela-Moreiras, Gregorio
2012-06-01
In the past, food fortification along with nutritional education and the decrease in food costs relative to income have proven successful in eliminating common nutritional deficiencies. These deficiencies such as goiter, rickets, beriberi, and pellagra have been replaced with an entirely new set of "emergent deficiencies" that were not previously considered a problem [e.g., folate and neural tube defects (NTDs)]. In addition, the different nutrition surveys in so-called affluent countries have identified "shortfalls" of nutrients specific to various age groups and/or physiological status. Complex, multiple-etiology diseases, such as atherosclerosis, diabetes, cancer, and obesity have emerged. Food fortification has proven an effective tool for tackling nutritional deficiencies in populations; but today a more reasonable approach is to use food fortification as a means to support but not replace dietary improvement strategies (i. e. nutritional education campaigns). Folic acid (FA) is a potential relevant factor in the prevention of a number of pathologies. The evidence linking FA to NTD prevention led to the introduction of public health strategies to increase folate intakes: pharmacological supplementation, mandatory or voluntary fortification of staple foods with FA, and the advice to increase the intake of folate-rich foods. It is quite contradictory to observe that, regardless of these findings, there is only limited information on food folate and FA content. Data in Food Composition Tables and Databases are scarce or incomplete. Fortification of staple foods with FA has added difficulty to this task. Globally, the decision to fortify products is left up to individual food manufacturers. Voluntary fortification is a common practice in many countries. Therefore, the "worldwide map of vitamin fortification" may be analyzed. It is important to examine if fortification today really answers to vitamin requirements at different ages and/or physiological states. The
Interpolated Sounding and Gridded Sounding Value-Added Products
M. P. Jensen; Toto, T.
2016-03-01
Standard Atmospheric Radiation Measurement (ARM) Climate Research Facility sounding files provide atmospheric state data in one dimension of increasing time and height per sonde launch. Many applications require a quick estimate of the atmospheric state at higher time resolution. The INTERPOLATEDSONDE (i.e., Interpolated Sounding) Value-Added Product (VAP) transforms sounding data into continuous daily files on a fixed time-height grid, at 1-minute time resolution, on 332 levels, from the surface up to a limit of approximately 40 km. The grid extends that high so the full height of soundings can be captured; however, most soundings terminate at an altitude between 25 and 30 km, above which no data is provided. Between soundings, the VAP linearly interpolates atmospheric state variables in time for each height level. In addition, INTERPOLATEDSONDE provides relative humidity scaled to microwave radiometer (MWR) observations.
Photon gas thermodynamics in dS and AdS momentum spaces
NASA Astrophysics Data System (ADS)
Gorji, M. A.; Hosseinzadeh, V.; Nozari, K.; Vakili, B.
2016-07-01
In this paper, we study thermostatistical properties of a photon gas in the framework of two deformed special relativity models defined by the cosmological coordinatizations of the de Sitter (dS) and anti-de Sitter (AdS) momentum spaces. The dS model is a doubly special relativity theory in which an ultraviolet length scale is invariant under the deformed Lorentz transformations. For the case of the AdS model, however, the Lorentz symmetry breaks at the high energy regime. We show that the existence of a maximal momentum in dS momentum space leads to maximal pressure and temperature at the thermodynamical level, while maximal internal energy and entropy arise for the case of the AdS momentum space due to the existence of a maximal kinematical energy. These results show that the thermodynamical duality of these models is very similar to their well-known kinematical duality.
Black hole microstates in AdS4 from supersymmetric localization
NASA Astrophysics Data System (ADS)
Benini, Francesco; Hristov, Kiril; Zaffaroni, Alberto
2016-05-01
This paper addresses a long standing problem, the counting of the microstates of supersymmetric asymptotically AdS black holes in terms of a holographically dual field theory. We focus on a class of asymptotically AdS4 static black holes preserving two real supercharges which are dual to a topologically twisted deformation of the ABJM theory. We evaluate in the large N limit the topologically twisted index of the ABJM theory and we show that it correctly reproduces the entropy of the AdS4 black holes. An extremization of the index with respect to a set of chemical potentials is required. We interpret it as the selection of the exact R-symmetry of the superconformal quantum mechanics describing the horizon of the black hole.
A note on vectorial AdS5/CFT4 duality for spin- j boundary theory
NASA Astrophysics Data System (ADS)
Bae, Jin-Beom; Joung, Euihun; Lal, Shailesh
2016-12-01
The vectorial holographic correspondences between higher-spin theories in AdS5 and free vector models on the boundary are extended to the cases where the latter is described by free massless spin- j field. The dual higher-spin theory in the bulk does not include gravity and can only be defined on rigid AdS5 background with S 4 boundary. We discuss various properties of these rather special higher-spin theories and calculate their one-loop free energies. We show that the result is proportional to the same quantity for spin- j doubleton treated as if it is a AdS5 field. Finally, we consider even more special case where the boundary theory itself is given by an infinite tower of massless higher-spin fields.
QCD Condensates and Holographic Wilson Loops for Asymptotically AdS Spaces
Quevedo, R. Carcasses; Goity, Jose L.; Trinchero, Roberto C.
2014-02-01
The minimization of the Nambu-Goto (NG) action for a surface whose contour defines a circular Wilson loop of radius a placed at a finite value of the coordinate orthogonal to the border is considered. This is done for asymptotically AdS spaces. The condensates of dimension n = 2, 4, 6, 8, and 10 are calculated in terms of the coefficients in the expansion in powers of the radius a of the on-shell subtracted NG action for small a->0. The subtraction employed is such that it presents no conflict with conformal invariance in the AdS case and need not introduce an additional infrared scale for the case of confining geometries. It is shown that the UV value of the gluon condensates is universal in the sense that it only depends on the first coefficients of the difference with the AdS case.
Stability of warped AdS3 vacua of topologically massive gravity
NASA Astrophysics Data System (ADS)
Anninos, Dionysios; Esole, Mboyo; Guica, Monica
2009-10-01
AdS3 vacua of topologically massive gravity (TMG) have been shown to be perturbatively unstable for all values of the coupling constant except the chiral point μl = 1. We study the possibility that the warped vacua of TMG, which exist for all values of μ, are stable under linearized perturbations. In this paper, we show that spacelike warped AdS3 vacua with Compère-Detournay boundary conditions are indeed stable in the range μl>3. This is precisely the range in which black hole solutions arise as discrete identifications of the warped AdS3 vacuum. The situation somewhat resembles chiral gravity: although negative energy modes do exist, they are all excluded by the boundary conditions, and the perturbative spectrum solely consists of boundary (pure large gauge) gravitons.
Consumption of added sugar among U.S. children and adolescents, 2005-2008.
Ervin, R Bethene; Kit, Brian K; Carroll, Margaret D; Ogden, Cynthia L
2012-03-01
Approximately 16% of children and adolescents’ total caloric intakes came from added sugars. Boys consumed more added sugars than girls. Preschool-aged children consumed the fewest calories from added sugars. Although girls consumed a smaller absolute amount of calories from added sugars than boys, their intakes were not that different from boys when the amounts are expressed as a percentage of total caloric intakes. Non-Hispanic white children and adolescents consumed a larger percentage of their calories from added sugars than Mexican-American children and adolescents. Also, Non-Hispanic black girls consumed a larger percentage of their calories from added sugars than Mexican-American girls. There was very little difference in added sugar consumption based on PIR. More of the added sugars calories came from foods as opposed to beverages. Previous research has demonstrated that sodas are the single leading food source of added sugars intakes among children, adolescents, and adults (2,4). Our results showed a little more than 40% of calories from added sugars came from beverages. Poti and Popkin (5) have suggested that eating location impacts daily energy intake in children and adolescents and that foods prepared away from home, are contributing to their increased total energy intake. Our results showed that more of the added sugars calories were consumed at home rather than away from home. A substantial percentage of calories in the diets of children and adolescents between 2005 and 2008 came from added sugars. According to the 2010 Dietary Guidelines "reducing the consumption of these sources of added sugars will lower the caloric content of the diet, without compromising its nutrient adequacy (3)." This strategy could play an important role in reducing the high prevalence of obesity in the United States (6) without compromising adequate nutrition.
The AdS3 × S3 × S3 × S1 worldsheet S matrix
NASA Astrophysics Data System (ADS)
Borsato, Riccardo; Ohlsson Sax, Olof; Sfondrini, Alessandro; Stefański, Bogdan, Jr.
2015-10-01
We investigate type IIB strings on {{{AdS}}}3× {{{S}}}3× {{{S}}}3× {{{S}}}1 with mixed Ramond-Ramond and Neveu-Schwarz-Neveu-Schwarz flux. By suitably gauge-fixing the closed string Green-Schwarz action of this theory, we derive the off-shell symmetry algebra and its representations. We use these to determine the non-perturbative worldsheet S matrix of fundamental excitations in the theory. The analysis involves both massive and massless modes in complete generality. The S matrix we find involves a number of phase factors, which in turn satisfy crossing equations that we also determine. We comment on the nature of the heaviest modes of the theory, but leave their identification either as composites or bound-states to a future investigation.
The generalization of charged AdS black hole specific volume and number density
NASA Astrophysics Data System (ADS)
Wang, Zi-Liang; He, Miao; Fang, Chao; Sun, Dao-Quan; Deng, Jian-Bo
2017-04-01
In this paper, by proposing a generalized specific volume, we restudy the P- V criticality of charged AdS black holes in the extended phase space. The results show that most of the previous conclusions can be generalized without change, but the ratio {\\tilde{ρ }}_c should be 3 {\\tilde{α }}/16 in general case. Further research on the thermodynamical phase transition of black hole leads us to a natural interpretation of our assumption, and more black hole properties can be generalized. Finally, we study the number density for charged AdS black hole in higher dimensions, the results show the necessity of our assumption.
Warped AdS3 , dS3 , and flows from N =(0 ,2 ) SCFTs
NASA Astrophysics Data System (ADS)
O'Colgáin, Eoin
2015-05-01
We present the general form of all timelike supersymmetric solutions to three-dimensional U (1 )3 gauged supergravity, a known consistent truncation of string theory. We uncover a rich vacuum structure, including an infinite class of new timelike-warped AdS3 (Gödel) and timelike-warped dS3 critical points. We outline the construction of supersymmetric flows, driven by irrelevant scalar operators in the SCFT, which interpolate between critical points. For flows from AdS3 to Gödel, the natural candidate for the central charge decreases along the flow. Flows to timelike-warped dS3 exhibit topology change.
Reece, Matthew
2011-05-23
In this talk I give a brief assessment of the 'AdS/QCD correspondence', its successes, and its failures. I begin with a review of the AdS/CFT correspondence, with an emphasis on why the large N, large 't Hooft coupling limit is necessary for a calculable theory. I then briefly discuss attempts to extrapolate this correspondence to QCD-like theories, stressing why the failure of the large 't Hooft coupling limit is more important than the breakdown of the large N expansion. I sketch how event shapes can manifest stringy physics, and close with some brief remarks on the prospects for future improvements.
Advanced Optical A/D Converter
1993-05-01
before the receiver and separately by reducing the gain in the EDFA . It is important to note that the optical power level was varied while all the...could not exceed roughly 50% of the maximum power available at full gain from the EDFA . 4.2 Baseband-Mode Testing The single-channel system was also...AD-A275 663 Advanced Optical A/D Convert M.C. Hamilton, J.A. Bell, D.A. Leep, J.P. Lin The Boeing Company Boeing Defense and Space Group P.O. Box
Added sugar intake and cardiovascular diseases mortality among US adults.
Yang, Quanhe; Zhang, Zefeng; Gregg, Edward W; Flanders, W Dana; Merritt, Robert; Hu, Frank B
2014-04-01
IMPORTANCE Epidemiologic studies have suggested that higher intake of added sugar is associated with cardiovascular disease (CVD) risk factors. Few prospective studies have examined the association of added sugar intake with CVD mortality. OBJECTIVE To examine time trends of added sugar consumption as percentage of daily calories in the United States and investigate the association of this consumption with CVD mortality. DESIGN, SETTING, AND PARTICIPANTS National Health and Nutrition Examination Survey (NHANES, 1988-1994 [III], 1999-2004, and 2005-2010 [n = 31,147]) for the time trend analysis and NHANES III Linked Mortality cohort (1988-2006 [n = 11 733]), a prospective cohort of a nationally representative sample of US adults for the association study. MAIN OUTCOMES AND MEASURES Cardiovascular disease mortality. RESULTS Among US adults, the adjusted mean percentage of daily calories from added sugar increased from 15.7% (95% CI, 15.0%-16.4%) in 1988-1994 to 16.8% (16.0%-17.7%; P = .02) in 1999-2004 and decreased to 14.9% (14.2%-15.5%; P < .001) in 2005-2010. Most adults consumed 10% or more of calories from added sugar (71.4%) and approximately 10% consumed 25% or more in 2005-2010. During a median follow-up period of 14.6 years, we documented 831 CVD deaths during 163,039 person-years. Age-, sex-, and race/ethnicity-adjusted hazard ratios (HRs) of CVD mortality across quintiles of the percentage of daily calories consumed from added sugar were 1.00 (reference), 1.09 (95% CI, 1.05-1.13), 1.23 (1.12-1.34), 1.49 (1.24-1.78), and 2.43 (1.63-3.62; P < .001), respectively. After additional adjustment for sociodemographic, behavioral, and clinical characteristics, HRs were 1.00 (reference), 1.07 (1.02-1.12), 1.18 (1.06-1.31), 1.38 (1.11-1.70), and 2.03 (1.26-3.27; P = .004), respectively. Adjusted HRs were 1.30 (95% CI, 1.09-1.55) and 2.75 (1.40-5.42; P = .004), respectively, comparing participants who consumed 10.0% to 24.9% or 25.0% or
Ad lib caffeine consumption, symptoms of caffeinism, and academic performance.
Gilliland, K; Andress, D
1981-04-01
The authors explored the relationship between ad lib caffeine consumption in college students and the incidence of caffeinism, characterized by heightened anxiety, depression, and various psychophysiological reactions. Students were randomly selected from four groups (abstainers from caffeine and low, moderate, and high consumers). A survey battery assessed the effects of caffeine, incidence of psychophysiological disorders, state-trait anxiety, and depression. The moderate and high consumer groups combined reported significantly higher trait anxiety and depression scores when compared with abstainers. The high consumer group also reported significantly higher levels of symptoms of caffeinism, higher frequency of psychophysiological disorders, and lower academic performance.
Value-added logistics: the answer to mass customization.
Verwoerd, W
1999-11-01
Value added logistics: A new concept or just new terminology? If you read Today and Tomorrow you will notice that Henry Ford used postponed manufacturing to save on transportation costs: On one railway-wagon he could ship either three T-Fords or the parts for seven T-Fords. This is one of the reasons he build several assembly plants in the United States and in Europe (Dagenham, UK; Koln, Germany; and Amsterdam). Although this concept has existed for more than 70 years, I found out that it is still quite unknown. Thanks to information technology, it is becoming more powerful. This opens large possibilities for mass customization.
Total, Added, and Free Sugars: Are Restrictive Guidelines Science-Based or Achievable?
Erickson, Jennifer; Slavin, Joanne
2015-01-01
Sugar consumption, especially added sugars, is under attack. Various government and health authorities have suggested new sugar recommendations and guidelines as low as 5% of total calories from free sugars. Definitions for total sugars, free sugars, and added sugars are not standardized, nor are there accepted nutrient databases for this information. Our objective was to measure total sugars and added sugars in sample meal plans created by the United States Department of Agriculture (USDA) and the Academy of Nutrition and Dietetics (AND). Utilizing the Nutrition Data System for Research (NDSR) nutritional database, results found that plans created by the USDA and AND averaged 5.1% and 3.1% calories from added sugar, 8.7% and 3.1% from free sugar, and 23.3% and 21.1% as total sugars respectively. Compliance with proposed added sugar recommendations would require strict dietary compliance and may not be sustainable for many Americans. Without an accepted definition and equation for calculating added sugar, added sugar recommendations are arbitrary and may reduce intakes of nutrient-rich, recommended foods, such as yogurt, whole grains, and tart fruits including cranberries, cherries, and grapefruit. Added sugars are one part of excess calorie intake; however, compliance with low added sugar recommendations may not be achievable for the general public. PMID:25884659
Miranda, Luís F J R; Gomes, Karina B; Tito, Pedro A L; Silveira, Josianne N; Pianetti, Gerson A; Byrro, Ricardo M D; Peles, Patrícia R H; Pereira, Fernando H; Santos, Thiago R; Assini, Arthur G; Ribeiro, Valéria V; Moraes, Edgar N; Caramelli, Paulo
2017-01-01
The clinical response to donepezil in patients with mild and moderate dementia was investigated in relation to the drug plasma concentration and APOE and CYP2D6 polymorphisms. In a prospective naturalistic observational study, 42 patients with Alzheimer's disease (AD) and AD with cerebrovascular disease who took donepezil (10 mg) for 12 months were evaluated. Their DNA was genotyped, and the donepezil plasma concentrations were measured after 3, 6, and 12 months. Good responders scored ≥-1 on the Mini-Mental State Examination at 12 months in comparison to the baseline score. The study results indicated the good response pattern was influenced by the concentration of donepezil, but not by APOE and CYP2D6 polymorphisms.
Park, Hyunjin
2012-04-04
Neuroimaging data are high dimensional and thus cumbersome to analyze. Manifold learning is a technique to find a low dimensional representation for high dimensional data. With manifold learning, data analysis becomes more tractable in the low dimensional space. We propose a novel shape quantification method based on a manifold learning method, ISOMAP, for brain MRI. Existing work applied another manifold learning method, multidimensional scaling (MDS), to quantify shape information for distinguishing Alzheimer's disease (AD) from normal. We enhance the existing methodology by (1) applying it to distinguish mild cognitive impairment (MCI) from normal, (2) adopting a more advanced manifold learning technique, ISOMAP, and (3) showing the effectiveness of the induced low dimensional embedding space to predict key clinical variables such as mini mental state exam scores and clinical diagnosis using the standard multiple linear regression. Our methodology was tested using 25 normal, 25 AD, and 25 MCI patients.
Cholinesterase inhibitors in Alzheimer's disease: efficacy in a non-selected population.
Sinforiani, Elena; Banchieri, Lara Maria; Zucchella, Chiara; Bernasconi, Luca; Nappi, Giuseppe
2003-01-01
This paper presents preliminary results on the efficacy of acetyl-cholinesterase inhibitors (ChE-I) administered in a population of patients with mild-to-moderate Alzheimer's disease (AD), recruited in the context of an Italian Department of Health supported project (Progetto Cronos). The patients were followed up for a maximum of 21 months. Around 45% of the subjects responded well to the treatment (i.e., stable or improved Mini Mental State) at the end of the 9th month. Thereafter, a global cognitive and functional decline was reported, more marked in basic daily activities. No factors (age, sex, disease duration, family history for AD, cognitive impairment at baseline) emerged as predictors of outcome.
The AD Nurse: Prepared to be Prepared
ERIC Educational Resources Information Center
Beverly, Lynne; Junker, Mary H.
1977-01-01
It is not enough for the new associate degree (AD) nursing graduate to know the theory and be willing to learn. She must also have some skill in providing basic nursing care. Examples of applicants, both ADNs and BSNs, are described to illustrate the nursing talent necessary to practice sensitively and effectively. (Editor/TA)
Value-Added Analysis in Instruction
ERIC Educational Resources Information Center
Nicholson, Michael R.; Brown, Jeffrey R.
2010-01-01
Value-added data provide a viable alternative for gauging school effectiveness--one virtually free of the confounding effects of student demographics and other factors relating to student learning. How is it different from other measuring methods? It concentrates on growth, rather than attainment. This strengthens the concept and measurement of…
Adding calcium improves lithium ferrite core
NASA Technical Reports Server (NTRS)
Lessoff, H.
1969-01-01
Adding calcium increases uniformity of grain growth over a wide range of sintering temperatures and reduces porosity within the grain. Ferrite cores containing calcium have square hysteresis loops and high curie temperatures, making them useful in coincident current memories of digital electronic computers.
Higher Education Value Added Using Multiple Outcomes
ERIC Educational Resources Information Center
Milla, Joniada; Martín, Ernesto San; Van Bellegem, Sébastien
2016-01-01
In this article we develop a methodology for the joint value added analysis of multiple outcomes that takes into account the inherent correlation between them. This is especially crucial in the analysis of higher education institutions. We use a unique Colombian database on universities, which contains scores in five domains tested in a…
Adding Users to the Website Design Process
ERIC Educational Resources Information Center
Tomeo, Megan L.
2012-01-01
Alden Library began redesigning its website over a year ago. Throughout the redesign process the students, faculty, and staff that make up the user base were added to the conversation by utilizing several usability test methods. This article focuses on the usability testing conducted at Alden Library and delves into future usability testing, which…
Gubser, Steven S.
2006-12-15
The AdS/CFT correspondence and a classical test string approximation are used to calculate the drag force on an external quark moving in a thermal plasma of N=4 super-Yang-Mills theory. This computation is motivated by the phenomenon of jet-quenching in relativistic heavy ion collisions.
Value Added School Review Field Guide
ERIC Educational Resources Information Center
Alberta Education, 2009
2009-01-01
The "Value-Added School Review (VSR)" is an analytical model designed to assist schools in identifying and addressing opportunities for school improvement. The model works best when it is focused purposefully on students and the student learning outcomes as defined in the "Guide to Education". It complements the processes…
Imago Mundi, Imago AD, Imago ADNI
2014-01-01
Since the launch in 2003 of the Alzheimer’s Disease Neuroimaging Initiative (ADNI) in the USA, ever growing, similarly oriented consortia have been organized and assembled around the world. The various accomplishments of ADNI have contributed substantially to a better understanding of the underlying physiopathology of aging and Alzheimer’s disease (AD). These accomplishments are basically predicated in the trinity of multimodality, standardization and sharing. This multimodality approach can now better identify those subjects with AD-specific traits that are more likely to present cognitive decline in the near future and that might represent the best candidates for smaller but more efficient therapeutic trials – trials that, through gained and shared knowledge, can be more focused on a specific target or a specific stage of the disease process. In summary, data generated from ADNI have helped elucidate some of the pathophysiological mechanisms underpinning aging and AD pathology, while contributing to the international effort in setting the groundwork for biomarker discovery and establishing standards for early diagnosis of AD. PMID:25478022
ERIC Educational Resources Information Center
Karpatkin, Rhoda H.; Holmes, Anita
1995-01-01
Advertisers spend billions to market so-called educational products, services, and viewpoints to vulnerable young consumers. Budget constraints are forcing educators to accept ads and promotional materials. Several education and consumer-interest groups are developing guidelines for using commercial materials in schools. Consumers Union developed…
Cutting Budget Corners While Adding Value.
ERIC Educational Resources Information Center
Veile, Craig N.; Carpenter, Mark J.
2000-01-01
Discusses how one school district saved money while adding long- term value to its capital improvement project. Planning issues involving square footage requirements, quality of material to be used, and heating and cooling system selection are discussed as are concepts to increase student learning capacity for the same construction dollars. (GR)
Test Scaling and Value-Added Measurement
ERIC Educational Resources Information Center
Ballou, Dale
2009-01-01
Conventional value-added assessment requires that achievement be reported on an interval scale. While many metrics do not have this property, application of item response theory (IRT) is said to produce interval scales. However, it is difficult to confirm that the requisite conditions are met. Even when they are, the properties of the data that…
Distribution of Information in Ad Hoc Networks
2007-09-01
INTENTIONALLY LEFT BLANK v ABSTRACT Ad-hoc networks are distributed, self-organized networks which do not need a fixed infrastructure. Entities in...73 V . CONCLUSIONS AND FUTURE WORK ............................75 A. OVERVIEW ..........................................75 B. CONCLUSIONS...statistical analysis on the results. Finally, Chapter V concludes the research and provides suggestions for further research. 7 II. BACKGROUND A
"Value Added" Gauge of Teaching Probed
ERIC Educational Resources Information Center
Viadero, Debra
2009-01-01
A new study by a public and labor economist suggests that "value added" methods for determining the effectiveness of classroom teachers are built on some shaky assumptions and may be misleading. The study, due to be published in February in the "Quarterly Journal of Economics," is the first of a handful of papers now in the…
Anomaly Detection Techniques for Ad Hoc Networks
ERIC Educational Resources Information Center
Cai, Chaoli
2009-01-01
Anomaly detection is an important and indispensable aspect of any computer security mechanism. Ad hoc and mobile networks consist of a number of peer mobile nodes that are capable of communicating with each other absent a fixed infrastructure. Arbitrary node movements and lack of centralized control make them vulnerable to a wide variety of…
Adding Test Generation to the Teaching Machine
ERIC Educational Resources Information Center
Bruce-Lockhart, Michael; Norvell, Theodore; Crescenzi, Pierluigi
2009-01-01
We propose an extension of the Teaching Machine project, called Quiz Generator, that allows instructors to produce assessment quizzes in the field of algorithm and data structures quite easily. This extension makes use of visualization techniques and is based on new features of the Teaching Machine that allow third-party visualizers to be added as…
Hairy black holes and the endpoint of AdS4 charged superradiance
NASA Astrophysics Data System (ADS)
Dias, Óscar J. C.; Masachs, Ramon
2017-02-01
We construct hairy black hole solutions that merge with the anti-de Sitter (AdS4) Reissner-Nordström black hole at the onset of superradiance. These hairy black holes have, for a given mass and charge, higher entropy than the corresponding AdS4-Reissner-Nordström black hole. Therefore, they are natural candidates for the endpoint of the charged superradiant instability. On the other hand, hairy black holes never dominate the canonical and grand-canonical ensembles. The zero-horizon radius of the hairy black holes is a soliton (i.e. a boson star under a gauge transformation). We construct our solutions perturbatively, for small mass and charge, so that the properties of hairy black holes can be used to testify and compare with the endpoint of initial value simulations. We further discuss the near-horizon scalar condensation instability which is also present in global AdS4-Reissner-Nordström black holes. We highlight the different nature of the near-horizon and superradiant instabilities and that hairy black holes ultimately exist because of the non-linear instability of AdS.
Measuring the Value Added of Management: A Knowledge Value Added Approach
2007-04-30
Value Added Approach Presenter: Dr. Thomas J. Housel specializes in valuing intellectual capital , telecommunications, information technology, value...Value-Added methodology for objectively measuring the return generated by corporate knowledge assets/ intellectual capital . He received his PhD...measuring the value of intellectual capital has been featured in a Fortune cover story (October 3, 1994) and Investor’s Business Daily, numerous books
Holographic Hydrodynamics with Baryon Chemical Potential for Charged AdS Black Hole
Takeuchi, Shingo
2009-12-15
We work out the decoupling problem and hydrodynamic analysis for the sound mode in charged AdS black hole and calculate the sound velocity, the charge susceptibility and the electrical conductivity. We find that Einstein relation among the conductivity, the diffusion constant and the susceptibility holds exactly.
Thermodynamics and Stability of Five Dimensional AdS Reissner-Nordstrom Black Hole
NASA Astrophysics Data System (ADS)
Saadat, Hassan
2012-01-01
In this paper we consider five dimensional AdS Reissner-Nordstrom black hole and calculate thermodynamical variables such as entropy, specific heat and free energy. In that case we can obtain stability conditions of the black hole and fix black hole charge and mass for phase transition.
Avoiding Ad Avoidance: Factors Affecting the Perception of Online Banner Ads
ERIC Educational Resources Information Center
Portnoy, Felix
2012-01-01
This dissertation examined the effect of search type, ad saliency, and ad repetition on the perception of online banner advertisements. In the first study, 48 student participants conducted simulated search tasks using mixed factorial design where search type (known-item vs. exploratory) was manipulated within-subject and the banner saliency level…
Master symmetry in the AdS 5 × S 5 pure spinor string
NASA Astrophysics Data System (ADS)
Chandía, Osvaldo; Linch, William Divine; Vallilo, Brenno Carlini
2017-01-01
We lift the set of classical non-local symmetries recently studied by Klose, Loebbert, and Münkler in the context of ℤ 2 cosets to the pure spinor description of the superstring in the AdS 5 × S 5 background.
Integrable deformation of the AdS5×S5 superstring action.
Delduc, F; Magro, M; Vicedo, B
2014-02-07
An integrable deformation of the type IIB AdS5×S5 superstring action is presented. The deformed field equations, Lax connection, and κ-symmetry transformations are given. The original psu(2,2|4) symmetry is expected to become q deformed.
D-branes from pure spinor superstring in AdS5 × S5 background
NASA Astrophysics Data System (ADS)
Hanazawa, Sota; Sakaguchi, Makoto
2017-01-01
We examine the surface term for the BRST transformation of the open pure spinor superstring in an AdS5 ×S5 background. We find that the boundary condition to eliminate the surface term leads to a classification of possible configurations of 1/2 supersymmetric D-branes.
Partition functions in even dimensional AdS via quasinormal mode methods
NASA Astrophysics Data System (ADS)
Keeler, Cynthia; Ng, Gim Seng
2014-06-01
In this note, we calculate the one-loop determinant for a massive scalar (with conformal dimension Δ) in even-dimensional AdS d+1 space, using the quasinormal mode method developed in [1] by Denef, Hartnoll, and Sachdev. Working first in two dimensions on the related Euclidean hyperbolic plane H 2, we find a series of zero modes for negative real values of Δ whose presence indicates a series of poles in the one-loop partition function Z(Δ) in the Δ complex plane; these poles contribute temperature-independent terms to the thermal AdS partition function computed in [1]. Our results match those in a series of papers by Camporesi and Higuchi, as well as Gopakumar et al. [2] and Banerjee et al. [3]. We additionally examine the meaning of these zero modes, finding that they Wick-rotate to quasinormal modes of the AdS2 black hole. They are also interpretable as matrix elements of the discrete series representations of SO(2, 1) in the space of smooth functions on S 1. We generalize our results to general even dimensional AdS2 n , again finding a series of zero modes which are related to discrete series representations of SO(2 n, 1), the motion group of H 2 n .
Geometry and supersymmetry of heterotic warped flux AdS backgrounds
NASA Astrophysics Data System (ADS)
Beck, S.; Gutowski, J.; Papadopoulos, G.
2015-07-01
We classify the geometries of the most general warped, flux AdS backgrounds of heterotic supergravity up to two loop order in sigma model perturbation theory. We show under some mild assumptions that there are no AdS n backgrounds with n ≠ 3. Moreover the warp factor of AdS3 backgrounds is constant, the geometry is a product AdS 3 × M 7 and such solutions preserve, 2, 4, 6 and 8 supersymmetries. The geometry of M 7 has been specified in all cases. For 2 supersymmetries, it has been found that M 7 admits a suitably restricted G 2 structure. For 4 supersymmetries, M 7 has an SU(3) structure and can be described locally as a circle fibration over a 6-dimensional KT manifold. For 6 and 8 supersymmetries, M 7 has an SU(2) structure and can be described locally as a S 3 fibration over a 4-dimensional manifold which either has an anti-self dual Weyl tensor or a hyper-Kähler structure, respectively. We also demonstrate a new Lichnerowicz type theorem in the presence of α' corrections.
Black hole formation in AdS Einstein-Gauss-Bonnet gravity
NASA Astrophysics Data System (ADS)
Deppe, Nils; Kolly, Allison; Frey, Andrew R.; Kunstatter, Gabor
2016-10-01
AdS spacetime has been shown numerically to be unstable against a large class of arbitrarily small perturbations. In [1], the authors presented a preliminary study of the effects on stability of changing the local dynamics by adding a Gauss-Bonnet term to the Einstein action. Here we provide further details as well as new results with improved numerical methods. In particular, we elucidate new structure in Choptuik scaling plots. We also provide evidence of chaotic behavior at the transition between immediate horizon formation and horizon formation after the matter pulse reflects from the AdS conformal boundary. Finally, we present data suggesting the formation of naked singularities in spacetimes with ADM mass below the algebraic bound for black hole formation.
State Online College Job Market: Ranking the States
ERIC Educational Resources Information Center
Carnevale, Anthony; Jayasundera, Tamara; Repnikov, Dmitri; Gulish, Artem
2015-01-01
"State Online College Job Market: Ranking the States" analyzes the online college labor market on a state-by-state basis. We examine the geographic distribution of online job ads for college graduates within industries and occupational clusters, and compare the relative strength of the online college labor market across states. We…
Iyer, Ramakrishnan; Mukhopadhyay, Ayan
2010-04-15
The AdS/CFT correspondence defines a sector with universal strongly coupled dynamics in the field theory as the dual of pure gravity in AdS described by Einstein's equation with a negative cosmological constant. We explain here, from the field-theoretic viewpoint how the dynamics in this sector gets determined by the expectation value of the energy-momentum tensor alone. We first show that the Boltzmann equation has very special solutions which could be functionally completely determined in terms of the energy-momentum tensor alone. We call these solutions conservative solutions. We indicate why conservative solutions should also exist when we refine this kinetic description to go closer to the exact microscopic theory or even move away from the regime of weak coupling so that no kinetic description could be employed. We argue that these conservative solutions form the universal sector dual to pure gravity at strong coupling and large N. Based on this observation, we propose a regularity condition on the energy-momentum tensor so that the dual solution in pure gravity has a smooth future horizon. We also study if irreversibility emerges only at long time scales of observation, unlike the case of the Boltzmann equation.
Effect of Adding on the Critical Current Density and Lateral Levitation Force of Bulk
NASA Astrophysics Data System (ADS)
Savaşkan, B.; Koparan, E. Taylan; Güner, S. B.; Çelik, Ş.; Öztürk, K.; Yanmaz, E.
2015-10-01
We fabricated malic acid -added bulks by wet mixing and "Two-step solid state reaction method". The effects of adding malic acid on , behaviour and lateral levitation force features of bulk have been investigated. A systematic decrease in the critical temperature with increasing adding level confirms the substitution of C at the B site of . While the 4 wt% sample showed the best of at 4 T and 5 K, 15 wt% sample showed uncompetitive lower critical current density , which ascribes the poor connectivity due to the excessive unsubstituted C distribution at grain boundaries and the presence of high MgO amount. At 24 and 28 K, the 4 and 6 wt% malic-acid-added samples exhibit a higher lateral force than pure sample. Based on the observed values of M- H, ( H) and lateral levitation force , it can be concluded that the 4 wt% malic-acid-added sample is the best of the studied samples.
,
2008-01-01
Each of the 50 States in the United States is beautiful in its own way. That beauty can be seen from a unique perspective using satellite images taken from high above the Earth. These State images were created from multiple satellite images stitched together into one seamless image for each State. Names of major cities, administrative boundaries, and State flags have been added.
Altered protein phosphorylation as a resource for potential AD biomarkers
Henriques, Ana Gabriela; Müller, Thorsten; Oliveira, Joana Machado; Cova, Marta; da Cruz e Silva, Cristóvão B.; da Cruz e Silva, Odete A. B.
2016-01-01
The amyloidogenic peptide, Aβ, provokes a series of events affecting distinct cellular pathways regulated by protein phosphorylation. Aβ inhibits protein phosphatases in a dose-dependent manner, thus it is expected that the phosphorylation state of specific proteins would be altered in response to Aβ. In fact several Alzheimer’s disease related proteins, such as APP and TAU, exhibit pathology associated hyperphosphorylated states. A systems biology approach was adopted and the phosphoproteome, of primary cortical neuronal cells exposed to Aβ, was evaluated. Phosphorylated proteins were recovered and those whose recovery increased or decreased, upon Aβ exposure across experimental sets, were identified. Significant differences were evident for 141 proteins and investigation of their interactors revealed key protein clusters responsive to Aβ treatment. Of these, 73 phosphorylated proteins increased and 68 decreased upon Aβ addition. These phosphorylated proteins represent an important resource of potential AD phospho biomarkers that should be further pursued. PMID:27466139
Was there a volcanic eruption off Vietnam in AD 608?
NASA Astrophysics Data System (ADS)
Khoo, T. T.
In the Sui-shu (Annals of the Sui Dynasty, 581-618), there is a record that returning envoys of the Chinese court to a state in northeastern Malay peninsula had in April-June AD 608 reached the state of Lin-i where for a whole day's sail the air around the vessel was yellowish and fetid. Lin-i was located at the southern end of the Annam Highlands chain and it is interpreted here that the phenominon reported could be due to a volcanic eruption in the Poulo Cecir-Ile des Cendres-Veteran volcanic islands group near the area. During the months of May to June the winds of the southwest monsoon, too, blow from the volcanic area toward the southern end of the Annam Highlands.
Altered protein phosphorylation as a resource for potential AD biomarkers.
Henriques, Ana Gabriela; Müller, Thorsten; Oliveira, Joana Machado; Cova, Marta; da Cruz E Silva, Cristóvão B; da Cruz E Silva, Odete A B
2016-07-28
The amyloidogenic peptide, Aβ, provokes a series of events affecting distinct cellular pathways regulated by protein phosphorylation. Aβ inhibits protein phosphatases in a dose-dependent manner, thus it is expected that the phosphorylation state of specific proteins would be altered in response to Aβ. In fact several Alzheimer's disease related proteins, such as APP and TAU, exhibit pathology associated hyperphosphorylated states. A systems biology approach was adopted and the phosphoproteome, of primary cortical neuronal cells exposed to Aβ, was evaluated. Phosphorylated proteins were recovered and those whose recovery increased or decreased, upon Aβ exposure across experimental sets, were identified. Significant differences were evident for 141 proteins and investigation of their interactors revealed key protein clusters responsive to Aβ treatment. Of these, 73 phosphorylated proteins increased and 68 decreased upon Aβ addition. These phosphorylated proteins represent an important resource of potential AD phospho biomarkers that should be further pursued.
Supporting Dynamic Ad hoc Collaboration Capabilities
Agarwal, Deborah A.; Berket, Karlo
2003-07-14
Modern HENP experiments such as CMS and Atlas involve as many as 2000 collaborators around the world. Collaborations this large will be unable to meet often enough to support working closely together. Many of the tools currently available for collaboration focus on heavy-weight applications such as videoconferencing tools. While these are important, there is a more basic need for tools that support connecting physicists to work together on an ad hoc or continuous basis. Tools that support the day-to-day connectivity and underlying needs of a group of collaborators are important for providing light-weight, non-intrusive, and flexible ways to work collaboratively. Some example tools include messaging, file-sharing, and shared plot viewers. An important component of the environment is a scalable underlying communication framework. In this paper we will describe our current progress on building a dynamic and ad hoc collaboration environment and our vision for its evolution into a HENP collaboration environment.
NASA Astrophysics Data System (ADS)
Chu, Chong-Sun; Giataganas, Dimitrios
2016-11-01
We propose and study a holographic dual of the type-IIB superstring theory of AdS5×S5 in terms of the N =4 superconformal Yang-Mills theory on dS4 . We develop the bulk to boundary formalism for the computation of the correlation functions to a wide class of theories. We apply it to compute the two-point correlators in the particular duality under study and we find that they agree with the expected results in d S conformal field theory. The gauge theory is expected to be UV finite and enjoy exact S L (2 ,Z ) strong-weak duality. As the string theory Green-Schwarz sigma model carries an infinite number of classically conserved charges, it also suggests that the superconformal Yang-Mills theory is integrable and deserves further studies.
Adding coal dust to coal batch
V.S. Shved; A.V.Berezin
2009-05-15
The granulometric composition of coke dust from the dry-slaking machine is determined. The influence of additions of 3-7% coke dust on the quality of industrial coking batch and the coke obtained by box coking is estimated. Adding 1% coke dust to coking batch does not markedly change the coke quality. Industrial equipment for the supply of dry-slaking dust to the batch is described.
ARM KAZR-ARSCL Value Added Product
Jensen, Michael
2012-09-28
The Ka-band ARM Zenith Radars (KAZRs) have replaced the long-serving Millimeter Cloud Radars, or MMCRs. Accordingly, the primary MMCR Value Added Product (VAP), the Active Remote Sensing of CLouds (ARSCL) product, is being replaced by a KAZR-based version, the KAZR-ARSCL VAP. KAZR-ARSCL provides cloud boundaries and best-estimate time-height fields of radar moments.
Appleby, C
1997-02-05
In the vast kit of tools used by corporate America to measure success, one has vaulted from the desks of CFOs to the cover of Fortune. Economic value added, better known as EVA, has become the tool of choice to assess shareholder value in publicly owned companies. Despite its Wall Street roots, advocates say EVA can also be applied to the traditionally not-for-profit health care industry, especially in an age of brutal competition for scarce capital.
Green, D.; von Segen, W.; Willits, S.
1995-09-01
Research results from the value-added research and demonstration program for western hardwoods are summarized in this report. The intent of the program was to enhance the economy of the Pacific Northwest by helping local communities and forest industries produce wood products more efficiently. Emphasis was given to value-added products and barriers to increased utilization. The program was coordinated by the Pacific Northwest Research Station, the Pacific Northwest region of State and Private Forestry, and the Forest Products Laboratory.
Latchoumane, Charles-Francois V; Kim, In-Hye; Sohn, Hansem; Jeong, Jaeseung
2013-01-01
This study applied dynamical nonstationarity analysis (DNA) to the resting EEGs of patients with attention-deficit/hyperactivity disorder (AD/HD). We aimed to assess and characterize AD/HD using features based on the local and global duration of dynamical microstate. We hypothesized that AD/HD patients would have difficulties in maintaining stable cognitive states (e.g., attention deficit and impulsivity) and that they would thus exhibit EEGs with temporal dynamics distinct from normal controls, i.e., rapidly and frequently changing dynamics. To test this hypothesis, we recorded EEGs from 12 adolescent subjects with AD/HD and 11 age-matched healthy subjects in the resting state with eyes closed and eyes open. We found that AD/HD patients exhibited significantly faster changes in dynamics than controls in the right temporal region during the eyes closed condition, but slower changes in dynamics in the frontal region during the eyes open condition. AD/HD patients exhibited a disruption in the rate of change of dynamics in the frontotemporal region at rest, probably due to executive and attention processes. We suggest that the DNA using complementary local and global features based on the duration of dynamical microstates could be a useful tool for the clinical diagnosis of subjects with AD/HD.
ADS: The Next Generation Search Platform
NASA Astrophysics Data System (ADS)
Accomazzi, A.; Kurtz, M. J.; Henneken, E. A.; Chyla, R.; Luker, J.; Grant, C. S.; Thompson, D. M.; Holachek, A.; Dave, R.; Murray, S. S.
2015-04-01
Four years after the last LISA meeting, the NASA Astrophysics Data System (ADS) finds itself in the middle of major changes to the infrastructure and contents of its database. In this paper we highlight a number of features of great importance to librarians and discuss the additional functionality that we are currently developing. Our citation coverage has doubled since 2010 and now consists of over 10 million citations. We are normalizing the affiliation information in our records and we have started collecting and linking funding sources with papers in our system. At the same time, we are undergoing major technology changes in the ADS platform. We have rolled out and are now enhancing a new high-performance search engine capable of performing full-text as well as metadata searches using an intuitive query language. We are currently able to index acknowledgments, affiliations, citations, and funding sources. While this effort is still ongoing, some of its benefits are already available through the ADS Labs user interface and API at http://adslabs.org/adsabs/.
Rotational-Mode-Shape-Based Added Mass Identification Using Wavelet Packet Transform
NASA Astrophysics Data System (ADS)
Rajendran, Prakash; Sivakumar, Srinivasan M.
2015-05-01
A novel approach is proposed in this article that the combination of rotational mode shape with wavelet packet transform can detect the relatively small added mass (damage) location and its intensity in a beam structure. The rotational mode shapes of added mass state are obtained from a finite element model and used as input in wavelet analysis to capture signatures arising from even small damage in the beam. The proposed algorithm is able to clearly identify single and multiple added mass locations and their intensities in a cantilever beam. It is also tested with noise-contaminated signals to show its feasibility in practical situations.
Bergman, Joseph; Brettholz, Izidor; Shneidman, Michael; Lerner, Vladimir
2003-01-01
Traditionally, the neuropsychiatric symptoms of Alzheimer's disease (AD) have been managed with neuroleptics or benzodiazepines, which have serious side effects. Preliminary observations suggest the possible value of cholinesterase inhibitors in the amelioration of psychotic symptoms in patients with dementia of the Alzheimer's type, dementia with Lewy bodies, and in patients with Parkinson's disease. Twelve inpatients with AD with psychotic symptoms and lack of improvement of their delusions/hallucinations during perphenazine treatment (8 mg/day) for 3 weeks received random open-label donepezil 5 mg daily in addition to an ongoing treatment of 8 mg/day perphenazine or 16 mg/day perphenazine. Assessments conducted at baseline and after weeks 2 and 4 included the Mini-Mental State Examination, the Global Deterioration Scale, the Positive and Negative Symptoms Scale, and the Clinical Global Impressions scale. Frequency of extrapyramidal symptoms was measured according to the Abnormal Involuntary Movement Scale. The donepezil-perphenazine group exhibited substantially greater and clinical improvements in mental state. At the end of the trial (4 weeks), Positive and Negative Symptoms Scale scores revealed significant differences between both groups (p = 0.006). The Clinical Global Impressions scale and the Mini-Mental State Examination scores also showed significant differences between the donepezil-perphenazine group and the perphenazine group (p = 0.028 and p = 0.027 respectively). No significant differences were found in the Global Deterioration Scale scores. Abnormal Involuntary Movement Scale scores showed a significant deterioration in extrapyramidal symptoms in the perphenazine group compared with the donepezil-perphenazine group (p = 0.016). Donepezil augmentation of neuroleptics may be appropriate for those patients for whom neuroleptic monotherapy either does not lead to symptom remission or is associated with intolerable adverse effects. This was an open
Added sugars drive nutrient and energy deficit in obesity: a new paradigm
DiNicolantonio, James J; Berger, Amy
2016-01-01
Obesity has traditionally been thought of as a state of caloric imbalance, where the intake of calories exceeds the expenditure or ‘burning’ of calories. However, a more nuanced appreciation for the complex biochemistry and physiology of cellular energy generation suggests that obesity is a state of hormonal imbalance causing increased shunting of food energy into adipose tissue for storage, resulting in decreased satiety and ultimately leading to increased caloric intake. Adding to this hypothesis, we propose that obesity is also a state of nutrient and energy deficit, leading to decreased fatty acid mobilisation and oxidation, the result of which may be a natural disinclination towards physical activity. Added sugars (sucrose, a.k.a. table sugar and high-fructose corn syrup) may provide energy (4 kcal/g) but at current intakes they do not facilitate—and may even hinder—the production of energy. Not only do added sugars displace nutritionally superior foods in the diet, but they may also deplete nutrients from other foods that have been consumed, as well as from body stores, in order to enable their proper oxidation and liberate their calories as energy. Additionally, the consumption of added sugars damages the mitochondria and hence impairs energy generation. Moreover, overconsuming added sugars may result in a kind of ‘internal starvation’ (via leptin and insulin resistance) leading to further hunger signals in the body. Added sugars promote nutrient and energy deficit and through this novel pathway promote obesity. PMID:27547437
Static strings in global AdS space and quark-antiquark potential
Bayona, C. A. Ballon; Ferreira, Cristine N.
2008-07-15
We investigate the finite temperature quark antiquark problem in a compact space S{sup n-1}xS{sup 1} by considering static strings in global AdS{sub n+1} space with n{>=}3. For high temperatures we work in the black hole metric where two possible solutions show up : the big black hole and the small black hole. Using the AdS/CFT correspondence, we calculate the quark antiquark potential (free energy) as a function of the distance. We show that this potential can be intrepeted as confining for the anti-de Sitter (AdS) space and deconfining for the big black hole. We find for the small black hole a confining limit for the potential but this solution is instable following the Hawking-Page criteria. Our results for the free energy reinforce the Witten interpretation of the confinement/deconfinement transition as the dual of the well-known Hawking-Page transition.
Vector condensate and AdS soliton instability induced by a magnetic field
NASA Astrophysics Data System (ADS)
Cai, Rong-Gen; Li, Li; Li, Li-Fang; Wu, You
2014-01-01
We continue to study the holographic p-wave superconductor model in the Einstein-Maxwell-complex vector field theory with a non-minimal coupling between the complex vector field and the Maxwell field. In this paper we work in the AdS soliton background which describes a conformal field theory in the confined phase and focus on the probe approximation. We find that an applied magnetic field can lead to the condensate of the vector field and the AdS soliton instability. As a result, a vortex lattice structure forms in the spatial directions perpendicular to the applied magnetic field. As a comparison, we also discuss the vector condensate in the Einstein-SU(2) Yang-Mills theory and find that in the setup of the present paper, the Einstein-Maxwell-complex vector field model is a generalization of the SU(2) model in the sense that the vector field has a general mass and gyromagnetic ratio.
Renormalization, averaging, conservation laws and AdS (in)stability
NASA Astrophysics Data System (ADS)
Craps, Ben; Evnin, Oleg; Vanhoof, Joris
2015-01-01
We continue our analytic investigations of non-linear spherically symmetric perturbations around the anti-de Sitter background in gravity-scalar field systems, and focus on conservation laws restricting the (perturbatively) slow drift of energy between the different normal modes due to non-linearities. We discover two conservation laws in addition to the energy conservation previously discussed in relation to AdS instability. A similar set of three conservation laws was previously noted for a self-interacting scalar field in a non-dynamical AdS background, and we highlight the similarities of this system to the fully dynamical case of gravitational instability. The nature of these conservation laws is best understood through an appeal to averaging methods which allow one to derive an effective Lagrangian or Hamiltonian description of the slow energy transfer between the normal modes. The conservation laws in question then follow from explicit symmetries of this averaged effective theory.
Massive quiver matrix models for massive charged particles in AdS
Asplund, Curtis T.; Denef, Frederik; Dzienkowski, Eric
2016-01-11
Here, we present a new class of N = 4 supersymmetric quiver matrix models and argue that it describes the stringy low-energy dynamics of internally wrapped D-branes in four-dimensional anti-de Sitter (AdS) flux compactifications. The Lagrangians of these models differ from previously studied quiver matrix models by the presence of mass terms, associated with the AdS gravitational potential, as well as additional terms dictated by supersymmetry. These give rise to dynamical phenomena typically associated with the presence of fluxes, such as fuzzy membranes, internal cyclotron motion and the appearance of confining strings. We also show how these models can be obtained by dimensional reduction of four-dimensional supersymmetric quiver gauge theories on a three-sphere.
Witten diagrams revisited: the AdS geometry of conformal blocks
Hijano, Eliot; Kraus, Per; Perlmutter, Eric; ...
2016-01-25
Here, we develop a new method for decomposing blocks. The steps involved are elementary, requiring no explicit integration, and operate directly in position space. Central to this construction is an appealingly simple answer to the question: what object in AdS computes a conformal block? The answer is a "geodesic Witten diagram", which is essentially an ordinary exchange Witten diagram, except that the cubic vertices are not integrated over all of AdS, but only over bulk geodesics connecting the boundary operators. In particular, we also consider the case of four-point functions of scalar operators, and show how to easily reproduce existingmore » results for the relevant conformal blocks in arbitrary dimension.« less
EXACT S-MATRICES FOR AdS3/CFT2
NASA Astrophysics Data System (ADS)
Ahn, Changrim; Bombardelli, Diego
2013-12-01
We propose exact S-matrices for the AdS3/CFT2 duality between type IIB strings on AdS3×S3×M4 with M4 = S3×S1 or T4 and the corresponding two-dimensional conformal field theories. We fix the two-particle S-matrices on the basis of the symmetries su(1|1) and su(1|1)×su(1|1). A crucial justification comes from the derivation of the all-loop Bethe ansatz matching exactly the recent conjecture proposed by Babichenko et al. [J. High Energy Phys.1003, 058 (2010), arXiv:0912.1723 [hep-th
Massive quiver matrix models for massive charged particles in AdS
Asplund, Curtis T.; Denef, Frederik; Dzienkowski, Eric
2016-01-11
Here, we present a new class of N = 4 supersymmetric quiver matrix models and argue that it describes the stringy low-energy dynamics of internally wrapped D-branes in four-dimensional anti-de Sitter (AdS) flux compactifications. The Lagrangians of these models differ from previously studied quiver matrix models by the presence of mass terms, associated with the AdS gravitational potential, as well as additional terms dictated by supersymmetry. These give rise to dynamical phenomena typically associated with the presence of fluxes, such as fuzzy membranes, internal cyclotron motion and the appearance of confining strings. We also show how these models can bemore » obtained by dimensional reduction of four-dimensional supersymmetric quiver gauge theories on a three-sphere.« less
Witten diagrams revisited: the AdS geometry of conformal blocks
Hijano, Eliot; Kraus, Per; Perlmutter, Eric; Snively, River
2016-01-25
Here, we develop a new method for decomposing blocks. The steps involved are elementary, requiring no explicit integration, and operate directly in position space. Central to this construction is an appealingly simple answer to the question: what object in AdS computes a conformal block? The answer is a "geodesic Witten diagram", which is essentially an ordinary exchange Witten diagram, except that the cubic vertices are not integrated over all of AdS, but only over bulk geodesics connecting the boundary operators. In particular, we also consider the case of four-point functions of scalar operators, and show how to easily reproduce existing results for the relevant conformal blocks in arbitrary dimension.
Supersymmetric AdS5 solutions of type IIB supergravity without D3 branes
NASA Astrophysics Data System (ADS)
Couzens, Christopher
2017-01-01
We analyse the most general bosonic supersymmetric solutions of type IIB supergravity whose metrics are warped products of five-dimensional anti-de Sitter space (AdS5) with a five-dimensional Riemannian manifold M 5, where the five-form flux vanishes, while all remaining fluxes are allowed to be non-vanishing consistent with SO(4,2) symmetry. This completes the program of classifying all supersymmetric solutions of ten and eleven-dimensional supergravity with an AdS5 factor. We investigate the supersymmetry conditions in some special cases, and demonstrate how these are satisfied by a solution originally found in [13], utilising the method of non-Abelian T-duality.
AdS black disk model for small-x DIS
NASA Astrophysics Data System (ADS)
Cornalba, Lorenzo; Costa, Miguel S.; Penedones, João
2011-05-01
Using the approximate conformal invariance of QCD at high energies we consider a simple AdS black disk model to describe saturation in DIS. Deep inside saturation the structure functions have the same power law scaling, FT˜FL˜x-ω, where ω is related to the expansion rate of the black disk with energy. Furthermore, the ratio FL/FT is given by the universal value 1+ω/3+ω, independently of the target.
Minisuperspace quantization of bubbling AdS2×S2 geometries
NASA Astrophysics Data System (ADS)
Li, Qinglin
2017-01-01
We quantize the moduli space of supersymmetric microstates describing four-dimensional black holes with AdS2×S2 asymptotics. To acquire the commutation relations of quantization, we find the symplectic form that is imposed in the Type IIB supergravity and defined in the space of solutions parametrized by one complex harmonic function in R3 with sources distributed along closed curves.
A comparative note on tunneling in AdS and in its boundary matrix dual
NASA Astrophysics Data System (ADS)
Chandrasekhar, B.; Mukherji, Sudipta; Sahay, Anurag; Sarkar, Swarnendu
2012-05-01
For charged black hole, within the grand canonical ensemble, the decay rate from thermal AdS to the black hole at a fixed high temperature increases with the chemical potential. We check that this feature is well captured by a phenomenological matrix model expected to describe its strongly coupled dual. This comparison is made by explicitly constructing the kink and bounce solutions around the de-confinement transition and evaluating the matrix model effective potential on the solutions.
Closed Timelike Curves in (2+1)-AdS Gravity
NASA Astrophysics Data System (ADS)
Valtancoli, P.
We build the (2+1)-AdS gravity generalization of the Gott time machine using a first-order formalism for solving the scattering of point sources. The two-body dynamics is solved by two invariant masses, whose difference is simply related to the total angular momentum of the system. We show how to build a time machine when at least one of the two invariant masses is no more real but acquires an imaginary part.
Time-dependent AdS backgrounds from S-branes
NASA Astrophysics Data System (ADS)
Deger, Nihat Sadik
2016-11-01
We construct time and radial dependent solutions that describe p-branes in chargeless S-brane backgrounds. In particular, there are some new M5- and D3-branes among our solutions which have AdS limits and contain a cosmological singularity as well. We also find a time-dependent version of the dyonic membrane configuration in 11-dimensions by applying a Lunin-Maldacena deformation to our new M5-brane solution.
Yangian of AdS3 / CFT2 and its deformation
NASA Astrophysics Data System (ADS)
Regelskis, Vidas
2016-08-01
We construct highest-weight modules and a Yangian extension of the centrally extended sl(1 | 1) 2 superalgebra, that is a symmetry of the worldsheet scattering associated with the AdS3 / CFT2 duality. We demonstrate that the R-matrix intertwining atypical modules has an elegant trigonometric parametrization. We also consider a quantum deformation of this superalgebra, its modules, and obtain a quantum affine extension of the Drinfeld-Jimbo type that describes a deformed worldsheet scattering.
A method to find N = 1 AdS4 vacua in type IIB
NASA Astrophysics Data System (ADS)
Solard, Gautier
2017-01-01
In this paper, we are looking for N = 1, AdS4 sourceless vacua in type IIB. While several examples exist in type IIA, there exists only one example of such vacua in type IIB. Thanks to the framework of generalized geometry we were able to devise a semi-algorithmical method to look for sourceless vacua. We present this method, which can easily be generalized to more complex cases, and give two new vacua in type IIB.
Mellin Amplitudes for Supergravity on AdS5×S5
NASA Astrophysics Data System (ADS)
Rastelli, Leonardo; Zhou, Xinan
2017-03-01
We revisit the calculation of holographic correlation functions in type-IIB supergravity on AdS5×S5 . Results for four-point functions simplify drastically when expressed in Mellin space. We conjecture a compact formula for the four-point functions of one-half Bogomol'nyi-Prasad-Sommerfield single-trace operators of arbitrary weight. Our methods rely on general consistency conditions and eschew detailed knowledge of the supergravity effective action.
On elliptic string solutions in AdS3 and dS3
NASA Astrophysics Data System (ADS)
Bakas, Ioannis; Pastras, Georgios
2016-07-01
Classical string actions in AdS3 and dS3 can be connected to the sinh-Gordon and cosh-Gordon equations through Pohlmeyer reduction. We show that the problem of constructing a classical string solution with a given static or translationally invariant Pohlmeyer counterpart is equivalent to solving four pairs of effective Schrödinger problems. Each pair consists of a flat potential and an n = 1 Lamé potential whose eigenvalues are connected, and, additionally, the four solutions satisfy a set of constraints. An approach for solving this system is developed by employing an interesting connection between the specific class of classical string solutions and the band structure of the Lamé potential. This method is used for the construction of several families of classical string solutions, one of which turns out to be the spiky strings in AdS3. New solutions include circular rotating strings in AdS3 with singular time evolution of their radius and angular velocity as well as classical string solutions in dS3.
Holographic estimation of multiplicity and the collision of membranes in modified AdS5 spaces
NASA Astrophysics Data System (ADS)
Aref'eva, I. Ya.; Pozdeeva, E. O.; Pozdeeva, T. O.
2013-07-01
The quark-gluon plasma formed as a result of heavy-ion collisions is currently investigated actively both theoretically and experimentally. According to the holographic approach, forming a quark-gluon plasma in the four-dimensional world is associated with creating black holes in a five-dimensional anti-de Sitter (AdS) space. The multiplicity of particles produced in heavy-ion collisions is then determined by the entropy of the five-dimensional black hole, which is estimated by the area of the trapped surface. In this approach, we can model the dependence of the entropy on the energy of the colliding ions and thus the dependence of the multiplicity on the energy, and we can also compare the theoretical results with experimental data. To obtain a variety of model dependences on the energy, we consider the formation of black holes in modified AdS spaces, namely, in AdS spaces with different b factors. We find dynamics of the change of the trapped surface area depending on the energy for each investigated space.
Korean nova records in A.D. 1073 and A.D. 1074: R Aquarii
NASA Astrophysics Data System (ADS)
Yang, Hong-Jin; Park, Myeong-Gu; Cho, Se-Hyung; Park, Changbom
2005-05-01
R Aqr is known to be a symbiotic binary system with an associated extended emission nebula, possibly produced by a historic outburst. To find the associated historic records, we searched for and compiled all Guest Star and Peculiar Star records in three Korean official history books that cover almost two thousand years, Samguksagi, Goryeosa, Joseonwangjosillok. In addition to the record of A.D. 1073, previously noted by Li (1985, Chin. Astron. Astrophys., 9, 322), we have found in Goryeosa another candidate record of A.D. 1074, which has the same positional description as that of A.D. 1073 with an additional brightness description. We examined various aspects of the two records and conclude that they both are likely to be the records of outburst of R Aqr. This means that there were two successive outbursts in A.D. 1073 and in A.D. 1074, separated by approximately one year. Based on these records, we estimate the distance to R Aqr to be 273 pc if the expansion of the nebula has been at a constant rate. The brightness record of A.D. 1074 corresponds to the absolute magnitude at outburst of Moutburst = -6.2m -5.2m at this distance. The two Korean records associated with R Aqr may provide astronomically meaningful constraints to the outburst model of R Aqr and the formative process of its nebulosity.
AdS black holes, the bulk-boundary dictionary, and smearing functions
NASA Astrophysics Data System (ADS)
Leichenauer, Stefan; Rosenhaus, Vladimir
2013-07-01
In Lorentzian AdS/CFT there exists a mapping between local bulk operators and nonlocal conformal field theory (CFT) operators. In global anti-de Sitter (AdS) this mapping can be found through use of bulk equations of motion and allows the nonlocal CFT operator to be expressed as a local operator smeared over a range of positions and times. We argue that such a construction is not possible if there are bulk normal modes with exponentially small near boundary imprint. We show that the AdS-Schwarzschild background is such a case, with the horizon introducing modes with angular momentum much larger than frequency, causing them to be trapped by the centrifugal barrier. More generally, we argue that any barrier in the radial effective potential which prevents null geodesics from reaching the boundary will lead to modes with vanishingly small near boundary imprint, thereby obstructing the existence of a smearing function. While one may have thought the bulk-boundary dictionary for low curvature regions, such as the exterior of a black hole, should be as in empty AdS, our results demonstrate otherwise.
Entropy of near-extremal black holes in AdS5
Simon, Joan; Balasubramanian, Vijay; de Boer, Jan; Jejjala, Vishnu; Simon, Joan
2007-07-24
We construct the microstates of near-extremal black holes in AdS_5 x S5 as gases of defects distributed in heavy BPS operators in the dual SU(N) Yang-Mills theory. These defects describe open strings on spherical D3-branes in the S5, and we show that they dominate the entropy by directly enumerating them and comparing the results with a partition sum calculation. We display new decoupling limits in which the field theory of the lightest open strings on the D-branes becomes dual to a near-horizon region of the black hole geometry. In the single-charge black hole we find evidence for an infrared duality between SU(N) Yang-Mills theories that exchanges the rank of the gauge group with an R-charge. In the two-charge case (where pairs of branes intersect on a line), the decoupled geometry includes an AdS_3 factor with a two-dimensional CFT dual. The degeneracy in this CFT accounts for the black hole entropy. In the three-charge case (where triples of branes intersect at a point), the decoupled geometry contains an AdS_2 factor. Below a certain critical mass, the two-charge system displays solutions with naked timelike singularities even though they do not violate a BPS bound. We suggest a string theoretic resolution of these singularities.
Supersymmetry of IIA warped flux AdS and flat backgrounds
NASA Astrophysics Data System (ADS)
Beck, S.; Gutowski, J.; Papadopoulos, G.
2015-09-01
We identify the fractions of supersymmetry preserved by the most general warped flux AdS and flat backgrounds in both massive and standard IIA supergravities. We find that AdS n × w M 10 - n preserve {2}^{[n/2]}k for n ≤ 4 and {2}^{[n/2]+1}k for 4 < n ≤ 7 supersymmetries, k ∈ ℕ >0. In addition we show that, for suitably restricted fields and M 10 - n , the killing spinors of AdS backgrounds are given in terms of the zero modes of Dirac like operators on M 10 - n . This generalizes the Lichnerowicz theorem for connections whose holonomy is included in a general linear group. We also adapt our results to ℝ 1, n - 1 × w M 10 - n backgrounds which underpin flux compactifications to ℝ 1, n - 1 and show that these preserve {2}^{[n/2]}k for 2
Non-split and split deformations of {{AdS}}_{5}
NASA Astrophysics Data System (ADS)
Hoare, Ben; van Tongeren, Stijn J.
2016-12-01
The η deformation of the {{AdS}}5× {S}5 superstring depends on a non-split r matrix for the superalgebra {psu}(2,2| 4). Much of the investigation into this model has considered one particular choice, however there are a number of inequivalent alternatives. This is also true for the bosonic sector of the theory with {su}(2,2), the isometry algebra of {{AdS}}5, admitting one split and three non-split r matrices. In this article we explore these r matrices and the corresponding geometries. We investigate their contraction limits, comment on supergravity backgrounds and demonstrate their relation to gauged-WZW deformations. We then extend the three non-split cases to {{AdS}}5× {S}5 and compute four separate bosonic two-particle tree-level S-matrices based on inequivalent BMN-type light-cone gauges. The resulting S-matrices, while different, are related by momentum-dependent one-particle changes of basis.
AD-1 multiple exposure showing wing sweep
NASA Technical Reports Server (NTRS)
1980-01-01
This photograph is a multiple exposure showing the AD-1 aircraft with its wing swept at different angles between zero and 60 degrees. The Ames-Dryden-1 (AD-1) aircraft was designed to investigate the concept of an oblique (pivoting) wing. The wing could be rotated on its center pivot, so that it could be set at its most efficient angle for the speed at which the aircraft was flying. NASA Ames Research Center Aeronautical Engineer Robert T. Jones conceived the idea of an oblique wing. His wind tunnel studies at Ames (Moffett Field, CA) indicated that an oblique wing design on a supersonic transport might achieve twice the fuel economy of an aircraft with conventional wings. The oblique wing on the AD-1 pivoted about the fuselage, remaining perpendicular to it during slow flight and rotating to angles of up to 60 degrees as aircraft speed increased. Analytical and wind tunnel studiesthat Jones conducted at Ames indicated that a transport-sized oblique-wing aircraft flying at speeds of up to Mach 1.4 (1.4 times the speed of sound) would have substantially better aerodynamic performance than aircraft with conventional wings. The AD-1 structure allowed the project to complete all of its technical objectives. The type of low-speed, low-cost vehicle - as expected - exhibited aeroelastic and pitch-roll-coupling effects that contributed to poor handling at sweep angles above 45 degrees. The fiberglass structure limited the wing stiffness that would have improved the handling qualities. Thus, after completion of the AD-1 project, there was still a need for a transonic oblique-wing research aircraft to assess the effects of compressibility, evaluate a more representative structure, and analyze flight performance at transonic speeds (those on either side of the speed of sound). The aircraft was delivered to the Dryden Flight Research Center, Edwards, CA, in March 1979 and its first flight was on December 21, 1979. Piloting the aircraft on that flight, as well as on its last
Vaz, Cenalo; Tibrewala, Rakesh; Singh, T. P.
2008-07-15
In a previous paper we studied the collapse of a spherically symmetric dust distribution (marginally bound Lemaitre-Tolman-Bondi) in d-dimensional anti-de Sitter spacetime and obtained the condition for the formation of trapped surfaces. Here we extend the analysis by giving the canonical theory for the same and subsequently quantize the system by solving the Wheeler-DeWitt equation. We show that for the case of small dust perturbations around a black hole the wave functionals so obtained describe a flux of dust particles from the region near the horizon with a thermal spectrum at the Hawking temperature and discuss the nontrivial dependence of this temperature on the number of spacetime dimensions and the cosmological constant.
NASA Astrophysics Data System (ADS)
Gubser, Steven S.; Knaute, Johannes; Parikh, Sarthak; Samberg, Andreas; Witaszczyk, Przemek
2017-01-01
We construct a p-adic analog to AdS/CFT, where an unramified extension of the p-adic numbers replaces Euclidean space as the boundary and a version of the Bruhat-Tits tree replaces the bulk. Correlation functions are computed in the simple case of a single massive scalar in the bulk, with results that are strikingly similar to ordinary holographic correlation functions when expressed in terms of local zeta functions. We give some brief discussion of the geometry of p-adic chordal distance and of Wilson loops. Our presentation includes an introduction to p-adic numbers.
Gauged Ads-Maxwell Algebra and Gravity
NASA Astrophysics Data System (ADS)
Durka, R.; Kowalski-Glikman, J.; Szczachor, M.
We deform the anti-de Sitter algebra by adding additional generators {Z}ab, forming in this way the negative cosmological constant counterpart of the Maxwell algebra. We gauge this algebra and construct a dynamical model with the help of a constrained BF theory. It turns out that the resulting theory is described by the Einstein-Cartan action with Holst term, and the gauge fields associated with the Maxwell generators {Z}ab appear only in topological terms that do not influence dynamical field equations. We briefly comment on the extension of this construction, which would lead to a nontrivial Maxwell fields dynamics.
The NASA ADS: Searching, Linking and More
NASA Technical Reports Server (NTRS)
Thompson, D. M.; Eichhorn, G.; Accomazzi, A.; Bohlen, E.; Grant, C. S.; Henneken, E.; Kurtz, M.; Murray, S.
2004-01-01
The NASA ADS Abstract Service is a NASA-funded project which provides FREE World Wide Web abstract search services. We currently have over 3.6 million references in four databases: 1) Astronomy and Planetary Sciences; 2) Physics and Geophysics; 3) Space Instrumentation; and 4) Astronomy Preprints. Our eleven mirror sites in France, Germany, Japan, Chile, Great Britain, India, Russia, Brazil, Argentina, Korea and China help to provide better global access. Each database contains abstracts from hundreds of journals, publications, colloquia, symposia, proceedings, PhD Theses, and NASA reports. All abstracts can be searched by author, title, or abstract text words.
Cognitive Impact of Banner Ad Characteristics: An Experimental Study.
ERIC Educational Resources Information Center
Li, Hairong; Bukovac, Janice L.
1999-01-01
Finds that (1) animated banner ads (display advertisements hyperlinked to an advertiser's Web site) result in quicker response and better recall (from college students) than non-animated banner ads; (2) larger banner ads lead to better comprehension and more clicks than small banner ads; and (3) user mode (information seeking or Web surfing) did…
37 CFR 2.98 - Adding party to interference.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Adding party to interference....98 Adding party to interference. A party may be added to an interference only upon petition to the... interference is not added, the examiner may suspend action on the application pending termination of...
37 CFR 2.98 - Adding party to interference.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Adding party to interference....98 Adding party to interference. A party may be added to an interference only upon petition to the... interference is not added, the examiner may suspend action on the application pending termination of...
21 CFR 509.6 - Added poisonous or deleterious substances.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Added poisonous or deleterious substances. 509.6...-PACKAGING MATERIAL General Provisions § 509.6 Added poisonous or deleterious substances. (a) Use of an added... approved under the criteria of section 409 of the act, or when the added poisonous or deleterious...
7 CFR 58.727 - Adding optional ingredients.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 3 2011-01-01 2011-01-01 false Adding optional ingredients. 58.727 Section 58.727... Procedures § 58.727 Adding optional ingredients. As each batch is added to the cooker, the predetermined amounts of salt, emulsifiers, color, or other allowable optional ingredients shall be added. However,...
37 CFR 2.98 - Adding party to interference.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Adding party to interference....98 Adding party to interference. A party may be added to an interference only upon petition to the... interference is not added, the examiner may suspend action on the application pending termination of...
21 CFR 509.6 - Added poisonous or deleterious substances.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 6 2012-04-01 2012-04-01 false Added poisonous or deleterious substances. 509.6...-PACKAGING MATERIAL General Provisions § 509.6 Added poisonous or deleterious substances. (a) Use of an added... approved under the criteria of section 409 of the act, or when the added poisonous or deleterious...
7 CFR 58.727 - Adding optional ingredients.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 7 Agriculture 3 2014-01-01 2014-01-01 false Adding optional ingredients. 58.727 Section 58.727... Procedures § 58.727 Adding optional ingredients. As each batch is added to the cooker, the predetermined amounts of salt, emulsifiers, color, or other allowable optional ingredients shall be added. However,...
21 CFR 509.6 - Added poisonous or deleterious substances.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Added poisonous or deleterious substances. 509.6...-PACKAGING MATERIAL General Provisions § 509.6 Added poisonous or deleterious substances. (a) Use of an added... approved under the criteria of section 409 of the act, or when the added poisonous or deleterious...
37 CFR 2.98 - Adding party to interference.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Adding party to interference....98 Adding party to interference. A party may be added to an interference only upon petition to the... interference is not added, the examiner may suspend action on the application pending termination of...
7 CFR 58.727 - Adding optional ingredients.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 3 2013-01-01 2013-01-01 false Adding optional ingredients. 58.727 Section 58.727... Procedures § 58.727 Adding optional ingredients. As each batch is added to the cooker, the predetermined amounts of salt, emulsifiers, color, or other allowable optional ingredients shall be added. However,...
37 CFR 2.98 - Adding party to interference.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Adding party to interference....98 Adding party to interference. A party may be added to an interference only upon petition to the... interference is not added, the examiner may suspend action on the application pending termination of...
21 CFR 509.6 - Added poisonous or deleterious substances.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Added poisonous or deleterious substances. 509.6...-PACKAGING MATERIAL General Provisions § 509.6 Added poisonous or deleterious substances. (a) Use of an added... approved under the criteria of section 409 of the act, or when the added poisonous or deleterious...
21 CFR 109.6 - Added poisonous or deleterious substances.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Added poisonous or deleterious substances. 109.6...-PACKAGING MATERIAL General Provisions § 109.6 Added poisonous or deleterious substances. (a) Use of an added... approved under the criteria of section 409 of the act, or when the added poisonous or deleterious...
7 CFR 58.727 - Adding optional ingredients.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 3 2012-01-01 2012-01-01 false Adding optional ingredients. 58.727 Section 58.727... Procedures § 58.727 Adding optional ingredients. As each batch is added to the cooker, the predetermined amounts of salt, emulsifiers, color, or other allowable optional ingredients shall be added. However,...
21 CFR 109.6 - Added poisonous or deleterious substances.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Added poisonous or deleterious substances. 109.6...-PACKAGING MATERIAL General Provisions § 109.6 Added poisonous or deleterious substances. (a) Use of an added... approved under the criteria of section 409 of the act, or when the added poisonous or deleterious...
21 CFR 109.6 - Added poisonous or deleterious substances.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Added poisonous or deleterious substances. 109.6...-PACKAGING MATERIAL General Provisions § 109.6 Added poisonous or deleterious substances. (a) Use of an added... approved under the criteria of section 409 of the act, or when the added poisonous or deleterious...
21 CFR 509.6 - Added poisonous or deleterious substances.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 6 2014-04-01 2014-04-01 false Added poisonous or deleterious substances. 509.6...-PACKAGING MATERIAL General Provisions § 509.6 Added poisonous or deleterious substances. (a) Use of an added... approved under the criteria of section 409 of the act, or when the added poisonous or deleterious...
21 CFR 109.6 - Added poisonous or deleterious substances.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Added poisonous or deleterious substances. 109.6...-PACKAGING MATERIAL General Provisions § 109.6 Added poisonous or deleterious substances. (a) Use of an added... approved under the criteria of section 409 of the act, or when the added poisonous or deleterious...
76 FR 71430 - Automatic Dependent Surveillance Broadcast (ADS-B)
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... a global strategy to proceed with ADS-B In while ensuring compatibility with the standards adopted... the ADS-B In Aviation Rulemaking Committee, Recommendations to Define a Strategy for Incorporating ADS... forum for the U.S. and international aviation community to define a strategy for incorporating ADS-B...
ERIC Educational Resources Information Center
Goldhaber, Dan
2015-01-01
The past decade has seen a tremendous amount of research on the use of value-added modeling to assess individual teachers, and a significant number of states and districts are now using, or plan to use, value added as a component of a teacher's summative performance evaluation. In this article, I explore the various mechanisms through which the…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-17
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Will Courts Shape Value-Added Methods for Teacher Evaluation? ACT Working Paper Series. WP-2014-2
ERIC Educational Resources Information Center
Croft, Michelle; Buddin, Richard
2014-01-01
As more states begin to adopt teacher evaluation systems based on value-added measures, legal challenges have been filed both seeking to limit the use of value-added measures ("Cook v. Stewart") and others seeking to require more robust evaluation systems ("Vergara v. California"). This study reviews existing teacher evaluation…
Television Ads in Singapore: A Content Analysis.
ERIC Educational Resources Information Center
Rehman, Sharaf N.; Aw, Annette; Kennan, William
1999-01-01
Appraises the information content of Singapore television advertising, and makes a comparison with relevant United States findings. Research reported in this paper is a replication of two empirical studies of the informational content of television advertising in the United States from 1977. (Author/LRW)
Districts Gird for Added Use of Nonfiction
ERIC Educational Resources Information Center
Gewertz, Catherine
2012-01-01
An intensifying focus for teachers across the country is how to develop students' skills at reading and understanding informational texts. Teachers are rebalancing their fiction-and-nonfiction scales because the Common Core State Standards in English/language arts demand it. Since all but four states have adopted those guidelines, millions of…
Evasion of added isotopic mercury from a northern temperate lake
Southworth, G.; Lindberg, S.; Hintelmann, H.; Amyot, M.; Poulain, A.; Bogle, M.; Peterson, M.; Rudd, J.; Harris, R.; Sandilands, K.; Krabbenhoft, D.; Olsen, M.
2007-01-01
Isotopically enriched Hg (90% 202Hg) was added to a small lake in Ontario, Canada, at a rate equivalent to approximately threefold the annual direct atmospheric deposition rate that is typical of the northeastern United States. The Hg spike was thoroughly mixed into the epilimnion in nine separate events at two-week intervals throughout the summer growing season for three consecutive years. We measured concentrations of spike and ambient dissolved gaseous Hg (DGM) concentrations in surface water and the rate of volatilization of Hg from the lake on four separate, week-long sampling periods using floating dynamic flux chambers. The relationship between empirically measured rates of spike-Hg evasion were evaluated as functions of DGM concentration, wind velocity, and solar illumination. No individual environmental variable proved to be a strong predictor of the evasion flux. The DGM-normalized flux (expressed as the mass transfer coefficient, k) varied with wind velocity in a manner consistent with existing models of evasion of volatile solutes from natural waters but was higher than model estimates at low wind velocity. The empirical data were used to construct a description of evasion flux as a function of total dissolved Hg, wind, and solar illumination. That model was then applied to data for three summers for the experiment to generate estimates of Hg re-emission from the lake surface to the atmosphere. Based on ratios of spike Hg to ambient Hg in DGM and dissolved total Hg pools, ratios of DGM to total Hg in spike and ambient Hg pools, and flux estimates of spike and ambient Hg, we concluded that the added Hg spike was chemically indistinguishable from the ambient Hg in its behavior. Approximately 45% of Hg added to the lake over the summer was lost via volatilization. ?? 2007 SETAC.
Evasion of added isotopic mercury from a northern temperate lake.
Southworth, George; Lindberg, Steven; Hintelmann, Holger; Amyot, Marc; Poulain, Alexandre; Bogle, Maryanna; Peterson, Mark; Rudd, John; Harris, R; Sandilands, Kenneth; Krabbenhoft, David; Olsen, Mark
2007-01-01
Isotopically enriched Hg (90% 202Hg) was added to a small lake in Ontario, Canada, at a rate equivalent to approximately threefold the annual direct atmospheric deposition rate that is typical of the northeastern United States. The Hg spike was thoroughly mixed into the epilimnion in nine separate events at two-week intervals throughout the summer growing season for three consecutive years. We measured concentrations of spike and ambient dissolved gaseous Hg (DGM) concentrations in surface water and the rate of volatilization of Hg from the lake on four separate, week-long sampling periods using floating dynamic flux chambers. The relationship between empirically measured rates of spike-Hg evasion were evaluated as functions of DGM concentration, wind velocity, and solar illumination. No individual environmental variable proved to be a strong predictor of the evasion flux. The DGM-normalized flux (expressed as the mass transfer coefficient, k) varied with wind velocity in a manner consistent with existing models of evasion of volatile solutes from natural waters but was higher than model estimates at low wind velocity. The empirical data were used to construct a description of evasion flux as a function of total dissolved Hg, wind, and solar illumination. That model was then applied to data for three summers for the experiment to generate estimates of Hg re-emission from the lake surface to the atmosphere. Based on ratios of spike Hg to ambient Hg in DGM and dissolved total Hg pools, ratios of DGM to total Hg in spike and ambient Hg pools, and flux estimates of spike and ambient Hg, we concluded that the added Hg spike was chemically indistinguishable from the ambient Hg in its behavior. Approximately 45% of Hg added to the lake over the summer was lost via volatilization.
AD performance and its extension towards ELENA
NASA Astrophysics Data System (ADS)
Oelert, Walter; Eriksson, Tommy; Belochitskii, Pavel; Tranquille, Gerard
2012-12-01
The CERN's Antiproton Decelerator (AD) is devoted to special experiments with low energy antiprotons. A main topic is the antihydrogen production with the present aim to produce these antimatter atoms with such low energy that they can be trapped in a magnetic gradient field. First very convincing results have been published recently by ALPHA. Still, it appears to be cumbersome, time consuming and ineffective when collecting the needed large numbers and high densities of antiproton clouds with the present AD. Both the effectiveness and the availability for additional experiments at this unique facility would drastically increase, if the antiproton beam of presently 5 MeV kinetic energy would be reduced by an additional decelerator to something like 100 keV. Such a facility "ELENA", as an abbreviation for Extra Low ENergy Antiproton Ring and first discussed in 1982 for LEAR, was freshly proposed with a substantial new design and revised layout and is presently under consideration. ELENA will increase the number of useful antiprotons by up to two orders of magnitude and will allow to serve up to four experiments in parallel.
AD performance and its extension towards ELENA
NASA Astrophysics Data System (ADS)
Oelert, Walter; Eriksson, Tommy; Belochitskii, Pavel; Tranquille, Gerard
The CERN's Antiproton Decelerator (AD) is devoted to special experiments with low energy antiprotons. A main topic is the antihydrogen production with the present aim to produce these antimatter atoms with such low energy that they can be trapped in a magnetic gradient field. First very convincing results have been published recently by ALPHA. Still, it appears to be cumbersome, time consuming and ineffective when collecting the needed large numbers and high densities of antiproton clouds with the present AD. Both the effectiveness and the availability for additional experiments at this unique facility would drastically increase, if the antiproton beam of presently 5 MeV kinetic energy would be reduced by an additional decelerator to something like 100 keV. Such a facility "ELENA", as an abbreviation for Extra Low ENergy Antiproton Ring and first discussed in 1982 for LEAR, was freshly proposed with a substantial new design and revised layout and is presently under consideration. ELENA will increase the number of useful antiprotons by up to two orders of magnitude and will allow to serve up to four experiments in parallel.
Enabling Meaningful Affiliation Searches in the ADS
NASA Astrophysics Data System (ADS)
Grant, C. S.; Thompson, D. M.; Chyla, R.; Holachek, A.; Accomazzi, A.; Henneken, E. A.; Kurtz, M. J.; Luker, J.; Murray, S. S.
2015-04-01
For many years, users have wanted to search affiliations in the ADS in order to build institutional databases and to help with author disambiguation. Although we currently provide this capability upon request, we have yet to incorporate it as part of the operational Abstract Service. This is because it cannot be used reliably, primarily because of the lack of uniform representation of the affiliation data. In an effort to make affiliation searches more meaningful, we have designed a two-tiered hierarchy of standard institutional names based on Ringgold identifiers, with the expectation that this will enable us to implement a search by institution, which will work for the vast majority of institutions. It is our intention to provide the capability of searching the ADS both by standard affiliation name and original affiliation string, as well as to enable autosuggest of affiliations as a means of helping to disambiguate author identification. Some institutions are likely to require manual work, and we encourage interested librarians to assist us in standardizing the representation of their institutions in the affiliation field.
Frozen yogurt with added inulin and isomalt.
Isik, U; Boyacioglu, D; Capanoglu, E; Erdil, D Nilufer
2011-04-01
The objective of this study was to produce a frozen yogurt containing low fat and no added sugar. Samples containing 5% polydextrose, 0.065% aspartame and acesulfame-K mixture, and different levels of inulin and isomalt (5.0, 6.5, and 8.0%) were produced at pilot scale and analyzed for their physical and chemical properties including proximate composition, viscosity, acidity, overrun, melting rate, heat shock stability, as well as sensory characteristics, and viability of lactic acid bacteria. With the addition of inulin and isomalt, viscosity increased by 19 to 52% compared with that of sample B (reduced-fat control). The average calorie values of samples substituted with sweeteners were about 43% lower than that of original sample. Low-calorie frozen yogurt samples melted about 33 to 48% slower than the reduced-fat control sample at 45 min. Based on quantitative descriptive profile test results, statistically significant differences among products were observed for hardness, iciness, foamy melting, whey separation, and sweetness characteristics. The results of principal component analysis showed that the sensory properties of the sample containing 6.5% inulin and 6.5% isomalt were similar to those of control. Lactic acid bacteria counts of frozen yogurt were found to be between 8.12 and 8.49 log values, 3 mo after the production. The overall results showed that it is possible to produce an attractive frozen yogurt product with the incorporation of inulin and isomalt with no added sugar and reduced fat.
Variations of 14C around AD 775 and AD 1795 - due to solar activity
NASA Astrophysics Data System (ADS)
Neuhäuser, R.; Neuhäuser, D. L.
2015-12-01
The motivation for our study is the disputed cause for the strong variation of 14C around AD 775. Our method is to compare the 14C variation around AD 775 with other periods of strong variability. Our results are: (a) We see three periods, where 14C varied over 200 yr in a special way showing a certain pattern of strong secular variation: after a Grand Minimum with strongly increasing 14C, there is a series of strong short-term drop(s), rise(s), and again drop(s) within 60 yr, ending up to 200 yr after the start of the Grand Minimum. These three periods include the strong rises around BC 671, AD 775, and AD 1795. (b) We show with several solar activity proxies (radioisotopes, sunspots, and aurorae) for the AD 770s and 1790s that such intense rapid 14C increases can be explained by strong rapid decreases in solar activity and, hence, wind, so that the decrease in solar modulation potential leads to an increase in radioisotope production. (c) The strong rises around AD 775 and 1795 are due to three effects, (i) very strong activity in the previous cycles (i.e. very low 14C level), (ii) the declining phase of a very strong Schwabe cycle, and (iii) a phase of very weak activity after the strong 14C rise - very short and/or weak cycle(s) like the suddenly starting Dalton minimum. (d) Furthermore, we can show that the strong change at AD 1795 happened after a pair of two packages of four Schwabe cycles with certain hemispheric leadership (each package consists of two Gnevyshev-Ohl pairs, respectively two Hale-Babcock pairs). We show with several additional arguments that the rise around AD 775 was not that special. We conclude that such large, short-term rises in 14C (around BC 671, AD 775, and 1795) do not need to be explained by highly unlikely solar super-flares nor other rare events, but by extra-solar cosmic rays modulated due to solar activity variations.
The Black Hole Firewall and Top-Down Constructions of AdS/CFT
NASA Astrophysics Data System (ADS)
Almheiri, Ahmed Eid Khamis Thani
In the first part of this dissertation we argue that the following statements cannot be all true: (i) Black hole formation and evaporation is a unitary process as viewed by external observers, (ii) Physics outside some microscopic distance away from the event horizon is described by local effective quantum field theory, (iii) A black hole is a quantum system with a finite number of states given by the exponential of the Bekenstein Hawking entropy, and (iv) An infalling observer's experience in the vicinity of the horizon is well described by local effective quantum field theory in the infalling reference frame. We argue that the most conservative resolution is that an infalling observer will see drastic violations of effective field theory far away from the singularity, and encounter high energy quanta, a firewall, just behind the black hole event horizon. We address counter proposals to the firewall which involve, in one way or another, radical modifications of quantum mechanics or locality, and argue that they are unsatisfactory in their current formulation. We conclude this part with an investigation into the existence of firewalls in the two dimensional Einstein-dilaton gravity model of CGHS. We find that black holes in such models do not develop firewalls, but rather evaporate down to form small mass remnants. We elaborate on why this is inevitable in two dimensions and argue against a similar conclusion in higher dimensions. In the second part of this dissertation we construct AdS2 and AdS3 magnetic brane solutions within the abelian truncations of AdS4 x orbifolded S7 and AdS5 x S5 supergravity. We find a class of supersymmetric solutions of the bulk theory to assure stability. We perform a preliminary analysis demonstrating the stability of some nonsupersymmetric embeddings. We identify the dual field theory and compare the thermal entropies across the duality. We end with an investigatation into the effects of backreaction on holography in AdS2. We study a
Adding kinetics and hydrodynamics to the CHEETAH thermochemical code
Fried, L.E., Howard, W.M., Souers, P.C.
1997-01-15
In FY96 we released CHEETAH 1.40, which made extensive improvements on the stability and user friendliness of the code. CHEETAH now has over 175 users in government, academia, and industry. Efforts have also been focused on adding new advanced features to CHEETAH 2.0, which is scheduled for release in FY97. We have added a new chemical kinetics capability to CHEETAH. In the past, CHEETAH assumed complete thermodynamic equilibrium and independence of time. The addition of a chemical kinetic framework will allow for modeling of time-dependent phenomena, such as partial combustion and detonation in composite explosives with large reaction zones. We have implemented a Wood-Kirkwood detonation framework in CHEETAH, which allows for the treatment of nonideal detonations and explosive failure. A second major effort in the project this year has been linking CHEETAH to hydrodynamic codes to yield an improved HE product equation of state. We have linked CHEETAH to 1- and 2-D hydrodynamic codes, and have compared the code to experimental data. 15 refs., 13 figs., 1 tab.
Brain sterol dys-regulation in sporadic AD and MCI: Relationship to heme oxygenase-1
Hascalovici, Jacob R.; Vaya, Jacob; Khatib, Soliman; Holcroft, Christina A.; Zukor, Hillel; Song, Wei; Arvanitakis, Zoe; Bennett, David A.; Schipper, Hyman M.
2009-01-01
The objective of this study was to ascertain the impact of aging and Alzheimer disease (AD) on brain cholesterol (CH), CH precursors and oxysterol homeostasis. Altered CH metabolism and up-regulation of heme oxygenase-1 (HO-1) are characteristic of AD-affected neural tissues. We recently determined that HO-1 over-expression suppresses total CH levels by augmenting liver X receptor-mediated CH efflux and enhances oxysterol formation in cultured astroglia. Lipids and proteins were extracted from post-mortem human frontal cortex derived from subjects with sporadic AD, mild cognitive impairment (MCI) and no cognitive impairment (NCI; n=17 per group) enrolled in the Religious Orders Study, an ongoing clinical-pathologic study of aging and AD. ELISA was used to quantify human HO-1 protein expression from brain tissue and GC-MS to quantify total CH, CH precursors and relevant oxysterols. The relationships of sterol/oxysterol levels to HO-1 protein expression and clinical/demographic variables were determined by multivariable regression and non-parametric statistical analyses. Decreased CH, increased oxysterol and increased CH precursors concentrations in the cortex correlated significantly with HO-1 levels in MCI and AD, but not NCI. Specific oxysterols correlated with disease state, increasing neuropathological burden, neuropsychological impairment and age. A model featuring compensated and de-compensated states of altered sterol homeostasis in MCI and AD are presented based on the current data set and our earlier in vitro work. PMID:19522732
Orbits of the visual binaries ADS 8814 and ADS 8065 from observations along a short arc
NASA Astrophysics Data System (ADS)
Kiselev, A. A.; Kiyaeva, O. V.; Romanenko, L. G.; Gorynya, N. A.
2012-07-01
The orbits of the visual binaries ADS 8814 and ADS 8065 are determined for the first time. The orbits were calculated using the parameters of the apparent motion, based on position observations along short arcs obtained on the 26-inch refrector of the Pulkovo Observatory, supplemented with radial-velocity observations for the stellar components in both pairs obtained on the 1-m telescope of the Simeiz Section of the Crimean Astrophysical Observatory. All previous visual and photographic observations of these stars after 1832 were also taken into account. The orbit of ADS 8814 was refined using the differential-correction method. The orbital periods of these two stars are about 800 and 6000 years, respectively. The mass estimates derived for the known parallaxes from the Hipparcos catalog correspond to the spectral types of these stars. The polar vectors of the obtained orbits in Galactic coordinates are also given.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-08
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Non-minimally coupled pseudoscalars in AdS4 for instantons in CFT3
NASA Astrophysics Data System (ADS)
Naghdi, M.
2016-06-01
For the 11-dimensional supergravity over {{{AdS}}}4× {{{S}}}7/{Z}k, beginning with a general four-form ansatz and the main geometry unchanged, we get a tower of massive and tachyonic pseudoscalars. Indeed, the resultant equations can be assigned to the so-called {φ }4 actions of the non-minimally coupled scalar-tensor theories with a cosmological constant. We focus on a well-known tachyonic and a new massive bulk mode, which are singlet under the internal group and break all supersymmetries, associated with skew-whiffing and Wick-rotating of the background four-form flux, respectively. The first one is the conformally coupled {m}2=-2 pseudoscalar in the bulk of Euclidean AdS4, where an exact instanton solution is found and a marginally triple-trace deformation with a proper dimension-1 operator produces an agreeing boundary solution with finite action. From the action evaluated on the solution, we estimate the decay rate of the vacuum tunneling mediated by the instanton. Another massive {m}2=+4 mode, with the so-called non-minimal coupling parameter ξ =-1/3, also breaks the conformal invariance and so there is no exact solution. Then, based on the AdS4/CFT3 correspondence rules, we propose the dimension-4 ({{{Δ }}}+=+4) boundary operator in the skew-whiffed (anti-M2-branes) theory with which to deform the boundary action—consisting of a singlet fermion, an original scalar and U(1) gauges fields—and find some solutions to be matched with the bulk solutions.
One-loop tests of the supersymmetric higher spin AdS4/CFT3 correspondence
NASA Astrophysics Data System (ADS)
Pang, Yi; Sezgin, Ergin; Zhu, Yaodong
2017-01-01
We compute one-loop free energy for D =4 Vasiliev higher spin gravities based on Konstein-Vasiliev algebras h u (m ;n |4 ) , h o (m ;n |4 ) , or h u s p (m ;n |4 ) and subject to higher spin-preserving boundary conditions, which are conjectured to be dual to the U (N ) , O (N ) or U S p (N ) singlet sectors, respectively, of free conformal field theories (CFTs) on the boundary of AdS4 . Ordinary supersymmetric higher spin theories appear as special cases of Konstein-Vasiliev theories, when the corresponding higher spin algebra contains O S p (N |4 ) as a subalgebra. In AdS4 with an S3 boundary, we use a regularization scheme for individual spins that employs their character such that the subsequent sum over all spins is finite, thereby avoiding the need for additional regularization. We find that the contribution of the infinite tower of bulk fermions vanishes. As a result, the free energy is the sum of those which arise in type A and type B models with internal symmetries, the known mismatch between the bulk and boundary free energies for type B model persists, and ordinary supersymmetric higher spin theories exhibit the mismatch as well. The only models that have a match are type A models with internal symmetries, corresponding to n =0 . The matching requires identification of the inverse Newton constant GN-1 with N plus a proper integer as was found previously for special cases. In AdS4 with an S1×S2 boundary, the bulk one-loop free energies match those of the dual free CFTs for arbitrary m and n . We also show that a supersymmetric double-trace deformation of free CFT based on O S p (1 |4 ) does not contribute to the O (N0) free energy, as expected from the bulk.
TV Ads Help Drive Testosterone Supplement Sales
... examined the ratings of these advertisements in 75 market areas across the United States, and compared them ... 2 million men with private insurance in those markets had themselves tested for low testosterone, while more ...
Ad hoc committee on global climate issues: Annual report
Gerhard, L.C.; Hanson, B.M.B.
2000-01-01
The AAPG Ad Hoc Committee on Global Climate Issues has studied the supposition of human-induced climate change since the committee's inception in January 1998. This paper details the progress and findings of the committee through June 1999. At that time there had been essentially no geologic input into the global climate change debate. The following statements reflect the current state of climate knowledge from the geologic perspective as interpreted by the majority of the committee membership. The committee recognizes that new data could change its conclusions. The earth's climate is constantly changing owing to natural variability in earth processes. Natural climate variability over recent geological time is greater than reasonable estimates of potential human-induced greenhouse gas changes. Because no tool is available to test the supposition of human-induced climate change and the range of natural variability is so great, there is no discernible human influence on global climate at this time.
NASA Astrophysics Data System (ADS)
Kemah, Elif; Akkaya, Recep; Tokgöz, Seyit Rıza
2017-02-01
In recent years, the accelerator driven subcritical reactors have taken great interest worldwide. The Accelerator Driven System (ADS) has been used to produce neutron in subcritical state by the external proton beam source. These reactors, which are hybrid systems, are important in production of clean and safe energy and conversion of radioactive waste. The ADS with the selection of reliability and robust target materials have been the new generation of fission reactors. In addition, in the ADS Reactors the problems of long-lived radioactive fission products and waste actinides encountered in the fission process of the reactor during incineration can be solved, and ADS has come to the forefront of thorium as fuel for the reactors.
Conformally related massless fields in dS, AdS and Minkowski spaces
Huguet, E.; Queva, J.; Renaud, J.
2006-04-15
In this paper we write down the equation for a scalar conformally coupled field simultaneously for de Sitter (dS), anti-de Sitter (AdS), and Minkowski spacetimes in d dimensions. The curvature dependence appears in a very simple way through a conformal factor. As a consequence the process of curvature free limit, including wave functions limit and two-points functions, turns out to be a straightforward issue. We determine a set of modes, that we call de Sitter plane waves, which become ordinary plane waves when the curvature vanishes.
Art as an Evolutionary Adaptation: Inspiration from the Visible Supernovae of AD 1054 and AD 3054
NASA Astrophysics Data System (ADS)
Corbally, C. J.; Rappaport, M. B.
2016-01-01
The authors, an astronomer/priest and an anthropologist/biologist, describe their use of the dramatic arts at the INSAP VIII meeting in their performance of two short skits on the sighting of a supernova in AD 1054 (creating the beautiful Crab Nebula) and a future “Rho Cas” stellar explosion in the constellation Cassiopeia, in AD 3054. They speculate on the emergence of science, religion, and art as bona fide adaptations, responding to natural selection, which served early hominins well in their struggle for existence. They draw parallels to the continued functions of science, religion, and art in modern society.
Phantom Accretion onto the Schwarzschild AdS Black Hole with Topological Defect
NASA Astrophysics Data System (ADS)
Amani, Ali R.; Farahani, H.
2012-09-01
In this paper, we have studied phantom energy accretion of prefect fluid onto the Schwarzschild AdS black hole with topological defect. We have obtained critical point during the accretion of fluid on the black hole where the speed of flow is equal speed of sound (Sharif and Abbas in Phantom accretion onto the Schwarzschild de-Sitter black hole, 2011, arXiv:1109.1043 [gr-qc]). The critical velocities have been computed so that the speed of fluid into the black hole is less than speed of sound. Finally, we have found that the critical point is near the black hole horizon.
Mssm-Like AdS Flux Vacua with Frozen Open-String Moduli
NASA Astrophysics Data System (ADS)
Chen, Ching-Ming; Li, Tianjun; Mayes, Van Eric; Nanopoulos, D. V.
We construct supersymmetric Pati-Salam flux vacua in AdS from intersecting D6-branes on T6/(ℤ2 × ℤ‧2). The models constructed have three generations of MSSM matter plus right-handed neutrinos. Because the cycles wrapped by the D-branes are rigid there are no extra massless fields in the adjoint representation, arising as open-string moduli. However, we find that it is problematic to break the Pati-Salam gauge symmetry to the Standard Model (SM) while keeping the SM hypercharge massless.
- criticality of AdS black hole in the Einstein-Maxwell-power-Yang-Mills gravity
NASA Astrophysics Data System (ADS)
Zhang, Ming; Yang, Zhan-Ying; Zou, De-Cheng; Xu, Wei; Yue, Rui-Hong
2015-02-01
We study the - critical behaivor of N-dimensional AdS black holes in Einstein-Maxwell-power-Yang-Mills gravity. Our results show the existence of the Van der Waals like small-large black hole phase transitions when taking some special values of charges of the Maxwell and Yang-Mills fields. Further to calculate the critical exponents of the black holes at the critical point, we find that they are the same as those in the Van der Waals liquid-gas system.
Giant magnon on deformed AdS3×S3
NASA Astrophysics Data System (ADS)
Khouchen, Malak; KlusoÅ, Josef
2014-09-01
We study giant magnon solutions for strings moving on a deformed AdS3×S3 background. We impose a conformal gauge on the Polyakov action and proceed with solving the Virasoro constraints. The expressions of the conserved charge J and the energy of a single magnon excitation are then computed. Then we determine the dispersion relation of a giant magnon in the infinite J limit configuration and we find that for κ =0 it reduces to the celebrated Hofman-Maldacena dispersion relation.
Phase Transition of AdS Black Holes with Non Linear Source in the Holographic Framework
NASA Astrophysics Data System (ADS)
Moumni, H. El
2017-02-01
In this work we investigate the phase transition of AdS black hole solution in the presence of a generalized Maxwell theory, namely power Maxwell invariant (PMI). This phase structure is probed by the nonlocal observables such as holographic entanglement entropy and two point correlation function. We show that the both observables exhibit a Van der Waals-like phase transition as the case of the thermal entropy. By checking the Maxwell's equal area law for different space dimension n and nonlinearity parameter s we confirm this result.
Adding crumb rubber into exterior wall materials.
Zhu, Han; Thong-On, Norasit; Zhang, Xiong
2002-10-01
In Arizona US, most houses are built with walls covered by stuccos/coatings/mortars. This paper presents an explorative investigation of adding crumb rubber into stuccos/coatings/mortars. A series of experiments are conducted to examine the thermal and mechanical performance of the crumb rubber mixes. The results show that, the mixes with crumb rubber do exhibit more desirable performances like being high in crack-resistance and thermal insulation, and low in thermal expansion/contraction. The drawback for the crumb rubber mixes is the reduction in compressive strength, but which can be compensated by other means. As a site experiment, an area of 100 square-feet of crumb rubber coatings for two mix designs is sprayed on a tire-adobe wall. After being sprayed more than 14 months, the coatings apparently are in good condition. Significance of this study is that this practice, if accepted, will yield improved products that consume large quantities of crumb rubber.
Spin Filtering Studies at COSY and AD
Nass, Alexander
2009-08-04
The high physics potential of experiments with stored high-energy polarized antiprotons led to the proposal of PAX (Polarized Antiproton eXperiment) for the High Energy Storage Ring (HESR) of the FAIR at GSI (Darmstadt/Germany). It is proposed to polarize a stored antiproton beam by means of spin filtering with a polarized H (D) gas target. The feasibility of spin filtering has been demonstrated in the FILTEX experiment. The current interpretation foresees a self-cancellation of the electron contribution to the filtering process and only the hadronic contribution is effective. Several experimental studies with protons (at COSY/Juelich) as well as antiprotons (at AD/CERN) will be carried out to test the principle and measure p-barp-vector and p-bard-vector cross sections. A polarized internal gas target (PIT) with surrounding Silicon detectors immersed into a low-beta section has to be set up.
The ADS Abstract Service: One Year Old
NASA Astrophysics Data System (ADS)
Grant, C. Stern; Kurtz, M. J.; Eichhorn, G.
1994-05-01
One year after its initial release the ADS Abstract Service has become quite widely used. More than 1000 different people use it per month, making about 20,000 queries and obtaining a couple of hundred thousand pieces of bibliographic information. In February a WWW connection was released, it has been heavily used. The collaboration with SIMBAD, released in January, allows one to make complex queries about work on particular objects. For example one may search for all papers which SIMBAD says are about M87, and which contain the words ``globular cluster'' in the abstract, thus getting the 65 papers on the M87 globular cluster system. One can also look for papers which have the words ``M87 globular clusters'' in the abstract, but are not listed in SIMBAD; this obtains another 19 papers, mostly conference procedings, about the M87 globular cluster system. The figure shows the list of non-SIMBAD papers.
MR enterography: how to deliver added value.
Dillman, Jonathan R; Trout, Andrew T; Smith, Ethan A
2016-05-01
MR enterography (MRE) is increasingly vital to the diagnosis and follow-up of children with Crohn disease. This diagnostic test, which can provide valuable information regarding the presence of intestinal inflammation, intestinal and intra-abdominal complications, and extra-intestinal disease-related manifestations, has the potential to directly impact both medical and surgical decision-making. Consequently, it is imperative that the interpretation and reporting of these examinations provide as much clinical information as possible. This article reviews specific ways radiologists can provide added value when interpreting MRE examinations in the setting of pediatric Crohn disease by (1) establishing the true extent of disease involvement, (2) subjectively and objectively assessing response to medical treatment and (3) accurately characterizing disease-related complications.
Total synthesis of zyzzyanones A-D
Nadkarni, Dwayaja H.; Murugesan, Srinivasan
2013-01-01
Zyzzyanones A-D is a group of biologically active marine alkaloids isolated from Australian marine sponge Zyzzya fuliginosa. They contain a unique bispyrroloquinone ring system as the core structure. The first total synthesis of all four zyzzyanones is described here. The synthesis of these alkaloids started from a previously known 6-benzylamino indole-4,7-quinone derivative and involves 6–7 steps. The key step in the synthesis involves the construction of a pyrrole ring in one step using a Mn(OAc)3 mediated oxidative free radical cyclization reaction of a 6-benzylamino indole-4,7-quinone derivative with 4-benzyloxyphenyl acetaldehyde diethyl acetal in CH3CN. PMID:23956468
Aerosol Best Estimate Value-Added Product
Flynn, C; Turner, D; Koontz, A; Chand, D; Sivaraman, C
2012-07-19
The objective of the Aerosol Best Estimate (AEROSOLBE) value-added product (VAP) is to provide vertical profiles of aerosol extinction, single scatter albedo, asymmetry parameter, and Angstroem exponents for the atmospheric column above the Central Facility at the ARM Southern Great Plains (SGP) site. We expect that AEROSOLBE will provide nearly continuous estimates of aerosol optical properties under a range of conditions (clear, broken clouds, overcast clouds, etc.). The primary requirement of this VAP was to provide an aerosol data set as continuous as possible in both time and height for the Broadband Heating Rate Profile (BBHRP) VAP in order to provide a structure for the comprehensive assessment of our ability to model atmospheric radiative transfer for all conditions. Even though BBHRP has been completed, AEROSOLBE results are very valuable for environmental, atmospheric, and climate research.
Droplet Number Concentration Value-Added Product
Riihimaki, L.; McFarlane, S.; Sivaraman, C.
2014-06-01
The ndrop_mfrsr value-added product (VAP) provides an estimate of the cloud droplet number concentration of overcast water clouds retrieved from cloud optical depth from the multi-filter rotating shadowband radiometer (MFRSR) instrument and liquid water path (LWP) retrieved from the microwave radiometer (MWR). When cloud layer information is available from vertically pointing lidar and radars in the Active Remote Sensing of Clouds (ARSCL) product, the VAP also provides estimates of the adiabatic LWP and an adiabatic parameter (beta) that indicates how divergent the LWP is from the adiabatic case. quality control (QC) flags (qc_drop_number_conc), an uncertainty estimate (drop_number_conc_toterr), and a cloud layer type flag (cloud_base_type) are useful indicators of the quality and accuracy of any given value of the retrieval. Examples of these major input and output variables are given in sample plots in section 6.0.
Spin Filtering Studies at COSY and AD
NASA Astrophysics Data System (ADS)
Nass, Alexander
2009-08-01
The high physics potential of experiments with stored high-energy polarized antiprotons led to the proposal of PAX (Polarized Antiproton eXperiment) [1] for the High Energy Storage Ring (HESR) of the FAIR at GSI (Darmstadt/Germany). It is proposed to polarize a stored antiproton beam by means of spin filtering with a polarized H (D) gas target. The feasibility of spin filtering has been demonstrated in the FILTEX experiment. The current interpretation foresees a self-cancellation of the electron contribution to the filtering process and only the hadronic contribution is effective. Several experimental studies with protons (at COSY/Jülich) as well as antiprotons (at AD/CERN) will be carried out to test the principle and measure p¯p⃗ and p¯d⃗ cross sections. A polarized internal gas target (PIT) with surrounding Silicon detectors immersed into a low-β section has to be set up.
Pirttilä, T; Koivisto, K; Mehta, P D; Reinikainen, K; Kim, K S; Kilkku, O; Heinonen, E; Soininen, H; Riekkinen, P; Wisniewski, H M
1998-06-12
Levels of soluble amyloid beta protein (sAbeta), amyloid beta precursor protein (APP) and apolipoprotein E (apoE) were examined in cerebrospinal fluid (CSF) obtained twice, at baseline and after 3-year follow-up, from 25 patients with probable Alzheimer's disease (AD). Levels of sAbeta and apoE from patients with the apoE4 allele decreased with time, whereas the levels were similar in patients without apoE4 allele. Changes of sAbeta and apoE concentrations correlated significantly with those of mini-mental state examination (MMSE) scores. Levels of sAbeta did not change with time in patients with mild dementia, whereas they decreased significantly in patients with moderate dementia. ApoE concentrations decreased in both groups whereas APP levels were similar. We conclude that measurements of CSF sAbeta and apoE levels may be helpful in monitoring progression of the disease.
Almkvist, Ove; Kadir, Ahmadul; Nordberg, Agneta
2015-01-01
The degree of abnormality and rate of change in cognitive functions, positron emission tomography Pittsburg compound B (PET PIB), and fluorodeoxyglucose (FDG) measures were studied for 8 years in an autopsy-confirmed Alzheimer's disease (AD) patient, who died 61 years old (Mini-Mental State Examination (MMSE) score 7). At first encounter with medical care, the patient was very mildly demented (MMSE score 27). She had four cognitive assessments and two examinations with PET PIB and FDG in 23 bilateral brain regions. The onset of cognitive decline was retrospectively estimated to have started in the early forties. The degree of impairment was inversely related to the rate of decline. A similar relationship was seen between the rate of change and the level of abnormality in both PIB and FDG. To conclude, rate of change in cognition, PIB, and FDG was associated with the degree of abnormality.
Kang, Yahui; Cappella, Joseph N; Fishbein, Martin
2009-09-01
This study explored the possible negative impact of a specific ad feature-marijuana scenes-on adolescents' perceptions of ad effectiveness. A secondary data analysis was conducted on adolescents' evaluations of 60 anti-marijuana public service announcements that were a part of national and state anti-drug campaigns directed at adolescents. The major finding of the study was that marijuana scenes in anti-marijuana public service announcements negatively affected ad liking and thought valence toward the ads among adolescents who were at higher levels of risk for marijuana use. This negative impact was not reversed in the presence of strong anti-marijuana arguments. The results may be used to partially explain the lack of effectiveness of the anti-drug media campaign. It may also help researchers design more effective anti-marijuana ads by isolating adverse elements in the ads that may elicit boomerang effects in the target population.
ADS-B and multilateration sensor fusion algorithm for air traffic control
NASA Astrophysics Data System (ADS)
Liang, Mengchen
Air traffic is expected to increase rapidly in the next decade. But, the current Air Traffic Control (ATC) system does not meet the demand of the future safety and efficiency. The Next Generation Air Transportation System (NextGen) is a transformation program for the ATC system in the United States. The latest estimates by Federal Aviation Administration (FAA) show that by 2018 NextGen will reduce total delays in flight by 35 percent and provide 23 billion dollars in cumulative benefits. A satellite-based technology called the Automatic Dependent Surveillance-Broadcast (ADS-B) system is one of the most important elements in NextGen. FAA expects that ADS-B systems will be available in the National Airspace System (NAS) by 2020. However, an alternative surveillance system is needed due to vulnerabilities that exist in ADS-B systems. Multilateration has a high accuracy performance and is believed to be an ideal back-up strategy for ADS-B systems. Thus, in this study, we develop the ADS-B and multilateration sensor fusion algorithm for aircraft tracking applications in ATC. The algorithm contains a fault detection function for ADS-B information monitoring by using Trajectory Change Points reports from ADS-B and numerical vectors from a hybrid estimation algorithm. We consider two types of faults in the ADS-B measurement model to show that the algorithm is able to deal with the bad data from ADS-B systems and automatically select good data from multilateration systems. We apply fuzzy logic concepts and generate time variant parameters during the fusion process. The parameters play a role of weights for combining data from different sensors. The algorithm performance is validated through two aircraft tracking examples.
Exploring the bulk in AdS /CFT : A covariant approach
NASA Astrophysics Data System (ADS)
Engelhardt, Netta
2017-03-01
I propose a general, covariant way of defining when one region is "deeper in the bulk" than another. This definition is formulated outside of an event horizon (or in the absence thereof) in generic geometries; it may be applied to both points and surfaces, and it may be used to compare the depth of bulk points or surfaces relative to a particular boundary subregion or relative to the entire boundary. Using the recently proposed "light-cone cut" formalism, the comparative depth between two bulk points can be determined from the singularity structure of Lorentzian correlators in the dual field theory. I prove that, by this definition, causal wedges of progressively larger regions probe monotonically deeper in the bulk. The definition furthermore matches expectations in pure AdS and in static AdS black holes with isotropic spatial slices, where a well-defined holographic coordinate exists. In terms of holographic renormalization group flow, this new definition of bulk depth makes contact with coarse graining over both large distances and long time scales.
Exact results for the low energy AdS 4 × 3 string theory
NASA Astrophysics Data System (ADS)
Fabbri, Alessandro; Fioravanti, Davide; Piscaglia, Simone; Tateo, Roberto
2013-11-01
We derive the Thermodynamic Bethe Ansatz equations for the relativistic sigma model describing the AdS 4 × 3 string II A theory at strong coupling (i.e. in the Alday-Maldacena decoupling limit). The corresponding Y -system involves an infinite number of Y functions and is of a new type, although it shares a peculiar feature with the Y -system for AdS 4 × 3. A truncation of the equations at level p and a further generalisation to generic rank N allow us an alternative description of the theory as the N =4, p = ∞ representative in an infinite family of models corresponding to the conformal cosets ( N -1) p × U(1), perturbed by a relevant composite field ϕ ( N,p) = ϕ[( N -1) p ] × ϕ [U(1)] that couples the two independent conformal field theories. The calculation of the ultraviolet central charge confirms the conjecture by Basso and Rej and the conformal dimension of the perturbing operator, at every N and p, is obtained using the Y-system periodicity. The conformal dimension of ϕ[( N -1) p ] matches that of the field identified by Fendley while discussing integrability issues for the purely bosonic N -1 sigma model.
Baldcypress tree ring elemental concentrations at Reelfoot Lake, Tennessee from AD 1795 to AD 1820
Van Arsdale, R.; Hall, G.
1995-11-01
Many two hundred year old baldcypress trees in Reelfoot Lake, Tennessee, lived through the great New Madrid earthquakes of 1811--1812. This study was undertaken to determine if the elemental composition of baldcypress tree rings showed any systematic variation through the earthquake period of AD 1795 through AD 1820. Multiple cores were collected from two Reelfoot Lake baldcypress trees and analyzed using Inductively Coupled Plasma Mass Spectrometry (ICP-MS). Individual yearly rings and five-year ring segments were analyzed to determine their elemental compositions. The cores were analyzed for Li through U but only Ba, Ce, Cs, Cu, I, La, Mg, Mn, Nd, Rb, Sm, Sr, and Zn were found to be in appropriate concentrations for this study. Of these elements only Ce, I, La, Nd, Rb, and Sm showed any systematic changes within individual cores. Comparison of three cores taken from one tree reveal that tree-ring elemental concentrations and changes in tree-ring elemental concentration through time are very different among the cores. When comparing the elemental concentrations of tree rings for the same years in the two different trees neither elemental concentrations nor changes in elemental concentration through time were similar. We conclude that the elemental concentrations in the tree rings of the two baldcypress trees analyzed in this study show no systematic change through the earthquake period of AD 1795 through AD 1820.
Quasinormal modes and holographic correlators in a crunching AdS geometry
NASA Astrophysics Data System (ADS)
Kumar, S. Prem; Vaganov, Vladislav
2016-02-01
We calculate frequency space holographic correlators in an asymptotically AdS crunching background, dual to a relevant deformation of the M2-brane CFT placed in de Sitter spacetime. For massless bulk scalars, exploiting the connection to a solvable supersymmetric quantum mechanical problem, we obtain the exact frequency space correlator for the dual operator in the deformed CFT. Controlling the shape of the crunching surface in the Penrose diagram by smoothly dialling the deformation from zero to infinity, we observe that in the large deformation limit the Penrose diagram becomes a `square', and the exact holographic correlators display striking similarities to their counterparts in the BTZ black hole and its higher dimensional generalisations. We numerically determine quasinormal poles for relevant and irrelevant operators, and find an intricate pattern of these in the complex frequency plane. In the case of relevant operators, the deformation parameter has an infinite sequence of critical values, each one characterised by a pair of poles colliding and moving away from the imaginary frequency axis with increasing deformation. In the limit of infinite deformation all scalar operators have identical quasinormal spectra. We compare and contrast our strongly coupled de Sitter QFT results with strongly coupled thermal correlators from AdS black holes.
Wilson loops in N = 4 gauge theory and fundamental strings in AdS
NASA Astrophysics Data System (ADS)
Drukker, Nadav
The AdS/CFT correspondence is a duality between large N SU(N) gauge theory with N = 4 supersymmetry in 4 dimensions at strong coupling and type IIB string theory on AdS5 × S 5. According to the duality, Wilson loops are given by large fundamental strings in the AdS background. This dissertation examines various aspects of this relation. There is a distinguished class of loops, which are the natural Wilson loop observables in this theory. The magnitude of their coupling to the gauge fields and the scalars is equal. We explore some of their properties, in particular, we show that their expectation values are free from ultra-violet divergence. At strong coupling those Wilson loops can be evaluated by a saddle point expansion around classical solutions of string theory, or minimal surfaces. At the classical level we conclude that the action is not the area of the surface, which is divergent, but a Legendre transform of it. At one loop in the worldsheet expansion, we develop a systematic approach to the study of semiclassical fluctuations of strings in AdS 5 × S5 based on the Green-Schwarz formalism. We show that the string partition function is well defined and finite, and issues related to different gauge choices are clarified. We study four types of loops with different geometries. A single straight line is a BPS object and the corresponding Wilson loop is one. We show this in perturbation theory at weak coupling and to one loop order at strong coupling. A circular Wilson loop is similar to a straight line, but is not BPS, and it's expectation value is not one. A particularly interesting observable is a pair of anti parallel lines. Those give the potential between two W- bosons. Another minimal surface we can find is for loops with cusps or intersections. We also discuss the zig-zag symmetry of the loop operator. In the N = 4 gauge theory the zig-zag symmetry holds when the loop does not couple to the scalar fields. We show how this is realized by formal derivation
RG flow and thermodynamics of causal horizons in higher-derivative AdS gravity
NASA Astrophysics Data System (ADS)
Banerjee, Shamik; Bhattacharyya, Arpan
2016-05-01
In
Value-Added Model (VAM) Research for Educational Policy: Framing the Issue
ERIC Educational Resources Information Center
Amrein-Beardsley, Audrey; Collins, Clarin; Polasky, Sarah A.; Sloat, Edward F.
2013-01-01
In this manuscript, the guest editors of the EPAA Special Issue on "Value-Added Model (VAM) Research for Educational Policy" (1) introduce the background and policy context surrounding the increased use of VAMs for teacher evaluation and accountability purposes across the United States; (2) summarize the five research papers and one…
ERIC Educational Resources Information Center
Goldring, Ellen; Grissom, Jason A.; Rubin, Mollie; Neumerski, Christine M.; Cannata, Marisa; Drake, Timothy; Schuermann, Patrick
2015-01-01
Increasingly, states and districts are combining student growth measures with rigorous, rubric-aligned teacher observations in constructing teacher evaluation measures. Although the student growth or value-added components of these measures have received much research and policy attention, the results of this study suggest that the data generated…
The Sensitivity of Value-Added Modeling to the Creation of a Vertical Score Scale
ERIC Educational Resources Information Center
Briggs, Derek C.; Weeks, Jonathan P.
2009-01-01
The purpose of this study was to evaluate the sensitivity of growth and value-added modeling to the way an underlying vertical score scale has been created. Longitudinal item-level data were analyzed with both student- and school-level identifiers for the entire state of Colorado between 2003 and 2006. Eight different vertical scales were…
Assessing the Added Value of Dynamical Downscaling Using the Standardized Precipitation Index
In this study, the Standardized Precipitation Index (SPI) is used to ascertain the added value of dynamical downscaling over the contiguous United States. WRF is used as a regional climate model (RCM) to dynamically downscale reanalysis fields to compare values of SPI over drough...
Zhou, Bo; Yao, Hongxiang; Wang, Pan; Zhang, Zengqiang; Zhan, Yafeng; Ma, Jianhua; Xu, Kaibin; Wang, Luning; An, Ningyu; Liu, Yong; Zhang, Xi
2015-01-01
The purpose of our study was to investigate whether the whole-brain functional connectivity pattern exhibits disease severity-related alterations in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI). Resting-state functional magnetic resonance imaging data were acquired in 27 MCI subjects, 35 AD patients, and 27 age- and gender-matched subjects with normal cognition (NC). Interregional functional connectivity was assessed based on a predefined template which parcellated the brain into 90 regions. Altered whole-brain functional connectivity patterns were identified via connectivity comparisons between the AD and NC subjects. Finally, the relationship between functional connectivity strength and cognitive ability according to the mini-mental state examination (MMSE) was evaluated in the MCI and AD groups. Compared with the NC group, the AD group exhibited decreased functional connectivities throughout the brain. The most significantly affected regions included several important nodes of the default mode network and the temporal lobe. Moreover, changes in functional connectivity strength exhibited significant associations with disease severity-related alterations in the AD and MCI groups. The present study provides novel evidence and will facilitate meta-analysis of whole-brain analyses in AD and MCI, which will be critical to better understand the neural basis of AD.
AdS/CFT beyond the unitarity bound
NASA Astrophysics Data System (ADS)
Andrade, Tomás; Marolf, Donald
2012-01-01
Scalars in AdS d+1 with squared masses in the Breitenlohner-Freedman window - {d^{{2}}}/{4} ≤slant {m^{{2}}} < - {d^{{2}}}/{4} + {1} (in units with the AdS scale ℓ set to 1) are known to enjoy a variety of boundary conditions. For larger masses {m^{{2}}} > - {d^{{2}}}/{4} + {1} , unitarity bounds in possible dual CFTs suggest that such general boundary conditions should lead to ghosts. We show that this is not always the case as, for conformally-invariant boundary conditions in Poincaré AdS that would naively violate unitarity bounds, the system is generically ghost-free. Conflicts with unitarity bounds are avoided due to the presence of unexpected pure gauge modes and an associated infrared divergence. The expected ghosts appear when the IR divergence is removed either by deforming these boundary conditions or considering global AdS.
Space-Time Processing for Tactical Mobile Ad Hoc Networks
2008-08-01
Maximization in Multi-User, MIMO Channels with Linear Processing...58 2.9 Using Feedback in Ad Hoc Networks....................................................................65 2.10 Feedback MIMO ...in MIMO Ad Hoc Interference Networks.......................................................................................................75 2.12
Modelling of Medium Access Control (MAC) Protocols for Mobile Ad-Hoc Networks
2005-06-01
Slot IP Internet Protocol LAN Local Area Network MAC Medium Access Control MACAW Medium Access Protocol for Wireless LANs MANET Mobile Ad-hoc...Unforced state – It waits after entering the state until it is invoked by another process or an interrupt. It is in dark grey on this report, and red ... green in OPNET. A MAC process model is built for general initialisations of the MAC module, and to invoke the selected MAC protocol process model
Is It Counting, or Is It Adding?
ERIC Educational Resources Information Center
Eisenhardt, Sara; Fisher, Molly H.; Thomas, Jonathan; Schack, Edna O.; Tassell, Janet; Yoder, Margaret
2014-01-01
The Common Core State Standards for Mathematics (CCSSI 2010) expect second grade students to "fluently add and subtract within 20 using mental strategies" (2.OA.B.2). Most children begin with number word sequences and counting approximations and then develop greater skill with counting. But do all teachers really understand how this…
Active Duty (AD) Claims Payment Program
1991-08-26
Claims Payment Program References: (a) Sections 1073 and 1074(c) of title 10, United States Code (b) DoD 6010.8-R, "Civilian Health and Medical Program...Provider) 1. This payment was calculated under the CHAMPUS DRG-based payment system as directed by Sections 1073 and 1074(c) of title 10, United
Certification Synergy: Adding Value to the Curriculum.
ERIC Educational Resources Information Center
Nickoli, Rebecca; Keen, Mark
Ivy Tech State College (Indiana) is the statewide two-year college system in Indiana, with 23 campuses and a fall 2002 enrollment of 64,110 credit students and approximately 13,000 non-credit students. Ivy Tech has a long history of offering certification training and, in some cases, testing, in a variety of areas from health to business and…
ADDING ECOLOGICAL REALISM TO PLANT TESTING
Current test protocols for the protection of nontarget plants used when registering pesticides in the United States and many other countries depend on two tests using greenhouse grown, agricultural seedling plants. The seedling emergence and vegetative vigor tests are used to as...
Radio Decameter Observations of AD Leonis
NASA Astrophysics Data System (ADS)
Leitzinger, M.; Odert, P., Hanslmeier, A.; Konovalenko, A. A.; Vanko, M.; Lammer, H.; Khodachenko, M. I.; Rucker, H. O.
AD Leonis is known to be an active flaring star of spectral type M4.5 Ve. The World's largest decameter array, the UTR-2 near Kharkov/Ukraine of the Ukrainian Academy of Sciences, was monitoring this star for ten nights during February 2007. A Digital Spectro-Polarimeter (DSP) was used as back-end facility giving the possibility of investigating dynamic spectra. These spectra are very useful when searching for decameter radio type II bursts, which show a slow frequency drift with time and are known to be correlated with Coronal Mass Ejections (CMEs) on the Sun. Since the drift in frequency is correlated with the density of the material through which the shock wave propagates, we can use this also as a proxy for e.g. density changes for stellar wind investigations. We are able to discriminate between stellar and artificial emission using the instrument's multibeam capability. Averaging techniques are also applied to make possible bursts detectable. The main intention is the search for stellar analogues of the solar type II bursts as signatures of CMEs, but also for periodic structures. Preliminary results are presented.
Radio decameter observations of AD Leonis
NASA Astrophysics Data System (ADS)
Leitzinger, M.; Odert, P.; Hanslmeier, A.; Konovalenko, A. A.; Vanko, M.; Khodachenko, M.; Lammer, H.; Rucker, H. O.
2007-08-01
AD Leonis is known to be an active flaring star of spectral type M4.5 Ve. The world's largest decamter array, the UTR-2 near Kharkov/Ukraine of the Ukrainian Academy of Scienecs, was monitoring this star for ten nights during February of this year. A Digital Spectro Polarimeter (DSP) was used as back-end facility giving the possibility of investigating dynamic spectra. These spectra are very useful when searching for decameter radio type II bursts, which show a slow frequency drift with time and are known to be correlated with Coronal Mass Ejections (CMEs) on the sun. Since the drift in frequency is correlated with the density of the material through which the shock wave propagates, we can use this also as a proxy for e.g. density changes for stellar wind investigations. We are able to discriminate between stellar and artificial emission using the instrument's multibeam capability. Also averaging techniques are applied to make possible bursts detectable. The main intention is the search for stellar analogues of the solar type II bursts as signatures of CMEs, but also for periodic structures. Preliminary results are presented.
Spontaneous Ad Hoc Mobile Cloud Computing Network
Lacuesta, Raquel; Sendra, Sandra; Peñalver, Lourdes
2014-01-01
Cloud computing helps users and companies to share computing resources instead of having local servers or personal devices to handle the applications. Smart devices are becoming one of the main information processing devices. Their computing features are reaching levels that let them create a mobile cloud computing network. But sometimes they are not able to create it and collaborate actively in the cloud because it is difficult for them to build easily a spontaneous network and configure its parameters. For this reason, in this paper, we are going to present the design and deployment of a spontaneous ad hoc mobile cloud computing network. In order to perform it, we have developed a trusted algorithm that is able to manage the activity of the nodes when they join and leave the network. The paper shows the network procedures and classes that have been designed. Our simulation results using Castalia show that our proposal presents a good efficiency and network performance even by using high number of nodes. PMID:25202715
Droplet Number Concentration Value Added Product
Chitra Sivaraman, PNNL
2015-08-06
Cloud droplet number concentration is an important factor in understanding aerosol-cloud interactions. As aerosol concentration increases, it is expected that droplet number concentration (Nd) will increase and droplet size will decrease, for a given liquid water path. This will greatly affect cloud albedo as smaller droplets reflect more shortwave radiation; however, the magnitude and variability of these processes under different environmental conditions is still uncertain.McComiskey et al. (2009) have implemented a method, based onBoers and Mitchell (1994), for calculating Nd from ground-based remote sensing measurements of optical depth and liquid water path. They show that the magnitude of the aerosol-cloud interactions (ACI) varies with a range of factors, including the relative value of the cloud liquid water path (LWP), the aerosol size distribution, and the cloud updraft velocity. Estimates of Nd under a range of cloud types and conditions and at a variety of sites are needed to further quantify the impacts of aerosol cloud interactions. In order to provide data sets for studying aerosol-cloud interactions, the McComiskey et al. (2009) method was implemented as the Droplet Number Concentration (NDROP) value-added product (VAP).
Spontaneous ad hoc mobile cloud computing network.
Lacuesta, Raquel; Lloret, Jaime; Sendra, Sandra; Peñalver, Lourdes
2014-01-01
Cloud computing helps users and companies to share computing resources instead of having local servers or personal devices to handle the applications. Smart devices are becoming one of the main information processing devices. Their computing features are reaching levels that let them create a mobile cloud computing network. But sometimes they are not able to create it and collaborate actively in the cloud because it is difficult for them to build easily a spontaneous network and configure its parameters. For this reason, in this paper, we are going to present the design and deployment of a spontaneous ad hoc mobile cloud computing network. In order to perform it, we have developed a trusted algorithm that is able to manage the activity of the nodes when they join and leave the network. The paper shows the network procedures and classes that have been designed. Our simulation results using Castalia show that our proposal presents a good efficiency and network performance even by using high number of nodes.
AdS/QCD at finite density and temperature
Kim, Y.
2012-07-15
We review some basics of AdS/QCD following a non-standard path and list a few results from AdS/QCD or holographic QCD. The non-standard path here is to use the analogy of the way one obtains an effective model of QCD like linear sigma model and the procedure to construct an AdS/QCD model based on the AdS/CFT dictionary.
AD Hoc Study on Human Robot Interface Issues
2002-09-01
ARMY SCIENCE BOARD AD HOC STUDY ON HUMAN ROBOT INTERFACE ISSUES FINAL REPORT SEPTEMBER 2002 Distribution: Approved for...conclusions contained in this report are those of the 2002 Ad Hoc Study Panel on “Human- Robot Interface Issues” and do not necessarily reflect the official...DATES COVERED Army Science Board – 2002 Ad Hoc Study 4. TITLE AND SUBTITLE AD HOC STUDY ON HUMAN ROBOT INTERFACE ISSUES 6. AUTHOR(S) Study
Association of the RAGE G82S polymorphism with Alzheimer’s disease
von Otter, Malin; Sjölander, Annica; Nilsson, Staffan; Minthon, Lennart; Gustafson, Deborah R.; Skoog, Ingmar; Blennow, Kaj; Zetterberg, Henrik
2010-01-01
The receptor for advanced glycation end-products (RAGE) has been implicated in several pathophysiological processes relevant to Alzheimer’s disease (AD), including transport and synaptotoxicity of AD-associated amyloid β (Aβ) peptides. A recent Chinese study (Li et al. in J Neural Transm 117:97–104, 2010) suggested an association between the 82S allele of the functional single nucleotide polymorphism (SNP) G82S (rs2070600) in the RAGE-encoding gene AGER and risk of AD. The present study aimed to investigate associations between AGER, AD diagnosis, cognitive scores and cerebrospinal fluid AD biomarkers in a European cohort of 316 neurochemically verified AD cases and 579 controls. Aside from G82S, three additional tag SNPs were analyzed to cover the common genetic variation in AGER. The 82S allele was associated with increased risk of AD (Pc = 0.04, OR = 2.0, 95% CI 1.2–3.4). There was no genetic interaction between AGER 82S and APOE ε4 in producing increased risk of AD (P = 0.4), and none of the AGER SNPs showed association with Aβ42, T-tau, P-tau181 or mini-mental state examination scores. The data speak for a weak, but significant effect of AGER on risk of AD. PMID:20567859
Boundary stress tensor and asymptotically AdS3 non-Einstein spaces at the chiral point
NASA Astrophysics Data System (ADS)
Giribet, Gaston; Goya, Andrés; Leston, Mauricio
2011-09-01
Chiral gravity admits asymptotically AdS3 solutions that are not locally equivalent to AdS3; meaning that solutions do exist which, while obeying the strong boundary conditions usually imposed in general relativity, happen not to be Einstein spaces. In topologically massive gravity (TMG), the existence of non-Einstein solutions is particularly connected to the question about the role played by complex saddle points in the Euclidean path integral. Consequently, studying (the existence of) nonlocally AdS3 solutions to chiral gravity is relevant to understanding the quantum theory. Here, we discuss a special family of nonlocally AdS3 solutions to chiral gravity. In particular, we show that such solutions persist when one deforms the theory by adding the higher-curvature terms of the so-called new massive gravity. Moreover, the addition of higher-curvature terms to the gravity action introduces new nonlocally AdS3 solutions that have no analogues in TMG. Both stationary and time-dependent, axially symmetric solutions that asymptote AdS3 space without being locally equivalent to it appear. Defining the boundary stress tensor for the full theory, we show that these non-Einstein geometries have associated vanishing conserved charges.
14 CFR 1203.903 - Ad hoc committees.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Ad hoc committees. 1203.903 Section 1203... NASA Information Security Program Committee § 1203.903 Ad hoc committees. The Chairperson is authorized to establish such ad hoc panels or subcommittees as may be necessary in the conduct of the...
14 CFR 1203.903 - Ad hoc committees.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Ad hoc committees. 1203.903 Section 1203.903... Information Security Program Committee § 1203.903 Ad hoc committees. The Chairperson is authorized to establish such ad hoc panels or subcommittees as may be necessary in the conduct of the Committee's work....
21 CFR 14.90 - Ad hoc advisory committee members.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Ad hoc advisory committee members. 14.90 Section... PUBLIC HEARING BEFORE A PUBLIC ADVISORY COMMITTEE Members of Advisory Committees § 14.90 Ad hoc advisory committee members. In selecting members of an ad hoc advisory committee, the Commissioner may use...
25 CFR 11.904 - Guardian ad litem.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 25 Indians 1 2011-04-01 2011-04-01 false Guardian ad litem. 11.904 Section 11.904 Indians BUREAU... ORDER CODE Children's Court § 11.904 Guardian ad litem. The children's court, under any proceeding authorized by this part, shall appoint, for the purposes of the proceeding, a guardian ad litem for a...
21 CFR 14.90 - Ad hoc advisory committee members.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Ad hoc advisory committee members. 14.90 Section... PUBLIC HEARING BEFORE A PUBLIC ADVISORY COMMITTEE Members of Advisory Committees § 14.90 Ad hoc advisory committee members. In selecting members of an ad hoc advisory committee, the Commissioner may use...
25 CFR 11.904 - Guardian ad litem.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 25 Indians 1 2010-04-01 2010-04-01 false Guardian ad litem. 11.904 Section 11.904 Indians BUREAU... ORDER CODE Children's Court § 11.904 Guardian ad litem. The children's court, under any proceeding authorized by this part, shall appoint, for the purposes of the proceeding, a guardian ad litem for a...
Determining Positions and Desired Applicant Characteristics in Sports Job Ads
ERIC Educational Resources Information Center
Atali, Levent
2015-01-01
The purpose of this study is to determine the diversity of positions occurring in sports job ads and reveal the characteristics requested from applicants for each position. This study examined 103 sports-related job ads obtained from four human resources websites. Using content analysis, job ads were examined in terms of job titles, and the…
Evaluating Teachers: The Important Role of Value-Added
ERIC Educational Resources Information Center
Glazerman, Steven; Loeb, Susanna; Goldhaber, Dan; Staiger, Douglas; Raudenbush, Stephen; Whitehurst, Grover
2010-01-01
The evaluation of teachers based on the contribution they make to the learning of their students, "value-added", is an increasingly popular but controversial education reform policy. In this report, the authors highlight and try to clarify four areas of confusion about value-added. The first is between value-added information and the…
Leica ADS40 Sensor for Coastal Multispectral Imaging
NASA Technical Reports Server (NTRS)
Craig, John C.
2007-01-01
The Leica ADS40 Sensor as it is used for coastal multispectral imaging is presented. The contents include: 1) Project Area Overview; 2) Leica ADS40 Sensor; 3) Focal Plate Arrangements; 4) Trichroid Filter; 5) Gradient Correction; 6) Image Acquisition; 7) Remote Sensing and ADS40; 8) Band comparisons of Satellite and Airborne Sensors; 9) Impervious Surface Extraction; and 10) Impervious Surface Details.
Performance Improvement in Geographic Routing for Vehicular Ad Hoc Networks
Kaiwartya, Omprakash; Kumar, Sushil; Lobiyal, D. K.; Abdullah, Abdul Hanan; Hassan, Ahmed Nazar
2014-01-01
Geographic routing is one of the most investigated themes by researchers for reliable and efficient dissemination of information in Vehicular Ad Hoc Networks (VANETs). Recently, different Geographic Distance Routing (GEDIR) protocols have been suggested in the literature. These protocols focus on reducing the forwarding region towards destination to select the Next Hop Vehicles (NHV). Most of these protocols suffer from the problem of elevated one-hop link disconnection, high end-to-end delay and low throughput even at normal vehicle speed in high vehicle density environment. This paper proposes a Geographic Distance Routing protocol based on Segment vehicle, Link quality and Degree of connectivity (SLD-GEDIR). The protocol selects a reliable NHV using the criteria segment vehicles, one-hop link quality and degree of connectivity. The proposed protocol has been simulated in NS-2 and its performance has been compared with the state-of-the-art protocols: P-GEDIR, J-GEDIR and V-GEDIR. The empirical results clearly reveal that SLD-GEDIR has lower link disconnection and end-to-end delay, and higher throughput as compared to the state-of-the-art protocols. It should be noted that the performance of the proposed protocol is preserved irrespective of vehicle density and speed. PMID:25429415
Performance improvement in geographic routing for Vehicular Ad Hoc Networks.
Kaiwartya, Omprakash; Kumar, Sushil; Lobiyal, D K; Abdullah, Abdul Hanan; Hassan, Ahmed Nazar
2014-11-25
Geographic routing is one of the most investigated themes by researchers for reliable and efficient dissemination of information in Vehicular Ad Hoc Networks (VANETs). Recently, different Geographic Distance Routing (GEDIR) protocols have been suggested in the literature. These protocols focus on reducing the forwarding region towards destination to select the Next Hop Vehicles (NHV). Most of these protocols suffer from the problem of elevated one-hop link disconnection, high end-to-end delay and low throughput even at normal vehicle speed in high vehicle density environment. This paper proposes a Geographic Distance Routing protocol based on Segment vehicle, Link quality and Degree of connectivity (SLD-GEDIR). The protocol selects a reliable NHV using the criteria segment vehicles, one-hop link quality and degree of connectivity. The proposed protocol has been simulated in NS-2 and its performance has been compared with the state-of-the-art protocols: P-GEDIR, J-GEDIR and V-GEDIR. The empirical results clearly reveal that SLD-GEDIR has lower link disconnection and end-to-end delay, and higher throughput as compared to the state-of-the-art protocols. It should be noted that the performance of the proposed protocol is preserved irrespective of vehicle density and speed.
Topologically massive gravity and the AdS/CFT correspondence
NASA Astrophysics Data System (ADS)
Skenderis, Kostas; Taylor, Marika; van Rees, Balt C.
2009-09-01
We set up the AdS/CFT correspondence for topologically massive gravity (TMG) in three dimensions. The first step in this procedure is to determine the appropriate fall off conditions at infinity. These cannot be fixed a priori as they depend on the bulk theory under consideration and are derived by solving asymptotically the non-linear field equations. We discuss in detail the asymptotic structure of the field equations for TMG, showing that it contains leading and subleading logarithms, determine the map between bulk fields and CFT operators, obtain the appropriate counterterms needed for holographic renormalization and compute holographically one- and two-point functions at and away from the ``chiral point'' (μ = 1). The 2-point functions at the chiral point are those of a logarithmic CFT (LCFT) with cL = 0,cR = 3l/GN and b = -3l/GN, where b is a parameter characterizing different c = 0 LCFTs. The bulk correlators away from the chiral point (μ ≠ 1) smoothly limit to the LCFT ones as μ → 1. Away from the chiral point, the CFT contains a state of negative norm and the expectation value of the energy momentum tensor in that state is also negative, reflecting a corresponding bulk instability due to negative energy modes.
Dynamical probe of thermodynamical properties in three-dimensional hairy AdS black holes
NASA Astrophysics Data System (ADS)
Zou, De-Cheng; Liu, Yunqi; Zhang, Cheng-Yong; Wang, Bin
2016-11-01
We study separatively the quasinormal modes (QNM) of electromagnetic perturbations around three-dimensional anti-de Sitter (AdS) black holes in Jordan and Einstein frames, which are related by the conformal transformations and a redefinition of a scalar field. We find that, in the Jordan frame, the imaginary parts of QNM frequencies can reflect the thermodynamical stabilities of hairy black holes, including the possible phase transition between the hairy black hole and BTZ black hole, disclosed by examining the corresponding free energies. Similar results are also uncovered in the Einstein frame. The obtained results further support that the QNM can be a dynamic probe of the thermodynamic properties in black holes.
Localized AdS_{5}×S^{5} Black Holes.
Dias, Óscar J C; Santos, Jorge E; Way, Benson
2016-10-07
According to heuristic arguments, global AdS_{5}×S^{5} black holes are expected to undergo a phase transition in the microcanonical ensemble. At high energies, one expects black holes that respect the symmetries of the S^{5}; at low energies, one expects "localized" black holes that appear pointlike on the S^{5}. According to anti-de Sitter/conformal field theory correspondence, N=4 supersymmetric Yang-Mills (SYM) theory on a 3-sphere should therefore exhibit spontaneous R-symmetry breaking at strong coupling. In this Letter, we numerically construct these localized black holes. We extrapolate the location of this phase transition, and compute the expectation value of the broken scalar operator with lowest conformal dimension. Via the correspondence, these results offer quantitative predictions for N=4 SYM theory.
Resurgence of the dressing phase for AdS5 × S5
NASA Astrophysics Data System (ADS)
Arutyunov, Gleb; Dorigoni, Daniele; Savin, Sergei
2017-01-01
We discuss the resummation of the strong coupling asymptotic expansion of the dressing phase of the AdS5 × S5 superstring. The dressing phase proposed by Beisert, Eden and Staudacher can be recovered from a modified Borel-Ecalle resummation of this asymptotic expansion only by completing it with new, non-perturbative and exponentially suppressed terms that can be organized into different sectors labelled by an instanton-like number. We compute the contribution to the dressing phase coming from the sum over all the instanton sectors and show that it satisfies the homogeneous crossing symmetry equation. We comment on the semiclassical origin of the non-perturbative terms from the world-sheet theory point of view even though their precise explanation remains still quite mysterious.
Thermodynamic geometry and phase transitions of dyonic charged AdS black holes
NASA Astrophysics Data System (ADS)
Chaturvedi, Pankaj; Das, Anirban; Sengupta, Gautam
2017-02-01
We investigate phase transitions and critical phenomena of four dimensional dyonic charged AdS black holes in the framework of thermodynamic geometry. In a mixed canonical-grand canonical ensemble with a fixed electric charge and varying magnetic charge these black holes exhibit a liquid-gas like first order phase transition culminating in a second order critical point similar to the van der Waals gas. We show that the thermodynamic scalar curvature R for these black holes follow our proposed geometrical characterization of the R-crossing Method for the first order liquid-gas like phase transition and exhibits a divergence at the second order critical point. The pattern of R crossing and divergence exactly corresponds to those of a van der Waals gas described by us in an earlier work.
Holographic antiferromagnetic quantum criticality and AdS2 scaling limit
NASA Astrophysics Data System (ADS)
Cai, Rong-Gen; Yang, Run-Qiu; Kusmartsev, F. V.
2015-08-01
A holographic description on the antiferromagnetic quantum phase transition (QPT) induced by the magnetic field and the criticality in the vicinity of the quantum critical point have been investigated numerically recently. In this paper, we show that the properties of QPT in this holographic model are governed by a CFT dual to the emergent AdS2 in the IR region, which confirms that the dual boundary theory is a strong coupling theory with dynamic exponent z =2 and logarithmic corrections appearing. We also compare them with the results from the Hertz model by solving the RG equation at its upper critical dimension and with some experimental data from pyrochlores Er2 -2 xY2 xTi2 O7 and BiCoPO5 .
Holographic cusped Wilson loops in q-deformed AdS5 × S5 spacetime
NASA Astrophysics Data System (ADS)
Bai, Nan; Chen, Hui-Huang; Wu, Jun-Bao
2015-10-01
In this paper, a minimal surface in q-deformed AdS5×S5 with a cusp boundary is studied in detail. This minimal surface is dual to a cusped Wilson loop in dual field theory. We find that the area of the minimal surface has both logarithmic squared divergence and logarithmic divergence. The logarithmic squared divergence cannot be removed by either Legendre transformation or the usual geometric subtraction. We further make an analytic continuation to the Minkowski signature, taking the limit such that the two edges of the cusp become light-like, and extract the anomalous dimension from the coefficient of the logarithmic divergence. This anomalous dimension goes back smoothly to the results in the undeformed case when we take the limit that the deformation parameter goes to zero. Supported by National Natural Science Foundation of China (11105154, 11222549, 11275207), K. C. Wong Education Foundation and Youth Innovation Promotion Association of CAS
Massless sector of AdS3 superstrings: A geometric interpretation
NASA Astrophysics Data System (ADS)
Fontanella, Andrea; Torrielli, Alessandro
2016-09-01
We study the recently discovered q -deformed Poincaré supersymmetry of the AdS3/CFT2 integrable massless scattering, and demonstrate how the S -matrix is invariant under boosts. The boost generator has a nonlocal coproduct, which acts on the scattering matrix as a differential operator, annihilating it. We propose to reinterpret the boost action in terms of covariant derivatives on bundles, and derive an expression for the S -matrix as the path-ordered exponential of a flat connection. We provide a list of possible alternative interpretations of this emergent geometric picture, including a one-dimensional auxiliary Schrödinger problem. We support our claims by performing a simplified algebraic Bethe ansatz, which bears some resemblance to antiferromagnets.
Holographic fermionic spectrum from Born-Infeld AdS black hole
NASA Astrophysics Data System (ADS)
Wu, Jian-Pin
2016-07-01
In this letter, we systematically explore the holographic (non-)relativistic fermionic spectrum without/with dipole coupling dual to Born-Infeld anti-de Sitter (BI-AdS) black hole. For the relativistic fermionic fixed point, this holographic fermionic system exhibits non-Fermi liquid behavior. Also, with the increase of BI parameter γ, the non-Fermi liquid becomes even ;more non-Fermi;. When the dipole coupling term is included, we find that the BI term makes it a lot tougher to form the gap. While for the non-relativistic fermionic system with large dipole coupling in BI-AdS background, with the increase of BI parameter, the gap comes into being again.
Charge loss (or the lack thereof) for AdS black holes
NASA Astrophysics Data System (ADS)
Ong, Yen Chin; Chen, Pisin
2014-06-01
The evolution of evaporating charged black holes is complicated to model in general, but is nevertheless important since the hints to the Information Loss Paradox and its recent firewall incarnation may lie in understanding more generic geometries than that of Schwarzschild spacetime. Fortunately, for sufficiently large asymptotically flat Reissner-Nordström black holes, the evaporation process can be modeled via a system of coupled linear ordinary differential equations, with charge loss rate governed by Schwinger pair-production process. The same model can be generalized to study the evaporation of AdS Reissner-Nordström black holes with flat horizon. It was recently found that such black holes always evolve towards extremality since charge loss is inefficient. This property is completely opposite to the asymptotically flat case in which the black hole eventually loses its charges and tends towards Schwarzschild limit. We clarify the underlying reason for this different behavior.
Doppler Lidar Wind Value-Added Product
Newsom, R. K.; Sivaraman, C.; Shippert, T. R.; Riihimaki, L. D.
2015-07-01
Wind speed and direction, together with pressure, temperature, and relative humidity, are the most fundamental atmospheric state parameters. Accurate measurement of these parameters is crucial for numerical weather prediction. Vertically resolved wind measurements in the atmospheric boundary layer are particularly important for modeling pollutant and aerosol transport. Raw data from a scanning coherent Doppler lidar system can be processed to generate accurate height-resolved measurements of wind speed and direction in the atmospheric boundary layer.
AdS/QCD, LIight-Front Holography, and the Non-perturbative Running Coupling
Brodsky, Stanley J.; de Teramond, Guy; Deur, Alexandre; /Jefferson Lab
2010-04-29
The combination of Anti-de Sitter space (AdS) methods with light-front (LF) holography provides a remarkably accurate first approximation for the spectra and wavefunctions of meson and baryon light-quark bound states. The resulting bound-state Hamiltonian equation of motion in QCD leads to relativistic light-front wave equations in terms of an invariant impact variable {zeta} which measures the separation of the quark and gluonic constituents within the hadron at equal light-front time. These equations of motion in physical space-time are equivalent to the equations of motion which describe the propagation of spin-J modes in anti-de Sitter (AdS) space. The eigenvalues give the hadronic spectrum, and the eigenmodes represent the probability distributions of the hadronic constituents at a given scale. A positive-sign confining dilaton background modifying AdS space gives a very good account of meson and baryon spectroscopy and form factors. The light-front holographic mapping of this model also leads to a non-perturbative effective coupling {alpha}{sub s}{sup Ads} (Q{sup 2}) which agrees with the effective charge defined by the Bjorken sum rule and lattice simulations. It displays a transition from perturbative to nonperturbative conformal regimes at a momentum scale {approx} 1 GeV. The resulting {beta}-function appears to capture the essential characteristics of the full {beta}-function of QCD, thus giving further support to the application of the gauge/gravity duality to the confining dynamics of strongly coupled QCD.
Value Added Products from Renewable Biofuels
Blum, Paul
2014-07-31
Cellulosic ethanol is an emerging biofuel that will make strong contributions to American domestic energy needs. In the US midwest the standard method for pretreatment of biomass uses hot acid to deconstruct lignocellulose. While other methods work, they are not in common use. Therefore it is necessary to work within this context to achieve process improvements and reductions in biofuel cost. Technology underlying this process could supplement and even replace commodity enzymes with engineered microbes to convert biomass-derived lignocellulose feedstocks into biofuels and valueadded chemicals. The approach that was used here was based on consolidated bioprocessing. Thermoacidophilic microbes belonging to the Domain Archaea were evaluated and modfied to promote deconvolution and saccharification of lignocellulose. Biomass pretreatment (hot acid) was combined with fermentation using an extremely thermoacidophilic microbial platform. The identity and fate of released sugars was controlled using metabolic blocks combined with added biochemical traits where needed. LC/MS analysis supported through the newly established Nebraska Bioenergy Facility provided general support for bioenergy researchers at the University of Nebraska. The primary project strategy was to use microbes that naturally flourish in hot acid (thermoacidophiles) with conventional biomass pretreatment that uses hot acid. The specific objectives were: to screen thermoacidophilic taxa for the ability to deconvolute lignocellulose and depolymerize associated carbohydrates; evaluate and respond to formation of “inhibitors” that arose during incubation of lignocellulose under heated acidic conditions; identify and engineer “sugar flux channeling and catabolic blocks” that redirect metabolic pathways to maximize sugar concentrations; expand the hydrolytic capacity of extremely thermoacidophilic microbes through the addition of deconvolution traits; and establish the Nebraska Bioenergy Facility (NBF
AdS and ds Entropy from String Junctions or the Function of Junction Conjunctions
NASA Astrophysics Data System (ADS)
Silverstein, Eva
Flux compactifications of string theory exhibiting the possibility of discretely tuning the cosmological constant to small values have been constructed. The highly tuned vacua in this discretuum have curvature radii which scale as large powers of the flux quantum numbers, exponential in the number of cycles in the compactiflcation. By the arguments of Susskind/Witten (in the AdS case) and Gibbons/Hawking (in the dS case), we expect correspondingly large entropies associated with these vacua. If they are to provide a dual description of these vacua on their Coulomb branch, branes traded for the flux need to account for this entropy at the appropriate energy scale. In this note, we argue that simple string junctions and webs ending on the branes can account for this large entropy, obtaining a rough estimate for junction entropy that agrees with the existing rough estimates for the spacing of the discretuum. In particular, the brane entropy can account for the (A)dS entropy far away from string scale correspondence limits.
Three dimensional nonlinear magnetic AdS solutions through topological defects
NASA Astrophysics Data System (ADS)
Hendi, S. H.; Panah, B. Eslam; Momennia, M.; Panahiyan, S.
2015-09-01
Inspired by large applications of topological defects in describing different phenomena in physics, and considering the importance of three dimensional solutions in AdS/CFT correspondence, in this paper we obtain magnetic anti-de Sitter solutions of nonlinear electromagnetic fields. We take into account three classes of nonlinear electrodynamic models; first two classes are the well-known Born-Infeld like models including logarithmic and exponential forms and third class is known as the power Maxwell invariant nonlinear electrodynamics. We investigate the effects of these nonlinear sources on three dimensional magnetic solutions. We show that these asymptotical AdS solutions do not have any curvature singularity and horizon. We also generalize the static metric to the case of rotating solutions and find that the value of the electric charge depends on the rotation parameter. Finally, we consider the quadratic Maxwell invariant as a correction of Maxwell theory and we investigate the effects of nonlinearity as a correction. We study the behavior of the deficit angle in presence of these theories of nonlinearity and compare them with each other. We also show that some cases with negative deficit angle exists which are representing objects with different geometrical structure. We also show that in case of the static only magnetic field exists whereas by boosting the metric to rotating one, electric field appears too.
The Sky is the Limit: Free Boundary Conditions in AdS3 Chern-Simons Theory
NASA Astrophysics Data System (ADS)
Apolo, Luis; Sundborg, Bo
We test the effects of new diffeomorphism invariant boundary terms in SL(2,R)×SL(2,R) Chern-Simons theory. The gravitational interpretation corresponds to free AdS3 boundary conditions, without restrictions on the boundary geometry. The boundary theory is the theory of a string in a target AdS3. Its Virasoro conditions can eliminate ghosts. Generalisations to SL(N,R)×SL(N,R) higher spin theories and many other questions are still unexplored.
NASA Astrophysics Data System (ADS)
Buhl-Mortensen, Isak; de Leeuw, Marius; Ipsen, Asger C.; Kristjansen, Charlotte; Wilhelm, Matthias
2017-01-01
We build the framework for performing loop computations in the defect version of N = 4 super Yang-Mills theory which is dual to the probe D5-D3 brane system with background gauge-field flux. In this dCFT, a codimension-one defect separates two regions of space-time with different ranks of the gauge group and three of the scalar fields acquire non-vanishing and space-time-dependent vacuum expectation values. The latter leads to a highly non-trivial mass mixing problem between different colour and flavour components, which we solve using fuzzy-sphere coordinates. Furthermore, the resulting space-time dependence of the theory's Minkowski space propagators is handled by reformulating these as propagators in an effective AdS 4. Subsequently, we initiate the computation of quantum corrections. The one-loop correction to the one-point function of any local gauge-invariant scalar operator is shown to receive contributions from only two Feynman diagrams. We regulate these diagrams using dimensional reduction, finding that one of the two diagrams vanishes, and discuss the procedure for calculating the one-point function of a generic operator from the SU(2) subsector. Finally, we explicitly evaluate the one-loop correction to the one-point function of the BPS vacuum state, finding perfect agreement with an earlier string-theory prediction. This constitutes a highly non-trivial test of the gauge-gravity duality in a situation where both supersymmetry and conformal symmetry are partially broken.
Alliance for aging research AD biomarkers work group: structural MRI.
Jack, Clifford R
2011-12-01
Biomarkers of Alzheimer's disease (AD) are increasingly important. All modern AD therapeutic trials employ AD biomarkers in some capacity. In addition, AD biomarkers are an essential component of recently updated diagnostic criteria for AD from the National Institute on Aging--Alzheimer's Association. Biomarkers serve as proxies for specific pathophysiological features of disease. The 5 most well established AD biomarkers include both brain imaging and cerebrospinal fluid (CSF) measures--cerebrospinal fluid Abeta and tau, amyloid positron emission tomography (PET), fluorodeoxyglucose (FDG) positron emission tomography, and structural magnetic resonance imaging (MRI). This article reviews evidence supporting the position that MRI is a biomarker of neurodegenerative atrophy. Topics covered include methods of extracting quantitative and semiquantitative information from structural MRI; imaging-autopsy correlation; and evidence supporting diagnostic and prognostic value of MRI measures. Finally, the place of MRI in a hypothetical model of temporal ordering of AD biomarkers is reviewed.
Configurational entropy of glueball states
NASA Astrophysics Data System (ADS)
Bernardini, Alex E.; Braga, Nelson R. F.; da Rocha, Roldão
2017-02-01
The configurational entropy of glueball states is calculated using a holographic description. Glueball states are represented by a supergravity dual picture, consisting of a 5-dimensional graviton-dilaton action of a dynamical holographic AdS/QCD model. The configurational entropy is studied as a function of the glueball spin and of the mass, providing information about the stability of the glueball states.
Adding image search capabilities to astronomical archives
NASA Astrophysics Data System (ADS)
Baumann, Peter; Bruggen, Marcus
VO-Paris Data Centre is a common structure to the Observatory of Paris, in charge of develop-ing Virtual Observatory activities. As a partner in Europlanet-IDIS, VO-Paris contributes to defining the future European VO in Planetary Science. There are two aspects in this program: on one hand, VO-Paris is in charge of the IDIS thematic node "Planetary Dynamics and Extra-Terrestrial Matter", which distributes data resources related to this field, including resources developed by other Europlanet Work Packages. On the other hand, OV-Paris is a partner in the Joint Research Activity (JRA4) which designs the VO infrastructure, and is the co-leader of the task "Added Value Services". VO-Paris baseline in Europlanet-IDIS is to remain as compatible as possible with existing VO systems in Astronomy and Solar Physics, ie to use standards and protocols developed in the IVOA context when they suit the need of Planetary Science, and possibly to propose their extensions whenever the existing standards do not address the usual specific questions in Planetary Science. This approach will allow the rapid design of a registry system, and easy use of tools providing basic functions such as data visualization. Concerning the data resources involved, our aim is to set up a core of data services on which the community will accrete new data resources accessible through VO protocols. This initial core is currently expected to include AMDA (CDPP's service in plasma physics), SSODnet (a semi-VO service being developed at OV-Paris), the PSA (ESA's space missions archive), GhoSST (solid samples spectroscopy developed at LPG), and various topical data bases such as a reference data base set up in LESIA to support the Herschel TNO key-program. The OV-Paris IDIS node can be reached at: http://voparis-europlanet.obspm.fr/ The EuroPlaNet RI project is funded by the European Commission under the 7th Framework Program, grant 228319 "Capacities Specific Programme".
Identification of a new plasma biomarker of Alzheimer's disease using metabolomics technology[S
Sato, Yoshiaki; Suzuki, Ikumi; Nakamura, Tatsuji; Bernier, Francois; Aoshima, Ken; Oda, Yoshiya
2012-01-01
We performed unbiased analysis of steroid-related compounds to identify novel Alzheimer's disease (AD) plasma biomarkers using liquid chromatography-atmospheric pressure chemical ionization-mass spectroscopy. The analysis revealed that desmosterol was found to be decreased in AD plasma versus controls. To precisely quantify variations in desmosterol, we established an analytical method to measure desmosterol and cholesterol. Using this LC-based method, we discovered that desmosterol and the desmosterol/cholesterol ratio are significantly decreased in AD. Finally, the validation of this assay using 109 clinical samples confirmed the decrease of desmosterol in AD as well as a change in the desmosterol/cholesterol ratio in AD. Interestingly, we could also observe a difference between mild cognitive impairment and control. In addition, the decrease of desmosterol was somewhat more significant in females. Receiver operating characteristic (ROC) analysis between controls and AD, using plasma desmosterol shows a score of 0.80, indicating a good discrimination power for this marker in the two reference populations and confirms the potential usefulness of measuring plasma desmosterol levels for diagnosing AD. Further analysis showed a significant correlation of plasma desmosterol with Mini-Mental State Examination scores. Although larger sample populations will be needed to confirm this diagnostic marker sensitivity, our studies demonstrate a sensitive and accurate method of detecting plasma desmosterol concentration and suggest that plasma desmosterol could become a powerful new specific biomarker for early and easy AD diagnosis. PMID:22203775
Introduction to the AdS/CFT Correspondence
NASA Astrophysics Data System (ADS)
Nąstase, Horaǧiu
2015-09-01
Preface; Introduction; Part I. Background: 1. Elements of quantum field theory and gauge theory; 2. Basics of general relativity. Anti-de Sitter space; 3. Basics of supersymmetry; 4. Basics of supergravity; 5. Kaluza-Klein dimensional reduction; 6. Black holes and p-branes; 7. String theory actions and spectra; 8. Elements of conformal field theory; 9. D-branes; Part II. Basics of AdS/CFT for N = 4 SYM vs AdS5 × S5: 10. The AdS/CFT correspondence: motivation, definition and spectra; 11. Witten prescription and 3-point correlator calculations; 12. Holography in Lorentzian signature: Poincaré and global; 13. Solitonic objects in AdS/CFT; 14. Quarks and the Wilson loop; 15. Finite temperature and N = 4 SYM plasmas; 16. Scattering processes and gravitational shockwave limit; 17. The pp-wave correspondence; 18. Spin chains; Part III. AdS/CFT Developments and Gauge-Gravity Dualities: 19. Other conformal cases; 20. The 3 dimensional ABJM model vs. AdS4 × CP3; 21. Gravity duals; 22. Holographic renormalization; 23. RG flow between fixed points; 24. Phenomenological gauge-gravity duality I: AdS/QCD; 25. Phenomenological gauge-gravity duality II: AdS/CMT; 26. Gluon scattering: the Alday-Maldacena prescription; 27. Holographic entanglement entropy: the Ryu-Takayanagi prescription.
AD-1 with research pilot Richard E. Gray
NASA Technical Reports Server (NTRS)
1982-01-01
Standing in front of the AD-1 Oblique Wing research aircraft is research pilot Richard E. Gray. Richard E. Gray joined National Aeronautics and Space Administration's Johnson Space Center, Houston, Texas, in November 1978, as an aerospace research pilot. In November 1981, Dick joined the NASA's Ames-Dryden Flight Research Facility, Edwards, California, as a research pilot. Dick was a former Co-op at the NASA Flight Research Center (a previous name of the Ames-Dryden Flight Research Facility), serving as an Operations Engineer. At Ames-Dryden, Dick was a pilot for the F-14 Aileron Rudder Interconnect Program, AD-1 Oblique Wing Research Aircraft, F-8 Digital Fly-By-Wire and Pilot Induced Oscillations investigations. He also flew the F-104, T-37, and the F-15. On November 8, 1982, Gray was fatally injured in a T-37 jet aircraft while making a pilot proficiency flight. Dick graduated with a Bachelors degree in Aeronautical Engineering from San Jose State University in 1969. He joined the U.S. Navy in July 1969, becoming a Naval Aviator in January 1971, when he was assigned to F-4 Phantoms at Naval Air Station (NAS) Miramar, California. In 1972, he flew 48 combat missions in Vietnam in F-4s with VF-111 aboard the USS Coral Sea. After making a second cruise in 1973, Dick was assigned to Air Test and Evaluation Squadron Four (VX-4) at NAS Point Mugu, California, as a project pilot on various operational test and evaluation programs. In November 1978, Dick retired from the Navy and joined NASA's Johnson Space Center. At JSC Gray served as chief project pilot on the WB-57F high-altitude research projects and as the prime television chase pilot in a T-38 for the landing portion of the Space Shuttle orbital flight tests. Dick had over 3,000 hours in more than 30 types of aircraft, an airline transport rating, and 252 carrier arrested landings. He was a member of the Society of Experimental Test Pilots serving on the Board of Directors as Southwest Section Technical Adviser in
ERIC Educational Resources Information Center
Winters, Marcus A.; Cowen, Joshua M.
2013-01-01
Several states have recently adopted or are pursuing policies that deny or revoke tenure from teachers who receive poor evaluation ratings over time based in part on quantitative measures of performance. Using data from the state of Florida, we estimate such value-added measures to consider the future effectiveness and number of teachers who would…
ERIC Educational Resources Information Center
Lazier-Smith, Linda
A pilot study examined trends in the appearance of personal advertisements (individuals seeking dates/mates) in the classified columns of daily newspapers located in state capital cities, as well as newspaper guidelines for the acceptance of personal ads. Daily newspapers in the capital city of each state and some of the larger nationally…
Nonvacuum AdS cosmology and comments on gauge theory correlator
NASA Astrophysics Data System (ADS)
Chatterjee, Soumyabrata; Chowdhury, Sudipto Paul; Mukherji, Sudipta; Srivastava, Yogesh K.
2017-02-01
Several time dependent backgrounds, with perfect fluid matter, can be used to construct solutions of Einstein equations in the presence of a negative cosmological constant along with some matter sources. In this work we focus on the non-vacuum Kasner-AdS geometry and its solitonic generalization. To characterize these space-times, we provide ways to embed them in higher dimensional flat space-times. General space-like geodesics are then studied and used to compute the two point boundary correlators within the geodesic approximation.
Adding to the Mercury Speciation Toolbox
NASA Astrophysics Data System (ADS)
Fitts, J. P.; Northrup, P. A.; Chidambaram, D.; Kalb, P. D.
2007-12-01
Mercury was used to separate lithium-6 isotope for weapons production at the Y-12 Plant in Oak Ridge, TN in the 1950s and 1960s. A large portion of the waste Hg entered the environment and continues to move throughout the sub-surface and surface waters in the area. Environmental management of Hg contamination within this complex hydrologic system, where Hg speciation and the mobile fraction have been found to vary widely, will require ongoing characterization and predictive modeling of Hg speciation. State-of-the-art spectroscopic tools that can directly probe Hg speciation in preserved aqueous and sediment samples with greater sensitivity, however, are required to determine rates and mechanisms of biogeochemical reactions. We will present the first results demonstrating the use of x-ray absorption spectroscopy (XAS) at the Hg M5 edge (2295 eV) to fingerprint Hg species. Heavy-metal M5 absorption edges can have very sharp features due to local electron transitions, and therefore, we are developing this edge as a tool for quantitative measurement of Hg species. In addition, sulfur speciation using the sulfur K absorption edge, which is at a similar energy (2472 eV), can be measured in the same scan as the Hg M5 edge. Potentially important organic and inorganic sulfur species (sulfide, disulfide, elemental sulfur, sulfite and sulfate) are readily differentiated, and thereby, provides an independent method for monitoring the redox state of the system along with changes in S-Hg bonding. We will also present x-ray microprobe 2-D concentration maps of Hg and other elements at the grain and pore scales to identify its microscopic distribution and chemical associations. When used in combination with established sequential extraction and direct spectroscopic methods, the addition of XAS at the Hg M5 edge should provide a significant advancement in the determination of Hg speciation in complex biogeochemical environments.
Holographic thermalization and generalized Vaidya-AdS solutions in massive gravity
NASA Astrophysics Data System (ADS)
Hu, Ya-Peng; Zeng, Xiao-Xiong; Zhang, Hai-Qing
2017-02-01
We investigate the effect of massive graviton on the holographic thermalization process. Before doing this, we first find out the generalized Vaidya-AdS solutions in the de Rham-Gabadadze-Tolley (dRGT) massive gravity by directly solving the gravitational equations. Then, we study the thermodynamics of these Vaidya-AdS solutions by using the Misner-Sharp energy and unified first law, which also shows that the massive gravity is in a thermodynamic equilibrium state. Moreover, we adopt the two-point correlation function at equal time to explore the thermalization process in the dual field theory, and to see how the graviton mass parameter affects this process from the viewpoint of AdS/CFT correspondence. Our results show that the graviton mass parameter will increase the holographic thermalization process.
Analytic self-gravitating Skyrmions, cosmological bounces and AdS wormholes
NASA Astrophysics Data System (ADS)
Ayón-Beato, Eloy; Canfora, Fabrizio; Zanelli, Jorge
2016-01-01
We present a self-gravitating, analytic and globally regular Skyrmion solution of the Einstein-Skyrme system with winding number w = ± 1, in presence of a cosmological constant. The static spacetime metric is the direct product R ×S3 and the Skyrmion is the self-gravitating generalization of the static hedgehog solution of Manton and Ruback with unit topological charge. This solution can be promoted to a dynamical one in which the spacetime is a cosmology of the Bianchi type-IX with time-dependent scale and squashing coefficients. Remarkably, the Skyrme equations are still identically satisfied for all values of these parameters. Thus, the complete set of field equations for the Einstein-Skyrme-Λ system in the topological sector reduces to a pair of coupled, autonomous, nonlinear differential equations for the scale factor and a squashing coefficient. These equations admit analytic bouncing cosmological solutions in which the universe contracts to a minimum non-vanishing size, and then expands. A non-trivial byproduct of this solution is that a minor modification of the construction gives rise to a family of stationary, regular configurations in General Relativity with negative cosmological constant supported by an SU (2) nonlinear sigma model. These solutions represent traversable AdS wormholes with NUT parameter in which the only "exotic matter" required for their construction is a negative cosmological constant.
Symplectic and Killing symmetries of AdS3 gravity: holographic vs boundary gravitons
NASA Astrophysics Data System (ADS)
Compère, G.; Mao, P.; Seraj, A.; Sheikh-Jabbari, M. M.
2016-01-01
The set of solutions to the AdS3 Einstein gravity with Brown-Henneaux boundary conditions is known to be a family of metrics labeled by two arbitrary periodic functions, respectively left and right-moving. It turns out that there exists an appropriate presymplectic form which vanishes on-shell. This promotes this set of metrics to a phase space in which the Brown-Henneaux asymptotic symmetries become symplectic symmetries in the bulk of spacetime. Moreover, any element in the phase space admits two global Killing vectors. We show that the conserved charges associated with these Killing vectors commute with the Virasoro symplectic symmetry algebra, extending the Virasoro symmetry algebra with two U(1) generators. We discuss that any element in the phase space falls into the coadjoint orbits of the Virasoro algebras and that each orbit is labeled by the U(1) Killing charges. Upon setting the right-moving function to zero and restricting the choice of orbits, one can take a near-horizon decoupling limit which preserves a chiral half of the symplectic symmetries. Here we show two distinct but equivalent ways in which the chiral Virasoro symplectic symmetries in the near-horizon geometry can be obtained as a limit of the bulk symplectic symmetries.