Science.gov

Sample records for adaptive processes including

  1. Adaptive Signal Processing Testbed

    NASA Astrophysics Data System (ADS)

    Parliament, Hugh A.

    1991-09-01

    The design and implementation of a system for the acquisition, processing, and analysis of signal data is described. The initial application for the system is the development and analysis of algorithms for excision of interfering tones from direct sequence spread spectrum communication systems. The system is called the Adaptive Signal Processing Testbed (ASPT) and is an integrated hardware and software system built around the TMS320C30 chip. The hardware consists of a radio frequency data source, digital receiver, and an adaptive signal processor implemented on a Sun workstation. The software components of the ASPT consists of a number of packages including the Sun driver package; UNIX programs that support software development on the TMS320C30 boards; UNIX programs that provide the control, user interaction, and display capabilities for the data acquisition, processing, and analysis components of the ASPT; and programs that perform the ASPT functions including data acquisition, despreading, and adaptive filtering. The performance of the ASPT system is evaluated by comparing actual data rates against their desired values. A number of system limitations are identified and recommendations are made for improvements.

  2. MITRE Adaptive Processing Capability

    DTIC Science & Technology

    1994-06-01

    gathering, Funded Research and Development transfer, processing , and interpretation of Center (FFRDC) under the primary data are provided. A strong state-of...1988: Unisys Reston Technology Center, Reston, VA Dr. Bronez was a Member of the Technical Staff. He performed research on signal processing and... processing , mathematical research , and sensor array processing . He was Project Leader and Principal Investigator for projects in adaptive beamforming

  3. Experimental adaptive process tomography

    NASA Astrophysics Data System (ADS)

    Pogorelov, I. A.; Struchalin, G. I.; Straupe, S. S.; Radchenko, I. V.; Kravtsov, K. S.; Kulik, S. P.

    2017-01-01

    Adaptive measurements were recently shown to significantly improve the performance of quantum state tomography. Utilizing information about the system for the online choice of optimal measurements allows one to reach the ultimate bounds of precision for state reconstruction. In this article we generalize an adaptive Bayesian approach to the case of process tomography and experimentally show its superiority in the task of learning unknown quantum operations. Our experiments with photonic polarization qubits cover all types of single-qubit channels. We also discuss instrumental errors and the criteria for evaluation of the ultimate achievable precision in an experiment. It turns out that adaptive tomography provides a lower noise floor in the presence of strong technical noise.

  4. Adaptive passive fathometer processing.

    PubMed

    Siderius, Martin; Song, Heechun; Gerstoft, Peter; Hodgkiss, William S; Hursky, Paul; Harrison, Chris

    2010-04-01

    Recently, a technique has been developed to image seabed layers using the ocean ambient noise field as the sound source. This so called passive fathometer technique exploits the naturally occurring acoustic sounds generated on the sea-surface, primarily from breaking waves. The method is based on the cross-correlation of noise from the ocean surface with its echo from the seabed, which recovers travel times to significant seabed reflectors. To limit averaging time and make this practical, beamforming is used with a vertical array of hydrophones to reduce interference from horizontally propagating noise. The initial development used conventional beamforming, but significant improvements have been realized using adaptive techniques. In this paper, adaptive methods for this process are described and applied to several data sets to demonstrate improvements possible as compared to conventional processing.

  5. Adaptive processing for LANDSAT data

    NASA Technical Reports Server (NTRS)

    Crane, R. B.; Reyer, J. F.

    1975-01-01

    Analytical and test results on the use of adaptive processing on LANDSAT data are presented. The Kalman filter was used as a framework to contain different adapting techniques. When LANDSAT MSS data were used all of the modifications made to the Kalman filter performed the functions for which they were designed. It was found that adaptive processing could provide compensation for incorrect signature means, within limits. However, if the data were such that poor classification accuracy would be obtained when the correct means were used, then adaptive processing would not improve the accuracy and might well lower it even further.

  6. Catalyst regeneration process including metal contaminants removal

    DOEpatents

    Ganguli, Partha S.

    1984-01-01

    Spent catalysts removed from a catalytic hydrogenation process for hydrocarbon feedstocks, and containing undesired metals contaminants deposits, are regenerated. Following solvent washing to remove process oils, the catalyst is treated either with chemicals which form sulfate or oxysulfate compounds with the metals contaminants, or with acids which remove the metal contaminants, such as 5-50 W % sulfuric acid in aqueous solution and 0-10 W % ammonium ion solutions to substantially remove the metals deposits. The acid treating occurs within the temperature range of 60.degree.-250.degree. F. for 5-120 minutes at substantially atmospheric pressure. Carbon deposits are removed from the treated catalyst by carbon burnoff at 800.degree.-900.degree. F. temperature, using 1-6 V % oxygen in an inert gas mixture, after which the regenerated catalyst can be effectively reused in the catalytic process.

  7. Extending Newtonian Dynamics to Include Stochastic Processes

    NASA Technical Reports Server (NTRS)

    Zak, Michail

    2009-01-01

    A paper presents further results of continuing research reported in several previous NASA Tech Briefs articles, the two most recent being Stochastic Representations of Chaos Using Terminal Attractors (NPO-41519), [Vol. 30, No. 5 (May 2006), page 57] and Physical Principle for Generation of Randomness (NPO-43822) [Vol. 33, No. 5 (May 2009), page 56]. This research focuses upon a mathematical formalism for describing post-instability motions of a dynamical system characterized by exponential divergences of trajectories leading to chaos (including turbulence as a form of chaos). The formalism involves fictitious control forces that couple the equations of motion of the system with a Liouville equation that describes the evolution of the probability density of errors in initial conditions. These stabilizing forces create a powerful terminal attractor in probability space that corresponds to occurrence of a target trajectory with probability one. The effect in configuration space (ordinary three-dimensional space as commonly perceived) is to suppress exponential divergences of neighboring trajectories without affecting the target trajectory. As a result, the post-instability motion is represented by a set of functions describing the evolution of such statistical quantities as expectations and higher moments, and this representation is stable.

  8. A Novel Approach for Adaptive Signal Processing

    NASA Technical Reports Server (NTRS)

    Chen, Ya-Chin; Juang, Jer-Nan

    1998-01-01

    Adaptive linear predictors have been used extensively in practice in a wide variety of forms. In the main, their theoretical development is based upon the assumption of stationarity of the signals involved, particularly with respect to the second order statistics. On this basis, the well-known normal equations can be formulated. If high- order statistical stationarity is assumed, then the equivalent normal equations involve high-order signal moments. In either case, the cross moments (second or higher) are needed. This renders the adaptive prediction procedure non-blind. A novel procedure for blind adaptive prediction has been proposed and considerable implementation has been made in our contributions in the past year. The approach is based upon a suitable interpretation of blind equalization methods that satisfy the constant modulus property and offers significant deviations from the standard prediction methods. These blind adaptive algorithms are derived by formulating Lagrange equivalents from mechanisms of constrained optimization. In this report, other new update algorithms are derived from the fundamental concepts of advanced system identification to carry out the proposed blind adaptive prediction. The results of the work can be extended to a number of control-related problems, such as disturbance identification. The basic principles are outlined in this report and differences from other existing methods are discussed. The applications implemented are speech processing, such as coding and synthesis. Simulations are included to verify the novel modelling method.

  9. Acousto-Optic Adaptive Processing (AOAP).

    DTIC Science & Technology

    1983-12-01

    I ~.sls Phe Report December 1963 •- ACOUSTO - OPTIC ADAPTIVE <PROCESSING (AOAP) General Electric Company W. A. Penn, D. R. Morgan, A. Aridgides and M. L...numnber) Optical signal processing Acousto - optical modulators Adaptive signal processing - Adaptive sidelobe cancellation 20. ABSTRACT (Contnue an...required operations of multiplication and time delay are provided by acousto - optical (AO) delay lines. The required time integraticO is provided by

  10. Optical Profilometers Using Adaptive Signal Processing

    NASA Technical Reports Server (NTRS)

    Hall, Gregory A.; Youngquist, Robert; Mikhael, Wasfy

    2006-01-01

    A method of adaptive signal processing has been proposed as the basis of a new generation of interferometric optical profilometers for measuring surfaces. The proposed profilometers would be portable, hand-held units. Sizes could be thus reduced because the adaptive-signal-processing method would make it possible to substitute lower-power coherent light sources (e.g., laser diodes) for white light sources and would eliminate the need for most of the optical components of current white-light profilometers. The adaptive-signal-processing method would make it possible to attain scanning ranges of the order of decimeters in the proposed profilometers.

  11. Adaptive Process Control in Rubber Industry.

    PubMed

    Brause, Rüdiger W; Pietruschka, Ulf

    1998-01-01

    This paper describes the problems and an adaptive solution for process control in rubber industry. We show that the human and economical benefits of an adaptive solution for the approximation of process parameters are very attractive. The modeling of the industrial problem is done by the means of artificial neural networks. For the example of the extrusion of a rubber profile in tire production our method shows good resuits even using only a few training samples.

  12. Neural Adaptation Effects in Conceptual Processing.

    PubMed

    Marino, Barbara F M; Borghi, Anna M; Gemmi, Luca; Cacciari, Cristina; Riggio, Lucia

    2015-07-31

    We investigated the conceptual processing of nouns referring to objects characterized by a highly typical color and orientation. We used a go/no-go task in which we asked participants to categorize each noun as referring or not to natural entities (e.g., animals) after a selective adaptation of color-edge neurons in the posterior LV4 region of the visual cortex was induced by means of a McCollough effect procedure. This manipulation affected categorization: the green-vertical adaptation led to slower responses than the green-horizontal adaptation, regardless of the specific color and orientation of the to-be-categorized noun. This result suggests that the conceptual processing of natural entities may entail the activation of modality-specific neural channels with weights proportional to the reliability of the signals produced by these channels during actual perception. This finding is discussed with reference to the debate about the grounded cognition view.

  13. Neural Adaptation Effects in Conceptual Processing

    PubMed Central

    Marino, Barbara F. M.; Borghi, Anna M.; Gemmi, Luca; Cacciari, Cristina; Riggio, Lucia

    2015-01-01

    We investigated the conceptual processing of nouns referring to objects characterized by a highly typical color and orientation. We used a go/no-go task in which we asked participants to categorize each noun as referring or not to natural entities (e.g., animals) after a selective adaptation of color-edge neurons in the posterior LV4 region of the visual cortex was induced by means of a McCollough effect procedure. This manipulation affected categorization: the green-vertical adaptation led to slower responses than the green-horizontal adaptation, regardless of the specific color and orientation of the to-be-categorized noun. This result suggests that the conceptual processing of natural entities may entail the activation of modality-specific neural channels with weights proportional to the reliability of the signals produced by these channels during actual perception. This finding is discussed with reference to the debate about the grounded cognition view. PMID:26264031

  14. Adaptive schemes for incomplete quantum process tomography

    SciTech Connect

    Teo, Yong Siah; Englert, Berthold-Georg; Rehacek, Jaroslav; Hradil, Zdenek

    2011-12-15

    We propose an iterative algorithm for incomplete quantum process tomography with the help of quantum state estimation. The algorithm, which is based on the combined principles of maximum likelihood and maximum entropy, yields a unique estimator for an unknown quantum process when one has less than a complete set of linearly independent measurement data to specify the quantum process uniquely. We apply this iterative algorithm adaptively in various situations and so optimize the amount of resources required to estimate a quantum process with incomplete data.

  15. Photorefractive processing for large adaptive phased arrays

    NASA Astrophysics Data System (ADS)

    Weverka, Robert T.; Wagner, Kelvin; Sarto, Anthony

    1996-03-01

    An adaptive null-steering phased-array optical processor that utilizes a photorefractive crystal to time integrate the adaptive weights and null out correlated jammers is described. This is a beam-steering processor in which the temporal waveform of the desired signal is known but the look direction is not. The processor computes the angle(s) of arrival of the desired signal and steers the array to look in that direction while rotating the nulls of the antenna pattern toward any narrow-band jammers that may be present. We have experimentally demonstrated a simplified version of this adaptive phased-array-radar processor that nulls out the narrow-band jammers by using feedback-correlation detection. In this processor it is assumed that we know a priori only that the signal is broadband and the jammers are narrow band. These are examples of a class of optical processors that use the angular selectivity of volume holograms to form the nulls and look directions in an adaptive phased-array-radar pattern and thereby to harness the computational abilities of three-dimensional parallelism in the volume of photorefractive crystals. The development of this processing in volume holographic system has led to a new algorithm for phased-array-radar processing that uses fewer tapped-delay lines than does the classic time-domain beam former. The optical implementation of the new algorithm has the further advantage of utilization of a single photorefractive crystal to implement as many as a million adaptive weights, allowing the radar system to scale to large size with no increase in processing hardware.

  16. Using assistive technology adaptations to include students with learning disabilities in cooperative learning activities.

    PubMed

    Bryant, D P; Bryant, B R

    1998-01-01

    Cooperative learning (CL) is a common instructional arrangement that is used by classroom teachers to foster academic achievement and social acceptance of students with and without learning disabilities. Cooperative learning is appealing to classroom teachers because it can provide an opportunity for more instruction and feedback by peers than can be provided by teachers to individual students who require extra assistance. Recent studies suggest that students with LD may need adaptations during cooperative learning activities. The use of assistive technology adaptations may be necessary to help some students with LD compensate for their specific learning difficulties so that they can engage more readily in cooperative learning activities. A process for integrating technology adaptations into cooperative learning activities is discussed in terms of three components: selecting adaptations, monitoring the use of the adaptations during cooperative learning activities, and evaluating the adaptations' effectiveness. The article concludes with comments regarding barriers to and support systems for technology integration, technology and effective instructional practices, and the need to consider technology adaptations for students who have learning disabilities.

  17. Contrast Adaptation Implies Two Spatiotemporal Channels but Three Adapting Processes

    ERIC Educational Resources Information Center

    Langley, Keith; Bex, Peter J.

    2007-01-01

    The contrast gain control model of adaptation predicts that the effects of contrast adaptation correlate with contrast sensitivity. This article reports that the effects of high contrast spatiotemporal adaptors are maximum when adapting around 19 Hz, which is a factor of two or more greater than the peak in contrast sensitivity. To explain the…

  18. Motor adaptation as a process of reoptimization.

    PubMed

    Izawa, Jun; Rane, Tushar; Donchin, Opher; Shadmehr, Reza

    2008-03-12

    Adaptation is sometimes viewed as a process in which the nervous system learns to predict and cancel effects of a novel environment, returning movements to near baseline (unperturbed) conditions. An alternate view is that cancellation is not the goal of adaptation. Rather, the goal is to maximize performance in that environment. If performance criteria are well defined, theory allows one to predict the reoptimized trajectory. For example, if velocity-dependent forces perturb the hand perpendicular to the direction of a reaching movement, the best reach plan is not a straight line but a curved path that appears to overcompensate for the forces. If this environment is stochastic (changing from trial to trial), the reoptimized plan should take into account this uncertainty, removing the overcompensation. If the stochastic environment is zero-mean, peak velocities should increase to allow for more time to approach the target. Finally, if one is reaching through a via-point, the optimum plan in a zero-mean deterministic environment is a smooth movement but in a zero-mean stochastic environment is a segmented movement. We observed all of these tendencies in how people adapt to novel environments. Therefore, motor control in a novel environment is not a process of perturbation cancellation. Rather, the process resembles reoptimization: through practice in the novel environment, we learn internal models that predict sensory consequences of motor commands. Through reward-based optimization, we use the internal model to search for a better movement plan to minimize implicit motor costs and maximize rewards.

  19. Coping and adaptation process during puerperium

    PubMed Central

    Muñoz de Rodríguez, Lucy; Ruiz de Cárdenas, Carmen Helena

    2012-01-01

    Introduction: The puerperium is a stage that produces changes and adaptations in women, couples and family. Effective coping, during this stage, depends on the relationship between the demands of stressful or difficult situations and the recourses that the puerperal individual has. Roy (2004), in her Middle Range Theory about the Coping and Adaptation Processing, defines Coping as the ''behavioral and cognitive efforts that a person makes to meet the environment demands''. For the puerperal individual, the correct coping is necessary to maintain her physical and mental well being, especially against situations that can be stressful like breastfeeding and return to work. According to Lazarus and Folkman (1986), a resource for coping is to have someone who receives emotional support, informative and / or tangible. Objective: To review the issue of women coping and adaptation during the puerperium stage and the strategies that enhance this adaptation. Methods: search and selection of database articles: Cochrane, Medline, Ovid, ProQuest, Scielo, and Blackwell Synergy. Other sources: unpublished documents by Roy, published books on Roy´s Model, Websites from of international health organizations. Results: the need to recognize the puerperium as a stage that requires comprehensive care is evident, where nurses must be protagonist with the care offered to women and their families, considering the specific demands of this situation and recourses that promote effective coping and the family, education and health services. PMID:24893059

  20. True-Time-Delay Adaptive Array Processing Using Photorefractive Crystals

    NASA Astrophysics Data System (ADS)

    Kriehn, G. R.; Wagner, K.

    Radio frequency (RF) signal processing has proven to be a fertile application area when using photorefractive-based, optical processing techniques. This is due to a photorefractive material's capability to record gratings and diffract off these gratings with optically modulated beams that contain a wide RF bandwidth, and include applications such as the bias-free time-integrating correlator [1], adaptive signal processing, and jammer excision, [2, 3, 4]. Photorefractive processing of signals from RF antenna arrays is especially appropriate because of the massive parallelism that is readily achievable in a photorefractive crystal (in which many resolvable beams can be incident on a single crystal simultaneously—each coming from an optical modulator driven by a separate RF antenna element), and because a number of approaches for adaptive array processing using photorefractive crystals have been successfully investigated [5, 6]. In these types of applications, the adaptive weight coefficients are represented by the amplitude and phase of the holographic gratings, and many millions of such adaptive weights can be multiplexed within the volume of a photorefractive crystal. RF modulated optical signals from each array element are diffracted from the adaptively recorded photorefractive gratings (which can be multiplexed either angularly or spatially), and are then coherently combined with the appropriate amplitude weights and phase shifts to effectively steer the angular receptivity pattern of the antenna array toward the desired arriving signal. Likewise, the antenna nulls can also be rotated toward unwanted narrowband jammers for extinction, thereby optimizing the signal-to-interference-plus-noise ratio.

  1. A framework for automated contour quality assurance in radiation therapy including adaptive techniques

    NASA Astrophysics Data System (ADS)

    Altman, M. B.; Kavanaugh, J. A.; Wooten, H. O.; Green, O. L.; DeWees, T. A.; Gay, H.; Thorstad, W. L.; Li, H.; Mutic, S.

    2015-07-01

    Contouring of targets and normal tissues is one of the largest sources of variability in radiation therapy treatment plans. Contours thus require a time intensive and error-prone quality assurance (QA) evaluation, limitations which also impair the facilitation of adaptive radiotherapy (ART). Here, an automated system for contour QA is developed using historical data (the ‘knowledge base’). A pilot study was performed with a knowledge base derived from 9 contours each from 29 head-and-neck treatment plans. Size, shape, relative position, and other clinically-relevant metrics and heuristically derived rules are determined. Metrics are extracted from input patient data and compared against rules determined from the knowledge base; a computer-learning component allows metrics to evolve with more input data, including patient specific data for ART. Nine additional plans containing 42 unique contouring errors were analyzed. 40/42 errors were detected as were 9 false positives. The results of this study imply knowledge-based contour QA could potentially enhance the safety and effectiveness of RT treatment plans as well as increase the efficiency of the treatment planning process, reducing labor and the cost of therapy for patients.

  2. Adaptation.

    PubMed

    Broom, Donald M

    2006-01-01

    The term adaptation is used in biology in three different ways. It may refer to changes which occur at the cell and organ level, or at the individual level, or at the level of gene action and evolutionary processes. Adaptation by cells, especially nerve cells helps in: communication within the body, the distinguishing of stimuli, the avoidance of overload and the conservation of energy. The time course and complexity of these mechanisms varies. Adaptive characters of organisms, including adaptive behaviours, increase fitness so this adaptation is evolutionary. The major part of this paper concerns adaptation by individuals and its relationships to welfare. In complex animals, feed forward control is widely used. Individuals predict problems and adapt by acting before the environmental effect is substantial. Much of adaptation involves brain control and animals have a set of needs, located in the brain and acting largely via motivational mechanisms, to regulate life. Needs may be for resources but are also for actions and stimuli which are part of the mechanism which has evolved to obtain the resources. Hence pigs do not just need food but need to be able to carry out actions like rooting in earth or manipulating materials which are part of foraging behaviour. The welfare of an individual is its state as regards its attempts to cope with its environment. This state includes various adaptive mechanisms including feelings and those which cope with disease. The part of welfare which is concerned with coping with pathology is health. Disease, which implies some significant effect of pathology, always results in poor welfare. Welfare varies over a range from very good, when adaptation is effective and there are feelings of pleasure or contentment, to very poor. A key point concerning the concept of individual adaptation in relation to welfare is that welfare may be good or poor while adaptation is occurring. Some adaptation is very easy and energetically cheap and

  3. Nation-building policies in Timor-Leste: disaster risk reduction, including climate change adaptation.

    PubMed

    Mercer, Jessica; Kelman, Ilan; do Rosario, Francisco; de Deus de Jesus Lima, Abilio; da Silva, Augusto; Beloff, Anna-Maija; McClean, Alex

    2014-10-01

    Few studies have explored the relationships between nation-building, disaster risk reduction and climate change adaptation. Focusing on small island developing states, this paper examines nation-building in Timor-Leste, a small island developing state that recently achieved independence. Nation-building in Timor-Leste is explored in the context of disaster risk reduction, which necessarily includes climate change adaptation. The study presents a synopsis of Timor-Leste's history and its nation-building efforts as well as an overview of the state of knowledge of disaster risk reduction including climate change adaptation. It also offers an analysis of significant gaps and challenges in terms of vertical and horizontal governance, large donor presence, data availability and the integration of disaster risk reduction and climate change adaptation for nation-building in Timor-Leste. Relevant and applicable lessons are provided from other small island developing states to assist Timor-Leste in identifying its own trajectory out of underdevelopment while it builds on existing strengths.

  4. Landsat Ecosystem Disturbance Adaptive Processing System (LEDAPS)

    NASA Technical Reports Server (NTRS)

    Masek, Jeffrey G.

    2006-01-01

    The Landsat Ecosystem Disturbance Adaptive Processing System (LEDAPS) project is creating a record of forest disturbance and regrowth for North America from the Landsat satellite record, in support of the carbon modeling activities. LEDAPS relies on the decadal Landsat GeoCover data set supplemented by dense image time series for selected locations. Imagery is first atmospherically corrected to surface reflectance, and then change detection algorithms are used to extract disturbance area, type, and frequency. Reuse of the MODIS Land processing system (MODAPS) architecture allows rapid throughput of over 2200 MSS, TM, and ETM+ scenes. Initial ("Beta") surface reflectance products are currently available for testing, and initial continental disturbance products will be available by the middle of 2006.

  5. Adaptive and compressive matched field processing.

    PubMed

    Gemba, Kay L; Hodgkiss, William S; Gerstoft, Peter

    2017-01-01

    Matched field processing is a generalized beamforming method that matches received array data to a dictionary of replica vectors in order to locate one or more sources. Its solution set is sparse since there are considerably fewer sources than replicas. Using compressive sensing (CS) implemented using basis pursuit, the matched field problem is reformulated as an underdetermined, convex optimization problem. CS estimates the unknown source amplitudes using the replica dictionary to best explain the data, subject to a row-sparsity constraint. This constraint selects the best matching replicas within the dictionary when using multiple observations and/or frequencies. For a single source, theory and simulations show that the performance of CS and the Bartlett processor are equivalent for any number of snapshots. Contrary to most adaptive processors, CS also can accommodate coherent sources. For a single and multiple incoherent sources, simulations indicate that CS offers modest localization performance improvement over the adaptive white noise constraint processor. SWellEx-96 experiment data results show comparable performance for both processors when localizing a weaker source in the presence of a stronger source. Moreover, CS often displays less ambiguity, demonstrating it is robust to data-replica mismatch.

  6. Adaptive Noise Suppression Using Digital Signal Processing

    NASA Technical Reports Server (NTRS)

    Kozel, David; Nelson, Richard

    1996-01-01

    A signal to noise ratio dependent adaptive spectral subtraction algorithm is developed to eliminate noise from noise corrupted speech signals. The algorithm determines the signal to noise ratio and adjusts the spectral subtraction proportion appropriately. After spectra subtraction low amplitude signals are squelched. A single microphone is used to obtain both eh noise corrupted speech and the average noise estimate. This is done by determining if the frame of data being sampled is a voiced or unvoiced frame. During unvoice frames an estimate of the noise is obtained. A running average of the noise is used to approximate the expected value of the noise. Applications include the emergency egress vehicle and the crawler transporter.

  7. The Urban Adaptation and Adaptation Process of Urban Migrant Children: A Qualitative Study

    ERIC Educational Resources Information Center

    Liu, Yang; Fang, Xiaoyi; Cai, Rong; Wu, Yang; Zhang, Yaofang

    2009-01-01

    This article employs qualitative research methods to explore the urban adaptation and adaptation processes of Chinese migrant children. Through twenty-one in-depth interviews with migrant children, the researchers discovered: The participant migrant children showed a fairly high level of adaptation to the city; their process of urban adaptation…

  8. Space-time adaptive processing with sum and multiple difference beams for airborne radars

    NASA Astrophysics Data System (ADS)

    Maher, John E.; Zhang, Yuhong; Wang, Hong

    1999-07-01

    This paper describes some new results on a signal processing approach for airborne surveillance radars. This is a space- time adaptive processing technique that simultaneously processes temporal data from sum and difference ((Sigma) (Delta) ) beams to suppress clutter returns. The approach also includes employing spatial adaptive pre- suppression to suppress wideband noise jammers in a two- stage processor.

  9. Distributed relaxation processes in sensory adaptation.

    PubMed

    Thorson, J; Biederman-Thorson, M

    1974-01-18

    Dynamic description of most receptors, even in their near-linear ranges, has not led to understanding of the underlying physical events-in many instances because their curious transfer functions are not found in the usual repertoire of integral-order control-system analysis. We have described some methods, borrowed from other fields, which allow one to map any linear frequency response onto a putative weighting over an ensemble of simpler relaxation processes. One can then ask whether the resultant weighting of such processes suggests a corresponding plausible distribution of values for an appropriate physical variable within the sensory transducer. To illustrate this approach, we have chosen the fractional-order low-frequency response of Limulus lateral-eye photoreceptors. We show first that the current "adapting-bump" hypothesis for the generator potential can be formulated in terms of local first-order relaxation processes in which local light flux, the cross section of rhodopsin for photon capture, and restoration rate of local conductance-changing capability play specific roles. A representative spatial distribution for one of these parameters, which just accounts for the low-frequency response of the receptor, is then derived and its relation to cellular properties and recent experiments is examined. Finally, we show that for such a system, nonintegral-order dynamics are equivalent to nonhyperbolic statics, and that the efficacy distribution derived to account for the small-signal dynamics in fact predicts several decades of near-logarithmic response in the steady state. Encouraged by the result that one plausible proposal can account approximately for both the low-frequency dynamics (the transfer function s(k)) and the range-compressing statics (the Weber-Fechner relationship) measured in this photoreceptor, we have described some formally similar applications of these distributed effects to the vertebrate retina and to analogous properties of

  10. Process, including membrane separation, for separating hydrogen from hydrocarbons

    DOEpatents

    Baker, Richard W.; Lokhandwala, Kaaeid A.; He, Zhenjie; Pinnau, Ingo

    2001-01-01

    Processes for providing improved methane removal and hydrogen reuse in reactors, particularly in refineries and petrochemical plants. The improved methane removal is achieved by selective purging, by passing gases in the reactor recycle loop across membranes selective in favor of methane over hydrogen, and capable of exhibiting a methane/hydrogen selectivity of at least about 2.5 under the process conditions.

  11. Articles which include chevron film cooling holes, and related processes

    SciTech Connect

    Bunker, Ronald Scott; Lacy, Benjamin Paul

    2014-12-09

    An article is described, including an inner surface which can be exposed to a first fluid; an inlet; and an outer surface spaced from the inner surface, which can be exposed to a hotter second fluid. The article further includes at least one row or other pattern of passage holes. Each passage hole includes an inlet bore extending through the substrate from the inlet at the inner surface to a passage hole-exit proximate to the outer surface, with the inlet bore terminating in a chevron outlet adjacent the hole-exit. The chevron outlet includes a pair of wing troughs having a common surface region between them. The common surface region includes a valley which is adjacent the hole-exit; and a plateau adjacent the valley. The article can be an airfoil. Related methods for preparing the passage holes are also described.

  12. Adaptive, predictive controller for optimal process control

    SciTech Connect

    Brown, S.K.; Baum, C.C.; Bowling, P.S.; Buescher, K.L.; Hanagandi, V.M.; Hinde, R.F. Jr.; Jones, R.D.; Parkinson, W.J.

    1995-12-01

    One can derive a model for use in a Model Predictive Controller (MPC) from first principles or from experimental data. Until recently, both methods failed for all but the simplest processes. First principles are almost always incomplete and fitting to experimental data fails for dimensions greater than one as well as for non-linear cases. Several authors have suggested the use of a neural network to fit the experimental data to a multi-dimensional and/or non-linear model. Most networks, however, use simple sigmoid functions and backpropagation for fitting. Training of these networks generally requires large amounts of data and, consequently, very long training times. In 1993 we reported on the tuning and optimization of a negative ion source using a special neural network[2]. One of the properties of this network (CNLSnet), a modified radial basis function network, is that it is able to fit data with few basis functions. Another is that its training is linear resulting in guaranteed convergence and rapid training. We found the training to be rapid enough to support real-time control. This work has been extended to incorporate this network into an MPC using the model built by the network for predictive control. This controller has shown some remarkable capabilities in such non-linear applications as continuous stirred exothermic tank reactors and high-purity fractional distillation columns[3]. The controller is able not only to build an appropriate model from operating data but also to thin the network continuously so that the model adapts to changing plant conditions. The controller is discussed as well as its possible use in various of the difficult control problems that face this community.

  13. Adaptive data assimilation including the effect of spatial variations in observation error

    NASA Astrophysics Data System (ADS)

    Frehlich, Rod

    2006-04-01

    An optimal adaptive data assimilation algorithm is derived using the maximum likelihood method based on a conditional Gaussian probability density function for the first-guess and direct observations of the state variables but including local estimates of the observation and first-guess error statistics. An interpolation of the first-guess field to the observation coordinates is not required under the assumption of locally homogeneous statistics for the random atmosphere. However, the definition of observation error requires a definition of model 'truth' which is defined as a spatial average of the continuous random atmospheric variables. Then the total observation error consists of two independent components: an instrument error and an observation sampling error defined by the spatial average of the observation and the statistics of the local turbulence. Estimates of the observation sampling error statistics are determined from an ensemble of background or first-guess fields or from the analysis of the raw data from instrumented aircraft, Doppler lidars, or radar profilers. The spatial variations of the sampling error are referenced to the local turbulence conditions at each analysis coordinate and therefore each observation can have a different observation error for each nearby analysis coordinate. The extension of the adaptive assimilation concept to include the spatial variations in observation error for statistical interpolation, 3D-Var, 4D-Var, extended Kalman filtering, and ensemble Kalman filtering is also presented for the traditional meaning of observation error, i.e. each observation is assigned a single error. The conditional analysis error is derived for a single observation at the analysis coordinate and multiple observations around the analysis point. Example calculations of the conditional analysis error are presented for a few simple set of observation and measurement geometries to demonstrate the impact of the spatially variable observation errors

  14. Modular and Adaptive Control of Sound Processing

    NASA Astrophysics Data System (ADS)

    van Nort, Douglas

    parameters. In this view, desired gestural dynamics and sonic response are achieved through modular construction of mapping layers that are themselves subject to parametric control. Complementing this view of the design process, the work concludes with an approach in which the creation of gestural control/sound dynamics are considered in the low-level of the underlying sound model. The result is an adaptive system that is specialized to noise-based transformations that are particularly relevant in an electroacoustic music context. Taken together, these different approaches to design and evaluation result in a unified framework for creation of an instrumental system. The key point is that this framework addresses the influence that mapping structure and control dynamics have on the perceived feel of the instrument. Each of the results illustrate this using either top-down or bottom-up approaches that consider musical control context, thereby pointing to the greater potential for refined sonic articulation that can be had by combining them in the design process.

  15. Reflective Assessment: Including Students in the Assessment Process

    ERIC Educational Resources Information Center

    Bond, John B.

    2007-01-01

    Over the last decade alternative assessment strategies have become an important part of the debate regarding the reform and restructuring of American education. The purpose of assessment should be to improve student learning, which means it should be integral to the teaching and learning process. For this to occur, a seamlessness needs to exist…

  16. Short residence time coal liquefaction process including catalytic hydrogenation

    DOEpatents

    Anderson, Raymond P.; Schmalzer, David K.; Wright, Charles H.

    1982-05-18

    Normally solid dissolved coal product and a distillate liquid product are produced by continuously passing a feed slurry comprising raw feed coal and a recycle solvent oil and/or slurry together with hydrogen to a preheating-reaction zone (26, alone, or 26 together with 42), the hydrogen pressure in the preheating-reaction zone being at least 1500 psig (105 kg/cm.sup.2), reacting the slurry in the preheating-reaction zone (26, or 26 with 42) at a temperature in the range of between about 455.degree. and about 500.degree. C. to dissolve the coal to form normally liquid coal and normally solid dissolved coal. A total slurry residence time is maintained in the reaction zone ranging from a finite value from about 0 to about 0.2 hour, and reaction effluent is continuously and directly contacted with a quenching fluid (40, 68) to substantially immediately reduce the temperature of the reaction effluent to below 425.degree. C. to substantially inhibit polymerization so that the yield of insoluble organic matter comprises less than 9 weight percent of said feed coal on a moisture-free basis. The reaction is performed under conditions of temperature, hydrogen pressure and residence time such that the quantity of distillate liquid boiling within the range C.sub.5 -454.degree. C. is an amount at least equal to that obtainable by performing the process under the same condition except for a longer total slurry residence time, e.g., 0.3 hour. Solvent boiling range liquid is separated from the reaction effluent (83) and recycled as process solvent (16). The amount of solvent boiling range liquid is sufficient to provide at least 80 weight percent of that required to maintain the process in overall solvent balance.

  17. Short residence time coal liquefaction process including catalytic hydrogenation

    DOEpatents

    Anderson, R.P.; Schmalzer, D.K.; Wright, C.H.

    1982-05-18

    Normally solid dissolved coal product and a distillate liquid product are produced by continuously passing a feed slurry comprising raw feed coal and a recycle solvent oil and/or slurry together with hydrogen to a preheating-reaction zone, the hydrogen pressure in the preheating-reaction zone being at least 1,500 psig (105 kg/cm[sup 2]), reacting the slurry in the preheating-reaction zone at a temperature in the range of between about 455 and about 500 C to dissolve the coal to form normally liquid coal and normally solid dissolved coal. A total slurry residence time is maintained in the reaction zone ranging from a finite value from about 0 to about 0.2 hour, and reaction effluent is continuously and directly contacted with a quenching fluid to substantially immediately reduce the temperature of the reaction effluent to below 425 C to substantially inhibit polymerization so that the yield of insoluble organic matter comprises less than 9 weight percent of said feed coal on a moisture-free basis. The reaction is performed under conditions of temperature, hydrogen pressure and residence time such that the quantity of distillate liquid boiling within the range C[sub 5]-454 C is an amount at least equal to that obtainable by performing the process under the same condition except for a longer total slurry residence time, e.g., 0.3 hour. Solvent boiling range liquid is separated from the reaction effluent and recycled as process solvent. The amount of solvent boiling range liquid is sufficient to provide at least 80 weight percent of that required to maintain the process in overall solvent balance. 6 figs.

  18. Inferring time derivatives including cell growth rates using Gaussian processes

    PubMed Central

    Swain, Peter S.; Stevenson, Keiran; Leary, Allen; Montano-Gutierrez, Luis F.; Clark, Ivan B.N.; Vogel, Jackie; Pilizota, Teuta

    2016-01-01

    Often the time derivative of a measured variable is of as much interest as the variable itself. For a growing population of biological cells, for example, the population's growth rate is typically more important than its size. Here we introduce a non-parametric method to infer first and second time derivatives as a function of time from time-series data. Our approach is based on Gaussian processes and applies to a wide range of data. In tests, the method is at least as accurate as others, but has several advantages: it estimates errors both in the inference and in any summary statistics, such as lag times, and allows interpolation with the corresponding error estimation. As illustrations, we infer growth rates of microbial cells, the rate of assembly of an amyloid fibril and both the speed and acceleration of two separating spindle pole bodies. Our algorithm should thus be broadly applicable. PMID:27941811

  19. Inferring time derivatives including cell growth rates using Gaussian processes

    NASA Astrophysics Data System (ADS)

    Swain, Peter S.; Stevenson, Keiran; Leary, Allen; Montano-Gutierrez, Luis F.; Clark, Ivan B. N.; Vogel, Jackie; Pilizota, Teuta

    2016-12-01

    Often the time derivative of a measured variable is of as much interest as the variable itself. For a growing population of biological cells, for example, the population's growth rate is typically more important than its size. Here we introduce a non-parametric method to infer first and second time derivatives as a function of time from time-series data. Our approach is based on Gaussian processes and applies to a wide range of data. In tests, the method is at least as accurate as others, but has several advantages: it estimates errors both in the inference and in any summary statistics, such as lag times, and allows interpolation with the corresponding error estimation. As illustrations, we infer growth rates of microbial cells, the rate of assembly of an amyloid fibril and both the speed and acceleration of two separating spindle pole bodies. Our algorithm should thus be broadly applicable.

  20. Adaptive mesh refinement for stochastic reaction-diffusion processes

    SciTech Connect

    Bayati, Basil; Chatelain, Philippe; Koumoutsakos, Petros

    2011-01-01

    We present an algorithm for adaptive mesh refinement applied to mesoscopic stochastic simulations of spatially evolving reaction-diffusion processes. The transition rates for the diffusion process are derived on adaptive, locally refined structured meshes. Convergence of the diffusion process is presented and the fluctuations of the stochastic process are verified. Furthermore, a refinement criterion is proposed for the evolution of the adaptive mesh. The method is validated in simulations of reaction-diffusion processes as described by the Fisher-Kolmogorov and Gray-Scott equations.

  1. A systematic process for adaptive concept exploration

    NASA Astrophysics Data System (ADS)

    Nixon, Janel Nicole

    several common challenges to the creation of quantitative modeling and simulation environments. Namely, a greater number of alternative solutions imply a greater number of design variables as well as larger ranges on those variables. This translates to a high-dimension combinatorial problem. As the size and dimensionality of the solution space gets larger, the number of physically impossible solutions within that space greatly increases. Thus, the ratio of feasible design space to infeasible space decreases, making it much harder to not only obtain a good quantitative sample of the space, but to also make sense of that data. This is especially the case in the early stages of design, where it is not practical to dedicate a great deal of resources to performing thorough, high-fidelity analyses on all the potential solutions. To make quantitative analyses feasible in these early stages of design, a method is needed that allows for a relatively sparse set of information to be collected quickly and efficiently, and yet, that information needs to be meaningful enough with which to base a decision. The method developed to address this need uses a Systematic Process for Adaptive Concept Exploration (SPACE). In the SPACE method, design space exploration occurs in a sequential fashion; as data is acquired, the sampling scheme adapts to the specific problem at hand. Previously gathered data is used to make inferences about the nature of the problem so that future samples can be taken from the more interesting portions of the design space. Furthermore, the SPACE method identifies those analyses that have significant impacts on the relationships being modeled, so that effort can be focused on acquiring only the most pertinent information. The SPACE method uses a four-part sampling scheme to efficiently uncover the parametric relationships between the design variables and responses. Step 1 aims to identify the location of infeasible space within the region of interest using an initial

  2. Adaptive processing of fractions--evidence from eye-tracking.

    PubMed

    Huber, S; Moeller, K; Nuerk, H-C

    2014-05-01

    Recent evidence indicated that fraction pair type determined whether a particular fraction is processed holistically, componentially or in a hybrid manner. Going beyond previous studies, we investigated how participants adapt their processing of fractions not only to fraction type, but also to experimental context. To examine adaptation in fraction processing, we recorded participants' eye-fixation behaviour in a fraction magnitude comparison task. Participants' eye fixation behaviour indicated componential processing of fraction pairs with common components for which the decision-relevant components are easy to identify. Importantly, we observed that fraction processing was adapted to experimental context: Evidence for componential processing was stronger, when experimental context allowed valid expectations about which components are decision-relevant. Taken together, we conclude that fraction processing is adaptive beyond the comparison of different fraction types, because participants continuously adjust to the experimental context in which fractions are processed.

  3. Neuronal Adaptive Mechanisms Underlying Intelligent Information Processing

    DTIC Science & Technology

    1982-05-01

    omuter Procram The program consists of three functional units: stimulus presentation and data collection, histogram generation and display, and benavioral...sequence for ten second trials of adaptation, conditioning, extinction, or delayed HS paradigms. Timing of stimuli can be generated • . .. -?’ _-, a’. Ah...are generated from the data and displayed four each on Mime 100 and VT105 video terminals. The histograms are averages of three trials and are

  4. Adaptive Constructive Processes and the Future of Memory

    ERIC Educational Resources Information Center

    Schacter, Daniel L.

    2012-01-01

    Memory serves critical functions in everyday life but is also prone to error. This article examines adaptive constructive processes, which play a functional role in memory and cognition but can also produce distortions, errors, and illusions. The article describes several types of memory errors that are produced by adaptive constructive processes…

  5. Adaptation to Work: An Exploration of Processes and Outcomes.

    ERIC Educational Resources Information Center

    Ashley, William L.; And Others

    A study of adaptation to work as both a process and an outcome was conducted. The study was conducted by personal interview that probed adaptation with respect to work's organizational, performance, interpersonal, responsibility, and affective aspects; and by questionnaire using the same aspects. The population studied consisted of persons without…

  6. Adaptive Memory: Is Survival Processing Special?

    ERIC Educational Resources Information Center

    Nairne, James S.; Pandeirada, Josefa N. S.

    2008-01-01

    Do the operating characteristics of memory continue to bear the imprints of ancestral selection pressures? Previous work in our laboratory has shown that human memory may be specially tuned to retain information processed in terms of its survival relevance. A few seconds of survival processing in an incidental learning context can produce recall…

  7. Dosimetric evaluation of three adaptive strategies for prostate cancer treatment including pelvic lymph nodes irradiation

    SciTech Connect

    Cantin, Audrey; Gingras, Luc; Archambault, Louis; Lachance, Bernard; Foster, William; Goudreault, Julie

    2015-12-15

    Purpose: The movements of the prostate relative to the pelvic lymph nodes during intensity-modulated radiation therapy treatment can limit margin reduction and affect the protection of the organs at risk (OAR). In this study, the authors performed an analysis of three adaptive treatment strategies that combine information from both bony and gold marker registrations. The robustness of those treatments against the interfraction prostate movements was evaluated. Methods: A retrospective study was conducted on five prostate cancer patients with 7–13 daily cone-beam CTs (CBCTs). The clinical target volumes (CTVs) consisting of pelvic lymph nodes, prostate, and seminal vesicles as well as the OARs were delineated on each CBCT and the initial CT. Three adaptive strategies were analyzed. Two of these methods relied on a two-step patient positioning at each fraction. First step: a bony registration was used to deliver the nodal CTV prescription. Second step: a gold marker registration was then used either to (1) complete the dose delivered to the prostate (complement); (2) or give almost the entire prescription to the prostate with a weak dose gradient between the targets to compensate for possible motions (gradient). The third method (COR) used a pool of precalculated plans based on images acquired at previous treatment fractions. At each new fraction, a plan is selected from that pool based on the daily position of prostate center-of-mass. The dosimetric comparison was conducted and results are presented with and without the systematic shift in the prostate position on the CT planning. The adaptive strategies were compared to the current clinical standard where all fractions are treated with the initial nonadaptive plan. Results: The minimum daily prostate D{sub 95%} is improved by 2%, 9%, and 6% for the complement, the gradient, and the COR approaches, respectively, compared to the nonadaptive method. The average nodal CTV D{sub 95%} remains constant across the

  8. Sensory Processing Subtypes in Autism: Association with Adaptive Behavior

    ERIC Educational Resources Information Center

    Lane, Alison E.; Young, Robyn L.; Baker, Amy E. Z.; Angley, Manya T.

    2010-01-01

    Children with autism are frequently observed to experience difficulties in sensory processing. This study examined specific patterns of sensory processing in 54 children with autistic disorder and their association with adaptive behavior. Model-based cluster analysis revealed three distinct sensory processing subtypes in autism. These subtypes…

  9. Common formalism for adaptive identification in signal processing and control

    NASA Astrophysics Data System (ADS)

    Macchi, O.

    1991-08-01

    The transversal and recursive approaches to adaptive identification are compared. ARMA modeling in signal processing, and identification in the indirect approach to control are developed in parallel. Adaptivity succeeds because the estimate is a linear function of the variable parameters for transversal identification. Control and signal processing can be imbedded in a unified well-established formalism that guarantees convergence of the adaptive parameters. For recursive identification, the estimate is a nonlinear function of the parameters, possibly resulting in nonuniqueness of the solution, in wandering and even instability of adaptive algorithms. The requirement for recursivity originates in the structure of the signal (MA-part) in signal processing. It is caused by the output measurement noise in control.

  10. Adaptive model predictive process control using neural networks

    DOEpatents

    Buescher, Kevin L.; Baum, Christopher C.; Jones, Roger D.

    1997-01-01

    A control system for controlling the output of at least one plant process output parameter is implemented by adaptive model predictive control using a neural network. An improved method and apparatus provides for sampling plant output and control input at a first sampling rate to provide control inputs at the fast rate. The MPC system is, however, provided with a network state vector that is constructed at a second, slower rate so that the input control values used by the MPC system are averaged over a gapped time period. Another improvement is a provision for on-line training that may include difference training, curvature training, and basis center adjustment to maintain the weights and basis centers of the neural in an updated state that can follow changes in the plant operation apart from initial off-line training data.

  11. Adaptive model predictive process control using neural networks

    DOEpatents

    Buescher, K.L.; Baum, C.C.; Jones, R.D.

    1997-08-19

    A control system for controlling the output of at least one plant process output parameter is implemented by adaptive model predictive control using a neural network. An improved method and apparatus provides for sampling plant output and control input at a first sampling rate to provide control inputs at the fast rate. The MPC system is, however, provided with a network state vector that is constructed at a second, slower rate so that the input control values used by the MPC system are averaged over a gapped time period. Another improvement is a provision for on-line training that may include difference training, curvature training, and basis center adjustment to maintain the weights and basis centers of the neural in an updated state that can follow changes in the plant operation apart from initial off-line training data. 46 figs.

  12. On adaptive robustness approach to Anti-Jam signal processing

    NASA Astrophysics Data System (ADS)

    Poberezhskiy, Y. S.; Poberezhskiy, G. Y.

    An effective approach to exploiting statistical differences between desired and jamming signals named adaptive robustness is proposed and analyzed in this paper. It combines conventional Bayesian, adaptive, and robust approaches that are complementary to each other. This combining strengthens the advantages and mitigates the drawbacks of the conventional approaches. Adaptive robustness is equally applicable to both jammers and their victim systems. The capabilities required for realization of adaptive robustness in jammers and victim systems are determined. The employment of a specific nonlinear robust algorithm for anti-jam (AJ) processing is described and analyzed. Its effectiveness in practical situations has been proven analytically and confirmed by simulation. Since adaptive robustness can be used by both sides in electronic warfare, it is more advantageous for the fastest and most intelligent side. Many results obtained and discussed in this paper are also applicable to commercial applications such as communications in unregulated or poorly regulated frequency ranges and systems with cognitive capabilities.

  13. Adaptation of postural control to perturbations--a process that initiates long-term motor memory.

    PubMed

    Tjernström, F; Fransson, P-A; Hafström, A; Magnusson, M

    2002-02-01

    The objective was to investigate postural control adaptation during daily repeated posturography with vibratory calf stimulation. The posturography was performed with eyes open and closed daily for 5 days and after 90 days on 12 healthy subjects. The postural control adaptation could be described as two separate processes, a rapid adaptation during the test progress and a long-term habituation between consecutive test days. The adaptive improvements gained during the 5 days consecutive testing, largely remained 90 days later but seemed restricted to the same test situation. The findings suggest that balance rehabilitation should include a variety of repeated exercises, which are sufficiently long to induce habituation.

  14. Strategy for adaptive process control for a column flotation unit

    SciTech Connect

    Karr, C.L.; Ferguson, C.R.

    1994-12-31

    Researchers at the U.S. Bureau of Mines (USBM) have developed adaptive process control systems in which genetic algorithms (GAs) are used to augment fuzzy logic controllers (FLCs). Together, GAs and FLCs possess the capabilities necessary to produce powerful, efficient, and robust adaptive control systems. To perform efficiently, such control systems require a control element to manipulate the problem environment, an analysis element to recognize changes in the problem environment, and a learning element to adjust to the changes in the problem environment. In this paper, the details of an ongoing research effort to develop and implement an adaptive process control system for a column flotation unit are discussed. Column flotation units are used extensively in the mineral processing industry to recover valuable minerals from their ores.

  15. Modeling coupled Thermo-Hydro-Mechanical processes including plastic deformation in geological porous media

    NASA Astrophysics Data System (ADS)

    Kelkar, S.; Karra, S.; Pawar, R. J.; Zyvoloski, G.

    2012-12-01

    There has been an increasing interest in the recent years in developing computational tools for analyzing coupled thermal, hydrological and mechanical (THM) processes that occur in geological porous media. This is mainly due to their importance in applications including carbon sequestration, enhanced geothermal systems, oil and gas production from unconventional sources, degradation of Arctic permafrost, and nuclear waste isolation. Large changes in pressures, temperatures and saturation can result due to injection/withdrawal of fluids or emplaced heat sources. These can potentially lead to large changes in the fluid flow and mechanical behavior of the formation, including shear and tensile failure on pre-existing or induced fractures and the associated permeability changes. Due to this, plastic deformation and large changes in material properties such as permeability and porosity can be expected to play an important role in these processes. We describe a general purpose computational code FEHM that has been developed for the purpose of modeling coupled THM processes during multi-phase fluid flow and transport in fractured porous media. The code uses a continuum mechanics approach, based on control volume - finite element method. It is designed to address spatial scales on the order of tens of centimeters to tens of kilometers. While large deformations are important in many situations, we have adapted the small strain formulation as useful insight can be obtained in many problems of practical interest with this approach while remaining computationally manageable. Nonlinearities in the equations and the material properties are handled using a full Jacobian Newton-Raphson technique. Stress-strain relationships are assumed to follow linear elastic/plastic behavior. The code incorporates several plasticity models such as von Mises, Drucker-Prager, and also a large suite of models for coupling flow and mechanical deformation via permeability and stresses

  16. Adaptation to leftward-shifting prisms enhances local processing in healthy individuals.

    PubMed

    Reed, Scott A; Dassonville, Paul

    2014-04-01

    In healthy individuals, adaptation to left-shifting prisms has been shown to simulate the symptoms of hemispatial neglect, including a reduction in global processing that approximates the local bias observed in neglect patients. The current study tested whether leftward prism adaptation can more specifically enhance local processing abilities. In three experiments, the impact of local and global processing was assessed through tasks that measure susceptibility to illusions that are known to be driven by local or global contextual effects. Susceptibility to the rod-and-frame illusion - an illusion disproportionately driven by both local and global effects depending on frame size - was measured before and after adaptation to left- and right-shifting prisms. A significant increase in rod-and-frame susceptibility was found for the left-shifting prism group, suggesting that adaptation caused an increase in local processing effects. The results of a second experiment confirmed that leftward prism adaptation enhances local processing, as assessed with susceptibility to the simultaneous-tilt illusion. A final experiment employed a more specific measure of the global effect typically associated with the rod-and-frame illusion, and found that although the global effect was somewhat diminished after leftward prism adaptation, the trend failed to reach significance (p=.078). Rightward prism adaptation had no significant effects on performance in any of the experiments. Combined, these findings indicate that leftward prism adaptation in healthy individuals can simulate the local processing bias of neglect patients primarily through an increased sensitivity to local visual cues, and confirm that prism adaptation not only modulates lateral shifts of attention, but also prompts shifts from one level of processing to another.

  17. Adaptation to Leftward-shifting Prisms Enhances Local Processing in Healthy Individuals

    PubMed Central

    Reed, Scott A.; Dassonville, Paul

    2014-01-01

    In healthy individuals, adaptation to left-shifting prisms has been shown to simulate the symptoms of hemispatial neglect, including a reduction in global processing that approximates the local bias observed in neglect patients. The current study tested whether leftward prism adaptation can more specifically enhance local processing abilities. In three experiments, the impact of local and global processing was assessed through tasks that measure susceptibility to illusions that are known to be driven by local or global contextual effects. Susceptibility to the rod-and-frame illusion – an illusion disproportionately driven by both local and global effects depending on frame size – was measured before and after adaptation to left- and right-shifting prisms. A significant increase in rod-and-frame susceptibility was found for the left-shifting prism group, suggesting that adaptation caused an increase in local processing effects. The results of a second experiment confirmed that leftward prism adaptation enhances local processing, as assessed with susceptibility to the simultaneous-tilt illusion. A final experiment employed a more specific measure of the global effect typically associated with the rod-andframe illusion, and found that although the global effect was somewhat diminished after leftward prism adaptation, the trend failed to reach significance (p = .078). Rightward prism adaptation had no significant effects on performance in any of the experiments. Combined, these findings indicate that leftward prism adaptation in healthy individuals can simulate the local processing bias of neglect patients primarily through an increased sensitivity to local visual cues, and confirm that prism adaptation not only modulates lateral shifts of attention, but also prompts shifts from one level of processing to another. PMID:24560913

  18. Adapting the Transtheoretical Model of Change to the Bereavement Process

    ERIC Educational Resources Information Center

    Calderwood, Kimberly A.

    2011-01-01

    Theorists currently believe that bereaved people undergo some transformation of self rather than returning to their original state. To advance our understanding of this process, this article presents an adaptation of Prochaska and DiClemente's transtheoretical model of change as it could be applied to the journey that bereaved individuals…

  19. Examining Teacher Thinking: Constructing a Process to Design Curricular Adaptations.

    ERIC Educational Resources Information Center

    Udvari-Solner, Alice

    1996-01-01

    This description of a curricular adaptation decision-making process focuses on tenets of reflective practice as teachers design instruction for students in heterogeneous classrooms. A case example illustrates how an elementary teaching team transformed lessons to accommodate a wide range of learners in a multiage first- and second-grade classroom.…

  20. Behavioral training promotes multiple adaptive processes following acute hearing loss

    PubMed Central

    Keating, Peter; Rosenior-Patten, Onayomi; Dahmen, Johannes C; Bell, Olivia; King, Andrew J

    2016-01-01

    The brain possesses a remarkable capacity to compensate for changes in inputs resulting from a range of sensory impairments. Developmental studies of sound localization have shown that adaptation to asymmetric hearing loss can be achieved either by reinterpreting altered spatial cues or by relying more on those cues that remain intact. Adaptation to monaural deprivation in adulthood is also possible, but appears to lack such flexibility. Here we show, however, that appropriate behavioral training enables monaurally-deprived adult humans to exploit both of these adaptive processes. Moreover, cortical recordings in ferrets reared with asymmetric hearing loss suggest that these forms of plasticity have distinct neural substrates. An ability to adapt to asymmetric hearing loss using multiple adaptive processes is therefore shared by different species and may persist throughout the lifespan. This highlights the fundamental flexibility of neural systems, and may also point toward novel therapeutic strategies for treating sensory disorders. DOI: http://dx.doi.org/10.7554/eLife.12264.001 PMID:27008181

  1. Adaptive beamforming for array signal processing in aeroacoustic measurements.

    PubMed

    Huang, Xun; Bai, Long; Vinogradov, Igor; Peers, Edward

    2012-03-01

    Phased microphone arrays have become an important tool in the localization of noise sources for aeroacoustic applications. In most practical aerospace cases the conventional beamforming algorithm of the delay-and-sum type has been adopted. Conventional beamforming cannot take advantage of knowledge of the noise field, and thus has poorer resolution in the presence of noise and interference. Adaptive beamforming has been used for more than three decades to address these issues and has already achieved various degrees of success in areas of communication and sonar. In this work an adaptive beamforming algorithm designed specifically for aeroacoustic applications is discussed and applied to practical experimental data. It shows that the adaptive beamforming method could save significant amounts of post-processing time for a deconvolution method. For example, the adaptive beamforming method is able to reduce the DAMAS computation time by at least 60% for the practical case considered in this work. Therefore, adaptive beamforming can be considered as a promising signal processing method for aeroacoustic measurements.

  2. Adaptive control of surface finish in automated turning processes

    NASA Astrophysics Data System (ADS)

    García-Plaza, E.; Núñez, P. J.; Martín, A. R.; Sanz, A.

    2012-04-01

    The primary aim of this study was to design and develop an on-line control system of finished surfaces in automated machining process by CNC turning. The control system consisted of two basic phases: during the first phase, surface roughness was monitored through cutting force signals; the second phase involved a closed-loop adaptive control system based on data obtained during the monitoring of the cutting process. The system ensures that surfaces roughness is maintained at optimum values by adjusting the feed rate through communication with the PLC of the CNC machine. A monitoring and adaptive control system has been developed that enables the real-time monitoring of surface roughness during CNC turning operations. The system detects and prevents faults in automated turning processes, and applies corrective measures during the cutting process that raise quality and reliability reducing the need for quality control.

  3. MEMLS3&a: Microwave Emission Model of Layered Snowpacks adapted to include backscattering

    NASA Astrophysics Data System (ADS)

    Proksch, M.; Mätzler, C.; Wiesmann, A.; Lemmetyinen, J.; Schwank, M.; Löwe, H.; Schneebeli, M.

    2015-03-01

    The Microwave Emission Model of Layered Snowpacks (MEMLS) was originally developed for microwave emissions of snowpacks in the frequency range 5-100 GHz. It is based on six-flux theory to describe radiative transfer in snow including absorption, multiple volume scattering, radiation trapping due to internal reflection and a combination of coherent and incoherent superposition of reflections between horizontal layer interfaces. Here we introduce MEMLS3&a, an extension of MEMLS, which includes a backscatter model for active microwave remote sensing of snow. The reflectivity is decomposed into diffuse and specular components. Slight undulations of the snow surface are taken into account. The treatment of like and cross polarization is accomplished by an empirical splitting parameter q. MEMLS3&a (as well as MEMLS) is set up in a way that snow input parameters can be derived by objective measurement methods which avoids fitting procedures of the scattering efficiency of snow, required by several other models. For the validation of the model we have used a combination of active and passive measurements from the NoSREx campaign in Sodankylä, Finland. We find a reasonable agreement between the measurements and simulations, subject to uncertainties in hitherto unmeasured input parameters of the backscatter model. The model is written in MATLAB and the code is publicly available for download through the following website: http://www.iapmw.unibe.ch/research/projects/snowtools/memls.html.

  4. MEMLS3&a: Microwave Emission Model of Layered Snowpacks adapted to include backscattering

    NASA Astrophysics Data System (ADS)

    Proksch, M.; Mätzler, C.; Wiesmann, A.; Lemmetyinen, J.; Schwank, M.; Löwe, H.; Schneebeli, M.

    2015-08-01

    The Microwave Emission Model of Layered Snowpacks (MEMLS) was originally developed for microwave emissions of snowpacks in the frequency range 5-100 GHz. It is based on six-flux theory to describe radiative transfer in snow including absorption, multiple volume scattering, radiation trapping due to internal reflection and a combination of coherent and incoherent superposition of reflections between horizontal layer interfaces. Here we introduce MEMLS3&a, an extension of MEMLS, which includes a backscatter model for active microwave remote sensing of snow. The reflectivity is decomposed into diffuse and specular components. Slight undulations of the snow surface are taken into account. The treatment of like- and cross-polarization is accomplished by an empirical splitting parameter q. MEMLS3&a (as well as MEMLS) is set up in a way that snow input parameters can be derived by objective measurement methods which avoid fitting procedures of the scattering efficiency of snow, required by several other models. For the validation of the model we have used a combination of active and passive measurements from the NoSREx (Nordic Snow Radar Experiment) campaign in Sodankylä, Finland. We find a reasonable agreement between the measurements and simulations, subject to uncertainties in hitherto unmeasured input parameters of the backscatter model. The model is written in Matlab and the code is publicly available for download through the following website: http://www.iapmw.unibe.ch/research/projects/snowtools/memls.html.

  5. Adaptive Signal Processing Testbed signal excision software: User's manual

    NASA Astrophysics Data System (ADS)

    Parliament, Hugh A.

    1992-05-01

    The Adaptive Signal Processing Testbed (ASPT) signal excision software is a set of programs that provide real-time processing functions for the excision of interfering tones from a live spread-spectrum signal as well as off-line functions for the analysis of the effectiveness of the excision technique. The processing functions provided by the ASPT signal excision software are real-time adaptive filtering of live data, storage to disk, and file sorting and conversion. The main off-line analysis function is bit error determination. The purpose of the software is to measure the effectiveness of an adaptive filtering algorithm to suppress interfering or jamming signals in a spread spectrum signal environment. A user manual for the software is provided, containing information on the different software components available to perform signal excision experiments: the real-time excision software, excision host program, file processing utilities, and despreading and bit error rate determination software. In addition, information is presented describing the excision algorithm implemented, the real-time processing framework, the steps required to add algorithms to the system, the processing functions used in despreading, and description of command sequences for post-run analysis of the data.

  6. Adaptive process control using fuzzy logic and genetic algorithms

    NASA Technical Reports Server (NTRS)

    Karr, C. L.

    1993-01-01

    Researchers at the U.S. Bureau of Mines have developed adaptive process control systems in which genetic algorithms (GA's) are used to augment fuzzy logic controllers (FLC's). GA's are search algorithms that rapidly locate near-optimum solutions to a wide spectrum of problems by modeling the search procedures of natural genetics. FLC's are rule based systems that efficiently manipulate a problem environment by modeling the 'rule-of-thumb' strategy used in human decision making. Together, GA's and FLC's possess the capabilities necessary to produce powerful, efficient, and robust adaptive control systems. To perform efficiently, such control systems require a control element to manipulate the problem environment, and a learning element to adjust to the changes in the problem environment. Details of an overall adaptive control system are discussed. A specific laboratory acid-base pH system is used to demonstrate the ideas presented.

  7. Adaptive Process Control with Fuzzy Logic and Genetic Algorithms

    NASA Technical Reports Server (NTRS)

    Karr, C. L.

    1993-01-01

    Researchers at the U.S. Bureau of Mines have developed adaptive process control systems in which genetic algorithms (GA's) are used to augment fuzzy logic controllers (FLC's). GA's are search algorithms that rapidly locate near-optimum solutions to a wide spectrum of problems by modeling the search procedures of natural genetics. FLC's are rule based systems that efficiently manipulate a problem environment by modeling the 'rule-of-thumb' strategy used in human decision-making. Together, GA's and FLC's possess the capabilities necessary to produce powerful, efficient, and robust adaptive control systems. To perform efficiently, such control systems require a control element to manipulate the problem environment, an analysis element to recognize changes in the problem environment, and a learning element to adjust to the changes in the problem environment. Details of an overall adaptive control system are discussed. A specific laboratory acid-base pH system is used to demonstrate the ideas presented.

  8. Frequency Adaptability and Waveform Design for OFDM Radar Space-Time Adaptive Processing

    SciTech Connect

    Sen, Satyabrata; Glover, Charles Wayne

    2012-01-01

    We propose an adaptive waveform design technique for an orthogonal frequency division multiplexing (OFDM) radar signal employing a space-time adaptive processing (STAP) technique. We observe that there are inherent variabilities of the target and interference responses in the frequency domain. Therefore, the use of an OFDM signal can not only increase the frequency diversity of our system, but also improve the target detectability by adaptively modifying the OFDM coefficients in order to exploit the frequency-variabilities of the scenario. First, we formulate a realistic OFDM-STAP measurement model considering the sparse nature of the target and interference spectra in the spatio-temporal domain. Then, we show that the optimal STAP-filter weight-vector is equal to the generalized eigenvector corresponding to the minimum generalized eigenvalue of the interference and target covariance matrices. With numerical examples we demonstrate that the resultant OFDM-STAP filter-weights are adaptable to the frequency-variabilities of the target and interference responses, in addition to the spatio-temporal variabilities. Hence, by better utilizing the frequency variabilities, we propose an adaptive OFDM-waveform design technique, and consequently gain a significant amount of STAP-performance improvement.

  9. Thermodynamic Costs of Information Processing in Sensory Adaptation

    PubMed Central

    Sartori, Pablo; Granger, Léo; Lee, Chiu Fan; Horowitz, Jordan M.

    2014-01-01

    Biological sensory systems react to changes in their surroundings. They are characterized by fast response and slow adaptation to varying environmental cues. Insofar as sensory adaptive systems map environmental changes to changes of their internal degrees of freedom, they can be regarded as computational devices manipulating information. Landauer established that information is ultimately physical, and its manipulation subject to the entropic and energetic bounds of thermodynamics. Thus the fundamental costs of biological sensory adaptation can be elucidated by tracking how the information the system has about its environment is altered. These bounds are particularly relevant for small organisms, which unlike everyday computers, operate at very low energies. In this paper, we establish a general framework for the thermodynamics of information processing in sensing. With it, we quantify how during sensory adaptation information about the past is erased, while information about the present is gathered. This process produces entropy larger than the amount of old information erased and has an energetic cost bounded by the amount of new information written to memory. We apply these principles to the E. coli's chemotaxis pathway during binary ligand concentration changes. In this regime, we quantify the amount of information stored by each methyl group and show that receptors consume energy in the range of the information-theoretic minimum. Our work provides a basis for further inquiries into more complex phenomena, such as gradient sensing and frequency response. PMID:25503948

  10. Adaptive two-scale edge detection for visual pattern processing

    NASA Astrophysics Data System (ADS)

    Rahman, Zia-Ur; Jobson, Daniel J.; Woodell, Glenn A.

    2009-09-01

    Adaptive methods are defined and experimentally studied for a two-scale edge detection process that mimics human visual perception of edges and is inspired by the parvocellular (P) and magnocellular (M) physiological subsystems of natural vision. This two-channel processing consists of a high spatial acuity/coarse contrast channel (P) and a coarse acuity/fine contrast (M) channel. We perform edge detection after a very strong nonlinear image enhancement that uses smart Retinex image processing. Two conditions that arise from this enhancement demand adaptiveness in edge detection. These conditions are the presence of random noise further exacerbated by the enhancement process and the equally random occurrence of dense textural visual information. We examine how to best deal with both phenomena with an automatic adaptive computation that treats both high noise and dense textures as too much information and gracefully shifts from small-scale to medium-scale edge pattern priorities. This shift is accomplished by using different edge-enhancement schemes that correspond with the P- and M-channels of the human visual system. We also examine the case of adapting to a third image condition-namely, too little visual information-and automatically adjust edge-detection sensitivities when sparse feature information is encountered. When this methodology is applied to a sequence of images of the same scene but with varying exposures and lighting conditions, this edge-detection process produces pattern constancy that is very useful for several imaging applications that rely on image classification in variable imaging conditions.

  11. Adaptive sampling for learning gaussian processes using mobile sensor networks.

    PubMed

    Xu, Yunfei; Choi, Jongeun

    2011-01-01

    This paper presents a novel class of self-organizing sensing agents that adaptively learn an anisotropic, spatio-temporal gaussian process using noisy measurements and move in order to improve the quality of the estimated covariance function. This approach is based on a class of anisotropic covariance functions of gaussian processes introduced to model a broad range of spatio-temporal physical phenomena. The covariance function is assumed to be unknown a priori. Hence, it is estimated by the maximum a posteriori probability (MAP) estimator. The prediction of the field of interest is then obtained based on the MAP estimate of the covariance function. An optimal sampling strategy is proposed to minimize the information-theoretic cost function of the Fisher Information Matrix. Simulation results demonstrate the effectiveness and the adaptability of the proposed scheme.

  12. Adoption: biological and social processes linked to adaptation.

    PubMed

    Grotevant, Harold D; McDermott, Jennifer M

    2014-01-01

    Children join adoptive families through domestic adoption from the public child welfare system, infant adoption through private agencies, and international adoption. Each pathway presents distinctive developmental opportunities and challenges. Adopted children are at higher risk than the general population for problems with adaptation, especially externalizing, internalizing, and attention problems. This review moves beyond the field's emphasis on adoptee-nonadoptee differences to highlight biological and social processes that affect adaptation of adoptees across time. The experience of stress, whether prenatal, postnatal/preadoption, or during the adoption transition, can have significant impacts on the developing neuroendocrine system. These effects can contribute to problems with physical growth, brain development, and sleep, activating cascading effects on social, emotional, and cognitive development. Family processes involving contact between adoptive and birth family members, co-parenting in gay and lesbian adoptive families, and racial socialization in transracially adoptive families affect social development of adopted children into adulthood.

  13. Adaptive Sampling for Learning Gaussian Processes Using Mobile Sensor Networks

    PubMed Central

    Xu, Yunfei; Choi, Jongeun

    2011-01-01

    This paper presents a novel class of self-organizing sensing agents that adaptively learn an anisotropic, spatio-temporal Gaussian process using noisy measurements and move in order to improve the quality of the estimated covariance function. This approach is based on a class of anisotropic covariance functions of Gaussian processes introduced to model a broad range of spatio-temporal physical phenomena. The covariance function is assumed to be unknown a priori. Hence, it is estimated by the maximum a posteriori probability (MAP) estimator. The prediction of the field of interest is then obtained based on the MAP estimate of the covariance function. An optimal sampling strategy is proposed to minimize the information-theoretic cost function of the Fisher Information Matrix. Simulation results demonstrate the effectiveness and the adaptability of the proposed scheme. PMID:22163785

  14. The process of adapting a universal dating abuse prevention program to adolescents exposed to domestic violence.

    PubMed

    Foshee, Vangie A; Dixon, Kimberly S; Ennett, Susan T; Moracco, Kathryn E; Bowling, J Michael; Chang, Ling-Yin; Moss, Jennifer L

    2015-07-01

    Adolescents exposed to domestic violence are at increased risk of dating abuse, yet no evaluated dating abuse prevention programs have been designed specifically for this high-risk population. This article describes the process of adapting Families for Safe Dates (FSD), an evidenced-based universal dating abuse prevention program, to this high-risk population, including conducting 12 focus groups and 107 interviews with the target audience. FSD includes six booklets of dating abuse prevention information, and activities for parents and adolescents to do together at home. We adapted FSD for mothers who were victims of domestic violence, but who no longer lived with the abuser, to do with their adolescents who had been exposed to the violence. Through the adaptation process, we learned that families liked the program structure and valued being offered the program and that some of our initial assumptions about this population were incorrect. We identified practices and beliefs of mother victims and attributes of these adolescents that might increase their risk of dating abuse that we had not previously considered. In addition, we learned that some of the content of the original program generated negative family interactions for some. The findings demonstrate the utility of using a careful process to adapt evidence-based interventions (EBIs) to cultural sub-groups, particularly the importance of obtaining feedback on the program from the target audience. Others can follow this process to adapt EBIs to groups other than the ones for which the original EBI was designed.

  15. The Cultural Adaptation Process during a Short-Term Study Abroad Experience in Swaziland

    ERIC Educational Resources Information Center

    Conner, Nathan W.; Roberts, T. Grady

    2015-01-01

    Globalization continuously shapes our world and influences post-secondary education. This study explored the cultural adaptation process of participants during a short-term study abroad program. Participants experienced stages which included initial feelings, cultural uncertainty, cultural barriers, cultural negativity, academic and career growth,…

  16. Adaptive-optics optical coherence tomography processing using a graphics processing unit.

    PubMed

    Shafer, Brandon A; Kriske, Jeffery E; Kocaoglu, Omer P; Turner, Timothy L; Liu, Zhuolin; Lee, John Jaehwan; Miller, Donald T

    2014-01-01

    Graphics processing units are increasingly being used for scientific computing for their powerful parallel processing abilities, and moderate price compared to super computers and computing grids. In this paper we have used a general purpose graphics processing unit to process adaptive-optics optical coherence tomography (AOOCT) images in real time. Increasing the processing speed of AOOCT is an essential step in moving the super high resolution technology closer to clinical viability.

  17. Chandra Automatic Processing Task Interface: An Adaptable System Architecture

    NASA Astrophysics Data System (ADS)

    Grier, J. D., Jr.; Plummer, D.

    2007-10-01

    The Chandra Automatic Processing Task Interface (CAPTAIN) is an operations interface to Chandra Automatic Processing (AP) that provides detail management and execution of the AP pipelines. In particular, this kind of management is used in Special Automatic Processing (SAP) where there is a need to select specific pipelines that require non-standard handling for reprocessing of a given data set. Standard AP currently contains approximately 200 pipelines with complex interactions between them. As AP has evolved over the life of the mission, so has the number and attributes of these pipelines. As a result, CAPTAIN provides a system architecture capable of managing and adapting to this evolving system. This adaptability has allowed CAPTAIN to also be used to initiate Chandra Source Catalog Automatic Processing (Level~3 AP) and positions it for use with future automatic processing systems. This paper describes the approach to the development of the CAPTAIN system architecture and the maintainable, extensible and reusable software architecture by which it is implemented.

  18. Adaptive processes drive ecomorphological convergent evolution in antwrens (Thamnophilidae).

    PubMed

    Bravo, Gustavo A; Remsen, J V; Brumfield, Robb T

    2014-10-01

    Phylogenetic niche conservatism (PNC) and convergence are contrasting evolutionary patterns that describe phenotypic similarity across independent lineages. Assessing whether and how adaptive processes give origin to these patterns represent a fundamental step toward understanding phenotypic evolution. Phylogenetic model-based approaches offer the opportunity not only to distinguish between PNC and convergence, but also to determine the extent that adaptive processes explain phenotypic similarity. The Myrmotherula complex in the Neotropical family Thamnophilidae is a polyphyletic group of sexually dimorphic small insectivorous forest birds that are relatively homogeneous in size and shape. Here, we integrate a comprehensive species-level molecular phylogeny of the Myrmotherula complex with morphometric and ecological data within a comparative framework to test whether phenotypic similarity is described by a pattern of PNC or convergence, and to identify evolutionary mechanisms underlying body size and shape evolution. We show that antwrens in the Myrmotherula complex represent distantly related clades that exhibit adaptive convergent evolution in body size and divergent evolution in body shape. Phenotypic similarity in the group is primarily driven by their tendency to converge toward smaller body sizes. Differences in body size and shape across lineages are associated to ecological and behavioral factors.

  19. Optimal and adaptive methods of processing hydroacoustic signals (review)

    NASA Astrophysics Data System (ADS)

    Malyshkin, G. S.; Sidel'nikov, G. B.

    2014-09-01

    Different methods of optimal and adaptive processing of hydroacoustic signals for multipath propagation and scattering are considered. Advantages and drawbacks of the classical adaptive (Capon, MUSIC, and Johnson) algorithms and "fast" projection algorithms are analyzed for the case of multipath propagation and scattering of strong signals. The classical optimal approaches to detecting multipath signals are presented. A mechanism of controlled normalization of strong signals is proposed to automatically detect weak signals. The results of simulating the operation of different detection algorithms for a linear equidistant array under multipath propagation and scattering are presented. An automatic detector is analyzed, which is based on classical or fast projection algorithms, which estimates the background proceeding from median filtering or the method of bilateral spatial contrast.

  20. Parallel Processing of Adaptive Meshes with Load Balancing

    NASA Technical Reports Server (NTRS)

    Das, Sajal K.; Harvey, Daniel J.; Biswas, Rupak; Biegel, Bryan (Technical Monitor)

    2001-01-01

    Many scientific applications involve grids that lack a uniform underlying structure. These applications are often also dynamic in nature in that the grid structure significantly changes between successive phases of execution. In parallel computing environments, mesh adaptation of unstructured grids through selective refinement/coarsening has proven to be an effective approach. However, achieving load balance while minimizing interprocessor communication and redistribution costs is a difficult problem. Traditional dynamic load balancers are mostly inadequate because they lack a global view of system loads across processors. In this paper, we propose a novel and general-purpose load balancer that utilizes symmetric broadcast networks (SBN) as the underlying communication topology, and compare its performance with a successful global load balancing environment, called PLUM, specifically created to handle adaptive unstructured applications. Our experimental results on an IBM SP2 demonstrate that the SBN-based load balancer achieves lower redistribution costs than that under PLUM by overlapping processing and data migration.

  1. Process, including PSA and membrane separation, for separating hydrogen from hydrocarbons

    DOEpatents

    Baker, Richard W.; Lokhandwala, Kaaeid A.; He, Zhenjie; Pinnau, Ingo

    2001-01-01

    An improved process for separating hydrogen from hydrocarbons. The process includes a pressure swing adsorption step, a compression/cooling step and a membrane separation step. The membrane step relies on achieving a methane/hydrogen selectivity of at least about 2.5 under the conditions of the process.

  2. Adaptive PCA based fault diagnosis scheme in imperial smelting process.

    PubMed

    Hu, Zhikun; Chen, Zhiwen; Gui, Weihua; Jiang, Bin

    2014-09-01

    In this paper, an adaptive fault detection scheme based on a recursive principal component analysis (PCA) is proposed to deal with the problem of false alarm due to normal process changes in real process. Our further study is also dedicated to develop a fault isolation approach based on Generalized Likelihood Ratio (GLR) test and Singular Value Decomposition (SVD) which is one of general techniques of PCA, on which the off-set and scaling fault can be easily isolated with explicit off-set fault direction and scaling fault classification. The identification of off-set and scaling fault is also applied. The complete scheme of PCA-based fault diagnosis procedure is proposed. The proposed scheme is first applied to Imperial Smelting Process, and the results show that the proposed strategies can be able to mitigate false alarms and isolate faults efficiently.

  3. Adapt

    NASA Astrophysics Data System (ADS)

    Bargatze, L. F.

    2015-12-01

    Active Data Archive Product Tracking (ADAPT) is a collection of software routines that permits one to generate XML metadata files to describe and register data products in support of the NASA Heliophysics Virtual Observatory VxO effort. ADAPT is also a philosophy. The ADAPT concept is to use any and all available metadata associated with scientific data to produce XML metadata descriptions in a consistent, uniform, and organized fashion to provide blanket access to the full complement of data stored on a targeted data server. In this poster, we present an application of ADAPT to describe all of the data products that are stored by using the Common Data File (CDF) format served out by the CDAWEB and SPDF data servers hosted at the NASA Goddard Space Flight Center. These data servers are the primary repositories for NASA Heliophysics data. For this purpose, the ADAPT routines have been used to generate data resource descriptions by using an XML schema named Space Physics Archive, Search, and Extract (SPASE). SPASE is the designated standard for documenting Heliophysics data products, as adopted by the Heliophysics Data and Model Consortium. The set of SPASE XML resource descriptions produced by ADAPT includes high-level descriptions of numerical data products, display data products, or catalogs and also includes low-level "Granule" descriptions. A SPASE Granule is effectively a universal access metadata resource; a Granule associates an individual data file (e.g. a CDF file) with a "parent" high-level data resource description, assigns a resource identifier to the file, and lists the corresponding assess URL(s). The CDAWEB and SPDF file systems were queried to provide the input required by the ADAPT software to create an initial set of SPASE metadata resource descriptions. Then, the CDAWEB and SPDF data repositories were queried subsequently on a nightly basis and the CDF file lists were checked for any changes such as the occurrence of new, modified, or deleted

  4. Prediction and control of chaotic processes using nonlinear adaptive networks

    SciTech Connect

    Jones, R.D.; Barnes, C.W.; Flake, G.W.; Lee, K.; Lewis, P.S.; O'Rouke, M.K.; Qian, S.

    1990-01-01

    We present the theory of nonlinear adaptive networks and discuss a few applications. In particular, we review the theory of feedforward backpropagation networks. We then present the theory of the Connectionist Normalized Linear Spline network in both its feedforward and iterated modes. Also, we briefly discuss the theory of stochastic cellular automata. We then discuss applications to chaotic time series, tidal prediction in Venice lagoon, finite differencing, sonar transient detection, control of nonlinear processes, control of a negative ion source, balancing a double inverted pendulum and design advice for free electron lasers and laser fusion targets.

  5. Landsat ecosystem disturbance adaptive processing system (LEDAPS) algorithm description

    USGS Publications Warehouse

    Schmidt, Gail; Jenkerson, Calli; Masek, Jeffrey; Vermote, Eric; Gao, Feng

    2013-01-01

    The Landsat Ecosystem Disturbance Adaptive Processing System (LEDAPS) software was originally developed by the National Aeronautics and Space Administration–Goddard Space Flight Center and the University of Maryland to produce top-of-atmosphere reflectance from LandsatThematic Mapper and Enhanced Thematic Mapper Plus Level 1 digital numbers and to apply atmospheric corrections to generate a surface-reflectance product.The U.S. Geological Survey (USGS) has adopted the LEDAPS algorithm for producing the Landsat Surface Reflectance Climate Data Record.This report discusses the LEDAPS algorithm, which was implemented by the USGS.

  6. Enhancement Of Visual Evoked Potentials By Adaptive Processing

    NASA Astrophysics Data System (ADS)

    Wolf, W.; Appel, U.; Rauner, H.

    1982-11-01

    Transient evoked potentials (EP) are variations of the on-going electroencephalogram (EEG) in response to the application of sensory stimuli. Since their amplitudes are very small in comparison to the spontaneous EEG, signal extraction methods must be applied to them before their characteristics are measureable. Several signal ex-traction methods which are actually used in EP research are outlined, especially those showing an adaptive characteristic. As a further development, a new method is proposed which considers the on-going EEG preceding the stimulus application for the EP processing. The computational procedure will be described and some preliminary results are given.

  7. Adaptation as process: the future of Darwinism and the legacy of Theodosius Dobzhansky.

    PubMed

    Depew, David J

    2011-03-01

    Conceptions of adaptation have varied in the history of genetic Darwinism depending on whether what is taken to be focal is the process of adaptation, adapted states of populations, or discrete adaptations in individual organisms. I argue that Theodosius Dobzhansky's view of adaptation as a dynamical process contrasts with so-called "adaptationist" views of natural selection figured as "design-without-a-designer" of relatively discrete, enumerable adaptations. Correlated with these respectively process and product oriented approaches to adaptive natural selection are divergent pictures of organisms themselves as developmental wholes or as "bundles" of adaptations. While even process versions of genetical Darwinism are insufficiently sensitive to the fact much of the variation on which adaptive selection works consists of changes in the timing, rate, or location of ontogenetic events, I argue that articulations of the Modern Synthesis influenced by Dobzhansky are more easily reconciled with the recent shift to evolutionary developmentalism than are versions that make discrete adaptations central.

  8. 75 FR 69469 - Health Net, Inc., Claims Processing Group and Systems Configuration Organization, Including On...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-12

    ... Group and Systems Configuration Organization and provided application support and information technology... Employment and Training Administration Health Net, Inc., Claims Processing Group and Systems Configuration Organization, Including On-Site Leased Workers From Kelly Services and Cognizant Technology Solutions,...

  9. Adaptive fuzzy neural network control design via a T-S fuzzy model for a robot manipulator including actuator dynamics.

    PubMed

    Wai, Rong-Jong; Yang, Zhi-Wei

    2008-10-01

    This paper focuses on the development of adaptive fuzzy neural network control (AFNNC), including indirect and direct frameworks for an n-link robot manipulator, to achieve high-precision position tracking. In general, it is difficult to adopt a model-based design to achieve this control objective due to the uncertainties in practical applications, such as friction forces, external disturbances, and parameter variations. In order to cope with this problem, an indirect AFNNC (IAFNNC) scheme and a direct AFNNC (DAFNNC) strategy are investigated without the requirement of prior system information. In these model-free control topologies, a continuous-time Takagi-Sugeno (T-S) dynamic fuzzy model with online learning ability is constructed to represent the system dynamics of an n-link robot manipulator. In the IAFNNC, an FNN estimator is designed to tune the nonlinear dynamic function vector in fuzzy local models, and then, the estimative vector is used to indirectly develop a stable IAFNNC law. In the DAFNNC, an FNN controller is directly designed to imitate a predetermined model-based stabilizing control law, and then, the stable control performance can be achieved by only using joint position information. All the IAFNNC and DAFNNC laws and the corresponding adaptive tuning algorithms for FNN weights are established in the sense of Lyapunov stability analyses to ensure the stable control performance. Numerical simulations and experimental results of a two-link robot manipulator actuated by dc servomotors are given to verify the effectiveness and robustness of the proposed methodologies. In addition, the superiority of the proposed control schemes is indicated in comparison with proportional-differential control, fuzzy-model-based control, T-S-type FNN control, and robust neural fuzzy network control systems.

  10. Method for Fabricating Composite Structures Including Continuous Press Forming and Pultrusion Processing

    NASA Technical Reports Server (NTRS)

    Farley, Gary L. (Inventor)

    1995-01-01

    A method for fabricating composite structures at a low-cost, moderate-to-high production rate is disclosed. A first embodiment of the method includes employing a continuous press forming fabrication process. A second embodiment of the method includes employing a pultrusion process for obtaining composite structures. The methods include coating yarns with matrix material, weaving the yarn into fabric to produce a continuous fabric supply, and feeding multiple layers of net-shaped fabrics having optimally oriented fibers into a debulking tool to form an undebulked preform. The continuous press forming fabrication process includes partially debulking the preform, cutting the partially debulked preform, and debulking the partially debulked preform to form a netshape. An electron-beam or similar technique then cures the structure. The pultrusion fabric process includes feeding the undebulked preform into a heated die and gradually debulking the undebulked preform. The undebulked preform in the heated die changes dimension until a desired cross-sectional dimension is achieved. This process further includes obtaining a net-shaped infiltrated uncured preform, cutting the uncured preform to a desired length, and electron-beam curing (or similar technique) the uncured preform. These fabrication methods produce superior structures formed at higher production rates, resulting in lower cost and high structural performance.

  11. Design of specially adapted reactive coordinates to economically compute potential and kinetic energy operators including geometry relaxation

    NASA Astrophysics Data System (ADS)

    Thallmair, Sebastian; Roos, Matthias K.; de Vivie-Riedle, Regina

    2016-06-01

    Quantum dynamics simulations require prior knowledge of the potential energy surface as well as the kinetic energy operator. Typically, they are evaluated in a low-dimensional subspace of the full configuration space of the molecule as its dimensionality increases proportional to the number of atoms. This entails the challenge to find the most suitable subspace. We present an approach to design specially adapted reactive coordinates spanning this subspace. In addition to the essential geometric changes, these coordinates take into account the relaxation of the non-reactive coordinates without the necessity of performing geometry optimizations at each grid point. The method is demonstrated for an ultrafast photoinduced bond cleavage in a commonly used organic precursor for the generation of electrophiles. The potential energy surfaces for the reaction as well as the Wilson G-matrix as part of the kinetic energy operator are shown for a complex chemical reaction, both including the relaxation of the non-reactive coordinates on equal footing. A microscopic interpretation of the shape of the G-matrix elements allows to analyze the impact of the non-reactive coordinates on the kinetic energy operator. Additionally, we compare quantum dynamics simulations with and without the relaxation of the non-reactive coordinates included in the kinetic energy operator to demonstrate its influence.

  12. Design of specially adapted reactive coordinates to economically compute potential and kinetic energy operators including geometry relaxation.

    PubMed

    Thallmair, Sebastian; Roos, Matthias K; de Vivie-Riedle, Regina

    2016-06-21

    Quantum dynamics simulations require prior knowledge of the potential energy surface as well as the kinetic energy operator. Typically, they are evaluated in a low-dimensional subspace of the full configuration space of the molecule as its dimensionality increases proportional to the number of atoms. This entails the challenge to find the most suitable subspace. We present an approach to design specially adapted reactive coordinates spanning this subspace. In addition to the essential geometric changes, these coordinates take into account the relaxation of the non-reactive coordinates without the necessity of performing geometry optimizations at each grid point. The method is demonstrated for an ultrafast photoinduced bond cleavage in a commonly used organic precursor for the generation of electrophiles. The potential energy surfaces for the reaction as well as the Wilson G-matrix as part of the kinetic energy operator are shown for a complex chemical reaction, both including the relaxation of the non-reactive coordinates on equal footing. A microscopic interpretation of the shape of the G-matrix elements allows to analyze the impact of the non-reactive coordinates on the kinetic energy operator. Additionally, we compare quantum dynamics simulations with and without the relaxation of the non-reactive coordinates included in the kinetic energy operator to demonstrate its influence.

  13. Adaptive Signal Processing Testbed application software: User's manual

    NASA Astrophysics Data System (ADS)

    Parliament, Hugh A.

    1992-05-01

    The Adaptive Signal Processing Testbed (ASPT) application software is a set of programs that provide general data acquisition and minimal processing functions on live digital data. The data are obtained from a digital input interface whose data source is the DAR4000 digital quadrature receiver that receives a phase shift keying signal at 21.4 MHz intermediate frequency. The data acquisition software is used to acquire raw unprocessed data from the DAR4000 and store it on disk in the Sun workstation based ASPT. File processing utilities are available to convert the stored files for analysis. The data evaluation software is used for the following functions: acquisition of data from the DAR4000, conversion to IEEE format, and storage to disk; acquisition of data from the DAR4000, power spectrum estimation, and on-line plotting on the graphics screen; and processing of disk file data, power spectrum estimation, and display and/or storage to disk in the new format. A user's guide is provided that describes the acquisition and evaluation programs along with how to acquire, evaluate, and use the data.

  14. Factors associated with the process of adaptation among Pakistani adolescent females living in United States.

    PubMed

    Khuwaja, Salma A; Selwyn, Beatrice J; Mgbere, Osaro; Khuwaja, Alam; Kapadia, Asha; McCurdy, Sheryl; Hsu, Chiehwen E

    2013-04-01

    This study explored post-migration experiences of recently migrated Pakistani Muslim adolescent females residing in the United States. In-depth, semi-structured interviews were conducted with thirty Pakistani Muslim adolescent females between the ages of 15 and 18 years living with their families in Houston, Texas. Data obtained from the interviews were evaluated using discourse analysis to identify major reoccurring themes. Participants discussed factors associated with the process of adaptation to the American culture. The results revealed that the main factors associated with adaptation process included positive motivation for migration, family bonding, social support networks, inter-familial communication, aspiration of adolescents to learn other cultures, availability of English-as-second-language programs, participation in community rebuilding activities, and faith practices, English proficiency, peer pressure, and inter-generational conflicts. This study provided much needed information on factors associated with adaptation process of Pakistani Muslim adolescent females in the United States. The results have important implications for improving the adaptation process of this group and offer potential directions for intervention and counseling services.

  15. Including hydrological self-regulating processes in peatland models: Effects on peatmoss drought projections.

    PubMed

    Nijp, Jelmer J; Metselaar, Klaas; Limpens, Juul; Teutschbein, Claudia; Peichl, Matthias; Nilsson, Mats B; Berendse, Frank; van der Zee, Sjoerd E A T M

    2017-02-15

    The water content of the topsoil is one of the key factors controlling biogeochemical processes, greenhouse gas emissions and biosphere - atmosphere interactions in many ecosystems, particularly in northern peatlands. In these wetland ecosystems, the water content of the photosynthetic active peatmoss layer is crucial for ecosystem functioning and carbon sequestration, and is sensitive to future shifts in rainfall and drought characteristics. Current peatland models differ in the degree in which hydrological feedbacks are included, but how this affects peatmoss drought projections is unknown. The aim of this paper was to systematically test whether the level of hydrological detail in models could bias projections of water content and drought stress for peatmoss in northern peatlands using downscaled projections for rainfall and potential evapotranspiration in the current (1991-2020) and future climate (2061-2090). We considered four model variants that either include or exclude moss (rain)water storage and peat volume change, as these are two central processes in the hydrological self-regulation of peatmoss carpets. Model performance was validated using field data of a peatland in northern Sweden. Including moss water storage as well as peat volume change resulted in a significant improvement of model performance, despite the extra parameters added. The best performance was achieved if both processes were included. Including moss water storage and peat volume change consistently reduced projected peatmoss drought frequency with >50%, relative to the model excluding both processes. Projected peatmoss drought frequency in the growing season was 17% smaller under future climate than current climate, but was unaffected by including the hydrological self-regulating processes. Our results suggest that ignoring these two fine-scale processes important in hydrological self-regulation of northern peatlands will have large consequences for projected climate change impact on

  16. Some Aspects of Visual Processing Under Chromatic Adaptation.

    NASA Astrophysics Data System (ADS)

    Wilson, Julie Ann Frances

    Available from UMI in association with The British Library. This thesis describes the results of experimental investigations into three types of visual processing, namely, displacement thresholds for motion detection, speed and motion detection, and rod-cone interaction effects. Each of these topics is described separately. The overall conclusions and summary of this work with an emphasis on chromatic processes are presented in the last chapter. The introductory chapter of the thesis deals mostly with the anatomical and theoretical aspects of vision and the development of a system for the standardization of colour. Equations for the CIE colour and colour difference specifications are described. Equipment, optical apparatus and general calibration procedures for all the investigations are covered in Chapter Two. Displacement thresholds for motion detection under conditions of chromatic adaptation are the subject of Chapter Three. The smallest, continuous target displacement sufficient to cause a sensation of movement was measured under conditions of chromatic adaptation. The experiments were carried out for test target and background field wavelengths which selectively isolated the activity of the colour mechanisms of the human eye. In Chapter Four, two mechanisms capable of speed discrimination and motion detection are proposed. Experimental data are reported which suggest that the visual system employs both schemes. A small circular target of high retinal illuminance level can have a comet-like appearance when presented moving continuously with a speed as low as 0.2 deg/s. Data on the parametric properties of the 'comet effect' are presented in Chapter Five. Measurement of the target spectral irradiance levels sufficient to yield the 'comet effect' suggests that the lengthening of the circular target reflects a rod-cone interaction and therefore it may be due to unsuppressed, saturated rod responses at high retinal illuminance levels. Computational methods are

  17. On the stability of adaptation process in active noise control systems.

    PubMed

    Ardekani, Iman Tabatabaei; Abdulla, Waleed H

    2011-01-01

    The stability analysis of the adaptation process, performed by the filtered-x least mean square algorithm on weights of active noise controllers, has not been fully investigated. The main contribution of this paper is conducting a theoretical stability analysis for this process without utilizing commonly used simplifying assumptions regarding the secondary electro-acoustic channel. The core of this analysis is based on the root locus theory. The general rules for constructing the root locus plot of the adaptation process are derived by obtaining root locus parameters, including start points, end points, asymptote lines, and breakaway points. The conducted analysis leads to the derivation of a general upper-bound for the adaptation step-size beyond which the mean weight vector of the active noise controller becomes unstable. Also, this analysis yields the optimum step-size for which the adaptive active noise controller has its fastest dynamic performance. The proposed upper-bound and optimum values apply to general secondary electro-acoustic channels, unlike the commonly used ones which apply to only pure delay channels. The results are found to agree very well with those obtained from numerical analyses and computer simulation experiments.

  18. Indoor human thermal adaptation: dynamic processes and weighting factors.

    PubMed

    Luo, M; Cao, B; Ouyang, Q; Zhu, Y

    2017-03-01

    In this study, we explore the correlations between indoor climate change and human thermal adaptation, especially with regard to the timescale and weighting factors of physiological adaptation. A comparative experiment was conducted in China where wintertime indoor climate in the southern region (devoid of space heating) is much colder than in the northern region (with pervasive district heating). Four subject groups with different indoor thermal experiences participated in this climate chamber experiment. The results indicate that previous indoor thermal exposure is an important contributor to occupants' physiological adaptation. More specifically, subjects acclimated to neutral-warm indoors tended to have stronger physiological responses and felt more uncomfortable in moderate cold exposures than those adapted to the cold. As for the driving force of thermal adaptation, physiological acclimation is an important aspect among all the supposed adaptive layers. However, the physiological adaptation speed lags behind changes in the overall subjective perception.

  19. Spacecraft materials guide. [including: encapsulants and conformal coatings; optical materials; lubrication; and, bonding and joining processes

    NASA Technical Reports Server (NTRS)

    Staugaitis, C. L. (Editor)

    1975-01-01

    Materials which have demonstrated their suitability for space application are summarized. Common, recurring problems in encapsulants and conformal coatings, optical materials, lubrication, and bonding and joining are noted. The subjects discussed include: low density and syntactic foams, electrical encapsulants; optical glasses, interference filter, mirrors; oils, greases, lamillar lubricants; and, soldering and brazing processes.

  20. 25 CFR 42.7 - What does due process in a formal disciplinary proceeding include?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... disciplinary action, except under the following circumstances: (1) If the Act requires immediate removal (such... 25 Indians 1 2011-04-01 2011-04-01 false What does due process in a formal disciplinary proceeding include? 42.7 Section 42.7 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION...

  1. 25 CFR 42.7 - What does due process in a formal disciplinary proceeding include?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... disciplinary action, except under the following circumstances: (1) If the Act requires immediate removal (such... 25 Indians 1 2014-04-01 2014-04-01 false What does due process in a formal disciplinary proceeding include? 42.7 Section 42.7 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION...

  2. 25 CFR 42.7 - What does due process in a formal disciplinary proceeding include?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... disciplinary action, except under the following circumstances: (1) If the Act requires immediate removal (such... 25 Indians 1 2013-04-01 2013-04-01 false What does due process in a formal disciplinary proceeding include? 42.7 Section 42.7 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION...

  3. 25 CFR 42.7 - What does due process in a formal disciplinary proceeding include?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... disciplinary action, except under the following circumstances: (1) If the Act requires immediate removal (such... 25 Indians 1 2010-04-01 2010-04-01 false What does due process in a formal disciplinary proceeding include? 42.7 Section 42.7 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION...

  4. 25 CFR 42.7 - What does due process in a formal disciplinary proceeding include?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... disciplinary action, except under the following circumstances: (1) If the Act requires immediate removal (such... 25 Indians 1 2012-04-01 2011-04-01 true What does due process in a formal disciplinary proceeding include? 42.7 Section 42.7 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION...

  5. Adaptive Memory: Evaluating Alternative Forms of Fitness-Relevant Processing in the Survival Processing Paradigm

    PubMed Central

    Sandry, Joshua; Trafimow, David; Marks, Michael J.; Rice, Stephen

    2013-01-01

    Memory may have evolved to preserve information processed in terms of its fitness-relevance. Based on the assumption that the human mind comprises different fitness-relevant adaptive mechanisms contributing to survival and reproductive success, we compared alternative fitness-relevant processing scenarios with survival processing. Participants rated words for relevancy to fitness-relevant and control conditions followed by a delay and surprise recall test (Experiment 1a). Participants recalled more words processed for their relevance to a survival situation. We replicated these findings in an online study (Experiment 2) and a study using revised fitness-relevant scenarios (Experiment 3). Across all experiments, we did not find a mnemonic benefit for alternative fitness-relevant processing scenarios, questioning assumptions associated with an evolutionary account of remembering. Based on these results, fitness-relevance seems to be too wide-ranging of a construct to account for the memory findings associated with survival processing. We propose that memory may be hierarchically sensitive to fitness-relevant processing instructions. We encourage future researchers to investigate the underlying mechanisms responsible for survival processing effects and work toward developing a taxonomy of adaptive memory. PMID:23585858

  6. [EMDR and adaptive information processing. Psychotherapy as a stimulation of the self-reparative psychological processes].

    PubMed

    Fernandez, Isabel; Giovannozzi, Gabriella

    2012-01-01

    Based on the concept of traumatic event, the model of the adaptive information processing is described to illustrate how EMDR is applied to reprocess the trauma and resolve post-traumatic psychopathology. The eight phases of the EMDR treatment are presented together with the way an EMDR session is conducted and the contribution and innovation that EMDR represents in the field of therapy of post-traumatic states and its applicability in other symptomatic conditions.< span class="text23">

  7. Planar optical waveguide based sandwich assay sensors and processes for the detection of biological targets including early detection of cancers

    DOEpatents

    Martinez, Jennifer S.; Swanson, Basil I.; Shively, John E.; Li, Lin

    2009-06-02

    An assay element is described including recognition ligands adapted for binding to carcinoembryonic antigen (CEA) bound to a film on a single mode planar optical waveguide, the film from the group of a membrane, a polymerized bilayer membrane, and a self-assembled monolayer containing polyethylene glycol or polypropylene glycol groups therein and an assay process for detecting the presence of CEA is described including injecting a possible CEA-containing sample into a sensor cell including the assay element, maintaining the sample within the sensor cell for time sufficient for binding to occur between CEA present within the sample and the recognition ligands, injecting a solution including a reporter ligand into the sensor cell; and, interrogating the sample within the sensor cell with excitation light from the waveguide, the excitation light provided by an evanescent field of the single mode penetrating into the biological target-containing sample to a distance of less than about 200 nanometers from the waveguide thereby exciting any bound reporter ligand within a distance of less than about 200 nanometers from the waveguide and resulting in a detectable signal.

  8. Parallel Block Structured Adaptive Mesh Refinement on Graphics Processing Units

    SciTech Connect

    Beckingsale, D. A.; Gaudin, W. P.; Hornung, R. D.; Gunney, B. T.; Gamblin, T.; Herdman, J. A.; Jarvis, S. A.

    2014-11-17

    Block-structured adaptive mesh refinement is a technique that can be used when solving partial differential equations to reduce the number of zones necessary to achieve the required accuracy in areas of interest. These areas (shock fronts, material interfaces, etc.) are recursively covered with finer mesh patches that are grouped into a hierarchy of refinement levels. Despite the potential for large savings in computational requirements and memory usage without a corresponding reduction in accuracy, AMR adds overhead in managing the mesh hierarchy, adding complex communication and data movement requirements to a simulation. In this paper, we describe the design and implementation of a native GPU-based AMR library, including: the classes used to manage data on a mesh patch, the routines used for transferring data between GPUs on different nodes, and the data-parallel operators developed to coarsen and refine mesh data. We validate the performance and accuracy of our implementation using three test problems and two architectures: an eight-node cluster, and over four thousand nodes of Oak Ridge National Laboratory’s Titan supercomputer. Our GPU-based AMR hydrodynamics code performs up to 4.87× faster than the CPU-based implementation, and has been scaled to over four thousand GPUs using a combination of MPI and CUDA.

  9. Adaptation of swallowing hyo-laryngeal kinematics is distinct in oral vs. pharyngeal sensory processing

    PubMed Central

    Lokhande, Akshay; Christopherson, Heather; German, Rebecca; Stone, Alice

    2012-01-01

    Before a bolus is pushed into the pharynx, oral sensory processing is critical for planning movements of the subsequent pharyngeal swallow, including hyoid bone and laryngeal (hyo-laryngeal) kinematics. However, oral and pharyngeal sensory processing for hyo-laryngeal kinematics is not fully understood. In 11 healthy adults, we examined changes in kinematics with sensory adaptation, sensitivity shifting, with oropharyngeal swallows vs. pharyngeal swallows (no oral processing), and with various bolus volumes and tastes. Only pharyngeal swallows showed sensory adaptation (gradual changes in kinematics with repeated exposure to the same bolus). Conversely, only oropharyngeal swallows distinguished volume differences, whereas pharyngeal swallows did not. No taste effects were observed for either swallow type. The hyo-laryngeal kinematics were very similar between oropharyngeal swallows and pharyngeal swallows with a comparable bolus. Sensitivity shifting (changing sensory threshold for a small bolus when it immediately follows several very large boluses) was not observed in pharyngeal or oropharyngeal swallowing. These findings indicate that once oral sensory processing has set a motor program for a specific kind of bolus (i.e., 5 ml water), hyo-laryngeal movements are already highly standardized and optimized, showing no shifting or adaptation regardless of repeated exposure (sensory adaptation) or previous sensory experiences (sensitivity shifting). Also, the oral cavity is highly specialized for differentiating certain properties of a bolus (volume) that might require a specific motor plan to ensure swallowing safety, whereas the pharyngeal cavity does not make the same distinctions. Pharyngeal sensory processing might not be able to adjust motor plans created by the oral cavity once the swallow has already been triggered. PMID:22403349

  10. A comparison study between Wiener and adaptive state estimation (STAP-ASE) algorithms for space time adaptive radar processing

    NASA Astrophysics Data System (ADS)

    Malek, Obaidul; Venetsanopoulos, Anastasios; Anpalagan, Alagan

    2010-08-01

    Space Time Adaptive Processing (STAP) is a multi-dimensional adaptive signal processing technique, which processes the signal in spatial and Doppler domains for which a target detection hypothesis is to be formed. It is a sample based technique and based on the assumption of adequate number of Independent and Identically Distributed (i.i.d.) training data set in the surrounding environment. The principal challenge of the radar processing lies when it violates these underlying assumptions due to severe dynamic heterogeneous clutter (hot clutter) and jammer effects. This in turn degrades the Signal to Interference-plus-Noise Ratio (SINR), hence signal detection performance. Classical Wiener filtering theory is inadequate to deal with nonlinear and nonstationary interferences, however Wiener filtering approach is optimal for stationary and linear systems. But, these challenges can be overcome by Adaptive Sequential State Estimation (ASSE) filtering technique.

  11. Consortium for Adaptive Optics and Image Post-Processing

    DTIC Science & Technology

    2008-06-12

    optics bench laboratory is located in Kula , Maui, and is called “The Space Surveillance Simulator” (S-Cube). S-Cube is designed to simulate both the...Wheeler, Trex Maui Personnel from the Center for Adaptive Optics Contributed DURIP Maui Adaptive Optics Laboratory (S-Cube), Kula Setup Meeting (26...for Astronomy’s buildings in Kula , Maui. The move also caused a change in the scientists directly involved in the simulator as well as a change in

  12. Process for treating spent catalyst including antimony halides from chlorofluorocarbon production

    SciTech Connect

    Kalcevic, V.; McGahan, J.F.

    1988-06-14

    A process for treating spent catalyst from chlorofluorocarbon production is described wherein the catalyst includes antimony halides and undergoes hydrolysis in an aqueous medium to produce insoluble antimony compounds and fluoride ions. The process comprises hydrolyzing the catalyst in an aqueous solution of ferric chloride having a sufficient concentration of ferric ions to complex substantially all of the fluoride ions produced upon hydrolysis of the catalyst, neutralizing the reaction mass present following hydrolysis of the catalyst and complexing of the fluoride ions by contacting the reaction mass with an aqueous suspension of a compound selected from the class consisting of calcium hydroxide and magnesium hydroxide, and separating the insoluble antimony compounds from the neutralized reaction mass.

  13. A high liquid yield process for retorting various organic materials including oil shale

    DOEpatents

    Coburn, T.T.

    1988-07-26

    This invention is a continuous retorting process for various high molecular weight organic materials, including oil shale, that yields an enhanced output of liquid product. The organic material, mineral matter, and an acidic catalyst, that appreciably adsorbs alkenes on surface sites at prescribed temperatures, are mixed and introduced into a pyrolyzer. A circulating stream of olefin enriched pyrolysis gas is continuously swept through the organic material and catalyst, whereupon, as the result of pyrolysis, the enhanced liquid product output is provided. Mixed spent organic material, mineral matter, and cool catalyst are continuously withdrawn from the pyrolyzer. Combustion of the spent organic material and mineral matter serves to reheat the catalyst. Olefin depleted pyrolysis gas, from the pyrolyzer, is enriched in olefins and recycled into the pyrolyzer. The reheated acidic catalyst is separated from the mineral matter and again mixed with fresh organic material, to maintain the continuously cyclic process. 2 figs.

  14. High liquid yield process for retorting various organic materials including oil shale

    DOEpatents

    Coburn, Thomas T.

    1990-01-01

    This invention is a continuous retorting process for various high molecular weight organic materials, including oil shale, that yields an enhanced output of liquid product. The organic material, mineral matter, and an acidic catalyst, that appreciably adsorbs alkenes on surface sites at prescribed temperatures, are mixed and introduced into a pyrolyzer. A circulating stream of olefin enriched pyrolysis gas is continuously swept through the organic material and catalyst, whereupon, as the result of pyrolysis, the enhanced liquid product output is provided. Mixed spent organic material, mineral matter, and cool catalyst are continuously withdrawn from the pyrolyzer. Combustion of the spent organic material and mineral matter serves to reheat the catalyst. Olefin depleted pyrolysis gas, from the pyrolyzer, is enriched in olefins and recycled into the pyrolyzer. The reheated acidic catalyst is separated from the mineral matter and again mixed with fresh organic material, to maintain the continuously cyclic process.

  15. Instructions included? Make safety training part of medical device procurement process.

    PubMed

    Keller, James P

    2010-04-01

    Before hospitals embrace new technologies, it's important that medical personnel agree on how best to use them. Likewise, hospitals must provide the support to operate these sophisticated devices safely. With this in mind, it's wise for hospitals to include medical device training in the procurement process. Moreover, purchasing professionals can play a key role in helping to increase the amount of user training for medical devices and systems. What steps should you take to help ensure that new medical devices are implemented safely? Here are some tips.

  16. Non-orthogonal spin-adaptation of coupled cluster methods: A new implementation of methods including quadruple excitations

    SciTech Connect

    Matthews, Devin A.; Stanton, John F.

    2015-02-14

    The theory of non-orthogonal spin-adaptation for closed-shell molecular systems is applied to coupled cluster methods with quadruple excitations (CCSDTQ). Calculations at this level of detail are of critical importance in describing the properties of molecular systems to an accuracy which can meet or exceed modern experimental techniques. Such calculations are of significant (and growing) importance in such fields as thermodynamics, kinetics, and atomic and molecular spectroscopies. With respect to the implementation of CCSDTQ and related methods, we show that there are significant advantages to non-orthogonal spin-adaption with respect to simplification and factorization of the working equations and to creating an efficient implementation. The resulting algorithm is implemented in the CFOUR program suite for CCSDT, CCSDTQ, and various approximate methods (CCSD(T), CC3, CCSDT-n, and CCSDT(Q))

  17. Non-orthogonal spin-adaptation of coupled cluster methods: A new implementation of methods including quadruple excitations.

    PubMed

    Matthews, Devin A; Stanton, John F

    2015-02-14

    The theory of non-orthogonal spin-adaptation for closed-shell molecular systems is applied to coupled cluster methods with quadruple excitations (CCSDTQ). Calculations at this level of detail are of critical importance in describing the properties of molecular systems to an accuracy which can meet or exceed modern experimental techniques. Such calculations are of significant (and growing) importance in such fields as thermodynamics, kinetics, and atomic and molecular spectroscopies. With respect to the implementation of CCSDTQ and related methods, we show that there are significant advantages to non-orthogonal spin-adaption with respect to simplification and factorization of the working equations and to creating an efficient implementation. The resulting algorithm is implemented in the CFOUR program suite for CCSDT, CCSDTQ, and various approximate methods (CCSD(T), CC3, CCSDT-n, and CCSDT(Q)).

  18. Non-orthogonal spin-adaptation of coupled cluster methods: A new implementation of methods including quadruple excitations

    NASA Astrophysics Data System (ADS)

    Matthews, Devin A.; Stanton, John F.

    2015-02-01

    The theory of non-orthogonal spin-adaptation for closed-shell molecular systems is applied to coupled cluster methods with quadruple excitations (CCSDTQ). Calculations at this level of detail are of critical importance in describing the properties of molecular systems to an accuracy which can meet or exceed modern experimental techniques. Such calculations are of significant (and growing) importance in such fields as thermodynamics, kinetics, and atomic and molecular spectroscopies. With respect to the implementation of CCSDTQ and related methods, we show that there are significant advantages to non-orthogonal spin-adaption with respect to simplification and factorization of the working equations and to creating an efficient implementation. The resulting algorithm is implemented in the CFOUR program suite for CCSDT, CCSDTQ, and various approximate methods (CCSD(T), CC3, CCSDT-n, and CCSDT(Q)).

  19. The Contextualized Technology Adaptation Process (CTAP): Optimizing Health Information Technology to Improve Mental Health Systems.

    PubMed

    Lyon, Aaron R; Wasse, Jessica Knaster; Ludwig, Kristy; Zachry, Mark; Bruns, Eric J; Unützer, Jürgen; McCauley, Elizabeth

    2016-05-01

    Health information technologies have become a central fixture in the mental healthcare landscape, but few frameworks exist to guide their adaptation to novel settings. This paper introduces the contextualized technology adaptation process (CTAP) and presents data collected during Phase 1 of its application to measurement feedback system development in school mental health. The CTAP is built on models of human-centered design and implementation science and incorporates repeated mixed methods assessments to guide the design of technologies to ensure high compatibility with a destination setting. CTAP phases include: (1) Contextual evaluation, (2) Evaluation of the unadapted technology, (3) Trialing and evaluation of the adapted technology, (4) Refinement and larger-scale implementation, and (5) Sustainment through ongoing evaluation and system revision. Qualitative findings from school-based practitioner focus groups are presented, which provided information for CTAP Phase 1, contextual evaluation, surrounding education sector clinicians' workflows, types of technologies currently available, and influences on technology use. Discussion focuses on how findings will inform subsequent CTAP phases, as well as their implications for future technology adaptation across content domains and service sectors.

  20. The adaptational strategies of the hindlimb muscles in the Tenrecidae species including the aquatic web-footed tenrec (Limnogale mergulus).

    PubMed

    Endo, Hideki; Yonezawa, Takahiro; Rakotondraparany, Felix; Sasaki, Motoki; Hasegawa, Masami

    2006-07-01

    The hindlimb muscles in four species of Tenrecidae (Oryzoryctinae: Talazac long-tailed tenrec and web-footed tenrec, Tenrecinae: lesser hedgehog tenrec, and streaked tenrec), were examined macroscopically. The weight ratios of the muscles to the body in the oryzoryctinid species are larger than those in Tenrecinae, since the Oryzoryctinae species have an obviously smaller body from the evolutionary point of view. It can be primarily pointed out that the adaptation of the body size is different between the two subfamilies, and secondarily, that functional adaptation to locomotion is complete within each subfamily. The weight data and the morphological findings demonstrate that the web-footed tenrec possesses an extraordinary large M. semimembranosus in comparison to the Talazac long-tailed tenrec in their weight ratios. This muscle may act as a strong flexor motor in the knee joint during the aquatic locomotion of the web-footed tenrec. Since the other muscles of the web-footed tenrec are similar to those of the Talazac long-tailed tenrec regards weight ratio data, we think that the web-footed tenrec may have derived from a terrestrial ancestor such as the long-tailed tenrecs. In Tenrecinae the streaked tenrec is equipped with larger Mm. adductores, M. semimembranosus and M. triceps surae than the lesser hedgehog tenrec. This species is adapted to fossorial life derived from non-specialized ancestors within the evolutionary lines of the spiny tenrecs.

  1. Time in Redox Adaptation Processes: From Evolution to Hormesis

    PubMed Central

    Sthijns, Mireille M. J. P. E.; Weseler, Antje R.; Bast, Aalt; Haenen, Guido R. M. M.

    2016-01-01

    Life on Earth has to adapt to the ever changing environment. For example, due to introduction of oxygen in the atmosphere, an antioxidant network evolved to cope with the exposure to oxygen. The adaptive mechanisms of the antioxidant network, specifically the glutathione (GSH) system, are reviewed with a special focus on the time. The quickest adaptive response to oxidative stress is direct enzyme modification, increasing the GSH levels or activating the GSH-dependent protective enzymes. After several hours, a hormetic response is seen at the transcriptional level by up-regulating Nrf2-mediated expression of enzymes involved in GSH synthesis. In the long run, adaptations occur at the epigenetic and genomic level; for example, the ability to synthesize GSH by phototrophic bacteria. Apparently, in an adaptive hormetic response not only the dose or the compound, but also time, should be considered. This is essential for targeted interventions aimed to prevent diseases by successfully coping with changes in the environment e.g., oxidative stress. PMID:27690013

  2. Absence of rapid sensory adaptation in neocortex during information processing states.

    PubMed

    Castro-Alamancos, Manuel A

    2004-02-05

    One prominent feature of sensory responses in neocortex is that they rapidly adapt to increases in frequency, a process called "sensory adaptation." Here we show that sensory adaptation mainly occurs during quiescent states such as anesthesia, slow-wave sleep, and awake immobility. In contrast, during behavior-ally activated states, sensory responses are already adapted. For instance, during learning of a behavioral task, when an animal is very alert and expectant, sensory adaptation is mostly absent. After learning occurs, and the task becomes routine, the level of alertness lessens and sensory adaptation becomes robust. The primary sensory thalamocortical pathway of alert and expectant animals is in the adapted state, which may be required for adequate sensory information processing.

  3. Adaptability and the integration of computer-based information processing into the dynamics of organizations.

    PubMed

    Kampfner, Roberto R

    2006-07-01

    The structure of a system influences its adaptability. An important result of adaptability theory is that subsystem independence increases adaptability [Conrad, M., 1983. Adaptability. Plenum Press, New York]. Adaptability is essential in systems that face an uncertain environment such as biological systems and organizations. Modern organizations are the product of human design. And so it is their structure and the effect that it has on their adaptability. In this paper we explore the potential effects of computer-based information processing on the adaptability of organizations. The integration of computer-based processes into the dynamics of the functions they support and the effect it has on subsystem independence are especially relevant to our analysis.

  4. ADAPT: building conceptual models of the physical and biological processes across permafrost landscapes

    NASA Astrophysics Data System (ADS)

    Allard, M.; Vincent, W. F.; Lemay, M.

    2012-12-01

    Fundamental and applied permafrost research is called upon in Canada in support of environmental protection, economic development and for contributing to the international efforts in understanding climatic and ecological feedbacks of permafrost thawing under a warming climate. The five year "Arctic Development and Adaptation to Permafrost in Transition" program (ADAPT) funded by NSERC brings together 14 scientists from 10 Canadian universities and involves numerous collaborators from academia, territorial and provincial governments, Inuit communities and industry. The geographical coverage of the program encompasses all of the permafrost regions of Canada. Field research at a series of sites across the country is being coordinated. A common protocol for measuring ground thermal and moisture regime, characterizing terrain conditions (vegetation, topography, surface water regime and soil organic matter contents) is being applied in order to provide inputs for designing a general model to provide an understanding of transfers of energy and matter in permafrost terrain, and the implications for biological and human systems. The ADAPT mission is to produce an 'Integrated Permafrost Systems Science' framework that will be used to help generate sustainable development and adaptation strategies for the North in the context of rapid socio-economic and climate change. ADAPT has three major objectives: to examine how changing precipitation and warming temperatures affect permafrost geosystems and ecosystems, specifically by testing hypotheses concerning the influence of the snowpack, the effects of water as a conveyor of heat, sediments, and carbon in warming permafrost terrain and the processes of permafrost decay; to interact directly with Inuit communities, the public sector and the private sector for development and adaptation to changes in permafrost environments; and to train the new generation of experts and scientists in this critical domain of research in Canada

  5. Digital adaptive coronagraphy using SLMs: promising prospects of a novel approach, including high-contrast imaging of multiple stars systems

    NASA Astrophysics Data System (ADS)

    Kühn, Jonas; Patapis, Polychronis

    2016-07-01

    We introduce a new technological framework for high-contrast coronagraphy, namely digital adaptive coronagraphy (DAC) using spatial light modulators (SLMs), taking advantage of recent advances in this technology. We present proof-of-principle experimental results in the visible, using a transmissive twisted nematic liquid crystal SLM display to show that SLMs can be successfully implemented as focal-plane phase-mask coronagraphs (4QPM, 8OPM,...), and that the technology is essentially in place to address realistic instrumental configurations. We explore a specific application where SLM-based adaptive coronagraphy might be particularly competitive, which is direct imaging of multiple stars systems, by simultaneously nulling multiple point sources in the field. Using a simple approach to compute a brightness-weighted synthetized coronagraphic phase map, we show that in the case of binaries the contrast gain over using a regular phase map can exceed 4 stellar magnitudes for a 1:1 binaries down to separation as close as 1 λ/D. Thanks to video-rate update frequency of the SLM, the technique is in principle compatible with sky rotation in the case of altitude-azimuth telescope mounts, and can address multiple target configurations with no actual mechanical or hardware change.

  6. Parameterization of the photochemistry of stratospheric ozone including catalytic loss processes

    NASA Technical Reports Server (NTRS)

    Stolarski, R. S.; Douglass, A. R.

    1985-01-01

    A parameterization has been developed which accurately describes the photochemical response of odd oxygen to dynamically induced perturbations in odd oxygen and temperature. The temperature and odd oxygen dependencies of the loss processes for odd oxygen through catalytic cycles involving odd nitrogen, odd chlorine, and odd hydrogen have been specifically included. The assumption that a linear perturbation equation may be used to describe the response of odd oxygen to perturbations in odd oxygen and temperature has been tested and found to be acceptable for a physically reasonable range of perturbations, i.e., up to approximately 50 percent in odd oxygen mixing ratio and approximately 10 K in temperature. The scheme should prove useful for analyzing the feedback between ozone chemistry and ozone transport and also for analysis of ozone and temperature data.

  7. Regional and Foreign Accent Processing in English: Can Listeners Adapt?

    ERIC Educational Resources Information Center

    Floccia, Caroline; Butler, Joseph; Goslin, Jeremy; Ellis, Lucy

    2009-01-01

    Recent data suggest that the first presentation of a foreign accent triggers a delay in word identification, followed by a subsequent adaptation. This study examines under what conditions the delay resumes to baseline level. The delay will be experimentally induced by the presentation of sentences spoken to listeners in a foreign or a regional…

  8. The role of the microprocessor in onboard image processing for the information adaptive system

    NASA Technical Reports Server (NTRS)

    Kelly, W. L., IV; Meredith, B. D.

    1980-01-01

    The preliminary design of the Information Adaptive System is presented. The role of the microprocessor in the implementation of the individual processing elements is discussed. Particular emphasis is placed on multispectral image data processing.

  9. Evolutionary adaptations for the temporal processing of natural sounds by the anuran peripheral auditory system

    PubMed Central

    Schrode, Katrina M.; Bee, Mark A.

    2015-01-01

    ABSTRACT Sensory systems function most efficiently when processing natural stimuli, such as vocalizations, and it is thought that this reflects evolutionary adaptation. Among the best-described examples of evolutionary adaptation in the auditory system are the frequent matches between spectral tuning in both the peripheral and central auditory systems of anurans (frogs and toads) and the frequency spectra of conspecific calls. Tuning to the temporal properties of conspecific calls is less well established, and in anurans has so far been documented only in the central auditory system. Using auditory-evoked potentials, we asked whether there are species-specific or sex-specific adaptations of the auditory systems of gray treefrogs (Hyla chrysoscelis) and green treefrogs (H. cinerea) to the temporal modulations present in conspecific calls. Modulation rate transfer functions (MRTFs) constructed from auditory steady-state responses revealed that each species was more sensitive than the other to the modulation rates typical of conspecific advertisement calls. In addition, auditory brainstem responses (ABRs) to paired clicks indicated relatively better temporal resolution in green treefrogs, which could represent an adaptation to the faster modulation rates present in the calls of this species. MRTFs and recovery of ABRs to paired clicks were generally similar between the sexes, and we found no evidence that males were more sensitive than females to the temporal modulation patterns characteristic of the aggressive calls used in male–male competition. Together, our results suggest that efficient processing of the temporal properties of behaviorally relevant sounds begins at potentially very early stages of the anuran auditory system that include the periphery. PMID:25617467

  10. Flight data processing with the F-8 adaptive algorithm

    NASA Technical Reports Server (NTRS)

    Hartmann, G.; Stein, G.; Petersen, K.

    1977-01-01

    An explicit adaptive control algorithm based on maximum likelihood estimation of parameters has been designed for NASA's DFBW F-8 aircraft. To avoid iterative calculations, the algorithm uses parallel channels of Kalman filters operating at fixed locations in parameter space. This algorithm has been implemented in NASA/DFRC's Remotely Augmented Vehicle (RAV) facility. Real-time sensor outputs (rate gyro, accelerometer and surface position) are telemetered to a ground computer which sends new gain values to an on-board system. Ground test data and flight records were used to establish design values of noise statistics and to verify the ground-based adaptive software. The software and its performance evaluation based on flight data are described

  11. Linking Man and Machine Through Adaptive Sensory Processing

    DTIC Science & Technology

    2014-06-02

    Odelia Schwartz 5e. TASK NUMBER 5f WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAMES AND ADDRESSES 8, PERFORMING ORGANIZATION REPORT Albert ... Einstein College of Medicine of Y esl NUMBER 1300 Morris Park A venue Bronx, NY 10461 -1900 9. SPONSORING;MONITORING AGENCY NAME(S) AND ADDRESS 10...PhD program at Einstein . Her work has now been published in the Journal of Vision (Wissig et al., 2013). (b) Adaptation and neuronal correlates

  12. Innovative techniques for the production of energetic radicals for lunar processing including cold plasma processing of local planetary ores

    NASA Technical Reports Server (NTRS)

    Bullard, D.; Lynch, D. C.

    1992-01-01

    Hydrogen reduction of ilmenite has been studied by a number of investigators as a potential means for recovery of oxygen from lunar soil. Interest in this process has always rested with the simplicity of the flow diagram and the utilization of established technology. Effective utilization of hydrogen in the reduction process at temperatures of 1200 C and below has always been disappointing and, as such, has led other investigators to focus attention on other systems. Effective utilization of hydrogen in the reduction of ilmenite can be significantly enhanced in the presence of a non-equilibrium hydrogen plasma. Ilmenite at solid specimen temperatures of 600 C to 970 C were reacted in a hydrogen plasma. Those experiments revealed that hydrogen utilization can be significantly enhanced. At a specimen temperature of 850 C the fraction of H2 reacted was 24 percent compared to the 7 percent theoretical limit calculated with thermodynamic theory for the same temperature. An added advantage for a hydrogen plasma involves further reduction of TiO2. Reduction of the iron oxide in ilmenite yields TiO2 and metallic iron as by products. Titanium forms a number of oxides including TiO, Ti2O3, Ti3O5 and the Magneli oxides (Ti4O7 to Ti50O99). In conventional processing of ilmenite with hydrogen it is possible to reduce TiO2 to Ti7O13 within approximately an hour, but with poor utilization of hydrogen on the order of one mole of H2 per thousand. In the cold or non-equilibrium plasma TiO2 can be rapidly reduced to Ti2O3 with hydrogen utilization exceeding 10 percent. Based on design considerations of the plasma reactor greater utilization of the hydrogen in the reduction of TiO2 is possible.

  13. Multi-modal adaptive optics system including fundus photography and optical coherence tomography for the clinical setting.

    PubMed

    Salas, Matthias; Drexler, Wolfgang; Levecq, Xavier; Lamory, Barbara; Ritter, Markus; Prager, Sonja; Hafner, Julia; Schmidt-Erfurth, Ursula; Pircher, Michael

    2016-05-01

    We present a new compact multi-modal imaging prototype that combines an adaptive optics (AO) fundus camera with AO-optical coherence tomography (OCT) in a single instrument. The prototype allows acquiring AO fundus images with a field of view of 4°x4° and with a frame rate of 10fps. The exposure time of a single image is 10 ms. The short exposure time results in nearly motion artifact-free high resolution images of the retina. The AO-OCT mode allows acquiring volumetric data of the retina at 200kHz A-scan rate with a transverse resolution of ~4 µm and an axial resolution of ~5 µm. OCT imaging is acquired within a field of view of 2°x2° located at the central part of the AO fundus image. Recording of OCT volume data takes 0.8 seconds. The performance of the new system is tested in healthy volunteers and patients with retinal diseases.

  14. Multi-modal adaptive optics system including fundus photography and optical coherence tomography for the clinical setting

    PubMed Central

    Salas, Matthias; Drexler, Wolfgang; Levecq, Xavier; Lamory, Barbara; Ritter, Markus; Prager, Sonja; Hafner, Julia; Schmidt-Erfurth, Ursula; Pircher, Michael

    2016-01-01

    We present a new compact multi-modal imaging prototype that combines an adaptive optics (AO) fundus camera with AO-optical coherence tomography (OCT) in a single instrument. The prototype allows acquiring AO fundus images with a field of view of 4°x4° and with a frame rate of 10fps. The exposure time of a single image is 10 ms. The short exposure time results in nearly motion artifact-free high resolution images of the retina. The AO-OCT mode allows acquiring volumetric data of the retina at 200kHz A-scan rate with a transverse resolution of ~4 µm and an axial resolution of ~5 µm. OCT imaging is acquired within a field of view of 2°x2° located at the central part of the AO fundus image. Recording of OCT volume data takes 0.8 seconds. The performance of the new system is tested in healthy volunteers and patients with retinal diseases. PMID:27231621

  15. Modelling of an activated primary settling tank including the fermentation process and VFA elutriation.

    PubMed

    Ribes, J; Ferrer, J; Bouzas, A; Seco, A

    2002-10-01

    A complete model of a primary settler including both sedimentation and biological processes is presented. It is a one-dimensional model based on the solids flux concept and the conservation of mass that uses the Takács model for the settling velocity, which is corrected by a compression function in the lower layers. The biological model is based on the ASM2 and enlarged with the fermentation model proposed by this research group. The settler was split in ten layers and the flux terms in the mass balance for each layer is obtained by means of the settling model. A pilot plant has been operated to study the primary sludge fermentation and volatile fatty acids (VFA) elutriation in a primary settler tank. The model has been tested with pilot plant experimental data with very good results. It has been able to simulate the VFA production in the settler and their elutriation with the influent wastewater for all the studied experiments. The developed model is easily applicable to secondary settlers and thickeners, also taking into account biological activity inside them.

  16. Adapting Semantic Natural Language Processing Technology to Address Information Overload in Influenza Epidemic Management.

    PubMed

    Keselman, Alla; Rosemblat, Graciela; Kilicoglu, Halil; Fiszman, Marcelo; Jin, Honglan; Shin, Dongwook; Rindflesch, Thomas C

    2010-12-01

    Explosion of disaster health information results in information overload among response professionals. The objective of this project was to determine the feasibility of applying semantic natural language processing (NLP) technology to addressing this overload. The project characterizes concepts and relationships commonly used in disaster health-related documents on influenza pandemics, as the basis for adapting an existing semantic summarizer to the domain. Methods include human review and semantic NLP analysis of a set of relevant documents. This is followed by a pilot-test in which two information specialists use the adapted application for a realistic information seeking task. According to the results, the ontology of influenza epidemics management can be described via a manageable number of semantic relationships that involve concepts from a limited number of semantic types. Test users demonstrate several ways to engage with the application to obtain useful information. This suggests that existing semantic NLP algorithms can be adapted to support information summarization and visualization in influenza epidemics and other disaster health areas. However, additional research is needed in the areas of terminology development (as many relevant relationships and terms are not part of existing standardized vocabularies), NLP, and user interface design.

  17. Multilevel processes and cultural adaptation: Examples from past and present small-scale societies

    PubMed Central

    Reyes-García, V.; Balbo, A. L.; Gomez-Baggethun, E.; Gueze, M.; Mesoudi, A.; Richerson, P.; Rubio-Campillo, X.; Ruiz-Mallén, I.; Shennan, S.

    2016-01-01

    Cultural adaptation has become central in the context of accelerated global change with authors increasingly acknowledging the importance of understanding multilevel processes that operate as adaptation takes place. We explore the importance of multilevel processes in explaining cultural adaptation by describing how processes leading to cultural (mis)adaptation are linked through a complex nested hierarchy, where the lower levels combine into new units with new organizations, functions, and emergent properties or collective behaviours. After a brief review of the concept of “cultural adaptation” from the perspective of cultural evolutionary theory and resilience theory, the core of the paper is constructed around the exploration of multilevel processes occurring at the temporal, spatial, social and political scales. We do so by examining small-scale societies’ case studies. In each section, we discuss the importance of the selected scale for understanding cultural adaptation and then present an example that illustrates how multilevel processes in the selected scale help explain observed patterns in the cultural adaptive process. We end the paper discussing the potential of modelling and computer simulation for studying multilevel processes in cultural adaptation. PMID:27774109

  18. Alternative Optical Architectures for Multichannel Adaptive Optical Processing

    DTIC Science & Technology

    1993-04-01

    performance of the system can also be improved if we note that the input of EdO ) need not be centered at 9a but could be cenitred at -AO+A4La so that...characterization of a multichannel adaptive system that can perform cancellation of multiple wideband (In r!ll) interference sources in the presence...development of a single-loop electronic canceller for improved phase stability after the AO tapped delay line system . 14. SUBJECT TERMS ,I PANUI OF PACES

  19. Adaptation as a political process: adjusting to drought and conflict in Kenya's drylands.

    PubMed

    Eriksen, Siri; Lind, Jeremy

    2009-05-01

    In this article, we argue that people's adjustments to multiple shocks and changes, such as conflict and drought, are intrinsically political processes that have uneven outcomes. Strengthening local adaptive capacity is a critical component of adapting to climate change. Based on fieldwork in two areas in Kenya, we investigate how people seek to access livelihood adjustment options and promote particular adaptation interests through forming social relations and political alliances to influence collective decision-making. First, we find that, in the face of drought and conflict, relations are formed among individuals, politicians, customary institutions, and government administration aimed at retaining or strengthening power bases in addition to securing material means of survival. Second, national economic and political structures and processes affect local adaptive capacity in fundamental ways, such as through the unequal allocation of resources across regions, development policy biased against pastoralism, and competition for elected political positions. Third, conflict is part and parcel of the adaptation process, not just an external factor inhibiting local adaptation strategies. Fourth, there are relative winners and losers of adaptation, but whether or not local adjustments to drought and conflict compound existing inequalities depends on power relations at multiple geographic scales that shape how conflicting interests are negotiated locally. Climate change adaptation policies are unlikely to be successful or minimize inequity unless the political dimensions of local adaptation are considered; however, existing power structures and conflicts of interests represent political obstacles to developing such policies.

  20. Context-Aware Design for Process Flexibility and Adaptation

    ERIC Educational Resources Information Center

    Yao, Wen

    2012-01-01

    Today's organizations face continuous and unprecedented changes in their business environment. Traditional process design tools tend to be inflexible and can only support rigidly defined processes (e.g., order processing in the supply chain). This considerably restricts their real-world applications value, especially in the dynamic and…

  1. Adaptation and habitat selection in the eco-evolutionary process.

    PubMed

    Morris, Douglas W

    2011-08-22

    The struggle for existence occurs through the vital rates of population growth. This basic fact demonstrates the tight connection between ecology and evolution that defines the emerging field of eco-evolutionary dynamics. An effective synthesis of the interdependencies between ecology and evolution is grounded in six principles. The mechanics of evolution specifies the origin and rules governing traits and evolutionary strategies. Traits and evolutionary strategies achieve their selective value through their functional relationships with fitness. Function depends on the underlying structure of variation and the temporal, spatial and organizational scales of evolution. An understanding of how changes in traits and strategies occur requires conjoining ecological and evolutionary dynamics. Adaptation merges these five pillars to achieve a comprehensive understanding of ecological and evolutionary change. I demonstrate the value of this world-view with reference to the theory and practice of habitat selection. The theory allows us to assess evolutionarily stable strategies and states of habitat selection, and to draw the adaptive landscapes for habitat-selecting species. The landscapes can then be used to forecast future evolution under a variety of climate change and other scenarios.

  2. Adaptive sparse signal processing for discrimination of satellite-based radiofrequency (RF) recordings of lightning events

    NASA Astrophysics Data System (ADS)

    Moody, Daniela I.; Smith, David A.

    2015-05-01

    For over two decades, Los Alamos National Laboratory programs have included an active research effort utilizing satellite observations of terrestrial lightning to learn more about the Earth's RF background. The FORTE satellite provided a rich satellite lightning database, which has been previously used for some event classification, and remains relevant for advancing lightning research. Lightning impulses are dispersed as they travel through the ionosphere, appearing as nonlinear chirps at the receiver on orbit. The data processing challenge arises from the combined complexity of the lightning source model, the propagation medium nonlinearities, and the sensor artifacts. We continue to develop modern event classification capability on the FORTE database using adaptive signal processing combined with compressive sensing techniques. The focus of our work is improved feature extraction using sparse representations in overcomplete analytical dictionaries. We explore two possible techniques for detecting lightning events, and showcase the algorithms on few representative data examples. We present preliminary results of our work and discuss future development.

  3. Preparedness Formation of the Future Vocational Education Teachers to Occupational Adaptation under Conditions of Globalization Processes

    ERIC Educational Resources Information Center

    Sushentseva, Liliya

    2014-01-01

    The problem of the preparedness formation of future teachers of vocational training to the professional adaptation under conditions of globalization processes in society is considered. The analysis of scientific and educational literature devoted to the study of occupational adaptation and preparedness formation of specialists to it is carried…

  4. Recasting Transfer as a Socio-Personal Process of Adaptable Learning

    ERIC Educational Resources Information Center

    Billett, Stephen

    2013-01-01

    Transfer is usually cast as an educational, rather than learning, problem. Yet, seeking to adapt what individuals know from one circumstance to another is a process more helpfully associated with learning, than a hybrid one called transfer. Adaptability comprises individuals construing what they experience, then aligning and reconciling with what…

  5. Adaptive information processing in auditory cortex. Annual report, 1 June 1987-31 May 1988

    SciTech Connect

    Weinberger, N.M.

    1988-05-31

    The fact that learning induces frequency-specific modification of receptive fields in auditory cortex implies that the functional organization of auditory (and perhaps other sensory) cortex comprises an adaptively-constituted information base. This project initiates the first systematic investigation of adaptive information processing in cerebral cortex. A major goal is to determine the circumstances under which adaptive information processing is induced by experience. This project also addresses central hypotheses about rules that govern adaptive information processing, at three levels of spatial scale: (a) parallel processing in different auditory fields: (b) modular processing in different cortical lamina within fields; (c) local processing in different neurons within the same locus within lamina. The author emphasized determining the learning circumstances under which adaptive information processing is invoked by the brain. Current studies reveal that the frequency receptive fields of neurons in the auditory cortex, and the physiologically plastic magnocellular medial geniculate nucleus, develop frequency-specific modification such that maximal shifts in tuning are at or adjacent to the signal frequency. Further, this adaptive re-tuning of neurons develops rapidly during habituation, classical conditioning, and instrumental avoidance conditioning. The generality of re-tuning has established that AIP during learning represents a general brain strategy for the acquisition and subsequent processing of information.

  6. Adaptive fuzzy modeling of the hypnotic process in anesthesia.

    PubMed

    Marrero, A; Méndez, J A; Reboso, J A; Martín, I; Calvo, J L

    2017-04-01

    This paper addresses the problem of patient model synthesis in anesthesia. Recent advanced drug infusion mechanisms use a patient model to establish the proper drug dose. However, due to the inherent complexity and variability of the patient dynamics, difficulty obtaining a good model is high. In this paper, a method based on fuzzy logic and genetic algorithms is proposed as an alternative to standard compartmental models. The model uses a Mamdani type fuzzy inference system developed in a two-step procedure. First, an offline model is obtained using information from real patients. Then, an adaptive strategy that uses genetic algorithms is implemented. The validation of the modeling technique was done using real data obtained from real patients in the operating room. Results show that the proposed method based on artificial intelligence appears to be an improved alternative to existing compartmental methodologies.

  7. Determination of processed animal proteins, including meat and bone meal, in animal feed.

    PubMed

    Gizzi, Giséile; von Holst, Christoph; Baeten, Vincent; Berben, Gilbert; van Raamsdonk, Leo

    2004-01-01

    An intercomparison study was conducted to determine the presence of processed animal proteins (PAPs), including meat and bone meal (MBM) from various species, in animal feed. The performances of different methods, such as microscopy, polymerase chain reaction (PCR), immunoassays, and a protocol based on iquid chromatography (LC), were compared. Laboratories were asked to analyze for PAPs from all terrestrial animals and fish (total PAPs); mammalian PAPs; ruminant PAPs; and porcine PAPs. They were free to use their method of choice. In addition, laboratories using microscopy were asked to determine the presence of PAPs from terrestrial animals, which is applicable only to microscopy. For total PAPs microscopy, LC and some immunoassays showed sufficient results at a concentration as low as 0.1% MBM in the feed. In contrast, PCR was not fit for purpose. In differentiating between MBM from terrestrial animals and fishmeal, microscopy detected 0.5% of terrestrial MBM in feed in the presence of 5% fishmeal, but was less successful when the concentration of MBM from terrestrial animals was 0.1%. The animal-specific determination of MBM from mammals or, more specifically from either ruminants or pigs, by PCR showed poor results, as indicated by a high number of false-positive and false-negative results. The only PCR method that scored quite well was applied by a member of the organizer team of the study. Immunoassays scored much better than PCR, showing sufficient sensitivity but some deficiency in terms of specificity. The results also demonstrated that the reliable determination of MBM from ruminants has not been resolved, especially for low concentrations of MBM (0.1%) in feed. Comparison of the results for mammalian MBM from all methods indicated that, for control purposes, the immunoassay method, especially when applied as dipsticks, could be used as a rapid screening method combined with microscopy to confirm the positive samples. However, implementation of such a

  8. It's Time to Revamp the Parent-Teacher Conference Process: Let's Include the Child!

    ERIC Educational Resources Information Center

    Boazman, Janette

    2014-01-01

    This article focuses on the fact that very often the traditional parent-teacher conference process is missing the most important stake holder, the child. The author asks the reader to clear the traditional image of parent-teacher conferences from their mind and imagine a conference process and setting that has the potential to bring together…

  9. Speech-Language Therapists' Process of Including Significant Others in Aphasia Rehabilitation

    ERIC Educational Resources Information Center

    Hallé, Marie-Christine; Le Dorze, Guylaine; Mingant, Anne

    2014-01-01

    Background: Although aphasia rehabilitation should include significant others, it is currently unknown how this recommendation is adopted in speech-language therapy practice. Speech-language therapists' (SLTs) experience of including significant others in aphasia rehabilitation is also understudied, yet a better understanding of clinical…

  10. Application of Non-Kolmogorovian Probability and Quantum Adaptive Dynamics to Unconscious Inference in Visual Perception Process

    NASA Astrophysics Data System (ADS)

    Accardi, Luigi; Khrennikov, Andrei; Ohya, Masanori; Tanaka, Yoshiharu; Yamato, Ichiro

    2016-07-01

    Recently a novel quantum information formalism — quantum adaptive dynamics — was developed and applied to modelling of information processing by bio-systems including cognitive phenomena: from molecular biology (glucose-lactose metabolism for E.coli bacteria, epigenetic evolution) to cognition, psychology. From the foundational point of view quantum adaptive dynamics describes mutual adapting of the information states of two interacting systems (physical or biological) as well as adapting of co-observations performed by the systems. In this paper we apply this formalism to model unconscious inference: the process of transition from sensation to perception. The paper combines theory and experiment. Statistical data collected in an experimental study on recognition of a particular ambiguous figure, the Schröder stairs, support the viability of the quantum(-like) model of unconscious inference including modelling of biases generated by rotation-contexts. From the probabilistic point of view, we study (for concrete experimental data) the problem of contextuality of probability, its dependence on experimental contexts. Mathematically contextuality leads to non-Komogorovness: probability distributions generated by various rotation contexts cannot be treated in the Kolmogorovian framework. At the same time they can be embedded in a “big Kolmogorov space” as conditional probabilities. However, such a Kolmogorov space has too complex structure and the operational quantum formalism in the form of quantum adaptive dynamics simplifies the modelling essentially.

  11. Fast but fleeting: adaptive motor learning processes associated with aging and cognitive decline.

    PubMed

    Trewartha, Kevin M; Garcia, Angeles; Wolpert, Daniel M; Flanagan, J Randall

    2014-10-01

    Motor learning has been shown to depend on multiple interacting learning processes. For example, learning to adapt when moving grasped objects with novel dynamics involves a fast process that adapts and decays quickly-and that has been linked to explicit memory-and a slower process that adapts and decays more gradually. Each process is characterized by a learning rate that controls how strongly motor memory is updated based on experienced errors and a retention factor determining the movement-to-movement decay in motor memory. Here we examined whether fast and slow motor learning processes involved in learning novel dynamics differ between younger and older adults. In addition, we investigated how age-related decline in explicit memory performance influences learning and retention parameters. Although the groups adapted equally well, they did so with markedly different underlying processes. Whereas the groups had similar fast processes, they had different slow processes. Specifically, the older adults exhibited decreased retention in their slow process compared with younger adults. Within the older group, who exhibited considerable variation in explicit memory performance, we found that poor explicit memory was associated with reduced retention in the fast process, as well as the slow process. These findings suggest that explicit memory resources are a determining factor in impairments in the both the fast and slow processes for motor learning but that aging effects on the slow process are independent of explicit memory declines.

  12. Adaptation of in-situ microscopy for crystallization processes

    NASA Astrophysics Data System (ADS)

    Bluma, A.; Höpfner, T.; Rudolph, G.; Lindner, P.; Beutel, S.; Hitzmann, B.; Scheper, T.

    2009-08-01

    In biotechnological and pharmaceutical engineering, the study of crystallization processes gains importance. An efficient analytical inline sensor could help to improve the knowledge about these processes in order to increase efficiency and yields. The in-situ microscope (ISM) is an optical sensor developed for the monitoring of bioprocesses. A new application for this sensor is the monitoring in downstream processes, e.g. the crystallization of proteins and other organic compounds. This contribution shows new aspects of using in-situ microscopy to monitor crystallization processes. Crystals of different chemical compounds were precipitated from supersaturated solutions and the crystal growth was monitored. Exemplified morphological properties and different forms of crystals could be distinguished on the basis of offline experiments. For inline monitoring of crystallization processes, a special 0.5 L stirred tank reactor was developed and equipped with the in-situ microscope. This reactor was utilized to carry out batch experiments for crystallizations of O-acetylsalicyclic acid (ASS) and hen egg white lysozyme (HEWL). During the whole crystallization process, the in-situ microscope system acquired images directly from the crystallization broth. For the data evaluation, an image analysis algorithm was developed and implemented in the microscope analysis software.

  13. Vultures of the seas: hyperacidic stomachs in wandering albatrosses as an adaptation to dispersed food resources, including fishery wastes.

    PubMed

    Grémillet, David; Prudor, Aurélien; le Maho, Yvon; Weimerskirch, Henri

    2012-01-01

    Animals are primarily limited by their capacity to acquire food, yet digestive performance also conditions energy acquisition, and ultimately fitness. Optimal foraging theory predicts that organisms feeding on patchy resources should maximize their food loads within each patch, and should digest these loads quickly to minimize travelling costs between food patches. We tested the prediction of high digestive performance in wandering albatrosses, which can ingest prey of up to 3 kg, and feed on highly dispersed food resources across the southern ocean. GPS-tracking of 40 wandering albatrosses from the Crozet archipelago during the incubation phase confirmed foraging movements of between 475-4705 km, which give birds access to a variety of prey, including fishery wastes. Moreover, using miniaturized, autonomous data recorders placed in the stomach of three birds, we performed the first-ever measurements of gastric pH and temperature in procellariformes. These revealed surprisingly low pH levels (average 1.50±0.13), markedly lower than in other seabirds, and comparable to those of vultures feeding on carrion. Such low stomach pH gives wandering albatrosses a strategic advantage since it allows them a rapid chemical breakdown of ingested food and therefore a rapid digestion. This is useful for feeding on patchy, natural prey, but also on fishery wastes, which might be an important additional food resource for wandering albatrosses.

  14. Vultures of the Seas: Hyperacidic Stomachs in Wandering Albatrosses as an Adaptation to Dispersed Food Resources, including Fishery Wastes

    PubMed Central

    Grémillet, David; Prudor, Aurélien; le Maho, Yvon; Weimerskirch, Henri

    2012-01-01

    Animals are primarily limited by their capacity to acquire food, yet digestive performance also conditions energy acquisition, and ultimately fitness. Optimal foraging theory predicts that organisms feeding on patchy resources should maximize their food loads within each patch, and should digest these loads quickly to minimize travelling costs between food patches. We tested the prediction of high digestive performance in wandering albatrosses, which can ingest prey of up to 3 kg, and feed on highly dispersed food resources across the southern ocean. GPS-tracking of 40 wandering albatrosses from the Crozet archipelago during the incubation phase confirmed foraging movements of between 475–4705 km, which give birds access to a variety of prey, including fishery wastes. Moreover, using miniaturized, autonomous data recorders placed in the stomach of three birds, we performed the first-ever measurements of gastric pH and temperature in procellariformes. These revealed surprisingly low pH levels (average 1.50±0.13), markedly lower than in other seabirds, and comparable to those of vultures feeding on carrion. Such low stomach pH gives wandering albatrosses a strategic advantage since it allows them a rapid chemical breakdown of ingested food and therefore a rapid digestion. This is useful for feeding on patchy, natural prey, but also on fishery wastes, which might be an important additional food resource for wandering albatrosses. PMID:22701581

  15. "The Gaze Heuristic:" Biography of an Adaptively Rational Decision Process.

    PubMed

    Hamlin, Robert P

    2017-02-21

    This article is a case study that describes the natural and human history of the gaze heuristic. The gaze heuristic is an interception heuristic that utilizes a single input (deviation from a constant angle of approach) repeatedly as a task is performed. Its architecture, advantages, and limitations are described in detail. A history of the gaze heuristic is then presented. In natural history, the gaze heuristic is the only known technique used by predators to intercept prey. In human history the gaze heuristic was discovered accidentally by Royal Air Force (RAF) fighter command just prior to World War II. As it was never discovered by the Luftwaffe, the technique conferred a decisive advantage upon the RAF throughout the war. After the end of the war in America, German technology was combined with the British heuristic to create the Sidewinder AIM9 missile, the most successful autonomous weapon ever built. There are no plans to withdraw it or replace its guiding gaze heuristic. The case study demonstrates that the gaze heuristic is a specific heuristic type that takes a single best input at the best time (take the best(2) ). Its use is an adaptively rational response to specific, rapidly evolving decision environments that has allowed those animals/humans/machines who use it to survive, prosper, and multiply relative to those who do not.

  16. Process- and controller-adaptations determine the physiological effects of cold acclimation.

    PubMed

    Werner, Jürgen

    2008-09-01

    Experimental results on physiological effects of cold adaptation seem confusing and apparently incompatible with one another. This paper will explain that a substantial part of such a variety of results may be deduced from a common functional concept. A core/shell treatment ("model") of the thermoregulatory system is used with mean body temperature as the controlled variable. Adaptation, as a higher control level, is introduced into the system. Due to persistent stressors, either the (heat transfer) process or the controller properties (parameters) are adjusted (or both). It is convenient to call the one "process adaptation" and the other "controller adaptation". The most commonly demonstrated effect of autonomic cold acclimation is a change in the controller threshold. The analysis shows that this necessarily means a lowering of body temperature because of a lowered metabolic rate. This explains experimental results on both Europeans in the climatic chamber and Australian Aborigines in a natural environment. Exclusive autonomic process adaptation occurs in the form of a better insulation. The analysis explains why the post-adaptive steady-state can only be achieved, if the controller system reduces metabolism and why in spite of this the new state is inevitably characterized by a rise in body temperature. If both process and controller adaptations are simultaneously present, there may be not any change of body temperature at all, e.g., as demonstrated in animal experiments. Whether this kind of adaptation delivers a decrease, an increase or no change of mean body temperature, depends on the proportion of process and controller adaptation.

  17. Psychosocial intervention effects on adaptation, disease course and biobehavioral processes in cancer.

    PubMed

    Antoni, Michael H

    2013-03-01

    A diagnosis of cancer and subsequent treatments place demands on psychological adaptation. Behavioral research suggests the importance of cognitive, behavioral, and social factors in facilitating adaptation during active treatment and throughout cancer survivorship, which forms the rationale for the use of many psychosocial interventions in cancer patients. This cancer experience may also affect physiological adaptation systems (e.g., neuroendocrine) in parallel with psychological adaptation changes (negative affect). Changes in adaptation may alter tumor growth-promoting processes (increased angiogenesis, migration and invasion, and inflammation) and tumor defense processes (decreased cellular immunity) relevant for cancer progression and the quality of life of cancer patients. Some evidence suggests that psychosocial intervention can improve psychological and physiological adaptation indicators in cancer patients. However, less is known about whether these interventions can influence tumor activity and tumor growth-promoting processes and whether changes in these processes could explain the psychosocial intervention effects on recurrence and survival documented to date. Documenting that psychosocial interventions can modulate molecular activities (e.g., transcriptional indicators of cell signaling) that govern tumor promoting and tumor defense processes on the one hand, and clinical disease course on the other is a key challenge for biobehavioral oncology research. This mini-review will summarize current knowledge on psychological and physiological adaptation processes affected throughout the stress of the cancer experience, and the effects of psychosocial interventions on psychological adaptation, cancer disease progression, and changes in stress-related biobehavioral processes that may mediate intervention effects on clinical cancer outcomes. Very recent intervention work in breast cancer will be used to illuminate emerging trends in molecular probes of

  18. Parallel processing for nonlinear dynamics simulations of structures including rotating bladed-disk assemblies

    NASA Technical Reports Server (NTRS)

    Hsieh, Shang-Hsien

    1993-01-01

    The principal objective of this research is to develop, test, and implement coarse-grained, parallel-processing strategies for nonlinear dynamic simulations of practical structural problems. There are contributions to four main areas: finite element modeling and analysis of rotational dynamics, numerical algorithms for parallel nonlinear solutions, automatic partitioning techniques to effect load-balancing among processors, and an integrated parallel analysis system.

  19. Method of solution preparation of polyolefin class polymers for electrospinning processing included

    NASA Technical Reports Server (NTRS)

    Rabolt, John F. (Inventor); Lee, Keun-Hyung (Inventor); Givens, Steven R. (Inventor)

    2011-01-01

    A process to make a polyolefin fiber which has the following steps: mixing at least one polyolefin into a solution at room temperature or a slightly elevated temperature to form a polymer solution and electrospinning at room temperature said polymer solution to form a fiber.

  20. Effects of Crowding and Attention on High-Levels of Motion Processing and Motion Adaptation

    PubMed Central

    Pavan, Andrea; Greenlee, Mark W.

    2015-01-01

    The motion after-effect (MAE) persists in crowding conditions, i.e., when the adaptation direction cannot be reliably perceived. The MAE originating from complex moving patterns spreads into non-adapted sectors of a multi-sector adapting display (i.e., phantom MAE). In the present study we used global rotating patterns to measure the strength of the conventional and phantom MAEs in crowded and non-crowded conditions, and when attention was directed to the adapting stimulus and when it was diverted away from the adapting stimulus. The results show that: (i) the phantom MAE is weaker than the conventional MAE, for both non-crowded and crowded conditions, and when attention was focused on the adapting stimulus and when it was diverted from it, (ii) conventional and phantom MAEs in the crowded condition are weaker than in the non-crowded condition. Analysis conducted to assess the effect of crowding on high-level of motion adaptation suggests that crowding is likely to affect the awareness of the adapting stimulus rather than degrading its sensory representation, (iii) for high-level of motion processing the attentional manipulation does not affect the strength of either conventional or phantom MAEs, neither in the non-crowded nor in the crowded conditions. These results suggest that high-level MAEs do not depend on attention and that at high-level of motion adaptation the effects of crowding are not modulated by attention. PMID:25615577

  1. Distributed Sensing and Processing Adaptive Collaboration Environment (D-SPACE)

    DTIC Science & Technology

    2014-07-01

    MapReduce to scalably query datagraphs in the SHARD graph-store. In Proceedings of the fourth international workshop on Data - intensive distributed ...of distributed relational data across multiple autonomous heterogeneous computing resources in environments with limited control, resource failures...this one year effort, we developed a model for processing distributed data across multiple heterogeneous computing resources. Our model exploits the

  2. The Adapted Dance Process: Planning, Partnering, and Performing

    ERIC Educational Resources Information Center

    Block, Betty A.; Johnson, Peggy V.

    2011-01-01

    This article contains specific planning, partnering, and performing techniques for fully integrating dancers with special needs into a dance pedagogy program. Each aspect is discussed within the context of the domains of learning. Fundamental partnering strategies are related to each domain as part of the integration process. The authors recommend…

  3. A multilevel examination of the relationships among training outcomes, mediating regulatory processes, and adaptive performance.

    PubMed

    Chen, Gilad; Thomas, Brian; Wallace, J Craig

    2005-09-01

    This study examined whether cognitive, affective-motivational, and behavioral training outcomes relate to posttraining regulatory processes and adaptive performance similarly at the individual and team levels of analysis. Longitudinal data were collected from 156 individuals composing 78 teams who were trained on and then performed a simulated flight task. Results showed that posttraining regulation processes related similarly to adaptive performance across levels. Also, regulation processes fully mediated the influences of self- and collective efficacy beliefs on individual and team adaptive performance. Finally, knowledge and skill more strongly and directly related to adaptive performance at the individual than the team level of analysis. Implications to theory and practice, limitations, and future directions are discussed.

  4. Oxygen assisted laser cutting mechanism—a laminar boundary layer approach including the combustion process

    NASA Astrophysics Data System (ADS)

    Yilbaş, B. S.; Sahin, A. Z.

    1995-06-01

    The present study examines the combined effects of chemical reactions taking place between a gas jet and molten metal, the cooling effect of the jet and the evaporation of metal, during a CO 2 laser cutting process. A laminar boundary layer approach was used to develop a theoretical model for the oxygen gas jet laser cutting mechanism. An experiment was carried out to monitor the keyhole formation using a video recorder and detect the light emitted from the entrance and exist surfaces of the workpiece using a fibre-optic probe during the cutting process. The experimental study was extended to employ two different workpiece materials (stainless steel and mild steel) at two thicknesses, and varying oxygen assisting gas pressures. It is found that the theoretical model developed in the present study is valid for a cutting speed of about 30 mm s -1 and all jet velocities up to sonic, since the effect of shock is excluded in the model.

  5. The evolution of intelligence: adaptive specializations versus general process.

    PubMed

    Macphail, E M; Bolhuis, J J

    2001-08-01

    Darwin argued that between-species differences in intelligence were differences of degree, not of kind. The contemporary ecological approach to animal cognition argues that animals have evolved species-specific and problem-specific processes to solve problems associated with their particular ecological niches: thus different species use different processes, and within a species, different processes are used to tackle problems involving different inputs. This approach contrasts both with Darwin's view and with the general process view, according to which the same central processes of learning and memory are used across an extensive range of problems involving very different inputs. We review evidence relevant to the claim that the learning and memory performance of non-human animals varies according to the nature of the stimuli involved. We first discuss the resource distribution hypothesis, olfactory learning-set formation, and the 'biological constraints' literature, but find no convincing support from these topics for the ecological account of cognition. We then discuss the claim that the performance of birds in spatial tasks of learning and memory is superior in species that depend heavily upon stored food compared to species that either show less dependence upon stored food or do not store food. If it could be shown that storing species enjoy a superiority specifically in spatial (and not non-spatial) tasks, this would argue that spatial tasks are indeed solved using different processes from those used in non-spatial tasks. Our review of this literature does not find a consistent superiority of storing over non-storing birds in spatial tasks, and, in particular, no evidence of enhanced superiority of storing species when the task demands are increased, by, for example, increasing the number of items to be recalled or the duration of the retention period. We discuss also the observation that the hippocampus of storing birds is larger than that of non

  6. Users' manual for the Hydroecological Integrity Assessment Process software (including the New Jersey Assessment Tools)

    USGS Publications Warehouse

    Henriksen, James A.; Heasley, John; Kennen, Jonathan G.; Nieswand, Steven

    2006-01-01

    Applying the Hydroecological Integrity Assessment Process involves four steps: (1) a hydrologic classification of relatively unmodified streams in a geographic area using long-term gage records and 171 ecologically relevant indices; (2) the identification of statistically significant, nonredundant, hydroecologically relevant indices associated with the five major flow components for each stream class; and (3) the development of a stream-classification tool and a hydrologic assessment tool. Four computer software tools have been developed.

  7. Process for removing and detoxifying cadmium from scrap metal including mixed waste

    SciTech Connect

    Kronberg, J.W.

    1994-07-01

    Cadmium-bearing scrap from nuclear applications, such as neutron shielding and reactor control and safety rods, must usually be handled as mixed waste since it is radioactive and the cadmium in it is both leachable and highly toxic. Removing the cadmium from this scrap, and converting it to a nonleachable and minimally radioactive form, would greatly simplify disposal or recycling. A process now under development will do this by shredding the scrap; leaching it with reagents which selectively dissolve out the cadmium; reprecipitating the cadmium as its highly insoluble sulfide; then fusing the sulfide into a glassy matrix to bring its leachability below EPA limits before disposal. Alternatively, the cadmium may be recovered for reuse. A particular advantage of the process is that all reagents (except the glass frit) can easily be recovered and reused in a nearly closed cycle, minimizing the risk of radioactive release. The process does not harm common metals such as aluminum, iron and stainless steel, and is also applicable to non-nuclear cadmium-bearing scrap such as nickel-cadmium batteries.

  8. Fast phase processing in off-axis holography by CUDA including parallel phase unwrapping.

    PubMed

    Backoach, Ohad; Kariv, Saar; Girshovitz, Pinhas; Shaked, Natan T

    2016-02-22

    We present parallel processing implementation for rapid extraction of the quantitative phase maps from off-axis holograms on the Graphics Processing Unit (GPU) of the computer using computer unified device architecture (CUDA) programming. To obtain efficient implementation, we parallelized both the wrapped phase map extraction algorithm and the two-dimensional phase unwrapping algorithm. In contrast to previous implementations, we utilized unweighted least squares phase unwrapping algorithm that better suits parallelism. We compared the proposed algorithm run times on the CPU and the GPU of the computer for various sizes of off-axis holograms. Using the GPU implementation, we extracted the unwrapped phase maps from the recorded off-axis holograms at 35 frames per second (fps) for 4 mega pixel holograms, and at 129 fps for 1 mega pixel holograms, which presents the fastest processing framerates obtained so far, to the best of our knowledge. We then used common-path off-axis interferometric imaging to quantitatively capture the phase maps of a micro-organism with rapid flagellum movements.

  9. [Disorders of adaptive processes in conductors of passenger cars].

    PubMed

    Kopirovskiĭ, K M; Delektorskiĭ, N V; Kutovoĭ, V S

    1998-01-01

    Passenger carriage conductors work under difficult conditions, including night working hours, unfavorable working and rest conditions with sleep impairment, and other poor factors. This makes it necessary to assume that the conductors should be given some advantages: privilege pension provision, shorter working travelling hours, longer intertrip rest and annual vacation, special nutrition, etc.

  10. Adapting a large database of point of care summarized guidelines: a process description

    PubMed Central

    Van de Velde, Stijn; Aertgeerts, Bert; Goossens, Martine; Fauquert, Benjamin; Kunnamo, Ilka; Van Royen, Paul

    2015-01-01

    Abstract Rationale, aims and objectives Questions posed at the point of care (POC) can be answered using POC summarized guidelines. To implement a national POC information resource, we subscribed to a large database of POC summarized guidelines to complement locally available guidelines. Our challenge was in developing a sustainable strategy for adapting almost 1000 summarized guidelines. The aim of this paper was to describe our process for adapting a database of POC summarized guidelines. Methods An adaptation process based on the ADAPTE framework was tailored to be used by a heterogeneous group of participants. Guidelines were assessed on content and on applicability to the Belgian context. To improve efficiency, we chose to first aim our efforts towards those guidelines most important to primary care doctors. Results Over a period of 3 years, we screened about 80% of 1000 international summarized guidelines. For those guidelines identified as most important for primary care doctors, we noted that in about half of the cases, remarks were made concerning content. On the other hand, at least two‐thirds of all screened guidelines required no changes when evaluating their local usability. Conclusions Adapting a large body of POC summarized guidelines using a formal adaptation process is possible, even when faced with limited resources. This can be done by creating an efficient and collaborative effort and ensuring user‐friendly procedures. Our experiences show that even though in most cases guidelines can be adopted without adaptations, careful review of guidelines developed in a different context remains necessary. Streamlining international efforts in adapting international POC information resources and adopting similar adaptation processes may lessen duplication efforts and prove more cost‐effective.

  11. The MSFC complementary metal oxide semiconductor (including multilevel interconnect metallization) process handbook

    NASA Technical Reports Server (NTRS)

    Bouldin, D. L.; Eastes, R. W.; Feltner, W. R.; Hollis, B. R.; Routh, D. E.

    1979-01-01

    The fabrication techniques for creation of complementary metal oxide semiconductor integrated circuits at George C. Marshall Space Flight Center are described. Examples of C-MOS integrated circuits manufactured at MSFC are presented with functional descriptions of each. Typical electrical characteristics of both p-channel metal oxide semiconductor and n-channel metal oxide semiconductor discrete devices under given conditions are provided. Procedures design, mask making, packaging, and testing are included.

  12. Process For Controlling Flow Rate Of Viscous Materials Including Use Of Nozzle With Changeable Openings

    DOEpatents

    Ellingson, William A.; Forster, George A.

    1999-11-02

    Apparatus and a method for controlling the flow rate of viscous materials through a nozzle includes an apertured main body and an apertured end cap coupled together and having an elongated, linear flow channel extending the length thereof. An end of the main body is disposed within the end cap and includes a plurality of elongated slots concentrically disposed about and aligned with the flow channel. A generally flat cam plate having a center aperture is disposed between the main body and end cap and is rotatable about the flow channel. A plurality of flow control vane assemblies are concentrically disposed about the flow channel and are coupled to the cam plate. Each vane assembly includes a vane element disposed adjacent the end of the flow channel. Rotation of the cam plate in a first direction causes a corresponding rotation of each of the vane elements for positioning the individual vane elements over the aperture in the end cap blocking flow through the flow channel, while rotation in an opposite direction removes the vane elements from the aperture and positions them about the flow channel in a nested configuration in the full open position, with a continuous range of vane element positions available between the full open and closed positions.

  13. Double pendulum model for a tennis stroke including a collision process

    NASA Astrophysics Data System (ADS)

    Youn, Sun-Hyun

    2015-10-01

    By means of adding a collision process between the ball and racket in the double pendulum model, we analyzed the tennis stroke. The ball and the racket system may be accelerated during the collision time; thus, the speed of the rebound ball does not simply depend on the angular velocity of the racket. A higher angular velocity sometimes gives a lower rebound ball speed. We numerically showed that the proper time-lagged racket rotation increased the speed of the rebound ball by 20%. We also showed that the elbow should move in the proper direction in order to add the angular velocity of the racket.

  14. The exact solution of Stokes' second problem including start-up process with fractional element

    NASA Astrophysics Data System (ADS)

    Hu, Kaixin; Zhu, Keqin

    2009-10-01

    The start-up process of Stokes’ second problem of a viscoelastic material with fractional element is studied. The fluid above an infinite flat plane is set in motion by a sudden acceleration of the plate to steady oscillation. Exact solutions are obtained by using Laplace transform and Fourier transform. It is found that the relationship between the first peak value and the one of equal-amplitude oscillations depends on the distance from the plate. The amplitude decreases for increasing frequency and increasing distance.

  15. Numerical simulation of wheel forming process including damage and thermal effects

    NASA Astrophysics Data System (ADS)

    Lestriez, P.; Mariage, J. F.; Saanouni, K.; Cherouat, A.

    2004-06-01

    Ductile (or plastic) damage often occurs during some metal forming processes caused by large plastic flow localisation. Accordingly, it is primordial for numerical tools used to simulate these processes to use fully coupled constitutive equations accounting for both isotropic and kinematics hardening and damage. In this work, fully coupled constitutive equations accounting for both combined isotropic and kinematic hardening with thermal effects as well as the ductile damage are used with the general purpose Finite Element code ABAQUS. First, the fully coupled constitutive equations in the framework of Continuum Damage Mechanics are presented. The associated numerical aspects are then presented using an implicit integration scheme for local time integration of the fully coupled constitutive equations and a dynamic explicit scheme to solve the associated initial and boundary value problem. This numerical approach is applied to the virtual forming of an axisymmetric wheel made in commercial steel. Starting from a cylindrical billet, the wheel is forged using rigid tools. The central hole of the billet is obtained with blanking operation. Finally the deburring operation is used to cut off the burr resulting from the forging operation. Both the temperature and the damage fields are carefully analysed for each forming stage.

  16. Thermal Capacitance (Slug) Calorimeter Theory Including Heat Losses and Other Decaying Processes

    NASA Technical Reports Server (NTRS)

    Hightower, T. Mark; Olivares, Ricardo A.; Philippidis, Daniel

    2008-01-01

    A mathematical model, termed the Slug Loss Model, has been developed for describing thermal capacitance (slug) calorimeter behavior when heat losses and other decaying processes are not negligible. This model results in the temperature time slope taking the mathematical form of exponential decay. When data is found to fit well to this model, it allows a heat flux value to be calculated that corrects for the losses and may be a better estimate of the cold wall fully catalytic heat flux, as is desired in arc jet testing. The model was applied to the data from a copper slug calorimeter inserted during a particularly severe high heating rate arc jet run to illustrate its use. The Slug Loss Model gave a cold wall heat flux 15% higher than the value of 2,250 W/sq cm obtained from the conventional approach to processing the data (where no correction is made for losses). For comparison, a Finite Element Analysis (FEA) model was created and applied to the same data, where conduction heat losses from the slug were simulated. The heat flux determined by the FEA model was found to be in close agreement with the heat flux determined by the Slug Loss Model.

  17. Neuroelectric adaptations to cognitive processing in virtual environments: an exercise-related approach.

    PubMed

    Vogt, Tobias; Herpers, Rainer; Scherfgen, David; Strüder, Heiko K; Schneider, Stefan

    2015-04-01

    Recently, virtual environments (VEs) are suggested to encourage users to exercise regularly. The benefits of chronic exercise on cognitive performance are well documented in non-VE neurophysiological and behavioural studies. Based on event-related potentials (ERP) such as the N200 and P300, cognitive processing may be interpreted on a neuronal level. However, exercise-related neuroelectric adaptation in VE remains widely unclear and thus characterizes the primary aim of the present study. Twenty-two healthy participants performed active (moderate cycling exercise) and passive (no exercise) sessions in three VEs (control, front, surround), each generating a different sense of presence. Within sessions, conditions were randomly assigned, each lasting 5 min and including a choice reaction-time task to assess cognitive performance. According to the international 10:20 system, EEG with real-time triggered stimulus onset was recorded, and peaks of N200 and P300 components (amplitude, latency) were exported for analysis. Heart rate was recorded, and sense of presence assessed prior to and following each session and condition. Results revealed an increase in ERP amplitudes (N200: p < 0.001; P300: p < 0.001) and latencies (N200: p < 0.001) that were most pronounced over fronto-central and occipital electrode sites relative to an increased sense of presence (p < 0.001); however, ERP were not modulated by exercise (each p > 0.05). Hypothesized to mirror cognitive processing, decreases of cognitive performance's accuracy and reaction time failed significance. With respect to previous research, the present neuroelectric adaptation gives reason to believe in compensative neuronal resources that balance demanding cognitive processing in VE to avoid behavioural inefficiency.

  18. Steady-state analysis of activated sludge processes with a settler model including sludge compression.

    PubMed

    Diehl, S; Zambrano, J; Carlsson, B

    2016-01-01

    A reduced model of a completely stirred-tank bioreactor coupled to a settling tank with recycle is analyzed in its steady states. In the reactor, the concentrations of one dominant particulate biomass and one soluble substrate component are modelled. While the biomass decay rate is assumed to be constant, growth kinetics can depend on both substrate and biomass concentrations, and optionally model substrate inhibition. Compressive and hindered settling phenomena are included using the Bürger-Diehl settler model, which consists of a partial differential equation. Steady-state solutions of this partial differential equation are obtained from an ordinary differential equation, making steady-state analysis of the entire plant difficult. A key result showing that the ordinary differential equation can be replaced with an approximate algebraic equation simplifies model analysis. This algebraic equation takes the location of the sludge-blanket during normal operation into account, allowing for the limiting flux capacity caused by compressive settling to easily be included in the steady-state mass balance equations for the entire plant system. This novel approach grants the possibility of more realistic solutions than other previously published reduced models, comprised of yet simpler settler assumptions. The steady-state concentrations, solids residence time, and the wastage flow ratio are functions of the recycle ratio. Solutions are shown for various growth kinetics; with different values of biomass decay rate, influent volumetric flow, and substrate concentration.

  19. Highlights from the Center for Adaptive Optics Treasury Survey of Distant Galaxies, Including H-band Photometry of a z=1.3 Supernova

    NASA Astrophysics Data System (ADS)

    Melbourne, J.; Barczys, M.; Wright, S. A.; Max, C. E.; Larkin, J.; Koo, D. C.; Perlmutter, S.; Steinbring, E.; Metevier, A.; Chun, M.

    2005-12-01

    The Center for Adaptive Optics Treasury Survey (CATS) is observing the deep HST galaxy fields (e.g., GOODS-N and S, COSMOS, GEMS, and EGS) with high-resolution near-infrared imaging from ground-based adaptive optics on large telescopes. Initial results from the first ten Keck laser guide star pointings are presented. Highlights include, 1) H-band (rest-frame R) photometry over maximum of a z=1.32 Type Ia supernova from the HST cluster supernova search of Perlmutter et al. (see poster of Dawson et al.); 2) a near-infrared study of small bulges of distant disk galaxies (z ˜0.6); 3) Stellar population synthesis models of AGN cores to z=1; and 4) Detection of lensed arcs around a z=0.20 cluster. CATS plans its first public data release in Fall 2006. This work is funded by the NSF Science and Technology Center for Adaptive Optics, managed by the University of California at Santa Cruz under the cooperative agreement No. AST-9876783.

  20. Modelling of adaptation processes of crops to water and nitrogen stress

    NASA Astrophysics Data System (ADS)

    Kovacs, G. J.

    2003-04-01

    In the early 1980-es the author published interpretations of his observations on special adaptation processes of crops. Those days it was not yet timely to include these details into a crop model. The knowledge has grown about the systems of crops and their environment, now it is appropriate to build these into systems models. From practical reasons 4M system model was chosen for this work. 4M has been developed at RISSAC, Budapest, Hungary based on CERES model and the advices of J.T. Ritchie. It includes the work of several Hungarian scientists. The newly modelled processes were as follows: (1) nitrate and ammonium concentration of soil solution in soil layers influenced by water transport processes and nitrogen transformation and transport processes, (2) root growth and distribution by the influence of available soil water and soil nitrogen, (3) changed transpiration rate influenced by radical change of availability of nitrogen. (4) changed distribution rate and redistribution of dry matter and nutrients in plants influenced by water and nitrogen stress. These processes have different consequences in the plant production depending on the phenological stage when the stress occurs. There are weather situations under the climate of the Carpathian base under which these the summer stress reactions can cause tons of losses in biomass and yield despite of abundant supply of fertilizers in spring. The phenomena can be characterised as spoiled maize stand interrupted by a heavy rainy period with strong nitrate leaching. In the dry period after the rainy period nitrogen shortage intensifies transpiration then the lack of water supply makes the plant to grow the roots fast in the deeper horizons. That leads to redistribution of biomass, loss of above ground DM, and deficiency of nutrients in the plant. In flowering stage it may lead to poor fertilization and smaller grain numbers consequently lower yield potential.

  1. Including natural systems into the system engineering process: benefits to spaceflight and beyond

    NASA Astrophysics Data System (ADS)

    Studor, George

    2014-03-01

    How did we get to the point where we don't have time to be inspired by the wonders of Nature? Our office walls, homes and city streets are so plain that even when we do escape to a retreat with nature all around us, we may be blind to its magnificence. Yet there are many who have applied what can be known of natural systems (NS) to create practical solutions, but often definite applications for them are lacking. Mimicry of natural systems is not only more possible than ever before, but the education and research programs in many major universities are churning out graduates with a real appreciation for Nature's complex integrated systems. What if these skills and perspectives were employed in the teams of systems engineers and the technology developers that support them to help the teams think "outside-the-box" of manmade inventions? If systems engineers (SE) and technology developers regularly asked the question, "what can we learn from Nature that will help us?" as a part of their processes, they would discover another set of potential solutions. Biomimicry and knowledge of natural systems is exploding. What does this mean for systems engineering and technology? Some disciplines such as robotics and medical devices must consider nature constantly. Perhaps it's time for all technology developers and systems engineers to perceive natural systems experts as potential providers of the technologies they need.

  2. Natural variation in stomatal abundance of Arabidopsis thaliana includes cryptic diversity for different developmental processes

    PubMed Central

    Delgado, Dolores; Alonso-Blanco, Carlos; Fenoll, Carmen; Mena, Montaña

    2011-01-01

    Background and Aims Current understanding of stomatal development in Arabidopsis thaliana is based on mutations producing aberrant, often lethal phenotypes. The aim was to discover if naturally occurring viable phenotypes would be useful for studying stomatal development in a species that enables further molecular analysis. Methods Natural variation in stomatal abundance of A. thaliana was explored in two collections comprising 62 wild accessions by surveying adaxial epidermal cell-type proportion (stomatal index) and density (stomatal and pavement cell density) traits in cotyledons and first leaves. Organ size variation was studied in a subset of accessions. For all traits, maternal effects derived from different laboratory environments were evaluated. In four selected accessions, distinct stomatal initiation processes were quantitatively analysed. Key Results and Conclusions Substantial genetic variation was found for all six stomatal abundance-related traits, which were weakly or not affected by laboratory maternal environments. Correlation analyses revealed overall relationships among all traits. Within each organ, stomatal density highly correlated with the other traits, suggesting common genetic bases. Each trait correlated between organs, supporting supra-organ control of stomatal abundance. Clustering analyses identified accessions with uncommon phenotypic patterns, suggesting differences among genetic programmes controlling the various traits. Variation was also found in organ size, which negatively correlated with cell densities in both organs and with stomatal index in the cotyledon. Relative proportions of primary and satellite lineages varied among the accessions analysed, indicating that distinct developmental components contribute to natural diversity in stomatal abundance. Accessions with similar stomatal indices showed different lineage class ratios, revealing hidden developmental phenotypes and showing that genetic determinants of primary and

  3. Multi-objective optimization of gear forging process based on adaptive surrogate meta-models

    NASA Astrophysics Data System (ADS)

    Meng, Fanjuan; Labergere, Carl; Lafon, Pascal; Daniel, Laurent

    2013-05-01

    In forging industry, net shape or near net shape forging of gears has been the subject of considerable research effort in the last few decades. So in this paper, a multi-objective optimization methodology of net shape gear forging process design has been discussed. The study is mainly done in four parts: building parametric CAD geometry model, simulating the forging process, fitting surrogate meta-models and optimizing the process by using an advanced algorithm. In order to maximally appropriate meta-models of the real response, an adaptive meta-model based design strategy has been applied. This is a continuous process: first, bui Id a preliminary version of the meta-models after the initial simulated calculations; second, improve the accuracy and update the meta-models by adding some new representative samplings. By using this iterative strategy, the number of the initial sample points for real numerical simulations is greatly decreased and the time for the forged gear design is significantly shortened. Finally, an optimal design for an industrial application of a 27-teeth gear forging process was introduced, which includes three optimization variables and two objective functions. A 3D FE nu merical simulation model is used to realize the process and an advanced thermo-elasto-visco-plastic constitutive equation is considered to represent the material behavior. The meta-model applied for this example is kriging and the optimization algorithm is NSGA-II. At last, a relatively better Pareto optimal front (POF) is gotten with gradually improving the obtained surrogate meta-models.

  4. Prism adaptation reverses the local processing bias in patients with right temporo-parietal junction lesions

    PubMed Central

    Rafal, Robert D.; List, Alexandra

    2009-01-01

    Lesions to the right temporo-parietal cortex commonly result in hemispatial neglect. Lesions to the same area are also associated with hyperattention to local details of a scene and difficulty perceiving the global structure. This local processing bias is an important factor contributing to neglect and may contribute to the higher prevalence of the disorder following right compared with left hemisphere strokes. In recent years, visuomotor adaptation to rightward-shifting prisms has been introduced as a promising treatment for hemispatial neglect. Explanations for these improvements have generally described a leftward realignment of attention, however, the present investigation provides evidence that prism adaptation reduces the local processing bias. Five patients with right temporal-parietal junction lesions were asked to identify the global or local levels of hierarchical figures before and after visuomotor adaptation to rightward-shifting prisms. Prior to prism adaptation the patients had difficulty ignoring the local elements when identifying the global component. Following prism adaptation, however, this pattern was reversed, with greater global interference during local level identification. The results suggest that prism adaptation may improve non-spatially lateralized deficits that contribute to the neglect syndrome. PMID:19416951

  5. Robust Brain-Machine Interface Design Using Optimal Feedback Control Modeling and Adaptive Point Process Filtering

    PubMed Central

    Carmena, Jose M.

    2016-01-01

    Much progress has been made in brain-machine interfaces (BMI) using decoders such as Kalman filters and finding their parameters with closed-loop decoder adaptation (CLDA). However, current decoders do not model the spikes directly, and hence may limit the processing time-scale of BMI control and adaptation. Moreover, while specialized CLDA techniques for intention estimation and assisted training exist, a unified and systematic CLDA framework that generalizes across different setups is lacking. Here we develop a novel closed-loop BMI training architecture that allows for processing, control, and adaptation using spike events, enables robust control and extends to various tasks. Moreover, we develop a unified control-theoretic CLDA framework within which intention estimation, assisted training, and adaptation are performed. The architecture incorporates an infinite-horizon optimal feedback-control (OFC) model of the brain’s behavior in closed-loop BMI control, and a point process model of spikes. The OFC model infers the user’s motor intention during CLDA—a process termed intention estimation. OFC is also used to design an autonomous and dynamic assisted training technique. The point process model allows for neural processing, control and decoder adaptation with every spike event and at a faster time-scale than current decoders; it also enables dynamic spike-event-based parameter adaptation unlike current CLDA methods that use batch-based adaptation on much slower adaptation time-scales. We conducted closed-loop experiments in a non-human primate over tens of days to dissociate the effects of these novel CLDA components. The OFC intention estimation improved BMI performance compared with current intention estimation techniques. OFC assisted training allowed the subject to consistently achieve proficient control. Spike-event-based adaptation resulted in faster and more consistent performance convergence compared with batch-based methods, and was robust to

  6. Robust Brain-Machine Interface Design Using Optimal Feedback Control Modeling and Adaptive Point Process Filtering.

    PubMed

    Shanechi, Maryam M; Orsborn, Amy L; Carmena, Jose M

    2016-04-01

    Much progress has been made in brain-machine interfaces (BMI) using decoders such as Kalman filters and finding their parameters with closed-loop decoder adaptation (CLDA). However, current decoders do not model the spikes directly, and hence may limit the processing time-scale of BMI control and adaptation. Moreover, while specialized CLDA techniques for intention estimation and assisted training exist, a unified and systematic CLDA framework that generalizes across different setups is lacking. Here we develop a novel closed-loop BMI training architecture that allows for processing, control, and adaptation using spike events, enables robust control and extends to various tasks. Moreover, we develop a unified control-theoretic CLDA framework within which intention estimation, assisted training, and adaptation are performed. The architecture incorporates an infinite-horizon optimal feedback-control (OFC) model of the brain's behavior in closed-loop BMI control, and a point process model of spikes. The OFC model infers the user's motor intention during CLDA-a process termed intention estimation. OFC is also used to design an autonomous and dynamic assisted training technique. The point process model allows for neural processing, control and decoder adaptation with every spike event and at a faster time-scale than current decoders; it also enables dynamic spike-event-based parameter adaptation unlike current CLDA methods that use batch-based adaptation on much slower adaptation time-scales. We conducted closed-loop experiments in a non-human primate over tens of days to dissociate the effects of these novel CLDA components. The OFC intention estimation improved BMI performance compared with current intention estimation techniques. OFC assisted training allowed the subject to consistently achieve proficient control. Spike-event-based adaptation resulted in faster and more consistent performance convergence compared with batch-based methods, and was robust to parameter

  7. Use of adapted Aspergillus niger in the bioleaching of spent refinery processing catalyst.

    PubMed

    Santhiya, Deenan; Ting, Yen-Peng

    2006-01-02

    Spent refinery processing catalyst is listed as a hazardous waste; the toxicity characteristic leaching procedure (TCLP) extracts of the catalyst are found to contain heavy metals at concentrations exceeding the regulated levels. In the present investigation, Aspergillus niger was adapted to single metal ions Ni, Mo or Al (at 100-2,000 mg/L in steps of 100mg/L) and then to a mixture of Ni, Mo and Al (at a mass ratio of 1:2:6, as approximately present in the spent catalyst). Adaptation experiments with single metals showed that the fungus could tolerate up to 1,000 mg/L Ni, 1,200 mg/L Mo and 2,000 mg/L Al. In the presence of a mixture of these metals, the fungus was able to tolerate up to 100mg/L Ni, 200mg/L Mo and 600 mg/L Al. One-step bioleaching experiments with 1 wt% spent catalyst (of particle size <37 microm) were carried out using un-adapted and various adapted fungal strains. In contrast to the adapted strains, the un-adapted strain showed no growth in the presence of the catalyst. Ni:Mo:Al-adapted strain was the most efficient in the leaching of metals from the catalyst (at 78.5% Ni, 82.3% Mo and 65.2% Al) over 30 days due to its tolerance to the toxic elements at 1 wt%. More importantly, the Ni:Mo:Al-adapted strain was capable of bioleaching up to 3 wt% spent catalyst. The TCLP extracts of the spent catalyst after bioleaching using the Ni:Mo:Al-adapted strain showed the concentrations of Ni and Mo were well within the regulated levels.

  8. Adaptation and validation of indicators concerning the sterilization process of supplies in Primary Health Care services1

    PubMed Central

    Passos, Isis Pienta Batista Dias; Padoveze, Maria Clara; Roseira, Camila Eugênia; de Figueiredo, Rosely Moralez

    2015-01-01

    OBJECTIVES: to adapt and validate, by expert consensus, a set of indicators used to assess the sterilization process of dental, medical and hospital supplies to be used in PHC services. METHOD: qualitative methodological study performed in two stages. The first stage included a focal group composed of experts to adapt the indicators to be used in PHC. In the second stage, the indicators were validated using a 4-point Likert scale, which was completed by judges. A Content Validity Index of ≥ 0.75 was considered to show approval of the indicators. RESULTS: the adaptations implemented by the focal group mainly referred to the physical structure, inclusion of dental care professionals, inclusion of chemical disinfection, and replacement of the hot air and moist heat sterilization methods. The validation stage resulted in an index of 0.96, which ranged from 0.90 to 1.00, for the components of the indicators. CONCLUSION: the judges considered the indicators after adaptation to be validated. Even though there may be differences among items processed around the world, there certainly are common characteristics, especially in countries with economic and cultural environments similar to Brazil. The inclusion of these indicators to assess the safety of healthcare supplies used in PHC services should be considered. PMID:25806643

  9. FLEXBAR—Flexible Barcode and Adapter Processing for Next-Generation Sequencing Platforms

    PubMed Central

    Dodt, Matthias; Roehr, Johannes T.; Ahmed, Rina; Dieterich, Christoph

    2012-01-01

    Quantitative and systems biology approaches benefit from the unprecedented depth of next-generation sequencing. A typical experiment yields millions of short reads, which oftentimes carry particular sequence tags. These tags may be: (a) specific to the sequencing platform and library construction method (e.g., adapter sequences); (b) have been introduced by experimental design (e.g., sample barcodes); or (c) constitute some biological signal (e.g., splice leader sequences in nematodes). Our software FLEXBAR enables accurate recognition, sorting and trimming of sequence tags with maximal flexibility, based on exact overlap sequence alignment. The software supports data formats from all current sequencing platforms, including color-space reads. FLEXBAR maintains read pairings and processes separate barcode reads on demand. Our software facilitates the fine-grained adjustment of sequence tag detection parameters and search regions. FLEXBAR is a multi-threaded software and combines speed with precision. Even complex read processing scenarios might be executed with a single command line call. We demonstrate the utility of the software in terms of read mapping applications, library demultiplexing and splice leader detection. FLEXBAR and additional information is available for academic use from the website: http://sourceforge.net/projects/flexbar/. PMID:24832523

  10. A cost-effective line-based light-balancing technique using adaptive processing.

    PubMed

    Hsia, Shih-Chang; Chen, Ming-Huei; Chen, Yu-Min

    2006-09-01

    The camera imaging system has been widely used; however, the displaying image appears to have an unequal light distribution. This paper presents novel light-balancing techniques to compensate uneven illumination based on adaptive signal processing. For text image processing, first, we estimate the background level and then process each pixel with nonuniform gain. This algorithm can balance the light distribution while keeping a high contrast in the image. For graph image processing, the adaptive section control using piecewise nonlinear gain is proposed to equalize the histogram. Simulations show that the performance of light balance is better than the other methods. Moreover, we employ line-based processing to efficiently reduce the memory requirement and the computational cost to make it applicable in real-time systems.

  11. Adaptation to leftward-shifting prisms reduces the global processing bias of healthy individuals.

    PubMed

    Bultitude, Janet H; Woods, Jill M

    2010-05-01

    When healthy individuals are presented with peripheral figures in which small letters are arranged to form a large letter, they are faster to identify the global- than the local-level information, and have difficulty ignoring global information when identifying the local level. The global reaction time (RT) advantage and global interference effect imply preferential processing of global-level information in the normal brain. This contrasts with the local processing bias demonstrated following lesions to the right temporo-parietal junction (TPJ), such as those that lead to hemispatial neglect (neglect). Recent research from our lab demonstrated that visuo-motor adaptation to rightward-shifting prisms, which ameliorates many leftward performance deficits of neglect patients, improved the local processing bias of patients with right TPJ lesions (Bultitude, Rafal, & List, 2009). Here we demonstrate that adaptation to leftward-shifting prisms, which can induce neglect-like performance in neurologically healthy individuals, also reduces the normal global processing bias. Forty-eight healthy participants were asked to identify the global or local forms of hierarchical figures before and after adaptation to leftward- or rightward-shifting prisms. Prior to prism adaptation, both groups had greater difficulty ignoring irrelevant global information when identifying the local level (global interference) compared to their ability to ignore irrelevant local-level information when identifying the global level (local interference). Participants who adapted to leftward-shifting prisms showed a significant reduction in global interference, but there was no change in the performance of the rightward-shifting Prism Group. These results show, for the first time, that in addition to previously demonstrated effects on lateralised attention, prism adaptation can influence non-lateralised spatial attention in healthy individuals.

  12. A fuzzy model based adaptive PID controller design for nonlinear and uncertain processes.

    PubMed

    Savran, Aydogan; Kahraman, Gokalp

    2014-03-01

    We develop a novel adaptive tuning method for classical proportional-integral-derivative (PID) controller to control nonlinear processes to adjust PID gains, a problem which is very difficult to overcome in the classical PID controllers. By incorporating classical PID control, which is well-known in industry, to the control of nonlinear processes, we introduce a method which can readily be used by the industry. In this method, controller design does not require a first principal model of the process which is usually very difficult to obtain. Instead, it depends on a fuzzy process model which is constructed from the measured input-output data of the process. A soft limiter is used to impose industrial limits on the control input. The performance of the system is successfully tested on the bioreactor, a highly nonlinear process involving instabilities. Several tests showed the method's success in tracking, robustness to noise, and adaptation properties. We as well compared our system's performance to those of a plant with altered parameters with measurement noise, and obtained less ringing and better tracking. To conclude, we present a novel adaptive control method that is built upon the well-known PID architecture that successfully controls highly nonlinear industrial processes, even under conditions such as strong parameter variations, noise, and instabilities.

  13. Access to Learning for Handicapped Children: A Handbook on the Instructional Adaptation Process. Field Test Version.

    ERIC Educational Resources Information Center

    Changar, Jerilynn; And Others

    The manual describes the results of a 36 month project to determine ways to modify existing curricula to meet the needs of special needs students in the mainstream. The handbook is designed in the main for administrators and facilitators as well as for teacher-adaptors. Each of eight steps in the adaptation process is broken down according to…

  14. Chinese Students and Scholars in the U.S.: An Intercultural Adaptation Process.

    ERIC Educational Resources Information Center

    Zhong, Mei

    An ethnographic study examined the culture of the Chinese students and scholars in America with a specific focus on their experiences in the cultural adaptation process. Subjects were three Chinese nationals (one female and two males) living in the area of a large midwestern university. Subjects were interviewed for about an hour each, with…

  15. Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli.

    PubMed

    Yosef, Ido; Goren, Moran G; Qimron, Udi

    2012-07-01

    The clustered regularly interspaced short palindromic repeats and their associated proteins (CRISPR/Cas) constitute a recently identified prokaryotic defense mechanism against invading nucleic acids. Activity of the CRISPR/Cas system comprises of three steps: (i) insertion of alien DNA sequences into the CRISPR array to prevent future attacks, in a process called 'adaptation', (ii) expression of the relevant proteins, as well as expression and processing of the array, followed by (iii) RNA-mediated interference with the alien nucleic acid. Here we describe a robust assay in Escherichia coli to explore the hitherto least-studied process, adaptation. We identify essential genes and DNA elements in the leader sequence and in the array which are essential for the adaptation step. We also provide mechanistic insights on the insertion of the repeat-spacer unit by showing that the first repeat serves as the template for the newly inserted repeat. Taken together, our results elucidate fundamental steps in the adaptation process of the CRISPR/Cas system.

  16. The Process of Adapting a German Pedagogy for Modern Mathematics Teaching in Japan

    ERIC Educational Resources Information Center

    Yamamoto, Shinya

    2006-01-01

    Modern geometry teaching in schools in Japan was modeled on the pedagogies of western countries. However, the core ideas of these pedagogies were often radically changed in the process of adaptation, resulting in teaching differing fundamentally from the original models. This paper discusses the radical changes the pedagogy of a German mathematics…

  17. Context-adaptive based CU processing for 3D-HEVC

    PubMed Central

    Shen, Liquan; An, Ping; Liu, Zhi

    2017-01-01

    The 3D High Efficiency Video Coding (3D-HEVC) standard aims to code 3D videos that usually contain multi-view texture videos and its corresponding depth information. It inherits the same quadtree prediction structure of HEVC to code both texture videos and depth maps. Each coding unit (CU) allows recursively splitting into four equal sub-CUs. At each CU depth level, it enables 10 types of inter modes and 35 types of intra modes in inter frames. Furthermore, the inter-view prediction tools are applied to each view in the test model of 3D-HEVC (HTM), which uses variable size disparity-compensated prediction to exploit inter-view correlation within neighbor views. It also exploits redundancies between a texture video and its associated depth using inter-component coding tools. These achieve the highest coding efficiency to code 3D videos but require a very high computational complexity. In this paper, we propose a context-adaptive based fast CU processing algorithm to jointly optimize the most complex components of HTM including CU depth level decision, mode decision, motion estimation (ME) and disparity estimation (DE) processes. It is based on the hypothesis that the optimal CU depth level, prediction mode and motion vector of a CU are correlated with those from spatiotemporal, inter-view and inter-component neighboring CUs. We analyze the video content based on coding information from neighboring CUs and early predict each CU into one of five categories i.e., DE-omitted CU, ME-DE-omitted CU, SPLIT CU, Non-SPLIT CU and normal CU, and then each type of CU adaptively adopts different processing strategies. Experimental results show that the proposed algorithm saves 70% encoder runtime on average with only a 0.1% BD-rate increase on coded views and 0.8% BD-rate increase on synthesized views. Our algorithm outperforms the state-of-the-art algorithms in terms of coding time saving or with better RD performance. PMID:28182719

  18. Construction of point process adaptive filter algorithms for neural systems using sequential Monte Carlo methods.

    PubMed

    Ergün, Ayla; Barbieri, Riccardo; Eden, Uri T; Wilson, Matthew A; Brown, Emery N

    2007-03-01

    The stochastic state point process filter (SSPPF) and steepest descent point process filter (SDPPF) are adaptive filter algorithms for state estimation from point process observations that have been used to track neural receptive field plasticity and to decode the representations of biological signals in ensemble neural spiking activity. The SSPPF and SDPPF are constructed using, respectively, Gaussian and steepest descent approximations to the standard Bayes and Chapman-Kolmogorov (BCK) system of filter equations. To extend these approaches for constructing point process adaptive filters, we develop sequential Monte Carlo (SMC) approximations to the BCK equations in which the SSPPF and SDPPF serve as the proposal densities. We term the two new SMC point process filters SMC-PPFs and SMC-PPFD, respectively. We illustrate the new filter algorithms by decoding the wind stimulus magnitude from simulated neural spiking activity in the cricket cercal system. The SMC-PPFs and SMC-PPFD provide more accurate state estimates at low number of particles than a conventional bootstrap SMC filter algorithm in which the state transition probability density is the proposal density. We also use the SMC-PPFs algorithm to track the temporal evolution of a spatial receptive field of a rat hippocampal neuron recorded while the animal foraged in an open environment. Our results suggest an approach for constructing point process adaptive filters using SMC methods.

  19. An Adaptive Altitude Information Fusion Method for Autonomous Landing Processes of Small Unmanned Aerial Rotorcraft

    PubMed Central

    Lei, Xusheng; Li, Jingjing

    2012-01-01

    This paper presents an adaptive information fusion method to improve the accuracy and reliability of the altitude measurement information for small unmanned aerial rotorcraft during the landing process. Focusing on the low measurement performance of sensors mounted on small unmanned aerial rotorcraft, a wavelet filter is applied as a pre-filter to attenuate the high frequency noises in the sensor output. Furthermore, to improve altitude information, an adaptive extended Kalman filter based on a maximum a posteriori criterion is proposed to estimate measurement noise covariance matrix in real time. Finally, the effectiveness of the proposed method is proved by static tests, hovering flight and autonomous landing flight tests. PMID:23201993

  20. Reaching Out: A Proactive Process to Include Young People with Learning Disabilities in Counselling in Secondary Schools in the UK

    ERIC Educational Resources Information Center

    Pattison, Sue

    2010-01-01

    This paper presents a proactive process to include young people with learning disabilities in mainstream counselling in secondary schools in the UK based on the findings of a consequential mixed methods research study. Data were collected from a quantitative and qualitative survey (n = 396) and qualitative semi-structured interviews (n = 15) with…

  1. 77 FR 56870 - New Process Gear, a Division of Magna Powertrain, Including On-Site Leased Workers From ABM...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... Leased Workers From ABM Janitorial Service Northeast, Inc., and IS One, Inc., East Syracuse, NY; Amended...). The notice was amended on June 21, 2012 to include on-site leased workers from ABM Janitorial Service... Syracuse, New York location of New Process Gear, a division of Magna Powertrain. The Department...

  2. Functional magnetic resonance imaging adaptation reveals the cortical networks for processing grasp-relevant object properties.

    PubMed

    Monaco, Simona; Chen, Ying; Medendorp, W P; Crawford, J D; Fiehler, Katja; Henriques, Denise Y P

    2014-06-01

    Grasping behaviors require the selection of grasp-relevant object dimensions, independent of overall object size. Previous neuroimaging studies found that the intraparietal cortex processes object size, but it is unknown whether the graspable dimension (i.e., grasp axis between selected points on the object) or the overall size of objects triggers activation in that region. We used functional magnetic resonance imaging adaptation to investigate human brain areas involved in processing the grasp-relevant dimension of real 3-dimensional objects in grasping and viewing tasks. Trials consisted of 2 sequential stimuli in which the object's grasp-relevant dimension, its global size, or both were novel or repeated. We found that calcarine and extrastriate visual areas adapted to object size regardless of the grasp-relevant dimension during viewing tasks. In contrast, the superior parietal occipital cortex (SPOC) and lateral occipital complex of the left hemisphere adapted to the grasp-relevant dimension regardless of object size and task. Finally, the dorsal premotor cortex adapted to the grasp-relevant dimension in grasping, but not in viewing, tasks, suggesting that motor processing was complete at this stage. Taken together, our results provide a complete cortical circuit for progressive transformation of general object properties into grasp-related responses.

  3. Multilevel regulation and signalling processes associated with adaptation to terminal drought in wild emmer wheat.

    PubMed

    Krugman, Tamar; Chagué, Véronique; Peleg, Zvi; Balzergue, Sandrine; Just, Jérémy; Korol, Abraham B; Nevo, Eviatar; Saranga, Yehoshua; Chalhoub, Boulos; Fahima, Tzion

    2010-05-01

    Low water availability is the major environmental factor limiting crop productivity. Transcriptome analysis was used to study terminal drought response in wild emmer wheat, Triticum dicoccoides, genotypes contrasting in their productivity and yield stability under drought stress. A total of 5,892 differentially regulated transcripts were identified between drought and well-watered control and/or between drought resistant (R) and drought susceptible (S) genotypes. Functional enrichment analyses revealed that multilevel regulatory and signalling processes were significantly enriched among the drought-induced transcripts, in particular in the R genotype. Therefore, further analyses were focused on selected 221 uniquely expressed or highly abundant transcripts in the R genotype, as potential candidates for drought resistance genes. Annotation of the 221 genes revealed that 26% of them are involved in multilevel regulation, including: transcriptional regulation, RNA binding, kinase activity and calcium and abscisic acid signalling implicated in stomatal closure. Differential expression patterns were also identified in genes known to be involved in drought adaptation pathways, such as: cell wall adjustment, cuticular wax deposition, lignification, osmoregulation, redox homeostasis, dehydration protection and drought-induced senescence. These results demonstrate the potential of wild emmer wheat as a source for candidate genes for improving drought resistance.

  4. NASA End-to-End Data System /NEEDS/ information adaptive system - Performing image processing onboard the spacecraft

    NASA Technical Reports Server (NTRS)

    Kelly, W. L.; Howle, W. M.; Meredith, B. D.

    1980-01-01

    The Information Adaptive System (IAS) is an element of the NASA End-to-End Data System (NEEDS) Phase II and is focused toward onbaord image processing. Since the IAS is a data preprocessing system which is closely coupled to the sensor system, it serves as a first step in providing a 'Smart' imaging sensor. Some of the functions planned for the IAS include sensor response nonuniformity correction, geometric correction, data set selection, data formatting, packetization, and adaptive system control. The inclusion of these sensor data preprocessing functions onboard the spacecraft will significantly improve the extraction of information from the sensor data in a timely and cost effective manner and provide the opportunity to design sensor systems which can be reconfigured in near real time for optimum performance. The purpose of this paper is to present the preliminary design of the IAS and the plans for its development.

  5. Adaptation to real motion reveals direction-selective interactions between real and implied motion processing.

    PubMed

    Lorteije, Jeannette A M; Kenemans, J Leon; Jellema, Tjeerd; van der Lubbe, Rob H J; Lommers, Marjolein W; van Wezel, Richard J A

    2007-08-01

    Viewing static pictures of running humans evokes neural activity in the dorsal motion-sensitive cortex. To establish whether this response arises from direction-selective neurons that are also involved in real motion processing, we measured the visually evoked potential to implied motion following adaptation to static or moving random dot patterns. The implied motion response was defined as the difference between evoked potentials to pictures with and without implied motion. Interaction between real and implied motion was found as a modulation of this difference response by the preceding motion adaptation. The amplitude of the implied motion response was significantly reduced after adaptation to motion in the same direction as the implied motion, compared to motion in the opposite direction. At 280 msec after stimulus onset, the average difference in amplitude reduction between opposite and same adapted direction was 0.5 muV on an average implied motion amplitude of 2.0 muV. These results indicate that the response to implied motion arises from direction-selective motion-sensitive neurons. This is consistent with interactions between real and implied motion processing at a neuronal level.

  6. Planar optical waveguide based sandwich assay sensors and processes for the detection of biological targets including protein markers, pathogens and cellular debris

    DOEpatents

    Martinez, Jennifer S.; Swanson, Basil I.; Grace, Karen M.; Grace, Wynne K.; Shreve, Andrew P.

    2009-06-02

    An assay element is described including recognition ligands bound to a film on a single mode planar optical waveguide, the film from the group of a membrane, a polymerized bilayer membrane, and a self-assembled monolayer containing polyethylene glycol or polypropylene glycol groups therein and an assay process for detecting the presence of a biological target is described including injecting a biological target-containing sample into a sensor cell including the assay element, with the recognition ligands adapted for binding to selected biological targets, maintaining the sample within the sensor cell for time sufficient for binding to occur between selected biological targets within the sample and the recognition ligands, injecting a solution including a reporter ligand into the sensor cell; and, interrogating the sample within the sensor cell with excitation light from the waveguide, the excitation light provided by an evanescent field of the single mode penetrating into the biological target-containing sample to a distance of less than about 200 nanometers from the waveguide thereby exciting the fluorescent-label in any bound reporter ligand within a distance of less than about 200 nanometers from the waveguide and resulting in a detectable signal.

  7. ADAPT: A knowledge-based synthesis tool for digital signal processing system design

    SciTech Connect

    Cooley, E.S.

    1988-01-01

    A computer aided synthesis tool for expansion, compression, and filtration of digital images is described. ADAPT, the Autonomous Digital Array Programming Tool, uses an extensive design knowledge base to synthesize a digital signal processing (DSP) system. Input to ADAPT can be either a behavioral description in English, or a block level specification via Petri Nets. The output from ADAPT comprises code to implement the DSP system on an array of processors. ADAPT is constructed using C, Prolog, and X Windows on a SUN 3/280 workstation. ADAPT knowledge encompasses DSP component information and the design algorithms and heuristics of a competent DSP designer. The knowledge is used to form queries for design capture, to generate design constraints from the user's responses, and to examine the design constraints. These constraints direct the search for possible DSP components and target architectures. Constraints are also used for partitioning the target systems into less complex subsystems. The subsystems correspond to architectural building blocks of the DSP design. These subsystems inherit design constraints and DSP characteristics from their parent blocks. Thus, a DSP subsystem or parent block, as designed by ADAPT, must meet the user's design constraints. Design solutions are sought by searching the Components section of the design knowledge base. Component behavior which matches or is similar to that required by the DSP subsystems is sought. Each match, which corresponds to a design alternative, is evaluated in terms of its behavior. When a design is sufficiently close to the behavior required by the user, detailed mathematical simulations may be performed to accurately determine exact behavior.

  8. Adapting existing natural language processing resources for cardiovascular risk factors identification in clinical notes.

    PubMed

    Khalifa, Abdulrahman; Meystre, Stéphane

    2015-12-01

    The 2014 i2b2 natural language processing shared task focused on identifying cardiovascular risk factors such as high blood pressure, high cholesterol levels, obesity and smoking status among other factors found in health records of diabetic patients. In addition, the task involved detecting medications, and time information associated with the extracted data. This paper presents the development and evaluation of a natural language processing (NLP) application conceived for this i2b2 shared task. For increased efficiency, the application main components were adapted from two existing NLP tools implemented in the Apache UIMA framework: Textractor (for dictionary-based lookup) and cTAKES (for preprocessing and smoking status detection). The application achieved a final (micro-averaged) F1-measure of 87.5% on the final evaluation test set. Our attempt was mostly based on existing tools adapted with minimal changes and allowed for satisfying performance with limited development efforts.

  9. Adapting School-Based Substance Use Prevention Curriculum Through Cultural Grounding: A Review and Exemplar of Adaptation Processes for Rural Schools

    PubMed Central

    Colby, Margaret; Hecht, Michael L.; Miller-Day, Michelle; Krieger, Janice L.; Syvertsen, Amy K.; Graham, John W.; Pettigrew, Jonathan

    2014-01-01

    A central challenge facing twenty-first century community-based researchers and prevention scientists is curriculum adaptation processes. While early prevention efforts sought to develop effective programs, taking programs to scale implies that they will be adapted, especially as programs are implemented with populations other than those with whom they were developed or tested. The principle of cultural grounding, which argues that health message adaptation should be informed by knowledge of the target population and by cultural insiders, provides a theoretical rational for cultural regrounding and presents an illustrative case of methods used to reground the keepin’ it REAL substance use prevention curriculum for a rural adolescent population. We argue that adaptation processes like those presented should be incorporated into the design and dissemination of prevention interventions. PMID:22961604

  10. Cameron - Optimized Compilation of Visual Programs for Image Processing on Adaptive Computing Systems (ACS)

    DTIC Science & Technology

    2002-01-01

    the Cameron project. The goal of the Cameron project is to make FPGAs and other adaptive computer systems available to more applications programmers...loops onto an FPGA , but this is invisible. SA-C therefore makes recon- gurable processors accessible to applications programmers with no hardware...happens that for SA-C programs, the host executable off-loads the processing of loops onto an FPGA , but this is invisible. SA-C therefore makes

  11. Short-term adaptation to a simple motor task: a physiological process preserved in multiple sclerosis.

    PubMed

    Mancini, L; Ciccarelli, O; Manfredonia, F; Thornton, J S; Agosta, F; Barkhof, F; Beckmann, C; De Stefano, N; Enzinger, C; Fazekas, F; Filippi, M; Gass, A; Hirsch, J G; Johansen-Berg, H; Kappos, L; Korteweg, T; Manson, S C; Marino, S; Matthews, P M; Montalban, X; Palace, J; Polman, C; Rocca, M; Ropele, S; Rovira, A; Wegner, C; Friston, K; Thompson, A; Yousry, T

    2009-04-01

    Short-term adaptation indicates the attenuation of the functional MRI (fMRI) response during repeated task execution. It is considered to be a physiological process, but it is unknown whether short-term adaptation changes significantly in patients with brain disorders, such as multiple sclerosis (MS). In order to investigate short-term adaptation during a repeated right-hand tapping task in both controls and in patients with MS, we analyzed the fMRI data collected in a large cohort of controls and MS patients who were recruited into a multi-centre European fMRI study. Four fMRI runs were acquired for each of the 55 controls and 56 MS patients at baseline and 33 controls and 26 MS patients at 1-year follow-up. The externally cued (1 Hz) right hand tapping movement was limited to 3 cm amplitude by using at all sites (7 at baseline and 6 at follow-up) identically manufactured wooden frames. No significant differences in cerebral activation were found between sites. Furthermore, our results showed linear response adaptation (i.e. reduced activation) from run 1 to run 4 (over a 25 minute period) in the primary motor area (contralateral more than ipsilateral), in the supplementary motor area and in the primary sensory cortex, sensory-motor cortex and cerebellum, bilaterally. This linear activation decay was the same in both control and patient groups, did not change between baseline and 1-year follow-up and was not influenced by the modest disease progression observed over 1 year. These findings confirm that the short-term adaptation to a simple motor task is a physiological process which is preserved in MS.

  12. Analytical and Experimental Performance Evaluation of BLE Neighbor Discovery Process Including Non-Idealities of Real Chipsets

    PubMed Central

    Perez-Diaz de Cerio, David; Hernández, Ángela; Valenzuela, Jose Luis; Valdovinos, Antonio

    2017-01-01

    The purpose of this paper is to evaluate from a real perspective the performance of Bluetooth Low Energy (BLE) as a technology that enables fast and reliable discovery of a large number of users/devices in a short period of time. The BLE standard specifies a wide range of configurable parameter values that determine the discovery process and need to be set according to the particular application requirements. Many previous works have been addressed to investigate the discovery process through analytical and simulation models, according to the ideal specification of the standard. However, measurements show that additional scanning gaps appear in the scanning process, which reduce the discovery capabilities. These gaps have been identified in all of the analyzed devices and respond to both regular patterns and variable events associated with the decoding process. We have demonstrated that these non-idealities, which are not taken into account in other studies, have a severe impact on the discovery process performance. Extensive performance evaluation for a varying number of devices and feasible parameter combinations has been done by comparing simulations and experimental measurements. This work also includes a simple mathematical model that closely matches both the standard implementation and the different chipset peculiarities for any possible parameter value specified in the standard and for any number of simultaneous advertising devices under scanner coverage. PMID:28273801

  13. Adaptive management

    USGS Publications Warehouse

    Allen, Craig R.; Garmestani, Ahjond S.

    2015-01-01

    Adaptive management is an approach to natural resource management that emphasizes learning through management where knowledge is incomplete, and when, despite inherent uncertainty, managers and policymakers must act. Unlike a traditional trial and error approach, adaptive management has explicit structure, including a careful elucidation of goals, identification of alternative management objectives and hypotheses of causation, and procedures for the collection of data followed by evaluation and reiteration. The process is iterative, and serves to reduce uncertainty, build knowledge and improve management over time in a goal-oriented and structured process.

  14. Ultrasound Nondestructive Evaluation (NDE) Imaging with Transducer Arrays and Adaptive Processing

    PubMed Central

    Li, Minghui; Hayward, Gordon

    2012-01-01

    This paper addresses the challenging problem of ultrasonic non-destructive evaluation (NDE) imaging with adaptive transducer arrays. In NDE applications, most materials like concrete, stainless steel and carbon-reinforced composites used extensively in industries and civil engineering exhibit heterogeneous internal structure. When inspected using ultrasound, the signals from defects are significantly corrupted by the echoes form randomly distributed scatterers, even defects that are much larger than these random reflectors are difficult to detect with the conventional delay-and-sum operation. We propose to apply adaptive beamforming to the received data samples to reduce the interference and clutter noise. Beamforming is to manipulate the array beam pattern by appropriately weighting the per-element delayed data samples prior to summing them. The adaptive weights are computed from the statistical analysis of the data samples. This delay-weight-and-sum process can be explained as applying a lateral spatial filter to the signals across the probe aperture. Simulations show that the clutter noise is reduced by more than 30 dB and the lateral resolution is enhanced simultaneously when adaptive beamforming is applied. In experiments inspecting a steel block with side-drilled holes, good quantitative agreement with simulation results is demonstrated. PMID:22368457

  15. Ultrasound nondestructive evaluation (NDE) imaging with transducer arrays and adaptive processing.

    PubMed

    Li, Minghui; Hayward, Gordon

    2012-01-01

    This paper addresses the challenging problem of ultrasonic non-destructive evaluation (NDE) imaging with adaptive transducer arrays. In NDE applications, most materials like concrete, stainless steel and carbon-reinforced composites used extensively in industries and civil engineering exhibit heterogeneous internal structure. When inspected using ultrasound, the signals from defects are significantly corrupted by the echoes form randomly distributed scatterers, even defects that are much larger than these random reflectors are difficult to detect with the conventional delay-and-sum operation. We propose to apply adaptive beamforming to the received data samples to reduce the interference and clutter noise. Beamforming is to manipulate the array beam pattern by appropriately weighting the per-element delayed data samples prior to summing them. The adaptive weights are computed from the statistical analysis of the data samples. This delay-weight-and-sum process can be explained as applying a lateral spatial filter to the signals across the probe aperture. Simulations show that the clutter noise is reduced by more than 30 dB and the lateral resolution is enhanced simultaneously when adaptive beamforming is applied. In experiments inspecting a steel block with side-drilled holes, good quantitative agreement with simulation results is demonstrated.

  16. Digital computer modeling of the process of reduction of redundancy in multichannel telemetry information by the method of adaptive discretization with associative sorting

    NASA Technical Reports Server (NTRS)

    Tolmadzheva, T. A.; Kantor, A. V.; Rozhkovskiy, L. V.

    1974-01-01

    Digital computer modeling of the process of adaptive discretization with associative sorting of actual multichannel telemetry information is discussed. The main task in modeling is production of initial data for determination of dependences describing the operation of the on-board information compression device. Conclusions are presented including the shortcomings of telemetric information used in modeling.

  17. Adaptive optics real time processing design for the advanced technology solar telescope

    NASA Astrophysics Data System (ADS)

    Richards, Kit

    2012-07-01

    The four meter Advanced Technology Solar Telescope (ATST) adaptive optics (AO) system will require at least twenty-four times the real time processing power as the Dunn Solar Telescope AO system. An FPGA solution for ATST AO real time processing is being pursued instead of the parallel DSP approach used for the Dunn AO76 system. An analysis shows FPGAs will have lower latency and lower hardware cost than an equivalent DSP solution. Interfacing to the proposed high speed camera and the deformable mirror will be simpler and have lower latency than with DSPs. This paper will discuss the current design and progress toward implementing the FPGA solution.

  18. Low Temperature Adaptation Is Not the Opposite Process of High Temperature Adaptation in Terms of Changes in Amino Acid Composition

    PubMed Central

    Yang, Ling-Ling; Tang, Shu-Kun; Huang, Ying; Zhi, Xiao-Yang

    2015-01-01

    Previous studies focused on psychrophilic adaptation generally have demonstrated that multiple mechanisms work together to increase protein flexibility and activity, as well as to decrease the thermostability of proteins. However, the relationship between high and low temperature adaptations remains unclear. To investigate this issue, we collected the available predicted whole proteome sequences of species with different optimal growth temperatures, and analyzed amino acid variations and substitutional asymmetry in pairs of homologous proteins from related species. We found that changes in amino acid composition associated with low temperature adaptation did not exhibit a coherent opposite trend when compared with changes in amino acid composition associated with high temperature adaptation. This result indicates that during their evolutionary histories the proteome-scale evolutionary patterns associated with prokaryotes exposed to low temperature environments were distinct from the proteome-scale evolutionary patterns associated with prokaryotes exposed to high temperature environments in terms of changes in amino acid composition of the proteins. PMID:26614525

  19. Adaptive signal processing of on-orbit radio frequency lightning recordings using overcomplete chirplet dictionaries

    NASA Astrophysics Data System (ADS)

    Moody, D. I.; Smith, D. A.; Light, T. E.; Suszcynsky, D. M.; Heavner, M.

    2013-12-01

    Ongoing research at Los Alamos National Laboratory studies the Earth's radio frequency (RF) transient background utilizing satellite-based RF observations of terrestrial lightning. Such impulsive signals are dispersed as they travel through the ionosphere and appear as nonlinear chirps at a receiver on-orbit. Signals of interest are typically observed in the presence of additive noise and structured clutter, including gated and continuous-wave (CW) sources. Detection and classification of such non-stationary signals against a complex, non-stationary background can present challenges for standard physics-based approaches. The FORTE satellite provided a rich satellite lightning database that has been previously used for some event classification. We now develop and implement new event classification capability on the FORTE database using state-of-the-art adaptive signal processing combined with compressive sensing and machine learning techniques. The focus of our work is improved feature extraction using representations in overcomplete analytical dictionaries. We choose a dictionary based on Gabor chirplets, which is designed to represent both pulses (chirping or non-chirping) and CW signals in very few representative elements from the dictionary. One feature extraction approach is based on obtaining sparse representations of our data using a matching pursuit search of the dictionary. A second approach is based on using a frame operator on the dictionary to obtain a dense representation of our data. We explore robustness of extracted features to changes in background clutter and noise levels. Both feature extraction algorithms will be used in conjunction with statistical classifiers to explore classification performance of major lightning types. Performance will be evaluated both qualitatively, as well as quantitatively using a small validated test set. We present preliminary results of our work and discuss future areas of development.

  20. Process-based quality management for clinical implementation of adaptive radiotherapy

    SciTech Connect

    Noel, Camille E.; Santanam, Lakshmi; Parikh, Parag J.; Mutic, Sasa

    2014-08-15

    Purpose: Intensity-modulated adaptive radiotherapy (ART) has been the focus of considerable research and developmental work due to its potential therapeutic benefits. However, in light of its unique quality assurance (QA) challenges, no one has described a robust framework for its clinical implementation. In fact, recent position papers by ASTRO and AAPM have firmly endorsed pretreatment patient-specific IMRT QA, which limits the feasibility of online ART. The authors aim to address these obstacles by applying failure mode and effects analysis (FMEA) to identify high-priority errors and appropriate risk-mitigation strategies for clinical implementation of intensity-modulated ART. Methods: An experienced team of two clinical medical physicists, one clinical engineer, and one radiation oncologist was assembled to perform a standard FMEA for intensity-modulated ART. A set of 216 potential radiotherapy failures composed by the forthcoming AAPM task group 100 (TG-100) was used as the basis. Of the 216 failures, 127 were identified as most relevant to an ART scheme. Using the associated TG-100 FMEA values as a baseline, the team considered how the likeliness of occurrence (O), outcome severity (S), and likeliness of failure being undetected (D) would change for ART. New risk priority numbers (RPN) were calculated. Failures characterized by RPN ≥ 200 were identified as potentially critical. Results: FMEA revealed that ART RPN increased for 38% (n = 48/127) of potential failures, with 75% (n = 36/48) attributed to failures in the segmentation and treatment planning processes. Forty-three of 127 failures were identified as potentially critical. Risk-mitigation strategies include implementing a suite of quality control and decision support software, specialty QA software/hardware tools, and an increase in specially trained personnel. Conclusions: Results of the FMEA-based risk assessment demonstrate that intensity-modulated ART introduces different (but not necessarily

  1. Process-based quality management for clinical implementation of adaptive radiotherapy

    PubMed Central

    Noel, Camille E.; Santanam, Lakshmi; Parikh, Parag J.; Mutic, Sasa

    2014-01-01

    Purpose: Intensity-modulated adaptive radiotherapy (ART) has been the focus of considerable research and developmental work due to its potential therapeutic benefits. However, in light of its unique quality assurance (QA) challenges, no one has described a robust framework for its clinical implementation. In fact, recent position papers by ASTRO and AAPM have firmly endorsed pretreatment patient-specific IMRT QA, which limits the feasibility of online ART. The authors aim to address these obstacles by applying failure mode and effects analysis (FMEA) to identify high-priority errors and appropriate risk-mitigation strategies for clinical implementation of intensity-modulated ART. Methods: An experienced team of two clinical medical physicists, one clinical engineer, and one radiation oncologist was assembled to perform a standard FMEA for intensity-modulated ART. A set of 216 potential radiotherapy failures composed by the forthcoming AAPM task group 100 (TG-100) was used as the basis. Of the 216 failures, 127 were identified as most relevant to an ART scheme. Using the associated TG-100 FMEA values as a baseline, the team considered how the likeliness of occurrence (O), outcome severity (S), and likeliness of failure being undetected (D) would change for ART. New risk priority numbers (RPN) were calculated. Failures characterized by RPN ≥ 200 were identified as potentially critical. Results: FMEA revealed that ART RPN increased for 38% (n = 48/127) of potential failures, with 75% (n = 36/48) attributed to failures in the segmentation and treatment planning processes. Forty-three of 127 failures were identified as potentially critical. Risk-mitigation strategies include implementing a suite of quality control and decision support software, specialty QA software/hardware tools, and an increase in specially trained personnel. Conclusions: Results of the FMEA-based risk assessment demonstrate that intensity-modulated ART introduces different (but not necessarily

  2. Initial results of a full kinetic simulation of RF H{sup −} source including Coulomb collision process

    SciTech Connect

    Mochizuki, S.; Shibata, T.; Nishida, K.; Hatayama, A.; Mattei, S.; Lettry, J.

    2015-04-08

    In order to evaluate Electron Energy Distribution Function (EEDF) more correctly for radio frequency inductively coupled plasma (RF-ICP) in hydrogen negative ion sources, the Electromagnetic Particle-In-Cell (EM-PIC) simulation code has been improved by taking into account electron-electron Coulomb collision. Binary collision model is employed to model Coulomb collision process and we have successfully modeled it. The preliminary calculation including Coulomb collision has been done and it is shown that Coulomb collision doesn’t have significant effects under the condition: electron density n{sub e} ∼ 10{sup 18} m{sup −3} and high gas pressure p{sub H{sub 2}} = 3 Pa, while it is necessary to include Coulomb collision under high electron density and low gas pressure conditions.

  3. Adaptive wave field synthesis for broadband active sound field reproduction: signal processing.

    PubMed

    Gauthier, Philippe-Aubert; Berry, Alain

    2008-04-01

    Sound field reproduction is a physical approach to the reproduction of the natural spatial character of hearing. It is also useful in experimental acoustics and psychoacoustics. Wave field synthesis (WFS) is a known open-loop technology which assumes that the reproduction environment is anechoic. A real reflective reproduction space thus reduces the objective accuracy of WFS. Recently, adaptive wave field synthesis (AWFS) was defined as a combination of WFS and active compensation. AWFS is based on the minimization of reproduction errors and on the penalization of departure from the WFS solution. This paper focuses on signal processing for AWFS. A classical adaptive algorithm is modified for AWFS: filtered-reference least-mean-square. This modified algorithm and the classical equivalent leaky algorithm have similar convergence properties except that the WFS solution influences the adaptation rule of the modified algorithm. The paper also introduces signal processing for independent radiation mode control of AWFS on the basis of plant decoupling. Simulation results for AWFS are introduced for free-field and reflective spaces. The two algorithms effectively reproduce the sound field and compensate for the reproduction errors at the error sensors. The independent radiation mode control allows a more flexible tuning of the algorithm.

  4. Coevolution of information processing and topology in hierarchical adaptive random Boolean networks

    NASA Astrophysics Data System (ADS)

    Górski, Piotr J.; Czaplicka, Agnieszka; Hołyst, Janusz A.

    2016-02-01

    Random Boolean Networks (RBNs) are frequently used for modeling complex systems driven by information processing, e.g. for gene regulatory networks (GRNs). Here we propose a hierarchical adaptive random Boolean Network (HARBN) as a system consisting of distinct adaptive RBNs (ARBNs) - subnetworks - connected by a set of permanent interlinks. We investigate mean node information, mean edge information as well as mean node degree. Information measures and internal subnetworks topology of HARBN coevolve and reach steady-states that are specific for a given network structure. The main natural feature of ARBNs, i.e. their adaptability, is preserved in HARBNs and they evolve towards critical configurations which is documented by power law distributions of network attractor lengths. The mean information processed by a single node or a single link increases with the number of interlinks added to the system. The mean length of network attractors and the mean steady-state connectivity possess minima for certain specific values of the quotient between the density of interlinks and the density of all links in networks. It means that the modular network displays extremal values of its observables when subnetworks are connected with a density a few times lower than a mean density of all links.

  5. Adaptive constructive processes and memory accuracy: Consequences of counterfactual simulations in young and older adults

    PubMed Central

    Gerlach, Kathy D.; Dornblaser, David W.; Schacter, Daniel L.

    2013-01-01

    People frequently engage in counterfactual thinking: mental simulations of alternative outcomes to past events. Like simulations of future events, counterfactual simulations serve adaptive functions. However, future simulation can also result in various kinds of distortions and has thus been characterized as an adaptive constructive process. Here we approach counterfactual thinking as such and examine whether it can distort memory for actual events. In Experiments 1a/b, young and older adults imagined themselves experiencing different scenarios. Participants then imagined the same scenario again, engaged in no further simulation of a scenario, or imagined a counterfactual outcome. On a subsequent recognition test, participants were more likely to make false alarms to counterfactual lures than novel scenarios. Older adults were more prone to these memory errors than younger adults. In Experiment 2, younger and older participants selected and performed different actions, then recalled performing some of those actions, imagined performing alternative actions to some of the selected actions, and did not imagine others. Participants, especially older adults, were more likely to falsely remember counterfactual actions than novel actions as previously performed. The findings suggest that counterfactual thinking can cause source confusion based on internally generated misinformation, consistent with its characterization as an adaptive constructive process. PMID:23560477

  6. Adaptive optimal control of highly dissipative nonlinear spatially distributed processes with neuro-dynamic programming.

    PubMed

    Luo, Biao; Wu, Huai-Ning; Li, Han-Xiong

    2015-04-01

    Highly dissipative nonlinear partial differential equations (PDEs) are widely employed to describe the system dynamics of industrial spatially distributed processes (SDPs). In this paper, we consider the optimal control problem of the general highly dissipative SDPs, and propose an adaptive optimal control approach based on neuro-dynamic programming (NDP). Initially, Karhunen-Loève decomposition is employed to compute empirical eigenfunctions (EEFs) of the SDP based on the method of snapshots. These EEFs together with singular perturbation technique are then used to obtain a finite-dimensional slow subsystem of ordinary differential equations that accurately describes the dominant dynamics of the PDE system. Subsequently, the optimal control problem is reformulated on the basis of the slow subsystem, which is further converted to solve a Hamilton-Jacobi-Bellman (HJB) equation. HJB equation is a nonlinear PDE that has proven to be impossible to solve analytically. Thus, an adaptive optimal control method is developed via NDP that solves the HJB equation online using neural network (NN) for approximating the value function; and an online NN weight tuning law is proposed without requiring an initial stabilizing control policy. Moreover, by involving the NN estimation error, we prove that the original closed-loop PDE system with the adaptive optimal control policy is semiglobally uniformly ultimately bounded. Finally, the developed method is tested on a nonlinear diffusion-convection-reaction process and applied to a temperature cooling fin of high-speed aerospace vehicle, and the achieved results show its effectiveness.

  7. Heparin promotes suspension adaptation process of CHO-TS28 cells by eliminating cell aggregation.

    PubMed

    Li, Ling; Qin, Jun; Feng, Qiang; Tang, Hao; Liu, Rong; Xu, Liqing; Chen, Zhinan

    2011-01-01

    While heparin has been shown to eliminate cell aggregation in suspension adaptations of insect and HEK293 cells for virus-based cell cultures, the role of heparin in long period serum-free suspension adaptation of the anchorage-dependent Chinese hamster ovary (CHO) cell lines remains inconclusive. In this paper, we explore the potential application of heparin in suspension adaptation of CHO cell line which produces an anti-human chimeric antibody cHAb18. Heparin showed a concentration-dependent inhibition of CHO-TS28 cell-to-cell adhesion, with a significant inhibitory effect occurring when the concentration exceeded 250 μg/ml (P < 0.001). Heparin also exhibited a cell aggregation elimination role at all concentrations (P < 0.001). Furthermore, heparin promoted cell growth and antibody secretion, with the highest cell density ((99.83 ± 12.21) × 10(4) cells/ml, P = 0.034) and maximum antibody yield ((9.46 ± 0.94) mg/l, P < 0.001) both occurring at 250 μg/ml heparin. When agitated, cell aggregates were effectively dispersed by 250 μg/ml heparin and a single-cell suspension culture process was promoted. In suspension adapted CHO-TS28 cells, cell growth rates and specific antibody productivity were maintained; while antigen-binding activity improved slightly. Together, our results show that heparin may promote suspension adaptation of anchorage-depended CHO cells by resisting cell aggregation without reducing cell growth, antibody secretion, and antigen-binding activity.

  8. Improved electromagnetic induction processing with novel adaptive matched filter and matched subspace detection

    NASA Astrophysics Data System (ADS)

    Hayes, Charles E.; McClellan, James H.; Scott, Waymond R.; Kerr, Andrew J.

    2016-05-01

    This work introduces two advances in wide-band electromagnetic induction (EMI) processing: a novel adaptive matched filter (AMF) and matched subspace detection methods. Both advances make use of recent work with a subspace SVD approach to separating the signal, soil, and noise subspaces of the frequency measurements The proposed AMF provides a direct approach to removing the EMI self-response while improving the signal to noise ratio of the data. Unlike previous EMI adaptive downtrack filters, this new filter will not erroneously optimize the EMI soil response instead of the EMI target response because these two responses are projected into separate frequency subspaces. The EMI detection methods in this work elaborate on how the signal and noise subspaces in the frequency measurements are ideal for creating the matched subspace detection (MSD) and constant false alarm rate matched subspace detection (CFAR) metrics developed by Scharf The CFAR detection metric has been shown to be the uniformly most powerful invariant detector.

  9. Maternal migration and child health: An analysis of disruption and adaptation processes in Benin

    PubMed Central

    Smith-Greenaway, Emily; Madhavan, Sangeetha

    2016-01-01

    Children of migrant mothers have lower vaccination rates compared to their peers with non-migrant mothers in low-income countries. Explanations for this finding are typically grounded in the disruption and adaptation perspectives of migration. Researchers argue that migration is a disruptive process that interferes with women’s economic well-being and social networks, and ultimately their health-seeking behaviors. With time, however, migrant women adapt to their new settings, and their health behaviors improve. Despite prominence in the literature, no research tests the salience of these perspectives to the relationship between maternal migration and child vaccination. We innovatively leverage Demographic and Health Survey data to test the extent to which disruption and adaptation processes underlie the relationship between maternal migration and child vaccination in the context of Benin—a West African country where migration is common and child vaccination rates have declined in recent years. By disaggregating children of migrants according to whether they were born before or after their mother’s migration, we confirm that migration does not lower children’s vaccination rates in Benin. In fact, children born after migration enjoy a higher likelihood of vaccination, whereas their peers born in the community from which their mother eventually migrates are less likely to be vaccinated. Although we find no support for the disruption perspective of migration, we do find evidence of adaptation: children born after migration have an increased likelihood of vaccination the longer their mother resides in the destination community prior to their birth. PMID:26463540

  10. General and craniofacial development are complex adaptive processes influenced by diversity.

    PubMed

    Brook, A H; O'Donnell, M Brook; Hone, A; Hart, E; Hughes, T E; Smith, R N; Townsend, G C

    2014-06-01

    Complex systems are present in such diverse areas as social systems, economies, ecosystems and biology and, therefore, are highly relevant to dental research, education and practice. A Complex Adaptive System in biological development is a dynamic process in which, from interacting components at a lower level, higher level phenomena and structures emerge. Diversity makes substantial contributions to the performance of complex adaptive systems. It enhances the robustness of the process, allowing multiple responses to external stimuli as well as internal changes. From diversity comes variation in outcome and the possibility of major change; outliers in the distribution enhance the tipping points. The development of the dentition is a valuable, accessible model with extensive and reliable databases for investigating the role of complex adaptive systems in craniofacial and general development. The general characteristics of such systems are seen during tooth development: self-organization; bottom-up emergence; multitasking; self-adaptation; variation; tipping points; critical phases; and robustness. Dental findings are compatible with the Random Network Model, the Threshold Model and also with the Scale Free Network Model which has a Power Law distribution. In addition, dental development shows the characteristics of Modularity and Clustering to form Hierarchical Networks. The interactions between the genes (nodes) demonstrate Small World phenomena, Subgraph Motifs and Gene Regulatory Networks. Genetic mechanisms are involved in the creation and evolution of variation during development. The genetic factors interact with epigenetic and environmental factors at the molecular level and form complex networks within the cells. From these interactions emerge the higher level tissues, tooth germs and mineralized teeth. Approaching development in this way allows investigation of why there can be variations in phenotypes from identical genotypes; the phenotype is the outcome

  11. Flexible Description and Adaptive Processing of Earth Observation Data through the BigEarth Platform

    NASA Astrophysics Data System (ADS)

    Gorgan, Dorian; Bacu, Victor; Stefanut, Teodor; Nandra, Cosmin; Mihon, Danut

    2016-04-01

    The Earth Observation data repositories extending periodically by several terabytes become a critical issue for organizations. The management of the storage capacity of such big datasets, accessing policy, data protection, searching, and complex processing require high costs that impose efficient solutions to balance the cost and value of data. Data can create value only when it is used, and the data protection has to be oriented toward allowing innovation that sometimes depends on creative people, which achieve unexpected valuable results through a flexible and adaptive manner. The users need to describe and experiment themselves different complex algorithms through analytics in order to valorize data. The analytics uses descriptive and predictive models to gain valuable knowledge and information from data analysis. Possible solutions for advanced processing of big Earth Observation data are given by the HPC platforms such as cloud. With platforms becoming more complex and heterogeneous, the developing of applications is even harder and the efficient mapping of these applications to a suitable and optimum platform, working on huge distributed data repositories, is challenging and complex as well, even by using specialized software services. From the user point of view, an optimum environment gives acceptable execution times, offers a high level of usability by hiding the complexity of computing infrastructure, and supports an open accessibility and control to application entities and functionality. The BigEarth platform [1] supports the entire flow of flexible description of processing by basic operators and adaptive execution over cloud infrastructure [2]. The basic modules of the pipeline such as the KEOPS [3] set of basic operators, the WorDeL language [4], the Planner for sequential and parallel processing, and the Executor through virtual machines, are detailed as the main components of the BigEarth platform [5]. The presentation exemplifies the development

  12. Synthetic Source Inversion Tests with the Full Complexity of Earthquake Source Processes, Including Both Supershear Rupture and Slip Reactivation

    NASA Astrophysics Data System (ADS)

    Song, Seok Goo; Dalguer, Luis A.

    2017-03-01

    Recent studies in dynamic source modeling and kinematic source inversion show that earthquake rupture may contain greater complexity than we previously anticipated, including multiple slipping at a given point on a fault. Finite source inversion methods suffer from the nonuniqueness of solutions, and it may become more serious if we aim to resolve more complex rupture models. In this study, we perform synthetic inversion tests with dynamically generated complex rupture models, including both supershear rupture and slip reactivation, to understand the possibility of resolving complex rupture processes by inverting seismic waveform data. We adopt a linear source inversion method with multiple windows, allowing for slipping from the nucleation of rupture to the termination at all locations along a fault. We regularize the model space effectively in the Bayesian framework and perform multiple inversion tests by considering the effect of inaccurate Green's functions and station distributions. We also perform a spectral stability analysis. Our results show that it may be possible to resolve both a supershear rupture front and reactivated secondary slipping using the linear inversion method if those complex features are well separated from the main rupture and produce a fair amount of seismic energy. It may be desirable to assume the full complexity of an earthquake rupture when we first develop finite source models after a major event occurs and then assume a simple rupture model for stability if the estimated models do not show a clear pattern of complex rupture processes.

  13. Efficient architecture for a multichannel array subbanding system with adaptive processing

    NASA Astrophysics Data System (ADS)

    Rabinkin, Daniel V.; Nguyen, Huy T.

    2000-11-01

    An architecture is presented for front-end processing in a wideband array system which samples real signals. Such a system may be encountered in cellular telephony, radar, or low SNR digital communications receivers. The subbanding of data enables system data rate reduction, and creates a narrowband condition for adaptive processing within the subbands. The front-end performs passband filtering, equalization, subband decomposition and adaptive beamforming. The subbanding operation is efficiently implemented using a prototype lowpass finite impulse response (FIR) filter, decomposed into polyphase form, combined with a Fast Fourier Transform (FFT) block and a bank of modulating postmultipliers. If the system acquires real inputs, a single FFT may be used to operate on two channels, but a channel separation network is then required for recovery of individual channel data. A sequence of steps is described based on data transformation techniques that enables a maximally efficient implementation of the processing stages and eliminates the need for channel separation. Operation count is reduced, and several layers of processing are eliminated.

  14. Enhanced peripheral visual processing in congenitally deaf humans is supported by multiple brain regions, including primary auditory cortex.

    PubMed

    Scott, Gregory D; Karns, Christina M; Dow, Mark W; Stevens, Courtney; Neville, Helen J

    2014-01-01

    Brain reorganization associated with altered sensory experience clarifies the critical role of neuroplasticity in development. An example is enhanced peripheral visual processing associated with congenital deafness, but the neural systems supporting this have not been fully characterized. A gap in our understanding of deafness-enhanced peripheral vision is the contribution of primary auditory cortex. Previous studies of auditory cortex that use anatomical normalization across participants were limited by inter-subject variability of Heschl's gyrus. In addition to reorganized auditory cortex (cross-modal plasticity), a second gap in our understanding is the contribution of altered modality-specific cortices (visual intramodal plasticity in this case), as well as supramodal and multisensory cortices, especially when target detection is required across contrasts. Here we address these gaps by comparing fMRI signal change for peripheral vs. perifoveal visual stimulation (11-15° vs. 2-7°) in congenitally deaf and hearing participants in a blocked experimental design with two analytical approaches: a Heschl's gyrus region of interest analysis and a whole brain analysis. Our results using individually-defined primary auditory cortex (Heschl's gyrus) indicate that fMRI signal change for more peripheral stimuli was greater than perifoveal in deaf but not in hearing participants. Whole-brain analyses revealed differences between deaf and hearing participants for peripheral vs. perifoveal visual processing in extrastriate visual cortex including primary auditory cortex, MT+/V5, superior-temporal auditory, and multisensory and/or supramodal regions, such as posterior parietal cortex (PPC), frontal eye fields, anterior cingulate, and supplementary eye fields. Overall, these data demonstrate the contribution of neuroplasticity in multiple systems including primary auditory cortex, supramodal, and multisensory regions, to altered visual processing in congenitally deaf adults.

  15. Sensory processing, school performance, and adaptive behavior of young school-age children with fetal alcohol spectrum disorders.

    PubMed

    Jirikowic, Tracy; Olson, Heather Carmichael; Kartin, Deborah

    2008-05-01

    This study described sensory processing behaviors and sensory-motor abilities in children with fetal alcohol spectrum disorders (FASD) and explored their relationship to home and school function. A clinic-referred sample of 25 children with FASD, ages 5 to 8 years, was compared with 26 children with typical development, balanced for age, gender, and race/ethnicity, on standardized tests examining sensory processing, sensory-motor performance, school performance, and adaptive behavior. Children with FASD scored significantly more poorly on sensory processing, sensory-motor, adaptive, and academic achievement measures, and demonstrated more problem behaviors at home and school. Correlations were significant between measures of sensory processing and sensory-motor performance, adaptive behavior, and some aspects of academic performance. Sensory processing and related foundational sensory-motor impairments should be considered when determining the developmental needs of children with FASD. These impairments may co-occur with and contribute, at least in part, to decreased adaptive and school function.

  16. Global References, Local Translation: Adaptation of the Bologna Process Degree Structure and Credit System at Universities in Cameroon

    ERIC Educational Resources Information Center

    Eta, Elizabeth Agbor; Vubo, Emmanuel Yenshu

    2016-01-01

    This article uses temporal comparison and thematic analytical approaches to analyse text documents and interviews, examining the adaptation of the Bologna Process degree structure and credit system in two sub-systems of education in Cameroon: the Anglo-Saxon and the French systems. The central aim is to verify whether such adaptation has replaced,…

  17. Adaptation of the IBM ECR (electric cantilever robot) robot to plutonium processing applications

    SciTech Connect

    Armantrout, G.A.; Pedrotti, L.R. ); Halter, E.A.; Crossfield, M. )

    1990-12-01

    The changing regulatory climate in the US is adding increasing incentive to reduce operator dose and TRU waste for DOE plutonium processing operations. To help achieve that goal the authors have begun adapting a small commercial overhead gantry robot, the IBM electric cantilever robot (ECR), to plutonium processing applications. Steps are being taken to harden this robot to withstand the dry, often abrasive, environment within a plutonium glove box and to protect the electronic components against alpha radiation. A mock-up processing system for the reduction of the oxide to a metal was prepared and successfully demonstrated. Design of a working prototype is now underway using the results of this mock-up study. 7 figs., 4 tabs.

  18. Adaptive Sparse Signal Processing for Discrimination of Satellite-based Radiofrequency (RF) Recordings of Lightning Events

    NASA Astrophysics Data System (ADS)

    Moody, D. I.; Smith, D. A.; Heavner, M.; Hamlin, T.

    2014-12-01

    Ongoing research at Los Alamos National Laboratory studies the Earth's radiofrequency (RF) background utilizing satellite-based RF observations of terrestrial lightning. The Fast On-orbit Recording of Transient Events (FORTE) satellite, launched in 1997, provided a rich RF lightning database. Application of modern pattern recognition techniques to this dataset may further lightning research in the scientific community, and potentially improve on-orbit processing and event discrimination capabilities for future satellite payloads. We extend sparse signal processing techniques to radiofrequency (RF) transient signals, and specifically focus on improved signature extraction using sparse representations in data-adaptive dictionaries. We present various processing options and classification results for on-board discharges, and discuss robustness and potential for capability development.

  19. OFDM Radar Space-Time Adaptive Processing by Exploiting Spatio-Temporal Sparsity

    SciTech Connect

    Sen, Satyabrata

    2013-01-01

    We propose a sparsity-based space-time adaptive processing (STAP) algorithm to detect a slowly-moving target using an orthogonal frequency division multiplexing (OFDM) radar. We observe that the target and interference spectra are inherently sparse in the spatio-temporal domain. Hence, we exploit that sparsity to develop an efficient STAP technique that utilizes considerably lesser number of secondary data and produces an equivalent performance as the other existing STAP techniques. In addition, the use of an OFDM signal increases the frequency diversity of our system, as different scattering centers of a target resonate at different frequencies, and thus improves the target detectability. First, we formulate a realistic sparse-measurement model for an OFDM radar considering both the clutter and jammer as the interfering sources. Then, we apply a residual sparse-recovery technique based on the LASSO estimator to estimate the target and interference covariance matrices, and subsequently compute the optimal STAP-filter weights. Our numerical results demonstrate a comparative performance analysis of the proposed sparse-STAP algorithm with four other existing STAP methods. Furthermore, we discover that the OFDM-STAP filter-weights are adaptable to the frequency-variabilities of the target and interference responses, in addition to the spatio-temporal variabilities. Hence, by better utilizing the frequency variabilities, we propose an adaptive OFDM-waveform design technique, and consequently gain a significant amount of STAP-performance improvement.

  20. Serum testosterone levels and excessive erythrocytosis during the process of adaptation to high altitudes

    PubMed Central

    Gonzales, Gustavo F

    2013-01-01

    Populations living at high altitudes (HAs), particularly in the Peruvian Andes, are characterized by a mixture of subjects with erythrocytosis (16 g dl−121 g dl−1). Elevated haemoglobin values (EE) are associated with chronic mountain sickness, a condition reflecting the lack of adaptation to HA. According to current data, native men from regions of HA are not adequately adapted to live at such altitudes if they have elevated serum testosterone levels. This seems to be due to an increased conversion of dehydroepiandrosterone sulphate (DHEAS) to testosterone. Men with erythrocytosis at HAs show higher serum androstenedione levels and a lower testosterone/androstenedione ratio than men with EE, suggesting reduced 17beta-hydroxysteroid dehydrogenase (17beta-HSD) activity. Lower 17beta-HSD activity via Δ4-steroid production in men with erythrocytosis at HA may protect against elevated serum testosterone levels, thus preventing EE. The higher conversion of DHEAS to testosterone in subjects with EE indicates increased 17beta-HSD activity via the Δ5-pathway. Currently, there are various situations in which people live (human biodiversity) with low or high haemoglobin levels at HA. Antiquity could be an important adaptation component for life at HA, and testosterone seems to participate in this process. PMID:23524530

  1. Adaptive behaviour and feedback processing integrate experience and instruction in reinforcement learning.

    PubMed

    Schiffer, Anne-Marike; Siletti, Kayla; Waszak, Florian; Yeung, Nick

    2017-02-01

    In any non-deterministic environment, unexpected events can indicate true changes in the world (and require behavioural adaptation) or reflect chance occurrence (and must be discounted). Adaptive behaviour requires distinguishing these possibilities. We investigated how humans achieve this by integrating high-level information from instruction and experience. In a series of EEG experiments, instructions modulated the perceived informativeness of feedback: Participants performed a novel probabilistic reinforcement learning task, receiving instructions about reliability of feedback or volatility of the environment. Importantly, our designs de-confound informativeness from surprise, which typically co-vary. Behavioural results indicate that participants used instructions to adapt their behaviour faster to changes in the environment when instructions indicated that negative feedback was more informative, even if it was simultaneously less surprising. This study is the first to show that neural markers of feedback anticipation (stimulus-preceding negativity) and of feedback processing (feedback-related negativity; FRN) reflect informativeness of unexpected feedback. Meanwhile, changes in P3 amplitude indicated imminent adjustments in behaviour. Collectively, our findings provide new evidence that high-level information interacts with experience-driven learning in a flexible manner, enabling human learners to make informed decisions about whether to persevere or explore new options, a pivotal ability in our complex environment.

  2. Multichannel adaptive signal detection in space-time colored compound-gaussian autoregressive processes

    NASA Astrophysics Data System (ADS)

    Xu, Qi; Ma, Xiaochuan; Yan, Shefeng; Hao, Chengpeng; Shi, Bo

    2012-12-01

    In this article, we consider the problem of adaptive detection for a multichannel signal in the presence of spatially and temporally colored compound-Gaussian disturbance. By modeling the disturbance as a multichannel autoregressive (AR) process, we first derive a parametric generalized likelihood ratio test against compound-Gaussian disturbance (CG-PGLRT) assuming that the true multichannel AR parameters are perfectly known. For the two-step GLRT design criterion, we combine the multichannel AR parameter estimation algorithm with three covariance matrix estimation strategies for compound-Gaussian environment, then obtain three adaptive CG-PGLRT detectors by replacing the ideal multichannel AR parameters with their estimates. Owing to treating the random texture components of disturbance as deterministic unknown parameters, all of the proposed detectors require no a priori knowledge about the disturbance statistics. The performance assessments are conducted by means of Monte Carlo trials. We focus on the issues of constant false alarm rate (CFAR) behavior, detection and false alarm probabilities. Numerical results show that the proposed adaptive CG-PGLRT detectors have dramatically ease the training and computational burden compared to the generalized likelihood ratio test-linear quadratic (GLRT-LQ) which is referred to as covariance matrix based detector and relies more heavily on training.

  3. Automatic target classification of slow moving ground targets using space-time adaptive processing

    NASA Astrophysics Data System (ADS)

    Malas, John Alexander

    2002-04-01

    Air-to-ground surveillance radar technologies are increasingly being used by theater commanders to detect, track, and identify ground moving targets. New radar automatic target recognition (ATR) technologies are being developed to aid the pilot in assessing the ground combat picture. Most air-to-ground surveillance radars use Doppler filtering techniques to separate target returns from ground clutter. Unfortunately, Doppler filter techniques fall short on performance when target geometry and ground vehicle speed result in low line of sight velocities. New clutter filter techniques compatible with emerging advancements in wideband radar operation are needed to support surveillance modes of radar operation when targets enter this low velocity regime. In this context, space-time adaptive processing (STAP) in conjunction with other algorithms offers a class of signal processing that provide improved target detection, tracking, and classification in the presence of interference through the adaptive nulling of both ground clutter and/or jamming. Of particular interest is the ability of the radar to filter and process the complex target signature data needed to generate high range resolution (HRR) signature profiles on ground targets. A new approach is proposed which will allow air-to-ground target classification of slow moving vehicles in clutter. A wideband STAP approach for clutter suppression is developed which preserves the amplitude integrity of returns from multiple range bins consistent with the HRR ATR approach. The wideband STAP processor utilizes narrowband STAP principles to generate a series of adaptive sub-band filters. Each sub-band filter output is used to construct the complete filtered response of the ground target. The performance of this new approach is demonstrated and quantified through the implementation of a one dimensional template-based minimum mean squared error classifier. Successful minimum velocity identification is defined in terms of

  4. An adaptive Gaussian process-based method for efficient Bayesian experimental design in groundwater contaminant source identification problems: ADAPTIVE GAUSSIAN PROCESS-BASED INVERSION

    SciTech Connect

    Zhang, Jiangjiang; Li, Weixuan; Zeng, Lingzao; Wu, Laosheng

    2016-08-01

    Surrogate models are commonly used in Bayesian approaches such as Markov Chain Monte Carlo (MCMC) to avoid repetitive CPU-demanding model evaluations. However, the approximation error of a surrogate may lead to biased estimations of the posterior distribution. This bias can be corrected by constructing a very accurate surrogate or implementing MCMC in a two-stage manner. Since the two-stage MCMC requires extra original model evaluations, the computational cost is still high. If the information of measurement is incorporated, a locally accurate approximation of the original model can be adaptively constructed with low computational cost. Based on this idea, we propose a Gaussian process (GP) surrogate-based Bayesian experimental design and parameter estimation approach for groundwater contaminant source identification problems. A major advantage of the GP surrogate is that it provides a convenient estimation of the approximation error, which can be incorporated in the Bayesian formula to avoid over-confident estimation of the posterior distribution. The proposed approach is tested with a numerical case study. Without sacrificing the estimation accuracy, the new approach achieves about 200 times of speed-up compared to our previous work using two-stage MCMC.

  5. A New Feedback-Based Method for Parameter Adaptation in Image Processing Routines

    PubMed Central

    Mikut, Ralf; Reischl, Markus

    2016-01-01

    The parametrization of automatic image processing routines is time-consuming if a lot of image processing parameters are involved. An expert can tune parameters sequentially to get desired results. This may not be productive for applications with difficult image analysis tasks, e.g. when high noise and shading levels in an image are present or images vary in their characteristics due to different acquisition conditions. Parameters are required to be tuned simultaneously. We propose a framework to improve standard image segmentation methods by using feedback-based automatic parameter adaptation. Moreover, we compare algorithms by implementing them in a feedforward fashion and then adapting their parameters. This comparison is proposed to be evaluated by a benchmark data set that contains challenging image distortions in an increasing fashion. This promptly enables us to compare different standard image segmentation algorithms in a feedback vs. feedforward implementation by evaluating their segmentation quality and robustness. We also propose an efficient way of performing automatic image analysis when only abstract ground truth is present. Such a framework evaluates robustness of different image processing pipelines using a graded data set. This is useful for both end-users and experts. PMID:27764213

  6. A New Feedback-Based Method for Parameter Adaptation in Image Processing Routines.

    PubMed

    Khan, Arif Ul Maula; Mikut, Ralf; Reischl, Markus

    2016-01-01

    The parametrization of automatic image processing routines is time-consuming if a lot of image processing parameters are involved. An expert can tune parameters sequentially to get desired results. This may not be productive for applications with difficult image analysis tasks, e.g. when high noise and shading levels in an image are present or images vary in their characteristics due to different acquisition conditions. Parameters are required to be tuned simultaneously. We propose a framework to improve standard image segmentation methods by using feedback-based automatic parameter adaptation. Moreover, we compare algorithms by implementing them in a feedforward fashion and then adapting their parameters. This comparison is proposed to be evaluated by a benchmark data set that contains challenging image distortions in an increasing fashion. This promptly enables us to compare different standard image segmentation algorithms in a feedback vs. feedforward implementation by evaluating their segmentation quality and robustness. We also propose an efficient way of performing automatic image analysis when only abstract ground truth is present. Such a framework evaluates robustness of different image processing pipelines using a graded data set. This is useful for both end-users and experts.

  7. Adaptive Classification of Landscape Process and Function: An Integration of Geoinformatics and Self-Organizing Maps

    SciTech Connect

    Coleman, Andre M.

    2009-07-17

    The advanced geospatial information extraction and analysis capabilities of a Geographic Information System (GISs) and Artificial Neural Networks (ANNs), particularly Self-Organizing Maps (SOMs), provide a topology-preserving means for reducing and understanding complex data relationships in the landscape. The Adaptive Landscape Classification Procedure (ALCP) is presented as an adaptive and evolutionary capability where varying types of data can be assimilated to address different management needs such as hydrologic response, erosion potential, habitat structure, instrumentation placement, and various forecast or what-if scenarios. This paper defines how the evaluation and analysis of spatial and/or temporal patterns in the landscape can provide insight into complex ecological, hydrological, climatic, and other natural and anthropogenic-influenced processes. Establishing relationships among high-dimensional datasets through neurocomputing based pattern recognition methods can help 1) resolve large volumes of data into a structured and meaningful form; 2) provide an approach for inferring landscape processes in areas that have limited data available but exhibit similar landscape characteristics; and 3) discover the value of individual variables or groups of variables that contribute to specific processes in the landscape. Classification of hydrologic patterns in the landscape is demonstrated.

  8. Simulation of the Cooling of a Semi-Crystalline Polymer in the Injection Molding Process Including PVT Behavior

    NASA Astrophysics Data System (ADS)

    Brahmia, Nadia; Zinet, Matthieu; Boutaous, M'hamed; Chantrenne, Patrice; Bourgin, Patrick; Garcia, David

    2007-05-01

    Accurate numerical simulation of the injection molding process requires a good comprehension of the cooling and solidification phase. In the case of semi-crystalline polymers, this task is complicated because of a strong coupling between heat transfer, crystallization and material compressibility effects. In this work, we carry out the thermophysical characterization of a semi-crystalline polymer (isotactic polypropylene), including the pressure-volume-temperature (PVT) behavior. Then we present a model of the isochoric cooling of this polymer, taking into account these couplings. This model enables us to compute the evolution of pressure, temperature, relative crystallinity and local specific volume in the mold cavity from high initial pressure down to atmospheric pressure and shrinkage onset.

  9. The trapezius muscle uniquely lacks adaptive process in response to a repeated moderate cognitive stressor.

    PubMed

    Willmann, Magali; Bolmont, Benoît

    2012-01-06

    The aim of this study was to examine the adaptive process of muscular responses in healthy subjects over two repeated exposures to the same moderate cognitive stressor. The electromyographic (EMG) activity of the flexor pollicis brevis, biceps brachii, triceps brachii, trapezius, gastrocnemius and soleus muscles was recorded in 35 males during video-recorded Stroop color-word interference tests. The results showed lower EMG activity in all muscles during the second exposure to the stressful task, but not in the trapezius muscle. These findings could help to the understanding of the role of stressful situations in the development of musculoskeletal disorders.

  10. Situation Awareness Implications of Adaptive Automation of Air Traffic Controller Information Processing Functions

    NASA Technical Reports Server (NTRS)

    Kaber, David B.; McClernon, Christopher K.; Perry, Carlene M.; Segall, Noa

    2004-01-01

    The goal of this research was to define a measure of situation awareness (SA) in an air traffic control (ATC) task and to assess the influence of adaptive automation (AA) of various information processing functions on controller perception, comprehension and projection. The measure was also to serve as a basis for defining and developing an approach to triggering dynamic control allocations, as part of AA, based on controller SA. To achieve these objectives, an enhanced version of an ATC simulation (Multitask (copyright)) was developed for use in two human factors experiments. The simulation captured the basic functions of Terminal Radar Approach Control (TRACON) and was capable of presenting to operators four different modes of control, including information acquisition, information analysis, decision making and action implementation automation, as well as a completely manual control mode. The SA measure that was developed as part of the research was based on the Situation Awareness Global Assessment Technique (SAGAT), previous goal-directed task analyses of enroute control and TRACON, and a separate cognitive task analysis on the ATC simulation. The results of the analysis on Multitask were used as a basis for formulating SA queries as part of the SAGAT-based approach to measuring controller SA, which was used in the experiments. A total of 16 subjects were recruited for both experiments. Half the subjects were used in Experiment #1, which focused on assessing the sensitivity and reliability of the SA measurement approach in the ATC simulation. Comparisons were made of manual versus automated control. The remaining subjects were used in the second experiment, which was intended to more completely describe the SA implications of AA applied to specific controller information processing functions, and to describe how the measure could ultimately serve as a trigger of dynamic function allocations in the application of AA to ATC. Comparisons were made of the

  11. An integrated biodesulfurization process, including inoculum preparation, desulfurization and sulfate removal in a single step, for removing sulfur from oils.

    SciTech Connect

    Tangaromsuk, Jantana; Borole, Abhijeet P; Kruatrachue, Maleeya; Pokethitiyook, Prayad

    2008-01-01

    BACKGROUND: A single-stage reactor, in which the growth of bacterial culture, induction of desulfurizing enzymes, and desulfurization reaction are carried out in a single step, was adopted to investigate desulfurization of DBT at high cell densities. IGTS8 was used as the biocatalyst. Optimal condition for the bacterial growth and DBT desulfurization were also investigated. RESULTS: Optimization of fermentation conditions was necessary to obtain high cell densities including controlling accumulation of acetate. Under optimal operating conditions, the maximum OD600 was measured to be 26.6 at 118 h of cultivation. When biodesulfurization of DBT in model oil with a high cell density culture of IGTS8 was investigated, accumulation of sulfate was found to limit the extent of desulfurization. A sulfate removal step was added to obtain a single-stage integrated biodesulfurization process. Sulfate removal was achieved via an aqueous bleed stream and use of a separation unit to recycle the organic phase. CONCLUSION : A proof of principle of a complete system capable of biocatalyst growth, induction, desulfurization and by-product separation was demonstrated. This system enables simplification of the biodesulfurization process and has potential to lower the operating cost of the bioprocess.

  12. Anthocyanin and flavonoid production from Perilla frutescens: pilot plant scale processing including cross-flow microfiltration and reverse osmosis.

    PubMed

    Meng, Linghua; Lozano, Yves; Bombarda, Isabelle; Gaydou, Emile; Li, Bin

    2006-06-14

    Extraction and concentration at a pilot plant scale of anthocyanins and flavonoids from Perilla frutescens var. frutescens harvested in the Guangzhou area of China were investigated. The study of extraction efficiency using mineral acids and organic acids showed that 0.01 mol/L nitric acid was the most suitable to extract flavonoids from this slightly red leaf cultivar. The red extract contained 12 mg/L (as cyanidin equivalent) anthocyanins and other flavones. The multistep process included cross-flow microfiltration (CFM) with a ceramic type membrane, reverse osmosis (RO), and rotating evaporation (RE). The filtration fluxes were high and constant for CFM (150 L/h/m2 at 0.6 b) and for RO (22 L/h/m2 at 40 b). The red extract was concentrated 9.4 times by RO and then 5.4 times by RE. It contained 422 mg/L anthocyanins, representing 77% of the total extracted anthocyanin. The proportion of flavonoids was found unchanged during processing. The concentrated extract showed a pH of 2.7, and its free acidity was found to be 46% of the acidity added for extraction, because of the buffering capacity of the extract. At the concentration level reached, a crystallized deposit occurred and was identified as tartrate.

  13. Evaluating the Adaptation Process of Sandfly Fauna to Anthropized Environments in a Leishmaniasis Transmission Area in the Brazilian Amazon.

    PubMed

    Rosário, Ingrid N G; Andrade, Andrey J; Ligeiro, Raphael; Ishak, Ricardo; Silva, Ivoneide M

    2016-12-22

    Phlebotomines (Diptera: Psychodidae) are vectors of several etiological agents of human and animal diseases, including protozoans of the gender Leishmania Precarious socioeconomic conditions and uncontrolled population growth directly influence the transmission risk of parasites and the urbanization of vector species, previously restricted to wild environments. The Marajó Archipelago is considered a high incidence area of leishmaniasis in the Brazilian Amazon. However, it is poorly studied. The aim of this study was to assess the adaptation processes of phlebotomine species to anthropized environments in this region. For this purpose, the phlebotomine fauna was compared between three municipalities of the Marajó Archipelago: Anajás, Portel, and São Sebastião da Boa Vista. To survey the phlebotomine fauna, CDC (Center for Disease Control) light traps were installed in the wild areas and in the intra and peridomiciliary areas of rural and urban environments. The environments studied presented a diversified phlebotomine fauna, with higher richness in the wild environment (15 species), followed by the rural (seven species), and finally, the urban environment (three species). A migration of wild fauna to the adjacent anthropized areas (rural environment) and to urban areas was observed, evidencing the adaptation process of this vector to anthropized environments in the studied region. Thus, our study evidenced that the disorganized human occupation and utilization of the landscape might cause the invasion of urban areas by wild populations of phlebotomines, in this way enabling the settlement of urban leishmaniasis transmission cycles.

  14. 40 CFR Appendix A to Part 419 - Processes Included in the Determination of BAT Effluent Limitations for Total Chromium...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., and Phenolic Compounds (4AAP) Crude Processes 1. Atmospheric Crude Distillation 2. Crude Desalting 3. Vacuum Crude Distillation Cracking and Coking Processes 4. Visbreaking 5. Thermal Cracking 6....

  15. 40 CFR Appendix A to Part 419 - Processes Included in the Determination of BAT Effluent Limitations for Total Chromium...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., and Phenolic Compounds (4AAP) Crude Processes 1. Atmospheric Crude Distillation 2. Crude Desalting 3. Vacuum Crude Distillation Cracking and Coking Processes 4. Visbreaking 5. Thermal Cracking 6....

  16. 40 CFR Appendix A to Part 419 - Processes Included in the Determination of BAT Effluent Limitations for Total Chromium...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., and Phenolic Compounds (4AAP) Crude Processes 1. Atmospheric Crude Distillation 2. Crude Desalting 3. Vacuum Crude Distillation Cracking and Coking Processes 4. Visbreaking 5. Thermal Cracking 6....

  17. 40 CFR Appendix A to Part 419 - Processes Included in the Determination of BAT Effluent Limitations for Total Chromium...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., and Phenolic Compounds (4AAP) Crude Processes 1. Atmospheric Crude Distillation 2. Crude Desalting 3. Vacuum Crude Distillation Cracking and Coking Processes 4. Visbreaking 5. Thermal Cracking 6....

  18. Established and Adapted Diagnostic Tools for Investigation of a Special Twin-Wire Arc Spraying Process

    NASA Astrophysics Data System (ADS)

    König, Johannes; Lahres, Michael; Zimmermann, Stephan; Schein, Jochen

    2016-10-01

    In the LDS® ( Lichtbogendrahtspritzen) process, a twin-wire arc spraying (TWAS) process developed by Daimler AG, the gas injection and feed to the arc play a crucial role in separating the molten particles from the wire ends. This paper describes an investigation of the gas and particle behavior according to individual LDS® process parameters. Coating problems are not considered. The measurements are separated into two different parts: "cold" (without arc and particles) and "hot" (with arc and particles). The results provide the first detailed understanding of the effect of different LDS® process parameters. A correlation between the gas parameter settings and the particle beam properties was found. Using established and adapted diagnostic tools, as also applied for conventional TWAS processes, this special LDS® process was investigated and the results (gas and particle behavior) validated, thereby allowing explanation and comparison of the diagnostic methods, which is the main focus of this paper. Based on error analysis, individual instabilities, limits, and deviations during the gas determinations and particle measurements are explained in more detail. The paper concludes with presentation of the first particle-shadow diagnostic results and main statements regarding these investigations.

  19. Workload-Matched Adaptive Automation Support of Air Traffic Controller Information Processing Stages

    NASA Technical Reports Server (NTRS)

    Kaber, David B.; Prinzel, Lawrence J., III; Wright, Melanie C.; Clamann, Michael P.

    2002-01-01

    Adaptive automation (AA) has been explored as a solution to the problems associated with human-automation interaction in supervisory control environments. However, research has focused on the performance effects of dynamic control allocations of early stage sensory and information acquisition functions. The present research compares the effects of AA to the entire range of information processing stages of human operators, such as air traffic controllers. The results provide evidence that the effectiveness of AA is dependent on the stage of task performance (human-machine system information processing) that is flexibly automated. The results suggest that humans are better able to adapt to AA when applied to lower-level sensory and psychomotor functions, such as information acquisition and action implementation, as compared to AA applied to cognitive (analysis and decision-making) tasks. The results also provide support for the use of AA, as compared to completely manual control. These results are discussed in terms of implications for AA design for aviation.

  20. [Super sweet corn hybrid sh2 adaptability for industrial canning process].

    PubMed

    Ortiz de Bertorelli, Ligia; De Venanzi, Frank; Alfonzo, Braunnier; Camacho, Candelario

    2002-12-01

    The super sweet corns Krispy king, Victor and 324 (sh2 hybrids) were evaluated to determine their adaptabilities to the industrial canning process as whole kernels. All these hybrids and Bonanza (control) were sown in San Joaquín (Carabobo, Venezuela), harvested and canned. After 110 days storage at room temperature they were analyzed to be compared physically, chemically and sensorially with Bonanza hybrid. Results did not show significant differences among most of the physical characteristics, except for percentage of broken kernels which was higher in 324 hybrid. Chemical parameters showed significant differences (P < 0.05) comparing each super sweet hybrid with Bonanza. The super sweet hybrids presented a higher sugar content and soluble solid of the brine than Bonanza, also a lower pH. The super sweet whole kernel presented a lower soluble solids content than Bonanza but they were not significant (Krispy king and 324). Appearance, odor and overall quality were the same for super sweet hybrids and Bonanza (su). Color, flavor and sweetness were better for 324 than all the other hybrids. Super sweet hybrids presented a very good adaptation to the canning process, having as an advantage that doesn't require sugar addition in the brine and a very good texture (firm and crispy).

  1. Modelling of adaptation processes of crops to water and nitrogen stress

    NASA Astrophysics Data System (ADS)

    Kovács, Géza J.

    In the early 1980s the author published interpretations of his observations on special adaptation processes of crops (“Zichy” experiment). Those days it was not yet possible to include these details into a crop model. The knowledge has grown about the systems of crops and their environment, now it is appropriate to test those hypothesis by systems models. The 4M system model used in this study was developed by RISSAC modelling team lead by the author. 4M is based on CERES model family and the advices of the “father” of CERES, J.T. Ritchie. 4M aims to include a lot of results from Hungarian agricultural research. Some observations of “Zichy” experiment needed explanations but there were shortages of information on some parts of the system in order to test the hypothesis. Observations were as it follows: (1) The growth of above ground maize biomass slowed down in both years after a heavy rainy period. (2) Following the rainy period there was a fast drop of nitrate content in the soil and (3) following this time the water content of soil decreased with a fast rate approaching the wilting point. (4) When maize reacted on the emerging water stress there was a second (and even deeper) slow down of growth of above ground biomass. (5) The consequences of the stormy period was more dramatic in the second year of the experiment (1979), there was 3 t ha -1 loss of biomass and 2.5 t ha -1 loss of grain yield relative to 1978. (6) There was a significant difference in the time of stormy rain: in 1978 it occurred post-anthesis while in 1979 it occurred just prior to anthesis. Hypothesis tested here were as it follows: (1) The cause of observed growth stress reaction was a fast nitrate leaching from the rooted zone. (2) The crops cannot take up all the mineral nitrogen measured in a soil probe, the major limit is the mass flow to the roots controlled by transpiration and nitrogen concentration of soil solution. (3) “Leaching of soil by a flush of rain leads to

  2. Active learning: effects of core training design elements on self-regulatory processes, learning, and adaptability.

    PubMed

    Bell, Bradford S; Kozlowski, Steve W J

    2008-03-01

    This article describes a comprehensive examination of the cognitive, motivational, and emotional processes underlying active learning approaches; their effects on learning and transfer; and the core training design elements (exploration, training frame, emotion control) and individual differences (cognitive ability, trait goal orientation, trait anxiety) that shape these processes. Participants (N = 350) were trained to operate a complex, computer-based simulation. Exploratory learning and error-encouragement framing had a positive effect on adaptive transfer performance and interacted with cognitive ability and dispositional goal orientation to influence trainees' metacognition and state goal orientation. Trainees who received the emotion-control strategy had lower levels of state anxiety. Implications for development of an integrated theory of active learning, learner-centered design, and research extensions are discussed.

  3. Remaining useful life prediction for an adaptive skew-Wiener process model

    NASA Astrophysics Data System (ADS)

    Huang, Zeyi; Xu, Zhengguo; Ke, Xiaojie; Wang, Wenhai; Sun, Youxian

    2017-03-01

    Predicting the remaining useful life for operational devices plays a critical role in prognostics and health management. As the models based on the stochastic processes are widely used for characterizing the degradation trajectory, an adaptive skew-Wiener model, which is much more flexible than traditional stochastic process models, is proposed to model the degradation drift of industrial devices. To make full use of the prior knowledge and the historical information, an on-line filtering algorithm is proposed for state estimation, a two-stage algorithm is adopted to estimate unknown parameters as well. For remaining useful life prediction, a novel result is presented with an explicit form based on the closed skew normal distribution. Finally, sufficient Monte Carlo simulations and an application for ball bearings in rotating electrical machines are used to validate our approach.

  4. Automatic ultrasonic imaging system with adaptive-learning-network signal-processing techniques

    SciTech Connect

    O'Brien, L.J.; Aravanis, N.A.; Gouge, J.R. Jr.; Mucciardi, A.N.; Lemon, D.K.; Skorpik, J.R.

    1982-04-01

    A conventional pulse-echo imaging system has been modified to operate with a linear ultrasonic array and associated digital electronics to collect data from a series of defects fabricated in aircraft quality steel blocks. A thorough analysis of the defect responses recorded with this modified system has shown that considerable improvements over conventional imaging approaches can be obtained in the crucial areas of defect detection and characterization. A combination of advanced signal processing concepts with the Adaptive Learning Network (ALN) methodology forms the basis for these improvements. Use of established signal processing algorithms such as temporal and spatial beam-forming in concert with a sophisticated detector has provided a reliable defect detection scheme which can be implemented in a microprocessor-based system to operate in an automatic mode.

  5. Adaptive and repeated cumulative meta-analyses of safety data during a new drug development process.

    PubMed

    Quan, Hui; Ma, Yingqiu; Zheng, Yan; Cho, Meehyung; Lorenzato, Christelle; Hecquet, Carole

    2015-01-01

    During a new drug development process, it is desirable to timely detect potential safety signals. For this purpose, repeated meta-analyses may be performed sequentially on accumulating safety data. Moreover, if the amount of safety data from the originally planned program is not enough to ensure adequate power to test a specific hypothesis (e.g., the noninferiority hypothesis of an event of interest), the total sample size may be increased by adding new studies to the program. Without appropriate adjustment, it is well known that the type I error rate will be inflated because of repeated analyses and sample size adjustment. In this paper, we discuss potential issues associated with adaptive and repeated cumulative meta-analyses of safety data conducted during a drug development process. We consider both frequentist and Bayesian approaches. A new drug development example is used to demonstrate the application of the methods.

  6. Combining molecular evolution and environmental genomics to unravel adaptive processes of MHC class IIB diversity in European minnows (Phoxinus phoxinus)

    PubMed Central

    Collin, Helene; Burri, Reto; Comtesse, Fabien; Fumagalli, Luca

    2013-01-01

    Abstract Host–pathogen interactions are a major evolutionary force promoting local adaptation. Genes of the major histocompatibility complex (MHC) represent unique candidates to investigate evolutionary processes driving local adaptation to parasite communities. The present study aimed at identifying the relative roles of neutral and adaptive processes driving the evolution of MHC class IIB (MHCIIB) genes in natural populations of European minnows (Phoxinus phoxinus). To this end, we isolated and genotyped exon 2 of two MHCIIB gene duplicates (DAB1 and DAB3) and 1′665 amplified fragment length polymorphism (AFLP) markers in nine populations, and characterized local bacterial communities by 16S rDNA barcoding using 454 amplicon sequencing. Both MHCIIB loci exhibited signs of historical balancing selection. Whereas genetic differentiation exceeded that of neutral markers at both loci, the populations' genetic diversities were positively correlated with local pathogen diversities only at DAB3. Overall, our results suggest pathogen-mediated local adaptation in European minnows at both MHCIIB loci. While at DAB1 selection appears to favor different alleles among populations, this is only partially the case in DAB3, which appears to be locally adapted to pathogen communities in terms of genetic diversity. These results provide new insights into the importance of host–pathogen interactions in driving local adaptation in the European minnow, and highlight that the importance of adaptive processes driving MHCIIB gene evolution may differ among duplicates within species, presumably as a consequence of alternative selective regimes or different genomic context. Using next-generation sequencing, the present manuscript identifies the relative roles of neutral and adaptive processes driving the evolution of MHC class IIB (MHCIIB) genes in natural populations of a cyprinid fish: the European minnow (Phoxinus phoxinus). We highlight that the relative importance of neutral

  7. Health-related quality of life and adaptive behaviors of adolescents with sickle cell disease: stress processing moderators.

    PubMed

    Ziadni, Maisa S; Patterson, Chavis A; Pulgarón, Elizabeth R; Robinson, M Renée; Barakat, Lamia P

    2011-12-01

    The objective of this study was to examine resilience among adolescents with sickle cell disease (SCD), focusing on the interaction of health-related quality of life with stress processing to explain adaptive behavior. Forty-four adolescents with SCD completed paper-and-pencil measures of health-related quality of life, appraisals (hope), pain coping strategies (e.g. adherence), and adaptive behavior. Self-reported health-related quality of life was significantly associated with adaptive behavior, as was adherence. Findings for moderation were mixed. Pain coping strategies moderated the association of health-related quality of life with adaptive behavior such that at lower levels of Coping Strategies Questionnaire (CSQ) Adherence, better quality of life was associated with higher adaptive behavior. Similarly, at higher levels of hope, better quality of life was associated with higher adaptive behavior, and poorer quality of life was associated with lower adaptive behavior. Adolescents with SCD showed resilience, particularly in terms of personal adjustment, that may be explained by their appraisals and stress processing strategies. Interventions to support an optimistic or hopeful outlook and improve adherence to recommendations for medical management of sickle cell pain may result in improved resilience/adaptive behavior.

  8. The Process of Adaptation of a Community-Level, Evidence-Based Intervention for HIV-Positive African American Men Who Have Sex with Men in Two Cities

    ERIC Educational Resources Information Center

    Robinson, Beatrice E.; Galbraith, Jennifer S.; Lund, Sharon M.; Hamilton, Autumn R.; Shankle, Michael D.

    2012-01-01

    We describe the process of adapting a community-level, evidence-based behavioral intervention (EBI), Community PROMISE, for HIV-positive African American men who have sex with men (AAMSM). The Centers for Disease Control and Prevention (CDC) Map of the Adaptation Process (MAP) guided the adaptation process for this new target population by two…

  9. 40 CFR Appendix A to Part 419 - Processes Included in the Determination of BAT Effluent Limitations for Total Chromium...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., Hexavalent Chromium, and Phenolic Compounds (4AAP) Crude Processes 1. Atmospheric Crude Distillation 2. Crude Desalting 3. Vacuum Crude Distillation Cracking and Coking Processes 4. Visbreaking 5. Thermal Cracking...

  10. Adaptive algorithms of position and energy reconstruction in Anger-camera type detectors: experimental data processing in ANTS

    NASA Astrophysics Data System (ADS)

    Morozov, A.; Defendi, I.; Engels, R.; Fraga, F. A. F.; Fraga, M. M. F. R.; Gongadze, A.; Guerard, B.; Jurkovic, M.; Kemmerling, G.; Manzin, G.; Margato, L. M. S.; Niko, H.; Pereira, L.; Petrillo, C.; Peyaud, A.; Piscitelli, F.; Raspino, D.; Rhodes, N. J.; Sacchetti, F.; Schooneveld, E. M.; Solovov, V.; Van Esch, P.; Zeitelhack, K.

    2013-05-01

    The software package ANTS (Anger-camera type Neutron detector: Toolkit for Simulations), developed for simulation of Anger-type gaseous detectors for thermal neutron imaging was extended to include a module for experimental data processing. Data recorded with a sensor array containing up to 100 photomultiplier tubes (PMT) or silicon photomultipliers (SiPM) in a custom configuration can be loaded and the positions and energies of the events can be reconstructed using the Center-of-Gravity, Maximum Likelihood or Least Squares algorithm. A particular strength of the new module is the ability to reconstruct the light response functions and relative gains of the photomultipliers from flood field illumination data using adaptive algorithms. The performance of the module is demonstrated with simulated data generated in ANTS and experimental data recorded with a 19 PMT neutron detector. The package executables are publicly available at http://coimbra.lip.pt/~andrei/

  11. The SEB-1 Transcription Factor Binds to the STRE Motif in Neurospora crassa and Regulates a Variety of Cellular Processes Including the Stress Response and Reserve Carbohydrate Metabolism

    PubMed Central

    Freitas, Fernanda Zanolli; Virgilio, Stela; Cupertino, Fernanda Barbosa; Kowbel, David John; Fioramonte, Mariana; Gozzo, Fabio Cesar; Glass, N. Louise; Bertolini, Maria Célia

    2016-01-01

    When exposed to stress conditions, all cells induce mechanisms resulting in an attempt to adapt to stress that involve proteins which, once activated, trigger cell responses by modulating specific signaling pathways. In this work, using a combination of pulldown assays and mass spectrometry analyses, we identified the Neurospora crassa SEB-1 transcription factor that binds to the Stress Response Element (STRE) under heat stress. Orthologs of SEB-1 have been functionally characterized in a few filamentous fungi as being involved in stress responses; however, the molecular mechanisms mediated by this transcription factor may not be conserved. Here, we provide evidences for the involvement of N. crassa SEB-1 in multiple cellular processes, including response to heat, as well as osmotic and oxidative stress. The Δseb-1 strain displayed reduced growth under these conditions, and genes encoding stress-responsive proteins were differentially regulated in the Δseb-1 strain grown under the same conditions. In addition, the SEB-1-GFP protein translocated from the cytosol to the nucleus under heat, osmotic, and oxidative stress conditions. SEB-1 also regulates the metabolism of the reserve carbohydrates glycogen and trehalose under heat stress, suggesting an interconnection between metabolism control and this environmental condition. We demonstrated that SEB-1 binds in vivo to the promoters of genes encoding glycogen metabolism enzymes and regulates their expression. A genome-wide transcriptional profile of the Δseb-1 strain under heat stress was determined by RNA-seq, and a broad range of cellular processes was identified that suggests a role for SEB-1 as a protein interconnecting these mechanisms. PMID:26994287

  12. Adaptive Sensor Optimization and Cognitive Image Processing Using Autonomous Optical Neuroprocessors

    SciTech Connect

    CAMERON, STEWART M.

    2001-10-01

    Measurement and signal intelligence demands has created new requirements for information management and interoperability as they affect surveillance and situational awareness. Integration of on-board autonomous learning and adaptive control structures within a remote sensing platform architecture would substantially improve the utility of intelligence collection by facilitating real-time optimization of measurement parameters for variable field conditions. A problem faced by conventional digital implementations of intelligent systems is the conflict between a distributed parallel structure on a sequential serial interface functionally degrading bandwidth and response time. In contrast, optically designed networks exhibit the massive parallelism and interconnect density needed to perform complex cognitive functions within a dynamic asynchronous environment. Recently, all-optical self-organizing neural networks exhibiting emergent collective behavior which mimic perception, recognition, association, and contemplative learning have been realized using photorefractive holography in combination with sensory systems for feature maps, threshold decomposition, image enhancement, and nonlinear matched filters. Such hybrid information processors depart from the classical computational paradigm based on analytic rules-based algorithms and instead utilize unsupervised generalization and perceptron-like exploratory or improvisational behaviors to evolve toward optimized solutions. These systems are robust to instrumental systematics or corrupting noise and can enrich knowledge structures by allowing competition between multiple hypotheses. This property enables them to rapidly adapt or self-compensate for dynamic or imprecise conditions which would be unstable using conventional linear control models. By incorporating an intelligent optical neuroprocessor in the back plane of an imaging sensor, a broad class of high-level cognitive image analysis problems including geometric

  13. Inside the adaptation process of Lactobacillus delbrueckii subsp. lactis to bile.

    PubMed

    Burns, Patricia; Sánchez, Borja; Vinderola, Gabriel; Ruas-Madiedo, Patricia; Ruiz, Lorena; Margolles, Abelardo; Reinheimer, Jorge; de los Reyes-Gavilán, Clara G

    2010-08-15

    Progressive adaptation to bile might render some lactobacilli able to withstand physiological bile salt concentrations. In this work, the adaptation to bile was evaluated on previously isolated dairy strains of Lactobacillus delbrueckii subsp. lactis 200 and L. delbrueckii subsp. lactis 200+, a strain derived thereof with stable bile-resistant phenotype. The adaptation to bile was obtained by comparing cytosolic proteomes of both strains grown in the presence or absence of bile. Proteomics were complemented with physiological studies on both strains focusing on glycolytic end-products, the ability to adhere to the human intestinal epithelial cell line HT29-MTX and survival to simulated gastrointestinal conditions. Protein pattern comparison of strains grown with and without bile allowed us to identify 9 different proteins whose production was regulated by bile in both strains, and 17 proteins that showed differences in their levels between the parental and the bile-resistant derivative. These included general stress response chaperones, proteins involved in transcription and translation, in peptidoglycan/exopolysaccharide biosynthesis, in the lipid and nucleotide metabolism and several glycolytic and pyruvate catabolism enzymes. Differences in the level of metabolic end-products of the sugar catabolism were found between the strains 200 and 200+. A decrease in the adhesion of both strains to the intestinal cell line was detected in the presence of bile. In simulated gastric and intestinal juices, a protective effect was exerted by milk improving the survival of both microorganisms. These results indicate that bile tolerance in L. delbrueckii subsp. lactis involves several mechanisms responding to the deleterious impact of bile salts on bacterial physiology.

  14. Adaptive sidelobe reduction in SAR and INSAR COSMO-SkyMed image processing

    NASA Astrophysics Data System (ADS)

    Lorusso, Rino; Lombardi, Nunzia; Milillo, Giovanni

    2016-10-01

    The main lobe and the side lobes of strong scatterers are sometimes clearly visible in SAR images. Sidelobe reduction is of particular importance when imaging scenes contain objects such as ships and buildings having very large radar cross sections. Amplitude weighting is usually used to suppress sidelobes of the images at the expense of broadening of mainlobe, loss of resolution and degradation of SAR images. The Spatial Variant Apodization (SVA) is an Adaptive SideLobe Reduction (ASLR) technique that provides high effective suppression of sidelobes without broadening mainlobe. In this paper, we apply SVA to process COSMO-SkyMed (CSK) StripMap and Spotlight X-band data and compare the images with the standard products obtained via Hamming window processing. Different test sites have been selected in Italy, Argentina, California and Germany where corner reflectors are installed. Experimental results show clearly the resolution improvement (20%) while sidelobe kept to a low level when SVA processing is applied compared with Hamming windowing one. Then SVA technique is applied to Interferometric SAR image processing (INSAR) using a CSK StripMap interferometric tandem-like data pair acquired on East-California. The interferometric coherence of image pair obtained without sidelobe reduction (SCS_U) and with sidelobe reduction performed via Hamming window and via SVA are compared. High resolution interferometric products have been obtained with small variation of mean coherence when using ASLR products with respect to hamming windowed and no windowed one.

  15. Adaptive memory: Survival processing increases both true and false memory in adults and children.

    PubMed

    Otgaar, Henry; Smeets, Tom

    2010-07-01

    Research has shown that processing information in a survival context can enhance the information's memorability. The current study examined whether survival processing can also decrease the susceptibility to false memories and whether the survival advantage can be found in children. In Experiment 1, adults rated semantically related words in a survival, moving, or pleasantness scenario. Even though the survival advantage was demonstrated for true recall, there also was an unexpected increase in false memories in the survival condition. Similarly, younger and older children in Experiment 2 displayed superior true recall but also higher rates of false memories in a survival condition. Experiment 3 showed that in adults false memories were also more likely to occur in the survival condition when categorized lists instead of Deese-Roediger-McDermott (DRM)-like word lists were used. In all three experiments, no survival recall advantage was found when net accuracy scores that take the total output into account were used. These findings question whether survival processing is an adaptive memory strategy per se, as such processing not only enriches true recall but simultaneously amplifies the vulnerability to false memories.

  16. Intelligent Modeling Combining Adaptive Neuro Fuzzy Inference System and Genetic Algorithm for Optimizing Welding Process Parameters

    NASA Astrophysics Data System (ADS)

    Gowtham, K. N.; Vasudevan, M.; Maduraimuthu, V.; Jayakumar, T.

    2011-04-01

    Modified 9Cr-1Mo ferritic steel is used as a structural material for steam generator components of power plants. Generally, tungsten inert gas (TIG) welding is preferred for welding of these steels in which the depth of penetration achievable during autogenous welding is limited. Therefore, activated flux TIG (A-TIG) welding, a novel welding technique, has been developed in-house to increase the depth of penetration. In modified 9Cr-1Mo steel joints produced by the A-TIG welding process, weld bead width, depth of penetration, and heat-affected zone (HAZ) width play an important role in determining the mechanical properties as well as the performance of the weld joints during service. To obtain the desired weld bead geometry and HAZ width, it becomes important to set the welding process parameters. In this work, adaptative neuro fuzzy inference system is used to develop independent models correlating the welding process parameters like current, voltage, and torch speed with weld bead shape parameters like depth of penetration, bead width, and HAZ width. Then a genetic algorithm is employed to determine the optimum A-TIG welding process parameters to obtain the desired weld bead shape parameters and HAZ width.

  17. Adapting a memory framework (source monitoring) to the study of closure processes.

    PubMed

    Foley, Mary Ann; Foley, Hugh J; Korenman, Lisa M

    2002-04-01

    The present experiments adapt a memory framework (source monitoring) to the study of closure processes. Closure processes are invoked as explanatory mechanisms underlying the ability to identify objects under conditions of incomplete visual information. If closure processes are activated, filling in missing pieces of visual information, intriguing memory predictions follow. When making source judgments about the way in which visual information was experienced initially (e.g., complete or incomplete in form), a particular kind of memory error should be evident. Incomplete visual information should be remembered as complete in form, and indeed, this error is observed. The present experiments test alternative interpretations for the initial reports of this memory error in the context of a search task modeled after the Where's Waldo? children's books. The effects of several new factors (e.g., familiarity) are reported, and alternative interpretations for the bias to report complete are eliminated. Findings, therefore, have implications for understanding the mechanisms of closure processes, as well as for the source-monitoring framework itself.

  18. Simulation of metal forming processes with a 3D adaptive remeshing procedure

    NASA Astrophysics Data System (ADS)

    Zeramdini, Bessam; Robert, Camille; Germain, Guenael; Pottier, Thomas

    2016-10-01

    In this paper, a fully adaptive 3D numerical methodology based on a tetrahedral element was proposed in order to improve the finite element simulation of any metal forming process. This automatic methodology was implemented in a computational platform which integrates a finite element solver, 3D mesh generation and a field transfer algorithm. The proposed remeshing method was developed in order to solve problems associated with the severe distortion of elements subject to large deformations, to concentrate the elements where the error is large and to coarsen the mesh where the error is small. This leads to a significant reduction in the computation times while maintaining simulation accuracy. In addition, in order to enhance the contact conditions, this method has been coupled with a specific operator to maintain the initial contact between the workpiece nodes and the rigid tool after each remeshing step. In this paper special attention is paid to the data transfer methods and the necessary adaptive remeshing steps are given. Finally, a numerical example is detailed to demonstrate the efficiency of the approach and to compare the results for the different field transfer strategies.

  19. An adaptive threshold based image processing technique for improved glaucoma detection and classification.

    PubMed

    Issac, Ashish; Partha Sarathi, M; Dutta, Malay Kishore

    2015-11-01

    Glaucoma is an optic neuropathy which is one of the main causes of permanent blindness worldwide. This paper presents an automatic image processing based method for detection of glaucoma from the digital fundus images. In this proposed work, the discriminatory parameters of glaucoma infection, such as cup to disc ratio (CDR), neuro retinal rim (NRR) area and blood vessels in different regions of the optic disc has been used as features and fed as inputs to learning algorithms for glaucoma diagnosis. These features which have discriminatory changes with the occurrence of glaucoma are strategically used for training the classifiers to improve the accuracy of identification. The segmentation of optic disc and cup based on adaptive threshold of the pixel intensities lying in the optic nerve head region. Unlike existing methods the proposed algorithm is based on an adaptive threshold that uses local features from the fundus image for segmentation of optic cup and optic disc making it invariant to the quality of the image and noise content which may find wider acceptability. The experimental results indicate that such features are more significant in comparison to the statistical or textural features as considered in existing works. The proposed work achieves an accuracy of 94.11% with a sensitivity of 100%. A comparison of the proposed work with the existing methods indicates that the proposed approach has improved accuracy of classification glaucoma from a digital fundus which may be considered clinically significant.

  20. GAMER: A GRAPHIC PROCESSING UNIT ACCELERATED ADAPTIVE-MESH-REFINEMENT CODE FOR ASTROPHYSICS

    SciTech Connect

    Schive, H.-Y.; Tsai, Y.-C.; Chiueh Tzihong

    2010-02-01

    We present the newly developed code, GPU-accelerated Adaptive-MEsh-Refinement code (GAMER), which adopts a novel approach in improving the performance of adaptive-mesh-refinement (AMR) astrophysical simulations by a large factor with the use of the graphic processing unit (GPU). The AMR implementation is based on a hierarchy of grid patches with an oct-tree data structure. We adopt a three-dimensional relaxing total variation diminishing scheme for the hydrodynamic solver and a multi-level relaxation scheme for the Poisson solver. Both solvers have been implemented in GPU, by which hundreds of patches can be advanced in parallel. The computational overhead associated with the data transfer between the CPU and GPU is carefully reduced by utilizing the capability of asynchronous memory copies in GPU, and the computing time of the ghost-zone values for each patch is diminished by overlapping it with the GPU computations. We demonstrate the accuracy of the code by performing several standard test problems in astrophysics. GAMER is a parallel code that can be run in a multi-GPU cluster system. We measure the performance of the code by performing purely baryonic cosmological simulations in different hardware implementations, in which detailed timing analyses provide comparison between the computations with and without GPU(s) acceleration. Maximum speed-up factors of 12.19 and 10.47 are demonstrated using one GPU with 4096{sup 3} effective resolution and 16 GPUs with 8192{sup 3} effective resolution, respectively.

  1. Usability of clinical decision support system as a facilitator for learning the assistive technology adaptation process.

    PubMed

    Danial-Saad, Alexandra; Kuflik, Tsvi; Weiss, Patrice L Tamar; Schreuer, Naomi

    2016-01-01

    The aim of this study was to evaluate the usability of Ontology Supported Computerized Assistive Technology Recommender (OSCAR), a Clinical Decision Support System (CDSS) for the assistive technology adaptation process, its impact on learning the matching process, and to determine the relationship between its usability and learnability. Two groups of expert and novice clinicians (total, n = 26) took part in this study. Each group filled out system usability scale (SUS) to evaluate OSCAR's usability. The novice group completed a learning questionnaire to assess OSCAR's effect on their ability to learn the matching process. Both groups rated OSCAR's usability as "very good", (M [SUS] = 80.7, SD = 11.6, median = 83.7) by the novices, and (M [SUS] = 81.2, SD = 6.8, median = 81.2) by the experts. The Mann-Whitney results indicated that no significant differences were found between the expert and novice groups in terms of OSCAR's usability. A significant positive correlation existed between the usability of OSCAR and the ability to learn the adaptation process (rs = 0.46, p = 0.04). Usability is an important factor in the acceptance of a system. The successful application of user-centered design principles during the development of OSCAR may serve as a case study that models the significant elements to be considered, theoretically and practically in developing other systems. Implications for Rehabilitation Creating a CDSS with a focus on its usability is an important factor for its acceptance by its users. Successful usability outcomes can impact the learning process of the subject matter in general, and the AT prescription process in particular. The successful application of User-Centered Design principles during the development of OSCAR may serve as a case study that models the significant elements to be considered, theoretically and practically. The study emphasizes the importance of close collaboration between the developers and

  2. Joint Adaptive Pre-processing Resilience and Post-processing Concealment Schemes for 3D Video Transmission

    NASA Astrophysics Data System (ADS)

    El-Shafai, Walid

    2015-03-01

    3D video transmission over erroneous networks is still a considerable issue due to restricted resources and the presence of severe channel errors. Efficiently compressing 3D video with low transmission rate, while maintaining a high quality of received 3D video, is very challenging. Since it is not plausible to re-transmit all the corrupted macro-blocks (MBs) due to real time applications and limited resources. Thus it is mandatory to retrieve the lost MBs at the decoder side using sufficient post-processing schemes, such as error concealment (EC). In this paper, we propose an adaptive multi-mode EC (AMMEC) algorithm at the decoder based on utilizing pre-processing flexible macro-block ordering error resilience (FMO-ER) technique at the encoder; to efficiently conceal the erroneous MBs of intra and inter coded frames of 3D video. Experimental simulation results show that the proposed FMO-ER/AMMEC schemes can significantly improve the objective and subjective 3D video quality.

  3. Competitiveness and the Process of Co-adaptation in Team Sport Performance

    PubMed Central

    Passos, Pedro; Araújo, Duarte; Davids, Keith

    2016-01-01

    An evolutionary psycho-biological perspective on competitiveness dynamics is presented, focusing on continuous behavioral co-adaptations to constraints that arise in performance environments. We suggest that an athlete’s behavioral dynamics are constrained by circumstances of competing for the availability of resources, which once obtained offer possibilities for performance success. This defines the influence of the athlete-environment relationship on competitiveness. Constraining factors in performance include proximity to target areas in team sports and the number of other competitors in a location. By pushing the athlete beyond existing limits, competitiveness enhances opportunities for co-adaptation, innovation and creativity, which can lead individuals toward different performance solutions to achieve the same performance goal. Underpinned by an ecological dynamics framework we examine whether competitiveness is a crucial feature to succeed in team sports. Our focus is on intra-team competitiveness, concerning the capacity of individuals within a team to become perceptually attuned to affordances in a given performance context which can increase their likelihood of success. This conceptualization implies a re-consideration of the concept of competitiveness, not as an inherited trait or entity to be acquired, but rather theorizing it as a functional performer-environment relationship that needs to be explored, developed, enhanced and maintained in team games training programs. PMID:27777565

  4. Analysis and evalaution in the production process and equipment area of the low-cost solar array project. [including modifying gaseous diffusion and using ion implantation

    NASA Technical Reports Server (NTRS)

    Goldman, H.; Wolf, M.

    1979-01-01

    The manufacturing methods for photovoltaic solar energy utilization are assessed. Economic and technical data on the current front junction formation processes of gaseous diffusion and ion implantation are presented. Future proposals, including modifying gaseous diffusion and using ion implantation, to decrease the cost of junction formation are studied. Technology developments in current processes and an economic evaluation of the processes are included.

  5. Nonlinear structural response using adaptive dynamic relaxation on a massively-parallel-processing system

    NASA Technical Reports Server (NTRS)

    Oakley, David R.; Knight, Norman F., Jr.

    1994-01-01

    A parallel adaptive dynamic relaxation (ADR) algorithm has been developed for nonlinear structural analysis. This algorithm has minimal memory requirements, is easily parallelizable and scalable to many processors, and is generally very reliable and efficient for highly nonlinear problems. Performance evaluations on single-processor computers have shown that the ADR algorithm is reliable and highly vectorizable, and that it is competitive with direct solution methods for the highly nonlinear problems considered. The present algorithm is implemented on the 512-processor Intel Touchstone DELTA system at Caltech, and it is designed to minimize the extent and frequency of interprocessor communication. The algorithm has been used to solve for the nonlinear static response of two and three dimensional hyperelastic systems involving contact. Impressive relative speedups have been achieved and demonstrate the high scalability of the ADR algorithm. For the class of problems addressed, the ADR algorithm represents a very promising approach for parallel-vector processing.

  6. Impacts of Climate Change and of Anthropisation on Water Resources: from the Risk Assessment to Adaptation, the Case of the Seine Basin (including Paris, France)

    NASA Astrophysics Data System (ADS)

    Habets, F.; Viennot, P.; Thierion, C.; Vergnes, J. P.; Ait Kaci, A.; Caballero, Y.

    2015-12-01

    The Seine river, located in the temperate climate of northern France and flowing over a large sedimentary basins that hosts multilayer aquifers, is characterized by small temporal variations of its discharge. However, the presence of a megacity (Paris) and a wide area of intensive agriculture combined with climate change puts pressure on the water resources both in terms of quality and quantity. Previous research projects have estimated the impact of climate change on the water resource of the Seine basin, with the uncertainties associated to climate projections, hydrological models or downscaling methods. The water resource was projected to decrease by -14 % ± 10 % in 2050 and -28 +/-16% in 2100. This led to new studies that focus on the combined impact of climate change and adaptations. The tested adaptations are: a reduction of the groundwater abstractions, evolution of land use, development of small dams to « harvest water » or artificial recharge of aquifers. The communication of the results of these projects to stakeholders have led to the development on new indicators that better express the risk on the water resource management, especially for the groundwater. For instance maps of the evolution of piezometric head are difficult to interpret. To better express the risk evolution, a new indicator was defined: the evolution of the groundwater crisis duration, ie, the period when the charge of the aquifer is below the crisis piezometric level defined by the stakeholders. Such crisis piezometric levels are used to help defining the period when the groundwater abstraction should be reduced. Such maps are more efficient to communicate with water resources managers. This communication will focus on the results from the MEDDE Explore 2070 and ANR Oracle projects.

  7. An adaptive process-based cloud infrastructure for space situational awareness applications

    NASA Astrophysics Data System (ADS)

    Liu, Bingwei; Chen, Yu; Shen, Dan; Chen, Genshe; Pham, Khanh; Blasch, Erik; Rubin, Bruce

    2014-06-01

    Space situational awareness (SSA) and defense space control capabilities are top priorities for groups that own or operate man-made spacecraft. Also, with the growing amount of space debris, there is an increase in demand for contextual understanding that necessitates the capability of collecting and processing a vast amount sensor data. Cloud computing, which features scalable and flexible storage and computing services, has been recognized as an ideal candidate that can meet the large data contextual challenges as needed by SSA. Cloud computing consists of physical service providers and middleware virtual machines together with infrastructure, platform, and software as service (IaaS, PaaS, SaaS) models. However, the typical Virtual Machine (VM) abstraction is on a per operating systems basis, which is at too low-level and limits the flexibility of a mission application architecture. In responding to this technical challenge, a novel adaptive process based cloud infrastructure for SSA applications is proposed in this paper. In addition, the details for the design rationale and a prototype is further examined. The SSA Cloud (SSAC) conceptual capability will potentially support space situation monitoring and tracking, object identification, and threat assessment. Lastly, the benefits of a more granular and flexible cloud computing resources allocation are illustrated for data processing and implementation considerations within a representative SSA system environment. We show that the container-based virtualization performs better than hypervisor-based virtualization technology in an SSA scenario.

  8. Design Process of Flight Vehicle Structures for a Common Bulkhead and an MPCV Spacecraft Adapter

    NASA Technical Reports Server (NTRS)

    Aggarwal, Pravin; Hull, Patrick V.

    2015-01-01

    Design and manufacturing space flight vehicle structures is a skillset that has grown considerably at NASA during that last several years. Beginning with the Ares program and followed by the Space Launch System (SLS); in-house designs were produced for both the Upper Stage and the SLS Multipurpose crew vehicle (MPCV) spacecraft adapter. Specifically, critical design review (CDR) level analysis and flight production drawing were produced for the above mentioned hardware. In particular, the experience of this in-house design work led to increased manufacturing infrastructure for both Marshal Space Flight Center (MSFC) and Michoud Assembly Facility (MAF), improved skillsets in both analysis and design, and hands on experience in building and testing (MSA) full scale hardware. The hardware design and development processes from initiation to CDR and finally flight; resulted in many challenges and experiences that produced valuable lessons. This paper builds on these experiences of NASA in recent years on designing and fabricating flight hardware and examines the design/development processes used, as well as the challenges and lessons learned, i.e. from the initial design, loads estimation and mass constraints to structural optimization/affordability to release of production drawing to hardware manufacturing. While there are many documented design processes which a design engineer can follow, these unique experiences can offer insight into designing hardware in current program environments and present solutions to many of the challenges experienced by the engineering team.

  9. Power and Performance Trade-offs for Space Time Adaptive Processing

    SciTech Connect

    Gawande, Nitin A.; Manzano Franco, Joseph B.; Tumeo, Antonino; Tallent, Nathan R.; Kerbyson, Darren J.; Hoisie, Adolfy

    2015-07-27

    Computational efficiency – performance relative to power or energy – is one of the most important concerns when designing RADAR processing systems. This paper analyzes power and performance trade-offs for a typical Space Time Adaptive Processing (STAP) application. We study STAP implementations for CUDA and OpenMP on two computationally efficient architectures, Intel Haswell Core I7-4770TE and NVIDIA Kayla with a GK208 GPU. We analyze the power and performance of STAP’s computationally intensive kernels across the two hardware testbeds. We also show the impact and trade-offs of GPU optimization techniques. We show that data parallelism can be exploited for efficient implementation on the Haswell CPU architecture. The GPU architecture is able to process large size data sets without increase in power requirement. The use of shared memory has a significant impact on the power requirement for the GPU. A balance between the use of shared memory and main memory access leads to an improved performance in a typical STAP application.

  10. Adaptive memory: the survival scenario enhances item-specific processing relative to a moving scenario.

    PubMed

    Burns, Daniel J; Hart, Joshua; Griffith, Samantha E; Burns, Amy D

    2013-01-01

    Nairne, Thompson, and Pandeirada (2007) found that retention of words rated for their relevance to survival is superior to that of words encoded under numerous other deep processing conditions. They suggested that our memory systems might have evolved to confer an advantage for survival-relevant information. Burns, Burns, and Hwang (2011) suggested a two-process explanation of the proximate mechanisms responsible for the survival advantage. Whereas most control tasks encourage only one type of processing, the survival task encourages both item-specific and relational processing. They found that when control tasks encouraged both types of processing, the survival processing advantage was eliminated. However, none of their control conditions included non-survival scenarios (e.g., moving, vacation, etc.), so it is not clear how this two-process explanation would explain the survival advantage when scenarios are used as control conditions. The present experiments replicated the finding that the survival scenario improves recall relative to a moving scenario in both a between-lists and within-list design and also provided evidence that this difference was accompanied by an item-specific processing difference, not a difference in relational processing. The implications of these results for several existing accounts of the survival processing effect are discussed.

  11. Costal process of the first sacral vertebra: sexual dimorphism and obstetrical adaptation.

    PubMed

    Tague, Robert G

    2007-03-01

    The human sacrum is sexually dimorphic, with males being larger than females in most dimensions. Previous studies, though, suggest that females may have a longer costal process of the first sacral vertebra (S1) than males. However, these studies neither quantified nor tested statistically the costal process of S1. This study compares S1 with the five lumbar vertebrae (L1 to L5) for a number of metric dimensions, including costal process length. Four issues are addressed, the: 1) hypothesis that females have a longer costal process of S1 than males; 2)hypothesis that homologous structures (i.e., costal processes of L1 to S1) differ in their direction of sexual dimorphism; 3) importance of the costal process of S1 to the obstetrical capacity of the pelvis; and 4) evolution of sexual dimorphism in costal process length of S1. One hundred ninety-seven individuals, including males and females of American blacks and whites, from the Hamann-Todd and Terry Collections were studied. Results show that males are significantly larger than females for most vertebral measurements, except that females have a significantly longer costal process of S1 than males. Costal process length of S1 is positively correlated with the transverse diameter and circumference of the pelvic inlet. The magnitude of sexual dimorphism in costal process length of S1 ranks this measure among the most highly dimorphic of the pelvis. Compared with the humans in this study, australopithecines have a relatively long costal process of S1, but their broad sacrum was not associated with obstetrical imperatives.

  12. Including parameterization of the discrete ablation process into a planning and simulation environment for robot-assisted laser osteotomy.

    PubMed

    Burgner, Jessica; Kahrs, Lüder Alexander; Raczkowsky, Jörg; Wörn, Heinz

    2009-01-01

    Material processing using laser became a widely used method especially in the scope of industrial automation. The systems are mostly based on a precise model of the laser process and the according parameterization. Beside the industrial use the laser as an instrument to treat human tissue has become an integral part in medicine as well. Human tissue as an inhomogeneous material to process, poses the question of how to determine a model, which reflects the interaction processes with a specific laser.Recently it could be shown that the pulsed CO2 laser is suitable to ablate bony and cartilage tissue. Until now this thermo-mechanical bone ablation is not characterized as a discrete process. In order to plan and simulate the ablation process in the correct level of detail, the parameterization is indispensable. We developed a planning and simulation environment, determined parameters by confocal measurements of bony specimen and use these results to transfer planned cutting trajectories into a pulse sequence and corresponding robot locations.

  13. Waveform Design and Diversity for Advanced Space-Time Adaptive Processing and Multiple Input Multiple Output Systems

    DTIC Science & Technology

    2012-08-01

    13. SUPPLEMENTARY NOTES 14. ABSTRACT Waveform diversity refers to the adaptivity of the radar waveform to dynamically optimize the... radar performance for the particular scenario and tasks. It may also exploit adaptivity in other domains, including the antenna radiation pattern (both...Specifically, in Chapter 1, we consider the problem of waveform design for radar sensors that operate in a noncooperative network. In Chapter 2, we deal

  14. Catchment process affecting drinking water quality, including the significance of rainfall events, using factor analysis and event mean concentrations.

    PubMed

    Cinque, Kathy; Jayasuriya, Niranjali

    2010-12-01

    To ensure the protection of drinking water an understanding of the catchment processes which can affect water quality is important as it enables targeted catchment management actions to be implemented. In this study factor analysis (FA) and comparing event mean concentrations (EMCs) with baseline values were techniques used to asses the relationships between water quality parameters and linking those parameters to processes within an agricultural drinking water catchment. FA found that 55% of the variance in the water quality data could be explained by the first factor, which was dominated by parameters usually associated with erosion. Inclusion of pathogenic indicators in an additional FA showed that Enterococcus and Clostridium perfringens (C. perfringens) were also related to the erosion factor. Analysis of the EMCs found that most parameters were significantly higher during periods of rainfall runoff. This study shows that the most dominant processes in an agricultural catchment are surface runoff and erosion. It also shows that it is these processes which mobilise pathogenic indicators and are therefore most likely to influence the transport of pathogens. Catchment management efforts need to focus on reducing the effect of these processes on water quality.

  15. Adapting Rational Unified Process (RUP) approach in designing a secure e-Tendering model

    NASA Astrophysics Data System (ADS)

    Mohd, Haslina; Robie, Muhammad Afdhal Muhammad; Baharom, Fauziah; Darus, Norida Muhd; Saip, Mohamed Ali; Yasin, Azman

    2016-08-01

    e-Tendering is an electronic processing of the tender document via internet and allow tenderer to publish, communicate, access, receive and submit all tender related information and documentation via internet. This study aims to design the e-Tendering system using Rational Unified Process approach. RUP provides a disciplined approach on how to assign tasks and responsibilities within the software development process. RUP has four phases that can assist researchers to adjust the requirements of various projects with different scope, problem and the size of projects. RUP is characterized as a use case driven, architecture centered, iterative and incremental process model. However the scope of this study only focusing on Inception and Elaboration phases as step to develop the model and perform only three of nine workflows (business modeling, requirements, analysis and design). RUP has a strong focus on documents and the activities in the inception and elaboration phases mainly concern the creation of diagrams and writing of textual descriptions. The UML notation and the software program, Star UML are used to support the design of e-Tendering. The e-Tendering design based on the RUP approach can contribute to e-Tendering developers and researchers in e-Tendering domain. In addition, this study also shows that the RUP is one of the best system development methodology that can be used as one of the research methodology in Software Engineering domain related to secured design of any observed application. This methodology has been tested in various studies in certain domains, such as in Simulation-based Decision Support, Security Requirement Engineering, Business Modeling and Secure System Requirement, and so forth. As a conclusion, these studies showed that the RUP one of a good research methodology that can be adapted in any Software Engineering (SE) research domain that required a few artifacts to be generated such as use case modeling, misuse case modeling, activity

  16. Motor learning and cross-limb transfer rely upon distinct neural adaptation processes.

    PubMed

    Stöckel, Tino; Carroll, Timothy J; Summers, Jeffery J; Hinder, Mark R

    2016-08-01

    Performance benefits conferred in the untrained limb after unilateral motor practice are termed cross-limb transfer. Although the effect is robust, the neural mechanisms remain incompletely understood. In this study we used noninvasive brain stimulation to reveal that the neural adaptations that mediate motor learning in the trained limb are distinct from those that underlie cross-limb transfer to the opposite limb. Thirty-six participants practiced a ballistic motor task with their right index finger (150 trials), followed by intermittent theta-burst stimulation (iTBS) applied to the trained (contralateral) primary motor cortex (cM1 group), the untrained (ipsilateral) M1 (iM1 group), or the vertex (sham group). After stimulation, another 150 training trials were undertaken. Motor performance and corticospinal excitability were assessed before motor training, pre- and post-iTBS, and after the second training bout. For all groups, training significantly increased performance and excitability of the trained hand, and performance, but not excitability, of the untrained hand, indicating transfer at the level of task performance. The typical facilitatory effect of iTBS on MEPs was reversed for cM1, suggesting homeostatic metaplasticity, and prior performance gains in the trained hand were degraded, suggesting that iTBS interfered with learning. In stark contrast, iM1 iTBS facilitated both performance and excitability for the untrained hand. Importantly, the effects of cM1 and iM1 iTBS on behavior were exclusive to the hand contralateral to stimulation, suggesting that adaptations within the untrained M1 contribute to cross-limb transfer. However, the neural processes that mediate learning in the trained hemisphere vs. transfer in the untrained hemisphere appear distinct.

  17. Multi-modal iterative adaptive processing (MIAP) performance in the discrimination mode for landmine detection

    NASA Astrophysics Data System (ADS)

    Yu, Yongli; Collins, Leslie M.

    2005-06-01

    Due to the nature of landmine detection, a high detection probability (Pd) is required to avoid casualties and injuries. However, high Pd is often obtained at the price of extremely high false alarm rates. It is widely accepted that no single sensor technology has the ability to achieve the required detection rate while keeping acceptably low false alarm rates for all types of mines in all types of soil and with all types of false targets. Remarkable advances in sensor technology for landmine detection have made multi-sensor fusion an attractive alternative to single sensor detection techniques. Hence, multi-sensor fusion mine detection systems, which use complementary sensor technologies, are proposed. Previously we proposed a new multi-sensor fusion algorithm called Multi-modal Iterative Adaptive Processing (MIAP), which incorporates information from multiple sensors in an adaptive Bayesian decision framework and the identification capabilities of multiple sensors are utilized to modify the statistical models utilized by the mine detector. Simulation results demonstrate the improvement in performance obtained using the MIAP algorithm. In this paper, we assume a hand-held mine detection system utilizing both an electromagnetic induction sensor (EMI) and a ground-penetrating radar (GPR). The hand-held mine detection sensors are designed to have two modes of operations: search mode and discrimination mode. Search mode generates an initial causal detection on the suspected location; and discrimination mode confirms whether there is a mine. The MIAP algorithm is applied in the discrimination mode for hand-held mine detection. The performance of the detector is evaluated on a data set collected by the government, and the performance is compared with the other traditional fusion results.

  18. Calibration of ultra high speed laser engraving processes by correlating influencing variables including correlative evaluation with SEM and CLSM

    NASA Astrophysics Data System (ADS)

    Bohrer, Markus; Vaupel, Matthias; Nirnberger, Robert; Weinberger, Bernhard

    2016-03-01

    Laser engraving is used for decades as a well-established process e. g. for the production of print and embossing forms for many goods in daily life, e. g. decorated cans and printed bank notes. Up to now it is more or less a so-called fire-and-forget process. From the original artist's plan to the digitization, then from the laser source itself (with electronic signals, RF and plasma discharge regarding CO2 lasers) to the behavior of the optical beam delivery — especially if an AOM is used — to the interaction of the laser beam with the material itself is a long process chain. The most recent results using CO2 lasers with AOMs and the research done with scanning electron microscope (SEM) and confocal laser scanning microscope (CLSM) — as a set for correlative microscopy to evaluate the high speed engraving characteristics — are presented in this paper.

  19. Adaptive sparse signal processing of on-orbit lightning data using learned dictionaries

    NASA Astrophysics Data System (ADS)

    Moody, Daniela I.; Smith, David A.; Hamlin, Timothy D.; Light, Tess E.; Suszcynsky, David M.

    2013-05-01

    For the past two decades, there has been an ongoing research effort at Los Alamos National Laboratory to learn more about the Earth's radiofrequency (RF) background utilizing satellite-based RF observations of terrestrial lightning. The Fast On-orbit Recording of Transient Events (FORTE) satellite provided a rich RF lighting database, comprising of five years of data recorded from its two RF payloads. While some classification work has been done previously on the FORTE RF database, application of modern pattern recognition techniques may advance lightning research in the scientific community and potentially improve on-orbit processing and event discrimination capabilities for future satellite payloads. We now develop and implement new event classification capability on the FORTE database using state-of-the-art adaptive signal processing combined with compressive sensing and machine learning techniques. The focus of our work is improved feature extraction using sparse representations in learned dictionaries. Conventional localized data representations for RF transients using analytical dictionaries, such as a short-time Fourier basis or wavelets, can be suitable for analyzing some types of signals, but not others. Instead, we learn RF dictionaries directly from data, without relying on analytical constraints or additional knowledge about the signal characteristics, using several established machine learning algorithms. Sparse classification features are extracted via matching pursuit search over the learned dictionaries, and used in conjunction with a statistical classifier to distinguish between lightning types. We present preliminary results of our work and discuss classification scenarios and future development.

  20. Adaptive Signal Processing Testbed: VME-based DSP board market survey

    NASA Astrophysics Data System (ADS)

    Ingram, Rick E.

    1992-04-01

    The Adaptive Signal Processing Testbed (ASPT) is a real-time multiprocessor system utilizing digital signal processor technology on VMEbus based printed circuit boards installed on a Sun workstation. The ASPT has specific requirements, particularly as regards to the signal excision application, with respect to interfacing with current and planned data generation equipment, processing of the data, storage to disk of final and intermediate results, and the development tools for applications development and integration into the overall EW/COM computing environment. A prototype ASPT was implemented using three VME-C-30 boards from Applied Silicon. Experience gained during the prototype development led to the conclusions that interprocessor communications capability is the most significant contributor to overall ASPT performance. In addition, the host involvement should be minimized. Boards using different processors were evaluated with respect to the ASPT system requirements, pricing, and availability. Specific recommendations based on various priorities are made as well as recommendations concerning the integration and interaction of various tools developed during the prototype implementation.

  1. An adaptive ultrasonic backscattered signal processing technique for instantaneous characteristic frequency detection.

    PubMed

    Jin, Bo; Vai, Mang I

    2014-01-01

    Ultrasonic diagnosis that is convenient and nondestructive to the human body is widely used in medicine. In clinical, ultrasonic backscattered signals characteristics are utilized to acquire information of the human body tissues to perform diagnosis. In this paper, an adaptive ultrasonic backscattered signal processing technique for instantaneous characteristic frequency detection based on the marginal spectrum is presented. In the beginning, the ultrasonic backscattered signal is decomposed into a series of intrinsic mode functions (IMFs) by the Ensemble Empirical Mode Decomposition (EEMD) algorithm. Then the Hilbert spectrum is gained by the Hilbert transform on the IMFs decomposed and screened. Finally, the time-frequency information in the Hilbert spectrum is utilized to extract the instantaneous characteristic frequency based on the marginal spectrum features to detect the objective. With this technique, the spacing between tissues can be estimated for tissue characterization by processing multiple echoes even in the complicated environment. In the simulation study, comparing with the FFT, the technique presented shows its strong noise immunity and indicates its validity in instantaneous characteristic frequency detection.

  2. Multispectral image sharpening using a shift-invariant wavelet transform and adaptive processing of multiresolution edges

    USGS Publications Warehouse

    Lemeshewsky, G.P.; Rahman, Z.-U.; Schowengerdt, R.A.; Reichenbach, S.E.

    2002-01-01

    Enhanced false color images from mid-IR, near-IR (NIR), and visible bands of the Landsat thematic mapper (TM) are commonly used for visually interpreting land cover type. Described here is a technique for sharpening or fusion of NIR with higher resolution panchromatic (Pan) that uses a shift-invariant implementation of the discrete wavelet transform (SIDWT) and a reported pixel-based selection rule to combine coefficients. There can be contrast reversals (e.g., at soil-vegetation boundaries between NIR and visible band images) and consequently degraded sharpening and edge artifacts. To improve performance for these conditions, I used a local area-based correlation technique originally reported for comparing image-pyramid-derived edges for the adaptive processing of wavelet-derived edge data. Also, using the redundant data of the SIDWT improves edge data generation. There is additional improvement because sharpened subband imagery is used with the edge-correlation process. A reported technique for sharpening three-band spectral imagery used forward and inverse intensity, hue, and saturation transforms and wavelet-based sharpening of intensity. This technique had limitations with opposite contrast data, and in this study sharpening was applied to single-band multispectral-Pan image pairs. Sharpening used simulated 30-m NIR imagery produced by degrading the spatial resolution of a higher resolution reference. Performance, evaluated by comparison between sharpened and reference image, was improved when sharpened subband data were used with the edge correlation.

  3. Innovative techniques for the production of energetic radicals for lunar materials processing including photogeneration via concentrated solar energy

    NASA Technical Reports Server (NTRS)

    Osborn, D. E.; Lynch, D. C.; Fozzolari, R.

    1991-01-01

    A technique for photo generation of radicals is discussed that can be used in the recovery of oxygen and metals from extraterrestrial resources. The concept behind this work was to examine methods whereby radicals can be generated and used in the processing of refractory materials. In that regard, the focus is on the use of sunlight. Sunlight provides useful energy for processing in the forms of both thermal and quantum energy. A number of experiments were conducted in the chlorination of metals with and without the aid of UV and near UV light. The results of some of those experiments are discussed.

  4. Adaptation of CHO cells in serum-free conditions for erythropoietin production: Application of EVOP technique for process optimization.

    PubMed

    Jukić, Suzana; Bubenik, Dijana; Pavlović, Nediljko; Tušek, Ana Jurinjak; Srček, Višnja Gaurina

    2016-09-01

    Mammalian cell cultures are the preferred expression systems for the production of biopharmaceuticals requiring posttranslational processing. Usually, cell cultures are cultivated in medium supplemented with serum, which supports cell proliferation, viability, and productivity. However, due to scientific and regulatory concerns, serum-free conditions are required in recombinant protein production. Cell lines that are intended for commercial recombinant protein production have to adapt to serum- or protein-free conditions early in their development. This is a labor- and time-consuming process because of the specific cell requirements related to their adaptation in new microenvironment. In the present study, a Chinese hamster ovary (CHO) cell line producing glycosylated recombinant human erythropoietin (rhEPO) was adapted for growth and rhEPO production in serum- and protein-free conditions. The physiology, growth parameters, and morphology of the CHO cells and rhEPO biosynthesis and structure were closely monitored during the adaptation process to avoid unwanted selection of cell subpopulations. The results showed that the CHO cells were successfully adapted to suspension growth and rhEPO production in the protein-free conditions and that the structure of rhEPO remained nearly unchanged. In addition, during rhEPO production in the protein-free suspension conditions, the agitation rate seem to be significant for optimal process performance in contrast to the initial cell concentration, evaluated through evolutionary operation method.

  5. Outcome after relapse of acute lymphoblastic leukemia in adult patients included in four consecutive risk-adapted trials by the PETHEMA Study Group

    PubMed Central

    Oriol, Albert; Vives, Susana; Hernández-Rivas, Jesús-María; Tormo, Mar; Heras, Inmaculada; Rivas, Concepción; Bethencourt, Concepción; Moscardó, Federico; Bueno, Javier; Grande, Carlos; del Potro, Eloy; Guardia, Ramon; Brunet, Salut; Bergua, Juan; Bernal, Teresa; Moreno, Maria-José; Calvo, Carlota; Bastida, Pilar; Feliu, Evarist; Ribera, Josep-Maria

    2010-01-01

    Background About one half of adults with acute lymphoblastic leukemia are not cured of the disease and ultimately die. The objective of this study was to explore the factors influencing the outcome of adult patients with relapsed acute lymphoblastic leukemia. Design and Methods We analyzed the characteristics, the outcome and the prognostic factors for survival after first relapse in a series of 263 adult patients with acute lymphoblastic leukemia (excluding those with mature B-cell acute lymphoblastic leukemia) prospectively enrolled in four consecutive risk-adapted PETHEMA trials. Results The median overall survival after relapse was 4.5 months (95% CI, 4–5 months) with a 5-year overall survival of 10% (95% CI, 8%–12%); 45% of patients receiving intensive second-line treatment achieved a second complete remission and 22% (95% CI, 14%–30%) of them remained disease free at 5 years. Factors predicting a good outcome after rescue therapy were age less than 30 years (2-year overall survival of 21% versus 10% for those over 30 years old; P<0.022) and a first remission lasting more than 2 years (2-year overall survival of 36% versus 17% among those with a shorter first remission; P<0.001). Patients under 30 years old whose first complete remission lasted longer than 2 years had a 5-year overall survival of 38% (95% CI, 23%–53%) and a 5-year disease-free survival of 53% (95% CI, 34%–72%). Conclusions The prognosis of adult patients with acute lymphoblastic leukemia who relapse is poor. Those aged less than 30 years with a first complete remission lasting longer than 2 years have reasonable possibilities of becoming long-term survivors while patients over this age or those who relapse early cannot be successfully rescued using the therapies currently available. PMID:20145276

  6. Conversion of Extracted Oil Cake Fibers into Bioethanol Including DDGS, Canola, Sunflower, Seasame, Soy, and Peanut for Integrated Biodiesel Processing

    Technology Transfer Automated Retrieval System (TEKTRAN)

    We have come up with a novel integrated approach where biodiesel processing can be potentially done in-house by producing ethanol from edible oilseeds after hexane extraction to remove residual oil. In addition, we have demonstrated how ethanol could be manufactured from widely available oil cakes ...

  7. Learning Process and Learning Outcomes of Video Podcasts Including the Instructor and PPT Slides: A Chinese Case

    ERIC Educational Resources Information Center

    Pi, Zhongling; Hong, Jianzhong

    2016-01-01

    Video podcasts have become one of the fastest developing trends in learning and teaching. The study explored the effect of the presenting mode of educational video podcasts on the learning process and learning outcomes. Prior to viewing a video podcast, the 94 Chinese undergraduates participating in the study completed a demographic questionnaire…

  8. Building a Steganography Program Including How to Load, Process, and Save JPEG and PNG Files in Java

    ERIC Educational Resources Information Center

    Courtney, Mary F.; Stix, Allen

    2006-01-01

    Instructors teaching beginning programming classes are often interested in exercises that involve processing photographs (i.e., files stored as .jpeg). They may wish to offer activities such as color inversion, the color manipulation effects archived with pixel thresholding, or steganography, all of which Stevenson et al. [4] assert are sought by…

  9. Rational adaptation under task and processing constraints: implications for testing theories of cognition and action.

    PubMed

    Howes, Andrew; Lewis, Richard L; Vera, Alonso

    2009-10-01

    The authors assume that individuals adapt rationally to a utility function given constraints imposed by their cognitive architecture and the local task environment. This assumption underlies a new approach to modeling and understanding cognition-cognitively bounded rational analysis-that sharpens the predictive acuity of general, integrated theories of cognition and action. Such theories provide the necessary computational means to explain the flexible nature of human behavior but in doing so introduce extreme degrees of freedom in accounting for data. The new approach narrows the space of predicted behaviors through analysis of the payoff achieved by alternative strategies, rather than through fitting strategies and theoretical parameters to data. It extends and complements established approaches, including computational cognitive architectures, rational analysis, optimal motor control, bounded rationality, and signal detection theory. The authors illustrate the approach with a reanalysis of an existing account of psychological refractory period (PRP) dual-task performance and the development and analysis of a new theory of ordered dual-task responses. These analyses yield several novel results, including a new understanding of the role of strategic variation in existing accounts of PRP and the first predictive, quantitative account showing how the details of ordered dual-task phenomena emerge from the rational control of a cognitive system subject to the combined constraints of internal variance, motor interference, and a response selection bottleneck.

  10. An adaptive line enhancement method for UWB proximity fuze signal processing based on correlation matrix estimation with time delay factor

    NASA Astrophysics Data System (ADS)

    Li, Meng; Huang, Zhonghua

    2016-10-01

    Signal processing for an ultra-wideband radio fuze receiver involves some challenges: it requires high real-time performance; the output signal is mixed with broadband noise; and the signal-to-noise ratio (SNR) decreases with increased detection range. The adaptive line enhancement method is used to filter the output signal of the ultra-wideband radio fuze receiver, and thus suppress the wideband noise from the output signal of the receiver and extract the target characteristic signal. The filter input correlation matrix estimation algorithm is based on the delay factor of an adaptive line enhancer. The proposed adaptive algorithm was used to filter and reduce noise in the output signal from the fuze receiver. Simulation results showed that the SNR of the output signal after adaptive noise reduction was improved by 20 dB, which was higher than the SNR of the output signal after finite impulse response (FIR) filtering of around 10 dB.

  11. 77 FR 41807 - New Gear Process, a Division of Magna Powertrain, Including On-Site Leased Workers From ABM...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-16

    ... Leased Workers From ABM Janitorial Service Northeast, Inc., East Syracuse, NY; Amended Certification... company reports that workers leased from ABM Janitorial Service Northeast, Inc. were employed on-site at... these findings, the Department is amending this certification to include workers leased from...

  12. Innovative techniques for the production of energetic radicals for lunar materials processing including photogeneration via concentrated solar energy

    NASA Technical Reports Server (NTRS)

    Osborn, D. E.; Lynch, D. C.; Fazzolari, R.

    1990-01-01

    The Department of Materials Science and Engineering (MSE) is investigating the use of monatomic chlorine produced in a cold plasma to recover oxygen and metallurgically significant metals from lunar materials. Development of techniques for the production of the chlorine radical (and other energetic radicals for these processes) using local planetary resources is a key step for a successful approach. It was demonstrated terrestrially that the use of UV light to energize the photogeneration of OH radicals from ozone or hydrogen peroxide in aqueous solutions can lead to rapid reaction rates for the breakdown of toxic organic compounds in water. A key question is how to use the expanded solar resource at the lunar surface to generate process-useful radicals. This project is aimed at investigating that question.

  13. 41 CFR 102-33.90 - What is the process for budgeting to acquire a Federal aircraft (including a Federal aircraft...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... budgeting to acquire a Federal aircraft (including a Federal aircraft transferred from another executive... AIRCRAFT Acquiring Government Aircraft and Aircraft Parts The Process for Budgeting to Acquire Government Aircraft § 102-33.90 What is the process for budgeting to acquire a Federal aircraft (including a...

  14. 41 CFR 102-33.90 - What is the process for budgeting to acquire a Federal aircraft (including a Federal aircraft...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... budgeting to acquire a Federal aircraft (including a Federal aircraft transferred from another executive... AIRCRAFT Acquiring Government Aircraft and Aircraft Parts The Process for Budgeting to Acquire Government Aircraft § 102-33.90 What is the process for budgeting to acquire a Federal aircraft (including a...

  15. Parallel processing of Eulerian-Lagrangian, cell-based adaptive method for moving boundary problems

    NASA Astrophysics Data System (ADS)

    Kuan, Chih-Kuang

    In this study, issues and techniques related to the parallel processing of the Eulerian-Lagrangian method for multi-scale moving boundary computation are investigated. The scope of the study consists of the Eulerian approach for field equations, explicit interface-tracking, Lagrangian interface modification and reconstruction algorithms, and a cell-based unstructured adaptive mesh refinement (AMR) in a distributed-memory computation framework. We decomposed the Eulerian domain spatially along with AMR to balance the computational load of solving field equations, which is a primary cost of the entire solver. The Lagrangian domain is partitioned based on marker vicinities with respect to the Eulerian partitions to minimize inter-processor communication. Overall, the performance of an Eulerian task peaks at 10,000-20,000 cells per processor, and it is the upper bound of the performance of the Eulerian- Lagrangian method. Moreover, the load imbalance of the Lagrangian task is not as influential as the communication overhead of the Eulerian-Lagrangian tasks on the overall performance. To assess the parallel processing capabilities, a high Weber number drop collision is simulated. The high convective to viscous length scale ratios result in disparate length scale distributions; together with the moving and topologically irregular interfaces, the computational tasks require temporally and spatially resolved treatment adaptively. The techniques presented enable us to perform original studies to meet such computational requirements. Coalescence, stretch, and break-up of satellite droplets due to the interfacial instability are observed in current study, and the history of interface evolution is in good agreement with the experimental data. The competing mechanisms of the primary and secondary droplet break up, along with the gas-liquid interfacial dynamics are systematically investigated. This study shows that Rayleigh-Taylor instability on the edge of an extruding sheet

  16. Practical Adaptations of Cognitive Processing Therapy with Bosnian Refugees: Implications for Adapting Practice to a Multicultural Clientele

    ERIC Educational Resources Information Center

    Schulz, Priscilla M.; Huber, L. Christian; Resick, Patricia A.

    2006-01-01

    Recent findings suggest that established psychological treatments for PTSD are effective for diverse populations, including war refugees who have experienced multiple and severe losses, deprivations, hardships, and atrocities. Treating non-English-speaking traumatized refugees requires the clinician to overcome linguistic and various cultural…

  17. WISC-IV profile in high-functioning autism spectrum disorders: impaired processing speed is associated with increased autism communication symptoms and decreased adaptive communication abilities.

    PubMed

    Oliveras-Rentas, Rafael E; Kenworthy, Lauren; Roberson, Richard B; Martin, Alex; Wallace, Gregory L

    2012-05-01

    Changes in the Wechsler Intelligence Scales for Children-IV (WISC-IV) may affect the IQ profile characteristic of autism spectrum disorders (ASD). Moreover, the association of particular component cognitive abilities (unlike overall IQ) with symptomatology and adaptive functioning in ASD remains unclear. This archival study characterizes the WISC-IV IQ profile among 56 high-functioning (IQ > 70) children with ASD and correlates WISC-IV performance with ASD and ADHD symptomatology and adaptive functioning. The ASD WISC-IV profile included strengths on Matrix Reasoning and Similarities, weaknesses on Comprehension (which correlated negatively with social symptoms) and the subtests comprising the Processing Speed Index (Coding, Symbol Search). Processing speed task performance correlated negatively with communication symptoms and positively with communication abilities, indicating its importance to functional outcomes in ASD.

  18. WISC-IV Profile in High-Functioning Autism Spectrum Disorders: Impaired Processing Speed is Associated with Increased Autism Communication Symptoms and Decreased Adaptive Communication Abilities

    PubMed Central

    Oliveras-Rentas, Rafael E.; Kenworthy, Lauren; Roberson, Richard B.; Martin, Alex; Wallace, Gregory L.

    2012-01-01

    Changes in the Wechsler Intelligence Scales for Children-IV (WISC-IV) may affect the IQ profile characteristic of autism spectrum disorders (ASD). Moreover, the association of particular component cognitive abilities (unlike overall IQ) with symptomatology and adaptive functioning in ASD remains unclear. This archival study characterizes the WISC-IV IQ profile among 51 high-functioning (IQ>70) children with ASD and correlates WISC-IV performance with ASD and ADHD symptomatology and adaptive functioning. The ASD WISC-IV profile included strengths on Matrix Reasoning and Similarities, weaknesses on Comprehension (which correlated negatively with social symptoms) and the subtests comprising the Processing Speed Index (Coding, Symbol Search). Processing speed task performance correlated negatively with communication symptoms and positively with communication abilities, indicating its importance to functional outcomes in ASD. PMID:21638108

  19. Advanced Manufacturing Process for Lower Cost Rechargeable Lithium-ion Batteries for DOD Including the BB2590

    DTIC Science & Technology

    2013-11-30

    Nickelate in 18650 Cell 24 8. Installation of Resistance Welder 25 9. Bi-Cell Vacuum Dryer and with Activation Box 26 10. Semi...DOD lithium-ion rechargeable cells/batteries are composed of combinations using Asian 18650 cells including the BB2590. This dependence is due to the...much lower cost of the Asian and particularly the Chinese 18650 cells which are made on very large scale and also with lower labor costs. LithChem

  20. Adapting the SpaceCube v2.0 Data Processing System for Mission-Unique Application Requirements

    NASA Technical Reports Server (NTRS)

    Petrick, David

    2015-01-01

    The SpaceCubeTM v2.0 system is a superior high performance, reconfigurable, hybrid data processing system that can be used in a multitude of applications including those that require a radiation hardened and reliable solution. This paper provides an overview of the design architecture, flexibility, and the advantages of the modular SpaceCube v2.0 high performance data processing system for space applications. The current state of the proven SpaceCube technology is based on nine years of engineering and operations. Five systems have been successfully operated in space starting in 2008 with four more to be delivered for launch vehicle integration in 2015. The SpaceCube v2.0 system is also baselined as the avionics solution for five additional flight projects and is always a top consideration as the core avionics for new instruments or spacecraft control. This paper will highlight how this multipurpose system is currently being used to solve design challenges of three independent applications. The SpaceCube hardware adapts to new system requirements by allowing for application-unique interface cards that are utilized by reconfiguring the underlying programmable elements on the core processor card. We will show how this system is being used to improve on a heritage NASA GPS technology, enable a cutting-edge LiDAR instrument, and serve as a typical command and data handling (CDH) computer for a space robotics technology demonstration.

  1. Adapting the SpaceCube v2.0 Data Processing System for Mission-Unique Application Requirements

    NASA Technical Reports Server (NTRS)

    Petrick, David; Gill, Nat; Hasouneh, Munther; Stone, Robert; Winternitz, Luke; Thomas, Luke; Davis, Milton; Sparacino, Pietro; Flatley, Thomas

    2015-01-01

    The SpaceCube (sup TM) v2.0 system is a superior high performance, reconfigurable, hybrid data processing system that can be used in a multitude of applications including those that require a radiation hardened and reliable solution. This paper provides an overview of the design architecture, flexibility, and the advantages of the modular SpaceCube v2.0 high performance data processing system for space applications. The current state of the proven SpaceCube technology is based on nine years of engineering and operations. Five systems have been successfully operated in space starting in 2008 with four more to be delivered for launch vehicle integration in 2015. The SpaceCube v2.0 system is also baselined as the avionics solution for five additional flight projects and is always a top consideration as the core avionics for new instruments or spacecraft control. This paper will highlight how this multipurpose system is currently being used to solve design challenges of three independent applications. The SpaceCube hardware adapts to new system requirements by allowing for application-unique interface cards that are utilized by reconfiguring the underlying programmable elements on the core processor card. We will show how this system is being used to improve on a heritage NASA GPS technology, enable a cutting-edge LiDAR instrument, and serve as a typical command and data handling (C&DH) computer for a space robotics technology demonstration.

  2. Segment Tracking via a Spatiotemporal Linking Process including Feedback Stabilization in an n-D Lattice Model

    PubMed Central

    Dellen, Babette; Aksoy, Eren Erdal; Wörgötter, Florentin

    2009-01-01

    Model-free tracking is important for solving tasks such as moving-object tracking and action recognition in cases where no prior object knowledge is available. For this purpose, we extend the concept of spatially synchronous dynamics in spin-lattice models to the spatiotemporal domain to track segments within an image sequence. The method is related to synchronization processes in neural networks and based on superparamagnetic clustering of data. Spin interactions result in the formation of clusters of correlated spins, providing an automatic labeling of corresponding image regions. The algorithm obeys detailed balance. This is an important property as it allows for consistent spin-transfer across subsequent frames, which can be used for segment tracking. Therefore, in the tracking process the correct equilibrium will always be found, which is an important advance as compared with other more heuristic tracking procedures. In the case of long image sequences, i.e., movies, the algorithm is augmented with a feedback mechanism, further stabilizing segment tracking. PMID:22291568

  3. Model and Processes of Acceptance and Commitment Therapy (ACT) for Chronic Pain Including a Closer Look at the Self.

    PubMed

    Yu, Lin; McCracken, Lance M

    2016-02-01

    Acceptance and commitment therapy (ACT) is one of the so called "third-wave" cognitive behavioral therapies. It has been increasingly applied to chronic pain, and there is accumulating evidence to support its effectiveness. ACT is based on a model of general human functioning called the psychological flexibility (PF) model. Most facets of the PF model have been examined in chronic pain. However, a potential key facet related to "self" appears underappreciated. Indeed, a positive or healthy sense of self seems essential to our well-being, and there have been numerous studies of the self in chronic pain. At the same time, these studies are not currently well organized or easy to summarize. This lack of clarity and integration creates barriers to progress in this area of research. PF with its explicit inclusion of self-related therapeutic processes within a broad, integrative, theoretical model may help. The current review summarizes the PF model in the context of chronic pain with a specific emphasis on the parts of the model that address self-related processes.

  4. Efficient Time-Domain Imaging Processing for One-Stationary Bistatic Forward-Looking SAR Including Motion Errors.

    PubMed

    Xie, Hongtu; Shi, Shaoying; Xiao, Hui; Xie, Chao; Wang, Feng; Fang, Qunle

    2016-11-12

    With the rapid development of the one-stationary bistatic forward-looking synthetic aperture radar (OS-BFSAR) technology, the huge amount of the remote sensing data presents challenges for real-time imaging processing. In this paper, an efficient time-domain algorithm (ETDA) considering the motion errors for the OS-BFSAR imaging processing, is presented. This method can not only precisely handle the large spatial variances, serious range-azimuth coupling and motion errors, but can also greatly improve the imaging efficiency compared with the direct time-domain algorithm (DTDA). Besides, it represents the subimages on polar grids in the ground plane instead of the slant-range plane, and derives the sampling requirements considering motion errors for the polar grids to offer a near-optimum tradeoff between the imaging precision and efficiency. First, OS-BFSAR imaging geometry is built, and the DTDA for the OS-BFSAR imaging is provided. Second, the polar grids of subimages are defined, and the subaperture imaging in the ETDA is derived. The sampling requirements for polar grids are derived from the point of view of the bandwidth. Finally, the implementation and computational load of the proposed ETDA are analyzed. Experimental results based on simulated and measured data validate that the proposed ETDA outperforms the DTDA in terms of the efficiency improvement.

  5. Efficient Time-Domain Imaging Processing for One-Stationary Bistatic Forward-Looking SAR Including Motion Errors

    PubMed Central

    Xie, Hongtu; Shi, Shaoying; Xiao, Hui; Xie, Chao; Wang, Feng; Fang, Qunle

    2016-01-01

    With the rapid development of the one-stationary bistatic forward-looking synthetic aperture radar (OS-BFSAR) technology, the huge amount of the remote sensing data presents challenges for real-time imaging processing. In this paper, an efficient time-domain algorithm (ETDA) considering the motion errors for the OS-BFSAR imaging processing, is presented. This method can not only precisely handle the large spatial variances, serious range-azimuth coupling and motion errors, but can also greatly improve the imaging efficiency compared with the direct time-domain algorithm (DTDA). Besides, it represents the subimages on polar grids in the ground plane instead of the slant-range plane, and derives the sampling requirements considering motion errors for the polar grids to offer a near-optimum tradeoff between the imaging precision and efficiency. First, OS-BFSAR imaging geometry is built, and the DTDA for the OS-BFSAR imaging is provided. Second, the polar grids of subimages are defined, and the subaperture imaging in the ETDA is derived. The sampling requirements for polar grids are derived from the point of view of the bandwidth. Finally, the implementation and computational load of the proposed ETDA are analyzed. Experimental results based on simulated and measured data validate that the proposed ETDA outperforms the DTDA in terms of the efficiency improvement. PMID:27845757

  6. Sparsity-Based Space-Time Adaptive Processing Using OFDM Radar

    SciTech Connect

    Sen, Satyabrata

    2012-01-01

    We propose a sparsity-based space-time adaptive processing (STAP) algorithm to detect a slowly-moving target using an orthogonal frequency division multiplexing (OFDM) radar. We observe that the target and interference spectra are inherently sparse in the spatio-temporal domain, and hence we exploit that sparsity to develop an efficient STAP technique. In addition, the use of an OFDM signal increases the frequency diversity of our system, as different scattering centers of a target resonate at different frequencies, and thus improves the target detectability. First, we formulate a realistic sparse-measurement model for an OFDM radar considering both the clutter and jammer as the interfering sources. Then, we show that the optimal STAP-filter weight-vector is equal to the generalized eigenvector corresponding to the minimum generalized eigenvalue of the interference and target covariance matrices. To estimate the target and interference covariance matrices, we apply a residual sparse-recovery technique that enables us to incorporate the partially known support of the sparse vector. Our numerical results demonstrate that the sparsity-based STAP algorithm, with considerably lesser number of secondary data, produces an equivalent performance as the other existing STAP techniques.

  7. Use of adaptive hybrid filtering process in Crohn's disease lesion detection from real capsule endoscopy videos.

    PubMed

    Charisis, Vasileios S; Hadjileontiadis, Leontios J

    2016-03-01

    The aim of this Letter is to present a new capsule endoscopy (CE) image analysis scheme for the detection of small bowel ulcers that relate to Crohn's disease. More specifically, this scheme is based on: (i) a hybrid adaptive filtering (HAF) process, that utilises genetic algorithms to the curvelet-based representation of images for efficient extraction of the lesion-related morphological characteristics, (ii) differential lacunarity (DL) analysis for texture feature extraction from the HAF-filtered images and (iii) support vector machines for robust classification performance. For the training of the proposed scheme, namely HAF-DL, an 800-image database was used and the evaluation was based on ten 30-second long endoscopic videos. Experimental results, along with comparison with other related efforts, have shown that the HAF-DL approach evidently outperforms the latter in the field of CE image analysis for automated lesion detection, providing higher classification results. The promising performance of HAF-DL paves the way for a complete computer-aided diagnosis system that could support the physicians' clinical practice.

  8. Reduced-dimension space-time adaptive processing based on angle-Doppler correlation coefficient

    NASA Astrophysics Data System (ADS)

    Li, Ruiyang; Li, Jun; Zhang, Wei; He, Zishu

    2016-12-01

    Traditional space-time adaptive processing (STAP) is a strategy for clutter suppression in airborne radar, which requires a large number of computational complexity and secondary data. In order to address the problem, reduced-dimension (RD) STAP is generally used. We propose a novel RD STAP through searching the best channels as the auxiliary channels to cancel the interference. Based on the estimation of the clutter Fourier basis vectors offline, a parameter named angle-Doppler correlation coefficient (AD C 2) is constructed to evaluate the capability of each auxiliary channel in clutter suppression, and the best sets of RD channels can be selected. The proposed algorithm can achieve the best detection performance with the fixed number of auxiliary channel. When the degrees of freedom (DOF) are restricted to a small value, only one auxiliary channel is needed to guarantee the SINR loss less than 3 dB. Therefore, the requirement of the training sample can be reduced, which makes the proposed approach more suitable for the heterogeneous clutter environments.

  9. Learning from experience: Event-related potential correlates of reward processing, neural adaptation, and behavioral choice

    PubMed Central

    Walsh, Matthew M.; Anderson, John R.

    2012-01-01

    To behave adaptively, we must learn from the consequences of our actions. Studies using event-related potentials (ERPs) have been informative with respect to the question of how such learning occurs. These studies have revealed a frontocentral negativity termed the feedback-related negativity (FRN) that appears after negative feedback. According to one prominent theory, the FRN tracks the difference between the values of actual and expected outcomes, or reward prediction errors. As such, the FRN provides a tool for studying reward valuation and decision making. We begin this review by examining the neural significance of the FRN. We then examine its functional significance. To understand the cognitive processes that occur when the FRN is generated, we explore variables that influence its appearance and amplitude. Specifically, we evaluate four hypotheses: (1) the FRN encodes a quantitative reward prediction error; (2) the FRN is evoked by outcomes and by stimuli that predict outcomes; (3) the FRN and behavior change with experience; and (4) the system that produces the FRN is maximally engaged by volitional actions. PMID:22683741

  10. Separate channels for processing form, texture, and color: evidence from FMRI adaptation and visual object agnosia.

    PubMed

    Cavina-Pratesi, C; Kentridge, R W; Heywood, C A; Milner, A D

    2010-10-01

    Previous neuroimaging research suggests that although object shape is analyzed in the lateral occipital cortex, surface properties of objects, such as color and texture, are dealt with in more medial areas, close to the collateral sulcus (CoS). The present study sought to determine whether there is a single medial region concerned with surface properties in general or whether instead there are multiple foci independently extracting different surface properties. We used stimuli varying in their shape, texture, or color, and tested healthy participants and 2 object-agnosic patients, in both a discrimination task and a functional MR adaptation paradigm. We found a double dissociation between medial and lateral occipitotemporal cortices in processing surface (texture or color) versus geometric (shape) properties, respectively. In Experiment 2, we found that the medial occipitotemporal cortex houses separate foci for color (within anterior CoS and lingual gyrus) and texture (caudally within posterior CoS). In addition, we found that areas selective for shape, texture, and color individually were quite distinct from those that respond to all of these features together (shape and texture and color). These latter areas appear to correspond to those associated with the perception of complex stimuli such as faces and places.

  11. Is the rapid adaptation paradigm too rapid? Implications for face and object processing.

    PubMed

    Nemrodov, Dan; Itier, Roxane J

    2012-07-16

    Rapid adaptation is an adaptation procedure in which adaptors and test stimuli are presented in rapid succession. The current study tested the validity of this method for early ERP components by investigating the specificity of the adaptation effect on the face-sensitive N170 ERP component across multiple test stimuli. Experiments 1 and 2 showed identical response patterns for house and upright face test stimuli using the same adaptor stimuli. The results were also identical to those reported in a previous study using inverted face test stimuli (Nemrodov and Itier, 2011). In Experiment 3 all possible adaptor-test combinations between upright face, house, chair and car stimuli were used and no interaction between adaptor and test category, expected in the case of test-specific adaptation, was found. These results demonstrate that the rapid adaptation paradigm does not produce category-specific adaptation effects around 170-200 ms following test stimulus onset, a necessary condition for the interpretation of adaptation results. These results suggest the rapid categorical adaptation paradigm does not work.

  12. Development and verification of long-range atmospheric transport model of radon-222 and lead-210 including scavenging process

    SciTech Connect

    Hirao, Shigekazu; Nono, Yuki; Yamazawa, Hiromi; Moriizumi, Jun; Iida, Takao; Yoshioka, Katsuhiro

    2008-08-07

    A three-dimensional Eulerian atmospheric long-range transport model of radon-222 ({sup 222}Rn) and lead-210 ({sup 210}Pb) coupled with meteorological model MM5 was developed. The model calculates advection, diffusion, radiation decay and deposition processes in a horizontal scale of several thousand kilometers. This model was applied to East Asia. Performance of the model was evaluated with measured hourly surface air {sup 222}Rn concentration and monthly {sup 210}Pb deposition. The model verification was done with respect to the following points: 1) the sensitivity of vertical distribution of turbulent diffusivity and 2) the accuracy of spatial distribution of precipitation. In this report, improvement of the model performance is also discussed.

  13. Incorporating Deeply Uncertain Factors into the Many Objective Search Process: Improving Adaptation to Environmental Change

    NASA Astrophysics Data System (ADS)

    Kasprzyk, J. R.; Watson, A. A.

    2014-12-01

    Deep uncertainty refers to situations in which decision makers or stakeholders do not know, or cannot fully agree upon, the full suite of risk factors within a planning problem. This phenomenon is especially important when considering scenarios of future environmental change, since there exist multiple trajectories of environmental forcings (e.g., streamflow timing and magnitude) and socioeconomic factors (e.g., population growth). This presentation first briefly reviews robust optimization and scenario approaches that have been proposed to plan for systems under deep uncertainty. One recently introduced framework is Many Objective Robust Decision Making (MORDM). MORDM combines two techniques: evolutionary algorithm search is used to generate planning alternatives, and robust decision making methods are used to sample performance over a large range of plausible factors and, subsequently, choose a robust solution. Within MORDM, Pareto approximate tradeoff sets of solutions are used to balance objectives and examine alternatives. However, MORDM does not currently incorporate the deeply uncertain scenario information into the search process itself. In this presentation, we suggest several avenues for doing so, that are focused on modifying the suite of uncertain data that is selected within the search process. Visualizations that compare tradeoff sets across different sets of assumptions can be used to guide decision makers' learning and, ultimately, their selection of several candidate solutions for further planning. For example, the baseline assumptions about probability distributions can be compared to optimization results under severe events to determine adaptive management strategies. A case study of water planning in the Lower Rio Grande Valley (LRGV) in Texas is used to demonstrate the approach. Our LRGV results compare baseline optimization with new solution sets that examine optimal management strategies under scenarios characterized by lower than average

  14. Adaptive sparse signal processing of on-orbit lightning data using learned dictionaries

    NASA Astrophysics Data System (ADS)

    Moody, D. I.; Hamlin, T.; Light, T. E.; Loveland, R. C.; Smith, D. A.; Suszcynsky, D. M.

    2012-12-01

    For the past two decades, there has been an ongoing research effort at Los Alamos National Laboratory (LANL) to learn more about the Earth's radiofrequency (RF) background utilizing satellite-based RF observations of terrestrial lightning. Arguably the richest satellite lightning database ever recorded is that from the Fast On-orbit Recording of Transient Events (FORTE) satellite, which returned at least five years of data from its two RF payloads after launch in 1997. While some classification work has been done previously on the LANL FORTE RF database, application of modern pattern recognition techniques may further lightning research in the scientific community and potentially improve on-orbit processing and event discrimination capabilities for future satellite payloads. We now develop and implement new event classification capability on the FORTE database using state-of-the-art adaptive signal processing combined with compressive sensing and machine learning techniques. The focus of our work is improved feature extraction using sparse representations in learned dictionaries. Extracting classification features from RF signals typically relies on knowledge of the application domain in order to find feature vectors unique to a signal class and robust against background noise. Conventional localized data representations for RF transients using analytical dictionaries, such as a short-time Fourier basis or wavelets, can be suitable for analyzing some types of signals, but not others. Instead, we learn RF dictionaries directly from data, without relying on analytical constraints or additional knowledge about the signal characteristics, using several established machine learning algorithms. Sparse classification features are extracted via matching pursuit search over the learned dictionaries, and used in conjunction with a statistical classifier to distinguish between lightning types. We present preliminary results of our work and discuss classification performance

  15. Utility of adaptive control processing for the interpretation of digital mammograms.

    PubMed

    Jinnouchi, Mikako; Yabuuchi, Hidetake; Kubo, Makoto; Tokunaga, Eriko; Yamamoto, Hidetaka; Honda, Hiroshi

    2016-11-01

    Background Adaptive control processing for mammography (ACM) is a novel program that automatically sets up appropriate image-processing parameters for individual mammograms (MMGs) by analyzing the focal and whole breast histogram. Purpose To investigate whether ACM improves the image contrast of digital MMGs and whether it improves radiologists' diagnostic performance in reading of MMGs. Material and Methods One hundred normal cases for image quality assessment and another 100 cases (50 normal and 50 cancers) for observer performance assessment were enrolled. All mammograms were examined with and without ACM. Five radiologists assessed the intra- and extra-mammary contrast of 100 normal MMGs, and the mean scores of the intra- and extra-mammary contrast were compared between MMGs with and without ACM in both the dense and non-dense group. They classified 100 MMGs into BI-RADS categories 1-5, and were asked to rate the images on a scale of 0 to 100 for the likelihood of the presence of category 3-5 lesions in each breast. Detectability of breast cancer, reading time, and frequency of window adjustment were compared between MMGs with and without ACM. Results ACM improved the intra-mammary contrast in both the dense and non-dense group but degraded extra-mammary contrast in the dense group. There was no significant difference in detectability of breast cancer between MMGs with and without ACM. Frequency of window adjustment without ACM was significantly higher than that with ACM. Reading time without ACM was significantly longer than that with ACM. Conclusion ACM improves the image contrast of MMGs and shortens reading time.

  16. GCKP84-general chemical kinetics code for gas-phase flow and batch processes including heat transfer effects

    NASA Technical Reports Server (NTRS)

    Bittker, D. A.; Scullin, V. J.

    1984-01-01

    A general chemical kinetics code is described for complex, homogeneous ideal gas reactions in any chemical system. The main features of the GCKP84 code are flexibility, convenience, and speed of computation for many different reaction conditions. The code, which replaces the GCKP code published previously, solves numerically the differential equations for complex reaction in a batch system or one dimensional inviscid flow. It also solves numerically the nonlinear algebraic equations describing the well stirred reactor. A new state of the art numerical integration method is used for greatly increased speed in handling systems of stiff differential equations. The theory and the computer program, including details of input preparation and a guide to using the code are given.

  17. Reserve, thin form-factor, hypochlorite-based cells for powering portable systems: Manufacture (including MEMS processes), performance and characterization

    NASA Astrophysics Data System (ADS)

    Cardenas-Valencia, Andres M.; Biver, Carl J.; Langebrake, Larry

    This work focuses on fabrication routes and performance evaluation of thin form-factors, reserve cells, as a powering alternative for expendable and/or remotely operated systems. The catalytic decomposition of sodium hypochlorite solutions is revisited herein with two cost-effective anodes: zinc and aluminum. Aluminum, even though the most expensive of the utilized anodes, constituted cells with double the energy content (up to 55 Wh kg -1) than those fabricated with zinc. Even though the hypochlorite concentration in the solution limits the cells' operational life, attractive performances (1.0 V with a current of 10 mA) for the manufactured cells are obtained. It is shown that micro fabrication processes, allowing for close electrodes interspacing, provided high faradic and columbic efficiencies of up to 70 and 100%, respectively. Obtained specific energies (50-120 Wh kg -1) are in the same order of magnitude than batteries currently used for powering deployable systems. Experimental results show that a simple model that linearly relates over potentials and the electrical load, adequately describe all the cell designs. A mathematical model based on a kinetic-mechanistic scheme that relates the current output as a function of time agrees fairly well with results obtained activating cells with various concentrations of NaOCl solutions.

  18. [Realization of an adaptive method of simulating the process of temperature change of a cadaver on a microcomputer].

    PubMed

    Shved, E F; Novikov, P I; Vlasov, A Iu

    1989-01-01

    Programme based on mathematical model of the process of dead body temperature changing was developed for estimation of postmortem interval. Automatic retrieval of problem solution was performed on programmable microcalculators of "Electronica MK-61" type using adaptive approach. Diagnostical accuracy in case of dead body being preserved in permanent cooling conditions is +/- 3%.

  19. Life, Learning, and Standing Alone: The Adaptation Process of Wives of South Korean Students to New Circumstances.

    ERIC Educational Resources Information Center

    Jun, JuSung

    Adjustment experiences of South Korean graduate students' wives living in Georgia were examined from a feminist viewpoint. The adaptive process, its cultural meaning, and related social ramifications, was hypothesized to be an example of transformative learning. These two questions guided the study: (1) how did South Korean students' wives adapt…

  20. Designing Training for Temporal and Adaptive Transfer: A Comparative Evaluation of Three Training Methods for Process Control Tasks

    ERIC Educational Resources Information Center

    Kluge, Annette; Sauer, Juergen; Burkolter, Dina; Ritzmann, Sandrina

    2010-01-01

    Training in process control environments requires operators to be prepared for temporal and adaptive transfer of skill. Three training methods were compared with regard to their effectiveness in supporting transfer: Drill & Practice (D&P), Error Training (ET), and procedure-based and error heuristics training (PHT). Communication…

  1. Adaptive optics microscopy enhances image quality in deep layers of CLARITY processed brains of YFP-H mice

    NASA Astrophysics Data System (ADS)

    Reinig, Marc R.; Novack, Samuel W.; Tao, Xiaodong; Ermini, Florian; Bentolila, Laurent A.; Roberts, Dustin G.; MacKenzie-Graham, Allan; Godshalk, S. E.; Raven, M. A.; Kubby, Joel

    2016-03-01

    Optical sectioning of biological tissues has become the method of choice for three-dimensional histological analyses. This is particularly important in the brain were neurons can extend processes over large distances and often whole brain tracing of neuronal processes is desirable. To allow deeper optical penetration, which in fixed tissue is limited by scattering and refractive index mismatching, tissue-clearing procedures such as CLARITY have been developed. CLARITY processed brains have a nearly uniform refractive index and three-dimensional reconstructions at cellular resolution have been published. However, when imaging in deep layers at submicron resolution some limitations caused by residual refractive index mismatching become apparent, as the resulting wavefront aberrations distort the microscopic image. The wavefront can be corrected with adaptive optics. Here, we investigate the wavefront aberrations at different depths in CLARITY processed mouse brains and demonstrate the potential of adaptive optics to enable higher resolution and a better signal-to-noise ratio. Our adaptive optics system achieves high-speed measurement and correction of the wavefront with an open-loop control using a wave front sensor and a deformable mirror. Using adaptive optics enhanced microscopy, we demonstrate improved image quality wavefront, point spread function, and signal to noise in the cortex of YFP-H mice.

  2. Technology transfer for adaptation

    NASA Astrophysics Data System (ADS)

    Biagini, Bonizella; Kuhl, Laura; Gallagher, Kelly Sims; Ortiz, Claudia

    2014-09-01

    Technology alone will not be able to solve adaptation challenges, but it is likely to play an important role. As a result of the role of technology in adaptation and the importance of international collaboration for climate change, technology transfer for adaptation is a critical but understudied issue. Through an analysis of Global Environment Facility-managed adaptation projects, we find there is significantly more technology transfer occurring in adaptation projects than might be expected given the pessimistic rhetoric surrounding technology transfer for adaptation. Most projects focused on demonstration and early deployment/niche formation for existing technologies rather than earlier stages of innovation, which is understandable considering the pilot nature of the projects. Key challenges for the transfer process, including technology selection and appropriateness under climate change, markets and access to technology, and diffusion strategies are discussed in more detail.

  3. Visual Adaptation

    PubMed Central

    Webster, Michael A.

    2015-01-01

    Sensory systems continuously mold themselves to the widely varying contexts in which they must operate. Studies of these adaptations have played a long and central role in vision science. In part this is because the specific adaptations remain a powerful tool for dissecting vision, by exposing the mechanisms that are adapting. That is, “if it adapts, it's there.” Many insights about vision have come from using adaptation in this way, as a method. A second important trend has been the realization that the processes of adaptation are themselves essential to how vision works, and thus are likely to operate at all levels. That is, “if it's there, it adapts.” This has focused interest on the mechanisms of adaptation as the target rather than the probe. Together both approaches have led to an emerging insight of adaptation as a fundamental and ubiquitous coding strategy impacting all aspects of how we see. PMID:26858985

  4. Avoiding the Enumeration of Infeasible Elementary Flux Modes by Including Transcriptional Regulatory Rules in the Enumeration Process Saves Computational Costs.

    PubMed

    Jungreuthmayer, Christian; Ruckerbauer, David E; Gerstl, Matthias P; Hanscho, Michael; Zanghellini, Jürgen

    2015-01-01

    Despite the significant progress made in recent years, the computation of the complete set of elementary flux modes of large or even genome-scale metabolic networks is still impossible. We introduce a novel approach to speed up the calculation of elementary flux modes by including transcriptional regulatory information into the analysis of metabolic networks. Taking into account gene regulation dramatically reduces the solution space and allows the presented algorithm to constantly eliminate biologically infeasible modes at an early stage of the computation procedure. Thereby, computational costs, such as runtime, memory usage, and disk space, are extremely reduced. Moreover, we show that the application of transcriptional rules identifies non-trivial system-wide effects on metabolism. Using the presented algorithm pushes the size of metabolic networks that can be studied by elementary flux modes to new and much higher limits without the loss of predictive quality. This makes unbiased, system-wide predictions in large scale metabolic networks possible without resorting to any optimization principle.

  5. Avoiding the Enumeration of Infeasible Elementary Flux Modes by Including Transcriptional Regulatory Rules in the Enumeration Process Saves Computational Costs

    PubMed Central

    Jungreuthmayer, Christian; Ruckerbauer, David E.; Gerstl, Matthias P.; Hanscho, Michael; Zanghellini, Jürgen

    2015-01-01

    Despite the significant progress made in recent years, the computation of the complete set of elementary flux modes of large or even genome-scale metabolic networks is still impossible. We introduce a novel approach to speed up the calculation of elementary flux modes by including transcriptional regulatory information into the analysis of metabolic networks. Taking into account gene regulation dramatically reduces the solution space and allows the presented algorithm to constantly eliminate biologically infeasible modes at an early stage of the computation procedure. Thereby, computational costs, such as runtime, memory usage, and disk space, are extremely reduced. Moreover, we show that the application of transcriptional rules identifies non-trivial system-wide effects on metabolism. Using the presented algorithm pushes the size of metabolic networks that can be studied by elementary flux modes to new and much higher limits without the loss of predictive quality. This makes unbiased, system-wide predictions in large scale metabolic networks possible without resorting to any optimization principle. PMID:26091045

  6. Engineering Analysis of Intermediate Loop and Process Heat Exchanger Requirements to Include Configuration Analysis and Materials Needs

    SciTech Connect

    T.M. Lillo; R.L. Williamson; T.R. Reed; C.B. Davis; D.M. Ginosar

    2005-09-01

    The need to locate advanced hydrogen production facilities a finite distance away from a nuclear power source necessitates the need for an intermediate heat transport loop (IHTL). This IHTL must not only efficiently transport energy over distances up to 500 meters but must also be capable of operating at high temperatures (>850oC) for many years. High temperature, long term operation raises concerns of material strength, creep resistance and general material stability (corrosion resistance). IHTL design is currently in the initial stages. Many questions remain to be answered before intelligent design can begin. The report begins to look at some of the issues surrounding the main components of an IHTL. Specifically, a stress analysis of a compact heat exchanger design under expected operating conditions is reported. Also the results of a thermal analysis performed on two ITHL pipe configurations for different heat transport fluids are presented. The configurations consist of separate hot supply and cold return legs as well as annular design in which the hot fluid is carried in an inner pipe and the cold return fluids travels in the opposite direction in the annular space around the hot pipe. The effects of insulation configurations on pipe configuration performance are also reported. Finally, a simple analysis of two different process heat exchanger designs, one a tube in shell type and the other a compact or microchannel reactor are evaluated in light of catalyst requirements. Important insights into the critical areas of research and development are gained from these analyses, guiding the direction of future areas of research.

  7. Adaptation Duration Dissociates Category-, Image-, and Person-Specific Processes on Face-Evoked Event-Related Potentials

    PubMed Central

    Zimmer, Márta; Zbanţ, Adriana; Németh, Kornél; Kovács, Gyula

    2015-01-01

    Several studies demonstrated that face perception is biased by the prior presentation of another face, a phenomenon termed as face-related after-effect (FAE). FAE is linked to a neural signal-reduction at occipito-temporal areas and it can be observed in the amplitude modulation of the early event-related potential (ERP) components. Recently, macaque single-cell recording studies suggested that manipulating the duration of the adaptor makes the selective adaptation of different visual motion processing steps possible. To date, however, only a few studies tested the effects of adaptor duration on the electrophysiological correlates of human face processing directly. The goal of the current study was to test the effect of adaptor duration on the image-, identity-, and generic category-specific face processing steps. To this end, in a two-alternative forced choice familiarity decision task we used five adaptor durations (ranging from 200–5000 ms) and four adaptor categories: adaptor and test were identical images—Repetition Suppression (RS); adaptor and test were different images of the Same Identity (SameID); adaptor and test images depicted Different Identities (DiffID); the adaptor was a Fourier phase-randomized image (No). Behaviorally, a strong priming effect was observed in both accuracy and response times for RS compared with both DiffID and No. The electrophysiological results suggest that rapid adaptation leads to a category-specific modulation of P100, N170, and N250. In addition, both identity and image-specific processes affected the N250 component during rapid adaptation. On the other hand, prolonged (5000 ms) adaptation enhanced, and extended category-specific adaptation processes over all tested ERP components. Additionally, prolonged adaptation led to the emergence of image-, and identity-specific modulations on the N170 and P2 components as well. In other words, there was a clear dissociation among category, identity-, and image

  8. [On the issue of optimization of adaptation process to new environment taking into consideration climate and weather conditions].

    PubMed

    Tarasov, A V; Koldunov, I N; Rakhmanov, R S

    2014-01-01

    There are revealed the features in the registration of newly diagnosed morbidity in cases in the organized team out of number of persons constantly living in the conditions of Baltic Sea (Kaliningrad region), as well as in those coming from other parts of the Russian Federation. This stipulates the elaboration of measures for prevention of disadaptational shifts in the organism related with adaptational processes as well as the process of acclimatization.

  9. A Durbin-Watson serial correlation test for ARX processes via excited adaptive tracking

    NASA Astrophysics Data System (ADS)

    Bercu, Bernard; Portier, Bruno; Vazquez, Victor

    2015-12-01

    We propose a new statistical test for the residual autocorrelation in ARX adaptive tracking. The introduction of a persistent excitation in the adaptive tracking control allows us to build a bilateral statistical test based on the well-known Durbin-Watson statistic. We establish the almost sure convergence and the asymptotic normality for the Durbin-Watson statistic leading to a powerful serial correlation test. Numerical experiments illustrate the good performances of our statistical test procedure.

  10. Stereoscopic adapter based system using HMD and image processing software for supporting inner ear operations performed using operating microscope

    NASA Astrophysics Data System (ADS)

    Leśniewski, Marcin; Kujawińska, Malgorzata; Kucharski, Tomasz; Niemczyk, Kazimierz

    2006-02-01

    Recently surgery requires extensive support from imaging technologies in order to increase effectiveness and safety of operations. One of important tasks is to enhance visualisation of quasi-phase (transparent) 3D structures. In this paper authors present a few of practical hardware solutions using of operational stereoscopic microscope with two image acquisition channels, stereoscopic adapter and Helmet Mounted Display (HMD) for stereoscopic visualization of operational field "in real time". Special attention is paid to the development of opto- mechanical unit. The authors focus on searching cheap, accurate and ergonomic solutions. A few proposals are analyzed: typical stereoscopic adapter with two image acquisition channels equipped with developed software for image low contrast enhancement for stereoscopic observation in stereoscopic HMD of operational field, visual - picture adapter (real operational view through microscope channels or processed operational field images observation in "real time").

  11. Carbon-dioxide storage in the subsurface: towards an understanding of crack development in the cap-rock including phase transition processes

    NASA Astrophysics Data System (ADS)

    Häberle, K.; Ehlers, W.

    2012-04-01

    Supercritical CO2 can be injected into deep saline aquifers to reduce the amount of CO2 in the atmosphere and thus, lessen the impact on the global warming. Qualified reservoirs should be in a sufficient depth to guarantee the thermodynamical environment for the supercritical state of CO2. Furthermore, an impermeable cap-rock layer must confine the reservoir layer, in order to collect the CO2 in the desired region. In CO2 storage it is crucial to guarantee the safety of the storage site and to eliminate possibilities of leakage. Therefore, deformation processes of the rock matrix and the cap-rock layer, which might be induced by the high pressure injection of CO2, must be investigated. The increase in stress may also cause crack development in the cap-rock layer. These could either be new developing fractures or the break-up of already existing but cemented cracks or faults. If such cracks occur, CO2 could migrate to shallower regions where the temperature and pressure cannot support the supercritical condition of the CO2 anymore. Thus, it is important to describe the phase transition process between supercritical, liquid and gaseous CO2. This requires a proper understanding of the thermodynamical behaviour of CO2 within the reservoir. The Theory of Porous Media (TPM) provides a useful continuum-mechanical basis to describe real natural systems in a thermodynamically consistent way. Hence, the TPM is applied to model multiphasic flow of CO2 and water and include elasto-plastic solid deformations of the porous matrix. The Peng-Robinson equation is implemented as a cubic equation of state to describe the phase behaviour of CO2 in the liquid, gaseous and supercritical region. However, in the two-phase region the isotherms show a horizontal section and kinks at the boiling and vapour curve. This cannot be represented by a continuously differentiable function such as the Peng-Robinson equation. To circumvent this problem, the Antoine equation provides additional

  12. Functional adaptation to oxidative stress by memory T cells: an analysis of the role in the cardiovascular disease process.

    PubMed

    Elahi, Maqsood M; Matata, Bashir M

    2008-11-21

    T cells participate in combating infection and critically determine the outcomes in any given disease process. Impaired immune response occurs in a number disease processes such as in cancer and atherosclerosis although the underlying mechanisms are still not fully understood. This article gives an up-to-date review of T cells development and functional adaptation to pathophysiological stimuli and participation in the cardiovascular disease process. In addition, we have discussed the signaling pathways controlled by the microenvironment that determine T cells function and resultant type of immune response. We have also discussed in detail how oxidative stress is a key component of the micro environmental interaction.

  13. Internet-usage patterns of immigrants in the process of intercultural adaptation.

    PubMed

    Chen, Wenli

    2010-08-01

    This paper investigates Internet-usage patterns of immigrants, and seeks to identify the correlation between Internet use and intercultural adaptation. The study focuses on mainland Chinese immigrants in Singapore, and was conducted via a nationwide telephone survey. The results show that immigrants tend to change their preferences on Internet use to reflect their residence in the host country. In particular, the longer an immigrant resides in the host country, the less likely they would be to surf their original country's websites and the more likely they would be to communicate with local people via the Internet. More importantly, differences in Internet usage are found to have a significant impact on immigrants' intercultural adaptation. In an online environment, the social communication in the host country is a critical component that can facilitate or impede immigrants' successful adaptation to the host country, whereas ethnic social communication also plays a role at the initial stage of transition.

  14. Hypermedia Environments and Adaptive Instruction.

    ERIC Educational Resources Information Center

    Federico, Pat-Anthony

    1999-01-01

    Reviews relevant professional literature concerning hypermedia environments and adaptive instruction for online learning for distance education and continuing education. Highlights include aptitude-treatment interaction; cognitive processes; navigational paths; log files; and intelligent tutors. Contains 125 references. (LRW)

  15. Simpler Adaptive Optics using a Single Device for Processing and Control

    NASA Astrophysics Data System (ADS)

    Zovaro, A.; Bennet, F.; Rye, D.; D'Orgeville, C.; Rigaut, F.; Price, I.; Ritchie, I.; Smith, C.

    The management of low Earth orbit is becoming more urgent as satellite and debris densities climb, in order to avoid a Kessler syndrome. A key part of this management is to precisely measure the orbit of both active satellites and debris. The Research School of Astronomy and Astrophysics at the Australian National University have been developing an adaptive optics (AO) system to image and range orbiting objects. The AO system provides atmospheric correction for imaging and laser ranging, allowing for the detection of smaller angular targets and drastically increasing the number of detectable objects. AO systems are by nature very complex and high cost systems, often costing millions of dollars and taking years to design. It is not unusual for AO systems to comprise multiple servers, digital signal processors (DSP) and field programmable gate arrays (FPGA), with dedicated tasks such as wavefront sensor data processing or wavefront reconstruction. While this multi-platform approach has been necessary in AO systems to date due to computation and latency requirements, this may no longer be the case for those with less demanding processing needs. In recent years, large strides have been made in FPGA and microcontroller technology, with todays devices having clock speeds in excess of 200 MHz whilst using a < 5 V power supply. AO systems using a single such device for all data processing and control may present a far simpler, cheaper, smaller and more efficient solution than existing systems. A novel AO system design based around a single, low-cost controller is presented. The objective is to determine the performance which can be achieved in terms of bandwidth and correction order, with a focus on optimisation and parallelisation of AO algorithms such as wavefront measurement and reconstruction. The AO system consists of a Shack-Hartmann wavefront sensor and a deformable mirror to correct light from a 1.8 m telescope for the purpose of imaging orbiting satellites. The

  16. Reconfigurable environmentally adaptive computing

    NASA Technical Reports Server (NTRS)

    Coxe, Robin L. (Inventor); Galica, Gary E. (Inventor)

    2008-01-01

    Described are methods and apparatus, including computer program products, for reconfigurable environmentally adaptive computing technology. An environmental signal representative of an external environmental condition is received. A processing configuration is automatically selected, based on the environmental signal, from a plurality of processing configurations. A reconfigurable processing element is reconfigured to operate according to the selected processing configuration. In some examples, the environmental condition is detected and the environmental signal is generated based on the detected condition.

  17. Dual mode adaptive fractional order PI controller with feedforward controller based on variable parameter model for quadruple tank process.

    PubMed

    Roy, Prasanta; Roy, Binoy Krishna

    2016-07-01

    The Quadruple Tank Process (QTP) is a well-known benchmark of a nonlinear coupled complex MIMO process having both minimum and nonminimum phase characteristics. This paper presents a novel self tuning type Dual Mode Adaptive Fractional Order PI controller along with an Adaptive Feedforward controller for the QTP. The controllers are designed based on a novel Variable Parameter Transfer Function model. The effectiveness of the proposed model and controllers is tested through numerical simulation and experimentation. Results reveal that the proposed controllers work successfully to track the reference signals in all ranges of output. A brief comparison with some of the earlier reported similar works is presented to show that the proposed control scheme has some advantages and better performances than several other similar works.

  18. Effects of Class Size and Adaptive Teaching Competency on Classroom Processes and Academic Outcome

    ERIC Educational Resources Information Center

    Bruhwiler, Christian; Blatchford, Peter

    2011-01-01

    In many studies of class size effects, teacher characteristics are missing, even though many argue it is not class size that is important but teacher quality. In the present study teachers' effectiveness on the learning progress was assessed while teaching a unit with predefined learning objectives. To measure adaptive teaching competency a…

  19. ADAPTIVE WATER SENSOR SIGNAL PROCESSING: EXPERIMENTAL RESULTS AND IMPLICATIONS FOR ONLINE CONTAMINANT WARNING SYSTEMS

    EPA Science Inventory

    A contaminant detection technique and its optimization algorithms have two principal functions. One is the adaptive signal treatment that suppresses background noise and enhances contaminant signals, leading to a promising detection of water quality changes at a false rate as low...

  20. The Emotions of Socialization-Related Learning: Understanding Workplace Adaptation as a Learning Process.

    ERIC Educational Resources Information Center

    Reio, Thomas G., Jr.

    The influence of selected discrete emotions on socialization-related learning and perception of workplace adaptation was examined in an exploratory study. Data were collected from 233 service workers in 4 small and medium-sized companies in metropolitan Washington, D.C. The sample members' average age was 32.5 years, and the sample's racial makeup…

  1. Adaptive Memory: Ancestral Priorities and the Mnemonic Value of Survival Processing

    ERIC Educational Resources Information Center

    Nairne, James S.; Pandeirada, Josefa N. S.

    2010-01-01

    Evolutionary psychologists often propose that humans carry around "stone-age" brains, along with a toolkit of cognitive adaptations designed originally to solve hunter-gatherer problems. This perspective predicts that optimal cognitive performance might sometimes be induced by ancestrally-based problems, those present in ancestral environments,…

  2. Can Survival Processing Enhance Story Memory? Testing the Generalizability of the Adaptive Memory Framework

    ERIC Educational Resources Information Center

    Seamon, John G.; Bohn, Justin M.; Coddington, Inslee E.; Ebling, Maritza C.; Grund, Ethan M.; Haring, Catherine T.; Jang, Sue-Jung; Kim, Daniel; Liong, Christopher; Paley, Frances M.; Pang, Luke K.; Siddique, Ashik H.

    2012-01-01

    Research from the adaptive memory framework shows that thinking about words in terms of their survival value in an incidental learning task enhances their free recall relative to other semantic encoding strategies and intentional learning (Nairne, Pandeirada, & Thompson, 2008). We found similar results. When participants used incidental…

  3. Rational Adaptation under Task and Processing Constraints: Implications for Testing Theories of Cognition and Action

    ERIC Educational Resources Information Center

    Howes, Andrew; Lewis, Richard L.; Vera, Alonso

    2009-01-01

    The authors assume that individuals adapt rationally to a utility function given constraints imposed by their cognitive architecture and the local task environment. This assumption underlies a new approach to modeling and understanding cognition--cognitively bounded rational analysis--that sharpens the predictive acuity of general, integrated…

  4. Facial Emotion Processing and Social Adaptation in Adults with and without Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Garcia-Villamisar, Domingo; Rojahn, Johannes; Zaja, Rebecca H.; Jodra, Marina

    2010-01-01

    Individuals with autism spectrum disorder (ASD) and individuals with intellectual disabilities without ASD have limited facial emotion recognition abilities, which may adversely impact social adjustment and other adaptive behavior. This study was designed to examine this relationship in adults with and without ASD. Two groups of adults with…

  5. An Evolving Simulation/Gaming Process to Facilitate Adaptive Watershed Management in Northern Mountainous Thailand

    ERIC Educational Resources Information Center

    Barnaud, Cecile; Promburom, Tanya; Trebuil, Guy; Bousquet, Francois

    2007-01-01

    The decentralization of natural resource management provides an opportunity for communities to increase their participation in related decision making. Research should propose adapted methodologies enabling the numerous stakeholders of these complex socioecological settings to define their problems and identify agreed-on solutions. This article…

  6. Considerations of Dance Transmission Processes: Adapting Bharata Natyam in a Singapore Primary School

    ERIC Educational Resources Information Center

    Lum, Chee Hoo; Gonda, Donn Emmanuel

    2014-01-01

    This qualitative case study has, for its purpose, an examination of the pedagogies and practices of a master Bharata Natyam dance instructor working within a Singapore primary school context. It explores the instructor's adaptation within an after-school weekly activity of the South Indian traditional classical dance form. Considerations of dance…

  7. The Adaptation Process of Families with Children with Intellectual Disabilities in Catalonia

    ERIC Educational Resources Information Center

    Mas, Joana Maria; Giné, Climent; McWilliam, Robin A.

    2016-01-01

    The most important adaptation task that all families must undertake is the construction of a sustainable, meaningful, and congruent daily routine of family life (R. Gallimore, T. Weisner, L. Bernheimer, D. Guthrie, & K. Nihira, 1993). The aim of this mixed-method study was to understand, from the perspective of parents, how families adapt…

  8. Photoreceptor Processing Speed and Input Resistance Changes during Light Adaptation Correlate with Spectral Class in the Bumblebee, Bombus impatiens

    PubMed Central

    Skorupski, Peter; Chittka, Lars

    2011-01-01

    Colour vision depends on comparison of signals from photoreceptors with different spectral sensitivities. However, response properties of photoreceptor cells may differ in ways other than spectral tuning. In insects, for example, broadband photoreceptors, with a major sensitivity peak in the green region of the spectrum (>500 nm), drive fast visual processes, which are largely blind to chromatic signals from more narrowly-tuned photoreceptors with peak sensitivities in the blue and UV regions of the spectrum. In addition, electrophysiological properties of the photoreceptor membrane may result in differences in response dynamics of photoreceptors of similar spectral class between species, and different spectral classes within a species. We used intracellular electrophysiological techniques to investigate response dynamics of the three spectral classes of photoreceptor underlying trichromatic colour vision in the bumblebee, Bombus impatiens, and we compare these with previously published data from a related species, Bombus terrestris. In both species, we found significantly faster responses in green, compared with blue- or UV-sensitive photoreceptors, although all 3 photoreceptor types are slower in B. impatiens than in B. terrestris. Integration times for light-adapted B. impatiens photoreceptors (estimated from impulse response half-width) were 11.3±1.6 ms for green photoreceptors compared with 18.6±4.4 ms and 15.6±4.4 for blue and UV, respectively. We also measured photoreceptor input resistance in dark- and light-adapted conditions. All photoreceptors showed a decrease in input resistance during light adaptation, but this decrease was considerably larger (declining to about 22% of the dark value) in green photoreceptors, compared to blue and UV (41% and 49%, respectively). Our results suggest that the conductances associated with light adaptation are largest in green photoreceptors, contributing to their greater temporal processing speed. We suggest that the

  9. Proteomic evidence of a paedomorphic evolutionary process within a marine snail species: a strategy for adapting to extreme ecological conditions?

    PubMed

    Diz, A P; Páez de la Cadena, M; Rolán-Alvarez, E

    2012-12-01

    The exposed and sheltered ecotypes of the marine snail Littorina saxatilis from European rocky shores are considered a key model system to study adaptation and ecological speciation. Previous studies showed that two ecotypes (RB and SU) of this species in NW Spain have adapted differently to different shore levels and microhabitats. In order to understand how this divergent adaptive process has been accomplished, we followed a quantitative proteomic approach to investigate the proteome variation in a number of different biological factors, that is, ecotype, ontogeny and their interactions. This approach allowed testing the hypothesis that one of the ecotypes has evolved by paedomorphosis, and also whether or not the molecular mechanisms related to ecotype differentiation are set up in early developmental stages. Additionally, the identification of some candidate proteins using mass spectrometry provides some functional insights into these evolutionary processes. Results from this study provided evidence of higher ontogenetic differentiation at proteome level in the RB (metamorphic) than in SU (paedomorphic) ecotype that point to the possibility of juvenile stage retention in this latter ecotype. The level of protein expression (proteome) differences between ecotypes maintained nearly constant from late embryonic stages to adulthood, although some proteins involved in these changes considerably differed in embryonic compared to other ontogenetic stages. Paedomorphosis may be the evolutionary response of the SU ecotype of solving the trade-off during sexually immaturity that is caused by the evolution of small size arising from adaptation to the wave-exposed habitat. Some potential candidate genes of adaptation related to energetic metabolism have been identified, providing a promising baseline for future functional analyses.

  10. Global VTEC-modelling in near real-time based on space geodetic techniques, adapted B-spline expansions and Kalman-filtering including observations of the Sun's radiation

    NASA Astrophysics Data System (ADS)

    Börger, Klaus; Schmidt, Michael; Dettmering, Denise; Limberger, Marco; Erdogan, Eren; Seitz, Florian; Brandert, Sylvia; Görres, Barbara; Kersten, Wilhelm; Bothmer, Volker; Hinrichs, Johannes; Venzmer, Malte; Mrotzek, Niclas

    2016-04-01

    Today, the observations of space geodetic techniques are usually available with a rather low latency which applies to space missions observing the solar terrestrial environment, too. Therefore, we can use all these measurements in near real-time to compute and to provide ionosphere information, e.g. the vertical total electron content (VTEC). GSSAC and BGIC support a project aiming at a service for providing ionosphere information. This project is called OPTIMAP, meaning "Operational Tool for Ionosphere Mapping and Prediction"; the scientific work is mainly done by the German Geodetic Research Institute of the Technical University Munich (DGFI-TUM) and the Institute for Astrophysics of the University of Goettingen (IAG). The OPTIMAP strategy for providing ionosphere target quantities of high quality, such as VTEC or the electron density, includes mathematical approaches and tools allowing for the model adaptation to the real observational scenario as a significant improvement w.r.t. the traditional well-established methods. For example, OPTIMAP combines different observation types such as GNSS (GPS, GLONASS), Satellite Altimetry (Jason-2), DORIS as well as radio-occultation measurements (FORMOSAT#3/COSMIC). All these observations run into a Kalman-filter to compute global ionosphere maps, i.e. VTEC, for the current instant of time and as a forecast for a couple of subsequent days. Mathematically, the global VTEC is set up as a series expansion in terms of two-dimensional basis functions defined as tensor products of trigonometric B-splines for longitude and polynomial B-splines for latitude. Compared to the classical spherical harmonics, B-splines have a localizing character and, therefore, can handle an inhomogeneous data distribution properly. Finally, B-splines enable a so-called multi-resolution-representation (MRR) enabling the combination of global and regional modelling approaches. In addition to the geodetic measurements, Sun observations are pre-processed

  11. Developing Coastal Adaptation to Climate Change in the New York City Infrastructure-Shed: Process, Approach, Tools, and Strategies

    NASA Technical Reports Server (NTRS)

    Rosenzweig, Cynthia; Solecki, William D.; Blake, Reginald; Bowman, Malcolm; Faris, Craig; Gornitz, Vivien; Horton, Radley; Jacob, Klaus; LeBlanc, Alice; Leichenko, Robin; Linkin, Megan; Major, David; O'Grady, Megan; Patrick, Lesley; Sussman, Edna; Yohe, Gary; Zimmerman, Rae

    2010-01-01

    While current rates of sea level rise and associated coastal flooding in the New York City region appear to be manageable by stakeholders responsible for communications, energy, transportation, and water infrastructure, projections for sea level rise and associated flooding in the future, especially those associated with rapid icemelt of the Greenland and West Antarctic Icesheets, may be beyond the range of current capacity because an extreme event might cause flooding and inundation beyond the planning and preparedness regimes. This paper describes the comprehensive process, approach, and tools developed by the New York City Panel on Climate Change (NPCC) in conjunction with the region s stakeholders who manage its critical infrastructure, much of which lies near the coast. It presents the adaptation approach and the sea-level rise and storm projections related to coastal risks developed through the stakeholder process. Climate change adaptation planning in New York City is characterized by a multi-jurisdictional stakeholder-scientist process, state-of-the-art scientific projections and mapping, and development of adaptation strategies based on a risk-management approach.

  12. [An increase in efficiency of adaptations and a weakening of organism protective reactions in the process of biological evolution].

    PubMed

    2014-01-01

    The main direction of evolution of living organisms is development of the central nervous system and sense organ, an increase of energy exchange development of homoiothermia, development of the more and more complex forms of behavior, an increase in energy expenditure in connection with an increase of the organism activity, and development of adaptation to the habitat. Such fundamental processes were subjected and have been subjected to numerous studies and discussions. However, in different animals there exist different species peculiarities of evolution of physiological functions, from which finally formed are fundamental evolutionary processes. We studied some of these specific processes by dividing them into two categories. The first category is "Increase of efficiency of adaptation" in development of biological evolution. By this term we mean development of amazing by perfection specific physiological mechanisms of adaptive character. The second category is "Weakening of protective organism reactions". By this we understand disturbance of protective mechanisms of the organism immune system, discoordination of movement of leukocytes along microvessels, the absence of efficient collateral circulation in brain and in heart, etc.

  13. Multilevel adaptive process control of acquisition and post-processing of computed radiographic images in picture archiving and communication system environment.

    PubMed

    Zhang, J; Huang, H K

    1998-01-01

    Computed radiography (CR) has become a widely used imaging modality replacing the conventional screen/film procedure in diagnostic radiology. After a latent image is captured in a CR imaging plate, there are seven key processes required before a CR image can be reliably archived and displayed in a picture archiving and communication system (PACS) environment. Human error, computational bottlenecks, software bugs, and CR system errors often crash the CR acquisition and post-processing computers which results in a delay of transmitting CR images for proper viewing at the workstation. In this paper, we present a control theory and a fault tolerance algorithm, as well as their implementation in the PACS environment to circumvent such problems. The software implementation of the control theory and the algorithm is based on the event-driven, multilevel adaptive processing structure. The automated software has been used to provide real-time monitoring and control of CR image acquisition and post-processing in the intensive care unit module of the PACS operation at the University of California, San Francisco. Results demonstrate that the multilevel adaptive process control structure improves CR post-processing time, increases the reliability of the CR images delivery, minimizes user intervention, and speeds up the previously time-consuming quality assurance procedure.

  14. An Investigation of Adaptive Signal Processing Approaches to Active Combustion Control

    DTIC Science & Technology

    2001-06-01

    stabilizing control using an adaptive feedback architecture. As discussed by Annaswamy et al. (1998), previous researchers have not been able to...accurately represents the dynamics of the limit cycling system and can ultimately be used for stabilizing control . System Identification The approach to...achieve stabilizing control . The first is easily identifiable as a feedback loop instability (see Equation 4), whereas the second is less well-defined as a

  15. Adaptive Computer Aiding in Dynamic Decision Processes: An Experimental Study of Aiding Effectiveness

    DTIC Science & Technology

    1975-05-01

    and a larger subject group. 1-2 Adaptive Decision Aiding 1-2 The primary function of ADDAM is not simply to model the decision maker’s behavior...maximum expected utility (OEVMAXEU) during the course of the test session was the primary measure of decision performance. As a group, the aided...in Chapter 3. The primary function of ADDAM is not simply to model the decision maker’s behavior but to provide a basis for decision aiding. Once

  16. A NOISE ADAPTIVE FUZZY EQUALIZATION METHOD FOR PROCESSING SOLAR EXTREME ULTRAVIOLET IMAGES

    SciTech Connect

    Druckmueller, M.

    2013-08-15

    A new image enhancement tool ideally suited for the visualization of fine structures in extreme ultraviolet images of the corona is presented in this paper. The Noise Adaptive Fuzzy Equalization method is particularly suited for the exceptionally high dynamic range images from the Atmospheric Imaging Assembly instrument on the Solar Dynamics Observatory. This method produces artifact-free images and gives significantly better results than methods based on convolution or Fourier transform which are often used for that purpose.

  17. Adapting the Reconfigurable SpaceCube Processing System for Multiple Mission Applications

    NASA Technical Reports Server (NTRS)

    Petrick, Dave

    2014-01-01

    This paper will detail the use of SpaceCube in multiple space flight applications including the Hubble Space Telescope Servicing Mission 4 (HST-SM4), an International Space Station (ISS) radiation test bed experiment, and the main avionics subsystem for two separate ISS attached payloads. Each mission has had varying degrees of data processing complexities, performance requirements, and external interfaces. We will show the methodology used to minimize the changes required to the physical hardware, FPGA designs, embedded software interfaces, and testing.This paper will summarize significant results as they apply to each mission application. In the HST-SM4 application we utilized the FPGA resources to accelerate portions of the image processing algorithms more than 25 times faster than a standard space processor in order to meet computational speed requirements. For the ISS radiation on-orbit demonstration, the main goal is to show that we can rely on the commercial FPGAs and processors in a space environment. We describe our FPGA and processor radiation mitigation strategies that have resulted in our eight PowerPCs being available and error free for more than 99.99 of the time over the period of four years. This positive data and proven reliability of the SpaceCube on ISS resulted in the Department of Defense (DoD) selecting SpaceCube, which is replacing an older and slower computer currently used on ISS, as the main avionics for two upcoming ISS experiment campaigns. This paper will show how we quickly reconfigured the SpaceCube system to meet the more stringent reliability requirements

  18. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification

    PubMed Central

    Tenzer, Stefan; Crawford, Hayley; Pymm, Phillip; Gifford, Robert; Sreenu, Vattipally B.; Weimershaus, Mirjana; de Oliveira, Tulio; Burgevin, Anne; Gerstoft, Jan; Akkad, Nadja; Lunn, Daniel; Fugger, Lars; Bell, John; Schild, Hansjörg; van Endert, Peter; Iversen, Astrid K.N.

    2014-01-01

    Summary The recent HIV-1 vaccine failures highlight the need to better understand virus-host interactions. One key question is why CD8+ T cell responses to two HIV-Gag regions are uniquely associated with delayed disease progression only in patients expressing a few rare HLA class I variants when these regions encode epitopes presented by ∼30 more common HLA variants. By combining epitope processing and computational analyses of the two HIV subtypes responsible for ∼60% of worldwide infections, we identified a hitherto unrecognized adaptation to the antigen-processing machinery through substitutions at subtype-specific motifs. Multiple HLA variants presenting epitopes situated next to a given subtype-specific motif drive selection at this subtype-specific position, and epitope abundances correlate inversely with the HLA frequency distribution in affected populations. This adaptation reflects the sum of intrapatient adaptations, is predictable, facilitates viral subtype diversification, and increases global HIV diversity. Because low epitope abundance is associated with infrequent and weak T cell responses, this most likely results in both population-level immune evasion and inadequate responses in most people vaccinated with natural HIV-1 sequence constructs. Our results suggest that artificial sequence modifications at subtype-specific positions in vitro could refocus and reverse the poor immunogenicity of HIV proteins. PMID:24726370

  19. Erosive processes after tectonic uplift stimulate vicariant and adaptive speciation: evolution in an Afrotemperate-endemic paper daisy genus

    PubMed Central

    2014-01-01

    Background The role of tectonic uplift in stimulating speciation in South Africa’s only alpine zone, the Drakensberg, has not been explicitly examined. Tectonic processes may influence speciation both through the creation of novel habitats and by physically isolating plant populations. We use the Afrotemperate endemic daisy genus Macowania to explore the timing and mode (geographic versus adaptive) of speciation in this region. Between sister species pairs we expect high morphological divergence where speciation has happened in sympatry (adaptive) while with geographic (vicariant) speciation we may expect to find less morphological divergence and a greater degree of allopatry. A dated molecular phylogenetic hypothesis for Macowania elucidates species’ relationships and is used to address the potential impact of uplift on diversification. Morphological divergence of a small sample of reproductive and vegetative characters, used as a proxy for adaptive divergence, is measured against species’ range distributions to estimate mode of speciation across two subclades in the genus. Results The Macowania crown age is consistent with the hypothesis of post-uplift diversification, and we find evidence for both vicariant and adaptive speciation between the two subclades within Macowania. Both subclades exhibit strong signals of range allopatry, suggesting that geographic isolation was important in speciation. One subclade, associated with dry, rocky environments at high altitudes, shows very little morphological and ecological differentiation but high range allopatry. The other subclade occupies a greater variety of habitats and exhibits far greater morphological differentiation, but contains species with overlapping distribution ranges. Conclusions Species in Macowania are likely to have diversified in response to tectonic uplift, and we invoke uplift and uplift-mediated erosion as the main drivers of speciation. The greater relative morphological divergence in

  20. Effects of single cortisol administrations on human affect reviewed: Coping with stress through adaptive regulation of automatic cognitive processing.

    PubMed

    Putman, Peter; Roelofs, Karin

    2011-05-01

    The human stress hormone cortisol may facilitate effective coping after psychological stress. In apparent agreement, administration of cortisol has been demonstrated to reduce fear in response to stressors. For anxious patients with phobias or posttraumatic stress disorder this has been ascribed to hypothetical inhibition of retrieval of traumatic memories. However, such stress-protective effects may also work via adaptive regulation of early cognitive processing of threatening information from the environment. This paper selectively reviews the available literature on effects of single cortisol administrations on affect and early cognitive processing of affectively significant information. The concluded working hypothesis is that immediate effects of high concentration of cortisol may facilitate stress-coping via inhibition of automatic processing of goal-irrelevant threatening information and through increased automatic approach-avoidance responses in early emotional processing. Limitations in the existing literature and suggestions for future directions are briefly discussed.

  1. The association of physical activity to neural adaptability during visuo-spatial processing in healthy elderly adults: A multiscale entropy analysis.

    PubMed

    Wang, Chun-Hao; Tsai, Chia-Liang; Tseng, Philip; Yang, Albert C; Lo, Men-Tzung; Peng, Chung-Kang; Wang, Hsin-Yi; Muggleton, Neil G; Juan, Chi-Hung; Liang, Wei-Kuang

    2014-10-29

    Physical activity has been shown to benefit brain and cognition in late adulthood. However, this effect is still unexplored in terms of brain signal complexity, which reflects the level of neural adaptability and efficiency during cognitive processing that cannot be acquired via averaged neuroelectric signals. Here we employed multiscale entropy analysis (MSE) of electroencephalography (EEG), a new approach that conveys important information related to the temporal dynamics of brain signal complexity across multiple time scales, to reveal the association of physical activity with neural adaptability and efficiency in elderly adults. A between-subjects design that included 24 participants (aged 66.63±1.31years; female=12) with high physical activity and 24 age- and gender-matched low physical activity participants (aged 67.29±1.20years) was conducted to examine differences related to physical activity in performance and MSE of EEG signals during a visuo-spatial cognition task. We observed that physically active elderly adults had better accuracy on both visuo-spatial attention and working memory conditions relative to their sedentary counterparts. Additionally, these physically active elderly adults displayed greater MSE values at larger time scales at the Fz electrode in both attention and memory conditions. The results suggest that physical activity may be beneficial for adaptability of brain systems in tasks involving visuo-spatial information. MSE thus might be a promising approach to test the effects of the benefits of exercise on cognition.

  2. Reinforcement learning for partially observable dynamic processes: adaptive dynamic programming using measured output data.

    PubMed

    Lewis, F L; Vamvoudakis, Kyriakos G

    2011-02-01

    Approximate dynamic programming (ADP) is a class of reinforcement learning methods that have shown their importance in a variety of applications, including feedback control of dynamical systems. ADP generally requires full information about the system internal states, which is usually not available in practical situations. In this paper, we show how to implement ADP methods using only measured input/output data from the system. Linear dynamical systems with deterministic behavior are considered herein, which are systems of great interest in the control system community. In control system theory, these types of methods are referred to as output feedback (OPFB). The stochastic equivalent of the systems dealt with in this paper is a class of partially observable Markov decision processes. We develop both policy iteration and value iteration algorithms that converge to an optimal controller that requires only OPFB. It is shown that, similar to Q -learning, the new methods have the important advantage that knowledge of the system dynamics is not needed for the implementation of these learning algorithms or for the OPFB control. Only the order of the system, as well as an upper bound on its "observability index," must be known. The learned OPFB controller is in the form of a polynomial autoregressive moving-average controller that has equivalent performance with the optimal state variable feedback gain.

  3. Proprioceptive sensibility in the elderly: degeneration, functional consequences and plastic-adaptive processes.

    PubMed

    Goble, Daniel J; Coxon, James P; Wenderoth, Nicole; Van Impe, Annouchka; Swinnen, Stephan P

    2009-03-01

    As the percentage of individuals over the age of 60 years continues to rise, determining the extent and functional significance of age-related declines in sensorimotor performance is of increasing importance. This review examines the specific contribution of proprioceptive feedback to sensorimotor performance in older adults. First, a global perspective of proprioceptive acuity is provided assimilating information from studies where only one of several aspects of proprioceptive function (e.g. sense of position, motion or dynamic position) was quantified, and/or a single joint or limb segment tested. Second, the consequences of proprioceptive deficits are established with particular emphasis placed on postural control. Lastly, the potential for plastic changes in the aging proprioceptive system is highlighted, including studies which relate physical activity to enhanced proprioceptive abilities in older adults. Overall, this review provides a foundation for future studies regarding the proprioceptive feedback abilities of elderly individuals. Such studies may lead to greater advances in the treatment and prevention of the sensorimotor deficits typically associated with the aging process.

  4. Community-based Participatory Process – Climate Change and Health Adaptation Program for Northern First Nations and Inuit in Canada

    PubMed Central

    Peace, Diane McClymont; Myers, Erin

    2012-01-01

    Objectives Health Canada's Program for Climate Change and Health Adaptation in Northern First Nation and Inuit Communities is unique among Canadian federal programs in that it enables community-based participatory research by northern communities. Study design The program was designed to build capacity by funding communities to conduct their own research in cooperation with Aboriginal associations, academics, and governments; that way, communities could develop health-related adaptation plans and communication materials that would help in adaptation decision-making at the community, regional, national and circumpolar levels with respect to human health and a changing environment. Methods Community visits and workshops were held to familiarize northerners with the impacts of climate change on their health, as well as methods to develop research proposals and budgets to meet program requirements. Results Since the launch of the Climate Change and Health Adaptation Program in 2008, Health Canada has funded 36 community projects across Canada's North that focus on relevant health issues caused by climate change. In addition, the program supported capacity-building workshops for northerners, as well as a Pan-Arctic Results Workshop to bring communities together to showcase the results of their research. Results include: numerous films and photo-voice products that engage youth and elders and are available on the web; community-based ice monitoring, surveillance and communication networks; and information products on land, water and ice safety, drinking water, food security and safety, and traditional medicine. Conclusions Through these efforts, communities have increased their knowledge and understanding of the health effects related to climate change and have begun to develop local adaptation strategies. PMID:22584509

  5. Application of Bayesian techniques to model the burden of human salmonellosis attributable to U.S. food commodities at the point of processing: adaptation of a Danish model.

    PubMed

    Guo, Chuanfa; Hoekstra, Robert M; Schroeder, Carl M; Pires, Sara Monteiro; Ong, Kanyin Liane; Hartnett, Emma; Naugle, Alecia; Harman, Jane; Bennett, Patricia; Cieslak, Paul; Scallan, Elaine; Rose, Bonnie; Holt, Kristin G; Kissler, Bonnie; Mbandi, Evelyne; Roodsari, Reza; Angulo, Frederick J; Cole, Dana

    2011-04-01

    Mathematical models that estimate the proportion of foodborne illnesses attributable to food commodities at specific points in the food chain may be useful to risk managers and policy makers to formulate public health goals, prioritize interventions, and document the effectiveness of mitigations aimed at reducing illness. Using human surveillance data on laboratory-confirmed Salmonella infections from the Centers for Disease Control and Prevention and Salmonella testing data from U.S. Department of Agriculture Food Safety and Inspection Service's regulatory programs, we developed a point-of-processing foodborne illness attribution model by adapting the Hald Salmonella Bayesian source attribution model. Key model outputs include estimates of the relative proportions of domestically acquired sporadic human Salmonella infections resulting from contamination of raw meat, poultry, and egg products processed in the United States from 1998 through 2003. The current model estimates the relative contribution of chicken (48%), ground beef (28%), turkey (17%), egg products (6%), intact beef (1%), and pork (<1%) across 109 Salmonella serotypes found in food commodities at point of processing. While interpretation of the attribution estimates is constrained by data inputs, the adapted model shows promise and may serve as a basis for a common approach to attribution of human salmonellosis and food safety decision-making in more than one country.

  6. Error-Induced Learning as a Resource-Adaptive Process in Young and Elderly Individuals

    NASA Astrophysics Data System (ADS)

    Ferdinand, Nicola K.; Weiten, Anja; Mecklinger, Axel; Kray, Jutta

    Thorndike described in his law of effect [44] that actions followed by positive events are more likely to be repeated in the future, whereas actions that are followed by negative outcomes are less likely to be repeated. This implies that behavior is evaluated in the light of its potential consequences, and non-reward events (i.e., errors) must be detected for reinforcement learning to take place. In short, humans have to monitor their performance in order to detect and correct errors, and this allows them to successfully adapt their behavior to changing environmental demands and acquire new behavior, i.e., to learn.

  7. Adaptive multispectral image processing for the detection of targets in terrain clutter

    NASA Astrophysics Data System (ADS)

    Hoff, Lawrence E.; Zeidler, James R.; Yerkes, Christopher R.

    1992-08-01

    In passive detection of small infrared targets in image data, we are faced with the difficult task of enhancing some characteristic of the target or signal while suppressing the clutter or background image noise. We reported that an effective means by which targets may be identified is to exploit characteristics which exist between scenes measured in different bands in the long wave infrared region of the electromagnetic spectrum. These methods are broadly termed multispectral techniques. In this paper we present a method by which a two- dimensional least-mean square adaptive filter is used to distinguish between target and clutter using multispectral techniques.

  8. Software Technology for Adaptable, Reliable Systems (STARS) Program. The Cleanroom Engineering Software Development Process

    DTIC Science & Technology

    1991-02-28

    required for performing a Cleanroom Engineering effort from the standpoint of specifiers, developers, certifiers, and managers . The manual was developed...Process, Process Management , Defined Process, Cleanroom, 302 Software Engineering 16. PRICE CODE N/A 17. ’.CURIrY CLASSIFICATION 18. SECURITY...Findings 1-4 1.3 IR-70 Project Profile 1-5 1.4 Acknowledgements 1-5 2. The Cleanroom Engineering Process: The Management Basis 2.1 Why Cleanroom

  9. The evolution of concepts of vestibular peripheral information processing: toward the dynamic, adaptive, parallel processing macular model.

    PubMed

    Ross, Muriel D

    2003-09-01

    In a letter to Robert Hooke, written on 5 February, 1675, Isaac Newton wrote "If I have seen further than certain other men it is by standing upon the shoulders of giants." In his context, Newton was referring to the work of Galileo and Kepler, who preceded him. However, every field has its own giants, those men and women who went before us and, often with few tools at their disposal, uncovered the facts that enabled later researchers to advance knowledge in a particular area. This review traces the history of the evolution of views from early giants in the field of vestibular research to modern concepts of vestibular organ organization and function. Emphasis will be placed on the mammalian maculae as peripheral processors of linear accelerations acting on the head. This review shows that early, correct findings were sometimes unfortunately disregarded, impeding later investigations into the structure and function of the vestibular organs. The central themes are that the macular organs are highly complex, dynamic, adaptive, distributed parallel processors of information, and that historical references can help us to understand our own place in advancing knowledge about their complicated structure and functions.

  10. The evolution of concepts of vestibular peripheral information processing: toward the dynamic, adaptive, parallel processing macular model

    NASA Technical Reports Server (NTRS)

    Ross, Muriel D.

    2003-01-01

    In a letter to Robert Hooke, written on 5 February, 1675, Isaac Newton wrote "If I have seen further than certain other men it is by standing upon the shoulders of giants." In his context, Newton was referring to the work of Galileo and Kepler, who preceded him. However, every field has its own giants, those men and women who went before us and, often with few tools at their disposal, uncovered the facts that enabled later researchers to advance knowledge in a particular area. This review traces the history of the evolution of views from early giants in the field of vestibular research to modern concepts of vestibular organ organization and function. Emphasis will be placed on the mammalian maculae as peripheral processors of linear accelerations acting on the head. This review shows that early, correct findings were sometimes unfortunately disregarded, impeding later investigations into the structure and function of the vestibular organs. The central themes are that the macular organs are highly complex, dynamic, adaptive, distributed parallel processors of information, and that historical references can help us to understand our own place in advancing knowledge about their complicated structure and functions.

  11. Software Technology for Adaptable, Reliable System (STARS) Program. Reuse Library Process Model.

    DTIC Science & Technology

    The Process Model described in this document is part of the Guidebook requirements for the STARS Reuse Library described in Subtask IS40.3 of the S...Increment Task Proposal for STARS. The objective of a Process Model is to formally characterize the various processes that take place in the context of

  12. Integrated Business Process Adaptation towards Friction-Free Business-to-Business Collaboration

    ERIC Educational Resources Information Center

    Shan, Zhe

    2011-01-01

    One key issue in process-aware E-commerce collaboration is the orchestration of business processes of multiple business partners throughout a supply chain network in an automated and seamless way. Since each partner has its own internal processes with different control flow structures and message interfaces, the real challenge lies in verifying…

  13. Adapting Environmental Education Materials.

    ERIC Educational Resources Information Center

    Peace Corps, Washington, DC. Information Collection and Exchange Div.

    This publication provides Peace Corps volunteers and others who conduct environmental education activities in schools, environmental education centers, parks, and communities with the tools to adapt existing environmental education resources to local environmental issues, cultures, and audiences. Sections include: (1) the process of adapting…

  14. The neural dynamics of somatosensory processing and adaptation across childhood: a high-density electrical mapping study

    PubMed Central

    Uppal, Neha; Foxe, John J.; Butler, John S.; Acluche, Frantzy

    2016-01-01

    Young children are often hyperreactive to somatosensory inputs hardly noticed by adults, as exemplified by irritation to seams or labels in clothing. The neurodevelopmental mechanisms underlying changes in sensory reactivity are not well understood. Based on the idea that neurodevelopmental changes in somatosensory processing and/or changes in sensory adaptation might underlie developmental differences in somatosensory reactivity, high-density electroencephalography was used to examine how the nervous system responds and adapts to repeated vibrotactile stimulation over childhood. Participants aged 6–18 yr old were presented with 50-ms vibrotactile stimuli to the right wrist over the median nerve at 5 blocked interstimulus intervals (ranging from ∼7 to ∼1 stimulus per second). Somatosensory evoked potentials (SEPs) revealed three major phases of activation within the first 200 ms, with scalp topographies suggestive of neural generators in contralateral somatosensory cortex. Although overall SEPs were highly similar for younger, middle, and older age groups (6.1–9.8, 10.0–12.9, and 13.0–17.8 yr old), there were significant age-related amplitude differences in initial and later phases of the SEP. In contrast, robust adaptation effects for fast vs. slow presentation rates were observed that did not differ as a function of age. A greater amplitude response in the later portion of the SEP was observed for the youngest group and may be related to developmental changes in responsivity to somatosensory stimuli. These data suggest the protracted development of the somatosensory system over childhood, whereas adaptation, as assayed in this study, is largely in place by ∼7 yr of age. PMID:26763781

  15. Recent Visual Experience Shapes Visual Processing in Rats through Stimulus-Specific Adaptation and Response Enhancement.

    PubMed

    Vinken, Kasper; Vogels, Rufin; Op de Beeck, Hans

    2017-03-20

    From an ecological point of view, it is generally suggested that the main goal of vision in rats and mice is navigation and (aerial) predator evasion [1-3]. The latter requires fast and accurate detection of a change in the visual environment. An outstanding question is whether there are mechanisms in the rodent visual system that would support and facilitate visual change detection. An experimental protocol frequently used to investigate change detection in humans is the oddball paradigm, in which a rare, unexpected stimulus is presented in a train of stimulus repetitions [4]. A popular "predictive coding" theory of cortical responses states that neural responses should decrease for expected sensory input and increase for unexpected input [5, 6]. Despite evidence for response suppression and enhancement in noninvasive scalp recordings in humans with this paradigm [7, 8], it has proven challenging to observe both phenomena in invasive action potential recordings in other animals [9-11]. During a visual oddball experiment, we recorded multi-unit spiking activity in rat primary visual cortex (V1) and latero-intermediate area (LI), which is a higher area of the rodent ventral visual stream. In rat V1, there was only evidence for response suppression related to stimulus-specific adaptation, and not for response enhancement. However, higher up in area LI, spiking activity showed clear surprise-based response enhancement in addition to stimulus-specific adaptation. These results show that neural responses along the rat ventral visual stream become increasingly sensitive to changes in the visual environment, suggesting a system specialized in the detection of unexpected events.

  16. Adaptive management: Chapter 1

    USGS Publications Warehouse

    Allen, Craig R.; Garmestani, Ahjond S.; Allen, Craig R.; Garmestani, Ahjond S.

    2015-01-01

    Adaptive management is an approach to natural resource management that emphasizes learning through management where knowledge is incomplete, and when, despite inherent uncertainty, managers and policymakers must act. Unlike a traditional trial and error approach, adaptive management has explicit structure, including a careful elucidation of goals, identification of alternative management objectives and hypotheses of causation, and procedures for the collection of data followed by evaluation and reiteration. The process is iterative, and serves to reduce uncertainty, build knowledge and improve management over time in a goal-oriented and structured process.

  17. Application of adaptive neuro-fuzzy inference system and cuckoo optimization algorithm for analyzing electro chemical machining process

    NASA Astrophysics Data System (ADS)

    Teimouri, Reza; Sohrabpoor, Hamed

    2013-12-01

    Electrochemical machining process (ECM) is increasing its importance due to some of the specific advantages which can be exploited during machining operation. The process offers several special privileges such as higher machining rate, better accuracy and control, and wider range of materials that can be machined. Contribution of too many predominate parameters in the process, makes its prediction and selection of optimal values really complex, especially while the process is programmized for machining of hard materials. In the present work in order to investigate effects of electrolyte concentration, electrolyte flow rate, applied voltage and feed rate on material removal rate (MRR) and surface roughness (SR) the adaptive neuro-fuzzy inference systems (ANFIS) have been used for creation predictive models based on experimental observations. Then the ANFIS 3D surfaces have been plotted for analyzing effects of process parameters on MRR and SR. Finally, the cuckoo optimization algorithm (COA) was used for selection solutions in which the process reaches maximum material removal rate and minimum surface roughness simultaneously. Results indicated that the ANFIS technique has superiority in modeling of MRR and SR with high prediction accuracy. Also, results obtained while applying of COA have been compared with those derived from confirmatory experiments which validate the applicability and suitability of the proposed techniques in enhancing the performance of ECM process.

  18. Adaptation to random and systematic errors: Comparison of amputee and non-amputee control interfaces with varying levels of process noise

    PubMed Central

    Kording, Konrad P.; Hargrove, Levi J.; Sensinger, Jonathon W.

    2017-01-01

    The objective of this study was to understand how people adapt to errors when using a myoelectric control interface. We compared adaptation across 1) non-amputee subjects using joint angle, joint torque, and myoelectric control interfaces, and 2) amputee subjects using myoelectric control interfaces with residual and intact limbs (five total control interface conditions). We measured trial-by-trial adaptation to self-generated errors and random perturbations during a virtual, single degree-of-freedom task with two levels of feedback uncertainty, and evaluated adaptation by fitting a hierarchical Kalman filter model. We have two main results. First, adaptation to random perturbations was similar across all control interfaces, whereas adaptation to self-generated errors differed. These patterns matched predictions of our model, which was fit to each control interface by changing the process noise parameter that represented system variability. Second, in amputee subjects, we found similar adaptation rates and error levels between residual and intact limbs. These results link prosthesis control to broader areas of motor learning and adaptation and provide a useful model of adaptation with myoelectric control. The model of adaptation will help us understand and solve prosthesis control challenges, such as providing additional sensory feedback. PMID:28301512

  19. Model based adaptive control of a continuous capture process for monoclonal antibodies production.

    PubMed

    Steinebach, Fabian; Angarita, Monica; Karst, Daniel J; Müller-Späth, Thomas; Morbidelli, Massimo

    2016-04-29

    A two-column capture process for continuous processing of cell-culture supernatant is presented. Similar to other multicolumn processes, this process uses sequential countercurrent loading of the target compound in order maximize resin utilization and productivity for a given product yield. The process was designed using a novel mechanistic model for affinity capture, which takes both specific adsorption as well as transport through the resin beads into account. Simulations as well as experimental results for the capture of an IgG antibody are discussed. The model was able to predict the process performance in terms of yield, productivity and capacity utilization. Compared to continuous capture with two columns operated batch wise in parallel, a 2.5-fold higher capacity utilization was obtained for the same productivity and yield. This results in an equal improvement in product concentration and reduction of buffer consumption. The developed model was used not only for the process design and optimization but also for its online control. In particular, the unit operating conditions are changed in order to maintain high product yield while optimizing the process performance in terms of capacity utilization and buffer consumption also in the presence of changing upstream conditions and resin aging.

  20. Adaptive Image Processing Methods for Improving Contaminant Detection Accuracy on Poultry Carcasses

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Technical Abstract A real-time multispectral imaging system has demonstrated a science-based tool for fecal and ingesta contaminant detection during poultry processing. In order to implement this imaging system at commercial poultry processing industry, the false positives must be removed. For doi...

  1. Adaptive Memory: Survival Processing Increases Both True and False Memory in Adults and Children

    ERIC Educational Resources Information Center

    Otgaar, Henry; Smeets, Tom

    2010-01-01

    Research has shown that processing information in a survival context can enhance the information's memorability. The current study examined whether survival processing can also decrease the susceptibility to false memories and whether the survival advantage can be found in children. In Experiment 1, adults rated semantically related words in a…

  2. Adaptive Process Controls and Ultrasonics for High Temperature PEM MEA Manufacture

    SciTech Connect

    Walczyk, Daniel F.

    2015-08-26

    The purpose of this 5-year DOE-sponsored project was to address major process bottlenecks associated with fuel cell manufacturing. New technologies were developed to significantly reduce pressing cycle time for high temperature PEM membrane electrode assembly (MEA) through the use of novel, robust ultrasonic (U/S) bonding processes along with low temperature (<100°C) PEM MEAs. In addition, greater manufacturing uniformity and performance was achieved through (a) an investigation into the causes of excessive variation in ultrasonically and thermally bonded MEAs using more diagnostics applied during the entire fabrication and cell build process, and (b) development of rapid, yet simple quality control measurement techniques for use by industry.

  3. Intestinal adaptation following resection.

    PubMed

    Tappenden, Kelly A

    2014-05-01

    Intestinal adaptation is a natural compensatory process that occurs following extensive intestinal resection, whereby structural and functional changes in the intestine improve nutrient and fluid absorption in the remnant bowel. In animal studies, postresection structural adaptations include bowel lengthening and thickening and increases in villus height and crypt depth. Functional changes include increased nutrient transporter expression, accelerated crypt cell differentiation, and slowed transit time. In adult humans, data regarding adaptive changes are sparse, and the mechanisms underlying intestinal adaptation remain to be fully elucidated. Several factors influence the degree of intestinal adaptation that occurs post resection, including site and extent of resection, luminal stimulation with enteral nutrients, and intestinotrophic factors. Two intestinotrophic growth factors, the glucagon-like peptide 2 analog teduglutide and recombinant growth hormone (somatropin), are now approved for clinical use in patients with short bowel syndrome (SBS). Both agents enhance fluid absorption and decrease requirements for parenteral nutrition (PN) and/or intravenous fluid. Intestinal adaptation has been thought to be limited to the first 1-2 years following resection in humans. However, recent data suggest that a significant proportion of adult patients with SBS can achieve enteral autonomy, even after many years of PN dependence, particularly with trophic stimulation.

  4. To adopt is to adapt: the process of implementing the ICF with an acute stroke multidisciplinary team in England

    PubMed Central

    Tempest, Stephanie; Harries, Priscilla; Kilbride, Cherry; De Souza, Lorraine

    2012-01-01

    Purpose: The success of the International Classifcation of Functioning, Disability and Health (ICF) depends on its uptake in clinical practice. This project aimed to explore ways the ICF could be used with an acute stroke multidisciplinary team and identify key learning from the implementation process. Method: Using an action research approach, iterative cycles of observe, plan, act and evaluate were used within three phases: exploratory; innovatory and refective. Thematic analysis was undertaken, using a model of immersion and crystallisation, on data collected via interview and focus groups, e-mail communications, minutes from relevant meetings, feld notes and a refective diary. Results: Two overall themes were determined from the data analysis which enabled implementation. There is a need to: (1) adopt the ICF in ways that meet local service needs; and (2) adapt the ICF language and format. Conclusions: The empirical fndings demonstrate how to make the ICF classifcation a clinical reality. First, we need to adopt the ICF as a vehicle to implement local service priorities e.g. to structure a multidisciplinary team report, thus enabling ownership of the implementation process. Second, we need to adapt the ICF terminology and format to make it acceptable for use by clinicians. PMID:22372376

  5. Predominant processing adaptability of Staphylococcus xylosus strains isolated from Chinese traditional low-salt fermented whole fish.

    PubMed

    Zeng, Xuefeng; He, Laping; Guo, Xu; Deng, Li; Yang, Wangen; Zhu, Qiujin; Duan, Zhenhua

    2017-02-02

    This study aimed to determine the predominant processing adaptability of 27 selected isolates of Staphylococcus xylosus in 'Suan yu', a traditional Chinese low-salt fermented whole-fish product. The isolates were screened for proteolytic, lipolytic, and enzymatic profiles; amino-acid decarboxylase content; antimicrobial activities; and tolerance to low temperatures, pH5.0, and salt. Two S. xylosus strains grew at 10°C in the presence of 10% NaCl and at pH5.0. Agar-plate assays and sodium dodecyl sulphate-polyacrylamide gel electrophoresis revealed that 21 and 8 of the strains exhibited appropriate proteolytic activities against myofibrillar and sarcoplasmic proteins, respectively. All S. xylosus strains also displayed different enzymatic profiles, and most strains showed negative decarboxylase activities. The results of this step were used as input data for a Principal Component Analysis; therefore, the most technologically relevant strain 3 and 8 were combined with L. plantarum 120 as MS1 and MS2, respectively, were further selected for the fermented fish surimi, and the fish surimi inoculated with mixed starter cultures (MS1, MS2) scored high for overall acceptability. Free amino acid contents of 1757 and 1765mg/100g sample were found in fish surimi inoculated with MS1 and MS2, respectively, after 72h of fermentation. Therefore, Sx-3 and Sx-8, which presented the best predominant processing adaptability, is an eligible starter culture for fermented fish production.

  6. Adaptive and robust statistical methods for processing near-field scanning microwave microscopy images.

    PubMed

    Coakley, K J; Imtiaz, A; Wallis, T M; Weber, J C; Berweger, S; Kabos, P

    2015-03-01

    Near-field scanning microwave microscopy offers great potential to facilitate characterization, development and modeling of materials. By acquiring microwave images at multiple frequencies and amplitudes (along with the other modalities) one can study material and device physics at different lateral and depth scales. Images are typically noisy and contaminated by artifacts that can vary from scan line to scan line and planar-like trends due to sample tilt errors. Here, we level images based on an estimate of a smooth 2-d trend determined with a robust implementation of a local regression method. In this robust approach, features and outliers which are not due to the trend are automatically downweighted. We denoise images with the Adaptive Weights Smoothing method. This method smooths out additive noise while preserving edge-like features in images. We demonstrate the feasibility of our methods on topography images and microwave |S11| images. For one challenging test case, we demonstrate that our method outperforms alternative methods from the scanning probe microscopy data analysis software package Gwyddion. Our methods should be useful for massive image data sets where manual selection of landmarks or image subsets by a user is impractical.

  7. Delivering culturally sensitive health messages: the process of adapting brochures for grandparents raising grandchildren in Hawai'i.

    PubMed

    Yancura, Loriena A

    2010-05-01

    The efficacy of programs to reduce health disparities depends on their ability to deliver messages in a culturally sensitive manner. This article describes the process of designing a series of brochures for grandparents raising grandchildren. National source material on topics important to grandparents (self-care, service use, addiction, and grandchildren's difficult behaviors) was put into draft brochures and pilot tested in two focus groups drawn from Native Hawaiian Asian and Pacific Islander populations. Elements of surface and deep levels directed the form and content of the final brochures. On a surface level, these brochures reflect local culture through pictures and language. On a deep level, which integrates cultural beliefs and practices, they reflect the importance of indirect communication and harmonious relationships. The final brochures have been received favorably in the community. The process of adapting educational material with attention to surface and deep levels can serve as a guide for other health promotion materials.

  8. Adapting Nielsen’s Design Heuristics to Dual Processing for Clinical Decision Support

    PubMed Central

    Taft, Teresa; Staes, Catherine; Slager, Stacey; Weir, Charlene

    2016-01-01

    The study objective was to improve the applicability of Nielson’s standard design heuristics for evaluating electronic health record (EHR) alerts and linked ordering support by integrating them with Dual Process theory. Through initial heuristic evaluation and a user study of 7 physicians, usability problems were identified. Through independent mapping of specific usability criteria to support for each of the Dual Cognitive processes (S1 and S2) and deliberation, agreement was reached on mapping criteria. Finally, usability errors from the heuristic and user study were mapped to S1 and S2. Adding a dual process perspective to specific heuristic analysis increases the applicability and relevance of computerized health information design evaluations. This mapping enables designers to measure that their systems are tailored to support attention allocation. System 1 will be supported by improving pattern recognition and saliency, and system 2 through efficiency and control of information access. PMID:28269915

  9. Adaptive tracking of weld joints using active contour model in arc-welding processes

    NASA Astrophysics Data System (ADS)

    Kim, Jaeseon; Koh, Kyoungchul; Cho, Hyungsuck

    2001-02-01

    12 This paper presents a vision processing scheme to automatic weld joint tracking in robotic arc welding process. Particular attention is concentrated on its robustness against various optical disturbances, such as arc glares and weld spatters radiating from the melted weld pool. Underlying the developed vision processing is a kind of model-based pattern searching, which is necessarily accompanied by two separate stages of modeling and tracking. In the modeling stage, a syntactic approach is adopted to identify unknown weld joint structure. The joint profile identified in the modeling stage is used as a starting point for successive tracking of variations in the geometry of weld joint during welding, which is automatically achieved by an active contour model technology following feature- based template matching. The performance of the developed scheme is investigated through a series of practical welding experiments.

  10. Visual Impairment, Including Blindness

    MedlinePlus

    ... net/ Back to top Adapting the Environment Making adaptations to the environment where a child with a ... or school personnel to decide what kinds of adaptations are necessary to ensure the child’s safety while ...

  11. Carbon and arsenic metabolism in Thiomonas strains: differences revealed diverse adaptation processes

    PubMed Central

    2009-01-01

    Background Thiomonas strains are ubiquitous in arsenic-contaminated environments. Differences between Thiomonas strains in the way they have adapted and respond to arsenic have never been studied in detail. For this purpose, five Thiomonas strains, that are interesting in terms of arsenic metabolism were selected: T. arsenivorans, Thiomonas spp. WJ68 and 3As are able to oxidise As(III), while Thiomonas sp. Ynys1 and T. perometabolis are not. Moreover, T. arsenivorans and 3As present interesting physiological traits, in particular that these strains are able to use As(III) as an electron donor. Results The metabolism of carbon and arsenic was compared in the five Thiomonas strains belonging to two distinct phylogenetic groups. Greater physiological differences were found between these strains than might have been suggested by 16S rRNA/rpoA gene phylogeny, especially regarding arsenic metabolism. Physiologically, T. perometabolis and Ynys1 were unable to oxidise As(III) and were less arsenic-resistant than the other strains. Genetically, they appeared to lack the aox arsenic-oxidising genes and carried only a single ars arsenic resistance operon. Thiomonas arsenivorans belonged to a distinct phylogenetic group and increased its autotrophic metabolism when arsenic concentration increased. Differential proteomic analysis revealed that in T. arsenivorans, the rbc/cbb genes involved in the assimilation of inorganic carbon were induced in the presence of arsenic, whereas these genes were repressed in Thiomonas sp. 3As. Conclusion Taken together, these results show that these closely related bacteria differ substantially in their response to arsenic, amongst other factors, and suggest different relationships between carbon assimilation and arsenic metabolism. PMID:19549320

  12. Intestinal mucosal atrophy and adaptation.

    PubMed

    Shaw, Darcy; Gohil, Kartik; Basson, Marc D

    2012-11-28

    Mucosal adaptation is an essential process in gut homeostasis. The intestinal mucosa adapts to a range of pathological conditions including starvation, short-gut syndrome, obesity, and bariatric surgery. Broadly, these adaptive functions can be grouped into proliferation and differentiation. These are influenced by diverse interactions with hormonal, immune, dietary, nervous, and mechanical stimuli. It seems likely that clinical outcomes can be improved by manipulating the physiology of adaptation. This review will summarize current understanding of the basic science surrounding adaptation, delineate the wide range of potential targets for therapeutic intervention, and discuss how these might be incorporated into an overall treatment plan. Deeper insight into the physiologic basis of adaptation will identify further targets for intervention to improve clinical outcomes.

  13. Intestinal mucosal atrophy and adaptation

    PubMed Central

    Shaw, Darcy; Gohil, Kartik; Basson, Marc D

    2012-01-01

    Mucosal adaptation is an essential process in gut homeostasis. The intestinal mucosa adapts to a range of pathological conditions including starvation, short-gut syndrome, obesity, and bariatric surgery. Broadly, these adaptive functions can be grouped into proliferation and differentiation. These are influenced by diverse interactions with hormonal, immune, dietary, nervous, and mechanical stimuli. It seems likely that clinical outcomes can be improved by manipulating the physiology of adaptation. This review will summarize current understanding of the basic science surrounding adaptation, delineate the wide range of potential targets for therapeutic intervention, and discuss how these might be incorporated into an overall treatment plan. Deeper insight into the physiologic basis of adaptation will identify further targets for intervention to improve clinical outcomes. PMID:23197881

  14. Seeing the Light: Adapting Luminance Reveals Low-Level Visual Processes in the Attentional Blink

    ERIC Educational Resources Information Center

    Giesbrecht, Barry; Bischof, Walter F.; Kingstone, Alan

    2004-01-01

    It is widely assumed that high-level visual processes subserve the attentional blink (AB). Recent evidence from studies of visual masking during the AB that were designed to directly test the contributions of high-level masking effects, however, have failed to provide empirical support for this position.The implication is that low-level visual…

  15. Learning Effects of a Science Textbook Designed with Adapted Cognitive Process Principles on Grade 5 Students

    ERIC Educational Resources Information Center

    Cheng, Ming-Chang; Chou, Pei-I; Wang, Ya-Ting; Lin, Chih-Ho

    2015-01-01

    This study investigates how the illustrations in a science textbook, with their design modified according to cognitive process principles, affected students' learning performance. The quasi-experimental design recruited two Grade 5 groups (N?=?58) as the research participants. The treatment group (n?=?30) used the modified version of the textbook,…

  16. Adapting the Interpersonal Process Model of Intimacy to Enhance the Co-Leader Relationship during Training

    ERIC Educational Resources Information Center

    Huffman, David D.; Fernando, Delini M.

    2012-01-01

    Group work literature acknowledges that the group co-leader relationship influences the development of group members and the group as a whole. However, little direction has been offered for supervisors of group co-leaders to facilitate the development of the co-leader relationship. Reis and Shaver's (1988) interpersonal process model of intimacy…

  17. [Mechanisms of psychological adaptation of anesthesiologists-resuscitators to the stress-induced conditions of professional occupation and possibilities of their correction within a teaching process].

    PubMed

    Shchelkova, O Iu; Mazurok, V A

    2007-01-01

    High psychological tension results in the development of specific coping behavior. Ninety-six anesthesiologists, including 62 (64.6%) males and 34 (35.4%) females, were examined to reveal the mechanisms of psychological adaptation to stress-induced conditions of professional occupation. The respondents were ascertained to most frequently use cognitive, emotional, and behavioral constructive copings in settling stress situations. Nonadaptive copings most commonly contemplate a refusal to get over difficulties due to the lack of faith in power, to the underestimation of the importance of negative events, to passivity, isolation, etc., which is traditionally considered to be a manifestation of the emotional burnout syndrome in attendants. Psychological training within a teaching process may be regarded as a help to physicians in developing constructive coping strategies, training in self-diagnosis and self-help in the early manifestations of emotional burnout.

  18. Synthetic physiology strategies for adapting tools from nature for genetically targeted control of fast biological processes.

    PubMed

    Chow, Brian Y; Chuong, Amy S; Klapoetke, Nathan C; Boyden, Edward S

    2011-01-01

    The life and operation of cells involve many physiological processes that take place over fast timescales of milliseconds to minutes. Genetically encoded technologies for driving or suppressing specific fast physiological processes in intact cells, perhaps embedded within intact tissues in living organisms, are critical for the ability to understand how these physiological processes contribute to emergent cellular and organismal functions and behaviors. Such "synthetic physiology" tools are often incredibly complex molecular machines, in part because they must operate at high speeds, without causing side effects. We here explore how synthetic physiology molecules can be identified and deployed in cells, and how the physiology of these molecules in cellular contexts can be assessed and optimized. For concreteness, we discuss these methods in the context of the "optogenetic" light-gated ion channels and pumps that we have developed over the past few years as synthetic physiology tools and widely disseminated for use in neuroscience for probing the role of specific brain cell types in neural computations, behaviors, and pathologies. We anticipate that some of the insights revealed here may be of general value for the field of synthetic physiology, as they raise issues that will be of importance for the development and use of high-performance, high-speed, side-effect free physiological control tools in heterologous expression systems.

  19. “Vulnerability, Resiliency, and Adaptation: The Health of Latin Americans during the Migration Process to the United States”*

    PubMed Central

    Riosmena, Fernando; Jochem, Warren C.

    2013-01-01

    In this paper, we offer a general outlook of the health of Latin Americans (with a special emphasis on Mexicans) during the different stages of the migration process to the U.S. given the usefulness of the social vulnerability concept and given that said vulnerability varies conspicuously across the different stages of the migration process. Severe migrant vulnerability during the transit and crossing has serious negative health consequences. Yet, upon their arrival to the U.S., migrant health is favorable in outcomes such as mortality by many causes of death and in several chronic conditions and risk factors, though these apparent advantages seem to disappear during the process of adaptation to the host society. We discuss potential explanations for the initial health advantage and the sources of vulnerability that explain its erosion, with special emphasis in systematic timely access to health care. Given that migration can affect social vulnerability processes in sending areas, we discuss the potential health consequences for these places and conclude by considering the immigration and health policy implications of these issues for the United States and sending countries, with emphasis on Mexico. PMID:24660053

  20. Collective Signal Processing in Cluster Chemotaxis: Roles of Adaptation, Amplification, and Co-attraction in Collective Guidance

    PubMed Central

    Camley, Brian A.; Zimmermann, Juliane; Levine, Herbert; Rappel, Wouter-Jan

    2016-01-01

    Single eukaryotic cells commonly sense and follow chemical gradients, performing chemotaxis. Recent experiments and theories, however, show that even when single cells do not chemotax, clusters of cells may, if their interactions are regulated by the chemoattractant. We study this general mechanism of “collective guidance” computationally with models that integrate stochastic dynamics for individual cells with biochemical reactions within the cells, and diffusion of chemical signals between the cells. We show that if clusters of cells use the well-known local excitation, global inhibition (LEGI) mechanism to sense chemoattractant gradients, the speed of the cell cluster becomes non-monotonic in the cluster’s size—clusters either larger or smaller than an optimal size will have lower speed. We argue that the cell cluster speed is a crucial readout of how the cluster processes chemotactic signals; both amplification and adaptation will alter the behavior of cluster speed as a function of size. We also show that, contrary to the assumptions of earlier theories, collective guidance does not require persistent cell-cell contacts and strong short range adhesion. If cell-cell adhesion is absent, and the cluster cohesion is instead provided by a co-attraction mechanism, e.g. chemotaxis toward a secreted molecule, collective guidance may still function. However, new behaviors, such as cluster rotation, may also appear in this case. Co-attraction and adaptation allow for collective guidance that is robust to varying chemoattractant concentrations while not requiring strong cell-cell adhesion. PMID:27367541

  1. Cognitive flexibility in adolescence: neural and behavioral mechanisms of reward prediction error processing in adaptive decision making during development.

    PubMed

    Hauser, Tobias U; Iannaccone, Reto; Walitza, Susanne; Brandeis, Daniel; Brem, Silvia

    2015-01-01

    Adolescence is associated with quickly changing environmental demands which require excellent adaptive skills and high cognitive flexibility. Feedback-guided adaptive learning and cognitive flexibility are driven by reward prediction error (RPE) signals, which indicate the accuracy of expectations and can be estimated using computational models. Despite the importance of cognitive flexibility during adolescence, only little is known about how RPE processing in cognitive flexibility deviates between adolescence and adulthood. In this study, we investigated the developmental aspects of cognitive flexibility by means of computational models and functional magnetic resonance imaging (fMRI). We compared the neural and behavioral correlates of cognitive flexibility in healthy adolescents (12-16years) to adults performing a probabilistic reversal learning task. Using a modified risk-sensitive reinforcement learning model, we found that adolescents learned faster from negative RPEs than adults. The fMRI analysis revealed that within the RPE network, the adolescents had a significantly altered RPE-response in the anterior insula. This effect seemed to be mainly driven by increased responses to negative prediction errors. In summary, our findings indicate that decision making in adolescence goes beyond merely increased reward-seeking behavior and provides a developmental perspective to the behavioral and neural mechanisms underlying cognitive flexibility in the context of reinforcement learning.

  2. Information processing in the adaptation of Saccharomyces cerevisiae to osmotic stress: an analysis of the phosphorelay system.

    PubMed

    Uschner, Friedemann; Klipp, Edda

    2014-12-01

    Cellular signaling is key for organisms to survive immediate stresses from fluctuating environments as well as relaying important information about external stimuli. Effective mechanisms have evolved to ensure appropriate responses for an optimal adaptation process. For them to be functional despite the noise that occurs in biochemical transmission, the cell needs to be able to infer reliably what was sensed in the first place. For example Saccharomyces cerevisiae are able to adjust their response to osmotic shock depending on the severity of the shock and initiate responses that lead to near perfect adaptation of the cell. We investigate the Sln1-Ypd1-Ssk1-phosphorelay as a module in the high-osmolarity glycerol pathway by incorporating a stochastic model. Within this framework, we can imitate the noisy perception of the cell and interpret the phosphorelay as an information transmitting channel in the sense of C.E. Shannon's "Information Theory". We refer to the channel capacity as a measure to quantify and investigate the transmission properties of this system, enabling us to draw conclusions on viable parameter sets for modeling the system.

  3. Modified reconstruction algorithm based on space-time adaptive processing for multichannel synthetic aperture radar systems in azimuth

    NASA Astrophysics Data System (ADS)

    Guo, Xiaojiang; Gao, Yesheng; Wang, Kaizhi; Liu, Xingzhao

    2016-07-01

    A spectrum reconstruction algorithm based on space-time adaptive processing (STAP) can effectively suppress azimuth ambiguity for multichannel synthetic aperture radar (SAR) systems in azimuth. However, the traditional STAP-based reconstruction approach has to estimate the covariance matrix and calculate matrix inversion (MI) for each Doppler frequency bin, which will result in a very large computational load. In addition, the traditional STAP-based approach has to know the exact platform velocity, pulse repetition frequency, and array configuration. Errors involving these parameters will significantly degrade the performance of ambiguity suppression. A modified STAP-based approach to solve these problems is presented. The traditional array steering vectors and corresponding covariance matrices are Doppler-variant in the range-Doppler domain. After preprocessing by a proposed phase compensation method, they would be independent of Doppler bins. Therefore, the modified STAP-based approach needs to estimate the covariance matrix and calculate MI only once. The computation load could be greatly reduced. Moreover, by combining the reconstruction method and a proposed adaptive parameter estimation method, the modified method is able to successfully achieve multichannel SAR signal reconstruction and suppress azimuth ambiguity without knowing the above parameters. Theoretical analysis and experiments showed the simplicity and efficiency of the proposed methods.

  4. Investigation of adaptive signal processing methods for denoised I-V curve of Langmuir probe

    NASA Astrophysics Data System (ADS)

    Lee, Jung Yeol; Han, Moon-Ki; Lee, Ho-Jun; Lee, Hae June

    2016-09-01

    It is an important issue to obtain a clear second derivative of Langmuir probe I-V curve which involves the electron energy distribution function. Therefore, noise suppressions against random walk of charges are required in the experimental data. Proper numerical methods including fitting, digital smoothing, digital filtering with window function should be used to remove each types of noise to determine electron energy distribution. The calculation of electron energy distributions demands sequential algorithm of several numerical methods to reduce the noise in I-V curve. In this presentation, a new noise suppression method is suggested to achieve advanced Langmuir probe diagnostics. Combined utilization of nonlinear curve fitting and low pass filter with window function shows more precise results than the utilization of smoothing only. Therefore, results including noise analysis algorithm give new guideline of probe diagnostics.

  5. ERP evidence of adaptive changes in error processing and attentional control during rhythm synchronization learning.

    PubMed

    Padrão, Gonçalo; Penhune, Virginia; de Diego-Balaguer, Ruth; Marco-Pallares, Josep; Rodriguez-Fornells, Antoni

    2014-10-15

    The ability to detect and use information from errors is essential during the acquisition of new skills. There is now a wealth of evidence about the brain mechanisms involved in error processing. However, the extent to which those mechanisms are engaged during the acquisition of new motor skills remains elusive. Here we examined rhythm synchronization learning across 12 blocks of practice in musically naïve individuals and tracked changes in ERP signals associated with error-monitoring and error-awareness across distinct learning stages. Synchronization performance improved with practice, and performance improvements were accompanied by dynamic changes in ERP components related to error-monitoring and error-awareness. Early in learning, when performance was poor and the internal representations of the rhythms were weaker we observed a larger error-related negativity (ERN) following errors compared to later learning. The larger ERN during early learning likely results from greater conflict between competing motor responses, leading to greater engagement of medial-frontal conflict monitoring processes and attentional control. Later in learning, when performance had improved, we observed a smaller ERN accompanied by an enhancement of a centroparietal positive component resembling the P3. This centroparietal positive component was predictive of participant's performance accuracy, suggesting a relation between error saliency, error awareness and the consolidation of internal templates of the practiced rhythms. Moreover, we showed that during rhythm learning errors led to larger auditory evoked responses related to attention orientation which were triggered automatically and which were independent of the learning stage. The present study provides crucial new information about how the electrophysiological signatures related to error-monitoring and error-awareness change during the acquisition of new skills, extending previous work on error processing and cognitive

  6. Laser Encapsulation of Organic Electronics with Adapted Diode Lasers in Flexible Production Processes

    NASA Astrophysics Data System (ADS)

    Brosda, Maximilian; Olowinsky, Alexander; Pelzer, Alexander

    Flexible organic electronics such as OLPV and OLED modules are highly sensitive against water and oxygen. To protect them against the environment and to ensure a long lifetime visual transparent ultra high barrier films are used for the encapsulation process. These multilayer films usually consist of a polymer substrate on which, depending on the requirements, various functional layers are applied. The organic device is then fully packed in this films. Instead of conventional joining these film with adhesive, a flexible laser based process can be an interesting alternative especially for roll2roll applications. According to a precise spectral analysis and a consideration of the interaction between the laser radiation and the individual layers of the film a suitable laser beam source is selected. With this laser beam source the weldability of the films is investigated. For analysis of the weldseam and the melted volume cross sections and scanning-electron-microscopy-images are prepared. The strength of the weld is determined by T-Peel tensile tests.

  7. Effect of chemicals, heat, and histopathologic processing on high-infectivity hamster-adapted scrapie virus.

    PubMed

    Brown, P; Rohwer, R G; Green, E M; Gajdusek, D C

    1982-05-01

    High-titered (greater than 10(10) LD50 [50% lethal dose[/g) preparations of scrapie virus-infected hamster brain were subjected to inactivation by various chemicals, autoclaving, and histopathologic processing. Sodium hypochlorite, which reduced infectivity by approximately 4 log LD50/g of brain (99.99%), was somewhat superior to sodium metaperiodate and clearly superior to chlorine dioxide, Lysol (National Laboratories, Montvale, N.J.), iodine, potassium permanganate, and hydrogen peroxide. Most inactivation occurred within 15-30 min of exposure to a chemical, and little if any additional inactivation occurred after 1 hr. Brains processed for histopathologic examination (formalin fixation followed by dehydration in methanol, clearing in chloroform, and embedding in paraffin) retained greater than or equal to 6.8 log LD50/g of the infectivity present in unprocessed control tissues (9.6 log LD50/g). One hour in an autoclave at 121 C reduced the titer of scrapie virus by approximately 7.5 log LD50/g of brain but left 2.5 log LD50/g of residual infectivity. A combination of exposure to chemicals and autoclaving may be necessary to sterilize high-titered scrapie virus-infected tissue.

  8. Adaptation of a Control Center Development Environment for Industrial Process Control

    NASA Technical Reports Server (NTRS)

    Killough, Ronnie L.; Malik, James M.

    1994-01-01

    In the control center, raw telemetry data is received for storage, display, and analysis. This raw data must be combined and manipulated in various ways by mathematical computations to facilitate analysis, provide diversified fault detection mechanisms, and enhance display readability. A development tool called the Graphical Computation Builder (GCB) has been implemented which provides flight controllers with the capability to implement computations for use in the control center. The GCB provides a language that contains both general programming constructs and language elements specifically tailored for the control center environment. The GCB concept allows staff who are not skilled in computer programming to author and maintain computer programs. The GCB user is isolated from the details of external subsystem interfaces and has access to high-level functions such as matrix operators, trigonometric functions, and unit conversion macros. The GCB provides a high level of feedback during computation development that improves upon the often cryptic errors produced by computer language compilers. An equivalent need can be identified in the industrial data acquisition and process control domain: that of an integrated graphical development tool tailored to the application to hide the operating system, computer language, and data acquisition interface details. The GCB features a modular design which makes it suitable for technology transfer without significant rework. Control center-specific language elements can be replaced by elements specific to industrial process control.

  9. Hydrology and hydraulics expertise in participatory processes for climate change adaptation in the Dutch Meuse.

    PubMed

    Wesselink, Anna; de Vriend, Huib; Barneveld, Hermjan; Krol, Maarten; Bijker, Wiebe

    2009-01-01

    Many scientists feel that scientific outcomes are not sufficiently taken into account in policy-making. The research reported in this paper shows what happens with scientific information during such a process. In 2001 the Dutch Ministry of Transport, Public Works and Water Management commissioned their regional office in Limburg to assess how flood management objectives could be achieved in future in the Dutch Meuse valley, assuming climate change will increase peak discharges. To ensure political support, regional discussion rounds were to help assess the measures previously identified. This paper discusses the ways in which hydrological and hydraulic expertise was input, understood and used in this assessment process. Project participants as a group had no trouble contesting assumptions and outcomes. Nevertheless, water expertise was generally accepted as providing facts, once basic choices such as starting situation had been discussed and agreed. The technical constraints determined that politically unacceptable measures would have to be selected to achieve the legally binding flood management objective. As a result, no additional space will be set aside for future flood management beyond the already reserved floodplain. In this case, political arguments clearly prevail over policy objectives, with hydraulic expertise providing decisive arbitration between the two.

  10. Morphological adaptation of the calamistrum to the cribellate spinning process in Deinopoidae (Uloboridae, Deinopidae)

    PubMed Central

    Joel, Anna-Christin; Scholz, Ingo; Orth, Linda; Kappel, Peter; Baumgartner, Werner

    2016-01-01

    Spiders are famous for their silk with fascinating mechanical properties. However, some can further produce, process and handle nano fibres, which are used as capture threads. These ‘cribellate spiders’ bear a specialized setae comb on their metatarsus (calamistrum), which modifies cribellate nano fibres to assemble a puffy structure within the capture thread. Among different species, the calamistrum morphology can differ remarkably. Although a model of thread production has been established for Uloborus plumipes, it is not resolved if/how different shaped calamistra influence the production process. We were able to transfer the model without restrictions to spiders with different shaped calamistra. Fibres are not locked between setae but are passing across a rather smooth surface-like area on the calamistrum. This area can be relocated, explaining the first morphological difference between calamistra, without changing the influence of the calamistrum on fibres. By performing an elongated leg movement, contact between fibres and calamistrum could be adjusted after finishing thread production. This movement has to bring the thread in contact with the second morphological peculiarity: cribellate teeth. We suggest these teeth are used to handle the thread independently of the spinnerets, a feature only necessary for spiders, which do not move during web construction. PMID:26998332

  11. [Selective processes and adaptive evolution of the cytochrome b gene in salamanders of the genus Salamandrella].

    PubMed

    Maliarchuk, B A

    2012-06-01

    Sequence analysis of the cytochrome b gene fragment in the salamanders of the genus Salamandrella, Siberian salamander and Schrenk salamander was performed with the purpose to elucidate the effect of natural selection on the evolution of mitochondrial DNA (mtDNA) in these species. It was demonstrated that despite of notable influence of negative selection (expressed as very low dN/dS values), speciation and intraspecific divergence in salamanders was accompanied by the appearance of radical amino acid substitutions, caused by the influence of positive (directional) selection. To examine the evolutionary pattern of synonymous mtDNA sites, distribution of conservative and non-conservative substitutions was analyzed. The rates of conservative and non-conservative substitutions were nearly equal, pointing to neutrality of mutation process at synonymous mtDNA sites of salamanders. Analysis of conservative and non-conservative synonymous substitution distributions in different parts of phylogenetic trees showed that the differences between the synonymous groups compared were statistically significant only in one phylogenetic group of Siberian salamander (haplogroup C) (P = 0.02). In the group of single substitutions, located at terminal phylogenetic branches of Siberian salamanders from group C, increased rate of conservative substitutions was observed. Based on these findings, it was suggested that selective processes could have an influence on the formation of the synonymous substitution profile in the Siberian salamander mtDNA fragment examined.

  12. Accelerating Best Care in Pennsylvania: adapting a large academic system's quality improvement process to rural community hospitals.

    PubMed

    Haydar, Ziad; Gunderson, Julie; Ballard, David J; Skoufalos, Alexis; Berman, Bettina; Nash, David B

    2008-01-01

    Industrial quality improvement (QI) methods such as continuous quality improvement (CQI) may help bridge the gap between evidence-based "best care" and the quality of care provided. In 2006, Baylor Health Care System collaborated with Jefferson Medical College of Thomas Jefferson University to conduct a QI demonstration project in select Pennsylvania hospitals using CQI techniques developed by Baylor. The training was provided over a 6-month period and focused on methods for rapid-cycle improvement; data system design; data management; tools to improve patient outcomes, processes of care, and cost-effectiveness; use of clinical guidelines and protocols; leadership skills; and customer service skills. Participants successfully implemented a variety of QI projects. QI education programs developed and pioneered within large health care systems can be adapted and applied successfully to other settings, providing needed tools to smaller rural and community hospitals that lack the necessary resources to establish such programs independently.

  13. Modeling of imaging fiber bundles and adapted signal processing for fringe projection

    NASA Astrophysics Data System (ADS)

    Matthias, Steffen; Kästner, Markus; Reithmeier, Eduard

    2016-12-01

    Fringe projection profilometry is an established technique for capturing three-dimensional (3-D)-geometry data with high-point densities in short time. By combining fringe projection with endoscopy techniques, it is possible to perform inline inspection of industrial manufacturing processes. A new fringe projection system is presented, which uses flexible image fiber bundles to achieve versatile positioning of a compact sensor head. When measuring specimens with highly varying reflectivity, such as technical surfaces on tool geometries, measurement errors increase especially due to the crosstalk between individual fibers in the bundle. A detailed analysis of the transmission properties of the utilized fiber bundles is presented. It is shown that aliasing is avoided due to the non-regular grid structure of a bundle. Different techniques are demonstrated to reduce the effect of crosstalk on the phase evaluation. Measurements of highly reflective technical surfaces with different geometrical properties are shown.

  14. "Research protocol: a synthesis of qualitative studies on the process of adaptation to dependency in elderly persons and their families"

    PubMed Central

    2010-01-01

    Background Dealing with dependency in the elderly and their families leads us to explore the life experience of those involved together with the processes of adaptation to this condition. A number of original studies have been published which, following a qualitative methodology, have dealt with both dimensions. Methods/Design Objectives: 1) To present a synthesis of the qualitative evidence available on the process of adaptation to dependency in elderly persons and their families; 2) to conduct an in-depth study into the experiences and strategies developed by both to optimise their living conditions; 3) to enable standards of action/intervention to be developed in the caregiving environment. A synthesis of qualitative studies is projected with an extensive and inclusive bibliography search strategy. The primary search will focus on the major databases (CINAHL, MEDLINE, EMBASE, PsycInfo, PSICODOC, Cochrane Library, JBI, EMBASE, LILACS, CUIDEN, CUIDEN qualitative, CUIDATGE, British Nursing Index, SSCI). The secondary search will be conducted in articles taken from the references to studies identified in the articles and reports and the manual search in congresses and foundation papers. Article quality will be assessed by the guide proposed by Sandelowski & Barroso and data extraction done using the QARI data extraction form proposed by the Joanna Briggs Institute for Evidence-Based Practice. The synthesis of the findings will be based on the principles and procedures of grounded theory: coding, identification and relationship between categories, and synthesis using constant comparison as a strategy. Discussion This synthesis of qualitative evidence will enable us to detect health needs as perceived by the receivers in their own interaction contexts. PMID:20738846

  15. Perceptual decision processes flexibly adapt to avoid change-of-mind motor costs.

    PubMed

    Moher, Jeff; Song, Joo-Hyun

    2014-07-01

    The motor system is tightly linked with perception and cognition. Recent studies have shown that even anticipated biophysical action costs associated with competing response options can be incorporated into decision-making processes. As a result, choices associated with high energy costs are less likely to be selected. However, some action costs may be harder to predict. For example, a person choosing among apples at a grocery store may change his or her mind suddenly about which apple to put into the cart. This change of mind may be reflected in motor output as the initial decision triggers a motor response toward a Granny Smith that is subsequently redirected toward a Red Delicious. In the present study, to examine how motor costs associated with changes of mind affect perceptual decision making, participants performed a difficult random dot–motion discrimination task in which they had to indicate the direction of motion by reaching to one of two response options. Although each response box was always equidistant from the starting position, the physical distance between the two response options was varied. We found that when the boxes were far apart from one another, and thus changes of mind incurred greater redirection motor costs, change-of-mind frequency decreased while latency to initiate movement increased. This occurred even when response box distance varied randomly from trial to trial and was cued only 1 s before each trial began. Thus, we demonstrated that observers can dynamically adjust perceptual decision-making processes to avoid high motor costs incurred by a change of mind.

  16. Using adaptive sampling and triangular meshes for the processing and inversion of potential field data

    NASA Astrophysics Data System (ADS)

    Foks, Nathan Leon

    The interpretation of geophysical data plays an important role in the analysis of potential field data in resource exploration industries. Two categories of interpretation techniques are discussed in this thesis; boundary detection and geophysical inversion. Fault or boundary detection is a method to interpret the locations of subsurface boundaries from measured data, while inversion is a computationally intensive method that provides 3D information about subsurface structure. My research focuses on these two aspects of interpretation techniques. First, I develop a method to aid in the interpretation of faults and boundaries from magnetic data. These processes are traditionally carried out using raster grid and image processing techniques. Instead, I use unstructured meshes of triangular facets that can extract inferred boundaries using mesh edges. Next, to address the computational issues of geophysical inversion, I develop an approach to reduce the number of data in a data set. The approach selects the data points according to a user specified proxy for its signal content. The approach is performed in the data domain and requires no modification to existing inversion codes. This technique adds to the existing suite of compressive inversion algorithms. Finally, I develop an algorithm to invert gravity data for an interfacing surface using an unstructured mesh of triangular facets. A pertinent property of unstructured meshes is their flexibility at representing oblique, or arbitrarily oriented structures. This flexibility makes unstructured meshes an ideal candidate for geometry based interface inversions. The approaches I have developed provide a suite of algorithms geared towards large-scale interpretation of potential field data, by using an unstructured representation of both the data and model parameters.

  17. Comprehensive processing of high throughput small RNA sequencing data including quality checking, normalization and differential expression analysis using the UEA sRNA Workbench.

    PubMed

    Beckers, Matthew L; Mohorianu, Irina; Stocks, Matthew B; Applegate, Christopher; Dalmay, Tamas; Moulton, Vincent

    2017-03-13

    Recently High Throughput Sequencing (HTS) has revealed compelling details about the small RNA (sRNA) population in eukaryotes. These 20-25 nt non-coding RNAs can influence gene expression by acting as guides for the sequence-specific regulatory mechanism known as RNA silencing. The increase in sequencing depth and number of samples per project enables a better understanding of the role sRNAs play by facilitating the study of expression patterns. However, the intricacy of the biological hypotheses coupled with a lack of appropriate tools often leads to inadequate mining of the available data and thus, an incomplete description of the biological mechanisms involved. To enable a comprehensive study of differential expression in sRNA datasets we present a new interactive pipeline that guides researchers through the various stages of data pre-processing and analysis. This includes various tools, some of which we specifically developed for sRNA analysis, for quality checking and normalization of sRNA samples as well as tools for the detection of differentially expressed sRNAs and identification of the resulting expression patterns. The pipeline is available within the UEA sRNA Workbench, a user-friendly software package for the processing of sRNA datasets. We demonstrate the use of the pipeline on a H. sapiens dataset; additional examples on a B. terrestris dataset and on an A. thaliana dataset are described in the supplementary information. A comparison with existing approaches is also included, which exemplifies some of the issues that need to be addressed for sRNA analysis, and how the new pipeline may be used to do this.

  18. PICH: a DNA translocase specially adapted for processing anaphase bridge DNA.

    PubMed

    Biebricher, Andreas; Hirano, Seiki; Enzlin, Jacqueline H; Wiechens, Nicola; Streicher, Werner W; Huttner, Diana; Wang, Lily H-C; Nigg, Erich A; Owen-Hughes, Tom; Liu, Ying; Peterman, Erwin; Wuite, Gijs J L; Hickson, Ian D

    2013-09-12

    The Plk1-interacting checkpoint helicase (PICH) protein localizes to ultrafine anaphase bridges (UFBs) in mitosis alongside a complex of DNA repair proteins, including the Bloom's syndrome protein (BLM). However, very little is known about the function of PICH or how it is recruited to UFBs. Using a combination of microfluidics, fluorescence microscopy, and optical tweezers, we have defined the properties of PICH in an in vitro model of an anaphase bridge. We show that PICH binds with a remarkably high affinity to duplex DNA, resulting in ATP-dependent protein translocation and extension of the DNA. Most strikingly, the affinity of PICH for binding DNA increases with tension-induced DNA stretching, which mimics the effect of the mitotic spindle on a UFB. PICH binding also appears to diminish force-induced DNA melting. We propose a model in which PICH recognizes and stabilizes DNA under tension during anaphase, thereby facilitating the resolution of entangled sister chromatids.

  19. Walking the Talk: Adopting and Adapting Sustainable Scientific Software Development processes in a Small Biology Lab

    PubMed Central

    Crusoe, Michael R.; Brown, C. Titus

    2016-01-01

    The khmer software project provides both research and production functionality for largescale nucleic-acid sequence analysis. The software implements several novel data structures and algorithms that perform data pre-fltering for common bioinformatics tasks, including sequence mapping and de novo assembly. Development is driven by a small lab with one full-time developer (MRC), as well as several graduate students and a professor (CTB) who contribute regularly to research features. Here we describe our efforts to bring better design, testing, and more open development to the khmer software project as of version 1.1. The khmer software is developed openly at http://github.com/dib-lab/khmer/. PMID:27942385

  20. Adaptive Data Processing Technique for Lidar-Assisted Control to Bridge the Gap between Lidar Systems and Wind Turbines: Preprint

    SciTech Connect

    Schlipf, David; Raach, Steffen; Haizmann, Florian; Cheng, Po Wen; Fleming, Paul; Scholbrock, Andrew, Krishnamurthy, Raghu; Boquet, Mathieu

    2015-12-14

    This paper presents first steps toward an adaptive lidar data processing technique crucial for lidar-assisted control in wind turbines. The prediction time and the quality of the wind preview from lidar measurements depend on several factors and are not constant. If the data processing is not continually adjusted, the benefit of lidar-assisted control cannot be fully exploited, or can even result in harmful control action. An online analysis of the lidar and turbine data are necessary to continually reassess the prediction time and lidar data quality. In this work, a structured process to develop an analysis tool for the prediction time and a new hardware setup for lidar-assisted control are presented. The tool consists of an online estimation of the rotor effective wind speed from lidar and turbine data and the implementation of an online cross correlation to determine the time shift between both signals. Further, initial results from an ongoing campaign in which this system was employed for providing lidar preview for feed-forward pitch control are presented.

  1. Identifying vegetation's influence on multi-scale fluvial processes based on plant trait adaptations

    NASA Astrophysics Data System (ADS)

    Manners, R.; Merritt, D. M.; Wilcox, A. C.; Scott, M.

    2015-12-01

    Riparian vegetation-geomorphic interactions are critical to the physical and biological function of riparian ecosystems, yet we lack a mechanistic understanding of these interactions and predictive ability at the reach to watershed scale. Plant functional groups, or groupings of species that have similar traits, either in terms of a plant's life history strategy (e.g., drought tolerance) or morphology (e.g., growth form), may provide an expression of vegetation-geomorphic interactions. We are developing an approach that 1) identifies where along a river corridor plant functional groups exist and 2) links the traits that define functional groups and their impact on fluvial processes. The Green and Yampa Rivers in Dinosaur National Monument have wide variations in hydrology, hydraulics, and channel morphology, as well as a large dataset of species presence. For these rivers, we build a predictive model of the probable presence of plant functional groups based on site-specific aspects of the flow regime (e.g., inundation probability and duration), hydraulic characteristics (e.g., velocity), and substrate size. Functional group traits are collected from the literature and measured in the field. We found that life-history traits more strongly predicted functional group presence than did morphological traits. However, some life-history traits, important for determining the likelihood of a plant existing along an environmental gradient, are directly related to the morphological properties of the plant, important for the plant's impact on fluvial processes. For example, stem density (i.e., dry mass divided by volume of stem) is positively correlated to drought tolerance and is also related to the modulus of elasticity. Growth form, which is related to the plant's susceptibility to biomass-removing fluvial disturbances, is also related to frontal area. Using this approach, we can identify how plant community composition and distribution shifts with a change to the flow

  2. Computational fluid dynamics simulations of membrane filtration process adapted for water treatment of aerated sewage lagoons.

    PubMed

    Cano, Grégory; Mouahid, Adil; Carretier, Emilie; Guasp, Pascal; Dhaler, Didier; Castelas, Bernard; Moulin, Philippe

    2015-01-01

    The aim of this study is to apply the membrane bioreactor technology in an oxidation ditch in submerged conditions. This new wastewater filtration process will benefit rural areas (<5,000 population equivalent) subject to chronic water shortages by reusing this water for irrigation of green areas. For this purpose, the membranes developed without support are immersed in an aeration well and work in suction mode. The development of the membrane without support and more precisely the performance of spacers are approached by computational fluid dynamics in order to provide the best compromise between pressure drop/flow velocity and permeate flux. The numerical results on the layout and the membrane modules' geometry in the aeration well indicate that the optimal configuration is to install the membranes horizontally on three levels. Membranes should be connected to each other to a manifold providing a total membrane area of 18 m². Loss rate compared to the theoretical throughput is relatively low (less than 3%). Preliminary data obtained by modeling the lagoon provide access to its hydrodynamics, revealing that recirculation zones can be optimized by making changes in the operating conditions. The experimental validation of these results and taking into account the aeration in the numerical models are underway.

  3. Adaptive sparse signal processing of satellite-based radio frequency (RF) recordings of lightning events

    NASA Astrophysics Data System (ADS)

    Moody, Daniela I.; Smith, David A.

    2014-05-01

    Ongoing research at Los Alamos National Laboratory studies the Earth's radio frequency (RF) background utilizing satellite-based RF observations of terrestrial lightning. Such impulsive events are dispersed through the ionosphere and appear as broadband nonlinear chirps at a receiver on-orbit. They occur in the presence of additive noise and structured clutter, making their classification challenging. The Fast On-orbit Recording of Transient Events (FORTE) satellite provided a rich RF lightning database. Application of modern pattern recognition techniques to this database may further lightning research in the scientific community, and potentially improve on-orbit processing and event discrimination capabilities for future satellite payloads. Conventional feature extraction techniques using analytical dictionaries, such as a short-time Fourier basis or wavelets, are not comprehensively suitable for analyzing the broadband RF pulses under consideration here. We explore an alternative approach based on non-analytical dictionaries learned directly from data, and extend two dictionary learning algorithms, K-SVD and Hebbian, for use with satellite RF data. Both algorithms allow us to learn features without relying on analytical constraints or additional knowledge about the expected signal characteristics. We then use a pursuit search over the learned dictionaries to generate sparse classification features, and discuss their performance in terms of event classification. We also use principal component analysis to analyze and compare the respective learned dictionary spaces to the real data space.

  4. Self-adaptive optimal control of dry dual clutch transmission (DCT) during starting process

    NASA Astrophysics Data System (ADS)

    Zhao, Zhiguo; He, Lu; Zheng, Zhengxing; Yang, Yunyun; Wu, Chaochun

    2016-02-01

    An optimal control based on the minimum principle is proposed to solve the problems with the starting process of the self-developed five-speed dry dual clutch transmission (DCT). For the slipping phase, the minimum principle and improved engine constant speed control are adopted to obtain the optimal clutch and engine torques and their rotating speeds, with the minimum jerk intensity and friction work as optimization indices. For the stable running phase, the engine torque is converted to the driver's level of demand. The Matlab/Simulink software platform was used to simulate the DCT vehicle in the starting stage. The simulation and related analysis were conducted for different engine speeds and intentions of the driver. The results showed that the proposed clutch starting control strategy not only reduces the level of jerk and the frictional energy loss but also follows the different starting intentions of the driver. The optimum clutch engagement principle was transformed into the clutch position principle, and a test was carried out on the test bench to validate the effectiveness of the optimum clutch position curve.

  5. Delivering organisational adaptation through legislative mechanisms: Evidence from the Adaptation Reporting Power (Climate Change Act 2008).

    PubMed

    Jude, S R; Drew, G H; Pollard, S J T; Rocks, S A; Jenkinson, K; Lamb, R

    2017-01-01

    There is increasing recognition that organisations, particularly in key infrastructure sectors, are potentially vulnerable to climate change and extreme weather events, and require organisational responses to ensure they are resilient and adaptive. However, detailed evidence of how adaptation is facilitated, implemented and reported, particularly through legislative mechanisms is lacking. The United Kingdom Climate Change Act (2008), introduced the Adaptation Reporting Power, enabling the Government to direct so-called reporting authorities to report their climate change risks and adaptation plans. We describe the authors' unique role and experience supporting the Department for Environment, Food and Rural Affairs (Defra) during the Adaptation Reporting Power's first round. An evaluation framework, used to review the adaptation reports, is presented alongside evidence on how the process provides new insights into adaptation activities and triggered organisational change in 78% of reporting authorities, including the embedding of climate risk and adaptation issues. The role of legislative mechanisms and risk-based approaches in driving and delivering adaptation is discussed alongside future research needs, including the development of organisational maturity models to determine resilient and well adapting organisations. The Adaptation Reporting Power process provides a basis for similar initiatives in other countries, although a clear engagement strategy to ensure buy-in to the process and research on its long-term legacy, including the potential merits of voluntary approaches, is required.

  6. Refraction, including prisms.

    PubMed

    Hiatt, R L

    1991-02-01

    The literature in the past year on refraction is replete with several isolated but very important topics that have been of interest to strabismologists and refractionists for many decades. The refractive changes in scleral buckling procedures include an increase in axial length as well as an increase in myopia, as would be expected. Tinted lenses in dyslexia show little positive effect in the nonasthmatic patients in one study. The use of spectacles or bifocals as a way to control increase in myopia is refuted in another report. It has been shown that in accommodative esotropia not all patients will be able to escape the use of bifocals in the teenage years, even though surgery might be performed. The hope that disposable contact lenses would cut down on the instance of giant papillary conjunctivitis and keratitis has been given some credence, and the conventional theory that sclerosis alone is the cause of presbyopia is attacked. Also, gas permeable bifocal contact lenses are reviewed and the difficulties of correcting presbyopia by this method outlined. The practice of giving an aphakic less bifocal addition instead of a nonaphakic, based on the presumption of increased effective power, is challenged. In the review of prisms, the majority of articles concern prism adaption. The most significant report is that of the Prism Adaptation Study Research Group (Arch Ophthalmol 1990, 108:1248-1256), showing that acquired esotropia in particular has an increased incidence of stable and full corrections surgically in the prism adaptation group versus the control group.(ABSTRACT TRUNCATED AT 250 WORDS)

  7. Deriving site-specific soil clean-up values for metals and metalloids: rationale for including protection of soil microbial processes.

    PubMed

    Kuperman, Roman G; Siciliano, Steven D; Römbke, Jörg; Oorts, Koen

    2014-07-01

    Although it is widely recognized that microorganisms are essential for sustaining soil fertility, structure, nutrient cycling, groundwater purification, and other soil functions, soil microbial toxicity data were excluded from the derivation of Ecological Soil Screening Levels (Eco-SSL) in the United States. Among the reasons for such exclusion were claims that microbial toxicity tests were too difficult to interpret because of the high variability of microbial responses, uncertainty regarding the relevance of the various endpoints, and functional redundancy. Since the release of the first draft of the Eco-SSL Guidance document by the US Environmental Protection Agency in 2003, soil microbial toxicity testing and its use in ecological risk assessments have substantially improved. A wide range of standardized and nonstandardized methods became available for testing chemical toxicity to microbial functions in soil. Regulatory frameworks in the European Union and Australia have successfully incorporated microbial toxicity data into the derivation of soil threshold concentrations for ecological risk assessments. This article provides the 3-part rationale for including soil microbial processes in the development of soil clean-up values (SCVs): 1) presenting a brief overview of relevant test methods for assessing microbial functions in soil, 2) examining data sets for Cu, Ni, Zn, and Mo that incorporated soil microbial toxicity data into regulatory frameworks, and 3) offering recommendations on how to integrate the best available science into the method development for deriving site-specific SCVs that account for bioavailability of metals and metalloids in soil. Although the primary focus of this article is on the development of the approach for deriving SCVs for metals and metalloids in the United States, the recommendations provided in this article may also be applicable in other jurisdictions that aim at developing ecological soil threshold values for protection of

  8. Deriving site-specific soil clean-up values for metals and metalloids: Rationale for including protection of soil microbial processes

    PubMed Central

    Kuperman, Roman G; Siciliano, Steven D; Römbke, Jörg; Oorts, Koen

    2014-01-01

    Although it is widely recognized that microorganisms are essential for sustaining soil fertility, structure, nutrient cycling, groundwater purification, and other soil functions, soil microbial toxicity data were excluded from the derivation of Ecological Soil Screening Levels (Eco-SSL) in the United States. Among the reasons for such exclusion were claims that microbial toxicity tests were too difficult to interpret because of the high variability of microbial responses, uncertainty regarding the relevance of the various endpoints, and functional redundancy. Since the release of the first draft of the Eco-SSL Guidance document by the US Environmental Protection Agency in 2003, soil microbial toxicity testing and its use in ecological risk assessments have substantially improved. A wide range of standardized and nonstandardized methods became available for testing chemical toxicity to microbial functions in soil. Regulatory frameworks in the European Union and Australia have successfully incorporated microbial toxicity data into the derivation of soil threshold concentrations for ecological risk assessments. This article provides the 3-part rationale for including soil microbial processes in the development of soil clean-up values (SCVs): 1) presenting a brief overview of relevant test methods for assessing microbial functions in soil, 2) examining data sets for Cu, Ni, Zn, and Mo that incorporated soil microbial toxicity data into regulatory frameworks, and 3) offering recommendations on how to integrate the best available science into the method development for deriving site-specific SCVs that account for bioavailability of metals and metalloids in soil. Although the primary focus of this article is on the development of the approach for deriving SCVs for metals and metalloids in the United States, the recommendations provided in this article may also be applicable in other jurisdictions that aim at developing ecological soil threshold values for protection of

  9. Adaptation to recent conflict in the classical color-word Stroop-task mainly involves facilitation of processing of task-relevant information

    PubMed Central

    Purmann, Sascha; Pollmann, Stefan

    2015-01-01

    To process information selectively and to continuously fine-tune selectivity of information processing are important abilities for successful goal-directed behavior. One phenomenon thought to represent this fine-tuning are conflict adaptation effects in interference tasks, i.e., reduction of interference after an incompatible trial and when incompatible trials are frequent. The neurocognitive mechanisms of these effects are currently only partly understood and results from brainimaging studies so far are mixed. In our study we validate and extend recent findings by examining adaption to recent conflict in the classical Stroop task using functional magnetic resonance imaging. Consistent with previous research we found increased activity in a fronto-parietal network comprising the medial prefrontal cortex, ventro-lateral prefrontal cortex, and posterior parietal cortex when contrasting incompatible with compatible trials. These areas have been associated with attentional processes and might reflect increased cognitive conflict and resolution thereof during incompatible trials. While carefully controlling for non-attentional sequential effects we found smaller Stroop interference after an incompatible trial (conflict adaptation effect). These behavioral conflict adaptation effects were accompanied by changes in activity in visual color-selective areas (V4, V4α), while there was no modulation by previous trial compatibility in a visual word-selective area (VWFA). Our results provide further evidence for the notion, that adaptation to recent conflict seems to be based mainly on enhancement of processing of the task-relevant information. PMID:25784868

  10. Effects of ripening stage and steaming time on quality attributes of fat free banana snack obtained from drying process including fluidized bed puffing.

    PubMed

    Prachayawarakorn, Somkiat; Raikham, Chonlada; Soponronnarit, Somchart

    2016-02-01

    Healthy snacks have increasingly been interested in consumers. Puffing technique is an alternative to produce healthy snacks. Effects of ripening stage of banana and steaming time on quality of banana slices obtained from drying process including fluidized bed puffing were investigated. Bananas at the ripening stages 1 and 3 were steamed at 100 °C for 30 s up to 2 min and dried at 90 °C to moisture content of 25 % dry basis (d.b.). The samples were then puffed by fluidized bed dryer at 160 °C for 2 min and dried at the same temperature as the first stage drying. The experimental results showed that shrinkage, drying time, color, glycemic index and textural properties were affected by steaming time and ripening stage. Steaming provided more uniformity of banana color. Steaming positively or negatively affected the degree shrinkage of banana depending on the ripening stage. The banana texture in particular crispiness could be improved by the steaming for the ripening stage 1 banana whilst it did not improve for the ripening stage 3. During steaming, the C-type crystalline structure of banana starch disappeared and thus the value of glycemic index was increased. The ripening stage 1 banana was recommended for producing healthy snack in order to control glycemic response.

  11. Adaptive Epibiochemistry and Epigenetics.

    PubMed

    Buryanov, Ya I

    2015-09-01

    Enzymatic reactions of post-synthetic modification of macromolecules occur in the cells of all organisms. These reactions, which can be designated as epibiochemical, are of a special type and, as discriminated from reactions with low molecular weight substrates, occur on the level of biopolymers, causing their covalent modification. The majority of epibiochemical modifications of proteins, DNA, and RNA are reversible and are carried out by modification transferases and de-modification enzymes, respectively. Epibiochemical, i.e. those located above the low molecular weight metabolites, modifications of proteins and nucleic acids perform various functions, including participation in molecular mechanisms of adaptive epigenetic heredity. This paper presents an overview of some adaptive epibiochemical modifications of macromolecules and the adaptive epigenetic processes on their basis. The features of epigenetic inheritance of acquired characteristics and the limits of biological evolution are discussed.

  12. Big-bang nucleosynthesis with a long-lived charged massive particle including {sup 4}He spallation processes in a bound state

    SciTech Connect

    Jittoh, Toshifumi; Kohri, Kazunori; Koike, Masafumi; Sato, Joe; Sugai, Kenichi; Yamanaka, Masato; Yazaki, Koichi

    2012-07-27

    We propose helium-4 spallation processes induced by long-lived stau in supersymmetric standard models, and investigate an impact of the processes on light elements abundances. We show that, as long as the phase space of helium-4 spallation processes is open, they are more important than stau-catalyzed fusion and hence constrain the stau property.

  13. The longevity of adaptive memory: evidence for mnemonic advantages of survival processing 24 and 48 hours later.

    PubMed

    Raymaekers, Linsey H C; Otgaar, Henry; Smeets, Tom

    2014-01-01

    Prior studies have convincingly demonstrated that survival-related processing of information enhances its subsequent retention. This phenomenon, known as the survival recall advantage, generalises to other stimuli, memory domains, and research populations, thereby underscoring its reliability. As previous studies used only short retention intervals between survival processing and the memory test, an important yet hitherto unanswered issue is whether this effect persists over time. The present experiment therefore examined whether survival processing also produces mnemonic benefits when retention is tested after longer delay periods. Participants (N =81) rated the relevance of words according to a survival and a moving scenario, and were then randomly assigned to the typical immediate (3-minute delay) retention test condition or conditions that included a 24- or 48-hour interval between survival processing and memory testing. In each of these conditions survival processing led to higher surprise free recall and recognition rates than processing words according to the moving scenario. Thus this study provides evidence that illustrates the longevity of survival processing advantages on memory performance.

  14. The TAL effector PthA4 interacts with nuclear factors involved in RNA-dependent processes including a HMG protein that selectively binds poly(U) RNA.

    PubMed

    de Souza, Tiago Antonio; Soprano, Adriana Santos; de Lira, Nayara Patricia Vieira; Quaresma, Alexandre José Christino; Pauletti, Bianca Alves; Paes Leme, Adriana Franco; Benedetti, Celso Eduardo

    2012-01-01

    Plant pathogenic bacteria utilize an array of effector proteins to cause disease. Among them, transcriptional activator-like (TAL) effectors are unusual in the sense that they modulate transcription in the host. Although target genes and DNA specificity of TAL effectors have been elucidated, how TAL proteins control host transcription is poorly understood. Previously, we showed that the Xanthomonas citri TAL effectors, PthAs 2 and 3, preferentially targeted a citrus protein complex associated with transcription control and DNA repair. To extend our knowledge on the mode of action of PthAs, we have identified new protein targets of the PthA4 variant, required to elicit canker on citrus. Here we show that all the PthA4-interacting proteins are DNA and/or RNA-binding factors implicated in chromatin remodeling and repair, gene regulation and mRNA stabilization/modification. The majority of these proteins, including a structural maintenance of chromosomes protein (CsSMC), a translin-associated factor X (CsTRAX), a VirE2-interacting protein (CsVIP2), a high mobility group (CsHMG) and two poly(A)-binding proteins (CsPABP1 and 2), interacted with each other, suggesting that they assemble into a multiprotein complex. CsHMG was shown to bind DNA and to interact with the invariable leucine-rich repeat region of PthAs. Surprisingly, both CsHMG and PthA4 interacted with PABP1 and 2 and showed selective binding to poly(U) RNA, a property that is novel among HMGs and TAL effectors. Given that homologs of CsHMG, CsPABP1, CsPABP2, CsSMC and CsTRAX in other organisms assemble into protein complexes to regulate mRNA stability and translation, we suggest a novel role of TAL effectors in mRNA processing and translational control.

  15. Adaptive smoothing based on Gaussian processes regression increases the sensitivity and specificity of fMRI data.

    PubMed

    Strappini, Francesca; Gilboa, Elad; Pitzalis, Sabrina; Kay, Kendrick; McAvoy, Mark; Nehorai, Arye; Snyder, Abraham Z

    2017-03-01

    Temporal and spatial filtering of fMRI data is often used to improve statistical power. However, conventional methods, such as smoothing with fixed-width Gaussian filters, remove fine-scale structure in the data, necessitating a tradeoff between sensitivity and specificity. Specifically, smoothing may increase sensitivity (reduce noise and increase statistical power) but at the cost loss of specificity in that fine-scale structure in neural activity patterns is lost. Here, we propose an alternative smoothing method based on Gaussian processes (GP) regression for single subjects fMRI experiments. This method adapts the level of smoothing on a voxel by voxel basis according to the characteristics of the local neural activity patterns. GP-based fMRI analysis has been heretofore impractical owing to computational demands. Here, we demonstrate a new implementation of GP that makes it possible to handle the massive data dimensionality of the typical fMRI experiment. We demonstrate how GP can be used as a drop-in replacement to conventional preprocessing steps for temporal and spatial smoothing in a standard fMRI pipeline. We present simulated and experimental results that show the increased sensitivity and specificity compared to conventional smoothing strategies. Hum Brain Mapp 38:1438-1459, 2017. © 2016 Wiley Periodicals, Inc.

  16. Orality and Literacy in the Workplace: Process- and Text-Based Strategies for Multiple-Audience Adaptation.

    ERIC Educational Resources Information Center

    Spilka, Rachel

    1990-01-01

    Examines the role of orality in multiple-audience analysis and adaptation. Finds that interaction is the central means of analyzing and adapting discourse to multiple audiences, fulfilling rhetorical and social goals, and building and sustaining a corporate culture. Suggests that orality is more potent than literacy in composing behavior and…

  17. An application of space-time adaptive processing to airborne and spaceborne monostatic and bistatic radar systems

    NASA Astrophysics Data System (ADS)

    Czernik, Richard James

    A challenging problem faced by Ground Moving Target Indicator (GMTI) radars on both airborne and spaceborne platforms is the ability to detect slow moving targets due the presence of non-stationary and heterogeneous ground clutter returns. Space-Time Adaptive Processing techniques process both the spatial signals from an antenna array as well as radar pulses simultaneously to aid in mitigating this clutter which has an inherent Doppler shift due to radar platform motion, as well as spreading across Angle-Doppler space attributable to a variety of factors. Additional problems such as clutter aliasing, widening of the clutter notch, and range dependency add additional complexity when the radar is bistatic in nature, and vary significantly as the bistatic radar geometry changes with respect to the targeted location. The most difficult situation is that of a spaceborne radar system due to its high velocity and altitude with respect to the earth. A spaceborne system does however offer several advantages over an airborne system, such as the ability to cover wide areas and to provide access to areas denied to airborne platforms. This dissertation examines both monostatic and bistatic radar performance based upon a computer simulation developed by the author, and explores the use of both optimal STAP and reduced dimension STAP architectures to mitigate the modeled clutter returns. Factors such as broadband jamming, wind, and earth rotation are considered, along with their impact on the interference covariance matrix, constructed from sample training data. Calculation of the covariance matrix in near real time based upon extracted training data is computer processor intensive and reduced dimension STAP architectures relieve some of the computation burden. The problems resulting from extending both monostatic and bistatic radar systems to space are also simulated and studied.

  18. Recent advances in use of magnesium-enhanced FGD processes include a natural oxidation limestone scrubber conversion and the first commercial ThioClear{reg_sign} application

    SciTech Connect

    Smith, K.; Babu, M.; Inkenhaus, W.

    1998-04-01

    The magnesium-enhanced Thiosorbic FGD process, originally developed by the Dravo Lime Company (DLC) in the early 1970`s, is used by over 1400 MW of power generation in the US primarily by high sulfur coal burning utilities. The excellent SO{sub 2} removal efficiencies, high reliability, and cost effectiveness are the hallmarks of this process. DLC personnel working with Alabama Electric Cooperative`s (AEC) personnel converted AEC`s Units 2 and 3 at the Lowman Station in Alabama from limestone scrubbing to magnesium-enhanced lime scrubbing process in early 1996. These units totaling 516 MW have been in continuous operation, enabling AEC to save on fuel costs by switching to a lower cost, higher sulfur containing coal, made possible by the higher removal efficiency Thiosorbic process modification. The first part of this paper details the modifications that were made and compares the performance differences between the limestone and Thiosorbic FGD processes. ThioClear{reg_sign} FGD is a forced oxidized magnesium-enhanced lime scrubbing process that produces high quality gypsum and magnesium hydroxide as by-products. The recycle liquor in this process is nearly clear and the capability for SO{sub 2} removal is as high as the Thiosorbic process. DLC working with Applied Energy Systems (AES) of Monaca, Pennsylvania, is currently constructing a 130 Mwe station modification to convert from the natural oxidation Thiosorbic process to the forced oxidation ThioClear{reg_sign} process. The plant is scheduled to start up by the end of the third quarter of this year. The second part of this paper details the ThioClear process modifications at AES and describes the by-ducts and their potential uses.

  19. Recent advances in use of magnesium-enhanced FGD processes include a natural oxidation limestone scrubber conversion and the first commercial ThioClear{reg{underscore}sign} application

    SciTech Connect

    Smith, K.; Babu, M; Inkenhaus, W.

    1998-07-01

    The magnesium-enhanced Thiosorbic FGD process, originally developed by the Dravo Lime Company (DLC) in the early 1970's, is used by over 1,400 MW of power generation in the US primarily by high sulfur coal burning utilities. The excellent SO{sub 2} removal efficiencies, high reliability, and cost effectiveness are the hallmarks of this process. DLC personnel working with Alabama Electric Cooperative's (AEC) personnel converted AEC's Units 2 and 3 at the Lowman Station in Alabama from limestone scrubbing to magnesium-enhanced lime scrubbing process in early 1996. These units totaling 516 MW have been in continuous operation, enabling AEC to save on fuel costs by switching to a lower cost, higher sulfur containing coal, made possible by the higher removal efficiency Thiosorbic process modification. The first part of this paper details the modification that were made and compares the performance differences between the limestone and Thiosorbic FGD processes. ThioClear{reg{underscore}sign} FGD is a forced oxidized magnesium-enhanced lime scrubbing process that produces high quality gypsum and magnesium hydroxide as by-products. The recycle liquor in this process is nearly clear and the capability for SO{sub 2} removal is as high as the Thiosorbic process. DLC working with Applied Energy Systems (AES) of Monaca, Pennsylvania, is currently constructing a 130 Mwe station modification to convert from the natural oxidation Thiosorbic process to the forced oxidation ThioClear{reg{underscore}sign} process. The plant is scheduled to start up by the end of the third quarter of this year. The second part oft his paper details the ThioClear process modifications at AES and describes the by-products and their potential uses.

  20. Development of a Computerized Adaptive Testing for Diagnosing the Cognitive Process of Grade 7 Students in Learning Algebra, Using Multidimensional Item Response Theory

    ERIC Educational Resources Information Center

    Senarat, Somprasong; Tayraukham, Sombat; Piyapimonsit, Chatsiri; Tongkhambanjong, Sakesan

    2013-01-01

    The purpose of this research is to develop a multidimensional computerized adaptive test for diagnosing the cognitive process of grade 7 students in learning algebra by applying multidimensional item response theory. The research is divided into 4 steps: 1) the development of item bank of algebra, 2) the development of the multidimensional…

  1. Climate adaptation planning in practice: an evaluation of adaptation plans from three developed nations

    SciTech Connect

    Preston, Benjamin L; Westaway, Richard M.; Yuen, Emma J.

    2011-04-01

    Formal planning for climate change adaptation is emerging rapidly at a range of geo-political scales. This first generation of adaptation plans provides useful information regarding how institutions are framing the issue of adaptation and the range of processes that are recognized as being part of an adaptation response. To better understand adaptation planning among developed nations, a set of 57 adaptation plans from Australia, the United Kingdom and the United States was evaluated against a suite of 19 planning processes identified from existing guidance instruments for adaptation planning. Total scores among evaluated plans ranged from 16% of the maximum possible score to 61%, with an average of 37%. These results suggest adaptation plans are largely under-developed. Critical weaknesses in adaptation planning are related to limited consideration for non-climatic factors as well as neglect for issues of adaptive capacity including entitlements to various forms of capital needed for effective adaptation. Such gaps in planning suggest there are opportunities for institutions to make better use of existing guidance for adaptation planning and the need to consider the broader governance context in which adaptation will occur. In addition, the adaptation options prescribed by adaptation plans reflect a preferential bias toward low-risk capacity-building (72% of identified options) over the delivery of specific actions to reduce vulnerability. To the extent these findings are representative of the state of developed nation adaptation planning, there appear to be significant deficiencies in climate change preparedness, even among those nations often assumed to have the greatest adaptive capacity.

  2. The Adaptation of a School-Based Health Promotion Programme for Youth with Intellectual and Developmental Disabilities: A Community-Engaged Research Process

    ERIC Educational Resources Information Center

    Hubbard, Kristie L.; Bandini, Linda G.; Folta, Sara C.; Wansink, Brian; Must, Aviva

    2014-01-01

    Background: Evidenced-based health promotion programmes for youth with intellectual and developmental disabilities (I/DD) are notably absent. Barriers include a lack of understanding of how to adapt existing evidence-based programmes to their needs, maximize inclusion and support mutual goals of health and autonomy. Methods: We undertook a…

  3. The influence of regional urbanization and abnormal weather conditions on the processes of human climatic adaptation on mountain resorts

    NASA Astrophysics Data System (ADS)

    Artamonova, M.; Golitsyn, G.; Senik, I.; Safronov, A.; Babyakin, A.; Efimenko, N.; Povolotskaya, N.; Topuriya, D.; Chalaya, E.

    2012-04-01

    This work is a further development in the study of weather pathogenic index (WPI) and negative influence of urbanization processes on the state of people's health with adaptation disorder. This problem is socially significant. According to the data of the WHO, in the world there are from 20 to 45% of healthy people and from 40 to 80% of people with chronic diseases who suffer from the raised meteosensitivity. As a result of our researches of meteosensitivity of people during their short-duration on mountain resorts there were used negative adaptive reactions (NAR) under 26 routine tests, stress-reactions under L.H. Garkavi's hemogram, vegetative indices, tests of neuro-vascular reactivity, signs of imbalance of vegetative and neurohumoral regulation according to the data of biorhythm fractal analysis and sudden aggravations of diseases (SAD) as an indicator of negative climatic and urbanization influence. In 2010-2011 the Caucasian mountain resorts were having long periods of climatic anomalies, strengthening of anthropogenic emissions and forest fires when record-breaking high waves of NAR and SAD were noticed. There have also been specified indices ranks of weather pathogenicity from results of comparison of health characteristics with indicators of synoptico-dynamic processes according to Weather Research and Forecasting model (WRF); air ionization N+, N-, N+/N- spectra of aerosol particles (the size from 500 to 20000 nanometers) and concentrations of chemically active gases (O3, NO, NO2, ), volatile phytoorganic substances in the surface atmosphere, bactericidal characteristics of vegetation by criterion χ2 (not above 0,05). It has allowed us to develop new physiological optimum borders, norm and pessimum, to classify emergency ecologo-weather situations, to develop a new techniques of their forecasting and prevention of meteopathic reactions with meteosensitive patients (Method of treatment and the early (emergency) and planned prevention meteopatic reactions

  4. Numerical modelling of physical processes in a ballistic laboratory setup with a tapered adapter and plastic piston used for obtaining high muzzle velocities

    NASA Astrophysics Data System (ADS)

    Bykov, N. V.

    2014-12-01

    Numerical modelling of a ballistic setup with a tapered adapter and plastic piston is considered. The processes in the firing chamber are described within the framework of quasi- one-dimensional gas dynamics and a geometrical law of propellant burn by means of Lagrangian mass coordinates. The deformable piston is considered to be an ideal liquid with specific equations of state. The numerical solution is obtained by means of a modified explicit von Neumann scheme. The calculation results given show that the ballistic setup with a tapered adapter and plastic piston produces increased shell muzzle velocities by a factor of more than 1.5-2.

  5. Adaptive Iterative Dose Reduction Using Three Dimensional Processing (AIDR3D) Improves Chest CT Image Quality and Reduces Radiation Exposure

    PubMed Central

    Yamashiro, Tsuneo; Miyara, Tetsuhiro; Honda, Osamu; Kamiya, Hisashi; Murata, Kiyoshi; Ohno, Yoshiharu; Tomiyama, Noriyuki; Moriya, Hiroshi; Koyama, Mitsuhiro; Noma, Satoshi; Kamiya, Ayano; Tanaka, Yuko; Murayama, Sadayuki

    2014-01-01

    Objective To assess the advantages of Adaptive Iterative Dose Reduction using Three Dimensional Processing (AIDR3D) for image quality improvement and dose reduction for chest computed tomography (CT). Methods Institutional Review Boards approved this study and informed consent was obtained. Eighty-eight subjects underwent chest CT at five institutions using identical scanners and protocols. During a single visit, each subject was scanned using different tube currents: 240, 120, and 60 mA. Scan data were converted to images using AIDR3D and a conventional reconstruction mode (without AIDR3D). Using a 5-point scale from 1 (non-diagnostic) to 5 (excellent), three blinded observers independently evaluated image quality for three lung zones, four patterns of lung disease (nodule/mass, emphysema, bronchiolitis, and diffuse lung disease), and three mediastinal measurements (small structure visibility, streak artifacts, and shoulder artifacts). Differences in these scores were assessed by Scheffe's test. Results At each tube current, scans using AIDR3D had higher scores than those without AIDR3D, which were significant for lung zones (p<0.0001) and all mediastinal measurements (p<0.01). For lung diseases, significant improvements with AIDR3D were frequently observed at 120 and 60 mA. Scans with AIDR3D at 120 mA had significantly higher scores than those without AIDR3D at 240 mA for lung zones and mediastinal streak artifacts (p<0.0001), and slightly higher or equal scores for all other measurements. Scans with AIDR3D at 60 mA were also judged superior or equivalent to those without AIDR3D at 120 mA. Conclusion For chest CT, AIDR3D provides better image quality and can reduce radiation exposure by 50%. PMID:25153797

  6. Processes Driving the Adaptive Radiation of a Tropical Tree (Diospyros, Ebenaceae) in New Caledonia, a Biodiversity Hotspot.

    PubMed

    Paun, Ovidiu; Turner, Barbara; Trucchi, Emiliano; Munzinger, Jérôme; Chase, Mark W; Samuel, Rosabelle

    2016-03-01

    Due to its special geological history, the New Caledonian Archipelago is a mosaic of soil types, and in combination with climatic conditions this results in a heterogeneous environment across relatively small distances. A group of over 20 endemic species of Diospyros (Ebenaceae) has rapidly and recently radiated on the archipelago after a single long-distance dispersal event. Most of the Diospyros species in the radiating group are morphologically and ecologically well differentiated, but they exhibit low levels of DNA variability. To investigate the processes that shaped the diversification of this group we employed restriction site associated DNA sequencing (RADseq). Over 8400 filtered SNPs generally confirm species delimitations and produce a well-supported phylogenetic tree. Our analyses document local introgression, but only a limited potential for gene flow over longer distances. The phylogenetic relationships point to an early regional clustering among populations and species, indicating that allopatric speciation with respect to macrohabitat (i.e., climatic conditions) may have had a role in the initial differentiation within the group. A later, more rapid radiation involved divergence with respect to microhabitat (i.e., soil preference). Several sister species in the group show a parallel divergence in edaphic preference. Searches for genomic regions that are systematically differentiated in this replicated phenotypic divergence pointed to loci potentially involved in ion binding and cellular transport. These loci appear meaningful in the context of adaptations to soil types that differ in heavy-metal and mineral content. Identical nucleotide changes affected only two of these loci, indicating that introgression may have played a limited role in their evolution. Our results suggest that both allopatric diversification and (parapatric) ecological divergence shaped successive rounds of speciation in the Diospyros radiation on New Caledonia.

  7. Processes Driving the Adaptive Radiation of a Tropical Tree (Diospyros, Ebenaceae) in New Caledonia, a Biodiversity Hotspot

    PubMed Central

    Paun, Ovidiu; Turner, Barbara; Trucchi, Emiliano; Munzinger, Jérôme; Chase, Mark W.; Samuel, Rosabelle

    2016-01-01

    Due to its special geological history, the New Caledonian Archipelago is a mosaic of soil types, and in combination with climatic conditions this results in a heterogeneous environment across relatively small distances. A group of over 20 endemic species of Diospyros (Ebenaceae) has rapidly and recently radiated on the archipelago after a single long-distance dispersal event. Most of the Diospyros species in the radiating group are morphologically and ecologically well differentiated, but they exhibit low levels of DNA variability. To investigate the processes that shaped the diversification of this group we employed restriction site associated DNA sequencing (RADseq). Over 8400 filtered SNPs generally confirm species delimitations and produce a well-supported phylogenetic tree. Our analyses document local introgression, but only a limited potential for gene flow over longer distances. The phylogenetic relationships point to an early regional clustering among populations and species, indicating that allopatric speciation with respect to macrohabitat (i.e., climatic conditions) may have had a role in the initial differentiation within the group. A later, more rapid radiation involved divergence with respect to microhabitat (i.e., soil preference). Several sister species in the group show a parallel divergence in edaphic preference. Searches for genomic regions that are systematically differentiated in this replicated phenotypic divergence pointed to loci potentially involved in ion binding and cellular transport. These loci appear meaningful in the context of adaptations to soil types that differ in heavy-metal and mineral content. Identical nucleotide changes affected only two of these loci, indicating that introgression may have played a limited role in their evolution. Our results suggest that both allopatric diversification and (parapatric) ecological divergence shaped successive rounds of speciation in the Diospyros radiation on New Caledonia. PMID:26430059

  8. Adapting the Electrospinning Process to Provide Three Unique Environments for a Tri-layered In Vitro Model of the Airway Wall

    PubMed Central

    Bridge, Jack C.; Aylott, Jonathan W.; Brightling, Christopher E.; Ghaemmaghami, Amir M.; Knox, Alan J.; Lewis, Mark P.; Rose, Felicity R.A.J.; Morris, Gavin E.

    2015-01-01

    Electrospinning is a highly adaptable method producing porous 3D fibrous scaffolds that can be exploited in in vitro cell culture. Alterations to intrinsic parameters within the process allow a high degree of control over scaffold characteristics including fiber diameter, alignment and porosity. By developing scaffolds with similar dimensions and topographies to organ- or tissue-specific extracellular matrices (ECM), micro-environments representative to those that cells are exposed to in situ can be created. The airway bronchiole wall, comprised of three main micro-environments, was selected as a model tissue. Using decellularized airway ECM as a guide, we electrospun the non-degradable polymer, polyethylene terephthalate (PET), by three different protocols to produce three individual electrospun scaffolds optimized for epithelial, fibroblast or smooth muscle cell-culture. Using a commercially available bioreactor system, we stably co-cultured the three cell-types to provide an in vitro model of the airway wall over an extended time period. This model highlights the potential for such methods being employed in in vitro diagnostic studies investigating important inter-cellular cross-talk mechanisms or assessing novel pharmaceutical targets, by providing a relevant platform to allow the culture of fully differentiated adult cells within 3D, tissue-specific environments. PMID:26275100

  9. Adapting the Electrospinning Process to Provide Three Unique Environments for a Tri-layered In Vitro Model of the Airway Wall.

    PubMed

    Bridge, Jack C; Aylott, Jonathan W; Brightling, Christopher E; Ghaemmaghami, Amir M; Knox, Alan J; Lewis, Mark P; Rose, Felicity R A J; Morris, Gavin E

    2015-07-31

    Electrospinning is a highly adaptable method producing porous 3D fibrous scaffolds that can be exploited in in vitro cell culture. Alterations to intrinsic parameters within the process allow a high degree of control over scaffold characteristics including fiber diameter, alignment and porosity. By developing scaffolds with similar dimensions and topographies to organ- or tissue-specific extracellular matrices (ECM), micro-environments representative to those that cells are exposed to in situ can be created. The airway bronchiole wall, comprised of three main micro-environments, was selected as a model tissue. Using decellularized airway ECM as a guide, we electrospun the non-degradable polymer, polyethylene terephthalate (PET), by three different protocols to produce three individual electrospun scaffolds optimized for epithelial, fibroblast or smooth muscle cell-culture. Using a commercially available bioreactor system, we stably co-cultured the three cell-types to provide an in vitro model of the airway wall over an extended time period. This model highlights the potential for such methods being employed in in vitro diagnostic studies investigating important inter-cellular cross-talk mechanisms or assessing novel pharmaceutical targets, by providing a relevant platform to allow the culture of fully differentiated adult cells within 3D, tissue-specific environments.

  10. Implications of Childhood Experiences for the Health and Adaptation of Lesbian, Gay, and Bisexual Individuals: Sensitivity to Developmental Process in Future Research

    PubMed Central

    Rosario, Margaret

    2015-01-01

    The empirical literature on lesbian, gay, and bisexual (LGB) individuals has predominantly focused on sexual-orientation disparities between LGB and heterosexual individuals on health and adaptation, as well as on the role of gay-related or minority stress in the health and adaptation of LGB individuals. Aside from demographic control variables, the initial predictor is a marker of sexual orientation or LGB-related experience (e.g., minority stress). Missing are potential strengths and vulnerabilities that LGB individuals develop over time and bring to bear on their sexual identity development and other LGB-related experiences. Those strengths and vulnerabilities may have profound consequences for the sexual identity development, health, and adaptation of LGB individuals. Here, I focus on one such set of strengths and vulnerabilities derived from attachment. I conclude by emphasizing the importance of attachment in the lives of LGB individuals and the need to identify other developmental processes that may be equally consequential. PMID:26900586

  11. Even in Sweden? Excluding the Included: Some Reflections on the Consequences of New Policies on Educational Processes and Outcomes, and Equity in Education

    ERIC Educational Resources Information Center

    Berhanu, Girma

    2010-01-01

    The purpose of this article is to reflect on the effects of educational reforms (which are guided by a neoliberal political agenda) on educational processes, outcomes, and inclusive education in Sweden. It is focused in particular on the increasing marginalisation and exclusion of students with special educational needs, immigrant students, and…

  12. Psychometric evaluation of the Swedish adaptation of the Inventory for Assessing the Process of Cultural Competence Among Healthcare Professionals--Revised (IAPCC-R).

    PubMed

    Olt, Helen; Jirwe, Maria; Gustavsson, Petter; Emami, Azita

    2010-01-01

    The purpose of this study was to describe the translation, adaption, and psychometric evaluation process in relation to validity and reliability of the Swedish version of the instrument, Inventory for Assessing The Process of Cultural Competence Among Healthcare Professionals-Revised (IAPCC-R) following the translation, adaptation, and psychometric evaluation process. Validity tests were conducted on the response processes (N = 15), the content (N = 7), and the internal structure of the instrument (N = 334). Reliability (alpha = .65 for the total scale varying between -.01 and .65 for the different subscales) was evaluated in terms of internal consistency. Results indicated weak validity and reliability though it is difficult to conclude whether this is related to adaptation issues or the original construction.The testing of the response process identified problems in relation to respondents' conceptualization of cultural competence. The test of the content identified a weak correspondence between the items and the underlying model. In addition, a confirmatory factor analysis did not confirm the proposed structure of the instrument. This study concludes that this instrument is not valid and reliable for use with a Swedish population of practicing nurses or nursing students.

  13. Evaluation of an Adaptive Game that Uses EEG Measures Validated during the Design Process as Inputs to a Biocybernetic Loop

    PubMed Central

    Ewing, Kate C.; Fairclough, Stephen H.; Gilleade, Kiel

    2016-01-01

    Biocybernetic adaptation is a form of physiological computing whereby real-time data streaming from the brain and body is used by a negative control loop to adapt the user interface. This article describes the development of an adaptive game system that is designed to maximize player engagement by utilizing changes in real-time electroencephalography (EEG) to adjust the level of game demand. The research consists of four main stages: (1) the development of a conceptual framework upon which to model the interaction between person and system; (2) the validation of the psychophysiological inference underpinning the loop; (3) the construction of a working prototype; and (4) an evaluation of the adaptive game. Two studies are reported. The first demonstrates the sensitivity of EEG power in the (frontal) theta and (parietal) alpha bands to changing levels of game demand. These variables were then reformulated within the working biocybernetic control loop designed to maximize player engagement. The second study evaluated the performance of an adaptive game of Tetris with respect to system behavior and user experience. Important issues for the design and evaluation of closed-loop interfaces are discussed. PMID:27242486

  14. Evaluation of an Adaptive Game that Uses EEG Measures Validated during the Design Process as Inputs to a Biocybernetic Loop.

    PubMed

    Ewing, Kate C; Fairclough, Stephen H; Gilleade, Kiel

    2016-01-01

    Biocybernetic adaptation is a form of physiological computing whereby real-time data streaming from the brain and body is used by a negative control loop to adapt the user interface. This article describes the development of an adaptive game system that is designed to maximize player engagement by utilizing changes in real-time electroencephalography (EEG) to adjust the level of game demand. The research consists of four main stages: (1) the development of a conceptual framework upon which to model the interaction between person and system; (2) the validation of the psychophysiological inference underpinning the loop; (3) the construction of a working prototype; and (4) an evaluation of the adaptive game. Two studies are reported. The first demonstrates the sensitivity of EEG power in the (frontal) theta and (parietal) alpha bands to changing levels of game demand. These variables were then reformulated within the working biocybernetic control loop designed to maximize player engagement. The second study evaluated the performance of an adaptive game of Tetris with respect to system behavior and user experience. Important issues for the design and evaluation of closed-loop interfaces are discussed.

  15. Vulnerability to climate change and adaptation strategies of local communities in Malawi: experiences of women fish-processing groups in the Lake Chilwa Basin

    NASA Astrophysics Data System (ADS)

    Jørstad, Hanne; Webersik, Christian

    2016-12-01

    In recent years, research on climate change and human security has received much attention among policy makers and academia alike. Communities in the Global South that rely on an intact resource base and struggle with poverty, existing inequalities and historical injustices will especially be affected by predicted changes in temperature and precipitation. The objective of this article is to better understand under what conditions local communities can adapt to anticipated impacts of climate change. The empirical part of the paper answers the question as to what extent local women engaged in fish processing in the Chilwa Basin in Malawi have experienced climate change and how they are affected by it. The article assesses an adaptation project designed to make those women more resilient to a warmer and more variable climate. The research results show that marketing and improving fish processing as strategies to adapt to climate change have their limitations. The study concludes that livelihood diversification can be a more effective strategy for Malawian women to adapt to a more variable and unpredictable climate rather than exclusively relying on a resource base that is threatened by climate change.

  16. Structure and Properties of Ti-19.7Nb-5.8Ta Shape Memory Alloy Subjected to Thermomechanical Processing Including Aging

    NASA Astrophysics Data System (ADS)

    Dubinskiy, S.; Brailovski, Vladimir; Prokoshkin, S.; Pushin, V.; Inaekyan, K.; Sheremetyev, V.; Petrzhik, M.; Filonov, M.

    2013-09-01

    In this work, the ternary Ti-19.7Nb-5.8Ta (at.%) alloy for biomedical applications was studied. The ingot was manufactured by vacuum arc melting with a consumable electrode and then subjected to hot forging. Specimens were cut from the ingot and processed by cold rolling with e = 0.37 of logarithmic thickness reduction and post-deformation annealing (PDA) between 400 and 750 °C (1 h). Selected samples were subjected to aging at 300 °C (10 min to 3 h). The influence of the thermomechanical processing on the alloy's structure, phase composition, and mechanical and functional properties was studied. It was shown that thermomechanical processing leads to the formation of a nanosubgrained structure (polygonized with subgrains below 100 nm) in the 500-600 °C PDA range, which transforms to a recrystallized structure of β-phase when PDA temperature increases. Simultaneously, the phase composition and the β → α″ transformation kinetics vary. It was found that after conventional cold rolling and PDA, Ti-Nb-Ta alloy manifests superelastic and shape memory behaviors. During aging at 300 °C (1 h), an important quantity of randomly scattered equiaxed ω-precipitates forms, which results in improved superelastic cyclic properties. On the other hand, aging at 300 °C (3 h) changes the ω-precipitates' particle morphology from equiaxed to elongated and leads to their coarsening, which negatively affects the superelastic and shape memory functional properties of Ti-Nb-Ta alloy.

  17. Finite difference calculation of acoustic streaming including the boundary layer phenomena in an ultrasonic air pump on graphics processing unit array

    NASA Astrophysics Data System (ADS)

    Wada, Yuji; Koyama, Daisuke; Nakamura, Kentaro

    2012-09-01

    Direct finite difference fluid simulation of acoustic streaming on the fine-meshed threedimension model by graphics processing unit (GPU)-oriented calculation array is discussed. Airflows due to the acoustic traveling wave are induced when an intense sound field is generated in a gap between a bending transducer and a reflector. Calculation results showed good agreement with the measurements in the pressure distribution. In addition to that, several flow-vortices were observed near the boundary of the reflector and the transducer, which have been often discussed in acoustic tube near the boundary, and have not yet been observed in the calculation in the ultrasonic air pump of this type.

  18. Characterization of process-related impurities including forced degradation products of alogliptin benzoate and the development of the corresponding reversed-phase high-performance liquid chromatography method.

    PubMed

    Zhou, YuXia; Zhou, WenTao; Sun, LiLi; Zou, QiaoGen; Wei, Ping; OuYang, PingKai

    2014-06-01

    The characterization of process-related impurities and forced degradants of alogliptin benzoate (Alb) in bulk drugs and a stability-indicating HPLC method for the separation and quantification of all the impurities were investigated. Alb was found to be unstable under acid and alkali stress conditions and two major degradation products (Imp-F and Imp-G) were observed. The optimum separation was achieved on Kromasil C18 (250 × 4.6 mm, 5 μm) using 0.1% perchloric acid (pH adjusted to 3.0 with triethylamine) and acetonitrile as a mobile phase in gradient mode. The proposed method was found to be stability indicating, precise, linear (0.10-75.0 μg/mL), accurate, sensitive, and robust for the quantitation of Alb and its process-related substances and degradation products. The structures of 11 impurities were characterized and confirmed by NMR spectroscopy, MS, and IR spectroscopy, and the most probable formation mechanisms of all impurities were proposed according to the synthesis route.

  19. Development of a Validated LC Method for Separation of Process-Related Impurities Including the R-Enantiomer of S-Pramipexole on Polysaccharide Chiral Stationary Phases.

    PubMed

    Ramisetti, Nageswara Rao; Kuntamukkala, Ramakrishna; Arnipalli, Manikanta Swamy

    2015-07-01

    Despite the availability of a few methods for individual separation of S-pramipexole from its process-related impurities, no common liquid chromatography (LC) method is reported so far in the literature. The present article describes the development of a single-run LC method for simultaneous determination of S-pramipexole and its enantiomeric and process-related impurities on a Chiralpak AD-H (150 x 4.6 mm, 5μm) column using n-hexane/ethanol/n-butylamine (75:25:0.1 v/v/v) as a mobile phase in an isocratic mode of elution at a flow rate of 1.2 ml/min at 30°C. The chromatographic eluents were monitored at a wavelength of 260 nm using a photodiode array detector. Excellent enantioseparation with good resolutions (Rs ≥ 2.88) and peak shapes (As ≤ 1.21) for all analytes was achieved. The proposed method was validated according to International Conference Harmonization (ICH) guidelines in terms of accuracy, precision, sensitivity, and linearity. Limits of quantification of impurities (0.25-0.55 μg/ml) indicate the highest sensitivity achievable by the proposed method. The method has an advantage of selectivity and suitability for routine determination of not only chiral impurity but also all possible related substances in active pharmaceutical ingredients of S-pramipexole.

  20. Tomato ribonuclease LX with the functional endoplasmic reticulum retention motif HDEF is expressed during programmed cell death processes, including xylem differentiation, germination, and senescence.

    PubMed

    Lehmann, K; Hause, B; Altmann, D; Köck, M

    2001-10-01

    We have studied the subcellular localization of the acid S-like ribonuclease (RNase) LX in tomato (Lycopersicon esculentum Mill.) cells using a combination of biochemical and immunological methods. It was found that the enzyme, unexpectedly excluded from highly purified vacuoles, accumulates in the endoplasmic reticulum. The evidence that RNase LX is a resident of the endoplasmic reticulum (ER) is supported by an independent approach showing that the C-terminal peptide HDEF of RNase LX acts as an alternative ER retention signal in plants. For functional testing, the cellular distribution of chimeric protein constructs based on a marker protein, Brazil nut (Bertholletia excelsa) 2S albumin, was analyzed immunochemically in transgenic tobacco (Nicotiana tabacum) plants. Here, we report that the peptide motif is necessary and sufficient to accumulate 2S albumin constructs of both vacuolar and extracellular final destinations in the ER. We have shown immunochemically that RNase LX is specifically expressed during endosperm mobilization and leaf and flower senescence. Using immunofluorescence, RNase LX protein was detected in immature tracheary elements, suggesting a function in xylem differentiation. These results support a physiological function of RNase LX in selective cell death processes that are also thought to involve programmed cell death. It is assumed that RNase LX accumulates in an ER-derived compartment and is released by membrane disruption into the cytoplasma of those cells that are intended to undergo autolysis. These processes are accompanied by degradation of cellular components supporting a metabolic recycling function of the intracellular RNase LX.

  1. Comparison of pilot and industrial scale atmospheric pressure glow discharge systems including a novel electro-acoustic technique for process monitoring

    NASA Astrophysics Data System (ADS)

    Tynan, J.; Law, V. J.; Ward, P.; Hynes, A. M.; Cullen, J.; Byrne, G.; Daniels, S.; Dowling, D. P.

    2010-02-01

    A comparison of a pilot and industrial scale atmospheric pressure polymer processing plasma system has been carried out using process-monitoring diagnostic tools during treatment of amorphous polyethylene terephthalate. These systems have been compared using optical emission spectroscopy (OES), photodiode (PD) analysis and multi-variate analysis of the applied electrical and emitted electro-acoustic signals to facilitate scale up operations from the pilot to the industrial scale system. The voltage, current, electro-acoustic intensity and frequency of the plasma systems were found to change systematically with an increase in applied plasma power and addition of oxygen (O2) into a helium (He) plasma. The plasma drive frequency was pulled by the plasma reactance from approximately 26 to 16 kHz on the pilot system and from approximately 36 to 32 kHz on the industrial system, for an increase in applied plasma power and addition of O2. The OES analysis revealed a number of peaks associated with nitrogen (N2) species between 250 and 450 nm due to the presence of air within the He plasma. Temporally resolved analysis of the discharge emission carried out using a PD showed an increase in the number of discharge events per power cycle with an increase in power and a decrease in emission intensity for addition of O2 into the He plasma for both the pilot and industrial scale systems. Using these diagnostic tools both plasma stability and run to run variations were assessed. A visual analysis of the 1.2 m wide plasma was also carried out where a more homogeneous plasma was observed at higher powers.

  2. Adaptation of land-use demands to the impact of climate change on the hydrological processes of an urbanized watershed.

    PubMed

    Lin, Yu-Pin; Hong, Nien-Ming; Chiang, Li-Chi; Liu, Yen-Lan; Chu, Hone-Jay

    2012-11-12

    The adaptation of land-use patterns is an essential aspect of minimizing the inevitable impact of climate change at regional and local scales; for example, adapting watershed land-use patterns to mitigate the impact of climate change on a region's hydrology. The objective of this study is to simulate and assess a region's ability to adapt to hydrological changes by modifying land-use patterns in the Wu-Du watershed in northern Taiwan. A hydrological GWLF (Generalized Watershed Loading Functions) model is used to simulate three hydrological components, namely, runoff, groundwater and streamflow, based on various land-use scenarios under six global climate models. The land-use allocations are simulated by the CLUE-s model for the various development scenarios. The simulation results show that runoff and streamflow are strongly related to the precipitation levels predicted by different global climate models for the wet and dry seasons, but groundwater cycles are more related to land-use. The effects of climate change on groundwater and runoff can be mitigated by modifying current land-use patterns; and slowing the rate of urbanization would also reduce the impact of climate change on hydrological components. Thus, land-use adaptation on a local/regional scale provides an alternative way to reduce the impacts of global climate change on local hydrology.

  3. Porcine Epidemic Diarrhea Virus 3C-Like Protease-Mediated Nucleocapsid Processing: Possible Link to Viral Cell Culture Adaptability.

    PubMed

    Jaru-Ampornpan, Peera; Jengarn, Juggragarn; Wanitchang, Asawin; Jongkaewwattana, Anan

    2017-01-15

    Porcine epidemic diarrhea virus (PEDV) causes severe diarrhea and high mortality rates in newborn piglets, leading to massive losses to the swine industry worldwide during recent epidemics. Intense research efforts are now focusing on defining viral characteristics that confer a growth advantage, pathogenicity, or cell adaptability in order to better understand the PEDV life cycle and identify suitable targets for antiviral or vaccine development. Here, we report a unique phenomenon of PEDV nucleocapsid (N) cleavage by the PEDV-encoded 3C-like protease (3Cpro) during infection. The identification of the 3Cpro cleavage site at the C terminus of N supported previous observations that PEDV 3Cpro showed a substrate requirement slightly different from that of severe acute respiratory syndrome coronavirus (SARS-CoV) 3Cpro and revealed a greater flexibility in its substrate recognition site. This cleavage motif is present in the majority of cell culture-adapted PEDV strains but is missing in emerging field isolates. Remarkably, reverse-genetics-derived cell culture-adapted PEDVAVCT12 harboring uncleavable N displayed growth retardation in Vero E6-APN cells compared to the wild-type virus. These observations altogether shed new light on the investigation and characterization of the PEDV nucleocapsid protein and its possible link to cell culture adaptation.

  4. The Cultural Adaptation Process of Agricultural and Life Sciences Students on Short-Term Study Abroad Experiences

    ERIC Educational Resources Information Center

    Conner, Nathan William

    2013-01-01

    The purpose of this study was to explore how undergraduate students in a college of agricultural and life sciences experienced cultural adaptation during short-term study abroad programs. The specific objectives of this study were to describe how undergraduate students in the college of agricultural and life sciences experienced culture throughout…

  5. Methods of Psychological and Pedagogical Accompaniment of First-Year Students in Process of Adapting to Learning at University

    ERIC Educational Resources Information Center

    Maralova, Tatyana P.; Filipenkova, Olesya G.; Galitskikh, Elena O.; Shulga, Tatiana I.; Sidyacheva, Natalya V.; Ovsyanik, Olga A.

    2016-01-01

    The relevance of the study is conditioned by the complexity of students' adaptation to learning at University due to the change of social environment, an alarming feelings about the precise self-determination, lack of knowledge in opportunities for self-expression in art, science, sport and public life. The purpose of the paper is to identify…

  6. KnowledgePuzzle: A Browsing Tool to Adapt the Web Navigation Process to the Learner's Mental Model

    ERIC Educational Resources Information Center

    AlAgha, Iyad

    2012-01-01

    This article presents KnowledgePuzzle, a browsing tool for knowledge construction from the web. It aims to adapt the structure of web content to the learner's information needs regardless of how the web content is originally delivered. Learners are provided with a meta-cognitive space (e.g., a concept mapping tool) that enables them to plan…

  7. COASP and CHASP Processors for Strip-map and Moving Target Adaptive Processing of EC CV-580 Synthetic Aperture Radar Data: Algorithms and Software Description

    DTIC Science & Technology

    2006-05-01

    synthetic aperture radar ( SAR ) since the late 1990’s in support of target detection and classification studies. Until recently, processing of data from...this SAR system has been carried out in-house using the Polarimetrc Generalized Airborne SAR Processor (PolGASP) that was developed at the Canada...COASP (Configurable Airborne SAR Processor) and CHASP (Chip Adaptive SAR Processor) processors have been developed to replace and augment PolGASP and

  8. The importance of including conductivity and dielectric permittivity information when processing low-frequency GPR and high-frequency EMI data sets

    NASA Astrophysics Data System (ADS)

    Hatch, Michael A.; Heinson, Graham; Munday, Tim; Thiel, Stephan; Lawrie, Ken; Clarke, Jonathan D. A.; Mill, Philip

    2013-09-01

    The full solution for the wavenumber equation in electromagnetic (EM) theory is available, but not routinely used when processing ground penetrating radar (GPR), and electromagnetic induction (EMI) data. The wavenumber approach is important as it is used for the development of concepts such as skin depth and phase velocity, as well as being the basis for more complete interpretation of EM data sets. Approximations that make the solution simpler are common, and sufficiently accurate, provided that the underlying assumptions are not grossly violated. With the advent of lower-frequency GPR systems (25 MHz and below) and higher-frequency EMI systems (greater than 100 kHz) such approximations need to be re-examined. This paper reviews the full wavenumber expression and then compares phase velocity and skin depth equations based on approximations with the equations for the same parameter based on the full solution. This comparison allows the conditions under which the assumptions are valid to be refined. In this paper it is shown that for GPR surveys conducted under transition band conditions, the error in phase velocity estimates based on low-loss assumptions may be 40%. Similarly, for EMI surveys the skin depth estimation errors may be more than 30% when the equation based on quasi-static assumptions is used instead of the full solution.

  9. Dummy-surface molecularly imprinted polymers on magnetic graphene oxide for rapid and selective quantification of acrylamide in heat-processed (including fried) foods.

    PubMed

    Ning, Fangjian; Qiu, Tingting; Wang, Qi; Peng, Hailong; Li, Yanbin; Wu, Xiaqing; Zhang, Zhong; Chen, Linxin; Xiong, Hua

    2017-04-15

    Novel nano-sized dummy-surface molecularly imprinted polymers (DSMIPs) on a magnetic graphene oxide (GO-Fe3O4) surface were developed as substrates, using propionamide as a dummy template molecule for the selective recognition and rapid pre-concentration and removal of acrylamide (AM) from food samples. These products showed rapid kinetics, high binding capacity (adsorption at 3.68mg·g(-1)), and selectivity (imprinting factor α 2.83); the adsorption processes followed the Langmuir-Freundlich isotherm and pseudo-second-order kinetic models. Excellent recognition selectivity toward acrylamide was achieved compared to structural analogs, such as propionic and acrylic acids (selectivity factor β 2.33, and 2.20, respectively). Moreover, DSMIPs-GO-Fe3O4 was used to quantify acrylamide in food samples, yielding satisfactory recovery (86.7-94.3%) and low relative standard deviation (<4.85%). Thus, our DSMIPs-GO-Fe3O4-based procedure was demonstrated to be a convenient and practical method for the separation, enrichment, and removal of acrylamide from food samples.

  10. Adaptive sampler

    DOEpatents

    Watson, B.L.; Aeby, I.

    1980-08-26

    An adaptive data compression device for compressing data is described. The device has a frequency content, including a plurality of digital filters for analyzing the content of the data over a plurality of frequency regions, a memory, and a control logic circuit for generating a variable rate memory clock corresponding to the analyzed frequency content of the data in the frequency region and for clocking the data into the memory in response to the variable rate memory clock.

  11. Prediction of individual milk proteins including free amino acids in bovine milk using mid-infrared spectroscopy and their correlations with milk processing characteristics.

    PubMed

    McDermott, A; Visentin, G; De Marchi, M; Berry, D P; Fenelon, M A; O'Connor, P M; Kenny, O A; McParland, S

    2016-04-01

    -infrared spectroscopy predictions (0.95). Weaker correlations among FAA were observed than the correlations among the protein fractions. Pearson correlations between gold standard protein fractions and the milk processing characteristics of rennet coagulation time, curd firming time, curd firmness, heat coagulating time, pH, and casein micelle size were weak to moderate and ranged from -0.48 (protein and pH) to 0.50 (total casein and a30). Pearson correlations between gold standard FAA and these milk processing characteristics were also weak to moderate and ranged from -0.60 (Val and pH) to 0.49 (Val and K20). Results from this study indicate that mid-infrared spectroscopy has the potential to predict protein fractions and some FAA in milk at a population level.

  12. Streamflow and water-quality conditions including geologic sources and processes affecting selenium loading in the Toll Gate Creek watershed, Aurora, Arapahoe County, Colorado, 2007

    USGS Publications Warehouse

    Paschke, Suzanne S.; Runkel, Robert L.; Walton-Day, Katherine; Kimball, Briant A.; Schaffrath, Keelin R.

    2013-01-01

    Toll Gate Creek is a perennial stream draining a suburban area in Aurora, Colorado, where selenium concentrations have consistently exceeded the State of Colorado aquatic-life standard for selenium of 4.6 micrograms per liter since the early 2000s. In cooperation with the City of Aurora, Colorado, Utilities Department, a synoptic water-quality study was performed along an 18-kilometer reach of Toll Gate Creek extending from downstream from Quincy Reservoir to the confluence with Sand Creek to develop a detailed understanding of streamflow and concentrations and loads of selenium in Toll Gate Creek. Streamflow and surface-water quality were characterized for summer low-flow conditions (July–August 2007) using four spatially overlapping synoptic-sampling subreaches. Mass-balance methods were applied to the synoptic-sampling and tracer-injection results to estimate streamflow and develop spatial profiles of concentration and load for selenium and other chemical constituents in Toll Gate Creek surface water. Concurrent groundwater sampling determined concentrations of selenium and other chemical constituents in groundwater in areas surrounding the Toll Gate Creek study reaches. Multivariate principal-component analysis was used to group samples and to suggest common sources for dissolved selenium and major ions. Hydrogen and oxygen stable-isotope ratios, groundwater-age interpretations, and chemical analysis of water-soluble paste extractions from core samples are presented, and interpretation of the hydrologic and geochemical data support conclusions regarding geologic sources of selenium and the processes affecting selenium loading in the Toll Gate Creek watershed.

  13. Population genetic analyses of Hypoplectrus coral reef fishes provide evidence that local processes are operating during the early stages of marine adaptive radiations.

    PubMed

    Puebla, Oscar; Bermingham, Eldredge; Guichard, Frédéric

    2008-03-01

    Large-scale, spatially explicit models of adaptive radiation suggest that the spatial genetic structure within a species sampled early in the evolutionary history of an adaptive radiation might be higher than the genetic differentiation between different species formed during the same radiation over all locations. Here we test this hypothesis with a spatial population genetic analysis of Hypoplectrus coral reef fishes (Serranidae), one of the few potential cases of a recent adaptive radiation documented in the marine realm. Microsatellite analyses of Hypoplectrus puella (barred hamlet) and Hypoplectrus nigricans (black hamlet) from Belize, Panama and Barbados validate the population genetic predictions at the regional scale for H. nigricans despite the potential for high levels of gene flow between populations resulting from the 3-week planktonic larval phase of Hypoplectrus. The results are different for H. puella, which is characterized by significantly lower levels of spatial genetic structure than H. nigricans. An extensive field survey of Hypoplectrus population densities complemented by individual-based simulations shows that the higher abundance and more continuous distribution of H. puella could account for the reduced spatial genetic structure within this species. The genetic and demographic data are also consistent with the hypothesis that H. puella might represent the ancestral form of the Hypoplectrus radiation, and that H. nigricans might have evolved repeatedly from H. puella through ecological speciation. Altogether, spatial genetic analysis within and between Hypoplectrus species indicate that local processes can operate at a regional scale within recent marine adaptive radiations.

  14. Memory distortion: an adaptive perspective

    PubMed Central

    Schacter, Daniel L.; Guerin, Scott A.; St. Jacques, Peggy L.

    2011-01-01

    Memory is prone to distortions that can have serious consequences in everyday life. Here we integrate emerging evidence that several types of memory distortions – imagination inflation, gist-based and associative memory errors, and post-event misinformation – reflect adaptive cognitive processes that contribute to the efficient functioning of memory, but produce distortions as a consequence of doing so. We consider recent cognitive and neuroimaging studies that link these distortions with adaptive processes, including simulation of future events, semantic and contextual encoding, creativity, and memory updating. We also discuss new evidence concerning factors that can influence the occurrence of memory distortions, such as sleep and retrieval conditions, as well as conceptual issues related to the development of an adaptive perspective. PMID:21908231

  15. NEEDS - Information Adaptive System

    NASA Technical Reports Server (NTRS)

    Kelly, W. L.; Benz, H. F.; Meredith, B. D.

    1980-01-01

    The Information Adaptive System (IAS) is an element of the NASA End-to-End Data System (NEEDS) Phase II and is focused toward onboard image processing. The IAS is a data preprocessing system which is closely coupled to the sensor system. Some of the functions planned for the IAS include sensor response nonuniformity correction, geometric correction, data set selection, data formatting, packetization, and adaptive system control. The inclusion of these sensor data preprocessing functions onboard the spacecraft will significantly improve the extraction of information from the sensor data in a timely and cost effective manner, and provide the opportunity to design sensor systems which can be reconfigured in near real-time for optimum performance. The purpose of this paper is to present the preliminary design of the IAS and the plans for its development.

  16. Development of mathematical models to elaborate strategies, select alternatives and development of plans for adaptation of communities to climate change in different geographical areas including costs to implement it

    NASA Astrophysics Data System (ADS)

    Anton, J. M.; Grau, J. B.; Tarquis, A. M.; Andina, D.; Cisneros, J. M.

    2012-04-01

    There is evidence that the climate changes and that now, the change is influenced and accelerated by the CO2 augmentation in atmosphere due to combustion by humans. Such "Climate change" is on the policy agenda at the global level, with the aim of understanding and reducing its causes and to mitigate its consequences. In most countries and international organisms UNO (e.g. Rio de Janeiro 1992), OECD, EC, etc … the efforts and debates have been directed to know the possible causes, to predict the future evolution of some variable conditioners, and trying to make studies to fight against the effects or to delay the negative evolution of such. The Protocol of Kyoto 1997 set international efforts about CO2 emissions, but it was partial and not followed e.g. by USA and China …, and in Durban 2011 the ineffectiveness of humanity on such global real challenges was set as evident. Among all that, the elaboration of a global model was not boarded that can help to choose the best alternative between the feasible ones, to elaborate the strategies and to evaluate the costs, and the authors propose to enter in that frame for study. As in all natural, technological and social changes, the best-prepared countries will have the best bear and the more rapid recover. In all the geographic areas the alternative will not be the same one, but the model must help us to make the appropriated decision. It is essential to know those areas that are more sensitive to the negative effects of climate change, the parameters to take into account for its evaluation, and comprehensive plans to deal with it. The objective of this paper is to elaborate a mathematical model support of decisions, which will allow to develop and to evaluate alternatives of adaptation to the climatic change of different communities in Europe and Latin-America, mainly in especially vulnerable areas to the climatic change, considering in them all the intervening factors. The models will consider criteria of physical

  17. Connector adapter

    NASA Technical Reports Server (NTRS)

    Hacker, Scott C. (Inventor); Dean, Richard J. (Inventor); Burge, Scott W. (Inventor); Dartez, Toby W. (Inventor)

    2007-01-01

    An adapter for installing a connector to a terminal post, wherein the connector is attached to a cable, is presented. In an embodiment, the adapter is comprised of an elongated collet member having a longitudinal axis comprised of a first collet member end, a second collet member end, an outer collet member surface, and an inner collet member surface. The inner collet member surface at the first collet member end is used to engage the connector. The outer collet member surface at the first collet member end is tapered for a predetermined first length at a predetermined taper angle. The collet includes a longitudinal slot that extends along the longitudinal axis initiating at the first collet member end for a predetermined second length. The first collet member end is formed of a predetermined number of sections segregated by a predetermined number of channels and the longitudinal slot.

  18. Expressing Adaptation Strategies Using Adaptation Patterns

    ERIC Educational Resources Information Center

    Zemirline, N.; Bourda, Y.; Reynaud, C.

    2012-01-01

    Today, there is a real challenge to enable personalized access to information. Several systems have been proposed to address this challenge including Adaptive Hypermedia Systems (AHSs). However, the specification of adaptation strategies remains a difficult task for creators of such systems. In this paper, we consider the problem of the definition…

  19. Adaptation in Distance Education--New Experiences from Networking Universities in Germany.

    ERIC Educational Resources Information Center

    Bernath, Ulrich; Fichten, Wolfgang

    1999-01-01

    Describes a nurses' training program in Germany that adapted self-instructional learning material for use by networked universities for distance education. Topics include testing, evaluation, and revision of the learning modules; adaptation in distance education; and empirical evidence for the process of adaptation. (LRW)

  20. The specificity of neural responses to music and their relation to voice processing: an fMRI-adaptation study.

    PubMed

    Armony, Jorge L; Aubé, William; Angulo-Perkins, Arafat; Peretz, Isabelle; Concha, Luis

    2015-04-23

    Several studies have identified, using functional magnetic resonance imaging (fMRI), a region within the superior temporal gyrus that preferentially responds to musical stimuli. However, in most cases, significant responses to other complex stimuli, particularly human voice, were also observed. Thus, it remains unknown if the same neurons respond to both stimulus types, albeit with different strengths, or whether the responses observed with fMRI are generated by distinct, overlapping neural populations. To address this question, we conducted an fMRI experiment in which short music excerpts and human vocalizations were presented in a pseudo-random order. Critically, we performed an adaptation-based analysis in which responses to the stimuli were analyzed taking into account the category of the preceding stimulus. Our results confirm the presence of a region in the anterior STG that responds more strongly to music than voice. Moreover, we found a music-specific adaptation effect in this area, consistent with the existence of music-preferred neurons. Lack of differences between musicians and non-musicians argues against an expertise effect. These findings provide further support for neural separability between music and speech within the temporal lobe.