CFD Based Added Mass Prediction in Cruise Condition of Underwater Vehicle Dynamic

NASA Astrophysics Data System (ADS)

Agoes Moelyadi, Mochammad; Bambang Riswandi, Bagus

2018-04-01

One of the unsteady flow behavior on the hydrodynamic characteristics of underwater vehicle is the presence of added mass. In cruising conditions, the underwater vehicle may require the addition of speed or experience the disturbance in the form of unsteady flow so that cause the hydrodynamic interaction between the surface of the vehicle with the surrounding fluid. This leads to the rise of local velocity of flow and the great changes of hydrodynamic forces which are very influential on the stability of the underwater vehicle. One of the result is an additional force called added mass. It is very useful parameter to control underwater vehicle dynamic.This paper reports the research on the added mass coefficient of underwater vehicles obtained through the Computational Fluid Dynmaic (CFD) simulation method using CFX software. Added mass coefficient is calculated by performing an unsteady simulation or known as transient simulation. Computational simulations are based on the Reynold Average Navier- Stokes (RANS) equation solution. The simulated vehicle moves forward and backward according to the sinus function, with a frequency of 0.25 Hz, a 2 m amplitude, a cruising depth of 10 m below sea level, and Vcruise 1.54 m / s (Re = 9.000.000). Simulation result data includes velocity contour, variation of force and acceleration to frequency, and added mass coefficient.

Preventing Fusion Mass Shift Avoids Postoperative Distal Curve Adding-on in Adolescent Idiopathic Scoliosis.

PubMed

Shigematsu, Hideki; Cheung, Jason Pui Yin; Bruzzone, Mauro; Matsumori, Hiroaki; Mak, Kin-Cheung; Samartzis, Dino; Luk, Keith Dip Kei

2017-05-01

Surgery for adolescent idiopathic scoliosis (AIS) is only complete after achieving fusion to maintain the correction obtained intraoperatively. The instrumented or fused segments can be referred to as the "fusion mass". In patients with AIS, the ideal fusion mass strategy has been established based on fulcrum-bending radiographs for main thoracic curves. Ideally, the fusion mass should achieve parallel endplates of the upper and lower instrumented vertebra and correct any "shift" for truncal balance. Distal adding-on is an important element to consider in AIS surgery. This phenomenon represents a progressive increase in the number of vertebrae included distally in the primary curvature and it should be avoided as it is associated with unsatisfactory cosmesis and an increased risk of revision surgery. However, it remains unknown whether any fusion mass shift, or shift in the fusion mass or instrumented segments, affects global spinal balance and distal adding-on after curve correction surgery in patients with AIS. (1) To investigate the relationship among postoperative fusion mass shift, global balance, and distal adding-on phenomenon in patients with AIS; and (2) to identify a cutoff value of fusion mass shift that will lead to distal adding-on. This was a retrospective study of patients with AIS from a single institution. Between 2006 and 2011 we performed 69 selective thoracic fusions for patients with main thoracic AIS. All patients were evaluated preoperatively and at 2 years postoperatively. The Cobb angle between the cranial and caudal endplates of the fusion mass and the coronal shift between them, which was defined as "fusion mass shift", were measured. Patients with a fusion mass Cobb angle greater than 20° were excluded to specifically determine the effect of fusion mass shift on distal adding-on phenomenon. Fusion mass shift was empirically set as 20 mm for analysis. Therefore, of the 69 patients who underwent selective thoracic fusion, only 52 with a

AdS5×S(5) mirror model as a string sigma model.

PubMed

Arutyunov, Gleb; van Tongeren, Stijn J

2014-12-31

Doing a double Wick rotation in the world sheet theory of the light cone AdS5×S(5) superstring results in an inequivalent, so-called mirror theory that plays a central role in the field of integrability in the AdS-CFT correspondence. We show that this mirror theory can be interpreted as the light cone theory of a free string on a different background. This background is related to dS5×H(5) by a double T-duality, and has hidden supersymmetry. The geometry can also be extracted from an integrable deformation of the AdS5×S(5) sigma model, and we prove the observed mirror duality of these deformed models at the bosonic level as a byproduct. While we focus on AdS5×S(5), our results apply more generally.

Between simplicity and accuracy: Effect of adding modeling details on quarter vehicle model accuracy.

PubMed

Soong, Ming Foong; Ramli, Rahizar; Saifizul, Ahmad

2017-01-01

Quarter vehicle model is the simplest representation of a vehicle that belongs to lumped-mass vehicle models. It is widely used in vehicle and suspension analyses, particularly those related to ride dynamics. However, as much as its common adoption, it is also commonly accepted without quantification that this model is not as accurate as many higher-degree-of-freedom models due to its simplicity and limited degrees of freedom. This study investigates the trade-off between simplicity and accuracy within the context of quarter vehicle model by determining the effect of adding various modeling details on model accuracy. In the study, road input detail, tire detail, suspension stiffness detail and suspension damping detail were factored in, and several enhanced models were compared to the base model to assess the significance of these details. The results clearly indicated that these details do have effect on simulated vehicle response, but to various extents. In particular, road input detail and suspension damping detail have the most significance and are worth being added to quarter vehicle model, as the inclusion of these details changed the response quite fundamentally. Overall, when it comes to lumped-mass vehicle modeling, it is reasonable to say that model accuracy depends not just on the number of degrees of freedom employed, but also on the contributions from various modeling details.

Between simplicity and accuracy: Effect of adding modeling details on quarter vehicle model accuracy

PubMed Central

2017-01-01

Quarter vehicle model is the simplest representation of a vehicle that belongs to lumped-mass vehicle models. It is widely used in vehicle and suspension analyses, particularly those related to ride dynamics. However, as much as its common adoption, it is also commonly accepted without quantification that this model is not as accurate as many higher-degree-of-freedom models due to its simplicity and limited degrees of freedom. This study investigates the trade-off between simplicity and accuracy within the context of quarter vehicle model by determining the effect of adding various modeling details on model accuracy. In the study, road input detail, tire detail, suspension stiffness detail and suspension damping detail were factored in, and several enhanced models were compared to the base model to assess the significance of these details. The results clearly indicated that these details do have effect on simulated vehicle response, but to various extents. In particular, road input detail and suspension damping detail have the most significance and are worth being added to quarter vehicle model, as the inclusion of these details changed the response quite fundamentally. Overall, when it comes to lumped-mass vehicle modeling, it is reasonable to say that model accuracy depends not just on the number of degrees of freedom employed, but also on the contributions from various modeling details. PMID:28617819

Ad-Hoc Networks and the Mobile Application Security System (MASS)

DTIC Science & Technology

2006-01-01

solution to this problem that addresses critical aspects of security in ad-hoc mobile application networks. This approach involves preventing unauthorized...modification of a mobile application , both by other applications and by hosts, and ensuring that mobile code is authentic and authorized. These...capabilities constitute the Mobile Application Security System (MASS). The MASS applies effective, robust security to mobile application -based systems

Resistive thrust production can be as crucial as added mass mechanisms for inertial undulatory swimmers

NASA Astrophysics Data System (ADS)

Piñeirua, M.; Godoy-Diana, R.; Thiria, B.

2015-08-01

In this Rapid Communication, we address a crucial point regarding the description of moderate to high Reynolds numbers aquatic swimmers. For decades, swimming animals have been classified in two different families of propulsive mechanisms based on the Reynolds number: the resistive swimmers, using local friction to produce the necessary thrust force for locomotion at low Reynolds number, and the reactive swimmers, lying in the high Reynolds range, and using added mass acceleration (described by perfect fluid theory). However, inertial swimmers are also systems that dissipate energy, due to their finite size, therefore involving strong resistive contributions, even for high Reynolds numbers. Using a complete model for the hydrodynamic forces, involving both reactive and resistive contributions, we revisit here the physical mechanisms responsible for the thrust production of such swimmers. We show, for instance, that the resistive part of the force balance is as crucial as added mass effects in the modeling of the thrust force, especially for elongated species. The conclusions brought by this work may have significant contributions to the understanding of complex swimming mechanisms, especially for the future design of artificial swimmers.

Study of micro piezoelectric vibration generator with added mass and capacitance suitable for broadband vibration

DOE Office of Scientific and Technical Information (OSTI.GOV)

He, Qing, E-mail: hqng@163.com; Mao, Xinhua, E-mail: 30400414@qq.com; Chu, Dongliang, E-mail: 569256386@qq.com

This study proposes an optimized frequency adjustment method that uses a micro-cantilever beam-based piezoelectric vibration generator based on a combination of added mass and capacitance. The most important concept of the proposed method is that the frequency adjustment process is divided into two steps: the first is a rough adjustment step that changes the size of the mass added at the end of cantilever to adjust the frequency in a large-scale and discontinuous manner; the second step is a continuous but short-range frequency adjustment via the adjustable added capacitance. Experimental results show that when the initial natural frequency of amore » micro piezoelectric vibration generator is 69.8 Hz, then this natural frequency can be adjusted to any value in the range from 54.2 Hz to 42.1 Hz using the combination of the added mass and the capacitance. This method simply and effectively matches a piezoelectric vibration generator’s natural frequency to the vibration source frequency.« less

Effect of added mass on treadmill performance and pulmonary function.

PubMed

Walker, Rachel E; Swain, David P; Ringleb, Stacie I; Colberg, Sheri R

2015-04-01

Military personnel engage in strenuous physical activity and load carriage. This study evaluated the role of body mass and of added mass on aerobic performance (uphill treadmill exercise) and pulmonary function. Performance on a traditional unloaded run test (4.8 km) was compared with performance on loaded tasks. Subjects performed an outdoor 4.8-km run and 4 maximal treadmill tests wearing loads of 0, 10, 20, and 30 kg. Subjects' pulmonary function (forced expired volume in 1 second [FEV1], forced vital capacity [FVC], and maximal voluntary ventilation [MVV]) was tested with each load, and peak values of heart rate, oxygen consumption ((Equation is included in full-text article.)), ventilation (VE), and respiratory exchange ratio (RER) were measured during each treadmill test. Performance on the 4.8-km run was correlated with treadmill performance, measured as time to exhaustion (TTE), with the strength of the correlation decreasing with load (r = 0.87 for 0 kg to 0.76 for 30 kg). Body mass was not correlated with TTE, other than among men with the 30-kg load (r = 0.48). During treadmill exercise, all peak responses other than RER decreased with load. Pulmonary function measures (FEV1, FVC, and MVV) decreased with load. Body mass was poorly correlated with treadmill performance, but added mass decreased performance. The decreased performance may be in part because of decreased pulmonary function. Unloaded 4.8-km run performance was correlated to unloaded uphill treadmill performance, but less so as load increased. Therefore, traditional run tests may not be an effective means of evaluating aerobic performance for military field operations.

The Influence of Added Mass on Optimal Step Length in Running.

PubMed

Reenalda, Jasper; Maas, Maurice T F; de Koning, Jos J

2016-10-01

To examine the influence of induced changes in the morphology of the leg by adding mass on the optimal step length (OSL) in experienced runners to get more insight into parameters that influence preferred step length (PSL) and OSL. Thirteen experienced male runners (mean age 26.9 ± 6.1 y, height 183.7 ± 7.1 cm, mass 71.8 ± 5.9 kg) ran on a treadmill in 3 different conditions: unloaded (UL), loaded with 2 kg mass at the ankles (MA), and loaded with 2 kg mass at the hips (MH) at 7 different step lengths (SLs). SL deviations were expressed as deviations in relative leg length (%LL) from the individual PSL: 0%LL, ±5%LL, ±10%LL, and ±15%LL. Trials lasted 8 min, and 8 min of rest was given between trials. Oxygen uptake (V̇O 2 ) was expressed as a fraction of V̇O 2 at PSL + 0%LL in the unloaded condition (%V̇O 2 ). The %SL with the lowest value of %V̇O 2 was considered the OSL for this group of participants. OSL at the UL condition was 6% shorter than PSL. The MA condition resulted in a 7%LL larger OSL than at UL and MH (P < .05). The mass distribution of the leg is a determinant of the OSL. As a consequence of the added mass to the ankles, OSL was 7%LL longer. Morphological characteristics of the leg might therefore play an important role in determining the runner's individual optimal SL.

AdS black disk model for small-x DIS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cornalba, Lorenzo; Costa, Miguel S.; Penedones, Joao

2011-05-23

Using the approximate conformal invariance of QCD at high energies we consider a simple AdS black disk model to describe saturation in DIS. Deep inside saturation the structure functions have the same power law scaling, F{sub T}{approx}F{sub L}{approx}{sup -}{omega}, where {omega} is related to the expansion rate of the black disk with energy. Furthermore, the ratio F{sub L}/F{sub T} is given by the universal value (1+{omega}/3+{omega}), independently of the target.

Supergravity backgrounds for deformations of AdS n × S n supercoset string models

DOE PAGES

Lunin, O.; Roiban, R.; Tseytlin, A. A.

2014-12-11

We considermore » type IIB supergravity backgrounds corresponding to the deformed AdS n × S n × T 10 - 2 n supercoset string models of the type constructed in arXiv:1309.5850[2] which depend on one deformation parameter κ. In AdS 2 × S 2 case we find that the deformed metric can be extended to a full supergravity solution with non-trivial dilaton, RR scalar and RR 5-form strength. The solution depends on a free parameter a that should be chosen as a particular function of κ to correspond to the deformed supercoset model. In AdS 3 × S 3 case the full solution supported by the dilaton, RR scalar and RR 3-form strength exists only in the two special cases, a = 0 and a = 1 . We conjecture that there may be a more general one-parameter solution supported by several RR fields that for particular a = a ( κ ) corresponds to the supercoset model. In the most complicated deformed AdS 5 × S 5 case we were able to find only the expressions for the dilaton and the RR scalar. The full solution is likely to be supported by a combination of the 5-form and 3-form field strengths. We comment on the singularity structure of the resulting metric and exact dilaton field.« less

Supergravity backgrounds for deformations of AdS n × S n supercoset string models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lunin, O.; Roiban, R.; Tseytlin, A. A.

We considermore » type IIB supergravity backgrounds corresponding to the deformed AdS n × S n × T 10 - 2 n supercoset string models of the type constructed in arXiv:1309.5850[2] which depend on one deformation parameter κ. In AdS 2 × S 2 case we find that the deformed metric can be extended to a full supergravity solution with non-trivial dilaton, RR scalar and RR 5-form strength. The solution depends on a free parameter a that should be chosen as a particular function of κ to correspond to the deformed supercoset model. In AdS 3 × S 3 case the full solution supported by the dilaton, RR scalar and RR 3-form strength exists only in the two special cases, a = 0 and a = 1 . We conjecture that there may be a more general one-parameter solution supported by several RR fields that for particular a = a ( κ ) corresponds to the supercoset model. In the most complicated deformed AdS 5 × S 5 case we were able to find only the expressions for the dilaton and the RR scalar. The full solution is likely to be supported by a combination of the 5-form and 3-form field strengths. We comment on the singularity structure of the resulting metric and exact dilaton field.« less

Fermion masses and mixing in general warped extra dimensional models

NASA Astrophysics Data System (ADS)

Frank, Mariana; Hamzaoui, Cherif; Pourtolami, Nima; Toharia, Manuel

2015-06-01

We analyze fermion masses and mixing in a general warped extra dimensional model, where all the Standard Model (SM) fields, including the Higgs, are allowed to propagate in the bulk. In this context, a slightly broken flavor symmetry imposed universally on all fermion fields, without distinction, can generate the full flavor structure of the SM, including quarks, charged leptons and neutrinos. For quarks and charged leptons, the exponential sensitivity of their wave functions to small flavor breaking effects yield hierarchical masses and mixing as it is usual in warped models with fermions in the bulk. In the neutrino sector, the exponential wave-function factors can be flavor blind and thus insensitive to the small flavor symmetry breaking effects, directly linking their masses and mixing angles to the flavor symmetric structure of the five-dimensional neutrino Yukawa couplings. The Higgs must be localized in the bulk and the model is more successful in generalized warped scenarios where the metric background solution is different than five-dimensional anti-de Sitter (AdS5 ). We study these features in two simple frameworks, flavor complimentarity and flavor democracy, which provide specific predictions and correlations between quarks and leptons, testable as more precise data in the neutrino sector becomes available.

Feasibility study of a wearable exoskeleton for children: is the gait altered by adding masses on lower limbs?

PubMed

Rossi, Stefano; Colazza, Alessandra; Petrarca, Maurizio; Castelli, Enrico; Cappa, Paolo; Krebs, Hermano Igo

2013-01-01

We are designing a pediatric exoskeletal ankle robot (pediatric Anklebot) to promote gait habilitation in children with Cerebral Palsy (CP). Few studies have evaluated how much or whether the unilateral loading of a wearable exoskeleton may have the unwanted effect of altering significantly the gait. The purpose of this study was to evaluate whether adding masses up to 2.5 kg, the estimated overall added mass of the mentioned device, at the knee level alters the gait kinematics. Ten healthy children and eight children with CP, with light or mild gait impairment, walked wearing a knee brace with several masses. Gait parameters and lower-limb joint kinematics were analyzed with an optoelectronic system under six conditions: without brace (natural gait) and with masses placed at the knee level (0.5, 1.0, 1.5, 2.0, 2.5 kg). T-tests and repeated measures ANOVA tests were conducted in order to find noteworthy differences among the trial conditions and between loaded and unloaded legs. No statistically significant differences in gait parameters for both healthy children and children with CP were observed in the five "with added mass" conditions. We found significant differences among "natural gait" and "with added masses" conditions in knee flexion and hip extension angles for healthy children and in knee flexion angle for children with CP. This result can be interpreted as an effect of the mechanical constraint induced by the knee brace rather than the effect associated with load increase. The study demonstrates that the mechanical constraint induced by the brace has a measurable effect on the gait of healthy children and children with CP and that the added mass up to 2.5 kg does not alter the lower limb kinematics. This suggests that wearable devices weighing 25 N or less will not noticeably modify the gait patterns of the population examined here.

A note on physical mass and the thermodynamics of AdS-Kerr black holes

DOE Office of Scientific and Technical Information (OSTI.GOV)

McInnes, Brett; Ong, Yen Chin, E-mail: matmcinn@nus.edu.sg, E-mail: yenchin.ong@nordita.org

As with any black hole, asymptotically anti-de Sitter Kerr black holes are described by a small number of parameters, including a ''mass parameter'' M that reduces to the AdS-Schwarzschild mass in the limit of vanishing angular momentum. In sharp contrast to the asymptotically flat case, the horizon area of such a black hole increases with the angular momentum parameter a if one fixes M; this appears to mean that the Penrose process in this case would violate the Second Law of black hole thermodynamics. We show that the correct procedure is to fix not M but rather the ''physical'' massmore » E=M/(1−a{sup 2}/L{sup 2}){sup 2}; this is motivated by the First Law. For then the horizon area decreases with a. We recommend that E always be used as the mass in physical processes: for example, in attempts to ''over-spin'' AdS-Kerr black holes.« less

Lumped mass model of a 1D metastructure for vibration suppression with no additional mass

NASA Astrophysics Data System (ADS)

Reichl, Katherine K.; Inman, Daniel J.

2017-09-01

The article examines the effectiveness of metastructures for vibration suppression from a weight standpoint. Metastructures, a metamaterial inspired concept, are structures with distributed vibration absorbers. In automotive and aerospace industries, it is critical to have low levels of vibrations while also using lightweight materials. Previous work has shown that metastructures are effective at mitigating vibrations, but do not consider the effects of mass. This work takes mass into consideration by comparing a structure with vibration absorbers to a structure of equal mass with no absorbers. These structures are modeled as one-dimensional lumped mass models, chosen for simplicity. Results compare both the steady-state and the transient responses. As a quantitative performance measure, the H2 norm, which is related to the area under the frequency response function, is calculated and compared for both the metastructure and the baseline structure. These results show that it is possible to obtain a favorable vibration response without adding additional mass to the structure. Additionally, the performance measure is utilized to optimize the geometry of the structure, determine the optimal ratio of mass in the absorber to mass of the host structure, and determine the frequencies of the absorbers. The dynamic response of this model is verified using a finite element analysis.

Modeling water mass formation in the Mertz Glacier Polynya and Adélie Depression, East Antarctica

NASA Astrophysics Data System (ADS)

Marsland, S. J.; Bindoff, N. L.; Williams, G. D.; Budd, W. F.

2004-11-01

High rates of sea ice growth and brine rejection in the Mertz Glacier Polynya drive the production of dense continental shelf waters in the Adélie Depression. We consider the rate of outflow of waters having sufficient density to sink into the neighboring abyssal ocean and form Adélie Land Bottom Water (ALBW). Along with Weddell and Ross Sea Bottom Waters, the ALBW is an important source of Antarctic Bottom Water. The relevant processes are modeled using a variant of the Max Planck Institute Ocean Model (MPIOM) under daily NCEP-NCAR reanalysis forcing for the period 1991-2000. The orthogonal curvilinear horizontal grid allows for the construction of a global domain with high resolution in our region of interest. The modeled Mertz Glacier Polynya is realistic in location and extent, exhibiting low ice thickness (<0.4 m) and low ice fraction (<50%). The net surface ocean to atmosphere heat flux exceeds 200 W m2 and is dominated by sensible heat exchange. In wintertime (May through September inclusive), 7.5 m of sea ice forms over the Adélie Depression at a rate of 4.9 cm d-1: this results in annual average volumetric production of 99 km3 of sea ice. The associated brine release drives dense shelf water formation. The off-shelf flow of dense water exhibits strong interannual variability in response to variability in both atmospheric forcing and ocean preconditioning. Averaged over the period 1991-2000 the off shelf flow of dense water is 0.15 Sv: for a period of strong outflow (1993-1997), this increases to 0.24 Sv. Most of the outflow occurs during July through October, at a rate of 0.40 (0.63) Sv over the period 1991-2000 (1993-1997). The peak mean monthly outflow can exceed 1 Sv.

Innovative research of AD HOC network mobility model

NASA Astrophysics Data System (ADS)

Chen, Xin

2017-08-01

It is difficult for researchers of AD HOC network to conduct actual deployment during experimental stage as the network topology is changeable and location of nodes is unfixed. Thus simulation still remains the main research method of the network. Mobility model is an important component of AD HOC network simulation. It is used to describe the movement pattern of nodes in AD HOC network (including location and velocity, etc.) and decides the movement trail of nodes, playing as the abstraction of the movement modes of nodes. Therefore, mobility model which simulates node movement is an important foundation for simulation research. In AD HOC network research, mobility model shall reflect the movement law of nodes as truly as possible. In this paper, node generally refers to the wireless equipment people carry. The main research contents include how nodes avoid obstacles during movement process and the impacts of obstacles on the mutual relation among nodes, based on which a Node Self Avoiding Obstacle, i.e. NASO model is established in AD HOC network.

Transition from AdS universe to DS universe in the BPP model

NASA Astrophysics Data System (ADS)

Kim, Wontae; Yoon, Myungseok

2007-04-01

It can be shown that in the BPP model the smooth phase transition from the asymptotically decelerated AdS universe to the asymptotically accelerated DS universe is possible by solving the modified semiclassical equations of motion. This transition comes from noncommutative Poisson algebra, which gives the constant curvature scalars asymptotically. The decelerated expansion of the early universe is due to the negative energy density with the negative pressure induced by quantum back reaction, and the accelerated late-time universe comes from the positive energy and the negative pressure which behave like dark energy source in recent cosmological models.

Transformations of asymptotically AdS hyperbolic initial data and associated geometric inequalities

NASA Astrophysics Data System (ADS)

Cha, Ye Sle; Khuri, Marcus

2018-01-01

We construct transformations which take asymptotically AdS hyperbolic initial data into asymptotically flat initial data, and which preserve relevant physical quantities. This is used to derive geometric inequalities in the asymptotically AdS hyperbolic setting from counterparts in the asymptotically flat realm, whenever a geometrically motivated system of elliptic equations admits a solution. The inequalities treated here relate mass, angular momentum, charge, and horizon area. Furthermore, new mass-angular momentum inequalities in this setting are conjectured and discussed.

AdS 2 holographic dictionary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cvetic, Mirjam; Papadimitriou, Ioannis

Here, we construct the holographic dictionary for both running and constant dilaton solutions of the two dimensional Einstein-Maxwell-Dilaton theory that is obtained by a circle reduction from Einstein-Hilbert gravity with negative cosmological constant in three dimensions. This specific model ensures that the dual theory has a well defined ultraviolet completion in terms of a two dimensional conformal field theory, but our results apply qualitatively to a wider class of two dimensional dilaton gravity theories. For each type of solutions we perform holographic renormalization, compute the exact renormalized one-point functions in the presence of arbitrary sources, and derive the asymptotic symmetriesmore » and the corresponding conserved charges. In both cases we find that the scalar operator dual to the dilaton plays a crucial role in the description of the dynamics. Its source gives rise to a matter conformal anomaly for the running dilaton solutions, while its expectation value is the only non trivial observable for constant dilaton solutions. The role of this operator has been largely overlooked in the literature. We further show that the only non trivial conserved charges for running dilaton solutions are the mass and the electric charge, while for constant dilaton solutions only the electric charge is non zero. However, by uplifting the solutions to three dimensions we show that constant dilaton solutions can support non trivial extended symmetry algebras, including the one found by Compère, Song and Strominger, in agreement with the results of Castro and Song. Finally, we demonstrate that any solution of this specific dilaton gravity model can be uplifted to a family of asymptotically AdS 2 × S 2 or conformally AdS 2 × S 2 solutions of the STU model in four dimensions, including non extremal black holes. As a result, the four dimensional solutions obtained by uplifting the running dilaton solutions coincide with the so called ‘subtracted geometries�

AdS 2 holographic dictionary

DOE PAGES

Cvetic, Mirjam; Papadimitriou, Ioannis

2016-12-02

Here, we construct the holographic dictionary for both running and constant dilaton solutions of the two dimensional Einstein-Maxwell-Dilaton theory that is obtained by a circle reduction from Einstein-Hilbert gravity with negative cosmological constant in three dimensions. This specific model ensures that the dual theory has a well defined ultraviolet completion in terms of a two dimensional conformal field theory, but our results apply qualitatively to a wider class of two dimensional dilaton gravity theories. For each type of solutions we perform holographic renormalization, compute the exact renormalized one-point functions in the presence of arbitrary sources, and derive the asymptotic symmetriesmore » and the corresponding conserved charges. In both cases we find that the scalar operator dual to the dilaton plays a crucial role in the description of the dynamics. Its source gives rise to a matter conformal anomaly for the running dilaton solutions, while its expectation value is the only non trivial observable for constant dilaton solutions. The role of this operator has been largely overlooked in the literature. We further show that the only non trivial conserved charges for running dilaton solutions are the mass and the electric charge, while for constant dilaton solutions only the electric charge is non zero. However, by uplifting the solutions to three dimensions we show that constant dilaton solutions can support non trivial extended symmetry algebras, including the one found by Compère, Song and Strominger, in agreement with the results of Castro and Song. Finally, we demonstrate that any solution of this specific dilaton gravity model can be uplifted to a family of asymptotically AdS 2 × S 2 or conformally AdS 2 × S 2 solutions of the STU model in four dimensions, including non extremal black holes. As a result, the four dimensional solutions obtained by uplifting the running dilaton solutions coincide with the so called ‘subtracted geometries�

Selecting Value-Added Models for Postsecondary Institutional Assessment

ERIC Educational Resources Information Center

Steedle, Jeffrey T.

2012-01-01

Value-added scores from tests of college learning indicate how score gains compare to those expected from students of similar entering academic ability. Unfortunately, the choice of value-added model can impact results, and this makes it difficult to determine which results to trust. The research presented here demonstrates how value-added models…

Closed Timelike Curves in (2+1)-AdS Gravity

NASA Astrophysics Data System (ADS)

Valtancoli, P.

We build the (2+1)-AdS gravity generalization of the Gott time machine using a first-order formalism for solving the scattering of point sources. The two-body dynamics is solved by two invariant masses, whose difference is simply related to the total angular momentum of the system. We show how to build a time machine when at least one of the two invariant masses is no more real but acquires an imaginary part.

Feasibility Study of a Wearable Exoskeleton for Children: Is the Gait Altered by Adding Masses on Lower Limbs?

PubMed Central

Rossi, Stefano; Colazza, Alessandra; Petrarca, Maurizio; Castelli, Enrico; Cappa, Paolo; Krebs, Hermano Igo

2013-01-01

We are designing a pediatric exoskeletal ankle robot (pediatric Anklebot) to promote gait habilitation in children with Cerebral Palsy (CP). Few studies have evaluated how much or whether the unilateral loading of a wearable exoskeleton may have the unwanted effect of altering significantly the gait. The purpose of this study was to evaluate whether adding masses up to 2.5 kg, the estimated overall added mass of the mentioned device, at the knee level alters the gait kinematics. Ten healthy children and eight children with CP, with light or mild gait impairment, walked wearing a knee brace with several masses. Gait parameters and lower-limb joint kinematics were analyzed with an optoelectronic system under six conditions: without brace (natural gait) and with masses placed at the knee level (0.5, 1.0, 1.5, 2.0, 2.5 kg). T-tests and repeated measures ANOVA tests were conducted in order to find noteworthy differences among the trial conditions and between loaded and unloaded legs. No statistically significant differences in gait parameters for both healthy children and children with CP were observed in the five “with added mass” conditions. We found significant differences among “natural gait” and “with added masses” conditions in knee flexion and hip extension angles for healthy children and in knee flexion angle for children with CP. This result can be interpreted as an effect of the mechanical constraint induced by the knee brace rather than the effect associated with load increase. The study demonstrates that the mechanical constraint induced by the brace has a measurable effect on the gait of healthy children and children with CP and that the added mass up to 2.5 kg does not alter the lower limb kinematics. This suggests that wearable devices weighing 25 N or less will not noticeably modify the gait patterns of the population examined here. PMID:24023822

AdS-phobia, the WGC, the Standard Model and Supersymmetry

NASA Astrophysics Data System (ADS)

Gonzalo, Eduardo; Herráez, Alvaro; Ibáñez, Luis E.

2018-06-01

It has been recently argued that an embedding of the SM into a consistent theory of quantum gravity may imply important constraints on the mass of the lightest neutrino and the cosmological constant Λ4. The constraints come from imposing the absence of any non-SUSY AdS stable vacua obtained from any consistent compactification of the SM to 3 or 2 dimensions. This condition comes as a corollary of a recent extension of the Weak Gravity Conjecture (WGC) by Ooguri and Vafa. In this paper we study T 2 /Z N compactifications of the SM to two dimensions in which SM Wilson lines are projected out, leading to a considerable simplification. We analyze in detail a T 2 /Z 4 compactification of the SM in which both complex structure and Wilson line scalars are fixed and the potential is only a function of the area of the torus a 2. We find that the SM is not robust against the appearance of AdS vacua in 2D and hence would be by itself inconsistent with quantum gravity. On the contrary, if the SM is embedded at some scale M SS into a SUSY version like the MSSM, the AdS vacua present in the non-SUSY case disappear or become unstable. This means that WGC arguments favor a SUSY version of the SM, independently of the usual hierarchy problem arguments. In a T 2 /Z 4 compactification in which the orbifold action is embedded into the B - L symmetry the bounds on neutrino masses and the cosmological constant are recovered. This suggests that the MSSM should be extended with a U(1) B- L gauge group. In other families of vacua the spectrum of SUSY particles is further constrained in order to avoid the appearance of new AdS vacua or instabilities. We discuss a possible understanding of the little hierarchy problem in this context.

Spinning AdS loop diagrams: two point functions

NASA Astrophysics Data System (ADS)

Giombi, Simone; Sleight, Charlotte; Taronna, Massimo

2018-06-01

We develop a systematic approach to evaluating AdS loop amplitudes with spinning legs based on the spectral (or "split") representation of bulk-to-bulk propagators, which re-expresses loop diagrams in terms of spectral integrals and higher-point tree diagrams. In this work we focus on 2pt one-loop Witten diagrams involving totally symmetric fields of arbitrary mass and integer spin. As an application of this framework, we study the contribution to the anomalous dimension of higher-spin currents generated by bubble diagrams in higher-spin gauge theories on AdS.

Fermionic currents in AdS spacetime with compact dimensions

NASA Astrophysics Data System (ADS)

Bellucci, S.; Saharian, A. A.; Vardanyan, V.

2017-09-01

We derive a closed expression for the vacuum expectation value (VEV) of the fermionic current density in a (D +1 )-dimensional locally AdS spacetime with an arbitrary number of toroidally compactified Poincaré spatial dimensions and in the presence of a constant gauge field. The latter can be formally interpreted in terms of a magnetic flux treading the compact dimensions. In the compact subspace, the field operator obeys quasiperiodicity conditions with arbitrary phases. The VEV of the charge density is zero and the current density has nonzero components along the compact dimensions only. They are periodic functions of the magnetic flux with the period equal to the flux quantum and tend to zero on the AdS boundary. Near the horizon, the effect of the background gravitational field is small and the leading term in the corresponding asymptotic expansion coincides with the VEV for a massless field in the locally Minkowski bulk. Unlike the Minkowskian case, in the system consisting of an equal number of fermionic and scalar degrees of freedom, with same masses, charges and phases in the periodicity conditions, the total current density does not vanish. In these systems, the leading divergences in the scalar and fermionic contributions on the horizon are canceled and, as a consequence of that, the charge flux, integrated over the coordinate perpendicular to the AdS boundary, becomes finite. We show that in odd spacetime dimensions the fermionic fields realizing two inequivalent representations of the Clifford algebra and having equal phases in the periodicity conditions give the same contribution to the VEV of the current density. Combining the contributions from these fields, the current density in odd-dimensional C -,P - and T -symmetric models are obtained. As an application, we consider the ground state current density in curved carbon nanotubes described in terms of a (2 +1 )-dimensional effective Dirac model.

Heavy-light mesons in chiral AdS/QCD

NASA Astrophysics Data System (ADS)

Liu, Yizhuang; Zahed, Ismail

2017-06-01

We discuss a minimal holographic model for the description of heavy-light and light mesons with chiral symmetry, defined in a slab of AdS space. The model consists of a pair of chiral Yang-Mills and tachyon fields with specific boundary conditions that break spontaneously chiral symmetry in the infrared. The heavy-light spectrum and decay constants are evaluated explicitly. In the heavy mass limit the model exhibits both heavy-quark and chiral symmetry and allows for the explicit derivation of the one-pion axial couplings to the heavy-light mesons.

Warped AdS3 black holes

NASA Astrophysics Data System (ADS)

Song, Wei; Anninos, Dionysios; Li, Wei; Padi, Megha; Strominger, Andrew

2009-03-01

Three dimensional topologically massive gravity (TMG) with a negative cosmological constant -ell-2 and positive Newton constant G admits an AdS3 vacuum solution for any value of the graviton mass μ. These are all known to be perturbatively unstable except at the recently explored chiral point μell = 1. However we show herein that for every value of μell ≠ 3 there are two other (potentially stable) vacuum solutions given by SL(2,Bbb R) × U(1)-invariant warped AdS3 geometries, with a timelike or spacelike U(1) isometry. Critical behavior occurs at μell = 3, where the warping transitions from a stretching to a squashing, and there are a pair of warped solutions with a null U(1) isometry. For μell > 3, there are known warped black hole solutions which are asymptotic to warped AdS3. We show that these black holes are discrete quotients of warped AdS3 just as BTZ black holes are discrete quotients of ordinary AdS3. Moreover new solutions of this type, relevant to any theory with warped AdS3 solutions, are exhibited. Finally we note that the black hole thermodynamics is consistent with the hypothesis that, for μell > 3, the warped AdS3 ground state of TMG is holographically dual to a 2D boundary CFT with central charges c_R-formula and c_L-formula.

Warped AdS3 black holes

NASA Astrophysics Data System (ADS)

Anninos, Dionysios; Li, Wei; Padi, Megha; Song, Wei; Strominger, Andrew

2009-03-01

Three dimensional topologically massive gravity (TMG) with a negative cosmological constant -l-2 and positive Newton constant G admits an AdS3 vacuum solution for any value of the graviton mass μ. These are all known to be perturbatively unstable except at the recently explored chiral point μl = 1. However we show herein that for every value of μl ≠ 3 there are two other (potentially stable) vacuum solutions given by SL(2,Bbb R) × U(1)-invariant warped AdS3 geometries, with a timelike or spacelike U(1) isometry. Critical behavior occurs at μl = 3, where the warping transitions from a stretching to a squashing, and there are a pair of warped solutions with a null U(1) isometry. For μl > 3, there are known warped black hole solutions which are asymptotic to warped AdS3. We show that these black holes are discrete quotients of warped AdS3 just as BTZ black holes are discrete quotients of ordinary AdS3. Moreover new solutions of this type, relevant to any theory with warped AdS3 solutions, are exhibited. Finally we note that the black hole thermodynamics is consistent with the hypothesis that, for μl > 3, the warped AdS3 ground state of TMG is holographically dual to a 2D boundary CFT with central charges c_R-formula and c_L-formula.

Using School Lotteries to Evaluate the Value-Added Model

ERIC Educational Resources Information Center

Deutsch, Jonah

2013-01-01

There has been an active debate in the literature over the validity of value-added models. In this study, the author tests the central assumption of value-added models that school assignment is random relative to expected test scores conditional on prior test scores, demographic variables, and other controls. He uses a Chicago charter school's…

Teacher Effects, Value-Added Models, and Accountability

ERIC Educational Resources Information Center

Konstantopoulos, Spyros

2014-01-01

Background: In the last decade, the effects of teachers on student performance (typically manifested as state-wide standardized tests) have been re-examined using statistical models that are known as value-added models. These statistical models aim to compute the unique contribution of the teachers in promoting student achievement gains from grade…

Value-Added Models for the Pittsburgh Public Schools

ERIC Educational Resources Information Center

Johnson, Matthew; Lipscomb, Stephen; Gill, Brian; Booker, Kevin; Bruch, Julie

2012-01-01

At the request of Pittsburgh Public Schools (PPS) and the Pittsburgh Federation of Teachers (PFT), Mathematica has developed value-added models (VAMs) that aim to estimate the contributions of individual teachers, teams of teachers, and schools to the achievement growth of their students. The authors' work in estimating value-added in Pittsburgh…

Hairy black holes and the endpoint of AdS4 charged superradiance

NASA Astrophysics Data System (ADS)

Dias, Óscar J. C.; Masachs, Ramon

2017-02-01

We construct hairy black hole solutions that merge with the anti-de Sitter (AdS4) Reissner-Nordström black hole at the onset of superradiance. These hairy black holes have, for a given mass and charge, higher entropy than the corresponding AdS4-Reissner-Nordström black hole. Therefore, they are natural candidates for the endpoint of the charged superradiant instability. On the other hand, hairy black holes never dominate the canonical and grand-canonical ensembles. The zero-horizon radius of the hairy black holes is a soliton (i.e. a boson star under a gauge transformation). We construct our solutions perturbatively, for small mass and charge, so that the properties of hairy black holes can be used to testify and compare with the endpoint of initial value simulations. We further discuss the near-horizon scalar condensation instability which is also present in global AdS4-Reissner-Nordström black holes. We highlight the different nature of the near-horizon and superradiant instabilities and that hairy black holes ultimately exist because of the non-linear instability of AdS.

A model for heat and mass input control in GMAW

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smartt, H.B.; Einerson, C.J.

1993-05-01

This work describes derivation of a control model for electrode melting and heat and mass transfer from the electrode to the work piece in gas metal arc welding (GMAW). Specifically, a model is developed which allows electrode speed and welding speed to be calculated for given values of voltage and torch-to-base metal distance, as a function of the desired heat and mass input to the weldment. Heat input is given on a per unit weld length basis, and mass input is given in terms of transverse cross-sectional area added to the weld bead (termed reinforcement). The relationship to prior workmore » is discussed. The model was demonstrated using a computer-controlled welding machine and a proportional-integral (PI) controller receiving input from a digital filter. The difference between model-calculated welding current and measured current is used as controller feedback. The model is calibrated for use with carbon steel welding wire and base plate with Ar-CO[sub 2] shielding gas. Although the system is intended for application during spray transfer of molten metal from the electrode to the weld pool, satisfactory performance is also achieved during globular and streaming transfer. Data are presented showing steady-state and transient performance, as well as resistance to external disturbances.« less

Three dimensional view of the SYK/AdS duality

DOE Office of Scientific and Technical Information (OSTI.GOV)

Das, Sumit R.; Jevicki, Antal; Suzuki, Kenta

2017-09-05

We show that the spectrum of the SYK model can be interpreted as that of a 3D scalar coupled to gravity. The scalar has a mass which is at the Breitenholer-Freedman bound of AdS 2, and subject to a delta function potential at the center of the interval along the third direction. This, through Kaluza-Klein procedure on AdS 2 × (S 1)/Z 2, generates the spectrum reproducing the bi-local propagator at strong coupling. Furthermore, the leading 1/J correction calculated in this picture reproduces the known correction to the poles of the SYK propagator, providing credence to a conjecture that themore » bulk dual of this model can be interpreted as a three dimensional theory.« less

Using bioprocess stoichiometry to build a plant-wide mass balance based steady-state WWTP model.

PubMed

Ekama, G A

2009-05-01

Steady-state models are useful for design of wastewater treatment plants (WWTPs) because they allow reactor sizes and interconnecting flows to be simply determined from explicit equations in terms of unit operation performance criteria. Once the overall WWTP scheme is established and the main system defining parameters of the individual unit operations estimated, dynamic models can be applied to the connected unit operations to refine their design and evaluate their performance under dynamic flow and load conditions. To model anaerobic digestion (AD) within plant-wide WWTP models, not only COD and nitrogen (N) but also carbon (C) fluxes entering the AD need to be defined. Current plant-wide models, like benchmark simulation model No 2 (BSM2), impose a C flux at the AD influent. In this paper, the COD and N mass balance steady-state models of activated sludge (AS) organics degradation, nitrification and denitrification (ND) and anaerobic (AD) and aerobic (AerD) digestion of wastewater sludge are extended and linked with bioprocess transformation stoichiometry to form C, H, O, N, chemical oxygen demand (COD) and charge mass balance based models so that also C (and H and O) can be tracked through the whole WWTP. By assigning a stoichiometric composition (x, y, z and a in C(x)H(y)O(z)N(a)) to each of the five main influent wastewater organic fractions and ammonia, these, and the products generated from them via the biological processes, are tracked through the WWTP. The model is applied to two theoretical case study WWTPs treating the same raw wastewater (WW) to the same final sludge residual biodegradable COD. It is demonstrated that much useful information can be generated with the relatively simple steady-state models to aid WWTP layout design and track the different products exiting the WWTP via the solid, liquid and gas streams, such as aerobic versus anaerobic digestion of waste activated sludge, N loads in recycle streams, methane production for energy recovery

The Potential Consequence of Using Value-Added Models to Evaluate Teachers

ERIC Educational Resources Information Center

Shen, Zuchao; Simon, Carlee Escue; Kelcey, Ben

2016-01-01

Value-added models try to separate the contribution of individual teachers or schools to students' learning growth measured by standardized test scores. There is a policy trend to use value-added modeling to evaluate teachers because of its face validity and superficial objectiveness. This article investigates the potential long term consequences…

Mass modeling for bars

NASA Technical Reports Server (NTRS)

Butler, Thomas G.

1987-01-01

Methods of modeling mass for bars are surveyed. A method for extending John Archer's concept of consistent mass beyond just translational inertia effects is included. Recommendations are given for various types of modeling situations.

Throat quantization of the Schwarzschild-Tangherlini(-AdS) black hole

NASA Astrophysics Data System (ADS)

Maeda, Hideki

2018-01-01

By the throat quantization pioneered by Louko and Mäkelä, we derive the mass and area/entropy spectra for the Schwarzschild-Tangherlini-type asymptotically flat or AdS vacuum black hole in arbitrary dimensions. Using the WKB approximation for black holes with large mass, we show that area/entropy is equally spaced for asymptotically flat black holes, while mass is equally spaced for asymptotically AdS black holes. Exact spectra can be obtained for toroidal AdS black holes in arbitrary dimensions including the three-dimensional BTZ black hole.

What's the Value of VAM (Value-Added Modeling)?

ERIC Educational Resources Information Center

Scherrer, Jimmy

2012-01-01

The use of value-added modeling (VAM) in school accountability is expanding, but deciding how to embrace VAM is difficult. Various experts say it's too unreliable, causes more harm than good, and has a big margin for error. Others assert VAM is imperfect but useful, and provides valuable feedback. A closer look at the models, and their use,…

Mass attenuation coefficient of tannin-added Rhizophora spp. particleboards at 16.59-25.56 keV photons, and 137Cs and 60Co gamma energies.

PubMed

Yusof, Mohd Fahmi Mohd; Hamid, Puteri Nor Khatijah Abd; Tajuddin, Abd Aziz; Hashim, Rokiah; Bauk, Sabar; Isa, Norriza Mohd; Isa, Muhammad Jamal Md

2017-09-01

The aim of this study was to determine the suitability of tannin-added Rhizophora spp. particleboards as phantom materials in the application of low- and high-energy photons. The tannin-added Rhizophora spp. particleboards and density plug phantoms were created with a target density of 1.0 g/cm 3 . The elemental composition and effective atomic number of the particleboards were measured using energy dispersive X-ray analysis. The mass attenuation coefficient of the particleboards for low-energy photons were measured using the attenuation of X-ray fluorescence. The mass attenuation coefficients of high-energy photons were measured using the attenuation of 137 Cs and 60 Co gamma energies. The results were compared to the calculated value of water using XCOM calculations. The results showed that the effective atomic number and mass attenuation coefficients of tannin-added Rhizophora spp. particleboards were similar to those of water, indicating the suitability of tannin-added Rhizophora spp. particleboards as phantom materials for low- and high-energy photons.

Value-Added Models: What the Experts Say

ERIC Educational Resources Information Center

Amrein-Beardsley, Audrey; Pivovarova, Margarita; Geiger, Tray J.

2016-01-01

Being an expert involves explaining how things are supposed to work, and, perhaps more important, why things might not work as supposed. In this study, researchers surveyed scholars with expertise in value-added models (VAMs) to solicit their opinions about the uses and potential of VAMs for teacher-level accountability purposes (for example, in…

Trust recovery model of Ad Hoc network based on identity authentication scheme

NASA Astrophysics Data System (ADS)

Liu, Jie; Huan, Shuiyuan

2017-05-01

Mobile Ad Hoc network trust model is widely used to solve mobile Ad Hoc network security issues. Aiming at the problem of reducing the network availability caused by the processing of malicious nodes and selfish nodes in mobile Ad Hoc network routing based on trust model, an authentication mechanism based on identity authentication mobile Ad Hoc network is proposed, which uses identity authentication to identify malicious nodes, And trust the recovery of selfish nodes in order to achieve the purpose of reducing network congestion and improving network quality. The simulation results show that the implementation of the mechanism can effectively improve the network availability and security.

The hybrid mass-spring pendulum model of human leg swinging: stiffness in the control of cycle period.

PubMed

Obusek, J P; Holt, K G; Rosenstein, R M

1995-07-01

Human leg swinging is modeled as the harmonic motion of a hybrid mass-spring pendulum. The cycle period is determined by a gravitational component and an elastic component, which is provided by the attachment of a soft-tissue/muscular spring of variable stiffness. To confirm that the stiffness of the spring changes with alterations in the inertial properties of the oscillator and that stiffness is relevant for the control of cycle period, we conducted this study in which the simple pendulum equivalent length was experimentally manipulated by adding mass to the ankle of a comfortably swinging leg. Twenty-four young, healthy adults were videotaped as they swung their right leg under four conditions: no added mass and with masses of 2.27, 4.55, and 6.82kg added to the ankle. Strong, linear relationships between the acceleration and displacement of the swinging leg within subjects and conditions were found, confirming the motion's harmonic nature. Cycle period significantly increased with the added mass. However, the observed increases were not as large as would be predicted by the induced changes in the gravitational component alone. These differences were interpreted as being due to increases in the active muscular stiffness. Significant linear increases in the elastic component (and hence stiffness) were demonstrated with increases in the simple pendulum equivalent length in 20 of the individual subjects, with r2 values ranging between 0.89 and 0.99. Significant linear relationships were also demonstrated between the elastic and gravitational components in 22 subjects, with individual r2 values between 0.90 and 0.99.(ABSTRACT TRUNCATED AT 250 WORDS)

Exact microstate counting for dyonic black holes in AdS4

NASA Astrophysics Data System (ADS)

Benini, Francesco; Hristov, Kiril; Zaffaroni, Alberto

2017-08-01

We present a counting of microstates of a class of dyonic BPS black holes in AdS4 which precisely reproduces their Bekenstein-Hawking entropy. The counting is performed in the dual boundary description, that provides a non-perturbative definition of quantum gravity, in terms of a twisted and mass-deformed ABJM theory. We evaluate its twisted index and propose an extremization principle to extract the entropy, which reproduces the attractor mechanism in gauged supergravity.

Comparison between overweight due to pregnancy and due to added weight to simulate body mass distribution in pregnancy.

PubMed

Aguiar, Liliana; Santos-Rocha, Rita; Vieira, Filomena; Branco, Marco; Andrade, Carlos; Veloso, António

2015-10-01

The assessment of biomechanical loading in the musculoskeletal system of the pregnant women is particularly interesting since they are subject to morphological, physiological and hormonal changes, which may lead to adaptations in gait. The purpose of this study was to analyze the effect of the increased mass in the trunk associated to pregnancy on the lower limb and pelvis, during walking, on temporal-distance parameters, joint range of motion and moments of force, by comparing a pregnant women group to a non-pregnant group, and to this group while carrying a 5 kg additional load located in the abdomen and breasts during walking, to understand which gait adaptations may be more related with the increased trunk mass, or if may be more associated with other factors such as the girth of the thigh. The subjects performed a previous 12 min training adaption to the added load. To calculate ankle, knee and hip joint angles and moments of force, a three-dimensional biomechanical model was developed. The inverse dynamics method was used to estimate net joint moments of force. The increased mass of the anterior trunk associated with second trimester of pregnancy may influence some gait variables such as the left step time, left and right stance times, double limb support time, maximum hip extension, maximum pelvic right obliquity, pelvic obliquity range of motion, maximum transversal left rotation and peak hip flexion moments of force. Copyright © 2015 Elsevier B.V. All rights reserved.

Autoimmune Manifestations in the 3xTg-AD Model of Alzheimer's Disease

PubMed Central

Marchese, Monica; Cowan, David; Head, Elizabeth; Ma, Donglai; Karimi, Khalil; Ashthorpe, Vanessa; Kapadia, Minesh; Zhao, Hui; Davis, Paulina; Sakic, Boris

2015-01-01

Background Immune system activation is frequently reported in patients with Alzheimer's disease (AD). However, it remains unknown whether this is a cause, a consequence, or an epiphenomenon of brain degeneration. Objective The present study examines whether immunological abnormalities occur in a well-established murine AD model and if so, how they relate temporally to behavioral deficits and neuropathology. Methods A broad battery of tests was employed to assess behavioral performance and autoimmune/inflammatory markers in 3xTg-AD (AD) mice and wild type controls from 1.5 to 12 months of age. Results Aged AD mice displayed severe manifestations of systemic autoimmune/inflammatory disease, as evidenced by splenomegaly, hepatomegaly, elevated serum levels of anti-nuclear/anti-dsDNA antibodies, low hematocrit, and increased number of double-negative T splenocytes. However, anxiety-related behavior and altered spleen function were evident as early as 2 months of age, thus preceding typical AD-like brain pathology. Moreover, AD mice showed altered olfaction and impaired “cognitive” flexibility in the first 6 months of life, suggesting mild cognitive impairment-like manifestations before general learning/memory impairments emerged at an older age. Interestingly, all of these features were present in 3xTg-AD mice prior to significant amyloid-β or tau pathology. Conclusion The results indicate that behavioral deficits in AD mice develop in parallel with systemic autoimmune/inflammatory disease. These changes antedate AD-like neuropathology, thus supporting a causal link between autoimmunity and aberrant behavior. Consequently, 3xTg-AD mice may be a useful model in elucidating the role of immune system in the etiology of AD. PMID:24150111

A family of triaxial modified Hubble mass models: Effects of the additional radial functions

NASA Astrophysics Data System (ADS)

Das, Mousumi; Thakur, Parijat; Ann, H. B.

2005-03-01

The projected properties of triaxial generalization of the modified Hubble mass models are studied. These models are constructed by adding the additional radial functions, each multiplied by a low-order spherical harmonic, to the models of [Chakraborty, D.K., Thakur, P., 2000. MNRAS 318, 1273]. The projected surface density of mass models can be calculated analytically which allows us to derive the analytic expressions of axial ratio and position angle of major axis of constant density elliptical contours at asymptotic radii. The models are more general than those studied earlier in the sense that the inclusions of additional terms in density distribution, allow one to produce varieties of the radial profile of axial ratio and position angle, in particular, their small scale variations at inner radii. Strong correlations are found to exist between the observed axial ratio evaluated at 0.25Re and at 4Re which occupy well-separated regions in the parameter space for different choices of the intrinsic axial ratios. These correlations can be exploited to predict the intrinsic shape of the mass model, independent of the viewing angles. Using Bayesian statistics, the result of a test case launched for an estimation of the shape of a model galaxy is found to be satisfactory.

Influence of pectins on the solubility and the molar mass distribution of dehydrogenative polymers (DHPs, lignin model compounds).

PubMed

Cathala, B; Monties, B

2001-07-19

Dehydrogenation polymers (DHPs, lignin model compounds) were synthesized in the presence of increasing pectin concentrations using two different methods. The first method ('Zutropfverfahren', ZT) consists in the slow adding of monomers whereas in the second method ('Zulaufverfahren', ZL) all the reactants are added simultaneously. DHPs solubility increases with the pectin concentration in the ZT experiments and remains stable in the ZL experiments. Covalent bonds between pectin and DHP are formed during ZT polymerization resulting in lignin carbohydrate complex (LCC) which keeps the unbound DHPs in solution by the formation of aggregate or micelle-like structures. In contrast LCC are not formed during the ZL process which behave like the DHP reference. The ZT DHP molar masses increase observed is attributed to the reactivity of the high molar mass polymer solubilized by the LCC whereas ZL higher molar mass polymers are precipitated out of the solution and cannot react further.

The Discrepancy between Einstein Mass and Dynamical Mass for SIS and Power-law Mass Models

NASA Astrophysics Data System (ADS)

Li, Rui; Wang, Jiancheng; Shu, Yiping; Xu, Zhaoyi

2018-03-01

We investigate the discrepancy between the two-dimensional projected lensing mass and the dynamical mass for an ensemble of 97 strong gravitational lensing systems discovered by the Sloan Lens ACS Survey, the BOSS Emission-Line Lens Survey (BELLS), and the BELLS for GALaxy-Lyα EmitteR sYstems Survey. We fit the lensing data to obtain the Einstein mass and use the velocity dispersion of the lensing galaxies provided by the Sloan Digital Sky Survey to get the projected dynamical mass within the Einstein radius by assuming the power-law mass approximation. The discrepancy is found to be obvious and quantified by Bayesian analysis. For the singular isothermal sphere mass model, we obtain that the Einstein mass is 20.7% more than the dynamical mass, and the discrepancy increases with the redshift of the lensing galaxies. For the more general power-law mass model, the discrepancy still exists within a 1σ credible region. We suspect the main reason for this discrepancy is mass contamination, including all invisible masses along the line of sight. In addition, the measurement errors and the approximation of the mass models could also contribute to the discrepancy.

Period adding cascades: experiment and modeling in air bubbling.

PubMed

Pereira, Felipe Augusto Cardoso; Colli, Eduardo; Sartorelli, José Carlos

2012-03-01

Period adding cascades have been observed experimentally/numerically in the dynamics of neurons and pancreatic cells, lasers, electric circuits, chemical reactions, oceanic internal waves, and also in air bubbling. We show that the period adding cascades appearing in bubbling from a nozzle submerged in a viscous liquid can be reproduced by a simple model, based on some hydrodynamical principles, dealing with the time evolution of two variables, bubble position and pressure of the air chamber, through a system of differential equations with a rule of detachment based on force balance. The model further reduces to an iterating one-dimensional map giving the pressures at the detachments, where time between bubbles come out as an observable of the dynamics. The model has not only good agreement with experimental data, but is also able to predict the influence of the main parameters involved, like the length of the hose connecting the air supplier with the needle, the needle radius and the needle length.

Using a laboratory-based growth model to estimate mass- and temperature-dependent growth parameters across populations of juvenile Chinook Salmon

USGS Publications Warehouse

Perry, Russell W.; Plumb, John M.; Huntington, Charles

2015-01-01

To estimate the parameters that govern mass- and temperature-dependent growth, we conducted a meta-analysis of existing growth data from juvenile Chinook Salmon Oncorhynchus tshawytscha that were fed an ad libitum ration of a pelleted diet. Although the growth of juvenile Chinook Salmon has been well studied, research has focused on a single population, a narrow range of fish sizes, or a narrow range of temperatures. Therefore, we incorporated the Ratkowsky model for temperature-dependent growth into an allometric growth model; this model was then fitted to growth data from 11 data sources representing nine populations of juvenile Chinook Salmon. The model fit the growth data well, explaining 98% of the variation in final mass. The estimated allometric mass exponent (b) was 0.338 (SE = 0.025), similar to estimates reported for other salmonids. This estimate of b will be particularly useful for estimating mass-standardized growth rates of juvenile Chinook Salmon. In addition, the lower thermal limit, optimal temperature, and upper thermal limit for growth were estimated to be 1.8°C (SE = 0.63°C), 19.0°C (SE = 0.27°C), and 24.9°C (SE = 0.02°C), respectively. By taking a meta-analytical approach, we were able to provide a growth model that is applicable across populations of juvenile Chinook Salmon receiving an ad libitum ration of a pelleted diet.

Evaluating Special Educator Effectiveness: Addressing Issues Inherent to Value-Added Modeling

ERIC Educational Resources Information Center

Steinbrecher, Trisha D.; Selig, James P.; Cosbey, Joanna; Thorstensen, Beata I.

2014-01-01

States are increasingly using value-added approaches to evaluate teacher effectiveness. There is much debate regarding whether these methods should be employed and, if employed, what role such methods should play in comprehensive teacher evaluation systems. In this article, we consider the use of value-added modeling (VAM) to evaluate special…

Financial and health literacy predict incident AD dementia and AD pathology

PubMed Central

Yu, Lei; Wilson, Robert S.; Schneider, Julie A.; Bennett, David A.; Boyle, Patricia A.

2017-01-01

Background Domain specific literacy is a multidimensional construct that requires multiple resources including cognitive and non-cognitive factors. Objective We test the hypothesis that domain specific literacy is associated with AD dementia and AD pathology after controlling for cognition. Methods Participants were community based older persons who completed a baseline literacy assessment, underwent annual clinical evaluations for up to 8 years and agreed to organ donation after death. Financial and health literacy was measured using 32 questions and cognition was measured using 19 tests. Annual diagnosis of AD dementia followed standard criteria. AD pathology was examined post-mortem by quantifying plaques and tangles. Cox models examined the association of literacy with incident AD dementia. Performance of model prediction for incident AD dementia was assessed using indices for integrated discrimination improvement and continuous net reclassification improvement. Linear regression models examined the independent association of literacy with AD pathology in autopsied participants. Results All 805 participants were free of dementia at baseline and 102 (12.7%) developed AD dementia during the follow-up. Lower literacy was associated with higher risk for incident AD dementia (p<0.001), and the association persisted after controlling for cognition (Hazard Ratio=1.50, p=0.004). The model including the literacy measure had better predictive performance than the one with demographics and cognition only. Lower literacy also was associated with higher burden of AD pathology after controlling for cognition (β=0.07, p=0.035). Conclusion Literacy predicts incident AD dementia and AD pathology in community-dwelling older persons, and the association is independent of traditional measures of cognition. PMID:28157101

Modeling of the UAE Wind Turbine for Refinement of FAST{_}AD

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jonkman, J. M.

The Unsteady Aerodynamics Experiment (UAE) research wind turbine was modeled both aerodynamically and structurally in the FAST{_}AD wind turbine design code, and its response to wind inflows was simulated for a sample of test cases. A study was conducted to determine why wind turbine load magnitude discrepancies-inconsistencies in aerodynamic force coefficients, rotor shaft torque, and out-of-plane bending moments at the blade root across a range of operating conditions-exist between load predictions made by FAST{_}AD and other modeling tools and measured loads taken from the actual UAE wind turbine during the NASA-Ames wind tunnel tests. The acquired experimental test data representmore » the finest, most accurate set of wind turbine aerodynamic and induced flow field data available today. A sample of the FAST{_}AD model input parameters most critical to the aerodynamics computations was also systematically perturbed to determine their effect on load and performance predictions. Attention was focused on the simpler upwind rotor configuration, zero yaw error test cases. Inconsistencies in input file parameters, such as aerodynamic performance characteristics, explain a noteworthy fraction of the load prediction discrepancies of the various modeling tools.« less

Value-Added Models and the Measurement of Teacher Productivity. CALDER Working Paper No. 54

ERIC Educational Resources Information Center

Harris, Douglas; Sass, Tim; Semykina, Anastasia

2010-01-01

Research on teacher productivity, and recently developed accountability systems for teachers, rely on value-added models to estimate the impact of teachers on student performance. The authors test many of the central assumptions required to derive value-added models from an underlying structural cumulative achievement model and reject nearly all…

Higher Daily Energy Expenditure and Respiratory Quotient, Rather Than Fat-Free Mass, Independently Determine Greater ad Libitum Overeating.

PubMed

Piaggi, Paolo; Thearle, Marie S; Krakoff, Jonathan; Votruba, Susanne B

2015-08-01

Body fat-free mass (FFM), energy expenditure (EE), and respiratory quotient (RQ) are known predictors of daily food intake. Because FFM largely determines EE, it is unclear whether body composition per se or the underlying metabolism drives dietary intake. The objective of the study was to test whether 24-hour measures of EE and RQ and their components influence ad libitum food intake independently of FFM. One hundred seven healthy individuals (62 males/45 females, 84 Native Americans/23 whites; age 33 ± 8 y; body mass index 33 ± 8 kg/m(2); body fat 31% ± 8%) had 24-hour measures of EE in a whole-room indirect calorimeter during energy balance, followed by 3 days of ad libitum food intake using computerized vending machine systems. Body composition was estimated by dual-energy x-ray absorptiometry. FFM, 24-hour EE, RQ, spontaneous physical activity, sleeping EE (sleeping metabolic rate), awake and fed thermogenesis, and ad libitum food intake (INTAKE) were measured. Higher 24-hour RQ (P < .001, partial R(2) = 16%) and EE (P = .01, partial R(2) = 7%), but not FFM (P = .65), were independent predictors of INTAKE. Mediation analysis demonstrated that 24-hour EE is responsible for 80% of the FFM effect on INTAKE (44.5 ± 16.9 kcal ingested per kilogram of FFM, P= .01), whereas the unique effect due to solely FFM was negligible (10.6 ± 23.2, P = .65). Spontaneous physical activity (r = 0.33, P = .001), but not sleeping metabolic rate (P = .71), positively predicted INTAKE, whereas higher awake and fed thermogenesis determined greater INTAKE only in subjects with a body mass index of 29 kg/m(2) or less (r = 0.44, P = .01). EE and RQ, rather than FFM, independently determine INTAKE, suggesting that competitive energy-sensing mechanisms driven by the preferential macronutrient oxidation and total energy demands may regulate food intake.

Higher Daily Energy Expenditure and Respiratory Quotient, Rather Than Fat-Free Mass, Independently Determine Greater ad Libitum Overeating

PubMed Central

Thearle, Marie S.; Krakoff, Jonathan; Votruba, Susanne B.

2015-01-01

Context: Body fat-free mass (FFM), energy expenditure (EE), and respiratory quotient (RQ) are known predictors of daily food intake. Because FFM largely determines EE, it is unclear whether body composition per se or the underlying metabolism drives dietary intake. Objective: The objective of the study was to test whether 24-hour measures of EE and RQ and their components influence ad libitum food intake independently of FFM. Design and Participants: One hundred seven healthy individuals (62 males/45 females, 84 Native Americans/23 whites; age 33 ± 8 y; body mass index 33 ± 8 kg/m2; body fat 31% ± 8%) had 24-hour measures of EE in a whole-room indirect calorimeter during energy balance, followed by 3 days of ad libitum food intake using computerized vending machine systems. Body composition was estimated by dual-energy x-ray absorptiometry. Main Outcome Measures: FFM, 24-hour EE, RQ, spontaneous physical activity, sleeping EE (sleeping metabolic rate), awake and fed thermogenesis, and ad libitum food intake (INTAKE) were measured. Results: Higher 24-hour RQ (P < .001, partial R2 = 16%) and EE (P = .01, partial R2 = 7%), but not FFM (P = .65), were independent predictors of INTAKE. Mediation analysis demonstrated that 24-hour EE is responsible for 80% of the FFM effect on INTAKE (44.5 ± 16.9 kcal ingested per kilogram of FFM, P= .01), whereas the unique effect due to solely FFM was negligible (10.6 ± 23.2, P = .65). Spontaneous physical activity (r = 0.33, P = .001), but not sleeping metabolic rate (P = .71), positively predicted INTAKE, whereas higher awake and fed thermogenesis determined greater INTAKE only in subjects with a body mass index of 29 kg/m2 or less (r = 0.44, P = .01). Conclusions: EE and RQ, rather than FFM, independently determine INTAKE, suggesting that competitive energy-sensing mechanisms driven by the preferential macronutrient oxidation and total energy demands may regulate food intake. PMID:26086330

Lensed Type Ia supernovae as probes of cluster mass models

Science.gov Websites

SAO/NASA ADS Astronomy Abstract Service Title: Lensed Type Ia supernovae as probes of cluster mass Origin: OUP Astronomy Keywords: gravitational lensing: strong, supernovae: general, galaxies: clusters

Partition functions with spin in AdS2 via quasinormal mode methods

DOE PAGES

Keeler, Cynthia; Lisbão, Pedro; Ng, Gim Seng

2016-10-12

We extend the results of [1], computing one loop partition functions for massive fields with spin half in AdS 2 using the quasinormal mode method proposed by Denef, Hartnoll, and Sachdev [2]. We find the finite representations of SO(2,1) for spin zero and spin half, consisting of a highest weight state |hi and descendants with non-unitary values of h. These finite representations capture the poles and zeroes of the one loop determinants. Together with the asymptotic behavior of the partition functions (which can be easily computed using a large mass heat kernel expansion), these are sufficient to determine the fullmore » answer for the one loop determinants. We also discuss extensions to higher dimensional AdS 2n and higher spins.« less

Predictive models of radiative neutrino masses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Julio, J., E-mail: julio@lipi.go.id

2016-06-21

We discuss two models of radiative neutrino mass generation. The first model features one–loop Zee model with Z{sub 4} symmetry. The second model is the two–loop neutrino mass model with singly- and doubly-charged scalars. These two models fit neutrino oscillation data well and predict some interesting rates for lepton flavor violation processes.

Maintained total body water content and serum sodium concentrations despite body mass loss in female ultra-runners drinking ad libitum during a 100 km race.

PubMed

Knechtle, Beat; Senn, Oliver; Imoberdorf, Reinhard; Joleska, Irena; Wirth, Andrea; Knechtle, Patrizia; Rosemann, Thomas

2010-01-01

We investigated in 11 female ultra-runners during a 100 km ultra-run, the association between fluid intake and prevalence of exercise-associated hyponatremia in a cross-sectional study. Athletes drank ad libitum and recorded their fluid intake. They competed at 8.0 (1.0) km/h and finished within 762 (91) min. Fluid intake was 4.1 (1.3) L during the race, equal to 0.3 (0.1) L/h. Body mass decreased by 1.5 kg (p< 0.01); pre race body mass was related to speed in the race (r = -0.78, p< 0.05); and change (Delta) in body mass was not associated with speed in the race. Change in body mass was positively (r = 0.70; p< 0.05), and Delta urinary specific gravity negatively (r = -0.67; p< 0.05), correlated to Delta percent total body water. Changes in body mass were not related to fluid intake during the race. Fluid intake was not correlated to running speed and showed no association with either Delta percent total body water nor Delta [Na] in plasma. Fluid intake showed no relationship with both Delta haematocrit and Delta plasma volume. No exercise-associated hyponatremia occurred. Female ultra- runners consuming fluids ad libitum during the race experienced no fluid overload, and ad libitum drinking protects against exercise-associated hyponatremia. The reported higher incidence of exercise-associated hyponatremia in women is not really a gender effect but due to women being more prone to overdrink.

Properties of added variable plots in Cox's regression model.

PubMed

Lindkvist, M

2000-03-01

The added variable plot is useful for examining the effect of a covariate in regression models. The plot provides information regarding the inclusion of a covariate, and is useful in identifying influential observations on the parameter estimates. Hall et al. (1996) proposed a plot for Cox's proportional hazards model derived by regarding the Cox model as a generalized linear model. This paper proves and discusses properties of this plot. These properties make the plot a valuable tool in model evaluation. Quantities considered include parameter estimates, residuals, leverage, case influence measures and correspondence to previously proposed residuals and diagnostics.

The AdS3 propagator and the fate of locality

NASA Astrophysics Data System (ADS)

Chen, Hongbin; Fitzpatrick, A. Liam; Kaplan, Jared; Li, Daliang

2018-04-01

We recently used Virasoro symmetry considerations to propose an exact formula for a bulk proto-field ϕ in AdS3. In this paper we study the propagator < ϕϕ>. We show that many techniques from the study of conformal blocks can be generalized to compute it, including the semiclassical monodromy method and both forms of the Zamolodchikov recursion relations. When the results from recursion are expanded at large central charge, they match gravitational perturbation theory for a free scalar field coupled to gravity in our chosen gauge. We find that although the propagator is finite and well-defined at long distances, its perturbative expansion in {G}_N=3/2c exhibits UV/IR mixing effects. If we nevertheless interpret < ϕϕ> as a probe of bulk locality, then when {G}_{N{m}_{φ }}≪ 1 locality breaks down at the new short-distance scale {σ}_{\\ast}˜ √[4]{G_N{R}_{AdS}^3} . For ϕ with very large bulk mass, or at small central charge, bulk locality fails at the AdS length scale. In all cases, locality `breakdown' manifests as singularities or branch cuts at spacelike separation arising from non-perturbative quantum gravitational effects.

Ocular changes in TgF344-AD rat model of Alzheimer's disease.

PubMed

Tsai, Yuchun; Lu, Bin; Ljubimov, Alexander V; Girman, Sergey; Ross-Cisneros, Fred N; Sadun, Alfredo A; Svendsen, Clive N; Cohen, Robert M; Wang, Shaomei

2014-01-29

Alzheimer's disease (AD) is the most common neurodegenerative disorder characterized by progressive decline in learning, memory, and executive functions. In addition to cognitive and behavioral deficits, vision disturbances have been reported in early stage of AD, well before the diagnosis is clearly established. To further investigate ocular abnormalities, a novel AD transgenic rat model was analyzed. Transgenic (Tg) rats (TgF344-AD) heterozygous for human mutant APPswe/PS1ΔE9 and age-matched wild type (WT) rats, as well as 20 human postmortem retinal samples from both AD and healthy donors were used. Visual function in the rodent was analyzed using the optokinetic response and luminance threshold recording from the superior colliculus. Immunohistochemistry on retinal and brain sections was used to detect various markers including amyloid-β (Aβ) plaques. As expected, Aβ plaques were detected in the hippocampus, cortex, and retina of Tg rats. Plaque-like structures were also found in two AD human whole-mount retinas. The choroidal thickness was significantly reduced in both Tg rat and in AD human eyes when compared with age-matched controls. Tg rat eyes also showed hypertrophic retinal pigment epithelial cells, inflammatory cells, and upregulation of complement factor C3. Although visual acuity was lower in Tg than in WT rats, there was no significant difference in the retinal ganglion cell number and retinal vasculature. In this study, we observed pathological changes in the choroid and in RPE cells in the TgF344-AD rat model; choroidal thinning was observed further in human AD retina. Along with Ab deposition, the inflammatory response was manifested by microglial recruitment and complement activation. Further studies are needed to elucidate the significance and mechanisms of these pathological changes [corrected].

Stability of Teacher Value-Added Rankings across Measurement Model and Scaling Conditions

ERIC Educational Resources Information Center

Hawley, Leslie R.; Bovaird, James A.; Wu, ChaoRong

2017-01-01

Value-added assessment methods have been criticized by researchers and policy makers for a number of reasons. One issue includes the sensitivity of model results across different outcome measures. This study examined the utility of incorporating multivariate latent variable approaches within a traditional value-added framework. We evaluated the…

Digital Quantum Simulation of Minimal AdS /CFT

NASA Astrophysics Data System (ADS)

García-Álvarez, L.; Egusquiza, I. L.; Lamata, L.; del Campo, A.; Sonner, J.; Solano, E.

2017-07-01

We propose the digital quantum simulation of a minimal AdS /CFT model in controllable quantum platforms. We consider the Sachdev-Ye-Kitaev model describing interacting Majorana fermions with randomly distributed all-to-all couplings, encoding nonlocal fermionic operators onto qubits to efficiently implement their dynamics via digital techniques. Moreover, we also give a method for probing nonequilibrium dynamics and the scrambling of information. Finally, our approach serves as a protocol for reproducing a simplified low-dimensional model of quantum gravity in advanced quantum platforms as trapped ions and superconducting circuits.

Absolute dimensions of eclipsing binaries. XXVI.. Setting a new standard: Masses, radii, and abundances for the F-type systems AD Bootis VZ Hydrae, and WZ Ophiuchi

NASA Astrophysics Data System (ADS)

Clausen, J. V.; Torres, G.; Bruntt, H.; Andersen, J.; Nordström, B.; Stefanik, R. P.; Latham, D. W.; Southworth, J.

2008-09-01

Context: Accurate mass, radius, and abundance determinations from binaries provide important information on stellar evolution, fundamental to central fields in modern astrophysics and cosmology. Aims: We aim to determine absolute dimensions and abundances for the three F-type main-sequence detached eclipsing binaries AD Boo, VZ Hya, and WZ Oph and to perform a detailed comparison with results from recent stellar evolutionary models. Methods: uvby light curves and uvbyβ standard photometry were obtained with the Strömgren Automatic Telescope at ESO, La Silla, radial velocity observations at CfA facilities, and supplementary high-resolution spectra with ESO's FEROS spectrograph. State-of-the-art methods were applied for the analyses: the EBOP and Wilson-Devinney binary models, two-dimensional cross-correlation and disentangling, and the VWA abundance analysis tool. Results: Masses and radii that are precise to 0.5-0.7% and 0.4-0.9%, respectively, have been established for the components, which span the ranges of 1.1 to 1.4 M⊙ and 1.1 to 1.6 R⊙. The [Fe/H] abundances are from -0.27 to +0.10, with uncertainties between 0.07 and 0.15 dex. We find indications of a slight α-element overabundance of [α/Fe] ˜ + 0.1 for WZ Oph. The secondary component of AD Boo and both components of WZ Oph appear to be slightly active. Yale-Yonsai and Victoria-Regina evolutionary models fit the components of AD Boo and VZ Hya almost equally well, assuming coeval formation, at ages of about 1.75/1.50 Gyr (AD Boo) and 1.25/1.00 Gyr (VZ Hya). BaSTI models, however, predict somewhat different ages for the primary and secondary components. For WZ Oph, the models from all three grids are significantly hotter than observed. A low He content, decreased envelope convection coupled with surface activity, and/or higher interstellar absorption would remove the discrepancy, but its cause has not been definitively identified. Conclusions: We have demonstrated the power of testing and comparing

Rethinking Teacher Evaluation: A Conversation about Statistical Inferences and Value-Added Models

ERIC Educational Resources Information Center

Callister Everson, Kimberlee; Feinauer, Erika; Sudweeks, Richard R.

2013-01-01

In this article, the authors provide a methodological critique of the current standard of value-added modeling forwarded in educational policy contexts as a means of measuring teacher effectiveness. Conventional value-added estimates of teacher quality are attempts to determine to what degree a teacher would theoretically contribute, on average,…

An Ad-Hoc Adaptive Pilot Model for Pitch Axis Gross Acquisition Tasks

NASA Technical Reports Server (NTRS)

Hanson, Curtis E.

2012-01-01

An ad-hoc algorithm is presented for real-time adaptation of the well-known crossover pilot model and applied to pitch axis gross acquisition tasks in a generic fighter aircraft. Off-line tuning of the crossover model to human pilot data gathered in a fixed-based high fidelity simulation is first accomplished for a series of changes in aircraft dynamics to provide expected values for model parameters. It is shown that in most cases, for this application, the traditional crossover model can be reduced to a gain and a time delay. The ad-hoc adaptive pilot gain algorithm is shown to have desirable convergence properties for most types of changes in aircraft dynamics.

The Tetrahedral Zamolodchikov Algebra and the {AdS_5× S^5} S-matrix

NASA Astrophysics Data System (ADS)

Mitev, Vladimir; Staudacher, Matthias; Tsuboi, Zengo

2017-08-01

The S-matrix of the {AdS_5× S^5} string theory is a tensor product of two centrally extended su{(2|2)\\ltimes R^2 S-matrices, each of which is related to the R-matrix of the Hubbard model. The R-matrix of the Hubbard model was first found by Shastry, who ingeniously exploited the fact that, for zero coupling, the Hubbard model can be decomposed into two XX models. In this article, we review and clarify this construction from the AdS/CFT perspective and investigate the implications this has for the {AdS_5× S^5} S-matrix.

Protection of total body water content and absence of hyperthermia despite 2% body mass loss ('voluntary dehydration') in soldiers drinking ad libitum during prolonged exercise in cool environmental conditions.

PubMed

Nolte, Heinrich W; Noakes, Timothy D; van Vuuren, Bernard

2011-11-01

The extent to which humans need to replace fluid losses during exercise remains contentious despite years of focused research. The primary objective was to evaluate ad libitum drinking on hydration status to determine whether body mass loss can be used as an accurate surrogate for changes in total body water (TBW) during exercise. Data were collected during a 14.6-km route march (wet bulb globe temperature of 14.1°C ). 18 subjects with an average age of 26 ± 2.5 (SD) years participated. Their mean ad libitum total fluid intake was 2.1 ± 1.4 litres during the exercise. Predicted sweat rate was 1.289 ± 0.530 l/h. There were no significant changes (p>0.05) in TBW, urine specific gravity or urine osmolality despite an average body mass loss (p<0.05) of 1.3 ± 0.45 kg during the march. Core temperature rose as a function of marching speed and was unrelated to the % change in body mass. This suggests that changes in mass do not accurately predict changes in TBW (r=-0.16) because either the body mass loss during exercise includes losses other than water or there is an endogenous body water source that is released during exercise not requiring replacement during exercise, or both. Ad libitum water replacement between 65% and 70% of sweat losses maintained safe levels of hydration during the experiment. The finding that TBW was protected by ad libitum drinking despite approximately 2% body mass loss suggests that the concept of 'voluntary dehydration' may require revision.

Progressing towards more quantitative analytical pyrolysis of soil organic matter using molecular beam mass spectroscopy of whole soils and added standards

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haddix, Michelle L.; Magrini-Bair, Kim; Evans, Robert J.

Soil organic matter (SOM) is extremely complex. It is composed of hundreds of different organic substances and it has been difficult to quantify these diverse substances in a dynamic-ecosystem functioning standpoint. Analytical pyrolysis has been used to compare chemical differences between soils, but its ability to measure the absolute amount of a specific compound in the soil is still in question. Our objective was to assess whether utilizing pyrolysis-molecular beam mass spectroscopy (py-MBMS) to define the signature of known reference compounds (adenine, indole, palmitic acid, etc.) and biological samples (chitin, fungi, cellulose, etc.) separately and when added to whole soilsmore » it was possible to make py-MBMS more quantitative. Reference compounds, spanning a wide variety of compound categories, and biological samples, expected to be present in SOM, were added to three soils from Colorado, Ohio, and Massachusetts that have varying total C, % clay, and clay type. Py-MBMS, a rapid analysis technique originally developed to analyze complex biomolecules, flash pyrolyzes soil organic matter to form products that are often considered characteristic of the original molecular structure. Samples were pyrolyzed at 550 degrees C by py-MBMS. All samples were weighed and %C and %N determined both before and after pyrolysis to evaluate mass loss, C loss, and N loss for the samples.An average relationship of r2 = 0.76 (P = 0.005) was found for the amount of cellulose added to soil at 25, 50, and 100% of soil C relative to the ion intensity of select mass/charge of the compound.There was a relationship of r2 = 0.93 (P < 0.001) for the amount of indole added to soil at 25, 50, and 100% of soil C and the ion intensity of the associated mass variables (mass/charge). Comparing spectra of pure compounds with the spectra of the compounds added to soil and isolated clay showed that interference could occur based on soil type and compound with the Massachusetts soil with high

Delay-dependent stability and added damping of SDOF real-time dynamic hybrid testing

NASA Astrophysics Data System (ADS)

Chi, Fudong; Wang, Jinting; Jin, Feng

2010-09-01

It is well-recognized that a transfer system response delay that reduces the test stability inevitably exists in real-time dynamic hybrid testing (RTDHT). This paper focuses on the delay-dependent stability and added damping of SDOF systems in RTDHT. The exponential delay term is transferred into a rational fraction by the Padé approximation, and the delay-dependent stability conditions and instability mechanism of SDOF RTDHT systems are investigated by the root locus technique. First, the stability conditions are discussed separately for the cases of stiffness, mass, and damping experimental substructure. The use of root locus plots shows that the added damping effect and instability mechanism for mass are different from those for stiffness. For the stiffness experimental substructure case, the instability results from the inherent mode because of an obvious negative damping effect of the delay. For the mass case, the delay introduces an equivalent positive damping into the inherent mode, and instability occurs at an added high frequency mode. Then, the compound stability condition is investigated for a general case and the results show that the mass ratio may have both upper and lower limits to remain stable. Finally, a high-emulational virtual shaking table model is built to validate the stability conclusions.

An added-mass partition algorithm for fluid–structure interactions of compressible fluids and nonlinear solids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Banks, J.W., E-mail: banksj3@rpi.edu; Henshaw, W.D., E-mail: henshw@rpi.edu; Kapila, A.K., E-mail: kapila@rpi.edu

We describe an added-mass partitioned (AMP) algorithm for solving fluid–structure interaction (FSI) problems involving inviscid compressible fluids interacting with nonlinear solids that undergo large rotations and displacements. The computational approach is a mixed Eulerian–Lagrangian scheme that makes use of deforming composite grids (DCG) to treat large changes in the geometry in an accurate, flexible, and robust manner. The current work extends the AMP algorithm developed in Banks et al. [1] for linearly elasticity to the case of nonlinear solids. To ensure stability for the case of light solids, the new AMP algorithm embeds an approximate solution of a nonlinear fluid–solidmore » Riemann (FSR) problem into the interface treatment. The solution to the FSR problem is derived and shown to be of a similar form to that derived for linear solids: the state on the interface being fundamentally an impedance-weighted average of the fluid and solid states. Numerical simulations demonstrate that the AMP algorithm is stable even for light solids when added-mass effects are large. The accuracy and stability of the AMP scheme is verified by comparison to an exact solution using the method of analytical solutions and to a semi-analytical solution that is obtained for a rotating solid disk immersed in a fluid. The scheme is applied to the simulation of a planar shock impacting a light elliptical-shaped solid, and comparisons are made between solutions of the FSI problem for a neo-Hookean solid, a linearly elastic solid, and a rigid solid. The ability of the approach to handle large deformations is demonstrated for a problem of a high-speed flow past a light, thin, and flexible solid beam.« less

Spatial and temporal distribution of mass loss from the Greenland Ice Sheet since AD 1900.

PubMed

Kjeldsen, Kristian K; Korsgaard, Niels J; Bjørk, Anders A; Khan, Shfaqat A; Box, Jason E; Funder, Svend; Larsen, Nicolaj K; Bamber, Jonathan L; Colgan, William; van den Broeke, Michiel; Siggaard-Andersen, Marie-Louise; Nuth, Christopher; Schomacker, Anders; Andresen, Camilla S; Willerslev, Eske; Kjær, Kurt H

2015-12-17

The response of the Greenland Ice Sheet (GIS) to changes in temperature during the twentieth century remains contentious, largely owing to difficulties in estimating the spatial and temporal distribution of ice mass changes before 1992, when Greenland-wide observations first became available. The only previous estimates of change during the twentieth century are based on empirical modelling and energy balance modelling. Consequently, no observation-based estimates of the contribution from the GIS to the global-mean sea level budget before 1990 are included in the Fifth Assessment Report of the Intergovernmental Panel on Climate Change. Here we calculate spatial ice mass loss around the entire GIS from 1900 to the present using aerial imagery from the 1980s. This allows accurate high-resolution mapping of geomorphic features related to the maximum extent of the GIS during the Little Ice Age at the end of the nineteenth century. We estimate the total ice mass loss and its spatial distribution for three periods: 1900-1983 (75.1 ± 29.4 gigatonnes per year), 1983-2003 (73.8 ± 40.5 gigatonnes per year), and 2003-2010 (186.4 ± 18.9 gigatonnes per year). Furthermore, using two surface mass balance models we partition the mass balance into a term for surface mass balance (that is, total precipitation minus total sublimation minus runoff) and a dynamic term. We find that many areas currently undergoing change are identical to those that experienced considerable thinning throughout the twentieth century. We also reveal that the surface mass balance term shows a considerable decrease since 2003, whereas the dynamic term is constant over the past 110 years. Overall, our observation-based findings show that during the twentieth century the GIS contributed at least 25.0 ± 9.4 millimetres of global-mean sea level rise. Our result will help to close the twentieth-century sea level budget, which remains crucial for evaluating the reliability of models used to

Spatial and temporal distribution of mass loss from the Greenland Ice Sheet since AD 1900

NASA Astrophysics Data System (ADS)

Kjeldsen, Kristian K.; Korsgaard, Niels J.; Bjørk, Anders A.; Khan, Shfaqat A.; Box, Jason E.; Funder, Svend; Larsen, Nicolaj K.; Bamber, Jonathan L.; Colgan, William; van den Broeke, Michiel; Siggaard-Andersen, Marie-Louise; Nuth, Christopher; Schomacker, Anders; Andresen, Camilla S.; Willerslev, Eske; Kjær, Kurt H.

2015-12-01

The response of the Greenland Ice Sheet (GIS) to changes in temperature during the twentieth century remains contentious, largely owing to difficulties in estimating the spatial and temporal distribution of ice mass changes before 1992, when Greenland-wide observations first became available. The only previous estimates of change during the twentieth century are based on empirical modelling and energy balance modelling. Consequently, no observation-based estimates of the contribution from the GIS to the global-mean sea level budget before 1990 are included in the Fifth Assessment Report of the Intergovernmental Panel on Climate Change. Here we calculate spatial ice mass loss around the entire GIS from 1900 to the present using aerial imagery from the 1980s. This allows accurate high-resolution mapping of geomorphic features related to the maximum extent of the GIS during the Little Ice Age at the end of the nineteenth century. We estimate the total ice mass loss and its spatial distribution for three periods: 1900-1983 (75.1 ± 29.4 gigatonnes per year), 1983-2003 (73.8 ± 40.5 gigatonnes per year), and 2003-2010 (186.4 ± 18.9 gigatonnes per year). Furthermore, using two surface mass balance models we partition the mass balance into a term for surface mass balance (that is, total precipitation minus total sublimation minus runoff) and a dynamic term. We find that many areas currently undergoing change are identical to those that experienced considerable thinning throughout the twentieth century. We also reveal that the surface mass balance term shows a considerable decrease since 2003, whereas the dynamic term is constant over the past 110 years. Overall, our observation-based findings show that during the twentieth century the GIS contributed at least 25.0 ± 9.4 millimetres of global-mean sea level rise. Our result will help to close the twentieth-century sea level budget, which remains crucial for evaluating the reliability of models used to

Adiabatic pumping solutions in global AdS

NASA Astrophysics Data System (ADS)

Carracedo, Pablo; Mas, Javier; Musso, Daniele; Serantes, Alexandre

2017-05-01

We construct a family of very simple stationary solutions to gravity coupled to a massless scalar field in global AdS. They involve a constantly rising source for the scalar field at the boundary and thereby we name them pumping solutions. We construct them numerically in D = 4. They are regular and, generically, have negative mass. We perform a study of linear and nonlinear stability and find both stable and unstable branches. In the latter case, solutions belonging to different sub-branches can either decay to black holes or to limiting cycles. This observation motivates the search for non-stationary exactly timeperiodic solutions which we actually construct. We clarify the role of pumping solutions in the context of quasistatic adiabatic quenches. In D = 3 the pumping solutions can be related to other previously known solutions, like magnetic or translationally-breaking backgrounds. From this we derive an analytic expression.

Diffusion and chaos from near AdS 2 horizons

DOE PAGES

Blake, Mike; Donos, Aristomenis

2017-02-03

We calculate the thermal diffusivity D =more » $$\\kappa/c_\\rho$$ and butterfy velocity $$\\upsilon_\\beta$$ in holographic models that flow to $$AdS_2$$ x $R^d$ fixed points in the infra-red. We show that both these quantities are governed by the same irrelevant deformation of $$AdS_2$$ and hence establish a simple relationship between them. When this deformation corresponds to a universal dilaton mode of dimension $$\\Delta$$ = 2 then this relationship is always given by D = $$\\upsilon_B^2$$/(2$$\\pi$$T).« less

The Guinea Pig as a Model for Sporadic Alzheimer’s Disease (AD): The Impact of Cholesterol Intake on Expression of AD-Related Genes

PubMed Central

Ong, Daniel; Wijaya, Linda; Laws, Simon M.; Taddei, Kevin; Newman, Morgan; Lardelli, Michael; Martins, Ralph N.; Verdile, Giuseppe

2013-01-01

We investigated the guinea pig, Cavia porcellus, as a model for Alzheimer’s disease (AD), both in terms of the conservation of genes involved in AD and the regulatory responses of these to a known AD risk factor - high cholesterol intake. Unlike rats and mice, guinea pigs possess an Aβ peptide sequence identical to human Aβ. Consistent with the commonality between cardiovascular and AD risk factors in humans, we saw that a high cholesterol diet leads to up-regulation of BACE1 (β-secretase) transcription and down-regulation of ADAM10 (α-secretase) transcription which should increase release of Aβ from APP. Significantly, guinea pigs possess isoforms of AD-related genes found in humans but not present in mice or rats. For example, we discovered that the truncated PS2V isoform of human PSEN2, that is found at raised levels in AD brains and that increases γ-secretase activity and Aβ synthesis, is not uniquely human or aberrant as previously believed. We show that PS2V formation is up-regulated by hypoxia and a high-cholesterol diet while, consistent with observations in humans, Aβ concentrations are raised in some brain regions but not others. Also like humans, but unlike mice, the guinea pig gene encoding tau, MAPT, encodes isoforms with both three and four microtubule binding domains, and cholesterol alters the ratio of these isoforms. We conclude that AD-related genes are highly conserved and more similar to human than the rat or mouse. Guinea pigs represent a superior rodent model for analysis of the impact of dietary factors such as cholesterol on the regulation of AD-related genes. PMID:23805206

Testing atomic mass models with radioactive beams

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haustein, P.E.

1989-01-01

Significantly increased yields of new or poorly characterized exotic isotopes that lie far from beta-decay stability can be expected when radioactive beams are used to produce these nuclides. Measurements of the masses of these new species are very important. Such measurements are motivated by the general tendency of mass models to diverge from one another upon excursions from the line of beta-stability. Therefore in these regions (where atomic mass data are presently nonexistent or sparse) the models can be tested rigorously to highlight the features that affect the quality of their short-range and long-range extrapolation properties. Selection of systems tomore » study can be guided, in part, by a desire to probe those mass regions where distinctions among mass models are most apparent and where yields of exotic isotopes, produced via radioactive beams, can be optimized. Identification of models in such regions that have good predictive properties will aid materially in guiding the selection of additional experiments which ultimately will provide expansion of the atomic mass database for further refinement of the mass models. 6 refs., 5 figs.« less

Hairy AdS black holes with a toroidal horizon in 4D Einstein-nonlinear σ-model system

NASA Astrophysics Data System (ADS)

Astorino, Marco; Canfora, Fabrizio; Giacomini, Alex; Ortaggio, Marcello

2018-01-01

An exact hairy asymptotically locally AdS black hole solution with a flat horizon in the Einstein-nonlinear sigma model system in (3+1) dimensions is constructed. The ansatz for the nonlinear SU (2) field is regular everywhere and depends explicitly on Killing coordinates, but in such a way that its energy-momentum tensor is compatible with a metric with Killing fields. The solution is characterized by a discrete parameter which has neither topological nor Noether charge associated with it and therefore represents a hair. A U (1) gauge field interacting with Einstein gravity can also be included. The thermodynamics is analyzed. Interestingly, the hairy black hole is always thermodynamically favoured with respect to the corresponding black hole with vanishing Pionic field.

SIMSWASTE-AD - A modelling framework for the environmental assessment of agricultural waste management strategies: Anaerobic digestion.

PubMed

Pardo, Guillermo; Moral, Raúl; Del Prado, Agustín

2017-01-01

On-farm anaerobic digestion (AD) has been promoted due to its improved environmental performance, which is based on a number of life cycle assessments (LCA). However, the influence of site-specific conditions and practices on AD performance is rarely captured in LCA studies and the effects on C and N cycles are often overlooked. In this paper, a new model for AD (SIMS WASTE-AD ) is described in full and tested against a selection of available measured data. Good agreement between modelled and measured values was obtained, reflecting the model capability to predict biogas production (r 2 =0.84) and N mineralization (r 2 =0.85) under a range of substrate mixtures and operational conditions. SIMS WASTE-AD was also used to simulate C and N flows and GHG emissions for a set of scenarios exploring different AD technology levels, feedstock mixtures and climate conditions. The importance of post-digestion emissions and its relationship with the AD performance have been stressed as crucial factors to reduce the net GHG emissions (-75%) but also to enhance digestate fertilizer potential (15%). Gas tight digestate storage with residual biogas collection is highly recommended (especially in temperate to warm climates), as well as those operational conditions that can improve the process efficiency on degrading VS (e.g. thermophilic range, longer hydraulic retention time). Beyond the effects on the manure management stage, SIMS WASTE-AD also aims to help account for potential effects of AD on other stages by providing the C and nutrient flows. While primarily designed to be applied within the SIMS DAIRY modelling framework, it can also interact with other models implemented in integrated approaches. Such system scope assessments are essential for stakeholders and policy makers in order to develop effective strategies for reducing GHG emissions and environmental issues in the agriculture sector. Copyright © 2016 Elsevier B.V. All rights reserved.

Added value of shear-wave elastography for evaluation of breast masses detected with screening US imaging.

PubMed

Lee, Su Hyun; Chang, Jung Min; Kim, Won Hwa; Bae, Min Sun; Seo, Mirinae; Koo, Hye Ryoung; Chu, A Jung; Gweon, Hye Mi; Cho, Nariya; Moon, Woo Kyung

2014-10-01

To evaluate the additional value of shear-wave elastography (SWE) to B-mode ultrasonography (US) and to determine an appropriate guideline for the combined assessment of screening US-detected breast masses. This study was conducted with institutional review board approval, and written informed consent was obtained. From March 2010 to February 2012, B-mode US and SWE were performed in 159 US-detected breast masses before biopsy. For each lesion, Breast Imaging Reporting and Data System (BI-RADS) category on B-mode US images and the maximum stiffness color and elasticity values on SWE images were assessed. A guideline for adding SWE data to B-mode US was developed with the retrospective cohort to improve diagnostic performance in sensitivity and specificity and was validated in a distinct prospective cohort of 207 women prior to biopsy. Twenty-one of 159 masses in the development cohort and 12 of 207 breast masses in the validation cohort were malignant. In the development cohort, when BI-RADS category 4a masses showing a dark blue color or a maximum elasticity value of 30 kPa or less on SWE images were downgraded to category 3, specificity increased from 9.4% (13 of 138) to 59.4% (82 of 138) and 57.2% (79 of 138) (P < .001), respectively, without loss in sensitivity (100% [21 of 21]). In the validation cohort, specificity increased from 17.4% (34 of 195) to 62.1% (121 of 195) and 53.3% (104 of 195) (P < .001) respectively, without loss in sensitivity (91.7% [11 of 12]). The addition of SWE to B-mode US improved diagnostic performance with increased specificity for screening US-detected breast masses. BI-RADS category 4a masses detected at US screening that showed a dark blue color or a maximum elasticity value of 30 kPa or less on SWE images can be safely followed up instead of performing biopsy. © RSNA, 2014.

A Synthetic Model of Mass Persuasion.

ERIC Educational Resources Information Center

Kneupper, Charles W.; Underwood, Willard A.

Mass persuasion involves a message production process which significantly alters or reinforces an attitude, belief, or action of the members of a large, heterogeneous audience. A synthetic communication model for mass persuasion has been constructed which incorporates aspects of several models created to describe the process of effective…

Modeling and optimization of Quality of Service routing in Mobile Ad hoc Networks

NASA Astrophysics Data System (ADS)

Rafsanjani, Marjan Kuchaki; Fatemidokht, Hamideh; Balas, Valentina Emilia

2016-01-01

Mobile ad hoc networks (MANETs) are a group of mobile nodes that are connected without using a fixed infrastructure. In these networks, nodes communicate with each other by forming a single-hop or multi-hop network. To design effective mobile ad hoc networks, it is important to evaluate the performance of multi-hop paths. In this paper, we present a mathematical model for a routing protocol under energy consumption and packet delivery ratio of multi-hop paths. In this model, we use geometric random graphs rather than random graphs. Our proposed model finds effective paths that minimize the energy consumption and maximizes the packet delivery ratio of the network. Validation of the mathematical model is performed through simulation.

Associations between added sugar (solid vs. liquid) intakes, diet quality, and adiposity indicators in Canadian children.

PubMed

Wang, JiaWei; Shang, Lei; Light, Kelly; O'Loughlin, Jennifer; Paradis, Gilles; Gray-Donald, Katherine

2015-08-01

Little is known about the influence of different forms of added sugar intake on diet quality or their association with obesity among youth. Dietary intake was assessed by three 24-h recalls in 613 Canadian children (aged 8-10 years). Added sugars (mean of 3-day intakes) were categorized according to source (solid or liquid). Dietary intake and the Canadian Healthy Eating Index (« HEI-C ») were compared across tertiles of solid and liquid added sugars separately as were adiposity indicators (body mass index (BMI), fat mass (dual-energy X-ray absorptiometry), and waist circumference). Cross-sectional associations were examined in linear regression models adjusting for age, sex, energy intake, and physical activity (7-day accelerometer). Added sugar contributed 12% of total energy intake (204 kcal) on average, of which 78% was from solid sources. Higher consumption of added sugars from either solid or liquid source was associated with higher total energy, lower intake of micronutrients, vegetables and fruit, and lower HEI-C score. Additionally liquid sources were associated with lower intake of dairy products. A 10-g higher consumption of added sugars from liquid sources was associated with 0.4 serving/day lower of vegetables and fruit, 0.4-kg/m(2) higher BMI, a 0.5-kg higher fat mass, and a 0.9-cm higher waist circumference whereas the associations of added sugars from solid sources and adiposity indicators tended to be negative. In conclusion, higher consumption of added sugar from either solid or liquid sources was associated with lower overall diet quality. Adiposity indicators were only positively associated with added sugars from liquid sources.

Quercetin ameliorates Aβ toxicity in Drosophila AD model by modulating cell cycle-related protein expression

PubMed Central

Kong, Yan; Li, Ke; Fu, Tingting; Wan, Chao; Zhang, Dongdong; Song, Hang; Zhang, Yao; Liu, Na; Gan, Zhenji; Yuan, Liudi

2016-01-01

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder characterized by β amyloid (Aβ) deposition and neurofibril tangles. It has been reported that a bioflavonoid, quercetin, could ameliorate AD phenotypes in C. elegans and mice. However, the mechanism underlying the ameliorative effect of quercetin is not fully understood yet. Drosophila models could recapitulate AD-like phenotypes, such as shortened lifespan, impaired locomotive ability as well as defects in learning and memory. So in this study, we investigated the effects of quercetin on AD in Drosophila model and explored the underlying mechanisms. We found quercetin could effectively intervene in AD pathogenesis in vivo. Mechanism study showed quercetin could restore the expression of genes perturbed by Aβ accumulation, such as those involved in cell cycle and DNA replication. Cyclin B, an important cell cycle protein, was chosen to test whether it participated in the AD ameliorative effects of quercetin. We found that cyclin B RNAi in the brain could alleviate AD phenotypes. Taken together, the current study suggested that the neuroprotective effects of quercetin were mediated at least partially by targeting cell cycle-related proteins. PMID:27626494

Shear-wave elastography quantitative assessment of the male breast: added value to distinguish benign and malignant palpable masses.

PubMed

Crombé, Amandine; Hurtevent-Labrot, Gabrielle; Asad-Syed, Maryam; Palussière, Jean; MacGrogan, Gaetan; Kind, Michèle; Ferron, Stéphane

2018-02-01

To evaluate the ability of shear-wave elastography (SWE) to distinguish between benign and malignant palpable masses of the adult male breast. Clinical examination, mammography, B-mode and Doppler ultrasound findings and SWE quantitative parameters were compared in 50 benign lesions (including 40 gynaecomastias) and 15 malignant lesions (invasive ductal carcinomas) from 65 patients who were consecutively addressed for specialized advice at our comprehensive cancer centre. Mean elasticity (El mean), maximum elasticity (El max), El mean of the surrounding fatty tissue and lesion to fat ratio (El ratio) were reported for each patient. Malignant masses displayed significantly higher El mean (p < 0.0001), El max (p < 0.0001) and El ratio (p < 0.0001) compared to benign masses without overlap of values between the two groups. By adding SWE to clinical examination, mammography and ultrasound, all the lesions would have been retrospectively correctly diagnosed as benign or malignant. One false positive could have been downstaged, 14/65 undetermined masses could have been correctly reclassified as 4 malignant and 10 benign lesions, for which biopsies could have consequently been avoided. Evaluation of male breast palpable masses by SWE demonstrates that malignant masses are significantly stiffer lesions and may improve diagnostic management when clinical examination, mammography and conventional ultrasound are doubtful. Advances in knowledge: Quantitative SWE is feasible in male breast and could be of great interest to help classify doubtful lesions after classical clinical and radiological evaluations, probably because of different anatomy and different tumours epidemiology compared with female breast.

Consistency Between Increasing Trends in Added-Sugar Intake and Body Mass Index Among Adults: The Minnesota Heart Survey, 1980–1982 to 2007–2009

PubMed Central

Wang, Huifen; Zhou, Xia; Harnack, Lisa; Luepker, Russell V.

2013-01-01

Objectives. We described 27-year secular trends in added-sugar intake and body mass index (BMI) among Americans aged 25 to 74 years. Methods. The Minnesota Heart Survey (1980–1982 to 2007–2009) is a surveillance study of cardiovascular risk factors among residents of the Minneapolis–St Paul area. We used generalized linear mixed regressions to describe trends in added-sugar intake and BMI by gender and age groups and intake trends by weight status. Results. BMI increased concurrently with added-sugar intake in both genders and all age and weight groups. Percentage of energy intake from added sugar increased by 54% in women between 1980 to 1982 and 2000 to 2002, but declined somewhat in 2007 to 2009; men followed the same pattern (all P < .001). Added-sugar intake was lower among women than men and higher among younger than older adults. BMI in women paralleled added-sugar intake, but men's BMI increased through 2009. Percentage of energy intake from added sugar was similar among weight groups. Conclusions. Limiting added-sugar intake should be part of energy balance strategies in response to the obesity epidemic. PMID:22698050

A fault-tolerant small world topology control model in ad hoc networks for search and rescue

NASA Astrophysics Data System (ADS)

Tan, Mian; Fang, Ling; Wu, Yue; Zhang, Bo; Chang, Bowen; Holme, Petter; Zhao, Jing

2018-02-01

Due to their self-organized, multi-hop and distributed characteristics, ad hoc networks are useful in search and rescue. Topology control models need to be designed for energy-efficient, robust and fast communication in ad hoc networks. This paper proposes a topology control model which specializes for search and rescue-Compensation Small World-Repeated Game (CSWRG)-which integrates mobility models, constructing small world networks and a game-theoretic approach to the allocation of resources. Simulation results show that our mobility models can enhance the communication performance of the constructed small-world networks. Our strategy, based on repeated game, can suppress selfish behavior and compensate agents that encounter selfish or faulty neighbors. This model could be useful for the design of ad hoc communication networks.

Structural models for nickel electrode active mass

NASA Technical Reports Server (NTRS)

Cornilsen, Bahne C.; Karjala, P. J.; Loyselle, P. L.

1987-01-01

Raman spectroscopic data allow one to distinguish nickel electrode active mass, alpha and beta phase materials. Discharges active mass is not isostructural with beta-Ni(OH)2. This is contrary to the generally accepted model for the discharged beta phase of active mass. It is concluded that charged active mass displays a disordered and nonstoichiometric, nonclose packed structure of the R3 bar m, NiOOH structure type. Raman spectral data and x ray diffraction data are analyzed and shown to be consistent with this structural model.

Effectiveness Measures for Cross-Sectional Studies: A Comparison of Value-Added Models and Contextualised Attainment Models

ERIC Educational Resources Information Center

Lenkeit, Jenny

2013-01-01

Educational effectiveness research often appeals to "value-added models (VAM)" to gauge the impact of schooling on student learning net of the effect of student background variables. A huge amount of cross-sectional studies do not, however, meet VAM's requirement for longitudinal data. "Contextualised attainment models (CAM)"…

Hyper-scaling relations in the conformal window from dynamic AdS/QCD

NASA Astrophysics Data System (ADS)

Evans, Nick; Scott, Marc

2014-09-01

Dynamic AdS/QCD is a holographic model of strongly coupled gauge theories with the dynamics included through the running anomalous dimension of the quark bilinear, γ. We apply it to describe the physics of massive quarks in the conformal window of SU(Nc) gauge theories with Nf fundamental flavors, assuming the perturbative two-loop running for γ. We show that to find regular, holographic renormalization group flows in the infrared, the decoupling of the quark flavors at the scale of the mass is important, and enact it through suitable boundary conditions when the flavors become on shell. We can then compute the quark condensate and the mesonic spectrum (Mρ,Mπ,Mσ) and decay constants. We compute their scaling dependence on the quark mass for a number of examples. The model matches perturbative expectations for large quark mass and naïve dimensional analysis (including the anomalous dimensions) for small quark mass. The model allows study of the intermediate regime where there is an additional scale from the running of the coupling, and we present results for the deviation of scalings from assuming only the single scale of the mass.

The dual pathway model of AD/HD: an elaboration of neuro-developmental characteristics.

PubMed

Sonuga-Barke, Edmund J S

2003-11-01

The currently dominant neuro-cognitive model of Attention Deficit Hyperactivity Disorder (AD/HD) presents the condition as executive dysfunction (EDF) underpinned by disturbances in the fronto-dorsal striatal circuit and associated dopaminergic branches (e.g. meso-cortical). In contrast, motivationally-based accounts focus on altered reward processes and implicate fronto-ventral striatal reward circuits and those meso-limbic branches that terminate in the ventral striatum especially the nucleus accumbens. One such account, delay aversion (DEL), presents AD/HD as a motivational style-characterised by attempts to escape or avoid delay-arising from fundamental disturbances in these reward centres. While traditionally regarded as competing, EDF and DEL models have recently been presented as complimentary accounts of two psycho-patho-physiological subtypes of AD/HD with different developmental pathways, underpinned by different cortico-striatal circuits and modulated by different branches of the dopamine system. In the current paper we describe the development of this model in more detail. We elaborate on the neuro-circuitry possibly underpinning these two pathways and explore their developmental significance within a neuro-ecological framework.

New Low-mass Eclipsing Binary Systems in Praesepe Discovered by K2

NASA Astrophysics Data System (ADS)

Gillen, Edward; Hillenbrand, Lynne A.; David, Trevor J.; Aigrain, Suzanne; Rebull, Luisa; Stauffer, John; Cody, Ann Marie; Queloz, Didier

2017-11-01

We present the discovery and characterization of four low-mass (M< 0.6 {M}⊙ ) eclipsing binary (EB) systems in the sub-Gyr old Praesepe open cluster using Kepler/K2 time series photometry and Keck/HIRES spectroscopy. We present a new Gaussian process EB model, GP-EBOP, as well as a method of simultaneously determining effective temperatures and distances for EBs. Three of the reported systems (AD 3814, AD 2615 and AD 1508) are detached and double-lined, and precise solutions are presented for the first two. We determine masses and radii to 1%-3% precision for AD 3814 and to 5%-6% for AD 2615. Together with effective temperatures determined to ˜50 K precision, we test the PARSEC v1.2 and BHAC15 stellar evolution models. Our EB parameters are more consistent with the PARSEC models, primarily because the BHAC15 temperature scale is hotter than our data over the mid-M-dwarf mass range probed. Both ADs 3814 and 2615, which have orbital periods of 6.0 and 11.6 days, are circularized but not synchronized. This suggests that either synchronization proceeds more slowly in fully convective stars than the theory of equilibrium tides predicts, or magnetic braking is currently playing a more important role than tidal forces in the spin evolution of these binaries. The fourth system (AD 3116) comprises a brown dwarf transiting a mid-M-dwarf, which is the first such system discovered in a sub-Gyr open cluster. Finally, these new discoveries increase the number of characterized EBs in sub-Gyr open clusters by 20% (40%) below M< 1.5 M ⊙ (M< 0.6 M ⊙).

Multiplicative effects model with internal standard in mobile phase for quantitative liquid chromatography-mass spectrometry.

PubMed

Song, Mi; Chen, Zeng-Ping; Chen, Yao; Jin, Jing-Wen

2014-07-01

Liquid chromatography-mass spectrometry assays suffer from signal instability caused by the gradual fouling of the ion source, vacuum instability, aging of the ion multiplier, etc. To address this issue, in this contribution, an internal standard was added into the mobile phase. The internal standard was therefore ionized and detected together with the analytes of interest by the mass spectrometer to ensure that variations in measurement conditions and/or instrument have similar effects on the signal contributions of both the analytes of interest and the internal standard. Subsequently, based on the unique strategy of adding internal standard in mobile phase, a multiplicative effects model was developed for quantitative LC-MS assays and tested on a proof of concept model system: the determination of amino acids in water by LC-MS. The experimental results demonstrated that the proposed method could efficiently mitigate the detrimental effects of continuous signal variation, and achieved quantitative results with average relative predictive error values in the range of 8.0-15.0%, which were much more accurate than the corresponding results of conventional internal standard method based on the peak height ratio and partial least squares method (their average relative predictive error values were as high as 66.3% and 64.8%, respectively). Therefore, it is expected that the proposed method can be developed and extended in quantitative LC-MS analysis of more complex systems. Copyright © 2014 Elsevier B.V. All rights reserved.

Chronic Anatabine Treatment Reduces Alzheimer's Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD.

PubMed

Verma, Megha; Beaulieu-Abdelahad, David; Ait-Ghezala, Ghania; Li, Rena; Crawford, Fiona; Mullan, Michael; Paris, Daniel

2015-01-01

Anatabine is a minor tobacco alkaloid, which is also found in plants of the Solanaceae family and displays a chemical structure similarity with nicotine. We have shown previously that anatabine displays some anti-inflammatory properties and reduces microgliosis and tau phosphorylation in a pure mouse model of tauopathy. We therefore investigated the effects of a chronic oral treatment with anatabine in a transgenic mouse model (Tg PS1/APPswe) of Alzheimer's disease (AD) which displays pathological Aβ deposits, neuroinflammation and behavioral deficits. In the elevated plus maze, Tg PS1/APPswe mice exhibited hyperactivity and disinhibition compared to wild-type mice. Six and a half months of chronic oral anatabine treatment, suppressed hyperactivity and disinhibition in Tg PS1/APPswe mice compared to Tg PS1/APPswe receiving regular drinking water. Tg PS1/APPswe mice also elicited profound social interaction and social memory deficits, which were both alleviated by the anatabine treatment. We found that anatabine reduces the activation of STAT3 and NFκB in the vicinity of Aβ deposits in Tg PS1/APPswe mice resulting in a reduction of the expression of some of their target genes including Bace1, iNOS and Cox-2. In addition, a significant reduction in microgliosis and pathological deposition of Aβ was observed in the brain of Tg PS1/APPswe mice treated with anatabine. This is the first study to investigate the impact of chronic anatabine treatment on AD-like pathology and behavior in a transgenic mouse model of AD. Overall, our data show that anatabine reduces β-amyloidosis, neuroinflammation and alleviates some behavioral deficits in Tg PS1/APPswe, supporting further exploration of anatabine as a possible disease modifying agent for the treatment of AD.

Fetal Adrenal Demedullation Lowers Circulating Norepinephrine and Attenuates Growth Restriction but not Reduction of Endocrine Cell Mass in an Ovine Model of Intrauterine Growth Restriction

PubMed Central

Davis, Melissa A.; Macko, Antoni R.; Steyn, Leah V.; Anderson, Miranda J.; Limesand, Sean W.

2015-01-01

Placental insufficiency is associated with fetal hypoglycemia, hypoxemia, and elevated plasma norepinephrine (NE) that become increasingly pronounced throughout the third trimester and contribute to intrauterine growth restriction (IUGR). This study evaluated the effect of fetal adrenal demedullation (AD) on growth and pancreatic endocrine cell mass. Placental insufficiency-induced IUGR was created by exposing pregnant ewes to elevated ambient temperatures during mid-gestation. Treatment groups consisted of control and IUGR fetuses with either surgical sham or AD at 98 days gestational age (dGA; term = 147 dGA), a time-point that precedes IUGR. Samples were collected at 134 dGA. IUGR-sham fetuses were hypoxemic, hypoglycemic, and hypoinsulinemic, and values were similar in IUGR-AD fetuses. Plasma NE concentrations were ~5-fold greater in IUGR-sham compared to control-sham, control-AD, and IUGR-AD fetuses. IUGR-sham and IUGR-AD fetuses weighed less than controls. Compared to IUGR-sham fetuses, IUGR-AD fetuses weighed more and asymmetrical organ growth was absent. Pancreatic β-cell mass and α-cell mass were lower in both IUGR-sham and IUGR-AD fetuses compared to controls, however, pancreatic endocrine cell mass relative to fetal mass was lower in IUGR-AD fetuses. These findings indicate that NE, independently of hypoxemia, hypoglycemia and hypoinsulinemia, influence growth and asymmetry of growth but not pancreatic endocrine cell mass in IUGR fetuses. PMID:25584967

Modelling baryonic effects on galaxy cluster mass profiles

NASA Astrophysics Data System (ADS)

Shirasaki, Masato; Lau, Erwin T.; Nagai, Daisuke

2018-06-01

Gravitational lensing is a powerful probe of the mass distribution of galaxy clusters and cosmology. However, accurate measurements of the cluster mass profiles are limited by uncertainties in cluster astrophysics. In this work, we present a physically motivated model of baryonic effects on the cluster mass profiles, which self-consistently takes into account the impact of baryons on the concentration as well as mass accretion histories of galaxy clusters. We calibrate this model using the Omega500 hydrodynamical cosmological simulations of galaxy clusters with varying baryonic physics. Our model will enable us to simultaneously constrain cluster mass, concentration, and cosmological parameters using stacked weak lensing measurements from upcoming optical cluster surveys.

The Politics and Statistics of Value-Added Modeling for Accountability of Teacher Preparation Programs

ERIC Educational Resources Information Center

Lincove, Jane Arnold; Osborne, Cynthia; Dillon, Amanda; Mills, Nicholas

2014-01-01

Despite questions about validity and reliability, the use of value-added estimation methods has moved beyond academic research into state accountability systems for teachers, schools, and teacher preparation programs (TPPs). Prior studies of value-added measurement for TPPs test the validity of researcher-designed models and find that measuring…

Investigating added value of regional climate modeling in North American winter storm track simulations

NASA Astrophysics Data System (ADS)

Poan, E. D.; Gachon, P.; Laprise, R.; Aider, R.; Dueymes, G.

2018-03-01

Extratropical Cyclone (EC) characteristics depend on a combination of large-scale factors and regional processes. However, the latter are considered to be poorly represented in global climate models (GCMs), partly because their resolution is too coarse. This paper describes a framework using possibilities given by regional climate models (RCMs) to gain insight into storm activity during winter over North America (NA). Recent past climate period (1981-2005) is considered to assess EC activity over NA using the NCEP regional reanalysis (NARR) as a reference, along with the European reanalysis ERA-Interim (ERAI) and two CMIP5 GCMs used to drive the Canadian Regional Climate Model—version 5 (CRCM5) and the corresponding regional-scale simulations. While ERAI and GCM simulations show basic agreement with NARR in terms of climatological storm track patterns, detailed bias analyses show that, on the one hand, ERAI presents statistically significant positive biases in terms of EC genesis and therefore occurrence while capturing their intensity fairly well. On the other hand, GCMs present large negative intensity biases in the overall NA domain and particularly over NA eastern coast. In addition, storm occurrence over the northwestern topographic regions is highly overestimated. When the CRCM5 is driven by ERAI, no significant skill deterioration arises and, more importantly, all storm characteristics near areas with marked relief and over regions with large water masses are significantly improved with respect to ERAI. Conversely, in GCM-driven simulations, the added value contributed by CRCM5 is less prominent and systematic, except over western NA areas with high topography and over the Western Atlantic coastlines where the most frequent and intense ECs are located. Despite this significant added-value on seasonal-mean characteristics, a caveat is raised on the RCM ability to handle storm temporal `seriality', as a measure of their temporal variability at a given

Adiabatic Mass Loss Model in Binary Stars

NASA Astrophysics Data System (ADS)

Ge, H. W.

2012-07-01

Rapid mass transfer process in the interacting binary systems is very complicated. It relates to two basic problems in the binary star evolution, i.e., the dynamically unstable Roche-lobe overflow and the common envelope evolution. Both of the problems are very important and difficult to be modeled. In this PhD thesis, we focus on the rapid mass loss process of the donor in interacting binary systems. The application to the criterion of dynamically unstable mass transfer and the common envelope evolution are also included. Our results based on the adiabatic mass loss model could be used to improve the binary evolution theory, the binary population synthetic method, and other related aspects. We build up the adiabatic mass loss model. In this model, two approximations are included. The first one is that the energy generation and heat flow through the stellar interior can be neglected, hence the restructuring is adiabatic. The second one is that he stellar interior remains in hydrostatic equilibrium. We model this response by constructing model sequences, beginning with a donor star filling its Roche lobe at an arbitrary point in its evolution, holding its specific entropy and composition profiles fixed. These approximations are validated by the comparison with the time-dependent binary mass transfer calculations and the polytropic model for low mass zero-age main-sequence stars. In the dynamical time scale mass transfer, the adiabatic response of the donor star drives it to expand beyond its Roche lobe, leading to runaway mass transfer and the formation of a common envelope with its companion star. For donor stars with surface convection zones of any significant depth, this runaway condition is encountered early in mass transfer, if at all; but for main sequence stars with radiative envelopes, it may be encountered after a prolonged phase of thermal time scale mass transfer, so-called delayed dynamical instability. We identify the critical binary mass ratio for the

Independent effects of adding weight and inertia on balance during quiet standing

PubMed Central

2012-01-01

Background Human balance during quiet standing is influenced by adding mass to the body with a backpack, with symmetrically-applied loads to the trunk, or with obesity. Adding mass to the body increases both the weight and inertia of the body, which theoretically could provide counteracting effects on body dynamics and balance. Understanding the independent effects of adding weight and inertia on balance may provide additional insight into human balance that could lead to novel advancements in balance training and rehabilitation. Therefore, the purpose of this study was to investigate the independent effects of adding weight and inertia on balance during quiet standing. Methods Sixteen normal-weight young adult participants stood as still as possible on a custom-built backboard apparatus under four experimental conditions: baseline, added inertia only, added weight only, and added inertia and weight. Results Adding inertia by itself had no measurable effect on center of pressure movement or backboard movement. Adding weight by itself increased center of pressure movement (indicated greater effort by the postural control system to stand as still as possible) and backboard movement (indicating a poorer ability of the body to stand as still as possible). Adding inertia and weight at the same time increased center of pressure movement but did not increase backboard movement compared to the baseline condition. Conclusions Adding inertia and adding weight had different effects on balance. Adding inertia by itself had no effect on balance. Adding weight by itself had a negative effect on balance. When adding inertia and weight at the same time, the added inertia appeared to lessen (but did not eliminate) the negative effect of adding weight on balance. These results improve our fundamental understanding of how added mass influences human balance. PMID:22507125

Independent effects of adding weight and inertia on balance during quiet standing.

PubMed

Costello, Kerry Elizabeth; Matrangola, Sara Louise; Madigan, Michael Lawrence

2012-04-16

Human balance during quiet standing is influenced by adding mass to the body with a backpack, with symmetrically-applied loads to the trunk, or with obesity. Adding mass to the body increases both the weight and inertia of the body, which theoretically could provide counteracting effects on body dynamics and balance. Understanding the independent effects of adding weight and inertia on balance may provide additional insight into human balance that could lead to novel advancements in balance training and rehabilitation. Therefore, the purpose of this study was to investigate the independent effects of adding weight and inertia on balance during quiet standing. Sixteen normal-weight young adult participants stood as still as possible on a custom-built backboard apparatus under four experimental conditions: baseline, added inertia only, added weight only, and added inertia and weight. Adding inertia by itself had no measurable effect on center of pressure movement or backboard movement. Adding weight by itself increased center of pressure movement (indicated greater effort by the postural control system to stand as still as possible) and backboard movement (indicating a poorer ability of the body to stand as still as possible). Adding inertia and weight at the same time increased center of pressure movement but did not increase backboard movement compared to the baseline condition. Adding inertia and adding weight had different effects on balance. Adding inertia by itself had no effect on balance. Adding weight by itself had a negative effect on balance. When adding inertia and weight at the same time, the added inertia appeared to lessen (but did not eliminate) the negative effect of adding weight on balance. These results improve our fundamental understanding of how added mass influences human balance.

Ocular Changes in TgF344-AD Rat Model of Alzheimer's Disease

PubMed Central

Tsai, Yuchun; Lu, Bin; Ljubimov, Alexander V.; Girman, Sergey; Ross-Cisneros, Fred N.; Sadun, Alfredo A.; Svendsen, Clive N.; Cohen, Robert M.; Wang, Shaomei

2014-01-01

Purpose. Alzheimer's disease (AD) is the most common neurodegenerative disorder characterized by progressive decline in learning, memory, and executive functions. In addition to cognitive and behavioral deficits, vision disturbances have been reported in early stage of AD, well before the diagnosis is clearly established. To further investigate ocular abnormalities, a novel AD transgenic rat model was analyzed. Methods. Transgenic (Tg) rats (TgF344-AD) heterozygous for human mutant APPswe/PS1ΔE9 and age-matched wild type (WT) rats, as well as 20 human postmortem retinal samples from both AD and healthy donors were used. Visual function in the rodent was analyzed using the optokinetic response. Immunohistochemistry on retinal and brain sections was used to detect various markers including amyloid-β (Aβ) plaques. Results. As expected, Aβ plaques were detected in the hippocampus, cortex, and retina of Tg rats. Plaque-like structures were also found in two AD human whole-mount retinas. The choroidal thickness was significantly reduced in both Tg rat and in AD human eyes when compared with age-matched controls. Tg rat eyes also showed hypertrophic retinal pigment epithelial cells, inflammatory cells, and upregulation of complement factor C3. Although visual acuity was lower in Tg than in WT rats, there was no significant difference in the retinal ganglion cell number and retinal vasculature. Conclusions. Further studies are needed to elucidate the significance and mechanisms of this pathological change and luminance threshold recording from the superior colliculus. PMID:24398104

Liquid chromatography-tandem mass spectrometry method for determination of panel of neurotransmitters in cerebrospinal fluid from the rat model for tauopathy.

PubMed

Kovac, Andrej; Somikova, Zuzana; Zilka, Norbert; Novak, Michal

2014-02-01

Alzheimer's disease (AD) is still being recognized today as an unmet medical need. Currently, there is no cure and early preclinical diagnostic assay available for AD. Therefore much attention is now being directed at the development of novel methods for quantitative determination of AD biomarkers in the cerebrospinal fluid (CSF). Here, we describe the liquid chromatography-tandem mass spectrometry method for determination of 5-hydroxytryptamine (SER), 5-hydroxyindoleacetic acid (5-HIAA), homovanilic acid (HVA), noradrenaline (NADR), adrenaline (ADR), dopamine (DA), glutamic acid (Glu), γ-aminobutyric acid (GABA), 3,4-dihydroxyphenylacetic acid (DOPAC) and histamine (HIS) in cerebrospinal fluid (CSF) from the rat model for human tauopathy. The benzoyl chloride was used as pre-column derivatization reagents. Neurotransmitters and metabolites were analysed on ultra performance liquid chromatography (UPLC) on C18 column in combination with tandem mass spectrometry. The method is simple, highly sensitive and showed excellent linearity with regression coefficients higher than 0.99. The accuracy was in a range of 93-113% for all analytes. The inter-day precision (n=5 days), expressed as %RSD, was in a range 2-10% for all analytes. Using this method we detected significant changes of CSF levels of two important neurotransmitters/metabolites, ADR and 5-HIAA, which correlates with progression of neurodegeneration in our animal model. © 2013 Published by Elsevier B.V.

Testing the uniqueness of mass models using gravitational lensing

NASA Astrophysics Data System (ADS)

Walls, Levi; Williams, Liliya L. R.

2018-06-01

The positions of images produced by the gravitational lensing of background-sources provide insight to lens-galaxy mass distributions. Simple elliptical mass density profiles do not agree well with observations of the population of known quads. It has been shown that the most promising way to reconcile this discrepancy is via perturbations away from purely elliptical mass profiles by assuming two super-imposed, somewhat misaligned mass distributions: one is dark matter (DM), the other is a stellar distribution. In this work, we investigate if mass modelling of individual lenses can reveal if the lenses have this type of complex structure, or simpler elliptical structure. In other words, we test mass model uniqueness, or how well an extended source lensed by a non-trivial mass distribution can be modeled by a simple elliptical mass profile. We used the publicly-available lensing software, Lensmodel, to generate and numerically model gravitational lenses and “observed” image positions. We then compared “observed” and modeled image positions via root mean square (RMS) of their difference. We report that, in most cases, the RMS is ≤0.05‧‧ when averaged over an extended source. Thus, we show it is possible to fit a smooth mass model to a system that contains a stellar-component with varying levels of misalignment with a DM-component, and hence mass modelling cannot differentiate between simple elliptical versus more complex lenses.

Strategies for fitting nonlinear ecological models in R, AD Model Builder, and BUGS

USGS Publications Warehouse

Bolker, Benjamin M.; Gardner, Beth; Maunder, Mark; Berg, Casper W.; Brooks, Mollie; Comita, Liza; Crone, Elizabeth; Cubaynes, Sarah; Davies, Trevor; de Valpine, Perry; Ford, Jessica; Gimenez, Olivier; Kéry, Marc; Kim, Eun Jung; Lennert-Cody, Cleridy; Magunsson, Arni; Martell, Steve; Nash, John; Nielson, Anders; Regentz, Jim; Skaug, Hans; Zipkin, Elise

2013-01-01

1. Ecologists often use nonlinear fitting techniques to estimate the parameters of complex ecological models, with attendant frustration. This paper compares three open-source model fitting tools and discusses general strategies for defining and fitting models. 2. R is convenient and (relatively) easy to learn, AD Model Builder is fast and robust but comes with a steep learning curve, while BUGS provides the greatest flexibility at the price of speed. 3. Our model-fitting suggestions range from general cultural advice (where possible, use the tools and models that are most common in your subfield) to specific suggestions about how to change the mathematical description of models to make them more amenable to parameter estimation. 4. A companion web site (https://groups.nceas.ucsb.edu/nonlinear-modeling/projects) presents detailed examples of application of the three tools to a variety of typical ecological estimation problems; each example links both to a detailed project report and to full source code and data.

The Black Hole Firewall and Top-Down Constructions of AdS/CFT

NASA Astrophysics Data System (ADS)

Almheiri, Ahmed Eid Khamis Thani

In the first part of this dissertation we argue that the following statements cannot be all true: (i) Black hole formation and evaporation is a unitary process as viewed by external observers, (ii) Physics outside some microscopic distance away from the event horizon is described by local effective quantum field theory, (iii) A black hole is a quantum system with a finite number of states given by the exponential of the Bekenstein Hawking entropy, and (iv) An infalling observer's experience in the vicinity of the horizon is well described by local effective quantum field theory in the infalling reference frame. We argue that the most conservative resolution is that an infalling observer will see drastic violations of effective field theory far away from the singularity, and encounter high energy quanta, a firewall, just behind the black hole event horizon. We address counter proposals to the firewall which involve, in one way or another, radical modifications of quantum mechanics or locality, and argue that they are unsatisfactory in their current formulation. We conclude this part with an investigation into the existence of firewalls in the two dimensional Einstein-dilaton gravity model of CGHS. We find that black holes in such models do not develop firewalls, but rather evaporate down to form small mass remnants. We elaborate on why this is inevitable in two dimensions and argue against a similar conclusion in higher dimensions. In the second part of this dissertation we construct AdS2 and AdS3 magnetic brane solutions within the abelian truncations of AdS4 x orbifolded S7 and AdS5 x S5 supergravity. We find a class of supersymmetric solutions of the bulk theory to assure stability. We perform a preliminary analysis demonstrating the stability of some nonsupersymmetric embeddings. We identify the dual field theory and compare the thermal entropies across the duality. We end with an investigatation into the effects of backreaction on holography in AdS2. We study a

A new model integrating short- and long-term aging of copper added to soils

PubMed Central

Zeng, Saiqi; Li, Jumei; Wei, Dongpu

2017-01-01

Aging refers to the processes by which the bioavailability/toxicity, isotopic exchangeability, and extractability of metals added to soils decline overtime. We studied the characteristics of the aging process in copper (Cu) added to soils and the factors that affect this process. Then we developed a semi-mechanistic model to predict the lability of Cu during the aging process with descriptions of the diffusion process using complementary error function. In the previous studies, two semi-mechanistic models to separately predict short-term and long-term aging of Cu added to soils were developed with individual descriptions of the diffusion process. In the short-term model, the diffusion process was linearly related to the square root of incubation time (t1/2), and in the long-term model, the diffusion process was linearly related to the natural logarithm of incubation time (lnt). Both models could predict short-term or long-term aging processes separately, but could not predict the short- and long-term aging processes by one model. By analyzing and combining the two models, we found that the short- and long-term behaviors of the diffusion process could be described adequately using the complementary error function. The effect of temperature on the diffusion process was obtained in this model as well. The model can predict the aging process continuously based on four factors—soil pH, incubation time, soil organic matter content and temperature. PMID:28820888

Geometry and supersymmetry of heterotic warped flux AdS backgrounds

NASA Astrophysics Data System (ADS)

Beck, S.; Gutowski, J.; Papadopoulos, G.

2015-07-01

We classify the geometries of the most general warped, flux AdS backgrounds of heterotic supergravity up to two loop order in sigma model perturbation theory. We show under some mild assumptions that there are no AdS n backgrounds with n ≠ 3. Moreover the warp factor of AdS3 backgrounds is constant, the geometry is a product AdS 3 × M 7 and such solutions preserve, 2, 4, 6 and 8 supersymmetries. The geometry of M 7 has been specified in all cases. For 2 supersymmetries, it has been found that M 7 admits a suitably restricted G 2 structure. For 4 supersymmetries, M 7 has an SU(3) structure and can be described locally as a circle fibration over a 6-dimensional KT manifold. For 6 and 8 supersymmetries, M 7 has an SU(2) structure and can be described locally as a S 3 fibration over a 4-dimensional manifold which either has an anti-self dual Weyl tensor or a hyper-Kähler structure, respectively. We also demonstrate a new Lichnerowicz type theorem in the presence of α' corrections.

Psychological heterogeneity in AD/HD--a dual pathway model of behaviour and cognition.

PubMed

Sonuga-Barke, Edmund J S

2002-03-10

Psychological accounts have characterised attention-deficit/hyperactivity disorder (AD/HD) as either a neuro-cognitive disorder of regulation or a motivational style. Poor inhibitory control is thought to underpin AD/HD children's dysregulation while delay aversion is a dominant characteristic of their motivational style. A recent 'head to head' study of these two accounts suggest that delay aversion and poor inhibitory control are independent co-existing characteristics of AD/HD (combined type). In the present paper we build on these findings to propose a dual pathway model of AD/HD that recognises two quite distinct sub-types of the disorder. In one AD/HD is the result of the dysregulation of action and thought resulting from poor inhibitory control associated with the meso-cortical branch of the dopamine system projecting in the cortical control centres (e.g. pre-frontal cortex). In the other AD/HD is a motivational style characterised by an altered delay of reward gradient linked to the meso-limbic dopamine branch associated with the reward circuits (e.g. nucleus accumbens). The two pathways are further distinguished at the levels of symptoms, cognitive and motivation profiles and genetic and non-genetic origins.

Chronic Anatabine Treatment Reduces Alzheimer’s Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD

PubMed Central

Verma, Megha; Beaulieu-Abdelahad, David; Ait-Ghezala, Ghania; Li, Rena; Crawford, Fiona; Mullan, Michael; Paris, Daniel

2015-01-01

Anatabine is a minor tobacco alkaloid, which is also found in plants of the Solanaceae family and displays a chemical structure similarity with nicotine. We have shown previously that anatabine displays some anti-inflammatory properties and reduces microgliosis and tau phosphorylation in a pure mouse model of tauopathy. We therefore investigated the effects of a chronic oral treatment with anatabine in a transgenic mouse model (Tg PS1/APPswe) of Alzheimer’s disease (AD) which displays pathological Aβ deposits, neuroinflammation and behavioral deficits. In the elevated plus maze, Tg PS1/APPswe mice exhibited hyperactivity and disinhibition compared to wild-type mice. Six and a half months of chronic oral anatabine treatment, suppressed hyperactivity and disinhibition in Tg PS1/APPswe mice compared to Tg PS1/APPswe receiving regular drinking water. Tg PS1/APPswe mice also elicited profound social interaction and social memory deficits, which were both alleviated by the anatabine treatment. We found that anatabine reduces the activation of STAT3 and NFκB in the vicinity of Aβ deposits in Tg PS1/APPswe mice resulting in a reduction of the expression of some of their target genes including Bace1, iNOS and Cox-2. In addition, a significant reduction in microgliosis and pathological deposition of Aβ was observed in the brain of Tg PS1/APPswe mice treated with anatabine. This is the first study to investigate the impact of chronic anatabine treatment on AD-like pathology and behavior in a transgenic mouse model of AD. Overall, our data show that anatabine reduces β-amyloidosis, neuroinflammation and alleviates some behavioral deficits in Tg PS1/APPswe, supporting further exploration of anatabine as a possible disease modifying agent for the treatment of AD. PMID:26010758

Quantum spectral curve for the η-deformed AdS5 × S5 superstring

NASA Astrophysics Data System (ADS)

Klabbers, Rob; van Tongeren, Stijn J.

2017-12-01

The spectral problem for the AdS5 ×S5 superstring and its dual planar maximally supersymmetric Yang-Mills theory can be efficiently solved through a set of functional equations known as the quantum spectral curve. We discuss how the same concepts apply to the η-deformed AdS5 ×S5 superstring, an integrable deformation of the AdS5 ×S5 superstring with quantum group symmetry. This model can be viewed as a trigonometric version of the AdS5 ×S5 superstring, like the relation between the XXZ and XXX spin chains, or the sausage and the S2 sigma models for instance. We derive the quantum spectral curve for the η-deformed string by reformulating the corresponding ground-state thermodynamic Bethe ansatz equations as an analytic Y system, and map this to an analytic T system which upon suitable gauge fixing leads to a Pμ system - the quantum spectral curve. We then discuss constraints on the asymptotics of this system to single out particular excited states. At the spectral level the η-deformed string and its quantum spectral curve interpolate between the AdS5 ×S5 superstring and a superstring on "mirror" AdS5 ×S5, reflecting a more general relationship between the spectral and thermodynamic data of the η-deformed string. In particular, the spectral problem of the mirror AdS5 ×S5 string, and the thermodynamics of the undeformed AdS5 ×S5 string, are described by a second rational limit of our trigonometric quantum spectral curve, distinct from the regular undeformed limit.

Aspects of warped AdS3/CFT2 correspondence

NASA Astrophysics Data System (ADS)

Chen, Bin; Zhang, Jia-Ju; Zhang, Jian-Dong; Zhong, De-Liang

2013-04-01

In this paper we apply the thermodynamics method to investigate the holographic pictures for the BTZ black hole, the spacelike and the null warped black holes in three-dimensional topologically massive gravity (TMG) and new massive gravity (NMG). Even though there are higher derivative terms in these theories, the thermodynamics method is still effective. It gives consistent results with the ones obtained by using asymptotical symmetry group (ASG) analysis. In doing the ASG analysis we develop a brute-force realization of the Barnich-Brandt-Compere formalism with Mathematica code, which also allows us to calculate the masses and the angular momenta of the black holes. In particular, we propose the warped AdS3/CFT2 correspondence in the new massive gravity, which states that quantum gravity in the warped spacetime could holographically dual to a two-dimensional CFT with {c_R}={c_L}=24 /{Gm{β^2√{{2( {21-4{β^2}} )}}}}.

Impaired attention in the 3xTgAD mouse model of Alzheimer's disease: rescue by donepezil (Aricept).

PubMed

Romberg, Carola; Mattson, Mark P; Mughal, Mohamed R; Bussey, Timothy J; Saksida, Lisa M

2011-03-02

Several mouse models of Alzheimer's disease (AD) with abundant β-amyloid and/or aberrantly phosphorylated tau develop memory impairments. However, multiple non-mnemonic cognitive domains such as attention and executive control are also compromised early in AD individuals. Currently, it is unclear whether mutations in the β-amyloid precursor protein (APP) and tau are sufficient to cause similar, AD-like attention deficits in mouse models of the disease. To address this question, we tested 3xTgAD mice (which express APPswe, PS1M146V, and tauP301L mutations) and wild-type control mice on a newly developed touchscreen-based 5-choice serial reaction time test of attention and response control. The 3xTgAD mice attended less accurately to short, spatially unpredictable stimuli when the attentional demand of the task was high, and also showed a general tendency to make more perseverative responses than wild-type mice. The attentional impairment of 3xTgAD mice was comparable to that of AD patients in two aspects: first, although 3xTgAD mice initially responded as accurately as wild-type mice, they subsequently failed to sustain their attention over the duration of the task; second, the ability to sustain attention was enhanced by the cholinesterase inhibitor donepezil (Aricept). These findings demonstrate that familial AD mutations not only affect memory, but also cause significant impairments in attention, a cognitive domain supported by the prefrontal cortex and its afferents. Because attention deficits are likely to affect memory encoding and other cognitive abilities, our findings have important consequences for the assessment of disease mechanisms and therapeutics in animal models of AD.

Sex steroid levels and AD-like pathology in 3xTgAD mice

PubMed Central

Ma, Chunqi; Taves, Matthew D.; Soma, Kiran K.; Mufson, Elliott J.

2014-01-01

Decreases in testosterone (T) and 17β-oestradiol (E2) are associated with an increased risk for Alzheimer's disease (AD), which has been attributed to an increase in beta amyloid (Aβ) and tau pathologic lesions. While recent studies have used transgenic animal models to test the effects of sex steroid manipulations on AD-like pathology, virtually none have systematically characterised the associations between AD lesions and sex steroid levels in the blood or brain in any mutant model. The present study evaluated age-related changes in T and E2 concentrations, as well as androgen receptor (AR) and oestrogen receptor (ER) α and β expression, in brain regions displaying AD pathology in intact male and female 3xTgAD and non-transgenic (ntg) mice. We report for the first time that circulating and brain T levels significantly increase in male 3xTgAD mice with age, but without changes in AR-immunoreactive (ir) cell number in either the hippocampal CA1 or medial amygdala. The age-related increase in hippocampal T levels correlated positively with increases in the conformational tau isoform, Alz50. These data suggest that the over-expression of human tau may up regulate the hypothalamic-pituitary-gonadal axis in these mice. Although circulating and brain E2 levels remained stable with age in both male and female 3xTgAD and ntg mice, ER-ir cell number in the hippocampus and medial amygdala decreased with age in female transgenic mice. Further, E2 levels were significantly higher in the hippocampus than in serum, suggesting local production of E2. Although triple transgenic mice mimic AD-like pathology, they do not fully replicate changes in human sex steroid levels, and may not be the best model for studying the effects of sex steroids on AD lesions. PMID:22889357

String in AdS black hole: A thermo field dynamic approach

NASA Astrophysics Data System (ADS)

Cantcheff, M. Botta; Gadelha, Alexandre L.; Marchioro, Dáfni F. Z.; Nedel, Daniel Luiz

2012-10-01

Based on Maldacena’s description of an eternal anti-de Sitter (AdS) black hole, we reassess the thermo field dynamics (TFD) formalism in the context of the AdS/CFT correspondence. The model studied here involves the maximally extended AdS-Schwarschild solution and two (noninteracting) copies of the conformal field theory (CFT) associated to the global AdS spacetime, along with an extension of the string by imposing natural gluing conditions in the horizon. We show that the gluing conditions in the horizon define a string boundary state which is identified with the TFD thermal vacuum, globally defined in the Kruskal extension of the AdS black hole. We emphasize the connection of this picture with unitary SU(1,1) TFD formulation, and we show that information about the bulk and the conformal boundary is present in the SU(1,1) parameters. Using the unitary SU(1,1) TFD formulation, a canonical prescription for calculating the world sheet real time thermal Green’s function is made, and the entropy associated with the entanglement of the two CFT’s is calculated.

ADIABATIC MASS LOSS IN BINARY STARS. II. FROM ZERO-AGE MAIN SEQUENCE TO THE BASE OF THE GIANT BRANCH

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ge, Hongwei; Chen, Xuefei; Han, Zhanwen

2015-10-10

In the limit of extremely rapid mass transfer, the response of a donor star in an interacting binary becomes asymptotically one of adiabatic expansion. We survey here adiabatic mass loss from Population I stars (Z = 0.02) of mass 0.10 M{sub ⊙}–100 M{sub ⊙} from the zero-age main sequence to the base of the giant branch, or to central hydrogen exhaustion for lower main sequence stars. The logarithmic derivatives of radius with respect to mass along adiabatic mass-loss sequences translate into critical mass ratios for runaway (dynamical timescale) mass transfer, evaluated here under the assumption of conservative mass transfer. Formore » intermediate- and high-mass stars, dynamical mass transfer is preceded by an extended phase of thermal timescale mass transfer as the star is stripped of most of its envelope mass. The critical mass ratio q{sub ad} (throughout this paper, we follow the convention of defining the binary mass ratio as q ≡ M{sub donor}/M{sub accretor}) above which this delayed dynamical instability occurs increases with advancing evolutionary age of the donor star, by ever-increasing factors for more massive donors. Most intermediate- or high-mass binaries with nondegenerate accretors probably evolve into contact before manifesting this instability. As they approach the base of the giant branch, however, and begin developing a convective envelope, q{sub ad} plummets dramatically among intermediate-mass stars, to values of order unity, and a prompt dynamical instability occurs. Among low-mass stars, the prompt instability prevails throughout main sequence evolution, with q{sub ad} declining with decreasing mass, and asymptotically approaching q{sub ad} = 2/3, appropriate to a classical isentropic n = 3/2 polytrope. Our calculated q{sub ad} values agree well with the behavior of time-dependent models by Chen and Han of intermediate-mass stars initiating mass transfer in the Hertzsprung gap. Application of our results to cataclysmic variables, as

Vibration-based monitoring to detect mass changes in satellites

NASA Astrophysics Data System (ADS)

Maji, Arup; Vernon, Breck

2012-04-01

Vibration-based structural health monitoring could be a useful form of determining the health and safety of space structures. A particular concern is the possibility of a foreign object that attaches itself to a satellite in orbit for adverse reasons. A frequency response analysis was used to determine the changes in mass and moment of inertia of the space structure based on a change in the natural frequencies of the structure or components of the structure. Feasibility studies were first conducted on a 7 in x 19 in aluminum plate with various boundary conditions. Effect of environmental conditions on the frequency response was determined. The baseline frequency response for the plate was then used as the basis for detection of the addition, and possibly the location, of added masses on the plate. The test results were compared to both analytical solutions and finite element models created in SAP2000. The testing was subsequently expanded to aluminum alloy satellite panels and a mock satellite with dummy payloads. Statistical analysis was conducted on variations of frequency due to added mass and thermal changes to determine the threshold of added mass that can be detected.

Value-Added Model (VAM) Research for Educational Policy: Framing the Issue

ERIC Educational Resources Information Center

Amrein-Beardsley, Audrey; Collins, Clarin; Polasky, Sarah A.; Sloat, Edward F.

2013-01-01

In this manuscript, the guest editors of the EPAA Special Issue on "Value-Added Model (VAM) Research for Educational Policy" (1) introduce the background and policy context surrounding the increased use of VAMs for teacher evaluation and accountability purposes across the United States; (2) summarize the five research papers and one…

Adding Insult to Imagery? Art Education and Censorship

ERIC Educational Resources Information Center

Sweeny, Robert W.

2007-01-01

The "Adding Insult to Imagery? Artistic Responses to Censorship and Mass-Media" exhibition opened in January 16, 2006, Kipp Gallery on the Indiana University of Pennsylvania campus. Eleven gallery-based works, 9 videos, and 10 web-based artworks comprised the show; each dealt with the relationship between censorship and mass mediated…

Nuclear binding energy using semi empirical mass formula

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ankita,, E-mail: ankitagoyal@gmail.com; Suthar, B.

2016-05-06

In the present communication, semi empirical mass formula using the liquid drop model has been presented. Nuclear binding energies are calculated using semi empirical mass formula with various constants given by different researchers. We also compare these calculated values with experimental data and comparative study for finding suitable constants is added using the error plot. The study is extended to find the more suitable constant to reduce the error.

Light-meson masses in an unquenched quark model

NASA Astrophysics Data System (ADS)

Chen, Xiaoyun; Ping, Jialun; Roberts, Craig D.; Segovia, Jorge

2018-05-01

We perform a coupled-channels calculation of the masses of light mesons with the quantum numbers I JP =-, (I ,J )=0 , 1, by including q q ¯ and (q q ¯)2 components in a nonrelativistic chiral quark model. The coupling between two- and four-quark configurations is realized through a 3P0 quark-pair creation model. With the usual form of this operator, the mass shifts are large and negative, an outcome which raises serious issues of validity for the quenched quark model. Herein, therefore, we introduce some improvements of the 3P0 operator in order to reduce the size of the mass shifts. By introducing two simple factors, physically well motivated, the coupling between q q ¯ and (q q ¯)2 components is weakened, producing mass shifts that are around 10%-20% of hadron bare masses.

Validating neural-network refinements of nuclear mass models

NASA Astrophysics Data System (ADS)

Utama, R.; Piekarewicz, J.

2018-01-01

Background: Nuclear astrophysics centers on the role of nuclear physics in the cosmos. In particular, nuclear masses at the limits of stability are critical in the development of stellar structure and the origin of the elements. Purpose: We aim to test and validate the predictions of recently refined nuclear mass models against the newly published AME2016 compilation. Methods: The basic paradigm underlining the recently refined nuclear mass models is based on existing state-of-the-art models that are subsequently refined through the training of an artificial neural network. Bayesian inference is used to determine the parameters of the neural network so that statistical uncertainties are provided for all model predictions. Results: We observe a significant improvement in the Bayesian neural network (BNN) predictions relative to the corresponding "bare" models when compared to the nearly 50 new masses reported in the AME2016 compilation. Further, AME2016 estimates for the handful of impactful isotopes in the determination of r -process abundances are found to be in fairly good agreement with our theoretical predictions. Indeed, the BNN-improved Duflo-Zuker model predicts a root-mean-square deviation relative to experiment of σrms≃400 keV. Conclusions: Given the excellent performance of the BNN refinement in confronting the recently published AME2016 compilation, we are confident of its critical role in our quest for mass models of the highest quality. Moreover, as uncertainty quantification is at the core of the BNN approach, the improved mass models are in a unique position to identify those nuclei that will have the strongest impact in resolving some of the outstanding questions in nuclear astrophysics.

Particle collisions near a three-dimensional warped AdS black hole

NASA Astrophysics Data System (ADS)

Bécar, Ramón; González, P. A.; Vásquez, Yerko

2018-04-01

In this paper we consider the warped AdS3 black hole solution of topologically massive gravity with a negative cosmological constant, and we study the possibility that it acts as a particle accelerator by analyzing the energy in the center of mass (CM) frame of two colliding particles in the vicinity of its horizon, which is known as the Bañnados, Silk and West (BSW) process. Mainly, we show that the critical angular momentum (L_c) of the particle decreases when the warping parameter(ν ) increases. Also, we show that despite the particle with L_c being able to exist for certain values of the conserved energy outside the horizon, it will never reach the event horizon; therefore, the black hole cannot act as a particle accelerator with arbitrarily high CM energy on the event horizon. However, such a particle could also exist inside the outer horizon, with the BSW process being possible on the inner horizon. On the other hand, for the extremal warped AdS3 black hole, the particle with L_c and energy E could exist outside the event horizon and, the CM energy blows up on the event horizon if its conserved energy fulfills the condition E2>(ν 2+3)l2/3(ν ^{2-1)}, with the BSW process being possible.

Light-meson masses in an unquenched quark model

DOE PAGES

Chen, Xiaoyun; Ping, Jialun; Roberts, Craig D.; ...

2018-05-17

We perform a coupled-channels calculation of the masses of light mesons with the quantum numbers IJ P=-, (I,J) = 0,1, by includingmore » $$q\\bar{q}$$ and ($$q\\bar{q}$$) 2 components in a nonrelativistic chiral quark model. The coupling between two- and four-quark configurations is realized through a 3P 0 quark-pair creation model. With the usual form of this operator, the mass shifts are large and negative, an outcome which raises serious issues of validity for the quenched quark model. Therefore, we introduce some improvements of the 3P 0 operator in order to reduce the size of the mass shifts. By introducing two simple factors, physically well motivated, the coupling between $$q\\bar{q}$$ and ($$q\\bar{q}$$) 2 components is weakened, producing mass shifts that are around 10%–20% of hadron bare masses.« less

Light-meson masses in an unquenched quark model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Xiaoyun; Ping, Jialun; Roberts, Craig D.

We perform a coupled-channels calculation of the masses of light mesons with the quantum numbers IJ P=-, (I,J) = 0,1, by includingmore » $$q\\bar{q}$$ and ($$q\\bar{q}$$) 2 components in a nonrelativistic chiral quark model. The coupling between two- and four-quark configurations is realized through a 3P 0 quark-pair creation model. With the usual form of this operator, the mass shifts are large and negative, an outcome which raises serious issues of validity for the quenched quark model. Therefore, we introduce some improvements of the 3P 0 operator in order to reduce the size of the mass shifts. By introducing two simple factors, physically well motivated, the coupling between $$q\\bar{q}$$ and ($$q\\bar{q}$$) 2 components is weakened, producing mass shifts that are around 10%–20% of hadron bare masses.« less

Evaporation of large black holes in AdS: coupling to the evaporon

NASA Astrophysics Data System (ADS)

Rocha, Jorge V.

2008-08-01

Large black holes in an asymptotically AdS spacetime have a dual description in terms of approximately thermal states in the boundary CFT. The reflecting boundary conditions of AdS prevent such black holes from evaporating completely. On the other hand, the formulation of the information paradox becomes more stringent when a black hole is allowed to evaporate. In order to address the information loss problem from the AdS/CFT perspective we then need the boundary to become partially absorptive. We present a simple model that produces the necessary changes on the boundary by coupling a bulk scalar field to the evaporon, an external field propagating in one extra spatial dimension. The interaction is localized at the boundary of AdS and leads to partial transmission into the additional space. The transmission coefficient is computed in the planar limit and perturbatively in the coupling constant. Evaporation of the large black hole corresponds to cooling down the CFT by transferring energy to an external sector.

Consumption of added sugars from liquid but not solid sources predicts impaired glucose homeostasis and insulin resistance among youth at risk of obesity.

PubMed

Wang, Jiawei; Light, Kelly; Henderson, Mélanie; O'Loughlin, Jennifer; Mathieu, Marie-Eve; Paradis, Gilles; Gray-Donald, Katherine

2014-01-01

Little is known about longitudinal associations between added sugar consumption (solid and liquid sources) and glucose-insulin homeostasis among youth. Caucasian children (8-10 y) with at least one obese biological parent were recruited in the QUébec Adipose and Lifestyle InvesTigation in Youth (QUALITY) cohort (n = 630) and followed-up 2 y later (n = 564). Added sugars were assessed by 3 24-h dietary recalls at baseline. Two-year changes were examined in multivariate linear regression models, adjusting for baseline level, age, sex, Tanner stage, energy intake, fat mass (dual-energy X-ray absorptiometry), and physical activity (7 d accelerometer). Added sugar intake in either liquid or solid sources was not related to changes in adiposity measures (fat mass, body mass index, or waist circumference). However, a higher consumption (10 g/d) of added sugars from liquid sources was associated with 0.04 mmol/L higher fasting glucose, 2.3 pmol/L higher fasting insulin, 0.1 unit higher homeostasis model assessment of insulin resistance (HOMA-IR), and 0.4 unit lower Matsuda-insulin sensitivity index (Matsuda-ISI) in all participants (P < 0.01). No associations were observed with consumption of added sugars from solid sources. Overweight/obese children at baseline had greater increases in adiposity indicators, fasting insulin, and HOMA-IR and decreases in Matsuda-ISI during those 2 y than normal-weight children. Consumption of added sugars from liquid or solid sources was not associated with changes in adiposity, but liquid added sugars were a risk factor for the development of impaired glucose homeostasis and insulin resistance over 2 y among youth at risk of obesity.

Cross-national validation of prognostic models predicting sickness absence and the added value of work environment variables.

PubMed

Roelen, Corné A M; Stapelfeldt, Christina M; Heymans, Martijn W; van Rhenen, Willem; Labriola, Merete; Nielsen, Claus V; Bültmann, Ute; Jensen, Chris

2015-06-01

To validate Dutch prognostic models including age, self-rated health and prior sickness absence (SA) for ability to predict high SA in Danish eldercare. The added value of work environment variables to the models' risk discrimination was also investigated. 2,562 municipal eldercare workers (95% women) participated in the Working in Eldercare Survey. Predictor variables were measured by questionnaire at baseline in 2005. Prognostic models were validated for predictions of high (≥30) SA days and high (≥3) SA episodes retrieved from employer records during 1-year follow-up. The accuracy of predictions was assessed by calibration graphs and the ability of the models to discriminate between high- and low-risk workers was investigated by ROC-analysis. The added value of work environment variables was measured with Integrated Discrimination Improvement (IDI). 1,930 workers had complete data for analysis. The models underestimated the risk of high SA in eldercare workers and the SA episodes model had to be re-calibrated to the Danish data. Discrimination was practically useful for the re-calibrated SA episodes model, but not the SA days model. Physical workload improved the SA days model (IDI = 0.40; 95% CI 0.19-0.60) and psychosocial work factors, particularly the quality of leadership (IDI = 0.70; 95% CI 053-0.86) improved the SA episodes model. The prognostic model predicting high SA days showed poor performance even after physical workload was added. The prognostic model predicting high SA episodes could be used to identify high-risk workers, especially when psychosocial work factors are added as predictor variables.

AdViSHE: A Validation-Assessment Tool of Health-Economic Models for Decision Makers and Model Users.

PubMed

Vemer, P; Corro Ramos, I; van Voorn, G A K; Al, M J; Feenstra, T L

2016-04-01

A trade-off exists between building confidence in health-economic (HE) decision models and the use of scarce resources. We aimed to create a practical tool providing model users with a structured view into the validation status of HE decision models, to address this trade-off. A Delphi panel was organized, and was completed by a workshop during an international conference. The proposed tool was constructed iteratively based on comments from, and the discussion amongst, panellists. During the Delphi process, comments were solicited on the importance and feasibility of possible validation techniques for modellers, their relevance for decision makers, and the overall structure and formulation in the tool. The panel consisted of 47 experts in HE modelling and HE decision making from various professional and international backgrounds. In addition, 50 discussants actively engaged in the discussion at the conference workshop and returned 19 questionnaires with additional comments. The final version consists of 13 items covering all relevant aspects of HE decision models: the conceptual model, the input data, the implemented software program, and the model outcomes. Assessment of the Validation Status of Health-Economic decision models (AdViSHE) is a validation-assessment tool in which model developers report in a systematic way both on validation efforts performed and on their outcomes. Subsequently, model users can establish whether confidence in the model is justified or whether additional validation efforts should be undertaken. In this way, AdViSHE enhances transparency of the validation status of HE models and supports efficient model validation.

Immunotherapy of Alzheimer's disease (AD): from murine models to anti-amyloid beta (Abeta) human monoclonal antibodies.

PubMed

Geylis, Valeria; Steinitz, Michael

2006-01-01

The deposition of amyloid beta (Abeta) protein is a key pathological feature in Alzheimer's disease (AD). In murine models of AD, both active and passive immunization against Abeta induce a marked reduction in amyloid brain burden and an improvement in cognitive functions. Preliminary results of a prematurely terminated clinical trial where AD patients were actively vaccinated with aggregated Abeta bear resemblance to those documented in murine models. Passive immunization of AD patients with anti-Abeta antibodies, in particular human antibodies, is a strategy that provides a more cautious management and control of any undesired side effects. Sera of all healthy adults contain anti-Abeta IgG autoimmune antibodies. Hence antigen-committed human B-cells are easily immortalized by Epstein-Barr virus (EBV) into anti-Abeta secreting cell lines. Two anti-Abeta human monoclonal antibodies which we recently prepared bind to the N-terminus of Abeta peptide and were shown to stain amyloid plaques in non-fixed brain sections from an AD patient. It is anticipated that specifically selected anti-Abeta human monoclonal antibodies could reduce and inhibit deposits of amyloid in brain while avoiding the cognitive decline that characterizes AD. In the future, this type of antibody may prove to be a promising immune therapy for the disease.

Vacuum currents in braneworlds on AdS bulk with compact dimensions

NASA Astrophysics Data System (ADS)

Bellucci, S.; Saharian, A. A.; Vardanyan, V.

2015-11-01

The two-point function and the vacuum expectation value (VEV) of the current density are investigated for a massive charged scalar field with arbitrary curvature coupling in the geometry of a brane on the background of AdS spacetime with partial toroidal compactification. The presence of a gauge field flux, enclosed by compact dimensions, is assumed. On the brane the field obeys Robin boundary condition and along compact dimensions periodicity conditions with general phases are imposed. There is a range in the space of the values for the coefficient in the boundary condition where the Poincaré vacuum is unstable. This range depends on the location of the brane and is different for the regions between the brane and AdS boundary and between the brane and the horizon. In models with compact dimensions the stability condition is less restrictive than that for the AdS bulk with trivial topology. The vacuum charge density and the components of the current along non-compact dimensions vanish. The VEV of the current density along compact dimensions is a periodic function of the gauge field flux with the period equal to the flux quantum. It is decomposed into the boundary-free and brane-induced contributions. The asymptotic behavior of the latter is investigated near the brane, near the AdS boundary and near the horizon. It is shown that, in contrast to the VEVs of the field squared an denergy-momentum tensor, the current density is finite on the brane and vanishes for the special case of Dirichlet boundary condition. Both the boundary-free and brane-induced contributions vanish on the AdS boundary. The brane-induced contribution vanishes on the horizon and for points near the horizon the current is dominated by the boundary-free part. In the near-horizon limit, the latter is connected to the corresponding quantity for a massless field in the Minkowski bulk by a simple conformal relation. Depending on the value of the Robin coefficient, the presence of the brane can either

A model-free method for mass spectrometer response correction. [for oxygen consumption and cardiac output calculation

NASA Technical Reports Server (NTRS)

Shykoff, Barbara E.; Swanson, Harvey T.

1987-01-01

A new method for correction of mass spectrometer output signals is described. Response-time distortion is reduced independently of any model of mass spectrometer behavior. The delay of the system is found first from the cross-correlation function of a step change and its response. A two-sided time-domain digital correction filter (deconvolution filter) is generated next from the same step response data using a regression procedure. Other data are corrected using the filter and delay. The mean squared error between a step response and a step is reduced considerably more after the use of a deconvolution filter than after the application of a second-order model correction. O2 consumption and CO2 production values calculated from data corrupted by a simulated dynamic process return to near the uncorrupted values after correction. Although a clean step response or the ensemble average of several responses contaminated with noise is needed for the generation of the filter, random noise of magnitude not above 0.5 percent added to the response to be corrected does not impair the correction severely.

The Effective Mass of a Ball in the Air

ERIC Educational Resources Information Center

Messer, J.; Pantaleone, J.

2010-01-01

The air surrounding a projectile affects the projectile's motion in three very different ways: the drag force, the buoyant force, and the added mass. The added mass is an increase in the projectile's inertia from the motion of the air around it. Here we experimentally measure the added mass of a spherical projectile in air. The results agree well…

The effect of adjusting model inputs to achieve mass balance on time-dynamic simulations in a food-web model of Lake Huron

USGS Publications Warehouse

Langseth, Brian J.; Jones, Michael L.; Riley, Stephen C.

2014-01-01

Ecopath with Ecosim (EwE) is a widely used modeling tool in fishery research and management. Ecopath requires a mass-balanced snapshot of a food web at a particular point in time, which Ecosim then uses to simulate changes in biomass over time. Initial inputs to Ecopath, including estimates for biomasses, production to biomass ratios, consumption to biomass ratios, and diets, rarely produce mass balance, and thus ad hoc changes to inputs are required to balance the model. There has been little previous research of whether ad hoc changes to achieve mass balance affect Ecosim simulations. We constructed an EwE model for the offshore community of Lake Huron, and balanced the model using four contrasting but realistic methods. The four balancing methods were based on two contrasting approaches; in the first approach, production of unbalanced groups was increased by increasing either biomass or the production to biomass ratio, while in the second approach, consumption of predators on unbalanced groups was decreased by decreasing either biomass or the consumption to biomass ratio. We compared six simulation scenarios based on three alternative assumptions about the extent to which mortality rates of prey can change in response to changes in predator biomass (i.e., vulnerabilities) under perturbations to either fishing mortality or environmental production. Changes in simulated biomass values over time were used in a principal components analysis to assess the comparative effect of balancing method, vulnerabilities, and perturbation types. Vulnerabilities explained the most variation in biomass, followed by the type of perturbation. Choice of balancing method explained little of the overall variation in biomass. Under scenarios where changes in predator biomass caused large changes in mortality rates of prey (i.e., high vulnerabilities), variation in biomass was greater than when changes in predator biomass caused only small changes in mortality rates of prey (i.e., low

Constructing the AdS dual of a Fermi liquid: AdS black holes with Dirac hair

NASA Astrophysics Data System (ADS)

Čubrović, Mihailo; Zaanen, Jan; Schalm, Koenraad

2011-10-01

We provide evidence that the holographic dual to a strongly coupled charged Fermi liquid has a non-zero fermion density in the bulk. We show that the pole-strength of the stable quasiparticle characterizing the Fermi surface is encoded in the AdS probability density of a single normalizable fermion wavefunction in AdS. Recalling Migdal's theorem which relates the pole strength to the Fermi-Dirac characteristic discontinuity in the number density at ω F , we conclude that the AdS dual of a Fermi liquid is described by occupied on-shell fermionic modes in AdS. Encoding the occupied levels in the total spatially averaged probability density of the fermion field directly, we show that an AdS Reissner-Nordström black holein a theory with charged fermions has a critical temperature, at which the system undergoes a first-order transition to a black hole with a non-vanishing profile for the bulk fermion field. Thermodynamics and spectral analysis support that the solution with non-zero AdS fermion-profile is the preferred ground state at low temperatures.

Value Added in English Schools

ERIC Educational Resources Information Center

Ray, Andrew; McCormack, Tanya; Evans, Helen

2009-01-01

Value-added indicators are now a central part of school accountability in England, and value-added information is routinely used in school improvement at both the national and the local levels. This article describes the value-added models that are being used in the academic year 2007-8 by schools, parents, school inspectors, and other…

Segmented strings in AdS 3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Callebaut, Nele; Gubser, Steven S.; Samberg, Andreas

We study segmented strings in flat space and in AdS 3. In flat space, these well known classical motions describe strings which at any instant of time are piecewise linear. In AdS 3, the worldsheet is composed of faces each of which is a region bounded by null geodesics in an AdS 2 subspace of AdS 3. The time evolution can be described by specifying the null geodesic motion of kinks in the string at which two segments are joined. The outcome of collisions of kinks on the worldsheet can be worked out essentially using considerations of causality. We studymore » several examples of closed segmented strings in AdS 3 and find an unexpected quasi-periodic behavior. Here, we also work out a WKB analysis of quantum states of yo-yo strings in AdS 5 and find a logarithmic term reminiscent of the logarithmic twist of string states on the leading Regge trajectory.« less

Segmented strings in AdS 3

DOE PAGES

Callebaut, Nele; Gubser, Steven S.; Samberg, Andreas; ...

2015-11-17

We study segmented strings in flat space and in AdS 3. In flat space, these well known classical motions describe strings which at any instant of time are piecewise linear. In AdS 3, the worldsheet is composed of faces each of which is a region bounded by null geodesics in an AdS 2 subspace of AdS 3. The time evolution can be described by specifying the null geodesic motion of kinks in the string at which two segments are joined. The outcome of collisions of kinks on the worldsheet can be worked out essentially using considerations of causality. We studymore » several examples of closed segmented strings in AdS 3 and find an unexpected quasi-periodic behavior. Here, we also work out a WKB analysis of quantum states of yo-yo strings in AdS 5 and find a logarithmic term reminiscent of the logarithmic twist of string states on the leading Regge trajectory.« less

School system evaluation by value added analysis under endogeneity.

PubMed

Manzi, Jorge; San Martín, Ernesto; Van Bellegem, Sébastien

2014-01-01

Value added is a common tool in educational research on effectiveness. It is often modeled as a (prediction of a) random effect in a specific hierarchical linear model. This paper shows that this modeling strategy is not valid when endogeneity is present. Endogeneity stems, for instance, from a correlation between the random effect in the hierarchical model and some of its covariates. This paper shows that this phenomenon is far from exceptional and can even be a generic problem when the covariates contain the prior score attainments, a typical situation in value added modeling. Starting from a general, model-free definition of value added, the paper derives an explicit expression of the value added in an endogeneous hierarchical linear Gaussian model. Inference on value added is proposed using an instrumental variable approach. The impact of endogeneity on the value added and the estimated value added is calculated accurately. This is also illustrated on a large data set of individual scores of about 200,000 students in Chile.

ACCURATE LOW-MASS STELLAR MODELS OF KOI-126

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feiden, Gregory A.; Chaboyer, Brian; Dotter, Aaron, E-mail: gregory.a.feiden@dartmouth.edu

2011-10-10

The recent discovery of an eclipsing hierarchical triple system with two low-mass stars in a close orbit (KOI-126) by Carter et al. appeared to reinforce the evidence that theoretical stellar evolution models are not able to reproduce the observational mass-radius relation for low-mass stars. We present a set of stellar models for the three stars in the KOI-126 system that show excellent agreement with the observed radii. This agreement appears to be due to the equation of state implemented by our code. A significant dispersion in the observed mass-radius relation for fully convective stars is demonstrated; indicative of the influencemore » of physics currently not incorporated in standard stellar evolution models. We also predict apsidal motion constants for the two M dwarf companions. These values should be observationally determined to within 1% by the end of the Kepler mission.« less

AdS and stabilized extra dimensions in multi-dimensional gravitational models with nonlinear scalar curvature terms R-1 and R4

NASA Astrophysics Data System (ADS)

Günther, Uwe; Zhuk, Alexander; Bezerra, Valdir B.; Romero, Carlos

2005-08-01

We study multi-dimensional gravitational models with scalar curvature nonlinearities of types R-1 and R4. It is assumed that the corresponding higher dimensional spacetime manifolds undergo a spontaneous compactification to manifolds with a warped product structure. Special attention has been paid to the stability of the extra-dimensional factor spaces. It is shown that for certain parameter regions the systems allow for a freezing stabilization of these spaces. In particular, we find for the R-1 model that configurations with stabilized extra dimensions do not provide a late-time acceleration (they are AdS), whereas the solution branch which allows for accelerated expansion (the dS branch) is incompatible with stabilized factor spaces. In the case of the R4 model, we obtain that the stability region in parameter space depends on the total dimension D = dim(M) of the higher dimensional spacetime M. For D > 8 the stability region consists of a single (absolutely stable) sector which is shielded from a conformal singularity (and an antigravity sector beyond it) by a potential barrier of infinite height and width. This sector is smoothly connected with the stability region of a curvature-linear model. For D < 8 an additional (metastable) sector exists which is separated from the conformal singularity by a potential barrier of finite height and width so that systems in this sector are prone to collapse into the conformal singularity. This second sector is not smoothly connected with the first (absolutely stable) one. Several limiting cases and the possibility of inflation are discussed for the R4 model.

Gravitational leptogenesis, reheating, and models of neutrino mass

NASA Astrophysics Data System (ADS)

Adshead, Peter; Long, Andrew J.; Sfakianakis, Evangelos I.

2018-02-01

Gravitational leptogenesis refers to a class of baryogenesis models in which the matter-antimatter asymmetry of the Universe arises through the standard model lepton-number gravitational anomaly. In these models chiral gravitational waves source a lepton asymmetry in standard model neutrinos during the inflationary epoch. We point out that gravitational leptogenesis can be successful in either the Dirac or Majorana neutrino mass scenario. In the Dirac mass scenario, gravitational leptogenesis predicts a relic abundance of sterile neutrinos that remain out of equilibrium, and the lepton asymmetry carried by the standard model sector is unchanged. In the Majorana mass scenario, the neutrinos participate in lepton-number-violating interactions that threaten to wash out the lepton asymmetry during postinflationary reheating. However, we show that a complete (exponential) washout of the lepton asymmetry is prevented if the lepton-number-violating interactions go out of equilibrium before all of the standard model Yukawa interactions come into equilibrium. The baryon and lepton asymmetries carried by right-chiral quarks and leptons are sequestered from the lepton-number violation, and the washout processes only suppress the predicted baryon asymmetry by a factor of ɛw .o .=±O (0.1 ). The sign of ɛw .o . depends on the model parameters in such a way that a future measurement of the primordial gravitational wave chirality would constrain the scale of lepton-number violation (heavy Majorana neutrino mass).

Evolution, Nucleosynthesis, and Yields of AGB Stars at Different Metallicities. III. Intermediate-mass Models, Revised Low-mass Models, and the ph-FRUITY Interface

NASA Astrophysics Data System (ADS)

Cristallo, S.; Straniero, O.; Piersanti, L.; Gobrecht, D.

2015-08-01

We present a new set of models for intermediate-mass asymptotic giant branch (AGB) stars (4.0, 5.0, and 6.0 M⊙) at different metallicities (-2.15 ≤ [Fe/H] ≤ +0.15). This set integrates the existing models for low-mass AGB stars (1.3 ≤ M/M⊙ ≤ 3.0) already included in the FRUITY database. We describe the physical and chemical evolution of the computed models from the main sequence up to the end of the AGB phase. Due to less efficient third dredge up episodes, models with large core masses show modest surface enhancements. This effect is due to the fact that the interpulse phases are short and, therefore, thermal pulses (TPs) are weak. Moreover, the high temperature at the base of the convective envelope prevents it from deeply penetrating the underlying radiative layers. Depending on the initial stellar mass, the heavy element nucleosynthesis is dominated by different neutron sources. In particular, the s-process distributions of the more massive models are dominated by the 22Ne(α,n)25Mg reaction, which is efficiently activated during TPs. At low metallicities, our models undergo hot bottom burning and hot third dredge up. We compare our theoretical final core masses to available white dwarf observations. Moreover, we quantify the influence intermediate-mass models have on the carbon star luminosity function. Finally, we present the upgrade of the FRUITY web interface, which now also includes the physical quantities of the TP-AGB phase for all of the models included in the database (ph-FRUITY).

Added sugars and periodontal disease in young adults: an analysis of NHANES III data.

PubMed

Lula, Estevam C O; Ribeiro, Cecilia C C; Hugo, Fernando N; Alves, Cláudia M C; Silva, Antônio A M

2014-10-01

Added sugar consumption seems to trigger a hyperinflammatory state and may result in visceral adiposity, dyslipidemia, and insulin resistance. These conditions are risk factors for periodontal disease. However, the role of sugar intake in the cause of periodontal disease has not been adequately studied. We evaluated the association between the frequency of added sugar consumption and periodontal disease in young adults by using NHANES III data. Data from 2437 young adults (aged 18-25 y) who participated in NHANES III (1988-1994) were analyzed. We estimated the frequency of added sugar consumption by using food-frequency questionnaire responses. We considered periodontal disease to be present in teeth with bleeding on probing and a probing depth ≥3 mm at one or more sites. We evaluated this outcome as a discrete variable in Poisson regression models and as a categorical variable in multinomial logistic regression models adjusted for sex, age, race-ethnicity, education, poverty-income ratio, tobacco exposure, previous diagnosis of diabetes, and body mass index. A high consumption of added sugars was associated with a greater prevalence of periodontal disease in middle [prevalence ratio (PR): 1.39; 95% CI: 1.02, 1.89] and upper (PR: 1.42; 95% CI: 1.08, 1.85) tertiles of consumption in the adjusted Poisson regression model. The upper tertile of added sugar intake was associated with periodontal disease in ≥2 teeth (PR: 1.73; 95% CI: 1.19, 2.52) but not with periodontal disease in only one tooth (PR: 0.85; 95% CI: 0.54, 1.34) in the adjusted multinomial logistic regression model. A high frequency of consumption of added sugars is associated with periodontal disease, independent of traditional risk factors, suggesting that this consumption pattern may contribute to the systemic inflammation observed in periodontal disease and associated noncommunicable diseases. © 2014 American Society for Nutrition.

Anxiety-like behavior as an early endophenotype in the TgF344-AD rat model of Alzheimer's disease.

PubMed

Pentkowski, Nathan S; Berkowitz, Laura E; Thompson, Shannon M; Drake, Emma N; Olguin, Carlos R; Clark, Benjamin J

2018-01-01

Alzheimer's disease (AD) is characterized by progressive cognitive decline and the presence of aggregates of amyloid beta (plaques) and hyperphosphorylated tau (tangles). Early diagnosis through neuropsychological testing is difficult due to comorbidity of symptoms between AD and other types of dementia. As a result, there is a need to identify the range of behavioral phenotypes expressed in AD. In the present study, we utilized a transgenic rat (TgF344-AD) model that bears the mutated amyloid precursor protein as well as presenilin-1 genes, resulting in progressive plaque and tangle pathogenesis throughout the cortex. We tested young adult male and female TgF344-AD rats in a spatial memory task in the Morris water maze and for anxiety-like behavior in the elevated plus-maze. Results indicated that regardless of sex, TgF344-AD rats exhibited increased anxiety-like behavior in the elevated plus-maze, which occurred without significant deficits in the spatial memory. Together, these results indicate that enhanced anxiety-like behavior represents an early-stage behavioral marker in the TgF344-AD rat model. Copyright © 2017 Elsevier Inc. All rights reserved.

A Correlated Random Effects Model for Nonignorable Missing Data in Value-Added Assessment of Teacher Effects

ERIC Educational Resources Information Center

Karl, Andrew T.; Yang, Yan; Lohr, Sharon L.

2013-01-01

Value-added models have been widely used to assess the contributions of individual teachers and schools to students' academic growth based on longitudinal student achievement outcomes. There is concern, however, that ignoring the presence of missing values, which are common in longitudinal studies, can bias teachers' value-added scores.…

Bayesian modeling of the mass and density of asteroids

NASA Astrophysics Data System (ADS)

Dotson, Jessie L.; Mathias, Donovan

2017-10-01

Mass and density are two of the fundamental properties of any object. In the case of near earth asteroids, knowledge about the mass of an asteroid is essential for estimating the risk due to (potential) impact and planning possible mitigation options. The density of an asteroid can illuminate the structure of the asteroid. A low density can be indicative of a rubble pile structure whereas a higher density can imply a monolith and/or higher metal content. The damage resulting from an impact of an asteroid with Earth depends on its interior structure in addition to its total mass, and as a result, density is a key parameter to understanding the risk of asteroid impact. Unfortunately, measuring the mass and density of asteroids is challenging and often results in measurements with large uncertainties. In the absence of mass / density measurements for a specific object, understanding the range and distribution of likely values can facilitate probabilistic assessments of structure and impact risk. Hierarchical Bayesian models have recently been developed to investigate the mass - radius relationship of exoplanets (Wolfgang, Rogers & Ford 2016) and to probabilistically forecast the mass of bodies large enough to establish hydrostatic equilibrium over a range of 9 orders of magnitude in mass (from planemos to main sequence stars; Chen & Kipping 2017). Here, we extend this approach to investigate the mass and densities of asteroids. Several candidate Bayesian models are presented, and their performance is assessed relative to a synthetic asteroid population. In addition, a preliminary Bayesian model for probablistically forecasting masses and densities of asteroids is presented. The forecasting model is conditioned on existing asteroid data and includes observational errors, hyper-parameter uncertainties and intrinsic scatter.

An improved nuclear mass model: FRDM (2012)

NASA Astrophysics Data System (ADS)

Moller, Peter

2011-10-01

We have developed an improved nuclear mass model which we plan to finalize in 2012, so we designate it FRDM(2012). Relative to our previous mass table in 1995 we do a full four-dimensional variation of the shape coordinates EPS2, EPS3, EPS4, and EPS6, we consider axial asymmetric shape degrees of freedom and we vary the density symmetry parameter L. Other additional features are also implemented. With respect to the Audi 2003 data base we now have an accuracy of 0.57 MeV. We have carefully tested the extrapolation properties of the new mass table by adjusting model parameters to limited data sets and testing on extended data sets and find it is highly reliable in new regions of nuclei. We discuss what the remaining differences between model calculations and experiment tell us about the limitations of the currently used effective single-particle potential and possible extensions. DOE No. DE-AC52-06NA25396.

Neutrino masses in the Lee-Wick standard model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Espinosa, Jose Ramon; Grinstein, Benjamin; O'Connell, Donal

2008-04-15

Recently, an extension of the standard model based on ideas of Lee and Wick has been discussed. This theory is free of quadratic divergences and hence has a Higgs mass that is stable against radiative corrections. Here, we address the question of whether or not it is possible to couple very heavy particles, with masses much greater than the weak scale, to the Lee-Wick standard model degrees of freedom and still preserve the stability of the weak scale. We show that in the LW-standard model the familiar seesaw mechanism for generating neutrino masses preserves the solution to the hierarchy puzzlemore » provided by the higher derivative terms. The very heavy right-handed neutrinos do not destabilize the Higgs mass. We give an example of new heavy degrees of freedom that would destabilize the hierarchy, and discuss a general mechanism for coupling other heavy degrees of freedom to the Higgs doublet while preserving the hierarchy.« less

A mass diffusion-based interpretation of the effect of total solids content on solid-state anaerobic digestion of cellulosic biomass.

PubMed

Xu, Fuqing; Wang, Zhi-Wu; Tang, Li; Li, Yebo

2014-09-01

In solid-state anaerobic digestion (SS-AD) of cellulosic biomass, the volumetric methane production rate has often been found to increase with the increase in total solids (TS) content until a threshold is reached, and then to decrease. This phenomenon cannot be explained by conventional understanding derived from liquid anaerobic digestion. This study proposed that the high TS content-caused mass diffusion limitation may be responsible for the observed methane production deterioration. Based on this hypothesis, a new SS-AD model was developed by taking into account the mass diffusion limitation and hydrolysis inhibition. The good agreement between model simulation and the experimental as well as literature data verified that the observed reduction in volumetric methane production rate could be ascribed to hydrolysis inhibition as a result of the mass diffusion limitation in SS-AD. Copyright © 2014 Elsevier Ltd. All rights reserved.

Intratumoral delivery of docetaxel enhances antitumor activity of Ad-p53 in murine head and neck cancer xenograft model.

PubMed

Yoo, George H; Subramanian, Geetha; Ezzat, Waleed H; Tulunay, Ozlem E; Tran, Vivian R; Lonardo, Fulvio; Ensley, John F; Kim, Harold; Won, Joshua; Stevens, Timothy; Zumstein, Louis A; Lin, Ho-Sheng

2010-01-01

The aim of this study is to determine the ability of intratumorally delivered docetaxel to enhance the antitumor activity of adenovirus-mediated delivery of p53 (Ad-p53) in murine head and neck cancer xenograft model. A xenograft head and neck squamous cell carcinoma mouse model was used. Mice were randomized into 4 groups of 6 mice receiving 6 weeks of biweekly intratumoral injection of (a) diluent, (b) Ad-p53 (1 x 10(10) viral particles per injection), (c) docetaxel (1 mg/kg per injection), and (d) combination of Ad-p53 (1 x 10(10) viral particles per injection) and docetaxel (1 mg/kg per injection). Tumor size, weight, toxicity, and overall and disease-free survival rates were determined. Intratumoral treatments with either docetaxel alone or Ad-p53 alone resulted in statistically significant antitumor activity and improved survival compared with control group. Furthermore, combined delivery of Ad-p53 and docetaxel resulted in a statistically significant reduction in tumor weight when compared to treatment with either Ad-p53 or docetaxel alone. Intratumoral delivery of docetaxel enhanced the antitumor effect of Ad-p53 in murine head and neck cancer xenograft model. The result of this preclinical in vivo study is promising and supports further clinical testing to evaluate efficacy of combined intratumoral docetaxel and Ad-p53 in treatment of head and neck cancer. Copyright (c) 2010 Elsevier Inc. All rights reserved.

Sensitivity of Value Added School Effect Estimates to Different Model Specifications and Outcome Measures

ERIC Educational Resources Information Center

Pride, Bryce L.

2012-01-01

The Adequate Yearly Progress (AYP) Model has been used to make many high-stakes decisions concerning schools, though it does not provide a complete assessment of student academic achievement and school effectiveness. To provide a clearer perspective, many states have implemented various Growth and Value Added Models, in addition to AYP. The…

SOA-based model for value-added ITS services delivery.

PubMed

Herrera-Quintero, Luis Felipe; Maciá-Pérez, Francisco; Marcos-Jorquera, Diego; Gilart-Iglesias, Virgilio

2014-01-01

Integration is currently a key factor in intelligent transportation systems (ITS), especially because of the ever increasing service demands originating from the ITS industry and ITS users. The current ITS landscape is made up of multiple technologies that are tightly coupled, and its interoperability is extremely low, which limits ITS services generation. Given this fact, novel information technologies (IT) based on the service-oriented architecture (SOA) paradigm have begun to introduce new ways to address this problem. The SOA paradigm allows the construction of loosely coupled distributed systems that can help to integrate the heterogeneous systems that are part of ITS. In this paper, we focus on developing an SOA-based model for integrating information technologies (IT) into ITS to achieve ITS service delivery. To develop our model, the ITS technologies and services involved were identified, catalogued, and decoupled. In doing so, we applied our SOA-based model to integrate all of the ITS technologies and services, ranging from the lowest-level technical components, such as roadside unit as a service (RSUAAS), to the most abstract ITS services that will be offered to ITS users (value-added services). To validate our model, a functionality case study that included all of the components of our model was designed.

Assessing the TARES as an ethical model for antismoking ads.

PubMed

Lee, Seow Ting; Cheng, I-Huei

2010-01-01

This study examines the ethical dimensions of public health communication, with a focus on antismoking public service announcements (PSAs). The content analysis of 826 television ads from the U.S. Centers for Disease Control and Prevention's (CDC) Media Campaign Resource Center is an empirical testing of Baker and Martinson's (2001) TARES Test that directly examines persuasive messages for truthfulness, authenticity, respect, equity, and social responsibility. In general, the antismoking ads score highly on ethicality. There are significant relationships between ethicality and message attributes (thematic frame, emotion appeal, source, and target audience). Ads that portrayed smoking as damaging to health and socially unacceptable score lower in ethicality than ads that focus on tobacco industry manipulation, addiction, dangers of secondhand smoke, and cessation. Emotion appeals of anger and sadness are associated with higher ethicality than shame and humor appeals. Ads targeting teen/youth audiences score lower on ethicality than ads targeting adult and general audiences. There are significant differences in ethicality based on source; ads produced by the CDC rate higher in ethicality than other sources. Theoretical implications and practical recommendations are discussed.

(2 + 1)-dimensional interacting model of two massless spin-2 fields as a bi-gravity model

NASA Astrophysics Data System (ADS)

Hoseinzadeh, S.; Rezaei-Aghdam, A.

2018-06-01

We propose a new group-theoretical (Chern-Simons) formulation for the bi-metric theory of gravity in (2 + 1)-dimensional spacetime which describe two interacting massless spin-2 fields. Our model has been formulated in terms of two dreibeins rather than two metrics. We obtain our Chern-Simons gravity model by gauging mixed AdS-AdS Lie algebra and show that it has a two dimensional conformal field theory (CFT) at the boundary of the anti de Sitter (AdS) solution. We show that the central charge of the dual CFT is proportional to the mass of the AdS solution. We also study cosmological implications of our massless bi-gravity model.

Assessing the effect of adding interactive modeling to the geoscience curriculum

NASA Astrophysics Data System (ADS)

Castillo, A.; Marshall, J.; Cardenas, M.

2013-12-01

Technology and computer models enhance the learning experience when appropriately utilized. Moreover, learning is significantly improved when effective visualization is combined with models of processes allowing for inquiry-based problem solving. Still, hands-on experiences in real scenarios result in better contextualization of related problems compared to virtual laboratories. Therefore, the role of scientific visualization, technology, and computer modeling is to enhance, not displace, the learning experience by supplementing real-world problem solving and experiences, although in some circumstances, they can adequately serve to take the place of reality. The key to improving scientific education is to embrace an inquiry-based approach that favorably uses technology. This study will attempt to evaluate the effect of adding interactive modeling to the geological sciences curriculum. An assessment tool, designed to assess student understanding of physical hydrology, was used to evaluate a curriculum intervention based on student learning with a data- and modeling-driven approach using COMSOL Multiphysics software. This intervention was implemented in an upper division and graduate physical hydrology course in fall 2012. Students enrolled in the course in fall 2011 served as the control group. Interactive modeling was added to the curriculum in fall 2012 to replace the analogous mathematical modeling done by hand in fall 2011. Pre- and post-test results were used to assess and report its effectiveness. Student interviews were also used to probe student reactions to both the experimental and control curricula. The pre- and post-tests asked students to describe the significant processes in the hydrological cycle and describe the laws governing these processes. Their ability to apply their knowledge in a real-world problem was also assessed. Since the pre- and post-test data failed to meet the assumption of normality, a non-parametric Kruskal-Wallis test was run to

Analytical Models of Cross-Layer Protocol Optimization in Real-Time Wireless Sensor Ad Hoc Networks

NASA Astrophysics Data System (ADS)

Hortos, William S.

The real-time interactions among the nodes of a wireless sensor network (WSN) to cooperatively process data from multiple sensors are modeled. Quality-of-service (QoS) metrics are associated with the quality of fused information: throughput, delay, packet error rate, etc. Multivariate point process (MVPP) models of discrete random events in WSNs establish stochastic characteristics of optimal cross-layer protocols. Discrete-event, cross-layer interactions in mobile ad hoc network (MANET) protocols have been modeled using a set of concatenated design parameters and associated resource levels by the MVPPs. Characterization of the "best" cross-layer designs for a MANET is formulated by applying the general theory of martingale representations to controlled MVPPs. Performance is described in terms of concatenated protocol parameters and controlled through conditional rates of the MVPPs. Modeling limitations to determination of closed-form solutions versus explicit iterative solutions for ad hoc WSN controls are examined.

A Reanalysis of the Effects of Teacher Replacement Using Value-Added Modeling

ERIC Educational Resources Information Center

Yeh, Stuart S.

2013-01-01

Background: In principle, value-added modeling (VAM) might be justified if it can be shown to be a more reliable indicator of teacher quality than existing indicators for existing low-stakes decisions that are already being made, such as the award of small merit bonuses. However, a growing number of researchers now advocate the use of VAM to…

Methods for Accounting for Co-Teaching in Value-Added Models. Working Paper

ERIC Educational Resources Information Center

Hock, Heinrich; Isenberg, Eric

2012-01-01

Isolating the effect of a given teacher on student achievement (value-added modeling) is complicated when the student is taught the same subject by more than one teacher. We consider three methods, which we call the Partial Credit Method, Teacher Team Method, and Full Roster Method, for estimating teacher effects in the presence of co-teaching.…

In silico strain optimization by adding reactions to metabolic models.

PubMed

Correia, Sara; Rocha, Miguel

2012-07-24

Nowadays, the concerns about the environment and the needs to increase the productivity at low costs, demand for the search of new ways to produce compounds with industrial interest. Based on the increasing knowledge of biological processes, through genome sequencing projects, and high-throughput experimental techniques as well as the available computational tools, the use of microorganisms has been considered as an approach to produce desirable compounds. However, this usually requires to manipulate these organisms by genetic engineering and/ or changing the enviromental conditions to make the production of these compounds possible. In many cases, it is necessary to enrich the genetic material of those microbes with hereologous pathways from other species and consequently adding the potential to produce novel compounds. This paper introduces a new plug-in for the OptFlux Metabolic Engineering platform, aimed at finding suitable sets of reactions to add to the genomes of selected microbes (wild type strain), as well as finding complementary sets of deletions, so that the mutant becomes able to overproduce compounds with industrial interest, while preserving their viability. The necessity of adding reactions to the metabolic model arises from existing gaps in the original model or motivated by the productions of new compounds by the organism. The optimization methods used are metaheuristics such as Evolutionary Algorithms and Simulated Annealing. The usefulness of this plug-in is demonstrated by a case study, regarding the production of vanillin by the bacterium E. coli.

In silico strain optimization by adding reactions to metabolic models.

PubMed

Correia, Sara; Rocha, Miguel

2012-12-01

Nowadays, the concerns about the environment and the needs to increase the productivity at low costs, demand for the search of new ways to produce compounds with industrial interest. Based on the increasing knowledge of biological processes, through genome sequencing projects, and high-throughput experimental techniques as well as the available computational tools, the use of microorganisms has been considered as an approach to produce desirable compounds. However, this usually requires to manipulate these organisms by genetic engineering and/ or changing the enviromental conditions to make the production of these compounds possible. In many cases, it is necessary to enrich the genetic material of those microbes with hereologous pathways from other species and consequently adding the potential to produce novel compounds. This paper introduces a new plug-in for the OptFlux Metabolic Engineering platform, aimed at finding suitable sets of reactions to add to the genomes of selected microbes (wild type strain), as well as finding complementary sets of deletions, so that the mutant becomes able to overproduce compounds with industrial interest, while preserving their viability. The necessity of adding reactions to the metabolic model arises from existing gaps in the original model or motivated by the productions of new compounds by the organism. The optimization methods used are metaheuristics such as Evolutionary Algorithms and Simulated Annealing. The usefulness of this plug-in is demonstrated by a case study, regarding the production of vanillin by the bacterium E. coli.

Modeling and Simulation of Variable Mass, Flexible Structures

NASA Technical Reports Server (NTRS)

Tobbe, Patrick A.; Matras, Alex L.; Wilson, Heath E.

2009-01-01

The advent of the new Ares I launch vehicle has highlighted the need for advanced dynamic analysis tools for variable mass, flexible structures. This system is composed of interconnected flexible stages or components undergoing rapid mass depletion through the consumption of solid or liquid propellant. In addition to large rigid body configuration changes, the system simultaneously experiences elastic deformations. In most applications, the elastic deformations are compatible with linear strain-displacement relationships and are typically modeled using the assumed modes technique. The deformation of the system is approximated through the linear combination of the products of spatial shape functions and generalized time coordinates. Spatial shape functions are traditionally composed of normal mode shapes of the system or even constraint modes and static deformations derived from finite element models of the system. Equations of motion for systems undergoing coupled large rigid body motion and elastic deformation have previously been derived through a number of techniques [1]. However, in these derivations, the mode shapes or spatial shape functions of the system components were considered constant. But with the Ares I vehicle, the structural characteristics of the system are changing with the mass of the system. Previous approaches to solving this problem involve periodic updates to the spatial shape functions or interpolation between shape functions based on system mass or elapsed mission time. These solutions often introduce misleading or even unstable numerical transients into the system. Plus, interpolation on a shape function is not intuitive. This paper presents an approach in which the shape functions are held constant and operate on the changing mass and stiffness matrices of the vehicle components. Each vehicle stage or component finite element model is broken into dry structure and propellant models. A library of propellant models is used to describe the

HOW GAS-DYNAMIC FLARE MODELS POWERED BY PETSCHEK RECONNECTION DIFFER FROM THOSE WITH AD HOC ENERGY SOURCES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Longcope, D. W.; Klimchuk, J. A.

Aspects of solar flare dynamics, such as chromospheric evaporation and flare light curves, have long been studied using one-dimensional models of plasma dynamics inside a static flare loop, subjected to some energy input. While extremely successful at explaining the observed characteristics of flares, all such models so far have specified energy input ad hoc, rather than deriving it self-consistently. There is broad consensus that flares are powered by magnetic energy released through reconnection. Recent work has generalized Petschek’s basic reconnection scenario, topological change followed by field line retraction and shock heating, to permit its inclusion in a one-dimensional flare loop model. Heremore » we compare the gas dynamics driven by retraction and shocking to those from more conventional static loop models energized by ad hoc source terms. We find significant differences during the first minute, when retraction leads to larger kinetic energies and produces higher densities at the loop top, while ad hoc heating tends to rarify the loop top. The loop-top density concentration is related to the slow magnetosonic shock, characteristic of Petschek’s model, but persists beyond the retraction phase occurring in the outflow jet. This offers an explanation for observed loop-top sources of X-ray and EUV emission, with advantages over that provided by ad hoc heating scenarios. The cooling phases of the two models are, however, notably similar to one another, suggesting that observations at that stage will yield little information on the nature of energy input.« less

Fast spinning strings on η deformed AdS 5 × S 5

NASA Astrophysics Data System (ADS)

Banerjee, Aritra; Bhattacharyya, Arpan; Roychowdhury, Dibakar

2018-02-01

In this paper, considering the correspondence between spin chains and string sigma models, we explore the rotating string solutions over η deformed AdS 5 × S 5 in the so-called fast spinning limit. In our analysis, we focus only on the bosonic part of the full superstring action and compute the relevant limits on both ( R × S 3) η and ( R × S 5) η models. The resulting system reveals that in the fast spinning limit, the sigma model on η deformed S 5 could be approximately thought of as the continuum limit of anisotropic SU(3) Heisenberg spin chain model. We compute the energy for a certain class of spinning strings in deformed S 5 and we show that this energy can be mapped to that of a similar spinning string in the purely imaginary β deformed background.

Cross-layer model design in wireless ad hoc networks for the Internet of Things.

PubMed

Yang, Xin; Wang, Ling; Xie, Jian; Zhang, Zhaolin

2018-01-01

Wireless ad hoc networks can experience extreme fluctuations in transmission traffic in the Internet of Things, which is widely used today. Currently, the most crucial issues requiring attention for wireless ad hoc networks are making the best use of low traffic periods, reducing congestion during high traffic periods, and improving transmission performance. To solve these problems, the present paper proposes a novel cross-layer transmission model based on decentralized coded caching in the physical layer and a content division multiplexing scheme in the media access control layer. Simulation results demonstrate that the proposed model effectively addresses these issues by substantially increasing the throughput and successful transmission rate compared to existing protocols without a negative influence on delay, particularly for large scale networks under conditions of highly contrasting high and low traffic periods.

Cross-layer model design in wireless ad hoc networks for the Internet of Things

PubMed Central

Wang, Ling; Xie, Jian; Zhang, Zhaolin

2018-01-01

Wireless ad hoc networks can experience extreme fluctuations in transmission traffic in the Internet of Things, which is widely used today. Currently, the most crucial issues requiring attention for wireless ad hoc networks are making the best use of low traffic periods, reducing congestion during high traffic periods, and improving transmission performance. To solve these problems, the present paper proposes a novel cross-layer transmission model based on decentralized coded caching in the physical layer and a content division multiplexing scheme in the media access control layer. Simulation results demonstrate that the proposed model effectively addresses these issues by substantially increasing the throughput and successful transmission rate compared to existing protocols without a negative influence on delay, particularly for large scale networks under conditions of highly contrasting high and low traffic periods. PMID:29734355

Multi-Skyrmions on AdS2 × S2, rational maps and popcorn transitions

NASA Astrophysics Data System (ADS)

Canfora, Fabrizio; Tallarita, Gianni

2017-08-01

By combining two different techniques to construct multi-soliton solutions of the (3 + 1)-dimensional Skyrme model, the generalized hedgehog and the rational map ansatz, we find multi-Skyrmion configurations in AdS2 ×S2. We construct Skyrmionic multi-layered configurations such that the total Baryon charge is the product of the number of kinks along the radial AdS2 direction and the degree of the rational map. We show that, for fixed total Baryon charge, as one increases the charge density on ∂ (AdS2 ×S2) , it becomes increasingly convenient energetically to have configurations with more peaks in the radial AdS2 direction but a lower degree of the rational map. This has a direct relation with the so-called holographic popcorn transitions in which, when the charge density is high, multi-layered configurations with low charge on each layer are favored over configurations with few layers but with higher charge on each layer. The case in which the geometry is M2 ×S2 can also be analyzed.

Hubble induced mass after inflation in spectator field models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fujita, Tomohiro; Harigaya, Keisuke, E-mail: tomofuji@stanford.edu, E-mail: keisukeh@icrr.u-tokyo.ac.jp

2016-12-01

Spectator field models such as the curvaton scenario and the modulated reheating are attractive scenarios for the generation of the cosmic curvature perturbation, as the constraints on inflation models are relaxed. In this paper, we discuss the effect of Hubble induced masses on the dynamics of spectator fields after inflation. We pay particular attention to the Hubble induced mass by the kinetic energy of an oscillating inflaton, which is generically unsuppressed but often overlooked. In the curvaton scenario, the Hubble induced mass relaxes the constraint on the property of the inflaton and the curvaton, such as the reheating temperature andmore » the inflation scale. We comment on the implication of our discussion for baryogenesis in the curvaton scenario. In the modulated reheating, the predictions of models e.g. the non-gaussianity can be considerably altered. Furthermore, we propose a new model of the modulated reheating utilizing the Hubble induced mass which realizes a wide range of the local non-gaussianity parameter.« less

Holographic thermalization and generalized Vaidya-AdS solutions in massive gravity

NASA Astrophysics Data System (ADS)

Hu, Ya-Peng; Zeng, Xiao-Xiong; Zhang, Hai-Qing

2017-02-01

We investigate the effect of massive graviton on the holographic thermalization process. Before doing this, we first find out the generalized Vaidya-AdS solutions in the de Rham-Gabadadze-Tolley (dRGT) massive gravity by directly solving the gravitational equations. Then, we study the thermodynamics of these Vaidya-AdS solutions by using the Misner-Sharp energy and unified first law, which also shows that the massive gravity is in a thermodynamic equilibrium state. Moreover, we adopt the two-point correlation function at equal time to explore the thermalization process in the dual field theory, and to see how the graviton mass parameter affects this process from the viewpoint of AdS/CFT correspondence. Our results show that the graviton mass parameter will increase the holographic thermalization process.

Exact Mass-Coupling Relation for the Homogeneous Sine-Gordon Model.

PubMed

Bajnok, Zoltán; Balog, János; Ito, Katsushi; Satoh, Yuji; Tóth, Gábor Zsolt

2016-05-06

We derive the exact mass-coupling relation of the simplest multiscale quantum integrable model, i.e., the homogeneous sine-Gordon model with two mass scales. The relation is obtained by comparing the perturbed conformal field theory description of the model valid at short distances to the large distance bootstrap description based on the model's integrability. In particular, we find a differential equation for the relation by constructing conserved tensor currents, which satisfy a generalization of the Θ sum rule Ward identity. The mass-coupling relation is written in terms of hypergeometric functions.

Neutrino mass in flavor dependent gauged lepton model

NASA Astrophysics Data System (ADS)

Nomura, Takaaki; Okada, Hiroshi

2018-03-01

We study a neutrino model introducing an additional nontrivial gauged lepton symmetry where the neutrino masses are induced at two-loop level, while the first and second charged-leptons of the standard model are done at one-loop level. As a result of the model structure, we can predict one massless active neutrino, and there is a dark matter candidate. Then we discuss the neutrino mass matrix, muon anomalous magnetic moment, lepton flavor violations, oblique parameters, and relic density of dark matter, taking into account the experimental constraints.

Examining impacts of mass-diameter (m-D) and area-diameter (A-D) relationships of ice particles on retrievals of effective radius and ice water content from radar and lidar measurements

NASA Astrophysics Data System (ADS)

Ham, Seung-Hee; Kato, Seiji; Rose, Fred G.

2017-03-01

Mass-diameter (m-D) and projected area-diameter (A-D) relations are often used to describe the shape of nonspherical ice particles. This study analytically investigates how retrieved effective radius (reff) and ice water content (IWC) from radar and lidar measurements depend on the assumption of m-D [m(D) = a Db] and A-D [A(D) = γ Dδ] relationships. We assume that unattenuated reflectivity factor (Z) and visible extinction coefficient (kext) by cloud particles are available from the radar and lidar measurements, respectively. A sensitivity test shows that reff increases with increasing a, decreasing b, decreasing γ, and increasing δ. It also shows that a 10% variation of a, b, γ, and δ induces more than a 100% change of reff. In addition, we consider both gamma and lognormal particle size distributions (PSDs) and examine the sensitivity of reff to the assumption of PSD. It is shown that reff increases by up to 10% with increasing dispersion (μ) of the gamma PSD by 2, when large ice particles are predominant. Moreover, reff decreases by up to 20% with increasing the width parameter (ω) of the lognormal PSD by 0.1. We also derive an analytic conversion equation between two effective radii when different particle shapes and PSD assumptions are used. When applying the conversion equation to nine types of m-D and A-D relationships, reff easily changes up to 30%. The proposed reff conversion method can be used to eliminate the inconsistency of assumptions that made in a cloud retrieval algorithm and a forward radiative transfer model.

Steady state phosphorus mass balance model during hemodialysis based on a pseudo one-compartment kinetic model.

PubMed

Leypoldt, John K; Agar, Baris U; Akonur, Alp; Gellens, Mary E; Culleton, Bruce F

2012-11-01

Mathematical models of phosphorus kinetics and mass balance during hemodialysis are in early development. We describe a theoretical phosphorus steady state mass balance model during hemodialysis based on a novel pseudo one-compartment kinetic model. The steady state mass balance model accounted for net intestinal absorption of phosphorus and phosphorus removal by both dialysis and residual kidney function. Analytical mathematical solutions were derived to describe time-dependent intradialytic and interdialytic serum phosphorus concentrations assuming hemodialysis treatments were performed symmetrically throughout a week. Results from the steady state phosphorus mass balance model are described for thrice weekly hemodialysis treatment prescriptions only. The analysis predicts 1) a minimal impact of dialyzer phosphorus clearance on predialysis serum phosphorus concentration using modern, conventional hemodialysis technology, 2) variability in the postdialysis-to-predialysis phosphorus concentration ratio due to differences in patient-specific phosphorus mobilization, and 3) the importance of treatment time in determining the predialysis serum phosphorus concentration. We conclude that a steady state phosphorus mass balance model can be developed based on a pseudo one-compartment kinetic model and that predictions from this model are consistent with previous clinical observations. The predictions from this mass balance model are theoretical and hypothesis-generating only; additional prospective clinical studies will be required for model confirmation.

Simple Decision-Analytic Functions of the AUC for Ruling Out a Risk Prediction Model and an Added Predictor.

PubMed

Baker, Stuart G

2018-02-01

When using risk prediction models, an important consideration is weighing performance against the cost (monetary and harms) of ascertaining predictors. The minimum test tradeoff (MTT) for ruling out a model is the minimum number of all-predictor ascertainments per correct prediction to yield a positive overall expected utility. The MTT for ruling out an added predictor is the minimum number of added-predictor ascertainments per correct prediction to yield a positive overall expected utility. An approximation to the MTT for ruling out a model is 1/[P (H(AUC model )], where H(AUC) = AUC - {½ (1-AUC)} ½ , AUC is the area under the receiver operating characteristic (ROC) curve, and P is the probability of the predicted event in the target population. An approximation to the MTT for ruling out an added predictor is 1 /[P {(H(AUC Model:2 ) - H(AUC Model:1 )], where Model 2 includes an added predictor relative to Model 1. The latter approximation requires the Tangent Condition that the true positive rate at the point on the ROC curve with a slope of 1 is larger for Model 2 than Model 1. These approximations are suitable for back-of-the-envelope calculations. For example, in a study predicting the risk of invasive breast cancer, Model 2 adds to the predictors in Model 1 a set of 7 single nucleotide polymorphisms (SNPs). Based on the AUCs and the Tangent Condition, an MTT of 7200 was computed, which indicates that 7200 sets of SNPs are needed for every correct prediction of breast cancer to yield a positive overall expected utility. If ascertaining the SNPs costs $500, this MTT suggests that SNP ascertainment is not likely worthwhile for this risk prediction.

Charge loss (or the lack thereof) for AdS black holes

NASA Astrophysics Data System (ADS)

Ong, Yen Chin; Chen, Pisin

2014-06-01

The evolution of evaporating charged black holes is complicated to model in general, but is nevertheless important since the hints to the Information Loss Paradox and its recent firewall incarnation may lie in understanding more generic geometries than that of Schwarzschild spacetime. Fortunately, for sufficiently large asymptotically flat Reissner-Nordström black holes, the evaporation process can be modeled via a system of coupled linear ordinary differential equations, with charge loss rate governed by Schwinger pair-production process. The same model can be generalized to study the evaporation of AdS Reissner-Nordström black holes with flat horizon. It was recently found that such black holes always evolve towards extremality since charge loss is inefficient. This property is completely opposite to the asymptotically flat case in which the black hole eventually loses its charges and tends towards Schwarzschild limit. We clarify the underlying reason for this different behavior.

High-mass X-ray binary populations. 1: Galactic modeling

NASA Technical Reports Server (NTRS)

Dalton, William W.; Sarazin, Craig L.

1995-01-01

Modern stellar evolutionary tracks are used to calculate the evolution of a very large number of massive binary star systems (M(sub tot) greater than or = 15 solar mass) which cover a wide range of total masses, mass ratios, and starting separations. Each binary is evolved accounting for mass and angular momentum loss through the supernova of the primary to the X-ray binary phase. Using the observed rate of star formation in our Galaxy and the properties of massive binaries, we calculate the expected high-mass X-ray binary (HMXRB) population in the Galaxy. We test various massive binary evolutionary scenarios by comparing the resulting HMXRB predictions with the X-ray observations. A major goal of this study is the determination of the fraction of matter lost from the system during the Roche lobe overflow phase. Curiously, we find that the total numbers of observable HMXRBs are nearly independent of this assumed mass-loss fraction, with any of the values tested here giving acceptable agreement between predicted and observed numbers. However, comparison of the period distribution of our HMXRB models with the observed period distribution does reveal a distinction among the various models. As a result of this comparison, we conclude that approximately 70% of the overflow matter is lost from a massive binary system during mass transfer in the Roche lobe overflow phase. We compare models constructed assuming that all X-ray emission is due to accretion onto the compact object from the donor star's wind with models that incorporate a simplified disk accretion scheme. By comparing the results of these models with observations, we conclude that the formation of disks in HMXRBs must be relatively common. We also calculate the rate of formation of double degenerate binaries, high velocity detached compact objects, and Thorne-Zytkow objects.

Value-Added Models for Teacher Preparation Programs: Validity and Reliability Threats, and a Manageable Alternative

ERIC Educational Resources Information Center

Brady, Michael P.; Heiser, Lawrence A.; McCormick, Jazarae K.; Forgan, James

2016-01-01

High-stakes standardized student assessments are increasingly used in value-added evaluation models to connect teacher performance to P-12 student learning. These assessments are also being used to evaluate teacher preparation programs, despite validity and reliability threats. A more rational model linking student performance to candidates who…

Milky Way Mass Models and MOND

NASA Astrophysics Data System (ADS)

McGaugh, Stacy S.

2008-08-01

Using the Tuorla-Heidelberg model for the mass distribution of the Milky Way, I determine the rotation curve predicted by MOND (modified Newtonian dynamics). The result is in good agreement with the observed terminal velocities interior to the solar radius and with estimates of the Galaxy's rotation curve exterior thereto. There are no fit parameters: given the mass distribution, MOND provides a good match to the rotation curve. The Tuorla-Heidelberg model does allow for a variety of exponential scale lengths; MOND prefers short scale lengths in the range 2.0 kpc lesssim Rdlesssim 2.5 kpc. The favored value of Rd depends somewhat on the choice of interpolation function. There is some preference for the "simple" interpolation function as found by Famaey & Binney. I introduce an interpolation function that shares the advantages of the simple function on galaxy scales while having a much smaller impact in the solar system. I also solve the inverse problem, inferring the surface mass density distribution of the Milky Way from the terminal velocities. The result is a Galaxy with "bumps and wiggles" in both its luminosity profile and rotation curve that are reminiscent of those frequently observed in external galaxies.

A high resolution model of linear trend in mass variations from DMT-2: Added value of accounting for coloured noise in GRACE data

NASA Astrophysics Data System (ADS)

Farahani, Hassan H.; Ditmar, Pavel; Inácio, Pedro; Didova, Olga; Gunter, Brian; Klees, Roland; Guo, Xiang; Guo, Jing; Sun, Yu; Liu, Xianglin; Zhao, Qile; Riva, Riccardo

2017-01-01

We present a high resolution model of the linear trend in the Earth's mass variations based on DMT-2 (Delft Mass Transport model, release 2). DMT-2 was produced primarily from K-Band Ranging (KBR) data of the Gravity Recovery And Climate Experiment (GRACE). It comprises a time series of monthly solutions complete to spherical harmonic degree 120. A novel feature in its production was the accurate computation and incorporation of stochastic properties of coloured noise when processing KBR data. The unconstrained DMT-2 monthly solutions are used to estimate the linear trend together with a bias, as well as annual and semi-annual sinusoidal terms. The linear term is further processed with an anisotropic Wiener filter, which uses full noise and signal covariance matrices. Given the fact that noise in an unconstrained model of the trend is reduced substantially as compared to monthly solutions, the Wiener filter associated with the trend is much less aggressive compared to a Wiener filter applied to monthly solutions. Consequently, the trend estimate shows an enhanced spatial resolution. It allows signals in relatively small water bodies, such as Aral sea and Ladoga lake, to be detected. Over the ice sheets, it allows for a clear identification of signals associated with some outlet glaciers or their groups. We compare the obtained trend estimate with the ones from the CSR-RL05 model using (i) the same approach based on monthly noise covariance matrices and (ii) a commonly-used approach based on the DDK-filtered monthly solutions. We use satellite altimetry data as independent control data. The comparison demonstrates a high spatial resolution of the DMT-2 linear trend. We link this to the usage of high-accuracy monthly noise covariance matrices, which is due to an accurate computation and incorporation of coloured noise when processing KBR data. A preliminary comparison of the linear trend based on DMT-2 with that computed from GSFC_global_mascons_v01 reveals, among

Dependence of X-Ray Burst Models on Nuclear Masses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schatz, H.; Ong, W.-J.

X-ray burst model predictions of light curves and the final composition of the nuclear ashes are affected by uncertain nuclear masses. However, not all of these masses are determined experimentally with sufficient accuracy. Here we identify the remaining nuclear mass uncertainties in X-ray burst models using a one-zone model that takes into account the changes in temperature and density evolution caused by changes in the nuclear physics. Two types of bursts are investigated—a typical mixed H/He burst with a limited rapid proton capture process (rp-process) and an extreme mixed H/He burst with an extended rp-process. When allowing for a 3more » σ variation, only three remaining nuclear mass uncertainties affect the light-curve predictions of a typical H/He burst ({sup 27}P, {sup 61}Ga, and {sup 65}As), and only three additional masses affect the composition strongly ({sup 80}Zr, {sup 81}Zr, and {sup 82}Nb). A larger number of mass uncertainties remain to be addressed for the extreme H/He burst, with the most important being {sup 58}Zn, {sup 61}Ga, {sup 62}Ge, {sup 65}As, {sup 66}Se, {sup 78}Y, {sup 79}Y, {sup 79}Zr, {sup 80}Zr, {sup 81}Zr, {sup 82}Zr, {sup 82}Nb, {sup 83}Nb, {sup 86}Tc, {sup 91}Rh, {sup 95}Ag, {sup 98}Cd, {sup 99}In, {sup 100}In, and {sup 101}In. The smallest mass uncertainty that still impacts composition significantly when varied by 3 σ is {sup 85}Mo with 16 keV uncertainty. For one of the identified masses, {sup 27}P, we use the isobaric mass multiplet equation to improve the mass uncertainty, obtaining an atomic mass excess of −716(7) keV. The results provide a roadmap for future experiments at advanced rare isotope beam facilities, where all the identified nuclides are expected to be within reach for precision mass measurements.« less

Applying an orographic precipitation model to improve mass balance modeling of the Juneau Icefield, AK

NASA Astrophysics Data System (ADS)

Roth, A. C.; Hock, R.; Schuler, T.; Bieniek, P.; Aschwanden, A.

2017-12-01

Mass loss from glaciers in Southeast Alaska is expected to alter downstream ecological systems as runoff patterns change. To investigate these potential changes under future climate scenarios, distributed glacier mass balance modeling is required. However, the spatial resolution gap between global or regional climate models and the requirements for glacier mass balance modeling studies must be addressed first. We have used a linear theory of orographic precipitation model to downscale precipitation from both the Weather Research and Forecasting (WRF) model and ERA-Interim to the Juneau Icefield region over the period 1979-2013. This implementation of the LT model is a unique parameterization that relies on the specification of snow fall speed and rain fall speed as tuning parameters to calculate the cloud time delay, τ. We assessed the LT model results by considering winter precipitation so the effect of melt was minimized. The downscaled precipitation pattern produced by the LT model captures the orographic precipitation pattern absent from the coarse resolution WRF and ERA-Interim precipitation fields. Observational data constraints limited our ability to determine a unique parameter combination and calibrate the LT model to glaciological observations. We established a reference run of parameter values based on literature and performed a sensitivity analysis of the LT model parameters, horizontal resolution, and climate input data on the average winter precipitation. The results of the reference run showed reasonable agreement with the available glaciological measurements. The precipitation pattern produced by the LT model was consistent regardless of parameter combination, horizontal resolution, and climate input data, but the precipitation amount varied strongly with these factors. Due to the consistency of the winter precipitation pattern and the uncertainty in precipitation amount, we suggest a precipitation index map approach to be used in combination with

Associations between Student Achievement and Student Learning: Implications for Value-Added School Accountability Models

ERIC Educational Resources Information Center

Ready, Douglas David

2013-01-01

Accountability systems that measure student learning rather than student achievement have the potential to more accurately evaluate school quality. However, one methodological concern has remained surprisingly absent from discussions of value-added modeling. Standardized assessments that exhibit either positive or negative correlations between…

The Use of a School Value-Added Model for Educational Improvement: A Case Study from the Portuguese Primary Education System

ERIC Educational Resources Information Center

Ferrão, Maria Eugénia; Couto, Alcino Pinto

2014-01-01

This article focuses on the use of a value-added approach for promoting school improvement. It presents yearly value-added estimates, analyses their stability over time, and discusses the contribution of this methodological approach for promoting school improvement programmes in the Portuguese system of evaluation. The value-added model is applied…

The simultaneous mass and energy evaporation (SM2E) model.

PubMed

Choudhary, Rehan; Klauda, Jeffery B

2016-01-01

In this article, the Simultaneous Mass and Energy Evaporation (SM2E) model is presented. The SM2E model is based on theoretical models for mass and energy transfer. The theoretical models systematically under or over predicted at various flow conditions: laminar, transition, and turbulent. These models were harmonized with experimental measurements to eliminate systematic under or over predictions; a total of 113 measured evaporation rates were used. The SM2E model can be used to estimate evaporation rates for pure liquids as well as liquid mixtures at laminar, transition, and turbulent flow conditions. However, due to limited availability of evaporation data, the model has so far only been tested against data for pure liquids and binary mixtures. The model can take evaporative cooling into account and when the temperature of the evaporating liquid or liquid mixture is known (e.g., isothermal evaporation), the SM2E model reduces to a mass transfer-only model.

A mass-conserving multiphase lattice Boltzmann model for simulation of multiphase flows

NASA Astrophysics Data System (ADS)

Niu, Xiao-Dong; Li, You; Ma, Yi-Ren; Chen, Mu-Feng; Li, Xiang; Li, Qiao-Zhong

2018-01-01

In this study, a mass-conserving multiphase lattice Boltzmann (LB) model is proposed for simulating the multiphase flows. The proposed model developed in the present study is to improve the model of Shao et al. ["Free-energy-based lattice Boltzmann model for simulation of multiphase flows with density contrast," Phys. Rev. E 89, 033309 (2014)] by introducing a mass correction term in the lattice Boltzmann model for the interface. The model of Shao et al. [(the improved Zheng-Shu-Chew (Z-S-C model)] correctly considers the effect of the local density variation in momentum equation and has an obvious improvement over the Zheng-Shu-Chew (Z-S-C) model ["A lattice Boltzmann model for multiphase flows with large density ratio," J. Comput. Phys. 218(1), 353-371 (2006)] in terms of solution accuracy. However, due to the physical diffusion and numerical dissipation, the total mass of each fluid phase cannot be conserved correctly. To solve this problem, a mass correction term, which is similar to the one proposed by Wang et al. ["A mass-conserved diffuse interface method and its application for incompressible multiphase flows with large density ratio," J. Comput. Phys. 290, 336-351 (2015)], is introduced into the lattice Boltzmann equation for the interface to compensate the mass losses or offset the mass increase. Meanwhile, to implement the wetting boundary condition and the contact angle, a geometric formulation and a local force are incorporated into the present mass-conserving LB model. The proposed model is validated by verifying the Laplace law, simulating both one and two aligned droplets splashing onto a liquid film, droplets standing on an ideal wall, droplets with different wettability splashing onto smooth wax, and bubbles rising under buoyancy. Numerical results show that the proposed model can correctly simulate multiphase flows. It was found that the mass is well-conserved in all cases considered by the model developed in the present study. The developed

Beyond AdS Space-times, New Holographic Correspondences and Applications

NASA Astrophysics Data System (ADS)

Ghodrati, Mahdis

The AdS/CFT correspondence conjectures a mathematical equivalence between string theories and gauge theories. In a particular limit it allows a description of strongly coupled conformal field theory via weakly coupled gravity. This feature has been used to gain insight into many condensed matter (CM) systems. However, to apply the duality in more physical scenarios, one needs to go beyond the usual AdS/CFT framework and extend the duality to non-AdS situations. To describe Lifshitz and hyperscaling violating (HSV) phenomena in CM one uses gauge fields on the gravity side which naturally realize the breaking of Lorentz invariance. These gravity constructions often contain naked singularities. In this thesis, we construct a resolution of the infra-red (IR) singularity of the HSV background. The idea is to add squared curvature terms to the Einstein-Maxwell dilaton action to build a flow from AdS4 in the ultra violate (UV) to an intermediating HSV region and then to an AdS2 x R 2 region in the IR. This general solution is free from the naked singularities and would be more appropriate for applications of HSV in physical systems. We also study the Schwinger effect by using the AdS/CFT duality. We present the phase diagrams of the Schwinger effect and also the "butterfly shaped-phase diagrams" of the entanglement entropy for four different confining supergravity backgrounds. Comparing different features of all of these diagrams could point out to a potential relation between the Schwinger effect and the entanglement entropy which could lead to a method of measuring entanglement entropy in the laboratory. Finally, we study the "new massive gravity" theory and the different black hole solutions it admits. We first present three different methods of calculating the conserved charges. Then, by calculating the on-shell Gibbs free energy we construct the Hawking-Page phase diagrams for different solutions in two thermodynamical ensembles. As the massive gravity models are

Distinct chronology of neuronal cell cycle re-entry and tau pathology in the 3xTg-AD mouse model and Alzheimer's disease patients.

PubMed

Hradek, Alex C; Lee, Hyun-Pil; Siedlak, Sandra L; Torres, Sandy L; Jung, Wooyoung; Han, Ashley H; Lee, Hyoung-gon

2015-01-01

Cell cycle re-entry in Alzheimer's disease (AD) has emerged as an important pathological mechanism in the progression of the disease. This appearance of cell cycle related proteins has been linked to tau pathology in AD, but the causal and temporal relationship between the two is not completely clear. In this study, we found that hyperphosphorylated retinoblastoma protein (ppRb), a key regulator for G1/S transition, is correlated with a late marker for hyperphosphorylation of tau but not with other early markers for tau alteration in the 3xTg-AD mouse model. However, in AD brains, ppRb can colocalize with both early and later markers for tau alterations, and can often be found singly in many degenerating neurons, indicating the distinct development of pathology between the 3xTg-AD mouse model and human AD patients. The conclusions of this study are two-fold. First, our findings clearly demonstrate the pathological link between the aberrant cell cycle re-entry and tau pathology. Second, the chronological pattern of cell cycle re-entry with tau pathology in the 3xTg-AD mouse is different compared to AD patients suggesting the distinct pathogenic mechanism between the animal AD model and human AD patients.

Mass spectrometry and tandem mass spectrometry of citrus limonoids.

PubMed

Tian, Qingguo; Schwartz, Steven J

2003-10-15

Methods for atmospheric pressure chemical ionization tandem mass spectrometry (APCI-MS/MS) of citrus limonoid aglycones and electrospray ionization tandem mass spectrometry (ESI-MS/MS) of limonoid glucosides are reported. The fragmentation patterns of four citrus limonoid aglycones (limonin, nomilin, obacunone, and deacetylnomilin) and six limonoid glucosides, that is, limonin 17-beta-D-glucopyranoside (LG), nomilin 17-beta-D-glucopyranoside (NG), nomilinic acid 17-beta-D-glucopyranoside (NAG), deacetyl nomilinic acid 17-beta-D-glucopyranoside (DNAG), obacunone 17-beta-D-glucopyranoside (OG), and obacunoic acid 17-beta-D-glucopyranoside (OAG) were investigated using a quadruple mass spectrometer in low-energy collisionally activated dissociation (CAD). The four limonoid aglycones and four limonoid glucosides (LG, OG, NAG, and DNAG) were purified from citrus seeds; the other two limonoid glucosides (NG and OAG) were tentatively identified in the crude extract of grapefruit seeds by ESI mass spectrometry in both positive and negative ion analysis. Ammonium hydroxide or acetic acid was added to the mobile phase to facilitate ionization. During positive ion APCI analysis of limonoid aglycones, protonated molecular ion, [M + H]+, or adduct ion, [M + NH3 + H]-, was formed as base peaks when ammonium hydroxide was added to the mobile phase. Molecular anions or adduct ions with acetic acid ([M + HOAc - H] and [M + HOAc]-) or a deprotonated molecular ion were produced during negative ion APCI analysis of limonoid aglycones, depending on the mobile-phase modifier used. Positive ion ESI-MS of limonoid glucosides produced adduct ions of [M + H + NH3]+, [M + Na]+, and [M + K]+ when ammonium hydroxide was added to the mobile phase. After collisionally activated dissociation (CAD) of the limonoid aglycone molecular ions in negative ion APCI analysis, fragment ions indicated structural information of the precursor ions, showing the presence of methyl, carboxyl, and oxygenated ring

Development and validation of a mass casualty conceptual model.

PubMed

Culley, Joan M; Effken, Judith A

2010-03-01

To develop and validate a conceptual model that provides a framework for the development and evaluation of information systems for mass casualty events. The model was designed based on extant literature and existing theoretical models. A purposeful sample of 18 experts validated the model. Open-ended questions, as well as a 7-point Likert scale, were used to measure expert consensus on the importance of each construct and its relationship in the model and the usefulness of the model to future research. Computer-mediated applications were used to facilitate a modified Delphi technique through which a panel of experts provided validation for the conceptual model. Rounds of questions continued until consensus was reached, as measured by an interquartile range (no more than 1 scale point for each item); stability (change in the distribution of responses less than 15% between rounds); and percent agreement (70% or greater) for indicator questions. Two rounds of the Delphi process were needed to satisfy the criteria for consensus or stability related to the constructs, relationships, and indicators in the model. The panel reached consensus or sufficient stability to retain all 10 constructs, 9 relationships, and 39 of 44 indicators. Experts viewed the model as useful (mean of 5.3 on a 7-point scale). Validation of the model provides the first step in understanding the context in which mass casualty events take place and identifying variables that impact outcomes of care. This study provides a foundation for understanding the complexity of mass casualty care, the roles that nurses play in mass casualty events, and factors that must be considered in designing and evaluating information-communication systems to support effective triage under these conditions.

Type IIB supergravity solution for the T-dual of the η-deformed AdS 5 × S 5 superstring

NASA Astrophysics Data System (ADS)

Hoare, B.; Tseytlin, A. A.

2015-10-01

We find an exact type IIB supergravity solution that represents a one-parameter deformation of the T-dual of the AdS 5 × S 5 background (with T-duality applied in all 6 abelian bosonic isometric directions). The non-trivial fields are the metric, dilaton and RR 5-form only. The latter has remarkably simple "undeformed" form when written in terms of a "deformation-rotated" vielbein basis. An unusual feature of this solution is that the dilaton contains a linear dependence on the isometric coordinates of the metric precluding a straightforward reversal of T-duality. If we still formally dualize back, we find exactly the metric, B-field and product of dilaton with RR field strengths as recently extracted from the η-deformed AdS 5 × S 5 superstring action in arXiv:1507.04239. We also discuss similar solutions for deformed AdS n × S n backgrounds with n = 2 , 3. In the η → i limit we demonstrate that all these backgrounds can be interpreted as special limits of gauged WZW models and are also related to (a limit of) the Pohlmeyer-reduced models of the AdS n × S n superstrings.

Mass segregation phenomena using the Hamiltonian Mean Field model

NASA Astrophysics Data System (ADS)

Steiner, J. R.; Zolacir, T. O.

2018-02-01

Mass segregation problem is thought to be entangled with the dynamical evolution of young stellar clusters (Olczak, 2011 [1]). This is a common sense in the astrophysical community. In this work, the Hamiltonian Mean Field (HMF) model with different masses is studied. A mass segregation phenomenon (MSP) arises from this study as a dynamical feature. The MSP in the HMF model is a consequence of the Landau damping (LD) and it appears in systems that the interactions belongs to a long range regime. Actually HMF is a toy model known to show up the main characteristics of astrophysical systems due to the mean field character of the potential and for different masses, as stellar and galaxies clusters, also exhibits MSP. It is in this sense that computational simulations focusing in what happens over the mass distribution in the phase space are performed for this system. What happens through the violent relaxation period and what stands for the quasi-stationary states (QSS) of this dynamics is analyzed. The results obtained support the fact that MSP is observed already in the violent relaxation time and is maintained during the QSS. Some structures in the mass distribution function are observed. As a result of this study the mass distribution is determined by the system dynamics and is independent of the dimensionality of the system. MSP occurs in a one dimensional system as a result of the long range forces that acts in the system. In this approach MSP emerges as a dynamical feature. We also show that for HMF with different masses, the dynamical time scale is N.

Constraints on texture zero and cofactor zero models for neutrino mass

DOE Office of Scientific and Technical Information (OSTI.GOV)

Whisnant, K.; Liao, Jiajun; Marfatia, D.

2014-06-24

Imposing a texture or cofactor zero on the neutrino mass matrix reduces the number of independent parameters from nine to seven. Since five parameters have been measured, only two independent parameters would remain in such models. We find the allowed regions for single texture zero and single cofactor zero models. We also find strong similarities between single texture zero models with one mass hierarchy and single cofactor zero models with the opposite mass hierarchy. We show that this correspondence can be generalized to texture-zero and cofactor-zero models with the same homogeneous costraints on the elements and cofactors.

Comprehensive and critical review of the predictive properties of the various mass models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haustein, P.E.

1984-01-01

Since the publication of the 1975 Mass Predictions approximately 300 new atomic masses have been reported. These data come from a variety of experimental studies using diverse techniques and they span a mass range from the lightest isotopes to the very heaviest. It is instructive to compare these data with the 1975 predictions and several others (Moeller and Nix, Monahan, Serduke, Uno and Yamada which appeared latter. Extensive numerical and graphical analyses have been performed to examine the quality of the mass predictions from the various models and to identify features in these models that require correction. In general, theremore » is only rough correlation between the ability of a particular model to reproduce the measured mass surface which had been used to refine its adjustable parameters and that model's ability to predict correctly the new masses. For some models distinct systematic features appear when the new mass data are plotted as functions of relevant physical variables. Global intercomparisons of all the models are made first, followed by several examples of types of analysis performed with individual mass models.« less

AdS/CFT beyond the N = 4 SYM paradigm

NASA Astrophysics Data System (ADS)

Pomoni, Elli

In this thesis we present studies in the AdS/CFT correspondence that intend to push the present knowledge beyond the N = 4 super Yang-Mills (SYM) paradigm. The first part is concerned with the study of non-supersymmetric deformations of N = 4 SYM (which still are in the N = 4 universality class). For non-supersymmetric CFT's at Large N we explore the correspondence between string theory tachyons in the bulk and instabilities on the boundary effective action. The operators dual to AdS tachyons have anomalous dimensions that are purely complex numbers. We give a prescription for calculating the mass of the tachyon from the field theory side. Moreover, we apply this general dictionary to the case of intersecting D7 flavor branes in AdS 5 x S5 and obtain the mass of the open string tachyon that is dual to the instability in the mesonic sector of the theory. In the second part we present work aiming at finding string theory duals for gauge theories beyond the N = 4 universality class, i.e. theories that have genuinely less supersymmetry and unquenched flavor. Arguably the next simplest example after N = 4 SYM is N = 2 SU(Nc) SYM coupled to Nf = 2Nc fundamental hypermultiplets. The theory admits a Veneziano expansion of large Nc and large Nf, with Nf/Nc and lambda = g2Nc kept fixed. The topological structure of large N diagrams invites a general conjecture: the flavor-singlet sector of a gauge theory in the Veneziano limit is dual to a closed string theory. We present the one-loop Hamiltonian for the scalar sector of N = 2 superconformal QCD and study this integrability of the theory. Furthermore, we explore the chiral spectrum of the protected operators of the theory using the one-loop anomalous dimensions and, additionally, by studying the index of the theory. We finally search for possible AdS dual trying to match the chiral spectrum. We conclude that the string dual is a sub-critical background containing both an AdS 5 and an S1 factor.

Thermodynamics of charged Lovelock: AdS black holes

NASA Astrophysics Data System (ADS)

Prasobh, C. B.; Suresh, Jishnu; Kuriakose, V. C.

2016-04-01

We investigate the thermodynamic behavior of maximally symmetric charged, asymptotically AdS black hole solutions of Lovelock gravity. We explore the thermodynamic stability of such solutions by the ordinary method of calculating the specific heat of the black holes and investigating its divergences which signal second-order phase transitions between black hole states. We then utilize the methods of thermodynamic geometry of black hole spacetimes in order to explain the origin of these points of divergence. We calculate the curvature scalar corresponding to a Legendre-invariant thermodynamic metric of these spacetimes and find that the divergences in the black hole specific heat correspond to singularities in the thermodynamic phase space. We also calculate the area spectrum for large black holes in the model by applying the Bohr-Sommerfeld quantization to the adiabatic invariant calculated for the spacetime.

Fine Grained Chaos in AdS2 Gravity

NASA Astrophysics Data System (ADS)

Haehl, Felix M.; Rozali, Moshe

2018-03-01

Quantum chaos can be characterized by an exponential growth of the thermal out-of-time-order four-point function up to a scrambling time u^*. We discuss generalizations of this statement for certain higher-point correlation functions. For concreteness, we study the Schwarzian theory of a one-dimensional time reparametrization mode, which describes two-dimensional anti-de Sitter space (AdS2 ) gravity and the low-energy dynamics of the Sachdev-Ye-Kitaev model. We identify a particular set of 2 k -point functions, characterized as being both "maximally braided" and "k -out of time order," which exhibit exponential growth until progressively longer time scales u^*(k)˜(k -1 )u^*. We suggest an interpretation as scrambling of increasingly fine grained measures of quantum information, which correspondingly take progressively longer time to reach their thermal values.

Fine Grained Chaos in AdS_{2} Gravity.

PubMed

Haehl, Felix M; Rozali, Moshe

2018-03-23

Quantum chaos can be characterized by an exponential growth of the thermal out-of-time-order four-point function up to a scrambling time u[over ^]_{*}. We discuss generalizations of this statement for certain higher-point correlation functions. For concreteness, we study the Schwarzian theory of a one-dimensional time reparametrization mode, which describes two-dimensional anti-de Sitter space (AdS_{2}) gravity and the low-energy dynamics of the Sachdev-Ye-Kitaev model. We identify a particular set of 2k-point functions, characterized as being both "maximally braided" and "k-out of time order," which exhibit exponential growth until progressively longer time scales u[over ^]_{*}^{(k)}∼(k-1)u[over ^]_{*}. We suggest an interpretation as scrambling of increasingly fine grained measures of quantum information, which correspondingly take progressively longer time to reach their thermal values.

Modelling mass transfer during venting/soil vapour extraction: Non-aqueous phase liquid/gas mass transfer coefficient estimation

NASA Astrophysics Data System (ADS)

Esrael, D.; Kacem, M.; Benadda, B.

2017-07-01

We investigate how the simulation of the venting/soil vapour extraction (SVE) process is affected by the mass transfer coefficient, using a model comprising five partial differential equations describing gas flow and mass conservation of phases and including an expression accounting for soil saturation conditions. In doing so, we test five previously reported quations for estimating the non-aqueous phase liquid (NAPL)/gas initial mass transfer coefficient and evaluate an expression that uses a reference NAPL saturation. Four venting/SVE experiments utilizing a sand column are performed with dry and non-saturated sand at low and high flow rates, and the obtained experimental results are subsequently simulated, revealing that hydrodynamic dispersion cannot be neglected in the estimation of the mass transfer coefficient, particularly in the case of low velocities. Among the tested models, only the analytical solution of a convection-dispersion equation and the equation proposed herein are suitable for correctly modelling the experimental results, with the developed model representing the best choice for correctly simulating the experimental results and the tailing part of the extracted gas concentration curve.

Critical behavior and microscopic structure of charged AdS black holes via an alternative phase space

NASA Astrophysics Data System (ADS)

Dehyadegari, Amin; Sheykhi, Ahmad; Montakhab, Afshin

2017-05-01

It has been argued that charged Anti-de Sitter (AdS) black holes have similar thermodynamic behavior as the Van der Waals fluid system, provided one treats the cosmological constant as a thermodynamic variable (pressure) in an extended phase space. In this paper, we disclose the deep connection between charged AdS black holes and Van der Waals fluid system from an alternative point of view. We consider the mass of an AdS black hole as a function of square of the charge Q2 instead of the standard Q, i.e. M = M (S ,Q2 , P). We first justify such a change of view mathematically and then ask if a phase transition can occur as a function of Q2 for fixed P. Therefore, we write the equation of state as Q2 =Q2 (T , Ψ) where Ψ (conjugate of Q2) is the inverse of the specific volume, Ψ = 1 / v. This allows us to complete the analogy of charged AdS black holes with Van der Waals fluid system and derive the phase transition as well as critical exponents of the system. We identify a thermodynamic instability in this new picture with real analogy to Van der Waals fluid with physically relevant Maxwell construction. We therefore study the critical behavior of isotherms in Q2- Ψ diagram and deduce all the critical exponents of the system and determine that the system exhibits a small-large black hole phase transition at the critical point (Tc , Qc2 ,Ψc). This alternative view is important as one can imagine such a change for a given single black hole i.e. acquiring charge which induces the phase transition. Finally, we disclose the microscopic properties of charged AdS black holes by using thermodynamic geometry. Interestingly, we find that scalar curvature has a gap between small and large black holes, and this gap becomes exceedingly large as one moves away from the critical point along the transition line. Therefore, we are able to attribute the sudden enlargement of the black hole to the strong repulsive nature of the internal constituents at the phase transition.

Models for predicting the mass of lime fruits by some engineering properties.

PubMed

Miraei Ashtiani, Seyed-Hassan; Baradaran Motie, Jalal; Emadi, Bagher; Aghkhani, Mohammad-Hosein

2014-11-01

Grading fruits based on mass is important in packaging and reduces the waste, also increases the marketing value of agricultural produce. The aim of this study was mass modeling of two major cultivars of Iranian limes based on engineering attributes. Models were classified into three: 1-Single and multiple variable regressions of lime mass and dimensional characteristics. 2-Single and multiple variable regressions of lime mass and projected areas. 3-Single regression of lime mass based on its actual volume and calculated volume assumed as ellipsoid and prolate spheroid shapes. All properties considered in the current study were found to be statistically significant (ρ < 0.01). The results indicated that mass modeling of lime based on minor diameter and first projected area are the most appropriate models in the first and the second classifications, respectively. In third classification, the best model was obtained on the basis of the prolate spheroid volume. It was finally concluded that the suitable grading system of lime mass is based on prolate spheroid volume.

Modeling radiative transfer with the doubling and adding approach in a climate GCM setting

NASA Astrophysics Data System (ADS)

Lacis, A. A.

2017-12-01

The nonlinear dependence of multiply scattered radiation on particle size, optical depth, and solar zenith angle, makes accurate treatment of multiple scattering in the climate GCM setting problematic, due primarily to computational cost issues. In regard to the accurate methods of calculating multiple scattering that are available, their computational cost is far too prohibitive for climate GCM applications. Utilization of two-stream-type radiative transfer approximations may be computationally fast enough, but at the cost of reduced accuracy. We describe here a parameterization of the doubling/adding method that is being used in the GISS climate GCM, which is an adaptation of the doubling/adding formalism configured to operate with a look-up table utilizing a single gauss quadrature point with an extra-angle formulation. It is designed to closely reproduce the accuracy of full-angle doubling and adding for the multiple scattering effects of clouds and aerosols in a realistic atmosphere as a function of particle size, optical depth, and solar zenith angle. With an additional inverse look-up table, this single-gauss-point doubling/adding approach can be adapted to model fractional cloud cover for any GCM grid-box in the independent pixel approximation as a function of the fractional cloud particle sizes, optical depths, and solar zenith angle dependence.

Mass and heat transfer model of Tubular Solar Still

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ahsan, Amimul; Fukuhara, Teruyuki

2010-07-15

In this paper, a new mass and heat transfer model of a Tubular Solar Still (TSS) was proposed incorporating various mass and heat transfer coefficients taking account of the humid air properties inside the still. The heat balance of the humid air and the mass balance of the water vapor in the humid air were formulized for the first time. As a result, the proposed model enabled to calculate the diurnal variations of the temperature, water vapor density and relative humidity of the humid air, and to predict the hourly condensation flux besides the temperatures of the water, cover andmore » trough, and the hourly evaporation flux. The validity of the proposed model was verified using the field experimental results carried out in Fukui, Japan and Muscat, Oman in 2008. The diurnal variations of the calculated temperatures and water vapor densities had a good agreement with the observed ones. Furthermore, the proposed model can predict the daily and hourly production flux precisely. (author)« less

Testing Ultracool Models with Precise Luminosities and Masses

NASA Astrophysics Data System (ADS)

Dupuy, Trent; Cushing, Michael; Liu, Michael; Burningham, Ben; Leggett, Sandy; Albert, Loic; Delorme, Philippe

2011-05-01

After years of patient orbital monitoring, there is a growing sample of brown dwarfs with well-determined dynamical masses, representing the gold standard for testing substellar models. A key element of our model tests to date has been the use of integrated-light photometry to provide accurate total luminosity measurements for these binaries. However, some of the ultracool binaries with the most promising orbit motion for yielding dynamical in the masses lack the mid-infrared photometry needed to constrain their SEDs. This is especially crucial for the latest type binaries (spectral types >T5) that will probe the coldest temperature regimes previously untested with dynamical masses. We propose to use IRAC to obtain the needed mid-infrared photometry for a sample of binaries that are part of our ongoing orbital monitoring program with Keck laser guide star adaptive optics. The observational effort needed to characterize these binaries' luminosities using Spitzer is much less daunting in than the years of orbital monitoring needed to measure precise dynamical masses, but it is equally vital for robust tests of theory.

Inflammation, neurodegeneration and protein aggregation in the retina as ocular biomarkers for Alzheimer's disease in the 3xTg-AD mouse model.

PubMed

Grimaldi, Alfonso; Brighi, Carlo; Peruzzi, Giovanna; Ragozzino, Davide; Bonanni, Valentina; Limatola, Cristina; Ruocco, Giancarlo; Di Angelantonio, Silvia

2018-06-07

Alzheimer's disease (AD) is the most common cause of dementia in the elderly. In the pathogenesis of AD a pivotal role is played by two neurotoxic proteins that aggregate and accumulate in the central nervous system: amyloid beta and hyper-phosphorylated tau. Accumulation of extracellular amyloid beta plaques and intracellular hyper-phosphorylated tau tangles, and consequent neuronal loss begins 10-15 years before any cognitive impairment. In addition to cognitive and behavioral deficits, sensorial abnormalities have been described in AD patients and in some AD transgenic mouse models. Retina can be considered a simple model of the brain, as some pathological changes and therapeutic strategies from the brain may be observed or applicable to the retina. Here we propose new retinal biomarkers that could anticipate the AD diagnosis and help the beginning and the follow-up of possible future treatments. We analyzed retinal tissue of triple-transgenic AD mouse model (3xTg-AD) for the presence of pathological hallmarks during disease progression. We found the presence of amyloid beta plaques, tau tangles, neurodegeneration, and astrogliosis in the retinal ganglion cell layer of 3xTg-AD mice, already at pre-symptomatic stage. Moreover, retinal microglia in pre-symptomatic mice showed a ramified, anti-inflammatory phenotype which, during disease progression, switches to a pro-inflammatory, less ramified one, becoming neurotoxic. We hypothesize retina as a window through which monitor AD-related neurodegeneration process.

Evasion of added isotopic mercury from a northern temperate lake

USGS Publications Warehouse

Southworth, G.; Lindberg, S.; Hintelmann, H.; Amyot, M.; Poulain, A.; Bogle, M.; Peterson, M.; Rudd, J.; Harris, R.; Sandilands, K.; Krabbenhoft, D.; Olsen, M.

2007-01-01

Isotopically enriched Hg (90% 202Hg) was added to a small lake in Ontario, Canada, at a rate equivalent to approximately threefold the annual direct atmospheric deposition rate that is typical of the northeastern United States. The Hg spike was thoroughly mixed into the epilimnion in nine separate events at two-week intervals throughout the summer growing season for three consecutive years. We measured concentrations of spike and ambient dissolved gaseous Hg (DGM) concentrations in surface water and the rate of volatilization of Hg from the lake on four separate, week-long sampling periods using floating dynamic flux chambers. The relationship between empirically measured rates of spike-Hg evasion were evaluated as functions of DGM concentration, wind velocity, and solar illumination. No individual environmental variable proved to be a strong predictor of the evasion flux. The DGM-normalized flux (expressed as the mass transfer coefficient, k) varied with wind velocity in a manner consistent with existing models of evasion of volatile solutes from natural waters but was higher than model estimates at low wind velocity. The empirical data were used to construct a description of evasion flux as a function of total dissolved Hg, wind, and solar illumination. That model was then applied to data for three summers for the experiment to generate estimates of Hg re-emission from the lake surface to the atmosphere. Based on ratios of spike Hg to ambient Hg in DGM and dissolved total Hg pools, ratios of DGM to total Hg in spike and ambient Hg pools, and flux estimates of spike and ambient Hg, we concluded that the added Hg spike was chemically indistinguishable from the ambient Hg in its behavior. Approximately 45% of Hg added to the lake over the summer was lost via volatilization. ?? 2007 SETAC.

Model-Based Systems Engineering Approach to Managing Mass Margin

NASA Technical Reports Server (NTRS)

Chung, Seung H.; Bayer, Todd J.; Cole, Bjorn; Cooke, Brian; Dekens, Frank; Delp, Christopher; Lam, Doris

2012-01-01

When designing a flight system from concept through implementation, one of the fundamental systems engineering tasks ismanaging the mass margin and a mass equipment list (MEL) of the flight system. While generating a MEL and computing a mass margin is conceptually a trivial task, maintaining consistent and correct MELs and mass margins can be challenging due to the current practices of maintaining duplicate information in various forms, such as diagrams and tables, and in various media, such as files and emails. We have overcome this challenge through a model-based systems engineering (MBSE) approach within which we allow only a single-source-of-truth. In this paper we describe the modeling patternsused to capture the single-source-of-truth and the views that have been developed for the Europa Habitability Mission (EHM) project, a mission concept study, at the Jet Propulsion Laboratory (JPL).

Great Lakes water quality scenario models: Operational feasibility -Lake Michigan Mass Balance models

EPA Science Inventory

An overview of the Lake Michigan Mass Balance models were provided (eutrophication/nutrients, atrazine, mercury, and PCBs) with emphasis on the PCB model post-audit and forecast for Lake Trout. Provided were modeling construct, model description, and primary results. An assessm...

Evolution models of helium white dwarf-main-sequence star merger remnants: the mass distribution of single low-mass white dwarfs

NASA Astrophysics Data System (ADS)

Zhang, Xianfei; Hall, Philip D.; Jeffery, C. Simon; Bi, Shaolan

2018-02-01

It is not known how single white dwarfs with masses less than 0.5Msolar -- low-mass white dwarfs -- are formed. One way in which such a white dwarf might be formed is after the merger of a helium-core white dwarf with a main-sequence star that produces a red giant branch star and fails to ignite helium. We use a stellar-evolution code to compute models of the remnants of these mergers and find a relation between the pre-merger masses and the final white dwarf mass. Combining our results with a model population, we predict that the mass distribution of single low-mass white dwarfs formed through this channel spans the range 0.37 to 0.5Msolar and peaks between 0.45 and 0.46Msolar. Helium white dwarf--main-sequence star mergers can also lead to the formation of single helium white dwarfs with masses up to 0.51Msolar. In our model the Galactic formation rate of single low-mass white dwarfs through this channel is about 8.7X10^-3yr^-1. Comparing our models with observations, we find that the majority of single low-mass white dwarfs (<0.5Msolar) are formed from helium white dwarf--main-sequence star mergers, at a rate which is about $2$ per cent of the total white dwarf formation rate.

What Are Error Rates for Classifying Teacher and School Performance Using Value-Added Models?

ERIC Educational Resources Information Center

Schochet, Peter Z.; Chiang, Hanley S.

2013-01-01

This article addresses likely error rates for measuring teacher and school performance in the upper elementary grades using value-added models applied to student test score gain data. Using a realistic performance measurement system scheme based on hypothesis testing, the authors develop error rate formulas based on ordinary least squares and…

Scale invariance of the η-deformed AdS5 × S5 superstring, T-duality and modified type II equations

NASA Astrophysics Data System (ADS)

Arutyunov, G.; Frolov, S.; Hoare, B.; Roiban, R.; Tseytlin, A. A.

2016-02-01

We consider the ABF background underlying the η-deformed AdS5 ×S5 sigma model. This background fails to satisfy the standard IIB supergravity equations which indicates that the corresponding sigma model is not Weyl invariant, i.e. does not define a critical string theory in the usual sense. We argue that the ABF background should still define a UV finite theory on a flat 2d world-sheet implying that the η-deformed model is scale invariant. This property follows from the formal relation via T-duality between the η-deformed model and the one defined by an exact type IIB supergravity solution that has 6 isometries albeit broken by a linear dilaton. We find that the ABF background satisfies candidate type IIB scale invariance conditions which for the R-R field strengths are of the second order in derivatives. Surprisingly, we also find that the ABF background obeys an interesting modification of the standard IIB supergravity equations that are first order in derivatives of R-R fields. These modified equations explicitly depend on Killing vectors of the ABF background and, although not universal, they imply the universal scale invariance conditions. Moreover, we show that it is precisely the non-isometric dilaton of the T-dual solution that leads, after T-duality, to modification of type II equations from their standard form. We conjecture that the modified equations should follow from κ-symmetry of the η-deformed model. All our observations apply also to η-deformations of AdS3 ×S3 ×T4and AdS2 ×S2 ×T6models.

Scale invariance of the η-deformed AdS 5 × S 5 superstring, T-duality and modified type II equations

DOE PAGES

Arutyunov, G.; Frolov, S.; Hoare, B.; ...

2015-12-23

We consider the ABF background underlying the η-deformed AdS 5 × S 5 sigma model. This background fails to satisfy the standard IIB supergravity equations which indicates that the corresponding sigma model is not Weyl invariant, i.e. does not define a critical string theory in the usual sense. We argue that the ABF background should still define a UV finite theory on a flat 2d world-sheet implying that the η-deformed model is scale invariant. This property follows from the formal relation via T-duality between the η-deformed model and the one defined by an exact type IIB supergravity solution that hasmore » 6 isometries albeit broken by a linear dilaton. We find that the ABF background satisfies candidate type IIB scale invariance conditions which for the R–R field strengths are of the second order in derivatives. Surprisingly, we also find that the ABF background obeys an interesting modification of the standard IIB supergravity equations that are first order in derivatives of R–R fields. These modified equations explicitly depend on Killing vectors of the ABF background and, although not universal, they imply the universal scale invariance conditions. Moreover, we show that it is precisely the non-isometric dilaton of the T-dual solution that leads, after T-duality, to modification of type II equations from their standard form. We conjecture that the modified equations should follow from κ-symmetry of the η-deformed model. All our observations apply also to η-deformations of AdS 3 × S 3 × T 4 and AdS 2 × S 2 × T 6 models.« less

A Robust Deep Model for Improved Classification of AD/MCI Patients

PubMed Central

Li, Feng; Tran, Loc; Thung, Kim-Han; Ji, Shuiwang; Shen, Dinggang; Li, Jiang

2015-01-01

Accurate classification of Alzheimer’s Disease (AD) and its prodromal stage, Mild Cognitive Impairment (MCI), plays a critical role in possibly preventing progression of memory impairment and improving quality of life for AD patients. Among many research tasks, it is of particular interest to identify noninvasive imaging biomarkers for AD diagnosis. In this paper, we present a robust deep learning system to identify different progression stages of AD patients based on MRI and PET scans. We utilized the dropout technique to improve classical deep learning by preventing its weight co-adaptation, which is a typical cause of over-fitting in deep learning. In addition, we incorporated stability selection, an adaptive learning factor, and a multi-task learning strategy into the deep learning framework. We applied the proposed method to the ADNI data set and conducted experiments for AD and MCI conversion diagnosis. Experimental results showed that the dropout technique is very effective in AD diagnosis, improving the classification accuracies by 5.9% on average as compared to the classical deep learning methods. PMID:25955998

SAO/NASA ADS at SAO: ADS Browse Service

Science.gov Websites

Sign on [SAO/NASA ADS] ADS Browse Service ADS Home | HELP | Sitemap ADS Services Search Browse myADS Mirrors Feedback FAQ What's new Site Map Help Other NASA Centers CXC HEASARC IRSA MAST NED NSSDC -Smithsonian Center for Astrophysics [ Smithsonian logo ] The NASA Astrophysics Data System provides different

Optimizing tuning masses for helicopter rotor blade vibration reduction including computed airloads and comparison with test data

NASA Technical Reports Server (NTRS)

Pritchard, Jocelyn I.; Adelman, Howard M.; Walsh, Joanne L.; Wilbur, Matthew L.

1992-01-01

The development and validation of an optimization procedure to systematically place tuning masses along a rotor blade span to minimize vibratory loads are described. The masses and their corresponding locations are the design variables that are manipulated to reduce the harmonics of hub shear for a four-bladed rotor system without adding a large mass penalty. The procedure incorporates a comprehensive helicopter analysis to calculate the airloads. Predicting changes in airloads due to changes in design variables is an important feature of this research. The procedure was applied to a one-sixth, Mach-scaled rotor blade model to place three masses and then again to place six masses. In both cases the added mass was able to achieve significant reductions in the hub shear. In addition, the procedure was applied to place a single mass of fixed value on a blade model to reduce the hub shear for three flight conditions. The analytical results were compared to experimental data from a wind tunnel test performed in the Langley Transonic Dynamics Tunnel. The correlation of the mass location was good and the trend of the mass location with respect to flight speed was predicted fairly well. However, it was noted that the analysis was not entirely successful at predicting the absolute magnitudes of the fixed system loads.

Ad Hoc modeling, expert problem solving, and R&T program evaluation

NASA Technical Reports Server (NTRS)

Silverman, B. G.; Liebowitz, J.; Moustakis, V. S.

1983-01-01

A simplified cost and time (SCAT) analysis program utilizing personal-computer technology is presented and demonstrated in the case of the NASA-Goddard end-to-end data system. The difficulties encountered in implementing complex program-selection and evaluation models in the research and technology field are outlined. The prototype SCAT system described here is designed to allow user-friendly ad hoc modeling in real time and at low cost. A worksheet constructed on the computer screen displays the critical parameters and shows how each is affected when one is altered experimentally. In the NASA case, satellite data-output and control requirements, ground-facility data-handling capabilities, and project priorities are intricately interrelated. Scenario studies of the effects of spacecraft phaseout or new spacecraft on throughput and delay parameters are shown. The use of a network of personal computers for higher-level coordination of decision-making processes is suggested, as a complement or alternative to complex large-scale modeling.

Consumption of Added Sugars and Cardiometabolic Risk Indicators Among US Adolescents

PubMed Central

Welsh, Jean A.; Sharma, Andrea; Argeseanu, Solveig; Vos, Miriam B.

2014-01-01

Background Increased carbohydrate and sugar consumption has been associated with dyslipidemia among adults. However, the effect of high consumption of added sugars (caloric sweeteners) on measures of cardiometabolic risk among US adolescents is unknown. Methods and Results This was a cross-sectional study of 2,252 US adolescents (13–18 y) in the National Health and Nutrition Examination Survey (NHANES) 1999–2004. Dietary data from one 24-hour recall were merged with added sugar content data from the USDA MyPyramid Equivalents Databases. Multivariate-adjusted means of cardiometabolic indicators were estimated by added sugar consumption level (<10%, 10– <15%, 15– <20%, 20– <25%, 25– <30%, and ≥30% total energy) and weighted to be representative of US adolescents. Mean consumption of added sugars was 21.4% of daily energy intake. Adjusted mean high-density lipoprotein cholesterol (HDL) levels were lower, 1.38 mmol/L (95% CI: 1.32, 1.43) among the lowest consumers to 1.28 mmol/L (95% confidence interval [CI]: 1.23, 1.33) among the highest (p-trend=0.007). Geometric mean triglyceride levels ranged from 0.79 mmol/L (95% CI: 0.72, 0.86) to 0.89 mmol/L (95% CI: 0.83, 0.96) (p-trend=0.03) with greater consumption of added sugars. Among those overweight/obese (≥85th percentile body-mass-index [BMI]), HOMA-IRs were positively associated with added sugars (p-linear trend<0.001), averaging 78% higher among the highest vs. the lowest consumers (p<0.001). No significant trends were seen with low-density lipoproteins, body-mass-index, or blood pressure. Conclusion In US adolescents, consumption of added sugars is positively associated with measures of cardiometabolic risk. Long-term studies are needed to determine if reduction in added sugars will improve these parameters and, thereby decrease future cardiovascular events. PMID:21220734

Disambiguating seesaw models using invariant mass variables at hadron colliders

DOE PAGES

Dev, P. S. Bhupal; Kim, Doojin; Mohapatra, Rabindra N.

2016-01-19

Here, we propose ways to distinguish between different mechanisms behind the collider signals of TeV-scale seesaw models for neutrino masses using kinematic endpoints of invariant mass variables. We particularly focus on two classes of such models widely discussed in literature: (i) Standard Model extended by the addition of singlet neutrinos and (ii) Left-Right Symmetric Models. Relevant scenarios involving the same "smoking-gun" collider signature of dilepton plus dijet with no missing transverse energy differ from one another by their event topology, resulting in distinctive relationships among the kinematic endpoints to be used for discerning them at hadron colliders. Furthermore, these kinematic endpoints are readily translated to the mass parameters of the on-shell particles through simple analytic expressions which can be used for measuring the masses of the new particles. We also conducted a Monte Carlo simulation with detector effects in order to test the viability of the proposed strategy in a realistic environment. Finally, we discuss the future prospects of testing these scenarios at themore » $$\\sqrt{s}$$ = 14 and 100TeV hadron colliders.« less

Disambiguating seesaw models using invariant mass variables at hadron colliders

NASA Astrophysics Data System (ADS)

Dev, P. S. Bhupal; Kim, Doojin; Mohapatra, Rabindra N.

2016-01-01

We propose ways to distinguish between different mechanisms behind the collider signals of TeV-scale seesaw models for neutrino masses using kinematic endpoints of invariant mass variables. We particularly focus on two classes of such models widely discussed in literature: (i) Standard Model extended by the addition of singlet neutrinos and (ii) Left-Right Symmetric Models. Relevant scenarios involving the same "smoking-gun" collider signature of dilepton plus dijet with no missing transverse energy differ from one another by their event topology, resulting in distinctive relationships among the kinematic endpoints to be used for discerning them at hadron colliders. These kinematic endpoints are readily translated to the mass parameters of the on-shell particles through simple analytic expressions which can be used for measuring the masses of the new particles. A Monte Carlo simulation with detector effects is conducted to test the viability of the proposed strategy in a realistic environment. Finally, we discuss the future prospects of testing these scenarios at the √{s}=14 and 100 TeV hadron colliders.

Estimating Teacher and School Effectiveness in Pittsburgh: Value-Added Modeling and Results. Final Report

ERIC Educational Resources Information Center

Lipscomb, Stephen; Gill, Brian; Booker, Kevin; Johnson, Matthew

2010-01-01

At the request of Pittsburgh Public Schools (PPS) and the Pittsburgh Federation of Teachers (PFT), Mathematica is developing value-added models (VAMs) that aim to estimate the contributions of individual teachers, teams of teachers, and schools to the achievement growth of their students. The analyses described in this report are intended as an…

Degenerate stars and gravitational collapse in AdS/CFT

NASA Astrophysics Data System (ADS)

Arsiwalla, Xerxes; de Boer, Jan; Papadodimas, Kyriakos; Verlinde, Erik

2011-01-01

We construct composite CFT operators from a large number of fermionic primary fields corresponding to states that are holographically dual to a zero temperature Fermi gas in AdS space. We identify a large N regime in which the fermions behave as free particles. In the hydrodynamic limit the Fermi gas forms a degenerate star with a radius determined by the Fermi level, and a mass and angular momentum that exactly matches the boundary calculations. Next we consider an interacting regime, and calculate the effect of the gravitational back-reaction on the radius and the mass of the star using the Tolman-Oppenheimer-Volkoff equations. Ignoring other interactions, we determine the "Chandrasekhar limit" beyond which the degenerate star (presumably) undergoes gravitational collapse towards a black hole. This is interpreted on the boundary as a high density phase transition from a cold baryonic phase to a hot deconfined phase.

Tensionless string spectra on AdS3

NASA Astrophysics Data System (ADS)

Gaberdiel, Matthias R.; Gopakumar, Rajesh

2018-05-01

The spectrum of superstrings on AdS3 × S3 × M 4 with pure NS-NS flux is analysed for the background where the radius of the AdS space takes the minimal value ( k = 1). Both for M 4 = S3 × S1 and M 4 = T 4 we show that there is a special set of physical states, coming from the bottom of the spectrally flowed continuous representations, which agree in precise detail with the single particle spectrum of a free symmetric product orbifold. For the case of AdS3 × S3 × T 4 this relies on making sense of the world-sheet theory at k = 1, for which we make a concrete proposal. We also comment on the implications of this striking result.

Broad-line Type Ic supernova SN 2014ad

NASA Astrophysics Data System (ADS)

Sahu, D. K.; Anupama, G. C.; Chakradhari, N. K.; Srivastav, S.; Tanaka, Masaomi; Maeda, Keiichi; Nomoto, Ken'ichi

2018-04-01

We present optical and ultraviolet photometry and low-resolution optical spectroscopy of the broad-line Type Ic supernova SN 2014ad in the galaxy PGC 37625 (Mrk 1309), covering the evolution of the supernova during -5 to +87 d with respect to the date of maximum in the B band. A late-phase spectrum obtained at +340 d is also presented. With an absolute V-band magnitude at peak of MV = -18.86 ± 0.23 mag, SN 2014ad is fainter than supernovae associated with gamma ray bursts (GRBs), and brighter than most of the normal and broad-line Type Ic supernovae without an associated GRB. The spectral evolution indicates that the expansion velocity of the ejecta, as measured using the Si II line, is as high as ˜33 500 km s-1 around maximum, while during the post-maximum phase it settles at ˜15 000 km s-1. The expansion velocity of SN 2014ad is higher than that of all other well-observed broad-line Type Ic supernovae except for the GRB-associated SN 2010bh. The explosion parameters, determined by applying Arnett's analytical light-curve model to the observed bolometric light-curve, indicate that it was an energetic explosion with a kinetic energy of ˜(1 ± 0.3) × 1052 erg and a total ejected mass of ˜(3.3 ± 0.8) M⊙, and that ˜0.24 M⊙ of 56Ni was synthesized in the explosion. The metallicity of the host galaxy near the supernova region is estimated to be ˜0.5 Z⊙.

Intraplacental Gene Therapy with Ad-IGF-1 Corrects Naturally Occurring Rabbit Model of Intrauterine Growth Restriction

PubMed Central

Keswani, Sundeep G.; Balaji, Swathi; Katz, Anna B.; King, Alice; Omar, Khaled; Habli, Mounira; Klanke, Charles

2015-01-01

Abstract Intrauterine growth restriction (IUGR) due to placental insufficiency is a leading cause of perinatal complications for which there is no effective prenatal therapy. We have previously demonstrated that intraplacental injection of adenovirus-mediated insulin-like growth factor-1 (Ad-IGF-1) corrects fetal weight in a murine IUGR model induced by mesenteric uterine artery branch ligation. This study investigated the effect of intraplacental Ad-IGF-1 gene therapy in a rabbit model of naturally occurring IUGR (runt) due to placental insufficiency, which is similar to the human IUGR condition with onset in the early third trimester, brain sparing, and a reduction in liver weight. Laparotomy was performed on New Zealand White rabbits on day 21 of 30 days of gestation and litters were divided into five groups: Control (first position)+phosphate-buffered saline (PBS), control+Ad-IGF-1, runt (third position)+PBS, runt+Ad-IGF-1, and runt+Ad-LacZ. The effect of IGF-1 gene therapy on fetal, placental, liver, heart, lung, and musculoskeletal weights of the growth-restricted pups was examined. Protein expression after gene transfer was seen along the maternal–fetal placenta interface (n=12) 48 hr after gene therapy. There was minimal gene transfer detected in the pups or maternal organs. At term, compared with the normally grown first-position control, the runted third-position pups demonstrated significantly lower fetal, placental, liver, lung, and musculoskeletal weights. The fetal, liver, and musculoskeletal weights were restored to normal by intraplacental Ad-IGF-1 gene therapy (p<0.01), with no change in the placental weight. Intraplacental gene therapy is a novel strategy for the treatment of IUGR caused by placental insufficiency that takes advantage of an organ that will be discarded at birth. Development of nonviral IGF-1 gene delivery using placenta-specific promoters can potentially minimize toxicity to the mother and fetus and facilitate clinical

Intraplacental gene therapy with Ad-IGF-1 corrects naturally occurring rabbit model of intrauterine growth restriction.

PubMed

Keswani, Sundeep G; Balaji, Swathi; Katz, Anna B; King, Alice; Omar, Khaled; Habli, Mounira; Klanke, Charles; Crombleholme, Timothy M

2015-03-01

Intrauterine growth restriction (IUGR) due to placental insufficiency is a leading cause of perinatal complications for which there is no effective prenatal therapy. We have previously demonstrated that intraplacental injection of adenovirus-mediated insulin-like growth factor-1 (Ad-IGF-1) corrects fetal weight in a murine IUGR model induced by mesenteric uterine artery branch ligation. This study investigated the effect of intraplacental Ad-IGF-1 gene therapy in a rabbit model of naturally occurring IUGR (runt) due to placental insufficiency, which is similar to the human IUGR condition with onset in the early third trimester, brain sparing, and a reduction in liver weight. Laparotomy was performed on New Zealand White rabbits on day 21 of 30 days of gestation and litters were divided into five groups: Control (first position)+phosphate-buffered saline (PBS), control+Ad-IGF-1, runt (third position)+PBS, runt+Ad-IGF-1, and runt+Ad-LacZ. The effect of IGF-1 gene therapy on fetal, placental, liver, heart, lung, and musculoskeletal weights of the growth-restricted pups was examined. Protein expression after gene transfer was seen along the maternal-fetal placenta interface (n=12) 48 hr after gene therapy. There was minimal gene transfer detected in the pups or maternal organs. At term, compared with the normally grown first-position control, the runted third-position pups demonstrated significantly lower fetal, placental, liver, lung, and musculoskeletal weights. The fetal, liver, and musculoskeletal weights were restored to normal by intraplacental Ad-IGF-1 gene therapy (p<0.01), with no change in the placental weight. Intraplacental gene therapy is a novel strategy for the treatment of IUGR caused by placental insufficiency that takes advantage of an organ that will be discarded at birth. Development of nonviral IGF-1 gene delivery using placenta-specific promoters can potentially minimize toxicity to the mother and fetus and facilitate clinical translation of

Signal Partitioning Algorithm for Highly Efficient Gaussian Mixture Modeling in Mass Spectrometry

PubMed Central

Polanski, Andrzej; Marczyk, Michal; Pietrowska, Monika; Widlak, Piotr; Polanska, Joanna

2015-01-01

Mixture - modeling of mass spectra is an approach with many potential applications including peak detection and quantification, smoothing, de-noising, feature extraction and spectral signal compression. However, existing algorithms do not allow for automated analyses of whole spectra. Therefore, despite highlighting potential advantages of mixture modeling of mass spectra of peptide/protein mixtures and some preliminary results presented in several papers, the mixture modeling approach was so far not developed to the stage enabling systematic comparisons with existing software packages for proteomic mass spectra analyses. In this paper we present an efficient algorithm for Gaussian mixture modeling of proteomic mass spectra of different types (e.g., MALDI-ToF profiling, MALDI-IMS). The main idea is automated partitioning of protein mass spectral signal into fragments. The obtained fragments are separately decomposed into Gaussian mixture models. The parameters of the mixture models of fragments are then aggregated to form the mixture model of the whole spectrum. We compare the elaborated algorithm to existing algorithms for peak detection and we demonstrate improvements of peak detection efficiency obtained by using Gaussian mixture modeling. We also show applications of the elaborated algorithm to real proteomic datasets of low and high resolution. PMID:26230717

A Monte Carlo Simulation Comparing the Statistical Precision of Two High-Stakes Teacher Evaluation Methods: A Value-Added Model and a Composite Measure

ERIC Educational Resources Information Center

Spencer, Bryden

2016-01-01

Value-added models are a class of growth models used in education to assign responsibility for student growth to teachers or schools. For value-added models to be used fairly, sufficient statistical precision is necessary for accurate teacher classification. Previous research indicated precision below practical limits. An alternative approach has…

Value-Added Teacher Estimates as Part of Teacher Evaluations: Exploring the Effects of Data and Model Specifications on the Stability of Teacher Value-Added Scores

ERIC Educational Resources Information Center

Kersting, Nicole B.; Chen, Mei-kuang; Stigler, James W.

2013-01-01

If teacher value-added estimates (VAEs) are to be used as indicators of individual teacher performance in teacher evaluation and accountability systems, it is important to understand how much VAEs are affected by the data and model specifications used to estimate them. In this study we explored the effects of three conditions on the stability of…

Dark matter detection in supersymmetric models with non-universal gaugino masses

NASA Astrophysics Data System (ADS)

Park, Eun-Kyung

SUSY is one of the most promising new physics ideas, and will soon be tested at high energy accelerators like the CERN LHC. Moreover SUSY provides a good candidate for cold dark matter (CDM). In this dissertation, we investigated phenomenology of SUSY models with non-universal gaugino masses (NUGM) at colliding experiments using event generators such as ISAJET and examined direct and indirect detection rates of relic neutralino CDM in the universe. The motivation of these models is that in most of mSUGRA parameter space, the relic density WZ1˜ h2 is considerably larger than the WMAP measurement, and it is well known that if non-universal gaugino masses are allowed, then qualitatively new possibilities arise that are not realized in the mSUGRA model. Our first NUGM attempt is to allow a mixed wino-bino lightest SUSY particle (LSP) by lowering SU(2) gaugino mass M2 at the weak scale from its mSUGRA value while keeping the hypercharge gaugino mass M1 fixed (Mixed Wino Dark Matter). In this model, wino-like Z˜1 with sufficiently low M2 compared to M1 enhances Z˜1Z˜ 1 → W+1W-1 annihilations to reach the WMAP measured relic density. The second attempt is study on the NUGM model with different signs of M 1 and M2 (Bino-Wino Co-Annihilation Scenario). In this case, there is little mixing, so that Z˜1 remains nearly a pure bino or a pure wino. By increasing M1 ≃ M 2, enhanced bino-wino co-annihilation can achieve the relic neutralino abundance. The final attempt of NUGM models is lowering the SU(3) gaugino mass to diminish the effect of the large top quark Yukawa coupling in the running of the higgs mass, so that the value of superpotential mu parameter gets efficiently low to give rise to mixed higgsino dark matter (Mixed Higgsino Dark Matter). Consequences of these NUGM model studies show us that relaxing universality of gaugino masses in SUSY models leads to enhanced direct and indirect dark matter detection rates and reduced mZ2˜-m Z1˜ mass gap so that the

A fast mass spring model solver for high-resolution elastic objects

NASA Astrophysics Data System (ADS)

Zheng, Mianlun; Yuan, Zhiyong; Zhu, Weixu; Zhang, Guian

2017-03-01

Real-time simulation of elastic objects is of great importance for computer graphics and virtual reality applications. The fast mass spring model solver can achieve visually realistic simulation in an efficient way. Unfortunately, this method suffers from resolution limitations and lack of mechanical realism for a surface geometry model, which greatly restricts its application. To tackle these problems, in this paper we propose a fast mass spring model solver for high-resolution elastic objects. First, we project the complex surface geometry model into a set of uniform grid cells as cages through *cages mean value coordinate method to reflect its internal structure and mechanics properties. Then, we replace the original Cholesky decomposition method in the fast mass spring model solver with a conjugate gradient method, which can make the fast mass spring model solver more efficient for detailed surface geometry models. Finally, we propose a graphics processing unit accelerated parallel algorithm for the conjugate gradient method. Experimental results show that our method can realize efficient deformation simulation of 3D elastic objects with visual reality and physical fidelity, which has a great potential for applications in computer animation.

Enforcing elemental mass and energy balances for reduced order models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ma, J.; Agarwal, K.; Sharma, P.

2012-01-01

Development of economically feasible gasification and carbon capture, utilization and storage (CCUS) technologies requires a variety of software tools to optimize the designs of not only the key devices involved (e., g., gasifier, CO{sub 2} adsorber) but also the entire power generation system. High-fidelity models such as Computational Fluid Dynamics (CFD) models are capable of accurately simulating the detailed flow dynamics, heat transfer, and chemistry inside the key devices. However, the integration of CFD models within steady-state process simulators, and subsequent optimization of the integrated system, still presents significant challenges due to the scale differences in both time and length,more » as well the high computational cost. A reduced order model (ROM) generated from a high-fidelity model can serve as a bridge between the models of different scales. While high-fidelity models are built upon the principles of mass, momentum, and energy conservations, ROMs are usually developed based on regression-type equations and hence their predictions may violate the mass and energy conservation laws. A high-fidelity model may also have the mass and energy balance problem if it is not tightly converged. Conservations of mass and energy are important when a ROM is integrated to a flowsheet for the process simulation of the entire chemical or power generation system, especially when recycle streams are connected to the modeled device. As a part of the Carbon Capture Simulation Initiative (CCSI) project supported by the U.S. Department of Energy, we developed a software framework for generating ROMs from CFD simulations and integrating them with Process Modeling Environments (PMEs) for system-wide optimization. This paper presents a method to correct the results of a high-fidelity model or a ROM such that the elemental mass and energy are conserved perfectly. Correction factors for the flow rates of individual species in the product streams are solved using a

Mass transfer model of nanoparticle-facilitated contaminant transport in saturated porous media.

PubMed

Johari, Wan Lutfi Wan; Diamessis, Peter J; Lion, Leonard W

2010-02-01

A one-dimensional model has been evaluated for transport of hydrophobic contaminants, such as polycyclic aromatic hydrocarbon (PAH) compounds, facilitated by synthetic amphiphilic polyurethane (APU) nanoparticles in porous media. APU particles synthesized from poly(ethylene glycol)-modified urethane acrylate (PMUA) precursor chains have been shown to enhance the desorption rate and mobility of phenanthrene (PHEN) in soil. A reversible process governed by attachment and detachment rates was considered to describe the PMUA binding in soil in addition to PMUA transport through advection and dispersion. Ultimately, an irreversible second-order PMUA attachment rate in which the fractional soil saturation capacity with PMUA was a rate control was found to be adequate to describe the retention of PMUA particles. A gamma-distributed site model (GS) was used to describe the spectrum of physical/chemical constraints for PHEN transfer from solid to aqueous phases. Instantaneous equilibrium was assumed for PMUA-PHEN interactions. The coupled model for PMUA and PHEN behavior successfully described the enhanced elution profile of PHEN by PMUA. Sensitivity analysis was performed to analyze the significance of model parameters on model predictions. The adjustable parameter alpha in the gamma-distribution shapes the contaminant desorption distribution profile as well as elution and breakthrough curves. Model simulations show the use of PMUA can be also expected to improve the release rate of PHEN in soils with higher organic carbon content. The percentage removal of PHEN mass over time is shown to be influenced by the concentration of PMUA added and this information can be used to optimize cost and time require to accomplish a desired remediation goal. Copyright 2009 Elsevier Ltd. All rights reserved.

AutoLens: Automated Modeling of a Strong Lens's Light, Mass and Source

NASA Astrophysics Data System (ADS)

Nightingale, J. W.; Dye, S.; Massey, Richard J.

2018-05-01

This work presents AutoLens, the first entirely automated modeling suite for the analysis of galaxy-scale strong gravitational lenses. AutoLens simultaneously models the lens galaxy's light and mass whilst reconstructing the extended source galaxy on an adaptive pixel-grid. The method's approach to source-plane discretization is amorphous, adapting its clustering and regularization to the intrinsic properties of the lensed source. The lens's light is fitted using a superposition of Sersic functions, allowing AutoLens to cleanly deblend its light from the source. Single component mass models representing the lens's total mass density profile are demonstrated, which in conjunction with light modeling can detect central images using a centrally cored profile. Decomposed mass modeling is also shown, which can fully decouple a lens's light and dark matter and determine whether the two component are geometrically aligned. The complexity of the light and mass models are automatically chosen via Bayesian model comparison. These steps form AutoLens's automated analysis pipeline, such that all results in this work are generated without any user-intervention. This is rigorously tested on a large suite of simulated images, assessing its performance on a broad range of lens profiles, source morphologies and lensing geometries. The method's performance is excellent, with accurate light, mass and source profiles inferred for data sets representative of both existing Hubble imaging and future Euclid wide-field observations.

Consumption of added sugars and indicators of cardiovascular disease risk among US adolescents.

PubMed

Welsh, Jean A; Sharma, Andrea; Cunningham, Solveig A; Vos, Miriam B

2011-01-25

Whereas increased carbohydrate and sugar consumption has been associated with higher cardiovascular disease risk among adults, little is known about the impact of high consumption of added sugars (caloric sweeteners) among US adolescents. In a cross-sectional study of 2157 US adolescents in the National Health and Nutrition Examination Survey (NHANES) 1999 to 2004, dietary data from one 24-hour recall were merged with added sugar content data from the US Department of Agriculture MyPyramid Equivalents databases. Measures of cardiovascular disease risk were estimated by added sugar consumption level (< 10%, 10 to < 15%, 15 to < 20%, 20 to < 25%, 25 to < 30%, and ≥ 30% of total energy). Multivariable means were weighted to be representative of US adolescents and variances adjusted for the complex sampling methods. Daily consumption of added sugars averaged 21.4% of total energy. Added sugars intake was inversely correlated with mean high-density lipoprotein cholesterol levels (mmol/L) which were 1.40 (95% confidence interval [CI] 1.36 to 1.44) among the lowest consumers and 1.28 (95% CI 1.23 to 1.33) among the highest (P trend = 0.001). Added sugars were positively correlated with low-density lipoproteins (P trend =0.01) and geometric mean triglycerides (P trend = 0.05). Among the lowest and highest consumers, respectively, low-density lipoproteins (mmol/L) were 2.24 (95% CI 2.12 to 2.37) and 2.44 (95% CI 2.34 to 2.53), and triglycerides (mmol/L) were 0.81 (95% CI 0.74, 0.88) and 0.89 (95% CI 0.83 to 0.96). Among those overweight/obese (≥ 85th percentile body-mass-index), added sugars were positively correlated with the homeostasis model assessment (P linear trend = 0.004). Consumption of added sugars among US adolescents is positively associated with multiple measures known to increase cardiovascular disease risk.

Measurement Error and Bias in Value-Added Models. Research Report. ETS RR-17-25

ERIC Educational Resources Information Center

Kane, Michael T.

2017-01-01

By aggregating residual gain scores (the differences between each student's current score and a predicted score based on prior performance) for a school or a teacher, value-added models (VAMs) can be used to generate estimates of school or teacher effects. It is known that random errors in the prior scores will introduce bias into predictions of…

Accounting for Co-Teaching: A Guide for Policymakers and Developers of Value-Added Models

ERIC Educational Resources Information Center

Isenberg, Eric; Walsh, Elias

2015-01-01

We outline the options available to policymakers for addressing co-teaching in a value-added model. Building on earlier work, we propose an improvement to a method of accounting for co-teaching that treats co-teachers as teams, with each teacher receiving equal credit for co-taught students. Hock and Isenberg (2012) described a method known as the…

Results of the Lake Michigan Mass Balance Project: Atrazine Modeling Report

EPA Science Inventory

This report covers an overview of chemical properties, measurements in air and water, model construct and assumptions, and results of mathematical mass balance modeling of the herbicide atrazine in the Lake Michigan basin. Within the context of the mass balance, an overview of a...

Modeling and Performance Simulation of the Mass Storage Network Environment

NASA Technical Reports Server (NTRS)

Kim, Chan M.; Sang, Janche

2000-01-01

This paper describes the application of modeling and simulation in evaluating and predicting the performance of the mass storage network environment. Network traffic is generated to mimic the realistic pattern of file transfer, electronic mail, and web browsing. The behavior and performance of the mass storage network and a typical client-server Local Area Network (LAN) are investigated by modeling and simulation. Performance characteristics in throughput and delay demonstrate the important role of modeling and simulation in network engineering and capacity planning.

Extension to Higher Mass Numbers of an Improved Knockout-Ablation-Coalescence Model for Secondary Neutron and Light Ion Production in Cosmic Ray Interactions

NASA Astrophysics Data System (ADS)

Indi Sriprisan, Sirikul; Townsend, Lawrence; Cucinotta, Francis A.; Miller, Thomas M.

Purpose: An analytical knockout-ablation-coalescence model capable of making quantitative predictions of the neutron spectra from high-energy nucleon-nucleus and nucleus-nucleus collisions is being developed for use in space radiation protection studies. The FORTRAN computer code that implements this model is called UBERNSPEC. The knockout or abrasion stage of the model is based on Glauber multiple scattering theory. The ablation part of the model uses the classical evaporation model of Weisskopf-Ewing. In earlier work, the knockout-ablation model has been extended to incorporate important coalescence effects into the formalism. Recently, alpha coalescence has been incorporated, and the ability to predict light ion spectra with the coalescence model added. The earlier versions were limited to nuclei with mass numbers less than 69. In this work, the UBERNSPEC code has been extended to make predictions of secondary neutrons and light ion production from the interactions of heavy charged particles with higher mass numbers (as large as 238). The predictions are compared with published measurements of neutron spectra and light ion energy for a variety of collision pairs. Furthermore, the predicted spectra from this work are compared with the predictions from the recently-developed heavy ion event generator incorporated in the Monte Carlo radiation transport code HETC-HEDS.

Design of Value-Added Models for IMPACT and TEAM in DC Public Schools, 2010-2011 School Year. Final Report

ERIC Educational Resources Information Center

Isenberg, Eric; Hock, Heinrich

2011-01-01

This report presents the value-added models that will be used to measure school and teacher effectiveness in the District of Columbia Public Schools (DCPS) in the 2010-2011 school year. It updates the earlier technical report, "Measuring Value Added for IMPACT and TEAM in DC Public Schools." The earlier report described the methods used…

AdS7/CFT6 with orientifolds

NASA Astrophysics Data System (ADS)

Apruzzi, Fabio; Fazzi, Marco

2018-01-01

AdS7 solutions of massive type IIA have been classified, and are dual to a large class of six-dimensional (1, 0) SCFT's whose tensor branch deformations are described by linear quivers of SU groups. Quivers and AdS vacua depend solely on the group theory data of the NS5-D6-D8 brane configurations engineering the field theories. This has allowed for a direct holographic match of their a conformal anomaly. In this paper we extend the match to cases where O6 and O8-planes are present, thereby introducing SO and USp groups in the quivers. In all of them we show that the a anomaly computed in supergravity agrees with the holographic limit of the exact field theory result, which we extract from the anomaly polynomial. As a byproduct we construct special AdS7 vacua dual to nonperturbative F-theory configurations. Finally, we propose a holographic a-theorem for six-dimensional Higgs branch RG flows.

Modeling and Understanding the Mass Balance of Himalayan Glaciers

NASA Astrophysics Data System (ADS)

Rengaraju, S.; Achutarao, K. M.

2017-12-01

Changes in glaciers are among the most visible manifestations of a changing climate. Retreating glaciers have significant impacts on global sea-level rise and stream flow of rivers. Modeling the response of glaciers to climate change is important for many reasons including predicting changes in global sea level and water resources. The mass balance of a glacier provides a robust way of ascertaining whether there has been a net loss or gain of ice from the glacier. The mass balance reflects all of the meteorological forcing of the glacier - from the accumulation of snow and the combined losses from ablation and sublimation. The glaciers in the Himalayan region are considered sensitive to climate change and their fate under climate change is critical to the billions of humans that rely on rivers originating from these glaciers. Owing to complex terrain and harsh climate, Himalayan glaciers have historically been poorly monitored and this makes it harder to understand and predict their fate.In this study we model the observed mass balance of Himalayan glaciers using the methods of Radic and Hock (2011) and analyze the response to future changes in climate based on the model projections from the Coupled Model Intercomparison Project Phase-5 (CMIP5; Taylor et al., 2012). We make use of available observations of mass balance from various sources for 14 glaciers across the Himalayas. These glaciers are located across distinct climatic conditions - from the Karakoram and Hindu Kush in the West that are fed by winter precipitation caused by westerly disturbances to the Eastern Himalayas where the summer monsoon provides the bulk of the precipitation. For the historical observed period, we use the ECMWF Re-Analysis (ERA-40) for temperature and VASClimO (GPCC) data at 2.5°x2.5° resolution to calibrate the mass balance model. We evaluate the CMIP5 model simulations for their fidelity in capturing the distinct climatic conditions across the Himalayas in order to select

Accuracy Assessment of Digital Surface Models Based on WorldView-2 and ADS80 Stereo Remote Sensing Data

PubMed Central

Hobi, Martina L.; Ginzler, Christian

2012-01-01

Digital surface models (DSMs) are widely used in forest science to model the forest canopy. Stereo pairs of very high resolution satellite and digital aerial images are relatively new and their absolute accuracy for DSM generation is largely unknown. For an assessment of these input data two DSMs based on a WorldView-2 stereo pair and a ADS80 DSM were generated with photogrammetric instruments. Rational polynomial coefficients (RPCs) are defining the orientation of the WorldView-2 satellite images, which can be enhanced with ground control points (GCPs). Thus two WorldView-2 DSMs were distinguished: a WorldView-2 RPCs-only DSM and a WorldView-2 GCP-enhanced RPCs DSM. The accuracy of the three DSMs was estimated with GPS measurements, manual stereo-measurements, and airborne laser scanning data (ALS). With GCP-enhanced RPCs the WorldView-2 image orientation could be optimised to a root mean square error (RMSE) of 0.56 m in planimetry and 0.32 m in height. This improvement in orientation allowed for a vertical median error of −0.24 m for the WorldView-2 GCP-enhanced RPCs DSM in flat terrain. Overall, the DSM based on ADS80 images showed the highest accuracy of the three models with a median error of 0.08 m over bare ground. As the accuracy of a DSM varies with land cover three classes were distinguished: herb and grass, forests, and artificial areas. The study suggested the ADS80 DSM to best model actual surface height in all three land cover classes, with median errors <1.1 m. The WorldView-2 GCP-enhanced RPCs model achieved good accuracy, too, with median errors of −0.43 m for the herb and grass vegetation and −0.26 m for artificial areas. Forested areas emerged as the most difficult land cover type for height modelling; still, with median errors of −1.85 m for the WorldView-2 GCP-enhanced RPCs model and −1.12 m for the ADS80 model, the input data sets evaluated here are quite promising for forest canopy modelling. PMID:22778645

Accuracy assessment of digital surface models based on WorldView-2 and ADS80 stereo remote sensing data.

PubMed

Hobi, Martina L; Ginzler, Christian

2012-01-01

Digital surface models (DSMs) are widely used in forest science to model the forest canopy. Stereo pairs of very high resolution satellite and digital aerial images are relatively new and their absolute accuracy for DSM generation is largely unknown. For an assessment of these input data two DSMs based on a WorldView-2 stereo pair and a ADS80 DSM were generated with photogrammetric instruments. Rational polynomial coefficients (RPCs) are defining the orientation of the WorldView-2 satellite images, which can be enhanced with ground control points (GCPs). Thus two WorldView-2 DSMs were distinguished: a WorldView-2 RPCs-only DSM and a WorldView-2 GCP-enhanced RPCs DSM. The accuracy of the three DSMs was estimated with GPS measurements, manual stereo-measurements, and airborne laser scanning data (ALS). With GCP-enhanced RPCs the WorldView-2 image orientation could be optimised to a root mean square error (RMSE) of 0.56 m in planimetry and 0.32 m in height. This improvement in orientation allowed for a vertical median error of -0.24 m for the WorldView-2 GCP-enhanced RPCs DSM in flat terrain. Overall, the DSM based on ADS80 images showed the highest accuracy of the three models with a median error of 0.08 m over bare ground. As the accuracy of a DSM varies with land cover three classes were distinguished: herb and grass, forests, and artificial areas. The study suggested the ADS80 DSM to best model actual surface height in all three land cover classes, with median errors <1.1 m. The WorldView-2 GCP-enhanced RPCs model achieved good accuracy, too, with median errors of -0.43 m for the herb and grass vegetation and -0.26 m for artificial areas. Forested areas emerged as the most difficult land cover type for height modelling; still, with median errors of -1.85 m for the WorldView-2 GCP-enhanced RPCs model and -1.12 m for the ADS80 model, the input data sets evaluated here are quite promising for forest canopy modelling.

Improving the XAJ Model on the Basis of Mass-Energy Balance

NASA Astrophysics Data System (ADS)

Fang, Yuanhao; Corbari, Chiara; Zhang, Xingnan; Mancini, Marco

2014-11-01

Introduction: The Xin'anjiang(XAJ) model is a conceptual model developed by the group led by Prof. Ren-Jun Zhao, which takes the pan evaporation as one of its input and then computes the effective evapotranspiration (ET) of the catchment by mass balance. Such scheme can ensure a good performance of discharge simulation but has obvious defects, one of which is that the effective ET is spatially-constant over the computation unit, neglecting the spatial variation of variables that influence the effective ET and therefore the simulation of ET and SM by the XAJ model, comparing with discharge, is less reliable. In this study, The XAJ model was improved to employ both energy and mass balance to compute the ET following the energy-mass balance scheme of FEST-EWB. model.

Improving the XAJ Model on the Basis of Mass-Energy Balance

NASA Astrophysics Data System (ADS)

Fang, Yuanghao; Corbari, Chiara; Zhang, Xingnan; Mancini, Marco

2014-11-01

The Xin’anjiang(XAJ) model is a conceptual model developed by the group led by Prof. Ren-Jun Zhao, which takes the pan evaporation as one of its input and then computes the effective evapotranspiration (ET) of the catchment by mass balance. Such scheme can ensure a good performance of discharge simulation but has obvious defects, one of which is that the effective ET is spatially-constant over the computation unit, neglecting the spatial variation of variables that influence the effective ET and therefore the simulation of ET and SM by the XAJ model, comparing with discharge, is less reliable. In this study, The XAJ model was improved to employ both energy and mass balance to compute the ET following the energy-mass balance scheme of FEST-EWB. model.

Marine and terrestrial factors affecting Adélie penguin Pygoscelis adeliae chick growth and recruitment off the western Antarctic Peninsula

USGS Publications Warehouse

Chapman, Erik W.; Hofmann, Eileen E.; Patterson, Donna L.; Ribic, Christine A.; Fraser, William R.

2011-01-01

An individual-based bioenergetics model that simulates the growth of an Adélie penguin Pygoscelis adeliaechick from hatching to fledging was used to assess marine and terrestrial factors that affect chick growth and fledging mass off the western Antarctic Peninsula. Simulations considered the effects on Adélie penguin fledging mass of (1) modification of chick diet through the addition of Antarctic silverfish Pleuragramma antarcticum to an all-Antarctic krillEuphausia superba diet, (2) reduction of provisioning rate which may occur as a result of an environmental stress such as reduced prey availability, and (3) increased thermoregulatory costs due to wetting of chicks which may result from increased precipitation or snow-melt in colonies. Addition of 17% Antarctic silverfish of Age-Class 3 yr (AC3) to a penguin chick diet composed of Antarctic krill increased chick fledging mass by 5%. Environmental stress that results in >4% reduction in provisioning rate or wetting of just 10% of the chick’s surface area decreased fledging mass enough to reduce the chick’s probability of successful recruitment. The negative effects of reduced provisioning and wetting on chick growth can be compensated for by inclusion of Antarctic silverfish of AC3 and older in the chick diet. Results provide insight into climate-driven processes that influence chick growth and highlight a need for field research designed to investigate factors that determine the availability of AC3 and older Antarctic silverfish to foraging Adélie penguins and the influence of snowfall on chick wetting, thermoregulation and adult provisioning rate.

Modeling the influence of coupled mass transfer processes on mass flux downgradient of heterogeneous DNAPL source zones

NASA Astrophysics Data System (ADS)

Yang, Lurong; Wang, Xinyu; Mendoza-Sanchez, Itza; Abriola, Linda M.

2018-04-01

Sequestered mass in low permeability zones has been increasingly recognized as an important source of organic chemical contamination that acts to sustain downgradient plume concentrations above regulated levels. However, few modeling studies have investigated the influence of this sequestered mass and associated (coupled) mass transfer processes on plume persistence in complex dense nonaqueous phase liquid (DNAPL) source zones. This paper employs a multiphase flow and transport simulator (a modified version of the modular transport simulator MT3DMS) to explore the two- and three-dimensional evolution of source zone mass distribution and near-source plume persistence for two ensembles of highly heterogeneous DNAPL source zone realizations. Simulations reveal the strong influence of subsurface heterogeneity on the complexity of DNAPL and sequestered (immobile/sorbed) mass distribution. Small zones of entrapped DNAPL are shown to serve as a persistent source of low concentration plumes, difficult to distinguish from other (sorbed and immobile dissolved) sequestered mass sources. Results suggest that the presence of DNAPL tends to control plume longevity in the near-source area; for the examined scenarios, a substantial fraction (43.3-99.2%) of plume life was sustained by DNAPL dissolution processes. The presence of sorptive media and the extent of sorption non-ideality are shown to greatly affect predictions of near-source plume persistence following DNAPL depletion, with plume persistence varying one to two orders of magnitude with the selected sorption model. Results demonstrate the importance of sorption-controlled back diffusion from low permeability zones and reveal the importance of selecting the appropriate sorption model for accurate prediction of plume longevity. Large discrepancies for both DNAPL depletion time and plume longevity were observed between 2-D and 3-D model simulations. Differences between 2- and 3-D predictions increased in the presence of

Investigating Added Value of Regional Climate Modeling in North American Winter Storm Track Simulations

NASA Astrophysics Data System (ADS)

Poan, E.; Gachon, P., Sr.; Laprise, R.; Aider, R.; Dueymes, G.

2017-12-01

This study describes a framework using possibilities given by regional climate models (RCMs) to gain insight into extratropical cyclone (EC) activity during winter over North America (NA). Recent past climate period (1981 - 2005) is firstly considered using the NCEP regional reanalysis (NARR) as a reference, along with the European global reanalysis ERA-Interim (ERAI) and two CMIP5 Global Climate Models (GCMs) used to drive the Canadian RCM - version 5 (CRCM5) and the corresponding regional-scale simulations. While ERAI and GCM simulations show basic agreement with NARR in terms of climatological EC track patterns, detailed bias analyses show that, on the one hand, ERAI presents statistically significant positive biases in terms of EC genesis and therefore occurrence while their intensity is well captured. On the other hand, GCMs present large negative intensity biases in the overall NA domain and particularly over the eastern coast. In addition, storm occurrence from GCMs over the northwestern topographic regions is highly overestimated. When the CRCM5 is driven by ERAI, no significant skill deterioration arises and, more importantly, all storm characteristics near areas with main relief and over regions with large water masses are significantly improved with respect to ERAI. Conversely, in GCM-driven simulations, the added value from the CRCM5 is less prominent and systematic, except over western areas with high topography and over the Western Atlantic coastlines where the most frequent and intense ECs are located. Finally, time period near the end of the 21st century (2071-2100) is considered to analyze EC characteristic trends and changes relative to the current climate conditions, showing important modifications in storm activity for certain winter months, especially in term of intensity over the eastern coast.

Two Virasoro symmetries in stringy warped AdS 3

DOE PAGES

Compere, Geoffrey; Guica, Monica; Rodriguez, Maria J.

2014-12-02

We study three-dimensional consistent truncations of type IIB supergravity which admit warped AdS 3 solutions. These theories contain subsectors that have no bulk dynamics. We show that the symplectic form for these theories, when restricted to the non-dynamical subsectors, equals the symplectic form for pure Einstein gravity in AdS 3. Consequently, for each consistent choice of boundary conditions in AdS 3, we can define a consistent phase space in warped AdS 3 with identical conserved charges. This way, we easily obtain a Virasoro × Virasoro asymptotic symmetry algebra in warped AdS 3; two different types of Virasoro × Kač-Moody symmetriesmore » are also consistent alternatives. Next, we study the phase space of these theories when propagating modes are included. We show that, as long as one can define a conserved symplectic form without introducing instabilities, the Virasoro × Virasoro asymptotic symmetries can be extended to the entire (linearised) phase space. In conclusion, this implies that, at least at semi-classical level, consistent theories of gravity in warped AdS 3 are described by a two-dimensional conformal field theory, as long as stability is not an issue.« less

Two Virasoro symmetries in stringy warped AdS 3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Compere, Geoffrey; Guica, Monica; Rodriguez, Maria J.

We study three-dimensional consistent truncations of type IIB supergravity which admit warped AdS 3 solutions. These theories contain subsectors that have no bulk dynamics. We show that the symplectic form for these theories, when restricted to the non-dynamical subsectors, equals the symplectic form for pure Einstein gravity in AdS 3. Consequently, for each consistent choice of boundary conditions in AdS 3, we can define a consistent phase space in warped AdS 3 with identical conserved charges. This way, we easily obtain a Virasoro × Virasoro asymptotic symmetry algebra in warped AdS 3; two different types of Virasoro × Kač-Moody symmetriesmore » are also consistent alternatives. Next, we study the phase space of these theories when propagating modes are included. We show that, as long as one can define a conserved symplectic form without introducing instabilities, the Virasoro × Virasoro asymptotic symmetries can be extended to the entire (linearised) phase space. In conclusion, this implies that, at least at semi-classical level, consistent theories of gravity in warped AdS 3 are described by a two-dimensional conformal field theory, as long as stability is not an issue.« less

A Novel Triggerless Approach for Modeling Mass Wasting Susceptibility

NASA Astrophysics Data System (ADS)

Aly, M. H.; Rowden, K. W.

2017-12-01

Common approaches for modeling mass wasting susceptibility rely on using triggers, which are catalysts for failure, as critical inputs. Frequently used triggers include removal of the toe of a slope or vegetation and time correlated events such as seismicity or heavy precipitation. When temporal data are unavailable, correlating triggers with a particular mass wasting event (MWE) is futile. Meanwhile, geologic structures directly influence slope stability and are typically avoided in alternative modeling approaches. Depending on strata's dip direction, underlying geology can make a slope either stronger or weaker. To heuristically understand susceptibility and reliably infer risk, without being constrained by the previously mentioned limitations, a novel triggerless approach is conceived in this study. Core requisites include a digital elevation model and digitized geologic maps containing geologic formations delineated as polygons encompassing adequate distribution of structural attitudes. Tolerably simple geology composed of gently deformed, relatively flat-lying Carboniferous strata with minimal faulting or monoclines, ideal for applying this new triggerless approach, is found in the Boston Mountains, NW Arkansas, where 47 MWEs are documented. Two models are then created; one model has integrated Empirical Bayesian Kriging (EBK) and fuzzy logic, while the second model has employed a standard implementation of a weighted overlay. Statistical comparisons show that the first model has identified 83%, compared to only 28% for the latter model, of the failure events in categories ranging from moderate to very high susceptibility. These results demonstrate that the introduced triggerless approach is efficiently capable of modeling mass wasting susceptibility, by incorporating EBK and fuzzy logic, in areas lacking temporal datasets.

Phases of global AdS black holes

NASA Astrophysics Data System (ADS)

Basu, Pallab; Krishnan, Chethan; Subramanian, P. N. Bala

2016-06-01

We study the phases of gravity coupled to a charged scalar and gauge field in an asymptotically Anti-de Sitter spacetime ( AdS 4) in the grand canonical ensemble. For the conformally coupled scalar, an intricate phase diagram is charted out between the four relevant solutions: global AdS, boson star, Reissner-Nordstrom black hole and the hairy black hole. The nature of the phase diagram undergoes qualitative changes as the charge of the scalar is changed, which we discuss. We also discuss the new features that arise in the extremal limit.

Effects of independently altering body weight and body mass on the metabolic cost of running.

PubMed

Teunissen, Lennart P J; Grabowski, Alena; Kram, Rodger

2007-12-01

The metabolic cost of running is substantial, despite the savings from elastic energy storage and return. Previous studies suggest that generating vertical force to support body weight and horizontal forces to brake and propel body mass are the major determinants of the metabolic cost of running. In the present study, we investigated how independently altering body weight and body mass affects the metabolic cost of running. Based on previous studies, we hypothesized that reducing body weight would decrease metabolic rate proportionally, and adding mass and weight would increase metabolic rate proportionally. Further, because previous studies show that adding mass alone does not affect the forces generated on the ground, we hypothesized that adding mass alone would have no substantial effect on metabolic rate. We manipulated the body weight and body mass of 10 recreational human runners and measured their metabolic rates while they ran at 3 m s(-1). We reduced weight using a harness system, increased mass and weight using lead worn about the waist, and increased mass alone using a combination of weight support and added load. We found that net metabolic rate decreased in less than direct proportion to reduced body weight, increased in slightly more than direct proportion to added load (added mass and weight), and was not substantially different from normal running with added mass alone. Adding mass alone was not an effective method for determining the metabolic cost attributable to braking/propelling body mass. Runners loaded with mass alone did not generate greater vertical or horizontal impulses and their metabolic costs did not substantially differ from those of normal running. Our results show that generating force to support body weight is the primary determinant of the metabolic cost of running. Extrapolating our reduced weight data to zero weight suggests that supporting body weight comprises at most 74% of the net cost of running. However, 74% is probably an

An open-source library for the numerical modeling of mass-transfer in solid oxide fuel cells

NASA Astrophysics Data System (ADS)

Novaresio, Valerio; García-Camprubí, María; Izquierdo, Salvador; Asinari, Pietro; Fueyo, Norberto

2012-01-01

the simulation of the steady state mass and momentum transport in a multi-species gas mixture, possibly in a porous medium. The software is particularly designed to be used as the mass-transport library for the modeling of solid oxide fuel cells (SOFC). When supplemented with other sub-models, such as thermal and charge-transport ones, it allows the prediction of the cell polarization curve and hence the cell performance. Solution method: Standard finite volume method (FVM) is used for solving all the conservation equations. The pressure-velocity coupling is solved using the SIMPLE algorithm (possibly adding a porous drag term if required). The mass transport can be calculated using different alternative models, namely Fick, Maxwell-Stefan or dusty gas model. The code adopts a segregated method to solve the resulting linear system of equations. The different regions of the SOFC, namely gas channels, electrodes and electrolyte, are solved independently, and coupled through boundary conditions. Restrictions: When extremely large species fluxes are considered, current implementation of the Neumann and Robin boundary conditions do not avoid negative values of molar and/or mass fractions, which finally end up with numerical instability. However this never happened in the documented runs. Eventually these boundary conditions could be reformulated to become more robust. Running time: From seconds to hours depending on the mesh size and number of species. For example, on a 64 bit machine with Intel Core Duo T8300 and 3 GBytes of RAM, the provided test run requires less than 1 second.

What is the truth? An application of the Extended Parallel Process Model to televised truth® ads.

PubMed

Lavoie, Nicole R; Quick, Brian L

2013-01-01

The purpose of this study was to analyze television ads in the truth® campaign using the Extended Parallel Process Model (EPPM) as a framework. Among the ads (n = 86) analyzed, results revealed a heavy reliance on severity messages, modest attention to susceptibility messages, and no inclusion of recommended response messages in the form of self-efficacy and response efficacy. The reliance on emphasizing the health threat, without incorporating recommended response messages, is discussed with respect to the likelihood of galvanizing maladaptive responses such as psychological reactance, denial, and defensive avoidance resulting from exposure to these ads. Additionally, the unintended outcomes for secondary audiences including but not limited to stigma are considered. Implications and suggestions for practitioners and theorists are explored.

New massive gravity and AdS(4) counterterms.

PubMed

Jatkar, Dileep P; Sinha, Aninda

2011-04-29

We show that the recently proposed Dirac-Born-Infeld extension of new massive gravity emerges naturally as a counterterm in four-dimensional anti-de Sitter space (AdS(4)). The resulting on-shell Euclidean action is independent of the cutoff at zero temperature. We also find that the same choice of counterterm gives the usual area law for the AdS(4) Schwarzschild black hole entropy in a cutoff-independent manner. The parameter values of the resulting counterterm action correspond to a c=0 theory in the context of the duality between AdS(3) gravity and two-dimensional conformal field theory. We rewrite this theory in terms of the gauge field that is used to recast 3D gravity as a Chern-Simons theory.

The evolution of massive stars including mass loss - Presupernova models and explosion

NASA Technical Reports Server (NTRS)

Woosley, S. E.; Langer, Norbert; Weaver, Thomas A.

1993-01-01

The evolution of massive stars of 35, 40, 60, and 85 solar masses is followed through all stages of nuclear burning to the point of Fe core collapse. Critical nuclear reaction and mass-loss rates are varied. Efficient mass loss during the Wolf-Rayet (WR) stage is likely to lead to final masses as small as 4 solar masses. For a reasonable parameterization of the mass loss, there may be convergence of all WR stars, both single and in binaries, to a narrow band of small final masses. Our representative model, a 4.25 solar-mass WR presupernova derived from a 60 solar mass star, is followed through a simulated explosion, and its explosive nucleosynthesis and light curve are determined. Its properties are similar to those observed in Type Ib supernovae. The effects of the initial mass and mass loss on the presupernova structure of small mass WR models is also explored. Important properties of the presupernova star and its explosion can only be obtained by following the complete evolution starting on the main sequence.

Floquet scalar dynamics in global AdS

NASA Astrophysics Data System (ADS)

Biasi, Anxo; Carracedo, Pablo; Mas, Javier; Musso, Daniele; Serantes, Alexandre

2018-04-01

We study periodically driven scalar fields and the resulting geometries with global AdS asymptotics. These solutions describe the strongly coupled dynamics of dual finite-size quantum systems under a periodic driving which we interpret as Floquet condensates. They span a continuous two-parameter space that extends the linearized solutions on AdS. We map the regions of stability in the solution space. In a significant portion of the unstable subspace, two very different endpoints are reached depending upon the sign of the perturbation. Collapse into a black hole occurs for one sign. For the opposite sign instead one attains a regular solution with periodic modulation. We also construct quenches where the driving frequency and amplitude are continuously varied. Quasistatic quenches can interpolate between pure AdS and sourced solutions with time periodic vev. By suitably choosing the quasistatic path one can obtain boson stars dual to Floquet condensates at zero driving field. We characterize the adiabaticity of the quenching processes. Besides, we speculate on the possible connections of this framework with time crystals.

Brain mass estimation by head circumference and body mass methods in neonatal glycaemic modelling and control.

PubMed

Gunn, Cameron Allan; Dickson, Jennifer L; Pretty, Christopher G; Alsweiler, Jane M; Lynn, Adrienne; Shaw, Geoffrey M; Chase, J Geoffrey

2014-07-01

Hyperglycaemia is a common complication of stress and prematurity in extremely low-birth-weight infants. Model-based insulin therapy protocols have the ability to safely improve glycaemic control for this group. Estimating non-insulin-mediated brain glucose uptake by the central nervous system in these models is typically done using population-based body weight models, which may not be ideal. A head circumference-based model that separately treats small-for-gestational-age (SGA) and appropriate-for-gestational-age (AGA) infants is compared to a body weight model in a retrospective analysis of 48 patients with a median birth weight of 750g and median gestational age of 25 weeks. Estimated brain mass, model-based insulin sensitivity (SI) profiles, and projected glycaemic control outcomes are investigated. SGA infants (5) are also analyzed as a separate cohort. Across the entire cohort, estimated brain mass deviated by a median 10% between models, with a per-patient median difference in SI of 3.5%. For the SGA group, brain mass deviation was 42%, and per-patient SI deviation 13.7%. In virtual trials, 87-93% of recommended insulin rates were equal or slightly reduced (Δ<0.16mU/h) under the head circumference method, while glycaemic control outcomes showed little change. The results suggest that body weight methods are not as accurate as head circumference methods. Head circumference-based estimates may offer improved modelling accuracy and a small reduction in insulin administration, particularly for SGA infants. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Mass-balance modelling of Ak-Shyirak massif Glaciers, Inner Tian Shan

NASA Astrophysics Data System (ADS)

Rets, Ekaterina; Barandun, Martina; Belozerov, Egor; Petrakov, Dmitry; Shpuntova, Alena

2017-04-01

Tian Shan is a water tower of Central Asia. Rapid and accelerating glacier downwasting is typical for this region. Study sites - Sary-Tor glacier and Glacier No.354 are located in Ak-Shyirak massif, Naryn headwaters. Sary-Tor was chosen as representative for Ak-Shyirak (Ushnurtsev, 1991; Oledeneniye TianShanya, 1995) for direct mass-balance measurements in 1985-1991. Glacier No.354 was an object of direct mass-balance measurements for 2011-2016. An energy-balance distributed A-Melt model (Rets et al, 2010) was used to reconstruct mass-balance for the glaciers for 2003-2015. Verification of modelingresults showed a good reproduction of direct melting measurements data on ablation stakes and mass loss according to geodetic method. Modeling results for Glacier No. 354 were compared to different modeling approach: distributed accumulation and temperature-index melt (Kronenberg et al, 2016)

Antismoking Ads at the Point of Sale: The Influence of Ad Type and Context on Ad Reactions.

PubMed

Kim, Annice; Nonnemaker, James; Guillory, Jamie; Shafer, Paul; Parvanta, Sarah; Holloway, John; Farrelly, Matthew

2017-06-01

Efforts are underway to educate consumers about the dangers of smoking at the point of sale (POS). Research is limited about the efficacy of POS antismoking ads to guide campaign development. This study experimentally tests whether the type of antismoking ad and the context in which ads are viewed influence people's reactions to the ads. A national convenience sample of 7,812 adult current smokers and recent quitters was randomized to 1 of 39 conditions. Participants viewed one of the four types of antismoking ads (negative health consequences-graphic, negative social consequences-intended emotive, benefits of quitting-informational, benefits of quitting-graphic) in one of the three contexts (alone, next to a cigarette ad, POS tobacco display). We assessed participants' reactions to the ads, including perceived effectiveness, negative emotion, affective dissonance, and motivational reaction. Graphic ads elicited more negative emotion and affective dissonance than benefits of quitting ads. Graphic ads elicited higher perceived effectiveness and more affective dissonance than intended emotive ads. Antismoking ads fared best when viewed alone, and graphic ads were least influenced by the context in which they were viewed. These results suggest that in developing POS campaigns, it is important to consider the competitive pro-tobacco context in which antismoking ads will be viewed.

A Primer on Value-Added Models: Towards a Better Understanding of the Quantitative Analysis of Student Achievement

ERIC Educational Resources Information Center

Nakamura, Yugo

2013-01-01

Value-added models (VAMs) have received considerable attention as a tool to transform our public education system. However, as VAMs are studied by researchers from a broad range of academic disciplines who remain divided over the best methods in analyzing the models and stakeholders without the extensive statistical background have been excluded…

Massless spinning particle and null-string on AdS d : projective-space approach

NASA Astrophysics Data System (ADS)

Uvarov, D. V.

2018-07-01

The massless spinning particle and the tensionless string models on an AdS d background in the projective-space realization are proposed as constrained Hamiltonian systems. Various forms of particle and string Lagrangians are derived and classical mechanics is studied including the Lax-type representation of the equations of motion. After that, the transition to the quantum theory is discussed. The analysis of potential anomalies in the tensionless string model necessitates the introduction of ghosts and BRST charge. It is shown that a quantum BRST charge is nilpotent for any d if coordinate-momentum ordering for the phase-space bosonic variables, Weyl ordering for the fermions and cb () ordering for the ghosts is chosen, while conformal reparametrizations and space-time dilatations turn out to be anomalous for ordering in terms of positive and negative Fourier modes of the phase-space variables and ghosts.

Introducing ADS 2.0

NASA Astrophysics Data System (ADS)

Accomazzi, Alberto; Kurtz, M. J.; Henneken, E. A.; Grant, C. S.; Thompson, D.; Luker, J.; Chyla, R.; Murray, S. S.

2014-01-01

In the spring of 1993, the Smithsonian/NASA Astrophysics Data System (ADS) first launched its bibliographic search system. It was known then as the ADS Abstract Service, a component of the larger Astrophysics Data System effort which had developed an interoperable data system now seen as a precursor of the Virtual Observatory. As a result of the massive technological and sociological changes in the field of scholarly communication, the ADS is now completing the most ambitious technological upgrade in its twenty-year history. Code-named ADS 2.0, the new system features: an IT platform built on web and digital library standards; a new, extensible, industrial strength search engine; a public API with various access control capabilities; a set of applications supporting search, export, visualization, analysis; a collaborative, open source development model; and enhanced indexing of content which includes the full-text of astronomy and physics publications. The changes in the ADS platform affect all aspects of the system and its operations, including: the process through which data and metadata are harvested, curated and indexed; the interface and paradigm used for searching the database; and the follow-up analysis capabilities available to the users. This poster describes the choices behind the technical overhaul of the system, the technology stack used, and the opportunities which the upgrade is providing us with, namely gains in productivity and enhancements in our system capabilities.

Spiral Galaxy Lensing: A Model with Twist

NASA Astrophysics Data System (ADS)

Bell, Steven R.; Ernst, Brett; Fancher, Sean; Keeton, Charles R.; Komanduru, Abi; Lundberg, Erik

2014-12-01

We propose a single galaxy gravitational lensing model with a mass density that has a spiral structure. Namely, we extend the arcsine gravitational lens (a truncated singular isothermal elliptical model), adding an additional parameter that controls the amount of spiraling in the structure of the mass density. An important feature of our model is that, even though the mass density is sophisticated, we succeed in integrating the deflection term in closed form using a Gauss hypergeometric function. When the spiraling parameter is set to zero, this reduces to the arcsine lens.

Parametric Mass Modeling for Mars Entry, Descent and Landing System Analysis Study

NASA Technical Reports Server (NTRS)

Samareh, Jamshid A.; Komar, D. R.

2011-01-01

This paper provides an overview of the parametric mass models used for the Entry, Descent, and Landing Systems Analysis study conducted by NASA in FY2009-2010. The study examined eight unique exploration class architectures that included elements such as a rigid mid-L/D aeroshell, a lifting hypersonic inflatable decelerator, a drag supersonic inflatable decelerator, a lifting supersonic inflatable decelerator implemented with a skirt, and subsonic/supersonic retro-propulsion. Parametric models used in this study relate the component mass to vehicle dimensions and mission key environmental parameters such as maximum deceleration and total heat load. The use of a parametric mass model allows the simultaneous optimization of trajectory and mass sizing parameters.

Advertising health: the case for counter-ads.

PubMed Central

Dorfman, L; Wallack, L

1993-01-01

Public service advertisements have been used by many in hopes of "selling" good health behaviors. But selling good behavior--even if it could be done more effectively--is not the best goal for using mass media to prevent health problems. Personal behavior is only part of what determines health status. Social conditions and the physical environment are important determinants of health that are usually ignored by health promotion advertising. Public service advertising may be doing more harm than good if it is diverting attention from more effective socially based health promotion strategies. Counter-ads are one communications strategy that could be used to promote a broader responsibility for rectifying health problems. In the tradition of advocacy advertising directly promoting policy rather than products, counter-ads promote views consistent with a public health perspective. Counter-ads set the agenda for health issues, conferring status on policy-oriented strategies for addressing health problems. The primary purpose of counter-ads is to challenge the dominant view that public health problems reflect personal health habits. They are controversial because they place health issues in a social and political context. Advertising strategies for health promotion range over a spectrum from individually oriented public service advertising to socially oriented counter-advertising. The recent anti-tobacco campaign from the California Department of Health Services represents advertisements across the spectrum. Counter-ads that focus on a politically controversial definition for health problems are an appropriate and necessary alternative to public service advertising. PMID:8265756

Advertising health: the case for counter-ads.

PubMed

Dorfman, L; Wallack, L

1993-01-01

Public service advertisements have been used by many in hopes of "selling" good health behaviors. But selling good behavior--even if it could be done more effectively--is not the best goal for using mass media to prevent health problems. Personal behavior is only part of what determines health status. Social conditions and the physical environment are important determinants of health that are usually ignored by health promotion advertising. Public service advertising may be doing more harm than good if it is diverting attention from more effective socially based health promotion strategies. Counter-ads are one communications strategy that could be used to promote a broader responsibility for rectifying health problems. In the tradition of advocacy advertising directly promoting policy rather than products, counter-ads promote views consistent with a public health perspective. Counter-ads set the agenda for health issues, conferring status on policy-oriented strategies for addressing health problems. The primary purpose of counter-ads is to challenge the dominant view that public health problems reflect personal health habits. They are controversial because they place health issues in a social and political context. Advertising strategies for health promotion range over a spectrum from individually oriented public service advertising to socially oriented counter-advertising. The recent anti-tobacco campaign from the California Department of Health Services represents advertisements across the spectrum. Counter-ads that focus on a politically controversial definition for health problems are an appropriate and necessary alternative to public service advertising.

Large Black Holes in the Randall-Sundrum II Model

NASA Astrophysics Data System (ADS)

Yaghoobpour Tari, Shima

The Einstein equation with a negative cosmological constant ! in the five dimensions for the Randall-Sundrum II model, which includes a black hole, has been solved numerically. We have constructed an AdS5-CFT 4 solution numerically, using a spectral method to minimize the integral of the square of the error of the Einstein equation, with 210 parameters to be determined by optimization. This metric is conformal to the Schwarzschild metric at an AdS5 boundary with an infinite scale factor. So, we consider this solution as an infinite-mass black hole solution. We have rewritten the infinite-mass black hole in the Fefferman-Graham form and obtained the numerical components of the CFT energy-momentum tensor. Using them, we have perturbed the metric to relocate the brane from infinity and obtained a large static black hole solution for the Randall- Sundrum II model. The changes of mass, entropy, temperature and area of the large black hole from the Schwarzschild metric are studied up to the first order for the perturbation parameter 1/(-Λ5M 2). The Hawking temperature and entropy for our large black hole have the same values as the Schwarzschild metric with the same mass, but the horizon area is increased by about 4.7/(-Λ5). Figueras, Lucietti, and Wiseman found an AdS5-CFT4 solution using an independent and different method from us, called the Ricci-DeTurck-flow method. Then, Figueras and Wiseman perturbed this solution in a same way as we have done and obtained the solution for the large black hole in the Randall-Sundrum II model. These two numerical solutions are the first mathematical proofs for having a large black hole in the Randall-Sundrum II. We have compared their results with ours for the CFT energy-momentum tensor components and the perturbed metric. We have shown that the results are closely in agreement, which can be considered as evidence that the solution for the large black hole in the Randall-Sundrum II model exists.

Two-loop renormalization of gaugino masses in general supersymmetric gauge models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yamada, Y.

1994-01-03

We calculate the two-loop renormalization group equations for the running gaugino masses in general supersymmetry (SUSY) gauge models, improving our previous result. We also study its consequences on the unification of the gaugino masses in the SUSY SU(5) model. The two-loop correction to the one-loop relation [ital m][sub [ital i

Value Added Models and the Implementation of the National Standards of K-12 Physical Education

ERIC Educational Resources Information Center

Seymour, Clancy M.; Garrison, Mark J.

2017-01-01

The implementation of value-added models of teacher evaluation continue to expand in public education, but the effects of using student test scores to evaluate K-12 physical educators necessitates further discussion. Using the five National Standards for K-12 Physical Education from the Society of Health and Physical Educators America (SHAPE),…

Loops in AdS from conformal field theory

DOE PAGES

Aharony, Ofer; Alday, Luis F.; Bissi, Agnese; ...

2017-07-10

We propose and demonstrate a new use for conformal field theory (CFT) crossing equations in the context of AdS/CFT: the computation of loop amplitudes in AdS, dual to non-planar correlators in holographic CFTs. Loops in AdS are largely unexplored, mostly due to technical difficulties in direct calculations. We revisit this problem, and the dual 1=N expansion of CFTs, in two independent ways. The first is to show how to explicitly solve the crossing equations to the first subleading order in 1=N 2, given a leading order solution. This is done as a systematic expansion in inverse powers of the spin, to all orders. These expansions can be resummed, leading to the CFT data for nite values of the spin. Our second approach involves Mellin space. We show how the polar part of the four-point, loop-level Mellin amplitudes can be fully reconstructed from the leading-order data. The anomalous dimensions computed with both methods agree. In the case ofmore » $$\\phi$$ 4 theory in AdS, our crossing solution reproduces a previous computation of the one-loop bubble diagram. We can go further, deriving the four-point scalar triangle diagram in AdS, which had never been computed. In the process, we show how to analytically derive anomalous dimensions from Mellin amplitudes with an in nite series of poles, and discuss applications to more complicated cases such as the N = 4 super-Yang-Mills theory.« less

Loops in AdS from conformal field theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aharony, Ofer; Alday, Luis F.; Bissi, Agnese

We propose and demonstrate a new use for conformal field theory (CFT) crossing equations in the context of AdS/CFT: the computation of loop amplitudes in AdS, dual to non-planar correlators in holographic CFTs. Loops in AdS are largely unexplored, mostly due to technical difficulties in direct calculations. We revisit this problem, and the dual 1=N expansion of CFTs, in two independent ways. The first is to show how to explicitly solve the crossing equations to the first subleading order in 1=N 2, given a leading order solution. This is done as a systematic expansion in inverse powers of the spin, to all orders. These expansions can be resummed, leading to the CFT data for nite values of the spin. Our second approach involves Mellin space. We show how the polar part of the four-point, loop-level Mellin amplitudes can be fully reconstructed from the leading-order data. The anomalous dimensions computed with both methods agree. In the case ofmore » $$\\phi$$ 4 theory in AdS, our crossing solution reproduces a previous computation of the one-loop bubble diagram. We can go further, deriving the four-point scalar triangle diagram in AdS, which had never been computed. In the process, we show how to analytically derive anomalous dimensions from Mellin amplitudes with an in nite series of poles, and discuss applications to more complicated cases such as the N = 4 super-Yang-Mills theory.« less

Loops in AdS from conformal field theory

NASA Astrophysics Data System (ADS)

Aharony, Ofer; Alday, Luis F.; Bissi, Agnese; Perlmutter, Eric

2017-07-01

We propose and demonstrate a new use for conformal field theory (CFT) crossing equations in the context of AdS/CFT: the computation of loop amplitudes in AdS, dual to non-planar correlators in holographic CFTs. Loops in AdS are largely unexplored, mostly due to technical difficulties in direct calculations. We revisit this problem, and the dual 1 /N expansion of CFTs, in two independent ways. The first is to show how to explicitly solve the crossing equations to the first subleading order in 1 /N 2, given a leading order solution. This is done as a systematic expansion in inverse powers of the spin, to all orders. These expansions can be resummed, leading to the CFT data for finite values of the spin. Our second approach involves Mellin space. We show how the polar part of the four-point, loop-level Mellin amplitudes can be fully reconstructed from the leading-order data. The anomalous dimensions computed with both methods agree. In the case of ϕ 4 theory in AdS, our crossing solution reproduces a previous computation of the one-loop bubble diagram. We can go further, deriving the four-point scalar triangle diagram in AdS, which had never been computed. In the process, we show how to analytically derive anomalous dimensions from Mellin amplitudes with an infinite series of poles, and discuss applications to more complicated cases such as the N = 4 super-Yang-Mills theory.

Assessing mass change trends in GRACE models

NASA Astrophysics Data System (ADS)

Siemes, C.; Liu, X.; Ditmar, P.; Revtova, E.; Slobbe, C.; Klees, R.; Zhao, Q.

2009-04-01

The DEOS Mass Transport model, release 1 (DMT-1), has been recently presented to the scientific community. The model is based on GRACE data and consists of sets of spherical harmonic coefficients to degree 120, which are estimated once per month. Currently, the DMT-1 model covers the time span from Feb. 2003 to Dec. 2006. The high spatial resolution of the model could be achieved by applying a statistically optimal Wiener-type filter, which is superior to standard filtering techniques. The optimal Wiener-type filter is a regularization-type filter which makes full use of the variance/covariance matrices of the sets of spherical harmonic coefficients. It can be shown that applying this filter is equivalent to introducing an additional set of observations: Each set of spherical harmonic coefficients is assumed to be zero. The variance/covariance matrix of this information is chosen according to the signal contained within the sets of spherical harmonic coefficients, expressed in terms of equivalent water layer thickness in the spatial domain, with respect to its variations in time. It will be demonstrated that DMT-1 provides a much better localization and more realistic amplitudes than alternative filtered models. In particular, we will consider a lower maximum degree of the spherical harmonic expansion (e.g. 70), as well as standard filters like an isotropic Gaussian filter. For the sake of a fair comparison, we will use the same GRACE observations as well as the same method for the inversion of the observations to obtain the alternative filtered models. For the inversion method, we will choose the three-point range combination approach. Thus, we will compare four different models: (1) GRACE solution with maximum degree 120, filtered by optimal Wiener-type filter (the DMT-1 model) (2) GRACE solution with maximum degree 120, filtered by standard filter (3) GRACE solution with maximum degree 70, filtered by optimal Wiener-type filter (4) GRACE solution with maximum

Minimal model linking two great mysteries: Neutrino mass and dark matter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farzan, Yasaman

2009-10-01

We present an economic model that establishes a link between neutrino masses and properties of the dark matter candidate. The particle content of the model can be divided into two groups: light particles with masses lighter than the electroweak scale and heavy particles. The light particles, which also include the dark matter candidate, are predicted to show up in the low energy experiments such as (K{yields}l+missing energy), making the model testable. The heavy sector can show up at the LHC and may give rise to Br(l{sub i}{yields}l{sub j}{gamma}) close to the present bounds. In principle, the new couplings of themore » model can independently be derived from the data from the LHC and from the information on neutrino masses and lepton flavor violating rare decays, providing the possibility of an intensive cross-check of the model.« less

Neuroprotective Effect of SLM, a Novel Carbazole-Based Fluorophore, on SH-SY5Y Cell Model and 3xTg-AD Mouse Model of Alzheimer's Disease.

PubMed

Wu, Xiaoli; Kosaraju, Jayasankar; Zhou, Wei; Tam, Kin Yip

2017-03-15

Amyloid β (Aβ) peptide aggregating to form a neurotoxic plaque, leading to cognitive deficits, is believed to be one of the plausible mechanisms for Alzheimer's disease (AD). Inhibiting Aβ aggregation is supposed to offer a neuroprotective effect to ameliorate AD. A previous report has shown that SLM, a carbazole-based fluorophore, binds to Aβ to inhibit the aggregation. However, it is not entirely clear whether the inhibition of Aβ aggregation alone would lead to the anticipated neuroprotective effects. In the current study, we intended to examine the protective action of SLM against Aβ-induced neurotoxicity in vitro and to evaluate if SLM can decrease the cognitive and behavioral deficits observed in triple transgenic AD mouse model (3xTg-AD). In the in vitro study, neurotoxicity induced by Aβ42 in human neuroblastoma (SH-SY5Y) cells was found to be reduced through the treatment with SLM. In the in vivo study, following one month SLM intraperitoneal injection (1, 2, and 4 mg/kg), 3xTg-AD mice were tested on Morris water maze (MWM) and Y-maze for their cognitive ability and sacrificed for biochemical estimations. Results show that SLM treatment improved the learning and memory ability in 3xTg-AD mice in MWM and Y-maze tasks. SLM also mitigated the amyloid burden by decreasing brain Aβ40 and Aβ42 levels and reduced tau phosphorylation, glycogen synthase kinase-3β activity, and neuro-inflammation. From our observations, SLM shows neuroprotection in SH-SY5Y cells against Aβ42 and also in 3xTg-AD mouse model by mitigating the pathological features and behavioral impairments.

Calibrating a surface mass-balance model for Austfonna ice cap, Svalbard

NASA Astrophysics Data System (ADS)

Schuler, Thomas Vikhamar; Loe, Even; Taurisano, Andrea; Eiken, Trond; Hagen, Jon Ove; Kohler, Jack

2007-10-01

Austfonna (8120 km2) is by far the largest ice mass in the Svalbard archipelago. There is considerable uncertainty about its current state of balance and its possible response to climate change. Over the 2004/05 period, we collected continuous meteorological data series from the ice cap, performed mass-balance measurements using a network of stakes distributed across the ice cap and mapped the distribution of snow accumulation using ground-penetrating radar along several profile lines. These data are used to drive and test a model of the surface mass balance. The spatial accumulation pattern was derived from the snow depth profiles using regression techniques, and ablation was calculated using a temperature-index approach. Model parameters were calibrated using the available field data. Parameter calibration was complicated by the fact that different parameter combinations yield equally acceptable matches to the stake data while the resulting calculated net mass balance differs considerably. Testing model results against multiple criteria is an efficient method to cope with non-uniqueness. In doing so, a range of different data and observations was compared to several different aspects of the model results. We find a systematic underestimation of net balance for parameter combinations that predict observed ice ablation, which suggests that refreezing processes play an important role. To represent these effects in the model, a simple PMAX approach was included in its formulation. Used as a diagnostic tool, the model suggests that the surface mass balance for the period 29 April 2004 to 23 April 2005 was negative (-318 mm w.e.).

Volume-weighted particle-tracking method for solute-transport modeling; Implementation in MODFLOW–GWT

USGS Publications Warehouse

Winston, Richard B.; Konikow, Leonard F.; Hornberger, George Z.

2018-02-16

In the traditional method of characteristics for groundwater solute-transport models, advective transport is represented by moving particles that track concentration. This approach can lead to global mass-balance problems because in models of aquifers having complex boundary conditions and heterogeneous properties, particles can originate in cells having different pore volumes and (or) be introduced (or removed) at cells representing fluid sources (or sinks) of varying strengths. Use of volume-weighted particles means that each particle tracks solute mass. In source or sink cells, the changes in particle weights will match the volume of water added or removed through external fluxes. This enables the new method to conserve mass in source or sink cells as well as globally. This approach also leads to potential efficiencies by allowing the number of particles per cell to vary spatially—using more particles where concentration gradients are high and fewer where gradients are low. The approach also eliminates the need for the model user to have to distinguish between “weak” and “strong” fluid source (or sink) cells. The new model determines whether solute mass added by fluid sources in a cell should be represented by (1) new particles having weights representing appropriate fractions of the volume of water added by the source, or (2) distributing the solute mass added over all particles already in the source cell. The first option is more appropriate for the condition of a strong source; the latter option is more appropriate for a weak source. At sinks, decisions whether or not to remove a particle are replaced by a reduction in particle weight in proportion to the volume of water removed. A number of test cases demonstrate that the new method works well and conserves mass. The method is incorporated into a new version of the U.S. Geological Survey’s MODFLOW–GWT solute-transport model.

Modeling Droplet Heat and Mass Transfer during Spray Bar Pressure Control of the Multipurpose Hydrogen Test Bed (MHTB) Tank in Normal Gravity

NASA Technical Reports Server (NTRS)

Kartuzova, O.; Kassemi, M.

2016-01-01

A CFD model for simulating pressure control in cryogenic storage tanks through the injection of a subcooled liquid into the ullage is presented and applied to the 1g MHTB spray bar cooling experiments. An Eulerian-Lagrangian approach is utilized to track the spray droplets and capture the interaction between the discrete droplets and the continuous ullage phase. The spray model is coupled with the VOF model by performing particle tracking in the ullage, removing particles from the ullage when they reach the interface, and then adding their contributions to the liquid. A new model for calculating the droplet-ullage heat and mass transfer is developed. In this model, a droplet is allowed to warm up to the saturation temperature corresponding to the ullage vapor pressure, after which it evaporates while remaining at the saturation temperature. The droplet model is validated against the results of the MHTB spray-bar cooling experiments with 50% and 90% tank fill ratios. The predictions of the present T-sat based model are compared with those of a previously developed kinetic-based droplet mass transfer model. The predictions of the two models regarding the evolving tank pressure and temperature distributions, as well as the droplets' trajectories and temperatures, are examined and compared in detail. Finally, the ullage pressure and local vapor and liquid temperature evolutions are validated against the corresponding data provided by the MHTB spray bar mixing experiment.

GROUNDWATER MASS TRANSPORT AND EQUILIBRIUM CHEMISTRY MODEL FOR MULTICOMPONENT SYSTEMS

EPA Science Inventory

A mass transport model, TRANQL, for a multicomponent solution system has been developed. The equilibrium interaction chemistry is posed independently of the mass transport equations which leads to a set of algebraic equations for the chemistry coupled to a set of differential equ...

Worldsheet scattering in AdS3/CFT2

NASA Astrophysics Data System (ADS)

Sundin, Per; Wulff, Linus

2013-07-01

We confront the recently proposed exact S-matrices for AdS 3/ CFT 2 with direct worldsheet calculations. Utilizing the BMN and Near Flat Space (NFS) expansions for strings on AdS 3 × S 3 × S 3 × S 1 and AdS 3 × S 3 × T 4 we compute both tree-level and one-loop scattering amplitudes. Up to some minor issues we find nice agreement in the tree-level sector. At the one-loop level however we find that certain non-zero tree-level processes, which are not visible in the exact solution, contribute, via the optical theorem, and give an apparent mismatch for certain amplitudes. Furthermore we find that a proposed one-loop modification of the dressing phase correctly reproduces the worldsheet calculation while the standard Hernandez-Lopez phase does not. We also compute several massless to massless processes.

Strings on AdS_3 x S^3 and the Plane-Wave Limit. Issues on PP-Wave/CFT Holography

NASA Astrophysics Data System (ADS)

Zapata, Oswaldo

2005-10-01

In this thesis we give explicit results for bosonic string amplitudes on AdS_3 x S^3 and the corresponding plane-wave limit. We also analyze the consequences of our approach for understanding holography in this set up, as well as its possible generalization to other models.

AdS/CFT in string theory and M-theory

NASA Astrophysics Data System (ADS)

Gulotta, Daniel R.

The AdS/CFT correspondence is a powerful tool that can help shed light on the relationship between geometry and field theory. The first part of this thesis will focus on the construction of theories dual to Type IIB string theory on AdS5 × Y5, where Y5 is a toric Sasaki-Einstein manifold. This thesis will introduce a consistency condition called ``proper ordering'' and demonstrate that it is equivalent to several other previously known consistency conditions. It will then give an efficient algorithm that produces a consistent field theory for any toric Sasaki-Einstein Y5. The second part of this thesis will examine the large-N limit of the Kapustin-Willett-Yaakov matrix model. This model computes the S3 partition function for a CFT dual to M-theory on AdS4 × Y7. One of the main results will be a formula that relates the distribution of eigenvalues in the matrix model to the distribution of holomorphic operators on the cone over Y7. A variety of examples are given to support this formula.

Modelling mass and heat transfer in nano-based cancer hyperthermia.

PubMed

Nabil, M; Decuzzi, P; Zunino, P

2015-10-01

We derive a sophisticated mathematical model for coupled heat and mass transport in the tumour microenvironment and we apply it to study nanoparticle delivery and hyperthermic treatment of cancer. The model has the unique ability of combining the following features: (i) realistic vasculature; (ii) coupled capillary and interstitial flow; (iii) coupled capillary and interstitial mass transfer applied to nanoparticles; and (iv) coupled capillary and interstitial heat transfer, which are the fundamental mechanisms governing nano-based hyperthermic treatment. This is an improvement with respect to previous modelling approaches, where the effect of blood perfusion on heat transfer is modelled in a spatially averaged form. We analyse the time evolution and the spatial distribution of particles and temperature in a tumour mass treated with superparamagnetic nanoparticles excited by an alternating magnetic field. By means of numerical experiments, we synthesize scaling laws that illustrate how nano-based hyperthermia depends on tumour size and vascularity. In particular, we identify two distinct mechanisms that regulate the distribution of particle and temperature, which are characterized by perfusion and diffusion, respectively.

Introduction to the AdS/CFT Correspondence

NASA Astrophysics Data System (ADS)

Nąstase, Horaǧiu

2015-09-01

Preface; Introduction; Part I. Background: 1. Elements of quantum field theory and gauge theory; 2. Basics of general relativity. Anti-de Sitter space; 3. Basics of supersymmetry; 4. Basics of supergravity; 5. Kaluza-Klein dimensional reduction; 6. Black holes and p-branes; 7. String theory actions and spectra; 8. Elements of conformal field theory; 9. D-branes; Part II. Basics of AdS/CFT for N = 4 SYM vs AdS5 × S5: 10. The AdS/CFT correspondence: motivation, definition and spectra; 11. Witten prescription and 3-point correlator calculations; 12. Holography in Lorentzian signature: Poincaré and global; 13. Solitonic objects in AdS/CFT; 14. Quarks and the Wilson loop; 15. Finite temperature and N = 4 SYM plasmas; 16. Scattering processes and gravitational shockwave limit; 17. The pp-wave correspondence; 18. Spin chains; Part III. AdS/CFT Developments and Gauge-Gravity Dualities: 19. Other conformal cases; 20. The 3 dimensional ABJM model vs. AdS4 × CP3; 21. Gravity duals; 22. Holographic renormalization; 23. RG flow between fixed points; 24. Phenomenological gauge-gravity duality I: AdS/QCD; 25. Phenomenological gauge-gravity duality II: AdS/CMT; 26. Gluon scattering: the Alday-Maldacena prescription; 27. Holographic entanglement entropy: the Ryu-Takayanagi prescription.

Hierarchical Interactions Model for Predicting Mild Cognitive Impairment (MCI) to Alzheimer's Disease (AD) Conversion

PubMed Central

Li, Han; Liu, Yashu; Gong, Pinghua; Zhang, Changshui; Ye, Jieping

2014-01-01

Identifying patients with Mild Cognitive Impairment (MCI) who are likely to convert to dementia has recently attracted increasing attention in Alzheimer's disease (AD) research. An accurate prediction of conversion from MCI to AD can aid clinicians to initiate treatments at early stage and monitor their effectiveness. However, existing prediction systems based on the original biosignatures are not satisfactory. In this paper, we propose to fit the prediction models using pairwise biosignature interactions, thus capturing higher-order relationship among biosignatures. Specifically, we employ hierarchical constraints and sparsity regularization to prune the high-dimensional input features. Based on the significant biosignatures and underlying interactions identified, we build classifiers to predict the conversion probability based on the selected features. We further analyze the underlying interaction effects of different biosignatures based on the so-called stable expectation scores. We have used 293 MCI subjects from Alzheimer's Disease Neuroimaging Initiative (ADNI) database that have MRI measurements at the baseline to evaluate the effectiveness of the proposed method. Our proposed method achieves better classification performance than state-of-the-art methods. Moreover, we discover several significant interactions predictive of MCI-to-AD conversion. These results shed light on improving the prediction performance using interaction features. PMID:24416143

Greenland Ice Sheet seasonal and spatial mass variability from model simulations and GRACE (2003-2012)

NASA Astrophysics Data System (ADS)

Alexander, Patrick M.; Tedesco, Marco; Schlegel, Nicole-Jeanne; Luthcke, Scott B.; Fettweis, Xavier; Larour, Eric

2016-06-01

Improving the ability of regional climate models (RCMs) and ice sheet models (ISMs) to simulate spatiotemporal variations in the mass of the Greenland Ice Sheet (GrIS) is crucial for prediction of future sea level rise. While several studies have examined recent trends in GrIS mass loss, studies focusing on mass variations at sub-annual and sub-basin-wide scales are still lacking. At these scales, processes responsible for mass change are less well understood and modeled, and could potentially play an important role in future GrIS mass change. Here, we examine spatiotemporal variations in mass over the GrIS derived from the Gravity Recovery and Climate Experiment (GRACE) satellites for the January 2003-December 2012 period using a "mascon" approach, with a nominal spatial resolution of 100 km, and a temporal resolution of 10 days. We compare GRACE-estimated mass variations against those simulated by the Modèle Atmosphérique Régionale (MAR) RCM and the Ice Sheet System Model (ISSM). In order to properly compare spatial and temporal variations in GrIS mass from GRACE with model outputs, we find it necessary to spatially and temporally filter model results to reproduce leakage of mass inherent in the GRACE solution. Both modeled and satellite-derived results point to a decline (of -178.9 ± 4.4 and -239.4 ± 7.7 Gt yr-1 respectively) in GrIS mass over the period examined, but the models appear to underestimate the rate of mass loss, especially in areas below 2000 m in elevation, where the majority of recent GrIS mass loss is occurring. On an ice-sheet-wide scale, the timing of the modeled seasonal cycle of cumulative mass (driven by summer mass loss) agrees with the GRACE-derived seasonal cycle, within limits of uncertainty from the GRACE solution. However, on sub-ice-sheet-wide scales, some areas exhibit significant differences in the timing of peaks in the annual cycle of mass change. At these scales, model biases, or processes not accounted for by models related

EVOLUTIONARY MODELS OF SUPER-EARTHS AND MINI-NEPTUNES INCORPORATING COOLING AND MASS LOSS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Howe, Alex R.; Burrows, Adam, E-mail: arhowe@astro.princeton.edu, E-mail: burrows@astro.princeton.edu

We construct models of the structural evolution of super-Earth- and mini-Neptune-type exoplanets with H{sub 2}–He envelopes, incorporating radiative cooling and XUV-driven mass loss. We conduct a parameter study of these models, focusing on initial mass, radius, and envelope mass fractions, as well as orbital distance, metallicity, and the specific prescription for mass loss. From these calculations, we investigate how the observed masses and radii of exoplanets today relate to the distribution of their initial conditions. Orbital distance and the initial envelope mass fraction are the most important factors determining planetary evolution, particularly radius evolution. Initial mass also becomes important belowmore » a “turnoff mass,” which varies with orbital distance, with mass–radius curves being approximately flat for higher masses. Initial radius is the least important parameter we study, with very little difference between the hot start and cold start limits after an age of 100 Myr. Model sets with no mass loss fail to produce results consistent with observations, but a plausible range of mass-loss scenarios is allowed. In addition, we present scenarios for the formation of the Kepler-11 planets. Our best fit to observations of Kepler-11b and Kepler-11c involves formation beyond the snow line, after which they moved inward, circularized, and underwent a reduced degree of mass loss.« less

MassTRIX: mass translator into pathways.

PubMed

Suhre, Karsten; Schmitt-Kopplin, Philippe

2008-07-01

Recent technical advances in mass spectrometry (MS) have brought the field of metabolomics to a point where large numbers of metabolites from numerous prokaryotic and eukaryotic organisms can now be easily and precisely detected. The challenge today lies in the correct annotation of these metabolites on the basis of their accurate measured masses. Assignment of bulk chemical formula is generally possible, but without consideration of the biological and genomic context, concrete metabolite annotations remain difficult and uncertain. MassTRIX responds to this challenge by providing a hypothesis-driven approach to high precision MS data annotation. It presents the identified chemical compounds in their genomic context as differentially colored objects on KEGG pathway maps. Information on gene transcription or differences in the gene complement (e.g. samples from different bacterial strains) can be easily added. The user can thus interpret the metabolic state of the organism in the context of its potential and, in the case of submitted transcriptomics data, real enzymatic capacities. The MassTRIX web server is freely accessible at http://masstrix.org.

Adding thin-ideal internalization and impulsiveness to the cognitive-behavioral model of bulimic symptoms.

PubMed

Schnitzler, Caroline E; von Ranson, Kristin M; Wallace, Laurel M

2012-08-01

This study evaluated the cognitive-behavioral (CB) model of bulimia nervosa and an extension that included two additional maintaining factors - thin-ideal internalization and impulsiveness - in 327 undergraduate women. Participants completed measures of demographics, self-esteem, concern about shape and weight, dieting, bulimic symptoms, thin-ideal internalization, and impulsiveness. Both the original CB model and the extended model provided good fits to the data. Although structural equation modeling analyses suggested that the original CB model was most parsimonious, hierarchical regression analyses indicated that the additional variables accounted for significantly more variance. Additional analyses showed that the model fit could be improved by adding a path from concern about shape and weight, and deleting the path from dieting, to bulimic symptoms. Expanding upon the factors considered in the model may better capture the scope of variables maintaining bulimic symptoms in young women with a range of severity of bulimic symptoms. Copyright © 2012 Elsevier Ltd. All rights reserved.

Impact of plant shoot architecture on leaf cooling: a coupled heat and mass transfer model

PubMed Central

Bridge, L. J.; Franklin, K. A.; Homer, M. E.

2013-01-01

Plants display a range of striking architectural adaptations when grown at elevated temperatures. In the model plant Arabidopsis thaliana, these include elongation of petioles, and increased petiole and leaf angles from the soil surface. The potential physiological significance of these architectural changes remains speculative. We address this issue computationally by formulating a mathematical model and performing numerical simulations, testing the hypothesis that elongated and elevated plant configurations may reflect a leaf-cooling strategy. This sets in place a new basic model of plant water use and interaction with the surrounding air, which couples heat and mass transfer within a plant to water vapour diffusion in the air, using a transpiration term that depends on saturation, temperature and vapour concentration. A two-dimensional, multi-petiole shoot geometry is considered, with added leaf-blade shape detail. Our simulations show that increased petiole length and angle generally result in enhanced transpiration rates and reduced leaf temperatures in well-watered conditions. Furthermore, our computations also reveal plant configurations for which elongation may result in decreased transpiration rate owing to decreased leaf liquid saturation. We offer further qualitative and quantitative insights into the role of architectural parameters as key determinants of leaf-cooling capacity. PMID:23720538

A high throughput MATLAB program for automated force-curve processing using the AdG polymer model.

PubMed

O'Connor, Samantha; Gaddis, Rebecca; Anderson, Evan; Camesano, Terri A; Burnham, Nancy A

2015-02-01

Research in understanding biofilm formation is dependent on accurate and representative measurements of the steric forces related to brush on bacterial surfaces. A MATLAB program to analyze force curves from an AFM efficiently, accurately, and with minimal user bias has been developed. The analysis is based on a modified version of the Alexander and de Gennes (AdG) polymer model, which is a function of equilibrium polymer brush length, probe radius, temperature, separation distance, and a density variable. Automating the analysis reduces the amount of time required to process 100 force curves from several days to less than 2min. The use of this program to crop and fit force curves to the AdG model will allow researchers to ensure proper processing of large amounts of experimental data and reduce the time required for analysis and comparison of data, thereby enabling higher quality results in a shorter period of time. Copyright © 2014 Elsevier B.V. All rights reserved.

A flavor symmetry model for bilarge leptonic mixing and the lepton masses

NASA Astrophysics Data System (ADS)

Ohlsson, Tommy; Seidl, Gerhart

2002-11-01

We present a model for leptonic mixing and the lepton masses based on flavor symmetries and higher-dimensional mass operators. The model predicts bilarge leptonic mixing (i.e., the mixing angles θ12 and θ23 are large and the mixing angle θ13 is small) and an inverted hierarchical neutrino mass spectrum. Furthermore, it approximately yields the experimental hierarchical mass spectrum of the charged leptons. The obtained values for the leptonic mixing parameters and the neutrino mass squared differences are all in agreement with atmospheric neutrino data, the Mikheyev-Smirnov-Wolfenstein large mixing angle solution of the solar neutrino problem, and consistent with the upper bound on the reactor mixing angle. Thus, we have a large, but not close to maximal, solar mixing angle θ12, a nearly maximal atmospheric mixing angle θ23, and a small reactor mixing angle θ13. In addition, the model predicts θ 12≃ {π}/{4}-θ 13.

A New Low Mass for the Hercules dSph: The End of a Common Mass Scale for the Dwarfs?

NASA Astrophysics Data System (ADS)

Adén, D.; Wilkinson, M. I.; Read, J. I.; Feltzing, S.; Koch, A.; Gilmore, G. F.; Grebel, E. K.; Lundström, I.

2009-11-01

We present a new mass estimate for the Hercules dwarf spheroidal (dSph) galaxy, based on the revised velocity dispersion obtained by Adén et al. The removal of a significant foreground contamination using newly acquired Strömgren photometry has resulted in a reduced velocity dispersion. Using this new velocity dispersion of 3.72 ± 0.91 km s-1, we find a mass of M 300 = 1.9+1.1 -0.8 × 106 M sun within the central 300 pc, which is also the half-light radius, and a mass of M 433 = 3.7+2.2 -1.6 × 106 M sun within the reach of our data to 433 pc, significantly lower than previous estimates. We derive an overall mass-to-light ratio of M 433/L = 103+83 -48[M sun/L sun]. Our mass estimate calls into question recent claims of a common mass scale for dSph galaxies. Additionally, we find tentative evidence for a velocity gradient in our kinematic data of 16 ± 3 km s-1 kpc-1, and evidence of an asymmetric extension in the light distribution at ~0.5 kpc. We explore the possibility that these features are due to tidal interactions with the Milky Way. We show that there is a self-consistent model in which Hercules has an assumed tidal radius of rt = 485 pc, an orbital pericenter of rp = 18.5 ± 5 kpc, and a mass within rt of M_{tid,r_t}=5.2_{-2.7}^{+2.7} × 10^6 M_⊙. Proper motions are required to test this model. Although we cannot exclude models in which Hercules contains no dark matter, we argue that Hercules is more likely to be a dark-matter-dominated system that is currently experiencing some tidal disturbance of its outer parts.

Homogenization limit for a multiband effective mass model in heterostructures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morandi, O., E-mail: morandi@ipcms.unistra.fr

We study the homogenization limit of a multiband model that describes the quantum mechanical motion of an electron in a quasi-periodic crystal. In this approach, the distance among the atoms that constitute the material (lattice parameter) is considered a small quantity. Our model include the description of materials with variable chemical composition, intergrowth compounds, and heterostructures. We derive the effective multiband evolution system in the framework of the kp approach. We study the well posedness of the mathematical problem. We compare the effective mass model with the standard kp models for uniform and non-uniforms crystals. We show that in themore » limit of vanishing lattice parameter, the particle density obtained by the effective mass model, converges to the exact probability density of the particle.« less

Modeling non-equilibrium mass transport in biologically reactive porous media

NASA Astrophysics Data System (ADS)

Davit, Yohan; Debenest, Gérald; Wood, Brian D.; Quintard, Michel

2010-09-01

We develop a one-equation non-equilibrium model to describe the Darcy-scale transport of a solute undergoing biodegradation in porous media. Most of the mathematical models that describe the macroscale transport in such systems have been developed intuitively on the basis of simple conceptual schemes. There are two problems with such a heuristic analysis. First, it is unclear how much information these models are able to capture; that is, it is not clear what the model's domain of validity is. Second, there is no obvious connection between the macroscale effective parameters and the microscopic processes and parameters. As an alternative, a number of upscaling techniques have been developed to derive the appropriate macroscale equations that are used to describe mass transport and reactions in multiphase media. These approaches have been adapted to the problem of biodegradation in porous media with biofilms, but most of the work has focused on systems that are restricted to small concentration gradients at the microscale. This assumption, referred to as the local mass equilibrium approximation, generally has constraints that are overly restrictive. In this article, we devise a model that does not require the assumption of local mass equilibrium to be valid. In this approach, one instead requires only that, at sufficiently long times, anomalous behaviors of the third and higher spatial moments can be neglected; this, in turn, implies that the macroscopic model is well represented by a convection-dispersion-reaction type equation. This strategy is very much in the spirit of the developments for Taylor dispersion presented by Aris (1956). On the basis of our numerical results, we carefully describe the domain of validity of the model and show that the time-asymptotic constraint may be adhered to even for systems that are not at local mass equilibrium.

Thermospheric Mass Density Specification: Synthesis of Observations and Models

DTIC Science & Technology

2013-10-21

Simulation Experiments (OSSEs) of the column-integrated ratio of atomic oxygen and molecular nitrogen. Note that OSSEs assimilate, for a given...realistic observing system, synthetically generated observational data often sampled from model simulation results, in place of actually observed values...and molecular oxygen mass mixing ratio). Note that in the TIEGCM the molecular nitrogen mass mixing ratio is specified so that the sum of mixing

MODELLING SEDIMENT TRANSPORT FOR THE LAKE MICHIGAN MASS BALANCE PROJECT

EPA Science Inventory

A sediment transport model is one component of the overall ensemble of models being developed for the Lake Michigan Mass Balance. The SEDZL model is being applied to simulate the fine-grained sediment transport in Lake Michigan for the 1982-1983 and 1994-1995 periods. Model perf...

Holography in Lovelock Chern-Simons AdS gravity

NASA Astrophysics Data System (ADS)

Cvetković, Branislav; Miskovic, Olivera; Simić, Dejan

2017-08-01

We analyze holographic field theory dual to Lovelock Chern-Simons anti-de Sitter (AdS) gravity in higher dimensions using first order formalism. We first find asymptotic symmetries in the AdS sector showing that they consist of local translations, local Lorentz rotations, dilatations and non-Abelian gauge transformations. Then, we compute 1-point functions of energy-momentum and spin currents in a dual conformal field theory and write Ward identities. We find that the holographic theory possesses Weyl anomaly and also breaks non-Abelian gauge symmetry at the quantum level.

DEVELOPMENT OF A CONTAMINANT TRANSPORT AND FATE MASS BALANCE CALIBRATION MODEL FOR LAKE MICHIGAN MASS BALANCE PROJECT (LMMBP)

EPA Science Inventory

Lake Michigan Mass Balance Project (LMMBP) was initiated to directly support the development of a lakewide management plan (LaMP) for Lake Michigan. A mass balance modeling approach is proposed for the project to addrss the realtionship between sources of toxic chemicals and thei...

An AD100 implementation of a real-time STOVL aircraft propulsion system

NASA Technical Reports Server (NTRS)

Ouzts, Peter J.; Drummond, Colin K.

1990-01-01

A real-time dynamic model of the propulsion system for a Short Take-Off and Vertical Landing (STOVL) aircraft was developed for the AD100 simulation environment. The dynamic model was adapted from a FORTRAN based simulation using the dynamic programming capabilities of the AD100 ADSIM simulation language. The dynamic model includes an aerothermal representation of a turbofan jet engine, actuator and sensor models, and a multivariable control system. The AD100 model was tested for agreement with the FORTRAN model and real-time execution performance. The propulsion system model was also linked to an airframe dynamic model to provide an overall STOVL aircraft simulation for the purposes of integrated flight and propulsion control studies. An evaluation of the AD100 system for use as an aircraft simulation environment is included.

Test of a chromomagnetic model for hadron mass differences

NASA Astrophysics Data System (ADS)

Lichtenberg, D. B.; Roncaglia, R.

1993-05-01

An oversimplified model consisting of the QCD color-magnetic interaction has been used previously by Silvestre-Brac and others to compare the masses of exotic and normal hadrons. We show that the model can give qualitatively wrong answers when applied to systems of normal hadrons.

Adapted head- and eye-movement responses to added-head inertia

NASA Technical Reports Server (NTRS)

Gauthier, G. M.; Martin, B. J.; Stark, L. W.

1986-01-01

Adaptation to inertia added to the head was studied in men by mounting masses on a rigidly attached helmet until two- to ten-fold increases of inertia were produced, while an overhead suspension compensated for the weights. The observed changes in the eye and head movement coordination included increased head movement latencies, as well as changes in the eye movement amplitude, and later stabilizing alternate contractions of the neck muscles. Oscillopsia, or continual displacement or instability of the visual world, which is a symptom of a breakdown of space constancy, was prominent and consistent in the perceptual reports of the subjects. Although adaptation resulting from adding inertia to the head occurred much faster than that induced by adding prisms or lenses, it has similar perceptual and motor components that may be objectively studied in detail.

Higgs mass and muon anomalous magnetic moment in supersymmetric models with vectorlike matters

DOE Office of Scientific and Technical Information (OSTI.GOV)

Endo, Motoi; Hamaguchi, Koichi; Institute for the Physics and Mathematics of the Universe

2011-10-01

We study the muon anomalous magnetic moment (muon g-2) and the Higgs boson mass in a simple extension of the minimal supersymmetric (SUSY) standard model with extra vectorlike matters, in the frameworks of gauge-mediated SUSY breaking (GMSB) models and gravity mediation (mSUGRA) models. It is shown that the deviation of the muon g-2 and a relatively heavy Higgs boson can be simultaneously explained in large tan{beta} region. (i) In GMSB models, the Higgs mass can be more than 135 GeV (130 GeV) in the region where the muon g-2 is consistent with the experimental value at the 2{sigma} (1{sigma}) level,more » while maintaining the perturbative coupling unification. (ii) In the case of mSUGRA models with universal soft masses, the Higgs mass can be as large as about 130 GeV when the muon g-2 is consistent with the experimental value at the 2{sigma} level. In both cases, the Higgs mass can be above 140 GeV if the g-2 constraint is not imposed.« less

Gauge boson exchange in AdS d+1

NASA Astrophysics Data System (ADS)

D'Hoker, Eric; Freedman, Daniel Z.

1999-04-01

We study the amplitude for exchange of massless gauge bosons between pairs of massive scalar fields in anti-de Sitter space. In the AdS/CFT correspondence this amplitude describes the contribution of conserved flavor symmetry currents to 4-point functions of scalar operators in the boundary conformal theory. A concise, covariant, Y2K compatible derivation of the gauge boson propagator in AdS d + 1 is given. Techniques are developed to calculate the two bulk integrals over AdS space leading to explicit expressions or convenient, simple integral representations for the amplitude. The amplitude contains leading power and sub-leading logarithmic singularities in the gauge boson channel and leading logarithms in the crossed channel. The new methods of this paper are expected to have other applications in the study of the Maldacena conjecture.

Sebestenoids A-D, BACE1 inhibitors from Cordia sebestena.

PubMed

Dai, Jingqiu; Sorribas, Analia; Yoshida, Wesley Y; Williams, Philip G

2010-12-01

Bioassay-guided fractionation of an extract prepared from the fruits of Cordia sebestena led to the isolation of sebestenoids A-D (1-4). Their structures were elucidated on the basis of extensive NMR experiments and mass spectroscopic measurements. Compounds 1-4 exhibited moderate inhibition of the aspartic protease BACE1. Copyright © 2010 Elsevier Ltd. All rights reserved.

Sebestenoids A-D, BACE1 inhibitors from Cordia sebestena

PubMed Central

Dai, Jingqiu; Sorribas, Analia; Yoshida, Wesley Y.; Williams, Philip G.

2010-01-01

Bioassay-guided fractionation of an extract prepared from the fruits of Cordia sebestena has led to the isolation of sebestenoids A-D (1-4). The structures of these new phenylpropanoid esters were elucidated on the basis of extensive NMR experiments and mass spectroscopic measurements. Compounds 1-4 exhibited moderate inhibition of the aspartic protease BACE1. PMID:20952040

From field data to numerical models: application of the Box-Model to infer the dynamics of PDC generated during the AD 79 eruption of Somma-Vesuvio

NASA Astrophysics Data System (ADS)

Tadini, Alessandro; Neri, Augusto; Cioni, Raffaello; Bevilacqua, Andrea; Esposti Ongaro, Tomaso; Gurioli, Lucia

2017-04-01

The purpose of this work is to present a validation procedure for a physical and numerical model of Pyroclastic Density Currents (PDC) using feedbacks from well-known deposits emplaced by specific single eruptive units. The study is specifically focused on the PDCs generated during the overall famous AD 79 eruption of the Somma-Vesuvio volcano. To this purpose, values of the maximum runout, volumes and Total Grain Size Distributions have been estimated for two eruptive units (i.e. EU3pf and EU4; Cioni et al. 2000) of the AD 79 eruption. These units have been used to define the input volcanological parameters for testing the Box-Model of Dade and Huppert (1995), when reproducing one specific end-member of the complex spectrum of PDCs, that is the more dilute, turbulent part of the PDCs reconstructed in the Somma-Vesuvio record (stratified flows with concentration of solid particles in volume up to about 5%). The Box-Model is a kinematic approach, which calculates the flow density and velocity along time and the kinetic energy of the flow front. This can be compared with the potential energy needed to overcome topographic obstacles to estimate flow invasion across complex topographies. Validation of the model has been performed with respect to: i) the degree of overlapping between inundation areas given by the model and by field data; ii) the thickness of the deposit versus the thickness of the model output with distance; iii) the mass fractions of the different grain size classes with distance in the real deposit versus the model output. Several simulations have been performed considering i) polydisperse (with 10 grain size classes) and monodisperse (with the Mdφ values) systems; ii) a direct version (where the initial volume is released and the invasion area is computed) and an inverse version (where the initial collapsing volume is a function of an inundation area defined by the user); iii) axisymmetrical and asymmetrical collapses. Results allow to obtain first

Simulation of the usage of Gaussian mixture models for the purpose of modelling virtual mass spectrometry data.

PubMed

Plechawska, Małgorzata; Polańska, Joanna

2009-01-01

This article presents the method of the processing of mass spectrometry data. Mass spectra are modelled with Gaussian Mixture Models. Every peak of the spectrum is represented by a single Gaussian. Its parameters describe the location, height and width of the corresponding peak of the spectrum. An authorial version of the Expectation Maximisation Algorithm was used to perform all calculations. Errors were estimated with a virtual mass spectrometer. The discussed tool was originally designed to generate a set of spectra within defined parameters.

Modelling Geomechanical Heterogeneity of Rock Masses Using Direct and Indirect Geostatistical Conditional Simulation Methods

NASA Astrophysics Data System (ADS)

Eivazy, Hesameddin; Esmaieli, Kamran; Jean, Raynald

2017-12-01

An accurate characterization and modelling of rock mass geomechanical heterogeneity can lead to more efficient mine planning and design. Using deterministic approaches and random field methods for modelling rock mass heterogeneity is known to be limited in simulating the spatial variation and spatial pattern of the geomechanical properties. Although the applications of geostatistical techniques have demonstrated improvements in modelling the heterogeneity of geomechanical properties, geostatistical estimation methods such as Kriging result in estimates of geomechanical variables that are not fully representative of field observations. This paper reports on the development of 3D models for spatial variability of rock mass geomechanical properties using geostatistical conditional simulation method based on sequential Gaussian simulation. A methodology to simulate the heterogeneity of rock mass quality based on the rock mass rating is proposed and applied to a large open-pit mine in Canada. Using geomechanical core logging data collected from the mine site, a direct and an indirect approach were used to model the spatial variability of rock mass quality. The results of the two modelling approaches were validated against collected field data. The study aims to quantify the risks of pit slope failure and provides a measure of uncertainties in spatial variability of rock mass properties in different areas of the pit.

General structure of democratic mass matrix of quark sector in E6 model

NASA Astrophysics Data System (ADS)

Ciftci, R.; ćiftci, A. K.

2016-03-01

An extension of the Standard Model (SM) fermion sector, which is inspired by the E6 Grand Unified Theory (GUT) model, might be a good candidate to explain a number of unanswered questions in SM. Existence of the isosinglet quarks might explain great mass difference of bottom and top quarks. Also, democracy on mass matrix elements is a natural approach in SM. In this study, we have given general structure of Democratic Mass Matrix (DMM) of quark sector in E6 model.

Next-Generation A/D Sampler ADS3000+ for VLBI2010

NASA Technical Reports Server (NTRS)

Takefuji, Kazuhiro; Takeuchi, Hiroshi; Tsutsumi, Masanori; Koyama, Yasuhiro

2010-01-01

A high-speed A/D sampler, called ADS3000+, has been developed in 2008, which can sample one analog signal up to 4 Gbps to versatile Linux PC. After A/D conversion, the ADS3000+ can perform digital signal processing such as real-time DBBC (Digital Base Band Conversion) and FIR filtering such as simple CW RFI filtering using the installed FPGAs. A 4 Gsps fringe test with the ADS3000+ has been successfully performed. The ADS3000+ will not exclusively be used for VLBI but will also be employed in other applications.

The VIS-AD data model: Integrating metadata and polymorphic display with a scientific programming language

NASA Technical Reports Server (NTRS)

Hibbard, William L.; Dyer, Charles R.; Paul, Brian E.

1994-01-01

The VIS-AD data model integrates metadata about the precision of values, including missing data indicators and the way that arrays sample continuous functions, with the data objects of a scientific programming language. The data objects of this data model form a lattice, ordered by the precision with which they approximate mathematical objects. We define a similar lattice of displays and study visualization processes as functions from data lattices to display lattices. Such functions can be applied to visualize data objects of all data types and are thus polymorphic.

Non-alcoholic fatty liver disease induces signs of Alzheimer's disease (AD) in wild-type mice and accelerates pathological signs of AD in an AD model.

PubMed

Kim, Do-Geun; Krenz, Antje; Toussaint, Leon E; Maurer, Kirk J; Robinson, Sudie-Ann; Yan, Angela; Torres, Luisa; Bynoe, Margaret S

2016-01-05

Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease afflicting about one third of the world's population and 30 % of the US population. It is induced by consumption of high-lipid diets and is characterized by liver inflammation and subsequent liver pathology. Obesity and consumption of a high-fat diet are known to increase the risk of Alzheimer's disease (AD). Here, we investigated NAFLD-induced liver inflammation in the pathogenesis of AD. WT and APP-Tg mice were fed with a standard diet (SD) or a high-fat diet (HFD) for 2, 5 months, or 1 year to induce NAFLD. Another set of APP-Tg mice were removed from HFD after 2 months and put back on SD for 3 months. During acute phase NAFLD, WT and APP-Tg mice developed significant liver inflammation and pathology that coincided with increased numbers of activated microglial cells in the brain, increased inflammatory cytokine profile, and increased expression of toll-like receptors. Chronic NAFLD induced advanced pathological signs of AD in both WT and APP-Tg mice, and also induced neuronal apoptosis. We observed decreased brain expression of low-density lipoprotein receptor-related protein-1 (LRP-1) which is involved in β-amyloid clearance, in both WT and APP-Tg mice after ongoing administration of the HFD. LRP-1 expression correlated with advanced signs of AD over the course of chronic NAFLD. Removal of mice from HFD during acute NAFLD reversed liver pathology, decreased signs of activated microglial cells and neuro-inflammation, and decreased β-amyloid plaque load. Our findings indicate that chronic inflammation induced outside the brain is sufficient to induce neurodegeneration in the absence of genetic predisposition.

Neutrino and C P -even Higgs boson masses in a nonuniversal U (1 )' extension

NASA Astrophysics Data System (ADS)

Mantilla, S. F.; Martinez, R.; Ochoa, F.

2017-05-01

We propose a new anomaly-free and family nonuniversal U (1 )' extension of the standard model with the addition of two scalar singlets and a new scalar doublet. The quark sector is extended by adding three exotic quark singlets, while the lepton sector includes two exotic charged lepton singlets, three right-handed neutrinos, and three sterile Majorana leptons to obtain the fermionic mass spectrum of the standard model. The lepton sector also reproduces the elements of the Pontecorvo-Maki-Nakagawa-Sakata (PMNS) matrix and the squared-mass differences data from neutrino oscillation experiments. Also, analytical relations of the PMNS matrix are derived via the inverse seesaw mechanism, and numerical predictions of the parameters in both normal and inverse order scheme for the mass of the phenomenological neutrinos are obtained. We employed a simple seesawlike method to obtain analytical mass eigenstates of the C P -even 3 ×3 mass matrix of the scalar sector.

Model-independent analysis of quark mass matrices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Choudhury, D.; Sarkar, U.

1989-06-01

In view of the apparent inconsistency of the Stech, Fritzsch-Stech, and Fritzsch-Shin models and only marginal agreement of the Fritzsch and modified Fritzsch-Stech models with recent data on /ital B//sub /ital d///sup 0/-/bar B/ /sub /ital d///sup 0/ mixing, we analyze the general quark mass matrices for three generations. Phenomenological considerations restrict the range of parameters involved to different sectors. In the present framework, the constraints corresponding to various /ital Ansa/$/ital uml/---/ital tze/ have been discussed.

Mass functions from the excursion set model

NASA Astrophysics Data System (ADS)

Hiotelis, Nicos; Del Popolo, Antonino

2017-11-01

Aims: We aim to study the stochastic evolution of the smoothed overdensity δ at scale S of the form δ(S) = ∫0S K(S,u)dW(u), where K is a kernel and dW is the usual Wiener process. Methods: For a Gaussian density field, smoothed by the top-hat filter, in real space, we used a simple kernel that gives the correct correlation between scales. A Monte Carlo procedure was used to construct random walks and to calculate first crossing distributions and consequently mass functions for a constant barrier. Results: We show that the evolution considered here improves the agreement with the results of N-body simulations relative to analytical approximations which have been proposed from the same problem by other authors. In fact, we show that an evolution which is fully consistent with the ideas of the excursion set model, describes accurately the mass function of dark matter haloes for values of ν ≤ 1 and underestimates the number of larger haloes. Finally, we show that a constant threshold of collapse, lower than it is usually used, it is able to produce a mass function which approximates the results of N-body simulations for a variety of redshifts and for a wide range of masses. Conclusions: A mass function in good agreement with N-body simulations can be obtained analytically using a lower than usual constant collapse threshold.

Chromospherically active stars. 12: ADS 11060 C: A double lined K dwarf binary in a quintuple system

NASA Technical Reports Server (NTRS)

Fekel, Francis C.; Henry, Gregory W.; Hampton, Melissa L.; Fried, Robert; Morton, Mary D.

1994-01-01

ADS 11060 C is a double lined spectroscopic binary with a period of 25.7631 days and an eccentricity of 0.565. Spectral types of the two stars are estimated as K7 V and MO V with a magnitude difference of about 0.55 mag in V. The stars appear to be somewhat metal rich with respect to the Sun. Despite the relatively large masses of 0.53 and 0.51 solar mass, our photometric observations find no evidence for eclipses and we estimate an inclination of 77 deg plus or minus 11 deg. ADS 11060 C is, however, photometrically variable with a period of 9 plus or minus 1 day and an amplitude of 0.05 mag in V. Thus, it is a newly identified BY Draconis variable. The center-of-mass velocity of ADS 11060 C and an estimated parallax of 0.030 sec support its physical association with ADS 11060 AB, making this a quintuple system. The projected separation of the AB-C system is nearly 1200 AU. Although the log lithium abundances of the two components of ADS 11060 C are only upper limits, less than or equal to -0.14, lithium abundances of the AB-C components appear to be consistent with those of similar stars in the alpha Persei and Pleiades clusters, suggesting an age of about 70 Myr for ADS 11060 AB-C. The system is a possible member of the Pleiades moving group. Listed as an optical counterpart to a source in the ROSAT Wide Field Camera extreme-ultraviolet bright source catalog, both ADS 11060 AB and C may contribute to the observed flux.

AdS/QCD and Applications of Light-Front Holography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brodsky, Stanley J.; /SLAC /Southern Denmark U., CP3-Origins; Cao, Fu-Guang

2012-02-16

Light-Front Holography leads to a rigorous connection between hadronic amplitudes in a higher dimensional anti-de Sitter (AdS) space and frame-independent light-front wavefunctions of hadrons in 3 + 1 physical space-time, thus providing a compelling physical interpretation of the AdS/CFT correspondence principle and AdS/QCD, a useful framework which describes the correspondence between theories in a modified AdS5 background and confining field theories in physical space-time. To a first semiclassical approximation, where quantum loops and quark masses are not included, this approach leads to a single-variable light-front Schroedinger equation which determines the eigenspectrum and the light-front wavefunctions of hadrons for general spinmore » and orbital angular momentum. The coordinate z in AdS space is uniquely identified with a Lorentz-invariant coordinate {zeta} which measures the separation of the constituents within a hadron at equal light-front time. The internal structure of hadrons is explicitly introduced and the angular momentum of the constituents plays a key role. We give an overview of the light-front holographic approach to strongly coupled QCD. In particular, we study the photon-to-meson transition form factors (TFFs) F{sub M{gamma}}(Q{sup 2}) for {gamma}{gamma}* {yields} M using light-front holographic methods. The results for the TFFs for the {eta} and {eta}' mesons are also presented. Some novel features of QCD are discussed, including the consequences of confinement for quark and gluon condensates. A method for computing the hadronization of quark and gluon jets at the amplitude level is outlined.« less

A Communication Model for Teaching a Course in Mass Media and Society.

ERIC Educational Resources Information Center

Crumley, Wilma; Stricklin, Michael

Many professors of mass media and society courses have relied on a teaching model implying that students are sponges soaking up information. A more appropriate model invites concern with an active audience, transaction, the interpersonal mass media mix, a general systems approach, and process and change--in other words, utilization of current and…

Modeling mass drug treatment and resistant filaria disease transmission

NASA Astrophysics Data System (ADS)

Fuady, A. M.; Nuraini, N.; Soewono, E.; Tasman, H.; Supriatna, A. K.

2014-03-01

It has been indicated that a long term application of combined mass drug treatment may contribute to the development of drug resistance in lymphatic filariasis. This phenomenon is not well understood due to the complexity of filaria life cycle. In this paper we formulate a mathematical model for the spread of mass drug resistant in a filaria endemic region. The model is represented in a 13-dimensional Host-Vector system. The basic reproductive ratio of the system which is obtained from the next generation matrix, and analysis of stability of both the disease free equilibrium and the coexistence equilibria are shown. Numerical simulation for long term dynamics for possible field conditions is also shown.

Impaired Attention in the 3xTgAD Model of Alzheimer’s Disease Assessed Using a Translational Touchscreen Method for Mice: Rescue by Donepezil (Aricept)

PubMed Central

Romberg, Carola; Mattson, Mark P.; Mughal, Mohamed R.; Bussey, Timothy J.; Saksida, Lisa M.

2011-01-01

Several mouse models of Alzheimer’s Disease (AD) with abundant β-amyloid and/or aberrantly phosphorylated tau develop memory impairments. However, multiple non-mnemonic cognitive domains such as attention and executive control are also compromised early in AD individuals. Currently, it is unclear whether mutations in the β-amyloid precursor protein (APP) and tau are sufficient to cause similar, AD-like attention deficits in mouse models of the disease. To address this question, we tested 3xTgAD mice (which express APPswe, PS1M146V and tauP301L mutations) and wild type control mice on a newly-developed touchscreen-based 5-choice serial reaction time test of attention and response control. The 3xTgAD mice attended less accurately to short, spatially unpredictable stimuli when the attentional demand of the task was high, and also showed a general tendency to make more perseverative responses than wild type mice. The attentional impairment of 3xTgAD mice was comparable to that of AD patients in two aspects; first, although 3xTgAD mice initially responded as accurately as wild type mice, they subsequently failed to sustain their attention over the duration of the task; second, the ability to sustain attention was enhanced by the cholinesterase inhibitor donepezil (Aricept). These findings demonstrate that familial AD mutations not only affect memory, but also cause significant impairments in attention, a cognitive domain supported by the prefrontal cortex and its afferents. Because attention deficits are likely to affect memory encoding and other cognitive abilities, our findings have important consequences for the assessment of disease mechanisms and therapeutics in animal models of AD. PMID:21368062

Adding a solar-radiance function to the Hošek-Wilkie skylight model.

PubMed

Hošek, Lukáš; Wilkie, Alexander

2013-01-01

One prerequisite for realistic renderings of outdoor scenes is the proper capturing of the sky's appearance. Currently, an explicit simulation of light scattering in the atmosphere isn't computationally feasible, and won't be in the foreseeable future. Captured luminance patterns have proven their usefulness in practice but can't meet all user needs. To fill this capability gap, computer graphics technology has employed analytical models of sky-dome luminance patterns for more than two decades. For technical reasons, such models deal with only the sky dome's appearance, though, and exclude the solar disc. The widely used model proposed by Arcot Preetham and colleagues employed a separately derived analytical formula for adding a solar emitter of suitable radiant intensity. Although this yields reasonable results, the formula is derived in a manner that doesn't exactly match the conditions in their sky-dome model. But the more sophisticated a skylight model is and the more subtly it can represent different conditions, the more the solar radiance should exactly match the skylight's conditions. Toward that end, researchers propose a solar-radiance function that exactly matches a recently published high-quality analytical skylight model.

Large-N solution of the heterotic CP(N-1) model with twisted masses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bolokhov, Pavel A.; Department of Physics and Astronomy, University of Victoria, Victoria, BC, V8P 1A1; Shifman, Mikhail

2010-07-15

We address a number of unanswered questions in the N=(0,2)-deformed CP(N-1) model with twisted masses. In particular, we complete the program of solving the CP(N-1) model with twisted masses in the large-N limit. In A. Gorsky, M. Shifman, and A. Yung, Phys. Rev. D 73, 065011 (2006), a nonsupersymmetric version of the model with the Z{sub N} symmetric twisted masses was analyzed in the framework of Witten's method. In M. Shifman and A. Yung, Phys. Rev. D 77, 125017 (2008), this analysis was extended: the large-N solution of the heterotic N=(0,2) CP(N-1) model with no twisted masses was found. Heremore » we solve this model with the twisted masses switched on. Dynamical scenarios at large and small m are studied (m is the twisted-mass scale). We found three distinct phases and two phase transitions on the m plane. Two phases with the spontaneously broken Z{sub N} symmetry are separated by a phase with unbroken Z{sub N}. This latter phase is characterized by a unique vacuum and confinement of all U(1) charged fields (''quarks''). In the broken phases (one of them is at strong coupling) there are N degenerate vacua and no confinement, similarly to the situation in the N=(2,2) model. Supersymmetry is spontaneously broken everywhere except a circle |m|={Lambda} in the Z{sub N}-unbroken phase. Related issues are considered. In particular, we discuss the mirror representation for the heterotic model in a certain limiting case.« less

The Mass Distribution of Stellar-mass Black Holes

NASA Astrophysics Data System (ADS)

Farr, Will M.; Sravan, Niharika; Cantrell, Andrew; Kreidberg, Laura; Bailyn, Charles D.; Mandel, Ilya; Kalogera, Vicky

2011-11-01

We perform a Bayesian analysis of the mass distribution of stellar-mass black holes using the observed masses of 15 low-mass X-ray binary systems undergoing Roche lobe overflow and 5 high-mass, wind-fed X-ray binary systems. Using Markov Chain Monte Carlo calculations, we model the mass distribution both parametrically—as a power law, exponential, Gaussian, combination of two Gaussians, or log-normal distribution—and non-parametrically—as histograms with varying numbers of bins. We provide confidence bounds on the shape of the mass distribution in the context of each model and compare the models with each other by calculating their relative Bayesian evidence as supported by the measurements, taking into account the number of degrees of freedom of each model. The mass distribution of the low-mass systems is best fit by a power law, while the distribution of the combined sample is best fit by the exponential model. This difference indicates that the low-mass subsample is not consistent with being drawn from the distribution of the combined population. We examine the existence of a "gap" between the most massive neutron stars and the least massive black holes by considering the value, M 1%, of the 1% quantile from each black hole mass distribution as the lower bound of black hole masses. Our analysis generates posterior distributions for M 1%; the best model (the power law) fitted to the low-mass systems has a distribution of lower bounds with M 1%>4.3 M sun with 90% confidence, while the best model (the exponential) fitted to all 20 systems has M 1%>4.5 M sun with 90% confidence. We conclude that our sample of black hole masses provides strong evidence of a gap between the maximum neutron star mass and the lower bound on black hole masses. Our results on the low-mass sample are in qualitative agreement with those of Ozel et al., although our broad model selection analysis more reliably reveals the best-fit quantitative description of the underlying mass

A mass balance model to estimate the rate of composting, methane oxidation and anaerobic digestion in soil covers and shallow waste layers.

PubMed

Rafiee, Reza; Obersky, Lizanne; Xie, Sihuang; Clarke, William P

2017-05-01

Although CH 4 oxidation in landfill soil covers is widely studied, the extent of composting and CH 4 oxidation in underlying waste layers has been speculated but not measured. The objective of this study was to develop and validate a mass balance model to estimate the simultaneous rates of anaerobic digestion (r AD ), CH 4 oxidation (r OX ) and composting (r COM ) in environments where O 2 penetration is variable and zones of aerobic and anaerobic activity are intermingled. The modelled domain could include, as an example, a soil cover and the underlying shallow waste to a nominated depth. The proposed model was demonstrated on a blend of biogas from three separate known sources of gas representing the three reaction processes: (i) a bottle of laboratory grade 50:50% CH 4 :CO 2 gas representing anaerobic digestion biogas; (ii) an aerated 250mL bottle containing food waste that represented composting activity; and (iii) an aerated 250mL bottle containing non-degradable graphite granules inoculated with methanotrophs and incubated with CH 4 and O 2 to represent methanotrophic activity. CO 2 , CH 4 , O 2 and the stable isotope 13 C-CO 2 were chosen as the components for the mass balance model. The three reaction rates, r (=r AD , r OX , r COM ) were calculated as fitting parameters to the overdetermined set of 4mass balance equations with the net flux of these components from the bottles q (= [Formula: see text] , [Formula: see text] , [Formula: see text] and [Formula: see text] ) as inputs to the model. The coefficient of determination (r 2 ) for observed versus modelled values of r were 1.00, 0.97, 0.98 when the stoichiometry of each reaction was based on gas yields measured in the individual bottles and q was calculated by summing yields from the three bottles. r 2 deteriorated to 0.95, 0.96, 0.87 when using an average stoichiometry from 11 incubations of each of the composting and methane oxidation processes. The significant deterioration in the estimation of r

Homeostasis Model Assessment-Adiponectin: the role of different types of physical exercise in obese adolescents.

PubMed

da Silveira Campos, Raquel M; Landi Masquio, Deborah C; Campos Corgosinho, Flávia; de Lima Sanches, Priscila; de Piano, Aline; Carnier, June; Leão da Silva, Patrícia; Grotti Clemente, Ana P; de Castro Ferreira Vicente, Sofia E; Oyama, Lila M; da Penha Oller do Nascimento, Claudia M; Tock, Lian; Tufik, Sergio; de Mello, Marco T; Dâmaso, Ana R

2017-06-01

Homeostasis Model Assessment-Adiponectin (HOMA-AD) is suggesting a new biomarker of insulin resistance in obese population. In this way, the purpose of this study was to investigate the effects of different kinds of exercise in the sensitive index predictor of insulin resistance. A total of 148 obese adolescents were enrolled in the program. They aged 15-19 y, with Body Mass Index (BMI) ≥P95th and were submitted to 1 year of interdisciplinary weight loss therapy, randomized in two groups, aerobic training (AT) (N.=51) and aerobic plus resistance training (N.=97). Blood samples were collected to analyze adiponectin, glucose and insulin concentrations. The insulin resistance was measured by HOMA-AD and Homeostasis Model Assessment Insulin Resistance Index (HOMA-IR). Both kinds of exercise training promoted a decrease in body mass, body mass index, fat mass, visceral and subcutaneous fat. However, only aerobic plus resistance training was effective to reduce HOMA-AD, insulin and glucose concentration; and increase insulin sensibility and adiponectin concentration. The aerobic plus resistance training was more effective than AT alone to improve the HOMA-AD, suggesting clinical application on obesity, diabetes, atherosclerosis and metabolic syndrome control in the pediatric population.

An equivalent viscoelastic model for rock mass with parallel joints

NASA Astrophysics Data System (ADS)

Li, Jianchun; Ma, Guowei; Zhao, Jian

2010-03-01

An equivalent viscoelastic medium model is proposed for rock mass with parallel joints. A concept of "virtual wave source (VWS)" is proposed to take into account the wave reflections between the joints. The equivalent model can be effectively applied to analyze longitudinal wave propagation through discontinuous media with parallel joints. Parameters in the equivalent viscoelastic model are derived analytically based on longitudinal wave propagation across a single rock joint. The proposed model is then verified by applying identical incident waves to the discontinuous and equivalent viscoelastic media at one end to compare the output waves at the other end. When the wavelength of the incident wave is sufficiently long compared to the joint spacing, the effect of the VWS on wave propagation in rock mass is prominent. The results from the equivalent viscoelastic medium model are very similar to those determined from the displacement discontinuity method. Frequency dependence and joint spacing effect on the equivalent viscoelastic model and the VWS method are discussed.

Neutrino mass model with S3 symmetry and seesaw interplay

NASA Astrophysics Data System (ADS)

Pramanick, Soumita; Raychaudhuri, Amitava

2016-12-01

We develop a seesaw model for neutrino masses and mixing with an S3×Z3 symmetry. It involves an interplay of type-I and type-II seesaw contributions of which the former is subdominant. The S3×Z3 quantum numbers of the fermion and scalar fields are chosen such that the type-II seesaw generates a mass matrix which incorporates the atmospheric mass splitting and sets θ23=π /4 . The solar splitting and θ13 are absent, while the third mixing angle can achieve any value, θ120. Specific choices of θ120 are of interest, e.g., 35.3° (tribimaximal), 45.0° (bimaximal), 31.7° (golden ratio), and 0° (no solar mixing). The role of the type-I seesaw is to nudge all the above into the range indicated by the data. The model results in novel interrelationships between these quantities due to their common origin, making it readily falsifiable. For example, normal (inverted) ordering is associated with θ23 in the first (second) octant. C P violation is controlled by phases in the right-handed neutrino Majorana mass matrix, Mν R . In their absence, only normal ordering is admissible. When Mν R is complex, the Dirac C P phase, δ , can be large, i.e., ˜±π /2 , and inverted ordering is also allowed. The preliminary results from T2K and NOVA which favor normal ordering and δ ˜-π /2 are indicative, in this model, of a lightest neutrino mass of 0.05 eV or more.

Using semantic data modeling techniques to organize an object-oriented database for extending the mass storage model

NASA Technical Reports Server (NTRS)

Campbell, William J.; Short, Nicholas M., Jr.; Roelofs, Larry H.; Dorfman, Erik

1991-01-01

A methodology for optimizing organization of data obtained by NASA earth and space missions is discussed. The methodology uses a concept based on semantic data modeling techniques implemented in a hierarchical storage model. The modeling is used to organize objects in mass storage devices, relational database systems, and object-oriented databases. The semantic data modeling at the metadata record level is examined, including the simulation of a knowledge base and semantic metadata storage issues. The semantic data model hierarchy and its application for efficient data storage is addressed, as is the mapping of the application structure to the mass storage.

Calibration of mass transfer-based models to predict reference crop evapotranspiration

NASA Astrophysics Data System (ADS)

Valipour, Mohammad

2017-05-01

The present study aims to compare mass transfer-based models to determine the best model under different weather conditions. The results showed that the Penman model estimates reference crop evapotranspiration better than other models in most provinces of Iran (15 provinces). However, the values of R 2 were less than 0.90 for 24 provinces of Iran. Therefore, the models were calibrated, and precision of estimation was increased (the values of R 2 were less than 0.90 for only ten provinces in the modified models). The mass transfer-based models estimated reference crop evapotranspiration in the northern (near the Caspian Sea) and southern (near the Persian Gulf) Iran (annual relative humidity more than 65 %) better than other provinces. The best values of R 2 were 0.96 and 0.98 for the Trabert and Rohwer models in Ardabil (AR) and Mazandaran (MZ) provinces before and after calibration, respectively. Finally, a list of the best performances of each model was presented to use other regions and next studies according to values of mean, maximum, and minimum temperature, relative humidity, and wind speed. The best weather conditions to use mass transfer-based equations are 8-18 °C (with the exception of Ivanov), <25.5 °C, <15 °C, >55 % for mean, maximum, and minimum temperature, and relative humidity, respectively.

Mathematical Models for the Apparent Mass of the Seated Human Body Exposed to Vertical Vibration

NASA Astrophysics Data System (ADS)

Wei, L.; Griffin, M. J.

1998-05-01

Alternative mathematical models of the vertical apparent mass of the seated human body are developed. The optimum parameters of four models (two single-degree-of-freedom models and two two-degree-of-freedom models) are derived from the mean measured apparent masses of 60 subjects (24 men, 24 women, 12 children) previously reported. The best fits were obtained by fitting the phase data with single-degree-of-freedom and two-degree-of-freedom models having rigid support structures. For these two models, curve fitting was performed on each of the 60 subjects (so as to obtain optimum model parameters for each subject), for the averages of each of the three groups of subjects, and for the entire group of subjects. The values obtained are tabulated. Use of a two-degree-of-freedom model provided a better fit to the phase of the apparent mass at frequencies greater than about 8 Hz and an improved fit to the modulus of the apparent mass at frequencies around 5 Hz. It is concluded that the two-degree-of-freedom model provides an apparent mass similar to that of the human body, but this does not imply that the body moves in the same manner as the masses in this optimized two-degree-of-freedom model.

Glottal flow through a two-mass model: comparison of Navier-Stokes solutions with simplified models.

PubMed

de Vries, M P; Schutte, H K; Veldman, A E P; Verkerke, G J

2002-04-01

A new numerical model of the vocal folds is presented based on the well-known two-mass models of the vocal folds. The two-mass model is coupled to a model of glottal airflow based on the incompressible Navier-Stokes equations. Glottal waves are produced using different initial glottal gaps and different subglottal pressures. Fundamental frequency, glottal peak flow, and closed phase of the glottal waves have been compared with values known from the literature. The phonation threshold pressure was determined for different initial glottal gaps. The phonation threshold pressure obtained using the flow model with Navier-Stokes equations corresponds better to values determined in normal phonation than the phonation threshold pressure obtained using the flow model based on the Bernoulli equation. Using the Navier-Stokes equations, an increase of the subglottal pressure causes the fundamental frequency and the glottal peak flow to increase, whereas the fundamental frequency in the Bernoulli-based model does not change with increasing pressure.

Vocabulary and Experiences to Develop a Center of Mass Model

ERIC Educational Resources Information Center

Kaar, Taylor; Pollack, Linda B.; Lerner, Michael E.; Engels, Robert J.

2017-01-01

The use of systems in many introductory courses is limited and often implicit. Modeling two or more objects as a system and tracking the center of mass of that system is usually not included. Thinking in terms of the center of mass facilitates problem solving while exposing the importance of using conservation laws. We present below three…

A mass-density model can account for the size-weight illusion

PubMed Central

Bergmann Tiest, Wouter M.; Drewing, Knut

2018-01-01

When judging the heaviness of two objects with equal mass, people perceive the smaller and denser of the two as being heavier. Despite the large number of theories, covering bottom-up and top-down approaches, none of them can fully account for all aspects of this size-weight illusion and thus for human heaviness perception. Here we propose a new maximum-likelihood estimation model which describes the illusion as the weighted average of two heaviness estimates with correlated noise: One estimate derived from the object’s mass, and the other from the object’s density, with estimates’ weights based on their relative reliabilities. While information about mass can directly be perceived, information about density will in some cases first have to be derived from mass and volume. However, according to our model at the crucial perceptual level, heaviness judgments will be biased by the objects’ density, not by its size. In two magnitude estimation experiments, we tested model predictions for the visual and the haptic size-weight illusion. Participants lifted objects which varied in mass and density. We additionally varied the reliability of the density estimate by varying the quality of either visual (Experiment 1) or haptic (Experiment 2) volume information. As predicted, with increasing quality of volume information, heaviness judgments were increasingly biased towards the object’s density: Objects of the same density were perceived as more similar and big objects were perceived as increasingly lighter than small (denser) objects of the same mass. This perceived difference increased with an increasing difference in density. In an additional two-alternative forced choice heaviness experiment, we replicated that the illusion strength increased with the quality of volume information (Experiment 3). Overall, the results highly corroborate our model, which seems promising as a starting point for a unifying framework for the size-weight illusion and human heaviness

A mass-density model can account for the size-weight illusion.

PubMed

Wolf, Christian; Bergmann Tiest, Wouter M; Drewing, Knut

2018-01-01

When judging the heaviness of two objects with equal mass, people perceive the smaller and denser of the two as being heavier. Despite the large number of theories, covering bottom-up and top-down approaches, none of them can fully account for all aspects of this size-weight illusion and thus for human heaviness perception. Here we propose a new maximum-likelihood estimation model which describes the illusion as the weighted average of two heaviness estimates with correlated noise: One estimate derived from the object's mass, and the other from the object's density, with estimates' weights based on their relative reliabilities. While information about mass can directly be perceived, information about density will in some cases first have to be derived from mass and volume. However, according to our model at the crucial perceptual level, heaviness judgments will be biased by the objects' density, not by its size. In two magnitude estimation experiments, we tested model predictions for the visual and the haptic size-weight illusion. Participants lifted objects which varied in mass and density. We additionally varied the reliability of the density estimate by varying the quality of either visual (Experiment 1) or haptic (Experiment 2) volume information. As predicted, with increasing quality of volume information, heaviness judgments were increasingly biased towards the object's density: Objects of the same density were perceived as more similar and big objects were perceived as increasingly lighter than small (denser) objects of the same mass. This perceived difference increased with an increasing difference in density. In an additional two-alternative forced choice heaviness experiment, we replicated that the illusion strength increased with the quality of volume information (Experiment 3). Overall, the results highly corroborate our model, which seems promising as a starting point for a unifying framework for the size-weight illusion and human heaviness perception.

Designing added functions in engineered cementitious composites

NASA Astrophysics Data System (ADS)

Yang, En-Hua

In this dissertation, a new and systematic material design approach is developed for ECC with added functions through material microstructures linkage to composite macroscopic behavior. The thesis research embodies theoretical development by building on previous ECC micromechanical models, and experimental investigations into three specific new versions of ECC with added functions aimed at addressing societal demands of our built infrastructure. Specifically, the theoretical study includes three important ECC modeling elements: Steady-state crack propagation analyses and simulation, predictive accuracy of the fiber bridging constitutive model, and development of the rate-dependent strain-hardening criteria. The first element establishes the steady-state cracking criterion as a fundamental requirement for multiple cracking behavior in brittle matrix composites. The second element improves the accuracy of crack-width prediction in ECC. The third element establishes the micromechanics basis for impact-resistant ECC design. Three new ECCs with added functions were developed and experimentally verified in this thesis research through the enhanced theoretical framework. A green ECC incorporating a large volume of industrial waste was demonstrated to possess reduced crack width and drying shrinkage. The self-healing ECC designed with tight crack width was demonstrated to recover transport and mechanical properties after microcrack damage when exposed to wet and dry cycles. The impact-resistant ECC was demonstrated to retain tensile ductility with increased strength under moderately high strain-rate loading. These new versions of ECC with added functions are expected to contribute greatly to enhancing the sustainability, durability, and safety of civil infrastructure built with ECC. This research establishes the effectiveness of micromechanics-based design and material ingredient tailoring for ECC with added new attributes but without losing its basic tensile ductile

Consumption of Mass Communication--Construction of a Model on Information Consumption Behaviour.

ERIC Educational Resources Information Center

Sepstrup, Preben

A general conceptual model on the consumption of information is introduced. Information as the output of the mass media is treated as a product, and a model on the consumption of this product is developed by merging elements from consumer behavior theory and mass communication theory. Chapter I gives basic assumptions about the individual and the…

THE SYSTEMATICS OF STRONG LENS MODELING QUANTIFIED: THE EFFECTS OF CONSTRAINT SELECTION AND REDSHIFT INFORMATION ON MAGNIFICATION, MASS, AND MULTIPLE IMAGE PREDICTABILITY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Traci L.; Sharon, Keren, E-mail: tljohn@umich.edu

Until now, systematic errors in strong gravitational lens modeling have been acknowledged but have never been fully quantified. Here, we launch an investigation into the systematics induced by constraint selection. We model the simulated cluster Ares 362 times using random selections of image systems with and without spectroscopic redshifts and quantify the systematics using several diagnostics: image predictability, accuracy of model-predicted redshifts, enclosed mass, and magnification. We find that for models with >15 image systems, the image plane rms does not decrease significantly when more systems are added; however, the rms values quoted in the literature may be misleading asmore » to the ability of a model to predict new multiple images. The mass is well constrained near the Einstein radius in all cases, and systematic error drops to <2% for models using >10 image systems. Magnification errors are smallest along the straight portions of the critical curve, and the value of the magnification is systematically lower near curved portions. For >15 systems, the systematic error on magnification is ∼2%. We report no trend in magnification error with the fraction of spectroscopic image systems when selecting constraints at random; however, when using the same selection of constraints, increasing this fraction up to ∼0.5 will increase model accuracy. The results suggest that the selection of constraints, rather than quantity alone, determines the accuracy of the magnification. We note that spectroscopic follow-up of at least a few image systems is crucial because models without any spectroscopic redshifts are inaccurate across all of our diagnostics.« less

The Systematics of Strong Lens Modeling Quantified: The Effects of Constraint Selection and Redshift Information on Magnification, Mass, and Multiple Image Predictability

NASA Astrophysics Data System (ADS)

Johnson, Traci L.; Sharon, Keren

2016-11-01

Until now, systematic errors in strong gravitational lens modeling have been acknowledged but have never been fully quantified. Here, we launch an investigation into the systematics induced by constraint selection. We model the simulated cluster Ares 362 times using random selections of image systems with and without spectroscopic redshifts and quantify the systematics using several diagnostics: image predictability, accuracy of model-predicted redshifts, enclosed mass, and magnification. We find that for models with >15 image systems, the image plane rms does not decrease significantly when more systems are added; however, the rms values quoted in the literature may be misleading as to the ability of a model to predict new multiple images. The mass is well constrained near the Einstein radius in all cases, and systematic error drops to <2% for models using >10 image systems. Magnification errors are smallest along the straight portions of the critical curve, and the value of the magnification is systematically lower near curved portions. For >15 systems, the systematic error on magnification is ∼2%. We report no trend in magnification error with the fraction of spectroscopic image systems when selecting constraints at random; however, when using the same selection of constraints, increasing this fraction up to ∼0.5 will increase model accuracy. The results suggest that the selection of constraints, rather than quantity alone, determines the accuracy of the magnification. We note that spectroscopic follow-up of at least a few image systems is crucial because models without any spectroscopic redshifts are inaccurate across all of our diagnostics.

A mass transfer model of ammonia volatilization from anaerobic digestate.

PubMed

Whelan, M J; Everitt, T; Villa, R

2010-10-01

Anaerobic digestion (AD) is becoming increasingly popular for treating organic waste. The methane produced can be burned to generate electricity and the digestate, which is high in mineral nitrogen, can be used as a fertiliser. In this paper we evaluate potential losses of ammonia via volatilization from food waste anaerobic digestate using a closed chamber system equipped with a sulphuric acid trap. Ammonia losses represent a pollution source and, over long periods could reduce the agronomic value of the digestate. Observed ammonia losses from the experimental system were linear with time. A simple non-steady-state partitioning model was developed to represent the process. After calibration, the model was able to describe the behaviour of ammonia in the digestate and in the trap very well. The average rate of volatilization was approximately 5.2 g Nm(-2)week(-1). The model was used to extrapolate the findings of the laboratory study to a number of AD storage scenarios. The simulations highlight that open storage of digestate could result in significant losses of ammonia to the atmosphere. Losses are predicted to be relatively minor from covered facilities, particularly if depth to surface area ratio is high. (c) 2009 Elsevier Ltd. All rights reserved.

Estimating Mass Properties of Dinosaurs Using Laser Imaging and 3D Computer Modelling

PubMed Central

Bates, Karl T.; Manning, Phillip L.; Hodgetts, David; Sellers, William I.

2009-01-01

Body mass reconstructions of extinct vertebrates are most robust when complete to near-complete skeletons allow the reconstruction of either physical or digital models. Digital models are most efficient in terms of time and cost, and provide the facility to infinitely modify model properties non-destructively, such that sensitivity analyses can be conducted to quantify the effect of the many unknown parameters involved in reconstructions of extinct animals. In this study we use laser scanning (LiDAR) and computer modelling methods to create a range of 3D mass models of five specimens of non-avian dinosaur; two near-complete specimens of Tyrannosaurus rex, the most complete specimens of Acrocanthosaurus atokensis and Strutiomimum sedens, and a near-complete skeleton of a sub-adult Edmontosaurus annectens. LiDAR scanning allows a full mounted skeleton to be imaged resulting in a detailed 3D model in which each bone retains its spatial position and articulation. This provides a high resolution skeletal framework around which the body cavity and internal organs such as lungs and air sacs can be reconstructed. This has allowed calculation of body segment masses, centres of mass and moments or inertia for each animal. However, any soft tissue reconstruction of an extinct taxon inevitably represents a best estimate model with an unknown level of accuracy. We have therefore conducted an extensive sensitivity analysis in which the volumes of body segments and respiratory organs were varied in an attempt to constrain the likely maximum plausible range of mass parameters for each animal. Our results provide wide ranges in actual mass and inertial values, emphasizing the high level of uncertainty inevitable in such reconstructions. However, our sensitivity analysis consistently places the centre of mass well below and in front of hip joint in each animal, regardless of the chosen combination of body and respiratory structure volumes. These results emphasize that future

Estimating mass properties of dinosaurs using laser imaging and 3D computer modelling.

PubMed

Bates, Karl T; Manning, Phillip L; Hodgetts, David; Sellers, William I

2009-01-01

Body mass reconstructions of extinct vertebrates are most robust when complete to near-complete skeletons allow the reconstruction of either physical or digital models. Digital models are most efficient in terms of time and cost, and provide the facility to infinitely modify model properties non-destructively, such that sensitivity analyses can be conducted to quantify the effect of the many unknown parameters involved in reconstructions of extinct animals. In this study we use laser scanning (LiDAR) and computer modelling methods to create a range of 3D mass models of five specimens of non-avian dinosaur; two near-complete specimens of Tyrannosaurus rex, the most complete specimens of Acrocanthosaurus atokensis and Strutiomimum sedens, and a near-complete skeleton of a sub-adult Edmontosaurus annectens. LiDAR scanning allows a full mounted skeleton to be imaged resulting in a detailed 3D model in which each bone retains its spatial position and articulation. This provides a high resolution skeletal framework around which the body cavity and internal organs such as lungs and air sacs can be reconstructed. This has allowed calculation of body segment masses, centres of mass and moments or inertia for each animal. However, any soft tissue reconstruction of an extinct taxon inevitably represents a best estimate model with an unknown level of accuracy. We have therefore conducted an extensive sensitivity analysis in which the volumes of body segments and respiratory organs were varied in an attempt to constrain the likely maximum plausible range of mass parameters for each animal. Our results provide wide ranges in actual mass and inertial values, emphasizing the high level of uncertainty inevitable in such reconstructions. However, our sensitivity analysis consistently places the centre of mass well below and in front of hip joint in each animal, regardless of the chosen combination of body and respiratory structure volumes. These results emphasize that future

Modelling river bank erosion processes and mass failure mechanisms using 2-D depth averaged numerical model

NASA Astrophysics Data System (ADS)

Die Moran, Andres; El kadi Abderrezzak, Kamal; Tassi, Pablo; Herouvet, Jean-Michel

2014-05-01

Bank erosion is a key process that may cause a large number of economic and environmental problems (e.g. land loss, damage to structures and aquatic habitat). Stream bank erosion (toe erosion and mass failure) represents an important form of channel morphology changes and a significant source of sediment. With the advances made in computational techniques, two-dimensional (2-D) numerical models have become valuable tools for investigating flow and sediment transport in open channels at large temporal and spatial scales. However, the implementation of mass failure process in 2D numerical models is still a challenging task. In this paper, a simple, innovative algorithm is implemented in the Telemac-Mascaret modeling platform to handle bank failure: failure occurs whether the actual slope of one given bed element is higher than the internal friction angle. The unstable bed elements are rotated around an appropriate axis, ensuring mass conservation. Mass failure of a bank due to slope instability is applied at the end of each sediment transport evolution iteration, once the bed evolution due to bed load (and/or suspended load) has been computed, but before the global sediment mass balance is verified. This bank failure algorithm is successfully tested using two laboratory experimental cases. Then, bank failure in a 1:40 scale physical model of the Rhine River composed of non-uniform material is simulated. The main features of the bank erosion and failure are correctly reproduced in the numerical simulations, namely the mass wasting at the bank toe, followed by failure at the bank head, and subsequent transport of the mobilised material in an aggradation front. Volumes of eroded material obtained are of the same order of magnitude as the volumes measured during the laboratory tests.

Sex-Based Differences in Adélie Penguin (Pygoscelis adeliae) Chick Growth Rates and Diet.

PubMed

Jennings, Scott; Varsani, Arvind; Dugger, Katie M; Ballard, Grant; Ainley, David G

2016-01-01

Sexually size-dimorphic species must show some difference between the sexes in growth rate and/or length of growing period. Such differences in growth parameters can cause the sexes to be impacted by environmental variability in different ways, and understanding these differences allows a better understanding of patterns in productivity between individuals and populations. We investigated differences in growth rate and diet between male and female Adélie Penguin (Pygoscelis adeliae) chicks during two breeding seasons at Cape Crozier, Ross Island, Antarctica. Adélie Penguins are a slightly dimorphic species, with adult males averaging larger than adult females in mass (~11%) as well as bill (~8%) and flipper length (~3%). We measured mass and length of flipper, bill, tibiotarsus, and foot at 5-day intervals for 45 male and 40 female individually-marked chicks. Chick sex was molecularly determined from feathers. We used linear mixed effects models to estimate daily growth rate as a function of chick sex, while controlling for hatching order, brood size, year, and potential variation in breeding quality between pairs of parents. Accounting for season and hatching order, male chicks gained mass an average of 15.6 g d(-1) faster than females. Similarly, growth in bill length was faster for males, and the calculated bill size difference at fledging was similar to that observed in adults. There was no evidence for sex-based differences in growth of other morphological features. Adélie diet at Ross Island is composed almost entirely of two species--one krill (Euphausia crystallorophias) and one fish (Pleuragramma antarctica), with fish having a higher caloric value. Using isotopic analyses of feather samples, we also determined that male chicks were fed a higher proportion of fish than female chicks. The related differences in provisioning and growth rates of male and female offspring provides a greater understanding of the ways in which ecological factors may impact

Sex-Based Differences in Adélie Penguin (Pygoscelis adeliae) Chick Growth Rates and Diet

PubMed Central

Jennings, Scott; Varsani, Arvind; Dugger, Katie M.; Ballard, Grant; Ainley, David G.

2016-01-01

Sexually size-dimorphic species must show some difference between the sexes in growth rate and/or length of growing period. Such differences in growth parameters can cause the sexes to be impacted by environmental variability in different ways, and understanding these differences allows a better understanding of patterns in productivity between individuals and populations. We investigated differences in growth rate and diet between male and female Adélie Penguin (Pygoscelis adeliae) chicks during two breeding seasons at Cape Crozier, Ross Island, Antarctica. Adélie Penguins are a slightly dimorphic species, with adult males averaging larger than adult females in mass (~11%) as well as bill (~8%) and flipper length (~3%). We measured mass and length of flipper, bill, tibiotarsus, and foot at 5-day intervals for 45 male and 40 female individually-marked chicks. Chick sex was molecularly determined from feathers. We used linear mixed effects models to estimate daily growth rate as a function of chick sex, while controlling for hatching order, brood size, year, and potential variation in breeding quality between pairs of parents. Accounting for season and hatching order, male chicks gained mass an average of 15.6 g d-1 faster than females. Similarly, growth in bill length was faster for males, and the calculated bill size difference at fledging was similar to that observed in adults. There was no evidence for sex-based differences in growth of other morphological features. Adélie diet at Ross Island is composed almost entirely of two species—one krill (Euphausia crystallorophias) and one fish (Pleuragramma antarctica), with fish having a higher caloric value. Using isotopic analyses of feather samples, we also determined that male chicks were fed a higher proportion of fish than female chicks. The related differences in provisioning and growth rates of male and female offspring provides a greater understanding of the ways in which ecological factors may impact the

How One School Implements and Experiences Ohio's Value-Added Model: A Case Study

ERIC Educational Resources Information Center

Quattrochi, David

2009-01-01

Ohio made value-added law in 2003 and incorporated value-added assessment to its operating standards for teachers and administrators in 2006. Value-added data is used to determine if students are making a year's growth at the end of each school year. Schools and districts receive a rating of "Below Growth, Met Growth, or Above Growth" on…

Mathematical model of compact type evaporator

NASA Astrophysics Data System (ADS)

Borovička, Martin; Hyhlík, Tomáš

2018-06-01

In this paper, development of the mathematical model for evaporator used in heat pump circuits is covered, with focus on air dehumidification application. Main target of this ad-hoc numerical model is to simulate heat and mass transfer in evaporator for prescribed inlet conditions and different geometrical parameters. Simplified 2D mathematical model is developed in MATLAB SW. Solvers for multiple heat and mass transfer problems - plate surface temperature, condensate film temperature, local heat and mass transfer coefficients, refrigerant temperature distribution, humid air enthalpy change are included as subprocedures of this model. An automatic procedure of data transfer is developed in order to use results of MATLAB model in more complex simulation within commercial CFD code. In the end, Proper Orthogonal Decomposition (POD) method is introduced and implemented into MATLAB model.

What caused terrestrial dust loading and climate downturns between A.D. 533 and 540?

USGS Publications Warehouse

Abbott, Dallas H.; Breger, Dee; Biscaye, Pierre E.; Barron, John A.; Juhl, Robert A.; McCafferty, Patrick

2014-01-01

Sn-rich particles, Ni-rich particles, and cosmic spherules are found together at four discrete stratigraphic levels within the 362-360 m depth interval of the Greenland Ice Sheet Project 2 (GISP2) ice core (72.6°N, 38.5°W, elevation: 3203 m). Using a previously derived calendar-year time scale, these particles span a time of increased dust loading of Earth's atmosphere between A.D. 533 and 540. The Sn-rich and Ni-rich particles contain an average of 10–11 wt% C. Their high C contents coupled with local enrichments in the volatile elements I, Zn, Cu, and Xe suggest a cometary source for the dust. The late spring timing of extraterrestrial input best matches the Eta Aquarid meteor shower associated with comet 1P/Halley. An increased flux of cometary dust might explain a modest climate downturn in A.D. 533. Both cometary dust and volcanic sulfate probably contributed to the profound global dimming during A.D. 536 and 537 but may be insufficient sources of fine aerosols. We found tropical marine microfossils and aerosol-sized CaCO3 particles at the end A.D. 535–start A.D. 536 level that we attribute to a low-latitude explosion in the ocean. This additional source of dust is probably needed to explain the solar dimming during A.D. 536 and 537. Although there has been no extinction documented at A.D. 536, our results are relevant because mass extinctions may also have multiple drivers. Detailed examinations of fine particles at and near extinction horizons can help to determine the relative contributions of cosmic and volcanic drivers to mass extinctions.

CHEMICAL MASS BALANCE MODEL: EPA-CMB8.2

EPA Science Inventory

The Chemical Mass Balance (CMB) method has been a popular approach for receptor modeling of ambient air pollutants for over two decades. For the past few years the U.S. Environmental Protection Agency's Office of Research and Development (ORD) and Office of Air Quality Plannin...

Analysis of Critical Mass in Threshold Model of Diffusion

NASA Astrophysics Data System (ADS)

Kim, Jeehong; Hur, Wonchang; Kang, Suk-Ho

2012-04-01

Why does diffusion sometimes show cascade phenomena but at other times is impeded? In addressing this question, we considered a threshold model of diffusion, focusing on the formation of a critical mass, which enables diffusion to be self-sustaining. Performing an agent-based simulation, we found that the diffusion model produces only two outcomes: Almost perfect adoption or relatively few adoptions. In order to explain the difference, we considered the various properties of network structures and found that the manner in which thresholds are arrayed over a network is the most critical factor determining the size of a cascade. On the basis of the results, we derived a threshold arrangement method effective for generation of a critical mass and calculated the size required for perfect adoption.

Symmetries, holography, and quantum phase transition in two-dimensional dilaton AdS gravity

NASA Astrophysics Data System (ADS)

Cadoni, Mariano; Ciulu, Matteo; Tuveri, Matteo

2018-05-01

We revisit the Almheiri-Polchinski dilaton gravity model from a two-dimensional (2D) bulk perspective. We describe a peculiar feature of the model, namely the pattern of conformal symmetry breaking using bulk Killing vectors, a covariant definition of mass and the flow between different vacua of the theory. We show that the effect of the symmetry breaking is both the generation of an infrared scale (a mass gap) and to make local the Goldstone modes associated with the asymptotic symmetries of the 2D spacetime. In this way a nonvanishing central charge is generated in the dual conformal theory, which accounts for the microscopic entropy of the 2D black hole. The use of covariant mass allows to compare energetically the two different vacua of the theory and to show that at zero temperature the vacuum with a constant dilaton is energetically preferred. We also translate in the bulk language several features of the dual CFT discussed by Maldacena et al. The uplifting of the 2D model to (d +2 )-dimensional theories exhibiting hyperscaling violation is briefly discussed.

Supersymmetry searches in GUT models with non-universal scalar masses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cannoni, M.; Gómez, M.E.; Ellis, J.

2016-03-01

We study SO(10), SU(5) and flipped SU(5) GUT models with non-universal soft supersymmetry-breaking scalar masses, exploring how they are constrained by LHC supersymmetry searches and cold dark matter experiments, and how they can be probed and distinguished in future experiments. We find characteristic differences between the various GUT scenarios, particularly in the coannihilation region, which is very sensitive to changes of parameters. For example, the flipped SU(5) GUT predicts the possibility of ∼t{sub 1}−χ coannihilation, which is absent in the regions of the SO(10) and SU(5) GUT parameter spaces that we study. We use the relic density predictions in differentmore » models to determine upper bounds for the neutralino masses, and we find large differences between different GUT models in the sparticle spectra for the same LSP mass, leading to direct connections of distinctive possible experimental measurements with the structure of the GUT group. We find that future LHC searches for generic missing E{sub T}, charginos and stops will be able to constrain the different GUT models in complementary ways, as will the Xenon 1 ton and Darwin dark matter scattering experiments and future FERMI or CTA γ-ray searches.« less

Relationship between US Societal Fatality Risk per Vehicle Miles of Travel and Mass, for Individual Vehicle Models over Time (Model Year)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wenzel, Tom P.

This report presents a new approach to analyze the relationship between vehicle mass and risk: tracking fatality risk by vehicle model year and mass, for individual vehicle models. This approach is appealing as it greatly minimizes the influence of driver characteristics and behavior, and crash circumstances, on fatality risk. However, only the most popular vehicle models, with the largest number of fatalities, can be analyzed in this manner. While the analysis of all vehicle models of a given type suggests that there is a relationship between increased mass and fatality risk, analysis of the ten most popular four-door car modelsmore » separately suggests that this relationship is weak: in many cases when the mass of a specific vehicle model is increased societal fatality risk is unchanged or even increases. These results suggest that increasing the mass of an individual vehicle model does not necessarily lead to decreased societal fatality risk.« less

AdS6 solutions of type II supergravity

NASA Astrophysics Data System (ADS)

Apruzzi, Fabio; Fazzi, Marco; Passias, Achilleas; Rosa, Dario; Tomasiello, Alessandro

2014-11-01

Very few AdS6 × M 4 supersymmetric solutions are known: one in massive IIA, and two IIB solutions dual to it. The IIA solution is known to be unique; in this paper, we use the pure spinor approach to give a classification for IIB supergravity. We reduce the problem to two PDEs on a two-dimensional space Σ. M 4 is then a fibration of S 2 over Σ; the metric and fluxes are completely determined in terms of the solution to the PDEs. The results seem likely to accommodate near-horizon limits of ( p, q)-fivebrane webs studied in the literature as a source of CFT5's. We also show that there are no AdS6 solutions in eleven-dimensional supergravity.

Quasilocal energy for three-dimensional massive gravity solutions with chiral deformations of AdS{sub 3} boundary conditions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garbarz, Alan, E-mail: alan-at@df.uba.ar; Giribet, Gaston, E-mail: gaston-at@df.uba.ar, E-mail: af.goya-at@df.uba.ar; Goya, Andrés, E-mail: gaston-at@df.uba.ar, E-mail: af.goya-at@df.uba.ar

2015-03-26

We consider critical gravity in three dimensions; that is, the New Massive Gravity theory formulated about Anti-de Sitter (AdS) space with the specific value of the graviton mass for which it results dual to a two-dimensional conformai field theory with vanishing central charge. As it happens with Kerr black holes in four-dimensional critical gravity, in three-dimensional critical gravity the Bañados-Teitelboim-Zanelli black holes have vanishing mass and vanishing angular momentum. However, provided suitable asymptotic conditions are chosen, the theory may also admit solutions carrying non-vanishing charges. Here, we give simple examples of exact solutions that exhibit falling-off conditions that are evenmore » weaker than those of the so-called Log-gravity. For such solutions, we define the quasilocal stress-tensor and use it to compute conserved charges. Despite the drastic deformation of AdS{sub 3} asymptotic, these solutions have finite mass and angular momentum, which are shown to be non-zero.« less

Nonequilibrium transition induced by mass media in a model for social influence

NASA Astrophysics Data System (ADS)

González-Avella, J. C.; Cosenza, M. G.; Tucci, K.

2005-12-01

We study the effect of mass media, modeled as an applied external field, on a social system based on Axelrod’s model for the dissemination of culture. The numerical simulations show that the system undergoes a nonequilibrium phase transition between an ordered phase (homogeneous culture) specified by the mass media and a disordered (culturally fragmented) one. The critical boundary separating these phases is calculated on the parameter space of the system, given by the intensity of the mass media influence and the number of options per cultural attribute. Counterintuitively, mass media can induce cultural diversity when its intensity is above some threshold value. The nature of the phase transition changes from continuous to discontinuous at some critical value of the number of options.

Discounting testimony with the argument ad hominem and a Bayesian congruent prior model.

PubMed

Bhatia, Jaydeep-Singh; Oaksford, Mike

2015-09-01

When directed to ignore evidence of a witness's previous bad character because of a violation of the rules of evidence, are jurors' beliefs still affected? The intuition is that they will be because in everyday argumentation, fallacies, like the ad hominem, are effective argumentative strategies. An ad hominem argument (against the person) undermines a conclusion by questioning the character of the proposer. This intuition divides current theories of argumentation. According to pragmadialectical theory (e.g., Van Eemeren & Grootendorst, 2004), procedural rules exactly like the rules of evidence are part of our cognitive resources for evaluating arguments. If one of these rules is violated, an argument should be treated as a fallacy and so it should not alter someone's belief in the conclusion. Some recent experiments investigating how reasonable these arguments are perceived to be seem to support this account (van Eemeren, Garssen, & Meuffels, 2009). These experiments are critiqued from the perspective of the relevance (Walton, 2009, 2010) and epistemic (Hahn & Oaksford, 2006, 2007; Oaksford & Hahn, 2004) approaches to argumentation. An experiment investigates the predictions of these approaches for a graded belief change version of van Eemeren et al.'s (2009) experiment, and the results are modeled using a Bayesian congruent prior model. These results cannot be explained by the pragmadialectical approach and show that in everyday argument people are extremely sensitive to the epistemic relevance of evidence. Moreover, it seems highly unlikely that this can be switched off in more formal contexts such as the courtroom. (c) 2015 APA, all rights reserved).

A climate simulation of the first millennium AD using a comprehensive Earth System Model

NASA Astrophysics Data System (ADS)

Wagner, Sebastian; Zorita, Eduardo

2014-05-01

Investigations of past climate using fully coupled comprehensive Earth System Models are restricted by the large computational costs of these simulations. Here we present first results from an on-going simulation with the MPI-ESM-P starting in year 100 BC. The simulation is forced with changes in orbital forcing and long-term solar variations augmented by a synthetic 11-year cycle including an interactive ozone cycle. For the first time also changes in volcanic activity are implemented based on the reconstruction method by Crowley and Unterman (2012). The basis of the extended volcanic forcing in terms of aerosol optical depth and effective radius are new sulfate estimations from ice cores from Greenland (NEEM) and Antarctica (WAIS) presented by Sigl et al. (2013). Because the NEEM record only reaches back as far as 79 AD, the time until 100 BC was filled by earlier information contained in the Dye 3 and GRIP record (Clausen et al., 1997). Compared to the 2nd millennium AD, the first millennium does however show a considerably reduced amount of large explosive tropical eruptions. On hemispheric and global scale the large outbreaks around the years 530 and 740 AD are well reflected as negative temperature anomalies. The 79 AD Vesuvius eruption does not however produce a pronounced hemispheric signal. The amount of sulphate ejected into the stratosphere may have been too low for a sustained hemispheric-scale cooling. The large eruption of 530 AD (so called 'mystic cloud') is however well reflected within the temperature evolution and is more pronounced over the northern hemisphere during summertime. On longer, multi-centennial, time scales, global temperatures show a slight decrease. This decrease is more pronounced over the NH hemisphere during JJA and is caused by the decline in the TOA short wave incoming radiation. Over the extratropical SH changes in orbital forcing are not reflected in temperature trends as clearly as over the NH due to the larger oceanic and

[Morphological analysis of the hippocampal region associated with an innate behaviour task in the transgenic mouse model (3xTg-AD) for Alzheimer disease].

PubMed

Orta-Salazar, E; Feria-Velasco, A; Medina-Aguirre, G I; Díaz-Cintra, S

2013-10-01

Different animal models for Alzheimer disease (AD) have been designed to support the hypothesis that the neurodegeneration (loss of neurons and synapses with reactive gliosis) associated with Aβ and tau deposition in these models is similar to that in the human brain. These alterations produce functional changes beginning with decreased ability to carry out daily and social life activities, memory loss, and neuropsychiatric disorders in general. Neuronal alteration plays an important role in early stages of the disease, especially in the CA1 area of hippocampus in both human and animal models. Two groups (WT and 3xTg-AD) of 11-month-old female mice were used in a behavioural analysis (nest building) and a morphometric analysis of the CA1 region of the dorsal hippocampus. The 3xTg-AD mice showed a 50% reduction in nest quality associated with a significant increase in damaged neurons in the CA1 hippocampal area (26%±6%, P<.05) compared to the WT group. The decreased ability to carry out activities of daily living (humans) or nest building (3xTg-AD mice) is related to the neuronal alterations observed in AD. These alterations are controlled by the hippocampus. Post-mortem analyses of the human hippocampus, and the CA1 region in 3xTg-AD mice, show that these areas are associated with alterations in the deposition of Aβ and tau proteins, which start accumulating in the early stages of AD. Copyright © 2013 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

Towards an Understanding of Physiological Body Mass Regulation: Seasonal Animal Models.

PubMed

Mercer, J G; Adam, C L; Morgan, P J

2000-01-01

This review is based around a number of interlinked hypotheses that can be summarised as follows: (i) mammalian body mass is regulated, (ii) the mechanisms that effect this regulation are common to all mammalian species, including humans, (iii) the neurochemical substrates involved in long term body mass regulation and in determining the level of body mass that will be defended may not be the same as those involved in short term energy homeostasis, or body mass defence, or may be differentially engaged, and (iv) "appropriate" body mass is encoded somewhere within the mammalian brain and acts as a comparator to influence both nutritional and reproductive physiology. These issues are of direct relevance to the epidemic of obesity in the Westernised human population and the poor success rate of conventional weight loss strategies. It is our contention that seasonal rodent models, and the Siberian hamster in particular, represent extremely valuable tools for the study of the mechanistic basis of body mass regulation. The Siberian hamster model is often perceived as an unusual mammalian variant that has evolved an almost counter-intuitive strategy for surviving periods of anticipated seasonal food shortage. However, there is compelling evidence that these animals are able to adjust their body mass continually and progressively according to their photoperiodic history, i.e. a seasonally-appropriate body mass. These adjustments to appropriate body mass are memorised even after the animals have been driven away from their normal body mass trajectory by imposed food restriction. Thus, photoperiod, acting through the pineal hormone, melatonin, is able to reset the desired body mass for a given time in the seasonal cycle. Importantly, daylength provides a tool to manipulate the body mass control system in an entirely physiological and stress-free manner. While resetting of body mass by photoperiod represents a level of control apparently confined to seasonal mammals, it has

Three phase heat and mass transfer model for unsaturated soil freezing process: Part 2 - model validation

NASA Astrophysics Data System (ADS)

Zhang, Yaning; Xu, Fei; Li, Bingxi; Kim, Yong-Song; Zhao, Wenke; Xie, Gongnan; Fu, Zhongbin

2018-04-01

This study aims to validate the three-phase heat and mass transfer model developed in the first part (Three phase heat and mass transfer model for unsaturated soil freezing process: Part 1 - model development). Experimental results from studies and experiments were used for the validation. The results showed that the correlation coefficients for the simulated and experimental water contents at different soil depths were between 0.83 and 0.92. The correlation coefficients for the simulated and experimental liquid water contents at different soil temperatures were between 0.95 and 0.99. With these high accuracies, the developed model can be well used to predict the water contents at different soil depths and temperatures.

[Value-Added--Adding Economic Value in the Food Industry].

ERIC Educational Resources Information Center

Welch, Mary A., Ed.

1989-01-01

This booklet focuses on the economic concept of "value added" to goods and services. A student activity worksheet illustrates how the steps involved in processing food are examples of the concept of value added. The booklet further links food processing to the idea of value added to the Gross National Product (GNP). Discussion questions,…