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Sample records for addition issues related

  1. Silage Additives and Management Issues

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Inoculants are the most common silage additives in the United States. These products contain lactic acid bacteria to supplement the lactic acid bacteria naturally on the crop and help insure a consistent fermentation in the silo. There are three types of inoculants: homofermentative lactic acid bact...

  2. Ethical Issues Related to Restructuring.

    ERIC Educational Resources Information Center

    Mielke, Patricia L.; Schuh, John H.

    1995-01-01

    Offers a framework for thinking about ethical principles through the use of codes of ethics. Examines the ethical issues of restructuring and discusses specific ethical dilemmas. Specifically outlines ethics related to resources allocation and management, and details critical points in restructuring. Argues that ethical guidelines help shape…

  3. Gender relations and economic issues.

    PubMed

    Elson, D

    1993-10-01

    While most discussions of economic issues pay no explicit attention to gender relations, most economic policy is marked by male bias which provides women with an unequal access to resources. This situation exists because most economists, officials, and business managers lack the imagination to see the gender impact of economic issues and most women's groups and researchers lack the language to portray this connection. This article explores some aspects of this gap and aims to provide women with the ability to effectively discuss economic issues. After an introduction, the article considers the basic problem caused by the fact that the economy is defined primarily in terms of money-making activities. This leads to a male bias since much of women's work occurs outside of the monetary sphere. The next section looks at how a failure to understand the significance of gender relations will interfere with the fulfillment of policy objectives. This discussion is followed by a description of how cutbacks in government expenditures increase the burden on women who must replace the services. Problems with the option of the private-sector replacing government services, such as the fact that increasing disposable income in households does not guarantee that unpaid labor will be reduced and the fact that the private sector may fail to expand in a productive way, are covered. The article then touches on the new emphasis placed by some economists and policy makers on cooperative and interactive solutions to these problems and ends by mentioning three new initiatives which seek to build capacity for gender-aware economic analysis: the development of a training program at Manchester University in the UK, coordination of an international research workshop by the University of Utah in the US, and development of an international association for feminist economics based in the US. PMID:12320735

  4. Myomas: anatomy and related issues.

    PubMed

    Tinelli, Andrea; Sparic, Radmila; Kadija, Saša; Babovic, Ivana; Tinelli, Raffaele; Mynbaev, Ospan A; Malvasi, Antonio

    2016-06-01

    Myomas are the most common disorder of the female genital organs, occurring more frequently throughout women's reproductive years. Myomas are a major health issue all over the world. They develop as a monoclonal tumor from cells influenced by ovarian steroids, and mediated by surrounding myometrial cells by paracrine mechanisms. During its growth, a myoma compresses the surrounding tissue, causing the formation of a pseudocapsule, encapsulating the myoma. The mechanical properties of myomas are a key factor which can contribute to their growth. While myomas are essentially rigid, their pseudocapsule is more elastic, and this allows uterine adaptation to the growing myoma. Hence, the pseudocapsule induces displacement on the myometrium, which is not destructive since the integrity and contractility of uterine structure is maintained. Extensive research conducted on the myoma and its pseudocapsule has produced important data. Scientific research is still trying to clarify some of the evidence regarding the influence of myomas on infertility, especially in the case of intramural myomas. During fertility-sparing myoma surgery, data suggest that during myoma removal the pseudocapsule should be preserved. However, unsolved issues still exist on the cesarean myomectomy technique, since the age of pregnancy has been increasing in the new millennium, so patients present with myomas which should be removed before and during the cesarean section, or prior to applying for medically-assisted reproduction. PMID:26785282

  5. Plasma afterburners and related issues

    NASA Astrophysics Data System (ADS)

    Huang, Chengkun

    2006-10-01

    In plasma wakefield acceleration experiments, the drive beam moves at the speed of light in the plasma and excites an accelerating plasma wakefield behind the driver. Therefore it is possible to use a trailing electron beam to extract energy from the plasma wave wake. Such a design, called the plasma afterburner, has been proposed to double the energy of the incoming beam train for a future linear collider. We investigate the nonlinear beam-plasma interaction in such scenario using a 3D computer modeling code, QuickPIC. We will report on the simulation results of a 1 TeV plasma afterburner design. Several issues such as efficient beam-loading and the stability of the beam in the plasma are also analyzed. The electron hosing instability in the blow-out regime of plasma wakefield acceleration is also investigated using linear perturbation theory upon the electron blow-out trajectory. The growth of the hosing instability is found to be affected by the plasma self-fields, the relativistic mass, the axial motion of plasma electrons and the position-dependent ion channel radius respectively. Therefore the hosing growth has dependence on the beam current, which is not found in the fluid theory. PIC simulations agree very well with this new theory.

  6. Teachers' Beliefs about Pedagogy and Related Issues

    ERIC Educational Resources Information Center

    Snider, Vicki E.; Roehl, Rebecca

    2007-01-01

    This study explores teachers' beliefs about pedagogical issues as well as related educational and professional issues. Six hundred K-12 teachers in three Midwestern states received surveys and 60% returned them. Results of the survey indicated that teachers were relatively unified in their beliefs, and few differences emerged around demographic…

  7. Priming Addition Facts with Semantic Relations

    ERIC Educational Resources Information Center

    Bassok, Miriam; Pedigo, Samuel F.; Oskarsson, An T.

    2008-01-01

    Results from 2 relational-priming experiments suggest the existence of an automatic analogical coordination between semantic and arithmetic relations. Word pairs denoting object sets served as primes in a task that elicits "obligatory" activation of addition facts (5 + 3 activates 8; J. LeFevre, J. Bisanz, & L. Mrkonjic, 1988). Semantic relations…

  8. Priming addition facts with semantic relations.

    PubMed

    Bassok, Miriam; Pedigo, Samuel F; Oskarsson, An T

    2008-03-01

    Results from 2 relational-priming experiments suggest the existence of an automatic analogical coordination between semantic and arithmetic relations. Word pairs denoting object sets served as primes in a task that elicits "obligatory" activation of addition facts (5 + 3 activates 8; J. LeFevre, J. Bisanz, & L. Mrkonjic, 1988). Semantic relations between the priming words were either aligned or misaligned with the structure of addition (M. Bassok, V. M. Chase, & S. A. Martin, 1998). Obligatory activation of addition facts occurred when the digits were primed by categorically related words (tulips-daisies), which are aligned with addition, but did not occur when the digits were primed by unrelated words (hens-radios, Experiment 1) or by functionally related words (records-songs, Experiment 2), which are misaligned with addition. These findings lend support to the viability of automatic analogical priming (B. A. Spellman, K. J. Holyoak, & R. G. Morrison, 2001) and highlight the relevance of arithmetic applications to theoretical accounts of mental arithmetic. PMID:18315410

  9. Sustainability issues in laser-based additive manufacturing

    NASA Astrophysics Data System (ADS)

    Sreenivasan, R.; Goel, A.; Bourell, D. L.

    Sustainability is a consideration of resource utilization without depletion or adverse environmental impact. In manufacturing, important sustainability issues include energy consumption, waste generation, water usage and the environmental impact of the manufactured part in service. This paper deals with three aspects of sustainability as it applies to additive manufacturing. First is a review of the research needs for energy and sustainability as applied to additive manufacturing based on the 2009 Roadmap for Additive Manufacturing Workshop. The second part is an energy assessment for selective laser sintering (SLS) of polymers. Using polyamide powder in a 3D Systems Vanguard HiQ Sinterstation, energy loss during a build was measured due to the chamber heaters, the roller mechanism, the piston elevators and the laser. This accounted for 95% of the total energy consumption. An overall energy assessment was accomplished using eco-indicators. The last topic is electrochemical deposition of porous SLS non-polymeric preforms. The goal is to reduce energy consumption in SLS of non-polymeric materials. The approach was to mix a transient binder with the material, to create an SLS green part, to convert the binder, and then to remove the open, connected porosity and to densify the part by chemical deposition at room temperature within the pore network. The model system was silicon carbide powder mixed with a phenolic transient binder coupled with electrolytic deposition of nickel. Deposition was facilitated by inserting a conductive graphite cathode in the part center to draw the positive nickel ions through the interconnected porous network and to deposit them on the pore walls. The Roadmap for Additive Manufacturing Workshop was sponsored by the National Science Foundation under Grant CMMI-0906212 and by the Office of Naval Research under Grant N00014-09-1-0558. The electrolytic deposition research was sponsored by the National Science Foundation, Grant CMMI-0926316.

  10. 78 FR 6273 - Rules Relating to Additional Medicare Tax

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Internal Revenue Service 26 CFR Parts 1 and 31 RIN 1545-BK54 Rules Relating to Additional Medicare Tax Correction In proposed rule document 2012-29237, appearing on pages 72268- 72277 in the issue of...

  11. Similarity issues of confluence of fuzzy relations

    NASA Astrophysics Data System (ADS)

    Kuhr, Tomas; Vychodil, Vilem

    2012-04-01

    We study similarity issues of confluence and related properties of fuzzy relations. The ordinary notions of divergence, convergence, convertibility, and confluence are essential properties of relations which appear in abstract rewriting systems. In a graded setting, we can introduce analogous notions related to the idea of approximate rewriting. This paper is a continuation of our previous paper (Belohlavek et al. 2010), where we have introduced such notions using residuated structures of truth degrees, leaving the ordinary notions a particular case when the underlying structure of truth degrees is the two-valued Boolean algebra. In this paper, we focus on similarity issues of confluence and present formulas which provide approximations of degrees of confluence and related properties based on similarity of the original fuzzy relations.

  12. [National Issues Relating to Children and Families].

    ERIC Educational Resources Information Center

    Cranston, Alan

    This speech by the chairman of the Child and Human Development Subcommittee of the Senate Labor and Human Resources Committee focuses on issues relating to the needs and problems of children and families. Programs under the jurisdiction of the Subcommittee include child abuse, child care, domestic violence, aspects of adoption and foster care…

  13. Addressing Issues Related to Technology and Engineering

    ERIC Educational Resources Information Center

    Technology Teacher, 2008

    2008-01-01

    This article presents an interview with Michael Hacker and David Burghardt, codirectors of Hoftra University's Center for Technological Literacy. Hacker and Burghardt address issues related to technology and engineering. They argue that teachers need to be aware of the problems kids are facing, and how to present these problems in an engaging…

  14. Teachers' Attitudes Toward Death-Related Issues

    ERIC Educational Resources Information Center

    Perkes, A. Cordell

    1978-01-01

    Reports a study to assess teachers attitudes toward death-related issues. A questionnaire was given to 61 teachers in a graduate education course. It was found that the teachers tended to favor liberal abortion laws (67 percent), euthanasia (83 percent), and the majority (65 percent) believed in life after death. (SLH)

  15. Thrombophilia related issues in women and children.

    PubMed

    Hoffman, Ron; Brenner, Benjamin

    2005-02-01

    Women experience increased thrombotic risk at pregnancy and puerperium as well as during hormonal therapy with oral contraceptives or hormone replacement therapy. Physiological and anatomical changes in pregnancy contribute to the hypercoagulable situation. Women with thrombophilia have an increased risk for venous and arterial thromboembolism as well as for gestational vascular complications including fetal loss, pre-eclampsia, placental abruption, and fetal growth restriction. Children are at increased thrombotic risk, particularly at the neonatal period, and may express thrombosis often in association with thrombophilia. This article will focuses on the clinical association, pathogenesis, and treatment of thrombophilia-related issues in women and children. PMID:15706481

  16. Credibility Issues Related to Testing Programs.

    ERIC Educational Resources Information Center

    Fleming, Margaret

    The implementation of a district-wide testing program requires careful consideration of credibility issues. These issues have been frequently overlooked or treated casually by test developers and users alike. It is well enough to study the reliability and validity issues involved when selecting instrumentation. It is also necessary to identify…

  17. 21 CFR 170.18 - Tolerances for related food additives.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 3 2014-04-01 2014-04-01 false Tolerances for related food additives. 170.18... (CONTINUED) FOOD ADDITIVES General Provisions § 170.18 Tolerances for related food additives. (a) Food... food additives. (b) Tolerances established for such related food additives may limit the amount of...

  18. 21 CFR 570.18 - Tolerances for related food additives.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Tolerances for related food additives. 570.18... (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES General Provisions § 570.18 Tolerances for related food additives. (a) Food additives that cause similar or related pharmacological...

  19. 21 CFR 570.18 - Tolerances for related food additives.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Tolerances for related food additives. 570.18... (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES General Provisions § 570.18 Tolerances for related food additives. (a) Food additives that cause similar or related pharmacological...

  20. 21 CFR 570.18 - Tolerances for related food additives.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 6 2014-04-01 2014-04-01 false Tolerances for related food additives. 570.18... (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES General Provisions § 570.18 Tolerances for related food additives. (a) Food additives that cause similar or related pharmacological...

  1. 21 CFR 570.18 - Tolerances for related food additives.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 6 2012-04-01 2012-04-01 false Tolerances for related food additives. 570.18... (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES General Provisions § 570.18 Tolerances for related food additives. (a) Food additives that cause similar or related pharmacological...

  2. 21 CFR 170.18 - Tolerances for related food additives.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 3 2012-04-01 2012-04-01 false Tolerances for related food additives. 170.18... (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES General Provisions § 170.18 Tolerances for related food additives. (a) Food additives that cause similar or related pharmacological effects will...

  3. 21 CFR 170.18 - Tolerances for related food additives.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 3 2011-04-01 2011-04-01 false Tolerances for related food additives. 170.18... (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES General Provisions § 170.18 Tolerances for related food additives. (a) Food additives that cause similar or related pharmacological effects will...

  4. 21 CFR 170.18 - Tolerances for related food additives.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 3 2013-04-01 2013-04-01 false Tolerances for related food additives. 170.18... (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES General Provisions § 170.18 Tolerances for related food additives. (a) Food additives that cause similar or related pharmacological effects will...

  5. 21 CFR 170.18 - Tolerances for related food additives.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Tolerances for related food additives. 170.18... (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES General Provisions § 170.18 Tolerances for related food additives. (a) Food additives that cause similar or related pharmacological effects will...

  6. Nuclear power plant safety related pump issues

    SciTech Connect

    Colaccino, J.

    1996-12-01

    This paper summarizes of a number of pump issues raised since the Third NRC/ASME Symposium on Valve and Pump Testing in 1994. General issues discussed include revision of NRC Inspection Procedure 73756, issuance of NRC Information Notice 95-08 on ultrasonic flow meter uncertainties, relief requests for tests that are determined by the licensee to be impractical, and items in the ASME OM-1995 Code, Subsection ISTB, for pumps. The paper also discusses current pump vibration issues encountered in relief requests and plant inspections - which include smooth running pumps, absolute vibration limits, and vertical centrifugal pump vibration measurement requirements. Two pump scope issues involving boiling water reactor waterlog and reactor core isolation cooling pumps are also discussed. Where appropriate, NRC guidance is discussed.

  7. Environmental Awareness: Relating Current Issues to Biology.

    ERIC Educational Resources Information Center

    DeFina, Anthony

    1995-01-01

    Presents examples of incorporating environmental issues into lesson plans to raise the level of students' environmental awareness. Topics include: ecology, taxonomy, biochemistry, energy reactions, cell structure and function, genetics and development, and human biology. (JRH)

  8. Children with Cancer: School Related Issues

    ERIC Educational Resources Information Center

    Gartin, Barbara C.; Murdick, Nikki L.

    2009-01-01

    School gives purpose to a student's life. Today, students with cancer and cancer survivors are encouraged to continue their educational experiences to maintain a sense of normalcy. This manuscript discusses the research findings on medical, physical, and cognitive issues that students with cancer and cancer survivors may encounter in their…

  9. Health Related Legal Issues in Education.

    ERIC Educational Resources Information Center

    Thomas, Stephen B.

    This monograph analyzes health and safety issues in education in terms of relevant constitutional and statutory provisions. Chapter 1, an introduction, summarizes Fourteenth Amendment equal protection and due process clauses and defines "handicapped" under the Rehabilitation Act. State assistance and student eligibility under the Education for All…

  10. Radiation safety issues related to radiolabeled antibodies. [Contains glossary

    SciTech Connect

    Barber, D.E.; Baum, J.W.; Meinhold, C. B. )

    1991-03-01

    Techniques related to the use of radiolabeled antibodies in humans are reviewed and evaluated in this report. It is intended as an informational resource for the US Nuclear Regulatory Commission (NRC) and NRC licensees. Descriptions of techniques and health and safety issues are provided. Principal methods for labeling antibodies are summarized to help identify related radiation safety problems in the preparation of dosages for administration to patients. The descriptions are derived from an extensive literature review and consultations with experts in the field. A glossary of terms and acronyms is also included. An assessment was made of the extent of the involvement of organizations (other than the NRC) with safety issues related to radiolabeled antibodies, in order to identify regulatory issues which require attention. Federal regulations and guides were also reviewed for their relevance. A few (but significant) differences between the use of common radiopharmaceuticals and radiolabeled antibodies were observed. The clearance rate of whole, radiolabeled immunoglobulin is somewhat slower than common radiopharmaceuticals, and new methods of administration are being used. New nuclides are being used or considered (e.g., Re-186 and At-211) for labeling antibodies. Some of these nuclides present new dosimetry, instrument calibration, and patient management problems. Subjects related to radiation safety that require additional research are identified. 149 refs., 3 figs., 20 tabs.

  11. Environmental issues related to biomass: An overview

    SciTech Connect

    Hughes, M.; Ranney, J.W.

    1993-12-31

    Now that public attention has grown increasingly focused on environmentalism and climate change, the commercial use of biomass could greatly accelerate. Renewable feedstocks like biomass can provide better environmentally balanced sources of energy and other nonfood products than fossil fuels. The future of biomass is uncertain, however, because public attention focuses on both its potential and its challenges. This paper is divided into five sections. Section 2 briefly addresses economic environmental issues. The extent to which externalities are accounted for in the market price of fuels plays a significant role in determining both the ultimate size of biofuel markets and the extent of the environmental benefits of feedstock cultivation and conversion processes. Sections 3 and 4 catalog the main hazards and benefits that are likely to arise in the large-scale commercialization of biomass fuel and note where the major uncertainties lay. Environmental issues arise with the cultivation of each feedstock and with each step in the process of its conversion to fuel. Feedstocks are discussed in Section 3 in terms of three main groups: wastes, energy crops, and traditional agricultural crops. In Section 4, conversion processes are also divided into three groups, on the basis of the end energy carrier: gas, liquid, and solid and electricity. Section 5 provides a conclusion and summary.

  12. Issues in the Ethics of Public Relations.

    ERIC Educational Resources Information Center

    Hamilton, Peter K.

    There is little doubt that the field of public relations needs to be concerned with both the ethical standards and behaviors of practitioners and the perceptions of these standards and actions held by clients, other communications professionals, and the public. What constitutes ethical standards and practices, however, continues to be debated…

  13. Legal Issues Related to Extracurricular Activities.

    ERIC Educational Resources Information Center

    Cary, Jean M.

    1992-01-01

    Legal questions related to extracurricular activities include the following: (1) students "right" to participate; (2) kinds of fees or insurance requirements; (3) regulation of contracts and finances; (4) membership policies acceptable in light of Title IX's prohibition on sex discrimination; (5) reduction of risk of tort liability; and (6) how…

  14. Anticancer oral therapy: emerging related issues.

    PubMed

    Banna, Giuseppe Luigi; Collovà, Elena; Gebbia, Vittorio; Lipari, Helga; Giuffrida, Pietro; Cavallaro, Sebastiano; Condorelli, Rosaria; Buscarino, Calogero; Tralongo, Paolo; Ferraù, Francesco

    2010-12-01

    The use of oral anticancer drugs has shown a steady increase. Most patients prefer anticancer oral therapy to intravenous treatment primarily for the convenience of a home-based therapy, although they require that the efficacy of oral therapy must be equivalent and toxicity not superior than those expected with the intravenous treatment. A better patient compliance, drug tolerability, convenience and possible better efficacy for oral therapy as compared to intravenous emerge as the major reasons to use oral anticancer agents among oncologists. Inter- and intra-individual pharmacokinetic variations in the bioavailability of oral anticancer drugs may be more relevant than for intravenous agents. Compliance is particularly important for oral therapy because it determines the dose-intensity of the treatment and ultimately treatment efficacy and toxicity. Patient stands as the most important determinant of compliance. Possible measures for an active and safe administration of oral therapy include a careful preliminary medical evaluation and selection of patients based on possible barriers to an adequate compliance, pharmacologic issues, patient-focused education, an improvement of the accessibility to healthcare service, as well as the development of home-care nursing symptom-focused interventions. Current evidences show similar quality of life profile between oral and intravenous treatments, although anticancer oral therapy seems to be more convenient in terms of administration and reduced time lost for work or other activities. Regarding cost-effectiveness, current evidences are in favor of oral therapy, mainly due to reduced need of visits and/or day in hospital for the administration of the drug and/or the management of adverse events. PMID:20570443

  15. Issues Management and the Use of Technologies in Public Relations.

    ERIC Educational Resources Information Center

    Ramsey, Shirley A.

    1993-01-01

    Finds that members of the Issues Management Association were more positively involved with two procedures--"environmental scanning for emerging issues" and "developing communication plans about the issues"--than were other public relations practitioners. Finds that respondents were highly likely to use advanced communication technologies to help…

  16. Guidelines for Teaching Science-Related Social Issues.

    ERIC Educational Resources Information Center

    Social Education, 1983

    1983-01-01

    Science is a social issue. The examination of scientific issues offers an excellent opportunity for helping students develop a synthesized perspective on science related issues--a synthesis of the technical data coupled with social, political, economic, ethical, and philosophical information. (RM)

  17. 21 CFR 570.18 - Tolerances for related food additives.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Tolerances for related food additives. 570.18 Section 570.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES General Provisions § 570.18...

  18. 78 FR 6272 - Rules Relating to Additional Medicare Tax; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-30

    ..., December 5, 2012 (77 FR 72268). The proposed regulations are relating to Additional Hospital Insurance Tax... proposed rulemaking and notice of public hearing (REG-130074-11), that was the subject of FR Doc. 2012... Internal Revenue Service 26 CFR Part 1 RIN 1545-BK54 Rules Relating to Additional Medicare Tax;...

  19. Current and Emerging Labor Relations Issues in Higher Education

    ERIC Educational Resources Information Center

    Kahn, Kenneth

    1974-01-01

    Reviews current case law alerting public institutions as well as those covered under the National Labor Relations Act to consequences and problems of faculty unionization, including issues of conflict between the faculty senate and a union, exclusive representation, supervisory status of faculty members, and scope of negotiation issues. (JT)

  20. Economic and Monetary Union: Issues Relating to Education for Citizenship.

    ERIC Educational Resources Information Center

    Davies, Ian

    1998-01-01

    Summarizes some key issues in debates about the introduction of economic and monetary union within the European Union, including some educational considerations. Describes a method used to teach undergraduates in the United Kingdom about the European Union. Discusses these issues in relation to citizenship education. (SLD)

  1. 40 CFR 300.220 - Related Title III issues.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... are found in 40 CFR part 355. ... 40 Protection of Environment 27 2010-07-01 2010-07-01 false Related Title III issues. 300.220 Section 300.220 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND,...

  2. 40 CFR 300.220 - Related Title III issues.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... are found in 40 CFR part 355. ... 40 Protection of Environment 28 2014-07-01 2014-07-01 false Related Title III issues. 300.220 Section 300.220 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND,...

  3. 40 CFR 300.220 - Related Title III issues.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... are found in 40 CFR part 355. ... 40 Protection of Environment 29 2013-07-01 2013-07-01 false Related Title III issues. 300.220 Section 300.220 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND,...

  4. 40 CFR 300.220 - Related Title III issues.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... are found in 40 CFR part 355. ... 40 Protection of Environment 29 2012-07-01 2012-07-01 false Related Title III issues. 300.220 Section 300.220 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND,...

  5. 40 CFR 300.220 - Related Title III issues.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... are found in 40 CFR part 355. ... 40 Protection of Environment 28 2011-07-01 2011-07-01 false Related Title III issues. 300.220 Section 300.220 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND,...

  6. Could Talk Therapy Ease Chemo-Related Memory Issues?

    MedlinePlus

    ... 158606.html Could Talk Therapy Ease Chemo-Related Memory Issues? Researchers suggest their approach could improve survivors' ... developed a cognitive-behavioral therapy (CBT) program called Memory and Attention Adaptation Training to help cancer survivors ...

  7. How do medical journalists treat cancer-related issues?

    PubMed Central

    Nakada, Haruka; Tsubokura, Masaharu; Kishi, Yukiko; Yuji, Koichiro; Matsumura, Tomoko; Kami, Masahiro

    2015-01-01

    Cancer patients can obtain information about their illness through a variety of media sources. Therefore, it is important to know how medical journalists treat cancer-related issues; to that end, we sent self-administered questionnaires to 364 journalists in 82 organisations who had reported on medical issues for the Japanese media, asking for their reasons for reporting on cancer-related issues and the difficulties they had faced. The most common reason for reporting on health-related issues was their personal interest in a particular issue (n = 36). They mainly covered conventional therapies (n = 33), healthcare policy (n = 30), new therapies (n = 25), and diagnosis (n = 25). All of the journalists that were surveyed experienced some difficulties in reporting health issues. Significant concerns included the quality of information (n = 36), social impact (n = 35), lack of technical knowledge (n = 35), and difficulty in understanding technical terms (n = 35). Journalists commonly used personal networks, including physicians, as information sources (n = 42), as well as social media (e.g., e-mail, Twitter and Facebook) (n = 32). Topic selection was biased, with 35 of 48 journalists having never reported on topics concerning hospices. Physicians were the most trusted source of information about cancer, and journalists attached high importance to interviewing them. As medical knowledge is advancing rapidly, journalists may have increasing difficulty covering cancer-related issues. PMID:25729415

  8. Thermally-related safety issues associated with thermal batteries.

    SciTech Connect

    Guidotti, Ronald Armand

    2006-06-01

    Thermal batteries can experience thermal runaway under certain usage conditions. This can lead to safety issues for personnel and cause damage to associated test equipment if the battery thermally self destructs. This report discusses a number of thermal and design related issues that can lead to catastrophic destruction of thermal batteries under certain conditions. Contributing factors are identified and mitigating actions are presented to minimize or prevent undesirable thermal runaway.

  9. Monitoring asthma in childhood: management-related issues.

    PubMed

    Rottier, Bart L; Eber, Ernst; Hedlin, Gunilla; Turner, Steve; Wooler, Edwina; Mantzourani, Eva; Kulkarni, Neeta

    2015-06-01

    Management-related issues are an important aspect of monitoring asthma in children in clinical practice. This review summarises the literature on practical aspects of monitoring including adherence to treatment, inhalation technique, ongoing exposure to allergens and irritants, comorbid conditions and side-effects of treatment, as agreed by the European Respiratory Society Task Force on Monitoring Asthma in Childhood. The evidence indicates that it is important to discuss adherence to treatment in a non-confrontational way at every clinic visit, and take into account a patient's illness and medication beliefs. All task force members teach inhalation techniques at least twice when introducing a new inhalation device and then at least annually. Exposure to second-hand tobacco smoke, combustion-derived air pollutants, house dust mites, fungal spores, pollens and pet dander deserve regular attention during follow-up according to most task force members. In addition, allergic rhinitis should be considered as a cause for poor asthma control. Task force members do not screen for gastro-oesophageal reflux and food allergy. Height and weight are generally measured at least annually to identify individuals who are susceptible to adrenal suppression and to calculate body mass index, even though causality between obesity and asthma has not been established. In cases of poor asthma control, before stepping up treatment the above aspects of monitoring deserve closer attention. PMID:26028632

  10. University Students' Perceptions of Issues Related to Agriculture.

    ERIC Educational Resources Information Center

    Terry, Robert, Jr.; Lawver, David E.

    1995-01-01

    Telephone interviews with 390 of 400 college students revealed an overall favorable impression of food safety and agriculture's impact on the economy and environment. Males were more positive about animal welfare and production agriculture. Gender, college major, and hometown were related to attitudes about agriculture issues. (SK)

  11. SMOG CHAMBER EXPERIMENTS TO TEST OXIDANT RELATED CONTROL STRATEGY ISSUES

    EPA Science Inventory

    Outdoor smog chamber experiments were performed to address various issues relating to ozone (O3) production and oxidant control strategies. Temperature effects on single hydrocarbon-NOx systems were studied. Propylene-NOx systems were modeled with particular attention to peroxyni...

  12. 76 FR 63573 - Roundtable on Issues Relating to Conflict Minerals

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... COMMISSION 17 CFR Parts 229 and 249 Roundtable on Issues Relating to Conflict Minerals AGENCY: Securities and... conflict minerals originating in the Democratic Republic of the Congo and adjoining countries. Roundtable... reporting regulations regarding the use of conflict minerals from the Democratic Republic of the Congo...

  13. Issues Related to Equipment and the Dietary Guidelines for Americans.

    ERIC Educational Resources Information Center

    Nettles, Mary Frances

    A multi-year project was initiated to examine production equipment issues related to implementation of the Dietary Guidelines for Americans (DGA). The purposes of the research project were to determine foodservice directors' opinions regarding use and appropriateness of equipment in school foodservice, to identify the number and variety of menu…

  14. Everyday Issues Related to Justice and Other Gospel Values.

    ERIC Educational Resources Information Center

    Kealey, Robert J.

    This manual presents situations that occur in the lives of most children and suggests to the teacher related activities which might cause students to reflect on the deeper meaning and significance of the situations. It seeks to make the teacher, and thus students, aware of the fact that peace, justice, and other value issues are part of daily…

  15. Older Adults: Work-Related Issues and Implications for Counseling.

    ERIC Educational Resources Information Center

    Brewington, Janice O.; Nassar-McMillan, Sylvia

    2000-01-01

    In a period of business downsizing, older workers are at risk for unemployment. Finding a suitable replacement job is difficult and can lead to emotional and financial distress. Counselors need to be aware of the work-related issues facing older adults and understand the suitable interventions that will help them make smoother career and life…

  16. Direct normal irradiance related definitions and applications: The circumsolar issue

    SciTech Connect

    Blanc, P.; Espinar, B.; Geuder, N.; Gueymard, C.; Meyer, R.; Pitz-Paal, R.; Reinhardt, B.; Renne, D.; Segupta, M.; Wald, L.; Wilbert, S.

    2014-10-21

    The direct irradiance received on a plane normal to the sun, called direct normal irradiance (DNI), is of particular relevance to concentrated solar technologies, including concentrating solar thermal plants and concentrated photovoltaic systems. Following various standards from the International Organization for Standardization (ISO), the DNI definition is related to the irradiance from a small solid angle of the sky, centered on the position of the sun. Half-angle apertures of pyrheliometers measuring DNI have varied over time, up to ≈10°. The current recommendation of the World Meteorological Organization (WMO) for this half-angle is 2.5°. Solar concentrating collectors have an angular acceptance function that can be significantly narrower, especially for technologies with high concentration ratios. The disagreement between the various interpretations of DNI, from the theoretical definition used in atmospheric physics and radiative transfer modeling to practical definitions corresponding to specific measurements or conversion technologies is significant, especially in the presence of cirrus clouds or large concentration of aerosols. Under such sky conditions, the circumsolar radiation—i.e. the diffuse radiation coming from the vicinity of the sun—contributes significantly to the DNI ground measurement, although some concentrating collectors cannot utilize the bulk of it. These issues have been identified in the EU-funded projects MACC-II (Monitoring Atmospheric Composition and Climate-Interim Implementation) and SFERA (Solar Facilities for the European Research Area), and have been discussed within a panel of international experts in the framework of the Solar Heating and Cooling (SHC) program of the International Energy Agency’s (IEA’s) Task 46 “Solar Resource Assessment and Forecasting”. In accordance with these discussions, the terms of reference related to DNI are specified here. The important role of circumsolar radiation is evidenced

  17. Direct normal irradiance related definitions and applications: The circumsolar issue

    DOE PAGESBeta

    Blanc, P.; Espinar, B.; Geuder, N.; Gueymard, C.; Meyer, R.; Pitz-Paal, R.; Reinhardt, B.; Renne, D.; Segupta, M.; Wald, L.; et al

    2014-10-21

    The direct irradiance received on a plane normal to the sun, called direct normal irradiance (DNI), is of particular relevance to concentrated solar technologies, including concentrating solar thermal plants and concentrated photovoltaic systems. Following various standards from the International Organization for Standardization (ISO), the DNI definition is related to the irradiance from a small solid angle of the sky, centered on the position of the sun. Half-angle apertures of pyrheliometers measuring DNI have varied over time, up to ≈10°. The current recommendation of the World Meteorological Organization (WMO) for this half-angle is 2.5°. Solar concentrating collectors have an angular acceptancemore » function that can be significantly narrower, especially for technologies with high concentration ratios. The disagreement between the various interpretations of DNI, from the theoretical definition used in atmospheric physics and radiative transfer modeling to practical definitions corresponding to specific measurements or conversion technologies is significant, especially in the presence of cirrus clouds or large concentration of aerosols. Under such sky conditions, the circumsolar radiation—i.e. the diffuse radiation coming from the vicinity of the sun—contributes significantly to the DNI ground measurement, although some concentrating collectors cannot utilize the bulk of it. These issues have been identified in the EU-funded projects MACC-II (Monitoring Atmospheric Composition and Climate-Interim Implementation) and SFERA (Solar Facilities for the European Research Area), and have been discussed within a panel of international experts in the framework of the Solar Heating and Cooling (SHC) program of the International Energy Agency’s (IEA’s) Task 46 “Solar Resource Assessment and Forecasting”. In accordance with these discussions, the terms of reference related to DNI are specified here. The important role of circumsolar radiation is

  18. Assistance to States on Policies Related to Wind Energy Issues

    SciTech Connect

    Brown, Matthew, H; Decesaro, Jennifer; DOE Project Officer - Keith Bennett

    2005-07-15

    This final report summarizes work carried out under agreement with the US Department of Energy, related to wind energy policy issues. This project has involved a combination of outreach and publications on wind energy, with a specific focus on educating state-level policymakers. Education of state policymakers is vitally important because state policy (in the form of incentives or regulation) is a crucial part of the success of wind energy. State policymakers wield a significant influence over all of these policies. They are also in need of high quality, non-biased educational resources which this project provided. This project provided outreach to legislatures, in the form of meetings designed specifically for state legislators and legislative staff, responses to information requests on wind energy, and publications. The publications addressed: renewable energy portfolio standards, wind energy transmission, wind energy siting, case studies of wind energy policy, avian issues, economic development, and other related issues. These publications were distributed to legislative energy committee members, and chairs, legislative staff, legislative libraries, and other related state officials. The effect of this effort has been to provide an extensive resource of information about wind information for state policymakers in a form that is useful to them. This non-partisan information has been used as state policymakers attempt to develop their own policy proposals related to wind energy in the states.

  19. Artificial intelligence issues related to automated computing operations

    NASA Technical Reports Server (NTRS)

    Hornfeck, William A.

    1989-01-01

    Large data processing installations represent target systems for effective applications of artificial intelligence (AI) constructs. The system organization of a large data processing facility at the NASA Marshall Space Flight Center is presented. The methodology and the issues which are related to AI application to automated operations within a large-scale computing facility are described. Problems to be addressed and initial goals are outlined.

  20. Additives

    NASA Technical Reports Server (NTRS)

    Smalheer, C. V.

    1973-01-01

    The chemistry of lubricant additives is discussed to show what the additives are chemically and what functions they perform in the lubrication of various kinds of equipment. Current theories regarding the mode of action of lubricant additives are presented. The additive groups discussed include the following: (1) detergents and dispersants, (2) corrosion inhibitors, (3) antioxidants, (4) viscosity index improvers, (5) pour point depressants, and (6) antifouling agents.

  1. [An exploration of the issues involved in family related research].

    PubMed

    Huang, Hsiu-Li; Dai, Yu-Tzu; Yeh, Mei Chang; Weng, Li-Chueh

    2007-06-01

    Nowadays, health care delivery systems are changing from hospital-based services to more family-oriented or community-oriented care. The development of family nursing and family research is the focus of more attention than ever before. A family is composed of individuals. It combines the characteristics of individuals and collective groups, which makes family research more complex than studies of individuals. Consequently, research into family-oriented areas presents additional challenges concerning conceptual methodological issues. This article focuses on the issues of family research concepts, research designs, definitions of family, sampling, study tools, and data analysis. In order to promote high-quality family research outcomes, we propose below suggestions to serve as a guide to conducting family research: (1) identify the definition of family involved in a particular research question and choose a suitable methodology; (2) determine the number of family members and un its of analysis on theoretical bases; (3) select high-validity, high-reliability research tools in answering research questions; (4) analysis methods must match the concept of family and the characteristics of the units of analysis; (5) ethical issues must be respected in the recruitment of family members. PMID:17554671

  2. Materials Issues Related to Catalysts for Treatment of Diesel Exhaust

    SciTech Connect

    Narula, Chaitanya Kumar; Daw, C Stuart; Hoard, John W.; Hammer, T.

    2005-01-01

    The driver for lean NO{sub x} treatment is the need to meet regulatory standards for diesel engines and gasoline direct injection spark-ignited engines that offer better fuel economy. Efforts over the last decade have been focused toward finding an active lean NO{sub x} catalyst that can reduce NO{sub x} under oxidizing conditions or strategies such as selective catalytic reduction (SCR), plasma-catalysis, plasma catalyst SCR, and lean NO{sub x} traps with varying degrees of success. At present, it appears that SCR with urea and lean NO{sub x} traps are the leading contender technologies for commercial deployment. Key issues that remain to be resolved for these two technologies include byproduct formation, dosing control, and durability. In this review, we summarize material-related issues that are unique to each of these technologies, and point out the improvements necessary to facilitate their deployment.

  3. Issues related to line-oriented flight training

    NASA Technical Reports Server (NTRS)

    Lauber, J. K.

    1981-01-01

    The use of a training simulator along with carefully structured, detailed, line trip scenarios was envisioned by NASA as a means of providing a controllable, repeatable way to observe line crews in a highly realistic simulation of their working environment and obtain better understanding operationally significant human factors problems and issues. Relevant research done by the agency and the results of full-mission simulation scenarios revealed potential implications for flight training. Aspects to be considered in creating training programs closely related to the actual line environment with a total crew application in real world incident experiences include: (1) operational, environmental, equipment, and crew problems in scenario design; (2) real time line oriented flight training operation; (3) performance assessment and debriefing; (4) instructor qualification and training; and (5) other issues such as ub un initial, transition, and upgrade training; procedures developent and evaluation, and equipment evaluation.

  4. Telerobotic control issues related to real task applications in the space environment

    NASA Technical Reports Server (NTRS)

    Zimmerman, Wayne

    1990-01-01

    Recent findings concerning the definition of the expected control environment associated with the Space Station are examined. The range of expected near-term and far-term task applications for robotic systems is provided, and the essential control issues related to the application environment are derived. In addition, an approximate control envelope for teleoperated and autonomous robotic systems is established.

  5. Adherence issues related to sublingual immunotherapy as perceived by allergists

    PubMed Central

    Scurati, Silvia; Frati, Franco; Passalacqua, Gianni; Puccinelli, Paola; Hilaire, Cecile; Incorvaia, Cristoforo

    2010-01-01

    Objectives: Sublingual immunotherapy (SLIT) is a viable alternative to subcutaneous immunotherapy to treat allergic rhinitis and asthma, and is widely used in clinical practice in many European countries. The clinical efficacy of SLIT has been established in a number of clinical trials and meta-analyses. However, because SLIT is self-administered by patients without medical supervision, the degree of patient adherence with treatment is still a concern. The objective of this study was to evaluate the perception by allergists of issues related to SLIT adherence. Methods: We performed a questionnaire-based survey of 296 Italian allergists, based on the adherence issues known from previous studies. The perception of importance of each item was assessed by a VAS scale ranging from 0 to 10. Results: Patient perception of clinical efficacy was considered the most important factor (ranked 1 by 54% of allergists), followed by the possibility of reimbursement (ranked 1 by 34%), and by the absence of side effects (ranked 1 by 21%). Patient education, regular follow-up, and ease of use of SLIT were ranked first by less than 20% of allergists. Conclusion: These findings indicate that clinical efficacy, cost, and side effects are perceived as the major issues influencing patient adherence to SLIT, and that further improvement of adherence is likely to be achieved by improving the patient information provided by prescribers. PMID:20622914

  6. Codes of practice and related issues in biomedical waste management

    SciTech Connect

    Moy, D.; Watt, C.

    1996-12-31

    This paper outlines the development of a National Code of Practice for biomedical waste management in Australia. The 10 key areas addressed by the code are industry mission statement; uniform terms and definitions; community relations - public perceptions and right to know; generation, source separation, and handling; storage requirements; transportation; treatment and disposal; disposal of solid and liquid residues and air emissions; occupational health and safety; staff awareness and education. A comparison with other industry codes in Australia is made. A list of outstanding issues is also provided; these include the development of standard containers, treatment effectiveness, and reusable sharps containers.

  7. A Research on Issues Related to RFID Security and Privacy

    NASA Astrophysics Data System (ADS)

    Kim, Jongki; Yang, Chao; Jeon, Jinhwan

    Radio Frequency Identification (RFID) is a technology for automated identification of objects and people. RFID systems have been gaining more popularity in areas especially in supply chain management and automated identification systems. However, there are many existing and potential problems in the RFID systems which could threat the technology's future. To successfully adopt RFID technology in various applications, we need to develop the solutions to protect the RFID system's data information. This study investigates important issues related to privacy and security of RFID based on the recent literature and suggests solutions to cope with the problem.

  8. Software safety and reliability issues in safety-related systems

    SciTech Connect

    Zucconi, L.

    1992-09-01

    The increasing number of accidents attributed to computer-based systems is causing increased public awareness of the risk associated with these systems' use in safety-related applications. Examples include the Therac-25 medical LINAC deaths, the growing number of Airbus A320 crashes, the AT T Long-Lines disaster on Martin Luther King Day in 1990, the spate of regional telephone outages of the summer of 1991, and many more. How do safety and reliability sometimes conflict What practical computer system and software development technologies and processes can be applied to increase the safety and reliability of computer systems What are the technical and managerial issues contributing to the construction of less-than-safe computer-based systems How can systems engineers and software engineers work together. to address the issues related to safety and reliability of computer systems This paper will address these topics and include an assessment of the best current state-of-the-practice and upcoming technologies that will carry us into the 21st century.

  9. Safety and reliability issues in safety-related systems

    SciTech Connect

    Zucconi, L.

    1992-03-20

    The increasing number of accidents attributed to computer-based systems is causing increased public awareness of the risk associated with these systems` use in safety-related applications. Examples include the Therac-25 medical LINAC deaths, the growing number of Airbus A320 crashes, the AT&T Long-Lines disaster on Martin Luther King Day in 1990, the spate of regional telephone outages of the summer of 1991, and many more. How do safety and reliability sometimes conflict? What practical computer system and software development technologies and processes can be applied to increase the safety and reliability of computer systems? What are the technical and managerial issues contributing to the construction of less-than-safe computer-based systems? How can systems engineers and software engineers work together to address the issues related safety and reliability of computer systems? This paper will address these topics and include an assessment of the best current state-of-the-practice and of upcoming technologies that will carry us into the 21st century.

  10. Software safety and reliability issues in safety-related systems

    SciTech Connect

    Zucconi, L.

    1992-09-01

    The increasing number of accidents attributed to computer-based systems is causing increased public awareness of the risk associated with these systems` use in safety-related applications. Examples include the Therac-25 medical LINAC deaths, the growing number of Airbus A320 crashes, the AT&T Long-Lines disaster on Martin Luther King Day in 1990, the spate of regional telephone outages of the summer of 1991, and many more. How do safety and reliability sometimes conflict? What practical computer system and software development technologies and processes can be applied to increase the safety and reliability of computer systems? What are the technical and managerial issues contributing to the construction of less-than-safe computer-based systems? How can systems engineers and software engineers work together. to address the issues related to safety and reliability of computer systems? This paper will address these topics and include an assessment of the best current state-of-the-practice and upcoming technologies that will carry us into the 21st century.

  11. Safety and reliability issues in safety-related systems

    SciTech Connect

    Zucconi, L.

    1992-03-20

    The increasing number of accidents attributed to computer-based systems is causing increased public awareness of the risk associated with these systems' use in safety-related applications. Examples include the Therac-25 medical LINAC deaths, the growing number of Airbus A320 crashes, the AT T Long-Lines disaster on Martin Luther King Day in 1990, the spate of regional telephone outages of the summer of 1991, and many more. How do safety and reliability sometimes conflict What practical computer system and software development technologies and processes can be applied to increase the safety and reliability of computer systems What are the technical and managerial issues contributing to the construction of less-than-safe computer-based systems How can systems engineers and software engineers work together to address the issues related safety and reliability of computer systems This paper will address these topics and include an assessment of the best current state-of-the-practice and of upcoming technologies that will carry us into the 21st century.

  12. Relative Stabilities of Organic Compounds Using Benson's Additivity Rules.

    ERIC Educational Resources Information Center

    Vitale, Dale E.

    1986-01-01

    Shows how the structure-energy principle can be presented in organic chemistry (without having to resort to quantum mechanics) by use of Benson's Additive Rules. Examples of the application to several major classes of organic compounds are given.

  13. A Status Report on the SHADOZ (Southern Hemisphere Additional Ozonesondes) Project and Some Issues Affecting Ozone Climatology

    NASA Technical Reports Server (NTRS)

    Thompson, Anne M.; Witte, J. C.; McPeters, R. D.; Einaudi, Franco (Technical Monitor)

    2000-01-01

    SHADOZ aims to support the study of local and global patterns in stratospheric and tropospheric ozone and to provide a data set for the validation for satellite products and model calculations of ozone. Southern hemispheric tropical ozone is of particular interest because this region appears to have complex interplay among photochemical ozone formation (from biomass burning and lightning), stratospheric dynamics, convection and possibly cross-hemispheric transport. Balloon-borne ozone instrumentation (ozonesondes), joined with standard radiosondes for measurement of pressure, temperature and relative humidity, is used to collect profiles throughout the troposphere and lower- to mid-stratosphere. A network of 10 southern hemisphere tropical and subtropical stations, called the Southern Hemisphere ADditional OZonesondes (SHADOZ) project, has been established from operational sites to assemble sonde data for 1998-2000. A status report on the archive, with station operating characteristics, will be given, along with some operational issues that may affect data analysis and interpretation.

  14. Ethical issues related to epilepsy care in the developing world.

    PubMed

    Tan, Chong-Tin; Avanzini, Giuliano

    2009-05-01

    There are three major issues of ethical concern related to epilepsy care in the developing world. First, is it ethical for a developing country to channel its limited resources from direct epilepsy care to research? The main considerations in addressing this question are the particular research questions to be addressed and whether such research will bring direct benefits to the local community. Second, in a country with limited resources, when does ignoring the high treatment gap become an ethical issue? This question is of particular concern when the community has enough resources to afford treatment for its poor, yet is not providing such care because of gross wastage and misallocation of the national resources. Third, do countries with plentiful resources have an ethical responsibility to help relieve the high epilepsy treatment gap of poor countries? Indeed, we believe that reasonable health care is a basic human right, and that human rights transcend national boundaries. Although health care is usually the responsibility of the nation-state, many modern states in the developing world are arbitrary creations of colonization. There is often a long process from the establishment of a political-legal state to a mature functional nation. During the long process of nation building, help from neighboring countries is often required. PMID:19170738

  15. Tip-enhanced Raman spectroscopy: tip-related issues.

    PubMed

    Huang, Teng-Xiang; Huang, Sheng-Chao; Li, Mao-Hua; Zeng, Zhi-Cong; Wang, Xiang; Ren, Bin

    2015-11-01

    After over 15 years of development, tip-enhanced Raman spectroscopy (TERS) is now facing a very important stage in its history. TERS offers high detection sensitivity down to single molecules and a high spatial resolution down to sub-nanometers, which make it an unprecedented nanoscale analytical technique offering molecular fingerprint information. The tip is the core element in TERS, as it is the only source through which to support the enhancement effect and provide the high spatial resolution. However, TERS suffers and will continue to suffer from the limited availability of TERS tips with a high enhancement, good stability, and high reproducibility. This review focuses on the tip-related issues in TERS. We first discuss the parameters that influence the enhancement and spatial resolution of TERS and the possibility to optimize the performance of a TERS system via an in-depth understanding of the enhancement mechanism. We then analyze the methods that have been developed for producing TERS tips, including vacuum-based deposition, electrochemical etching, electrodeposition, electroless deposition, and microfabrication, with discussion on the advantages and weaknesses of some important methods. We also tackle the issue of lifetime and protection protocols of TERS tips which are very important for the stability of a tip. Last, some fundamental problems and challenges are proposed, which should be addressed before this promising nanoscale characterization tool can exert its full potential. Graphical Abstract ᅟ. PMID:26314483

  16. Mitigating Issues Related to the Modeling of Insurgent Recruitment

    NASA Astrophysics Data System (ADS)

    Briscoe, Erica; Trewhitt, Ethan; Weiss, Lora; Whitaker, Elizabeth

    Modeling the specific motivations and influences related to an individual's decision to become involved in insurgent warfare presents its own collection of unique challenges. The difficulty of the problem often necessitates simplifications that, while making the task more manageable, may inadvertently 'smooth away' critical aspects of the problem. Augmenting the challenge is that research into the motivations of terrorism has found there is not a definitive set of variables that serve as reliable indicators of an individual's involvement. This paper addresses techniques aimed toward mitigating issues that manifest in the modeling of insurgent recruitment so that these complications do not lessen the viability of models that are used in the prediction and evaluation of terrorist activity.

  17. Issues Related to the Updated 2014 Korean Guidelines for Tuberculosis

    PubMed Central

    2016-01-01

    Tuberculosis (TB) remains a major public health problem in South Korea. The Joint Committee for the Development of Korean Guidelines for Tuberculosis published the Korean Guidelines for Tuberculosis in 2011 to provide evidence-based practical recommendations to health care workers caring for patients with TB in South Korea. After reviewing recent national and international scientific data on TB, the committee updated the Korean guidelines for TB in 2014. This article presents some practical issues related to the 2014 updated guidelines: namely use of the Mycobacterium tuberculosis - polymerase chain reaction assay and the Xpert MTB/RIF assay in the diagnosis of TB, as well as medical treatment for patients with multidrug-resistant TB. PMID:26770228

  18. Statement Summarizing Research Findings on the Issue of the Relationship Between Food-Additive-Free Diets and Hyperkinesis in Children.

    ERIC Educational Resources Information Center

    Lipton, Morris; Wender, Esther

    The National Advisory Committee on Hyperkinesis and Food Additives paper summarized some research findings on the issue of the relationship between food-additive-free diets and hyperkinesis in children. Based on several challenge studies, it is concluded that the evidence generally refutes Dr. B. F. Feingold's claim that artificial colorings in…

  19. Immunotoxicity of the colour additive caramel colour III; a review on complicated issues in the safety evaluation of a food additive.

    PubMed

    Houben, G F; Penninks, A H

    1994-08-12

    Food additives can be regarded as the safest constituents of our daily food. Nevertheless, complicated issues with respect to their safety evaluation do also occur. In this review paper, some of these issues are illustrated by the description and evaluation of the research on the immunotoxicity of the food additive Caramel Colour III. Caramel Colour III is commonly used as a color additive in many products for human consumption. Toxicity studies conducted in the seventies demonstrated that administration of Caramel Colour III can cause a reduction in total white blood cell counts in rats, due to reduced lymphocyte counts. Studies reviewed in this paper demonstrated several other effects of Caramel Colour III on the immune system of rodents, including disturbed immune functions and changed resistance in infection models. In addition, studies in rats demonstrated that most of the effects occur only when the animals are fed a diet low in vitamin B6. The imidazole derivative 2-acetyl-4(5)-(1,2,3,4-tetrahydroxy-butyl)-imidazole (THI) was found to be responsible for the immunotoxicity. Issues such as the mechanism of action of THI and the role of vitamin B6 are discussed. Finally, the results of a human intervention study and the observed effect levels of THI in rats are discussed in terms of safety of the use of Caramel Colour III in our daily food supply. PMID:8079366

  20. Legislative and regulatory issues related to reusable launch systems

    NASA Astrophysics Data System (ADS)

    Peinemann, Manfred K. A.

    1996-03-01

    The development of reusable launch systems with private investment funds for primarily commercial launch services raises a number of novel legal and regulatory issues. The issues discussed include requirements for a whole new spectrum of safety and environmental issues; new certification rules, procedures and oversight organizations; liability and jurisdiction definitions, taxation treatments; government commitments and/or participation in commercial enterprises; and international legal and business issues. The satisfactory solution to all of these issues is a necessary condition for the development and operation of reusable launch vehicles to be a viable commercial enterprise.

  1. Addressing security issues related to virtual institute distributed activities

    NASA Astrophysics Data System (ADS)

    Stytz, Martin R.; Banks, Sheila B.

    2008-03-01

    One issue confounding the development and experimentation of distributed modeling and simulation environments is the inability of the project team to identify and collaborate with resources, both human and technical, from outside the United States. This limitation is especially significant within the human behavior representation area where areas such as cultural effects research and joint command team behavior modeling require the participation of various cultural and national representatives. To address this limitation, as well as other human behavior representation research issues, NATO Research and Technology Organization initiated a project to develop a NATO virtual institute that enables more effective and more collaborative research into human behavior representation. However, in building and operating a virtual institute one of the chief concerns must be the cyber security of the institute. Because the institute "exists" in cyberspace, all of its activities are susceptible to cyberattacks, subterfuge, denial of service and all of the vulnerabilities that networked computers must face. In our opinion, for the concept of virtual institutes to be successful and useful, their operations and services must be protected from the threats in the cyber environment. A key to developing the required protection is the development and promulgation of standards for cyber security. In this paper, we discuss the types of cyber standards that are required, how new internet technologies can be exploited and can benefit the promulgation, development, maintenance, and robustness of the standards. This paper is organized as follows. Section One introduces the concept of the virtual institutes, the expected benefits, and the motivation for our research and for research in this area. Section Two presents background material and a discussion of topics related to VIs, uman behavior and cultural modeling, and network-centric warfare. Section Three contains a discussion of the

  2. [Issues related to long-term asbestos use and manufacture].

    PubMed

    Trosić, Ivancica

    2009-11-01

    Extensive measures to ban mining, manufacture, use, and trade of asbestos and asbestos materials have been taken worldwide. In this century asbestos will continue to be an economic, industrial, health, social, and environmental issue. Five thousand products that are still in use have been inherited from a century of asbestos processing. In 1999, the EU member states decided to take steps that would eventually terminate the use of asbestos. At the same time, about 4000 t of asbestos had been imported to Croatia every year. EU member states started to enforce asbestos ban in 2005. This encouraged the Croatian Ministry of Health and Social Welfare to issue a list of toxicants whose manufacture, trade, and use were banned, and which included asbestos and asbestos products. In 2007, several national acts came to force regulating protection of workers occupationally exposed to asbestos. Asbestos is ubiquitous in the environment. It has been released from construction materials during renovations, demolitions, maintenance, and other building activities. It is released by drilling, blowing, demolishing, loading, transport, and improper storage of asbestos materials. Asbestos was often used for insulation. It was favoured for its resistance to heat, fire, moisture, noise, electricity, friction, and fraying. Materials used for firefighting, insulation, protection from noise, and construction frequently contain one or more types of asbestos. Landfills present a particular problem, since asbestos materials can not be recognised macroscopically. Asbestos can be identified by standardised polarising microscopy. This raises the need for education, because human exposure should be kept as low as possible to prevent the development of asbestos-related diseases. PMID:20853772

  3. Invited review: gender issues related to spaceflight: a NASA perspective.

    PubMed

    Harm, D L; Jennings, R T; Meck, J V; Powell, M R; Putcha, L; Sams, C P; Schneider, S M; Shackelford, L C; Smith, S M; Whitson, P A

    2001-11-01

    This minireview provides an overview of known and potential gender differences in physiological responses to spaceflight. The paper covers cardiovascular and exercise physiology, barophysiology and decompression sickness, renal stone risk, immunology, neurovestibular and sensorimotor function, nutrition, pharmacotherapeutics, and reproduction. Potential health and functional impacts associated with the various physiological changes during spaceflight are discussed, and areas needing additional research are highlighted. Historically, studies of physiological responses to microgravity have not been aimed at examining gender-specific differences in the astronaut population. Insufficient data exist in most of the discipline areas at this time to draw valid conclusions about gender-specific differences in astronauts, in part due to the small ratio of women to men. The only astronaut health issue for which a large enough data set exists to allow valid conclusions to be drawn about gender differences is orthostatic intolerance following shuttle missions, in which women have a significantly higher incidence of presyncope during stand tests than do men. The most common observation across disciplines is that individual differences in physiological responses within genders are usually as large as, or larger than, differences between genders. Individual characteristics usually outweigh gender differences per se. PMID:11641383

  4. Invited review: gender issues related to spaceflight: a NASA perspective

    NASA Technical Reports Server (NTRS)

    Harm, D. L.; Jennings, R. T.; Meck, J. V.; Powell, M. R.; Putcha, L.; Sams, C. P.; Schneider, S. M.; Shackelford, L. C.; Smith, S. M.; Whitson, P. A.

    2001-01-01

    This minireview provides an overview of known and potential gender differences in physiological responses to spaceflight. The paper covers cardiovascular and exercise physiology, barophysiology and decompression sickness, renal stone risk, immunology, neurovestibular and sensorimotor function, nutrition, pharmacotherapeutics, and reproduction. Potential health and functional impacts associated with the various physiological changes during spaceflight are discussed, and areas needing additional research are highlighted. Historically, studies of physiological responses to microgravity have not been aimed at examining gender-specific differences in the astronaut population. Insufficient data exist in most of the discipline areas at this time to draw valid conclusions about gender-specific differences in astronauts, in part due to the small ratio of women to men. The only astronaut health issue for which a large enough data set exists to allow valid conclusions to be drawn about gender differences is orthostatic intolerance following shuttle missions, in which women have a significantly higher incidence of presyncope during stand tests than do men. The most common observation across disciplines is that individual differences in physiological responses within genders are usually as large as, or larger than, differences between genders. Individual characteristics usually outweigh gender differences per se.

  5. Sexuality Education Issues and Students Statused Severely Mentally Impaired Regardless of Additional Handicaps.

    ERIC Educational Resources Information Center

    Heler, Ann

    This monograph considers issues in the training of sexuality skills in students with severe mental retardation. An introduction stresses the importance of such skills for these students. A profile of 12 common characteristics of this population and a summary of human commonalities precede the body of the guide. Common manifestations of sexuality…

  6. Considerations of Additional Stressors and Developmental Issues for Gay, Lesbian, Bisexual, and Transgender College Students

    ERIC Educational Resources Information Center

    Zubernis, Lynn; Snyder, Matthew

    2007-01-01

    At some point every college freshman asks "Am I okay?" or "Am I normal?" Helping students answer this question is a familiar part of college counseling. However, this task becomes more complicated when students who are gay, lesbian, bisexual, transgender (GLBT), or questioning their sexuality seek counseling. The universal issues which all college…

  7. Material issues relating to high power spallation neutron sources

    NASA Astrophysics Data System (ADS)

    Futakawa, M.

    2015-02-01

    Innovative researches using neutrons are being performed at the Materials and Life Science Experimental Facility (MLF) at the Japan Proton Accelerator Research Complex (J-PARC), in which a mercury target system is installed for MW-class pulse spallation neutron sources. In order to produce neutrons by the spallation reaction, proton beams are injected into the mercury target. At the moment, when the intense proton beam hits the target, pressure waves are generated in mercury because of the abrupt heat deposition. The pressure waves interact with the target vessel, leading to negative pressure that may cause cavitation along the vessel wall, i.e. on the interface between liquid and solid metals. On the other hand, the structural materials are subjected to irradiation damage due to protons and neutrons, very high cycle fatigue damages and so-called "liquid metal embrittlement". That is, the structural materials must be said to be exposed to the extremely severe environments. In the paper, research and development relating to the material issues in the high power spallation neutron sources that has been performed so far at J-PARC is summarized.

  8. Do medical students require education on issues related to plagiarism?

    PubMed

    Varghese, Joe; Jacob, Molly

    2015-01-01

    In the course of our professional experience, we have seen that many medical students plagiarise. We hypothesised that they do so out of ignorance and that they require formal education on the subject. With this objective in mind, we conducted a teaching session on issues related to plagiarism. As a part of this, we administered a quiz to assess their baseline knowledge on plagiarism and a questionnaire to determine their attitudes towards it. We followed this up with an interactive teaching session, in which we discussed various aspects of plagiarism. We subjected the data obtained from the quiz and questionnaire to bivariate and multivariate analysis. A total of 423 medical students participated in the study. Their average score for the quiz was 4.96±1.67 (out of 10). Age, gender and years in medical school were not significantly associated with knowledge regarding plagiarism. The knowledge scores were negatively correlated with permissive attitudes towards plagiarism and positively correlated with attitudes critical of the practice. Men had significantly higher scores on permissive attitudes compared to women . In conclusion, we found that the medical students' knowledge regarding plagiarism was limited. Those with low knowledge scores tended to have permissive attitudes towards plagiarism and were less critical of the practice. We recommend the inclusion of formal instruction on this subject in the medical curriculum, so that this form of academic misconduct can be tackled. PMID:25671582

  9. Relating realist metatheory to issues of gender and mental health.

    PubMed

    Bergin, M; Wells, John S G; Owen, Sara

    2010-06-01

    This paper seeks to advance the debate that considers critical realism as an alternative approach for understanding gender and mental health and its relatedness to mental health research and practice. The knowledge base of how 'sex' and 'gender' affect mental health and illness is expanding. However, the way we conceptualize gender is significant and challenging as quite often our ability to think about 'gender' as independent of 'sex' is not common. The influences and interplay of how sex (biological) and gender (social) affect mental health and illness requires consideration. Critical realism suggests a shared ontology and epistemology for the natural and social sciences. While much of the debate surrounding gender is guided within a constructivist discourse, an exploration of the concept 'gender' is reflected on and some key realist propositions are considered for mental health research and practice. This is achieved through the works of some key realist theorists. Critical realism offers potential for research and practice in relation to gender and mental health because it facilitates changes in our understanding, while simultaneously, not discarding that which is already known. In so doing, it allows the biological (sex) and social (gender) domains of knowledge for mental health and illness to coexist, without either being reduced to or defined by the other. Arguably, greater depth and explanations for gender and mental health issues are presented within a realist metatheory. PMID:20584241

  10. Ethical issues relating to reproduction control and women's health.

    PubMed

    Schenker, J G; Eisenberg, V H

    1997-07-01

    There are many ethical aspects which derive from the application of reproduction control in women's health. Women's health can be enhanced if women are given the opportunity to make their own reproduction choices about sex, contraception, abortion and application of reproductive technologies. The main issues that raise ethical dilemmas following the development of assisted reproduction techniques are: the right to procreate or reproduce; the process of in vitro fertilization itself-is it morally acceptable to interfere in the reproduction process?; the moral status of the embryo; the involvement of a third party in the reproductive process by genetic material donation; the practice of surrogacy, cryopreservation of pre-embryos; genetic manipulation; experiments on pre-embryos, etc. Induced abortion raises ethical issues related to the rights of the woman versus the rights of the fetus. For those who consider life to begin at conception abortion always equals murder and is therefore forbidden. Those who believe in the absolute autonomy of the woman over her body take the other extreme approach. The discussion surrounding abortion usually centers on whether it should be legal or illegal. Access to safe abortion is critical to the health of women and to their autonomy. The development of new effective contraceptive methods has a profound impact on women's lives. By the use of contraception it is possible to lessen maternal, infant and child mortality and to reduce the prevalence of sexually transmitted diseases. Research and development of new effective reversible contraceptives for women and men is needed. Dissemination of information about the safety and effectiveness of contraceptive methods is of great importance. Female genital mutilation is still practiced worldwide due to customs and tradition among various ethnic groups. The procedure is considered to be medically detrimental to the physical and mental health of women and girls, and is considered by many as

  11. Cabin Safety Issues Related to Pre-Departure and Inflight Issues

    NASA Technical Reports Server (NTRS)

    Connell, Linda

    2014-01-01

    The Aviation Safety Reporting System (ASRS) in a partnership between the National Aeronautics and Space Administration (NASA), the Federal Aviation Administration (FAA), participating carriers, and labor organizations. It is designed to improve the National Airspace System by collecting and studying reports detailing unsafe conditions and events in the aviation industry. Employees are able to report safety issues or concerns with confidentiality and without fear of discipline. Safety reports highlighting the human element in cabin safety issues and concerns.

  12. Damage Tolerance Issues as Related to Metallic Rotorcraft Dynamic Components

    NASA Technical Reports Server (NTRS)

    Everett, R. A., Jr.; Elber, W.

    1999-01-01

    In this paper issues related to the use of damage tolerance in life managing rotorcraft dynamic components are reviewed. In the past, rotorcraft fatigue design has combined constant amplitude tests of full-scale parts with flight loads and usage data in a conservative manner to provide "safe life" component replacement times. In contrast to the safe life approach over the past twenty years the United States Air Force and several other NATO nations have used damage tolerance design philosophies for fixed wing aircraft to improve safety and reliability. The reliability of the safe life approach being used in rotorcraft started to be questioned shortly after presentations at an American Helicopter Society's specialist meeting in 1980 showed predicted fatigue lives for a hypothetical pitch-link problem to vary from a low of 9 hours to a high in excess of 2594 hours. This presented serious cost, weight, and reliability implications. Somewhat after the U.S. Army introduced its six nines reliability on fatigue life, attention shifted towards using a possible damage tolerance approach to the life management of rotorcraft dynamic components. The use of damage tolerance in life management of dynamic rotorcraft parts will be the subject of this paper. This review will start with past studies on using damage tolerance life management with existing helicopter parts that were safe life designed. Also covered will be a successful attempt at certifying a tail rotor pitch rod using damage tolerance, which was designed using the safe life approach. The FAA review of rotorcraft fatigue design and their recommendations along with some on-going U.S. industry research in damage tolerance on rotorcraft will be reviewed.

  13. Damage Tolerance Issues as Related to Metallic Rotorcraft Dynamic Components

    NASA Technical Reports Server (NTRS)

    Everett, R. A., Jr.; Elber, W.

    2005-01-01

    In this paper issues related to the use of damage tolerance in life managing rotorcraft dynamic components are reviewed. In the past, rotorcraft fatigue design has combined constant amplitude tests of full-scale parts with flight loads and usage data in a conservative manner to provide "safe life" component replacement times. In contrast to the safe life approach over the past twenty years the United States Air Force and several other NATO nations have used damage tolerance design philosophies for fixed wing aircraft to improve safety and reliability. The reliability of the safe life approach being used in rotorcraft started to be questioned shortly after presentations at an American Helicopter Society's specialist meeting in 1980 showed predicted fatigue lives for a hypothetical pitch-link problem to vary from a low of 9 hours to a high in excess of 2594 hours. This presented serious cost, weight, and reliability implications. Somewhat after the U.S. Army introduced its six nines reliability on fatigue life, attention shifted towards using a possible damage tolerance approach to the life management of rotorcraft dynamic components. The use of damage tolerance in life management of dynamic rotorcraft parts will be the subject of this paper. This review will start with past studies on using damage tolerance life management with existing helicopter parts that were safe life designed. Also covered will be a successful attempt at certifying a tail rotor pitch rod using damage tolerance, which was designed using the safe life approach. The FAA review of rotorcraft fatigue design and their recommendations along with some on-going U.S. industry research in damage tolerance on rotorcraft will be reviewed. Finally, possible problems and future needs for research will be highlighted.

  14. 42 CFR 130.24 - What additional documentation may the Secretary require to resolve eligibility or payment issues?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false What additional documentation may the Secretary require to resolve eligibility or payment issues? 130.24 Section 130.24 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES COMPASSIONATE PAYMENTS RICKY RAY HEMOPHILIA RELIEF...

  15. 42 CFR 130.24 - What additional documentation may the Secretary require to resolve eligibility or payment issues?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false What additional documentation may the Secretary require to resolve eligibility or payment issues? 130.24 Section 130.24 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES COMPASSIONATE PAYMENTS RICKY RAY HEMOPHILIA RELIEF...

  16. 42 CFR 130.24 - What additional documentation may the Secretary require to resolve eligibility or payment issues?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false What additional documentation may the Secretary require to resolve eligibility or payment issues? 130.24 Section 130.24 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES COMPASSIONATE PAYMENTS RICKY RAY HEMOPHILIA RELIEF...

  17. 42 CFR 130.24 - What additional documentation may the Secretary require to resolve eligibility or payment issues?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false What additional documentation may the Secretary require to resolve eligibility or payment issues? 130.24 Section 130.24 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES COMPASSIONATE PAYMENTS RICKY RAY HEMOPHILIA RELIEF...

  18. 42 CFR 130.24 - What additional documentation may the Secretary require to resolve eligibility or payment issues?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false What additional documentation may the Secretary require to resolve eligibility or payment issues? 130.24 Section 130.24 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES COMPASSIONATE PAYMENTS RICKY RAY HEMOPHILIA RELIEF...

  19. 41 CFR 102-5.25 - What additional guidance concerning home-to-work transportation should Federal agencies issue?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What additional guidance concerning home-to-work transportation should Federal agencies issue? 102-5.25 Section 102-5.25 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION GENERAL...

  20. 16 CFR 456.5 - Rules applicable to prescriptions for contact lenses and related issues.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... contact lenses and related issues. Rules applicable to prescriptions for contact lenses and related issues may be found at 16 CFR part 315 (Contact Lens Rule). ... contact lenses and related issues. 456.5 Section 456.5 Commercial Practices FEDERAL TRADE COMMISSION...

  1. 16 CFR 456.5 - Rules applicable to prescriptions for contact lenses and related issues.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... contact lenses and related issues. Rules applicable to prescriptions for contact lenses and related issues may be found at 16 CFR part 315 (Contact Lens Rule). ... contact lenses and related issues. 456.5 Section 456.5 Commercial Practices FEDERAL TRADE COMMISSION...

  2. 16 CFR 456.5 - Rules applicable to prescriptions for contact lenses and related issues.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... contact lenses and related issues. Rules applicable to prescriptions for contact lenses and related issues may be found at 16 CFR part 315 (Contact Lens Rule). ... contact lenses and related issues. 456.5 Section 456.5 Commercial Practices FEDERAL TRADE COMMISSION...

  3. 16 CFR 456.5 - Rules applicable to prescriptions for contact lenses and related issues.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... contact lenses and related issues. Rules applicable to prescriptions for contact lenses and related issues may be found at 16 CFR part 315 (Contact Lens Rule). ... contact lenses and related issues. 456.5 Section 456.5 Commercial Practices FEDERAL TRADE COMMISSION...

  4. 16 CFR 456.5 - Rules applicable to prescriptions for contact lenses and related issues.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... contact lenses and related issues. Rules applicable to prescriptions for contact lenses and related issues may be found at 16 CFR part 315 (Contact Lens Rule). ... contact lenses and related issues. 456.5 Section 456.5 Commercial Practices FEDERAL TRADE COMMISSION...

  5. ROV intervention issues relating to pipelay operations in ultra deepwater

    SciTech Connect

    Mansfield, S.E.; McCoy, R.W.

    1994-12-31

    Recently, there has been a rapid increase in the water depths for some of the development projects of oil and gas fields. Not just in the installation of producing facilities, but of the transportation infrastructure. While ROVs are used extensively in support of deepwater pipelay operations, with the recent advances in J-Lay operations and the investigation into projects which may take this method to what is now being called ``ultra deepwater`` (i.e. 10,000 feet), there are new issues which must be addressed for continued ROV intervention to be successful. This paper will attempt to bring forth some of those issues and offer some potential solutions. It is necessary to begin thinking of these potential problem areas, as the solutions could impact the economics of the projects. These issues may well begin to influence the way the ROV industry further develops and refines it`s fleet to meet the needs of the authors clients in the future.

  6. College Students' Misconceptions of Environmental Issues Related to Global Warming.

    ERIC Educational Resources Information Center

    Groves, Fred H.; Pugh, Ava F.

    Students are currently exposed to world environmental problems--including global warming and the greenhouse effect--in science classes at various points during their K-12 and college experience. However, the amount and depth of explosure to these issues can be quite variable. Students are also exposed to sources of misinformation leading to…

  7. Safety, Efficacy, and Legal Issues Related to Dietary Supplements

    ERIC Educational Resources Information Center

    Powers, Michael

    2004-01-01

    This article focuses on the effects of dietary supplements on collegiate and adult populations. Anabolic steroids, amphetamines, and other drugs have been used for decades to improve athletic performance. However, the legal issues and dangers associated with these drugs have resulted in reluctance by many athletes to use them. Because dietary…

  8. Methodological issues in HIV-related social research in Nigeria.

    PubMed

    Erinosho, Olayiwola; Joseph, Richard; Isiugo-Abanihe, Uche; Dike, Nkem; Aderinto, Adeyinka A

    2013-12-01

    This paper is about methodological issues in a community-wide study in Nigeria on an infectious disease, namely HIV/AIDS. The study was designed to ascertain the risk factors that contribute to the spread of HIV/AIDS and how that can be tackled in order to bring about behavioural change. The research team believed at the onset that a study on the interplay between HIV/AIDS and sensitive issues like sexual mores and sexuality requires much more than a straightjacket social science method, such as simply doing a cross-section study and/or using interview schedule. This paper reviews the essence of cross-disciplinary approach; team building; as well as the use of a non-participatory observational approach in data collection. It also shows why ample consideration was given to ethical issues which are often glossed over in social research in developing countries. The lessons from the study underscore the methodological imperatives in social research that focus on sensitive issues in largely non-literate context like Nigeria. Although there are formidable challenges in community-based studies in largely non-literate societies, nevertheless they could easily be surmounted if there are ample time and resources to navigate the various sticking points. PMID:24689326

  9. Television Coverage of Issues Related to Global Education in Greece.

    ERIC Educational Resources Information Center

    Kostoulas-Makrakis, Nelly; Makrakis, Vasilis

    2000-01-01

    Investigated the extent to which 10 top-ranked global issues were covered on six popular Greek television stations, examining patterns in headline content and program descriptions from a television guide magazine. Results found that the priority of commercial criteria dominated over quality, especially in privately operated stations. There was a…

  10. Ecological Issues Related to Children's Health and Safety

    ERIC Educational Resources Information Center

    Aldridge, Jerry; Kohler, Maxie

    2009-01-01

    Issues concerning the health and safety of children and youth occur at multiple levels. Bronfenbrenner (1995) proposed an ecological systems approach in which multiple systems interact to enhance or diminish children's development. The same systems are at work in health promotion. The authors present and review articles that reflect the multiple…

  11. Issues related to SPR joints subjected to fatigue loads

    NASA Astrophysics Data System (ADS)

    De Luca, A.; Senatore, F.; Greco, A.

    2016-05-01

    SPR joints will represent an alternative solution to spot welding in automotive field. However, their fatigue behavior shows several critical issues. After a brief introduction of this new solution, different crack modes are described, emphasizing the parameters that characterize them, i.e. the applied loads, the geometry of the joint and other phenomenon as fretting, vibration and corrosion.

  12. Contextual Issues Related to Aboriginal Children's Mathematical Learning.

    ERIC Educational Resources Information Center

    Howard, Peter

    This paper focuses on contextual issues arising during an ethnographic study of mathematics instruction for Aboriginal children in New South Wales, Australia. Conversational interviews with Aboriginal children in grades 5-6, Aboriginal parents, and Aboriginal and non-Aboriginal teachers and staff identified context as 1 of 17 core categories of…

  13. Teacher-Student Sexual Relations: Key Risks and Ethical Issues

    ERIC Educational Resources Information Center

    Sikes, Pat

    2010-01-01

    Researching actual or purported sexual contact between teachers and students raises many difficult ethical issues, questions and dilemmas, which may help to explain why few have ventured into the field. This experientially based paper addresses key problem areas under the headings of: the ethics of researching a sensitive taboo topic; the ethics…

  14. Contemporary Issues in U.S.-Mexico Relations, Part 2.

    ERIC Educational Resources Information Center

    Cheng, Amy; Kim, Pearl; Lai, Selena; Mukai, Gary; Nunez, Lucia; Valadez, Martin

    The lessons in this 3-part series are intended to provide students with a basic understanding of the relationship between the United States and Mexico, with emphasis on multiple perspectives, conflict and cooperation, and interdependence. This curriculum unit, Part 2, examines three contemporary issues: immigration, the North American Free Trade…

  15. Relating Social Inclusion and Environmental Issues in Botanic Gardens

    ERIC Educational Resources Information Center

    Vergou, Asimina; Willison, Julia

    2016-01-01

    Botanic gardens have been evolving, responding to the changing needs of society, from their outset as medicinal gardens of monasteries and university gardens to more recently as organizations that contribute to the conservation of plant genetic resources. Considering that social and environmental issues are deeply intertwined and cannot be tackled…

  16. CSI related dynamics and control issues in space robotics

    NASA Technical Reports Server (NTRS)

    Schmitz, Eric; Ramey, Madison

    1993-01-01

    The research addressed includes: (1) CSI issues in space robotics; (2) control of elastic payloads, which includes 1-DOF example, and 3-DOF harmonic drive arm with elastic beam; and (3) control of large space arms with elastic links, which includes testbed description, modeling, and experimental implementation of colocated PD and end-point tip position controllers.

  17. Improvement of pattern collapse issue by additive-added D.I. water rinse process

    NASA Astrophysics Data System (ADS)

    Tanaka, Keiichi; Naito, Ryoichiro; Kitada, Tomohiro; Kiba, Yukio; Yamada, Yoshiaki; Kobayashi, Masakazu; Ichikawa, Hiroyuki

    2003-06-01

    Reduction of critical dimension in lithography technology is aggressively promoted. At the same time, further resist thickness reduction is being pursued to increase the resolution capabilities of resist. However, thin film has its limitation because of etch requirements etc. As that result, the promotion of reduction results in increasing the aspect ratio, which leads to pattern collapse. It is well known that at drying step in developing process the capillary effect operates the photoresist pattern. If the force of the capillary effect is greater than the aggregation force of the resist pattern, the pattern collapse is generated. And the key parameters of the capillary effect are the space width between patterns, the aspect ratio, the contact angle of the D.I water rinse and the surface tension of rinse solution. Among these parameters the surface tension of rinse solution can be controlled by us. On the other hand, we've already reported that the penetration of TMAH and D.I water into the resist plays an important role on the lithographic latitude. For example, when we use the resist which TMA ion can be easily diffuse into, D.I water and TMA ion which are penetrated in the resist decreases the aggregation force of resist pattern and causes the pattern collapse even by the weak force against resist pattern. These results indicate that the swelling of photoresist by TMA ion and water is very important factor for controlling the pattern collapse. Currently, two methods are mainly tried to reduce the surface tension of rinse solution: SCF (Super Critical Fluid) and addition of additive to D.I water rinse. We used the latter method this time, because this technique has retrofittability and not special tool. And in this evaluation, we found that the degree of suppressing pattern collapse depends on the additive chemistry or formulation. With consideration given to process factors such as above, we investigated what factors contribute to suppressing pattern collapse

  18. Chlorofluorocarbon environmental issues related to conservation acquisition in commercial buildings

    SciTech Connect

    Marseille, T.J.; Baechler, M.C.

    1990-09-01

    Recent scientific evidence strongly suggests that the release of large quantities of chlorofluorocarbon (CFC) gases into the atmosphere will result in environmentally harmful long-term effects. Because of those effects, a massive worldwide effort is currently under way to ban their use. At request of the Bonneville Power Administration, the Pacific Northwest Laboratory conducted a literature search to identify the issues surrounding the CFC phaseout. The search was focused on how these issues impact the commercial building sector. Information was obtained that describes: How the release of CFCs into the atmosphere may affect the global environment; legislative and regulatory programs initiated to restrict CFCs; potential impacts the reduced CFC supply will have on commercial buildings; the most promising CFC substitute technologies; and the potential costs of CFC restriction. 11 refs., 2 tabs.

  19. Ethical issues regarding related and nonrelated living organ donors.

    PubMed

    Testa, Giuliano

    2014-07-01

    The ethics of the clinical practice of transplanting human organs for end-stage organ disease is a fascinating topic. Who is the "owner" of the transplantable organs of a deceased, brain-dead patient? Who should have a right to receive these organs? Who set the boundaries between a living donor's autonomy and a "paternalistic" doctor? What constitutes a proper consent? These questions are only some of the ethical issues that have been discussed in the last 60 years. All of these ethical issues are intensified by the fact that supply of human organs does not match demand, and that, as a consequence, living-donor organ transplantation is widely utilized. The aim of this article is not to be exhaustive but to present the general ethical principles of beneficence, nonmaleficence, and justice as applied to organ transplantation. Moreover, the topic of reimbursement for organ donation is also discussed. PMID:24705806

  20. System Issues Related to Implementing on the Internet

    NASA Technical Reports Server (NTRS)

    Mackey, William; Bagg, Thomas C., III

    1999-01-01

    Implementing capabilities on the World Wide Web should never be taken lightly. A good systems engineer is able to examine such implementations from all points of view, including political, legal, security, access, technical deployment, and quality. The evacuation discussed in this paper was conducted to ensure that the National Aeronautics and Space Administration (NASA) was proceeding in a correct direction by implementing RECALL a Lessons Learned System on the Web and, subsequently, did so successfully. The systems approach extended well beyond technical implementation to several issue that are not often addressed by an implementation team. The resulting evaluation increased the team's sensitivity to such issues and, in fact, the authors believe that the evaluation provided as much benefit as the system itself.

  1. Policy issues related to prospective payment for pediatric hospitalization

    PubMed Central

    Payne, Susan M. C.; Restuccia, Joseph D.

    1987-01-01

    Children's hospitals have been excluded from the Medicare prospective payment system (PPS) because of concerns over the applicability of the DRG case-mix system and PPS payment weights to pediatric hospitalization. Nevertheless, DRG-based payment systems are being adopted by State Medicaid agencies and private third-party payers, and the Health Care Financing Administration has been mandated to report to Congress on the feasibility of including children's hospitals in the Federal PPS. This article summarizes policy research on this issue and discusses options in the design of prospective payment systems for pediatric hospitalization. PMID:10312273

  2. Four issues in undernutrition-related health impact modeling

    PubMed Central

    2013-01-01

    Undernutrition modeling makes it possible to evaluate the potential impact of such events as a food-price shock or harvest failure on the prevalence and severity of undernutrition. There are, however, uncertainties in such modeling. In this paper we discuss four methodological issues pertinent to impact estimation: (1) the conventional emphasis on energy intake rather than dietary quality; (2) the importance of the distribution of nutrient intakes; (3) the timing of both the ‘food shock’ and when the response is assessed; and (4) catch-up growth and risk accumulation. PMID:24073617

  3. Policy issues related to prospective payment for pediatric hospitalization.

    PubMed

    Payne, S M; Restuccia, J D

    1987-01-01

    Children's hospitals have been excluded from the Medicare prospective payment system (PPS) because of concerns over the applicability of the DRG case-mix system and PPS payment weights to pediatric hospitalization. Nevertheless, DRG-based payment systems are being adopted by State Medicaid agencies and private third-party payers, and the Health Care Financing Administration has been mandated to report to Congress on the feasibility of including children's hospitals in the Federal PPS. This article summarizes policy research on this issue and discusses options in the design of prospective payment systems for pediatric hospitalization. PMID:10312273

  4. Dealing with quantum weirdness: Holism and related issues

    SciTech Connect

    Elby, A.R.

    1995-12-01

    Various issues are discussed in interpretation of quantum mechanics. All these explorations point toward the same conclusion, that some systems are holistically connected, i.e., some composite systems have properties that cannot, even in principle, be reduced to the properties of its subsystems. This is argued to be the central metaphysical lesson of quantum theory; this will remain pertinent even if quantum mechanics gets replaced by a superior theory. Chap. 2 discusses nonlocality and rules out hidden-variable theories that approximately reproduce the perfect correlations of quantum mechanics, as well as theories that obey locality conditions weaker than those needed to derive Bell`s inequality. Chap. 3 shows that SQUID experiments can rule out non-invasive measurability if not macrorealism. Chap. 4 looks at interpretational issues surrounding decoherence, the dissipative interaction between a system and its environment. Decoherence klcan help ``modal`` interpretations pick out the desired ``preferred`` basis. Chap. 5 explores what varieties of causation can and cannot ``explain`` EPR correlations. Instead of relying on ``watered down`` causal explanations, we should instead develop new, holistic explanatory frameworks.

  5. Radiation protection issues related to Canadian museum operations.

    PubMed

    Waller, Edward J; Cole, David; Jamieson, Terry

    2008-02-01

    Museums in Canada have been found to possess radioactive items. The origin of the radiation can be broadly categorized as either natural (generally, radioactive ores) or anthropogenic (generally, luminous gauges). Radioluminescent gauges, especially bearing radium (226Ra), can also generate significant radiation fields. This is especially true if many gauges are located in close proximity. In addition, the radon may out-gas from these gauges, and generate a loose contamination problem in enclosed spaces (such as display cases). Radioactive ores, bearing naturally occurring uranium and thorium, can generate radiation fields many times greater than the ambient background levels. In addition, they will increase the ambient radon level and potentially generate loose contamination. In this paper, we discuss the specific results of radiological decommissioning at three museums: the National Air Force Museum of Canada (Trenton, Ontario); the Quebec Air and Space Museum (Montreal, PQ); and the Canadian Museum of Nature (Aylmer, PQ). In addition, a radiological survey performed at Canadian Forces Detachment Mountain View (Mountain View, Ontario) of surplus aircraft is included. The primary conclusion is that museums holding radioactive materials may have detectable levels of loose Ra and progeny contamination. They, therefore, have a requirement to be surveyed for loose contamination periodically with the potential for periodic decontamination caused by radon out-gassing. In addition, public access to displays bearing radioactive material should generally be restricted, and comprehensive radiation safety and security programs at museum facilities should be developed and enacted. PMID:18192793

  6. Safety issues related to synthetic-fuels facilities

    NASA Astrophysics Data System (ADS)

    The design, siting, construction, operation, and decommissioning of coal gasification, coal liquefaction, and oil shale facilities could present safety risks both to synfuels workers and to the environmental system unless careful controls are exercised. Many of these hazards are expected to be similar to those associated with conventional mining, mineral processing, coking operations, and refining of petroleum. However, because of the chemical and physical properties of coal and shale and their products, the types of technologies to be employed, and the scales of their operations, it has been suggested that unconventional hazards may occur. Issues which summarize the deliverations and work of the Committee on Synthetic Fuels Facilities Safety in evaluating the various technologies and their potentials for unconventional safety hazards are described in Chapters 2 and 3 of the report.

  7. Issues related to criticality safety analysis for burnup credit applications

    SciTech Connect

    DeHart, M.D.; Parks, C.V.

    1995-12-01

    Spent fuel transportation and storage cask designs based on a burnup credit approach must consider issues that are not relevant in casks designed under a fresh fuel loading assumption. Parametric analyses are required to characterize the importance of fuel assembly and fuel cycle parameters on spent fuel composition and reactivity. Numerical models are evaluated to determine the sensitivity of criticality safety calculations to modeling assumptions. This paper discusses the results of studies to determine the effect of two important modeling assumptions on the criticality analysis of pressurized-water reactor (PWR) spent fuel: (1) the effect of assumed burnup history (i.e., specific power during and time-dependent variations in operational power) during depletion calculations, and (2) the effect of axial burnup distributions on the neutron multiplication factor calculated for a three-dimensional (3-D) conceptual cask design.

  8. Levothyroxine: therapeutic use and regulatory issues related to bioequivalence.

    PubMed

    Wartofsky, Leonard

    2002-06-01

    Levothyroxine is the overwhelming choice of clinicians for the treatment of hypothyroidism and for the suppression of goitre and thyroid nodules in selected cases. The monitoring of serum levels of thyroid stimulating hormone is necessary for appropriate dosage adjustment of levothyroxine. Levothyroxine has a narrow therapeutic index: both underdosage (subclinical hypothyroidism) and excessive dosage (subclinical hyperthyroidism) are associated with adverse symptoms and pathophysiological effects and are to be avoided. The consequent necessity for careful titration of doses has had an impact on the issue of switchability, or bioequivalence, of the various marketed levothyroxine products. In this article, the basis for concern about currently accepted standards of the FDA for pharmacological bioequivalence are examined in the context of levothyroxine. The history and status of the recent request by the FDA for a new drug application for all levothyroxine products, and its impact on the market leader Synthroid, is also discussed. PMID:12036412

  9. PRECISION MEASUREMENT OF MUON G-2 AND ACCELERATOR RELATED ISSUES

    SciTech Connect

    BROWN,H.N.; BUNCE,G.; CAREY,R.M.; CUSHMAN,P.; DANBY,G.T.; DEBEVEC,P.T.; DEILE,M.; DENG,H.; DENINGER,W.; DHAWAN,S.K.; ET AL; MENG,W.

    2001-09-21

    A precision measurement of the anomalous g value, a{sub {mu}}=(g-2)/2, for the positive muon has been made using high intensity protons available at the Brookhaven AGS. The result based on the 1999 data a{sub {mu}}=11659202(14)(6) x 10{sup 10} (1.3ppm) is in good agreement with previous measurements and has an error one third that of the combined previous data. The current theoretical value from the standard model is a{sub {mu}} (SM)=11659159.6(6.7) x 10{sup 10} (0.57 ppm) and differ by over 2.5 standard deviation with experiment. Issues with reducing systematic errors and enhancing the injection and storage efficiencies are discussed.

  10. Ethical issues relating to renal transplantation from prediabetic living donor

    PubMed Central

    2014-01-01

    Background In Mexico, diabetes mellitus is the main cause of end − stage kidney disease, and some patients may be transplant candidates. Organ supply is limited because of cultural issues. And, there is a lack of standardized clinical guidelines regarding organ donation. These issues highlight the tension surrounding the fact that living donors are being selected despite being prediabetic. This article presents, examines and discusses using the principles of non-maleficience, autonomy, justice and the constitutionally guaranteed right to health, the ethical considerations that arise from considering a prediabetic person as a potential kidney donor. Discussion Diabetes is an absolute contraindication for donating a kidney. However, the transplant protocols most frequently used in Mexico do not consider prediabetes as exclusion criteria. In prediabetic persons there are well known metabolic alterations that may compromise the long − term outcomes of the transplant if such donors are accepted. Even so, many of them are finally included because there are not enough donor candidates. Both, families and hospitals face the need to rapidly accept prediabetic donors before the clinical conditions of the recipient and the evolution of the disease exclude him/her as a transplant candidate; however, when using a kidney potentially damaged by prediabetes, neither the donor’s nor the recipient’s long term health is usually considered. Considering the ethical implication as well as the clinical and epidemiological evidence, we conclude that prediabetic persons are not suitable candidates for kidney donation. This recommendation should be taken into consideration by Mexican health institutions who should rewrite their transplant protocols. Summary We argue that the decision to use a kidney from a living donor known to be pre-diabetic or from those persons with family history of T2DM, obesity, hypertension, or renal failure, should be considered unethical in Mexico

  11. Could Talk Therapy Ease Chemo-Related Memory Issues?

    MedlinePlus

    ... of Health, the U.S. Department of Health and Human Services, or federal policy. More Health News on: Cancer Chemotherapy Cancer--Living with Cancer Memory Recent Health News Related MedlinePlus Health Topics Cancer ...

  12. A Survey of Solver-Related Geometry and Meshing Issues

    NASA Technical Reports Server (NTRS)

    Masters, James; Daniel, Derick; Gudenkauf, Jared; Hine, David; Sideroff, Chris

    2016-01-01

    There is a concern in the computational fluid dynamics community that mesh generation is a significant bottleneck in the CFD workflow. This is one of several papers that will help set the stage for a moderated panel discussion addressing this issue. Although certain general "rules of thumb" and a priori mesh metrics can be used to ensure that some base level of mesh quality is achieved, inadequate consideration is often given to the type of solver or particular flow regime on which the mesh will be utilized. This paper explores how an analyst may want to think differently about a mesh based on considerations such as if a flow is compressible vs. incompressible or hypersonic vs. subsonic or if the solver is node-centered vs. cell-centered. This paper is a high-level investigation intended to provide general insight into how considering the nature of the solver or flow when performing mesh generation has the potential to increase the accuracy and/or robustness of the solution and drive the mesh generation process to a state where it is no longer a hindrance to the analysis process.

  13. Current Issues in the Neurology and Genetics of Learning-Related Traits and Disorders: Introduction to the Special Issue.

    ERIC Educational Resources Information Center

    Gilger, Jeffrey W.

    2001-01-01

    This introductory article briefly describes each of the following eight articles in this special issue on the neurology and genetics of learning related disorders. It notes the greater appreciation of learning disability as a set of complex disorders with broad and intricate neurological bases and of the large individual differences in how these…

  14. Relating Work and Education. Current Issues in Higher Education 1977.

    ERIC Educational Resources Information Center

    Vermilye, Dyckman; Ferris, William, Eds.

    The relationship between education and work is examined in relation to improving the quality of life. Part one provides a philosophical framework in which the authors reject the idea that work and education should be oriented toward porducing goods and making money, but should contribute to the growth and development of the workers. Part two…

  15. 21 CFR 71.22 - Deception as a basis for refusing to issue regulations; deceptive use of a color additive for...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... regulations; deceptive use of a color additive for which a regulation has issued. 71.22 Section 71.22 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL COLOR ADDITIVE...; deceptive use of a color additive for which a regulation has issued. The Commissioner shall refuse to...

  16. 21 CFR 71.22 - Deception as a basis for refusing to issue regulations; deceptive use of a color additive for...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... regulations; deceptive use of a color additive for which a regulation has issued. 71.22 Section 71.22 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL COLOR ADDITIVE...; deceptive use of a color additive for which a regulation has issued. The Commissioner shall refuse to...

  17. Implementation of the NCSS Guidelines for Teaching Science-Related Social Issues: Exemplar Lessons.

    ERIC Educational Resources Information Center

    Otto, Robert A., Ed.

    This document contains the Guidelines for Teaching Science-Related Social Issues adopted in 1982 by the National Council for the Social Studies and 10 examplar lessons each keyed to particular guidelines and drawing upon contemporary issues. The premise upon which the guidelines are based is that science is a social issue and that the examination…

  18. Firearm-related injuries in Canada: issues for prevention.

    PubMed Central

    Chapdelaine, A; Samson, E; Kimberley, M D; Viau, L

    1991-01-01

    We reviewed the available data on firearm-related injuries in Canada to suggest strategies for prevention in the context of the proposed amendments to the Criminal Code (Bill C-17) currently before Parliament. The risk of death from a firearm in Canada is equivalent to the risk of death from a motor vehicle crash. We discuss the risks associated with firearms with regard to suicides, homicides and "accidents." We also discuss the accessibility of firearms. This article builds upon a recently published update on the epidemiologic basis of the public health approach for the prevention of firearm-related injuries and deaths. The key to the etiologic approach to preventing such injuries and deaths is to view the incidents, regardless of their medicolegal circumstances, as having one factor in common: the discharge of a firearm. PMID:1933704

  19. Issues related to development of new antiseizure treatments.

    PubMed

    Wilcox, Karen S; Dixon-Salazar, Tracy; Sills, Graeme J; Ben-Menachem, Elinor; White, H Steve; Porter, Roger J; Dichter, Marc A; Moshé, Solomon L; Noebels, Jeffrey L; Privitera, Michael D; Rogawski, Michael A

    2013-08-01

    This report represents a summary of the discussions led by the antiseizure treatment working group of the International League Against Epilepsy (ILAE)/American Epilepsy Society (AES) Working Groups joint meeting in London (London Meeting). We review here what is currently known about the pharmacologic characteristics of current models of refractory seizures, both for adult and pediatric epilepsy. In addition, we address how the National Institute of Neurological Disorders and Stroke (NINDS)-funded Anticonvulsant Screening Program (ASP) is evolving to incorporate appropriate animal models in the search for molecules that might be sufficiently novel to warrant further pharmacologic development. We also briefly address what we believe is necessary, going forward, to achieve the goal of stopping seizures in all patients, with a call to arms for funding agencies, the pharmaceutical industry, and basic researchers. PMID:23909851

  20. Current Technologies and Related Issues for Mushroom Transformation

    PubMed Central

    Kim, Sinil; Ha, Byeong-Suk

    2015-01-01

    Mushroom transformation requires a series of experimental steps, including generation of host strains with a desirable selective marker, design of vector DNA, removal of host cell wall, introduction of foreign DNA across the cell membrane, and integration into host genomic DNA or maintenance of an autonomous vector DNA inside the host cell. This review introduces limitations and obstacles related to transformation technologies along with possible solutions. Current methods for cell wall removal and cell membrane permeabilization are summarized together with details of two popular technologies, Agrobacterium tumefaciens-mediated transformation and restriction enzyme-mediated integration. PMID:25892908

  1. Planetary protection issues related to human missions to Mars

    NASA Astrophysics Data System (ADS)

    Debus, A.; Arnould, J.

    2008-09-01

    In accordance with the United Nations Outer Space Treaties [United Nations, Agreement Governing the Activities of States on the Moon and Other Celestial Bodies, UN doc A/RES/34/68, resolution 38/68 of December 1979], currently maintained and promulgated by the Committee on Space Research [COSPAR Planetary Protection Panel, Planetary Protection Policy accepted by the COSPAR Council and Bureau, 20 October 2002, amended 24 March 2005, http://www.cosparhq.org/scistr/PPPolicy.htm], missions exploring the Solar system must meet planetary protection requirements. Planetary protection aims to protect celestial bodies from terrestrial contamination and to protect the Earth environment from potential biological contamination carried by returned samples or space systems that have been in contact with an extraterrestrial environment. From an exobiology perspective, Mars is one of the major targets, and several missions are currently in operation, in transit, or scheduled for its exploration. Some of them include payloads dedicated to the detection of life or traces of life. The next step, over the coming years, will be to return samples from Mars to Earth, with a view to increasing our knowledge in preparation for the first manned mission that is likely to take place within the next few decades. Robotic missions to Mars shall meet planetary protection specifications, currently well documented, and planetary protection programs are implemented in a very reliable manner given that experience in the field spans some 40 years. With regards to sample return missions, a set of stringent requirements has been approved by COSPAR [COSPAR Planetary Protection Panel, Planetary Protection Policy accepted by the COSPAR Council and Bureau, 20 October 2002, amended 24 March 2005, http://www.cosparhq.org/scistr/PPPolicy.htm], and technical challenges must now be overcome in order to preserve the Earth’s biosphere from any eventual contamination risk. In addition to the human dimension of

  2. Hospital Malnutrition Related to Fasting and Underfeeding: Is It an Ethical Issue?

    PubMed

    Arenas Moya, Diego; Plascencia Gaitán, Alejandra; Ornelas Camacho, Denisse; Arenas Márquez, Humberto

    2016-06-01

    Hospital malnutrition is a relevant clinical issue present in about 50% of patients that is associated with increased morbidity, mortality, and cost of care. Because of the relation of malnutrition with chronic and acute inflammatory processes secondary to disease, nutrition therapy is considered an important medical treatment. However, there is little discussion about the impact of another critical issue related to hospital malnutrition, that is, lack of appropriate food or nutrition therapy given to the patients. Unnecessary fasting practices and the use of inappropriate nutrition prescriptions result in underfeeding that can be a related or direct cause of hospital malnutrition, independent of disease or inflammatory state. Suboptimal prescription of oral, enteral, and parenteral nutrition should be analyzed and discussed from an ethical perspective since this practice has the potential to harm patients. In addition, absence or inadequate provision of nutrition may present barriers for improved patient outcomes and could be prevented by simply recognizing lack of knowledge, skills, or experience in nutrition and entrusting nutrition prescription to interdisciplinary teams with clinicians well prepared in nutrition sciences. This article reviews potential barriers to the prevention or treatment of hospital malnutrition and proposes specific actions that can help clinicians to overcome and implement optimal nutrition not just as medical therapy but also as a basic comfort care that may help patients nutritionally, clinically, physically, and emotionally. PMID:27208012

  3. Rearward Visibility Issues Related to Agricultural Tractors and Self-Propelled Machinery: Contributing Factors, Potential Solutions.

    PubMed

    Ehlers, S G; Field, W E

    2016-01-01

    As the size, complexity, and speed of agricultural tractors and self-propelled machinery have increased, so have the visibility-related issues, placing significant importance on the visual skills, alertness, and reactive abilities of the operator. Rearward movement of large agricultural equipment has been identified in the literature as causing both fatalities and injuries to bystanders who were not visible to the operator and damage to both the machine and stationary objects. The addition of monitoring assistance, while not a new concept, has advanced significantly, offering agricultural machinery operators greater options for increasing their awareness of the area surrounding the machine. In this research, we attempt to (1) identify and describe the key contributors to agricultural machinery visibility issues, i.e., operator-related and machine-related factors, and (2) enumerate and evaluate the potential solutions being offered that address these factors. Enhanced operator safety and efficiency should result from a better understanding of the efforts to solve the visibility problems inherent in large tractors and self-propelled agricultural machinery. PMID:27024992

  4. Plan for addressing issues relating to oil shale plant siting

    SciTech Connect

    Noridin, J. S.; Donovan, R.; Trudell, L.; Dean, J.; Blevins, A.; Harrington, L. W.; James, R.; Berdan, G.

    1987-09-01

    The Western Research Institute plan for addressing oil shale plant siting methodology calls for identifying the available resources such as oil shale, water, topography and transportation, and human resources. Restrictions on development are addressed: land ownership, land use, water rights, environment, socioeconomics, culture, health and safety, and other institutional restrictions. Descriptions of the technologies for development of oil shale resources are included. The impacts of oil shale development on the environment, socioeconomic structure, water availability, and other conditions are discussed. Finally, the Western Research Institute plan proposes to integrate these topics to develop a flow chart for oil shale plant siting. Western Research Institute has (1) identified relative topics for shale oil plant siting, (2) surveyed both published and unpublished information, and (3) identified data gaps and research needs. 910 refs., 3 figs., 30 tabs.

  5. Funerals and families: locating death as a relational issue.

    PubMed

    Woodthorpe, Kate; Rumble, Hannah

    2016-06-01

    Situated at the intersection of the Sociology of Death and Sociology of the Family, this paper argues that the organization and funding of funerals is an overlooked and available lens through which to examine cultural and political norms of familial obligation. Drawing on interviews with claimants to the Department for Work and Pensions' Social Fund Funeral Payment, the paper shows how both responsibility for the organization and payment of a funeral is assumed within families, and how at times this can be overridden by the state. In highlighting the tension between reflexive choice and political norms of family espoused in this policy context, it supports Gilding's () assertion that understanding family practice through reflexivity alone neglects the institutions and conventions within which 'doing' family takes place. In so doing, the paper further makes a case for families and relational negotiations and tensions to be more explicitly included within sociological understanding(s) of death more generally. PMID:27149075

  6. (Environmental issues related to hydroelectric development in the Unites States)

    SciTech Connect

    Hildebrand, S.G.

    1988-06-01

    The traveler delivered a report and met with principal scientists at UNESCO at the invitation of Mr. Nelson da Franca, Project Officer for the IHP. The traveler reviewed contributions to an IHP project from two scientists in Czechoslovakia and discussed the format of the final report on the project to be developed to be developed in early 1989. The traveler was briefed on the next phase of the IHP activities by several members of the staff of UNESCO and was invited to submit new projects related to energy and water to be considered at the Intergovernmental Council meeting of the IHP in June of 1988. This next phase of the IHP deals with water resources for sustainable development in a changing environment. Several potentially exciting opportunities for the Oak Ridge National Laboratory (ORNL) were identified.

  7. Accelerators for charged particle therapy: PAMELA and related issues

    NASA Astrophysics Data System (ADS)

    Peach, Ken

    2014-05-01

    Cancer is a dreadful disease that will affect one in three people at some point in their life; radiotherapy is used in more than half of all cancer treatment, and contributes about 40% to the successful treatment of cancer. Charged Particle Therapy uses protons and other light ions to deliver the lethal dose to the tumor while being relatively sparing of healthy tissue and, because of the finite range of the particles, is able to avoid giving any dose to vital organs. While there are adequate technologies currently available to deliver the required energies and fluxes, the two main technologies (cyclotrons and synchrotrons) have limitations. PAMELA (the Particle Accelerator for MEdicaLApplications) uses the newly-developed non-scaling Fixed Field Alternating Gradient accelerator concepts to deliver therapeutically relevant beams. The status of the development of the PAMELA conceptual design is discussed.

  8. Nutritional and growth issues related to child neglect.

    PubMed

    Black, Maureen M; Drennen, Chloe R

    2014-11-01

    Child neglect and obesity are major public health problems that undermine children's health and contribute to lifelong disparities. Most of the past research has focused on relations between child neglect and failure to thrive. This article finds that evidence linking child neglect with obesity is mixed. In a recent meta-analysis, five of the eight studies reviewed did not find an increased risk of obesity among neglected children. The case study and three longitudinal studies that reported a relationship between neglect and obesity were conducted among young children, and used caregiver or teacher/clinician definitions of neglect, rather than referrals to state protective service agencies. Dysregulation of the neuroendocrine system associated with neglect has been implicated, but further research is needed to understand the mechanisms that may increase children's risk for obesity. Findings suggest that under some conditions neglect may increase the risk for excessive weight gain, and that high body mass index may be an indicator of possible neglect. By exploring both possibilities, clinicians can promote children's healthy growth and development and prevent subsequent health disparities. PMID:25369579

  9. Breaking bad news: issues relating to nursing practice.

    PubMed

    Warnock, Clare

    2014-07-15

    The breaking of bad news was traditionally regarded to be the time when a doctor and nurse sat down with a patient and family members to provide information about, for example, a life-limiting diagnosis or a poor prognosis. However, breaking bad news is now generally accepted as a process, not a one-off event, and is considered to refer to any bad, sad or difficult information that alters patients' perceptions of their present and future. Nurses have an important role in the process of providing information and helping patients prepare for, receive, understand and cope with the bad news they have been given. This article aims to help nurses understand the process of breaking bad news and discuss the challenges and difficulties that nurses can face when they are involved with patients who have been given bad news. It also provides guidance with regard to preparing for breaking bad news, giving difficult information, responding to possible reactions, and supporting patients and their relatives after they have received bad news. PMID:25005417

  10. 77 FR 73586 - Further Inquiry Into Issues Related to Mobility Fund Phase II

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-11

    ...The Wireless Telecommunications Bureau and Wireline Competition Bureau (collectively, the Bureaus) seek further comment on specific issues relating to the implementation of Phase II of the Mobility Fund. The Bureaus also seek to develop a more comprehensive record on certain issues relating to the award of ongoing support for advanced mobile...

  11. 32 CFR 536.35 - Unique issues related to environmental claims.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 3 2011-07-01 2009-07-01 true Unique issues related to environmental claims... issues related to environmental claims. Claims for property damage, personal injury, or death arising in... reported by USARCS to the Environmental Law Division of the Army Litigation Center and the...

  12. 32 CFR 536.35 - Unique issues related to environmental claims.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Unique issues related to environmental claims... issues related to environmental claims. Claims for property damage, personal injury, or death arising in... reported by USARCS to the Environmental Law Division of the Army Litigation Center and the...

  13. 32 CFR 536.35 - Unique issues related to environmental claims.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 3 2013-07-01 2013-07-01 false Unique issues related to environmental claims... issues related to environmental claims. Claims for property damage, personal injury, or death arising in... reported by USARCS to the Environmental Law Division of the Army Litigation Center and the...

  14. 78 FR 17612 - Rules Relating to Additional Medicare Tax; Hearing Cancellation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-22

    ... public hearing that appeared in the Federal Register on Wednesday, December 5, 2012 (77 FR 72268... Internal Revenue Service 26 CFR Parts 1 and 31 RIN 1545-BK54 Rules Relating to Additional Medicare Tax...; relating to the Additional Hospital Insurance Tax on income above threshold amounts as added by...

  15. 31 CFR 561.204 - Additional petroleum-related sanctions on certain foreign financial institutions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Additional petroleum-related sanctions... TREASURY IRANIAN FINANCIAL SANCTIONS REGULATIONS Prohibitions § 561.204 Additional petroleum-related... Iran Sanctions Act of 1996 (Pub. L. 104-172) (50 U.S.C. 1701 note), as amended, are refined...

  16. 31 CFR 561.204 - Additional petroleum-related sanctions on certain foreign financial institutions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Additional petroleum-related sanctions... TREASURY IRANIAN FINANCIAL SANCTIONS REGULATIONS Prohibitions § 561.204 Additional petroleum-related... Iran Sanctions Act of 1996 (Pub. L. 104-172) (50 U.S.C. 1701 note), as amended, are refined...

  17. 48 CFR 1337.110-71 - Additional DOC clauses related to service contracting.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Additional DOC clauses related to service contracting. 1337.110-71 Section 1337.110-71 Federal Acquisition Regulations System....110-71 Additional DOC clauses related to service contracting. (a) Insert a clause...

  18. 48 CFR 1337.110-71 - Additional DOC clauses related to service contracting.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Additional DOC clauses related to service contracting. 1337.110-71 Section 1337.110-71 Federal Acquisition Regulations System....110-71 Additional DOC clauses related to service contracting. (a) Insert a clause...

  19. 48 CFR 1337.110-71 - Additional DOC clauses related to service contracting.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Additional DOC clauses related to service contracting. 1337.110-71 Section 1337.110-71 Federal Acquisition Regulations System....110-71 Additional DOC clauses related to service contracting. (a) Insert a clause...

  20. 48 CFR 1337.110-71 - Additional DOC clauses related to service contracting.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Additional DOC clauses related to service contracting. 1337.110-71 Section 1337.110-71 Federal Acquisition Regulations System....110-71 Additional DOC clauses related to service contracting. (a) Insert a clause...

  1. 48 CFR 1337.110-71 - Additional DOC clauses related to service contracting.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Additional DOC clauses related to service contracting. 1337.110-71 Section 1337.110-71 Federal Acquisition Regulations System....110-71 Additional DOC clauses related to service contracting. (a) Insert a clause...

  2. Controversial Biological Issues: An Exploratory Tool for Accessing Teacher Thinking in Relation to Classroom Practice.

    ERIC Educational Resources Information Center

    Van Rooy, Wilhelmina S.

    The research reported here focuses on the beliefs, values and attitudes of one experienced biology teacher (Teacher A) in relation to the teaching of controversial biological issues. Of specific interest is the thinking behind what this teacher conceptualizes are the possibilities and problems for the teaching of controversial issues as part of…

  3. SPECIAL ISSUE OF ATMOSPHERIC ENVIRONMENT FOR PARTICULATE MATTER SUPERSITES PROGRAM AND RELATED STUDIES

    EPA Science Inventory

    This special issue of Atmospheric Environment provides a selection of papers that were presented at the 2005 AAAR PM Supersites Program and Related Studies International Specialty Conference held in Atlanta, GA, 7-11 February 2005. Topics of papers in this issue range from the e...

  4. Beyond the Call of Duty: A Qualitative Study of Teachers' Additional Responsibilities Related to Sexuality Education

    ERIC Educational Resources Information Center

    Eisenberg, Marla E.; Madsen, Nikki; Oliphant, Jennifer A.; Resnick, Michael

    2011-01-01

    Seven focus groups were conducted with sexuality educators in Minnesota to explore ways that teaching sexuality education differs from teaching other health education content and to determine if additional supports or resources are needed for sexuality educators. Teachers described many specific additional responsibilities or concerns related to…

  5. 36 CFR 223.52 - Market-related contract term additions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Market-related contract term... Provisions § 223.52 Market-related contract term additions. (a) Contract provision. (1) Except as provided in... the Forest Service has determined that adverse wood products market conditions have resulted in...

  6. 75 FR 28610 - Draft EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-21

    ...EPA is announcing a 90-day public comment period for the external review draft entitled, ``EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments'' (EPA/600/R- 10/038A). This draft report responds to the key recommendations and comments included in the National Academy of Sciences (NAS) 2006 report. In addition, it includes new analyses on potential human......

  7. A review of return to play issues and sports-related concussion.

    PubMed

    Doolan, Amy W; Day, Daniel D; Maerlender, Arthur C; Goforth, Michael; Gunnar Brolinson, P

    2012-01-01

    Mild traumatic brain injury in sports has become a significant public health concern which has not only received the general public's attention through multiple news media stories involving athletic concussions, but has also resulted in local, state, and national legislative efforts to improve recognition and management. The purpose of this article is to review the current literature for return to play (RTP) guidelines. State, regional, national, and professional legislation on sport-related concussion RTP management issues will be reviewed. This article will be helpful in developing a generalized systematic approach to concussion management and highlight specific RTP guidelines. The article will also touch upon specific contraindications to RTP, the role of neuropsychological testing in RTP, and other considerations and complications that affect an athlete's ability to return to competition. Finally, considerations for terminating an athlete's competitive season or ending a career after sustaining a concussion resulting in prolonged and protracted symptomatology or repeated concussions will be reviewed. PubMed and Google were searched using the key terms mentioned below. In addition, the author's library of concussion-related articles was reviewed for the relevant literature. PMID:21997390

  8. Studying the issues in the additive manufacturing of dental implants by Electron Beam MeltingRTM (EBM)

    NASA Astrophysics Data System (ADS)

    Jamshidinia, Mahdi

    The ability of additive manufacturing (AM) processes to produce complex geometries is resulting in their rapid acceptance by a number of industries. This unique capability could be used for the optimization of the design of functional components that could find an application in different industries such as aerospace, automotive, energy, medical, and implants. However, there are still some challenges confronting this technology such as surface finish, residual stress, dimensional tolerance, processing speed, and anisotropy in microstructure and mechanical properties. Any of the mentioned issues could be influenced by the thermal history of a 3D printed component during the layer-by-layer manufacturing. Therefore, an understanding of the thermal cycling during the AM process is essential. In recent years, significant advances have been achieved in the design, manufacturing, and materials used for dental implants. However, there are still some differences between the natural tooth and a dental implant that might decrease patient satisfaction. One of the differences between the natural tooth and a dental implant is in its modulus of elasticity, which could result in an issue known as bone atrophy. The second important difference between a dental implant and a natural tooth is the fact that a natural tooth is surrounded by a periodontal ligament that allows the tooth to move in three directions. However, the periodontal ligament is destroyed during the extraction of a natural tooth. In the absence of the periodontal ligament, the biting force is directly transferred to the jawbone, resulting in discomfort for the patient. Also, the implant cannot be incorporated with the surrounding natural tooth and form a bridge. In this study, the application of a lattice structure for the manufacturing of a biocompatible dental implant is investigated. Three different lattice structures with different unit cell sizes were experimentally and numerically analyzed. The mechanical

  9. Communication Between Breast Cancer Patients And Their Physicians About Breast-Related Body Image Issues

    PubMed Central

    Cohen, Mallory; Anderson, Rebecca C.; Jensik, Kathleen; Xiang, Qun; Pruszynski, Jessica; Walker, Alonzo P.

    2014-01-01

    Breast cancer patients encounter body image changes throughout their diagnosis, treatment, and recovery from breast cancer. No prospective studies were identified investigating communication between physicians and breast cancer patients related to body image. This qualitative pilot study determines 1) how breast cancer patients prefer their physicians communicate regarding body image changes, and 2) how comfortable physicians are in discussing body image issues with their patients. Data was collected from patients over twelve weeks through the Breast Evaluation Questionnaire (BEQ), a valid and reliable instrument, and a qualitative questionnaire. Ten physicians completed a qualitative questionnaire. The data were analyzed using frequency analysis. Nearly seventy percent of the patients reported there was more the physician could do to improve patient comfort in discussing breast-related body image concerns. Honesty, openness, and directness were important to the patients. Thirty-three percent of the patients answered that their physicians should be honest, open, and direct discussing these issues. On a five point Likert scale (1= very uncomfortable and 5= very comfortable), the physicians most frequently answered a 4 when asked how comfortable they are speaking about breast-related body image issues, however, only four out of ten always address the topic themselves during the patient's visit. This data suggests that patients want honesty, openness, and directness from their physicians related to the discussion of breast-related body image issues. The physicians report they are comfortable speaking about breast-related body image issues; yet, they do not directly initiate the topic. PMID:22929196

  10. Information Retrieval System Design Issues in a Microcomputer-Based Relational DBMS Environment.

    ERIC Educational Resources Information Center

    Wolfram, Dietmar

    1992-01-01

    Outlines the file structure requirements for a microcomputer-based information retrieval system using FoxPro, a relational database management system (DBMS). Issues relating to the design and implementation of such systems are discussed, and two possible designs are examined in terms of space economy and practicality of implementation. (15…

  11. University Intervention into Community Issues as Dialogic Public Relations: A Case Study

    ERIC Educational Resources Information Center

    Byrne, Jamie M.

    2007-01-01

    This paper examines a study of the wastewater collection and treatment issues of Little Rock and North Little Rock, Arkansas by University of Arkansas at Little Rock personnel and how it constitutes dialogic public relations. The paper defines dialogic public relations using Kent and Taylor's work and then uses their criteria to describe how this…

  12. National Technology Standards for K-12 Schools: A Case Study of Unresolved Issues in Public Relations

    ERIC Educational Resources Information Center

    Mullen, Carol A.; Kealy, William A.; Sullivan, Ashley

    2004-01-01

    This article addresses an important need--the dissemination of information relating to technology as a public relations tool--and the associated exigency for administrator and teacher technology training. Specifically, we identify the increased expectations for the performance of school leaders and teachers, as well as unresolved issues in public…

  13. Introduction to the Special Issue: New and Interdisciplinary Approaches to Linguistic Relativity

    ERIC Educational Resources Information Center

    Athanasopoulos, Panos; Bylund, Emanuel; Casasanto, Daniel

    2016-01-01

    This Special Issue of "Language Learning" presents an interdisciplinary state-of-the-art overview of current approaches to linguistic relativity. It contains empirical and theoretical studies and reflections on linguistic relativity from a variety of perspectives, such as associative learning, conceptual transfer, multilingual awareness,…

  14. 76 FR 44507 - Joint Public Roundtable on International Issues Relating to the Implementation of Title VII of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-26

    ... International Issues Relating to the Implementation of Title VII of the Dodd-Frank Wall Street Reform and... issues related to the implementation of Title VII of the Dodd-Frank Wall Street Reform and...

  15. 36 CFR 223.52 - Market-related contract term additions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Market-related contract term additions. 223.52 Section 223.52 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER, SPECIAL FOREST PRODUCTS, AND FOREST...

  16. 36 CFR 223.52 - Market-related contract term additions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false Market-related contract term additions. 223.52 Section 223.52 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER, SPECIAL FOREST PRODUCTS, AND FOREST...

  17. 36 CFR 223.52 - Market-related contract term additions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Market-related contract term additions. 223.52 Section 223.52 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER, SPECIAL FOREST PRODUCTS, AND FOREST...

  18. 36 CFR 223.52 - Market-related contract term additions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Market-related contract term additions. 223.52 Section 223.52 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER, SPECIAL FOREST PRODUCTS, AND FOREST...

  19. Assessment of MRI issues at 3-Tesla for metallic surgical implants: findings applied to 61 additional skin closure staples and vessel ligation clips

    PubMed Central

    2012-01-01

    Purpose Metallic skin closure staples and vessel ligation clips should be tested at 3-Tesla to characterize MRI issues in order to ensure patient safety. Therefore, metallic surgical implants were assessed at 3-Tesla for magnetic field interactions, MRI-related heating, and artifacts. Methods A skin closure staple (Visistat Skin Stapler, staple, Polytetrafluoroethylene, PTFE, coated 316L/316LVM stainless steel; Teleflex Medical, Durham, NC) and a vessel ligation clip (Hemoclip Traditional, stainless steel; Teleflex Medical, Durham, NC) that represented the largest metallic sizes made from materials with the highest magnetic susceptibilities (i.e., based on material information) among 61 other surgical implants (52 metallic implants, 9 nonmetallic implants) underwent evaluation for magnetic field interactions, MRI-related heating, and artifacts using standardized techniques. MRI-related heating was assessed by placing each implant in a gelled-saline-filled phantom with MRI performed using a transmit/receive RF body coil at an MR system reported, whole body averaged SAR of 2.9-W/kg for 15-min. Artifacts were characterized using T1-weighted, SE and GRE pulse sequences. Results Each surgical implant showed minor magnetic field interactions (20- and 27-degrees, which is acceptable from a safety consideration). Heating was not substantial (highest temperature change, ≤ 1.6°C). Artifacts may create issues if the area of interest is in the same area or close to the respective surgical implant. Conclusions The results demonstrated that it would be acceptable for patients with these metallic surgical implants to undergo MRI at 3-Tesla or less. Because of the materials and dimensions of the surgical implants that underwent testing, these findings pertain to 61 additional similar implants. PMID:22230200

  20. Assessment of mindfulness and closely related constructs: Introduction to the special issue.

    PubMed

    Baer, Ruth

    2016-07-01

    This article introduces this special issue on the assessment of mindfulness and other related constructs. The need for refinements in self-report methods and the development of more objective performance-based methods for mindfulness is widely recognized. The six articles in this special issue move the field in these directions. Three of the articles expand the understanding of self-report instruments; the other three describe promising laboratory-based tasks. The articles here show that the assessment of mindfulness and related variables is an active and productive area, with interesting new findings emerging at a high rate. (PsycINFO Database Record PMID:27078184

  1. Containment-emergency-sump performance. Technical findings related to Unresolved Safety Issue A-43. [PWR

    SciTech Connect

    Not Available

    1983-04-01

    This report summarizes key technical findings related to the Unresolved Safety Issue A-43, Containment Emergency Sump Performance, and provides recommendations for resolution of attendant safety issues. The key safety questions relate to: (a) effects of insulation debris on sump performance; (b) sump hydraulic performance as determined by design features, submergence, and plant induced effects, and (c) recirculation pump performance wherein air and/or particulate ingestion can occur. The technical findings presented in this report provide information relevant to the design and performance evaluation of the containment emergency sump.

  2. Love versus abuse: crossgenerational sexual relations of minors: a gay rights issue?

    PubMed

    Graupner, H

    1999-01-01

    The question discussed is how far crossgenerational sexual relations with or by minors could be considered to be a gay rights issue. The author discusses the issue from the perspective of general principles found in the case-law of the European Court on Human Rights. These principles suggest that the basic right to privacy should be interpreted as providing comprehensive protection of the right of children and adolescents to sexual self-determination, namely both the right to effective protection from (unwanted) sex and abuse on the one hand and the right to (wanted) sex on the other. The analysis is based upon the findings of natural and social science as well as an extensive international survey of national legal provisions and it leads to the conclusion that consensual sexual relations of and with adolescents over 14 (out of relations of authority) should be qualified a gay rights issue; likewise (as the exception to the rule) the possibility of filtering out cases from prosecution where a contact/relation is proven (beyond reasonable doubt) as consensual and harmless even though the minor involved is under 14. The legalization of (objectively consensual) sexual relations with persons under 14 as such, however, should not be considered to be a gay rights issue. PMID:10482330

  3. Prospects for cost reductions from relaxing additional cross-border measures related to livestock trade.

    PubMed

    Hop, G E; Mourits, M C M; Slager, R; Oude Lansink, A G J M; Saatkamp, H W

    2013-05-01

    Compared with the domestic trade in livestock, intra-communal trade across the European Union (EU) is subject to costly, additional veterinary measures. Short-distance transportation just across a border requires more measures than long-distance domestic transportation, while the need for such additional cross-border measures can be questioned. This study examined the prospects for cost reductions from relaxing additional cross-border measures related to trade within the cross-border region of the Netherlands (NL) and Germany (GER); that is, North Rhine Westphalia and Lower Saxony. The study constructed a deterministic spread-sheet cost model to calculate the costs of both routine veterinary measures (standard measures that apply to both domestic and cross-border transport) and additional cross-border measures (extra measures that only apply to cross-border transport) as applied in 2010. This model determined costs by stakeholder, region and livestock sector, and studied the prospects for cost reduction by calculating the costs after the relaxation of additional cross-border measures. The selection criteria for relaxing these measures were (1) a low expected added value on preventing contagious livestock diseases, (2) no expected additional veterinary risks in case of relaxation of measures and (3) reasonable cost-saving possibilities. The total cost of routine veterinary measures and additional cross-border measures for the cross-border region was €22.1 million, 58% (€12.7 million) of which came from additional cross-border measures. Two-thirds of this €12.7 million resulted from the trade in slaughter animals. The main cost items were veterinary checks on animals (twice in the case of slaughter animals), export certification and control of export documentation. Four additional cross-border measures met the selection criteria for relaxation. The relaxation of these measures could save €8.2 million (€5.0 million for NL and €3.2 million for GER) annually

  4. Environmental issues related to commercialization of CulnSe{sub 2}- based photovoltaics

    SciTech Connect

    Eberspacher, C.; Fthenakis, V.M.; Moskowitz, P.D.

    1996-07-01

    One of the most promising materials for low-cost thin film photovoltaic cells is copper indium selenide (CuInSe{sub 2} or CIS). As with any new material, successful commercialization of CIS photovoltaic (PV) technology will require attention to environmental issues related to the sources of raw materials, their usage, and the disposal and/or recycling of products at the end of their useful life. This paper focuses on three specific environmental issues related to CIS technology: (i) Economics of the use and re-use of materials; (ii) regulations on environmental disposal and waste handling, and (iii) logistics and economics of recycling and disposing of products by industries faced with comparable environmental issues.

  5. An Additional Motor-Related Field in the Lateral Frontal Cortex of Squirrel Monkeys

    PubMed Central

    Duric, Vanja; Barbay, Scott; Frost, Shawn B.; Stylianou, Antonis; Nudo, Randolph J.

    2008-01-01

    Our earlier efforts to document the cortical connections of the ventral premotor cortex (PMv) revealed dense connections with a field rostral and lateral to PMv, an area we called the frontal rostral field (FR). Here, we present data collected in FR using electrophysiological and anatomical methods. Results show that FR contains an isolated motor representation of the forelimb that can be differentiated from PMv based on current thresholds and latencies to evoke electromyographic activity using intracortical microstimulation techniques. In addition, FR has a different pattern of cortical connections compared with PMv. Together, these data support that FR is an additional, previously undescribed motor-related area in squirrel monkeys. PMID:18424778

  6. Grid related issues for static and dynamic geometry problems using systems of overset structured grids

    NASA Technical Reports Server (NTRS)

    Meakin, Robert L.

    1995-01-01

    Grid related issues of the Chimera overset grid method are discussed in the context of a method of solution and analysis of unsteady three-dimensional viscous flows. The state of maturity of the various pieces of support software required to use the approach is considered. Current limitations of the approach are identified.

  7. African American College Students' Health Behaviors and Perceptions of Related Health Issues.

    ERIC Educational Resources Information Center

    Ford, Denyce S.; Goode, Carolyn R.

    1994-01-01

    A study of African American college students compared students' health-related behaviors with their perceptions of corresponding health issues. Students had low smoking rates but higher alcohol consumption. Most students did not practice good nutrition or daily physical activity. Over half managed stress well, and three-quarters were sexually…

  8. Mediating Effects of Stress, Weight-Related Issues, and Depression on Suicidality in College Students

    ERIC Educational Resources Information Center

    Smith, Sydney S.; Smith Carter, Jocelyn; Karczewski, Sabrina; Pivarunas, Bernadette; Suffoletto, Shannon; Munin, Art

    2015-01-01

    Objective: Through a holistic health lens, the current study examines the effects of weight-related issues and stress on suicidality while controlling for depressive symptoms in college students. Participants: In total, 872 undergraduate and graduate students at DePaul University completed the American College Health Association-National College…

  9. Questions and Answers Related to Policy Issues about Students with Disabilities.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Public Instruction, Raleigh. Exceptional Children Div.

    This document is designed to provide information to North Carolina administrators and teachers on policy issues related to students with disabilities. Policy letters from the U.S. Office of Special Education Programs and the Office of Civil Rights, as well as "Analysis of Comments and Changes" and "Notice of Interpretations on IEPs" of the Federal…

  10. TPV energy conversion: A review of material and cell related issues

    SciTech Connect

    Bhat, I.B.; Borrego, J.M.; Gutmann, R.J.; Ostrogorsky, A.G.

    1996-08-01

    This paper presents an overview of thermophotovoltaic (TPV) energy conversion using low band gap semiconductor photovoltaic cells. Physics of PN junctions related to TPV cells is described and the factors that affect overall cell efficiencies are outlined. Current status of bulk and epitaxial growth of TPV materials and cell fabrication issues are also described.

  11. A Study of Current Trends and Issues Related to Technical/Engineering Design Graphics.

    ERIC Educational Resources Information Center

    Clark, Aaron C.; Scales Alice

    2000-01-01

    Presents results from a survey of engineering design graphics educators who responded to questions related to current trends and issues in the profession of graphics education. Concludes that there is a clear trend in institutions towards the teaching of constraint-based modeling and computer-aided manufacturing. (Author/YDS)

  12. Allostatic Load: Single Parents, Stress-Related Health Issues, and Social Care

    ERIC Educational Resources Information Center

    Johner, Randy L.

    2007-01-01

    This article explores the possible relationships between allostatic load (AL) and stress-related health issues in the low-income single-parent population, using both a population health perspective (PHP) and a biological framework. A PHP identifies associations among such factors as gender, income, employment, and social support and their…

  13. Teacher to Teacher: What Texts Effectively Raise Issues Related to 9/11 for Secondary Students?

    ERIC Educational Resources Information Center

    English Journal, 2006

    2006-01-01

    This article deals with texts that effectively raise issues related to 9/11 for secondary students, as discussed by several teachers. Kevin J. Collins from St. Thomas Aquinas High School says, "Elephant," Gus Van Sant's exploration of a Columbine-like tragedy, underscores the current generation's attempt to define the meaning of events in…

  14. WORKSHOP ON GAM-RELATED STATISTICAL ISSUES IN PARTICULATE MATTER EPIDEMIOLOGY

    EPA Science Inventory

    The U.S. Environmental Protection Agency's (EPA) National Center for Environmental Assessment (NCEA), within the Agency's Office of Research and Development, is announcing a Workshop on GAM-Related Statistical Issues in Particulate Matter (PM)Epidemiology. The workshop is open to...

  15. Technical Note: Some Issues Related to the Selection of Polymers for Aerospace Oxygen Systems

    NASA Technical Reports Server (NTRS)

    Hirsch, David; Beeson, Harold

    2004-01-01

    Materials intended for use in aerospace oxygen systems are commonly screened for oxygen compatibility following NASA STD 6001. This standard allows qualification of materials based on results provided by only one test method. Potential issues related to this practice are reviewed and recommendations are proposed that would lead to improved aerospace oxygen systems safety.

  16. Prospective Teachers' Perceptions about the Concept of Sustainable Development and Related Issues in Oman

    ERIC Educational Resources Information Center

    Ambusaidi, Abdullah; Al Washahi, Maryam

    2016-01-01

    This study aims to investigate, from the Omani's prospective, teachers' perceptions about the concept of sustainable development (SD) and three related issues (cultural diversity, renewable energy and equity). The sample consisted of 159 prospective teachers from Sultan Qaboos University. Data were collected via a questionnaire comprising a list…

  17. Science-Related Social Issues: Challenges for the Social Studies. ERIC Digest No. 16.

    ERIC Educational Resources Information Center

    Patrick, John J.; Remy, Richard C.

    Background, rationale, and promising practices for teaching about science-related social issues in the science and social studies classroom are presented. Material is divided into five sections, each introduced with a topical question. The first section considers the challenges associated with the pervasive influences of science and technology in…

  18. 78 FR 9020 - Wireline Competition Bureau Seeks Further Comment on Specific Issues Related to the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-07

    ..., 76 FR 73830, November 29, 2011 and 76 FR 78384, December 16, 2011, which comprehensively reformed and... accompanying FNPRM, 76 FR 78384, December 16, 2011, the Commission sought comment on various issues relating to... Areas Fund, what downward adjustments would represent an appropriate balancing of the ``economic...

  19. Dollars and Directives: Issues and Problems Related to Financial Support and Legal Authorizations of Community Colleges.

    ERIC Educational Resources Information Center

    Martorana, S. V.; And Others

    This monograph is concerned with the issues and problems raised by recent trends in state legislative activity related to community and junior colleges and in patterns of funding these institutions. The first of two parts discusses legislation directly or indirectly affecting policies for financing postsecondary education in general and community…

  20. How Do Learners in Developed and Developing Countries Relate to Environmental Issues?

    ERIC Educational Resources Information Center

    Trumper, Ricardo

    2010-01-01

    The present study was carried out in the framework of earlier research on environmental education for sustainability, using data collected in the ROSE Project. Attention was focused mainly on students' responses to sections and items related to environmental issues, regarding their countries' degree of development. The research questions dealt…

  1. Students' Understandings of Religious Identities and Relations: Issues of Social Cohesion and Citizenship

    ERIC Educational Resources Information Center

    Keddie, Amanda

    2014-01-01

    The focus in this article is on issues of social cohesion and citizenship as they relate to students' understandings of religion and religious identity. The article draws on data gathered from a study conducted at a highly diverse English comprehensive school and is set amid broader anxieties about religion, community disharmony and national…

  2. Japanese and American Preservice Teachers' Attitudes Toward Global Issues and Relations.

    ERIC Educational Resources Information Center

    Parker, Walter; Glenn, Allen; Mizoue, Yasushi; Meriwether, Crystal; Gardner, William

    1997-01-01

    Compared Japanese and U.S. preservice teachers' attitudes about global issues and global relations, surveying preservice elementary teachers at one Japanese and two American universities. Results indicated that the groups were moderately worldminded overall, and they differed significantly in their levels of worldmindedness. Four out of ten survey…

  3. Organizational Issues Related to Governance and Management of Off-Campus Centers

    ERIC Educational Resources Information Center

    Macklin, Cedric Dewayne

    2012-01-01

    Extensive research has been conducted on students pursuing degrees off-campus; however, limited studies have been directed to explain the growing practice of students enrolling in courses and degrees at off-campus degree centers. The purpose of this dissertation was to explore the organizational issues related to governance and management of…

  4. Issues related to handling Exploration Seismic data within the EU FP7 GeoSeas project

    NASA Astrophysics Data System (ADS)

    Diviacco, Paolo; Cox, Simon

    2010-05-01

    additional indexing information is encoded in what is effectively an extension to CDI, but using cross-domain standards, which will allow geophysics data to be discovered and assessed in a common framework with other marine and oceanography data. Data access in this field poses further problems. There are significant economic interests in seismic data. The publication of relatively raw data through web service interfaces must follow a schedule that respect legitimate intellectual property concerns. Nevertheless, more open data publication can be used to position the data owner within the scientific community and to attract new projects and therefore funding. From the data owner point of view the difficulty in balancing opening and protection can be overcome only offering to external users a controlled, server-side, web-based data access. This is also preferred considering that data volumes are large (Seismic data (post-stack) is often 50-100 MB, while field data can easily reach GB).

  5. 42 CFR 493.645 - Additional fee(s) applicable to approved State laboratory programs and laboratories issued a...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS General Administration § 493.645 Additional fee(s) applicable to approved State laboratory programs...

  6. 42 CFR 493.645 - Additional fee(s) applicable to approved State laboratory programs and laboratories issued a...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS General Administration § 493.645 Additional fee(s) applicable to approved State laboratory programs...

  7. Mining Health-Related Issues in Consumer Product Reviews by Using Scalable Text Analytics

    PubMed Central

    Torii, Manabu; Tilak, Sameer S.; Doan, Son; Zisook, Daniel S.; Fan, Jung-wei

    2016-01-01

    In an era when most of our life activities are digitized and recorded, opportunities abound to gain insights about population health. Online product reviews present a unique data source that is currently underexplored. Health-related information, although scarce, can be systematically mined in online product reviews. Leveraging natural language processing and machine learning tools, we were able to mine 1.3 million grocery product reviews for health-related information. The objectives of the study were as follows: (1) conduct quantitative and qualitative analysis on the types of health issues found in consumer product reviews; (2) develop a machine learning classifier to detect reviews that contain health-related issues; and (3) gain insights about the task characteristics and challenges for text analytics to guide future research. PMID:27375358

  8. Mining Health-Related Issues in Consumer Product Reviews by Using Scalable Text Analytics.

    PubMed

    Torii, Manabu; Tilak, Sameer S; Doan, Son; Zisook, Daniel S; Fan, Jung-Wei

    2016-01-01

    In an era when most of our life activities are digitized and recorded, opportunities abound to gain insights about population health. Online product reviews present a unique data source that is currently underexplored. Health-related information, although scarce, can be systematically mined in online product reviews. Leveraging natural language processing and machine learning tools, we were able to mine 1.3 million grocery product reviews for health-related information. The objectives of the study were as follows: (1) conduct quantitative and qualitative analysis on the types of health issues found in consumer product reviews; (2) develop a machine learning classifier to detect reviews that contain health-related issues; and (3) gain insights about the task characteristics and challenges for text analytics to guide future research. PMID:27375358

  9. Bio-ethical and legal issues in relation to HIV/AIDS: the Uganda experience.

    PubMed

    Yusuf, N K

    1998-01-01

    In Uganda, as in many other countries, there is a vacuum regarding an appropriate legal and ethical response to the HIV/AIDS pandemic. Whereas much has been done to address the HIV/AIDS pandemic in a multidisciplinary way, very little has been done regarding legal and ethical issues. Hence, cases of claimants to have cures for AIDS, spiritual healers and sale of fake drugs plus unauthorized vaccine and drug trials are on the increase. The rights and needs of people infected with HIV/AIDS are not adequately addressed. The property rights of those affected by the pandemic continue to be abused. Therefore there is need to mobilize doctors, lawyers and human rights activists who should advocate and address these issues. This paper therefore highlights the critical bio-ethical and legal issues in relation to HIV/AIDS. PMID:10396922

  10. On the issues related to compliance assessment of ICNIRP 2010 basic restrictions.

    PubMed

    De Santis, Valerio; Chen, Xi Lin

    2014-06-01

    This article discusses technical issues related to compliance assessment of ICNIRP 2010 basic restrictions. Several difficulties are identified in this study when assessing the spatial average and 99th percentile value of the electric field. These issues are mainly attributed to the lack of clarity in the guideline specifications, which leads to inadequate or irreproducible results. Effects on compliance results due to such ambiguous procedures are hereby investigated, with particular focus on technical issues rather than biological ones. Examples spanning from simple canonical test cases to realistic applications have been selected to highlight the strong variability in dosimetry results. Based on our findings, revisiting the ICNIRP 2010 guidelines is strongly recommended, and proposed alternative solutions are outlined. PMID:24705441

  11. 41 CFR 102-83.30 - In addition to its mission and program requirements, are there any other issues that Federal...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false In addition to its mission and program requirements, are there any other issues that Federal agencies must consider in identifying the delineated area? 102-83.30 Section 102-83.30 Public Contracts and Property Management Federal Property Management Regulations System...

  12. Leveraging People-Related Maturity Issues for Achieving Higher Maturity and Capability Levels

    NASA Astrophysics Data System (ADS)

    Buglione, Luigi

    During the past 20 years Maturity Models (MM) become a buzzword in the ICT world. Since the initial Crosby's idea in 1979, plenty of models have been created in the Software & Systems Engineering domains, addressing various perspectives. By analyzing the content of the Process Reference Models (PRM) in many of them, it can be noticed that people-related issues have little weight in the appraisals of the capabilities of organizations while in practice they are considered as significant contributors in traditional process and organizational performance appraisals, as stressed instead in well-known Performance Management models such as MBQA, EFQM and BSC. This paper proposes some ways for leveraging people-related maturity issues merging HR practices from several types of maturity models into the organizational Business Process Model (BPM) in order to achieve higher organizational maturity and capability levels.

  13. Policy issues related to educating the future Israeli medical workforce: an international perspective.

    PubMed

    Schoenbaum, Stephen C; Crome, Peter; Curry, Raymond H; Gershon, Elliot S; Glick, Shimon M; Katz, David R; Paltiel, Ora; Shapiro, Jo

    2015-01-01

    A 2014 external review of medical schools in Israel identified several issues of importance to the nation's health. This paper focuses on three inter-related policy-relevant topics: planning the physician and healthcare workforce to meet the needs of Israel's population in the 21(st) century; enhancing the coordination and efficiency of medical education across the continuum of education and training; and the financing of medical education. All three involve both education and health care delivery. The physician workforce is aging and will need to be replenished. Several physician specialties have been in short supply, and some are being addressed through incentive programs. Israel's needs for primary care clinicians are increasing due to growth and aging of the population and to the increasing prevalence of chronic conditions at all ages. Attention to the structure and content of both undergraduate and graduate medical education and to aligning incentives will be required to address current and projected workforce shortage areas. Effective workforce planning depends upon data that can inform the development of appropriate policies and on recognition of the time lag between developing such policies and seeing the results of their implementation. The preclinical and clinical phases of Israeli undergraduate medical education (medical school), the mandatory rotating internship (stáge), and graduate medical education (residency) are conducted as separate "silos" and not well coordinated. The content of basic science education should be relevant to clinical medicine and research. It should stimulate inquiry, scholarship, and lifelong learning. Clinical exposures should begin early and be as hands-on as possible. Medical students and residents should acquire specific competencies. With an increasing shift of medical care from hospitals to ambulatory settings, development of ambulatory teachers and learning environments is increasingly important. Objectives such as these

  14. Smog chamber experiments to test oxidant related control strategy issues. Final report 1978-81

    SciTech Connect

    Kamens, R.M.; Jeffries, H.E.; Sexton, K.G.; Gerhardt, A.A.

    1982-03-01

    Outdoor smog chamber experiments were performed to address various issues relating to ozone (O3) production and oxidant control strategies. Temperature effects on single hydrocarbon-NOx systems were studied. Propylene-NOx systems were modeled with particular attention to peroxynitric acid chemistry. Mechanisms were developed to model the O3 reactions with the two major isoprene daughter products, methylvinylketone and methacrolein. Chamber systems with isoprene and O3 were also modeled.

  15. Revisiting the Dialogue on the Transition from Coteaching to Inservice Teaching: New Frameworks, Additional Benefits and Emergent Issues

    ERIC Educational Resources Information Center

    Wassell, Beth; LaVan, Sarah Kate

    2009-01-01

    In this rejoinder, we respond to the major points made by Gallo-Fox (this forum), Beers (this forum), Carambo and Stickney (this forum), and Murphy, Carlisle and Beggs (this forum). We focus primarily on the benefits and considerations that stem from employing additional theoretical frameworks for analyzing research in coteaching. We also address…

  16. On the Conceptual Issues Surrounding the Notion of Relational Bohmian Dynamics

    NASA Astrophysics Data System (ADS)

    Vassallo, Antonio; Ip, Pui Him

    2016-02-01

    The paper presents a program to construct a non-relativistic relational Bohmian theory, that is, a theory of N moving point-like particles that dispenses with space and time as fundamental background structures. The relational program proposed is based on the best-matching framework originally developed by Julian Barbour. In particular, the paper focuses on the conceptual problems that arise when trying to implement such a program. It is argued that pursuing a relational strategy in the Bohmian context leads to a more parsimonious ontology than that of standard Bohmian mechanics without betraying the original motivations for adopting a primitive ontology approach to quantum physics. It is also shown how a relational Bohmian approach might clarify the issue of the timelessness of the dynamics resulting from the quantization of a classical relational system of particles.

  17. On the Conceptual Issues Surrounding the Notion of Relational Bohmian Dynamics

    NASA Astrophysics Data System (ADS)

    Vassallo, Antonio; Ip, Pui Him

    2016-08-01

    The paper presents a program to construct a non-relativistic relational Bohmian theory, that is, a theory of N moving point-like particles that dispenses with space and time as fundamental background structures. The relational program proposed is based on the best-matching framework originally developed by Julian Barbour. In particular, the paper focuses on the conceptual problems that arise when trying to implement such a program. It is argued that pursuing a relational strategy in the Bohmian context leads to a more parsimonious ontology than that of standard Bohmian mechanics without betraying the original motivations for adopting a primitive ontology approach to quantum physics. It is also shown how a relational Bohmian approach might clarify the issue of the timelessness of the dynamics resulting from the quantization of a classical relational system of particles.

  18. Revisiting the dialogue on the transition from coteaching to inservice teaching: new frameworks, additional benefits and emergent issues

    NASA Astrophysics Data System (ADS)

    Wassell, Beth; Lavan, Sarah Kate

    2009-06-01

    In this rejoinder, we respond to the major points made by Gallo-Fox (this forum), Beers (this forum), Carambo and Stickney (this forum), and Murphy, Carlisle and Beggs (this forum). We focus primarily on the benefits and considerations that stem from employing additional theoretical frameworks for analyzing research in coteaching. We also address some of the future directions that should be explored in coteaching research.

  19. 26 CFR 1.163-12 - Deduction of original issue discount on instrument held by related foreign person.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Deduction of original issue discount on... Deductions for Individuals and Corporations § 1.163-12 Deduction of original issue discount on instrument... with respect to the deduction of original issue discount owed to a related foreign person. A...

  20. 78 FR 57587 - Environmental Impact and Related Procedures-Programmatic Agreements and Additional Categorical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-19

    ... (23 CFR 771.117(b); 23 CFR 771.118(b)). The Agencies first issued their NEPA Procedures in 1980 (45 FR... issued the 1987 revisions (52 FR 3264, Aug. 28, 1987) as part of a departmentwide effort to streamline... previously listed by an agency could be considered for CE status on a case-by-case basis'' (52 FR 32651,...

  1. Overview of regulatory/policy/economic issues related to carbon dioxide.

    PubMed

    Leaf, Dennis; Verolme, Hans J H; Hunt, William F

    2003-06-01

    This is an overview of Session 2c dealing with the regulatory, policy and economic issues related to carbon dioxide and its impact on global climate change. The information is taken from the two papers presented in this session (the U.S. Perspective by Dennis Leaf and the European Perspective by Hans J.H. Verolme) and from the panel discussion that took place at the end of the session. The overview focuses primarily on the policy responses of both the United States (US) and the United Kingdom (UK) to changes in global atmospheric pollution. To a lesser extent, the progress of policy responses to these changes is discussed. The United Nations Framework Convention on Climate Change (UNFCCC) has been signed and ratified by over 180 countries. The UNFCCC contained no binding targets or timetables for emissions reductions. The Kyoto Protocol [United Nations. Kyoto Protocol to the United Nations Framework Convention on Climate Change. UNEP.IUC/99/10. Chatlelaine, Switzerland: United Nations Environment Programme's Information Unit for Conventions, for the Climate Change Secretariat, 1997] to the UNFCCC did contain targets and timetables for reductions of greenhouse gases on the part of developed countries. The US has signed but not ratified the Kyoto Protocol. The US has experienced some movement to reduce greenhouse gas emissions on the part of various levels of government, as well as the private sector. The UK's commitment to reducing green house gases is laid down in the UK Climate Change Programme 2000. The UK is a member of the European Union (EU). In this context, an example of EU-wide progress, the voluntary agreement with car manufacturers to reduce CO(2) emissions in new vehicles, will be discussed. In addition, there will be some discussion on the UK CO(2) trading scheme that created the first market in the world in April 2001. Overall, the policy process is constantly informed by scientific research. In the case of climate change, much of this work is carried

  2. Current research issues related to post-wildfire runoff and erosion processes

    USGS Publications Warehouse

    Moody, John A.; Shakesby, Richard A.; Robichaud, Peter R.; Cannon, Susan H.; Martin, Deborah A.

    2013-01-01

    Research into post-wildfire effects began in the United States more than 70 years ago and only later extended to other parts of the world. Post-wildfire responses are typically transient, episodic, variable in space and time, dependent on thresholds, and involve multiple processes measured by different methods. These characteristics tend to hinder research progress, but the large empirical knowledge base amassed in different regions of the world suggests that it should now be possible to synthesize the data and make a substantial improvement in the understanding of post-wildfire runoff and erosion response. Thus, it is important to identify and prioritize the research issues related to post-wildfire runoff and erosion. Priority research issues are the need to: (1) organize and synthesize similarities and differences in post-wildfire responses between different fire-prone regions of the world in order to determine common patterns and generalities that can explain cause and effect relations; (2) identify and quantify functional relations between metrics of fire effects and soil hydraulic properties that will better represent the dynamic and transient conditions after a wildfire; (3) determine the interaction between burned landscapes and temporally and spatially variable meso-scale precipitation, which is often the primary driver of post-wildfire runoff and erosion responses; (4) determine functional relations between precipitation, basin morphology, runoff connectivity, contributing area, surface roughness, depression storage, and soil characteristics required to predict the timing, magnitudes, and duration of floods and debris flows from ungaged burned basins; and (5) develop standard measurement methods that will ensure the collection of uniform and comparable runoff and erosion data. Resolution of these issues will help to improve conceptual and computer models of post-wildfire runoff and erosion processes.

  3. Google and Women’s Health-Related Issues: What Does the Search Engine Data Reveal?

    PubMed Central

    Baazeem, Mazin

    2014-01-01

    Objectives Identifying the gaps in public knowledge of women’s health related issues has always been difficult. With the increasing number of Internet users in the United States, we sought to use the Internet as a tool to help us identify such gaps and to estimate women’s most prevalent health concerns by examining commonly searched health-related keywords in Google search engine. Methods We collected a large pool of possible search keywords from two independent practicing obstetrician/gynecologists and classified them into five main categories (obstetrics, gynecology, infertility, urogynecology/menopause and oncology), and measured the monthly average search volume within the United States for each keyword with all its possible combinations using Google AdWords tool. Results We found that pregnancy related keywords were less frequently searched in general compared to other categories with an average of 145,400 hits per month for the top twenty keywords. Among the most common pregnancy-related keywords was “pregnancy and sex’ while pregnancy-related diseases were uncommonly searched. HPV alone was searched 305,400 times per month. Of the cancers affecting women, breast cancer was the most commonly searched with an average of 247,190 times per month, followed by cervical cancer then ovarian cancer. Conclusion The commonly searched keywords are often issues that are not discussed in our daily practice as well as in public health messages. The search volume is relatively related to disease prevalence with the exception of ovarian cancer which could signify a public fear. PMID:25422723

  4. Age and work environment characteristics in relation to sleep: Additive, interactive and curvilinear effects.

    PubMed

    Parkes, Katharine R

    2016-05-01

    Although additive combinations of age and work environment characteristics have been found to predict sleep impairment, possible age x work environment interactions have been largely disregarded. The present study examined linear and curvilinear interactions of age with work environment measures in relation to sleep quality and duration. Survey data were collected from offshore day-shift personnel (N = 901). Main effects and interactions of the age terms with work environment measures (job demand, control, and social support, physical environment and strenuous work) were evaluated. Sleep duration was predicted by a curvilinear interaction, age(2)x job demand (p < .005), and by the age x social support interaction (p < .002); sleep quality was predicted by age x job demand (p < .002). Job control and physical environment showed significant additive effects. At a time when older employees are encouraged to remain in the workforce, the findings serve to increase understanding of how ageing and work demands jointly contribute to sleep impairment. PMID:26851463

  5. Influence of oxygen partial pressure and silver additions on microstructure and related properties of YBCO superconductors

    SciTech Connect

    Singh, J.P.; Joo, J.; Guttschow, R.; Poeppel, R.B.

    1992-02-01

    Microstructure has a great influence on the mechanical and superconducting properties of YBCO. Mechanical properties of YBCO can be improved by both modifying the monolithic microstructure and developing composites of YBCO with silver (Ag). When monolithic YBCO was sintered to high densities ({approx} 91%) at a relatively low temperature ({approx} 910{degrees}C) by controlling oxygen partial pressure during sintering, the result was a small-grain microstructure (average grain size {approx} 5 {mu}m) and hence a high strength of 191 {plus minus} 7 MPa. Addition of Ag as a second phase further improved the strength of YBCO. Composites of YBCO with 10 to 15 vol % Ag has a strength of 225 {plus minus} 6 MPa and a fracture toughness of 3.3 {plus minus} 0.2 MPa{radical}m. These improvements are believed to be due to compressive stresses in the YBCO matrix as a result of thermal mismatch between the YBCO and Ag phases. Furthermore, the Ag particles may provide increased resistance to crack propagation by pinning the crack. On the other hand, addition of Ag as a dopant to substitute for Cu sites in YBCO has a profound but nonmonotonic effect on grain microstructure and the resulting critical current density.

  6. Influence of oxygen partial pressure and silver additions on microstructure and related properties of YBCO superconductors

    SciTech Connect

    Singh, J.P.; Joo, J.; Guttschow, R.; Poeppel, R.B.

    1992-02-01

    Microstructure has a great influence on the mechanical and superconducting properties of YBCO. Mechanical properties of YBCO can be improved by both modifying the monolithic microstructure and developing composites of YBCO with silver (Ag). When monolithic YBCO was sintered to high densities ({approx} 91%) at a relatively low temperature ({approx} 910{degrees}C) by controlling oxygen partial pressure during sintering, the result was a small-grain microstructure (average grain size {approx} 5 {mu}m) and hence a high strength of 191 {plus_minus} 7 MPa. Addition of Ag as a second phase further improved the strength of YBCO. Composites of YBCO with 10 to 15 vol % Ag has a strength of 225 {plus_minus} 6 MPa and a fracture toughness of 3.3 {plus_minus} 0.2 MPa{radical}m. These improvements are believed to be due to compressive stresses in the YBCO matrix as a result of thermal mismatch between the YBCO and Ag phases. Furthermore, the Ag particles may provide increased resistance to crack propagation by pinning the crack. On the other hand, addition of Ag as a dopant to substitute for Cu sites in YBCO has a profound but nonmonotonic effect on grain microstructure and the resulting critical current density.

  7. Enhancement of aluminum tolerance in wheat by addition of chromosomes from the wild relative Leymus racemosus

    PubMed Central

    Mohammed, Yasir Serag Alnor; Eltayeb, Amin Elsadig; Tsujimoto, Hisashi

    2013-01-01

    Aluminum (Al) toxicity is the key factor limiting wheat production in acid soils. Soil liming has been used widely to increase the soil pH, but due to its high cost, breeding tolerant cultivars is more cost-effective mean to mitigate the problem. Tolerant cultivars could be developed by traditional breeding, genetic transformation or introgression of genes from wild relatives. We used 30 wheat alien chromosome addition lines to identify new genetic resources to improve wheat tolerance to Al and to identify the chromosomes harboring the tolerance genes. We evaluated these lines and their wheat background Chinese Spring for Al tolerance in hydroponic culture at various Al concentrations. We also investigated Al uptake, oxidative stress and cell membrane integrity. The L. racemosus chromosomes A and E significantly enhanced the Al tolerance of the wheat in term of relative root growth. At the highest Al concentration tested (200 μM), line E had the greatest tolerance. The introgressed chromosomes did not affect Al uptake of the tolerant lines. We attribute the improved tolerance conferred by chromosome E to improved cell membrane integrity. Chromosome engineering with these two lines could produce Al-tolerant wheat cultivars. PMID:24399913

  8. Enhancement of aluminum tolerance in wheat by addition of chromosomes from the wild relative Leymus racemosus.

    PubMed

    Mohammed, Yasir Serag Alnor; Eltayeb, Amin Elsadig; Tsujimoto, Hisashi

    2013-12-01

    Aluminum (Al) toxicity is the key factor limiting wheat production in acid soils. Soil liming has been used widely to increase the soil pH, but due to its high cost, breeding tolerant cultivars is more cost-effective mean to mitigate the problem. Tolerant cultivars could be developed by traditional breeding, genetic transformation or introgression of genes from wild relatives. We used 30 wheat alien chromosome addition lines to identify new genetic resources to improve wheat tolerance to Al and to identify the chromosomes harboring the tolerance genes. We evaluated these lines and their wheat background Chinese Spring for Al tolerance in hydroponic culture at various Al concentrations. We also investigated Al uptake, oxidative stress and cell membrane integrity. The L. racemosus chromosomes A and E significantly enhanced the Al tolerance of the wheat in term of relative root growth. At the highest Al concentration tested (200 μM), line E had the greatest tolerance. The introgressed chromosomes did not affect Al uptake of the tolerant lines. We attribute the improved tolerance conferred by chromosome E to improved cell membrane integrity. Chromosome engineering with these two lines could produce Al-tolerant wheat cultivars. PMID:24399913

  9. Work-related stress and bullying: gender differences and forensic medicine issues in the diagnostic procedure

    PubMed Central

    2011-01-01

    Background The attention of international agencies and scientific community on bullying and work-related stress is increasing. This study describes the gender differences found in victims of bullying and work-related stress in an Italian case series and analyzes the critical issues in the diagnostic workup. Methods Between 2001 and 2009 we examined 345 outpatients (148 males, 197 females; mean age: 41 ± 10.49) for suspected psychopathological work-related problems. Diagnosis of bullying was established using international criteria (ICD-10 and DSM-IV). Results After interdisciplinary diagnostic evaluation (Occupational Medicine Unit, Psychology and Psychiatry Service), the diagnosis of bullying was formulated in 35 subjects, 12 males and 23 females (2 cases of Post-Traumatic Stress Disorder and 33 of Adjustment Disorder). Fifty-four (20 males, 34 females) suffered from work-related anxiety, while work-unrelated Adjustment Disorder and other psychiatric disorders were diagnosed in 7 and 112 subjects, respectively. Women between 34 and 45 years showed a high prevalence (65%) of "mobbing syndrome" or other work-related stress disorders. Conclusions At work, women are more subject to harassment (for personal aspects related to emotional and relational factors) than men. The knowledge of the phenomenon is an essential requisite to contrast bullying; prevention can be carried out only through effective information and training of workers and employers, who have the legal obligation to preserve the integrity of the mental and physical status of their employees during work. PMID:22088163

  10. Environmental, health and safety issues related to commercializing CuInSe{sub 2}-based photovoltaics

    SciTech Connect

    Eberspacher, C.; Fthenakis, V.M.; Moskowtiz, P.D.

    1996-07-01

    Photovoltaics technology is rapidly evolving towards a new generation of low-cost thin film technologies. One of the most promising materials in this new generation is copper indium selenide (CuInSe{sub 2} or CIS). As with any new material, successful commercialization of CIS photovoltaic (PV) technology will require attention to environmental, health and safety issues, including consideration of the sources, usage, and end-of-product-life disposal and/or recycling of the constituent materials. This work focuses on three specific environmental, health and safety (EH and S) issues related to CIS PV: (1) economics are analyzed to determine their impact on materials use and re-use; (2) Federal and California State environmental disposal and waste handling regulations are analyzed to evaluate their impact on PV module manufacturing and end-of-life module handling; and (3) the logistics and economics of product recycling and waste disposal by industries with comparable EH and S issues are examined to quantify the corresponding options available for handling, disposing of and/or recycling manufacturing by-products and end-of-life modules.

  11. Economic and demographic issues related to deployment of the Satellite Power System (SPS)

    NASA Technical Reports Server (NTRS)

    Baldwin, T. E.; Hill, L. G.; Santini, D. J.; Stenehjem, E. J.

    1978-01-01

    Growth in energy consumption stimulated interest in exploitation of renewable sources of electric energy. One technology that was proposed is the Satellite Power System (SPS). Before committing the U.S. to such a large program, the Department of Energy and the National Aeronautics and Space Administration are jointly participating in an SPS Concept Development and Evaluation Program. This white paper on industrial and population relocation is part of the FY 78 preliminary evaluation of related socio-economic issues. Results of four preliminary assessment activities are documented.

  12. 25 CFR 37.111 - What role does a tribe have in issues relating to school boundaries?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What role does a tribe have in issues relating to school boundaries? 37.111 Section 37.111 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION GEOGRAPHIC BOUNDARIES All Schools § 37.111 What role does a tribe have in issues relating to...

  13. 25 CFR 37.111 - What role does a tribe have in issues relating to school boundaries?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What role does a tribe have in issues relating to school boundaries? 37.111 Section 37.111 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION GEOGRAPHIC BOUNDARIES All Schools § 37.111 What role does a tribe have in issues relating to...

  14. 25 CFR 37.111 - What role does a tribe have in issues relating to school boundaries?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What role does a tribe have in issues relating to school boundaries? 37.111 Section 37.111 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION GEOGRAPHIC BOUNDARIES All Schools § 37.111 What role does a tribe have in issues relating to...

  15. Risk assessment related to veterinary biologicals: specific issues in developing nations.

    PubMed

    Ward, D E

    1995-12-01

    The author reviews both technical and socio-economic issues in developing nations, in relation to veterinary biologicals. Health risk assessment is a specific process to estimate the likelihood that animals, humans or ecological systems will be affected adversely by a chemical or physical agent, or biological product, under a specific set of conditions. Some technical issues (quality assurance, good manufacturing practice, education of end-users, field monitoring) apply equally well in developed, industrialised and in developing, pre-industrialised nations. Many regions have documented unique diseases (trypanosomosis, tick diseases, theileriosis) or high disease prevalence which may influence risk assessment results. This emphasises the need for scientifically-valid risk assessment methodologies in developing nations. Developing nations also have various socio-economic concerns, which may not be based on scientific fact but, nonetheless, affect trade in, and use of, veterinary biologicals. These non-scientific but perceived problems and issues are briefly discussed, and possible solutions are presented. The way in which countries deal with such perceived problems and issues in a context of internationally harmonised norms for risk assessment impinges on livestock farmers in developing nations. Finally, the author presents possible ways to correct the potentially widening cost gap between conventional, proven veterinary biologicals and newly-developed products. The results of risk assessment of veterinary biologicals influence risk management in both developed and less-developed nations. It is important to agree upon scientifically-based risk management guidelines which may be applied in all countries. The effect of the agreements of the Uruguay Round of the General Agreement on Tariffs and Trade on trade in veterinary biologicals in developing nations is reviewed. PMID:8639967

  16. African American college students' health behaviors and perceptions of related health issues.

    PubMed

    Ford, D S; Goode, C R

    1994-03-01

    The authors identify specific health-related behaviors of African American college students and compare them with the students' perceptions of corresponding health issues. Among students surveyed, the rate of cigarette smoking (4%) was very low compared with smoking rates found in a national survey (14%); but alcohol consumption was relatively high (63%), although lower than the national average of 91%. More men than women smoked, but more women than men reported they drank alcoholic beverages. Most students (90.2%) said they did not usually eat breakfast, 73.6% reported that their diets were not nutritionally balanced, and the majority (55.4%) were not involved in daily physical activity. More than half (63%) of the students reported satisfactorily handling stress, and 74.1% indicated that they were sexually active. Respondents perceived the most important health issues facing college students as HIV/AIDS and sexually transmitted diseases (STDs), birth control, date rape, stress management, suicide, and alcohol and other drugs. PMID:8201133

  17. Emerging issues on comprehensive hemophilia care: preventing, identifying, and monitoring age-related comorbidities.

    PubMed

    Coppola, Antonio; Santoro, Cristina; Franchini, Massimo; Mannucci, Caterina; Mogavero, Selene; Molinari, Angelo Claudio; Schinco, Piercarla; Tagliaferri, Annarita; Santoro, Rita Carlotta

    2013-10-01

    Life expectancy for persons with hemophilia (PWH) has considerably increased in the last decades as a direct result of the availability of modern therapies to control the clotting defect. Because their life expectancy now matches that of the general population, PWH are experiencing age-related comorbidities, such as, cardiovascular diseases, metabolic syndrome, renal diseases, sexuality issues, malignancies, and neurologic problems, that until recently have been rarely seen in this group of patients. In this article, we present a summary of the current knowledge on the aging PWH along with the clinical approaches that may be integrated into the routine comprehensive care of these patients for preventing, diagnosing, and monitoring age-related comorbidities. In general, patients with and without hemophilia should receive similar care, with close collaboration between the physician treating PWH and the specialty expert treating the comorbid disease. PMID:24014070

  18. Additional experiments relative to the shelf life of Li(Si)/FeS2 thermal batteries

    NASA Astrophysics Data System (ADS)

    Searcy, J. Q.; Armijo, J. R.

    1985-02-01

    A continuing effort to develop a new thermal battery technology based on the Li(Si)/FeS2 electrochemical couple is reported. The results relate to the long shelf life requirement for thermal batteries designed by Sandia, and include topics relevant to leakage through the hermetic seal and accelerated aging experiments with materials new to the technology. Conclusions relevant to leakage through the hermetic seal are that the maximum leak rate must not exceed 1.8 x 10(-7) w, where w is the grams of Li(Si) contained by a battery, and that a bomb type leak test can be designed that is adequate for most Li(Si)/FeS2 batteries. Conclusions relevant to long term compatibility of new materials include the following: nickel is not compatible with the iron disulfide in the cathode; the CaSi2 additive used to suppress the initial voltage transient does not react or degrade during accelerated aging experiments, but the use of that material can lead to an increase in the variability of the activated lives, especially for long life batteries; Grafoil current collectors used with the cathode do not degrade in accelerated aging experiments.

  19. Will Duct Tape and Plastic Really Work? Issues Related to Expedient Shelter-In-Place

    SciTech Connect

    Sorensen, J.H.

    2002-08-30

    Expedient sheltering involves the use of common materials to enhance the safety of a room inside a building against the impacts of a chemical plume. The central premise behind taping and sealing with duct tape and plastic is to reduce airflow into a room. This paper reviews issues associated with the use of expedient sheltering materials and the effectiveness of this strategy. Expedient sheltering provides additional protection to people sheltering in place beyond that provided by the house and by a safe room without expedient measures. The materials chosen for taping and sealing--duct tape and plastic--are appropriate because they effectively reduce infiltration and the materials should withstand a vapor challenge. Taping is essential to reduce air infiltration. Plastic sheeting is not a critical element for reducing air infiltration, but it makes sealing off large windows easier.

  20. Relative Importance and Additive Effects of Maternal and Infant Risk Factors on Childhood Asthma

    PubMed Central

    Rosas-Salazar, Christian; James, Kristina; Escobar, Gabriel; Gebretsadik, Tebeb; Li, Sherian Xu; Carroll, Kecia N.; Walsh, Eileen; Mitchel, Edward; Das, Suman; Kumar, Rajesh; Yu, Chang; Dupont, William D.; Hartert, Tina V.

    2016-01-01

    Background Environmental exposures that occur in utero and during early life may contribute to the development of childhood asthma through alteration of the human microbiome. The objectives of this study were to estimate the cumulative effect and relative importance of environmental exposures on the risk of childhood asthma. Methods We conducted a population-based birth cohort study of mother-child dyads who were born between 1995 and 2003 and were continuously enrolled in the PRIMA (Prevention of RSV: Impact on Morbidity and Asthma) cohort. The individual and cumulative impact of maternal urinary tract infections (UTI) during pregnancy, maternal colonization with group B streptococcus (GBS), mode of delivery, infant antibiotic use, and older siblings at home, on the risk of childhood asthma were estimated using logistic regression. Dose-response effect on childhood asthma risk was assessed for continuous risk factors: number of maternal UTIs during pregnancy, courses of infant antibiotics, and number of older siblings at home. We further assessed and compared the relative importance of these exposures on the asthma risk. In a subgroup of children for whom maternal antibiotic use during pregnancy information was available, the effect of maternal antibiotic use on the risk of childhood asthma was estimated. Results Among 136,098 singleton birth infants, 13.29% developed asthma. In both univariate and adjusted analyses, maternal UTI during pregnancy (odds ratio [OR] 1.2, 95% confidence interval [CI] 1.18, 1.25; adjusted OR [AOR] 1.04, 95%CI 1.02, 1.07 for every additional UTI) and infant antibiotic use (OR 1.21, 95%CI 1.20, 1.22; AOR 1.16, 95%CI 1.15, 1.17 for every additional course) were associated with an increased risk of childhood asthma, while having older siblings at home (OR 0.92, 95%CI 0.91, 0.93; AOR 0.85, 95%CI 0.84, 0.87 for each additional sibling) was associated with a decreased risk of childhood asthma, in a dose-dependent manner. Compared with vaginal

  1. Review of Cross-Cultural Issues Related to Quality of Life After Spinal Cord Injury

    PubMed Central

    Tate, Denise

    2014-01-01

    Quality of life (QOL) is a dynamic concept that means different things to different people, both in the general public and within the research community. Because of this, a common definition of QOL has been hard to achieve. This article reviews cross-cultural issues related to QOL research in spinal cord injury (SCI). Many factors influence QOL for persons with SCI, including observable and objective indicators and subjective self-report ones. The World Health Organization’s International Classification of Function, Disability and Health is used in this article as a framework to better understand how these factors may influence QOL. A number of important steps are summarized with respect to measurement issues in QOL. A comparison between data from 2 countries (United States and Brazil) using the International SCI QOL Basic Data Set shows similarities in scores and good reliability in the Brazilian sample. Substantial, significant correlations were observed among the SCI QOL Basic Data Set items and the WHOQOL-BREF within the US sample. The article ends with a set of recommendations for the development of cross-cultural measures of QOL for use in the SCI population. PMID:25484564

  2. Attitudes of cystic fibrosis patients and parents toward carrier screening and related reproductive issues.

    PubMed

    Janssens, Sandra; Chokoshvilli, Davit; Binst, Carmen; Mahieu, Inge; Henneman, Lidewij; De Paepe, Anne; Borry, Pascal

    2016-04-01

    Cystic fibrosis (CF) is a life-limiting autosomal recessive disorder affecting ~1 in 2500-4000 Caucasians. As most CF patients have no family history of the disorder, carrier screening for CF has the potential to prospectively identify couples at risk of conceiving an affected child. At-risk couples may consequently choose to act on the provided information and take steps to avoid the birth of a child with CF. Although carrier screening is widely believed to enhance reproductive autonomy of prospective parents, the practice also raises important ethical questions. A written questionnaire was administered to adult patients and parents of children with CF with the aim to explore participants' attitudes toward CF carrier screening and related reproductive issues. The study population was recruited from a CF patient registry in Belgium and comprised 111 participants (64 parents, 47 patients aged 16 or older). We found that more than 80% of all participants were in favor of preconception carrier screening for CF. However, some were concerned over potential negative consequences of population-wide CF carrier screening. Regarding future reproductive intentions, 43% of the participants indicated a desire to have children. Among these, preimplantation genetic diagnosis was found to be the most preferred reproductive option, closely followed by spontaneous pregnancy and prenatal diagnosis. Although the findings of our study suggest that patients and parents of children with CF support a population-based carrier screening program for CF, they also highlight some issues deserving particular attention when implementing such a program. PMID:26220700

  3. The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety

    PubMed Central

    Ekor, Martins

    2014-01-01

    The use of herbal medicinal products and supplements has increased tremendously over the past three decades with not less than 80% of people worldwide relying on them for some part of primary healthcare. Although therapies involving these agents have shown promising potential with the efficacy of a good number of herbal products clearly established, many of them remain untested and their use are either poorly monitored or not even monitored at all. The consequence of this is an inadequate knowledge of their mode of action, potential adverse reactions, contraindications, and interactions with existing orthodox pharmaceuticals and functional foods to promote both safe and rational use of these agents. Since safety continues to be a major issue with the use of herbal remedies, it becomes imperative, therefore, that relevant regulatory authorities put in place appropriate measures to protect public health by ensuring that all herbal medicines are safe and of suitable quality. This review discusses toxicity-related issues and major safety concerns arising from the use of herbal medicinal products and also highlights some important challenges associated with effective monitoring of their safety. PMID:24454289

  4. Addressing Work-Related Issues in Medical Rehabilitation: Revision of an Online Information Tool for Healthcare Professionals

    PubMed Central

    Wolf, Hans-Dieter; Gerlich, Christian; Vogel, Heiner; Neuderth, Silke

    2016-01-01

    Background. Medical rehabilitation increasingly considers occupational issues as determinants of health and work ability. Information on work-related rehabilitation concepts should therefore be made available to healthcare professionals. Objective. To revise a website providing healthcare professionals in medical rehabilitation facilities with information on work-related concepts in terms of updating existing information and including new topics, based on recommendations from implementation research. Method. The modification process included a questionnaire survey of medical rehabilitation centers (n = 28); two workshops with experts from rehabilitation centers, health payers, and research institutions (n = 14); the selection of new topics and revision of existing text modules based on expert consensus; and an update of good practice descriptions of work-related measures. Results. Health payers' requirements, workplace descriptions, and practical implementation aids were added as new topics. The database of good practice examples was extended to 63 descriptions. Information on introductory concepts was rewritten and supplemented by current data. Diagnostic tools were updated by including additional assessments. Conclusions. Recommendations from implementation research such as assessing user needs and including expert knowledge may serve as a useful starting point for the dissemination of information on work-related medical rehabilitation into practice. Web-based information tools such as the website presented here can be quickly adapted to current evidence and changes in medicolegal regulations. PMID:27610246

  5. Addressing Work-Related Issues in Medical Rehabilitation: Revision of an Online Information Tool for Healthcare Professionals.

    PubMed

    Lukasczik, Matthias; Wolf, Hans-Dieter; Gerlich, Christian; Küffner, Roland; Vogel, Heiner; Neuderth, Silke

    2016-01-01

    Background. Medical rehabilitation increasingly considers occupational issues as determinants of health and work ability. Information on work-related rehabilitation concepts should therefore be made available to healthcare professionals. Objective. To revise a website providing healthcare professionals in medical rehabilitation facilities with information on work-related concepts in terms of updating existing information and including new topics, based on recommendations from implementation research. Method. The modification process included a questionnaire survey of medical rehabilitation centers (n = 28); two workshops with experts from rehabilitation centers, health payers, and research institutions (n = 14); the selection of new topics and revision of existing text modules based on expert consensus; and an update of good practice descriptions of work-related measures. Results. Health payers' requirements, workplace descriptions, and practical implementation aids were added as new topics. The database of good practice examples was extended to 63 descriptions. Information on introductory concepts was rewritten and supplemented by current data. Diagnostic tools were updated by including additional assessments. Conclusions. Recommendations from implementation research such as assessing user needs and including expert knowledge may serve as a useful starting point for the dissemination of information on work-related medical rehabilitation into practice. Web-based information tools such as the website presented here can be quickly adapted to current evidence and changes in medicolegal regulations. PMID:27610246

  6. Soybean root growth in acid subsoils in relation to magnesium additions and soil solution ionic strength

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Hydroponic studies with soybean [Glycine max (L.) Merr.] have shown that µM additions of Mg2+ were as effective in ameliorating Al rhizotoxicity as additions of Ca2+ in the mM concentration range. The objectives of this study were to assess ameliorative effects of Mg on soybean root growth in acidic...

  7. Propagation characteristics of the ionospheric transmission window relating to long wave radio location issues

    NASA Astrophysics Data System (ADS)

    Kossey, Paul A.; Lewis, Edward A.

    1992-11-01

    Most applications of long radio waves (ELF/VLF/LF/MF) are ground-based and exploit the fact that such signals can propagate to great distances via reflections from the lower ionosphere. It is known however that, owing to the influence of the earth's magnetic field, long wave signals can penetrate through the ionosphere as well; at times, the waves penetrate with relatively little loss, depending on ionospheric conditions and other propagation factors. This has prompted investigations of the long wave 'ionospheric transmission window' as part of efforts to assess the feasibility of deploying long wave emitters in space for terrestrial applications and/or for exploiting, in space, signals emanating from ground-based long wave transmitters. This paper outlines results of theoretical and experimental investigations of the ionospheric transmission window over the frequency range from about 100 Hz to 500 kHz, with emphasis on directional issues associated with long wave penetration of the ionosphere.

  8. Impact of direct-to-consumer advertising (DTCA) on patient health-related behaviors and issues.

    PubMed

    Polen, Hyla H; Khanfar, Nile M; Clauson, Kevin A

    2009-01-01

    The pharmaceutical industry spends billions of dollars annually on direct-to-consumer advertising (DTCA). Patient perspectives on the impact of televised DTCA on health-related behaviors and issues were assessed by means of a 68-question survey. 58.6% of respondents believed that DTCA allowed consumers to have a more active role in managing their health. However, 27.6% felt DTCA caused confusion, and an alarming 17.8% of respondents stopped taking their medication because of concerns about serious side effects mentioned in DTCA. Overall, participants believed DTCA plays a useful role in health self-management; however, a considerable percentage thought that the cost outweighs the benefits. PMID:19197587

  9. Basic issues related to quantity and quality of health care, and quality assurance in Indonesia.

    PubMed

    Jacobalis, S

    1989-01-01

    Issues and problems related to the needs for quantity and quality in health care have been presented. The need for quantity has been quite successfully addressed in the last 20 years. Better quality of health care is very much in the minds of policy makers, providers and the informed public. Quality assessment and assurance as a programmed and on-going process in individual hospitals is systematically promoted and developed. An accreditation system for hospitals is planned for the future. This paper has not been able to contribute anything of value to the current practice of quality assurance. The industrialized world has passed the stages Indonesia is now going through. To some Australian colleagues, this presentation perhaps has revealed that one of their closest neighbours is struggling hard to improve the quality of life of its people, despite the tremendous problems and constraints with which it is confronted. Australia has always provided a helping hand in this struggle. PMID:2486044

  10. Issues related to symptomatic and disease-modifying treatments affecting cognitive and neuropsychiatric comorbidities of epilepsy.

    PubMed

    Brooks-Kayal, Amy R; Bath, Kevin G; Berg, Anne T; Galanopoulou, Aristea S; Holmes, Gregory L; Jensen, Frances E; Kanner, Andres M; O'Brien, Terence J; Whittemore, Vicky H; Winawer, Melodie R; Patel, Manisha; Scharfman, Helen E

    2013-08-01

    Many symptoms of neurologic or psychiatric illness--such as cognitive impairment, depression, anxiety, attention deficits, and migraine--occur more frequently in people with epilepsy than in the general population. These diverse comorbidities present an underappreciated problem for people with epilepsy and their caregivers because they decrease quality of life, complicate treatment, and increase mortality. In fact, it has been suggested that comorbidities can have a greater effect on quality of life in people with epilepsy than the seizures themselves. There is increasing recognition of the frequency and impact of cognitive and behavioral comorbidities of epilepsy, highlighted in the 2012 Institute of Medicine report on epilepsy. Comorbidities have also been acknowledged, as a National Institutes of Health (NIH) Benchmark area for research in epilepsy. However, relatively little progress has been made in developing new therapies directed specifically at comorbidities. On the other hand, there have been many advances in understanding underlying mechanisms. These advances have made it possible to identify novel targets for therapy and prevention. As part of the International League Against Epilepsy/American Epilepsy Society workshop on preclinical therapy development for epilepsy, our working group considered the current state of understanding related to terminology, models, and strategies for therapy development for the comorbidities of epilepsy. Herein we summarize our findings and suggest ways to accelerate development of new therapies. We also consider important issues to improve research including those related to methodology, nonpharmacologic therapies, biomarkers, and infrastructure. PMID:23909853

  11. Some folded issues related to over-shielded and unplanned rooms for medical linear accelerators - A case study

    NASA Astrophysics Data System (ADS)

    Muhammad, Wazir; Ullah, Asad; Hussain, Amjad; Ali, Nawab; Alam, Khan; Khan, Gulzar; Matiullah; Maeng, Seongjin; Lee, Sang Hoon

    2015-08-01

    A medical linear accelerator (LINAC) room must be properly shielded to limit the outside radiation exposure to an acceptable safe level defined by individual state and international regulations. However, along with this prime objective, some additional issues are also important. The current case-study was designed to unfold the issues related to over-shielded and unplanned treatment rooms for LINACs. In this connection, an apparently unplanned and over-shielded treatment room of 610 × 610 cm2 in size was compared with a properly designed treatment room of 762 × 762 cm2 in size ( i.e., by following the procedures and recommendations of the IAEA Safety Reports Series No. 47 and NCRP 151). Evaluation of the unplanned room indicated that it was over-shielded and that its size was not suitable for total body irradiation (TBI), although the license for such a treatment facility had been acquired for the installed machine. An overall 14.96% reduction in the total shielding volume ( i.e., concrete) for an optimally planned room as compared to a non-planned room was estimated. Furthermore, the inner room's dimensions were increased by 25%, in order to accommodate TBI patients. These results show that planning and design of the treatment rooms are imperative to avoid extra financial burden to the hospitals and to provide enough space for easy and safe handling of the patients. A spacious room is ideal for storing treatment accessories and facilitates TBI treatment.

  12. Addressing weight-related issues in an elementary school: what do students, parents, and school staff recommend?

    PubMed

    Haines, Jess; Neumark-Sztainer, Dianne; Thiel, Lynnell

    2007-01-01

    This study examined weight-related issues affecting elementary school children to gain insight into how best to address these issues within a school-based intervention. The study population included 21 students, 12 school staff members, and 21 parents from a school that serves an ethnically-diverse population. Data were collected using focus groups and individual interviews and were analyzed using qualitative research methodology. Weight-related teasing and poor body image emerged as prominent issues affecting students. Results suggest that programs aimed at the prevention of weight-related disorders should go beyond issues of nutrition and physical activity and include strategies to reduce weight-related mistreatment and to improve students' body image. PMID:17162638

  13. Feminizing genitoplasty: a synopsis of issues relating to genital surgery in intersex individuals.

    PubMed

    Schober, Justine M

    2004-05-01

    This review of the literature relevant to genitoplasty explores multiple factors that could impact and improve long-term outcomes. In 1998, surgeons began a dialogue that fostered interactive multidisciplinary exchanges regarding necessity, timing, and risks related to genitoplasty. Prior practice had embraced a simplistic approach--make an intersexed child resemble either a typical boy or girl. But surgery was never 'perfect' because function was often sacrificed for form, the goal being to create an aesthetic appearance. Compounding the difficulties of this type of surgery were the demands of the patients and parents for clarity, sure direction, and surgery that looked cosmetically authentic and provided good function. They demanded answers that medical experts could not readily provide regarding long-term outcomes. To increase patient satisfaction, we seek such outcomes and knowledge to better our understanding for optimal patient management and care. A review of current research is provided that might have important implications impacting surgical issues. Knowledge garnered from fields other than surgery is explored for potential applications that could improve surgical outcomes. Surgical technique modifications may be part of the solution to a complex problem, but they are not the sole solution. A multidisciplinary approach is required because to this date, surgical promise is limited at best. Better understanding of the anatomy and physiology, as well as the related hormonal environment and its impact on healing, may be the key toward improvement of outcomes and heightened patient satisfaction. PMID:15237702

  14. Application of Radiation Chemistry to Some Selected Technological Issues Related to the Development of Nuclear Energy.

    PubMed

    Bobrowski, Krzysztof; Skotnicki, Konrad; Szreder, Tomasz

    2016-10-01

    The most important contributions of radiation chemistry to some selected technological issues related to water-cooled reactors, reprocessing of spent nuclear fuel and high-level radioactive wastes, and fuel evolution during final radioactive waste disposal are highlighted. Chemical reactions occurring at the operating temperatures and pressures of reactors and involving primary transients and stable products from water radiolysis are presented and discussed in terms of the kinetic parameters and radiation chemical yields. The knowledge of these parameters is essential since they serve as input data to the models of water radiolysis in the primary loop of light water reactors and super critical water reactors. Selected features of water radiolysis in heterogeneous systems, such as aqueous nanoparticle suspensions and slurries, ceramic oxides surfaces, nanoporous, and cement-based materials, are discussed. They are of particular concern in the primary cooling loops in nuclear reactors and long-term storage of nuclear waste in geological repositories. This also includes radiation-induced processes related to corrosion of cladding materials and copper-coated iron canisters, dissolution of spent nuclear fuel, and changes of bentonite clays properties. Radiation-induced processes affecting stability of solvents and solvent extraction ligands as well oxidation states of actinide metal ions during recycling of the spent nuclear fuel are also briefly summarized. PMID:27573502

  15. Bisphosphonate-Related Osteonecrosis of the Jaw: Historical, Ethical, and Legal Issues Associated With Prescribing

    PubMed Central

    Faiman, Beth; Pillai, Aiswarya Lekshmi Pillai Chandran; Benghiac, Ana Gabriela

    2013-01-01

    The long-term effects of many drugs are unknown. Established risks are communicated to patients who participate in clinical trials during the informed consent process. However, unknown and unanticipated side effects of medications may occur years after treatment. Patients with metastatic bone cancer experience an imbalance between tumor cells and the bone marrow microenvironment. Increased cytokine release, osteoclastic activity, and uncoupled osteoblastic activity lead to weakened bone structure and osteolytic lesions. The bisphosphonates are a class of drugs available in IV and oral formulations to treat and prevent bone loss and decrease the risk of skeletal-related events. Intravenous bisphosphonates such as zoledronic acid and pamidronate disodium are approved by the US Food and Drug Administration for the treatment of bone pain and hypercalcemia of malignancy and the prevention of painful bone fractures in patients with metastatic bone cancer. Oral bisphosphonates such as alendronate, risedronate, and etidronate are used to reduce the risk of skeletal fractures in patients with osteoporosis and in breast cancer. Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a rare but painful complication of treatment characterized by infection, exposed bone, and poor wound healing. In this article, we discuss BRONJ and identify past, present, and future ethical and legal issues surrounding bisphosphonate administration. PMID:25031978

  16. Studies of levels of biogenic amines in meat samples in relation to the content of additives.

    PubMed

    Jastrzębska, Aneta; Kowalska, Sylwia; Szłyk, Edward

    2016-01-01

    The impact of meat additives on the concentration of biogenic amines and the quality of meat was studied. Fresh white and red meat samples were fortified with the following food additives: citric and lactic acids, disodium diphosphate, sodium nitrite, sodium metabisulphite, potassium sorbate, sodium chloride, ascorbic acid, α-tocopherol, propyl 3,4,5-trihydroxybenzoate (propyl gallate) and butylated hydroxyanisole. The content of spermine, spermidine, putrescine, cadaverine, histamine, tyramine, tryptamine and 2-phenylethylamine was determined by capillary isotachophoretic methods in meat samples (fresh and fortified) during four days of storage at 4°C. The results were applied to estimate the impact of the tested additives on the formation of biogenic amines in white and red meat. For all tested meats, sodium nitrite, sodium chloride and disodium diphosphate showed the best inhibition. However, cadaverine and putrescine were characterised by the biggest changes in concentration during the storage time of all the additives. Based on the presented data for the content of biogenic amines in meat samples analysed as a function of storage time and additives, we suggest that cadaverine and putrescine have a significant impact on meat quality. PMID:26515667

  17. Summary of tank information relating salt well pumping to flammable gas safety issues

    SciTech Connect

    Caley, S.M.; Mahoney, L.A.; Gauglitz, P.A.

    1996-09-01

    The Hanford Site has 149 single-shell tanks (SSTs) containing radioactive wastes that are complex mixes of radioactive and chemical products. Active use of these SSTs was phased out completely by November 1980, and the first step toward final disposal of the waste in the SSTs is interim stabilization, which involves removing essentially all of the drainable liquid from the tank. Stabilization can be achieved administratively, by jet pumping to remove drainable interstitial liquid, or by supernatant pumping. To date, 116 tanks have been declared interim stabilized; 44 SSTs have had drainable liquid removed by salt well jet pumping. Of the 149 SSTs, 19 are on the Flammable Gas Watch List (FGWL) because the waste in these tanks is known or suspected, in all but one case, to generate and retain mixtures of flammable gases, including; hydrogen, nitrous oxide, and ammonia. Salt well pumping to remove the drainable interstitial liquid from these SSTs is expected to cause the release of much of the retained gas, posing a number of safety concerns. The scope of this work is to collect and summarize information, primarily tank data and observations, that relate salt well pumping to flammable gas safety issues. While the waste within FGWL SSTs is suspected offering flammable gases, the effect of salt well pumping on the waste behavior is not well understood. This study is being conducted for the Westinghouse Hanford Company as part of the Flammable Gas Project at the Pacific Northwest National Laboratory (PNNL). Understanding the historical tank behavior during and following salt well pumping will help to resolve the associated safety issues.

  18. Marketing nutrition & health-related benefits of food & beverage products: enforcement, litigation & liability issues.

    PubMed

    Roller, Sarah; Pippins, Raqiyyah

    2010-01-01

    Over the past decade, the liability risks associated with food and beverage product marketing have increased significantly, particularly with respect to nutrition and health-related product benefit claims. FDA and FTC enforcement priorities appear to have contributed to the increasing liability trends that are associated with these nutrition and health-related claims. This article examines key enforcement and litigation developments involving conventional food and beverage product marketing claims during the first 18 months of President Obama's administration: Part I considers FDA enforcement priorities and recent warning letters; Part II considers FTC enforcement priorities, warning letters, and consent orders; and Part III considers the relationship between FDA and FTC enforcement priorities and recent false advertising cases brought by private parties challenging nutrition and health-related marketing claims for food and beverage products. The article makes recommendations concerning ways in which food and beverage companies can help minimize liability risks associated with health-related marketing claims. In addition, the article suggests that federal policy reforms may be required to counter the perverse chilling effects current food liability trends appear to be having on health-related marketing claims for food and beverage products, and proposes a number of specific reforms that would help encourage the responsible use of well-substantiated marketing claims that can help foster healthy dietary practices. In view of the obesity prevention and other diet-related public health priorities of the Obama administration, the article suggests that this is an opportune time to address the apparent chilling effects increasing food liability risks are having on nutrition and health-related marketing claims for healthy food and beverage products, and potential adverse consequences for public health. PMID:24479235

  19. 47 CFR 5.311 - Additional requirements related to safety of the public.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... safety of the public. In addition to the notification requirements of § 5.309, for experiments that may... bands and geographic area as the planned experiment and, as appropriate, their end users; (b) Rapid identification, and elimination, of any harm the experiment may cause; and (c) Identifying an alternate means...

  20. 47 CFR 5.311 - Additional requirements related to safety of the public.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... safety of the public. In addition to the notification requirements of § 5.309, for experiments that may... bands and geographic area as the planned experiment and, as appropriate, their end users; (b) Rapid identification, and elimination, of any harm the experiment may cause; and (c) Identifying an alternate means...

  1. Relations among Parental Alcoholism, Eating Disorders, and Substance Abuse in Nonclinical College Women: Additional Evidence against the Uniformity Myth.

    ERIC Educational Resources Information Center

    Mintz, Laurie B.; And Others

    1995-01-01

    The relationship of parental alcoholism to eating disorder symptomology and substance abuse in a nonclinical sample of college women was examined. In addition, differences among adult children of alcoholics (ACOAs) related to level of distress concerning parental alcohol use was examined. Results add additional evidence to the notion that not all…

  2. Hypertension and related health issues among Asians and Pacific Islanders in California.

    PubMed Central

    Stavig, G R; Igra, A; Leonard, A R

    1988-01-01

    The prevalence of controlled and uncontrolled hypertension in the United States is lower for persons ethnically classified as Asian, particularly Japanese and excepting Filipinos, than for the general population. In this study, measurements of blood pressure were taken of 8,353 adults living in California, including 1,757 Asians and Pacific Islanders, and the subjects were asked six questions concerning high blood pressure. The results show that Asians and Pacific Islanders with hypertension, in comparison with hypertensive persons of other races, were less likely to be aware of their hypertension, to be under treatment with medication, and to be controlling their blood pressure; similarly, they had their blood pressure measured less frequently and visited physicians less often. Compared with the general population, Asians and Pacific Islanders were less knowledgeable about hypertension. In relation to health care, they recorded lower frequencies of hospital stays, days of bed disabilities, and days of not feeling well than persons of other races. Asians and Pacific Islanders' lower treatment rates and knowledge level concerning hypertension may be related to the fact that a high percentage are foreign-born. Consequently, they have been taught less about hypertension, rely more on traditional methods of medicine, and are hampered by the lack of availability of health care providers of their own ethnic background. In addition, Filipinos have experienced high levels of poverty and lack of education. These factors require additional study as part of efforts to help improve health care for these ethnic groups in the United States. PMID:3124194

  3. Vocational technical and adult education: Status, trends and issues related to electronic delivery

    NASA Technical Reports Server (NTRS)

    Rothenberg, D.

    1973-01-01

    Data are analyzed, and trends and issues are discussed to provide information useful to the systems designer who wishes to identify and assess the opportunities for large scale electronic delivery in vocational/technical and adult education. Issues connected with vocational/technical education are investigated, with emphasis on those issues in the current spotlight which are relevant to the possibilities of electronic delivery. The current role of media is examined in vocational/technical instruction.

  4. Feed- and feed additives-related aspects of gut health and development in weanling pigs.

    PubMed

    Pluske, John R

    2013-01-01

    The development of new/different management and feeding strategies to stimulate gut development and health in newly-weaned pigs, in order to improve growth performance while minimizing the use of antimicrobial compounds such as antibiotic growth promotants (AGP) and heavy mineral compounds, is essential for the long-term sustainability of the pig industry. Factors including the sub-optimal intake of nutrients and energy, inappropriate microbiota biomass and (or) balance, immature and compromised immune function, and psychosomatic factors caused by weaning can compromise both the efficiency of digestion and absorption and intestinal barrier function through mucosal damage and alteration of tight junction integrity. As a consequence, pigs at weaning are highly susceptible to pathogenic enteric conditions such as post-weaning diarrhea that may be caused by serotypes of enterotoxigenic Escherichia coli. Many dietary components, e.g., protein, fiber, feed additives and minerals, are known to influence microbial growth in the gastrointestinal tract that in turn can impact upon pig growth and health, although the relationships between these are sometimes not necessarily apparent or obvious. In a world climate of increased scrutiny over the use of antibiotics per se in pig production, certain feed additives are seen as alternatives/replacements to antibiotics, and have evolved in some cases to have important roles in everyday commercial pig nutrition. Nevertheless and in general, there remains inconsistency and variability in the efficacy of some feed additives and in cases of severe disease outbreaks, for example, therapeutic antibiotics and/or heavy minerals such as zinc oxide (ZnO) are generally relied upon. If feed ingredients and (or) feed additives are to be used with greater regularity and reliability, then it is necessary to better understand the mechanisms whereby antibiotics and minerals such as ZnO influence animal physiology, in conjunction with the use of

  5. Feed- and feed additives-related aspects of gut health and development in weanling pigs

    PubMed Central

    2013-01-01

    The development of new/different management and feeding strategies to stimulate gut development and health in newly-weaned pigs, in order to improve growth performance while minimizing the use of antimicrobial compounds such as antibiotic growth promotants (AGP) and heavy mineral compounds, is essential for the long-term sustainability of the pig industry. Factors including the sub-optimal intake of nutrients and energy, inappropriate microbiota biomass and (or) balance, immature and compromised immune function, and psychosomatic factors caused by weaning can compromise both the efficiency of digestion and absorption and intestinal barrier function through mucosal damage and alteration of tight junction integrity. As a consequence, pigs at weaning are highly susceptible to pathogenic enteric conditions such as post-weaning diarrhea that may be caused by serotypes of enterotoxigenic Escherichia coli. Many dietary components, e.g., protein, fiber, feed additives and minerals, are known to influence microbial growth in the gastrointestinal tract that in turn can impact upon pig growth and health, although the relationships between these are sometimes not necessarily apparent or obvious. In a world climate of increased scrutiny over the use of antibiotics per se in pig production, certain feed additives are seen as alternatives/replacements to antibiotics, and have evolved in some cases to have important roles in everyday commercial pig nutrition. Nevertheless and in general, there remains inconsistency and variability in the efficacy of some feed additives and in cases of severe disease outbreaks, for example, therapeutic antibiotics and/or heavy minerals such as zinc oxide (ZnO) are generally relied upon. If feed ingredients and (or) feed additives are to be used with greater regularity and reliability, then it is necessary to better understand the mechanisms whereby antibiotics and minerals such as ZnO influence animal physiology, in conjunction with the use of

  6. Problems Related to the Use of Food Additives in the United States

    PubMed Central

    Oser, Bernard L.

    1966-01-01

    Major problems encountered by enforcement agencies and by regulated industries, respectively, in implementing and conforming to recent food additive laws are reviewed. Decisions as to which substances fall within the broad terms of the legal definition, and which escape by virtue of “generally recognized as safe” (GRAS) status, are often difficult and complex. Distinctions cannot be made solely on the basis of whether substances are old or new, natural or synthetic. Registration of pesticides on a “no residue” basis and establishment of “zero tolerances” for food additives have created an anomalous situation as a result of improvements in sensitivity of analytical techniques which revealed the presence of minute amounts of substances where none were believed to exist. A solution has been recommended by a specially appointed committee of the National Academy of Sciences-National Research Council (U.S.A.). Enforcement of the new food additive laws warrants revision of present labelling requirements to provide for designating chemical ingredients by functional categories rather than by confusing chemical terminology.

  7. Health, safety and environmental issues relating to cadmium usage in photovoltaic energy systems

    SciTech Connect

    Moskowitz, P.D.; Fthenakis, V.M. ); Zweibel, K. )

    1989-12-01

    This paper discusses the current technology base and hazards associated with two promising thin-film photovoltaic cells that contain cadmium compounds -- cadmium telluride (CdTe) and copper indium diselenide (CuInSe{sub 2}). More specifically, this paper summarizes the toxicological information on cadmium (Cd) compounds; evaluates potential health, safety and environmental hazards associated with cadmium usage in the photovoltaics industry; describes regulatory requirements associated with the use, handling and disposal of cadmium compounds; and lists management options to permit the safe and continued use of these materials. Handling of cadmium in photovoltaic production can present hazards to health, safety and the environment. Prior recognition of these hazards can allow device manufacturers and regulators to implement appropriate and readily available hazard management strategies. Hazards associated with product use (i.e., array fires) and disposal remain controversial and partially unresolved. The most likely effects that could be expected would be those associated with chronic low-level exposures to cadmium wastes. Because of the general immobility of the cadmium present in these devices and availability of environmental and biomonitoring protocols, chronic hazards can be monitored, and remediated if necessary. Nevertheless, concern about cadmium hazards should continue to be emphasized to ensure that health, safety and environmental issues are properly managed. At the same time, the potential role that these systems can play in ameliorating some important health and environmental hazards related to other energy systems should not be ignored. 27 refs., 5 figs., 2 tabs.

  8. Xylitol: a review on bioproduction, application, health benefits, and related safety issues.

    PubMed

    Ur-Rehman, Salim; Mushtaq, Zarina; Zahoor, Tahir; Jamil, Amir; Murtaza, Mian Anjum

    2015-01-01

    Xylitol is a pentahydroxy sugar-alcohol which exists in a very low quantity in fruits and vegetables (plums, strawberries, cauliflower, and pumpkin). On commercial scale, xylitol can be produced by chemical and biotechnological processes. Chemical production is costly and extensive in purification steps. However, biotechnological method utilizes agricultural and forestry wastes which offer the possibilities of economic production of xylitol by reducing required energy. The precursor xylose is produced from agricultural biomass by chemical and enzymatic hydrolysis and can be converted to xylitol primarily by yeast strain. Hydrolysis under acidic condition is the more commonly used practice influenced by various process parameters. Various fermentation process inhibitors are produced during chemical hydrolysis that reduce xylitol production, a detoxification step is, therefore, necessary. Biotechnological xylitol production is an integral process of microbial species belonging to Candida genus which is influenced by various process parameters such as pH, temperature, time, nitrogen source, and yeast extract level. Xylitol has application and potential for food and pharmaceutical industries. It is a functional sweetener as it has prebiotic effects which can reduce blood glucose, triglyceride, and cholesterol level. This review describes recent research developments related to bioproduction of xylitol from agricultural wastes, application, health, and safety issues. PMID:24915309

  9. Efficacy of combining interview techniques in detecting deception related to bio-threat issues.

    PubMed

    Morgan, Charles A; Rabinowitz, Yaron; Leidy, Robert; Coric, Vladimir

    2014-01-01

    The purpose of this project was to assess the detecting deception efficacy of three well-validated "detecting deception" methods - i.e., forced choice testing (FCT), modified cognitive interviewing (MCI) and autobiographical implicit association testing (aIAT) - when applied to the issue of bio-threat. The detecting deception accuracies of FCT and MCI were 81% and 75%, respectively. Although the aIAT mean response times in block 5 differed significantly between deceptive and truthful persons, the classification accuracy was low. FCT alone reduced the group of 64 persons to 11 and detected 50% of the liars; the false positive rate was 9%. MCI alone reduced the group of 64 to 24 and detected 92% of the liars; the false positive rate was 54%. When FCT was paired with MCI, 75% of liars were detected and the false positive rate was 13%. Forced choice testing and MCI show promise as methods for detecting deception related to bio-threat under low-base-rate conditions. These methods took little time, enhanced the odds of detecting deceptive individuals and exhibited high positive likelihood ratios, suggesting that they have merit as screening tools. The aIAT required more time and was less accurate but may still serve as a useful screening tool. PMID:24549687

  10. A discussion of issues related to hydrogeology of deep geologic systems

    NASA Astrophysics Data System (ADS)

    Tsang, C. F.; Niemi, A.

    2012-04-01

    The state of the deep hydrogeological system, including its hydraulic structures and flow patterns, distribution of permeability and porosity, and distribution of hydraulic head values, is very much an open research field. Much work needs to be done to obtain such data and to understand the current conditions at depth. Deep drilling projects worldwide have often been dominated by studies concerning the geological and geophysical processes, as well as the geochemical composition of the deep underground. Hydrogeological processes, on the other hand, have received relatively less attention. Yet many of the important chemical, thermal and mechanical processes of the deep underground are closely linked and cannot be properly addressed without an adequate understanding of fluid flow and solute migration. Hydrologic condition and its evolution may also play a significant role in long term geologic processes, such as orogenesis. Presently, intended to be part of the International Continental Drilling Program (ICDP), a deep drilling project is under preparation on the Swedish Caledonides (www.sddp.se/cosc), with the objective to address, among other things, issues related to fluid flow and solute migration. Partly prompted by this project, and partly by the desire to compile the existing knowledge, a workshop was convened in September 2011 in Uppsala, Sweden, to review the state-of-the-art of hydrogeological studies of deep systems, both from the point of view of available observations and data, and from the point of view of modeling and generic conceptual considerations. The discussions and presentations were structured around the following topics: (1) Spatial Extent and Dynamics of the Fluid Flow in the Deep Subsurface; (2) Fluid Flow in Coupled Thermo-Hydro-Mechanical-Chemical Processes occurring at depth; and (3) Monitoring and Modeling Methods. The present talk will aim to present the main outcomes and recommendations from this workshop.

  11. Public health issues related with the consumption of food obtained from genetically modified organisms.

    PubMed

    Paparini, Andrea; Romano-Spica, Vincenzo

    2004-01-01

    Genetically Modified Organisms (GMOs) are a fact of modern agriculture and a major field of discussion in biotechnology. As science incessantly achieves innovative and unexpected breakthroughs, new medical, political, ethical and religious debates arise over the production and consumption of transgenic organisms. Despite no described medical condition being directly associated with a diet including approved GM crops in large exposed populations such as 300,000,000 Americans and a billion Chinese, public opinion seems to look at this new technology with either growing concern or even disapproval. It is generally recognized that a high level of vigilance is necessary and highly desirable, but it should also be considered that GMOs are a promising new challenge for the III Millennium societies, with remarkable impact on many disciplines and fields related to biotechnology. To acquire a basic knowledge on GMO production, GM-food consumption, GMO interaction with humans and environment is of primary importance for risk assessment. It requires availability of clear data and results from rigorous experiments. This review will focus on public health risks related with a GMO-containing diet. The objective is to summarize state of the art research, provide fundamental technical information, point out problems and perspectives, and make available essential tools for further research. Are GMO based industries and GMO-derived foods safe to human health? Can we consider both social, ethical and public health issues by means of a constant and effective monitoring of the food chain and by a clear, informative labeling of the products? Which are the so far characterized or alleged hazards of GMOs? And, most importantly, are these hazards actual, potential or merely contrived? Several questions remain open; answers and solutions belong to science, to politics and to the personal opinion of each social subject. PMID:15504704

  12. 36 CFR 1237.14 - What are the additional scheduling requirements for audiovisual, cartographic, and related records?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... creation (see also 36 CFR part 1235). See § 1235.42 of this subchapter for specifications and standards for... scheduling requirements for audiovisual, cartographic, and related records? 1237.14 Section 1237.14 Parks..., CARTOGRAPHIC, AND RELATED RECORDS MANAGEMENT § 1237.14 What are the additional scheduling requirements...

  13. Addressing Individual Difficulties in Reading: Issues Relating to Reading Recovery and Pause, Prompt, Praise

    ERIC Educational Resources Information Center

    Wearmouth, Janice

    2004-01-01

    Recently the DfES has issued guidance on ways to address the needs of students who experience difficulties in literacy through Wave Three provision in the National Literacy Strategy (DfES, 2002). This guidance raises the issue of what kind of programmes might be initiated in mainstream schools that will improve what is available generally for…

  14. Confronting the Unknown: Principal Preparation Training in Issues Related to Special Education

    ERIC Educational Resources Information Center

    Angelle, Pamela; Bilton, Lisa M.

    2009-01-01

    This study examines principal preparation programs from the perspective of readiness to confront and/or support special education issues at the school building level. The purpose of this research was to answer the following questions: (1) What is the principal's readiness level upon program completion in dealing with special education issues in…

  15. Current Issues Related to Associate Degree Nursing: Their Impact on Directors, Faculty, and Students.

    ERIC Educational Resources Information Center

    Cavenar, Mary G.

    Perceptions of students, faculty members, and associate degree nursing (ADN) program directors/coordinators concerning seven issues affecting ADN programs were obtained in 1982. The issues, which were identified through a review of the literature, were: entry into practice, professional and technical nurses, developing competency statements,…

  16. Community ChoiceWork: Citizen Deliberations on Issues Related to HIV/AIDS.

    ERIC Educational Resources Information Center

    Charles, Chanya

    This guide describes Community ChoiceWork, an approach to directly involving citizens in issues that affect them (in this case, HIV/AIDS). It is intended help citizens frame and deliberate on an issue of concern that has no clear solution. After explaining what Community ChoiceWork is, the guide discusses what it has to do with HIV/AIDS. Next, it…

  17. Roadmapping - A Tool for Resolving Science and Technology Issues Related to Processing, Packaging, and Shipping Nuclear Materials and Waste

    SciTech Connect

    Luke, Dale Elden; Dixon, Brent Wayne; Murphy, James Anthony

    2002-06-01

    Roadmapping is an effective methodology to identify and link technology development and deployment efforts to a program's or project's needs and requirements. Roadmapping focuses on needed technical support to the baselines (and to alternatives to the baselines) where the probability of success is low (high uncertainty) and the consequences of failure are relatively high (high programmatic risk, higher cost, longer schedule, or higher ES&H risk). The roadmap identifies where emphasis is needed, i.e., areas where investments are large, the return on investment is high, or the timing is crucial. The development of a roadmap typically involves problem definition (current state versus the desired state) and major steps (functions) needed to reach the desired state. For Nuclear Materials (NM), the functions could include processing, packaging, storage, shipping, and/or final disposition of the material. Each function is examined to determine what technical development would be needed to make the function perform as desired. This requires a good understanding of the current state of technology and technology development and validation activities to ensure the viability of each step. In NM disposition projects, timing is crucial! Technology must be deployed within the project window to be of value. Roadmaps set the stage to keep the technology development and deployment focused on project milestones and ensure that the technologies are sufficiently mature when needed to mitigate project risk and meet project commitments. A recent roadmapping activity involved a 'cross-program' effort, which included NM programs, to address an area of significant concern to the Department of Energy (DOE) related to gas generation issues, particularly hydrogen. The roadmap that was developed defined major gas generation issues within the DOE complex and research that has been and is being conducted to address gas generation concerns. The roadmap also provided the basis for sharing ''lessons

  18. 26 CFR 1.6033-3 - Additional provisions relating to private foundations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... foundations. 1.6033-3 Section 1.6033-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... provisions relating to private foundations. (a) In general. The foundation managers (as defined in section... treated as) a private foundation (as defined in section 509) the assets of which are at least $5,000...

  19. 26 CFR 1.6033-3 - Additional provisions relating to private foundations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... foundations. 1.6033-3 Section 1.6033-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... provisions relating to private foundations. (a) In general. The foundation managers (as defined in section... treated as) a private foundation (as defined in section 509) the assets of which are at least $5,000...

  20. 26 CFR 1.6033-3 - Additional provisions relating to private foundations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... foundations. 1.6033-3 Section 1.6033-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... provisions relating to private foundations. (a) In general. The foundation managers (as defined in section... treated as) a private foundation (as defined in section 509) the assets of which are at least $5,000...

  1. 26 CFR 1.6033-3 - Additional provisions relating to private foundations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... foundations. 1.6033-3 Section 1.6033-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... provisions relating to private foundations. (a) In general. The foundation managers (as defined in section... treated as) a private foundation (as defined in section 509) the assets of which are at least $5,000...

  2. EFFECT OF RELATIVE HUMIDITY AND ADDITIVES ON THE REACTION OF SULFUR DIOXIDE WITH CALCIUM HYDROXIDE

    EPA Science Inventory

    The paper gives results of a study of the reaction of SO2 with Ca(OH)2 at conditions similar to those of commercial-scale bag filters: 19-74 percent relative humidity (RH), 30.4-95 C, and 300-4000 ppm SO2. The study was carried out in a bench-scale reactor with powder reagent Ca(...

  3. RECENT ADDITIONS OF CRITICALITY SAFETY RELATED INTEGRAL BENCHMARK DATA TO THE ICSBEP AND IRPHEP HANDBOOKS

    SciTech Connect

    J. Blair Briggs; Lori Scott; Yolanda Rugama; Enrico Sartori

    2009-09-01

    High-quality integral benchmark experiments have always been a priority for criticality safety. However, interest in integral benchmark data is increasing as efforts to quantify and reduce calculational uncertainties accelerate to meet the demands of future criticality safety needs to support next generation reactor and advanced fuel cycle concepts. The importance of drawing upon existing benchmark data is becoming more apparent because of dwindling availability of critical facilities worldwide and the high cost of performing new experiments. Integral benchmark data from the International Handbook of Evaluated Criticality Safety Benchmark Experiments and the International Handbook of Reactor Physics Benchmark Experiments are widely used. Benchmark data have been added to these two handbooks since the last Nuclear Criticality Safety Division Topical Meeting in Knoxville, Tennessee (September 2005). This paper highlights these additions.

  4. Hot Jupiters with relatives: discovery of additional planets in orbit around WASP-41 and WASP-47

    NASA Astrophysics Data System (ADS)

    Neveu-VanMalle, M.; Queloz, D.; Anderson, D. R.; Brown, D. J. A.; Collier Cameron, A.; Delrez, L.; Díaz, R. F.; Gillon, M.; Hellier, C.; Jehin, E.; Lister, T.; Pepe, F.; Rojo, P.; Ségransan, D.; Triaud, A. H. M. J.; Turner, O. D.; Udry, S.

    2016-02-01

    We report the discovery of two additional planetary companions to WASP-41 and WASP-47. WASP-41 c is a planet of minimum mass 3.18 ± 0.20 MJup and eccentricity 0.29 ± 0.02, and it orbits in 421 ± 2 days. WASP-47 c is a planet of minimum mass 1.24 ± 0.22 MJup and eccentricity 0.13 ± 0.10, and it orbits in 572 ± 7 days. Unlike most of the planetary systems that include a hot Jupiter, these two systems with a hot Jupiter have a long-period planet located at only ~1 au from their host star. WASP-41 is a rather young star known to be chromospherically active. To differentiate its magnetic cycle from the radial velocity effect induced by the second planet, we used the emission in the Hα line and find this indicator well suited to detecting the stellar activity pattern and the magnetic cycle. The analysis of the Rossiter-McLaughlin effect induced by WASP-41 b suggests that the planet could be misaligned, though an aligned orbit cannot be excluded. WASP-47 has recently been found to host two additional transiting super Earths. With such an unprecedented architecture, the WASP-47 system will be very important for understanding planetary migration. Using data collected at ESO's La Silla Observatory, Chile: HARPS on the ESO 3.6 m (Prog ID 087.C-0649 & 089.C-0151), the Swiss Euler Telescope, TRAPPIST, the 1.54-m Danish telescope (Prog CN2013A-159), and at the LCOGT's Faulkes Telescope South.Photometric lightcurve and RV tables are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/586/A93

  5. An Issue Hiding in Plain Sight: When Are Speech-Language Pathologists Special Educators Rather than Related Services Providers?

    ERIC Educational Resources Information Center

    Giangreco, Michael F.; Prelock, Patricia A.; Turnbull, H. Rutherford, III

    2010-01-01

    Purpose: Under the Individuals With Disabilities Education Act (IDEA; as amended, 2004), speech-language pathology services may be either special education or a related service. Given the absence of guidance documents or research on this issue, the purposes of this clinical exchange are to (a) present and analyze the IDEA definitions related to…

  6. 43 CFR 2931.2 - What kinds of permits does BLM issue for recreation-related uses of public lands?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false What kinds of permits does BLM issue for recreation-related uses of public lands? 2931.2 Section 2931.2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE...

  7. 43 CFR 2931.2 - What kinds of permits does BLM issue for recreation-related uses of public lands?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false What kinds of permits does BLM issue for recreation-related uses of public lands? 2931.2 Section 2931.2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE...

  8. 43 CFR 2931.2 - What kinds of permits does BLM issue for recreation-related uses of public lands?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false What kinds of permits does BLM issue for recreation-related uses of public lands? 2931.2 Section 2931.2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE...

  9. 43 CFR 2931.2 - What kinds of permits does BLM issue for recreation-related uses of public lands?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false What kinds of permits does BLM issue for recreation-related uses of public lands? 2931.2 Section 2931.2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE...

  10. Evaluation of structural issues related to isolation of the 100-KE/100-KW discharge chute

    SciTech Connect

    Winkel, B.V.; Hyde, L.L.

    1995-03-10

    The issue of excessive post-seismic leakage in the discharge chute of the K East and K West fuel storage basins was resolved by designing isolation barriers to maintain basin water levels if the discharge chute should drain. This report addresses the structural issues associated with isolation of the discharge chute. The report demonstrates the structural adequacy of the components associated with chute isolation for normal and seismic loading. Associated issues, such as hardware drop accidents and seismic slosh heights are also addressed.

  11. Strategies and issues for managing menopause-related symptoms in diverse populations: ethnic and racial diversity.

    PubMed

    Rice, Valerie Montgomery

    2005-12-19

    Menopause is a naturally occurring "equal opportunity" event that every woman who lives beyond the age of approximately 52 years will experience. During the next 20 years, approximately 3.5 million African American women, 2 million Latinas, and 1 million Asian American women will enter the menopause. How a woman approaches the menopausal transition depends on a number of factors, from educational level to socioeconomic status; health-related factors, including stress; and marital status. Increasingly, the roles of race and ethnicity, as they relate to menopausal symptoms, are being explored. Understanding similarities and differences among women of color in perceptions, attitudes, and expectations surrounding the menopause can help provide culturally appropriate care and promote lifestyles that may decrease symptoms and increase quality of life. For example, minority women are usually the gatekeepers for healthcare for themselves and their families and have a highly developed social support network, often including extended family, a church community, and involvement in sororal or social organizations. In the future, research on menopausal symptoms among women of different racial/ethnic groups should focus on exploring in greater detail the effect of dietary factors and body mass index, additional evaluation of pituitary sensitivity, and use of complementary and alternative medicines in symptom management, with a better understanding of the risks and benefits of such therapies. PMID:16414340

  12. Invariance of molecular charge transport upon changes of extended molecule size and several related issues.

    PubMed

    Bâldea, Ioan

    2016-01-01

    As a sanity test for the theoretical method employed, studies on (steady-state) charge transport through molecular devices usually confine themselves to check whether the method in question satisfies the charge conservation. Another important test of the theory's correctness is to check that the computed current does not depend on the choice of the central region (also referred to as the "extended molecule"). This work addresses this issue and demonstrates that the relevant transport and transport-related properties are indeed invariant upon changing the size of the extended molecule, when the embedded molecule can be described within a general single-particle picture (namely, a second-quantized Hamiltonian bilinear in the creation and annihilation operators). It is also demonstrates that the invariance of nonequilibrium properties is exhibited by the exact results but not by those computed approximately within ubiquitous wide- and flat-band limits (WBL and FBL, respectively). To exemplify the limitations of the latter, the phenomenon of negative differential resistance (NDR) is considered. It is shown that the exactly computed current may exhibit a substantial NDR, while the NDR effect is absent or drastically suppressed within the WBL and FBL approximations. The analysis done in conjunction with the WBLs and FBLs reveals why general studies on nonequilibrium properties require a more elaborate theoretical than studies on linear response properties (e.g., ohmic conductance and thermopower) at zero temperature. Furthermore, examples are presented that demonstrate that treating parts of electrodes adjacent to the embedded molecule and the remaining semi-infinite electrodes at different levels of theory (which is exactly what most NEGF-DFT approaches do) is a procedure that yields spurious structures in nonlinear ranges of current-voltage curves. PMID:27335734

  13. 1.5-μm optical up-conversion: wafer fusion and related issues

    NASA Astrophysics Data System (ADS)

    Ban, Dayan; Luo, Hui; Liu, Hui-Chun; SpringThorpe, Anthony J.; Wasilewski, Zbigniew R.; Bezinger, Andrew; Bogdanov, Alexei; Buchanan, Margaret

    2004-11-01

    Imaging devices working in the near infrared (NIR), especially in the so-called eye-safe range, i.e., around 1.5 mm, have become increasingly important in many military and commercial applications; these include night vision, covert surveillance, range finding and semiconductor wafer inspection. We proposed a new approach in which a wafer-fused optical up-converter, combined with a commercially available charged coupled device (CCD), functions as an infrared camera. The optical up-converter converts incoming infrared light into shorter wavelength radiation that can be efficiently detected by the silicon CCD (cutoff wavelength about 1 mm). An optical up-converter with high efficiency at room-temperature is critical for low cost and large-area infrared imaging applications. A prototype 1.5 mm optical up-converter based on wafer fusion technology has been successfully fabricated. The device consists of an InGaAs/InP pin photodetector and a GaAs/AlGaAs light emitting diode. Experimental results show that the end-to-end up-conversion efficiency is 0.0177 W/W at room-temperature, corresponding to an internal quantum up-conversion efficiency of 76%. In this paper, the design, fabrications and characterization of the optical up-conversion devices is presented. Issues related to device optimization, such as improving internal and external up-conversion efficiency, are addressed. Preliminary results demonstrate the room-temperature up-conversion imaging operation of a pixelated wafer-fused device.

  14. A Qualitative Study of Service Provision for Alcohol Related Health Issues in Mid to Later Life

    PubMed Central

    Haighton, Catherine; Wilson, Graeme; Ling, Jonathan; McCabe, Karen; Crosland, Ann; Kaner, Eileen

    2016-01-01

    Aims Epidemiological surveys over the last 20 years show a steady increase in the amount of alcohol consumed by older age groups. Physiological changes and an increased likelihood of health problems and medication use make older people more likely than younger age groups to suffer negative consequences of alcohol consumption, often at lower levels. However, health services targeting excessive drinking tend to be aimed at younger age groups. The aim of this study was to gain an in-depth understanding of experiences of, and attitudes towards, support for alcohol related health issues in people aged 50 and over. Methods Qualitative interviews (n = 24, 12 male/12 female, ages 51–90 years) and focus groups (n = 27, 6 male/21 female, ages 50–95 years) were carried out with a purposive sample of participants who consumed alcohol or had been dependent. Findings Participants’ alcohol misuse was often covert, isolated and carefully regulated. Participants tended to look first to their General Practitioner for help with alcohol. Detoxification courses had been found effective for dependent participants but only in the short term; rehabilitation facilities were appreciated but seen as difficult to access. Activities, informal groups and drop-in centres were endorsed. It was seen as difficult to secure treatment for alcohol and mental health problems together. Barriers to seeking help included functioning at a high level, concern about losing positive aspects of drinking, perceived stigma, service orientation to younger people, and fatalistic attitudes to help-seeking. Facilitators included concern about risk of fatal illness or pressure from significant people. Conclusion Primary care professionals need training on improving the detection and treatment of alcohol problems among older people. There is also a compelling need to ensure that aftercare is in place to prevent relapse. Strong preferences were expressed for support to be provided by those who had experienced

  15. Invariance of molecular charge transport upon changes of extended molecule size and several related issues

    PubMed Central

    2016-01-01

    Summary As a sanity test for the theoretical method employed, studies on (steady-state) charge transport through molecular devices usually confine themselves to check whether the method in question satisfies the charge conservation. Another important test of the theory’s correctness is to check that the computed current does not depend on the choice of the central region (also referred to as the “extended molecule”). This work addresses this issue and demonstrates that the relevant transport and transport-related properties are indeed invariant upon changing the size of the extended molecule, when the embedded molecule can be described within a general single-particle picture (namely, a second-quantized Hamiltonian bilinear in the creation and annihilation operators). It is also demonstrates that the invariance of nonequilibrium properties is exhibited by the exact results but not by those computed approximately within ubiquitous wide- and flat-band limits (WBL and FBL, respectively). To exemplify the limitations of the latter, the phenomenon of negative differential resistance (NDR) is considered. It is shown that the exactly computed current may exhibit a substantial NDR, while the NDR effect is absent or drastically suppressed within the WBL and FBL approximations. The analysis done in conjunction with the WBLs and FBLs reveals why general studies on nonequilibrium properties require a more elaborate theoretical than studies on linear response properties (e.g., ohmic conductance and thermopower) at zero temperature. Furthermore, examples are presented that demonstrate that treating parts of electrodes adjacent to the embedded molecule and the remaining semi-infinite electrodes at different levels of theory (which is exactly what most NEGF-DFT approaches do) is a procedure that yields spurious structures in nonlinear ranges of current–voltage curves. PMID:27335734

  16. Ethical issues relating to the banking of umbilical cord blood in Mexico

    PubMed Central

    2009-01-01

    Background Umbilical cord banks are a central component, as umbilical cord tissue providers, in both medical treatment and scientific research with stem cells. But, whereas the creation of umbilical cord banks is seen as successful practice, it is perceived as a risky style of play by others. This article examines and discusses the ethical, medical and legal considerations that arise from the operation of umbilical cord banks in Mexico. Discussion A number of experts have stated that the use of umbilical cord goes beyond the mere utilization of human tissues for the purpose of treatment. This tissue is also used in research studies: genetic studies, studies to evaluate the effectiveness of new antibiotics, studies to identify new proteins, etc. Meanwhile, others claim that the law and other norms for the functioning of cord banks are not consistent and are poorly defined. Some of these critics point out that the confidentiality of donor information is handled differently in different places. The fact that private cord banks offer their services as "biological insurance" in order to obtain informed consent by promising the parents that the tissue that will be stored insures the health of their child in the future raises the issue of whether the consent is freely given or given under coercion. Another consideration that must be made in relation to privately owned cord banks has to do with the ownership of the stored umbilical cord. Summary Conflicts between moral principles and economic interests (non-moral principles) cause dilemmas in the clinical practice of umbilical cord blood storage and use especially in privately owned banks. This article presents a reflection and some of the guidelines that must be followed by umbilical cord banks in order to deal with these conflicts. This reflection is based on the fundamental notions of ethics and public health and seeks to be a contribution towards the improvement of umbilical cord banks' performance. PMID:19678958

  17. Modeling and resonance issues of wind farm integration with related facts applications

    NASA Astrophysics Data System (ADS)

    Auddy, Soubhik

    shown that the performance of the TCSC is superior to SVC for damping SSR. These two FACTS devices are primarily employed for achieving other objectives, such as, power transfer improvement and are simultaneously utilized for damping SSR. This thesis also examines for the first time the potential for overvoltages due to ferroresonance and self-excitation while connecting large wind farms to EHV lines. A detailed analysis of the factors influencing self-excitation and ferroresonance has been performed. The impacts of different generator models on the overvoltage issues are examined. Different measures of alleviating these overvoltages are proposed which include line differential protection and wind turbine generator excitation system control. This study has been conducted using EMTDC/PSCAD for an upcoming large wind farm in Ontario. In an effort to validate a doubly fed induction generator (DFIG) model an additional study has been done to validate the DFIG model available in PSS/E from an extensive field validation study of Hydro One Network Inc. Keywords. Power system stability, Transient stability, Inter-area oscillations, Remote Signals, Wide Area Measurement (WAM), Subsynchronous Resonance (SSR), Flexible AC Transmission Systems (FACTS), Static VAR Compensator (SVC), Thyristor Controlled Series Capacitor (TCSC), Wind Farm, Wind Energy Conversion Systems (WECS), Wind Power Systems (WPS), Wind Turbine Generator (WTG), Self-excited induction generator (SEIG), Doubly Fed Induction Generator (DFIG), Ferroresonance, Self-excitation.

  18. Human papillomavirus-related disease in men: not just a women's issue.

    PubMed

    Palefsky, Joel M

    2010-04-01

    The most common cause of mortality related to human papillomavirus (HPV) infection is cervical cancer. However, male HPV infection is also an important concern, both for the disease burden in men and for the risk of transmission to women. HPV is associated with a variety of cancers in men, including anal cancer and a subset of penile and oral cancers. The incidence of anal and oral cancers related to HPV is increasing in the general population and is growing even faster among individuals who are immunocompromised because of human immunodeficiency virus (HIV) infection. Penile HPV infection is very common among heterosexual men and remains high throughout a wide range of ages. Likewise, anal HPV infection and anal intraepithelial neoplasia are very common throughout a wide range of ages in both HIV-negative and HIV-positive men who have sex with men. Other HPV-related diseases of clinical importance in men include condylomata acuminata (genital warts) and recurrent respiratory papillomatosis. The quadrivalent HPV vaccine has been shown to be highly efficacious in the prevention of genital warts in women and precancerous lesions of the cervix, vulva, and vagina. In addition, recent interim data have shown that the quadrivalent HPV vaccine is highly effective in reducing external genital lesions in young men. Although the protective efficacy of HPV vaccination in men has not yet been fully established-pending the outcome of public policy discussions and cost-efficacy studies-there may be a strong rationale for vaccinating boys, similar to girls, at an early age when they have had limited or no prior sexual activity. PMID:20307839

  19. Issues related to setting exemption levels for oil and gas NORM

    SciTech Connect

    Blunt, D. L.; Gooden, D. S.; Smith, K. P.

    1999-11-12

    In the absence of any federal regulations that specifically address the handling and disposal of wastes containing naturally occurring radioactive material (NORM), individual states have taken responsibility for developing their own regulatory programs for NORM. A key issue in developing NORM rules is defining exemption levels--specific levels or concentrations that determine which waste materials are subject to controlled management. In general, states have drawn upon existing standards and guidelines for similar waste types in establishing exemption levels for NORM. Simply adopting these standards may not be appropriate for oil and gas NORM for several reasons. The Interstate Oil and Gas Compact Commission's NORM Subcommittee has summarized the issues involved in setting exemption levels in a report titled ``Naturally Occurring Radioactive Materials (NORM): Issues from the Oil and Gas Point of View''. The committee has also recommended a set of exemption levels for controlled practices and for remediation activities on the basis of the issues discussed.

  20. SOME STATISTICAL ISSUES RELATED TO MULTIPLE LINEAR REGRESSION MODELING OF BEACH BACTERIA CONCENTRATIONS

    EPA Science Inventory

    As a fast and effective technique, the multiple linear regression (MLR) method has been widely used in modeling and prediction of beach bacteria concentrations. Among previous works on this subject, however, several issues were insufficiently or inconsistently addressed. Those is...

  1. Legal and Ethical Issues Related to the Management of Cultural Heritage in Space

    NASA Astrophysics Data System (ADS)

    Walsh, Justin

    in space. The United Nations Outer Space Treaty of 1967 -the primary document governing how nations act in outer space -is now hopelessly out-of-date. There is no mention in the treaty of cultural heritage (the UNESCO convention that concerns international protection of cultural heritage on Earth was not completed until 1970), nor was there any recognition of the role private groups and individuals might play in space exploration. This paper will outline key legal and ethical issues related to cultural heritage management and protection. It will also suggest some ways in which culturally significant sites in space can be protected for future study and even touristic appreciation.

  2. Addition by Subtraction: The Relation Between Dropout Rates and School-Level Academic Achievement

    PubMed Central

    GLENNIE, ELIZABETH; BONNEAU, KARA; VANDELLEN, MICHELLE; DODGE, KENNETH A.

    2013-01-01

    Background/Context Efforts to improve student achievement should increase graduation rates. However, work investigating the effects of student-level accountability has consistently demonstrated that increases in the standards for high school graduation are correlated with increases in dropout rates. The most favored explanation for this finding is that high-stakes testing policies that mandate grade repetition and high school exit exams may be the tipping point for students who are already struggling academically. These extra demands may, in fact, push students out of school. Purpose/Objective/Focus This article examines two hypotheses regarding the relation between school-level accountability and dropout rates. The first posits that improvements in school performance lead to improved success for everyone. If school-level accountability systems improve a school for all students, then the proportion of students performing at grade level increases, and the dropout rate decreases. The second hypothesis posits that schools facing pressure to improve their overall accountability score may pursue this increase at the cost of other student outcomes, including dropout rate. Research Design Our approach focuses on the dynamic relation between school-level academic achievement and dropout rates over time—that is, between one year’s achievement and the subsequent year’s dropout rate, and vice versa. This article employs longitudinal data of records on all students in North Carolina public schools over an 8-year period. Analyses employ fixed-effects models clustering schools and districts within years and controls each year for school size, percentage of students who were free/reduced-price lunch eligible, percentage of students who are ethnic minorities, and locale. Findings/Results This study finds partial evidence that improvements in school-level academic performance will lead to improvements (i.e., decreases) in school-level dropout rates. Schools with improved

  3. Assessment of science-related environmental issues among Venezuelan students, with comparison to United States Student Data

    SciTech Connect

    Campos-Arredondo, O.D.J.

    1985-01-01

    This study is a comparative investigation of the current level of understanding of science-related environmental issues of students in the United States and Venezuela. Major facets of the study include the following aspects. The principal science-related environmental issues included in environmental curriculum programs in the United States and Venezuela were identified from school curriculum-programs, dissertations, environmental studies of the National Association of Environmental Education in the United States, and the Memoria y Cuenta (Memoirs and Accounts) of the ministries of Education and Environment in Venezuela. The National Assessment of Educational Progress (NAEP) test items pertaining to science-related environmental issues administered to representative United States' students in 1981-1982, were subsequently translated and administered to comparable students in Venezuela, in 1984.

  4. Multicultural Issues.

    ERIC Educational Resources Information Center

    Reid, Charrles; Kampfe, Charlene

    This chapter examines issues related to working with diverse populations with addictions. A brief history of multiculturalism and multicultural counseling is presented. Issues particular to the treatment of people with addictions are examined, as well as prevention and assessment issues. Substance abuse issues among people in the gay male and…

  5. Molecular cloning and expression of an additional epidermal growth factor receptor-related gene.

    PubMed Central

    Plowman, G D; Whitney, G S; Neubauer, M G; Green, J M; McDonald, V L; Todaro, G J; Shoyab, M

    1990-01-01

    Epidermal growth factor (EGF), transforming growth factor alpha (TGF-alpha), and amphiregulin are structurally and functionally related growth regulatory proteins. These secreted polypeptides all bind to the 170-kDa cell-surface EGF receptor, activating its intrinsic kinase activity. However, amphiregulin exhibits different activities than EGF and TGF-alpha in a number of biological assays. Amphiregulin only partially competes with EGF for binding EGF receptor, and amphiregulin does not induce anchorage-independent growth of normal rat kidney cells (NRK) in the presence of TGF-beta. Amphiregulin also appears to abrogate the stimulatory effect of TGF-alpha on the growth of several aggressive epithelial carcinomas that overexpress EGF receptor. These findings suggest that amphiregulin may interact with a separate receptor in certain cell types. Here we report the cloning of another member of the human EGF receptor (HER) family of receptor tyrosine kinases, which we have named "HER3/ERRB3." The cDNA was isolated from a human carcinoma cell line, and its 6-kilobase transcript was identified in various human tissues. We have generated peptide-specific antisera that recognizes the 160-kDa HER3 protein when transiently expressed in COS cells. These reagents will allow us to determine whether HER3 binds amphiregulin or other growth regulatory proteins and what role HER3 protein plays in the regulation of cell growth. Images PMID:2164210

  6. Guidance in social and ethical issues related to clinical, diagnostic care and novel therapies for hereditary neuromuscular rare diseases: "translating" the translational.

    PubMed

    McCormack, Pauline; Woods, Simon; Aartsma-Rus, Annemieke; Hagger, Lynn; Herczegfalvi, Agnes; Heslop, Emma; Irwin, Joseph; Kirschner, Janbernd; Moeschen, Patrick; Muntoni, Francesco; Ouillade, Marie-Christine; Rahbek, Jes; Rehmann-Sutter, Christoph; Rouault, Francoise; Sejersen, Thomas; Vroom, Elizabeth; Straub, Volker; Bushby, Kate; Ferlini, Alessandra

    2013-01-01

    Drug trials in children engage with many ethical issues, from drug-related safety concerns to communication with patients and parents, and recruitment and informed consent procedures. This paper addresses the field of neuromuscular disorders where the possibility of genetic, mutation-specific treatments, has added new complexity. Not only must trial design address issues of equity of access, but researchers must also think through the implications of adopting a personalised medicine approach, which requires a precise molecular diagnosis, in addition to other implications of developing orphan drugs. It is against this background of change and complexity that the Project Ethics Council (PEC) was established within the TREAT-NMD EU Network of Excellence. The PEC is a high level advisory group that draws upon the expertise of its interdisciplinary membership which includes clinicians, lawyers, scientists, parents, representatives of patient organisations, social scientists and ethicists. In this paper we describe the establishment and terms of reference of the PEC, give an indication of the range and depth of its work and provide some analysis of the kinds of complex questions encountered. The paper describes how the PEC has responded to substantive ethical issues raised within the TREAT-NMD consortium and how it has provided a wider resource for any concerned parent, patient, or clinician to ask a question of ethical concern. Issues raised range from science related ethical issues, issues related to hereditary neuromuscular diseases and the new therapeutic approaches and questions concerning patients rights in the context of patient registries and bio-banks. We conclude by recommending the PEC as a model for similar research contexts in rare diseases. PMID:23330068

  7. Guidance in Social and Ethical Issues Related to Clinical, Diagnostic Care and Novel Therapies for Hereditary Neuromuscular Rare Diseases: “Translating“ the Translational

    PubMed Central

    McCormack, Pauline; Woods, Simon; Aartsma-Rus, Annemieke; Hagger, Lynn; Herczegfalvi, Agnes; Heslop, Emma; Irwin, Joseph; Kirschner, Janbernd; Moeschen, Patrick; Muntoni, Francesco; Ouillade, Marie-Christine; Rahbek, Jes; Rehmann-Sutter, Christoph; Rouault, Francoise; Sejersen, Thomas; Vroom, Elizabeth; Straub, Volker; Bushby, Kate; Ferlini, Alessandra

    2013-01-01

    Drug trials in children engage with many ethical issues, from drug-related safety concerns to communication with patients and parents, and recruitment and informed consent procedures. This paper addresses the field of neuromuscular disorders where the possibility of genetic, mutation-specific treatments, has added new complexity. Not only must trial design address issues of equity of access, but researchers must also think through the implications of adopting a personalised medicine approach, which requires a precise molecular diagnosis, in addition to other implications of developing orphan drugs. It is against this background of change and complexity that the Project Ethics Council (PEC) was established within the TREAT-NMD EU Network of Excellence. The PEC is a high level advisory group that draws upon the expertise of its interdisciplinary membership which includes clinicians, lawyers, scientists, parents, representatives of patient organisations, social scientists and ethicists. In this paper we describe the establishment and terms of reference of the PEC, give an indication of the range and depth of its work and provide some analysis of the kinds of complex questions encountered. The paper describes how the PEC has responded to substantive ethical issues raised within the TREAT-NMD consortium and how it has provided a wider resource for any concerned parent, patient, or clinician to ask a question of ethical concern. Issues raised range from science related ethical issues, issues related to hereditary neuromuscular diseases and the new therapeutic approaches and questions concerning patients rights in the context of patient registries and bio-banks. We conclude by recommending the PEC as a model for similar research contexts in rare diseases. PMID:23330068

  8. Joint NASA/USAF study on space shuttle orbiter procurement and related issues

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The comprehensive data and analyses are provided for decision on the procurement of additional space shuttle orbiters. The decision required is the number of orbiters needed for the national operational fleet, and how additional orbiters should be funded.

  9. Global climate change policy issues related to the movement of industry from developed to rapidly industrializing countries

    SciTech Connect

    Lesperance, A.M.; Waltemath, L.A.

    1990-10-01

    Global climate change policies adopted by developed countries may encourage industries to move to countries with less restrictive policies. The purpose of this study is to identify policy-driven issues that may result in such a movement. This report (1) summarizes the conclusions of previous studies that have explored the relationship between environmental regulations and industrial movement, (2) identifies and summarizes existing and proposed US global climate change policy options, and (3) discusses issues and topics relating to possible industrial relocation because of the global climate change policy options. It concludes with recommendations for further research. Although federal global climate change policy options are the primary focus of this report, some international and regional efforts addressing this issue are also included. A potential regional industrial migration issue is highlighted. 14 refs., 2 figs., 3 tabs.

  10. Surveillance of Social and Geographic Inequalities in Housing-Related Issues: The Case of the Eastern Townships, Quebec (Canada)

    PubMed Central

    Roy, Mathieu; Généreux, Mélissa; Laverdière, Émélie; Vanasse, Alain

    2014-01-01

    Even though health inequalities are conditioned by many aspects of the environment, much of the existing research focuses on the social environment. This emphasis has the effect to neglect other environmental aspects such as its physical dimension. The physical environment, which is linked to housing conditions, may contribute to the uneven distribution of health. In this study, we examined 19 housing-related issues among a representative sample of 2,000 adults residing in a Quebec (Canada) health region characterized by a mix of rural, semi-rural, and urban areas. The distribution of these issues was examined according to socioeconomic and geographic indicators of social position. Summary measures of inequalities were assessed. Our results showed that the prevalence of nearly all housing-related issues was higher among low-income households compared to more affluent ones. Highly educated individuals showed better housing conditions, whereas different issues tended to cluster in deprived or densely populated areas. To conclude, we observed steep gradients between social class and poor housing conditions. This may explain a substantial part of health inequality on the regional scale. The surveillance of housing-related issues is therefore essential to properly inform and mobilize local stakeholders and to develop interventions that target vulnerable groups on this level. PMID:24806192

  11. Transplant Ethics: Let's Begin the Conversation Anew : A Critical Look at One Institute's Experience with Transplant Related Ethical Issues.

    PubMed

    Shafran, David; Smith, Martin L; Daly, Barbara J; Goldfarb, David

    2016-06-01

    Standardizing consultation processes is increasingly important as clinical ethics consultation (CEC) becomes more utilized in and vital to medical practice. Solid organ transplant represents a relatively nascent field replete with complex ethical issues that, while explored, have not been systematically classified. In this paper, we offer a proposed taxonomy that divides issues of resource allocation from viable solutions to the issue of organ shortage in transplant and then further distinguishes between policy and bedside level issues. We then identify all transplant related ethics consults performed at the Cleveland Clinic (CC) between 2008 and 2013 in order to identify how consultants conceptually framed their consultations by the domains they ascribe to the case. We code the CC domains to those in the Core Competencies for Healthcare Consultation Ethics in order to initiate a broader conversation regarding best practices in these highly complex cases. A discussion of the ethical issues underlying living donor and recipient related consults ensues. Finally, we suggest that the ethical domains prescribed in the Core Competencies provide a strong starting ground for a common intra-disciplinary language in the realm of formal CEC. PMID:26055878

  12. Ectopic gestation: a consideration of new and controversial issues relating to pathogenesis and management.

    PubMed

    Mc Elin, T W; Iffy, L

    1976-01-01

    In this chapter on ectopic gestation are have attempted to elucidate new and controversial issues in this area. In summary, we identify the following items as "nominative imperatives": I. Meticulous review of the classic etiologic concepts of ectopic gestation indicates that these concepts are no longer tenable although certain of them may be operative in specific instances. Review of certain veterinary work, animal experimentation, and pathologic and clinical observations in primates lends support to the hypothesis that failure of the ovum to implant may be related to delayed (post-midcycle) ovulation followed by shortening of the luteal phase with defective endometrial development and by a bleeding episode that simulates menstruation. II. Review of the literature indicates that the woman who has a tubal pregnancy has about a 50 to 60 percent chance of never becoming pregnant again. Among those who do conceive, at least 10 percent, and possibly more, develop another ectopic gestation. Only one-third of the women who have a tubal pregnancy will ever succeed in delivering a healthy child. Obviously this unhappy prognosis is the basis for many of our recommendations for management. The woman who had had a tubal pregnancy should consider the use of mechanical contraception after the midcycle to prevent recurrent ectopic pregnancy. This is obviously a suggestion based on the etiologic theory that we espouse. The prophylactic use of anti-Rh immunoglobulin is necessary in ectopic gestation in Rh-negative gravidas. III. In terms of the relation of ectopic pregnancy to intrauterine devices, the most authoritative statement than can be found is that of Lehfeldt, who states that the IUD is 99.5 percent effective in preventing intrauterine pregnancy, 95 percent effective in preventing tubal ectopic gestation, and is ineffective against ovarian implantation. Nonetheless, the fact that one in 23 IUD pregnancies is ectopic makes consideration of this diagnosis mandatory. IV. In

  13. 78 FR 57505 - World Trade Center Health Program; Addition of Prostate Cancer to the List of WTC-Related Health...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-19

    ...On May 2, 2013, the Administrator of the World Trade Center (WTC) Health Program received a petition (Petition 002) requesting the addition of prostate cancer to the List of WTC-Related Health Conditions (List) covered in the WTC Health Program. In this final rule, the Administrator adds malignant neoplasm of the prostate (prostate cancer) to the List in the WTC Health Program...

  14. Psychological Terms, Logical Positivism, and Realism: Issues Related to Construct Validation.

    ERIC Educational Resources Information Center

    Ellett, Frederick S., Jr.

    1985-01-01

    The standard conception of test validity which makes philosophical assumptions about the nature of scientific inquiry is discussed. The general kinds of questions and issues which psychologists and educators should address in order to develop a complete theory of test validity that is philosophically sound are outlined. (MT)

  15. From Professional Development to Classroom Instruction: Addressing Issues Related to Science Inquiry Discourse

    ERIC Educational Resources Information Center

    Oliveira, Alandeom W.

    2009-01-01

    In this rejoinder, I first provide a more detailed account of the discourse-focused professional development activities facilitated as part of the SMIT'N program, specifically addressing issues raised by van Zee with regard to the institute's overall format, goals and development strategies. Next, I resort to Peter Medawar's metaphorical view of…

  16. Secondary School Students' Interests, Attitudes and Values Concerning School Science Related to Environmental Issues in Finland

    ERIC Educational Resources Information Center

    Uitto, Anna; Juuti, Kalle; Lavonen, Jari; Byman, Reijo; Meisalo, Veijo

    2011-01-01

    This paper explores the relationship between students' interests in environmental issues, attitudes to environmental responsibility and biocentric values in school science education. The factors were investigated within the framework of three moderators: gender, school and residential area of the school. The survey was carried out using the…

  17. The Target Income Hypothesis and Related Issues in Health Manpower Policy.

    ERIC Educational Resources Information Center

    Health Resources Administration (DHEW/PHS), Bethesda, MD. Bureau of Health Manpower.

    The target income hypothesis as applied to health personnel is discussed in seven papers and three commentaries. The hypothesis pertains to the economic behavior of physicians, and it has recently been applied to dentists as well. The issues concern the production/supply of practitioners and the resulting cost for their services. Whether…

  18. The Significance of an Approach to the Teaching of Societal Issues Related to Biotechnology.

    ERIC Educational Resources Information Center

    Conner, Lindsey N.

    This research reports on a constructivist approach that was used in a unit of work with a final year high school biology class. The aim of the intervention was to promote students' awareness and communication of the biological, social, and ethnical issues associated with cancer. Students were encouraged to use an inquiry approach. They were also…

  19. Education of the handicapped child: Status, trend, and issues related to electronic delivery

    NASA Technical Reports Server (NTRS)

    Rothenberg, D.

    1973-01-01

    This study is part of a broader investigation of the role of large-scale educational telecommunications systems. Thus, data are analyzed and trends and issues discussed to provide information useful to the systems designer who wishes to identify and assess the opportunities for large-scale electronic delivery of education for the handicapped.

  20. Using Popular Culture Texts in the Classroom to Interrogate Issues of Gender Transgression Related Bullying

    ERIC Educational Resources Information Center

    Happel-Parkins, Alison; Esposito, Jennifer

    2015-01-01

    This article examines how undergraduate instructors of pre-service educators can address complex issues of sexuality and sexual orientation within the classroom. First, we explain our own backgrounds and positionalities to provide a context for our ensuing ideas and discussions. Second, by reviewing the literature on homophobic bullying, we…

  1. Ethical Issues Relative to Autonomy and Personal Control in Independent and Cognitively Impaired Elders.

    ERIC Educational Resources Information Center

    Rice, Virginia Hill; And Others

    1997-01-01

    Discusses ethical issues surrounding health care for independent elders, those in long-term care, and those with cognitive impairments, as well as death, dying, euthanasia, and assisted suicide. Suggests that nurses should focus on older adults' choice, autonomy, and personal control. (SK)

  2. Ethical Issues Relating to Teaching via an Interactive Two-Way Television System (ITV).

    ERIC Educational Resources Information Center

    Thoms, Karen Jarrett

    The information age has introduced new methods of delivering educational materials to students. One method is two-way interactive television (ITV). As more schools utilize ITV, for distance education and other educational purposes, certain administrative, legal, and ethical issues need to be addressed. This paper focuses on human and ethical…

  3. Educational Finance. Briefing Paper: Texas Public School Finance and Related Issues.

    ERIC Educational Resources Information Center

    Clark, Catherine P.; England, Claire

    This document explores various issues that affect Texas public school finance. It opens with an overview of the Texas public school system, which comprises 1,043 independent school districts, with an average of 6.4 campuses per district. The federal role in financing schools is examined, along with education finance and the state budget. Four…

  4. Turkish Preservice Teachers' Perceptions of Children's Picture Books Reflecting LGBT-Related Issues

    ERIC Educational Resources Information Center

    Dedeoglu, Hakan; Ulusoy, Mustafa; Lamme, Linda L.

    2012-01-01

    This research study focuses on Turkish preservice teachers' perceptions of children's picture books containing lesbian, gay, bisexual, and transgender issues to lend support to encouraging diversity in teacher education programs and elementary school classrooms. The authors proposed that reading, listening, and responding to diverse children's…

  5. Implementation of the 1993 Pennsylvania Educational Reform: Issues Related to Strategic Planning.

    ERIC Educational Resources Information Center

    Pliska, Ann-Maureen

    The purpose of this study was to investigate the problems and issues that emerged as school districts in Pennsylvania tried to implement a strategic planning mandate at the local level. In June 1993, revisions to the Pennsylvania school code changed requirements for graduation from time spent in the classroom to the mastery of 53 state-designated…

  6. Public Higher Education Funding, Budget Drivers, and Related Issues: The State Community College Director Perspective

    ERIC Educational Resources Information Center

    Katsinas, Stephen G.; D'Amico, Mark M.; Friedel, Janice N.

    2014-01-01

    This article presents results from the 2012 National Survey of Access and Finance Issues conducted by the National Council of State Directors of Community Colleges (NCSDCC), an affiliated council of the American Association of Community Colleges, and includes a comparison of survey results from previous years dating back to 2003, with the…

  7. Teachers' Controversial Issue Decisions Related to Race, Gender, and Religion during the 2008 Presidential Election

    ERIC Educational Resources Information Center

    Journell, Wayne

    2011-01-01

    Using the 2008 Presidential Election as a case of curricular controversy, the author describes how six high school government teachers responded to the racial, gender, and religious diversity included on the presidential tickets of the two major political parties. Teachers had to decide whether the issue of Americans challenging the tradition of…

  8. Issues Related to the Use of Z39.50 To Emulate a Centralized Union Catalogue.

    ERIC Educational Resources Information Center

    Lunau, Carrol; Turner, Fay

    The virtual Canadian union catalog (vCuc) project is a project among Canadian libraries to use Z39.50 (an information protocol standard) for searching distributed individual library catalogs and union catalogs. This paper summarizes the major technical, vendor, bibliographic data, and administrative issues that must be resolved before the…

  9. COSTS AND ISSUES RELATED TO REMEDIATION OF PETROLEUM-CONTAMINATED SITES (NEW ORLEANS, LA)

    EPA Science Inventory

    The remediation costs required at sites contaminated with petroleum-derived compounds remains a relevant issue because of the large number of existing underground storage tanks the United States and the presence of benzene, MTBE, and TBA in some drinking water supplies. Cost inf...

  10. COSTS AND ISSUES RELATED TO REMEDIATION OF PETROLEUM-CONTAMINATED SITES

    EPA Science Inventory

    The remediation costs required at sites contaminated with petroleum-derived compounds remains a relevant issue because of the large number of existing underground storage tanks the United States and the presence of benzene, MTBE, and TBA in some drinking water supplies. Cost inf...

  11. Issues Related to the Construction of a Purpose-Built Domain-Specific Word Corpus

    ERIC Educational Resources Information Center

    Thomas, Lisa; Pfister, H. Peter; Peterson, Peter

    2004-01-01

    There is growing interest in the use of semantic collections in order to identify and analyse domain knowledge. This paper describes some technical issues to consider when contemplating research which incorporates small-to-medium domain-specific word sets. The purpose of the corpus construction described was to provide an external word collection…

  12. Asbestos-related lung cancer and malignant mesothelioma of the pleura: selected current issues.

    PubMed

    Markowitz, Steven

    2015-06-01

    Asbestos-related diseases persist, because millions of workers have had prior exposure and many industrializing countries continue to use asbestos. Globally, an estimated 107,000 people die annually from lung cancer, malignant mesothelioma, and asbestosis due to occupational asbestos exposure. Malignant mesothelioma and lung cancer are caused by all major types of asbestos. Asbestos causes more lung cancer deaths than malignant mesothelioma of the pleura; most cases of the latter are due to asbestos exposure. The cancer risk increases with cumulative asbestos exposure, with increased risk even at low levels of exposure to asbestos. Based on empirical studies, an estimated cumulative occupational exposure to asbestos of 1 fiber/mL-year substantially raises malignant mesothelioma risk. No safe threshold for asbestos exposure has been established for lung cancer and mesothelioma. The validity of fiber-type risk assessments depends critically on the quality of exposure assessments, which vary considerably, leading to a high degree of uncertainty. Asbestos exposure without asbestosis and smoking increases the risk of lung cancer. The joint effect of asbestos and smoking is supra-additive, which may depend in part on the presence of asbestosis. Asbestos workers who cease smoking experience a dramatic drop in lung cancer risk, which approaches that of nonsmokers after 30 years. Studies to date show that longer, thinner fibers have a stronger association with lung cancer than shorter, less thin fibers, but the latter nonetheless also show an association with lung cancer and mesothelioma. Low-dose chest computed tomographic scanning offers an unprecedented opportunity to detect early-stage lung cancers in asbestos-exposed workers. PMID:26024342

  13. [White House Conference on Aging, 1981: Health-Related and Medical Care Issues of the Elderly. Eighteen Reports.

    ERIC Educational Resources Information Center

    White House Conference on Aging, Washington, DC.

    This document contains the 18 papers on health-related and medical care issues of the elderly that were presented at the 1981 White House Conference on Aging. The materials focus on the following topics: physical mobility, death, heart disease, nutrition, injury, senile dementia, post-menopausaul women, gerontological nursing, learning and memory,…

  14. Methodological Issues Related to the Use of P Less than 0.05 in Health Behavior Research

    ERIC Educational Resources Information Center

    Duryea, Elias; Graner, Stephen P.; Becker, Jeremy

    2009-01-01

    This paper reviews methodological issues related to the use of P less than 0.05 in health behavior research and suggests how application and presentation of statistical significance may be improved. Assessment of sample size and P less than 0.05, the file drawer problem, the Law of Large Numbers and the statistical significance arguments in…

  15. EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments (External Review Draft)

    EPA Science Inventory

  1. SPECIAL ISSUE OF THE JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION ON THE PARTICULATE MATTER SUPERSITES PROGRAM AND RELATED STUDIES

    EPA Science Inventory

    This article is the preface or editors note to the dedicated issue of the Journal of the Air & Waste Management Association for a selection of scientific papers from the specialty conference entitled, "Particulate Matter Supersites Program and Related Studies," that was...

  2. Report of the Committee to Examine Issues Related to the Use of the Norm Referenced Model for Title I Evaluation.

    ERIC Educational Resources Information Center

    Hansen, Joe B., Comp.

    This report documents the activities of the technical committee formed to examine issues related to the norm-referenced model (RMC Model A) for evaluation of Elementary and Secondary Education Act Title I programs. Background information is provided on the committee's activities, purpose, and meetings; and the members are listed. The reports of…

  3. 75 FR 76705 - Joint Public Roundtable on Issues Related to Capital and Margin Requirements for Swaps and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-09

    ... COMMISSION SECURITIES AND EXCHANGE COMMISSION Joint Public Roundtable on Issues Related to Capital and Margin... Protection Act (the ``Act'') that require the Agencies ] to adopt rules for the capital and margin... published at http://www.cftc.gov/LawRegulation/DoddFrankAct/OTC_5_CapMargin.html . The roundtable...

  4. Issues Relating to Women's Immigration Status. Tierra de Oportunidad Module 8. LAES: Latino Adult Education Services Project.

    ERIC Educational Resources Information Center

    Kissam, Ed; Dorsey, Holda

    This module, which may be used as the basis for a workshop or as a special topic unit in adult basic education or English-as-a-Second-Language (ESL) courses, focuses on issues related to women's immigration status. The following items are included: module overview; list of basic, thinking, interpersonal, information utilization, and other skills…

  5. Analysis of Environmental Issues Related to Small-Scale Hydroelectric Development IV: Fish Mortality Resulting From Turbine Passage

    SciTech Connect

    Turbak, Susan C.; Reichle, Donna R.; Shriner, Carole R.

    1981-01-01

    The purpose of this report is to provide summary information for use by potential developers and regulators of small-scale hydroelectric projects (defined as existing dams that can be retrofitted to a total site capacity of ≤30 MW), where turbine-related mortality of fish is a potential issue affecting site-specific development. Mitigation techniques for turbine-related mortality are not covered in this report.

  6. Anticipating issues related to increasing preimplantation genetic diagnosis use: a research agenda.

    PubMed

    Klitzman, Robert; Appelbaum, Paul S; Chung, Wendy; Sauer, Mark

    2008-01-01

    Increasing use of preimplantation genetic diagnosis (PGD) poses numerous clinical, social, psychological, ethical, legal and policy dilemmas, many of which have received little attention. Patients and providers are now considering and using PGD for a widening array of genetic disorders, and patients may increasingly seek 'designer babies.' In the USA, although governmental oversight policies have been discussed, few specific guidelines exist. Hence, increasingly, patients and providers will face challenging ethical and policy questions of when and for whom to use PGD, and how it should be financed. These issues should be better clarified and addressed through collection of data concerning the current use of PGD in the USA, including factors involved in decision making about PGD use, as well as the education of the various communities that are, and should be, involved in its implementation. Improved understanding of these issues will ultimately enhance the development and implementation of future clinical guidelines and policies. PMID:18644221

  7. The effect of plant aging on equipment qualification and human performance issues related to license renewal

    SciTech Connect

    Gunther, W.E.; Higgins, J.C.; Aggarwal, S.K.

    1991-12-31

    The aging of nuclear power plants is one of the most important issues facing the nuclear industry worldwide. Aging encompasses as forms of degradation to nuclear power plant components, systems, and structures that result from exposure to environmental conditions or from operational stresses. Both the degradation from aging and actions taken to address the aging, such as increased maintenance and testing, can significantly impact human performance in the plant. Research into the causes and effects of aging as obtained through the assessment of operating experience and testing have raised questions regarding the adequacy of existing industry standards for addressing the concerns raised by this research. This paper discusses these issues, with particular emphasis in the area of equipment qualification and human performance.

  8. The effect of plant aging on equipment qualification and human performance issues related to license renewal

    SciTech Connect

    Gunther, W.E.; Higgins, J.C. ); Aggarwal, S.K. )

    1991-01-01

    The aging of nuclear power plants is one of the most important issues facing the nuclear industry worldwide. Aging encompasses as forms of degradation to nuclear power plant components, systems, and structures that result from exposure to environmental conditions or from operational stresses. Both the degradation from aging and actions taken to address the aging, such as increased maintenance and testing, can significantly impact human performance in the plant. Research into the causes and effects of aging as obtained through the assessment of operating experience and testing have raised questions regarding the adequacy of existing industry standards for addressing the concerns raised by this research. This paper discusses these issues, with particular emphasis in the area of equipment qualification and human performance.

  9. Environmental health and hazardous waste issues related to the U.S.-Mexico border.

    PubMed Central

    Carter, D E; Peña, C; Varady, R; Suk, W A

    1996-01-01

    Environmental health and environmental quality issues along the U.S.-Mexico border have been of concern for several years. The enactment of the North American Free Trade Agreement and the presence of the maquiladoras (foreign-owned industries using imported raw materials) have intensified those concerns recently. Efforts to assess these issues are complicated by the fact that many of the issues affecting the border region are within federal jurisdiction, but the problems are regional and local in nature. Thus, state and local governments become involved with public concerns about real and potential problems. One major problem is that environmental health data from this region are lacking, particularly from Mexico. Some new agencies such as the Border Environment Cooperation Commission, the United States-Mexico Border Health Commission, and the North American Commission on Environmental Cooperation have joined several existing agencies at the federal and state level to address environmental quality and health. Several studies have been initiated to determine air and water quality, but little is being done in the areas of hazardous waste and health assessment. Several problems are anticipated in the generation of such data, such as its format and accessibility. Data gaps and research needs are discussed. PMID:8793340

  10. Environmental health and hazardous waste issues related to the U.S.-Mexico border.

    PubMed

    Carter, D E; Peña, C; Varady, R; Suk, W A

    1996-06-01

    Environmental health and environmental quality issues along the U.S.-Mexico border have been of concern for several years. The enactment of the North American Free Trade Agreement and the presence of the maquiladoras (foreign-owned industries using imported raw materials) have intensified those concerns recently. Efforts to assess these issues are complicated by the fact that many of the issues affecting the border region are within federal jurisdiction, but the problems are regional and local in nature. Thus, state and local governments become involved with public concerns about real and potential problems. One major problem is that environmental health data from this region are lacking, particularly from Mexico. Some new agencies such as the Border Environment Cooperation Commission, the United States-Mexico Border Health Commission, and the North American Commission on Environmental Cooperation have joined several existing agencies at the federal and state level to address environmental quality and health. Several studies have been initiated to determine air and water quality, but little is being done in the areas of hazardous waste and health assessment. Several problems are anticipated in the generation of such data, such as its format and accessibility. Data gaps and research needs are discussed. PMID:8793340

  11. Issues of scale, location and geologic terrain related to Salt Lake City and Baltimore-Washington metropolitan areas

    USGS Publications Warehouse

    Cleaves, E.T.; Godfrey, A.E.

    2004-01-01

    Planning and development of expanding metropolitan regions require consideration of earth science issues related to issues involving scale, space (location), geologic terrain and physiographic units, and information transfer. This paper explores these matters with examples from the Salt Lake City, Utah area and Mid-Atlantic region of Baltimore-Washington that include water supply and natural hazards (earthquakes, landslides, and sinkholes.) Information transfer methods using physiographic units at national, regional, local and site scales serve to communicate relevant geologic constraint and natural resource information.

  12. U.S. Public Relations from an International Perspective: Curricular Issues and Objectives.

    ERIC Educational Resources Information Center

    Pratt, Cornelius B.; Ogbondah, Chris W.

    This paper establishes a rationale for international public relations courses in the curricula of university public relations education in the U.S. and outlines the content of such courses. Disagreements between practitioners and educators on a blueprint for public relations education are documented. Developments pointing to a crucial need for…

  13. Contamination and changes of food factors during processing with modeling applications-safety related issues

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Chemical and microbiological contamination of food during processing and preservation can result in foodborne illness outbreaks and food poisoning. Chemical contaminations can occur through exposure of foods to illegal additives, pesticides and fertilizer residues, toxic compounds formed by microbes...

  14. 78 FR 39670 - World Trade Center Health Program; Addition of Prostate Cancer to the List of WTC-Related Health...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-02

    ...On May 2, 2013, the Administrator of the World Trade Center (WTC) Health Program received a petition (Petition 002) requesting the addition of prostate cancer to the List of WTC-Related Health Conditions (List) covered in the WTC Health Program. The Administrator has determined to publish a proposed rule adding malignant neoplasm of the prostate (prostate cancer) to the List in the WTC Health......

  15. QA/QC Issues Related to Data From Volunteer Citizen Scientist Networks

    NASA Astrophysics Data System (ADS)

    Woodard, G. C.; Crimmins, M.; Vazquez, R.; Rupprecht, C.

    2007-12-01

    Earth science researchers increasingly are using field data gathered by volunteer citizen scientists, particularly where there is a need for dense or far-flung networks of instruments, or qualitative observations of environmental conditions (e.g., drought-caused plant stress, bird migration, spring ice break-up). Precipitation monitoring is a popular form of citizen science, with hundreds of local networks, and two regional networks - CoCoRaHS with observers in over 20 states, and RainLog, with over 1,200 observers in the Southwestern U.S. Dense networks of rain gages are especially valuable for capturing localized, convective storm events, with the data used for multiple purposes, including research, flood early warning, drought monitoring, and weather reporting. Researchers may be hesitant to use data collected by citizen scientists because of Quality Assurance/Quality Control issues associated with networks of volunteers. Gages vary in precision and accuracy, and citizen scientists have different levels of skill and experience. Backyard gages are not always ideally sited with respect to buildings and trees. Data entry issues include delays in reporting and input errors. Missing data are not only more prevalent than for official gages, the missing data are non-random. Spatial patterns of volunteers' gages reflect development patterns and socio-demographic factors, resulting in clusters and voids in gage distribution. Current interpolation methodologies do not handle these gage patterns well. RainLog is systematically quantifying these QA/QC issues, and where possible, developing procedures to mitigate them. Citizen scientists are kept informed and engaged and informed through a variety of web-based data visualization approaches. Automated monthly data reviews glean missing data and offer an opportunity to check outlier values. Various statistical approaches are used to estimate accuracy and precision for each gage. Finally, we are developing and implementing more

  16. Sudden death in advanced abdominal pregnancy: a case report and discussion of the related medicolegal issues.

    PubMed

    Pradhan, M; Sreenivas, M; Singh, Bajrang; Behera, C; Dikshit, P C

    2013-04-01

    We report sudden unexpected death in a 35-year-old woman with pregnancy of seven months duration. There was an allegation by the parents of the woman that she was subjected to an assault prior to death. Autopsy examination showed an abdominal pregnancy with a dead fetus, ruptured gestational sac, massive haemorrhage and secondary placental attachment. During her antenatal check-ups, she had persistently complained of abdominal pain and loose stools, but the diagnosis of abdominal pregnancy was missed clinically and on ultrasound scan. In this paper we discuss the diagnostic difficulties and medicolegal issues in such cases. PMID:23362236

  17. PBL triggers in relation to students’ generated learning issues and predetermined faculty objectives: Study in a Malaysian public university

    PubMed Central

    Ruslai, Nurul Hidayati; Salam, Abdus

    2016-01-01

    Objectives: Foundational elements of problem based learning (PBL) are triggers, tutors and students. Ineffective triggers are important issues for students’ inability to generate appropriate learning issues. The objective of this study was to evaluate PBL triggers and to determine similarities of students’ generated learning issues with predetermined faculty objectives. Methods: It was a retrospective study conducted in 2014 analyzing all 24 PBL-triggers used at Centre for Foundation Studies, International Islamic University Malaysia, in four semesters during two consecutive years 2011 and 2012. Triggers were used as textual and illustration format equally in each semester. Total 16 PBL-triggers with highest and lowest achieving similarities of learning issues with predetermined faculty objectives were selected equally from each semester and format. The trigger quality and learning issues related to predetermine faculty objectives were analyzed and presented as mean and percent distribution. Results: Mean similarities score of students’ generated learning issues were 3.4 over 5 predetermined faculty objectives which was 68%, varied from 58% to 79%. More than 70% similarities were generated from five textual and four illustrated triggers, while <70% similarities observed from four illustrated and three textual triggers. Conclusion: Whatever the trigger formats in PBL, it is the designing considering influential variables that influence higher outcomes. Triggers should have planned clues that lead students to generate issues correlate with faculty objectives. Educational institution should emphasize on training needs of faculty at regular interval to develop and re-in force teachers’ skills in trigger design, thereby to promote a sustainable educational and organizational development. PMID:27182232

  18. Comparison of environmental issues related to development of small hydropower resources at new versus existing sites

    SciTech Connect

    Loar, J. M.; Hildebrand, S. G.

    1980-01-01

    Many of the ecological issues associated with the development of small hydropower resources are similar at both new (undeveloped) sites and those with existing dams that will be retrofitted for hydroelectric generation. Issues that could occur with both types of development are: (1) blockage of fish migration routes; (2) water level fluctuations; (3) instream flows, (4) water quality; (5) dredging and dredged material disposal; and (6) threatened or endangered species. However, new site development projects require the alteration of existing aquatic and terrestrial ecosystems that will be, in most cases, significantly greater than the environmental changes associated with the retrofitting of existing dams. Although project design and operation are important factors controlling the nature and magnitude of the environmental impacts of small hydropower resource development, the mitigation of adverse impacts (and the optimization of beneficial effects) is dependent, in large measure, on our ability to accurately predict physical, chemical, and biological changes. Predicting the impacts of new impoundments may be considerably more difficult than predicting the impacts that might occur if an existing dam/impoundment system is developed. A comparative approach at the ecosystem level can provide valuable insights into the structure and function of reservoir systems and significantly increase our predictive capability.

  19. Issues related to prediction of residual stresses in titanium alloy matrix composites

    SciTech Connect

    Rangaswamy, P.; Jayaraman, N.

    1995-01-01

    Recently, a detailed study of residual stresses on the as-processed SCS-6/Ti-24Al-11Nb [0]{sub 8} composite, and SCS-6/Beta-21S composites in unidirectional [0]{sub 4}, cross-ply [0/90]s, and quasi-isotropic [0/{+-}45/90]s lay-ups has been completed. In this study, residual stresses have been measured using x-ray diffraction (Sin{sup 2}{Psi}) technique. We have shown that the use of conventional unit cell models consisting of a quarter fiber surrounded by the matrix material to predict residual stresses for verification of experimental results is inadequate. Such models have successfully predicted the stresses at the fiber-matrix interface. However, experimental work to measure residual stresses have always been on surfaces far away from the interface region. In this paper, the approach taken in extending the conventional unit cell model to the concept of multi-fiber models to predict average stresses are presented. In this process, several modeling issues have been identified. These issues are (i) use of conventional unit models for prediction of average surface residual stresses, (ii) effect of orientation of the sub-surface plies on the residual stresses in the surface ply, (iii) residual stresses in the interior plies, and (iv) constituent material properties.

  20. Measurement issues related to data collection on the World Wide Web.

    PubMed

    Strickland, Ora L; Moloney, Margaret F; Dietrich, Alexa S; Myerburg, Stuart; Cotsonis, George A; Johnson, Robert V

    2003-01-01

    As the World Wide Web has become more prominent as a mode of communication, it has opened up new possibilities for research data collection. This article identifies measurement issues that occur with Internet data collection that are relevant to qualitative and quantitative research approaches as they occurred in a triangulated Internet study of perimenopausal women with migraine headaches. Issues associated with quantitative data collection over the Internet include (a) selecting and designing Internet data collection protocols that adequately address study aims while also taking advantage of the Internet, (b) ensuring the reliability and validity of Internet data collected, (c) adapting quantitative paper-and-pencil data collection protocols for the Internet, (d) making Internet data collection practical for respondents and researchers, and (e) ensuring the quality of quantitative data collected. Qualitative data collection over the Internet needs to remain true to the philosophical stance of the qualitative approach selected. Researcher expertise in qualitative data collection must be combined with expertise in computer technology and information services if data are to be of ultimate quality The advantages and limitations of collecting qualitative data in real time or at a later time are explored, as well as approaches to enhance qualitative data collection over the Internet. It was concluded that like any research approach or method, Internet data collection requires considerable creativity, expertise, and planning to take advantage of the technology for the collection of reliable and valid research data. PMID:14674574

  1. Relations between Parenting Style and Children's Play Behavior. Issues in Education.

    ERIC Educational Resources Information Center

    Clawson, Mellisa A.; Robila, Mihaela

    2001-01-01

    Studied Baumrind's approach to parenting style to examine the relations between parenting style and preschool children's social competence manifested through peer play. Found that mothers' and fathers' parenting style is related to children's play with peers, with an authoritative parenting style correlating to more complex levels of play. (SD)

  2. Kinship Foster Care: An Overview of Research Findings and Policy-Related Issues.

    ERIC Educational Resources Information Center

    Clark, Jennifer

    During the past few years, there has been a notable increase in the number of children in foster care, with foster care that is provided by relatives accounting for a substantial part of the increase. At the same time, there has been a shift in thinking in the field of child welfare, from viewing placement with a relative as a last resort to…

  3. Continuing professional education: Status, trends, and issues related to electronic delivery

    NASA Technical Reports Server (NTRS)

    Rothenberg, D.

    1975-01-01

    Four professional groups, teachers, doctors, lawyers, and engineers were examined to determine if they constitute a potential market for continuing professional education via large scale electronic technology. Data were collected in view of social and economic forces, such as mandatory periodic relicensure, additional course requirements for certification, or the economic health of supporting industries.

  4. Technical and policy issues related to semantically and spatially incompatible geodata

    SciTech Connect

    Bespalko, S.J.; Ganter, J.H.; Meter, M.D. Van

    1995-07-01

    Both the Intelligent Transportation Systems (ITS) and National Information Infrastructure (NU) efforts have ambitious goals that are expected to improve the fundamental infrastructure, commerce, and society of the United States. Achieving these goals will require rapid development and deployment of information compatibility methods through technical and institutional standards. These standards will have to be scaleable and flexible to support new, and as-yet-undiscovered, data. Yet they will also need to accommodate our valuable data reserves. The area of geospatial data, and thus the creation of a National Spatial Data Infrastructure (NSDI), is particularly challenging due to the profoundly different forms, evolutionary histories, and meanings attached to spatial data. We discuss technical issues resulting from the different natures and inaccuracy of existing geodata, and areas where federal policy could lead the way to greater compatibility.

  5. Some critical issues and concerns related to research advances on toxicology of chemical mixtures.

    PubMed Central

    Yang, R S

    1998-01-01

    This paper addresses some of the issues and concerns on research advances on the toxicology of chemical mixtures. Emphases will be selectively given to the following questions and answers: Can mechanistic studies be conducted on chemical mixtures? The fact that any studies, including mechanistic studies, of single chemicals are really the study of the parent chemical plus its metabolites underscores the relevance of mechanistic studies on chemical mixtures. Can predictions be made on the health effects of chemical mixtures? Some successes are already evident in the literature on simpler chemical mixtures. For more complex mixtures, it is possible and we propose an approach here. What can we learn from other disciplines (the importance of interdisciplinary collaboration)? Two aspects, the knowledge and methodologies available in clinical pharmacology and the latest advances in structure-oriented lumping in chemical engineering, are discussed in detail. Unrepeatable results: The possibility of magnification of biologic variability because of low-level exposures to chemical mixtures is suggested with special reference to some known examples, including the controversial study on synergistic interactions of endocrine disruptors. Is the driving force for scientific investigations on chemical mixtures the legislative and regulatory atmosphere? Two laws with chemical mixtures specifically in the language are quoted and discussed. Their implications regarding research funding and activities are described. What are the pitfalls of applying for research funding on investigating chemical mixtures? The dilemma at least one investigator faces in pursuing research funding is elaborated. The questions and issues listed above are not all inclusive, but they represent some of the aspects that need to be brought into the open in the scientific community for discussion and/or debate. Thus, the primary objective of this paper is to provide some momentum for the beginning of a fruitful

  6. Field issues related to effectiveness of insecticide-treated nets in Tanzania.

    PubMed

    Erlanger, T E; Enayati, A A; Hemingway, J; Mshinda, H; Tami, A; Lengeler, C

    2004-06-01

    Insecticide-treated nets (ITNs) impregnated with pyrethroid insecticides have become one of the most promising interventions to prevent malaria in highly endemic areas. Despite the large body of experience documenting their health impact and the best way to distribute them, some key practical issues remain unresolved. For example, the duration of effective life of a net under field conditions is unknown. The most important factor affecting net effectiveness is the issue of regular re-treatment with insecticide. Washing is also an important determinant of insecticide longevity in the field. Trials were undertaken to provide some essential field information on ITNs within the site of an extended ITN programme in the Morogoro region of Tanzania. It was found that 45% of all nets were in bad condition (defined as more than seven large holes). It is concluded that an effective 'life' for polyester nets is 2-3 years. Further, two-thirds of the 20% of nets that were reported as having been re-treated within the last 12 months had less than 5 mg/m(2) of insecticide. According to the World Health Organization this is insufficient to be effective. People reported that they washed their nets four to seven times per year, usually with soap. Observations showed that such washing does not harm the nets and that the wash-water was unlikely to have an impact on the environment. Finally, bioassays were carried out with Anopheles gambiae on polyester netting with 0.5, 2, 5, 10 and 30 mg/m(2) of deltamethrin, alphacypermethrin and lambdacyhalothrin to assess the effectiveness of pyrethroids. The results confirmed that even with low insecticide concentrations, nets can still provide partial protection. PMID:15189240

  7. Space Station Engineering Design Issues

    NASA Technical Reports Server (NTRS)

    Mcruer, Duane T.; Boehm, Barry W.; Debra, Daniel B.; Green, C. Cordell; Henry, Richard C.; Maycock, Paul D.; Mcelroy, John H.; Pierce, Chester M.; Stafford, Thomas P.; Young, Laurence R.

    1989-01-01

    Space Station Freedom topics addressed include: general design issues; issues related to utilization and operations; issues related to systems requirements and design; and management issues relevant to design.

  8. Evaluation of health-related quality-of-life measures in oncology drug product applications: issues and concerns.

    PubMed

    Sridhara, Rajeshwari; Chen, Gang; Chi, George Y H; Griebel, Donna J

    2004-02-01

    Health-related quality-of-life outcomes as reported by patients are valuable data and ideally should be critical to evaluating clinical benefit. The unblinded or open-label designs commonly adapted in oncology trials have the potential to introduce selection bias, reporting bias, and analyses bias. In this paper, issues surrounding use of patient reported outcomes to evaluate oncology drug products, including definition of hypothesis, study design, analysis, and interpretation of patient reported outcome data, are reported. PMID:15027498

  9. Responding to the coal-related environmental issues challenging the People`s Republic of China

    SciTech Connect

    Wang, X.

    1998-12-31

    China faces the world`s largest coal-related environmental problems. The Chinese government is giving increased attention to coal-related environmental problems through legislation and specific restrictions on coal use in some areas. This paper reviews the seriousness of coal-related pollution at the household, industry, and power sector levels, and suggests a strategy to reduce the growth rate in coal-related pollution over the next two decades. The most vigorous action will be to reduce local pollution which has the most serious public health impacts. China will probably eventually participate in international agreements to reduce the rate of growth in greenhouse gas emissions. This might provide an important opportunity for the transfer of advanced coal technologies from the US to China.

  10. Some issues in the simulation of two-phase flows: The relative velocity

    NASA Astrophysics Data System (ADS)

    Gräbel, J.; Hensel, S.; Ueberholz, P.; Zeidan, D.; Farber, P.

    2016-06-01

    In this paper we compare numerical approximations for solving the Riemann problem for a hyperbolic two-phase flow model in two-dimensional space. The model is based on mixture parameters of state where the relative velocity between the two-phase systems is taken into account. This relative velocity appears as a main discontinuous flow variable through the complete wave structure and cannot be recovered correctly by some numerical techniques when simulating the associated Riemann problem. Simulations are validated by comparing the results of the numerical calculation qualitatively with OpenFOAM software. Simulations also indicate that OpenFOAM is unable to resolve the relative velocity associated with the Riemann problem.

  11. Accelerator-based conversion (ABC) of weapons plutonium: Plant layout study and related design issues

    SciTech Connect

    Cowell, B.S.; Fontana, M.H.; Krakowski, R.A.; Beard, C.A.; Buksa, J.J.; Davidson, J.W.; Sailor, W.C.; Williamson, M.A.

    1995-04-01

    In preparation for and in support of a detailed R and D Plan for the Accelerator-Based Conversion (ABC) of weapons plutonium, an ABC Plant Layout Study was conducted at the level of a pre-conceptual engineering design. The plant layout is based on an adaptation of the Molten-Salt Breeder Reactor (MSBR) detailed conceptual design that was completed in the early 1070s. Although the ABC Plant Layout Study included the Accelerator Equipment as an essential element, the engineering assessment focused primarily on the Target; Primary System (blanket and all systems containing plutonium-bearing fuel salt); the Heat-Removal System (secondary-coolant-salt and supercritical-steam systems); Chemical Processing; Operation and Maintenance; Containment and Safety; and Instrumentation and Control systems. Although constrained primarily to a reflection of an accelerator-driven (subcritical) variant of MSBR system, unique features and added flexibilities of the ABC suggest improved or alternative approaches to each of the above-listed subsystems; these, along with the key technical issues in need of resolution through a detailed R&D plan for ABC are described on the bases of the ``strawman`` or ``point-of-departure`` plant layout that resulted from this study.

  12. Information and issues related to the quantification of environmental externalities for new powerplants

    SciTech Connect

    Lee, A.D.; Callaway, J.M.; Glantz, C.S.; Baechler, M.C.; Foley, L.O.

    1990-10-01

    This report provides background information for the Bonneville Power Administration (Bonneville) in its efforts to quantify the environmental externalities associated with new electricity resources. A more detailed companion document has been provided to Bonneville for internal use. This report defines what is meant by externalities, particularly in the context of electricity resources. It outlines the economics issues associated with assigning an economic value, such as cents per kilowatt hour, to the residual environmental impacts of electricity powerplants. It examines two generic theoretical approaches for estimating such values and discusses their advantages and disadvantages. The report also addresses the need to include relevant stages in the fuel cycle in estimating the costs of externalities. The fuel-cycle concept is defined and its importance is discussed. The approaches used by several states to quantify externalities are described. A review of the valuation efforts of various states and utilities indicates that three states have actually developed methodologies for assigning economic values to externalities. Information that Bonneville may need to request from resource developers to quantify externalities is discussed, and an appendix presents suggested forms for obtaining the required information. Summary information also is presented on models for analyzing the dispersion of powerplant plumes for the purpose of estimating environmental externality costs. 34 refs., 1 fig., 4 tabs.

  13. Background issues relating to the proposed Mass Literacy Campaign in Nigeria

    NASA Astrophysics Data System (ADS)

    Akinde, Charles O.; Omolewa, Michael

    1982-03-01

    Literacy education in Nigerian history finds its roots in the efforts of missionary endeavour. Subsequent work in the field has always been piecemeal and unco-ordinated, even though a degree of success has been achieved and valuable experience gained. The Federal Government's decision to launch a Mass Literacy Campaign in 1982 is primarily a political response to the needs and exigencies of a developing country rich both in natural and manpower resources. The campaign is seen not only as a necessary means of creating a permanently literate society within ten years but also as an assertion of the nation's unity. The problems of undertaking such a project are immensely complicated by the plethora of local languages and cultures, the preservation of which is seen to be imperative. But the campaign can succeed if the crucial issues identified in the article — functionality, personnel, training and materials, motivation, and above all the language to be used as the medium of literacy education — are resolved; if assistance from national development organisations and international bodies is matched by the determination of the government to create an environment capable of sustaining and reinforcing literacy and conducive to the use of the skills acquired; and if the illiterate respond with initiative and perseverence to the opportunity offered them.

  14. Indoor air quality issues related to the acquisition of conservation in commercial buildings

    SciTech Connect

    Baechler, M.C.; Hadley, D.L.; Marseille, T.J.

    1990-09-01

    The quality of indoor air in commercial buildings is dependent on the complex interaction between sources of indoor pollutants, environmental factors within buildings such as temperature and humidity, the removal of air pollutants by air-cleaning devices, and the removal and dilution of pollutants from outside air. To the extent that energy conservation measures (ECMs) may affect a number of these factors, the relationship between ECMs and indoor air quality is difficult to predict. Energy conservation measures may affect pollutant levels in other ways. Conservation measures, such as caulking and insulation, may introduce sources of indoor pollutants. Measures that reduce mechanical ventilation may allow pollutants to build up inside structures. Finally, heating, ventilation, and air-conditioning (HVAC) systems may provide surface areas for the growth of biogenic agents, or may encourage the dissemination of pollutants throughout a building. Information about indoor air quality and ventilation in both new and existing commercial buildings is summarized in this report. Sick building syndrome and specific pollutants are discussed, as are broader issues such as ventilation, general mitigation techniques, and the interaction between energy conservation activities and indoor air quality. Pacific Northwest Laboratory (PNL) prepared this review to aid the Bonneville Power Administration (Bonneville) in its assessment of potential environmental effects resulting from conservation activities in commercial buildings. 76 refs., 2 figs., 19 tabs.

  15. Radioactivity in books printed in Japan: its source and relation to the year of issue.

    PubMed

    Kobashi, A

    1996-06-01

    The radioactivities of the naturally occurring radionuclides (226Ra, 228Ra, 228Th and 40K) and a fallout nuclide (137Cs) in books produced in Japan in the 20th century were measured by gamma-ray spectrometry to obtain information on radiation emitted from books. The respective concentration ranges of 226Ra, 228Ra, 228Th, 40K, and 137Cs were 0.2-6.4, 0.4-11.2, 0.3-11.3, 1-112, and 0-3 Bq kg-1. X-ray diffraction spectra of the papers used in book printing showed that pyrophyllite, talc, kaolinite, and calcium carbonate were contained as fillers. A comparison of the radioactivity contents of the pulp and filler indicated that most of 226Ra, 228Ra, and 228Th in the books was present in the filler whereas 137Cs was in the pulp. The pattern of the concentration of each nuclide vs. the year of issue of the book was investigated. Patterns for the naturally occurring radionuclides were similar and were explained by the kinds of filler used. The pattern for 137Cs differed from the patterns of the naturally occurring radionuclides, having a marked peak in the mid-1960s. PMID:8840719

  16. Review and Prioritization of Technical Issues Related to Burnup Credit for LWR Fuel

    SciTech Connect

    Parks, C V; DeHart, M D; Wagner, John C

    2000-03-13

    This report has been prepared to review relevant background information and provide technical discussion that will help initiate a PIRT (Phenomena Identification and Ranking Tables) process for use of burnup credit in light-water reactor (LWR) spent fuel storage and transport cask applications. The PIRT process will be used by the NRC Office of Nuclear Regulatory Research to help prioritize and guide a coordinated program of research and as a means to obtain input/feedback from industry and other interested parties. The review and discussion in this report are based on knowledge and experience gained from work performed in the United States and other countries. Current regulatory practice and perceived industry needs are also reviewed as a background for prioritizing technical needs that will facilitate safe practice in the use of burnup credit. Relevant physics and analysis phenomenon are identified, and an assessment of their importance to burnup credit implementation is given. Finally, phenomena that need to be better understood for effective licensing, together with technical issues that require resolution, are presented and discussed in the form of a prioritization ranking and initial draft program plan.

  17. Cyanide hazards to plants and animals from gold mining and related water issues

    USGS Publications Warehouse

    Eisler, R.; Wiemeyer, Stanley N.

    2004-01-01

    Highly toxic sodium cyanide (NaCN) is used by the international mining community to extract gold and other precious metals through milling of high-grade ores and heap leaching of low-grade ores (Korte et al. 2000). The process to concentrate gold using cyanide was developed in Scotland in 1887 and was used almost immediately in the Witwatersrand gold fields of the Republic of South Africa. Heap leaching with cyanide was proposed by the U.S. Bureau of Mines in 1969 as a means of extracting gold from low-grade ores. The gold industry adopted the technique in the 1970s, soon making heap leaching the dominant technology in gold extraction (Da Rosa and Lyon 1997). The heap leach and milling processes, which involve dewatering of gold-bearing ores, spraying of dilute cyanide solutions on extremely large heaps of ores containing low concentrations of gold, or the milling of ores with the use of cyanide and subsequent recovery of the gold-cyanide complex, have created a number of serious environmental problems affecting wildlife and water management. In this account, we review the history of cyanide use in gold mining with emphasis on heap leach gold mining, cyanide hazards to plants and animals, water management issues associated with gold mining, and proposed mitigation and research needs.

  18. Assessment of the food safety issues related to genetically modified foods.

    PubMed

    Kuiper, H A; Kleter, G A; Noteborn, H P; Kok, E J

    2001-09-01

    International consensus has been reached on the principles regarding evaluation of the food safety of genetically modified plants. The concept of substantial equivalence has been developed as part of a safety evaluation framework, based on the idea that existing foods can serve as a basis for comparing the properties of genetically modified foods with the appropriate counterpart. Application of the concept is not a safety assessment per se, but helps to identify similarities and differences between the existing food and the new product, which are then subject to further toxicological investigation. Substantial equivalence is a starting point in the safety evaluation, rather than an endpoint of the assessment. Consensus on practical application of the principle should be further elaborated. Experiences with the safety testing of newly inserted proteins and of whole genetically modified foods are reviewed, and limitations of current test methodologies are discussed. The development and validation of new profiling methods such as DNA microarray technology, proteomics, and metabolomics for the identification and characterization of unintended effects, which may occur as a result of the genetic modification, is recommended. The assessment of the allergenicity of newly inserted proteins and of marker genes is discussed. An issue that will gain importance in the near future is that of post-marketing surveillance of the foods derived from genetically modified crops. It is concluded, among others that, that application of the principle of substantial equivalence has proven adequate, and that no alternative adequate safety assessment strategies are available. PMID:11576435

  19. Current issues relating to the transfusion of stored red blood cells.

    PubMed

    Zimrin, A B; Hess, J R

    2009-02-01

    The development of blood storage systems allowed donation and transfusion to be separated in time and space. This separation has permitted the regionalization of donor services with subsequent economies of scale and improvements in the quality and availability of blood products. However, the availability of storage raises the question of how long blood products can and should be stored and how long they are safe and effective. The efficacy of red blood cells was originally measured as the increment in haematocrit and safety began with typing and the effort to reduce the risk of bacterial contamination. Appreciation of a growing list of storage lesions of red blood cells has developed with our increasing understanding of red blood cell physiology and our experience with red blood cell transfusion. However, other than frank haemolysis, rare episodes of bacterial contamination and overgrowth, the reduction of oxygen-carrying capacity associated with the failure of some transfused cells to circulate, and the toxicity of lysophospholipids released from membrane breakdown, storage-induced lesions have not had obvious correlations with safety or efficacy. The safety of red blood cell storage has also been approached in retrospective epidemiologic studies of transfused patients, but the results are frequently biased by the fact that sicker patients are transfused more often and blood banks do not issue blood products in a random order. Several large prospective studies of the safety of stored red blood cells are planned. PMID:19152602

  20. Related Services for Handicapped Students: Legal Considerations. Research & Resources on Special Education: Issue II.

    ERIC Educational Resources Information Center

    National Conference of State Legislatures, Washington, DC.

    The paper examines current problems, controversies, legal disputes, and judicial rulings regarding the provision of related services to handicapped students. Following a section on background information, statutory requirements are specified and compared in chart form. A summary of legal disputes focuses on specific services (such as…

  1. Equal Employment Opportunity for Racial and Ethnic Minorities: Affirmative Action, Reverse Discrimination, and Related Issues.

    ERIC Educational Resources Information Center

    Uerling, Donald F.

    This paper discusses some basic constitutional and statutory principles related to affirmative action and reverse discrimination in employment of educational personnel. The specifications of the Equal Protection Clause of the 14th Amendment, Title VII of the Civil Rights Act of 1964, other statutes and regulations, and selected Supreme Court cases…

  2. A Discussion of the Literature and Issues Related to Effective Schooling.

    ERIC Educational Resources Information Center

    Edmonds, Ron

    Examined in this paper are the characteristics that distinguish successful schools from unsuccessful schools. Particular attention is given to the instructional success of schools with poor children. An extensive review of related literature illustrates the wide range of opinions held by educators and researchers on the subject. Reference is made…

  3. Educational Policy Issues Related to Computer Literacy in Rural School Systems.

    ERIC Educational Resources Information Center

    Clouse, R. Wilburn; Savage, Edward M.

    1981-01-01

    Presents and discusses the results of a survey of school districts in the state of Maine to determine if an educational disparity existed, related to computer science education, between rural and urban secondary schools in the state. Topics addressed include the importance of computer education and computer equipment availability. (Author/JL)

  4. An Analysis of Legal Issues Relating to the Least Restrictive Environment Standards

    ERIC Educational Resources Information Center

    Alquraini, Turki Abdullah

    2013-01-01

    The lack of clear language in the Individuals with Disabilities Education Act (IDEA), which is the federal law that governs the provision of special education and related services to children with disabilities in the USA, has led to inconsistencies in school districts' decisions regarding the least restrictive environment (LRE). This…

  5. 76 FR 52731 - On-Line Complaint Form for Service-Related Issues in Air Transportation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-23

    ... aviation economic, consumer protection, and civil rights requirements. Among other things, the office is... in compliance with federal aviation consumer protection and civil rights laws and what, if any... public to electronically submit aviation service-related complaints against air carriers. DATES:...

  6. Introduction to the issue regarding research regarding age related macular degeneration

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Blindness is the second greatest fear among the elderly. Age-related macular degeneration (AMD) is the leading cause of vision loss among the elderly in most industrialized nations. AMD first compromises central high acuity vision. Subsequently, all vision may be lost. AMD is a progressive retinal d...

  7. Relational Safety and Liberating Training Spaces: An Application with a Focus on Sexual Orientation Issues

    ERIC Educational Resources Information Center

    Hernandez, Pilar; Rankin, Pressley, IV

    2008-01-01

    This article describes and discusses a teaching case of a clinical training situation involving a gay marriage and family therapy student working with a same-sex affectional couple. The conceptual pillars of this teaching case, relational safety and liberating spaces, are advanced as illustrations of how the student developed his voice in the…

  8. Teachers for the Future: The Changing Nature of Society and Related Issues for the Teaching Workforce

    ERIC Educational Resources Information Center

    Skilbeck, Malcolm; Connell, Helen

    2004-01-01

    During the next decade, the teaching profession in Australia will be transformed. Due mainly to age related retirements there will be a massive turnover and a huge influx of new entrants. At the same time, it can be expected that there will be more exacting requirements and expectations of teachers as new professional standards are set to meet the…

  9. Single Parents: Career-Related Issues and Needs. ERIC Digest No. 75.

    ERIC Educational Resources Information Center

    Kerka, Sandra

    One in every four families with children under the age of 18 is a single-parent family (up from 1 of every 10 in 1970). The vast majority of single-parent families are low-income families consisting of a mother (usually with relatively little formal education) and her young children. Many female single heads of households are either displaced…

  10. Experimental microbiological issues related to biocontamination and human life support inside manned space modules

    NASA Astrophysics Data System (ADS)

    Canganella, Francesco; Rettberg, Petra; Bianconi, G.; di Mattia, E.; Taddei, A. R.; Iylin, V.; Novikova, N.; Fani, R.; Brigidi, P.; Vitali, B.; Candela, M.; Lobascio, C.; Saverino, A.; Simone, A.; Fossati, F.; Ferraris, M.

    The issue of biocontamination in manned space modules is very important for the International Space Station (ISS) as well as for future planetary bases. We have previously carried out re-search activities concerning biofilm metabolic activities of some reference bacteria on materials commonly used for aerospace industry and currently examined for space greenhouses. It was evaluated the effect on these materials of a mixture of emulsifiers produced by Pseudomonas strain AD1 and recently characterized by chemical methods. The following materials were in-vestigated: Kevlar, Nomex, Betacloth, aluminized Kapton, conventional Kapton, Combitherm, Mylar, copper foil, Teflon, aluminum, carbon fiber composite, aluminum thermo-dissipating tex-tile, aluminum tape, Zylon, Ergoflex, Vectran. Results showed a diverse affinity of materials for bacterial biofilm formation and occasionally sessile colonization was rejected. Pre-conditioning with the emulsifying extract led in some cases to a diminish of biofilm dehydrogenase activity and development compared to untreated materials, taking into account both concentrations and experimental conditions. This also concerned the relationship between the physical traits of materials and the level of bacterial biofilm developed under the experimental conditions. Presently we are investigating microbial biofilm development on either conventional or innova-tive space materials, experimentally treated by biological or chemo-physical coating. VIABLE ISS is a flight experiment concerning the exposure of these materials inside an ISS module for about 4 years. Another initiative (MICHA) on progress is part of the MARS500 Programme, presently going on at the IBMP facility in Moscow. Data will be useful to select appropriate material to be used for life support hardware to decrease the risk of surface biocontamination and health problems inside space modules, a great challenge for both biological and medical research.

  11. Epidemiology of Burkholderia cepacia complex species recovered from cystic fibrosis patients: issues related to patient segregation.

    PubMed

    McDowell, Andrew; Mahenthiralingam, Eshwar; Dunbar, Kerstin E A; Moore, John E; Crowe, Mary; Elborn, J Stuart

    2004-07-01

    Studies of the prevalence of Burkholderia cepacia complex species amongst cystic fibrosis (CF) patients in different geographical regions, and the association between cross-infection and putative transmissibility markers, will further our understanding of these organisms and help to address infection-control issues. In this study, B. cepacia complex isolates from CF patients in different regions of Europe were analysed. Isolates were examined for B. cepacia complex species and putative transmissibility markers [cable pilin subunit gene (cblA) and the B. cepacia epidemic strain marker (BCESM)]. Sporadic and cross-infective strains were identified by random amplification of polymorphic DNA (RAPD). In total, 79% of patients were infected with Burkholderia cenocepacia (genomovar III), 18% with Burkholderia multivorans (genomovar II) and less than 5% of patients with B. cepacia (genomovar I), Burkholderia stabilis (genomovar IV) or Burkholderia vietnamiensis (genomovar V). The cblA and BCESM transmissibility markers were only detected in strains of B. cenocepacia. The BCESM was a more sensitive marker for transmissible B. cenocepacia strains than cblA, although sporadic B. cenocepacia strains containing the BCESM, but lacking cblA, were also observed. Furthermore, clusters of cross-infection with transmissibility marker-negative strains of B. multivorans were identified. In conclusion, B. cenocepacia was the greatest cause of cross-infection, and the most widely distributed B. cepacia complex species, within these CF populations. However, cross-infection was not exclusive to B. cenocepacia and cblA and the BCESM were not absolute markers for transmissible B. cenocepacia, or other B. cepacia complex strains. It is therefore suggested that CF centres cohort patients based on the presence or absence of B. cepacia complex infection and not on the basis of transmissibility marker-positive B. cenocepacia as previously suggested. PMID:15184539

  12. Managerial implications of medical sales representative perceptions of job duties, job qualifications, and other performance-related issues.

    PubMed

    Tengilimoğlu, Dilaver; Korkmaz, Sezer; Akinci, Fevzi; Parsons, Amy L

    2004-01-01

    This study examined the perceptions of medical sales representatives of job related duties, job qualifications needed, and motivating factors and tested for differences based on gender, age, years of experience and education using prior research as a base. This study also explored issues that may arise between sales people and physicians. The authors surveyed 132 medical sales representatives from pharmaceutical firms located in Ankara, Turkey. The authors' findings highlight the need in Turkey for developing in-service training programs for medical sales representatives, especially in the areas related to technical aspects of the product, effective marketing and personal selling strategies, and consumer relations. Training in these areas will help salespeople to better manage the problems typically encountered in physician-sales representative relations. While the study was conducted in Turkey, the results are similar to findings in prior research conducted in other countries and therefore may be of interest to all sales managers. PMID:15914372

  13. Secondary school physics availability in an urban setting: Issues related to academic achievement and course offerings

    NASA Astrophysics Data System (ADS)

    Kelly, Angela M.; Sheppard, Keith

    2009-10-01

    High school physics is a gateway course for post-secondary study in science, and an essential component in the formation of students' scientific literacy. The opportunity to study physics is not universally available for children in U.S. schools, particularly in urban areas. Restricted science opportunities result in inequitable participation and a barrier to future participation in STEM-related fields. Although the national trend in physics enrollment has recently shown an increase, the percentage of participation is much lower for students in urban schools. We examined the availability of physics in New York City, and whether access was related to academic achievement measures, such as prior science performance, and graduation and college attendance percentages. High schools that offered physics were compared to those that did not, and patterns in types of available physics courses were examined. The findings substantiate the compelling need to explore the barriers to increased physics access and participation for urban youth.

  14. Oil, Water, and Wildlife: The Gulf of Mexico Disaster and Related Environmental Issues

    ScienceCinema

    Bickman, John W. [Purdue University, West Lafayette, Indiana, United States

    2010-09-01

    The BP Macondo oil field spill in the Gulf of Mexico is the largest oil spill in U.S. history and has the potential to impact sea turtle and marine mammal populations, and others. This presentation will review the genotoxic effects of oil exposure in wildlife and discuss the potential for an oil spill to impact wildlife populations. Whereas some aspects of a spill are predictable, each spill is different because oils are highly variable, as are the environments in which they occur. The presentation will discuss what has been learned from previous spills, including the Exxon Valdez and the soviet oil legacy in Azerbaijan, and the potential dangers of offshore oil development in the Arctic. Related Purdue University research efforts in oil-spill related engineering and science also will be highlighted.

  15. Oil, Water, and Wildlife: The Gulf of Mexico Disaster and Related Environmental Issues

    SciTech Connect

    Bickman, John W.

    2010-08-04

    The BP Macondo oil field spill in the Gulf of Mexico is the largest oil spill in U.S. history and has the potential to impact sea turtle and marine mammal populations, and others. This presentation will review the genotoxic effects of oil exposure in wildlife and discuss the potential for an oil spill to impact wildlife populations. Whereas some aspects of a spill are predictable, each spill is different because oils are highly variable, as are the environments in which they occur. The presentation will discuss what has been learned from previous spills, including the Exxon Valdez and the soviet oil legacy in Azerbaijan, and the potential dangers of offshore oil development in the Arctic. Related Purdue University research efforts in oil-spill related engineering and science also will be highlighted.

  16. A note on the compartmental analysis and related issues in laser Doppler flowmetry.

    PubMed

    Zhong, J; Nilsson, G E; Salerud, G E; Seifalian, A M

    1998-04-01

    Compartmental analysis (CA) in laser Doppler flowmetry (LDF) means deciphering the nutritional and thermoregulating flows from the measured perfusion flux. Based on the new theories proposed in [1] and [2], the CA is formulated here as an optimal approximation without directly involving the geometric information of the vessel network. It is seen that this approximation approach could also solve the biological zero (BZ) problem simultaneously, therefore, it actually provides a systematic solution to the BZ problem without estimating the BZ flux experimentally. In addition, the BZ problem with compartmental differences is reformulated, and the condition under which multiple compartments can be treated as a single one is investigated. The result, together with some computer simulations, showed that the theory in [2] is still an easy and useful approximation in practice. This note serves as an useful supplement to [1] and [2] and may help to solve and clarify some critical problems in LDF. PMID:9556971

  17. Semen production and fertility issues related to differences in genetic lines of boars.

    PubMed

    Sonderman, J P; Luebbe, J J

    2008-11-01

    Boars have been reported to differ in various characteristics important to productivity of AI units. These aspects include sensitivity to seasonal infertility, ejaculate volume x age interactions, optimum collection frequency, discard (trash) rate of ejaculates, age of puberty, libido and trainability, and semen shelf life. In addition to differences among individual boars, there were also identifiable differences among breeds, between purebreds and crossbreds, and between lines. The percentage of ejaculates discarded varied among seasons and among breeds within season, with maternal purebred lines being the most sensitive to warmer temperatures. These same lines were also slower to mature and produced fewer sperm per ejaculate. Breeds differed in the sustainability of motility in stored extended semen, and in farrowing rates. Boar centers need to factor breed differences into their decision-making processes to ensure adequate boar power and customer satisfaction. PMID:18783820

  18. Salt associated with oil and gas activities: Remediation and related issues

    SciTech Connect

    Deuel, L.E. Jr.

    1995-12-31

    Salt, or brine, are generic terms for the chemical compound sodium chloride. We all know it as a seasoning agent and preservative for foods. Ancient cultures and civilizations actually used salt as money for barter and trade for goods and services. Presently, salt in the oil patch can still be equated with money, but in terms of capital outlay rather than barter and trade. Hazardous wastes, heavy metals, hydrocarbons, and other substances, are perceived by the public as a greater environmental threat than salt, and thus receive greater corporate attention. However, in terms of actual damage to the environment and capital outlay necessary for remediation, all other constituents pale in comparison to salt. The primary source of salt associated with oil and gas activities is produced water, with produced solids, drilling muds, and cuttings a very distant second. Produced waters contain salt concentrations ranging from trace levels to 2.6 pounds per gallon of water. The average for production provinces in the continental United States is about 0.7 pounds per gallon. Salt wasting of land is considered complete and irreparable at a salt concentration in soil of 7,500 ppm. Salt damaged soils are classed as either saline, saline/sodic, or sodic. The only way to reclaim a saline soil is to flush it with fresh water. There is no miracle product or magic elixir that can do this job. A saline/sodic soil contains both excess salt and excess exchangeable (adsorbed) sodium. Remediation of a saline/sodic soil requires the addition of amendments to address the exchangeable sodium, prior to the addition of fresh water to flush the excess salt. Sodic soils are the most difficult to remediate because of their dispersed nature, and the innate difficulty of placing amendments in contact with the soil particles necessary for the exchange processes to occur.

  19. Scaling issues relating to phosphorus transfer from land to water in agricultural catchments

    NASA Astrophysics Data System (ADS)

    Brazier, R. E.; Heathwaite, A. L.; Liu, S.

    2005-03-01

    Various scales of input data exist to parameterise diffuse pollution models for the UK. For screening methodologies such as the phosphorus indicators tool—PIT [Heathwaite, A.L., Sharpley, A.N., Bechmann, M., 2003a. The conceptual basis for a decision support framework to assess the risk of phosphorus loss at the field scale across Europe. Journal of Plant Nutrition and Soil Science 166, 1-12; Heathwaite, A.L., Burke, S., Quinn, P.F., 2003b. The nutrient export risk matrix (the NERM) for strategic application of biosolids to agricultural land. International Association for Hydrological Sciences Publication 285, 1-9], which is applied throughout England and Wales, some assessment of the implications of using input data derived at different scales must be made. This work is further driven by practical issues such as licensing costs and data availability, which mean that not all data are readily accessible for all end users. This paper represents a first step towards quantifying the 'value-added' to model predictions by using input data derived at three different scales: 50×50 m, 1×1 km and 5×5 km. Model runs using PIT were carried out against observed phosphorus water quality data from the River Start and River Gara, which are the main sub-catchments of Slapton Ley, a grade 1 National Nature Reserve in southwest England. Model runs for the main 46 km 2 Slapton catchment were also undertaken. The results show that some improvement in the ability of the model to capture the observed water quality behaviour may be made by using higher resolution DEM data, though these improvements may be outweighed by the extra data processing and computational time. Conversely, model runs driven by the 5 km data demonstrate consistent under-prediction for all three test catchments, which is perhaps not surprising given the greater degree of averaging underlying datasets at this scale. Results from the 1 km datasets provide the best agreement with observed water quality data, and

  20. Global hydrobelts and hydroregions: improved reporting scale for water-related issues?

    NASA Astrophysics Data System (ADS)

    Meybeck, M.; Kummu, M.; Dürr, H. H.

    2013-03-01

    Global-scale water issues such as its availability, water needs or stress, or management, are mapped at various resolutions and reported at many scales, mostly along political or continental boundaries. As such, they ignore the fundamental heterogeneity of hydroclimates and natural boundaries of river basins. Here we describe the continental landmasses at two levels: eight hydrobelts strictly limited by river basins, defined at a 30' (0.5°) resolution, which are decomposed on continents as 26 hydroregions. The belts were defined and delineated, based primarily on the annual average temperature (T) and run-off (q), to maximise inter-belt differences and minimise intra-belt variability. This new global puzzle defines homogeneous and near-contiguous entities with similar hydrological and thermal regimes, glacial and postglacial basin histories, endorheism distribution and sensitivity to climate variations. The mid-latitude, dry and subtropical belts have northern and southern analogues and a general symmetry can be observed for T and q between them. The boreal and equatorial belts are unique. Population density between belts and between the continents varies greatly, resulting in pronounced differences between the belts with analogues in both hemispheres. Hydroregions (median size 4.7 M km2) are highly contrasted, with the average q ranging between 6 and 1393 mm yr-1 and the average T between -9.7 and +26.3 °C, and a population density ranging from 0.7 to 0.8 p km-2 for the North American boreal region and some Australian hydroregions to 280 p km-2 for some Asian hydroregions. The population/run-off ratio, normalised to a reference pristine region, is used to map and quantify the global population at risk of severe water quality degradation. Our initial tests suggest that hydrobelt and hydroregion divisions are often more appropriate than conventional continental or political divisions for the global analysis of river basins within the Earth system and of water

  1. The Law and Emergencies: Surveillance for Public Health–Related Legal Issues During Hurricanes Katrina and Rita

    PubMed Central

    Weiss, Rachel I.; McKie, Karen L.; Goodman, Richard A.

    2007-01-01

    Law influenced every aspect of the public health response to Hurricanes Katrina and Rita, from evacuation orders, to waivers of medical licensing requirements, to the clean-up of public health threats on private property. We used public health surveillance of news reports to identify and characterize legal issues arising during the disaster response in 5 Gulf Coast states. Data collected from news reports of the events in real time were followed-up by interviews with selected state legal and emergency management officials. Our analysis indicates the value of surveillance during and after emergency responses in identifying public health–related legal issues and helps to inform the strengthening of legal preparedness frameworks for future disasters. PMID:17413083

  2. Talking about epilepsy: Challenges parents face when communicating with their child about epilepsy and epilepsy-related issues.

    PubMed

    O'Toole, Stephanie; Lambert, Veronica; Gallagher, Pamela; Shahwan, Amre; Austin, Joan K

    2016-04-01

    The aim of this qualitative study was to explore the challenges that parents of children with epilepsy experienced when engaging in dialog with their child about epilepsy and epilepsy-related issues. Using a qualitative exploratory approach, interviews were conducted with 34 parents of children with epilepsy (aged 6-16years), consisting of 27 mothers and 7 fathers. Data were transcribed verbatim and thematically analyzed. Findings revealed five main themes: normalizing epilepsy, the invisibility of epilepsy, information concealment, fear of misinforming the child, and difficulty in discussing particular epilepsy-related issues. Many of the communicative challenges experienced by parents impacted on their ability to engage openly in parent-child dialog about epilepsy in the home. Parents face specific challenges when choosing to communicate with their child about epilepsy, relating to creating a sense of normality, reducing fear of causing their child worry, and having a lack of epilepsy-related knowledge. Healthcare professionals who work closely with families living with epilepsy should remain mindful of the importance of discussing family communication surrounding epilepsy and the challenges parents of children with epilepsy face when talking about epilepsy within the home. PMID:26900774

  3. Advice about Work-Related Issues to Peers and Employers from Head and Neck Cancer Survivors

    PubMed Central

    Dewa, Carolyn S.; Trojanowski, Lucy; Tamminga, Sietske J.; Ringash, Jolie; McQuestion, Maurene; Hoch, Jeffrey S.

    2016-01-01

    Purpose The purpose of this exploratory and descriptive study is to contribute to the sparse return-to-work literature on head and neck cancer (HNC) survivors. Interview participants were asked to reflect upon their work-related experience with cancer by answering two specific questions: (1) What advice would you give someone who has been newly diagnosed with head and neck cancer? (2) What advice would you give to employers of these people? Methods Data were gathered through 10 individual semi-structured in-depth interviews with HNC clinic patients at a regional cancer center’s head and neck clinic in Ontario, Canada. A constant comparative method of theme development was used. Codes identified in and derived from the data were discussed by research team members until consensus was reached. Codes with similar characteristics were grouped together and used to develop overarching themes. Results Work-related advice for peers focused on personal self-care and interactions within workplaces. Work-related advice to employers focused on demonstrating basic human values as well as the importance of communication. Discussion The study results suggest HNC clinic patients should be proactive with employers and help to set reasonable expectations and provide a realistic plan for work to be successfully completed. HNC clinic patients should develop communication skills to effectively disclose their cancer and treatment to employers. Conclusions In this exploratory study, HNC clinic patients’ advice was solution-focused underscoring the importance of self-care and pro-active communication and planning with employers. Employers were advised to demonstrate core human values throughout all phases of the work disability episode beginning at diagnosis. PMID:27070654

  4. Risk management regulations of 1996: Why is this a community relations issue?

    SciTech Connect

    Chaloux, S.

    1997-05-01

    The US EPA`s risk management regulations will require approximately 66,000 facilities nationwide to identify and disclose information about hazard assessments (including such worst-case scenarios as the off-site impact of accidental releases of cutely toxic or highly flammable materials), emergency response capabilities, and risk management efforts. These requirements were initiated to let information from these assessments drive action (prevention and preparedness) and stimulate dialogue on the local level. A brief summary of the major aspects of the final rule and their public relations implications is presented.

  5. Electronic structure of the quantum spin Hall parent compound CdTe and related topological issues

    NASA Astrophysics Data System (ADS)

    Ren, Jie; Bian, Guang; Fu, Li; Liu, Chang; Wang, Tao; Zha, Gangqiang; Jie, Wanqi; Neupane, Madhab; Miller, T.; Hasan, M. Z.; Chiang, T.-C.

    2014-11-01

    Cadmium telluride (CdTe), a compound widely used in devices, is a key base material for the experimental realization of the quantum spin Hall phase. We report herein a study of the electronic structure of CdTe by angle-resolved photoemission spectroscopy from well-ordered (110) surfaces. The results are compared with first-principles calculations to illustrate the topological distinction between CdTe and a closely related compound HgTe. Through a theoretical simulation a topological phase transition as well as the Dirac-Kane semimetal phase at the critical point was demonstrated in the mixed compound H gxC d1 -xTe .

  6. Methamphetamine-induced toxicity: an updated review on issues related to hyperthermia

    PubMed Central

    Matsumoto, Rae R.; Seminerio, Michael J.; Turner, Ryan C.; Robson, Matthew J.; Nguyen, Linda; Miller, Diane B.; O’Callaghan, James P.

    2015-01-01

    Reports of methamphetamine-related emergency room visits suggest that elevated body temperature is a universal presenting symptom, with lethal overdoses generally associated with extreme hyperthermia. This review summarizes the available information on methamphetamine toxicity as it pertains to elevations in body temperature. First, a brief overview of thermoregulatory mechanisms is presented. Next, central and peripheral targets that have been considered for potential involvement in methamphetamine hyperthermia are discussed. Finally, future areas of investigation are proposed, as further studies are needed to provide greater insight into the mechanisms that mediate the alterations in body temperature elicited by methamphetamine. PMID:24836729

  7. Scientific issues related to Codex Alimentarius goals: a review of principles, with examples.

    PubMed

    Somogyi, Arpad; Hathcock, John; Biesalski, Hans Konrad; Blumberg, Jeffrey B; Antoine, Jean-Michel; Edwards, Gareth; Prock, Peter

    2011-06-01

    The Codex Alimentarius provides the food standards and guidelines recognized by the World Trade Organization as the primary authority for use in settlement of related trade disputes. Codex bases its decisions primarily on scientific principles and evidence, although other legitimate factors such as economic and societal values may be considered. Codex has two primary aims: to protect consumers' health and assure fair practices in food trade. Codex documents may provide templates for individual nations but are not binding for domestic policies. Despite many advances over the last couple of decades, misunderstandings and controversies have interfered with important aspects of progress which Codex needs to accomplish, especially in the areas of claims of benefits related to food or nutrient consumption and the establishment of the safety of these items. Claims for health benefits should be based on the totality of available scientific evidence, including observational data collected from large populations as well as the results from randomized clinical trials. Safety should be evaluated by risk assessment on high quality experimental data, with anecdotal information having a lesser role. Regulatory policy would be improved if "history of safe use" were to be better defined and described. PMID:21382429

  8. Natural Circulation Patterns in the VHTR Air-Ingress Accident and Related Issues

    SciTech Connect

    Chang Ho Oh; Eung Soo Kim; Hyung Seok Kang

    2010-10-01

    A natural circulation pattern in a Very High Gas-Cooled Reactor during a hypothetical air-ingress accident has been investigated using computational fluid dynamic (CFD) methods in order to compare with the previous 1-D flow path model for the air-ingress analyses. The GT-MHR 600 MWt reactor was selected to be the reference design and modeled by a half symmetric 3-D geometry using FLUENT 6.3, a commercial CFD code. The simulation was carried out as steady-state calculations, and the boundary conditions were either assumed or provided from the 1-D GAMMA code results. Totally, 12 different cases have been estimated, and many notable findings and results have been obtained in this study. According to the simulations, the natural circulation pattern in the reactor was quite different from the previous 1-D assumptions. A large re-circulation flow with thermal stratification phenomena was clearly observed in the hot-leg and the lower plenum in the 3-D model. This re-circulation flow provided approximately an order faster air-ingress speed (0.46 m/s in superficial velocity) than previously predicted values by 1-D modeling (0.02~0.03 m/s). It indicates that the 1-D air-ingress modeling may significantly distort the air-ingress scenario and consequences. In addition, the complicated natural circulation pattern is eventually expected to lead to very complex graphite oxidations and corrosion patterns.

  9. Issues Related to Cleaning Complex Geometry Surfaces with ODC-Free Solvents

    NASA Technical Reports Server (NTRS)

    Bradford, Blake F.; Wurth, Laura A.; Nayate, Pramod D.; McCool, Alex (Technical Monitor)

    2001-01-01

    Implementing ozone depleting chemicals (ODC)-free solvents into full-scale reusable solid rocket motor cleaning operations has presented problems due to the low vapor pressures of the solvents. Because of slow evaporation, solvent retention is a problem on porous substrates or on surfaces with irregular geometry, such as threaded boltholes, leak check ports, and nozzle backfill joints. The new solvents are being evaluated to replace 1,1,1-trichloroethane, which readily evaporates from these surfaces. Selection of the solvents to be evaluated on full-scale hardware was made based on results of subscale tests performed with flat surface coupons, which did not manifest the problem. Test efforts have been undertaken to address concerns with the slow-evaporating solvents. These concerns include effects on materials due to long-term exposure to solvent, potential migration from bolthole threads to seal surfaces, and effects on bolt loading due to solvent retention in threads. Tests performed to date have verified that retained solvent does not affect materials or hardware performance. Process modifications have also been developed to assist drying, and these can be implemented if additional drying becomes necessary.

  10. Natural Circulation Patterns in the VHTR Air-Ingress Accident and Related Issues

    SciTech Connect

    Chang H. Oh; Eung S. Kim

    2012-08-01

    Natural circulation patterns in the VHTR during a hypothetical air-ingress accident have been investigated using computational fluid dynamic (CFD) methods in order to compare results from the previous 1-D model which was developed using GAMMA code for the air-ingress analyses. The GT-MHR 600 MWt reactor was selected to be the reference design and modeled by a half symmetric 3-D geometry using FLUENT 6.3, a commercial CFD code. CFD simulations were carried out as the steady-state calculation, and the boundary conditions were either assumed or provided from the 1-D GAMMA code results. Totally, 12 different cases have been reviewed, and many notable results have been obtained through in this work. According to the simulations, natural circulation patterns in the reactor were quite different from the previous 1-D assumptions. A large re-circulation flow with thermal stratification phenomena was clearly observed in the hot-leg and the lower plenum in the 3-D model. This re-circulation flow provided about an order faster air-ingress speed (0.46 m/s in superficial velocity) than previously predicted by 1-D modeling (0.02~0.03 m/s). It indicates that the 1-D air-ingress modeling may significantly distort the air-ingress scenario and consequences. In addition, complicated natural circulation patterns are eventually expected to result in very complex graphite oxidations and corrosion behaviors.

  11. Health-related quality of life in mucopolysaccharidosis: looking beyond biomedical issues.

    PubMed

    Hendriksz, Christian J; Berger, Kenneth I; Lampe, Christina; Kircher, Susanne G; Orchard, Paul J; Southall, Rebecca; Long, Sarah; Sande, Stephen; Gold, Jeffrey I

    2016-01-01

    The mucopolysaccharidoses (MPS) comprise a heterogeneous family of rare, genetic lysosomal storage disorders that result in severe morbidity and reduced life expectancy. Emerging treatments for several of these disorders have triggered the search for clinically relevant biomarkers and clinical markers associated with treatment efficacy in populations and individuals. However, biomedical measures do not tell the whole story when characterizing a complex chronic disorder such as MPS. Health-related quality of life (HRQoL) tools that utilize patient reported outcomes to address patient parameters such as symptoms (pain, fatigue, psychological health), functioning (activity and limitations), or quality of life, have been used to supplement traditional biomedical endpoints. Many of these HRQoL tools have demonstrated that quality of life is negatively impacted in patients with MPS. There is both the opportunity and need to formally standardize and validate HRQoL tools for the different MPS disorders. PMID:27561270

  12. Adherence-related issues in adolescents and young adults with hematological disorders.

    PubMed

    Leader, Avi; Raanani, Pia

    2014-01-01

    Nonadherence to medical recommendations is a widespread problem well documented in a multitude of clinical settings. Nonadherence may adversely affect clinical outcomes such as survival and quality of life and increase health-care-related costs. An understanding of the factors driving nonadherence is key to developing effective adherence-enhancing interventions (AEIs). There are ongoing attempts in contemporary adherence research to better define the various components of adherence, to find optimal measures of adherence and correlations with clinical outcomes, and to create a classification system for AEIs. Nonadherence is also widely prevalent among adolescents and young adults (AYAs) with chronic hematological diseases, affecting up to 50% of patients and increasing with age. Combined use of objective (i.e. electronic monitoring, EM) and subjective (i.e. self-report) measures of adherence may be the preferred approach to assess adherence. The unique physical, social and emotional aspects of the AYA life stage are closely related to intricate causes of nonadherence in AYAs such as problems in transition to adult care. Until proven otherwise, the empirical target in AYAs with hematological disorders should be perfect adherence. Multilevel AEIs, EM feedback and behavioral interventions are among the most effective types of AEIs. Despite the magnitude of the problem, only a handful of AEIs have been evaluated among AYAs with hematological disorders. Thus, this is a field with unmet needs warranting high-quality trials using standardized and well-specified assessment methods and interventions. This review discusses the prevalence, definition, causes and clinical implications of nonadherence among AYAs with hematological disorders, along with strategies to measure and improve adherence. PMID:25228561

  13. Current situation and issues using maternal and child health-related information in the "Healthy parents and children 21" campaign across municipalities in Japan.

    PubMed

    Uehara, Ritei; Shinohara, Ryoji; Akiyama, Yuka; Ichikawa, Kaori; Ojima, Toshiyuki; Tamakoshi, Koji; Matsuura, Kencho; Yamazaki, Yoshihisa; Yamagata, Zentaro

    2016-01-01

    maternal and child health-related information, coordinating projects about child abuse with the prefectures might be associated with an increase in using the information. In addition to collecting and analyzing maternal and child health-related information provided by municipalities, prefectures should help municipalities coordinate projects about those issues to increase the use of the information in municipalities. PMID:27535812

  14. Geoethical issues in long-term assessment of geohazards and related mitigation policies

    NASA Astrophysics Data System (ADS)

    Tinti, Stefano; Armigliato, Alberto

    2015-04-01

    Long-term assessment of large-impact and relatively (or very) infrequent geohazards like earthquakes, tsunamis and volcanic eruptions is nowadays a common practice for geoscientists and many groups have been and are involved in producing global and regional hazard maps in response of an increasing demand of the society. Though the societal needs are the basic motivations for such studies, often this aspect is not pondered enough and a lack of communication between geoscientists and the society might be a serious limit to the effective exploitation of the hazard assessment products and to the development of adequate mitigation policies. This paper is an analysis of the role of geoscientists in the process of the production of long-term assessments of dangerous natural phenomena (such as mapping of seismic, tsunami and volcanic hazards), with special emphasis given to the role of communicators and disseminators (with respect to the general public, to authorities, to restricted specialized audiences…), but also of providers of active support to the planners who should be given key elements for making decision. Geoethics imposes geoscientists to take clear and full responsibilities on the products resulting from their assessments, but also to be aware that these products are valuable insofar they are scientifically sound, known, understandable, and utilizable by a wide universe of users.

  15. An Examination of Data Confidentiality and Disclosure Issues Related to Publication of Empirical ROC Curves

    PubMed Central

    Matthews, Gregory J.; Harel, Ofer

    2013-01-01

    Rationale and Objectives Grant funding institutions often require organizations to share their collected data as widely as possible while safeguarding the privacy of individuals. Summaries based on these data are often released. Here, the receiver operating characteristic (ROC) curve is explored for potential statistical disclosures in the presence of auxiliary data. Materials and Methods Formulas are introduced for calculating the missing data points from the full data set, given that a user has an empirical ROC curve and a subset of the data used to generate such a curve. Further, a discussion of the plausibility of this scenario is presented. Results Diagnostic test data were simulated and an ROC curve was produced. Using a subset of the true data and the points on the empirical ROC curve, an attempt was made to reproduce the missing parts of the data. Disease statuses were able to be determined exactly, whereas test scores were solved for up to their rank. Conclusions If an individual or organization possessed the points of an empirical ROC curve and a subset of the true data, the true data underlying the ROC curve can be reproduced relatively accurately. As a result, the release of summaries of data, including the ROC curve, must be given careful thought before their release from a statistical disclosure perspective. PMID:23747154

  16. Genetic structure of populations and conservation issues relating to an endangered catfish, Clarias batrachus, in India.

    PubMed

    Khedkar, Gulab D; Tiknaik, Anita; Kalyankar, Amol D; A, Chandra Sekhar Reddy; Khedkar, Chandraprakash D; Ron, Tetsuzan Benny; Haymer, David

    2016-01-01

    The Asian catfish, Clarias batrachus (Linnaeus, 1758), is a highly valued species endemic to India that is currently in drastic decline in most of its natural habitat. The present study was undertaken to document the genetic structure of populations of this species using mitochondrial DNA markers, specifically from the cytochrome B and D-loop regions. Specimens from eight wild populations were collected and analyzed from different regions in India. The genetic variation within and among populations was evaluated using a range of descriptive statistics. The analysis described here provides a broad and consistent view of population structure and demographic history of populations of C. batrachus. Although there was some genetic structuring consistent with regional differences, all eight populations examined here showed relatively low levels of genetic variation in terms of both haplotype and nucleotide diversities in the different analyses used. However, a number of private haplotypes were discovered, and this may provide valuable information for future selective breeding program and conservation management. The results may aid in the design and implementation of strategies for the future management of this endangered catfish C. batrachus in India. PMID:25103426

  17. Analysis on the distinguishing features of traditional Chinese therapeutics and related statistical issues.

    PubMed

    Hu, Jingqing; Qiao, Jie; Kang, Deying; Liu, Baoyan

    2011-06-01

    Traditional Chinese medicine (TCM) is one of the rarely existing ancient traditional medicines that hold systematic theories as well as preventative and therapeutic methods for diseases in practice. From the 1950s, such research methods as mathematics, statistics, and data mining (DM) have been gradually introduced to TCM studies, making it more scientific. Meanwhile, the distinct features of TCM theories and diagnostic-model have constantly challenged the methodology of statistics. This paper introduces the following scientific features of traditional Chinese therapeutics: 1) its goal is to balance the functions and conditions of human body; 2) it emphasizes on holism and individualization; 3) it stresses the longitudinal regulation and evaluation mode, which is a circle of syndrome diagnosis, treatment and evaluation; 4) the interventions of TCM are abundant, compound and natural; and 5) humanistic thought is everywhere. Some statistical problems are raised based on these features. First, complex statistical methods that can analyze subjective indexes and latent variables, multidimensional and multistage data, non-equilibrium designed studies, and longitudinal data are required. Second, comprehensive evaluation on multiple-target mechanism has been brought in by combination treatment. Third, there is a need to analyze how humanity and related cultural factors may influence the effect of interventions. Thus, promoting implemented studies of statistics as well as carrying out the TCM scientific propositions have become the common expectations of both TCM and modern medicine. PMID:21695626

  18. A preliminary examination of audience-related communications issues for the Hanford Environmental Dose Reconstruction Project

    SciTech Connect

    Holmes, C.W.

    1991-04-01

    The Hanford Environmental Dose Reconstruction (HEDR) Project will estimate radiation doses people may have received from exposure to radioactive materials released during past operations at the US Department of Energy's (DOE) Hanford Site near Richland, Washington. The HEDR Project was initiated in response to public concerns about possible health impacts from past releases of radioactive materials from Hanford. The TSP recognized early in the project that special mechanisms would be required to effectively communicate to the many different concerned audiences. Accordingly, the TSP directed PNL to examine methods for communicating causes and effects of uncertainties in the dose estimates. After considering the directive and discussing it with the Communications Subcommittee of the TSP, PNL undertook a broad investigation of communications methods to consider for inclusion in the TSP's current communications program. As part of this investigation, a literature review was conducted regarding risk communications. A key finding was that, in order to successfully communicate risk-related information, a thorough understanding of the knowledge level, concerns and information needs of the intended recipients (i.e., the audience) is necessary. Hence, a preliminary audience analysis was conducted as part of the present research. This report summarizes the results of this analysis. 1 ref., 9 tabs.

  19. Reduction of dioxin-like toxicity in effluents by additional wastewater treatment and related effects in fish.

    PubMed

    Maier, Diana; Benisek, Martin; Blaha, Ludek; Dondero, Francesco; Giesy, John P; Köhler, Heinz-R; Richter, Doreen; Scheurer, Marco; Triebskorn, Rita

    2016-10-01

    Efficiency of advanced wastewater treatment technologies to reduce micropollutants which mediate dioxin-like toxicity was investigated. Technologies compared included ozonation, powdered activated carbon and granular activated carbon. In addition to chemical analyses in samples of effluents, surface waters, sediments, and fish, (1) dioxin-like potentials were measured in paired samples of effluents, surface waters, and sediments by use of an in vitro biotest (reporter gene assay) and (2) dioxin-like effects were investigated in exposed fish by use of in vivo activity of the mixed-function, monooxygenase enzyme, ethoxyresorufin O-deethylase (EROD) in liver. All advanced technologies studied, based on degradation or adsorption, significantly reduced dioxin-like potentials in samples and resulted in lesser EROD activity in livers of fish. Results of in vitro and in vivo biological responses were not clearly related to quantification of targeted analytes by use of instrumental analyses. PMID:27262214

  20. Seasonal Patterns of Soil Respiration and Related Soil Biochemical Properties under Nitrogen Addition in Winter Wheat Field

    PubMed Central

    Liang, Guopeng; Houssou, Albert A.; Wu, Huijun; Cai, Dianxiong; Wu, Xueping; Gao, Lili; Li, Jing; Wang, Bisheng; Li, Shengping

    2015-01-01

    Understanding the changes of soil respiration under increasing N fertilizer in cropland ecosystems is crucial to accurately predicting global warming. This study explored seasonal variations of soil respiration and its controlling biochemical properties under a gradient of Nitrogen addition during two consecutive winter wheat growing seasons (2013–2015). N was applied at four different levels: 0, 120, 180 and 240 kg N ha-1 year-1 (denoted as N0, N12, N18 and N24, respectively). Soil respiration exhibited significant seasonal variation and was significantly affected by soil temperature with Q10 ranging from 2.04 to 2.46 and from 1.49 to 1.53 during 2013–2014 and 2014–2015 winter wheat growing season, respectively. Soil moisture had no significant effect on soil respiration during 2013–2014 winter wheat growing season but showed a significant and negative correlation with soil respiration during 2014–2015 winter wheat growing season. Soil respiration under N24 treatment was significantly higher than N0 treatment. Averaged over the two growing seasons, N12, N18 and N24 significantly increased soil respiration by 13.4, 16.4 and 25.4% compared with N0, respectively. N addition also significantly increased easily extractable glomalin-related soil protein (EEG), soil organic carbon (SOC), total N, ammonium N and nitrate N contents. In addition, soil respiration was significantly and positively correlated with β-glucosidase activity, EEG, SOC, total N, ammonium N and nitrate N contents. The results indicated that high N fertilization improved soil chemical properties, but significantly increased soil respiration. PMID:26629695

  1. Analysis of environmental issues related to small-scale hydroelectric development. III. Water level fluctuation

    SciTech Connect

    Hildebrand, S.G.

    1980-10-01

    Potential environmental impacts in reservoirs and downstream river reaches below dams that may be caused by the water level fluctuation resulting from development and operation of small scale (under 25MW) hydroelectric projects are identified. The impacts discussed will be of potential concern at only those small-scale hydroelectric projects that are operated in a store and release (peaking) mode. Potential impacts on physical and chemical characteristics in reservoirs resulting from water level fluctuation include resuspension and redistribution of bank and bed sediment; leaching of soluble organic matter from sediment in the littoral zone; and changes in water quality resulting from changes in sediment and nutrient trap efficiency. Potential impacts on reservoir biota as a result of water level fluctuation include habitat destruction and the resulting partial or total loss of aquatic species; changes in habitat quality, which result in reduced standing crop and production of aquatic biota; and possible shifts in species diversity. The potential physical effects of water level fluctuation on downstream systems below dams are streambed and bank erosion and water quality problems related to resuspension and redistribution of these materials. Potential biological impacts of water level fluctuation on downstream systems below dams result from changes in current velocity, habitat reduction, and alteration in food supply. These alterations, either singly or in combination, can adversely affect aquatic populations below dams. The nature and potential significance of adverse impacts resulting from water level fluctuation are discussed. Recommendations for site-specific evaluation of water level fluctuation at small-scale hydroelectric projects are presented.

  2. Breeding site selection by coho salmon (Oncorhynchus kisutch) in relation to large wood additions and factors that influence reproductive success

    USGS Publications Warehouse

    Clark, Steven M.; Dunham, Jason B.; McEnroe, Jeffery R.; Lightcap, Scott W.

    2014-01-01

    The fitness of female Pacific salmon (Oncorhynchus spp.) with respect to breeding behavior can be partitioned into at least four fitness components: survival to reproduction, competition for breeding sites, success of egg incubation, and suitability of the local environment near breeding sites for early rearing of juveniles. We evaluated the relative influences of habitat features linked to these fitness components with respect to selection of breeding sites by coho salmon (Oncorhynchus kisutch). We also evaluated associations between breeding site selection and additions of large wood, as the latter were introduced into the study system as a means of restoring habitat conditions to benefit coho salmon. We used a model selection approach to organize specific habitat features into groupings reflecting fitness components and influences of large wood. Results of this work suggest that female coho salmon likely select breeding sites based on a wide range of habitat features linked to all four hypothesized fitness components. More specifically, model parameter estimates indicated that breeding site selection was most strongly influenced by proximity to pool-tail crests and deeper water (mean and maximum depths). Linkages between large wood and breeding site selection were less clear. Overall, our findings suggest that breeding site selection by coho salmon is influenced by a suite of fitness components in addition to the egg incubation environment, which has been the emphasis of much work in the past.

  3. Recent Eruptive History of the Tatun Volcanic Group, Northern Taiwan: Hazard-related Issues

    NASA Astrophysics Data System (ADS)

    Belousov, A.; Belousova, M.; Chen, C.

    2009-12-01

    show evidence of water/magma interaction: poor sorting, wide span of vesicularity of juvenile material, abundant xenoliths of country rocks, associated base surges, as well as ballistics of bread-crust and cauliflower type. Deposits of block-and-ash pyroclastic flows are lithic-rich and probably were formed mostly by collapses of growing domes and advancing lava flows (Merapi type). This study presents the first radiocarbon dates of various volcanoclastic deposits of the TVG, which indicate that Cising, Siaoguanyin, and possibly Huangzuei volcanoes had magmatic eruptions in the period 13,000 - 23,000 years ago. In addition, Mt. Cising had a phreatic eruption 6000 years ago. Our data have shown that TVG volcanoes should be considered as active. The results form the basis for reassessment of volcanic hazards of the area. Reference: Stevenson, R.J., Hodder, A.P.W., Briggs, R.M. (1994) Rheological estimated of rhyolite lava flows from the Okataina Volcanic Centre, New Zealand. New Zealand Journal of Geology and Geophysics, v.37: 211-221

  4. Cyanide hazards to plants and animals from gold mining and related water issues.

    PubMed

    Eisler, Ronald; Wiemeyer, Stanley N

    2004-01-01

    Cyanide extraction of gold through milling of high-grade ores and heap leaching of low-grade ores requires cycling of millions of liters of alkaline water containing high concentrations of potentially toxic sodium cyanide (NaCN), free cyanide, and metal-cyanide complexes. Some milling operations result in tailings ponds of 150 ha and larger. Heap leach operations that spray or drip cyanide onto the flattened top of the ore heap require solution processing ponds of about 1 ha in surface area. Puddles of various sizes may occur on the top of heaps, where the highest concentrations of NaCN are found. Solution recovery channels are usually constructed at the base of leach heaps, some of which may be exposed. All these cyanide-containing water bodies are hazardous to wildlife, especially migratory waterfowl and bats, if not properly managed. Accidental spills of cyanide solutions into rivers and streams have produced massive kills of fish and other aquatic biota. Freshwater fish are the most cyanide-sensitive group of aquatic organisms tested, with high mortality documented at free cyanide concentrations >20 microg/L and adverse effects on swimming and reproduction at >5 microg/L. Exclusion from cyanide solutions or reductions of cyanide concentrations to nontoxic levels are the only certain methods of protecting terrestrial vertebrate wildlife from cyanide poisoning; a variety of exclusion/cyanide reduction techniques are presented and discussed. Additional research is recommended on (1) effects of low-level, long-term, cyanide intoxication in birds and mammals by oral and inhalation routes in the vicinity of high cyanide concentrations; (2) long-term effects of low concentrations of cyanide on aquatic biota; (3) adaptive resistance to cyanide; and (4) usefulness of various biochemical indicators of cyanide poisoning. To prevent flooding in mine open pits, and to enable earth moving on a large scale, it is often necessary to withdraw groundwater and use it for

  5. Representations of the Americans with Disabilities Act Employment-Related Issues in the Wall Street Journal (1990-2008): A Feasibility Study

    ERIC Educational Resources Information Center

    Soffer, Michal; Rimmerman, Arie

    2012-01-01

    This feasibility study examines the coverage of employment-related issues related to people with disabilities in the Americans with Disabilities Act of 1990. The study is a first in a series of future studies focusing on disability issues in the international economic media. A survey of 39 newspaper articles published in the "Wall Street Journal",…

  6. An Examination of Issues Related to a Europa Subsurface Component for the JIMO Mission

    NASA Technical Reports Server (NTRS)

    Carsey, F. D.; Hecht, M. H.; Wilcox, B. H.; Behar, A. E.; Holland, P. M.

    2003-01-01

    The Galileo Europa data set served to revolutionize our view of Europa. In particular the strong evidence of a large, cold, salty Ocean beneath 5-30 km of ice has profoundly altered the significance of Europa in our thinking, especially of context of habitability in the solar system. While much remains to be learned from spacecraft observations of several sorts, there are significant questions answerable only by in-situ techniques; these relate to the formation of Europa, the nature of its ocean, and the prospects for life in its ocean, sediments, and ice. We feel that wide-ranging discussion of an in-situ subsurface mission to Europa, as part of JIMO, should proceed. The science objective of the mission is to characterize the icy shell of Europa to resolve its provenance, estimate the composition of brine of the Europa ocean, and search for evidence of Earth-like life. Probably anyone would agree that an in-situ mission to Europa would be of great value, but he or she would also immediately take the position that such a mission is utterly impractical. We take the position here of defining the least complex mission that can nonetheless justify its cost and to argue that such a mission is realistic enough that it should be seriously considered. Our mission thinking has been: 1) Soft landing. A soft lander is required on a site sufficiently flat to offer a stable platform; no further site selectivity is required. 2) Subsurface exploration. The Europa subsurface must be examined. Surficial processes on Europa arguably have exposed the upper 200 m of shell to chemical effects from the Jovian radiation belts as well as cometary infall, etc; to examine native ice we must descend below that point to, for discussion, 300 m. At that depth we argue that the ice is characteristic of ice at depth and possibly is effectively sea ice. 3) Science data. A few simple measurements at various depths and at 300 m constitute a scientifically successful mission. Measurements would

  7. An Examination of Issues Related to a Europa Subsurface Component for the JIMO Mission

    NASA Technical Reports Server (NTRS)

    Carsey, F. D.; Hecht, M. H.; Wilcox, B. H.; Behar, A. E.; Holland, P. M.

    2003-01-01

    The Galileo Europa data set served to revolutionize our view of Europa. In particular the strong evidence of a large, cold, salty Ocean beneath 5-30 km of ice has profoundly altered the significance of Europa in our thinking, especially of context of habitability in the solar system. While much remains to be learned from spacecraft observations of several sorts, there are significant questions answerable only by in-situ techniques; these relate to the formation of Europa, the nature of its ocean, and the prospects for life in its ocean, sediments, and ice. We feel that wide-ranging discussion of an in-situ subsurface mission to Europa, as part of JIMO, should proceed. The science objective of the mission is to characterize the icy shell of Europa to resolve its provenance, estimate the composition of brine of the Europa ocean, and search for evidence of Earth-like life. Probably anyone would agree that an in-situ mission to Europa would be of great value, but he or she would also immediately take the position that such a mission is utterly impractical. We take the position here of defining the least complex mission that can nonetheless justify its cost and to argue that such a mission is realistic enough that it should be seriously considered. Our mission thinking has been: 1) Soft landing. A soft lander is required on a site sufficiently flat to offer a stable platform; no further site selectivity is required. 2) Subsurface exploration. The Europa subsurface must be examined. Surficial processes on Europa arguably have exposed the upper 200 m of shell to chemical effects from the Jovian radiation belts as well as cometary infall, etc; to examine native ice we must descend below that point to, for discussion, 300 m. At that depth we argue that the ice is characteristic of ice at depth and possibly is effectively sea ice. 3) Science data. A few simple measurements at various depths and at 300 m constitute a scientifically successful mission. Measurements would

  8. THE NGA-DOE GRANT TO EXAMINE CRITICAL ISSUES RELATED TO RADIOACTIVE WASTE AND MATERIALS DISPOSITION INVOLVING DOE FACILITIES

    SciTech Connect

    Ann B. Beauchesne

    1998-09-30

    Through the National Governors' Association (NGA) project ''Critical Issues Related to Radioactive Waste and Materials Disposition Involving DOE Facilities'' NGA brings together Governors' policy advisors, state regulators, and DOE officials to examine critical issues related to the cleanup and operation of DOE nuclear weapons and research facilities. Topics explored through this project include: (1) Decisions involving disposal of mixed, low-level, and transuranic (TRU) waste and disposition of nuclear materials; (2) Decisions involving DOE budget requests and their effect on environmental cleanup and compliance at DOE facilities; (3) Strategies to treat mixed, low-level, and transuranic (TRU) waste and their effect on individual sites in the complex; (4) Changes to the FFCA site treatment plans as a result of proposals in the Department's Accelerating Cleanup: Paths to Closure plan and contractor integration analysis; (5) Interstate waste and materials shipments; and (6) Reforms to existing RCRA and CERCLA regulations/guidance to address regulatory overlap and risks posed by DOE wastes. The overarching theme of this project is to help the Department improve coordination of its major program decisions with Governors' offices and state regulators and to ensure such decisions reflect input from these key state officials and stakeholders. This report summarizes activities conducted during the quarter from June 1, 1998 through September 30, 1998, under the NGA grant. The work accomplished by the NGA project team during the past four months can be categorized as follows: (1) maintained open communication with DOE on a variety of activities and issues within the DOE environmental management complex; (2) maintained communication with NGA Federal Facilities Compliance Task Force members regarding DOE efforts to formulate a configuration for mixed low-level waste and low-level treatment and disposal, external regulation of DOE; and EM Integration activities; and (3

  9. THE NGA-DOE GRANT TO EXAMINE CRITICAL ISSUES RELATED TO RADIOACTIVE WASTE AND MATERIALS DISPOSITION INVOLVING DOE FACILITIES

    SciTech Connect

    Ann M. Beauchesne

    1999-07-30

    Through the National Governors' Association (NGA) project ''Critical Issues Related to Radioactive Waste and Materials Disposition Involving DOE Facilities'' NGA brings together Governors' policy advisors, state regulators, and DOE officials to examine critical issues related to the cleanup and operation of DOE nuclear weapons and research facilities. Topics explored through this project include: Decisions involving disposal of mixed, low-level, and transuranic (TRU) waste and disposition of nuclear materials; Decisions involving DOE budget requests and their effect on environmental cleanup and compliance at DOE facilities; Strategies to treat mixed, low-level, and transuranic (TRU) waste and their effect on individual sites in the complex; Changes to the FFCA site treatment plans as a result of proposals in the Department's Accelerating Cleanup: Paths to Closure plan and contractor integration analysis; Interstate waste and materials shipments; and Reforms to existing RCRA and CERCLA regulations/guidance to address regulatory overlap and risks posed by DOE wastes. The overarching theme of this project is to help the Department improve coordination of its major program decisions with Governors' offices and state regulators and to ensure such decisions reflect input from these key state officials and stakeholders. This report summarizes activities conducted during the quarter from May 1, 1999, through July 30, 1999, under the NGA grant. The work accomplished by the NGA project team during the past four months can be categorized as follows: maintained open communication with DOE on a variety of activities and issues within the DOE environmental management complex; maintained communication with NGA Federal Facilities Compliance Task Force members regarding DOE efforts to formulate a configuration for mixed low-level waste and low-level treatment and disposal, external regulation of DOE; and continued to facilitate interactions between the states and DOE to develop a

  10. THE NGA-DOE GRANT TO EXAMINE CRITICAL ISSUES RELATED TO RADIOACTIVE WASTE AND MATERIALS DISPOSITION INVOLVING DOE FACILITIES

    SciTech Connect

    1998-04-01

    Through the National Governors' Association (NGA) project ''Critical Issues Related to Radioactive Waste and Materials Disposition Involving DOE Facilities'' NGA brings together Governors' policy advisors, state regulators, and DOE officials to examine critical issues related to the cleanup and operation of DOE nuclear weapons and research facilities. Topics explored through this project include: Decisions involving disposal of mixed, low-level, and transuranic (TRU) waste and disposition of nuclear materials. Decisions involving DOE budget requests and their effect on environmental cleanup and compliance at DOE facilities. Strategies to treat mixed, low-level, and transuranic (TRU) waste and their effect on individual sites in the complex. Changes to the FFCA site treatment plans as a result of proposals in DOE's Accelerating Cleanup: Paths to Closure strategy and contractor integration analysis. Interstate waste and materials shipments. Reforms to existing RCRA and CERCLA regulations/guidance to address regulatory overlap and risks posed by DOE wastes. The overarching theme of this project is to help the Department improve coordination of its major program decisions with Governors' offices and state regulators and to ensure such decisions reflect input from these key state officials and stakeholders. This report summarizes activities conducted during the quarter from December 31, 1997 through April 30, 1998 under the NGA project. The work accomplished by the NGA project team during the past four months can be categorized as follows: maintained open communication with DOE on a variety of activities and issues within the DOE environmental management complex; and provided ongoing support to state-DOE interactions in preparation for the March 30-31, 1998 NGA Federal Facilities Compliance Task Force Meeting with DOE. maintained communication with NGA Federal Facilities Compliance Task Force members regarding DOE efforts to formulate a configuration for mixed low

  11. THE NGA-DOE GRANT TO EXAMINE CRITICAL ISSUES RELATED TO RADIOACTIVE WASTE AND MATERIALS DISPOSITION INVOLVING DOE FACILITIES

    SciTech Connect

    Ann M. Beauchesne

    2000-01-01

    Through the National Governors Association (NGA) project ``Critical Issues Related to Radioactive Waste and Materials Disposition Involving DOE Facilities'' NGA brings together Governors' policy advisors, state regulators, and DOE officials to examine critical issues related to the cleanup and operation of DOE nuclear weapons and research facilities. Topics explored through this project include: Decisions involving disposal of mixed, low-level, and transuranic (TRU) waste and disposition of nuclear materials; Decisions involving DOE budget requests and their effect on environmental cleanup and compliance at DOE facilities; Strategies to treat mixed, low-level, and transuranic (TRU) waste and their effect on individual sites in the complex; Changes to the FFCA site treatment plans as a result of proposals in the Department's Accelerating Cleanup: Paths to Closure plan and contractor integration analysis; Interstate waste and materials shipments; and Reforms to existing RCRA and CERCLA regulations/guidance to address regulatory overlap and risks posed by DOE wastes. The overarching theme of this project is to help the Department improve coordination of its major program decisions with Governors' offices and state regulators and to ensure such decisions reflect input from these key state officials and stakeholders. This report summarizes activities conducted during the period from October 1, 1999 through January 31, 2000, under the NGA grant. The work accomplished by the NGA project team during the past three months can be categorized as follows: maintained open communication with DOE on a variety of activities and issues within the DOE environmental management complex; convened and facilitated the October 6--8 NGA FFCA Task Force Meeting in Oak Ridge, Tennessee; maintained communication with NGA Federal Facilities Compliance Task Force members regarding DOE efforts to formulate a configuration for mixed low-level waste and low-level treatment and disposal, external

  12. THE NGA-DOE GRANT TO EXAMINE CRITICAL ISSUES RELATED TO RADIOACTIVE WASTE AND MATERIALS DISPOSITION INVOLVING DOE FACILITIES

    SciTech Connect

    1998-07-01

    Through the National Governors' Association (NGA) project ''Critical Issues Related to Radioactive Waste and Materials Disposition Involving DOE Facilities'' NGA brings together Governors' policy advisors, state regulators, and DOE officials to examine critical issues related to the cleanup and operation of DOE nuclear weapons and research facilities. Topics explored through this project include: Decisions involving disposal of mixed, low-level, and transuranic (TRU) waste and disposition of nuclear materials. Decisions involving DOE budget requests and their effect on environmental cleanup and compliance at DOE facilities. Strategies to treat mixed, low-level, and transuranic (TRU) waste and their effect on individual sites in the complex. Changes to the FFCA site treatment plans as a result of proposals in DOE's Accelerating Cleanup: Paths to Closure strategy and contractor integration analysis. Interstate waste and materials shipments. Reforms to existing RCRA and CERCLA regulations/guidance to address regulatory overlap and risks posed by DOE wastes. The overarching theme of this project is to help the Department improve coordination of its major program decisions with Governors' offices and state regulators and to ensure such decisions reflect input from these key state officials and stakeholders. This report summarizes activities conducted during the quarter from April 30, 1998 through June 30, 1998 under the NGA project. The work accomplished by the NGA project team during the past four months can be categorized as follows: maintained open communication with DOE on a variety of activities and issues within the DOE environmental management complex; and provided ongoing support to state-DOE interactions. maintained communication with NGA Federal Facilities Compliance Task Force members regarding DOE efforts to formulate a configuration for mixed low-level waste and low-level treatment and disposal, DOE's Environmental Management Budget, and DOE's proposed

  13. THE NGA-DOE GRANT TO EXAMINE CRITICAL ISSUES RELATED TO RADIOACTIVE WASTE AND MATERIALS DISPOSITION INVOLVING DOE FACILITIES

    SciTech Connect

    Ann M. Beauchesne

    1999-04-30

    Through the National Governors' Association (NGA) project ''Critical Issues Related to Radioactive Waste and Materials Disposition Involving DOE Facilities'' NGA brings together Governors' policy advisors, state regulators, and DOE officials to examine critical issues related to the cleanup and operation of DOE nuclear weapons and research facilities. Topics explored through this project include: Decisions involving disposal of mixed, low-level, and transuranic (TRU) waste and disposition of nuclear materials; Decisions involving DOE budget requests and their effect on environmental cleanup and compliance at DOE facilities; Strategies to treat mixed, low-level, and transuranic (TRU) waste and their effect on individual sites in the complex; Changes to the FFCA site treatment plans as a result of proposals in the Department's Accelerating Cleanup: Paths to Closure plan and contractor integration analysis; Interstate waste and materials shipments; and Reforms to existing RCRA and CERCLA regulations/guidance to address regulatory overlap and risks posed by DOE wastes. The overarching theme of this project is to help the Department improve coordination of its major program decisions with Governors' offices and state regulators and to ensure such decisions reflect input from these key state officials and stakeholders. This report summarizes activities conducted during the quarter from February 1, 1999, through April 30, 1999, under the NGA grant. The work accomplished by the NGA project team during the past four months can be categorized as follows: maintained open communication with DOE on a variety of activities and issues within the DOE environmental management complex; maintained communication with NGA Federal Facilities Compliance Task Force members regarding DOE efforts to formulate a configuration for mixed low-level waste and low-level treatment and disposal, external regulation of DOE; and EM Integration activities; and continued to serve as a liaison between

  14. THE NGA-DOE GRANT TO EXAMINE CRITICAL ISSUES RELATED TO RADIOACTIVE WASTE AND MATERIALS DISPOSITION INVOLVING DOE FACILITIES

    SciTech Connect

    1998-01-01

    Through the National Governors' Association (NGA) project ''Critical Issues Related to Radioactive Waste and Materials Disposition Involving DOE Facilities'' NGA brings together Governors' policy advisors, state regulators, and DOE officials to examine critical issues related to the cleanup and operation of DOE nuclear weapons and research facilities. Topics explored through this project include: Decisions involving disposal of mixed, low-level, and transuranic (TRU) waste and disposition of nuclear materials. Decisions involving DOE budget requests and their effect on environmental cleanup and compliance at DOE facilities. Strategies to treat mixed, low-level, and transuranic (TRU) waste and their effect on individual sites in the complex. Changes to the FFCA site treatment plans as a result of proposals in the EM 2006 cleanup plans and contractor integration analysis. Interstate waste and materials shipments. Reforms to existing RCRA and CERCLA regulations/guidance to address regulatory overlap and risks posed by DOE wastes. The overarching theme of this project is to help the Department improve coordination of its major program decisions with Governors' offices and state regulators and to ensure such decisions reflect input from these key state officials and stakeholders. This report summarizes activities conducted during the quarter from October 1, 1997 through December 31, 1997, under the NGA project. The work accomplished by the NGA project team during the past four months can be categorized as follows: maintained open communication with DOE on a variety of activities and issues within the DOE environmental management complex; and maintained communication with NGA Federal Facilities Compliance Task Force members regarding DOE efforts to formulate a configuration for mixed low-level waste and low-level treatment and disposal, DOE activities in the area of the Hazardous Waste Identification Rule, and DOE's proposed National Dialogue.

  15. THE NGA-DOE GRANT TO EXAMINE CRITICAL ISSUES RELATED TO RADIOACTIVE WASTE AND MATERIALS DISPOSITION INVOLVING DOE FACILITIES

    SciTech Connect

    Ann M. Beauchesne

    1999-01-31

    Through the National Governors' Association (NGA) project ''Critical Issues Related to Radioactive Waste and Materials Disposition Involving DOE Facilities'' NGA brings together Governors' policy advisors, state regulators, and DOE officials to examine critical issues related to the cleanup and operation of DOE nuclear weapons and research facilities. Topics explored through this project include: (1) Decisions involving disposal of mixed, low-level, and transuranic (TRU) waste and disposition of nuclear materials; (2) Decisions involving DOE budget requests and their effect on environmental cleanup and compliance at DOE facilities; (3) Strategies to treat mixed, low-level, and transuranic (TRU) waste and their effect on individual sites in the complex; (4) Changes to the FFCA site treatment plans as a result of proposals in the Department's Accelerating Cleanup: Paths to Closure plan and contractor integration analysis; (5) Interstate waste and materials shipments; and (6) Reforms to existing RCRA and CERCLA regulations/guidance to address regulatory overlap and risks posed by DOE wastes. The overarching theme of this project is to help the Department improve coordination of its major program decisions with Governors' offices and state regulators and to ensure such decisions reflect input from these key state officials and stakeholders. This report summarizes activities conducted during the quarter from October 1, 1998 through January 31, 1999, under the NGA grant. The work accomplished by the NGA project team during the past four months can be categorized as follows: (1) maintained open communication with DOE on a variety of activities and issues within the DOE environmental management complex; (2) maintained communication with NGA Federal Facilities Compliance Task Force members regarding DOE efforts to formulate a configuration for mixed low-level waste and low-level treatment and disposal, external regulation of DOE; and EM Integration activities; and (3

  16. THE NGA-DOE GRANT TO EXAMINE CRITICAL ISSUES RELATED TO RADIOACTIVE WASTE AND MATERIALS DISPOSITION INVOLVING DOE FACILITIES

    SciTech Connect

    Ethan W. Brown

    2001-09-01

    Through the National Governors' Association (NGA) project ''Critical Issues Related to Radioactive Waste and Materials Disposition Involving DOE Facilities'' NGA brings together Governors' policy advisors, state regulators, and DOE officials to examine critical issues related to the cleanup and operation of DOE nuclear weapons and research facilities. Topics explored through this project include: Decisions involving disposal of mixed, low-level, and transuranic (TRU) waste and disposition of nuclear materials. Decisions involving DOE budget requests and their effect on environmental cleanup and compliance at DOE facilities. Strategies to treat mixed, low-level, and transuranic (TRU) waste and their effect on individual sites in the complex. Changes to the FFCA site treatment plans as a result of proposals in the Department's Accelerating Cleanup: Paths to Closure plan and contractor integration analysis. Interstate waste and materials shipments. Reforms to existing RCRA and CERCLA regulations/guidance to address regulatory overlap and risks posed by DOE wastes. The overarching theme of this project is to help the Department improve coordination of its major program decisions with Governors' offices and state regulators and to ensure such decisions reflect input from these key state officials and stakeholders. This report summarizes activities conducted during the period from April 1, 2001 through June 30, 2001, under the NGA grant.

  17. Software Archive Related Issues

    NASA Technical Reports Server (NTRS)

    Angelini, Lorella

    2008-01-01

    With the archive opening of the major X-ray and Gamma ray missions, the school is intended to provide information on the resource available in the data archive and the public software. This talk reviews the archive content, the data format for the major active missions Chandra, XMM-Newton, Swift, RXTE, Integral and Suzaku and the available software for each of these missions. It will explain the FITS format in general and the specific layout for the most popular mission, explaining the role of keywords and how they fit in the multimission standard approach embrace by the High Energy Community. Specifically, it reviews : the difference data levels and the difference software applicable; the popular/standard method of analysis for high level products such as spectra, timing and images; the role of calibration in the multi mission approach; how to navigate the archive query databases. It will present also how the school is organized and how the information provided will be relevant to each of the afternoon science projects that will be proposed to the students and led by a project leader

  18. Issues for researchers to consider when using health-related quality of life outcomes in cancer research.

    PubMed

    McCabe, C; Cronin, P

    2011-09-01

    Maintaining quality of life for patients with cancer is a key factor when developing services related to diagnosis, treatment, recovery and/or terminal care. This paper questions whether health-related quality of life (HRQoL) is an appropriate measure of quality of life given that it does not assess factors reported by patients as being most influential, e.g. contact with family and social/cultural interaction. Ambiguity related to the definition and understanding of anxiety, depression and distress as outcomes commonly used by clinicians and researchers when measuring HRQoL in cancer research is also addressed by this paper. The findings of many cancer studies are interpreted and presented on very broad and poorly defined concepts thus preventing the development of a coherent and true understanding of how these outcomes influence quality of life for cancer patients. The authors of this paper conclude that the documentation and clear explanation of the concepts underpinning the choice of instrument and study design is essential but also the inclusion of outcomes related to social support and interaction would provide a more accurate account of quality of life issues in cancer research. PMID:21029221

  19. Additive effects of affective arousal and top-down attention on the event-related brain responses to human bodies.

    PubMed

    Hietanen, Jari K; Kirjavainen, Ilkka; Nummenmaa, Lauri

    2014-12-01

    The early visual event-related 'N170 response' is sensitive to human body configuration and it is enhanced to nude versus clothed bodies. We tested whether the N170 response as well as later EPN and P3/LPP responses to nude bodies reflect the effect of increased arousal elicited by these stimuli, or top-down allocation of object-based attention to the nude bodies. Participants saw pictures of clothed and nude bodies and faces. In each block, participants were asked to direct their attention towards stimuli from a specified target category while ignoring others. Object-based attention did not modulate the N170 amplitudes towards attended stimuli; instead N170 response was larger to nude bodies compared to stimuli from other categories. Top-down attention and affective arousal had additive effects on the EPN and P3/LPP responses reflecting later processing stages. We conclude that nude human bodies have a privileged status in the visual processing system due to the affective arousal they trigger. PMID:25224182

  20. Are delta-aminolevulinate dehydratase inhibition and metal concentrations additional factors for the age-related cognitive decline?

    PubMed

    Baierle, Marília; Charão, Mariele F; Göethel, Gabriela; Barth, Anelise; Fracasso, Rafael; Bubols, Guilherme; Sauer, Elisa; Campanharo, Sarah C; Rocha, Rafael C C; Saint'Pierre, Tatiana D; Bordignon, Suelen; Zibetti, Murilo; Trentini, Clarissa M; Avila, Daiana S; Gioda, Adriana; Garcia, Solange C

    2014-01-01

    Aging is often accompanied by cognitive impairments and influenced by oxidative status and chemical imbalances. Thus, this study was conducted to examine whether age-related cognitive deficit is associated with oxidative damage, especially with inhibition of the enzyme delta-aminolevulinate dehydratase (ALA-D), as well as to verify the influence of some metals in the enzyme activity and cognitive performance. Blood ALA-D activity, essential (Fe, Zn, Cu, Se) and non-essential metals (Pb, Cd, Hg, As, Cr, Ni, V) were measured in 50 elderly and 20 healthy young subjects. Cognitive function was assessed by tests from Consortium to Establish a Registry for Alzheimer's Disease (CERAD) battery and other. The elderly group presented decreased ALA-D activity compared to the young group. The index of ALA-D reactivation was similar to both study groups, but negatively associated with metals. The mean levels of essential metals were within the reference values, while the most toxic metals were above them in both groups. Cognitive function impairments were observed in elderly group and were associated with decreased ALA-D activity, with lower levels of Se and higher levels of toxic metals (Hg and V). Results suggest that the reduced ALA-D activity in elderly can be an additional factor involved in cognitive decline, since its inhibition throughout life could lead to accumulation of the neurotoxic compound ALA. Toxic metals were found to contribute to cognitive decline and also to influence ALA-D reactivation. PMID:25329536

  1. Review of Technical Issues Related to Predicting Isotopic Compositions and Source Terms for High-Burnup LWR Fuel

    SciTech Connect

    Gauld, I. C.; Parks, C. V.

    2000-12-11

    This report has been prepared to review the technical issues important to the prediction of isotopic compositions and source terms for high-burnup, light-water-reactor (LWR) fuel as utilized in the licensing of spent fuel transport and storage systems. The current trend towards higher initial 235U enrichments, more complex assembly designs, and more efficient fuel management schemes has resulted in higher spent fuel burnups than seen in the past. This trend has led to a situation where high-burnup assemblies from operating LWRs now extend beyond the area where available experimental data can be used to validate the computational methods employed to calculate spent fuel inventories and source terms. This report provides a brief review of currently available validation data, including isotopic assays, decay heat measurements, and shielded dose-rate measurements. Potential new sources of experimental data available in the near term are identified. A review of the background issues important to isotopic predictions and some of the perceived technical challenges that high-burnup fuel presents to the current computational methods are discussed. Based on the review, the phenomena that need to be investigated further and the technical issues that require resolution are presented. The methods and data development that may be required to address the possible shortcomings of physics and depletion methods in the high-burnup and high-enrichment regime are also discussed. Finally, a sensitivity analysis methodology is presented. This methodology is currently being investigated at the Oak Ridge National Laboratory as a computational tool to better understand the changing relative significance of the underlying nuclear data in the different enrichment and burnup regimes and to identify the processes that are dominant in the high-burnup regime. The potential application of the sensitivity analysis methodology to help establish a range of applicability for experimental

  2. Women living with disabilities and their experiences and issues related to the context and complexities of leaving abusive situations.

    PubMed

    Yoshida, Karen K; Odette, Fran; Hardie, Susan; Willis, Heather; Bunch, Mary

    2009-01-01

    The health of women with disabilities, like other women, is affected by experiences of violence and abuse. However, the experiences of women living with disabilities is less well known and an important issue for rehabilitation professionals. In this paper we focus on presenting women's knowledge and experiences of violence and abuse regarding where abuse takes place, the forms of abuse; and the complexities associated with 'taking action'. Women participants for this study had to be: 18 years of age or older; a Canadian citizen; able to participate in English; self-defined with a disability; and, be living in an urban area of Canada. Data presented is based on an innovative community-academic research study in which focus groups discussions using electronic technology (i.e. blackboard and chat rooms) were conducted with women living with disabilities across the country on important health issues. Participants' recommendations are also presented. Discussion of the findings focus on policy and practice implications related to dedicated resources, access to information and training initiatives for rehabilitation professionals and women themselves. PMID:19479561

  3. Perceptions of, and reactions to, environmental heat: a brief note on issues of concern in relation to occupational health

    PubMed Central

    Hollowell, Delia Rizpah

    2010-01-01

    Average temperatures around the world are already increasing, and climate change projections suggest that global mean temperatures will continue to rise. As the effects, and projected effects, of climate change are becoming clearer, it is more apparent that the health effects of heat exposure will need further investigation. The risks associated with heat exposure are especially relevant to understandings of occupational health for people involved in labouring or agricultural work in low-income countries. This review is a partial look at the ways in which issues surrounding heat exposure and occupational health have been treated in some of the available literature. This literature focuses on military-related medical understandings of heat exposure as well as heat exposure in working environments. The ways that these issues have been treated throughout the literature reflect the ways in which technologies of observation are intertwined with social attitudes. The effects of heat on the health of working people, as well as identification of risk groups, will require further research in order to promote prophylactic measures as well as to add to understandings of the actual and potential consequences of climatic change. PMID:21191480

  4. Approach to ecological assessment of power-plant-intake (316b) related issues: the Prairie Island case

    SciTech Connect

    Adams, S.M.; Vaughan, D.S.; Hildebrand, S.G.; Kumar, K.D.

    1981-04-01

    Assessment approaches and strategies useful in addressing important issues in section 316(b) of the 1972 Federal Water Pollution Control Act are illustrated in this report through the analysis and evaluation of the Prairie Island Nuclear Station 316(b) data base. The main issues in 316(b) demonstrations, cooling water intake operation and location, involve determining the impacts of entrainment and impingement. Entrainment impacts were addressed by applying the equivalent adult approach and correcting for inherent biases and by determining the through-plant survival of zooplankton. An assessment of impingement impacts was made by comparing for each of various species the number of fish impinged to estimates of population size. Densities of plankton and fish were compared between the intake area and an alternate area to determine if the location of the present intake minimizes impacts. No definitive conclusion relative to the best location of the intake could be made because of high year to year variability in the data and the differential dominance of trophic groups between areas.

  5. Differences in Moral Judgment on Animal and Human Ethics Issues between University Students in Animal-Related, Human Medical and Arts Programs

    PubMed Central

    Verrinder, Joy M.; Ostini, Remo; Phillips, Clive J. C.

    2016-01-01

    Moral judgment in relation to animal ethics issues has rarely been investigated. Among the research that has been conducted, studies of veterinary students have shown greater use of reasoning based on universal principles for animal than human ethics issues. This study aimed to identify if this was unique to students of veterinary and other animal-related professions. The moral reasoning of first year students of veterinary medicine, veterinary technology, and production animal science was compared with that of students in non-animal related disciplines of human medicine and arts. All students (n = 531) completed a moral reasoning test, the VetDIT, with animal and human scenarios. When compared with reasoning on human ethics issues, the combined group of students evaluating animal ethics issues showed higher levels of Universal Principles reasoning, lower levels of Personal Interest reasoning and similar levels of Maintaining Norms reasoning. Arts students showed more personal interest reasoning than students in most animal-related programs on both animal and human ethics issues, and less norms-based reasoning on animal ethics issues. Medical students showed more norms-based reasoning on animal ethics issues than all of the animal-related groups. There were no differences in principled reasoning on animal ethics issues between program groups. This has implications for animal-related professions and education programs showing that students’ preference for principled reasoning on animal ethics issues is not unique to animal-related disciplines, and highlighting the need to develop student (and professional) capacity to apply principled reasoning to address ethics issues in animal industries to reduce the risk of moral distress. PMID:26934582

  6. Differences in Moral Judgment on Animal and Human Ethics Issues between University Students in Animal-Related, Human Medical and Arts Programs.

    PubMed

    Verrinder, Joy M; Ostini, Remo; Phillips, Clive J C

    2016-01-01

    Moral judgment in relation to animal ethics issues has rarely been investigated. Among the research that has been conducted, studies of veterinary students have shown greater use of reasoning based on universal principles for animal than human ethics issues. This study aimed to identify if this was unique to students of veterinary and other animal-related professions. The moral reasoning of first year students of veterinary medicine, veterinary technology, and production animal science was compared with that of students in non-animal related disciplines of human medicine and arts. All students (n = 531) completed a moral reasoning test, the VetDIT, with animal and human scenarios. When compared with reasoning on human ethics issues, the combined group of students evaluating animal ethics issues showed higher levels of Universal Principles reasoning, lower levels of Personal Interest reasoning and similar levels of Maintaining Norms reasoning. Arts students showed more personal interest reasoning than students in most animal-related programs on both animal and human ethics issues, and less norms-based reasoning on animal ethics issues. Medical students showed more norms-based reasoning on animal ethics issues than all of the animal-related groups. There were no differences in principled reasoning on animal ethics issues between program groups. This has implications for animal-related professions and education programs showing that students' preference for principled reasoning on animal ethics issues is not unique to animal-related disciplines, and highlighting the need to develop student (and professional) capacity to apply principled reasoning to address ethics issues in animal industries to reduce the risk of moral distress. PMID:26934582

  7. Designing health care environments: Part I. Basic concepts, principles, and issues related to evidence-based design.

    PubMed

    Cesario, Sandra K

    2009-06-01

    A 2001 Institute of Medicine report captured the nation's attention regarding the dangers that can result from the health care environment. This report, fueled by the need for new facilities to be constructed, led to an explosion of research that now links the physical structure and design of health care facilities to the health and well-being of patients, nurses, other health care workers, and visitors. Continuing nursing education that highlights the importance of evidence-based design has been associated with measurable improvement in health care facilities' clinical outcomes, economic performance, employee productivity, customer satisfaction, and cultural congruency. Three major categories of outcomes can be impacted by evidence-based design: stress reduction, safety, and overall health care quality and ecology. In this article, Part I of a two-part series, the basic concepts, principles, and issues related to evidence-based design are introduced. Part II will describe continuing education programs available for nurses. PMID:19639918

  8. The role of time and time perspective in age-related processes: Introduction to the special issue.

    PubMed

    Fung, Helene H; Isaacowitz, Derek M

    2016-09-01

    There currently appears to be a general consensus on the relationship between time perspective and aging, such that (a) future time is perceived as more limited with age and (b) older people are more present-focused and less future-focused than younger people. At the same time, there are debates about whether these age differences are positively related to well-being and to what extent there are boundary conditions beyond which these age differences would cease to occur. The 8 manuscripts included in this Special Issue attempt to shed light on these debates. In doing so, they refine the dominant theoretical perspective on the topic-socioemotional selectivity theory-and introduce new theoretical perspectives. New measures and methodologies for studying time perspective and aging are also discussed. (PsycINFO Database Record PMID:27599019

  9. 77 FR 24628 - World Trade Center Health Program Requirements for the Addition of New WTC-Related Health Conditions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... on the notice of proposed rulemaking published in the Federal Register on July 1, 2011 (76 FR 38938... Health Program within HHS. HHS issued an interim final rule on July 1, 2011 (76 FR 38914), which codified... rule on July 1, 2011 (76 FR 38914). Comment: HHS received two comments requesting that the...

  10. Some legal, social, and ethical issues related to the genetic testing revolution, as exemplified in the long QT syndrome.

    PubMed

    Liebman, J

    2001-01-01

    Molecular Biology is revolutionizing medicine. There are a number of conditions, particularly exemplified by the long QT syndrome, where there is no structural abnormality but where a subset of patients is prone to sudden death. The issues of appropriate care are very complex, because there is tremendous overlap between patients with prolongation of the QT who remain asymptomatic and those with prolongation who are very symptomatic. Furthermore, even those who are prone to have one of the abnormal genes, may be asymptomatic. A large literature has developed, from both legal and ethical aspects, related to the fact that in genetic disease per se, not only is the person at risk, but so are many members of his or her family. A large literature has also developed as to which should be prime, the patient's privacy or the responsibility to make sure the entire family is knowledgeable and perhaps tested. At the present moment our care is based upon the fact that the precise identification of the gene is not yet available on a routine basis. This of course, may soon change. But we will still have difficult decisions to make. Obviously, we have a responsibility as physicians to be as precise as our discipline allows, but we have a responsibility to be flexible. Relief of anxiety, as an example, has to be a prime issue. This is certainly the case now when any information related to infants with potential sudden death is still incomplete. We must not approach the care of the patient in such a way that protection of the physician may interfere with appropriate care. The discussion necessarily includes a variety of aspects. PMID:11781954

  11. Unresolved or Contradictory Issues About Management of Patients With Patent Foramen Ovale and Previous Cryptogenic Stroke: Additional Randomized Controlled Trials Are Eagerly Awaited

    PubMed Central

    De Vecchis, Renato; Baldi, Cesare

    2016-01-01

    Stating a well-codified and widely accepted therapeutic conduct for patients with patent foramen ovale (PFO) and previous cryptogenic stroke is made difficult and somewhat controversial by several issues remained unresolved so far. In this short review, some aspects of the possible role played by the PFO in the pathogenesis of cryptogenic stroke are succinctly analyzed. First, some aspects of cardiovascular anatomy of the human fetus and the adult are outlined. Subsequently, the three randomized controlled trials (RCTs) that have been accomplished so far to compare the implant of a transeptal occluding device with a simple medical therapy in patients with PFO and history of cryptogenic stroke are briefly examined. These RCTs, when assessed using the “intention to treat” method, do not show a greater protective effect of therapy with transeptal device as regards the recurrences of stroke. Afterwards, there is a brief presentation of the findings of several meta-analyses that have been derived from the three above mentioned RCTs, whose results are strikingly discordant with each other. In fact, some of them come to the conclusion that the transcatheter closure of PFO does not offer significant advantages compared to antithrombotic therapy for the secondary prevention of cryptogenic stroke, while others based on subgroup analyses argue that the transcatheter closure of PFO with Amplatzer device, differently from the one performed using the STARFlex device, would be associated with significantly lower incidence of cerebrovascular events compared with medical therapy alone. Finally, the authors argue the need to adhere to the current scientific guidelines. They substantially deny an alleged superior efficacy of transcatheter PFO occlusion compared to medical therapy with antithrombotic agents (anticoagulants or antiplatelet agents), except for selected cases of patients with documented PFO and concomitant clinical-instrumental picture of deep venous thrombosis. PMID

  12. Unresolved or Contradictory Issues About Management of Patients With Patent Foramen Ovale and Previous Cryptogenic Stroke: Additional Randomized Controlled Trials Are Eagerly Awaited.

    PubMed

    De Vecchis, Renato; Baldi, Cesare

    2016-05-01

    Stating a well-codified and widely accepted therapeutic conduct for patients with patent foramen ovale (PFO) and previous cryptogenic stroke is made difficult and somewhat controversial by several issues remained unresolved so far. In this short review, some aspects of the possible role played by the PFO in the pathogenesis of cryptogenic stroke are succinctly analyzed. First, some aspects of cardiovascular anatomy of the human fetus and the adult are outlined. Subsequently, the three randomized controlled trials (RCTs) that have been accomplished so far to compare the implant of a transeptal occluding device with a simple medical therapy in patients with PFO and history of cryptogenic stroke are briefly examined. These RCTs, when assessed using the "intention to treat" method, do not show a greater protective effect of therapy with transeptal device as regards the recurrences of stroke. Afterwards, there is a brief presentation of the findings of several meta-analyses that have been derived from the three above mentioned RCTs, whose results are strikingly discordant with each other. In fact, some of them come to the conclusion that the transcatheter closure of PFO does not offer significant advantages compared to antithrombotic therapy for the secondary prevention of cryptogenic stroke, while others based on subgroup analyses argue that the transcatheter closure of PFO with Amplatzer device, differently from the one performed using the STARFlex device, would be associated with significantly lower incidence of cerebrovascular events compared with medical therapy alone. Finally, the authors argue the need to adhere to the current scientific guidelines. They substantially deny an alleged superior efficacy of transcatheter PFO occlusion compared to medical therapy with antithrombotic agents (anticoagulants or antiplatelet agents), except for selected cases of patients with documented PFO and concomitant clinical-instrumental picture of deep venous thrombosis. PMID

  13. A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease

    PubMed Central

    Holmans, Peter; Moskvina, Valentina; Jones, Lesley; Sharma, Manu; Vedernikov, Alexey; Buchel, Finja; Sadd, Mohamad; Bras, Jose M.; Bettella, Francesco; Nicolaou, Nayia; Simón-Sánchez, Javier; Mittag, Florian; Gibbs, J. Raphael; Schulte, Claudia; Durr, Alexandra; Guerreiro, Rita; Hernandez, Dena; Brice, Alexis; Stefánsson, Hreinn; Majamaa, Kari; Gasser, Thomas; Heutink, Peter; Wood, Nicholas W.; Martinez, Maria; Singleton, Andrew B.; Nalls, Michael A.; Hardy, John; Morris, Huw R.; Williams, Nigel M.; Arepalli, Sampath; Barker, Roger; Barrett, Jeffrey; Ben-Shlomo, Yoav; Berendse, Henk W.; Berg, Daniela; Bhatia, Kailash; de Bie, Rob M.A.; Biffi, Alessandro; Bloem, Bas; Brice, Alexis; Bochdanovits, Zoltan; Bonin, Michael; Bras, Jose M.; Brockmann, Kathrin; Brooks, Janet; Burn, David J.; Charlesworth, Gavin; Chen, Honglei; Chinnery, Patrick F.; Chong, Sean; Clarke, Carl E.; Cookson, Mark R.; Cooper, Jonathan M.; Corvol, Jen-Christophe; Counsell, Carl; Damier, Philippe; Dartigues, Jean Francois; Deloukas, Panagiotis; Deuschl, Günther; Dexter, David T.; van Dijk, Karin D.; Dillman, Allissa; Durif, Frank; Durr, Alexandra; Edkins, Sarah; Evans, Jonathan R.; Foltynie, Thomas; Gao, Jianjun; Gardner, Michelle; Gasser, Thomas; Gibbs, J. Raphael; Goate, Alison; Gray, Emma; Guerreiro, Rita; Gústafsson, Ómar; Hardy, John; Harris, Clare; Hernandez, Dena G.; Heutink, Peter; van Hilten, Jacobus J.; Hofman, Albert; Hollenbeck, Albert; Holmans, Peter; Holton, Janice; Hu, Michele; Huber, Heiko; Hudson, Gavin; Hunt, Sarah E.; Huttenlocher, Johanna; Illig, Thomas; Langford, Cordelia; Lees, Andrew; Lesage, Suzanne; Lichtner, Peter; Limousin, Patricia; Lopez, Grisel; Lorenz, Delia; Martinez, Maria; McNeill, Alisdair; Moorby, Catriona; Moore, Matthew; Morris, Huw; Morrison, Karen E.; Moskvina, Valentina; Mudanohwo, Ese; Nalls, Michael A.; Pearson, Justin; Perlmutter, Joel S.; Pétursson, Hjörvar; Plagnol, Vincent; Pollak, Pierre; Post, Bart; Potter, Simon; Ravina, Bernard; Revesz, Tamas; Riess, Olaf; Rivadeneira, Fernando; Rizzu, Patrizia; Ryten, Mina; Saad, Mohamad; Sawcer, Stephen; Schapira, Anthony; Scheffer, Hans; Sharma, Manu; Shaw, Karen; Sheerin, Una-Marie; Shoulson, Ira; Schulte, Claudia; Sidransky, Ellen; Simón-Sánchez, Javier; Singleton, Andrew B.; Smith, Colin; Stefánsson, Hreinn; Stefánsson, Kári; Steinberg, Stacy; Stockton, Joanna D.; Sveinbjornsdottir, Sigurlaug; Talbot, Kevin; Tanner, Carlie M.; Tashakkori-Ghanbaria, Avazeh; Tison, François; Trabzuni, Daniah; Traynor, Bryan J.; Uitterlinden, André G.; Velseboer, Daan; Vidailhet, Marie; Walker, Robert; van de Warrenburg, Bart; Wickremaratchi, Mirdhu; Williams, Nigel; Williams-Gray, Caroline H.; Winder-Rhodes, Sophie; Wood, Nicholas

    2013-01-01

    Parkinson's disease (PD) is the second most common neurodegenerative disease affecting 1–2% in people >60 and 3–4% in people >80. Genome-wide association (GWA) studies have now implicated significant evidence for association in at least 18 genomic regions. We have studied a large PD-meta analysis and identified a significant excess of SNPs (P < 1 × 10−16) that are associated with PD but fall short of the genome-wide significance threshold. This result was independent of variants at the 18 previously implicated regions and implies the presence of additional polygenic risk alleles. To understand how these loci increase risk of PD, we applied a pathway-based analysis, testing for biological functions that were significantly enriched for genes containing variants associated with PD. Analysing two independent GWA studies, we identified that both had a significant excess in the number of functional categories enriched for PD-associated genes (minimum P = 0.014 and P = 0.006, respectively). Moreover, 58 categories were significantly enriched for associated genes in both GWA studies (P < 0.001), implicating genes involved in the ‘regulation of leucocyte/lymphocyte activity’ and also ‘cytokine-mediated signalling’ as conferring an increased susceptibility to PD. These results were unaltered by the exclusion of all 178 genes that were present at the 18 genomic regions previously reported to be strongly associated with PD (including the HLA locus). Our findings, therefore, provide independent support to the strong association signal at the HLA locus and imply that the immune-related genetic susceptibility to PD is likely to be more widespread in the genome than previously appreciated. PMID:23223016

  14. Knowledge and Attitudes of French and Israeli 12th Graders in Agricultural or Rural Secondary Schools about Water and Irrigation Related Issues.

    ERIC Educational Resources Information Center

    Dreyfus, Amos; Jacobi, Daniel; Mazouz, Yossef; Lacroix, Jean-Louis

    1997-01-01

    Knowledge and attitudes of 154 Israeli 12th graders, expected to be very aware of water-related agricultural issues, and of 447 French 12th graders were compared, focusing on possibilities of change of existing situations. Israeli students put much greater emphasis on the role of scientific knowledge and the authorities in water control issues.…

  15. A People Extra: North Dakota and United States Situational Issues Related to and Influences upon--Families (Single Persons, Single Parents, Parent-Child, Married).

    ERIC Educational Resources Information Center

    North Dakota Univ., Fargo. Dept. of Agriculture and Applied Science.

    Situational issues related to families and influences upon families in North Dakota and the United States are briefly outlined in these fact sheets. Contents specifically concern (1) outbound migration from North Dakota and transition of rural families from farming; (2) suicide in North Dakota and the nation; (3) child care issues, such as child…

  16. Food additives.

    PubMed

    Berglund, F

    1978-01-01

    The use of additives to food fulfils many purposes, as shown by the index issued by the Codex Committee on Food Additives: Acids, bases and salts; Preservatives, Antioxidants and antioxidant synergists; Anticaking agents; Colours; Emulfifiers; Thickening agents; Flour-treatment agents; Extraction solvents; Carrier solvents; Flavours (synthetic); Flavour enhancers; Non-nutritive sweeteners; Processing aids; Enzyme preparations. Many additives occur naturally in foods, but this does not exclude toxicity at higher levels. Some food additives are nutrients, or even essential nutritents, e.g. NaCl. Examples are known of food additives causing toxicity in man even when used according to regulations, e.g. cobalt in beer. In other instances, poisoning has been due to carry-over, e.g. by nitrate in cheese whey - when used for artificial feed for infants. Poisonings also occur as the result of the permitted substance being added at too high levels, by accident or carelessness, e.g. nitrite in fish. Finally, there are examples of hypersensitivity to food additives, e.g. to tartrazine and other food colours. The toxicological evaluation, based on animal feeding studies, may be complicated by impurities, e.g. orthotoluene-sulfonamide in saccharin; by transformation or disappearance of the additive in food processing in storage, e.g. bisulfite in raisins; by reaction products with food constituents, e.g. formation of ethylurethane from diethyl pyrocarbonate; by metabolic transformation products, e.g. formation in the gut of cyclohexylamine from cyclamate. Metabolic end products may differ in experimental animals and in man: guanylic acid and inosinic acid are metabolized to allantoin in the rat but to uric acid in man. The magnitude of the safety margin in man of the Acceptable Daily Intake (ADI) is not identical to the "safety factor" used when calculating the ADI. The symptoms of Chinese Restaurant Syndrome, although not hazardous, furthermore illustrate that the whole ADI

  17. Estimates of U.S. Commercial Building Electricity Intensity Trends: Issues Related to End-Use and Supply Surveys

    SciTech Connect

    Belzer, David B.

    2004-09-04

    This report examines measurement issues related to the amount of electricity used by the commercial sector in the U.S. and the implications for historical trends of commercial building electricity intensity (kWh/sq. ft. of floor space). The report compares two (Energy Information Administration) sources of data related to commercial buildings: the Commercial Building Energy Consumption Survey (CBECS) and the reporting by utilities of sales to commercial customers (survey Form-861). Over past two decades these sources suggest significantly different trend rates of growth of electricity intensity, with the supply (utility)-based estimate growing much faster than that based only upon the CBECS. The report undertakes various data adjustments in an attempt to rationalize the differences between these two sources. These adjustments deal with: 1) periodic reclassifications of industrial vs. commercial electricity usage at the state level and 2) the amount of electricity used by non-enclosed equipment (non-building use) that is classified as commercial electricity sales. In part, after applying these adjustments, there is a good correspondence between the two sources over the the past four CBECS (beginning with 1992). However, as yet, there is no satisfactory explanation of the differences between the two sources for longer periods that include the 1980s.

  18. Attitudes toward Euthanasia and Related Issues among Physicians and Patients in a Multi-cultural Society of Malaysia

    PubMed Central

    Rathor, Mohammad Yousuf; Abdul Rani, Mohammad Fauzi; Shahar, Mohammad Arif; Jamalludin, A. Rehman; Che Abdullah, Shahrin Tarmizi Bin; Omar, Ahmad Marzuki Bin; Mohamad Shah, Azarisman Shah Bin

    2014-01-01

    Introduction: Due to globalization and changes in the health care delivery system, there has been a gradual change in the attitude of the medical community as well as the lay public toward greater acceptance of euthanasia as an option for terminally ill and dying patients. Physicians in developing countries come across situations where such issues are raised with increasing frequency. As euthanasia has gained world-wide prominence, the objectives of our study therefore were to explore the attitude of physicians and chronically ill patients toward euthanasia and related issues. Concomitantly, we wanted to ascertain the frequency of requests for assistance in active euthanasia. Materials and Methods: Questionnaire based survey among consenting patients and physicians. Results: The majority of our physicians and patients did not support active euthanasia or physician-assisted suicide (EAS), no matter what the circumstances may be P < 0.001. Both opposed to its legalization P < 0.001. Just 15% of physicians reported that they were asked by patients for assistance in dying. Both physicians 29.2% and patients 61.5% were in favor of withdrawing or withholding life-sustaining treatment to a patient with no chances of survival. Among patients no significant differences were observed for age, marital status, or underlying health status. Conclusions: A significant percentage of surveyed respondents were against EAS or its legalization. Patient views were primarily determined by religious beliefs rather than the disease severity. More debates on the matter are crucial in the ever-evolving world of clinical medicine. PMID:25374860

  19. Analysis on Soil Seed Bank Diversity Characteristics and Its Relation with Soil Physical and Chemical Properties after Substrate Addition

    PubMed Central

    He, Mengxuan; Lv, Lingyue; Li, Hongyuan; Meng, Weiqing; Zhao, Na

    2016-01-01

    Aims Considered as an essential measure in the application of soil seed bank (SSB) projects, the mixing of substrate and surface soil can effectively improve soil condition. This research is aimed at exploring the diversity characteristics of SSBs and the relationships between SSBs and soil properties. Methods Canonical correspondence analysis (CCA) was adopted to describe the ordination of SSBs on soil properties’ gradients; multiple linear regressions were adopted to analyze the relationship between average growth height and soil properties, density and soil properties. Results Experimental groups of mixed substrate (the mixture of organic and inorganic substrates) had high diversity indexes, especially the Shannon-Wiener Index compared with those of single substrate. Meanwhile, a higher number of species and increased density were also noted in those of mixed substrate. The best test group, No.16, had the highest diversity indexes with a Shannon-Wiener of 1.898, Simpson of 0.633 and Pielou of 0.717, and also showed the highest density of 14000 germinants /m2 and 21 species. In addition, an improvement of the soil’s chemical and physical properties was noted when the substrates were mixed. The mixed substrate of turfy soil and perlite could effectively enhance the soil moisture content, whilst a mixed substrate of rice husk carbon and vermiculite could improve the content of available potassium (AK) and phosphorus (AP) and strengthen soil fertility. The germinated plants also reflected obvious regularities of ordination on soil factor gradients. Three distinct cluster groups were presented, of which the first cluster was distributed in an area with a relatively higher content of AK and AP; the second cluster was distributed at places with relatively higher soil moisture content; and the third cluster of plants didn’t show any obvious relationship with soil physical and chemical properties. Through CCA analysis, AK and AP were considered the most important

  20. 17 CFR 230.432 - Additional information required to be included in prospectuses relating to tender offers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... required to be included in prospectuses relating to tender offers. 230.432 Section 230.432 Commodity and... prospectuses relating to tender offers. Notwithstanding the provisions of any form for the registration of securities under the Act, any prospectus relating to securities to be offered in connection with a...

  1. Present knowledge and perspectives on the role of copper in brake materials and related environmental issues: A critical assessment.

    PubMed

    Straffelini, Giovanni; Ciudin, Rodica; Ciotti, Alessandro; Gialanella, Stefano

    2015-12-01

    This critical review presents several aspects related to the use of copper as a main component in brake pads in road vehicles. The compositions of these materials are attracting increasing interest and concern due to the relative contribution of wear products to particulate matter emissions in the environment as a result of braking action even though there has been a reduction in exhaust products from internal combustion engines. We review the data on the main wear mechanisms in brake systems and highlight the positive role of copper. However, similar to other heavy metal emissions, even the release of copper into the atmosphere may have important environmental and health effects. Thus, several replacement strategies are being pursued, and the positive and negative features will be critically reviewed. Additionally, the future perspectives in materials development will be discussed. PMID:26408966

  2. Rheological and sensory behaviour of rice flour dough: effect of selected additives in relation to dough flattening.

    PubMed

    Dixit, Yash; Bhattacharya, Suvendu

    2015-08-01

    The handling of rice flour doughs in terms of sheeting, flattening and rolling is difficult due to the absence of gluten forming proteins; scope exists to improve these characteristics by incorporating appropriate additives during the preparation of rice doughs. Different levels of additives such as whey protein concentrate (WPC) (0-10 %), xanthan gum (0-5 %), sucrose (0-20 %) and salt (0-2 %) have been incorporated, and the rheological (small-deformation oscillation) as well as sensory characteristics have been determined, in addition to microstructural observations and finding inter-relationships. The second order polynomial can adequately explain the rheological parameters like storage modulus, loss modulus and complex viscosity (R = 0.863-0.889, p ≤ 0.01) while it is poor for phase angle (R = 0.659, p ≤ 0.01). Among these additives, xanthan gum imparts the strongest effect (significant at p ≤ 0.01) followed by whey protein concentrate. The effects of these additives are predominantly linear though quadratic effects are also significant in several cases. A cohesive microstructure with improved binding occurs with a high level (7.5 %) of WPC. It is concluded that a judicious selection of additives in appropriate levels can develop rice doughs that possess the desirable handling properties leading to preparation of products. PMID:26243905

  3. Regulatory issues related to functional foods and natural health products in Canada: possible implications for manufacturers of conjugated linoleic acid.

    PubMed

    Fitzpatrick, Kelley C

    2004-06-01

    The Canadian Food and Drugs Act and Regulations, through its definitions of food and drug, currently restricts health-related claims for foods, food ingredients, and natural health products (NHPs). Over the past few decades, scientific research has led to a large body of information that demonstrates the benefits for health of many food and NHP ingredients. Health Canada recognized the constraints of the current regulatory environment and started to develop regulations related to the allowance of health claims for functional foods and NHPs, including those foods and NHPs that would contain conjugated linoleic acid isomers. Health Canada has 3 initiatives under way in the area of health claims for foods: 1) to adopt the generic health claims of the United States within a Canadian context, 2) to develop scientific standards of evidence and a guidance document for supporting the validity of product-specific claims, and 3) to develop an overall regulatory framework for functional foods. In 2000, Health Canada announced approval for the use of 5 generic diet-related health claims: sodium and hypertension, calcium and osteoporosis, saturated and trans fat and cholesterol and coronary artery disease, fruits and vegetables and cancer, and sugar alcohols and dental caries. Under a separate initiative, Natural Health Products Regulations were published in the Canada Gazette Part II on June 18, 2003. The NHP Regulations came into force on January 1, 2004, with a transition period ranging from 2 y (for site licensing) to 6 y (for product licensing, for products already issued a drug identification number). PMID:15159260

  4. 30 CFR 250.807 - Additional requirements for subsurface safety valves and related equipment installed in high...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... valves and related equipment installed in high pressure high temperature (HPHT) environments. 250.807... pressure high temperature (HPHT) environments. (a) If you plan to install SSSVs and related equipment in an... greater than 15,000 psig or a temperature rating greater than 350 degrees Fahrenheit; (2) The...

  5. 30 CFR 250.807 - Additional requirements for subsurface safety valves and related equipment installed in high...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... valves and related equipment installed in high pressure high temperature (HPHT) environments. 250.807... related equipment installed in high pressure high temperature (HPHT) environments. (a) If you plan to... or well control equipment assigned a pressure rating greater than 15,000 psig or a temperature...

  6. Work-related reproductive, musculoskeletal and mental disorders among working women--history, current issues and future research directions.

    PubMed

    Kishi, Reiko; Kitahara, Teruyo; Masuchi, Ayumi; Kasai, Setsuko

    2002-04-01

    According to the recent changes of working environments and socio-economical conditions, the proportion of working women are increasing in Japan. Characteristics of occupational workload and stress of Japanese working women are consistent with those in many industrialized countries except man-dominant culture. In this review we describe the history, current issues, and future research directions on occupational health of working women, especially focused on reproductive health, work-related musculo-skeletal disorders (WMSDs), and mental disorders. In the reproductive health survey, traditionally main concern was about pregnancy outcomes, then fecundity studies, such as time to pregnancy, became topics recently. Future research will be shifted to outcomes not only during pregnancy but also disorders of hormonal balance and climacterium or health conditions after menopause. WMSDs are reviewed on mainly gender difference and its causative factors. Historically, mental health of working women in Japan has focused on the job stress of nurses. We compare results with a lot of recent researches in Europe and U.S.A., where interaction between occupational stress and family roles were studied. It is not easy to predict the prospective status of female workers in Japan, but social, workplace and familial supports will enhance their health promotion. PMID:12064551

  7. Living independently as an ethnic minority elder: a relational perspective on the issues of aging and ethnic minorities.

    PubMed

    Shin, Jung-Hye

    2014-06-01

    This study examines the residential experiences of Korean ethnic elders in affordable housing in the greater Chicago area, focusing on how patterns of social relationships that evolved around a geographical location and its urban infrastructure enabled the elders to achieve their desire for residential independence. Based on the theoretical concept of activity settings and social capital, the study suggests an integrated theoretical model where social capital is understood as an embedded asset of an activity setting. Methodologically, this study uses a combined method of qualitative interviews with 138 Korean elders in affordable housing in the greater Chicago area and a geographic analysis of their social relationships in order to present associations among social relationships, urban infrastructures, and the shared value of independence within their residential communities. The study findings indicate that the elders mobilized ethnic businesses, urban infrastructures, and the collective efficacy of groups to achieve the shared goal of maintaining residential independence. In each community, a cultural broker acted as an important bridge between the community of ethnic minorities and the larger social networks coexisting within the community boundary. The relational perspective as a potent ground for understanding and further solving the issues of aging and ethnicity is highlighted. PMID:24722777

  8. Special Issues Related to Hematopoietic Stem Cell Transplantation in the Eastern Mediterranean Region and the First Regional Activity Report

    PubMed Central

    Aljurf, Mahmoud; Zaidi, Syed Z; El Solh, Hassan; Hussain, Fazal; Ghavamzadeh, Ardeshir; Mahmoud, Hossam Kamel; Shamsi, Tahir; Othman, Tarek Ben; Sarhan, Mahmoud M.; Dennison, David; Ibrahim, Ahmad; Benchekroun, Said; Chaudhri, Naeem; Labar, Boris; Horowitz, Mary; Niederwieser, Dietger; Gratwohl, Alois

    2012-01-01

    Although several centers are now performing allogeneic HSCT in the Eastern Mediterranean (EM) region, the availability is still limited. Special issues including compatible donor availability and potential for alternate donor programs are discussed. In comparison to Europe & North America, differences in pattern of diseases and pre-HSCT general status particularly for patients with BM failure are described. Other differences including high seropositivity for CMV, Hepatitis B and C infection and specific observations about GVHD with its relation to genetically homogeneous community are also discussed. We report that a total of 17 HSCT programs (performing 5 or more HSCTs annually) exist in 9 countries of the EM region. Only 6 programs are currently reporting to EBMT or IBMTR. A total of 7617 HSCTs have been performed by these programs including 5701 allogeneic HSCTs. Due to low HSCT team density (1.5583 teams/10 million inhabitants vs. 14.4333 in Europe) and very low HSCT team distribution (0.2729 teams/10,000 sq km area vs. <1 to 6 teams in Europe). GNI/capita had no clear association with low HSCT activity; however improvement in infrastructure & formation of EM regional HSCT registry are needed. PMID:19043456

  9. Anaerobic digestion of swine manure under natural zeolite addition: VFA evolution, cation variation, and related microbial diversity.

    PubMed

    Lin, Lin; Wan, Chunli; Liu, Xiang; Lei, Zhongfang; Lee, Duu-Jong; Zhang, Yi; Tay, Joo Hwa; Zhang, Zhenya

    2013-12-01

    Batch experiments were carried out on anaerobic digestion of swine manure under 10 % of total solids and 60 g/L of zeolite addition at 35 °C. Four distinctive volatile fatty acid (VFAs) evolution stages were observed during the anaerobic process, i.e., VFA accumulation, acetic acid (HAc) and butyric acid (HBu) utilization, propionic acid (HPr) and valeric acid (HVa) degradation, and VFA depletion. Large decreases in HAc/HBu and HPr/HVa occurred respectively at the first and second biogas peaks. Biogas yield increased by 20 % after zeolite addition, about 356 mL/g VSadded with accelerated soluble chemical oxygen demand degradation and VFA (especially HPr and HBu) consumption in addition to a shortened lag phase between the two biogas peaks. Compared with Ca(2+) and Mg(2+) (100-300 mg/L) released from zeolite, simultaneous K(+) and NH4 (+) (580-600 mg/L) adsorptions onto zeolite particles contributed more to the enhanced biogasification, resulting in alleviated inhibition effects of ammonium on acidogenesis and methanogenesis, respectively. All the identified anaerobes could be grouped into Bacteroidetes and Firmicutes, and zeolite addition had no significant influence on the microbial biodiversity in this study. PMID:24270923

  10. 76 FR 38937 - World Trade Center Health Program Requirements for the Addition of New WTC-Related Health Conditions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ... (see Delegation of Authority, 76 FR 31337, May 31, 2011). All references to the WTC Program... July 1, 2011 Part VII Department of Health and Human Services 42 CFR Part 88 World Trade Center Health... SERVICES 42 CFR Part 88 RIN 0920-AA45 World Trade Center Health Program Requirements for the Addition...

  11. Lessons from the past: materials-related issues in an ultra-supercritical boiler at Eddystone plant

    SciTech Connect

    Henry, J.; Zhou, G.; Ward, T.

    2007-07-01

    Major research efforts have made progress toward the development of coal-fired ultra-supercritical steam generators that will operate at efficiencies approaching 50% based on HHV. A component test facility designed to evaluate operation of major steam generator components at 700{degree}C (1292{degree}F) will soon be operational in Germany, and the first demonstration plant incorporating advanced ultra-supercritical technology could be constructed as soon as the year 2010. The question posed by those who will be responsible for the operation of these new ultra-supercritical power plants is obvious: will they perform reliably under the conditions of flexible operation that are likely to be imposed by modern de-regulated markets? The real intent of this question is more subtle: do the materials and methods of construction exist to build these advanced coal-fired boilers. In large part, the answer to that question lies in a US power plant located not far from the Philadelphia airport. The plant is Exelon's Eddystone plant. The steam generator for Unit I at that plant has operated successfully for over 44 years at steam conditions more advanced than any other coal-fired unit in operation today. This paper reviews salient features of the operating history of Eddystone 1, focussing on the materials-related problems that forced a modest retreat from the original and unprecedented design conditions, emphasizing the record of many years of reliable operation at aggressive steam conditions. It then discusses a few of the more significant materials-related issues involved in operating a steam generator at Eddystone-like conditions as a basis for arguing that there exists today the materials and manufacturing understanding necessary to construct an advanced ultra-supercritical unit that will operate efficiently and reliably.

  12. Developmental and ethnic issues experienced by emerging adult African American women related to developing a mature love relationship.

    PubMed

    Tyson, Sheryl Y

    2012-01-01

    This qualitative study explored perspectives of emerging adult African American women on the development of mature love relationships. Inductive analysis of focus group interviews, conducted with a purposive sample of 31 African American women, yielded themes related to relationship goals and characteristics, and interpersonal and societal challenges to finding the right partner and developing a mature love relationship. Core categories that emerged from analysis of the discussions were (1) age and relationship goal differences within the emerging adult group, (2) mature love relationship goals and characteristics, (3) interpersonal obstacles to finding the right partner, and (4) societal obstacles to finding the right partner. Two approaches-black womanist/feminist thought (Collins, 2000 ; Walker, 1983 ) and relationship maturity theory (Paul & White, 1990 )-were then combined to explain the influence of historic and contemporary interpersonal and societal factors on developmental and ethnic issues that challenge positive gender identity formation, hasten intimacy maturity, and hinder the development of mature love relationships among emerging adult African American women. For these women, premature responsibility, especially early caregiver burden, was related to the early development of intimacy capacity and the desire for a mature love relationship, to be protected, and to have someone to help carry the load. Interracial dating, negative stereotypic images of African American women, and even positive images of enduring black love relationships posed difficult challenges to positive identity formation and intimacy maturity. A primary challenge was to counteract negative stereotypic images, so that they could develop their own self-identities as women and as relationship partners. PMID:22224965

  13. Prevalence of Feeding Related Issues/Difficulties in Taiwanese Children with History of Prematurity, 2003-2006

    ERIC Educational Resources Information Center

    Howe, Tsu-Hsin; Hsu, Chyong-Hsin; Tsai, Mei-Wun

    2010-01-01

    Feeding problems are common problems seen in premature infants following their discharge from the NICU. However, the prevalence of feeding issues and failure to thrive among preterm infants in Taiwan is uncertain. All former studies of prevalence and identifications of feeding issues were from western countries. Those findings are therefore not…

  14. The Need for an Enlarged Vision and Additional Perspectives of Public Relations in the 21st Century: A Challenge to Existing Paradigms.

    ERIC Educational Resources Information Center

    Kruckeberg, Dean

    This paper asserts that an enlarged vision and additional perspectives of public relations will be needed in the 21st century: vision and perspectives that will not only complement but challenge existing paradigms. Future communication technological phenomena will require dramatic changes in public relations practitioners' efforts in relationship-…

  15. 30 CFR 250.807 - Additional requirements for subsurface safety valves and related equipment installed in high...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... valves and related equipment installed in high pressure high temperature (HPHT) environments. 250.807... installed in high pressure high temperature (HPHT) environments. (a) If you plan to install SSSVs and... assigned a pressure rating greater than 15,000 psig or a temperature rating greater than 350...

  16. 30 CFR 250.807 - Additional requirements for subsurface safety valves and related equipment installed in high...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... valves and related equipment installed in high pressure high temperature (HPHT) environments. 250.807... installed in high pressure high temperature (HPHT) environments. (a) If you plan to install SSSVs and... assigned a pressure rating greater than 15,000 psig or a temperature rating greater than 350...

  17. 30 CFR 250.807 - Additional requirements for subsurface safety valves and related equipment installed in high...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... valves and related equipment installed in high pressure high temperature (HPHT) environments. 250.807... installed in high pressure high temperature (HPHT) environments. (a) If you plan to install SSSVs and... assigned a pressure rating greater than 15,000 psig or a temperature rating greater than 350...

  18. Inhaled pulmonary vasodilators for persistent pulmonary hypertension of the newborn: safety issues relating to drug administration and delivery devices

    PubMed Central

    Cosa, Nathan; Costa, Edward

    2016-01-01

    Treatment for persistent pulmonary hypertension of the newborn (PPHN) aims to reduce pulmonary vascular resistance while maintaining systemic vascular resistance. Selective pulmonary vasodilation may be achieved by targeting pulmonary-specific pathways or by delivering vasodilators directly to the lungs. Abrupt withdrawal of a pulmonary vasodilator can cause rebound pulmonary hypertension. Therefore, use of consistent delivery systems that allow for careful monitoring of drug delivery is important. This manuscript reviews published studies of inhaled vasodilators used for treatment of PPHN and provides an overview of safety issues associated with drug delivery and delivery devices as they relate to the risk of rebound pulmonary hypertension. Off-label use of aerosolized prostacyclins and an aerosolized prostaglandin in neonates with PPHN has been reported; however, evidence from large randomized clinical trials is lacking. The amount of a given dose of aerosolized drug that is actually delivered to the lungs is often unknown, and the actual amount of drug deposited in the lungs can be affected by several factors, including patient size, nebulizer used, and placement of the nebulizer within the breathing circuit. Inhaled nitric oxide (iNO) is the only pulmonary vasodilator approved by the US Food and Drug Administration for the treatment of PPHN. The iNO delivery device, INOmax DSIR®IR, is designed to constantly monitor NO, NO2, and O2 deliveries and is equipped with audible and visual alarms to alert providers of abrupt discontinuation and incorrect drug concentration. Other safety features of this device include two independent backup delivery systems, a backup drug cylinder, a battery that provides up to 6 hours of uninterrupted medication delivery, and 27 alarms that monitor delivery, dosage, and system functions. The ability of the drug delivery device to provide safe, consistent dosing is important to consider when selecting a pulmonary vasodilator. PMID

  19. Inhaled pulmonary vasodilators for persistent pulmonary hypertension of the newborn: safety issues relating to drug administration and delivery devices.

    PubMed

    Cosa, Nathan; Costa, Edward

    2016-01-01

    Treatment for persistent pulmonary hypertension of the newborn (PPHN) aims to reduce pulmonary vascular resistance while maintaining systemic vascular resistance. Selective pulmonary vasodilation may be achieved by targeting pulmonary-specific pathways or by delivering vasodilators directly to the lungs. Abrupt withdrawal of a pulmonary vasodilator can cause rebound pulmonary hypertension. Therefore, use of consistent delivery systems that allow for careful monitoring of drug delivery is important. This manuscript reviews published studies of inhaled vasodilators used for treatment of PPHN and provides an overview of safety issues associated with drug delivery and delivery devices as they relate to the risk of rebound pulmonary hypertension. Off-label use of aerosolized prostacyclins and an aerosolized prostaglandin in neonates with PPHN has been reported; however, evidence from large randomized clinical trials is lacking. The amount of a given dose of aerosolized drug that is actually delivered to the lungs is often unknown, and the actual amount of drug deposited in the lungs can be affected by several factors, including patient size, nebulizer used, and placement of the nebulizer within the breathing circuit. Inhaled nitric oxide (iNO) is the only pulmonary vasodilator approved by the US Food and Drug Administration for the treatment of PPHN. The iNO delivery device, INOmax DSIR®IR, is designed to constantly monitor NO, NO2, and O2 deliveries and is equipped with audible and visual alarms to alert providers of abrupt discontinuation and incorrect drug concentration. Other safety features of this device include two independent backup delivery systems, a backup drug cylinder, a battery that provides up to 6 hours of uninterrupted medication delivery, and 27 alarms that monitor delivery, dosage, and system functions. The ability of the drug delivery device to provide safe, consistent dosing is important to consider when selecting a pulmonary vasodilator. PMID

  20. Change in fatigue property and its relation to critical current for YBCO coated conductor with additional Cu layer

    NASA Astrophysics Data System (ADS)

    Yoshida, Y.; Hojo, M.; Sugano, M.; Adachi, T.; Inoue, Y.; Shikimachi, K.; Hirano, N.; Nagaya, S.

    2009-10-01

    YBa 2Cu 3O 7-δ, (YBCO) coated conductors with an additional Cu layer are expected to be applied as coils used in superconducting magnetic energy storage, SMES. In the operation of SMES, large cyclic hoop stress is applied to the coated conductor in the longitudinal direction. In the present study, we carried out fatigue tests in liquid nitrogen, LN 2, and measured the critical current, I c, after a specific number of fatigue cycles to clarify its fatigue fracture mechanism. All fatigue tests were carried out under a stress ratio (the ratio of the minimum to maximum load) of 0.5. The frequency of stress cycling was 30 Hz. Our results showed that the addition of a Cu layer increased the fatigue strength after 10 6 cycles, F, by about 19%. Decrease of I c was more than 30% of the initial critical current, I c0, without loading at the point of final overall fracture when the maximum load in the stress cycles was close to that corresponding to irreversible strain. Furthermore, microscopic observation and the change in I c showed that fatigue fracture mainly initiated from the Hastelloy C-276 substrate. Fatigue fracture also initiated from the Cu layer, but only when the maximum load was approximately F.

  1. Polymelous layer chick displaying additional malformations of the hind gut: case report and in-depth review of related literature.

    PubMed

    Hirschberg, R M; Saleh, M; Kaiser, S; Lierz, M; Hafez, H M; Bragulla, H H

    2012-08-01

    A case report of a male 6-day-old male layer chick featuring incomplete polymelia of the hind limbs and hindgut malformations is presented. The chick was submitted to computed tomography (CT) examination and subsequent anatomical dissection. Apart from the two supernumerary hind limbs, the anatomical dissection revealed additional hindgut alterations: three uniform-sized caeca flanked the ileum, and the rectum branched into paired cloacae. The supernumerary hind limbs were localized caudal to the normal hind limbs in an inverted position and were attached to pelvic girdle elements and to a curtate pygostyle. They featured a prominent unpaired femur besides paired tibiotarsi, tarsometatarsi and species-specific phalanges of the toes. Additionally, two separate bones attached to the caudoventral aspect of the regular hip bones were developed. The supernumerary limbs were in part mobile and received nerve and vascular supply. Digital 3D-reconstruction based on the CT datasets revealed the osseous components of the malformed body parts. The possible morphogenesis including an in-depth literature review and the clinical implications of the reported malformations are discussed. PMID:22250842

  2. PREFACE OF SPECIAL ISSUE OF AEROSOL SCIENCE AND TECHNOLOGY FOR PARTICULATE MATTER SUPERSITES PROGRAM AND RELATED STUDIES

    EPA Science Inventory

    This article is the preface or editors note to a dedicated issue of Aerosol Science and Technology, journal of the American Association for Aerosol Research. It includes a selection of scientific papers from the specialty conference entitled, "Particulate Matter Supersites ...

  3. Medicolegal issues.

    PubMed

    Torres, Abel; Konda, Sailesh; Nino, Tanya; de Golian, Emily

    2016-01-01

    The legal landscape in dermatology is constantly evolving. Dermatologists should nurture strong physician-patient relationships with proper informed consent and stay abreast of legal issues as they pertain to today's practice of medicine. Medicolegal issues that have risen to the forefront include wrong-site surgery, delegation of procedures to nonphysician operators, and compounding of medications. Additionally, although the marriage of health care and technology has facilitated our practice of medicine, it has opened doors to new medicolegal pitfalls associated with the use of electronic medical records, teledermatology, and even social media. This contribution will highlight some of the common medicolegal issues in dermatology along with recommendations to minimize exposure to litigation. PMID:26773630

  4. Unaddressed Issues

    ERIC Educational Resources Information Center

    Rochester, J. Martin

    2005-01-01

    Walter Parker's January article, "Teaching Against Idiocy," raises important and fascinating issues relating to the proper role and function of the K-12 social studies classroom. Although J. Martin Rochester, the author of this article, agrees with his basic premise that schools obviously have an obligation to help promote citizenship education,…

  5. TerraFirma and SubCoast: using satellite data for flood related issues and ground subsidence

    NASA Astrophysics Data System (ADS)

    Gruijters, Stephan; van der Korgt, Rob

    2013-04-01

    Subsidence is a typical geohazard for coastal lowland areas and river basins. Subsidence, when combined with sea level rise and extreme weather events (windstorms, heavy rainfall and related river discharges) aggravates flood risk, increasing the hazard by deteriorating the flood defence and increasing the exposure as a result of the subsiding terrain. Therefore, subsidence and flood risk are closely related. Coastal lowland areas are often densely populated with varied land use including industry, agriculture and infrastructure. If flood defence systems are not in place or fail to function, a flooding event will result in substantial economic damage and possible loss of life. The probability of a flood event increases for a subsiding flood defence structure, by an increase in the probability of overtopping. Additionally, with a subsiding hinterland the difference in height between the extreme water level and the exposed terrain increases, destabilising the flood defence structures. Secondly, the impact of a flood will be larger for subsided terrain by an increase in inundated area both in depth and in extent. This means that terrain movement is a relevant parameter for all flood prone areas, whether protected by flood defence structures or not. The shallow subsurface in lowland areas frequently contains compressible soils which are vulnerable to subsidence. Furthermore, these deposits have a substantial spatial variability due to sedimentation and erosion processes, introducing a spatial component in the vulnerability to subsidence. In addition to natural processes of ripening, compaction and peat oxidation, human factors also influence the terrain level: The extraction of natural resources like groundwater, salt, oil or gas in deeper layers (ranging from tens of metres up to thousands of metres) may cause subsidence at the surface. Knowing the magnitude of changes in terrain level over the past decades and understanding the processes behind it is key for

  6. Supplementing High-Density SNP Microarrays for Additional Coverage of Disease-Related Genes: Addiction as a Paradigm

    SciTech Connect

    SacconePhD, Scott F; Chesler, Elissa J; Bierut, Laura J; Kalivas, Peter J; Lerman, Caryn; Saccone, Nancy L; Uhl, George R; Li, Chuan-Yun; Philip, Vivek M; Edenberg, Howard; Sherry, Steven; Feolo, Michael; Moyzis, Robert K; Rutter, Joni L

    2009-01-01

    Commercial SNP microarrays now provide comprehensive and affordable coverage of the human genome. However, some diseases have biologically relevant genomic regions that may require additional coverage. Addiction, for example, is thought to be influenced by complex interactions among many relevant genes and pathways. We have assembled a list of 486 biologically relevant genes nominated by a panel of experts on addiction. We then added 424 genes that showed evidence of association with addiction phenotypes through mouse QTL mappings and gene co-expression analysis. We demonstrate that there are a substantial number of SNPs in these genes that are not well represented by commercial SNP platforms. We address this problem by introducing a publicly available SNP database for addiction. The database is annotated using numeric prioritization scores indicating the extent of biological relevance. The scores incorporate a number of factors such as SNP/gene functional properties (including synonymy and promoter regions), data from mouse systems genetics and measures of human/mouse evolutionary conservation. We then used HapMap genotyping data to determine if a SNP is tagged by a commercial microarray through linkage disequilibrium. This combination of biological prioritization scores and LD tagging annotation will enable addiction researchers to supplement commercial SNP microarrays to ensure comprehensive coverage of biologically relevant regions.

  7. Stiff-person syndrome (SPS) and anti-GAD-related CNS degenerations: protean additions to the autoimmune central neuropathies.

    PubMed

    Ali, Fatima; Rowley, Merrill; Jayakrishnan, Bindu; Teuber, Suzanne; Gershwin, M Eric; Mackay, Ian R

    2011-09-01

    Stiff Person Syndrome (SPS) is a rare autoimmune neurological disease attributable to autoantibodies to glutamic acid decarboxylase (anti-GAD) more usually associated with the islet beta cell destruction of autoimmune type 1 diabetes (T1D). SPS is characterized by interference in neurons with the synthesis/activity of the inhibitory neurotransmitter gamma amino butyric acid (GABA) resulting in the prototypic progressive spasmodic muscular rigidity of SPS, or diverse neurological syndromes, cerebellar ataxia, intractable epilepsy, myoclonus and several others. Remarkably, a single autoantibody, anti-GAD, can be common to widely different disease expressions, i.e. T1D and SPS. One explanation for these data is the differences in epitope engagement between the anti-GAD reactivity in SPS and T1D: in both diseases, anti-GAD antibody reactivity is predominantly to a conformational epitope region in the PLP- and C-terminal domains of the 65 kDa isoform but, additionally in SPS, there is reactivity to conformational epitope(s) on GAD67, and short linear epitopes in the C-terminal region and at the N-terminus of GAD65. Another explanation for disease expressions in SPS includes ready access of anti-GAD to antigen sites due to immune responsiveness within the CNS itself according to intrathecal anti-GAD-specific B cells and autoantibody. Closer study of the mysterious stiff-person syndrome should enhance the understanding of this disease itself, and autoimmunity in general. PMID:21680149

  8. Supplementing High-Density SNP Microarrays for Additional Coverage of Disease-Related Genes: Addiction as a Paradigm

    PubMed Central

    Saccone, Scott F.; Bierut, Laura J.; Chesler, Elissa J.; Kalivas, Peter W.; Lerman, Caryn; Saccone, Nancy L.; Uhl, George R.; Li, Chuan-Yun; Philip, Vivek M.; Edenberg, Howard J.; Sherry, Stephen T.; Feolo, Michael; Moyzis, Robert K.; Rutter, Joni L.

    2009-01-01

    Commercial SNP microarrays now provide comprehensive and affordable coverage of the human genome. However, some diseases have biologically relevant genomic regions that may require additional coverage. Addiction, for example, is thought to be influenced by complex interactions among many relevant genes and pathways. We have assembled a list of 486 biologically relevant genes nominated by a panel of experts on addiction. We then added 424 genes that showed evidence of association with addiction phenotypes through mouse QTL mappings and gene co-expression analysis. We demonstrate that there are a substantial number of SNPs in these genes that are not well represented by commercial SNP platforms. We address this problem by introducing a publicly available SNP database for addiction. The database is annotated using numeric prioritization scores indicating the extent of biological relevance. The scores incorporate a number of factors such as SNP/gene functional properties (including synonymy and promoter regions), data from mouse systems genetics and measures of human/mouse evolutionary conservation. We then used HapMap genotyping data to determine if a SNP is tagged by a commercial microarray through linkage disequilibrium. This combination of biological prioritization scores and LD tagging annotation will enable addiction researchers to supplement commercial SNP microarrays to ensure comprehensive coverage of biologically relevant regions. PMID:19381300

  9. Test-retest reproducibility of the relative dose response for vitamin A status in Guatemalan adults: issues of diagnostic specificity.

    PubMed

    Morrow, F D; Guerrero, A M; Russell, R M; Dallal, G; Solomons, N W

    1990-07-01

    The relative dose response (RDR) test was examined with regard to specificity and reproducibility in subjects with adequate dietary intake and normal liver reserves of vitamin A. Twelve subjects were administered an RDR test four times over 22 d, including one placebo test in which the oral dose of vitamin A was omitted. Additionally, static measures of retinol, tocopherol, retinol binding protein (RBP) and prealbumin (PAL) were taken to determine the intra- and inter-individual coefficient of variation for these blood constituents. Intra-individual coefficients of variation were as follows: retinol, 8.8%; RBP, 11.5%; PAL, 7.6%; and alpha-tocopherol, 8.8%. The mean RDR in vitamin A-replete subjects was 1.2% and ranged from approximately -25% to 11%. No differences were observed between placebo and true RDR (i.e., with vitamin A) test responses, and there was no difference among the three true RDRs over a period of 22 d. Consistent with the hypothesis upon which the RDR test is based, nascently absorbed vitamin A evidently entered a storage pool in the liver of vitamin A-replete subjects without immediate release to peripheral sites of utilization. Because the RDR test results were normal in all subjects, the procedure appears to offer high test specificity and does not falsely diagnose hypovitaminosis A. Nevertheless, the magnitude and direction of the RDR within an individual over 22 d were highly variable, and this variability may preclude the use of a single measure of the RDR to grade the relative vitamin A nutriture of an individual subject. PMID:2366108

  10. Mor-Dalphos-Pd (II) oxidative addition complexes and related NH3 adducts: Insights into bonding and nonbonding interactions

    NASA Astrophysics Data System (ADS)

    de Lima Batista, Ana P.; Braga, Ataualpa A. C.

    2016-09-01

    The stabilizing effects and bonding properties of the Pd metallic center in [(κ2 -P,N-Mor-Dalphos)Pd(Ar)Cl] complexes and related NH3 adducts were investigated by density functional theory (DFT), the intrinsic bond orbital (IBO) approach and the Su-Li energy decomposition method (Su-Li EDA). The IBO analysis showed that the P atom from the P,N-Mor-Dalphos structure has stabilizing contributions in all Pd-Cl and Pd-NH3 bonds in the complexes. According to the Su-Li energy decomposition analysis, the main energy that drives the interaction between the [Mor-Dalphos-Pd(Ar)] moiety and Cl- is the electrostatic term, therefore, the electrostatic energy interaction between them might be an important factor for taking into account when designing other [Mor-Dalphos-Pd(Ar)]-Cl precatalysts.

  11. Quantitative Method To Determine Sporicidal Decontamination of Building Surfaces by Gaseous Fumigants, and Issues Related to Laboratory-Scale Studies▿

    PubMed Central

    Rastogi, Vipin K.; Wallace, Lalena; Smith, Lisa S.; Ryan, Shawn P.; Martin, Blair

    2009-01-01

    Chlorine dioxide gas and vaporous hydrogen peroxide sterilant have been used in the cleanup of building interiors contaminated with spores of Bacillus anthracis. A systematic study, in collaboration with the U.S. Environmental Protection Agency, was jointly undertaken by the U.S. Army-Edgewood Chemical Biological Center to determine the sporicidal efficacies of these two fumigants on six building structural materials: carpet, ceiling tile, unpainted cinder block, painted I-beam steel, painted wallboard, and unpainted pinewood. Critical issues related to high-throughput sample processing and spore recovery from porous and nonporous surfaces included (i) the extraction of spores from complex building materials, (ii) the effects of titer challenge levels on fumigant efficacy, and (iii) the impact of bioburden inclusion on spore recovery from surfaces and spore inactivation. Small pieces (1.3 by 1.3 cm of carpet, ceiling tile, wallboard, I-beam steel, and pinewood and 2.5 by 1.3 cm for cinder block) of the materials were inoculated with an aliquot of 50 μl containing the target number (1 × 106, 1 × 107, or 1 × 108) of avirulent spores of B. anthracis NNR1Δ1. The aliquot was dried overnight in a biosafety cabinet, and the spores were extracted by a combination of a 10-min sonication and a 2-min vortexing using 0.5% buffered peptone water as the recovery medium. No statistically significant drop in the kill efficacies of the fumigants was observed when the spore challenge level was increased from 6 log units to 8 log units, even though a general trend toward inhibition of fumigant efficacy was evident. The organic burden (0 to 5%) in the spore inoculum resulted in a statistically significant drop in spore recovery (at the 2 or 5% level). The effect on spore killing was a function of the organic bioburden amount and the material type. In summary, a high-throughput quantitative method was developed for determining the efficacies of fumigants, and the spore recoveries

  12. Method for Derivatization and Detection of Chemical Weapons Convention Related Sulfur Chlorides via Electrophilic Addition with 3-Hexyne.

    PubMed

    Goud, D Raghavender; Pardasani, Deepak; Purohit, Ajay Kumar; Tak, Vijay; Dubey, Devendra Kumar

    2015-07-01

    Sulfur monochloride (S2Cl2) and sulfur dichloride (SCl2) are important precursors of the extremely toxic chemical warfare agent sulfur mustard and classified, respectively, into schedule 3.B.12 and 3.B.13 of the Chemical Weapons Convention (CWC). Hence, their detection and identification is of vital importance for verification of CWC. These chemicals are difficult to detect directly using chromatographic techniques as they decompose and do not elute. Until now, the use of gas chromatographic approaches to follow the derivatized sulfur chlorides is not reported in the literature. The electrophilic addition reaction of sulfur monochloride and sulfur dichloride toward 3-hexyne was explored for the development of a novel derivatization protocol, and the products were subjected to gas chromatography-mass spectrometric (GC-MS) analysis. Among various unsaturated reagents like alkenes and alkynes, symmetrical alkyne 3-hexyne was optimized to be the suitable derivatizing agent for these analytes. Acetonitrile was found to be the suitable solvent for the derivatization reaction. The sample preparation protocol for the identification of these analytes from hexane spiked with petrol matrix was also optimized. Liquid-liquid extraction followed by derivatization was employed for the identification of these analytes from petrol matrix. Under the established conditions, the detection and quantification limits are 2.6 μg/mL, 8.6 μg/mL for S2Cl2 and 2.3 μg/mL, 7.7 μg/mL for SCl2, respectively, in selected ion monitoring (SIM) mode. The calibration curve had a linear relationship with y = 0.022x - 0.331 and r(2) = 0.992 for the working range of 10 to 500 μg/mL for S2Cl2 and y = 0.007x - 0.064 and r(2) = 0.991 for the working range of 10 to 100 μg/mL for SCl2, respectively. The intraday RSDs were between 4.80 to 6.41%, 2.73 to 6.44% and interday RSDs were between 2.20 to 7.25% and 2.34 to 5.95% for S2Cl2 and SCl2, respectively. PMID:26054007

  13. Numerical Simulation of the Issues Related to Uranium Mining and Tailings Management in Continuous Permafrost Zones in Nunavut, Canada

    NASA Astrophysics Data System (ADS)

    Su, X.; Booshehrian, A.; Wan, R.

    2013-12-01

    In order to understand the potential environmental effects of a uranium mining and tailings management project in northern Canada, numerical simulations have been conducted on the Kiggavik project to investigate the issues of permafrost degradation, mine pit floor heave and slope deformation, and potential inflow into the mine pits during mining and tailings disposition. The project includes the development of three open pit mines, the Main Zone, the Centre Zone, and the East Zone at the Kiggavik site, and an open pit mine and an underground mine at the Sissons site. The mined ore will be milled at the Kiggavik site and the mill tailings will be disposed back into the three open pits at Kiggavik. The mining and milling operation of the project will last about 15 to 20 years. Permafrost at the Kiggavik site extends between 220 m to 240 m below ground surface, while permafrost at the Sissons site ranges from 260 m to 280 m below ground surface. The centre zone and the east zone will be excavated within permafrost, while the main zone and the open pit at Sissons will penetrate the permafrost layer. A high artesian pressure due to the permafrost constraint was measured at both Kiggavik and Sissons sites, and was found to be higher than the ground surface. The results of numerical simulations on the behavior of the continuous permafrost layer indicate that permafrost degradation around the pits or tailings management facilities is not significant during mine operation. No open talik would form below the excavated area as a result of depositing warm tailings in both East Zone and Centre Zone pits. A thin thawed zone of 3 to 5 m on the side of Centre Zone pit is developed, while the thawed area at the bottom of the pit extends to a depth of 10 to 15 m. For the Main Zone, where the excavation breaks through the permafrost, an open talik would remain following the operation period. The warm tailings would cause a 20 m thick thawed zone along the lower sides of the pit. With

  14. Development and Preliminary Psychometric Evaluation of the Domestic Violence-Related Financial Issues Scale (DV-FI)

    ERIC Educational Resources Information Center

    Weaver, Terri L.; Sanders, Cynthia K.; Campbell, Carole L.; Schnabel, Meg

    2009-01-01

    Intimate partner violence (IPV) occurs at disproportionate rates within impoverished groups of women and can include economic abuse as a form of psychological maltreatment. The current study developed a comprehensive assessment of the unique financial issues facing female victims of IPV using a sheltered sample (N = 113). An exploratory factor…

  15. Study of Issues Related to the Implementation of Computer Technology in Schools. Final Report, July, 1981. Technical Report No. 2.

    ERIC Educational Resources Information Center

    Sheingold, Karen; And Others

    This study examined ways in which microcomputers are used in schools and the complex issues that surround their implementation. Three fictional geographically distinct school districts with a diversity of microcomputer applications at both the elementary and secondary levels were studied: Salerno, a large southern city; Granite, a midwestern city;…

  16. Ethical Issues in Environmental Health Research Related to Public Health Emergencies: Reflections on the GuLF STUDY

    PubMed Central

    Miller, Aubrey K.; Kwok, Richard K.; Engel, Lawrence S.; Sandler, Dale P.

    2015-01-01

    Summary Health research in the context of an environmental disaster with implications for public health raises challenging ethical issues. This article explores ethical issues that arose in the Gulf Long-term Follow-up Study (GuLF STUDY) and provides guidance for future research. Ethical issues encountered by GuLF STUDY investigators included a) minimizing risks and promoting benefits to participants, b) obtaining valid informed consent, c) providing financial compensation to participants, d) working with vulnerable participants, e) protecting participant confidentiality, f) addressing conflicts of interest, g) dealing with legal implications of research, and h) obtaining expeditious review from the institutional review board (IRB), community groups, and other committees. To ensure that ethical issues are handled properly, it is important for investigators to work closely with IRBs during the development and implementation of research and to consult with groups representing the community. Researchers should consider developing protocols, consent forms, survey instruments, and other documents prior to the advent of a public health emergency to allow for adequate and timely review by constituents. When an emergency arises, these materials can be quickly modified to take into account unique circumstances and implementation details. PMID:26325057

  17. Did I Tell You That? Ethical Issues Related to Using Computational Methods to Discover Non-Disclosed Patient Characteristics.

    PubMed

    Cato, Kenrick D; Bockting, Walter; Larson, Elaine

    2016-07-01

    Widespread availability of electronic health records coupled with sophisticated statistical methods offer great potential for a variety of applications for health and disease surveillance, developing predictive models and advancing decision support for clinicians. However, use of "big data" mining and discovery techniques has also raised ethical issues such as how to balance privacy and autonomy with the wider public benefits of data sharing. Furthermore, electronic data are being increasingly used to identify individual characteristics, which can be useful for clinical prediction and management, but were not previously disclosed to a clinician. This process in computer parlance is called electronic phenotyping, and has a number of ethical implications. Using the Belmont Report's principles of respect for persons, beneficence, and justice as a framework, we examined the ethical issues posed by electronic phenotyping. Ethical issues identified include the ability of the patient to consent for the use of their information, the ability to suppress pediatric information, ensuring that the potential benefits justify the risks of harm to patients, and acknowledging that the clinician's biases or stereotypes, conscious or unintended, may become a factor in the therapeutic interaction. We illustrate these issues with two vignettes, using the person characteristic of gender minority status (i.e., transgender identity) and health history characteristic of substance abuse. Data mining has the potential to uncover patient characteristics previously obscured, which can provide clinicians with beneficial clinical information. Hence, ethical guidelines must be updated to ensure that electronic phenotyping supports the principles of respect for persons, beneficence, and justice. PMID:27534587

  18. Experiences and Issues Related to the Format of Bilingual Tests: Dual Language Test Booklets versus Two Different Test Booklets.

    ERIC Educational Resources Information Center

    Stansfield, Charles W.

    This report, requested by the Massachusetts Department of Education, addresses the issue of the format of native language assessments of students' educational achievement. There are two basic options when administering a translation or adaptation of a test in another language: one is to produce test booklets in both languages and then determine…

  19. Students' Socioscientific Reasoning and Decision-Making on Energy-Related Issues--Development of a Measurement Instrument

    ERIC Educational Resources Information Center

    Sakschewski, Mark; Eggert, Sabina; Schneider, Susanne; Bögeholz, Susanne

    2014-01-01

    The concept of energy is one key component of science education curricula worldwide. While it is still being taught in many science classrooms from a mainly conceptual knowledge perspective, the need to frame the concept of energy as a socioscientific issue and implement it in the context of citizenship education and education for sustainable…

  20. High School Students' Informal Reasoning Regarding a Socio-Scientific Issue, with Relation to Scientific Epistemological Beliefs and Cognitive Structures

    ERIC Educational Resources Information Center

    Wu, Ying-Tien; Tsai, Chin-Chung

    2011-01-01

    This study investigated the relationship among 68 high school students' scientific epistemological beliefs (SEBs), cognitive structures regarding nuclear power usage, and their informal reasoning regarding this issue. Moreover, the ability of students' SEBs as well as their cognitive structures for predicting their informal reasoning regarding…