Science.gov

Sample records for additional applications include

  1. Photoactive devices including porphyrinoids with coordinating additives

    DOEpatents

    Forrest, Stephen R; Zimmerman, Jeramy; Yu, Eric K; Thompson, Mark E; Trinh, Cong; Whited, Matthew; Diev, Vlacheslav

    2015-05-12

    Coordinating additives are included in porphyrinoid-based materials to promote intermolecular organization and improve one or more photoelectric characteristics of the materials. The coordinating additives are selected from fullerene compounds and organic compounds having free electron pairs. Combinations of different coordinating additives can be used to tailor the characteristic properties of such porphyrinoid-based materials, including porphyrin oligomers. Bidentate ligands are one type of coordinating additive that can form coordination bonds with a central metal ion of two different porphyrinoid compounds to promote porphyrinoid alignment and/or pi-stacking. The coordinating additives can shift the absorption spectrum of a photoactive material toward higher wavelengths, increase the external quantum efficiency of the material, or both.

  2. Constant-Pressure Combustion Charts Including Effects of Diluent Addition

    NASA Technical Reports Server (NTRS)

    Turner, L Richard; Bogart, Donald

    1949-01-01

    Charts are presented for the calculation of (a) the final temperatures and the temperature changes involved in constant-pressure combustion processes of air and in products of combustion of air and hydrocarbon fuels, and (b) the quantity of hydrocarbon fuels required in order to attain a specified combustion temperature when water, alcohol, water-alcohol mixtures, liquid ammonia, liquid carbon dioxide, liquid nitrogen, liquid oxygen, or their mixtures are added to air as diluents or refrigerants. The ideal combustion process and combustion with incomplete heat release from the primary fuel and from combustible diluents are considered. The effect of preheating the mixture of air and diluents and the effect of an initial water-vapor content in the combustion air on the required fuel quantity are also included. The charts are applicable only to processes in which the final mixture is leaner than stoichiometric and at temperatures where dissociation is unimportant. A chart is also included to permit the calculation of the stoichiometric ratio of hydrocarbon fuel to air with diluent addition. The use of the charts is illustrated by numerical examples.

  3. Additive manufacturing of glass for optical applications

    NASA Astrophysics Data System (ADS)

    Luo, Junjie; Gilbert, Luke J.; Bristow, Douglas A.; Landers, Robert G.; Goldstein, Jonathan T.; Urbas, Augustine M.; Kinzel, Edward C.

    2016-04-01

    Glasses including fused quartz have significant scientific and engineering applications including optics, communications, electronics, and hermetic seals. This paper investigates a filament fed process for Additive Manufacturing (AM) of fused quartz. Additive manufacturing has several potential benefits including increased design freedom, faster prototyping, and lower processing costs for small production volumes. However, current research in AM of glasses is limited and has focused on non-optical applications. Fused quartz is studied here because of its desirability for high-quality optics due to its high transmissivity and thermal stability. Fused quartz also has a higher working temperature than soda lime glass which poses a challenge for AM. In this work, fused quartz filaments are fed into a CO2 laser generated melt pool, smoothly depositing material onto the work piece. Single tracks are printed to explore the effects that different process parameters have on the morphology of printed fused quartz. A spectrometer is used to measure the thermal radiation incandescently emitted from the melt pool. Thin-walls are printed to study the effects of layer-to-layer height. Finally, a 3D fused quartz cube is printed using the newly acquired layer height and polished on each surface. The transmittance and index homogeneity of the polished cube are both measured. These results show that the filament fed process has the potential to print fused quartz with optical transparency and of index of refraction uniformity approaching bulk processed glass.

  4. [Additive Manufacturing and Its Medical Applications].

    PubMed

    Song, Zewen; Wang, Guohui; Gao, Qin; Zhu, Shaihong

    2015-04-01

    Additive manufacturing (AM) is a collection of technologies based on the layer-by-layer manufacturing. Characterized by its direct manufacturing and rapidity, it has been regarded by the Economist Journal as one of the key techniques which will trigger the third industry reformation. The present article, beginning with a brief introduction of the history of AM and the process of its major technologies, focuses on the advantages and disadvantages and medical applications of the technique.

  5. 30 CFR 250.1007 - What to include in applications.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Pipelines and Pipeline Rights-of-Way § 250.1007 What to include in applications. (a) Applications to install a lease term pipeline or for a pipeline right-of-way grant must be submitted in quadruplicate to the... pipeline. Each application must include the following: (1) Plat(s) drawn to a scale specified by...

  6. 37 CFR 2.86 - Application may include multiple classes.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... multiple classes. 2.86 Section 2.86 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK... include multiple classes. (a) In a single application, an applicant may apply to register the same mark for goods and/or services in multiple classes. The applicant must: (1) Specifically identify the...

  7. Thiol-addition reactions and their applications in thiol recognition.

    PubMed

    Yin, Caixia; Huo, Fangjun; Zhang, Jingjing; Martínez-Máñez, Ramón; Yang, Yutao; Lv, Haigang; Li, Sidian

    2013-07-21

    Because of the biological importance of thiols, the development of probes for thiols has been an active research area in recent years. In this review, we summarize the results of recent exciting reports regarding thiol-addition reactions and their applications in thiol recognition. The examples reported can be classified into four reaction types including 1,1, 1,2, 1,3, 1,4 addition reactions, according to their addition mechanisms, based on different Michael acceptors. In all cases, the reactions are coupled to color and/or emission changes, although some examples dealing with electrochemical recognition have also been included. The use of thiol-addition reactions is a very simple and straightforward procedure for the preparation of thiol-sensing probes.

  8. Additives

    NASA Technical Reports Server (NTRS)

    Smalheer, C. V.

    1973-01-01

    The chemistry of lubricant additives is discussed to show what the additives are chemically and what functions they perform in the lubrication of various kinds of equipment. Current theories regarding the mode of action of lubricant additives are presented. The additive groups discussed include the following: (1) detergents and dispersants, (2) corrosion inhibitors, (3) antioxidants, (4) viscosity index improvers, (5) pour point depressants, and (6) antifouling agents.

  9. Additive Manufacturing: Ensuring Quality for Spacecraft Applications

    NASA Technical Reports Server (NTRS)

    Swanson, Theodore; Stephenson, Timothy

    2014-01-01

    Reliable manufacturing requires that material properties and fabrication processes be well defined in order to insure that the manufactured parts meet specified requirements. While this issue is now relatively straightforward for traditional processes such as subtractive manufacturing and injection molding, this capability is still evolving for AM products. Hence, one of the principal challenges within AM is in qualifying and verifying source material properties and process control. This issue is particularly critical for applications in harsh environments and demanding applications, such as spacecraft.

  10. 38 CFR 21.8380 - Additional applicable regulations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Children of Vietnam Veterans and Veterans with Covered Service in Korea-Spina Bifida and Covered Birth Defects Additional Applicable Regulations § 21.8380 Additional applicable regulations. The...

  11. 38 CFR 21.8380 - Additional applicable regulations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Children of Vietnam Veterans and Veterans with Covered Service in Korea-Spina Bifida and Covered Birth Defects Additional Applicable Regulations § 21.8380 Additional applicable regulations. The...

  12. 38 CFR 21.8380 - Additional applicable regulations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Children of Vietnam Veterans and Veterans with Covered Service in Korea-Spina Bifida and Covered Birth Defects Additional Applicable Regulations § 21.8380 Additional applicable regulations. The...

  13. 38 CFR 21.8380 - Additional applicable regulations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Children of Vietnam Veterans and Veterans with Covered Service in Korea-Spina Bifida and Covered Birth Defects Additional Applicable Regulations § 21.8380 Additional applicable regulations. The...

  14. 38 CFR 17.255 - Applications for grants for programs which include construction projects.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... for programs which include construction projects. 17.255 Section 17.255 Pensions, Bonuses, and... Applications for grants for programs which include construction projects. In addition to the documents and... specifications for the construction project, and where applicable, sufficient explanations of...

  15. 38 CFR 17.255 - Applications for grants for programs which include construction projects.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... for programs which include construction projects. 17.255 Section 17.255 Pensions, Bonuses, and... Applications for grants for programs which include construction projects. In addition to the documents and... specifications for the construction project, and where applicable, sufficient explanations of...

  16. 38 CFR 17.255 - Applications for grants for programs which include construction projects.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... for programs which include construction projects. 17.255 Section 17.255 Pensions, Bonuses, and... Applications for grants for programs which include construction projects. In addition to the documents and... specifications for the construction project, and where applicable, sufficient explanations of...

  17. 38 CFR 17.255 - Applications for grants for programs which include construction projects.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... for programs which include construction projects. 17.255 Section 17.255 Pensions, Bonuses, and... Applications for grants for programs which include construction projects. In addition to the documents and... specifications for the construction project, and where applicable, sufficient explanations of...

  18. 38 CFR 17.255 - Applications for grants for programs which include construction projects.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... for programs which include construction projects. 17.255 Section 17.255 Pensions, Bonuses, and... Applications for grants for programs which include construction projects. In addition to the documents and... specifications for the construction project, and where applicable, sufficient explanations of...

  19. 34 CFR 636.10 - What must an application include?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What must an application include? 636.10 Section 636.10 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION URBAN COMMUNITY SERVICE PROGRAM How Does One Apply for an Award? §...

  20. 34 CFR 636.10 - What must an application include?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false What must an application include? 636.10 Section 636.10 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION URBAN COMMUNITY SERVICE PROGRAM How Does One Apply for an Award? §...

  1. 34 CFR 636.10 - What must an application include?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false What must an application include? 636.10 Section 636.10 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION URBAN COMMUNITY SERVICE PROGRAM How Does One Apply for an Award? §...

  2. 34 CFR 636.10 - What must an application include?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false What must an application include? 636.10 Section 636.10 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION URBAN COMMUNITY SERVICE PROGRAM How Does One Apply for an Award? §...

  3. 34 CFR 636.10 - What must an application include?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false What must an application include? 636.10 Section 636.10 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION URBAN COMMUNITY SERVICE PROGRAM How Does One Apply for an Award? §...

  4. 30 CFR 250.1007 - What to include in applications.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    .... Right-of-way grant applications must include an identification of the operator of the pipeline. Each... responsibility transfers between a producing operator and a transporting operator. (3) General information as follows: (i) Description of cathodic protection system. If pipeline anodes are to be used, specify...

  5. 30 CFR 250.1007 - What to include in applications.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    .... Right-of-way grant applications must include an identification of the operator of the pipeline. Each... responsibility transfers between a producing operator and a transporting operator. (3) General information as follows: (i) Description of cathodic protection system. If pipeline anodes are to be used, specify...

  6. 30 CFR 250.1007 - What to include in applications.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    .... Right-of-way grant applications must include an identification of the operator of the pipeline. Each... responsibility transfers between a producing operator and a transporting operator. (3) General information as follows: (i) Description of cathodic protection system. If pipeline anodes are to be used, specify...

  7. Additional records of metazoan parasites from Caribbean marine mammals, including genetically identified anisakid nematodes.

    PubMed

    Colón-Llavina, Marlene M; Mignucci-Giannoni, Antonio A; Mattiucci, Simonetta; Paoletti, Michela; Nascetti, Giuseppe; Williams, Ernest H

    2009-10-01

    Studies of marine mammal parasites in the Caribbean are scarce. An assessment for marine mammal endo- and ectoparasites from Puerto Rico and the Virgin Islands, but extending to other areas of the Caribbean, was conducted between 1989 and 1994. The present study complements the latter and enhances identification of anisakid nematodes using molecular markers. Parasites were collected from 59 carcasses of stranded cetaceans and manatees from 1994 to 2006, including Globicephala macrorhynchus, Kogia breviceps, Kogia sima, Lagenodelphis hosei, Mesoplodon densirostris, Peponocephala electra, Stenella longirostris, Steno bredanensis, Trichechus manatus. Tursiops truncatus, and Ziphius cavirostris. Sixteen species of endoparasitic helminthes were morphologically identified, including two species of acanthocephalans (Bolbosoma capitatum, Bolbosoma vasculosum), nine species of nematodes (Anisakis sp., Anisakis brevispiculata, Anisakis paggiae, Anisakis simplex, Anisakis typica, Anisakis ziphidarium, Crassicauda anthonyi, Heterocheilus tunicatus, Pseudoterranova ceticola), two species of cestodes (Monorygma grimaldi, Phyllobothrium delphini), and three species of trematodes (Chiorchis groschafti, Pulmonicola cochleotrema, Monoligerum blairi). The nematodes belonging to the genus Anisakis recovered in some stranded animals were genetically identified to species level based on their sequence analysis of mitochondrial DNA (629 bp of mtDNA cox 2). A total of five new host records and six new geographic records are presented. PMID:19582477

  8. Additional records of metazoan parasites from Caribbean marine mammals, including genetically identified anisakid nematodes.

    PubMed

    Colón-Llavina, Marlene M; Mignucci-Giannoni, Antonio A; Mattiucci, Simonetta; Paoletti, Michela; Nascetti, Giuseppe; Williams, Ernest H

    2009-10-01

    Studies of marine mammal parasites in the Caribbean are scarce. An assessment for marine mammal endo- and ectoparasites from Puerto Rico and the Virgin Islands, but extending to other areas of the Caribbean, was conducted between 1989 and 1994. The present study complements the latter and enhances identification of anisakid nematodes using molecular markers. Parasites were collected from 59 carcasses of stranded cetaceans and manatees from 1994 to 2006, including Globicephala macrorhynchus, Kogia breviceps, Kogia sima, Lagenodelphis hosei, Mesoplodon densirostris, Peponocephala electra, Stenella longirostris, Steno bredanensis, Trichechus manatus. Tursiops truncatus, and Ziphius cavirostris. Sixteen species of endoparasitic helminthes were morphologically identified, including two species of acanthocephalans (Bolbosoma capitatum, Bolbosoma vasculosum), nine species of nematodes (Anisakis sp., Anisakis brevispiculata, Anisakis paggiae, Anisakis simplex, Anisakis typica, Anisakis ziphidarium, Crassicauda anthonyi, Heterocheilus tunicatus, Pseudoterranova ceticola), two species of cestodes (Monorygma grimaldi, Phyllobothrium delphini), and three species of trematodes (Chiorchis groschafti, Pulmonicola cochleotrema, Monoligerum blairi). The nematodes belonging to the genus Anisakis recovered in some stranded animals were genetically identified to species level based on their sequence analysis of mitochondrial DNA (629 bp of mtDNA cox 2). A total of five new host records and six new geographic records are presented.

  9. 21 CFR 1311.302 - Additional application provider requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Additional application provider requirements. 1311.302 Section 1311.302 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE... than five business days after discovery, that the application should not be used to issue or...

  10. 21 CFR 1311.302 - Additional application provider requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Additional application provider requirements. 1311.302 Section 1311.302 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE... than five business days after discovery, that the application should not be used to issue or...

  11. 21 CFR 1311.302 - Additional application provider requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Additional application provider requirements. 1311.302 Section 1311.302 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE... than five business days after discovery, that the application should not be used to issue or...

  12. 21 CFR 1311.302 - Additional application provider requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Additional application provider requirements. 1311.302 Section 1311.302 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE... than five business days after discovery, that the application should not be used to issue or...

  13. 47 CFR 51.223 - Application of additional requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Application of additional requirements. 51.223 Section 51.223 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) INTERCONNECTION Obligations of All Local Exchange Carriers § 51.223 Application of...

  14. 10 CFR 70.65 - Additional content of applications.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Additional content of applications. 70.65 Section 70.65 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DOMESTIC LICENSING OF SPECIAL NUCLEAR MATERIAL Additional Requirements for Certain Licensees Authorized To Possess a Critical Mass of Special...

  15. The Application and Development of an Addition Goal Sketch

    ERIC Educational Resources Information Center

    Baroody, Arthur J.; Brach, Catherine; Tai, Yu-chi

    2006-01-01

    A schema based view of addition development is compared with Siegler's latest strategy-choice model, which includes an addition goal sketch (a basic understanding of "the goals and causal relations" of addition; Siegler & Crowley, 1994, p. 196). This metacognitive component in the latter model is presumed to develop as a child practices a basic…

  16. 40 CFR 260.23 - Petitions to amend 40 CFR part 273 to include additional hazardous wastes.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Petitions to amend 40 CFR part 273 to include additional hazardous wastes. 260.23 Section 260.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) HAZARDOUS WASTE MANAGEMENT SYSTEM: GENERAL...

  17. 78 FR 67369 - National Vaccine Injury Compensation Program: Addition to the Vaccine Injury Table to Include All...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-12

    ... the category for new vaccines on the Table. See 70 FR 19092. Subsequently, the Secretary engaged in...). See 76 FR 36367. Since that time, quadrivalent influenza vaccines (meaning that they contain four...: Addition to the Vaccine Injury Table to Include All Vaccines Against Seasonal Influenza AGENCY:...

  18. 77 FR 1073 - Privacy Act of 1974; Report of an Altered System of Records, Including Addition of Routine Uses...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-09

    ... HUMAN SERVICES Food and Drug Administration Privacy Act of 1974; Report of an Altered System of Records, Including Addition of Routine Uses to an Existing System of Records; Bioresearch Monitoring Information System AGENCY: Food and Drug Administration, HHS. ACTION: Notice of an altered system of records....

  19. Major histocompatibility complex harbors widespread genotypic variability of non-additive risk of rheumatoid arthritis including epistasis

    PubMed Central

    Wei, Wen-Hua; Bowes, John; Plant, Darren; Viatte, Sebastien; Yarwood, Annie; Massey, Jonathan; Worthington, Jane; Eyre, Stephen

    2016-01-01

    Genotypic variability based genome-wide association studies (vGWASs) can identify potentially interacting loci without prior knowledge of the interacting factors. We report a two-stage approach to make vGWAS applicable to diseases: firstly using a mixed model approach to partition dichotomous phenotypes into additive risk and non-additive environmental residuals on the liability scale and secondly using the Levene’s (Brown-Forsythe) test to assess equality of the residual variances across genotype groups per marker. We found widespread significant (P < 2.5e-05) vGWAS signals within the major histocompatibility complex (MHC) across all three study cohorts of rheumatoid arthritis. We further identified 10 epistatic interactions between the vGWAS signals independent of the MHC additive effects, each with a weak effect but jointly explained 1.9% of phenotypic variance. PTPN22 was also identified in the discovery cohort but replicated in only one independent cohort. Combining the three cohorts boosted power of vGWAS and additionally identified TYK2 and ANKRD55. Both PTPN22 and TYK2 had evidence of interactions reported elsewhere. We conclude that vGWAS can help discover interacting loci for complex diseases but require large samples to find additional signals. PMID:27109064

  20. 36 CFR 251.61 - Applications for new, changed, or additional uses or area.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., or additional uses or area. 251.61 Section 251.61 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE LAND USES Special Uses § 251.61 Applications for new, changed, or additional uses..., or additional uses or area, including any changes that involve any activity that has an impact on...

  1. 36 CFR 251.61 - Applications for new, changed, or additional uses or area.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., or additional uses or area. 251.61 Section 251.61 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE LAND USES Special Uses § 251.61 Applications for new, changed, or additional uses..., or additional uses or area, including any changes that involve any activity that has an impact on...

  2. 34 CFR 645.21 - What assurances must an applicant include in an application?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What assurances must an applicant include in an application? 645.21 Section 645.21 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION UPWARD BOUND PROGRAM How Does One Apply for An Award? § 645.21 What assurances...

  3. 34 CFR 645.21 - What assurances must an applicant include in an application?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false What assurances must an applicant include in an application? 645.21 Section 645.21 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION UPWARD BOUND PROGRAM How Does...

  4. Applications of Metal Additive Manufacturing in Veterinary Orthopedic Surgery

    NASA Astrophysics Data System (ADS)

    Harrysson, Ola L. A.; Marcellin-Little, Denis J.; Horn, Timothy J.

    2015-03-01

    Veterinary medicine has undergone a rapid increase in specialization over the last three decades. Veterinarians now routinely perform joint replacement, neurosurgery, limb-sparing surgery, interventional radiology, radiation therapy, and other complex medical procedures. Many procedures involve advanced imaging and surgical planning. Evidence-based medicine has also become part of the modus operandi of veterinary clinicians. Modeling and additive manufacturing can provide individualized or customized therapeutic solutions to support the management of companion animals with complex medical problems. The use of metal additive manufacturing is increasing in veterinary orthopedic surgery. This review describes and discusses current and potential applications of metal additive manufacturing in veterinary orthopedic surgery.

  5. 20 CFR 416.263 - No additional application needed.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false No additional application needed. 416.263 Section 416.263 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

  6. 20 CFR 416.263 - No additional application needed.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false No additional application needed. 416.263 Section 416.263 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

  7. 25 CFR 227.7 - Additional information from applicant.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Additional information from applicant. 227.7 Section 227.7 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF CERTAIN LANDS IN WIND RIVER INDIAN RESERVATION, WYOMING, FOR OIL AND GAS MINING How to Acquire Leases §...

  8. 25 CFR 227.7 - Additional information from applicant.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Additional information from applicant. 227.7 Section 227.7 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF CERTAIN LANDS IN WIND RIVER INDIAN RESERVATION, WYOMING, FOR OIL AND GAS MINING How to Acquire...

  9. 25 CFR 227.7 - Additional information from applicant.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Additional information from applicant. 227.7 Section 227.7 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF CERTAIN LANDS IN WIND RIVER INDIAN RESERVATION, WYOMING, FOR OIL AND GAS MINING How to Acquire...

  10. 25 CFR 227.7 - Additional information from applicant.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Additional information from applicant. 227.7 Section 227.7 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF CERTAIN LANDS IN WIND RIVER INDIAN RESERVATION, WYOMING, FOR OIL AND GAS MINING How to Acquire...

  11. 25 CFR 227.7 - Additional information from applicant.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Additional information from applicant. 227.7 Section 227.7 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF CERTAIN LANDS IN WIND RIVER INDIAN RESERVATION, WYOMING, FOR OIL AND GAS MINING How to Acquire...

  12. An Optical Additive Solc Filter for Deep Ultraviolet Applications

    NASA Astrophysics Data System (ADS)

    Manka, Charles; Nikitin, Sergei

    2008-10-01

    A number of optical applications in the deep ultra violet (DUV) range have limitations due to the absence of simple and reliable optical notch filters. This is important for resonant Raman applications that employ frequency agile laser illumination at many sequential DUV wavelengths. Our filter is based on widely known birefringent filter design originally proposed by Solc [I. Solc ``Birefringent chain filters'' JOSA 55, p.621 (1965)]. Rather than the transmission filter design of Solc, the additive Solc filter (ASF) described here is suitable for narrow-line rejection (< 1 nm), as dictated by the requirements of UVRR and other applications. We have designed and constructed such a filter and present test results. Finally, we present a design which allows fiber delivery of DUV illumination wavelengths, rejects the quartz Raman lines generated in the fiber, but then rejects the backscattered unshifted light from a target and passes the Raman lines generated by the target material.

  13. Imaging requirements for medical applications of additive manufacturing.

    PubMed

    Huotilainen, Eero; Paloheimo, Markku; Salmi, Mika; Paloheimo, Kaija-Stiina; Björkstrand, Roy; Tuomi, Jukka; Markkola, Antti; Mäkitie, Antti

    2014-02-01

    Additive manufacturing (AM), formerly known as rapid prototyping, is steadily shifting its focus from industrial prototyping to medical applications as AM processes, bioadaptive materials, and medical imaging technologies develop, and the benefits of the techniques gain wider knowledge among clinicians. This article gives an overview of the main requirements for medical imaging affected by needs of AM, as well as provides a brief literature review from existing clinical cases concentrating especially on the kind of radiology they required. As an example application, a pair of CT images of the facial skull base was turned into 3D models in order to illustrate the significance of suitable imaging parameters. Additionally, the model was printed into a preoperative medical model with a popular AM device. Successful clinical cases of AM are recognized to rely heavily on efficient collaboration between various disciplines - notably operating surgeons, radiologists, and engineers. The single main requirement separating tangible model creation from traditional imaging objectives such as diagnostics and preoperative planning is the increased need for anatomical accuracy in all three spatial dimensions, but depending on the application, other specific requirements may be present as well. This article essentially intends to narrow the potential communication gap between radiologists and engineers who work with projects involving AM by showcasing the overlap between the two disciplines.

  14. 30 CFR 203.63 - Does my application have to include all leases in the field?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... and Expansion Projects § 203.63 Does my application have to include all leases in the field? (a) For... project or an expansion project, your application does not have to include all leases in the field....

  15. A new application for food customization with additive manufacturing technologies

    NASA Astrophysics Data System (ADS)

    Serenó, L.; Vallicrosa, G.; Delgado, J.; Ciurana, J.

    2012-04-01

    Additive Manufacturing (AM) technologies have emerged as a freeform approach capable of producing almost any complete three dimensional (3D) objects from computer-aided design (CAD) data by successively adding material layer by layer. Despite the broad range of possibilities, commercial AM technologies remain complex and expensive, making them suitable only for niche applications. The developments of the Fab@Home system as an open AM technology discovered a new range of possibilities of processing different materials such as edible products. The main objective of this work is to analyze and optimize the manufacturing capacity of this system when producing 3D edible objects. A new heated syringe deposition tool was developed and several process parameters were optimized to adapt this technology to consumers' needs. The results revealed in this study show the potential of this system to produce customized edible objects without qualified personnel knowledge, therefore saving manufacturing costs compared to traditional technologies.

  16. Economic incentives for additional critical experimentation applicable to fuel dissolution

    SciTech Connect

    Mincey, J.F.; Primm, R.T. III; Waltz, W.R.

    1981-01-01

    Fuel dissolution operations involving soluble absorbers for criticality control are among the most difficult to establish economical subcritical limits. The paucity of applicable experimental data can significantly hinder a precise determination of a bias in the method chosen for calculation of the required soluble absorber concentration. Resorting to overly conservative bias estimates can result in excessive concentrations of soluble absorbers. Such conservatism can be costly, especially if soluble absorbers are used in a throw-away fashion. An economic scoping study is presented which demonstrates that additional critical experimentation will likely lead to reductions in the soluble absorber (i.e., gadolinium) purchase costs for dissolution operations. The results indicate that anticipated savings maybe more than enough to pay for the experimental costs.

  17. Performance of portland limestone cements: Cements designed to be more sustainable that include up to 15% limestone addition

    NASA Astrophysics Data System (ADS)

    Barrett, Timothy J.

    In 2009, ASTM and AASHTO permitted the use of up to 5% interground limestone in ordinary portland cement (OPC) as a part of a change to ASTM C150/AASHTO M85. When this work was initiated a new proposal was being discussed that would enable up to 15% interground limestone cement to be considered in ASTM C595/AASHTO M234. This work served to provide rapid feedback to the state department of transportation and concrete industry for use in discussions regarding these specifications. Since the time this work was initiated, ASTM C595/AASHTO M234 was passed (2012c) and PLCs are now able to be specified, however they are still not widely used. The proposal for increasing the volume of limestone that would be permitted to be interground in cement is designed to enable more sustainable construction, which may significantly reduce the CO2 that is embodied in the built infrastructure while also extending the life of cement quarries. Research regarding the performance of cements with interground limestone has been conducted by the cement industry since these cements became widely used in Europe over three decades ago, however this work focuses on North American Portland Limestone Cements (PLCs) which are specifically designed to achieve similar performance as the OPCs they replace.This thesis presents a two-phase study in which the potential for application of cements containing limestone was assessed. The first phase of this study utilized a fundamental approach to determine whether cement with up to 15% of interground or blended limestone can be used as a direct substitute to ordinary portland cement. The second phase of the study assessed the concern of early age shrinkage and cracking potential when using PLCs, as these cements are typically ground finer than their OPC counterparts. For the first phase of the study, three commercially produced PLCs were obtained and compared to three commercially produced OPCs made from the same clinker. An additional cement was tested

  18. Performance of portland limestone cements: Cements designed to be more sustainable that include up to 15% limestone addition

    NASA Astrophysics Data System (ADS)

    Barrett, Timothy J.

    In 2009, ASTM and AASHTO permitted the use of up to 5% interground limestone in ordinary portland cement (OPC) as a part of a change to ASTM C150/AASHTO M85. When this work was initiated a new proposal was being discussed that would enable up to 15% interground limestone cement to be considered in ASTM C595/AASHTO M234. This work served to provide rapid feedback to the state department of transportation and concrete industry for use in discussions regarding these specifications. Since the time this work was initiated, ASTM C595/AASHTO M234 was passed (2012c) and PLCs are now able to be specified, however they are still not widely used. The proposal for increasing the volume of limestone that would be permitted to be interground in cement is designed to enable more sustainable construction, which may significantly reduce the CO2 that is embodied in the built infrastructure while also extending the life of cement quarries. Research regarding the performance of cements with interground limestone has been conducted by the cement industry since these cements became widely used in Europe over three decades ago, however this work focuses on North American Portland Limestone Cements (PLCs) which are specifically designed to achieve similar performance as the OPCs they replace.This thesis presents a two-phase study in which the potential for application of cements containing limestone was assessed. The first phase of this study utilized a fundamental approach to determine whether cement with up to 15% of interground or blended limestone can be used as a direct substitute to ordinary portland cement. The second phase of the study assessed the concern of early age shrinkage and cracking potential when using PLCs, as these cements are typically ground finer than their OPC counterparts. For the first phase of the study, three commercially produced PLCs were obtained and compared to three commercially produced OPCs made from the same clinker. An additional cement was tested

  19. Application of Additive Manufacturing in Oral and Maxillofacial Surgery.

    PubMed

    Farré-Guasch, Elisabet; Wolff, Jan; Helder, Marco N; Schulten, Engelbert A J M; Forouzanfar, Tim; Klein-Nulend, Jenneke

    2015-12-01

    Additive manufacturing is the process of joining materials to create objects from digital 3-dimensional (3D) model data, which is a promising technology in oral and maxillofacial surgery. The management of lost craniofacial tissues owing to congenital abnormalities, trauma, or cancer treatment poses a challenge to oral and maxillofacial surgeons. Many strategies have been proposed for the management of such defects, but autogenous bone grafts remain the gold standard for reconstructive bone surgery. Nevertheless, cell-based treatments using adipose stem cells combined with osteoconductive biomaterials or scaffolds have become a promising alternative to autogenous bone grafts. Such treatment protocols often require customized 3D scaffolds that fulfill functional and esthetic requirements, provide adequate blood supply, and meet the load-bearing requirements of the head. Currently, such customized 3D scaffolds are being manufactured using additive manufacturing technology. In this review, 2 of the current and emerging modalities for reconstruction of oral and maxillofacial bone defects are highlighted and discussed, namely human maxillary sinus floor elevation as a valid model to test bone tissue-engineering approaches enabling the application of 1-step surgical procedures and seeding of Good Manufacturing Practice-level adipose stem cells on computer-aided manufactured scaffolds to reconstruct large bone defects in a 2-step surgical procedure, in which cells are expanded ex vivo and seeded on resorbable scaffolds before implantation. Furthermore, imaging-guided tissue-engineering technologies to predetermine the surgical location and to facilitate the manufacturing of custom-made implants that meet the specific patient's demands are discussed. The potential of tissue-engineered constructs designed for the repair of large oral and maxillofacial bone defects in load-bearing situations in a 1-step surgical procedure combining these 2 innovative approaches is

  20. The Application of Powder Rheology in Additive Manufacturing

    NASA Astrophysics Data System (ADS)

    Clayton, Jamie; Millington-Smith, Doug; Armstrong, Brian

    2015-03-01

    Additive manufacturing (AM) is sensitive to powder variability when applying fine layers in a uniform manner. This demands a high degree of consistency and repeatability in the feedstock. Particle size is often used as a critical quality attribute, but this is not sufficient to fully qualify a feedstock. Indeed, it is inadequate to suggest that any parameter from a single test, e.g., Hall flowmeter or Hausner ratio, can comprehensively describe a powder's characteristics. This article uses four case studies to demonstrate the limitations of single parameter characterization and how the rheological properties of several metal powders used in AM applications are used to establish in-process performance. In the first study, the significantly reduced permeability and increased specific energy of a one batch of powder demonstrate a clear link to poor layer uniformity. The second study investigates the impact of metal powder manufacturing methods and suppliers, and it shows how shear properties alone cannot be relied on to identify properties that influence the process. The effect of additives on the processability of polymer blends used in AM is also evaluated, and the results show that even small quantities can have a significant effect on the permeability and basic flowability energy of feedstocks. The final study demonstrates the how rheological measurements can be used to identify the optimum blend of fresh and used material when reusing metal powders to manufacture components. These case studies illustrate the ability of a modern powder rheometer to detect minor variations in powders that are directly relevant to performance in AM processes in a way that traditional characterization methods cannot.

  1. 21 CFR 1311.302 - Additional application provider requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... part, the application provider must notify practitioners or pharmacies that use the application as soon... practitioners or pharmacies with updates to any issue that makes the application non-compliant with the... practitioner or pharmacy may use the application to issue or process electronic controlled...

  2. 36 CFR 1290.4 - Types of materials included in scope of assassination record and additional records and information.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION JFK ASSASSINATION RECORDS... COLLECTION ACT OF 1992 (JFK ACT) § 1290.4 Types of materials included in scope of assassination record and... information includes, for purposes of interpreting and implementing the JFK Act: (a) Papers, maps, and...

  3. 36 CFR 1290.4 - Types of materials included in scope of assassination record and additional records and information.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION JFK ASSASSINATION RECORDS... COLLECTION ACT OF 1992 (JFK ACT) § 1290.4 Types of materials included in scope of assassination record and... information includes, for purposes of interpreting and implementing the JFK Act: (a) Papers, maps, and...

  4. 36 CFR 1290.4 - Types of materials included in scope of assassination record and additional records and information.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION JFK ASSASSINATION RECORDS... COLLECTION ACT OF 1992 (JFK ACT) § 1290.4 Types of materials included in scope of assassination record and... information includes, for purposes of interpreting and implementing the JFK Act: (a) Papers, maps, and...

  5. 36 CFR 1290.4 - Types of materials included in scope of assassination record and additional records and information.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION JFK ASSASSINATION RECORDS... COLLECTION ACT OF 1992 (JFK ACT) § 1290.4 Types of materials included in scope of assassination record and... information includes, for purposes of interpreting and implementing the JFK Act: (a) Papers, maps, and...

  6. 36 CFR 1290.4 - Types of materials included in scope of assassination record and additional records and information.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION JFK ASSASSINATION RECORDS... COLLECTION ACT OF 1992 (JFK ACT) § 1290.4 Types of materials included in scope of assassination record and... information includes, for purposes of interpreting and implementing the JFK Act: (a) Papers, maps, and...

  7. 43 CFR 3273.15 - What must I include in my site license application?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... site license application must include: (a) A description of the boundaries of the land applied for, as... range, or by approved protraction surveys, if applicable; (b) The affected acreage; (c) The filing...

  8. 34 CFR 607.12 - What must be included in cooperative arrangement grant applications?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... arrangement. (2) The application must include the names of each participating institution, the role of each... comprehensive development plan at a lower cost. (4) The name of the applicant for the group that is...

  9. Additively Manufactured Combustion Devices Components for LOX/Methane Applications

    NASA Technical Reports Server (NTRS)

    Greene, Sandra Elam; Protz, Christopher; Garcia, Chance; Goodman, Dwight; Baker, Kevin

    2016-01-01

    Marshall Space Flight Center (MSFC) has designed, fabricated, and hot-fire tested a variety of successful injectors, chambers, and igniters for potential liquid oxygen (LOX) and methane (CH4) systems since 2005. The most recent efforts have focused on components with additive manufacturing (AM) to include unique design features, minimize joints, and reduce final machining efforts. Inconel and copper alloys have been used with AM processes to produce a swirl coaxial injector and multiple methane cooled thrust chambers. The initial chambers included unique thermocouple ports for measuring local coolant channel temperatures along the length of the chamber. Results from hot-fire testing were used to anchor thermal models and generate a regeneratively cooled thruster for a 4,000 lbf LOX/CH4 engine. The completed thruster will be hot-fire tested in the summer of 2016 at MSFC. The thruster design can also be easily scaled and used on a 25,000 lbf engine. To further support the larger engine design, an AM gas generator injector has been designed. Hot-fire testing on this injector is planned for the summer of 2016 at MSFC.

  10. Applications for Gradient Metal Alloys Fabricated Using Additive Manufacturing

    NASA Technical Reports Server (NTRS)

    Hofmann, Douglas C.; Borgonia, John Paul C.; Dillon, Robert P.; Suh, Eric J.; Mulder, jerry L.; Gardner, Paul B.

    2013-01-01

    Recently, additive manufacturing (AM) techniques have been developed that may shift the paradigm of traditional metal production by allowing complex net-shaped hardware to be built up layer-by-layer, rather than being machined from a billet. The AM process is ubiquitous with polymers due to their low melting temperatures, fast curing, and controllable viscosity, and 3D printers are widely available as commercial or consumer products. 3D printing with metals is inherently more complicated than with polymers due to their higher melting temperatures and reactivity with air, particularly when heated or molten. The process generally requires a high-power laser or other focused heat source, like an electron beam, for precise melting and deposition. Several promising metal AM techniques have been developed, including laser deposition (also called laser engineered net shaping or LENS® and laser deposition technology (LDT)), direct metal laser sintering (DMLS), and electron beam free-form (EBF). These machines typically use powders or wire feedstock that are melted and deposited using a laser or electron beam. Complex net-shape parts have been widely demonstrated using these (and other) AM techniques and the process appears to be a promising alternative to machining in some cases. Rather than simply competing with traditional machining for cost and time savings, the true advantage of AM involves the fabrication of hardware that cannot be produced using other techniques. This could include parts with "blind" features (like foams or trusses), parts that are difficult to machine conventionally, or parts made from materials that do not exist in bulk forms. In this work, the inventors identify that several AM techniques can be used to develop metal parts that change composition from one location in the part to another, allowing for complete control over the mechanical or physical properties. This changes the paradigm for conventional metal fabrication, which relies on an

  11. 78 FR 51265 - 30-Day Notice of Proposed Information Collection: Application for Additional Visa Pages or...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-20

    ... Notice of Proposed Information Collection: Application for Additional Visa Pages or Miscellaneous...: Title of Information Collection: Application for Additional Visa Pages or Miscellaneous Passport... applies for the addition of visa pages to that passport, the Department must confirm the...

  12. 7 CFR 984.437 - Methods for proposing names of additional candidates to be included on walnut growers' nomination...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... to be included on walnut growers' nomination ballots. 984.437 Section 984.437 Agriculture Regulations... Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE WALNUTS GROWN IN CALIFORNIA Administrative... walnut growers' nomination ballots. (a) With regard to Board grower member positions specified in §...

  13. 7 CFR 984.437 - Methods for proposing names of additional candidates to be included on walnut growers' nomination...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... to be included on walnut growers' nomination ballots. 984.437 Section 984.437 Agriculture Regulations... Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE WALNUTS GROWN IN CALIFORNIA Administrative... walnut growers' nomination ballots. (a) With regard to Board grower member positions specified in §...

  14. 7 CFR 984.437 - Methods for proposing names of additional candidates to be included on walnut growers' nomination...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... to be included on walnut growers' nomination ballots. 984.437 Section 984.437 Agriculture Regulations... Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE WALNUTS GROWN IN CALIFORNIA Administrative... walnut growers' nomination ballots. (a) With regard to Board grower member positions specified in §...

  15. 7 CFR 984.437 - Methods for proposing names of additional candidates to be included on walnut growers' nomination...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... to be included on walnut growers' nomination ballots. 984.437 Section 984.437 Agriculture Regulations... ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE WALNUTS GROWN IN CALIFORNIA Administrative... walnut growers' nomination ballots. (a) With regard to Board grower member positions specified in §...

  16. 7 CFR 984.437 - Methods for proposing names of additional candidates to be included on walnut growers' nomination...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... to be included on walnut growers' nomination ballots. 984.437 Section 984.437 Agriculture Regulations... ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE WALNUTS GROWN IN CALIFORNIA Administrative... walnut growers' nomination ballots. (a) With regard to Board grower member positions specified in §...

  17. Autoclavable addition polyimides for 371 C composite applications

    NASA Technical Reports Server (NTRS)

    Vannucci, R. D.; Malarik, D.; Papadopoulos, D.; Waters, J.

    1990-01-01

    Studies were conducted to improve the thermo-oxidative stability (TOS) of PMR type polyimides by the substitution of para-aminostyrene (PAS) for the nadic ester endcap in second generation PMR polyimides (PMR-2). The nadic endcap which provides the PMR polyimides with their relative ease of fabrication, both by limiting the molecular weight of the prepolymer and by undergoing the final addition cure without volatiles, is also the weak link with regard to TOS. A polyimide formulated with PAS endcaps, called V-CAP, utilizes a two step reaction sequence similar to that of the PMR polyimides and can be easily autoclave molded into low void composite materials. Resin studies included two formulations of both PMR-2 and V-CAP, corresponding to n = 9 and n = 14 prepolymer stoichiometry. Unidirectional reinforced T40R graphite fiber laminates were fabricated from each of the resins was post-cured in either air at 385 C or nitrogen at 400 C. Composite specimens were aged in air at 371 C and mechanical properties were measured at 371 C before and after exposure.

  18. Autoclavable addition polyimides for 371 C composite applications

    NASA Technical Reports Server (NTRS)

    Vannucci, R. D.; Malarik, D. C.; Papadapoulos, D. S.; Waters, J. F.

    1990-01-01

    Studies were conducted to improve the thermo-oxidative stability (TOS) of PMR type polyimides by the substitution of para-aminostyrene (PAS) for the nadic ester endcap in second generation PMR polyimides (PMR-2). The nadic endcap which provides the PMR polyimides with their relative ease of fabrication, both by limiting the molecular weight of the prepolymer and by undergoing the final addition cure without volatiles, is also the weak link with regard to TOS. A polyimide formulated with PAS endcaps, called V-CAP, utilizes a two step reaction sequence similar to that of the PMR polyimides and can be easily autoclave molded into low void composite materials. Resin studies included two formulations of both PMR-2 and V-CAP, corresponding to n=9 and n=14 prepolymer stoichiometry. Unidirectional reinforced T40R graphite fiber laminates were fabricated from each of the resins was post-cured in either air at 385 C or nitrogen at 400 C. Composite specimens were aged in air at 371 C and mechanical properties were measured at 371 C before and after exposure.

  19. 45 CFR 2522.570 - What information on performance measures must my grant application include?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false What information on performance measures must my grant application include? 2522.570 Section 2522.570 Public Welfare Regulations Relating to Public... information on performance measures must my grant application include? You must submit all of the following...

  20. 40 CFR 270.110 - What must I include in my application for a RAP?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... for a RAP? 270.110 Section 270.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Remedial Action Plans (RAPs) Applying for A Rap § 270.110 What must I include in my application for a RAP? You must include the following information in your application for a RAP: (a) The name, address,...

  1. 40 CFR 270.110 - What must I include in my application for a RAP?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... for a RAP? 270.110 Section 270.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Remedial Action Plans (RAPs) Applying for A Rap § 270.110 What must I include in my application for a RAP? You must include the following information in your application for a RAP: (a) The name, address,...

  2. 40 CFR 270.110 - What must I include in my application for a RAP?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... for a RAP? 270.110 Section 270.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Remedial Action Plans (RAPs) Applying for A Rap § 270.110 What must I include in my application for a RAP? You must include the following information in your application for a RAP: (a) The name, address,...

  3. 40 CFR 270.110 - What must I include in my application for a RAP?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... for a RAP? 270.110 Section 270.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Remedial Action Plans (RAPs) Applying for A Rap § 270.110 What must I include in my application for a RAP? You must include the following information in your application for a RAP: (a) The name, address,...

  4. 40 CFR 270.110 - What must I include in my application for a RAP?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... for a RAP? 270.110 Section 270.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Remedial Action Plans (RAPs) Applying for A Rap § 270.110 What must I include in my application for a RAP? You must include the following information in your application for a RAP: (a) The name, address,...

  5. 38 CFR 21.6380 - Additional applicable Chapter 31 regulations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Chapter 31 regulations. 21.6380 Section 21.6380 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF... applicable Chapter 31 regulations. The following regulations are applicable to veterans pursuing the vocational training under this program in the same manner as they apply to 38 U.S.C. chapter 31: §...

  6. Uranium hydrogeochemical and stream sediment reconnaissance of the Newcastle NTMS quadrangle, Wyoming, including concentrations of forty-two additional elements

    SciTech Connect

    Goff, S.J.; Sandoval, W.F.; Gallimore, D.L.; Talcott, C.L.; Martinez, R.G.; Minor, M.E.; Mills, C.F.

    1980-06-01

    During the summer and fall of 1977, 533 water and 1226 sediment samples were collected from 1740 locations within the 18,000 km/sup 2/ area of the Newcastle quadrangle, Wyoming. Water samples were collected from wells and springs; sediment samples were collected from stream channels and from springs. Each water sample was analyzed for uranium, and each sediment sample was analyzed for 43 elements, including uranium and thorium. Uranium concentrations in water samples range from below the detection limit of 0.02 ppB to 702.26 ppB and have a median of 1.73 ppB and a mean of 11.76 ppB. Water samples containing high uranium concentrations (>20 ppB) generally are associated with known uranium mining activity or units known to be uranium bearing. About one-third of the water samples containing high uranium concentrations were collected from locations within the Pumpkin Buttes and Turnercrest-Ross Districts. Nearly half of the water samples containing high uranium concentrations were collected from locations just west of the Monument Hill and Highland Flats-Box Creek Districts. Similar anomalous uranium concentrations in this region have been reported updip from Exxon's Highland uranium deposits. High uranium concentrations were also found associated with the Lance Creek-Old Woman Anticline District.

  7. Hybrid Additive Manufacturing Technologies - An Analysis Regarding Potentials and Applications

    NASA Astrophysics Data System (ADS)

    Merklein, Marion; Junker, Daniel; Schaub, Adam; Neubauer, Franziska

    Imposing the trend of mass customization of lightweight construction in industry, conventional manufacturing processes like forming technology and chipping production are pushed to their limits for economical manufacturing. More flexible processes are needed which were developed by the additive manufacturing technology. This toolless production principle offers a high geometrical freedom and an optimized utilization of the used material. Thus load adjusted lightweight components can be produced in small lot sizes in an economical way. To compensate disadvantages like inadequate accuracy and surface roughness hybrid machines combining additive and subtractive manufacturing are developed. Within this paper the principles of mainly used additive manufacturing processes of metals and their possibility to be integrated into a hybrid production machine are summarized. It is pointed out that in particular the integration of deposition processes into a CNC milling center supposes high potential for manufacturing larger parts with high accuracy. Furthermore the combination of additive and subtractive manufacturing allows the production of ready to use products within one single machine. Additionally actual research for the integration of additive manufacturing processes into the production chain will be analyzed. For the long manufacturing time of additive production processes the combination with conventional manufacturing processes like sheet or bulk metal forming seems an effective solution. Especially large volumes can be produced by conventional processes. In an additional production step active elements can be applied by additive manufacturing. This principle is also investigated for tool production to reduce chipping of the high strength material used for forming tools. The aim is the addition of active elements onto a geometrical simple basis by using Laser Metal Deposition. That process allows the utilization of several powder materials during one process what

  8. Uranium hydrogeochemical and stream sediment reconnaissance of the Newcastle NTMS Quadrangle, Wyoming, including concentrations of forty-two additional elements

    SciTech Connect

    Goff, S.J.; Sandoval, W.F.; Gallimore, D.L.; Talcott, C.L.; Martinez, R.G.; Minor, M.E.; Mills, C.F.

    1980-06-01

    Water and sediment samples were collected and each water sample was analyzed for U, and each sediment sample was analyzed for 43 elements, including U and Th. Uranium concentrations in water samples range from below the detection limit of 0.02 ppB to 702.26 ppB and have a median of 1.73 ppB and a mean of 11.76 ppB. Water samples containing high uranium concentrations generally are associated with known uranium mining activity or units known to be uranium bearing. About one-third of the water samples containing high uranium concentrations were collected from locations within the Pumpkin Buttes and Turnercrest-Ross Districts. Nearly half of the water samples containing high uranium concentrations were collected from locations just west of the Monument Hill and Highland Flats-Box Creek Districts. Similar anomalous uranium concentrations in this region have been reported updip from Exxon's Highland uranium deposits. High uranium concentrations were also found associated with the Lance Creek-Old Woman Anticline District. Uranium concentrations in sediment samples range from 1.14 to 220.70 ppM and have a median of 3.37 ppM and a mean of 4.03 ppM. Throughout the major uranium mining districts of the Powder River Basin, sediment samples with high uranium concentrations were collected from dry streams located near wells producing water samples with high uranium concentrations. High uranium concentrations were also found associated with the Lance Creek oil field where uranium mineralization is known in the White River formation. High uranium concentrations were also found in sediment samples in areas where uranium mineralization is not known. These samples are from dry streams in areas underlain by the White River formation, the Niobrara formation, and the Pierre, Carlisle, Belle Fourche, and Mowry shales.

  9. 38 CFR 59.60 - Additional application requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... information requested for an application), 424C, and 424D (these forms are available on the internet Web site... documentation specified by VA Form 10-0388-5 (this form is available on the internet Web site provided in §...

  10. Benefits of additives application during combustion of phytomass

    NASA Astrophysics Data System (ADS)

    Palacka, Matej; Vician, Peter; Holubčík, Michal; Jandačka, Jozef

    2016-06-01

    Phytomass, particularly wheat straw as a source of energy has countless benefits, but it has many problems in its direct burn too. The worst problem is the ash flow temperature. The aim of study was to analyze and reduce the problems of the wheat straw combustion. The experiment was conducted under realistic conditions. In this paper was implemented analysis of ash features with and without adding additives into the wheat straw. Selected samples were laboratory processed and examined. The result of the work was the impact of additional additives for ash features.

  11. Application of Additively Manufactured Components in Rocket Engine Turbopumps

    NASA Technical Reports Server (NTRS)

    Calvert, Marty, Jr.; Hanks, Andrew; Schmauch, Preston; Delessio, Steve

    2015-01-01

    The use of additive manufacturing technology has the potential to revolutionize the development of turbopump components in liquid rocket engines. When designing turbomachinery with the additive process there are several benefits and risks that are leveraged relative to a traditional development cycle. This topic explores the details and development of a 90,000 RPM Liquid Hydrogen Turbopump from which 90% of the parts were derived from the additive process. This turbopump was designed, developed and will be tested later this year at Marshall Space Flight Center.

  12. 30 CFR 203.63 - Does my application have to include all leases in the field?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Royalty Relief for Pre-Act Deep Water Leases and for Development and Expansion Projects § 203.63 Does my... relief for a development project or an expansion project, your application does not have to include...

  13. 30 CFR 203.63 - Does my application have to include all leases in the field?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... in the field? 203.63 Section 203.63 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT... Sulfur General § 203.63 Does my application have to include all leases in the field? (a) For authorized... the date of application, except as provided in paragraph (a)(3) of this section and § 203.64....

  14. 45 CFR 2522.570 - What information on performance measures must my grant application include?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... APPLICANTS Evaluation Requirements Performance Measures: Requirements and Procedures § 2522.570 What information on performance measures must my grant application include? You must submit all of the following as... 45 Public Welfare 4 2010-10-01 2010-10-01 false What information on performance measures must...

  15. Simulation of Laser Additive Manufacturing and its Applications

    NASA Astrophysics Data System (ADS)

    Lee, Yousub

    Laser and metal powder based additive manufacturing (AM), a key category of advanced Direct Digital Manufacturing (DDM), produces metallic components directly from a digital representation of the part such as a CAD file. It is well suited for the production of high-value, customizable components with complex geometry and the repair of damaged components. Currently, the main challenges for laser and metal powder based AM include the formation of defects (e.g., porosity), low surface finish quality, and spatially non-uniform properties of material. Such challenges stem largely from the limited knowledge of complex physical processes in AM especially the molten pool physics such as melting, molten metal flow, heat conduction, vaporization of alloying elements, and solidification. Direct experimental measurement of melt pool phenomena is highly difficult since the process is localized (on the order of 0.1 mm to 1 mm melt pool size) and transient (on the order of 1 m/s scanning speed). Furthermore, current optical and infrared cameras are limited to observe the melt pool surface. As a result, fluid flows in the melt pool, melt pool shape and formation of sub-surface defects are difficult to be visualized by experiment. On the other hand, numerical simulation, based on rigorous solution of mass, momentum and energy transport equations, can provide important quantitative knowledge of complex transport phenomena taking place in AM. The overarching goal of this dissertation research is to develop an analytical foundation for fundamental understanding of heat transfer, molten metal flow and free surface evolution. Two key types of laser AM processes are studied: a) powder injection, commonly used for repairing of turbine blades, and b) powder bed, commonly used for manufacturing of new parts with complex geometry. In the powder injection simulation, fluid convection, temperature gradient (G), solidification rate (R) and melt pool shape are calculated using a heat transfer

  16. 49 CFR 260.25 - Additional information for Applicants not having a credit rating.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Additional information for Applicants not having a... Financial Assistance § 260.25 Additional information for Applicants not having a credit rating. Each application submitted by Applicants not having a recent credit rating from one or more nationally...

  17. Additional application of the NASCAP code. Volume 1: NASCAP extension

    NASA Technical Reports Server (NTRS)

    Katz, I.; Cassidy, J. J.; Mandell, M. J.; Parks, D. E.; Schnuelle, G. W.; Stannard, P. R.; Steen, P. G.

    1981-01-01

    The NASCAP computer program comprehensively analyzes problems of spacecraft charging. Using a fully three dimensional approach, it can accurately predict spacecraft potentials under a variety of conditions. Several changes were made to NASCAP, and a new code, NASCAP/LEO, was developed. In addition, detailed studies of several spacecraft-environmental interactions and of the SCATHA spacecraft were performed. The NASCAP/LEO program handles situations of relatively short Debye length encountered by large space structures or by any satellite in low earth orbit (LEO).

  18. Additive Manufacturing of Medical Models--Applications in Rhinology.

    PubMed

    Raos, Pero; Klapan, Ivica; Galeta, Tomislav

    2015-09-01

    In the paper we are introducing guidelines and suggestions for use of 3D image processing SW in head pathology diagnostic and procedures for obtaining physical medical model by additive manufacturing/rapid prototyping techniques, bearing in mind the improvement of surgery performance, its maximum security and faster postoperative recovery of patients. This approach has been verified in two case reports. In the treatment we used intelligent classifier-schemes for abnormal patterns using computer-based system for 3D-virtual and endoscopic assistance in rhinology, with appropriate visualization of anatomy and pathology within the nose, paranasal sinuses, and scull base area.

  19. 40 CFR 1039.725 - What must I include in my application for certification?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 33 2011-07-01 2011-07-01 false What must I include in my application... (positive or negative) based on projected production volumes. We may require you to include similar... positive emission credits you expect to use to offset the negative emission credits....

  20. 43 CFR 4300.21 - What must I include in my application?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...; REINDEER; GENERAL Applying for A Grazing Permit § 4300.21 What must I include in my application? (a) You must include a certification of reindeer allotment to you, signed by the Bureau of Indian Affairs, if you are to receive a herd from the Government. If you obtain reindeer from a source other than...

  1. 43 CFR 4300.21 - What must I include in my application?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...; REINDEER; GENERAL Applying for A Grazing Permit § 4300.21 What must I include in my application? (a) You must include a certification of reindeer allotment to you, signed by the Bureau of Indian Affairs, if you are to receive a herd from the Government. If you obtain reindeer from a source other than...

  2. 43 CFR 4300.21 - What must I include in my application?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...; REINDEER; GENERAL Applying for A Grazing Permit § 4300.21 What must I include in my application? (a) You must include a certification of reindeer allotment to you, signed by the Bureau of Indian Affairs, if you are to receive a herd from the Government. If you obtain reindeer from a source other than...

  3. 43 CFR 4300.21 - What must I include in my application?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...; REINDEER; GENERAL Applying for A Grazing Permit § 4300.21 What must I include in my application? (a) You must include a certification of reindeer allotment to you, signed by the Bureau of Indian Affairs, if you are to receive a herd from the Government. If you obtain reindeer from a source other than...

  4. 77 FR 57451 - Regulations Regarding the Application of Section 172(h) Including Consolidated Groups

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-17

    ... Regarding the Application of Section 172(h) Including Consolidated Groups; Proposed Rule #0;#0;Federal... Section 172(h) Including Consolidated Groups AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of proposed rulemaking. SUMMARY: This document contains proposed regulations under section...

  5. Diethyl fluoronitromethylphosphonate: synthesis and application in nucleophilic fluoroalkyl additions.

    PubMed

    Opekar, Stanislav; Pohl, Radek; Beran, Pavel; Rulíšek, Lubomír; Beier, Petr

    2014-01-27

    Diethyl fluoronitromethylphosphonate (3), a previously unknown compound, was synthesized by electrophilic fluorination of diethyl nitromethylphosphonate with Selectfluor. Base-induced decomposition of 3 was studied by NMR spectroscopy, which identified diethyl fluorophosphate and fluoronitromethane as the main decomposition products. C-H acidities [pK(a) values in dimethyl sulfoxide (DMSO)] of 3, 1-fluoro-1-phenylsulfonylmethanephosphonate (1; McCarthy's reagent), tetraethyl fluoromethylenebisphosphonate (2), and some nonfluorinated phosphonates were computed, and a good correlation between calculated and experimental pK(a) values was found. The calculated C-H acidities increased in the sequence 2<1<3. Diethyl fluoronitromethylphosphonate (3) was applied in the Horner-Wadsworth-Emmons reaction with aldehydes and trifluoromethyl ketones to provide new 1-fluoro-1-nitroalkenes with good to high stereoselectivities. Alkylation of 3 was successful only with iodomethane, however, conjugate additions of 3 to Michael acceptors such as α,β-unsaturated carbonyl compounds, sulfones, and nitro compounds allowed access to variously modified diethyl 1-fluoro-1-nitrophosphonates.

  6. 76 FR 55788 - Amendments To Include New Applicant Types on Form ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-09

    ... processing of the form. Form ID is the application for access codes to file on the Commission's Electronic..., 2011), 76 FR 10948 (February 28, 2011) (File No. S7-06-11). \\32\\ Id. \\33\\ See 15 U.S.C. 78c(a)(77) (as... COMMISSION 17 CFR Parts 239, 249, 269 and 274 Amendments To Include New Applicant Types on Form ID...

  7. Additive manufacturing of stretchable tactile sensors: Processes, materials, and applications

    NASA Astrophysics Data System (ADS)

    Vatani, Morteza

    3D printing technology is becoming more ubiquitous every day especially in the area of smart structures. However, fabrication of multi-material, functional, and smart structures is problematic because of the process and material limitations. This thesis sought to develop a Direct Print Photopolymerization (DPP) fabrication technique that appreciably extends the manufacturing space for the 3D smart structures. This method employs a robotically controlled micro-extrusion of a filament equipped with a photopolymerization process. The ability to use polymers and ultimately their nanocomposites in this process is the advantage of the proposed process over the current fabrication methods in the fabrication of 3D structures featuring mechanical, physical, and electrical functionalities. In addition, this study focused to develop a printable, conductive, and stretchable nanocomposite based on a photocurable and stretchable liquid resin filled with multi-walled carbon nanotubes (MWNTs). This nanocomposite exhibited piezoresistivity, means its resistivity changes as it deforms. This property is a favorable factor in developing resistance based tactile sensors. They were also able to resist high tensile strains while they showed conductivity. Furthermore, this study offered a possible and low-cost method to have a unique and highly stretchable pressure sensitive polymer. This disruptive pressure sensitive polymer composed of an Ionic Liquid (IL) and a stretchable photopolymer embedded between two layers of Carbon Nanotube (CNTs) based stretchable electrodes. The developed IL-polymer showed both field effect property and piezoresistivity that can detect large tensile strains up 30%. In summary, this research study focused to present feasible methods and materials for printing a 3D smart structure especially in the context of flexible tactile sensors. This study provides a foundation for the future efforts in fabrication of skin like tactile sensors in three-dimensional motifs

  8. 37 CFR 2.23 - Additional requirements for TEAS Plus application.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... TEAS Plus application. 2.23 Section 2.23 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND... § 2.23 Additional requirements for TEAS Plus application. (a) In addition to the filing requirements under § 2.22(a), the applicant must: (1) File the following communications through TEAS: (i)...

  9. 37 CFR 2.23 - Additional requirements for TEAS Plus application.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... TEAS Plus application. 2.23 Section 2.23 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND... § 2.23 Additional requirements for TEAS Plus application. (a) In addition to the filing requirements under § 2.22(a), the applicant must: (1) File the following communications through TEAS: (i)...

  10. 37 CFR 2.23 - Additional requirements for TEAS Plus application.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... TEAS Plus application. 2.23 Section 2.23 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND... § 2.23 Additional requirements for TEAS Plus application. (a) In addition to the filing requirements under § 2.22(a), the applicant must: (1) File the following communications through TEAS: (i)...

  11. 37 CFR 2.23 - Additional requirements for TEAS Plus application.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... TEAS Plus application. 2.23 Section 2.23 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND... § 2.23 Additional requirements for TEAS Plus application. (a) In addition to the filing requirements under § 2.22(a), the applicant must: (1) File the following communications through TEAS: (i)...

  12. 37 CFR 2.23 - Additional requirements for TEAS Plus application.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... TEAS Plus application. 2.23 Section 2.23 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND... § 2.23 Additional requirements for TEAS Plus application. (a) In addition to the filing requirements under § 2.22(a), the applicant must: (1) File the following communications through TEAS: (i)...

  13. Metrology test object for dimensional verification in additive manufacturing of metals for biomedical applications.

    PubMed

    Teeter, Matthew G; Kopacz, Alexander J; Nikolov, Hristo N; Holdsworth, David W

    2015-01-01

    Additive manufacturing continues to increase in popularity and is being used in applications such as biomaterial ingrowth that requires sub-millimeter dimensional accuracy. The purpose of this study was to design a metrology test object for determining the capabilities of additive manufacturing systems to produce common objects, with a focus on those relevant to medical applications. The test object was designed with a variety of features of varying dimensions, including holes, cylinders, rectangles, gaps, and lattices. The object was built using selective laser melting, and the produced dimensions were compared to the target dimensions. Location of the test objects on the build plate did not affect dimensions. Features with dimensions less than 0.300 mm did not build or were overbuilt to a minimum of 0.300 mm. The mean difference between target and measured dimensions was less than 0.100 mm in all cases. The test object is applicable to multiple systems and materials, tests the effect of location on the build, uses a minimum of material, and can be measured with a variety of efficient metrology tools (including measuring microscopes and micro-CT). Investigators can use this test object to determine the limits of systems and adjust build parameters to achieve maximum accuracy.

  14. Metrology test object for dimensional verification in additive manufacturing of metals for biomedical applications.

    PubMed

    Teeter, Matthew G; Kopacz, Alexander J; Nikolov, Hristo N; Holdsworth, David W

    2015-01-01

    Additive manufacturing continues to increase in popularity and is being used in applications such as biomaterial ingrowth that requires sub-millimeter dimensional accuracy. The purpose of this study was to design a metrology test object for determining the capabilities of additive manufacturing systems to produce common objects, with a focus on those relevant to medical applications. The test object was designed with a variety of features of varying dimensions, including holes, cylinders, rectangles, gaps, and lattices. The object was built using selective laser melting, and the produced dimensions were compared to the target dimensions. Location of the test objects on the build plate did not affect dimensions. Features with dimensions less than 0.300 mm did not build or were overbuilt to a minimum of 0.300 mm. The mean difference between target and measured dimensions was less than 0.100 mm in all cases. The test object is applicable to multiple systems and materials, tests the effect of location on the build, uses a minimum of material, and can be measured with a variety of efficient metrology tools (including measuring microscopes and micro-CT). Investigators can use this test object to determine the limits of systems and adjust build parameters to achieve maximum accuracy. PMID:25542613

  15. Evaluation of Select Surface Processing Techniques for In Situ Application During the Additive Manufacturing Build Process

    NASA Astrophysics Data System (ADS)

    Book, Todd A.; Sangid, Michael D.

    2016-07-01

    Although additive manufacturing offers numerous performance advantages for different applications, it is not being used for critical applications due to uncertainties in structural integrity as a result of innate process variability and defects. To minimize uncertainty, the current approach relies on the concurrent utilization of process monitoring, post-processing, and non-destructive inspection in addition to an extensive material qualification process. This paper examines an alternative approach by evaluating the application of select surface process techniques, to include sliding severe plastic deformation (SPD) and fine particle shot peening, on direct metal laser sintering-produced AlSi10Mg materials. Each surface processing technique is compared to baseline as-built and post-processed samples as a proof of concept for surface enhancement. Initial results pairing sliding SPD with the manufacture's recommended thermal stress relief cycle demonstrated uniform recrystallization of the microstructure, resulting in a more homogeneous distribution of strain among the microstructure than as-built or post-processed conditions. This result demonstrates the potential for the in situ application of various surface processing techniques during the layerwise direct metal laser sintering build process.

  16. 40 CFR 1037.725 - What must I include in my application for certification?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 34 2012-07-01 2012-07-01 false What must I include in my application for certification? 1037.725 Section 1037.725 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW HEAVY-DUTY MOTOR VEHICLES Averaging,...

  17. 40 CFR 1054.205 - What must I include in my application?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW, SMALL NONROAD SPARK-IGNITION ENGINES AND EQUIPMENT Certifying Emission Families § 1054.205 What must I include in my application? This section specifies the... 40 CFR part 1065. (h) Identify the emission family's useful life. Describe the basis for...

  18. 40 CFR 1054.205 - What must I include in my application?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW, SMALL NONROAD SPARK-IGNITION ENGINES AND EQUIPMENT Certifying Emission Families § 1054.205 What must I include in my application? This section specifies the... 40 CFR part 1065. (h) Identify the emission family's useful life. Describe the basis for...

  19. 40 CFR 1054.205 - What must I include in my application?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW, SMALL NONROAD SPARK-IGNITION ENGINES AND EQUIPMENT Certifying Emission Families § 1054.205 What must I include in my application? This section specifies the... ranges we specify in 40 CFR part 1065. (h) Identify the emission family's useful life. Describe the...

  20. 40 CFR 1054.205 - What must I include in my application?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW, SMALL NONROAD SPARK-IGNITION ENGINES AND EQUIPMENT Certifying Emission Families § 1054.205 What must I include in my application? This section specifies the... 40 CFR part 1065. (h) Identify the emission family's useful life. Describe the basis for...

  1. 40 CFR 1051.205 - What must I include in my application?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... test data only for one grade unless the regulations of this part specify otherwise for your engine. (2... 40 Protection of Environment 34 2012-07-01 2012-07-01 false What must I include in my application? 1051.205 Section 1051.205 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED)...

  2. 40 CFR 1051.205 - What must I include in my application?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... test data only for one grade unless the regulations of this part specify otherwise for your engine. (2... 40 Protection of Environment 33 2011-07-01 2011-07-01 false What must I include in my application? 1051.205 Section 1051.205 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED)...

  3. 40 CFR 1060.205 - What must I include in my application?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... this part applicable only to handheld Small SI equipment, state that the requested certificate would apply only for handheld Small SI equipment. (f) Identify the emission family's useful life. (g) Include... the emission family comply with the requirements of this part, other referenced parts of the CFR,...

  4. 34 CFR 350.66 - What must a grantee include in a patent application?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true What must a grantee include in a patent application? 350.66 Section 350.66 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION DISABILITY...

  5. 34 CFR 350.66 - What must a grantee include in a patent application?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false What must a grantee include in a patent application? 350.66 Section 350.66 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION DISABILITY...

  6. 34 CFR 350.66 - What must a grantee include in a patent application?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true What must a grantee include in a patent application? 350.66 Section 350.66 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION DISABILITY...

  7. 34 CFR 350.66 - What must a grantee include in a patent application?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false What must a grantee include in a patent application? 350.66 Section 350.66 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION DISABILITY...

  8. 34 CFR 350.66 - What must a grantee include in a patent application?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false What must a grantee include in a patent application? 350.66 Section 350.66 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION DISABILITY...

  9. 40 CFR 1054.725 - What must I include in my application for certification?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 33 2011-07-01 2011-07-01 false What must I include in my application... calculated at the end of the year. (2) Detailed calculations of projected emission credits (positive or... the model year. If you project negative emission credits for a family, state the source of...

  10. 40 CFR 1051.725 - What must I include in my applications for certification?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 33 2011-07-01 2011-07-01 false What must I include in my applications... traded credits) to offset the deficit. (2) Detailed calculations of projected emission credits (positive... source of positive emission credits you expect to use to offset the negative emission credits....

  11. 40 CFR 1045.725 - What must I include in my application for certification?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 33 2011-07-01 2011-07-01 false What must I include in my application... calculated at the end of the year. (2) Detailed calculations of projected emission credits (positive or... the model year. If you project negative emission credits for a family, state the source of...

  12. 13 CFR 134.611 - What should I include in my application for an award?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... RULES OF PROCEDURE GOVERNING CASES BEFORE THE OFFICE OF HEARINGS AND APPEALS Implementation of the Equal Access to Justice Act § 134.611 What should I include in my application for an award? (a) Your.... It must contain the following information: (1) A statement that OHA has jurisdiction over the...

  13. 30 CFR 580.12 - What must I include in my application or notification?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... notification? 580.12 Section 580.12 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE... nonrefundable service fee of $2,012 must be paid electronically through Pay.gov at: https://www.pay.gov/paygov/ and you must include a copy of the Pay.gov confirmation receipt page with your application....

  14. 30 CFR 580.12 - What must I include in my application or notification?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... notification? 580.12 Section 580.12 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE... nonrefundable service fee of $2,012 must be paid electronically through Pay.gov at: https://www.pay.gov/paygov/ and you must include a copy of the Pay.gov confirmation receipt page with your application....

  15. 30 CFR 580.12 - What must I include in my application or notification?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... notification? 580.12 Section 580.12 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE... nonrefundable service fee of $2,012 must be paid electronically through Pay.gov at: https://www.pay.gov/paygov/ and you must include a copy of the Pay.gov confirmation receipt page with your application....

  16. 34 CFR 367.11 - What assurances must a DSA include in its application?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) and (b), and consistent with 34 CFR 364.28, the DSA will seek to incorporate into and describe in the... section 704 of the Act and subpart C of 34 CFR part 364; and (g) The applicant has been designated by the... 34 Education 2 2014-07-01 2013-07-01 true What assurances must a DSA include in its...

  17. 34 CFR 367.11 - What assurances must a DSA include in its application?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false What assurances must a DSA include in its application? 367.11 Section 367.11 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION INDEPENDENT LIVING SERVICES FOR OLDER INDIVIDUALS WHO ARE...

  18. 34 CFR 367.11 - What assurances must a DSA include in its application?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) and (b), and consistent with 34 CFR 364.28, the DSA will seek to incorporate into and describe in the... section 704 of the Act and subpart C of 34 CFR part 364; and (g) The applicant has been designated by the... 34 Education 2 2013-07-01 2013-07-01 false What assurances must a DSA include in its...

  19. 29 CFR 575.4 - Information to be included in application.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Information to be included in application. 575.4 Section 575.4 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS WAIVER OF CHILD LABOR PROVISIONS FOR AGRICULTURAL EMPLOYMENT OF 10 AND 11 YEAR OLD MINORS IN...

  20. 29 CFR 575.4 - Information to be included in application.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Information to be included in application. 575.4 Section 575.4 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS WAIVER OF CHILD LABOR PROVISIONS FOR AGRICULTURAL EMPLOYMENT OF 10 AND 11 YEAR OLD MINORS IN...

  1. 29 CFR 575.4 - Information to be included in application.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Information to be included in application. 575.4 Section 575.4 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS WAIVER OF CHILD LABOR PROVISIONS FOR AGRICULTURAL EMPLOYMENT OF 10 AND 11 YEAR OLD MINORS IN...

  2. 29 CFR 575.4 - Information to be included in application.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Information to be included in application. 575.4 Section 575.4 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS WAIVER OF CHILD LABOR PROVISIONS FOR AGRICULTURAL EMPLOYMENT OF 10 AND 11 YEAR OLD MINORS IN...

  3. 29 CFR 575.4 - Information to be included in application.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Information to be included in application. 575.4 Section 575.4 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS WAIVER OF CHILD LABOR PROVISIONS FOR AGRICULTURAL EMPLOYMENT OF 10 AND 11 YEAR OLD MINORS IN...

  4. 34 CFR 367.11 - What assurances must a DSA include in its application?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) and (b), and consistent with 34 CFR 364.28, the DSA will seek to incorporate into and describe in the... section 704 of the Act and subpart C of 34 CFR part 364; and (g) The applicant has been designated by the... 34 Education 2 2010-07-01 2010-07-01 false What assurances must a DSA include in its...

  5. 40 CFR 1045.205 - What must I include in my application?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... engines, if applicable. (b) Explain how the emission control systems operate. Describe in detail all system components for controlling exhaust emissions, including all auxiliary emission control devices... specified in 40 CFR part 1068, Appendix III. For example, engine owners should have ready access...

  6. 40 CFR 1051.205 - What must I include in my application?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... we specify in 40 CFR part 1065. (h) Identify the engine family's useful life. (i) Include the... application in certain cases without new emission data. (p) Report test results as follows: (1) Report all... your tests were valid under the requirements of this part and 40 CFR parts 86 and 1065. (2)...

  7. 34 CFR 606.12 - What must be included in cooperative arrangement grant applications?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false What must be included in cooperative arrangement grant applications? 606.12 Section 606.12 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION DEVELOPING...

  8. 34 CFR 606.12 - What must be included in cooperative arrangement grant applications?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What must be included in cooperative arrangement grant applications? 606.12 Section 606.12 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION DEVELOPING...

  9. 34 CFR 606.12 - What must be included in cooperative arrangement grant applications?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false What must be included in cooperative arrangement grant applications? 606.12 Section 606.12 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION DEVELOPING...

  10. 34 CFR 606.12 - What must be included in cooperative arrangement grant applications?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false What must be included in cooperative arrangement grant applications? 606.12 Section 606.12 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION DEVELOPING...

  11. 34 CFR 606.12 - What must be included in cooperative arrangement grant applications?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false What must be included in cooperative arrangement grant applications? 606.12 Section 606.12 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION DEVELOPING...

  12. 30 CFR 280.12 - What must I include in my application or notification?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I include in my application or notification? 280.12 Section 280.12 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE PROSPECTING FOR MINERALS OTHER THAN OIL, GAS, AND SULPHUR ON THE OUTER CONTINENTAL SHELF How...

  13. 30 CFR 280.12 - What must I include in my application or notification?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What must I include in my application or notification? 280.12 Section 280.12 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE PROSPECTING FOR MINERALS OTHER THAN OIL, GAS, AND SULPHUR...

  14. 40 CFR 1036.205 - What must I include in my application?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... described in 40 CFR 86.007-21, with the following additional information: (a) Describe the engine family's... test procedures you used (see 40 CFR 1065.10(c)). (c) Include the emission-related installation... referenced parts of the CFR, and the Clean Air Act. Note that § 1036.235 specifies which engines to test...

  15. 41 CFR 302-7.21 - If my HHG shipment includes an item for which a weight additive is assessed by the HHG carrier (e...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 4 2014-07-01 2014-07-01 false If my HHG shipment includes an item for which a weight additive is assessed by the HHG carrier (e.g., boat, trailer... is assessed by the HHG carrier (e.g., boat, trailer, ultralight vehicle), am I responsible...

  16. 41 CFR 302-7.21 - If my HHG shipment includes an item for which a weight additive is assessed by the HHG carrier (e...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 41 Public Contracts and Property Management 4 2012-07-01 2012-07-01 false If my HHG shipment includes an item for which a weight additive is assessed by the HHG carrier (e.g., boat, trailer... Management Federal Travel Regulation System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY...

  17. 41 CFR 302-7.21 - If my HHG shipment includes an item for which a weight additive is assessed by the HHG carrier (e...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 4 2013-07-01 2012-07-01 true If my HHG shipment includes an item for which a weight additive is assessed by the HHG carrier (e.g., boat, trailer... Management Federal Travel Regulation System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY...

  18. 21 CFR 174.5 - General provisions applicable to indirect food additives.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... additives. 174.5 Section 174.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) INDIRECT FOOD ADDITIVES: GENERAL § 174.5 General provisions applicable to indirect food additives. (a) Regulations prescribing conditions under which food additive substances may...

  19. 28 CFR 34.4 - Additional competitive application requirements and procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... AND PEER REVIEW PROCEDURES Competition § 34.4 Additional competitive application requirements and... particular part C program area covered by the announced program (peer review). Supplementary application review procedures, in addition to internal review and peer review, may be used for each competitive...

  20. 28 CFR 34.4 - Additional competitive application requirements and procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... AND PEER REVIEW PROCEDURES Competition § 34.4 Additional competitive application requirements and... particular part C program area covered by the announced program (peer review). Supplementary application review procedures, in addition to internal review and peer review, may be used for each competitive...

  1. 28 CFR 34.4 - Additional competitive application requirements and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... AND PEER REVIEW PROCEDURES Competition § 34.4 Additional competitive application requirements and... particular part C program area covered by the announced program (peer review). Supplementary application review procedures, in addition to internal review and peer review, may be used for each competitive...

  2. 28 CFR 34.4 - Additional competitive application requirements and procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... AND PEER REVIEW PROCEDURES Competition § 34.4 Additional competitive application requirements and... particular part C program area covered by the announced program (peer review). Supplementary application review procedures, in addition to internal review and peer review, may be used for each competitive...

  3. 24 CFR 570.711 - State borrowers; additional requirements and application procedures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... DEVELOPMENT BLOCK GRANTS Loan Guarantees § 570.711 State borrowers; additional requirements and application... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false State borrowers; additional requirements and application procedures. 570.711 Section 570.711 Housing and Urban Development...

  4. 18 CFR 33.4 - Additional information requirements for applications involving vertical competitive impacts.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Additional information requirements for applications involving vertical competitive impacts. 33.4 Section 33.4 Conservation of Power... FEDERAL POWER ACT APPLICATIONS UNDER FEDERAL POWER ACT SECTION 203 § 33.4 Additional...

  5. 18 CFR 33.4 - Additional information requirements for applications involving vertical competitive impacts.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Additional information requirements for applications involving vertical competitive impacts. 33.4 Section 33.4 Conservation of Power... FEDERAL POWER ACT APPLICATIONS UNDER FEDERAL POWER ACT SECTION 203 § 33.4 Additional...

  6. 29 CFR 1926.452 - Additional requirements applicable to specific types of scaffolds.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... scaffolds. 1926.452 Section 1926.452 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND... Scaffolds § 1926.452 Additional requirements applicable to specific types of scaffolds. In addition to the applicable requirements of § 1926.451, the following requirements apply to the specific types of...

  7. 29 CFR 1926.452 - Additional requirements applicable to specific types of scaffolds.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... scaffolds. 1926.452 Section 1926.452 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND... Scaffolds § 1926.452 Additional requirements applicable to specific types of scaffolds. In addition to the applicable requirements of § 1926.451, the following requirements apply to the specific types of...

  8. 29 CFR 1926.452 - Additional requirements applicable to specific types of scaffolds.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... scaffolds. 1926.452 Section 1926.452 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND... Scaffolds § 1926.452 Additional requirements applicable to specific types of scaffolds. In addition to the applicable requirements of § 1926.451, the following requirements apply to the specific types of...

  9. 29 CFR 1926.452 - Additional requirements applicable to specific types of scaffolds.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... scaffolds. 1926.452 Section 1926.452 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND... Scaffolds § 1926.452 Additional requirements applicable to specific types of scaffolds. In addition to the applicable requirements of § 1926.451, the following requirements apply to the specific types of...

  10. 29 CFR 1926.452 - Additional requirements applicable to specific types of scaffolds.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... scaffolds. 1926.452 Section 1926.452 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND... Scaffolds § 1926.452 Additional requirements applicable to specific types of scaffolds. In addition to the applicable requirements of § 1926.451, the following requirements apply to the specific types of...

  11. Tardigrada of Ireland: a review of records and an updated checklist of species including a new addition to the Irish fauna.

    PubMed

    DeMilio, Erica; Lawton, Colin; Marley, Nigel J

    2016-01-01

    The phylum Tardigrada was not recorded in Ireland until the Clare Island Survey of 1909-1911, with only rare subsequent reports on Irish tardigrade species. In recent decades, significant taxonomic revision has occurred within Tardigrada. This has resulted in the need for a review of all known historical records from Ireland and Northern Ireland in order to produce an updated checklist of valid taxa. The new checklist includes fifty-one tardigrade species and subspecies including a new addition to the Irish fauna reported herein, Echiniscus quadrispinosus quadrispinosus Richters, 1902 from Newtown, Ballyvaughan, Co. Clare. PMID:27667947

  12. Tardigrada of Ireland: a review of records and an updated checklist of species including a new addition to the Irish fauna.

    PubMed

    DeMilio, Erica; Lawton, Colin; Marley, Nigel J

    2016-01-01

    The phylum Tardigrada was not recorded in Ireland until the Clare Island Survey of 1909-1911, with only rare subsequent reports on Irish tardigrade species. In recent decades, significant taxonomic revision has occurred within Tardigrada. This has resulted in the need for a review of all known historical records from Ireland and Northern Ireland in order to produce an updated checklist of valid taxa. The new checklist includes fifty-one tardigrade species and subspecies including a new addition to the Irish fauna reported herein, Echiniscus quadrispinosus quadrispinosus Richters, 1902 from Newtown, Ballyvaughan, Co. Clare.

  13. Tardigrada of Ireland: a review of records and an updated checklist of species including a new addition to the Irish fauna

    PubMed Central

    DeMilio, Erica; Lawton, Colin; Marley, Nigel J.

    2016-01-01

    Abstract The phylum Tardigrada was not recorded in Ireland until the Clare Island Survey of 1909–1911, with only rare subsequent reports on Irish tardigrade species. In recent decades, significant taxonomic revision has occurred within Tardigrada. This has resulted in the need for a review of all known historical records from Ireland and Northern Ireland in order to produce an updated checklist of valid taxa. The new checklist includes fifty-one tardigrade species and subspecies including a new addition to the Irish fauna reported herein, Echiniscus quadrispinosus quadrispinosus Richters, 1902 from Newtown, Ballyvaughan, Co. Clare. PMID:27667947

  14. Tardigrada of Ireland: a review of records and an updated checklist of species including a new addition to the Irish fauna

    PubMed Central

    DeMilio, Erica; Lawton, Colin; Marley, Nigel J.

    2016-01-01

    Abstract The phylum Tardigrada was not recorded in Ireland until the Clare Island Survey of 1909–1911, with only rare subsequent reports on Irish tardigrade species. In recent decades, significant taxonomic revision has occurred within Tardigrada. This has resulted in the need for a review of all known historical records from Ireland and Northern Ireland in order to produce an updated checklist of valid taxa. The new checklist includes fifty-one tardigrade species and subspecies including a new addition to the Irish fauna reported herein, Echiniscus quadrispinosus quadrispinosus Richters, 1902 from Newtown, Ballyvaughan, Co. Clare.

  15. 21 CFR 174.5 - General provisions applicable to indirect food additives.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... additives. 174.5 Section 174.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) INDIRECT FOOD ADDITIVES: GENERAL § 174.5 General provisions applicable to indirect food additives. (a) Regulations prescribing conditions...

  16. 21 CFR 174.5 - General provisions applicable to indirect food additives.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... additives. 174.5 Section 174.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) INDIRECT FOOD ADDITIVES: GENERAL § 174.5 General provisions applicable to indirect food additives. (a) Regulations prescribing conditions...

  17. 21 CFR 174.5 - General provisions applicable to indirect food additives.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... additives. 174.5 Section 174.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) INDIRECT FOOD ADDITIVES: GENERAL § 174.5 General provisions applicable to indirect food additives. (a) Regulations prescribing conditions...

  18. 21 CFR 174.5 - General provisions applicable to indirect food additives.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... additives. 174.5 Section 174.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) INDIRECT FOOD ADDITIVES: GENERAL § 174.5 General provisions applicable to indirect food additives. (a) Regulations prescribing conditions...

  19. Microwave Technology for Waste Management Applications Including Disposition of Electronic Circuitry

    SciTech Connect

    Wicks, G.G.; Clark, D.E.; Schulz, R.L.

    1998-06-01

    Advanced microwave technology is being developed nationally and internationally for a variety of waste management and environmental remediation purposes. These efforts include treatment and destruction of a vast array of gaseous, liquid and solid hazardous wastes as well as subsequent immobilization of hazardous components into leach resistant forms. Microwave technology provides an important contribution to an arsenal of existing remediation methods that are designed to protect the public and environment from the undesirable consequences of hazardous materials. One application of special interest is the treatment of discarded electronic circuitry using a new hybrid microwave treatment process and subsequent reclamation of the precious metals within.

  20. Microwave technology for waste management applications including disposition of electronic circuitry

    SciTech Connect

    Wicks, G.G.; Clark, D.E.; Schulz, R.L.; Folz, D.C.

    1995-09-01

    Microwave technology is being developed nationally and internationally for a variety of environmental remediation purposes. These efforts include treatment and destruction of a vast array of gaseous, liquid and solid hazardous wastes as well as subsequent immobilization of selected components. Microwave technology provides an important contribution to an arsenal of existing remediation methods that are designed to protect the public and environment from undesirable consequences of hazardous materials. Applications of microwave energy for environmental remediation will be discussed. Emphasized will be a newly developed microwave process designed to treat discarded electronic circuitry and reclaim the precious metals within for reuse.

  1. Application of laser ultrasonic non-destructive evaluation technique to additive manufacturing

    NASA Astrophysics Data System (ADS)

    Manzo, Anthony J.; Kenderian, Shant; Helvajian, Henry

    2016-04-01

    The change in properties of a propagating ultrasonic wave has been a mainstay characterization tool of the nondestructive evaluation (NDE) industry for identifying subsurface defects (e.g. damage). A variant of this concept could be applicable to 3D additive manufacturing where the existence of defects (e.g. pores) within a sub-layer could mark a product as non-qualifying. We have been exploring the utility of pulsed laser ultrasonic excitation coupled with CW laser heterodyne detection as an all optical scheme for characterizing sub surface layer properties. The all-optical approach permits a straight forward integration into a laser additive processing tool. To test the concept, we have developed an experimental system that generates pulsed ultrasonic waves (the probe) with high bandwidth (<<10MHz) and a surface displacement sensor that can capture the ultrasonic "return" signal with bandwidth close to 300 MHz. The use of high frequencies enables the detection of smaller defect sites. The technique is time resolved with the sensor and probe as point (>>30-200 microns) beams. Current tests include characterizing properties of spot weld joints between two thin stainless steel plates. The long term objective is to transition the technique into a laser additive manufacturing tool.

  2. 75 FR 60721 - Aerospace Supplier Development Mission to China; Recruitment Reopened for Additional Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE International Trade Administration Aerospace Supplier Development Mission to China; Recruitment Reopened for Additional Applications AGENCY: International Trade Administration, Department of Commerce. ACTION:...

  3. 75 FR 9114 - Defense Federal Acquisition Regulation Supplement; Additional Requirements Applicable to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-01

    ... Defense Acquisition Regulations System 48 CFR Part 217 Defense Federal Acquisition Regulation Supplement; Additional Requirements Applicable to Multiyear Contracts (DFARS Case 2008-D023) AGENCY: Defense Acquisition... is issuing this interim rule amending the Defense Federal Acquisition Regulation Supplement...

  4. The influence of sterilization on nitrogen-included ultrananocrystalline diamond for biomedical applications.

    PubMed

    Tong, Wei; Tran, Phong A; Turnley, Ann M; Aramesh, Morteza; Prawer, Steven; Brandt, Milan; Fox, Kate

    2016-04-01

    Diamond has shown great potential in different biomedical applications, but the effects of sterilization on its properties have not been investigated. Here, we studied the influence of five sterilization techniques (solvent cleaning, oxygen plasma, UV irradiation, autoclave and hydrogen peroxide) on nitrogen-included ultrananocrystalline diamond. The chemical modification of the diamond surface was evaluated using X-ray photoelectron spectroscopy and water contact angle measurements. Different degrees of surface oxidation and selective sp(2) bonded carbon etching were found following all sterilization techniques, resulting in an increase of hydrophilicity. Higher viabilities of in vitro mouse 3T3 fibroblasts and rat cortical neuron cells were observed on oxygen plasma, autoclave and hydrogen peroxide sterilized diamond, which correlated with their higher hydrophilicity. By examination of apatite formation in simulated body fluid, in vivo bioactivity was predicted to be best on those surfaces which have been oxygen plasma treated and lowest on those which have been exposed to UV irradiation. The charge injection properties were also altered by the sterilization process and there appears to be a correlation between these changes and the degree of oxygen termination of the surface. We find that the modification brought by autoclave, oxygen plasma and hydrogen peroxide were most consistent with the use of N-UNCD in biological applications as compared to samples sterilized by solvent cleaning or UV exposure or indeed non-sterilized. A two-step process of sterilization by hydrogen peroxide following oxygen plasma treatment was then suggested. However, the final choice of sterilization technique will depend on the intended end application.

  5. 40 CFR 1048.225 - How do I amend my application for certification to include new or modified engine configurations?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... part. (c) We may ask for more test data or engineering evaluations. You must give us these within 30... application if any changes occur with respect to any information included in your application. (a) You must... components you described in your application for certification. This includes production and design...

  6. 10 CFR 431.175 - Additional requirements applicable to non-Voluntary Independent Certification Program participants.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Additional requirements applicable to non-Voluntary Independent Certification Program participants. 431.175 Section 431.175 Energy DEPARTMENT OF ENERGY ENERGY... requirements applicable to non-Voluntary Independent Certification Program participants. If you are...

  7. 10 CFR 52.158 - Contents of application; additional technical information.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    .... 52.158 Section 52.158 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Manufacturing Licenses § 52.158 Contents of application; additional... environmental report as required by 10 CFR 51.54. (2) If the manufacturing license application references...

  8. 10 CFR 52.158 - Contents of application; additional technical information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... 52.158 Section 52.158 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Manufacturing Licenses § 52.158 Contents of application; additional... environmental report as required by 10 CFR 51.54. (2) If the manufacturing license application references...

  9. 10 CFR 52.158 - Contents of application; additional technical information.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .... 52.158 Section 52.158 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Manufacturing Licenses § 52.158 Contents of application; additional... environmental report as required by 10 CFR 51.54. (2) If the manufacturing license application references...

  10. 10 CFR 52.158 - Contents of application; additional technical information.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... 52.158 Section 52.158 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Manufacturing Licenses § 52.158 Contents of application; additional... environmental report as required by 10 CFR 51.54. (2) If the manufacturing license application references...

  11. 24 CFR 570.466 - Additional application submission requirements for Pockets of Poverty-employment opportunities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... FACILITIES COMMUNITY DEVELOPMENT BLOCK GRANTS Urban Development Action Grants § 570.466 Additional application submission requirements for Pockets of Poverty—employment opportunities. Applicants for Action... types of new jobs (construction and permanent) that will be provided to the low- and...

  12. Including shielding effects in application of the TPCA method for detection of embedded radiation sources.

    SciTech Connect

    Johnson, William C.; Shokair, Isaac R.

    2011-12-01

    Conventional full spectrum gamma spectroscopic analysis has the objective of quantitative identification of all the radionuclides present in a measurement. For low-energy resolution detectors such as NaI, when photopeaks alone are not sufficient for complete isotopic identification, such analysis requires template spectra for all the radionuclides present in the measurement. When many radionuclides are present it is difficult to make the correct identification and this process often requires many attempts to obtain a statistically valid solution by highly skilled spectroscopists. A previous report investigated using the targeted principal component analysis method (TPCA) for detection of embedded sources for RPM applications. This method uses spatial/temporal information from multiple spectral measurements to test the hypothesis of the presence of a target spectrum of interest in these measurements without the need to identify all the other radionuclides present. The previous analysis showed that the TPCA method has significant potential for automated detection of target radionuclides of interest, but did not include the effects of shielding. This report complements the previous analysis by including the effects of spectral distortion due to shielding effects for the same problem of detection of embedded sources. Two examples, one with one target radionuclide and the other with two, show that the TPCA method can successfully detect shielded targets in the presence of many other radionuclides. The shielding parameters are determined as part of the optimization process using interpolation of library spectra that are defined on a 2D grid of atomic numbers and areal densities.

  13. System-Cost-Optimized Smart EVSE for Residential Application: Final Technical Report including Manufacturing Plan

    SciTech Connect

    Zhu, Charles

    2015-05-15

    In the 2nd quarter of 2012, a program was formally initiated at Delta Products to develop smart-grid-enabled Electric Vehicle Supply Equipment (EVSE) product for residential use. The project was funded in part by the U.S. Department of Energy (DOE), under award DE-OE0000590. Delta products was the prime contractor to DOE during the three year duration of the project. In addition to Delta Products, several additional supplier-partners were engaged in this research and development (R&D) program, including Detroit Edison DTE, Mercedes Benz Research and Development North America, and kVA. This report summarizes the program and describes the key research outcomes of the program. A technical history of the project activities is provided, which describes the key steps taken in the research and the findings made at successive stages in the multi-stage work. The evolution of an EVSE prototype system is described in detail, culminating in prototypes shipped to Department of Energy Laboratories for final qualification. After the program history is reviewed, the key attributes of the resulting EVSE are described in terms of functionality, performance, and cost. The results clearly demonstrate the ability of this EVSE to meet or exceed DOE's targets for this program, including: construction of a working product-intent prototype of a smart-grid-enabled EVSE, with suitable connectivity to grid management and home-energy management systems, revenue-grade metering, and related technical functions; and cost reduction of 50% or more compared to typical market priced EVSEs at the time of DOE's funding opportunity announcement (FOA), which was released in mid 2011. In addition to meeting all the program goals, the program was completed within the original budget and timeline established at the time of the award. The summary program budget and timeline, comparing plan versus actual values, is provided for reference, along with several supporting explanatory notes. Technical information

  14. Cerebriform variant type of T cell prolymphocytic leukemia with complex karyotype including an additional segment at 1p36.1.

    PubMed

    Kasahara, Senji; Tsurumi, Hisashi; Shibata, Yuhei; Matsumoto, Takuro; Nakamura, Nobuhiko; Nakamura, Hiroshi; Kanemura, Nobuhiro; Goto, Naoe; Hara, Takeshi; Moriwaki, Hisataka

    2012-11-01

    We describe two patients with T cell prolymphocytic leukemia (T-PLL) who exhibited the same complex karyotype, including an additional segment at 1p36.1. One presented with secondary progression following an initial stable clinical course, and the other with typically progressive disease. Features of the cerebriform variant were identified in the peripheral blood of both patients. Aggressive symptoms, such as lymphocytosis, lymphadenopathy, pleural effusion, cutaneous involvement and hepatosplenomegaly, developed during the progressive phases. Levels of serum soluble interleukin 2 receptor increased when symptoms worsened. These patients did not have the karyotypic 14q11 abnormality and trisomy 8q that are features of non-Japanese patients. The prognoses of these patients were poor; one survived for 2 months and the other survived for 10 months after progression. A chromosomal abnormality may occur in other types of aggressive T-PLL, particularly when extramedullary infiltration is a feature.

  15. [FADCC in NIHS for prior consultation system of application of food additives].

    PubMed

    Akiyama, Hiroshi; Sato, Kyoko

    2015-01-01

    An increasing number of inquiries about application of food additives have been made from businesses in and outside Japan. The Ministry of Health, Labour and Welfare (MHLW) is requested to expedite the procedure for designation and revision of use standards. In June 2014, the MHLW set up a center for consultation on application concerning food additives (Food Additive Designation Consultation Center, FADCC) in the National Institute of Health Sciences, aiming to smoothly and expeditiously handle clerical work for designation or revision of the use standards. FADCC gives advice on how to prepare documents on the information such as physicochemical characteristics, effectiveness, safety, daily intake and use standards, based on actual cases and experience.

  16. Application of a New Method for Analyzing Images: Two-Dimensional Non-Linear Additive Decomposition

    SciTech Connect

    MA Zaccaria; DM Drudnoy; JE Stasenko

    2006-07-05

    This paper documents the application of a new image processing algorithm, two-dimensional non-linear additive decomposition (NLAD), which is used to identify regions in a digital image whose gray-scale (or color) intensity is different than the surrounding background. Standard image segmentation algorithms exist that allow users to segment images based on gray-scale intensity and/or shape. However, these processing techniques do not adequately account for the image noise and lighting variation that typically occurs across an image. NLAD is designed to separate image noise and background from artifacts thereby providing the ability to consistently evaluate images. The decomposition techniques used in this algorithm are based on the concepts of mathematical morphology. NLAD emulates the human capability of visually separating an image into different levels of resolution components, denoted as ''coarse'', ''fine'', and ''intermediate''. Very little resolution information overlaps any two of the component images. This method can easily determine and/or remove trends and noise from an image. NLAD has several additional advantages over conventional image processing algorithms, including no need for a transformation from one space to another, such as is done with Fourier transforms, and since only finite summations are required, the calculational effort is neither extensive nor complicated.

  17. Comparison between computations and experimental data in unsteady three-dimensional transonic aerodynamics, including aeroelastic applications

    NASA Technical Reports Server (NTRS)

    Guruswamy, P.; Goorjian, P. M.

    1982-01-01

    Comparisons were made of computed and experimental data in three-dimensional unsteady transonic aerodynamics, including aeroelastic applications. The computer code LTRAN3, which is based on small-disturbance aerodynamic theory, was used to obtain the aerodynamic data. A procedure based on the U-g method was developed to compute flutter boundaries by using the unsteady aerodynamic coefficients obtained from LTRAN3. The experimental data were obtained from available NASA publications. All the studies were conducted for thin, unswept, rectangular wings with circular-arc cross sections. Numerical and experimental steady and unsteady aerodynamic data were compared for a wing with an aspect ratio of 3 and a thickness ratio of 5% at Mach numbers of 0.7 and 0.9. Flutter data were compared for a wing with an aspect ratio of 5. Two thickness ratios, 6% at Mach numbers of 0.715, 0.851, and 0.913, and 4% at Mach number of 0.904, were considered. Based on the unsteady aerodynamic data obtained from LTRAN3, flutter boundaries were computed; they were compared with those obtained from experiments and the code NASTRAN, which uses linear aerodynamics.

  18. Impacts of nitrogen addition on plant biodiversity in mountain grasslands depend on dose, application duration and climate: a systematic review.

    PubMed

    Humbert, Jean-Yves; Dwyer, John M; Andrey, Aline; Arlettaz, Raphaël

    2016-01-01

    Although the influence of nitrogen (N) addition on grassland plant communities has been widely studied, it is still unclear whether observed patterns and underlying mechanisms are constant across biomes. In this systematic review, we use meta-analysis and metaregression to investigate the influence of N addition (here referring mostly to fertilization) upon the biodiversity of temperate mountain grasslands (including montane, subalpine and alpine zones). Forty-two studies met our criteria of inclusion, resulting in 134 measures of effect size. The main general responses of mountain grasslands to N addition were increases in phytomass and reductions in plant species richness, as observed in lowland grasslands. More specifically, the analysis reveals that negative effects on species richness were exacerbated by dose (ha(-1) year(-1) ) and duration of N application (years) in an additive manner. Thus, sustained application of low to moderate levels of N over time had effects similar to short-term application of high N doses. The climatic context also played an important role: the overall effects of N addition on plant species richness and diversity (Shannon index) were less pronounced in mountain grasslands experiencing cool rather than warm summers. Furthermore, the relative negative effect of N addition on species richness was more pronounced in managed communities and was strongly negatively related to N-induced increases in phytomass, that is the greater the phytomass response to N addition, the greater the decline in richness. Altogether, this review not only establishes that plant biodiversity of mountain grasslands is negatively affected by N addition, but also demonstrates that several local management and abiotic factors interact with N addition to drive plant community changes. This synthesis yields essential information for a more sustainable management of mountain grasslands, emphasizing the importance of preserving and restoring grasslands with both low

  19. Impacts of nitrogen addition on plant biodiversity in mountain grasslands depend on dose, application duration and climate: a systematic review.

    PubMed

    Humbert, Jean-Yves; Dwyer, John M; Andrey, Aline; Arlettaz, Raphaël

    2016-01-01

    Although the influence of nitrogen (N) addition on grassland plant communities has been widely studied, it is still unclear whether observed patterns and underlying mechanisms are constant across biomes. In this systematic review, we use meta-analysis and metaregression to investigate the influence of N addition (here referring mostly to fertilization) upon the biodiversity of temperate mountain grasslands (including montane, subalpine and alpine zones). Forty-two studies met our criteria of inclusion, resulting in 134 measures of effect size. The main general responses of mountain grasslands to N addition were increases in phytomass and reductions in plant species richness, as observed in lowland grasslands. More specifically, the analysis reveals that negative effects on species richness were exacerbated by dose (ha(-1) year(-1) ) and duration of N application (years) in an additive manner. Thus, sustained application of low to moderate levels of N over time had effects similar to short-term application of high N doses. The climatic context also played an important role: the overall effects of N addition on plant species richness and diversity (Shannon index) were less pronounced in mountain grasslands experiencing cool rather than warm summers. Furthermore, the relative negative effect of N addition on species richness was more pronounced in managed communities and was strongly negatively related to N-induced increases in phytomass, that is the greater the phytomass response to N addition, the greater the decline in richness. Altogether, this review not only establishes that plant biodiversity of mountain grasslands is negatively affected by N addition, but also demonstrates that several local management and abiotic factors interact with N addition to drive plant community changes. This synthesis yields essential information for a more sustainable management of mountain grasslands, emphasizing the importance of preserving and restoring grasslands with both low

  20. 49 CFR 260.25 - Additional information for Applicants not having a credit rating.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... corresponding to those used in this section, the following information: (a) A narrative statement detailing...; and (f) A narrative description of Applicant's management team, including: (1) Rail experience of top... narrative description of Applicant's workforce and the historical rate of employee turnover....

  1. 49 CFR 260.25 - Additional information for Applicants not having a credit rating.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... corresponding to those used in this section, the following information: (a) A narrative statement detailing...; and (f) A narrative description of Applicant's management team, including: (1) Rail experience of top... narrative description of Applicant's workforce and the historical rate of employee turnover....

  2. Material Development for Tooling Applications Using Big Area Additive Manufacturing (BAAM)

    SciTech Connect

    Duty, Chad E.; Drye, Tom; Franc, Alan

    2015-03-01

    Techmer Engineered Solutions (TES) is working with Oak Ridge National Laboratory (ORNL) to develop materials and evaluate their use for ORNL s recently developed Big Area Additive Manufacturing (BAAM) system for tooling applications. The first phase of the project established the performance of some commercially available polymer compositions deposited with the BAAM system. Carbon fiber reinforced ABS demonstrated a tensile strength of nearly 10 ksi, which is sufficient for a number of low temperature tooling applications.

  3. Power Calculations for General Linear Multivariate Models Including Repeated Measures Applications.

    PubMed

    Muller, Keith E; Lavange, Lisa M; Ramey, Sharon Landesman; Ramey, Craig T

    1992-12-01

    Recently developed methods for power analysis expand the options available for study design. We demonstrate how easily the methods can be applied by (1) reviewing their formulation and (2) describing their application in the preparation of a particular grant proposal. The focus is a complex but ubiquitous setting: repeated measures in a longitudinal study. Describing the development of the research proposal allows demonstrating the steps needed to conduct an effective power analysis. Discussion of the example also highlights issues that typically must be considered in designing a study. First, we discuss the motivation for using detailed power calculations, focusing on multivariate methods in particular. Second, we survey available methods for the general linear multivariate model (GLMM) with Gaussian errors and recommend those based on F approximations. The treatment includes coverage of the multivariate and univariate approaches to repeated measures, MANOVA, ANOVA, multivariate regression, and univariate regression. Third, we describe the design of the power analysis for the example, a longitudinal study of a child's intellectual performance as a function of mother's estimated verbal intelligence. Fourth, we present the results of the power calculations. Fifth, we evaluate the tradeoffs in using reduced designs and tests to simplify power calculations. Finally, we discuss the benefits and costs of power analysis in the practice of statistics. We make three recommendations: Align the design and hypothesis of the power analysis with the planned data analysis, as best as practical.Embed any power analysis in a defensible sensitivity analysis.Have the extent of the power analysis reflect the ethical, scientific, and monetary costs. We conclude that power analysis catalyzes the interaction of statisticians and subject matter specialists. Using the recent advances for power analysis in linear models can further invigorate the interaction. PMID:24790282

  4. 41 CFR 301-74.16 - What must be included in any advertisement or application form relating to conference attendance?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What must be included in any advertisement or application form relating to conference attendance? 301-74.16 Section 301-74.16... included in any advertisement or application form relating to conference attendance? (a) Any...

  5. Uv-Light Stabilization Additive Package For Solar Cell Module And Laminated Glass Applications

    DOEpatents

    Hanoka, Jack I.; Klemchuk, Peter P.

    2002-03-05

    An ultraviolet light stabilization additive package is used in an encapsulant material that may be used in solar cell modules, laminated glass and a variety of other applications. The ultraviolet light stabilization additive package comprises a first hindered amine light stabilizer and a second hindered amine light stabilizer. The first hindered amine light stabilizer provides thermal oxidative stabilization, and the second hindered amine light stabilizer providing photo-oxidative stabilization.

  6. 33 CFR 148.105 - What must I include in my application?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: GENERAL Application for a License § 148.105 What must... participated in the decision to apply for a license to build a deepwater port; (3) A description of how each...) Experience in matters relating to deepwater ports. (1) A description of the applicant's, affiliate's,...

  7. 33 CFR 148.105 - What must I include in my application?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: GENERAL Application for a License § 148.105 What must... participated in the decision to apply for a license to build a deepwater port; (3) A description of how each...) Experience in matters relating to deepwater ports. (1) A description of the applicant's, affiliate's,...

  8. 29 CFR 2570.34 - Information to be included in every exemption application.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... with the matters discussed in this application and, to the best of my knowledge and belief, the...; (C) A designated officer or official where the applicant is an association, organization or other... knowledge and belief, the representations made in such statement are true and correct. (c) An...

  9. 7 CFR 1437.501 - Applicability; definition of “tropical region” and additional definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Applicability; definition of âtropical regionâ and additional definitions. 1437.501 Section 1437.501 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER...

  10. 7 CFR 1437.501 - Applicability; definition of “tropical region” and additional definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Applicability; definition of âtropical regionâ and additional definitions. 1437.501 Section 1437.501 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER...

  11. 10 CFR 52.80 - Contents of applications; additional technical information.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    .... 52.80 Section 52.80 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined Licenses § 52.80 Contents of applications; additional technical... environmental report, either in accordance with 10 CFR 51.50(c) if a limited work authorization under 10 CFR...

  12. 10 CFR 52.80 - Contents of applications; additional technical information.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... 52.80 Section 52.80 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined Licenses § 52.80 Contents of applications; additional technical... environmental report, either in accordance with 10 CFR 51.50(c) if a limited work authorization under 10 CFR...

  13. 10 CFR 52.80 - Contents of applications; additional technical information.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .... 52.80 Section 52.80 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined Licenses § 52.80 Contents of applications; additional technical... environmental report, either in accordance with 10 CFR 51.50(c) if a limited work authorization under 10 CFR...

  14. 10 CFR 52.80 - Contents of applications; additional technical information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... 52.80 Section 52.80 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined Licenses § 52.80 Contents of applications; additional technical... environmental report, either in accordance with 10 CFR 51.50(c) if a limited work authorization under 10 CFR...

  15. 10 CFR 52.80 - Contents of applications; additional technical information.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... 52.80 Section 52.80 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined Licenses § 52.80 Contents of applications; additional technical... environmental report, either in accordance with 10 CFR 51.50(c) if a limited work authorization under 10 CFR...

  16. 21 CFR 1311.150 - Additional requirements for internal application audits.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Additional requirements for internal application audits. 1311.150 Section 1311.150 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE... determination of such is feasible. (2) Attempted unauthorized modification or destruction of any information...

  17. 21 CFR 1311.150 - Additional requirements for internal application audits.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Additional requirements for internal application audits. 1311.150 Section 1311.150 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE... determination of such is feasible. (2) Attempted unauthorized modification or destruction of any information...

  18. 34 CFR 206.20 - What must be included in an application?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... ENGAGED IN MIGRANT AND OTHER SEASONAL FARMWORK-HIGH SCHOOL EQUIVALENCY PROGRAM AND COLLEGE ASSISTANCE... subpart C of 34 CFR part 75 (EDGAR-Direct Grant Programs); (b) Submit a grant application that: (1)...

  19. 34 CFR 206.20 - What must be included in an application?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... ENGAGED IN MIGRANT AND OTHER SEASONAL FARMWORK-HIGH SCHOOL EQUIVALENCY PROGRAM AND COLLEGE ASSISTANCE... subpart C of 34 CFR part 75 (EDGAR-Direct Grant Programs); (b) Submit a grant application that: (1)...

  20. 34 CFR 206.20 - What must be included in an application?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... ENGAGED IN MIGRANT AND OTHER SEASONAL FARMWORK-HIGH SCHOOL EQUIVALENCY PROGRAM AND COLLEGE ASSISTANCE... subpart C of 34 CFR part 75 (EDGAR-Direct Grant Programs); (b) Submit a grant application that: (1)...

  1. 34 CFR 206.20 - What must be included in an application?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ENGAGED IN MIGRANT AND OTHER SEASONAL FARMWORK-HIGH SCHOOL EQUIVALENCY PROGRAM AND COLLEGE ASSISTANCE... subpart C of 34 CFR part 75 (EDGAR-Direct Grant Programs); (b) Submit a grant application that: (1)...

  2. 34 CFR 206.20 - What must be included in an application?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ENGAGED IN MIGRANT AND OTHER SEASONAL FARMWORK-HIGH SCHOOL EQUIVALENCY PROGRAM AND COLLEGE ASSISTANCE... subpart C of 34 CFR part 75 (EDGAR-Direct Grant Programs); (b) Submit a grant application that: (1)...

  3. Application of symbolic computation to the analysis of mechanical systems, including robot arms

    NASA Technical Reports Server (NTRS)

    Hussain, M. A.; Noble, B.

    1984-01-01

    This paper illustrates the application of symbolic computation in connection with three aspects of mechanical systems: (1) The derivation of dynamical equations by Lagrangian methods; (2) The analysis and synthesis of kinematic mechanisms; and (3) A robot manipulator arm.

  4. 30 CFR 285.906 - What must my decommissioning application include?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... including: (1) Lease operator, ROW grant holder, or RUE grant holder; (2) Address; (3) Contact person and... decommissioning schedule for your lease, ROW grant, or RUE grant, including the expiration or relinquishment...

  5. A novel classification and online platform for planning and documentation of medical applications of additive manufacturing.

    PubMed

    Tuomi, Jukka; Paloheimo, Kaija-Stiina; Vehviläinen, Juho; Björkstrand, Roy; Salmi, Mika; Huotilainen, Eero; Kontio, Risto; Rouse, Stephen; Gibson, Ian; Mäkitie, Antti A

    2014-12-01

    Additive manufacturing technologies are widely used in industrial settings and now increasingly also in several areas of medicine. Various techniques and numerous types of materials are used for these applications. There is a clear need to unify and harmonize the patterns of their use worldwide. We present a 5-class system to aid planning of these applications and related scientific work as well as communication between various actors involved in this field. An online, matrix-based platform and a database were developed for planning and documentation of various solutions. This platform will help the medical community to structurally develop both research innovations and clinical applications of additive manufacturing. The online platform can be accessed through http://www.medicalam.info. PMID:24616012

  6. A novel classification and online platform for planning and documentation of medical applications of additive manufacturing.

    PubMed

    Tuomi, Jukka; Paloheimo, Kaija-Stiina; Vehviläinen, Juho; Björkstrand, Roy; Salmi, Mika; Huotilainen, Eero; Kontio, Risto; Rouse, Stephen; Gibson, Ian; Mäkitie, Antti A

    2014-12-01

    Additive manufacturing technologies are widely used in industrial settings and now increasingly also in several areas of medicine. Various techniques and numerous types of materials are used for these applications. There is a clear need to unify and harmonize the patterns of their use worldwide. We present a 5-class system to aid planning of these applications and related scientific work as well as communication between various actors involved in this field. An online, matrix-based platform and a database were developed for planning and documentation of various solutions. This platform will help the medical community to structurally develop both research innovations and clinical applications of additive manufacturing. The online platform can be accessed through http://www.medicalam.info.

  7. [FADCC in NIHS for prior consultation system of application of food additives].

    PubMed

    Akiyama, Hiroshi; Sato, Kyoko

    2015-01-01

    An increasing number of inquiries about application of food additives have been made from businesses in and outside Japan. The Ministry of Health, Labour and Welfare (MHLW) is requested to expedite the procedure for designation and revision of use standards. In June 2014, the MHLW set up a center for consultation on application concerning food additives (Food Additive Designation Consultation Center, FADCC) in the National Institute of Health Sciences, aiming to smoothly and expeditiously handle clerical work for designation or revision of the use standards. FADCC gives advice on how to prepare documents on the information such as physicochemical characteristics, effectiveness, safety, daily intake and use standards, based on actual cases and experience. PMID:26821465

  8. 40 CFR 1060.205 - What must I include in my application?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... which your certification is limited. For example, if your fuel system meets the emission requirements of this part applicable only to handheld Small SI equipment, state that the requested certificate would apply only for handheld Small SI equipment. (f) Identify the emission family's useful life. (g)...

  9. 40 CFR 1060.205 - What must I include in my application?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... which your certification is limited. For example, if your fuel system meets the emission requirements of this part applicable only to handheld Small SI equipment, state that the requested certificate would apply only for handheld Small SI equipment. (f) Identify the emission family's useful life. (g)...

  10. 40 CFR 1060.205 - What must I include in my application?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... which your certification is limited. For example, if your fuel system meets the emission requirements of this part applicable only to handheld Small SI equipment, state that the requested certificate would apply only for handheld Small SI equipment. (f) Identify the emission family's useful life. (g)...

  11. 40 CFR 1060.205 - What must I include in my application?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... which your certification is limited. For example, if your fuel system meets the emission requirements of this part applicable only to handheld Small SI equipment, state that the requested certificate would apply only for handheld Small SI equipment. (f) Identify the emission family's useful life. (g)...

  12. 29 CFR 2570.35 - Information to be included in applications for individual exemptions only.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... reflected in the plan's most recent annual report; (iii) The approximate percentage of the fair market value...) A copy of the most recent financial statements of each plan affected by the requested exemption; and... to the transaction upon discovery of the violation; (vii) That the applicant has submitted...

  13. 29 CFR 2570.35 - Information to be included in applications for individual exemptions only.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... reflected in the plan's most recent annual report; (iii) The approximate percentage of the fair market value...) A copy of the most recent financial statements of each plan affected by the requested exemption; and... to the transaction upon discovery of the violation; (vii) That the applicant has submitted...

  14. Extended weighted fair queuing (EWFQ) algorithm for broadband applications including multicast traffic

    NASA Astrophysics Data System (ADS)

    Tufail, Mudassir; Cousin, Bernard

    1997-10-01

    Ensuring end-to-end bounded delay and fair allocation of bandwidth to a backlogged session are no more the only criterias for declaring a queue service scheme good. With the evolution of packet-switched networks, more and more distributed and multimedia applications are being developed. These applications demand that service offered to them should be homogeneously distributed at all instants contrarily to back-to-back packet's serving in WFQ scheme. There are two reasons for this demand of homogeneous service: (1) In feedback based congestion control algorithms, sources constantly sample the network state using the feedback from the receiver. The source modifies its emission rate in accordance to the feedback message. A reliable feedback message is only possible if the packet service is homogeneous. (2) In multicast applications, where packet replication is performed at switches, replicated packets are probable to be served at different rates if service to them, at different output ports, is not homogeneous. This is not desirable for such applications as the phenomena of packet replication to different multicast branches, at a switch, has to be carried out at a homogeneous speed for the following two important reasons: (1) heterogeneous service rates of replicated multicast packets result in different feedback informations, from different destinations (of same multicast session), and thus lead to unstable and less efficient network control. (2) in a switch architecture, the buffer requirement can be reduced if replication and serving of multicast packets are done at a homogeneous rate. Thus, there is a need of a service discipline which not only serve the applications at no less than their guaranteed rates but also assures a homogeneous service to packets. The homogeneous service to an application may precisely be translated in terms of maintaining a good inter-packets spacing. EWFQ scheme is identical to WFQ scheme expect that a packet is stamped with delayed

  15. 34 CFR 607.11 - What must be included in individual development grant applications?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Does an Institution Apply for a Grant? § 607.11 What must be included in individual development grant... development grant must include— (a) The institution's comprehensive development plan; (b) A description of the... 34 Education 3 2010-07-01 2010-07-01 false What must be included in individual development...

  16. 40 CFR 1036.205 - What must I include in my application?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW AND IN-USE HEAVY-DUTY HIGHWAY ENGINES Certifying Engine... described in 40 CFR 86.007-21, with the following additional information: (a) Describe the engine family's... with the requirements of this part. Describe in detail all system components for controlling...

  17. 40 CFR 1036.205 - What must I include in my application?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW AND IN-USE HEAVY-DUTY HIGHWAY ENGINES Certifying Engine... described in 40 CFR 86.007-21, with the following additional information: (a) Describe the engine family's... with the requirements of this part. Describe in detail all system components for controlling...

  18. 45 CFR 2517.410 - What must a qualified organization include in an application for a grant or a subgrant?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... fiscal audits and program evaluation; (ii) Comply with the nonduplication, nondisplacement, and grievance... PROGRAMS Application Contents § 2517.410 What must a qualified organization include in an application for a... organization must submit the following: (1) A plan describing the goals and activities of the proposed...

  19. 30 CFR 585.906 - What must my decommissioning application include?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... grant holder, or RUE grant holder; (2) Address; (3) Contact person and telephone number; and (4) Shore... lease, ROW grant, or RUE grant, including the expiration or relinquishment date and proposed month...

  20. 30 CFR 585.906 - What must my decommissioning application include?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... operator, ROW grant holder, or RUE grant holder; (2) Address; (3) Contact person and telephone number; and... schedule for your lease, ROW grant, or RUE grant, including the expiration or relinquishment date...

  1. 30 CFR 285.906 - What must my decommissioning application include?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... grant holder, or RUE grant holder; (2) Address; (3) Contact person and telephone number; and (4) Shore... lease, ROW grant, or RUE grant, including the expiration or relinquishment date and proposed month...

  2. 30 CFR 585.906 - What must my decommissioning application include?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... grant holder, or RUE grant holder; (2) Address; (3) Contact person and telephone number; and (4) Shore... lease, ROW grant, or RUE grant, including the expiration or relinquishment date and proposed month...

  3. Including xpc® feed additive in the diet of inoculated broilers during grow-out helps control salmonella associated with their carcasses after processing

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The objective of this study was to test XPC® feed additive for control of Salmonella in poultry meat products. Day of hatch broiler chicks were gavaged with 106 cells of a nalidixic acid resistant marker strain of Salmonella Typhimurium and placed on clean pine shavings in 9 separate floor pens (25 ...

  4. Transport in Nanoporous Materials Including MOFs: The Applicability of Fick's Laws.

    PubMed

    Titze, Tobias; Lauerer, Alexander; Heinke, Lars; Chmelik, Christian; Zimmermann, Nils E R; Keil, Frerich J; Ruthven, Douglas M; Kärger, Jörg

    2015-11-23

    Diffusion in nanoporous host-guest systems is often considered to be too complicated to comply with such "simple" relationships as Fick's first and second law of diffusion. However, it is shown herein that the microscopic techniques of diffusion measurement, notably the pulsed field gradient (PFG) technique of NMR spectroscopy and microimaging by interference microscopy (IFM) and IR microscopy (IRM), provide direct experimental evidence of the applicability of Fick's laws to such systems. This remains true in many situations, even when the detailed mechanism is complex. The limitations of the diffusion model are also discussed with reference to the extensive literature on this subject.

  5. Neural Mechanisms Underlying Musical Pitch Perception and Clinical Applications Including Developmental Dyslexia.

    PubMed

    Yuskaitis, Christopher J; Parviz, Mahsa; Loui, Psyche; Wan, Catherine Y; Pearl, Phillip L

    2015-08-01

    Music production and perception invoke a complex set of cognitive functions that rely on the integration of sensorimotor, cognitive, and emotional pathways. Pitch is a fundamental perceptual attribute of sound and a building block for both music and speech. Although the cerebral processing of pitch is not completely understood, recent advances in imaging and electrophysiology have provided insight into the functional and anatomical pathways of pitch processing. This review examines the current understanding of pitch processing and behavioral and neural variations that give rise to difficulties in pitch processing, and potential applications of music education for language processing disorders such as dyslexia. PMID:26092314

  6. 29 CFR 2570.34 - Information to be included in every exemption application.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the party in interest or its affiliate(s) may derive from control of the asset(s), such as from owning... disclosing the percentage of its current revenue that is derived from any party in interest involved in the... (including amounts received from preparing the appraisal report) that will be derived from the party...

  7. 29 CFR 2570.34 - Information to be included in every exemption application.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the party in interest or its affiliate(s) may derive from control of the asset(s), such as from owning... disclosing the percentage of its current revenue that is derived from any party in interest involved in the... (including amounts received from preparing the appraisal report) that will be derived from the party...

  8. 25 CFR 1000.66 - What must be included in the application?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... EDUCATION ACT Other Financial Assistance for Planning and Negotiation Grants for Non-BIA Programs... planning and negotiation grant must include: (a) Written notification by the governing body or its authorized representative of the Tribe's/Consortium's intent to engage in planning/negotiation...

  9. 77 FR 64768 - Regulations Regarding the Application of Section 172(h) Including Consolidated Groups; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-23

    ..., 2012 (77 FR 57452). The proposed regulation provides guidance regarding the treatment of corporate... (REG-140668-07), that was the subject of FR Doc. 2012-22838, is corrected as follows: 1. On page 57452...) Including Consolidated Groups; Correction AGENCY: Internal Revenue Service (IRS), Treasury....

  10. 40 CFR 1039.205 - What must I include in my application?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... fuel to show that it falls within the required ranges we specify in 40 CFR part 1065. (h) Identify the... your tests were valid under the requirements of this part and 40 CFR part 1065. (2) Report measured CO2... parts of the CFR, and the Clean Air Act. (x) Include good-faith estimates of U.S.-directed...

  11. 40 CFR 1037.205 - What must I include in my application?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... fuel to show that it falls within the required ranges we specify in 40 CFR part 1065. (h) Identify the... and 40 CFR part 86. (o) Report modeling results for ten configurations. Include modeling inputs and... comply with the requirements of this part, other referenced parts of the CFR, and the Clean Air Act....

  12. 40 CFR 1037.205 - What must I include in my application?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... fuel to show that it falls within the required ranges we specify in 40 CFR part 1065. (h) Identify the... and 40 CFR part 86. (o) Report modeling results for ten configurations. Include modeling inputs and... comply with the requirements of this part, other referenced parts of the CFR, and the Clean Air Act....

  13. 40 CFR 1039.205 - What must I include in my application?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... and how the modulation achieves the AECD's stated purpose. Use graphs and tables, as necessary. (8) Describe each AECD's specific calibration details. This may be in the form of data tables, graphical... § 1039.501). (f) Describe how you operated the emission-data engine before testing, including the...

  14. 40 CFR 1039.205 - What must I include in my application?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... and how the modulation achieves the AECD's stated purpose. Use graphs and tables, as necessary. (8) Describe each AECD's specific calibration details. This may be in the form of data tables, graphical...) Describe how you operated the emission-data engine before testing, including the duty cycle and the...

  15. 40 CFR 1039.205 - What must I include in my application?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... and how the modulation achieves the AECD's stated purpose. Use graphs and tables, as necessary. (8) Describe each AECD's specific calibration details. This may be in the form of data tables, graphical...) Describe how you operated the emission-data engine before testing, including the duty cycle and the...

  16. 40 CFR 1039.205 - What must I include in my application?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... and how the modulation achieves the AECD's stated purpose. Use graphs and tables, as necessary. (8) Describe each AECD's specific calibration details. This may be in the form of data tables, graphical...) Describe how you operated the emission-data engine before testing, including the duty cycle and the...

  17. Integrative Biological Chemistry Program Includes the Use of Informatics Tools, GIS and SAS Software Applications

    ERIC Educational Resources Information Center

    D'Souza, Malcolm J.; Kashmar, Richard J.; Hurst, Kent; Fiedler, Frank; Gross, Catherine E.; Deol, Jasbir K.; Wilson, Alora

    2015-01-01

    Wesley College is a private, primarily undergraduate minority-serving institution located in the historic district of Dover, Delaware (DE). The College recently revised its baccalaureate biological chemistry program requirements to include a one-semester Physical Chemistry for the Life Sciences course and project-based experiential learning…

  18. 40 CFR 1054.205 - What must I include in my application?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... emission control systems operate. Describe the evaporative emission controls and show how your design will... controlling exhaust emissions, including all auxiliary emission control devices (AECDs) and all fuel-system... specified in 40 CFR part 1068, Appendix III. For example, engine owners should have ready access...

  19. 49 CFR 107.709 - Processing of an application for approval, including an application for renewal or modification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... consistent with the public interest and adequately will protect against the risks to life and property inherent in the transportation of hazardous materials in commerce; (3) The application states all...

  20. 40 CFR 1051.225 - How do I amend my application for certification to include new or modified vehicle configurations...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... certification to include new or modified vehicle configurations or to change an FEL? 1051.225 Section 1051.225... application for certification to include new or modified vehicle configurations or to change an FEL? Before we... FEL for an engine family, as described in paragraph (f) of this section. (b) To amend your...

  1. 40 CFR 1051.225 - How do I amend my application for certification to include new or modified vehicle configurations...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... certification to include new or modified vehicle configurations or to change an FEL? 1051.225 Section 1051.225... application for certification to include new or modified vehicle configurations or to change an FEL? Before we... FEL for an engine family, as described in paragraph (f) of this section. (b) To amend your...

  2. 40 CFR 1051.225 - How do I amend my application for certification to include new or modified vehicle configurations...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... certification to include new or modified vehicle configurations or to change an FEL? 1051.225 Section 1051.225... application for certification to include new or modified vehicle configurations or to change an FEL? Before we... FEL for an engine family, as described in paragraph (f) of this section. (b) To amend your...

  3. 40 CFR 1051.225 - How do I amend my application for certification to include new or modified vehicle configurations...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... certification to include new or modified vehicle configurations or to change an FEL? 1051.225 Section 1051.225... application for certification to include new or modified vehicle configurations or to change an FEL? Before we... FEL for an engine family, as described in paragraph (f) of this section. (b) To amend your...

  4. Advances in the theory and application of BSF cells. [including electrical resistivity and photovoltaic cells

    NASA Technical Reports Server (NTRS)

    Mandelkorn, J.; Lamneck, J. H.

    1975-01-01

    The characteristics and behavior of p(+), p solar cells were investigated. The p(+), p cells were made by the removal of the n(+) surface layers from n(+), p p(+), BSF cells followed by application of a suitable contact to the resultant p(+), p structures. The open circuit voltage of p(+), p cells was found to increase with increasing 'p' bulk resistivity. The measured open circuit velocity-temperature coefficients were positive and increased with increasing resistivity. An outline of prior limitations in solar cell design is presented, and the removal of these limitations through use of BSF effects is pointed out. The study of BSF effects made feasible production of very thin high efficiency silicon cells as well as high resistivity-high efficiency cells, two desirable types of silicon cells which were previously impossible to make.

  5. Quantum ring-polymer contraction method: Including nuclear quantum effects at no additional computational cost in comparison to ab initio molecular dynamics.

    PubMed

    John, Christopher; Spura, Thomas; Habershon, Scott; Kühne, Thomas D

    2016-04-01

    We present a simple and accurate computational method which facilitates ab initio path-integral molecular dynamics simulations, where the quantum-mechanical nature of the nuclei is explicitly taken into account, at essentially no additional computational cost in comparison to the corresponding calculation using classical nuclei. The predictive power of the proposed quantum ring-polymer contraction method is demonstrated by computing various static and dynamic properties of liquid water at ambient conditions using density functional theory. This development will enable routine inclusion of nuclear quantum effects in ab initio molecular dynamics simulations of condensed-phase systems. PMID:27176426

  6. Quantum ring-polymer contraction method: Including nuclear quantum effects at no additional computational cost in comparison to ab initio molecular dynamics

    NASA Astrophysics Data System (ADS)

    John, Christopher; Spura, Thomas; Habershon, Scott; Kühne, Thomas D.

    2016-04-01

    We present a simple and accurate computational method which facilitates ab initio path-integral molecular dynamics simulations, where the quantum-mechanical nature of the nuclei is explicitly taken into account, at essentially no additional computational cost in comparison to the corresponding calculation using classical nuclei. The predictive power of the proposed quantum ring-polymer contraction method is demonstrated by computing various static and dynamic properties of liquid water at ambient conditions using density functional theory. This development will enable routine inclusion of nuclear quantum effects in ab initio molecular dynamics simulations of condensed-phase systems.

  7. FUNDAMENTAL AREAS OF PHENOMENOLOGY (INCLUDING APPLICATIONS): Small-Pitch Kagome Hollow-Core Photonic Crystal Fibre

    NASA Astrophysics Data System (ADS)

    Meng, Jia; Hou, Lan-Tian; Zhou, Gui-Yao; Wang, Kang; Chen, Chao

    2008-08-01

    A hollow-core photonic crystal fibre (HC-PCF) based on small-pitch kagome lattice cladding is designed and fabricated. The pitch of the fibre is only 2.45μm and it corresponds to a region of low normalized frequency which has never been investigated before. Both experiments and calculations show that this kagome HC-PCF has a broad optical transmission band from 400 nm to 900 nm, covering the whole visible and near infrared region of the spectrum. Additionally, the loss curve of the fibre is flat in the visible region and the minimum of the loss achieves 0.16dB/m, which is lower than the loss of the kagome HC-PCFs reported before. Furthermore, this fibre can well confine the modes in the air core. No surface modes can be detected in the surrounding silica of the hollow core.

  8. Including aortic valve morphology in computational fluid dynamics simulations: initial findings and application to aortic coarctation.

    PubMed

    Wendell, David C; Samyn, Margaret M; Cava, Joseph R; Ellwein, Laura M; Krolikowski, Mary M; Gandy, Kimberly L; Pelech, Andrew N; Shadden, Shawn C; LaDisa, John F

    2013-06-01

    Computational fluid dynamics (CFD) simulations quantifying thoracic aortic flow patterns have not included disturbances from the aortic valve (AoV). 80% of patients with aortic coarctation (CoA) have a bicuspid aortic valve (BAV) which may cause adverse flow patterns contributing to morbidity. Our objectives were to develop a method to account for the AoV in CFD simulations, and quantify its impact on local hemodynamics. The method developed facilitates segmentation of the AoV, spatiotemporal interpolation of segments, and anatomic positioning of segments at the CFD model inlet. The AoV was included in CFD model examples of a normal (tricuspid AoV) and a post-surgical CoA patient (BAV). Velocity, turbulent kinetic energy (TKE), time-averaged wall shear stress (TAWSS), and oscillatory shear index (OSI) results were compared to equivalent simulations using a plug inlet profile. The plug inlet greatly underestimated TKE for both examples. TAWSS differences extended throughout the thoracic aorta for the CoA BAV, but were limited to the arch for the normal example. OSI differences existed mainly in the ascending aorta for both cases. The impact of AoV can now be included with CFD simulations to identify regions of deleterious hemodynamics thereby advancing simulations of the thoracic aorta one step closer to reality. PMID:22917990

  9. Study Modules for Calculus-Based General Physics. [Includes Modules 1 and 2: Dimensions and Vector Addition; Rectilinear Motion; plus a Trigonometry and Calculus Review].

    ERIC Educational Resources Information Center

    Fuller, Robert G., Ed.; And Others

    This is part of a series of 42 Calculus Based Physics (CBP) modules totaling about 1,000 pages. The modules include study guides, practice tests, and mastery tests for a full-year individualized course in calculus-based physics based on the Personalized System of Instruction (PSI). The units are not intended to be used without outside materials;…

  10. 75 FR 35119 - 60-Day Notice of Proposed Information Collection: Form DS-4085 Application for Additional Visa...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-21

    ... Notice of Proposed Information Collection: Form DS-4085 Application for Additional Visa Pages or... the Paperwork Reduction Act of 1995. Title of Information Collection: Application for Additional Visa... collection: The information collected on the DS-4085 is used to facilitate the issuance of additional...

  11. 40 CFR 122.42 - Additional conditions applicable to specified categories of NPDES permits (applicable to State...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... requirement to implement a nutrient management plan that, at a minimum, contains best management practices..., including those specified in 40 CFR part 412. The nutrient management plan must, to the extent applicable...; (vii) Identify protocols for appropriate testing of manure, litter, process wastewater, and soil;...

  12. 40 CFR 122.42 - Additional conditions applicable to specified categories of NPDES permits (applicable to State...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... requirement to implement a nutrient management plan that, at a minimum, contains best management practices..., including those specified in 40 CFR part 412. The nutrient management plan must, to the extent applicable...; (vii) Identify protocols for appropriate testing of manure, litter, process wastewater, and soil;...

  13. 40 CFR 122.42 - Additional conditions applicable to specified categories of NPDES permits (applicable to State...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... requirement to implement a nutrient management plan that, at a minimum, contains best management practices..., including those specified in 40 CFR part 412. The nutrient management plan must, to the extent applicable...; (vii) Identify protocols for appropriate testing of manure, litter, process wastewater, and soil;...

  14. 40 CFR 122.42 - Additional conditions applicable to specified categories of NPDES permits (applicable to State...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... requirement to implement a nutrient management plan that, at a minimum, contains best management practices..., including those specified in 40 CFR part 412. The nutrient management plan must, to the extent applicable...; (vii) Identify protocols for appropriate testing of manure, litter, process wastewater, and soil;...

  15. 40 CFR 122.42 - Additional conditions applicable to specified categories of NPDES permits (applicable to State...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... requirement to implement a nutrient management plan that, at a minimum, contains best management practices..., including those specified in 40 CFR part 412. The nutrient management plan must, to the extent applicable...; (vii) Identify protocols for appropriate testing of manure, litter, process wastewater, and soil;...

  16. Localization of eight additional genes in the human major histocompatibility complex, including the gene encoding the casein kinase II {beta} subunit (CSNK2B)

    SciTech Connect

    Albertella, M.R.; Jones, H.; Thomson, W.

    1996-09-01

    A wide range of autoimmune and other diseases are known to be associated with the major histocompatibility complex. Many of these diseases are linked to the genes encoding the polymorphic histocompatibility complex. Many of these diseases are linked to the genes encoding the polymorphic histocompatibility antigens in the class I and class II regions, but some appear to be more strongly associated with genes in the central 1100-kb class III region, making it important to characterize this region fully for the presence of novel genes. An {approximately}220-kb segment of DNA in the class III region separating the Hsp70 (HSPA1L) and BAT1 (D6S8IE) genes, which was previously known to contain 14 genes. Genomic DNA fragments spanning the gaps between the known genes were used as probes to isolate cDNAs corresponding to five new genes within this region. Evidence from Northern blot analysis and exon trapping experiments that suggested the presence of at least two more new genes was also obtained. Partial cDNA and complete exonic genomic sequencing of one of the new genes has identified it as the casein kinase II{beta} subunit (CSNK2B). Two of the other novel genes lie within a region syntenic to that implicated in susceptibility to experimental allergic orchitis in the mouse, an autoimmune disease of the testis, and represent additional candidates for the Orch-1 locus associated with this disease. In addition, characterization of the 13-kb intergenic gap separating the RD (D6545) and G11 (D6S60E) genes has revealed the presence of a gene encoding a 1246-amino-acid polypeptide that shows significant sequence similarity to the yeast anti-viral Ski2p gene product. 49 refs., 8 figs.

  17. Effect of silver addition on the properties of nickel-titanium alloys for dental application.

    PubMed

    Oh, Keun-Taek; Joo, Uk-Hyon; Park, Gee-Ho; Hwang, Chung-Ju; Kim, Kyoung-Nam

    2006-02-01

    Equiatomic and near-equiatomic nickel-titanium alloys exhibit a shape-memory effect and superelasticity. However, the properties of such alloys are extremely sensitive to the precise nickel-titanium ratio and the addition of alloying elements. High corrosion resistance is necessary for biomedical applications, especially orthodontic. The purpose of this study was to investigate the effect of silver addition to nickel-titanium alloys for dental and medical application. Arc melting, homogenization, hot rolling, and solution heat treatment were performed to prepare the nickel-titanium-silver (NiTi-Ag) specimens. The properties of the ternary NiTi-Ag alloys such as phase-transformation temperature, microstructure, microhardness, corrosion resistance, and cytotoxicity were investigated. The NiTi-Ag alloys showed low silver recovery rate for the cast alloy, due to silver's low evaporation temperature, and low silver solubility in nickel-titanium. Silver addition to nickel-titanium increased the transition temperature range to 100 degrees C and stabilized the martensitic phase (monoclinic structure) at room temperature, because the martensitic transformation starting temperature (Ms) was above room temperature. Martensitic and austenitic phases existed in X-ray diffraction patterns of solution-annealed NiTi-Ag alloys. The silver addition was considered to improve the corrosion resistance and form a stable passive film. Significantly, the mechanical properties of the silver-added alloys were dependent upon the amount of alloying addition. There was no toxicity in the NiTi-Ag alloys, as the response index showed none or mild levels.

  18. Direct design of a two-surface lens including an entrance pupil for imaging applications

    NASA Astrophysics Data System (ADS)

    Nie, Yunfeng; Duerr, Fabian; Thienpont, Hugo

    2015-09-01

    A multi-fields optical design method aiming to calculate two high-order aspheric lens profiles simultaneously with an embedded entrance pupil is proposed in this paper. The Simultaneous Multiple Surfaces design method in two dimensions (SMS2D) is used to provide a better understanding of how N surfaces allow perfect coupling of N ray-bundles. In contract to this perfect coupling, our multi-fields design approach is based on the partial coupling of multiple ray-bundles. This method allows calculating the Optical Path Lengths (OPL) during the process, directly building connections between different fields of view. Both infinite and finite conjugate objectives can be designed with this approach. Additional constraints like surface continuity and smoothness are taken into account to calculate two smooth and accurate surface contours. Sub-aperture sampling factor is introduced as a weighting function for different fields which allows for a very flexible performance control over a wide field of view. A RMS 2D spot size function is used to optimize the weighting factor to achieve a very well-balanced imaging performance. A wide-field objective and a moderate aperture lens are designed and analyzed to demonstrate the potential of this design method. The impact of different weighting functions for the sub-aperture sampling is evaluated accordingly. It's shown that this design method provides an excellent starting point for further optimization of the surfaces coefficients and initial design parameters: resulting in a very good and well-balanced imaging performance over the entire field of view.

  19. Development and Application of a Nonbonded Cu2+ Model That Includes the Jahn–Teller Effect

    PubMed Central

    2015-01-01

    Metal ions are both ubiquitous to and crucial in biology. In classical simulations, they are typically described as simple van der Waals spheres, making it difficult to provide reliable force field descriptions for them. An alternative is given by nonbonded dummy models, in which the central metal atom is surrounded by dummy particles that each carry a partial charge. While such dummy models already exist for other metal ions, none is available yet for Cu2+ because of the challenge to reproduce the Jahn–Teller distortion. This challenge is addressed in the current study, where, for the first time, a dummy model including a Jahn–Teller effect is developed for Cu2+. We successfully validate its usefulness by studying metal binding in two biological systems: the amyloid-β peptide and the mixed-metal enzyme superoxide dismutase. We believe that our parameters will be of significant value for the computational study of Cu2+-dependent biological systems using classical models. PMID:26167255

  20. Petrographic and Geochemical Characterization of Ore-Bearing Intrusions of the Noril'sk type, Siberia; With Discussion of Their Origin, Including Additional Datasets and Core Logs

    USGS Publications Warehouse

    Czamanske, Gerald K.

    2002-01-01

    The Noril'sk I, Talnakh, and Kharaelakh intrusions of the Noril'sk district host one of the outstanding metal concentrations in the world; contained Cu-Ni resources are comparable to the deposits at Sudbury, Ontario and the platinum group element (PGE) resource is second only to that of the Bushveld Complex. Our opportunity to cooperatively sample and study this district in Siberian Russia arose in 1990 through a memorandum of understanding between the U.S. Geological Survey and the former Ministry of Geology of the U.S.S.R. The world-class significance of these deposits and the possibility that understanding their geologic context, including construction of a credible 'ore-deposit model,' will lead to discovery of similar deposits elsewhere, inspired extensive studies of the ores, the mafic-intrusions which host them, and associated flood basalts.

  1. Uranium hydrogeochemical and stream sediment reconnaissance of the Dalhart NTMS quadrangle, New Mexico/Texas/Oklahoma, including concentrations of forty-two additional elements

    SciTech Connect

    Morgan, T.L.

    1980-08-01

    Totals of 1583 water samples and 503 sediment samples were collected from 2028 locations within the 20 000-km/sup 2/ area of the quadrangle at an average density of one location per 9.86 km/sup 2/. Water samples were collected from wells, springs, and streams and were analyzed for uranium. Sediment samples were collected from streams and springs and were analyzed for uranium, thorium, and 41 additional elements. All field and analytical data are listed in the appendixes of this report. Discussion is limited to anomalous samples, which are considered to be those containing over 20 ppB uranium for waters and over 5 ppM uranium for sediments. Uranium concentrations in water samples range from below the detection limit of 0.2 ppB to 1457.65 ppB and average 7.41 ppB. Most of the seventy anomalous water samples (4.4% of all water samples) are grouped spatially into five clusters or areas of interest. Samples in three of the clusters were collected along the north edge of the quadrangle where Mesozoic strata are exposed. The other two clusters are from the central and southern portions where the Quaternary Ogallala formation is exposed. Sediment samples from the quadrangle have uranium concentrations that range from 0.90 ppM to 27.20 ppM and average 3.27 ppM. Fourteen samples (2.8% of all sediment samples) contain over 5 ppM uranium and are considered anomalous. The five samples with the highest concentrations occur where downcutting streams expose Cretaceous units beneath the Quaternary surficial deposits. The remaining anomalous sediment samples were collected from scattered locations and do not indicate any single formation or unit as a potential source for the anomalous concentrations.

  2. Integrative Biological Chemistry Program Includes The Use Of Informatics Tools, GIS And SAS Software Applications

    PubMed Central

    D’Souza, Malcolm J.; Kashmar, Richard J.; Hurst, Kent; Fiedler, Frank; Gross, Catherine E.; Deol, Jasbir K.; Wilson, Alora

    2015-01-01

    Wesley College is a private, primarily undergraduate minority-serving institution located in the historic district of Dover, Delaware (DE). The College recently revised its baccalaureate biological chemistry program requirements to include a one-semester Physical Chemistry for the Life Sciences course and project-based experiential learning courses using instrumentation, data-collection, data-storage, statistical-modeling analysis, visualization, and computational techniques. In this revised curriculum, students begin with a traditional set of biology, chemistry, physics, and mathematics major core-requirements, a geographic information systems (GIS) course, a choice of an instrumental analysis course or a statistical analysis systems (SAS) programming course, and then, students can add major-electives that further add depth and value to their future post-graduate specialty areas. Open-sourced georeferenced census, health and health disparity data were coupled with GIS and SAS tools, in a public health surveillance system project, based on US county zip-codes, to develop use-cases for chronic adult obesity where income, poverty status, health insurance coverage, education, and age were categorical variables. Across the 48 contiguous states, obesity rates are found to be directly proportional to high poverty and inversely proportional to median income and educational achievement. For the State of Delaware, age and educational attainment were found to be limiting obesity risk-factors in its adult population. Furthermore, the 2004–2010 obesity trends showed that for two of the less densely populated Delaware counties; Sussex and Kent, the rates of adult obesity were found to be progressing at much higher proportions when compared to the national average. PMID:26191337

  3. Fabrication of SWCNT-Ag nanoparticle hybrid included self-assemblies for antibacterial applications.

    PubMed

    Brahmachari, Sayanti; Mandal, Subhra Kanti; Das, Prasanta Kumar

    2014-01-01

    The present article reports the development of soft nanohybrids comprising of single walled carbon nanotube (SWCNT) included silver nanoparticles (AgNPs) having superior antibacterial property. In this regard aqueous dispersing agent of carbon nanotube (CNT) containing a silver ion reducing unit was synthesised by the inclusion of tryptophan and tyrosine within the backbone of the amphiphile. The dispersions were characterized spectroscopically and microscopically using TEM, AFM and Raman spectroscopy. The nanotube-nanoparticle conjugates were prepared by the in situ photoreduction of AgNO3. The phenolate residue and the indole moieties of tyrosine and tryptophan, respectively reduces the sliver ion as well as acts as stabilizing agents for the synthesized AgNPs. The nanohybrids were characterized using TEM and AFM. The antibacterial activity of the nanohybrids was studied against Gram-positive (Bacillus subtilis and Micrococcus luteus) and Gram-negative bacteria (Escherichia coli and Klebsiella aerogenes). The SWCNT dispersions showed moderate killing ability (40-60%) against Gram-positive bacteria however no antibacterial activity was observed against the Gram negative ones. Interestingly, the developed SWCNT-amphiphile-AgNP nanohybrids exhibited significant killing ability (∼90%) against all bacteria. Importantly, the cell viability of these newly developed self-assemblies was checked towards chinese hamster ovarian cells and high cell viability was observed after 24 h of incubation. This specific killing of bacterial cells may have been achieved due to the presence of higher -SH containing proteins in the cell walls of the bacteria. The developed nanohybrids were subsequently infused into tissue engineering scaffold agar-gelatin films and the films similarly showed bactericidal activity towards both kinds of bacterial strains while allowing normal growth of eukaryotic cells on the surface of the films. PMID:25191756

  4. A surplus production model including environmental effects: Application to the Senegalese white shrimp stocks

    NASA Astrophysics Data System (ADS)

    Thiaw, Modou; Gascuel, Didier; Jouffre, Didier; Thiaw, Omar Thiom

    2009-12-01

    In Senegal, two stocks of white shrimp ( Penaeusnotialis) are intensively exploited, one in the north and another in the south. We used surplus production models including environmental effects to analyse their changes in abundance over the past 10 years and to estimate their Maximum Sustainable Yield (MSY) and the related fishing effort ( EMSY). First, yearly abundance indices were estimated from commercial statistics using GLM techniques. Then, two environmental indices were alternatively tested in the model: the coastal upwelling intensity from wind speeds provided by the SeaWifs database and the primary production derived from satellite infrared images of chlorophyll a. Models were fitted, with or without the environmental effect, to the 1996-2005 time series. They express stock abundance and catches as functions of the fishing effort and the environmental index (when considered). For the northern stock, fishing effort and abundance fluctuate over the period without any clear trends. The model based on the upwelling index explains 64.9% of the year-to-year variability. It shows that the stock was slightly overexploited in 2002-2003 and is now close to full exploitation. Stock abundance strongly depends on environmental conditions; consequently, the MSY estimate varies from 300 to 900 tons according to the upwelling intensity. For the southern stock, fishing effort has strongly increased over the past 10 years, while abundance has been reduced 4-fold. The environment has a significant effect on abundance but only explains a small part of the year-to-year variability. The best fit is obtained using the primary production index ( R2 = 0.75), and the stock is now significantly overfished regardless of environmental conditions. MSY varies from 1200 to 1800 tons according to environmental conditions. Finally, in northern Senegal, the upwelling is highly variable from year to year and constitutes the major factor determining productivity. In the south, hydrodynamic

  5. Graphene with outstanding anti-irradiation capacity as multialkylated cyclopentanes additive toward space application

    PubMed Central

    Fan, Xiaoqiang; Wang, Liping

    2015-01-01

    Multialkylated cyclopentanes (MACs), a class of synthetic hydrocarbon fluid have attracted intensive interest as possible space lubricants due to a series of unique physical and chemical properties. Here, we used graphene with high mechanical strength and chemical inertness as lubricant additive to explore its potential for space application. The effects of space irradiation on graphene and the tribological properties of graphene as lubricant additive were firstly investigated in detail under simulated space environment composed of high vacuum, high/low temperature and irradiation. Results demonstrate that graphene not only possesses outstanding anti–irradiation capacity but also significantly improves the space performance and tribological properties of MACs, which depends on the excellent physicochemical properties and high load-carrying ability of graphene as well as more effective separation of the sliding surfaces. PMID:26224254

  6. 12 CFR 390.128 - If the FDIC requests additional information to complete my application, how will it process my...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... complete my application, how will it process my application? 390.128 Section 390.128 Banks and Banking... additional information to complete my application, how will it process my application? (a) You may use the... will notify you that it has extended the period before the end of the initial 15-day period and...

  7. Uranium hydrogeochemical and stream sediment reconnaissance data release for the Elk City NTMS Quadrangle, Idaho/Montana, including concentrations of forty-five additional elements

    SciTech Connect

    Broxton, D.E.; Beyth, M.

    1980-07-01

    Totals of 1580 water and 1720 sediment samples were collected from 1754 locations in the quadrangle. Elemental concentration, field measurement, weather, geologic, and geographic data for each sample location are listed for waters in Appendix I-A and for sediments in Appendix I-B. Uranium/thorium ratios for sediment samples are also included in Appendix I-B. All elemental analyses were performed at the LASL. Water samples were initially analyzed for uranium by fluorometry. All water samples containing more than 40 parts per billion (ppB) uranium were reanalyzed by delayed-neutron counting (DNC). A supplemental report containing the multielement analyses of water samples will be open filed in the near future. Sediments were analyzed for uranium and thorium as well as aluminum, antimony, arsenic, barium, beryllium, bismuth, cadmium, calcium, cerium, cesium, chlorine, chromium, cobalt, copper, dysprosium, europium, gold, hafnium, iron, lanthanum, lead, lithium, lutetium, magnesium, manganese, nickel, niobium, potassium, rubidium, samarium, selenium, scandium, silver, sodium, strontium, tantalum, terbium, tin, titanium, tungsten, vanadium, ytterbium, zinc, and zirconium. Basic statistics for 40 of these elements are presented. All sediments were analyzed for uranium by delayed-neutron counting. Other elemental concentrations in sediments were determined by neutron-activation analysis for 30 elements, by x-ray fluorescence for 12 elements, and by arc-source emission spectrography for 2 elements. Analytical results for sediments are reported as parts per million.

  8. 42 CFR 493.645 - Additional fee(s) applicable to approved State laboratory programs and laboratories issued a...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS General Administration § 493.645 Additional fee(s) applicable to approved State laboratory programs...

  9. 42 CFR 493.645 - Additional fee(s) applicable to approved State laboratory programs and laboratories issued a...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS General Administration § 493.645 Additional fee(s) applicable to approved State laboratory programs...

  10. New Theoretical Developments in Exploring Electronically Excited States: Including Localized Configuration Interaction Singles and Application to Large Helium Clusters

    NASA Astrophysics Data System (ADS)

    Closser, Kristina Danielle

    superpositions of atomic states with surface states appearing close to the atomic excitation energies and interior states being blue shifted by up to ≈2 eV. The dynamics resulting from excitation of He_7 were subsequently explored using ab initio molecular dynamics (AIMD). These simulations were performed with classical adiabatic dynamics coupled to a new state-following algorithm on CIS potential energy surfaces. Most clusters were found to completely dissociate and resulted in a single excited atomic state (90%), however, some trajectories formed bound, He*2 (3%), and a few yielded excited trimers (<0.5%). Comparisons were made with available experimental information on much larger clusters. Various applications of this state following algorithm are also presented. In addition to AIMD, these include excited-state geometry optimization and minimal energy path finding via the growing string method. When using state following we demonstrate that more physical results can be obtained with AIMD calculations. Also, the optimized geometries of three excited states of cytosine, two of which were not found without state following, and the minimal energy path between the lowest two singlet excited states of protonated formaldimine are offered as example applications. Finally, to address large clusters, a local variation of CIS was developed. This method exploits the properties of absolutely localized molecular orbitals (ALMOs) to limit the total number of excitations to scaling only linearly with cluster size, which results in formal scaling with the third power of the system size. The derivation of the equations and design of the algorithm are discussed in detail, and computational timings as well as a pilot application to the size dependence of the helium cluster spectrum are presented.

  11. Uranium hydrogeochemical and stream sediment reconnaissance data release for the Lewistown NTMS Quadrangle, Montana, including concentrations of forty-two additional elements

    SciTech Connect

    Shannon, S.S. Jr.

    1980-08-01

    Totals of 758 water and 1170 sediment samples were collected from 1649 locations in the Levistown quadrangle. Water samples were collected at streams, springs, wells, ponds, and marshes; sediment samples were obtained from streams, springs, and ponds. Histograms and statistical data for uranium concentrations in water and sediment samples and thorium concentrations in sediment samples are given. All samples were collected at the nominal reconnaissance density of one sample location per 10 km/sup 2/. Elemental concentration, field measurement, weather, geologic, and geographic data for each sample location are listed for waters and for sediments. Uranium to thorium (U/Th) ratios for sediment samples are included. Water samples were initially analyzed for uranium by fluorometry. All water samples containing more than 40 ppB U were reanalyzed by delayed-neutron counting. Sediments were analyzed for U and Th as well as Al, Sb, Ba, Be, Bi, Cd, Ca, Ce, Cs, Cl, Cr, Co, Cu, Dy, Eu, Au, Hf, Fe, La, Pb, Li, Lu, Mg, Mn, Ni, Nb, K, Rb, Sa, Sc, Ag, Na, Sr, Ta, Tb, Sn, Ti, W, V, Yb, and Zn. All sediments were analyzed for U by delayed neutron counting. Other elemental concentrations in sediments were determined by neutron activation analysis for 31 elements, by x-ray fluorescence for 9 elements, and by arc-source emission spectrography for 2 elements. Analytical results are reported as parts per million. Descriptions of procedures used for analysis of water and sediments samples as well as analytical precisions and detection limits are given.

  12. Manipulation and Characterization of a Novel Titanium Powder Precursor for Additive Manufacturing Applications

    NASA Astrophysics Data System (ADS)

    Sun, Y. Y.; Gulizia, S.; Oh, C. H.; Doblin, C.; Yang, Y. F.; Qian, M.

    2015-03-01

    Lowering the cost of feedstock powder has been a major issue for wider applications of additive manufacturing (AM) of titanium (Ti) and its alloys. A novel and inexpensive Ti sponge material was selected as a precursor and processed using a CSIRO proprietary powder manipulation technology (PMT). The manipulated powder was characterized in terms of the particle size distribution (PSD), roundness, flowability in the Hall Funnel flowmeter, static angle of repose (AOR), apparent density and tap density. In addition, a universal powder bed (UPB) system was used to characterize the manipulated powder behavior after raking. Two benchmark powders, virgin Arcam Ti-6Al-4V powder and used Arcam Ti-6Al-4V powder, were assessed for a comparison. PMT processing of the Ti powder precursor produced near spherically shaped Ti powder in the size range of 75-106 µm, which performed very similarly to the used Arcam powder in the UPB system. The CSIRO PMT offers a cost-effective manipulation process to produce Ti powder promising for AM applications, while the UPB system allows a quick assessment of the powder spreading behavior in AM processes.

  13. 34 CFR 611.2 - What management plan must be included in a Teacher Quality Enhancement Grants Program application?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What management plan must be included in a Teacher Quality Enhancement Grants Program application? 611.2 Section 611.2 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF...

  14. NASTRAN thermal analyzer: Theory and application including a guide to modeling engineering problems, volume 1. [thermal analyzer manual

    NASA Technical Reports Server (NTRS)

    Lee, H. P.

    1977-01-01

    The NASTRAN Thermal Analyzer Manual describes the fundamental and theoretical treatment of the finite element method, with emphasis on the derivations of the constituent matrices of different elements and solution algorithms. Necessary information and data relating to the practical applications of engineering modeling are included.

  15. 34 CFR 611.2 - What management plan must be included in a Teacher Quality Enhancement Grants Program application?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false What management plan must be included in a Teacher Quality Enhancement Grants Program application? 611.2 Section 611.2 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF...

  16. 30 CFR 250.1726 - When must I submit an initial platform removal application and what must it include?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false When must I submit an initial platform removal application and what must it include? 250.1726 Section 250.1726 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL...

  17. 45 CFR 2516.400 - What must a State or Indian tribe include in an application for a grant?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... following: (a) A three-year strategic plan for promoting service-learning through programs under this part, or a revision of a previously approved three-year strategic plan. The application of a SEA must include a description of how the SEA will coordinate its service-learning plan with the State Plan...

  18. 45 CFR 2516.400 - What must a State or Indian tribe include in an application for a grant?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... following: (a) A three-year strategic plan for promoting service-learning through programs under this part, or a revision of a previously approved three-year strategic plan. The application of a SEA must include a description of how the SEA will coordinate its service-learning plan with the State Plan...

  19. 45 CFR 2516.400 - What must a State or Indian tribe include in an application for a grant?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... following: (a) A three-year strategic plan for promoting service-learning through programs under this part, or a revision of a previously approved three-year strategic plan. The application of a SEA must include a description of how the SEA will coordinate its service-learning plan with the State Plan...

  20. 45 CFR 2516.400 - What must a State or Indian tribe include in an application for a grant?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... following: (a) A three-year strategic plan for promoting service-learning through programs under this part, or a revision of a previously approved three-year strategic plan. The application of a SEA must include a description of how the SEA will coordinate its service-learning plan with the State Plan...

  1. 45 CFR 2516.400 - What must a State or Indian tribe include in an application for a grant?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... following: (a) A three-year strategic plan for promoting service-learning through programs under this part, or a revision of a previously approved three-year strategic plan. The application of a SEA must include a description of how the SEA will coordinate its service-learning plan with the State Plan...

  2. 45 CFR 2517.410 - What must a qualified organization include in an application for a grant or a subgrant?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false What must a qualified organization include in an application for a grant or a subgrant? 2517.410 Section 2517.410 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE COMMUNITY-BASED...

  3. 45 CFR 2517.410 - What must a qualified organization include in an application for a grant or a subgrant?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false What must a qualified organization include in an application for a grant or a subgrant? 2517.410 Section 2517.410 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE COMMUNITY-BASED...

  4. 34 CFR 611.2 - What management plan must be included in a Teacher Quality Enhancement Grants Program application?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the proposed multiyear project, timeline, and budget information required by 34 CFR 75.112 and 75.117... 34 Education 3 2012-07-01 2012-07-01 false What management plan must be included in a Teacher Quality Enhancement Grants Program application? 611.2 Section 611.2 Education Regulations of the...

  5. 34 CFR 611.2 - What management plan must be included in a Teacher Quality Enhancement Grants Program application?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the proposed multiyear project, timeline, and budget information required by 34 CFR 75.112 and 75.117... 34 Education 3 2014-07-01 2014-07-01 false What management plan must be included in a Teacher Quality Enhancement Grants Program application? 611.2 Section 611.2 Education Regulations of the...

  6. 34 CFR 611.2 - What management plan must be included in a Teacher Quality Enhancement Grants Program application?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the proposed multiyear project, timeline, and budget information required by 34 CFR 75.112 and 75.117... 34 Education 3 2013-07-01 2013-07-01 false What management plan must be included in a Teacher Quality Enhancement Grants Program application? 611.2 Section 611.2 Education Regulations of the...

  7. Application of Tapping-Mode Scanning Probe Electrospray Ionization to Mass Spectrometry Imaging of Additives in Polymer Films

    PubMed Central

    Shimazu, Ryo; Yamoto, Yoshinari; Kosaka, Tomoya; Kawasaki, Hideya; Arakawa, Ryuichi

    2014-01-01

    We report the application of tapping-mode scanning probe electrospray ionization (t-SPESI) to mass spectrometry imaging of industrial materials. The t-SPESI parameters including tapping solvent composition, solvent flow rate, number of tapping at each spot, and step-size were optimized using a quadrupole mass spectrometer to improve mass spectrometry (MS) imaging of thin-layer chromatography (TLC) and additives in polymer films. Spatial resolution of approximately 100 μm was achieved by t-SPESI imaging mass spectrometry using a fused-silica capillary (50 μm i.d., 150 μm o.d.) with the flow rate set at 0.2 μL/min. This allowed us to obtain discriminable MS imaging profiles of three dyes separated by TLC and the additive stripe pattern of a PMMA model film depleted by UV irradiation. PMID:26819894

  8. Additional requirements for leak-before-break application to primary coolant piping in Belgium

    SciTech Connect

    Roussel, G.

    1997-04-01

    Leak-Before-Break (LBB) technology has not been applied in the first design of the seven Pressurized Water Reactors the Belgian utility is currently operating. The design basis of these plants required to consider the dynamic effects associated with the ruptures to be postulated in the high energy piping. The application of the LBB technology to the existing plants has been recently approved by the Belgian Safety Authorities but with a limitation to the primary coolant loop. LBB analysis has been initiated for the Doel 3 and Tihange 2 plants to allow the withdrawal of some of the reactor coolant pump snubbers at both plants and not reinstall some of the restraints after steam generator replacement at Doel 3. LBB analysis was also found beneficial to demonstrate the acceptability of the primary components and piping to the new conditions resulting from power uprating and stretch-out operation. LBB analysis has been subsequently performed on the primary coolant loop of the Tihange I plant and is currently being performed for the Doel 4 plant. Application of the LBB to the primary coolant loop is based in Belgium on the U.S. Nuclear Regulatory Commission requirements. However the Belgian Safety Authorities required some additional analyses and put some restrictions on the benefits of the LBB analysis to maintain the global safety of the plant at a sufficient level. This paper develops the main steps of the safety evaluation performed by the Belgian Safety Authorities for accepting the application of the LBB technology to existing plants and summarizes the requirements asked for in addition to the U.S. Nuclear Regulatory Commission rules.

  9. Effects of Biochar Addition on CO2 and N2O Emissions following Fertilizer Application to a Cultivated Grassland Soil.

    PubMed

    Chen, Jingjing; Kim, Hyunjin; Yoo, Gayoung

    2015-01-01

    Carbon (C) sequestration potential of biochar should be considered together with emission of greenhouse gases when applied to soils. In this study, we investigated CO2 and N2O emissions following the application of rice husk biochars to cultivated grassland soils and related gas emissions tos oil C and nitrogen (N) dynamics. Treatments included biochar addition (CHAR, NO CHAR) and amendment (COMPOST, UREA, NO FERT). The biochar application rate was 0.3% by weight. The temporal pattern of CO2 emissions differed according to biochar addition and amendments. CO2 emissions from the COMPOST soils were significantly higher than those from the UREA and NO FERT soils and less CO2 emission was observed when biochar and compost were applied together during the summer. Overall N2O emission was significantly influenced by the interaction between biochar and amendments. In UREA soil, biochar addition increased N2O emission by 49% compared to the control, while in the COMPOST and NO FERT soils, biochar did not have an effect on N2O emission. Two possible mechanisms were proposed to explain the higher N2O emissions upon biochar addition to UREA soil than other soils. Labile C in the biochar may have stimulated microbial N mineralization in the C-limited soil used in our study, resulting in an increase in N2O emission. Biochar may also have provided the soil with the ability to retain mineral N, leading to increased N2O emission. The overall results imply that biochar addition can increase C sequestration when applied together with compost, and might stimulate N2O emission when applied to soil amended with urea.

  10. Effects of Biochar Addition on CO2 and N2O Emissions following Fertilizer Application to a Cultivated Grassland Soil

    PubMed Central

    Chen, Jingjing; Kim, Hyunjin; Yoo, Gayoung

    2015-01-01

    Carbon (C) sequestration potential of biochar should be considered together with emission of greenhouse gases when applied to soils. In this study, we investigated CO2 and N2O emissions following the application of rice husk biochars to cultivated grassland soils and related gas emissions tos oil C and nitrogen (N) dynamics. Treatments included biochar addition (CHAR, NO CHAR) and amendment (COMPOST, UREA, NO FERT). The biochar application rate was 0.3% by weight. The temporal pattern of CO2 emissions differed according to biochar addition and amendments. CO2 emissions from the COMPOST soils were significantly higher than those from the UREA and NO FERT soils and less CO2 emission was observed when biochar and compost were applied together during the summer. Overall N2O emission was significantly influenced by the interaction between biochar and amendments. In UREA soil, biochar addition increased N2O emission by 49% compared to the control, while in the COMPOST and NO FERT soils, biochar did not have an effect on N2O emission. Two possible mechanisms were proposed to explain the higher N2O emissions upon biochar addition to UREA soil than other soils. Labile C in the biochar may have stimulated microbial N mineralization in the C-limited soil used in our study, resulting in an increase in N2O emission. Biochar may also have provided the soil with the ability to retain mineral N, leading to increased N2O emission. The overall results imply that biochar addition can increase C sequestration when applied together with compost, and might stimulate N2O emission when applied to soil amended with urea. PMID:26020941

  11. Effects of Biochar Addition on CO2 and N2O Emissions following Fertilizer Application to a Cultivated Grassland Soil.

    PubMed

    Chen, Jingjing; Kim, Hyunjin; Yoo, Gayoung

    2015-01-01

    Carbon (C) sequestration potential of biochar should be considered together with emission of greenhouse gases when applied to soils. In this study, we investigated CO2 and N2O emissions following the application of rice husk biochars to cultivated grassland soils and related gas emissions tos oil C and nitrogen (N) dynamics. Treatments included biochar addition (CHAR, NO CHAR) and amendment (COMPOST, UREA, NO FERT). The biochar application rate was 0.3% by weight. The temporal pattern of CO2 emissions differed according to biochar addition and amendments. CO2 emissions from the COMPOST soils were significantly higher than those from the UREA and NO FERT soils and less CO2 emission was observed when biochar and compost were applied together during the summer. Overall N2O emission was significantly influenced by the interaction between biochar and amendments. In UREA soil, biochar addition increased N2O emission by 49% compared to the control, while in the COMPOST and NO FERT soils, biochar did not have an effect on N2O emission. Two possible mechanisms were proposed to explain the higher N2O emissions upon biochar addition to UREA soil than other soils. Labile C in the biochar may have stimulated microbial N mineralization in the C-limited soil used in our study, resulting in an increase in N2O emission. Biochar may also have provided the soil with the ability to retain mineral N, leading to increased N2O emission. The overall results imply that biochar addition can increase C sequestration when applied together with compost, and might stimulate N2O emission when applied to soil amended with urea. PMID:26020941

  12. Optimization-based additive decomposition of weakly coercive problems with applications

    DOE PAGES

    Bochev, Pavel B.; Ridzal, Denis

    2016-01-27

    In this study, we present an abstract mathematical framework for an optimization-based additive decomposition of a large class of variational problems into a collection of concurrent subproblems. The framework replaces a given monolithic problem by an equivalent constrained optimization formulation in which the subproblems define the optimization constraints and the objective is to minimize the mismatch between their solutions. The significance of this reformulation stems from the fact that one can solve the resulting optimality system by an iterative process involving only solutions of the subproblems. Consequently, assuming that stable numerical methods and efficient solvers are available for every subproblem,more » our reformulation leads to robust and efficient numerical algorithms for a given monolithic problem by breaking it into subproblems that can be handled more easily. An application of the framework to the Oseen equations illustrates its potential.« less

  13. 12 CFR 516.220 - If OTS requests additional information to complete my application, how will it process my...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... complete my application, how will it process my application? 516.220 Section 516.220 Banks and Banking... Standard Treatment § 516.220 If OTS requests additional information to complete my application, how will it... your response. OTS will notify you that it has extended the period before the end of the initial...

  14. 12 CFR 116.220 - If the OCC requests additional information to complete my application, how will it process my...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... complete my application, how will it process my application? 116.220 Section 116.220 Banks and Banking... Treatment § 116.220 If the OCC requests additional information to complete my application, how will it... that it has extended the period before the end of the initial 15-day period and will briefly...

  15. 12 CFR 516.220 - If OTS requests additional information to complete my application, how will it process my...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... complete my application, how will it process my application? 516.220 Section 516.220 Banks and Banking... Standard Treatment § 516.220 If OTS requests additional information to complete my application, how will it... your response. OTS will notify you that it has extended the period before the end of the initial...

  16. Ionic Liquids as Novel Lubricants and Additives for Diesel Engine Applications

    SciTech Connect

    Qu, Jun; Blau, Peter Julian; Dai, Sheng; Luo, Huimin; Meyer III, Harry M

    2009-01-01

    The lubricating properties of two ionic liquids with the same anion but different cations, one ammonium IL [C8H17]3NH.Tf2N and one imidazolium IL C10mim.Tf2N, were evaluated both in neat form and as oil additives. Experiments were conducted using a standardized reciprocating sliding test using a segment of a Cr-plated diesel engine piston ring against a grey cast iron flat specimen with simulated honing marks as on the engine cylinder liner. The selected ionic liquids were benchmarked against conventional hydrocarbon oils. Substantial friction and wear reductions, up to 55% and 34%, respectively, were achieved for the neat ionic liquids compared to a fully-formulated 15W40 engine oil. Adding 5 vol% ILs into mineral oil has demonstrated significant improvement in the lubricity. One blend even outperformed the 15W40 engine oil with 9% lower friction and 34% less wear. Lubrication regime modeling, worn surface morphology examination, and surface chemical analysis were conducted to help understand the lubricating mechanisms for ionic liquids. Results suggest great potential for using ionic liquids as base lubricants or lubricant additives for diesel engine applications.

  17. Investigating calcium polyphosphate addition to a conventional calcium phosphate cement for bone-interfacing applications

    NASA Astrophysics Data System (ADS)

    Krausher, Jennifer Lynn

    Calcium phosphate cements (CPCs) are of great interest in bone regeneration applications because of their biocompatibility and osteoconductivity, and as delivery vehicles for therapeutics; however, delivery applications have been limited by adverse interactions between therapeutics and the cement setting reaction. Amorphous calcium polyphosphate (CPP) yields a biodegradable material with a demonstrated drug delivery capacity following appropriate processing. The incorporation of drug-loaded CPP into a CPC is under consideration as a method of minimizing adverse interactions and extending drug release. This thesis represents the first investigation into the effects of CPP addition on the properties, setting and antibiotic release profile of a conventional apatitic calcium phosphate cement. As-made, gelled and vancomycin-loaded CPP particulate were added to the powder component of a conventional dicalcium phosphate/tetracalcium phosphate CPC. The setting behaviour, set properties and microstructure of the resulting CPP-CPCs were evaluated with setting time testing (Gilmore needle method), pH testing, mechanical testing, SEM imaging, XRD and FTIR analysis. In vitro degradation and elution behaviour were evaluated by monitoring calcium release (atomic absorbance spectroscopy), mechanical strength and vancomycin release (UV-visual spectrophotometry). CPP addition was found to increase the setting time, reduce the mechanical strength and inhibit the conversion of the CPC starting powders to the set apatitic phase. The most likely mechanism for the observed effect of CPP addition was the adsorption of polyphosphate chains on the particle surfaces, which would inhibit the dissolution of the starting powders and the conversion of apatite precursor phases to apatite, leading to reduced mechanical properties. The detrimental effects of CPP were reduced by limiting the CPP fraction to less than a few weight per cent and increasing the size of the CPP particulate. CPP

  18. Study of mandible reconstruction using a fibula flap with application of additive manufacturing technology

    PubMed Central

    2014-01-01

    Background This study aimed to establish surgical guiding techniques for completing mandible lesion resection and reconstruction of the mandible defect area with fibula sections in one surgery by applying additive manufacturing technology, which can reduce the surgical duration and enhance the surgical accuracy and success rate. Methods A computer assisted mandible reconstruction planning (CAMRP) program was used to calculate the optimal cutting length and number of fibula pieces and design the fixtures for mandible cutting, registration, and arrangement of the fibula segments. The mandible cutting and registering fixtures were then generated using an additive manufacturing system. The CAMRP calculated the optimal fibula cutting length and number of segments based on the location and length of the defective portion of the mandible. The mandible cutting jig was generated according to the boundary surface of the lesion resection on the mandible STL model. The fibular cutting fixture was based on the length of each segment, and the registered fixture was used to quickly arrange the fibula pieces into the shape of the defect area. In this study, the mandibular lesion was reconstructed using registered fibular sections in one step, and the method is very easy to perform. Results and conclusion The application of additive manufacturing technology provided customized models and the cutting fixtures and registered fixtures, which can improve the efficiency of clinical application. This study showed that the cutting fixture helped to rapidly complete lesion resection and fibula cutting, and the registered fixture enabled arrangement of the fibula pieces and allowed completion of the mandible reconstruction in a timely manner. Our method can overcome the disadvantages of traditional surgery, which requires a long and different course of treatment and is liable to cause error. With the help of optimal cutting planning by the CAMRP and the 3D printed mandible resection jig and

  19. Fabrication of Thermoelectric Devices Using Additive-Subtractive Manufacturing Techniques: Application to Waste-Heat Energy Harvesting

    NASA Astrophysics Data System (ADS)

    Tewolde, Mahder

    Thermoelectric generators (TEGs) are solid-state devices that convert heat directly into electricity. They are well suited for waste-heat energy harvesting applications as opposed to primary energy generation. Commercially available thermoelectric modules are flat, inflexible and have limited sizes available. State-of-art manufacturing of TEG devices relies on assembling prefabricated parts with soldering, epoxy bonding, and mechanical clamping. Furthermore, efforts to incorporate them onto curved surfaces such as exhaust pipes, pump housings, steam lines, mixing containers, reaction chambers, etc. require custom-built heat exchangers. This is costly and labor-intensive, in addition to presenting challenges in terms of space, thermal coupling, added weight and long-term reliability. Additive manufacturing technologies are beginning to address many of these issues by reducing part count in complex designs and the elimination of sub-assembly requirements. This work investigates the feasibility of utilizing such novel manufacturing routes for improving the manufacturing process of thermoelectric devices. Much of the research in thermoelectricity is primarily focused on improving thermoelectric material properties by developing of novel materials or finding ways to improve existing ones. Secondary to material development is improving the manufacturing process of TEGs to provide significant cost benefits. To improve the device fabrication process, this work explores additive manufacturing technologies to provide an integrated and scalable approach for TE device manufacturing directly onto engineering component surfaces. Additive manufacturing techniques like thermal spray and ink-dispenser printing are developed with the aim of improving the manufacturing process of TEGs. Subtractive manufacturing techniques like laser micromachining are also studied in detail. This includes the laser processing parameters for cutting the thermal spray materials efficiently by

  20. 21 CFR 1311.150 - Additional requirements for internal application audits.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... interference with audit trail functions. (6) For application service providers, attempted or successful.... (b) The electronic prescription application must analyze the audit trail at least once every...

  1. Electric poling-assisted additive manufacturing process for PVDF polymer-based piezoelectric device applications

    NASA Astrophysics Data System (ADS)

    Lee, ChaBum; Tarbutton, Joshua A.

    2014-09-01

    This paper presents a new additive manufacturing (AM) process to directly and continuously print piezoelectric devices from polyvinylidene fluoride (PVDF) polymeric filament rods under a strong electric field. This process, called ‘electric poling-assisted additive manufacturing or EPAM, combines AM and electric poling processes and is able to fabricate free-form shape piezoelectric devices continuously. In this process, the PVDF polymer dipoles remain well-aligned and uniform over a large area in a single design, production and fabrication step. During EPAM process, molten PVDF polymer is simultaneously mechanically stresses in-situ by the leading nozzle and electrically poled by applying high electric field under high temperature. The EPAM system was constructed to directly print piezoelectric structures from PVDF polymeric filament while applying high electric field between nozzle tip and printing bed in AM machine. Piezoelectric devices were successfully fabricated using the EPAM process. The crystalline phase transitions that occurred from the process were identified by using the Fourier transform infrared spectroscope. The results indicate that devices printed under a strong electric field become piezoelectric during the EPAM process and that stronger electric fields result in greater piezoelectricity as marked by the electrical response and the formation of sharper peaks at the polar β crystalline wavenumber of the PVDF polymer. Performing this process in the absence of an electric field does not result in dipole alignment of PVDF polymer. The EPAM process is expected to lead to the widespread use of AM to fabricate a variety of piezoelectric PVDF polymer-based devices for sensing, actuation and energy harvesting applications with simple, low cost, single processing and fabrication step.

  2. The force-field derivation and application of explosive/additive interfaces

    NASA Astrophysics Data System (ADS)

    Long, Yao; Chen, Jun

    2016-10-01

    The inter-molecular force-field across RDX/(paraffin, fluoropolymer) interfaces are derived from first-principles calculated energies under the GGA+vdW functional. Based on the force-field, the polycrystal structures of mixture explosives are obtained, and a set of thermodynamic properties are calculated, including the elastic constants, thermal expansion coefficient, heat capacity, isothermal curve and the Hugoniot curve. The results are in good agreement with the available experiments, and provide a reasonable prediction about the properties of plastic bonded explosives. We find that the thermal expansion coefficient of a multi-component explosive is not only determined by the properties of the components, but is also affected by the thermal stress at the explosive/additive interfaces.

  3. Application and testing of additive manufacturing for mirrors and precision structures

    NASA Astrophysics Data System (ADS)

    Sweeney, Michael; Acreman, Martyn; Vettese, Tom; Myatt, Ray; Thompson, Mike

    2015-09-01

    Additive Manufacturing (aka AM, and 3-D printing) is widely touted in the media as the foundation for the next industrial revolution. Beneath the hype, AM does indeed offer profound advantages in lead-time, dramatically reduced consumption of expensive raw materials, while enabling new and innovative design forms that cannot be produced by other means. General Dynamics and their industry partners have begun to embrace this technology for mirrors and precision structures used in the aerospace, defense, and precision optical instrumentation industries. Aggressively lightweighted, open and closed back test mirror designs, 75-150 mm in size, were first produced by AM from several different materials. Subsequent optical finishing and test experiments have exceeded expectations for density, surface finish, dimensional stability and isotropy of thermal expansion on the optical scale of measurement. Materials currently under examination include aluminum, titanium, beryllium, aluminum beryllium, Inconel 625, stainless steel/bronze, and PEKK polymer.

  4. Logic For Qualification And Industrialisation Of Additive Layer Manufacturing Parts For Spatial Application

    NASA Astrophysics Data System (ADS)

    Brindeau, Aymeric; Lopes, Jean-Louis; Brivot, Frederic; Bourneaud, Florent; Desagulier, Christian

    2012-07-01

    ASTRIUM Space Transportation has been manufacturing composite equipments for satellite for 25 years. For this business, the development of Additive Layer Manufacturing (ALM) processes has been identified as a real opportunity to improve design and performances. For satellite equipments, ASTRIUM ST has chosen to investigate in the Electron Beam Melting process (patented EBM® process from Arcam AB company) for the manufacturing of Titanium parts, in collaboration with MECACHROME who has developed strong skills in this ALM process. This first development step has been achieved by introducing a titanium part realised by EBM on an equipment of Atlantic Bird 7 satellite launched in September 2011. The new step consists in the formal industrialisation of the EBM process for the procurement of titanium parts for satellite equipments. The present paper describes the logic retained for this industrialisation. It includes the technical requirements but also the verifications and inspections which have to be performed to guarantee that technical requirements are met.

  5. The effects of tantalum addition on the microtexture and mechanical behaviour of tungsten for ITER applications

    NASA Astrophysics Data System (ADS)

    Tejado, E.; Carvalho, P. A.; Munoz, A.; Dias, M.; Correia, J. B.; Mardolcar, U. V.; Pastor, J. Y.

    2015-12-01

    Tungsten (W) and its alloys are very promising materials for producing plasma-facing components (PFCs) in the fusion power reactors of the near future, even as a structural part in them. However, whereas the properties of pure tungsten are suitable for a PFC, its structural applications are still limited due to its low toughness, ductile to brittle transition temperature and recrystallization behaviour. Therefore, many efforts have been made to improve its performance by alloying tungsten with other elements. Hence, in this investigation, the thermo-mechanical performance of two new tungsten-tantalum materials has been evaluated. Materials with W-5wt.%Ta and W-15wt.%Ta were processed by mechanical alloying (MA) and later consolidation by hot isostatic pressing (HIP), with distinct settings for each composition. Thus, it was possible to determine the relationship between the microstructure and the addition of Ta with the macroscopic mechanical properties. These were measured by means of hardness, flexural strength and fracture toughness, in the temperature range of 300-1473 K. The microstructure and the fracture surfaces features of the tested materials were analysed by Field Emission Scanning Electron Microscopy (FESEM).

  6. 21 CFR 1311.150 - Additional requirements for internal application audits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Attempted unauthorized access to the electronic prescription application, or successful unauthorized access... any information or records required by this part, or successful unauthorized modification or...) Attempted or successful interference with audit trail functions. (6) For application service...

  7. 34 CFR 611.22 - What additional selection criteria are used for a pre-application that proposes teacher...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... EDUCATION TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM Partnership Grants Program § 611.22 What additional... 34 Education 3 2010-07-01 2010-07-01 false What additional selection criteria are used for a pre-application that proposes teacher recruitment activities? 611.22 Section 611.22 Education Regulations of...

  8. 34 CFR 611.22 - What additional selection criteria are used for a pre-application that proposes teacher...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... EDUCATION TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM Partnership Grants Program § 611.22 What additional... 34 Education 3 2011-07-01 2011-07-01 false What additional selection criteria are used for a pre-application that proposes teacher recruitment activities? 611.22 Section 611.22 Education Regulations of...

  9. 34 CFR 611.12 - What additional selection criteria are used for an application proposing teacher recruitment...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... EDUCATION TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM State Grants Program § 611.12 What additional selection... 34 Education 3 2011-07-01 2011-07-01 false What additional selection criteria are used for an application proposing teacher recruitment activities? 611.12 Section 611.12 Education Regulations of...

  10. 34 CFR 611.24 - What additional selection criteria are used for a full application that proposes teacher...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... EDUCATION TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM Partnership Grants Program § 611.24 What additional... 34 Education 3 2011-07-01 2011-07-01 false What additional selection criteria are used for a full application that proposes teacher recruitment activities? 611.24 Section 611.24 Education Regulations of...

  11. 20 CFR 641.210 - What services, in addition to the applicable core services, must SCSEP grantees provide through...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... core services, must SCSEP grantees provide through the One-Stop Delivery System? 641.210 Section 641... § 641.210 What services, in addition to the applicable core services, must SCSEP grantees provide through the One-Stop Delivery System? In addition to providing core services, SCSEP grantees must...

  12. Addition of Electrostatic Forces to EDEM with Applications to Triboelectrically Charged Particles

    NASA Technical Reports Server (NTRS)

    Hogue, Michael D.; Calle, Carlos; Curry, David

    2008-01-01

    Tribocharging of particles is common in many processes including fine powder handling and mixing, printer toner transport and dust extraction. In a lunar environment with its high vacuum and lack of water, electrostatic forces are an important factor to consider when designing and operating equipment. Dust mitigation and management is critical to safe and predictable performance of people and equipment. The extreme nature of lunar conditions makes it difficult and costly to carryout experiments on earth which are necessary to better understand how particles gather and transfer charge between each other and with equipment surfaces. DEM (Discrete Element Modeling) provides an excellent virtual laboratory for studying tribocharging of particles as well as for design of devices for dust mitigation and for other purposes related to handling and processing of lunar regolith. Theoretical and experimental work has been performed pursuant to incorporating screened Coulombic electrostatic forces into EDEM Tm, a commercial DEM software package. The DEM software is used to model the trajectories of large numbers of particles for industrial particulate handling and processing applications and can be coupled with other solvers and numerical models to calculate particle interaction with surrounding media and force fields. In this paper we will present overview of the theoretical calculations and experimental data and their comparison to the results of the DEM simulations. We will also discuss current plans to revise the DEM software with advanced electrodynamic and mechanical algorithms.

  13. The use of food consumption data in assessments of exposure to food chemicals including the application of probabilistic modelling.

    PubMed

    Lambe, Joyce

    2002-02-01

    Emphasis on public health and consumer protection, in combination with globalisation of the food market, has created a strong demand for exposure assessments of food chemicals. The food chemicals for which exposure assessments are required include food additives, pesticide residues, environmental contaminants, mycotoxins, novel food ingredients, packaging-material migrants, flavouring substances and nutrients. A wide range of methodologies exists for estimating exposure to food chemicals, and the method chosen for a particular exposure assessment is influenced by the nature of the chemical, the purpose of the assessment and the resources available. Sources of food consumption data currently used in exposure assessments range from food balance sheets to detailed food consumption surveys of individuals and duplicate-diet studies. The fitness-for-purpose of the data must be evaluated in the context of data quality and relevance to the assessment objective. Methods to combine the food consumption data with chemical concentration data may be deterministic or probabilistic. Deterministic methods estimate intakes of food chemicals that may occur in a population, but probabilistic methods provide the advantage of estimating the probability with which different levels of intake will occur. Probabilistic analysis permits the exposure assessor to model the variability (true heterogeneity) and uncertainty (lack of knowledge) that may exist in the exposure variables, including food consumption data, and thus to examine the full distribution of possible resulting exposures. Challenges for probabilistic modelling include the selection of appropriate modes of inputting food consumption data into the models. PMID:12002785

  14. The use of food consumption data in assessments of exposure to food chemicals including the application of probabilistic modelling.

    PubMed

    Lambe, Joyce

    2002-02-01

    Emphasis on public health and consumer protection, in combination with globalisation of the food market, has created a strong demand for exposure assessments of food chemicals. The food chemicals for which exposure assessments are required include food additives, pesticide residues, environmental contaminants, mycotoxins, novel food ingredients, packaging-material migrants, flavouring substances and nutrients. A wide range of methodologies exists for estimating exposure to food chemicals, and the method chosen for a particular exposure assessment is influenced by the nature of the chemical, the purpose of the assessment and the resources available. Sources of food consumption data currently used in exposure assessments range from food balance sheets to detailed food consumption surveys of individuals and duplicate-diet studies. The fitness-for-purpose of the data must be evaluated in the context of data quality and relevance to the assessment objective. Methods to combine the food consumption data with chemical concentration data may be deterministic or probabilistic. Deterministic methods estimate intakes of food chemicals that may occur in a population, but probabilistic methods provide the advantage of estimating the probability with which different levels of intake will occur. Probabilistic analysis permits the exposure assessor to model the variability (true heterogeneity) and uncertainty (lack of knowledge) that may exist in the exposure variables, including food consumption data, and thus to examine the full distribution of possible resulting exposures. Challenges for probabilistic modelling include the selection of appropriate modes of inputting food consumption data into the models.

  15. The addition of GTN to capsaicin cream reduces the discomfort associated with application of capsaicin alone. A volunteer study.

    PubMed

    McCleane, G J; McLaughlin, M

    1998-11-01

    In a double blind, placebo controlled trial of 40 volunteers, the burning discomfort associated with application of capsaicin cream (0.025%) was compared to placebo, GTN cream (1.33%) and to the combination of capsaicin cream (0.025%) plus GTN cream 1.33%. Median VAS for burning pain were 0 for the placebo, GTN and GTN + capsaicin groups and 3 for the capsaicin group after single application of each cream at daily intervals. This study demonstrates that after single application the addition of GTN to capsaicin significantly reduces the burning discomfort associated with application of capsaicin alone.

  16. 40 CFR 1045.225 - How do I amend my application for certification to include new or modified engines or change an FEL?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) We may ask for more test data or engineering evaluations. You must give us these within 30 days after... application for certification to include new or modified engines or change an FEL? Before we issue you a... application if any changes occur with respect to any information included in your application. (a) You...

  17. 24 CFR 570.466 - Additional application submission requirements for Pockets of Poverty-employment opportunities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... requirements for Pockets of Poverty-employment opportunities. 570.466 Section 570.466 Housing and Urban... application submission requirements for Pockets of Poverty—employment opportunities. Applicants for Action Grants under the Pockets of Poverty provision must describe the number and, to the extent possible,...

  18. 24 CFR 570.466 - Additional application submission requirements for Pockets of Poverty-employment opportunities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... requirements for Pockets of Poverty-employment opportunities. 570.466 Section 570.466 Housing and Urban... application submission requirements for Pockets of Poverty—employment opportunities. Applicants for Action Grants under the Pockets of Poverty provision must describe the number and, to the extent possible,...

  19. 24 CFR 570.466 - Additional application submission requirements for Pockets of Poverty-employment opportunities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... requirements for Pockets of Poverty-employment opportunities. 570.466 Section 570.466 Housing and Urban... application submission requirements for Pockets of Poverty—employment opportunities. Applicants for Action Grants under the Pockets of Poverty provision must describe the number and, to the extent possible,...

  20. 24 CFR 570.466 - Additional application submission requirements for Pockets of Poverty-employment opportunities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... requirements for Pockets of Poverty-employment opportunities. 570.466 Section 570.466 Housing and Urban... application submission requirements for Pockets of Poverty—employment opportunities. Applicants for Action Grants under the Pockets of Poverty provision must describe the number and, to the extent possible,...

  1. Possibilities of Application of Carbon-Fluorine Containing Additions in Submerged-Arc Welding

    NASA Astrophysics Data System (ADS)

    Kozyrev, N. A.; Kryukov, N. E.; Kryukov, R. E.; Igushev, V. F.; Kovalskii, I. I.

    2015-09-01

    The paper provides results of comparative analysis of the effect of carbonaceous components introduced into welding fluxes on molten metal - slag interaction. A positive influence of carbonaceous additives on gas content and mechanical properties of welds is demonstrated. Carbon and fluorine containing additives are emphasized to be promising for automatic submerged arc welding.

  2. Development of Constraint Force Equation Methodology for Application to Multi-Body Dynamics Including Launch Vehicle Stage Seperation

    NASA Technical Reports Server (NTRS)

    Pamadi, Bandu N.; Toniolo, Matthew D.; Tartabini, Paul V.; Roithmayr, Carlos M.; Albertson, Cindy W.; Karlgaard, Christopher D.

    2016-01-01

    The objective of this report is to develop and implement a physics based method for analysis and simulation of multi-body dynamics including launch vehicle stage separation. The constraint force equation (CFE) methodology discussed in this report provides such a framework for modeling constraint forces and moments acting at joints when the vehicles are still connected. Several stand-alone test cases involving various types of joints were developed to validate the CFE methodology. The results were compared with ADAMS(Registered Trademark) and Autolev, two different industry standard benchmark codes for multi-body dynamic analysis and simulations. However, these two codes are not designed for aerospace flight trajectory simulations. After this validation exercise, the CFE algorithm was implemented in Program to Optimize Simulated Trajectories II (POST2) to provide a capability to simulate end-to-end trajectories of launch vehicles including stage separation. The POST2/CFE methodology was applied to the STS-1 Space Shuttle solid rocket booster (SRB) separation and Hyper-X Research Vehicle (HXRV) separation from the Pegasus booster as a further test and validation for its application to launch vehicle stage separation problems. Finally, to demonstrate end-to-end simulation capability, POST2/CFE was applied to the ascent, orbit insertion, and booster return of a reusable two-stage-to-orbit (TSTO) vehicle concept. With these validation exercises, POST2/CFE software can be used for performing conceptual level end-to-end simulations, including launch vehicle stage separation, for problems similar to those discussed in this report.

  3. 10 CFR 431.174 - Additional requirements applicable to Voluntary Independent Certification Program participants.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Independent Certification Program participants. 431.174 Section 431.174 Energy DEPARTMENT OF ENERGY ENERGY... requirements applicable to Voluntary Independent Certification Program participants. (a) Description of Voluntary Independent Certification Program participant. For purposes of this subpart, a manufacturer...

  4. 34 CFR 385.45 - What additional application requirements apply to the training of individuals for rehabilitation...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... applicants for a grant or contract to provide training under any of the programs in 34 CFR parts 386 through... professionals to address the needs of individuals with disabilities from minority backgrounds. (b) All applicants for a grant under any of the programs in 34 CFR parts 386 through 390 and 396 shall include...

  5. 34 CFR 385.45 - What additional application requirements apply to the training of individuals for rehabilitation...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... applicants for a grant or contract to provide training under any of the programs in 34 CFR parts 386 through... applicants for a grant under any of the programs in 34 CFR parts 386 through 390 and 396 shall include a... training of individuals for rehabilitation careers? 385.45 Section 385.45 Education Regulations of...

  6. 34 CFR 385.45 - What additional application requirements apply to the training of individuals for rehabilitation...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... applicants for a grant or contract to provide training under any of the programs in 34 CFR parts 386 through... applicants for a grant under any of the programs in 34 CFR parts 386 through 390 and 396 shall include a... training of individuals for rehabilitation careers? 385.45 Section 385.45 Education Regulations of...

  7. 34 CFR 385.45 - What additional application requirements apply to the training of individuals for rehabilitation...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... applicants for a grant or contract to provide training under any of the programs in 34 CFR parts 386 through... applicants for a grant under any of the programs in 34 CFR parts 386 through 390 and 396 shall include a... training of individuals for rehabilitation careers? 385.45 Section 385.45 Education Regulations of...

  8. 34 CFR 385.45 - What additional application requirements apply to the training of individuals for rehabilitation...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... applicants for a grant or contract to provide training under any of the programs in 34 CFR parts 386 through... applicants for a grant under any of the programs in 34 CFR parts 386 through 390 and 396 shall include a... training of individuals for rehabilitation careers? 385.45 Section 385.45 Education Regulations of...

  9. On an Additive Semigraphoid Model for Statistical Networks With Application to Pathway Analysis

    PubMed Central

    Li, Bing; Chun, Hyonho; Zhao, Hongyu

    2014-01-01

    We introduce a nonparametric method for estimating non-gaussian graphical models based on a new statistical relation called additive conditional independence, which is a three-way relation among random vectors that resembles the logical structure of conditional independence. Additive conditional independence allows us to use one-dimensional kernel regardless of the dimension of the graph, which not only avoids the curse of dimensionality but also simplifies computation. It also gives rise to a parallel structure to the gaussian graphical model that replaces the precision matrix by an additive precision operator. The estimators derived from additive conditional independence cover the recently introduced nonparanormal graphical model as a special case, but outperform it when the gaussian copula assumption is violated. We compare the new method with existing ones by simulations and in genetic pathway analysis. PMID:26401064

  10. Electrodes for high-definition transcutaneous DC stimulation for applications in drug delivery and electrotherapy, including tDCS.

    PubMed

    Minhas, Preet; Bansal, Varun; Patel, Jinal; Ho, Johnson S; Diaz, Julian; Datta, Abhishek; Bikson, Marom

    2010-07-15

    Transcutaneous electrical stimulation is applied in a range of biomedical applications including transcranial direct current stimulation (tDCS). tDCS is a non-invasive procedure where a weak direct current (<2 mA) is applied across the scalp to modulate brain function. High-definition tDCS (HD-tDCS) is a technique used to increase the spatial focality of tDCS by passing current across the scalp using <12 mm diameter electrodes. The purpose of this study was to design and optimize "high-definition" electrode-gel parameters for electrode durability, skin safety and subjective pain. Anode and cathode electrode potential, temperature, pH and subjective sensation over time were assessed during application of 2 mA direct current, for up to 22 min on agar gel or subject forearms. A selection of five types of solid-conductors (Ag pellet, Ag/AgCl pellet, rubber pellet, Ag/AgCl ring and Ag/AgCl disc) and seven conductive gels (Signa, Spectra, Tensive, Redux, BioGel, Lectron and CCNY-4) were investigated. The Ag/AgCl ring in combination with CCNY-4 gel resulted in the most favorable outcomes. Under anode stimulations, electrode potential and temperature rises were generally observed in all electrode-gel combinations except for Ag/AgCl ring and disc electrodes. pH remained constant for all solid-conductors except for both Ag and rubber pellet electrodes with Signa and CCNY-4 gels. Sensation ratings were independent of stimulation polarity. Ag/AgCl ring electrodes were found to be the most comfortable followed by Ag, rubber and Ag/AgCl pellet electrodes across all gels.

  11. Effects of including surface depressions in the application of the Precipitation-Runoff Modeling System in the Upper Flint River Basin, Georgia

    USGS Publications Warehouse

    Viger, Roland J.; Hay, Lauren E.; Jones, John W.; Buell, Gary R.

    2010-01-01

    This report documents an extension of the Precipitation Runoff Modeling System that accounts for the effect of a large number of water-holding depressions in the land surface on the hydrologic response of a basin. Several techniques for developing the inputs needed by this extension also are presented. These techniques include the delineation of the surface depressions, the generation of volume estimates for the surface depressions, and the derivation of model parameters required to describe these surface depressions. This extension is valuable for applications in basins where surface depressions are too small or numerous to conveniently model as discrete spatial units, but where the aggregated storage capacity of these units is large enough to have a substantial effect on streamflow. In addition, this report documents several new model concepts that were evaluated in conjunction with the depression storage functionality, including: ?hydrologically effective? imperviousness, rates of hydraulic conductivity, and daily streamflow routing. All of these techniques are demonstrated as part of an application in the Upper Flint River Basin, Georgia. Simulated solar radiation, potential evapotranspiration, and water balances match observations well, with small errors for the first two simulated data in June and August because of differences in temperatures from the calibration and evaluation periods for those months. Daily runoff simulations show increasing accuracy with streamflow and a good fit overall. Including surface depression storage in the model has the effect of decreasing daily streamflow for all but the lowest flow values. The report discusses the choices and resultant effects involved in delineating and parameterizing these features. The remaining enhancements to the model and its application provide a more realistic description of basin geography and hydrology that serve to constrain the calibration process to more physically realistic parameter values.

  12. Irish National Food Ingredient Database: application for assessing patterns of additive usage in foods.

    PubMed

    Gilsenan, M B; Lambe, J; Gibney, M J

    2002-12-01

    Patterns of food additive usage in the Irish food supply and changes in patterns of usage between 1995-97 and 1998-99 were assessed by means of an Irish National Food Ingredient Database (INFID). Of the 300 additives permitted for use according to the European Union food additives Directives, some 54% were recorded in foods in INFID. Colours, emulsifiers and acids were the most frequently used additive categories, representing 18, 13 and 12% of the total additives used, respectively. Colours were most commonly recorded in sauces (n = 182 brands, 26% of sauces), emulsifiers were most commonly recorded in biscuits (n = 181 brands, 47% of biscuits) and acids were most commonly recorded in sauces (304 brands, 43% of sauces). Carotenes (E160a), Annatto (E160b), mono- and diglycerides of fatty acids (E471) and citric acid (E330) were the most commonly used colour, emulsifier and acid, respectively. All diet soft drinks (n = 37), low-fat spreads (n = 25) and liver pâtés (n = 10) recorded the use of at least one additive. When expressed in terms of the number of brands that contain additives, sauces (n = 522, 73% of sauces), biscuits (n = 323, 84% of biscuits) and preserves (n = 321, 85% of preserves) were ranked highest. For most categories of additive (n = 24), there appeared to be a minimal change in qualitative additive usage between 1995-97 and 1998-99. However, there was a significant increase in the frequency of use of emulsifiers (p < 0.001), acids (p < 0.01), sweeteners (p < 0.05) and acidity regulators (p < 0.05), and a significant decrease in the frequency of use of antioxidants (p < 0.05) during the period 1998-99 compared with 1995-97. Despite changes in additive usage patterns, it appeared that changes in the types of brands on sale between both periods were more apparent than actual changes in qualitative ingredient formulations across brands, as some 17% of brands that were on sale in 1995-97 were no longer on sale in 1998-99.

  13. Multiscale simulation process and application to additives in porous composite battery electrodes

    NASA Astrophysics Data System (ADS)

    Wieser, Christian; Prill, Torben; Schladitz, Katja

    2015-03-01

    Structure-resolving simulation of porous materials in electrochemical cells such as fuel cells and lithium ion batteries allows for correlating electrical performance with material morphology. In lithium ion batteries characteristic length scales of active material particles and additives range several orders of magnitude. Hence, providing a computational mesh resolving all length scales is not reasonably feasible and requires alternative approaches. In the work presented here a virtual process to simulate lithium ion batteries by bridging the scales is introduced. Representative lithium ion battery electrode coatings comprised of μm-scale graphite particles as active material and a nm-scale carbon/polymeric binder mixture as an additive are imaged with synchrotron radiation computed tomography (SR-CT) and sequential focused ion beam/scanning electron microscopy (FIB/SEM), respectively. Applying novel image processing methodologies for the FIB/SEM images, data sets are binarized to provide a computational grid for calculating the effective mass transport properties of the electrolyte phase in the nanoporous additive. Afterwards, the homogenized additive is virtually added to the micropores of the binarized SR-CT data set representing the active particle structure, and the resulting electrode structure is assembled to a virtual half-cell for electrochemical microheterogeneous simulation. Preliminary battery performance simulations indicate non-negligible impact of the consideration of the additive.

  14. Applications of the conjugate gradient FFT method in scattering and radiation including simulations with impedance boundary conditions

    NASA Technical Reports Server (NTRS)

    Barkeshli, Kasra; Volakis, John L.

    1991-01-01

    The theoretical and computational aspects related to the application of the Conjugate Gradient FFT (CGFFT) method in computational electromagnetics are examined. The advantages of applying the CGFFT method to a class of large scale scattering and radiation problems are outlined. The main advantages of the method stem from its iterative nature which eliminates a need to form the system matrix (thus reducing the computer memory allocation requirements) and guarantees convergence to the true solution in a finite number of steps. Results are presented for various radiators and scatterers including thin cylindrical dipole antennas, thin conductive and resistive strips and plates, as well as dielectric cylinders. Solutions of integral equations derived on the basis of generalized impedance boundary conditions (GIBC) are also examined. The boundary conditions can be used to replace the profile of a material coating by an impedance sheet or insert, thus, eliminating the need to introduce unknown polarization currents within the volume of the layer. A general full wave analysis of 2-D and 3-D rectangular grooves and cavities is presented which will also serve as a reference for future work.

  15. Applications of the conjugate gradient FFT method in scattering and radiation including simulations with impedance boundary conditions

    NASA Astrophysics Data System (ADS)

    Barkeshli, Kasra; Volakis, John L.

    1991-05-01

    The theoretical and computational aspects related to the application of the Conjugate Gradient FFT (CGFFT) method in computational electromagnetics are examined. The advantages of applying the CGFFT method to a class of large scale scattering and radiation problems are outlined. The main advantages of the method stem from its iterative nature which eliminates a need to form the system matrix (thus reducing the computer memory allocation requirements) and guarantees convergence to the true solution in a finite number of steps. Results are presented for various radiators and scatterers including thin cylindrical dipole antennas, thin conductive and resistive strips and plates, as well as dielectric cylinders. Solutions of integral equations derived on the basis of generalized impedance boundary conditions (GIBC) are also examined. The boundary conditions can be used to replace the profile of a material coating by an impedance sheet or insert, thus, eliminating the need to introduce unknown polarization currents within the volume of the layer. A general full wave analysis of 2-D and 3-D rectangular grooves and cavities is presented which will also serve as a reference for future work.

  16. Meta-code for systematic analysis of chemical addition (SACHA): application to fluorination of C70 and carbon nanostructure growth.

    PubMed

    Ewels, Christopher P; Lier, Gregory Van; Geerlings, Paul; Charlier, Jean-Christophe

    2007-01-01

    We present a new computer program able to systematically study chemical addition to and growth or evolution of carbon nanostructures. SACHA is a meta-code able to exploit a wide variety of pre-existing molecular structure codes, automating the otherwise onerous task of constructing, running, and analyzing the large number of input files that are required when exploring structural isomers and addition paths. By way of examples we consider fluorination of the fullerene cage C70 and carbon nanostructure growth through C2 addition. We discuss the possibilities for extension of this technique to rapidly and efficiently explore structural energy landscapes and application to other areas of chemical and materials research.

  17. 18 CFR 33.3 - Additional information requirements for applications involving horizontal competitive impacts.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... based on operational control criteria as deemed necessary, but the applicant must explain the reasons... result of the proposed transaction, a single corporate entity obtains ownership or control over the... internal to the merging entities' systems or interconnecting the systems with other control areas...

  18. 18 CFR 33.3 - Additional information requirements for applications involving horizontal competitive impacts.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... based on operational control criteria as deemed necessary, but the applicant must explain the reasons... result of the proposed transaction, a single corporate entity obtains ownership or control over the... internal to the merging entities' systems or interconnecting the systems with other control areas...

  19. 75 FR 2122 - Additional Guidance Regarding Application of Current Procedures for Testing Energy Consumption of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-14

    ...) standard HRF-1-1979 (HRF-1). See Appendix A1, section 2.2; 47 FR 34517 (Aug. 10, 1982). HRF-1 specifies... ensure the consistent application of DOE's current test procedure to refrigerator-freezers with French doors, bottom-mounted freezers, and through-the-door (TTD) ice service (French door TTD models)....

  20. Development and applications of a stochastic convective parameterization for a smooth transition to cloud resolving scales that includes aerosol interactions

    NASA Astrophysics Data System (ADS)

    Grell, Georg; Freitas, Saulo

    2013-04-01

    With the increasing availability of computing power many numerical weather prediction models now run at computational grids with resolution of dx < 10km, "gray scales" for convective parameterizations, where convective clouds may be resolved as well as unresolved. In addition Air Quality Research and Forecast (AQRF) models have continuously increasing complexity and can treat the interactions of aerosol and cloud microphysics. In this paper we will describe a new convective parameterization that allows for both, a smooth transition to cloud resolving scales as well as a parameterized interaction of aerosols with cloud microphysics (aerosol indirect effect). The parameterization also includes options for the transport of chemical constituents, wet deposition, and some aqueous phase chemistry. The parameterization is a modification of the Grell and Dvenyi (2002) scheme, and is used in version of the Weather Research and Forecast model (WRF and WRF-Chem), the Brazilian Regional Atmospheric Modeling system (B-RAMS) and the global Flow following finite volume Icosahedral Model (FIM and FIM-Chem).

  1. Parametrically Guided Generalized Additive Models with Application to Mergers and Acquisitions Data

    PubMed Central

    Fan, Jianqing; Maity, Arnab; Wang, Yihui; Wu, Yichao

    2012-01-01

    Generalized nonparametric additive models present a flexible way to evaluate the effects of several covariates on a general outcome of interest via a link function. In this modeling framework, one assumes that the effect of each of the covariates is nonparametric and additive. However, in practice, often there is prior information available about the shape of the regression functions, possibly from pilot studies or exploratory analysis. In this paper, we consider such situations and propose an estimation procedure where the prior information is used as a parametric guide to fit the additive model. Specifically, we first posit a parametric family for each of the regression functions using the prior information (parametric guides). After removing these parametric trends, we then estimate the remainder of the nonparametric functions using a nonparametric generalized additive model, and form the final estimates by adding back the parametric trend. We investigate the asymptotic properties of the estimates and show that when a good guide is chosen, the asymptotic variance of the estimates can be reduced significantly while keeping the asymptotic variance same as the unguided estimator. We observe the performance of our method via a simulation study and demonstrate our method by applying to a real data set on mergers and acquisitions. PMID:23645976

  2. 18 CFR 33.3 - Additional information requirements for applications involving horizontal competitive impacts.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Additional information... and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE... role that entry could play in mitigating adverse competitive effects of the transaction; (3)...

  3. 18 CFR 33.3 - Additional information requirements for applications involving horizontal competitive impacts.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Additional information... and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE... role that entry could play in mitigating adverse competitive effects of the transaction; (3)...

  4. 18 CFR 33.4 - Additional information requirements for applications involving vertical competitive impacts.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Additional information... and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE... competitive effects of the transaction. (ii) The potential for entry in the market and the role that...

  5. 18 CFR 33.4 - Additional information requirements for applications involving vertical competitive impacts.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Additional information... and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE... competitive effects of the transaction. (ii) The potential for entry in the market and the role that...

  6. 18 CFR 33.4 - Additional information requirements for applications involving vertical competitive impacts.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Additional information... and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE... competitive effects of the transaction. (ii) The potential for entry in the market and the role that...

  7. 14 CFR 119.36 - Additional certificate application requirements for commercial operators.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... public accounting firm, if any. Information submitted must be signed by an officer, owner, or partner of... existing and anticipated income producing contracts and estimated revenue per mile or hour of operation by... debt (explain); (iii) Additional working capital (explain); (iv) Operating losses other...

  8. 34 CFR 660.32 - What additional selection criteria does the Secretary use for an application for a research...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... use for an application for a research project, a survey, or a study? 660.32 Section 660.32 Education..., DEPARTMENT OF EDUCATION THE INTERNATIONAL RESEARCH AND STUDIES PROGRAM How Does the Secretary Make a Grant... project, a survey, or a study? In addition to the criteria referred to in § 660.31, the...

  9. 34 CFR 350.55 - What are the additional considerations for selecting Field-Initiated Project applications for...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., DEPARTMENT OF EDUCATION DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM How Does the... 34 Education 2 2013-07-01 2013-07-01 false What are the additional considerations for selecting Field-Initiated Project applications for funding? 350.55 Section 350.55 Education Regulations of...

  10. 34 CFR 350.55 - What are the additional considerations for selecting Field-Initiated Project applications for...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., DEPARTMENT OF EDUCATION DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM How Does the... 34 Education 2 2014-07-01 2013-07-01 true What are the additional considerations for selecting Field-Initiated Project applications for funding? 350.55 Section 350.55 Education Regulations of...

  11. 34 CFR 350.55 - What are the additional considerations for selecting Field-Initiated Project applications for...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., DEPARTMENT OF EDUCATION DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM How Does the... 34 Education 2 2011-07-01 2010-07-01 true What are the additional considerations for selecting Field-Initiated Project applications for funding? 350.55 Section 350.55 Education Regulations of...

  12. 34 CFR 350.55 - What are the additional considerations for selecting Field-Initiated Project applications for...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., DEPARTMENT OF EDUCATION DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM How Does the... 34 Education 2 2012-07-01 2012-07-01 false What are the additional considerations for selecting Field-Initiated Project applications for funding? 350.55 Section 350.55 Education Regulations of...

  13. 12 CFR 208.73 - What additional provisions are applicable to state member banks with financial subsidiaries?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... determining the bank's ratio of tangible equity to total assets under § 208.43(b)(5), the bank must deduct the... subsidiaries from the bank's tangible equity and total assets. (5) If the deduction from Tier 2 capital... 12 Banks and Banking 2 2010-01-01 2010-01-01 false What additional provisions are applicable...

  14. 34 CFR 660.33 - What additional selection criteria does the Secretary use for an application to develop...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., DEPARTMENT OF EDUCATION THE INTERNATIONAL RESEARCH AND STUDIES PROGRAM How Does the Secretary Make a Grant... 34 Education 3 2010-07-01 2010-07-01 false What additional selection criteria does the Secretary use for an application to develop specialized instructional materials? 660.33 Section 660.33...

  15. Harnessing reversible oxidative addition: application of diiodinated aromatic compounds in the carboiodination process.

    PubMed

    Petrone, David A; Lischka, Matthias; Lautens, Mark

    2013-09-27

    An I for an I: Conditions for the intramolecular carboiodination and the simultaneous convergent intramolecular carboiodination/intermolecular Heck reaction of various diiodoarenes were developed. The ability of the Pd(0)/QPhos catalyst/ligand combination to undergo reversible oxidative addition allows these reactions to proceed well, thus increasing both the appeal and utility of this class of substrates in site-selective cross-coupling reactions.

  16. 13 CFR 123.401 - What types of mitigation measures can your business include in an application for a pre-disaster...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false What types of mitigation measures can your business include in an application for a pre-disaster mitigation loan? 123.401 Section 123... Mitigation Loans § 123.401 What types of mitigation measures can your business include in an application...

  17. 13 CFR 123.401 - What types of mitigation measures can your business include in an application for a pre-disaster...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What types of mitigation measures can your business include in an application for a pre-disaster mitigation loan? 123.401 Section 123... Mitigation Loans § 123.401 What types of mitigation measures can your business include in an application...

  18. 13 CFR 123.401 - What types of mitigation measures can your business include in an application for a pre-disaster...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false What types of mitigation measures can your business include in an application for a pre-disaster mitigation loan? 123.401 Section 123... Mitigation Loans § 123.401 What types of mitigation measures can your business include in an application...

  19. 13 CFR 123.401 - What types of mitigation measures can your business include in an application for a pre-disaster...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false What types of mitigation measures can your business include in an application for a pre-disaster mitigation loan? 123.401 Section 123... Mitigation Loans § 123.401 What types of mitigation measures can your business include in an application...

  20. Sound propagation in narrow tubes including effects of viscothermal and turbulent damping with application to charge air coolers

    NASA Astrophysics Data System (ADS)

    Knutsson, Magnus; Åbom, Mats

    2009-02-01

    additionally calculated for corresponding circular cross-sections for comparison and discussion. The two-ports are thereafter combined with numerically obtained multi-ports, representing the connecting tanks, in order to obtain the transmission properties for the charged air when passing the complete CAC. An attractive formalism for representation of the multi-ports based on the admittance relationship between the ports is presented. From this the first linear frequency domain model for CACs, which includes a complete treatment of losses in the cooling tubes and 3D effects in the connecting tanks is extracted in the form of a two-port. The frequency dependent transmission loss is calculated and compared to the corresponding experimental data with good agreement.

  1. 32 CFR 728.74 - Applicants for appointment in the regular Navy or Marine Corps and reserve components, including...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Applicants for appointment in the regular Navy... NAVY PERSONNEL MEDICAL AND DENTAL CARE FOR ELIGIBLE PERSONS AT NAVY MEDICAL DEPARTMENT FACILITIES Other Persons § 728.74 Applicants for appointment in the regular Navy or Marine Corps and reserve...

  2. 32 CFR 728.74 - Applicants for appointment in the regular Navy or Marine Corps and reserve components, including...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 5 2014-07-01 2014-07-01 false Applicants for appointment in the regular Navy... NAVY PERSONNEL MEDICAL AND DENTAL CARE FOR ELIGIBLE PERSONS AT NAVY MEDICAL DEPARTMENT FACILITIES Other Persons § 728.74 Applicants for appointment in the regular Navy or Marine Corps and reserve...

  3. 45 CFR 2516.410 - What must a community-based entity include in an application for a grant?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... fiscal audits and program evaluations; (2) Prior to the placement of a participant, consult with the... (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE SCHOOL-BASED SERVICE-LEARNING PROGRAMS Application... description of the proposed program goals and activities. The application of a community-based entity...

  4. Designing valid and optimised standard addition calibrations: Application to the determination of anions in seawater.

    PubMed

    Rodrigues, Joana; da Silva, Ricardo J N Bettencourt; Camões, M Filomena G F C; Oliveira, Cristina M

    2015-09-01

    A strategy for designing valid standard addition calibrations and for optimising their uncertainty is presented. The design of calibrations involves the development of models of the sensitivity and precision of the instrumental signal, in a wide range of analyte concentration (or any other studied quantity), and the definition of sample dilution and standard addition procedures that allow fulfilling the assumptions of the linear unweighted regression model in, typically, a smaller range of standard addition calibrations. Calibrators are prepared by diluting the sample and adding analyte with negligible uncertainty to fit in a concentration range where signals are homoscedastic. The minimisation of the uncertainty is supported on detailed measurement uncertainty models function of the calibrators preparation procedure and of analytical instrumentation performance. The number of collected signals replicates is defined by balancing their impact on the estimated expanded uncertainty, the resources needed and the target (maximum) uncertainty for the intended use of measurements. The calibration design strategy was successfully applied to the determination of the mass concentration (mg L(-1)) of Cl(-), Br(-), NO3(-) and SO4(-2) in seawater by ion chromatography. A target expanded uncertainty of 20% was defined for the determination of Cl(-), NO3(-) and SO4(-2), or 40% for the determination of the smaller mass concentration of Br(-). The developed measurement model produced reliable predictions of the measurement uncertainty from approximate concentration of the analyte in the sample, before its accurate quantification, thus proving optimisation is effective. Predictions are more prone to the variability of the measurement uncertainty estimation if based on low number of calibrators signals. The reported relative expanded uncertainty ranged from 7.1% to 49%.

  5. Biomedical applications of polymers derived by reversible addition - fragmentation chain-transfer (RAFT).

    PubMed

    Fairbanks, Benjamin D; Gunatillake, Pathiraja A; Meagher, Laurence

    2015-08-30

    RAFT- mediated polymerization, providing control over polymer length and architecture as well as facilitating post polymerization modification of end groups, has been applied to virtually every facet of biomedical materials research. RAFT polymers have seen particularly extensive use in drug delivery research. Facile generation of functional and telechelic polymers permits straightforward conjugation to many therapeutic compounds while synthesis of amphiphilic block copolymers via RAFT allows for the generation of self-assembled structures capable of carrying therapeutic payloads. With the large and growing body of literature employing RAFT polymers as drug delivery aids and vehicles, concern over the potential toxicity of RAFT derived polymers has been raised. While literature exploring this complication is relatively limited, the emerging consensus may be summed up in three parts: toxicity of polymers generated with dithiobenzoate RAFT agents is observed at high concentrations but not with polymers generated with trithiocarbonate RAFT agents; even for polymers generated with dithiobenzoate RAFT agents, most reported applications call for concentrations well below the toxicity threshold; and RAFT end-groups may be easily removed via any of a variety of techniques that leave the polymer with no intrinsic toxicity attributable to the mechanism of polymerization. The low toxicity of RAFT-derived polymers and the ability to remove end groups via straightforward and scalable processes make RAFT technology a valuable tool for practically any application in which a polymer of defined molecular weight and architecture is desired.

  6. Toxicogenomics concepts and applications to study hepatic effects of food additives and chemicals

    SciTech Connect

    Stierum, Rob . E-mail: stierum@voeding.tno.nl; Heijne, Wilbert; Kienhuis, Anne; Ommen, Ben van; Groten, John

    2005-09-01

    Transcriptomics, proteomics and metabolomics are genomics technologies with great potential in toxicological sciences. Toxicogenomics involves the integration of conventional toxicological examinations with gene, protein or metabolite expression profiles. An overview together with selected examples of the possibilities of genomics in toxicology is given. The expectations raised by toxicogenomics are earlier and more sensitive detection of toxicity. Furthermore, toxicogenomics will provide a better understanding of the mechanism of toxicity and may facilitate the prediction of toxicity of unknown compounds. Mechanism-based markers of toxicity can be discovered and improved interspecies and in vitro-in vivo extrapolations will drive model developments in toxicology. Toxicological assessment of chemical mixtures will benefit from the new molecular biological tools. In our laboratory, toxicogenomics is predominantly applied for elucidation of mechanisms of action and discovery of novel pathway-supported mechanism-based markers of liver toxicity. In addition, we aim to integrate transcriptome, proteome and metabolome data, supported by bioinformatics to develop a systems biology approach for toxicology. Transcriptomics and proteomics studies on bromobenzene-mediated hepatotoxicity in the rat are discussed. Finally, an example is shown in which gene expression profiling together with conventional biochemistry led to the discovery of novel markers for the hepatic effects of the food additives butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole.

  7. Aging effects on fire-retardant additives in organic materials for nuclear-plant applications

    SciTech Connect

    Clough, R.L.

    1982-08-01

    Inhibiting fire is a major concern of nuclear safety. One of the most widely used commercial fire-retardant additives incorporated into cable insulation and other organic materials to reduce their flammability has been the halocarbon (usually a chlorinated hydrocarbon), typically in combination with antimony oxide. Such materials may be installed for the design lifetime of a nuclear plant; this report describes an investigation of the long-term aging behavior of these fire-retardant additives in polymeric materials. Extensive aging experiments on fire-retarded formulations of ethylene propylene rubber (EPR) and of chlorosulfonated polyethylene (CSPE) have been carried out, with chemical analysis of halogen and antimony content performed as a function of aging time and conditions. Oxygen index flammability measurements were also performed on selected samples. Significant fire-retardant losses (both chlorine (Cl) and antimony (Sb)) were found to occur in certain of the fire-retardant materials but not in others, depending on the molecular structure of the particular halogen-containing component. The data indicate that the loss of halogen- and antimony-based fire retardants appears to be insignificant under ambient conditions expected for nuclear plants.

  8. Oil additive and telomer applications of 4-esters of trimellitic anhydride

    SciTech Connect

    Puskas, I.; Fields, E.K.; Piasek, E.J.

    1981-08-01

    Three methods for the selective 4-esterification of trimellitic anhydride (TMA) briefly reviewed are: (1) reaction of the acid chloride derivative of TMA with alcohols or phenols in the presence of stoichiometric quantities of a tertiary nitrogen base, (2) reaction between the carboxyl group of TMA and an ester of a low-boiling organic acid via a trans-acidolysis mechanism, and (3) thermal reaction of TMA with alcohols. A large number of esters prepared by these methods were evaluated as potential rust inhibitors in lubricating oils, and some differences in rust prevention were noted for esters resulting from the different modes of preparation. However, the data were in agreement that rust-preventing properties increase with increasing chain length in the ester moiety, and esters with more than 20 carbons in the chain performed excellently. The synthesis and applications of 4-tert-butyl pertrimellitate anhydride are described. The structure of the compound was also documented. (BLM)

  9. 45 CFR 2517.400 - What must a State Commission or grantmaking entity include in an application for a grant?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-LEARNING PROGRAMS Application Contents § 2517.400 What must a State Commission or grantmaking entity... promoting service-learning through programs under this part. The plan must describe the types of...

  10. 45 CFR 2517.400 - What must a State Commission or grantmaking entity include in an application for a grant?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...-LEARNING PROGRAMS Application Contents § 2517.400 What must a State Commission or grantmaking entity... promoting service-learning through programs under this part. The plan must describe the types of...

  11. Identification and application of additional restriction fragment length polymorphisms at the human ornithine transcarbamylase locus.

    PubMed

    Fox, J E; Hack, A M; Fenton, W A; Rosenberg, L E

    1986-06-01

    Two additional restriction fragment length polymorphisms (RFLPs) have been identified at the human ornithine transcarbamylase (OTC) locus. Approximately 11% of women are heterozygous for an RFLP characterized by polymorphic bands at 3.7 and 3.6 kilobasepairs (kbp) observed after DNA digestion with TaqI. Twenty-nine percent of women are heterozygous for an RFLP characterized by polymorphic bands at 18.0 and 5.2 kbp observed after digestion with BamHI. Thus, in combination with the previously reported RFLPs identified using MspI, the X chromosomes in approximately 80% of women at risk for having a son with OTC deficiency are distinguishable by RFLPs at the OTC locus. Furthermore, we show that these RFLPs will be useful in families for prenatal diagnosis of OTC deficiency, carrier detection, and carrier exclusion.

  12. Processing of New Materials by Additive Manufacturing: Iron-Based Alloys Containing Silver for Biomedical Applications

    NASA Astrophysics Data System (ADS)

    Niendorf, Thomas; Brenne, Florian; Hoyer, Peter; Schwarze, Dieter; Schaper, Mirko; Grothe, Richard; Wiesener, Markus; Grundmeier, Guido; Maier, Hans Jürgen

    2015-07-01

    In the biomedical sector, production of bioresorbable implants remains challenging due to improper dissolution rates or deficient strength of many candidate alloys. Promising materials for overcoming the prevalent drawbacks are iron-based alloys containing silver. However, due to immiscibility of iron and silver these alloys cannot be manufactured based on conventional processing routes. In this study, iron-manganese-silver alloys were for the first time synthesized by means of additive manufacturing. Based on combined mechanical, microscopic, and electrochemical studies, it is shown that silver particles well distributed in the matrix can be obtained, leading to cathodic sites in the composite material. Eventually, this results in an increased dissolution rate of the alloy. Stress-strain curves showed that the incorporation of silver barely affects the mechanical properties.

  13. An additional simple denitrification bioreactor using packed gel envelopes applicable to industrial wastewater treatment.

    PubMed

    Morita, Masahiko; Uemoto, Hiroaki; Watanabe, Atsushi

    2007-08-15

    A simple denitrification bioreactor for nitrate-containing wastewater without organic compounds was developed. This bioreactor consisted of packed gel envelopes in a single tank. Each envelope comprised two plates of gels containing Paracoccus denitrificans cells with an internal space between the plates. As an electron donor for denitrification, ethanol was injected into the internal space and not directly into the wastewater. P. denitrificans cells in the gel reduced nitrate to nitrogen gas by using the injected ethanol. Nitrate-containing desulfurization wastewater derived from a coal-fired thermal power plant was continuously treated with 20 packed gel envelopes (size, 1,000 x 900 x 12 mm; surface area, 1.44 m(2)) in a reactor tank (volume 1.5 m(3)). When the total nitrogen concentration in the inflow was around 150 mg-N x L(-1), the envelopes removed approximately 60-80% of the total nitrogen, and the maximum nitrogen removal rate was 5.0 g-N x day(-1) per square meter of the gel surface. This value corresponded to the volumetric nitrogen removal performance of 0.109 kg-N x m(-3) x day(-1). In each envelope, a high utilization efficiency of the electron donor was attained, although more than the double amount of the electron donor was empirically injected in the present activated sludge system to achieve denitrification when compared with the theoretical value. The bioreactor using the envelopes would be extremely effective as an additional denitrification system because these envelopes can be easily installed in the vacant spaces of preinstalled water treatment systems, without requiring additional facilities for removing surplus ethanol and sludge. PMID:17252606

  14. The application of additive technologies in creation a medical simulator-trainer of the human head operating field

    NASA Astrophysics Data System (ADS)

    Kashapov, L. N.; Kashapov, N. F.; Kashapov, R. N.; Pashaev, B. Y.

    2016-06-01

    The aim of the work was to determine the possible application of additive manufacturing technology during the manufacturing process as close as possible to reality of medical simulator-trainers. In work were used some additive manufacturing technologies: selective laser sintering (SLS), fused deposition modeling (FDM), binder Jetting. As a result, a prototype of simulator-trainer of the human head operating field, which based on the CT real patient, was manufactured and conducted its tests. It was found that structure, which is obtained with the use of 3D-printers ProJet 160, most appropriate and closest to the real properties of the bone.

  15. Additive effect of combined application of magnesium and MK-801 on analgesic action of morphine.

    PubMed

    Bujalska-Zadrożny, Magdalena; Duda, Kamila

    2014-01-01

    As previously reported, magnesium ions (Mg(2+)) administered in relatively low doses markedly potentiated opioid analgesia in neuropathic pain, in which the effectiveness of opioids is limited. Considering that Mg(2+) behaves like an N-methyl-D-aspartate receptor antagonist, the effect of this ion on the analgesic action of morphine was compared with that of MK-801. Acute pain was evoked by mechanical or thermal stimuli, whereas neuropathic hyperalgesia was induced by streptozotocin (STZ) administration. Magnesium sulphate (40 mg/kg i.p.) or MK-801 (0.05 mg/kg s.c.) administered alone did not modify the nociceptive threshold to acute stimuli or the streptozotocin hyperalgesia but significantly augmented the analgesic action of morphine (5 mg/kg i.p.). Furthermore, if these drugs (i.e. magnesium sulphate and MK-801) were applied concomitantly, a clear additive effect on the analgesic action of morphine occurred in both models of pain. Possible explanations of these observations are discussed. PMID:24577345

  16. Mechanically tunable aspheric lenses via additive manufacture of hanging elastomeric droplets for microscopic applications

    NASA Astrophysics Data System (ADS)

    Fuh, Yiin-Kuen; Chen, Pin-Wen; Lai, Zheng-Hong

    2016-07-01

    Mechanically deformable lenses with dynamically tunable focal lengths have been developed in this work. The fabricated five types of aspheric polydimethylsiloxane (PDMS) lenses presented here have an initial focal length of 7.0, 7.8, 9.0, 10.0 and 10.2 mm. Incorporating two modes of operation in biconvex and concave-convex configurations, the focal lengths can be tuned dynamically as 5.2-10.2, 5.5-9.9, 6.6-11.9, 6.1-13.5 and 6.6-13.5 mm respectively. Additive manufacturing was utilized to fabricate these five types of aspheric lenses (APLs) via sequential layering of PDMS materials. Complex structures with three-dimensional features and shorter focal lengths can be successfully produced by repeatedly depositing, inverting and curing controlled PDMS volume onto previously cured PDMS droplets. From our experiments, we empirically found a direct dependence of the focal length of the lenses with the amount (volume) of deposited PDMS droplets. This new mouldless, low-cost, and flexible lens fabrication method is able to transform an ordinary commercial smartphone camera into a low-cost portable microscope. A few microscopic features can be readily visualized, such as wrinkles of ladybird pupa and printed circuit board. The fabrication technique by successively applying hanging droplet and facile mechanical focal-length-tuning set-up can be easily adopted in the development of high-performance optical lenses.

  17. Testing Departure from Additivity in Tukey’s Model using Shrinkage: Application to a Longitudinal Setting

    PubMed Central

    Ko, Yi-An; Mukherjee, Bhramar; Smith, Jennifer A.; Park, Sung Kyun; Kardia, Sharon L.R.; Allison, Matthew A.; Vokonas, Pantel S.; Chen, Jinbo; Diez-Roux, Ana V.

    2014-01-01

    While there has been extensive research developing gene-environment interaction (GEI) methods in case-control studies, little attention has been given to sparse and efficient modeling of GEI in longitudinal studies. In a two-way table for GEI with rows and columns as categorical variables, a conventional saturated interaction model involves estimation of a specific parameter for each cell, with constraints ensuring identifiability. The estimates are unbiased but are potentially inefficient because the number of parameters to be estimated can grow quickly with increasing categories of row/column factors. On the other hand, Tukey’s one degree of freedom (df) model for non-additivity treats the interaction term as a scaled product of row and column main effects. Due to the parsimonious form of interaction, the interaction estimate leads to enhanced efficiency and the corresponding test could lead to increased power. Unfortunately, Tukey’s model gives biased estimates and low power if the model is misspecified. When screening multiple GEIs where each genetic and environmental marker may exhibit a distinct interaction pattern, a robust estimator for interaction is important for GEI detection. We propose a shrinkage estimator for interaction effects that combines estimates from both Tukey’s and saturated interaction models and use the corresponding Wald test for testing interaction in a longitudinal setting. The proposed estimator is robust to misspecification of interaction structure. We illustrate the proposed methods using two longitudinal studies — the Normative Aging Study and the Multi-Ethnic Study of Atherosclerosis. PMID:25112650

  18. Molecular Imprinting of Silica Nanoparticle Surfaces via Reversible Addition-Fragmentation Polymerization for Optical Biosensing Applications

    NASA Astrophysics Data System (ADS)

    Oluz, Zehra; Nayab, Sana; Kursun, Talya Tugana; Caykara, Tuncer; Yameen, Basit; Duran, Hatice

    Azo initiator modified surface of silica nanoparticles were coated via reversible addition-fragmentation polymerization (RAFT) of methacrylic acid and ethylene glycol dimethacrylate using 2-phenylprop 2-yl dithobenzoate as chain transfer agent. Using L-phenylalanine anilide as template during polymerization led molecularly imprinted nanoparticles. RAFT polymerization offers an efficient control of grafting process, while molecularly imprinted polymers shows enhanced capacity as sensor. L-phenylalanine anilide imprinted silica particles were characterized by X-Ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM). Performances of the particles were followed by surface plasmon resonance spectroscopy (SPR) after coating the final product on gold deposited glass substrate against four different analogous of analyte molecules: D-henylalanine anilide, L-tyrosine, L-tryptophan and L-phenylalanine. Characterizations indicated that silica particles coated with polymer layer do contain binding sites for L-phenylalanine anilide, and are highly selective for the molecule of interest. This project was supported by TUBITAK (Project No:112M804).

  19. Phosphorus applications improved the soil microbial responses under nitrogen additions in Chinese fir plantations of subtropical China

    NASA Astrophysics Data System (ADS)

    Zhang, Xinyu; Li, Dandan; Yang, Yang; Tang, Yuqian; Wang, Huimin; Chen, Fusheng; Sun, Xiaomin

    2016-04-01

    Nitrogen (N) deposition and low soil phosphorus (P) content aggravate the P limitation in subtropical forest soils. However, the responses of soil microbial communities, enzyme kinetics, and N cycling genes to P additions in subtropical plantations are still not clear. The hypothesis that P application can alleviate the limitation and improve the soil microbial properties was tested by long term field experiment in the Chinese fir plantations in subtropical China. Thirty 20m×20m plots were established in November 2011 and six different treatments were randomly distributed with five replicates. The treatments are control (CK, no N and P application), low N addition (N1: 50 kg N ha-1 yr-1), high N addition (N2: 100 kg N ha-1 yr-1), P addition (P: 50 kg P ha-1 yr-1), low N and P addition (N1P: 50 kg N ha-1 yr-1 and 50 kg P ha-1 yr-1) and high N and P addition (N2P: 100 kg N ha-1 yr-1 and 50 kg P ha-1 yr-1). A suite of responses of soil microorganism across four years (2012-2015) during three seasons (spring, summer and autumn) were measured. Following 4 years of N amendments, fertilized soils were more acidic and had lower soil microbial biomass carbon contents than CK. However, P alleviated the soil acidification and increased the soil microbial biomass carbon contents. Increases in microbial PLFA biomarkers and exoenzyme kinetics in N fertilized plots were observed in the initial year (2013) but reduced since then (2014 and 2015). Whereas P amendments increased the soil PLFA biomarkers and exoenzyme kinetics through the four years except that the acid phosphatase activities declined after 3 years applications. P applications enhanced the soil N cycling by increases the abundances of nitrifiers (ammonia-oxidizing archea) and denitrifiers (nos Z, norG, and nirK). The bacterial and fungal residue carbons (calculated by amino sugar indicators) were higher under NP fertilizations than the other treatments. Our results suggest that P application could improve the soil

  20. From lab to industrial: PZT nanoparticles synthesis and process control for application in additive manufacturing

    NASA Astrophysics Data System (ADS)

    Huang, Hsien-Lin

    Lead Zirconate Titanate (PZT) nanoparticles hold many promising current and future applications, such as PZT ink for 3-D printing or seeds for PZT thick films. One common method is hydrothermal growth, in which temperature, duration time, or mineralizer concentrations are optimized to produce PZT nanoparticles with desired morphology, controlled size and size distribution. A modified hydrothermal process is used to fabricate PZT nanoparticles. The novelty is to employ a high ramping rate (e.g., 20 deg C/min) to generate abrupt supersaturation so as to promote burst nucleation of PZT nanoparticles as well as a fast cooling rate (e.g., 5 deg C/min) with a controlled termination of crystal growth. As a result, PZT nanoparticles with a size distribution ranging from 200 nm to 800 nm are obtained with cubic morphology and good crystallinity. The identification of nanoparticles is confirmed through use of X-ray diffractometer (XRD). XRD patterns are used to compare sample variations in their microstructures such as lattice parameter. A cubic morphology and particle size are also examined via SEM images. The hydrothermal process is further modified with excess lead (from 20% wt. to 80% wt.) to significantly reduce amorphous phase and agglomeration of the PZT nanoparticles. With a modified process, the particle size still remains within the 200 nm to 800 nm. Also, the crystal structures (microstructure) of the samples show little variations. Finally, a semi-continuous hydrothermal manufacturing process was developed to substantially reduce the fabrication time and maintained the same high quality as the nanoparticles prepared in an earlier stage. In this semi-continuous process, a furnace is maintained at the process temperature (200 deg C), whereas autoclaves containing PZT sol are placed in and out of the furnace to control the ramp-up and cooling rates. This setup eliminates an extremely time-consuming step of cooling down the furnace, thus saving tremendous amount of

  1. Development of magnetodielectric materials to be used in additive manufacturing processes for high-frequency applications

    NASA Astrophysics Data System (ADS)

    Parsons, Paul Emerson, II

    Electrical devices for very-high frequency (VHF, 0.03 -- 0.3 GHz) and ultra-high frequency (UHF, 0.3 -- 3.0 GHz) are commonly used for communications. However, the wavelengths, lambda, of these frequency bands correspond to lengths between 10 and 0.1 m, resulting in prohibitively large devices. Materials with an index of refraction, n, greater than 1 can be used to effectively shrink these devices by a factor of 1/ n. In this thesis, magnetodielectric materials (MDM), where n ≥1, have been made to be used in additive manufacturing processes with strict particle size requirements and were developed using various methods, such as polyol reduction and conventional ceramic solid state processing. These materials were characterized using x-ray diffraction (XRD), scanning and transmission electron microscopy (SEM and TEM), vibrating sample magnetometry (VSM), to determine their crystalline, physical, and direct current (DC) magnetization properties. The techniques used to synthesize the MDM yielded particles that were chemically similar, but had drastically different physical properties which heavily influences their high-frequency electromagnetic properties. These materials were then uniformly dispersed into a non-conducting medium, such as a low-electrical loss polymer or resin, and formed into composite samples with variable volumetric loading. These composite samples were measured using several techniques to characterize the frequency-dependent electromagnetic (EM) properties, such as relative permeability, relative permittivity, and their respective losses. Finite element method (FEM) simulations were performed using these MDM-composites to design a spiral antenna to be used at approximately 585 MHz.

  2. 45 CFR 2516.410 - What must a community-based entity include in an application for a grant?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... October 1, 2009, in accordance with 45 CFR 2540.200-207, as well as the nonduplication, nondisplacement... (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE SCHOOL-BASED SERVICE-LEARNING PROGRAMS Application... protect the rights of those employees; (3) Develop an age-appropriate learning component for...

  3. 45 CFR 2516.410 - What must a community-based entity include in an application for a grant?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... October 1, 2009, in accordance with 45 CFR 2540.200-207, as well as the nonduplication, nondisplacement... (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE SCHOOL-BASED SERVICE-LEARNING PROGRAMS Application... protect the rights of those employees; (3) Develop an age-appropriate learning component for...

  4. 40 CFR 1051.225 - How do I amend my application for certification to include new or modified vehicle configurations...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the requirements of this part. (c) We may ask for more test data or engineering evaluations. You must... specified in subparts B and H of this part. If you amend your application by submitting new test data to... may ask to lower the FEL for your engine family only if you have test data from production...

  5. Generalized net analyte signal standard addition as a novel method for simultaneous determination: application in spectrophotometric determination of some pesticides.

    PubMed

    Asadpour-Zeynali, Karim; Saeb, Elhameh; Vallipour, Javad; Bamorowat, Mehdi

    2014-01-01

    Simultaneous spectrophotometric determination of three neonicotinoid insecticides (acetamiprid, imidacloprid, and thiamethoxam) by a novel method named generalized net analyte signal standard addition method (GNASSAM) in some binary and ternary synthetic mixtures was investigated. For this purpose, standard addition was performed using a single standard solution consisting of a mixture of standards of all analytes. Savings in time and amount of used materials are some of the advantages of this method. All determinations showed appropriate applicability of this method with less than 5% error. This method may be applied for linearly dependent data in the presence of known interferents. The GNASSAM combines the advantages of both the generalized standard addition method and net analyte signal; therefore, it may be a proper alternative for some other multivariate methods. PMID:24672886

  6. 13 CFR 123.402 - Can your business include its relocation as a mitigation measure in an application for a pre...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... relocation as a mitigation measure in an application for a pre-disaster mitigation loan? 123.402 Section 123... Mitigation Loans § 123.402 Can your business include its relocation as a mitigation measure in an application for a pre-disaster mitigation loan? Yes, you may request a pre-disaster mitigation loan for...

  7. 13 CFR 123.402 - Can your business include its relocation as a mitigation measure in an application for a pre...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... relocation as a mitigation measure in an application for a pre-disaster mitigation loan? 123.402 Section 123... Mitigation Loans § 123.402 Can your business include its relocation as a mitigation measure in an application for a pre-disaster mitigation loan? Yes, you may request a pre-disaster mitigation loan for...

  8. 13 CFR 123.402 - Can your business include its relocation as a mitigation measure in an application for a pre...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... relocation as a mitigation measure in an application for a pre-disaster mitigation loan? 123.402 Section 123... Mitigation Loans § 123.402 Can your business include its relocation as a mitigation measure in an application for a pre-disaster mitigation loan? Yes, you may request a pre-disaster mitigation loan for...

  9. 13 CFR 123.402 - Can your business include its relocation as a mitigation measure in an application for a pre...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... relocation as a mitigation measure in an application for a pre-disaster mitigation loan? 123.402 Section 123... Mitigation Loans § 123.402 Can your business include its relocation as a mitigation measure in an application for a pre-disaster mitigation loan? Yes, you may request a pre-disaster mitigation loan for...

  10. Application of multivariate analysis to the effects of additives on chemical and sensory quality of stored coffee brew.

    PubMed

    Pérez-Martínez, Mónica; Sopelana, Patricia; de Peña, M Paz; Cid, Concepción

    2008-12-24

    The aim of this work was to obtain a black coffee brew to be consumed hot by extension of its shelf life, by addition of additives. Four pH-regulator agents (sodium and potassium carbonates and bicarbonates), one pH regulator and antioxidant (sodium citrate), three antioxidants [sodium ascorbate, ethylenediaminetetracetic acid (EDTA), and sodium sulfite], and lactoserum were tested by sensory analysis. Sodium carbonate and bicarbonate were selected for a study of the physicochemical (soluble and volatile compounds related to the sensory properties) and sensorial quality of coffee brew stored for 90 days at 4 degrees C. Although both additives extended the shelf life of the coffee brew up to 60 days, sodium carbonate was the chosen additive because it was the most useful in limiting the pH decrease and perception of sourness, which are some of the main factors involved in the rejection of stored coffee brews, and it better maintained the aroma and taste/flavor. Moreover, the application of multivariate analysis facilitated first the description of the global changes of the coffee brews with or without additives throughout the storage using principal component analysis and second the obtainment of a simple equation only with pH and caffeic acid parameters to discriminate the three types of coffee brews and simplify the analytical process, by means of the stepwise discriminant analysis.

  11. [Effects and mechanism of alkaline wastes application and zinc fertilizer addition on Cd bioavailability in contaminated soil].

    PubMed

    Liu, Zhao-Bing; Ji, Xiong-Hui; Tian, Fa-Xiang; Peng, Hua; Wu, Jia-Mei; Shi, Li-Hong

    2011-04-01

    The effects of paper mill sludge, red mud and zinc fertilizer addition on remediation of acid cadmium contaminated paddy soil were studied in a pot experiment, and their beneficial effects were verified in a field experiment, by using lime as comparison. The pot experiment results showed that a single application (2 g x kg(-1)) of lime, paper mill sludge or red mud increased soil pH significantly. Compared with no applying alkaline substances, the soil exchangeable Ca content was increased by 33.1%-76.0% at 7 days after applying alkaline substances and 31.0%-78.3% at 30 days after rice transplanting, respectively. The soil available Cd content was significantly decreased by 38.4%-45.0% at 7 days after the three alkaline substances applications, and was decreased by 37.4%-52.9% and 33.2%-38.7% at 30 days and 60 days after rice transplanting, respectively. The Cd content in rice root and brown rice was decreased by 24.0%-48.5% and 26.3%-44.7%, respectively. With equal applications of lime, paper mill sludge and red mud, the effects on increase of soil pH and decrease in Cd accumulation by rice was lime > red mud > paper mill sludge. Compared with a single application (2 g x kg(-1)) of paper mill sludge or red mud, Cd accumulation decreased significantly following the application of zinc fertilizer (0.2 g x kg(-1)) field experimental results were similar to the pot experiment that Cd accumulation apparently declined in the first and second crops (late rice and autumn rape) following the application of paper mill sludge, red mud and addition of zinc fertilizer. The Cd content in brown rice and rape seeds was decreased by 27.1-65.1% and 16.4%-41.6%, respectively, compared with no alkaline substances application. The Cd content in brown rice reached the National Hygienic Standard for Grains (GB 2715-2005). Therefore, combined application of paper mill sludge or red mud with zinc fertilizer was a feasible method to remediate acid cadmium contaminated paddy soil. Rice

  12. Application of wave mechanics theory to fluid dynamics problems: Boundary layer on a circular cylinder including turbulence

    NASA Technical Reports Server (NTRS)

    Krzywoblocki, M. Z. V.

    1974-01-01

    The application of the elements of quantum (wave) mechanics to some special problems in the field of macroscopic fluid dynamics is discussed. Emphasis is placed on the flow of a viscous, incompressible fluid around a circular cylinder. The following subjects are considered: (1) the flow of a nonviscous fluid around a circular cylinder, (2) the restrictions imposed the stream function by the number of dimensions of space, and (3) the flow past three dimensional bodies in a viscous fluid, particularly past a circular cylinder in the symmetrical case.

  13. Colombia Mi Pronostico Flood Application: Updating and Improving the Mi Pronostico Flood Web Application to Include an Assessment of Flood Risk

    NASA Technical Reports Server (NTRS)

    Rushley, Stephanie; Carter, Matthew; Chiou, Charles; Farmer, Richard; Haywood, Kevin; Pototzky, Anthony, Jr.; White, Adam; Winker, Daniel

    2014-01-01

    Colombia is a country with highly variable terrain, from the Andes Mountains to plains and coastal areas, many of these areas are prone to flooding disasters. To identify these risk areas NASA's Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) was used to construct a digital elevation model (DEM) for the study region. The preliminary risk assessment was applied to a pilot study area, the La Mosca River basin. Precipitation data from the National Aeronautics and Space Administration (NASA) Tropical Rainfall Measuring Mission (TRMM)'s near-real-time rainfall products as well as precipitation data from the Instituto de Hidrologia, Meteorologia y Estudios Ambientales (the Institute of Hydrology, Meteorology and Environmental Studies, IDEAM) and stations in the La Mosca River Basin were used to create rainfall distribution maps for the region. Using the precipitation data and the ASTER DEM, the web application, Mi Pronóstico, run by IDEAM, was updated to include an interactive map which currently allows users to search for a location and view the vulnerability and current weather and flooding conditions. The geospatial information was linked to an early warning system in Mi Pronóstico that can alert the public of flood warnings and identify locations of nearby shelters.

  14. Novel alginate-based nanocarriers as a strategy to include high concentrations of hydrophobic compounds in hydrogels for topical application

    NASA Astrophysics Data System (ADS)

    Nguyen, H. T. P.; Munnier, E.; Souce, M.; Perse, X.; David, S.; Bonnier, F.; Vial, F.; Yvergnaux, F.; Perrier, T.; Cohen-Jonathan, S.; Chourpa, I.

    2015-06-01

    The cutaneous penetration of hydrophobic active molecules is of foremost concern in the dermatology and cosmetic formulation fields. The poor solubility in water of those molecules limits their use in hydrophilic forms such as gels, which are favored by patients with chronic skin disease. The aim of this work is to design a novel nanocarrier of hydrophobic active molecules and to determine its potential as an ingredient of a topical form. The nanocarrier consists of an oily core surrounded by a protective shell of alginate, a natural polysaccharide isolated from brown algae. These calcium alginate-based nanocarriers (CaANCs) were prepared at room temperature and without the use of organic solvent by an accelerated nanoemulsification-polymer crosslinking method. The size (hydrodynamic diameter ˜200 nm) and surface charge (zeta potential ˜ - 30 mV) of the CaANCs are both compatible with their application on skin. CaANCs loaded with a fluorescent label were stable in model hydrophilic galenic forms under different storage conditions. Curcumin was encapsulated in CaANCs with an efficiency of ˜95%, fully retaining its antioxidant activity. The application of the curcumin-loaded CaANCs on excised human skin led to a significant accumulation of the active molecules in the upper layers of the skin, asserting the potential of these nanocarriers in active pharmaceutical and cosmetic ingredients topical delivery.

  15. NASTRAN thermal analyzer: Theory and application including a guide to modeling engineering problems, volume 2. [sample problem library guide

    NASA Technical Reports Server (NTRS)

    Jackson, C. E., Jr.

    1977-01-01

    A sample problem library containing 20 problems covering most facets of Nastran Thermal Analyzer modeling is presented. Areas discussed include radiative interchange, arbitrary nonlinear loads, transient temperature and steady-state structural plots, temperature-dependent conductivities, simulated multi-layer insulation, and constraint techniques. The use of the major control options and important DMAP alters is demonstrated.

  16. 20 CFR 666.220 - What information must be included in a State Board's application for an Incentive Grant?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PERFORMANCE ACCOUNTABILITY UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Incentives and Sanctions for State Performance § 666.220 What information must be included in... negotiated levels of performance for title I, the levels of performance under title II and the levels...

  17. 20 CFR 666.220 - What information must be included in a State Board's application for an Incentive Grant?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PERFORMANCE ACCOUNTABILITY UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Incentives and Sanctions for State Performance § 666.220 What information must be included in... negotiated levels of performance for title I, the levels of performance under title II and the levels...

  18. Development of a robust DNA damage model including persistent telomere-associated damage with application to secondary cancer risk assessment.

    PubMed

    Rastgou Talemi, Soheil; Kollarovic, Gabriel; Lapytsko, Anastasiya; Schaber, Jörg

    2015-01-01

    Mathematical modelling has been instrumental to understand kinetics of radiation-induced DNA damage repair and associated secondary cancer risk. The widely accepted two-lesion kinetic (TLK) model assumes two kinds of double strand breaks, simple and complex ones, with different repair rates. Recently, persistent DNA damage associated with telomeres was reported as a new kind of DNA damage. We therefore extended existing versions of the TLK model by new categories of DNA damage and re-evaluated those models using extensive data. We subjected different versions of the TLK model to a rigorous model discrimination approach. This enabled us to robustly select a best approximating parsimonious model that can both recapitulate and predict transient and persistent DNA damage after ionizing radiation. Models and data argue for i) nonlinear dose-damage relationships, and ii) negligible saturation of repair kinetics even for high doses. Additionally, we show that simulated radiation-induced persistent telomere-associated DNA damage foci (TAF) can be used to predict excess relative risk (ERR) of developing secondary leukemia after fractionated radiotherapy. We suggest that TAF may serve as an additional measure to predict cancer risk after radiotherapy using high dose rates. This may improve predicting risk-dose dependency of ionizing radiation especially for long-term therapies. PMID:26359627

  19. Development of a robust DNA damage model including persistent telomere-associated damage with application to secondary cancer risk assessment

    PubMed Central

    Rastgou Talemi, Soheil; Kollarovic, Gabriel; Lapytsko, Anastasiya; Schaber, Jörg

    2015-01-01

    Mathematical modelling has been instrumental to understand kinetics of radiation-induced DNA damage repair and associated secondary cancer risk. The widely accepted two-lesion kinetic (TLK) model assumes two kinds of double strand breaks, simple and complex ones, with different repair rates. Recently, persistent DNA damage associated with telomeres was reported as a new kind of DNA damage. We therefore extended existing versions of the TLK model by new categories of DNA damage and re-evaluated those models using extensive data. We subjected different versions of the TLK model to a rigorous model discrimination approach. This enabled us to robustly select a best approximating parsimonious model that can both recapitulate and predict transient and persistent DNA damage after ionizing radiation. Models and data argue for i) nonlinear dose-damage relationships, and ii) negligible saturation of repair kinetics even for high doses. Additionally, we show that simulated radiation-induced persistent telomere-associated DNA damage foci (TAF) can be used to predict excess relative risk (ERR) of developing secondary leukemia after fractionated radiotherapy. We suggest that TAF may serve as an additional measure to predict cancer risk after radiotherapy using high dose rates. This may improve predicting risk-dose dependency of ionizing radiation especially for long-term therapies. PMID:26359627

  20. 40 CFR 1045.225 - How do I amend my application for certification to include new or modified engines or change an FEL?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... certification to include new or modified engines or change an FEL? 1045.225 Section 1045.225 Protection of... application for certification to include new or modified engines or change an FEL? Before we issue you a... that may affect emissions any time during the engine's lifetime. (3) Modify an FEL for an engine...

  1. 40 CFR 1045.225 - How do I amend my application for certification to include new or modified engines or change an FEL?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... certification to include new or modified engines or change an FEL? 1045.225 Section 1045.225 Protection of... application for certification to include new or modified engines or change an FEL? Before we issue you a... that may affect emissions any time during the engine's lifetime. (3) Modify an FEL for an engine...

  2. 40 CFR 1045.225 - How do I amend my application for certification to include new or modified engines or change an FEL?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... certification to include new or modified engines or change an FEL? 1045.225 Section 1045.225 Protection of... application for certification to include new or modified engines or change an FEL? Before we issue you a... that may affect emissions any time during the engine's lifetime. (3) Modify an FEL for an engine...

  3. Non-mechanical optical path switching and its application to dual beam spectroscopy including gas filter correlation radiometry

    NASA Technical Reports Server (NTRS)

    Sachse, Glen W. (Inventor); Wang, Liang-Guo (Inventor)

    1992-01-01

    A non-mechanical optical switch is developed for alternately switching a monochromatic or quasi-monochromatic light beam along two optical paths. A polarizer polarizes light into a single, e.g., vertical component which is then rapidly modulated into vertical and horizontal components by a polarization modulator. A polarization beam splitter then reflects one of these components along one path and transmits the other along the second path. In the specific application of gas filter correlation radiometry, one path is directed through a vacuum cell and one path is directed through a gas correlation cell containing a desired gas. Reflecting mirrors cause these two paths to intersect at a second polarization beam splitter which reflects one component and transmits the other to recombine them into a polarization modulated beam which can be detected by an appropriate single sensor.

  4. An Algorithm for Real-Time Optimal Photocurrent Estimation Including Transient Detection for Resource-Constrained Imaging Applications

    NASA Astrophysics Data System (ADS)

    Zemcov, Michael; Crill, Brendan; Ryan, Matthew; Staniszewski, Zak

    2016-06-01

    Mega-pixel charge-integrating detectors are common in near-IR imaging applications. Optimal signal-to-noise ratio estimates of the photocurrents, which are particularly important in the low-signal regime, are produced by fitting linear models to sequential reads of the charge on the detector. Algorithms that solve this problem have a long history, but can be computationally intensive. Furthermore, the cosmic ray background is appreciable for these detectors in Earth orbit, particularly above the Earth’s magnetic poles and the South Atlantic Anomaly, and on-board reduction routines must be capable of flagging affected pixels. In this paper, we present an algorithm that generates optimal photocurrent estimates and flags random transient charge generation from cosmic rays, and is specifically designed to fit on a computationally restricted platform. We take as a case study the Spectro-Photometer for the History of the Universe, Epoch of Reionization, and Ices Explorer (SPHEREx), a NASA Small Explorer astrophysics experiment concept, and show that the algorithm can easily fit in the resource-constrained environment of such a restricted platform. Detailed simulations of the input astrophysical signals and detector array performance are used to characterize the fitting routines in the presence of complex noise properties and charge transients. We use both Hubble Space Telescope Wide Field Camera-3 and Wide-field Infrared Survey Explorer to develop an empirical understanding of the susceptibility of near-IR detectors in low earth orbit and build a model for realistic cosmic ray energy spectra and rates. We show that our algorithm generates an unbiased estimate of the true photocurrent that is identical to that from a standard line fitting package, and characterize the rate, energy, and timing of both detected and undetected transient events. This algorithm has significant potential for imaging with charge-integrating detectors in astrophysics, earth science, and remote

  5. Synthesis of Ferrocene Oxazoline N,O ligands and Their Application in Asymmetric Ethyl- and Phenylzinc Additions to Aldehydes.

    PubMed

    Nottingham, Chris; Benson, Robert; Müller-Bunz, Helge; Guiry, Patrick J

    2015-10-16

    The synthesis of a range of novel gem-disubstituted ferrocene-oxazoline ligands and their application in both the asymmetric ethyl- and phenylzinc additions to aldehydes is reported. These studies reveal that gem-disubstitution of i-Pr-containing ferrocene oxazoline ligands results in increased enantioselectivity compared to their unsubstituted counterparts. Utilizing zinc catalysis, these ligands provided a wide range of secondary alcohols in yields of up to 93% with ee's of up to >99%. An interesting crystal structure of a ferrocene oxide-lithium tetramer showing lithium-nitrogen coordination in the solid state is also presented.

  6. Studies and analyses of the management of scientific research and development, including implementation and application at NASA centers

    NASA Technical Reports Server (NTRS)

    Rubenstein, A. H.

    1975-01-01

    Summary results obtained through the Program of Research on the Management of Research and Development (POMRAD) were presented. The nature of the overall program and the specific projects undertaken were described. Statistical data is also given concerning the papers, publications, people, and major program areas associated with the program. The actual list of papers, names of doctoral and masters theses, and other details of the program are included as appendices.

  7. FUNDAMENTAL AREAS OF PHENOMENOLOGY (INCLUDING APPLICATIONS): Sprout Branching of Tumour Capillary Network Growth: Fractal Dimension and Multifractal Structure

    NASA Astrophysics Data System (ADS)

    Kou, Jian-Long; Lu, Hang-Jun; Wu, Feng-Min; Xu, You-Sheng

    2008-05-01

    A tumour vascular network, characterized as an irregularly stochastic growth, is different from the normal vascular network. We systematically analyse the dependence of the branching. It is found that anastomosis of tumour on time is according to a number of tumour images, and both the fractal dimensions and multifractal spectra of the tumours are obtained. In the cases studied, the fractal dimensions of the tumour vascular network increase with time and the multifractal spectrum not only rises entirely but also shifts right. In addition, the best drug delivery stage is discussed according to the difference of the singularity exponent δα(δα = αmax — αmin), which shows some change in the growth process of the tumour vascular network. A common underlying principle is obtained from our analysis along with previous results.

  8. Application of array CGH on archival formalin-fixed paraffin-embedded tissues including small numbers of microdissected cells.

    PubMed

    Johnson, Nicola A; Hamoudi, Rifat A; Ichimura, Koichi; Liu, Lu; Pearson, Danita M; Collins, V Peter; Du, Ming-Qing

    2006-09-01

    Array-based comparative genomic hybridisation (aCGH) has diverse applications in cancer gene discovery and translational research. Currently, aCGH is performed primarily using high molecular weight DNA samples and its application to formalin-fixed and paraffin-embedded (FFPE) tissues remains to be established. To explore how aCGH can be reliably applied to archival FFPE tissues and whether it is possible to apply aCGH to small numbers of cells microdissected from FFPE tissue sections, we have systematically performed aCGH on 15 pairs of matched frozen and FFPE astrocytic tumour tissues using a well-established in-house human 1 Mb BAC/PAC genomic array. By spiking tumour DNA with normal DNA, we demonstrated that at least 70% of tumour DNA was required for reliable aCGH analysis. Using aCGH data from frozen tissue as a reference, it was found that only FFPE astrocytic tumour tissues that supported PCR amplification of >300 bp DNA fragment provided high quality, reproducible aCGH data. The presence of necrosis in a tissue specimen had an adverse effect on the quality of aCGH, while fixation in formalin for up to 96 h of fresh tissue did not appear to affect the quality of the result. As little as 10-20 ng DNA from frozen or FFPE tissues could be readily used for aCGH analysis following whole genome amplification (WGA). Furthermore, as few as 2000 microdissected cells from haematoxylin-stained slides of archival FFPE tissues could be successfully used for aCGH investigations when WGA was used. By careful assessment of DNA integrity and review of histology, to exclude necrosis and select specimens with a high proportion of tumour cells, it is feasible to preselect archival FFPE tissues adequate for aCGH analysis. With the help of microdissection and WGA, it is also possible to apply aCGH to histologically defined lesions, such as carcinoma in situ.

  9. Mathematical multi-scale model of the cardiovascular system including mitral valve dynamics. Application to ischemic mitral insufficiency

    PubMed Central

    2011-01-01

    Background Valve dysfunction is a common cardiovascular pathology. Despite significant clinical research, there is little formal study of how valve dysfunction affects overall circulatory dynamics. Validated models would offer the ability to better understand these dynamics and thus optimize diagnosis, as well as surgical and other interventions. Methods A cardiovascular and circulatory system (CVS) model has already been validated in silico, and in several animal model studies. It accounts for valve dynamics using Heaviside functions to simulate a physiologically accurate "open on pressure, close on flow" law. However, it does not consider real-time valve opening dynamics and therefore does not fully capture valve dysfunction, particularly where the dysfunction involves partial closure. This research describes an updated version of this previous closed-loop CVS model that includes the progressive opening of the mitral valve, and is defined over the full cardiac cycle. Results Simulations of the cardiovascular system with healthy mitral valve are performed, and, the global hemodynamic behaviour is studied compared with previously validated results. The error between resulting pressure-volume (PV) loops of already validated CVS model and the new CVS model that includes the progressive opening of the mitral valve is assessed and remains within typical measurement error and variability. Simulations of ischemic mitral insufficiency are also performed. Pressure-Volume loops, transmitral flow evolution and mitral valve aperture area evolution follow reported measurements in shape, amplitude and trends. Conclusions The resulting cardiovascular system model including mitral valve dynamics provides a foundation for clinical validation and the study of valvular dysfunction in vivo. The overall models and results could readily be generalised to other cardiac valves. PMID:21942971

  10. A design assessment of multiwall, metallic stand-off, and RSI reusable thermal protection systems including space shuttle application

    NASA Technical Reports Server (NTRS)

    Jackson, L. R.; Dixon, S. C.

    1980-01-01

    The design and assessment of reusable surface insulation (RSI), metallic stand off and multiwall thermal protection systems (TPS) is discussed. Multiwall TPS is described in some detail, and analyses useful for design of multiwall are included. Results indicate that multiwall has the potential to satisfy the TPS design goals better than the other systems. The total mass of the stand-off TPS and of the metallic systems require less primary structure mass than the RSI system, since the nonbuckling skin criteria required for RSI may be removed. Continued development of multiwall TPS is required to verify its potential and to provide the necessary data base for design.

  11. Continuous-flow microfluidic printing of proteins for array-based applications including surface plasmon resonance imaging.

    PubMed

    Natarajan, Sriram; Katsamba, Phini S; Miles, Adam; Eckman, Josh; Papalia, Giuseppe A; Rich, Rebecca L; Gale, Bruce K; Myszka, David G

    2008-02-01

    Arraying proteins is often more challenging than creating oligonucleotide arrays. Protein concentration and purity can severely limit the capacity of spots created by traditional pin and ink jet printing techniques. To improve protein printing methods, we have developed a three-dimensional microfluidic system to deposit protein samples within discrete spots (250-microm squares) on a target surface. Our current technology produces a 48-spot array within a 0.5 x 1 cm target area. A chief advantage of this method is that samples may be introduced in continuous flow, which makes it possible to expose each spot to a larger volume of sample than would be possible with standard printing methods. Using Biacore Flexchip (Biacore AB) surface plasmon resonance array-based biosensor as a chip reader, we demonstrate that the microfluidic printer is capable of spotting proteins that are dilute (<0.1 microg/ml) and contain high concentrations of contaminating protein (>10,000-fold molar excess). We also show that the spots created by the microfluidic printer are more uniform and have better-defined borders than what can be achieved with pin printing. The ability to readily print proteins using continuous flow will help expand the application of protein arrays.

  12. Specific applications of capillary electrochromatography to biopolymers, including proteins, nucleic acids, peptide mapping, antibodies, and so forth.

    PubMed

    Krull, I S; Sebag, A; Stevenson, R

    2000-07-28

    Separation of biopolymers is an obvious application of capillary electrochromatography (CEC) technology, since speed and resolution should increase significantly over high-performance liquid chromatography (HPLC). All too often, HPLC chromatograms of polymers show poorly resolved envelopes of overlapping peaks from oligomers. The practical limitation of column length and pressure drop has hindered development of high resolution separations of many polymers in HPLC. However, this generally applies only to packed beds of small particles, and not to continuous (or monolithic) beds, as introduced by Hjerten et al. [S. Hjerten, Ind. Eng. Chem. Res. 38 (1999) 1205; S. Hjerten, C. Ericson, Y.-M. Li, R. Zhang, Biomed. Chromatogr. 12 (1998) 120; C. Ericson, S. Hjerten, Anal. Chem. 71 (1999) 1621; J.-L. Liao, N. Chen, C. Ericson, S. Hjerten, Anal. Chem. 68 (1996) 3468; S. Hjerten, A. Vegvari, T. Srichaiyo, H.-X. Zhang, C. Ericson, D. Eaker, J. Capillary. Elec. 5 (1998) 13; C. Ericson, J.-L. Liao, K. Nakazato, S. Hjerten, J. Chromatogr. A 767 (1997) 33; S. Hjerten, D. Eaker, K. Elenbring, C. Ericson, K. Kubo, J.-L. Liao, C.-M. Zeng, P.-A. Lidstrom, C. Lindh, A. Palm, T. Srichiayo, L. Valtcheva, R. Zhang, Jpn. J. Electroph. 39 (1995) 1]. Throughout this review we will refer to such packings as monolithic or continuous beds, but they are identical type packings, formed by the in situ polymerization in the capillary or column. CEC capillaries can be much longer, and contain smaller particles than is practical for HPLC. This improves resolution significantly. CEC is able to capitalize on existing mobile phase technology developed over 30 years to improve separations. The requirement that the mobile phase simultaneously promote the separation and mobile phase mobility needs to be considered. In RPLC, this dual role is not much of a problem. It may be much more important in other modes, particularly ion-exchange (IEC). As the field develops, it is becoming clear that CEC is not

  13. Applicability and limitations of enzyme addition assays for the characterisation of soil organic phosphorus across a range of soil types

    NASA Astrophysics Data System (ADS)

    Jarosch, Klaus; Doolette, Ashlea; Smernik, Ronald; Frossard, Emmanuel; Bünemann, Else K.

    2014-05-01

    Solution 31P NMR spectroscopy is a powerful tool for the characterisation and quantification of organic P classes in soil. Potential limitations are due to costs, equipment accessibility and the requirement of relatively large amounts of sample. A recent alternative approach for the quantification of specific organic P classes is the use of substrate-specific phosphohydrolase enzymes which cleave the inorganic orthophosphate from the organic moiety. The released orthophosphate is detectable by colorimetry. Conclusions about the hydrolysed class of organic P can be made based on the comparison of inorganic P concentrations in enzymatically treated and untreated samples. The aim of this study was to test the applicability of enzyme addition assays for the characterisation of organic P classes on a) NaOH-EDTA extracts, b) soil:water filtrates (0.2 μm) and c) soil:water suspensions. The organic P classes in NaOH-EDTA extracts were also determined by 31P NMR spectroscopy, enabling a comparison between methods. Ten topsoil samples from four continents (five cambisols, two ferralsols, two luvisols and one lixisol) with varying total P content (83 - 1,1560 mg kg-1), pHH2O (4.2 - 8.0) and land management (grassland or cropped land) were analysed. Four different classes of organic P were determined by the enzyme addition assay: 1) monoester like-P (by an acid phosphatase known to hydrolyse simple monoesters, pyrophosphate and ATP), 2) DNA-like P (by a nuclease in combination with an acid phosphatase), 3) inositol phosphate-like P (by a phytase known to hydrolyse all monoester like-P plus myo-inositol hexakisphosphate and scyllo-inositol hexakisphosphate) and 4) enzyme stable-P (enzymatically not hydrolysed organic P forms). In the ten topsoil samples, NaOH-EDTA-extractable organic P ranged from 6 - 1,115 mg P kg-1 soil. Of this, 33 - 92 % was enzyme labile, with inositol phosphate-like P being the largest organic P class in most soils (15 - 51%), followed by monoester

  14. Practical and Broadly Applicable Catalytic Enantioselective Additions of Allyl-B(pin) Compounds to Ketones and α-Ketoesters.

    PubMed

    Robbins, Daniel W; Lee, KyungA; Silverio, Daniel L; Volkov, Alexey; Torker, Sebastian; Hoveyda, Amir H

    2016-08-01

    A set of broadly applicable methods for efficient catalytic additions of easy-to-handle allyl-B(pin) (pin=pinacolato) compounds to ketones and acyclic α-ketoesters was developed. Accordingly, a large array of tertiary alcohols can be obtained in 60 to >98 % yield and up to 99:1 enantiomeric ratio. At the heart of this development is rational alteration of the structures of the small-molecule aminophenol-based catalysts. Notably, with ketones, increasing the size of a catalyst moiety (tBu to SiPh3 ) results in much higher enantioselectivity. With α-ketoesters, on the other hand, not only does the opposite hold true, since Me substitution leads to substantially higher enantioselectivity, but the sense of the selectivity is reversed as well.

  15. The potential application of red mud and soil mixture as additive to the surface layer of a landfill cover system.

    PubMed

    Ujaczki, Éva; Feigl, Viktória; Molnár, Mónika; Vaszita, Emese; Uzinger, Nikolett; Erdélyi, Attila; Gruiz, Katalin

    2016-06-01

    Red mud, the by-product of aluminum production, has been regarded as a problematic residue all over the world. Its storage involves risks as evidenced by the Ajka red mud spill, an accident in Hungary where the slurry broke free, flooding the surrounding areas. As an immediate remediation measure more than 5cm thick red mud layer was removed from the flooded soil surface. The removed red mud and soil mixture (RMSM) was transferred into the reservoirs for storage. In this paper the application of RMSM is evaluated in a field study aiming at re-utilizing waste, decreasing cost of waste disposal and providing a value-added product. The purpose was to investigate the applicability of RMSM as surface layer component of landfill cover systems. The field study was carried out in two steps: in lysimeters and in field plots. The RMSM was mixed at ratios ranging between 0 and 50% w/w with low quality subsoil (LQS) originally used as surface layer of an interim landfill cover. The characteristics of the LQS+RMSM mixtures compared to the subsoil (LQS) and the RMSM were determined by physical-chemical, biological and ecotoxicological methods. The addition of RMSM to the subsoil (LQS) at up to 20% did not result any ecotoxic effect, but it increased the water holding capacity. In addition, the microbial substrate utilization became about triple of subsoil (LQS) after 10months. According to our results the RMSM mixed into subsoil (LQS) at 20% w/w dose may be applied as surface layer of landfill cover systems. PMID:27266315

  16. 40 CFR 1045.225 - How do I amend my application for certification to include new or modified engines or change an FEL?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false How do I amend my application for certification to include new or modified engines or change an FEL? 1045.225 Section 1045.225 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM...

  17. Characteristics of concentration-inhibition curves of individual chemicals and applicability of the concentration addition model for mixture toxicity prediction.

    PubMed

    Wang, Na; Wang, Xiaochang C; Ma, Xiaoyan

    2015-03-01

    The concentration addition (CA) model has been widely applied to predict mixture toxicity. However, its applicability is difficult to evaluate due to the complexity of interactions among substances. Considering that the concentration-response curve (CRC) of each component of the mixture is closely related to the prediction of mixture toxicity, mathematical treatments were used to derive a characteristic index kECx (k was the slope of the tangent line of a CRC at concentration ECx). The implication is that the CA model would be applicable for predicting the mixture toxicity only when chemical components have similar kECx in the whole or part of the concentration range. For five selected chemicals whose toxicity was detected using luminescent bacteria, sodium dodecyl benzene sulfonate (SDBS) showed much higher kECx values than the others and its existence in the binary mixtures brought about overestimation of the mixture toxicity with the CA model. The higher the mass ratio of SDBS in a multi-mixture was, the more the toxicity prediction deviated from measurements. By applying the method proposed in this study to analyze some published data, it is confirmed that some components having significantly different kECx values from the other components could explain the large deviation of the mixture toxicity predicted by the CA model. PMID:25499050

  18. Application of the modified additivity rule to the calculation of electron-impact ionization cross sections of complex molecules

    SciTech Connect

    Deutsch, H.; Becker, K.; Basner, R.; Schmidt, M.; Maerk, T.D.

    1998-11-05

    This paper describes the application of the modified additivity rule (MAR) to the calculation of total (counting) electron-impact ionization cross sections of complex molecules with sum formulas of the form A{sub x},B{sub y}, A{sub x},B{sub y},C{sub z}, and A{sub p},B{sub s}C{sub t}D{sub u}. The MAR incorporates weighting factors for the contributions to the molecular ionization cross section from the ionization cross sections of the constituent atoms, which depend explicitly on the atomic radii and the effective number of atomic electrons except for a few special cases (hydrides where the other constituent atom has a radius smaller than the radius of the H atom and species where both constituent atoms have radii smaller than the radius of the H atom), where the weighting factors depend only on the atomic radii, i.e., on geometric effects. A comprehensive comparison of the predictions of the modified additivity rule with available experimental data and with other theoretical predictions is presented.

  19. Measurement of toverline{t} production with additional jet activity, including b quark jets, in the dilepton decay channel using pp collisions at √{s} = 8 {TeV}

    NASA Astrophysics Data System (ADS)

    Khachatryan, V.; Sirunyan, A. M.; Tumasyan, A.; Adam, W.; Asilar, E.; Bergauer, T.; Brandstetter, J.; Brondolin, E.; Dragicevic, M.; Erö, J.; Friedl, M.; Frühwirth, R.; Ghete, V. M.; Hartl, C.; Hörmann, N.; Hrubec, J.; Jeitler, M.; Knünz, V.; König, A.; Krammer, M.; Krätschmer, I.; Liko, D.; Matsushita, T.; Mikulec, I.; Rabady, D.; Rahbaran, B.; Rohringer, H.; Schieck, J.; Schöfbeck, R.; Strauss, J.; Treberer-Treberspurg, W.; Waltenberger, W.; Wulz, C.-E.; Mossolov, V.; Shumeiko, N.; Suarez Gonzalez, J.; Alderweireldt, S.; Cornelis, T.; de Wolf, E. A.; Janssen, X.; Knutsson, A.; Lauwers, J.; Luyckx, S.; van de Klundert, M.; van Haevermaet, H.; van Mechelen, P.; van Remortel, N.; van Spilbeeck, A.; Abu Zeid, S.; Blekman, F.; D'Hondt, J.; Daci, N.; de Bruyn, I.; Deroover, K.; Heracleous, N.; Keaveney, J.; Lowette, S.; Moreels, L.; Olbrechts, A.; Python, Q.; Strom, D.; Tavernier, S.; van Doninck, W.; van Mulders, P.; van Onsem, G. P.; van Parijs, I.; Barria, P.; Brun, H.; Caillol, C.; Clerbaux, B.; de Lentdecker, G.; Fasanella, G.; Favart, L.; Grebenyuk, A.; Karapostoli, G.; Lenzi, T.; Léonard, A.; Maerschalk, T.; Marinov, A.; Perniè, L.; Randle-Conde, A.; Reis, T.; Seva, T.; Vander Velde, C.; Yonamine, R.; Vanlaer, P.; Yonamine, R.; Zenoni, F.; Zhang, F.; Adler, V.; Beernaert, K.; Benucci, L.; Cimmino, A.; Crucy, S.; Dobur, D.; Fagot, A.; Garcia, G.; Gul, M.; McCartin, J.; Ocampo Rios, A. A.; Poyraz, D.; Ryckbosch, D.; Salva, S.; Sigamani, M.; Strobbe, N.; Tytgat, M.; van Driessche, W.; Yazgan, E.; Zaganidis, N.; Basegmez, S.; Beluffi, C.; Bondu, O.; Brochet, S.; Bruno, G.; Caudron, A.; Ceard, L.; da Silveira, G. G.; Delaere, C.; Favart, D.; Forthomme, L.; Giammanco, A.; Hollar, J.; Jafari, A.; Jez, P.; Komm, M.; Lemaitre, V.; Mertens, A.; Musich, M.; Nuttens, C.; Perrini, L.; Pin, A.; Piotrzkowski, K.; Popov, A.; Quertenmont, L.; Selvaggi, M.; Vidal Marono, M.; Beliy, N.; Hammad, G. H.; Júnior, W. L. Aldá; Alves, F. L.; Alves, G. A.; Brito, L.; Correa Martins Junior, M.; Hamer, M.; Hensel, C.; Mora Herrera, C.; Moraes, A.; Pol, M. E.; Rebello Teles, P.; Belchior Batista Das Chagas, E.; Carvalho, W.; Chinellato, J.; Custódio, A.; da Costa, E. M.; de Jesus Damiao, D.; de Oliveira Martins, C.; Fonseca de Souza, S.; Huertas Guativa, L. M.; Malbouisson, H.; Matos Figueiredo, D.; Mundim, L.; Nogima, H.; Prado da Silva, W. L.; Santoro, A.; Sznajder, A.; Tonelli Manganote, E. J.; Vilela Pereira, A.; Ahuja, S.; Bernardes, C. A.; de Souza Santos, A.; Dogra, S.; Fernandez Perez Tomei, T. R.; Gregores, E. M.; Mercadante, P. G.; Moon, C. S.; Novaes, S. F.; Padula, Sandra S.; Romero Abad, D.; Ruiz Vargas, J. C.; Aleksandrov, A.; Hadjiiska, R.; Iaydjiev, P.; Rodozov, M.; Stoykova, S.; Sultanov, G.; Vutova, M.; Dimitrov, A.; Glushkov, I.; Litov, L.; Pavlov, B.; Petkov, P.; Ahmad, M.; Bian, J. G.; Chen, G. M.; Chen, H. S.; Chen, M.; Cheng, T.; Du, R.; Jiang, C. H.; Plestina, R.; Romeo, F.; Shaheen, S. M.; Spiezia, A.; Tao, J.; Wang, C.; Wang, Z.; Zhang, H.; Asawatangtrakuldee, C.; Ban, Y.; Li, Q.; Liu, S.; Mao, Y.; Qian, S. J.; Wang, D.; Xu, Z.; Avila, C.; Cabrera, A.; Chaparro Sierra, L. F.; Florez, C.; Gomez, J. P.; Gomez Moreno, B.; Sanabria, J. C.; Godinovic, N.; Lelas, D.; Puljak, I.; Ribeiro Cipriano, P. M.; Antunovic, Z.; Kovac, M.; Brigljevic, V.; Kadija, K.; Luetic, J.; Micanovic, S.; Sudic, L.; Attikis, A.; Mavromanolakis, G.; Mousa, J.; Nicolaou, C.; Ptochos, F.; Razis, P. A.; Rykaczewski, H.; Bodlak, M.; Finger, M.; Finger, M.; El Sawy, M.; El-Khateeb, E.; Elkafrawy, T.; Mohamed, A.; Salama, E.; Calpas, B.; Kadastik, M.; Murumaa, M.; Raidal, M.; Tiko, A.; Veelken, C.; Eerola, P.; Pekkanen, J.; Voutilainen, M.; Härkönen, J.; Karimäki, V.; Kinnunen, R.; Lampén, T.; Lassila-Perini, K.; Lehti, S.; Lindén, T.; Luukka, P.; Mäenpää, T.; Peltola, T.; Tuominen, E.; Tuominiemi, J.; Tuovinen, E.; Wendland, L.; Talvitie, J.; Tuuva, T.; Besancon, M.; Couderc, F.; Dejardin, M.; Denegri, D.; Fabbro, B.; Faure, J. L.; Favaro, C.; Ferri, F.; Ganjour, S.; Givernaud, A.; Gras, P.; Hamel de Monchenault, G.; Jarry, P.; Locci, E.; Machet, M.; Malcles, J.; Rander, J.; Rosowsky, A.; Titov, M.; Zghiche, A.; Antropov, I.; Baffioni, S.; Beaudette, F.; Busson, P.; Cadamuro, L.; Chapon, E.; Charlot, C.; Dahms, T.; Davignon, O.; Filipovic, N.; Florent, A.; Granier de Cassagnac, R.; Lisniak, S.; Mastrolorenzo, L.; Miné, P.; Naranjo, I. N.; Nguyen, M.; Ochando, C.; Ortona, G.; Paganini, P.; Pigard, P.; Regnard, S.; Salerno, R.; Sauvan, J. B.; Sirois, Y.; Strebler, T.; Yilmaz, Y.; Zabi, A.; Agram, J.-L.; Andrea, J.; Aubin, A.; Bloch, D.; Brom, J.-M.; Buttignol, M.; Chabert, E. C.; Chanon, N.; Collard, C.; Conte, E.; Coubez, X.; Fontaine, J.-C.; Gelé, D.; Goerlach, U.; Goetzmann, C.; Le Bihan, A.-C.; Merlin, J. A.; Skovpen, K.; van Hove, P.; Gadrat, S.; Beauceron, S.; Bernet, C.; Boudoul, G.; Bouvier, E.; Carrillo Montoya, C. A.; Chierici, R.; Contardo, D.; Courbon, B.; Depasse, P.; El Mamouni, H.; Fan, J.; Fay, J.; Gascon, S.; Gouzevitch, M.; Ille, B.; Lagarde, F.; Laktineh, I. B.; Lethuillier, M.; Mirabito, L.; Pequegnot, A. L.; Perries, S.; Ruiz Alvarez, J. D.; Sabes, D.; Sgandurra, L.; Sordini, V.; Vander Donckt, M.; Verdier, P.; Viret, S.; Toriashvili, T.; Lomidze, D.; Autermann, C.; Beranek, S.; Edelhoff, M.; Feld, L.; Heister, A.; Kiesel, M. K.; Klein, K.; Lipinski, M.; Ostapchuk, A.; Preuten, M.; Raupach, F.; Schael, S.; Schulte, J. F.; Verlage, T.; Weber, H.; Wittmer, B.; Zhukov, V.; Ata, M.; Brodski, M.; Dietz-Laursonn, E.; Duchardt, D.; Endres, M.; Erdmann, M.; Erdweg, S.; Esch, T.; Fischer, R.; Güth, A.; Hebbeker, T.; Heidemann, C.; Hoepfner, K.; Klingebiel, D.; Knutzen, S.; Kreuzer, P.; Merschmeyer, M.; Meyer, A.; Millet, P.; Olschewski, M.; Padeken, K.; Papacz, P.; Pook, T.; Radziej, M.; Reithler, H.; Rieger, M.; Scheuch, F.; Sonnenschein, L.; Teyssier, D.; Thüer, S.; Cherepanov, V.; Erdogan, Y.; Flügge, G.; Geenen, H.; Geisler, M.; Hoehle, F.; Kargoll, B.; Kress, T.; Kuessel, Y.; Künsken, A.; Lingemann, J.; Nehrkorn, A.; Nowack, A.; Nugent, I. M.; Pistone, C.; Pooth, O.; Stahl, A.; Aldaya Martin, M.; Asin, I.; Bartosik, N.; Behnke, O.; Behrens, U.; Bell, A. J.; Borras, K.; Burgmeier, A.; Campbell, A.; Choudhury, S.; Costanza, F.; Diez Pardos, C.; Dolinska, G.; Dooling, S.; Dorland, T.; Eckerlin, G.; Eckstein, D.; Eichhorn, T.; Flucke, G.; Gallo, E.; Garcia, J. Garay; Geiser, A.; Gizhko, A.; Gunnellini, P.; Hauk, J.; Hempel, M.; Jung, H.; Kalogeropoulos, A.; Karacheban, O.; Kasemann, M.; Katsas, P.; Kieseler, J.; Kleinwort, C.; Korol, I.; Lange, W.; Leonard, J.; Lipka, K.; Lobanov, A.; Lohmann, W.; Mankel, R.; Marfin, I.; Melzer-Pellmann, I.-A.; Meyer, A. B.; Mittag, G.; Mnich, J.; Mussgiller, A.; Naumann-Emme, S.; Nayak, A.; Ntomari, E.; Perrey, H.; Pitzl, D.; Placakyte, R.; Raspereza, A.; Roland, B.; Sahin, M. Ö.; Saxena, P.; Schoerner-Sadenius, T.; Schröder, M.; Seitz, C.; Spannagel, S.; Trippkewitz, K. D.; Walsh, R.; Wissing, C.; Blobel, V.; Centis Vignali, M.; Draeger, A. R.; Erfle, J.; Garutti, E.; Goebel, K.; Gonzalez, D.; Görner, M.; Haller, J.; Hoffmann, M.; Höing, R. S.; Junkes, A.; Klanner, R.; Kogler, R.; Lapsien, T.; Lenz, T.; Marchesini, I.; Marconi, D.; Meyer, M.; Nowatschin, D.; Ott, J.; Pantaleo, F.; Peiffer, T.; Perieanu, A.; Pietsch, N.; Poehlsen, J.; Rathjens, D.; Sander, C.; Schettler, H.; Schleper, P.; Schlieckau, E.; Schmidt, A.; Schwandt, J.; Sola, V.; Stadie, H.; Steinbrück, G.; Tholen, H.; Troendle, D.; Usai, E.; Vanelderen, L.; Vanhoefer, A.; Vormwald, B.; Akbiyik, M.; Barth, C.; Baus, C.; Berger, J.; Böser, C.; Butz, E.; Chwalek, T.; Colombo, F.; de Boer, W.; Descroix, A.; Dierlamm, A.; Fink, S.; Frensch, F.; Friese, R.; Giffels, M.; Gilbert, A.; Haitz, D.; Hartmann, F.; Heindl, S. M.; Husemann, U.; Katkov, I.; Kornmayer, A.; Lobelle Pardo, P.; Maier, B.; Mildner, H.; Mozer, M. U.; Müller, T.; Müller, Th.; Plagge, M.; Quast, G.; Rabbertz, K.; Röcker, S.; Roscher, F.; Sieber, G.; Simonis, H. J.; Stober, F. M.; Ulrich, R.; Wagner-Kuhr, J.; Wayand, S.; Weber, M.; Weiler, T.; Wöhrmann, C.; Wolf, R.; Anagnostou, G.; Daskalakis, G.; Geralis, T.; Giakoumopoulou, V. A.; Kyriakis, A.; Loukas, D.; Psallidas, A.; Topsis-Giotis, I.; Agapitos, A.; Kesisoglou, S.; Panagiotou, A.; Saoulidou, N.; Tziaferi, E.; Evangelou, I.; Flouris, G.; Foudas, C.; Kokkas, P.; Loukas, N.; Manthos, N.; Papadopoulos, I.; Paradas, E.; Strologas, J.; Bencze, G.; Hajdu, C.; Hazi, A.; Hidas, P.; Horvath, D.; Sikler, F.; Veszpremi, V.; Vesztergombi, G.; Zsigmond, A. J.; Beni, N.; Czellar, S.; Karancsi, J.; Molnar, J.; Szillasi, Z.; Bartók, M.; Makovec, A.; Raics, P.; Trocsanyi, Z. L.; Ujvari, B.; Mal, P.; Mandal, K.; Sahoo, D. K.; Sahoo, N.; Swain, S. K.; Bansal, S.; Beri, S. B.; Bhatnagar, V.; Chawla, R.; Gupta, R.; Bhawandeep, U.; Kalsi, A. K.; Kaur, A.; Kaur, M.; Kumar, R.; Mehta, A.; Mittal, M.; Singh, J. B.; Walia, G.; Kumar, Ashok; Bhardwaj, A.; Choudhary, B. C.; Garg, R. B.; Kumar, A.; Malhotra, S.; Naimuddin, M.; Nishu, N.; Ranjan, K.; Sharma, R.; Sharma, V.; Bhattacharya, S.; Chatterjee, K.; Dey, S.; Dutta, S.; Jain, Sa.; Majumdar, N.; Modak, A.; Mondal, K.; Mukherjee, S.; Mukhopadhyay, S.; Roy, A.; Roy, D.; Roy Chowdhury, S.; Sarkar, S.; Sharan, M.; Abdulsalam, A.; Chudasama, R.; Dutta, D.; Jha, V.; Kumar, V.; Mohanty, A. K.; Pant, L. M.; Shukla, P.; Topkar, A.; Aziz, T.; Banerjee, S.; Bhowmik, S.; Chatterjee, R. M.; Dewanjee, R. K.; Dugad, S.; Ganguly, S.; Ghosh, S.; Guchait, M.; Gurtu, A.; Kole, G.; Kumar, S.; Mahakud, B.; Maity, M.; Majumder, G.; Mazumdar, K.; Mitra, S.; Mohanty, G. B.; Parida, B.; Sarkar, T.; Sur, N.; Sutar, B.; Wickramage, N.; Chauhan, S.; Dube, S.; Sharma, S.; Bakhshiansohi, H.; Behnamian, H.; Etesami, S. M.; Fahim, A.; Goldouzian, R.; Khakzad, M.; Mohammadi Najafabadi, M.; Naseri, M.; Paktinat Mehdiabadi, S.; Rezaei Hosseinabadi, F.; Safarzadeh, B.; Zeinali, M.; Felcini, M.; Grunewald, M.; Abbrescia, M.; Calabria, C.; Caputo, C.; Colaleo, A.; Creanza, D.; Cristella, L.; de Filippis, N.; de Palma, M.; Fiore, L.; Iaselli, G.; Maggi, G.; Miniello, G.; Maggi, M.; My, S.; Nuzzo, S.; Pompili, A.; Pugliese, G.; Radogna, R.; Ranieri, A.; Selvaggi, G.; Silvestris, L.; Venditti, R.; Verwilligen, P.; Abbiendi, G.; Battilana, C.; Benvenuti, A. C.; Bonacorsi, D.; Braibant-Giacomelli, S.; Brigliadori, L.; Campanini, R.; Capiluppi, P.; Castro, A.; Cavallo, F. R.; Chhibra, S. S.; Codispoti, G.; Cuffiani, M.; Dallavalle, G. M.; Fabbri, F.; Fanfani, A.; Fasanella, D.; Giacomelli, P.; Grandi, C.; Guiducci, L.; Marcellini, S.; Masetti, G.; Montanari, A.; Navarria, F. L.; Perrotta, A.; Rossi, A. M.; Primavera, F.; Rovelli, T.; Siroli, G. P.; Tosi, N.; Travaglini, R.; Cappello, G.; Chiorboli, M.; Costa, S.; di Mattia, A.; Giordano, F.; Potenza, R.; Tricomi, A.; Tuve, C.; Barbagli, G.; Ciulli, V.; Civinini, C.; D'Alessandro, R.; Focardi, E.; Gonzi, S.; Gori, V.; Lenzi, P.; Meschini, M.; Paoletti, S.; Sguazzoni, G.; Tropiano, A.; Viliani, L.; Benussi, L.; Bianco, S.; Fabbri, F.; Piccolo, D.; Primavera, F.; Calvelli, V.; Ferro, F.; Lo Vetere, M.; Monge, M. R.; Robutti, E.; Tosi, S.; Brianza, L.; Dinardo, M. E.; Fiorendi, S.; Gennai, S.; Gerosa, R.; Ghezzi, A.; Govoni, P.; Malvezzi, S.; Manzoni, R. A.; Marzocchi, B.; Menasce, D.; Moroni, L.; Paganoni, M.; Pedrini, D.; Ragazzi, S.; Redaelli, N.; Tabarelli de Fatis, T.; Buontempo, S.; Cavallo, N.; di Guida, S.; Esposito, M.; Fabozzi, F.; Iorio, A. O. M.; Lanza, G.; Lista, L.; Meola, S.; Merola, M.; Paolucci, P.; Sciacca, C.; Thyssen, F.; Azzi, P.; Bacchetta, N.; Bellato, M.; Benato, L.; Bisello, D.; Boletti, A.; Carlin, R.; Checchia, P.; Dall'Osso, M.; Dorigo, T.; Dosselli, U.; Fanzago, F.; Gasparini, F.; Gasparini, U.; Gonella, F.; Gozzelino, A.; Lacaprara, S.; Margoni, M.; Meneguzzo, A. T.; Pazzini, J.; Pozzobon, N.; Ronchese, P.; Simonetto, F.; Torassa, E.; Tosi, M.; Zanetti, M.; Zotto, P.; Zucchetta, A.; Zumerle, G.; Braghieri, A.; Magnani, A.; Montagna, P.; Ratti, S. P.; Re, V.; Riccardi, C.; Salvini, P.; Vai, I.; Vitulo, P.; Alunni Solestizi, L.; Biasini, M.; Bilei, G. M.; Ciangottini, D.; Fanò, L.; Lariccia, P.; Mantovani, G.; Menichelli, M.; Saha, A.; Santocchia, A.; Androsov, K.; Azzurri, P.; Bagliesi, G.; Bernardini, J.; Boccali, T.; Castaldi, R.; Ciocci, M. A.; Dell'Orso, R.; Donato, S.; Fedi, G.; Fiori, F.; Foà, L.; Giassi, A.; Grippo, M. T.; Ligabue, F.; Lomtadze, T.; Martini, L.; Messineo, A.; Palla, F.; Rizzi, A.; Savoy-Navarro, A.; Serban, A. T.; Spagnolo, P.; Tenchini, R.; Tonelli, G.; Venturi, A.; Verdini, P. G.; Barone, L.; Cavallari, F.; D'Imperio, G.; Del Re, D.; Diemoz, M.; Gelli, S.; Jorda, C.; Longo, E.; Margaroli, F.; Meridiani, P.; Organtini, G.; Paramatti, R.; Preiato, F.; Rahatlou, S.; Rovelli, C.; Santanastasio, F.; Traczyk, P.; Amapane, N.; Arcidiacono, R.; Argiro, S.; Arneodo, M.; Bellan, R.; Biino, C.; Cartiglia, N.; Costa, M.; Covarelli, R.; Degano, A.; Demaria, N.; Finco, L.; Kiani, B.; Mariotti, C.; Maselli, S.; Migliore, E.; Monaco, V.; Monteil, E.; Obertino, M. M.; Pacher, L.; Pastrone, N.; Pelliccioni, M.; Pinna Angioni, G. L.; Ravera, F.; Potenza, A.; Romero, A.; Ruspa, M.; Sacchi, R.; Solano, A.; Staiano, A.; Tamponi, U.; Belforte, S.; Candelise, V.; Casarsa, M.; Cossutti, F.; Della Ricca, G.; Gobbo, B.; La Licata, C.; Marone, M.; Schizzi, A.; Zanetti, A.; Kropivnitskaya, T. A.; Nam, S. K.; Kim, D. H.; Kim, G. N.; Kim, M. S.; Kim, M. S.; Kong, D. J.; Lee, S.; Oh, Y. D.; Sakharov, A.; Son, D. C.; Brochero Cifuentes, J. A.; Kim, H.; Kim, T. J.; Song, S.; Choi, S.; Go, Y.; Gyun, D.; Hong, B.; Jo, M.; Kim, H.; Kim, Y.; Lee, B.; Lee, K.; Lee, K. S.; Lee, S.; Lee, S.; Park, S. K.; Roh, Y.; Yoo, H. D.; Choi, M.; Kim, H.; Kim, J. H.; Lee, J. S. H.; Park, I. C.; Ryu, G.; Ryu, M. S.; Choi, Y.; Goh, J.; Kim, D.; Kwon, E.; Lee, J.; Yu, I.; Juodagalvis, A.; Vaitkus, J.; Ahmed, I.; Ibrahim, Z. A.; Komaragiri, J. R.; Md Ali, M. A. B.; Mohamad Idris, F.; Wan Abdullah, W. A. T.; Yusli, M. N.; Wan Abdullah, W. A. T.; Casimiro Linares, E.; Castilla-Valdez, H.; de La Cruz-Burelo, E.; Heredia-de La Cruz, I.; Hernandez-Almada, A.; Lopez-Fernandez, R.; Sanchez-Hernandez, A.; Carrillo Moreno, S.; Vazquez Valencia, F.; Pedraza, I.; Salazar Ibarguen, H. A.; Morelos Pineda, A.; Krofcheck, D.; Butler, P. H.; Ahmad, A.; Ahmad, M.; Hassan, Q.; Hoorani, H. R.; Khan, W. A.; Khurshid, T.; Shoaib, M.; Bialkowska, H.; Bluj, M.; Boimska, B.; Frueboes, T.; Górski, M.; Kazana, M.; Nawrocki, K.; Romanowska-Rybinska, K.; Szleper, M.; Zalewski, P.; Brona, G.; Bunkowski, K.; Byszuk, A.; Doroba, K.; Kalinowski, A.; Konecki, M.; Krolikowski, J.; Misiura, M.; Olszewski, M.; Walczak, M.; Bargassa, P.; da Cruz E Silva, C. Beir Ao; di Francesco, A.; Faccioli, P.; Parracho, P. G. Ferreira; Gallinaro, M.; Leonardo, N.; Lloret Iglesias, L.; Nguyen, F.; Rodrigues Antunes, J.; Seixas, J.; Toldaiev, O.; Vadruccio, D.; Varela, J.; Vischia, P.; Afanasiev, S.; Bunin, P.; Gavrilenko, M.; Golutvin, I.; Gorbunov, I.; Kamenev, A.; Karjavin, V.; Konoplyanikov, V.; Lanev, A.; Malakhov, A.; Matveev, V.; Moisenz, P.; Palichik, V.; Perelygin, V.; Savina, M.; Shmatov, S.; Shulha, S.; Smirnov, V.; Zarubin, A.; Golovtsov, V.; Ivanov, Y.; Kim, V.; Kuznetsova, E.; Levchenko, P.; Murzin, V.; Oreshkin, V.; Smirnov, I.; Sulimov, V.; Uvarov, L.; Vavilov, S.; Vorobyev, A.; Andreev, Yu.; Dermenev, A.; Gninenko, S.; Golubev, N.; Karneyeu, A.; Kirsanov, M.; Krasnikov, N.; Pashenkov, A.; Tlisov, D.; Toropin, A.; Epshteyn, V.; Gavrilov, V.; Lychkovskaya, N.; Popov, V.; Pozdnyakov, L.; Safronov, G.; Spiridonov, A.; Vlasov, E.; Zhokin, A.; Bylinkin, A.; Andreev, V.; Azarkin, M.; Dremin, I.; Kirakosyan, M.; Leonidov, A.; Mesyats, G.; Rusakov, S. V.; Baskakov, A.; Belyaev, A.; Boos, E.; Bunichev, V.; Dubinin, M.; Dudko, L.; Klyukhin, V.; Kodolova, O.; Korneeva, N.; Lokhtin, I.; Myagkov, I.; Obraztsov, S.; Perfilov, M.; Petrushanko, S.; Savrin, V.; Azhgirey, I.; Bayshev, I.; Bitioukov, S.; Kachanov, V.; Kalinin, A.; Konstantinov, D.; Krychkine, V.; Petrov, V.; Ryutin, R.; Sobol, A.; Tourtchanovitch, L.; Troshin, S.; Tyurin, N.; Uzunian, A.; Volkov, A.; Adzic, P.; Milosevic, J.; Rekovic, V.; Alcaraz Maestre, J.; Battilana, C.; Calvo, E.; Cerrada, M.; Chamizo Llatas, M.; Colino, N.; de La Cruz, B.; Delgado Peris, A.; Domínguez Vázquez, D.; Escalante Del Valle, A.; Fernandez Bedoya, C.; Ramos, J. P. Fernández; Flix, J.; Fouz, M. C.; Garcia-Abia, P.; Gonzalez Lopez, O.; Goy Lopez, S.; Hernandez, J. M.; Josa, M. I.; Navarro de Martino, E.; Yzquierdo, A. Pérez-Calero; Puerta Pelayo, J.; Quintario Olmeda, A.; Redondo, I.; Romero, L.; Santaolalla, J.; Soares, M. S.; Albajar, C.; de Trocóniz, J. F.; Missiroli, M.; Moran, D.; Cuevas, J.; Fernandez Menendez, J.; Folgueras, S.; Gonzalez Caballero, I.; Palencia Cortezon, E.; Vizan Garcia, J. M.; Cabrillo, I. J.; Calderon, A.; Castiñeiras de Saa, J. R.; de Castro Manzano, P.; Duarte Campderros, J.; Fernandez, M.; Garcia-Ferrero, J.; Gomez, G.; Lopez Virto, A.; Marco, J.; Marco, R.; Martinez Rivero, C.; Matorras, F.; Munoz Sanchez, F. J.; Piedra Gomez, J.; Rodrigo, T.; Rodríguez-Marrero, A. Y.; Ruiz-Jimeno, A.; Scodellaro, L.; Trevisani, N.; Vila, I.; Vilar Cortabitarte, R.; Abbaneo, D.; Auffray, E.; Auzinger, G.; Bachtis, M.; Baillon, P.; Ball, A. H.; Barney, D.; Benaglia, A.; Bendavid, J.; Benhabib, L.; Benitez, J. F.; Berruti, G. M.; Bloch, P.; Bocci, A.; Bonato, A.; Botta, C.; Breuker, H.; Camporesi, T.; Castello, R.; Cerminara, G.; D'Alfonso, M.; D'Enterria, D.; Dabrowski, A.; Daponte, V.; David, A.; de Gruttola, M.; de Guio, F.; de Roeck, A.; de Visscher, S.; di Marco, E.; Dobson, M.; Dordevic, M.; Dorney, B.; Du Pree, T.; Dünser, M.; Dupont, N.; Elliott-Peisert, A.; Franzoni, G.; Funk, W.; Gigi, D.; Gill, K.; Giordano, D.; Girone, M.; Glege, F.; Guida, R.; Gundacker, S.; Guthoff, M.; Hammer, J.; Harris, P.; Hegeman, J.; Innocente, V.; Janot, P.; Kirschenmann, H.; Kortelainen, M. J.; Kousouris, K.; Krajczar, K.; Lecoq, P.; Lourenço, C.; Lucchini, M. T.; Magini, N.; Malgeri, L.; Mannelli, M.; Martelli, A.; Masetti, L.; Meijers, F.; Mersi, S.; Meschi, E.; Moortgat, F.; Morovic, S.; Mulders, M.; Nemallapudi, M. V.; Neugebauer, H.; Orfanelli, S.; Orsini, L.; Pape, L.; Perez, E.; Peruzzi, M.; Petrilli, A.; Petrucciani, G.; Pfeiffer, A.; Piparo, D.; Racz, A.; Rolandi, G.; Rovere, M.; Ruan, M.; Sakulin, H.; Schäfer, C.; Schwick, C.; Seidel, M.; Sharma, A.; Silva, P.; Simon, M.; Sphicas, P.; Steggemann, J.; Stieger, B.; Stoye, M.; Takahashi, Y.; Treille, D.; Triossi, A.; Tsirou, A.; Veres, G. I.; Wardle, N.; Wöhri, H. K.; Zagozdzinska, A.; Zeuner, W. D.; Bertl, W.; Deiters, K.; Erdmann, W.; Horisberger, R.; Ingram, Q.; Kaestli, H. C.; Kotlinski, D.; Langenegger, U.; Renker, D.; Rohe, T.; Bachmair, F.; Bäni, L.; Bianchini, L.; Casal, B.; Dissertori, G.; Dittmar, M.; Donegà, M.; Eller, P.; Grab, C.; Heidegger, C.; Hits, D.; Hoss, J.; Kasieczka, G.; Lustermann, W.; Mangano, B.; Marionneau, M.; Martinez Ruiz Del Arbol, P.; Masciovecchio, M.; Meister, D.; Micheli, F.; Musella, P.; Nessi-Tedaldi, F.; Pandolfi, F.; Pata, J.; Pauss, F.; Perrozzi, L.; Quittnat, M.; Rossini, M.; Starodumov, A.; Takahashi, M.; Tavolaro, V. R.; Theofilatos, K.; Wallny, R.; Aarrestad, T. K.; Amsler, C.; Caminada, L.; Canelli, M. F.; Chiochia, V.; de Cosa, A.; Galloni, C.; Hinzmann, A.; Hreus, T.; Kilminster, B.; Lange, C.; Ngadiuba, J.; Pinna, D.; Robmann, P.; Ronga, F. J.; Salerno, D.; Yang, Y.; Cardaci, M.; Chen, K. H.; Doan, T. H.; Jain, Sh.; Khurana, R.; Konyushikhin, M.; Kuo, C. M.; Lin, W.; Lu, Y. J.; Yu, S. S.; Kumar, Arun; Bartek, R.; Chang, P.; Chang, Y. H.; Chao, Y.; Chen, K. F.; Chen, P. H.; Dietz, C.; Fiori, F.; Grundler, U.; Hou, W.-S.; Hsiung, Y.; Liu, Y. F.; Lu, R.-S.; Miñano Moya, M.; Petrakou, E.; Tsai, J. F.; Tzeng, Y. M.; Asavapibhop, B.; Kovitanggoon, K.; Singh, G.; Srimanobhas, N.; Suwonjandee, N.; Adiguzel, A.; Cerci, S.; Demiroglu, Z. S.; Dozen, C.; Dumanoglu, I.; Girgis, S.; Gokbulut, G.; Guler, Y.; Guler, Y.; Gurpinar, E.; Hos, I.; Kangal, E. E.; Kayis Topaksu, A.; Onengut, G.; Ozdemir, K.; Ozturk, S.; Tali, B.; Topakli, H.; Vergili, M.; Zorbilmez, C.; Akin, I. V.; Bilin, B.; Bilmis, S.; Isildak, B.; Karapinar, G.; Yalvac, M.; Zeyrek, M.; Gülmez, E.; Kaya, M.; Kaya, O.; Yetkin, E. A.; Yetkin, T.; Cakir, A.; Cankocak, K.; Sen, S.; Vardarlı, F. I.; Grynyov, B.; Levchuk, L.; Sorokin, P.; Aggleton, R.; Ball, F.; Beck, L.; Brooke, J. J.; Clement, E.; Cussans, D.; Flacher, H.; Goldstein, J.; Grimes, M.; Heath, G. P.; Heath, H. F.; Jacob, J.; Kreczko, L.; Lucas, C.; Meng, Z.; Newbold, D. M.; Paramesvaran, S.; Poll, A.; Sakuma, T.; Seif El Nasr-Storey, S.; Senkin, S.; Smith, D.; Smith, V. J.; Bell, K. W.; Belyaev, A.; Brew, C.; Brown, R. M.; Calligaris, L.; Cieri, D.; Cockerill, D. J. A.; Coughlan, J. A.; Harder, K.; Harper, S.; Olaiya, E.; Petyt, D.; Shepherd-Themistocleous, C. H.; Thea, A.; Tomalin, I. R.; Williams, T.; Womersley, W. J.; Worm, S. D.; Baber, M.; Bainbridge, R.; Buchmuller, O.; Bundock, A.; Burton, D.; Casasso, S.; Citron, M.; Colling, D.; Corpe, L.; Cripps, N.; Dauncey, P.; Davies, G.; de Wit, A.; Della Negra, M.; Dunne, P.; Elwood, A.; Elwood, A.; Ferguson, W.; Fulcher, J.; Futyan, D.; Hall, G.; Iles, G.; Kenzie, M.; Lane, R.; Lucas, R.; Lyons, L.; Magnan, A.-M.; Malik, S.; Nash, J.; Nikitenko, A.; Pela, J.; Pesaresi, M.; Petridis, K.; Raymond, D. M.; Richards, A.; Rose, A.; Seez, C.; Tapper, A.; Uchida, K.; Vazquez Acosta, M.; Virdee, T.; Zenz, S. C.; Cole, J. E.; Hobson, P. R.; Khan, A.; Kyberd, P.; Leggat, D.; Leslie, D.; Reid, I. D.; Symonds, P.; Teodorescu, L.; Turner, M.; Borzou, A.; Call, K.; Dittmann, J.; Hatakeyama, K.; Liu, H.; Pastika, N.; Scarborough, T.; Wu, Z.; Charaf, O.; Cooper, S. I.; Henderson, C.; Rumerio, P.; Arcaro, D.; Avetisyan, A.; Bose, T.; Fantasia, C.; Gastler, D.; Lawson, P.; Rankin, D.; Richardson, C.; Rohlf, J.; St. John, J.; Sulak, L.; Zou, D.; Alimena, J.; Berry, E.; Bhattacharya, S.; Cutts, D.; Dhingra, N.; Ferapontov, A.; Garabedian, A.; Hakala, J.; Heintz, U.; Laird, E.; Landsberg, G.; Mao, Z.; Narain, M.; Piperov, S.; Sagir, S.; Syarif, R.; Breedon, R.; Breto, G.; de La Barca Sanchez, M. Calderon; Chauhan, S.; Chertok, M.; Conway, J.; Conway, R.; Cox, P. T.; Erbacher, R.; Gardner, M.; Ko, W.; Lander, R.; Mulhearn, M.; Pellett, D.; Pilot, J.; Ricci-Tam, F.; Shalhout, S.; Smith, J.; Squires, M.; Stolp, D.; Tripathi, M.; Wilbur, S.; Yohay, R.; Cousins, R.; Everaerts, P.; Farrell, C.; Hauser, J.; Ignatenko, M.; Saltzberg, D.; Valuev, V.; Weber, M.; Burt, K.; Clare, R.; Ellison, J.; Gary, J. W.; Hanson, G.; Heilman, J.; Ivova Paneva, M.; Jandir, P.; Kennedy, E.; Lacroix, F.; Long, O. R.; Luthra, A.; Malberti, M.; Negrete, M. Olmedo; Shrinivas, A.; Wei, H.; Wimpenny, S.; Yates, B. R.; Branson, J. G.; Cerati, G. B.; Cittolin, S.; D'Agnolo, R. T.; Derdzinski, M.; Holzner, A.; Kelley, R.; Klein, D.; Letts, J.; MacNeill, I.; Olivito, D.; Padhi, S.; Pieri, M.; Sani, M.; Sharma, V.; Simon, S.; Tadel, M.; Tu, Y.; Vartak, A.; Wasserbaech, S.; Welke, C.; Würthwein, F.; Yagil, A.; Zevi Della Porta, G.; Bradmiller-Feld, J.; Campagnari, C.; Dishaw, A.; Dutta, V.; Flowers, K.; Franco Sevilla, M.; Geffert, P.; George, C.; Golf, F.; Gouskos, L.; Gran, J.; Incandela, J.; McColl, N.; Mullin, S. D.; Mullin, S. D.; Richman, J.; Stuart, D.; Suarez, I.; West, C.; Yoo, J.; Anderson, D.; Apresyan, A.; Bornheim, A.; Bunn, J.; Chen, Y.; Duarte, J.; Mott, A.; Newman, H. B.; Pena, C.; Pierini, M.; Spiropulu, M.; Vlimant, J. R.; Xie, S.; Zhu, R. Y.; Andrews, M. B.; Azzolini, V.; Calamba, A.; Carlson, B.; Ferguson, T.; Paulini, M.; Russ, J.; Sun, M.; Vogel, H.; Vorobiev, I.; Cumalat, J. P.; Ford, W. T.; Gaz, A.; Jensen, F.; Johnson, A.; Krohn, M.; Mulholland, T.; Nauenberg, U.; Stenson, K.; Wagner, S. R.; Alexander, J.; Chatterjee, A.; Chaves, J.; Chu, J.; Dittmer, S.; Eggert, N.; Mirman, N.; Nicolas Kaufman, G.; Patterson, J. R.; Rinkevicius, A.; Ryd, A.; Skinnari, L.; Soffi, L.; Sun, W.; Tan, S. M.; Teo, W. D.; Thom, J.; Thompson, J.; Tucker, J.; Weng, Y.; Wittich, P.; Abdullin, S.; Albrow, M.; Anderson, J.; Apollinari, G.; Banerjee, S.; Bauerdick, L. A. T.; Beretvas, A.; Berryhill, J.; Bhat, P. C.; Bolla, G.; Burkett, K.; Butler, J. N.; Cheung, H. W. K.; Chlebana, F.; Cihangir, S.; Elvira, V. D.; Fisk, I.; Freeman, J.; Gottschalk, E.; Gray, L.; Green, D.; Grünendahl, S.; Gutsche, O.; Hanlon, J.; Hare, D.; Harris, R. M.; Hasegawa, S.; Hirschauer, J.; Hu, Z.; Jindariani, S.; Johnson, M.; Joshi, U.; Jung, A. W.; Klima, B.; Kreis, B.; Kwan, S.; Lammel, S.; Linacre, J.; Lincoln, D.; Lipton, R.; Liu, T.; Lopes de Sá, R.; Lykken, J.; Maeshima, K.; Marraffino, J. M.; Martinez Outschoorn, V. I.; Maruyama, S.; Mason, D.; McBride, P.; Merkel, P.; Mishra, K.; Mrenna, S.; Nahn, S.; Newman-Holmes, C.; O'Dell, V.; Pedro, K.; Prokofyev, O.; Rakness, G.; Sexton-Kennedy, E.; Soha, A.; Spalding, W. J.; Spiegel, L.; Taylor, L.; Tkaczyk, S.; Tran, N. V.; Uplegger, L.; Vaandering, E. W.; Vernieri, C.; Verzocchi, M.; Vidal, R.; Weber, H. A.; Whitbeck, A.; Yang, F.; Acosta, D.; Avery, P.; Bortignon, P.; Bourilkov, D.; Carnes, A.; Carver, M.; Curry, D.; Das, S.; di Giovanni, G. P.; Field, R. D.; Furic, I. K.; Gleyzer, S. V.; Hugon, J.; Konigsberg, J.; Korytov, A.; Low, J. F.; Ma, P.; Matchev, K.; Mei, H.; Milenovic, P.; Mitselmakher, G.; Rank, D.; Rossin, R.; Shchutska, L.; Snowball, M.; Sperka, D.; Terentyev, N.; Thomas, L.; Wang, J.; Wang, S.; Yelton, J.; Hewamanage, S.; Linn, S.; Markowitz, P.; Martinez, G.; Rodriguez, J. L.; Adams, J. R.; Ackert, A.; Adams, T.; Askew, A.; Bochenek, J.; Diamond, B.; Haas, J.; Hagopian, S.; Hagopian, V.; Johnson, K. F.; Khatiwada, A.; Prosper, H.; Weinberg, M.; Baarmand, M. M.; Bhopatkar, V.; Colafranceschi, S.; Hohlmann, M.; Kalakhety, H.; Noonan, D.; Roy, T.; Yumiceva, F.; Adams, M. R.; Apanasevich, L.; Berry, D.; Betts, R. R.; Bucinskaite, I.; Cavanaugh, R.; Evdokimov, O.; Gauthier, L.; Gerber, C. E.; Hofman, D. J.; Kurt, P.; O'Brien, C.; Sandoval Gonzalez, L. D.; Silkworth, C.; Turner, P.; Varelas, N.; Wu, Z.; Zakaria, M.; Bilki, B.; Clarida, W.; Dilsiz, K.; Durgut, S.; Gandrajula, R. P.; Haytmyradov, M.; Khristenko, V.; Merlo, J.-P.; Mermerkaya, H.; Mestvirishvili, A.; Moeller, A.; Nachtman, J.; Ogul, H.; Onel, Y.; Ozok, F.; Penzo, A.; Snyder, C.; Tiras, E.; Wetzel, J.; Yi, K.; Anderson, I.; Anderson, I.; Barnett, B. A.; Blumenfeld, B.; Eminizer, N.; Fehling, D.; Feng, L.; Gritsan, A. V.; Maksimovic, P.; Martin, C.; Osherson, M.; Roskes, J.; Sady, A.; Sarica, U.; Swartz, M.; Xiao, M.; Xin, Y.; You, C.; Xiao, M.; Baringer, P.; Bean, A.; Benelli, G.; Bruner, C.; Kenny, R. P.; Majumder, D.; Majumder, D.; Malek, M.; Murray, M.; Sanders, S.; Stringer, R.; Wang, Q.; Ivanov, A.; Kaadze, K.; Khalil, S.; Makouski, M.; Maravin, Y.; Mohammadi, A.; Saini, L. K.; Skhirtladze, N.; Toda, S.; Lange, D.; Rebassoo, F.; Wright, D.; Anelli, C.; Baden, A.; Baron, O.; Belloni, A.; Calvert, B.; Eno, S. C.; Ferraioli, C.; Gomez, J. A.; Hadley, N. J.; Jabeen, S.; Jabeen, S.; Kellogg, R. G.; Kolberg, T.; Kunkle, J.; Lu, Y.; Mignerey, A. C.; Shin, Y. H.; Skuja, A.; Tonjes, M. B.; Tonwar, S. C.; Apyan, A.; Barbieri, R.; Baty, A.; Bierwagen, K.; Brandt, S.; Bierwagen, K.; Busza, W.; Cali, I. A.; Demiragli, Z.; Di Matteo, L.; Gomez Ceballos, G.; Goncharov, M.; Gulhan, D.; Iiyama, Y.; Innocenti, G. M.; Klute, M.; Kovalskyi, D.; Lai, Y. S.; Lee, Y.-J.; Levin, A.; Luckey, P. D.; Marini, A. C.; McGinn, C.; Mironov, C.; Narayanan, S.; Niu, X.; Paus, C.; Ralph, D.; Roland, C.; Roland, G.; Salfeld-Nebgen, J.; Stephans, G. S. F.; Sumorok, K.; Varma, M.; Velicanu, D.; Veverka, J.; Wang, J.; Wang, T. W.; Wyslouch, B.; Yang, M.; Zhukova, V.; Dahmes, B.; Evans, A.; Finkel, A.; Gude, A.; Hansen, P.; Kalafut, S.; Kao, S. C.; Klapoetke, K.; Kubota, Y.; Lesko, Z.; Mans, J.; Nourbakhsh, S.; Ruckstuhl, N.; Rusack, R.; Tambe, N.; Turkewitz, J.; Acosta, J. G.; Oliveros, S.; Avdeeva, E.; Bloom, K.; Bose, S.; Claes, D. R.; Dominguez, A.; Fangmeier, C.; Gonzalez Suarez, R.; Kamalieddin, R.; Keller, J.; Knowlton, D.; Kravchenko, I.; Meier, F.; Monroy, J.; Ratnikov, F.; Siado, J. E.; Snow, G. R.; Alyari, M.; Dolen, J.; George, J.; Godshalk, A.; Harrington, C.; Iashvili, I.; Kaisen, J.; Kharchilava, A.; Kumar, A.; Rappoccio, S.; Roozbahani, B.; Alverson, G.; Barberis, E.; Baumgartel, D.; Chasco, M.; Hortiangtham, A.; Massironi, A.; Morse, D. M.; Nash, D.; Orimoto, T.; Teixeira de Lima, R.; Trocino, D.; Wang, R.-J.; Wood, D.; Zhang, J.; Hahn, K. A.; Kubik, A.; Mucia, N.; Odell, N.; Pollack, B.; Pozdnyakov, A.; Schmitt, M.; Stoynev, S.; Sung, K.; Trovato, M.; Velasco, M.; Brinkerhoff, A.; Dev, N.; Hildreth, M.; Jessop, C.; Karmgard, D. J.; Kellams, N.; Lannon, K.; Lynch, S.; Marinelli, N.; Meng, F.; Mueller, C.; Musienko, Y.; Pearson, T.; Planer, M.; Reinsvold, A.; Ruchti, R.; Smith, G.; Taroni, S.; Valls, N.; Wayne, M.; Wolf, M.; Woodard, A.; Antonelli, L.; Brinson, J.; Bylsma, B.; Durkin, L. S.; Flowers, S.; Hart, A.; Hill, C.; Hughes, R.; Ji, W.; Kotov, K.; Ling, T. Y.; Liu, B.; Luo, W.; Puigh, D.; Rodenburg, M.; Winer, B. L.; Wulsin, H. W.; Driga, O.; Elmer, P.; Hardenbrook, J.; Hebda, P.; Koay, S. A.; Lujan, P.; Marlow, D.; Medvedeva, T.; Mooney, M.; Olsen, J.; Palmer, C.; Piroué, P.; Saka, H.; Stickland, D.; Tully, C.; Zuranski, A.; Malik, S.; Barnes, V. E.; Benedetti, D.; Bortoletto, D.; Gutay, L.; Jha, M. K.; Jones, M.; Jung, K.; Miller, D. H.; Neumeister, N.; Primavera, F.; Radburn-Smith, B. C.; Shi, X.; Shipsey, I.; Silvers, D.; Sun, J.; Svyatkovskiy, A.; Wang, F.; Xie, W.; Xu, L.; Parashar, N.; Stupak, J.; Adair, A.; Akgun, B.; Chen, Z.; Ecklund, K. M.; Geurts, F. J. M.; Guilbaud, M.; Li, W.; Michlin, B.; Northup, M.; Padley, B. P.; Redjimi, R.; Roberts, J.; Rorie, J.; Tu, Z.; Zabel, J.; Betchart, B.; Bodek, A.; de Barbaro, P.; Demina, R.; Eshaq, Y.; Ferbel, T.; Galanti, M.; Galanti, M.; Garcia-Bellido, A.; Han, J.; Harel, A.; Hindrichs, O.; Hindrichs, O.; Khukhunaishvili, A.; Petrillo, G.; Tan, P.; Verzetti, M.; Arora, S.; Barker, A.; Chou, J. P.; Contreras-Campana, C.; Contreras-Campana, E.; Duggan, D.; Ferencek, D.; Gershtein, Y.; Gray, R.; Halkiadakis, E.; Hidas, D.; Hughes, E.; Kaplan, S.; Kunnawalkam Elayavalli, R.; Lath, A.; Nash, K.; Panwalkar, S.; Park, M.; Salur, S.; Schnetzer, S.; Sheffield, D.; Somalwar, S.; Stone, R.; Thomas, S.; Thomassen, P.; Walker, M.; Foerster, M.; Riley, G.; Rose, K.; Spanier, S.; York, A.; Bouhali, O.; Castaneda Hernandez, A.; Dalchenko, M.; de Mattia, M.; Delgado, A.; Dildick, S.; Dildick, S.; Eusebi, R.; Gilmore, J.; Kamon, T.; Krutelyov, V.; Krutelyov, V.; Mueller, R.; Osipenkov, I.; Pakhotin, Y.; Patel, R.; Patel, R.; Perloff, A.; Rose, A.; Safonov, A.; Tatarinov, A.; Ulmer, K. A.; Akchurin, N.; Cowden, C.; Damgov, J.; Dragoiu, C.; Dudero, P. R.; Faulkner, J.; Kunori, S.; Lamichhane, K.; Lee, S. W.; Libeiro, T.; Undleeb, S.; Volobouev, I.; Appelt, E.; Delannoy, A. G.; Greene, S.; Gurrola, A.; Janjam, R.; Johns, W.; Maguire, C.; Mao, Y.; Melo, A.; Ni, H.; Sheldon, P.; Snook, B.; Tuo, S.; Velkovska, J.; Xu, Q.; Arenton, M. W.; Cox, B.; Francis, B.; Goodell, J.; Hirosky, R.; Ledovskoy, A.; Li, H.; Lin, C.; Neu, C.; Sinthuprasith, T.; Sun, X.; Wang, Y.; Wolfe, E.; Wood, J.; Xia, F.; Clarke, C.; Harr, R.; Karchin, P. E.; Kottachchi Kankanamge Don, C.; Lamichhane, P.; Sturdy, J.; Belknap, D. A.; Carlsmith, D.; Cepeda, M.; Dasu, S.; Dodd, L.; Duric, S.; Gomber, B.; Grothe, M.; Hall-Wilton, R.; Herndon, M.; Hervé, A.; Klabbers, P.; Lanaro, A.; Levine, A.; Long, K.; Loveless, R.; Mohapatra, A.; Ojalvo, I.; Perry, T.; Pierro, G. A.; Polese, G.; Ruggles, T.; Sarangi, T.; Savin, A.; Sharma, A.; Smith, N.; Smith, W. H.; Taylor, D.; Woods, N.; Collaboration, [Authorinst]The Cms

    2016-07-01

    Jet multiplicity distributions in top quark pair ({t}{overline{t}}) events are measured in pp collisions at a centre-of-mass energy of 8 TeV with the CMS detector at the LHC using a data set corresponding to an integrated luminosity of 19.7 {fb}^ {-1}. The measurement is performed in the dilepton decay channels (e^+e^-, μ^+ μ^-, and e^{±} μ^{∓}). The absolute and normalized differential cross sections for {t}overline{t} production are measured as a function of the jet multiplicity in the event for different jet transverse momentum thresholds and the kinematic properties of the leading additional jets. The differential {t overline{t} b} and {t overline{t} b overline{b}} cross sections are presented for the first time as a function of the kinematic properties of the leading additional b jets. Furthermore, the fraction of events without additional jets above a threshold is measured as a function of the transverse momenta of the leading additional jets and the scalar sum of the transverse momenta of all additional jets. The data are compared and found to be consistent with predictions from several perturbative quantum chromodynamics event generators and a next-to-leading order calculation.

  20. Measurement of $$\\mathrm{ t \\bar{t} } $$ production with additional jet activity, including b quark jets, in the dilepton decay channel using pp collisions at $$\\sqrt{s} =$$ 8 TeV

    DOE PAGES

    Khachatryan, Vardan

    2016-07-07

    Jet multiplicity distributions in top quark pair (tt-bar) events are measured in pp collisions at a centre-of-mass energy of 8 TeV with the CMS detector at the LHC using a data set corresponding to an integrated luminosity of 19.7 fb-1. The measurement is performed in the dilepton decay channels (e+e-,μ+μ- and e±μ∓). Furthermore, the absolute and normalized differential cross sections for tt-bar production are measured as a function of the jet multiplicity in the event for different jet transverse momentum thresholds and the kinematic properties of the leading additional jets. The differential tt-barb and tt-barbb-bar cross sections are presented formore » the first time as a function of the kinematic properties of the leading additional b jets. Furthermore, the fraction of events without additional jets above a threshold is measured as a function of the transverse momenta of the leading additional jets and the scalar sum of the transverse momenta of all additional jets. Finally, the data are compared and found to be consistent with predictions from several perturbative quantum chromodynamics event generators and a next-to-leading ordercalculation.« less

  1. The Application of Quasi-Mean-Element-Method to LEO under Additional Perturbation due to Change of Coordinate System

    NASA Astrophysics Data System (ADS)

    Tang, Jing-shi; Liu, Lin

    2010-10-01

    The perturbation caused by the oscillation of Earth's equator plane must be taken into account when working on the motion of satellite on a low Earth orbit (LEO) in the geocentric celestial coordinate system. Since 1960 s, an intermediate orbit coordinate system using true equator and mean equinox (TEME) is introduced. It effectively solves the problem and has been widely used in various applications till today. But this traditional reference frame is purely conceptual and has always been a headache when performing the transition between these systems especially for those who are unfamiliar with celestial frames. As proved in a previous paper, it is possible to avoid the intermediate TEME frame, and conversions between osculating elements and mean elements can be completed in a consistent geocentric celestial coordinate system where only short-period terms are required. In this paper, after including the improved secular and long-period terms, the quasi-mean-element-method is available to predict the orbit analytically, reaching the accuracy of 10 -6 in Earth's radius. And all these can be done in the same celestial frame. The results suggest that the celestial coordinate system (J2000.0 nowadays) can be used throughout any applications without having to introduce TEME system as intermediate frame any more.

  2. Tantalum trabecular metal - addition of human skeletal cells to enhance bone implant interface strength and clinical application.

    PubMed

    Smith, J O; Sengers, B G; Aarvold, A; Tayton, E R; Dunlop, D G; Oreffo, R O C

    2014-04-01

    The osteo-regenerative properties of allograft have recently been enhanced by addition of autogenous human bone marrow stromal cells (HBMSCs). Limitations in the use of allograft have prompted the investigation of tantalum trabecular metal (TTM) as a potential alternative. TTM is already in widespread orthopaedic use, although in applications where there is poor initial stability, or when TTM is used in conjunction with bone grafting, initial implant loading may need to be limited. The aim of this study was to evaluate the osteo-regenerative potential of TTM with HBMSCs, in direct comparison to human allograft and autograft. HBMSCs were cultured on blocks of TTM, allograft or autograft in basal and osteogenic media. Molecular profiling, confocal and scanning electron microscopy (SEM) and biochemical assays were used to characterize cell adherence, proliferation and phenotype. Mechanical testing was used to define the tensile characteristics of the constructs. HBMSCs displayed adherence and proliferation throughout TTM, evidenced by immunocytochemistry and SEM, with significant cellular ingrowth and matrix production through TTM. In contrast to cells cultured with allograft, cell proliferation assays showed significantly higher activity with TTM (p < 0.001), although molecular profiling confirmed no significant difference in expression of osteogenic genes. In contrast to acellular constructs, mechanical testing of cell-TTM constructs showed enhanced tensile characteristics, which compared favourably to cell-allograft constructs. These studies demonstrated the ability of TTM to support HBMSC growth and osteogenic differentiation comparable to allograft. Thus, TTM represents an alternative to allograft for osteo-regenerative strategies, extending its clinical applications as a substitute for allograft.

  3. Exploration and implementation for the construction of the quaternary teaching system of medical genetics including teaching, practice, research and clinical application.

    PubMed

    Fengjuan, Zhou; Wenmei, Xie; Qiang, Wang; Xiaorong, Zhao

    2015-09-01

    Medical genetics, the connection between basic and clinical medicine, is a subject with strong applicability and plays important role in modern medical education system. Based on years of teaching experience and during the construction of state-level top quality course, our teaching team has established the quaternary teaching system of medical genetics which includes teaching, practice, research and clinical application. The four elements of the system interpenetrate, complement and reinforce each other. Specifically, classroom teaching is the basics which is further complemented by social practice, improved by research and promoted by clinical application. The quaternary teaching system provides a feasible way to integrate theoretical and clinical courses. After years of implementation, the teaching system has got great effects on the obvious improvement of research ability, social reputation and clinical service capacities of the research team.

  4. Development of Additive Construction Technologies for Application to Development of Lunar/Martian Surface Structures Using In-Situ Materials

    NASA Technical Reports Server (NTRS)

    Werkheiser, Niki J.; Fiske, Michael R.; Edmunson, Jennifer E.; Khoshnevis, Berokh

    2015-01-01

    For long-duration missions on other planetary bodies, the use of in situ materials will become increasingly critical. As human presence on these bodies expands, so must the breadth of the structures required to accommodate them including habitats, laboratories, berms, radiation shielding for natural radiation and surface reactors, garages, solar storm shelters, greenhouses, etc. Planetary surface structure manufacturing and assembly technologies that incorporate in situ resources provide options for autonomous, affordable, pre-positioned environments with radiation shielding features and protection from micrometeorites, exhaust plume debris, and other hazards. The ability to use in-situ materials to construct these structures will provide a benefit in the reduction of up-mass that would otherwise make long-term Moon or Mars structures cost prohibitive. The ability to fabricate structures in situ brings with it the ability to repair these structures, which allows for the self-sufficiency and sustainability necessary for long-duration habitation. Previously, under the auspices of the MSFC In-Situ Fabrication and Repair (ISFR) project and more recently, under the jointly-managed MSFC/KSC Additive Construction with Mobile Emplacement (ACME) project, the MSFC Surface Structures Group has been developing materials and construction technologies to support future planetary habitats with in-situ resources. One such additive construction technology is known as Contour Crafting. This paper presents the results to date of these efforts, including development of novel nozzle concepts for advanced layer deposition using this process. Conceived initially for rapid development of cementitious structures on Earth, it also lends itself exceptionally well to the automated fabrication of planetary surface structures using minimally processed regolith as aggregate, and binders developed from in situ materials as well. This process has been used successfully in the fabrication of

  5. Performance of supercritical CO{sub 2} Brayton cycle with additive gases at varying critical points for SFR application

    SciTech Connect

    Jeong, W. S.; Jeong, Y. H.

    2012-07-01

    The supercritical carbon dioxide Brayton cycle (S-CO{sub 2} cycle) has received attention as alternative to the energy conversion system for a Sodium-cooled Fast Reactor (SFR). The high cycle efficiency of S-CO{sub 2} cycle is attributed to significantly reduced compressor work. This is because the compressor operates like a pump in the vicinity of CO{sub 2} critical point. To make use of this feature, the minimum cycle operating range of S-CO{sub 2} cycle, which is the main compressor inlet condition, should be located close to the critical point of CO{sub 2}. This translated into that the critical point of CO{sub 2} is the limitation of the lowest cycle condition of S-CO{sub 2} cycles. To increase the flexibility and broaden the applicability of the cycle, changing the critical point of CO{sub 2} by mixing additive gases could be adopted. An increase in the efficiency of the S-CO{sub 2} cycle could be achieved by decreasing critical point of CO{sub 2}. In addition, increasing critical point of CO{sub 2} could be utilized to obtain improved cycle performances at ascending heat sink temperature of hot arid areas. Due to the rapid fluctuations of thermo-physical properties of gas mixtures near the critical point, an in-house cycle analysis code coupled to NIST property database was developed. Several gases were selected as potential additives through the screening process for thermal stability and chemical interaction with sodium. By using the developed cycle code, optimized cycles of each gas mixture were compared with the reference case of S-CO{sub 2} cycle. For decreased critical temperatures, CO{sub 2}-Xe and CO{sub 2}-Kr showed an increase in the total cycle efficiency. At increasing critical temperatures, the performance of CO{sub 2}-H{sub 2}S and CO{sub 2}-cyclohexane is superior to S-CO{sub 2}cycle when the compressor inlet temperature is above the critical temperature of CO{sub 2}. (authors)

  6. Wavefront holoscopy: application of digital in-line holography for the inspection of engraved marks in progressive addition lenses.

    PubMed

    Perucho, Beatriz; Micó, Vicente

    2014-01-01

    Progressive addition lenses (PALs) are engraved with permanent marks at standardized locations in order to guarantee correct centering and alignment throughout the manufacturing and mounting processes. Out of the production line, engraved marks provide useful information about the PAL as well as act as locator marks to re-ink again the removable marks. Even though those marks should be visible by simple visual inspection with the naked eye, engraving marks are often faint and weak, obscured by scratches, and partially occluded and difficult to recognize on tinted or antireflection-coated lenses. Here, we present an extremely simple optical device (named as wavefront holoscope) for visualization and characterization of permanent marks in PAL based on digital in-line holography. Essentially, a point source of coherent light illuminates the engraved mark placed just before a CCD camera that records a classical Gabor in-line hologram. The recorded hologram is then digitally processed to provide a set of high-contrast images of the engraved marks. Experimental results are presented showing the applicability of the proposed method as a new ophthalmic instrument for visualization and characterization of engraved marks in PALs. PMID:24449144

  7. 20 CFR 670.410 - Are there additional factors which are considered in selecting an eligible applicant for enrollment?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... applicant is not on probation, parole, under a suspended sentence or under the supervision of any agency as... in writing that it will approve of the applicant's release from its supervision and that...

  8. Verification of a New Biocompatible Single-Use Film Formulation with Optimized Additive Content for Multiple Bioprocess Applications

    PubMed Central

    Jurkiewicz, Elke; Husemann, Ute; Greller, Gerhard; Barbaroux, Magali; Fenge, Christel

    2014-01-01

    Single-use bioprocessing bags and bioreactors gained significant importance in the industry as they offer a number of advantages over traditional stainless steel solutions. However, there is continued concern that the plastic materials might release potentially toxic substances negatively impacting cell growth and product titers, or even compromise drug safety when using single-use bags for intermediate or drug substance storage. In this study, we have focused on the in vitro detection of potentially cytotoxic leachables originating from the recently developed new polyethylene (PE) multilayer film called S80. This new film was developed to guarantee biocompatibility for multiple bioprocess applications, for example, storage of process fluids, mixing, and cell culture bioreactors. For this purpose, we examined a protein-free cell culture medium that had been used to extract leachables from freshly gamma-irradiated sample bags in a standardized cell culture assay. We investigated sample bags from films generated to establish the operating ranges of the film extrusion process. Further, we studied sample bags of different age after gamma-irradiation and finally, we performed extended media extraction trials at cold room conditions using sample bags. In contrast to a nonoptimized film formulation, our data demonstrate no cytotoxic effect of the S80 polymer film formulation under any of the investigated conditions. The S80 film formulation is based on an optimized PE polymer composition and additive package. Full traceability alongside specifications and controls of all critical raw materials, and process controls of the manufacturing process, that is, film extrusion and gamma-irradiation, have been established to ensure lot-to-lot consistency. © 2014 American Institute of Chemical Engineers Biotechnol. Prog., 30:1171–1176, 2014 PMID:24850537

  9. Influence of Si addition on the microstructure and mechanical properties of Ti-35Nb alloy for applications in orthopedic implants.

    PubMed

    Tavares, A M G; Ramos, W S; de Blas, J C G; Lopes, E S N; Caram, R; Batista, W W; Souza, S A

    2015-11-01

    In the development of new materials for orthopedic implants, special attention has been given to Ti alloys that show biocompatible alloy elements and that are capable of reducing the elastic modulus. Accordingly, Ti-Nb-Si alloys show great potential for application. Thus, this is a study on the microstructures and properties of Ti-35Nb-xSi alloys (x=0, 0.15, 0.35 and 0.55) (wt%) which were thermally treated and cooled under the following conditions: furnace cooling (FC), air cooling (AC), and water quenching (WQ). The results showed that Si addition is effective to reduce the density of omega precipitates making beta more stable, and to produce grain refinement. Silicides, referred as (Ti,Nb)3Si, were formed for alloys containing 0.55% Si, and its formation presumably occurred during the heating at 1000°C. In all cooling conditions, the hardness values increased with the increasing of Si content, as a result from the strong Si solid solution strengthening effect, while the elastic modulus underwent a continuous reduction due to the reduction of omega precipitates in beta matrix. Lower elastic moduli were observed in water-quenched alloys, which concentration of 0.15% Si was more effective in their reduction, with value around 65 GPa. Regarding Ti-35Nb-xSi alloys (x=0, 0.15 and 0.35), the "double yield point" phenomenon, which is typical of alloys with shape memory effect, was observed. The increase in Si concentration also produced an increase from 382 MPa to 540 MPa in the alloys' mechanical strength. Ti-35Nb-0.55Si alloy, however, showed brittle mechanical behavior which was related to the presence of silicides at the grain boundary.

  10. An oxidant- and solvent-stable protease produced by Bacillus cereus SV1: application in the deproteinization of shrimp wastes and as a laundry detergent additive.

    PubMed

    Manni, Laila; Jellouli, Kemel; Ghorbel-Bellaaj, Olfa; Agrebi, Rym; Haddar, Anissa; Sellami-Kamoun, Alya; Nasri, Moncef

    2010-04-01

    The current increase in amount of shrimp wastes produced by the shrimp industry has led to the need in finding new methods for shrimp wastes disposal. In this study, an extracellular organic solvent- and oxidant-stable metalloprotease was produced by Bacillus cereus SV1. Maximum protease activity (5,900 U/mL) was obtained when the strain was grown in medium containing 40 g/L shrimp wastes powder as a sole carbon source. The optimum pH, optimum temperature, pH stability, and thermal stability of the crude enzyme preparation were pH 8.0, 60 degrees C, pH 6-9.5, and <55 degrees C, respectively. The crude protease was extremely stable toward several organic solvents. No loss of activity was observed even after 60 days of incubation at 30 degrees C in the presence of 50% (v/v) dimethyl sulfoxide and ethyl ether; the enzyme retained more than 70% of its original activity in the presence of ethanol and N,N-dimethylformamide. The protease showed high stability toward anionic (SDS) and non-ionic (Tween 80, Tween 20, and Triton X-100) surfactants. Interestingly, the activity of the enzyme was significantly enhanced by oxidizing agents. In addition, the enzyme showed excellent compatibility with some commercial liquid detergents. The protease of B. cereus SV1, produced under the optimal culture conditions, was tested for shrimp waste deproteinization in the preparation of chitin. The protein removal with a ratio E/S of 20 was about 88%. The novelties of the SV1 protease include its high stability to organic solvents and surfactants. These unique properties make it an ideal choice for application in detergent formulations and enzymatic peptide synthesis. In addition, the enzyme may find potential applications in the deproteinization of shrimp wastes to produce chitin.

  11. 34 CFR 660.32 - What additional selection criteria does the Secretary use for an application for a research...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... use for an application for a research project, a survey, or a study? 660.32 Section 660.32 Education... evaluates an application for a research project, study, or survey on the basis of the criteria in this..., DEPARTMENT OF EDUCATION THE INTERNATIONAL RESEARCH AND STUDIES PROGRAM How Does the Secretary Make a...

  12. 34 CFR 660.32 - What additional selection criteria does the Secretary use for an application for a research...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... use for an application for a research project, a survey, or a study? 660.32 Section 660.32 Education... evaluates an application for a research project, study, or survey on the basis of the criteria in this..., DEPARTMENT OF EDUCATION THE INTERNATIONAL RESEARCH AND STUDIES PROGRAM How Does the Secretary Make a...

  13. 34 CFR 660.32 - What additional selection criteria does the Secretary use for an application for a research...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... use for an application for a research project, a survey, or a study? 660.32 Section 660.32 Education... evaluates an application for a research project, study, or survey on the basis of the criteria in this..., DEPARTMENT OF EDUCATION THE INTERNATIONAL RESEARCH AND STUDIES PROGRAM How Does the Secretary Make a...

  14. 34 CFR 350.55 - What are the additional considerations for selecting Field-Initiated Project applications for...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., DEPARTMENT OF EDUCATION DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM How Does the... Field-Initiated Project applications for funding? 350.55 Section 350.55 Education Regulations of the... Project applications for funding? (a) The Secretary reserves funds to support some or all of the...

  15. {sup 13}C chemical shift anisotropies for carbonate ions in cement minerals and the use of {sup 13}C, {sup 27}Al and {sup 29}Si MAS NMR in studies of Portland cement including limestone additions

    SciTech Connect

    Sevelsted, Tine F.; Herfort, Duncan

    2013-10-15

    {sup 13}C isotropic chemical shifts and chemical shift anisotropy parameters have been determined for a number of inorganic carbonates relevant in cement chemistry from slow-speed {sup 13}C MAS or {sup 13}C({sup 1}H) CP/MAS NMR spectra (9.4 T or 14.1 T) for {sup 13}C in natural abundance. The variation in the {sup 13}C chemical shift parameters is relatively small, raising some doubts that different carbonate species in Portland cement-based materials may not be sufficiently resolved in {sup 13}C MAS NMR spectra. However, it is shown that by combining {sup 13}C MAS and {sup 13}C({sup 1}H) CP/MAS NMR carbonate anions in anhydrous and hydrated phases can be distinguished, thereby providing valuable information about the reactivity of limestone in cement blends. This is illustrated for three cement pastes prepared from an ordinary Portland cement, including 0, 16, and 25 wt.% limestone, and following the hydration for up to one year. For these blends {sup 29}Si MAS NMR reveals that the limestone filler accelerates the hydration for alite and also results in a smaller fraction of tetrahedrally coordinated Al incorporated in the C-S-H phase. The latter result is more clearly observed in {sup 27}Al MAS NMR spectra of the cement–limestone blends and suggests that dissolved aluminate species in the cement–limestone blends readily react with carbonate ions from the limestone filler, forming calcium monocarboaluminate hydrate. -- Highlights: •{sup 13}C chemical shift anisotropies for inorganic carbonates from {sup 13}C MAS NMR. •Narrow {sup 13}C NMR chemical shift range (163–171 ppm) for inorganic carbonates. •Anhydrous and hydrated carbonate species by {sup 13}C MAS and {sup 13}C({sup 1}H) CP/MAS NMR. •Limestone accelerates the hydration for alite in Portland – limestone cements. •Limestone reduces the amount of aluminium incorporated in the C-S-H phase.

  16. German database on the occurrence of food additives: application for intake estimation of five food colours for toddlers and children.

    PubMed

    Diouf, Friederike; Berg, Katharina; Ptok, Sebastian; Lindtner, Oliver; Heinemeyer, Gerhard; Heseker, Helmut

    2014-01-01

    To get a more realistic estimation of food additive intake for toddlers and children, a German database on the occurrence of food additives was created. It uses consumption data of two recent national nutrition surveys for toddlers and children in combination with qualitative information of food additive occurrence in the consumed food. The information on food additive occurrence is based on food labelling. A categorisation system was developed according to regulations to classify the foods consumed and to identify possible food additive use in the food groups. Two natural (E120, E160b) and three artificial food colours (E110, E124, E129) were chosen for an assessment of food additive intake. The percentage of food items containing one of the chosen food colours was calculated for every food group and the food groups with most items containing the additive were identified. Intake estimations were performed based on maximum permitted-use levels (MPLs). Firstly, additive use was assumed in all foods consumed (tier 2); and secondly, food additive use was assumed only for those items where labelling confirmed the use and for all foods with no labelling available (tier 2b). Intake estimations were then compared with the ADI. Most food items with at least one of the food colours were found in the food groups confectionary, desserts, fermented milk products, flavoured drinks and breakfast cereals. The tier 2b approach provided more realistic estimations, which were always below those of the tier 2 approach and below the ADI for mean exposure. Exposure for high-level consumers exceeded the ADI for two of the food additives in tier 2b. Keeping in mind that the database is only mirroring the current situation, it provides a good possibility to refine the estimation of food additive intake for toddlers and children in Germany. PMID:24229358

  17. German database on the occurrence of food additives: application for intake estimation of five food colours for toddlers and children.

    PubMed

    Diouf, Friederike; Berg, Katharina; Ptok, Sebastian; Lindtner, Oliver; Heinemeyer, Gerhard; Heseker, Helmut

    2014-01-01

    To get a more realistic estimation of food additive intake for toddlers and children, a German database on the occurrence of food additives was created. It uses consumption data of two recent national nutrition surveys for toddlers and children in combination with qualitative information of food additive occurrence in the consumed food. The information on food additive occurrence is based on food labelling. A categorisation system was developed according to regulations to classify the foods consumed and to identify possible food additive use in the food groups. Two natural (E120, E160b) and three artificial food colours (E110, E124, E129) were chosen for an assessment of food additive intake. The percentage of food items containing one of the chosen food colours was calculated for every food group and the food groups with most items containing the additive were identified. Intake estimations were performed based on maximum permitted-use levels (MPLs). Firstly, additive use was assumed in all foods consumed (tier 2); and secondly, food additive use was assumed only for those items where labelling confirmed the use and for all foods with no labelling available (tier 2b). Intake estimations were then compared with the ADI. Most food items with at least one of the food colours were found in the food groups confectionary, desserts, fermented milk products, flavoured drinks and breakfast cereals. The tier 2b approach provided more realistic estimations, which were always below those of the tier 2 approach and below the ADI for mean exposure. Exposure for high-level consumers exceeded the ADI for two of the food additives in tier 2b. Keeping in mind that the database is only mirroring the current situation, it provides a good possibility to refine the estimation of food additive intake for toddlers and children in Germany.

  18. Standard addition flow method for potentiometric measurements at low concentration levels: application to the determination of fluoride in food samples.

    PubMed

    Galvis-Sánchez, Andrea C; Santos, João Rodrigo; Rangel, António O S S

    2015-02-01

    A standard addition method was implemented by using a flow manifold able to perform automatically multiple standard additions and in-line sample treatment. This analytical strategy was based on the in-line mixing of sample and standard addition solutions, using a merging zone approach. The flow system aimed to exploit the standard addition method to quantify the target analyte particularly in cases where the analyte concentration in the matrix is below the lower limit of linear response of the detector. The feasibility of the proposed flow configuration was assessed through the potentiometric determination of fluoride in sea salts of different origins and different types of coffee infusions. The limit of quantification of the proposed manifold was 5×10(-6) mol L(-1), 10-fold lower than the lower limit of linear response of the potentiometric detector used. A determination rate of 8 samples h(-1) was achieved considering an experimental procedure based on three standard additions per sample. The main advantage of the proposed strategy is the simple approach to perform multiple standard additions, which can be implemented with other ion selective electrodes, especially in cases when the primary ion is below the lower limit of linear response of the detector.

  19. Food additives

    PubMed Central

    Spencer, Michael

    1974-01-01

    Food additives are discussed from the food technology point of view. The reasons for their use are summarized: (1) to protect food from chemical and microbiological attack; (2) to even out seasonal supplies; (3) to improve their eating quality; (4) to improve their nutritional value. The various types of food additives are considered, e.g. colours, flavours, emulsifiers, bread and flour additives, preservatives, and nutritional additives. The paper concludes with consideration of those circumstances in which the use of additives is (a) justified and (b) unjustified. PMID:4467857

  20. Time optimal control of an additional food provided predator-prey system with applications to pest management and biological conservation.

    PubMed

    Srinivasu, P D N; Prasad, B S R V

    2010-04-01

    Use of additional food has been widely recognized by experimental scientists as one of the important tools for biological control such as species conservation and pest management. The quality and quantity of additional food supplied to the predators is known to play a vital role in the controllability of the system. The present study is continuation of a previous work that highlights the importance of quality and quantity of the additional food in the dynamics of a predator-prey system in the context of biological control. In this article the controllability of the predator-prey system is analyzed by considering inverse of quality of the additional food as the control variable. Control strategies are offered to steer the system from a given initial state to a required terminal state in a minimum time by formulating Mayer problem of optimal control. It is observed that an optimal strategy is a combination of bang-bang controls and could involve multiple switches. Properties of optimal paths are derived using necessary conditions for Mayer problem. In the light of the results evolved in this work it is possible to eradicate the prey from the eco-system in the minimum time by providing the predator with high quality additional food, which is relevant in the pest management. In the perspective of biological conservation this study highlights the possibilities to drive the state to an admissible interior equilibrium (irrespective of its stability nature) of the system in a minimum time.

  1. Addition theorems for Slater-type orbitals and their application to multicenter multielectron integrals of central and noncentral interaction potentials.

    PubMed

    Guseinov, Israfil

    2003-06-01

    By the use of complete orthonormal sets of psi(alpha)-ETOs (alpha=1, 0, m1, m2,...) introduced by the author, new addition theorems are derived for STOs and arbitrary central and noncentral interaction potentials (CIPs and NCIPs). The expansion coefficients in these addition theorems are expressed through the Gaunt and Gegenbauer coefficients. Using the addition theorems obtained for STOs and potentials, general formulae in terms of three-center overlap integrals are established for the multicenter t-electron integrals of CIPs and NCIPs that arise in the solution of the N-electron atomic and molecular problem (2hthN) when a Hylleraas approximation in Hartree-Fock-Roothaan theory is employed. With the help of expansion formulae for translation of STOs, the three-center overlap integrals are expressed through the two-center overlap integrals. The formulae obtained are valid for arbitrary quantum numbers, screening constants and location of orbitals. PMID:12750966

  2. 34 CFR 660.32 - What additional selection criteria does the Secretary use for an application for a research...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... section. (a) Need for the project. The Secretary reviews each application for information that shows— (1... proposed project will provide information about the present and future needs of the United States for study in foreign language and other international fields. (b) Usefulness of expected results. The...

  3. 20 CFR 670.410 - Are there additional factors which are considered in selecting an eligible applicant for enrollment?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., as described in procedures issued by the Secretary; (d) The applicant passes a background check conducted according to procedures established by the Secretary. The background check must find that the... for enrollment, only if: (a) A determination is made, based on information relating to the...

  4. 20 CFR 670.410 - Are there additional factors which are considered in selecting an eligible applicant for enrollment?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., as described in procedures issued by the Secretary; (d) The applicant passes a background check conducted according to procedures established by the Secretary. The background check must find that the... for enrollment, only if: (a) A determination is made, based on information relating to the...

  5. 20 CFR 670.410 - Are there additional factors which are considered in selecting an eligible applicant for enrollment?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., as described in procedures issued by the Secretary; (d) The applicant passes a background check conducted according to procedures established by the Secretary. The background check must find that the... for enrollment, only if: (a) A determination is made, based on information relating to the...

  6. 20 CFR 670.410 - Are there additional factors which are considered in selecting an eligible applicant for enrollment?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., as described in procedures issued by the Secretary; (d) The applicant passes a background check conducted according to procedures established by the Secretary. The background check must find that the..., only if: (a) A determination is made, based on information relating to the background, needs...

  7. 34 CFR 611.24 - What additional selection criteria are used for a full application that proposes teacher...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... commitment to recruit, support and prepare additional well-qualified new teachers for high-need schools; (2) Appropriate academic and student support services; and (3) A comprehensive strategy for addressing shortages... impact of the project on high-need LEAs and high-need schools based upon— (1) The amount of...

  8. 20 CFR 641.210 - What services, in addition to the applicable core services, must SCSEP grantees and sub...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... sub-recipients provide through the One-Stop delivery system? In addition to providing core services, as defined at 20 CFR 662.240 of the WIA regulations, SCSEP grantees and sub-recipients must make... core services, must SCSEP grantees and sub-recipients provide through the One-Stop delivery system?...

  9. 20 CFR 641.210 - What services, in addition to the applicable core services, must SCSEP grantees and sub...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... sub-recipients provide through the One-Stop delivery system? In addition to providing core services, as defined at 20 CFR 662.240 of the WIA regulations, SCSEP grantees and sub-recipients must make... core services, must SCSEP grantees and sub-recipients provide through the One-Stop delivery system?...

  10. 20 CFR 641.210 - What services, in addition to the applicable core services, must SCSEP grantees and sub...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... sub-recipients provide through the One-Stop delivery system? In addition to providing core services, as defined at 20 CFR 662.240 of the WIA regulations, SCSEP grantees and sub-recipients must make... core services, must SCSEP grantees and sub-recipients provide through the One-Stop delivery system?...

  11. 20 CFR 641.210 - What services, in addition to the applicable core services, must SCSEP grantees and sub...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... sub-recipients provide through the One-Stop delivery system? In addition to providing core services, as defined at 20 CFR 662.240 of the WIA regulations, SCSEP grantees and sub-recipients must make... core services, must SCSEP grantees and sub-recipients provide through the One-Stop delivery system?...

  12. 34 CFR 611.12 - What additional selection criteria are used for an application proposing teacher recruitment...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... selection criteria: (a) In addition to the elements contained in § 611.11(a) (Quality of project design), the Secretary considers the extent to which the project addresses— (1) Systemic changes in the ways... elements contained in § 611.11(c) (Quality of resources), the Secretary considers the impact of the...

  13. 34 CFR 611.12 - What additional selection criteria are used for an application proposing teacher recruitment...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... selection criteria: (a) In addition to the elements contained in § 611.11(a) (Quality of project design), the Secretary considers the extent to which the project addresses— (1) Systemic changes in the ways... elements contained in § 611.11(c) (Quality of resources), the Secretary considers the impact of the...

  14. Additive Manufacturing by selective laser melting the realizer desktop machine and its application for the dental industry

    NASA Astrophysics Data System (ADS)

    Gebhardt, Andreas; Schmidt, Frank-Michael; Hötter, Jan-Steffen; Sokalla, Wolfgang; Sokalla, Patrick

    Additive Manufacturing of metal parts by Selective Laser Melting has become a powerful tool for the direct manufacturing of complex parts mainly for the aerospace and medical industry. With the introduction of its desktop machine, Realizer targeted the dental market. The contribution describes the special features of the machine, discusses details of the process and shows manufacturing results focused on metal dental devices.

  15. Behavior and Distribution of Heavy Metals Including Rare Earth Elements, Thorium, and Uranium in Sludge from Industry Water Treatment Plant and Recovery Method of Metals by Biosurfactants Application

    PubMed Central

    Gao, Lidi; Kano, Naoki; Sato, Yuichi; Li, Chong; Zhang, Shuang; Imaizumi, Hiroshi

    2012-01-01

    In order to investigate the behavior, distribution, and characteristics of heavy metals including rare earth elements (REEs), thorium (Th), and uranium (U) in sludge, the total and fractional concentrations of these elements in sludge collected from an industry water treatment plant were determined and compared with those in natural soil. In addition, the removal/recovery process of heavy metals (Pb, Cr, and Ni) from the polluted sludge was studied with biosurfactant (saponin and sophorolipid) elution by batch and column experiments to evaluate the efficiency of biosurfactant for the removal of heavy metals. Consequently, the following matters have been largely clarified. (1) Heavy metallic elements in sludge have generally larger concentrations and exist as more unstable fraction than those in natural soil. (2) Nonionic saponin including carboxyl group is more efficient than sophorolipid for the removal of heavy metals in polluted sludge. Saponin has selectivity for the mobilization of heavy metals and mainly reacts with heavy metals in F3 (the fraction bound to carbonates) and F5 (the fraction bound to Fe-Mn oxides). (3) The recovery efficiency of heavy metals (Pb, Ni, and Cr) reached about 90–100% using a precipitation method with alkaline solution. PMID:22693485

  16. Behavior and distribution of heavy metals including rare Earth elements, thorium, and uranium in sludge from industry water treatment plant and recovery method of metals by biosurfactants application.

    PubMed

    Gao, Lidi; Kano, Naoki; Sato, Yuichi; Li, Chong; Zhang, Shuang; Imaizumi, Hiroshi

    2012-01-01

    In order to investigate the behavior, distribution, and characteristics of heavy metals including rare earth elements (REEs), thorium (Th), and uranium (U) in sludge, the total and fractional concentrations of these elements in sludge collected from an industry water treatment plant were determined and compared with those in natural soil. In addition, the removal/recovery process of heavy metals (Pb, Cr, and Ni) from the polluted sludge was studied with biosurfactant (saponin and sophorolipid) elution by batch and column experiments to evaluate the efficiency of biosurfactant for the removal of heavy metals. Consequently, the following matters have been largely clarified. (1) Heavy metallic elements in sludge have generally larger concentrations and exist as more unstable fraction than those in natural soil. (2) Nonionic saponin including carboxyl group is more efficient than sophorolipid for the removal of heavy metals in polluted sludge. Saponin has selectivity for the mobilization of heavy metals and mainly reacts with heavy metals in F3 (the fraction bound to carbonates) and F5 (the fraction bound to Fe-Mn oxides). (3) The recovery efficiency of heavy metals (Pb, Ni, and Cr) reached about 90-100% using a precipitation method with alkaline solution.

  17. An analysis of shock coalescence including three-dimensional effects with application to sonic boom extrapolation. Ph.D. Thesis - George Washington Univ.

    NASA Technical Reports Server (NTRS)

    Darden, C. M.

    1984-01-01

    A method for analyzing shock coalescence which includes three dimensional effects was developed. The method is based on an extension of the axisymmetric solution, with asymmetric effects introduced through an additional set of governing equations, derived by taking the second circumferential derivative of the standard shock equations in the plane of symmetry. The coalescence method is consistent with and has been combined with a nonlinear sonic boom extrapolation program which is based on the method of characteristics. The extrapolation program, is able to extrapolate pressure signatures which include embedded shocks from an initial data line in the plane of symmetry at approximately one body length from the axis of the aircraft to the ground. The axisymmetric shock coalescence solution, the asymmetric shock coalescence solution, the method of incorporating these solutions into the extrapolation program, and the methods used to determine spatial derivatives needed in the coalescence solution are described. Results of the method are shown for a body of revolution at a small, positive angle of attack.

  18. 20 CFR 662.260 - What services, in addition to the applicable core services, are to be provided by One-Stop...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... partner's authorizing laws. The access to these services must be described in the local MOU. 20 CFR part... core services, are to be provided by One-Stop partners through the One-Stop delivery system? 662.260... Responsibilities of Partners § 662.260 What services, in addition to the applicable core services, are to...

  19. Perspectives on Additive Manufacturing

    NASA Astrophysics Data System (ADS)

    Bourell, David L.

    2016-07-01

    Additive manufacturing (AM) has skyrocketed in visibility commercially and in the public sector. This article describes the development of this field from early layered manufacturing approaches of photosculpture, topography, and material deposition. Certain precursors to modern AM processes are also briefly described. The growth of the field over the last 30 years is presented. Included is the standard delineation of AM technologies into seven broad categories. The economics of AM part generation is considered, and the impacts of the economics on application sectors are described. On the basis of current trends, the future outlook will include a convergence of AM fabricators, mass-produced AM fabricators, enabling of topology optimization designs, and specialization in the AM legal arena. Long-term developments with huge impact are organ printing and volume-based printing.

  20. Application of copper nanoparticles as additions to a grinding fluid to increase the quality of grinding of magnetic ceramic materials

    NASA Astrophysics Data System (ADS)

    Krevchik, V. D.; Skryabin, V. A.; Sokolov, A. V.; Men'shova, S. B.; Artemov, I. I.; Prokof'ev, M. V.; Karasev, N. Ya.

    2015-12-01

    The influence of copper nanoparticles in a grinding fluid (GF) used for grinding on the characteristics of the surface layer of ferrite parts and their service properties is studied. Profilograms of the ground surfaces and their roughness are measured. The electromagnetic losses of 10000NN ferrite parts ground in an GF medium with copper nanoparticles are estimated. The use of metal nanoparticles as additions to a grinding fluid is shown to be useful for processing of brittle nonmetallic materials.

  1. Applicability of the DPPH assay for evaluating the antioxidant capacity of food additives - inter-laboratory evaluation study -.

    PubMed

    Shimamura, Tomoko; Sumikura, Yoshihiro; Yamazaki, Takeshi; Tada, Atsuko; Kashiwagi, Takehiro; Ishikawa, Hiroya; Matsui, Toshiro; Sugimoto, Naoki; Akiyama, Hiroshi; Ukeda, Hiroyuki

    2014-01-01

    An inter-laboratory evaluation study was conducted in order to evaluate the antioxidant capacity of food additives by using a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. Four antioxidants used as existing food additives (i.e., tea extract, grape seed extract, enju extract, and d-α-tocopherol) and 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox) were used as analytical samples, and 14 laboratories participated in this study. The repeatability relative standard deviation (RSD(r)) of the IC50 of Trolox, four antioxidants, and the Trolox equivalent antioxidant capacity (TEAC) were 1.8-2.2%, 2.2-2.9%, and 2.1-2.5%, respectively. Thus, the proposed DPPH assay showed good performance within the same laboratory. The reproducibility relative standard deviation (RSD(R)) of IC50 of Trolox, four antioxidants, and TEAC were 4.0-7.9%, 6.0-11%, and 3.7-9.3%, respectively. The RSD(R)/RSD(r) values of TEAC were lower than, or nearly equal to, those of IC50 of the four antioxidants, suggesting that the use of TEAC was effective for reducing the variance among the laboratories. These results showed that the proposed DPPH assay could be used as a standard method to evaluate the antioxidant capacity of food additives.

  2. Calculating slope and ED50 of additive dose-response curves, and application of these tabulated parameter values.

    PubMed

    Pöch, G; Pancheva, S N

    1995-06-01

    Comparing dose-response curves (DRCs) of a compound A in the absence and presence of a fixed dose of an antagonist B is standard in pharmacology and toxicology. When B qualitatively resembles A in its action, it is often useful to construct theoretical DRCs of additive and independent combinations. Theoretical curves are calculated from experimental values by the program ALLFIT, which uses the four parameter logistic equation. DRCs of theoretical, additive DRCs are obtained by using the respective values for slope and ED50, which were taken from tables presented here compiled on the basis of the slope of the DRC of A alone (0.6-14) and of the effect of B alone (1-75%). These tables are unnecessary for the construction of theoretical curves if A acts by an independent mechanism, giving values for slope and ED50 identical to those of the DRC of A alone. Experimental DRCs of antiviral and other effects (the latter taken from data in the literature) are compared with theoretical curves by an F-test analysis provided by ALLFIT. The method can be used successfully for the construction of theoretical curves for additive and independent DRCs and comparison with experimental curves. This comparison may help clarify the mode of interaction of A with B. PMID:7640393

  3. Crystal modification of iron oxide scale by potassium addition and its application to lithium-ion battery anodes

    NASA Astrophysics Data System (ADS)

    Jung, Dong-Won; Han, Sang-Wook; Kong, Byung-Seon; Oh, Eun-Suok

    2013-11-01

    This paper proposes a valuable method to reuse the iron oxide scale (IOS) often produced in the steel industry as an anode active material in lithium-ion batteries (LIBs). The IOS samples are prepared via quenching of carbon steel and simple oxidation at a high temperature with or without sequential treatment by potassium hydroxide. Morphological and physical characterizations confirm the formation of a lamellar structure of orthorhombic KFeO2 with a high degree of crystallinity in the potassium-added IOSs. Additionally, the potassium addition decreases the particle size of the crystals and increases the d-spacing between crystal layers. Electrochemical performance tests show that the discharge capacities of the IOS samples monotonically increased with increasing number of charge/discharge cycles regardless of the existence of potassium. In addition, the rate of increase is larger in the potassium-added IOS samples containing the lamellar KFeO2 structure. Consequently, after prolonged cycling (more than 500 cycles), the potassium-added IOS sample retains a discharge capacity of 1020 mAh g-1 with good cycling stability, while the IOS quenched sample only exhibits a capacity of 956 mAh g-1. This result is attributed to the unique structure of the KFeO2 crystals formed in the potassium-added IOS particles.

  4. Development of additive [11C]CO2 target system in the KOTRON-13 cyclotron and its application for [11C]radiopharmaceutical production

    NASA Astrophysics Data System (ADS)

    Moon, Byung Seok; Lee, Hong Jin; Lee, Won Kyung; Hur, Min Goo; Yang, Seung Dae; Lee, Byung Chul; Kim, Sang Eun

    2015-08-01

    The KOTRON-13 cyclotron, which was developed in South Korea for the production of medical radioisotopes, has the structural limitation of only one beam-output port, restricting the production of the carbon-11 isotope. In the present study, we investigate the design of a switchable target system and develop an effective carbon-11 target in the KOTRON-13 cyclotron, for combination with the fluorine-18 target. The target system was designed by introducing a sliding-type element between the fluorine-18 and carbon-11 targets, a tailor-made C-11 target and its cooling system. For the efficient production of [11C]CO2, the desirable target shape and internal volume were determined by a Stopping and Range of Ions in Matter (SRIM) simulation program, and the target grid was modified to resist the cavity pressure during beam irradiation. We evaluated the [11C]CO2 production while varying the material and thickness of the target foil, oxygen content of the nitrogen gas, and target loading pressure. Using sliding-type equipment including an additional gate valve and a high vacuum in a beam line, the bi-directional conversion between the fluorine-18 and carbon-11 targets was efficient regarding the accurate beam irradiation on both targets. The optimal [11C]CO2 production for 30 min irradiation at 60 μA (86.6 ± 1.7 GBq in the target at EOB) was observed at a thickness of 19 μm with HAVAR® material as a target foil and a target loading pressure of 24 bar with nitrogen plus 300 ppb of oxygen gas. Additionally, the coolant cavity system in the target grid and target chamber is useful to remove the heat transferred to the target body by the internal convection of water and thereby ensure the stability of the [11C]CO2 production under a high beam current. In the application of C-11 labeled radiopharmaceuticals such as [11C]PIB, [11C]DASB, [11C]PBR28, [11C]Methionine and [11C]Clozapine, the radiochemical yields were shown to be 25-38% (decay corrected) with over 166 GBq/μmol of

  5. High Temperature Superconductors: From Delivery to Applications (Presentation from 2011 Ernest Orlando Lawrence Award-winner, Dr. Amit Goyal, and including introduction by Energy Secretary, Dr. Steven Chu)

    SciTech Connect

    Goyal, Amit

    2012-05-22

    Dr. Amit Goyal, a high temperature superconductivity (HTS) researcher at Oak Ridge National Laboratory, was named a 2011 winner of the Department of Energy's Ernest Orlando Lawrence Award honoring U.S. scientists and engineers for exceptional contributions in research and development supporting DOE and its mission. Winner of the award in the inaugural category of Energy Science and Innovation, Dr. Goyal was cited for his work in 'pioneering research and transformative contributions to the field of applied high temperature superconductivity, including fundamental materials science advances and technical innovations enabling large-scale applications of these novel materials.' Following his basic research in grain-to-grain supercurrent transport, Dr. Goyal focused his energy in transitioning this fundamental understanding into cutting-edge technologies. Under OE sponsorship, Dr. Goyal co-invented the Rolling Assisted Bi-Axially Textured Substrate technology (RABiTS) that is used as a substrate for second generation HTS wires. OE support also led to the invention of Structural Single Crystal Faceted Fiber Substrate (SSIFFS) and the 3-D Self Assembly of Nanodot Columns. These inventions and associated R&D resulted in 7 R&D 100 Awards including the 2010 R&D Magazine's Innovator of the Year Award, 3 Federal Laboratory Consortium Excellence in Technology Transfer National Awards, a DOE Energy100 Award and many others. As a world authority on HTS materials, Dr. Goyal has presented OE-sponsored results in more than 150 invited talks, co-authored more than 350 papers and is a fellow of 7 professional societies.

  6. High Temperature Superconductors: From Delivery to Applications (Presentation from 2011 Ernest Orlando Lawrence Award-winner, Dr. Amit Goyal, and including introduction by Energy Secretary, Dr. Steven Chu)

    ScienceCinema

    Goyal, Amit (Oak Ridge National Laboratory)

    2016-07-12

    Dr. Amit Goyal, a high temperature superconductivity (HTS) researcher at Oak Ridge National Laboratory, was named a 2011 winner of the Department of Energy's Ernest Orlando Lawrence Award honoring U.S. scientists and engineers for exceptional contributions in research and development supporting DOE and its mission. Winner of the award in the inaugural category of Energy Science and Innovation, Dr. Goyal was cited for his work in 'pioneering research and transformative contributions to the field of applied high temperature superconductivity, including fundamental materials science advances and technical innovations enabling large-scale applications of these novel materials.' Following his basic research in grain-to-grain supercurrent transport, Dr. Goyal focused his energy in transitioning this fundamental understanding into cutting-edge technologies. Under OE sponsorship, Dr. Goyal co-invented the Rolling Assisted Bi-Axially Textured Substrate technology (RABiTS) that is used as a substrate for second generation HTS wires. OE support also led to the invention of Structural Single Crystal Faceted Fiber Substrate (SSIFFS) and the 3-D Self Assembly of Nanodot Columns. These inventions and associated R&D resulted in 7 R&D 100 Awards including the 2010 R&D Magazine's Innovator of the Year Award, 3 Federal Laboratory Consortium Excellence in Technology Transfer National Awards, a DOE Energy100 Award and many others. As a world authority on HTS materials, Dr. Goyal has presented OE-sponsored results in more than 150 invited talks, co-authored more than 350 papers and is a fellow of 7 professional societies.

  7. Applicability of a carbamate insecticide multiresidue method for determining additional types of pesticides in fruits and vegetables.

    PubMed

    Krause, R T; August, E M

    1983-03-01

    Several fruits and vegetables were fortified at a low (0.02-0.5 ppm) and at a high (0.1-5 ppm) level with pesticides and with a synergist, and recoveries were determined. Analyses were performed by using 3 steps of a multiresidue method for determining N-methylcarbamates in crops: methanol extraction followed by removal of plant co-extractives by solvent partitioning and chromatography with a charcoal-silanized Celite column. Eleven compounds were determined by using a high performance liquid chromatograph equipped with a reverse phase column and a fluorescence detector. Twelve additional compounds were determined by using a gas-liquid chromatograph equipped with a nonpolar packed column and an electron capture or flame photometric detector. Recoveries of 10 pesticides (azinphos ethyl, azinphos methyl, azinphos methyl oxygen analog, carbaryl, carbofuran, naphthalene acetamide, naphthalene acetic acid methyl ester, napropamide, phosalone, and phosalone oxygen analog) and the synergist piperonyl butoxide, which were determined by high performance liquid chromatography, averaged 100% (range 86-117) at the low fortification level and 102% (range 93-115) at the high fortification level. Quantitative recovery of naphthalene acetamide through the method required that an additional portion of eluting solution be passed through the charcoal column. Recoveries of 7 additional pesticides (dimethoate, malathion, methyl parathion, mevinphos, parathion, phorate oxygen analog, and pronamide), which were determined by gas-liquid chromatography (GLC), averaged 108% (range 100-120) at the low fortification level and 107% (range 99-122) at the high fortification level. DDT, diazinon, dieldrin, phorate, and pirimiphos ethyl, which were determined by GLC, were not quantitatively recovered. PMID:6853408

  8. 45 CFR 1351.19 - What additional information should an applicant or grantee have about a Runaway and Homeless...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Homeless Youth Program grants. These include: (1) The provisions of 45 CFR part 74 pertaining to the Administration of Grants; (2) The provisions of 45 CFR part 16, Departmental Grants Appeal Process, and the provisions of Informal Grant Appeal Procedures (Indirect Costs) in volume 45 CFR part 75; (3) The...

  9. 45 CFR 1351.19 - What additional information should an applicant or grantee have about a Runaway and Homeless...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Homeless Youth Program grants. These include: (1) The provisions of 45 CFR part 74 pertaining to the Administration of Grants; (2) The provisions of 45 CFR part 16, Departmental Grants Appeal Process, and the provisions of Informal Grant Appeal Procedures (Indirect Costs) in volume 45 CFR part 75; (3) The...

  10. 45 CFR 1351.19 - What additional information should an applicant or grantee have about a Runaway and Homeless...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Homeless Youth Program grants. These include: (1) The provisions of 45 CFR part 74 pertaining to the Administration of Grants; (2) The provisions of 45 CFR part 16, Departmental Grants Appeal Process, and the provisions of Informal Grant Appeal Procedures (Indirect Costs) in volume 45 CFR part 75; (3) The...

  11. 45 CFR 1351.19 - What additional information should an applicant or grantee have about a Runaway and Homeless...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Homeless Youth Program grants. These include: (1) The provisions of 45 CFR part 74 pertaining to the Administration of Grants; (2) The provisions of 45 CFR part 16, Departmental Grants Appeal Process, and the provisions of Informal Grant Appeal Procedures (Indirect Costs) in volume 45 CFR part 75; (3) The...

  12. Growth and parameters of microflora in intestinal and faecal samples of piglets due to application of a phytogenic feed additive.

    PubMed

    Muhl, A; Liebert, F

    2007-10-01

    A commercial phytogenic feed additive (PFA), containing the fructopolysaccharide inulin, an essential oil mix (carvacrol, thymol), chestnut meal (tannins) and cellulose powder as carrier substance, was examined for effects on growth and faecal and intestinal microflora of piglets. Two experiments (35 days) were conducted, each with 40 male castrated weaned piglets. In experiment 1, graded levels of the PFA were supplied (A1: control; B1: 0.05% PFA; C1: 0.1% PFA; D1: 0.15% PFA) in diets based on wheat, barley, soybean meal and fish meal with lysine as the limiting amino acid. In experiment 2, a similar diet with 0.1% of the PFA (A2: control; B2: 0.1% PFA; C2: +0.35% lysine; D2: 0.1% PFA + 0.35% lysine) and lysine supplementation was utilized. During experiment 1, no significant effect of the PFA on growth, feed intake and feed conversion rate was observed (p > 0.05). Lysine supplementation in experiment 2 improved growth performance significantly, but no significant effect of the PFA was detected. Microbial counts in faeces (aerobes, Gram negatives, anaerobes and lactobacilli) during the first and fifth week did not indicate any significant PFA effect (p > 0.05). In addition, microflora in intestinal samples was not significantly modified by supplementing the PFA (p > 0.05). Lysine supplementation indicated lysine as limiting amino acid in the basal diet, but did not influence the microbial counts in faeces and small intestine respectively.

  13. High quality Y3Al5O12 doped transparent ceramics for laser applications, role of sintering additives

    NASA Astrophysics Data System (ADS)

    Kaminskii, A. A.; Balashov, V. V.; Cheshev, E. A.; Kopylov, Yu L.; Koromyslov, A. L.; Krokhin, O. N.; Kravchenko, V. B.; Lopukhin, K. V.; Shemet, V. V.; Tupitsyn, I. M.

    2016-08-01

    SiO2, ZrO2, B2O3 and MgO oxides and their combinations were used as sintering aids for preparation of yttrium aluminum garnet (YAG) ceramics doped by Nd2O3, Er2O3, Ho2O3, Tm2O3 and Yb2O3. The influence of these additives on optimal sintering temperature, grain growth, volume of residual pores and optical quality of the ceramics were investigated. The best combination of the sintering additives was found and high quality samples of YAG:Nd (1 at.%) ceramics were obtained. The original method of laser optical quality characterization of ceramics was developed and tested. The main laser parameters of YAG:Nd (1 at.%) ceramics samples are measured and compared with the best well known laser ceramics. The samples of YAG:RE (RE- Er2O3, Ho2O3, Tm2O3 and Yb2O3) ceramics are obtained, and their optical transmittance spectra are measured. Composite structures of YAG:Yb (5 at.%) - YAG were obtained by the simplest method of successive joint compaction of different composition layers.

  14. Optimal Control of Shock Tube Flow via Water Addition with Application to Ignition Overpressure Mitigation in Launch Vehicles

    NASA Astrophysics Data System (ADS)

    Moshman, Nathan

    2009-11-01

    Ignition Overpressure (IOP) in launch vehicles occurs at the start of ignition when a steep rise in pressure propagates outward from the rocket nozzle. It is crucial to minimize the overpressure so as to decrease risk of damage to the rocket body. Currently, CFD studies exist on this situation but there are no optimization studies of the water addition as a means to suppress the IOP. The proposed dissertation will use a numerical method to compute an approximate solution for an optimal control problem constrained by the one-dimensional Euler PDEs of fluid dynamics as well as volume fraction conservation. A model for inter-phase transport of mass momentum and energy and fluid interface quantities will be given. The control will be water addition from external nozzles. The adjoint system of equations will be derived and discretized. Necessary optimal conditions will be derived. An SQP method will solve an optimal situation. Predictions will be validated against shock tube experiments at the NPS rocket lab.

  15. Application of ionic liquid as additive in determination of three β-agonists by capillary electrophoresis with amperometric detection.

    PubMed

    Li, Libo; Du, Hongwei; Yu, Huan; Xu, Lei; You, Tianyan

    2013-01-01

    CE coupled with amperometric detection method was developed using ionic liquid 1-ethyl-3-methylimidazolium tetrafluoroborate (EMImBF(4)) as additive for the simultaneous detection of clenbuterol (CLB), terbutaline (TER), and ractopamine (RAC) in feed. The effects of detection potential, concentration of EMImBF(4), pH, and concentration of the running buffer, separation voltage as well as injection time on the separation and detection of these three β-agonists were investigated in detail. Under the optimum conditions: the detection potential at 1.05 V, 50 mmol/L Tris-HAc at pH 8.0 with 0.6% (v/v) EMImBF(4), electrokinetic injection 6 s at 16 kV and separation voltage at 16 kV, a baseline separation for these three analytes could be achieved within 11 min. Introduction of EMImBF(4) into the running buffer resulted in significant improvement in separation selectivity and enhancement in peak currents for those β-agonists, especially for TER and RAC, which could not be separated in the running buffer without additive. The method exhibited wide linear range with LOD (S/N = 3) of 2, 1, and 2 nmol/L for CLB, TER, and RAC, respectively. The precision was determined in both intraday (n = 5) and interday (n = 3) assays, and the RSDs for both migration time and peak current were less than 6%. The proposed method was also applied to analyze β-agonists in feed sample.

  16. Application of in situ hybridization, cytochemical and immunocytochemical techniques for the investigation of peroxisomes. A review including novel data. Robert Feulgen Prize Lecture 1997.

    PubMed

    Baumgart, E

    1997-09-01

    In situ hybridization, cytochemical and immunocytochemical techniques have contributed significantly to the understanding of the biology of peroxisomes, since they permit in situ demonstration of the sites of synthesis and distribution of peroxisomal proteins without the necessity of homogenization and subcellular fractionation of tissues or cultured cells. This article reviews the results of research on mammalian peroxisomal metabolism, biogenesis and proliferation in which morphological techniques have played a significant role in the elucidation of the biological problem. Some new data on peroxisomal heterogeneity and morphogenesis are included. The morphological methods applied have made it possible to characterize the differences in distribution of mRNAs encoding peroxisomal proteins in different tissues, as well as to monitor the marked heterogeneity in the protein composition and in the activity of specific enzymes in the peroxisomal population of single cells, or in tissues with complex organization (e.g. liver and kidney). In addition, the dynamic alterations and high plasticity of the peroxisomal compartment--partly dependent on contact of the peroxisomes to the microtubular network-are presented.

  17. Application of in situ hybridization, cytochemical and immunocytochemical techniques for the investigation of peroxisomes. A review including novel data. Robert Feulgen Prize Lecture 1997.

    PubMed

    Baumgart, E

    1997-09-01

    In situ hybridization, cytochemical and immunocytochemical techniques have contributed significantly to the understanding of the biology of peroxisomes, since they permit in situ demonstration of the sites of synthesis and distribution of peroxisomal proteins without the necessity of homogenization and subcellular fractionation of tissues or cultured cells. This article reviews the results of research on mammalian peroxisomal metabolism, biogenesis and proliferation in which morphological techniques have played a significant role in the elucidation of the biological problem. Some new data on peroxisomal heterogeneity and morphogenesis are included. The morphological methods applied have made it possible to characterize the differences in distribution of mRNAs encoding peroxisomal proteins in different tissues, as well as to monitor the marked heterogeneity in the protein composition and in the activity of specific enzymes in the peroxisomal population of single cells, or in tissues with complex organization (e.g. liver and kidney). In addition, the dynamic alterations and high plasticity of the peroxisomal compartment--partly dependent on contact of the peroxisomes to the microtubular network-are presented. PMID:9342614

  18. Design and Application of Wuhan Ionospheric Oblique Backscattering Sounding System with the Addition of an Antenna Array (WIOBSS-AA).

    PubMed

    Cui, Xiao; Chen, Gang; Wang, Jin; Song, Huan; Gong, Wanlin

    2016-01-01

    The Wuhan Ionospheric Oblique Backscattering Sounding System with the addition of an antenna array (WIOBSS-AA) is the newest member of the WIOBSS family. It is a multi-channel radio system using phased-array antenna technology. The transmitting part of this radio system applies an array composed of five log-periodic antennas to form five beams that span an area to the northwest of the radar site. The hardware and the antenna array of the first multi-channel ionosonde in the WIOBSS family are introduced in detail in this paper. An ionospheric detection experiment was carried out in Chongyang, Hubei province, China on 16 March 2015 to examine the performance of WIOBSS-AA. The radio system demonstrated its ability to obtain ionospheric electron density information over a wide area. The observations indicate that during the experiment, the monitored large-area ionospheric F2-layer was calm and electron density increased with decreasing latitude. PMID:27314360

  19. Design and Application of Wuhan Ionospheric Oblique Backscattering Sounding System with the Addition of an Antenna Array (WIOBSS-AA)

    PubMed Central

    Cui, Xiao; Chen, Gang; Wang, Jin; Song, Huan; Gong, Wanlin

    2016-01-01

    The Wuhan Ionospheric Oblique Backscattering Sounding System with the addition of an antenna array (WIOBSS-AA) is the newest member of the WIOBSS family. It is a multi-channel radio system using phased-array antenna technology. The transmitting part of this radio system applies an array composed of five log-periodic antennas to form five beams that span an area to the northwest of the radar site. The hardware and the antenna array of the first multi-channel ionosonde in the WIOBSS family are introduced in detail in this paper. An ionospheric detection experiment was carried out in Chongyang, Hubei province, China on 16 March 2015 to examine the performance of WIOBSS-AA. The radio system demonstrated its ability to obtain ionospheric electron density information over a wide area. The observations indicate that during the experiment, the monitored large-area ionospheric F2-layer was calm and electron density increased with decreasing latitude. PMID:27314360

  20. Non-invasive hyperthermia apparatus including coaxial applicator having a non-invasive radiometric receiving antenna incorporated therein and method of use thereof

    DOEpatents

    Ross, M.P.

    1996-08-27

    A coaxial hyperthermia applicator is disclosed for applying non-invasively electromagnetic energy to a body against which it is placed. The coaxial applicator antenna has formed integrally within it a non-invasive radiometric antenna for receiving thermoelectromagnetic emissions. The coaxial-configured applicator produces a bell-shaped radiation pattern symmetric about the axis of symmetry of the coaxial applicator. Integrating the radiometric antenna within the coaxial applicator produces a single device that performs dual functions. The first function is to transmit non-invasively energy for heating a subcutaneous tumor. The second function is to receive non-invasively thermal electromagnetic radiation from the tumor by which temperature is sensed and fed back to control the output of the coaxial applicator. 11 figs.