Science.gov

Sample records for additional computational effort

  1. NASA OSMA NDE Program Additive Manufacturing Foundational Effort

    NASA Technical Reports Server (NTRS)

    Waller, Jess; Walker, James; Burke, Eric; Wells, Douglas; Nichols, Charles

    2016-01-01

    NASA is providing key leadership in an international effort linking NASA and non-NASA resources to speed adoption of additive manufacturing (AM) to meet NASA's mission goals. Participants include industry, NASA's space partners, other government agencies, standards organizations and academia. Nondestructive Evaluation (NDE) is identified as a universal need for all aspects of additive manufacturing.

  2. Calculators and Computers: Graphical Addition.

    ERIC Educational Resources Information Center

    Spero, Samuel W.

    1978-01-01

    A computer program is presented that generates problem sets involving sketching graphs of trigonometric functions using graphical addition. The students use calculators to sketch the graphs and a computer solution is used to check it. (MP)

  3. Summary of NDE of additive manufacturing efforts in NASA

    NASA Astrophysics Data System (ADS)

    Waller, Jess M.; Saulsberry, Regor L.; Parker, Bradford H.; Hodges, Kenneth L.; Burke, Eric R.; Taminger, Karen M.

    2015-03-01

    One of the major obstacles slowing the acceptance of parts made by additive manufacturing (AM) in NASA applications is the lack of a broadly accepted materials and process quality systems; and more specifically, the lack of adequate nondestructive evaluation (NDE) processes integrated into AM. Matching voluntary consensus standards are also needed to control the consistency of input materials, process equipment, process methods, finished part properties, and how those properties are characterized. As for nondestructive characterization, procedures are needed to interrogate features unique to parts made by AM, such as fine-scale porosity, deeply embedded flaws, complex part geometry, and intricate internal features. The NDE methods developed must be tailored to meet materials, design and test requirements encountered throughout the part life cycle, whether during process optimization, real-time process monitoring, finished part qualification and certification (especially of flight hardware), or in situ health monitoring. Restated, individualized process/product-specific NDE methods are needed to satisfy NASA's various quality assurance requirements. To date, only limited data have been acquired by NASA on parts made by AM. This paper summarizes the NASA AM effort, highlights available NDE data, and outlines the approach NASA is taking to apply NDE to its various AM efforts.

  4. Summary of NDE of Additive Manufacturing Efforts in NASA

    NASA Technical Reports Server (NTRS)

    Waller, Jess; Saulsberry, Regor; Parker, Bradford; Hodges, Kenneth; Burke, Eric; Taminger, Karen

    2014-01-01

    (1) General Rationale for Additive Manufacturing (AM): (a) Operate under a 'design-to-constraint' paradigm, make parts too complicated to fabricate otherwise, (b) Reduce weight by 20 percent with monolithic parts, (c) Reduce waste (green manufacturing), (e) Eliminate reliance on Original Equipment Manufacturers for critical spares, and (f) Extend life of in-service parts by innovative repair methods; (2) NASA OSMA NDE of AM State-of-the-Discipline Report; (3) Overview of NASA AM Efforts at Various Centers: (a) Analytical Tools, (b) Ground-Based Fabrication (c) Space-Based Fabrication; and (d) Center Activity Summaries; (4) Overview of NASA NDE data to date on AM parts; and (5) Gap Analysis/Recommendations for NDE of AM.

  5. 42 CFR 441.182 - Maintenance of effort: Computation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Maintenance of effort: Computation. 441.182 Section 441.182 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... § 441.182 Maintenance of effort: Computation. (a) For expenditures for inpatient psychiatric...

  6. 42 CFR 441.182 - Maintenance of effort: Computation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SERVICES Inpatient Psychiatric Services for Individuals Under Age 21 in Psychiatric Facilities or Programs § 441.182 Maintenance of effort: Computation. (a) For expenditures for inpatient psychiatric services... total State Medicaid expenditures in the current quarter for inpatient psychiatric services...

  7. 42 CFR 441.182 - Maintenance of effort: Computation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... SERVICES Inpatient Psychiatric Services for Individuals Under Age 21 in Psychiatric Facilities or Programs § 441.182 Maintenance of effort: Computation. (a) For expenditures for inpatient psychiatric services... total State Medicaid expenditures in the current quarter for inpatient psychiatric services...

  8. 42 CFR 441.182 - Maintenance of effort: Computation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... SERVICES Inpatient Psychiatric Services for Individuals Under Age 21 in Psychiatric Facilities or Programs § 441.182 Maintenance of effort: Computation. (a) For expenditures for inpatient psychiatric services... total State Medicaid expenditures in the current quarter for inpatient psychiatric services...

  9. 42 CFR 441.182 - Maintenance of effort: Computation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... SERVICES Inpatient Psychiatric Services for Individuals Under Age 21 in Psychiatric Facilities or Programs § 441.182 Maintenance of effort: Computation. (a) For expenditures for inpatient psychiatric services... total State Medicaid expenditures in the current quarter for inpatient psychiatric services...

  10. Combining Computational and Social Effort for Collaborative Problem Solving.

    PubMed

    Wagy, Mark D; Bongard, Josh C

    2015-01-01

    Rather than replacing human labor, there is growing evidence that networked computers create opportunities for collaborations of people and algorithms to solve problems beyond either of them. In this study, we demonstrate the conditions under which such synergy can arise. We show that, for a design task, three elements are sufficient: humans apply intuitions to the problem, algorithms automatically determine and report back on the quality of designs, and humans observe and innovate on others' designs to focus creative and computational effort on good designs. This study suggests how such collaborations should be composed for other domains, as well as how social and computational dynamics mutually influence one another during collaborative problem solving.

  11. New Mexico district work-effort analysis computer program

    USGS Publications Warehouse

    Hiss, W.L.; Trantolo, A.P.; Sparks, J.L.

    1972-01-01

    The computer program (CAN 2) described in this report is one of several related programs used in the New Mexico District cost-analysis system. The work-effort information used in these programs is accumulated and entered to the nearest hour on forms completed by each employee. Tabulating cards are punched directly from these forms after visual examinations for errors are made. Reports containing detailed work-effort data itemized by employee within each project and account and by account and project for each employee are prepared for both current-month and year-to-date periods by the CAN 2 computer program. An option allowing preparation of reports for a specified 3-month period is provided. The total number of hours worked on each account and project and a grand total of hours worked in the New Mexico District is computed and presented in a summary report for each period. Work effort not chargeable directly to individual projects or accounts is considered as overhead and can be apportioned to the individual accounts and projects on the basis of the ratio of the total hours of work effort for the individual accounts or projects to the total New Mexico District work effort at the option of the user. The hours of work performed by a particular section, such as General Investigations or Surface Water, are prorated and charged to the projects or accounts within the particular section. A number of surveillance or buffer accounts are employed to account for the hours worked on special events or on those parts of large projects or accounts that require a more detailed analysis. Any part of the New Mexico District operation can be separated and analyzed in detail by establishing an appropriate buffer account. With the exception of statements associated with word size, the computer program is written in FORTRAN IV in a relatively low and standard language level to facilitate its use on different digital computers. The program has been run only on a Control Data Corporation

  12. Combining Computational and Social Effort for Collaborative Problem Solving

    PubMed Central

    Wagy, Mark D.; Bongard, Josh C.

    2015-01-01

    Rather than replacing human labor, there is growing evidence that networked computers create opportunities for collaborations of people and algorithms to solve problems beyond either of them. In this study, we demonstrate the conditions under which such synergy can arise. We show that, for a design task, three elements are sufficient: humans apply intuitions to the problem, algorithms automatically determine and report back on the quality of designs, and humans observe and innovate on others’ designs to focus creative and computational effort on good designs. This study suggests how such collaborations should be composed for other domains, as well as how social and computational dynamics mutually influence one another during collaborative problem solving. PMID:26544199

  13. The Computer Fraud and Abuse Act of 1986 and the Computer Security Act of 1987: Impact on incident response efforts

    SciTech Connect

    Schultz, E.E.

    1991-10-11

    The purpose of this paper is to evaluate two Federal statutes, the Computer Fraud and Abuse Act of 1986 and the Computer Security Act of 1987, from the perspective of computer security incident response efforts. First, the major relevant provisions of each statute are presented. Next, revisions to each statute are proposed, and additional areas needing to be addressed in future legislation are presented. The major conclusion is that these statutes represent a start in the legislative process to deter and prevent computer offenses such as unauthorized access to systems. However, many revisions and additions are needed before such legislation will significantly impact incident response efforts. In addition, legislation alone cannot bring about the degree of change necessary to address the range of computer security threats that presently exist.

  14. Computer Maintenance Operations Center (CMOC), additional computer support equipment ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Computer Maintenance Operations Center (CMOC), additional computer support equipment - Beale Air Force Base, Perimeter Acquisition Vehicle Entry Phased-Array Warning System, Techinical Equipment Building, End of Spencer Paul Road, north of Warren Shingle Road (14th Street), Marysville, Yuba County, CA

  15. Defense Additive Manufacturing: DOD Needs to Systematically Track Department-wide 3D Printing Efforts

    DTIC Science & Technology

    2015-10-01

    Clip Additively Manufactured • The Navy installed a 3D printer aboard the USS Essex to demonstrate the ability to additively develop and produce...desired result and vision to have the capability on the fleet. These officials stated that the Navy plans to install 3D printers on two additional...DEFENSE ADDITIVE MANUFACTURING DOD Needs to Systematically Track Department-wide 3D Printing Efforts Report to

  16. Using individual interest and conscientiousness to predict academic effort: Additive, synergistic, or compensatory effects?

    PubMed

    Trautwein, Ulrich; Lüdtke, Oliver; Nagy, Nicole; Lenski, Anna; Niggli, Alois; Schnyder, Inge

    2015-07-01

    Although both conscientiousness and domain-specific interest are believed to be major determinants of academic effort, they have rarely been brought together in empirical studies. In the present research, it was hypothesized that both interest and conscientiousness uniquely predict academic effort and statistically interact with each other to predict academic effort. In 4 studies with 2,557, 415, 1,025, and 1,531 students, respectively, conscientiousness and interest meaningfully and uniquely predicted academic effort. In addition, conscientiousness interacted with interest in a compensatory pattern, indicating that conscientiousness is especially important when a student finds a school subject uninteresting and that domain-specific interest plays a particularly important role for students low in conscientiousness.

  17. Computational Process Modeling for Additive Manufacturing

    NASA Technical Reports Server (NTRS)

    Bagg, Stacey; Zhang, Wei

    2014-01-01

    Computational Process and Material Modeling of Powder Bed additive manufacturing of IN 718. Optimize material build parameters with reduced time and cost through modeling. Increase understanding of build properties. Increase reliability of builds. Decrease time to adoption of process for critical hardware. Potential to decrease post-build heat treatments. Conduct single-track and coupon builds at various build parameters. Record build parameter information and QM Meltpool data. Refine Applied Optimization powder bed AM process model using data. Report thermal modeling results. Conduct metallography of build samples. Calibrate STK models using metallography findings. Run STK models using AO thermal profiles and report STK modeling results. Validate modeling with additional build. Photodiode Intensity measurements highly linear with power input. Melt Pool Intensity highly correlated to Melt Pool Size. Melt Pool size and intensity increase with power. Applied Optimization will use data to develop powder bed additive manufacturing process model.

  18. Instructional Computing for the Health Sciences: A Cooperative Effort

    PubMed Central

    Ellis, Lynda B.M.; Hannigan, Gale G.

    1984-01-01

    For more than a decade, the University of Minnesota has provided support for instructional computing in the health sciences. Successful management of this learning resource depends on continuing cooperation of and coordination by several academic and administrative units. We describe the past and present status of this growing resource, as well as planning for future development.

  19. Developing a framework for assessing muscle effort and postures during computer work in the field: the effect of computer activities on neck/shoulder muscle effort and postures.

    PubMed

    Bruno Garza, J L; Eijckelhof, B H W; Johnson, P W; Raina, S M; Rynell, P; Huysmans, M A; van Dieën, J H; van der Beek, A J; Blatter, B M; Dennerlein, J T

    2012-01-01

    The present study, a part of the PROOF (PRedicting Occupational biomechanics in OFfice workers) study, aimed to determine whether trapezius muscle effort was different across computer activities in a field study of computer workers, and also investigated whether head and shoulder postures were different across computer activities. One hundred twenty participants were measured continuously for two hours each while performing their own computer work. Keyboard activities were associated with the highest intensity of left and right trapezius muscle efforts, and mouse activities were associated with the smallest variability in left and right trapezius muscle efforts. Corresponding trends in head and shoulder postures included that the greatest head flexion and left and right shoulder internal rotation was observed during keyboard activities, and that the smallest variability in head flexion, head lateral tilt, and right shoulder internal rotation was observed during mouse activities. Identifying which muscle efforts and postures are different across computer activities is the first essential step for developing prediction rules for muscle efforts and postures, which can be used to link muscle efforts and postures to musculoskeletal symptoms in epidemiological studies.

  20. Computational Process Modeling for Additive Manufacturing (OSU)

    NASA Technical Reports Server (NTRS)

    Bagg, Stacey; Zhang, Wei

    2015-01-01

    Powder-Bed Additive Manufacturing (AM) through Direct Metal Laser Sintering (DMLS) or Selective Laser Melting (SLM) is being used by NASA and the Aerospace industry to "print" parts that traditionally are very complex, high cost, or long schedule lead items. The process spreads a thin layer of metal powder over a build platform, then melts the powder in a series of welds in a desired shape. The next layer of powder is applied, and the process is repeated until layer-by-layer, a very complex part can be built. This reduces cost and schedule by eliminating very complex tooling and processes traditionally used in aerospace component manufacturing. To use the process to print end-use items, NASA seeks to understand SLM material well enough to develop a method of qualifying parts for space flight operation. Traditionally, a new material process takes many years and high investment to generate statistical databases and experiential knowledge, but computational modeling can truncate the schedule and cost -many experiments can be run quickly in a model, which would take years and a high material cost to run empirically. This project seeks to optimize material build parameters with reduced time and cost through modeling.

  1. Computed tomography characterisation of additive manufacturing materials.

    PubMed

    Bibb, Richard; Thompson, Darren; Winder, John

    2011-06-01

    Additive manufacturing, covering processes frequently referred to as rapid prototyping and rapid manufacturing, provides new opportunities in the manufacture of highly complex and custom-fitting medical devices and products. Whilst many medical applications of AM have been explored and physical properties of the resulting parts have been studied, the characterisation of AM materials in computed tomography has not been explored. The aim of this study was to determine the CT number of commonly used AM materials. There are many potential applications of the information resulting from this study in the design and manufacture of wearable medical devices, implants, prostheses and medical imaging test phantoms. A selection of 19 AM material samples were CT scanned and the resultant images analysed to ascertain the materials' CT number and appearance in the images. It was found that some AM materials have CT numbers very similar to human tissues, FDM, SLA and SLS produce samples that appear uniform on CT images and that 3D printed materials show a variation in internal structure.

  2. Computational Efforts in Support of Advanced Coal Research

    SciTech Connect

    Suljo Linic

    2006-08-17

    The focus in this project was to employ first principles computational methods to study the underlying molecular elementary processes that govern hydrogen diffusion through Pd membranes as well as the elementary processes that govern the CO- and S-poisoning of these membranes. Our computational methodology integrated a multiscale hierarchical modeling approach, wherein a molecular understanding of the interactions between various species is gained from ab-initio quantum chemical Density Functional Theory (DFT) calculations, while a mesoscopic statistical mechanical model like Kinetic Monte Carlo is employed to predict the key macroscopic membrane properties such as permeability. The key developments are: (1) We have coupled systematically the ab initio calculations with Kinetic Monte Carlo (KMC) simulations to model hydrogen diffusion through the Pd based-membranes. The predicted tracer diffusivity of hydrogen atoms through the bulk of Pd lattice from KMC simulations are in excellent agreement with experiments. (2) The KMC simulations of dissociative adsorption of H{sub 2} over Pd(111) surface indicates that for thin membranes (less than 10{micro} thick), the diffusion of hydrogen from surface to the first subsurface layer is rate limiting. (3) Sulfur poisons the Pd surface by altering the electronic structure of the Pd atoms in the vicinity of the S atom. The KMC simulations indicate that increasing sulfur coverage drastically reduces the hydrogen coverage on the Pd surface and hence the driving force for diffusion through the membrane.

  3. Computational and Experimental Efforts in Gravity Probe B Microthruster Analysis

    NASA Technical Reports Server (NTRS)

    Droege, Alan; Smith, Andrew; Carter, James

    1996-01-01

    Gravity Probe B, an experiment to test the theory of relativity, will be launched near the turn of the millennium. Due to the precise pointing requirements need to successfully carry out this experiment, the satellite will use sixteen proportionally controlled microthrusters as a main component of the attitude control system. These microthrusters use the helium boil-off from the on-board dewar as propellant. Marshall Space Flight Center, verified the design of the thruster flow path by both computational and experimental methods. The flow performance of the thruster has been adequately characterized. Graphs show specific impulse, thrust coefficient, discharge coefficient, and mass flow rate trends. Value was added to the program through gained confidence in the design of the thruster and through valuation of some design trade-offs.

  4. Structured additive distributional regression for analysing landings per unit effort in fisheries research.

    PubMed

    Mamouridis, Valeria; Klein, Nadja; Kneib, Thomas; Cadarso Suarez, Carmen; Maynou, Francesc

    2017-01-01

    We analysed the landings per unit effort (LPUE) from the Barcelona trawl fleet targeting the red shrimp (Aristeus antennatus) using novel Bayesian structured additive distributional regression to gain a better understanding of the dynamics and determinants of variation in LPUE. The data set, covering a time span of 17 years, includes fleet-dependent variables (e.g. the number of trips performed by vessels), temporal variables (inter- and intra-annual variability) and environmental variables (the North Atlantic Oscillation index). Based on structured additive distributional regression, we evaluate (i) the gain in replacing purely linear predictors by additive predictors including nonlinear effects of continuous covariates, (ii) the inclusion of vessel-specific effects based on either fixed or random effects, (iii) different types of distributions for the response, and (iv) the potential gain in not only modelling the location but also the scale/shape parameter of these distributions. Our findings support that flexible model variants are indeed able to improve the fit considerably and that additional insights can be gained. Tools to select within several model specifications and assumptions are discussed in detail as well.

  5. DOD Financial Management: Additional Efforts Needed to Improve Audit Readiness of Navy Military Pay and Other Related Activities

    DTIC Science & Technology

    2015-09-01

    DOD FINANCIAL MANAGEMENT Additional Efforts Needed to Improve Audit Readiness of Navy Military Pay and Other Related...REPORT TYPE 3. DATES COVERED 00-00-2015 to 00-00-2015 4. TITLE AND SUBTITLE DOD Financial Management: Additional Efforts Needed to Improve Audit ...Additional Efforts Needed to Improve Audit Readiness of Navy Military Pay and Other Related Activities Why GAO Did This Study DOD continues to work

  6. Department of Energy Efforts to Promote Universal Adherence to the IAEA Additional Protocol

    SciTech Connect

    Killinger, Mark H.; Hansen, Linda H.; Kovacic, Don N.; VanSickle, Matthew; Apt, Kenneth E.

    2009-10-06

    Entry-into-force of the U.S. Additional Protocol (AP) in January 2009 continues to demonstrate the ongoing commitment by the United States to promote universal adherence to the AP. The AP is a critical tool for improving the International Atomic Energy Agency’s (IAEA) capabilities to detect undeclared activities that indicate a clandestine nuclear weapons program. This is because States Parties are required to provide information about, and access to, nuclear fuel cycle activities beyond their traditional safeguards reporting requirements. As part of the U.S. AP Implementation Act and Senate Resolution of Ratification, the Administration is required to report annually to Congress on measures taken to achieve the adoption of the AP in non-nuclear weapon states, as well as assistance to the IAEA to promote the effective implementation of APs in those states. A key U.S. effort in this area is being managed by the International Nuclear Safeguards and Engagement Program (INSEP) of the U.S. Department of Energy (DOE). Through new and existing bilateral cooperation agreements, INSEP has initiated technical assistance projects for AP implementation with selected non-weapon states. States with which INSEP is currently cooperating include Vietnam and Thailand, with Indonesia, Algeria, Morocco, and other countries as possible future collaborators in the area of AP implementation. The INSEP collaborative model begins with a joint assessment with our partners to identify specific needs they may have regarding entering the AP into force and any impediments to successful implementation. An action plan is then developed detailing and prioritizing the necessary joint activities. Such assistance may include: advice on developing legal frameworks and regulatory documents; workshops to promote understanding of AP requirements; training to determine possible declarable activities; assistance in developing a system to collect and submit declarations; performing industry outreach to

  7. Effort cost computation in schizophrenia: a commentary on the recent literature.

    PubMed

    Gold, James M; Waltz, James A; Frank, Michael J

    2015-12-01

    The cognitive and affective factors implicated in the motivational impairments seen in many people with schizophrenia remain poorly understood. Many research groups have done studies in the past 2 years examining the role of effort-cost computations driven by the hypothesis that overestimation of the cost of effort involved in volitional behavior might underlie the reduction in goal-directed behavior seen in some people with schizophrenia. The goal of this review is to assess the available evidence and the interpretative ambiguities that remain to be addressed by further studies. There is a clear preponderance of evidence suggesting that people with schizophrenia demonstrate altered effort allocation by failing to make high-effort response choices to maximize reward. The evidence relating altered effort allocation to the severity of negative symptoms is mixed. It remains for future work to determine the precise mechanisms implicated in altered effort allocation with two prominent possibilities: that patients 1) overestimate the cost of effort or 2) underestimate the value of potential awards. Other mechanisms that need to be investigated include the potential contributions of other impairments associated with the illness that increase the cost of effort. Furthermore, it is possible that accurate value representations fail to invigorate behavior. Although questions remain, evidence available to date suggests that the study of cost/benefit decision making may shed new light on the motivational impairments seen in many people with schizophrenia.

  8. Additional support for the TDK/MABL computer program

    NASA Technical Reports Server (NTRS)

    Nickerson, G. R.; Dunn, Stuart S.

    1993-01-01

    An advanced version of the Two-Dimensional Kinetics (TDK) computer program was developed under contract and released to the propulsion community in early 1989. Exposure of the code to this community indicated a need for improvements in certain areas. In particular, the TDK code needed to be adapted to the special requirements imposed by the Space Transportation Main Engine (STME) development program. This engine utilizes injection of the gas generator exhaust into the primary nozzle by means of a set of slots. The subsequent mixing of this secondary stream with the primary stream with finite rate chemical reaction can have a major impact on the engine performance and the thermal protection of the nozzle wall. In attempting to calculate this reacting boundary layer problem, the Mass Addition Boundary Layer (MABL) module of TDK was found to be deficient in several respects. For example, when finite rate chemistry was used to determine gas properties, (MABL-K option) the program run times became excessive because extremely small step sizes were required to maintain numerical stability. A robust solution algorithm was required so that the MABL-K option could be viable as a rocket propulsion industry design tool. Solving this problem was a primary goal of the phase 1 work effort.

  9. Motivational Beliefs, Student Effort, and Feedback Behaviour in Computer-Based Formative Assessment

    ERIC Educational Resources Information Center

    Timmers, Caroline F.; Braber-van den Broek, Jannie; van den Berg, Stephanie M.

    2013-01-01

    Feedback can only be effective when students seek feedback and process it. This study examines the relations between students' motivational beliefs, effort invested in a computer-based formative assessment, and feedback behaviour. Feedback behaviour is represented by whether a student seeks feedback and the time a student spends studying the…

  10. DARPA-funded efforts in the development of novel brain-computer interface technologies.

    PubMed

    Miranda, Robbin A; Casebeer, William D; Hein, Amy M; Judy, Jack W; Krotkov, Eric P; Laabs, Tracy L; Manzo, Justin E; Pankratz, Kent G; Pratt, Gill A; Sanchez, Justin C; Weber, Douglas J; Wheeler, Tracey L; Ling, Geoffrey S F

    2015-04-15

    The Defense Advanced Research Projects Agency (DARPA) has funded innovative scientific research and technology developments in the field of brain-computer interfaces (BCI) since the 1970s. This review highlights some of DARPA's major advances in the field of BCI, particularly those made in recent years. Two broad categories of DARPA programs are presented with respect to the ultimate goals of supporting the nation's warfighters: (1) BCI efforts aimed at restoring neural and/or behavioral function, and (2) BCI efforts aimed at improving human training and performance. The programs discussed are synergistic and complementary to one another, and, moreover, promote interdisciplinary collaborations among researchers, engineers, and clinicians. Finally, this review includes a summary of some of the remaining challenges for the field of BCI, as well as the goals of new DARPA efforts in this domain.

  11. DOE's Effort to Reduce Truck Aerodynamic Drag-Joint Experiments and Computations Lead to Smart Design

    SciTech Connect

    McCallen, R; Salari, K; Ortega, J; DeChant, L; Hassan, B; Roy, C; Pointer, W; Browand, F; Hammache, M; Hsu, T; Leonard, A; Rubel, M; Chatalain, P; Englar, R; Ross, J; Satran, D; Heineck, J; Walker, S; Yaste, D; Storms, B

    2004-06-17

    At 70 miles per hour, overcoming aerodynamic drag represents about 65% of the total energy expenditure for a typical heavy truck vehicle. The goal of this US Department of Energy supported consortium is to establish a clear understanding of the drag producing flow phenomena. This is being accomplished through joint experiments and computations, leading to the 'smart' design of drag reducing devices. This paper will describe our objective and approach, provide an overview of our efforts and accomplishments, and discuss our future direction.

  12. DOE's effort to reduce truck aerodynamic drag : joint experiments and computations lead to smart design.

    SciTech Connect

    Yaste, David M; Salari, Kambiz; Hammache, Mustapha; Browand, Fred; Pointer, W. David; Ortega, Jason M.; McCallen, Rose; Walker, Stephen M; Heineck, James T; Hassan, Basil; Roy, Christopher John; Storms, B.; Satran, D.; Ross, James; Englar, Robert; Chatalain, Philippe; Rubel, Mike; Leonard, Anthony; Hsu, Tsu-Ya; DeChant, Lawrence Justin.

    2004-06-01

    At 70 miles per hour, overcoming aerodynamic drag represents about 65% of the total energy expenditure for a typical heavy truck vehicle. The goal of this US Department of Energy supported consortium is to establish a clear understanding of the drag producing flow phenomena. This is being accomplished through joint experiments and computations, leading to the smart design of drag reducing devices. This paper will describe our objective and approach, provide an overview of our efforts and accomplishments, and discuss our future direction.

  13. Collaborative Efforts for Representing Nursing Concepts in Computer-based Systems

    PubMed Central

    Coenen, Amy; Marin, Heimar F.; Park, Hyeoun-Ae; Bakken, Suzanne

    2001-01-01

    Current nursing terminology efforts have converged toward meeting the demand for a reference terminology for nursing concepts by building on the foundation of existing interface and administrative terminologies and by collaborating with terminology efforts across the spectrum of health care. In this article, the authors illustrate how collaboration is promoting convergence toward a reference terminology for nursing by briefly summarizing a wide range of exemplary activities. These include: 1) the International Classification of Nursing Practice (ICNP) activities of the International Council of Nurses (ICN), 2) work in Brazil and Korea that has contributed to, and been stimulated by, ICNP developments, 3) efforts in the United States to improve understanding of the different types of terminologies needed in nursing and to promote harmonization and linking among them, and 4) current nursing participation in major multi-disciplinary standards initiatives. Although early nursing terminology work occurred primarily in isolation and resulted in some duplicative efforts, the activities summarized in this article demonstrate a tremendous level of collaboration and convergence not only in the discipline of nursing but in multi-disciplinary standards initiatives. These efforts are an important prerequisite for ensuring that nursing concepts are represented in computer-based systems in a manner that facilitates multi-purpose use at local, national, regional, and international levels. PMID:11320065

  14. Human Capital: Additional Actions Needed to Enhance DOD’s Efforts to Address Mental Health Care Stigma

    DTIC Science & Technology

    2016-04-01

    stress disorder or traumatic brain injury. Additionally, the Defense Suicide Prevention Office reports through the Executive Director of the Office of...Efforts to Address Mental Health Care Stigma Why GAO Did This Study A 2010 DOD task force on suicide prevention concluded that stigma—the negative...Representatives A 2010 Department of Defense (DOD) Task Force on the Prevention of Suicide by Members of the Armed Forces concluded that

  15. Unmanned Aircraft Systems: Additional Actions Needed to Improve Management and Integration of DOD Efforts to Support Warfighter Needs

    DTIC Science & Technology

    2008-11-01

    Services, House of Representatives UNMANNED AIRCRAFT SYSTEMS Additional Actions Needed to Improve Management and Integration of DOD Efforts to...Armed Services, House of Representatives The Department of Defense’s (DOD) use of unmanned aircraft systems (UAS) continues to increase. In 2000...unmanned aircraft systems This is a work of the U.S. government and is not subject to copyright protection in the United States. It may be reproduced

  16. Computed Tomography Inspection and Analysis for Additive Manufacturing Components

    NASA Technical Reports Server (NTRS)

    Beshears, Ronald D.

    2016-01-01

    Computed tomography (CT) inspection was performed on test articles additively manufactured from metallic materials. Metallic AM and machined wrought alloy test articles with programmed flaws were inspected using a 2MeV linear accelerator based CT system. Performance of CT inspection on identically configured wrought and AM components and programmed flaws was assessed using standard image analysis techniques to determine the impact of additive manufacturing on inspectability of objects with complex geometries.

  17. 34 CFR 461.45 - How does the Secretary compute maintenance of effort in the event of a waiver?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false How does the Secretary compute maintenance of effort in the event of a waiver? 461.45 Section 461.45 Education Regulations of the Offices of the Department of... Secretary compute maintenance of effort in the event of a waiver? If a State has been granted a waiver...

  18. 34 CFR 403.185 - How does the Secretary compute maintenance of effort in the event of a waiver?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false How does the Secretary compute maintenance of effort in the event of a waiver? 403.185 Section 403.185 Education Regulations of the Offices of the Department....185 How does the Secretary compute maintenance of effort in the event of a waiver? If a State has...

  19. Lawrence Livermore National Laboratories Perspective on Code Development and High Performance Computing Resources in Support of the National HED/ICF Effort

    SciTech Connect

    Clouse, C. J.; Edwards, M. J.; McCoy, M. G.; Marinak, M. M.; Verdon, C. P.

    2015-07-07

    Through its Advanced Scientific Computing (ASC) and Inertial Confinement Fusion (ICF) code development efforts, Lawrence Livermore National Laboratory (LLNL) provides a world leading numerical simulation capability for the National HED/ICF program in support of the Stockpile Stewardship Program (SSP). In addition the ASC effort provides high performance computing platform capabilities upon which these codes are run. LLNL remains committed to, and will work with, the national HED/ICF program community to help insure numerical simulation needs are met and to make those capabilities available, consistent with programmatic priorities and available resources.

  20. Understanding climate-induced migration through computational modeling: A critical overview with guidance for future efforts

    DOE PAGES

    Till, Charlotte; Haverkamp, Jamie; White, Devin; ...

    2016-11-22

    Climate change has the potential to displace large populations in many parts of the developed and developing world. Understanding why, how, and when environmental migrants decide to move is critical to successful strategic planning within organizations tasked with helping the affected groups, and mitigating their systemic impacts. One way to support planning is through the employment of computational modeling techniques. Models can provide a window into possible futures, allowing planners and decision makers to test different scenarios in order to understand what might happen. While modeling is a powerful tool, it presents both opportunities and challenges. This paper builds amore » foundation for the broader community of model consumers and developers by: providing an overview of pertinent climate-induced migration research, describing some different types of models and how to select the most relevant one(s), highlighting three perspectives on obtaining data to use in said model(s), and the consequences associated with each. It concludes with two case studies based on recent research that illustrate what can happen when ambitious modeling efforts are undertaken without sufficient planning, oversight, and interdisciplinary collaboration. Lastly, we hope that the broader community can learn from our experiences and apply this knowledge to their own modeling research efforts.« less

  1. Understanding climate-induced migration through computational modeling: A critical overview with guidance for future efforts

    SciTech Connect

    Till, Charlotte; Haverkamp, Jamie; White, Devin; Bhaduri, Budhendra

    2016-11-22

    Climate change has the potential to displace large populations in many parts of the developed and developing world. Understanding why, how, and when environmental migrants decide to move is critical to successful strategic planning within organizations tasked with helping the affected groups, and mitigating their systemic impacts. One way to support planning is through the employment of computational modeling techniques. Models can provide a window into possible futures, allowing planners and decision makers to test different scenarios in order to understand what might happen. While modeling is a powerful tool, it presents both opportunities and challenges. This paper builds a foundation for the broader community of model consumers and developers by: providing an overview of pertinent climate-induced migration research, describing some different types of models and how to select the most relevant one(s), highlighting three perspectives on obtaining data to use in said model(s), and the consequences associated with each. It concludes with two case studies based on recent research that illustrate what can happen when ambitious modeling efforts are undertaken without sufficient planning, oversight, and interdisciplinary collaboration. Lastly, we hope that the broader community can learn from our experiences and apply this knowledge to their own modeling research efforts.

  2. U.S. EPA computational toxicology programs: Central role of chemical-annotation efforts and molecular databases

    EPA Science Inventory

    EPA’s National Center for Computational Toxicology is engaged in high-profile research efforts to improve the ability to more efficiently and effectively prioritize and screen thousands of environmental chemicals for potential toxicity. A central component of these efforts invol...

  3. Technology and Sexuality--What's the Connection? Addressing Youth Sexualities in Efforts to Increase Girls' Participation in Computing

    ERIC Educational Resources Information Center

    Ashcraft, Catherine

    2015-01-01

    To date, girls and women are significantly underrepresented in computer science and technology. Concerns about this underrepresentation have sparked a wealth of educational efforts to promote girls' participation in computing, but these programs have demonstrated limited impact on reversing current trends. This paper argues that this is, in part,…

  4. X-ray computed tomography for additive manufacturing: a review

    NASA Astrophysics Data System (ADS)

    Thompson, A.; Maskery, I.; Leach, R. K.

    2016-07-01

    In this review, the use of x-ray computed tomography (XCT) is examined, identifying the requirement for volumetric dimensional measurements in industrial verification of additively manufactured (AM) parts. The XCT technology and AM processes are summarised, and their historical use is documented. The use of XCT and AM as tools for medical reverse engineering is discussed, and the transition of XCT from a tool used solely for imaging to a vital metrological instrument is documented. The current states of the combined technologies are then examined in detail, separated into porosity measurements and general dimensional measurements. In the conclusions of this review, the limitation of resolution on improvement of porosity measurements and the lack of research regarding the measurement of surface texture are identified as the primary barriers to ongoing adoption of XCT in AM. The limitations of both AM and XCT regarding slow speeds and high costs, when compared to other manufacturing and measurement techniques, are also noted as general barriers to continued adoption of XCT and AM.

  5. Finding a balance between accuracy and computational effort for modeling biomineralization

    NASA Astrophysics Data System (ADS)

    Hommel, Johannes; Ebigbo, Anozie; Gerlach, Robin; Cunningham, Alfred B.; Helmig, Rainer; Class, Holger

    2016-04-01

    One of the key issues of underground gas storage is the long-term security of the storage site. Amongst the different storage mechanisms, cap-rock integrity is crucial for preventing leakage of the stored gas due to buoyancy into shallower aquifers or, ultimately, the atmosphere. This leakage would reduce the efficiency of underground gas storage and pose a threat to the environment. Ureolysis-driven, microbially induced calcite precipitation (MICP) is one of the technologies in the focus of current research aiming at mitigation of potential leakage by sealing high-permeability zones in cap rocks. Previously, a numerical model, capable of simulating two-phase multi-component reactive transport, including the most important processes necessary to describe MICP, was developed and validated against experiments in Ebigbo et al. [2012]. The microbial ureolysis kinetics implemented in the model was improved based on new experimental findings and the model was recalibrated using improved experimental data in Hommel et al. [2015]. This increased the ability of the model to predict laboratory experiments while simplifying some of the reaction rates. However, the complexity of the model is still high which leads to high computation times even for relatively small domains. The high computation time prohibits the use of the model for the design of field-scale applications of MICP. Various approaches to reduce the computational time are possible, e.g. using optimized numerical schemes or simplified engineering models. Optimized numerical schemes have the advantage of conserving the detailed equations, as they save computation time by an improved solution strategy. Simplified models are more an engineering approach, since they neglect processes of minor impact and focus on the processes which have the most influence on the model results. This allows also for investigating the influence of a certain process on the overall MICP, which increases the insights into the interactions

  6. Child Effortful Control, Teacher-Student Relationships, and Achievement in Academically At-Risk Children: Additive and Interactive Effects

    ERIC Educational Resources Information Center

    Liew, Jeffrey; Chen, Qi; Hughes, Jan N.

    2010-01-01

    The joint contributions of child effortful control (using inhibitory control and task accuracy as behavioral indices) and positive teacher-student relationships at first grade on reading and mathematics achievement at second grade were examined in 761 children who were predominantly from low-income and ethnic minority backgrounds and assessed to…

  7. Twenty Years of Girls into Computing Days: Has It Been Worth the Effort?

    ERIC Educational Resources Information Center

    Craig, Annemieke; Lang, Catherine; Fisher, Julie

    2008-01-01

    The first documented day-long program to encourage girls to consider computing as a career was held in 1987 in the U.K. Over the last 20 years these one-day events, labeled "Girls into Computing" days, have been conducted by academics and professionals to foster female-student interest in information technology (IT) degrees and careers.…

  8. Child Effortful Control, Teacher-student Relationships, and Achievement in Academically At-risk Children: Additive and Interactive Effects.

    PubMed

    Liew, Jeffrey; Chen, Qi; Hughes, Jan N

    2010-01-01

    The joint contributions of child effortful control (using inhibitory control and task accuracy as behavioral indices) and positive teacher-student relationships at first grade on reading and mathematics achievement at second grade were examined in 761 children who were predominantly from low-income and ethnic minority backgrounds and assessed to be academically at-risk at entry to first grade. Analyses accounted for clustering effects, covariates, baselines of effortful control measures, and prior levels of achievement. Even with such conservative statistical controls, interactive effects were found for task accuracy and positive teacher-student relationships on future achievement. Results suggest that task accuracy served as a protective factor so that children with high task accuracy performed well academically despite not having positive teacher-student relationships. Further, positive teacher-student relationships served as a compensatory factor so that children with low task accuracy performed just as well as those with high task accuracy if they were paired with a positive and supportive teacher. Importantly, results indicate that the influence of positive teacher-student relationships on future achievement was most pronounced for students with low effortful control on tasks that require fine motor skills, accuracy, and attention-related skills. Study results have implications for narrowing achievement disparities for academically at-risk children.

  9. Child Effortful Control, Teacher-student Relationships, and Achievement in Academically At-risk Children: Additive and Interactive Effects

    PubMed Central

    Liew, Jeffrey; Chen, Qi; Hughes, Jan N.

    2009-01-01

    The joint contributions of child effortful control (using inhibitory control and task accuracy as behavioral indices) and positive teacher-student relationships at first grade on reading and mathematics achievement at second grade were examined in 761 children who were predominantly from low-income and ethnic minority backgrounds and assessed to be academically at-risk at entry to first grade. Analyses accounted for clustering effects, covariates, baselines of effortful control measures, and prior levels of achievement. Even with such conservative statistical controls, interactive effects were found for task accuracy and positive teacher-student relationships on future achievement. Results suggest that task accuracy served as a protective factor so that children with high task accuracy performed well academically despite not having positive teacher-student relationships. Further, positive teacher-student relationships served as a compensatory factor so that children with low task accuracy performed just as well as those with high task accuracy if they were paired with a positive and supportive teacher. Importantly, results indicate that the influence of positive teacher-student relationships on future achievement was most pronounced for students with low effortful control on tasks that require fine motor skills, accuracy, and attention-related skills. Study results have implications for narrowing achievement disparities for academically at-risk children. PMID:20161421

  10. Additional extensions to the NASCAP computer code, volume 3

    NASA Technical Reports Server (NTRS)

    Mandell, M. J.; Cooke, D. L.

    1981-01-01

    The ION computer code is designed to calculate charge exchange ion densities, electric potentials, plasma temperatures, and current densities external to a neutralized ion engine in R-Z geometry. The present version assumes the beam ion current and density to be known and specified, and the neutralizing electrons to originate from a hot-wire ring surrounding the beam orifice. The plasma is treated as being resistive, with an electron relaxation time comparable to the plasma frequency. Together with the thermal and electrical boundary conditions described below and other straightforward engine parameters, these assumptions suffice to determine the required quantities. The ION code, written in ASCII FORTRAN for UNIVAC 1100 series computers, is designed to be run interactively, although it can also be run in batch mode. The input is free-format, and the output is mainly graphical, using the machine-independent graphics developed for the NASCAP code. The executive routine calls the code's major subroutines in user-specified order, and the code allows great latitude for restart and parameter change.

  11. Additional extensions to the NASCAP computer code, volume 1

    NASA Technical Reports Server (NTRS)

    Mandell, M. J.; Katz, I.; Stannard, P. R.

    1981-01-01

    Extensions and revisions to a computer code that comprehensively analyzes problems of spacecraft charging (NASCAP) are documented. Using a fully three dimensional approach, it can accurately predict spacecraft potentials under a variety of conditions. Among the extensions are a multiple electron/ion gun test tank capability, and the ability to model anisotropic and time dependent space environments. Also documented are a greatly extended MATCHG program and the preliminary version of NASCAP/LEO. The interactive MATCHG code was developed into an extremely powerful tool for the study of material-environment interactions. The NASCAP/LEO, a three dimensional code to study current collection under conditions of high voltages and short Debye lengths, was distributed for preliminary testing.

  12. Additive Manufacturing of Anatomical Models from Computed Tomography Scan Data.

    PubMed

    Gür, Y

    2014-12-01

    The purpose of the study presented here was to investigate the manufacturability of human anatomical models from Computed Tomography (CT) scan data via a 3D desktop printer which uses fused deposition modelling (FDM) technology. First, Digital Imaging and Communications in Medicine (DICOM) CT scan data were converted to 3D Standard Triangle Language (STL) format by using In Vaselius digital imaging program. Once this STL file is obtained, a 3D physical version of the anatomical model can be fabricated by a desktop 3D FDM printer. As a case study, a patient's skull CT scan data was considered, and a tangible version of the skull was manufactured by a 3D FDM desktop printer. During the 3D printing process, the skull was built using acrylonitrile-butadiene-styrene (ABS) co-polymer plastic. The printed model showed that the 3D FDM printing technology is able to fabricate anatomical models with high accuracy. As a result, the skull model can be used for preoperative surgical planning, medical training activities, implant design and simulation to show the potential of the FDM technology in medical field. It will also improve communication between medical stuff and patients. Current result indicates that a 3D desktop printer which uses FDM technology can be used to obtain accurate anatomical models.

  13. Computational calculation of equilibrium constants: addition to carbonyl compounds.

    PubMed

    Gómez-Bombarelli, Rafael; González-Pérez, Marina; Pérez-Prior, María Teresa; Calle, Emilio; Casado, Julio

    2009-10-22

    Hydration reactions are relevant for understanding many organic mechanisms. Since the experimental determination of hydration and hemiacetalization equilibrium constants is fairly complex, computational calculations now offer a useful alternative to experimental measurements. In this work, carbonyl hydration and hemiacetalization constants were calculated from the free energy differences between compounds in solution, using absolute and relative approaches. The following conclusions can be drawn: (i) The use of a relative approach in the calculation of hydration and hemiacetalization constants allows compensation of systematic errors in the solvation energies. (ii) On average, the methodology proposed here can predict hydration constants within +/- 0.5 log K(hyd) units for aldehydes. (iii) Hydration constants can be calculated for ketones and carboxylic acid derivatives within less than +/- 1.0 log K(hyd), on average, at the CBS-Q level of theory. (iv) The proposed methodology can predict hemiacetal formation constants accurately at the MP2 6-31++G(d,p) level using a common reference. If group references are used, the results obtained using the much cheaper DFT-B3LYP 6-31++G(d,p) level are almost as accurate. (v) In general, the best results are obtained if a common reference for all compounds is used. The use of group references improves the results at the lower levels of theory, but at higher levels, this becomes unnecessary.

  14. DOE's effort to reduce truck aerodynamic drag through joint experiments and computations.

    SciTech Connect

    Salari, Kambiz; Browand, Fred; Sreenivas, Kidambi; Pointer, W. David; Taylor, Lafayette; Pankajakshan, Ramesh; Whitfield, David; Plocher, Dennis; Ortega, Jason M.; Merzel, Tai; McCallen, Rose; Walker, Stephen M; Heineck, James T; Hassan, Basil; Roy, Christopher John; Storms, B.; Ross, James; Englar, Robert; Rubel, Mike; Leonard, Anthony; Radovich, Charles; Eastwood, Craig; Paschkewitz, John; Castellucci, Paul; DeChant, Lawrence Justin.

    2005-08-01

    Class 8 tractor-trailers are responsible for 11-12% of the total US consumption of petroleum. Overcoming aero drag represents 65% of energy expenditure at highway speeds. Most of the drag results from pressure differences and reducing highway speeds is very effective. The goal is to reduce aerodynamic drag by 25% which would translate to 12% improved fuel economy or 4,200 million gal/year. Objectives are: (1) In support of DOE's mission, provide guidance to industry in the reduction of aerodynamic drag; (2) To shorten and improve design process, establish a database of experimental, computational, and conceptual design information; (3) Demonstrate new drag-reduction techniques; and (4) Get devices on the road. Some accomplishments are: (1) Concepts developed/tested that exceeded 25% drag reduction goal; (2) Insight and guidelines for drag reduction provided to industry through computations and experiments; (3) Joined with industry in getting devices on the road and providing design concepts through virtual modeling and testing; and (4) International recognition achieved through open documentation and database.

  15. Computational and experimental studies of hydrodynamic instabilities and turbulent mixing (Review of NVIIEF efforts)

    SciTech Connect

    Andronov, V.A.; Zhidov, I.G.; Meskov, E.E.; Nevmerzhitskii, N.V.; Nikiforov, V.V.; Razin, A.N.; Rogatchev, V.G.; Tolshmyakov, A.I.; Yanilkin, Yu.V.

    1995-02-01

    This report describes an extensive program of investigations conducted at Arzamas-16 in Russia over the past several decades. The focus of the work is on material interface instability and the mixing of two materials. Part 1 of the report discusses analytical and computational studies of hydrodynamic instabilities and turbulent mixing. The EGAK codes are described and results are illustrated for several types of unstable flow. Semiempirical turbulence transport equations are derived for the mixing of two materials, and their capabilities are illustrated for several examples. Part 2 discusses the experimental studies that have been performed to investigate instabilities and turbulent mixing. Shock-tube and jelly techniques are described in considerable detail. Results are presented for many circumstances and configurations.

  16. Computational and experimental studies of hydrodynamic instabilities and turbulent mixing: Review of VNIIEF efforts. Summary report

    SciTech Connect

    Andronov, V.A.; Zhidov, I.G.; Meskov, E.E.; Nevmerzhitskii, N.V.; Nikiforov, V.V.; Razin, A.N.; Rogatchev, V.G.; Tolshmyakov, A.I.; Yanilkin, Y.V.

    1994-12-31

    The report presents the basic results of some calculations, theoretical and experimental efforts in the study of Rayleigh-Taylor, Kelvin-Helmholtz, Richtmyer-Meshkov instabilities and the turbulent mixing which is caused by their evolution. Since the late forties the VNIIEF has been conducting these investigations. This report is based on the data which were published in different times in Russian and foreign journals. The first part of the report deals with calculations an theoretical techniques for the description of hydrodynamic instabilities applied currently, as well as with the results of several individual problems and their comparison with the experiment. These methods can be divided into two types: direct numerical simulation methods and phenomenological methods. The first type includes the regular 2D and 3D gasdynamical techniques as well as the techniques based on small perturbation approximation and on incompressible liquid approximation. The second type comprises the techniques based on various phenomenological turbulence models. The second part of the report describes the experimental methods and cites the experimental results of Rayleigh-Taylor and Richtmyer-Meskov instability studies as well as of turbulent mixing. The applied methods were based on thin-film gaseous models, on jelly models and liquid layer models. The research was done for plane and cylindrical geometries. As drivers, the shock tubes of different designs were used as well as gaseous explosive mixtures, compressed air and electric wire explosions. The experimental results were applied in calculational-theoretical technique calibrations. The authors did not aim at covering all VNIIEF research done in this field of science. To a great extent the choice of the material depended on the personal contribution of the author in these studies.

  17. Evaluation of the computational effort for chromatic dispersion compensation in coherent optical PM-OFDM and PM-QAM systems.

    PubMed

    Poggiolini, P; Carena, A; Curri, V; Forghieri, F

    2009-02-02

    Recently, coherent-detection (CoD) polarization multiplexed (PM) transmission has attracted considerable interest, specifically as a possible solution for next-generation systems transmitting 100 Gb/s per channel and beyond. In this context, enabled by progress in ultra-fast digital signal processing (DSP) electronics, both multilevel phase/amplitude modulated formats (such as QAM) and orthogonal-frequency-division multiplexed (OFDM) formats have been proposed. One specific feature of DSP-supported CoD is the possibility of dealing with fiber chromatic dispersion (CD) electronically, either by post-filtering (PM-QAM) or by appropriately introducing symbol-duration redundancy (PM-OFDM). In both cases, ultra-long-haul fully uncompensated links seem to be possible. In this paper we estimate the computational effort required by CD compensation, when using the PM-QAM or PM-OFDM formats. Such effort, when expressed as number of operations per received bit, was found to be logarithmic with respect to link length, bit rate and fiber dispersion, for both classes of systems. We also found that PM-OFDM may have some advantage over PM-QAM, depending mostly on the over-sampling needed by the two systems. Asymptotically, for large channel memory and small over-sampling, the two systems tend to require the same CD-compensation computational effort. We also showed that the effort required by the mitigation of polarization-related effects can in principle be made small as compared to that of CD over long uncompensated links.

  18. Latent Tuberculosis: Models, Computational Efforts and the Pathogen’s Regulatory Mechanisms during Dormancy

    PubMed Central

    Magombedze, Gesham; Dowdy, David; Mulder, Nicola

    2013-01-01

    Latent tuberculosis is a clinical syndrome that occurs after an individual has been exposed to the Mycobacterium tuberculosis (Mtb) Bacillus, the infection has been established and an immune response has been generated to control the pathogen and force it into a quiescent state. Mtb can exit this quiescent state where it is unresponsive to treatment and elusive to the immune response, and enter a rapid replicating state, hence causing infection reactivation. It remains a gray area to understand how the pathogen causes a persistent infection and it is unclear whether the organism will be in a slow replicating state or a dormant non-replicating state. The ability of the pathogen to adapt to changing host immune response mechanisms, in which it is exposed to hypoxia, low pH, nitric oxide (NO), nutrient starvation, and several other anti-microbial effectors, is associated with a high metabolic plasticity that enables it to metabolize under these different conditions. Adaptive gene regulatory mechanisms are thought to coordinate how the pathogen changes their metabolic pathways through mechanisms that sense changes in oxygen tension and other stress factors, hence stimulating the pathogen to make necessary adjustments to ensure survival. Here, we review studies that give insights into latency/dormancy regulatory mechanisms that enable infection persistence and pathogen adaptation to different stress conditions. We highlight what mathematical and computational models can do and what they should do to enhance our current understanding of TB latency. PMID:25023946

  19. Additives

    NASA Technical Reports Server (NTRS)

    Smalheer, C. V.

    1973-01-01

    The chemistry of lubricant additives is discussed to show what the additives are chemically and what functions they perform in the lubrication of various kinds of equipment. Current theories regarding the mode of action of lubricant additives are presented. The additive groups discussed include the following: (1) detergents and dispersants, (2) corrosion inhibitors, (3) antioxidants, (4) viscosity index improvers, (5) pour point depressants, and (6) antifouling agents.

  20. Observed differences in upper extremity forces, muscle efforts, postures, velocities and accelerations across computer activities in a field study of office workers.

    PubMed

    Bruno Garza, J L; Eijckelhof, B H W; Johnson, P W; Raina, S M; Rynell, P W; Huysmans, M A; van Dieën, J H; van der Beek, A J; Blatter, B M; Dennerlein, J T

    2012-01-01

    This study, a part of the PRedicting Occupational biomechanics in OFfice workers (PROOF) study, investigated whether there are differences in field-measured forces, muscle efforts, postures, velocities and accelerations across computer activities. These parameters were measured continuously for 120 office workers performing their own work for two hours each. There were differences in nearly all forces, muscle efforts, postures, velocities and accelerations across keyboard, mouse and idle activities. Keyboard activities showed a 50% increase in the median right trapezius muscle effort when compared to mouse activities. Median shoulder rotation changed from 25 degrees internal rotation during keyboard use to 15 degrees external rotation during mouse use. Only keyboard use was associated with median ulnar deviations greater than 5 degrees. Idle activities led to the greatest variability observed in all muscle efforts and postures measured. In future studies, measurements of computer activities could be used to provide information on the physical exposures experienced during computer use. Practitioner Summary: Computer users may develop musculoskeletal disorders due to their force, muscle effort, posture and wrist velocity and acceleration exposures during computer use. We report that many physical exposures are different across computer activities. This information may be used to estimate physical exposures based on patterns of computer activities over time.

  1. CHARMM additive and polarizable force fields for biophysics and computer-aided drug design

    PubMed Central

    Vanommeslaeghe, K.

    2014-01-01

    Background Molecular Mechanics (MM) is the method of choice for computational studies of biomolecular systems owing to its modest computational cost, which makes it possible to routinely perform molecular dynamics (MD) simulations on chemical systems of biophysical and biomedical relevance. Scope of Review As one of the main factors limiting the accuracy of MD results is the empirical force field used, the present paper offers a review of recent developments in the CHARMM additive force field, one of the most popular bimolecular force fields. Additionally, we present a detailed discussion of the CHARMM Drude polarizable force field, anticipating a growth in the importance and utilization of polarizable force fields in the near future. Throughout the discussion emphasis is placed on the force fields’ parametrization philosophy and methodology. Major Conclusions Recent improvements in the CHARMM additive force field are mostly related to newly found weaknesses in the previous generation of additive force fields. Beyond the additive approximation is the newly available CHARMM Drude polarizable force field, which allows for MD simulations of up to 1 microsecond on proteins, DNA, lipids and carbohydrates. General Significance Addressing the limitations ensures the reliability of the new CHARMM36 additive force field for the types of calculations that are presently coming into routine computational reach while the availability of the Drude polarizable force fields offers a model that is an inherently more accurate model of the underlying physical forces driving macromolecular structures and dynamics. PMID:25149274

  2. Utilizing a Collaborative Cross Number Puzzle Game to Develop the Computing Ability of Addition and Subtraction

    ERIC Educational Resources Information Center

    Chen, Yen-Hua; Looi, Chee-Kit; Lin, Chiu-Pin; Shao, Yin-Juan; Chan, Tak-Wai

    2012-01-01

    While addition and subtraction is a key mathematical skill for young children, a typical activity for them in classrooms involves doing repetitive arithmetic calculation exercises. In this study, we explore a collaborative way for students to learn these skills in a technology-enabled way with wireless computers. Two classes, comprising a total of…

  3. Districts' Efforts for Data Use and Computer Data Systems: The Role of Sensemaking in System Use and Implementation

    ERIC Educational Resources Information Center

    Cho, Vincent; Wayman, Jeffrey C.

    2014-01-01

    Background: Increasingly, teachers and other educators are expected to leverage data in making educational decisions. Effective data use is difficult, if not impossible, without computer data systems. Nonetheless, these systems may be underused or even rejected by teachers. One potential explanation for such troubles may relate to how teachers…

  4. Designing and Implementing a Faculty Internet Workshop: A Collaborative Effort of Academic Computing Services and the University Library.

    ERIC Educational Resources Information Center

    Bradford, Jane T.; And Others

    1996-01-01

    Academic Computing Services staff and University librarians at Stetson University (DeLand, Florida) designed and implemented a three-day Internet workshop for interested faculty. The workshop included both hands-on lab sessions and discussions covering e-mail, telnet, ftp, Gopher, and World Wide Web. The planning, preparation of the lab and…

  5. Addition of flexible body option to the TOLA computer program, part 1

    NASA Technical Reports Server (NTRS)

    Dick, J. W.; Benda, B. J.

    1975-01-01

    This report describes a flexible body option that was developed and added to the Takeoff and Landing Analysis (TOLA) computer program. The addition of the flexible body option to TOLA allows it to be used to study essentially any conventional type airplane in the ground operating environment. It provides the capability to predict the total motion of selected points on the analytical methods incorporated in the program and operating instructions for the option are described. A program listing is included along with several example problems to aid in interpretation of the operating instructions and to illustrate program usage.

  6. Computational study of the rate constants and free energies of intramolecular radical addition to substituted anilines

    PubMed Central

    Seddiqzai, Meriam; Dahmen, Tobias; Sure, Rebecca

    2013-01-01

    Summary The intramolecular radical addition to aniline derivatives was investigated by DFT calculations. The computational methods were benchmarked by comparing the calculated values of the rate constant for the 5-exo cyclization of the hexenyl radical with the experimental values. The dispersion-corrected PW6B95-D3 functional provided very good results with deviations for the free activation barrier compared to the experimental values of only about 0.5 kcal mol−1 and was therefore employed in further calculations. Corrections for intramolecular London dispersion and solvation effects in the quantum chemical treatment are essential to obtain consistent and accurate theoretical data. For the investigated radical addition reaction it turned out that the polarity of the molecules is important and that a combination of electrophilic radicals with preferably nucleophilic arenes results in the highest rate constants. This is opposite to the Minisci reaction where the radical acts as nucleophile and the arene as electrophile. The substitution at the N-atom of the aniline is crucial. Methyl substitution leads to slower addition than phenyl substitution. Carbamates as substituents are suitable only when the radical center is not too electrophilic. No correlations between free reaction barriers and energies (ΔG ‡ and ΔG R) are found. Addition reactions leading to indanes or dihydrobenzofurans are too slow to be useful synthetically. PMID:24062821

  7. A comparison of the additional protocols of the five nuclear weapon states and the ensuing safeguards benefits to international nonproliferation efforts

    SciTech Connect

    Uribe, Eva C; Sandoval, M Analisa; Sandoval, Marisa N; Boyer, Brian D; Leitch, Rosalyn M

    2009-01-01

    With the 6 January 2009 entry into force of the Additional Protocol by the United States of America, all five declared Nuclear Weapon States that are part of the Nonproliferation Treaty have signed, ratified, and put into force the Additional Protocol. This paper makes a comparison of the strengths and weaknesses of the five Additional Protocols in force by the five Nuclear Weapon States with respect to the benefits to international nonproliferation aims. This paper also documents the added safeguards burden to the five declared Nuclear Weapon States that these Additional Protocols put on the states with respect to access to their civilian nuclear programs and the hosting of complementary access activities as part of the Additional Protocol.

  8. Effortful echolalia.

    PubMed

    Hadano, K; Nakamura, H; Hamanaka, T

    1998-02-01

    We report three cases of effortful echolalia in patients with cerebral infarction. The clinical picture of speech disturbance is associated with Type 1 Transcortical Motor Aphasia (TCMA, Goldstein, 1915). The patients always spoke nonfluently with loss of speech initiative, dysarthria, dysprosody, agrammatism, and increased effort and were unable to repeat sentences longer than those containing four or six words. In conversation, they first repeated a few words spoken to them, and then produced self initiated speech. The initial repetition as well as the subsequent self initiated speech, which were realized equally laboriously, can be regarded as mitigated echolalia (Pick, 1924). They were always aware of their own echolalia and tried to control it without effect. These cases demonstrate that neither the ability to repeat nor fluent speech are always necessary for echolalia. The possibility that a lesion in the left medial frontal lobe, including the supplementary motor area, plays an important role in effortful echolalia is discussed.

  9. PAH growth initiated by propargyl addition: mechanism development and computational kinetics.

    PubMed

    Raj, Abhijeet; Al Rashidi, Mariam J; Chung, Suk Ho; Sarathy, S Mani

    2014-04-24

    Polycyclic aromatic hydrocarbon (PAH) growth is known to be the principal pathway to soot formation during fuel combustion, as such, a physical understanding of the PAH growth mechanism is needed to effectively assess, predict, and control soot formation in flames. Although the hydrogen abstraction C2H2 addition (HACA) mechanism is believed to be the main contributor to PAH growth, it has been shown to under-predict some of the experimental data on PAHs and soot concentrations in flames. This article presents a submechanism of PAH growth that is initiated by propargyl (C3H3) addition onto naphthalene (A2) and the naphthyl radical. C3H3 has been chosen since it is known to be a precursor of benzene in combustion and has appreciable concentrations in flames. This mechanism has been developed up to the formation of pyrene (A4), and the temperature-dependent kinetics of each elementary reaction has been determined using density functional theory (DFT) computations at the B3LYP/6-311++G(d,p) level of theory and transition state theory (TST). H-abstraction, H-addition, H-migration, β-scission, and intramolecular addition reactions have been taken into account. The energy barriers of the two main pathways (H-abstraction and H-addition) were found to be relatively small if not negative, whereas the energy barriers of the other pathways were in the range of (6-89 kcal·mol(-1)). The rates reported in this study may be extrapolated to larger PAH molecules that have a zigzag site similar to that in naphthalene, and the mechanism presented herein may be used as a complement to the HACA mechanism to improve prediction of PAH and soot formation.

  10. Laser powder bed fusion additive manufacturing of metals; physics, computational, and materials challenges

    NASA Astrophysics Data System (ADS)

    King, W. E.; Anderson, A. T.; Ferencz, R. M.; Hodge, N. E.; Kamath, C.; Khairallah, S. A.; Rubenchik, A. M.

    2015-12-01

    The production of metal parts via laser powder bed fusion additive manufacturing is growing exponentially. However, the transition of this technology from production of prototypes to production of critical parts is hindered by a lack of confidence in the quality of the part. Confidence can be established via a fundamental understanding of the physics of the process. It is generally accepted that this understanding will be increasingly achieved through modeling and simulation. However, there are significant physics, computational, and materials challenges stemming from the broad range of length and time scales and temperature ranges associated with the process. In this paper, we review the current state of the art and describe the challenges that need to be met to achieve the desired fundamental understanding of the physics of the process.

  11. Laser powder bed fusion additive manufacturing of metals; physics, computational, and materials challenges

    SciTech Connect

    King, W. E.; Anderson, A. T.; Ferencz, R. M.; Hodge, N. E.; Kamath, C.; Khairallah, S. A.; Rubencik, A. M.

    2015-12-29

    The production of metal parts via laser powder bed fusion additive manufacturing is growing exponentially. However, the transition of this technology from production of prototypes to production of critical parts is hindered by a lack of confidence in the quality of the part. Confidence can be established via a fundamental understanding of the physics of the process. It is generally accepted that this understanding will be increasingly achieved through modeling and simulation. However, there are significant physics, computational, and materials challenges stemming from the broad range of length and time scales and temperature ranges associated with the process. In this study, we review the current state of the art and describe the challenges that need to be met to achieve the desired fundamental understanding of the physics of the process.

  12. Additive Manufacturing and High-Performance Computing: a Disruptive Latent Technology

    NASA Astrophysics Data System (ADS)

    Goodwin, Bruce

    2015-03-01

    This presentation will discuss the relationship between recent advances in Additive Manufacturing (AM) technology, High-Performance Computing (HPC) simulation and design capabilities, and related advances in Uncertainty Quantification (UQ), and then examines their impacts upon national and international security. The presentation surveys how AM accelerates the fabrication process, while HPC combined with UQ provides a fast track for the engineering design cycle. The combination of AM and HPC/UQ almost eliminates the engineering design and prototype iterative cycle, thereby dramatically reducing cost of production and time-to-market. These methods thereby present significant benefits for US national interests, both civilian and military, in an age of austerity. Finally, considering cyber security issues and the advent of the ``cloud,'' these disruptive, currently latent technologies may well enable proliferation and so challenge both nuclear and non-nuclear aspects of international security.

  13. Laser powder bed fusion additive manufacturing of metals; physics, computational, and materials challenges

    SciTech Connect

    King, W. E.; Anderson, A. T.; Ferencz, R. M.; Hodge, N. E.; Khairallah, S. A.; Kamath, C.; Rubenchik, A. M.

    2015-12-15

    The production of metal parts via laser powder bed fusion additive manufacturing is growing exponentially. However, the transition of this technology from production of prototypes to production of critical parts is hindered by a lack of confidence in the quality of the part. Confidence can be established via a fundamental understanding of the physics of the process. It is generally accepted that this understanding will be increasingly achieved through modeling and simulation. However, there are significant physics, computational, and materials challenges stemming from the broad range of length and time scales and temperature ranges associated with the process. In this paper, we review the current state of the art and describe the challenges that need to be met to achieve the desired fundamental understanding of the physics of the process.

  14. Laser powder bed fusion additive manufacturing of metals; physics, computational, and materials challenges

    DOE PAGES

    King, W. E.; Anderson, A. T.; Ferencz, R. M.; ...

    2015-12-29

    The production of metal parts via laser powder bed fusion additive manufacturing is growing exponentially. However, the transition of this technology from production of prototypes to production of critical parts is hindered by a lack of confidence in the quality of the part. Confidence can be established via a fundamental understanding of the physics of the process. It is generally accepted that this understanding will be increasingly achieved through modeling and simulation. However, there are significant physics, computational, and materials challenges stemming from the broad range of length and time scales and temperature ranges associated with the process. In thismore » study, we review the current state of the art and describe the challenges that need to be met to achieve the desired fundamental understanding of the physics of the process.« less

  15. Documentary effort.

    PubMed

    2006-01-01

    This spring, Virtua Health, the largest health system in Southern New Jersey, launched an innovative campaign aimed at raising overall awareness of its facilities by documenting real-life patients undergoing a variety of experiences (e.g., breast cancer, high-risk pregnancy, spine surgery, and minimally-invasive knee replacement surgery). The effort, called "The Virtua Experience" became a 30-minute hospital documentary that aired on Philadelphia's NBC affiliate this summer.

  16. Computation of octanol-water partition coefficients by guiding an additive model with knowledge.

    PubMed

    Cheng, Tiejun; Zhao, Yuan; Li, Xun; Lin, Fu; Xu, Yong; Zhang, Xinglong; Li, Yan; Wang, Renxiao; Lai, Luhua

    2007-01-01

    We have developed a new method, i.e., XLOGP3, for logP computation. XLOGP3 predicts the logP value of a query compound by using the known logP value of a reference compound as a starting point. The difference in the logP values of the query compound and the reference compound is then estimated by an additive model. The additive model implemented in XLOGP3 uses a total of 87 atom/group types and two correction factors as descriptors. It is calibrated on a training set of 8199 organic compounds with reliable logP data through a multivariate linear regression analysis. For a given query compound, the compound showing the highest structural similarity in the training set will be selected as the reference compound. Structural similarity is quantified based on topological torsion descriptors. XLOGP3 has been tested along with its predecessor, i.e., XLOGP2, as well as several popular logP methods on two independent test sets: one contains 406 small-molecule drugs approved by the FDA and the other contains 219 oligopeptides. On both test sets, XLOGP3 produces more accurate predictions than most of the other methods with average unsigned errors of 0.24-0.51 units. Compared to conventional additive methods, XLOGP3 does not rely on an extensive classification of fragments and correction factors in order to improve accuracy. It is also able to utilize the ever-increasing experimentally measured logP data more effectively.

  17. Using additive manufacturing in accuracy evaluation of reconstructions from computed tomography.

    PubMed

    Smith, Erin J; Anstey, Joseph A; Venne, Gabriel; Ellis, Randy E

    2013-05-01

    Bone models derived from patient imaging and fabricated using additive manufacturing technology have many potential uses including surgical planning, training, and research. This study evaluated the accuracy of bone surface reconstruction of two diarthrodial joints, the hip and shoulder, from computed tomography. Image segmentation of the tomographic series was used to develop a three-dimensional virtual model, which was fabricated using fused deposition modelling. Laser scanning was used to compare cadaver bones, printed models, and intermediate segmentations. The overall bone reconstruction process had a reproducibility of 0.3 ± 0.4 mm. Production of the model had an accuracy of 0.1 ± 0.1 mm, while the segmentation had an accuracy of 0.3 ± 0.4 mm, indicating that segmentation accuracy was the key factor in reconstruction. Generally, the shape of the articular surfaces was reproduced accurately, with poorer accuracy near the periphery of the articular surfaces, particularly in regions with periosteum covering and where osteophytes were apparent.

  18. Role of information systems in controlling costs: the electronic medical record (EMR) and the high-performance computing and communications (HPCC) efforts

    NASA Astrophysics Data System (ADS)

    Kun, Luis G.

    1994-12-01

    On October 18, 1991, the IEEE-USA produced an entity statement which endorsed the vital importance of the High Performance Computer and Communications Act of 1991 (HPCC) and called for the rapid implementation of all its elements. Efforts are now underway to develop a Computer Based Patient Record (CBPR), the National Information Infrastructure (NII) as part of the HPCC, and the so-called `Patient Card'. Multiple legislative initiatives which address these and related information technology issues are pending in Congress. Clearly, a national information system will greatly affect the way health care delivery is provided to the United States public. Timely and reliable information represents a critical element in any initiative to reform the health care system as well as to protect and improve the health of every person. Appropriately used, information technologies offer a vital means of improving the quality of patient care, increasing access to universal care and lowering overall costs within a national health care program. Health care reform legislation should reflect increased budgetary support and a legal mandate for the creation of a national health care information system by: (1) constructing a National Information Infrastructure; (2) building a Computer Based Patient Record System; (3) bringing the collective resources of our National Laboratories to bear in developing and implementing the NII and CBPR, as well as a security system with which to safeguard the privacy rights of patients and the physician-patient privilege; and (4) utilizing Government (e.g. DOD, DOE) capabilities (technology and human resources) to maximize resource utilization, create new jobs and accelerate technology transfer to address health care issues.

  19. Addition of flexible body option to the TOLA computer program. Part 2: User and programmer documentation

    NASA Technical Reports Server (NTRS)

    Dick, J. W.; Benda, B. J.

    1975-01-01

    User and programmer oriented documentation for the flexible body option of the Takeoff and Landing Analysis (TOLA) computer program are provided. The user information provides sufficient knowledge of the development and use of the option to enable the engineering user to successfully operate the modified program and understand the results. The programmer's information describes the option structure and logic enabling a programmer to make major revisions to this part of the TOLA computer program.

  20. A Scientific Workflow Used as a Computational Tool to Assess the Response of the Californian San Joaquin River to Flow Restoration Efforts

    NASA Astrophysics Data System (ADS)

    Villamizar, S. R.; Gil, Y.; Szekely, P.; Ratnakar, V.; Gupta, S.; Muslea, M.; Silva, F.; Harmon, T.

    2011-12-01

    The San Joaquin River (SJR) restoration effort began in October 2009 with the onset of federally mandated continuous flow. A key objective of the effort is to restore and maintain fish populations in the main stem of the San Joaquin River, from below the Friant Dam to the confluence of the Merced River. In addition to the renewed flows, the restoration effort has brought about several upgraded and new water quality monitoring stations equipped with dissolved oxygen (DO) and temperature sensors. As the SJR response to the restoration efforts will be dictated by a complex combination of hydrodynamic and biogeochemical processes, we propose monitoring whole-stream metabolism as an integrative ecological indicator. Here, we develop and test a near-real time scientific workflow to facilitate the observation of the spatio-temporal distribution of whole-stream metabolism estimates using available monitoring station flow and water quality data. The scientific objective is to identify correlations between whole-stream metabolism estimates and the seasonally variable flow and flow disturbances (e.g., flood-control releases), which are the primary driver of stream ecosystems. To accomplish this requires overcoming technical challenges in terms of both data collection and data analysis because (1) the information required for this multi-site, long-term study, originates from different sources with the implication of different associated properties (data integrity, sampling intervals, units), and (2) the variability of the interim flows requires adaptive model selection within the framework of the metabolism calculations. These challenges are addressed by using a scientific workflow in which semantic metadata is generated as the data is prepared and then subsequently used to select and configure models, effectively customizing them to the current data. Data preparation involves the extraction, cleaning, normalization and integration of the data coming from sensors and third

  1. Can Computer-Assisted Discovery Learning Foster First Graders' Fluency with the Most Basic Addition Combinations?

    ERIC Educational Resources Information Center

    Baroody, Arthur J.; Eiland, Michael D.; Purpura, David J.; Reid, Erin E.

    2013-01-01

    In a 9-month training experiment, 64 first graders with a risk factor were randomly assigned to computer-assisted structured discovery of the add-1 rule (e.g., the sum of 7 + 1 is the number after "seven" when we count), unstructured discovery learning of this regularity, or an active-control group. Planned contrasts revealed that the…

  2. The Effects of Computer-Assisted Instruction on Student Achievement in Addition and Subtraction at First Grade Level.

    ERIC Educational Resources Information Center

    Spivey, Patsy M.

    This study was conducted to determine whether the traditional classroom approach to instruction involving the addition and subtraction of number facts (digits 0-6) is more or less effective than the traditional classroom approach plus a commercially-prepared computer game. A pretest-posttest control group design was used with two groups of first…

  3. 17 CFR Appendix B to Part 4 - Adjustments for Additions and Withdrawals in the Computation of Rate of Return

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Adjustments for Additions and Withdrawals in the Computation of Rate of Return B Appendix B to Part 4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION COMMODITY POOL OPERATORS AND COMMODITY TRADING ADVISORS Pt. 4, App....

  4. 17 CFR Appendix B to Part 4 - Adjustments for Additions and Withdrawals in the Computation of Rate of Return

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Adjustments for Additions and Withdrawals in the Computation of Rate of Return B Appendix B to Part 4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION COMMODITY POOL OPERATORS AND COMMODITY TRADING ADVISORS Pt. 4, App....

  5. 17 CFR Appendix B to Part 4 - Adjustments for Additions and Withdrawals in the Computation of Rate of Return

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Adjustments for Additions and Withdrawals in the Computation of Rate of Return B Appendix B to Part 4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION COMMODITY POOL OPERATORS AND COMMODITY TRADING ADVISORS Pt. 4, App....

  6. 17 CFR Appendix B to Part 4 - Adjustments for Additions and Withdrawals in the Computation of Rate of Return

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Adjustments for Additions and Withdrawals in the Computation of Rate of Return B Appendix B to Part 4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION COMMODITY POOL OPERATORS AND COMMODITY TRADING ADVISORS Pt. 4, App....

  7. 17 CFR Appendix B to Part 4 - Adjustments for Additions and Withdrawals in the Computation of Rate of Return

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 1 2014-04-01 2014-04-01 false Adjustments for Additions and Withdrawals in the Computation of Rate of Return B Appendix B to Part 4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION COMMODITY POOL OPERATORS AND COMMODITY TRADING ADVISORS Pt. 4, App....

  8. Subsonic flutter analysis addition to NASTRAN. [for use with CDC 6000 series digital computers

    NASA Technical Reports Server (NTRS)

    Doggett, R. V., Jr.; Harder, R. L.

    1973-01-01

    A subsonic flutter analysis capability has been developed for NASTRAN, and a developmental version of the program has been installed on the CDC 6000 series digital computers at the Langley Research Center. The flutter analysis is of the modal type, uses doublet lattice unsteady aerodynamic forces, and solves the flutter equations by using the k-method. Surface and one-dimensional spline functions are used to transform from the aerodynamic degrees of freedom to the structural degrees of freedom. Some preliminary applications of the method to a beamlike wing, a platelike wing, and a platelike wing with a folded tip are compared with existing experimental and analytical results.

  9. Postprocessing of Voxel-Based Topologies for Additive Manufacturing Using the Computational Geometry Algorithms Library (CGAL)

    DTIC Science & Technology

    2015-06-01

    that a structure is built up by layers. Typically, additive manufacturing devices (3-dimensional [3-D] printers , e.g.), use the stereolithography (STL...begin with a standard, voxel-based topology optimization scheme and end with an STL file, ready for use in a 3-D printer or other additive manufacturing...S, Yvinec M. Cgal 4.6 - 3d alpha shapes. 2015 [accessed 2015 May 18]. http://doc.cgal.org/latest/Alpha_shapes_3/index.html#Chapter_3D_ Alpha_Shapes

  10. Addition of higher order plate and shell elements into NASTRAN computer program

    NASA Technical Reports Server (NTRS)

    Narayanaswami, R.; Goglia, G. L.

    1976-01-01

    Two higher order plate elements, the linear strain triangular membrane element and the quintic bending element, along with a shallow shell element, suitable for inclusion into the NASTRAN (NASA Structural Analysis) program are described. Additions to the NASTRAN Theoretical Manual, Users' Manual, Programmers' Manual and the NASTRAN Demonstration Problem Manual, for inclusion of these elements into the NASTRAN program are also presented.

  11. Addition of visual noise boosts evoked potential-based brain-computer interface

    PubMed Central

    Xie, Jun; Xu, Guanghua; Wang, Jing; Zhang, Sicong; Zhang, Feng; Li, Yeping; Han, Chengcheng; Li, Lili

    2014-01-01

    Although noise has a proven beneficial role in brain functions, there have not been any attempts on the dedication of stochastic resonance effect in neural engineering applications, especially in researches of brain-computer interfaces (BCIs). In our study, a steady-state motion visual evoked potential (SSMVEP)-based BCI with periodic visual stimulation plus moderate spatiotemporal noise can achieve better offline and online performance due to enhancement of periodic components in brain responses, which was accompanied by suppression of high harmonics. Offline results behaved with a bell-shaped resonance-like functionality and 7–36% online performance improvements can be achieved when identical visual noise was adopted for different stimulation frequencies. Using neural encoding modeling, these phenomena can be explained as noise-induced input-output synchronization in human sensory systems which commonly possess a low-pass property. Our work demonstrated that noise could boost BCIs in addressing human needs. PMID:24828128

  12. Efficient method for computing the maximum-likelihood quantum state from measurements with additive Gaussian noise.

    PubMed

    Smolin, John A; Gambetta, Jay M; Smith, Graeme

    2012-02-17

    We provide an efficient method for computing the maximum-likelihood mixed quantum state (with density matrix ρ) given a set of measurement outcomes in a complete orthonormal operator basis subject to Gaussian noise. Our method works by first changing basis yielding a candidate density matrix μ which may have nonphysical (negative) eigenvalues, and then finding the nearest physical state under the 2-norm. Our algorithm takes at worst O(d(4)) for the basis change plus O(d(3)) for finding ρ where d is the dimension of the quantum state. In the special case where the measurement basis is strings of Pauli operators, the basis change takes only O(d(3)) as well. The workhorse of the algorithm is a new linear-time method for finding the closest probability distribution (in Euclidean distance) to a set of real numbers summing to one.

  13. Large Advanced Space Systems (LASS) computer-aided design program additions

    NASA Technical Reports Server (NTRS)

    Farrell, C. E.

    1982-01-01

    The LSS preliminary and conceptual design requires extensive iteractive analysis because of the effects of structural, thermal, and control intercoupling. A computer aided design program that will permit integrating and interfacing of required large space system (LSS) analyses is discussed. The primary objective of this program is the implementation of modeling techniques and analysis algorithms that permit interactive design and tradeoff studies of LSS concepts. Eight software modules were added to the program. The existing rigid body controls module was modified to include solar pressure effects. The new model generator modules and appendage synthesizer module are integrated (interfaced) to permit interactive definition and generation of LSS concepts. The mass properties module permits interactive specification of discrete masses and their locations. The other modules permit interactive analysis of orbital transfer requirements, antenna primary beam n, and attitude control requirements.

  14. Enantioselective conjugate addition of nitro compounds to α,β-unsaturated ketones: an experimental and computational study.

    PubMed

    Manzano, Rubén; Andrés, José M; Álvarez, Rosana; Muruzábal, María D; de Lera, Ángel R; Pedrosa, Rafael

    2011-05-16

    A series of chiral thioureas derived from easily available diamines, prepared from α-amino acids, have been tested as catalysts in the enantioselective Michael additions of nitroalkanes to α,β-unsaturated ketones. The best results are obtained with the bifunctional catalyst prepared from L-valine. This thiourea promotes the reaction with high enantioselectivities and chemical yields for aryl/vinyl ketones, but the enantiomeric ratio for alkyl/vinyl derivatives is very modest. The addition of substituted nitromethanes led to the corresponding adducts with excellent enantioselectivity but very poor diastereoselectivity. Evidence for the isomerization of the addition products has been obtained from the reaction of chalcone with [D(3)]nitromethane, which shows that the final addition products epimerize under the reaction conditions. The epimerization explains the low diastereoselectivity observed in the formation of adducts with two adjacent tertiary stereocenters. Density functional studies of the transition structures corresponding to two alternative activation modes of the nitroalkanes and α,β-unsaturated ketones by the bifunctional organocatalyst have been carried out at the B3LYP/3-21G* level. The computations are consistent with a reaction model involving the Michael addition of the thiourea-activated nitronate to the ketone activated by the protonated amine of the organocatalyst. The enantioselectivities predicted by the computations are consistent with the experimental values obtained for aryl- and alkyl-substituted α,β-unsaturated ketones.

  15. Definition and computation of intermolecular contact in liquids using additively weighted Voronoi tessellation.

    PubMed

    Isele-Holder, Rolf E; Rabideau, Brooks D; Ismail, Ahmed E

    2012-05-10

    We present a definition of intermolecular surface contact by applying weighted Voronoi tessellations to configurations of various organic liquids and water obtained from molecular dynamics simulations. This definition of surface contact is used to link the COSMO-RS model and molecular dynamics simulations. We demonstrate that additively weighted tessellation is the superior tessellation type to define intermolecular surface contact. Furthermore, we fit a set of weights for the elements C, H, O, N, F, and S for this tessellation type to obtain optimal agreement between the models. We use these radii to successfully predict contact statistics for compounds that were excluded from the fit and mixtures. The observed agreement between contact statistics from COSMO-RS and molecular dynamics simulations confirms the capability of the presented method to describe intermolecular contact. Furthermore, we observe that increasing polarity of the surfaces of the examined molecules leads to weaker agreement in the contact statistics. This is especially pronounced for pure water.

  16. Computer Use Planning: A Case Study of a School District's Long-Range Planning Efforts. Paper and Report Series No. 95.

    ERIC Educational Resources Information Center

    Gray, Peter J.; Rawers, Lois J.

    Based on a case study of a large northwestern suburban school district's initial attempts to establish policy for school use of computers, this report addresses such general questions as how school districts develop policies for instructional and administrative uses of computers, how school policy formation committees function, and how their…

  17. International aerospaceplane efforts

    NASA Technical Reports Server (NTRS)

    Lindley, Charles A.

    1992-01-01

    Although the U.S. began the first reusable space booster effort in the late 1950's, it is no longer an exclusive field. All of the technologically advanced nations, and several groups of nations, have one or more reusable booster efforts in progress. A listing of the entries in the field is presented. The list is somewhat misleading, because it includes both fully reusable and partially reusable boosters, both manned and unmanned, and both flight test and operational proposals. Additionally, not all of the projects are funded, and only a few of the projects will survive. The most likely candidates are the following: France/ESA, Germany/ESA, Great Britain/ESA/(USSR), USSR(past), and Japan. A discussion of the preceding projects is provided.

  18. Neurocomputational mechanisms underlying subjective valuation of effort costs

    PubMed Central

    Giehl, Kathrin; Sillence, Annie

    2017-01-01

    In everyday life, we have to decide whether it is worth exerting effort to obtain rewards. Effort can be experienced in different domains, with some tasks requiring significant cognitive demand and others being more physically effortful. The motivation to exert effort for reward is highly subjective and varies considerably across the different domains of behaviour. However, very little is known about the computational or neural basis of how different effort costs are subjectively weighed against rewards. Is there a common, domain-general system of brain areas that evaluates all costs and benefits? Here, we used computational modelling and functional magnetic resonance imaging (fMRI) to examine the mechanisms underlying value processing in both the cognitive and physical domains. Participants were trained on two novel tasks that parametrically varied either cognitive or physical effort. During fMRI, participants indicated their preferences between a fixed low-effort/low-reward option and a variable higher-effort/higher-reward offer for each effort domain. Critically, reward devaluation by both cognitive and physical effort was subserved by a common network of areas, including the dorsomedial and dorsolateral prefrontal cortex, the intraparietal sulcus, and the anterior insula. Activity within these domain-general areas also covaried negatively with reward and positively with effort, suggesting an integration of these parameters within these areas. Additionally, the amygdala appeared to play a unique, domain-specific role in processing the value of rewards associated with cognitive effort. These results are the first to reveal the neurocomputational mechanisms underlying subjective cost–benefit valuation across different domains of effort and provide insight into the multidimensional nature of motivation. PMID:28234892

  19. Neurocomputational mechanisms underlying subjective valuation of effort costs.

    PubMed

    Chong, Trevor T-J; Apps, Matthew; Giehl, Kathrin; Sillence, Annie; Grima, Laura L; Husain, Masud

    2017-02-01

    In everyday life, we have to decide whether it is worth exerting effort to obtain rewards. Effort can be experienced in different domains, with some tasks requiring significant cognitive demand and others being more physically effortful. The motivation to exert effort for reward is highly subjective and varies considerably across the different domains of behaviour. However, very little is known about the computational or neural basis of how different effort costs are subjectively weighed against rewards. Is there a common, domain-general system of brain areas that evaluates all costs and benefits? Here, we used computational modelling and functional magnetic resonance imaging (fMRI) to examine the mechanisms underlying value processing in both the cognitive and physical domains. Participants were trained on two novel tasks that parametrically varied either cognitive or physical effort. During fMRI, participants indicated their preferences between a fixed low-effort/low-reward option and a variable higher-effort/higher-reward offer for each effort domain. Critically, reward devaluation by both cognitive and physical effort was subserved by a common network of areas, including the dorsomedial and dorsolateral prefrontal cortex, the intraparietal sulcus, and the anterior insula. Activity within these domain-general areas also covaried negatively with reward and positively with effort, suggesting an integration of these parameters within these areas. Additionally, the amygdala appeared to play a unique, domain-specific role in processing the value of rewards associated with cognitive effort. These results are the first to reveal the neurocomputational mechanisms underlying subjective cost-benefit valuation across different domains of effort and provide insight into the multidimensional nature of motivation.

  20. Turbulence computations with 3-D small-scale additive turbulent decomposition and data-fitting using chaotic map combinations

    SciTech Connect

    Mukerji, Sudip

    1997-01-01

    Although the equations governing turbulent fluid flow, the Navier-Stokes (N.S.) equations, have been known for well over a century and there is a clear technological necessity in obtaining solutions to these equations, turbulence remains one of the principal unsolved problems in physics today. It is still not possible to make accurate quantitative predictions about turbulent flows without relying heavily on empirical data. In principle, it is possible to obtain turbulent solutions from a direct numerical simulation (DNS) of the N.-S. equations. The author first provides a brief introduction to the dynamics of turbulent flows. The N.-S. equations which govern fluid flow, are described thereafter. Then he gives a brief overview of DNS calculations and where they stand at present. He next introduces the two most popular approaches for doing turbulent computations currently in use, namely, the Reynolds averaging of the N.-S. equations (RANS) and large-eddy simulation (LES). Approximations, often ad hoc ones, are present in these methods because use is made of heuristic models for turbulence quantities (the Reynolds stresses) which are otherwise unknown. They then introduce a new computational method called additive turbulent decomposition (ATD), the small-scale version of which is the topic of this research. The rest of the thesis is organized as follows. In Chapter 2 he describes the ATD procedure in greater detail; how dependent variables are split and the decomposition into large- and small-scale sets of equations. In Chapter 3 the spectral projection of the small-scale momentum equations are derived in detail. In Chapter 4 results of the computations with the small-scale ATD equations are presented. In Chapter 5 he describes the data-fitting procedure which can be used to directly specify the parameters of a chaotic-map turbulence model.

  1. Linking process, structure, property, and performance for metal-based additive manufacturing: computational approaches with experimental support

    NASA Astrophysics Data System (ADS)

    Smith, Jacob; Xiong, Wei; Yan, Wentao; Lin, Stephen; Cheng, Puikei; Kafka, Orion L.; Wagner, Gregory J.; Cao, Jian; Liu, Wing Kam

    2016-04-01

    Additive manufacturing (AM) methods for rapid prototyping of 3D materials (3D printing) have become increasingly popular with a particular recent emphasis on those methods used for metallic materials. These processes typically involve an accumulation of cyclic phase changes. The widespread interest in these methods is largely stimulated by their unique ability to create components of considerable complexity. However, modeling such processes is exceedingly difficult due to the highly localized and drastic material evolution that often occurs over the course of the manufacture time of each component. Final product characterization and validation are currently driven primarily by experimental means as a result of the lack of robust modeling procedures. In the present work, the authors discuss primary detrimental hurdles that have plagued effective modeling of AM methods for metallic materials while also providing logical speculation into preferable research directions for overcoming these hurdles. The primary focus of this work encompasses the specific areas of high-performance computing, multiscale modeling, materials characterization, process modeling, experimentation, and validation for final product performance of additively manufactured metallic components.

  2. Accuracy Maximization Analysis for Sensory-Perceptual Tasks: Computational Improvements, Filter Robustness, and Coding Advantages for Scaled Additive Noise

    PubMed Central

    Burge, Johannes

    2017-01-01

    Accuracy Maximization Analysis (AMA) is a recently developed Bayesian ideal observer method for task-specific dimensionality reduction. Given a training set of proximal stimuli (e.g. retinal images), a response noise model, and a cost function, AMA returns the filters (i.e. receptive fields) that extract the most useful stimulus features for estimating a user-specified latent variable from those stimuli. Here, we first contribute two technical advances that significantly reduce AMA’s compute time: we derive gradients of cost functions for which two popular estimators are appropriate, and we implement a stochastic gradient descent (AMA-SGD) routine for filter learning. Next, we show how the method can be used to simultaneously probe the impact on neural encoding of natural stimulus variability, the prior over the latent variable, noise power, and the choice of cost function. Then, we examine the geometry of AMA’s unique combination of properties that distinguish it from better-known statistical methods. Using binocular disparity estimation as a concrete test case, we develop insights that have general implications for understanding neural encoding and decoding in a broad class of fundamental sensory-perceptual tasks connected to the energy model. Specifically, we find that non-orthogonal (partially redundant) filters with scaled additive noise tend to outperform orthogonal filters with constant additive noise; non-orthogonal filters and scaled additive noise can interact to sculpt noise-induced stimulus encoding uncertainty to match task-irrelevant stimulus variability. Thus, we show that some properties of neural response thought to be biophysical nuisances can confer coding advantages to neural systems. Finally, we speculate that, if repurposed for the problem of neural systems identification, AMA may be able to overcome a fundamental limitation of standard subunit model estimation. As natural stimuli become more widely used in the study of psychophysical and

  3. Ab initio quasi-particle approximation bandgaps of silicon nanowires calculated at density functional theory/local density approximation computational effort

    SciTech Connect

    Ribeiro, M.

    2015-06-21

    Ab initio calculations of hydrogen-passivated Si nanowires were performed using density functional theory within LDA-1/2, to account for the excited states properties. A range of diameters was calculated to draw conclusions about the ability of the method to correctly describe the main trends of bandgap, quantum confinement, and self-energy corrections versus the diameter of the nanowire. Bandgaps are predicted with excellent accuracy if compared with other theoretical results like GW, and with the experiment as well, but with a low computational cost.

  4. Quadratic Programming for Allocating Control Effort

    NASA Technical Reports Server (NTRS)

    Singh, Gurkirpal

    2005-01-01

    A computer program calculates an optimal allocation of control effort in a system that includes redundant control actuators. The program implements an iterative (but otherwise single-stage) algorithm of the quadratic-programming type. In general, in the quadratic-programming problem, one seeks the values of a set of variables that minimize a quadratic cost function, subject to a set of linear equality and inequality constraints. In this program, the cost function combines control effort (typically quantified in terms of energy or fuel consumed) and control residuals (differences between commanded and sensed values of variables to be controlled). In comparison with prior control-allocation software, this program offers approximately equal accuracy but much greater computational efficiency. In addition, this program offers flexibility, robustness to actuation failures, and a capability for selective enforcement of control requirements. The computational efficiency of this program makes it suitable for such complex, real-time applications as controlling redundant aircraft actuators or redundant spacecraft thrusters. The program is written in the C language for execution in a UNIX operating system.

  5. The Effect of Emphasizing Mathematical Structure in the Acquisition of Whole Number Computation Skills (Addition and Subtraction) By Seven- and Eight-Year Olds: A Clinical Investigation.

    ERIC Educational Resources Information Center

    Uprichard, A. Edward; Collura, Carolyn

    This investigation sought to determine the effect of emphasizing mathematical structure in the acquisition of computational skills by seven- and eight-year-olds. The meaningful development-of-structure approach emphasized closure, commutativity, associativity, and the identity element of addition; the inverse relationship between addition and…

  6. NASA Efforts on Nanotechnology

    NASA Technical Reports Server (NTRS)

    Miranda, Felix A.

    2003-01-01

    An overview of the field of nanotechnology within the theme of "New efforts in Nanotechnology Research," will be presented. NASA's interest, requirements and current efforts in this emerging field will be discussed. In particular, NASA efforts to develop nanoelectronic devices, fuel cells, and other applications of interest using this novel technology by collaborating with academia will be addressed. Progress on current collaborations in this area with the University of Puerto Rico will be highlighted.

  7. Effort in Multitasking: Local and Global Assessment of Effort.

    PubMed

    Kiesel, Andrea; Dignath, David

    2017-01-01

    When performing multiple tasks in succession, self-organization of task order might be superior compared to external-controlled task schedules, because self-organization allows optimizing processing modes and thus reduces switch costs, and it increases commitment to task goals. However, self-organization is an additional executive control process that is not required if task order is externally specified and as such it is considered as time-consuming and effortful. To compare self-organized and externally controlled task scheduling, we suggest assessing global subjective and objectives measures of effort in addition to local performance measures. In our new experimental approach, we combined characteristics of dual tasking settings and task switching settings and compared local and global measures of effort in a condition with free choice of task sequence and a condition with cued task sequence. In a multi-tasking environment, participants chose the task order while the task requirement of the not-yet-performed task remained the same. This task preview allowed participants to work on the previously non-chosen items in parallel and resulted in faster responses and fewer errors in task switch trials than in task repetition trials. The free-choice group profited more from this task preview than the cued group when considering local performance measures. Nevertheless, the free-choice group invested more effort than the cued group when considering global measures. Thus, self-organization in task scheduling seems to be effortful even in conditions in which it is beneficiary for task processing. In a second experiment, we reduced the possibility of task preview for the not-yet-performed tasks in order to hinder efficient self-organization. Here neither local nor global measures revealed substantial differences between the free-choice and a cued task sequence condition. Based on the results of both experiments, we suggest that global assessment of effort in addition to

  8. Effort in Multitasking: Local and Global Assessment of Effort

    PubMed Central

    Kiesel, Andrea; Dignath, David

    2017-01-01

    When performing multiple tasks in succession, self-organization of task order might be superior compared to external-controlled task schedules, because self-organization allows optimizing processing modes and thus reduces switch costs, and it increases commitment to task goals. However, self-organization is an additional executive control process that is not required if task order is externally specified and as such it is considered as time-consuming and effortful. To compare self-organized and externally controlled task scheduling, we suggest assessing global subjective and objectives measures of effort in addition to local performance measures. In our new experimental approach, we combined characteristics of dual tasking settings and task switching settings and compared local and global measures of effort in a condition with free choice of task sequence and a condition with cued task sequence. In a multi-tasking environment, participants chose the task order while the task requirement of the not-yet-performed task remained the same. This task preview allowed participants to work on the previously non-chosen items in parallel and resulted in faster responses and fewer errors in task switch trials than in task repetition trials. The free-choice group profited more from this task preview than the cued group when considering local performance measures. Nevertheless, the free-choice group invested more effort than the cued group when considering global measures. Thus, self-organization in task scheduling seems to be effortful even in conditions in which it is beneficiary for task processing. In a second experiment, we reduced the possibility of task preview for the not-yet-performed tasks in order to hinder efficient self-organization. Here neither local nor global measures revealed substantial differences between the free-choice and a cued task sequence condition. Based on the results of both experiments, we suggest that global assessment of effort in addition to

  9. Quantum ring-polymer contraction method: Including nuclear quantum effects at no additional computational cost in comparison to ab initio molecular dynamics

    NASA Astrophysics Data System (ADS)

    John, Christopher; Spura, Thomas; Habershon, Scott; Kühne, Thomas D.

    2016-04-01

    We present a simple and accurate computational method which facilitates ab initio path-integral molecular dynamics simulations, where the quantum-mechanical nature of the nuclei is explicitly taken into account, at essentially no additional computational cost in comparison to the corresponding calculation using classical nuclei. The predictive power of the proposed quantum ring-polymer contraction method is demonstrated by computing various static and dynamic properties of liquid water at ambient conditions using density functional theory. This development will enable routine inclusion of nuclear quantum effects in ab initio molecular dynamics simulations of condensed-phase systems.

  10. Polylactides in additive biomanufacturing.

    PubMed

    Poh, Patrina S P; Chhaya, Mohit P; Wunner, Felix M; De-Juan-Pardo, Elena M; Schilling, Arndt F; Schantz, Jan-Thorsten; van Griensven, Martijn; Hutmacher, Dietmar W

    2016-12-15

    New advanced manufacturing technologies under the alias of additive biomanufacturing allow the design and fabrication of a range of products from pre-operative models, cutting guides and medical devices to scaffolds. The process of printing in 3 dimensions of cells, extracellular matrix (ECM) and biomaterials (bioinks, powders, etc.) to generate in vitro and/or in vivo tissue analogue structures has been termed bioprinting. To further advance in additive biomanufacturing, there are many aspects that we can learn from the wider additive manufacturing (AM) industry, which have progressed tremendously since its introduction into the manufacturing sector. First, this review gives an overview of additive manufacturing and both industry and academia efforts in addressing specific challenges in the AM technologies to drive toward AM-enabled industrial revolution. After which, considerations of poly(lactides) as a biomaterial in additive biomanufacturing are discussed. Challenges in wider additive biomanufacturing field are discussed in terms of (a) biomaterials; (b) computer-aided design, engineering and manufacturing; (c) AM and additive biomanufacturing printers hardware; and (d) system integration. Finally, the outlook for additive biomanufacturing was discussed.

  11. Computer Literacy...Would Plato Understand?

    ERIC Educational Resources Information Center

    Brown, Peggy, Ed.

    1983-01-01

    The uses of computers by colleges and universities are described, and some definitions of computer literacy are proposed. In addition, an essay, "Computing and Higher Education: The Revolution Is Through the Gates," by Robert G. Gillespie briefly considers the efforts colleges are making to explore the potential of the personal computer.…

  12. The effect of sleep loss on next day effort.

    PubMed

    Engle-Friedman, Mindy; Riela, Suzanne; Golan, Rama; Ventuneac, Ana M; Davis, Christine M; Jefferson, Angela D; Major, Donna

    2003-06-01

    The study had two primary objectives. The first was to determine whether sleep loss results in a preference for tasks demanding minimal effort. The second was to evaluate the quality of performance when participants, under conditions of sleep loss, have control over task demands. In experiment 1, using a repeated-measures design, 50 undergraduate college students were evaluated, following one night of no sleep loss and one night of sleep loss. The Math Effort Task (MET) presented addition problems via computer. Participants were able to select additions at one of five levels of difficulty. Less-demanding problems were selected and more additions were solved correctly when the participants were subject to sleep loss. In experiment 2, 58 undergraduate college students were randomly assigned to a no sleep deprivation or a sleep deprivation condition. Sleep-deprived participants selected less-demanding problems on the MET. Percentage correct on the MET was equivalent for both the non-sleep-deprived and sleep-deprived groups. On a task selection question, the sleep-deprived participants also selected significantly less-demanding non-academic tasks. Increased sleepiness, fatigue, and reaction time were associated with the selection of less difficult tasks. Both groups of participants reported equivalent effort expenditures; sleep-deprived participants did not perceive a reduction in effort. These studies demonstrate that sleep loss results in the choice of low-effort behavior that helps maintain accurate responding.

  13. Breckinridge Project, initial effort

    SciTech Connect

    1982-01-01

    Report V, Volume 4 provides descriptions, data, and drawings pertaining to Instrument and Plant Air Systems (Plant 36), Telecommunication Systems (Plant 37), Inert Gas Systems (Plant 38), Purge and Flush Oil Systems (Plant 39), Site Development and Roads (Plant 40), Buildings (Plant 41), Solid Waste Management (Plant 42), and Landfill (Plant 44). Instrument and Plant Air Systems (Plant 36) includes all equipment and piping necessary to supply instrument and utility air to the process plants and offsite facilities. Telecommunication Systems (Plant 37) includes the equipment and wiring for: communication throughout the facility; communication between plant data processing systems and offsite computing facilities; and communication with transportation carriers. Inert Gas Systems (Plant 38) provides high purity and low purity nitrogen streams for plant startup and normal operation. Purge and Flush Oil Systems (Plant 39) provides purge and flush oils to various plants. Site Development and Roads (Plant 40) provides site leveling, the addition of roads, fencing, and drainage, and the placement of fills, pilings, footings, and foundations for plants. Buildings (Plant 41) provides buildings for equipment and for personnel, including utilities, lighting, sanitary facilities, heating, air conditioning, and ventilation. Solid Waste Management (Plant 42) identifies, characterizes, segregates, and transports the various types of solid wastes to either Landfill (Plant 44) or outside disposal sites. Landfill (Plant 44) provides disposal of both nonhazardous and hazardous solid wastes. Information is included (as applicable) for each of the eight plants described.

  14. An Experimental and Computational Approach to Defining Structure/Reactivity Relationships for Intramolecular Addition Reactions to Bicyclic Epoxonium Ions

    PubMed Central

    Wan, Shuangyi; Gunaydin, Hakan; Houk, K. N.; Floreancig, Paul E.

    2008-01-01

    In this manuscript we report that oxidative cleavage reactions can be used to form oxocarbenium ions that react with pendent epoxides to form bicyclic epoxonium ions as an entry to the formation of cyclic oligoether compounds. Bicyclic epoxonium ion structure was shown to have a dramatic impact on the ratio of exo- to endo-cyclization reactions, with bicyclo[4.1.0] intermediates showing a strong preference for endo-closures and bicyclo[3.1.0] intermediates showing a preference for exo-closures. Computational studies on the structures and energetics of the transition states using the B3LYP/6-31G(d) method provide substantial insight into the origins of this selectivity. PMID:17547399

  15. The Ideal Promotion Effort.

    ERIC Educational Resources Information Center

    Morris, Edward L.

    The ideal promotional effort for an educational television (ETV) station is dependent on a professional approach to the problem. This means that each ETV station should employ a public relations manager and should keep him informed about all major station decisions. The Public Broadcasting Service (PBS) has a campaign of its own to bring attention…

  16. Assessing Public Relations Efforts

    ERIC Educational Resources Information Center

    Slocum, Doris; Johnson, T. Earle, Jr.

    1977-01-01

    The need to establish goals and objectives for public relations activities is discussed, followed by descriptions of several evaluation techniques for public relations programs. The continuous education of faculty regarding costs and logistics of publicity, and long-term continuity in the public relations effort are stressed as essential elements…

  17. Computer Model of Biopolymer Crystal Growth and Aggregation by Addition of Macromolecular Units — a Comparative Study

    NASA Astrophysics Data System (ADS)

    Siódmiak, J.; Gadomski, A.

    We discuss the results of a computer simulation of the biopolymer crystal growth and aggregation based on the 2D lattice Monte Carlo technique and the HP approximation of the biopolymers. As a modeled molecule (growth unit) we comparatively consider the previously studied non-mutant lysozyme protein, Protein Data Bank (PDB) ID: 193L, which forms, under a certain set of thermodynamic-kinetic conditions, the tetragonal crystals, and an amyloidogenic variant of the lysozyme, PDB ID: 1LYY, which is known as fibril-yielding and prone-to-aggregation agent. In our model, the site-dependent attachment, detachment and migration processes are involved. The probability of growth unit motion, attachment and detachment to/from the crystal surface are assumed to be proportional to the orientational factor representing the anisotropy of the molecule. Working within a two-dimensional representation of the truly three-dimensional process, we also argue that the crystal grows in a spiral way, whereby one or more screw dislocations on the crystal surface give rise to a terrace. We interpret the obtained results in terms of known models of crystal growth and aggregation such as B-C-F (Burton-Cabrera-Frank) dislocation driven growth and M-S (Mullins-Sekerka) instability concept, with stochastic aspects supplementing the latter. We discuss the conditions under which crystals vs non-crystalline protein aggregates appear, and how the process depends upon difference in chemical structure of the protein molecule seen as the main building block of the elementary crystal cell.

  18. Effects of protonation and C5 methylation on the electrophilic addition reaction of cytosine: a computational study.

    PubMed

    Jin, Lingxia; Wang, Wenliang; Hu, Daodao; Min, Suotian

    2013-01-10

    The mechanism for the effects of protonation and C5 methylation on the electrophilic addition reaction of Cyt has been explored by means of CBS-QB3 and CBS-QB3/PCM methods. In the gas phase, three paths, two protonated paths (N3 and O2 protonated paths B and C) as well as one neutral path (path A), were mainly discussed, and the calculated results indicate that the reaction of the HSO(3)(-) group with neutral Cyt is unlikely because of its high activation free energy, whereas O2-protonated path (path C) is the most likely to occur. In the aqueous phase, path B is the most feasible mechanism to account for the fact that the activation free energy of path B decreases compared with the corresponding path in the gas phase, whereas those of paths A and C increase. The main striking results are that the HSO(3)(-) group directly interacts with the C5═C6 bond rather than the N3═C4 bond and that the C5 methylation, compared with Cyt, by decreasing values of global electrophilicity index manifests that C5 methylation forms are less electrophilic power as well as by decreasing values of NPA charges on C5 site of the intermediates make the trend of addition reaction weaken, which is in agreement with the experimental observation that the rate of 5-MeCyt reaction is approximately 2 orders of magnitude slower than that of Cyt in the presence of bisulfite. Apart from cis and trans isomers, the rare third isomer where both the CH(3) and SO(3) occupy axial positions has been first found in the reactions of neutral and protonated 5-MeCyt with the HSO(3)(-) group. Furthermore, the transformation of the third isomer from the cis isomer can occur easily.

  19. 48 CFR 27.406-2 - Additional data requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... effort will in the future exceed $500,000, even though the initial award does not, the contracting... (d)). (c) Absent an established program for dissemination of computer software, agencies should not order additional computer software under the clause at 52.227-16, for the sole purpose of...

  20. Telecommunications: Additional Federal Efforts Could Help Advance Digital Television Transition

    NASA Astrophysics Data System (ADS)

    2002-11-01

    The transition to broadcast digital television(DTV) will provide new television services and the improved picture quality of 'high definition television'. It will also allow some portions of the radiofrequency spectrum used for broadcasting to be returned for public safety and commercial uses. The Congress set December 2006 as the target date for completing the DTV transition and turning the analog broadcast signals. However, this date can be extended if fewer than 85 percent of households in a market are able to receive the digital signals. GAO (General Accounting Office) was asked to assess issues related to the DTV transition.

  1. Do people with schizophrenia have difficulty anticipating pleasure, engaging in effortful behavior, or both?

    PubMed

    Gard, David E; Sanchez, Amy H; Cooper, Kathryn; Fisher, Melissa; Garrett, Coleman; Vinogradov, Sophia

    2014-11-01

    Motivation deficits are common in schizophrenia, but little is known about underlying mechanisms, or the specific goals that people with schizophrenia set in daily life. Using neurobiological heuristics of pleasure anticipation and effort assessment, we examined the quality of activities and goals of 47 people with and 41 people without schizophrenia, utilizing ecological momentary assessment. Participants were provided cell phones and called 4 times a day for 7 days, and were asked about their current activities and anticipation of upcoming goals. Activities and goals were later coded by independent raters on pleasure and effort. In line with recent laboratory findings on effort computation deficits in schizophrenia, relative to healthy participants, people with schizophrenia reported engaging in less effortful activities and setting less effortful goals, which were related to patient functioning. In addition, patients showed some inaccuracy in estimating how difficult an effortful goal would be, which in turn was associated with lower neurocognition. In contrast to previous research, people with schizophrenia engaged in activities and set goals that were more pleasure-based, and anticipated goals as being more pleasurable than controls. Thus, this study provided evidence for difficulty with effortful behavior and not anticipation of pleasure. These findings may have psychosocial treatment implications, focusing on effort assessment or effort expenditure. For example, to help people with schizophrenia engage in more meaningful goal pursuits, treatment providers may leverage low-effort pleasurable goals by helping patients to break down larger, more complex goals into smaller, lower-effort steps that are associated with specific pleasurable rewards.

  2. UV RESEARCH - FUNDED AND IN HOUSE EFFORTS

    EPA Science Inventory

    The National Risk Management research Laboratory (NRMRL) has performed or funded limited in-house and extramural research on the disinfection of CCL listed organisms using ultraviolet (UV) irradiation. In addition, multiple extramural efforts have been funded to assess operation...

  3. Navy superconductivity efforts

    NASA Technical Reports Server (NTRS)

    Gubser, D. U.

    1990-01-01

    Both the new high temperature superconductors (HTS) and the low temperature superconductors (LTS) are important components of Navy's total plan to integrate superconductivity into field operational systems. Fundamental research is an important component of the total Navy program and focuses on the HTS materials. Power applications (ship propulsion, etc.) use LTS materials while space applications (MMW electronics, etc.) use HTS materials. The Space Experiment being conducted at NRL will involve space flight testing of HTS devices built by industry and will demonstrate the ability to engineer and space qualify these devices for systems use. Another important component of the Navy's effort is the development of Superconducting Quantum Interference Device (SQUID) magnetometers. This program will use LTS materials initially, but plans to implement HTS materials as soon as possible. Hybrid HTS/LTS systems are probable in many applications. A review of the status of the Navy's HTS materials research is given as well as an update on the Navy's development efforts in superconductivity, with particular emphasis on the related SDIO sponsored program on HTS applications.

  4. Navy superconductivity efforts

    NASA Astrophysics Data System (ADS)

    Gubser, D. U.

    1990-04-01

    Both the new high temperature superconductors (HTS) and the low temperature superconductors (LTS) are important components of Navy's total plan to integrate superconductivity into field operational systems. Fundamental research is an important component of the total Navy program and focuses on the HTS materials. Power applications (ship propulsion, etc.) use LTS materials while space applications (MMW electronics, etc.) use HTS materials. The Space Experiment being conducted at NRL will involve space flight testing of HTS devices built by industry and will demonstrate the ability to engineer and space qualify these devices for systems use. Another important component of the Navy's effort is the development of Superconducting Quantum Interference Device (SQUID) magnetometers. This program will use LTS materials initially, but plans to implement HTS materials as soon as possible. Hybrid HTS/LTS systems are probable in many applications. A review of the status of the Navy's HTS materials research is given as well as an update on the Navy's development efforts in superconductivity, with particular emphasis on the related SDIO sponsored program on HTS applications.

  5. Cassini launch contingency effort

    NASA Astrophysics Data System (ADS)

    Chang, Yale; O'Neil, John M.; McGrath, Brian E.; Heyler, Gene A.; Brenza, Pete T.

    2002-01-01

    On 15 October 1997 at 4:43 AM EDT, the Cassini spacecraft was successfully launched on a Titan IVB/Centaur on a mission to explore the Saturnian system. It carried three Radioisotope Thermoelectric Generators (RTGs) and 117 Light Weight Radioisotope Heater Units (LWRHUs). As part of the joint National Aeronautics and Space Administration (NASA)/U.S. Department of Energy (DoE) safety effort, a contingency plan was prepared to address the unlikely events of an accidental suborbital reentry or out-of-orbital reentry. The objective of the plan was to develop procedures to predict, within hours, the Earth impact footprints (EIFs) for the nuclear heat sources released during the atmospheric reentry. The footprint predictions would be used in subsequent notification and recovery efforts. As part of a multi-agency team, The Johns Hopkins University Applied Physics Laboratory (JHU/APL) had the responsibility to predict the EIFs of the heat sources after a reentry, given the heat sources' release conditions from the main spacecraft. (No ablation burn-through of the heat sources' aeroshells was expected, as a result of earlier testing.) JHU/APL's other role was to predict the time of reentry from a potential orbital decay. The tools used were a three degree-of-freedom trajectory code, a database of aerodynamic coefficients for the heat sources, secure links to obtain tracking data, and a high fidelity special perturbation orbit integrator code to predict time of spacecraft reentry from orbital decay. In the weeks and days prior to launch, all the codes and procedures were exercised. Notional EIFs were derived from hypothetical reentry conditions. EIFs predicted by JHU/APL were compared to those by JPL and US SPACECOM, and were found to be in good agreement. The reentry time from orbital decay for a booster rocket for the Russian Progress M-36 freighter, a cargo ship for the Mir space station, was predicted to within 5 minutes more than two hours before reentry. For the

  6. Breckinridge Project, initial effort

    SciTech Connect

    None, None

    1982-09-01

    Report III, Volume 1 contains those specifications numbered A through J, as follows: General Specifications (A); Specifications for Pressure Vessels (C); Specifications for Tanks (D); Specifications for Exchangers (E); Specifications for Fired Heaters (F); Specifications for Pumps and Drivers (G); and Specifications for Instrumentation (J). The standard specifications of Bechtel Petroleum Incorporated have been amended as necessary to reflect the specific requirements of the Breckinridge Project, and the more stringent specifications of Ashland Synthetic Fuels, Inc. These standard specifications are available to the Initial Effort (Phase Zero) work performed by all contractors and subcontractors. Report III, Volume 1 also contains the unique specifications prepared for Plants 8, 15, and 27. These specifications will be substantially reviewed during Phase I of the project, and modified as necessary for use during the engineering, procurement, and construction of this project.

  7. Computational Model Builder for Multi-Dimensional Models

    DTIC Science & Technology

    2015-08-12

    In addition tools to support both the Environmental Simulation Effort (ES) and the Engineered Resilient Systems (ERS). Various ParaView extensions...support ERDC’s Environmental Simulation (ES) effort as well as ERDC’s Engineered Resilient Systems (ERS) effort. Computational Model Builder Suite...Distribution Statement A: Approved for public release; distribution unlimited. UNCLASSIFIED Engineered Resilient Systems (ERS) Support

  8. Worldwide effort against smoking.

    PubMed

    1986-07-01

    The 39th World Health Assembly, which met in May 1986, recognized the escalating health problem of smoking-related diseases and affirmed that tobacco smoking and its use in other forms are incompatible with the attainment of "Health for All by the Year 2000." If properly implemented, antismoking campaigns can decrease the prevalence of smoking. Nations as a whole must work toward changing smoking habits, and governments must support these efforts by officially stating their stand against smoking. Over 60 countries have introduced legislation affecting smoking. The variety of policies range from adopting a health education program designed to increase peoples' awareness of its dangers to increasing taxes to deter smoking by increasing tobacco prices. Each country must adopt an antismoking campaign which works most effectively within the cultural parameters of the society. Other smoking policies include: printed warnings on cigarette packages; health messages via radio, television, mobile teams, pamphlets, health workers, clinic walls, and newspapers; prohibition of smoking in public areas and transportation; prohibition of all advertisement of cigarettes and tobacco; and the establishment of upper limits of tar and nicotine content in cigarettes. The tobacco industry spends about $2000 million annually on worldwide advertising. According to the World Health Organization (WHO), controlling this overabundance of tobacco advertisements is a major priority in preventing the spread of smoking. Cigarette and tobacco advertising can be controlled to varying degrees, e.g., over a dozen countries have enacted a total ban on advertising on television or radio, a mandatory health warning must accompany advertisements in other countries, and tobacco companies often are prohibited from sponsoring sports events. Imposing a substantial tax on cigarettes is one of the most effective means to deter smoking. However, raising taxes and banning advertisements is not enough because

  9. Swedish nuclear waste efforts

    SciTech Connect

    Rydberg, J.

    1981-09-01

    After the introduction of a law prohibiting the start-up of any new nuclear power plant until the utility had shown that the waste produced by the plant could be taken care of in an absolutely safe way, the Swedish nuclear utilities in December 1976 embarked on the Nuclear Fuel Safety Project, which in November 1977 presented a first report, Handling of Spent Nuclear Fuel and Final Storage of Vitrified Waste (KBS-I), and in November 1978 a second report, Handling and Final Storage of Unreprocessed Spent Nuclear Fuel (KBS II). These summary reports were supported by 120 technical reports prepared by 450 experts. The project engaged 70 private and governmental institutions at a total cost of US $15 million. The KBS-I and KBS-II reports are summarized in this document, as are also continued waste research efforts carried out by KBS, SKBF, PRAV, ASEA and other Swedish organizations. The KBS reports describe all steps (except reprocessing) in handling chain from removal from a reactor of spent fuel elements until their radioactive waste products are finally disposed of, in canisters, in an underground granite depository. The KBS concept relies on engineered multibarrier systems in combination with final storage in thoroughly investigated stable geologic formations. This report also briefly describes other activities carried out by the nuclear industry, namely, the construction of a central storage facility for spent fuel elements (to be in operation by 1985), a repository for reactor waste (to be in operation by 1988), and an intermediate storage facility for vitrified high-level waste (to be in operation by 1990). The R and D activities are updated to September 1981.

  10. Disrupting the supplementary motor area makes physical effort appear less effortful.

    PubMed

    Zénon, Alexandre; Sidibé, Mariam; Olivier, Etienne

    2015-06-10

    The perception of physical effort is relatively unaffected by the suppression of sensory afferences, indicating that this function relies mostly on the processing of the central motor command. Neural signals in the supplementary motor area (SMA) correlate with the intensity of effort, suggesting that the motor signal involved in effort perception could originate from this area, but experimental evidence supporting this view is still lacking. Here, we tested this hypothesis by disrupting neural activity in SMA, in primary motor cortex (M1), or in a control site by means of continuous theta-burst transcranial magnetic stimulation, while measuring effort perception during grip forces of different intensities. After each grip force exertion, participants had the opportunity to either accept or refuse to replicate the same effort for varying amounts of reward. In addition to the subjective rating of perceived exertion, effort perception was estimated on the basis of the acceptance rate, the effort replication accuracy, the influence of the effort exerted in trial t on trial t+1, and pupil dilation. We found that disruption of SMA activity, but not of M1, led to a consistent decrease in effort perception, whatever the measure used to assess it. Accordingly, we modeled effort perception in a structural equation model and found that only SMA disruption led to a significant alteration of effort perception. These findings indicate that effort perception relies on the processing of a signal originating from motor-related neural circuits upstream of M1 and that SMA is a key node of this network.

  11. Is Effort Praise Motivational? The Role of Beliefs in the Effort-Ability Relationship

    ERIC Educational Resources Information Center

    Lam, Shui-fong; Yim, Pui-shan; Ng, Yee-lam

    2008-01-01

    In two studies, we investigated how beliefs in the effort-ability relationship moderated the effects of effort praise on student motivation. Study 1 showed that the more the participants believed that effort and ability were related positively (the positive rule) versus related negatively (the inverse rule), the more they would have positive…

  12. Dataset of calcified plaque condition in the stenotic coronary artery lesion obtained using multidetector computed tomography to indicate the addition of rotational atherectomy during percutaneous coronary intervention.

    PubMed

    Akutsu, Yasushi; Hamazaki, Yuji; Sekimoto, Teruo; Kaneko, Kyouichi; Kodama, Yusuke; Li, Hui-Ling; Suyama, Jumpei; Gokan, Takehiko; Sakai, Koshiro; Kosaki, Ryota; Yokota, Hiroyuki; Tsujita, Hiroaki; Tsukamoto, Shigeto; Sakurai, Masayuki; Sambe, Takehiko; Oguchi, Katsuji; Uchida, Naoki; Kobayashi, Shinichi; Aoki, Atsushi; Kobayashi, Youichi

    2016-06-01

    Our data shows the regional coronary artery calcium scores (lesion CAC) on multidetector computed tomography (MDCT) and the cross-section imaging on MDCT angiography (CTA) in the target lesion of the patients with stable angina pectoris who were scheduled for percutaneous coronary intervention (PCI). CAC and CTA data were measured using a 128-slice scanner (Somatom Definition AS+; Siemens Medical Solutions, Forchheim, Germany) before PCI. CAC was measured in a non-contrast-enhanced scan and was quantified using the Calcium Score module of SYNAPSE VINCENT software (Fujifilm Co. Tokyo, Japan) and expressed in Agatston units. CTA were then continued with a contrast-enhanced ECG gating to measure the severity of the calcified plaque condition. We present that both CAC and CTA data are used as a benchmark to consider the addition of rotational atherectomy during PCI to severely calcified plaque lesions.

  13. Dataset of calcified plaque condition in the stenotic coronary artery lesion obtained using multidetector computed tomography to indicate the addition of rotational atherectomy during percutaneous coronary intervention

    PubMed Central

    Akutsu, Yasushi; Hamazaki, Yuji; Sekimoto, Teruo; Kaneko, Kyouichi; Kodama, Yusuke; Li, Hui-Ling; Suyama, Jumpei; Gokan, Takehiko; Sakai, Koshiro; Kosaki, Ryota; Yokota, Hiroyuki; Tsujita, Hiroaki; Tsukamoto, Shigeto; Sakurai, Masayuki; Sambe, Takehiko; Oguchi, Katsuji; Uchida, Naoki; Kobayashi, Shinichi; Aoki, Atsushi; Kobayashi, Youichi

    2016-01-01

    Our data shows the regional coronary artery calcium scores (lesion CAC) on multidetector computed tomography (MDCT) and the cross-section imaging on MDCT angiography (CTA) in the target lesion of the patients with stable angina pectoris who were scheduled for percutaneous coronary intervention (PCI). CAC and CTA data were measured using a 128-slice scanner (Somatom Definition AS+; Siemens Medical Solutions, Forchheim, Germany) before PCI. CAC was measured in a non-contrast-enhanced scan and was quantified using the Calcium Score module of SYNAPSE VINCENT software (Fujifilm Co. Tokyo, Japan) and expressed in Agatston units. CTA were then continued with a contrast-enhanced ECG gating to measure the severity of the calcified plaque condition. We present that both CAC and CTA data are used as a benchmark to consider the addition of rotational atherectomy during PCI to severely calcified plaque lesions. PMID:26977441

  14. Synthesis of Bridged Heterocycles via Sequential 1,4- and 1,2-Addition Reactions to α,β-Unsaturated N-Acyliminium Ions: Mechanistic and Computational Studies.

    PubMed

    Yazici, Arife; Wille, Uta; Pyne, Stephen G

    2016-02-19

    Novel tricyclic bridged heterocyclic systems can be readily prepared from sequential 1,4- and 1,2-addition reactions of allyl and 3-substituted allylsilanes to indolizidine and quinolizidine α,β-unsaturated N-acyliminium ions. These reactions involve a novel N-assisted, transannular 1,5-hydride shift. Such a mechanism was supported by examining the reaction of a dideuterated indolizidine, α,β-unsaturated N-acyliminium ion precursor, which provided specifically dideuterated tricyclic bridged heterocyclic products, and from computational studies. In contrast, the corresponding pyrrolo[1,2-a]azepine system did not provide the corresponding tricyclic bridged heterocyclic product and gave only a bis-allyl adduct, while more substituted versions gave novel furo[3,2-d]pyrrolo[1,2-a]azepine products. Such heterocyclic systems would be expected to be useful scaffolds for the preparation of libraries of novel compounds for new drug discovery programs.

  15. Breckinridge Project, initial effort

    SciTech Connect

    1982-01-01

    The project cogeneration plant supplies electric power, process steam and treated boiler feedwater for use by the project plants. The plant consists of multiple turbine generators and steam generators connected to a common main steam header. The major plant systems which are required to produce steam, electrical power and treated feedwater are discussed individually. The systems are: steam, steam generator, steam generator fuel, condensate and feedwater deaeration, condensate and blowdown collection, cooling water, boiler feedwater treatment, coal handling, ash handling (fly ash and bottom ash), electrical, and control system. The plant description is based on the Phase Zero design basis established for Plant 31 in July of 1980 and the steam/condensate balance as presented on Drawing 31-E-B-1. Updating of steam requirements as more refined process information becomes available has generated some changes in the steam balance. Boiler operation with these updated requirements is reflected on Drawing 31-D-B-1A. The major impact of updating has been that less 600 psig steam generated within the process units requires more extraction steam from the turbine generators to close the 600 psig steam balance. Since the 900 psig steam generation from the boilers was fixed at 1,200,000 lb/hr, the additional extraction steam required to close the 600 psig steam balance decreased the quantity of electrical power available from the turbine generators. In the next phase of engineering work, the production of 600 psig steam will be augmented by increasing convection bank steam generation in the Plant 3 fired heaters by 140,000 to 150,000 lb/hr. This modification will allow full rated power generation from the turbine generators.

  16. Respiratory effort from the photoplethysmogram.

    PubMed

    Addison, Paul S

    2017-03-01

    The potential for a simple, non-invasive measure of respiratory effort based on the pulse oximeter signal - the photoplethysmogram or 'pleth' - was investigated in a pilot study. Several parameters were developed based on a variety of manifestations of respiratory effort in the signal, including modulation changes in amplitude, baseline, frequency and pulse transit times, as well as distinct baseline signal shifts. Thirteen candidate parameters were investigated using data from healthy volunteers. Each volunteer underwent a series of controlled respiratory effort maneuvers at various set flow resistances and respiratory rates. Six oximeter probes were tested at various body sites. In all, over three thousand pleth-based effort-airway pressure (EP) curves were generated across the various airway constrictions, respiratory efforts, respiratory rates, subjects, probe sites, and the candidate parameters considered. Regression analysis was performed to determine the existence of positive monotonic relationships between the respiratory effort parameters and resulting airway pressures. Six of the candidate parameters investigated exhibited a distinct positive relationship (p<0.001 across all probes tested) with increasing upper airway pressure repeatable across the range of respiratory rates and flow constrictions studied. These were: the three fundamental modulations in amplitude (AM-Effort), baseline (BM-Effort) and respiratory sinus arrhythmia (RSA-Effort); two pulse transit time modulations - one using a pulse oximeter probe and an ECG (P2E-Effort) and the other using two pulse oximeter probes placed at different peripheral body sites (P2-Effort); and baseline shifts in heart rate, (BL-HR-Effort). In conclusion, a clear monotonic relationship was found between several pleth-based parameters and imposed respiratory loadings at the mouth across a range of respiratory rates and flow constrictions. The results suggest that the pleth may provide a measure of changing upper

  17. A computational study of the addition of ReO3L (L = Cl(-), CH3, OCH3 and Cp) to ethenone.

    PubMed

    Aniagyei, Albert; Tia, Richard; Adei, Evans

    2016-01-01

    The periselectivity and chemoselectivity of the addition of transition metal oxides of the type ReO3L (L = Cl, CH3, OCH3 and Cp) to ethenone have been explored at the MO6 and B3LYP/LACVP* levels of theory. The activation barriers and reaction energies for the stepwise and concerted addition pathways involving multiple spin states have been computed. In the reaction of ReO3L (L = Cl(-), OCH3, CH3 and Cp) with ethenone, the concerted [2 + 2] addition of the metal oxide across the C=C and C=O double bond to form either metalla-2-oxetane-3-one or metalla-2,4-dioxolane is the most kinetically favored over the formation of metalla-2,5-dioxolane-3-one from the direct [3 + 2] addition pathway. The trends in activation and reaction energies for the formation of metalla-2-oxetane-3-one and metalla-2,4-dioxolane are Cp < Cl(-) < OCH3 < CH3 and Cp < OCH3 < CH3 < Cl(-) and for the reaction energies are Cp < OCH3 < Cl(-) < CH3 and Cp < CH3 < OCH3 < Cl CH3. The concerted [3 + 2] addition of the metal oxide across the C=C double of the ethenone to form species metalla-2,5-dioxolane-3-one is thermodynamically the most favored for the ligand L = Cp. The direct [2 + 2] addition pathways leading to the formations of metalla-2-oxetane-3-one and metalla-2,4-dioxolane is thermodynamically the most favored for the ligands L = OCH3 and Cl(-). The difference between the calculated [2 + 2] activation barriers for the addition of the metal oxide LReO3 across the C=C and C=O functionalities of ethenone are small except for the case of L = Cl(-) and OCH3. The rearrangement of the metalla-2-oxetane-3-one-metalla-2,5-dioxolane-3-one even though feasible, are unfavorable due to high activation energies of their rate-determining steps. For the rearrangement of the metalla-2-oxetane-3-one to metalla-2,5-dioxolane-3-one, the trends in activation barriers is found to follow the order OCH3 < Cl(-) < CH3 < Cp. The trends in the activation energies for

  18. The special effort processing of FGGE data

    NASA Technical Reports Server (NTRS)

    1983-01-01

    The basic FGGE level IIb data set was enhanced. It focused on removing deficiencies in the objective methods of quality assurance, removing efficiencies in certain types of operationally produced satellite soundings, and removing deficiencies in certain types of operationally produced cloud tracked winds. The Special Effort was a joint NASA-NOAA-University of Wisconsin effort. The University of Wisconsin installed an interactive McIDAS capability on the Amdahl computer at the Goddard Laboratory of Atmospheric Sciences (GLAS) with one interactive video terminal at Goddard and the other at the World Weather Building. With this interactive capability a joint processing effort was undertaken to reprocess certain FGGE data sets. NOAA produced a specially edited data set for the special observing periods (SOPs) of FGGE. NASA produced an enhanced satellite sounding data set for the SOPs while the University of Wisconsin produced an enhanced cloud tracked wind set from the Japanese geostationary satellite images.

  19. Determination of Zinc-Based Additives in Lubricating Oils by Flow-Injection Analysis with Flame-AAS Detection Exploiting Injection with a Computer-Controlled Syringe.

    PubMed

    Pignalosa, Gustavo; Knochen, Moisés; Cabrera, Noel

    2005-01-01

    A flow-injection system is proposed for the determination of metal-based additives in lubricating oils. The system, operating under computer control uses a motorised syringe for measuring and injecting the oil sample (200 muL) in a kerosene stream, where it is dispersed by means of a packed mixing reactor and carried to an atomic absorption spectrometer which is used as detector. Zinc was used as model analyte. Two different systems were evaluated, one for low concentrations (range 0-10 ppm) and the second capable of providing higher dilution rates for high concentrations (range 0.02%-0.2% w/w). The sampling frequency was about 30 samples/h. Calibration curves fitted a second-degree regression model (r(2) = 0.996). Commercial samples with high and low zinc levels were analysed by the proposed method and the results were compared with those obtained with the standard ASTM method. The t test for mean values showed no significant differences at the 95% confidence level. Precision (RSD%) was better than 5% (2% typical) for the high concentrations system. The carryover between successive injections was found to be negligible.

  20. Determination of Zinc-Based Additives in Lubricating Oils by Flow-Injection Analysis with Flame-AAS Detection Exploiting Injection with a Computer-Controlled Syringe

    PubMed Central

    Pignalosa, Gustavo; Cabrera, Noel

    2005-01-01

    A flow-injection system is proposed for the determination of metal-based additives in lubricating oils. The system, operating under computer control uses a motorised syringe for measuring and injecting the oil sample (200 μL) in a kerosene stream, where it is dispersed by means of a packed mixing reactor and carried to an atomic absorption spectrometer which is used as detector. Zinc was used as model analyte. Two different systems were evaluated, one for low concentrations (range 0–10 ppm) and the second capable of providing higher dilution rates for high concentrations (range 0.02%–0.2% w/w). The sampling frequency was about 30 samples/h. Calibration curves fitted a second-degree regression model (r 2 = 0.996). Commercial samples with high and low zinc levels were analysed by the proposed method and the results were compared with those obtained with the standard ASTM method. The t test for mean values showed no significant differences at the 95% confidence level. Precision (RSD%) was better than 5% (2% typical) for the high concentrations system. The carryover between successive injections was found to be negligible. PMID:18924720

  1. Standardization efforts in IP telephony

    NASA Astrophysics Data System (ADS)

    Sengodan, Senthil; Bansal, Raj

    1999-11-01

    The recent interest in IP telephony has led to a tremendous increase of standardization activities in the area. The three main standards bodies in the area of IP telephony are the International Telecommunication Union's (ITU-T) Study Group (SG) 16, the Internet Engineering Task Force (IETF) and the European Telecommunication Standards Institute's (ETSI) TIPHON project. In addition, forums such as the International Multimedia Teleconferencing Consortium (IMTC), the Intelligent Network Forum (INF), the International Softswitch Consortium (ISC), the Electronic Computer Telephony Forum (ECTF), and the MIT's Internet Telephony Consortium (ITC) are looking into various other aspects that aim at the growth of this industry. This paper describes the main tasks (completed and in progress) undertaken by these organizations. In describing such work, an overview of the underlying technology is also provided.

  2. Supercomputer and cluster performance modeling and analysis efforts:2004-2006.

    SciTech Connect

    Sturtevant, Judith E.; Ganti, Anand; Meyer, Harold Edward; Stevenson, Joel O.; Benner, Robert E., Jr.; Goudy, Susan Phelps; Doerfler, Douglas W.; Domino, Stefan Paul; Taylor, Mark A.; Malins, Robert Joseph; Scott, Ryan T.; Barnette, Daniel Wayne; Rajan, Mahesh; Ang, James Alfred; Black, Amalia Rebecca; Laub, Thomas William; Vaughan, Courtenay Thomas; Franke, Brian Claude

    2007-02-01

    This report describes efforts by the Performance Modeling and Analysis Team to investigate performance characteristics of Sandia's engineering and scientific applications on the ASC capability and advanced architecture supercomputers, and Sandia's capacity Linux clusters. Efforts to model various aspects of these computers are also discussed. The goals of these efforts are to quantify and compare Sandia's supercomputer and cluster performance characteristics; to reveal strengths and weaknesses in such systems; and to predict performance characteristics of, and provide guidelines for, future acquisitions and follow-on systems. Described herein are the results obtained from running benchmarks and applications to extract performance characteristics and comparisons, as well as modeling efforts, obtained during the time period 2004-2006. The format of the report, with hypertext links to numerous additional documents, purposefully minimizes the document size needed to disseminate the extensive results from our research.

  3. Cognitive effort: A neuroeconomic approach

    PubMed Central

    Braver, Todd S.

    2015-01-01

    Cognitive effort has been implicated in numerous theories regarding normal and aberrant behavior and the physiological response to engagement with demanding tasks. Yet, despite broad interest, no unifying, operational definition of cognitive effort itself has been proposed. Here, we argue that the most intuitive and epistemologically valuable treatment is in terms of effort-based decision-making, and advocate a neuroeconomics-focused research strategy. We first outline psychological and neuroscientific theories of cognitive effort. Then we describe the benefits of a neuroeconomic research strategy, highlighting how it affords greater inferential traction than do traditional markers of cognitive effort, including self-reports and physiologic markers of autonomic arousal. Finally, we sketch a future series of studies that can leverage the full potential of the neuroeconomic approach toward understanding the cognitive and neural mechanisms that give rise to phenomenal, subjective cognitive effort. PMID:25673005

  4. Materials characterization on efforts for ablative materials

    NASA Technical Reports Server (NTRS)

    Tytula, Thomas P.; Schad, Kristin C.; Swann, Myles H.

    1992-01-01

    Experimental efforts to develop a new procedure to measure char depth in carbon phenolic nozzle material are described. Using a Shor Type D Durometer, hardness profiles were mapped across post fired sample blocks and specimens from a fired rocket nozzle. Linear regression was used to estimate the char depth. Results are compared to those obtained from computed tomography in a comparative experiment. There was no significant difference in the depth estimates obtained by the two methods.

  5. Additive Manufactured Product Integrity

    NASA Technical Reports Server (NTRS)

    Waller, Jess; Wells, Doug; James, Steve; Nichols, Charles

    2017-01-01

    NASA is providing key leadership in an international effort linking NASA and non-NASA resources to speed adoption of additive manufacturing (AM) to meet NASA's mission goals. Participants include industry, NASA's space partners, other government agencies, standards organizations and academia. Nondestructive Evaluation (NDE) is identified as a universal need for all aspects of additive manufacturing.

  6. Techniques of Assessing Mental Effort.

    ERIC Educational Resources Information Center

    Cennamo, Katherine S.

    The search for techniques to increase the effort that learners invest in video-based instruction has been hindered by the limitations of the instruments used to assess the construct of mental effort. Several researchers have noted the confusion of terms in the field that refer to the cognitive resources devoted to processing the stimulus. In this…

  7. Learning Environment and Student Effort

    ERIC Educational Resources Information Center

    Hopland, Arnt O.; Nyhus, Ole Henning

    2016-01-01

    Purpose: The purpose of this paper is to explore the relationship between satisfaction with learning environment and student effort, both in class and with homework assignments. Design/methodology/approach: The authors use data from a nationwide and compulsory survey to analyze the relationship between learning environment and student effort. The…

  8. Grading System and Student Effort

    ERIC Educational Resources Information Center

    Paredes, Valentina

    2017-01-01

    Several papers have proposed that the grading system affects students' incentives to exert effort. In particular, the previous literature has compared student effort under relative and absolute grading systems, but the results are mixed and the implications of the models have not been empirically tested. In this paper, I build a model where…

  9. EA Shuttle Document Retention Effort

    NASA Technical Reports Server (NTRS)

    Wagner, Howard A.

    2010-01-01

    This slide presentation reviews the effort of code EA at Johnson Space Center (JSC) to identify and acquire databases and documents from the space shuttle program that are adjudged important for retention after the retirement of the space shuttle.

  10. Computational crystallization.

    PubMed

    Altan, Irem; Charbonneau, Patrick; Snell, Edward H

    2016-07-15

    Crystallization is a key step in macromolecular structure determination by crystallography. While a robust theoretical treatment of the process is available, due to the complexity of the system, the experimental process is still largely one of trial and error. In this article, efforts in the field are discussed together with a theoretical underpinning using a solubility phase diagram. Prior knowledge has been used to develop tools that computationally predict the crystallization outcome and define mutational approaches that enhance the likelihood of crystallization. For the most part these tools are based on binary outcomes (crystal or no crystal), and the full information contained in an assembly of crystallization screening experiments is lost. The potential of this additional information is illustrated by examples where new biological knowledge can be obtained and where a target can be sub-categorized to predict which class of reagents provides the crystallization driving force. Computational analysis of crystallization requires complete and correctly formatted data. While massive crystallization screening efforts are under way, the data available from many of these studies are sparse. The potential for this data and the steps needed to realize this potential are discussed.

  11. Mapping Fishing Effort through AIS Data

    PubMed Central

    Natale, Fabrizio; Gibin, Maurizio; Alessandrini, Alfredo; Vespe, Michele; Paulrud, Anton

    2015-01-01

    Several research initiatives have been undertaken to map fishing effort at high spatial resolution using the Vessel Monitoring System (VMS). An alternative to the VMS is represented by the Automatic Identification System (AIS), which in the EU became compulsory in May 2014 for all fishing vessels of length above 15 meters. The aim of this paper is to assess the uptake of the AIS in the EU fishing fleet and the feasibility of producing a map of fishing effort with high spatial and temporal resolution at European scale. After analysing a large AIS dataset for the period January-August 2014 and covering most of the EU waters, we show that AIS was adopted by around 75% of EU fishing vessels above 15 meters of length. Using the Swedish fleet as a case study, we developed a method to identify fishing activity based on the analysis of individual vessels’ speed profiles and produce a high resolution map of fishing effort based on AIS data. The method was validated using detailed logbook data and proved to be sufficiently accurate and computationally efficient to identify fishing grounds and effort in the case of trawlers, which represent the largest portion of the EU fishing fleet above 15 meters of length. Issues still to be addressed before extending the exercise to the entire EU fleet are the assessment of coverage levels of the AIS data for all EU waters and the identification of fishing activity in the case of vessels other than trawlers. PMID:26098430

  12. Isothiourea-catalysed enantioselective pyrrolizine synthesis: synthetic and computational studies† †Electronic supplementary information (ESI) available: NMR spectra, HPLC analysis and computational co-ordinates. Data available.12 CCDC 1483759. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6ob01557c Click here for additional data file. Click here for additional data file. Click here for additional data file.

    PubMed Central

    Stark, Daniel G.; Williamson, Patrick; Gayner, Emma R.; Musolino, Stefania F.; Kerr, Ryan W. F.; Taylor, James E.; Slawin, Alexandra M. Z.; O'Riordan, Timothy J. C.

    2016-01-01

    The catalytic enantioselective synthesis of a range of cis-pyrrolizine carboxylate derivatives with outstanding stereocontrol (14 examples, >95 : 5 dr, >98 : 2 er) through an isothiourea-catalyzed intramolecular Michael addition-lactonisation and ring-opening approach from the corresponding enone acid is reported. An optimised and straightforward three-step synthetic route to the enone acid starting materials from readily available pyrrole-2-carboxaldehydes is delineated, with benzotetramisole (5 mol%) proving the optimal catalyst for the enantioselective process. Ring-opening of the pyrrolizine dihydropyranone products with either MeOH or a range of amines leads to the desired products in excellent yield and enantioselectivity. Computation has been used to probe the factors leading to high stereocontrol, with the formation of the observed cis-steroisomer predicted to be kinetically and thermodynamically favoured. PMID:27489030

  13. Dopamine, behavioral economics, and effort.

    PubMed

    Salamone, John D; Correa, Merce; Farrar, Andrew M; Nunes, Eric J; Pardo, Marta

    2009-01-01

    There are numerous problems with the hypothesis that brain dopamine (DA) systems, particularly in the nucleus accumbens, directly mediate the rewarding or primary motivational characteristics of natural stimuli such as food. Research and theory related to the functions of mesolimbic DA are undergoing a substantial conceptual restructuring, with the traditional emphasis on hedonia and primary reward yielding to other concepts and lines of inquiry. The present review is focused upon the involvement of nucleus accumbens DA in behavioral activation and effort-related processes. Viewed from the framework of behavioral economics, the effects of accumbens DA depletions and antagonism on food-reinforced behavior are highly dependent upon the work requirements of the instrumental task, and DA depleted rats are more sensitive to increases in response costs (i.e., ratio requirements). Moreover, interference with accumbens DA transmission exerts a powerful influence over effort-related choice behavior. Rats with accumbens DA depletions or antagonism reallocate their instrumental behavior away from food-reinforced tasks that have high response requirements, and instead these rats select a less-effortful type of food-seeking behavior. Nucleus accumbens DA and adenosine interact in the regulation of effort-related functions, and other brain structures (anterior cingulate cortex, amygdala, ventral pallidum) also are involved. Studies of the brain systems regulating effort-based processes may have implications for understanding drug abuse, as well as energy-related disorders such as psychomotor slowing, fatigue or anergia in depression and other neurological disorders.

  14. Dopamine, Behavioral Economics, and Effort

    PubMed Central

    Salamone, John D.; Correa, Merce; Farrar, Andrew M.; Nunes, Eric J.; Pardo, Marta

    2009-01-01

    There are numerous problems with the hypothesis that brain dopamine (DA) systems, particularly in the nucleus accumbens, directly mediate the rewarding or primary motivational characteristics of natural stimuli such as food. Research and theory related to the functions of mesolimbic DA are undergoing a substantial conceptual restructuring, with the traditional emphasis on hedonia and primary reward yielding to other concepts and lines of inquiry. The present review is focused upon the involvement of nucleus accumbens DA in behavioral activation and effort-related processes. Viewed from the framework of behavioral economics, the effects of accumbens DA depletions and antagonism on food-reinforced behavior are highly dependent upon the work requirements of the instrumental task, and DA depleted rats are more sensitive to increases in response costs (i.e., ratio requirements). Moreover, interference with accumbens DA transmission exerts a powerful influence over effort-related choice behavior. Rats with accumbens DA depletions or antagonism reallocate their instrumental behavior away from food-reinforced tasks that have high response requirements, and instead these rats select a less-effortful type of food-seeking behavior. Nucleus accumbens DA and adenosine interact in the regulation of effort-related functions, and other brain structures (anterior cingulate cortex, amygdala, ventral pallidum) also are involved. Studies of the brain systems regulating effort-based processes may have implications for understanding drug abuse, as well as energy-related disorders such as psychomotor slowing, fatigue or anergia in depression and other neurological disorders. PMID:19826615

  15. ASME Code Efforts Supporting HTGRs

    SciTech Connect

    D.K. Morton

    2012-09-01

    In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This report discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.

  16. ASME Code Efforts Supporting HTGRs

    SciTech Connect

    D.K. Morton

    2011-09-01

    In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This report discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.

  17. ASME Code Efforts Supporting HTGRs

    SciTech Connect

    D.K. Morton

    2010-09-01

    In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This report discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.

  18. Food additives

    PubMed Central

    Spencer, Michael

    1974-01-01

    Food additives are discussed from the food technology point of view. The reasons for their use are summarized: (1) to protect food from chemical and microbiological attack; (2) to even out seasonal supplies; (3) to improve their eating quality; (4) to improve their nutritional value. The various types of food additives are considered, e.g. colours, flavours, emulsifiers, bread and flour additives, preservatives, and nutritional additives. The paper concludes with consideration of those circumstances in which the use of additives is (a) justified and (b) unjustified. PMID:4467857

  19. GPU computing for systems biology.

    PubMed

    Dematté, Lorenzo; Prandi, Davide

    2010-05-01

    The development of detailed, coherent, models of complex biological systems is recognized as a key requirement for integrating the increasing amount of experimental data. In addition, in-silico simulation of bio-chemical models provides an easy way to test different experimental conditions, helping in the discovery of the dynamics that regulate biological systems. However, the computational power required by these simulations often exceeds that available on common desktop computers and thus expensive high performance computing solutions are required. An emerging alternative is represented by general-purpose scientific computing on graphics processing units (GPGPU), which offers the power of a small computer cluster at a cost of approximately $400. Computing with a GPU requires the development of specific algorithms, since the programming paradigm substantially differs from traditional CPU-based computing. In this paper, we review some recent efforts in exploiting the processing power of GPUs for the simulation of biological systems.

  20. Increasing Expectations for Student Effort.

    ERIC Educational Resources Information Center

    Schilling, Karen Maitland; Schilling, Karl L.

    1999-01-01

    States that few higher education institutions have publicly articulated clear expectations of the knowledge and skills students are to attain. Describes gap between student and faculty expectations for academic effort. Reports that what is required in students' first semester appears to play a strong role in shaping the time investments made in…

  1. Effort, success, and nonuse determine arm choice.

    PubMed

    Schweighofer, Nicolas; Xiao, Yupeng; Kim, Sujin; Yoshioka, Toshinori; Gordon, James; Osu, Rieko

    2015-07-01

    How do humans choose one arm or the other to reach single targets in front of the body? Current theories of reward-driven decisionmaking predict that choice results from a comparison of "action values," which are the expected rewards for possible actions in a given state. In addition, current theories of motor control predict that in planning arm movements, humans minimize an expected motor cost that balances motor effort and endpoint accuracy. Here, we test the hypotheses that arm choice is determined by comparison of action values comprising expected effort and expected task success for each arm, as well as a handedness bias. Right-handed subjects, in either a large or small target condition, were first instructed to use each hand in turn to shoot through an array of targets and then to choose either hand to shoot through the same targets. Effort was estimated via inverse kinematics and dynamics. A mixed-effects logistic-regression analysis showed that, as predicted, both expected effort and expected success predicted choice, as did arm use in the preceding trial. Finally, individual parameter estimation showed that the handedness bias correlated with mean difference between right- and left-arm success, leading to overall lower use of the left arm. We discuss our results in light of arm nonuse in individuals' poststroke.

  2. COMPUTATIONAL SCIENCE CENTER

    SciTech Connect

    DAVENPORT, J.

    2006-11-01

    Computational Science is an integral component of Brookhaven's multi science mission, and is a reflection of the increased role of computation across all of science. Brookhaven currently has major efforts in data storage and analysis for the Relativistic Heavy Ion Collider (RHIC) and the ATLAS detector at CERN, and in quantum chromodynamics. The Laboratory is host for the QCDOC machines (quantum chromodynamics on a chip), 10 teraflop/s computers which boast 12,288 processors each. There are two here, one for the Riken/BNL Research Center and the other supported by DOE for the US Lattice Gauge Community and other scientific users. A 100 teraflop/s supercomputer will be installed at Brookhaven in the coming year, managed jointly by Brookhaven and Stony Brook, and funded by a grant from New York State. This machine will be used for computational science across Brookhaven's entire research program, and also by researchers at Stony Brook and across New York State. With Stony Brook, Brookhaven has formed the New York Center for Computational Science (NYCCS) as a focal point for interdisciplinary computational science, which is closely linked to Brookhaven's Computational Science Center (CSC). The CSC has established a strong program in computational science, with an emphasis on nanoscale electronic structure and molecular dynamics, accelerator design, computational fluid dynamics, medical imaging, parallel computing and numerical algorithms. We have been an active participant in DOES SciDAC program (Scientific Discovery through Advanced Computing). We are also planning a major expansion in computational biology in keeping with Laboratory initiatives. Additional laboratory initiatives with a dependence on a high level of computation include the development of hydrodynamics models for the interpretation of RHIC data, computational models for the atmospheric transport of aerosols, and models for combustion and for energy utilization. The CSC was formed to bring together

  3. The Telemetry Agile Manufacturing Effort

    SciTech Connect

    Brown, K.D.

    1995-01-01

    The Telemetry Agile Manufacturing Effort (TAME) is an agile enterprising demonstration sponsored by the US Department of Energy (DOE). The project experimented with new approaches to product realization and assessed their impacts on performance, cost, flow time, and agility. The purpose of the project was to design the electrical and mechanical features of an integrated telemetry processor, establish the manufacturing processes, and produce an initial production lot of two to six units. This paper outlines the major methodologies utilized by the TAME, describes the accomplishments that can be attributed to each methodology, and finally, examines the lessons learned and explores the opportunities for improvement associated with the overall effort. The areas for improvement are discussed relative to an ideal vision of the future for agile enterprises. By the end of the experiment, the TAME reduced production flow time by approximately 50% and life cycle cost by more than 30%. Product performance was improved compared with conventional DOE production approaches.

  4. Computational electronics and electromagnetics

    SciTech Connect

    Shang, C. C.

    1997-02-01

    The Computational Electronics and Electromagnetics thrust area at Lawrence Livermore National Laboratory serves as the focal point for engineering R&D activities for developing computer-based design, analysis, and tools for theory. Key representative applications include design of particle accelerator cells and beamline components; engineering analysis and design of high-power components, photonics, and optoelectronics circuit design; EMI susceptibility analysis; and antenna synthesis. The FY-96 technology-base effort focused code development on (1) accelerator design codes; (2) 3-D massively parallel, object-oriented time-domain EM codes; (3) material models; (4) coupling and application of engineering tools for analysis and design of high-power components; (5) 3-D spectral-domain CEM tools; and (6) enhancement of laser drilling codes. Joint efforts with the Power Conversion Technologies thrust area include development of antenna systems for compact, high-performance radar, in addition to novel, compact Marx generators. 18 refs., 25 figs., 1 tab.

  5. Computational studies on the interactions among redox couples, additives and TiO2: implications for dye-sensitized solar cells.

    PubMed

    Asaduzzaman, Abu Md; Schreckenbach, Georg

    2010-11-21

    One of the major and unique components of dye-sensitized solar cells (DSSC) is the iodide/triiodide redox couple. Periodic density-functional calculations have been carried out to study the interactions among three different components of the DSSC, i.e. the redox shuttle, the TiO(2) semiconductor surface, and nitrogen containing additives, with a focus on the implications for the performance of the DSSC. Iodide and bromide with alkali metal cations as counter ions are strongly adsorbed on the TiO(2) surface. Small additive molecules also strongly interact with TiO(2). Both interactions induce a negative shift of the Fermi energy of TiO(2). The negative shift of the Fermi energy is related to the performance of the cell by increasing the open voltage of the cell and retarding the injection dynamics (decreasing the short circuit current). Additive molecules, however, have relatively weaker interaction with iodide and triiodide.

  6. Characterization of pulmonary nodules on computer tomography (CT) scans: the effect of additive white noise on features selection and classification performance

    NASA Astrophysics Data System (ADS)

    Osicka, Teresa; Freedman, Matthew T.; Ahmed, Farid

    2007-03-01

    The goal of this project is to use computer analysis to classify small lung nodules, identified on CT, into likely benign and likely malignant categories. We compared discrete wavelet transforms (DWT) based features and a modification of classical features used and reported by others. To determine the best combination of features for classification, several intensities of white noise were added to the original images to determine the effect of such noise on classification accuracy. Two different approaches were used to determine the effect of noise: in the first method the best features for classification of nodules on the original image were retained as noise was added. In the second approach, we recalculated the results to reselect the best classification features for each particular level of added noise. The CT images are from the National Lung Screening Trial (NLST) of the National Cancer Institute (NCI). For this study, nodules were extracted in window frames of three sizes. Malignant nodules were cytologically or histogically diagnosed, while benign had two-year follow-up. A linear discriminant analysis with Fisher criterion (FLDA) approach was used for feature selection and classification, and decision matrix for matched sample to compare the classification accuracy. The initial features mode revealed sensitivity to both the amount of noise and the size of window frame. The recalculated feature mode proved more robust to noise with no change in terms of classification accuracy. This indicates that the best features for computer classification of lung nodules will differ with noise, and, therefore, with exposure.

  7. Comprehensive cardiac assessment with multislice computed tomography: evaluation of left ventricular function and perfusion in addition to coronary anatomy in patients with previous myocardial infarction

    PubMed Central

    Henneman, M M; Schuijf, J D; Jukema, J W; Lamb, H J; de Roos, A; Dibbets, P; Stokkel, M P; van der Wall, E E; Bax, J J

    2006-01-01

    Objective To evaluate a comprehensive multislice computed tomography (MSCT) protocol in patients with previous infarction, including assessment of coronary artery stenoses, left ventricular (LV) function and perfusion. Patients and methods 16‐slice MSCT was performed in 21 patients with previous infarction; from the MSCT data, coronary artery stenoses, (regional and global) LV function and perfusion were assessed. Invasive coronary angiography and gated single‐photon emission computed tomography (SPECT) served as the reference standards for coronary artery stenoses and LV function/perfusion, respectively. Results 236 of 241 (98%) coronary artery segments were interpretable on MSCT. The sensitivity and specificity for detection of stenoses were 91% and 97%. Pearson's correlation showed excellent agreement for assessment of LV ejection fraction between MSCT and SPECT (49 (13)% v 53 (12)%, respectively, r  =  0.85). Agreement for assessment of regional wall motion was excellent (92%, κ  =  0.77). In 68 of 73 (93%) segments, MSCT correctly identified a perfusion defect as compared with SPECT, whereas the absence of perfusion defects was correctly detected in 277 of 284 (98%) segments. Conclusions MSCT permits accurate, non‐invasive assessment of coronary artery stenoses, LV function and perfusion in patients with previous infarction. All parameters can be assessed from a single dataset. PMID:16740917

  8. Food additives

    MedlinePlus

    ... or natural. Natural food additives include: Herbs or spices to add flavor to foods Vinegar for pickling ... Certain colors improve the appearance of foods. Many spices, as well as natural and man-made flavors, ...

  9. Respiratory effort correction strategies to improve the reproducibility of lung expansion measurements

    SciTech Connect

    Du, Kaifang; Reinhardt, Joseph M.; Christensen, Gary E.; Ding, Kai; Bayouth, John E.

    2013-12-15

    Purpose: Four-dimensional computed tomography (4DCT) can be used to make measurements of pulmonary function longitudinally. The sensitivity of such measurements to identify change depends on measurement uncertainty. Previously, intrasubject reproducibility of Jacobian-based measures of lung tissue expansion was studied in two repeat prior-RT 4DCT human acquisitions. Difference in respiratory effort such as breathing amplitude and frequency may affect longitudinal function assessment. In this study, the authors present normalization schemes that correct ventilation images for variations in respiratory effort and assess the reproducibility improvement after effort correction.Methods: Repeat 4DCT image data acquired within a short time interval from 24 patients prior to radiation therapy (RT) were used for this analysis. Using a tissue volume preserving deformable image registration algorithm, Jacobian ventilation maps in two scanning sessions were computed and compared on the same coordinate for reproducibility analysis. In addition to computing the ventilation maps from end expiration to end inspiration, the authors investigated the effort normalization strategies using other intermediated inspiration phases upon the principles of equivalent tidal volume (ETV) and equivalent lung volume (ELV). Scatter plots and mean square error of the repeat ventilation maps and the Jacobian ratio map were generated for four conditions: no effort correction, global normalization, ETV, and ELV. In addition, gamma pass rate was calculated from a modified gamma index evaluation between two ventilation maps, using acceptance criterions of 2 mm distance-to-agreement and 5% ventilation difference.Results: The pattern of regional pulmonary ventilation changes as lung volume changes. All effort correction strategies improved reproducibility when changes in respiratory effort were greater than 150 cc (p < 0.005 with regard to the gamma pass rate). Improvement of reproducibility was

  10. New Horizons Launch Contingency Effort

    NASA Astrophysics Data System (ADS)

    Chang, Yale; Lear, Matthew H.; McGrath, Brian E.; Heyler, Gene A.; Takashima, Naruhisa; Owings, W. Donald

    2007-01-01

    On 19 January 2006 at 2:00 PM EST, the NASA New Horizons spacecraft (SC) was launched from the Cape Canaveral Air Force Station (CCAFS), FL, onboard an Atlas V 551/Centaur/STAR™ 48B launch vehicle (LV) on a mission to explore the Pluto Charon planetary system and possibly other Kuiper Belt Objects. It carried a single Radioisotope Thermoelectric Generator (RTG). As part of the joint NASA/US Department of Energy (DOE) safety effort, contingency plans were prepared to address the unlikely events of launch accidents leading to a near-pad impact, a suborbital reentry, an orbital reentry, or a heliocentric orbit. As the implementing organization. The Johns Hopkins University Applied Physics Laboratory (JHU/APL) had expanded roles in the New Horizons launch contingency effort over those for the Cassini mission and Mars Exploration Rovers missions. The expanded tasks included participation in the Radiological Control Center (RADCC) at the Kennedy Space Center (KSC), preparation of contingency plans, coordination of space tracking assets, improved aerodynamics characterization of the RTG's 18 General Purpose Heat Source (GPHS) modules, and development of spacecraft and RTG reentry breakup analysis tools. Other JHU/APL tasks were prediction of the Earth impact footprints (ElFs) for the GPHS modules released during the atmospheric reentry (for purposes of notification and recovery), prediction of the time of SC reentry from a potential orbital decay, pre-launch dissemination of ballistic coefficients of various possible reentry configurations, and launch support of an Emergency Operations Center (EOC) on the JHU/APL campus. For the New Horizons launch, JHU/APL personnel at the RADCC and at the EOC were ready to implement any real-time launch contingency activities. A successful New Horizons launch and interplanetary injection precluded any further contingency actions. The New Horizons launch contingency was an interagency effort by several organizations. This paper

  11. 20 CFR 632.123 - Maintenance of effort.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Maintenance of effort. 632.123 Section 632.123 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INDIAN AND NATIVE... effort. (a) Funds provided under this Act shall only be used for activities which are in addition...

  12. Computer modelling integrated with micro-CT and material testing provides additional insight to evaluate bone treatments: Application to a beta-glycan derived whey protein mice model.

    PubMed

    Sreenivasan, D; Tu, P T; Dickinson, M; Watson, M; Blais, A; Das, R; Cornish, J; Fernandez, J

    2016-01-01

    The primary aim of this study was to evaluate the influence of a whey protein diet on computationally predicted mechanical strength of murine bones in both trabecular and cortical regions of the femur. There was no significant influence on mechanical strength in cortical bone observed with increasing whey protein treatment, consistent with cortical tissue mineral density (TMD) and bone volume changes observed. Trabecular bone showed a significant decline in strength with increasing whey protein treatment when nanoindentation derived Young׳s moduli were used in the model. When microindentation, micro-CT phantom density or normalised Young׳s moduli were included in the model a non-significant decline in strength was exhibited. These results for trabecular bone were consistent with both trabecular bone mineral density (BMD) and micro-CT indices obtained independently. The secondary aim of this study was to characterise the influence of different sources of Young׳s moduli on computational prediction. This study aimed to quantify the predicted mechanical strength in 3D from these sources and evaluate if trends and conclusions remained consistent. For cortical bone, predicted mechanical strength behaviour was consistent across all sources of Young׳s moduli. There was no difference in treatment trend observed when Young׳s moduli were normalised. In contrast, trabecular strength due to whey protein treatment significantly reduced when material properties from nanoindentation were introduced. Other material property sources were not significant but emphasised the strength trend over normalised material properties. This shows strength at the trabecular level was attributed to both changes in bone architecture and material properties.

  13. Learning to Understand Natural Language with Less Human Effort

    DTIC Science & Technology

    2015-05-01

    Learning to Understand Natural Language with Less Human Effort Jayant Krishnamurthy CMU-CS-15-110 May 2015 School of Computer Science Carnegie Mellon...COVERED 00-00-2015 to 00-00-2015 4. TITLE AND SUBTITLE Learning to Understand Natural Language with Less Human Effort 5a. CONTRACT NUMBER 5b...require less human annotation are necessary in order to learn to understand natural language in these more challenging settings. This thesis explores

  14. APS Education and Diversity Efforts

    NASA Astrophysics Data System (ADS)

    Prestridge, Katherine; Hodapp, Theodore

    2015-11-01

    American Physical Society (APS) has a wide range of education and diversity programs and activities, including programs that improve physics education, increase diversity, provide outreach to the public, and impact public policy. We present the latest programs spearheaded by the Committee on the Status of Women in Physics (CSWP), with highlights from other diversity and education efforts. The CSWP is working to increase the fraction of women in physics, understand and implement solutions for gender-specific issues, enhance professional development opportunities for women in physics, and remedy issues that impact gender inequality in physics. The Conferences for Undergraduate Women in Physics, Professional Skills Development Workshops, and our new Professional Skills program for students and postdocs are all working towards meeting these goals. The CSWP also has site visit and conversation visit programs, where department chairs request that the APS assess the climate for women in their departments or facilitate climate discussions. APS also has two significant programs to increase participation by underrepresented minorities (URM). The newest program, the APS National Mentoring Community, is working to provide mentoring to URM undergraduates, and the APS Bridge Program is an established effort that is dramatically increasing the number of URM PhDs in physics.

  15. Do We Really Need Additional Contrast-Enhanced Abdominal Computed Tomography for Differential Diagnosis in Triage of Middle-Aged Subjects With Suspected Biliary Pain

    PubMed Central

    Hwang, In Kyeom; Lee, Yoon Suk; Kim, Jaihwan; Lee, Yoon Jin; Park, Ji Hoon; Hwang, Jin-Hyeok

    2015-01-01

    Abstract Enhanced computed tomography (CT) is widely used for evaluating acute biliary pain in the emergency department (ED). However, concern about radiation exposure from CT has also increased. We investigated the usefulness of pre-contrast CT for differential diagnosis in middle-aged subjects with suspected biliary pain. A total of 183 subjects, who visited the ED for suspected biliary pain from January 2011 to December 2012, were included. Retrospectively, pre-contrast phase and multiphase CT findings were reviewed and the detection rate of findings suggesting disease requiring significant treatment by noncontrast CT (NCCT) was compared with cases detected by multiphase CT. Approximately 70% of total subjects had a significant condition, including 1 case of gallbladder cancer and 126 (68.8%) cases requiring intervention (122 biliary stone-related diseases, 3 liver abscesses, and 1 liver hemangioma). The rate of overlooking malignancy without contrast enhancement was calculated to be 0% to 1.5%. Biliary stones and liver space-occupying lesions were found equally on NCCT and multiphase CT. Calculated probable rates of overlooking acute cholecystitis and biliary obstruction were maximally 6.8% and 4.2% respectively. Incidental significant finding unrelated with pain consisted of 1 case of adrenal incidentaloma, which was also observed in NCCT. NCCT might be sufficient to detect life-threatening or significant disease requiring early treatment in young adults with biliary pain. PMID:25700321

  16. Decreased length of stay after addition of healthcare provider in emergency department triage: a comparison between computer-simulated and real-world interventions

    PubMed Central

    Al-Roubaie, Abdul Rahim; Goldlust, Eric Jonathan

    2013-01-01

    Objective (1) To determine the effects of adding a provider in triage on average length of stay (LOS) and proportion of patients with >6 h LOS. (2) To assess the accuracy of computer simulation in predicting the magnitude of such effects on these metrics. Methods A group-level quasi-experimental trial comparing the St. Louis Veterans Affairs Medical Center emergency department (1) before intervention, (2) after institution of provider in triage, and discrete event simulation (DES) models of similar (3) ‘before’ and (4) ‘after’ conditions. The outcome measures were daily mean LOS and percentage of patients with LOS >6 h. Results The DES-modelled intervention predicted a decrease in the %6-hour LOS from 19.0% to 13.1%, and a drop in the daily mean LOS from 249 to 200 min (p<0.0001). Following (actual) intervention, the number of patients with LOS >6 h decreased from 19.9% to 14.3% (p<0.0001), with the daily mean LOS decreasing from 247 to 210 min (p<0.0001). Conclusion Physician and mid-level provider coverage at triage significantly reduced emergency department LOS in this setting. DES accurately predicted the magnitude of this effect. These results suggest further work in the generalisability of triage providers and in the utility of DES for predicting quantitative effects of process changes. PMID:22398851

  17. An opportunity cost model of subjective effort and task performance

    PubMed Central

    Kurzban, Robert; Duckworth, Angela; Kable, Joseph W.; Myers, Justus

    2013-01-01

    Why does performing certain tasks cause the aversive experience of mental effort and concomitant deterioration in task performance? One explanation posits a physical resource that is depleted over time. We propose an alternate explanation that centers on mental representations of the costs and benefits associated with task performance. Specifically, certain computational mechanisms, especially those associated with executive function, can be deployed for only a limited number of simultaneous tasks at any given moment. Consequently, the deployment of these computational mechanisms carries an opportunity cost – that is, the next-best use to which these systems might be put. We argue that the phenomenology of effort can be understood as the felt output of these cost/benefit computations. In turn, the subjective experience of effort motivates reduced deployment of these computational mechanisms in the service of the present task. These opportunity cost representations, then, together with other cost/benefit calculations, determine effort expended and, everything else equal, result in performance reductions. In making our case for this position, we review alternate explanations both for the phenomenology of effort associated with these tasks and for performance reductions over time. Likewise, we review the broad range of relevant empirical results from across subdisciplines, especially psychology and neuroscience. We hope that our proposal will help to build links among the diverse fields that have been addressing similar questions from different perspectives, and we emphasize ways in which alternate models might be empirically distinguished. PMID:24304775

  18. Energy Drain by Computers Stifles Efforts at Cost Control

    ERIC Educational Resources Information Center

    Keller, Josh

    2009-01-01

    The high price of storing and processing data is hurting colleges and universities across the country. In response, some institutions are embracing greener technologies to keep costs down and help the environment. But compared with other industries, colleges and universities have been slow to understand the problem and to adopt energy-saving…

  19. Potlining Additives

    SciTech Connect

    Rudolf Keller

    2004-08-10

    In this project, a concept to improve the performance of aluminum production cells by introducing potlining additives was examined and tested. Boron oxide was added to cathode blocks, and titanium was dissolved in the metal pool; this resulted in the formation of titanium diboride and caused the molten aluminum to wet the carbonaceous cathode surface. Such wetting reportedly leads to operational improvements and extended cell life. In addition, boron oxide suppresses cyanide formation. This final report presents and discusses the results of this project. Substantial economic benefits for the practical implementation of the technology are projected, especially for modern cells with graphitized blocks. For example, with an energy savings of about 5% and an increase in pot life from 1500 to 2500 days, a cost savings of $ 0.023 per pound of aluminum produced is projected for a 200 kA pot.

  20. Phosphazene additives

    DOEpatents

    Harrup, Mason K; Rollins, Harry W

    2013-11-26

    An additive comprising a phosphazene compound that has at least two reactive functional groups and at least one capping functional group bonded to phosphorus atoms of the phosphazene compound. One of the at least two reactive functional groups is configured to react with cellulose and the other of the at least two reactive functional groups is configured to react with a resin, such as an amine resin of a polycarboxylic acid resin. The at least one capping functional group is selected from the group consisting of a short chain ether group, an alkoxy group, or an aryloxy group. Also disclosed are an additive-resin admixture, a method of treating a wood product, and a wood product.

  1. Regulatory use of computational toxicology tools and databases at the United States Food and Drug Administration's Office of Food Additive Safety.

    PubMed

    Arvidson, Kirk B; Chanderbhan, Ronald; Muldoon-Jacobs, Kristi; Mayer, Julie; Ogungbesan, Adejoke

    2010-07-01

    Over 10 years ago, the Office of Food Additive Safety (OFAS) in the FDA's Center for Food Safety and Applied Nutrition implemented the formal use of structure-activity relationship analysis and quantitative structure-activity relationship (QSAR) analysis in the premarket review of food-contact substances. More recently, OFAS has implemented the use of multiple QSAR software packages and has begun investigating the use of metabolism data and metabolism predictive models in our QSAR evaluations of food-contact substances. In this article, we provide an overview of the programs used in OFAS as well as a perspective on how to apply multiple QSAR tools in the review process of a new food-contact substance.

  2. Computer simulation for the growing probability of additional offspring with an advantageous reversal allele in the decoupled continuous-time mutation-selection model

    NASA Astrophysics Data System (ADS)

    Gill, Wonpyong

    2016-01-01

    This study calculated the growing probability of additional offspring with the advantageous reversal allele in an asymmetric sharply-peaked landscape using the decoupled continuous-time mutation-selection model. The growing probability was calculated for various population sizes, N, sequence lengths, L, selective advantages, s, fitness parameters, k and measuring parameters, C. The saturated growing probability in the stochastic region was approximately the effective selective advantage, s*, when C≫1/Ns* and s*≪1. The present study suggests that the growing probability in the stochastic region in the decoupled continuous-time mutation-selection model can be described using the theoretical formula for the growing probability in the Moran two-allele model. The selective advantage ratio, which represents the ratio of the effective selective advantage to the selective advantage, does not depend on the population size, selective advantage, measuring parameter and fitness parameter; instead the selective advantage ratio decreases with the increasing sequence length.

  3. Visual Computing Environment Workshop

    NASA Technical Reports Server (NTRS)

    Lawrence, Charles (Compiler)

    1998-01-01

    The Visual Computing Environment (VCE) is a framework for intercomponent and multidisciplinary computational simulations. Many current engineering analysis codes simulate various aspects of aircraft engine operation. For example, existing computational fluid dynamics (CFD) codes can model the airflow through individual engine components such as the inlet, compressor, combustor, turbine, or nozzle. Currently, these codes are run in isolation, making intercomponent and complete system simulations very difficult to perform. In addition, management and utilization of these engineering codes for coupled component simulations is a complex, laborious task, requiring substantial experience and effort. To facilitate multicomponent aircraft engine analysis, the CFD Research Corporation (CFDRC) is developing the VCE system. This system, which is part of NASA's Numerical Propulsion Simulation System (NPSS) program, can couple various engineering disciplines, such as CFD, structural analysis, and thermal analysis.

  4. A specific role for serotonin in overcoming effort cost.

    PubMed

    Meyniel, Florent; Goodwin, Guy M; Deakin, Jf William; Klinge, Corinna; MacFadyen, Christine; Milligan, Holly; Mullings, Emma; Pessiglione, Mathias; Gaillard, Raphaël

    2016-11-08

    Serotonin is implicated in many aspects of behavioral regulation. Theoretical attempts to unify the multiple roles assigned to serotonin proposed that it regulates the impact of costs, such as delay or punishment, on action selection. Here, we show that serotonin also regulates other types of action costs such as effort. We compared behavioral performance in 58 healthy humans treated during 8 weeks with either placebo or the selective serotonin reuptake inhibitor escitalopram. The task involved trading handgrip force production against monetary benefits. Participants in the escitalopram group produced more effort and thereby achieved a higher payoff. Crucially, our computational analysis showed that this effect was underpinned by a specific reduction of effort cost, and not by any change in the weight of monetary incentives. This specific computational effect sheds new light on the physiological role of serotonin in behavioral regulation and on the clinical effect of drugs for depression.

  5. Rain Hampers Tsunami Relief Efforts

    NASA Technical Reports Server (NTRS)

    2005-01-01

    The cleanup and relief efforts from the recent tsunamis continue in coastal communities that were ravaged by the waves all across the Indian Ocean. Heavy rains have further complicated the matter and added to the misery in parts of eastern Sri Lanka. Between December 28, 2004, and January 5, 2005, up to 10 to 15 inches of rain may have fallen along the southeast coast of the island, and as much as 20 inches (red areas) fell just offshore. This rainfall map was created by the TRMM-based, near-real time Multi-satellite Precipitation Analysis (MPA) at the NASA Goddard Space Flight Center, which monitors rainfall over the global tropics. The map shows that many other regions around the Indian Ocean were also affected by the rains, including Malaysia and parts of Sumatra. The heaviest rains fell on December 31 and January 4. The rains were likely the result of a combination of the northeast monsoon interacting with the topography and an active phase of what is known as the Madden-Julian Oscillation (MJO) (or 30-60 day oscillation). The MJO is a large-scale disturbance that propagates eastward from the Indian Ocean into the West Pacific Ocean, bringing extended periods of unsettled weather with it. Individual convective complexes within the MJO can last on the order of a day. TRMM is a joint mission between NASA and the Japanese space agency JAXA. NASA image produced by Hal Pierce (SSAI/NASA GSFC) and caption by Steve Lang (SSAI/NASA GSFC).

  6. Perception of effort in Exercise Science: Definition, measurement and perspectives.

    PubMed

    Pageaux, Benjamin

    2016-11-01

    Perception of effort, also known as perceived exertion or sense of effort, can be described as a cognitive feeling of work associated with voluntary actions. The aim of the present review is to provide an overview of what is perception of effort in Exercise Science. Due to the addition of sensations other than effort in its definition, the neurophysiology of perceived exertion remains poorly understood. As humans have the ability to dissociate effort from other sensations related to physical exercise, the need to use a narrower definition is emphasised. Consequently, a definition and some brief guidelines for its measurement are provided. Finally, an overview of the models present in the literature aiming to explain its neurophysiology, and some perspectives for future research are offered.

  7. Measuring and Modeling Change in Examinee Effort on Low-Stakes Tests across Testing Occasions

    ERIC Educational Resources Information Center

    Sessoms, John; Finney, Sara J.

    2015-01-01

    Because schools worldwide use low-stakes tests to make important decisions, value-added indices computed from test scores must accurately reflect student learning, which requires equal test-taking effort across testing occasions. Evaluating change in effort assumes effort is measured equivalently across occasions. We evaluated the longitudinal…

  8. 42 CFR 441.181 - Maintenance of effort: Explanation of terms and requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Maintenance of effort: Explanation of terms and... Facilities or Programs § 441.181 Maintenance of effort: Explanation of terms and requirements. (a) For... sections in the current quarter, must be included in the maintenance of effort computation if, during...

  9. The Computer Fraud and Abuse Act of 1986. Hearing before the Committee on the Judiciary, United States Senate, Ninety-Ninth Congress, Second Session on S.2281, a Bill To Amend Title 18, United States Code, To Provide Additional Penalties for Fraud and Related Activities in Connection with Access Devices and Computers, and for Other Purposes.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Committee on the Judiciary.

    The proposed legislation--S. 2281--would amend federal laws to provide additional penalties for fraud and related activities in connection with access devices and computers. The complete text of the bill and proceedings of the hearing are included in this report. Statements and materials submitted by the following committee members and witnesses…

  10. Spectral analysis of sinus arrhythmia - A measure of mental effort

    NASA Technical Reports Server (NTRS)

    Vicente, Kim J.; Craig Thornton, D.; Moray, Neville

    1987-01-01

    The validity of the spectral analysis of sinus arrhythmia as a measure of mental effort was investigated using a computer simulation of a hovercraft piloted along a river as the experimental task. Strong correlation was observed between the subjective effort-ratings and the heart-rate variability (HRV) power spectrum between 0.06 and 0.14 Hz. Significant correlations were observed not only between subjects but, more importantly, within subjects as well, indicating that the spectral analysis of HRV is an accurate measure of the amount of effort being invested by a subject. Results also indicate that the intensity of effort invested by subjects cannot be inferred from the objective ratings of task difficulty or from performance.

  11. Reminiscing about 15 years of interoperability efforts

    DOE PAGES

    Van de Sompel, Herbert; Nelson, Michael L.

    2015-11-01

    Over the past fifteen years, our perspective on tackling information interoperability problems for web-based scholarship has evolved significantly. In this opinion piece, we look back at three efforts that we have been involved in that aptly illustrate this evolution: OAI-PMH, OAI-ORE, and Memento. Understanding that no interoperability specification is neutral, we attempt to characterize the perspectives and technical toolkits that provided the basis for these endeavors. With that regard, we consider repository-centric and web-centric interoperability perspectives, and the use of a Linked Data or a REST/HATEAOS technology stack, respectively. In addition, we lament the lack of interoperability across nodes thatmore » play a role in web-based scholarship, but end on a constructive note with some ideas regarding a possible path forward.« less

  12. Reminiscing about 15 years of interoperability efforts

    SciTech Connect

    Van de Sompel, Herbert; Nelson, Michael L.

    2015-11-01

    Over the past fifteen years, our perspective on tackling information interoperability problems for web-based scholarship has evolved significantly. In this opinion piece, we look back at three efforts that we have been involved in that aptly illustrate this evolution: OAI-PMH, OAI-ORE, and Memento. Understanding that no interoperability specification is neutral, we attempt to characterize the perspectives and technical toolkits that provided the basis for these endeavors. With that regard, we consider repository-centric and web-centric interoperability perspectives, and the use of a Linked Data or a REST/HATEAOS technology stack, respectively. In addition, we lament the lack of interoperability across nodes that play a role in web-based scholarship, but end on a constructive note with some ideas regarding a possible path forward.

  13. DC Control Effort Minimized for Magnetic-Bearing-Supported Shaft

    NASA Technical Reports Server (NTRS)

    Brown, Gerald V.

    2001-01-01

    A magnetic-bearing-supported shaft may have a number of concentricity and alignment problems. One of these involves the relationship of the position sensors, the centerline of the backup bearings, and the magnetic center of the magnetic bearings. For magnetic bearings with permanent magnet biasing, the average control current for a given control axis that is not bearing the shaft weight will be minimized if the shaft is centered, on average over a revolution, at the magnetic center of the bearings. That position may not yield zero sensor output or center the shaft in the backup bearing clearance. The desired shaft position that gives zero average current can be achieved if a simple additional term is added to the control law. Suppose that the instantaneous control currents from each bearing are available from measurements and can be input into the control computer. If each control current is integrated with a very small rate of accumulation and the result is added to the control output, the shaft will gradually move to a position where the control current averages to zero over many revolutions. This will occur regardless of any offsets of the position sensor inputs. At that position, the average control effort is minimized in comparison to other possible locations of the shaft. Nonlinearities of the magnetic bearing are minimized at that location as well.

  14. Is the coefficient of variation a valid measure for detecting sincerity of effort of grip strength?

    PubMed

    Shechtman, Orit

    1999-01-01

    The wide use of the coefficient of variation in detecting sincerity of effort is puzzling since existing research findings regarding its effectiveness are contradictory. The lack of empirical support in the literature raises the question of whether or not the coefficient of variation is a valid measure for detecting sincerity of effort. Many clinicians, especially those who use a computer software to calculate the coefficient of variation, may not understand how the coefficient of variation is derived and what it is based on. The coefficient of variation is a measure of relative variability and would be used correctly only if the average and the standard deviation of grip strength trials increased proportionally. This case study, however, demonstrated that the average and standard deviation of grip strength are independent. Thus, the coefficient of variation is not a valid measure of sincerity of effort. In addition, this study indicated that the coefficient of variation may be inflated in individuals after carpal tunnel release surgery. The author, therefore, cautions clinicians against the use of the coefficient of variation as a measure of sincerity of effort especially in injured individuals with compromised hand strength.

  15. Computer Guerrillas.

    ERIC Educational Resources Information Center

    Immel, A. Richard

    1983-01-01

    Describes several cases in which microcomputers were used to prevent large organizations (e.g., utility companies, U.S. Government Forestry Commission) from carrying out actions considered not to be in the public's best interests. The use of the computers by social activitists in their efforts to halt environmental destruction is discussed. (EAO)

  16. Measuring collections effort improves cash performance.

    PubMed

    Shutts, Joe

    2009-09-01

    Having a satisfied work force can lead to an improved collections effort. Hiring the right people and training them ensures employee engagement. Measuring collections effort and offering incentives is key to revenue cycle success.

  17. [Delayed post effort muscle soreness].

    PubMed

    Coudreuse, J M; Dupont, P; Nicol, C

    2004-08-01

    Muscle intolerance to exercise may result from different processes. Diagnosis involves confirming first the source of pain, then potential pathological myalgia. Delayed-onset muscle soreness (DOMS), commonly referred as tiredness, occurs frequently in sport. DOMS usually develops 12-48 h after intensive and/or unusual eccentric muscle action. Symptoms usually involve the quadriceps muscle group but may also affect the hamstring and triceps surae groups. The muscles are sensitive to palpation, contraction and passive stretch. Acidosis, muscle spasm and microlesions in both connective and muscle tissues may explain the symptoms. However, inflammation appears to be the most common explanation. Interestingly, there is strong evidence that the progression of the exercise-induced muscle injury proceeds no further in the absence of inflammation. Even though unpleasant, DOMS should not be considered as an indicator of muscle damage but, rather, a sign of the regenerative process, which is well known to contribute to the increased muscle mass. DOMS can be associated with decreased proprioception and range of motion, as well as maximal force and activation. DOMS disappears 2-10 days before complete functional recovery. This painless period is ripe for additional joint injuries. Similarly, if some treatments are well known to attenuate DOMS, none has been demonstrated to accelerate either structural or functional recovery. In terms of the role of the inflammatory process, these treatments might even delay overall recovery.

  18. Using a cloud to replenish parched groundwater modeling efforts

    USGS Publications Warehouse

    Hunt, Randall J.; Luchette, Joseph; Schreuder, Willem A.; Rumbaugh, James O.; Doherty, John; Tonkin, Matthew J.; Rumbaugh, Douglas B.

    2010-01-01

    Groundwater models can be improved by introduction of additional parameter flexibility and simultaneous use of soft-knowledge. However, these sophisticated approaches have high computational requirements. Cloud computing provides unprecedented access to computing power via the Internet to facilitate the use of these techniques. A modeler can create, launch, and terminate “virtual” computers as needed, paying by the hour, and save machine images for future use. Such cost-effective and flexible computing power empowers groundwater modelers to routinely perform model calibration and uncertainty analysis in ways not previously possible.

  19. Pupil size variations correlate with physical effort perception.

    PubMed

    Zénon, Alexandre; Sidibé, Mariam; Olivier, Etienne

    2014-01-01

    It has long been established that the pupil diameter increases during mental activities in proportion to the difficulty of the task at hand. However, it is still unclear whether this relationship between the pupil size and effort applies also to physical effort. In order to address this issue, we asked healthy volunteers to perform a power grip task, at varied intensity, while evaluating their effort both implicitly and explicitly, and while concurrently monitoring their pupil size. Each trial started with a contraction of imposed intensity, under the control of a continuous visual feedback. Upon completion of the contraction, participants had to choose whether to replicate, without feedback, the first contraction for a variable monetary reward, or whether to skip this step and go directly to the next trial. The rate of acceptance of effort replication and the amount of force exerted during the replication were used as implicit measures of the perception of the effort exerted during the first contraction. In addition, the participants were asked to rate on an analog scale, their explicit perception of the effort for each intensity condition. We found that pupil diameter increased during physical effort and that the magnitude of this response reflected not only the actual intensity of the contraction but also the subjects' perception of the effort. This finding indicates that the pupil size signals the level of effort invested in a task, irrespective of whether it is physical or mental. It also helps refining the potential brain circuits involved since the results of the current study imply a convergence of mental and physical effort information at some level along this pathway.

  20. A compendium of computational fluid dynamics at the Langley Research Center

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Through numerous summary examples, the scope and general nature of the computational fluid dynamics (CFD) effort at Langley is identified. These summaries will help inform researchers in CFD and line management at Langley of the overall effort. In addition to the inhouse efforts, out of house CFD work supported by Langley through industrial contracts and university grants are included. Researchers were encouraged to include summaries of work in preliminary and tentative states of development as well as current research approaching definitive results.

  1. An investigation on the effect of second-order additional thickness distributions to the upper surface of an NACA 64 sub 1-212 airfoil. [using flow equations and a CDC 7600 digital computer

    NASA Technical Reports Server (NTRS)

    Hague, D. S.; Merz, A. W.

    1975-01-01

    An investigation was conducted on a CDC 7600 digital computer to determine the effects of additional thickness distributions to the upper surface of an NACA 64 sub 1 - 212 airfoil. Additional thickness distributions employed were in the form of two second-order polynomial arcs which have a specified thickness at a given chordwise location. The forward arc disappears at the airfoil leading edge, the aft arc disappears at the airfoil trailing edge. At the juncture of the two arcs, x = x, continuity of slope is maintained. The effect of varying the maximum additional thickness and its chordwise location on airfoil lift coefficient, pitching moment, and pressure distribution was investigated. Results were obtained at a Mach number of 0.2 with an angle-of-attack of 6 degrees on the basic NACA 64 sub 1 - 212 airfoil, and all calculations employ the full potential flow equations for two dimensional flow. The relaxation method of Jameson was employed for solution of the potential flow equations.

  2. Theoretical effect of modifications to the upper surface of two NACA airfoils using smooth polynomial additional thickness distributions which emphasize leading edge profile and which vary quadratically at the trailing edge. [using flow equations and a CDC 7600 computer

    NASA Technical Reports Server (NTRS)

    Merz, A. W.; Hague, D. S.

    1975-01-01

    An investigation was conducted on a CDC 7600 digital computer to determine the effects of additional thickness distributions to the upper surface of the NACA 64-206 and 64 sub 1 - 212 airfoils. The additional thickness distribution had the form of a continuous mathematical function which disappears at both the leading edge and the trailing edge. The function behaves as a polynomial of order epsilon sub 1 at the leading edge, and a polynomial of order epsilon sub 2 at the trailing edge. Epsilon sub 2 is a constant and epsilon sub 1 is varied over a range of practical interest. The magnitude of the additional thickness, y, is a second input parameter, and the effect of varying epsilon sub 1 and y on the aerodynamic performance of the airfoil was investigated. Results were obtained at a Mach number of 0.2 with an angle-of-attack of 6 degrees on the basic airfoils, and all calculations employ the full potential flow equations for two dimensional flow. The relaxation method of Jameson was employed for solution of the potential flow equations.

  3. An investigation on the effect of second-order additional thickness distributions to the upper surface of an NACA 64-206 airfoil. [using flow equations and a CDC 7600 digital computer

    NASA Technical Reports Server (NTRS)

    Merz, A. W.; Hague, D. S.

    1975-01-01

    An investigation was conducted on a CDC 7600 digital computer to determine the effects of additional thickness distributions to the upper surface of an NACA 64-206 airfoil. Additional thickness distributions employed were in the form of two second-order polynomial arcs which have a specified thickness at a given chordwise location. The forward arc disappears at the airfoil leading edge, the aft arc disappears at the airfoil trailing edge. At the juncture of the two arcs, x = x, continuity of slope is maintained. The effect of varying the maximum additional thickness and its chordwise location on airfoil lift coefficient, pitching moment, and pressure distribution was investigated. Results were obtained at a Mach number of 0.2 with an angle-of-attack of 6 degrees on the basic NACA 64-206 airfoil, and all calculations employ the full potential flow equations for two dimensional flow. The relaxation method of Jameson was employed for solution of the potential flow equations.

  4. RBANS embedded measures of suboptimal effort in dementia: effort scale has a lower failure rate than the effort index.

    PubMed

    Burton, Rachel L; Enright, Joe; O'Connell, Megan E; Lanting, Shawnda; Morgan, Debra

    2015-02-01

    The importance of evaluating effort in neuropsychological assessments has been widely acknowledged, but measuring effort in the context of dementia remains challenging due to the impact of dementia severity on effort measure scores. Two embedded measures have been developed for the repeatable battery for the assessment of neuropsychological status (RBANS; Randolph, C., Tierney, M. C., Mohr, E., & Chase, T. N. (1998). The repeatable battery for the assessment of neuropsychological status (RBANS): Preliminary clinical validity. Journal of Clinical and Experimental Neuropsychology, 20 (3), 310-319): the Effort Index (EI; Silverberg, N. D., Wertheimer, J. C., & Fichtenberg, N. L. (2007). An effort index for the repeatable battery for the assessment of neuropsychological status (RBANS). Clinical Neuropsychologist, 21 (5), 841-854) and the Effort Scale (ES; Novitski, J., Steele, S., Karantzoulis, S., & Randolph, C. (2012). The repeatable battery for the assessment of neuropsychological status effort scale. Archives of Clinical Neuropsychology, 27 (2), 190-195). We explored failure rates on these effort measures in a non-litigating mixed dementia sample (N = 145). Failure rate on the EI was high (48%) and associated with dementia severity. In contrast, failure on the ES was 14% but differed based on type of dementia. ES failure was low (4%) when dementia was due to Alzheimer disease (AD), but high (31%) for non-AD dementias. These data raise concerns about use of the RBANS embedded effort measures in dementia evaluations.

  5. Perceived distributed effort in team ball sports.

    PubMed

    Beniscelli, Violeta; Tenenbaum, Gershon; Schinke, Robert Joel; Torregrosa, Miquel

    2014-01-01

    In this study, we explored the multifaceted concept of perceived mental and physical effort in team sport contexts where athletes must invest individual and shared efforts to reach a common goal. Semi-structured interviews were conducted with a convenience sample of 15 Catalan professional coaches (3 women and 12 men, 3 each from the following sports: volleyball, basketball, handball, soccer, and water polo) to gain their views of three perceived effort-related dimensions: physical, psychological, and tactical. From a theoretical thematic analysis, it was found that the perception of effort is closely related to how effort is distributed within the team. Moreover, coaches viewed physical effort in relation to the frequency and intensity of the players' involvement in the game. They identified psychological effort in situations where players pay attention to proper cues, and manage emotions under difficult circumstances. Tactical effort addressed the decision-making process of players and how they fulfilled their roles while taking into account the actions of their teammates and opponents. Based on these findings, a model of perceived distributed effort was developed, which delineates the elements that compose each of the aforementioned dimensions. Implications of perceived distributed effort in team coordination and shared mental models are discussed.

  6. High-performance computing and communications

    SciTech Connect

    Stevens, R.

    1993-11-01

    This presentation has two parts. The first part discusses the US High-Performance Computing and Communications program -- its goals, funding, process, revisions, and research in high-performance computing systems, advanced software technology, and basic research and human resources. The second part of the presentation covers specific work conducted under this program at Argonne National Laboratory. Argonne`s efforts focus on computational science research, software tool development, and evaluation of experimental computer architectures. In addition, the author describes collaborative activities at Argonne in high-performance computing, including an Argonne/IBM project to evaluate and test IBM`s newest parallel computers and the Scalable I/O Initiative being spearheaded by the Concurrent Supercomputing Consortium.

  7. Screening and early detection efforts in lung cancer.

    PubMed

    Kanodra, Neeti M; Silvestri, Gerard A; Tanner, Nichole T

    2015-05-01

    Lung cancer is the leading cause of cancer-related death in the United States. Since publication of results from the National Lung Screening Trial, several professional organizations, including the US Preventive Services Task Force, have published guidelines recommending low-dose computed tomography for screening in asymptomatic, high-risk individuals. The benefits of screening include detection of cancer at an early stage when a definitive cure is possible, but the risks include overdiagnosis, false-positive results, psychological distress, and radiation exposure. The current review covers the scope of low-dose computed tomography screening, potential risks, costs, and future directions in the efforts for early detection of lung cancer.

  8. 1996 Design effort for IFMIF HEBT

    SciTech Connect

    Blind, B.

    1997-01-01

    The paper details the 1996 design effort for the IFMIF HEBT. Following a brief overview, it lists the primary requirements for the beam at the target, describes the design approach and design tools used, introduces the beamline modules, gives the results achieved with the design at this stage, points out possible improvements and gives the names and computer locations of the TRACE3-D and PARMILA files that sum up the design work. The design does not fully meet specifications in regards to the flatness of the distribution at the target. With further work, including if necessary some backup options, the flatness specifications may be realized. It is not proposed that the specifications, namely flatness to {+-}5% and higher-intensity ridges that are no more than 15% above average, be changed at this time. The design also does not meet the requirement that the modules of all beamlines should operate at the same settings. However, the goal of using identical components and operational procedures has been met and only minor returning is needed to produce very similar beam distributions from all beamlines. Significant further work is required in the following areas: TRACE3-D designs and PARMILA runs must be made for the beams coming from accelerators No. 3 and No. 4. Transport of 30-MeV and 35-MeV beams to the targets and beam dump must be studied. Comprehensive error studies must be made. These must result in tolerance specifications and may require design iterations. Detailed interfacing with target-spot instrumentation is required. This instrumentation must be able to check all aspects of the specifications.

  9. Productive and Ineffective Efforts: How Student Effort in High School Mathematics Relates to College Calculus Success

    ERIC Educational Resources Information Center

    Barnett, M.D.; Sonnert, G.; Sadler, P.M.

    2014-01-01

    Relativizing the popular belief that student effort is the key to success, this article finds that effort in the most advanced mathematics course in US high schools is not consistently associated with college calculus performance. We distinguish two types of student effort: productive and ineffective efforts. Whereas the former carries the…

  10. 7 CFR 1944.671 - Equal opportunity requirements and outreach efforts.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 13 2010-01-01 2009-01-01 true Equal opportunity requirements and outreach efforts... § 1944.671 Equal opportunity requirements and outreach efforts. The policies and regulations contained in... addition, the HPG grantee is required to address an outreach effort in their program. The amount...

  11. The influence of music on mental effort and driving performance.

    PubMed

    Ünal, Ayça Berfu; Steg, Linda; Epstude, Kai

    2012-09-01

    The current research examined the influence of loud music on driving performance, and whether mental effort mediated this effect. Participants (N=69) drove in a driving simulator either with or without listening to music. In order to test whether music would have similar effects on driving performance in different situations, we manipulated the simulated traffic environment such that the driving context consisted of both complex and monotonous driving situations. In addition, we systematically kept track of drivers' mental load by making the participants verbally report their mental effort at certain moments while driving. We found that listening to music increased mental effort while driving, irrespective of the driving situation being complex or monotonous, providing support to the general assumption that music can be a distracting auditory stimulus while driving. However, drivers who listened to music performed as well as the drivers who did not listen to music, indicating that music did not impair their driving performance. Importantly, the increases in mental effort while listening to music pointed out that drivers try to regulate their mental effort as a cognitive compensatory strategy to deal with task demands. Interestingly, we observed significant improvements in driving performance in two of the driving situations. It seems like mental effort might mediate the effect of music on driving performance in situations requiring sustained attention. Other process variables, such as arousal and boredom, should also be incorporated to study designs in order to reveal more on the nature of how music affects driving.

  12. Additive synthesis with DIASS-M4C on Argonne National Laboratory`s IBM POWERparallel System (SP)

    SciTech Connect

    Kaper, H.; Ralley, D.; Restrepo, J.; Tiepei, S.

    1995-12-31

    DIASS-M4C, a digital additive instrument was implemented on the Argonne National Laboratory`s IBM POWER parallel System (SP). This paper discusses the need for a massively parallel supercomputer and shows how the code was parallelized. The resulting sounds and the degree of control the user can have justify the effort and the use of such a large computer.

  13. Improving Collaboration by Standardization Efforts in Systems Biology

    PubMed Central

    Dräger, Andreas; Palsson, Bernhard Ø.

    2014-01-01

    Collaborative genome-scale reconstruction endeavors of metabolic networks would not be possible without a common, standardized formal representation of these systems. The ability to precisely define biological building blocks together with their dynamic behavior has even been considered a prerequisite for upcoming synthetic biology approaches. Driven by the requirements of such ambitious research goals, standardization itself has become an active field of research on nearly all levels of granularity in biology. In addition to the originally envisaged exchange of computational models and tool interoperability, new standards have been suggested for an unambiguous graphical display of biological phenomena, to annotate, archive, as well as to rank models, and to describe execution and the outcomes of simulation experiments. The spectrum now even covers the interaction of entire neurons in the brain, three-dimensional motions, and the description of pharmacometric studies. Thereby, the mathematical description of systems and approaches for their (repeated) simulation are clearly separated from each other and also from their graphical representation. Minimum information definitions constitute guidelines and common operation protocols in order to ensure reproducibility of findings and a unified knowledge representation. Central database infrastructures have been established that provide the scientific community with persistent links from model annotations to online resources. A rich variety of open-source software tools thrives for all data formats, often supporting a multitude of programing languages. Regular meetings and workshops of developers and users lead to continuous improvement and ongoing development of these standardization efforts. This article gives a brief overview about the current state of the growing number of operation protocols, mark-up languages, graphical descriptions, and fundamental software support with relevance to systems biology. PMID:25538939

  14. Visual Cues and Listening Effort: Individual Variability

    ERIC Educational Resources Information Center

    Picou, Erin M.; Ricketts, Todd A; Hornsby, Benjamin W. Y.

    2011-01-01

    Purpose: To investigate the effect of visual cues on listening effort as well as whether predictive variables such as working memory capacity (WMC) and lipreading ability affect the magnitude of listening effort. Method: Twenty participants with normal hearing were tested using a paired-associates recall task in 2 conditions (quiet and noise) and…

  15. The Effect of Age on Listening Effort

    ERIC Educational Resources Information Center

    Degeest, Sofie; Keppler, Hannah; Corthals, Paul

    2015-01-01

    Purpose: The objective of this study was to investigate the effect of age on listening effort. Method: A dual-task paradigm was used to evaluate listening effort in different conditions of background noise. Sixty adults ranging in age from 20 to 77 years were included. A primary speech-recognition task and a secondary memory task were performed…

  16. Attention, effort, and fatigue: Neuropsychological perspectives

    NASA Technical Reports Server (NTRS)

    Cohen, Ronald A.; Odonnell, Brian F.

    1988-01-01

    Models of attention, effort, and fatigue are reviewed. Methods are discussed for measuring these phenomena from a neuropsychological and psychophysiological perspective. The following methodologies are included: (1) the autonomic measurement of cognitive effort and quality of encoding; (2) serial assessment approaches to neurophysiological assessment; and (3) the assessment of subjective reports of fatigue using multidimensional ratings and their relationship to neurobehavioral measures.

  17. NASA cryogenic fluid management space experiment efforts

    NASA Technical Reports Server (NTRS)

    Glover, Daniel

    1991-01-01

    A history of technological development for subcritical cryogenic fluid management (CFM) through space experiments is given for the period 1960 to 1990. Space experiments with liquid hydrogen were conducted in the early 1960s. Efforts since then have consisted of studies and designs of potential space experiments. A chronology of CFM space experiments and design efforts is included.

  18. Patterns of Research Effort in Birds

    PubMed Central

    Ducatez, Simon; Lefebvre, Louis

    2014-01-01

    Between species differences in research effort can lead to biases in our global view of evolution, ecology and conservation. The increase in meta-taxonomic comparative analyses on birds underlines the need to better address how research effort is distributed in this class. Methods have been developed to choose which species should be studied to obtain unbiased comparative data sets, but a precise and global knowledge of research effort is required to be able to properly apply them. We address this issue by providing a data set of research effort (number of papers from 1978 to 2008 in the Zoological Record database) estimates for the 10 064 species of birds. We then test whether research effort is associated with phylogeny, geography and eleven different life history and ecological traits. We show that phylogeny accounts for a large proportion of the variance, while geographic range and all the tested traits are also significant contributors to research effort variance. We identify avian taxa that are under- and overstudied and address the importance of research effort biases in evaluating vulnerability to extinction, with non-threatened species studied twice as much as threatened ones. Our research effort data set covering the entire class Aves provides a tool for researchers to incorporate this potential confounding variable in comparative analyses. PMID:24587149

  19. Listening Effort with Cochlear Implant Simulations

    ERIC Educational Resources Information Center

    Pals, Carina; Sarampalis, Anastasios; Baskent, Deniz

    2013-01-01

    Purpose: Fitting a cochlear implant (CI) for optimal speech perception does not necessarily optimize listening effort. This study aimed to show that listening effort may change between CI processing conditions for which speech intelligibility remains constant. Method: Nineteen normal-hearing participants listened to CI simulations with varying…

  20. Negative symptoms are associated with an increased subjective cost of cognitive effort.

    PubMed

    Culbreth, Adam; Westbrook, Andrew; Barch, Deanna

    2016-05-01

    Motivational deficits in schizophrenia are proposed to be attributable in part to abnormal effort-cost computations. Inflated subjective cognitive effort costs may explain diminished functioning in schizophrenia to the extent that they drive avoidance of complex decision-making and planning. Although previous data support inflated subjective physical effort costs for individuals with schizophrenia, evidence on cognitive effort is mixed. We exploited the methodological advantages of a recently developed cognitive effort-discounting paradigm (Westbrook, Kester, & Braver, 2013) to examine effort-cost computations in schizophrenia. The paradigm quantifies subjective costs in terms of explicit, continuous discounting of monetary rewards based on parametrically varied demands (levels N of the N-back working memory task), holding objective features of task duration and reward likelihood constant. Both healthy participants (N = 25) and schizophrenia patients (N = 25) showed systematic influences of reward and task demands on choice patterns. Critically, however, participants with schizophrenia discounted rewards more steeply as a function of effort, indicating that effort was more costly for this group. Moreover, discounting varied robustly with symptomatology, such that schizophrenia patients with greater clinically rated negative symptom severity discounted rewards more steeply. These findings extend the current literature on abnormal-effort cost computations in schizophrenia by establishing a clear relationship between the costliness of cognitive effort and negative symptoms. (PsycINFO Database Record

  1. Information Management System for Site Remediation Efforts.

    PubMed

    Laha; Mukherjee; Nebhrajani

    2000-05-01

    / Environmental regulatory agencies are responsible for protecting human health and the environment in their constituencies. Their responsibilities include the identification, evaluation, and cleanup of contaminated sites. Leaking underground storage tanks (USTs) constitute a major source of subsurface and groundwater contamination. A significant portion of a regulatory body's efforts may be directed toward the management of UST-contaminated sites. In order to manage remedial sites effectively, vast quantities of information must be maintained, including analytical dataon chemical contaminants, remedial design features, and performance details. Currently, most regulatory agencies maintain such information manually. This makes it difficult to manage the data effectively. Some agencies have introduced automated record-keeping systems. However, the ad hoc approach in these endeavors makes it difficult to efficiently analyze, disseminate, and utilize the data. This paper identifies the information requirements for UST-contaminated site management at the Waste Cleanup Section of the Department of Environmental Resources Management in Dade County, Florida. It presents a viable design for an information management system to meet these requirements. The proposed solution is based on a back-end relational database management system with relevant tools for sophisticated data analysis and data mining. The database is designed with all tables in the third normal form to ensure data integrity, flexible access, and efficient query processing. In addition to all standard reports required by the agency, the system provides answers to ad hoc queries that are typically difficult to answer under the existing system. The database also serves as a repository of information for a decision support system to aid engineering design and risk analysis. The system may be integrated with a geographic information system for effective presentation and dissemination of spatial data.

  2. Programming effort analysis of the ELLPACK language

    NASA Technical Reports Server (NTRS)

    Rice, J. R.

    1978-01-01

    ELLPACK is a problem statement language and system for elliptic partial differential equations which is implemented by a FORTRAN preprocessor. ELLPACK's principal purpose is as a tool for the performance evaluation of software. However, it is used here as an example with which to study the programming effort required for problem solving. It is obvious that problem statement languages can reduce programming effort tremendously; the goal is to quantify this somewhat. This is done by analyzing the lengths and effort (as measured by Halstead's software science technique) of various approaches to solving these problems.

  3. Defense Health Care: Additional Efforts Needed to Ensure Compliance with Personality Disorder Separation Requirements

    DTIC Science & Technology

    2008-10-01

    Health Care Page 21 GAO-09-31 DOD Personality Disorder Separations List of Congressional Addressees The Honorable Carl Levin Chairman The...Separations The Honorable Ken Salazar United States Senate The Honorable Bernard Sanders United States Senate Page 23 GAO-09-31 DOD Personality

  4. Report: Additional Efforts Needed to Improve EPA’s Oversight of Assistance Agreements

    EPA Pesticide Factsheets

    Report #2002-P-00018, September 30, 2002. Although EPA developed corrective actions to improve oversight controls for assistance agreements, a number of EPA OIG, Agency, and GAO reviews determined that oversight continued to be a weakness.

  5. VA Disability Benefits: Additional Planning Would Enhance Efforts to Improve the Timeliness of Appeals Decisions

    DTIC Science & Technology

    2017-03-01

    and is not subject to copyright protection in the United States. The published product may be reproduced and distributed in its entirety without...Results Act, GAO/GGD-96-118 (Washington, D.C.: June 1996). 8Simon Blackburn, Sarah Ryerson, Leigh Weiss, Sarah Wilson, and Carter Wood , Insights into...expedite appeals resolutions, it also contains various protections for veterans that are intended to address stakeholders’ concerns about fairness

  6. VA Health Care. Additional Efforts to Better Assess Joint Ventures Needed

    DTIC Science & Technology

    2008-03-01

    Kans. Okla. Minn. Iowa Mo. Ark. La. Ill. Miss. Ind. Ky. Tenn. Ala. Ga. S.C. N.C. Va. Ohio N.H. Mass. Mich . Calif. Wash. Wis. N.Y. Maine Vt. W.Va...train VA personnel in a variety of areas, including basic life support and advanced cardiac life support. Finally, VA officials and academic

  7. Effort-reward imbalance and burnout among nurses.

    PubMed

    Bakker, A B; Killmer, C H; Siegrist, J; Schaufeli, W B

    2000-04-01

    This study among a sample of 204 German nurses tested the hypothesis that an imbalance of high extrinsic efforts spent (i.e. job demands) and low extrinsic rewards obtained (e.g. poor promotion prospects) are associated with the burnout syndrome: the depletion of nurses' emotional resources. The results of a series of analyses of variances confirmed this hypothesis, by showing that those nurses who experienced an effort-reward imbalance (ERI) reported higher levels on two of the three core dimensions of burnout (i.e. emotional exhaustion and depersonalization) than those who did not experience such an imbalance. Moreover - as additionally hypothesized - significant interaction effects indicated that burnout (i.e. emotional exhaustion and reduced personal accomplishment) was particularly prevalent among those nurses who experienced ERI and put relatively high intrinsic effort into their jobs, as reflected by their strong tendency to be personally in control over job conditions.

  8. Future Computer Requirements for Computational Aerodynamics

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Recent advances in computational aerodynamics are discussed as well as motivations for and potential benefits of a National Aerodynamic Simulation Facility having the capability to solve fluid dynamic equations at speeds two to three orders of magnitude faster than presently possible with general computers. Two contracted efforts to define processor architectures for such a facility are summarized.

  9. Savannah River Site computing architecture migration guide

    SciTech Connect

    Not Available

    1991-07-30

    The SRS Computing Architecture is a vision statement for site computing which enumerates the strategies which will guide SRS computing efforts for the 1990s. Each strategy is supported by a number of feature statements which clarify the strategy by providing additional detail. Since it is a strategic planning document, the Architecture has sitewide applicability and endorsement but does not attempt to specify implementation details. It does, however, specify that a document will be developed to guide the migration from the current site environment to that envisioned by the new architecture. The goal of this document, the SRS Computing Architecture Migration Guide, is to identify specific strategic and tactical tasks which would have to be completed to fully implement the architectural vision for site computing as well as a recommended sequence and timeframe for addressing these tasks. It takes into account the expected availability of technology, the existing installed base, and interdependencies among architectural components and objectives.

  10. A specific role for serotonin in overcoming effort cost

    PubMed Central

    Meyniel, Florent; Goodwin, Guy M; Deakin, JF William; Klinge, Corinna; MacFadyen, Christine; Milligan, Holly; Mullings, Emma; Pessiglione, Mathias; Gaillard, Raphaël

    2016-01-01

    Serotonin is implicated in many aspects of behavioral regulation. Theoretical attempts to unify the multiple roles assigned to serotonin proposed that it regulates the impact of costs, such as delay or punishment, on action selection. Here, we show that serotonin also regulates other types of action costs such as effort. We compared behavioral performance in 58 healthy humans treated during 8 weeks with either placebo or the selective serotonin reuptake inhibitor escitalopram. The task involved trading handgrip force production against monetary benefits. Participants in the escitalopram group produced more effort and thereby achieved a higher payoff. Crucially, our computational analysis showed that this effect was underpinned by a specific reduction of effort cost, and not by any change in the weight of monetary incentives. This specific computational effect sheds new light on the physiological role of serotonin in behavioral regulation and on the clinical effect of drugs for depression. Clinical trial Registration: ISRCTN75872983 DOI: http://dx.doi.org/10.7554/eLife.17282.001 PMID:27824554

  11. A metabolic measure of mental effort.

    PubMed

    Fairclough, Stephen H; Houston, Kim

    2004-04-01

    Previous studies have operationalised mental effort via various indices of psychophysiology, particularly cardiovascular measures. Metabolic measures represent a complementary approach wherein mental effort investment is explicitly linked to the process of energy mobilisation. The purpose of this study was to contrast cardiovascular variables (heart rate, 0.1 Hz component of heart rate variability) with a metabolic measure (blood glucose) of mental effort. Twenty-nine participants were exposed to Stroop stimuli over a 45 min period under two conditions: (a) congruent (i.e. 100% congruent Stroop stimuli); and (b) incongruent (i.e. 100% incongruent Stroop stimuli). Performance, blood glucose, cardiovascular activity and subjective mood were measured. The results indicated that blood glucose levels were sensitive to both Stroop and time-on-task variables, whilst cardiovascular measures were only sensitive to the latter. There was also evidence of an association between blood glucose levels and response accuracy. The implications of these findings for the operationalisation of mental effort are discussed.

  12. Council Coordination of Federal Invasive Species Efforts

    DTIC Science & Technology

    2004-08-01

    Chris Dionigi, Assistant Director, Domestic Policy National Invasive Species Council Coordination of Federal Invasive Species Efforts Report...REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE CouncilCoordination of Federal Invasive Species Efforts 5a. CONTRACT NUMBER 5b...ADDRESS(ES) National Invasive Species Council (NISC) 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS

  13. The effects of sleep loss on capacity and effort

    PubMed Central

    Engle-Friedman, Mindy

    2014-01-01

    Sleep loss appears to affect the capacity for performance and access to energetic resources. This paper reviews research examining the physical substrates referred to as resource capacity, the role of sleep in protecting that capacity and the reaction of the system as it attempts to respond with effort to overcome the limitations on capacity caused by sleep loss. Effort is the extent to which an organism will exert itself beyond basic levels of functioning or attempt alternative strategies to maintain performance. The purpose of this review is to bring together research across sleep disciplines to clarify the substrates that constitute and influence capacity for performance, consider how the loss of sleep influences access to those resources, examine cortical, physiological, perceptual, behavioral and subjective effort responses and consider how these responses reflect a system reacting to changes in the resource environment. When sleep deprived, the ability to perform tasks that require additional energy is impaired and the ability of the system to overcome the deficiencies caused by sleep loss is limited. Taking on tasks that require effort including school work, meal preparation, pulling off the road to nap when driving drowsy appear to be more challenging during sleep loss. Sleep loss impacts the effort-related choices we make and those choices may influence our health and safety. PMID:26483932

  14. 1/f noise and effort on implicit measures of bias.

    PubMed

    Correll, Joshua

    2008-01-01

    Phenomena that vary over time can often be represented as a complex waveform. Fourier analysis decomposes this complex wave into a set of sinusoidal component waves. In some phenomena, the amplitude of these waves varies in inverse relation to frequency. This pattern has been called 1/f noise and, unlike white noise, it reflects nonrandom variation. Latencies in simple computer tasks typically reveal 1/f noise, but the magnitude of the noise decreases as tasks become more challenging. The current work hypothesizes a correspondence between 1/f noise and effort, leading to the prediction that increasing effort will reduce 1/f noise. In 2 studies, the author examined the relationship between an individual's attempts to avoid bias (measured in Study 1, manipulated in Study 2) and 1/f noise in implicit measures of stereotyping and prejudice. In each study, participants who made an effort to modulate the use of racial information showed less 1/f noise than did participants who made less effort. The potential value of this analytic approach to social psychology is discussed.

  15. Career Opportunities in Computer Graphics.

    ERIC Educational Resources Information Center

    Langer, Victor

    1983-01-01

    Reviews the impact of computer graphics on industrial productivity. Details the computer graphics technician curriculum at Milwaukee Area Technical College and the cooperative efforts of business and industry to fund and equip the program. (SK)

  16. Children's Sleep and Academic Achievement: The Moderating Role of Effortful Control.

    PubMed

    Diaz, Anjolii; Berger, Rebecca; Valiente, Carlos; Eisenberg, Nancy; VanSchyndel, Sarah; Tao, Chun; Spinrad, Tracy L; Doane, Leah D; Thompson, Marilyn S; Silva, Kassondra M; Southworth, Jody

    2017-03-01

    Poor sleep is thought to interfere with children's learning and academic achievement (AA). However, existing research and theory indicate there are factors that may mitigate the academic risk associated with poor sleep. The purpose of this study was to examine the moderating role of children's effortful control (EC) on the relation between sleep and AA in young children. One hundred and three 4.5- to 7-year-olds (M = 5.98 years, SD = 0.61) wore a wrist-based actigraph for five continuous weekday nights. Teachers and coders reported on children's EC. EC was also assessed with a computer-based task at school. Additionally, we obtained a standardized measure of children's AA. There was a positive main effect of sleep efficiency to AA. Several relations between sleep and AA were moderated by EC and examination of the simple slopes indicated that the negative relation between sleep and AA was only significant at low levels of EC.

  17. Defining Computational Thinking for Mathematics and Science Classrooms

    NASA Astrophysics Data System (ADS)

    Weintrop, David; Beheshti, Elham; Horn, Michael; Orton, Kai; Jona, Kemi; Trouille, Laura; Wilensky, Uri

    2016-02-01

    Science and mathematics are becoming computational endeavors. This fact is reflected in the recently released Next Generation Science Standards and the decision to include "computational thinking" as a core scientific practice. With this addition, and the increased presence of computation in mathematics and scientific contexts, a new urgency has come to the challenge of defining computational thinking and providing a theoretical grounding for what form it should take in school science and mathematics classrooms. This paper presents a response to this challenge by proposing a definition of computational thinking for mathematics and science in the form of a taxonomy consisting of four main categories: data practices, modeling and simulation practices, computational problem solving practices, and systems thinking practices. In formulating this taxonomy, we draw on the existing computational thinking literature, interviews with mathematicians and scientists, and exemplary computational thinking instructional materials. This work was undertaken as part of a larger effort to infuse computational thinking into high school science and mathematics curricular materials. In this paper, we argue for the approach of embedding computational thinking in mathematics and science contexts, present the taxonomy, and discuss how we envision the taxonomy being used to bring current educational efforts in line with the increasingly computational nature of modern science and mathematics.

  18. Technology for Kids' Desktops: How One School Brought Its Computers Out of the Lab and into Classrooms.

    ERIC Educational Resources Information Center

    Bozzone, Meg A.

    1997-01-01

    Purchasing custom-made desks with durable glass tops to house computers and double as student work space solved the problem of how to squeeze in additional classroom computers at Johnson Park Elementary School in Princeton, New Jersey. This article describes a K-5 grade school's efforts to overcome barriers to integrating technology. (PEN)

  19. Vocal effort and voice handicap among teachers.

    PubMed

    Sampaio, Márcio Cardoso; dos Reis, Eduardo José Farias Borges; Carvalho, Fernando Martins; Porto, Lauro Antonio; Araújo, Tânia Maria

    2012-11-01

    The relationship between voice handicap and professional vocal effort was investigated among teachers in a cross-sectional study of census nature on 4496 teachers within the public elementary education network in Salvador, Bahia, Brazil. Voice handicap (the outcome of interest) was evaluated using the Voice Handicap Index 10. The main exposure, the lifetime vocal effort index, was obtained as the product of the number of years working as a teacher multiplied by the mean weekly working hours. The prevalence of voice handicap was 28.8% among teachers with high professional vocal effort and 21.3% among those with acceptable vocal effort, thus yielding a crude prevalence ratio (PR) of 1.36 (95% confidence interval [CI]=1.14-1.61). In the final logistic model, the prevalence of voice handicap was statistically associated with the professional vocal effort index (PR=1.47; 95% CI=1.19-1.82), adjusted according to sex, microphone availability in the classroom, excessive noise, pressure from the school management, heartburn, and rhinitis.

  20. Teardrop bladder: additional considerations

    SciTech Connect

    Wechsler, R.J.; Brennan, R.E.

    1982-07-01

    Nine cases of teardrop bladder (TDB) seen at excretory urography are presented. In some of these patients, the iliopsoas muscles were at the upper limit of normal in size, and additional evaluation of the perivesical structures with computed tomography (CT) was necessary. CT demonstrated only hypertrophied muscles with or without perivesical fat. The psoas muscles and pelvic width were measured in 8 patients and compared with the measurements of a control group of males without TDB. Patients with TDB had large iliopsoas muscles and narrow pelves compared with the control group. The psoas muscle width/pelvic width ratio was significantly greater (p < 0.0005) in patients with TDB than in the control group, with values of 1.04 + 0.05 and 0.82 + 0.09, respectively. It is concluded that TDB is not an uncommon normal variant in black males. Both iliopsoas muscle hypertrophy and a narrow pelvis are factors that predispose a patient to TDB.

  1. The role of cognitive effort in subjective reward devaluation and risky decision-making

    PubMed Central

    Apps, Matthew A J; Grima, Laura L; Manohar, Sanjay; Husain, Masud

    2015-01-01

    Motivation is underpinned by cost-benefit valuations where costs—such as physical effort or outcome risk—are subjectively weighed against available rewards. However, in many environments risks pertain not to the variance of outcomes, but to variance in the possible levels of effort required to obtain rewards (effort risks). Moreover, motivation is often guided by the extent to which cognitive—not physical—effort devalues rewards (effort discounting). Yet, very little is known about the mechanisms that underpin the influence of cognitive effort risks or discounting on motivation. We used two cost-benefit decision-making tasks to probe subjective sensitivity to cognitive effort (number of shifts of spatial attention) and to effort risks. Our results show that shifts of spatial attention when monitoring rapidly presented visual stimuli are perceived as effortful and devalue rewards. Additionally, most people are risk-averse, preferring safe, known amounts of effort over risky offers. However, there was no correlation between their effort and risk sensitivity. We show for the first time that people are averse to variance in the possible amount of cognitive effort to be exerted. These results suggest that cognitive effort sensitivity and risk sensitivity are underpinned by distinct psychological and neurobiological mechanisms. PMID:26586084

  2. The role of cognitive effort in subjective reward devaluation and risky decision-making.

    PubMed

    Apps, Matthew A J; Grima, Laura L; Manohar, Sanjay; Husain, Masud

    2015-11-20

    Motivation is underpinned by cost-benefit valuations where costs-such as physical effort or outcome risk-are subjectively weighed against available rewards. However, in many environments risks pertain not to the variance of outcomes, but to variance in the possible levels of effort required to obtain rewards (effort risks). Moreover, motivation is often guided by the extent to which cognitive-not physical-effort devalues rewards (effort discounting). Yet, very little is known about the mechanisms that underpin the influence of cognitive effort risks or discounting on motivation. We used two cost-benefit decision-making tasks to probe subjective sensitivity to cognitive effort (number of shifts of spatial attention) and to effort risks. Our results show that shifts of spatial attention when monitoring rapidly presented visual stimuli are perceived as effortful and devalue rewards. Additionally, most people are risk-averse, preferring safe, known amounts of effort over risky offers. However, there was no correlation between their effort and risk sensitivity. We show for the first time that people are averse to variance in the possible amount of cognitive effort to be exerted. These results suggest that cognitive effort sensitivity and risk sensitivity are underpinned by distinct psychological and neurobiological mechanisms.

  3. An Overview of the Launch Vehicle Blast Environments Development Efforts

    NASA Technical Reports Server (NTRS)

    Richardson, Erin; Bangham, Mike; Blackwood, James; Skinner, Troy; Hays, Michael; Jackson, Austin; Richman, Ben

    2014-01-01

    NASA has been funding an ongoing development program to characterize the explosive environments produced during a catastrophic launch vehicle accident. These studies and small-scale tests are focused on the near field environments that threaten the crew. The results indicate that these environments are unlikely to result in immediate destruction of the crew modules. The effort began as an independent assessment by NASA safety organizations, followed by the Ares program and NASA Engineering and Safety Center and now as a Space Launch Systems (SLS) focused effort. The development effort is using the test and accident data available from public or NASA sources as well as focused scaled tests that are examining the fundamental aspects of uncontained explosions of Hydrogen and air and Hydrogen and Oxygen. The primary risk to the crew appears to be the high-energy fragments and these are being characterized for the SLS. The development efforts will characterize the thermal environment of the explosions as well to ensure that the risk is well understood and to document the overall energy balance of an explosion. The effort is multi-path in that analytical, computational and focused testing is being used to develop the knowledge to understand potential SLS explosions. This is an ongoing program with plans that expand the development from fundamental testing at small-scale levels to large-scale tests that can be used to validate models for commercial programs. The ultimate goal is to develop a knowledge base that can be used by vehicle designers to maximize crew survival in an explosion.

  4. Update on research software citation efforts

    NASA Astrophysics Data System (ADS)

    Allen, Alice

    2017-01-01

    Research software citation has received a lot of attention the past few years, as evidenced by numerous efforts that have discussed it, including WSSSPE, Force11 Software Citation Working Group, the Center for Open Science's Transparency and Openness Promotion (TOP) Guidelines, a workshop on Engineering Academic Software, and the CodeMeta project. This presentation briefly covers recent broad efforts to improve research transparency across disciplines through software availability and citation, and the Software Citation Principles that have recently been published as a result of the work done through Force11.

  5. Least-effort trajectories lead to emergent crowd behaviors.

    PubMed

    Guy, Stephen J; Curtis, Sean; Lin, Ming C; Manocha, Dinesh

    2012-01-01

    Pedestrian crowds often have been modeled as many-particle systems, usually using computer models known as multiagent simulations. The key challenge in modeling crowds is to develop rules that guide how the particles or agents interact with each other in a way that faithfully reproduces paths and behaviors commonly seen in real human crowds. Here, we propose a simple and intuitive formulation of these rules based on biomechanical measurements and the principle of least effort. We present a constrained optimization method to compute collision-free paths of minimum caloric energy for each agent, from which collective crowd behaviors can be reproduced. We show that our method reproduces common crowd phenomena, such as arching and self-organization into lanes. We also validate the flow rates and paths produced by our method and compare them to those of real-world crowd trajectories.

  6. Making life easier with effort: Basic findings and applied research on response effort

    PubMed Central

    Friman, Patrick C.; Poling, Alan

    1995-01-01

    Early basic research showed that increases in required response effort (or force) produced effects that resembled those produced by punishment. A recent study by Alling and Poling determined some subtle differences between the two behavior-change strategies, but also confirmed that increasing required effort is an effective response-reduction procedure with enduring effects. In this paper we summarize basic research on response effort and explore the role of effort in diverse applied areas including deceleration of aberrant behavior, attention deficit hyperactivity disorder, oral habits, health care appointment keeping, littering, indexes of functional disability, and problem solving. We conclude that renewed interest in response effort as an independent variable is justified because of its potent effects and because the political constraints imposed on punishment- and reinforcement-based procedures have yet to be imposed on procedures that entail manipulations of response effort. PMID:16795886

  7. Making life easier with effort: Basic findings and applied research on response effort.

    PubMed

    Friman, P C

    1995-01-01

    Early basic research showed that increases in required response effort (or force) produced effects that resembled those produced by punishment. A recent study by Alling and Poling determined some subtle differences between the two behavior-change strategies, but also confirmed that increasing required effort is an effective response-reduction procedure with enduring effects. In this paper we summarize basic research on response effort and explore the role of effort in diverse applied areas including deceleration of aberrant behavior, attention deficit hyperactivity disorder, oral habits, health care appointment keeping, littering, indexes of functional disability, and problem solving. We conclude that renewed interest in response effort as an independent variable is justified because of its potent effects and because the political constraints imposed on punishment- and reinforcement-based procedures have yet to be imposed on procedures that entail manipulations of response effort.

  8. Statistical Modeling Efforts for Headspace Gas

    SciTech Connect

    Weaver, Brian Phillip

    2016-03-17

    The purpose of this document is to describe the statistical modeling effort for gas concentrations in WIPP storage containers. The concentration (in ppm) of CO2 in the headspace volume of standard waste box (SWB) 68685 is shown. A Bayesian approach and an adaptive Metropolis-Hastings algorithm were used.

  9. Instruction Emphasizing Effort Improves Physics Problem Solving

    ERIC Educational Resources Information Center

    Li, Daoquan

    2012-01-01

    Effectively using strategies to solve complex problems is an important educational goal and is implicated in successful academic performance. However, people often do not spontaneously use the effective strategies unless they are motivated to do so. The present study was designed to test whether educating students about the importance of effort in…

  10. Mental Effort in Mobility Route Learning

    ERIC Educational Resources Information Center

    Martinsen, Harald; Tellevik, Jon Magne; Elmerskog, Bengt; Storlilokken, Magnar

    2007-01-01

    This study examined the mental effort required to monitor landmarks and the effect of the type of route on mobility-route training. The results revealed that the features of landmarks and competence in travel were significantly related, indicating that some environmental factors related to height and width are more easily learned when people can…

  11. Revolutionary Educational Reform Efforts in Latin America.

    ERIC Educational Resources Information Center

    Paulston, Rolland G.

    1975-01-01

    The author briefly examines how educational reform attempts in Cuba since 1959 have taken place and how they have been related to social, economic, and political change efforts in the society at large. The Cuban educational system makes a significant contrast against the failure which characterizes the other Latin American educational systems.…

  12. School Trips: Are They Worth the Effort?

    ERIC Educational Resources Information Center

    Johnston, Robert

    2015-01-01

    Even the most basic of school trips will require booking places, arranging transport, writing to parents, collecting payments, planning activities, producing worksheets and, of course, endless risk assessments. It always leaves teachers wondering: "is it really worth all this effort?" Robert Johnston believes that every teacher should…

  13. Philanthropies Add Weight to "i3" Effort

    ERIC Educational Resources Information Center

    Robelen, Erik W.; McNeil, Michele

    2010-01-01

    The author reports on a new effort by 12 major education philanthropies that aims to dovetail with the Education Department's "i3" agenda, raising complex issues. The decision by a dozen major education grantmakers to team up on an initiative designed to dovetail with the federal "Investing in Innovation" grant competition is being seen by…

  14. Report: hospitals need more sophisticated planning efforts.

    PubMed

    Anderson, H J

    1990-09-20

    Sophisticated planning efforts are increasing among hospitals. However, hospital planners and marketers still have far to go before they can match their counterparts in industry. This is according to a report on hospital planning recently released by the Society for Healthcare Planning and Marketing of the American Hospital Association, Chicago.

  15. Testosterone and reproductive effort in male primates.

    PubMed

    Muller, Martin N

    2016-09-08

    Considerable evidence suggests that the steroid hormone testosterone mediates major life-history trade-offs in vertebrates, promoting mating effort at the expense of parenting effort or survival. Observations from a range of wild primates support the "Challenge Hypothesis," which posits that variation in male testosterone is more closely associated with aggressive mating competition than with reproductive physiology. In both seasonally and non-seasonally breeding species, males increase testosterone production primarily when competing for fecund females. In species where males compete to maintain long-term access to females, testosterone increases when males are threatened with losing access to females, rather than during mating periods. And when male status is linked to mating success, and dependent on aggression, high-ranking males normally maintain higher testosterone levels than subordinates, particularly when dominance hierarchies are unstable. Trade-offs between parenting effort and mating effort appear to be weak in most primates, because direct investment in the form of infant transport and provisioning is rare. Instead, infant protection is the primary form of paternal investment in the order. Testosterone does not inhibit this form of investment, which relies on male aggression. Testosterone has a wide range of effects in primates that plausibly function to support male competitive behavior. These include psychological effects related to dominance striving, analgesic effects, and effects on the development and maintenance of the armaments and adornments that males employ in mating competition.

  16. Economic Woes May Hurt Colleges' Green Efforts

    ERIC Educational Resources Information Center

    Carlson, Scott

    2008-01-01

    Recent events on Wall Street raise a complicated question: Will the financial crisis help or hurt colleges' sustainability efforts? Both are possible. In this article, the author discusses how the Wall Street meltdown may hurt colleges' green initiatives. However, advocates of sustainability see an opportunity to change the conversation. A…

  17. ESA NEOCC effort to eliminate high Palermo Scale virtual impactors

    NASA Astrophysics Data System (ADS)

    Micheli, M.; Koschny, D.; Hainaut, O.; Bernardi, F.

    2014-07-01

    At the moment of this writing about 4 % of the known near-Earth objects are known to have at least one future close approach scenario with a non-negligible collision probability within the next century, as routinely computed by the NEODyS and Sentry systems. The most straightforward way to improve the knowledge of the future dynamics of an NEO in order to exclude (or possibly confirm) some of these possible future impact is to obtain additional astrometric observations of the object as soon as it becomes observable again. In particular, since a large fraction (>98 %) of the known objects currently recognized as possible future impactors have been observed during a single opposition, this usually corresponds to obtaining a new set of observations during a second opposition, a so called ''recovery''. However, in some cases the future observability windows for the target after the discovery apparition may be very limited, either because the object is intrinsically small (and therefore requires a very close and consequently rare approach to become observable) or because its orbital dynamic prevents the observability from the ground for a long timespan (as in the case of quasi-resonant objects with a long synodic period). When this happens, the only short-term way to clarify an impact scenario is to look toward the past, and investigate the possibility that unrecognized detections of the object are already present in the databases of old astronomical images, which are often archived by professional telescopes and made available to the community a few months to years after they are exposed. We will here present an effort lead by the newly formed ESA NEO Coordination Centre (NEOCC) in Frascati to pursue both these avenues with the intent of improving the orbital knowledge of the highest-rated possible impactors, as defined by the Palermo Technical Impact Hazard Scale (PS in the following). As an example of our ongoing observational activities, we will first present our

  18. The road to heaven is paved with effort: Perceived effort amplifies moral judgment.

    PubMed

    Bigman, Yochanan E; Tamir, Maya

    2016-12-01

    If good intentions pave the road to hell, what paves the road to heaven? We propose that moral judgments are based, in part, on the degree of effort exerted in performing the immoral or moral act. Because effort can serve as an index of goal importance, greater effort in performing immoral acts would lead to more negative judgments, whereas greater effort in performing moral acts would lead to more positive judgments. In support of these ideas, we found that perceived effort intensified judgments of both immoral (Studies 1-2) and moral (Studies 2-7) agents. The effect of effort on judgment was independent of the outcome (Study 3) and of perceptions of the outcome extremity (Study 6). Furthermore, the effect of effort on judgment was mediated by perceived goal importance (Studies 4-6), even when controlling for perceived intentions (Studies 5-6). Finally, we demonstrate that perceived effort can influence actual behavior, such as the assignment of monetary rewards (Study 7). We discuss the possible implications of effort as a causal motivational factor in moral judgment and social retribution. (PsycINFO Database Record

  19. Aerodynamic optimization studies on advanced architecture computers

    NASA Technical Reports Server (NTRS)

    Chawla, Kalpana

    1995-01-01

    The approach to carrying out multi-discipline aerospace design studies in the future, especially in massively parallel computing environments, comprises of choosing (1) suitable solvers to compute solutions to equations characterizing a discipline, and (2) efficient optimization methods. In addition, for aerodynamic optimization problems, (3) smart methodologies must be selected to modify the surface shape. In this research effort, a 'direct' optimization method is implemented on the Cray C-90 to improve aerodynamic design. It is coupled with an existing implicit Navier-Stokes solver, OVERFLOW, to compute flow solutions. The optimization method is chosen such that it can accomodate multi-discipline optimization in future computations. In the work , however, only single discipline aerodynamic optimization will be included.

  20. Computer Augmented Video Education.

    ERIC Educational Resources Information Center

    Sousa, M. B.

    1979-01-01

    Describes project CAVE (Computer Augmented Video Education), an ongoing effort at the U.S. Naval Academy to present lecture material on videocassette tape, reinforced by drill and practice through an interactive computer system supported by a 12 channel closed circuit television distribution and production facility. (RAO)

  1. Making Life Easier with Effort: Basic Findings and Applied Research on Response Effort.

    ERIC Educational Resources Information Center

    Friman, Patrick C.; Poling, Alan

    1995-01-01

    This paper summarizes basic research on response effort in diverse applied areas including deceleration of aberrant behavior, attention deficit-hyperactivity disorder, oral habits, littering, and problem solving. The paper concludes that response effort as an independent variable has potent effects, and research exploring the applied benefits of…

  2. ATR NATIONAL SCIENTIFIC USER FACILITY INSTRUMENTATION ENHANCEMENT EFFORTS

    SciTech Connect

    Joy L. Rempe; Mitchell K. Meyer

    2009-04-01

    A key component of the Advanced Test Reactor (ATR) National Scientific User Facility (NSUF) effort is to enhance instrumentation techniques available to users conducting irradiation tests in this unique facility. In particular, development of sensors capable of providing ‘real-time’ measurements of key irradiation parameters is emphasized because of their potential to offer increased fidelity data and reduced post-test examination costs. This paper describes the strategy for identifying new instrumentation needed for ATR irradiations and the program underway to develop and evaluate new sensors to address these needs. Accomplishments from this program are illustrated by describing several new sensors now available to users of the ATR NSUF. In addition, progress is reported on current research efforts to provide users improved in-pile instrumentation.

  3. Repeated-sprint and effort ability in rugby league players.

    PubMed

    Johnston, Rich D; Gabbett, Tim J

    2011-10-01

    The aim of this study was to (a) investigate the influence of tackling on repeated-sprint performance; (b) determine whether repeated-sprint ability (RSA) and repeated-effort ability (REA) are 2 distinct qualities; and (c) assess the test-retest reliability of repeated-sprint and repeated-effort tests in rugby league. Twelve rugby league players performed a repeated-sprint (12 × 20-m sprints performed on a 20-second cycle) and a repeated-effort (12 × 20-m sprints with intermittent tackling, performed on a 20-second cycle) test 7 days apart. The test-retest reliability of these tests was also established. Heart rate and rating of perceived exertion were recorded throughout the tests. There was a significantly greater (p ≤ 0.05) and large effect size (ES) differences for total sprint time (ES = 1.19), average heart rate (ES = 1.64), peak heart rate (ES = 1.35), and perceived exertion (ES = 3.39) for the repeated-effort test compared with the repeated-sprint test. A large difference (ES = 1.02, p = 0.06) was detected for percentage decrement between the 2 tests. No significant relationship was found between the repeated-sprint and repeated-effort tests for any of the dependent variables. Both tests proved reliable, with total sprint time being the most reliable method of assessing performance. This study demonstrates that the addition of tackling significantly increases the physiological response to repeated-sprint exercise and reduces repeated-sprint performance in rugby league players. Furthermore, RSA and REA appear to be 2 distinct qualities that can be reliably assessed with total time being the most reliable measure of performance.

  4. Heart rate variability related to effort at work.

    PubMed

    Uusitalo, Arja; Mets, Terhi; Martinmäki, Kaisu; Mauno, Saija; Kinnunen, Ulla; Rusko, Heikki

    2011-11-01

    Changes in autonomic nervous system function have been related to work stress induced increases in cardiovascular morbidity and mortality. Our purpose was to examine whether various heart rate variability (HRV) measures and new HRV-based relaxation measures are related to self-reported chronic work stress and daily emotions. The relaxation measures are based on neural network modelling of individual baseline heart rate and HRV information. Nineteen healthy hospital workers were studied during two work days during the same work period. Daytime, work time and night time heart rate, as well as physical activity were recorded. An effort-reward imbalance (ERI) questionnaire was used to assess chronic work stress. The emotions of stress, irritation and satisfaction were assessed six times during both days. Seventeen subjects had an ERI ratio over 1, indicating imbalance between effort and reward, that is, chronic work stress. Of the daily emotions, satisfaction was the predominant emotion. The daytime relaxation percentage was higher on Day 2 than on Day 1 (4 ± 6% vs. 2 ± 3%, p < 0.05) and the night time relaxation (43 ± 30%) was significantly higher than daytime or work time relaxation on the both Days. Chronic work stress correlated with the vagal activity index of HRV. However, effort at work had many HRV correlates: the higher the work effort the lower daytime HRV and relaxation time. Emotions at work were also correlated with work time (stress and satisfaction) and night time (irritation) HRV. These results indicate that daily emotions at work and chronic work stress, especially effort, is associated with cardiac autonomic function. Neural network modelling of individual heart rate and HRV information may provide additional information in stress research in field conditions.

  5. New technology emphasizes international offshore effort

    SciTech Connect

    1997-07-01

    While the offshore industry is focusing its major development efforts on the deeper waters of the US Gulf, West Africa and Brazil, technology has not stood still in the world`s many other established and frontier offshore development areas. These selected items drawn from contributions by UK companies and a major joint-venture development in Eastern Canada emphasize this effort. Included here are: (1) announcement of a major six-field, 3 Tcf gas development off Nova Scotia`s Sable Island and award of two drilling contracts; (2) a comprehensive study of mobile production units in the UK by Smith Rea Energy Analysts; (3) four applications of an option to high-pressure swivels on an FPSO with multiple subsea inlet lines; (4) a contract to supply a DC bus drive for 17 ESPs on Texaco`s Captain field; and (5) review of an environmental study of the Falkland Islands in preparation for exploration activity.

  6. Does software design complexity affect maintenance effort?

    NASA Technical Reports Server (NTRS)

    Epping, Andreas; Lott, Christopher M.

    1994-01-01

    The design complexity of a software system may be characterized within a refinement level (e.g., data flow among modules), or between refinement levels (e.g., traceability between the specification and the design). We analyzed an existing set of data from NASA's Software Engineering Laboratory to test whether changing software modules with high design complexity requires more personnel effort than changing modules with low design complexity. By analyzing variables singly, we identified strong correlations between software design complexity and change effort for error corrections performed during the maintenance phase. By analyzing variables in combination, we found patterns which identify modules in which error corrections were costly to perform during the acceptance test phase.

  7. Final Report on the NCAR VTMX Effort

    SciTech Connect

    Parsons, David; Pinto, James; Brown, William; Cohen, Stephen; Morley, Bruce

    2007-02-13

    The NCAR effort is primarily focused on the analysis of a diverse suite of measurements taken at the southern end of the Salt Lake City Valley within the Jordan Narrows. These measurements include wind profiler, surface, lidar, radiosonde, multi-layered tether-sonde and sodar measurements. We are also collaborating with other VTMX investigators through linking our measurements within the Jordan Narrows with their investigations. The instrumentation was provided to interested VTMX investigators and was used extensively. Thus the NCAR data set played a large role in the results of the overall experiment. Our work under this proposal includes analysis of the observations, mesoscale modeling efforts in support of our VTMX analysis and general instrumentation development aimed at improving the measurement of vertical transport and mixing under stable conditions. This report is subdivided by research objectives.

  8. Combining "real effort" with induced effort costs: the ball-catching task.

    PubMed

    Gächter, Simon; Huang, Lingbo; Sefton, Martin

    2016-01-01

    We introduce the "ball-catching task", a novel computerized task, which combines a tangible action ("catching balls") with induced material cost of effort. The central feature of the ball-catching task is that it allows researchers to manipulate the cost of effort function as well as the production function, which permits quantitative predictions on effort provision. In an experiment with piece-rate incentives we find that the comparative static and the point predictions on effort provision are remarkably accurate. We also present experimental findings from three classic experiments, namely, team production, gift exchange and tournament, using the task. All of the results are closely in line with the stylized facts from experiments using purely induced values. We conclude that the ball-catching task combines the advantages of real effort tasks with the use of induced values, which is useful for theory-testing purposes as well as for applications.

  9. Development and application of computational aerothermodynamics flowfield computer codes

    NASA Technical Reports Server (NTRS)

    Venkatapathy, Ethiraj

    1994-01-01

    Research was performed in the area of computational modeling and application of hypersonic, high-enthalpy, thermo-chemical nonequilibrium flow (Aerothermodynamics) problems. A number of computational fluid dynamic (CFD) codes were developed and applied to simulate high altitude rocket-plume, the Aeroassist Flight Experiment (AFE), hypersonic base flow for planetary probes, the single expansion ramp model (SERN) connected with the National Aerospace Plane, hypersonic drag devices, hypersonic ramp flows, ballistic range models, shock tunnel facility nozzles, transient and steady flows in the shock tunnel facility, arc-jet flows, thermochemical nonequilibrium flows around simple and complex bodies, axisymmetric ionized flows of interest to re-entry, unsteady shock induced combustion phenomena, high enthalpy pulsed facility simulations, and unsteady shock boundary layer interactions in shock tunnels. Computational modeling involved developing appropriate numerical schemes for the flows on interest and developing, applying, and validating appropriate thermochemical processes. As part of improving the accuracy of the numerical predictions, adaptive grid algorithms were explored, and a user-friendly, self-adaptive code (SAGE) was developed. Aerothermodynamic flows of interest included energy transfer due to strong radiation, and a significant level of effort was spent in developing computational codes for calculating radiation and radiation modeling. In addition, computational tools were developed and applied to predict the radiative heat flux and spectra that reach the model surface.

  10. Counternarcotic Efforts in the Southern Cone: Argentina

    DTIC Science & Technology

    1990-06-15

    in supporting international counter- narcotic actions. The epilogue stresses the need to change some aspects of the U.S. life-style to avoid losing the...Argentina is giving its best effort in supporting international countornarcotic actions. The epilogue in Chapter IV, stresses the need to change sono...International Narcotics Convention of 1961 which calls for the prohibition on coca chewing, but did not change its policy concerning the implemontation

  11. NRC; Smog control efforts off mark

    SciTech Connect

    Not Available

    1992-01-06

    This paper reports that the National Research Council says the U.S. regulatory programs to control smog may have been misdirected the past 20 years, and more emphasis needs to be placed on limiting nitrogen oxide emissions. An NRC study the ozone control efforts have focused mainly on controlling volatile organic compounds (VOC) emissions. However, in many parts of the country controlling emissions of nitrogen oxides would be more effective, it the, noting VOCs and nitrogen oxides are precursors of ozone.

  12. Assessing Post Conflict State Building Efforts

    DTIC Science & Technology

    2013-03-01

    economic growth, and democratization). Success does not just depend on inputs but also in how the resources are employed and the susceptibility of the...broader effort to promote political and economic reforms with the objective of transforming a society emerging from conflict into one at peace with...establishing public security and the rule of law, facilitating political transition, rebuilding infrastructure, and jumpstarting economic recovery. These

  13. Joint SatOPS Compatibility Efforts

    NASA Technical Reports Server (NTRS)

    Smith, Danford

    2010-01-01

    This slide presentation reviews NASA Goddard Space Flight Center's (GSFC) participation in the interagency cooperation committee, the Joint SatOps Compatibility Committee (JSCC), and the compatible Sat 2 efforts. Part of GSFC's participation in the JSCC is to work with the Goddard Mission Systems Evolution Center (GMSEC) to provides a publish/subscribe framework to enable rapid integration of commercially available satellite control products.

  14. Qualitative Evaluation of Health Information Exchange Efforts

    PubMed Central

    Ash, Joan S.; Guappone, Kenneth P.

    2007-01-01

    Because most health information exchange (HIE) initiatives are as yet immature, formative evaluation is recommended so that what is learned through evaluation can be immediately applied to assist in HIE development efforts. Qualitative methods can be especially useful for formative evaluation because they can guide ongoing HIE growth while taking context into consideration. This paper describes important HIE-related research questions and outlines appropriate qualitative research techniques for addressing them. PMID:17904914

  15. Computational Combustion

    SciTech Connect

    Westbrook, C K; Mizobuchi, Y; Poinsot, T J; Smith, P J; Warnatz, J

    2004-08-26

    Progress in the field of computational combustion over the past 50 years is reviewed. Particular attention is given to those classes of models that are common to most system modeling efforts, including fluid dynamics, chemical kinetics, liquid sprays, and turbulent flame models. The developments in combustion modeling are placed into the time-dependent context of the accompanying exponential growth in computer capabilities and Moore's Law. Superimposed on this steady growth, the occasional sudden advances in modeling capabilities are identified and their impacts are discussed. Integration of submodels into system models for spark ignition, diesel and homogeneous charge, compression ignition engines, surface and catalytic combustion, pulse combustion, and detonations are described. Finally, the current state of combustion modeling is illustrated by descriptions of a very large jet lifted 3D turbulent hydrogen flame with direct numerical simulation and 3D large eddy simulations of practical gas burner combustion devices.

  16. Overview of Materials Qualification Needs for Metal Additive Manufacturing

    NASA Astrophysics Data System (ADS)

    Seifi, Mohsen; Salem, Ayman; Beuth, Jack; Harrysson, Ola; Lewandowski, John J.

    2016-03-01

    This overview highlights some of the key aspects regarding materials qualification needs across the additive manufacturing (AM) spectrum. AM technology has experienced considerable publicity and growth in the past few years with many successful insertions for non-mission-critical applications. However, to meet the full potential that AM has to offer, especially for flight-critical components (e.g., rotating parts, fracture-critical parts, etc.), qualification and certification efforts are necessary. While development of qualification standards will address some of these needs, this overview outlines some of the other key areas that will need to be considered in the qualification path, including various process-, microstructure-, and fracture-modeling activities in addition to integrating these with lifing activities targeting specific components. Ongoing work in the Advanced Manufacturing and Mechanical Reliability Center at Case Western Reserve University is focusing on fracture and fatigue testing to rapidly assess critical mechanical properties of some titanium alloys before and after post-processing, in addition to conducting nondestructive testing/evaluation using micro-computerized tomography at General Electric. Process mapping studies are being conducted at Carnegie Mellon University while large area microstructure characterization and informatics (EBSD and BSE) analyses are being conducted at Materials Resources LLC to enable future integration of these efforts via an Integrated Computational Materials Engineering approach to AM. Possible future pathways for materials qualification are provided.

  17. Computer Literacy in a First-Year Medical School Class

    PubMed Central

    Magid, Alan D.; Rabold, Jean S.; Stead, William W.

    1988-01-01

    Students entering Duke Medical School in August, 1987 were introduced to several computer-related activities within the context of the Medical Physiology course as part of the Medical Center's effort to test a model for achieving an Integrated Academic Information Management System (IAIMS). A questionnaire was administered that sought to measure the extent of prior computer experience, the perceived impact of two physiological computer simulation laboratories, and the desired content of future computer training. The survey showed that 85% had some prior experience: for example, 50% had studied programming, 79% have used word-processing software, 24% own a personal computer, and an additional 25% had access to one. Many students expressed the desire for further training in standard applications and in simulation programs. After lab, about 40% reported improved physiologic understanding but no objective effect of the computer laboratories on exam performance was found.

  18. The human subthalamic nucleus encodes the subjective value of reward and the cost of effort during decision-making

    PubMed Central

    Zénon, Alexandre; Duclos, Yann; Carron, Romain; Witjas, Tatiana; Baunez, Christelle; Régis, Jean; Azulay, Jean-Philippe; Brown, Peter; Eusebio, Alexandre

    2016-01-01

    Adaptive behaviour entails the capacity to select actions as a function of their energy cost and expected value and the disruption of this faculty is now viewed as a possible cause of the symptoms of Parkinson’s disease. Indirect evidence points to the involvement of the subthalamic nucleus—the most common target for deep brain stimulation in Parkinson’s disease—in cost-benefit computation. However, this putative function appears at odds with the current view that the subthalamic nucleus is important for adjusting behaviour to conflict. Here we tested these contrasting hypotheses by recording the neuronal activity of the subthalamic nucleus of patients with Parkinson’s disease during an effort-based decision task. Local field potentials were recorded from the subthalamic nucleus of 12 patients with advanced Parkinson’s disease (mean age 63.8 years ± 6.8; mean disease duration 9.4 years ± 2.5) both OFF and ON levodopa while they had to decide whether to engage in an effort task based on the level of effort required and the value of the reward promised in return. The data were analysed using generalized linear mixed models and cluster-based permutation methods. Behaviourally, the probability of trial acceptance increased with the reward value and decreased with the required effort level. Dopamine replacement therapy increased the rate of acceptance for efforts associated with low rewards. When recording the subthalamic nucleus activity, we found a clear neural response to both reward and effort cues in the 1–10 Hz range. In addition these responses were informative of the subjective value of reward and level of effort rather than their actual quantities, such that they were predictive of the participant’s decisions. OFF levodopa, this link with acceptance was weakened. Finally, we found that these responses did not index conflict, as they did not vary as a function of the distance from indifference in the acceptance decision. These findings show

  19. The human subthalamic nucleus encodes the subjective value of reward and the cost of effort during decision-making.

    PubMed

    Zénon, Alexandre; Duclos, Yann; Carron, Romain; Witjas, Tatiana; Baunez, Christelle; Régis, Jean; Azulay, Jean-Philippe; Brown, Peter; Eusebio, Alexandre

    2016-06-01

    Adaptive behaviour entails the capacity to select actions as a function of their energy cost and expected value and the disruption of this faculty is now viewed as a possible cause of the symptoms of Parkinson's disease. Indirect evidence points to the involvement of the subthalamic nucleus-the most common target for deep brain stimulation in Parkinson's disease-in cost-benefit computation. However, this putative function appears at odds with the current view that the subthalamic nucleus is important for adjusting behaviour to conflict. Here we tested these contrasting hypotheses by recording the neuronal activity of the subthalamic nucleus of patients with Parkinson's disease during an effort-based decision task. Local field potentials were recorded from the subthalamic nucleus of 12 patients with advanced Parkinson's disease (mean age 63.8 years ± 6.8; mean disease duration 9.4 years ± 2.5) both OFF and ON levodopa while they had to decide whether to engage in an effort task based on the level of effort required and the value of the reward promised in return. The data were analysed using generalized linear mixed models and cluster-based permutation methods. Behaviourally, the probability of trial acceptance increased with the reward value and decreased with the required effort level. Dopamine replacement therapy increased the rate of acceptance for efforts associated with low rewards. When recording the subthalamic nucleus activity, we found a clear neural response to both reward and effort cues in the 1-10 Hz range. In addition these responses were informative of the subjective value of reward and level of effort rather than their actual quantities, such that they were predictive of the participant's decisions. OFF levodopa, this link with acceptance was weakened. Finally, we found that these responses did not index conflict, as they did not vary as a function of the distance from indifference in the acceptance decision. These findings show that low

  20. NIST Efforts to Quality-Assure Gunpowder Measurements

    NASA Technical Reports Server (NTRS)

    MacCrehan, William A.; Reardon, Michelle R.

    2000-01-01

    In the past few years, the National Institute for Standards and Technology (NIST) has been promoting the idea of quantitatively determining the additives in smokeless gunpowder using micellar capillary electrophoresis as a means of investigating the criminal use of hand guns and pipe bombs. As a part of this effort, we have evaluated both supercritical fluid and ultrasonic solvent extractions for the quantitative recovery of nitroglycerin (NG), diphenylamine (DPA), N-nitrosodiphenylamine (NnDPA), and ethyl centralite (EC) from gunpowder. Recoveries were evaluated by repeat extraction and matrix spiking experiments. The final extraction protocol provides greater than 95 percent recoveries. To help other researches validate their own analytical method for additive determinations, NIST is exploring the development of a standard reference material, Additives in Smokeless Gunpowder. The evaluated method is being applied to two double-base (NG-containing) powders, one stabilized with diphenylamine and the other with ethyl centralite. As part of this reference material development effort, we are conducting an interlaboratory comparison exercise among the forensic and military gunpowder measurement community.

  1. Implementing Successful Geoscience Education and Outreach Efforts

    NASA Astrophysics Data System (ADS)

    Braile, L. W.

    2004-12-01

    Successful geoscience Education and Outreach (E&O) efforts associated with a research program benefit from effective planning and a commitment by scientists/researchers to become more knowledgeable about and involved in education. Several suggested strategies have evolved based on experience in Earth science E&O with K-16 educators and students during the past 10 years. E&O programs and materials should be developed at appropriate levels ("start from where they're at") and utilize information, skills and topics that are most relevant to students and teachers. Hands-on and inquiry-based activities that teach or reinforce fundamental science understanding and skills, while introducing new topics, results and discoveries, are particularly effective. It is useful to design materials that can provide for a range of time commitment, level of technical skills, and effort, so that introductory to in-depth curriculum units can be implemented. Use of the Internet and working with teachers can be effective methods for dissemination and taking advantage of a "multiplying factor". Obtaining feedback and evaluation of the programs and developed materials, and connecting the materials to national or state education standards are also highly recommended. Most importantly, scientists should become more involved in the science education community. Attending and presenting papers at appropriate science education sessions or workshops, or state or national science teacher meetings (the annual National Science Teachers Association convention is an excellent place to start) can be a significant educational experience for the scientist/researcher. Effective geoscience E&O programs have significant potential for enhancing K-16 education and scientific literacy, and can help attract students to the sciences. Perhaps surprisingly, these efforts have substantial positive impact on the scientist/researcher as well.

  2. An iron–oxygen intermediate formed during the catalytic cycle of cysteine dioxygenase† †Electronic supplementary information (ESI) available: Experimental and computational details. See DOI: 10.1039/c6cc03904a Click here for additional data file.

    PubMed Central

    Tchesnokov, E. P.; Faponle, A. S.; Davies, C. G.; Quesne, M. G.; Turner, R.; Fellner, M.; Souness, R. J.; Wilbanks, S. M.

    2016-01-01

    Cysteine dioxygenase is a key enzyme in the breakdown of cysteine, but its mechanism remains controversial. A combination of spectroscopic and computational studies provides the first evidence of a short-lived intermediate in the catalytic cycle. The intermediate decays within 20 ms and has absorption maxima at 500 and 640 nm. PMID:27297454

  3. Overview of the Langley subsonic research effort on SCR configuration

    NASA Technical Reports Server (NTRS)

    Coe, P. L., Jr.; Thomas, J. D.; Huffman, J. K.; Weston, R. P.; Schoonover, W. E., Jr.; Gentry, C. L., Jr.

    1980-01-01

    Recent advances achieved in the subsonic aerodynamics of low aspect ratio, highly swept wing designs are summarized. The most significant of these advances was the development of leading edge deflection concepts which effectively reduce leading edge flow separation. The improved flow attachment results in substantial improvements in low speed performance, significant delay of longitudinal pitch up, increased trailing edge flap effectiveness, and increased lateral control capability. Various additional theoretical and/or experimental studies are considered which, in conjunction with the leading edge deflection studies, form the basis for future subsonic research effort.

  4. Educational Outreach Efforts at the NNDC

    SciTech Connect

    Holden, N.E.

    2014-06-15

    Isotopes and nuclides are important in our everyday life. The general public and most students are never exposed to the concepts of stable and radioactive isotopes/nuclides. The National Nuclear Data Center (NNDC) is involved in an international project to develop a Periodic Table of the Isotopes for the educational community to illustrate the importance of isotopes and nuclides in understanding the world around us. This effort should aid teachers in introducing these concepts to students from the high school to the graduate school level.

  5. Educational Outreach Efforts at the NNDC

    SciTech Connect

    Holden, N. E.

    2014-06-01

    We found that isotopes and nuclides are important in our everyday life. The general public and most students are never exposed to the concepts of stable and radioactive isotopes/nuclides. The National Nuclear Data Center (NNDC) is involved in an international project to develop a Periodic Table of the Isotopes for the educational community to illustrate the importance of isotopes and nuclides in understanding the world around us. Our effort should aid teachers in introducing these concepts to students from the high school to the graduate school level.

  6. Multipartite Entanglement Detection with Minimal Effort

    NASA Astrophysics Data System (ADS)

    Knips, Lukas; Schwemmer, Christian; Klein, Nico; Wieśniak, Marcin; Weinfurter, Harald

    2016-11-01

    Certifying entanglement of a multipartite state is generally considered a demanding task. Since an N qubit state is parametrized by 4N-1 real numbers, one might naively expect that the measurement effort of generic entanglement detection also scales exponentially with N . Here, we introduce a general scheme to construct efficient witnesses requiring a constant number of measurements independent of the number of qubits for states like, e.g., Greenberger-Horne-Zeilinger states, cluster states, and Dicke states. For four qubits, we apply this novel method to experimental realizations of the aforementioned states and prove genuine four-partite entanglement with two measurement settings only.

  7. MEMS packaging efforts at Sandia National Laboratories.

    SciTech Connect

    Custer, Jonathan Sloane

    2003-02-01

    Sandia National Laboratories has programs covering a broad range of MEMS technologies from LIGA to bulk to surface micromachining. These MEMS technologies are being considered for an equally broad range of applications, including sensors, actuators, optics, and microfluidics. As these technologies have moved from the research to the prototype product stage, packaging has been required to develop new capabilities to integrated MEMS and other technologies into functional microsystems. This paper discusses several of Sandia's MEMS packaging efforts, focusing mainly on inserting Sandia's SUMMIT V (5-level polysilicon) surface micromachining technology into fieldable microsystems.

  8. Coercion and polio eradication efforts in Moradabad

    PubMed Central

    Rentmeester, Christy A; Dasgupta, Rajib; Feemster, Kristen A; Packard, Randall M

    2014-01-01

    We introduce the problem of vaccine coercion as reported in Moradabad, India. We offer commentary and critical analysis on ethical complexities at the intersection of global public health and regional political strife and relate them to broader vaccine goals. We draw upon a historical example from malaria vaccine efforts, focusing specifically on ethical and health justice issues expressed through the use of coercion in vaccine administration. We suggest how coercion is indicative of failed leadership in public health and consider community-based collaborations as models for cultivating local investment and trust in vaccination campaigns and for success in global public health initiatives. PMID:24401293

  9. Soldier Data Tag Study Effort. Appendices,

    DTIC Science & Technology

    1985-06-10

    84-C-0146 on ,.a. SOLDIER DATA TAG " -:.,r .* STUDY EFFORT I T IT t APPENDICES to U.S. Army Soldier Support Center ATZI /ODS (Mr. Occhialini) Fort...SUPPORT CENTER * P2 DEN HARRISON, IN 46216 11 -:NG QVFZF N UAE AND ADORESS i REPORT DATE ATZI --DDS (MR. OCCHIALINI) JN 13 WAMSEROF PAGES 7-4 .’,kT N...Memorandum ATZI -DDS (14 Sep. 83) Subject: Input Requirements for SDT Cost/Benefits Analysis (CBA) , To Ch, Ofc of Analysis Spt From C, SDT, Date 5 Oct. 83

  10. Further Evidence Concerning the Effects of Perceptions of Effort and Ability on Achievement Evaluation

    ERIC Educational Resources Information Center

    Rest, Stanley; And Others

    1973-01-01

    Three experiments were reported based on the findings that perceived effort expenditure and level of ability, in addition to achievement outcome, are determinants of reward and punishment in achievement-related contexts. (Author/KM)

  11. Visual Computing Environment

    NASA Technical Reports Server (NTRS)

    Lawrence, Charles; Putt, Charles W.

    1997-01-01

    The Visual Computing Environment (VCE) is a NASA Lewis Research Center project to develop a framework for intercomponent and multidisciplinary computational simulations. Many current engineering analysis codes simulate various aspects of aircraft engine operation. For example, existing computational fluid dynamics (CFD) codes can model the airflow through individual engine components such as the inlet, compressor, combustor, turbine, or nozzle. Currently, these codes are run in isolation, making intercomponent and complete system simulations very difficult to perform. In addition, management and utilization of these engineering codes for coupled component simulations is a complex, laborious task, requiring substantial experience and effort. To facilitate multicomponent aircraft engine analysis, the CFD Research Corporation (CFDRC) is developing the VCE system. This system, which is part of NASA's Numerical Propulsion Simulation System (NPSS) program, can couple various engineering disciplines, such as CFD, structural analysis, and thermal analysis. The objectives of VCE are to (1) develop a visual computing environment for controlling the execution of individual simulation codes that are running in parallel and are distributed on heterogeneous host machines in a networked environment, (2) develop numerical coupling algorithms for interchanging boundary conditions between codes with arbitrary grid matching and different levels of dimensionality, (3) provide a graphical interface for simulation setup and control, and (4) provide tools for online visualization and plotting. VCE was designed to provide a distributed, object-oriented environment. Mechanisms are provided for creating and manipulating objects, such as grids, boundary conditions, and solution data. This environment includes parallel virtual machine (PVM) for distributed processing. Users can interactively select and couple any set of codes that have been modified to run in a parallel distributed fashion on

  12. Case Studies in Describing Scientific Research Efforts as Linked Data

    NASA Astrophysics Data System (ADS)

    Gandara, A.; Villanueva-Rosales, N.; Gates, A.

    2013-12-01

    The Web is growing with numerous scientific resources, prompting increased efforts in information management to consider integration and exchange of scientific resources. Scientists have many options to share scientific resources on the Web; however, existing options provide limited support to scientists in annotating and relating research resources resulting from a scientific research effort. Moreover, there is no systematic approach to documenting scientific research and sharing it on the Web. This research proposes the Collect-Annotate-Refine-Publish (CARP) Methodology as an approach for guiding documentation of scientific research on the Semantic Web as scientific collections. Scientific collections are structured descriptions about scientific research that make scientific results accessible based on context. In addition, scientific collections enhance the Linked Data data space and can be queried by machines. Three case studies were conducted on research efforts at the Cyber-ShARE Research Center of Excellence in order to assess the effectiveness of the methodology to create scientific collections. The case studies exposed the challenges and benefits of leveraging the Semantic Web and Linked Data data space to facilitate access, integration and processing of Web-accessible scientific resources and research documentation. As such, we present the case study findings and lessons learned in documenting scientific research using CARP.

  13. Adverse health effects of high-effort/low-reward conditions.

    PubMed

    Siegrist, J

    1996-01-01

    In addition to the person-environment fit model (J. R. French, R. D. Caplan, & R. V. Harrison, 1982) and the demand-control model (R. A. Karasek & T. Theorell, 1990), a third theoretical concept is proposed to assess adverse health effects of stressful experience at work: the effort-reward imbalance model. The focus of this model is on reciprocity of exchange in occupational life where high-cost/low-gain conditions are considered particularly stressful. Variables measuring low reward in terms of low status control (e.g., lack of promotion prospects, job insecurity) in association with high extrinsic (e.g., work pressure) or intrinsic (personal coping pattern, e.g., high need for control) effort independently predict new cardiovascular events in a prospective study on blue-collar men. Furthermore, these variables partly explain prevalence of cardiovascular risk factors (hypertension, atherogenic lipids) in 2 independent studies. Studying adverse health effects of high-effort/low-reward conditions seems well justified, especially in view of recent developments of the labor market.

  14. Food additives and preschool children.

    PubMed

    Martyn, Danika M; McNulty, Breige A; Nugent, Anne P; Gibney, Michael J

    2013-02-01

    Food additives have been used throughout history to perform specific functions in foods. A comprehensive framework of legislation is in place within Europe to control the use of additives in the food supply and ensure they pose no risk to human health. Further to this, exposure assessments are regularly carried out to monitor population intakes and verify that intakes are not above acceptable levels (acceptable daily intakes). Young children may have a higher dietary exposure to chemicals than adults due to a combination of rapid growth rates and distinct food intake patterns. For this reason, exposure assessments are particularly important in this age group. The paper will review the use of additives and exposure assessment methods and examine factors that affect dietary exposure by young children. One of the most widely investigated unfavourable health effects associated with food additive intake in preschool-aged children are suggested adverse behavioural effects. Research that has examined this relationship has reported a variety of responses, with many noting an increase in hyperactivity as reported by parents but not when assessed using objective examiners. This review has examined the experimental approaches used in such studies and suggests that efforts are needed to standardise objective methods of measuring behaviour in preschool children. Further to this, a more holistic approach to examining food additive intakes by preschool children is advisable, where overall exposure is considered rather than focusing solely on behavioural effects and possibly examining intakes of food additives other than food colours.

  15. Respiration and Reproductive Effort in Xanthium canadense

    PubMed Central

    KINUGASA, TOSHIHIKO; HIKOSAKA, KOUKI; HIROSE, TADAKI

    2005-01-01

    • Background and Aims The proportion of resources devoted to reproduction in the plant is called the reproductive effort (RE), which is most commonly expressed as the proportion of reproductive biomass to total plant biomass production (REW). Reproductive yield is the outcome of photosynthates allocated to reproductive structures minus subsequent respiratory consumption for construction and maintenance of reproductive structures. Thus, REW can differ from RE in terms of photosynthates allocated to reproductive structures (REP). • Methods Dry mass growth and respiration of vegetative and reproductive organs were measured in Xanthium canadense and the amount of photosynthates and its partitioning to dry mass growth and respiratory consumption were determined. Differences between REW and REP were analysed in terms of growth and maintenance respiration. • Key Results The fraction of allocated photosynthates that was consumed by respiration was smaller in the reproductive organ than in the vegetative organs. Consequently, REP was smaller than REW. The smaller respiratory consumption in the reproductive organ resulted from its shorter period of existence and a seasonal decline in temperature, as well as a slower rate of maintenance respiration, although the fraction of photosynthates consumed by growth respiration was larger than in the vegetative organs. • Conclusions Reproductive effort in terms of photosynthates (REP) was smaller than that in terms of biomass (REW). This difference resulted from respiratory consumption for maintenance, which was far smaller in the reproductive organ than in vegetative organs. PMID:15837721

  16. Regional Effort to Deploy Clean Coal Technologies

    SciTech Connect

    Gerald Hill; Kenneth Nemeth; Gary Garrett; Kimberly Sams

    2009-01-31

    The Southern States Energy Board's (SSEB) 'Regional Effort to Deploy Clean Coal Technologies' program began on June 1, 2003, and was completed on January 31, 2009. The project proved beneficial in providing state decision-makers with information that assisted them in removing barriers or implementing incentives to deploy clean coal technologies. This was accomplished through two specific tasks: (1) domestic energy security and diversity; and (2) the energy-water interface. Milestones accomplished during the project period are: (1) Presentations to Annual Meetings of SSEB Members, Associate Member Meetings, and the Gasification Technologies Council. (2) Energy: Water reports - (A) Regional Efforts to Deploy Clean Coal Technologies: Impacts and Implications for Water Supply and Quality. June 2004. (B) Energy-Water Interface Challenges: Coal Bed Methane and Mine Pool Water Characterization in the Southern States Region. 2004. (C) Freshwater Availability and Constraints on Thermoelectric Power Generation in the Southeast U.S. June 2008. (3) Blackwater Interactive Tabletop Exercise - Decatur, Georgia April 2007. (4) Blackwater Report: Blackwater: Energy and Water Interdependency Issues: Best Practices and Lessons Learned. August 2007. (5) Blackwater Report: BLACKWATER: Energy Water Interdependency Issues REPORT SUMMARY. April 2008.

  17. Sidoarjo mudflow phenomenon and its mitigation efforts

    NASA Astrophysics Data System (ADS)

    Wibowo, H. T.; Williams, V.

    2009-12-01

    Hot mud first erupted in Siring village, Porong, Sidoarjo May 29th 2006. The mud first appeared approximately 200 meters from Banjarpanji-1 gas-drilling well. The mud volume increased day by day, from 5000 cubic meters per day on June 2006 to 50,000 cubic meters per day during the last of 2006, and then increased to 100,000-120,000 cubic meters per day during 2007. Flow still continues at a high rate. Moreover, as the water content has gone down, the clast content has gone up. Consequently, there is now the threat of large amounts of solid material being erupted throughout the area. Also, there is the issue of subsurface collapse and ground surface subsidence. The Indonesian government has set up a permanent team to support communities affected by the mudflow that has swamped a number of villages near LUSI. Toll roads, railway tracks and factories also have been submerged and over 35,000 people have been displaced to date. The Sidoarjo Mudflow Mitigation Agency [SMMA, BPLS (Indonesia)] replaces a temporary team called National Team PSLS which was installed for seven months and ended their work on 7 April 2007. BPLS was set up by Presidential Regulation No. 14 / 2007, and it will have to cover the costs related to the social impact of the disaster, especially outside the swamped area. BPLS is the central government institution designated to handle the disaster by coordination with both the drilling company and local (provincial and district) governments. It takes a comprehensive, integrated and holistic approach for its mission and challenges. Those are: 1) How to stop the mudflow, 2) How to mitigate the impacts of the mudflow, and 3) How to minimize the social, economic, environmental impacts, and infrastructure impacts. The mudflow mitigation efforts were constrained by dynamic geology conditions, as well as resistance to certain measures by residents of impacted areas. Giant dykes were built to retain the spreading mud, and the mudflow from the main vent was

  18. Current status of the MPEG-4 standardization effort

    NASA Astrophysics Data System (ADS)

    Anastassiou, Dimitris

    1994-09-01

    The Moving Pictures Experts Group (MPEG) of the International Standardization Organization has initiated a standardization effort, known as MPEG-4, addressing generic audiovisual coding at very low bit-rates (up to 64 kbits/s) with applications in videotelephony, mobile audiovisual communications, video database retrieval, computer games, video over Internet, remote sensing, etc. This paper gives a survey of the status of MPEG-4, including its planned schedule, and initial ideas about requirements and applications. A significant part of this paper is summarizing an incomplete draft version of a `requirements document' which presents specifications of desirable features on the video, audio, and system level of the forthcoming standard. Very low bit-rate coding algorithms are not described, because no endorsement of any particular algorithm, or class of algorithms, has yet been made by MPEG-4, and several seminars held concurrently with MPEG-4 meetings have not so far provided evidence that such high performance coding schemes are achievable.

  19. Results and current status of the NPARC alliance validation effort

    NASA Technical Reports Server (NTRS)

    Towne, Charles E.; Jones, Ralph R.

    1996-01-01

    The NPARC Alliance is a partnership between the NASA Lewis Research Center (LeRC) and the USAF Arnold Engineering Development Center (AEDC) dedicated to the establishment of a national CFD capability, centered on the NPARC Navier-Stokes computer program. The three main tasks of the Alliance are user support, code development, and validation. The present paper is a status report on the validation effort. It describes the validation approach being taken by the Alliance. Representative results are presented for laminar and turbulent flat plate boundary layers, a supersonic axisymmetric jet, and a glancing shock/turbulent boundary layer interaction. Cases scheduled to be run in the future are also listed. The archive of validation cases is described, including information on how to access it via the Internet.

  20. Separate and overlapping brain areas encode subjective value during delay and effort discounting.

    PubMed

    Massar, Stijn A A; Libedinsky, Camilo; Weiyan, Chee; Huettel, Scott A; Chee, Michael W L

    2015-10-15

    Making decisions about rewards that involve delay or effort requires the integration of value and cost information. The brain areas recruited in this integration have been well characterized for delay discounting. However only a few studies have investigated how effort costs are integrated into value signals to eventually determine choice. In contrast to previous studies that have evaluated fMRI signals related to physical effort, we used a task that focused on cognitive effort. Participants discounted the value of delayed and effortful rewards. The value of cognitively effortful rewards was represented in the anterior portion of the inferior frontal gyrus and dorsolateral prefrontal cortex. Additionally, the value of the chosen option was encoded in the anterior cingulate cortex, caudate, and cerebellum. While most brain regions showed no significant dissociation between effort discounting and delay discounting, the ACC was significantly more activated in effort compared to delay discounting tasks. Finally, overlapping regions within the right orbitofrontal cortex and lateral temporal and parietal cortices encoded the value of the chosen option during both delay and effort discounting tasks. These results indicate that encoding of rewards discounted by cognitive effort and delay involves partially dissociable brain areas, but a common representation of chosen value is present in the orbitofrontal, temporal and parietal cortices.

  1. Mars Exploration Rovers Launch Contingency Efforts

    NASA Astrophysics Data System (ADS)

    McGrath, Brian E.; Frostbutter, David A.; Parthasarathy, Karungulam N.; Heyler, Gene A.; Chang, Yale

    2004-02-01

    On 10 June 2003 at 1:58 p.m. Eastern Daylight Time (EDT) and 7 July 2003 at 11:18 p.m. EDT, two separate spacecraft/rovers were successfully launched to Mars atop a Delta II 7925 and Delta II 7925H, respectively. Each spacecraft/rover carried eight Light Weight Radioisotope Heater Units (LWRHUs) for thermal conditioning of electronics during the cold Martian nights. As a part of the joint National Aeronautics and Space Administration/U. S. Department of Energy safety effort, a contingency plan was prepared to address the unlikely events of an accidental suborbital reentry or out-of-orbit reentry. The objective of the contingency plan was to develop and implement procedures to predict, within the first hour, the probable Earth Impact Footprints (EIFs) for the LWRHUs or other possible spacecraft debris after an accidental reentry. No ablation burn-through of the heat sources' aeroshells was expected, as a result of earlier testing. Any predictions would be used in subsequent notification and recovery efforts. The Johns Hopkins University Applied Physics Laboratory, as part of a multi-agency team, was responsible for prediction of the EIFs, and the time of reentry from a potential orbital decay. The tools used to predict the EIFs included a Three-Degree-of-Freedom (3DOF) trajectory simulation code, a Six-Degree-of-Freedom (6DOF) code, a database of aerodynamic coefficients for the LWRHUs and other spacecraft debris, secure links to obtain tracking data, and a high fidelity special perturbation orbit integrator code to predict time of spacecraft reentry from orbital decay. This paper will discuss the contingency plan and process, as well as highlight the improvements made to the analytical tools. Improvements to the 3DOF, aerodynamic database, and orbit integrator and inclusion of the 6DOF have significantly enhanced the prediction capabilities. In the days before launch, the trajectory simulation codes were exercised and predictions of hypothetical EIFs were produced

  2. Computers in Psychotherapy: An Overview.

    ERIC Educational Resources Information Center

    Plutchik, Robert; Karasu, Toksoz B.

    1991-01-01

    Reviews the literature dealing with the role of computers in psychiatric interviewing, and with the role of the computer as a patient or as a therapist. Efforts to develop forms of computer-assisted therapy are described, and implications for the mental health field are suggested. (40 references) (LRW)

  3. Computer viruses

    NASA Technical Reports Server (NTRS)

    Denning, Peter J.

    1988-01-01

    The worm, Trojan horse, bacterium, and virus are destructive programs that attack information stored in a computer's memory. Virus programs, which propagate by incorporating copies of themselves into other programs, are a growing menace in the late-1980s world of unprotected, networked workstations and personal computers. Limited immunity is offered by memory protection hardware, digitally authenticated object programs,and antibody programs that kill specific viruses. Additional immunity can be gained from the practice of digital hygiene, primarily the refusal to use software from untrusted sources. Full immunity requires attention in a social dimension, the accountability of programmers.

  4. Computer systems

    NASA Technical Reports Server (NTRS)

    Olsen, Lola

    1992-01-01

    In addition to the discussions, Ocean Climate Data Workshop hosts gave participants an opportunity to hear about, see, and test for themselves some of the latest computer tools now available for those studying climate change and the oceans. Six speakers described computer systems and their functions. The introductory talks were followed by demonstrations to small groups of participants and some opportunities for participants to get hands-on experience. After this familiarization period, attendees were invited to return during the course of the Workshop and have one-on-one discussions and further hands-on experience with these systems. Brief summaries or abstracts of introductory presentations are addressed.

  5. Piezoelectric and electromagnetic respiratory effort energy harvesters.

    PubMed

    Shahhaidar, Ehsaneh; Padasdao, Bryson; Romine, R; Stickley, C; Boric-Lubecke, Olga

    2013-01-01

    The movements of the torso due to normal breathing could be harvested as an alternative, and renewable power source for an ultra-low power electronic device. The same output signal could also be recorded as a physiological signal containing information about breathing, thus enabling self-powered wearable biosensors/harvesters. In this paper, the selection criteria for such a biosensor, optimization procedure, trade-offs, and challenges as a sensor and harvester are presented. The empirical data obtained from testing different modules on a mechanical torso and a human subject demonstrated that an electromagnetic generator could be used as an unobtrusive self-powered medical sensor by harvesting more power, offering reasonable amount of output voltage for rectification purposes, and detecting respiratory effort.

  6. Advancing efforts to address youth violence involvement.

    PubMed

    Weist, M D; Cooley-Quille, M

    2001-06-01

    Discusses the increased public attention on violence-related problems among youth and the concomitant increased diversity in research. Youth violence involvement is a complex construct that includes violence experienced in multiple settings (home, school, neighborhood) and in multiple forms (as victims, witnesses, perpetrators, and through family members, friends, and the media). Potential impacts of such violence involvement are considerable, including increased internalizing and externalizing behaviors among youth and future problems in school adjustment and life-course development. This introductory article reviews key dimensions of youth-related violence, describes an American Psychological Association Task Force (Division 12) developed to advance relevant research, and presents examples of national resources and efforts that attempt to address this critical public health issue.

  7. The NOAA-NASA CZCS Reanalysis Effort

    NASA Technical Reports Server (NTRS)

    Gregg, Watson W.; Conkright, Margarita E.; OReilly, John E.; Patt, Frederick S.; Wang, Meng-Hua; Yoder, James; Casey-McCabe, Nancy; Koblinsky, Chester J. (Technical Monitor)

    2001-01-01

    Satellite observations of global ocean chlorophyll span over two decades. However, incompatibilities between processing algorithms prevent us from quantifying natural variability. We applied a comprehensive reanalysis to the Coastal Zone Color Scanner (CZCS) archive, called the NOAA-NASA CZCS Reanalysis (NCR) Effort. NCR consisted of 1) algorithm improvement (AI), where CZCS processing algorithms were improved using modernized atmospheric correction and bio-optical algorithms, and 2) blending, where in situ data were incorporated into the CZCS AI to minimize residual errors. The results indicated major improvement over the previously available CZCS archive. Global spatial and seasonal patterns of NCR chlorophyll indicated remarkable correspondence with modern sensors, suggesting compatibility. The NCR permits quantitative analyses of interannual and interdecadal trends in global ocean chlorophyll.

  8. Directed-energy process technology efforts

    NASA Technical Reports Server (NTRS)

    Alexander, P.

    1985-01-01

    A summary of directed-energy process technology for solar cells was presented. This technology is defined as directing energy or mass to specific areas on solar cells to produce a desired effect in contrast to exposing a cell to a thermal or mass flow environment. Some of these second generation processing techniques are: ion implantation; microwave-enhanced chemical vapor deposition; rapid thermal processing; and the use of lasers for cutting, assisting in metallization, assisting in deposition, and drive-in of liquid dopants. Advantages of directed energy techniques are: surface heating resulting in the bulk of the cell material being cooler and unchanged; better process control yields; better junction profiles, junction depths, and metal sintering; lower energy consumption during processing and smaller factory space requirements. These advantages should result in higher-efficiency cells at lower costs. The results of the numerous contracted efforts were presented as well as the application potentials of these new technologies.

  9. Two groups challenge US acid rain efforts

    SciTech Connect

    Not Available

    1987-11-01

    In its report, Acid Rain Invades Our National Parks, the National Parks and Conservation Association (NPCA) says acid rain is being detected at all 27 national park monitoring sites. In 1980, 87 national parks expressed concern in a NPCA survey over acid rain. Repolled in 1986, more than half of the respondents reported that no research on acid rain was under way. The NPCA report concludes that the alarm that was sounded in 1980 fell largely on deaf ears, and calls for the structural and scientific reorganization of the National Park Service. The National Audubon Society shares NPCA's dissatisfaction with federal efforts to tackle the problem of acid rain and has taken testing into its own hands. Through its Citizens Acid Rain Monitoring Network, Audubon volunteers have collected readings of acidity at 64 monitoring stations in 31 states since July.

  10. Computational chemistry

    NASA Technical Reports Server (NTRS)

    Arnold, J. O.

    1987-01-01

    With the advent of supercomputers, modern computational chemistry algorithms and codes, a powerful tool was created to help fill NASA's continuing need for information on the properties of matter in hostile or unusual environments. Computational resources provided under the National Aerodynamics Simulator (NAS) program were a cornerstone for recent advancements in this field. Properties of gases, materials, and their interactions can be determined from solutions of the governing equations. In the case of gases, for example, radiative transition probabilites per particle, bond-dissociation energies, and rates of simple chemical reactions can be determined computationally as reliably as from experiment. The data are proving to be quite valuable in providing inputs to real-gas flow simulation codes used to compute aerothermodynamic loads on NASA's aeroassist orbital transfer vehicles and a host of problems related to the National Aerospace Plane Program. Although more approximate, similar solutions can be obtained for ensembles of atoms simulating small particles of materials with and without the presence of gases. Computational chemistry has application in studying catalysis, properties of polymers, all of interest to various NASA missions, including those previously mentioned. In addition to discussing these applications of computational chemistry within NASA, the governing equations and the need for supercomputers for their solution is outlined.

  11. Prioritizing earthquake and tsunami alerting efforts

    NASA Astrophysics Data System (ADS)

    Allen, R. M.; Allen, S.; Aranha, M. A.; Chung, A. I.; Hellweg, M.; Henson, I. H.; Melgar, D.; Neuhauser, D. S.; Nof, R. N.; Strauss, J. A.

    2015-12-01

    The timeline of hazards associated with earthquakes ranges from seconds for the strong shaking at the epicenter, to minutes for strong shaking at more distant locations in big quakes, to tens of minutes for a local tsunami. Earthquake and tsunami warning systems must therefore include very fast initial alerts, while also taking advantage of available time in bigger and tsunami-generating quakes. At the UC Berkeley Seismological Laboratory we are developing a suite of algorithms to provide the fullest possible information about earthquake shaking and tsunami inundation from seconds to minutes after a quake. The E-larmS algorithm uses the P-wave to rapidly detect an earthquake and issue a warning. It is currently issuing alerts to test users in as little as 3 sec after the origin time. Development of a new waveform detector may lead to even faster alerts. G-larmS uses permanent deformation estimates from GNSS stations to estimate the geometry and extent of rupture underway providing more accurate ground shaking estimates in big (M>~7) earthquakes. It performed well in the M6.0 2014 Napa earthquake. T-larmS is a new algorithm designed to extend alert capabilities to tsunami inundation. Rapid estimates of source characteristics for subduction zones event can not only be used to warn of the shaking hazard, but also the local tsunami inundation hazard. These algorithms are being developed, implemented and tested with a focus on the western US, but are also now being tested in other parts of the world including Israel, Turkey, Korea and Chile. Beta users in the Bay Area are receiving the alerts and beginning to implement automated actions. They also provide feedback on users needs, which has led to the development of the MyEEW smartphone app. This app allows beta users to receive the alerts on their cell phones. All these efforts feed into our ongoing assessment of directions and priorities for future development and implementation efforts.

  12. AVOLITION IN SCHIZOPHRENIA IS ASSOCIATED WITH REDUCED WILLINGNESS TO EXPEND EFFORT FOR REWARD ON A PROGRESSIVE RATIO TASK

    PubMed Central

    Strauss, Gregory P.; Whearty, Kayla M.; Morra, Lindsay F.; Sullivan, Sara K.; Ossenfort, Kathryn L.; Frost, Katherine H.

    2015-01-01

    The current study examined whether effort-cost computation was associated with negative symptoms of schizophrenia (SZ). Participants included outpatients diagnosed with SZ (n = 27) and demographically matched healthy controls (n = 32) who completed a Progressive Ratio Task that required incrementally greater amounts of physical effort to obtain monetary reward. Breakpoint, the point at which participants were no longer willing to exert effort for a certain reward value, was examined as an index of effort-cost computation. There were no group differences in breakpoint for low, medium, or high value rewards on the Progressive Ratio Task. However, lower breakpoint scores were associated with greater severity of avolition and anhedonia symptoms in SZ patients. Findings provide further evidence that impaired effort-cost computation is linked to motivational abnormalities in SZ. PMID:26701649

  13. Avolition in schizophrenia is associated with reduced willingness to expend effort for reward on a Progressive Ratio task.

    PubMed

    Strauss, Gregory P; Whearty, Kayla M; Morra, Lindsay F; Sullivan, Sara K; Ossenfort, Kathryn L; Frost, Katherine H

    2016-01-01

    The current study examined whether effort-cost computation was associated with negative symptoms of schizophrenia (SZ). Participants included outpatients diagnosed with SZ (n=27) and demographically matched healthy controls (n=32) who completed a Progressive Ratio task that required incrementally greater amounts of physical effort to obtain monetary reward. Breakpoint, the point at which participants was no longer willing to exert effort for a certain reward value, was examined as an index of effort-cost computation. There were no group differences in breakpoint for low, medium, or high value rewards on the Progressive Ratio task. However, lower breakpoint scores were associated with greater severity of avolition and anhedonia symptoms in SZ patients. Findings provide further evidence that impaired effort-cost computation is linked to motivational abnormalities in SZ.

  14. Changing computing paradigms towards power efficiency

    PubMed Central

    Klavík, Pavel; Malossi, A. Cristiano I.; Bekas, Costas; Curioni, Alessandro

    2014-01-01

    Power awareness is fast becoming immensely important in computing, ranging from the traditional high-performance computing applications to the new generation of data centric workloads. In this work, we describe our efforts towards a power-efficient computing paradigm that combines low- and high-precision arithmetic. We showcase our ideas for the widely used kernel of solving systems of linear equations that finds numerous applications in scientific and engineering disciplines as well as in large-scale data analytics, statistics and machine learning. Towards this goal, we developed tools for the seamless power profiling of applications at a fine-grain level. In addition, we verify here previous work on post-FLOPS/W metrics and show that these can shed much more light in the power/energy profile of important applications. PMID:24842033

  15. Cleavage of ether, ester, and tosylate C(sp3)-O bonds by an iridium complex, initiated by oxidative addition of C-H bonds. Experimental and computational studies.

    PubMed

    Kundu, Sabuj; Choi, Jongwook; Wang, David Y; Choliy, Yuriy; Emge, Thomas J; Krogh-Jespersen, Karsten; Goldman, Alan S

    2013-04-03

    A pincer-ligated iridium complex, (PCP)Ir (PCP = κ(3)-C6H3-2,6-[CH2P(t-Bu)2]2), is found to undergo oxidative addition of C(sp(3))-O bonds of methyl esters (CH3-O2CR'), methyl tosylate (CH3-OTs), and certain electron-poor methyl aryl ethers (CH3-OAr). DFT calculations and mechanistic studies indicate that the reactions proceed via oxidative addition of C-H bonds followed by oxygenate migration, rather than by direct C-O addition. Thus, methyl aryl ethers react via addition of the methoxy C-H bond, followed by α-aryloxide migration to give cis-(PCP)Ir(H)(CH2)(OAr), followed by iridium-to-methylidene hydride migration to give (PCP)Ir(CH3)(OAr). Methyl acetate undergoes C-H bond addition at the carbomethoxy group to give (PCP)Ir(H)[κ(2)-CH2OC(O)Me] which then affords (PCP-CH2)Ir(H)(κ(2)-O2CMe) (6-Me) in which the methoxy C-O bond has been cleaved, and the methylene derived from the methoxy group has migrated into the PCP Cipso-Ir bond. Thermolysis of 6-Me ultimately gives (PCP)Ir(CH3)(κ(2)-O2CR), the net product of methoxy group C-O oxidative addition. Reaction of (PCP)Ir with species of the type ROAr, RO2CMe or ROTs, where R possesses β-C-H bonds (e.g., R = ethyl or isopropyl), results in formation of (PCP)Ir(H)(OAr), (PCP)Ir(H)(O2CMe), or (PCP)Ir(H)(OTs), respectively, along with the corresponding olefin or (PCP)Ir(olefin) complex. Like the C-O bond oxidative additions, these reactions also proceed via initial activation of a C-H bond; in this case, C-H addition at the β-position is followed by β-migration of the aryloxide, carboxylate, or tosylate group. Calculations indicate that the β-migration of the carboxylate group proceeds via an unusual six-membered cyclic transition state in which the alkoxy C-O bond is cleaved with no direct participation by the iridium center.

  16. Altering Effort Costs in Parkinson's Disease with Noninvasive Cortical Stimulation

    PubMed Central

    Salimpour, Yousef; Mari, Zoltan K.

    2015-01-01

    noninvasive cortical stimulation. In addition to reducing effort costs associated with the affected arm, the cortical stimulation also improved clinical motor symptoms of the disease. PMID:26338339

  17. Community Efforts Bringing Research on Learning to the Geosciences

    NASA Astrophysics Data System (ADS)

    Manduca, C. A.; Mogk, D. W.; Kastens, K. A.

    2009-12-01

    synthesis of research on learning in the geosciences is currently expanding the interdisciplinary base for research on geoscience teaching and learning through the collaborative development of papers addressing spatial thinking, geologic time, complex systems, and learning in the field. Participants in this project include anthropologists and philosophers in addition to geologists, oceanographers, atmospheric scientists, education researches and psychologists. The project is currently seeking commentators to respond to an initial set of papers and has initiated the Earth and Mind blog as a mechanism for increased discussion and community interaction. This project builds on the GSA special volume ‘Earth and Mind’ which included writing by geoscience researchers, psychologists and education researchers addressing how we teach and learn about the Earth. These community efforts are an essential aspect of scientific research supporting discussion and synthesis of results and generation of new questions. The breadth of participants in this community indicates the importance of the work within and beyond the geosciences and is an indicator of its robustness.

  18. Cloud Computing: An Overview

    NASA Astrophysics Data System (ADS)

    Qian, Ling; Luo, Zhiguo; Du, Yujian; Guo, Leitao

    In order to support the maximum number of user and elastic service with the minimum resource, the Internet service provider invented the cloud computing. within a few years, emerging cloud computing has became the hottest technology. From the publication of core papers by Google since 2003 to the commercialization of Amazon EC2 in 2006, and to the service offering of AT&T Synaptic Hosting, the cloud computing has been evolved from internal IT system to public service, from cost-saving tools to revenue generator, and from ISP to telecom. This paper introduces the concept, history, pros and cons of cloud computing as well as the value chain and standardization effort.

  19. Predicting Pilot Error in Nextgen: Pilot Performance Modeling and Validation Efforts

    NASA Technical Reports Server (NTRS)

    Wickens, Christopher; Sebok, Angelia; Gore, Brian; Hooey, Becky

    2012-01-01

    We review 25 articles presenting 5 general classes of computational models to predict pilot error. This more targeted review is placed within the context of the broader review of computational models of pilot cognition and performance, including such aspects as models of situation awareness or pilot-automation interaction. Particular emphasis is placed on the degree of validation of such models against empirical pilot data, and the relevance of the modeling and validation efforts to Next Gen technology and procedures.

  20. Biocellion: accelerating computer simulation of multicellular biological system models

    PubMed Central

    Kang, Seunghwa; Kahan, Simon; McDermott, Jason; Flann, Nicholas; Shmulevich, Ilya

    2014-01-01

    Motivation: Biological system behaviors are often the outcome of complex interactions among a large number of cells and their biotic and abiotic environment. Computational biologists attempt to understand, predict and manipulate biological system behavior through mathematical modeling and computer simulation. Discrete agent-based modeling (in combination with high-resolution grids to model the extracellular environment) is a popular approach for building biological system models. However, the computational complexity of this approach forces computational biologists to resort to coarser resolution approaches to simulate large biological systems. High-performance parallel computers have the potential to address the computing challenge, but writing efficient software for parallel computers is difficult and time-consuming. Results: We have developed Biocellion, a high-performance software framework, to solve this computing challenge using parallel computers. To support a wide range of multicellular biological system models, Biocellion asks users to provide their model specifics by filling the function body of pre-defined model routines. Using Biocellion, modelers without parallel computing expertise can efficiently exploit parallel computers with less effort than writing sequential programs from scratch. We simulate cell sorting, microbial patterning and a bacterial system in soil aggregate as case studies. Availability and implementation: Biocellion runs on x86 compatible systems with the 64 bit Linux operating system and is freely available for academic use. Visit http://biocellion.com for additional information. Contact: seunghwa.kang@pnnl.gov PMID:25064572

  1. CFD Based Computations of Flexible Helicopter Blades for Stability Analysis

    NASA Technical Reports Server (NTRS)

    Guruswamy, Guru P.

    2011-01-01

    As a collaborative effort among government aerospace research laboratories an advanced version of a widely used computational fluid dynamics code, OVERFLOW, was recently released. This latest version includes additions to model flexible rotating multiple blades. In this paper, the OVERFLOW code is applied to improve the accuracy of airload computations from the linear lifting line theory that uses displacements from beam model. Data transfers required at every revolution are managed through a Unix based script that runs jobs on large super-cluster computers. Results are demonstrated for the 4-bladed UH-60A helicopter. Deviations of computed data from flight data are evaluated. Fourier analysis post-processing that is suitable for aeroelastic stability computations are performed.

  2. Achieving National Unity of Effort in Cyber

    DTIC Science & Technology

    2011-06-16

    Corporation for Assigned Names and Numbers, which includes functions referred to as the Internet Assigned Numbers Authority ( ICANN ) Supervises the...economy is what enables the rest of U.S. power. In addition, the FCA should partner 50 with existing civilian organizations (e.g. ICANN , ITU, IETF and

  3. Heterogeneous Distributed Computing for Computational Aerosciences

    NASA Technical Reports Server (NTRS)

    Sunderam, Vaidy S.

    1998-01-01

    The research supported under this award focuses on heterogeneous distributed computing for high-performance applications, with particular emphasis on computational aerosciences. The overall goal of this project was to and investigate issues in, and develop solutions to, efficient execution of computational aeroscience codes in heterogeneous concurrent computing environments. In particular, we worked in the context of the PVM[1] system and, subsequent to detailed conversion efforts and performance benchmarking, devising novel techniques to increase the efficacy of heterogeneous networked environments for computational aerosciences. Our work has been based upon the NAS Parallel Benchmark suite, but has also recently expanded in scope to include the NAS I/O benchmarks as specified in the NHT-1 document. In this report we summarize our research accomplishments under the auspices of the grant.

  4. Obtaining information by dynamic (effortful) touching

    PubMed Central

    Turvey, M. T.; Carello, Claudia

    2011-01-01

    Dynamic touching is effortful touching. It entails deformation of muscles and fascia and activation of the embedded mechanoreceptors, as when an object is supported and moved by the body. It is realized as exploratory activities that can vary widely in spatial and temporal extents (a momentary heft, an extended walk). Research has revealed the potential of dynamic touching for obtaining non-visual information about the body (e.g. limb orientation), attachments to the body (e.g. an object's height and width) and the relation of the body both to attachments (e.g. hand's location on a grasped object) and surrounding surfaces (e.g. places and their distances). Invariants over the exploratory activity (e.g. moments of a wielded object's mass distribution) seem to ground this ‘information about’. The conception of a haptic medium as a nested tensegrity structure has been proposed to express the obtained information realized by myofascia deformation, by its invariants and transformations. The tensegrity proposal rationalizes the relative indifference of dynamic touch to the site of mechanical contact (hand, foot, torso or probe) and the overtness of exploratory activity. It also provides a framework for dynamic touching's fractal nature, and the finding that its degree of fractality may matter to its accomplishments. PMID:21969694

  5. Regionally Applied Research Efforts (RARE) Report titled " ...

    EPA Pesticide Factsheets

    The traditional methodology for health risk assessment used by the U. S. Environmental Protection Agency (EPA) is based on the use of exposure assumptions (e.g. exposure duration, food ingestion rate, body weight, etc.) that represent the entire American population, either as a central tendency exposure (e.g. average, median) or as a reasonable maximum exposure (e.g. 95% upper confidence limit). Unfortunately, EPA lacked exposure information for assessing health risks for New England regional tribes sustaining a tribal subsistence way of life. As a riverine tribe, the Penobscot culture and traditions are inextricably tied to the Penobscot River watershed. It is through hunting, fishing, trapping, gathering and making baskets, pottery, moccasins, birch-bark canoes and other traditional practices that the Penobscot culture and people are sustained. The Penobscot River receives a variety of pollutant discharges leaving the Penobscot Indian Nation (PIN) questioning the ecological health and water quality of the river and how this may affect the practices that sustain their way of life. The objectives of this Regional Applied Research Effort (RARE) study were to: (1) Develop culturally sensitive methodologies for assessing the potential level of exposure to contaminants that Penobscot Indian Nation tribal members may have from maintaining tribal sustenance practices; (2) Conduct field surveys and laboratory analysis on targeted flora and fauna for chemical expo

  6. STEM Education Efforts in the Ares Projects

    NASA Technical Reports Server (NTRS)

    Doreswamy, Rajiv; Armstrong, Robert C.

    2010-01-01

    According to the National Science Foundation, of the more than 4 million first university degrees awarded in science and engineering in 2006, students in China earned about 21%, those in the European Union earned about 19%, and those in the United States earned about 11%. Statistics like these are of great interest to NASA's Ares Projects, which are responsible for building the rockets for the U.S. Constellation Program to send humans beyond low-Earth orbit. Science, technology, engineering, and mathematics students are essential for the long-term sustainability of any space program. Since the Projects creation, the Ares Outreach Team has used a variety of STEM-related media, methods, and materials to engage students, educators, and the general public in Constellation's mission. Like Project Apollo, the nation s exploration destinations and the vehicles used to get there can inspire students to learn more about STEM. Ares has been particularly active in public outreach to schools in Northern Alabama; on the Internet via outreach and grade-specific educational materials; and in more informal social media settings such as YouTube and Facebook. These combined efforts remain integral to America s space program, regardless of its future direction.

  7. Sodium intake reduction efforts in Lebanon

    PubMed Central

    Almedawar, Mohamad M.; Nasreddine, Lara; Olabi, Ammar; Hamade, Haya; Awad, Elie; Toufeili, Imad; Arnaout, Samir

    2015-01-01

    Sodium intake reduction efforts in Lebanon are quite recent and have just started to take effect on the national level. Starting out from an academic institution, the Lebanese Action on Sodium and Health (LASH) campaign was established to counter the increasing prevalence of hypertension and associated adverse health effects. The campaign’s strategy was based on four pillars: research, health communication, advocacy, and monitoring. The LASH group set out with determining: baseline sodium intake of the population, main sources of sodium intake, and the knowledge, attitudes, and behaviors (KAB) of the population as a situation analysis that prompts for action. This gave LASH tangible evidence of the magnitude of the problem and the need for the government, the food industry, and the consumers, to be mobilized to take part in devising a solution. Currently, Lebanon is at a stage of technically working to reduce the sodium content in the major sources of sodium, namely local bread and bread-like products. The next steps will include implementation of a plan for monitoring industry compliance, while studying other food targets, including dairy products and processed meat. Meanwhile, the health communication plan is ongoing and the Salt Awareness Week is celebrated every year with media appearances of LASH researchers to raise the issue to the public eye. PMID:26090328

  8. NREL Quickens its Tech Transfer Efforts

    SciTech Connect

    Lammers, H.

    2012-02-01

    Innovations and 'aha' movements in renewable energy and energy efficiency, while exciting in the lab, only truly live up to their promise once they find a place in homes or business. Late last year President Obama issued a directive to all federal agencies to increase their efforts to transfer technologies to the private sector in order to achieve greater societal and economic impacts of federal research investments. The president's call to action includes efforts to establish technology transfer goals and to measure progress, to engage in efforts to increase the speed of technology transfer and to enhance local and regional innovation partnerships. But, even before the White House began its initiative to restructure the commercialization process, the National Renewable Energy Laboratory had a major effort underway designed to increase the speed and impact of technology transfer activities and had already made sure its innovations had a streamlined path to the private sector. For the last three years, NREL has been actively setting commercialization goals and tracking progress against those goals. For example, NREL sought to triple the number of innovations over a five-year period that began in 2009. Through best practices associated with inventor engagement, education and collaboration, NREL quadrupled the number of innovations in just three years. Similar progress has been made in patenting, licensing transactions, income generation and rewards to inventors. 'NREL is known nationally for our cutting-edge research and companies know to call us when they are ready to collaborate,' William Farris, vice president for commercialization and technology transfer, said. 'Once a team is ready to dive in, they don't want be mired in paperwork. We've worked to make our process for licensing NREL technology faster; it now takes less than 60 days for us to come to an agreement and start work with a company interested in our research.' While NREL maintains a robust patent

  9. Making intelligent systems team players: Additional case studies

    NASA Technical Reports Server (NTRS)

    Malin, Jane T.; Schreckenghost, Debra L.; Rhoads, Ron W.

    1993-01-01

    Observations from a case study of intelligent systems are reported as part of a multi-year interdisciplinary effort to provide guidance and assistance for designers of intelligent systems and their user interfaces. A series of studies were conducted to investigate issues in designing intelligent fault management systems in aerospace applications for effective human-computer interaction. The results of the initial study are documented in two NASA technical memoranda: TM 104738 Making Intelligent Systems Team Players: Case Studies and Design Issues, Volumes 1 and 2; and TM 104751, Making Intelligent Systems Team Players: Overview for Designers. The objective of this additional study was to broaden the investigation of human-computer interaction design issues beyond the focus on monitoring and fault detection in the initial study. The results of this second study are documented which is intended as a supplement to the original design guidance documents. These results should be of interest to designers of intelligent systems for use in real-time operations, and to researchers in the areas of human-computer interaction and artificial intelligence.

  10. 24 CFR 103.325 - Termination of conciliation efforts.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Termination of conciliation efforts... conciliation efforts. (a) HUD may terminate its efforts to conciliate the complaint if the respondent fails or refuses to confer with HUD; the aggrieved person or the respondent fail to make a good faith effort...

  11. Computational mechanics

    SciTech Connect

    Goudreau, G.L.

    1993-03-01

    The Computational Mechanics thrust area sponsors research into the underlying solid, structural and fluid mechanics and heat transfer necessary for the development of state-of-the-art general purpose computational software. The scale of computational capability spans office workstations, departmental computer servers, and Cray-class supercomputers. The DYNA, NIKE, and TOPAZ codes have achieved world fame through our broad collaborators program, in addition to their strong support of on-going Lawrence Livermore National Laboratory (LLNL) programs. Several technology transfer initiatives have been based on these established codes, teaming LLNL analysts and researchers with counterparts in industry, extending code capability to specific industrial interests of casting, metalforming, and automobile crash dynamics. The next-generation solid/structural mechanics code, ParaDyn, is targeted toward massively parallel computers, which will extend performance from gigaflop to teraflop power. Our work for FY-92 is described in the following eight articles: (1) Solution Strategies: New Approaches for Strongly Nonlinear Quasistatic Problems Using DYNA3D; (2) Enhanced Enforcement of Mechanical Contact: The Method of Augmented Lagrangians; (3) ParaDyn: New Generation Solid/Structural Mechanics Codes for Massively Parallel Processors; (4) Composite Damage Modeling; (5) HYDRA: A Parallel/Vector Flow Solver for Three-Dimensional, Transient, Incompressible Viscous How; (6) Development and Testing of the TRIM3D Radiation Heat Transfer Code; (7) A Methodology for Calculating the Seismic Response of Critical Structures; and (8) Reinforced Concrete Damage Modeling.

  12. Additive Similarity Trees

    ERIC Educational Resources Information Center

    Sattath, Shmuel; Tversky, Amos

    1977-01-01

    Tree representations of similarity data are investigated. Hierarchical clustering is critically examined, and a more general procedure, called the additive tree, is presented. The additive tree representation is then compared to multidimensional scaling. (Author/JKS)

  13. Synthesis of malhamensilipin A exploiting iterative epoxidation/chlorination: experimental and computational analysis of epoxide-derived chloronium ions† †Electronic supplementary information (ESI) available. CCDC 1470484 and 1470483. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc03012b Click here for additional data file. Click here for additional data file.

    PubMed Central

    Saska, J.; Lewis, W.

    2016-01-01

    We report a 12-step catalytic enantioselective formal synthesis of malhamensilipin A (3) and diastereoisomeric analogues from (E)-2-undecenal. The convergent synthesis relied upon iterative epoxidation and phosphorus(v)-mediated deoxydichlorination reactions as well a titanium-mediated epoxide-opening to construct the C11–C16 stereohexad. The latter transformation occurred with very high levels of stereoretention regardless of the C13 configuration of the parent epoxide, implicating anchimeric assistance of either the γ- or δ-chlorine atoms, and the formation of chloretanium or chlorolanium ions, respectively. A computational analysis of the chloronium ion intermediates provided support for the involvement of chlorolanium ions, whereas the potential chloretanium ions were found to be less likely intermediates on the basis of their greater carbocationic character.

  14. Impact of Classroom Computer Use on Computer Anxiety.

    ERIC Educational Resources Information Center

    Lambert, Matthew E.; And Others

    Increasing use of computer programs for undergraduate psychology education has raised concern over the impact of computer anxiety on educational performance. Additionally, some researchers have indicated that classroom computer use can exacerbate pre-existing computer anxiety. To evaluate the relationship between in-class computer use and computer…

  15. Comparison of cardiovascular response to combined static-dynamic effort, postprandial dynamic effort and dynamic effort alone in patients with chronic ischemic heart disease

    SciTech Connect

    Hung, J.; McKillip, J.; Savin, W.; Magder, S.; Kraus, R.; Houston, N.; Goris, M.; Haskell, W.; DeBusk, R.

    1982-06-01

    The cardiovascular responses to combined static-dynamic effort, postprandial dynamic effort and dynamic effort alone were evaluated by upright bicycle ergometry during equilibrium-gated blood pool scintigraphy in 24 men, mean age 59 +/- 8 years, with chronic ischemic heart disease. Combined static-dynamic effort and the postprandial state elicited a peak cardiovascular response similar to that of dynamic effort alone. Heart rate, intraarterial systolic and diastolic pressures, rate-pressure product and ejection fraction were similar for the three test conditions at the onset of ischemia and at peak effort. The prevalence and extent of exercise-induced ischemic left ventricular dysfunction, ST-segment depression, angina pectoris and ventricular ectopic activity were also similar during the three test conditions. Direct and indirect measurements of systolic and diastolic blood pressure were highly correlated. The onset of ischemic ST-segment depression and angina pectoris correlated as strongly with heart rate alone as with the rate-pressure product during all three test conditions. The cardiovascular response to combined static-dynamic effort and to postprandial dynamic effort becomes more similar to that of dynamic effort alone as dynamic effort reaches a symptom limit. If significant ischemic and arrhythmic abnormalities are absent during symptom-limited dynamic exercise testing, they are unlikely to appear during combined static-dynamic or postprandial dynamic effort.

  16. Teachable Agents and the Protege Effect: Increasing the Effort towards Learning

    ERIC Educational Resources Information Center

    Chase, Catherine C.; Chin, Doris B.; Oppezzo, Marily A.; Schwartz, Daniel L.

    2009-01-01

    Betty's Brain is a computer-based learning environment that capitalizes on the social aspects of learning. In Betty's Brain, students instruct a character called a Teachable Agent (TA) which can reason based on how it is taught. Two studies demonstrate the "protege effect": students make greater effort to learn for their TAs than they do…

  17. Database development in toxicogenomics: issues and efforts.

    PubMed Central

    Mattes, William B; Pettit, Syril D; Sansone, Susanna-Assunta; Bushel, Pierre R; Waters, Michael D

    2004-01-01

    The marriage of toxicology and genomics has created not only opportunities but also novel informatics challenges. As with the larger field of gene expression analysis, toxicogenomics faces the problems of probe annotation and data comparison across different array platforms. Toxicogenomics studies are generally built on standard toxicology studies generating biological end point data, and as such, one goal of toxicogenomics is to detect relationships between changes in gene expression and in those biological parameters. These challenges are best addressed through data collection into a well-designed toxicogenomics database. A successful publicly accessible toxicogenomics database will serve as a repository for data sharing and as a resource for analysis, data mining, and discussion. It will offer a vehicle for harmonizing nomenclature and analytical approaches and serve as a reference for regulatory organizations to evaluate toxicogenomics data submitted as part of registrations. Such a database would capture the experimental context of in vivo studies with great fidelity such that the dynamics of the dose response could be probed statistically with confidence. This review presents the collaborative efforts between the European Molecular Biology Laboratory-European Bioinformatics Institute ArrayExpress, the International Life Sciences Institute Health and Environmental Science Institute, and the National Institute of Environmental Health Sciences National Center for Toxigenomics Chemical Effects in Biological Systems knowledge base. The goal of this collaboration is to establish public infrastructure on an international scale and examine other developments aimed at establishing toxicogenomics databases. In this review we discuss several issues common to such databases: the requirement for identifying minimal descriptors to represent the experiment, the demand for standardizing data storage and exchange formats, the challenge of creating standardized nomenclature

  18. VLTI-UT vibrations effort and performances

    NASA Astrophysics Data System (ADS)

    Poupar, Sébastien; Haguenauer, Pierre; Alonso, Jaime; Schuhler, Nicolas; Henriquez, Juan-Pablo; Berger, Jean-Philippe; Bourget, Pierre; Brillant, Stephane; Castillo, Roberto; Gitton, Philippe; Gonte, Frederic; Di Lieto, Nicola; Lizon, Jean-Louis; Merand, Antoine; Woillez, Julien

    2014-07-01

    The ESO Very Large Telescope Interferometer (VLTI) using the Unit Telescope (UT) was strongly affected by vibrations since the first observations. Investigation by ESO on that subject had started in 2007, with a considerable effort since mid 2008. An important number of investigations on various sub-systems (On telescope: Guiding, Passive supports, Train Coude, insulation of electronics cabinets; On Instruments: dedicated campaign on each instruments with a special attention on the ones equipped with Close Cycle Cooler) were realized. Vibrations were not only recorded and analyzed using the usual accelerometers but also using on use sub-systems as InfRared Image Sensor (IRIS) and Multiple Applications Curvature Adaptive Optics (MACAO) and using a specific tool developed for vibrations measurements Mirror vibrAtion Metrology systeM for the Unit Telescope (MAMMUT). Those tools and systems have been used in order to improve the knowledge on telescope by finding sources. The sources whenever it was possible were damped. As known for years, instruments are still the principal sources of vibrations, for the majority of the UT. A special test in which 2 UTs instruments were completely shut down was realized to determine the minimum Optical Path Length (OPL) achievable. Vibrations is now a part of the instruments interface document and during the installation of any new instrument (KMOS) or system (AOF) a test campaign is realized. As a result some modifications (damping of CCC) can be asked in case of non-compliance. To ensure good operational conditions, levels of vibrations are regularly recorded to control any environmental change.

  19. Holographic data storage: rebirthing a commercialization effort

    NASA Astrophysics Data System (ADS)

    Anderson, Ken; Ayres, Mark; Sissom, Brad; Askham, Fred

    2014-02-01

    The realization of a commercial holographic data storage device has remained elusive for many decades. The most recent efforts were by InPhase Technologies between 2001 and 2009 resulting in 52 functioning prototypes capable of 300GB/disk and 20MB/s transfer rates. Despite being the world's first fully functional holographic drives, the primary competitor to holographic archive storage at that time, LTO, had already achieved 800GB and 120MB/in 2008; and by 2010, LTO had achieved 1.5TB and 140MB/s. This left InPhase at a competitive disadvantage to LTO archive solutions despite other strengths such as robustness, random access, and longer-term archive lifetime. Looking into the future, holographic data storage must be highly competitive with tape in three critical areas: cost/TB, capacity/footprint, and transfer rate. If this can be achieved, holographic data storage would become a superior solution given the low latencies and overall robustness to propel it into being the archive storage front-runner. New technology advancements by Akonia Holographics have enabled the potential for ultra-high capacity holographic storage devices that are capable of world record bit densities of over 2Tbit/in2, 200-300MB/s transfer rates, and a media cost less than $10/TB in the next 5 years. A demonstration platform based on these new advances has been designed and is currently being built by Akonia to progressively demonstrate bit densities of 2Tb/in2, 4Tb/in2, and 8Tb/in2 over the next year.

  20. Would You Recommend Your Institution's Effort-Reporting Process to Others? Determining Best Practices in Effort-Reporting Compliance

    ERIC Educational Resources Information Center

    Whitaker, Ashley E.

    2015-01-01

    Effort-reporting compliance at higher education institutions was examined to discern best practices from those that would recommend their effort-reporting process. Data were derived from a survey of effort administrators--the research administrators responsible for the effort-reporting compliance program at their respective higher education…

  1. Polyimide processing additives

    NASA Technical Reports Server (NTRS)

    Pratt, J. R.; St. Clair, T. L.; Burks, H. D.; Stoakley, D. M.

    1987-01-01

    A method has been found for enhancing the melt flow of thermoplastic polyimides during processing. A high molecular weight 422 copoly(amic acid) or copolyimide was fused with approximately 0.05 to 5 pct by weight of a low molecular weight amic acid or imide additive, and this melt was studied by capillary rheometry. Excellent flow and improved composite properties on graphite resulted from the addition of a PMDA-aniline additive to LARC-TPI. Solution viscosity studies imply that amic acid additives temporarily lower molecular weight and, hence, enlarge the processing window. Thus, compositions containing the additive have a lower melt viscosity for a longer time than those unmodified.

  2. [Food additives and healthiness].

    PubMed

    Heinonen, Marina

    2014-01-01

    Additives are used for improving food structure or preventing its spoilage, for example. Many substances used as additives are also naturally present in food. The safety of additives is evaluated according to commonly agreed principles. If high concentrations of an additive cause adverse health effects for humans, a limit of acceptable daily intake (ADI) is set for it. An additive is a risk only when ADI is exceeded. The healthiness of food is measured on the basis of nutrient density and scientifically proven effects.

  3. Motor effort alters changes of mind in sensorimotor decision making.

    PubMed

    Burk, Diana; Ingram, James N; Franklin, David W; Shadlen, Michael N; Wolpert, Daniel M

    2014-01-01

    After committing to an action, a decision-maker can change their mind to revise the action. Such changes of mind can even occur when the stream of information that led to the action is curtailed at movement onset. This is explained by the time delays in sensory processing and motor planning which lead to a component at the end of the sensory stream that can only be processed after initiation. Such post-initiation processing can explain the pattern of changes of mind by asserting an accumulation of additional evidence to a criterion level, termed change-of-mind bound. Here we test the hypothesis that physical effort associated with the movement required to change one's mind affects the level of the change-of-mind bound and the time for post-initiation deliberation. We varied the effort required to change from one choice target to another in a reaching movement by varying the geometry of the choice targets or by applying a force field between the targets. We show that there is a reduction in the frequency of change of mind when the separation of the choice targets would require a larger excursion of the hand from the initial to the opposite choice. The reduction is best explained by an increase in the evidence required for changes of mind and a reduced time period of integration after the initial decision. Thus the criteria to revise an initial choice is sensitive to energetic costs.

  4. [Limitation of the therapeutic effort in pediatric intensive care].

    PubMed

    Morales, V Gonzalo

    2015-01-01

    Pediatric intensive care is a relatively new medical specialty, which has experienced significant technological advances in recent years. These developments have led to a prolongation of the dying process, with additional suffering for patients and their families, creating complex situations, and often causing a painful life extension. The term, limitation of the therapeutic effort refers to the adequacy and/or proportionality of the treatment, trying to avoid obstinacy and futility. The English literature does not talk about limitation of treatments, but instead the terms, withholding or withdrawal of life-sustaining treatment, are used. The removal or the non-installation of certain life support measures and the absence of CPR are the types of limitation most used. Also, there is evidence of insufficient medical training in bioethics, which is essential, as most doctors in the PICU discuss and make decisions regarding the end of life without the opinion of bioethicists. This article attempts to review the current status of knowledge concerning the limitation of therapeutic efforts to support pediatric clinical work.

  5. Hiding effort to gain a competitive advantage: Evidence from China.

    PubMed

    Zhao, Li; Heyman, Gail D

    2016-06-06

    Previous studies with Western populations have shown that adolescents' tendency to downplay their academic effort is affected by two kinds of motives: ability-related motives (e.g., to appear competent) and social approval motives (e.g., to be popular). In this research, we test for the presence of additional competition-related motives in China, a culture placing strong emphasis on academic competition. Study 1 (N = 150) showed that, in response to a scenario in which a hard-working high-school junior hid effort from classmates, the most highly endorsed explanation was "to influence others to work less hard to maintain a competitive advantage." Study 2 (N = 174) revealed that competition-related explanations were endorsed relatively more often when the speaker and audience had similar academic rankings. This tendency was most evident when both speaker and audience were top performers, and when this was the case, participants' desire to demonstrate superiority over others was a positive predictor of endorsement of competition-related motives. Study 3 (N = 137) verified that competition-related motives were more strongly endorsed among Chinese participants than U.S.

  6. Computers + Student Activities Handbook.

    ERIC Educational Resources Information Center

    Masie, Elliott; Stein, Michele

    Designed to provide schools with the tools to start utilizing computers for student activity programs without additional expenditures, this handbook provides beginning computer users with suggestions and ideas for using computers in such activities as drama clubs, yearbooks, newspapers, activity calendars, accounting programs, room utilization,…

  7. Site Protection Efforts at the AURA Observatory in Chile

    NASA Astrophysics Data System (ADS)

    Smith, R. Chris; Sanhueza, Pedro; Smith, Malcolm G.

    2016-10-01

    The AURA Observatory site in northern Chile, which includes Cerro Tololo and Cerro Pachon, has been operational for over 50 years now, facing a variety of challenges to its long-term future. The site now hosts over 20 operational telescopes, ranging from small projects with 0.4m telescopes to the Blanco 4m, the SOAR 4.1m, and the 8m Gemini-South telescopes. In addition, we have recently begun the construction of the Large Synoptic Survey Telescope (LSST) on the summit of Cerro Pachon. We summarize our efforts over the past 20-30 years to highlight the importance of site protection through education and public outreach as well as through more recent promotion of IDA certifications in the region and support for the World Heritage initiatives described by others in this conference.

  8. A Coordinated Effort to Address Space Weather and Environment Needs

    NASA Technical Reports Server (NTRS)

    Minow, Joe; Spann, James F.; Edward, David L.; Burns, Howard D.; Gallagher, Dennis; Xapos, Mike; DeGroh, Kim

    2010-01-01

    The growing need for coordination of the many aspects of space environments is directly related to our increasing dependence on space assets. An obvious result is that there is a need for a coordinated effort to organize and make accessible the increasing number of space environment products that include space environment models and observations, material testing, and forecasting tools. This paper outlines a concept to establish a NASA-level Applied Spaceflight Environments (ASE) office that will provide coordination and funding for sustained multi-program support in three technical areas; (1) natural environments characterization and modeling, (2) environmental effects on materials and systems, (3) and operational and forecasting space environments modeling. Additionally the ASE office will serve as an entry point of contact for external users who wish to take advantage of data and assets associated with space environments, including space weather.

  9. It takes some effort. How minimal physical effort reduces consumption volume.

    PubMed

    Brunner, Thomas A

    2013-12-01

    Plenty of studies have demonstrated that effort influences food choice. However, few have been conducted to analyze the effect of effort on consumption volume. Moreover, the few studies that have measured consumption volume all have strong limitations. The goal of the present paper is to disentangle confounding variables in earlier research and to rule out various alternative explanations. In a tasting setting focusing on snacking behavior, either unwrapping a food product or grabbing it with sugar tongs was enough to significantly reduce consumption, regardless of whether an unhealthy or healthy food item was used. Hardly any cognitive resources seem to be necessary for the effect to occur, as cognitive load did not affect the findings. In light of obesity being a pressing concern, these findings might be valuable for individuals as well as for the food industry.

  10. Tailoring hospital marketing efforts to physicians' needs.

    PubMed

    Mackay, J M; Lamb, C W

    1988-12-01

    Marketing has become widely recognized as an important component of hospital management (Kotler and Clarke 1987; Ludke, Curry, and Saywell 1983). Physicians are becoming recognized as an important target market that warrants more marketing attention than it has received in the past (Super 1987; Wotruba, Haas, and Hartman 1982). Some experts predict that hospitals will begin focusing more marketing attention on physicians and less on consumers (Super 1986). Much of this attention is likely to take the form of practice management assistance, such as computer-based information system support or consulting services. The survey results reported here are illustrative only of how one hospital addressed the problem of physician need assessment. Other potential target markets include physicians who admit patients only to competitor hospitals and physicians who admit to multiple hospitals. The market might be segmented by individual versus group practice, area of specialization, or possibly even physician practice life cycle stage (Wotruba, Haas, and Hartman 1982). The questions included on the survey and the survey format are likely to be situation-specific. The key is the process, not the procedure. It is important for hospital marketers to recognize that practice management assistance needs will vary among markets (Jensen 1987). Therefore, hospitals must carefully identify their target physician market(s) and survey them about their specific needs before developing and implementing new physician marketing programs. Only then can they be reasonably confident that their marketing programs match their customers' needs.

  11. Characterization of Metal Powders Used for Additive Manufacturing

    PubMed Central

    Slotwinski, JA; Garboczi, EJ; Stutzman, PE; Ferraris, CF; Watson, SS; Peltz, MA

    2014-01-01

    Additive manufacturing (AM) techniques1 can produce complex, high-value metal parts, with potential applications as critical parts, such as those found in aerospace components. The production of AM parts with consistent and predictable properties requires input materials (e.g., metal powders) with known and repeatable characteristics, which in turn requires standardized measurement methods for powder properties. First, based on our previous work, we assess the applicability of current standardized methods for powder characterization for metal AM powders. Then we present the results of systematic studies carried out on two different powder materials used for additive manufacturing: stainless steel and cobalt-chrome. The characterization of these powders is important in NIST efforts to develop appropriate measurements and standards for additive materials and to document the property of powders used in a NIST-led additive manufacturing material round robin. An extensive array of characterization techniques was applied to these two powders, in both virgin and recycled states. The physical techniques included laser diffraction particle size analysis, X-ray computed tomography for size and shape analysis, and optical and scanning electron microscopy. Techniques sensitive to structure and chemistry, including X-ray diffraction, energy dispersive analytical X-ray analysis using the X-rays generated during scanning electron microscopy, and X-Ray photoelectron spectroscopy were also employed. The results of these analyses show how virgin powder changes after being exposed to and recycled from one or more Direct Metal Laser Sintering (DMLS) additive manufacturing build cycles. In addition, these findings can give insight into the actual additive manufacturing process. PMID:26601040

  12. Characterization of Metal Powders Used for Additive Manufacturing.

    PubMed

    Slotwinski, J A; Garboczi, E J; Stutzman, P E; Ferraris, C F; Watson, S S; Peltz, M A

    2014-01-01

    Additive manufacturing (AM) techniques can produce complex, high-value metal parts, with potential applications as critical parts, such as those found in aerospace components. The production of AM parts with consistent and predictable properties requires input materials (e.g., metal powders) with known and repeatable characteristics, which in turn requires standardized measurement methods for powder properties. First, based on our previous work, we assess the applicability of current standardized methods for powder characterization for metal AM powders. Then we present the results of systematic studies carried out on two different powder materials used for additive manufacturing: stainless steel and cobalt-chrome. The characterization of these powders is important in NIST efforts to develop appropriate measurements and standards for additive materials and to document the property of powders used in a NIST-led additive manufacturing material round robin. An extensive array of characterization techniques was applied to these two powders, in both virgin and recycled states. The physical techniques included laser diffraction particle size analysis, X-ray computed tomography for size and shape analysis, and optical and scanning electron microscopy. Techniques sensitive to structure and chemistry, including X-ray diffraction, energy dispersive analytical X-ray analysis using the X-rays generated during scanning electron microscopy, and X-Ray photoelectron spectroscopy were also employed. The results of these analyses show how virgin powder changes after being exposed to and recycled from one or more Direct Metal Laser Sintering (DMLS) additive manufacturing build cycles. In addition, these findings can give insight into the actual additive manufacturing process.

  13. Computers and Computer Resources.

    ERIC Educational Resources Information Center

    Bitter, Gary

    1980-01-01

    This resource directory provides brief evaluative descriptions of six popular home computers and lists selected sources of educational software, computer books, and magazines. For a related article on microcomputers in the schools, see p53-58 of this journal issue. (SJL)

  14. Effort-Based Decision Making: A Novel Approach for Assessing Motivation in Schizophrenia

    PubMed Central

    Green, Michael F.; Horan, William P.; Barch, Deanna M.; Gold, James M.

    2015-01-01

    Because negative symptoms, including motivational deficits, are a critical unmet need in schizophrenia, there are many ongoing efforts to develop new pharmacological and psychosocial interventions for these impairments. A common challenge of these studies involves how to evaluate and select optimal endpoints. Currently, all studies of negative symptoms in schizophrenia depend on ratings from clinician-conducted interviews. Effort-based decision-making tasks may provide a more objective, and perhaps more sensitive, endpoint for trials of motivational negative symptoms. These tasks assess how much effort a person is willing to exert for a given level of reward. This area has been well-studied with animal models of effort and motivation, and effort-based decision-making tasks have been adapted for use in humans. Very recently, several studies have examined physical and cognitive types of effort-based decision-making tasks in cross-sectional studies of schizophrenia, providing evidence for effort-related impairment in this illness. This article covers the theoretical background on effort-based decision-making tasks to provide a context for the subsequent articles in this theme section. In addition, we review the existing literature of studies using these tasks in schizophrenia, consider some practical challenges in adapting them for use in clinical trials in schizophrenia, and discuss interpretive challenges that are central to these types of tasks. PMID:26089350

  15. Effort-Based Decision Making: A Novel Approach for Assessing Motivation in Schizophrenia.

    PubMed

    Green, Michael F; Horan, William P; Barch, Deanna M; Gold, James M

    2015-09-01

    Because negative symptoms, including motivational deficits, are a critical unmet need in schizophrenia, there are many ongoing efforts to develop new pharmacological and psychosocial interventions for these impairments. A common challenge of these studies involves how to evaluate and select optimal endpoints. Currently, all studies of negative symptoms in schizophrenia depend on ratings from clinician-conducted interviews. Effort-based decision-making tasks may provide a more objective, and perhaps more sensitive, endpoint for trials of motivational negative symptoms. These tasks assess how much effort a person is willing to exert for a given level of reward. This area has been well-studied with animal models of effort and motivation, and effort-based decision-making tasks have been adapted for use in humans. Very recently, several studies have examined physical and cognitive types of effort-based decision-making tasks in cross-sectional studies of schizophrenia, providing evidence for effort-related impairment in this illness. This article covers the theoretical background on effort-based decision-making tasks to provide a context for the subsequent articles in this theme section. In addition, we review the existing literature of studies using these tasks in schizophrenia, consider some practical challenges in adapting them for use in clinical trials in schizophrenia, and discuss interpretive challenges that are central to these types of tasks.

  16. Physical, emotional, and cognitive effort discounting in gain and loss situations.

    PubMed

    Nishiyama, Ryoji

    2016-04-01

    Evidence suggests that factors associated with obtaining a reward, such as the probability of receiving it, or temporal delays, could influence the reward's subjective value. Several studies have suggested that increasing the effort required decreases the subjective value of a reward. Nevertheless, the nature of effort that results in discounting, discounting in a loss situation, and individual consistency in effort aversion across different types of effort have all remained unclear. Therefore, the present study examined whether physical, emotional, and cognitive efforts induce discounting of subjective reward value under two hypothetical situations. In the gain situation, participants made a choice about engaging in effortful work to obtain a reward, whereas in the loss situation they paid a reward to another person to do the work. The results demonstrated that increasing physical, emotional, and cognitive effort caused discounting of the subjective reward value in both situations. Additionally, the results suggested a relatively high degree of individual consistency in effort aversion in each situation, and a moderate degree of consistency across the two situations.

  17. Light multinary computing

    NASA Astrophysics Data System (ADS)

    Arago, Jaime

    2012-11-01

    Next-generation optical communication and optical computing imply an evolution from binary to multinary computing. Light multinary computing encodes data using pulses of light components in higher orders than binary and processes it using truth tables larger than Boolean ones. This results in lesser encoded data that can be processed at faster speeds. We use a general-purpose optical transistor as the building block to develop the main computing units for counting, distributing, storing, and logically operating the arithmetic addition of two bytes of base-10 data. Currently available optical switching technologies can be used to physically implement light multinary computing to achieve ultra-high speed communication and computing.

  18. Taking the Time to Improve the Validity of Low-Stakes Tests: The Effort-Monitoring CBT

    ERIC Educational Resources Information Center

    Wise, Steven L.; Bhola, Dennison S.; Yang, Sheng-Ta

    2006-01-01

    The attractiveness of computer-based tests (CBTs) is due largely to their capability to expand the ways we conduct testing. A relatively unexplored application, however, is actively using the computer to reduce construct-irrelevant variance while a test is being administered. This investigation introduces the effort-monitoring CBT, in which the…

  19. Additional Security Considerations for Grid Management

    NASA Technical Reports Server (NTRS)

    Eidson, Thomas M.

    2003-01-01

    The use of Grid computing environments is growing in popularity. A Grid computing environment is primarily a wide area network that encompasses multiple local area networks, where some of the local area networks are managed by different organizations. A Grid computing environment also includes common interfaces for distributed computing software so that the heterogeneous set of machines that make up the Grid can be used more easily. The other key feature of a Grid is that the distributed computing software includes appropriate security technology. The focus of most Grid software is on the security involved with application execution, file transfers, and other remote computing procedures. However, there are other important security issues related to the management of a Grid and the users who use that Grid. This note discusses these additional security issues and makes several suggestions as how they can be managed.

  20. MACCS2 development and verification efforts

    SciTech Connect

    Young, M.; Chanin, D.

    1997-03-01

    MACCS2 represents a major enhancement of the capabilities of its predecessor MACCS, the MELCOR Accident Consequence Code System. MACCS, released in 1987, was developed to estimate the potential impacts to the surrounding public of severe accidents at nuclear power plants. The principal phenomena considered in MACCS/MACCS2 are atmospheric transport and deposition under time-variant meteorology, short-term and long-term mitigative actions and exposure pathways, deterministic and stochastic health effects, and economic costs. MACCS2 was developed as a general-purpose analytical tool applicable to diverse reactor and nonreactor facilities. The MACCS2 package includes three primary enhancements: (1) a more flexible emergency response model, (2) an expanded library of radionuclides, and (3) a semidynamic food-chain model. In addition, errors that had been identified in MACCS version1.5.11.1 were corrected, including an error that prevented the code from providing intermediate-phase results. MACCS2 version 1.10 beta test was released to the beta-test group in May, 1995. In addition, the University of New Mexico (UNM) has completed an independent verification study of the code package. Since the beta-test release of MACCS2 version 1.10, a number of minor errors have been identified and corrected, and a number of enhancements have been added to the code package. The code enhancements added since the beta-test release of version 1.10 include: (1) an option to allow the user to input the {sigma}{sub y} and {sigma}{sub z} plume expansion parameters in a table-lookup form for incremental downwind distances, (2) an option to define different initial dimensions for up to four segments of a release, (3) an enhancement to the COMIDA2 food-chain model preprocessor to allow the user to supply externally calculated tables of tritium food-chain dose per unit deposition on farmland to support analyses of tritium releases, and (4) the capability to calculate direction-dependent doses.

  1. Thyroid iodide efflux: a team effort?

    PubMed

    Fong, Peying

    2011-12-15

    The thyroid hormones thyroxine (T(4)) and triiodothyronine (T(3)) play key roles in regulating development, growth and metabolism in pre- and postnatal life. Iodide (I(-)) is an essential component of the thyroid hormones and is accumulated avidly by the thyroid gland. The rarity of elemental iodine and I(-) in the environment challenges the thyroid to orchestrate a remarkable series of transport processes that ultimately ensure sufficient levels for hormone synthesis. In addition to actively extracting circulating I(-), thyroid follicular epithelial cells must also translocate I(-) into a central intrafollicular compartment, where thyroglobulin is iodinated to form the protein precursor to T(4) and T(3). In the last decade, several bodies of evidence render questionable the notion that I(-) exits thyrocytes solely via the Cl(-)/I(-) exchanger Pendrin (SLC26A4), therefore necessitating reconsideration of several other candidate I(-) conduits: the Cl(-)/H(+) antiporter, CLC-5, the cystic fibrosis transmembrane conductance regulator (CFTR) and the sodium monocarboxylic acid transporter (SMCT1).

  2. The addition of computer simulated noise to investigate radiation dose and image quality in images with spatial correlation of statistical noise: an example application to X-ray CT of the brain.

    PubMed

    Britten, A J; Crotty, M; Kiremidjian, H; Grundy, A; Adam, E J

    2004-04-01

    This study validates a method to add spatially correlated statistical noise to an image, applied to transaxial X-ray CT images of the head to simulate exposure reduction by up to 50%. 23 patients undergoing routine head CT had three additional slices acquired for validation purposes, two at the same clinical 420 mAs exposure and one at 300 mAs. Images at the level of the cerebrospinal fluid filled ventricles gave readings of noise from a single image, with subtraction of image pairs to obtain noise readings from non-uniform tissue regions. The spatial correlation of the noise was determined and added to the acquired 420 mAs image to simulate images at 340 mAs, 300 mAs, 260 mAs and 210 mAs. Two radiologists assessed the images, finding little difference between the 300 mAs simulated and acquired images. The presence of periventricular low density lesions (PVLD) was used as an example of the effect of simulated dose reduction on diagnostic accuracy, and visualization of the internal capsule was used as a measure of image quality. Diagnostic accuracy for the diagnosis of PVLD did not fall significantly even down to 210 mAs, though visualization of the internal capsule was poorer at lower exposure. Further work is needed to investigate means of measuring statistical noise without the need for uniform tissue areas, or image pairs. This technique has been shown to allow sufficiently accurate simulation of dose reduction and image quality degradation, even when the statistical noise is spatially correlated.

  3. Parallel computing in enterprise modeling.

    SciTech Connect

    Goldsby, Michael E.; Armstrong, Robert C.; Shneider, Max S.; Vanderveen, Keith; Ray, Jaideep; Heath, Zach; Allan, Benjamin A.

    2008-08-01

    This report presents the results of our efforts to apply high-performance computing to entity-based simulations with a multi-use plugin for parallel computing. We use the term 'Entity-based simulation' to describe a class of simulation which includes both discrete event simulation and agent based simulation. What simulations of this class share, and what differs from more traditional models, is that the result sought is emergent from a large number of contributing entities. Logistic, economic and social simulations are members of this class where things or people are organized or self-organize to produce a solution. Entity-based problems never have an a priori ergodic principle that will greatly simplify calculations. Because the results of entity-based simulations can only be realized at scale, scalable computing is de rigueur for large problems. Having said that, the absence of a spatial organizing principal makes the decomposition of the problem onto processors problematic. In addition, practitioners in this domain commonly use the Java programming language which presents its own problems in a high-performance setting. The plugin we have developed, called the Parallel Particle Data Model, overcomes both of these obstacles and is now being used by two Sandia frameworks: the Decision Analysis Center, and the Seldon social simulation facility. While the ability to engage U.S.-sized problems is now available to the Decision Analysis Center, this plugin is central to the success of Seldon. Because Seldon relies on computationally intensive cognitive sub-models, this work is necessary to achieve the scale necessary for realistic results. With the recent upheavals in the financial markets, and the inscrutability of terrorist activity, this simulation domain will likely need a capability with ever greater fidelity. High-performance computing will play an important part in enabling that greater fidelity.

  4. Computational methods in metabolic engineering for strain design.

    PubMed

    Long, Matthew R; Ong, Wai Kit; Reed, Jennifer L

    2015-08-01

    Metabolic engineering uses genetic approaches to control microbial metabolism to produce desired compounds. Computational tools can identify new biological routes to chemicals and the changes needed in host metabolism to improve chemical production. Recent computational efforts have focused on exploring what compounds can be made biologically using native, heterologous, and/or enzymes with broad specificity. Additionally, computational methods have been developed to suggest different types of genetic modifications (e.g. gene deletion/addition or up/down regulation), as well as suggest strategies meeting different criteria (e.g. high yield, high productivity, or substrate co-utilization). Strategies to improve the runtime performances have also been developed, which allow for more complex metabolic engineering strategies to be identified. Future incorporation of kinetic considerations will further improve strain design algorithms.

  5. Polyimide processing additives

    NASA Technical Reports Server (NTRS)

    Fletcher, James C. (Inventor); Pratt, J. Richard (Inventor); St.clair, Terry L. (Inventor); Stoakley, Diane M. (Inventor); Burks, Harold D. (Inventor)

    1992-01-01

    A process for preparing polyimides having enhanced melt flow properties is described. The process consists of heating a mixture of a high molecular weight poly-(amic acid) or polyimide with a low molecular weight amic acid or imide additive in the range of 0.05 to 15 percent by weight of additive. The polyimide powders so obtained show improved processability, as evidenced by lower melt viscosity by capillary rheometry. Likewise, films prepared from mixtures of polymers with additives show improved processability with earlier onset of stretching by TMA.

  6. Polyimide processing additives

    NASA Technical Reports Server (NTRS)

    Pratt, J. Richard (Inventor); St.clair, Terry L. (Inventor); Stoakley, Diane M. (Inventor); Burks, Harold D. (Inventor)

    1993-01-01

    A process for preparing polyimides having enhanced melt flow properties is described. The process consists of heating a mixture of a high molecular weight poly-(amic acid) or polyimide with a low molecular weight amic acid or imide additive in the range of 0.05 to 15 percent by weight of the additive. The polyimide powders so obtained show improved processability, as evidenced by lower melt viscosity by capillary rheometry. Likewise, films prepared from mixtures of polymers with additives show improved processability with earlier onset of stretching by TMA.

  7. 7 CFR 622.31 - Basic planning efforts.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Basic planning efforts. 622.31 Section 622.31..., DEPARTMENT OF AGRICULTURE WATER RESOURCES WATERSHED PROJECTS Planning § 622.31 Basic planning efforts. Upon... the need for planning effort. Once planning is authorized by the Chief of NRCS, a watershed...

  8. Measuring Developmental Levels of Understanding of Ability and Effort.

    ERIC Educational Resources Information Center

    Miller, Arden T.; Nicholls, John G.

    Discussed are research methods used to measure developmental changes in children's reasoning about ability. While adults generally differentiate ability, effort, luck, and task difficulty as causes for success and failure, children progressively think that effort or outcome is ability (level 1), that effort is the cause of performance outcomes…

  9. 7 CFR 622.31 - Basic planning efforts.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., DEPARTMENT OF AGRICULTURE WATER RESOURCES WATERSHED PROJECTS Planning § 622.31 Basic planning efforts. Upon... 7 Agriculture 6 2011-01-01 2011-01-01 false Basic planning efforts. 622.31 Section 622.31... the need for planning effort. Once planning is authorized by the Chief of NRCS, a watershed...

  10. Assessing Organizational Efforts to Mobilize Research Knowledge in Education

    ERIC Educational Resources Information Center

    Qi, Jie; Levin, Benjamin

    2013-01-01

    This paper presents a framework for evaluating efforts by organizations to share research as exemplified on their websites, then reports the result of an evaluation of these efforts in 100 organizations. The result shows that the overall research sharing efforts of these organizations are modest and not well aligned to evidence on effective…

  11. 45 CFR 152.39 - Maintenance of effort.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Maintenance of effort. 152.39 Section 152.39... of effort. (a) General. A State that enters into a contract with HHS under this part must demonstrate... the contract is entered. (b) Failure to maintain efforts. In situations where a State enters into...

  12. 48 CFR 2052.216-70 - Level of effort.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Level of effort. 2052.216... Level of effort. As prescribed at 2016.307-70(a) the contracting officer shall insert the following..., time and materials, or labor hours basis. Level of Effort (JAN 1993) The NRC's estimate of the...

  13. 20 CFR 327.15 - Reasonable efforts to obtain work.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Reasonable efforts to obtain work. 327.15... INSURANCE ACT AVAILABLE FOR WORK § 327.15 Reasonable efforts to obtain work. (a) Requirement. A claimant may... efforts to obtain work which he professes to be willing to accept and perform, unless he has...

  14. 24 CFR 245.205 - Efforts to obtain assistance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Efforts to obtain assistance. 245... AUTHORITIES TENANT PARTICIPATION IN MULTIFAMILY HOUSING PROJECTS Efforts To Obtain Assistance § 245.205 Efforts to obtain assistance. (a) Mortgagors subject to the requirements of this subpart shall...

  15. 42 CFR 441.180 - Maintenance of effort: General rule.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Maintenance of effort: General rule. 441.180... § 441.180 Maintenance of effort: General rule. FFP is available only if the State maintains fiscal effort as prescribed under this subpart....

  16. 48 CFR 1511.011-73 - Level of effort.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Level of effort. 1511.011... ACQUISITION PLANNING DESCRIBING AGENCY NEEDS 1511.011-73 Level of effort. The Contracting Officer shall insert the clause at 1552.211-73, Level of Effort, in term form contracts....

  17. 48 CFR 1331.205-70 - Duplication of effort.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Duplication of effort....205-70 Duplication of effort. The Department will not pay any costs for work that is duplicative of..., Duplication of Effort, in all cost-reimbursement, time and materials, and labor hour solicitations...

  18. 15 CFR 930.114 - Secretarial mediation efforts.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Secretarial mediation efforts. 930.114... Secretarial mediation efforts. (a) Following the close of the hearing, the hearing officer shall transmit the... set for the mediation conference. (b) Secretarial mediation efforts shall last only so long as...

  19. Validated Predictions of Metabolic Energy Consumption for Submaximal Effort Movement

    PubMed Central

    Tsianos, George A.; MacFadden, Lisa N.

    2016-01-01

    Physical performance emerges from complex interactions among many physiological systems that are largely driven by the metabolic energy demanded. Quantifying metabolic demand is an essential step for revealing the many mechanisms of physical performance decrement, but accurate predictive models do not exist. The goal of this study was to investigate if a recently developed model of muscle energetics and force could be extended to reproduce the kinematics, kinetics, and metabolic demand of submaximal effort movement. Upright dynamic knee extension against various levels of ergometer load was simulated. Task energetics were estimated by combining the model of muscle contraction with validated models of lower limb musculotendon paths and segment dynamics. A genetic algorithm was used to compute the muscle excitations that reproduced the movement with the lowest energetic cost, which was determined to be an appropriate criterion for this task. Model predictions of oxygen uptake rate (VO2) were well within experimental variability for the range over which the model parameters were confidently known. The model's accurate estimates of metabolic demand make it useful for assessing the likelihood and severity of physical performance decrement for a given task as well as investigating underlying physiologic mechanisms. PMID:27248429

  20. Closeout of JOYO-1 Specimen Fabrication Efforts

    SciTech Connect

    ME Petrichek; JL Bump; RF Luther

    2005-10-31

    Fabrication was well under way for the JOYO biaxial creep and tensile specimens when the NR Space program was canceled. Tubes of FS-85, ASTAR-811C, and T-111 for biaxial creep specimens had been drawn at True Tube (Paso Robles, CA), while tubes of Mo-47.5 Re were being drawn at Rhenium Alloys (Cleveland, OH). The Mo-47.5 Re tubes are now approximately 95% complete. Their fabrication and the quantities produced will be documented at a later date. End cap material for FS-85, ASTAR-811C, and T-111 had been swaged at Pittsburgh Materials Technology, Inc. (PMTI) (Large, PA) and machined at Vangura (Clairton, PA). Cutting of tubes, pickling, annealing, and laser engraving were in process at PMTI. Several biaxial creep specimen sets of FS-85, ASTAR-811C, and T-111 had already been sent to Pacific Northwest National Laboratory (PNNL) for weld development. In addition, tensile specimens of FS-85, ASTAR-811C, T-111, and Mo-47.5 Re had been machined at Kin-Tech (North Huntington, PA). Actual machining of the other specimen types had not been initiated. Flowcharts 1-3 detail the major processing steps each piece of material has experienced. A more detailed description of processing will be provided in a separate document [B-MT(SRME)-51]. Table 1 lists the in-process materials and finished specimens. Also included are current metallurgical condition of these materials and specimens. The available chemical analyses for these alloys at various points in the process are provided in Table 2.

  1. Environmental gap analysis to prioritize conservation efforts in eastern Africa.

    PubMed

    van Breugel, Paulo; Kindt, Roeland; Barnekow Lillesø, Jens-Peter; van Breugel, Michiel

    2015-01-01

    Countries in eastern Africa have set aside significant proportions of their land for protection. But are these areas representative of the diverse range of species and habitats found in the region? And do conservation efforts include areas where the state of biodiversity is likely to deteriorate without further interventions? Various studies have addressed these questions at global and continental scales. However, meaningful conservation decisions are required at finer geographical scales. To operate more effectively at the national level, finer scale baseline data on species and on higher levels of biological organization such as the eco-regions are required, among other factors. Here we adopted a recently developed high-resolution potential natural vegetation (PNV) map for eastern Africa as a baseline to more effectively identify conservation priorities. We examined how well different potential natural vegetations (PNVs) are represented in the protected area (PA) network of eastern Africa and used a multivariate environmental similarity index to evaluate biases in PA versus PNV coverage. We additionally overlaid data of anthropogenic factors that potentially influence the natural vegetation to assess the level of threat to different PNVs. Our results indicate substantial differences in the conservation status of PNVs. In addition, particular PNVs in which biodiversity protection and ecological functions are at risk due to human influences are revealed. The data and approach presented here provide a step forward in developing more transparent and better informed translation from global priorities to regional or national implementation in eastern Africa, and are valid for other geographic regions.

  2. In-Vessel Retention - Recent Efforts and Future Needs

    SciTech Connect

    J. L. Rempe

    2004-10-01

    In-vessel retention (IVR) of core melt is a key severe accident management strategy adopted by some operating nuclear power plants and proposed for some advanced light water reactors (ALWRs). If there were inadequate cooling during a reactor accident, a significant amount of core material could become molten and relocate to the lower head of the reactor vessel, as happened in the Three Mile Island Unit 2 (TMI-2) accident. If it is possible to ensure that the vessel head remains intact so that relocated core materials are retained within the vessel, the enhanced safety associated with these plants can reduce concerns about containment failure and associated risk. However, it is not clear that the external reactor vessel cooling (ERVC) proposed for existing and some advanced reactors would provide sufficient heat removal for higher-power reactors (up to 1400 MWe) without additional enhancements. This paper summarizes recent efforts to enhance IVR and identifies additional needs to demonstrate that there is sufficient margin for successful IVR in high power reactors.

  3. Environmental Gap Analysis to Prioritize Conservation Efforts in Eastern Africa

    PubMed Central

    van Breugel, Paulo; Kindt, Roeland; Lillesø, Jens-Peter Barnekow; van Breugel, Michiel

    2015-01-01

    Countries in eastern Africa have set aside significant proportions of their land for protection. But are these areas representative of the diverse range of species and habitats found in the region? And do conservation efforts include areas where the state of biodiversity is likely to deteriorate without further interventions? Various studies have addressed these questions at global and continental scales. However, meaningful conservation decisions are required at finer geographical scales. To operate more effectively at the national level, finer scale baseline data on species and on higher levels of biological organization such as the eco-regions are required, among other factors. Here we adopted a recently developed high-resolution potential natural vegetation (PNV) map for eastern Africa as a baseline to more effectively identify conservation priorities. We examined how well different potential natural vegetations (PNVs) are represented in the protected area (PA) network of eastern Africa and used a multivariate environmental similarity index to evaluate biases in PA versus PNV coverage. We additionally overlaid data of anthropogenic factors that potentially influence the natural vegetation to assess the level of threat to different PNVs. Our results indicate substantial differences in the conservation status of PNVs. In addition, particular PNVs in which biodiversity protection and ecological functions are at risk due to human influences are revealed. The data and approach presented here provide a step forward in developing more transparent and better informed translation from global priorities to regional or national implementation in eastern Africa, and are valid for other geographic regions. PMID:25855968

  4. Computational study of the transition state for H[sub 2] addition to Vaska-type complexes (trans-Ir(L)[sub 2](CO)X). Substituent effects on the energy barrier and the origin of the small H[sub 2]/D[sub 2] kinetic isotope effect

    SciTech Connect

    Abu-Hasanayn, F.; Goldman, A.S.; Krogh-Jespersen, K. )

    1993-06-03

    Ab initio molecular orbital methods have been used to study transition state properties for the concerted addition reaction of H[sub 2] to Vaska-type complexes, trans-Ir(L)[sub 2](CO)X, 1 (L = PH[sub 3] and X = F, Cl, Br, I, CN, or H; L = NH[sub 3] and X = Cl). Stationary points on the reaction path retaining the trans-L[sub 2] arrangement were located at the Hartree-Fock level using relativistic effective core potentials and valence basis sets of double-[zeta] quality. The identities of the stationary points were confirmed by normal mode analysis. Activation energy barriers were calculated with electron correlation effects included via Moller-Plesset perturbation theory carried fully through fourth order, MP4(SDTQ). The more reactive complexes feature structurally earlier transition states and larger reaction exothermicities, in accord with the Hammond postulate. The experimentally observed increase in reactivity of Ir(PPh[sub 3])[sub 2](CO)X complexes toward H[sub 2] addition upon going from X = F to X = I is reproduced well by the calculations and is interpreted to be a consequence of diminished halide-to-Ir [pi]-donation by the heavier halogens. Computed activation barriers (L = PH[sub 3]) range from 6.1 kcal/mol (X = H) to 21.4 kcal/mol (X = F). Replacing PH[sub 3] by NH[sub 3] when X = Cl increases the barrier from 14.1 to 19.9 kcal/mol. Using conventional transition state theory, the kinetic isotope effects for H[sub 2]/D[sub 2] addition are computed to lie between 1.1 and 1.7 with larger values corresponding to earlier transition states. Judging from the computational data presented here, tunneling appears to be unimportant for H[sub 2] addition to these iridium complexes. 51 refs., 4 tabs.

  5. Food Additives and Hyperkinesis

    ERIC Educational Resources Information Center

    Wender, Ester H.

    1977-01-01

    The hypothesis that food additives are causally associated with hyperkinesis and learning disabilities in children is reviewed, and available data are summarized. Available from: American Medical Association 535 North Dearborn Street Chicago, Illinois 60610. (JG)

  6. Smog control fuel additives

    SciTech Connect

    Lundby, W.

    1993-06-29

    A method is described of controlling, reducing or eliminating, ozone and related smog resulting from photochemical reactions between ozone and automotive or industrial gases comprising the addition of iodine or compounds of iodine to hydrocarbon-base fuels prior to or during combustion in an amount of about 1 part iodine per 240 to 10,000,000 parts fuel, by weight, to be accomplished by: (a) the addition of these inhibitors during or after the refining or manufacturing process of liquid fuels; (b) the production of these inhibitors for addition into fuel tanks, such as automotive or industrial tanks; or (c) the addition of these inhibitors into combustion chambers of equipment utilizing solid fuels for the purpose of reducing ozone.

  7. Efforts to Consolidate Chalcogels with Adsorbed Iodine

    SciTech Connect

    Riley, Brian J.; Pierce, David A.; Chun, Jaehun

    2013-08-28

    This document discusses ongoing work with non-oxide aerogels, called chalcogels, that are under development at the Pacific Northwest National Laboratory as sorbents for gaseous iodine. Work was conducted in fiscal year 2012 to demonstrate the feasibility of converting Sn2S3 chalcogel without iodine into a glass. This current document summarizes the work conducted in fiscal year 2013 to assess the consolidation potential of non-oxide aerogels with adsorbed iodine. The Sn2S3 and Sb13.5Sn5S20 chalcogels were selected for study. The first step in the process for these experiments was to load them with iodine (I2). The I2 uptake was ~68 mass% for Sn2S3 and ~50 mass% for Sb13.5Sn5S20 chalcogels. X-ray diffraction (XRD) of both sets of sorbents showed that metal-iodide complexes were formed during adsorption, i.e., SnI4 for Sn2S3 and SbI3 for Sb13.5Sn5S20. Additionally, metal-sulfide-iodide complexes were formed, i.e., SnSI for Sn2S3 and SbSI for Sb13.5Sn5S20. No XRD evidence for unreacted iodine was found in any of these samples. Once the chalcogels had reached maximum adsorption, the consolidation potential was assessed. Here, the sorbents were heated for consolidation in vacuum-sealed quartz vessels. The Sb13.5Sn5S20 chalcogel was heated both (1) in a glassy carbon crucible within a fused quartz tube and (2) in a single-containment fused quartz tube. The Sn2S3 chalcogel was only heated in a single-containment fused quartz tube. In both cases with the single-containment fused quartz experiments, the material consolidated nicely. However, in both cases, there were small fractions of metal iodides not incorporated into the final product as well as fused quartz particles within the melt due to the sample attacking the quartz wall during the heat treatment. The Sb13.5Sn5S20 did not appear to attack the glassy carbon crucible so, for future experiments, it would be ideal to apply a coating, such as pyrolytic graphite, to the inner walls of the fused quartz vessel to prevent

  8. Computer Technology and Social Issues.

    ERIC Educational Resources Information Center

    Garson, G. David

    Computing involves social issues and political choices. Issues such as privacy, computer crime, gender inequity, disemployment, and electronic democracy versus "Big Brother" are addressed in the context of efforts to develop a national public policy for information technology. A broad range of research and case studies are examined in an…

  9. Children, Computers, and School Furniture.

    ERIC Educational Resources Information Center

    Maxwell, Lorraine E.

    1999-01-01

    Discusses the rise of posture-related discomfort and injury in children using computers in their classrooms and explores the research in the area. Recommends greater effort in encouraging school furniture manufacturers to create ergonomically appropriate computer workstations. Advice on what children can do to lessen musculoskeletal discomfort…

  10. Implementing Equal Access Computer Labs.

    ERIC Educational Resources Information Center

    Clinton, Janeen; And Others

    This paper discusses the philosophy followed in Palm Beach County to adapt computer literacy curriculum, hardware, and software to meet the needs of all children. The Department of Exceptional Student Education and the Department of Instructional Computing Services cooperated in planning strategies and coordinating efforts to implement equal…

  11. Site Protection Efforts at the AURA Observatory in Chile

    NASA Astrophysics Data System (ADS)

    Smith, R. Chris; Smith, Malcolm G.; Sanhueza, Pedro

    2015-08-01

    The AURA Observatory (AURA-O) was the first of the major international observatories to be established in northern Chile to exploit the optimal astronomical conditions available there. The site was originally established in 1962 to host the Cerro Tololo Inter-American Observatory (CTIO). It now hosts more than 20 operational telescopes, including some of the leading U.S. and international astronomical facilities in the southern hemisphere, such as the Blanco 4m telescope on Cerro Tololo and the Gemini-South and SOAR telescopes on Cerro Pachón. Construction of the next generation facility, the Large Synoptic Survey Telescope (LSST), has recently begun on Cerro Pachón, while additional smaller telescopes continue to be added to the complement on Cerro Tololo.While the site has become a major platform for international astronomical facilities over the last 50 years, development in the region has led to an ever-increasing threat of light pollution around the site. AURA-O has worked closely with local, regional, and national authorities and institutions (in particular with the Chilean Ministries of Environment and Foreign Relations) in an effort to protect the site so that future generations of telescopes, as well as future generations of Chileans, can benefit from the dark skies in the region. We will summarize our efforts over the past 15 years to highlight the importance of dark sky protection through education and public outreach as well as through more recent promotion of IDA certifications in the region and support for the World Heritage initiatives described by others in this conference.

  12. Adaptive effort investment in cognitive and physical tasks: a neurocomputational model.

    PubMed

    Verguts, Tom; Vassena, Eliana; Silvetti, Massimo

    2015-01-01

    Despite its importance in everyday life, the computational nature of effort investment remains poorly understood. We propose an effort model obtained from optimality considerations, and a neurocomputational approximation to the optimal model. Both are couched in the framework of reinforcement learning. It is shown that choosing when or when not to exert effort can be adaptively learned, depending on rewards, costs, and task difficulty. In the neurocomputational model, the limbic loop comprising anterior cingulate cortex (ACC) and ventral striatum in the basal ganglia allocates effort to cortical stimulus-action pathways whenever this is valuable. We demonstrate that the model approximates optimality. Next, we consider two hallmark effects from the cognitive control literature, namely proportion congruency and sequential congruency effects. It is shown that the model exerts both proactive and reactive cognitive control. Then, we simulate two physical effort tasks. In line with empirical work, impairing the model's dopaminergic pathway leads to apathetic behavior. Thus, we conceptually unify the exertion of cognitive and physical effort, studied across a variety of literatures (e.g., motivation and cognitive control) and animal species.

  13. Chair Talk: Resources to Maximize Administrative Efforts

    NASA Astrophysics Data System (ADS)

    MacDonald, H.; Chan, M. A.; Bierly, E. W.; Manduca, C. A.; Ormand, C. J.

    2009-12-01

    , dealing with difficult situations, working with alumni). Through the Association for Women Geoscientists, we have offered annual one-hour lunch discussions at AGU and GSA meetings on issues facing women chairs and deans. Focusing on a different topic each year, these discussions include sharing good solutions, problem solving on various case scenarios, and so forth. In addition, the Building Strong Geoscience Departments program has offered workshops on different aspects of building strong geoscience departments, distributed reports, and made a variety of materials that would be useful to geoscience chairs available on their website. These programs and resources should continue and build to provide more continuity within departments and to increase a broader experience base of faculty. One of the greatest resources for chairs is to have personal connections with other chairs (via these programs), who can be called upon for advice, ideas, or general support. The sense of collective community could act in a powerful way to inspire and encourage more innovations and creative solutions to promote stronger departments.

  14. Modulation of ventral striatal activity by cognitive effort.

    PubMed

    Dobryakova, Ekaterina; Jessup, Ryan K; Tricomi, Elizabeth

    2017-02-15

    Effort discounting theory suggests that the value of a reward should be lower if it was effortful to obtain, whereas contrast theory suggests that the contrast between the costly effort and the reward makes the reward seem more valuable. To test these alternative hypotheses, we used functional magnetic resonance imaging (fMRI) as participants engaged in feedback-based learning that required low or high cognitive effort to obtain positive feedback, while the objective amount of information provided by feedback remained constant. In the low effort condition, a single image was presented with four response options. In the high effort condition, two images were presented, each with two response options, and correct feedback was presented only when participants responded correctly to both of the images. Accuracy was significantly lower for the high effort condition, and all participants reported that the high effort condition was more difficult. A region of the ventral striatum selected for sensitivity to feedback value also showed increased activation to feedback presentation associated with the high effort condition relative to the low effort condition, when controlling for activation from corresponding control conditions where feedback was random. These results suggest that increased cognitive effort produces corresponding increases in positive feedback-related ventral striatum activity, in line with the predictions made by contrast theory. The accomplishment of obtaining a hard-earned intrinsic reward, such as positive feedback, may be particularly likely to promote reward-related brain activity.

  15. Statistical and computational challenges in physical mapping

    SciTech Connect

    Nelson, D.O.; Speed, T.P.

    1994-06-01

    One of the great success stories of modern molecular genetics has been the ability of biologists to isolate and characterize the genes responsible for serious inherited diseases like Huntington`s disease, cystic fibrosis, and myotonic dystrophy. Instrumental in these efforts has been the construction of so-called {open_quotes}physical maps{close_quotes} of large regions of human chromosomes. Constructing a physical map of a chromosome presents a number of interesting challenges to the computational statistician. In addition to the general ill-posedness of the problem, complications include the size of the data sets, computational complexity, and the pervasiveness of experimental error. The nature of the problem and the presence of many levels of experimental uncertainty make statistical approaches to map construction appealing. Simultaneously, however, the size and combinatorial complexity of the problem make such approaches computationally demanding. In this paper we discuss what physical maps are and describe three different kinds of physical maps, outlining issues which arise in constructing them. In addition, we describe our experience with powerful, interactive statistical computing environments. We found that the ability to create high-level specifications of proposed algorithms which could then be directly executed provided a flexible rapid prototyping facility for developing new statistical models and methods. The ability to check the implementation of an algorithm by comparing its results to that of an executable specification enabled us to rapidly debug both specification and implementation in an environment of changing needs.

  16. Cognitive trait anxiety, situational stress, and mental effort predict shifting efficiency: Implications for attentional control theory.

    PubMed

    Edwards, Elizabeth J; Edwards, Mark S; Lyvers, Michael

    2015-06-01

    Attentional control theory (ACT) predicts that trait anxiety and situational stress interact to impair performance on tasks that involve attentional shifting. The theory suggests that anxious individuals recruit additional effort to prevent shortfalls in performance effectiveness (accuracy), with deficits becoming evident in processing efficiency (the relationship between accuracy and time taken to perform the task). These assumptions, however, have not been systematically tested. The relationship between cognitive trait anxiety, situational stress, and mental effort in a shifting task (Wisconsin Card Sorting Task) was investigated in 90 participants. Cognitive trait anxiety was operationalized using questionnaire scores, situational stress was manipulated through ego threat instructions, and mental effort was measured using a visual analogue scale. Dependent variables were performance effectiveness (an inverse proportion of perseverative errors) and processing efficiency (an inverse proportion of perseverative errors divided by response time on perseverative error trials). The predictors were not associated with performance effectiveness; however, we observed a significant 3-way interaction on processing efficiency. At higher mental effort (+1 SD), higher cognitive trait anxiety was associated with poorer efficiency independently of situational stress, whereas at lower effort (-1 SD), this relationship was highly significant and most pronounced for those in the high-stress condition. These results are important because they provide the first systematic test of the relationship between trait anxiety, situational stress, and mental effort on shifting performance. The data are also consistent with the notion that effort moderates the relationship between anxiety and shifting efficiency, but not effectiveness.

  17. Group Sparse Additive Models

    PubMed Central

    Yin, Junming; Chen, Xi; Xing, Eric P.

    2016-01-01

    We consider the problem of sparse variable selection in nonparametric additive models, with the prior knowledge of the structure among the covariates to encourage those variables within a group to be selected jointly. Previous works either study the group sparsity in the parametric setting (e.g., group lasso), or address the problem in the nonparametric setting without exploiting the structural information (e.g., sparse additive models). In this paper, we present a new method, called group sparse additive models (GroupSpAM), which can handle group sparsity in additive models. We generalize the ℓ1/ℓ2 norm to Hilbert spaces as the sparsity-inducing penalty in GroupSpAM. Moreover, we derive a novel thresholding condition for identifying the functional sparsity at the group level, and propose an efficient block coordinate descent algorithm for constructing the estimate. We demonstrate by simulation that GroupSpAM substantially outperforms the competing methods in terms of support recovery and prediction accuracy in additive models, and also conduct a comparative experiment on a real breast cancer dataset.

  18. Additive Manufacturing Infrared Inspection

    NASA Technical Reports Server (NTRS)

    Gaddy, Darrell

    2014-01-01

    Additive manufacturing is a rapid prototyping technology that allows parts to be built in a series of thin layers from plastic, ceramics, and metallics. Metallic additive manufacturing is an emerging form of rapid prototyping that allows complex structures to be built using various metallic powders. Significant time and cost savings have also been observed using the metallic additive manufacturing compared with traditional techniques. Development of the metallic additive manufacturing technology has advanced significantly over the last decade, although many of the techniques to inspect parts made from these processes have not advanced significantly or have limitations. Several external geometry inspection techniques exist such as Coordinate Measurement Machines (CMM), Laser Scanners, Structured Light Scanning Systems, or even traditional calipers and gages. All of the aforementioned techniques are limited to external geometry and contours or must use a contact probe to inspect limited internal dimensions. This presentation will document the development of a process for real-time dimensional inspection technique and digital quality record of the additive manufacturing process using Infrared camera imaging and processing techniques.

  19. Phenylethynyl Containing Reactive Additives

    NASA Technical Reports Server (NTRS)

    Connell, John W. (Inventor); Smith, Joseph G., Jr. (Inventor); Hergenrother, Paul M. (Inventor)

    2002-01-01

    Phenylethynyl containing reactive additives were prepared from aromatic diamine, containing phenylethvnvl groups and various ratios of phthalic anhydride and 4-phenylethynviphthalic anhydride in glacial acetic acid to form the imide in one step or in N-methyl-2-pvrrolidinone to form the amide acid intermediate. The reactive additives were mixed in various amounts (10% to 90%) with oligomers containing either terminal or pendent phenylethynyl groups (or both) to reduce the melt viscosity and thereby enhance processability. Upon thermal cure, the additives react and become chemically incorporated into the matrix and effect an increase in crosslink density relative to that of the host resin. This resultant increase in crosslink density has advantageous consequences on the cured resin properties such as higher glass transition temperature and higher modulus as compared to that of the host resin.

  20. Fused Lasso Additive Model

    PubMed Central

    Petersen, Ashley; Witten, Daniela; Simon, Noah

    2016-01-01

    We consider the problem of predicting an outcome variable using p covariates that are measured on n independent observations, in a setting in which additive, flexible, and interpretable fits are desired. We propose the fused lasso additive model (FLAM), in which each additive function is estimated to be piecewise constant with a small number of adaptively-chosen knots. FLAM is the solution to a convex optimization problem, for which a simple algorithm with guaranteed convergence to a global optimum is provided. FLAM is shown to be consistent in high dimensions, and an unbiased estimator of its degrees of freedom is proposed. We evaluate the performance of FLAM in a simulation study and on two data sets. Supplemental materials are available online, and the R package flam is available on CRAN. PMID:28239246

  1. Phenylethynyl Containing Reactive Additives

    NASA Technical Reports Server (NTRS)

    Connell, John W. (Inventor); Smith, Joseph G., Jr. (Inventor); Hergenrother, Paul M. (Inventor)

    2002-01-01

    Phenylethynyl containing reactive additives were prepared from aromatic diamines containing phenylethynyl groups and various ratios of phthalic anhydride and 4-phenylethynylphthalic anhydride in glacial acetic acid to form the imide in one step or in N-methyl-2-pyrrolidi none to form the amide acid intermediate. The reactive additives were mixed in various amounts (10% to 90%) with oligomers containing either terminal or pendent phenylethynyl groups (or both) to reduce the melt viscosity and thereby enhance processability. Upon thermal cure, the additives react and become chemically incorporated into the matrix and effect an increase in crosslink density relative to that of the host resin. This resultant increase in crosslink density has advantageous consequences on the cured resin properties such as higher glass transition temperature and higher modulus as compared to that of the host resin.

  2. Additives in plastics.

    PubMed Central

    Deanin, R D

    1975-01-01

    The polymers used in plastics are generally harmless. However, they are rarely used in pure form. In almost all commercial plastics, they are "compounded" with monomeric ingredients to improve their processing and end-use performance. In order of total volume used, these monomeric additives may be classified as follows: reinforcing fibers, fillers, and coupling agents; plasticizers; colorants; stabilizers (halogen stabilizers, antioxidants, ultraviolet absorbers, and biological preservatives); processing aids (lubricants, others, and flow controls); flame retardants, peroxides; and antistats. Some information is already available, and much more is needed, on potential toxicity and safe handling of these additives during processing and manufacture of plastics products. PMID:1175566

  3. Additives in plastics.

    PubMed

    Deanin, R D

    1975-06-01

    The polymers used in plastics are generally harmless. However, they are rarely used in pure form. In almost all commercial plastics, they are "compounded" with monomeric ingredients to improve their processing and end-use performance. In order of total volume used, these monomeric additives may be classified as follows: reinforcing fibers, fillers, and coupling agents; plasticizers; colorants; stabilizers (halogen stabilizers, antioxidants, ultraviolet absorbers, and biological preservatives); processing aids (lubricants, others, and flow controls); flame retardants, peroxides; and antistats. Some information is already available, and much more is needed, on potential toxicity and safe handling of these additives during processing and manufacture of plastics products.

  4. Neutron Characterization for Additive Manufacturing

    NASA Technical Reports Server (NTRS)

    Watkins, Thomas; Bilheux, Hassina; An, Ke; Payzant, Andrew; DeHoff, Ryan; Duty, Chad; Peter, William; Blue, Craig; Brice, Craig A.

    2013-01-01

    Oak Ridge National Laboratory (ORNL) is leveraging decades of experience in neutron characterization of advanced materials together with resources such as the Spallation Neutron Source (SNS) and the High Flux Isotope Reactor (HFIR) shown in Fig. 1 to solve challenging problems in additive manufacturing (AM). Additive manufacturing, or three-dimensional (3-D) printing, is a rapidly maturing technology wherein components are built by selectively adding feedstock material at locations specified by a computer model. The majority of these technologies use thermally driven phase change mechanisms to convert the feedstock into functioning material. As the molten material cools and solidifies, the component is subjected to significant thermal gradients, generating significant internal stresses throughout the part (Fig. 2). As layers are added, inherent residual stresses cause warping and distortions that lead to geometrical differences between the final part and the original computer generated design. This effect also limits geometries that can be fabricated using AM, such as thin-walled, high-aspect- ratio, and overhanging structures. Distortion may be minimized by intelligent toolpath planning or strategic placement of support structures, but these approaches are not well understood and often "Edisonian" in nature. Residual stresses can also impact component performance during operation. For example, in a thermally cycled environment such as a high-pressure turbine engine, residual stresses can cause components to distort unpredictably. Different thermal treatments on as-fabricated AM components have been used to minimize residual stress, but components still retain a nonhomogeneous stress state and/or demonstrate a relaxation-derived geometric distortion. Industry, federal laboratory, and university collaboration is needed to address these challenges and enable the U.S. to compete in the global market. Work is currently being conducted on AM technologies at the ORNL

  5. [Trends in the utilization of food additives].

    PubMed

    Szűcs, Viktória; Bánáti, Diána

    2013-11-17

    The frequent media reports on food additives weakened consumers' trust in food producers and food control authorities as well. Furthermore, consumers' uncertainty is also raised by the fact that they obtain their information from inadequate, mistrustful sources and, therefore, consumers might avoid the consumption of certain foodstuffs. While food producers may react by replacing artificial components by natural ones, they try to emphasize the favourable characteristics of their products. The authors describe the main trends and efforts related to food additives. On the basis of the overview it can be concluded that - besides taking into consideration consumers' needs - product development and research directions are promising. Food producers' efforts may help to restore consumer confidence and trust and they may help them to have informed choice.

  6. Biobased lubricant additives

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Fully biobased lubricants are those formulated using all biobased ingredients, i.e. biobased base oils and biobased additives. Such formulations provide the maximum environmental, safety, and economic benefits expected from a biobased product. Currently, there are a number of biobased base oils that...

  7. More Than Additional Space...

    ERIC Educational Resources Information Center

    CEFP Journal, 1973

    1973-01-01

    A much needed addition to the Jamestown Elementary School turned out to be more than an expansion of walls for more space. A new educational program, a limited budget, and a short time line were tackled on a team approach basis and were successfully resolved. (Author)

  8. Evaluating cognitive effort in a randomized controlled trial.

    PubMed

    Turner, Travis H; Renfroe, Jenna B; Morella, Kristen; Marriott, Bernadette P

    2016-09-01

    Many randomized controlled trials (RCTs) of neuropsychiatric conditions involve cognitive outcome measures; however, validity of cognitive data relies on adequate effort during testing, and such screening is seldom performed. Given well-established rates of 10 to 30% poor effort in clinical settings, this is not a trivial concern. This preliminary study evaluated effort during cognitive testing in an RCT of omega-3 supplementation to reduce suicidality in a high-risk psychiatric population. An interim analysis of sustained attentions measures from the Connors Performance Test (CPT-2) at baseline for the first 60 participants was conducted. Previously validated cut points to detect insufficient effort on the CPT-2 were applied. At baseline, 12% (7) were identified as giving poor effort. Follow-up analyses indicated less psychiatric distress and suicidality among those who gave poor effort. Results suggest comparable likelihood of a poor effort on cognitive testing in clinical and RCT participation. Reduced psychiatric distress in the poor effort group raises concern regarding interpretation of other measures. The importance of screening cognitive data for effort in RCTs is highlighted. Future studies will examine effort at follow-up visits, and explore relationships to attrition, adherence, and response to treatment. Copyright © 2016 John Wiley & Sons, Ltd.

  9. The Stevens Personal Computer Plan.

    ERIC Educational Resources Information Center

    Friedman, Edward A.; Moeller, Joseph J., Jr.

    1984-01-01

    Describes evolution, implementation, and development of a personal computer plan at Stevens Institute of Technology (New Jersey). Although Stevens was the first college to establish a personal computer requirement, the core curriculum could not accommodate additional computing courses. Therefore, computing was integrated throughout the entire…

  10. Computers and Computer Cultures.

    ERIC Educational Resources Information Center

    Papert, Seymour

    1981-01-01

    Instruction using computers is viewed as different from most other approaches to education, by allowing more than right or wrong answers, by providing models for systematic procedures, by shifting the boundary between formal and concrete processes, and by influencing the development of thinking in many new ways. (MP)

  11. Additional extensions to the NASCAP computer code, volume 2

    NASA Technical Reports Server (NTRS)

    Stannard, P. R.; Katz, I.; Mandell, M. J.

    1982-01-01

    Particular attention is given to comparison of the actural response of the SCATHA (Spacecraft Charging AT High Altitudes) P78-2 satellite with theoretical (NASCAP) predictions. Extensive comparisons for a variety of environmental conditions confirm the validity of the NASCAP model. A summary of the capabilities and range of validity of NASCAP is presented, with extensive reference to previously published applications. It is shown that NASCAP is capable of providing quantitatively accurate results when the object and environment are adequately represented and fall within the range of conditions for which NASCAP was intended. Three dimensional electric field affects play an important role in determining the potential of dielectric surfaces and electrically isolated conducting surfaces, particularly in the presence of artificially imposed high voltages. A theory for such phenomena is presented and applied to the active control experiments carried out in SCATHA, as well as other space and laboratory experiments. Finally, some preliminary work toward modeling large spacecraft in polar Earth orbit is presented. An initial physical model is presented including charge emission. A simple code based upon the model is described along with code test results.

  12. Relationship effort, satisfaction, and stability: differences across union type.

    PubMed

    Shafer, Kevin; Jensen, Todd M; Larson, Jeffry H

    2014-04-01

    Relationship satisfaction and stability are two commonly studied outcomes in marriage and family research. Majority of studies address socio demographic variability and differences across union type in these outcomes. We extend this literature by addressing how the amount of effort one puts into their relationship is associated with stability and satisfaction. Specifically, we focus on how effort impacts these measures of quality in four union types: premarital cohabitation, first marriage, post-divorce cohabitation, and second marriage following divorce. Furthermore, we make union type comparisons in the strength of effort's association with satisfaction and stability. Using data from 8,006 respondents in the Relationship Evaluation Survey, our results show that effort was strongly and positively associated with satisfaction and stability in all four unions. Although effort is more strongly associated with satisfaction in first marriage than cohabiting relationships, no union type differences in the role of effort on stability were observed. Clinical and research implications of these findings are discussed.

  13. Vinyl capped addition polyimides

    NASA Technical Reports Server (NTRS)

    Vannucci, Raymond D. (Inventor); Malarik, Diane C. (Inventor); Delvigs, Peter (Inventor)

    1991-01-01

    Polyimide resins (PMR) are generally useful where high strength and temperature capabilities are required (at temperatures up to about 700 F). Polyimide resins are particularly useful in applications such as jet engine compressor components, for example, blades, vanes, air seals, air splitters, and engine casing parts. Aromatic vinyl capped addition polyimides are obtained by reacting a diamine, an ester of tetracarboxylic acid, and an aromatic vinyl compound. Low void materials with improved oxidative stability when exposed to 700 F air may be fabricated as fiber reinforced high molecular weight capped polyimide composites. The aromatic vinyl capped polyimides are provided with a more aromatic nature and are more thermally stable than highly aliphatic, norbornenyl-type end-capped polyimides employed in PMR resins. The substitution of aromatic vinyl end-caps for norbornenyl end-caps in addition polyimides results in polymers with improved oxidative stability.

  14. Electrophilic addition of astatine

    SciTech Connect

    Norseev, Yu.V.; Vasaros, L.; Nhan, D.D.; Huan, N.K.

    1988-03-01

    It has been shown for the first time that astatine is capable of undergoing addition reactions to unsaturated hydrocarbons. A new compound of astatine, viz., ethylene astatohydrin, has been obtained, and its retention numbers of squalane, Apiezon, and tricresyl phosphate have been found. The influence of various factors on the formation of ethylene astatohydrin has been studied. It has been concluded on the basis of the results obtained that the univalent cations of astatine in an acidic medium is protonated hypoastatous acid.

  15. CAD/CAM (Computer-Aided Design/Computer-Aided Manufacturing) Highlights.

    DTIC Science & Technology

    1984-10-01

    AD-Aift 532 CAD/CAN (COMPUTER-AIDED DESIGN /COMPUTER-ADD D7 MANUFACTURING) HIGHLIGHTSMU ARMY INDUSTRIAL BASE ENGINEERING ACTIVITY ROCK ISLAND IL D L...1985 B DISCLAIMER This document presents information for the US Army Materiel Command (AMC) Computer-Alded Design /Computer-Aided Manufacturing...contains summaries of Army Computer-Aided Design (CAD) and . Computer-Aided Manufacturing (CAM) efforts that are either completed or ongoing. The Army CAD

  16. Functional Generalized Additive Models.

    PubMed

    McLean, Mathew W; Hooker, Giles; Staicu, Ana-Maria; Scheipl, Fabian; Ruppert, David

    2014-01-01

    We introduce the functional generalized additive model (FGAM), a novel regression model for association studies between a scalar response and a functional predictor. We model the link-transformed mean response as the integral with respect to t of F{X(t), t} where F(·,·) is an unknown regression function and X(t) is a functional covariate. Rather than having an additive model in a finite number of principal components as in Müller and Yao (2008), our model incorporates the functional predictor directly and thus our model can be viewed as the natural functional extension of generalized additive models. We estimate F(·,·) using tensor-product B-splines with roughness penalties. A pointwise quantile transformation of the functional predictor is also considered to ensure each tensor-product B-spline has observed data on its support. The methods are evaluated using simulated data and their predictive performance is compared with other competing scalar-on-function regression alternatives. We illustrate the usefulness of our approach through an application to brain tractography, where X(t) is a signal from diffusion tensor imaging at position, t, along a tract in the brain. In one example, the response is disease-status (case or control) and in a second example, it is the score on a cognitive test. R code for performing the simulations and fitting the FGAM can be found in supplemental materials available online.

  17. Mothers' teaching strategies and children's effortful control: a longitudinal study.

    PubMed

    Eisenberg, Nancy; Vidmar, Masa; Spinrad, Tracy L; Eggum, Natalie D; Edwards, Alison; Gaertner, Bridget; Kupfer, Anne

    2010-09-01

    Findings on the relation of maternal verbal teaching strategies to children's effortful control (EC; i.e., self-regulation) are limited in quantity and somewhat inconsistent. In this study, children's EC was assessed at 18, 30, and 42 months (ns = 255, 229, and 209, respectively) with adults' reports and a behavioral measure. Mothers' verbal teaching strategies were assessed while the mother and child worked on a task together. Children's general vocabulary also was measured. In a structural panel model taking into account prior levels of constructs and correlations within time, as well as the relations of EC and teaching strategies to children's vocabulary, socioeconomic status, age, and sex of the child, 18-month EC positively predicted mothers' 30-month cognitive assistance and questioning strategies and negatively predicted 30-month maternal directive strategies. In addition, high 30-month EC predicted greater 42-month maternal cognitive assistance and fewer directive strategies. Thus, mothers' teaching strategies were predicted by individual differences in self-regulatory skills, supporting potential evocative child effects on mothers' teaching strategies.

  18. Sustainability Characterization for Additive Manufacturing

    PubMed Central

    Mani, Mahesh; Lyons, Kevin W; Gupta, SK

    2014-01-01

    Additive manufacturing (AM) has the potential to create geometrically complex parts that require a high degree of customization, using less material and producing less waste. Recent studies have shown that AM can be an economically viable option for use by the industry, yet there are some inherent challenges associated with AM for wider acceptance. The lack of standards in AM impedes its use for parts production since industries primarily depend on established standards in processes and material selection to ensure the consistency and quality. Inability to compare AM performance against traditional manufacturing methods can be a barrier for implementing AM processes. AM process sustainability has become a driver due to growing environmental concerns for manufacturing. This has reinforced the importance to understand and characterize AM processes for sustainability. Process characterization for sustainability will help close the gaps for comparing AM performance to traditional manufacturing methods. Based on a literature review, this paper first examines the potential environmental impacts of AM. A methodology for sustainability characterization of AM is then proposed to serve as a resource for the community to benchmark AM processes for sustainability. Next, research perspectives are discussed along with relevant standardization efforts. PMID:26601038

  19. Sustainability Characterization for Additive Manufacturing.

    PubMed

    Mani, Mahesh; Lyons, Kevin W; Gupta, S K

    2014-01-01

    Additive manufacturing (AM) has the potential to create geometrically complex parts that require a high degree of customization, using less material and producing less waste. Recent studies have shown that AM can be an economically viable option for use by the industry, yet there are some inherent challenges associated with AM for wider acceptance. The lack of standards in AM impedes its use for parts production since industries primarily depend on established standards in processes and material selection to ensure the consistency and quality. Inability to compare AM performance against traditional manufacturing methods can be a barrier for implementing AM processes. AM process sustainability has become a driver due to growing environmental concerns for manufacturing. This has reinforced the importance to understand and characterize AM processes for sustainability. Process characterization for sustainability will help close the gaps for comparing AM performance to traditional manufacturing methods. Based on a literature review, this paper first examines the potential environmental impacts of AM. A methodology for sustainability characterization of AM is then proposed to serve as a resource for the community to benchmark AM processes for sustainability. Next, research perspectives are discussed along with relevant standardization efforts.

  20. Treatment of Pica Using a Pica Exchange Procedure with Increasing Response Effort

    ERIC Educational Resources Information Center

    Carter, Stacy L.

    2009-01-01

    The effects of a pica exchange procedure were evaluated on the pica of a female with severe mental retardation. A BAB design revealed that the pica exchange procedure was effective at reducing the occurrence of pica. In addition, the pica exchange procedure was effective throughout six increasingly more difficult response effort conditions.…

  1. Unconscious Reward Cues Increase Invested Effort, but Do Not Change Speed-Accuracy Tradeoffs

    ERIC Educational Resources Information Center

    Bijleveld, Erik; Custers, Ruud; Aarts, Henk

    2010-01-01

    While both conscious and unconscious reward cues enhance effort to work on a task, previous research also suggests that conscious rewards may additionally affect speed-accuracy tradeoffs. Based on this idea, two experiments explored whether reward cues that are presented above (supraliminal) or below (subliminal) the threshold of conscious…

  2. Stochastic evolutionary dynamics in minimum-effort coordination games

    NASA Astrophysics Data System (ADS)

    Li, Kun; Cong, Rui; Wang, Long

    2016-08-01

    The minimum-effort coordination game draws recently more attention for the fact that human behavior in this social dilemma is often inconsistent with the predictions of classical game theory. Here, we combine evolutionary game theory and coalescence theory to investigate this game in finite populations. Both analytic results and individual-based simulations show that effort costs play a key role in the evolution of contribution levels, which is in good agreement with those observed experimentally. Besides well-mixed populations, set structured populations have also been taken into consideration. Therein we find that large number of sets and moderate migration rate greatly promote effort levels, especially for high effort costs.

  3. The relationship of IQ to effort test performance.

    PubMed

    Dean, Andy C; Victor, Tara L; Boone, Kyle B; Arnold, Ginger

    2008-07-01

    The relationship between IQ and nine effort indicators was examined in a sample of 189 neuropsychology clinic outpatients who were not in litigation or attempting to obtain disability. Participants with the lowest IQ (50-59) failed approximately 60% of the effort tests, while patients with an IQ of 60 to 69 failed 44% of effort indicators, and individuals with borderline IQ (70 to 79) exhibited a 17% failure rate. All patients with IQ < 70 failed at least one effort test. Cutoffs for the Warrington Recognition Memory Test (Words) and Finger Tapping maintained the highest specificities in low IQ samples.

  4. Characterization of reward and effort mechanisms in apathy.

    PubMed

    Bonnelle, Valerie; Veromann, Kai-Riin; Burnett Heyes, Stephanie; Lo Sterzo, Elena; Manohar, Sanjay; Husain, Masud

    2015-01-01

    Apathy is a common but poorly understood condition with a wide societal impact observed in several brain disorders as well as, to some extent, in the normal population. Hence the need for better characterization of the underlying mechanisms. The processes by which individuals decide to attribute physical effort to obtain rewards might be particularly relevant to relate to apathy traits. Here, we designed two paradigms to assess individual differences in physical effort production and effort-based decision-making and their relation to apathy in healthy people. Apathy scores were measured using a modified version of the Lille Apathy Rating Scale, suitable for use in a non-clinical population. In the first study, apathy scores were correlated with the degree to which stake (reward on offer) and difficulty level impacts on physical effort production. Individuals with relatively high apathy traits showed an increased modulation of effort while more motivated individuals generally exerted greater force across different levels of stake. To clarify the underlying mechanisms for this behavior, we designed a second task that allows independent titration of stake and effort levels for which subjects are willing to engage in an effortful response to obtain a reward. Our results suggest that apathy traits in the normal population are related to the way reward subjectively affects the estimation of effort costs, and more particularly manifest as decreased willingness to exert effort when rewards are small, or below threshold. The tasks we introduce here may provide useful tools to further investigate apathy in clinical populations.

  5. Feedforward consequences of isometric contractions: effort and ventilation.

    PubMed

    Luu, Billy L; Smith, Janette L; Martin, Peter G; McBain, Rachel A; Taylor, Janet L; Butler, Jane E

    2016-08-01

    The onset of voluntary muscle contractions causes rapid increases in ventilation and is accompanied by a sensation of effort. Both the ventilatory response and perception of effort are proportional to contraction intensity, but these behaviors have been generalized from contractions of a single muscle group. Our aim was to determine how these relationships are affected by simultaneous contractions of multiple muscle groups. We examined the ventilatory response and perceived effort of contraction during separate and simultaneous isometric contractions of the contralateral elbow flexors and of an ipsilateral elbow flexor and knee extensor. Subjects made 10-sec contractions at 25, 50, and 100% of maximum during normocapnia and hypercapnia. For simultaneous contractions, both muscle groups were activated at the same intensities. Ventilation was measured continuously and subjects rated the effort required to produce each contraction. As expected, ventilation and perceived effort increased proportionally with contraction intensity during individual contractions. However, during simultaneous contractions, neither ventilation nor effort reflected the combined muscle output. Rather, the ventilatory response was similar to when contractions were performed separately, and effort ratings showed a small but significant increase for simultaneous contractions. Hypercapnia at rest doubled baseline ventilation, but did not affect the difference in perceived effort between separate and simultaneous contractions. The ventilatory response and the sense of effort at the onset of muscle activity are not related to the total output of the motor pathways, or the working muscles, but arise from cortical regions upstream from the motor cortex.

  6. Theory of atomic additivity in molecular hyperpolizabilities

    NASA Technical Reports Server (NTRS)

    Baird, James K.

    1987-01-01

    Hyperpolarizability is a function of frequency. This is called dispersion. Because of the Kramers-Kronig relations, researchers expect that a material that is dispersing light is also absorbing it. Where there is both dispersion and absorption, the molecular polarizabilities are complex functions of the frequency. This led researchers to consider atomic additivity in both the real and imaginary parts of the ordinary and hyperpolarizabilities. This effort is desirable not only from a theoretical point of view, but also because of the existence of a large body of complex refractive index data, which may be used to test the additivity principle with the complex valued ordinary dipole polarizability.

  7. Computational geomechanics & applications at Sandia National Laboratories.

    SciTech Connect

    Arguello, Jose Guadalupe, Jr.

    2010-04-01

    Sandia National Laboratories (SNL) is a multi-program national laboratory in the business of national security, whose primary mission is nuclear weapons (NW). It is a prime contractor to the USDOE, operating under the NNSA and is one of the three NW national laboratories. It has a long history of involvement in the area of geomechanics, starting with the some of the earliest weapons tests at Nevada. Projects in which geomechanics support (in general) and computational geomechanics support (in particular) are at the forefront at Sandia, range from those associated with civilian programs to those in the defense programs. SNL has had significant involvement and participation in the Waste Isolation Pilot Plant (low-level defense nuclear waste), the Yucca Mountain Project (formerly proposed for commercial spent fuel and high-level nuclear waste), and the Strategic Petroleum Reserve (the nation's emergency petroleum store). In addition, numerous industrial partners seek-out our computational/geomechanics expertise, and there are efforts in compressed air and natural gas storage, as well as in CO{sub 2} Sequestration. Likewise, there have also been collaborative past efforts in the areas of compactable reservoir response, the response of salt structures associated with reservoirs, and basin modeling for the Oil & Gas industry. There are also efforts on the defense front, ranging from assessment of vulnerability of infrastructure to defeat of hardened targets, which require an understanding and application of computational geomechanics. Several examples from some of these areas will be described and discussed to give the audience a flavor of the type of work currently being performed at Sandia in the general area of geomechanics.

  8. Siloxane containing addition polyimides

    NASA Technical Reports Server (NTRS)

    Maudgal, S.; St. Clair, T. L.

    1984-01-01

    Addition polyimide oligomers have been synthesized from bis(gamma-aminopropyl) tetramethyldisiloxane and 3, 3', 4, 4'-benzophenonetetracarboxylic dianhydride using a variety of latent crosslinking groups as endcappers. The prepolymers were isolated and characterized for solubility (in amide, chlorinated and ether solvents), melt flow and cure properties. The most promising systems, maleimide and acetylene terminated prepolymers, were selected for detailed study. Graphite cloth reinforced composites were prepared and properties compared with those of graphite/Kerimid 601, a commercially available bismaleimide. Mixtures of the maleimide terminated system with Kerimid 601, in varying proportions, were also studied.

  9. Effect of Social Influence on Effort-Allocation for Monetary Rewards

    PubMed Central

    Gilman, Jodi M.; Treadway, Michael T.; Curran, Max T.; Calderon, Vanessa; Evins, A. Eden

    2015-01-01

    Though decades of research have shown that people are highly influenced by peers, few studies have directly assessed how the value of social conformity is weighed against other types of costs and benefits. Using an effort-based decision-making paradigm with a novel social influence manipulation, we measured how social influence affected individuals’ decisions to allocate effort for monetary rewards during trials with either high or low probability of receiving a reward. We found that information about the effort-allocation of peers modulated participant choices, specifically during conditions of low probability of obtaining a reward. This suggests that peer influence affects effort-based choices to obtain rewards especially under conditions of risk. This study provides evidence that people value social conformity in addition to other costs and benefits when allocating effort, and suggests that neuroeconomic studies that assess trade-offs between effort and reward should consider social environment as a factor that can influence decision-making. PMID:25961725

  10. A Pilot Study to Evaluate Development Effort for High Performance Computing

    DTIC Science & Technology

    2006-01-01

    speaker I am not a native speaker [Please complete the following] TOEFL Score Year My English reading comprehension skills are...Undergraduate Major General Background Please estimate your English language background: I am a native...Low Medium High My English listening and speaking skills are: Low Medium High How many

  11. A Review of Computational Spinal Injury Biomechanics Research and Recommendations for Future Efforts

    DTIC Science & Technology

    2011-09-01

    critical for the diagnosis and management of osteoporosis . The current clinical standard to predict vertebral strength is to perform a bone mineral...should be three-dimensional and include all anatomic components of the spine necessary to capture the physics of interest, namely, injury mechanisms...199 (6), 875–879. 4. Ramasamy, A.; Hill, A. M.; Hepper, A. E.; Bull, A. M. J.; Clasper, J. C. Blast Mines: Physics , Injury Mechanisms and Vehicle

  12. Validation Efforts of the Pacific Northwest River Restoration Database

    NASA Astrophysics Data System (ADS)

    McFall, J. M.; Katz, S. L.; Morehead, M. D.

    2005-12-01

    The improvement of science in river restoration relies heavily on the evaluation of previously established projects in order to assess the ecosystem response and project outcome (Bernhard et al, 2005). To facilitate this, there needs to be competent project tracking and documentation of outcomes. In the Pacific Northwest, the National Marine Fisheries Service's Northwest Fisheries Science Center has compiled a database containing over 26,000 restoration actions at 36,000 locations in Oregon, Washington, Idaho, and Montana (Katz, et al. in review). Recent efforts have been undertaken to validate this database through selection of random samples for telephone interviews and field site visits. 47 project managers were interviewed via telephone regarding their restoration activities within four project category intents. In addition, six Columbia River sub-basins were selected for site validation sampling of 170 projects. The basins included for site validations are the Lemhi and Pahsimeroi Rivers in Idaho, the Methow and Entiat Rivers in Washington, and the Upper and Lower John Day Rivers in Oregon. Survey results are presented with statistical estimators to validate the database. Regional trends in river restoration were found to exist and differences were found between reporting agencies and on the smaller, local scale. The implementation of restoration activities is examined to see if projects are being instigated as intended and case studies are examined to reveal lessons learned from practitioners. In general, the effectiveness of various river restoration activities in the Pacific Northwest would be better charted through standardization in project tracking and documentation. References Bernhardt, E. S., Palmer, M. A., Allan, J. D., Alexander, G., Barnas, K., Brooks, S., Carr, J., Clayton, S., Dahm, C., Follstad-Shah, J., Galat, D., Gloss, S., Goodwin, P., Hart, D., Hassett, B., Jenkinson, J., Katz, S., Kondolf, G. M., Lake, P. S., Lave, R., Meyer, J. L., O

  13. Platelet additive solution - electrolytes.

    PubMed

    Azuma, Hiroshi; Hirayama, Junichi; Akino, Mitsuaki; Ikeda, Hisami

    2011-06-01

    Recent attention to solutions that replace most or all plasma in platelet concentrates, while maintaining satisfactory platelet function, is motivated by the potential of plasma reduction or depletion to mitigate various transfusion-related adverse events. This report considers the electrolytic composition of previously described platelet additive solutions, in order to draw general conclusions about what is required for platelet function and longevity. The optimal concentrations of Na(+) and Cl(-) are 69-115 mM. The presence of both K(+) and Mg(2+) in platelet suspension at nearly physiological concentrations (3-5mM and 1.5-3mM, respectively) is indispensable for good preservation capacity because both electrolytes are required to prevent platelet activation. In contrast to K(+) and Mg(2+), Ca(2+) may not be important because no free Ca(2+) is available in M-sol, which showed excellent platelet preservation capacity at less than 5% plasma concentration. The importance of bicarbonate (approximately 40 mM) can be recognized when the platelets are suspended in additive solution under less than 5% residual plasma concentration.

  14. A synopsis of Langley Research Center's lidar effort for the 1986 FIRE IFO

    NASA Technical Reports Server (NTRS)

    Alvarez, Jose M.; Mccormick, M. P.; Moore, J. D.; Hunt, W. H.; Rouse, B. R.; Poole, L. R.; Poole, B. D.

    1990-01-01

    The lidar data obtained by the Langley Aircraft Lidar in October 1986 in Wisconsin is being reduced in a transparent, simple fashion and will be published in its reduced form in a NASA Reference Publication (RP). This reduced data will also be submitted to the FIRE data archives. Some of this reduced data will be presented at the FIRE FSET Workshop to acquaint the science team with the data format to be used in the archive and the upcoming catalog contained in the RP. A new method was utilized in Wisconsin for obtain the depolarization ratio of aerosols. This method involves using a half-wave plate to calibrate the lidar under field conditions. The theory behind this technique will be presented at this workshop as well as some of the lidar calibration results. The lidar calibration will be utilized in interpreting some of the dual polarization lidar data obtained during the IFO in Wisconsin. Some of these data are also discussed. A continuous wave laser lab-type lidar simulator was constructed during the previous year. One of the primary reasons for the construction of the simulator was to attempt dual-polarization lidar-like calibrations under laboratory, rather than field conditions. The data collected by this system was used to experimentally check and thus, inspire confidence in the algorithms being used to interpret the lidar data obtained in the field. A computer program which simulates noisy lidar data was used as a part of this effort in order to obtain some feel for the noise in the inversion parameters as a function of noise in the actual measurements. The lidar simulation will be described in addition to presenting some of the lab-generated calibration data.

  15. Preparing Future Secondary Computer Science Educators

    ERIC Educational Resources Information Center

    Ajwa, Iyad

    2007-01-01

    Although nearly every college offers a major in computer science, many computer science teachers at the secondary level have received little formal training. This paper presents details of a project that could make a significant contribution to national efforts to improve computer science education by combining teacher education and professional…

  16. 34 CFR 300.203 - Maintenance of effort.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true Maintenance of effort. 300.203 Section 300.203 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Local Educational Agency Eligibility § 300.203 Maintenance of effort. (a) General. Except...

  17. Estimating Software Effort Hours for Major Defense Acquisition Programs

    ERIC Educational Resources Information Center

    Wallshein, Corinne C.

    2010-01-01

    Software Cost Estimation (SCE) uses labor hours or effort required to conceptualize, develop, integrate, test, field, or maintain program components. Department of Defense (DoD) SCE can use initial software data parameters to project effort hours for large, software-intensive programs for contractors reporting the top levels of process maturity,…

  18. Institutional Effects of Strategic Efforts at Community Enrichment.

    ERIC Educational Resources Information Center

    Mawhinney, Hanne B.

    1994-01-01

    Prepares the way for an institutional analysis of strategic interventions for collaboration, drawing on recent research by Crowson, Boyd, and other organizational theorists. Using a framework of institutional propositions, analyzes strategic efforts to promote collaborative efforts to enhance students' life chances in a Canadian high school, as…

  19. Control of robotic assistance using poststroke residual voluntary effort.

    PubMed

    Makowski, Nathaniel S; Knutson, Jayme S; Chae, John; Crago, Patrick E

    2015-03-01

    Poststroke hemiparesis limits the ability to reach, in part due to involuntary muscle co-activation (synergies). Robotic approaches are being developed for both therapeutic benefit and continuous assistance during activities of daily living. Robotic assistance may enable participants to exert less effort, thereby reducing expression of the abnormal co-activation patterns, which could allow participants to reach further. This study evaluated how well participants could perform a reaching task with robotic assistance that was either provided independent of effort in the vertical direction or in the sagittal plane in proportion to voluntary effort estimated from electromyograms (EMG) on the affected side. Participants who could not reach targets without assistance were enabled to reach further with assistance. Constant anti-gravity force assistance that was independent of voluntary effort did not reduce the quality of reach and enabled participants to exert less effort while maintaining different target locations. Force assistance that was proportional to voluntary effort on the affected side enabled participants to exert less effort and could be controlled to successfully reach targets, but participants had increased difficulty maintaining a stable position. These results suggest that residual effort on the affected side can produce an effective command signal for poststroke assistive devices.

  20. NASA cryogenic fluid management space experiment efforts, 1960-1990

    NASA Technical Reports Server (NTRS)

    Glover, Daniel

    1991-01-01

    A history of technological development for subcritical cryogenic fluid management (CFM) through space experiments is given for the period 1960 to 1990. Space experiments with liquid hydrogen were conducted in the early 1960's. Efforts since then have consisted of studies and designs of potential space experiments. A chronology of CFM space experiments and design efforts is included.

  1. Inefficient Effort Allocation and Negative Symptoms in Individuals with Schizophrenia

    PubMed Central

    McCarthy, Julie M.; Treadway, Michael T.; Bennett, Melanie E.; Blanchard, Jack J.

    2016-01-01

    Negative symptoms like avolition and anhedonia are thought to involve difficulties with reward processing and motivation. The current study aimed to replicate and extend prior findings that individuals with schizophrenia display reduced willingness to expend effort for rewards and that such reduced effort is associated with negative symptoms, poor functioning, and cognitive impairment. The present study compared the effortful decision making of individuals with schizophrenia (n = 48) and healthy controls (n = 27) on the Effort Expenditure for Rewards Task (EEfRT). Individuals with schizophrenia chose a smaller proportion of hard tasks than healthy controls across all probability and reward levels with the exception of trials with a 12% probability and low or medium reward magnitude wherein both groups chose similarly few hard tasks. Contrary to expectations, in individuals with schizophrenia, greater negative symptoms were associated with making more effortful choices. Effortful decision making was unrelated to positive symptoms, depression, cognition, and functioning in individuals with schizophrenia. Our results are consistent with prior findings that revealed a pattern of inefficient decision making in individuals with schizophrenia relative to healthy controls. However the results did not support the hypothesized association of negative symptoms and reduced effort in schizophrenia and highlight prior inconsistencies in this literature. Future research is needed to understand what factors may be related to diminished effortful decision making in schizophrenia and the clinical significance of such performance deficits. PMID:26763628

  2. Student Organizations and Institutional Diversity Efforts: A Typology

    ERIC Educational Resources Information Center

    Kuk, Linda; Banning, James

    2010-01-01

    American higher education has become focused on increasing access and success for traditionally underrepresented populations. Despite the myriad of institutional efforts, attention has not been given to the role of student organizations in supporting these efforts. This article looks at the role campus student organizations can play within campus…

  3. Current Reform Efforts in Mathematics Education. ERIC/CSMEE Digest.

    ERIC Educational Resources Information Center

    Edwards, Thomas G.

    The current reform effort in mathematics education has its roots in the decade of the 1980's and the national reports that focused attention on an impending crisis in education, particularly in mathematics and science. Within this context, dozens of individual reform efforts have been initiated in recent years. Many have focused on the development…

  4. Heuristics Made Easy: An Effort-Reduction Framework

    ERIC Educational Resources Information Center

    Shah, Anuj K.; Oppenheimer, Daniel M.

    2008-01-01

    In this article, the authors propose a new framework for understanding and studying heuristics. The authors posit that heuristics primarily serve the purpose of reducing the effort associated with a task. As such, the authors propose that heuristics can be classified according to a small set of effort-reduction principles. The authors use this…

  5. Motivation and effort in individuals with social anhedonia.

    PubMed

    McCarthy, Julie M; Treadway, Michael T; Blanchard, Jack J

    2015-06-01

    It has been proposed that anhedonia may, in part, reflect difficulties in reward processing and effortful decision making. The current study aimed to replicate previous findings of effortful decision making deficits associated with elevated anhedonia and expand upon these findings by investigating whether these decision making deficits are specific to elevated social anhedonia or are also associated with elevated positive schizotypy characteristics. The current study compared controls (n=40) to individuals elevated on social anhedonia (n=30), and individuals elevated on perceptual aberration/magical ideation (n=30) on the Effort Expenditure for Rewards Task (EEfRT). Across groups, participants chose a higher proportion of hard tasks with increasing probability of reward and reward magnitude, demonstrating sensitivity to probability and reward values. Contrary to our expectations, when the probability of reward was most uncertain (50% probability), at low and medium reward values, the social anhedonia group demonstrated more effortful decision making than either individuals high in positive schizotypy or controls. The positive schizotypy group only differed from controls (making less effortful choices than controls) when reward probability was lowest (12%) and the magnitude of reward was the smallest. Our results suggest that social anhedonia is related to intact motivation and effort for monetary rewards, but that individuals with this characteristic display a unique and perhaps inefficient pattern of effort allocation when the probability of reward is most uncertain. Future research is needed to better understand effortful decision making and the processing of reward across a range of individual difference characteristics.

  6. A Measure of Local Effort, 1981-82.

    ERIC Educational Resources Information Center

    Stewart, Gerald

    Three lengthy tables and four charts present information on the 1981-82 planned tax effort of each of Pennsylvania's 501 school districts and 67 counties. The tax effort, or "equalized mills," equals each district's budgeted taxes divided by its projected 1981 market value. The report gives a brief illustration of how the tax effort…

  7. Are Effortful and Reactive Control Unique Constructs in Young Children?

    ERIC Educational Resources Information Center

    Eisenberg, Nancy; Edwards, Alison; Spinrad, Tracy L.; Sallquist, Julie; Eggum, Natalie D.; Reiser, Mark

    2013-01-01

    The primary goal of this study was to examine whether effortful control (EC; effortful regulation), reactive undercontrol (IMP; e.g., impulsivity, speed of approach), and reactive overcontrol (NOV; inhibition to novelty) were 3 distinct constructs at 30 months (Time 1; n = 216), 42 months (Time 2; n = 192), and 54 months (Time 3; n = 168) of age.…

  8. Group Diffusion of Cognitive Effort as a Determinant of Attribution.

    ERIC Educational Resources Information Center

    Quintanar, Leo R.; Pryor, John B.

    The tendency for individuals to reduce their own efforts when others are available to respond has been called "social loafing." Social loafing has been found also to characterize collective endeavors on tasks considered cognitively efffortful. To test the hypothesis that reduced cognitive effort related to the presence of a coacting group would…

  9. Effects of Effortful Swallow on Cardiac Autonomic Regulation.

    PubMed

    Gomes, Lívia M S; Silva, Roberta G; Melo, Monique; Silva, Nayra N; Vanderlei, Franciele M; Garner, David M; de Abreu, Luiz Carlos; Valenti, Vitor E

    2016-04-01

    Swallowing-induced changes in heart rate have been recently reported. However, it is not apparent the responses of heart rate variability (HRV) elicited by effortful swallow maneuver. We investigated the acute effects of effortful swallowing maneuver on HRV. This study was performed on 34 healthy women between 18 and 35 years old. We assessed heart rate variability in the time (SDNN, RMSSD, and pNN50) and frequency (HF, LF, and LF/HF ratio) domains and, visual analysis through the Poincaré plot. The subjects remained at rest for 5 min during spontaneous swallowing and then performed effortful swallowing for 5 min. HRV was analyzed during spontaneous and effortful swallowing. We found no significant differences for SDNN, pNN50, RMSSD, HF in absolute units (ms(2)). There is a trend for increase of LF in absolute (p = 0.05) and normalized (p = 0.08) units during effortful swallowing. HF in normalized units reduced (p = 0.02) during effortful swallowing and LF/HF ratio (p = 0.03) increased during effortful swallowing. In conclusion effortful swallow maneuver in healthy women increased sympathetic cardiac modulation, indicating a cardiac overload.

  10. Assessing the Army Power and Energy Efforts for the Warfighter

    DTIC Science & Technology

    2011-03-01

    Stirling devices), and a considerable effort on chemical storage batteries. Not until recently has the effort broadened to include alternative sources of...Neal A. Pollard, and Robert V. Tuohy, Hicks & Associates, Inc., Tyson’s Corner, VA., 2004. 34 National Research Council, Science and Technology for

  11. 24 CFR 245.205 - Efforts to obtain assistance.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Efforts to obtain assistance. (a) Mortgagors subject to the requirements of this subpart shall not interfere with the efforts of tenants to obtain rent subsidies or other public assistance. (b) A mortgagor subject to the requirements of this subpart who is a party to a rent supplement contract under section...

  12. 48 CFR 1352.231-71 - Duplication of effort.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Duplication of effort. 1352.231-71 Section 1352.231-71 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CLAUSES... Duplication of effort. As prescribed in 48 CFR 1331.205-70, insert the following clause: Duplication of...

  13. Does Effort Still Count?: More on What Makes the Grade

    ERIC Educational Resources Information Center

    Zinn, Tracy E.; Magnotti, John F.; Marchuk, Kimberly; Schultz, Bridget S.; Luther, Andrew; Varfolomeeva, Veronika

    2011-01-01

    Previous research has examined differences between students and faculty regarding the weight of effort in assigning grades. Here, students and faculty responded to questions regarding the relative weight of performance and effort on final grades and what letter grades faculty should assign across different types of courses. The authors asked these…

  14. 29 CFR 102.173 - Relation to other collection efforts.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Relation to other collection efforts. 102.173 Section 102.173 Labor Regulations Relating to Labor NATIONAL LABOR RELATIONS BOARD RULES AND REGULATIONS, SERIES 8... efforts. (a) Tax refund offset is intended to be an administrative collection remedy to be...

  15. 34 CFR 300.204 - Exception to maintenance of effort.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Exception to maintenance of effort. 300.204 Section 300.204 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL... effort. Notwithstanding the restriction in § 300.203(a), an LEA may reduce the level of expenditures...

  16. 40 CFR 35.405 - Maintenance of effort.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Maintenance of effort. 35.405 Section 35.405 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE... Maintenance of effort. To receive funds under section 205(g), a State agency must expend annually...

  17. 12 CFR 918.7 - Maintenance of effort.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Maintenance of effort. 918.7 Section 918.7 Banks and Banking FEDERAL HOUSING FINANCE BOARD GOVERNANCE AND MANAGEMENT OF THE FEDERAL HOME LOAN BANKS BANK DIRECTOR COMPENSATION AND EXPENSES § 918.7 Maintenance of effort. Notwithstanding the limits...

  18. 40 CFR 35.266 - Maintenance of effort.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Maintenance of effort. 35.266 Section 35.266 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE....266 Maintenance of effort. To receive section 319 funds in any fiscal year, a State must agree...

  19. 24 CFR 115.305 - Special enforcement effort (SEE) funds.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Special enforcement effort (SEE) funds. 115.305 Section 115.305 Housing and Urban Development Regulations Relating to Housing and Urban... Housing Assistance Program § 115.305 Special enforcement effort (SEE) funds. (a) SEE funds are funds...

  20. 40 CFR 35.636 - Maintenance of effort.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Maintenance of effort. 35.636 Section 35.636 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE... (sections 319(h) and 518(f)) § 35.636 Maintenance of effort. To receive funds under section 319 in...

  1. Predictors of neuropsychological effort test performance in schizophrenia.

    PubMed

    Morra, Lindsay F; Gold, James M; Sullivan, Sara K; Strauss, Gregory P

    2015-03-01

    There is some evidence that insufficient effort may be common in schizophrenia, posing significant threats to the validity of neuropsychological test results. Low effort may account for a significant proportion of variance in neuropsychological test scores and the generalized cognitive deficit that characterizes the disorder. The current study evaluated clinical predictors of insufficient effort in schizophrenia using an embedded effort measure, the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) Effort Index (EI). Participants were 330 patients meeting DSM-IV-TR criteria for schizophrenia, schizoaffective disorder, or another psychotic disorder who received a battery of neuropsychological tests, including: Wechsler Test of Adult Reading (WTAR), Wechsler Abbreviated Scale of Intelligence (WASI), and RBANS. Clinical assessments designed to measure functional outcome and symptoms were also obtained. Results indicated that 9.4% of patients failed the EI. Patients who failed had lower full-scale, verbal, and performance IQ, as well as poorer performance on RBANS domains not included in the EI (immediate memory, language, and visuospatial/construction). Patients who failed the EI also displayed poorer community-based vocational outcome, greater likelihood of having "deficit schizophrenia" (i.e., primary and enduring negative symptoms), and increased severity of positive symptoms. Regression analyses revealed that insufficient effort was most significantly predicted by a combination of low IQ, negative symptoms, and positive symptoms. Findings suggest that although insufficient effort may be relatively uncommon in schizophrenia, it is associated with important clinical outcomes. The RBANS EI may be a useful tool in evaluating insufficient effort in schizophrenia.

  2. Mental Effort in Binary Categorization Aided by Binary Cues

    ERIC Educational Resources Information Center

    Botzer, Assaf; Meyer, Joachim; Parmet, Yisrael

    2013-01-01

    Binary cueing systems assist in many tasks, often alerting people about potential hazards (such as alarms and alerts). We investigate whether cues, besides possibly improving decision accuracy, also affect the effort users invest in tasks and whether the required effort in tasks affects the responses to cues. We developed a novel experimental tool…

  3. 34 CFR 300.203 - Maintenance of effort.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Maintenance of effort. 300.203 Section 300.203 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES Local Educational Agency Eligibility § 300.203 Maintenance of effort....

  4. Student Perception of Academic Grading: Personality, Academic Orientation, and Effort

    ERIC Educational Resources Information Center

    Tippin, Gregory K.; Lafreniere, Kathryn D.; Page, Stewart

    2012-01-01

    Factors influencing student perceptions of academic grading were examined, with an emphasis on furthering understanding of the relevance of effort to students' conceptualization of grading. Students demonstrated a conceptualization of grading where effort should be weighted comparably to actual performance in importance to the composition of a…

  5. 14 CFR 1204.1510 - Efforts to accommodate intergovernmental concerns.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Efforts to accommodate intergovernmental concerns. 1204.1510 Section 1204.1510 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION... Programs and Activities § 1204.1510 Efforts to accommodate intergovernmental concerns. (a) If a...

  6. 29 CFR 20.106 - Relation to other collection efforts.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Relation to other collection efforts. 20.106 Section 20.106 Labor Office of the Secretary of Labor FEDERAL CLAIMS COLLECTION Federal Income Tax Refund Offset § 20.106 Relation to other collection efforts. (a) Tax refund offset is intended to be an...

  7. Desktop Computing Integration Project

    NASA Technical Reports Server (NTRS)

    Tureman, Robert L., Jr.

    1992-01-01

    The Desktop Computing Integration Project for the Human Resources Management Division (HRMD) of LaRC was designed to help division personnel use personal computing resources to perform job tasks. The three goals of the project were to involve HRMD personnel in desktop computing, link mainframe data to desktop capabilities, and to estimate training needs for the division. The project resulted in increased usage of personal computers by Awards specialists, an increased awareness of LaRC resources to help perform tasks, and personal computer output that was used in presentation of information to center personnel. In addition, the necessary skills for HRMD personal computer users were identified. The Awards Office was chosen for the project because of the consistency of their data requests and the desire of employees in that area to use the personal computer.

  8. Computer Music

    NASA Astrophysics Data System (ADS)

    Cook, Perry R.

    This chapter covers algorithms, technologies, computer languages, and systems for computer music. Computer music involves the application of computers and other digital/electronic technologies to music composition, performance, theory, history, and the study of perception. The field combines digital signal processing, computational algorithms, computer languages, hardware and software systems, acoustics, psychoacoustics (low-level perception of sounds from the raw acoustic signal), and music cognition (higher-level perception of musical style, form, emotion, etc.).

  9. Effortful Control, Surgency, and reading skills in middle childhood

    PubMed Central

    Deater-Deckard, Kirby; Mullineaux, Paula Y.; Petrill, Stephen A.; Thompson, Lee A.

    2010-01-01

    We examined the associations between components of temperament and children’s word and pseudo-word reading skills, in a school-age sample using a within-family internal-replication design. We estimated the statistical prediction of word and pseudo-word reading in separate regression equations that included the main effects of, and two-way interaction between, Surgency and Effortful Control. Children with better Effortful Control scores showed better reading skills. Surgency was unrelated to reading skills, but moderated the effect of Effortful Control. The positive association between reading skills and Effortful Control was present only for children who were low in Surgency. Thus, reading achievement in school-age children is optimized by strong Effortful Control, but these processes may be disrupted for those children who are high in Surgency. PMID:20526377

  10. Neural encoding of competitive effort in the anterior cingulate cortex.

    PubMed

    Hillman, Kristin L; Bilkey, David K

    2012-09-01

    In social environments, animals often compete to obtain limited resources. Strategically electing to work against another animal represents a cost-benefit decision. Is the resource worth an investment of competitive effort? The anterior cingulate cortex (ACC) has been implicated in cost-benefit decision-making, but its role in competitive effort has not been examined. We recorded ACC neurons in freely moving rats as they performed a competitive foraging choice task. When at least one of the two choice options demanded competitive effort, the majority of ACC neurons exhibited heightened and differential firing between the goal trajectories. Inter- and intrasession manipulations revealed that differential firing was not attributable to effort or reward in isolation; instead ACC encoding patterns appeared to indicate net utility assessments of available choice options. Our findings suggest that the ACC is important for encoding competitive effort, a cost-benefit domain that has received little neural-level investigation despite its predominance in nature.

  11. 47 CFR 68.318 - Additional limitations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... TERMINAL EQUIPMENT TO THE TELEPHONE NETWORK Conditions for Terminal Equipment Approval § 68.318 Additional... activation. Note to paragraph (b)(1): Emergency alarm dialers and dialers under external computer control are... proceeding to dial another number. (6) Network addressing signals shall be transmitted no earlier than:...

  12. Additive composition, for gasoline

    SciTech Connect

    Vataru, M.

    1989-01-10

    An admixture is described that comprises Diesel fuel and an additive composition added thereto which is between about 0.05 to about 2.0 percent by weight of the fuel, the composition comprising: (a) between about 0.05 and 25% relative weight parts of an organic peroxide, and (b) between about 0.1 and 25% relative weight parts of detergent selected from the component group that consists of: (i) fatty amines; (ii) ethoxylated and propoxylated derivatives of fatty amines; (iii) fatty diamines; (iv) fatty imidazlines; (v) polymeric amines and derivatives thereof; (vi) combination of one or more of the (i) through (v) components with carboxylic acid or acids having from three to forth carbon atoms, (c) from about 99.0 to about 50% by weight of a hydrocarbon solvent.

  13. New addition curing polyimides

    NASA Technical Reports Server (NTRS)

    Frimer, Aryeh A.; Cavano, Paul

    1991-01-01

    In an attempt to improve the thermal-oxidative stability (TOS) of PMR-type polymers, the use of 1,4-phenylenebis (phenylmaleic anhydride) PPMA, was evaluated. Two series of nadic end-capped addition curing polyimides were prepared by imidizing PPMA with either 4,4'-methylene dianiline or p-phenylenediamine. The first resulted in improved solubility and increased resin flow while the latter yielded a compression molded neat resin sample with a T(sub g) of 408 C, close to 70 C higher than PME-15. The performance of these materials in long term weight loss studies was below that of PMR-15, independent of post-cure conditions. These results can be rationalized in terms of the thermal lability of the pendant phenyl groups and the incomplete imidization of the sterically congested PPMA. The preparation of model compounds as well as future research directions are discussed.

  14. Perspectives on Additive Manufacturing

    NASA Astrophysics Data System (ADS)

    Bourell, David L.

    2016-07-01

    Additive manufacturing (AM) has skyrocketed in visibility commercially and in the public sector. This article describes the development of this field from early layered manufacturing approaches of photosculpture, topography, and material deposition. Certain precursors to modern AM processes are also briefly described. The growth of the field over the last 30 years is presented. Included is the standard delineation of AM technologies into seven broad categories. The economics of AM part generation is considered, and the impacts of the economics on application sectors are described. On the basis of current trends, the future outlook will include a convergence of AM fabricators, mass-produced AM fabricators, enabling of topology optimization designs, and specialization in the AM legal arena. Long-term developments with huge impact are organ printing and volume-based printing.

  15. Sewage sludge additive

    NASA Technical Reports Server (NTRS)

    Kalvinskas, J. J.; Mueller, W. A.; Ingham, J. D. (Inventor)

    1980-01-01

    The additive is for a raw sewage treatment process of the type where settling tanks are used for the purpose of permitting the suspended matter in the raw sewage to be settled as well as to permit adsorption of the dissolved contaminants in the water of the sewage. The sludge, which settles down to the bottom of the settling tank is extracted, pyrolyzed and activated to form activated carbon and ash which is mixed with the sewage prior to its introduction into the settling tank. The sludge does not provide all of the activated carbon and ash required for adequate treatment of the raw sewage. It is necessary to add carbon to the process and instead of expensive commercial carbon, coal is used to provide the carbon supplement.

  16. Computer software documentation

    NASA Technical Reports Server (NTRS)

    Comella, P. A.

    1973-01-01

    A tutorial in the documentation of computer software is presented. It presents a methodology for achieving an adequate level of documentation as a natural outgrowth of the total programming effort commencing with the initial problem statement and definition and terminating with the final verification of code. It discusses the content of adequate documentation, the necessity for such documentation and the problems impeding achievement of adequate documentation.

  17. Computer Music

    NASA Astrophysics Data System (ADS)

    Cook, Perry

    This chapter covers algorithms, technologies, computer languages, and systems for computer music. Computer music involves the application of computers and other digital/electronic technologies to music composition, performance, theory, history, and perception. The field combines digital signal processing, computational algorithms, computer languages, hardware and software systems, acoustics, psychoacoustics (low-level perception of sounds from the raw acoustic signal), and music cognition (higher-level perception of musical style, form, emotion, etc.). Although most people would think that analog synthesizers and electronic music substantially predate the use of computers in music, many experiments and complete computer music systems were being constructed and used as early as the 1950s.

  18. Effort-reward imbalance and depression in Japanese medical residents.

    PubMed

    Sakata, Yumi; Wada, Koji; Tsutsumi, Akizumi; Ishikawa, Hiroyasu; Aratake, Yutaka; Watanabe, Mayumi; Katoh, Noritada; Aizawa, Yoshiharu; Tanaka, Katsutoshi

    2008-01-01

    The effort-reward imbalance is an important psychosocial factor which is related to poor health among employees. However, there are few studies that have evaluated effort-reward imbalance among medical residents. The present study was done to determine the association between psychosocial factors at work as defined by the effort-reward imbalance model and depression among Japanese medical residents. We distributed a questionnaire to 227 medical residents at 16 teaching hospitals in Japan at the end of August 2005. We asked participants to answer questions which included demographic information, depressive symptoms, effort-reward imbalance, over-commitment and social support. Depression was evaluated using the Japanese version of the Center for Epidemiologic Studies-Depression (CES-D) scale. The effort-reward imbalance and over-commitment were assessed by the Effort-Reward Imbalance (ERI) questionnaire which Siegrist developed. Social support was determined on a visual analog scale. Logistic regression analysis was performed to determine the associations between effort-reward imbalance and depressive symptoms. Depressive symptoms were found in 35 (29.2%) 1st-year residents and 21 (27.6%) 2nd-year residents. The effort-reward ratio >1 (OR, 8.83; 95% CI, 2.87-27.12) and low social support score (OR, 2.77, 95% CI, 1.36-5.64) were associated with depressive symptoms among medical residents. Effort-reward imbalance was independently related to depression among Japanese medical residents. The present study suggests that balancing between effort and reward at work is important for medical residents' mental health.

  19. Activities of information retrieval in Daicel Corporation : The roles and efforts of information retrieval team

    NASA Astrophysics Data System (ADS)

    Yamazaki, Towako

    In order to stabilize and improve quality of information retrieval service, the information retrieval team of Daicel Corporation has given some efforts on standard operating procedures, interview sheet for information retrieval, structured format for search report, and search expressions for some technological fields of Daicel. These activities and efforts will also lead to skill sharing and skill tradition between searchers. In addition, skill improvements are needed not only for a searcher individually, but also for the information retrieval team totally when playing searcher's new roles.

  20. A comparative analysis of soft computing techniques for gene prediction.

    PubMed

    Goel, Neelam; Singh, Shailendra; Aseri, Trilok Chand

    2013-07-01

    The rapid growth of genomic sequence data for both human and nonhuman species has made analyzing these sequences, especially predicting genes in them, very important and is currently the focus of many research efforts. Beside its scientific interest in the molecular biology and genomics community, gene prediction is of considerable importance in human health and medicine. A variety of gene prediction techniques have been developed for eukaryotes over the past few years. This article reviews and analyzes the application of certain soft computing techniques in gene prediction. First, the problem of gene prediction and its challenges are described. These are followed by different soft computing techniques along with their application to gene prediction. In addition, a comparative analysis of different soft computing techniques for gene prediction is given. Finally some limitations of the current research activities and future research directions are provided.

  1. Goal striving strategies and effort mobilization: When implementation intentions reduce effort-related cardiac activity during task performance.

    PubMed

    Freydefont, Laure; Gollwitzer, Peter M; Oettingen, Gabriele

    2016-09-01

    Two experiments investigate the influence of goal and implementation intentions on effort mobilization during task performance. Although numerous studies have demonstrated the beneficial effects of setting goals and making plans on performance, the effects of goals and plans on effort-related cardiac activity and especially the cardiac preejection period (PEP) during goal striving have not yet been addressed. According to the Motivational Intensity Theory, participants should increase effort mobilization proportionally to task difficulty as long as success is possible and justified. Forming goals and making plans should allow for reduced effort mobilization when participants perform an easy task. However, when the task is difficult, goals and plans should differ in their effect on effort mobilization. Participants who set goals should disengage, whereas participants who made if-then plans should stay in the field showing high effort mobilization during task performance. As expected, using an easy task in Experiment 1, we observed a lower cardiac PEP in both the implementation intention and the goal intention condition than in the control condition. In Experiment 2, we varied task difficulty and demonstrated that while participants with a mere goal intention disengaged from difficult tasks, participants with an implementation intention increased effort mobilization proportionally with task difficulty. These findings demonstrate the influence of goal striving strategies (i.e., mere goals vs. if-then plans) on effort mobilization during task performance.

  2. Additive lattice kirigami.

    PubMed

    Castle, Toen; Sussman, Daniel M; Tanis, Michael; Kamien, Randall D

    2016-09-01

    Kirigami uses bending, folding, cutting, and pasting to create complex three-dimensional (3D) structures from a flat sheet. In the case of lattice kirigami, this cutting and rejoining introduces defects into an underlying 2D lattice in the form of points of nonzero Gaussian curvature. A set of simple rules was previously used to generate a wide variety of stepped structures; we now pare back these rules to their minimum. This allows us to describe a set of techniques that unify a wide variety of cut-and-paste actions under the rubric of lattice kirigami, including adding new material and rejoining material across arbitrary cuts in the sheet. We also explore the use of more complex lattices and the different structures that consequently arise. Regardless of the choice of lattice, creating complex structures may require multiple overlapping kirigami cuts, where subsequent cuts are not performed on a locally flat lattice. Our additive kirigami method describes such cuts, providing a simple methodology and a set of techniques to build a huge variety of complex 3D shapes.

  3. Ceramics with Different Additives

    NASA Astrophysics Data System (ADS)

    Wang, Juanjuan; Feng, Lajun; Lei, Ali; Zhao, Kang; Yan, Aijun

    2014-09-01

    Li2CO3, MgCO3, BaCO3, and Bi2O3 dopants were introduced into CaCu3Ti4O12 (CCTO) ceramics in order to improve the dielectric properties. The CCTO ceramics were prepared by conventional solid-state reaction method. The phase structure, microstructure, and dielectric behavior were carefully investigated. The pure structure without any impurity phases can be confirmed by the x-ray diffraction patterns. Scanning Electron Microscopy (SEM) analysis illuminated that the grains of Ca0.90Li0.20Cu3Ti4O12 ceramics were greater than that of pure CCTO. It was important for the properties of the CCTO ceramics to study the additives in complex impedance spectroscopy. It was found that the Ca0.90Li0.20Cu3Ti4O12 ceramics had the higher permittivity (>45000), the lower dielectric loss (<0.025) than those of CCTO at 1 kHz at room temperature and good temperature stability from -30 to 75 °C.

  4. Additive lattice kirigami

    PubMed Central

    Castle, Toen; Sussman, Daniel M.; Tanis, Michael; Kamien, Randall D.

    2016-01-01

    Kirigami uses bending, folding, cutting, and pasting to create complex three-dimensional (3D) structures from a flat sheet. In the case of lattice kirigami, this cutting and rejoining introduces defects into an underlying 2D lattice in the form of points of nonzero Gaussian curvature. A set of simple rules was previously used to generate a wide variety of stepped structures; we now pare back these rules to their minimum. This allows us to describe a set of techniques that unify a wide variety of cut-and-paste actions under the rubric of lattice kirigami, including adding new material and rejoining material across arbitrary cuts in the sheet. We also explore the use of more complex lattices and the different structures that consequently arise. Regardless of the choice of lattice, creating complex structures may require multiple overlapping kirigami cuts, where subsequent cuts are not performed on a locally flat lattice. Our additive kirigami method describes such cuts, providing a simple methodology and a set of techniques to build a huge variety of complex 3D shapes. PMID:27679822

  5. Electrophysiological correlates of listening effort: neurodynamical modeling and measurement.

    PubMed

    Strauss, Daniel J; Corona-Strauss, Farah I; Trenado, Carlos; Bernarding, Corinna; Reith, Wolfgang; Latzel, Matthias; Froehlich, Matthias

    2010-06-01

    An increased listing effort represents a major problem in humans with hearing impairment. Neurodiagnostic methods for an objective listening effort estimation might support hearing instrument fitting procedures. However the cognitive neurodynamics of listening effort is far from being understood and its neural correlates have not been identified yet. In this paper we analyze the cognitive neurodynamics of listening effort by using methods of forward neurophysical modeling and time-scale electroencephalographic neurodiagnostics. In particular, we present a forward neurophysical model for auditory late responses (ALRs) as large-scale listening effort correlates. Here endogenously driven top-down projections related to listening effort are mapped to corticothalamic feedback pathways which were analyzed for the selective attention neurodynamics before. We show that this model represents well the time-scale phase stability analysis of experimental electroencephalographic data from auditory discrimination paradigms. It is concluded that the proposed neurophysical and neuropsychological framework is appropriate for the analysis of listening effort and might help to develop objective electroencephalographic methods for its estimation in future.

  6. Assessing country-level efforts to link research to action.

    PubMed Central

    Lavis, John N.; Lomas, Jonathan; Hamid, Maimunah; Sewankambo, Nelson K.

    2006-01-01

    We developed a framework for assessing country-level efforts to link research to action. The framework has four elements. The first element assesses the general climate (how those who fund research, universities, researchers and users of research support or place value on efforts to link research to action). The second element addresses the production of research (how priority setting ensures that users' needs are identified and how scoping reviews, systematic reviews and single studies are undertaken to address these needs). The third element addresses the mix of four clusters of activities used to link research to action. These include push efforts (how strategies are used to support action based on the messages arising from research), efforts to facilitate "user pull" (how "one-stop shopping" is provided for optimally packaged high-quality reviews either alone or as part of a national electronic library for health, how these reviews are profiled during "teachable moments" such as intense media coverage, and how rapid-response units meet users' needs for the best research), "user pull" efforts undertaken by those who use research (how users assess their capacity to use research and how structures and processes are changed to support the use of research) and exchange efforts (how meaningful partnerships between researchers and users help them to jointly ask and answer relevant questions). The fourth element addresses approaches to evaluation (how support is provided for rigorous evaluations of efforts to link research to action). PMID:16917649

  7. Oxygen uptake in maximal effort constant rate and interval running.

    PubMed

    Pratt, Daniel; O'Brien, Brendan J; Clark, Bradley

    2013-01-01

    This study investigated differences in average VO2 of maximal effort interval running to maximal effort constant rate running at lactate threshold matched for time. The average VO2 and distance covered of 10 recreational male runners (VO2max: 4158 ± 390 mL · min(-1)) were compared between a maximal effort constant-rate run at lactate threshold (CRLT), a maximal effort interval run (INT) consisting of 2 min at VO2max speed with 2 minutes at 50% of VO2 repeated 5 times, and a run at the average speed sustained during the interval run (CR submax). Data are presented as mean and 95% confidence intervals. The average VO2 for INT, 3451 (3269-3633) mL · min(-1), 83% VO2max, was not significantly different to CRLT, 3464 (3285-3643) mL · min(-1), 84% VO2max, but both were significantly higher than CR sub-max, 3464 (3285-3643) mL · min(-1), 76% VO2max. The distance covered was significantly greater in CLRT, 4431 (4202-3731) metres, compared to INT and CR sub-max, 4070 (3831-4309) metres. The novel finding was that a 20-minute maximal effort constant rate run uses similar amounts of oxygen as a 20-minute maximal effort interval run despite the greater distance covered in the maximal effort constant-rate run.

  8. The moderating effects of school climate on bullying prevention efforts.

    PubMed

    Low, Sabina; Van Ryzin, Mark

    2014-09-01

    Bullying prevention efforts have yielded mixed effects over the last 20 years. Program effectiveness is driven by a number of factors (e.g., program elements and implementation), but there remains a dearth of understanding regarding the role of school climate on the impact of bullying prevention programs. This gap is surprising, given research suggesting that bullying problems and climate are strongly related. The current study examines the moderating role of school climate on the impacts of a stand-alone bullying prevention curriculum. In addition, the current study examined 2 different dimensions of school climate across both student and staff perceptions. Data for this study were derived from a Steps to Respect (STR) randomized efficacy trial that was conducted in 33 elementary schools over a 1-year period. Schools were randomly assigned to intervention or wait-listed control condition. Outcome measures (pre-to-post) were obtained from (a) all school staff, (b) a randomly selected subset of 3rd-5th grade teachers in each school, and (c) all students in classrooms of selected teachers. Multilevel analyses revealed that psychosocial climate was strongly related to reductions in bullying-related attitudes and behaviors. Intervention status yielded only 1 significant main effect, although, STR schools with positive psychosocial climate at baseline had less victimization at posttest. Policies/administrative commitment to bullying were related to reduced perpetration among all schools. Findings suggest positive psychosocial climate (from both staff and student perspective) plays a foundational role in bullying prevention, and can optimize effects of stand-alone programs.

  9. Additive manufacturing of materials: Opportunities and challenges

    SciTech Connect

    Babu, Sudarsanam Suresh; Love, Lonnie J.; Dehoff, Ryan R.; Peter, William H.; Watkins, Thomas R.; Pannala, Sreekanth

    2015-11-01

    Additive manufacturing (also known as 3D printing) is considered a disruptive technology for producing components with topologically optimized complex geometries as well as functionalities that are not achievable by traditional methods. The realization of the full potential of 3D printing is stifled by a lack of computational design tools, generic material feedstocks, techniques for monitoring thermomechanical processes under in situ conditions, and especially methods for minimizing anisotropic static and dynamic properties brought about by microstructural heterogeneity. In this paper, we discuss the role of interdisciplinary research involving robotics and automation, process control, multiscale characterization of microstructure and properties, and high-performance computational tools to address each of these challenges. In addition, emerging pathways to scale up additive manufacturing of structural materials to large sizes (>1 m) and higher productivities (5–20 kg/h) while maintaining mechanical performance and geometrical flexibility are also discussed.

  10. Additive manufacturing of materials: Opportunities and challenges

    DOE PAGES

    Babu, Sudarsanam Suresh; Love, Lonnie J.; Dehoff, Ryan R.; ...

    2015-11-01

    Additive manufacturing (also known as 3D printing) is considered a disruptive technology for producing components with topologically optimized complex geometries as well as functionalities that are not achievable by traditional methods. The realization of the full potential of 3D printing is stifled by a lack of computational design tools, generic material feedstocks, techniques for monitoring thermomechanical processes under in situ conditions, and especially methods for minimizing anisotropic static and dynamic properties brought about by microstructural heterogeneity. In this paper, we discuss the role of interdisciplinary research involving robotics and automation, process control, multiscale characterization of microstructure and properties, and high-performancemore » computational tools to address each of these challenges. In addition, emerging pathways to scale up additive manufacturing of structural materials to large sizes (>1 m) and higher productivities (5–20 kg/h) while maintaining mechanical performance and geometrical flexibility are also discussed.« less

  11. System support software for the Space Ultrareliable Modular Computer (SUMC)

    NASA Technical Reports Server (NTRS)

    Hill, T. E.; Hintze, G. C.; Hodges, B. C.; Austin, F. A.; Buckles, B. P.; Curran, R. T.; Lackey, J. D.; Payne, R. E.

    1974-01-01

    The highly transportable programming system designed and implemented to support the development of software for the Space Ultrareliable Modular Computer (SUMC) is described. The SUMC system support software consists of program modules called processors. The initial set of processors consists of the supervisor, the general purpose assembler for SUMC instruction and microcode input, linkage editors, an instruction level simulator, a microcode grid print processor, and user oriented utility programs. A FORTRAN 4 compiler is undergoing development. The design facilitates the addition of new processors with a minimum effort and provides the user quasi host independence on the ground based operational software development computer. Additional capability is provided to accommodate variations in the SUMC architecture without consequent major modifications in the initial processors.

  12. Dopamine does double duty in motivating cognitive effort

    PubMed Central

    Westbrook, Andrew; Braver, Todd S.

    2015-01-01

    Cognitive control is subjectively costly, suggesting that engagement is modulated in relationship to incentive state. Dopamine appears to play key roles. In particular, dopamine may mediate cognitive effort by two broad classes of functions: 1) modulating the functional parameters of working memory circuits subserving effortful cognition, and 2) mediating value-learning and decision-making about effortful cognitive action. Here we tie together these two lines of research, proposing how dopamine serves “double duty”, translating incentive information into cognitive motivation. PMID:26889810

  13. Ground System Harmonization Efforts at NASA's Goddard Space Flight Center

    NASA Technical Reports Server (NTRS)

    Smith, Dan

    2011-01-01

    This slide presentation reviews the efforts made at Goddard Space Flight Center in harmonizing the ground systems to assist in collaboration in space ventures. The key elements of this effort are: (1) Moving to a Common Framework (2) Use of Consultative Committee for Space Data Systems (CCSDS) Standards (3) Collaboration Across NASA Centers (4) Collaboration Across Industry and other Space Organizations. These efforts are working to bring into harmony the GSFC systems with CCSDS standards to allow for common software, use of Commercial Off the Shelf Software and low risk development and operations and also to work toward harmonization with other NASA centers

  14. Cooling Computers.

    ERIC Educational Resources Information Center

    Birken, Marvin N.

    1967-01-01

    Numerous decisions must be made in the design of computer air conditioning, each determined by a combination of economics, physical, and esthetic characteristics, and computer requirements. Several computer air conditioning systems are analyzed--(1) underfloor supply and overhead return, (2) underfloor plenum and overhead supply with computer unit…

  15. Pygmalion's Computer.

    ERIC Educational Resources Information Center

    Peelle, Howard A.

    Computers have undoubtedly entered the educational arena, mainly in the areas of computer-assisted instruction (CAI) and artificial intelligence, but whether educators should embrace computers and exactly how they should use them are matters of great debate. The use of computers in support of educational administration is widely accepted.…

  16. Current efforts and future prospects in the development of live mycobacteria as vaccines.

    PubMed

    Ng, Tony W; Saavedra-Ávila, Noemí A; Kennedy, Steven C; Carreño, Leandro J; Porcelli, Steven A

    2015-01-01

    The development of more effective vaccines against Mycobacterium tuberculosis (Mtb) remains a major goal in the effort to reduce the enormous global burden of disease caused by this pathogen. Whole-cell vaccines based on live mycobacteria with attenuated virulence represent an appealing approach, providing broad antigen exposure and intrinsic adjuvant properties to prime durable immune responses. However, designing vaccine strains with an optimal balance between attenuation and immunogenicity has proven to be extremely challenging. Recent basic and clinical research efforts have broadened our understanding of Mtb pathogenesis and created numerous new vaccine candidates that have been designed to overcome different aspects of immune evasion by Mtb. In this review, we provide an overview of the current efforts to create improved vaccines against tuberculosis based on modifications of live attenuated mycobacteria. In addition, we discuss the use of such vaccine strains as vectors for stimulating protective immunity against other infectious diseases and cancers.

  17. Heritage Language Fluency, Ethnic Identity, and School Effort of Immigrant Chinese and Mexican Adolescents

    PubMed Central

    Kim, Su Yeong; Chao, Ruth K.

    2008-01-01

    The assumption that heritage language fluency is an essential component of ethnic identity, and that both factors are important predictors of school effort, was tested across two ethnic groups spanning multiple generations of immigrants. The sample consisted of 207 immigrant Chinese (first- and second-generation) and 354 Mexican (first-, second-, and third-generation) adolescents. The findings demonstrate that heritage language fluency is an important component of ethnic identity for second-generation Mexican adolescents, but not for second-generation Chinese adolescents. Thus, for this latter group, it may not be appropriate to use identity measures which assess heritage language fluency as a part of the general dimension of ethnic identity. The findings also show that higher reading and writing skills in Spanish are significant predictors of school effort for all three generations of Mexican adolescents; in addition, higher ethnic identity exploration is related to the school effort of second generation Mexican adolescents. PMID:19209978

  18. Heritage language fluency, ethnic identity, and school effort of immigrant Chinese and Mexico adolescents.

    PubMed

    Kim, Su Yeong; Chao, Ruth K

    2009-01-01

    The assumption that heritage language fluency is an essential component of ethnic identity, and that both factors are important predictors of school effort, was tested across two ethnic groups spanning multiple generations of immigrants. The sample consisted of 207 immigrant Chinese (first- and second-generation) and 354 Mexican (first-, second-, and third-generation) adolescents. The findings demonstrate that heritage language fluency is an important component of ethnic identity for second-generation Mexican adolescents, but not for second-generation Chinese adolescents. Thus, for this latter group, it may not be appropriate to use identity measures that assess heritage language fluency as a part of the general dimension of ethnic identity. The findings also show that higher reading and writing skills in Spanish are significant predictors of school effort for all three generations of Mexican adolescents; in addition, higher ethnic identity exploration is related to the school effort of second-generation Mexican adolescents.

  19. Human-computer interaction in multitask situations

    NASA Technical Reports Server (NTRS)

    Rouse, W. B.

    1977-01-01

    Human-computer interaction in multitask decisionmaking situations is considered, and it is proposed that humans and computers have overlapping responsibilities. Queueing theory is employed to model this dynamic approach to the allocation of responsibility between human and computer. Results of simulation experiments are used to illustrate the effects of several system variables including number of tasks, mean time between arrivals of action-evoking events, human-computer speed mismatch, probability of computer error, probability of human error, and the level of feedback between human and computer. Current experimental efforts are discussed and the practical issues involved in designing human-computer systems for multitask situations are considered.

  20. The updated algorithm of the Energy Consumption Program (ECP): A computer model simulating heating and cooling energy loads in buildings

    NASA Technical Reports Server (NTRS)

    Lansing, F. L.; Strain, D. M.; Chai, V. W.; Higgins, S.

    1979-01-01

    The energy Comsumption Computer Program was developed to simulate building heating and cooling loads and compute thermal and electric energy consumption and cost. This article reports on the new additional algorithms and modifications made in an effort to widen the areas of application. The program structure was rewritten accordingly to refine and advance the building model and to further reduce the processing time and cost. The program is noted for its very low cost and ease of use compared to other available codes. The accuracy of computations is not sacrificed however, since the results are expected to lie within + or - 10% of actual energy meter readings.