Well-being, health, and productivity improvement after an employee well-being intervention in large retail distribution centers.

PubMed

Rajaratnam, Augustine S; Sears, Lindsay E; Shi, Yuyan; Coberley, Carter R; Pope, James E

2014-12-01

To evaluate changes in well-being, biometric, and productivity indicators after a well-being intervention. Biometric and self-reported outcomes were assessed among 677 retail distribution center employees before and after a 6-month well-being intervention. Despite lower well-being at baseline compared to an independent random sample of workers, program participants' well-being, productivity, body mass index, systolic blood pressure, and total cholesterol improved significantly after the intervention, whereas the decline in diastolic blood pressure was not significant. Moreover, participants' specific transition across well-being segments over the intervention period demonstrated more improvement than decline. There is evidence that programs designed to improve well-being within a workforce can be used to significantly and positively impact employee health and productivity, which should result in reduced health care costs, improved employee productivity, and increased overall profitability.

An Analysis Of Additive Manufacturing Production Problems And Solutions

DTIC Science & Technology

2016-12-01

democratization of manufacturing (Hornick, 2015). AM has three distinct advantages over subtractive manufacturing : product customization, design flexibility...58 develops software and other technology solutions for the design , analysis, testing, manufacture , and validation of products (Diane Ryan, personal...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA MBA PROFESSIONAL REPORT AN ANALYSIS OF ADDITIVE MANUFACTURING PRODUCTION

Identification of flavour additives in tobacco products to develop a flavour library.

PubMed

Krüsemann, Erna Jz; Visser, Wouter F; Cremers, Johannes Wjm; Pennings, Jeroen LA; Talhout, Reinskje

2018-01-01

This study combines chemical analysis and flavour descriptions of flavour additives used in tobacco products, and provides a starting point to build an extensive library of flavour components, useful for product surveillance. Headspace gas chromatography-mass spectrometry (GC-MS) was used to compare 22 commercially available tobacco products (cigarettes and roll-your-own) expected to have a characterising flavour and 6 commercially available products not expected to have a characterising flavour with 5 reference products (natural tobacco leaves and research cigarettes containing no flavour additives). The flavour components naturally present in the reference products were excluded from components present in commercially available products containing flavour additives. A description of the remaining flavour additives was used for categorisation. GC-MS measurements of the 33 tobacco products resulted in an overview of 186 chemical compounds. Of these, 144 were solely present in commercially available products. These 144 flavour additives were described using 62 different flavour descriptors extracted from flavour databases, which were categorised into eight groups largely based on the definition of characterising flavours from the European Tobacco Product Directive: fruit, spice, herb, alcohol, menthol, sweet, floral and miscellaneous. We developed a method to identify and describe flavour additives in tobacco products. Flavour additives consist of single flavour compounds or mixtures of multiple flavour compounds, and different combinations of flavour compounds can cause a certain flavour. A flavour library helps to detect flavour additives that are characteristic for a certain flavour, and thus can be useful for regulation of flavours in tobacco and related products. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

[Productive activities and well-being among community-dwelling elderly].

PubMed

Okamoto, Hideaki

2009-10-01

This study examined the association between engagement in productive activities and well-being among community-dwelling elderly. Data for 576 older adults were obtained from a mail survey in Osaka City. The productive activities was measured with reference to three domains (paid work, unpaid work at home, and unpaid work outside the home) and the number of productive roles. Well-being was assessed by two measures: life satisfaction (LSIK) and self-rated health. The author used multivariate analyses with each of the two measures of well-being as dependent variables, and each of the productive activities as independent variables. The analyses were conducted separately for men and women, controlling for sociodemographic variables, IADL(instrumental activities of daily living) and social relationships. Multivariate analyses revealed the following findings. Paid work was positively associated with life satisfaction of women and self-rated health of men and women. Unpaid work at home was not significantly associated with life satisfaction or self-rated health for either men or women. However, unpaid work outside the home was related to higher scores for life satisfaction and self-rated health among women. The numbers of productive roles were positively associated with life satisfaction of women and self-rated health of men and women. Productive engagement was generally beneficial to older women's well-being except for unpaid work at home. Among men, only paid work out of the three activity domains and the number of productive roles were associated with better self-rated health. Public health policies and programs that bring older women into productive engagement outside the home may thus improve their well-being and generate benefits for communities.

78 FR 53486 - Addition of Round-Trip Mailer Product to the Competitive Product List

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-29

... POSTAL SERVICE Addition of Round-Trip Mailer Product to the Competitive Product List AGENCY... request with the Postal Regulatory Commission to add a product called ``Round-Trip Mailer'' to the...] filed with the Postal Regulatory Commission (Commission) a request to add a ``Round-Trip Mailer...

The role of cocoa as a cigarette additive: opportunities for product regulation.

PubMed

Sokol, Natasha A; Kennedy, Ryan David; Connolly, Gregory N

2014-07-01

The 2009 Family Smoking Prevention and Tobacco Control Act prohibited the use of characterizing flavors in cigarettes; however, some of these flavors are still used in cigarettes at varying levels. We reviewed tobacco industry internal documents to investigate the role of one of these flavors, cocoa, with the objective of understanding its relationship to sensory and risk perception, promotion of dependence, and enhancement of attractiveness and acceptability. We used the Legacy Tobacco Documents Library to identify documents relevant to our research questions. Initial search terms were generated following an examination of published literature on cocoa, other cigarette additives, and sensory and risk perception. Further research questions and search terms were generated based on review of documents generated from the initial search terms. Cocoa is widely applied to cigarettes and has been used by the tobacco industry as an additive since the early 20th century. Cocoa can alter the sensory properties of cigarette smoke, including by providing a more appealing taste and decreasing its harshness. The tobacco industry has experimented with manipulating cocoa levels as a means of achieving sensory properties that appeal to women and youth. Although cocoa is identified as a flavor on tobacco industry Web sites, it may serve other sensory purposes in cigarettes as well. Eliminating cocoa as an additive from tobacco products may affect tobacco product abuse liability by altering smokers' perceptions of product risk, and decreasing product appeal, especially among vulnerable populations. © The Author 2014. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Chitosan multiple addition enhances laccase production from Trametes versicolor.

PubMed

Adekunle, Abiodun Emmanuel; Wang, Feng; Hu, Jianhua; Ma, Anzhou; Guo, Chen; Zhuang, Guoqiang; Liu, Chun-Zhao

2015-10-01

Chitosan multiple addition strategy was developed to improve laccase production from Trametes versicolor cultures. The optimized multiple addition strategy was carried out by two-time addition of 0.1 g L(-1) chitosan to a 2-day-old culture media, with 24-h interval between the treatments. Under these conditions, laccase activity of 644.9 U l(-1) was achieved on the seventh day and laccase production was improved by 93.5 % higher than the control. Chitosan treatment increased reactive oxygen species generation and extracellular protein concentration in the treated mycelia. In contrast, the inducer inhibited the mycelia growth. The result of the quantitative reverse transcription polymerase chain reaction showed that the copy number of the laccase gene transcript increased by 16.7-fold in the treated mycelia relative to the control. This study provides insight into some of the intrinsic metabolic processes involved in the upregulation of laccase production in the presence of chitosan inducer in fungal culture.

Review of Well Operator Files for Hydraulically Fractured Oil and Gas Production Wells: Well Design and Construction Fact Sheet

EPA Pesticide Factsheets

EPA reviewed a statistically representative sample of oil and gas production wells reported by nine service companies to help understand the role of well design and construction practices preventing pathways for subsurface fluid movement.

Impact to Underground Sources of Drinking Water and Domestic Wells from Production Well Stimulation and Completion Practices in the Pavillion, Wyoming, Field.

PubMed

DiGiulio, Dominic C; Jackson, Robert B

2016-04-19

A comprehensive analysis of all publicly available data and reports was conducted to evaluate impact to Underground Sources of Drinking Water (USDWs) as a result of acid stimulation and hydraulic fracturing in the Pavillion, WY, Field. Although injection of stimulation fluids into USDWs in the Pavillion Field was documented by EPA, potential impact to USDWs at the depths of stimulation as a result of this activity was not previously evaluated. Concentrations of major ions in produced water samples outside expected levels in the Wind River Formation, leakoff of stimulation fluids into formation media, and likely loss of zonal isolation during stimulation at several production wells, indicates that impact to USDWs has occurred. Detection of organic compounds used for well stimulation in samples from two monitoring wells installed by EPA, plus anomalies in major ion concentrations in water from one of these monitoring wells, provide additional evidence of impact to USDWs and indicate upward solute migration to depths of current groundwater use. Detections of diesel range organics and other organic compounds in domestic wells <600 m from unlined pits used prior to the mid-1990s to dispose diesel-fuel based drilling mud and production fluids suggest impact to domestic wells as a result of legacy pit disposal practices.

Interlake production established using quantitative hydrocarbon well-log analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lancaster, J.; Atkinson, A.

1988-07-01

Production was established in a new pay zone of the basal Interlake Formation adjacent to production in Midway field in Williams County, North Dakota. Hydrocarbon saturation, which was computed using hydrocarbon well-log (mud-log) data, and computed permeability encouraged the operator to run casing and test this zone. By use of drilling rig parameters, drilling mud properties, hydrocarbon-show data from the mud log, drilled rock and porosity descriptions, and wireline log porosity, this new technique computes oil saturation (percent of porosity) and permeability to the invading filtrate, using the Darcy equation. The Leonardo Fee well was drilled to test the Devonianmore » Duperow, the Silurian upper Interlake, and the Ordovician Red River. The upper two objectives were penetrated downdip from Midway production and there were no hydrocarbon shows. It was determined that the Red River was tight, based on sample examination by well site personnel. The basal Interlake, however, liberated hydrocarbon shows that were analyzed by this new technology. The results of this evaluation accurately predicted this well would be a commercial success when placed in production. Where geophysical log analysis might be questionable, this new evaluation technique may provide answers to anticipated oil saturation and producibility. The encouraging results of hydrocarbon saturation and permeability, produced by this technique, may be largely responsible for the well being in production today.« less

Well-being improvement in a midsize employer: changes in well-being, productivity, health risk, and perceived employer support after implementation of a well-being improvement strategy.

PubMed

Hamar, Brent; Coberley, Carter; Pope, James E; Rula, Elizabeth Y

2015-04-01

To evaluate employee well-being change and associated change in productivity, health risk including biometrics, and workplace support over 2 years after implementation of a well-being improvement strategy. This was an employer case study evaluation of well-being, productivity (presenteeism, absenteeism, and job performance), health risk, and employer support across three employee assessment spanning 2 years. Employee well-being was compared with an independent sample of workers in the community. Well-being and job performance increased and presenteeism and health risk decreased significantly over the 2 years. Employee well-being started lower and increased to exceed community worker averages, approaching significance. Well-being improvement was associated with higher productivity across all measures. Increases in employer support for well-being were associated with improved well-being and productivity. This employer's well-being strategy, including a culture supporting well-being, was associated with improved health and productivity.

Well-Production Data and Gas-Reservoir Heterogeneity -- Reserve Growth Applications

USGS Publications Warehouse

Dyman, Thaddeus S.; Schmoker, James W.

2003-01-01

Oil and gas well production parameters, including peakmonthly production (PMP), peak-consecutive-twelve month production (PYP), and cumulative production (CP), are tested as tools to quantify and understand the heterogeneity of reservoirs in fields where current monthly production is 10 percent or less of PMP. Variation coefficients, defined as VC= (F5-F95)/F50, where F5, F95, and F50 are the 5th, 95th, and 50th (median) fractiles of a probability distribution, are calculated for peak and cumulative production and examined with respect to internal consistency, type of production parameter, conventional versus unconventional accumulations, and reservoir depth. Well-production data for this study were compiled for 69 oil and gas fields in the Lower Pennsylvanian Morrow Formation of the Anadarko Basin, Oklahoma. Of these, 47 fields represent production from marine clastic facies. The Morrow data were supplemented by data from the Upper Cambrian and Lower Ordovician Arbuckle Group, Middle Ordovician Simpson Group, Middle Pennsylvanian Atoka Formation, and Silurian and Lower Devonian Hunton Group of the Anadarko Basin, one large gas field in Upper Cretaceous reservoirs of north-central Montana (Bowdoin field), and three areas of the Upper Devonian and Lower Mississippian Bakken Formation continuous-type (unconventional) oil accumulation in the Williston Basin, North Dakota and Montana. Production parameters (PMP, PYP, and CP) measure the net result of complex geologic, engineering, and economic processes. Our fundamental hypothesis is that well-production data provide information about subsurface heterogeneity in older fields that would be impossible to obtain using geologic techniques with smaller measurement scales such as petrographic, core, and well-log analysis. Results such as these indicate that quantitative measures of production rates and production volumes of wells, expressed as dimensionless variation coefficients, are potentially valuable tools for

STEADY-STATE DESIGN OF VERTICAL WELLS FOR LIQUIDS ADDITION AT BIOREACTOR LANDFILLS

EPA Science Inventory

This paper presents design charts that a landfill engineer can use for the design of a vertical well system for liquids addition at bioreactor landfills. The flow rate and lateral and vertical zones of impact of a vertical well were estimated as a function of input variables su...

Increasing meat product functionality by the addition of milled flaxseed Linum usitatissimum.

PubMed

Zając, Marzena; Kulawik, Piotr; Tkaczewska, Joanna; Migdał, Władysław; Pustkowiak, Henryk

2017-07-01

Functional meat products are still rare on the market because it is difficult to incorporate new ingredients and obtain both a healthy and acceptable product. Flaxseed is known for its beneficial properties and, in the present study, it was used as an ingredient in the production of homogenised and liver sausages (0%, 5% and 10% flaxseed addition). Homogenised and liver sausages with the addition of 5% flaxseed were given the highest scores by the consumers, although the colour changed with the addition of flaxseed. The spreadability and hardness of the liver sausages increased with the addition of flaxseed, whereas the texture of homogenised sausages did not change. Addition of flaxseed improved the fatty acids profile from a health point of view for both products, as a result of increasing n-3 fatty acids and overall polyunsaturated fatty acids content. Values for thiobarbituric acid reactive substances were higher in products with flaxseed and were observed to increase during storage. The results of the present study indicate that it is possible to obtain products that are acceptable by consumers and, at the same time, are more healthy. A high level of α-linolenic acid in the sausages at a level of addition of 5% allows the product to be labelled with information regarding their high omega-3 fatty acid content. However, those products are more susceptible to oxidation. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

Additive manufacturing techniques for the production of tissue engineering constructs.

PubMed

Mota, Carlos; Puppi, Dario; Chiellini, Federica; Chiellini, Emo

2015-03-01

'Additive manufacturing' (AM) refers to a class of manufacturing processes based on the building of a solid object from three-dimensional (3D) model data by joining materials, usually layer upon layer. Among the vast array of techniques developed for the production of tissue-engineering (TE) scaffolds, AM techniques are gaining great interest for their suitability in achieving complex shapes and microstructures with a high degree of automation, good accuracy and reproducibility. In addition, the possibility of rapidly producing tissue-engineered constructs meeting patient's specific requirements, in terms of tissue defect size and geometry as well as autologous biological features, makes them a powerful way of enhancing clinical routine procedures. This paper gives an extensive overview of different AM techniques classes (i.e. stereolithography, selective laser sintering, 3D printing, melt-extrusion-based techniques, solution/slurry extrusion-based techniques, and tissue and organ printing) employed for the development of tissue-engineered constructs made of different materials (i.e. polymeric, ceramic and composite, alone or in combination with bioactive agents), by highlighting their principles and technological solutions. Copyright © 2012 John Wiley & Sons, Ltd.

78 FR 77384 - DSM Nutritional Products; Filing of Food Additive Petition (Animal Use)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-23

.... FDA-2013-F-1540] DSM Nutritional Products; Filing of Food Additive Petition (Animal Use) AGENCY: Food... (FDA) is announcing that DSM Nutritional Products has filed a petition proposing that the food additive...)), notice is given that a food additive petition (FAP 2277) has been filed by DSM Nutritional Products, 45...

Comparing the contributions of well-being and disease status to employee productivity.

PubMed

Gandy, William M; Coberley, Carter; Pope, James E; Wells, Aaron; Rula, Elizabeth Y

2014-03-01

To compare employee overall well-being to chronic disease status, which has a long-established relationship to productivity, as relative contributors to on-the-job productivity. Data from two annual surveys of three companies were used in longitudinal analyses of well-being as a predictor of productivity level and productivity change among 2629 employees with diabetes or without any chronic conditions. Well-being was the most significant predictor of productivity cross-sectionally in a model that included disease status and demographic characteristics. Longitudinally, changes in well-being contributed to changes in productivity above and beyond what could be explained by the presence of chronic disease or other fixed characteristics. These findings support the use of well-being as the broader framework for understanding, explaining, and improving employee productivity in both the healthy and those with disease.

30 CFR 250.1151 - How often must I conduct well production tests?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How often must I conduct well production tests... Requirements Well Tests and Surveys § 250.1151 How often must I conduct well production tests? (a) You must conduct well production tests as shown in the following table: You must conduct: And you must submit to...

Effect of Periodic Water Addition on Citric Acid Production in Solid State Fermentation

NASA Astrophysics Data System (ADS)

Utpat, Shraddha S.; Kinnige, Pallavi T.; Dhamole, Pradip B.

2013-09-01

Water addition is one of the methods used to control the moisture loss in solid state fermentation (SSF). However, none of the studies report the timing of water addition and amount of water to be added in SSF. Therefore, this work was undertaken with an objective to evaluate the performance of periodic water addition on citric acid production in SSF. Experiments were conducted at different moistures (50-80 %) and temperatures (30-40 °C) to simulate the conditions in a fermenter. Citric acid production by Aspergillus niger (ATCC 9029) using sugarcane baggase was chosen as a model system. Based on the moisture profile, citric acid and sugar data, a strategy was designed for periodic addition of water. Water addition at 48, 96, 144 and 192 h enhanced the citric acid production by 62 % whereas water addition at 72, 120, and 168 h increased the citric acid production by just 17 %.

Review of Well Operator Files for Hydraulically Fractured Oil and Gas Production Wells: Hydraulic Fracturing Operations

EPA Pesticide Factsheets

EPA conducted a survey of oil and gas production wells hydraulically fractured by nine oil and gas service companies in the United States during 2009 and 2010. This is the second well file review report.

A test strategy for the assessment of additive attributed toxicity of tobacco products.

PubMed

Kienhuis, Anne S; Staal, Yvonne C M; Soeteman-Hernández, Lya G; van de Nobelen, Suzanne; Talhout, Reinskje

2016-08-01

The new EU Tobacco Product Directive (TPD) prohibits tobacco products containing additives that are toxic in unburnt form or that increase overall toxicity of the product. This paper proposes a strategy to assess additive attributed toxicity in the context of the TPD. Literature was searched on toxicity testing strategies for regulatory purposes from tobacco industry and governmental institutes. Although mainly traditional in vivo testing strategies have been applied to assess toxicity of unburnt additives and increases in overall toxicity of tobacco products due to additives, in vitro tests combined with toxicogenomics and validated using biomarkers of exposure and disease are most promising in this respect. As such, tests are needed that are sensitive enough to assess additive attributed toxicity above the overall toxicity of tobacco products, which can associate assay outcomes to human risk and exposure. In conclusion, new, sensitive in vitro assays are needed to conclude whether comparable testing allows for assessment of small changes in overall toxicity attributed to additives. A more pragmatic approach for implementation on a short-term is mandated lowering of toxic emission components. Combined with risk assessment, this approach allows assessment of effectiveness of harm reduction strategies, including banning or reducing of additives. Copyright © 2016 Elsevier Ltd. All rights reserved.

78 FR 77384 - DSM Nutritional Products; Filing of Food Additive Petition (Animal Use)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-23

.... FDA-2013-F-1539] DSM Nutritional Products; Filing of Food Additive Petition (Animal Use) AGENCY: Food... (FDA) is announcing that DSM Nutritional Products has filed a petition proposing that the food additive... U.S.C. 348(b)(5)), notice is given that a food additive petition (FAP 2276) has been filed by DSM...

The evaluation of the optimization design and application effect of same-well-injection-production technique’s injection-production circulatory system

NASA Astrophysics Data System (ADS)

Guoxing, Zheng; Minghu, Jiang; Hongliang, Gong; Nannan, Zhang; Jianguang, Wei

2018-02-01

According to basic principles of combining series of strata and demands of same-well injection-production technique, the optimization designing method of same-well injection-production technique’s injection-production circulatory system is given. Based on oil-water two-phase model with condition of arbitrarily well network, a dynamic forecast method for the application of same-well injection-production reservoir is established with considering the demands and capacity of same-well injection-production technique, sample wells are selected to launch the forecast evaluation and analysis of same-well injection-production reservoir application’s effect. Results show: single-test-well composite water cut decreases by 4.7% and test-well-group composite water cut decreases by 1.56% under the condition of basically invariant ground water injection rate. The method provides theoretical support for the proof of same-well injection-production technique’s reservoir development improving effect and further tests.

77 FR 71750 - DSM Nutritional Products; Filing of Food Additive Petition (Animal Use)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-04

.... FDA-2012-F-1100] DSM Nutritional Products; Filing of Food Additive Petition (Animal Use) AGENCY: Food... (FDA) is announcing that DSM Nutritional Products has filed a petition proposing that the food additive...) (21 U.S.C. 348(b)(5))), notice is given that a food additive petition (FAP 2273) has been filed by DSM...

17 CFR 41.25 - Additional conditions for trading for security futures products.

Code of Federal Regulations, 2011 CFR

2011-04-01

... trading for security futures products. 41.25 Section 41.25 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SECURITY FUTURES PRODUCTS Requirements and Standards for Listing Security Futures Products § 41.25 Additional conditions for trading for security futures products. (a) Common...

17 CFR 41.25 - Additional conditions for trading for security futures products.

Code of Federal Regulations, 2012 CFR

2012-04-01

... trading for security futures products. 41.25 Section 41.25 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SECURITY FUTURES PRODUCTS Requirements and Standards for Listing Security Futures Products § 41.25 Additional conditions for trading for security futures products. (a) Common...

17 CFR 41.25 - Additional conditions for trading for security futures products.

Code of Federal Regulations, 2013 CFR

2013-04-01

... trading for security futures products. 41.25 Section 41.25 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SECURITY FUTURES PRODUCTS Requirements and Standards for Listing Security Futures Products § 41.25 Additional conditions for trading for security futures products. (a) Common...

17 CFR 41.25 - Additional conditions for trading for security futures products.

Code of Federal Regulations, 2014 CFR

2014-04-01

... trading for security futures products. 41.25 Section 41.25 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION (CONTINUED) SECURITY FUTURES PRODUCTS Requirements and Standards for Listing Security Futures Products § 41.25 Additional conditions for trading for security futures products. (a...

Basic Study on Production Well Integrity for Methane Hydrate Development

NASA Astrophysics Data System (ADS)

Kakumoto, M.; Yoneda, J.; Katagiri, J.; Tenma, N.; Aoki, K.

2014-12-01

Methane Hydrate (MH) exist as an ice-like crystal under low-temperature and high-pressure condition, and it has gathering attention as a non-conventional natural gas resource. Depressurization method is a method to reduce the bottom hole pressure by submersible pump lowering water level in the production well, and gas and water is recovered by MH dissociation at the in situ. During the depressurization operation, consolidation and deformation of sediment occurs because of increase of effective stress by depressurization and changes in the soil structure by MH dissociation. Then consolidation and deformation of sediment makes negative friction between the production well and sediment, and large stress is occur in casing. Therefore there is concern that it may cause compression failure and shear failure of the production well. For safe MH development, it is necessary to grasp the deformation and stress vicinity of the production well. At first, we conducted push-out test to get friction strength between the different materials simulated the well and sediment. And we have done numerical analysis for integrity using by these data. The results of numerical analysis showed that the large deformation of sediment occur around the depressurization zone, and for the well, the large tensile stress in the vertical direction occur the upper vicinity of the depressurization zone.This study was financially supported by the Research Consortium for Methane Hydrate Resources in Japan (MH21 Research Consortium) planned by Ministry of Economy, Trade and Industry (METI). The authors thank the entire personnel related to MH21 Research Consortium.

SETTING A GOAL FOR TPH THAT ELIMINATES FREE PRODUCT IN WELLS

EPA Science Inventory

The U.S. EPA expects that remedial action at UST sites will reduce free product in monitoring wells to the maximum extent practicable. How much active treatment is necessary to ensure that free product will not accumulate in a monitoring well? The concentration of TPH that will...

Enhanced photo-fermentative H2 production using Rhodobacter sphaeroides by ethanol addition and analysis of soluble microbial products

PubMed Central

2014-01-01

Background Biological fermentation routes can provide an environmentally friendly way of producing H2 since they use renewable biomass as feedstock and proceed under ambient temperature and pressure. In particular, photo-fermentation has superior properties in terms of achieving high H2 yield through complete degradation of substrates. However, long-term H2 production data with stable performance is limited, and this data is essential for practical applications. In the present work, continuous photo-fermentative H2 production from lactate was attempted using the purple non-sulfur bacterium, Rhodobacter sphaeroides KD131. As a gradual drop in H2 production was observed, we attempted to add ethanol (0.2% v/v) to the medium. Results As continuous operation went on, H2 production was not sustained and showed a negligible H2 yield (< 0.5 mol H2/mol lactateadded) within two weeks. Electron balance analysis showed that the reason for the gradual drop in H2 production was ascribed to the increase in production of soluble microbial products (SMPs). To see the possible effect of ethanol addition, a batch test was first conducted. The presence of ethanol significantly increased the H2 yield from 1.15 to 2.20 mol H2/mol lactateadded, by suppressing the production of SMPs. The analysis of SMPs by size exclusion chromatography showed that, in the later period of fermentation, more than half of the low molecular weight SMPs (< 1 kDa) were consumed and used for H2 production when ethanol had been added, while the concentration of SMPs continuously increased in the absence of ethanol. It was found that the addition of ethanol facilitated the utilization of reducing power, resulting in an increase in the cellular levels of NAD+ and NADP+. In continuous operation, ethanol addition was effective, such that stable H2 production was attained with an H2 yield of 2.5 mol H2/mol lactateadded. Less than 15% of substrate electrons were used for SMP production, whereas 35% were used in

THE COMBINED CARCINOGENIC RISK FOR EXPOSURE TO MIXTURES OF DRINKING WATER DISINFECTION BY-PRODUCTS MAY BE LESS THAN ADDITIVE

EPA Science Inventory

The Combined Carcinogenic Risk for Exposure to Mixtures of Drinking Water Disinfection By-Products May be Less Than Additive

Risk assessment methods for chemical mixtures in drinking water are not well defined. Current default risk assessments for chemical mixtures assume...

Additive Manufacturing and Casting Technology Comparison: Mechanical Properties, Productivity and Cost Benchmark

NASA Astrophysics Data System (ADS)

Vevers, A.; Kromanis, A.; Gerins, E.; Ozolins, J.

2018-04-01

The casting technology is one of the oldest production technologies in the world but in the recent years metal additive manufacturing also known as metal 3D printing has been evolving with huge steps. Both technologies have capabilities to produce parts with internal holes and at first glance surface roughness is similar for both technologies, which means that for precise dimensions parts have to be machined in places where precise fit is necessary. Benchmark tests have been made to find out if parts which are produced with metal additive manufacturing can be used to replace parts which are produced with casting technology. Most of the comparative tests have been made with GJS-400-15 grade which is one of the most popular cast iron grades. To compare mechanical properties samples have been produced using additive manufacturing and tested for tensile strength, hardness, surface roughness and microstructure and then the results have been compared with the samples produced with casting technology. In addition, both technologies have been compared in terms of the production time and production costs to see if additive manufacturing is competitive with the casting technology. The original paper has been written in the Latvian language as part of the Master Thesis within the framework of the production technology study programme at Riga Technical University.

Innovations in value-addition of edible meat by-products.

PubMed

Toldrá, Fidel; Aristoy, M-Concepción; Mora, Leticia; Reig, Milagro

2012-11-01

While muscle foods are the more commonly consumed portion of an animal, meat by-products such as the entrails and internal organs are also widely consumed. Considered high-priced delicacies or waste material to be tossed away, the use and value of offal-edible and inedible meat by-products depend entirely on the culture and country in question. The skin, blood, bones, meat trimmings, fatty tissues, horns, hoofs, feet, skull, and internal organs of harvested animals comprise a wide variety of products including human or pet food or processed materials in animal feed, fertilizer, or fuel. Industry is using science and innovation to add value to animal by-products far beyond its usual profitability. Regardless of the final product's destination, it is still necessary to employ the most up-to-date and effective tools to analyze these products for nutritional properties, to search for key active molecules in nutrition like bioactive peptides, food safety (antimicrobial peptides), medicine, cosmetics or other fields, to develop new technological applications and to continue innovation towards advanced value-addition of meat by-products. Copyright © 2012 Elsevier Ltd. All rights reserved.

Elevations of bench marks, observation wells, and production wells at Mather Air Force Base, Sacramento County, California, 1988

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ikehara, M.E.; McCaffrey, W.F.; Williams, J.S.

A U.S. Geological Survey report is presented giving information on the elevations of bench marks, observation wells, and production wells at Mather Air Force Base, Sacramento County, California, 1988.

Effect of additives on mineral trioxide aggregate setting reaction product formation.

PubMed

Zapf, Angela M; Chedella, Sharath C V; Berzins, David W

2015-01-01

Mineral trioxide aggregate (MTA) sets via hydration of calcium silicates to yield calcium silicate hydrates and calcium hydroxide (Ca[OH]2). However, a drawback of MTA is its long setting time. Therefore, many additives have been suggested to reduce the setting time. The effect those additives have on setting reaction product formation has been ignored. The objective was to examine the effect additives have on MTA's setting time and setting reaction using differential scanning calorimetry (DSC). MTA powder was prepared with distilled water (control), phosphate buffered saline, 5% calcium chloride (CaCl2), 3% sodium hypochlorite (NaOCl), or lidocaine in a 3:1 mixture and placed in crucibles for DSC evaluation. The setting exothermic reactions were evaluated at 37°C for 8 hours to determine the setting time. Separate samples were stored and evaluated using dynamic DSC scans (37°C→640°C at10°C/min) at 1 day, 1 week, 1 month, and 3 months (n = 9/group/time). Dynamic DSC quantifies the reaction product formed from the amount of heat required to decompose it. Thermographic peaks were integrated to determine enthalpy, which was analyzed with analysis of variance/Tukey test (α = 0.05). Isothermal DSC identified 2 main exothermal peaks occurring at 44 ± 12 and 343 ± 57 minutes for the control. Only the CaCl2 additive was an accelerant, which was observed by a greater exothermic peak at 101 ± 11 minutes, indicating a decreased setting time. The dynamic DSC scans produced an endothermic peak around 450°C-550°C attributed to Ca(OH)2 decomposition. The use of a few additives (NaOCl and lidocaine) resulted in significantly less Ca(OH)2 product formation. DSC was used to discriminate calcium hydroxide formation in MTA mixed with various additives and showed NaOCl and lidocaine are detrimental to MTA reaction product formation, whereas CaCl2 accelerated the reaction. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Examining relationships between multiple health risk behaviors, well-being, and productivity.

PubMed

Evers, Kerry E; Castle, Patricia H; Prochaska, James O; Prochaska, Janice M

2014-06-01

Traditionally, the concept of health promotion has emphasized the reduction of health risk behaviors to reduce disease and impairment. Well-being research expands this focus to include positive constructs such as thriving, productivity, life-evaluation, and emotional and physical health. The objective of the present study was to examine the relationships between health risk behaviors and specific measures of individual well-being. Participants (N = 790) from 49 states completed a one-time online assessment that included the Life-Evaluation Index, Emotional and Physical Health Ladders, the Health Risk Intervention Assessment, and the Work Productivity and Activity Improvement Questionnaire for General Health. Life Evaluation and physical and emotional health were all inversely related to the number of health risk behaviors, with higher well-being scores associated with lower number of risk behaviors. Across the three Life Evaluation categories (Suffering, Struggling, and Thriving) the number of health risk behaviors decreased, productivity loss decreased, and emotional and physical health increased. The results add to previous research on how reducing multiple health risk behaviors can be combined with well-being, i.e., an emphasis on increasing life-evaluation, emotional and physical health, better functioning, and productivity.

Publicity campaign, wellness event raise awareness of Michigan home health company, products.

PubMed

2007-01-01

HoMedics, a home healthcare and wellness company in Commerce Township, MI, had a problem. As a leading manufacturer of personal wellness and home healthcare products, its product line was constantly evolving with new and innovative technological advances. But with so many rapid changes, HoMedics had trouble educating the media about its new product lines quickly enough. The solution? A multiphase public relations campaign.

Qualitative identification of permitted and non-permitted colour additives in food products.

PubMed

Harp, Bhakti Petigara; Miranda-Bermudez, Enio; Baron, Carolina I; Richard, Gerald I

2012-01-01

Colour additives are dyes, pigments or other substances that can impart colour when added or applied to food, drugs, cosmetics, medical devices, or the human body. The substances must be pre-approved by the US Food and Drug Administration (USFDA) and listed in Title 21 of the US Code of Federal Regulations before they may be used in products marketed in the United States. Some also are required to be batch certified by the USFDA prior to their use. Both domestic and imported products sold in interstate commerce fall under USFDA jurisdiction, and the USFDA's district laboratories use a combination of analytical methods for identifying or confirming the presence of potentially violative colour additives. We have developed a qualitative method for identifying 17 certifiable, certification exempt, and non-permitted colour additives in various food products. The method involves extracting the colour additives from a product and isolating them from non-coloured components with a C(18) Sep-Pak cartridge. The colour additives are then separated and identified by liquid chromatography (LC) with photodiode array detection, using an Xterra RP18 column and gradient elution with aqueous ammonium acetate and methanol. Limits of detection (LODs) ranged from 0.02 to 1.49 mg/l. This qualititative LC method supplements the visible spectrophotometric and thin-layer chromatography methods currently used by the USFDA's district laboratories and is less time-consuming and requires less solvent compared to the other methods. The extraction step in the new LC method is a simple and an efficient process that can be used for most food types.

15 CFR 713.4 - Advance declaration requirements for additionally planned production, processing, or consumption...

Code of Federal Regulations, 2010 CFR

2010-01-01

... INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 2 CHEMICALS § 713.4 Advance declaration requirements for additionally planned production... additionally planned production, processing, or consumption of Schedule 2 chemicals. 713.4 Section 713.4...

15 CFR 713.4 - Advance declaration requirements for additionally planned production, processing, or consumption...

Code of Federal Regulations, 2011 CFR

2011-01-01

... INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 2 CHEMICALS § 713.4 Advance declaration requirements for additionally planned production... additionally planned production, processing, or consumption of Schedule 2 chemicals. 713.4 Section 713.4...

Sodium-Reduced Meat and Poultry Products Contain a Significant Amount of Potassium from Food Additives.

PubMed

Parpia, Arti Sharma; Goldstein, Marc B; Arcand, JoAnne; Cho, France; L'Abbé, Mary R; Darling, Pauline B

2018-05-01

-sodium-reduced counterparts (mean difference [95% CI]: 486 [334-638]; P<0.001). The amounts of phosphorus and protein, as well as the frequency of phosphorus additives appearing on the product label ingredient list, did not significantly differ between the two groups. Potassium additives are frequently added to sodium-reduced MPPs in amounts that significantly contribute to the potassium load for patients with impaired renal handling of potassium caused by chronic kidney disease and certain medications. Patients requiring potassium restriction should be counseled to be cautious regarding the potassium content of sodium-reduced MPPs and encouraged to make food choices accordingly. Copyright © 2018 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

Predicting acute and chronic effects of wood preservative products in Daphnia magna and Pseudokirchneriella subcapitata based on the concept of concentration addition.

PubMed

Coors, Anja; Weisbrod, Barbara; Schoknecht, Ute; Sacher, Frank; Kehrer, Anja

2014-02-01

The current European legislation requires that combined effects of the active substances and any substance of concern contained in biocidal products are taken into account in environmental risk assessment. The hypothesis whether the consideration of active substances together with all formulation additives that are labeled as presenting an environmental hazard is sufficient for a reliable environmental risk assessment was tested in the present study by investigating 3 wood preservative products. Relevant single substances in the products, some of their generic mixtures, the biocidal products themselves, and aqueous eluates prepared from the products (representing potential environmental mixtures) were tested for effects on algal growth and Daphnia acute immobilization as well as reproduction. Predictions for the products and the eluates were based on the concept of concentration addition and were mostly found to provide reliable or at least protective estimates for the observed acute and chronic toxicity of the mixtures. The mixture toxicity considerations also indicated that the toxicity of each product was dominated by just 1 of the components, and that assessments based only on the dominating substance would be similarly protective as a full-mixture risk assessment. Yet, there remained uncertainty in some cases that could be related to the toxicity of transformation products, the impact of unidentified formulation additives, or synergistic interaction between active substances and formulation additives. © 2013 SETAC.

Comparison of Microbial Community Compositions of Injection and Production Well Samples in a Long-Term Water-Flooded Petroleum Reservoir

PubMed Central

Ren, Hong-Yan; Zhang, Xiao-Jun; Song, Zhi-yong; Rupert, Wieger; Gao, Guang-Jun; Guo, Sheng-xue; Zhao, Li-Ping

2011-01-01

Water flooding plays an important role in recovering oil from depleted petroleum reservoirs. Exactly how the microbial communities of production wells are affected by microorganisms introduced with injected water has previously not been adequately studied. Using denaturing gradient gel electrophoresis (DGGE) approach and 16S rRNA gene clone library analysis, the comparison of microbial communities is carried out between one injection water and two production waters collected from a working block of the water-flooded Gudao petroleum reservoir located in the Yellow River Delta. DGGE fingerprints showed that the similarities of the bacterial communities between the injection water and production waters were lower than between the two production waters. It was also observed that the archaeal composition among these three samples showed no significant difference. Analysis of the 16S rRNA gene clone libraries showed that the dominant groups within the injection water were Betaproteobacteria, Gammaproteobacteria and Methanomicrobia, while the dominant groups in the production waters were Gammaproteobacteria and Methanobacteria. Only 2 out of 54 bacterial operational taxonomic units (OTUs) and 5 out of 17 archaeal OTUs in the injection water were detected in the production waters, indicating that most of the microorganisms introduced by the injection water may not survive to be detected in the production waters. Additionally, there were 55.6% and 82.6% unique OTUs in the two production waters respectively, suggesting that each production well has its specific microbial composition, despite both wells being flooded with the same injection water. PMID:21858049

Results of well-bore flow logging for six water-production wells completed in the Santa Fe Group aquifer system, Albuquerque, New Mexico, 1996-98

USGS Publications Warehouse

Thorn, Conde R.

2000-01-01

Over the last several years, an improved conceptual understanding of the aquifer system in the Albuquerque area, New Mexico, has lead to better knowledge about the location and extent of the aquifer system. This information will aid with the refinement of ground-water simulation and with the location of sites for future water-production wells. With an impeller-type flowmeter, well-bore flow was logged under pumping conditions along the screened interval of the well bore in six City of Albuquerque water-production wells: the Ponderosa 3, Love 6, Volcano Cliffs 1, Gonzales 2, Zamora 2, and Gonzales 3 wells. From each of these six wells, a well-bore flow log was collected that represents the cumulative upward well-bore flow. Evaluation of the well-bore flow log for each well allowed delineation of the more productive zones supplying water to the well along the logged interval. Yields from the more productive zones in the six wells ranged from about 70 to 880 gallons per minute. The lithology of these zones is predominantly gravel and sand with varying amounts of sandy clay.

Production tolerance of additive manufactured polymeric objects for clinical applications.

PubMed

Braian, Michael; Jimbo, Ryo; Wennerberg, Ann

2016-07-01

To determine the production tolerance of four commercially available additive manufacturing systems. By reverse engineering annex A and B from the ISO_12836;2012, two geometrical figures relevant to dentistry was obtained. Object A specifies the measurement of an inlay-shaped object and B a multi-unit specimen to simulate a four-unit bridge model. The objects were divided into x, y and z measurements, object A was divided into a total of 16 parameters and object B was tested for 12 parameters. The objects were designed digitally and manufactured by professionals in four different additive manufacturing systems; each system produced 10 samples of each objects. For object A, three manufacturers presented an accuracy of <100μm and one system showed an accuracy of <20μm. For object B, all systems presented an accuracy of <100μm, and most parameters were <40μm. The standard deviation for most parameters were <40μm. The growing interest and use of intra-oral digitizing systems stresses the use of computer aided manufacturing of working models. The additive manufacturing techniques has the potential to help us in the digital workflow. Thus, it is important to have knowledge about production accuracy and tolerances. This study presents a method to test additive manufacturing units for accuracy and repeatability. Copyright © 2016 The Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

Regulation of docosahexaenoic acid production by Schizochytrium sp.: effect of nitrogen addition.

PubMed

Ren, Lu-Jing; Sun, Li-Na; Zhuang, Xiao-Yan; Qu, Liang; Ji, Xiao-Jun; Huang, He

2014-05-01

Docosahexaenoic acid (DHA) percentage in total fatty acids (TFAs) is an important index in DHA microbial production. In this study, the change of DHA percentage in response to fermentation stages and the strategies to increase DHA percentage were investigated. Two kinds of conventional nitrogen sources, monosodium glutamate (MSG) and ammonium sulfate (AS), were tested to regulate DHA synthesis. Results showed that MSG addition could accelerate the substrate consumption rate but inhibit lipid accumulation, while AS addition could increase DHA percentage in TFAs effectively but extend fermentation period slightly. Finally, the AS addition strategy was successfully applied in 7,000-L fermentor and DHA percentage in TFAs and DHA yield reached 46.06 % and 18.48 g/L, which was 19.54 and 17.41 % higher than that of no-addition strategy. This would provide guidance for the large-scale production of the other similar polyunsaturated fatty acid, and give insight into the nitrogen metabolism in oil-producing microorganisms.

77 FR 58567 - Information Collection Activities: Well Control and Production Safety Training, Submitted for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-21

...-0006; OMB Number 1014-0008] Information Collection Activities: Well Control and Production Safety... requirements in the regulations under Subpart O, ``Well Control and Production Safety Training.'' This notice... and Production Safety Training. OMB Control Number: 1014-0008. Abstract: The Outer Continental Shelf...

Additive Manufactured Product Integrity

NASA Technical Reports Server (NTRS)

Waller, Jess; Wells, Doug; James, Steve; Nichols, Charles

2017-01-01

NASA is providing key leadership in an international effort linking NASA and non-NASA resources to speed adoption of additive manufacturing (AM) to meet NASA's mission goals. Participants include industry, NASA's space partners, other government agencies, standards organizations and academia. Nondestructive Evaluation (NDE) is identified as a universal need for all aspects of additive manufacturing.

Prediction of gas production using well logs, Cretaceous of north-central Montana

USGS Publications Warehouse

Hester, T.C.

1999-01-01

Cretaceous gas sands underlie much of east-central Alberta and southern Saskatchewan, eastern Montana, western North Dakota, and parts of South Dakota and Wyoming. Estimates of recoverable biogenic methane from these rocks in the United States are as high as 91 TCF. In northern Montana, current production is localized around a few major structural features, while vast areas in between these structures are not being exploited. Although the potential for production exists, the lack of commercial development is due to three major factors: 1) the lack of pipeline infrastructure; 2) the lack of predictable and reliable rates of production; and 3) the difficulty in recognizing and selecting potentially productive gas-charged intervals. Unconventional (tight), continuous-type reservoirs, such as those in the Cretaceous of the northern Great Plains, are not well suited for conventional methods of formation evaluation. Pay zones frequently consist only of thinly laminated intervals of sandstone, silt, shale stringers, and disseminated clay. Potential producing intervals are commonly unrecognizable on well logs, and thus are overlooked. To aid in the identification and selection of potential producing intervals, a calibration system is developed here that empirically links the 'gas effect' to gas production. The calibration system combines the effects of porosity, water saturation, and clay content into a single 'gas-production index' (GPI) that relates the in-situ rock with production potential. The fundamental method for isolating the gas effect for calibration is a crossplot of neutron porosity minus density porosity vs gamma-ray intensity. Well-log and gas-production data used for this study consist of 242 perforated intervals from 53 gas-producing wells. Interval depths range from about 250 to 2400 ft. Gas volumes in the peak calendar year of production range from about 4 to 136 MMCF. Nine producing formations are represented. Producing-interval data show that porosity

Performance of casings in Cerro Prieto production wells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dominguez A, B.; Vital B, F.; Bermejo M, F.

A careful evaluation of different production casings used at Cerro Prieto from 1964 to date has shown that the following casings have yielded particularly impressive results: 7 5/8-in. diameter, J-55, 26 lb/ft; 7 5/8-in. diameter, K-55, 45.3 lb/ft; and 5-in. diameter, K-55, 23.2 lb/ft. These casings differ from others of the same diameter but lighter weight which were also used at the field. The results are favorable in spite of severe construction problems, especially the loss of circulation during cementing operations, which we encountered in some of the wells where these casings were used. The use of gravity-fed fine sandmore » as packing material and the arrangement of the production and intermediate casings were important in avoiding damage due to tension-compression stresses and, above all, damage due to internal or external corrosion over time. This situation is clearly evidenced if we compare the damage to the above casings with that experienced by grade N-80 production casings, especially in a corrosive environment.« less

15 CFR 714.3 - Advance declaration requirements for additionally planned production of Schedule 3 chemicals.

Code of Federal Regulations, 2011 CFR

2011-01-01

... COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 3 CHEMICALS § 714.3 Advance declaration requirements for additionally planned production of Schedule 3 chemicals. (a) Declaration... additionally planned production of Schedule 3 chemicals. 714.3 Section 714.3 Commerce and Foreign Trade...

Effect of the addition of fatty by-products from the refining of vegetable oil on methane production in co-digestion.

PubMed

Torrijos, M; Sousbie, P; Badey, L; Bosque, F; Steyer, J P

2012-01-01

The purpose of this work was to investigate the effects of the addition of by-products from the refining of vegetable oil on the behavior of co-digestion reactors treating a mixture of grass, cow dung and fruit and vegetable waste. Three by-products were used: one soapstock, one used winterization earth and one skimming of aeroflotation of the effluents. Three 15 l reactors were run in parallel and fed five times a week. In a first phase of 4 weeks, the three reactors were fed with the co-digestion substrates alone (grass, cow dung and fruit and vegetable waste) at an organic loading rate (OLR) of 1.5 g VS/kg d (VS: volatile solids). Then, a different by-product from the refining of oil was added to the feed of each reactor at an OLR of 0.5 g VS/kg d, generating a 33% increase in the OLR. The results show that the addition of by-products from the refining of oil is an efficient way of increasing the methane production of co-digestion reactors thanks to high methane yield of such by-products (0.69-0.77 l CH(4)/g VS loaded). In fact, in this work, it was possible to raise the methane production of the reactors by about 60% through a 33% increase in the OLR thanks to the addition of the by-products from the refining of vegetable oil.

Dissection of additive, dominance, and imprinting effects for production and reproduction traits in Holstein cattle.

PubMed

Jiang, Jicai; Shen, Botong; O'Connell, Jeffrey R; VanRaden, Paul M; Cole, John B; Ma, Li

2017-05-30

Although genome-wide association and genomic selection studies have primarily focused on additive effects, dominance and imprinting effects play an important role in mammalian biology and development. The degree to which these non-additive genetic effects contribute to phenotypic variation and whether QTL acting in a non-additive manner can be detected in genetic association studies remain controversial. To empirically answer these questions, we analyzed a large cattle dataset that consisted of 42,701 genotyped Holstein cows with genotyped parents and phenotypic records for eight production and reproduction traits. SNP genotypes were phased in pedigree to determine the parent-of-origin of alleles, and a three-component GREML was applied to obtain variance decomposition for additive, dominance, and imprinting effects. The results showed a significant non-zero contribution from dominance to production traits but not to reproduction traits. Imprinting effects significantly contributed to both production and reproduction traits. Interestingly, imprinting effects contributed more to reproduction traits than to production traits. Using GWAS and imputation-based fine-mapping analyses, we identified and validated a dominance association signal with milk yield near RUNX2, a candidate gene that has been associated with milk production in mice. When adding non-additive effects into the prediction models, however, we observed little or no increase in prediction accuracy for the eight traits analyzed. Collectively, our results suggested that non-additive effects contributed a non-negligible amount (more for reproduction traits) to the total genetic variance of complex traits in cattle, and detection of QTLs with non-additive effect is possible in GWAS using a large dataset.

Classification of individual well-being scores for the determination of adverse health and productivity outcomes in employee populations.

PubMed

Shi, Yuyan; Sears, Lindsay E; Coberley, Carter R; Pope, James E

2013-04-01

Adverse health and productivity outcomes have imposed a considerable economic burden on employers. To facilitate optimal worksite intervention designs tailored to differing employee risk levels, the authors established cutoff points for an Individual Well-Being Score (IWBS) based on a global measure of well-being. Cross-sectional associations between IWBS and adverse health and productivity outcomes, including high health care cost, emergency room visits, short-term disability days, absenteeism, presenteeism, low job performance ratings, and low intentions to stay with the employer, were studied in a sample of 11,702 employees from a large employer. Receiver operating characteristics curves were evaluated to detect a single optimal cutoff value of IWBS for predicting 2 or more adverse outcomes. More granular segmentation was achieved by computing relative risks of each adverse outcome from logistic regressions accounting for sociodemographic characteristics. Results showed strong and significant nonlinear associations between IWBS and health and productivity outcomes. An IWBS of 75 was found to be the optimal single cutoff point to discriminate 2 or more adverse outcomes. Logistic regression models found abrupt reductions of relative risk also clustered at IWBS cutoffs of 53, 66, and 88, in addition to 75, which segmented employees into high, high-medium, medium, low-medium, and low risk groups. To determine validity and generalizability, cutoff values were applied in a smaller employee population (N=1853) and confirmed significant differences between risk groups across health and productivity outcomes. The reported segmentation of IWBS into discrete cohorts based on risk of adverse health and productivity outcomes should facilitate well-being comparisons and worksite interventions.

The effects of flue gas desulfurization (FGD) system additives on solid by-products. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huyck, K.A.; Tatum, G.S.; DeKraker, D.P.

This study was designed to examine characteristics of by-products from flue gas desulfurization (FGD) systems that use performance-enhancing additives. The by-products were evaluated for handling, disposal, properties, and utilization potential. This study was designed to identify potential operation-limiting consequences (fatal flaws) caused by using FGD system additives. It was not intended to be an all-encompassing study of the possible process, environmental, and utilization circumstances at each plant. Seven utilities conducting additive testing agreed to provide samples for this study both before and during their testing. Solid samples were collected from FGD systems using the following additives: di-basic acid (DBA), whichmore » is a mixture of succinic, glutaric, and adipic acids; formate; sulfur; ethylene diamine tetraacetic acid (EDTA); and chloride. Changes in handling properties that may alter process operations were observed at sites where DBS was used. Changes in leaching behavior, permeability and unconfined compressive strength (properties that affect by-product disposal properties) showed no clear trend for additive or system type. The intent of this study is to provide an overall assessment of potential system-limiting effects of FGD additive use. There were no overriding problems relating to disposal with the use of additives. However, properties of solids produced with and without additives should be tested at each site prior to use of an FGD system additive. This is necessary because of the variability in state disposal and permitting requirements and the influence of specific operating conditions on by-product properties.« less

Production scheduling with discrete and renewable additional resources

NASA Astrophysics Data System (ADS)

Kalinowski, K.; Grabowik, C.; Paprocka, I.; Kempa, W.

2015-11-01

In this paper an approach to planning of additional resources when scheduling operations are discussed. The considered resources are assumed to be discrete and renewable. In most research in scheduling domain, the basic and often the only type of regarded resources is a workstation. It can be understood as a machine, a device or even as a separated space on the shop floor. In many cases, during the detailed scheduling of operations the need of using more than one resource, required for its implementation, can be indicated. Resource requirements for an operation may relate to different resources or resources of the same type. Additional resources are most often referred to these human resources, tools or equipment, for which the limited availability in the manufacturing system may have an influence on the execution dates of some operations. In the paper the concept of the division into basic and additional resources and their planning method was shown. A situation in which sets of basic and additional resources are not separable - the same additional resource may be a basic resource for another operation is also considered. Scheduling of operations, including greater amount of resources can cause many difficulties, depending on whether the resource is involved in the entire time of operation, only in the selected part(s) of operation (e.g. as auxiliary staff at setup time) or cyclic - e.g. when an operator supports more than one machine, or supervises the execution of several operations. For this reason the dates and work times of resources participation in the operation can be different. Presented issues are crucial when modelling of production scheduling environment and designing of structures for the purpose of scheduling software development.

The use of NaCl addition for the improvement of polyhydroxyalkanoate production by Cupriavidus necator.

PubMed

Passanha, Pearl; Kedia, Gopal; Dinsdale, Richard M; Guwy, Alan J; Esteves, Sandra R

2014-07-01

External stress factors in the form of ionic species or temperature increases have been shown to produce a stress response leading to enhanced PHA production. The effect of five different NaCl concentrations, namely 3.5, 6.5, 9, 12 and 15 g/l NaCl on PHA productivity using Cupriavidus necator has been investigated alongside a control (no added NaCl). A dielectric spectroscopy probe was used to measure PHA accumulation online in conjunction with the chemical offline analysis of PHA. The highest PHA production was obtained with the addition of 9 g/l NaCl, which yielded 30% higher PHA than the control. Increasing the addition of NaCl to 15 g/l was found to inhibit the production of PHA. NaCl addition can therefore be used as a simple, low cost, sustainable, non toxic and non reactive external stress strategy for increasing PHA productivity. Copyright © 2014 Elsevier Ltd. All rights reserved.

Red mud addition in the raw meal for the production of Portland cement clinker.

PubMed

Tsakiridis, P E; Agatzini-Leonardou, S; Oustadakis, P

2004-12-10

The aim of the present research work was to investigate the possibility of adding red mud, an alkaline leaching waste, which is obtained from bauxite during the Bayer process for alumina production, in the raw meal for the production of Portland cement clinker. For that reason, two samples of raw meals were prepared: one with ordinary raw materials, as a reference sample ((PC)Ref), and another with 3.5% red mud ((PC)R/M). The effect on the reactivity of the raw mix was evaluated on the basis of the unreacted lime content in samples sintered at 1350, 1400 and 1450 degrees C. Subsequently, the clinkers were produced by sintering the two raw meals at 1450 degrees C. The results of chemical and mineralogical analyses as well as the microscopic examination showed that the use of the red mud did not affect the mineralogical characteristics of the so produced Portland cement clinker. Furthermore, both clinkers were tested by determining the grindability, setting time, compressive strength and expansibility. The hydration products were examined by XRD analysis at 2, 7, 28 and 90 days. The results of the physico-mechanical tests showed that the addition of the red mud did not negatively affect the quality of the produced cement.

Production of Low-Freezing-Point Highly Branched Alkanes through Michael Addition.

PubMed

Jing, Yaxuan; Xia, Qineng; Liu, Xiaohui; Wang, Yanqin

2017-12-22

A new approach for the production of low-freezing-point, high-quality fuels from lignocellulose-derived molecules was developed with Michael addition as the key step. Among the investigated catalysts, CoCl 2 ⋅6 H 2 O was found most active for the Michael addition of 2,4-pentanedione with FA (single aldol adduct of furfural and acetone, 4-(2-furanyl)-3-butene-2-one). Over CoCl 2 ⋅6 H 2 O, a high carbon yield of C 13 oxygenates (about 75 %) can be achieved under mild conditions (353 K, 20 h). After hydrodeoxygenation, low-freezing-point (<223 K) branched alkanes with 13 carbons within jet fuel ranges were obtained over a Pd/NbOPO 4 catalyst. Furthermore, C 18,23 fuel precursors could be easily synthesized through Michael addition of 2,4-pentanedione with DFA (double-condensation product of furfural and acetone) under mild conditions and the molar ratio of C 18 /C 23 is dependent on the reaction conditions of Michael addition. After hydrodeoxygenation, high density (0.8415 g mL -1 ) and low-freezing-point (<223 K) branched alkanes with 18, 23 carbons within lubricant range were also obtained over a Pd/NbOPO 4 catalyst. These highly branched alkanes can be directly used as transportation fuels or additives. This work opens a new strategy for the synthesis of highly branched alkanes with low freezing point from renewable biomass. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

[Effects of menthol as an additive in tobacco products and the need for regulation].

PubMed

Kahnert, S; Nair, U; Mons, U; Pötschke-Langer, M

2012-03-01

Menthol is the most widely used and the most prominent tobacco additive in tobacco products advertised and marketed by the tobacco industry. Besides its characteristic flavor, it possesses a variety of pharmacological properties facilitating tobacco smoke inhalation and potentiating dependence. These properties of menthol not only favor tobacco initiation and consumption but can also prevent smoking cessation. This article summarizes the effect of menthol as an additive in tobacco products and its effect on tobacco consumption that causes a number of chronic diseases and premature death and, therefore, counteracts tobacco control measures. Currently, there is no legislative regulation in Germany that considers the health hazard, addiction-enhancing and attractiveness-increasing properties of additives permitted in tobacco products. Effective regulation or even a ban could contribute to a reduction of tobacco consumption and, hence, save many people from a long-lasting tobacco dependence.

Inorganic carbon addition stimulates snow algae primary productivity

NASA Astrophysics Data System (ADS)

Hamilton, T. L.; Havig, J. R.

2017-12-01

Earth has experienced glacial/interglacial oscillations throughout its history. Today over 15 million square kilometers (5.8 million square miles) of Earth's land surface is covered in ice including glaciers, ice caps, and the ice sheets of Greenland and Antarctica, most of which are retreating as a consequence of increased atmospheric CO2. Glaciers are teeming with life and supraglacial snow and ice surfaces are often red due to blooms of photoautotrophic algae. Recent evidence suggests the red pigmentation, secondary carotenoids produced in part to thrive under high irradiation, lowers albedo and accelerates melt. However, there are relatively few studies that report the productivity of snow algae communities and the parameters that constrain their growth on snow and ice surfaces. Here, we demonstrate that snow algae primary productivity can be stimulated by the addition of inorganic carbon. We found an increase in light-dependent carbon assimilation in snow algae microcosms amended with increasing amounts of inorganic carbon. Our snow algae communities were dominated by typical cosmopolitan snow algae species recovered from Alpine and Arctic environments. The climate feedbacks necessary to enter and exit glacial/interglacial oscillations are poorly understood. Evidence and models agree that global Snowball events are accompanied by changes in atmospheric CO2 with increasing CO2 necessary for entering periods of interglacial time. Our results demonstrate a positive feedback between increased CO2 and snow algal productivity and presumably growth. With the recent call for bio-albedo effects to be considered in climate models, our results underscore the need for robust climate models to include feedbacks between supraglacial primary productivity, albedo, and atmospheric CO2.

Design for Health and Well Being: Knitted Products for Diabetics

NASA Astrophysics Data System (ADS)

Gault, A.

2016-07-01

This paper will discuss the design development, manufacturing and testing of knitted products maximizing the use of new innovations in Nano- technology and the integration of Phase Changing Materials specifically for diabetics. The project identified key aspects requiring design solutions to bring improvement to the circulatory problems with specific reference to the diabetic condition. Diabetics have particular difficulty in regulating their body temperature and this can result in the condition worsening, and resulting in loss of digits or limbs. The design of products to prevent the deterioration of the diabetic condition and to help those with limb loss was developed in collaboration with a Northern Ireland diabetic consultant, a product engineer and a knitwear designer. The fusion of ideas between the stakeholders resulted in the development and manufacture of a range of products that have been successfully tested at the yarn and fabric development stage and have been proven to maintain body temperature by either cooling or warming and therefore bring improvement to health and well-being. Whilst the product has a performance element the design ideas created desirable products that not only provided solutions to the brief but also resulted in products that had further market applications.

Application of flowmeter and depth-dependent water quality data for improved production well construction.

PubMed

Gossell, M A; Nishikawa, T; Hanson, R T; Izbicki, J A; Tabidian, M A; Bertine, K

1999-01-01

Ground water production wells commonly are designed to maximize well yield and, therefore, may be screened over several water-bearing zones. These water-bearing zones usually are identified, and their hydrogeologic characteristics and water quality are inferred, on the basis of indirect data such as geologic and geophysical logs. Production well designs based on these data may result in wells that are drilled deeper than necessary and are screened through zones having low permeability or poor-quality ground water. In this study, we examined the application of flowmeter logging and depth-dependent water quality samples for the improved design of production wells in a complex hydrogeologic setting. As a demonstration of these techniques, a flowmeter log and depth-dependent water quality data were collected from a long-screened production well within a multilayered coastal aquifer system in the Santa Clara-Calleguas Basin, Ventura County, California. Results showed that the well yields most of its water from four zones that constitute 58% of the screened interval. The importance of these zones to well yield was not readily discernible from indirect geologic or geophysical data. The flowmeter logs and downhole water quality data also show that small quantities of poor-quality water could degrade the overall quality of water from the well. The data obtained from one well can be applied to other proposed wells in the same hydrologic basin. The application of flowmeter and depth-dependent water quality data to well design can reduce installation costs and improve the quantity and quality of water produced from wells in complex multiple-aquifer systems.

Application of flowmeter and depth-dependent water quality data for improved production well construction

USGS Publications Warehouse

Gossell, M.A.; Nishikawa, Tracy; Hanson, Randall T.; Izbicki, John A.; Tabidian, M.A.; Bertine, K.

1999-01-01

Ground water production wells commonly are designed to maximize well yield and, therefore, may be screened over several water-bearing zones. These water-bearing zones usually are identified, and their hydrogeologic characteristics and water quality are inferred, on the basis of indirect data such as geologic and geophysical logs. Production well designs based on these data may result in wells that are drilled deeper than necessary and are screened through zones having low permeability or poor-quality ground water. In this study, we examined the application of flowmeter logging and depth-dependent water quality samples for the improved design of production wells in a complex hydrogeologic setting. As a demonstration of these techniques, a flowmeter log and depth-dependent water quality data were collected from a long-screened production well within a multilayered coastal aquifer system in the Santa Clara-Calleguas Basin, Ventura County, California. Results showed that the well yields most of its water from four zones that constitute 58% of the screened interval. The importance of these zones to well yield was not readily discernible from indirect geologic or geophysical data. The flowmeter logs and downhole water quality data also show that small quantities of poor-quality water could degrade the overall quality of water from the well. The data obtained from one well can be applied to other proposed wells in the same hydrologic basin. The application of flowmeter and depth-dependent water quality data to well design can reduce installation costs and improve the quantity and quality of water produced from wells in complex multiple-aquifer systems.

The importance of productive patient-professional interaction for the well-being of chronically ill patients.

PubMed

Cramm, Jane Murray; Nieboer, Anna Petra

2015-04-01

To investigate patient-professional interactions and identify the association between quality of care, productivity of patient-professional interaction, and chronically ill patients' well-being. Questionnaires were distributed to chronically ill patients [T1 (2011), 2,191/4,693 (47 %) respondents; T2 (2012), 1,722/4,350 (40 %) respondents]. Patients perceived a higher degree of productive interaction with general practitioners compared to other professionals. Bivariate analyses showed that patients' well-being at T2 was positively related to well-being at T1 (r = 0.70), quality of care (r = 0.12), and productive patient-professional interaction (r = 0.31; all p ≤ 0.001). Single status (r = -0.14), low education (r = -0.11), and female gender (r = -0.11; all p ≤ 0.001) were negatively associated with well-being. Multivariate analyses showed that after controlling for background characteristics and well-being at baseline quality of care is associated with patients' well-being at T2 (p ≤ 0.01). When productive patient-professional interactions were entered into the equation, they not only were related to patients' well-being (p ≤ 0.001) but also mediated the relationship between the quality of care and well-being. More productive patient-professional interactions were related to better well-being at T2 (B = 0.11), assuming that all other factors in the model remained constant. Productive patient-professional interactions are associated with chronically ill patients' well-being over time and mediate the relationship between well-being and quality of care. Improvement of the quality of chronic care delivery should always be accompanied by investment in the quality of relationships and communication between patients and professionals.

Classification of Individual Well-Being Scores for the Determination of Adverse Health and Productivity Outcomes in Employee Populations

PubMed Central

Sears, Lindsay E.; Coberley, Carter R.; Pope, James E.

2013-01-01

Abstract Adverse health and productivity outcomes have imposed a considerable economic burden on employers. To facilitate optimal worksite intervention designs tailored to differing employee risk levels, the authors established cutoff points for an Individual Well-Being Score (IWBS) based on a global measure of well-being. Cross-sectional associations between IWBS and adverse health and productivity outcomes, including high health care cost, emergency room visits, short-term disability days, absenteeism, presenteeism, low job performance ratings, and low intentions to stay with the employer, were studied in a sample of 11,702 employees from a large employer. Receiver operating characteristics curves were evaluated to detect a single optimal cutoff value of IWBS for predicting 2 or more adverse outcomes. More granular segmentation was achieved by computing relative risks of each adverse outcome from logistic regressions accounting for sociodemographic characteristics. Results showed strong and significant nonlinear associations between IWBS and health and productivity outcomes. An IWBS of 75 was found to be the optimal single cutoff point to discriminate 2 or more adverse outcomes. Logistic regression models found abrupt reductions of relative risk also clustered at IWBS cutoffs of 53, 66, and 88, in addition to 75, which segmented employees into high, high-medium, medium, low-medium, and low risk groups. To determine validity and generalizability, cutoff values were applied in a smaller employee population (N=1853) and confirmed significant differences between risk groups across health and productivity outcomes. The reported segmentation of IWBS into discrete cohorts based on risk of adverse health and productivity outcomes should facilitate well-being comparisons and worksite interventions. (Population Health Management 2013;16:90–98) PMID:23013034

CO2 Reduction Selective for C≥2 Products on Polycrystalline Copper with N-Substituted Pyridinium Additives.

PubMed

Han, Zhiji; Kortlever, Ruud; Chen, Hsiang-Yun; Peters, Jonas C; Agapie, Theodor

2017-08-23

Electrocatalytic CO 2 reduction to generate multicarbon products is of interest for applications in artificial photosynthetic schemes. This is a particularly attractive goal for CO 2 reduction by copper electrodes, where a broad range of hydrocarbon products can be generated but where selectivity for C-C coupled products relative to CH 4 and H 2 remains an impediment. Herein we report a simple yet highly selective catalytic system for CO 2 reduction to C ≥2 hydrocarbons on a polycrystalline Cu electrode in bicarbonate aqueous solution that uses N-substituted pyridinium additives. Selectivities of 70-80% for C 2 and C 3 products with a hydrocarbon ratio of C ≥2 /CH 4 significantly greater than 100 have been observed with several additives. 13 C-labeling studies verify CO 2 to be the sole carbon source in the C ≥2 hydrocarbons produced. Upon electroreduction, the N-substituted pyridinium additives lead to film deposition on the Cu electrode, identified in one case as the reductive coupling product of N -arylpyridinium. Product selectivity can also be tuned from C ≥2 species to H 2 (∼90%) while suppressing methane with certain N-heterocyclic additives.

Pipeline enhances Norman Wells potential

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Approval of an oil pipeline from halfway down Canada's MacKenzie River Valley at Norman Wells to N. Alberta has raised the potential for development of large reserves along with controversy over native claims. The project involves 2 closely related proposals. One, by Esso Resources, the exploration and production unit of Imperial Oil, will increase oil production from the Norman Wells field from 3000 bpd currently to 25,000 bpd. The other proposal, by Interprovincial Pipeline (N.W) Ltd., calls for construction of an underground pipeline to transport the additional production from Norman Wells to Alberta. The 560-mile, 12-in. pipeline will extend frommore » Norman Wells, which is 90 miles south of the Arctic Circle on the north shore of the Mackenzie River, south to the end of an existing line at Zama in N. Alberta. There will be 3 pumping stations en route. This work also discusses recovery, potential, drilling limitations, the processing plant, positive impact, and further development of the Norman Wells project.« less

Design of systems for productivity and well being.

PubMed

Edwards, Kasper; Jensen, Per Langaa

2014-01-01

It has always been an ambition within the ergonomic profession to ensure that design or redesign of production systems consider both productivity and employee well being, but there are many approaches to how to achieve this. This paper identifies the basic issues to be addressed in light of some research activities at DTU, especially by persons responsible for facilitating design processes. Four main issues must be addressed: (1) determining the limits and scope of the system to be designed; (2) identifying stakeholders related to the system and their role in the system design; (3) handling the process' different types of knowledge; and (4) emphasizing that performance management systems, key performance indicators (KPIs), and leadership are also part of the system design and must be given attention. With the examples presented, we argue that knowledge does exist to help system design facilitators address these basic issues. Copyright © 2013. Published by Elsevier Ltd.

30 CFR 250.195 - What notification does MMS require on the production status of wells?

Code of Federal Regulations, 2010 CFR

2010-07-01

... the well in a production status. You must confirm oral notification by telefax or e-mail within those... production status of wells? 250.195 Section 250.195 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT... Information and Reporting Requirements § 250.195 What notification does MMS require on the production status...

30 CFR 250.1629 - Additional production and fuel gas system requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

.... (4) Fire- and gas-detection system. (i) Fire (flame, heat, or smoke) sensors shall be installed in all enclosed classified areas. Gas sensors shall be installed in all inadequately ventilated, enclosed... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Additional production and fuel gas system...

30 CFR 250.1629 - Additional production and fuel gas system requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... structure. (4) Fire- and gas-detection system. (i) Fire (flame, heat, or smoke) sensors shall be installed in all enclosed classified areas. Gas sensors shall be installed in all inadequately ventilated... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Additional production and fuel gas system...

Variability of oil and gas well productivities for continuous (unconventional) petroleum accumulations

USGS Publications Warehouse

Charpentier, Ronald R.; Cook, Troy A.

2013-01-01

Over the last decade, oil and gas well productivities were estimated using decline-curve analysis for thousands of wells as part of U.S. Geological Survey (USGS) studies of continuous (unconventional) oil and gas resources in the United States. The estimated ultimate recoveries (EURs) of these wells show great variability that was analyzed at three scales: within an assessment unit (AU), among AUs of similar reservoir type, and among groups of AUs with different reservoir types. Within a particular oil or gas AU (such as the Barnett Shale), EURs vary by about two orders of magnitude between the most productive wells and the least productive ones (excluding those that are dry and abandoned). The distributions of EURs are highly skewed, with most of the wells in the lower part of the range. Continuous AUs were divided into four categories based on reservoir type and major commodity (oil or gas): coalbed gas, shale gas, other low-permeability gas AUs (such as tight sands), and low-permeability oil AUs. Within each of these categories, there is great variability from AU to AU, as shown by plots of multiple EUR distributions. Comparing the means of each distribution within a category shows that the means themselves have a skewed distribution, with a range of approximately one to two orders of magnitude. A comparison of the three gas categories (coalbed gas, shale gas, and other low-permeability gas AUs) shows large overlap in the ranges of EUR distributions. Generally, coalbed gas AUs have lower EUR distributions, shale gas AUs have intermediate sizes, and the other low-permeability gas AUs have higher EUR distributions. The plot of EUR distributions for each category shows the range of variation among developed AUs in an appropriate context for viewing the historical development within a particular AU. The Barnett Shale is used as an example to demonstrate that dividing wells into groups by time allows one to see the changes in EUR distribution. Subdivision into groups

Production optimization of sucker rod pumping wells producing viscous oil in Boscan field, Venezuela

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guirados, C.; Sandoval, J.; Rivas, O.

1995-12-31

Boscan field is located in the western coast of Maracaibo lake and is operated by Maraven S.A., affiliate of Petroleos de Venezuela S.A. It has 315 active wells, 252 of which are produced with sucker rod pumping. Other artificial lift methods currently applied in this field are hydraulic (piston) pumping (39 wells) and ESP (24 wells). This paper presents the results of the production optimization of two sucker rod pumping wells of Boscan field producing viscous oil. This optimization has been possible due to the development of a new production scheme and the application of system analysis in completion design.more » The new production scheme involves the utilization of a subsurface stuffing box assembly and a slotted housing, both designed and patented by Intevep S.A., affiliate of Petroleos de Venezuela S.A. The completion design method and software used in the optimization study were also developed by Intevep S.A. The new production scheme and design method proved to be effective in preventing the causes of the above mentioned problems, allowing the increase of oil production under better operating conditions.« less

21 CFR 1304.26 - Additional recordkeeping requirements applicable to drug products containing gamma-hydroxybutyric...

Code of Federal Regulations, 2010 CFR

2010-04-01

... to drug products containing gamma-hydroxybutyric acid. 1304.26 Section 1304.26 Food and Drugs DRUG....26 Additional recordkeeping requirements applicable to drug products containing gamma-hydroxybutyric....22, practitioners dispensing gamma-hydroxybutyric acid that is manufactured or distributed in...

Growth factor withdrawal in combination with sodium butyrate addition extends culture longevity and enhances antibody production in CHO cells.

PubMed

Hong, Jong Kwang; Lee, Gyun Min; Yoon, Sung Kwan

2011-09-10

The effect of growth factor (GF) and sodium butyrate (NaBu) on Chinese hamster ovary (CHO) cell growth, cell viability and antibody production was investigated using shaking flasks in GF-containing and GF-deficient medium containing 0, 1 and 3mM NaBu. The withdrawal of GF and the addition of NaBu suppressed cell growth, but they significantly increased specific antibody productivity, q(Ab). Interestingly, the withdrawal of GF in combination with the addition of NaBu markedly retarded cell death, leading to extended culture longevity. For instance, at 3mM NaBu, cell viability fell below 80% after day 4 in GF-containing medium, but it remained over 80% until day 18 in GF-deficient medium. Due to the enhanced q(Ab) and the extended culture longevity, approximately 2-fold increase in total antibody production was achieved in pseudo-perfusion culture with 1mM NaBu in GF-deficient medium, compared to the culture in GF-containing medium. The effect of GF and NaBu on the change in the expression and activity of cellular proteins, c-Myc, Bcl-2 and pyruvate dehydrogenase (PDH), was also investigated. Both the withdrawal of GF and the addition of NaBu decreased the expression of c-Myc. The expression of Bcl-2 was enhanced by the addition of NaBu in a dose-dependent manner while it was not affected by the withdrawal of GF. In addition, both the withdrawal of GF and the addition of NaBu reduced metabolic rates, q(Glc), q(Lac) and Y(Lac/Glc), and increased PDH activity while not affecting PDH expression, suggesting that they may reduce the glycolytic rates, but enhance the conversion rates of pyruvate to TCA intermediates. Taken together, the withdrawal of GF in combination with the addition of NaBu can be considered as a relevant strategy for alleviating NaBu-induced cell apoptosis and enhancing antibody production since it can be easily implemented as well as enhance q(Ab) and extend culture longevity. Copyright © 2011 Elsevier B.V. All rights reserved.

Regional long-term production modeling from a single well test, Mount Elbert Gas Hydrate Stratigraphic Test Well, Alaska North Slope

USGS Publications Warehouse

Anderson, B.J.; Kurihara, M.; White, M.D.; Moridis, G.J.; Wilson, S.J.; Pooladi-Darvish, M.; Gaddipati, M.; Masuda, Y.; Collett, T.S.; Hunter, R.B.; Narita, H.; Rose, K.; Boswell, R.

2011-01-01

Following the results from the open-hole formation pressure response test in the BPXA-DOE-USGS Mount Elbert Gas Hydrate Stratigraphic Test Well (Mount Elbert well) using Schlumberger's Modular Dynamics Formation Tester (MDT) wireline tool, the International Methane Hydrate Reservoir Simulator Code Comparison project performed long-term reservoir simulations on three different model reservoirs. These descriptions were based on 1) the Mount Elbert gas hydrate accumulation as delineated by an extensive history-matching exercise, 2) an estimation of the hydrate accumulation near the Prudhoe Bay L-pad, and 3) a reservoir that would be down-dip of the Prudhoe Bay L-pad and therefore warmer and deeper. All of these simulations were based, in part, on the results of the MDT results from the Mount Elbert Well. The comparison group's consensus value for the initial permeability of the hydrate-filled reservoir (k = 0.12 mD) and the permeability model based on the MDT history match were used as the basis for subsequent simulations on the three regional scenarios. The simulation results of the five different simulation codes, CMG STARS, HydrateResSim, MH-21 HYDRES, STOMP-HYD, and TOUGH+HYDRATE exhibit good qualitative agreement and the variability of potential methane production rates from gas hydrate reservoirs is illustrated. As expected, the predicted methane production rate increased with increasing in situ reservoir temperature; however, a significant delay in the onset of rapid hydrate dissociation is observed for a cold, homogeneous reservoir and it is found to be repeatable. The inclusion of reservoir heterogeneity in the description of this cold reservoir is shown to eliminate this delayed production. Overall, simulations utilized detailed information collected across the Mount Elbert reservoir either obtained or determined from geophysical well logs, including thickness (37 ft), porosity (35%), hydrate saturation (65%), intrinsic permeability (1000 mD), pore water

75 FR 33824 - Pharmaceutical Products and Chemical Intermediates, Fourth Review: Advice Concerning the Addition...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-15

... production of pharmaceuticals (pharmaceuticals zero-for-zero initiative) and to conduct periodic reviews to... eliminated duties on additional pharmaceutical items. The USTR indicated that participants in the zero- for-zero initiative are conducting a fourth review to determine if products can be added to the initiative...

Geothermal Energy Production from Oil/Gas Wells and Application for Building Cooling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Honggang; Liu, Xiaobing

One significant source of low-temperature geothermal energy is the coproduced hot water from oil/gas field production. In the United States, daily oil production has reached above 8 million barrels in recent years. Considering various conditions of wells, 5-10 times or more water can be coproduced in the range of temperature 120 F to 300 F. Like other geothermal resources, such energy source from oil/gas wells is under-utilized for its typical long distance from consumption sites. Many oil/gas fields, however, are relatively close (less than 10 miles) to consumers around cities. For instance, some petroleum fields in Pennsylvania are only amore » few miles away from the towns in Pittsburg area and some fields in Texas are quite close to Houston. In this paper, we evaluate geothermal potential from oil/gas wells by conducting numerical simulation and analysis of a fractured oil well in Hastings West field, Texas. The results suggest that hot water can be continuously coproduced from oil wells at a sufficient rate (about 4000 gallons/day from one well) for more than 100 years. Viable use of such geothermal source requires economical transportation of energy to consumers. The recently proposed two-step geothermal absorption (TSGA) system provides a promising energy transport technology that allows large-scale use of geothermal energy from thousands of oil/gas wells.« less

Drinking water treatment sludge as an effective additive for biogas production from food waste; kinetic evaluation and biomethane potential test.

PubMed

Ebrahimi-Nik, Mohammadali; Heidari, Ava; Ramezani Azghandi, Shamim; Asadi Mohammadi, Fatemeh; Younesi, Habibollah

2018-07-01

The effect of drinking water treatment sludge (DWTS) as a mixture additive, on biogas and methane production from food waste was studied. Mesophilic anaerobic digestion of food waste with 5 concentrations of DWTS (0, 2, 6, 12, and 18 ppm) was carried out. It was found that DWTS can significantly enhance biogas and methane yield. The highest biogas (671 Nml/g VS) as well as methane yield (522 Nml/g VS) was observed when 6 mg/kg DWTS was added. This is equal to 65 and 58 percent increase in comparison with the control digester. The calculated lag time for methane was found to be in between 3.3 and 4.7 days. The DWTS also reduced the lag phase and retention time. The biogas experimental data was fitted with the modified Gompertz and the first-order kinetic models with R 2 higher than 0.994 and 0.949, respectively. The ratio of the experimental biogas production to the theoretical biogas production (ɛ) for control sample was 0.53 while for other samples containing additive were higher than 0.78. Copyright © 2018 Elsevier Ltd. All rights reserved.

Regional long-term production modeling from a single well test, Mount Elbert Gas Hydrate Stratigraphic Test Well, Alaska North Slope

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, Brian J.; Kurihara, Masanori; White, Mark D.

2011-02-01

Following the results from the open-hole formation pressure response test in the BPXA-DOE-USGS Mount Elbert Gas Hydrate Stratigraphic Test Well (Mount Elbert well) using Schlumberger's Modular Dynamics Formation Tester (MDT) wireline tool, the International Methane Hydrate Reservoir Simulator Code Comparison project performed long-term reservoir simulations on three different model reservoirs. These descriptions were based on 1) the Mount Elbert gas hydrate accumulation as delineated by an extensive history-matching exercise, 2) an estimation of the hydrate accumulation near the Prudhoe Bay L-pad, and 3) a reservoir that would be down-dip of the Prudhoe Bay L-pad and therefore warmer and deeper. Allmore » of these simulations were based, in part, on the results of the MDT results from the Mount Elbert Well. The comparison group's consensus value for the initial permeability of the hydrate-filled reservoir (k = 0.12 mD) and the permeability model based on the MDT history match were used as the basis for subsequent simulations on the three regional scenarios. The simulation results of the five different simulation codes, CMG STARS, HydrateResSim, MH-21 HYDRES, STOMP-HYD, and TOUGH+HYDRATE exhibit good qualitative agreement and the variability of potential methane production rates from gas hydrate reservoirs is illustrated. As expected, the predicted methane production rate increased with increasing in situ reservoir temperature; however, a significant delay in the onset of rapid hydrate dissociation is observed for a cold, homogeneous reservoir and it is found to be repeatable. The inclusion of reservoir heterogeneity in the description of this cold reservoir is shown to eliminate this delayed production. Overall, simulations utilized detailed information collected across the Mount Elbert reservoir either obtained or determined from geophysical well logs, including thickness (37 ft), porosity (35%), hydrate saturation (65%), intrinsic permeability (1000 mD), pore

CO 2 Reduction Selective for C ≥2 Products on Polycrystalline Copper with N-Substituted Pyridinium Additives

DOE PAGES

Han, Zhiji; Kortlever, Ruud; Chen, Hsiang -Yun; ...

2017-07-21

Electrocatalytic CO 2 reduction to generate multicarbon products is of interest for applications in artificial photosynthetic schemes. This is a particularly attractive goal for CO 2 reduction by copper electrodes, where a broad range of hydrocarbon products can be generated but where selectivity for C–C coupled products relative to CH 4 and H 2 remains an impediment. Herein we report a simple yet highly selective catalytic system for CO 2 reduction to C ≥2 hydrocarbons on a polycrystalline Cu electrode in bicarbonate aqueous solution that uses N-substituted pyridinium additives. Selectivities of 70–80% for C 2 and C 3 products withmore » a hydrocarbon ratio of C ≥2/CH 4 significantly greater than 100 have been observed with several additives. 13C-labeling studies verify CO 2 to be the sole carbon source in the C ≥2 hydrocarbons produced. Upon electroreduction, the N-substituted pyridinium additives lead to film deposition on the Cu electrode, identified in one case as the reductive coupling product of N-arylpyridinium. As a result, product selectivity can also be tuned from C ≥2 species to H 2 (~90%) while suppressing methane with certain N-heterocyclic additives.« less

CO 2 Reduction Selective for C ≥2 Products on Polycrystalline Copper with N-Substituted Pyridinium Additives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Han, Zhiji; Kortlever, Ruud; Chen, Hsiang -Yun

Electrocatalytic CO 2 reduction to generate multicarbon products is of interest for applications in artificial photosynthetic schemes. This is a particularly attractive goal for CO 2 reduction by copper electrodes, where a broad range of hydrocarbon products can be generated but where selectivity for C–C coupled products relative to CH 4 and H 2 remains an impediment. Herein we report a simple yet highly selective catalytic system for CO 2 reduction to C ≥2 hydrocarbons on a polycrystalline Cu electrode in bicarbonate aqueous solution that uses N-substituted pyridinium additives. Selectivities of 70–80% for C 2 and C 3 products withmore » a hydrocarbon ratio of C ≥2/CH 4 significantly greater than 100 have been observed with several additives. 13C-labeling studies verify CO 2 to be the sole carbon source in the C ≥2 hydrocarbons produced. Upon electroreduction, the N-substituted pyridinium additives lead to film deposition on the Cu electrode, identified in one case as the reductive coupling product of N-arylpyridinium. As a result, product selectivity can also be tuned from C ≥2 species to H 2 (~90%) while suppressing methane with certain N-heterocyclic additives.« less

Dropwise additive manufacturing of pharmaceutical products for melt-based dosage forms.

PubMed

Içten, Elçin; Giridhar, Arun; Taylor, Lynne S; Nagy, Zoltan K; Reklaitis, Gintaras V

2015-05-01

The US Food and Drug Administration introduced the quality by design approach and process analytical technology guidance to encourage innovation and efficiency in pharmaceutical development, manufacturing, and quality assurance. As part of this renewed emphasis on the improvement of manufacturing, the pharmaceutical industry has begun to develop more efficient production processes with more intensive use of online measurement and sensing, real-time quality control, and process control tools. Here, we present dropwise additive manufacturing of pharmaceutical products (DAMPP) as an alternative to conventional pharmaceutical manufacturing methods. This mini-manufacturing process for the production of pharmaceuticals utilizes drop on demand printing technology for automated and controlled deposition of melt-based formulations onto edible substrates. The advantages of drop-on-demand technology, including reproducible production of small droplets, adjustable drop sizing, high placement accuracy, and flexible use of different formulations, enable production of individualized dosing even for low-dose and high-potency drugs. In this work, DAMPP is used to produce solid oral dosage forms from hot melts of an active pharmaceutical ingredient and a polymer. The dosage forms are analyzed to show the reproducibility of dosing and the dissolution behavior of different formulations. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association.

Indications of Transformation Products from Hydraulic Fracturing Additives in Shale-Gas Wastewater.

PubMed

Hoelzer, Kathrin; Sumner, Andrew J; Karatum, Osman; Nelson, Robert K; Drollette, Brian D; O'Connor, Megan P; D'Ambro, Emma L; Getzinger, Gordon J; Ferguson, P Lee; Reddy, Christopher M; Elsner, Martin; Plata, Desiree L

2016-08-02

Unconventional natural gas development (UNGD) generates large volumes of wastewater, the detailed composition of which must be known for adequate risk assessment and treatment. In particular, transformation products of geogenic compounds and disclosed additives have not been described. This study investigated six Fayetteville Shale wastewater samples for organic composition using a suite of one- and two-dimensional gas chromatographic techniques to capture a broad distribution of chemical structures. Following the application of strict compound-identification-confidence criteria, we classified compounds according to their putative origin. Samples displayed distinct chemical distributions composed of typical geogenic substances (hydrocarbons and hopane biomarkers), disclosed UNGD additives (e.g., hydrocarbons, phthalates such as diisobutyl phthalate, and radical initiators such as azobis(isobutyronitrile)), and undisclosed compounds (e.g., halogenated hydrocarbons, such as 2-bromohexane or 4-bromoheptane). Undisclosed chloromethyl alkanoates (chloromethyl propanoate, pentanoate, and octanoate) were identified as potential delayed acids (i.e., those that release acidic moieties only after hydrolytic cleavage, the rate of which could be potentially controlled), suggesting they were deliberately introduced to react in the subsurface. In contrast, the identification of halogenated methanes and acetones suggested that those compounds were formed as unintended byproducts. Our study highlights the possibility that UNGD operations generate transformation products and underscores the value of disclosing additives injected into the subsurface.

Improvement of bioinsecticides production through adaptation of Bacillus thuringiensis cells to heat treatment and NaCl addition.

PubMed

Ghribi, D; Zouari, N; Jaoua, S

2005-01-01

The present work aimed to increase yields of delta-endotoxin production through adaptation of Bacillus thuringiensis cells to heat shock and sodium chloride and to investigate their involvements in bioinsecticides production improvement. Growing B. thuringiensis cells were heat treated after different incubation times to study the response of the adaptative surviving cells in terms of delta-endotoxin synthesis. Similarly, adaptation of B. thuringiensis cells to sodium chloride was investigated. Adaptation to combined stressors was also evaluated. When applied separately in the glucose-based medium, 20-min heat treatment of 6-h-old cultures and addition of 7 g l(-1) NaCl at the beginning of the incubation gave respectively 38 and 27% delta-endotoxin production improvements. Heat shock improved toxin synthesis yields, while NaCl addition improved delta-endotoxin production by increasing the spore titres without significant effect on toxin synthesis yields. Cumulative improvements (66%) were obtained by combination of the two stressors at the conditions previously established for each one. Interestingly, when the similar approach was conducted by using the large scale production medium based on gruel and fish meal, 17, 8 and 29% delta-endotoxin production improvements were respectively, obtained with heat shock, NaCl and combined stressors. Heat treatment of vegetative B. thuringiensis cells and NaCl addition to the culture media improved bioinsecticides production. Heat treatment increased toxin synthesis yields, while addition of NaCl increased biomass production yields. Cumulative improvements of 66 and 29% were obtained in glucose and economic production media, respectively. Overproduction of bioinsecticides by B. thuringiensis could be obtained by the combination of heat treatment of vegetative cells and addition of NaCl to the culture medium. This should contribute to a significant reduction of the cost of B. thuringiensis bioinsecticides production and

The effects of leachate recirculation with supplemental water addition on methane production and waste decomposition in a simulated tropical landfill.

PubMed

Sanphoti, N; Towprayoon, S; Chaiprasert, P; Nopharatana, A

2006-10-01

In order to increase methane production efficiency, leachate recirculation is applied in landfills to increase moisture content and circulate organic matter back into the landfill cell. In the case of tropical landfills, where high temperature and evaporation occurs, leachate recirculation may not be enough to maintain the moisture content, therefore supplemental water addition into the cell is an option that could help stabilize moisture levels as well as stimulate biological activity. The objectives of this study were to determine the effects of leachate recirculation and supplemental water addition on municipal solid waste decomposition and methane production in three anaerobic digestion reactors. Anaerobic digestion with leachate recirculation and supplemental water addition showed the highest performance in terms of cumulative methane production and the stabilization period time required. It produced an accumulated methane production of 54.87 l/kg dry weight of MSW at an average rate of 0.58 l/kg dry weight/d and reached the stabilization phase on day 180. The leachate recirculation reactor provided 17.04 l/kg dry weight at a rate of 0.14l/kg dry weight/d and reached the stabilization phase on day 290. The control reactor provided 9.02 l/kg dry weight at a rate of 0.10 l/kg dry weight/d, and reached the stabilization phase on day 270. Increasing the organic loading rate (OLR) after the waste had reached the stabilization phase made it possible to increase the methane content of the gas, the methane production rate, and the COD removal. Comparison of the reactors' efficiencies at maximum OLR (5 kgCOD/m(3)/d) in terms of the methane production rate showed that the reactor using leachate recirculation with supplemental water addition still gave the highest performance (1.56 l/kg dry weight/d), whereas the leachate recirculation reactor and the control reactor provided 0.69 l/kg dry weight/d and 0.43 l/kg dry weight/d, respectively. However, when considering

Comparison of the Utility of Two Assessments for Explaining and Predicting Productivity Change: Well-Being Versus an HRA.

PubMed

Gandy, William M; Coberley, Carter; Pope, James E; Rula, Elizabeth Y

2016-01-01

To compare utility of employee well-being to health risk assessment (HRA) as predictors of productivity change. Panel data from 2189 employees who completed surveys 2 years apart were used in hierarchical models comparing the influence of well-being and health risk on longitudinal changes in presenteeism and job performance. Absenteeism change was evaluated in a nonexempt subsample. Change in well-being was the most significant independent predictor of productivity change across all three measures. Comparing hierarchical models, well-being models performed significantly better than HRA models. The HRA added no incremental explanatory power over well-being in combined models. Alone, nonphysical health well-being components outperformed the HRA for all productivity measures. Well-being offers a more comprehensive measure of factors that influence productivity and can be considered preferential to HRA in understanding and addressing suboptimal productivity.

Dual permeability flow behavior for modeling horizontal well production in fractured-vuggy carbonate reservoirs

NASA Astrophysics Data System (ADS)

Guo, Jian-Chun; Nie, Ren-Shi; Jia, Yong-Lu

2012-09-01

SummaryFractured-vuggy carbonate reservoirs are composed of by matrix, fracture, and vug systems. This paper is the first investigation into the dual permeability flow issue for horizontal well production in a fractured-vuggy carbonate reservoir. Considering dispersed vugs in carbonate reservoirs and treating media directly connected with horizontal wellbore as the matrix and fracture systems, a test analysis model of a horizontal well was created, and triple porosity and dual permeability flow behavior were modeled. Standard log-log type curves were drawn up by numerical simulation and flow behavior characteristics were thoroughly analyzed. Numerical simulations showed that type curves are dominated by external boundary conditions as well as the permeability ratio of the fracture system to the sum of fracture and matrix systems. The parameter κ is only relevant to the dual permeability model, and if κ is one, then the dual permeability model is equivalent to the single permeability model. There are seven main flow regimes with constant rate of horizontal well production and five flow regimes with constant wellbore pressure of horizontal well production; different flow regimes have different flow behavior characteristics. Early radial flow and linear flow regimes are typical characteristics of horizontal well production; duration of early radial flow regime is usually short because formation thickness is generally less than 100 m. Derivative curves are W-shaped, which is a reflection of inter-porosity flows between matrix, fracture, and vug systems. A distorted W-shape, which could be produced in certain situations, such as one involving an erroneously low time of inter-porosity flows, would handicap the recognition of a linear flow regime. A real case application was successfully implemented, and some useful reservoir parameters (e.g., permeability and inter-porosity flow factor) were obtained from well testing interpretation.

Design and additive manufacture for flow chemistry.

PubMed

Capel, Andrew J; Edmondson, Steve; Christie, Steven D R; Goodridge, Ruth D; Bibb, Richard J; Thurstans, Matthew

2013-12-07

We review the use of additive manufacturing (AM) as a novel manufacturing technique for the production of milli-scale reactor systems. Five well-developed additive manufacturing techniques: stereolithography (SL), multi-jet modelling (MJM), selective laser melting (SLM), laser sintering (LS) and fused deposition modelling (FDM) were used to manufacture a number of miniaturised reactors which were tested using a range of organic and inorganic reactions.

Dosage and duration effects of nitrogen additions on ectomycorrhizal sporocarp production and functioning: an example from two N-limited boreal forests.

PubMed

Hasselquist, Niles J; Högberg, Peter

2014-08-01

Although it is well known that nitrogen (N) additions strongly affect ectomycorrhizal (EM) fungal community composition, less is known about how different N application rates and duration of N additions affect the functional role EM fungi play in the forest N cycle.We measured EM sporocarp abundance and species richness as well as determined the δ (15)N in EM sporocarps and tree foliage in two Pinus sylvestris forests characterized by short- and long-term N addition histories and multiple N addition treatments. After 20 and 39 years of N additions, two of the long-term N addition treatments were terminated, thereby providing a unique opportunity to examine the temporal recovery of EM sporocarps after cessation of high N loading.In general, increasing N availability significantly reduced EM sporocarp production, species richness, and the amount of N retained in EM sporocarps. However, these general responses were strongly dependent on the application rate and duration of N additions. The annual addition of 20 kg·N·ha(-1) for the past 6 years resulted in a slight increase in the production and retention of N in EM sporocarps, whereas the addition of 100 kg·N·ha(-1)·yr(-1) during the same period nearly eliminated EM sporocarps. In contrast, long-term additions of N at rates of ca. 35 or 70 kg·N·ha(-1)·yr(-1) for the past 40 years did not eliminate tree carbon allocation to EM sporocarps, although there was a decrease in the abundance and a shift in the dominant EM sporocarp taxa. Despite no immediate recovery, EM sporocarp abundance and species richness approached those of the control 20 years after terminating N additions in the most heavily fertilized treatment, suggesting a recovery of carbon allocation to EM sporocarps after cessation of high N loading.Our results provide evidence for a tight coupling between tree carbon allocation to and N retention in EM sporocarps and moreover highlight the potential use of δ (15)N in EM sporocarps as a

Effect of biochar addition on hydrogen and methane production in two-phase anaerobic digestion of aqueous carbohydrates food waste.

PubMed

Sunyoto, Nimas M S; Zhu, Mingming; Zhang, Zhezi; Zhang, Dongke

2016-11-01

Effect of biochar addition on hydrogen and methane production in two-phase anaerobic digestion of aqueous carbohydrates was studied using bench-scale bioreactors. The cultures with biochar additions were placed in 100ml reactors and incubated at 35°C and pH 5 for hydrogen production. The residual cultures were then used for methane production, incubated at 35°C and pH 7. Daily yields of hydrogen and methane and weekly yield of volatile fatty acids (VFA) were measured. The hydrogen and methane production potentials, rate and lag phases of the two phases were analysed using the Gompertz model. The results showed that biochar addition increased the maximum production rates of hydrogen by 32.5% and methane 41.6%, improved hydrogen yield by 31.0% and methane 10.0%, and shortened the lag phases in the two phases by 36.0% and 41.0%, respectively. Biochar addition also enhanced VFA generation during hydrogen production and VFA degradation in methane production. Copyright © 2016 Elsevier Ltd. All rights reserved.

Simulation of Ground-Water Flow and Areas Contributing Recharge to Production Wells in Contrasting Glacial Valley-Fill Settings, Rhode Island

USGS Publications Warehouse

Friesz, Paul J.; Stone, Janet Radway

2007-01-01

Areas contributing recharge and sources of water to a production well field in the Village of Harrisville and to a production well field in the Town of Richmond were delineated on the basis of calibrated, steady-state ground-water-flow models representing average hydrologic conditions. The study sites represent contrasting glacial valley-fill settings. The area contributing recharge to a well is defined as the surface area where water recharges the ground water and then flows toward and discharges to the well. In Harrisville, the production well field is composed of three wells in a narrow, approximately 0.5-mile-wide, valley-fill setting on opposite sides of Batty Brook, a small intermittent stream that drains 0.64 square mile at its confluence with the Clear River. Glacial stratified deposits are generally less areally extensive than previously published. The production wells are screened in a thin (30 feet) but transmissive aquifer. Paired measurements of ground-water and surface-water levels indicated that the direction of flow between the brook and the aquifer was generally downward during pumping conditions. Long-term mean annual streamflow from two streams upgradient of the well field totaled 0.72 cubic feet per second. The simulated area contributing recharge for the 2005 average well-field withdrawal rate of 224 gallons per minute extended upgradient to ground-water divides in upland areas and encompassed 0.17 square mile. The well field derived 62 percent of pumped water from intercepted ground water and 38 percent from infiltrated stream water from the Batty Brook watershed. For the maximum simulated well-field withdrawal of 600 gallons per minute, the area contributing recharge expanded to 0.44 square mile to intercept additional ground water and infiltration of stream water; the percentage of water derived from surface water, however, was the same as for the average pumping rate. Because of the small size of Batty Brook watershed, most of the

Improving aerobic stability and biogas production of maize silage using silage additives.

PubMed

Herrmann, Christiane; Idler, Christine; Heiermann, Monika

2015-12-01

The effects of air stress during storage, exposure to air at feed-out, and treatment with silage additives to enhance aerobic stability on methane production from maize silage were investigated at laboratory scale. Up to 17% of the methane potential of maize without additive was lost during seven days exposure to air on feed-out. Air stress during storage reduced aerobic stability and further increased methane losses. A chemical additive containing salts of benzoate and propionate, and inoculants containing heterofermentative lactic acid bacteria were effective to increase aerobic stability and resulted in up to 29% higher methane yields after exposure to air. Exclusion of air to the best possible extent and high aerobic stabilities should be primary objectives when ensiling biogas feedstocks. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

Data regarding hydraulic fracturing distributions and treatment fluids, additives, proppants, and water volumes applied to wells drilled in the United States from 1947 through 2010

USGS Publications Warehouse

Gallegos, Tanya J.; Varela, Brian A.

2015-01-01

Comprehensive, published, and publicly available data regarding the extent, location, and character of hydraulic fracturing in the United States are scarce. The objective of this data series is to publish data related to hydraulic fracturing in the public domain. The spreadsheets released with this data series contain derivative datasets aggregated temporally and spatially from the commercial and proprietary IHS database of U.S. oil and gas production and well data (IHS Energy, 2011). These datasets, served in 21 spreadsheets in Microsoft Excel (.xlsx) format, outline the geographical distributions of hydraulic fracturing treatments and associated wells (including well drill-hole directions) as well as water volumes, proppants, treatment fluids, and additives used in hydraulic fracturing treatments in the United States from 1947 through 2010. This report also describes the data—extraction/aggregation processing steps, field names and descriptions, field types and sources. An associated scientific investigation report (Gallegos and Varela, 2014) provides a detailed analysis of the data presented in this data series and comparisons of the data and trends to the literature.

The association between modifiable well-being risks and productivity: a longitudinal study in pooled employer sample.

PubMed

Shi, Yuyan; Sears, Lindsay E; Coberley, Carter R; Pope, James E

2013-04-01

To examine the longitudinal relationship between modifiable well-being risks and productivity. A total of 19,121 employees from five employers participated in baseline and follow-up well-being assessment surveys. Multivariate regressions assessed whether changes in absenteeism, presenteeism, and job performance were associated with changes in 19 modifiable well-being risks. Over time, a 5% reduction in total count of well-being risks was significantly associated with 0.74% decrease in absenteeism, 2.38% decrease in presenteeism, and 0.24% increase in performance. High blood pressure, recurring pain, unhealthy diet, inadequate exercise, poor emotional health, poor supervisor relationship, not utilizing strengths doing job, and organization unsupportive of well-being had greater independent contributions in explaining productivity impairment. The often-ignored well-being risks such as work-related and financial health risks provided incremental explanation of longitudinal productivity variations beyond traditional measures of health-related risks.

Herbicides and their transformation products in source-water aquifers tapped by public-supply wells in Illinois, 2001-02

USGS Publications Warehouse

Mills, Patrick C.; McMillan, William D.

2004-01-01

to a recharge area and (or) the stronger the hydraulic connection between an aquifer and a recharge area, the younger the ground water and the more vulnerable the aquifer will be to contamination by herbicide compounds. The weak relation between current (2001) statewide application rates of herbicides and current (2001-02) occurrence of herbicide compounds in source-water aquifers indicates that additional factors must be considered when relating herbicide-application rates to occurrence. These factors include historical application rates and the mobility and persistence of the various herbicide compounds in ground-water systems. Frequency of detection and concentrations of herbicides compounds in the State?s source-water aquifers are indicated to be highest during the spring, when crops are planted and herbicides primarily are applied. Excess nitrate (concentrations of nitrate, as nitrogen, higher than 3 milligrams per liter) in ground water strongly indicates the co-occurrence of herbicide compounds. However, nitrate concentrations are not a reliable indicator of herbicide-compound concentrations. The inverse relation found between current use of land for corn and soybean production and current occurrence of herbicide compounds in underlying aquifers indicates that various factors, along with current agricultural land use, contribute to herbicide occurrence. These factors include, among others, land-use history, ground-water age, ground-water-flow patterns, geology, soil microbiology, and chemistry and persistence of the herbicide compounds. Detection of agriculture-specific herbicide compounds in 71 percent of samples from urban areas with no current or recent agricultural land use near the sampled wells indicates that recharge to certain high-capacity supply wells may originate at considerable distances (up to about 10 miles) from the wells. Essentially no difference was found between the analytical results for herbicides in paired unfiltered and filtered samples,

Seagrass metabolism across a productivity gradient using the eddy covariance, Eulerian control volume, and biomass addition techniques

NASA Astrophysics Data System (ADS)

Long, Matthew H.; Berg, Peter; Falter, James L.

2015-05-01

The net ecosystem metabolism of the seagrass Thalassia testudinum was studied across a nutrient and productivity gradient in Florida Bay, Florida, using the Eulerian control volume, eddy covariance, and biomass addition techniques. In situ oxygen fluxes were determined by a triangular Eulerian control volume with sides 250 m long and by eddy covariance instrumentation at its center. The biomass addition technique evaluated the aboveground seagrass productivity through the net biomass added. The spatial and temporal resolutions, accuracies, and applicability of each method were compared. The eddy covariance technique better resolved the short-term flux rates and the productivity gradient across the bay, which was consistent with the long-term measurements from the biomass addition technique. The net primary production rates from the biomass addition technique, which were expected to show greater autotrophy due to the exclusion of sediment metabolism and belowground production, were 71, 53, and 30 mmol carbon m-2 d-1 at 3 sites across the bay. The net ecosystem metabolism was 35, 25, and 11 mmol oxygen m-2 d-1 from the eddy covariance technique and 10, -103, and 14 mmol oxygen m-2 d-1 from the Eulerian control volume across the same sites, respectively. The low-flow conditions in the shallow bays allowed for periodic stratification and long residence times within the Eulerian control volume that likely reduced its precision. Overall, the eddy covariance technique had the highest temporal resolution while producing accurate long-term flux rates that surpassed the capabilities of the biomass addition and Eulerian control volume techniques in these shallow coastal bays.

Indications of Transformation Products from Hydraulic Fracturing Additives in Shale Gas Wastewater

NASA Astrophysics Data System (ADS)

Elsner, Martin; Hoelzer, Kathrin; Sumner, Andrew J.; Karatum, Osman; Nelson, Robert K.; Drollette, Brian D.; O'Connor, Megan P.; D'Ambro, Emma; Getzinger, Gordon J.; Ferguson, P. Lee; Reddy, Christopher M.; Plata, Desiree L.

2016-04-01

Unconventional natural gas development (UNGD) generates large volumes of wastewater, whose detailed composition must be known for adequate risk assessment and treatment. In particular, there is a need to elucidate the structures of organic chemical additives, extracted geogenic compounds, and transformation products. This study investigated six Fayetteville Shale UNGD wastewater samples for their organic composition using purge-and-trap gas chromatography-mass spectrometry (P&T-GC-MS) in combination with liquid-liquid extraction with comprehensive two-dimensional gas chromatography-time of flight-mass spectrometry (GCxGC-TOF-MS). Following application of strict compound identification confidence criteria, we classified compounds according to their putative origin. Samples displayed distinct chemical distributions composed of typical geogenic substances (hydrocarbons), disclosed UNGD additives (e.g., hydrocarbons, phthalates, such as diisobutyl phthalate, and radical initiators, such as azobisisobutyronitrile), and undisclosed compounds (e.g., halogenated hydrocarbons, such as 2-bromohexane or 4-bromoheptane). Undisclosed chloromethyl alkanoates (chloromethyl propanoate, pentanoate, and octanoate) were identified as putative delayed acids (those that release acidic moieties only after hydrolytic cleavage, whose rate could potentially be controlled), suggesting they were deliberately introduced to react in the subsurface. Identification of halogenated methanes and acetones, in contrast, suggested they were formed as unintended by-products. Our study highlights the possibility that UNGD operations generate transformation products, knowledge of which is crucial for risk assessment and treatment strategies, and underscores the value of disclosing potential precursors that are injected into the subsurface.

Prediction of the future number of wells in production (in Spanish)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coca, B.P.

1981-01-01

A method to predict the number of wells that will continue producing at a certain date in the future is presented. The method is applicable to reservoirs of the depletion type and is based on the survival probability concept. This is useful when forecasting by empirical methods. An example of a field in primary production is presented.

Dropwise additive manufacturing of pharmaceutical products for amorphous and self emulsifying drug delivery systems.

PubMed

Içten, Elçin; Purohit, Hitesh S; Wallace, Chelsey; Giridhar, Arun; Taylor, Lynne S; Nagy, Zoltan K; Reklaitis, Gintaras V

2017-05-30

The improvements in healthcare systems and the advent of the precision medicine initiative have created the need to develop more innovative manufacturing methods for the delivery and production of individualized dosing and personalized treatments. In accordance with the changes observed in healthcare systems towards more innovative therapies, this paper presents dropwise additive manufacturing of pharmaceutical products (DAMPP) for small scale, distributed manufacturing of individualized dosing as an alternative to conventional manufacturing methods A dropwise additive manufacturing process for amorphous and self-emulsifying drug delivery systems is reported, which utilizes drop-on-demand printing technology for automated and controlled deposition of melt-based formulations onto inert tablets. The advantages of drop on demand technology include reproducible production of droplets with adjustable sizing and high placement accuracy, which enable production of individualized dosing even for low dose and high potency drugs. Flexible use of different formulations, such as lipid-based formulations, allows enhancement of the solubility of poorly water soluble and highly lipophilic drugs with DAMPP. Here, DAMPP is used to produce solid oral dosage forms from melts of an active pharmaceutical ingredient and a surfactant. The dosage forms are analyzed to show the amorphous nature, self-emulsifying drug delivery system characteristics and dissolution behavior of these formulations. Copyright © 2017 Elsevier B.V. All rights reserved.

SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scott Reeves

2003-03-01

Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Type curve matching continued during the reporting period. (2) A second data collection trip to Tulsa was performed to gather information on the additional reservoirs to be included in the analysis. Created updated

A preliminary evaluation of vertical separation between production intervals of coalbed-methane wells and water-supply wells in the Raton basin, Huerfano and Las Animas Counties, Colorado, 1999-2004

USGS Publications Warehouse

Watts, Kenneth R.

2006-01-01

The Raton Basin in southern Colorado and northern New Mexico is undergoing increased development of its coalbed-methane resources. Annual production of methane from coalbeds in the Raton Basin in Huerfano and Las Animas Counties, Colorado, increased from about 28,000,000 thousand cubic feet from 478 wells to about 80,000,000 thousand cubic feet from 1,543 wells, during 1999-2004. Annual ground-water withdrawals for coalbed-methane production increased from about 1.45 billion gallons from 480 wells to about 3.64 billion gallons from 1,568 wells, during 1999-2004. Where the coalbeds are deeply buried near the center of the Raton Basin, water pressure may be reduced as much as 250 to 300 pounds per square inch to produce the methane from the coalbeds, which is equivalent to a 577- to 692-foot lowering of water level. In 2001, the U.S. Geological Survey, in cooperation with the Colorado Water Conservation Board, began an evaluation of the potential effects of coalbed- methane production on the availability and sustainability of ground-water resources. In 2003, there were an estimated 1,370 water-supply wells in the Raton Basin in Colorado, and about 90 percent of these water-supply wells were less than 450 feet deep. The tops of the production (perforated) interval of 90 percent of the coalbed-methane wells in the Raton Basin (for which data were available) are deeper than about 675 feet. The potential for interference of coalbed-methane wells with nearby water-supply wells likely is limited because in most areas their respective production intervals are separated by more than a hundred to a few thousand feet of rock. The estimated vertical separation between production intervals of coalbed-methane and water-supply wells is less than 100 feet in an area about 1 to 6 miles west and southwest of Trinidad Lake and a few other isolated areas. It is assumed that in areas with less than 100 feet of vertical separation, production by coalbed-methane wells has a greater

Natural antimicrobial/antioxidant agents in meat and poultry products as well as fruits and vegetables: A review.

PubMed

Aziz, Marya; Karboune, Salwa

2018-02-11

Synthetic preservatives are widely used by the food industry to control the growth of spoilage and pathogenic microorganisms and to inhibit the process of lipid oxidation extending the shelf-life, quality and safety of food products. However, consumer's preference for natural food additives and concern regarding the safety of synthetic preservatives prompted the food industry to look for natural alternatives. Natural antimicrobials, including plant extracts and their essential oils, enzymes, peptides, bacteriocins, bacteriophages, and fermented ingredients have all been shown to have the potential for use as alternatives to chemical antimicrobials. Some spices, herbs and other plant extracts were also reported to be strong antioxidants. The antimicrobial/antioxidant activities of some plant extracts and/or their essential oils are mainly due to the presence of some major bioactive compounds, including phenolic acids, terpenes, aldehydes, and flavonoids. The proposed mechanisms of action of these natural preservatives are reported. An overview of the research done on the direct incorporation of natural preservatives agents into meat and poultry products as well as fruit and vegetables to extend their shelf-life is presented. The development of edible packaging materials containing natural preservatives is growing and their applications in selected food products are also presented in this review.

Comparison of drilling reports and detailed geophysical analysis of ground-water production in bedrock wells

USGS Publications Warehouse

Paillet, Frederick; Duncanson, Russell

1994-01-01

The most extensive data base for fractured bedrock aquifers consists of drilling reports maintained by various state agencies. We investigated the accuracy and reliability of such reports by comparing a representative set of reports for nine wells drilled by conventional air percussion methods in granite with a suite of geophysical logs for the same wells designed to identify the depths of fractures intersecting the well bore which may have produced water during aquifer tests. Production estimates reported by the driller ranged from less than 1 to almost 10 gallons per minute. The moderate drawdowns maintained during subsequent production tests were associated with approximately the same flows as those measured when boreholes were dewatered during air percussion drilling. We believe the estimates of production during drilling and drawdown tests were similar because partial fracture zone dewatering during drilling prevented larger inflows otherwise expected from the steeper drawdowns during drilling. The fractures and fracture zones indicated on the drilling report and the amounts of water produced by these fractures during drilling generally agree with those identified from the geophysical log analysis. Most water production occurred from two fractured and weathered zones which are separated by an interval of unweathered granite. The fractures identified in the drilling reports show various depth discrepancies in comparison to the geophysical logs, which are subject to much better depth control. However, the depths of the fractures associated with water production on the drilling report are comparable to the depths of the fractures shown to be the source of water inflow in the geophysical log analysis. Other differences in the relative contribution of flow from fracture zones may by attributed to the differences between the hydraulic conditions during drilling, which represent large, prolonged drawdowns, and pumping tests, which consisted of smaller drawdowns

Geochemical Monitoring Of The Gas Hydrate Production By CO2/CH4 Exchange In The Ignik Sikumi Gas Hydrate Production Test Well, Alaska North Slope

NASA Astrophysics Data System (ADS)

Lorenson, T. D.; Collett, T. S.; Ignik Sikumi, S.

2012-12-01

Hydrocarbon gases, nitrogen, carbon dioxide and water were collected from production streams at the Ignik Sikumi gas hydrate production test well (TD, 791.6 m), drilled on the Alaska North Slope. The well was drilled to test the feasibility of producing methane by carbon dioxide injection that replaces methane in the solid gas hydrate. The Ignik Sikumi well penetrated a stratigraphically-bounded prospect within the Eileen gas hydrate accumulation. Regionally, the Eileen gas hydrate accumulation overlies the more deeply buried Prudhoe Bay, Milne Point, and Kuparuk River oil fields and is restricted to the up-dip portion of a series of nearshore deltaic sandstone reservoirs in the Sagavanirktok Formation. Hydrate-bearing sandstones penetrated by Ignik Sikumi well occur in three primary horizons; an upper zone, ("E" sand, 579.7 - 597.4 m) containing 17.7 meters of gas hydrate-bearing sands, a middle zone ("D" sand, 628.2 - 648.6 m) with 20.4 m of gas hydrate-bearing sands and a lower zone ("C" sand, 678.8 - 710.8 m), containing 32 m of gas hydrate-bearing sands with neutron porosity log-interpreted average gas hydrate saturations of 58, 76 and 81% respectively. A known volume mixture of 77% nitrogen and 23% carbon dioxide was injected into an isolated section of the upper part of the "C" sand to start the test. Production flow-back part of the test occurred in three stages each followed by a period of shut-in: (1) unassisted flowback; (2) pumping above native methane gas hydrate stability conditions; and (3) pumping below the native methane gas hydrate stability conditions. Methane production occurred immediately after commencing unassisted flowback. Methane concentration increased from 0 to 40% while nitrogen and carbon dioxide concentrations decreased to 48 and 12% respectively. Pumping above the hydrate stability phase boundary produced gas with a methane concentration climbing above 80% while the carbon dioxide and nitrogen concentrations fell to 2 and 18

Overview of the science activities for the 2002 Mallik gas hydrate production research well program, Mackenzie Delta, N.W.T., Canada

NASA Astrophysics Data System (ADS)

Dallimore, S. R.; Collett, T. S.; Uchida, T.; Weber, M.

2003-04-01

With the completion of scientific studies undertaken as part of the 1998 Mallik 2L-38 gas hydrate research well, an international research site was established for the study of Arctic natural gas hydrates in the Mackenzie Delta of northwestern Canada. Quantitative well log analysis and core studies reveal multiple gas hydrate layers from 890 m to 1106 m depth, exceeding 110 m in total thickness. High gas hydrate saturation values, which in some cases exceed 80% of the pore volume, establish the Mallik gas hydrate field as one of the most concentrated gas hydrate reservoirs in the world. Beginning in December 2001 and continuing to the middle of March 2002, two 1188 m deep science observation wells were drilled and instrumented and a 1166 m deep production research well program was carried out. The program participants include 8 partners; The Geological Survey of Canada (GSC), The Japan National Oil Corporation (JNOC), GeoForschungsZentrum Potsdam (GFZ), United States Geological Survey (USGS), United States Department of the Energy (USDOE), India Ministry of Petroleum and Natural Gas (MOPNG)/Gas Authority of India (GAIL) and the Chevron-BP-Burlington joint venture group. In addition the project has been accepted as part of the International Scientific Continental Drilling Program. The Geological Survey of Canada is coordinating the science program for the project and JAPEX Canada Ltd. acted as the designated operator for the fieldwork. Primary objectives of the research program are to advance fundamental geological, geophysical and geochemical studies of the Mallik gas hydrate field and to undertake advanced production testing of a concentrated gas hydrate reservoir. Full-scale field experiments in the production well monitored the physical behavior of the hydrate deposits in response to depressurization and thermal stimulation. The observation wells facilitated cross-hole tomography and vertical seismic profile experiments (before and after production) as well as

Energy budgeting and carbon footprint of transgenic cotton-wheat production system through peanut intercropping and FYM addition.

PubMed

Singh, Raman Jeet; Ahlawat, I P S

2015-05-01

Two of the most pressing sustainability issues are the depletion of fossil energy resources and the emission of atmospheric green house gases like carbon dioxide to the atmosphere. The aim of this study was to assess energy budgeting and carbon footprint in transgenic cotton-wheat cropping system through peanut intercropping with using 25-50% substitution of recommended dose of nitrogen (RDN) of cotton through farmyard manure (FYM) along with 100% RDN through urea and control (0 N). To quantify the residual effects of previous crops and their fertility levels, a succeeding crop of wheat was grown with varying rates of nitrogen, viz. 0, 50, 100, and 150 kg ha(-1). Cotton + peanut-wheat cropping system recorded 21% higher system productivity which ultimately helped to maintain higher net energy return (22%), energy use efficiency (12%), human energy profitability (3%), energy productivity (7%), carbon outputs (20%), carbon efficiency (17%), and 11% lower carbon footprint over sole cotton-wheat cropping system. Peanut addition in cotton-wheat system increased the share of renewable energy inputs from 18 to 21%. With substitution of 25% RDN of cotton through FYM, share of renewable energy resources increased in the range of 21% which resulted into higher system productivity (4%), net energy return (5%), energy ratio (6%), human energy profitability (74%), energy productivity (6%), energy profitability (5%), and 5% lower carbon footprint over no substitution. The highest carbon footprint (0.201) was recorded under control followed by 50 % substitution of RDN through FYM (0.189). With each successive increase in N dose up to 150 kg N ha(-1) to wheat, energy productivity significantly reduced and share of renewable energy inputs decreased from 25 to 13%. Application of 100 kg N ha(-1) to wheat maintained the highest grain yield (3.71 t ha(-1)), net energy return (105,516 MJ ha(-1)), and human energy profitability (223.4) over other N doses applied to wheat

Environmental behavior of cement-based stabilized foundry sludge products incorporating additives.

PubMed

Ruiz, M C; Irabien, A

2004-06-18

A series of experiments were conducted to stabilize the inorganic and organic pollutants in a foundry sludge from a cast iron activity using Portland cement as binder and three different types of additives, organophilic bentonite, lime and coal fly ash. Ecotoxicological and chemical behavior of stabilized mixes of foundry sludge were analyzed to assess the feasibility to immobilize both types of contaminants, all determined on the basis of compliance leaching tests. The incorporation of lime reduces the ecotoxicity of stabilized mixes and enhances stabilization of organic pollutants obtaining better results when a 50% of cement is replaced by lime. However, the alkalinity of lime increases slightly the leached zinc up to concentrations above the limit set under neutral conditions by the European regulations. The addition of organophilic bentonite and coal fly ash can immobilize the phenolic compounds but are inefficient to reduce the ecotoxicity and mobility of zinc of final products.

Self-reported sitting time and physical activity: interactive associations with mental well-being and productivity in office employees.

PubMed

Puig-Ribera, Anna; Martínez-Lemos, Iván; Giné-Garriga, Maria; González-Suárez, Ángel Manuel; Bort-Roig, Judit; Fortuño, Jesús; Muñoz-Ortiz, Laura; McKenna, Jim; Gilson, Nicholas D

2015-01-31

Little is known about how sitting time, alone or in combination with markers of physical activity (PA), influences mental well-being and work productivity. Given the need to develop workplace PA interventions that target employees' health related efficiency outcomes; this study examined the associations between self-reported sitting time, PA, mental well-being and work productivity in office employees. Descriptive cross-sectional study. Spanish university office employees (n = 557) completed a survey measuring socio-demographics, total and domain specific (work and travel) self-reported sitting time, PA (International Physical Activity Questionnaire short version), mental well-being (Warwick-Edinburg Mental Well-Being Scale) and work productivity (Work Limitations Questionnaire). Multivariate linear regression analyses determined associations between the main variables adjusted for gender, age, body mass index and occupation. PA levels (low, moderate and high) were introduced into the model to examine interactive associations. Higher volumes of PA were related to higher mental well-being, work productivity and spending less time sitting at work, throughout the working day and travelling during the week, including the weekends (p < 0.05). Greater levels of sitting during weekends was associated with lower mental well-being (p < 0.05). Similarly, more sitting while travelling at weekends was linked to lower work productivity (p < 0.05). In highly active employees, higher sitting times on work days and occupational sitting were associated with decreased mental well-being (p < 0.05). Higher sitting times while travelling on weekend days was also linked to lower work productivity in the highly active (p < 0.05). No significant associations were observed in low active employees. Employees' PA levels exerts different influences on the associations between sitting time, mental well-being and work productivity. The specific associations and the broad sweep of evidence in

Improvements in nanoscale zero-valent iron production by milling through the addition of alumina

NASA Astrophysics Data System (ADS)

Ribas, D.; Cernik, M.; Martí, V.; Benito, J. A.

2016-07-01

A new milling procedure for a cost-effective production of nanoscale zero-valent iron for environmental remediation is presented. Conventional ball milling of iron in an organic solvent as Mono Ethylene Glycol produces flattened iron particles that are unlikely to break even after very long milling times. With the aim of breaking down these iron flakes, in this new procedure, further milling is carried out by adding an amount of fine alumina powder to the previously milled solution. As the amount of added alumina increases from 9 to 54 g l-1, a progressive decrease of the presence of flakes is observed. In the latter case, the appearance of the particles formed by fragments of former flakes is rather homogeneous, with most of the final nanoparticles having an equivalent diameter well below 1 µm and with an average particle size in solution of around 400 nm. An additional increase of alumina content results in a highly viscous solution showing worse particle size distribution. Milled particles, in the case of alumina concentrations of 54 g l-1, have a fairly large specific surface area and high Fe(0) content. These new particles show a very good Cr(VI) removal efficiency compared with other commercial products available. This good reactivity is related to the absence of an oxide layer, the large amount of superficial irregularities generated by the repetitive fracture process during milling and the presence of a fine nanostructure within the iron nanoparticles.

Nutrient and acetate amendment leads to acetoclastic methane production and microbial community change in a non-producing Australian coal well.

PubMed

In 't Zandt, Michiel H; Beckmann, Sabrina; Rijkers, Ruud; Jetten, Mike S M; Manefield, Mike; Welte, Cornelia U

2017-09-19

Coal mining is responsible for 11% of total anthropogenic methane emission thereby contributing considerably to climate change. Attempts to harvest coalbed methane for energy production are challenged by relatively low methane concentrations. In this study, we investigated whether nutrient and acetate amendment of a non-producing sub-bituminous coal well could transform the system to a methane source. We tracked cell counts, methane production, acetate concentration and geochemical parameters for 25 months in one amended and one unamended coal well in Australia. Additionally, the microbial community was analysed with 16S rRNA gene amplicon sequencing at 17 and 25 months after amendment and complemented by metagenome sequencing at 25 months. We found that cell numbers increased rapidly from 3.0 × 10 4 cells ml -1 to 9.9 × 10 7 in the first 7 months after amendment. However, acetate depletion with concomitant methane production started only after 12-19 months. The microbial community was dominated by complex organic compound degraders (Anaerolineaceae, Rhodocyclaceae and Geobacter spp.), acetoclastic methanogens (Methanothrix spp.) and fungi (Agaricomycetes). Even though the microbial community had the functional potential to convert coal to methane, we observed no indication that coal was actually converted within the time frame of the study. Our results suggest that even though nutrient and acetate amendment stimulated relevant microbial species, it is not a sustainable way to transform non-producing coal wells into bioenergy factories. © 2017 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology.

Effect of the chlortetracycline addition method on methane production from the anaerobic digestion of swine wastewater.

PubMed

Huang, Lu; Wen, Xin; Wang, Yan; Zou, Yongde; Ma, Baohua; Liao, Xindi; Liang, Juanboo; Wu, Yinbao

2014-10-01

Effects of antibiotic residues on methane production in anaerobic digestion are commonly studied using the following two antibiotic addition methods: (1) adding manure from animals that consume a diet containing antibiotics, and (2) adding antibiotic-free animal manure spiked with antibiotics. This study used chlortetracycline (CTC) as a model antibiotic to examine the effects of the antibiotic addition method on methane production in anaerobic digestion under two different swine wastewater concentrations (0.55 and 0.22mg CTC/g dry manure). The results showed that CTC degradation rate in which manure was directly added at 0.55mg CTC/g (HSPIKE treatment) was lower than the control values and the rest of the treatment groups. Methane production from the HSPIKE treatment was reduced (p<0.05) by 12% during the whole experimental period and 15% during the first 7days. The treatments had no significant effect on the pH and chemical oxygen demand value of the digesters, and the total nitrogen of the 0.55mg CTC/kg manure collected from mediated swine was significantly higher than the other values. Therefore, different methane production under different antibiotic addition methods might be explained by the microbial activity and the concentrations of antibiotic intermediate products and metabolites. Because the primary entry route of veterinary antibiotics into an anaerobic digester is by contaminated animal manure, the most appropriate method for studying antibiotic residue effects on methane production may be using manure from animals that are given a particular antibiotic, rather than adding the antibiotic directly to the anaerobic digester. Copyright © 2014. Published by Elsevier B.V.

Hydrogen sulfide production by sulfate-reducing bacteria utilizing additives eluted from plastic resins.

PubMed

Tsuchida, Daisuke; Kajihara, Yusuke; Shimidzu, Nobuhiro; Hamamura, Kengo; Nagase, Makoto

2011-06-01

In the present study it was demonstrated that organic additives eluted from plastic resins could be utilized as substrates by sulfate-reducing bacteria. Two laboratory-scale experiments, a microcosm experiment and a leaching experiment, were conducted using polyvinyl chloride (PVC) as a model plastic resin. In the former experiment, the conversion of sulfate to sulfide was evident in microcosms that received plasticized PVC as the sole carbon source, but not in those that received PVC homopolymer. Additionally, dissolved organic carbon accumulated only in microcosms that received plasticized PVC, indicating that the dissolved organic carbon originated from additives. In the leaching experiment, phenol and bisphenol A were found in the leached solutions. These results suggest that the disposal of waste plastics in inert waste landfills may result in the production of H(2)S.

A first screening and risk assessment of pharmaceuticals and additives in personal care products in waste water, sludge, recipient water and sediment from Faroe Islands, Iceland and Greenland.

PubMed

Huber, Sandra; Remberger, Mikael; Kaj, Lennart; Schlabach, Martin; Jörundsdóttir, Hrönn Ó; Vester, Jette; Arnórsson, Mímir; Mortensen, Inge; Schwartson, Richard; Dam, Maria

2016-08-15

A screening of a broad range of pharmaceuticals and additives in personal care products (PPCPs) in sub-arctic locations of the Faroe Islands (FO), Iceland (IS) and Greenland (GL) was conducted. In total 36 pharmaceuticals including some metabolites, and seven additives in personal care products were investigated in influent and effluent waters as well as sludge of waste water treatment plants (WWTPs) and in water and sediment of recipients. Concentrations and distribution patterns for PPCPs discharged via sewage lines (SLs) to the marine environment were assessed. Of the 36 pharmaceuticals or metabolites analysed 33 were found close to or above the limit of detection (LOD) in all or a part of the samples. All of the seven investigated additives in personal care products were detected above the LOD. Some of the analysed PPCPs occurred in every or almost every sample. Among these were diclofenac, ibuprofen, lidocaine, naproxen, metformin, citalopram, venlafaxine, amiloride, furosemide, metoprolol, sodium dodecyl sulphate (SDS) and cetrimonium salt (ATAC-C16). Additionally, the study encompasses ecotoxicological risk assessment of 2/3 of the analysed PPCPs in recipient and diluted effluent waters. For candesartan only a small margin to levels with inacceptable risks was observed in diluted effluent waters at two locations (FO). Chronical risks for aquatic organisms staying and/or living around WWTP effluent pipe-outlets were indicated for 17β-estradiol and estriol in the three countries. Additives in PCPs were found to pose the largest risk to the aquatic environment. The surfactants CAPB and ATAC-C16 were found in concentrations resulting in risk factors up to 375 for CAPB and 165 for ATAC-C16 in recipients for diluted effluents from Iggia, Nuuk (GL) and Torshavn (FO) respectively. These results demonstrates a potentially high ecological risk stemming from discharge of surfactants as used in household and industrial detergents as well as additives in personal care

Epigenetic Manipulation of a Filamentous Fungus by the Proteasome-Inhibitor Bortezomib Induces the Production of an Additional Secondary Metabolite.

PubMed

VanderMolen, Karen M; Darveaux, Blaise A; Chen, Wei-Lun; Swanson, Steven M; Pearce, Cedric J; Oberlies, Nicholas H

2014-01-01

The use of epigenetic modifiers, such as histone deacetylase inhibitors and DNA methyltransferase inhibitors, has been explored increasingly as a technique to induce the production of additional microbial secondary metabolites. The application of such molecules to microbial cultures has been shown to upregulate otherwise suppressed genes, and in several cases has led to the production of new molecular structures. In this study, the proteasome inhibitor bortezomib was used to induce the production of an additional metabolite from a filamentous fungus (Pleosporales). The induced metabolite was previously isolated from a plant, but the configuration was not assigned until now; in addition, an analogue was isolated from a degraded sample, yielding a new compound. Proteasome inhibitors have not previously been used in this application and offer an additional tool for microbial genome mining.

[Trends in the utilization of food additives].

PubMed

Szűcs, Viktória; Bánáti, Diána

2013-11-17

The frequent media reports on food additives weakened consumers' trust in food producers and food control authorities as well. Furthermore, consumers' uncertainty is also raised by the fact that they obtain their information from inadequate, mistrustful sources and, therefore, consumers might avoid the consumption of certain foodstuffs. While food producers may react by replacing artificial components by natural ones, they try to emphasize the favourable characteristics of their products. The authors describe the main trends and efforts related to food additives. On the basis of the overview it can be concluded that - besides taking into consideration consumers' needs - product development and research directions are promising. Food producers' efforts may help to restore consumer confidence and trust and they may help them to have informed choice.

Dropwise additive manufacturing of pharmaceutical products for solvent-based dosage forms.

PubMed

Hirshfield, Laura; Giridhar, Arun; Taylor, Lynne S; Harris, Michael T; Reklaitis, Gintaras V

2014-02-01

In recent years, the US Food and Drug Administration has encouraged pharmaceutical companies to develop more innovative and efficient manufacturing methods with improved online monitoring and control. Mini-manufacturing of medicine is one such method enabling the creation of individualized product forms for each patient. This work presents dropwise additive manufacturing of pharmaceutical products (DAMPP), an automated, controlled mini-manufacturing method that deposits active pharmaceutical ingredients (APIs) directly onto edible substrates using drop-on-demand (DoD) inkjet printing technology. The use of DoD technology allows for precise control over the material properties, drug solid state form, drop size, and drop dynamics and can be beneficial in the creation of high-potency drug forms, combination drugs with multiple APIs or individualized medicine products tailored to a specific patient. In this work, DAMPP was used to create dosage forms from solvent-based formulations consisting of API, polymer, and solvent carrier. The forms were then analyzed to determine the reproducibility of creating an on-target dosage form, the morphology of the API of the final form and the dissolution behavior of the drug over time. DAMPP is found to be a viable alternative to traditional mass-manufacturing methods for solvent-based oral dosage forms. © 2013 Wiley Periodicals, Inc. and the American Pharmacists Association.

Effects of resource addition on recovery of production and plant functional composition in degraded semiarid grasslands.

PubMed

Chen, Qing; Hooper, David U; Li, Hui; Gong, Xiao Ying; Peng, Fei; Wang, Hong; Dittert, Klaus; Lin, Shan

2017-05-01

Degradation of semiarid ecosystems from overgrazing threatens a variety of ecosystem services. Rainfall and nitrogen commonly co-limit production in semiarid grassland ecosystems; however, few studies have reported how interactive effects of precipitation and nitrogen addition influence the recovery of grasslands degraded by overgrazing. We conducted a 6-year experiment manipulating precipitation (natural precipitation and simulated wet year precipitation) and nitrogen (0, 25 and 50 kg N ha -1 ) addition at two sites with different histories of livestock grazing (moderately and heavily grazed) in Inner Mongolian steppe. Our results suggest that recovery of plant community composition and recovery of production can be decoupled. Perennial grasses provide long-term stability of high-quality forage production in this system. Supplemental water combined with exclosures led, in the heavily grazed site, to the strongest recovery of perennial grasses, although widespread irrigation of rangeland is not a feasible management strategy in many semiarid and arid regions. N fertilization combined with exclosures, but without water addition, increased dominance of unpalatable annual species, which in turn retarded growth of perennial species and increased inter-annual variation in primary production at both sites. Alleviation of grazing pressure alone allowed recovery of desired perennial species via successional processes in the heavily grazed site. Our experiments suggest that recovery of primary production and desirable community composition are not necessarily correlated. The use of N fertilization for the management of overgrazed grassland needs careful and systematic evaluation, as it has potential to impede, rather than aid, recovery.

Integrity of production wells and confining unit at the Naval Weapons Industrial Reserve Plant, Dallas, Texas, 1995

USGS Publications Warehouse

Jones, Sonya A.; Paillet, Frederick L.

1997-01-01

The results of borehole geophysical log analysis indicate that two of the production wells could have vertically connected intervals where cement bonding in the well annulus is poor. The other production wells have overall good bonding. Temperature logs do not indicate flow behind casing except in the screened interval of one well. Geophysical logs show the Eagle Ford Shale ranges from 147 to 185 feet thick at the site. The Eagle Ford Shale has low permeability and a high plasticity index. These physical characteristics make the Eagle Ford Shale an excellent confining unit.

30 CFR 250.1159 - May the Regional Supervisor limit my well or reservoir production rates?

Code of Federal Regulations, 2011 CFR

2011-07-01

... reservoir production rates? 250.1159 Section 250.1159 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE... Supervisor limit my well or reservoir production rates? (a) The Regional Supervisor may set a Maximum...

Production of high-quality polydisperse construction mixes for additive 3D technologies.

NASA Astrophysics Data System (ADS)

Gerasimov, M. D.; Brazhnik, Yu V.; Gorshkov, P. S.; Latyshev, S. S.

2018-03-01

The paper describes a new design of a mixer allowing production of high quality polydisperse powders, used in additive 3D technologies. A new principle of dry powder particle mixing is considered, implementing a possibility of a close-to-ideal distribution of such particles in common space. A mathematical model of the mixer is presented, allowing evaluating quality indicators of the produced mixture. Experimental results are shown and rational values of process parameters of the mixer are obtained.

Influence of Wheat-Milled Products and Their Additive Blends on Pasta Dough Rheological, Microstructure, and Product Quality Characteristics

PubMed Central

Dhiraj, B.; Prabhasankar, P.

2013-01-01

This study is aimed to assess the suitability of T. aestivum wheat milled products and its combinations with T. durum semolina with additives such as ascorbic acid, vital gluten and HPMC (Hydroxypropyl methyl cellulose) for pasta processing quality characteristics such as pasta dough rheology, microstructure, cooking quality, and sensory evaluation. Rheological studies showed maximum dough stability in Comb1 (T. aestivum wheat flour and semolina). Colour and cooking quality of Comb2 (T. durum semolina and T. aestivum wheat flour) and Comb3 (T. aestivum wheat semolina and T. durum semolina) were comparable with control. Pasting results indicated that T. aestivum semolina gave the lowest onset gelatinization temperature (66.9°C) but the highest peak viscosity (1.053 BU). Starch release was maximum in Comb1 (53.45%) when compared with control (44.9%) as also proved by microstructure studies. Firmness was seen to be slightly high in Comb3 (2.430 N) when compared with control (2.304 N), and sensory evaluations were also in the acceptable range for the same. The present study concludes that Comb3 comprising 50% T. durum semolina and 50% T. aestivum refined wheat flour with additives would be optimal alternate for 100% T. durum semolina for production of financially viable pasta. PMID:26904601

Examination of the jarosite-alunite precipitate addition in the raw meal for the production of sulfoaluminate cement clinker.

PubMed

Katsioti, M; Tsakiridis, P E; Leonardou-Agatzini, S; Oustadakis, P

2006-04-17

The aim of the present research work was to investigate the possibility of adding a jarosite-alunite chemical precipitate, a waste product of a new hydrometallurgical process developed to treat economically low-grade nickel oxides ores, in the raw meal for the production of sulfoaluminate cement clinker. For that reason, two samples of raw meals were prepared, one contained 20% gypsum, as a reference sample ((SAC)Ref) and another with 11.31% jarosite-alunite precipitate ((SAC)J/A). Both raw meals were sintered at 1300 degrees C. The results of chemical and mineralogical analyses as well as the microscopic examination showed that the use of the jarosite-alunite precipitate did not affect the mineralogical characteristics of the so produced sulfoaluminate cement clinker and there was confirmed the formation of the sulfoaluminate phase (C4A3S), the most typical phase of this cement type. Furthermore, both clinkers were tested by determining the grindability, setting time, compressive strength and expansibility. The hydration products were examined by XRD analysis at 2, 7, 28 and 90 days. The results of the physico-mechanical tests showed that the addition of jarosite-alunite precipitate did not negatively affect the quality of the produced cement.

Diastereoselective addition of Grignard reagents to α-epoxy N-sulfonyl hydrazones

NASA Astrophysics Data System (ADS)

Uteuliyev, Maulen M.; Nguyen, Thien T.; Coltart, Don M.

2015-12-01

The α-alkylation of ketones and their derivatives by the addition of their corresponding enolates to alkyl halides is a fundamental synthetic transformation, but its utility is limited because the key bond-forming step proceeds in a bimolecular nucleophilic substitution fashion. Here we describe how an umpolung strategy that involves the addition of Grignard reagents to α-epoxy N-sulfonyl hydrazones—directed by the alkoxide of the 1-azo-3-alkoxy propenes formed in situ via base-induced ring opening of the epoxide—leads to the syn-selective production of α-alkyl-β-hydroxy N-sulfonyl hydrazones with α-quaternary centres. This transformation is remarkable in its ability to incorporate an unprecedented range of carbon-based substituents, which include primary, secondary and tertiary alkyl, as well as alkenyl, aryl, allenyl and alkynyl groups. Subsequent hydrolysis of the β-hydroxy N-sulfonyl hydrazone products produces the corresponding β-hydroxy ketones. In addition to hydrolysis, the hydrazone products are poised to undergo numerous different known synthetic transformations via well-established chemistry, which would provide access to a wide array of useful structures.

THE CARCINOGENIC RESPONSE TO A MIXTURE OF DRINKING WATER DISINFECTION BY-PRODUCTS (DBP) WAS LESS THAN ADDITIVE

EPA Science Inventory

THE CARCINOGENIC RESPONSE TO A MIXTURE OF DRINKING WATER DISINFECTION BY -PRODUCTS (DBP) W AS LESS THAN ADDITIVE.

Current default risk assessments for chemical mixtures assume additivity of carcinogenic effects but this may under or over represent the actual biological res...

Antibacterial Activity of Probiotic Lactobacillus plantarum HK01: Effect of Divalent Metal Cations and Food Additives on Production Efficiency of Antibacterial Compounds.

PubMed

Sharafi, Hakimeh; Alidost, Leila; Lababpour, Abdolmajid; Shahbani Zahiri, Hossein; Abbasi, Habib; Vali, Hojatollah; Akbari Noghabi, Kambiz

2013-06-01

One hundred and sixty lactic acid bacteria, isolated from Iranian traditional dairy products, were screened for antibacterial potential. Among them, an isolate showing remarkable antibacterial activity against both Staphylococcus aureus (PTCC 1112) and Escherichia coli (PTCC 1338) was selected based on minimum inhibitory concentration (AU/mL). The morphological and biochemical characteristics of the isolate matched the literature description about genus Lactobacillus. Partial sequencing of 16S rRNA gene and its alignment with other Lactobacillus strains revealed that the isolate was closely related to the Lactobacillus plantarum. The isolate also exhibited the highest similarity (>99 %) to L. plantarum. We thus tentatively classified the bacterial isolate as L. plantarum HK01. The antibacterial active compound from HK01 strain remained stable for 45 min at 121 °C, and it reached a maximum activity at the end of log phase and the early part of stationary phase. The antibacterial activity of the test isolate, its probiotic properties and production efficacy through addition of some divalent metal cations and food additives were studied as well. The study of bile salt hydrolase (BSH) activity as a function of growth revealed that HK01 strain hydrolysing up to 5 % of sodium salt of glycodeoxycholic acid, correlated with the presence of bsh gene in the isolate. HK01 strain showed high resistance to lysozyme, good adaptation to simulated gastric juice and a moderate bile tolerance. Results obtained from simulated gastric juice conditions showed no significant difference occured during the 70 min. HK01 strain was classified as a strain with low hydrophobicity (34.2 %). Addition of trisodium citrate dehydrates as a food-grade chelator of divalent cations restored antibacterial compound production in MRS broth. Antibacterial compounds of L. plantarum HK01 endured treatment with 10 g/L of SDS, Tween 20, Tween 80 and urea. Concerning food additives, the results

An inventory of methods suitable to assess additive-induced characterising flavours of tobacco products.

PubMed

Talhout, Reinskje; van de Nobelen, Suzanne; Kienhuis, Anne S

2016-04-01

Products with strong non-tobacco flavours are popular among young people, and facilitate smoking initiation. Similar to the U.S. Food and Drug Administration Tobacco Control Act, the new European Tobacco Product Directive (TPD) prohibits cigarettes and roll-your-own tobacco with a characterising flavour other than tobacco. However, no methods are prescribed or operational to assess characterising flavours. This is the first study to identify, review and synthesize the existing peer-reviewed and tobacco industry literature in order to provide an inventory of methods suitable to assess characterising flavours. Authors gathered key empirical and theoretical papers examining methods suitable to assess characterising flavours. Scientific literature databases (PubMed and Scopus) and tobacco industry documents were searched, based on several keyword combinations. Inclusion criteria were relevance for smoked tobacco products, and quality of data. The findings reveal that there is a wide variation in natural tobacco flavours. Flavour differences from natural tobacco can be described by both expert and consumer sensory panels. Most methods are based on smoking tests, but odour evaluation has also been reported. Chemical analysis can be used to identify and quantify levels of specific flavour additives in tobacco products. As flavour perception is subjective, and requires human assessment, sensory analysis in consumer or expert panel studies is necessitated. We recommend developing validated tests for descriptive sensory analysis in combination with chemical-analytical measurements. Testing a broad range of brands, including those with quite subtle characterizing flavours, will provide the concentration above which an additive will impart a characterising flavour. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Productive Activities and Subjective Well-Being among Older Adults: The Influence of Number of Activities and Time Commitment

ERIC Educational Resources Information Center

Baker, Lindsey A.; Cahalin, Lawrence P.; Gerst, Kerstin; Burr, Jeffrey A.

2005-01-01

This study examines relationships among three measures of subjective well-being (life satisfaction, happiness and depressive symptoms), and two global measures of productive activity (number of activities and time commitment). We argue that participation in multiple productive activities should increase subjective well-being because these…

Regulation of metabolic products and gene expression in Fusarium asiaticum by agmatine addition.

PubMed

Suzuki, Tadahiro; Kim, Young-Kyung; Yoshioka, Hifumi; Iwahashi, Yumiko

2013-05-01

The metabolic products resulting from the cultivation of F. asiaticum in agmatine were identified using capillary electrophoresis-time of flight mass spectrometry. Glyoxylic acid was detected from fungal cultures grown in agmatine, while it was absent in control cells. The abundance of other metabolic products of the glycolytic pathway also increased because of agmatine; however, there was no increase in the amounts of pyruvic acid or metabolites from the tricarboxylic acid cycle. Moreover, gene expression levels within Fusarium asiaticum exposed to agmatine were analyzed by DNA microarray. Changes in gene expression levels directed the changes in metabolic products. Our results suggest that acetyl coenzyme A, which is a starting substrate for the biosynthesis of deoxynivalenol (DON), was simultaneously produced by activated β-oxidation. Furthermore, the content of 4-aminobutyrate (GABA) was increased in the agmatine addition culture medium. GABA can be synthesized from agmatine through putrescine and might influence the regulation of DON-related genes.

Water based drilling mud additive

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCrary, J.L.

1983-12-13

A water based fluid additive useful in drilling mud used during drilling of an oil or gas well is disclosed, produced by reacting water at temperatures between 210/sup 0/-280/sup 0/ F. with a mixture comprising in percent by weight: gilsonite 25-30%, tannin 7-15%, lignite 25-35%, sulfonating compound 15-25%, water soluble base compound 5-15%, methylene-yielding compound 1-5%, and then removing substantially all of the remaining water to produce a dried product.

The effect of various pozzolanic additives on the concrete strength index

NASA Astrophysics Data System (ADS)

Vitola, L.; Sahmenko, G.; Erdmane, D.; Bumanis, G.; Bajare, D.

2017-10-01

The concrete industry is searching continuously for new effective mineral additives to improve the concrete properties. Replacing cement with the pozzolanic additives in most cases has resulted not only in positive impact on the environment but also has improved strength and durability of the concrete. Effective pozzolanic additives can be obtained from natural resources such as volcanic ashes, kaolin and other sediments as well as from different production industries that create various by-products with high pozzolanic reactivity. Current research deals with effectiveness evaluation of various mineral additives/wastes, such as coal combustion bottom ash, barley bottom ash, waste glass and metakaolin containing waste as well as calcined illite clays as supplementary cementitious materials, to be used in concrete production as partial cement replacement. Most of the examined materials are used as waste stream materials with potential reactive effect on the concrete. Milling time and fineness of the tested supplementary material has been evaluated and effectiveness was detected. Results indicate that fineness of the tested materials has crucial effect on the concrete compressive strength index. Not in all cases the prolonged milling time can increase fineness and reactivity of the supplementary materials; however the optimal milling time and fineness of the pozolanic additives increased the strength index of concrete up to 1.16 comparing to reference, even in cases when cement was substituted by 20 w%.

Relative Contribution of nirK- and nirS- Bacterial Denitrifiers as Well as Fungal Denitrifiers to Nitrous Oxide Production from Dairy Manure Compost.

PubMed

Maeda, Koki; Toyoda, Sakae; Philippot, Laurent; Hattori, Shohei; Nakajima, Keiichi; Ito, Yumi; Yoshida, Naohiro

2017-12-19

The relative contribution of fungi, bacteria, and nirS and nirK denirifiers to nitrous oxide (N 2 O) emission with unknown isotopic signature from dairy manure compost was examined by selective inhibition techniques. Chloramphenicol (CHP), cycloheximide (CYH), and diethyl dithiocarbamate (DDTC) were used to suppress the activity of bacteria, fungi, and nirK-possessing denitrifiers, respectively. Produced N 2 O were surveyed to isotopocule analysis, and its 15 N site preference (SP) and δ 18 O values were compared. Bacteria, fungi, nirS, and nirK gene abundances were compared by qPCR. The results showed that N 2 O production was strongly inhibited by CHP addition in surface pile samples (82.2%) as well as in nitrite-amended core samples (98.4%), while CYH addition did not inhibit the N 2 O production. N 2 O with unknown isotopic signature (SP = 15.3-16.2‰), accompanied by δ 18 O (19.0-26.8‰) values which were close to bacterial denitrification, was also suppressed by CHP and DDTC addition (95.3%) indicating that nirK denitrifiers were responsible for this N 2 O production despite being less abundant than nirS denitrifiers. Altogether, our results suggest that bacteria are important for N 2 O production with different SP values both from compost surface and pile core. However, further work is required to decipher whether N 2 O with unknown isotopic signature is mostly due to nirK denitrifiers that are taxonomically different from the SP-characterized strains and therefore have different SP values rather than also being interwoven with the contribution of the NO-detoxifying pathway and/or of co-denitrification.

Associating cooking additives with sodium hydroxide to pretreat bamboo residues for improving the enzymatic saccharification and monosaccharides production.

PubMed

Huang, Caoxing; He, Juan; Wang, Yan; Min, Douyong; Yong, Qiang

2015-10-01

Cooking additive pulping technique is used in kraft mill to increase delignification degree and pulp yield. In this work, cooking additives were firstly applied in the sodium hydroxide pretreatment for improving the bioconversion of bamboo residues to monosaccharides. Meanwhile, steam explosion and sulfuric acid pretreatments were also carried out on the sample to compare their impacts on monosaccharides production. Results indicated that associating anthraquinone with sodium hydroxide pretreatment showed the best performance in improving the original carbohydrates recovery, delignification, enzymatic saccharification, and monosaccharides production. After consecutive pretreatment and enzymatic saccharification process, 347.49 g, 307.48 g, 142.93 g, and 87.15 g of monosaccharides were released from 1000 g dry bamboo residues pretreated by sodium hydroxide associating with anthraquinone, sodium hydroxide, steam explosion and sulfuric acid, respectively. The results suggested that associating cooking additive with sodium hydroxide is an effective pretreatment for bamboo residues to enhance enzymatic saccharification for monosaccharides production. Copyright © 2015 Elsevier Ltd. All rights reserved.

Trends in hydraulic fracturing distributions and treatment fluids, additives, proppants, and water volumes applied to wells drilled in the United States from 1947 through 2010: data analysis and comparison to the literature

USGS Publications Warehouse

Gallegos, Tanya J.; Varela, Brian A.

2015-01-01

Hydraulic fracturing is presently the primary stimulation technique for oil and gas production in low-permeability, unconventional reservoirs. Comprehensive, published, and publicly available information regarding the extent, location, and character of hydraulic fracturing in the United States is scarce. This national spatial and temporal analysis of data on nearly 1 million hydraulically fractured wells and 1.8 million fracturing treatment records from 1947 through 2010 (aggregated in Data Series 868) is used to identify hydraulic fracturing trends in drilling methods and use of proppants, treatment fluids, additives, and water in the United States. These trends are compared to the literature in an effort to establish a common understanding of the differences in drilling methods, treatment fluids, and chemical additives and of how the newer technology has affected the water use volumes and areal distribution of hydraulic fracturing. Historically, Texas has had the highest number of records of hydraulic fracturing treatments and associated wells in the United States documented in the datasets described herein. Water-intensive horizontal/directional drilling has also increased from 6 percent of new hydraulically fractured wells drilled in the United States in 2000 to 42 percent of new wells drilled in 2010. Increases in horizontal drilling also coincided with the emergence of water-based “slick water” fracturing fluids. As such, the most current hydraulic fracturing materials and methods are notably different from those used in previous decades and have contributed to the development of previously inaccessible unconventional oil and gas production target areas, namely in shale and tight-sand reservoirs. Publicly available derivative datasets and locations developed from these analyses are described.

SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scott Reeves

2003-03-01

Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Completed both type curve and artificial neural network analysis of the field. Developed list of production enhancement candidates. (2) Made final presentation of results to Oneok in Tulsa (February 26). (3) Made

Drilling mud additives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roemer, P.; Downhour, R. Jr.

1970-06-30

A drilling mud additive prepared from farinaceous material contains relatively high gluten and fat contents and has between 30 and 40% water soluble solids on a dry basis. The product is particularly useful in rotary drilling as an additive to the drilling mud to inhibit water loss. The key to achieving the desired product is pretreatment of the raw flour and control of moisture. (2 claims)

A non-additive repulsive contribution in an equation of state: The development for homonuclear square well chains equation of state validated against Monte Carlo simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Trinh, Thi-Kim-Hoang; Laboratoire de Science des Procédés et des Matériaux; Passarello, Jean-Philippe, E-mail: Jean-Philippe.Passarello@lspm.cnrs.fr

This work consists of the adaptation of a non-additive hard sphere theory inspired by Malakhov and Volkov [Polym. Sci., Ser. A 49(6), 745–756 (2007)] to a square-well chain. Using the thermodynamic perturbation theory, an additional term is proposed that describes the effect of perturbing the chain of square well spheres by a non-additive parameter. In order to validate this development, NPT Monte Carlo simulations of thermodynamic and structural properties of the non-additive square well for a pure chain and a binary mixture of chains are performed. Good agreements are observed between the compressibility factors originating from the theory and thosemore » from molecular simulations.« less

15 CFR 714.3 - Advance declaration requirements for additionally planned production of Schedule 3 chemicals.

Code of Federal Regulations, 2010 CFR

2010-01-01

... additionally planned production of Schedule 3 chemicals. 714.3 Section 714.3 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 3 CHEMICALS § 714.3 Advance...

The effects of chemical additives on the production of disinfection byproducts and ecotoxicity in simulated ballast water

NASA Astrophysics Data System (ADS)

Park, Chul; Cha, Hyung-Gon; Lee, Ji-Hyun; Choi, Tae Seop; Lee, Jungsuk; Kim, Young-Hee; Bae, Minjung; Shin, Kyoungsoon; Choi, Keun-Hyung

2017-11-01

The management of ship ballast water is essential to stemming the introduction of non-indigenous species. Approval for onboard installation of a system to treat ballast water requires rigorous land-based testing as dictated in the G8 guideline by the International Maritime Organization. However, this testing lacks standardization-most notably augmentation of organic carbon for influent water by adding chemical additives. Electrochlorination is a popular treatment method for ballast water, in which chlorinated oxidants react with organisms and organic matter in water. The additives could thus affect the treatment efficacy of the ballast water. Here, we examined the effects of several candidates of organic carbon additives on the consumption of total residual oxidant (TRO), the production of disinfection byproducts (DBPs), plankton survival, and ecotoxicity. The TRO consumption over five days of storage was higher in electrochlorinated seawater amended with lignin and Metamucil when compared with seawaters with other organic carbon compounds. DBP production varied by almost two orders of magnitude as a function of the various additives. This was largely attributed to the production of tribromomethane and dibromoacetic acid. The survival of Artemia franciscana was significantly different across waters of different organic carbon additives. Algal toxicity testing with the marine haptophyte Isochrysis galbana significantly reduced growth in lignin- and Metamucil-treated seawaters, but not with other organic carbon compounds. Bioluminescence in Vibrio fischeri sharply declined in electrochlorinated seawaters with all types of organic carbon compounds, but no toxicity was manifested once the electrochlorinated seawaters were neutralized with sodium thiosulfate. The varying degrees of outcome suggest that it might be better to eliminate the requirements of adding organic carbon to test water as long as natural water was used for land-based testing of BWMS. If needed, the

Large Scale Metal Additive Techniques Review

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nycz, Andrzej; Adediran, Adeola I; Noakes, Mark W

2016-01-01

In recent years additive manufacturing made long strides toward becoming a main stream production technology. Particularly strong progress has been made in large-scale polymer deposition. However, large scale metal additive has not yet reached parity with large scale polymer. This paper is a review study of the metal additive techniques in the context of building large structures. Current commercial devices are capable of printing metal parts on the order of several cubic feet compared to hundreds of cubic feet for the polymer side. In order to follow the polymer progress path several factors are considered: potential to scale, economy, environmentmore » friendliness, material properties, feedstock availability, robustness of the process, quality and accuracy, potential for defects, and post processing as well as potential applications. This paper focuses on current state of art of large scale metal additive technology with a focus on expanding the geometric limits.« less

75 FR 69705 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Marine Well...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-15

... Production Act of 1993--Marine Well Containment Venture Notice is hereby given that, on September 29, 2010... seq. (``the Act''), Marine Well Containment Venture (``MWCV'') has filed written notifications...Phillips Marine Containment Holdings Co. LLC, Houston, TX; ExxonMobil Offshore Well Containment LLC...

76 FR 43348 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Marine Well...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-20

... Production Act of 1993--Marine Well Containment Venture Notice is hereby given that, on June 7, 2011... seq. (``the Act''), Marine Well Containment Venture (``MWCV'') has filed written notifications... Deepwater LLC, Houston, TX; Anadarko Offshore Well Containment Company LLC, The Woodlands, TX; BHP Billiton...

75 FR 62570 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Marine Well...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-12

... Production Act of 1993--Marine Well Containment Venture Notice is hereby given that, on August 18, 2010... seq. (``the Act''), Marine Well Containment Venture (``MWCV'') has filed written notifications... (assemble and/or construct), operate, maintain, and own a system to provide emergency hydrocarbon well...

76 FR 27351 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Marine Well...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-11

... Production Act of 1993--Marine Well Containment Venture Notice is hereby given that, on March 04, 2011... seq. (``the Act''), Marine Well Containment Venture (``MWCV'') has filed written notifications... objectives, the previously-disclosed parties to MWCV have formed Marine Well Containment Company LLC (``MWCC...

Aerated drilling cutting transport analysis in geothermal well

NASA Astrophysics Data System (ADS)

Wakhyudin, Aris; Setiawan, Deni; Dwi Marjuan, Oscar

2017-12-01

Aeratad drilling widely used for geothermal drilling especially when drilled into predicted production zone. Aerated drilling give better performance on preventing lost circulation problem, improving rate of penetration, and avoiding drilling fluid invasion to productive zone. While well is drilled, cutting is produced and should be carried to surface by drilling fluid. Hole problem, especially pipe sticking will occur while the cutting is not lifted properly to surface. The problem will effect on drilling schedule; non-productive time finally result more cost to be spent. Geothermal formation has different characteristic comparing oil and gas formation. Geothermal mainly has igneous rock while oil and gas mostly sedimentary rock. In same depth, formation pressure in geothermal well commonly lower than oil and gas well while formation temperature geothermal well is higher. While aerated drilling is applied in geothermal well, Igneous rock density has higher density than sedimentary rock and aerated drilling fluid is lighter than water based mud hence minimum velocity requirement to transport cutting is larger than in oil/gas well drilling. Temperature and pressure also has impact on drilling fluid (aerated) density. High temperature in geothermal well decrease drilling fluid density hence the effect of pressure and temperature also considered. In this paper, Aerated drilling cutting transport performance on geothermal well will be analysed due to different rock and drilling fluid density. Additionally, temperature and pressure effect on drilling fluid density also presented to merge.

Organic soil production from urban soil, spent mushroom substrate, and other additives

NASA Astrophysics Data System (ADS)

Pham, Nhung Thi Ha

2017-09-01

In recent years, spent mushroom substrate (SMS) is becoming the huge problem in environmental pollution issues from mushroom production. However, SMS is also a nutrient-rich ogranic material with available nutrients and high porosity. Therefore, the value of products made from SMS should be exploited to take full advantage of agricultural by-product, support organic agriculture development without environmental pollution. The research has built 5 experimental formulas (4 mixed formulas and 1 control formulas with only urban soil). The analysis results of soil samples from mixed formulas and the control formula witness a significant increase in moisture and OM of mixed formulas (moisture from 36-42%, OM from 5.5-6.9%) after 20 treatment days, and N-P-K contents are also improved remarkably. 60 days later, soil nutrients in mixed formulas continue to rise, with highest OM (8.679%) at CT1; N (0.154%) at CT4; K2O (0,698%) and P2O5 (0,172%) at CT3, in addition, heavy metal contents in all formulas are under standard limit. Synthetic assessment of all norms indicates that the best organic soil product comes from CT3. The pak choi planting experiments are performed show that the growth of plants cultivated on organic soil products made from mixed formulas are much better than plants are grown on initially soil, and they also have no pestilent insect. Specially, pak choi planted on organic soil from CT3 have sharp developing with excellent tolerance ability, quantity and area of leaves are high. Thus, CT3 is the most suitable formula to increase soil nutrients, to solve spent mushroom subtrate streament problems after harvest, and for sustainable agricultural development.

Filamentous fungi for production of food additives and processing aids.

PubMed

Archer, David B; Connerton, Ian F; MacKenzie, Donald A

2008-01-01

Filamentous fungi are metabolically versatile organisms with a very wide distribution in nature. They exist in association with other species, e.g. as lichens or mycorrhiza, as pathogens of animals and plants or as free-living species. Many are regarded as nature's primary degraders because they secrete a wide variety of hydrolytic enzymes that degrade waste organic materials. Many species produce secondary metabolites such as polyketides or peptides and an increasing range of fungal species is exploited commercially as sources of enzymes and metabolites for food or pharmaceutical applications. The recent availability of fungal genome sequences has provided a major opportunity to explore and further exploit fungi as sources of enzymes and metabolites. In this review chapter we focus on the use of fungi in the production of food additives but take a largely pre-genomic, albeit a mainly molecular, view of the topic.

Wellness in Small Businesses. WBGH Worksite Wellness Series.

ERIC Educational Resources Information Center

Behrens, Ruth A.

Increasing numbers of small businesses are providing wellness activities for their employees. By instituting wellness programs, small businesses can improve employee morale, engender a commitment from employees, enhance the feeling of "family" among employees, improve worker productivity, and contain health care costs. Wellness programs are…

Thermodynamic evaluation of hydrogen production for fuel cells by using bio-ethanol steam reforming: Effect of carrier gas addition

NASA Astrophysics Data System (ADS)

Hernández, Liliana; Kafarov, Viatcheslav

Omitting the influence of the addition of carrier gas to the reaction system for hydrogen production by bio-ethanol steam reforming can lead to wrong conclusions, especially when it is going to be made to scale. The effect of carrier gas addition to produce hydrogen using bio-ethanol steam reforming to feed fuel cells was evaluated. Thermodynamic calculations in equilibrium conditions were made, however the analysis derived from them can also be applied to kinetic conditions. These calculations were made by using the Aspen-HYSYS software at atmospheric pressure and different values of temperature, water/ethanol molar ratios, and inert (argon)/(water/ethanol) molar ratios. The addition of inert carrier gas modifies the concentrations of the reaction products in comparison to those obtained without its presence. This behavior occurs because most of the reactions which take place in bio-ethanol steam reforming have a positive difference of moles. This fact enhances the system sensitivity to inert concentration at low and moderated temperatures (<700 °C). At high values of temperature, the inert addition does not influence the composition of the reaction products because of the predominant effect of inverse WGS reaction.

Evaluating leachate recirculation with cellulase addition to enhance waste biostabilisation and landfill gas production.

PubMed

Frank, R R; Davies, S; Wagland, S T; Villa, R; Trois, C; Coulon, F

2016-09-01

The effect of leachate recirculation with cellulase augmentation on municipal solid waste (MSW) biostabilisation and landfill gas production was investigated using batch bioreactors to determine the optimal conditions of moisture content, temperature and nutrients. Experimentation was thereafter scaled-up in 7L bioreactors. Three conditions were tested including (1) leachate recirculation only, (2) leachate recirculation with enzyme augmentation and (3) no leachate recirculation (control). Cumulative biogas production of the batch tests indicated that there was little difference between the leachate and control test conditions, producing on average 0.043m(3)biogaskg(-1) waste. However the addition of cellulase at 15×10(6)Utonne(-1) waste doubled the biogas production (0.074m(3)biogaskg(-1) waste). Similar trend was observed with the bioreactors. Cellulase addition also resulted in the highest COD reduction in both the waste and the leachate samples (47% and 42% COD reduction, respectively). In both cases, the quantity of biogas produced was closer to the lower value of theoretical and data-based biogas prediction indicators (0.05-0.4m(3)biogaskg(-1) waste). This was likely due to a high concentration of heavy metals present in the leachate, in particular Cr and Mn, which are known to be toxic to methanogens. The cost-benefit analysis (CBA) based on the settings of the study (cellulase concentration of 15×10(6)Utonne(-1) waste) showed that leachate bioaugmentation using cellulase is economically viable, with a net benefit of approximately €12.1million on a 5Mt mixed waste landfill. Copyright © 2016 Elsevier Ltd. All rights reserved.

Interactive effects of nutrient additions and predation on infaunal communities

USGS Publications Warehouse

Posey, M.H.; Alphin, T.D.; Cahoon, L.; Lindquist, D.; Becker, M.E.

1999-01-01

Nutrient additions represent an important anthropogenic stress on coastal ecosystems. At moderate levels, increased nutrients may lead to increased primary production and, possibly, to increased biomass of consumers although complex trophic interactions may modify or mask these effects. We examined the influence of nutrient additions and interactive effects of trophic interactions (predation) on benthic infaunal composition and abundances through small-scale field experiments in 2 estuaries that differed in ambient nutrient conditions. A blocked experimental design was used that allowed an assessment of direct nutrient effects in the presence and absence of predation by epibenthic predators as well as an assessment of the independent effects of predation. Benthic microalgal production increased with experimental nutrient additions and was greater when infaunal abundances were lower, but there were no significant interactions between these factors. Increased abundances of one infaunal taxa, Laeonereis culveri, as well as the grazer feeding guild were observed with nutrient additions and a number of taxa exhibited higher abundances with predator exclusion. In contrast to results from freshwater systems there were no significant interactive effects between nutrient additions and predator exclusion as was predicted. The infaunal responses observed here emphasize the importance of both bottom-up (nutrient addition and primary producer driven) and top-down (predation) controls in structuring benthic communities. These processes may work at different spatial and temporal scales, and affect different taxa, making observation of potential interactive effects difficult.

Oxidative and inert pyrolysis on-line coupled to gas chromatography with mass spectrometric detection: On the pyrolysis products of tobacco additives.

PubMed

Paschke, Meike; Hutzler, Christoph; Henkler, Frank; Luch, Andreas

2016-11-01

According to European legislation, tobacco additives may not increase the toxicity or the addictive potency of the product, but there is an ongoing debate on how to reliably characterize and measure such properties. Further, too little is known on pyrolysis patterns of tobacco additives to assume that no additional toxicological risks need to be suspected. An on-line pyrolysis technique was used and coupled to gas chromatography-mass spectrometry (GC/MS) to identify the pattern of chemical species formed upon thermal decomposition of 19 different tobacco additives like raw cane sugar, licorice or cocoa. To simulate the combustion of a cigarette it was necessary to perform pyrolysis at inert conditions as well as under oxygen supply. All individual additives were pyrolyzed under inert or oxidative conditions at 350, 700 and 1000°C, respectively, and the formation of different toxicants was monitored. We observed the generation of vinyl acrylate, fumaronitrile, methacrylic anhydride, isobutyric anhydride and 3-buten-2-ol exclusively during pyrolysis of tobacco additives. According to the literature, these toxicants so far remained undetectable in tobacco or tobacco smoke. Further, the formation of 20 selected polycyclic aromatic hydrocarbons (PAHs) with molecular weights of up to 278Da was monitored during pyrolysis of cocoa in a semi-quantitative approach. It was shown that the adding of cocoa to tobacco had no influence on the relative amounts of the PAHs formed. Copyright © 2016 Elsevier GmbH. All rights reserved.

T-F and S/DOE Gladys McCall No. 1 well, Cameron Parish, Louisiana. Geopressured-geothermal well report, Volume II. Well workover and production testing, February 1982-October 1985. Final report. Appendices 1-7

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1985-01-01

These appendices contain the following reports: (1) investigation of coupling failure from the Gladys McCall No. 1 well; (2) failure analysis - oil well casing coupling; (3) technical remedial requirements for 5-inch production tubing string; (4) reservoir limit test data for sand zone No. 9; (5) reservoir fluid study - sand zone No. 9; (6) engineering interpretation of exploration drawdown tests; and (7) reservoir analysis. (ACR)

Alaska forest products: using resources well.

Treesearch

Valerie Rapp

2003-01-01

Despite abundant forest resources in the state, the Alaska forest products industry declined throughout the 1990s and early 21st century. In a state with lots of trees, mills are going out of business and most finished lumber used in the state is imported from the lower 48 United States and Canada. The Alaska Wood Utilization Research and Development Center (Wood...

Spent yeast as natural source of functional food additives

PubMed

Rakowska, Rita; Sadowska, Anna; Dybkowska, Ewa; Świderski, Franciszek

Spent yeasts are by-products arising from beer and wine production which over many years have been chiefly used as feed additives for livestock. They contain many valuable and bioactive substances which has thereby generated much interest in their exploitation. Up till now, the main products obtained from beer-brewing yeasts are β-glucans and yeast extracts. Other like foodstuffs include dried brewer’s yeast, where this is dried and the bitterness removed to be fit for human consumption as well as mannan-oligosaccharides hitherto used in the feed industry. β-glucans constitute the building blocks of yeast cell walls and can thus be used in human nutrition as dietary supplements or serving as food additives in functional foods. β-glucans products obtained via post-fermentation of beer also exhibit a high and multi-faceted biological activity where they improve the blood’s lipid profile, enhance immunological status and have both prebiotic and anti-oxidant properties. Yeast extracts are currently being used more and more to enhance flavour in foodstuffs, particularly for meat and its products. Depending on how autolysis is carried out, it is possible to design extracts of various meat flavours characteristic of specific meats. Many different flavour profiles can be created which may be additionally increased in combination with vegetable extracts. Within the food market, yeast extracts can appear in various guises such as liquids, pastes or powders. They all contain significant amounts of glutamic acid, 5’-GMP and 5’-IMP nucleotides together with various amino acids and peptides that act synergistically for enhancing the flavour of foodstuff products. Recent studies have demonstrated additional benefits of yeast extracts as valuable sources of amino acids and peptides which can be used in functional foods and dietary supplements. These products possess GRAS status (Generally Recognised As Safe) which thereby also adds further as to why they should be used

Production of monozygotic twin calves using the blastomere separation technique and Well of the Well culture system.

PubMed

Tagawa, M; Matoba, S; Narita, M; Saito, N; Nagai, T; Imai, K

2008-03-15

The present study was conducted to establish a simple and efficient method of producing monozygotic twin calves using the blastomere separation technique. To produce monozygotic twin embryos from zona-free two- and eight-cell embryos, blastomeres were separated mechanically by pipetting to form two demi-embryos; each single blastomere from the two-cell embryo and tetra-blastomeres from the eight-cell embryo were cultured in vitro using the Well of the Well culture system (WOW). This culture system supported the successful arrangement of blastomeres, resulting in their subsequent aggregation to form a demi-embryo developing to the blastocyst stage without a zona pellucida. There was no significant difference in the development to the blastocyst stage between blastomeres separated from eight-cell (72.0%) and two-cell (62.0%) embryos. The production rates of the monozygotic pair blastocysts and transferable paired blastocysts for demi-embryos obtained from eight-cell embryos (64.0 and 45.0%, respectively) were higher than those for demi-embryos obtained from two-cell embryos (49.0 and 31.0%, P<0.05). The separated demi-embryos obtained from eight-cell embryos produced by IVM/IVF of oocytes collected by ovum pick-up (OPU) from elite cows and cultured in wells tended to have a higher pregnancy rate (78.9% vs. 57.1%) and similar monozygotic twinning rate (40.0% vs. 33.3%) compared with monozygotic twin blastocysts obtained by the conventional bisection of in vivo derived blastocysts. In conclusion, producing twins by separation of blastomeres in OPU-IVF embryos, followed by the WOW culture system, yielded viable monozygotic demi-embryos, resulting in high rates of pregnancy and twinning rates after embryo transfer.

Food additives.

PubMed

Berglund, F

1978-01-01

The use of additives to food fulfils many purposes, as shown by the index issued by the Codex Committee on Food Additives: Acids, bases and salts; Preservatives, Antioxidants and antioxidant synergists; Anticaking agents; Colours; Emulfifiers; Thickening agents; Flour-treatment agents; Extraction solvents; Carrier solvents; Flavours (synthetic); Flavour enhancers; Non-nutritive sweeteners; Processing aids; Enzyme preparations. Many additives occur naturally in foods, but this does not exclude toxicity at higher levels. Some food additives are nutrients, or even essential nutritents, e.g. NaCl. Examples are known of food additives causing toxicity in man even when used according to regulations, e.g. cobalt in beer. In other instances, poisoning has been due to carry-over, e.g. by nitrate in cheese whey - when used for artificial feed for infants. Poisonings also occur as the result of the permitted substance being added at too high levels, by accident or carelessness, e.g. nitrite in fish. Finally, there are examples of hypersensitivity to food additives, e.g. to tartrazine and other food colours. The toxicological evaluation, based on animal feeding studies, may be complicated by impurities, e.g. orthotoluene-sulfonamide in saccharin; by transformation or disappearance of the additive in food processing in storage, e.g. bisulfite in raisins; by reaction products with food constituents, e.g. formation of ethylurethane from diethyl pyrocarbonate; by metabolic transformation products, e.g. formation in the gut of cyclohexylamine from cyclamate. Metabolic end products may differ in experimental animals and in man: guanylic acid and inosinic acid are metabolized to allantoin in the rat but to uric acid in man. The magnitude of the safety margin in man of the Acceptable Daily Intake (ADI) is not identical to the "safety factor" used when calculating the ADI. The symptoms of Chinese Restaurant Syndrome, although not hazardous, furthermore illustrate that the whole ADI

SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scott Reeves

2003-03-01

Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) The search for another field site was abandoned after discussion with DOE. There is a clear absence of willing industry partners to participate in this project. The greatest obstacle is having the necessary data to perform

Novel active driven drop tower facility for microgravity experiments investigating production technologies on the example of substrate-free additive manufacturing

NASA Astrophysics Data System (ADS)

Lotz, Christoph; Wessarges, Yvonne; Hermsdorf, Jörg; Ertmer, Wolfgang; Overmeyer, Ludger

2018-04-01

Through the striving of humanity into space, new production processes and technologies for the use under microgravity will be essential in the future. Production of objects in space demands for new processes, like additive manufacturing. This paper presents the concept and the realization for a new machine to investigate microgravity production processes on earth. The machine is based on linear long stator drives and a vacuum chamber carrying up to 1000 kg. For the first time high repetition rate and associated low experimental costs can provide basic research. The paper also introduces the substrate-free additive manufacturing as a future research topic and one of our primary application.

Phosphazene additives

DOEpatents

Harrup, Mason K; Rollins, Harry W

2013-11-26

An additive comprising a phosphazene compound that has at least two reactive functional groups and at least one capping functional group bonded to phosphorus atoms of the phosphazene compound. One of the at least two reactive functional groups is configured to react with cellulose and the other of the at least two reactive functional groups is configured to react with a resin, such as an amine resin of a polycarboxylic acid resin. The at least one capping functional group is selected from the group consisting of a short chain ether group, an alkoxy group, or an aryloxy group. Also disclosed are an additive-resin admixture, a method of treating a wood product, and a wood product.

Adverse reactions to the sulphite additives

PubMed Central

Misso, Neil LA

2012-01-01

Sulphites are widely used as preservative and antioxidant additives in the food and pharmaceutical industries. Exposure to sulphites has been reported to induce a range of adverse clinical effects in sensitive individuals, ranging from dermatitis, urticaria, flushing, hypotension, abdominal pain and diarrhoea to life-threatening anaphylactic and asthmatic reactions. Exposure to the sulphites arises mainly from the consumption of foods and drinks that contain these additives; however exposure may also occur through the use of pharmaceutical products, as well as in occupational settings. Most studies report a prevalence of sulphite sensitivity of 3 to 10% among asthmatic subjects who ingest these additives. However, the severity of these reactions varies, and steroid-dependent asthmatics, those with marked airway hyperresponsiveness, and children with chronic asthma, appear to be at greater risk. Although a number of potential mechanisms have been proposed, the precise mechanisms underlying sulphite sensitivity remain unclear. PMID:24834193

Molecular characterization of an unauthorized genetically modified Bacillus subtilis production strain identified in a vitamin B2 feed additive.

PubMed

Paracchini, Valentina; Petrillo, Mauro; Reiting, Ralf; Angers-Loustau, Alexandre; Wahler, Daniela; Stolz, Andrea; Schönig, Birgit; Matthies, Anastasia; Bendiek, Joachim; Meinel, Dominik M; Pecoraro, Sven; Busch, Ulrich; Patak, Alex; Kreysa, Joachim; Grohmann, Lutz

2017-09-01

Many food and feed additives result from fermentation of genetically modified (GM) microorganisms. For vitamin B2 (riboflavin), GM Bacillus subtilis production strains have been developed and are often used. The presence of neither the GM strain nor its recombinant DNA is allowed for fermentation products placed on the EU market as food or feed additive. A vitamin B 2 product (80% feed grade) imported from China was analysed. Viable B. subtilis cells were identified and DNAs of two bacterial isolates (LHL and LGL) were subjected to three whole genome sequencing (WGS) runs with different devices (MiSeq, 454 or HiSeq system). WGS data revealed the integration of a chloramphenicol resistance gene, the deletion of the endogenous riboflavin (rib) operon and presence of four putative plasmids harbouring rib operons. Event- and construct-specific real-time PCR methods for detection of the GM strain and its putative plasmids in food and feed products have been developed. Copyright © 2017 Elsevier Ltd. All rights reserved.

Effect of Steam Deactivation Severity of ZSM-5 Additives on LPG Olefins Production in the FCC Process.

PubMed

Gusev, Andrey A; Psarras, Antonios C; Triantafyllidis, Konstantinos S; Lappas, Angelos A; Diddams, Paul A

2017-10-21

ZSM-5-containing catalytic additives are widely used in oil refineries to boost light olefin production and improve gasoline octanes in the Fluid Catalytic Cracking (FCC) process. Under the hydrothermal conditions present in the FCC regenerator (typically >700 °C and >8% steam), FCC catalysts and additives are subject to deactivation. Zeolites (e.g., Rare Earth USY in the base catalyst and ZSM-5 in Olefins boosting additives) are prone to dealumination and partial structural collapse, thereby losing activity, micropore surface area, and undergoing changes in selectivity. Fresh catalyst and additives are added at appropriate respective levels to the FCC unit on a daily basis to maintain overall targeted steady-state (equilibrated) activity and selectivity. To mimic this process under accelerated laboratory conditions, a commercial P/ZSM-5 additive was hydrothermally equilibrated via a steaming process at two temperatures: 788 °C and 815 °C to simulate moderate and more severe equilibration industrial conditions, respectively. n -Dodecane was used as probe molecule and feed for micro-activity cracking testing at 560 °C to determine the activity and product selectivity of fresh and equilibrated P-doped ZSM-5 additives. The fresh/calcined P/ZSM-5 additive was very active in C 12 cracking while steaming limited its activity, i.e., at catalyst-to-feed (C/F) ratio of 1, about 70% and 30% conversion was obtained with the fresh and steamed additives, respectively. A greater activity drop was observed upon increasing the hydrothermal deactivation severity due to gradual decrease of total acidity and microporosity of the additives. However, this change in severity did not result in any selectivity changes for the LPG (liquefied petroleum gas) olefins as the nature (Brønsted-to-Lewis ratio) of the acid/active sites was not significantly altered upon steaming. Steam deactivation of ZSM-5 had also no significant effect on aromatics formation which was enhanced at higher

SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scott Reeves

2003-03-01

Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Continued to solicit industry research partners to provide test sites, including Patina Oil and Gas and EOG Resources, each of whom have previously worked with ARI on a similar projects funded by the Gas Technology

Effect of catalyst additives on the production of biofuels from palm oil cracking in a transport riser reactor.

PubMed

Chew, Thiam Leng; Bhatia, Subhash

2009-05-01

Catalytic cracking of crude palm oil (CPO) and used palm oil (UPO) were studied in a transport riser reactor for the production of biofuels at a reaction temperature of 450 degrees C, with residence time of 20s and catalyst-to-oil ratio (CTO) of 5 gg(-1). The effect of HZSM-5 (different Si/Al ratios), beta zeolite, SBA-15 and AlSBA-15 were studied as physically mixed additives with cracking catalyst Rare earth-Y (REY). REY catalyst alone gave 75.8 wt% conversion with 34.5 wt% of gasoline fraction yield using CPO, whereas with UPO, the conversion was 70.9 wt% with gasoline fraction yield of 33.0 wt%. HZSM-5, beta zeolite, SBA-15 and AlSBA-15 as additives with REY increased the conversion and the yield of organic liquid product. The transport riser reactor can be used for the continuous production of biofuels from cracking of CPO and UPO over REY catalyst.

Overall well-being as a predictor of health care, productivity, and retention outcomes in a large employer.

PubMed

Sears, Lindsay E; Shi, Yuyan; Coberley, Carter R; Pope, James E

2013-12-01

Employers struggle with the high cost of health care, lost productivity, and turnover in their workforce. The present study aims to understand the association between overall well-being and these employer outcomes. In a sample of 11,700 employees who took the Well-being Assessment, the authors used multivariate linear and logistic regression to investigate overall well-being as a predictor of health care outcomes (total health care expenditure, emergency room visits, hospitalizations), productivity outcomes (unscheduled absence, short-term disability leave, presenteeism, job performance ratings), and retention outcomes (intention to stay, voluntary turnover, involuntary turnover). Testing this hypothesis both cross-sectionally and longitudinally, the authors investigated the association between baseline well-being and these outcomes in the following year, and the relationship between change in overall well-being and change in these outcomes over 1 year. The results demonstrated that baseline overall well-being was a significant predictor of all outcomes in the following year when holding baseline employee characteristics constant. Change in overall well-being over 1 year also was significantly associated with the change in employer outcomes, with the exception that the relationship to change in manager-rated job performance was marginally significant. The relationships between overall well-being and outcomes suggest that implementing a well-being improvement solution could have a significant bottom and top line impact on business performance.

DNA-Catalyzed DNA Cleavage by a Radical Pathway with Well-Defined Products.

PubMed

Lee, Yujeong; Klauser, Paul C; Brandsen, Benjamin M; Zhou, Cong; Li, Xinyi; Silverman, Scott K

2017-01-11

We describe an unprecedented DNA-catalyzed DNA cleavage process in which a radical-based reaction pathway cleanly results in excision of most atoms of a specific guanosine nucleoside. Two new deoxyribozymes (DNA enzymes) were identified by in vitro selection from N 40 or N 100 random pools initially seeking amide bond hydrolysis, although they both cleave simple single-stranded DNA oligonucleotides. Each deoxyribozyme generates both superoxide (O 2 -• or HOO • ) and hydrogen peroxide (H 2 O 2 ) and leads to the same set of products (3'-phosphoglycolate, 5'-phosphate, and base propenal) as formed by the natural product bleomycin, with product assignments by mass spectrometry and colorimetric assay. We infer the same mechanistic pathway, involving formation of the C4' radical of the guanosine nucleoside that is subsequently excised. Consistent with a radical pathway, glutathione fully suppresses catalysis. Conversely, adding either superoxide or H 2 O 2 from the outset strongly enhances catalysis. The mechanism of generation and involvement of superoxide and H 2 O 2 by the deoxyribozymes is not yet defined. The deoxyribozymes do not require redox-active metal ions and function with a combination of Zn 2+ and Mg 2+ , although including Mn 2+ increases the activity, and Mn 2+ alone also supports catalysis. In contrast to all of these observations, unrelated DNA-catalyzed radical DNA cleavage reactions require redox-active metals and lead to mixtures of products. This study reports an intriguing example of a well-defined, DNA-catalyzed, radical reaction process that cleaves single-stranded DNA and requires only redox-inactive metal ions.

Insight into the Genome of Staphylococcus xylosus, a Ubiquitous Species Well Adapted to Meat Products

PubMed Central

Leroy, Sabine; Vermassen, Aurore; Ras, Geoffrey; Talon, Régine

2017-01-01

Staphylococcus xylosus belongs to the vast group of coagulase-negative staphylococci. It is frequently isolated from meat products, either fermented or salted and dried, and is commonly used as starter cultures in sausage manufacturing. Analysis of the S. xylosus genome together with expression in situ in a meat model revealed that this bacterium is well adapted to meat substrates, being able to use diverse substrates as sources of carbon and energy and different sources of nitrogen. It is well-equipped with genes involved in osmotic, oxidative/nitrosative, and acidic stress responses. It is responsible for the development of the typical colour of cured meat products via its nitrate reductase activity. It contributes to sensorial properties, mainly by the the catabolism of pyruvate and amino acids resulting in odorous compounds and by the limiting of the oxidation of fatty acids, thereby avoiding rancidity. PMID:28850086

Altering Reservoir Wettability to Improve Production from Single Wells

DOE Office of Scientific and Technical Information (OSTI.GOV)

W. W. Weiss

2006-09-30

field tests were conducted in an area of the field that has not met production expectations. The dataset on the 23 Phosphoria well surfactant soaks was updated. An analysis of the oil decline curves indicted that 4.5 lb of chemical produced a barrel of incremental oil. The AI analysis supports the adage 'good wells are the best candidates.' The generally better performance of surfactant in the high permeability core laboratory tests supports this observation. AI correlations were developed to predict the response to water-frac stimulations in a tight San Andres reservoir. The correlations maybe useful in the design of Cedar Creek Anticline surfactant soak treatments planned for next year. Nuclear Magnetic Resonance scans of dolomite cores to measure porosity and saturation during the high temperature laboratory work were acquired. The scans could not be correlated with physical measurement using either conventional or AI methods.« less

Solid sand particle addition can enhance the production of resting cysts in dinoflagellates

NASA Astrophysics Data System (ADS)

Yang, Aoao; Hu, Zhangxi; Tang, Yingzhong

2018-03-01

Resting cysts are an important part of the life cycle for many harmful algal bloom-forming dinoflagellates, and play vital roles in the recurrence and geographical spread of harmful algal blooms. Numerous factors have been suggested to regulate the formation of resting cysts, although only a few have been proven to be significant. Cyst formation can be induced by adverse environmental conditions such as drastic changes in temperature, light, salinity, and nutrient levels, and by biological interactions. In this study, we evaluated the ability of an artificial factor (fine sand particles) to enhance the formation of resting cysts. Fine sand particles were added to cultures of dinoflagellates that are known to produce cysts. The addition of fine sand particles significantly increased both the production rate and final yield of cysts in cultures of Scrippsiella trochoidea, Biecheleria brevisulcata, and Levanderina fissa (= Gymnodinium fissum, Gyrodinium instriatum, Gyrodinium uncatenum). The largest increase in the final yield (107-fold) of cysts as a result of sand addition was in S. trochoidea. However, addition of fine sand particles did not induce cyst formation, or barely affected cyst formation, in Akashiwo sanguinea, Cochlodinium polykrikoides and Pheopolykrikos hartmannii, which are also known to be cyst-producing species. We speculated that addition of sand significantly increased the chances of cell collision, which triggered cyst formation. However, further research is required to test this idea. Importantly, our findings indicate that the addition of fine sand particles is a useful method to obtain a large quantity of cysts in a short time for laboratory studies or tests; for example, if a cyst viability test is being used to assess the effectiveness of ships' ballast water treatment.

GAS INJECTION/WELL STIMULATION PROJECT

DOE Office of Scientific and Technical Information (OSTI.GOV)

John K. Godwin

2005-12-01

Driver Production proposes to conduct a gas repressurization/well stimulation project on a six well, 80-acre portion of the Dutcher Sand of the East Edna Field, Okmulgee County, Oklahoma. The site has been location of previous successful flue gas injection demonstration but due to changing economic and sales conditions, finds new opportunities to use associated natural gas that is currently being vented to the atmosphere to repressurize the reservoir to produce additional oil. The established infrastructure and known geological conditions should allow quick startup and much lower operating costs than flue gas. Lessons learned from the previous project, the lessons learnedmore » form cyclical oil prices and from other operators in the area will be applied. Technology transfer of the lessons learned from both projects could be applied by other small independent operators.« less

Alcorn wells bolster Philippines oil production

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-09-21

This paper reports that Alcorn International Inc., Houston, is producing about 16,500 b/d of oil from West Linapacan A field in the South China Sea off the Philippines. The field's current production alone is more than fivefold the Philippines' total average oil flow of 3,000 b/d in 1991. It's part of a string of oil and gas strikes off Palawan Island that has made the region one of the hottest exploration/development plays in the Asia-Pacific theater.

Palliative care is not yet a well-defined product within the Dutch healthcare insurance system.

PubMed

Jansen, Wim J J; Vissers, Kris C P; Zuurmond, Wouter W A; van Montfort, Guus P W P; Rhebergen, Andre; Loer, Stephan A

2009-07-01

In the Netherlands, the quality and availability of palliative care has improved markedly within the last decade. However, many open questions remain concerning the position of palliative care as an insurable product on the Dutch healthcare market. Therefore, we analysed the policies of all private Dutch healthcare insurance companies as well as the public insurance policy for extraordinary medical costs. We studied how and which parts of palliative care were reimbursed in 2007. We observed a huge variability in costs and reimbursement regulations reflecting a rapid turnover of products for palliative care due to various new developments on this specific field of medical care. We conclude that a better definition of the product 'palliative care' is necessary for patients, health care providers and insurance companies.

The three-zone composite productivity model for a multi-fractured horizontal shale gas well

NASA Astrophysics Data System (ADS)

Qi, Qian; Zhu, Weiyao

2018-02-01

Due to the nano-micro pore structures and the massive multi-stage multi-cluster hydraulic fracturing in shale gas reservoirs, the multi-scale seepage flows are much more complicated than in most other conventional reservoirs, and are crucial for the economic development of shale gas. In this study, a new multi-scale non-linear flow model was established and simplified, based on different diffusion and slip correction coefficients. Due to the fact that different flow laws existed between the fracture network and matrix zone, a three-zone composite model was proposed. Then, according to the conformal transformation combined with the law of equivalent percolation resistance, the productivity equation of a horizontal fractured well, with consideration given to diffusion, slip, desorption, and absorption, was built. Also, an analytic solution was derived, and the interference of the multi-cluster fractures was analyzed. The results indicated that the diffusion of the shale gas was mainly in the transition and Fick diffusion regions. The matrix permeability was found to be influenced by slippage and diffusion, which was determined by the pore pressure and diameter according to the Knudsen number. It was determined that, with the increased half-lengths of the fracture clusters, flow conductivity of the fractures, and permeability of the fracture network, the productivity of the fractured well also increased. Meanwhile, with the increased number of fractures, the distance between the fractures decreased, and the productivity slowly increased due to the mutual interfere of the fractures.

Coupling Hydraulic Fracturing Propagation and Gas Well Performance for Simulation of Production in Unconventional Shale Gas Reservoirs

NASA Astrophysics Data System (ADS)

Wang, C.; Winterfeld, P. H.; Wu, Y. S.; Wang, Y.; Chen, D.; Yin, C.; Pan, Z.

2014-12-01

Hydraulic fracturing combined with horizontal drilling has made it possible to economically produce natural gas from unconventional shale gas reservoirs. An efficient methodology for evaluating hydraulic fracturing operation parameters, such as fluid and proppant properties, injection rates, and wellhead pressure, is essential for the evaluation and efficient design of these processes. Traditional numerical evaluation and optimization approaches are usually based on simulated fracture properties such as the fracture area. In our opinion, a methodology based on simulated production data is better, because production is the goal of hydraulic fracturing and we can calibrate this approach with production data that is already known. This numerical methodology requires a fully-coupled hydraulic fracture propagation and multi-phase flow model. In this paper, we present a general fully-coupled numerical framework to simulate hydraulic fracturing and post-fracture gas well performance. This three-dimensional, multi-phase simulator focuses on: (1) fracture width increase and fracture propagation that occurs as slurry is injected into the fracture, (2) erosion caused by fracture fluids and leakoff, (3) proppant subsidence and flowback, and (4) multi-phase fluid flow through various-scaled anisotropic natural and man-made fractures. Mathematical and numerical details on how to fully couple the fracture propagation and fluid flow parts are discussed. Hydraulic fracturing and production operation parameters, and properties of the reservoir, fluids, and proppants, are taken into account. The well may be horizontal, vertical, or deviated, as well as open-hole or cemented. The simulator is verified based on benchmarks from the literature and we show its application by simulating fracture network (hydraulic and natural fractures) propagation and production data history matching of a field in China. We also conduct a series of real-data modeling studies with different combinations of

Changes in in vitro gas and methane production from rumen fluid from dairy cows during adaptation to feed additives in vivo.

PubMed

Klop, G; van Laar-van Schuppen, S; Pellikaan, W F; Hendriks, W H; Bannink, A; Dijkstra, J

2017-04-01

The adaptation of dairy cows to methane (CH4)-mitigating feed additives was evaluated using the in vitro gas production (GP) technique. Nine rumen-fistulated lactating Holstein cows were grouped into three blocks and within blocks randomly assigned to one of three experimental diets: Control (CON; no feed additive), Agolin Ruminant® (AR; 0.05 g/kg dry matter (DM)) or lauric acid (LA; 30 g/kg DM). Total mixed rations composed of maize silage, grass silage and concentrate were fed in a 40 : 30 : 30 ratio on DM basis. Rumen fluid was collected from each cow at days -4, 1, 4, 8, 15 and 22 relative to the introduction of the additives in the diets. On each of these days, a 48-h GP experiment was performed in which rumen fluid from each individual donor cow was incubated with each of the three substrates that reflected the treatment diets offered to the cows. DM intake was on average 19.8, 20.1 and 16.2 kg/day with an average fat- and protein-corrected milk production of 30.7, 31.7 and 26.2 kg/day with diet CON, AR and LA, respectively. In general, feed additives in the donor cow diet had a larger effect on gas and CH4 production than the same additives in the incubation substrate. Incubation substrate affected asymptotic GP, half-time of asymptotic CH4 production, total volatile fatty acid (VFA) concentration, molar proportions of propionate and butyrate and degradation of organic matter (OMD), but did not affect CH4 production. No substrate×day interactions were observed. A significant diet×day interaction was observed for in vitro gas and CH4 production, total VFA concentration, molar proportions of VFA and OMD. From day 4 onwards, the LA diet persistently reduced gas and CH4 production, total VFA concentration, acetate molar proportion and OMD, and increased propionate molar proportion. In vitro CH4 production was reduced by the AR diet on day 8, but not on days 15 and 22. In line with these findings, the molar proportion of propionate in fermentation fluid was

Inhibitory effects of food additives derived from polyphenols on staphylococcal enterotoxin A production and biofilm formation by Staphylococcus aureus.

PubMed

Shimamura, Yuko; Hirai, Chikako; Sugiyama, Yuka; Shibata, Masaharu; Ozaki, Junya; Murata, Masatsune; Ohashi, Norio; Masuda, Shuichi

2017-12-01

In this study, we examined the inhibitory effects of 14 food additives derived from polyphenol samples on staphylococcal enterotoxin A (SEA) production and biofilm formation by Staphylococcus aureus. Tannic acid AL (TA), Purephenon 50 W (PP) and Polyphenon 70A (POP) at 0.25 mg/mL and Gravinol®-N (GN), Blackcurrant polyphenol AC10 (BP), and Resveratrol-P5 (RT) at 1.0 mg/mL significantly decreased SEA production by S. aureus C-29 (p < 0.05). TA, GN, BP, and RT significantly inhibited the expression of the sea gene in S. aureus C-29 (p < 0.05), while suppression attempts by PP and POP proved unsuccessful. After result analysis, it can be derived that TA, GN, BP, and RT inhibit the production of SEA. Of the six samples, each one significantly inhibited biofilm formation (p < 0.05). Food additives derived from polyphenols have viability to be used as a means to inhibit the enterotoxin production and control the biofilm formation of foodborne pathogens.

Overall Well-Being as a Predictor of Health Care, Productivity, and Retention Outcomes in a Large Employer

PubMed Central

Shi, Yuyan; Coberley, Carter R.; Pope, James E.

2013-01-01

Abstract Employers struggle with the high cost of health care, lost productivity, and turnover in their workforce. The present study aims to understand the association between overall well-being and these employer outcomes. In a sample of 11,700 employees who took the Well-being Assessment, the authors used multivariate linear and logistic regression to investigate overall well-being as a predictor of health care outcomes (total health care expenditure, emergency room visits, hospitalizations), productivity outcomes (unscheduled absence, short-term disability leave, presenteeism, job performance ratings), and retention outcomes (intention to stay, voluntary turnover, involuntary turnover). Testing this hypothesis both cross-sectionally and longitudinally, the authors investigated the association between baseline well-being and these outcomes in the following year, and the relationship between change in overall well-being and change in these outcomes over 1 year. The results demonstrated that baseline overall well-being was a significant predictor of all outcomes in the following year when holding baseline employee characteristics constant. Change in overall well-being over 1 year also was significantly associated with the change in employer outcomes, with the exception that the relationship to change in manager-rated job performance was marginally significant. The relationships between overall well-being and outcomes suggest that implementing a well-being improvement solution could have a significant bottom and top line impact on business performance. (Population Health Management 2013;16:397–405) PMID:23480368

Teachers' Misconceptions about the Effects of Addition of More Reactants or Products on Chemical Equilibrium

ERIC Educational Resources Information Center

Cheung, Derek; Ma, Hong-jia; Yang, Jie

2009-01-01

The importance of research on misconceptions about chemical equilibrium is well recognized by educators, but in the past, researchers' interest has centered on student misconceptions and has neglected teacher misconceptions. Focusing on the effects of adding more reactants or products on chemical equilibrium, this article discusses the various…

The Impact of Additives on the Phosphorus, Potassium, and Sodium Content of Commonly Consumed Meat, Poultry, and Fish Products Among Patients With Chronic Kidney Disease.

PubMed

Parpia, Arti Sharma; L'Abbé, Mary; Goldstein, Marc; Arcand, Joanne; Magnuson, Bernadene; Darling, Pauline B

2018-03-01

Patients with chronic kidney disease (CKD) are advised to limit their dietary intake of phosphorus and potassium as hyperphosphatemia and hyperkalemia are both associated with an increased risk of mortality. There is uncertainty concerning the actual content of these minerals in the Canadian food supply, as phosphorus and potassium are increasingly being used as food additives. This study aimed to determine the impact of food additives on the chemically analyzed content of phosphorus, potassium, sodium, and protein in commonly consumed meat, poultry, and fish products (MPFs). Foods representing commonly consumed MPF identified by a food frequency questionnaire in dialysis patients were purchased from three major grocery store chains in Canada. MPF with and without phosphorus and potassium additives listed on their ingredient list (n = 76) as well as reference MPF that was additive free (n = 15) were chemically analyzed for phosphorus, potassium, sodium, and protein content according to Association of Analytical Community official methods. Phosphorus, potassium, and sodium additives were present on the ingredient list in 37%, 9%, and 72% of MPF, respectively. Among MPF categories that contained a phosphorus additive, phosphorus content was significantly (P < .05) higher in MPF with phosphorus additives versus MPF without phosphorus additives and MPF reference foods (median [min, max]): (270 [140, 500] mg/100 g) versus (200 [130, 510] mg/100 g) versus (210 [100, 260] mg/100 g), respectively. Among MPF categories containing a potassium additive, foods listing a potassium additive had significantly more (P < .05) potassium than foods that did not list potassium additives and reference foods (900 [750, 1100] mg/100 g) versus (325 [260, 470] mg/100 g) versus (420 [270, 450] mg/100 g). The use of additives in packaged MPF products as indicated by the ingredient list can significantly contribute to the dietary phosphorus and potassium loads in patients with

Guanosine 5′-monophosphate-chelated calcium and iron feed additives maintains egg production and prevents Salmonella Gallinarum in experimentally infected layers

PubMed Central

Noh, Hye-Ji; Kim, HeeKyong; Heo, Su Jeong; Cho, Hyang Hyun

2017-01-01

We evaluated the effects of guanosine 5′-monophosphate (GMP)-chelated calcium and iron (CaFe-GMP) on health and egg quality in layers experimentally infected with Salmonella Gallinarum. In this study, a CaFe-GMP feed additive was added to a commercial layer feed and fed to layers over a four-week period. All were inoculated with Salmonella Gallinarum. Body weight, mortality, clinical symptoms, and poultry production including feed intake, egg production, egg loss, and feed conversion rate were observed, and Salmonella Gallinarum was re-isolated from the liver, spleen, and cecum of the layers. All tested internal organs for the CaFe-GMP additive group exhibited significantly lower re-isolation numbers of Salmonella Gallinarum and less severe pathological changes than those in the control group, indicating that the CaFe-GMP feed supplement induced bacterial clearance and increased resistance to Salmonella Gallinarum. Additionally, due to the inhibitory action of CaFe-GMP on the growth of Salmonella Gallinarum, the CaFe-GMP additive group exhibited better egg production, including a higher laying rate and fewer broken eggs. The results suggest that a 0.16% CaFe-GMP additive may help prevent salmonellosis in the poultry industry. PMID:28057911

Search for additional muons in hadronic production of Jψ particles

NASA Astrophysics Data System (ADS)

Anderson, K. J.; Coleman, R. N.; Karhi, K. P.; Newman, C. B.; Pilcher, J. E.; Rosenberg, E. I.; Thaler, J. J.; Hogan, G. E.; McDonald, K. T.; Sanders, G. H.; Smith, A. J. S.

1980-06-01

A sample of Jψ-->μ+μ- decays produced by a 225-GeV/c π- beam on nuclear targets has been analyzed for extra muons. Muons observed in coincidence with Jψ production could indicate either the production of charmed particles or the production of pairs of Jψ particles. We find 90% confidence limits of σ-JDDσJ<0.016 for associated charm production and σJJσJ<0.005 for the production of Jψ pairs.

Tracking The Changing Landscape Of Corporate Wellness Companies.

PubMed

Abraham, Jean; White, Katie M

2017-02-01

The corporate wellness industry is diversifying and now includes legacy wellness companies, divisions of health plans or delivery systems, and new technology-focused solution enterprises. We conducted in-depth interviews with leaders in the industry to understand the changes in its supply side, the drivers of these changes, future trends, and their implications for employers and policy makers. Three key trends emerged from the interviews: The industry is expanding and becoming increasingly diverse and competitive; wellness companies are redefining their business models to promote a culture of health; and the value proposition of employee wellness programs is shifting from a return on investment to a new idea: value on investment. Our findings clarify wellness companies' innovations, their contributions to population health improvement efforts, and the need for additional evidence to demonstrate the value of the new generation of wellness products and services. Project HOPE—The People-to-People Health Foundation, Inc.

Studies on some feed additives and materials giving partial protection against the suppressive effect of ochratoxin A on egg production of laying hens.

PubMed

Stoev, Stoycho D

2010-06-01

The protective effects of various feed supplements against the harmful effect of ochratoxin A on egg production and sexual maturation of two-weeks old Plymouth Rock female chicks designed for laying hens were studied. A significant protective effect of the feed additives or materials: water extract of artichoke (WEA), sesame seed (SS), Roxazyme-G (RG) and l-beta phenylalanine (PHE) against the suppressive effect of ochratoxin A (OTA) on egg production of laying hens was found. A similar protection was also seen on the toxic effect of OTA on various internal organs of the same hens. A significant protection was found against the decrease of the weight or the quantity of eggs as well as against the delay of the beginning of the laying period of chicks, both of which were provoked by ochratoxin A. These protective effects were strongest in chicks treated with SS or WEA, but were slightest in chicks treated with l-beta PHE. Copyright 2009 Elsevier Ltd. All rights reserved.

Use of soybean oil and ammonium sulfate additions to optimize secondary metabolite production.

PubMed

Junker, B; Mann, Z; Gailliot, P; Byrne, K; Wilson, J

1998-12-05

A valine-overproducing mutant (MA7040, Streptomyces hygroscopicus) was found to produce 1.5 to 2.0 g/L of the immunoregulant, L-683,590, at the 0.6 m3 fermentation scale in a simple batch process using soybean oil and ammonium sulfate-based GYG5 medium. Levels of both lower (L-683,795) and higher (HH1 and HH2) undesirable homolog levels were controlled adequately. This batch process was utilized to produce broth economically at the 19 m3 fermentation scale. Material of acceptable purity was obtained without the multiple pure crystallizations previously required for an earlier culture, MA6678, requiring valine supplementation for impurity control. Investigations at the 0.6 m3 fermentation scale were conducted, varying agitation, pH, initial soybean oil/ammonium sulfate charges, and initial aeration rate to further improve growth and productivity. Mid-cycle ammonia levels and lipase activity appeared to have an important role. Using mid-cycle soybean oil additions, a titer of 2.3 g/L of L-683,590 was obtained, while titers reached 2.7 g/L using mid-cycle soybean oil and ammonium sulfate additions. Both higher and lower homolog levels remained acceptable during this fed-batch process. Optimal timing of mid-cycle oil and ammonium sulfate additions was considered a critical factor to further titer improvements. Copyright 1998 John Wiley & Sons, Inc.

Volatile organic compounds at two oil and natural gas production well pads in Colorado and Texas using passive samplers.

PubMed

Eisele, Adam P; Mukerjee, Shaibal; Smith, Luther A; Thoma, Eben D; Whitaker, Donald A; Oliver, Karen D; Wu, Tai; Colon, Maribel; Alston, Lillian; Cousett, Tamira A; Miller, Michael C; Smith, Donald M; Stallings, Casson

2016-04-01

A pilot study was conducted in application of the U.S. Environmental Protection Agency (EPA) Methods 325A/B variant for monitoring volatile organic compounds (VOCs) near two oil and natural gas (ONG) production well pads in the Texas Barnett Shale formation and Colorado Denver-Julesburg Basin (DJB), along with a traffic-dominated site in downtown Denver, CO. As indicated in the EPA method, VOC concentrations were measured for 14-day sampling periods using passive-diffusive tube samplers with Carbopack X sorbent at fenceline perimeter and other locations. VOCs were significantly higher at the DJB well pad versus the Barnett well pad and were likely due to higher production levels at the DJB well pad during the study. Benzene and toluene were significantly higher at the DJB well pad versus downtown Denver. Except for perchloroethylene, VOCs measured at passive sampler locations (PSs) along the perimeter of the Barnett well pad were significantly higher than PSs farther away. At the DJB well pad, most VOC concentrations, except perchloroethylene, were significantly higher prior to operational changes than after these changes were made. Though limited, the results suggest passive samplers are precise (duplicate precision usually ≤10%) and that they can be useful to assess spatial gradients and operational conditions at well pad locations over time-integrated periods. Recently enacted EPA Methods 325A/B use passive-diffusive tube samplers to measure benzene at multiple fenceline locations at petrochemical refineries. This pilot study presents initial data demonstrating the utility of Methods 325A/B for monitoring at ONG facilities. Measurements revealed elevated concentrations reflective of production levels and spatial gradients of VOCs relative to source proximity at the Barnett well pad, as well as operational changes at the DJB well pad. Though limited, these findings indicate that Methods 325A/B can be useful in application to characterize VOCs at well pad

Productivity and growth performance of edamame (Glycin Max L Merril) due to the addition of sitokinin

NASA Astrophysics Data System (ADS)

Rohmawati, Irma; Ulfah, Maria

2018-05-01

Global market demand towards edamame is quite high, but production of edamame is still very low. Edamame have to increased its production. Many researchers stated that sitokinin effect on the activities of enzymes in metabolic processes of plants. This research aims to analyze response of plant physiological Edamame applied with hormones sitokinin especially in aspects of growth and productivity. The research was carried out in March-May 2017. This study used a Randomized Complete Design method with three treatment factors that is A (unannounced sitokinin hormone), B (hormone siokinin 0.5 mL) C (hormone sitokinin 1 mL) with 5 repetitions. The parameters observed were higher plants, number of leaves, and the weight of the fruit. Research shows that treatment with hormone sitokinin effect on the growth and the production of edamame. The addition of the sitokinin hormones can increase the growth of leaves, stems, and fruit productivity. Results of the study showed treatment C (sitokinin 1 mL) gives signifcant effect. At the age of 48 HST by administering hormones 1 mL, has an average height of 28.8 cm, average number of leaves 15, and heavy weight fruit 17.43 grams.

Holistic Design for Total Product Well Being

NASA Technical Reports Server (NTRS)

Adams, Chris W.; Hamilton, George S.

2004-01-01

Recent hardware development work at NASA's Marshall Space Flight Center creates and argument for the use of a holistic design approach as opposed to a piece part design approach. A piece part design approach being one where individual pieces are developed to their finished state having to meet certain interface and human engineering requirements without much consideration to the final product as a whole. A holistic design approach being one where the final product is evaluated early and frequently during the design process, and individual parts are developed with consideration to how they interact a whole,and how they interact with the user and environment. Examples from the development of the Materials Science Research Rack - 1 will illustrate: a design failure due to piece part design; a design save, due to a failure of piece part design, but saved by evaluating the design holistically; and a design success due to a holistic design approach.

Additive manufacturing of materials: Opportunities and challenges

DOE Office of Scientific and Technical Information (OSTI.GOV)

Babu, Sudarsanam Suresh; Love, Lonnie J.; Dehoff, Ryan R.

Additive manufacturing (also known as 3D printing) is considered a disruptive technology for producing components with topologically optimized complex geometries as well as functionalities that are not achievable by traditional methods. The realization of the full potential of 3D printing is stifled by a lack of computational design tools, generic material feedstocks, techniques for monitoring thermomechanical processes under in situ conditions, and especially methods for minimizing anisotropic static and dynamic properties brought about by microstructural heterogeneity. In this paper, we discuss the role of interdisciplinary research involving robotics and automation, process control, multiscale characterization of microstructure and properties, and high-performancemore » computational tools to address each of these challenges. In addition, emerging pathways to scale up additive manufacturing of structural materials to large sizes (>1 m) and higher productivities (5–20 kg/h) while maintaining mechanical performance and geometrical flexibility are also discussed.« less

Additive manufacturing of materials: Opportunities and challenges

DOE PAGES

Babu, Sudarsanam Suresh; Love, Lonnie J.; Dehoff, Ryan R.; ...

2015-11-01

Additive manufacturing (also known as 3D printing) is considered a disruptive technology for producing components with topologically optimized complex geometries as well as functionalities that are not achievable by traditional methods. The realization of the full potential of 3D printing is stifled by a lack of computational design tools, generic material feedstocks, techniques for monitoring thermomechanical processes under in situ conditions, and especially methods for minimizing anisotropic static and dynamic properties brought about by microstructural heterogeneity. In this paper, we discuss the role of interdisciplinary research involving robotics and automation, process control, multiscale characterization of microstructure and properties, and high-performancemore » computational tools to address each of these challenges. In addition, emerging pathways to scale up additive manufacturing of structural materials to large sizes (>1 m) and higher productivities (5–20 kg/h) while maintaining mechanical performance and geometrical flexibility are also discussed.« less

Benchmarking Naval Shipbuilding With 3D Laser Scanning, Additive Manufacturing, and Collaborative Product Lifecycle Management

DTIC Science & Technology

2016-04-30

manufacturing is also commonly referred to as 3D printing . AM differs radically from the currently dominant manufacturing methodologies. Most current...referred to as 3D printing . In the automotive industry, Ford Motor Co. uses 3D printing in several areas, including the tooling used to create production...four months and cost $500,000 to build, while a 3D - printed manifold prototype costs $3,000 to build over four days. Additive Manufacturing in the

Analysis of additives in dairy products by liquid chromatography coupled to quadrupole-orbitrap mass spectrometry.

PubMed

Jia, Wei; Ling, Yun; Lin, Yuanhui; Chang, James; Chu, Xiaogang

2014-04-04

A new method combining QuEChERS with ultrahigh-performance liquid chromatography and electrospray ionization quadrupole Orbitrap high-resolution mass spectrometry (UHPLC/ESI Q-Orbitrap) was developed for the highly accurate and sensitive screening of 43 antioxidants, preservatives and synthetic sweeteners in dairy products. Response surface methodology was employed to optimize a quick, easy, cheap, effective, rugged, and safe (QuEChERS) sample preparation method for the determination of 42 different analytes in dairy products for the first time. After optimization, the maximum predicted recovery was 99.33% rate for aspartame under the optimized conditions of 10 mL acetionitrile, 1.52 g sodium acetate, 410 mg PSA and 404 mgC18. For the matrices studied, the recovery rates of the other 42 compounds ranged from 89.4% to 108.2%, with coefficient of variation <6.4%. UHPLC/ESI Q-Orbitrap Mass full scan mode acquired full MS data was used to identify and quantify additives, and data-dependent scan mode obtained fragment ion spectra for confirmation. The mass accuracy typically obtained is routinely better than 1.5ppm, and only need to calibrate once a week. The 43 compounds behave dynamic in the range 0.001-1000 μg kg(-1) concentration, with correlation coefficient >0.999. The limits of detection for the analytes are in the range 0.0001-3.6 μg kg(-1). This method has been successfully applied on screening of antioxidants, preservatives and synthetic sweeteners in commercial dairy product samples, and it is very useful for fast screening of different food additives. Copyright © 2014 Elsevier B.V. All rights reserved.

Production of cellobionate from cellulose using an engineered Neurospora crassa strain with laccase and redox mediator addition

USDA-ARS?s Scientific Manuscript database

We report a novel production process for cellobionic acid from cellulose using an engineered fungal strain with the exogenous addition of laccase and a redox mediator. A previously engineered strain of Neurospora crassa (F5'ace-1'cre-1'ndvB) was shown to produce cellobionate directly from cellulose ...

Characterizing contaminant concentrations with depth by using the USGS well profiler in Oklahoma, 2003-9

USGS Publications Warehouse

Smith, S. Jerrod; Becker, Carol J.

2011-01-01

In 2007, the USGS well profiler was used to investigate saline water intrusion in a deep public-supply well completed in the Ozark (Roubidoux) aquifer. In northeast Oklahoma, where the Ozark aquifer is known to be susceptible to contamination from mining activities, the well profiler also could be used to investigate sources (depths) of metals contamination and to identify routes of entry of metals to production wells.Water suppliers can consider well rehabilitation as a potential remediation strategy because of the ability to identify changes in contaminant concentrations with depth in individual wells with the USGS well profiler. Well rehabilitation methods, which are relatively inexpensive compared to drilling and completing new wells, involve modifying the construction or operation of a well to enhance the production of water from zones with lesser concentrations of a contaminant or to limit the production of water from zones with greater concentrations of a contaminant. One of the most effective well rehabilitation methods is zonal isolation, in which water from contaminated zones is excluded from production through installation of cement plugs or packers. By using relatively simple and inexpensive well rehabilitation methods, water suppliers may be able to decrease exposure of customers to contaminants and avoid costly installation of additional wells, conveyance infrastructure, and treatment technologies.

Significantly enhanced production of acarbose in fed-batch fermentation with the addition of S-adenosylmethionine.

PubMed

Sun, Li-Hui; Li, Ming-Gang; Wang, Yuan-Shan; Zheng, Yu-Guo

2012-06-01

Acarbose, a pseudo-oligosaccharide, is widely used clinically in therapies for non-insulin-dependent diabetes. In the present study, S-adenosylmethionine (SAM) was added to selected media in order to investigate its effect on acarbose fermentation by Actinoplanes utahensis ZJB- 08196. Acarbose titer was seen to increase markedly when concentrations of SAM were added over a period of time. The effects of glucose and maltose on the production of acarbose were investigated in both batch and fed-batch fermentation. Optimal acarbose production was observed at relatively low glucose levels and high maltose levels. Based on these results, a further fed-batch experiment was designed so as to enhance the production of acarbose. Fed-batch fermentation was carried out at an initial glucose level of 10 g/l and an initial maltose level of 60 g/l. Then, 12 h post inoculation, 100 micromol/l SAM was added. In addition, 8 g/l of glucose was added every 24 h, and 20 g/l of maltose was added at 96 h. By way of this novel feeding strategy, the maximum titer of acarbose achieved was 6,113 mg/l at 192 h. To our knowledge, the production level of acarbose achieved in this study is the highest ever reported.

27 CFR 19.318 - Addition of caramel to rum or brandy and addition of oak chips to spirits.

Code of Federal Regulations, 2010 CFR

2010-04-01

... or brandy and addition of oak chips to spirits. 19.318 Section 19.318 Alcohol, Tobacco Products and... PLANTS Production § 19.318 Addition of caramel to rum or brandy and addition of oak chips to spirits. Caramel possessing no material sweetening properties may be added to rum or brandy on bonded premises...

Enhancement of hydrogen production during waste activated sludge anaerobic fermentation by carbohydrate substrate addition and pH control.

PubMed

Chen, Yinguang; Xiao, Naidong; Zhao, Yuxiao; Mu, Hui

2012-06-01

The effects of carbohydrate/protein ratio (CH/Pr) and pH on hydrogen production from waste activated sludge (WAS) were investigated. Firstly, the optimal pH value for hydrogen production was influenced by the CH/Pr ratio, which was pH 10, 9, 8, 8, 8 and 6 at the CH/Pr ratio (COD based) of 0.2 (sole sludge), 1, 2.4, 3.8, 5 and 6.6, respectively. The maximal hydrogen production (100.6 mL/g-COD) was achieved at CH/Pr of 5 and pH 8, which was due to the synergistic effect of carbohydrate addition on hydrogen production, the enhancement of sludge protein degradation and protease and amylase activities, and the suitable fermentation pathway for hydrogen production. As hydrogen consumption was observed at pH 8, in order to further increase hydrogen production a two-step pH control strategy (pH 8+pH 10) was developed and the hydrogen production was further improved by 17.6%. Copyright © 2012 Elsevier Ltd. All rights reserved.

[Research strategies for feed additives and veterinary medicines from side products of Chinese medicine resources industrialization].

PubMed

Zhao, Ming; Duan, Jin-Ao; Zhang, Sen; Guo, Sheng; Su, Shu-Lan; Wu, Qi-Nan; Tang, Yu-Ping; Zeng, Jian-Guo

2017-09-01

The global antimicrobial resistance has been a big challenge to the human health for years. It has to make balance between the safety of animal products and the use of antimicrobials in animal husbandry. Any methods that can minimize or even phase out the use of antimicrobials in animal husbandry should be encouraged. We herein describe the research strategies for feed additives and veterinary medicines from the side products of Chinese medicine resources industrialization. Killing two birds with one stone-besides the major purposes, the rational utilization of non-medicinal parts and wastes of industrialization of Chinese herbal medicines is also achieved under the proposed strategies. Copyright© by the Chinese Pharmaceutical Association.

PILOT-SCALE STUDIES ON THE EFFECT OF BROMINE ADDITION ON THE EMISSIONS OF CHLORINATED ORGANIC COMBUSTION BY-PRODUCTS

EPA Science Inventory

The addition of brominated organic compounds to the feed of a pilot-scale incinerator burning chlorinated waste has been found previously, under some circumstances, to enhance emissions of volatile and semivolatile organic chlorinated products of incomplete combustion (PiCs) incl...

Enantioselective ProPhenol-catalyzed addition of 1,3-diynes to aldehydes to generate synthetically versatile building blocks and diyne natural products.

PubMed

Trost, Barry M; Chan, Vincent S; Yamamoto, Daisuke

2010-04-14

A highly enantioselective method for the catalytic addition of terminal 1,3-diynes to aldehydes was developed using our dinuclear zinc ProPhenol (1) system. Furthermore, triphenylphosphine oxide was found to interact synergistically with the catalyst to substantially enhance the chiral recognition. The generality of this catalytic transformation was demonstrated with aryl, alpha,beta-unsaturated and saturated aldehydes, of which the latter were previously limited in alkynyl zinc additions. The chiral diynol products are also versatile building blocks that can be readily elaborated; this was illustrated through highly selective trans-hydrosilylations, which enabled the synthesis of a beta-hydroxyketone and enyne. Additionally, the development of this method allowed for the rapid total syntheses of several biologically important diynol-containing natural products.

Increase of methane formation by ethanol addition during continuous fermentation of biogas sludge.

PubMed

Refai, Sarah; Wassmann, Kati; van Helmont, Sebastian; Berger, Stefanie; Deppenmeier, Uwe

2014-12-01

Very recently, it was shown that the addition of acetate or ethanol led to enhanced biogas formation rates during an observation period of 24 h. To determine if increased methane production rates due to ethanol addition can be maintained over longer time periods, continuous reactors filled with biogas sludge were developed which were fed with the same substrates as the full-scale reactor from which the sludge was derived. These reactors are well reflected conditions of a full-scale biogas plant during a period of 14 days. When the fermenters were pulsed with 50-100 mM ethanol, biomethanation increased by 50-150 %, depending on the composition of the biogas sludge. It was also possible to increase methane formation significantly when 10-20 mM pure ethanol or ethanolic solutions (e.g. beer) were added daily. In summary, the experiments revealed that "normal" methane production continued to take place, but ethanol led to production of additional methane.

Qualitative Analysis of Additives in Plastic Marine Debris and Its New Products.

PubMed

Rani, Manviri; Shim, Won Joon; Han, Gi Myung; Jang, Mi; Al-Odaini, Najat Ahmed; Song, Young Kyong; Hong, Sang Hee

2015-10-01

Due to their formulation and/or processing, plastics contain additives and impurities that may leach out under conditions of use and accumulate in the environment. To evaluate their role as vectors of chemical contaminants in marine environment, plastic debris (n = 19) collected from coastal beaches along with new plastics (n = 25; same or same brand) bought from local markets were screened by gas chromatography-mass spectrometry in full scan mode. Detected peaks were identified using NIST library in different polymers (polypropylene (PP) > polyethylene (PE) > PP + PE > polyethyl terephthalate > poly(acylene:styrene) with different use (food, fishery, and general use). A database on the presence of 231 different chemicals were grouped into hydrocarbons, ultra-violet (UV)-stabilizers, antioxidants, plasticizers, lubricants, intermediates, compounds for dyes and inks, flame retardants, etc. The UV326, UV327, UV328, UV320, UvinualMC80, irganox 1076, DEHP, antioxidant no 33, di-n-octylisophthalate, diisooctyl phthalate, hexanoic acid 2-ethyl-hexadecyl ester, and hydrocarbons were most frequently detected. Finding of toxic phthalates and UV stabilizers in those products having moisture contact (like bottles with short use) raised concern to humans and indicated their irregular use. The comparison between new and debris plastics clearly indicated the leaching and absorption of chemicals and supports our assumption of plastic as media for transferring these additives in marine environment.

Reactivity of Dazomet, a Hydraulic Fracturing Additive: Hydrolysis and Interaction with Pyrite

NASA Astrophysics Data System (ADS)

Consolazio, N.; Lowry, G. V.; Karamalidis, A.; Hakala, A.

2015-12-01

The Marcellus Shale is currently the largest shale gas formation in play across the world. The low-permeability formation requires hydraulic fracturing to be produced. In this process, millions of gallons of water are blended with chemical additives and pumped into each well to fracture the reservoir rock. Although additives account for less than 2% of the fracking fluid mixture, they amount to hundreds of tons per frack job. The environmental properties of some of these additives have been studied, but their behavior under downhole conditions is not widely reported in the peer-reviewed literature. These compounds and their reaction products may return to the surface as produced or waste water. In the event of a spill or release, this water has the potential to contaminate surface soil and water. Of these additives, biocides may present a formidable challenge to water quality. Biocides are toxic compounds (by design), typically added to the Marcellus Shale to control bacteria in the well. An assessment of the most frequently used biocides indicated a need to study the chemical dazomet under reservoir conditions. The Marcellus Shale contains significant deposits of pyrite. This is a ubiquitous mineral within black shales that is known to react with organic compounds in both oxic and anoxic settings. Thus, the objective of our study was to determine the effect of pyrite on the hydrolysis of dazomet. Liquid chromatography-triple quadrupole mass spectrometry (LC-QQQ) was used to calculate the loss rate of aqueous dazomet. Gas chromatography-mass spectrometry (GC-MS) was used to identify the reaction products. Our experiments show that in water, dazomet rapidly hydrolyses in water to form organic and inorganic transformation products. This reaction rate was unaffected when performed under anoxic conditions. However, with pyrite we found an appreciable increase in the removal rate of dazomet. This was accompanied by a corresponding change in the distribution of observed

Additive Manufacturing Infrared Inspection

NASA Technical Reports Server (NTRS)

Gaddy, Darrell; Nettles, Mindy

2015-01-01

The Additive Manufacturing Infrared Inspection Task started the development of a real-time dimensional inspection technique and digital quality record for the additive manufacturing process using infrared camera imaging and processing techniques. This project will benefit additive manufacturing by providing real-time inspection of internal geometry that is not currently possible and reduce the time and cost of additive manufactured parts with automated real-time dimensional inspections which deletes post-production inspections.

Identification of leachable impurities in an ophthalmic drug product originating from a polymer additive Irganox 1010 using mass spectroscopy.

PubMed

Singh, Gagandeep; Gollapalli, Ramarao; Blinder, Alejandro; Patel, Milan

2018-04-15

Pharmaceutical packaging employs a wide variety of polymers owing to their desirable features, but the compounds that could leach from the polymers into the drug products can pose serious health risks. Therefore, it is extremely important to identify such compounds so that they can be adequately quantified and evaluated for toxicological impact/safety assessments. Not only the polymer components and the additives should be considered as sources for leachable impurities, their reaction/degradation products should also be evaluated. Irganox 1010 is a common commercial antioxidant (polymer additive) used in the manufacturing of polyolefin materials for container closure systems. In our study, we identified two Irganox1010 related leachable impurities in an ophthalmic drug product using rapid and straightforward orthogonal mass spectroscopy (LC-MS and GC-MS) methods The identified impurities were 7,9-Di-tert-butyl-1 oxaspiro[4.5]deca-6,9-diene-2,8-dione and 3-[3,5-bis(tert-butyl)-1-hydroxy-4-oxocyclohexa-2,5-dienyl]propanoic acid which leached into the ophthalmic drug solution during storage. The analytical methods employed could potentially be used to identify the similar class of compounds as is or in drug products. Copyright © 2018 Elsevier B.V. All rights reserved.

30 CFR 203.43 - To which production do I apply the RSV earned from qualified deep wells or qualified phase 1...

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 2 2014-07-01 2014-07-01 false To which production do I apply the RSV earned... production do I apply the RSV earned from qualified deep wells or qualified phase 1 ultra-deep wells on my lease? (a) You must apply the RSV prescribed in § 203.41(b) and (c) to gas volumes produced from...

30 CFR 203.43 - To which production do I apply the RSV earned from qualified deep wells or qualified phase 1...

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 2 2013-07-01 2013-07-01 false To which production do I apply the RSV earned... production do I apply the RSV earned from qualified deep wells or qualified phase 1 ultra-deep wells on my lease? (a) You must apply the RSV prescribed in § 203.41(b) and (c) to gas volumes produced from...

30 CFR 203.43 - To which production do I apply the RSV earned from qualified deep wells or qualified phase 1...

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 2 2012-07-01 2012-07-01 false To which production do I apply the RSV earned... production do I apply the RSV earned from qualified deep wells or qualified phase 1 ultra-deep wells on my lease? (a) You must apply the RSV prescribed in § 203.41(b) and (c) to gas volumes produced from...

Effect of silica-palm shell carbon composite additive in enhancing the strength of the concrete in the oil-well cementing job

NASA Astrophysics Data System (ADS)

Novriansyah, A.; Mursyidah, U.; Novrianti; Putri, S. S.; Riswati, S. S.

2018-04-01

This study provides an analysis of composite additive effect to concrete’s strength in the oil-well cementing job. The composite additive is originated from the nano-sized form of silica and charcoal from palm shell waste. The quality of the concrete will be determined from its porosity, compressive strength, and shear bond strength parameters. Those parameters must be reliable base on the most respectable standards in oil and gas industry, in this study we use the standard from American Petroleum Institute (API). Six concrete samples with different concentration will be tested to obtain these parameters. The result from the test shown a decrement trend of the porosity while the concentration is increased. In contrast, the highest values of compressive strength and shear bond strength are obtained from the sample with higher additive concentration. The optimum strength was obtained in sample with 0.02% The results become clearly proven through verification by scanning electron image where the additive has successfully fill the voids in the concrete’s sample, resulting in strength enhancement of the sample.

Recombinant organisms for production of industrial products.

PubMed

Adrio, Jose-Luis; Demain, Arnold L

2010-01-01

A revolution in industrial microbiology was sparked by the discoveries of ther double-stranded structure of DNA and the development of recombinant DNA technology. Traditional industrial microbiology was merged with molecular biology to yield improved recombinant processes for the industrial production of primary and secondary metabolites, protein biopharmaceuticals and industrial enzymes. Novel genetic techniques such as metabolic engineering, combinatorial biosynthesis and molecular breeding techniques and their modifications are contributing greatly to the development of improved industrial processes. In addition, functional genomics, proteomics and metabolomics are being exploited for the discovery of novel valuable small molecules for medicine as well as enzymes for catalysis. The sequencing of industrial microbal genomes is being carried out which bodes well for future process improvement and discovery of new industrial products. © 2010 Landes Bioscience

Recombinant organisms for production of industrial products

PubMed Central

Adrio, Jose-Luis

2010-01-01

A revolution in industrial microbiology was sparked by the discoveries of ther double-stranded structure of DNA and the development of recombinant DNA technology. Traditional industrial microbiology was merged with molecular biology to yield improved recombinant processes for the industrial production of primary and secondary metabolites, protein biopharmaceuticals and industrial enzymes. Novel genetic techniques such as metabolic engineering, combinatorial biosynthesis and molecular breeding techniques and their modifications are contributing greatly to the development of improved industrial processes. In addition, functional genomics, proteomics and metabolomics are being exploited for the discovery of novel valuable small molecules for medicine as well as enzymes for catalysis. The sequencing of industrial microbal genomes is being carried out which bodes well for future process improvement and discovery of new industrial products. PMID:21326937

Numerical simulation of Forchheimer flow to a partially penetrating well with a mixed-type boundary condition

NASA Astrophysics Data System (ADS)

Mathias, Simon A.; Wen, Zhang

2015-05-01

This article presents a numerical study to investigate the combined role of partial well penetration (PWP) and non-Darcy effects concerning the performance of groundwater production wells. A finite difference model is developed in MATLAB to solve the two-dimensional mixed-type boundary value problem associated with flow to a partially penetrating well within a cylindrical confined aquifer. Non-Darcy effects are incorporated using the Forchheimer equation. The model is verified by comparison to results from existing semi-analytical solutions concerning the same problem but assuming Darcy's law. A sensitivity analysis is presented to explore the problem of concern. For constant pressure production, Non-Darcy effects lead to a reduction in production rate, as compared to an equivalent problem solved using Darcy's law. For fully penetrating wells, this reduction in production rate becomes less significant with time. However, for partially penetrating wells, the reduction in production rate persists for much larger times. For constant production rate scenarios, the combined effect of PWP and non-Darcy flow takes the form of a constant additional drawdown term. An approximate solution for this loss term is obtained by performing linear regression on the modeling results.

Complete genome sequence of Campylobacter concisus ATCC 33237T and draft genome sequences for an additional eight well-characterized C. concisus strains

USDA-ARS?s Scientific Manuscript database

This report includes the complete genome of the Campylobacter concisus type strain ATCC 33237T and the draft genomes of eight additional well characterized C. concisus genomes. C. concisus has been shown to be a genetically heterogeneous species and these nine genomes provide valuable information re...

Additive Manufacturing in Production: A Study Case Applying Technical Requirements

NASA Astrophysics Data System (ADS)

Ituarte, Iñigo Flores; Coatanea, Eric; Salmi, Mika; Tuomi, Jukka; Partanen, Jouni

Additive manufacturing (AM) is expanding the manufacturing capabilities. However, quality of AM produced parts is dependent on a number of machine, geometry and process parameters. The variability of these parameters affects the manufacturing drastically and therefore standardized processes and harmonized methodologies need to be developed to characterize the technology for end use applications and enable the technology for manufacturing. This research proposes a composite methodology integrating Taguchi Design of Experiments, multi-objective optimization and statistical process control, to optimize the manufacturing process and fulfil multiple requirements imposed to an arbitrary geometry. The proposed methodology aims to characterize AM technology depending upon manufacturing process variables as well as to perform a comparative assessment of three AM technologies (Selective Laser Sintering, Laser Stereolithography and Polyjet). Results indicate that only one machine, laser-based Stereolithography, was feasible to fulfil simultaneously macro and micro level geometrical requirements but mechanical properties were not at required level. Future research will study a single AM system at the time to characterize AM machine technical capabilities and stimulate pre-normative initiatives of the technology for end use applications.

Food additives used in meat processing according to the Polish and European Union legislation.

PubMed

Uradziński, J; Weiner, M

2003-01-01

This paper presents the legal regulations related to the use of food additives in meat production in Poland and the European Union. The Polish legal definition of food additives is given as well as the classification of permitted food additives added to food and stimulants by their technological function. In addition, a definition of processing aids in the food industry is included. It shows that Polish legislation includes food additives used to ensure or improve food nutritional value, whereas in the EU legislation, these substances are not included in the list of food additives. Moreover, the Council Directives include food additive specific purity criteria, whereas the Polish regulations do not mention the legal regulations of this issue in practice. The European Union use mechanisms and procedures for the introduction of new food additives into internal markets as well as controlling the circulation of additives. The Polish legislation in practice, however, does not determine approval or methods for the introduction of new food additives to the market. Legal regulations on the monitoring of food additives no exist.

The influence of α-Al2O3 addition on microstructure, mechanical and formaldehyde adsorption properties of fly ash-based geopolymer products.

PubMed

Huang, Yi; Han, Minfang

2011-10-15

Fly ash-based geopolymer with α-Al(2)O(3) addition were synthesized and used to remove formaldehyde from indoor air. The microstructure, mechanical and formaldehyde adsorption properties of the geopolymer products obtained were investigated. The results showed that α-Al(2)O(3) addition with appropriate amount (such as 5 wt%) increased the geopolymerization extent, resulting in the increase of surface area and compressive strength. In addition, the improvement of structural ordering level for geopolymer sample with 5 wt% α-Al(2)O(3) addition was found through FTIR analysis. By contrast, excessive addition (such as 10 wt%) had the opposite effect. The test of formaldehyde adsorption capacity confirmed that fly ash-based geopolymer product exhibited much better property of adsorbing indoor formaldehyde physically and chemically than fly ash itself. The surface area was an important but not unique factor influencing the adsorption capacity of geopolymers. Copyright © 2011 Elsevier B.V. All rights reserved.

Primary broiler breeding--striking a balance between economic and well-being traits.

PubMed

Katanbaf, M N; Hardiman, J W

2010-04-01

Primary breeders are well aware that selecting for better health and well-being along with economic traits such as faster growth rate, higher levels of meat yield, and improved efficiency of feed utilization are critical to balanced long-term genetic progress of their pure lines as well as to increased production efficiency of broiler products for the broiler industry. Cobb collects and selects on over 50 phenotypic observations per pedigree candidate at various ages. Over 50% of these collections are involved with evaluation of each bird's health, welfare, and fitness. Some examples of these traits are various chick defects, various broiler age skeletal and leg abnormalities, feather cover, various physiological measures of heart and lung functions, and specific causes of mortality. Large pedigree populations, massive data collection infrastructure, integration of better technologies in evaluation of phenotypes, and sophisticated data analysis capability have allowed geneticists to perform selections that are balanced for both economic and welfare traits. Cobb's internal as well as worldwide sponsored research has facilitated geneticists to make science-based breeding decisions. Each pedigree line per product available to primary breeders exhibits their own unique characteristics that are enhanced by selective breeding and positioned in special mating schemes to produce the product and welfare performance that our customers demand. Additionally, most if not all primary breeding companies now offer different products for different markets that exhibit varying levels of performance and behavior to fit customer needs. Future expansion of these products and creation of new products by breeding companies will be in large dictated by both our customers and consumers.

Microbial diversity and methanogenic activity of Antrim Shale formation waters from recently fractured wells

PubMed Central

Wuchter, Cornelia; Banning, Erin; Mincer, Tracy J.; Drenzek, Nicholas J.; Coolen, Marco J. L.

2013-01-01

The Antrim Shale in the Michigan Basin is one of the most productive shale gas formations in the U.S., but optimal resource recovery strategies must rely on a thorough understanding of the complex biogeochemical, microbial, and physical interdependencies in this and similar systems. We used Illumina MiSeq 16S rDNA sequencing to analyze the diversity and relative abundance of prokaryotic communities present in Antrim shale formation water of three closely spaced recently fractured gas-producing wells. In addition, the well waters were incubated with a suite of fermentative and methanogenic substrates in an effort to stimulate microbial methane generation. The three wells exhibited substantial differences in their community structure that may arise from their different drilling and fracturing histories. Bacterial sequences greatly outnumbered those of archaea and shared highest similarity to previously described cultures of mesophiles and moderate halophiles within the Firmicutes, Bacteroidetes, and δ- and ε-Proteobacteria. The majority of archaeal sequences shared highest sequence similarity to uncultured euryarchaeotal environmental clones. Some sequences closely related to cultured methylotrophic and hydrogenotrophic methanogens were also present in the initial well water. Incubation with methanol and trimethylamine stimulated methylotrophic methanogens and resulted in the largest increase in methane production in the formation waters, while fermentation triggered by the addition of yeast extract and formate indirectly stimulated hydrogenotrophic methanogens. The addition of sterile powdered shale as a complex natural substrate stimulated the rate of methane production without affecting total methane yields. Depletion of methane indicative of anaerobic methane oxidation (AMO) was observed over the course of incubation with some substrates. This process could constitute a substantial loss of methane in the shale formation. PMID:24367357

Enzymatic Pretreatment Coupled with the Addition of p-Hydroxyanisole Increased Levulinic Acid Production from Steam-Exploded Rice Straw Short Fiber.

PubMed

Ma, Li-Tong; Zhao, Zhi-Min; Yu, Bin; Chen, Hong-Zhang

2016-11-01

Levulinic acid production, directly from lignocellulosic biomass, resulted in low yields due to the poor substrate accessibility and occurrence of side reactions. The effects of reaction conditions, enzymatic pretreatment, and inhibitor addition on the conversion of steam-exploded rice straw (SERS) short fiber to levulinic acid catalyzed by solid superacid were investigated systematically. The results indicated that the optimal reaction conditions were temperature, time, and solid superacid concentration combinations of 200 °C, 15 min, and 7.5 %. Enzymatic pretreatment improved the substrate accessibility to solid superacid catalyst, and p-hydroxyanisole inhibitor reduced the side reactions during reaction processes, which helped to increase levulinic acid yield. The levulinic acid yield reached 25.2 % under the optimal conditions, which was 61.5 % higher than that without enzymatic pretreatment and inhibitor addition. Therefore, enzymatic pretreatment coupled with the addition of p-hydroxyanisole increased levulinic acid production effectively, which contributed to the value-added utilization of lignocellulosic biomass.

Evaluation of production tests in oil wells stimulated by massive acid fracturing offshore Qatar

DOE Office of Scientific and Technical Information (OSTI.GOV)

McDonald, S.W.

This paper presents the evaluation of pressure-buildup data from production tests in wells that have been stimulated by massive acid fracturing. Fracture type curves are used in combination with conventional semilog analysis techniques. Fracture characteristics are calculated from a match of the early-time pressure data with the type curves, and reservoir characteristics are calculated from a conventional semilog plot of late-time data. Unexpectedly high formation permeabilities are evaluated, and fracture half-lengths are much shorter than design values.

Additive manufacturing of liquid/gas diffusion layers for low-cost and high-efficiency hydrogen production

DOE PAGES

Mo, Jingke; Zhang, Feng -Yuan; Dehoff, Ryan R.; ...

2016-01-14

The electron beam melting (EBM) additive manufacturing technology was used to fabricate titanium liquid/gas diffusion media with high-corrosion resistances and well-controllable multifunctional parameters, including two-phase transport and excellent electric/thermal conductivities, has been first demonstrated. Their applications in proton exchange membrane eletrolyzer cells have been explored in-situ in a cell and characterized ex-situ with SEM and XRD. Compared with the conventional woven liquid/gas diffusion layers (LGDLs), much better performance with EBM fabricated LGDLs is obtained due to their significant reduction of ohmic loss. The EBM technology components exhibited several distinguished advantages in fabricating gas diffusion layer: well-controllable pore morphology and structure,more » rapid prototyping, fast manufacturing, highly customizing and economic. In addition, by taking advantage of additive manufacturing, it possible to fabricate complicated three-dimensional designs of virtually any shape from a digital model into one single solid object faster, cheaper and easier, especially for titanium. More importantly, this development will provide LGDLs with control of pore size, pore shape, pore distribution, and therefore porosity and permeability, which will be very valuable to develop modeling and to validate simulations of electrolyzers with optimal and repeatable performance. Further, it will lead to a manufacturing solution to greatly simplify the PEMEC/fuel cell components and to couple the LGDLs with other parts, since they can be easily integrated together with this advanced manufacturing process« less

Enhanced production of acarbose and concurrently reduced formation of impurity c by addition of validamine in fermentation of Actinoplanes utahensis ZJB-08196.

PubMed

Xue, Ya-Ping; Qin, Jun-Wei; Wang, Ya-Jun; Wang, Yuan-Shan; Zheng, Yu-Guo

2013-01-01

Commercial production of acarbose is exclusively via done microbial fermentation with strains from the genera of Actinoplanes. The addition of C7N-aminocyclitols for enhanced production of acarbose and concurrently reduced formation of impurity C by cultivation of A. utahensis ZJB-08196 in 500-mL shake flasks was investigated, and validamine was found to be the most effective strategy. Under the optimal conditions of validamine addition, acarbose titer was increased from 3560 ± 128 mg/L to 4950 ± 156 mg/L, and impurity C concentration was concurrently decreased from 289 ± 24 mg/L to 107 ± 29 mg/L in batch fermentation after 168 h of cultivation. A further fed-batch experiment coupled with the addition of validamine (20 mg/L) in the fermentation medium prior to inoculation was designed to enhance the production of acarbose. When twice feedings of a mixture of 6 g/L glucose, 14 g/L maltose, and 9 g/L soybean flour were performed at 72 h and 96 h, acarbose titer reached 6606 ± 103 mg/L and impurity C concentration was only 212 ± 12 mg/L at 168 h of cultivation. Acarbose titer and proportion of acarbose/impurity C increased by 85.6% and 152.9% when compared with control experiments. This work demonstrates for the first time that validamine addition is a simple and effective strategy for increasing acarbose production and reducing impurity C formation.

Chemical stabilization of polymers: Implications for dermal exposure to additives.

PubMed

Bartsch, N; Girard, M; Schneider, L; Weijgert, V Van De; Wilde, A; Kappenstein, O; Vieth, B; Hutzler, C; Luch, A

2018-04-16

Technical benefits of additives in polymers stand in marked contrast to their associated health risks. Here, a multi-analyte method based on gas chromatography coupled to tandem mass spectrometry (GC-MS/MS) was developed to quantify polymer additives in complex matrices such as low-density polyethylene (LDPE) and isolated human skin layers after dermal exposure ex vivo. That way both technical aspects and dermal exposure were investigated. The effects of polymer additivation on the material were studied using the example of LDPE. To this end, a tailor-made polymer was applied in aging studies that had been furnished with two different mixtures of phenol- and diarylamine-based antioxidants, plasticizers and processing aids. Upon accelerated thermo-oxidative aging of the material, the formation of LDPE degradation products was monitored with attenuated total reflectance-Fourier transformed infrared (ATR-FTIR) spectroscopy. Compared to pure LDPE, a protective effect of added antioxidants could be observed on the integrity of the polymer. Further, thermo-oxidative degradation of the additives and its kinetics were investigated using LDPE or squalane as matrix. The half-lives of additives in both matrices revealed significant differences between the tested additives as well as between LDPE and squalane. For instance, 2-tert-butyl-6-[(3-tert-butyl-2-hydroxy-5-methylphenyl)methyl]-4-methylphenol (Antioxidant 2246) showed a half-life 12 times lower when incorporated in LDPE as compared to squalane. As a model for dermal exposure of consumers, human skin was brought into contact with the tailor-made LDPE containing additives ex vivo in static Franz diffusion cells. The skin was then analyzed for additives and decomposition products. This study proved 10 polymer additives of diverse pysicochemical properties and functionalities to migrate out of the polymer and eventually overcome the intact human skin barrier during contact. Moreover, their individual distribution within

Methane and benzene in drinking-water wells overlying the Eagle Ford, Fayetteville, and Haynesville Shale hydrocarbon production areas

USGS Publications Warehouse

McMahon, Peter B.; Barlow, Jeannie R.; Engle, Mark A.; Belitz, Kenneth; Ging, Patricia B.; Hunt, Andrew G.; Jurgens, Bryant; Kharaka, Yousif K.; Tollett, Roland W.; Kresse, Timothy M.

2017-01-01

Water wells (n = 116) overlying the Eagle Ford, Fayetteville, and Haynesville Shale hydrocarbon production areas were sampled for chemical, isotopic, and groundwater-age tracers to investigate the occurrence and sources of selected hydrocarbons in groundwater. Methane isotopes and hydrocarbon gas compositions indicate most of the methane in the wells was biogenic and produced by the CO2 reduction pathway, not from thermogenic shale gas. Two samples contained methane from the fermentation pathway that could be associated with hydrocarbon degradation based on their co-occurrence with hydrocarbons such as ethylbenzene and butane. Benzene was detected at low concentrations (<0.15 μg/L), but relatively high frequencies (2.4–13.3% of samples), in the study areas. Eight of nine samples containing benzene had groundwater ages >2500 years, indicating the benzene was from subsurface sources such as natural hydrocarbon migration or leaking hydrocarbon wells. One sample contained benzene that could be from a surface release associated with hydrocarbon production activities based on its age (10 ± 2.4 years) and proximity to hydrocarbon wells. Groundwater travel times inferred from the age-data indicate decades or longer may be needed to fully assess the effects of potential subsurface and surface releases of hydrocarbons on the wells.

Methane and Benzene in Drinking-Water Wells Overlying the Eagle Ford, Fayetteville, and Haynesville Shale Hydrocarbon Production Areas.

PubMed

McMahon, Peter B; Barlow, Jeannie R B; Engle, Mark A; Belitz, Kenneth; Ging, Patricia B; Hunt, Andrew G; Jurgens, Bryant C; Kharaka, Yousif K; Tollett, Roland W; Kresse, Timothy M

2017-06-20

Water wells (n = 116) overlying the Eagle Ford, Fayetteville, and Haynesville Shale hydrocarbon production areas were sampled for chemical, isotopic, and groundwater-age tracers to investigate the occurrence and sources of selected hydrocarbons in groundwater. Methane isotopes and hydrocarbon gas compositions indicate most of the methane in the wells was biogenic and produced by the CO 2 reduction pathway, not from thermogenic shale gas. Two samples contained methane from the fermentation pathway that could be associated with hydrocarbon degradation based on their co-occurrence with hydrocarbons such as ethylbenzene and butane. Benzene was detected at low concentrations (<0.15 μg/L), but relatively high frequencies (2.4-13.3% of samples), in the study areas. Eight of nine samples containing benzene had groundwater ages >2500 years, indicating the benzene was from subsurface sources such as natural hydrocarbon migration or leaking hydrocarbon wells. One sample contained benzene that could be from a surface release associated with hydrocarbon production activities based on its age (10 ± 2.4 years) and proximity to hydrocarbon wells. Groundwater travel times inferred from the age-data indicate decades or longer may be needed to fully assess the effects of potential subsurface and surface releases of hydrocarbons on the wells.

77 FR 13009 - Regulation of Fuels and Fuel Additives: Identification of Additional Qualifying Renewable Fuel...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-05

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 80 [EPA-HQ-OAR-2011-0542; FRL-9642-3] RIN 2060-AR07 Regulation of Fuels and Fuel Additives: Identification of Additional Qualifying Renewable Fuel Pathways Under... of Sec. 80.1426 to identify additional renewable fuel production pathways and pathway components that...

Significant Change in Marine Plankton Structure and Carbon Production After the Addition of River Water in a Mesocosm Experiment.

PubMed

Fouilland, E; Trottet, A; Alves-de-Souza, C; Bonnet, D; Bouvier, T; Bouvy, M; Boyer, S; Guillou, L; Hatey, E; Jing, H; Leboulanger, C; Le Floc'h, E; Liu, H; Mas, S; Mostajir, B; Nouguier, J; Pecqueur, D; Rochelle-Newall, E; Roques, C; Salles, C; Tournoud, M-G; Vasseur, C; Vidussi, F

2017-08-01

Rivers are known to be major contributors to eutrophication in marine coastal waters, but little is known on the short-term impact of freshwater surges on the structure and functioning of the marine plankton community. The effect of adding river water, reducing the salinity by 15 and 30%, on an autumn plankton community in a Mediterranean coastal lagoon (Thau Lagoon, France) was determined during a 6-day mesocosm experiment. Adding river water brought not only nutrients but also chlorophyceans that did not survive in the brackish mesocosm waters. The addition of water led to initial increases (days 1-2) in bacterial production as well as increases in the abundances of bacterioplankton and picoeukaryotes. After day 3, the increases were more significant for diatoms and dinoflagellates that were already present in the Thau Lagoon water (mainly Pseudo-nitzschia spp. group delicatissima and Prorocentrum triestinum) and other larger organisms (tintinnids, rotifers). At the same time, the abundances of bacterioplankton, cyanobacteria, and picoeukaryote fell, some nutrients (NH 4 + , SiO 4 3- ) returned to pre-input levels, and the plankton structure moved from a trophic food web based on secondary production to the accumulation of primary producers in the mesocosms with added river water. Our results also show that, after freshwater inputs, there is rapid emergence of plankton species that are potentially harmful to living organisms. This suggests that flash flood events may lead to sanitary issues, other than pathogens, in exploited marine areas.

SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scott Reeves

2003-03-01

Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) The contract was signed on August 20, 2000. Little work has been performed other than preliminary planning to get the project underway.« less

SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scott Reeves

2003-03-01

Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Continued coordinating the final selection of candidates and field implementation with Oneok. Oneok plans on performing the operations early in 2003.« less

SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scott Reeves

2003-03-01

Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Finished preparing the final project report, less the field implementation component. Sent to DOE for review. (2) Continued coordinating the final selection of candidates and field implementation with Oneok. Oneok

SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scott Reeves

2003-03-01

Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Began preparing final project report, less the field implementation component. (2) Coordinated the final selection of candidates and field implementation with Oneok.« less

SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scott Reeves

2003-04-01

Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: Continued coordinating the final selection of candidates and field implementation with Oneok. Oneok plans on performing the operations early in 2003.« less

Suitability of histopathology as an additional endpoint to the Isolated Chicken Eye Test for classification of non-extreme pH detergent and cleaning products.

PubMed

Cazelle, Elodie; Eskes, Chantra; Hermann, Martina; Jones, Penny; McNamee, Pauline; Prinsen, Menk; Taylor, Hannah; Wijnands, Marcel V W

2014-06-01

A.I.S.E. investigated the suitability of histopathological evaluations as an additional endpoint to the regulatory adopted ICE in vitro test method (OECD TG 438) to identify non-extreme pH detergent and cleaning products that require classification as EU CLP/UN GHS Category 1 (serious eye damage). To this aim, a total of 30 non-extreme pH products covering the range of in vivo classifications for eye irritation, and representing various product categories were tested. Epithelium vacuolation (mid and lower layers) and erosion (at least moderate) were found to be the most relevant histopathological effects induced by products classified in vivo as Category 1. Histopathology criteria specifically developed for non-extreme pH detergent and cleaning products were shown to correctly identify materials classified as Category 1 based on in vivo persistent effects, and to significantly increase the overall sensitivity of the standard ICE prediction model for Category 1 identification (to 75%) whilst maintaining a good concordance (73%). In contrast, use of EU CLP additivity approach for classification of mixtures was considerably less predictive, with a concordance of only 27%, and 100% over-predictions of non-Category 1 products. As such, use of histopathology as an addition to the ICE test method was found suitable to identify EU CLP/UN GHS Category 1 non-extreme pH detergent and cleaning products and to allow a better discrimination from Category 2 products. Copyright © 2014 Elsevier Ltd. All rights reserved.

Feed additive production by fermentation of herb Polygonum hydropiper L. and cassava pulp with simultaneous flavonoid dissolution.

PubMed

Song, Zhen-Tao; Zhu, Ming-Jun

2017-03-01

Fermentation of herb Polygonum hydropiper L. (PHL) and cassava pulp (CP) for feed additive production with simultaneous flavonoid dissolution was investigated, and a two-stage response surface methodology (RSM) based on Plackett-Burman factorial design (PB design) was used to optimize the flavonoid dissolution and protein content. Using the screening function of PB design, four different significant factors for the two response variables were acquired: factors A (CP) and B (PHL) for the flavonoid dissolution versus factors G (inoculum size) and H (fermentation time) for protein content. Then, two RSMs were used sequentially to improve the values of the two response variables separately. The mutual corroboration of the experimental results in the present study confirmed the validity of the associated experimental design. The validation experiment showed a flavonoid dissolution rate of 94.00%, and a protein content of 18.20%, gaining an increase in 21.20% and 199.10% over the control, respectively. The present study confirms the feasibility of feed additive production by Saccharomyces cerevisiae with CP and PHL and simultaneous optimization of flavonoid dissolution and protein content using a two-stage RSM. © 2016 International Union of Biochemistry and Molecular Biology, Inc.

Impact of Hydraulic Well Restoration on Native Bacterial Communities in Drinking Water Wells

PubMed Central

Karwautz, Clemens; Lueders, Tillmann

2014-01-01

The microbial monitoring of drinking water production systems is essential to assure water quality and minimize possible risks. However, the comparative impact of microbes from the surrounding aquifer and of those established within drinking water wells on water parameters remains poorly understood. High pressure jetting is a routine method to impede well clogging by fine sediments and also biofilms. In the present study, bacterial communities were investigated in a drinking water production system before, during, and after hydraulic purging. Variations were observed in bacterial communities between different wells of the same production system before maintenance, despite them having practically identical water chemistries. This may have reflected the distinct usage practices of the different wells, and also local aquifer heterogeneity. Hydraulic jetting of one well preferentially purged a subset of the dominating taxa, including lineages related to Diaphorobacter, Nitrospira, Sphingobium, Ralstonia, Alkanindiges, Janthinobacterium, and Pseudomonas spp, suggesting their tendency for growth in well-associated biofilms. Lineages of potential drinking water concern (i.e. Legionellaceae, Pseudomonadaceae, and Acinetobacter spp.) reacted distinctly to hydraulic jetting. Bacterial diversity was markedly reduced in drinking water 2 weeks after the cleaning procedure. The results of the present study provide a better understanding of drinking water wells as a microbial habitat, as well as their role in the microbiology of drinking water systems. PMID:25273229

Impact of hydraulic well restoration on native bacterial communities in drinking water wells.

PubMed

Karwautz, Clemens; Lueders, Tillmann

2014-01-01

The microbial monitoring of drinking water production systems is essential to assure water quality and minimize possible risks. However, the comparative impact of microbes from the surrounding aquifer and of those established within drinking water wells on water parameters remains poorly understood. High pressure jetting is a routine method to impede well clogging by fine sediments and also biofilms. In the present study, bacterial communities were investigated in a drinking water production system before, during, and after hydraulic purging. Variations were observed in bacterial communities between different wells of the same production system before maintenance, despite them having practically identical water chemistries. This may have reflected the distinct usage practices of the different wells, and also local aquifer heterogeneity. Hydraulic jetting of one well preferentially purged a subset of the dominating taxa, including lineages related to Diaphorobacter, Nitrospira, Sphingobium, Ralstonia, Alkanindiges, Janthinobacterium, and Pseudomonas spp, suggesting their tendency for growth in well-associated biofilms. Lineages of potential drinking water concern (i.e. Legionellaceae, Pseudomonadaceae, and Acinetobacter spp.) reacted distinctly to hydraulic jetting. Bacterial diversity was markedly reduced in drinking water 2 weeks after the cleaning procedure. The results of the present study provide a better understanding of drinking water wells as a microbial habitat, as well as their role in the microbiology of drinking water systems.

Health-risk assessment based on an additive to paints made from isobutyric aldehyde condensation products

NASA Astrophysics Data System (ADS)

Jan Tic, Wilhelm

2017-10-01

Solvents are primarily used for making protective coatings. Considering their chemical nature, there are a great variety of coatings, including those based on liquid hydrocarbons and organic chloroderivatives. These products are a serious load to the environment because of their physicochemical properties, therefore, they have for some time been replaced with more-environmentally friendly, new generation products. One of them is the hydroxyester HE-1: made from isobutyric aldehyde condensation products, it is an alternative to those coalescents for paints and varnishes which are intended to be replaced or their use restricted. The results of selected toxicological tests relating to the human health risk effect of the hydroxyester HE-1 - environmentally-friendly additive to paints and varnishes are presented. The test results indicate that HE-1 causes skin irritation in rabbit only when used at its maximum concentrations. No lesions in the cornea or iris were observed in any of the test rabbits after the application of the hydroxyester HE-1. In the mutagenic effect test of HE-1 on the bacteria Salmonella typhimurium, the result was negative. Based on the test results, it was found that the hydroxyester HE-1 may only have a human health risk effect when used at its maximum concentrations.

Variation in Methane Emission Rates from Well Pads in Four Oil and Gas Basins with Contrasting Production Volumes and Compositions.

PubMed

Robertson, Anna M; Edie, Rachel; Snare, Dustin; Soltis, Jeffrey; Field, Robert A; Burkhart, Matthew D; Bell, Clay S; Zimmerle, Daniel; Murphy, Shane M

2017-08-01

Atmospheric methane emissions from active natural gas production sites in normal operation were quantified using an inverse Gaussian method (EPA's OTM 33a) in four major U.S. basins/plays: Upper Green River (UGR, Wyoming), Denver-Julesburg (DJ, Colorado), Uintah (Utah), and Fayetteville (FV, Arkansas). In DJ, Uintah, and FV, 72-83% of total measured emissions were from 20% of the well pads, while in UGR the highest 20% of emitting well pads only contributed 54% of total emissions. The total mass of methane emitted as a percent of gross methane produced, termed throughput-normalized methane average (TNMA) and determined by bootstrapping measurements from each basin, varied widely between basins and was (95% CI): 0.09% (0.05-0.15%) in FV, 0.18% (0.12-0.29%) in UGR, 2.1% (1.1-3.9%) in DJ, and 2.8% (1.0-8.6%) in Uintah. Overall, wet-gas basins (UGR, DJ, Uintah) had higher TNMA emissions than the dry-gas FV at all ranges of production per well pad. Among wet basins, TNMA emissions had a strong negative correlation with average gas production per well pad, suggesting that consolidation of operations onto single pads may reduce normalized emissions (average number of wells per pad is 5.3 in UGR versus 1.3 in Uintah and 2.8 in DJ).

Additive Layer Manufacturing for Launcher's Applications

NASA Astrophysics Data System (ADS)

Vilanova, J.; Romera, P.; Lasagni, F.; Zorrilla, A.; Perinan, A.

2014-06-01

In the next years the European space industry has the challenge of maintaining its competitiveness in launch vehicles (LV) production, due to the growth of competition worldwide. It has to assure its position developing new applied technologies. In this field the effort is focussed on the production of short series of customized products, like payloads, flight components or launcher parts. ALM (Additive Layer Manufacturing) could be a powerful tool that offers new competitiveness factors for this industry, comprising a set of emerging technologies that are becoming a competitor to forming, casting and machining as well as being utilised directly as a complementary alternative.Originally used for prototypes and models, now ALM becomes a very useful technology capable to fabricate functional parts for the space industrial sector. Its demands on rapid technologies are different to "earth" industries, and they aren't so easily satisfied because space is a field with different requirements depending on its application: launchers, reusable vehicles, satellites, probes, low gravity researches, manned spacecraft, or even moon and planetary exploration.This paper reports on the ALM potential applications, under ESA requirements, exploring the challenges and possibilities for its use in the launchers market, trying to answer two basic questions: the first one, whether ALM is a mature technology to be ready for its use as flight hardware; and the second one, if it can be used to reduce the product cycle, and consequently, the development, production and operational costs.

Newberry Well 55-29 Stimulation Data 2014

DOE Data Explorer

Trenton T. Cladouhos

2015-09-03

The Newberry Volcano EGS Demonstration in central Oregon, a 5 year project begun in 2010, tests recent technological advances designed to reduce the cost of power generated by EGS in a hot, dry well (NWG 55-29) drilled in 2008. First, the stimulation pumps used were designed to run for weeks and deliver large volumes of water at moderate well-head pressure. Second, to stimulate multiple zones, AltaRock developed thermo-degradable zonal isolation materials (TZIMs) to seal off fractures in a geothermal well to stimulate secondary and tertiary fracture zones. The TZIMs degrade within weeks, resulting in an optimized injection/ production profile of the entire well. Third, the project followed a project-specific Induced Seismicity Mitigation Plan (ISMP) to evaluate, monitor for, and mitigate felt induced seismicity. An initial stimulation was conducted in 2012 and continued for 7 weeks, with over 41,000 m3 of water injected. Further analysis indicated a shallow casing leak and an unstable formation in the open hole. The well was repaired with a shallow casing tieback and perforated liner in the open hole and re-stimulated in 2014. The second stimulation started September 23rd, 2014 and continued for 3 weeks with over 9,500 m3 of water injected. The well was treated with several batches of newly tested TZIM diverter materials and a newly designed Diverter Injection Vessel Assembly (DIVA), which was the main modification to the original injection system design used in 2012. A second round of stimulation that included two perforation shots and additional batches of TZIM was conducted on November 11th, 2014 for 9 days with an additional 4,000 m3 of water injected. The stimulations resulted in a 3-4 fold increase in injectivity, and PTS data indicates partial blocking and creation of flow zones near the bottom of the well.

Effect of ensiling and silage additives on biogas production and microbial community dynamics during anaerobic digestion of switchgrass.

PubMed

Zhao, Xiaoling; Liu, Jinhuan; Liu, Jingjing; Yang, Fuyu; Zhu, Wanbin; Yuan, Xufeng; Hu, Yuegao; Cui, Zongjun; Wang, Xiaofen

2017-10-01

Silage processing has a crucial positive impact on the methane yield of anaerobic treated substrates. Changes in the characteristics of switchgrass after ensiling with different additives and their effects on methane production and microbial community changes during anaerobic digestion were investigated. After ensiling (CK), methane yield was increased by 33.59% relative to that of fresh switchgrass (FS). In comparison with the CK treatment, methane production was improved by 17.41%, 13.08% and 8.72% in response to ensiling with LBr+X, LBr and X, respectively. A modified Gompertz model predicted that the optimum treatment was LBr+X, with a potential cumulative methane yield of 178.31mL/g total solids (TS) and a maximum biogas production rate of 44.39mL/g TS·d. Firmicutes and Bacteroidetes were the predominant bacteria in FS and silage switchgrass; however, the switchgrass treated with LBr+X was rich in Synergistetes, which was crucial for methane production. Copyright © 2017. Published by Elsevier Ltd.

Dextransucrase production using cashew apple juice as substrate: effect of phosphate and yeast extract addition.

PubMed

Chagas, Clarice M A; Honorato, Talita L; Pinto, Gustavo A S; Maia, Geraldo A; Rodrigues, Sueli

2007-05-01

Cashew apples are considered agriculture excess in the Brazilian Northeast because cashew trees are cultivated primarily with the aim of cashew nut production. In this work, the use of cashew apple juice as a substrate for Leuconostoc mesenteroides cultivation was investigated. The effect of yeast extract and phosphate addition was evaluated using factorial planning tools. Both phosphate and yeast extract addition were significant factors for biomass growth, but had no significant effect on maximum enzyme activity. The enzyme activities found in cashew apple juice assays were at least 3.5 times higher than the activity found in the synthetic medium. Assays with pH control (pH = 6.5) were also carried out. The pH-controlled fermentation enhanced biomass growth, but decreased the enzyme activity. Crude enzyme free of cells produced using cashew apple juice was stable for 16 h at 30 degrees C at a pH of 5.0.

Enhanced Production of Acarbose and Concurrently Reduced Formation of Impurity C by Addition of Validamine in Fermentation of Actinoplanes utahensis ZJB-08196

PubMed Central

Xue, Ya-Ping; Qin, Jun-Wei; Wang, Ya-Jun; Wang, Yuan-Shan; Zheng, Yu-Guo

2013-01-01

Commercial production of acarbose is exclusively via done microbial fermentation with strains from the genera of Actinoplanes. The addition of C7N-aminocyclitols for enhanced production of acarbose and concurrently reduced formation of impurity C by cultivation of A. utahensis ZJB-08196 in 500-mL shake flasks was investigated, and validamine was found to be the most effective strategy. Under the optimal conditions of validamine addition, acarbose titer was increased from 3560 ± 128 mg/L to 4950 ± 156 mg/L, and impurity C concentration was concurrently decreased from 289 ± 24 mg/L to 107 ± 29 mg/L in batch fermentation after 168 h of cultivation. A further fed-batch experiment coupled with the addition of validamine (20 mg/L) in the fermentation medium prior to inoculation was designed to enhance the production of acarbose. When twice feedings of a mixture of 6 g/L glucose, 14 g/L maltose, and 9 g/L soybean flour were performed at 72 h and 96 h, acarbose titer reached 6606 ± 103 mg/L and impurity C concentration was only 212 ± 12 mg/L at 168 h of cultivation. Acarbose titer and proportion of acarbose/impurity C increased by 85.6% and 152.9% when compared with control experiments. This work demonstrates for the first time that validamine addition is a simple and effective strategy for increasing acarbose production and reducing impurity C formation. PMID:23484146

Productivity and injectivity of horizontal wells. Quarterly report, October 1--December 31, 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fayers, F.J.; Aziz, K.; Hewett, T.A.

1993-03-10

A number of activities have been carried out in the last three months. A list outlining these efforts is presented below followed by brief description of each activity in the subsequent sections of this report: Progress is being made on the development of a black oil three-phase simulator which will allow the use of a generalized Voronoi grid in the plane perpendicular to a horizontal well. The available analytical solutions in the literature for calculating productivity indices (Inflow Performance) of horizontal wells have been reviewed. The pseudo-steady state analytic model of Goode and Kuchuk has been applied to an examplemore » problem. A general mechanistic two-phase flow model is under development. The model is capable of predicting flow transition boundaries for a horizontal pipe at any inclination angle. It also has the capability of determining pressure drops and holdups for all the flow regimes. A large code incorporating all the features of the model has been programmed and is currently being tested.« less

Productivity depends more on the rate than the frequency of N addition in a temperate grassland.

PubMed

Zhang, Yunhai; Feng, Jinchao; Isbell, Forest; Lü, Xiaotao; Han, Xingguo

2015-07-28

Nitrogen (N) is a key limiting resource for aboveground net primary productivity (ANPP) in diverse terrestrial ecosystems. The relative roles of the rate and frequency (additions yr(-1)) of N application in stimulating ANPP at both the community- and species-levels are largely unknown. By independently manipulating the rate and frequency of N input, with nine rates (from 0 to 50 g N m(-2) year(-1)) crossed with two frequencies (twice year(-1) or monthly) in a temperate steppe of northern China across 2008-2013, we found that N addition increased community ANPP, and had positive, negative, or neutral effects for individual species. There were similar ANPP responses at the community- or species-level when a particular annual amount of N was added either twice year(-1) or monthly. The community ANPP was less sensitive to soil ammonium at lower frequency of N addition. ANPP responses to N addition were positively correlated with annual precipitation. Our results suggest that, over a five-year period, there will be similar ANPP responses to a given annual N input that occurs either frequently in small amounts, as from N deposition, or that occur infrequently in larger amounts, as from application of N fertilizers.

Fungistatic activity of composts with the addition of polymers obtained from thermoplastic corn starch and polyethylene - An innovative cleaner production alternative.

PubMed

Mierzwa-Hersztek, Monika; Gleń-Karolczyk, Katarzyna; Gondek, Krzysztof

2018-04-22

Compost extracts with the addition of polymers obtained from thermoplastic corn starch and polyethylene are novel organic amendments, which can be typically applied to suppress soil-borne diseases. Considering the diversity of biologically active substances, including those growth-promoting and stabilizing various pathogens contained in extracts, composts have a large potential to successfully replace the massively used pesticides. The effect of various concentrations of water compost extracts with the addition of polymers obtained from thermoplastic corn starch and polyethylene on the linear growth, biomass, and sporulation of the following polyphagous fungi was assessed under in situ and in vitro conditions: Fusarium culmorum (W.G. Smith), Fusarium graminearum Schwabe, Sclerotinia sclerotiorum (Lib.) de Bary, Rhizoctonia solani Kühn, Alternaria alternata (Fr.) Keissler. The studies revealed that the fungistatic activity was determined by the kind and concentration of compost extract added to the medium, as well as by the fungus kind. The analyzed compost extracts blocked the linear growth of the tested fungi on average by 22%, biomass increment by 51%, and sporulation by 57%. F. culmorum and S. sclerotiorum proved to be the most sensitive to the tested compost extracts. It was found that the extract from compost with the addition of polymer with the highest share of polyethylene blocked the sporulation of F. culmorum by 87% and F. graminearum by 92%. In turn, composts with the addition of polymers with the highest share of a biocomponent weakened the fungistatic activity of composts. The authors demonstrated that the addition of microbiological inoculum to one of the composts enhanced the fungistatic activity with respect to S. sclerotiorum, F. graminearum, and F. culmorum. The obtained results can be used to better understand the growth-promoting and suppression effects of compost extracts with polymer addition, help to enhance crop production, and constitute a

Keeping Ourselves Well: Strategies for Promoting and Maintaining Counselor Wellness

ERIC Educational Resources Information Center

Cummins, Paige N.; Massey, Linda; Jones, Anita

2007-01-01

This article describes challenges to wellness that counselors face when working with clients. Autobiographical reflections are used to illustrate the personal nature of some of these challenges and how this affects counselor effectiveness and wellness. Additionally, assessment measures and theoretical models for promoting and maintaining wellness…

Solutol and cremophor products as new additives in suppository formulation.

PubMed

Berkó, Szilvia; Regdon, Géza; Erös, István

2002-01-01

Our research has a double purpose. On the one hand, doctors have expressed the need to formulate a rectal suppository dosage form from diuretic ethacrynic acid, which would add to the choice of treatment methods and thereby increase the possibilities of individual cure. On the other hand, the liberation and thereby the bioavailability of poorly-soluble ethacrynic acid needs to be enhanced, and for this purpose solubility-increasing additives new to rectal therapy were used. Solutol HS 15, Cremophor RH 40, and Cremophor RH 60 were used as additives in concentrations of 1, 3, 5, and 10%. The quantity of drug released changed as a function of additive concentration. Depending on the acceptor phase, the best results were achieved with an additive concentration of 1-3%, which is related to the optimal additive quantity accumulated on the boundary surface.

Effect of technological factors on water activity of extruded corn product with an addition of whey proteins.

PubMed

Makowska, Agnieszka; Cais-Sokolińska, Dorota; Lasik, Agata

2014-01-01

The value of water activity in extruded products constitutes a significant indicator of their quality and stability. The state, in which water is found in extruded products, is an indicator of the conducted extrusion process and the used raw material. The aim of the study was to assess water activity in extruded products made from a mixture of com grits with 12.5 and 15.0% moisture contents and different level of addition of whey proteins. It was shown that the degree of mixture moisture content did not have an effect on the value of aw in produced puffs. The greatest difference was recorded when introducing 3% proteins in comparison to aw of puffs produced solely from corn grits. Δaw = 0.023. The greater the content of whey proteins, the lower the aw value. A 3-month storage at a temperature of 18 ±0.5°C influenced aw of snacks produced from a mixture with a higher moisture content.

Hydrogeology and simulation of source areas of water to production wells in a colluvium-mantled carbonate-bedrock aquifer near Shippensburg, Cumberland and Franklin Counties, Pennsylvania

USGS Publications Warehouse

Lindsey, Bruce D.

2005-01-01

This report presents the results of a study by the U.S. Geological Survey in cooperation with the Shippensburg Borough Authority to evaluate the source areas of water to production wells in a colluvium-mantled carbonate-bedrock aquifer in Cumberland and Franklin Counties, Pa. The areal extent of the zone of contribution was simulated for three production wells near Shippensburg, Pa. by use of a ground-water-flow model. A 111-square-mile area was selected as the model area and includes areas of the South Mountain Section and the Great Valley Section of the Valley and Ridge Physiographic Province. Within the model area, the geologic units in the South Mountain area are predominantly metamorphic rocks and the geologic units in the Great Valley are predominantly carbonate rocks. Hydrologic and geologic information were compiled to establish a conceptual model of ground-water flow. Characteristics of aquifer materials were determined, and streamflow and water levels were measured. Streamflow measurements in November 2003 showed all streams lost water as they flowed from South Mountain over the colluvium-mantled carbonate aquifer into the Great Valley. Some streams lost more than 1 cubic foot per second to the aquifer in this area. The Shippensburg Borough Authority owns three production wells in the model area. Two wells, Cu 969 and Fr 823, are currently (2004) used as production wells and produce 500,000 and 800,000 gallons per day, respectively. Well Cu 970 is intended to be brought on line as a production well in the future. Water levels were measured in 43 wells to use for model calibration. Water-level fluctuations and geophysical logs indicated confined conditions in well Cu 970. Ground-water flow was simulated with a model that consisted of two vertical layers, with five zones in each layer. The units were hydrostratigraphic units that initially were based on geologic formations, but boundaries were adjusted during model calibration. Model calibration resulted in

The effects of processing non-timber forest products and trade partnerships on people's well-being and forest conservation in Amazonian societies.

PubMed

Morsello, Carla; Ruiz-Mallén, Isabel; Diaz, Maria Dolores Montoya; Reyes-García, Victoria

2012-01-01

This study evaluated whether processing non-timber forest products (NTFPs) and establishing trade partnerships between forest communities and companies enhance the outcomes of NTFP commercialization. In particular, we evaluated whether product processing, partnerships, or their combination was associated with a number of outcomes related to the well-being of forest inhabitants and forest conservation. We based our analyses on ethnographic and quantitative data (i.e., survey and systematic observations) gathered at seven communities from five societies of the Brazilian and Bolivian Amazon. Our results indicated that product processing and partnerships do not represent a silver bullet able to improve the results of NTFP commercialization in terms of well-being and conservation indicators. Compared with cases without interventions, households adopting partnerships but not product processing were most often associated with improved economic proxies of well-being (total income, NTFP income, food consumption and gender equality in income). In comparison, the combination of product processing and partnerships was associated with similar outcomes. Unexpectedly, product processing alone was associated with negative outcomes in the economic indicators of well-being. All of the investigated strategies were associated with less time spent in social and cultural activities. With respect to forest conservation, the strategies that included a partnership with or without processing produced similar results: while household deforestation tended to decrease, the hunting impact increased. Processing alone was also associated with higher levels of hunting, though it did not reduce deforestation. Our results indicate that establishing partnerships may enhance the outcomes of NTFP trade in terms of the financial outcomes of local communities, but practitioners need to use caution when adopting the processing strategy and they need to evaluate potential negative results for indicators of

The Effects of Processing Non-Timber Forest Products and Trade Partnerships on People's Well-Being and Forest Conservation in Amazonian Societies

PubMed Central

Morsello, Carla; Ruiz-Mallén, Isabel; Diaz, Maria Dolores Montoya; Reyes-García, Victoria

2012-01-01

This study evaluated whether processing non-timber forest products (NTFPs) and establishing trade partnerships between forest communities and companies enhance the outcomes of NTFP commercialization. In particular, we evaluated whether product processing, partnerships, or their combination was associated with a number of outcomes related to the well-being of forest inhabitants and forest conservation. We based our analyses on ethnographic and quantitative data (i.e., survey and systematic observations) gathered at seven communities from five societies of the Brazilian and Bolivian Amazon. Our results indicated that product processing and partnerships do not represent a silver bullet able to improve the results of NTFP commercialization in terms of well-being and conservation indicators. Compared with cases without interventions, households adopting partnerships but not product processing were most often associated with improved economic proxies of well-being (total income, NTFP income, food consumption and gender equality in income). In comparison, the combination of product processing and partnerships was associated with similar outcomes. Unexpectedly, product processing alone was associated with negative outcomes in the economic indicators of well-being. All of the investigated strategies were associated with less time spent in social and cultural activities. With respect to forest conservation, the strategies that included a partnership with or without processing produced similar results: while household deforestation tended to decrease, the hunting impact increased. Processing alone was also associated with higher levels of hunting, though it did not reduce deforestation. Our results indicate that establishing partnerships may enhance the outcomes of NTFP trade in terms of the financial outcomes of local communities, but practitioners need to use caution when adopting the processing strategy and they need to evaluate potential negative results for indicators of

Effects of dietary addition of cellulase and a Saccharomyces cerevisiae fermentation product on nutrient digestibility, rumen fermentation and enteric methane emissions in growing goats.

PubMed

Lu, Qi; Wu, Jian; Wang, Min; Zhou, Chuanshe; Han, Xuefeng; Odongo, Edwin Nicholas; Tan, Zhiliang; Tang, Shaoxun

2016-01-01

This study was designed to assess the effectiveness of dietary cellulase (243 U/g, derived from Neocallimastix patriciarum) and a Saccharomyces cerevisiae fermentation product (yeast product) on ruminal fermentation characteristics, enteric methane (CH4) emissions and methanogenic community in growing goats. The experiment was conducted in a 5 × 5 Latin square design using five Xiangdong black wether goats. The treatments included a Control and two levels of cellulase (0.8 g and 1.6 g/kg dry matter intake (DMI), i.e. 194 U/kg and 389 U/kg DMI, respectively) crossed over with two levels (6 g or 12 g/kg DMI) of the yeast product. There were no significant differences regarding feed intake, apparent digestibility of organic matter, neutral detergent fibre and acid detergent fibre among all the treatments. In comparison with the Control, the ruminal ammonia N concentration was decreased (p = 0.001) by cellulase and yeast product addition. The activities of carboxymethylcellulase and xylanase were decreased after cellulase addition. Moreover, dietary cellulase and yeast product addition led to a significant reduction (p < 0.05) of enteric CH4 emissions although the diversity and copy numbers of methanogens among treatments were not dissimilar. The present results indicate that the combination of cellulase and yeast fermentation product can reduce the production of CH4 energy and mitigate the enteric CH4 emissions to a certain degree.

Addition of Rubber to soil damages the functional diversity of soil.

PubMed

Goswami, Madhurankhi; Bhattacharyya, Purnita; Tribedi, Prosun

2017-07-01

Rubber is a polymer of isoprene, consisting mainly of cis-1,4-polyisoprene units. The unmanageable production and its irresponsible disposal pose severe threats to environmental ecology. Therefore, the current study focuses extensively on the ill-effects of Rubber disposal on soil microbial functional diversity as it reflects the health of ecosystem by acting as a key component in ecosystem productivity. To investigate the effect of Rubber on soil microbial functional diversity, soil samples were collected from landfill sites and three different soil microcosms (Rubber treated, untreated, and sterile soil) were prepared. The soil enzymatic activity was determined by fluorescein diacetate hydrolysis followed by the determination of the microbial metabolic potential and functional diversity by average well color development and Shannon-Weaver index (H), respectively. BiOLOG ECO plates were used for determining the microbial functional diversity of the soil microcosms. Higher heterotrophic microbial count as well as higher soil microbial activity was observed in Rubber untreated soil than Rubber treated soil microcosm. The result indicated that the addition of Rubber to soil reduced soil heterotrophic microbial count and soil microbial activity considerably. Similarly, soil microbial metabolic potential as well as microbial functional diversity of soil had been decreased by the addition of Rubber gloves in it. Variation in soil microbial metabolic spectrum between Rubber treated and untreated microcosm was confirmed by multivariate analysis. Collectively, all the results demonstrated that the addition of Rubber to soil reduced the soil microbial functional diversity considerably. Therefore, it is necessary for the commission of serious steps regarding Rubber disposal and protection of the environment from serious environmental issues.

Development of an Improved Cement for Geothermal Wells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Trabits, George

2015-04-20

After an oil, gas, or geothermal production well has been drilled, the well must be stabilized with a casing (sections of steel pipe that are joined together) in order to prevent the walls of the well from collapsing. The gap between the casing and the walls of the well is filled with cement, which locks the casing into place. The casing and cementing of geothermal wells is complicated by the harsh conditions of high temperature, high pressure, and a chemical environment (brines with high concentrations of carbon dioxide and sulfuric acid) that degrades conventional Portland cement. During the 1990s andmore » early 2000s, the U.S. Department of Energy’s Geothermal Technologies Office (GTO) provided support for the development of fly-ash-modified calcium aluminate phosphate (CaP) cement, which offers improved resistance to degradation compared with conventional cement. However, the use of CaP cements involves some operational constraints that can increase the cost and complexity of well cementing. In some cases, CaP cements are incompatible with chemical additives that are commonly used to adjust cement setting time. Care must also be taken to ensure that CaP cements do not become contaminated with leftover conventional cement in pumping equipment used in conventional well cementing. With assistance from GTO, Trabits Group, LLC has developed a zeolite-containing cement that performs well in harsh geothermal conditions (thermal stability at temperatures of up to 300°C and resistance to carbonation) and is easy to use (can be easily adjusted with additives and eliminates the need to “sterilize” pumping equipment as with CaP cements). This combination of properties reduces the complexity/cost of well cementing, which will help enable the widespread development of geothermal energy in the United States.« less

Food additives

MedlinePlus

... or natural. Natural food additives include: Herbs or spices to add flavor to foods Vinegar for pickling ... Certain colors improve the appearance of foods. Many spices, as well as natural and man-made flavors, ...

77 FR 37659 - Procurement List; Proposed Additions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-22

... additions to the procurement list. SUMMARY: The Committee is proposing to add products and services to the...- 598-5067 and 1670-01-598-5071 to its Procurement List. The Coverage statement associated with this... connection with the products and services proposed for addition to the Procurement List. Comments on this...

Comparison of particle-tracking and lumped-parameter age-distribution models for evaluating vulnerability of production wells to contamination

USGS Publications Warehouse

Eberts, S.M.; Böhlke, J.K.; Kauffman, L.J.; Jurgens, B.C.

2012-01-01

Environmental age tracers have been used in various ways to help assess vulnerability of drinking-water production wells to contamination. The most appropriate approach will depend on the information that is available and that which is desired. To understand how the well will respond to changing nonpoint-source contaminant inputs at the water table, some representation of the distribution of groundwater ages in the well is needed. Such information for production wells is sparse and difficult to obtain, especially in areas lacking detailed field studies. In this study, age distributions derived from detailed groundwater-flow models with advective particle tracking were compared with those generated from lumped-parameter models to examine conditions in which estimates from simpler, less resource-intensive lumped-parameter models could be used in place of estimates from particle-tracking models. In each of four contrasting hydrogeologic settings in the USA, particle-tracking and lumped-parameter models yielded roughly similar age distributions and largely indistinguishable contaminant trends when based on similar conceptual models and calibrated to similar tracer data. Although model calibrations and predictions were variably affected by tracer limitations and conceptual ambiguities, results illustrated the importance of full age distributions, rather than apparent tracer ages or model mean ages, for trend analysis and forecasting.

Biobased lubricant additives

USDA-ARS?s Scientific Manuscript database

Fully biobased lubricants are those formulated using all biobased ingredients, i.e. biobased base oils and biobased additives. Such formulations provide the maximum environmental, safety, and economic benefits expected from a biobased product. Currently, there are a number of biobased base oils that...

Employee wellness program evaluation.

DOT National Transportation Integrated Search

2008-12-01

Well-designed wellness programs can keep healthy employees healthy, support employees with : health risks to improve their health behaviors, and facilitate organizational efforts to achieve : workforce performance goals. : Productivity lost through a...

16 CFR 1102.16 - Additional information.

Code of Federal Regulations, 2012 CFR

2012-01-01

... PUBLICLY AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE Content Requirements § 1102.16 Additional... in the Database any additional information it determines to be in the public interest, consistent...

16 CFR 1102.16 - Additional information.

Code of Federal Regulations, 2014 CFR

2014-01-01

... PUBLICLY AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE Content Requirements § 1102.16 Additional... in the Database any additional information it determines to be in the public interest, consistent...

Rapid detection of the addition of soybean proteins to cheese and other dairy products by reversed-phase perfusion chromatography.

PubMed

García, M C; Marina, M L

2006-04-01

The undeclared addition of soybean proteins to milk products is forbidden and a method is needed for food control and enforcement. This paper reports the development of a chromatographic method for routine analysis enabling the detection of the addition of soybean proteins to dairy products. A perfusion chromatography column and a linear binary gradient of acetonitrile-water-0.1% (v/v) trifluoroacetic acid at a temperature of 60 degrees C were used. A very simple sample treatment consisting of mixing the sample with a suitable solvent (Milli-Q water or bicarbonate buffer (pH=11)) and centrifuging was used. The method enabled the separation of soybean proteins from milk proteins in less than 4 min (at a flow-rate of 3 ml/min). The method has been successfully applied to the detection of soybean proteins in milk, cheese, yogurt, and enteral formula. The correct quantitation of these vegetable proteins has also been possible in milk adulterated at origin with known sources of soybean proteins. The application of the method to samples adulterated at origin also leads to interesting conclusions as to the effect of the processing conditions used for the preparation of each dairy product on the determination of soybean proteins.

Monitoring ground-surface heating during expansion of the Casa Diablo production well field at Mammoth Lakes, California

USGS Publications Warehouse

Bergfeld, D.; Vaughan, R. Greg; Evans, William C.; Olsen, Eric

2015-01-01

The Long Valley hydrothermal system supports geothermal power production from 3 binary plants (Casa Diablo) near the town of Mammoth Lakes, California. Development and growth of thermal ground at sites west of Casa Diablo have created concerns over planned expansion of a new well field and the associated increases in geothermal fluid production. To ensure that all areas of ground heating are identified prior to new geothermal development, we obtained high-resolution aerial thermal infrared imagery across the region. The imagery covers the existing and proposed well fields and part of the town of Mammoth Lakes. Imagery results from a predawn flight on Oct. 9, 2014 readily identified the Shady Rest thermal area (SRST), one of two large areas of ground heating west of Casa Diablo, as well as other known thermal areas smaller in size. Maximum surface temperatures at 3 thermal areas were 26–28 °C. Numerous small areas with ground temperatures >16 °C were also identified and slated for field investigations in summer 2015. Some thermal anomalies in the town of Mammoth Lakes clearly reflect human activity.Previously established projects to monitor impacts from geothermal power production include yearly surveys of soil temperatures and diffuse CO2 emissions at SRST, and less regular surveys to collect samples from fumaroles and gas vents across the region. Soil temperatures at 20 cm depth at SRST are well correlated with diffuse CO2 flux, and both parameters show little variation during the 2011–14 field surveys. Maximum temperatures were between 55–67 °C and associated CO2 discharge was around 12–18 tonnes per day. The carbon isotope composition of CO2 is fairly uniform across the area ranging between –3.7 to –4.4 ‰. The gas composition of the Shady Rest fumarole however has varied with time, and H2S concentrations in the gas have been increasing since 2009.

"Keep a low profile": pesticide residue, additives, and freon use in Australian tobacco manufacturing

PubMed Central

Chapman, S

2003-01-01

Objectives: To review the Australian tobacco industry's knowledge of pesticide residue on Australian tobacco and its policies and practices on resisting calls by tobacco control advocates that consumers should be informed about pesticide residue as well as additives. Methods: Review of previously internal industry documents relevant to pesticides and additives in Australian tobacco located from the Master Settlement Agreement websites. Results: Between 1972 and 1994 Philip Morris Australia was aware that its leaf samples were often contaminated with pesticide residue, sometimes including organochlorine levels described by PM's European laboratories as being "extremely high". Consumers were not advised of the contamination nor products withdrawn. From 1981, the industry also resisted calls to declare fully the extent of use and long term safety data on all additives used in their products. They developed standard public responses that were evasive and misleading and, in 2000, implemented voluntary additive disclosure which allowed the companies to continue to avoid disclosure of any ingredient they deemed to be a trade secret. There was extensive use of ozone depleting freon in Australian tobacco manufacturing. Again, the industry kept this information away from consumers. Conclusions: Australian smokers are unable to make informed decisions about smoking because pesticide and additive disclosure remains voluntary. The Australian government should regulate tobacco to require full disclosure including information on the likely health consequences of inhaling pesticide and additive pyrolysis products. PMID:14645948

An improved process of isomaltooligosaccharide production in kimchi involving the addition of a Leuconostoc starter and sugars.

PubMed

Cho, Seung Kee; Eom, Hyun-Ju; Moon, Jin Seok; Lim, Sae-Bom; Kim, Yong Kook; Lee, Ki Won; Han, Nam Soo

2014-01-17

Isomaltooligosaccharides (IMOs) are α-(1→6)-linked oligodextrans that show a prebiotic effect on Bifidobacterium spp. This study sought to improve IMO synthesis during lactate fermentation in kimchi by inoculating the kimchi fermentation mix with a starter and sugars; the psychrotrophic Leuconostoc citreum KACC 91035 strain with high dextransucrase activity was used as a starter and sucrose (58 mM) and maltose (56 mM) were added as the donor and acceptor for the glucose-transferring reaction of the dextransucrase, respectively. With the addition of both the starter and the sugars and incubation at 10°C, IMOs were produced in kimchi after 3d. Without the starter, the IMO production rate and maximal concentration in kimchi were 15.05 mM/d and 75.27 mM, respectively, whereas with the starter, the rate and concentration increased to 22.04 mM/d and 110.19 mM, respectively. In addition, the sucrose-maltose mix gave an appropriate level of sweetness by releasing fructose and prevented unfavorable polymer synthesis by IMO production. This result suggests that lactic acid bacteria expressing a highly active glycosyltransferase can be used for the synthesis of beneficial oligosaccharides in various fermented foods. © 2013.

Response of AM fungi spore population to elevated temperature and nitrogen addition and their influence on the plant community composition and productivity

NASA Astrophysics Data System (ADS)

Zhang, Tao; Yang, Xue; Guo, Rui; Guo, Jixun

2016-04-01

To examine the influence of elevated temperature and nitrogen (N) addition on species composition and development of arbuscular mycorrhizal fungi (AMF) and the effect of AMF on plant community structure and aboveground productivity, we conducted a 5-year field experiment in a temperate meadow in northeast China and a subsequent greenhouse experiment. In the field experiment, N addition reduced spore population diversity and richness of AMF and suppressed the spore density and the hyphal length density (HLD). Elevated temperature decreased spore density and diameter and increased the HLD, but did not affect AMF spore population composition. In the greenhouse experiment, AMF altered plant community composition and increased total aboveground biomass in both elevated temperature and N addition treatments; additionally, AMF also increased the relative abundance and aboveground biomass of the grasses Leymus chinensis (Poaceae) and Setaria viridis (Gramineae) and significantly reduced the relative abundance and aboveground biomass of the Suaeda corniculata (Chenopodiaceae). Although elevated temperature and N addition can affect species composition or suppress the development of AMF, AMF are likely to play a vital role in increasing plant diversity and productivity. Notably, AMF might reduce the threat of climate change induced degradation of temperate meadow ecosystems.

Response of AM fungi spore population to elevated temperature and nitrogen addition and their influence on the plant community composition and productivity

PubMed Central

Zhang, Tao; Yang, Xue; Guo, Rui; Guo, Jixun

2016-01-01

To examine the influence of elevated temperature and nitrogen (N) addition on species composition and development of arbuscular mycorrhizal fungi (AMF) and the effect of AMF on plant community structure and aboveground productivity, we conducted a 5-year field experiment in a temperate meadow in northeast China and a subsequent greenhouse experiment. In the field experiment, N addition reduced spore population diversity and richness of AMF and suppressed the spore density and the hyphal length density (HLD). Elevated temperature decreased spore density and diameter and increased the HLD, but did not affect AMF spore population composition. In the greenhouse experiment, AMF altered plant community composition and increased total aboveground biomass in both elevated temperature and N addition treatments; additionally, AMF also increased the relative abundance and aboveground biomass of the grasses Leymus chinensis (Poaceae) and Setaria viridis (Gramineae) and significantly reduced the relative abundance and aboveground biomass of the Suaeda corniculata (Chenopodiaceae). Although elevated temperature and N addition can affect species composition or suppress the development of AMF, AMF are likely to play a vital role in increasing plant diversity and productivity. Notably, AMF might reduce the threat of climate change induced degradation of temperate meadow ecosystems. PMID:27098761

27 CFR 18.27 - Additional requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Additional requirements. 18.27 Section 18.27 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS PRODUCTION OF VOLATILE FRUIT-FLAVOR CONCENTRATE Qualification Application...

27 CFR 18.27 - Additional requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Additional requirements. 18.27 Section 18.27 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS PRODUCTION OF VOLATILE FRUIT-FLAVOR CONCENTRATE Qualification Application...

27 CFR 18.27 - Additional requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Additional requirements. 18.27 Section 18.27 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL PRODUCTION OF VOLATILE FRUIT-FLAVOR CONCENTRATE Qualification Application...

27 CFR 18.27 - Additional requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Additional requirements. 18.27 Section 18.27 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL PRODUCTION OF VOLATILE FRUIT-FLAVOR CONCENTRATE Qualification Application...

27 CFR 18.27 - Additional requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Additional requirements. 18.27 Section 18.27 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS PRODUCTION OF VOLATILE FRUIT-FLAVOR CONCENTRATE Qualification Application...

Groundwater quality from private domestic water-supply wells in the vicinity of petroleum production in southwestern Indiana

USGS Publications Warehouse

Risch, Martin R.; Silcox, Cheryl A.

2016-06-02

The U.S. Geological Survey provided technical support to the Agency for Toxic Substances and Disease Registry for site selection and sample collection and analysis in a 2012 investigation of groundwater quality from 29 private domestic water-supply wells in the vicinity of petroleum production in southwestern Indiana. Petroleum hydrocarbons, oil and grease, aromatic volatile organic compounds, methane concentrations greater than 8,800 micrograms per liter, chloride concentrations greater than 250 milligrams per liter, and gross alpha radioactivity greater than 15 picocuries per liter were reported in the analysis of groundwater samples from 11 wells.

Effects of Phytoestrogen Extracts Isolated from Elder Flower on Hormone Production and Receptor Expression of Trophoblast Tumor Cells JEG-3 and BeWo, as well as MCF7 Breast Cancer Cells

PubMed Central

Schröder, Lennard; Richter, Dagmar Ulrike; Piechulla, Birgit; Chrobak, Mareike; Kuhn, Christina; Schulze, Sandra; Abarzua, Sybille; Jeschke, Udo; Weissenbacher, Tobias

2016-01-01

Herein we investigated the effect of elderflower extracts (EFE) and of enterolactone/enterodiol on hormone production and proliferation of trophoblast tumor cell lines JEG-3 and BeWo, as well as MCF7 breast cancer cells. The EFE was analyzed by mass spectrometry. Cells were incubated with various concentrations of EFE. Untreated cells served as controls. Supernatants were tested for estradiol production with an ELISA method. Furthermore, the effect of the EFE on ERα/ERβ/PR expression was assessed by immunocytochemistry. EFE contains a substantial amount of lignans. Estradiol production was inhibited in all cells in a concentration-dependent manner. EFE upregulated ERα in JEG-3 cell lines. In MCF7 cells, a significant ERα downregulation and PR upregulation were observed. The control substances enterolactone and enterodiol in contrast inhibited the expression of both ER and of PR in MCF7 cells. In addition, the production of estradiol was upregulated in BeWo and MCF7 cells in a concentration dependent manner. The downregulating effect of EFE on ERα expression and the upregulation of the PR expression in MFC-7 cells are promising results. Therefore, additional unknown substances might be responsible for ERα downregulation and PR upregulation. These findings suggest potential use of EFE in breast cancer prevention and/or treatment and warrant further investigation. PMID:27740591

Well sealing via thermite reactions

DOEpatents

Lowry, William Edward; Dunn, Sandra Dalvit

2016-11-15

A platform is formed in a well below a target plug zone by lowering a thermite reaction charge into the well and igniting it, whereby the products of the reaction are allowed to cool and expand to form a platform or support in the well. A main thermite reaction charge is placed above the platform and ignited to form a main sealing plug for the well. In some embodiments an upper plug is formed by igniting an upper thermite reaction charge above the main thermite reaction charge. The upper plug confines the products of ignition of the main thermite reaction charge.

Well development by jetting using coiled tubing and simultaneous pumping.

PubMed

Rosberg, Jan-Erik; Bjelm, Leif

2009-01-01

During flow testing of a deep, 1927-m, gravel packed screen completed well, it became apparent that well development was needed to increase productivity. A hydrojetting system using coiled tubing in combination with simultaneous pumping was developed and tested and found to be successful. To verify whether the jetting improved the well, the results of a pumping test conducted before and after the jetting operation are compared. In addition, flowmeter logging and hydraulic properties obtained from pumping tests conducted during the jetting operation were also used to verify the improvements. Hydrojetting in combination with simultaneous pumping proved to be an effective cleaning method. After 100 min of pumping, around 110 m less drawdown and 15 L/s higher average flow rate were obtained compared to the values before the jetting operation. The skin factor was positive before the jetting operation and negative thereafter, thus providing additional evidence of improvements of the well. The flowmeter data also confirmed the improvements and were valuable in optimizing the jetting operation. It was also found, from the short-term pumping tests conducted during the jetting operation, that the Hantush-Jacob method for leaky confined aquifers is a valuable indicator of the well development. The combination of methods used for the well development in this case can easily be applied on other deep well projects to obtain a controlled and time-efficient well development. Copyright © 2009 The Author(s). Journal Compilation © 2009 National Ground Water Association.

Influence of the metal addition for biohydrogen production from the conversion of palm oil mill effluent (POME) by anaerobic process

NASA Astrophysics Data System (ADS)

Gumilar, Andri; Syafila, Mindriany; Handajani, Marisa

2017-11-01

Biohydrogen is one of the main alternative fuels promising for the future. Bioconversion of the wastewater with the high concentration of organic using biological processes or microorganism by anaerobic processes can produce biogas which can be used as fuel instead of fossil fuels. In this study, palm oil mill effluent (POME) with the concentration of COD is 24,500 mg/L has been used as a substrate. The aim of this study was to determine the effect of metal addition for the formation of biohydrogen. Circulating bed reactor (CBR) is used with the flushing N2 1L/min for 24 hr and continued operates for 72 hr by internal biogas. The additional variation concentration of Fe(II) ion are 0.5; 1.0 and 2.5 mg/L, and Mg(II) are 0.5 and 1.5 mg/L were added by combination. The results showed that the combination of Fe(II) 1.0 mg/L and Mg(II) 1.5 mg/L produced the highest biohydrogen production is 17.12 %v/v and the rate of biohydrogen production is 0.010-0.233 % v/v /hr. Another combination of Fe(II) and Mg(II) provide results for the biohydrogen production is 10.46-16.37 %v/v with the highest rate of biohydrogen production is 0.008-0.278 %v/v/hr.

Research of cement mixtures with additions of industrial by-products

NASA Astrophysics Data System (ADS)

Papesch, R.; Klus, L.; Svoboda, J.; Zajac, R.

2017-10-01

The main goal of the article is the comparison of the possible use of secondary energy products. Used fly ashes, respectively steel dusts in cement mixes derive from production in Moravian-Silesian Region. The research focused on their influence on the chemical and physico-mechanical characteristics of the fresh and solid mixture. The aim was to find suitable formulations for grouting works, highway construction possibly rehabilitation of underground cavities created by mining activities. The introduction is mentioned the history of waste utilization up to current use as a product and the overall state of the problem. The conclusion is an evaluation of possible use in practice, including recommendations to carry out further tests.

77 FR 12816 - Procurement List; Additions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-02

... Procurement List. SUMMARY: This action adds products to the Procurement List that will be furnished by... capability of qualified nonprofit agencies to provide the products and impact of the additions on the current or most recent contractors, the Committee has determined that the products listed below are suitable...

77 FR 40343 - Procurement List; Additions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-09

... Procurement List. SUMMARY: This action adds products and services to the Procurement List that will be... concerning capability of qualified nonprofit agencies to provide the products and services and impact of the additions on the current or most recent contractors, the Committee has determined that products and services...

Addition of genes for cellobiase and pectinolytic activity in Escherichia coli for fuel ethanol production from pectin-rich lignocellulosic biomass.

PubMed

Edwards, Meredith C; Henriksen, Emily Decrescenzo; Yomano, Lorraine P; Gardner, Brian C; Sharma, Lekh N; Ingram, Lonnie O; Doran Peterson, Joy

2011-08-01

Ethanologenic Escherichia coli strain KO11 was sequentially engineered to contain the Klebsiella oxytoca cellobiose phosphotransferase genes (casAB) as well as a pectate lyase (pelE) from Erwinia chrysanthemi, yielding strains LY40A (casAB) and JP07 (casAB pelE), respectively. To obtain an effective secretion of PelE, the Sec-dependent pathway out genes from E. chrysanthemi were provided on a cosmid to strain JP07 to construct strain JP07C. Finally, oligogalacturonide lyase (ogl) from E. chrysanthemi was added to produce strain JP08C. E. coli strains LY40A, JP07, JP07C, and JP08C possessed significant cellobiase activity in cell lysates, while only strains JP07C and JP08C demonstrated extracellular pectate lyase activity. Fermentations conducted by using a mixture of pure sugars representative of the composition of sugar beet pulp (SBP) showed that strains LY40A, JP07, JP07C, and JP08C were able to ferment cellobiose, resulting in increased ethanol production from 15 to 45% in comparison to that of KO11. Fermentations with SBP at very low fungal enzyme loads during saccharification revealed significantly higher levels of ethanol production for LY40A, JP07C, and JP08C than for KO11. JP07C ethanol yields were not considerably higher than those of LY40A; however, oligogalacturonide polymerization studies showed an increased breakdown of biomass to small-chain (degree of polymerization, ≤6) oligogalacturonides. JP08C achieved a further breakdown of polygalacturonate to monomeric sugars, resulting in a 164% increase in ethanol yields compared to those of KO11. The addition of commercial pectin methylesterase (PME) further increased JP08C ethanol production compared to that of LY40A by demethylating the pectin for enzymatic attack by pectin-degrading enzymes.

Addition of Genes for Cellobiase and Pectinolytic Activity in Escherichia coli for Fuel Ethanol Production from Pectin-Rich Lignocellulosic Biomass▿

PubMed Central

Edwards, Meredith C.; Henriksen, Emily DeCrescenzo; Yomano, Lorraine P.; Gardner, Brian C.; Sharma, Lekh N.; Ingram, Lonnie O.; Doran Peterson, Joy

2011-01-01

Ethanologenic Escherichia coli strain KO11 was sequentially engineered to contain the Klebsiella oxytoca cellobiose phosphotransferase genes (casAB) as well as a pectate lyase (pelE) from Erwinia chrysanthemi, yielding strains LY40A (casAB) and JP07 (casAB pelE), respectively. To obtain an effective secretion of PelE, the Sec-dependent pathway out genes from E. chrysanthemi were provided on a cosmid to strain JP07 to construct strain JP07C. Finally, oligogalacturonide lyase (ogl) from E. chrysanthemi was added to produce strain JP08C. E. coli strains LY40A, JP07, JP07C, and JP08C possessed significant cellobiase activity in cell lysates, while only strains JP07C and JP08C demonstrated extracellular pectate lyase activity. Fermentations conducted by using a mixture of pure sugars representative of the composition of sugar beet pulp (SBP) showed that strains LY40A, JP07, JP07C, and JP08C were able to ferment cellobiose, resulting in increased ethanol production from 15 to 45% in comparison to that of KO11. Fermentations with SBP at very low fungal enzyme loads during saccharification revealed significantly higher levels of ethanol production for LY40A, JP07C, and JP08C than for KO11. JP07C ethanol yields were not considerably higher than those of LY40A; however, oligogalacturonide polymerization studies showed an increased breakdown of biomass to small-chain (degree of polymerization, ≤6) oligogalacturonides. JP08C achieved a further breakdown of polygalacturonate to monomeric sugars, resulting in a 164% increase in ethanol yields compared to those of KO11. The addition of commercial pectin methylesterase (PME) further increased JP08C ethanol production compared to that of LY40A by demethylating the pectin for enzymatic attack by pectin-degrading enzymes. PMID:21666025

SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scott Reeves

2003-03-01

Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Prepared various materials to describe the project for promotional purposes and to attract potential industry partners. Materials included slides for DOE's displays at the SPE Eastern Regional and Annual Technical

Generalized Heisenberg Algebras, SUSYQM and Degeneracies: Infinite Well and Morse Potential

NASA Astrophysics Data System (ADS)

Hussin, Véronique; Marquette, Ian

2011-03-01

We consider classical and quantum one and two-dimensional systems with ladder operators that satisfy generalized Heisenberg algebras. In the classical case, this construction is related to the existence of closed trajectories. In particular, we apply these results to the infinite well and Morse potentials. We discuss how the degeneracies of the permutation symmetry of quantum two-dimensional systems can be explained using products of ladder operators. These products satisfy interesting commutation relations. The two-dimensional Morse quantum system is also related to a generalized two-dimensional Morse supersymmetric model. Arithmetical or accidental degeneracies of such system are shown to be associated to additional supersymmetry.

Study of gas production from shale reservoirs with multi-stage hydraulic fracturing horizontal well considering multiple transport mechanisms.

PubMed

Guo, Chaohua; Wei, Mingzhen; Liu, Hong

2018-01-01

Development of unconventional shale gas reservoirs (SGRs) has been boosted by the advancements in two key technologies: horizontal drilling and multi-stage hydraulic fracturing. A large number of multi-stage fractured horizontal wells (MsFHW) have been drilled to enhance reservoir production performance. Gas flow in SGRs is a multi-mechanism process, including: desorption, diffusion, and non-Darcy flow. The productivity of the SGRs with MsFHW is influenced by both reservoir conditions and hydraulic fracture properties. However, rare simulation work has been conducted for multi-stage hydraulic fractured SGRs. Most of them use well testing methods, which have too many unrealistic simplifications and assumptions. Also, no systematical work has been conducted considering all reasonable transport mechanisms. And there are very few works on sensitivity studies of uncertain parameters using real parameter ranges. Hence, a detailed and systematic study of reservoir simulation with MsFHW is still necessary. In this paper, a dual porosity model was constructed to estimate the effect of parameters on shale gas production with MsFHW. The simulation model was verified with the available field data from the Barnett Shale. The following mechanisms have been considered in this model: viscous flow, slip flow, Knudsen diffusion, and gas desorption. Langmuir isotherm was used to simulate the gas desorption process. Sensitivity analysis on SGRs' production performance with MsFHW has been conducted. Parameters influencing shale gas production were classified into two categories: reservoir parameters including matrix permeability, matrix porosity; and hydraulic fracture parameters including hydraulic fracture spacing, and fracture half-length. Typical ranges of matrix parameters have been reviewed. Sensitivity analysis have been conducted to analyze the effect of the above factors on the production performance of SGRs. Through comparison, it can be found that hydraulic fracture

Study of gas production from shale reservoirs with multi-stage hydraulic fracturing horizontal well considering multiple transport mechanisms

PubMed Central

Wei, Mingzhen; Liu, Hong

2018-01-01

Development of unconventional shale gas reservoirs (SGRs) has been boosted by the advancements in two key technologies: horizontal drilling and multi-stage hydraulic fracturing. A large number of multi-stage fractured horizontal wells (MsFHW) have been drilled to enhance reservoir production performance. Gas flow in SGRs is a multi-mechanism process, including: desorption, diffusion, and non-Darcy flow. The productivity of the SGRs with MsFHW is influenced by both reservoir conditions and hydraulic fracture properties. However, rare simulation work has been conducted for multi-stage hydraulic fractured SGRs. Most of them use well testing methods, which have too many unrealistic simplifications and assumptions. Also, no systematical work has been conducted considering all reasonable transport mechanisms. And there are very few works on sensitivity studies of uncertain parameters using real parameter ranges. Hence, a detailed and systematic study of reservoir simulation with MsFHW is still necessary. In this paper, a dual porosity model was constructed to estimate the effect of parameters on shale gas production with MsFHW. The simulation model was verified with the available field data from the Barnett Shale. The following mechanisms have been considered in this model: viscous flow, slip flow, Knudsen diffusion, and gas desorption. Langmuir isotherm was used to simulate the gas desorption process. Sensitivity analysis on SGRs’ production performance with MsFHW has been conducted. Parameters influencing shale gas production were classified into two categories: reservoir parameters including matrix permeability, matrix porosity; and hydraulic fracture parameters including hydraulic fracture spacing, and fracture half-length. Typical ranges of matrix parameters have been reviewed. Sensitivity analysis have been conducted to analyze the effect of the above factors on the production performance of SGRs. Through comparison, it can be found that hydraulic fracture

Effects on well-being of investing in cleaner air in India.

PubMed

Sanderson, Warren; Striessnig, Erich; Schöpp, Wolfgang; Amann, Markus

2013-01-01

Over the past decade, India has experienced rapid economic growth along with increases in levels of air pollution. Our goal is to examine how alternative policies for air pollution abatement affect well-being there. In particular, we estimate the effects of policies to reduce the levels of ambient fine particulates (PM2.5), which are especially harmful to human health, on well-being, quantified using the United Nations' human development index (HDI). Two of the three dimensions of this index are based on gross domestic product (GDP) per capita and life expectancy. Our approach allows reductions in PM2.5 to affect both of them. In particular, economic growth is affected negatively through the costs of the additional pollution control measures and positively through the increased productivity of the population. We consider three scenarios of PM2.5 abatement, corresponding to no further control, current Indian legislation, and current European legislation. The overall effect in both control scenarios is that growth in GDP is virtually unaffected relative to the case of no further controls, life expectancy is higher, and well-being, as measured by the HDI, is improved. In India, air pollution abatement investments clearly improve well-being.

75 FR 14576 - Procurement List Additions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-26

... Inspection Service, Minneapolis, MN. M.R. Laundry Products NSN: MR 1103--Heavy Duty Laundry Bag. NSN: MR 1104... procurement list. SUMMARY: This action adds to the Procurement List products and services to be furnished by... products and services and impact of the additions on the current or most recent contractors, the Committee...

Leaching of additives from construction materials to urban storm water runoff.

PubMed

Burkhardt, M; Zuleeg, S; Vonbank, R; Schmid, P; Hean, S; Lamani, X; Bester, K; Boller, M

2011-01-01

Urban water management requires further clarification about pollutants in storm water. Little is known about the release of organic additives used in construction materials and the impact of these compounds to storm water runoff. We investigated sources and pathways of additives used in construction materials, i.e., biocides in facades' render as well as root protection products in bitumen membranes for rooftops. Under wet-weather conditions, the concentrations of diuron, terbutryn, carbendazim, irgarol 1051 (all from facades) and mecoprop in storm water and receiving water exceeded the predicted no-effect concentrations values and the Swiss water quality standard of 0.1 microg/L. Under laboratory conditions maximum concentrations of additives were in the range of a few milligrams and a few hundred micrograms per litre in runoff of facades and bitumen membranes. Runoff from aged materials shows approximately one to two orders of magnitude lower concentrations. Concentrations decreased also during individual runoff events. In storm water and receiving water the occurrence of additives did not follow the typical first flush model. This can be explained by the release lasting over the time of rainfall and the complexity of the drainage network. Beside the amounts used, the impact of construction materials containing hazardous additives on water quality is related clearly to the age of the buildings and the separated sewer network. The development of improved products regarding release of hazardous additives is the most efficient way of reducing the pollutant load from construction materials in storm water runoff.

Production of Enzymes from Marine Actinobacteria.

PubMed

Zhao, X Q; Xu, X N; Chen, L Y

Marine actinobacteria are well recognized for their capabilities to produce valuable natural products, which have great potential for applications in medical, agricultural, and fine chemical industries. In addition to producing unique enzymes responsible for biosynthesis of natural products, many marine actinobacteria also produce hydrolytic enzymes which are able to degrade various biopolymers, such as cellulose, xylan, and chitin. These enzymes are important to produce biofuels and biochemicals of interest from renewable biomass. In this chapter, the recent reports of novel enzymes produced by marine actinobacteria are reviewed, and advanced technologies that can be applied to search for novel marine enzymes as well as for improved enzyme production by marine actinobacteria are summarized, which include ribosome engineering, genome mining, as well as synthetic biology studies. © 2016 Elsevier Inc. All rights reserved.

High production of D-tagatose by the addition of boric acid.

PubMed

Lim, Byung-Chul; Kim, Hye-Jung; Oh, Deok-Kun

2007-01-01

An L-arabinose isomerase mutant enzyme from Geobacillus thermodenitrificans was used to catalyze the isomerization of D-galactose to D-tagatose with boric acid. Maximum production of D-tagatose occurred at pH 8.5-9.0, 60 degrees C, and 0.4 molar ratio of boric acid to D-galactose, and the production increased with increasing enzyme concentration. Under the optimum conditions, the enzyme (10.8 units/mL) converted 300 g/L D-galactose to 230 g/L D-tagatose for 20 h with a yield of 77% (w/w); the production and conversion yield with boric acid were 1.5-fold and 24% higher than without boric acid, respectively. In 24 h, the enzyme produced 370 g/L D-tagatose from 500 g/L D-galactose with boric acid, corresponding to a conversion yield of 74% (w/w) and a production rate of 15.4 g/L.h. The production and yield of D-tagatose obtained in this study are unprecedented.

Wellness-Promoting Practices Through Girl Scouts: A Pragmatic Superiority Randomized Controlled Trial With Additional Dissemination.

PubMed

Cull, Brooke J; Dzewaltowski, David A; Guagliano, Justin M; Rosenkranz, Sara K; Knutson, Cassandra K; Rosenkranz, Richard R

2018-01-01

To evaluate the effectiveness of in-person versus online Girl Scout leader wellness training for implementation of wellness-promoting practices during troop meetings (phase I) and to assess training adoption and current practices across the council (phase II). Pragmatic superiority trial (phase 1) followed by serial cross-sectional study (phase II). Girl Scout troop meetings in Northeast Kansas. Eighteen troop leaders from 3 counties (phase 1); 113 troop leaders from 7 counties (phase II). Phase I: Troop leaders attended 2 wellness training sessions (first in groups, second individually), wherein leaders set wellness-promoting practice implementation goals, self-monitored progress, and received guidance and resources for implementation. Leaders received the intervention in person or online. Phase I: At baseline and postintervention, leaders completed a wellness-promoting practice implementation questionnaire assessing practices during troop meetings (max score = 11). Phase II: Leaders completed a survey about typical troop practices and interest in further training. Phase I: Generalized linear mixed modeling. Phase I: In-person training increased wellness-promoting practice implementation more than online training (in person = 2.1 ± 1.8; online = 0.2 ± 1.2; P = .022). Phase II: Fifty-six percent of leaders adopted the training. For 8 of 11 wellness categories, greater than 50% of leaders employed wellness-promoting practices. In-person training was superior to online training for improvements in wellness-promoting practices. Wellness training was adopted by the majority of leaders across the council.

Effects of trace element addition on process stability during anaerobic co-digestion of OFMSW and slaughterhouse waste.

PubMed

Moestedt, J; Nordell, E; Shakeri Yekta, S; Lundgren, J; Martí, M; Sundberg, C; Ejlertsson, J; Svensson, B H; Björn, A

2016-01-01

This study used semi-continuous laboratory scale biogas reactors to simulate the effects of trace-element addition in different combinations, while degrading the organic fraction of municipal solid waste and slaughterhouse waste. The results show that the combined addition of Fe, Co and Ni was superior to the addition of only Fe, Fe and Co or Fe and Ni. However, the addition of only Fe resulted in a more stable process than the combined addition of Fe and Co, perhaps indicating a too efficient acidogenesis and/or homoacetogenesis in relation to a Ni-deprived methanogenic population. The results were observed in terms of higher biogas production (+9%), biogas production rates (+35%) and reduced VFA concentration for combined addition compared to only Fe and Ni. The higher stability was supported by observations of differences in viscosity, intraday VFA- and biogas kinetics as well as by the 16S rRNA gene and 16S rRNA of the methanogens. Copyright © 2015 Elsevier Ltd. All rights reserved.

Volatile organic compounds at oil and natural gas production well pads in Colorado and Texas using passive samplers

EPA Science Inventory

A pilot study was conducted in application of the U.S. Environmental Protection Agency (EPA) Methods 325A/B variant for monitoring volatile organic compounds (VOCs) near two oil and natural gas (ONG) production well pads in the Texas Barnett Shale formation and Colorado Denver&nd...

SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scott Reeves

2003-08-01

Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin of economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Compiled information and results of field activities that Oneok has conducted in relation to the project. Field activities have included performing six pressure transient tests, and implementing six workovers, four of which were

Atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry of friction modifier additives analyzed directly from base oil solutions.

PubMed

Widder, Lukas; Brennerb, Josef; Huttera, Herbert

2014-01-01

To develop new products and to apply measures of quality control quick and simple accessibility of additive composition in automo- tive lubrication is important. The aim of this study was to investigate the possibility of analyzing organic friction modifier additives by means of atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry [AP-MALDI-MS] from lubricant solu- tions without the use of additional separation techniques. Analyses of selected friction modifier ethoxylated tallow amines and oleic acid amide were compared using two ionization methods, positive-ion electrospray ionization (ESI) and AP-MALDI, using a LTQ Orbitrap mass spectrometer. Pure additives were characterized from solvent solutions, as well as from synthetic and mineral base oil mixtures. Detected ions of pure additive samples consisted mainly of [M + H]+, but also alkaLi metal adducts [M + Na]+ and [M + K]+ could be seen. Characterizations of blends of both friction modifiers from the base oil mixtures were carried out as well and showed significant inten- sities for several additive peaks. Thus, this work shows a method to directly analyze friction modifier additives used in the automotive industry from an oil blend via the use of AP-MALDI without any further separation steps. The method presented will further simplify the acquisition of data on lubricant composition and additives. Furthermore, it allows the perspective of analyzing additive reaction products directly from formulated oil blends.

Enhanced Production of Green Tide Algal Biomass through Additional Carbon Supply

PubMed Central

de Paula Silva, Pedro H.; Paul, Nicholas A.; de Nys, Rocky; Mata, Leonardo

2013-01-01

Intensive algal cultivation usually requires a high flux of dissolved inorganic carbon (Ci) to support productivity, particularly for high density algal cultures. Carbon dioxide (CO2) enrichment can be used to overcome Ci limitation and enhance productivity of algae in intensive culture, however, it is unclear whether algal species with the ability to utilise bicarbonate (HCO3 −) as a carbon source for photosynthesis will benefit from CO2 enrichment. This study quantified the HCO3 − affinity of three green tide algal species, Cladophora coelothrix, Cladophora patentiramea and Chaetomorpha linum, targeted for biomass and bioenergy production. Subsequently, we quantified productivity and carbon, nitrogen and ash content in response to CO2 enrichment. All three species had similar high pH compensation points (9.7–9.9), and grew at similar rates up to pH 9, demonstrating HCO3 − utilization. Algal cultures enriched with CO2 as a carbon source had 30% more total Ci available, supplying twenty five times more CO2 than the control. This higher Ci significantly enhanced the productivity of Cladophora coelothrix (26%), Chaetomorpha linum (24%) and to a lesser extent for Cladophora patentiramea (11%), compared to controls. We demonstrated that supplying carbon as CO2 can enhance the productivity of targeted green tide algal species under intensive culture, despite their clear ability to utilise HCO3 −. PMID:24324672

Enhanced production of green tide algal biomass through additional carbon supply.

PubMed

de Paula Silva, Pedro H; Paul, Nicholas A; de Nys, Rocky; Mata, Leonardo

2013-01-01

Intensive algal cultivation usually requires a high flux of dissolved inorganic carbon (Ci) to support productivity, particularly for high density algal cultures. Carbon dioxide (CO2) enrichment can be used to overcome Ci limitation and enhance productivity of algae in intensive culture, however, it is unclear whether algal species with the ability to utilise bicarbonate (HCO3 (-)) as a carbon source for photosynthesis will benefit from CO2 enrichment. This study quantified the HCO3 (-) affinity of three green tide algal species, Cladophora coelothrix, Cladophora patentiramea and Chaetomorpha linum, targeted for biomass and bioenergy production. Subsequently, we quantified productivity and carbon, nitrogen and ash content in response to CO2 enrichment. All three species had similar high pH compensation points (9.7-9.9), and grew at similar rates up to pH 9, demonstrating HCO3 (-) utilization. Algal cultures enriched with CO2 as a carbon source had 30% more total Ci available, supplying twenty five times more CO2 than the control. This higher Ci significantly enhanced the productivity of Cladophora coelothrix (26%), Chaetomorpha linum (24%) and to a lesser extent for Cladophora patentiramea (11%), compared to controls. We demonstrated that supplying carbon as CO2 can enhance the productivity of targeted green tide algal species under intensive culture, despite their clear ability to utilise HCO3 (-).

Workers' Well-Being and Productivity: The Role of Bargaining.

ERIC Educational Resources Information Center

Mayer, Jean

1983-01-01

Bargaining that makes available facilities for satisfaction of workers' basic needs can contribute to increased productivity, which in turn enhances competitiveness. Such bargaining can be an effective means of extending and reinforcing national economic planning. (SK)

Drilling of a deviated well: E. C. Newell 10056-D Meigs County, Ohio

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rodgers, J.A.

1982-09-30

The Department of Energy's (DOE) Eastern Gas Shales Program (EGSP) has focused primarily on the resource characterization of the Devonian shales in the Appalachian, Michigan and Illinois Basins, where the collective volume of gas in place is estimated to be on the order of 280 Tcf. From an early assessment of the petrophysical properties of these shales, attention now has turned to an understanding of the mechanisms controlling production of this unconventional-gas source. However, present knowledge of the production history of the Devonian shales is inadequate for an accurate estimation of the gas reserves, the optimum well spacing for gasmore » extraction, and the preferred stimulation techniques to be used. As part of this program, a Deviated Well Test was designed to evaluate the spacing of natural fractures in the Devonian shale in Meigs County, Ohio as a follow-on test to further define shale production characteristics and to assess the benefit of additional section gained by drilling through the producing interval at the approximate angle for dip of 60/sup 0/ from vertical. The Columbia Gas Transmission Company, E.C. Newell 10056-D well, on the same site as a previous Off-Set Well Test, was selected for this investigation. This report summarizes drilling operations on this Deviated Well Test.« less

9 CFR 392.9 - Availability of additional guidance.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Availability of additional guidance. 392.9 Section 392.9 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOOD SAFETY AND INSPECTION SERVICE ADMINISTRATIVE PROVISIONS PETITIONS FOR RULEMAKING § 392.9 Availability of additional guidance....

9 CFR 392.9 - Availability of additional guidance.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Availability of additional guidance. 392.9 Section 392.9 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOOD SAFETY AND INSPECTION SERVICE ADMINISTRATIVE PROVISIONS PETITIONS FOR RULEMAKING § 392.9 Availability of additional guidance....

9 CFR 392.9 - Availability of additional guidance.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Availability of additional guidance. 392.9 Section 392.9 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOOD SAFETY AND INSPECTION SERVICE ADMINISTRATIVE PROVISIONS PETITIONS FOR RULEMAKING § 392.9 Availability of additional guidance....

9 CFR 392.9 - Availability of additional guidance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Availability of additional guidance. 392.9 Section 392.9 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOOD SAFETY AND INSPECTION SERVICE ADMINISTRATIVE PROVISIONS PETITIONS FOR RULEMAKING § 392.9 Availability of additional guidance....

Scalable 96-well Plate Based iPSC Culture and Production Using a Robotic Liquid Handling System.

PubMed

Conway, Michael K; Gerger, Michael J; Balay, Erin E; O'Connell, Rachel; Hanson, Seth; Daily, Neil J; Wakatsuki, Tetsuro

2015-05-14

Continued advancement in pluripotent stem cell culture is closing the gap between bench and bedside for using these cells in regenerative medicine, drug discovery and safety testing. In order to produce stem cell derived biopharmaceutics and cells for tissue engineering and transplantation, a cost-effective cell-manufacturing technology is essential. Maintenance of pluripotency and stable performance of cells in downstream applications (e.g., cell differentiation) over time is paramount to large scale cell production. Yet that can be difficult to achieve especially if cells are cultured manually where the operator can introduce significant variability as well as be prohibitively expensive to scale-up. To enable high-throughput, large-scale stem cell production and remove operator influence novel stem cell culture protocols using a bench-top multi-channel liquid handling robot were developed that require minimal technician involvement or experience. With these protocols human induced pluripotent stem cells (iPSCs) were cultured in feeder-free conditions directly from a frozen stock and maintained in 96-well plates. Depending on cell line and desired scale-up rate, the operator can easily determine when to passage based on a series of images showing the optimal colony densities for splitting. Then the necessary reagents are prepared to perform a colony split to new plates without a centrifugation step. After 20 passages (~3 months), two iPSC lines maintained stable karyotypes, expressed stem cell markers, and differentiated into cardiomyocytes with high efficiency. The system can perform subsequent high-throughput screening of new differentiation protocols or genetic manipulation designed for 96-well plates. This technology will reduce the labor and technical burden to produce large numbers of identical stem cells for a myriad of applications.

Irradiation and additive combinations on the pathogen reduction and quality of poultry meat.

PubMed

Ahn, Dong U; Kim, Il Suk; Lee, Eun Joo

2013-02-01

Reduction of foodborne illnesses and deaths by improving the safety of poultry products is one of the priority areas in the United States, and developing and implementing effective food processing technologies can be very effective to accomplish that goal. Irradiation is an effective processing technology for eliminating pathogens in poultry meat. Addition of antimicrobial agents during processing can be another approach to control pathogens in poultry products. However, the adoption of irradiation technology by the meat industry is limited because of quality and health concerns about irradiated meat products. Irradiation produces a characteristic aroma as well as alters meat flavor and color that significantly affect consumer acceptance. The generation of a pink color in cooked poultry and off-odor in poultry by irradiation is a critical issue because consumers associate the presence of a pink color in cooked poultry breast meat as contaminated or undercooked, and off-odor in raw meat and off-flavor in cooked meat with undesirable chemical reactions. As a result, the meat industry has difficulties in using irradiation to achieve its food safety benefits. Antimicrobials such as sodium lactate, sodium diacetate, and potassium benzoate are extensively used to extend the shelf-life and ensure the safety of meat products. However, the use of these antimicrobial agents alone cannot guarantee the safety of poultry products. It is known that some of the herbs, spices, and antimicrobials commonly used in meat processing can have synergistic effects with irradiation in controlling pathogens in meat. Also, the addition of spices or herbs in irradiated meat improves the quality of irradiated poultry by reducing lipid oxidation and production of off-odor volatiles or masking off-flavor. Therefore, combinations of irradiation with these additives can accomplish better pathogen reduction in meat products than using them alone even at lower levels of antimicrobials/herbs and

Anaerobic sludge digestion with a biocatalytic additive

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ghosh, S.; Henry, M.P.; Fedde, P.A.

1982-01-01

The objective of this research was to evaluate the effects of a lactobacillus additive an anaerobic sludge digestion under normal, variable, and overload operating conditions. The additive was a whey fermentation product of an acid-tolerant strain of Lactobacillus acidophilus fortified with CaCO/sub 3/, (NH/sub 4/)/sub 2/HPO/sub 4/, ferrous lactate, and lactic acid. The lactobacillus additive is multifunctional in nature and provides growth factors, metabolic intermediates, and enzymes needed for substrate degradation and cellular synthesis. The experimental work consisted of several pairs of parallel mesophilic (35/sup 0/C) digestion runs (control and test) conducted in five experimental phases. Baseline runs without themore » additive showed that the two experimental digesters had the same methane content, gas production rate (GPR), and ethane yield. The effect of the additive was to increase methane yield and GPR by about 5% (which was statistically significant) during digester operation at a loading rate (LR) of 3.2 kg VS/m/sup 3/-day and a hydraulic retention time (HRT) of 14 days. Data collected from the various experimental phases showed that the biochemical additive increased methane yield, gas production rate, and VS reduction, and decreased volatile acids accumulation. In addition, it enhanced digester buffer capacity and improved the fertilizer value and dewatering characteristics of the digested residue.« less

Effects of particle size of processed barley grain, enzyme addition and microwave treatment on in vitro disappearance and gas production for feedlot cattle.

PubMed

Tagawa, Shin-Ichi; Holtshausen, Lucia; McAllister, Tim A; Yang, Wen Zhu; Beauchemin, Karen Ann

2017-04-01

The effects of particle size of processed barley grain, enzyme addition and microwave treatment on in vitro dry matter (DM) disappearance (DMD), gas production and fermentation pH were investigated for feedlot cattle. Rumen fluid from four fistulated feedlot cattle fed a diet of 860 dry-rolled barley grain, 90 maize silage and 50 supplement g/kg DM was used as inoculum in 3 batch culture in vitro studies. In Experiment 1, dry-rolled barley and barley ground through a 1-, 2-, or 4-mm screen were used to obtain four substrates differing in particle size. In Experiment 2, cellulase enzyme (ENZ) from Acremonium cellulolyticus Y-94 was added to dry-rolled and ground barley (2-mm) at 0, 0.1, 0.5, 1, and 2 mg/g, while Experiment 3 examined the interactions between microwaving (0, 30, and 60 s microwaving) and ENZ addition (0, 1, and 2 mg/g) using dry-rolled barley and 2-mm ground barley. In Experiment 1, decreasing particle size increased DMD and gas production, and decreased fermentation pH (p<0.01). The DMD (g/kg DM) of the dry-rolled barley after 24 h incubation was considerably lower (p<0.05) than that of the ground barley (119.1 dry-rolled barley versus 284.8 for 4-mm, 341.7 for 2-mm; and 358.6 for 1-mm). In Experiment 2, addition of ENZ to dry-rolled barley increased DMD (p<0.01) and tended to increase (p = 0.09) gas production and decreased (p<0.01) fermentation pH, but these variables were not affected by ENZ addition to ground barley. In Experiment 3, there were no interactions between microwaving and ENZ addition after microwaving for any of the variables. Microwaving had minimal effects (except decreased fermentation pH), but consistent with Experiment 2, ENZ addition increased (p<0.01) DMD and gas production, and decreased (p<0.05) fermentation pH of dry-rolled barley, but not ground barley. We conclude that cellulase enzymes can be used to increase the rumen disappearance of barley grain when it is coarsely processed as in the case of dry-rolled barley

Staying Well at Work.

ERIC Educational Resources Information Center

Blai, Boris, Jr.

Employee wellness directly affects business/industry operations and costs. When employees are helped and encouraged to stay well, this people-positive policy results in triple benefits: reduced worker absenteeism, increased employee productivity, and lower company expenditures for health costs. Health care programs at the worksite offer these…

Make or Buy: Cost Impacts of Additive Manufacturing, 3D Laser Scanning Technology, and Collaborative Product Lifecycle Management on Ship Maintenance and Modernization

DTIC Science & Technology

2015-05-01

management during operations 4 Potential Technology 3: Additive Manufacturing (“ 3D Printing ”) 5 • 3D design/image (e.g. from 3D LS) of final part...1 Make or Buy: Cost Impacts of Additive Manufacturing, 3D Laser Scanning Technology, and Collaborative Product Lifecycle Management on Ship...DATES COVERED 00-00-2015 to 00-00-2015 4. TITLE AND SUBTITLE Make or Buy: Cost Impacts of Additive Manufacturing, 3D Laser Scanning Technology

Hydraulics of wells

USGS Publications Warehouse

McLaughlin, Thad G.

1955-01-01

Although the subject of this lecture is supposed to be concerned primarily with the hydraulics of wells, Professor Weers has asked that I also discuss the effects tat geological formations have on the quantity and quality of water available to wells. I will discuss the geology of Colorado in relation to the availability and quality of water with particular reference to the most productive aquifers or water-bearing formations in the State. I will then discuss the hydraulics of wells with the aim of emphasizing the differences between water-table and artesian conditions.

40 CFR 300.920 - Addition of products to Schedule.

Code of Federal Regulations, 2011 CFR

2011-07-01

... manufacturer of his decision in writing. (b) Surface washing agents, surface collecting agents, bioremediation... collecting agent, bioremediation agent, or miscellaneous oil spill control agent to the NCP Product Schedule... collecting agent, bioremediation agent, or miscellaneous oil spill control agent. On the basis of this data...

40 CFR 300.920 - Addition of products to Schedule.

Code of Federal Regulations, 2014 CFR

2014-07-01

... manufacturer of his decision in writing. (b) Surface washing agents, surface collecting agents, bioremediation... collecting agent, bioremediation agent, or miscellaneous oil spill control agent to the NCP Product Schedule... collecting agent, bioremediation agent, or miscellaneous oil spill control agent. On the basis of this data...

40 CFR 300.920 - Addition of products to Schedule.

Code of Federal Regulations, 2012 CFR

2012-07-01

... manufacturer of his decision in writing. (b) Surface washing agents, surface collecting agents, bioremediation... collecting agent, bioremediation agent, or miscellaneous oil spill control agent to the NCP Product Schedule... collecting agent, bioremediation agent, or miscellaneous oil spill control agent. On the basis of this data...

40 CFR 300.920 - Addition of products to Schedule.

Code of Federal Regulations, 2013 CFR

2013-07-01

... manufacturer of his decision in writing. (b) Surface washing agents, surface collecting agents, bioremediation... collecting agent, bioremediation agent, or miscellaneous oil spill control agent to the NCP Product Schedule... collecting agent, bioremediation agent, or miscellaneous oil spill control agent. On the basis of this data...

40 CFR 300.920 - Addition of products to Schedule.

Code of Federal Regulations, 2010 CFR

2010-07-01

... manufacturer of his decision in writing. (b) Surface washing agents, surface collecting agents, bioremediation... collecting agent, bioremediation agent, or miscellaneous oil spill control agent to the NCP Product Schedule... collecting agent, bioremediation agent, or miscellaneous oil spill control agent. On the basis of this data...

76 FR 57719 - Procurement List; Proposed Additions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-16

... the Federal Government identified in this notice will be required to procure the products and services... to furnish the products and services to the Government. 3. There are no known regulatory alternatives... with the products and services proposed for addition to the Procurement List. Comments on this...

Additive direct-write microfabrication for MEMS: A review

NASA Astrophysics Data System (ADS)

Teh, Kwok Siong

2017-12-01

Direct-write additive manufacturing refers to a rich and growing repertoire of well-established fabrication techniques that builds solid objects directly from computer- generated solid models without elaborate intermediate fabrication steps. At the macroscale, direct-write techniques such as stereolithography, selective laser sintering, fused deposition modeling ink-jet printing, and laminated object manufacturing have significantly reduced concept-to-product lead time, enabled complex geometries, and importantly, has led to the renaissance in fabrication known as the maker movement. The technological premises of all direct-write additive manufacturing are identical—converting computer generated three-dimensional models into layers of two-dimensional planes or slices, which are then reconstructed sequentially into threedimensional solid objects in a layer-by-layer format. The key differences between the various additive manufacturing techniques are the means of creating the finished layers and the ancillary processes that accompany them. While still at its infancy, direct-write additive manufacturing techniques at the microscale have the potential to significantly lower the barrier-of-entry—in terms of cost, time and training—for the prototyping and fabrication of MEMS parts that have larger dimensions, high aspect ratios, and complex shapes. In recent years, significant advancements in materials chemistry, laser technology, heat and fluid modeling, and control systems have enabled additive manufacturing to achieve higher resolutions at the micrometer and nanometer length scales to be a viable technology for MEMS fabrication. Compared to traditional MEMS processes that rely heavily on expensive equipment and time-consuming steps, direct-write additive manufacturing techniques allow for rapid design-to-prototype realization by limiting or circumventing the need for cleanrooms, photolithography and extensive training. With current direct-write additive

16 CFR § 1102.16 - Additional information.

Code of Federal Regulations, 2013 CFR

2013-01-01

... PUBLICLY AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE Content Requirements § 1102.16 Additional... in the Database any additional information it determines to be in the public interest, consistent...

Triticale crisp bread enriched with selected bioactive additives: volatile profile, physical characteristics, sensory and nutritional properties.

PubMed

Makowska, Agnieszka; Majcher, Małgorzata; Mildner-Szkudlarz, Sylwia; Jedrusek-Golinska, Anna; Przygoński, Krzysztof

2017-09-01

The effect of selected plant additives (couch grass, artichoke, kale, nettle, ground buckwheat husks, broad beans, fenugreek seeds, and extracts of yellow tea and mulberry leaf) on the volatile compounds, color, texture, sensory attributes, polyphenols, and antioxidant properties of triticale crisp bread was studied. The volatile profile of control bread was dominated by lipid oxidation products with hexanal and (E)-2-nonenal predominant. The additives strongly modified the volatile profile of the extruded crisp bread. The greatest differences were recorded in the case of products with artichoke and kale additions, which had respectively about 12 and 8 times higher levels of total volatile compounds than the control crisp bread. The samples containing kale, buckwheat, and fenugreek as well as yellow tea extract characterized high levels of sulfur compounds, with methanethiol predominant. The additives, especially kale, nettle, and artichoke affected the color of the crisp breads, in most cases making them darker. In terms of texture only the crisp bread with addition of buckwheat husk was significantly harder than the control sample. On the basis of sensory evaluation it was stated that among all the additives, the artichoke and fenugreek resulted in dramatic deterioration in the extruded product taste. The used additives also affected the antioxidant properties of triticale crisp bread. The greatest content of total phenolic compounds and the highest antioxidant activity were observed for the bread with yellow tea extract addition (3.5- and 6.5-fold higher, respectively, than in control sample).

Advances in High Temperature Materials for Additive Manufacturing

NASA Astrophysics Data System (ADS)

Nordin, Nurul Amira Binti; Johar, Muhammad Akmal Bin; Ibrahim, Mohd Halim Irwan Bin; Marwah, Omar Mohd Faizan bin

2017-08-01

In today’s technology, additive manufacturing has evolved over the year that commonly known as 3D printing. Currently, additive manufacturing have been applied for many industries such as for automotive, aerospace, medical and other commercial product. The technologies are supported by materials for the manufacturing process to produce high quality product. Plus, additive manufacturing technologies has been growth from the lowest to moderate and high technology to fulfil manufacturing industries obligation. Initially from simple 3D printing such as fused deposition modelling (FDM), poly-jet, inkjet printing, to selective laser sintering (SLS), and electron beam melting (EBM). However, the high technology of additive manufacturing nowadays really needs high investment to carry out the process for fine products. There are three foremost type of material which is polymer, metal and ceramic used for additive manufacturing application, and mostly they were in the form of wire feedstock or powder. In circumstance, it is crucial to recognize the characteristics of each type of materials used in order to understand the behaviours of the materials on high temperature application via additive manufacturing. Therefore, this review aims to provide excessive inquiry and gather the necessary information for further research on additive material materials for high temperature application. This paper also proposed a new material based on powder glass, which comes from recycled tempered glass from automotive industry, having a huge potential to be applied for high temperature application. The technique proposed for additive manufacturing will minimize some cost of modelling with same quality of products compare to the others advanced technology used for high temperature application.

Additive erosion reduction influences in the turbulent boundary layer

NASA Astrophysics Data System (ADS)

Buckingham, A. C.

1981-05-01

Results of a sequence of flow, heat and mass transfer calculations are presented which theoretically characterize the erosive environment at the wall surface of refractory metal coated and uncoated gun barrels. The theoretical results include analysis of the wall surface temperature, heat flux, and shear stress time histories on thin (10 mil.) Cr, Mo, Nb, and Ta plated steel barrel walls as uncoated steel walls. The calculations combine effects of a number of separate processes which were previously (and purposely) studied individually. These include solid particle additive concentrations, gas wall thermochemical influences, and transient turbulent wall boundary layer flow with multicomponent molecular diffusion and reactions from interaction of propellant combustion and the eroding surface. The boundary layer model includes particulate additive concentrations as well as propellant combustion products, considered for the present to be in the local thermochemical equilibrium.

27 CFR 19.967 - Additional security.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Additional security. 19.967 Section 19.967 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Distilled Spirits For Fuel Use Construction...

75 FR 36362 - Procurement List Additions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-25

... additions to the Procurement List. Glove, Mechanic's A commercial company submitted comments objecting to... provide the mechanic's gloves in compliance with the Acts cited by CamelBak in its correspondence to the... Accordingly, the following products and services are added to the Procurement List: Products Glove, Mechanic's...

Geothermally Coupled Well-Based Compressed Air Energy Storage

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davidson, Casie L.; Bearden, Mark D.; Horner, Jacob A.

2015-12-20

Previous work by McGrail et al. (2013, 2015) has evaluated the possibility of pairing compressed air energy storage with geothermal resources in lieu of a fossil-fired power generation component, and suggests that such applications may be cost competitive where geology is favorable to siting both the geothermal and CAES components of such a system. Those studies also note that the collocation of subsurface resources that meet both sets of requirements are difficult to find in areas that also offer infrastructure and near- to mid-term market demand for energy storage. This study examines a novel application for the compressed air storagemore » portion of the project by evaluating the potential to store compressed air in disused wells by amending well casings to serve as subsurface pressure vessels. Because the wells themselves would function in lieu of a geologic storage reservoir for the CAES element of the project, siting could focus on locations with suitable geothermal resources, as long as there was also existing wellfield infrastructure that could be repurposed for air storage. Existing wellfields abound in the United States, and with current low energy prices, many recently productive fields are now shut in. Should energy prices remain stagnant, these idle fields will be prime candidates for decommissioning unless they can be transitioned to other uses, such as redevelopment for energy storage. In addition to the nation’s ubiquitous oil and gas fields, geothermal fields, because of their phased production lifetimes, also may offer many abandoned wellbores that could be used for other purposes, often near currently productive geothermal resources. These existing fields offer an opportunity to decrease exploration and development uncertainty by leveraging data developed during prior field characterization, drilling, and production. They may also offer lower-cost deployment options for hybrid geothermal systems via redevelopment of existing well

Penrose Well Temperatures

DOE Data Explorer

Christopherson, Karen

2013-03-15

Penrose Well Temperatures Geothermal waters have been encountered in several wells near Penrose in Fremont County, Colorado. Most of the wells were drilled for oil and gas exploration and, in a few cases, production. This ESRI point shapefile utilizes data from 95 wells in and around the Penrose area provided by the Colorado Oil and Gas Conservation Commission (COGCC) database at http://cogcc.state.co.us/ . Temperature data from the database were used to calculate a temperature gradient for each well. This information was then used to estimate temperatures at various depths. Projection: UTM Zone 13 NAD27 Extent: West -105.224871 East -105.027633 North 38.486269 South 38.259507 Originators: Colorado Oil and Gas Conservation Commission (COGCC) Karen Christopherson

Elaboration And Characterization Of Foam Glass Based On Cullet With Addition Of Soluble Silicates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ayadi, A.; Stiti, N.; Benhaoua, F.

2011-01-17

The politics of the energy saving and of the acoustic comfort buildings is at the heart of the research of new compounds permitting to improve the materials performance actually commercialised. With this aim in view, we'll purpose to elaborate a porous material (foam glass) with addition of soluble silicates (up to 40%) of which the principal material is the waste glass in order to recycle it and improving the present laws about the waste products in closed circuit: (Finished products (leftarrow) waste products (leftarrow) finished products). The investigations have shown that grinding waste glass to particle size less than 0.1more » mm and adding 1% of Ca CO{sub 3} content provide production of material with the following properties: particle density 0,5 g/cm{sup 3}, strength 17,50 MPa and water adsorption 95%, the temperature for foaming ranges were determined at 850 deg. C. The microstructures are homogenous, with pore sizes up to 2 mm. The addition of soluble silicates (up to 40%) has resulted in the foam glass of very high porosity. The foam glass is counted among the new glass products meeting certain requirements sought comfort in the building industry in particular (thermal and acoustic insulation). The product obtained present of excellent properties thermal ({lambda} = 0,031 W/m deg. C) and acoustic (R = 15 dB).« less

Folate content in fresh-cut vegetable packed products by 96-well microtiter plate microbiological assay.

PubMed

Fajardo, Violeta; Alonso-Aperte, Elena; Varela-Moreiras, Gregorio

2015-02-15

Ready-to-eat foods have nowadays become a significant portion of the diet. Accordingly, nutritional composition of these food categories should be well-known, in particular its folate content. However, there is a broad lack of folate data in food composition tables and databases. A total of 21 fresh-cut vegetable and fruit packed products were analysed for total folate (TF) content using a validated method that relies on the folate-dependent growth of chloramphenicol-resistant Lactobacillus casei subspecies rhamnosus (NCIMB 10463). Mean TF content ranged from 10.0 to 140.9μg/100g for the different matrices on a fresh weight basis. Higher TF quantity, 140.9-70.1μg/100g, was found in spinach, rocket, watercress, chard and broccoli. Significant differences were observed between available data for fresh vegetables and fruits from food composition tables or databases and the analysed results for fresh-cut packed products. Supplied data support the potential of folate-rich fresh-cut ready-to-eat vegetables to increase folate intake significantly. Copyright © 2014 Elsevier Ltd. All rights reserved.

Optimization of Geothermal Well Placement under Geological Uncertainty

NASA Astrophysics Data System (ADS)

Schulte, Daniel O.; Arnold, Dan; Demyanov, Vasily; Sass, Ingo; Geiger, Sebastian

2017-04-01

Well placement optimization is critical to commercial success of geothermal projects. However, uncertainties of geological parameters prohibit optimization based on a single scenario of the subsurface, particularly when few expensive wells are to be drilled. The optimization of borehole locations is usually based on numerical reservoir models to predict reservoir performance and entails the choice of objectives to optimize (total enthalpy, minimum enthalpy rate, production temperature) and the development options to adjust (well location, pump rate, difference in production and injection temperature). Optimization traditionally requires trying different development options on a single geological realization yet there are many possible different interpretations possible. Therefore, we aim to optimize across a range of representative geological models to account for geological uncertainty in geothermal optimization. We present an approach that uses a response surface methodology based on a large number of geological realizations selected by experimental design to optimize the placement of geothermal wells in a realistic field example. A large number of geological scenarios and design options were simulated and the response surfaces were constructed using polynomial proxy models, which consider both geological uncertainties and design parameters. The polynomial proxies were validated against additional simulation runs and shown to provide an adequate representation of the model response for the cases tested. The resulting proxy models allow for the identification of the optimal borehole locations given the mean response of the geological scenarios from the proxy (i.e. maximizing or minimizing the mean response). The approach is demonstrated on the realistic Watt field example by optimizing the borehole locations to maximize the mean heat extraction from the reservoir under geological uncertainty. The training simulations are based on a comprehensive semi

Groundwater data for selected wells within the Eastern San Joaquin Groundwater Subbasin, California, 2003-8

USGS Publications Warehouse

Clark, Dennis A.; Izbicki, John A.; Metzger, Loren F.; Everett, Rhett; Smith, Gregory A.; O'Leary, David R.; Teague, Nicholas F.; Burgess, Matthew K.

2012-01-01

Data were collected by the U.S. Geological Survey from 2003 through 2008 in the Eastern San Joaquin Groundwater Subbasin, 80 miles east of San Francisco, California, as part of a study of the increasing chloride concentrations in groundwater processes. Data collected include geologic, geophysical, chemical, and hydrologic data collected during and after the installation of five multiple-well monitoring sites, from three existing multiple-well sites, and from 79 selected public-supply, irrigation, and domestic wells. Each multiple-well monitoring site installed as part of this study contained three to five 2-inch diameter polyvinyl chloride (PVC)-cased wells ranging in depth from 68 to 880 feet below land surface. Continuous water-level data were collected from the 19 wells installed at these 5 sites and from 10 existing monitoring wells at 3 additional multiple-well sites in the study area. Thirty-one electromagnetic logs were collected seasonally from the deepest PVC-cased monitoring well at seven multiple-well sites. About 200 water samples were collected from 79 wells in the study area. Coupled well-bore flow data and depth-dependent water-quality data were collected from 12 production wells under pumped conditions, and well-bore flow data were collected from 10 additional wells under unpumped conditions.

Additives in plastics.

PubMed Central

Deanin, R D

1975-01-01

The polymers used in plastics are generally harmless. However, they are rarely used in pure form. In almost all commercial plastics, they are "compounded" with monomeric ingredients to improve their processing and end-use performance. In order of total volume used, these monomeric additives may be classified as follows: reinforcing fibers, fillers, and coupling agents; plasticizers; colorants; stabilizers (halogen stabilizers, antioxidants, ultraviolet absorbers, and biological preservatives); processing aids (lubricants, others, and flow controls); flame retardants, peroxides; and antistats. Some information is already available, and much more is needed, on potential toxicity and safe handling of these additives during processing and manufacture of plastics products. PMID:1175566

49 CFR 1300.5 - Additional publication requirement for agricultural products and fertilizer.

Code of Federal Regulations, 2013 CFR

2013-10-01

... agricultural products and fertilizer. 1300.5 Section 1300.5 Transportation Other Regulations Relating to... fertilizer. (a) With respect to transportation of agricultural products (including grain, as defined in 7 U.S.C. 75, and all products thereof) and fertilizer, a rail carrier shall publish, make available, and...

49 CFR 1300.5 - Additional publication requirement for agricultural products and fertilizer.

Code of Federal Regulations, 2014 CFR

2014-10-01

... agricultural products and fertilizer. 1300.5 Section 1300.5 Transportation Other Regulations Relating to... fertilizer. (a) With respect to transportation of agricultural products (including grain, as defined in 7 U.S.C. 75, and all products thereof) and fertilizer, a rail carrier shall publish, make available, and...

49 CFR 1300.5 - Additional publication requirement for agricultural products and fertilizer.

Code of Federal Regulations, 2012 CFR

2012-10-01

... agricultural products and fertilizer. 1300.5 Section 1300.5 Transportation Other Regulations Relating to... fertilizer. (a) With respect to transportation of agricultural products (including grain, as defined in 7 U.S.C. 75, and all products thereof) and fertilizer, a rail carrier shall publish, make available, and...

49 CFR 1300.5 - Additional publication requirement for agricultural products and fertilizer.

Code of Federal Regulations, 2010 CFR

2010-10-01

... agricultural products and fertilizer. 1300.5 Section 1300.5 Transportation Other Regulations Relating to... fertilizer. (a) With respect to transportation of agricultural products (including grain, as defined in 7 U.S.C. 75, and all products thereof) and fertilizer, a rail carrier shall publish, make available, and...

49 CFR 1300.5 - Additional publication requirement for agricultural products and fertilizer.

Code of Federal Regulations, 2011 CFR

2011-10-01

... agricultural products and fertilizer. 1300.5 Section 1300.5 Transportation Other Regulations Relating to... fertilizer. (a) With respect to transportation of agricultural products (including grain, as defined in 7 U.S.C. 75, and all products thereof) and fertilizer, a rail carrier shall publish, make available, and...

Induction of antroquinonol production by addition of hydrogen peroxide in the fermentation of Antrodia camphorata S-29.

PubMed

Xia, Yongjun; Zhou, Xuan; Wang, Guangqiang; Zhang, Bobo; Xu, Ganrong; Ai, Lianzhong

2017-01-01

Antroquinonol have significantly anti-tumour effects on various cancer cells. There is still lack of reports on regulation of environmental factors on antroquinonol production by Antrodia camphorata. An effective submerged fermentation method was employed to induce antroquinonol with adding H 2 O 2 . The production of antroquinonol was 57.81 mg L -1 after fermentation for 10 days when adding 25 mmol L -1 H 2 O 2 at day 4 of the fermentation process. Then, antroquinonol was further increased to 80.10 mg L -1 with cell productivity of 14.94 mg g -1 dry mycelium when the feeding rate of H 2 O 2 was adjusted to 0.2 mmol L -1 h -1 in the 7 L fermentation bioreactor. After inhibiting the generation of reactive oxygen species with the inhibitor diphenyleneiodoium, the synthesis of antroquinonol from A. camphorata was significantly reduced, and the yield was only 3.3 mg L -1 . The results demonstrated that addition of H 2 O 2 was a very effective strategy to induce and regulate the synthesis of antroquinonol in submerged fermentation. Reactive oxygen species generated by H 2 O 2 during fermentation caused oxidative stress, which induced the synthesis of antroquinonol and other chemical compounds. Moreover, it is very beneficial process to improve production and diversity of the active compounds during liquid fermentation of A. camphorata mycelium. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

Bacterial communities associated with production facilities of two newly drilled thermogenic natural gas wells in the Barnett Shale (Texas, USA).

PubMed

Davis, James P; Struchtemeyer, Christopher G; Elshahed, Mostafa S

2012-11-01

We monitored the bacterial communities in the gas-water separator and water storage tank of two newly drilled natural gas wells in the Barnett Shale in north central Texas, using a 16S rRNA gene pyrosequencing approach over a period of 6 months. Overall, the communities were composed mainly of moderately halophilic and halotolerant members of the phyla Firmicutes and Proteobacteria (classes Βeta-, Gamma-, and Epsilonproteobacteria) in both wells at all sampling times and locations. Many of the observed lineages were encountered in prior investigations of microbial communities from various fossil fluid formations and production facilities. In all of the samples, multiple H(2)S-producing lineages were encountered; belonging to the sulfate- and sulfur-reducing class Deltaproteobacteria, order Clostridiales, and phylum Synergistetes, as well as the thiosulfate-reducing order Halanaerobiales. The bacterial communities from the separator and tank samples bore little resemblance to the bacterial communities in the drilling mud and hydraulic-fracture waters that were used to drill these wells, suggesting the in situ development of the unique bacterial communities in such well components was in response to the prevalent geochemical conditions present. Conversely, comparison of the bacterial communities on temporal and spatial scales suggested the establishment of a core microbial community in each sampled location. The results provide the first overview of bacterial dynamics and colonization patterns in newly drilled, thermogenic natural gas wells and highlights patterns of spatial and temporal variability observed in bacterial communities in natural gas production facilities.

Improvement of organoleptic quality of retted cassava products by alkali pretreatment of roots and addition of sodium nitrate during retting.

PubMed

Ogbo, Frank C

2003-12-15

Alkali pretreatment of cassava roots before retting and addition of sodium nitrate during retting were used to manipulate the metabolism of microorganisms involved in cassava (Manihot esculenta Crantz) retting, as a method for removing the characteristic offensive odour of retted cassava products. Odour was assessed by organoleptic methods. The characteristics of fermentation of cassava by the traditional method (control) were as follows; aerobic mesophilic count (APC) on nutrient agar (NA) at 30 degrees C/48 h, attained a maximum of 2.3 x 10(7)/ml retting juice while counts on de Man Rogosa and Sharpe agar (MRS) at 30 degrees C/48 h were 1.6 x 10(8)/ml. Maximum titrable acidity was 0.062% lactic acid by weight of retting juice. Cassava was retted in 3 days and the product exhibited characteristic offensive odour. Addition of NaNO3 into retting water effectively removed odour at a concentration of 0.3 g/l. Maximum APC on NA/30 degrees C/48 h was 6.8 x 10(6)/ml. Counts on MRS/30 degrees C/48 h exceeded 2.4 x 10(9)/ml. Retting was complete in 3 days with a final titrable acidity of 0.068% of retting juice. Removal of odour likely resulted from selection of homo-fermentative lactic acid bacteria, thus producing mostly odourless lactic acid. Alkali pretreatment of roots before retting was efficacious in removing odour at a concentration of 10 g/l for 30 min. This fermentation was characterized by APC on NA/30 degrees C/48 h of 5.4 x 10(6)/ml; MRS/30 degrees C/48 h reached a maximum of only 10 x 10(4)/ml and correspondingly low titrable acidity of 0.003%. Low counts of lactic acid bacteria correlate well with the absence of odour in this sample. Both treatments did not adversely affect the detoxification process, yielding "foo-foo" with HCN levels lower than 10 mg/kg. Residual nitrates and nitrites of 30 mg/kg in the sodium nitrate-treated sample were also within the safe limits of 156 mg/kg allowed in many countries. Organoleptically improved samples were acceptable to

Health, wellness and the allure of spices in the Middle Ages.

PubMed

Freedman, Paul

2015-06-05

During the European Middle Ages aromatic products imported from Asia and Africa were credited with both preventive and curative medical properties. In addition spices provided an image of wellness and as they were expensive and had many uses in cuisine and fragrance, they functioned as prestige consumer goods. This is an effort to look historically at a social and cultural phenomenon for the period roughly A.D. 1200-1500. Sources of information about the demand for and uses of spices include lists of materia medica, medical treatises, cookbooks, religious writings, descriptions of banquets and court ceremonial and literary works showing what might be called aspirational lifestyles. It is important to focus on the demand side of the spice trade rather than simply assuming a consistent demand and looking only at the supply (prices, routes, for example). The demand for spices must be understood in terms of their attributed medical and wellness powers, but these in turn are related to the mysterious Eastern origins of spices that enhanced their image as elite consumer products and their association with spiritual as well as medical healing. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scott Reeves

2003-03-01

Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Continued to solicit industry research partners to provide test sites. A Cooperative Research Agreement has been signed with Oneok, for a test site in the Mocane-Laverne field in the Anadarko basin (Oklahoma). The site

27 CFR 19.343 - Addition of oak chips to spirits and addition of caramel to brandy and rum.

Code of Federal Regulations, 2010 CFR

2010-04-01

... spirits and addition of caramel to brandy and rum. 19.343 Section 19.343 Alcohol, Tobacco Products and... PLANTS Storage § 19.343 Addition of oak chips to spirits and addition of caramel to brandy and rum. Oak... records. Caramel possessing no material sweetening properties may be added to rum or brandy in packages or...

Enhancing phosphorus release from waste activated sludge containing ferric or aluminum phosphates by EDTA addition during anaerobic fermentation process.

PubMed

Zou, Jinte; Zhang, Lili; Wang, Lin; Li, Yongmei

2017-03-01

The effect of ethylene diamine tetraacetic acid (EDTA) addition on phosphorus release from biosolids and phosphate precipitates during anaerobic fermentation was investigated. Meanwhile, the impact of EDTA addition on the anaerobic fermentation process was revealed. The results indicate that EDTA addition significantly enhanced the release of phosphorus from biosolids, ferric phosphate precipitate and aluminum phosphate precipitate during anaerobic fermentation, which is attributed to the complexation of metal ions and damage of cell membrane caused by EDTA. With the optimal EDTA addition of 19.5 mM (0.41 gEDTA/gSS), phosphorus release efficiency from biosolids was 82%, which was much higher than that (40%) without EDTA addition. Meanwhile, with 19.5 mM EDTA addition, almost all the phosphorus in ferric phosphate precipitate was released, while only 57% of phosphorus in aluminum phosphate precipitate was released. This indicates that phosphorus in ferric phosphate precipitate was much easier to be released than that in aluminum phosphate precipitate during anaerobic fermentation of sludge. In addition, proper EDTA addition facilitated the production of soluble total organic carbon and volatile fatty acids, as well as solid reduction during sludge fermentation, although methane production could be inhibited. Therefore, EDTA addition can be used as an alternative method for recovering phosphorus from waste activated sludge containing ferric or aluminum precipitates, as well as recovery of soluble carbon source. Copyright © 2016 Elsevier Ltd. All rights reserved.

Potassium ferrate addition as an alternative pre-treatment to enhance short-chain fatty acids production from waste activated sludge.

PubMed

He, Zhang-Wei; Liu, Wen-Zong; Gao, Qin; Tang, Cong-Cong; Wang, Ling; Guo, Ze-Chong; Zhou, Ai-Juan; Wang, Ai-Jie

2018-01-01

A potentially practical technology based on ferrate (VI), i.e. potassium ferrate (PF), pretreatment integrated into waste activated sludge (WAS) anaerobic fermentation has been presented to greatly enhance short-chain fatty acids (SCFAs) production with a shortened fermentation time. The maximum production of SCFAs, 343mg chemical oxygen demand/g volatile suspended solid with acetic acid proportion of 48.2%, was obtained with PF dosage of 56mg Fe(VI)/g total suspended solid within 5days, which was increased to 5.72times compared to that of control. The mechanism study showed that PF accelerated the release rate of both intracellular and extracellular constituents. And the activities of key hydrolytic enzymes were much improved with PF addition. Moreover, PF positively enriched the abundance of microorganisms responsible for WAS hydrolysis and SCFAs production, especially acetic acid-forming characteristic genera such as Petrimonas, Fusibacter and Acetoanaerobium. Besides, the incubation time of acidogenesis and methanogenesis were separated by PF. Copyright © 2017 Elsevier Ltd. All rights reserved.

77 FR 33269 - Designation of Product Categories for Federal Procurement

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-05

... under such a contract.'' Thus, Federal contractors, as well as Federal agencies, are expressly subject... generally to procure such a product composed of the highest percentage of recovered materials content... those product categories that contain the highest biobased content. In addition, as the program matures...

A novel direct screening method for alkyl glucoside production by glucosidases expressed in E. coli in 96-well plates.

PubMed

Gräber, Martin; Andersson, Mats; Rundbäck, Fabian; Pozzo, Tania; Karlsson, Eva Nordberg; Adlercreutz, Patrick

2010-01-15

The present work describes the development of a novel direct screening method, assayed in 96-well format, for evaluation of enzymatic alkyl glycoside production in a hexanol-water two-phase system. Alkyl glycosides are surfactants with a range of applications and with good biodegradability and low toxicity. Enzymatic synthesis makes it possible to prepare beta-d-glucopyranosides with high purity. In the developed screening assay, hexyl-beta-d-glucopyranoside was chosen as a model product to be synthesised by reversed hydrolysis in a water-hexanol two-phase system. In a first step the model product is produced by glucosidases expressed in E. coli cells in 96-deep-well plates. After phase separation, the hexyl-beta-d-glucopyranoside in the organic phase is degraded enzymatically and the released glucose detected spectrophotometrically at 405nm utilizing peroxidase/glucose oxidase, and the reagent 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS). The aqueous phase is used to monitor hydrolysis of p-NPG at 405nm, allowing use of a ratio of the two assays to compensate for expression differences. The complete method was used for comparison of two different beta-glucosidases, classified under glycoside hydrolase family 1 and 3, respectively, showing a significant difference in their ability to synthesise hexyl-beta-d-glucopyranoside by reversed hydrolysis.

78 FR 40727 - Procurement List; Proposed Additions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-08

... for addition to the Procurement List for production by the nonprofit agencies listed: Products Towel.... 12/BX Cleaner, Brake Parts NSN: 6850-01-167-0678--17 oz. NPA: The Lighthouse for the Blind, St. Louis...

77 FR 15736 - Procurement List; Proposed Additions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-16

... additions to the Procurement List. SUMMARY: The Committee is proposing to add a product and services to the... identified in this notice will be required to procure the product and services listed below from nonprofit... entities other than the small organizations that will furnish the product and services to the Government. 2...

78 FR 17835 - Approval and Promulgation of Federal Implementation Plan for Oil and Natural Gas Well Production...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-22

...The EPA is taking final action to promulgate a Reservation- specific Federal Implementation Plan in order to regulate emissions from oil and natural gas production facilities located on the Fort Berthold Indian Reservation in North Dakota. The Federal Implementation Plan includes basic air quality regulations for the protection of communities in and adjacent to the Fort Berthold Indian Reservation. The Federal Implementation Plan requires owners and operators of oil and natural gas production facilities to reduce emissions of volatile organic compounds emanating from well completions, recompletions, and production and storage operations. This Federal Implementation Plan will be implemented by the EPA, or a delegated tribal authority, until replaced by a Tribal Implementation Plan. The EPA proposed a Reservation-specific Federal Implementation Plan concurrently with an interim final rule on August 15, 2012. This final Federal Implementation Plan replaces the interim final rule in all intents and purposes on the effective date of the final rule. The EPA is taking this action pursuant to the Clean Air Act (CAA).

Reduction of nitrate in aquifer microcosms by carbon additions

USGS Publications Warehouse

Obenhuber, Donald C.; Lowrance , Richard

1991-01-01

Aquifer microcosms were used to examine the effects of NO−3 and C amendments on groundwater from the Claiborne aquifer. Nitrate concentrations of 12.17 mg L−1 in aquifer microcosms were reduced 0.92%/d to 5.84 mg L−1 by the addition of 10 mg C L−1 for 35 d. Nitrate disappearance correlated with increases in number of denitrifiers and dissolved N2O concentration and decreases in dissolved oxygen, suggesting biological denitrification. Nitrate/chloride ratios decreased in microcosms with 10 mg C L−1 added and then increased when the C addition was removed. Carbon additions of 0.4 mg C L−1 had no effect on the microbial or chemical properties of the microcosms. Nitrous oxide levels in wells sampling the Claiborne aquifer showed an increase with depth, indicating N2O production within the aquifer. Microcosms are useful tools to examine biological transformations of chemical contaminants in unconsolidated aquifer material. The remediation of NO−3 contaminated aquifers by organic infusion is possible and appears to be a function of microbial denitrification.

A Workplace Mindfulness Intervention May Be Associated With Improved Psychological Well-Being and Productivity. A Preliminary Field Study in a Company Setting.

PubMed

Kersemaekers, Wendy; Rupprecht, Silke; Wittmann, Marc; Tamdjidi, Chris; Falke, Pia; Donders, Rogier; Speckens, Anne; Kohls, Niko

2018-01-01

Background: Mindfulness trainings are increasingly offered in workplace environments in order to improve health and productivity. Whilst promising, there is limited research on the effectiveness of mindfulness interventions in workplace settings. Objective: To examine the feasibility and effectiveness of a Workplace Mindfulness Training (WMT) in terms of burnout, psychological well-being, organizational and team climate, and performance. Methods: This is a preliminary field study in four companies. Self-report questionnaires were administered up to a month before, at start of, and right at the end of the WMT, resulting in a pre-intervention and an intervention period. There was no separate control group. A total of 425 participants completed the surveys on the different time points. Linear mixed model analyses were used to analyze the data. Results: When comparing the intervention period with the pre-intervention period, significantly greater improvements were found in measures of burnout (mean difference = 0.3, p < 0.001), perceived stress (mean difference = -0.2, p < 0.001), mindfulness [mean difference = 1.0 for the Freiburg Mindfulness Inventory (FMI) and 0.8 for the Mindfulness Attention Awareness Scale (MAAS), both p < 0.001], and well-being (mean difference = 0.4, p < 0.001). Additionally, greater increases in team climate, organizational climate and personal performance were reported during the intervention compared to the pre-intervention period with largest improvements in team cooperation (mean difference = 0.3, p < 0.001), productivity (mean difference = 0.5, p < 0.001), and stress (mean difference = -0.4, p < 0.001). Effect sizes were large for mindfulness ( d > 0.8), moderate for well-being, burnout and perceived stress ( d = 0.5-0.8), and ranged from low to moderate for organizational and team climate and personal performance ( d = 0.2-0.8). Conclusion: These preliminary data suggest that compared to the pre-intervention period, the intervention

A Workplace Mindfulness Intervention May Be Associated With Improved Psychological Well-Being and Productivity. A Preliminary Field Study in a Company Setting

PubMed Central

Kersemaekers, Wendy; Rupprecht, Silke; Wittmann, Marc; Tamdjidi, Chris; Falke, Pia; Donders, Rogier; Speckens, Anne; Kohls, Niko

2018-01-01

Background: Mindfulness trainings are increasingly offered in workplace environments in order to improve health and productivity. Whilst promising, there is limited research on the effectiveness of mindfulness interventions in workplace settings. Objective: To examine the feasibility and effectiveness of a Workplace Mindfulness Training (WMT) in terms of burnout, psychological well-being, organizational and team climate, and performance. Methods: This is a preliminary field study in four companies. Self-report questionnaires were administered up to a month before, at start of, and right at the end of the WMT, resulting in a pre-intervention and an intervention period. There was no separate control group. A total of 425 participants completed the surveys on the different time points. Linear mixed model analyses were used to analyze the data. Results: When comparing the intervention period with the pre-intervention period, significantly greater improvements were found in measures of burnout (mean difference = 0.3, p < 0.001), perceived stress (mean difference = -0.2, p < 0.001), mindfulness [mean difference = 1.0 for the Freiburg Mindfulness Inventory (FMI) and 0.8 for the Mindfulness Attention Awareness Scale (MAAS), both p < 0.001], and well-being (mean difference = 0.4, p < 0.001). Additionally, greater increases in team climate, organizational climate and personal performance were reported during the intervention compared to the pre-intervention period with largest improvements in team cooperation (mean difference = 0.3, p < 0.001), productivity (mean difference = 0.5, p < 0.001), and stress (mean difference = -0.4, p < 0.001). Effect sizes were large for mindfulness (d > 0.8), moderate for well-being, burnout and perceived stress (d = 0.5–0.8), and ranged from low to moderate for organizational and team climate and personal performance (d = 0.2–0.8). Conclusion: These preliminary data suggest that compared to the pre-intervention period, the intervention

Effect of glucose and cellulase addition on wet-storage of excessively wilted maize stover and biogas production.

PubMed

Guo, Jianbin; Cui, Xian; Sun, Hui; Zhao, Qian; Wen, Xiaoyu; Pang, Changle; Dong, Renjie

2018-07-01

In north China, large amounts of excessively wilted maize stover are produced annually. Maize stover wet storage strategies and subsequent biogas production was examined in this study. Firstly, wet storage performances of harvested maize stover, air-dried for different time durations, were evaluated. Results showed that optimal storage performance was obtained when the initial water soluble carbohydrate (WSC) content after air-drying was higher than 8.0%. Therefore, cellulase and glucose were added to the excessively wilted maize stover to achieve the targeted pre-storage WSC levels. Good storage performances were observed in treatments with addition of 76.4 g/kg DM glucose and 12.5 g/kg DM of cellulase; the specific methane yield increased by 23.7% and 19.2%, respectively. However, use of glucose as additive or co-storing with high WSC substrates can serve as economically feasible options to adapt wet storage of excessively wilted maize stover. Copyright © 2018 Elsevier Ltd. All rights reserved.

Well-being at work--overview and perspective.

PubMed

Schulte, Paul; Vainio, Harri

2010-09-01

This paper provides an overview of and perspective on the concept of well-being at work. Well-being is a term that reflects not only on one's health but satisfaction with work and life. Well-being is a summative concept that characterizes the quality of working lives, including occupational safety and health (OSH) aspects, and it may be a major determinant of productivity at the individual, enterprise and societal levels. Based on a review of the literature and a recent conference, we suggest a model linking workforce well-being, productivity, and population well-being. To appraise the validity of the model, we consider five questions: (i) is there a robust and usable definition of workplace well-being? (ii) have the variables that influence well-being been aptly described and can they be measured and used in risk assessments? (iii) what is the nature of evidence that well-being is linked to productivity? (iv) what is the state of knowledge on the effectiveness of interventions to promote workplace well-being? and (v) should interventions aimed at improving well-being at work focus on more than work-related factors?

Polylactides in additive biomanufacturing.

PubMed

Poh, Patrina S P; Chhaya, Mohit P; Wunner, Felix M; De-Juan-Pardo, Elena M; Schilling, Arndt F; Schantz, Jan-Thorsten; van Griensven, Martijn; Hutmacher, Dietmar W

2016-12-15

New advanced manufacturing technologies under the alias of additive biomanufacturing allow the design and fabrication of a range of products from pre-operative models, cutting guides and medical devices to scaffolds. The process of printing in 3 dimensions of cells, extracellular matrix (ECM) and biomaterials (bioinks, powders, etc.) to generate in vitro and/or in vivo tissue analogue structures has been termed bioprinting. To further advance in additive biomanufacturing, there are many aspects that we can learn from the wider additive manufacturing (AM) industry, which have progressed tremendously since its introduction into the manufacturing sector. First, this review gives an overview of additive manufacturing and both industry and academia efforts in addressing specific challenges in the AM technologies to drive toward AM-enabled industrial revolution. After which, considerations of poly(lactides) as a biomaterial in additive biomanufacturing are discussed. Challenges in wider additive biomanufacturing field are discussed in terms of (a) biomaterials; (b) computer-aided design, engineering and manufacturing; (c) AM and additive biomanufacturing printers hardware; and (d) system integration. Finally, the outlook for additive biomanufacturing was discussed. Copyright © 2016 Elsevier B.V. All rights reserved.

40 CFR 82.18 - Availability of production in addition to baseline production allowances for class II controlled...

Code of Federal Regulations, 2014 CFR

2014-07-01

... permitted under the Montreal Protocol or to receive from the person for the current control period some... production quantities: (A) The maximum production that the nation is allowed under the Protocol minus the...

Impact of trace element addition on biogas production from food industrial waste--linking process to microbial communities.

PubMed

Feng, Xin Mei; Karlsson, Anna; Svensson, Bo H; Bertilsson, Stefan

2010-10-01

Laboratory-scale reactors treating food industry waste were used to investigate the effects of additions of cobalt (Co), nickel/molybdenum/boron (Ni/Mo/B) and selenium/tungsten (Se/W) on the biogas process and the associated microbial community. The highest methane production (predicted value: 860 mL g(-1) VS) was linked to high Se/W concentrations in combination with a low level of Co. A combination of quantitative real-time PCR of 16S rRNA genes, terminal restriction fragment length polymorphism (T-RFLP) and clone library sequencing was used for the community analysis. The T-RFLP data show a higher diversity for bacteria than for archaea in all the treatments. The most abundant bacterial population (31-55% of the total T-RFLP fragments' intensity) was most closely related to Actinomyces europaeus (94% homology). Two dominant archaeal populations shared 98-99% sequence homology with Methanosarcina siciliae and Methanoculleus bourgensis, respectively. Only limited influence of the trace metal additions was found on the bacterial community composition, with two bacterial populations responding to the addition of a combination of Ni/Mo/B, while the dominant archaeal populations were influenced by the addition of Ni/Mo/B and/or Se/W. The maintenance of methanogenic activity was largely independent of archaeal community composition, suggesting a high degree of functional redundancy in the methanogens of the biogas reactors. © 2010 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.

Impact of Obesity on Work Productivity in Different US Occupations: Analysis of the National Health and Wellness Survey 2014 to 2015.

PubMed

Kudel, Ian; Huang, Joanna C; Ganguly, Rahul

2018-01-01

The aim of this study was to quantify the relationship between workers' body mass index and work productivity within various occupations. Data from two administrations (2014 and 2015) of the United States (US) National Health and Wellness Survey, an Internet-based survey administered to an adult sample of the US population, were used for this study (n = 59,772). Occupation was based on the US Department of Labor's 2010 Standardized Occupation Codes. Outcomes included work productivity impairment and indirect costs of missed work time. Obesity had the greatest impact on work productivity in Construction, followed by Arts and Hospitality occupations. Outcomes varied across occupations; multivariable analyses found significant differences in work productivity impairment and indirect costs between normal weight and at least one obesity class. Obesity differentially impacted productivity and costs, depending upon occupation.

Impact of green tea extract addition on oxidative changes in the lipid fraction of pastry products.

PubMed

Żbikowska, Anna; Kowalska, Małgorzata; Rutkowska, Jarosława; Kozłowska, Mariola; Onacik-Gür, Sylwia

2017-01-01

Alongside flour, fat is the key ingredient of sponge cakes, including those with long shelf lives. It is an unstable food component, whose quality and nutritional safety depend on the composition and pres- ence of oxidation products. Consumption of fat oxidation products adversely affects the human body and contributes to the incidence of a number of medical conditions. Qualitative changes in fats extracted from thermostat sponge cakes with and without antioxidant additions were determined in this study. In the study, two types of antioxidant were used: natural - green tea extract in three doses (0.02%; 0.2% and 1.0%) and synthetic BHA (0.02%) and 100%, solid bakery shortening. Sponge-cakes were thermostatted at temperatures 63°C after twenty-eight days. In this study, the quality of the lipid fraction was analyzed. The amount of primary (PV) and secondary (AnV) oxidation products was determined, and   a Rancimat test was performed. Adding antioxidants to fats varied in the degree to which oxidation processes of lipids fractions were inhibited. The peroxide value after twenty-eight days of thermostatting ranged from 3.57 meq O/kg (BHA) and 11.14 O meq/kg (extract content - 1%) to 62.85 meq O/kg (control sample). In turn, the value of AnV after the storage period ranged from 4.84 (BHA) and 6.71 (extract content - 1%) to 16.83 (control sample). The best protective effects in the process of oxidation was achieved by BHA. The longest in- duction time and the lowest peroxide value and anisidine value were obtained for this antioxidant. It was achieved after twenty-eight days of fat thermostatting. Nonetheless, the results demonstrated it is possible to use the commercially available green tea extract to slow the adverse process of fat oxidation in sponge cake products.

Quantification of Methane Leaks from Abandoned Oil and Gas Wells in California

NASA Astrophysics Data System (ADS)

Lebel, E.; Kang, M.; Lu, H.; Jackson, R. B.

2016-12-01

Abandoned oil and gas wells can provide a pathway for subterranean methane and other gases to be emitted to the atmosphere. However, abandoned wells are unaccounted for in greenhouse gas emissions inventories. While relatively little is known about abandoned wells, previous studies have shown that emissions from abandoned wells contribute approximately 4-7% of anthropogenic methane emissions in Pennsylvania (Kang et al. 2014) and <1% of regional methane emissions in oil and gas producing regions of Colorado, Utah, Ohio, and Wyoming (Townsend-Small et al. 2015). Another study (Boothroyd et al. 2016) has shown that 30% of abandoned wells in the UK have a positive surface methane flux. California has a long history of oil and gas production, beginning from the 1860s, and currently ranks third in oil production by state. As a result, there are more than 100,000 wells across the state. Our study uses static flux chambers to measure individual abandoned wells in California to estimate state-wide methane emissions from these wells. In addition to measuring methane concentrations, we measure ethane, propane, isobutane, n-butane, and 13-CH4 to understand whether this methane has a biogenic or thermogenic source. We hope that our research will determine whether or not abandoned oil and gas wells are a significant source of anthropogenic methane emissions in California. Our results along with measurements in other parts of the United States can be used to scale up methane emission estimates to the national level, accounting for the millions of abandoned wells in the country.

Elaboration And Characterization Of Foam Glass Based On Cullet With Addition Of Soluble Silicates

NASA Astrophysics Data System (ADS)

Ayadi, A.; Stiti, N.; Benhaoua, F.; Boumchedda, K.; Lerari, Y.

2011-01-01

The politics of the energy saving and of the acoustic comfort buildings is at the heart of the research of new compounds permitting to improve the materials performance actually commercialised. With this aim in view, we'll purpose to elaborate a porous material (foam glass) with addition of soluble silicates (up to 40%) of which the principal material is the waste glass in order to recycle it and improving the present laws about the waste products in closed circuit: (Finished products ← waste products← finished products). The investigations have shown that grinding waste glass to particle size less than 0.1 mm and adding 1% of Ca CO3 content provide production of material with the following properties: particle density 0,5 g/cm3, strength 17,50 MPa and water adsorption 95%, the temperature for foaming ranges were determined at 850° C. The microstructures are homogenous, with pore sizes up to 2 mm. The addition of soluble silicates (up to 40%) has resulted in the foam glass of very high porosity. The foam glass is counted among the new glass products meeting certain requirements sought comfort in the building industry in particular (thermal and acoustic insulation). The product obtained present of excellent properties thermal (λ = 0,031 W/m° C) and acoustic (R = 15 dB).

Utilization of Electric Arc Furnace Dust as raw material for the production of ceramic and concrete building products.

PubMed

Sikalidis, Constantine; Mitrakas, Manassis

2006-01-01

The up to 20 wt% addition of the Electric Arc Furnace Dust (EAFD) hazardous waste on the properties of extruded clay-based ceramic building products fired at various temperatures (850 to 1050 degrees C), as well as of dolomite-concrete products was investigated. Chemical, mineralogical and particle size distribution analyses were performed in order to characterize the used EAFD. The results showed that the ceramic specimens prepared had water absorption, firing shrinkage, apparent density, mechanical strength, colour and leaching behaviour within accepted limits. Addition of 7.5 to 15 wt% EAFD presented improved properties, while 20 wt% seems to be the upper limit. Dolomite-concrete specimens were prepared by vibration and press-forming of mixtures containing cement, sand, dolomite, EAFD and water. Modulus of rupture values were significantly increased by the addition of EAFD. The leaching tests showed stabilization of all toxic metals within the sintered ceramic structure, while the leaching behaviour of lead in dolomite-concrete products needs further detailed study.

Antibiotics: natural products essential to human health.

PubMed

Demain, Arnold L

2009-11-01

For more than 50 years, natural products have served us well in combating infectious bacteria and fungi. Microbial and plant secondary metabolites helped to double our life span during the 20th century, reduced pain and suffering, and revolutionized medicine. Most antibiotics are either (i) natural products of microorganisms, (ii) semi-synthetically produced from natural products, or (iii) chemically synthesized based on the structure of the natural products. Production of antibiotics began with penicillin in the late 1940s and proceeded with great success until the 1970-1980s when it became harder and harder to discover new and useful products. Furthermore, resistance development in pathogens became a major problem, which is still with us today. In addition, new pathogens are continually emerging and there are still bacteria that are not eliminated by any antibiotic, e.g., Pseudomonas aeruginosa. In addition to these problems, many of the major pharmaceutical companies have abandoned the antibiotic field, leaving much of the discovery efforts to small companies, new companies, and the biotechnology industries. Despite these problems, development of new antibiotics has continued, albeit at a much lower pace than in the last century. We have seen the (i) appearance of newly discovered antibiotics (e.g., candins), (ii) development of old but unutilized antibiotics (e.g., daptomycin), (iii) production of new semi-synthetic versions of old antibiotics (e.g., glycylcyclines, streptogrammins), as well as the (iv) very useful application of old but underutilized antibiotics (e.g., teicoplanin).

Enhanced sugar production from pretreated barley straw by additive xylanase and surfactants in enzymatic hydrolysis for acetone-butanol-ethanol fermentation.

PubMed

Yang, Ming; Zhang, Junhua; Kuittinen, Suvi; Vepsäläinen, Jouko; Soininen, Pasi; Keinänen, Markku; Pappinen, Ari

2015-01-01

This study aims to improve enzymatic sugar production from dilute sulfuric acid-pretreated barley straw for acetone-butanol-ethanol (ABE) fermentation. The effects of additive xylanase and surfactants (polyethylene glycol [PEG] and Tween) in an enzymatic reaction system on straw hydrolysis yields were investigated. By combined application of 2g/100g dry-matter (DM) xylanase and PEG 4000, the glucose yield was increased from 53.2% to 86.9% and the xylose yield was increased from 36.2% to 70.2%, which were considerably higher than results obtained with xylanase or surfactant alone. The ABE fermentation of enzymatic hydrolysate produced 10.8 g/L ABE, in which 7.9 g/L was butanol. The enhanced sugar production increased the ABE yield from 93.8 to 135.0 g/kg pretreated straw. The combined application of xylanase and surfactants has a large potential to improve sugar production from barley straw pretreated with a mild acid and that the hydrolysate showed good fermentability in ABE production. Copyright © 2015 Elsevier Ltd. All rights reserved.

Effect of iron and magnesium addition for ethanol production from the conversion of palm oil mill effluent by anaerobic processes

NASA Astrophysics Data System (ADS)

Handajani, M.; Gumilar, A.; Syafila, M.

2018-01-01

Nowadays, crisis of the energy is the main problem in the world. Currently, most the energy resource derived from the fossil material that cannot be refurbished. Ethanol is an alternative fuel that content as a fossil fuels. Wastewater with the high concentration of the organic can be used for the ethanol production to replace foodstuff as a raw material. In this study, palm oil mill effluent (POME) with the concentration of COD is 24,500 mg/L has been used as a substrate. The purpose of this study was to determine the effect of the metal addition in the substrate metabolic pathways. Circulating batch reactor (CBR) is used with the flushing N2 1L/min for 24 hours and continued operates for 72 hours by internal biogas. The additional variation concentration of Fe(II) ion are 0.5; 1.0 and 2.5 mg/L, and Mg(II) are 0.5 and 1.5 mg/L were added by combination. The results showed that the combination of Fe (II) 2.5 mg/L and Mg(II) 1.5 mg/L produced the highest ethanol concentration is 715.8 mg/L and degree of acidification (DA) 0.284-0.357. Another combination of Fe(II) and Mg(II) provide results for the ethanol production 463.7-689.7 mg/L with the rate of ethanol production is 1.09-26.5 mg/L/hour.

Additively Manufactured, Net Shape Powder Metallurgy Cans for Valves Used in Energy Production

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peter, William H.; Gandy, David; Lannom, Robert

This CRADA NFE-14-05241 was conducted as a Technical Collaboration project within the Oak Ridge National Laboratory (ORNL) Manufacturing Demonstration Facility (MDF) sponsored by the US Department of Energy Advanced Manufacturing Office (CPS Agreement Number 24761). Opportunities for MDF technical collaborations are listed in the announcement “Manufacturing Demonstration Facility Technology Collaborations for US Manufacturers in Advanced Manufacturing and Materials Technologies” posted at http://web.ornl.gov/sci/manufacturing/docs/FBO-ORNL-MDF-2013-2.pdf. The goal of technical collaborations is to engage industry partners to participate in short-term, collaborative projects within the Manufacturing Demonstration Facility (MDF) to assess applicability and of new energy efficient manufacturing technologies. Research sponsored by the U.S. Departmentmore » of Energy, Office of Energy Efficiency and Renewable Energy, Advanced Manufacturing Office, under contract DE-AC05-00OR22725 with UT-Battelle, LLC.ORNL would like to acknowledge the leadership of EPRI in pulling together the extensive team and managing the execution of the project. In addition, ORNL would like to acknowledge the other contributions of the team members associated with this project. Quintus provided time, access, expertise, and labor of their hydro forming capabilities to evaluate both conventional and additively manufactured tools through this process. Crane ChemPharma Energy provided guidance and information on valve geometries. Carpenter Powder Products was involved with the team providing information on powder processing as it pertains to the canning and hot isostatic pressing of powder. on providing powder and knowledge as it pertains to powder supply for hot isostatic pressing; they also provided powder for the test trials by the industrial team. Bodycote provided guidance on hot isostatic pressing and can requirements. They were also responsible for the hot isostatic pressing of the test

Evaluating the Relationship Between Seismicity and Subsurface Well Activity in Utah

NASA Astrophysics Data System (ADS)

Lajoie, L. J.; Bennett, S. E. K.

2014-12-01

Understanding the relationship between seismicity and subsurface well activity is crucial to evaluating the seismic hazard of transient, non-tectonic seismicity. Several studies have demonstrated correlations between increased frequency of earthquake occurrence and the injection/production of fluids (e.g. oil, water) in nearby subsurface wells in intracontinental settings (e.g. Arkansas, Colorado, Ohio, Oklahoma, Texas). Here, we evaluate all earthquake magnitudes for the past 20-30 years across the diverse seismotectonic settings of Utah. We explore earthquakes within 5 km and subsequent to completion dates of oil and gas wells. We compare seismicity rates prior to well establishment with rates after well establishment in an attempt to discriminate between natural and anthropogenic earthquakes in areas of naturally high background seismicity. In a few central Utah locations, we find that the frequency of shallow (0-10 km) earthquakes increased subsequent to completion of gas wells within 5 km, and at depths broadly similar to bottom hole depths. However, these regions typically correspond to mining regions of the Wasatch Plateau, complicating our ability to distinguish between earthquakes related to either well activity or mining. We calculate earthquake density and well density and compare their ratio (earthquakes per area/wells per area) with several published metrics of seismotectonic setting. Areas with a higher earthquake-well ratio are located in relatively high strain regions (determined from GPS) associated with the Intermountain Seismic Belt, but cannot be attributed to any specific Quaternary-active fault. Additionally, higher ratio areas do not appear to coincide with anomalously high heat flow values, where rocks are typically thermally weakened. Incorporation of timing and volume data for well injection/production would allow for more robust temporal statistical analysis and hazard analysis.

Warming and Nitrogen Addition Alter Photosynthetic Pigments, Sugars and Nutrients in a Temperate Meadow Ecosystem.

PubMed

Zhang, Tao; Yang, Shaobo; Guo, Rui; Guo, Jixun

2016-01-01

Global warming and nitrogen (N) deposition have an important influence on terrestrial ecosystems; however, the influence of warming and N deposition on plant photosynthetic products and nutrient cycling in plants is not well understood. We examined the effects of 3 years of warming and N addition on the plant photosynthetic products, foliar chemistry and stoichiometric ratios of two dominant species, i.e., Leymus chinensis and Phragmites communis, in a temperate meadow in northeastern China. Warming significantly increased the chlorophyll content and soluble sugars in L. chinensis but had no impact on the carotenoid and fructose contents. N addition caused a significant increase in the carotenoid and fructose contents. Warming and N addition had little impact on the photosynthetic products of P. communis. Warming caused significant decreases in the N and phosphorus (P) concentrations and significantly increased the carbon (C):P and N:P ratios of L. chinensis, but not the C concentration or the C:N ratio. N addition significantly increased the N concentration, C:P and N:P ratios, but significantly reduced the C:N ratio of L. chinensis. Warming significantly increased P. communis C and P concentrations, and the C:N and C:P ratios, whereas N addition increased the C, N and P concentrations but had no impact on the stoichiometric variables. This study suggests that both warming and N addition have direct impacts on plant photosynthates and elemental stoichiometry, which may play a vital role in plant-mediated biogeochemical cycling in temperate meadow ecosystems.

Warming and Nitrogen Addition Alter Photosynthetic Pigments, Sugars and Nutrients in a Temperate Meadow Ecosystem

PubMed Central

Zhang, Tao; Yang, Shaobo; Guo, Rui; Guo, Jixun

2016-01-01

Global warming and nitrogen (N) deposition have an important influence on terrestrial ecosystems; however, the influence of warming and N deposition on plant photosynthetic products and nutrient cycling in plants is not well understood. We examined the effects of 3 years of warming and N addition on the plant photosynthetic products, foliar chemistry and stoichiometric ratios of two dominant species, i.e., Leymus chinensis and Phragmites communis, in a temperate meadow in northeastern China. Warming significantly increased the chlorophyll content and soluble sugars in L. chinensis but had no impact on the carotenoid and fructose contents. N addition caused a significant increase in the carotenoid and fructose contents. Warming and N addition had little impact on the photosynthetic products of P. communis. Warming caused significant decreases in the N and phosphorus (P) concentrations and significantly increased the carbon (C):P and N:P ratios of L. chinensis, but not the C concentration or the C:N ratio. N addition significantly increased the N concentration, C:P and N:P ratios, but significantly reduced the C:N ratio of L. chinensis. Warming significantly increased P. communis C and P concentrations, and the C:N and C:P ratios, whereas N addition increased the C, N and P concentrations but had no impact on the stoichiometric variables. This study suggests that both warming and N addition have direct impacts on plant photosynthates and elemental stoichiometry, which may play a vital role in plant-mediated biogeochemical cycling in temperate meadow ecosystems. PMID:27171176

Changes in the process performance, sludge production and microbial activity in an activated sludge reactor with addition of a metabolic uncoupler under different operating conditions.

PubMed

Ferrer-Polonio, E; Fernández-Navarro, J; Alonso-Molina, J L; Amorós-Muñoz, I; Bes-Piá, A; Mendoza-Roca, J A

2017-12-01

Sludge production in wastewater treatment plants is nowadays a big concern due to the high produced amounts and their characteristics. Consequently, the study of techniques that reduce the sludge generation in wastewater treatment plants is becoming of great importance. In this work, four laboratory sequencing batch reactors (SBRs), which treated municipal wastewater, were operated to study the effect of adding the metabolic uncoupler 3,3',4',5-tetrachlorosalicylanilide (TCS) on the sludge reduction, the SBRs performance and the microbial hydrolytic enzymatic activities (MHEA). In addition, different operating conditions of the SBRs were tested to study the effect of the TCS on the process: two dissolved oxygen (DO) concentrations (2 and 9 mg L -1 ) and two F/M ratio (0.18 and 0.35 g COD·g MLVSS -1 ·d -1 ). The sludge production decreased under high DO concentrations. At the same time, the DNA and EPS production increased in the four SBRs. After these stress conditions, the performance of the reactors were recovered when DO was around 2 mg L -1 . From that moment on, results showed that TCS addition implied a reduction of the adenosine triphosphate (ATP) production, which implied a decrease in the sludge production. In spite of this reduction, the SBRs performances did not decay due to the increase in the global MHEA. Additionally, the sludge reduction was enhanced by the increase of the F/M ratio, achieving 28% and 60% of reduction for the low and the high F/M ratio, respectively. Copyright © 2017 Elsevier Ltd. All rights reserved.

Work, Health, And Worker Well-Being: Roles And Opportunities For Employers.

PubMed

McLellan, Robert K

2017-02-01

Work holds the promise of supporting and promoting health. It also carries the risk of injury, illness, and death. In addition to harms posed by traditional occupational health hazards, such as physically dangerous workplaces, work contributes to health problems with multifactorial origins such as unhealthy lifestyles, psychological distress, and chronic disease. Not only does work affect health, but the obverse is true: Unhealthy workers are more frequently disabled, absent, and less productive, and they use more health care resources, compared to their healthy colleagues. The costs of poor workforce health are collectively borne by workers, employers, and society. For business as well as altruistic reasons, employers may strive to cost-effectively achieve the safest, healthiest, and most productive workforce possible. Narrowly focused health goals are giving way to a broader concept of employee well-being. This article explores the relationship between health and work, outlines opportunities for employers to make this relationship health promoting, and identifies areas needing further exploration. Project HOPE—The People-to-People Health Foundation, Inc.

Surface modification of biomaterials and biomedical devices using additive manufacturing.

PubMed

Bose, Susmita; Robertson, Samuel Ford; Bandyopadhyay, Amit

2018-01-15

The demand for synthetic biomaterials in medical devices, pharmaceutical products and, tissue replacement applications are growing steadily due to aging population worldwide. The use for patient matched devices is also increasing due to availability and integration of new technologies. Applications of additive manufacturing (AM) or 3D printing (3DP) in biomaterials have also increased significantly over the past decade towards traditional as well as innovative next generation Class I, II and III devices. In this review, we have focused our attention towards the use of AM in surface modified biomaterials to enhance their in vitro and in vivo performances. Specifically, we have discussed the use of AM to deliberately modify the surfaces of different classes of biomaterials with spatial specificity in a single manufacturing process as well as commented on the future outlook towards surface modification using AM. It is widely understood that the success of implanted medical devices depends largely on favorable material-tissue interactions. Additive manufacturing has gained traction as a viable and unique approach to engineered biomaterials, for both bulk and surface properties that improve implant outcomes. This review explores how additive manufacturing techniques have been and can be used to augment the surfaces of biomedical devices for direct clinical applications. Copyright © 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

Fabricating Superior NiAl Bronze Components through Wire Arc Additive Manufacturing.

PubMed

Ding, Donghong; Pan, Zengxi; van Duin, Stephen; Li, Huijun; Shen, Chen

2016-08-03

Cast nickel aluminum bronze (NAB) alloy is widely used for large engineering components in marine applications due to its excellent mechanical properties and corrosion resistance. Casting porosity, as well as coarse microstructure, however, are accompanied by a decrease in mechanical properties of cast NAB components. Although heat treatment, friction stir processing, and fusion welding were implemented to eliminate porosity, improve mechanical properties, and refine the microstructure of as-cast metal, their applications are limited to either surface modification or component repair. Instead of traditional casting techniques, this study focuses on developing NAB components using recently expanded wire arc additive manufacturing (WAAM). Consumable welding wire is melted and deposited layer-by-layer on substrates producing near-net shaped NAB components. Additively-manufactured NAB components without post-processing are fully dense, and exhibit fine microstructure, as well as comparable mechanical properties, to as-cast NAB alloy. The effects of heat input from the welding process and post-weld-heat-treatment (PWHT) are shown to give uniform NAB alloys with superior mechanical properties revealing potential marine applications of the WAAM technique in NAB production.

Fabricating Superior NiAl Bronze Components through Wire Arc Additive Manufacturing

PubMed Central

Ding, Donghong; Pan, Zengxi; van Duin, Stephen; Li, Huijun; Shen, Chen

2016-01-01

Cast nickel aluminum bronze (NAB) alloy is widely used for large engineering components in marine applications due to its excellent mechanical properties and corrosion resistance. Casting porosity, as well as coarse microstructure, however, are accompanied by a decrease in mechanical properties of cast NAB components. Although heat treatment, friction stir processing, and fusion welding were implemented to eliminate porosity, improve mechanical properties, and refine the microstructure of as-cast metal, their applications are limited to either surface modification or component repair. Instead of traditional casting techniques, this study focuses on developing NAB components using recently expanded wire arc additive manufacturing (WAAM). Consumable welding wire is melted and deposited layer-by-layer on substrates producing near-net shaped NAB components. Additively-manufactured NAB components without post-processing are fully dense, and exhibit fine microstructure, as well as comparable mechanical properties, to as-cast NAB alloy. The effects of heat input from the welding process and post-weld-heat-treatment (PWHT) are shown to give uniform NAB alloys with superior mechanical properties revealing potential marine applications of the WAAM technique in NAB production. PMID:28773774

Analytical filtration model for nonlinear viscoplastic oil in the theory of oil production stimulation and heating of oil reservoir in a dual-well system

NASA Astrophysics Data System (ADS)

Ivanovich Astafev, Vladimir; Igorevich Gubanov, Sergey; Alexandrovna Olkhovskaya, Valeria; Mikhailovna Sylantyeva, Anastasia; Mikhailovich Zinovyev, Alexey

2018-02-01

Production of high-viscosity oil and design of field development systems for such oil is one of the most promising directions in the development of world oil industry. The ability of high-viscosity oil to show in filtration process properties typical for non-Newtonian systems is proven by experimental studies. Nonlinear relationship between the pressure gradient and the rate of oil flow is due to interaction of high-molecular substances, in particular, asphaltenes and tars that form a plastic structure in it. The authors of this article have used the analytical model of stationary influx of nonlinear viscoplastic oil to the well bottom in order to provide rationale for the intensifying impact on a reservoir. They also have analyzed the method of periodic heating of productive reservoir by means of dual-wells. The high-temperature source is placed at the bottom of the vertical well, very close to the reservoir; at the same time the side well, located outside the zone of expected rock damage, is used for production. Suggested method of systemic treatment of reservoirs with dual wells can be useful for small fields of high-viscosity oil. The effect is based on the opportunity to control the structural and mechanical properties of high-viscosity oil and to increase depletion of reserves.

Cincinnati Big Area Additive Manufacturing (BAAM)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duty, Chad E.; Love, Lonnie J.

Oak Ridge National Laboratory (ORNL) worked with Cincinnati Incorporated (CI) to demonstrate Big Area Additive Manufacturing which increases the speed of the additive manufacturing (AM) process by over 1000X, increases the size of parts by over 10X and shows a cost reduction of over 100X. ORNL worked with CI to transition the Big Area Additive Manufacturing (BAAM) technology from a proof-of-principle (TRL 2-3) demonstration to a prototype product stage (TRL 7-8).

Market surveillance on non-halal additives incorporated in surimi based products using polymerase chain reaction (PCR)-southern hybridization analysis

NASA Astrophysics Data System (ADS)

Aravindran, S.; Sahilah, A. M.; Aminah, A.

2014-09-01

Halal surveillance on halal ingredients incorporated in surimi based products were studied using polymerase chain reaction (PCR)-southern hybridization on chip analysis. The primers used in this technique were targeted on mitochondria DNA (mtDNA) of cytochrome b (cyt b) gene sequence which able to differentiate 7 type (beef, chicken, duck, goat, buffalo, lamb and pork) of species on a single chip. 17 (n = 17*3) different brands of surimi-based product were purchased randomly from Selangor local market in January 2013. Of 17 brands, 3 (n = 3*3) brands were positive for chicken DNA, 1 (n = 1*3) brand was positive for goat DNA, and the remainder 13 brands (n = 13*3) have no DNA species detected. The sensitivity of PCR-southern hybridization primers to detect each meat species was 0.1 ng. In the present study, it is evidence that PCR-Southern Hybridization analysis offered a reliable result due to its highly specific and sensitive properties in detecting non-halal additive such as plasma protein incorporation in surimi-based product.

Additive-manufactured sandwich lattice structures: A numerical and experimental investigation

NASA Astrophysics Data System (ADS)

Fergani, Omar; Tronvoll, Sigmund; Brøtan, Vegard; Welo, Torgeir; Sørby, Knut

2017-10-01

The utilization of additive-manufactured lattice structures in engineered products is becoming more and more common as the competitiveness of AM as a production technology has increased during the past several years. Lattice structures may enable important weight reductions as well as open opportunities to build products with customized functional properties, thanks to the flexibility of AM for producing complex geometrical configurations. One of the most critical aspects related to taking AM into new application areas—such as safety critical products—is currently the limited understanding of the mechanical behavior of sandwich-based lattice structure mechanical under static and dynamic loading. In this study, we evaluate manufacturability of lattice structures and the impact of AM processing parameters on the structural behavior of this type of sandwich structures. For this purpose, we conducted static compression testing for a variety of geometry and manufacturing parameters. Further, the study discusses a numerical model capable of predicting the behavior of different lattice structure. A reasonably good correlation between the experimental and numerical results was observed.

7 CFR 51.489 - Well netted.

Code of Federal Regulations, 2010 CFR

2010-01-01

... FRESH FRUITS, VEGETABLES AND OTHER PRODUCTS 1,2 (INSPECTION, CERTIFICATION, AND STANDARDS) United States... characteristic of the variety the cantaloup is well covered with fully developed, well raised netting, some...

Gas production from a cold, stratigraphically-bounded gas hydrate deposit at the Mount Elbert Gas Hydrate Stratigraphic Test Well, Alaska North Slope: Implications of uncertainties

USGS Publications Warehouse

Moridis, G.J.; Silpngarmlert, S.; Reagan, M.T.; Collett, T.; Zhang, K.

2011-01-01

As part of an effort to identify suitable targets for a planned long-term field test, we investigate by means of numerical simulation the gas production potential from unit D, a stratigraphically bounded (Class 3) permafrost-associated hydrate occurrence penetrated in the BPXA-DOE-USGS Mount Elbert Gas Hydrate Stratigraphic Test Well on North Slope, Alaska. This shallow, low-pressure deposit has high porosities (?? = 0.4), high intrinsic permeabilities (k = 10-12 m2) and high hydrate saturations (SH = 0.65). It has a low temperature (T = 2.3-2.6 ??C) because of its proximity to the overlying permafrost. The simulation results indicate that vertical wells operating at a constant bottomhole pressure would produce at very low rates for a very long period. Horizontal wells increase gas production by almost two orders of magnitude, but production remains low. Sensitivity analysis indicates that the initial deposit temperature is by the far the most important factor determining production performance (and the most effective criterion for target selection) because it controls the sensible heat available to fuel dissociation. Thus, a 1 ??C increase in temperature is sufficient to increase the production rate by a factor of almost 8. Production also increases with a decreasing hydrate saturation (because of a larger effective permeability for a given k), and is favored (to a lesser extent) by anisotropy. ?? 2010.